NASA Astrophysics Data System (ADS)
Armstrong, Julian J.; Leigh, Matthew S.; Walton, Ian D.; Zvyagin, Andrei V.; Alexandrov, Sergey A.; Schwer, Stefan; Sampson, David D.; Hillman, David R.; Eastwood, Peter R.
2003-07-01
We describe a long-range optical coherence tomography system for size and shape measurement of large hollow organs in the human body. The system employs a frequency-domain optical delay line of a configuration that enables the combination of high-speed operation with long scan range. We compare the achievable maximum delay of several delay line configurations, and identify the configurations with the greatest delay range. We demonstrate the use of one such long-range delay line in a catheter-based optical coherence tomography system and present profiles of the human upper airway and esophagus in vivo with a radial scan range of 26 millimeters. Such quantitative upper airway profiling should prove valuable in investigating the pathophysiology of airway collapse during sleep (obstructive sleep apnea).
Kitahara, Hideaki; Tani, Masahiko; Hangyo, Masanori
2009-07-01
We developed a high-repetition-rate optical delay line based on a micromirror array and galvanometer mirror for terahertz time-domain spectroscopy. The micromirror array is fabricated by using the x-ray lithographic technology. The measurement of terahertz time-domain waveforms with the new optical delay line is demonstrated successfully up to 25 Hz.
Loaded delay lines for future RF pulse compression systems
DOE Office of Scientific and Technical Information (OSTI.GOV)
Jones, R.M.; Wilson, P.B.; Kroll, N.M.
1995-05-01
The peak power delivered by the klystrons in the NLCRA (Next Linear Collider Test Accelerator) now under construction at SLAC is enhanced by a factor of four in a SLED-II type of R.F. pulse compression system (pulse width compression ratio of six). To achieve the desired output pulse duration of 250 ns, a delay line constructed from a 36 m length of circular waveguide is used. Future colliders, however, will require even higher peak power and larger compression factors, which favors a more efficient binary pulse compression approach. Binary pulse compression, however, requires a line whose delay time is approximatelymore » proportional to the compression factor. To reduce the length of these lines to manageable proportions, periodically loaded delay lines are being analyzed using a generalized scattering matrix approach. One issue under study is the possibility of propagating two TE{sub o} modes, one with a high group velocity and one with a group velocity of the order 0.05c, for use in a single-line binary pulse compression system. Particular attention is paid to time domain pulse degradation and to Ohmic losses.« less
Microwave fiber optics delay line
NASA Astrophysics Data System (ADS)
Slayman, C.; Yen, H. W.
1980-01-01
A microwave delay line is one of the devices used in EW systems for preserving the frequency and phase contents of RF signals. For such applications, delay lines are required to have large dynamic range, wide bandwidth, low insertion loss, and a linear response. The basic components of a fiber-optics delay line are: an optical source, a wideband optical modulator, a spool of single-mode fiber with appropriate length to provide a given microwave signal delay, and a high-speed photodetector with an RF amplifier. This contract program is to study the feasibility of such a fiber-optic delay line in the frequency range of 4.0 to 6.5 GHz. The modulation scheme studied is the direct modulation of injection lasers. The most important issue identified is the frequency response of the injection laser and the photodetector.
Design of hybrid optical delay line for automotive radar test system
NASA Astrophysics Data System (ADS)
Son, Byung-Hee; Kim, Kwang-Jin; Li, Ye; Park, Chang-In; Choi, Young-Wan
2015-03-01
In this paper, hybrid optical delay line (HODL) which is demanded on automotive radar test system (RTS) is proposed and demonstrated. HODL is composed with coaxial cable in short delay time (< 32 nsec) and optical fiber in long delay time (>= 32 nsec) which are considering the volume, loss and frequency characteristics. Also, the optical transceiver that has the bandwidth of 1 GHz is designed for frequency modulated continuous wave (FMCW). Experimental results show that the S21 is +/- 0.5 dB in the optical transceiver and +/- 1.7 dB in the whole system at 3.7 GHz ~ 4.7 GHz. The resolution of delay time is 1 ns and the delay flatness is +/- 0.23 ns.
Phase-locked-loop-based delay-line-free picosecond electro-optic sampling system
NASA Astrophysics Data System (ADS)
Lin, Gong-Ru; Chang, Yung-Cheng
2003-04-01
A delay-line-free, high-speed electro-optic sampling (EOS) system is proposed by employing a delay-time-controlled ultrafast laser diode as the optical probe. Versatile optoelectronic delay-time controllers (ODTCs) based on modified voltage-controlled phase-locked-loop phase-shifting technologies are designed for the laser. The integration of the ODTC circuit and the pulsed laser diode has replaced the traditional optomechanical delay-line module used in the conventional EOS system. This design essentially prevents sampling distortion from misalignment of the probe beam, and overcomes the difficulty in sampling free-running high-speed transients. The maximum tuning range, error, scanning speed, tuning responsivity, and resolution of the ODTC are 3.9π (700°), <5% deviation, 25-2405 ns/s, 0.557 ps/mV, and ˜1 ps, respectively. Free-running wave forms from the analog, digital, and pulsed microwave signals are sampled and compared with those measured by the commercial apparatus.
NASA Astrophysics Data System (ADS)
Harrington, M.; Kujawski, J. T.; Adrian, M. L.; Weatherwax, A. T.
2013-12-01
Electrons are, by definition, a fundamental, chemical and electromagnetic constituent of any plasma. This is especially true within the partially ionized plasmas of Earth's ionosphere where electrons are a critical component of a vast array of plasma processes. Siena College is working on a novel method of processing information from electron spectrometer anodes using delay line techniques and inexpensive COTS electronics to track the movement of high-energy particles. Electron spectrometers use a variety of techniques to determine where an amplified electron cloud falls onto a collecting surface. One traditional method divides the collecting surface into sectors and uses a single detector for each sector. However, as the angular and spatial resolution increases, so does the number of detectors, increasing power consumption, cost, size, and weight of the system. An alternative approach is to connect each sector with a delay line built within the PCB material which is shielded from cross talk by a flooded ground plane. Only one pair of detectors (e.g., one at each end of the chain) are needed with the delay line technique which is different from traditional delay line detectors which use either Application Specific Integrated Circuits (ASICs) or very fast clocks. In this paper, we report on the implementation and testing of a delay line detector using a low-cost Xilinx FPGA and a thirty-two sector delay system. This Delay Line Detector has potential satellite and rocket flight applications due to its low cost, small size and power efficiency
Constructing Hopf bifurcation lines for the stability of nonlinear systems with two time delays
NASA Astrophysics Data System (ADS)
Nguimdo, Romain Modeste
2018-03-01
Although the plethora real-life systems modeled by nonlinear systems with two independent time delays, the algebraic expressions for determining the stability of their fixed points remain the Achilles' heel. Typically, the approach for studying the stability of delay systems consists in finding the bifurcation lines separating the stable and unstable parameter regions. This work deals with the parametric construction of algebraic expressions and their use for the determination of the stability boundaries of fixed points in nonlinear systems with two independent time delays. In particular, we concentrate on the cases for which the stability of the fixed points can be ascertained from a characteristic equation corresponding to that of scalar two-delay differential equations, one-component dual-delay feedback, or nonscalar differential equations with two delays for which the characteristic equation for the stability analysis can be reduced to that of a scalar case. Then, we apply our obtained algebraic expressions to identify either the parameter regions of stable microwaves generated by dual-delay optoelectronic oscillators or the regions of amplitude death in identical coupled oscillators.
Prototype high speed optical delay line for stellar interferometry
NASA Astrophysics Data System (ADS)
Colavita, M. M.; Hines, B. E.; Shao, M.; Klose, G. J.; Gibson, B. V.
1991-12-01
The long baselines of the next-generation ground-based optical stellar interferometers require optical delay lines which can maintain nm-level path-length accuracy while moving at high speeds. NASA-JPL is currently designing delay lines to meet these requirements. The design is an enhanced version of the Mark III delay line, with the following key features: hardened, large diameter wheels, rather than recirculating ball bearings, to reduce mechanical noise; a friction-drive cart which bears the cable-dragging forces, and drives the optics cart through a force connection only; a balanced PZT assembly to enable high-bandwidth path-length control; and a precision aligned flexural suspension for the optics assembly to minimize bearing noise feedthrough. The delay line is fully programmable in position and velocity, and the system is controlled with four cascaded software feedback loops. Preliminary performance is a jitter in any 5 ms window of less than 10 nm rms for delay rates of up to 28 mm/s; total jitter is less than 10 nm rms for delay rates up to 20 mm/s.
Centering a DDR Strobe in the Middle of a Data Packet
NASA Technical Reports Server (NTRS)
Johnson, Michael; Nelson, Dave; Seefeldt, James; Roper, Weston; Passow, Craig
2014-01-01
The Orion CEV Northstar ASIC (application- specific integrated circuit) project required a DDR (double data rate) memory bus driver/receiver (DDR PHY block) to interface with external DDR memory. The DDR interface (JESD79C) is based on a source synchronous strobe (DQS\\) that is sent along with each packet of data (DQ). New data is provided concurrently with each edge of strobe and is sent irregularly. In order to capture this data, the strobe needs to be delayed and used to latch the data into a register. A circuit solves the need for training a DDR PRY block by incorporating a PVT-compensated delay element in the strobe path. This circuit takes an external reference clock signal and uses the regular clock to calibrate a known delay through a data path. The compensated delay DQS signal is then used to capture the DQ data in a normal register. This register structure can be configured as a FIFO (first in first out), in order to transfer data from the DDR domain to the system clock domain. This design is different in that it does not rely upon the need for training the system response, nor does it use a PLL (phase locked loop) or a DLL (delay locked loop) to provide an offset of the strobe signal. The circuit is created using standard ASIC building blocks, plus the PVT (process, voltage, and temperature) compensated delay line. The design uses a globally available system clock as a reference, alleviating the need to operate synchronously with the remote memory. The reference clock conditions the PVT compensated delay line to provide a pre-determined amount of delay to any data signal that passes through this delay line. The delay line is programmed in degrees of offset, so that one could think of the clock period representing 360deg of delay. In an ideal environment, delaying the strobe 1/4 of a clock cycle (90deg) would place the strobe in the middle of the data packet. This delayed strobe can then be used to clock the data into a register, satisfying setup and hold requirements of the system.
Webcam autofocus mechanism used as a delay line for the characterization of femtosecond pulses.
Castro-Marín, Pablo; Kapellmann-Zafra, Gabriel; Garduño-Mejía, Jesús; Rosete-Aguilar, Martha; Román-Moreno, Carlos J
2015-08-01
In this work, we present an electromagnetic focusing mechanism (EFM), from a commercial webcam, implemented as a delay line of a femtosecond laser pulse characterization system. The characterization system consists on a second order autocorrelator based on a two-photon-absorption detection. The results presented here were performed for two different home-made femtosecond oscillators: Ti:sapph @ 820 nm and highly chirped pulses generated with an Erbium Doped Fiber @ 1550 nm. The EFM applied as a delay line represents an excellent alternative due its performance in terms of stability, resolution, and long scan range up to 3 ps. Due its low power consumption, the device can be connected through the Universal Serial Bus (USB) port. Details of components, schematics of electronic controls, and detection systems are presented.
Webcam autofocus mechanism used as a delay line for the characterization of femtosecond pulses
NASA Astrophysics Data System (ADS)
Castro-Marín, Pablo; Kapellmann-Zafra, Gabriel; Garduño-Mejía, Jesús; Rosete-Aguilar, Martha; Román-Moreno, Carlos J.
2015-08-01
In this work, we present an electromagnetic focusing mechanism (EFM), from a commercial webcam, implemented as a delay line of a femtosecond laser pulse characterization system. The characterization system consists on a second order autocorrelator based on a two-photon-absorption detection. The results presented here were performed for two different home-made femtosecond oscillators: Ti:sapph @ 820 nm and highly chirped pulses generated with an Erbium Doped Fiber @ 1550 nm. The EFM applied as a delay line represents an excellent alternative due its performance in terms of stability, resolution, and long scan range up to 3 ps. Due its low power consumption, the device can be connected through the Universal Serial Bus (USB) port. Details of components, schematics of electronic controls, and detection systems are presented.
Webcam autofocus mechanism used as a delay line for the characterization of femtosecond pulses
DOE Office of Scientific and Technical Information (OSTI.GOV)
Castro-Marín, Pablo; Kapellmann-Zafra, Gabriel; Garduño-Mejía, Jesús, E-mail: jesus.garduno@ccadet.unam.mx
2015-08-15
In this work, we present an electromagnetic focusing mechanism (EFM), from a commercial webcam, implemented as a delay line of a femtosecond laser pulse characterization system. The characterization system consists on a second order autocorrelator based on a two-photon-absorption detection. The results presented here were performed for two different home-made femtosecond oscillators: Ti:sapph @ 820 nm and highly chirped pulses generated with an Erbium Doped Fiber @ 1550 nm. The EFM applied as a delay line represents an excellent alternative due its performance in terms of stability, resolution, and long scan range up to 3 ps. Due its low powermore » consumption, the device can be connected through the Universal Serial Bus (USB) port. Details of components, schematics of electronic controls, and detection systems are presented.« less
Fiber-optic delay-line stabilization of heterodyne optical signal generator and method using same
NASA Technical Reports Server (NTRS)
Logan, Ronald T. (Inventor)
1997-01-01
The present invention is a laser heterodyne frequency generator system with a stabilizer for use in the microwave and millimeter-wave frequency ranges utilizing a photonic mixer as a photonic phase detector in a stable optical fiber delay-line. Phase and frequency fluctuations of the heterodyne laser signal generators are stabilized at microwave and millimeter wave frequencies by a delay line system operating as a frequency discriminator. The present invention is free from amplifier and mixer 1/.function. noise at microwave and millimeter-wave frequencies that typically limit phase noise performance in electronic cavity stabilized electronic oscillators. Thus, 1/.function. noise due to conventional mixers is eliminated and stable optical heterodyne generation of electrical signals is achieved.
An ultrasonic pseudorandom signal-correlation system
NASA Astrophysics Data System (ADS)
Elias, C. M.
1980-01-01
A working ultrasonic pseudorandom signal-correlation system is described which, unlike ultrasonic random signal-correlation systems, does not require an acoustic delay line. Elimination of the delay line allows faster data acquisition and better range resolution. The system uses two identical shift-register type generators to produce pseudonoise bursts which are subsequences of a 65 535-bit complementary m-sequence. One generator produces the transmitted bursts while the other generates identical reference bursts which start at a variable correlation delay time after the transmitted bursts. The reference bursts are cross-correlated with the received echoes to obtain the approximate impulse response of the transducer/specimen system under test. Range sidelobes are reduced by transmitting and correlating many bursts at a given correlation delay before incrementing the delay. Signal-to-sidelobe ratios of greater than 47 dB have been obtained using this method. Limitations of the system due to sampling constraints and the pseudonoise power spectrum are discussed, and the system design and implementation are outlined. Results of experimental characterization of the system show that the pseudorandom signal-correlation system has approximately the same range resolution as a conventional pulse-echo system but can yield a significant increase in signal-to-noise ratio (SNR).
Sensitivity of bandpass filters using recirculating delay-line structures
NASA Astrophysics Data System (ADS)
Heyde, Eric C.
1996-12-01
Recirculating delay lines have value notably as sensors and optical signal processors. Most useful applications depend on a high-finesse response from a network. A proof that, with given response parameters, more complex systems can produce behavior that is more stable to the effects of nonidealities than a single recirculating loop is presented.
Tang, Xiaoming; Qu, Hongchun; Wang, Ping; Zhao, Meng
2015-03-01
This paper investigates the off-line synthesis approach of model predictive control (MPC) for a class of networked control systems (NCSs) with network-induced delays. A new augmented model which can be readily applied to time-varying control law, is proposed to describe the NCS where bounded deterministic network-induced delays may occur in both sensor to controller (S-A) and controller to actuator (C-A) links. Based on this augmented model, a sufficient condition of the closed-loop stability is derived by applying the Lyapunov method. The off-line synthesis approach of model predictive control is addressed using the stability results of the system, which explicitly considers the satisfaction of input and state constraints. Numerical example is given to illustrate the effectiveness of the proposed method. Copyright © 2014 ISA. Published by Elsevier Ltd. All rights reserved.
Compact and low-cost THz QTDS system.
Probst, Thorsten; Rehn, Arno; Koch, Martin
2015-08-24
We present a terahertz quasi time domain spectroscopy (QTDS) system setup which is improved regarding cost and compactness. The diode laser is mounted directly onto the optical delay line, making the optical setup more compact. The system is operated using a Raspberry Pi and an additional sound card. This combination replaces the desktop/laptop computer, the lock-in-amplifier, the stage controller and the signal generator. We examined not only a commercially available stepper motor driven delay line, but also the repurposed internal mechanics from a DVD drive. We characterize the performance of the new system concept.
Roy, Manas K
2002-11-01
The technique of feed-forward amplitude control has been widely used in the linearization of power amplifiers for wireless communication systems. In this technique, an error signal due to third order intermodulation distortion (IMD) is extracted, amplified, and used to correct the delayed main line distorted signal. For example, a miniature prototype base station for the Global System for Mobile Communications/Code Division Multiple Access (GSM/CDMA) cellular system uses feed-forward amplifiers with bulky and expensive coaxial cables, about 20 feet in length, to provide about 25 ns of delay. This paper shows alternate space-saving approaches of achieving these delays using three different types of delay filters: electromagnetic interdigital/lumped (<2.5"), ceramic (<1.8"), and ladder-type surface acoustic wave (SAW) (0.15"). The delay lines introduce phase and amplitude imbalance and delay mismatch in the linearization loop due to fabrication tolerances. These adversely affect the IMD cancellation. Using an RF system simulation tool, this paper critically compares the IMD cancellation performance achieved using the three technologies. Simulation results show that the optimization of delay mismatch can achieve the desired cancellation more easily than other parameters. It is shown that, if the critical system parameter (phase deviation from linearity), is maintained at <2.5 degrees peak-to-peak over a 20 MHz bandwidth in the frequency range 855 MHz to 875 MHz, one can achieve 25 dB of IMD cancellation performance. This paper concludes with the suggestion of a set of realistic specifications for a miniature delay filter for the low power loop of the feed-forward amplifier.
NASA Astrophysics Data System (ADS)
Kim, Jisung; Kim, Saehan; Lee, Keekeun
2017-06-01
For the first time, a wireless and chipless neuron stimulator was developed by utilizing a surface acoustic wave (SAW) delay line, a diode-capacitor interface, a sharp metal tip, and antennas for the stimulation of neurons in the brain. The SAW delay line supersedes presently existing complex wireless transmission systems composed of a few thousands of transistors, enabling the fabrication of wireless and chipless transceiver systems. The diode-capacitor interface was used to convert AC signals to DC signals and induce stimulus pulses at a sharp metal probe. A 400 MHz RF energy was wirelessly radiated from antennas and then stimulation pulses were observed at a sharp gold probe. A ˜5 m reading distance was obtained using a 1 mW power from a network analyzer. The cycles of electromagnetic (EM) radiation from an antenna were controlled by shielding the antenna with an EM absorber. Stimulation pulses with different amplitudes and durations were successfully observed at the probe. The obtained pulses were ˜0.08 mV in amplitude and 3-10 Hz in frequency. Coupling-of-mode (COM) and SPICE modeling simulations were also used to determine the optimal structural parameters for SAW delay line and the values of passive elements. On the basis of the extracted parameters, the entire system was experimentally implemented and characterized.
NASA Technical Reports Server (NTRS)
Seefeldt, James (Inventor); Feng, Xiaoxin (Inventor); Roper, Weston (Inventor)
2013-01-01
A process, voltage, and temperature (PVT) compensation circuit and a method of continuously generating a delay measure are provided. The compensation circuit includes two delay lines, each delay line providing a delay output. The two delay lines may each include a number of delay elements, which in turn may include one or more current-starved inverters. The number of delay lines may differ between the two delay lines. The delay outputs are provided to a combining circuit that determines an offset pulse based on the two delay outputs and then averages the voltage of the offset pulse to determine a delay measure. The delay measure may be one or more currents or voltages indicating an amount of PVT compensation to apply to input or output signals of an application circuit, such as a memory-bus driver, dynamic random access memory (DRAM), a synchronous DRAM, a processor or other clocked circuit.
Acoustic Signal Processing in Photorefractive Optical Systems.
NASA Astrophysics Data System (ADS)
Zhou, Gan
This thesis discusses applications of the photorefractive effect in the context of acoustic signal processing. The devices and systems presented here illustrate the ideas and optical principles involved in holographic processing of acoustic information. The interest in optical processing stems from the similarities between holographic optical systems and contemporary models for massively parallel computation, in particular, neural networks. An initial step in acoustic processing is the transformation of acoustic signals into relevant optical forms. A fiber-optic transducer with photorefractive readout transforms acoustic signals into optical images corresponding to their short-time spectrum. The device analyzes complex sound signals and interfaces them with conventional optical correlators. The transducer consists of 130 multimode optical fibers sampling the spectral range of 100 Hz to 5 kHz logarithmically. A physical model of the human cochlea can help us understand some characteristics of human acoustic transduction and signal representation. We construct a life-sized cochlear model using elastic membranes coupled with two fluid-filled chambers, and use a photorefractive novelty filter to investigate its response. The detection sensitivity is determined to be 0.3 angstroms per root Hz at 2 kHz. Qualitative agreement is found between the model response and physiological data. Delay lines map time-domain signals into space -domain and permit holographic processing of temporal information. A parallel optical delay line using dynamic beam coupling in a rotating photorefractive crystal is presented. We experimentally demonstrate a 64 channel device with 0.5 seconds of time-delay and 167 Hz bandwidth. Acoustic signal recognition is described in a photorefractive system implementing the time-delay neural network model. The system consists of a photorefractive optical delay-line and a holographic correlator programmed in a LiNbO_3 crystal. We demonstrate the recognition of synthesized chirps as well as spoken words. A photorefractive ring resonator containing an optical delay line can learn temporal information through self-organization. We experimentally investigate a system that learns by itself and picks out the most-frequently -presented signals from the input. We also give results demonstrating the separation of two orthogonal temporal signals into two competing ring resonators.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Wang, Boyun; Wang, Tao, E-mail: wangtao@hust.edu.cn; Tang, Jian
2014-10-07
We theoretically propose a dynamic and ultrafast group delay tuning mechanism in two microcavities side-coupled to a waveguide system through external optical pump beams. The optical Kerr effect modulation method is applied to improve tuning rate with response time of subpicoseconds or even femtoseconds. The group delay of an all-optical analog to electromagnetically induced transparency effect can be controlled by tuning either the frequency of photonic crystal microcavities or the propagation phase of line waveguide. Group delay is controlled between 5.88 and 70.98 ps by dynamically tuning resonant frequencies of the microcavities. Alternatively, the group delay is controlled between 1.86more » and 12.08 ps by dynamically tuning the propagation phase of line waveguide. All observed schemes are analyzed rigorously through finite-difference time-domain simulations and coupled-mode formalism. Results show a new direction toward microstructure integration optical pulse trapping and all-optical dynamical storage of light devices in optical communication and quantum information processing.« less
A review on high-resolution CMOS delay lines: towards sub-picosecond jitter performance.
Abdulrazzaq, Bilal I; Abdul Halin, Izhal; Kawahito, Shoji; Sidek, Roslina M; Shafie, Suhaidi; Yunus, Nurul Amziah Md
2016-01-01
A review on CMOS delay lines with a focus on the most frequently used techniques for high-resolution delay step is presented. The primary types, specifications, delay circuits, and operating principles are presented. The delay circuits reported in this paper are used for delaying digital inputs and clock signals. The most common analog and digitally-controlled delay elements topologies are presented, focusing on the main delay-tuning strategies. IC variables, namely, process, supply voltage, temperature, and noise sources that affect delay resolution through timing jitter are discussed. The design specifications of these delay elements are also discussed and compared for the common delay line circuits. As a result, the main findings of this paper are highlighting and discussing the followings: the most efficient high-resolution delay line techniques, the trade-off challenge found between CMOS delay lines designed using either analog or digitally-controlled delay elements, the trade-off challenge between delay resolution and delay range and the proposed solutions for this challenge, and how CMOS technology scaling can affect the performance of CMOS delay lines. Moreover, the current trends and efforts used in order to generate output delayed signal with low jitter in the sub-picosecond range are presented.
NASA Astrophysics Data System (ADS)
Wang, Wen; Oh, Haekwan; Lee, Keekeun; Yoon, Sungjin; Yang, Sangsik
2009-06-01
In this paper, we present a novel microelectromechanical system-interdigital transducer (MEMS-IDT) surface acoustic wave (SAW) gyroscope with an 80 MHz central frequency on a 128° YX LiNbO3 wafer. The developed MEMS-IDT gyroscope is composed of a two-port SAW resonator, a dual delay line oscillator, and metallic dots. The SAW resonator provides a stable standing wave, and the vibrating metallic dot at an antinode of the standing wave induces the second SAW in the normal direction of its vibrating axis. The dual delay line oscillator detects the Coriolis force by comparing the resonant frequencies between two oscillators through the interference effect. The coupling of mode (COM) modeling was used to extract the optimal design parameters prior to fabrication. In the electrical testing by the network analyzer, the fabricated SAW resonator and delay lines showed low insertion loss and similar operation frequencies between a resonator and delay lines. When the device was rotated, the resonant frequency differences between two oscillators linearly varied owing to the Coriolis force. The obtained sensitivity was approximately 119 Hz deg-1 s-1 in the angular rate range of 0-1000 deg/s. Satisfactory linearity and superior directivity were also observed in the test.
Apparatus for simultaneously disreefing a centrally reefed clustered parachute system
Johnson, Donald W.
1988-01-01
A single multi-line cutter is connected to each of a cluster of parachutes by a separate short tether line that holds the parachutes, initially reefed by closed loop reefing lines, close to one another. The closed loop reefing lines and tether lines, one from each parachute, are disposed within the cutter to be simultaneously cut by its actuation when a central line attached between the payload and the cutter is stretched upon deployment of the cluster. A pyrotechnic or electronic time delay may be included in the cutter to delay the actual simultaneous cutting of all lines until the clustered parachutes attain a measure of stability prior to being disreefed. A second set of reefing lines and second tether lines may be provided for each parachute, to enable a two-stage, separately timed, step-by-step disreefing.
Apparatus for simultaneously disreefing a centrally reefed clustered parachute system
Johnson, D.W.
1988-06-21
A single multi-line cutter is connected to each of a cluster of parachutes by a separate short tether line that holds the parachutes, initially reefed by closed loop reefing lines, close to one another. The closed loop reefing lines and tether lines, one from each parachute, are disposed within the cutter to be simultaneously cut by its actuation when a central line attached between the payload and the cutter is stretched upon deployment of the cluster. A pyrotechnic or electronic time delay may be included in the cutter to delay the actual simultaneous cutting of all lines until the clustered parachutes attain a measure of stability prior to being disreefed. A second set of reefing lines and second tether lines may be provided for each parachute, to enable a two-stage, separately timed, step-by-step disreefing. 13 figs.
High Temperature Superconductivity Applications for Electronic Warfare and Microwave Systems
1990-05-01
instantaneous frequency measurement (IFM), as well as, switched delay lines for EW radar range deception and low loss, high resolution MMIC phase...Junction (JJ). This device has been demonstrated in LTSC and is used in very stable ( low noise ), frequency selective, oscillators and very low noise ...following HTSC components: 1) MMIC Filters 2) MMIC Delay Lines/Phase Shifters 3) Microwave Resonators 4) Antenna Feed Networks 5) Low Frequency Antennas 1
Jones, Jefferson Michael; Armstrong, Lori R
Drug-susceptibility testing (DST) of Mycobacterium tuberculosis is necessary for identifying drug-resistant tuberculosis, administering effective treatment regimens, and preventing the spread of drug-resistant tuberculosis. DST is recommended for all culture-confirmed cases of tuberculosis. We examined trends in delayed and unreported DST results in the Centers for Disease Control and Prevention's National Tuberculosis Surveillance System. We analyzed culture-confirmed tuberculosis cases reported to the National Tuberculosis Surveillance System during 1993-2014 for annual trends in initial DST reporting for first-line antituberculosis drugs and trends in on-time, delayed, and unreported results. We defined on-time reporting as DST results received during the same calendar year in which the patient's case was reported or ≤4 months after the calendar year ended and delayed reporting as DST results received after the calendar year. We compared cases with on-time, delayed, and unreported DST results by patient and tuberculosis program characteristics. The proportion of cases with reported results for all first-line antituberculosis drugs increased during 1993-2011. Reporting of pyrazinamide results was lower than reporting of other drugs. However, during 2000-2012, of 134 787 tuberculosis cases reported to the National Tuberculosis Surveillance System, reporting was on time for 125 855 (93.4%) cases, delayed for 5332 (4.0%) cases, and unreported for 3600 (2.7%) cases. Despite increases in the proportion of cases with on-time DST results, delayed and unreported results persisted. Carefully assessing causes for delayed and unreported DST results should lead to more timely reporting of drug-resistant tuberculosis.
Numerical modelling of multimode fibre-optic communication lines
DOE Office of Scientific and Technical Information (OSTI.GOV)
Sidelnikov, O S; Fedoruk, M P; Sygletos, S
The results of numerical modelling of nonlinear propagation of an optical signal in multimode fibres with a small differential group delay are presented. It is found that the dependence of the error vector magnitude (EVM) on the differential group delay can be reduced by increasing the number of ADC samples per symbol in the numerical implementation of the differential group delay compensation algorithm in the receiver. The possibility of using multimode fibres with a small differential group delay for data transmission in modern digital communication systems is demonstrated. It is shown that with increasing number of modes the strong couplingmore » regime provides a lower EVM level than the weak coupling one. (fibre-optic communication lines)« less
A Milestone for the VLT Interferometer
NASA Astrophysics Data System (ADS)
2000-10-01
Less than one month after "First Light" for the fourth 8.2-m YEPUN telescope ( ESO PR 18/00 ), another special moment occurred at ESO's Paranal Observatory. This time, it was the first truly "underground" event, in the 168-metre long Interferometric Tunnel that has been dug beneath the platform at the top of the mountain. As one staff member remarked on this occasion, it was something like "the first scheduled trip of the Paranal metro"! With the successful integration of the first Delay Line on Monday, September 25th, 2000, ESO has accomplished another important step towards the VLT Interferometer (VLTI). It will be followed by the integration of the second Delay Line by the end of November and the third is scheduled for February 2001; both are now in their final development phase in Europe. "VLTI First Light" is then expected to take place soon thereafter, by means of two small special telescopes ("siderostats"). The combination of the light beams from two of the 8.2-m Unit Telescopes will happen in mid-2001. The VLTI Delay Lines The VLTI Delay Lines form essential parts of this very complicated optical system. They serve to ensure that the light beams from several telescopes arrive in phase at the common interferometric focus. Details about how they function may be found in ESO PR 04/98. In order to achieve the necessary performance, ESO has worked with two Dutch contractors, Fokker Space and TNO-TPD - Netherlands Organization for Applied Scientific Research - Institute of Applied Physics , to arrive at a totally new Delay Line concept. Another Dutch participant in the VLTI project is the Nova-ESO VLTI Expertise Centre (NEVEC) , cf. ESO PR 14/00. The installation at Paranal The last twelve months have been very busy for the integration team, with much preparatory work at the VLTI buildings for the final installation of the Delay Line systems. The assembly of the translation mechanisms for the first two Delay Lines in the tunnel started in mid-2000. This included the alignment of their rails and supports to the extreme accuracy of about 0.25 mm over a total distance of 66.7 metres ( PR Photos 26a-b/00 ). To achieve such an unusually high precision, ESO - in collaboration with the French company FOGALE - developed a measurement system that is based on the water-level principle. The delicate assembly and alignment of the critical sub-systems of the Delay Line were undertaken with the support of Fokker Space and TPD/TNO ( PR Photo 26e/00 ). Also for this, state-of-the-art methods were required in order to ensure a stringent performance of the system. This includes optical alignment of the optics with an accuracy at the arcsec level and positioning of the linear motors at the 0.01 mm (10 µm) level. The Delay Line is one of the key systems in the VLT Interferometer. It is responsible for the compensation of the length of the optical path that is different from the individual telescopes. Extreme accuracy needed In the case of the VLT, this accuracy of the path length compensation must be within a tolerance of only 0.05 µm (0.00005 mm) over a distance of 120 metres. The present concept by ESO and the Dutch contractors is based on a retro-reflector (a "Cat's Eye") that is fixed on a carriage that runs on two stainless steel rails ( PR Photos 26c-d/00 ). The motion on these rails is performed by a 60 metres linear motor and a piezo-transducer element. They are controlled by a laser metrology system that measures the instantaneous distances betwen the mirrors with the required accuracy. This carriage is 2.5 metres long and weighs 250 kg. The total friction force is less than 50 grammes, thanks to the extreme accuracy of the rail alignment and special ball bearings. Because of this, the total power required for the Delay Line operation is only about 15 W. The mirrors of the retro-reflector are made of aluminium by REOSC (France). They have been coated with a single layer of gold for the best possible reflection at infrared wavelengths. This is the caption to ESO PR Photos 26a-e/00 . They may be reproduced, if credit is given to the European Southern Observatory. Note, however, that since these photos were electronically recorded and were primarily obtained to document the ongoing activities at Paranal, they are not of full professional quality for photographic reproduction.
Gong, Zhaoyuan; Walls, Jamie D
2018-02-01
Delayed-acquisition, which is a common technique for improving spectral resolution in Fourier transform based spectroscopies, typically relies upon differences in T 2 relaxation rates that are often due to underlying differences in dynamics and/or complexities of the spin systems being studied. After an acquisition delay, the broad signals from fast T 2 -relaxing species are more suppressed relative to the sharp signals from slow T 2 -relaxing species. In this paper, an alternative source of differential "dephasing" under delayed-acquisition is demonstrated that is based solely upon the mathematical properties of the line shape and is independent of the underlying spin dynamics and/or complexity. Signals associated with frequencies where the line shape either changes sharply and/or is non-differentiable at some finite order dephase at a much slower rate than those signals associated with frequencies where the line shape is smooth. Experiments employing delayed-acquisition to study interfaces in biphasic samples, to measure spatially-dependent longitudinal relaxation, and to highlight sharp features in NMR spectra are presented. Copyright © 2017 Elsevier Inc. All rights reserved.
NASA Astrophysics Data System (ADS)
Gong, Zhaoyuan; Walls, Jamie D.
2018-02-01
Delayed-acquisition, which is a common technique for improving spectral resolution in Fourier transform based spectroscopies, typically relies upon differences in T2 relaxation rates that are often due to underlying differences in dynamics and/or complexities of the spin systems being studied. After an acquisition delay, the broad signals from fast T2 -relaxing species are more suppressed relative to the sharp signals from slow T2 -relaxing species. In this paper, an alternative source of differential "dephasing" under delayed-acquisition is demonstrated that is based solely upon the mathematical properties of the line shape and is independent of the underlying spin dynamics and/or complexity. Signals associated with frequencies where the line shape either changes sharply and/or is non-differentiable at some finite order dephase at a much slower rate than those signals associated with frequencies where the line shape is smooth. Experiments employing delayed-acquisition to study interfaces in biphasic samples, to measure spatially-dependent longitudinal relaxation, and to highlight sharp features in NMR spectra are presented.
Choi, Eunseo; Na, Jihoon; Ryu, Seon; Mudhana, Gopinath; Lee, Byeong
2005-02-21
We have implemented an all-fiber optical delay line using two linearly chirped fiber Bragg gratings cascaded in reverse order and all-fiber optics components. The features of the proposed all-fiber based technique for variable delay line are discussed theoretically and demonstrated experimentally. The non-invasive cross-sectional images of biomedical samples as well as a transparent glass plate obtained with implemented all-fiber delay line having the axial resolution of 100 mum and the dynamic range of 50dB are presented to validates the imaging performance and demonstrate the feasibility of the delay line for optical coherence tomography.
NASA Astrophysics Data System (ADS)
Cho, Young; Kumar, Akhil; Xu, Song; Zou, Jun
2017-03-01
Recent studies have shown that micromachined silicon acoustic delay lines can provide a promising solution to achieve real-time photoacoustic tomography without the need for complex transducer arrays and data acquisition electronics. However, as its length increases to provide longer delay time, the delay line becomes more vulnerable to structural instability due to reduced mechanical stiffness. In addition, the small cross-section area of the delay line results in a large acoustic acceptance angle and therefore poor directivity. To address these two issues, this paper reports the design, fabrication, and testing of a new silicon acoustic delay line enhanced with 3D printed polymer micro linker structures. First, mechanical deformation of the silicon acoustic delay line (with and without linker structures) under gravity was simulated by using finite element method. Second, the acoustic crosstalk and acoustic attenuation caused by the polymer micro linker structures were evaluated with both numerical simulation and ultrasound transmission testing. The result shows that the use of the polymer micro linker structures significantly improves the structural stability of the silicon acoustic delay lines without creating additional acoustic attenuation and crosstalk. In addition, a new tapered design for the input terminal of the delay line was also investigate to improve its acoustic directivity by reducing the acoustic acceptance angle. These two improvements are expected to provide an effective solution to eliminate current limitations on the achievable acoustic delay time and out-of-plane imaging resolution of micromachined silicon acoustic delay line arrays.
Mark 3 VLBI system: Tropospheric calibration subsystems
NASA Technical Reports Server (NTRS)
Resch, G. M.
1980-01-01
Tropospheric delay calibrations are implemented in the Mark 3 system with two subsystems. Estimates of the dry component of tropospheric delay are provided by accurate barometric data from a subsystem of surface meteorological sensors (SMS). An estimate of the wet component of tropospheric delay is provided by a water vapor radiometer (WVR). Both subsystems interface directly to the ASCII Transceiver bus of the Mark 3 system and are operated by the control computer. Seven WVR's under construction are designed to operate in proximity to a radio telescope and can be commanded to point along the line-of-sight to a radio source. They should provide a delay estimate that is accurate to the + or - 2 cm level.
Performances of a date dissemination code on telephone lines using commercial modems
NASA Technical Reports Server (NTRS)
Cordara, F.; Pettiti, V.; Quasso, R.; Rubiola, E.
1993-01-01
A coded time/date information dissemination system (CTD), based on telephone lines and commercial modems, is now in its experimental phase in Italy at IEN. This service, born from a cooperation with other metrological laboratories (TUG, Austria, SNT, Sweden, VSL, The Netherlands), represents an attempt towards an European standardization. Some results of an experimental analysis in which a few modems were tested, both in laboratory conditions and connected to the telephone network, in order to evaluate the timing capability of the system are given. When the system is used in a one-way mode, in many practical cases the modems delay turns out to be the main factor which limits the accuracy, even more than the telephone line delays. If the two-way mode is used, the modems asymmetry, i.e., the delay difference between transmission and reception, is almost always the most important source of uncertainty, provided the link is not including a space segment. Comparing the widely used V.22 modems to the old V.21 ones, the latters turn out to be better both in delay time (30-100 ms V.22, and 7-15 ms V.21) and asymmetry (10-50 micro-s V.22, and 10 ms V.22). Time transfer accuracies of 10 micron-s (same turn) to 100 micro-s (long distance calls) were obtained in two-way mode with commercial V.21 modems.
Swept Frequency Laser Metrology System
NASA Technical Reports Server (NTRS)
Zhao, Feng (Inventor)
2010-01-01
A swept frequency laser ranging system having sub-micron accuracy that employs multiple common-path heterodyne interferometers, one coupled to a calibrated delay-line for use as an absolute reference for the ranging system. An exemplary embodiment uses two laser heterodyne interferometers to create two laser beams at two different frequencies to measure distance and motions of target(s). Heterodyne fringes generated from reflections off a reference fiducial X(sub R) and measurement (or target) fiducial X(sub M) are reflected back and are then detected by photodiodes. The measured phase changes Delta phi(sub R) and Delta phi (sub m) resulting from the laser frequency swept gives target position. The reference delay-line is the only absolute reference needed in the metrology system and this provides an ultra-stable reference and simple/economical system.
NASA Astrophysics Data System (ADS)
Cho, Y.; Kumar, A.; Xu, S.; Zou, J.
2016-10-01
Recent studies have shown that micromachined silicon acoustic delay lines can provide a promising solution to achieve real-time photoacoustic tomography without the need for complex transducer arrays and data acquisition electronics. To achieve deeper imaging depth and wider field of view, a longer delay time and therefore delay length are required. However, as the length of the delay line increases, it becomes more vulnerable to structural instability due to reduced mechanical stiffness. In this paper, we report the design, fabrication, and testing of a new silicon acoustic delay line enhanced with 3D printed polymer micro linker structures. First, mechanical deformation of the silicon acoustic delay line (with and without linker structures) under gravity was simulated by using finite element method. Second, the acoustic crosstalk and acoustic attenuation caused by the polymer micro linker structures were evaluated with both numerical simulation and ultrasound transmission testing. The result shows that the use of the polymer micro linker structures significantly improves the structural stability of the silicon acoustic delay lines without creating additional acoustic attenuation and crosstalk. In addition, the improvement of the acoustic acceptance angle of the silicon acoustic delay lines was also investigated to better suppress the reception of unwanted ultrasound signals outside of the imaging plane. These two improvements are expected to provide an effective solution to eliminate current limitations on the achievable acoustic delay time and out-of-plane imaging resolution of micromachined silicon acoustic delay line arrays.
Clemensen, R.E.
1959-11-01
An electrically variable time delay line is described which may be readily controlled simuitaneously with variable impedance matching means coupied thereto such that reflections are prevented. Broadly, the delay line includes a signal winding about a magnetic core whose permeability is electrically variable. Inasmuch as the inductance of the line varies directly with the permeability, the time delay and characteristic impedance of the line both vary as the square root of the permeability. Consequently, impedance matching means may be varied similariy and simultaneously w:th the electrically variable permeability to match the line impedance over the entire range of time delay whereby reflections are prevented.
Terrestrial Planet Finder cryogenic delay line development
NASA Technical Reports Server (NTRS)
Smythe, Robert F.; Swain, Mark R.; Alvarez-Salazar, Oscar; Moore, James D.
2004-01-01
Delay lines provide the path-length compensation that makes the measurement of interference fringes possible. When used for nulling interferometry, the delay line must control path-lengths so that the null is stable and controlled throughout the measurement. We report on a low noise, low disturbance, and high bandwidth optical delay line capable of meeting the TPF interferometer optical path length control requirements at cryogenic temperatures.
NASA Astrophysics Data System (ADS)
Horne, Keith D.; Agn Storm Team
2015-01-01
Two-dimensional velocity-delay maps of AGN broad emission line regions can be recovered by modelling observations of reverberating emission-line profiles on the assumption that the line profile variations are driven by changes in ionising radiation from a compact source near the black hole. The observable light travel time delay resolves spatial structure on iso-delay paraboloids, while the doppler shift resolves kinematic structure along the observer's line-of-sight. Velocity-delay maps will be presented and briefly discussed for the Lyman alpha, CIV and Hbeta line profiles based on the HST and ground-based spectrophotometric monitoring of NGC 5548 during the 2014 AGN STORM campaign.
Near-toll quality digital speech transmission in the mobile satellite service
NASA Technical Reports Server (NTRS)
Townes, S. A.; Divsalar, D.
1986-01-01
This paper discusses system considerations for near-toll quality digital speech transmission in a 5 kHz mobile satellite system channel. Tradeoffs are shown for power performance versus delay for a 4800 bps speech compression system in conjunction with a 16 state rate 2/3 trellis coded 8PSK modulation system. The suggested system has an additional 150 ms of delay beyond the propagation delay and requires an E(b)/N(0) of about 7 dB for a Ricean channel assumption with line-of-sight to diffuse component ratio of 10 assuming ideal synchronization. An additional loss of 2 to 3 dB is expected for synchronization in fading environment.
ESO and Fokker Space Sign Contract about VLTI Delay Line
NASA Astrophysics Data System (ADS)
1998-03-01
The European Southern Observatory is building the world's largest optical telescope, the Very Large Telescope (VLT) , at the ESO Paranal Observatory in Chile. The VLT consists of four 8.2-m unit telescopes and several smaller, moveable Auxiliary Telescopes. When coupled as the giant VLT Interferometer (VLTI) , they will together provide the sharpest images ever obtained by any optical telescope. It will in principle be able to see an astronaut on the surface of the Moon, 400,000 km away. The VLTI Delay Lines Fokker Space (Leiden, The Netherlands) has been awarded a contract for the delivery of the Delay Line of the VLTI. This is a mechanical-optical system that will compensate the optical path differences of the light beams from the individual telescopes. Such a system is necessary to ensure that the light from all telescopes arrive in the same phase at the focal point of the interferometer. Otherwise, the very sharp interferometric images cannot be obtained. ESO PR Photo 08/98 [JPEG, 102k] Schematic representation of the VLTI Delay Line, showing the retro-reflector on its moving base. For more details, please consult the technical explanation below. This highly accurate system will be developed in close co-operation with the Dutch institute TNO-TPD (Netherlands Organization for Applied Scientific Research - Institute of Applied Physics) . The most innovative feature of the Delay Line is the new control strategy, a two-stage control system, based on linear motor technology, combined with high accuracy piezo-electric control elements. This enables the system to position the so-called cat's eye reflector system with an accuracy of only a few nanometers (millionth of a millimetre (nm)) over a stroke length of 60 metres. Within radio astronomy, interferometric techniques have been applied by Dutch astronomers since many years. They will now be able to contribute with their extensive knowledge of such systems to the next generation of astronomical interferometric instruments within the present collaboration. About Fokker Space Fokker Space is the largest company in the Dutch space industry. It is based in Leiden, has 481 employees and an operating income of 220 million Netherlands Guilders in 1996. Fokker Space is mainly active in the field of solar arrays, launcher structures, thermal products, instruments and simulators. It also plays a key role in the development of robotics and is responsible as a prime contractor for the European Robotics Arm (ERA) to be used on the International Space Station. Fokker Space is well embedded in the Dutch aerospace infrastructure, thanks to close relations with the Dutch Space Agency (NIVR) , the National Aerospace Laboratory (NLR) , the Delft University of Technology and other Dutch space industries and institutes like TNO-TPD (Netherlands Organization for Applied Scientific Research - Institute of Applied Physics) . Fokker Space has also entered into strategic partnerships in Europe, Russia and North America. These facts, combined with the long lasting relation with the European Space Agency ESA and with the Dutch Government imply that Fokker Space has secured a solid base for continuation of its business far into the next millennium. Some technical details about the VLTI Delay Line The VLT Delay Line forms an essential part of the VLT Interferometer (VLTI) . It represents the current limit of high technology in this field and includes many innovative features. Some of the technical details are given below. In order to enable a useful combination of the light beams from the individual telescopes of the VLT (that is, to produce interferometric fringes at the focal point), the optical path length differences must be corrected by the Delay Line system. These differences are caused by: * the static geometric path length difference between the telescopes in a certain configuration; * the diurnal motion of the astronomical source during observation due to Earth's rotation; and * the rapid path length variations due to atmospheric disturbances and/or mechanical vibrations along the optical path length. The VLTI Delay Line system consists of a retro-reflector mounted on a moving base. The optical design of this `Cat's Eye' is of the Ritchey-Chretien type that reflects the light very effectively. For this particular application, the `Cat's Eye' is not a corner cube with 3 perpendicular mirrors as is the case in the reflectors on cars and bicycles; it is in fact a telescope with a mirror at the focus that sends a light beam back in a direction parallel to the one it came from. The moving base enables the Cat's Eye to travel along a 60 metres long rail track, thereby providing optical path difference corrections of up to 120 metres, as required for the VLT telescope configurations at Paranal. The necessary, rapid path length corrections are performed by a fine positioning loop in which a piezo crystal (mounted on the backside of the Variable Curvature Mirror M3) is used to correct the fast optical path variations as measured by a Fringe Sensing Unit (FSU). The latter provides a signal to the Delay Line system via a fast link to the Delay Line Local Control Unit. An optical datalink to the Cat's Eye on the carriage ensures the transfer of data to the Piezo controller. The carriage is driven by a Linear Induction Motor. The coils for the motor are mounted on the floor of the Delay Line Long Support Bench and the magnets are mounted on the bottom of the carriage. The metrology system (to measure the carriage position) consists of a laser-interferometer whose beam follows the same path as the light beams from the telescopes via the Cat's Eye. The main design parameters are shown here: Optical Path range above 120 m Optical Path resolution better than 20 nm Optical Path stability better than 14 nm over any 0.01 sec (in the visible spectral range) better than 50 nm over any 0.05 sec (in Near-IR spectral range) better than 225 nm over any 0.3 sec (in Thermal-IR spectral range) Absolute position repeatability 50 micron (over full length - 60 metres) 1 micron (over observation length - 3 metres) Maximum velocity: 0.5 m/sec Maximum velocity errors 1 micron/sec Maximum power dissipation 15 Watts Note: [1] This Press Release is issued jointly by ESO and Fokker Space on the occasion of the signature of the contract for the VLTI Delay System which takes place at Fokker Space in Leiden (The Netherlands) today. How to obtain ESO Press Information ESO Press Information is made available on the World-Wide Web (URL: http://www.eso.org ). ESO Press Photos may be reproduced, if credit is given to the European Southern Observatory.
Employing TDMA Protocol in Neural Nanonetworks in Case of Neuron Specific Faults.
Tezcan, Hakan; Oktug, Sema F; Kök, Fatma Neşe
2015-09-01
Many neurodegenerative diseases arise from the malfunctioning neurons in the pathway where the signal is carried. In this paper, we propose neuron specific TDMA/multiplexing and demultiplexing mechanisms to convey the spikes of a receptor neuron over a neighboring path in case of an irreversible path fault existing in its original path. The multiplexing mechanism depends on neural delay box (NDB) which is composed of a relay unit and a buffering unit. The relay unit can be realized as a nanoelectronic device. The buffering unit can be implemented either via neural delay lines as employed in optical switching systems or via nanoelectronic delay lines, i.e., delay flip flops. Demultiplexing is realized by a demultiplexer unit according to the time slot assignment information. Besides, we propose the use of neural interfaces in the NDBs and the demultiplexer unit for detecting and stimulating the generation of spikes. The objective of the proposed mechanisms is to substitute a malfunctioning path, increase the number of spikes delivered and correctly deliver the spikes to the intended part of the somatosensory cortex. The results demonstrate that significant performance improvement on the successively delivered number of spikes is achievable when delay lines are employed as neural buffers in NDBs.
1st Order Modeling of a SAW Delay Line using MathCAD(Registered)
NASA Technical Reports Server (NTRS)
Wilson, William C.; Atkinson, Gary M.
2007-01-01
To aid in the development of SAW sensors for Integrated Vehicle Health Monitoring applications, a first order model of a SAW Delay line has been created using MathCadA. The model implements the Impulse Response method to calculate the frequency response, impedance, and insertion loss. This paper presents the model and the results from the model for a SAW delay line design. Integrated Vehicle Health Monitoring (IVHM) of aerospace vehicles requires rugged sensors having reduced volume, mass, and power that can be used to measure a variety of phenomena. Wireless systems are preferred when retro-fitting sensors onto existing vehicles [1]. Surface Acoustic Wave (SAW) devices are capable of sensing: temperature, pressure, strain, chemical species, mass loading, acceleration, and shear stress. SAW technology is low cost, rugged, lightweight, and extremely low power. Passive wireless sensors have been developed using SAW technology. For these reasons new SAW sensors are being investigated for aerospace applications.
NASA Technical Reports Server (NTRS)
Wilson, William C.; Atkinson, Gary M.
2007-01-01
Integrated Vehicle Health Monitoring (IVHM) of aerospace vehicles requires rugged sensors having reduced volume, mass, and power that can be used to measure a variety of phenomena. Wireless systems are preferred when retro-fitting sensors onto existing vehicles. Surface Acoustic Wave (SAW) devices are capable of sensing: temperature, pressure, strain, chemical species, mass loading, acceleration, and shear stress. SAW technology is low cost, rugged, lightweight, and extremely low power. To aid in the development of SAW sensors for IVHM applications, a first order model of a SAW Delay line has been created.
Device For Trapping Laser Pulses In An Optical Delay Line
Yu, David U. L.; Bullock, Donald L.
1997-12-23
A device for maintaining a high-energy laser pulse within a recirculating optical delay line for a period time to optimize the interaction of the pulse with an electron beam pulse train comprising closely spaced electron micropulses. The delay line allows a single optical pulse to interact with many of the electron micropulses in a single electron beam macropulse in sequence and for the introduction of additional optical pulses to interact with the micropulses of additional electron beam macropulses. The device comprises a polarization-sensitive beam splitter for admitting an optical pulse to and ejecting it from the delay line according to its polarization state, a Pockels cell to control the polarization of the pulse within the delay line for the purpose of maintaining it within the delay line or ejecting it from the delay line, a pair of focusing mirrors positioned so that a collimated incoming optical pulse is focused by one of them to a focal point where the pulse interacts with the electron beam and then afterwards the pulse is recollimated by the second focusing mirror, and a timing device which synchronizes the introduction of the laser pulse into the optical delay line with the arrival of the electron macropulse at the delay line to ensure the interaction of the laser pulse with a prescribed number of electron micropulses in sequence. In a first embodiment of the invention, the principal optical elements are mounted with their axes collinear. In a second embodiment, all principal optical elements are mounted in the configuration of a ring.
Li, Y L; Xu, D L; Fu, Y M; Zhou, J X
2011-09-01
This paper presents a systematic study on the stability of a two-dimensional vibration isolation floating raft system with a time-delayed feedback control. Based on the generalized Sturm criterion, the critical control gain for the delay-independent stability region and critical time delays for the stability switches are derived. The critical conditions can provide a theoretical guidance of chaotification design for line spectra reduction. Numerical simulations verify the correctness of the approach. Bifurcation analyses reveal that chaotification is more likely to occur in unstable region defined by these critical conditions, and the stiffness of the floating raft and mass ratio are the sensitive parameters to reduce critical control gain.
Kondalkar, Vijay V; Li, Xiang; Park, Ikmo; Yang, Sang Sik; Lee, Keekeun
2018-02-05
A chipless, wireless current sensor system was developed using a giant magnetoimpedance (GMI) magnetic sensor and one-port surface acoustic wave (SAW) reflective delay line for real-time power monitoring in a current-carrying conductor. The GMI sensor has a high-quality crystalline structure in each layer, which contributes to a high sensitivity and good linearity in a magnetic field of 3-16 Oe. A 400 MHz RF energy generated from the interdigital transducer (IDT)-type reflector on the one-port SAW delay line was used as an activation source for the GMI magnetic sensor. The one-port SAW delay line replaces the presently existing transceiver system, which is composed of thousands of transistors, thus enabling chipless and wireless operation. We confirmed a large variation in the amplitude of the SAW reflection peak with a change in the impedance of the GMI sensor caused by the current flow through the conductor. Good linearity and sensitivity of ~0.691 dB/A were observed for currents in the range 1-12 A. Coupling of Mode (COM) modeling and impedance matching analysis were also performed to predict the device performance in advance and these were compared with the experimental results.
Magnonic Crystal as a Delay Line for Low-Noise Auto-Oscillator
2015-05-12
Magnonic crystal as a delay line for low-noise auto-oscillator Elena Bankowski and Thomas Meitzler U.S. Army TARDEC, Warren, Michigan 48397, USA...authors propose to use the magnonic crystal patterned on the YIG magnetic film as an efficient delay line in the feedback loop of tunable auto-oscillator...increasing the thickness of such delay line as compare to the YIG film with no pattern. In turn, use of this magnonic crystal opens a way to improve
The DARWIN breadboard cryogenic optical delay line
NASA Astrophysics Data System (ADS)
van den Dool, T. C.; Gielesen, W.; Kamphues, F.; Loix, N.; Kooijman, P. P.; de Vries, C.; van Weers, H.; Fleury, K.; Stockman, Y.; Velsink, G.; Benoit, J.; Poupinet, A.; Sève, F.
2017-11-01
TNO, in cooperation with Micromega-Dynamics, SRON, Dutch Space and CSL, has designed a compact breadboard cryogenic delay line (figure 1) for use in future space interferometry missions. The work is performed under ESA contract 17.747/03 in preparation for the DARWIN mission. The breadboard (BB) delay line is representative of a flight mechanism. The delay line has a single stage voice coil actuator for Optical Path Difference (OPD) control, driving a twomirror cat's eye. Magnetic bearings provide frictionless and wear free operation with zero-hysteresis. The design of the BB delay line has been completed. The development test program, including operation at 100 K has been completed. The verification test programme is currently being carried out and will include functional testing at 40 K.
NASA Astrophysics Data System (ADS)
Andreev, R. B.; Butylkin, V. S.; Evtiushkin, V. A.; Fisher, P. S.; Khabarov, V. V.
1983-03-01
The threshold of stimulated Raman scattering was lowered by filling an optical delay line with hydrogen. Pumping was by a tunable neodymium laser. Lens-prism combinations were used as phase correctors in the delay line. The dependences of the energy of the Stokes component on the pump energy determined experimentally for different numbers of transits through the delay line were compared with the results of a calculation allowing for the losses in the components of this line. When the frequency conversion was by a factor of at least 2 and the tuning range was wide (tens of percent), the optimal performance was obtained from the optical delay line when total-internal-reflection prisms and lenses were combined in a single component and oriented at the Brewster angle.
NASA Astrophysics Data System (ADS)
Andreev, R. B.; Butylkin, V. S.; Evtyushkin, V. A.; Fisher, P. S.; Khabarov, V. V.
1983-03-01
The threshold of stimulated Raman scattering was lowered by filling an optical delay line with hydrogen. Pumping was by a tunable neodymium laser. Lens-prism combinations were used as phase correctors in the delay line. The dependences of the energy of the Stokes component on the pump energy determined experimentally for different numbers of transits through the delay line were compared with the results of a calculation allowing for the losses in the components of this line. When the frequency conversion was by a factor of at least 2 and the tuning range was wide (tens of percent), the optimal performance was obtained from the optical delay line when total-internal-reflection prisms and lenses were combined in a single component and oriented at the Brewster angle.
Manipulating flexible parts using a teleoperated system with time delay: An experiment
NASA Technical Reports Server (NTRS)
Kotoku, T.; Takamune, K.; Tanie, K.; Komoriya, K.; Matsuhira, N.; Asakura, M.; Bamba, H.
1994-01-01
This paper reports experiments involving the handling of flexible parts (e.g. wires) when using a teleoperated system with time delay. The task is principally a peg-in-hole task involving the wrapping of a wire around two posts on the task-board. It is difficult to estimate the effects of the flexible parts; therefore, on-line teleoperation is indispensable for this class of unpredictable task. We first propose a teleoperation system based on the predictive image display, then describe an experimental teleoperation testbed with a four second transmission time delay. Finally, we report on wire handling operations that were performed to evaluate the performance of this system. Those experiments will contribute to future advanced experiments for the MITI ETS-7 mission.
Analysis of Delays in Transmitting Time Code Using an Automated Computer Time Distribution System
1999-12-01
jlevine@clock. bldrdoc.gov Abstract An automated computer time distribution system broadcasts standard tune to users using computers and modems via...contributed to &lays - sofhareplatform (50% of the delay), transmission speed of time- codes (25OA), telephone network (lS%), modem and others (10’4). The... modems , and telephone lines. Users dial the ACTS server to receive time traceable to the national time scale of Singapore, UTC(PSB). The users can in
Acute ethanol does not always affect delay discounting in rats selected to prefer or avoid ethanol.
Wilhelm, Clare J; Mitchell, Suzanne H
2012-01-01
The purpose of this study was to determine whether animals predisposed to prefer alcohol possess an altered acute response to alcohol on a delay discounting task relative to animals predisposed to avoid alcohol. We used rats selected to prefer or avoid alcohol to assess whether genotype moderates changes in delay discounting induced by acute ethanol exposure. Selectively bred rat lines of Sardinian alcohol-preferring (sP; n = 8) and non-preferring (sNP; n = 8) rats, and alko alcohol (AA, n = 8) and alko non-alcohol (ANA, n = 8) rats were trained in an adjusting amount task to assess delay discounting. There were no significant effects of line on baseline discounting; however, both lines of alcohol-preferring rats exhibit slowed reaction times. Acute ethanol (0, 0.25, 0.5 g/kg) treatment also had no effect on delay discounting in any of the selectively bred rat lines. Our data indicate that in these lines of animals, alcohol preference or avoidance has no impact on delay discounting following acute ethanol exposure. It is possible that other genetic models or lines may be differentially affected by alcohol and exhibit qualitatively and quantitatively different responses in delay discounting tasks.
Time-resolved coherent Raman spectroscopy by high-speed pump-probe delay scanning.
Domingue, S R; Winters, D G; Bartels, R A
2014-07-15
Using a spinning window pump-probe delay scanner, we demonstrate a means of acquiring time-resolved vibrational spectra at rates up to 700 Hz. The time-dependent phase shift accumulated by the probe pulse in the presence of a coherently vibrating sample gives rise to a Raman-induced frequency shifting readily detectable in a balanced detector. This rapid delay scanning system represents a 23-fold increase in averaging speed and is >10× faster than state-of-the-art voice coil delay lines. These advancements make pump-probe spectroscopy a more practical means of imaging complex media.
NASA Astrophysics Data System (ADS)
Sabri, Nursalwanie Mohd; Haider, Zuhaib; Tufail, Kashif; Imran, Muhammad; Ali, Jalil
2017-03-01
Laser-induced plasma spectroscopy is performed to determine the elemental compositions of manganese and zinc in potassium bromide (KBr) matrix. This work has utilized Q-switched Nd:YAG laser installed in LIBS2500plus system at fundamental wavelength. The pelletized sample were ablated in air with maximum laser energy of 650 mJ for different gate delays ranging from 0-18 µs. The spectra of samples are obtained for five different compositions containing preferred spectral lines. The intensity of spectral line is observed at its maximum at a gate-delay 0.83 µs and subsequently decayed exponentially with the increasing of gate delay. Maximum signal-to-background ratio of Mn and Zn were found at gate delays of 7.92 and 7.50 µs, respectively. Initial calibration curves show bad data fitting, whereas the locally normalized intensity for both spectral lines shows enhancement since it is more linearly regressed. This study will give a better understanding in studying the plasma emission and the spectra analysis. At the request of all authors of the paper, and with the agreement of the Proceedings Editor, an updated version of this article was published on 24 May 2017.
Distortion management in slow-light pulse delay.
Stenner, Michael D; Neifeld, Mark A; Zhu, Zhaoming; Dawes, Andrew M C; Gauthier, Daniel J
2005-12-12
We describe a methodology to maximize slow-light pulse delay subject to a constraint on the allowable pulse distortion. We show that optimizing over a larger number of physical variables can increase the distortion-constrained delay. We demonstrate these concepts by comparing the optimum slow-light pulse delay achievable using a single Lorentzian gain line with that achievable using a pair of closely-spaced gain lines. We predict that distortion management using a gain doublet can provide approximately a factor of 2 increase in slow-light pulse delay as compared with the optimum single-line delay. Experimental results employing Brillouin gain in optical fiber confirm our theoretical predictions.
NASA Astrophysics Data System (ADS)
Wang, Yonggang; Liu, Chong
2016-10-01
Field programmable gate arrays (FPGAs) manufactured with more advanced processing technology have faster carry chains and smaller delay elements, which are favorable for the design of tapped delay line (TDL)-style time-to-digital converters (TDCs) in FPGA. However, new challenges are posed in using them to implement TDCs with a high time precision. In this paper, we propose a bin realignment method and a dual-sampling method for TDC implementation in a Xilinx UltraScale FPGA. The former realigns the disordered time delay taps so that the TDC precision can approach the limit of its delay granularity, while the latter doubles the number of taps in the delay line so that the TDC precision beyond the cell delay limitation can be expected. Two TDC channels were implemented in a Kintex UltraScale FPGA, and the effectiveness of the new methods was evaluated. For fixed time intervals in the range from 0 to 440 ns, the average RMS precision measured by the two TDC channels reaches 5.8 ps using the bin realignment, and it further improves to 3.9 ps by using the dual-sampling method. The time precision has a 5.6% variation in the measured temperature range. Every part of the TDC, including dual-sampling, encoding, and on-line calibration, could run at a 500 MHz clock frequency. The system measurement dead time is only 4 ns.
Advanced optical delay line demonstrator
NASA Astrophysics Data System (ADS)
van den Dool, Teun; Kamphues, Fred; Fouss, B.; Henrioulle, K.; Hogenhuis, Harm
2004-09-01
TNO TPD, in cooperation with Micromega-Dynamics and Dutch Space, has designed an advanced Optical Delay Line (ODL) for use in future ground based and space interferometry missions. The work is performed under NIVR contract in preparation for GENIE and DARWIN. Using the ESO PRIMA DDL requirements as a baseline, the delay line can be used for PRIMA and GENIE without any modifications. The delay line design is modular and flexible, which makes scaling for other applications a relatively easy task. The ODL has a single linear motor actuator for Optical Path Difference (OPD) control, driving a two-mirror cat"s eye with SiC mirrors and CFRP structure. Magnetic bearings provide frictionless and wear free operation with zerohysteresis. The delay line is currently being assembled and will be subjected to a comprehensive test program in the second half of 2004.
Optical sampling by laser cavity tuning.
Hochrein, Thomas; Wilk, Rafal; Mei, Michael; Holzwarth, Ronald; Krumbholz, Norman; Koch, Martin
2010-01-18
Most time-resolved optical experiments rely either on external mechanical delay lines or on two synchronized femtosecond lasers to achieve a defined temporal delay between two optical pulses. Here, we present a new method which does not require any external delay lines and uses only a single femtosecond laser. It is based on the cross-correlation of an optical pulse with a subsequent pulse from the same laser. Temporal delay between these two pulses is achieved by varying the repetition rate of the laser. We validate the new scheme by a comparison with a cross-correlation measurement carried out with a conventional mechanical delay line.
Kohler, Daniel D.; Thompson, Blaise J.; Wright, John C.
2017-08-31
Ultrafast spectroscopy is often collected in the mixed frequency/time domain, where pulse durations are similar to system dephasing times. In these experiments, expectations derived from the familiar driven and impulsive limits are not valid. This work simulates the mixed-domain four-wave mixing response of a model system to develop expectations for this more complex field-matter interaction. We also explore frequency and delay axes. We show that these line shapes are exquisitely sensitive to excitation pulse widths and delays. Near pulse overlap, the excitation pulses induce correlations that resemble signatures of dynamic inhomogeneity. We describe these line shapes using an intuitive picturemore » that connects to familiar field-matter expressions. We develop strategies for distinguishing pulse-induced correlations from true system inhomogeneity. Our simulations provide a foundation for interpretation of ultrafast experiments in the mixed domain.« less
Neural node network and model, and method of teaching same
Parlos, A.G.; Atiya, A.F.; Fernandez, B.; Tsai, W.K.; Chong, K.T.
1995-12-26
The present invention is a fully connected feed forward network that includes at least one hidden layer. The hidden layer includes nodes in which the output of the node is fed back to that node as an input with a unit delay produced by a delay device occurring in the feedback path (local feedback). Each node within each layer also receives a delayed output (crosstalk) produced by a delay unit from all the other nodes within the same layer. The node performs a transfer function operation based on the inputs from the previous layer and the delayed outputs. The network can be implemented as analog or digital or within a general purpose processor. Two teaching methods can be used: (1) back propagation of weight calculation that includes the local feedback and the crosstalk or (2) more preferably a feed forward gradient decent which immediately follows the output computations and which also includes the local feedback and the crosstalk. Subsequent to the gradient propagation, the weights can be normalized, thereby preventing convergence to a local optimum. Education of the network can be incremental both on and off-line. An educated network is suitable for modeling and controlling dynamic nonlinear systems and time series systems and predicting the outputs as well as hidden states and parameters. The educated network can also be further educated during on-line processing. 21 figs.
Neural node network and model, and method of teaching same
Parlos, Alexander G.; Atiya, Amir F.; Fernandez, Benito; Tsai, Wei K.; Chong, Kil T.
1995-01-01
The present invention is a fully connected feed forward network that includes at least one hidden layer 16. The hidden layer 16 includes nodes 20 in which the output of the node is fed back to that node as an input with a unit delay produced by a delay device 24 occurring in the feedback path 22 (local feedback). Each node within each layer also receives a delayed output (crosstalk) produced by a delay unit 36 from all the other nodes within the same layer 16. The node performs a transfer function operation based on the inputs from the previous layer and the delayed outputs. The network can be implemented as analog or digital or within a general purpose processor. Two teaching methods can be used: (1) back propagation of weight calculation that includes the local feedback and the crosstalk or (2) more preferably a feed forward gradient decent which immediately follows the output computations and which also includes the local feedback and the crosstalk. Subsequent to the gradient propagation, the weights can be normalized, thereby preventing convergence to a local optimum. Education of the network can be incremental both on and off-line. An educated network is suitable for modeling and controlling dynamic nonlinear systems and time series systems and predicting the outputs as well as hidden states and parameters. The educated network can also be further educated during on-line processing.
NASA Astrophysics Data System (ADS)
Xie, Yiwei; Zhuang, Leimeng; Boller, Klaus-Jochen; Lowery, Arthur James
2017-06-01
Optical delay lines implemented in photonic integrated circuits (PICs) are essential for creating robust and low-cost optical signal processors on miniaturized chips. In particular, tunable delay lines enable a key feature of programmability for the on-chip processing functions. However, the previously investigated tunable delay lines are plagued by a severe drawback of delay-dependent loss due to the propagation loss in the constituent waveguides. In principle, a serial-connected amplifier can be used to compensate such losses or perform additional amplitude manipulation. However, this solution is generally unpractical as it introduces additional burden on chip area and power consumption, particularly for large-scale integrated PICs. Here, we report an integrated tunable delay line that overcomes the delay-dependent loss, and simultaneously allows for independent manipulation of group delay and amplitude responses. It uses a ring resonator with a tunable coupler and a semiconductor optical amplifier in the feedback path. A proof-of-concept device with a free spectral range of 11.5 GHz and a delay bandwidth in the order of 200 MHz is discussed in the context of microwave photonics and is experimentally demonstrated to be able to provide a lossless delay up to 1.1 to a 5 ns Gaussian pulse. The proposed device can be designed for different frequency scales with potential for applications across many other areas such as telecommunications, LIDAR, and spectroscopy, serving as a novel building block for creating chip-scale programmable optical signal processors.
Optical design of optical synthetic aperture telescope
NASA Astrophysics Data System (ADS)
Zhou, Chenghao; Wang, Zhile
2018-03-01
Optical synthetic aperture (OSA) is a promising solution for very high-resolution imaging while reducing its volume and mass. In this paper, first, the configuration of OSA systems are analyzed and the design methods of two types (Fizeau and Michelson) of OSA systems are summarized and researched. Second, Fizeau and Michelson OSA prototype systems are designed in detail. In the Michelson configuration, the instrument is made of sub-telescopes distributed in entrance pupil and combined by a common telescope via phase delay line. The design of Michelson configuration is more difficult than that of Fizeau configuration. In the design of Fizeau configuration, according to the third aberration theory tworeflective system is designed. Then the primary mirror of the two mirror system is replaced by the synthetic aperture. The whole system was simulated by Zemax software to obtain the Modulation transform function (MTF). In the design of Michelson configuration, the system is first divided into three parts: the afocal interferometric telescopes, beam combiner system and phase delay line. The three parts are designed respectively and then combined in Zemax software to obtain the MTF.
TECHNICAL DESIGN NOTE: Picosecond resolution programmable delay line
NASA Astrophysics Data System (ADS)
Suchenek, Mariusz
2009-11-01
The note presents implementation of a programmable delay line for digital signals. The tested circuit has a subnanosecond delay range programmable with a resolution of picoseconds. Implementation of the circuit was based on low-cost components, easily available on the market.
Wang, Yuan-Jay
2010-10-01
This paper develops a systematic and straightforward methodology to characterize and quench the friction-induced limit cycle conditions in electro-hydraulic servovalve control systems with transport delay in the transmission line. The nonlinear friction characteristic is linearized by using its corresponding describing function. The delay time in the transmission line, which could accelerate the generation of limit cycles is particularly considered. The stability equation method together with parameter plane method provides a useful tool for the establishment of necessary conditions to sustain a limit cycle directly in the constructed controller coefficient plane. Also, the stable region, the unstable region, and the limit cycle region are identified in the parameter plane. The parameter plane characterizes a clear relationship between limit cycle amplitude, frequency, transport delay, and the controller coefficients to be designed. The stability of the predicted limit cycle is checked by plotting stability curves. The stability of the system is examined when the viscous gain changes with respect to the temperature of the working fluid. A feasible stable region is characterized in the parameter plane to allow a flexible choice of controller gains. The robust prevention of limit cycle is achieved by selecting controller gains from the asymptotic stability region. The predicted results are verified by simulations. It is seen that the friction-induced limit cycles can be effectively predicted, removed, and quenched via the design of the compensator even in the case of viscous gain and delay time variations unconditionally. Copyright © 2010 ISA. Published by Elsevier Ltd. All rights reserved.
VLTI-PRIMA fringe tracking testbed
NASA Astrophysics Data System (ADS)
Abuter, Roberto; Rabien, Sebastian; Eisenhauer, Frank; Sahlmann, Johannes; Di Lieto, Nicola; Haug, Marcus; Wallander, Anders; Lévêque, Samuel; Ménardi, Serge; Delplancke, Françoise; Schuhler, Nicolas; Kellner, Stefan; Frahm, Robert
2006-06-01
One of the key components of the planned VLTI dual feed facility PRIMA is the Fringe Sensor Unit (FSU). Its basic function is the instantaneous measurement of the Optical Path Difference (OPD) between two beams. The FSU acts as the sensor for a complex control system involving optical delay lines and laser metrology with the aim of removing any OPD introduced by the atmosphere and the beam relay. We have initiated a cooperation between ESO and MPE with the purpose of systematically testing this Fringe Tracking Control System in a laboratory environment. This testbed facility is being built at MPE laboratories with the aim to simulate the VLTI and includes FSUs, OPD controller, metrology and in-house built delay lines. In this article we describe this testbed in detail, including the environmental conditions in the laboratory, and present the results of the testbed subsystem characterisation.
Dong, Xiangshu; Kim, Wan Kyu; Lim, Yong-Pyo; Kim, Yeon-Ki; Hur, Yoonkang
2013-02-01
We investigated the mechanism regulating cytoplasmic male sterility (CMS) in Brassica rapa ssp. pekinensis using floral bud transcriptome analyses of Ogura-CMS Chinese cabbage and its maintainer line in B. rapa 300-K oligomeric probe (Br300K) microarrays. Ogura-CMS Chinese cabbage produced few and infertile pollen grains on indehiscent anthers. Compared to the maintainer line, CMS plants had shorter filaments and plant growth, and delayed flowering and pollen development. In microarray analysis, 4646 genes showed different expression, depending on floral bud size, between Ogura-CMS and its maintainer line. We found 108 and 62 genes specifically expressed in Ogura-CMS and its maintainer line, respectively. Ogura-CMS line-specific genes included stress-related, redox-related, and B. rapa novel genes. In the maintainer line, genes related to pollen coat and germination were specifically expressed in floral buds longer than 3mm, suggesting insufficient expression of these genes in Ogura-CMS is directly related to dysfunctional pollen. In addition, many nuclear genes associated with auxin response, ATP synthesis, pollen development and stress response had delayed expression in Ogura-CMS plants compared to the maintainer line, which is consistent with the delay in growth and development of Ogura-CMS plants. Delayed expression may reduce pollen grain production and/or cause sterility, implying that mitochondrial, retrograde signaling delays nuclear gene expression. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.
The design of a breadboard cryogenic optical delay line for DARWIN
NASA Astrophysics Data System (ADS)
van den Dool, Teun C.; Kamphues, Fred; Fouss, B.; Henrioulle, K.; Kooijman, P. P.; Visser, Martijn; Velsink, G.; Fleury, K.
2004-09-01
TNO TPD, in cooperation with Micromega-Dynamics, SRON, Dutch Space and CSL, has designed a compact breadboard cryogenic delay line for use in future space interferometry missions. The work is performed under ESA contract in preparation for the DARWIN mission. The breadboard (BB) delay line is representative of a flight mechanism, with all materials and processes used being flight representative. The delay line has a single stage voice coil actuator for Optical Path Difference (OPD) control, driving a two-mirror cat's eye. Magnetic bearings provide frictionless and wear free operation with zero-hysteresis. Overall power consumption is below the ESA specification of 2.5 W. The power dissipated on the optical bench at 40 K is considerably less than the maximum allowable 25 mW. The design of the BB delay line has been completed. Verification testing, including functional testing at 40 K, is planned to start in the 4th quarter of 2004. The current design could also be adapted to the needs of the TPF-I mission.
The design of a breadboard cryogenic optical delay line for DARWIN
NASA Astrophysics Data System (ADS)
van den Dool, Teun; Kamphues, Fred; Fouss, B.; Henrioulle, K.; Kooijman, P. P.; Visser, Martijn; Velsink, G.; Fleury, K.
2004-09-01
TNO TPD, in cooperation with Micromega-Dynamics, SRON, Dutch Space and CSL, has designed a compact breadboard cryogenic delay line for use in future space interferometry missions. The work is performed under ESA contract in preparation for the DARWIN mission. The breadboard (BB) delay line is representative of a future flight mechanism, with all materials and processes used being flight representative. The delay line has a single stage voice coil actuator for Optical Path Difference (OPD) control, driving a two-mirror cat"s eye. Magnetic bearings provide frictionless and wear free operation with zero-hysteresis. Overall power consumption is below the ESA specification of 2.5 W. The power dissipated on the optical bench at 40 K is considerably less than the maximum allowable 25 mW. The BB delay line will be built in the second half of 2004. The manufacturing and assembly phase is followed by a comprehensive test program, including functional testing at 40 K in 2005. The tests will be carried out by Alcatel Space and SAGEIS-CSO.
Quantification of calcium using localized normalization on laser-induced breakdown spectroscopy data
NASA Astrophysics Data System (ADS)
Sabri, Nursalwanie Mohd; Haider, Zuhaib; Tufail, Kashif; Aziz, Safwan; Ali, Jalil; Wahab, Zaidan Abdul; Abbas, Zulkifly
2017-03-01
This paper focuses on localized normalization for improved calibration curves in laser-induced breakdown spectroscopy (LIBS) measurements. The calibration curves have been obtained using five samples consisting of different concentrations of calcium (Ca) in potassium bromide (KBr) matrix. The work has utilized Q-switched Nd:YAG laser installed in LIBS2500plus system with fundamental wavelength and laser energy of 650 mJ. Optimization of gate delay can be obtained from signal-to-background ratio (SBR) of Ca II 315.9 and 317.9 nm. The optimum conditions are determined in which having high spectral intensity and SBR. The highest spectral lines of ionic and emission lines of Ca at gate delay of 0.83 µs. From SBR, the optimized gate delay is at 5.42 µs for both Ca II spectral lines. Calibration curves consist of three parts; original intensity from LIBS experimentation, normalization and localized normalization of the spectral line intensity. The R2 values of the calibration curves plotted using locally normalized intensities of Ca I 610.3, 612.2 and 616.2 nm spectral lines are 0.96329, 0.97042, and 0.96131, respectively. The enhancement from calibration curves using the regression coefficient allows more accurate analysis in LIBS. At the request of all authors of the paper, and with the agreement of the Proceedings Editor, an updated version of this article was published on 24 May 2017.
Choi, Young Min; Suh, Yeunsu; Shin, Sangsu; Lee, Kichoon
2014-01-01
This study was designed to extensively characterize the skeletal muscle development in the low weight (LW) quail selected from random bred control (RBC) Japanese quail in order to provide a new avian model of impaired and delayed growth in physically normal animals. The LW line had smaller embryo and body weights than the RBC line in all age groups (P<0.05). During 3 to 42 d post-hatch, the LW line exhibited approximately 60% smaller weight of pectoralis major muscle (PM), mainly resulting from lower fiber numbers compared to the RBC line (P<0.05). During early post-hatch period when myotubes are still actively forming, the LW line showed impaired PM growth with prolonged expression of Pax7 and lower expression levels of MyoD, Myf-5, and myogenin (P<0.05), likely leading to impairment of myogenic differentiation and consequently, reduced muscle fiber formation. Additionally, the LW line had delayed transition of neonatal to adult myosin heavy chain isoform, suggesting delayed muscle maturation. This is further supported by the finding that the LW line continued to grow unlike the RBC line; difference in the percentages of PMW to body weights between both quail lines diminished with increasing age from 42 to 75 d post-hatch. This delayed muscle growth in the LW line is accompanied by higher levels of myogenin expression at 42 d (P<0.05), higher percentage of centered nuclei at 42 d (P<0.01), and greater rate of increase in fiber size between 42 and 75 d post-hatch (P<0.001) compared to the RBC line. Analysis of physiological, morphological, and developmental parameters during muscle development of the LW quail line provided a well-characterized avian model for future identification of the responsible genes and for studying mechanisms of hypoplasia and delayed muscle growth.
The big brown bat's perceptual dimension of target range
NASA Astrophysics Data System (ADS)
Simmons, James A.
2005-09-01
Big brown bats determine the distance to targets from echo delay, but information actually is entered onto the bat's psychological delay scale from two sources. The first is the target-ranging system itself, from the time that elapses between single-spike neural responses evoked by the broadcast and similar responses evoked by echoes at different delays. These responses register the FM sweeps of broadcasts or echoes, and the associated system of neural delay lines and coincidence detectors cross correlates the spectrograms along the time axis. The second source is the echo spectrum, which relates to shape expressed as range profile. The target-ranging system extracts this by fanning out to encompass parallel representations of many possible notch frequencies and notch widths in echoes. Bats perceive delay separations of 5-30 μs and have a resolution limit of about 2 μs, but interference amplifies small delay separations by transposing them into large changes in notch frequency, so only perception of intervals smaller than 5 μs is surprising. Experiments with phase-shifted echoes show that the psychological time scale can represent two different delays originating entirely in the time domain when they are at least as close together as 10 μs. [Work supported by NIH and ONR.
Surface acoustic wave unidirectional transducers for quantum applications
NASA Astrophysics Data System (ADS)
Ekström, Maria K.; Aref, Thomas; Runeson, Johan; Björck, Johan; Boström, Isac; Delsing, Per
2017-02-01
The conversion efficiency of electric microwave signals into surface acoustic waves in different types of superconducting transducers is studied with the aim of quantum applications. We compare delay lines containing either conventional symmetric transducers (IDTs) or unidirectional transducers (UDTs) at 2.3 GHz and 10 mK. The UDT delay lines improve the insertion loss with 4.7 dB and a directivity of 22 dB is found for each UDT, indicating that 99.4% of the acoustic power goes in the desired direction. The power lost in the undesired direction accounts for more than 90% of the total loss in IDT delay lines, but only ˜3% of the total loss in the floating electrode unidirectional transducer delay lines.
Dynamic sample size detection in learning command line sequence for continuous authentication.
Traore, Issa; Woungang, Isaac; Nakkabi, Youssef; Obaidat, Mohammad S; Ahmed, Ahmed Awad E; Khalilian, Bijan
2012-10-01
Continuous authentication (CA) consists of authenticating the user repetitively throughout a session with the goal of detecting and protecting against session hijacking attacks. While the accuracy of the detector is central to the success of CA, the detection delay or length of an individual authentication period is important as well since it is a measure of the window of vulnerability of the system. However, high accuracy and small detection delay are conflicting requirements that need to be balanced for optimum detection. In this paper, we propose the use of sequential sampling technique to achieve optimum detection by trading off adequately between detection delay and accuracy in the CA process. We illustrate our approach through CA based on user command line sequence and naïve Bayes classification scheme. Experimental evaluation using the Greenberg data set yields encouraging results consisting of a false acceptance rate (FAR) of 11.78% and a false rejection rate (FRR) of 1.33%, with an average command sequence length (i.e., detection delay) of 37 commands. When using the Schonlau (SEA) data set, we obtain FAR = 4.28% and FRR = 12%.
1980-12-01
distributions of Figs. 3 and 4 may be fitted quit, accurately by broken straight lines. If we had plotted the differential distributions directly...collection process. These fluctuations are smoothed by replacing the actual differential distribution by the derivative of the fitted broken-line lognormal...for each interval T. The constants in the distribution for each broken section of the lognormal approximations are found by fitting lines to the curve
Mixed Modeling of a SAW Delay Line Using VHDL-AMS
NASA Technical Reports Server (NTRS)
Wilson, William C.; Atkinson, Gary M.
2006-01-01
To aid in the development of SAW sensors for aerospace applications we have created a model of a SAW Delay line using VHDL. The model implements the Impulse Response method to calculate the frequency response, impedance, and insertion loss. The model includes optimization for the number of finger pairs in the IDTs and for the aperture height. This paper presents the model and the results from the model for a SAW delay line design.
Multiwire proportional chamber development
NASA Technical Reports Server (NTRS)
Doolittle, R. F.; Pollvogt, U.; Eskovitz, A. J.
1973-01-01
The development of large area multiwire proportional chambers, to be used as high resolution spatial detectors in cosmic ray experiments is described. A readout system was developed which uses a directly coupled, lumped element delay-line whose characteristics are independent of the MWPC design. A complete analysis of the delay-line and the readout electronic system shows that a spatial resolution of about 0.1 mm can be reached with the MWPC operating in the strictly proportional region. This was confirmed by measurements with a small MWPC and Fe-55 X-rays. A simplified analysis was carried out to estimate the theoretical limit of spatial resolution due to delta-rays, spread of the discharge along the anode wire, and inclined trajectories. To calculate the gas gain of MWPC's of different geometrical configurations a method was developed which is based on the knowledge of the first Townsend coefficient of the chamber gas.
Optical resonators for true-time-delay beam steering
NASA Astrophysics Data System (ADS)
Gesell, Leslie H.; Evanko, Stephen M.
1996-06-01
Conventional true time delay beamforming and steering devices rely on switching between various lengths of delay line. Therefore only discrete delays are possible. Proposed is a new photonics concept for true time delay beamforming which provides a finely controlled continuum of delays with switching speeds on the order of 10's of nanoseconds or faster. The architecture uses an array of waveguide cavities with different resonate frequencies to channelize the signal. Each spectral component of the signal is phase shifted by an amount proportional to the frequency of that component and the desired time delay. These phase shifted spectral components are then summed to obtain the delayed signal. This paper provides an overview of the results of a Phase I SBIR contract where this concept has been refined and analyzed. The parameters for an operational system are determined and indication of the feasibility of this approach is given. Among the issues addressed are the requirements of the resonators and the methods necessary to implement fiber optic Bragg gratings as these resonators.
NASA Astrophysics Data System (ADS)
Siegmund, O.; Vallerga, J.; Welsh, B.; Rabin, M.; Bloch, J.
In recent years EAG has implemented a variety of high-resolution, large format, photon-counting MCP detectors in space instrumentation for satellite FUSE, GALEX, IMAGE, SOHO, HST-COS, rocket, and shuttle payloads. Our scheme of choice has been delay line readouts encoding photon event position centroids, by determination of the difference in arrival time of the event charge at the two ends of a distributed resistive-capacitive (RC) delay line. Our most commonly used delay line configuration is the cross delay line (XDL). In its simplest form the delay-line encoding electronics consists of a fast amplifier for each end of the delay line, followed by time-to-digital converters (TDC's). We have achieved resolutions of < 25 μm in tests over 65 mm x 65 mm (3k x3k resolution elements) with excellent linearity. Using high speed TDC's, we have been able to encode event positions for random photon rates of ~1 MHz, while time tagging events using the MCP output signal to better than 100 ps. The unique ability to record photon X,Y,T high fidelity information has advantages over "frame driven" recording devices for some important applications. For example we have built open face and sealed tube cross delay line detectors used for biological fluorescence lifetime imaging, observation of flare stars, orbital satellites and space debris with the GALEX satellite, and time resolved imaging of the Crab Pulsar with a telescope as small as 1m. Although microchannel plate delay line detectors meet many of the imaging and timing demands of various applications, they have limitations. The relatively high gain (107) reduces lifetime and local counting rate, and the fixed delay (10's of ns) makes multiple simultaneous event recording problematic. To overcome these limitations we have begun development of cross strip readout anodes for microchannel plate detectors. The cross strip (XS) anode is a coarse (~0.5 mm) multi-layer metal and ceramic pattern of crossed fingers on an alumina substrate. The charge cloud is matched to the anode period so that it is collected on several neighboring fingers to ensure an accurate event charge centroid can be determined. Each finger of the anode is connected to a low noise charge sensitive amplifier and followed by subsequent A/D conversion of individual strip charge values and a hardware centroid determination of better than 1/100 of a strip are possible. Recently we have commissioned a full 32 x 32 mm XS open face laboratory detector and demonstrated excellent resolution (<6 μm FWHM, ~5k x 5k resolution) using low MCP gain (<5 x 105) thus increasing the MCP local counting rate capacity and overall lifetime of the detector system. In collaboration with Los Alamos National Laboratory, NASA and NSF we are developing high rate (>107 Hz) XS encoding electronics that will encode temporally simultaneous events (non spatially overlapping). Sealed tube XS detectors with GaAs and other photocathodes are also under development to increase detection efficiency and extend the sensitivity range. This type of sensor could be a significant enabling technology for several important applications, including airborne and space situational awareness, high-speed adaptive optics (by increasing the SNR and speed in the control loop), astronomy of transient and time-variable sources, optical metrology, and secure quantum communication (as a receiver of cryptographic keys for three-dimensional imaging), single-molecule fluorescence lifetime microscopy (simultaneously tracking and measuring ~1000 molecules), optical/NIR LIDAR, hybrid mass spectrometry and optical night-time/reconnaissance (LANL-ASPIRE).
Integrable microwave filter based on a photonic crystal delay line.
Sancho, Juan; Bourderionnet, Jerome; Lloret, Juan; Combrié, Sylvain; Gasulla, Ivana; Xavier, Stephane; Sales, Salvador; Colman, Pierre; Lehoucq, Gaelle; Dolfi, Daniel; Capmany, José; De Rossi, Alfredo
2012-01-01
The availability of a tunable delay line with a chip-size footprint is a crucial step towards the full implementation of integrated microwave photonic signal processors. Achieving a large and tunable group delay on a millimetre-sized chip is not trivial. Slow light concepts are an appropriate solution, if propagation losses are kept acceptable. Here we use a low-loss 1.5 mm-long photonic crystal waveguide to demonstrate both notch and band-pass microwave filters that can be tuned over the 0-50-GHz spectral band. The waveguide is capable of generating a controllable delay with limited signal attenuation (total insertion loss below 10 dB when the delay is below 70 ps) and degradation. Owing to the very small footprint of the delay line, a fully integrated device is feasible, also featuring more complex and elaborate filter functions.
On-line estimation and compensation of measurement delay in GPS/SINS integration
NASA Astrophysics Data System (ADS)
Yang, Tao; Wang, Wei
2008-10-01
The chief aim of this paper is to propose a simple on-line estimation and compensation method of GPS/SINS measurement delay. The causes of time delay for GPS/SINS integration are analyzed in this paper. New Kalman filter state equations augmented by measurement delay and modified measurement equations are derived. Based on an open-loop Kalman filter, several simulations are run, results of which show that by the proposed method, the estimation and compensation error of measurement delay is below 0.1s.
NASA Astrophysics Data System (ADS)
Cho, Young Y.; Chang, Cheng-Chung; Wang, Lihong V.; Zou, Jun
2015-03-01
To achieve real-time photoacoustic tomography (PAT), massive transducer arrays and data acquisition (DAQ) electronics are needed to receive the PA signals simultaneously, which results in complex and high-cost ultrasound receiver systems. To address this issue, we have developed a new PA data acquisition approach using acoustic time delay. Optical fibers were used as parallel acoustic delay lines (PADLs) to create different time delays in multiple channels of PA signals. This makes the PA signals reach a single-element transducer at different times. As a result, they can be properly received by single-channel DAQ electronics. However, due to their small diameter and fragility, using optical fiber as acoustic delay lines poses a number of challenges in the design, construction and packaging of the PADLs, thereby limiting their performances and use in real imaging applications. In this paper, we report the development of new silicon PADLs, which are directly made from silicon wafers using advanced micromachining technologies. The silicon PADLs have very low acoustic attenuation and distortion. A linear array of 16 silicon PADLs were assembled into a handheld package with one common input port and one common output port. To demonstrate its real-time PAT capability, the silicon PADL array (with its output port interfaced with a single-element transducer) was used to receive 16 channels of PA signals simultaneously from a tissue-mimicking optical phantom sample. The reconstructed PA image matches well with the imaging target. Therefore, the silicon PADL array can provide a 16× reduction in the ultrasound DAQ channels for real-time PAT.
Jing, Wencai; Zhang, Yimo; Zhou, Ge
2002-07-15
A new structure for bit synchronization in a tera-bit/s optical interconnection network has been designed using micro-electro-mechanical system (MEMS) technique. Link multiplexing has been adopted to reduce data packet communication latency. To eliminate link set-up time, adjustable optical delay lines (AODLs) have been adopted to shift the phases of the distributed optical clock signals for bit synchronization. By changing the optical path distance of the optical clock signal, the phase of the clock signal can be shifted at a very high resolution. A phase-shift resolution of 0.1 ps can be easily achieved with 30-microm alternation of the optical path length in vacuum.
Implementation of Nonlinear Control Laws for an Optical Delay Line
NASA Technical Reports Server (NTRS)
Hench, John J.; Lurie, Boris; Grogan, Robert; Johnson, Richard
2000-01-01
This paper discusses the implementation of a globally stable nonlinear controller algorithm for the Real-Time Interferometer Control System Testbed (RICST) brassboard optical delay line (ODL) developed for the Interferometry Technology Program at the Jet Propulsion Laboratory. The control methodology essentially employs loop shaping to implement linear control laws. while utilizing nonlinear elements as means of ameliorating the effects of actuator saturation in its coarse, main, and vernier stages. The linear controllers were implemented as high-order digital filters and were designed using Bode integral techniques to determine the loop shape. The nonlinear techniques encompass the areas of exact linearization, anti-windup control, nonlinear rate limiting and modal control. Details of the design procedure are given as well as data from the actual mechanism.
Method and system for selecting data sampling phase for self timed interface logic
Hoke, Joseph Michael; Ferraiolo, Frank D.; Lo, Tin-Chee; Yarolin, John Michael
2005-01-04
An exemplary embodiment of the present invention is a method for transmitting data among processors over a plurality of parallel data lines and a clock signal line. A receiver processor receives both data and a clock signal from a sender processor. At the receiver processor a bit of the data is phased aligned with the transmitted clock signal. The phase aligning includes selecting a data phase from a plurality of data phases in a delay chain and then adjusting the selected data phase to compensate for a round-off error. Additional embodiments include a system and storage medium for transmitting data among processors over a plurality of parallel data lines and a clock signal line.
Dejardin, Olivier; Droulon, Karine; Launoy, Guy; Defer, Gilles
2018-01-01
Objective In MS, Socio-Economic status (SES) may influence healthcare and access to disease-modifying treatments (DMTs). Optimising delays to switch patients to a second-line DMT may hamper disease progression most effectively and achieve long term disease control. The objective of this study is to identify the influence of SES on the delay between first and second line DMT in RRMS patients, in Western-Normandy, France. Methods The association between SES and the delay to access a second-line DMT were studied using data from the MS registry of Western-Normandy including 733 patients with a diagnosis of RRMS during the period in question [1982–2011]. We used the European Deprivation Index (EDI), a score with a rank level inversely related to SES. We performed multivariate adjusted Cox models for studying EDI effect on the delay between first and second line DMT. Results No significant influence of SES was observed on delay to access a second-line DMT if first-line DMT exposure time was less than 5 years. After 5 years from initiation of first-line treatment the risk of accessing a second-line DMT is 3 times higher for patients with lower deprivation indices (1st quintile of EDI) ([HR] 3.14 95%CI [1.72–5.72], p-value<0.001) compared to patients with higher values (EDI quintiles 2 to 5). Interpretation In RRMS, a high SES may facilitate access to a second-line DMT a few years after first-line DMT exposure. Greater consideration should also be given to the SES of MS patients as a risk factor in therapeutic healthcare issues throughout medical follow-up. PMID:29390025
Acousto-optic replication of ultrashort laser pulses
NASA Astrophysics Data System (ADS)
Yushkov, Konstantin B.; Molchanov, Vladimir Ya.; Ovchinnikov, Andrey V.; Chefonov, Oleg V.
2017-10-01
Precisely controlled sequences of ultrashort laser pulses are required in various scientific and engineering applications. We developed a phase-only acousto-optic pulse shaping method for replication of ultrashort laser pulses in a TW laser system. A sequence of several Fourier-transform-limited pulses is generated from a single femtosecond laser pulse by means of applying a piecewise linear phase modulation over the whole emission spectrum. Analysis demonstrates that the main factor which limits maximum delay between the pulse replicas is spectral resolution of the acousto-optic dispersive delay line used for pulse shaping. In experiments with a Cr:forsterite laser system, we obtained delays from 0.3 to 3.5 ps between two replicas of 190 fs transform-limited pulses at the central wavelength of laser emission, 1230 nm.
Line length dependencies in interconnect optimization
NASA Astrophysics Data System (ADS)
Kadoch, Daniel; Duane, Michael; Lee, Yohan
1997-09-01
Metal line delay has become increasingly important for ULSI devices. Numerous expressions and software tools have been developed to describe interconnect delay as a function of the geometry and layout. Although many of these formulas have line length effects, this has not been explored in depth. Most software tools are either geared towards circuit designers, or involve more complex and CPU-intensive 3D modeling. In this work, PISCES (a 2D device simulator) was used to extract metal capacitance per unit length. We extend this approach for various lengths by creating a ladder network of the RC components and simulating in SPICE, or using simple closed-form Elmore delay equations. A new key result is that there are optimum metal line width/space for a fixed pitch and height/space ratios that are metal length dependent. For metal lines shorter than about 1500 micrometers , it is better to have narrower metal lines, and for lengths less than 500 micrometers , shrinking metal height is desirable because the penalty in resistance is more than compensated by the decrease in capacitance. For longer lines, the time delay is dominated by resistance, and wider, taller lines are better. Increasing metal spacing or reducing dielectric constant were beneficial for both long and short metal lines.
The dynamics and control of large flexible space structures X, part 1
NASA Technical Reports Server (NTRS)
Bainum, Peter M.; Reddy, A. S. S. R.; Li, Feiyue; Diarra, Cheick M.
1987-01-01
The effect of delay in the control system input on the stability of a continuously acting controller which is designed without considering the delay is studied. The stability analysis of a second order plant is studied analytically and verified numerically. For this example it is found that the system becomes unstable for a delay which is equivalent to only 16 percent of its natural period of motion. It is also observed that even a small amount of natural damping in the system can increase the amount of delay that can be tolerated before the onset of instability. The delay problem is formulated in the discrete time domain and an analysis procedure suggested. The maximum principle from optimal control theory is applied to minimize the time required for the slewing of a general rigid spacecraft. The slewing motion need not be restricted to a single axis maneuver. The minimum slewing time is calculated based on a quasi-linearization algorithm for the resulting two point boundary value problem. Numerical examples based on the rigidized in-orbit model of the SCOLE also include the more general reflector line-of-sight slewing maneuvers.
NASA Astrophysics Data System (ADS)
van den Dool, T. C.; Kamphues, F.; Gielesen, W.; Dorrepaal, M.; Doelman, N.; Loix, N.; Verschueren, J. P.; Kooijman, P. P.; Visser, M.; Velsink, G.; Fleury, K.
2005-08-01
TNO, in cooperation with Micromega-Dynamics, SRON, Dutch Space and CSL, has developed a compact breadboard cryogenic Optical Delay Line for use in future space interferometry missions. The work is performed under ESA contract in preparation for the DARWIN mission. The breadboard delay line is representative of a future flight mechanism, with all used materials and processes being flight representative. The delay line has a single stage voice coil actuator for Optical Path Difference (OPD) control, driving a two-mirror cat's eye. Magnetic bearings are used for guiding. They provide frictionless and wear free operation with zero-hysteresis. The manufacturing, assembly and acceptance testing have been completed and are reported in this paper. The verification program, including functional testing at 40 K, will start in the final quarter of 2005.
Chan, V O; Moran, D E; Shine, S; Eustace, S J
2013-10-01
To assess the incidence and clinical significance of medial joint line bone bruising following acute ankle inversion injury. Forty-five patients who underwent ankle magnetic resonance imaging (MRI) within 2 weeks of acute ankle inversion injury were included in this prospective study. Integrity of the lateral collateral ligament complex, presence of medial joint line bone bruising, tibio-talar joint effusion, and soft-tissue swelling were documented. Clinical follow-up at 6 months was carried out to determine the impact of injury on length of time out of work, delay in return to normal walking, delay in return to sports activity, and persistence of medial joint line pain. Thirty-seven patients had tears of the anterior talofibular ligament (ATFL). Twenty-six patients had medial joint line bone bruising with altered marrow signal at the medial aspect of the talus and congruent surface of the medial malleolus. A complete ATFL tear was seen in 92% of the patients with medial joint line bone bruising (p = 0.05). Patients with an ATFL tear and medial joint line bone bruising had a longer delay in return to normal walking (p = 0.0002), longer delay in return to sports activity (p = 0.0001), and persistent medial joint line pain (p = 0.0003). There was no statistically significant difference in outcome for the eight patients without ATFL tears. Medial joint line bone bruising following an acute ankle inversion injury was significantly associated with a complete ATFL tear, longer delay in the return to normal walking and sports activity, as well as persistent medial joint line pain. Its presence should prompt detailed assessment of the lateral collateral ligament complex, particularly the ATFL. Copyright © 2013 The Royal College of Radiologists. Published by Elsevier Ltd. All rights reserved.
NASA Technical Reports Server (NTRS)
Kim, Sungwan
1994-01-01
System parameters should be tracked on-line to build a reconfigurable control system even though there exists an abrupt change. For this purpose, a new performance index that we are studying is the speed of adaptation- how quickly does the system determine that a change has occurred? In this paper, a new, robust algorithm that is optimized to minimize the time delay in detecting a change for fixed false alarm probability is proposed. Simulation results for the aircraft lateral motion with a known or unknown change in control gain matrices, in the presence of doublet input, indicate that the algorithm works fairly well. One of its distinguishing properties is that detection delay of this algorithm is superior to that of Whiteness Test.
Nonlinear femtosecond pump-probe spectroscopy using a power-encoded soliton delay line.
Saint-Jalm, Sarah; Andresen, Esben Ravn; Bendahmane, Abdelkrim; Kudlinski, Alexandre; Rigneault, Hervé
2016-01-01
We show femtosecond time-resolved nonlinear pump-probe spectroscopy using a fiber soliton as the probe pulse. Furthermore, we exploit soliton dynamics to record an entire transient trace with a power-encoded delay sweep. The power-encoded delay line takes advantage of the dependency of the soliton trajectory in the (λ,z) space upon input power; the difference in accumulated group delay between trajectories converts a fast power sweep into a fast delay sweep. We demonstrate the concept by performing transient absorption spectroscopy in a test sample and validate it against a conventional pump-probe setup.
1981-01-22
Arsenal Contract DUAA25-69-C- 0301 dated 3-10-69 for "Services to design and develop an automated line for assembly of Safety Adapter, Fuze, 1564...determine the line will function at the design rate of 5,000 acceptable assemblies per day and collect production data for incorporation into final...0,000 M564 Delay Arming Mechanisms of the line: Determine that the line will function at the design rate of 5,000. acceotabie asswml I es/day. Collect
Characteristics of an Optical Delay Line for Radar Testing
2016-04-12
MANUFACTURER PERFORMANCE MEASUREMENT ....................................... 2 3 NRL PERFORMANCE MEASUREMENT ...Third-Order-Intercept (TOI) ................... 7 3.4 Phase Noise Measurement ...MANUFACTURER PERFORMANCE MEASUREMENT Figures 3 to 5 are the Miteq’s FODL performance measured by the manufacturer prior to shipping the system to NRL
Line sensing device for ultrafast laser acoustic inspection using adaptive optics
Hale, Thomas C.; Moore, David S.
2003-11-04
Apparatus and method for inspecting thin film specimens along a line. A laser emits pulses of light that are split into first, second, third and fourth portions. A delay is introduced into the first portion of pulses and the first portion of pulses is directed onto a thin film specimen along a line. The third portion of pulses is directed onto the thin film specimen along the line. A delay is introduced into the fourth portion of pulses and the delayed fourth portion of pulses are directed to a photorefractive crystal. Pulses of light reflected from the thin film specimen are directed to the photorefractive crystal. Light from the photorefractive crystal is collected and transmitted to a linear photodiode array allowing inspection of the thin film specimens along a line.
Propagation of light through small clouds of cold interacting atoms
NASA Astrophysics Data System (ADS)
Jennewein, S.; Sortais, Y. R. P.; Greffet, J.-J.; Browaeys, A.
2016-11-01
We demonstrate experimentally that a dense cloud of cold atoms with a size comparable to the wavelength of light can induce large group delays on a laser pulse when the laser is tightly focused on it and is close to an atomic resonance. Delays as large as -10 ns are observed, corresponding to "superluminal" propagation with negative group velocities as low as -300 m /s . Strikingly, this large delay is associated with a moderate extinction owing to the very small size of the dense cloud. It implies that a large phase shift is imprinted on the continuous laser beam. Our system may thus be useful for applications to quantum technologies, such as variable delay line for individual photons or phase imprint between two beams at the single-photon level.
Electron-Beam Switches For A High Peak Power Sled-II Pulse Compressor
DOE Office of Scientific and Technical Information (OSTI.GOV)
Hirshfield, Jay, L.
2015-12-02
Omega-P demonstrated triggered electron-beam switches on the L=2 m dual-delay-line X-band pulse compressor at Naval Research Laboratory (NRL). In those experiments, with input pulses of up to 9 MW from the Omega-P/NRL X-band magnicon, output pulses having peak powers of 140-165 MW and durations of 16-20 ns were produced, with record peak power gains M of 18-20. Switch designs are described based on the successful results that should be suitable for use with the existing SLAC SLED-II delay line system, to demonstrate C=9, M=7, and n>>78%, yielding 173ns compressed pulses with peak powers up to 350MW with input of amore » single 50-MW.« less
The Palomar Testbed Interferometer
NASA Technical Reports Server (NTRS)
Colavita, M. M.; Wallace, J. K.; Hines, B. E.; Gursel, Y.; Malbet, F.; Palmer, D. L.; Pan, X. P.; Shao, M.; Yu, J. W.; Boden, A. F.
1999-01-01
The Palomar Testbed Interferometer (PTI) is a long-baseline infrared interferometer located at Palomar Observatory, California. It was built as a testbed for interferometric techniques applicable to the Keck Interferometer. First fringes were obtained in 1995 July. PTI implements a dual-star architecture, tracking two stars simultaneously for phase referencing and narrow-angle astrometry. The three fixed 40 cm apertures can be combined pairwise to provide baselines to 110 m. The interferometer actively tracks the white-light fringe using an array detector at 2.2 microns and active delay lines with a range of +/-38 m. Laser metrology of the delay lines allows for servo control, and laser metrology of the complete optical path enables narrow-angle astrometric measurements. The instrument is highly automated, using a multiprocessing computer system for instrument control and sequencing.
Effects of channel tap spacing on delay-lock tracking
NASA Astrophysics Data System (ADS)
Dana, Roger A.; Milner, Brian R.; Bogusch, Robert L.
1995-12-01
High fidelity simulations of communication links operating through frequency selective fading channels require both accurate channel models and faithful reproduction of the received signal. In modern radio receivers, processing beyond the analog-to-digital converter (A/D) is done digitally, so a high fidelity simulation is actually an emulation of this digital signal processing. The 'simulation' occurs in constructing the output of the A/D. One approach to constructing the A/D output is to convolve the channel impulse response function with the combined impulse response of the transmitted modulation and the A/D. For both link simulations and hardware channel simulators, the channel impulse response function is then generated with a finite number of samples per chip, and the convolution is implemented in a tapped delay line. In this paper we discuss the effects of the channel model tap spacing on the performance of delay locked loops (DLLs) in both direct sequence and frequency hopped spread spectrum systems. A frequency selective fading channel is considered, and the channel impulse response function is constructed with an integer number of taps per modulation symbol or chip. The tracking loop time delay is computed theoretically for this tapped delay line channel model and is compared to the results of high fidelity simulations of actual DLLs. A surprising result is obtained. The performance of the DLL depends strongly on the number of taps per chip. As this number increases the DLL delay approaches the theoretical limit.
Mina, Adel F; Warnecke, Nicholas L
2016-01-01
Background: Pulmonary Vein Antral isolation (PVAI) is currently the standard of care for both paroxysmal and persistent atrial fibrillation ablation. Reconnection to the pulmonary vein is the most common cause of recurrence of atrial fibrillation. Achieving the endpoint of bidirectional block (BDB) for cavotricuspid isthmus dependant flutter has improved our outcomes for atrial flutter ablation. With this we tried to achieve long delays in the pulmonary veins antral lines prior to complete isolation comparable to those delays found in patient with bidirectional block of atrial flutter lines. Study Objective: The objective of this paper was to evaluate feasibility and efficacy of achieving Bidirectional long delays in pulmonary vein antral lines prior to Bidirectional Block in patient with paroxysmal atrial fibrillation. Method: A retrospective analysis was performed on patients who had paroxysmal atrial fibrillation procedures at Unity Point Methodist from January 2015 to January 2016. 20 consecutive patients with paroxysmal atrial fibrillation who had AF ablation using the Bi-Bi technique were evaluated. Result: Mean age was 63, number of antiarrhythmic used prior to ablation was 1.4, mean left atrial size was 38 mm. Mean chads score was 1.3. Mean EF was 53%. Long delays in the left antral circumferential lines were achieved with mean delay of 142 milliseconds +/-100. Also long delays in the right antral circumferential lines were achieved with mean delay of 150 milliseconds +/-80. 95 % (19/20) of patients were free of any atrial arrhythmias and were off antiarrhythmic medications for AF post procedure. There was only one transient complication in one patient who developed a moderate pericardial effusion that was successfully drained with no hemodynamic changes. The only patient who had recurrence was found to have asymptomatic AF with burden on his device <1%, this patient was also found to have non PV triggers for his AF. In patients with only PV triggered AF success rate was 100%. Conclusion: Achievement of Bidirectional long delays in pulmonary vein antral lines prior to Bidirectional Block in patient with paroxysmal atrial fibrillation is feasible and highly effective technique in this small cohort of patients studied. We also outlined the procedure in details.
Three degree-of-freedom force feedback control for robotic mating of umbilical lines
NASA Technical Reports Server (NTRS)
Fullmer, R. Rees
1988-01-01
The use of robotic manipulators for the mating and demating of umbilical fuel lines to the Space Shuttle Vehicle prior to launch is investigated. Force feedback control is necessary to minimize the contact forces which develop during mating. The objective is to develop and demonstrate a working robotic force control system. Initial experimental force control tests with an ASEA IRB-90 industrial robot using the system's Adaptive Control capabilities indicated that control stability would by a primary problem. An investigation of the ASEA system showed a 0.280 second software delay between force input commands and the output of command voltages to the servo system. This computational delay was identified as the primary cause of the instability. Tests on a second path into the ASEA's control computer using the MicroVax II supervisory computer show that time delay would be comparable, offering no stability improvement. An alternative approach was developed where the digital control system of the robot was disconnected and an analog electronic force controller was used to control the robot's servosystem directly, allowing the robot to use force feedback control while in rigid contact with a moving three-degree-of-freedom target. An alternative approach was developed where the digital control system of the robot was disconnected and an analog electronic force controller was used to control the robot's servo system directly. This method allowed the robot to use force feedback control while in rigid contact with moving three degree-of-freedom target. Tests on this approach indicated adequate force feedback control even under worst case conditions. A strategy to digitally-controlled vision system was developed. This requires switching between the digital controller when using vision control and the analog controller when using force control, depending on whether or not the mating plates are in contact.
Quantifying the line-of-sight mass distributions for time-delay lenses with stellar masses
NASA Astrophysics Data System (ADS)
Rusu, Cristian; Fassnacht, Chris; Treu, Tommaso; Suyu, Sherry; Auger, Matt; Koopmans, Leon; Marshall, Phil; Wong, Kenneth; Collett, Thomas; Agnello, Adriano; Blandford, Roger; Courbin, Frederic; Hilbert, Stefan; Meylan, Georges; Sluse, Dominique
2014-12-01
Measuring cosmological parameters with a realistic account of systematic uncertainties is currently one of the principal challenges of physical cosmology. Building on our recent successes with two gravitationally lensed systems, we have started a program to achieve accurate cosmographic measurements from five gravitationally lensed quasars. We aim at measuring H_0 with an accuracy better than 4%, comparable to but independent from measurements by current BAO, SN or Cepheid programs. The largest current contributor to the error budget in our sample is uncertainty about the line-of-sight mass distribution and environment of the lens systems. In this proposal, we request wide-field u-band imaging of the only lens in our sample without already available Spitzer/IRCA observations, B1608+656. The proposed observations are critical for reducing these uncertainties by providing accurate redshifts and in particular stellar masses for galaxies in the light cones of the target lens system. This will establish lensing as a powerful and independent tool for determining cosmography, in preparation for the hundreds of time-delay lenses that will be discovered by future surveys.
Pump-probe micro-spectroscopy by means of an ultra-fast acousto-optics delay line.
Audier, Xavier; Balla, Naveen; Rigneault, Hervé
2017-01-15
We demonstrate femtosecond pump-probe transient absorption spectroscopy using a programmable dispersive filter as an ultra-fast delay line. Combined with fast synchronous detection, this delay line allows for recording of 6 ps decay traces at 34 kHz. With such acquisition speed, we perform single point pump-probe spectroscopy on bulk samples in 80 μs and hyperspectral pump-probe imaging over a field of view of 100 μm in less than a second. The usability of the method is illustrated in a showcase experiment to image and discriminate between two pigments in a mixture.
NASA Astrophysics Data System (ADS)
Labutin, Timur A.; Popov, Andrey M.; Zaytsev, Sergey M.; Zorov, Nikita B.; Belkov, Mikhail V.; Kiris, Vasilii V.; Raikov, Sergey N.
2014-09-01
Accurate and reliable quantitative determination of non-metal corrosion agents in concrete is still an actual task of analytical use of LIBS. Two double-pulse LIBS systems were tested as a tool for the determination of chlorine, sulfur and carbon in concretes. Both systems had collinear configuration; a laboratory setup was equipped with an ICCD and two lasers (355/532 nm + 540 nm), but a CCD was a detector for a mobile system with one laser (1064 nm). Analytical lines of Cl I at 837.59 nm, S I at 921 nm and C I at 247.86 nm were used to plot calibration curves. Optimal interpulse delays for the laboratory setup were 4 μs for chlorine and 2.8 μs for carbon, while an interpulse delay of 2 μs was optimal for chlorine and sulfur determination with the mobile system. We suggested the normalization of the Cl I line at 837.59 nm to the Mg II line at 279.08 nm (visible at 837.23 nm in the third order) to compensate for pulse-to-pulse fluctuations of chlorine lines. It provided the decrease of the detection limit of chlorine from 400 ppm to 50 ppm. Therefore, we reported that LIBS can be used to determine main corrosive active substances under ambient conditions in concrete below critical threshold values. Moreover, the application of the mobile system for in-situ qualitative assessment of corrosion way of a steel cage of a swimming pool dome was also demonstrated. It was found that chloride corrosion due to the disinfection of water was the main way for corrosion of the open part steel and the steel rebar inside the concrete.
Lag and anticipating synchronization without time-delay coupling.
Corron, Ned J; Blakely, Jonathan N; Pethel, Shawn D
2005-06-01
We describe a new method for achieving approximate lag and anticipating synchronization in unidirectionally coupled chaotic oscillators. The method uses a specific parameter mismatch between the drive and response that is a first-order approximation to true time-delay coupling. As a result, an adjustable lag or anticipation effect can be achieved without the need for a variable delay line, making the method simpler and more economical to implement in many physical systems. We present a stability analysis, demonstrate the method numerically, and report experimental observation of the effect in radio-frequency electronic oscillators. In the circuit experiments, both lag and anticipation are controlled by tuning a single capacitor in the response oscillator.
Graphene-based fine-tunable optical delay line for optical beamforming in phased-array antennas.
Tatoli, Teresa; Conteduca, Donato; Dell'Olio, Francesco; Ciminelli, Caterina; Armenise, Mario N
2016-06-01
The design of an integrated graphene-based fine-tunable optical delay line on silicon nitride for optical beamforming in phased-array antennas is reported. A high value of the optical delay time (τg=920 ps) together with a compact footprint (4.15 mm2) and optical loss <27 dB make this device particularly suitable for highly efficient steering in active phased-array antennas. The delay line includes two graphene-based Mach-Zehnder interferometer switches and two vertically stacked microring resonators between which a graphene capacitor is placed. The tuning range is obtained by varying the value of the voltage applied to the graphene electrodes, which controls the optical path of the light propagation and therefore the delay time. The graphene provides a faster reconfigurable time and low values of energy dissipation. Such significant advantages, together with a negligible beam-squint effect, allow us to overcome the limitations of conventional RF beamformers. A highly efficient fine-tunable optical delay line for the beamsteering of 20 radiating elements up to ±20° in the azimuth direction of a tile in a phased-array antenna of an X-band synthetic aperture radar has been designed.
A Low Power Linear Phase Programmable Long Delay Circuit.
Rodriguez-Villegas, Esther; Logesparan, Lojini; Casson, Alexander J
2014-06-01
A novel linear phase programmable delay is being proposed and implemented in a 0.35 μm CMOS process. The delay line consists of N cascaded cells, each of which delays the input signal by Td/N, where Td is the total line delay. The delay generated by each cell is programmable by changing a clock frequency and is also fully independent of the frequency of the input signal. The total delay hence depends only on the chosen clock frequency and the total number of cascaded cells. The minimum clock frequency is limited by the maximum time a voltage signal can effectively be held by an individual cell. The maximum number of cascaded cells will be limited by the effects of accumulated offset due to transistor mismatch, which eventually will affect the operating mode of the individual transistors in a cell. This latter limitation has however been dealt with in the topology by having an offset compensation mechanism that makes possible having a large number of cascaded cells and hence a long resulting delay. The delay line has been designed for scalp-based neural activity analysis that is predominantly in the sub-100 Hz frequency range. For these signals, the delay generated by a 31-cell cascade has been demonstrated to be programmable from 30 ms to 3 s. Measurement results demonstrate a 31 stage, 50 Hz bandwidth, 0.3 s delay that operates from a 1.1 V supply with power consumption of 270 nW.
Performance of a hard X-ray split-and-delay optical system with a wavefront division
Hirano, Takashi; Osaka, Taito; Morioka, Yuki; ...
2018-01-01
The performance of a hard X-ray split-and-delay optical (SDO) system with a wavefront division scheme was investigated at the hard X-ray free-electron laser facility SACLA. For the wavefront division, beam splitters made of edge-polished perfect Si(220) crystals were employed. We characterized the beam properties of the SDO system, and investigated its capabilities for beam manipulation and diagnostics. First, it was confirmed that shot-to-shot non-invasive diagnostics of pulse energies for both branches in the SDO system was feasible. Second, nearly ideal and identical focal profiles for both branches were obtained with a spot size of ~1.5 µm in full width atmore » half-maximum. Third, a spatial overlap of the two focused beams with a sub-µm accuracy was achieved by fine tuning of the SDO system. Finally, a reliable tunability of the delay time between two pulses was confirmed. The time interval was measured with an X-ray streak camera by changing the path length of the variable-delay branch. As a result, errors from the fitted line were evaluated to be as small as ±0.4 ps over a time range of 60 ps.« less
Performance of a hard X-ray split-and-delay optical system with a wavefront division
DOE Office of Scientific and Technical Information (OSTI.GOV)
Hirano, Takashi; Osaka, Taito; Morioka, Yuki
The performance of a hard X-ray split-and-delay optical (SDO) system with a wavefront division scheme was investigated at the hard X-ray free-electron laser facility SACLA. For the wavefront division, beam splitters made of edge-polished perfect Si(220) crystals were employed. We characterized the beam properties of the SDO system, and investigated its capabilities for beam manipulation and diagnostics. First, it was confirmed that shot-to-shot non-invasive diagnostics of pulse energies for both branches in the SDO system was feasible. Second, nearly ideal and identical focal profiles for both branches were obtained with a spot size of ~1.5 µm in full width atmore » half-maximum. Third, a spatial overlap of the two focused beams with a sub-µm accuracy was achieved by fine tuning of the SDO system. Finally, a reliable tunability of the delay time between two pulses was confirmed. The time interval was measured with an X-ray streak camera by changing the path length of the variable-delay branch. As a result, errors from the fitted line were evaluated to be as small as ±0.4 ps over a time range of 60 ps.« less
NASA Astrophysics Data System (ADS)
Oh, Haekwan; Fu, Chen; Yang, Sang Sik; Wang, Wen; Lee, Keekeun
2012-04-01
A surface acoustic wave (SAW)-based gyroscope with an 80 MHz central frequency was fabricated on a 128° YX LiNbO3 piezoelectric substrate. The fabricated gyroscope is composed of a SAW resonator, metallic dots and a SAW reflective delay line. The SAW resonator, which is activated by a voltage-controlled oscillator, generates a stable standing wave with a large amplitude at an 80 MHz resonant frequency, and the metallic dots induce a Coriolis force and generate a secondary SAW in the direction orthogonal to the propagating standing wave. The SAW reflective delay line is employed to measure the Coriolis effect by analyzing the deviations in the resonant frequency of the SAW reflective delay line. A combined finite element method/boundary element method was utilized to extract the optimal device parameters prior to fabrication. The device was fabricated according to the modeling results and then measured on a rate table. When the device was subjected to an angular rotation, a secondary SAW from the vibrating metallic dots was generated owing to the Coriolis force, resulting in a perturbation of the propagating SAW in the SAW reflective delay line. Depending on the angular velocity, the reflection peak of SAW reflective delay line was changed linearly, and this change was measured by the network analyzer. The measured results matched the modeling results well. The obtained sensitivity was approximately 1.23 deg/(deg/s) in an angular rate range of 0-2000 deg s-1. Good thermal and shock stabilities were observed during the evaluation process proving the shock and heat robustness of the fabricated SAW gyroscope.
Real-time energy-saving metro train rescheduling with primary delay identification
Li, Keping; Schonfeld, Paul
2018-01-01
This paper aims to reschedule online metro trains in delay scenarios. A graph representation and a mixed integer programming model are proposed to formulate the optimization problem. The solution approach is a two-stage optimization method. In the first stage, based on a proposed train state graph and system analysis, the primary and flow-on delays are specifically analyzed and identified with a critical path algorithm. For the second stage a hybrid genetic algorithm is designed to optimize the schedule, with the delay identification results as input. Then, based on the infrastructure data of Beijing Subway Line 4 of China, case studies are presented to demonstrate the effectiveness and efficiency of the solution approach. The results show that the algorithm can quickly and accurately identify primary delays among different types of delays. The economic cost of energy consumption and total delay is considerably reduced (by more than 10% in each case). The computation time of the Hybrid-GA is low enough for rescheduling online. Sensitivity analyses further demonstrate that the proposed approach can be used as a decision-making support tool for operators. PMID:29474471
Pagès, Pierre-Benoit; Facy, Olivier; Mordant, Pierre; Ladoire, Sylvain; Magnin, Guy; Lokiec, Francois; Ghiringhelli, Francois; Bernard, Alain
2013-01-01
Background The lung is a frequent site of colorectal cancer (CRC) metastases. After surgical resection, lung metastases recurrences have been related to the presence of micrometastases, potentially accessible to a high dose chemotherapy administered via adjuvant isolated lung perfusion (ILP). We sought to determine in vitro the most efficient drug when administered to CRC cell lines during a short exposure and in vivo its immediate and delayed tolerance when administered via ILP. Methods First, efficacy of various cytotoxic molecules against a panel of human CRC cell lines was tested in vitro using cytotoxic assay after a 30-minute exposure. Then, early (operative) and delayed (1 month) tolerance of two concentrations of the molecule administered via ILP was tested on 19 adult pigs using hemodynamic, biological and histological criteria. Results In vitro, gemcitabine (GEM) was the most efficient drug against selected CRC cell lines. In vivo, GEM was administered via ILP at regular (20 µg/ml) or high (100 µg/ml) concentrations. GEM administration was associated with transient and dose-dependant pulmonary vasoconstriction, leading to a voluntary decrease in pump inflow in order to maintain a stable pulmonary artery pressure. After this modulation, ILP using GEM was not associated with any systemic leak, systemic damage, and acute or delayed histological pulmonary toxicity. Pharmacokinetics studies revealed dose-dependant uptake associated with heterogenous distribution of the molecule into the lung parenchyma, and persistent cytotoxicity of venous effluent. Conclusions GEM is effective against CRC cells even after a short exposure. ILP with GEM is a safe and reproducible technique. PMID:23527205
Surface elastic wave detectors
NASA Technical Reports Server (NTRS)
Lawson, R. L.
1971-01-01
The potential applications of acoustic surface wave technology to multiplex communication systems such as data-bus, are examined. The goals are primarily to characterize certain aspects of surface wave trapped delay lines, surface wave modulation techniques, and surface wave applications that are relevant to the evaluation of surface wave devices in multiplex systems. The results indicate that there is a potential for the application of surface wave technology in data-bus type systems.
Constraints on frequency-dependent violations of Shapiro delay from GW150914
NASA Astrophysics Data System (ADS)
Kahya, Emre O.; Desai, Shantanu
2016-05-01
On 14th September 2015, a transient gravitational wave (GW150914) was detected by the two LIGO detectors at Hanford and Livingston from the coalescence of a binary black hole system located at a distance of about 400 Mpc. We point out that GW150914 experienced a Shapiro delay due to the gravitational potential of the mass distribution along the line of sight of about 1800 days. Also, the near-simultaneous arrival of gravitons over a frequency range of about 200 Hz within a 0.2 s window allows us to constrain any violations of Shapiro delay and Einstein's equivalence principle between the gravitons at different frequencies. From the calculated Shapiro delay and the observed duration of the signal, frequency-dependent violations of the equivalence principle for gravitons are constrained to an accuracy of O (10-9).
ELECTRONIC PHASE CONTROL CIRCUIT
Salisbury, J.D.; Klein, W.W.; Hansen, C.F.
1959-04-21
An electronic circuit is described for controlling the phase of radio frequency energy applied to a multicavity linear accelerator. In one application of the circuit two cavities are excited from a single radio frequency source, with one cavity directly coupled to the source and the other cavity coupled through a delay line of special construction. A phase detector provides a bipolar d-c output signal proportional to the difference in phase between the voltage in the two cavities. This d-c signal controls a bias supply which provides a d-c output for varying the capacitnce of voltage sensitive capacitors in the delay line. The over-all operation of the circuit is completely electronic, overcoming the time response limitations of the electromechanical control systems, and the relative phase relationship of the radio frequency voltages in the two caviiies is continuously controlled to effect particle acceleration.
Noise and time delay induce critical point in a bistable system
NASA Astrophysics Data System (ADS)
Zhang, Jianqiang; Nie, Linru; Yu, Lilong; Zhang, Xinyu
2014-07-01
We study relaxation time Tc of time-delayed bistable system driven by two cross-correlated Gaussian white noises that one is multiplicative and the other is additive. By means of numerical calculations, the results indicate that: (i) Combination of noise and time delay can induce two critical points about the relaxation time at some certain noise cross-correlation strength λ under the condition that the multiplicative intensity D equals to the additive noise intensity α. (ii) For each fixed D or α, there are two symmetrical critical points which locates in the regions of positive and negative correlations, respectively. Namely, as λ equals to the critical value λc, Tc is independent of the delay time and the result of Tc versus τ is a horizontal line, but as |λ|>|λc| (or |λ|<|λc|), the relaxation time Tc monotonically increases (or decreases) with the delay time increasing. (iii) In the presence of D = α, the change of λc with D is two symmetrical curves about the axis of λc = 0, and the critical value λc is close to zero for a smaller D, which approaches to +1 or -1 for a greater D.
Automation of the longwall mining system
NASA Technical Reports Server (NTRS)
Zimmerman, W.; Aster, R. W.; Harris, J.; High, J.
1982-01-01
Cost effective, safe, and technologically sound applications of automation technology to underground coal mining were identified. The longwall analysis commenced with a general search for government and industry experience of mining automation technology. A brief industry survey was conducted to identify longwall operational, safety, and design problems. The prime automation candidates resulting from the industry experience and survey were: (1) the shearer operation, (2) shield and conveyor pan line advance, (3) a management information system to allow improved mine logistics support, and (4) component fault isolation and diagnostics to reduce untimely maintenance delays. A system network analysis indicated that a 40% improvement in productivity was feasible if system delays associated with all of the above four areas were removed. A technology assessment and conceptual system design of each of the four automation candidate areas showed that state of the art digital computer, servomechanism, and actuator technologies could be applied to automate the longwall system.
VERNIER CHRONOTRON UTILIZING AT LEAST TWO SHORTED DELAY LINES
Rufer, R.P.
1964-02-25
An improved vernier chronotron featuring pulse-forming circuits of a ringing'' or back and forth'' oscillatory type is described. A delay line shorted at both ends together with transistor circuitry to introduce a pulse into that line and also to provide reinforcement of the pulse as it oscillates between the pulse-reflective extremities is provided. A transistorized coincidence circuit is also provided. Enhanced measurement of time intervals in the nanosecond range is afforded. (AEC)
Neutron-flux profile monitor for use in a fission reactor
Kopp, M.K.; Valentine, K.H.
1981-09-15
A neutron flux monitor is provided which consists of a plurality of fission counters arranged as spaced-apart point detectors along a delay line. As a fission event occurs in any one of the counters, two delayed current pulses are generated at the output of the delay line. The time separation of the pulses identifies the counter in which the particular fission event occurred. Neutron flux profiles of reactor cores can be more accurately measured as a result.
Neutron flux profile monitor for use in a fission reactor
Kopp, Manfred K.; Valentine, Kenneth H.
1983-01-01
A neutron flux monitor is provided which consists of a plurality of fission counters arranged as spaced-apart point detectors along a delay line. As a fission event occurs in any one of the counters, two delayed current pulses are generated at the output of the delay line. The time separation of the pulses identifies the counter in which the particular fission event occured. Neutron flux profiles of reactor cores can be more accurately measured as a result.
The influence of micro-vibration on space-borne Fourier transform spectrometers
NASA Astrophysics Data System (ADS)
Bai, Shaojun; Hou, Lizhou; Ke, Junyu
2014-11-01
The space-borne Fourier Transform Spectrometers (FTS) are widely used for atmospheric studies and planetary explorations. An adapted version of the classical Michelson interferometer have succeeded in several space missions, which utilized a rotating arm carrying a pair of cube corner retro-reflectors to produce a variable optical path difference (OPD), and a metrology laser source to generate the trigger signals. One characteristic of this kind of FTS is that it is highly sensitive to micro-vibration disturbances. However, a variety of mechanical disturbances are present as the satellite is in orbit, such as flying wheels, pointing mechanisms and cryocoolers. Therefore, this paper investigates the influence of micro-vibration on the space-borne FTS. Firstly, the interferogram of metrology laser under harmonic disturbances is analyzed. The results show that the zero crossings of interferogram shift periodically, and it gives rise to ghost lines in the retrieved spectra. The amplitudes of ghost lines increase rapidly with the increasing of micro-vibration levels. As to the system that employs the constant OPD sampling strategy, the effect of zero-crossing shifting is reduced significantly. Nevertheless, the time delays between the reference signal and the main signal acquisition are inevitable because of the electronic circuit. Thus, the effect of time delays on the interferogram and eventually on the spectra is simulated. The analysis suggests that the amplitudes of ghost line in spectra increase with the increasing of time delay intervals.
Non-contact thickness measurement using UTG
NASA Technical Reports Server (NTRS)
Bui, Hoa T. (Inventor)
1996-01-01
A measurement structure for determining the thickness of a specimen without mechanical contact but instead employing ultrasonic waves including an ultrasonic transducer and an ultrasonic delay line connected to the transducer by a retainer or collar. The specimen, whose thickness is to be measured, is positioned below the delay line. On the upper surface of the specimen a medium such as a drop of water is disposed which functions to couple the ultrasonic waves from the delay line to the specimen. A receiver device, which may be an ultrasonic thickness gauge, receives reflected ultrasonic waves reflected from the upper and lower surface of the specimen and determines the thickness of the specimen based on the time spacing of the reflected waves.
Holistic Facial Composite Creation and Subsequent Video Line-up Eyewitness Identification Paradigm.
Davis, Josh P; Maigut, Andreea C; Jolliffe, Darrick; Gibson, Stuart J; Solomon, Chris J
2015-12-24
The paradigm detailed in this manuscript describes an applied experimental method based on real police investigations during which an eyewitness or victim to a crime may create from memory a holistic facial composite of the culprit with the assistance of a police operator. The aim is that the composite is recognized by someone who believes that they know the culprit. For this paradigm, participants view a culprit actor on video and following a delay, participant-witnesses construct a holistic system facial composite. Controls do not construct a composite. From a series of arrays of computer-generated, but realistic faces, the holistic system construction method primarily requires participant-witnesses to select the facial images most closely meeting their memory of the culprit. Variation between faces in successive arrays is reduced until ideally the final image possesses a close likeness to the culprit. Participant-witness directed tools can also alter facial features, configurations between features and holistic properties (e.g., age, distinctiveness, skin tone), all within a whole face context. The procedure is designed to closely match the holistic manner by which humans' process faces. On completion, based on their memory of the culprit, ratings of composite-culprit similarity are collected from the participant-witnesses. Similar ratings are collected from culprit-acquaintance assessors, as a marker of composite recognition likelihood. Following a further delay, all participants--including the controls--attempt to identify the culprit in either a culprit-present or culprit-absent video line-up, to replicate circumstances in which the police have located the correct culprit, or an innocent suspect. Data of control and participant-witness line-up outcomes are presented, demonstrating the positive influence of holistic composite construction on identification accuracy. Correlational analyses are conducted to measure the relationship between assessor and participant-witness composite-culprit similarity ratings, delay, identification accuracy, and confidence to examine which factors influence video line-up outcomes.
Holistic Facial Composite Creation and Subsequent Video Line-up Eyewitness Identification Paradigm
Davis, Josh P.; Maigut, Andreea C.; Jolliffe, Darrick; Gibson, Stuart J.; Solomon, Chris J.
2015-01-01
The paradigm detailed in this manuscript describes an applied experimental method based on real police investigations during which an eyewitness or victim to a crime may create from memory a holistic facial composite of the culprit with the assistance of a police operator. The aim is that the composite is recognized by someone who believes that they know the culprit. For this paradigm, participants view a culprit actor on video and following a delay, participant-witnesses construct a holistic system facial composite. Controls do not construct a composite. From a series of arrays of computer-generated, but realistic faces, the holistic system construction method primarily requires participant-witnesses to select the facial images most closely meeting their memory of the culprit. Variation between faces in successive arrays is reduced until ideally the final image possesses a close likeness to the culprit. Participant-witness directed tools can also alter facial features, configurations between features and holistic properties (e.g., age, distinctiveness, skin tone), all within a whole face context. The procedure is designed to closely match the holistic manner by which humans’ process faces. On completion, based on their memory of the culprit, ratings of composite-culprit similarity are collected from the participant-witnesses. Similar ratings are collected from culprit-acquaintance assessors, as a marker of composite recognition likelihood. Following a further delay, all participants — including the controls — attempt to identify the culprit in either a culprit-present or culprit-absent video line-up, to replicate circumstances in which the police have located the correct culprit, or an innocent suspect. Data of control and participant-witness line-up outcomes are presented, demonstrating the positive influence of holistic composite construction on identification accuracy. Correlational analyses are conducted to measure the relationship between assessor and participant-witness composite-culprit similarity ratings, delay, identification accuracy, and confidence to examine which factors influence video line-up outcomes. PMID:26779673
A high-resolution time-to-digital converter using a three-level resolution
NASA Astrophysics Data System (ADS)
Dehghani, Asma; Saneei, Mohsen; Mahani, Ali
2016-08-01
In this article, a three-level resolution Vernier delay line time-to-digital converter (TDC) was proposed. The proposed TDC core was based on the pseudo-differential digital architecture that made it insensitive to nMOS and pMOS transistor mismatches. It also employed a Vernier delay line (VDL) in conjunction with an asynchronous read-out circuitry. The time interval resolution was equal to the difference of delay between buffers of upper and lower chains. Then, via the extra chain included in the lower delay line, resolution was controlled and power consumption was reduced. This method led to high resolution and low power consumption. The measurement results of TDC showed a resolution of 4.5 ps, 12-bit output dynamic range, and integral nonlinearity of 1.5 least significant bits. This TDC achieved the consumption of 68.43 µW from 1.1-V supply.
Subwavelength grating enabled on-chip ultra-compact optical true time delay line
Wang, Junjia; Ashrafi, Reza; Adams, Rhys; Glesk, Ivan; Gasulla, Ivana; Capmany, José; Chen, Lawrence R.
2016-01-01
An optical true time delay line (OTTDL) is a basic photonic building block that enables many microwave photonic and optical processing operations. The conventional design for an integrated OTTDL that is based on spatial diversity uses a length-variable waveguide array to create the optical time delays, which can introduce complexities in the integrated circuit design. Here we report the first ever demonstration of an integrated index-variable OTTDL that exploits spatial diversity in an equal length waveguide array. The approach uses subwavelength grating waveguides in silicon-on-insulator (SOI), which enables the realization of OTTDLs having a simple geometry and that occupy a compact chip area. Moreover, compared to conventional wavelength-variable delay lines with a few THz operation bandwidth, our index-variable OTTDL has an extremely broad operation bandwidth practically exceeding several tens of THz, which supports operation for various input optical signals with broad ranges of central wavelength and bandwidth. PMID:27457024
Fast time-correlated multi-element photon detector and method
Hayden, Carl C.; Chandler, David W.; Luong, A. Khai
2007-12-18
Photons emitted from a sample responsive to being excited by laser pulses are directed through a prism onto a photomultiplier tube having several spaced-apart anodes. The prism alters the path of each photon as a function of its wavelength so that the wavelength determines the anode to which the photon is directed. Taps of first and second delay lines that are coupled to respective alternating anodes. When an anode receives the photon, it generates a pulse that propagates through the delay line in opposite directions from its associated tap. A timer determines first and second times from the laser pulse to the pulse reaching the first and second ends of the delay line. The difference between the first and second times corresponds to the wavelength of the emitted photon and the sum of the first and second times corresponds to the emission delay of the emitted photon.
Subwavelength grating enabled on-chip ultra-compact optical true time delay line.
Wang, Junjia; Ashrafi, Reza; Adams, Rhys; Glesk, Ivan; Gasulla, Ivana; Capmany, José; Chen, Lawrence R
2016-07-26
An optical true time delay line (OTTDL) is a basic photonic building block that enables many microwave photonic and optical processing operations. The conventional design for an integrated OTTDL that is based on spatial diversity uses a length-variable waveguide array to create the optical time delays, which can introduce complexities in the integrated circuit design. Here we report the first ever demonstration of an integrated index-variable OTTDL that exploits spatial diversity in an equal length waveguide array. The approach uses subwavelength grating waveguides in silicon-on-insulator (SOI), which enables the realization of OTTDLs having a simple geometry and that occupy a compact chip area. Moreover, compared to conventional wavelength-variable delay lines with a few THz operation bandwidth, our index-variable OTTDL has an extremely broad operation bandwidth practically exceeding several tens of THz, which supports operation for various input optical signals with broad ranges of central wavelength and bandwidth.
[Study on physical deviation factors on laser induced breakdown spectroscopy measurement].
Wan, Xiong; Wang, Peng; Wang, Qi; Zhang, Qing; Zhang, Zhi-Min; Zhang, Hua-Ming
2013-10-01
In order to eliminate the deviation between the measured LIBS spectral line and the standard LIBS spectral line, and improve the accuracy of elements measurement, a research of physical deviation factors in laser induced breakdown spectroscopy technology was proposed. Under the same experimental conditions, the relationship of ablated hole effect and spectral wavelength was tested, the Stark broadening data of Mg plasma laser induced breakdown spectroscopy with sampling time-delay from 1.00 to 3.00 micros was also studied, thus the physical deviation influences such as ablated hole effect and Stark broadening could be obtained while collecting the spectrum. The results and the method of the research and analysis can also be applied to other laser induced breakdown spectroscopy experiment system, which is of great significance to improve the accuracy of LIBS elements measuring and is also important to the research on the optimum sampling time-delay of LIBS.
Efficient laser noise reduction method via actively stabilized optical delay line.
Li, Dawei; Qian, Cheng; Li, Ye; Zhao, Jianye
2017-04-17
We report a fiber laser noise reduction method by locking it to an actively stabilized optical delay line, specifically a fiber-based Mach-Zehnder interferometer with a 10 km optical fiber spool. The fiber spool is used to achieve large arm imbalance. The heterodyne signal of the two arms converts the laser noise from the optical domain to several megahertz, and it is used in laser noise reduction by a phase-locked loop. An additional phase-locked loop is induced in the system to compensate the phase noise due to environmentally induced length fluctuations of the optical fiber spool. A major advantage of this structure is the efficient reduction of out-of-loop frequency noise, particularly at low Fourier frequency. The frequency noise reaches -30 dBc/Hz at 1 Hz, which is reduced by more than 90 dB compared with that of the laser in its free-running state.
Chaos and Robustness in a Single Family of Genetic Oscillatory Networks
Fu, Daniel; Tan, Patrick; Kuznetsov, Alexey; Molkov, Yaroslav I.
2014-01-01
Genetic oscillatory networks can be mathematically modeled with delay differential equations (DDEs). Interpreting genetic networks with DDEs gives a more intuitive understanding from a biological standpoint. However, it presents a problem mathematically, for DDEs are by construction infinitely-dimensional and thus cannot be analyzed using methods common for systems of ordinary differential equations (ODEs). In our study, we address this problem by developing a method for reducing infinitely-dimensional DDEs to two- and three-dimensional systems of ODEs. We find that the three-dimensional reductions provide qualitative improvements over the two-dimensional reductions. We find that the reducibility of a DDE corresponds to its robustness. For non-robust DDEs that exhibit high-dimensional dynamics, we calculate analytic dimension lines to predict the dependence of the DDEs’ correlation dimension on parameters. From these lines, we deduce that the correlation dimension of non-robust DDEs grows linearly with the delay. On the other hand, for robust DDEs, we find that the period of oscillation grows linearly with delay. We find that DDEs with exclusively negative feedback are robust, whereas DDEs with feedback that changes its sign are not robust. We find that non-saturable degradation damps oscillations and narrows the range of parameter values for which oscillations exist. Finally, we deduce that natural genetic oscillators with highly-regular periods likely have solely negative feedback. PMID:24667178
Control Software for a High-Performance Telerobot
NASA Technical Reports Server (NTRS)
Kline-Schoder, Robert J.; Finger, William
2005-01-01
A computer program for controlling a high-performance, force-reflecting telerobot has been developed. The goal in designing a telerobot-control system is to make the velocity of the slave match the master velocity, and the environmental force on the master match the force on the slave. Instability can arise from even small delays in propagation of signals between master and slave units. The present software, based on an impedance-shaping algorithm, ensures stability even in the presence of long delays. It implements a real-time algorithm that processes position and force measurements from the master and slave and represents the master/slave communication link as a transmission line. The algorithm also uses the history of the control force and the slave motion to estimate the impedance of the environment. The estimate of the impedance of the environment is used to shape the controlled slave impedance to match the transmission-line impedance. The estimate of the environmental impedance is used to match the master and transmission-line impedances and to estimate the slave/environment force in order to present that force immediately to the operator via the master unit.
Observational selection biases in time-delay strong lensing and their impact on cosmography
NASA Astrophysics Data System (ADS)
Collett, Thomas E.; Cunnington, Steven D.
2016-11-01
Inferring cosmological parameters from time-delay strong lenses requires a significant investment of telescope time; it is therefore tempting to focus on the systems with the brightest sources, the highest image multiplicities and the widest image separations. We investigate if this selection bias can influence the properties of the lenses studied and the cosmological parameters inferred. Using an ellipsoidal power-law deflector population, we build a sample of double- and quadruple-image systems. Assuming reasonable thresholds on image separation and flux, based on current lens monitoring campaigns, we find that the typical density profile slopes of monitorable lenses are significantly shallower than the input ensemble. From a sample of quads, we find that this selection function can introduce a 3.5 per cent bias on the inferred time-delay distances if the properties of the input ensemble are (incorrectly) used as priors on the lens model. This bias remains at the 2.4 per cent level when high-resolution imaging of the quasar host is used to precisely infer the properties of individual lenses. We also investigate if the lines of sight for monitorable strong lenses are biased. The expectation value for the line-of-sight convergence is increased by 0.009 (0.004) for quads (doubles) implying a 0.9 per cent (0.4 per cent) bias on H0. We therefore conclude that whilst the properties of typical quasar lenses and their lines of sight do deviate from the global population, the total magnitude of this effect is likely to be a subdominant effect for current analyses, but has the potential to be a major systematic for samples of ˜25 or more lenses.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Greene, Zach S.; Suyu, Sherry H.; Treu, Tommaso
2013-05-01
In order to use strong gravitational lens time delays to measure precise and accurate cosmological parameters the effects of mass along the line of sight must be taken into account. We present a method to achieve this by constraining the probability distribution function of the effective line-of-sight convergence {kappa}{sub ext}. The method is based on matching the observed overdensity in the weighted number of galaxies to that found in mock catalogs with {kappa}{sub ext} obtained by ray-tracing through structure formation simulations. We explore weighting schemes based on projected distance, mass, luminosity, and redshift. This additional information reduces the uncertainty ofmore » {kappa}{sub ext} from {sigma}{sub {kappa}} {approx} 0.06 to {approx}0.04 for very overdense LOSs like that of the system B1608+656. For more common LOSs, {sigma}{sub {kappa}} is reduced to {approx}<0.03, corresponding to an uncertainty of {approx}< 3% on distance. This uncertainty has comparable effects on cosmological parameters to that arising from the mass model of the deflector and its immediate environment. Photometric redshifts based on g, r, i and K photometries are sufficient to constrain {kappa}{sub ext} almost as well as with spectroscopic redshifts. As an illustration, we apply our method to the system B1608+656. Our most reliable {kappa}{sub ext} estimator gives {sigma}{sub {kappa}} = 0.047 down from 0.065 using only galaxy counts. Although deeper multiband observations of the field of B1608+656 are necessary to obtain a more precise estimate, we conclude that griK photometry, in addition to spectroscopy to characterize the immediate environment, is an effective way to increase the precision of time-delay cosmography.« less
Delay Line Detectors for the UVCS and Sumer Instruments on the SOHO Satellite
NASA Technical Reports Server (NTRS)
Seigmund, O. H. W.; Stock, J. M.; Marsh, D. R.; Gummin, M. A.; Raffanti, R.; Hull, J.; Gaines, G. A.; Welsh, B.; Donakowski, B.; Jelinsky, P.;
1994-01-01
Microchannel plate based detectors with cross delay line image readout have been rapidly implemented for the SUMER and UVCS instruments aboard the Solar Orbiting Heliospheric Observatory (SOHO) mission to be launched in July 1995. In October 1993 a fast track program to build and characterize detectors and detector control electronics was initiated. We present the detector system design for the SOHO UVCS and SUMER detector programs, and results from the detector test program. Two deliverable detectors have been built at this point, a demonstration model for UVCS, and the flight Ly alpha detector for UVCS, both of which are to be delivered in the next few weeks. Test results have also been obtained with one other demonstration detector system. The detector format is 26mm x 9mm, with 1024 x 360 digitized pixels, using a low resistance Z stack of microchannel plates (MCP's) and a multilayer cross delay line anode (XDL). This configuration provides gains of approximately 2 x 10(exp 7) with good pulse height distributions (less than 50% FWHM) under uniform flood illumination, and background levels typical for this configuration (approximately 0.6 event cm (exp -2)sec(exp -1)). Local counting rates up to about 400 events/pixel/sec have been achieved with no degradation of the MCP gain. The detector and event encoding electronics achieves about 25 millimeter FVHM with good linearity (plus or minus approximately 1 pixel) and is stable to high global counting rates (greater than 4 x 10(exp 5) events sec(exp -1)). Flat field images are dominated by MCP fixed pattern noise and are stable, but the MCP multifiber modulation usually expected is uncharacteristically absent. The detector and electronics have also successfully passed both thermal vacuum and vibration tests.
76 FR 1559 - Guidelines for the Use of Electronic Voting Systems in Union Officer Elections
Federal Register 2010, 2011, 2012, 2013, 2014
2011-01-11
... voting. Id. However, there are still concerns regarding on-line computer security, viruses and attacks... casting votes at polling sites; electronic voting from remote site personal computers via the Internet..., Washington, DC 20210. Because of security precautions, the Department continues to experience delays in U.S...
DuPage, Michel; Cheung, Ann; Mazumdar, Claire; Winslow, Monte M.; Bronson, Roderick; Schmidt, Leah M.; Crowley, Denise; Chen, Jianzhu; Jacks, Tyler
2010-01-01
SUMMARY Neoantigens derived from somatic mutations in tumors may provide a critical link between the adaptive immune system and cancer. Here we describe a system to introduce exogenous antigens into genetically engineered mouse lung cancers to mimic tumor neoantigens. We show that endogenous T cells respond to and infiltrate tumors, significantly delaying malignant progression. Despite continued antigen expression, T cell infiltration does not persist and tumors ultimately escape immune attack. Transplantation of cell lines derived from these lung tumors or prophylactic vaccination against the autochthonous tumors, however, results in rapid tumor eradication or selection of tumors that lose antigen expression. These results provide insight into the dynamic nature of the immune response to naturally arising tumors. PMID:21251614
Peebles, Emma; Subbe, Christian P; Hughes, Paul; Gemmell, Les
2012-06-01
Rapid Response Teams aim to accelerate recognition and treatment of acutely unwell patients. Delays in delivery might undermine efficiency of the intervention. Our understanding of the causes of these delays is, as yet, incomplete. To identify modifiable causes of delays in the treatment of critically ill patients outside intensive care with a focus on factors amenable to system design. Review of care records and direct observation with process mapping of care delivered to 17 acutely unwell patients attended by a Rapid Response Team in a District General Hospital in the United Kingdom. Delays were defined as processes with no added value for patient care. Essential diagnostic and therapeutic procedures accounted for only 31% of time of care processes. Causes for delays could be classified into themes as (1) delays in call-out of the Rapid Response Team, (2) problems with team cohesion including poor communication and team efficiency and (3) lack of resources including lack of first line antibiotics, essential equipment, experienced staff and critical care beds. We identified a number of potentially modifiable causes for delays in care of acutely ill patients. Improved process design could include automated call-outs, a dedicated kit for emergency treatment in relevant clinical areas, increased usage of standard operating procedures and staff training using crew resource management techniques. Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.
Power Inversion in a Tapped Delay-Line Array.
1975-03-01
and identify by block number) This report discusses recent studies on adaptive arrays for theNavy ITACS system. The report considers the power inversion...this report we discuss recent studies on adaptive arrays for the Navy ITACS system. The goal of this research is to develop an adaptive antenna system...here is a continuation of earlier research on power inversion by Compton, Lee, and Schwegman [1,2,3,4]. This work differs from previous studies in that
NASA Astrophysics Data System (ADS)
Ahn, Sungsook; Lee, Sang Joon
2015-11-01
Wrinkle formation on the skin is an unwelcome guest to everybody. But if we truly understand how wrinkles can contribute to important biological functions, then we readily admit the wrinkles positively. In this study, we show how the wrinkles are advantageous and useful in many systems. In a plant system for example, by forming line patterned wrinkles the hydrogels covering on the seed surface contribute to delay the dehydration against varying water supply environments. Inspired by this plant hydrogel, it is experimentally and theoretically investigated how lined wrinkles are useful to conserve water inside while protect the individual from drying-out. This study would contribute to a variety of humidity-sensitive system development including artificial skin, humidity-actuated sensors and the like.
NASA Astrophysics Data System (ADS)
Li, Guang-Hui; Wang, An-Bang; Feng, Ye; Wang, Yang
2010-07-01
This paper numerically demonstrates synchronization and bidirectional communication without delay line by using two semiconductor lasers with strong mutual injection in a face-to-face configuration. These results show that both of the two lasers' outputs synchronize with their input chaotic carriers. In addition, simulations demonstrate that this kind of synchronization can be used to realize bidirectional communications without delay line. Further studies indicate that within a small deviation in message amplitudes of two sides (±6%), the message can be extracted with signal-noise-ratio more than 10 dB; and the signal-noise-ratio is extremely sensitive to the message rates mismatch of two sides, which may be used as a key of bidirectional communication.
Large-format high resolution microchannel plate detectors for ultraviolet astronomy
NASA Technical Reports Server (NTRS)
Martin, Christopher
1995-01-01
This report includes work on two types of two-dimensional position-sensitive detectors that were developed in this lab under this award. We worked to develop and optimize the wire-wound helical delay line detector (HDL) in the first and second years. Some early work on the HDL is contained in a paper included as Appendix A. In the second and third years we developed the concept for, then successfully designed and tested, both a lab prototype, and a flight prototype of the first, crossed delay line detector based on two orthogonal serpentine delay lines (SDL). Some of the work on the SDL is contained in a paper included as Appendix B. Appendix C contains copies of the invention report and record.
NASA Astrophysics Data System (ADS)
Erskine, David J.; Linder, E.; Wishnow, E.; Edelstein, J.; Sirk, M.; Muirhead, P.; Lloyd, J.; Kim, A.
2016-08-01
We describe demonstrations of remarkable robustness to instrumental noises by using a multiple delay externally dispersed interferometer (EDI) on stellar observations at the Hale telescope. Previous observatory EDI demonstrations used a single delay. The EDI (also called "TEDI") boosted the 2,700 resolution of the native TripleSpec NIR spectrograph (950-2450 nm) by as much as 10x to 27,000, using 7 overlapping delays up to 3 cm. We observed superb rejection of fixed pattern noises due to bad pixels, since the fringing signal responds only to changes in multiple exposures synchronous to the applied delay dithering. Remarkably, we observed a 20x reduction of reaction in the output spectrum to PSF shifts of the native spectrograph along the dispersion direction, using our standard processing. This allowed high resolution observations under conditions of severe and irregular PSF drift otherwise not possible without the interferometer. Furthermore, we recently discovered an improved method of weighting and mixing data between pairs of delays that can theoretically further reduce the net reaction to PSF drift to zero. We demonstrate a 350x reduction in reaction to a native PSF shift using a simple simulation. This technique could similarly reduce radial velocity noise for future EDI's that use two delays overlapped in delay space (or a single delay overlapping the native peak). Finally, we show an extremely high dynamic range EDI measurement of our ThAr lamp compared to a literature ThAr spectrum, observing weak features ( 0.001x height of nearest strong line) that occur between the major lines. Because of individuality of each reference lamp, accurate knowledge of its spectrum between the (unfortunately) sparse major lines is important for precision radial velocimetry.
An analog integrated circuit beamformer for high-frequency medical ultrasound imaging.
Gurun, Gokce; Zahorian, Jaime S; Sisman, Alper; Karaman, Mustafa; Hasler, Paul E; Degertekin, F Levent
2012-10-01
We designed and fabricated a dynamic receive beamformer integrated circuit (IC) in 0.35-μm CMOS technology. This beamformer IC is suitable for integration with an annular array transducer for high-frequency (30-50 MHz) intravascular ultrasound (IVUS) imaging. The beamformer IC consists of receive preamplifiers, an analog dynamic delay-and-sum beamformer, and buffers for 8 receive channels. To form an analog dynamic delay line we designed an analog delay cell based on the current-mode first-order all-pass filter topology, as the basic building block. To increase the bandwidth of the delay cell, we explored an enhancement technique on the current mirrors. This technique improved the overall bandwidth of the delay line by a factor of 6. Each delay cell consumes 2.1-mW of power and is capable of generating a tunable time delay between 1.75 ns to 2.5 ns. We successfully integrated the fabricated beamformer IC with an 8-element annular array. Experimental test results demonstrated the desired buffering, preamplification and delaying capabilities of the beamformer.
Analysis and experiments for delay compensation in attitude control of flexible spacecraft
NASA Astrophysics Data System (ADS)
Sabatini, Marco; Palmerini, Giovanni B.; Leonangeli, Nazareno; Gasbarri, Paolo
2014-11-01
Space vehicles are often characterized by highly flexible appendages, with low natural frequencies which can generate coupling phenomena during orbital maneuvering. The stability and delay margins of the controlled system are deeply affected by the presence of bodies with different elastic properties, assembled to form a complex multibody system. As a consequence, unstable behavior can arise. In this paper the problem is first faced from a numerical point of view, developing accurate multibody mathematical models, as well as relevant navigation and control algorithms. One of the main causes of instability is identified with the unavoidable presence of time delays in the GNC loop. A strategy to compensate for these delays is elaborated and tested using the simulation tool, and finally validated by means of a free floating platform, replicating the flexible spacecraft attitude dynamics (single axis rotation). The platform is equipped with thrusters commanded according to the on-off modulation of the Linear Quadratic Regulator (LQR) control law. The LQR is based on the estimate of the full state vector, i.e. including both rigid - attitude - and elastic variables, that is possible thanks to the on line measurement of the flexible displacements, realized by processing the images acquired by a dedicated camera. The accurate mathematical model of the system and the rigid and elastic measurements enable a prediction of the state, so that the control is evaluated taking the predicted state relevant to a delayed time into account. Both the simulations and the experimental campaign demonstrate that by compensating in this way the time delay, the instability is eliminated, and the maneuver is performed accurately.
The influence of ground conductivity on the structure of RF radiation from return strokes
NASA Technical Reports Server (NTRS)
Levine, D. M.; Gesell, L.
1984-01-01
The combination of the finite conductivity of the Earth plus the propagation of the return stroke current up the channel which results in an apparent time delay between the fast field changes and RF radiation for distant observers is shown. The time delay predicted from model return strokes is on the order of 20 micro and the received signal has the characteristics of the data observed in Virginia and Florida. A piecewise linear model for the return stroke channel and a transmission line model for current propagation on each segment was used. Radiation from each segment is calculated over a flat Earth with finite conductivity using asymptotics approximations for the Sommerfeld integrals. The radiation at the observer is processed by a model AM radio receiver. The output voltage was calculated for several frequencies between HF-UHF assuming a system bandwidth (300 kHz) characteristic of the system used to collect data in Florida and Virginia. Comparison with the theoretical fast field changes indicates a time delay of 20 microns.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Gondal, M. A., E-mail: magondal@kfupm.edu.sa; Baig, Umair; Dastageer, M. A.
A detection system based on laser induced breakdown spectroscopy (LIBS) was built using 266 nm wavelength pulsed laser from the fourth harmonic of Nd:YAG laser, 500 mm spectrograph and gated ICCD camera with built-in delay generator. The LIBS system was used to study the elemental composition in coffee available in the local market of Saudi Arabia for the detection of elements in coffee samples. The LIBS spectrum of coffee sample revealed the presence magnesium, calcium, aluminum, copper, sodium, barium, bromine, cobalt, chromium, cerium manganese and molybdenum. Atomic transition line of sodium is used to study the parametric dependence of LIBSmore » signal. The study of the dependence of LIBS signal on the laser pulse energy is proven to be linear and the dependence of LIBS signal on the time delay between the excitation and data acquisition showed a typical increase, a peak value and a decrease with the optimum excitation – acquisition delay at 400 ns.« less
Current status of the IOTA interferometer
NASA Astrophysics Data System (ADS)
Carleton, Nathaniel P.; Traub, Wesley A.; Lacasse, Marc G.; Nisenson, Peter; Pearlman, Michael R.; Reasenberg, Robert D.; Xu, Xinqi; Coldwell, Charles M.; Panasyuk, Alexander; Benson, James A.; Papaliolios, Costas; Predmore, Read; Schloerb, F. P.; Dyck, H. M.; Gibson, David M.
1994-06-01
The first two telescopes of the Infrared-Optical Telescope Array (IOTA) project are now in place and yielding data at the Smithsonian Institution's F. L. Whipple Observatory on Mt. Hopkins, near Tucson, Arizona. The IOTA collectors are 45 cm in diameter, and may be moved to various stations in an L-shaped configuration with a maximum baseline of 38 m. A third collector will be added as soon as funding permits. Each light-collector assembly consists of a siderostat feeding a stationary afocal Cassegrain telescope that produces a 10-X reduced parallel beam, which is in turn directed vertically downward by a piezo-driven active mirror that stabilizes the ultimate image position. The reduced beams enter an evacuated envelope and proceed to the corner of the array, where they are turned back along one arm for path compensation. The delay line, in one beam, consists of two parts: one dihedral reflector positioned in a slew-and-clamp mode to give the major part of the desired delay; and a second dihedral mounted on an air-bearing carriage to provide the variable delay that is needed. After delay, the beams exit from the vacuum and are directed by dichroic mirrors into the infrared beam-combination and detection system. The visible light passes on to another area, to the image-tracker detectors and the visible-light combination and detection system. The beams are combined in pupil-plane mode on beam splitters. The combined IR beams are conveyed to two cooled single-element InSb detectors. The combined visible-light beams are focussed by lenslet arrays onto multimode optical fibers that lead to the slit of a specially-designed prism spectrometer. For the visible mode, the delay line is run at several wavelengths on one side of the zero- path point, so that several cycles of interference occur across the spectrum. First results were obtained with the IR system, giving visibilities for several K and M stars, using 2.2 micrometers radiation on a N-S baseline of 21.2 m. From these measurements we obtained preliminary estimates of effective stellar diameters in the K band.
NASA Astrophysics Data System (ADS)
Saber, I.; Bartnik, A.; Wachulak, P.; Skrzeczanowski, W.; Jarocki, R.; Fiedorowicz, H.
2017-06-01
Spectral investigations of low-temperature photoionized plasmas created in a Kr/Ne/H2 gas mixture were performed. The low-temperature plasmas were generated by gas mixture irradiation using extreme ultraviolet pulses from a laser-plasma source. Emission spectra in the ultraviolet/visible range from the photoionized plasmas contained lines that mainly corresponded to neutral atoms and singly charged ions. Temporal variations in the plasma electron temperature and electron density were studied using different characteristic emission lines at various delay times. Results, based on Kr II lines, showed that the electron temperature decreased from 1.7 to 0.9 eV. The electron densities were estimated using different spectral lines at each delay time. In general, except for the Hβ line, in which the electron density decreased from 3.78 × 1016 cm-3 at 200 ns to 5.77 × 1015 cm-3 at 2000 ns, most of the electron density values measured from the different lines were of the order of 1015 cm-3 and decreased slightly while maintaining the same order when the delay time increased. The time dependences of the measured and simulated intensities of a spectral line of interest were also investigated. The validity of the partial or full local thermodynamic equilibrium (LTE) conditions in plasma was explained based on time-resolved electron density measurements. The partial LTE condition was satisfied for delay times in the 200 ns to 1500 ns range. The results are summarized, and the dominant basic atomic processes in the gas mixture photoionized plasma are discussed.
Diederich, Emily; Thomas, Laura; Mahnken, Jonathan; Lineberry, Matthew
2018-06-01
Within simulation-based mastery learning (SBML) courses, there is inconsistent inclusion of learner pretesting, which requires considerable resources and is contrary to popular instructional frameworks. However, it may have several benefits, including its direct benefit as a form of deliberate practice and its facilitation of more learner-specific subsequent deliberate practice. We consider an unexplored potential benefit of pretesting: its ability to predict variable long-term learner performance. Twenty-seven residents completed an SBML course in central line insertion. Residents were tested on simulated central line insertion precourse, immediately postcourse, and after between 64 and 82 weeks. We analyzed pretest scores' prediction of delayed test scores, above and beyond prediction by program year, line insertion experiences in the interim, and immediate posttest scores. Pretest scores related strongly to delayed test scores (r = 0.59, P = 0.01; disattenuated ρ = 0.75). The number of independent central lines inserted also related to year-delayed test scores (r = 0.44, P = 0.02); other predictors did not discernibly relate. In a regression model jointly predicting delayed test scores, pretest was a significant predictor (β = 0.487, P = 0.011); number of independent insertions was not (β = 0.234, P = 0.198). This study suggests that pretests can play a major role in predicting learner variance in learning gains from SBML courses, thus facilitating more targeted refresher training. It also exposes a risk in SBML courses that learners who meet immediate mastery standards may be incorrectly assumed to have equal long-term learning gains.
75 FR 75546 - Financial Management Service; Privacy Act of 1974, as Amended; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2010-12-03
.... Individuals receiving Federal payments electronically rarely have any delays or problems with their payments. In contrast, based on payment claims filed with FMS, nine out of ten problems with FMS-disbursed... mechanisms. Access to records is granted only as authorized by a business line manager at FMS or FMS's fiscal...
EIT in resonator chains: similarities and differences with atomic media
NASA Technical Reports Server (NTRS)
Matsko, A. B.; Maleki, L.; Savchenkov, A. A.; Ilchenko, V. S.
2004-01-01
We theoretically study a parallel configuration of two interacting whispering gallery mode optical resonators and show a narrow-band modal structure as a basis for a widely tunable delay line. For the optimum coupling configuration the system can possess an unusually narrow spectral feature with a much narrower bandwidth than the loaded bandwidth of each individual resonator.
Eric Kuehler; Jon Hathaway; Andrew Tirpak
2017-01-01
The use of green infrastructure for reducing stormwater runoff is increasingly common. One underâstudied component of the green infrastructure network is the urban forest system. Trees can play an important role as the âfirst line of defenseâ for restoring more natural hydrologic regimes in urban watersheds by intercepting rainfall, delaying runoff, infiltrating, and...
Federal Register 2010, 2011, 2012, 2013, 2014
2010-12-17
... Advisories may also be issued when lake ice exists that could be hazardous to small boats. Although river...-AA17 Limited Service Domestic Voyage Load Lines for River Barges on Lake Michigan, Delay of Effective... Lake Michigan. This rule finalized interim regulations that have been in effect since 2002, with some...
Atomic clouds as spectrally selective and tunable delay lines for single photons from quantum dots
NASA Astrophysics Data System (ADS)
Wildmann, Johannes S.; Trotta, Rinaldo; Martín-Sánchez, Javier; Zallo, Eugenio; O'Steen, Mark; Schmidt, Oliver G.; Rastelli, Armando
2015-12-01
We demonstrate a compact, spectrally selective, and tunable delay line for single photons emitted by quantum dots. This is achieved by fine-tuning the wavelength of the optical transitions of such "artificial atoms" into a spectral window in which a cloud of natural atoms behaves as a slow-light medium. By employing the ground-state fine-structure-split exciton confined in an InGaAs/GaAs quantum dot as a source of single photons at different frequencies and the hyperfine-structure-split D1 transition of Cs-vapors as a tunable delay medium, we achieve a differential delay of up 2.4 ns on a 7.5-cm-long path for photons that are only 60 μ eV (14.5 GHz) apart. To quantitatively explain the experimental data, we develop a theoretical model that accounts for both the inhomogeneous broadening of the quantum-dot emission lines and the Doppler broadening of the atomic lines. The concept we proposed here may be used to implement time-reordering operations aimed at erasing the "which-path" information that deteriorates entangled-photon emission from excitons with finite fine-structure splitting.
Effect of applied voltage and inter-pulse delay in spark-assisted LIBS
NASA Astrophysics Data System (ADS)
Robledo-Martinez, A.; Sobral, H.; Garcia-Villarreal, A.
2018-06-01
We report the results obtained in an investigation on the effect of the time delay between the laser and electrical pulses in a spark-assisted laser-induced breakdown spectroscopy (LIBS) experiment. The electrical discharge is produced by the discharge of a charged coaxial cable. This arrangement produces a fast unipolar current pulse (500 ns) that applies high power ( 600 kW) to the laser ablation plasma. The delay between the laser pulse and the electric pulse can be controlled at will in order to find the optimal time in terms of enhancement of the emitted lines. It was found that the application of the high voltage pulse enhances the ionic lines emitted by up to two orders of magnitude. An additional enhancement by a factor of 2-4 can be obtained delaying the application of the electric pulse by a time of 0.6-20 μs. In the tests it was noticed that the ionic lines were found to be clearly responsive to increments in the applied electric energy while the neutral lines did so marginally. Our results show that the intensification of the lines is mainly due to reheating of the ablation plasma as the application of the electrical pulse increments the temperature of the ablation plasma by about 50%. It is demonstrated that the present technique is an efficient way of intensifying the lines emitted without incurring in additional damage to the sample.
NASA Astrophysics Data System (ADS)
Cho, Y.; Chang, C.-C.; Wang, L. V.; Zou, J.
2016-02-01
This paper reports the development of a new 16-channel parallel acoustic delay line (PADL) array for real-time photoacoustic tomography (PAT). The PADLs were directly fabricated from single-crystalline silicon substrates using deep reactive ion etching. Compared with other acoustic delay lines (e.g., optical fibers), the micromachined silicon PADLs offer higher acoustic transmission efficiency, smaller form factor, easier assembly, and mass production capability. To demonstrate its real-time photoacoustic imaging capability, the silicon PADL array was interfaced with one single-element ultrasonic transducer followed by one channel of data acquisition electronics to receive 16 channels of photoacoustic signals simultaneously. A PAT image of an optically-absorbing target embedded in an optically-scattering phantom was reconstructed, which matched well with the actual size of the imaged target. Because the silicon PADL array allows a signal-to-channel reduction ratio of 16:1, it could significantly simplify the design and construction of ultrasonic receivers for real-time PAT.
Sun, Qiang; Yin, Jia; Yin, Xiao; Zou, Guanyang; Liang, Mingli; Zhong, Jieming; Walley, John; Wei, Xiaolin
2013-06-01
Moving the clinical services from tuberculosis (TB) dispensary to the integrated county hospital (called integrated approach) has been practiced in China; however, it is unknown the quality of TB care in the integrated approach and in the dispensary approach. A total of 202 new TB patients were investigated using structured questionnaires in three counties implementing the integrated approach and one county implementing the dispensary approach. The quality of TB care is measured based on success rate of treatment, medical expenditure, health system delay and second-line drug use. The integrated approach showed a high success treatment rate. The medical expenditure in the integrated approach was USD 432, significantly lower than that in the dispensary approach (Z = -5.771, P < 0.001). The integrated approach had a shorter health system delay (5 days) than the dispensary approach (32 days). Twenty-six percent of patients in integrated hospitals were prescribed with second-line TB drugs, significantly lower than that in the TB dispensary (47%, χ(2) = 7.452, P = 0.006). However, the medical expenditure, use of second-line anti-TB drug and liver-protection drugs indeed varied greatly across the three integrated hospitals. The integrated approach showed better quality of TB care, but the performance of the integrated hospitals varied greatly. A method to standardize TB treatment and management of this approach is urgent.
Kawamura, Kazuya; Kobayashi, Yo; Fujie, Masakatsu G
2010-01-01
Tele-surgery enables medical care even in remote regions, and has been accomplished in clinical cases by means of dedicated communication lines. To make tele-surgery a more widespread method of providing medical care, a surgical environment needs to be made available using public lines of communication, such as the Internet. Moreover, a support system during surgery is required, as the use of surgical tools is performed in an environment subject to delay. In our research, we focus on the operability of specific tasks conducted by surgeons during a medical procedure, with the aim of clarifying, by means of a simulation, the optimum environment for robotic tele-surgery. In the study, we set up experimental systems using our proposed simulation system. In addition, we investigate the mental workloads on subjects and verify the effect of visual-assistance information as a pilot study. The operability of the task of gripping soft tissue was evaluated using a subjective workload assessment tool, the NASA Task Load Index. Results show that the tasks were completed, but the workload did not improve to less than 300ms and 400ms in the simulated environment. Verifying the effect of the support system was an important task under a more-than 200ms delay using this experiment, and future studies will evaluate the operability of the system under varying conditions of comfort. In addition, an intra-operative assistance system will be constructed using a simulation.
NASA Astrophysics Data System (ADS)
Sriwana, I. K.; Marie, I. A.; Mangala, D.
2017-12-01
Kencana Gemilang, Co. is one electronics industry engaging in the manufacture sector. This company manufactures and assembles household electronic products, such as rice cooker, fan, iron, blender, etc. The company deals with an issue of underachievement of an established production target on MCM products line 1. This study aimed to calculate line efficiencies, delay times, and initial line smoothness indexes. The research was carried out by means of depicting a precedence diagram and gathering time data of each work element followed by examination and calculation of standard time as well as line balancing using methods of Moodie Young and Generics Algorithm. Based on results of calculation, better line balancing than the existing initial conditions, i.e. improvement in the line efficiency by 18.39%, deterioration in balanced delay by 28.39%, and deterioration of a smoothness index by 23.85% was obtained.
Echo Mapping of Active Galactic Nuclei
NASA Technical Reports Server (NTRS)
Peterson, B. M.; Horne, K.
2004-01-01
Echo mapping makes use of the intrinsic variability of the continuum source in active galactic nuclei to map out the distribution and kinematics of line-emitting gas from its light travel time-delayed response to continuum changes. Echo mapping experiments have yielded sizes for the broad line-emitting region in about three dozen AGNs. The dynamics of the line-emitting gas seem to be dominated by the gravity of the central black hole, enabling measurement of the black-hole masses in AGNs. We discuss requirements for future echo-mapping experiments that will yield the high quality velocity-delay maps of the broad-line region that are needed to determine its physical nature.
A remote instruction system empowered by tightly shared haptic sensation
NASA Astrophysics Data System (ADS)
Nishino, Hiroaki; Yamaguchi, Akira; Kagawa, Tsuneo; Utsumiya, Kouichi
2007-09-01
We present a system to realize an on-line instruction environment among physically separated participants based on a multi-modal communication strategy. In addition to visual and acoustic information, commonly used communication modalities in network environments, our system provides a haptic channel to intuitively conveying partners' sense of touch. The human touch sensation, however, is very sensitive for delays and jitters in the networked virtual reality (NVR) systems. Therefore, a method to compensate for such negative factors needs to be provided. We show an NVR architecture to implement a basic framework that can be shared by various applications and effectively deals with the problems. We take a hybrid approach to implement both data consistency by client-server and scalability by peer-to-peer models. As an application system built on the proposed architecture, a remote instruction system targeted at teaching handwritten characters and line patterns on a Korea-Japan high-speed research network also is mentioned.
JPRS Report, Science & Technology USSR: Physics & Mathematics.
1991-06-06
through a fixed delay line ( Porro prism ) and then a polarizer, the transmitted one passed through an adjustable delay line ( Porro prism ) and then a...radiation emitted by a plasma liner upon its compression into a plasma column. The target is a layer of material forming a resonance -bound ion pair...4.8338 nm wavelength corresponding to the resonance line of the 2s2 2S1/2 —> 3p 2P1/2° transition in the lithium-like A1XI ion pumping the 2s2 ’S0
Design and Performance of Ka-Band Fiber-Optic Delay Lines
2012-12-28
Approved for public release; distribution is unlimited. Vincent J. Urick Joseph M. singley christopher e. sUnderMan John F. diehl keith J...PAGES 17. LIMITATION OF ABSTRACT Design and Performance of Ka-Band Fiber-Optic Delay Lines Vincent J. Urick , Joseph M. Singley, Christopher E...Approved for public release; distribution is unlimited. Unclassified Unlimited Unclassified Unlimited Unclassified Unlimited 64 Vincent J. Urick (202
NASA Astrophysics Data System (ADS)
Kim, A. A.; Klochkov, D. V.; Konyaev, M. A.; Mihaylenko, A. S.
2017-11-01
The article considers the problem of control and verification of the laser ceilometers basic performance parameters and describes an alternative method based on the use of multi-length fiber optic delay line, simulating atmospheric track. The results of the described experiment demonstrate the great potential of this method for inspection and verification procedures of laser ceilometers.
Nonlinear calibration for petroleum water content measurement using PSO
NASA Astrophysics Data System (ADS)
Li, Mingbao; Zhang, Jiawei
2008-10-01
A new algorithmic for strapdown inertial navigation system (SINS) state estimation based on neural networks is introduced. In training strategy, the error vector and its delay are introduced. This error vector is made of the position and velocity difference between the estimations of system and the outputs of GPS. After state prediction and state update, the states of the system are estimated. After off-line training, the network can approach the status switching of SINS and after on-line training, the state estimate precision can be improved further by reducing network output errors. Then the network convergence is discussed. In the end, several simulations with different noise are given. The results show that the neural network state estimator has lower noise sensitivity and better noise immunity than Kalman filter.
Adaptive control system for line-commutated inverters
NASA Technical Reports Server (NTRS)
Dolland, C. R.; Bailey, D. A. (Inventor)
1983-01-01
A control system for a permanent magnet motor driven by a multiphase line commutated inverter is provided with integration for integrating the back EMF of each phase of the motor. This is used in generating system control signals for an inverter gate logic using a sync and firing angle (alpha) control generator connected to the outputs of the integrators. A precision full wave rectifier provides a speed control feedback signal to a phase delay rectifier via a gain and loop compensation circuit and to the integrators for adaptive control of the attenuation of low frequencies by the integrators as a function of motor speed. As the motor speed increases, the attenuation of low frequency components by the integrators is increased to offset the gain of the integrators to spurious low frequencies.
NASA Astrophysics Data System (ADS)
Trott, Wayne M.; Knudson, Marcus D.; Chhabildas, Lalit C.; Asay, James R.
2000-04-01
Relatively straightforward changes in the design of a conventional optically recording velocity interferometer system (ORVIS) can be used to produce a line-imaging instrument that allows adjustment of spatial resolution over a wide range. As a result, line-imaging ORVIS can be tailored to various specific applications involving dynamic deformation of heterogeneous materials as required by their characteristic length scales (ranging from a few μm for ferroelectric ceramics to a few mm for concrete). A line-imaging system has been successfully interfaced to a compressed gas gun driver and fielded on numerous tests in combination with simultaneous dual delay-leg, "push-pull" VISAR measurements. These tests include shock loading of glass-reinforced polyester composites, foam reverberation experiments (measurements at the free surface of a thin aluminum plate impacted by foam), and measurements of dispersive velocity in a shock-loaded explosive simulant (sugar). Results are presented that illustrate the capability for recording detailed spatially resolved material response.
Observational Requirements for High-Fidelity Reverberation Mapping
NASA Technical Reports Server (NTRS)
Horne, Keith; Peterson, Bradley M.; Collier, Stefan J.; Netzer, Hagai
2004-01-01
We present a series of simulations to demonstrate that high-fidelity velocity-delay maps of the emission-line regions in active galactic nuclei can be obtained from time-resolved spectrophotometric data sets like those that will arise from the proposed Kronos satellite. While previous reverberation-mapping experiments have established the size scale R of the broad emission-line regions from the mean time delay tau = R/c between the line and continuum variations and have provided strong evidence for supermassive black holes, the detailed structure and kinematics of the broad-line region remain ambiguous and poorly constrained. Here we outline the technical improvements that will be required to successfully map broad-line regions by reverberation techniques. For typical AGN continuum light curves, characterized by power-law power spectra P (f) is proportional to f(exp -alpha) with a = -1.5 +/- 0.5, our simulations show that a small UV/optical spectrometer like Kronos will clearly distinguish between currently viable alternative kinematic models. From spectra sampled at time intervals Delta t and sustained for a total duration T(sub dur), we can reconstruct high-fidelity velocity-delay maps with velocity resolution comparable to that of the spectra, and delay resolution Delta tau approx. 2 Delta t, provided T(sub dur) exceeds the broad-line region light crossing time by at least a factor of three. Even very complicated kinematical models, such as a Keplerian flow with superimposed spiral wave pattern, are resolved in maps from our simulated Kronos datasets. Reverberation mapping with Kronos data is therefore likely deliver the first clear maps of the geometry and kinematics in the broad emission-line regions 1-100 microarcseconds from supermassive black holes.
In-line height profiling metrology sensor for zero defect production control
NASA Astrophysics Data System (ADS)
Snel, Rob; Winters, Jasper; Liebig, Thomas; Jonker, Wouter
2017-06-01
Contemporary production systems of mechanical precision parts show challenges as increased complexity, tolerances shrinking to sub-microns and yield losses that must be mastered to the extreme. More advanced automation and process control is required to accomplish this task. Often a solution based on feedforward/feedback control is chosen requiring innovative and more advanced in line metrology. This article concentrates first on the context of in line metrology for process control and then on the development of a specific in line height profiling sensor. The novel sensor technology is based on full field time domain white light interferometry which is well know from the quality lab. The novel metrology system is to be mounted close to the production equipment, as required to minimize time delay in the control loop, and is thereby fully exposed to vibrations. This sensor is innovated to perform in line with an orders of magnitude faster throughput than laboratory instruments; it's robust to withstand the rigors of workshops and has a height resolution that is in the nanometer range.
Surface acoustic wave (SAW) vibration sensors.
Filipiak, Jerzy; Solarz, Lech; Steczko, Grzegorz
2011-01-01
In the paper a feasibility study on the use of surface acoustic wave (SAW) vibration sensors for electronic warning systems is presented. The system is assembled from concatenated SAW vibration sensors based on a SAW delay line manufactured on a surface of a piezoelectric plate. Vibrations of the plate are transformed into electric signals that allow identification of the sensor and localization of a threat. The theoretical study of sensor vibrations leads us to the simple isotropic model with one degree of freedom. This model allowed an explicit description of the sensor plate movement and identification of the vibrating sensor. Analysis of frequency response of the ST-cut quartz sensor plate and a damping speed of its impulse response has been conducted. The analysis above was the basis to determine the ranges of parameters for vibrating plates to be useful in electronic warning systems. Generally, operation of electronic warning systems with SAW vibration sensors is based on the analysis of signal phase changes at the working frequency of delay line after being transmitted via two circuits of concatenated four-terminal networks. Frequencies of phase changes are equal to resonance frequencies of vibrating plates of sensors. The amplitude of these phase changes is proportional to the amplitude of vibrations of a sensor plate. Both pieces of information may be sent and recorded jointly by a simple electrical unit.
USDA-ARS?s Scientific Manuscript database
Growing heat sensitive soybean under the high heat and humid environment of the Early Soybean Production System (ESPS) in the Midsouthern USA often leads to poor seed quality. Therefore, breeding for heat tolerant soybeans that maintain high quality of seed nutrition, high germination, and high prot...
Gravitational lens system SDSS J1339+1310: microlensing factory and time delay
NASA Astrophysics Data System (ADS)
Goicoechea, L. J.; Shalyapin, V. N.
2016-12-01
We spectroscopically re-observed the gravitational lens system SDSS J1339+1310 using OSIRIS on the GTC. We also monitored the r-band variability of the two quasar images (A and B) with the LT over 143 epochs in the period 2009-2016. These new data in both the wavelength and time domains have confirmed that the system is an unusual microlensing factory. The C iv emission line is remarkably microlensed, since the microlensing magnification of B relative to that for A, μBA, reaches a value of 1.4 ( 0.4 mag) for its core. Moreover, the B image shows a red wing enhancement of C iv flux (relative to A), and μBA = 2 (0.75 mag) for the C iv broad-line emission. Regarding the nuclear continuum, we find a chromatic behaviour of μBA, which roughly varies from 5 (1.75 mag) at 7000 Å to 6 (1.95 mag) at 4000 Å. We also detect significant microlensing variability in the r band, and this includes a number of microlensing events on timescales of 50-100 d. Fortunately, the presence of an intrinsic 0.7 mag dip in the light curves of A and B, permitted us to measure the time delay between both quasar images. This delay is ΔtAB = 47 d (1σ confidence interval; A is leading), in good agreement with predictions of lens models. Tables 1-3 are only available at the CDS via anonymous ftp to http://cdsarc.u-strasbg.fr (http://130.79.128.5) or via http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/596/A77
NASA Astrophysics Data System (ADS)
Verhaegen, Staf; Nackaerts, Axel; Dusa, Mircea; Carpaij, Rene; Vandenberghe, Geert; Finders, Jo
2006-03-01
The purpose of this paper is to use measurements on real working devices to derive more information than typically measured by the classic line-width measurement techniques. The first part of the paper will discuss the principle of the measurements with a ring oscillator, a circuit used to measure the speed of elementary logic gates. These measurements contribute to the understanding of the exact timing dependencies in circuits, which is of utmost importance for the design and simulation of these circuits. When connecting an odd number of digital inverting stages in a ring, the circuit has no stable digital state but acts as an analog oscillator with the oscillation frequency dependent on the analog propagation delay of the signals through the stages. By varying some conditions during a litho step, the delay change caused by the process condition change can be measured very accurately. The response of the ring oscillator delay to exposure dose is measured and presented in this paper together with a comparison of measured line-width values of the poly gate lines. The second part of the paper will focus on improving the intra-wafer variation of the stage delay. A number of ring oscillators are put in a design at different slit and scan locations. 200mm wafers are processed with 48 full dies present. From the intra-wafer delay fingerprint and the dose sensitivity of the delay an intra-wafer dose correction, also called a dose recipe, is calculated. This dose recipe is used on the scanner to compensate for effects that are the root cause for the delay profile; including reticle and processing such as track, etch and annealing.
A signal-flow-graph approach to on-line gradient calculation.
Campolucci, P; Uncini, A; Piazza, F
2000-08-01
A large class of nonlinear dynamic adaptive systems such as dynamic recurrent neural networks can be effectively represented by signal flow graphs (SFGs). By this method, complex systems are described as a general connection of many simple components, each of them implementing a simple one-input, one-output transformation, as in an electrical circuit. Even if graph representations are popular in the neural network community, they are often used for qualitative description rather than for rigorous representation and computational purposes. In this article, a method for both on-line and batch-backward gradient computation of a system output or cost function with respect to system parameters is derived by the SFG representation theory and its known properties. The system can be any causal, in general nonlinear and time-variant, dynamic system represented by an SFG, in particular any feedforward, time-delay, or recurrent neural network. In this work, we use discrete-time notation, but the same theory holds for the continuous-time case. The gradient is obtained in a straightforward way by the analysis of two SFGs, the original one and its adjoint (obtained from the first by simple transformations), without the complex chain rule expansions of derivatives usually employed. This method can be used for sensitivity analysis and for learning both off-line and on-line. On-line learning is particularly important since it is required by many real applications, such as digital signal processing, system identification and control, channel equalization, and predistortion.
A methodology based on reduced complexity algorithm for system applications using microprocessors
NASA Technical Reports Server (NTRS)
Yan, T. Y.; Yao, K.
1988-01-01
The paper considers a methodology on the analysis and design of a minimum mean-square error criterion linear system incorporating a tapped delay line (TDL) where all the full-precision multiplications in the TDL are constrained to be powers of two. A linear equalizer based on the dispersive and additive noise channel is presented. This microprocessor implementation with optimized power of two TDL coefficients achieves a system performance comparable to the optimum linear equalization with full-precision multiplications for an input data rate of 300 baud.
SAW devices for consumer communication applications.
Ruppel, C W; Dill, R; Fischerauer, A; Fischerauer, G; Gawlik, A; Machui, J; Muller, F; Reindl, L; Ruile, W; Scholl, G; Schropp, I; Wagner, K C
1993-01-01
An overview of surface acoustic wave (SAW) filter techniques available for different applications is given. Techniques for TV IF applications are outlined, and typical structures are presented. This is followed by a discussion of applications for SAW resonators. Low-loss devices for mobile communication systems and pager applications are examined. Tapped delay lines (matched filters) and convolvers for code-division multiaccess (CDMA) systems are also covered. Although simulation procedures are not considered, for many devices the theoretical frequency response is presented along with the measurement curve.
Testing Delays Resulting in Increased Identification Accuracy in Line-Ups and Show-Ups.
ERIC Educational Resources Information Center
Dekle, Dawn J.
1997-01-01
Investigated time delays (immediate, two-three days, one week) between viewing a staged theft and attempting an eyewitness identification. Compared lineups to one-person showups in a laboratory analogue involving 412 subjects. Results show that across all time delays, participants maintained a higher identification accuracy with the showup…
NASA Astrophysics Data System (ADS)
Lin, Gong-Ru
2002-12-01
We develop a delay-line-free and frequency traceable electro-optic sampling oscilloscope by use of a digital phase-locked loop phase shifter (PLL-PS) controlled delay-time-tunable gain-switched laser diode (GSLD). The home-made voltage-controllable PLL-PS exhibits a linear transfer function with ultra-wide phase shifting range of ±350° and tuning error of <±5%, which benefits the advantages of frequency tracking to free-running signals with suppressed timing-jitter. The maximum delay-time of PLL-PS controlled GSLD is up to 1.95 periods by changing the controlling voltage ( VREF) from -3.5 to 3.5 V, which corresponds to 3.9 ns at repetition frequency of 500 MHz. The tuning responsivity and resolution are about 0.56 ns/V and 0.15˜0.2 ps, respectively. The maximum delay-time switching bandwidth of 100 Hz is determined under the control of a saw-tooth modulated VREF function. The waveform sampling of microwave PECL signals generated from a free-running digital frequency divider is performed with acceptable measuring deviation.
Space applications for high temperature superconductivity - Brief review
NASA Technical Reports Server (NTRS)
Krishen, Kumar
1990-01-01
An overview is presented of materials and devices based on high-temperature superconductivity (HTS) that could have useful space-oriented applications. Of specific interest are applications of HTS technologies to mm and microwave systems, spaceborne and planet-surface sensors, and to magnetic subsystems for robotic, rescue, and docking maneuvers. HTS technologies can be used in optoelectronics, magnetic-field detectors, antennae, transmission/delay lines, and launch/payload coils.
Cheema, Parneet K; Menjak, Ines B; Winterton-Perks, Zoe; Raphael, Simon; Cheng, Susanna Y; Verma, Sunil; Muinuddin, Ahmad; Freedman, Ryan; Toor, Nevkeet; Perera, Joseph; Anaka, Matthew; Victor, J Charles
2017-02-01
Optimal first-line systemic therapy for patients with advanced nonsquamous (nonsq) non-small-cell lung cancer (NSCLC) requires confirmation of EGFR/ ALK status, which can delay treatment. We evaluated the impact of reflex testing, defined as pathologists initiating EGFR/ ALK testing at the time of diagnosis of nonsq NSCLC, on time to treatment (TTT). We conducted a retrospective review of patients with nonsq NSCLC with medical oncology consultation at Sunnybrook Odette Cancer Centre between March 18, 2010 and April 30, 2014. Data were compared during routine and reflex testing. TTT was defined as the interval between the first medical oncology visit with advanced NSCLC and the initiation of systemic therapy. A total of 306 patients were included (n = 232 for routine testing, n = 74 for reflex testing). There was a trend to improvement in median TTT with reflex testing (36 days [interquartile range {IQR}, 16 to 71 days v 26 days [IQR, 8 to 41 days], P = .071). Omitting patients with intentional delays in systemic therapy for low-volume disease, poor performance status, comorbidity management, and/or radiation therapy, median TTT improved (34 days [IQR, 15 to 67 days] v 22 days [IQR, 8 to 42 days], P = .049). Time to optimal first-line systemic therapy according to published guidelines improved (median, 36 days [IQR, 16 to 91 days] v 24 days [IQR, 8 to 43 days], P = .036). There was no impact on receipt of any first-line systemic therapy (55% v 59%, P = .66). The quality of biomarker testing improved, with fewer unsuccessful tests ( EGFR, 14% v 4%, P = .039; and ALK, 17% v 3%, P = .037). Reflex testing of EGFR/ ALK improved the time to optimal systemic therapy and the quality of biomarker testing for patients with advanced nonsq NSCLC.
NASA Astrophysics Data System (ADS)
Cai, Feida; Li, Honglang; Tian, Yahui; Ke, Yabing; Cheng, Lina; Lou, Wei; He, Shitang
2018-03-01
Line-defect piezoelectric phononic crystals (PCs) show good potential applications in surface acoustic wave (SAW) MEMS devices for RF communication systems. To analyze the SAW characteristics in line-defect two-dimensional (2D) piezoelectric PCs, optical methods are commonly used. However, the optical instruments are complex and expensive, whereas conventional electrical methods can only measure SAW transmission of the whole device and lack spatial resolution. In this paper, we propose a new electrical experimental method with multiple receiving interdigital transducers (IDTs) to detect the SAW field distribution, in which an array of receiving IDTs of equal aperture was used to receive the SAW. For this new method, SAW delay lines with perfect and line-defect 2D Al/128°YXLiNbO3 piezoelectric PCs on the transmitting path were designed and fabricated. The experimental results showed that the SAW distributed mainly in the line-defect region, which agrees with the theoretical results.
Radiation hard programmable delay line for LHCb calorimeter upgrade
NASA Astrophysics Data System (ADS)
Mauricio, J.; Gascón, D.; Vilasís, X.; Picatoste, E.; Machefert, F.; Lefrancois, J.; Duarte, O.; Beigbeder, C.
2014-01-01
This paper describes the implementation of a SPI-programmable clock delay chip based on a Delay Locked Loop (DLL) in order to shift the phase of the LHC clock (25 ns) in steps of 1ns, with less than 5 ps jitter and 23 ps of DNL. The delay lines will be integrated into ICECAL, the LHCb calorimeter front-end analog signal processing ASIC in the near future. The stringent noise requirements on the ASIC imply minimizing the noise contribution of digital components. This is accomplished by implementing the DLL in differential mode. To achieve the required radiation tolerance several techniques are applied: double guard rings between PMOS and NMOS transistors as well as glitch suppressors and TMR Registers. This 5.7 mm2 chip has been implemented in CMOS 0.35 μm technology.
Evaluation of the Affymetrix CytoScan® Dx Assay for Developmental Delay
Webb, Bryn D.; Scharf, Rebecca J.; Spear, Emily A.; Edelmann, Lisa J.; Stroustrup, Annemarie
2015-01-01
The goal of molecular cytogenetic testing for children presenting with developmental delay is to identify or exclude genetic abnormalities that are associated with cognitive, behavioral, and/or motor symptoms. Until 2010, chromosome analysis was the standard first-line genetic screening test for evaluation of patients with developmental delay when a specific syndrome was not suspected. In 2010, The American College of Medical Genetics and several other groups recommended chromosomal microarray (CMA) as the first-line test in children with developmental delays, multiple congenital anomalies, and/or autism. This test is able to detect regions of genomic imbalances at a much finer resolution than G-banded karyotyping. Until recently, no CMA testing had been approved by the United States Food and Drug Administration (FDA). This review will focus on the use of the Affymetrix CytoScan® Dx Assay, the first CMA to receive FDA approval for the genetic evaluation of individuals with developmental delay. PMID:25350348
Castells-Sarret, Neus; Cueto-González, Anna M; Borregan, Mar; López-Grondona, Fermina; Miró, Rosa; Tizzano, Eduardo; Plaja, Alberto
2017-09-25
Conventional cytogenetics diagnoses 3-5% of patients with unexplained developmental delay/intellectual disability and/or multiple congenital anomalies. The Multiplex Ligation-dependent Probe Amplification increases diagnostic rates from between 2.4 to 5.8%. Currently the comparative genomic hybridisation array or aCGH is the highest performing diagnostic tool in patients with developmental delay/intellectual disability, congenital anomalies and autism spectrum disorders. Our aim is to evaluate the efficiency of the use of aCGH as first-line test in these and other indications (epilepsy, short stature). A total of 1000 patients referred due to one or more of the abovementioned disorders were analysed by aCGH. Pathogenic genomic imbalances were detected in 14% of the cases, with a variable distribution of diagnosis according to the phenotypes: 18.9% of patients with developmental delay/intellectual disability; 13.7% of multiple congenital anomalies, 9.76% of psychiatric pathologies, 7.02% of patients with epilepsy, and 13.3% of patients with short stature. Within the multiple congenital anomalies, central nervous system abnormalities and congenital heart diseases accounted for 14.9% and 10.6% of diagnoses, respectively. Among the psychiatric disorders, patients with autism spectrum disorders accounted for 8.9% of the diagnoses. Our results demonstrate the effectiveness and efficiency of the use of aCGH as the first line test in genetic diagnosis of patients suspected of genomic imbalances, supporting its inclusion within the National Health System. Copyright © 2017. Publicado por Elsevier España, S.L.U.
Nuclear reactor with internal thimble-type delayed neutron detection system
Gross, Kenny C.; Poloncsik, John; Lambert, John D. B.
1990-01-01
This invention teaches improved apparatus for the method of detecting a breach in cladded fuel used in a nuclear reactor. The detector apparatus is located in the primary heat exchanger which conveys part of the reactor coolant past at least three separate delayed-neutron detectors mounted in this heat exchanger. The detectors are spaced apart such that the coolant flow time from the core to each detector is different, and these differences are known. The delayed-neutron activity at the detectors is a function of the delay time after the reaction in the fuel until the coolant carrying the delayed-neutron emitter passes the respective detector. This time delay is broken down into separate components including an isotopic holdup time required for the emitter to move through the fuel from the reaction to the coolant at the breach, and two transit times required for the emitter now in the coolant to flow from the breach to the detector loop and then via the loop to the detector. At least two of these time components are determined during calibrated operation of the reactor. Thereafter during normal reactor operation, repeated comparisons are made by the method of regression approximation of the third time component for the best-fit line correlating measured delayed-neutron activity against activity that is approximated according to specific equations. The equations use these time-delay components and known parameter values of the fuel and of the part and emitting daughter isotopes.
Analysis of Photonic Phase-Shifting Technique Employing Amplitude-Controlled Fiber-Optic Delay Lines
2012-01-13
Controlled Fiber-Optic Delay Lines January 13, 2012 Approved for public release; distribution is unlimited. Meredith N. draa ViNceNt J. Urick keith J...Draa, Vincent J. Urick , and Keith J. Williams Naval Research Laboratory, Code 5652 4555 Overlook Avenue, SW Washington, DC 20375-5320 NRL/MR/5650--12...9376 Approved for public release; distribution is unlimited. Unclassified Unclassified Unclassified UU 29 Vincent J. Urick (202) 767-9352 Fiber optics
Arrival Metering Precision Study
NASA Technical Reports Server (NTRS)
Prevot, Thomas; Mercer, Joey; Homola, Jeffrey; Hunt, Sarah; Gomez, Ashley; Bienert, Nancy; Omar, Faisal; Kraut, Joshua; Brasil, Connie; Wu, Minghong, G.
2015-01-01
This paper describes the background, method and results of the Arrival Metering Precision Study (AMPS) conducted in the Airspace Operations Laboratory at NASA Ames Research Center in May 2014. The simulation study measured delivery accuracy, flight efficiency, controller workload, and acceptability of time-based metering operations to a meter fix at the terminal area boundary for different resolution levels of metering delay times displayed to the air traffic controllers and different levels of airspeed information made available to the Time-Based Flow Management (TBFM) system computing the delay. The results show that the resolution of the delay countdown timer (DCT) on the controllers display has a significant impact on the delivery accuracy at the meter fix. Using the 10 seconds rounded and 1 minute rounded DCT resolutions resulted in more accurate delivery than 1 minute truncated and were preferred by the controllers. Using the speeds the controllers entered into the fourth line of the data tag to update the delay computation in TBFM in high and low altitude sectors increased air traffic control efficiency and reduced fuel burn for arriving aircraft during time based metering.
Electrical delay line multiplexing for pulsed mode radiation detectors
NASA Astrophysics Data System (ADS)
Vinke, Ruud; Yeom, Jung Yeol; Levin, Craig S.
2015-04-01
Medical imaging systems are composed of a large number of position sensitive radiation detectors to provide high resolution imaging. For example, whole-body Positron Emission Tomography (PET) systems are typically composed of thousands of scintillation crystal elements, which are coupled to photosensors. Thus, PET systems greatly benefit from methods to reduce the number of data acquisition channels, in order to reduce the system development cost and complexity. In this paper we present an electrical delay line multiplexing scheme that can significantly reduce the number of readout channels, while preserving the signal integrity required for good time resolution performance. We experimented with two 4 × 4 LYSO crystal arrays, with crystal elements having 3 mm × 3 mm × 5 mm and 3 mm × 3 mm × 20 mm dimensions, coupled to 16 Hamamatsu MPPC S10931-050P SiPM elements. Results show that each crystal could be accurately identified, even in the presence of scintillation light sharing and inter-crystal Compton scatter among neighboring crystal elements. The multiplexing configuration degraded the coincidence timing resolution from ∼243 ps FWHM to ∼272 ps FWHM when 16 SiPM signals were combined into a single channel for the 4 × 4 LYSO crystal array with 3 mm × 3 mm × 20 mm crystal element dimensions, in coincidence with a 3 mm × 3 mm × 5 mm LYSO crystal pixel. The method is flexible to allow multiplexing configurations across different block detectors, and is scalable to an entire ring of detectors.
Zebrafish hair cell mechanics and physiology through the lens of noise-induced hair cell death
NASA Astrophysics Data System (ADS)
Coffin, Allison B.; Xu, Jie; Uribe, Phillip M.
2018-05-01
Hair cells are exquisitely sensitive to auditory stimuli, but also to damage from a variety of sources including noise trauma and ototoxic drugs. Mammals cannot regenerate cochlear hair cells, while non-mammalian vertebrates exhibit robust regenerative capacity. Our research group uses the lateral line system of larval zebrafish to explore the mechanisms underlying hair cell damage, identify protective therapies, and determine molecular drivers of innate regeneration. The lateral line system contains externally located sensory organs called neuromasts, each composed of ˜8-20 hair cells. Lateral line hair cells are homologous to vertebrate inner ear hair cells and share similar susceptibility to ototoxic damage. In the last decade, the lateral line has emerged as a powerful model system for understanding hair cell death mechanisms and for identifying novel protective compounds. Here we demonstrate that the lateral line is a tractable model for noise-induced hair cell death. We have developed a novel noise damage system capable of inducing over 50% loss of lateral line hair cells, with hair cell death occurring in a dose- and time-dependent manner. Cell death is greatest 72 hours post-exposure. However, early signs of hair cell damage, including changes in membrane integrity and reduced mechanotransduction, are apparent within hours of noise exposure. These features, early signs of damage followed by delayed hair cell death, are consistent with mammalian data, suggesting that noise acts similarly on zebrafish and mammalian hair cells. In our future work we will use our new model system to investigate noise damage events in real time, and to develop protective therapies for future translational research.
High-speed line-scan camera with digital time delay integration
NASA Astrophysics Data System (ADS)
Bodenstorfer, Ernst; Fürtler, Johannes; Brodersen, Jörg; Mayer, Konrad J.; Eckel, Christian; Gravogl, Klaus; Nachtnebel, Herbert
2007-02-01
Dealing with high-speed image acquisition and processing systems, the speed of operation is often limited by the amount of available light, due to short exposure times. Therefore, high-speed applications often use line-scan cameras, based on charge-coupled device (CCD) sensors with time delayed integration (TDI). Synchronous shift and accumulation of photoelectric charges on the CCD chip - according to the objects' movement - result in a longer effective exposure time without introducing additional motion blur. This paper presents a high-speed color line-scan camera based on a commercial complementary metal oxide semiconductor (CMOS) area image sensor with a Bayer filter matrix and a field programmable gate array (FPGA). The camera implements a digital equivalent to the TDI effect exploited with CCD cameras. The proposed design benefits from the high frame rates of CMOS sensors and from the possibility of arbitrarily addressing the rows of the sensor's pixel array. For the digital TDI just a small number of rows are read out from the area sensor which are then shifted and accumulated according to the movement of the inspected objects. This paper gives a detailed description of the digital TDI algorithm implemented on the FPGA. Relevant aspects for the practical application are discussed and key features of the camera are listed.
NASA Astrophysics Data System (ADS)
Lippert, G.; Bluhm, K. H.; Malzahn, P.; Bulka, C.
1985-12-01
For communication between geostationary satellites a transmitter using a TWT amplifier with frequencies in the region of 60 GHz and output power of a few watts is proposed. The design objectives for the electron gun were realized using a computer program, which also takes into account the thermal velocities of the electrons, to dimension the electrodes. A focusing electrode and a mixed metal cathode with a low beam compression ratio are employed in the gun. All requirements for the beam focusing system are met using an extremely precise machined integrated PPM system and SmCo5 magnets. An easily manufacturable delay line structure was realized using a diffusion brazed interdigital line consisting of only a few parts. The one stage collector can operate with a strongly reduced potential.
Measuring a Fiber-Optic Delay Line Using a Mode-Locked Laser
NASA Technical Reports Server (NTRS)
Tu, Meirong; McKee, Michael R.; Pak, Kyung S.; Yu, Nan
2010-01-01
The figure schematically depicts a laboratory setup for determining the optical length of a fiber-optic delay line at a precision greater than that obtainable by use of optical time-domain reflectometry or of mechanical measurement of length during the delay-line-winding process. In this setup, the delay line becomes part of the resonant optical cavity that governs the frequency of oscillation of a mode-locked laser. The length can then be determined from frequency-domain measurements, as described below. The laboratory setup is basically an all-fiber ring laser in which the delay line constitutes part of the ring. Another part of the ring - the laser gain medium - is an erbium-doped fiber amplifier pumped by a diode laser at a wavelength of 980 nm. The loop also includes an optical isolator, two polarization controllers, and a polarizing beam splitter. The optical isolator enforces unidirectional lasing. The polarization beam splitter allows light in only one polarization mode to pass through the ring; light in the orthogonal polarization mode is rejected from the ring and utilized as a diagnostic output, which is fed to an optical spectrum analyzer and a photodetector. The photodetector output is fed to a radio-frequency spectrum analyzer and an oscilloscope. The fiber ring laser can generate continuous-wave radiation in non-mode-locked operation or ultrashort optical pulses in mode-locked operation. The mode-locked operation exhibited by this ring is said to be passive in the sense that no electro-optical modulator or other active optical component is used to achieve it. Passive mode locking is achieved by exploiting optical nonlinearity of passive components in such a manner as to obtain ultra-short optical pulses. In this setup, the particular nonlinear optical property exploited to achieve passive mode locking is nonlinear polarization rotation. This or any ring laser can support oscillation in multiple modes as long as sufficient gain is present to overcome losses in the ring. When mode locking is achieved, oscillation occurs in all the modes having the same phase and same polarization. The frequency interval between modes, often denoted the free spectral range (FSR), is given by c/nL, where c is the speed of light in vacuum, n is the effective index of refraction of the fiber, and L is the total length of optical path around the ring. Therefore, the length of the fiber-optic delay line, as part of the length around the ring, can be calculated from the FSRs measured with and without the delay line incorporated into the ring. For this purpose, the FSR measurements are made by use of the optical and radio-frequency spectrum analyzers. In experimentation on a 10-km-long fiber-optic delay line, it was found that this setup made it possible to measure the length to within a fractional error of about 3 10(exp -6), corresponding to a length error of 3 cm. In contrast, measurements by optical time-domain reflectometry and mechanical measurement were found to be much less precise: For optical time-domain reflectometry, the fractional error was found no less than 10(exp -4) (corresponding to a length error of 1 m) and for mechanical measurement, the fractional error was found to be about 10(exp -2) (corresponding to a length error of 100 m).
Delayed temporal discrimination in pigeons: A comparison of two procedures
Chatlosh, Diane L.; Wasserman, Edward A.
1987-01-01
A within-subjects comparison was made of pigeons' performance on two temporal discrimination procedures that were signaled by differently colored keylight samples. During stimulus trials, a peck on the key displaying a slanted line was reinforced following short keylight samples, and a peck on the key displaying a horizontal line was reinforced following long keylight samples, regardless of the location of the stimuli on those two choice keys. During position trials, a peck on the left key was reinforced following short keylight samples and a peck on the right key was reinforced following long keylight samples, regardless of which line stimulus appeared on the correct key. Thus, on stimulus trials, the correct choice key could not be discriminated prior to the presentation of the test stimuli, whereas on position trials, the correct choice key could be discriminated during the presentation of the sample stimulus. During Phase 1, with a 0-s delay between sample and choice stimuli, discrimination learning was faster on position trials than on stimulus trials for all 4 birds. During Phase 2, 0-, 0.5-, and 1.0-s delays produced differential loss of stimulus control under the two tasks for 2 birds. Response patterns during the delay intervals provided some evidence for differential mediation of the two delayed discriminations. These between-task differences suggest that the same processes may not mediate performance in each. PMID:16812483
A liquid lens switching-based motionless variable fiber-optic delay line
NASA Astrophysics Data System (ADS)
Khwaja, Tariq Shamim; Reza, Syed Azer; Sheikh, Mumtaz
2018-05-01
We present a Variable Fiber-Optic Delay Line (VFODL) module capable of imparting long variable delays by switching an input optical/RF signal between Single Mode Fiber (SMF) patch cords of different lengths through a pair of Electronically Controlled Tunable Lenses (ECTLs) resulting in a polarization-independent operation. Depending on intended application, the lengths of the SMFs can be chosen accordingly to achieve the desired VFODL operation dynamic range. If so desired, the state of the input signal polarization can be preserved with the use of commercially available polarization-independent ECTLs along with polarization-maintaining SMFs (PM-SMFs), resulting in an output polarization that is identical to the input. An ECTL-based design also improves power consumption and repeatability. The delay switching mechanism is electronically-controlled, involves no bulk moving parts, and can be fully-automated. The VFODL module is compact due to the use of small optical components and SMFs that can be packaged compactly.
NASA Astrophysics Data System (ADS)
Tang, Huijuan; Hao, Xiaojian; Hu, Xiaotao
2018-01-01
In the case of conventional contact temperature measurement, there is a delay phenomenon and high temperature resistant materials limitation. By using the faster response speed and theoretically no upper limit of the non-contact temperature method, the measurement system based on the principle of double line atomic emission spectroscopy temperature measurement is put forward, the structure and theory of temperature measuring device are introduced. According to the atomic spectrum database (ASD), Aluminum(Al) I 690.6 nm and Al I 708.5 nm are selected as the two lines in the temperature measurement. The intensity ratio of the two emission lines was measured by a spectrometer to obtain the temperature of Al burning in pure oxygen, and the result compared to the temperature measured by the thermocouple. It turns out that the temperature correlation between the two methods is good, and it proves the feasibility of the method.
A position- and time-sensitive photon-counting detector with delay- line read-out
NASA Astrophysics Data System (ADS)
Jagutzki, Ottmar; Dangendorf, Volker; Lauck, Ronald; Czasch, Achim; Milnes, James
2007-05-01
We have developed image intensifier tubes with delay-anode read-out for time- and position-sensitive photon counting. The timing precision is better than 1 ns with 1000x1000 pixels position resolution and up to one megacounts/s processing rate. Large format detectors of 40 and 75 mm active diameter with internal helical-wire delay-line anodes have been produced and specified. A different type of 40 and 25 mm tubes with semi-conducting screen for image charge read-out allow for an economic and robust tube design and for placing the read-out anodes outside the sealed housing. Two types of external delay-line anodes, i.e. pick-up electrodes for the image charge, have been tested. We present tests of the detector and anode performance. Due to the low background this technique is well suited for applications with very low light intensity and especially if a precise time tagging for each photon is required. As an example we present the application of scintillator read-out in time-of-flight (TOF) neutron radiography. Further applications so far are Fluorescence Life-time Microscopy (FLIM) and Astronomy.
Characteristics of gamma-ray line flares
NASA Technical Reports Server (NTRS)
Bai, T.; Dennis, B.
1983-01-01
Observations of solar gamma rays by the Solar Maximum Mission (SMM) demonstrate that energetic protons and ions are rapidly accelerated during the impulsive phase. To understand the acceleration mechanisms for these particles, the characteristics of the gamma ray line flares observed by SMM were studied. Some very intense hard X-ray flares without detectable gamma ray lines were also investigated. Gamma ray line flares are distinguished from other flares by: (1) intense hard X-ray and microwave emissions; (2) delay of high energy hard X-rays; (3) emission of type 2 and/or type 4 radio bursts; and (4) flat hard X-ray spectra (average power law index: 3.1). The majority of the gamma ray line flares shared all these characteristics, and the remainder shared at least three of them. Positive correlations were found between durations of spike bursts and spatial sizes of flare loops as well as between delay times and durations of spike bursts.
Endpoint Naming for Space Delay/Disruption Tolerant Networking
NASA Technical Reports Server (NTRS)
Clare, Loren; Burleigh, Scott; Scott, Keith
2010-01-01
Delay/Disruption Tolerant Networking (DTN) provides solutions to space communication challenges such as disconnections when orbiters lose line-of-sight with landers, long propagation delays over interplanetary links, and other operational constraints. DTN is critical to enabling the future space internetworking envisioned by NASA. Interoperability with international partners is essential and standardization is progressing through both the CCSDS and the IETF.
Electronic Combat Hardware-in-the-Loop Testing in an Open Air Environment
1994-09-01
APQ- 126 (F-111) Gun Dish Squat Eye ANAWG-9 (F-14) Grill Pan Straight Flush I-Hawk Hawk Screech Sun Visor Head Light Tall King High Fix Team Work High...the required delay to the IF, the SPCs contain a Teledyne Microwave Bulk Acoustic Wave (BAW) delay line as well as a Coherent Variable Delay Unit
NASA Astrophysics Data System (ADS)
Moralis-Pegios, M.; Terzenidis, N.; Mourgias-Alexandris, G.; Vyrsokinos, K.; Pleros, N.
2018-02-01
Disaggregated Data Centers (DCs) have emerged as a powerful architectural framework towards increasing resource utilization and system power efficiency, requiring, however, a networking infrastructure that can ensure low-latency and high-bandwidth connectivity between a high-number of interconnected nodes. This reality has been the driving force towards high-port count and low-latency optical switching platforms, with recent efforts concluding that the use of distributed control architectures as offered by Broadcast-and-Select (BS) layouts can lead to sub-μsec latencies. However, almost all high-port count optical switch designs proposed so far rely either on electronic buffering and associated SerDes circuitry for resolving contention or on buffer-less designs with packet drop and re-transmit procedures, unavoidably increasing latency or limiting throughput. In this article, we demonstrate a 256x256 optical switch architecture for disaggregated DCs that employs small-size optical delay line buffering in a distributed control scheme, exploiting FPGA-based header processing over a hybrid BS/Wavelength routing topology that is implemented by a 16x16 BS design and a 16x16 AWGR. Simulation-based performance analysis reveals that even the use of a 2- packet optical buffer can yield <620nsec latency with >85% throughput for up to 100% loads. The switch has been experimentally validated with 10Gb/s optical data packets using 1:16 optical splitting and a SOA-MZI wavelength converter (WC) along with fiber delay lines for the 2-packet buffer implementation at every BS outgoing port, followed by an additional SOA-MZI tunable WC and the 16x16 AWGR. Error-free performance in all different switch input/output combinations has been obtained with a power penalty of <2.5dB.
All-optical single-sideband frequency upconversion utilizing the XPM effect in an SOA-MZI.
Kim, Doo-Ho; Lee, Joo-Young; Choi, Hyung-June; Song, Jong-In
2016-09-05
An all-optical single sideband (OSSB) frequency upconverter based on the cross-phase modulation (XPM) effect is proposed and experimentally demonstrated to overcome the power fading problem caused by the chromatic dispersion of fiber in radio-over-fiber systems. The OSSB frequency upconverter consists of an arrayed waveguide grating (AWG) and a semiconductor optical amplifier Mach-Zehnder interferometer (SOA-MZI) and does not require an extra delay line used for phase noise compensation. The generated OSSB radio frequency (RF) signal transmitted over single-mode fibers up to 20 km shows a flat electrical RF power response as a function of the fiber length. The upconverted electrical RF signal at 48 GHz shows negligible degradation of the phase noise even without an extra delay line. The measured phase noise of the upconverted RF signal (48 GHz) is -74.72 dBc/Hz at an offset frequency of 10 kHz. The spurious free dynamic range (SFDR) measured by a two-tone test to estimate the linearity of the OSSB frequency upconverter is 72.5 dB·Hz2/3.
Dispersion control with a Fourier-domain optical delay line in a fiber-optic imaging interferometer.
Lee, Kye-Sung; Akcay, A Ceyhun; Delemos, Tony; Clarkson, Eric; Rolland, Jannick P
2005-07-01
Recently, Fourier-domain (FD) optical delay lines (ODLs) were introduced for high-speed scanning and dispersion compensation in imaging interferometry. We investigate the effect of first- and second-order dispersion on the photocurrent signal associated with an optical coherence imaging system implemented with a single-mode fiber, a superluminescent diode centered at 950 nm +/- 35 nm, a FD ODL, a mirror, and a layered LiTAO3 that has suitable dispersion characteristics to model a skin specimen. We present a practical and useful method to minimize the effect of dispersion through the interferometer and the specimen combined, as well as to quantify the results using two general metrics for resolution. Theoretical and associated experimental results show that, under the optimum solution, the maximum broadening of the point-spread function through a 1-mm-deep specimen is limited to 57% of its original rms width value (i.e., 8.1 microm optimal, 12.7 microm at maximum broadening) compared with approximately 110% when compensation is performed without the specimen taken into account.
Magnonic crystal as a delay line for low-noise auto-oscillators
DOE Office of Scientific and Technical Information (OSTI.GOV)
Bankowski, Elena; Meitzler, Thomas; Khymyn, Roman S., E-mail: khiminr@gmail.com
2015-09-21
It is demonstrated that a delay line based on a one-dimensional magnonic crystal used in a feedback loop of a microwave auto-oscillator can substantially reduce the phase noise figure and improve other vital performance characteristics of the auto-oscillator. The advantage is achieved due to the increase of the effective delay time in the magnonic crystal, compared to the case of an un-patterned yttrium iron garnet (YIG) film, and improvement of the power-handling characteristics due to the now possible increase of the YIG film thickness. The internal modes of a magnonic crystal caused by the periodic energy exchange between the incidentmore » and reflected spin waves play the dominant role in the described effect.« less
Chakraborty, Arup Lal; Ruxton, Keith; Johnstone, Walter; Lengden, Michael; Duffin, Kevin
2009-06-08
A new fiber-optic technique to eliminate residual amplitude modulation in tunable diode laser wavelength modulation spectroscopy is presented. The modulated laser output is split to pass in parallel through the gas measurement cell and an optical fiber delay line, with the modulation frequency / delay chosen to introduce a relative phase shift of pi between them. The two signals are balanced using a variable attenuator and recombined through a fiber coupler. In the absence of gas, the direct laser intensity modulation cancels, thereby eliminating the high background. The presence of gas induces a concentration-dependent imbalance at the coupler's output from which the absolute absorption profile is directly recovered with high accuracy using 1f detection.
S-band SBAW microwave source, phase 2
NASA Technical Reports Server (NTRS)
1983-01-01
Results of aging experiments on 1.072 GHz SBAW oscillators are discussed as well as the design, fabrication and test of 2.143 GHz SBAW delay lines. Two design approaches were implemented. The third harmonic transducer on 36 deg rotated Y cut quartz proved to be the most useful design, whereas the fifth harmonic transducer on - 50 5 deg rotated Y cut quartz suffered from high insertion loss and poor sidelobe rejection. The construction and characterization of the 2 GHz SBAW oscillator are described. Phase noise, frequency dependence on temperature, and 6-month aging were measured. Some SAW and SBAW oscillators were compared as were both the 1 and 2 GHz oscillators. The 2 GHz SBAW oscillator showed significant improvement in phase noise and temperature stability over the 2 GHz SAW oscillator developed in previous NASA programs. A technique to produce SBAW delay lines of different frequencies from a single mask is examined. The delay lines were incorporated into oscillator circuits to demonstrate the ability to select the frequency output of the SBAW oscillator.
High-speed MCP anodes for high time resolution low-energy charged particle spectrometers
NASA Astrophysics Data System (ADS)
Saito, Yoshifumi; Yokota, Shoichiro; Asamura, Kazushi; Krieger, Amanda
2017-02-01
The time resolution of low-energy charged particle measurements is becoming higher and higher. In order to realize high time resolution measurements, a 1-D circular delay line anode has been developed as a high-speed microchannel plate (MCP) anode. The maximum count rate of the 1-D circular delay line anode is around 1 × 107/s/360°, which is much higher than the widely used resistive anode, whose maximum count rate is around 1 × 106/s/360°. In order to achieve much higher speeds, an MCP anode with application-specific integrated circuit (ASIC) has been developed. We have decided to adopt an anode configuration in which a discrete anode is formed on a ceramic substrate, and a bare ASIC chip is installed on the back of the ceramic. It has been found that the anode can detect at a high count rate of 2 × 108/s/360°. Developments in both delay line and discrete anodes, as well as readout electronics, will be reviewed.
Voysey, Merryn; Tavana, Rahele; Farooq, Yama; Heath, Paul T; Bonhoeffer, Jan; Snape, Matthew D
2015-12-16
Serious adverse events (SAEs) in clinical trials require reporting within 24h, including a judgment of whether the SAE was related to the investigational product(s). Such assessments are an important component of pharmacovigilance, however classification systems for assigning relatedness vary across study protocols. This on-line survey evaluated the consistency of SAE causality assessment among professionals with vaccine clinical trial experience. Members of the clinical advisory forum of experts (CAFÉ), a Brighton Collaboration online-forum, were emailed a survey containing SAEs from hypothetical vaccine trials which they were asked to classify. Participants were randomised to either two classification options (related/not related to study immunisation) or three options (possibly/probably/unrelated). The clinical scenarios, were (i) leukaemia diagnosed 5 months post-immunisation with a live RSV vaccine, (ii) juvenile idiopathic arthritis (JIA) 3 months post-immunisation with a group A streptococcal vaccine, (iii) developmental delay diagnosed at age 10 months after infant capsular group B meningococcal vaccine, (iv) developmental delay diagnosed at age 10 months after maternal immunisation with a group B streptococcal vaccine. There were 140 respondents (72 two options, 68 three options). Across all respondents, SAEs were considered related to study immunisation by 28% (leukaemia), 74% (JIA), 29% (developmental delay after infant immunisation) and 42% (developmental delay after maternal immunisation). Having only two options made respondents significantly less likely to classify the SAE as immunisation-related for two scenarios (JIA p=0.0075; and maternal immunisation p=0.045). Amongst study investigators (n=43) this phenomenon was observed for three of the four scenarios: (JIA p=0.0236; developmental delay following infant immunisation p=0.0266; and developmental delay after maternal immunisation p=0.0495). SAE causality assessment is inconsistent amongst study investigators and can be influenced by the classification systems available to them. There is a pressing need for SAE classification systems to be standardised across study protocols. Copyright © 2015 Elsevier Ltd. All rights reserved.
H0 from ten well-measured time delay lenses
NASA Astrophysics Data System (ADS)
Rathna Kumar, S.; Stalin, C. S.; Prabhu, T. P.
2015-08-01
In this work, we present a homogeneous curve-shifting analysis using the difference-smoothing technique of the publicly available light curves of 24 gravitationally lensed quasars, for which time delays have been reported in the literature. The uncertainty of each measured time delay was estimated using realistic simulated light curves. The recipe for generating such simulated light curves with known time delays in a plausible range around the measured time delay is introduced here. We identified 14 gravitationally lensed quasars that have light curves of sufficiently good quality to enable the measurement of at least one time delay between the images, adjacent to each other in terms of arrival-time order, to a precision of better than 20% (including systematic errors). We modeled the mass distribution of ten of those systems that have known lens redshifts, accurate astrometric data, and sufficiently simple mass distribution, using the publicly available PixeLens code to infer a value of H0 of 68.1 ± 5.9 km s-1 Mpc-1 (1σ uncertainty, 8.7% precision) for a spatially flat universe having Ωm = 0.3 and ΩΛ = 0.7. We note here that the lens modeling approach followed in this work is a relatively simple one and does not account for subtle systematics such as those resulting from line-of-sight effects and hence our H0 estimate should be considered as indicative.
NASA Astrophysics Data System (ADS)
Lin, Daw-Tung; Ligomenides, Panos A.; Dayhoff, Judith E.
1993-08-01
Inspired from the time delays that occur in neurobiological signal transmission, we describe an adaptive time delay neural network (ATNN) which is a powerful dynamic learning technique for spatiotemporal pattern transformation and temporal sequence identification. The dynamic properties of this network are formulated through the adaptation of time-delays and synapse weights, which are adjusted on-line based on gradient descent rules according to the evolution of observed inputs and outputs. We have applied the ATNN to examples that possess spatiotemporal complexity, with temporal sequences that are completed by the network. The ATNN is able to be applied to pattern completion. Simulation results show that the ATNN learns the topology of a circular and figure eight trajectories within 500 on-line training iterations, and reproduces the trajectory dynamically with very high accuracy. The ATNN was also trained to model the Fourier series expansion of the sum of different odd harmonics. The resulting network provides more flexibility and efficiency than the TDNN and allows the network to seek optimal values for time-delays as well as optimal synapse weights.
Three-dimensional ophthalmic optical coherence tomography with a refraction correction algorithm
NASA Astrophysics Data System (ADS)
Zawadzki, Robert J.; Leisser, Christoph; Leitgeb, Rainer; Pircher, Michael; Fercher, Adolf F.
2003-10-01
We built an optical coherence tomography (OCT) system with a rapid scanning optical delay (RSOD) line, which allows probing full axial eye length. The system produces Three-dimensional (3D) data sets that are used to generate 3D tomograms of the model eye. The raw tomographic data were processed by an algorithm, which is based on Snell"s law to correct the interface positions. The Zernike polynomials representation of the interfaces allows quantitative wave aberration measurements. 3D images of our results are presented to illustrate the capabilities of the system and the algorithm performance. The system allows us to measure intra-ocular distances.
Design of time interval generator based on hybrid counting method
NASA Astrophysics Data System (ADS)
Yao, Yuan; Wang, Zhaoqi; Lu, Houbing; Chen, Lian; Jin, Ge
2016-10-01
Time Interval Generators (TIGs) are frequently used for the characterizations or timing operations of instruments in particle physics experiments. Though some "off-the-shelf" TIGs can be employed, the necessity of a custom test system or control system makes the TIGs, being implemented in a programmable device desirable. Nowadays, the feasibility of using Field Programmable Gate Arrays (FPGAs) to implement particle physics instrumentation has been validated in the design of Time-to-Digital Converters (TDCs) for precise time measurement. The FPGA-TDC technique is based on the architectures of Tapped Delay Line (TDL), whose delay cells are down to few tens of picosecond. In this case, FPGA-based TIGs with high delay step are preferable allowing the implementation of customized particle physics instrumentations and other utilities on the same FPGA device. A hybrid counting method for designing TIGs with both high resolution and wide range is presented in this paper. The combination of two different counting methods realizing an integratable TIG is described in detail. A specially designed multiplexer for tap selection is emphatically introduced. The special structure of the multiplexer is devised for minimizing the different additional delays caused by the unpredictable routings from different taps to the output. A Kintex-7 FPGA is used for the hybrid counting-based implementation of a TIG, providing a resolution up to 11 ps and an interval range up to 8 s.
Ferroelectric liquid crystal device based photonic controllers for microwave antenna arrays
NASA Astrophysics Data System (ADS)
Madamopoulos, Nicholas
For the first time, this dissertation proposes, studies, analyzes, and experimentally demonstrates the use of ferroelectric liquid crystal (FLC) technology for wideband phased array control applications. FLC devices are used as polarization switches in photonic delay lines (PDLs) to control and process optical signals that drive the elements of a phased array antenna (PAA). The use of photonics for PAA control is, at present, a vital area of applied research. This dissertation work concludes with the demonstration of a multichannel 7-bit PDL system for a wideband PAA such as the Navy's advanced Aegis radar system. The unique system issues and problems to be examined and solved in this Ph.D. dissertation include the theoretical analysis and experimental demonstration of different PDL architectures covering a sub-nanosecond to several nanoseconds time delay range. New noise reduction/suppression schemes are proposed, studied and applied to give record level time delay system performance in terms of signal-to-leakage noise ratio, and switching speeds (e.g., 35 microseconds) required for fast radar scan. We show that the external modulation FO link gives more degrees of freedom to the system engineer, and we propose a novel synchronous RF signal calibration time delay control technique to obtain optimum dynamic range performance for our PDL. The use of low loss fibers for remoting of the photonic beamformer, as well as the losses associated with multiple fiber interconnects that limit the maximum number of array channels in the systems are studied. Different fiber optic coupling techniques are investigated for enhanced fiber coupling. Multimode fibers are used, for the first time, at the output plane of the PDL to obtain improved coupling efficiency. We demonstrate a low ~1.7 dB optical insertion loss/bit, which is very close to the desired insertion loss required for the Navy system. A novel approach for hardware reduction based on wavelength multiplexing is proposed, where the use of a combination of wavelength dependent and wavelength independent optical paths provides the required time delays. Finally, new switching fabric approaches are studied based on polarization selective holograms and their potential use for the implementation of PDLs is discussed.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Shilyagin, P A; Gelikonov, G V; Gelikonov, V M
2014-07-31
We have thoroughly investigated the method of simultaneous reception of spectral components with the achromatised quadrature phase shift between two portions of a reference wave, designed for the effective suppression of the 'mirror' artefact in the resulting image obtained by means of spectral domain optical coherence tomography (SD OCT). We have developed and experimentally tested a phase-shifting element consisting of a beam divider, which splits the reference optical beam into the two beams, and of delay lines being individual for each beam, which create a mutual phase difference of π/2 in the double pass of the reference beam. The phasemore » shift achromatism over a wide spectral range is achieved by using in the delay lines the individual elements with different dispersion characteristics. The ranges of admissible adjustment parameters of the achromatised delay line are estimated for exact and inexact conformity of the geometric characteristics of its components to those calculated. A possibility of simultaneous recording of the close-to-quadrature spectral components with a single linear photodetector element is experimentally confirmed. The suppression of the artefact mirror peak in the OCT-signal by an additional 9 dB relative to the level of its suppression is experimentally achieved when the air delay line is used. Two-dimensional images of the surface positioned at an angle to the axis of the probe beam are obtained with the correction of the 'mirror' artefact while maintaining the dynamic range of the image. (laser biophotonics)« less
The enigmatic WR46: A binary or a pulsator in disguise. II. The spectroscopy
NASA Astrophysics Data System (ADS)
Veen, P. M.; van Genderen, A. M.; Crowther, P. A.; van der Hucht, K. A.
2002-04-01
We present spectroscopic monitoring of the Wolf-Rayet (WR) star WR 46 between 1989 and 1998, which has been obtained simultaneously with multicolour photometry (Veen et al. \\cite{Veen02a}, Paper I). The spectroscopic monitoring data show that the radiative fluxes of the optical emission lines (O Vi 3811/34, O Vi 5290, N V 4944, N V 4604/20, He Ii 4686, He Ii 4859, He Ii 5411, He Ii 6560) vary in concert with the photometric single-wave (sw) frequency f_sw (Paper I), and also the difference of that period between 1989 and 1991. The line-flux variability does not provide obvious support for a short second period (Paper I). The radial-velocity variations show a remarkable behaviour: usually, they display a coherent single-wave on the time scale of the double-wave period, while during some nights the radial velocity appears surprisingly to stay constant (see also Marchenko et al. \\cite{Marchenko00}). These so-called stand-stills may be related to the observed time-delay effects. A time-delay effect manifests itself in several phenomena. Firstly, the line flux shows small, but persistent, time-delays for lines originating from lower optical depths, the outer-wind lines (N V 4604/20 and He Ii). Secondly, the radial-velocity variations display much larger time-delays than the line fluxes and their behaviour appears less consistent. Assuming that the double-wave period controls the radial velocity, the stand-still is observed to start when the radial motion is in anti-phase with the presumed orbital motion. Thirdly, the outer-wind lines are observed to enter a stand-still much later than the inner-wind lines. Fourthly, the radial-velocity variations of the peaks of the emission lines precede the radial-velocity variations of the wings of those lines. In addition to line-flux- and radial-velocity variability, the He Ii 4686 emission line shows pronounced line-profile changes on a time scale of hours. Our monitoring is not sufficient to study this in detail. Furthermore, we discern a flaring behaviour, i.e., an emission bump appeared on the blue wing of two He Ii-lines (around -1700 km s-1) lasting less than 5 min. Finally, the line fluxes follow the observed brightenings, also on a time scale of years. We conclude that the short-term cyclic variability confirms the WR nature as established from the WR standard model analysis by Crowther et al. (\\cite{Crowther95}; hereafter referred to as CSH). The various time-delay effects are consistent with the formation of the spectrum in a stratified stellar wind. The outer layers trail the inner ones. The variability is inconsistent with the formation of the spectrum in a stellar disc as proposed by Niemela et al. (\\cite{Niemela95}) and Steiner & Diaz (\\cite{Steiner98}). The long-term cyclic variability of the brightness and line fluxes is related to an increase of the mass-loss-rate, and, possibly, to the period changes. The interpretation of the nature of the variability is deferred to Veen et al. (\\cite{Veen02b}, Paper III). Based on observations collected at the European Southern Observatory (ESO), La Silla, Chile.
Time Domain and Frequency Domain Deterministic Channel Modeling for Tunnel/Mining Environments.
Zhou, Chenming; Jacksha, Ronald; Yan, Lincan; Reyes, Miguel; Kovalchik, Peter
2017-01-01
Understanding wireless channels in complex mining environments is critical for designing optimized wireless systems operated in these environments. In this paper, we propose two physics-based, deterministic ultra-wideband (UWB) channel models for characterizing wireless channels in mining/tunnel environments - one in the time domain and the other in the frequency domain. For the time domain model, a general Channel Impulse Response (CIR) is derived and the result is expressed in the classic UWB tapped delay line model. The derived time domain channel model takes into account major propagation controlling factors including tunnel or entry dimensions, frequency, polarization, electrical properties of the four tunnel walls, and transmitter and receiver locations. For the frequency domain model, a complex channel transfer function is derived analytically. Based on the proposed physics-based deterministic channel models, channel parameters such as delay spread, multipath component number, and angular spread are analyzed. It is found that, despite the presence of heavy multipath, both channel delay spread and angular spread for tunnel environments are relatively smaller compared to that of typical indoor environments. The results and findings in this paper have application in the design and deployment of wireless systems in underground mining environments.
Time Domain and Frequency Domain Deterministic Channel Modeling for Tunnel/Mining Environments
Zhou, Chenming; Jacksha, Ronald; Yan, Lincan; Reyes, Miguel; Kovalchik, Peter
2018-01-01
Understanding wireless channels in complex mining environments is critical for designing optimized wireless systems operated in these environments. In this paper, we propose two physics-based, deterministic ultra-wideband (UWB) channel models for characterizing wireless channels in mining/tunnel environments — one in the time domain and the other in the frequency domain. For the time domain model, a general Channel Impulse Response (CIR) is derived and the result is expressed in the classic UWB tapped delay line model. The derived time domain channel model takes into account major propagation controlling factors including tunnel or entry dimensions, frequency, polarization, electrical properties of the four tunnel walls, and transmitter and receiver locations. For the frequency domain model, a complex channel transfer function is derived analytically. Based on the proposed physics-based deterministic channel models, channel parameters such as delay spread, multipath component number, and angular spread are analyzed. It is found that, despite the presence of heavy multipath, both channel delay spread and angular spread for tunnel environments are relatively smaller compared to that of typical indoor environments. The results and findings in this paper have application in the design and deployment of wireless systems in underground mining environments.† PMID:29457801
Associations between immunological function and memory recall in healthy adults.
Wang, Grace Y; Taylor, Tamasin; Sumich, Alexander; Merien, Fabrice; Borotkanics, Robert; Wrapson, Wendy; Krägeloh, Chris; Siegert, Richard J
2017-12-01
Studies in clinical and aging populations support associations between immunological function, cognition and mood, although these are not always in line with animal models. Moreover, very little is known about the relationship between immunological measures and cognition in healthy young adults. The present study tested associations between the state of immune system and memory recall in a group of relatively healthy adults. Immediate and delayed memory recall was assessed in 30 participants using the computerised cognitive battery. CD4, CD8 and CD69 subpopulations of lymphocytes, Interleukin-6 (IL-6) and cortisol were assessed with blood assays. Correlation analysis showed significant negative relationships between CD4 and the short and long delay memory measures. IL-6 showed a significant positive correlation with long-delay recall. Generalized linear models found associations between differences in all recall challenges and CD4. A multivariate generalized linear model including CD4 and IL-6 exhibited a stronger association. Results highlight the interactions between CD4 and IL-6 in relation to memory function. Further study is necessary to determine the underlying mechanisms of the associations between the state of immune system and cognitive performance. Copyright © 2017 Elsevier Inc. All rights reserved.
NASA Astrophysics Data System (ADS)
Rao, Hanumantha; Kumar, Vasanta; Srinivasa Rao, T.; Srinivasa Kumar, B.
2018-04-01
In this paper, we examine a two-stage queueing system where the arrivals are Poisson with rate depends on the condition of the server to be specific: vacation, pre-service, operational or breakdown state. The service station is liable to breakdowns and deferral in repair because of non-accessibility of the repair facility. The service is in two basic stages, the first being bulk service to every one of the customers holding up on the line and the second stage is individual to each of them. The server works under N-policy. The server needs preliminary time (startup time) to begin batch service after a vacation period. Startup times, uninterrupted service times, the length of each vacation period, delay times and service times follows an exponential distribution. The closed form of expressions for the mean system size at different conditions of the server is determined. Numerical investigations are directed to concentrate the impact of the system parameters on the ideal limit N and the minimum base expected unit cost.
NASA Astrophysics Data System (ADS)
2001-01-01
Last year saw very good progress at ESO's Paranal Observatory , the site of the Very Large Telescope (VLT). The third and fourth 8.2-m Unit Telescopes, MELIPAL and YEPUN had "First Light" (cf. PR 01/00 and PR 18/00 ), while the first two, ANTU and KUEYEN , were busy collecting first-class data for hundreds of astronomers. Meanwhile, work continued towards the next phase of the VLT project, the combination of the telescopes into the VLT Interferometer. The test instrument, VINCI (cf. PR 22/00 ) is now being installed in the VLTI Laboratory at the centre of the observing platform on the top of Paranal. Below is a new collection of video sequences and photos that illustrate the latest developments at the Paranal Observatory. The were obtained by the EPR Video Team in December 2000. The photos are available in different formats, including "high-resolution" that is suitable for reproduction purposes. A related ESO Video News Reel for professional broadcasters will soon become available and will be announced via the usual channels. Overview Paranal Observatory (Dec. 2000) Video Clip 02a/01 [MPEG - 4.5Mb] ESO PR Video Clip 02a/01 "Paranal Observatory (December 2000)" (4875 frames/3:15 min) [MPEG Video+Audio; 160x120 pix; 4.5Mb] [MPEG Video+Audio; 320x240 pix; 13.5 Mb] [RealMedia; streaming; 34kps] [RealMedia; streaming; 200kps] ESO Video Clip 02a/01 shows some of the construction activities at the Paranal Observatory in December 2000, beginning with a general view of the site. Then follow views of the Residencia , a building that has been designed by Architects Auer and Weber in Munich - it integrates very well into the desert, creating a welcome recreational site for staff and visitors in this harsh environment. The next scenes focus on the "stations" for the auxiliary telescopes for the VLTI and the installation of two delay lines in the 140-m long underground tunnel. The following part of the video clip shows the start-up of the excavation work for the 2.6-m VLT Survey Telescope (VST) as well as the location known as the "NTT Peak", now under consideration for the installation of the 4-m VISTA telescope. The last images are from to the second 8.2-m Unit Telescope, KUEYEN, that has been in full use by the astronomers with the UVES and FORS2 instruments since April 2000. ESO PR Photo 04a/01 ESO PR Photo 04a/01 [Preview - JPEG: 466 x 400 pix - 58k] [Normal - JPEG: 931 x 800 pix - 688k] [Hires - JPEG: 3000 x 2577 pix - 7.6M] Caption : PR Photo 04a/01 shows an afternoon view from the Paranal summit towards East, with the Base Camp and the new Residencia on the slope to the right, above the valley in the shadow of the mountain. ESO PR Photo 04b/01 ESO PR Photo 04b/01 [Preview - JPEG: 791 x 400 pix - 89k] [Normal - JPEG: 1582 x 800 pix - 1.1Mk] [Hires - JPEG: 3000 x 1517 pix - 3.6M] PR Photo 04b/01 shows the ramp leading to the main entrance to the partly subterranean Residencia , with the steel skeleton for the dome over the central area in place. ESO PR Photo 04c/01 ESO PR Photo 04c/01 [Preview - JPEG: 498 x 400 pix - 65k] [Normal - JPEG: 995 x 800 pix - 640k] [Hires - JPEG: 3000 x 2411 pix - 6.6M] PR Photo 04c/01 is an indoor view of the reception hall under the dome, looking towards the main entrance. ESO PR Photo 04d/01 ESO PR Photo 04d/01 [Preview - JPEG: 472 x 400 pix - 61k] [Normal - JPEG: 944 x 800 pix - 632k] [Hires - JPEG: 3000 x 2543 pix - 5.8M] PR Photo 04d/01 shows the ramps from the reception area towards the rooms. The VLT Interferometer The Delay Lines consitute a most important element of the VLT Interferometer , cf. PR Photos 26a-e/00. At this moment, two Delay Lines are operational on site. A third system will be integrated early this year. The VLTI Delay Line is located in an underground tunnel that is 168 metres long and 8 metres wide. This configuration has been designed to accommodate up to eight Delay Lines, including their transfer optics in an ideal environment: stable temperature, high degree of cleanliness, low levels of straylight, low air turbulence. The positions of the Delay Line carriages are computed to adjust the Optical Path Lengths requested for the fringe pattern observation. The positions are controlled in real time by a laser metrology system, specially developed for this purpose. The position precision is about 20 nm (1 nm = 10 -9 m, or 1 millionth of a millimetre) over a distance of 120 metres. The maximum velocity is 0.50 m/s in position mode and maximum 0.05 m/s in operation. The system is designed for 25 year of operation and to survive earthquake up to 8.6 magnitude on the Richter scale. The VLTI Delay Line is a three-year project, carried out by ESO in collaboration with Dutch Space Holdings (formerly Fokker Space) and TPD-TNO . VLTI Delay Lines (December 2000) - ESO PR Video Clip 02b/01 [MPEG - 3.6Mb] ESO PR Video Clip 02b/01 "VLTI Delay Lines (December 2000)" (2000 frames/1:20 min) [MPEG Video+Audio; 160x120 pix; 3.6Mb] [MPEG Video+Audio; 320x240 pix; 13.7 Mb] [RealMedia; streaming; 34kps] [RealMedia; streaming; 200kps] ESO Video Clip 02b/00 shows the Delay Lines of the VLT Interferometer facility at Paranal during tests. One of the carriages is moving on 66-metre long rectified rails, driven by a linear motor. The carriage is equipped with three wheels in order to preserve high guidance accuracy. Another important element is the Cat's Eye that reflects the light from the telescope to the VLT instrumentation. This optical system is made of aluminium (including the mirrors) to avoid thermo-mechanical problems. ESO PR Photo 04e/01 ESO PR Photo 04e/01 [Preview - JPEG: 400 x 402 pix - 62k] [Normal - JPEG: 800 x 804 pix - 544k] [Hires - JPEG: 3000 x 3016 pix - 6.2M] Caption : PR Photo 04e/01 shows one of the 30 "stations" for the movable 1.8-m Auxiliary Telescopes. When one of these telescopes is positioned ("parked") on top of it, The light will be guided through the hole towards the Interferometric Tunnel and the Delay Lines. ESO PR Photo 04f/01 ESO PR Photo 04f/01 [Preview - JPEG: 568 x 400 pix - 96k] [Normal - JPEG: 1136 x 800 pix - 840k] [Hires - JPEG: 3000 x 2112 pix - 4.6M] PR Photo 04f/01 shows a general view of the Interferometric Tunnel and the Delay Lines. ESO PR Photo 04g/01 ESO PR Photo 04g/01 [Preview - JPEG: 406 x 400 pix - 62k] [Normal - JPEG: 812 x 800 pix - 448k] [Hires - JPEG: 3000 x 2956 pix - 5.5M] PR Photo 04g/01 shows one of the Delay Line carriages in parking position. The "NTT Peak" The "NTT Peak" is a mountain top located about 2 km to the north of Paranal. It received this name when ESO considered to move the 3.58-m New Technology Telescope from La Silla to this peak. The possibility of installing the 4-m VISTA telescope (cf. PR 03/00 ) on this peak is now being discussed. ESO PR Photo 04h/01 ESO PR Photo 04h/01 [Preview - JPEG: 630 x 400 pix - 89k] [Normal - JPEG: 1259 x 800 pix - 1.1M] [Hires - JPEG: 3000 x 1907 pix - 5.2M] PR Photo 04h/01 shows the view from the "NTT Peak" towards south, vith the Paranal mountain and the VLT enclosures in the background. ESO PR Photo 04i/01 ESO PR Photo 04i/01 [Preview - JPEG: 516 x 400 pix - 50k] [Normal - JPEG: 1031 x 800 pix - 664k] [Hires - JPEG: 3000 x 2328 pix - 6.0M] PR Photo 04i/01 is a view towards the "NTT Peak" from the top of the Paranal mountain. The access road and the concrete pillar that was used to support a site testing telescope at the top of this peak are seen This is the caption to ESO PR Photos 04a-1/01 and PR Video Clips 02a-b/01 . They may be reproduced, if credit is given to the European Southern Observatory. The ESO PR Video Clips service to visitors to the ESO website provides "animated" illustrations of the ongoing work and events at the European Southern Observatory. The most recent clip was: ESO PR Video Clip 01/01 about the Physics On Stage Festival (11 January 2001) . Information is also available on the web about other ESO videos.
NASA Astrophysics Data System (ADS)
Epstein, A.; Briquet-Laugier, F.; Sheldon, S.; Boulin, C.
2000-04-01
Most of the X-ray multi-wire gas detectors used at the EMBL Hamburg outstation for time-resolved studies of biological samples are readout, using the delay line method. The main disadvantage of such readout systems is their event rate limitation introduced by the delay line and the required time to digital conversion step. They also lack the possibility to deal with multiple events. To overcome these limitations, a new approach for the complete readout system was introduced. The new linear detection system is based on the wire per wire approach where each individual wire is associated to preamplifier/discriminator/counter electronics channel. High-density, front-end electronics were designed around a fast current sensitive preamplifier. An eight-channel board was designed to include the preamplifiers-discriminators and the differential ECL drivers output stages. The detector front-end consists of 25 boards directly mounted inside the detector assembly. To achieve a time framing resolution as short as 10 /spl mu/s, very fast histogramming is required. The only way to implement this for a high number of channels (200 in our case) is by using a distributed system. The digital part of the system consists of a crate controller, up to 16 acquisition boards (capable of handling fast histogramming for up to 32-channels each) and an optical-link board (based on the Cypress "Hot-Link" chip set). Both the crate controller and the acquisition boards are based on a standard RISC microcontroller (IDT R3081) plug-in board. At present, a dedicated CAMAC module which we developed is used to interface the digital front-end acquisition crate to the host via the optical link.
NASA Technical Reports Server (NTRS)
Iannicca, Dennis; Hylton, Alan; Ishac, Joseph
2012-01-01
Delay-Tolerant Networking (DTN) is an active area of research in the space communications community. DTN uses a standard layered approach with the Bundle Protocol operating on top of transport layer protocols known as convergence layers that actually transmit the data between nodes. Several different common transport layer protocols have been implemented as convergence layers in DTN implementations including User Datagram Protocol (UDP), Transmission Control Protocol (TCP), and Licklider Transmission Protocol (LTP). The purpose of this paper is to evaluate several stand-alone implementations of negative-acknowledgment based transport layer protocols to determine how they perform in a variety of different link conditions. The transport protocols chosen for this evaluation include Consultative Committee for Space Data Systems (CCSDS) File Delivery Protocol (CFDP), Licklider Transmission Protocol (LTP), NACK-Oriented Reliable Multicast (NORM), and Saratoga. The test parameters that the protocols were subjected to are characteristic of common communications links ranging from terrestrial to cis-lunar and apply different levels of delay, line rate, and error.
NASA Astrophysics Data System (ADS)
Rusu, Cristian E.; Fassnacht, Christopher D.; Sluse, Dominique; Hilbert, Stefan; Wong, Kenneth C.; Huang, Kuang-Han; Suyu, Sherry H.; Collett, Thomas E.; Marshall, Philip J.; Treu, Tommaso; Koopmans, Leon V. E.
2017-06-01
Based on spectroscopy and multiband wide-field observations of the gravitationally lensed quasar HE 0435-1223, we determine the probability distribution function of the external convergence κext for this system. We measure the under/overdensity of the line of sight towards the lens system and compare it to the average line of sight throughout the Universe, determined by using the CFHTLenS (The Canada France Hawaii Lensing Survey) as a control field. Aiming to constrain κext as tightly as possible, we determine under/overdensities using various combinations of relevant informative weighting schemes for the galaxy counts, such as projected distance to the lens, redshift and stellar mass. We then convert the measured under/overdensities into a κext distribution, using ray-tracing through the Millennium Simulation. We explore several limiting magnitudes and apertures, and account for systematic and statistical uncertainties relevant to the quality of the observational data, which we further test through simulations. Our most robust estimate of κext has a median value κ^med_ext = 0.004 and a standard deviation σκ = 0.025. The measured σκ corresponds to 2.5 per cent relative uncertainty on the time delay distance, and hence the Hubble constant H0 inferred from this system. The median κ^med_ext value varies by ˜0.005 with the adopted aperture radius, limiting magnitude and weighting scheme, as long as the latter incorporates galaxy number counts, the projected distance to the main lens and a prior on the external shear obtained from mass modelling. This corresponds to just ˜0.5 per cent systematic impact on H0. The availability of a well-constrained κext makes HE 0435-1223 a valuable system for measuring cosmological parameters using strong gravitational lens time delays.
14 CFR 1214.805 - Unforeseen customer delay.
Code of Federal Regulations, 2013 CFR
2013-01-01
... problem pose a threat of delay to the Shuttle launch schedule or critical off-line activities, NASA shall... availability of facilities, equipment, and personnel. In requesting NASA to make such special efforts, the customer shall agree to reimburse NASA the estimated additional cost incurred. ...
14 CFR 1214.805 - Unforeseen customer delay.
Code of Federal Regulations, 2011 CFR
2011-01-01
... problem pose a threat of delay to the Shuttle launch schedule or critical off-line activities, NASA shall... availability of facilities, equipment, and personnel. In requesting NASA to make such special efforts, the customer shall agree to reimburse NASA the estimated additional cost incurred. ...
14 CFR 1214.805 - Unforeseen customer delay.
Code of Federal Regulations, 2012 CFR
2012-01-01
... problem pose a threat of delay to the Shuttle launch schedule or critical off-line activities, NASA shall... availability of facilities, equipment, and personnel. In requesting NASA to make such special efforts, the customer shall agree to reimburse NASA the estimated additional cost incurred. ...
Qin, Heng; Zuo, Yong; Zhang, Dong; Li, Yinghui; Wu, Jian
2017-03-06
Through slight modification on typical photon multiplier tube (PMT) receiver output statistics, a generalized received response model considering both scattered propagation and random detection is presented to investigate the impact of inter-symbol interference (ISI) on link data rate of short-range non-line-of-sight (NLOS) ultraviolet communication. Good agreement with the experimental results by numerical simulation is shown. Based on the received response characteristics, a heuristic check matrix construction algorithm of low-density-parity-check (LDPC) code is further proposed to approach the data rate bound derived in a delayed sampling (DS) binary pulse position modulation (PPM) system. Compared to conventional LDPC coding methods, better bit error ratio (BER) below 1E-05 is achieved for short-range NLOS UVC systems operating at data rate of 2Mbps.
A Reverberation-based Black Hole Mass for MCG-06-30-15
NASA Astrophysics Data System (ADS)
Bentz, Misty C.; Cackett, Edward M.; Crenshaw, D. Michael; Horne, Keith; Street, Rachel; Ou-Yang, Benjamin
2016-10-01
We present the results of a reverberation campaign targeting MGC-06-30-15. Spectrophotometric monitoring and broad-band photometric monitoring over the course of four months in spring 2012 allowed a determination of a time delay in the broad Hβ emission line of τ = 5.3 ± 1.8 days in the rest frame of the active galactic nucleus (AGN). Combined with the width of the variable portion of the emission line, we determine a black hole mass of M BH = (1.6 ± 0.4) × 106 M ⊙. Both the Hβ time delay and the black hole mass are in good agreement with expectations from the R BLR-L and M BH-σ ⋆ relationships for other reverberation-mapped AGNs. The Hβ time delay is also in good agreement with the relationship between Hβ and broad-band near-IR delays, in which the effective size of the broad-line region is ˜4-5 times smaller than the inner edge of the dust torus. Additionally, the reverberation-based mass is in good agreement with estimates from the scaling relationship of the break in the X-ray power spectral density, and with constraints based on stellar kinematics derived from integral field spectroscopy of the inner ˜0.5 kpc of the galaxy.
Relationships between processing delay and microbial load of broiler neck skin samples.
Lucianez, A; Holmes, M A; Tucker, A W
2010-01-01
The measurable microbial load on poultry carcasses during processing is determined by a number of factors including farm or origin, processing hygiene, and external temperature. This study investigated associations between carcass microbial load and progressive delays to processing. A total of 30 carcasses were delayed immediately after defeathering and before evisceration in a commercial abattoir in groups of five, and were held at ambient temperature for 1, 2, 3, 4, 6, and 8 h. Delayed carcasses were reintroduced to the processing line, and quantitative assessment of total viable count, coliforms, Staphylococcus aureus, and Pseudomonas spp. was undertaken on neck skin flap samples collected after carcass chilling and then pooled for each group. Sampling was repeated on 5 separate days, and the data were combined. Significant increases in total viable count (P = 0.001) and coliforms (P = 0.004), but not for S. aureus or Pseudomonas loads, were observed across the 8-h period of delay. In line with previous studies, there was significant variation in microbiological data according to sampling day. In conclusion, there is a significant and measurable decline in microbiological status of uneviscerated but defeathered poultry carcasses after an 8-h delay, but the variability of sampling results, reflecting the wide range of factors that impact microbial load, means that it is not possible to determine maximum or minimum acceptable periods of processing delay based on this criterion alone.
MOEMS optical delay line for optical coherence tomography
NASA Astrophysics Data System (ADS)
Choudhary, Om P.; Chouksey, S.; Sen, P. K.; Sen, P.; Solanki, J.; Andrews, J. T.
2014-09-01
Micro-Opto-Electro-Mechanical optical coherence tomography, a lab-on-chip for biomedical applications is designed, studied, fabricated and characterized. To fabricate the device standard PolyMUMPS processes is adopted. We report the utilization of electro-optic modulator for a fast scanning optical delay line for time domain optical coherence tomography. Design optimization are performed using Tanner EDA while simulations are performed using COMSOL. The paper summarizes various results and fabrication methodology adopted. The success of the device promises a future hand-held or endoscopic optical coherence tomography for biomedical applications.
14 CFR § 1214.805 - Unforeseen customer delay.
Code of Federal Regulations, 2014 CFR
2014-01-01
... problem pose a threat of delay to the Shuttle launch schedule or critical off-line activities, NASA shall... availability of facilities, equipment, and personnel. In requesting NASA to make such special efforts, the customer shall agree to reimburse NASA the estimated additional cost incurred. ...
A Novel 2-D Programmable Photonic Time Delay Device for MM-Wave Signal Processing Applications
NASA Technical Reports Server (NTRS)
Yao, X.; Maleki, L.
1994-01-01
We describe a novel programmable photonic true time delay device that has the properties of low loss, inherent two dimensionality with a packing density exceeding 25 lines/cm super 2, virtually infinite bandwidth, and is easy to manufacture.
NASA Astrophysics Data System (ADS)
Huang, Jinhui; Liu, Wenxiang; Su, Yingxue; Wang, Feixue
2018-02-01
Space networks, in which connectivity is deterministic and intermittent, can be modeled by delay/disruption tolerant networks. In space delay/disruption tolerant networks, a packet is usually transmitted from the source node to the destination node indirectly via a series of relay nodes. If anyone of the nodes in the path becomes congested, the packet will be dropped due to buffer overflow. One of the main reasons behind congestion is the unbalanced network traffic distribution. We propose a load balancing strategy which takes the congestion status of both the local node and relay nodes into account. The congestion status, together with the end-to-end delay, is used in the routing selection. A lookup-table enhancement is also proposed. The off-line computation and the on-line adjustment are combined together to make a more precise estimate of the end-to-end delay while at the same time reducing the onboard computation. Simulation results show that the proposed strategy helps to distribute network traffic more evenly and therefore reduces the packet drop ratio. In addition, the average delay is also decreased in most cases. The lookup-table enhancement provides a compromise between the need for better communication performance and the desire for less onboard computation.
MicroChemLab, A Novel Approach for Handheld Chemical Sensing
NASA Astrophysics Data System (ADS)
Lewis, Patrick
2003-03-01
In 1996, Sandia National Laboratories began development of a chemical sensing platform based on microfabricated components. The goal of the project was to develop a handheld system for the detection of chemical warfare (CW) agent vapors in air. The components developed for this project are analogous to devices used in analytical laboratories. The benefit of microfabrication is that the resulting components are small and require little power to operate. The key elements of MicroChemLab are a sample collector - preconcentrator, a GC column and a surface acoustic wave (SAW) array detector. The preconcentrator is a thermally isolated silicon nitride membrane with a resistive heater patterned on one side and a sorptive sol gel film deposited on the other. Since the membrane has a very small mass, the resistive heater can ballistically elevate the temperature of the sorptive film to 200° C in approximately 10 ms. The sol gel film collects target compounds efficiently, but rejects volatile industrial solvents like alcohols, ketones, etc. The GC column is a one-meter high aspect ratio spiral channel etched in silicon with an anodically bonded pyrex lid completing the channel. A heater patterned on the silicon allows the column to be temperature ramped. Analytes injected from the preconcentrator are separated in this stage. The SAW array detector contains 3 delay lines used for sensing and 1 reference delay line. Each delay line is driven by an application specific integrated circuit (ASIC) at 500 MHz. Instead of counting frequency, additional ASICs incorporate a phase comparator that delivers a DC signal proportional to the amount of phase change. The three sensing elements of the detector provide a pattern that is indicative of the class of compound detected i.e. nerve agents or blister agents. Combined, these components provide a selective and sensitive handheld solution for the detection of chemical warfare agents. We will present lab data showing the performance of individual components and field data demonstrating the performance of this system. Sandia is a multiprogram laboratory operated by Sandia Corporation, a Lockheed Martin Company, for the United States Department of Energy under Contract DE-AC04-94AL85000.
NASA Astrophysics Data System (ADS)
Ranjan, Suman; Mandal, Sanjoy
2017-12-01
Modeling of triple asymmetrical optical micro ring resonator (TAOMRR) in z-domain with 2 × 2 input-output system with detailed design of its waveguide configuration using finite-difference time-domain (FDTD) method is presented. Transfer function in z-domain using delay-line signal processing technique of the proposed TAOMRR is determined for different input and output ports. The frequency response analysis is carried out using MATLAB software. Group delay and dispersion characteristics are also determined in MATLAB. The electric field analysis is done using FDTD. The method proposes a new methodology to design and draw multiple configurations of coupled ring resonators having multiple in and out ports. Various important parameters such as coupling coefficients and FSR are also determined.
NASA Astrophysics Data System (ADS)
Ranjan, Suman; Mandal, Sanjoy
2018-02-01
Modeling of triple asymmetrical optical micro ring resonator (TAOMRR) in z-domain with 2 × 2 input-output system with detailed design of its waveguide configuration using finite-difference time-domain (FDTD) method is presented. Transfer function in z-domain using delay-line signal processing technique of the proposed TAOMRR is determined for different input and output ports. The frequency response analysis is carried out using MATLAB software. Group delay and dispersion characteristics are also determined in MATLAB. The electric field analysis is done using FDTD. The method proposes a new methodology to design and draw multiple configurations of coupled ring resonators having multiple in and out ports. Various important parameters such as coupling coefficients and FSR are also determined.
Fazal, Irfan; Yilmaz, Omer; Nuccio, Scott; Zhang, Bo; Willner, Alan E; Langrock, Carsten; Fejer, Martin M
2007-08-20
10 Gb/s non-return-to-zero (NRZ) on-off keyed (OOK) optical data packets are synchronized and time-multiplexed using a 26-ns tunable all-optical delay line. The delay element is based on wavelength conversion in periodically poled lithium niobate (PPLN) waveguides, inter-channel chromatic dispersion in dispersion compensating fiber (DCF) and intra-channel dispersion compensation with a chirped fiber Bragg grating (FBG). Delay reconfiguration time is measured to be less than 300 ps.
Combinational logic for generating gate drive signals for phase control rectifiers
NASA Technical Reports Server (NTRS)
Dolland, C. R.; Trimble, D. W. (Inventor)
1982-01-01
Control signals for phase-delay rectifiers, which require a variable firing angle that ranges from 0 deg to 180 deg, are derived from line-to-line 3-phase signals and both positive and negative firing angle control signals which are generated by comparing current command and actual current. Line-to-line phases are transformed into line-to-neutral phases and integrated to produce 90 deg phase delayed signals that are inverted to produce three cosine signals, such that for each its maximum occurs at the intersection of positive half cycles of the other two phases which are inputs to other inverters. At the same time, both positive and negative (inverted) phase sync signals are generated for each phase by comparing each with the next and producing a square wave when it is greater. Ramp, sync and firing angle controls signals are than used in combinational logic to generate the gate firing control signals SCR gate drives which fire SCR devices in a bridge circuit.
High-temperature superconductivity for avionic electronic warfare and radar systems
NASA Astrophysics Data System (ADS)
Ryan, Paul A.
1994-01-01
The electronic warfare (EW) and radar communities expect to be major beneficiaries of the performance advantages high-temperature superconductivity (HTS) has to offer over conventional technology. Near term upgrades to system hardware can be envisioned using extremely small, high Q, microwave filters and resonators; compact, wideband, low loss, microwave delay and transmission lines; as well as, wideband, low loss, monolithic microwave integrated circuit phase shifters. The most dramatic impact will be in the far term, using HTS to develop new, real time threat identification and response strategy receiver/processing systems designed to utilize the unique high frequency properties of microwave and ultimately digital HTS.
Integrating free-space optical communication links with existing WiFi (WiFO) network
NASA Astrophysics Data System (ADS)
Liverman, S.; Wang, Q.; Chu, Y.; Duong, T.; Nguyen-Huu, D.; Wang, S.; Nguyen, T.; Wang, A. X.
2016-02-01
Recently, free-space optical (FSO) systems have generated great interest due to their large bandwidth potential and a line-of-sight physical layer of protection. In this paper, we propose WiFO, a novel hybrid system, FSO downlink and WiFi uplink, which will integrate currently available WiFi infrastructure with inexpensive infrared light emitting diodes. This system takes full advantage of the mobility inherent in WiFi networks while increasing the downlink bandwidth available to each end user. We report the results of our preliminary investigation that show the capabilities of our prototype design in terms of bandwidth, bit error rates, delays and transmission distances.
Coherent optical modulation for antenna remoting
NASA Technical Reports Server (NTRS)
Fitzmartin, D. J.; Gels, R. G.; Balboni, E. J.
1991-01-01
A coherent fiber optic link employing wideband frequency modulation (FM) of the optical carrier is used to transfer radio frequency (RF) or microwave signals. This system is used to link a remotely located antenna to a conveniently located electronics processing site. The advantages of coherent analog fiber optic systems over non-coherent intensity modulated fiber optic analog transmission systems are described. An optical FM link employing an indirect transmitter to frequency modulate the optical carrier and a microwave delay line discriminator receiver is described. Measured performance data for a video signal centered at 60 MHz is presented showing the use of wideband FM in the link.
Delayed fission of atomic nuclei (To the 50th anniversary of the discovery)
NASA Astrophysics Data System (ADS)
Skobelev, N. K.
2017-09-01
The history of the discovery of delayed nuclear fission is presented, and the retrospective of investigations into this phenomenon that were performed at various research centers worldwide is outlined. The results obtained by measuring basic delayed-fission features, including the fission probability, the total kinetic energy of fission fragments, and their mass distributions, are analyzed. Recommendations concerning further studies in various regions of nuclear map with the aim of searches for and investigation of atomic nuclei undergoing delayed fission are given. Lines of further research into features of delayed fission with the aim of solving current problems of fission physics are discussed.
NASA Astrophysics Data System (ADS)
Grasso, Rosaria; Cammarata, Francesco Paolo; Minafra, Luigi; Marchese, Valentina; Russo, Giorgio; Manti, Lorenzo; Musumeci, Francesco; Scordino, Agata
2017-07-01
In the framework of the research project ETHICS "Pre-clinical experimental and theoretical studies to improve treatment and protection by charged particles" funded by the National Nuclear Physics Institute, Italy, we studied the phenomenon called delayed luminescence emitted by non-tumorigenic breast epithelial MCF10A cell line after proton irradiation at different doses (0.5, 2, 6, 9 Gy). The aim is to found possible correlations between delayed luminescence and in vitro damaging induced by ion irradiation. The first results of this research show that the delayed luminescence kinetics is proton dose dependent. An interesting correlation between delayed luminescence and clonogenic potential was observed.
NASA Technical Reports Server (NTRS)
Dhabal, Arnab; Rinehart, Stephen A.; Rizzo, Maxime J.; Mundy, Lee; Fixsen, Dale; Sampler, Henry; Mentzell, Eric; Veach, Todd; Silverberg, Robert F.; Furst, Stephen;
2016-01-01
We present the optics of Balloon Experimental Twin Telescope for Infrared Interferometry (BETTII) as it gets ready for launch. BETTII is an 8-meter baseline far-infrared (30-90 microns) interferometer mission with capabilities of spatially resolved spectroscopy aimed at studying star formation and galaxy evolution. The instrument collects light from its two arms, makes them interfere, divides them into two science channels (30-50 microns and 60-90 microns), and focuses them onto the detectors. It also separates out the NIR light (1-2.5 microns) and uses it for tip-tilt corrections of the telescope pointing. Currently, all the optical elements have been fabricated, heat treated, coated appropriately and are mounted on their respective assemblies. We are presenting the optical design challenges for such a balloon borne spatio-spectral interferometer, and discuss how they have been mitigated. The warm and cold delay lines are an important part of this optics train. The warm delay line corrects for path length differences between the left and the right arm due to balloon pendulation, while the cold delay line is aimed at introducing a systematic path length difference, thereby generating our interferograms from where we can derive information about the spectra. The details of their design and the results of the testing of these opto-mechanical parts are also discussed. The sensitivities of different optical elements on the interferograms produced have been determined with the help of simulations using FRED software package. Accordingly, an alignment plan is drawn up which makes use of a laser tracker, a CMM, theodolites and a LUPI interferometer.
Thomson, G.P.; Blackman, M.
1961-07-25
BS>A device is descrined for producing nuclear fusion reactions by additional acceleration of a hydrogen isotope plasma formed and initially accelerated by a collapsing magnetic field. The plasma is enclosed in a toroidal cavity within a vessel composed of a plurality of insulated coaxial segments. The added acceleration is caused by providing progressing potentials to the insulated segments acting as electrodes by means of a segmented delay transmission line coupled to the electrode segments and excited by a two phase alternating current supply.
Delayed luminescence to monitor programmed cell death induced by berberine on thyroid cancer cells
NASA Astrophysics Data System (ADS)
Scordino, Agata; Campisi, Agata; Grasso, Rosaria; Bonfanti, Roberta; Gulino, Marisa; Iauk, Liliana; Parenti, Rosalba; Musumeci, Francesco
2014-11-01
Correlation between apoptosis and UVA-induced ultraweak photon emission delayed luminescence (DL) from tumor thyroid cell lines was investigated. In particular, the effects of berberine, an alkaloid that has been reported to have anticancer activities, on two cancer cell lines were studied. The FTC-133 and 8305C cell lines, as representative of follicular and anaplastic thyroid human cancer, respectively, were chosen. The results show that berberine is able to arrest cell cycle and activate apoptotic pathway as shown in both cell lines by deoxyribonucleic acid fragmentation, caspase-3 cleavage, p53 and p27 protein overexpression. In parallel, changes in DL spectral components after berberine treatment support the hypothesis that DL from human cells originates mainly from mitochondria, since berberine acts especially at the mitochondrial level. The decrease of DL blue component for both cell lines could be related to the decrease of intra-mitochondrial nicotinamide adenine dinucleotide and may be a hallmark of induced apoptosis. In contrast, the response in the red spectral range is different for the two cell lines and may be ascribed to a different iron homeostasis.
Delayed Cell Cycle Progression and Apoptosis Induced by Hemicellulase-Treated Agaricus blazei
Kasai, Hirotake
2007-01-01
We examined the effects of hemicellulase-treated Agaricus blazei (AB fraction H, ABH) on growth of several tumor cell lines. ABH inhibited the proliferation of some cell lines without cytotoxic effects. It markedly prolonged the S phase of the cell cycle. ABH also induced mitochondria-mediated apoptosis in different cell lines. However, it had no impact on the growth of other cell lines. ABH induced strong activation of p38 mitogen-activated protein kinase (MAPK) in the cells in which it evoked apoptosis. On the other hand, ABH showed only a weak p38 activation effect in those cell lines in which it delayed cell cycle progression with little induction of apoptosis. However, p38 MAPK-specific inhibitor inhibited both ABH-induced effects, and ABH also caused apoptosis in the latter cells under conditions of high p38 MAPK activity induced by combined treatment with TNF-α. These results indicate that the responsiveness of p38 MAPK to ABH, which differs between cell lines, determines subsequent cellular responses on cell growth. PMID:17342245
Modeling the global positioning system signal propagation through the ionosphere
NASA Technical Reports Server (NTRS)
Bassiri, S.; Hajj, G. A.
1992-01-01
Based on realistic modeling of the electron density of the ionosphere and using a dipole moment approximation for the Earth's magnetic field, one is able to estimate the effect of the ionosphere on the Global Positioning System (GPS) signal for a ground user. The lowest order effect, which is on the order of 0.1-100 m of group delay, is subtracted out by forming a linear combination of the dual frequencies of the GPS signal. One is left with second- and third-order effects that are estimated typically to be approximately 0-2 cm and approximately 0-2 mm at zenith, respectively, depending on the geographical location, the time of day, the time of year, the solar cycle, and the relative geometry of the magnetic field and the line of sight. Given the total electron content along a line of sight, the authors derive an approximation to the second-order term which is accurate to approximately 90 percent within the magnetic dipole moment model; this approximation can be used to reduce the second-order term to the millimeter level, thus potentially improving precise positioning in space and on the ground. The induced group delay, or phase advance, due to second- and third-order effects is examined for two ground receivers located at equatorial and mid-latitude regions tracking several GPS satellites.
Kumar, Santosh; Jordan, Mark C; Datla, Raju; Cloutier, Sylvie
2013-01-01
As a crop, flax holds significant commercial value for its omega-3 rich oilseeds and stem fibres. Canada is the largest producer of linseed but there exists scope for significant yield improvements. Implementation of mechanisms such as male sterility can permit the development of hybrids to assist in achieving this goal. Temperature sensitive male sterility has been reported in flax but the leakiness of this system in field conditions limits the production of quality hybrid seeds. Here, we characterized a 2,588 bp transcript differentially expressed in male sterile lines of flax. The twelve intron gene predicted to encode a 368 amino acid protein has five WD40 repeats which, in silico, form a propeller structure with putative nucleic acid and histone binding capabilities. The LuWD40-1 protein localized to the nucleus and its expression increased during the transition and continued through the vegetative stages (seed, etiolated seedling, stem) while the transcript levels declined during reproductive development (ovary, anthers) and embryonic morphogenesis of male fertile plants. Knockout lines for LuWD40-1 in flax failed to develop shoots while overexpression lines showed delayed growth phenotype and were male sterile. The non-viable flowers failed to open and the pollen grains from these flowers were empty. Three independent transgenic lines overexpressing the LuWD40-1 gene had ∼80% non-viable pollen, reduced branching, delayed flowering and maturity compared to male fertile genotypes. The present study provides new insights into a male sterility mechanism present in flax.
NASA Astrophysics Data System (ADS)
Sluse, D.; Tewes, M.
2014-11-01
The advent of large area photometric surveys has raised a great deal of interest in the possibility of using broadband photometric data, instead of spectra, to measure the size of the broad line region of active galactic nuclei. We describe here a new method that uses time-delay lensed quasars where one or several images are affected by microlensing due to stars in the lensing galaxy. Because microlensing decreases (or increases) the flux of the continuum compared to the broad line region, it changes the contrast between these two emission components. We show that this effect can be used to effectively disentangle the intrinsic variability of those two regions, offering the opportunity to perform reverberation mapping based on single-band photometric data. Based on simulated light curves generated using a damped random walk model of quasar variability, we show that measurement of the size of the broad line region can be achieved using this method, provided one spectrum has been obtained independently during the monitoring. This method is complementary to photometric reverberation mapping and could also be extended to multi-band data. Because the effect described above produces a variability pattern in difference light curves between pairs of lensed images that is correlated with the time-lagged continuum variability, it can potentially produce systematic errors in measurement of time delays between pairs of lensed images. Simple simulations indicate that time-delay measurement techniques that use a sufficiently flexible model for the extrinsic variability are not affected by this effect and produce accurate time delays.
Delay Discounting and Intelligence: A Meta-Analysis
ERIC Educational Resources Information Center
Shamosh, Noah A.; Gray, Jeremy R.
2008-01-01
Delay discounting (DD), the tendency to prefer smaller, sooner rewards to larger, later ones, is an important indicator of self-control. Assessments of DD superficially require individuals to make choices based on motivational processes. However, several lines of evidence suggest that DD may be systematically related to cognitive ability. We…
Wide Band Low Noise Love Wave Magnetic Field Sensor System.
Kittmann, Anne; Durdaut, Phillip; Zabel, Sebastian; Reermann, Jens; Schmalz, Julius; Spetzler, Benjamin; Meyners, Dirk; Sun, Nian X; McCord, Jeffrey; Gerken, Martina; Schmidt, Gerhard; Höft, Michael; Knöchel, Reinhard; Faupel, Franz; Quandt, Eckhard
2018-01-10
We present a comprehensive study of a magnetic sensor system that benefits from a new technique to substantially increase the magnetoelastic coupling of surface acoustic waves (SAW). The device uses shear horizontal acoustic surface waves that are guided by a fused silica layer with an amorphous magnetostrictive FeCoSiB thin film on top. The velocity of these so-called Love waves follows the magnetoelastically-induced changes of the shear modulus according to the magnetic field present. The SAW sensor is operated in a delay line configuration at approximately 150 MHz and translates the magnetic field to a time delay and a related phase shift. The fundamentals of this sensor concept are motivated by magnetic and mechanical simulations. They are experimentally verified using customized low-noise readout electronics. With an extremely low magnetic noise level of ≈100 pT/[Formula: see text], a bandwidth of 50 kHz and a dynamic range of 120 dB, this magnetic field sensor system shows outstanding characteristics. A range of additional measures to further increase the sensitivity are investigated with simulations.
Topological Acoustic Delay Line
NASA Astrophysics Data System (ADS)
Zhang, Zhiwang; Tian, Ye; Cheng, Ying; Wei, Qi; Liu, Xiaojun; Christensen, Johan
2018-03-01
Topological protected wave engineering in artificially structured media is at the frontier of ongoing metamaterials research that is inspired by quantum mechanics. Acoustic analogues of electronic topological insulators have recently led to a wealth of new opportunities in manipulating sound propagation with strikingly unconventional acoustic edge modes immune to backscattering. Earlier fabrications of topological insulators are characterized by an unreconfigurable geometry and a very narrow frequency response, which severely hinders the exploration and design of useful devices. Here we establish topologically protected sound in reconfigurable phononic crystals that can be switched on and off simply by rotating its three-legged "atoms" without altering the lattice structure. In particular, we engineer robust phase delay defects that take advantage of the ultrabroadband reflection-free sound propagation. Such topological delay lines serve as a paradigm in compact acoustic devices, interconnects, and electroacoustic integrated circuits.
Feedback control of flow vorticity at low Reynolds numbers.
Zeitz, Maria; Gurevich, Pavel; Stark, Holger
2015-03-01
Our aim is to explore strategies of feedback control to design and stabilize novel dynamic flow patterns in model systems of complex fluids. To introduce the control strategies, we investigate the simple Newtonian fluid at low Reynolds number in a circular geometry. Then, the fluid vorticity satisfies a diffusion equation. We determine the mean vorticity in the sensing area and use two control strategies to feed it back into the system by controlling the angular velocity of the circular boundary. Hysteretic feedback control generates self-regulated stable oscillations in time, the frequency of which can be adjusted over several orders of magnitude by tuning the relevant feedback parameters. Time-delayed feedback control initiates unstable vorticity modes for sufficiently large feedback strength. For increasing delay time, we first observe oscillations with beats and then regular trains of narrow pulses. Close to the transition line between the resting fluid and the unstable modes, these patterns are relatively stable over long times.
New mouse tumor model system (RIF-1) for comparison of end-point studies
DOE Office of Scientific and Technical Information (OSTI.GOV)
Twentyman, P.R.; Brown, J.M.; Gray, J.W.
1980-03-01
A new tumor model system (RIF-1) was developed that is very suitable for studies in which clonogenic survival is compared with growth delay and control probability following various forms of treatment. The tumor was a radiation-induced sarcoma in the inbred female C3H/Km mouse. It had a low median tumor dose, had a satisfactory plating efficiency direct from in vivo to in vitro, was nonimmunogenic or minimally immunogenic, and metastasized only at a relatively advanced stage of growth. The cell line grew either as a monolayer on plastic dishes, as tumor spheroids in spinner culture, as lung nodules following injection ofmore » a single-cell suspension into the tall veins of syngeneic mice, or as a solid tumor. Both diploid and tetraploid clonogenic cells were found in monolayer cultures of the RIF-1 line.« less
Delivery and application of precise timing for a traveling wave powerline fault locator system
NASA Technical Reports Server (NTRS)
Street, Michael A.
1990-01-01
The Bonneville Power Administration (BPA) has successfully operated an in-house developed powerline fault locator system since 1986. The BPA fault locator system consists of remotes installed at cardinal power transmission line system nodes and a central master which polls the remotes for traveling wave time-of-arrival data. A power line fault produces a fast rise-time traveling wave which emanates from the fault point and propagates throughout the power grid. The remotes time-tag the traveling wave leading edge as it passes through the power system cardinal substation nodes. A synchronizing pulse transmitted via the BPA analog microwave system on a wideband channel sychronizes the time-tagging counters in the remote units to a different accuracy of better than one microsecond. The remote units correct the raw time tags for synchronizing pulse propagation delay and return these corrected values to the fault locator master. The master then calculates the power system disturbance source using the collected time tags. The system design objective is a fault location accuracy of 300 meters. BPA's fault locator system operation, error producing phenomena, and method of distributing precise timing are described.
A Time-Domain CMOS Oscillator-Based Thermostat with Digital Set-Point Programming
Chen, Chun-Chi; Lin, Shih-Hao
2013-01-01
This paper presents a time-domain CMOS oscillator-based thermostat with digital set-point programming [without a digital-to-analog converter (DAC) or external resistor] to achieve on-chip thermal management of modern VLSI systems. A time-domain delay-line-based thermostat with multiplexers (MUXs) was used to substantially reduce the power consumption and chip size, and can benefit from the performance enhancement due to the scaling down of fabrication processes. For further cost reduction and accuracy enhancement, this paper proposes a thermostat using two oscillators that are suitable for time-domain curvature compensation instead of longer linear delay lines. The final time comparison was achieved using a time comparator with a built-in custom hysteresis to generate the corresponding temperature alarm and control. The chip size of the circuit was reduced to 0.12 mm2 in a 0.35-μm TSMC CMOS process. The thermostat operates from 0 to 90 °C, and achieved a fine resolution better than 0.05 °C and an improved inaccuracy of ± 0.6 °C after two-point calibration for eight packaged chips. The power consumption was 30 μW at a sample rate of 10 samples/s. PMID:23385403
Ko, Hyun-Ja; Kinkel, Sarah A; Hubert, François-Xavier; Nasa, Zeyad; Chan, James; Siatskas, Christopher; Hirubalan, Premila; Toh, Ban-Hock; Scott, Hamish S; Alderuccio, Frank
2010-12-01
The autoimmune regulator (AIRE) promotes "promiscuous" expression of tissue-restricted antigens (TRA) in thymic medullary epithelial cells to facilitate thymic deletion of autoreactive T-cells. Here, we show that AIRE-deficient mice showed an earlier development of myelin oligonucleotide glycoprotein (MOG)-induced experimental autoimmune encephalomyelitis (EAE). To determine the outcome of ectopic Aire expression, we used a retroviral transduction system to over-express Aire in vitro, in cell lines and in bone marrow (BM). In the cell lines that included those of thymic medullary and dendritic cell origin, ectopically expressed Aire variably promoted expression of TRA including Mog and Ins2 (proII) autoantigens associated, respectively, with the autoimmune diseases multiple sclerosis and type 1 diabetes. BM chimeras generated from BM transduced with a retrovirus encoding Aire displayed elevated levels of Mog and Ins2 expression in thymus and spleen. Following induction of EAE with MOG(35-55), transplanted mice displayed significant delay in the onset of EAE compared with control mice. To our knowledge, this is the first example showing that in vivo ectopic expression of AIRE can modulate TRA expression and alter autoimmune disease development. Copyright © 2010 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Simulation to coating weight control for galvanizing
NASA Astrophysics Data System (ADS)
Wang, Junsheng; Yan, Zhang; Wu, Kunkui; Song, Lei
2013-05-01
Zinc coating weight control is one of the most critical issues for continuous galvanizing line. The process has the characteristic of variable-time large time delay, nonlinear, multivariable. It can result in seriously coating weight error and non-uniform coating. We develop a control system, which can automatically control the air knives pressure and its position to give a constant and uniform zinc coating, in accordance with customer-order specification through an auto-adaptive empirical model-based feed forward adaptive controller, and two model-free adaptive feedback controllers . The proposed models with controller were applied to continuous galvanizing line (CGL) at Angang Steel Works. By the production results, the precise and stability of the control model reduces over-coating weight and improves coating uniform. The product for this hot dip galvanizing line does not only satisfy the customers' quality requirement but also save the zinc consumption.
Break-before-make CMOS inverter for power-efficient delay implementation.
Puhan, Janez; Raič, Dušan; Tuma, Tadej; Bűrmen, Árpád
2014-01-01
A modified static CMOS inverter with two inputs and two outputs is proposed to reduce short-circuit current in order to increment delay and reduce power overhead where slow operation is required. The circuit is based on bidirectional delay element connected in series with the PMOS and NMOS switching transistors. It provides differences in the dynamic response so that the direct-path current in the next stage is reduced. The switching transistors are never ON at the same time. Characteristics of various delay element implementations are presented and verified by circuit simulations. Global optimization procedure is used to obtain the most power-efficient transistor sizing. The performance of the modified CMOS inverter chain is compared to standard implementation for various delays. The energy (charge) per delay is reduced up to 40%. The use of the proposed delay element is demonstrated by implementing a low-power delay line and a leading-edge detector cell.
Break-before-Make CMOS Inverter for Power-Efficient Delay Implementation
Raič, Dušan
2014-01-01
A modified static CMOS inverter with two inputs and two outputs is proposed to reduce short-circuit current in order to increment delay and reduce power overhead where slow operation is required. The circuit is based on bidirectional delay element connected in series with the PMOS and NMOS switching transistors. It provides differences in the dynamic response so that the direct-path current in the next stage is reduced. The switching transistors are never ON at the same time. Characteristics of various delay element implementations are presented and verified by circuit simulations. Global optimization procedure is used to obtain the most power-efficient transistor sizing. The performance of the modified CMOS inverter chain is compared to standard implementation for various delays. The energy (charge) per delay is reduced up to 40%. The use of the proposed delay element is demonstrated by implementing a low-power delay line and a leading-edge detector cell. PMID:25538951
A REVERBERATION-BASED BLACK HOLE MASS FOR MCG-06-30-15
DOE Office of Scientific and Technical Information (OSTI.GOV)
Bentz, Misty C.; Crenshaw, D. Michael; Ou-Yang, Benjamin
2016-10-20
We present the results of a reverberation campaign targeting MGC-06-30-15. Spectrophotometric monitoring and broad-band photometric monitoring over the course of four months in spring 2012 allowed a determination of a time delay in the broad H β emission line of τ = 5.3 ± 1.8 days in the rest frame of the active galactic nucleus (AGN). Combined with the width of the variable portion of the emission line, we determine a black hole mass of M {sub BH} = (1.6 ± 0.4) × 10{sup 6} M {sub ⊙}. Both the H β time delay and the black hole mass aremore » in good agreement with expectations from the R {sub BLR}– L and M {sub BH}– σ {sub ⋆} relationships for other reverberation-mapped AGNs. The H β time delay is also in good agreement with the relationship between H β and broad-band near-IR delays, in which the effective size of the broad-line region is ∼4–5 times smaller than the inner edge of the dust torus. Additionally, the reverberation-based mass is in good agreement with estimates from the scaling relationship of the break in the X-ray power spectral density, and with constraints based on stellar kinematics derived from integral field spectroscopy of the inner ∼0.5 kpc of the galaxy.« less
NASA Astrophysics Data System (ADS)
Al-Jader, M. A.; Cullen, J. D.; Shaw, Andy; Al-Shamma'a, A. I.
2011-08-01
Currently there are about 4300 weld points on the average steel vehicle. Errors and problems due to tip damage and wear can cause great losses due to production line downtime. Current industrial monitoring systems check the quality of the nugget after processing 15 cars average once every two weeks. The nuggets are examined off line using a destructive process, which takes approximately 10 days to complete causing a long delay in the production process. In this paper a simulation results using software package, SORPAS, will be presented to determined the sustainability factors in spot welding process including Voltage, Current, Force, Water cooling rates, Material thicknesses and usage. The experimental results of various spot welding processes will be investigated and reported. The correlation of experimental results shows that SORPAS simulations can be used as an off line measurement to reduce factory energy usage. This paper also provides an overview of electrode current selection and its variance over the lifetime of the electrode tip, and describes the proposed analysis system for the selection of welding parameters for the spot welding process, as the electrode tip wears.
Acoustic Wave Propagation in Pressure Sense Lines
NASA Technical Reports Server (NTRS)
Vitarius, Patrick; Gregory, Don A.; Wiley, John; Korman, Valentin
2003-01-01
Sense lines are used in pressure measurements to passively transmit information from hostile environments to areas where transducers can be used. The transfer function of a sense line can be used to obtain information about the measured environment from the protected sensor. Several properties of this transfer function are examined, including frequency dependence, Helmholtz resonance, and time of flight delay.
Submillimeter bolt location in car bodywork for production line quality inspection
NASA Astrophysics Data System (ADS)
Altamirano-Robles, Leopoldo; Arias-Estrada, Miguel; Alviso-Quibrera, Samuel; Lopez-Lopez, Aurelio
2000-03-01
In the automotive industry, a vehicle begins with the construction of the vehicle floor. Later on, several robots weld a series of bolts to this floor which are used to fix other parts. Due to several problems, like welding tools wearing, robot miscalibration or momentary low power supply, among others, some bolts are incorrectly positioned or are not present at all, bringing problems and delays in the next work cells. Therefore, it is of importance to verify the quality of welded parts before the following assembly steps. A computer vision system is proposed in order to locate autonomously the presence and quality of the bolts. The system should carry on the inspection in real time at the car assembly line under the following conditions: without touching the bodywork, with a precision in the submillimeter range and in few seconds. In this paper we present a basic computer vision system for bolt location in the submillimeter range. We analyze three arrangements of the system components (camera and illumination sources) that produce different results in the localization. Results are presented and compared for the three approaches obtained under laboratory conditions. The algorithms were tested in the assembling line. Variations up to one millimeter in the welded position of the bolts were observed.
Multiple-hypothesis multiple-model line tracking
NASA Astrophysics Data System (ADS)
Pace, Donald W.; Owen, Mark W.; Cox, Henry
2000-07-01
Passive sonar signal processing generally includes tracking of narrowband and/or broadband signature components observed on a Lofargram or on a Bearing-Time-Record (BTR) display. Fielded line tracking approaches to date have been recursive and single-hypthesis-oriented Kalman- or alpha-beta filters, with no mechanism for considering tracking alternatives beyond the most recent scan of measurements. While adaptivity is often built into the filter to handle changing track dynamics, these approaches are still extensions of single target tracking solutions to multiple target tracking environment. This paper describes an application of multiple-hypothesis, multiple target tracking technology to the sonar line tracking problem. A Multiple Hypothesis Line Tracker (MHLT) is developed which retains the recursive minimum-mean-square-error tracking behavior of a Kalman Filter in a maximum-a-posteriori delayed-decision multiple hypothesis context. Multiple line track filter states are developed and maintained using the interacting multiple model (IMM) state representation. Further, the data association and assignment problem is enhanced by considering line attribute information (line bandwidth and SNR) in addition to beam/bearing and frequency fit. MHLT results on real sonar data are presented to demonstrate the benefits of the multiple hypothesis approach. The utility of the system in cluttered environments and particularly in crossing line situations is shown.
Long microwave delay fiber-optic link for radar testing
NASA Astrophysics Data System (ADS)
Newberg, I. L.; Gee, C. M.; Thurmond, G. D.; Yen, H. W.
1990-05-01
A long fiberoptic delay line is used as a radar repeater to improve radar testing capabilities. The first known generation of 152 microsec delayed ideal target at X-band (10 GHz) frequencies having the phase stability and signal-to-noise ratio (SNR) needed for testing modern high-resolution Doppler radars is demonstrated with a 31.6-km experimental externally modulated fiberoptic link with a distributed-feedback (DFB) laser. The test application, link configuration, and link testing are discussed.
Delay-induced wave instabilities in single-species reaction-diffusion systems
NASA Astrophysics Data System (ADS)
Otto, Andereas; Wang, Jian; Radons, Günter
2017-11-01
The Turing (wave) instability is only possible in reaction-diffusion systems with more than one (two) components. Motivated by the fact that a time delay increases the dimension of a system, we investigate the presence of diffusion-driven instabilities in single-species reaction-diffusion systems with delay. The stability of arbitrary one-component systems with a single discrete delay, with distributed delay, or with a variable delay is systematically analyzed. We show that a wave instability can appear from an equilibrium of single-species reaction-diffusion systems with fluctuating or distributed delay, which is not possible in similar systems with constant discrete delay or without delay. More precisely, we show by basic analytic arguments and by numerical simulations that fast asymmetric delay fluctuations or asymmetrically distributed delays can lead to wave instabilities in these systems. Examples, for the resulting traveling waves are shown for a Fisher-KPP equation with distributed delay in the reaction term. In addition, we have studied diffusion-induced instabilities from homogeneous periodic orbits in the same systems with variable delay, where the homogeneous periodic orbits are attracting resonant periodic solutions of the system without diffusion, i.e., periodic orbits of the Hutchinson equation with time-varying delay. If diffusion is introduced, standing waves can emerge whose temporal period is equal to the period of the variable delay.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Barraclough, B; Park, J; Li, F
2016-06-15
Purpose: To report the development and characterization of the first in-house gating system implemented with an optical tracking system (OTS) and the Elekta Response™ interface. Methods: The Response™ connects a patient tracking system with a linac, enabling the tracking system to control radiation delivery. The developed system uses an in-house OTS to monitor patient breathing. The OTS consists of two infrared-based cameras, tracking markers affixed on patient. It achieves gated or breath-held (BH) treatment by calling beam ON/OFF functions in the Response™ dynamic-link library (DLL). A 4D motion phantom was used to evaluate its dosimetric and time delay characteristics. Twomore » FF- and two FFF-IMRT beams were delivered in non-gated, BH and gated mode. The sinusoidal gating signal had a 6 sec period and 15 mm amplitude. The duty cycle included 10%, 20%, 30% and 50%. The BH signal was adapted from the sinusoidal wave by inserting 15 sec BHs. Each delivery was measured with a 2D diode array (MapCHECK™) and compared with the non-gated delivery using gamma analysis (3%). The beam ON/OFF time was captured using the service graphing utility of the linac. Results: The gated treatments were successfully delivered except the 10% duty cycle. The BH delivery had perfect agreement (100%) with non-gated delivery; the agreement of gated delivery decreased from 99% to 88% as duty cycle reduced from 50% to 20%. The beam on/off delay was on average 0.25/0.06 sec. The delivery time for the 50%, 30% and 20% duty cycle increased by 29%, 71% and 139%, respectively. No dosimetric or time delay difference was noticed between FF- and FFF-IMRT beams. Conclusion: The in-house gating system was successfully developed with dosimetric and time delay characteristics in line with published results for commercial systems. It will be an important platform for further research and clinical development of gated treatment.« less
Astronaut activity in weightlessness and unsupported space
NASA Technical Reports Server (NTRS)
Ivanov, Y. A.; Popov, V. A.; Kachaturyants, L. S.
1975-01-01
For the purpose of study of the performance ability of a human operator in prolonged weightless conditions was studied by the following methods: (1) psychophysiological analysis of certain operations; (2) the dynamic characteristics of a man, included in a model control system, with direct and delayed feedback; (3) evaluation of the singularities of analysis and quality of the working memory, in working with outlines of patterned and random lines; and (4) biomechanical analysis of spatial orientation and motor activity in unsupported space.
Development of a high-sensitivity strain measurement system based on a SH SAW sensor
NASA Astrophysics Data System (ADS)
Oh, Haekwan; Lee, Keekeun; Eun, Kyoungtae; Choa, Sung-Hoon; Yang, Sang Sik
2012-02-01
A strain measurement system based on a shear horizontal surface acoustic wave (SH SAW) was developed. The developed system is composed of a SAW microsensor, a printed circuit board (PCB), an adhesive and a strain gauge. When a compression force is applied to the PCB by the strain gauge, the PCB is bent so that external strain energy can be evenly delivered to the microsensor without any detachment of the sensor from the board. When a stretching force is applied to the PCB under the condition that one side of the PCB is fixed and the other side is modulated, the actual length of the SAW delay line between the two interdigital transducers (IDTs) is increased. The increase in the delay line length causes a change in the time for the propagating SAW to reach the output IDT. If strain energy is applied to the piezoelectric substrate, the substrate density is changed, which then changes the propagation velocity of the SAW. Coupling-of-modes modeling was conducted prior to fabrication to determine the optimal device parameters. Depending on the strain, the frequency difference was linearly modulated. The obtained sensitivity for stretching was 17.3 kHz/% for the SH wave mode and split electrode. And the obtained sensitivity for bending was 46.1 kHz/% for the SH wave mode and split electrode. The SH wave showed about 15% higher sensitivity than the Rayleigh wave, and the dog-bone PCB showed about 8% higher sensitivity than the rectangular PCB. The obtained sensitivity was about five times higher than that of existing SAW-based strain sensors.
Neutron-$$\\gamma$$ competition for β-delayed neutron emission
Mumpower, Matthew Ryan; Kawano, Toshihiko; Moller, Peter
2016-12-19
Here we present a coupled quasiparticle random phase approximation and Hauser-Feshbach (QRPA+HF) model for calculating delayed particle emission. This approach uses microscopic nuclear structure information, which starts with Gamow-Teller strength distributions in the daughter nucleus and then follows the statistical decay until the initial available excitation energy is exhausted. Explicitly included at each particle emission stage is γ-ray competition. We explore this model in the context of neutron emission of neutron-rich nuclei and find that neutron-γ competition can lead to both increases and decreases in neutron emission probabilities, depending on the system considered. Finally, a second consequence of this formalismmore » is a prediction of more neutrons on average being emitted after β decay for nuclei near the neutron drip line compared to models that do not consider the statistical decay.« less
NASA Astrophysics Data System (ADS)
Kaba, M.; Zhou, F. C.; Lim, A.; Decoster, D.; Huignard, J.-P.; Tonda, S.; Dolfi, D.; Chazelas, J.
2007-11-01
The applications of microwave optoelectronics are extremely large since they extend from the Radio-over-Fibre to the Homeland security and defence systems. Then, the improved maturity of the optoelectronic components operating up to 40GHz permit to consider new optical processing functions (filtering, beamforming, ...) which can operate over very wideband microwave analogue signals. Specific performances are required which imply optical delay lines able to exhibit large Time-Bandwidth product values. It is proposed to evaluate slow light approach through highly dispersive structures based on either uniform or chirped Bragg Gratings. Therefore, we highlight the impact of the major parameters of such structures: index modulation depth, grating length, grating period, chirp coefficient and demonstrate the high potentiality of Bragg Grating for Large RF signals bandwidth processing under slow-light propagation.
Pipelined digital SAR azimuth correlator using hybrid FFT-transversal filter
NASA Technical Reports Server (NTRS)
Wu, C.; Liu, K. Y. (Inventor)
1984-01-01
A synthetic aperture radar system (SAR) having a range correlator is provided with a hybrid azimuth correlator which utilizes a block-pipe-lined fast Fourier transform (FFT). The correlator has a predetermined FFT transform size with delay elements for delaying SAR range correlated data so as to embed in the Fourier transform operation a corner-turning function as the range correlated SAR data is converted from the time domain to a frequency domain. The azimuth correlator is comprised of a transversal filter to receive the SAR data in the frequency domain, a generator for range migration compensation and azimuth reference functions, and an azimuth reference multiplier for correlation of the SAR data. Following the transversal filter is a block-pipelined inverse FFT used to restore azimuth correlated data in the frequency domain to the time domain for imaging.
NASA Astrophysics Data System (ADS)
Chen, Yuan-Ho
2017-05-01
In this work, we propose a counting-weighted calibration method for field-programmable-gate-array (FPGA)-based time-to-digital converter (TDC) to provide non-linearity calibration for use in positron emission tomography (PET) scanners. To deal with the non-linearity in FPGA, we developed a counting-weighted delay line (CWD) to count the delay time of the delay cells in the TDC in order to reduce the differential non-linearity (DNL) values based on code density counts. The performance of the proposed CWD-TDC with regard to linearity far exceeds that of TDC with a traditional tapped delay line (TDL) architecture, without the need for nonlinearity calibration. When implemented in a Xilinx Vertix-5 FPGA device, the proposed CWD-TDC achieved time resolution of 60 ps with integral non-linearity (INL) and DNL of [-0.54, 0.24] and [-0.66, 0.65] least-significant-bit (LSB), respectively. This is a clear indication of the suitability of the proposed FPGA-based CWD-TDC for use in PET scanners.
A New Relationship Between Soft X-Rays and EUV Flare Light Curves
NASA Astrophysics Data System (ADS)
Thiemann, Edward
2016-05-01
Solar flares are the result of magnetic reconnection in the solar corona which converts magnetic energy into kinetic energy resulting in the rapid heating of solar plasma. As this plasma cools, it emits radiation at different EUV wavelengths when the dropping temperature passes a line’s temperature of formation. This results in a delay in the emissions from cooler EUV lines relative to hotter EUV lines. Therefore, characterizing how this hot plasma cools is important for understanding how the corresponding geo-effective extreme ultraviolet (EUV) irradiance evolves in time. I present a simple new framework in which to study flare cooling by using a Lumped Element Thermal Model (LETM). LETM is frequently used in science and engineering to simplify a complex multi-dimensional thermal system by reducing it to a 0-D thermal circuit. For example, a structure that conducts heat out of a system is simplified with a resistive element and a structure that allows a system to store heat is simplified with a capacitive element. A major advantage of LETM is that the specific geometry of a system can be ignored, allowing for an intuitive analysis of the major thermal processes. I show that LETM is able to accurately reproduce the temporal evolution of cooler flare emission lines based on hotter emission line evolution. In particular, it can be used to predict the evolution of EUV flare light curves using the NOAA X-Ray Sensor (XRS).
Conical-Domain Model for Estimating GPS Ionospheric Delays
NASA Technical Reports Server (NTRS)
Sparks, Lawrence; Komjathy, Attila; Mannucci, Anthony
2009-01-01
The conical-domain model is a computational model, now undergoing development, for estimating ionospheric delays of Global Positioning System (GPS) signals. Relative to the standard ionospheric delay model described below, the conical-domain model offers improved accuracy. In the absence of selective availability, the ionosphere is the largest source of error for single-frequency users of GPS. Because ionospheric signal delays contribute to errors in GPS position and time measurements, satellite-based augmentation systems (SBASs) have been designed to estimate these delays and broadcast corrections. Several national and international SBASs are currently in various stages of development to enhance the integrity and accuracy of GPS measurements for airline navigation. In the Wide Area Augmentation System (WAAS) of the United States, slant ionospheric delay errors and confidence bounds are derived from estimates of vertical ionospheric delay modeled on a grid at regularly spaced intervals of latitude and longitude. The estimate of vertical delay at each ionospheric grid point (IGP) is calculated from a planar fit of neighboring slant delay measurements, projected to vertical using a standard, thin-shell model of the ionosphere. Interpolation on the WAAS grid enables estimation of the vertical delay at the ionospheric pierce point (IPP) corresponding to any arbitrary measurement of a user. (The IPP of a given user s measurement is the point where the GPS signal ray path intersects a reference ionospheric height.) The product of the interpolated value and the user s thin-shell obliquity factor provides an estimate of the user s ionospheric slant delay. Two types of error that restrict the accuracy of the thin-shell model are absent in the conical domain model: (1) error due to the implicit assumption that the electron density is independent of the azimuthal angle at the IPP and (2) error arising from the slant-to-vertical conversion. At low latitudes or at mid-latitudes under disturbed conditions, the accuracy of SBAS systems based upon the thin-shell model suffers due to the presence of complex ionospheric structure, high delay values, and large electron density gradients. Interpolation on the vertical delay grid serves as an additional source of delay error. The conical-domain model permits direct computation of the user s slant delay estimate without the intervening use of a vertical delay grid. The key is to restrict each fit of GPS measurements to a spatial domain encompassing signals from only one satellite. The conical domain model is so named because each fit involves a group of GPS receivers that all receive signals from the same GPS satellite (see figure); the receiver and satellite positions define a cone, the satellite position being the vertex. A user within a given cone evaluates the delay to the satellite directly, using (1) the IPP coordinates of the line of sight to the satellite and (2) broadcast fit parameters associated with the cone. The conical-domain model partly resembles the thin-shell model in that both models reduce an inherently four-dimensional problem to two dimensions. However, unlike the thin-shell model, the conical domain model does not involve any potentially erroneous simplifying assumptions about the structure of the ionosphere. In the conical domain model, the initially four-dimensional problem becomes truly two-dimensional in the sense that once a satellite location has been specified, any signal path emanating from a satellite can be identified by only two coordinates; for example, the IPP coordinates. As a consequence, a user s slant-delay estimate converges to the correct value in the limit that the receivers converge to the user s location (or, equivalently, in the limit that the measurement IPPs converge to the user s IPP).
Ding, Tingting; Zheng, Yuanlin; Chen, Xianfeng
2018-04-30
Configurable narrow bandwidth filters are indispensable components in optical communication networks. Here, we present an easily-integrated compact tunable filtering based on polarization-coupling process in a thin periodically poled lithium niobate (PPLN) in a reflective geometry via the transverse electro-optic (EO) effect. The structure, composed of an in-line polarizer and a thinned PPLN chip, forms a phase-shift Solc-type filter with similar mechanism to defected Bragg gratings. The filtering effect can be dynamically switched on and off by a transverse electric filed. Analogy of electromagnetically induced transparency (EIT) transmission spectrum and electrically controllable group delay is experimentally observed. The mechanism features tunable center wavelength in a wide range with respect to temperature and tunable optical delay to the applied voltage, which may offer another way for optical tunable filters or delay lines.
Efferent feedback can explain many hearing phenomena
NASA Astrophysics Data System (ADS)
Holmes, W. Harvey; Flax, Matthew R.
2015-12-01
The mixed mode cochlear amplifier (MMCA) model was presented at the last Mechanics of Hearing workshop [4]. The MMCA consists principally of a nonlinear feedback loop formed when an efferent-controlled outer hair cell (OHC) is combined with the cochlear mechanics and the rest of the relevant neurobiology. Essential elements of this model are efferent control of the OHC motility and a delay in the feedback to the OHC. The input to the MMCA is the passive travelling wave. In the MMCA amplification is localized where both the neural and tuned mechanical systems meet in the Organ of Corti (OoC). The simplest model based on this idea is a nonlinear delay line resonator (DLR), which is mathematically described by a nonlinear delay-differential equation (DDE). This model predicts possible Hopf bifurcations and exhibits its most interesting behaviour when operating near a bifurcation. This contribution presents some simulation results using the DLR model. These show that various observed hearing phenomena can be accounted for by this model, at least qualitatively, including compression effects, two-tone suppression and some forms of otoacoustic emissions (OAEs).
NASA Astrophysics Data System (ADS)
Niu, Xiaofeng; Ye, Hongwei; Xia, Ting; Asma, Evren; Winkler, Mark; Gagnon, Daniel; Wang, Wenli
2015-07-01
Quantitative PET imaging is widely used in clinical diagnosis in oncology and neuroimaging. Accurate normalization correction for the efficiency of each line-of- response is essential for accurate quantitative PET image reconstruction. In this paper, we propose a normalization calibration method by using the delayed-window coincidence events from the scanning phantom or patient. The proposed method could dramatically reduce the ‘ring’ artifacts caused by mismatched system count-rates between the calibration and phantom/patient datasets. Moreover, a modified algorithm for mean detector efficiency estimation is proposed, which could generate crystal efficiency maps with more uniform variance. Both phantom and real patient datasets are used for evaluation. The results show that the proposed method could lead to better uniformity in reconstructed images by removing ring artifacts, and more uniform axial variance profiles, especially around the axial edge slices of the scanner. The proposed method also has the potential benefit to simplify the normalization calibration procedure, since the calibration can be performed using the on-the-fly acquired delayed-window dataset.
Ground-Based GPS Sensing of Azimuthal Variations in Precipitable Water Vapor
NASA Technical Reports Server (NTRS)
Kroger, P. M.; Bar-Sever, Y. E.
1997-01-01
Current models for troposphere delay employed by GPS software packages map the total zenith delay to the line-of-sight delay of the individual satellite-receiver link under the assumption of azimuthal homogeneity. This could be a poor approximation for many sites, in particular, those located at an ocean front or next to a mountain range. We have modified the GIPSY-OASIS II software package to include a simple non-symmetric mapping function (MacMillan, 1995) which introduces two new parameters.
Surface acoustic wave devices as passive buried sensors
NASA Astrophysics Data System (ADS)
Friedt, J.-M.; Rétornaz, T.; Alzuaga, S.; Baron, T.; Martin, G.; Laroche, T.; Ballandras, S.; Griselin, M.; Simonnet, J.-P.
2011-02-01
Surface acoustic wave (SAW) devices are currently used as passive remote-controlled sensors for measuring various physical quantities through a wireless link. Among the two main classes of designs—resonator and delay line—the former has the advantage of providing narrow-band spectrum informations and hence appears compatible with an interrogation strategy complying with Industry-Scientific-Medical regulations in radio-frequency (rf) bands centered around 434, 866, or 915 MHz. Delay-line based sensors require larger bandwidths as they consists of a few interdigitated electrodes excited by short rf pulses with large instantaneous energy and short response delays but is compatible with existing equipment such as ground penetrating radar (GPR). We here demonstrate the measurement of temperature using the two configurations, particularly for long term monitoring using sensors buried in soil. Although we have demonstrated long term stability and robustness of packaged resonators and signal to noise ratio compatible with the expected application, the interrogation range (maximum 80 cm) is insufficient for most geology or geophysical purposes. We then focus on the use of delay lines, as the corresponding interrogation method is similar to the one used by GPR which allows for rf penetration distances ranging from a few meters to tens of meters and which operates in the lower rf range, depending on soil water content, permittivity, and conductivity. Assuming propagation losses in a pure dielectric medium with negligible conductivity (snow or ice), an interrogation distance of about 40 m is predicted, which overcomes the observed limits met when using interrogation methods specifically developed for wireless SAW sensors, and could partly comply with the above-mentioned applications. Although quite optimistic, this estimate is consistent with the signal to noise ratio observed during an experimental demonstration of the interrogation of a delay line buried at a depth of 5 m in snow.
NASA Astrophysics Data System (ADS)
Chen, Kyle Dakai
Since the market for semiconductor products has become more lucrative and competitive, research into improving yields for semiconductor fabrication lines has lately received a tremendous amount of attention. One of the most critical tasks in achieving such yield improvements is to plan the in-line inspection sampling efficiently so that any potential yield problems can be detected early and eliminated quickly. We formulate a multi-stage inspection planning model based on configurations in actual semiconductor fabrication lines, specifically taking into account both the capacity constraint and the congestion effects at the inspection station. We propose a new mixed First-Come-First-Serve (FCFS) and Last-Come-First-Serve (LCFS) discipline for serving the inspection samples to expedite the detection of potential yield problems. Employing this mixed FCFS and LCFS discipline, we derive approximate expressions for the queueing delays in yield problem detection time and develop near-optimal algorithms to obtain the inspection logistics planning policies. We also investigate the queueing performance with this mixed type of service discipline under different assumptions and configurations. In addition, we conduct numerical tests and generate managerial insights based on input data from actual semiconductor fabrication lines. To the best of our knowledge, this research is novel in developing, for the first time in the literature, near-optimal results for inspection logistics planning in multi-stage production systems with congestion effects explicitly considered.
NASA Astrophysics Data System (ADS)
Hmood, Jassim K.; Harun, Sulaiman W.
2018-05-01
A new approach for realizing a wideband optical frequency comb (OFC) generator based on driving cascaded modulators by a Gaussian-shaped waveform, is proposed and numerically demonstrated. The setup includes N-cascaded MZMs, a single Gaussian-shaped waveform generator, and N-1 electrical time delayer. The first MZM is driven directly by a Gaussian-shaped waveform, while delayed replicas of the Gaussian-shaped waveform drive the other MZMs. An analytical model that describes the proposed OFC generator is provided to study the effect of number and chirp factor of cascaded MZM as well as pulse width on output spectrum. Optical frequency combs at frequency spacing of 1 GHz are generated by applying Gaussian-shaped waveform at pulse widths ranging from 200 to 400 ps. Our results reveal that, the number of comb lines is inversely proportional to the pulse width and directly proportional to both number and chirp factor of cascaded MZMs. At pulse width of 200 ps and chirp factor of 4, 67 frequency lines can be measured at output spectrum of two-cascaded MZMs setup. Whereas, increasing the number of cascaded stages to 3, 4, and 5, the optical spectra counts 89, 109 and 123 frequency lines; respectively. When the delay time is optimized, 61 comb lines can be achieved with power fluctuations of less than 1 dB for five-cascaded MZMs setup.
Takamuku, Shinya; Gomi, Hiroaki
2015-01-01
How our central nervous system (CNS) learns and exploits relationships between force and motion is a fundamental issue in computational neuroscience. While several lines of evidence have suggested that the CNS predicts motion states and signals from motor commands for control and perception (forward dynamics), it remains controversial whether it also performs the ‘inverse’ computation, i.e. the estimation of force from motion (inverse dynamics). Here, we show that the resistive sensation we experience while moving a delayed cursor, perceived purely from the change in visual motion, provides evidence of the inverse computation. To clearly specify the computational process underlying the sensation, we systematically varied the visual feedback and examined its effect on the strength of the sensation. In contrast to the prevailing theory that sensory prediction errors modulate our perception, the sensation did not correlate with errors in cursor motion due to the delay. Instead, it correlated with the amount of exposure to the forward acceleration of the cursor. This indicates that the delayed cursor is interpreted as a mechanical load, and the sensation represents its visually implied reaction force. Namely, the CNS automatically computes inverse dynamics, using visually detected motions, to monitor the dynamic forces involved in our actions. PMID:26156766
The effect of delays on filament oscillations and stability
NASA Astrophysics Data System (ADS)
van den Oord, G. H. J.; Schutgens, N. A. J.; Kuperus, M.
1998-11-01
We discuss the linear response of a filament to perturbations, taking the finite communication time between the filament and the photosphere into account. The finite communication time introduces delays in the system. Recently Schutgens (1997ab) investigated the solutions of the delay equation for vertical perturbations. In this paper we expand his analysis by considering also horizontal and coupled oscillations. The latter occur in asymmetric coronal fields. We also discuss the effect of Alfven wave emission on filament oscillations and show that wave emission is important for stabilizing filaments. We introduce a fairly straightforward method to study the solutions of delay equations as a function of the filament-photosphere communication time. A solution can be described by a linear combination of damped harmonic oscillations each characterized by a frequency, a damping/growth time and, accordingly, a quality factor. As a secondary result of our analysis we show that, within the context of line current models, Kippenhahn/Schlüter-type filament equilibria can never be stable in the horizontal and the vertical direction at the same time but we also demonstrate that Kuperus/Raadu-type equilibria can account for both an inverse or a normal polarity signature. The diagnostic value of our analysis for determining, e.g., the filament current from observations of oscillating filaments is discussed.
NASA Astrophysics Data System (ADS)
Wang, Yonggang; Liu, Chong
2016-10-01
The common solution for a field programmable gate array (FPGA)-based time-to-digital converter (TDC) is constructing a tapped delay line (TDL) for time interpolation to yield a sub-clock time resolution. The granularity and uniformity of the delay elements of TDL determine the TDC time resolution. In this paper, we propose a dual-sampling TDL architecture and a bin decimation method that could make the delay elements as small and uniform as possible, so that the implemented TDCs can achieve a high time resolution beyond the intrinsic cell delay. Two identical full hardware-based TDCs were implemented in a Xilinx UltraScale FPGA for performance evaluation. For fixed time intervals in the range from 0 to 440 ns, the average time-interval RMS resolution is measured by the two TDCs with 4.2 ps, thus the timestamp resolution of single TDC is derived as 2.97 ps. The maximum hit rate of the TDC is as high as half the system clock rate of FPGA, namely 250 MHz in our demo prototype. Because the conventional online bin-by-bin calibration is not needed, the implementation of the proposed TDC is straightforward and relatively resource-saving.
Chieffi, Sergio; Messina, Giovanni; Messina, Antonietta; Villano, Ines; Monda, Vincenzo; Ambra, Ferdinando Ivano; Garofalo, Elisabetta; Romano, Felice; Mollica, Maria Pina; Monda, Marcellino; Iavarone, Alessandro
2017-01-01
Previous studies suggested that the occipitoparietal stream orients attention toward the near/lower space and is involved in immediate reaching, whereas the occipitotemporal stream orients attention toward the far/upper space and is involved in delayed reaching. In the present study, we investigated the role of the occipitotemporal stream in attention orienting and delayed reaching in a patient (GP) with bilateral damage to the occipitoparietal areas and optic ataxia. GP and healthy controls took part in three experiments. In the experiment 1, the participants bisected lines oriented along radial, vertical, and horizontal axes. GP bisected radial lines farther, and vertical lines more above, than the controls, consistent with an attentional bias toward the far/upper space and near/lower space neglect. The experiment 2 consisted of two tasks: (1) an immediate reaching task, in which GP reached target locations under visual control and (2) a delayed visual reaching task, in which GP and controls were asked to reach remembered target locations visually presented. We measured constant and variable distance and direction errors. In immediate reaching task, GP accurately reached target locations. In delayed reaching task, GP overshot remembered target locations, whereas the controls undershot them. Furthermore, variable errors were greater in GP than in the controls. In the experiment 3, GP and controls performed a delayed proprioceptive reaching task. Constant reaching errors did not differ between GP and the controls. However, variable direction errors were greater in GP than in the controls. We suggest that the occipitoparietal damage, and the relatively intact occipitotemporal region, produced in GP an attentional orienting bias toward the far/upper space (experiment 1). In turns, the attentional bias selectively shifted toward the far space remembered visual (experiment 2), but not proprioceptive (experiment 3), target locations. As a whole, these findings further support the hypothesis of an involvement of the occipitotemporal stream in delayed reaching. Furthermore, the observation that in both delayed reaching tasks the variable errors were greater in GP than in the controls suggested that in optic ataxia is present not only a visuo- but also a proprioceptivo-motor integration deficit. PMID:28620345
The Sojourn Time in a Three Node, Acyclic, Jackson Queueing Network.
1982-01-27
Effect of Intermediate Storage on Production Lines with Dependent Machines, Robert D. Foley and Petcharat Chansaenwilai 8015 Some Conditions for the...Queues, Robert D. Foley 8105 Reversibility of Production Lines with Dependent Machines, Petcharat Chansaenwilai 1 8106 Queues with Delayed Feedback, Robert
Overload protection for switching regulators
NASA Technical Reports Server (NTRS)
Lachochi, E.
1980-01-01
Circuit protects all output lines of switching regulator against overloads without requiring current sensors on every line. If overload is sensed, device short circuits bias on switching transistor so that power is rapidly cut off from loads. Circuit also includes delay network to inhibit erroneous operation during startup.
Ultra-Wide Band Non-reciprocity through Sequentially-Switched Delay Lines.
Biedka, Mathew M; Zhu, Rui; Xu, Qiang Mark; Wang, Yuanxun Ethan
2017-01-06
Achieving non-reciprocity through unconventional methods without the use of magnetic material has recently become a subject of great interest. Towards this goal a time switching strategy known as the Sequentially-Switched Delay Line (SSDL) is proposed. The essential SSDL configuration consists of six transmission lines of equal length, along with five switches. Each switch is turned on and off sequentially to distribute and route the propagating electromagnetic wave, allowing for simultaneous transmission and receiving of signals through the device. Preliminary experimental results with commercial off the shelf parts are presented which demonstrated non-reciprocal behavior with greater than 40 dB isolation from 200 KHz to 200 MHz. The theory and experimental results demonstrated that the SSDL concept may lead to future on-chip circulators over multi-octaves of frequency.
Ultra-Wide Band Non-reciprocity through Sequentially-Switched Delay Lines
Biedka, Mathew M.; Zhu, Rui; Xu, Qiang Mark; Wang, Yuanxun Ethan
2017-01-01
Achieving non-reciprocity through unconventional methods without the use of magnetic material has recently become a subject of great interest. Towards this goal a time switching strategy known as the Sequentially-Switched Delay Line (SSDL) is proposed. The essential SSDL configuration consists of six transmission lines of equal length, along with five switches. Each switch is turned on and off sequentially to distribute and route the propagating electromagnetic wave, allowing for simultaneous transmission and receiving of signals through the device. Preliminary experimental results with commercial off the shelf parts are presented which demonstrated non-reciprocal behavior with greater than 40 dB isolation from 200 KHz to 200 MHz. The theory and experimental results demonstrated that the SSDL concept may lead to future on-chip circulators over multi-octaves of frequency. PMID:28059132
DFB laser - External modulator fiber optic delay line for radar applications
NASA Astrophysics Data System (ADS)
Newberg, I. L.; Gee, C. M.; Thurmond, G. D.; Yen, H. W.
1989-09-01
A new application of a long fiber-optic delay line as a radar repeater in a radar test set is described. The experimental 31.6-kilometer fiber-optic link includes an external modulator operating with a distributed-feedback laser and low-loss single-mode fiber matched to the laser wavelength to obtain low dispersion for achieving large bandwidth-length performance. The successful tests, in which pulse compression peak sidelobe measurements are used to confirm the link RF phase linearity and SNR performance, show that fiber-optic links can meet the stringent phase and noise requirements of modern radars at high microwave frequencies.
Displacement sensors using soft magnetostrictive alloys
NASA Astrophysics Data System (ADS)
Hristoforou, E.; Reilly, R. E.
1994-09-01
We report results on the response of a family of displacement sensors, which are based on the magentostrictive delay line (MDL) technique, using current conductors orthogonal to the MDL. Such sensing technique is based on the change of the magnetic circuit at the acoustic stress point of origin due to the displacement of a soft magnetic material above it. Integrated arrays of sensors can be obtained due to the acoustic delay line technique and they can be used as tactile arrays, digitizers or devices for medical applications (gait analysis etc.), while absence of hysteresis and low cost of manufacturing make them competent in this sector of sensor market.
It takes two-coincidence coding within the dual olfactory pathway of the honeybee.
Brill, Martin F; Meyer, Anneke; Rössler, Wolfgang
2015-01-01
To rapidly process biologically relevant stimuli, sensory systems have developed a broad variety of coding mechanisms like parallel processing and coincidence detection. Parallel processing (e.g., in the visual system), increases both computational capacity and processing speed by simultaneously coding different aspects of the same stimulus. Coincidence detection is an efficient way to integrate information from different sources. Coincidence has been shown to promote associative learning and memory or stimulus feature detection (e.g., in auditory delay lines). Within the dual olfactory pathway of the honeybee both of these mechanisms might be implemented by uniglomerular projection neurons (PNs) that transfer information from the primary olfactory centers, the antennal lobe (AL), to a multimodal integration center, the mushroom body (MB). PNs from anatomically distinct tracts respond to the same stimulus space, but have different physiological properties, characteristics that are prerequisites for parallel processing of different stimulus aspects. However, the PN pathways also display mirror-imaged like anatomical trajectories that resemble neuronal coincidence detectors as known from auditory delay lines. To investigate temporal processing of olfactory information, we recorded PN odor responses simultaneously from both tracts and measured coincident activity of PNs within and between tracts. Our results show that coincidence levels are different within each of the two tracts. Coincidence also occurs between tracts, but to a minor extent compared to coincidence within tracts. Taken together our findings support the relevance of spike timing in coding of olfactory information (temporal code).
A prototype gas exchange monitor for exercise stress testing aboard NASA Space Station
NASA Technical Reports Server (NTRS)
Orr, Joseph A.; Westenskow, Dwayne R.; Bauer, Anne
1989-01-01
This paper describes an easy-to-use monitor developed to track the weightlessness deconditioning aboard the NASA Space Station, together with the results of testing of a prototype instrument. The monitor measures the O2 uptake and CO2 production, and calculates the maximum O2 uptake and anaerobic threshold during an exercise stress test. The system uses two flowmeters in series to achieve a completely automatic calibration, and uses breath-by-breath compensation for sample line-transport delay. The monitor was evaluated using two laboratory methods and was shown to be accurate. The system's block diagram and the bench test setup diagram are included.
Geoengineering Marine Ice Sheets
NASA Astrophysics Data System (ADS)
Wolovick, M.
2017-12-01
Mass loss from Greenland and Antarctica is highly sensitive to the presence of warm ocean water that drives melting at the grounding line. Rapid melting near the grounding line causes ice shelf thinning, loss of buttressing, flow acceleration, grounding line retreat, and ultimately mass loss and sea-level rise. If the grounding line enters a section of overdeepened bed the ice sheet may even enter a runaway collapse via the marine ice sheet instability. The warm water that triggers this process resides offshore at depth and accesses the grounding line through deep troughs in the continental shelf. In Greenland, warm water transport is further constricted through narrow fjords. Here, I propose blocking warm water transport through these choke points with an artificial sill. Using a simple width- and depth-averaged model of ice stream flow coupled to a buoyant-plume model of ocean melting, I find that grounding line retreat and sea level rise can be delayed or reversed for hundreds of years if warm water is prevented from accessing the grounding line at depth. Blocking of warm water from the sub-ice cavity causes ice shelf thickening, increased buttressing, and grounding line readvance. The increase in buttressing is greatly magnified if the thickened ice shelf regrounds on a bathymetric high or on the artificial sill itself. In some experiments for Thwaites Glacier the grounding line is able to recover from a severely retreated state over 100 km behind its present-day position. Such a dramatic recovery demonstrates that it is possible, at least in principle, to stop and reverse an ongoing marine ice sheet collapse. If the ice shelf regrounds on the artificial sill itself, erosion of the sill beneath the grounded ice could reduce the effectiveness of the intervention. However, experiments including sill erosion suggest that even a very weak sill (1 kPa) could delay a collapse for centuries. The scale of the artificial sills in Greenlandic fjords is comparable to existing large public works, while in Antarctica they are one to two orders of magnitude larger. However, this is still small in comparison to the global disruption that would be caused by a collapse of West Antarctica. Marine-terminating ice streams are high-leverage points in the climate system, where global impacts can be achieved through local intervention.
NASA Technical Reports Server (NTRS)
Szatkowski, G. P.
1983-01-01
A computer simulation system has been developed for the Space Shuttle's advanced Centaur liquid fuel booster rocket, in order to conduct systems safety verification and flight operations training. This simulation utility is designed to analyze functional system behavior by integrating control avionics with mechanical and fluid elements, and is able to emulate any system operation, from simple relay logic to complex VLSI components, with wire-by-wire detail. A novel graphics data entry system offers a pseudo-wire wrap data base that can be easily updated. Visual subsystem operations can be selected and displayed in color on a six-monitor graphics processor. System timing and fault verification analyses are conducted by injecting component fault modes and min/max timing delays, and then observing system operation through a red line monitor.
Tomankova, Katerina; Polakova, Katerina; Pizova, Klara; Binder, Svatopluk; Havrdova, Marketa; Kolarova, Mary; Kriegova, Eva; Zapletalova, Jana; Malina, Lukas; Horakova, Jana; Malohlava, Jakub; Kolokithas-Ntoukas, Argiris; Bakandritsos, Aristides; Kolarova, Hana; Zboril, Radek
2015-01-01
One of the promising strategies for improvement of cancer treatment is based on magnetic drug delivery systems, thus avoiding side effects of standard chemotherapies. Superparamagnetic iron oxide (SPIO) nanoparticles have ideal properties to become a targeted magnetic drug delivery contrast probes, named theranostics. We worked with SPIO condensed colloidal nanocrystal clusters (MagAlg) prepared through a new soft biomineralization route in the presence of alginate as the polymeric shell and loaded with doxorubicin (DOX). The aim of this work was to study the in vitro cytotoxicity of these new MagAlg–DOX systems on mouse fibroblast and breast carcinoma cell lines. For proper analysis and understanding of cell behavior after administration of MagAlg–DOX compared with free DOX, a complex set of in vitro tests, including production of reactive oxygen species, comet assay, cell cycle determination, gene expression, and cellular uptake, were utilized. It was found that the cytotoxic effect of MagAlg–DOX system is delayed compared to free DOX in both cell lines. This was attributed to the different mechanism of internalization of DOX and MagAlg–DOX into the cells, together with the fact that the drug is strongly bound on the drug nanocarriers. We discovered that nanoparticles can attenuate or even inhibit the effect of DOX, particularly in the tumor MCF7 cell line. This is a first comprehensive study on the cytotoxic effect of DOX-loaded SPIO compared with free DOX on healthy and cancer cell lines, as well as on the induced changes in gene expression. PMID:25673990
Numerical Bifurcation Analysis of Delayed Recycle Stream in a Continuously Stirred Tank Reactor
NASA Astrophysics Data System (ADS)
Gangadhar, Nalwala Rohitbabu; Balasubramanian, Periyasamy
2010-10-01
In this paper, we present the stability analysis of delay differential equations which arise as a result of transportation lag in the CSTR-mechanical separator recycle system. A first order irreversible elementary reaction is considered to model the system and is governed by the delay differential equations. The DDE-BIFTOOL software package is used to analyze the stability of the delay system. The present analysis reveals that the system exhibits delay independent stability for isothermal operation of the CSTR. In the absence of delay, the system is dynamically unstable for non-isothermal operation of the CSTR, and as a result of delay, the system exhibits delay dependent stability.
Design of on-line system for measuring and tracking time of assembly
NASA Astrophysics Data System (ADS)
Senderská, Katarína; Mareš, Albert; Evin, Emil
2016-04-01
Manual assembly performed at assembly workstations nowadays still has a unique place in different kinds of production. To increase the productivity and quality of manual assembly it is necessary to analyse the existing workplaces and find ways to improve and streamline work done at these workplaces. The article deals with the design of a model for on-line analysis of a manual assembly process. The proposed model is based on the use of sensors or the so-called button-box and the use of software for recording and evaluating data. Based on the obtained data it is then possible to evaluate the time characteristics of the assembly process, aswell as to find sources of delays and mistakes and then take appropriate action to correct them.
Non-line-of-sight single-scatter propagation model for noncoplanar geometries.
Elshimy, Mohamed A; Hranilovic, Steve
2011-03-01
In this paper, a geometrical propagation model is developed that generalizes the classical single-scatter model under the assumption of first-order scattering and non-line-of-sight (NLOS) communication. The generalized model considers the case of a noncoplanar geometry, where it overcomes the restriction that the transmitter and the receiver cone axes lie in the same plane. To verify the model, a Monte Carlo (MC) radiative transfer model based on a photon transport algorithm is constructed. Numerical examples for a wavelength of 266 nm are illustrated, which corresponds to a solar-blind NLOS UV communication system. A comparison of the temporal responses of the generalized model and the MC simulation results shows close agreement. Path loss and delay spread are also shown for different pointing directions.
NASA Astrophysics Data System (ADS)
Caliendo, Cinzia
2006-09-01
The relative humidity (RH) sensing behavior of a polymeric film was investigated by means of polymer coated surface acoustic wave (SAW) delay lines implemented on single crystal piezoelectric substrates, such as quartz and LiNbO3, and on thin piezoelectric polycrystalline films, such as ZnO and AlN, on Si and GaAs. The same SAW delay line configuration was implemented on each substrate and the obtained devices' operating frequency was in the range of 105-156MHz, depending on the type of the substrate, on its crystallographic orientation, and on the SAW propagation direction. The surface of each SAW device was covered by the same type RH sensitive film of the same thickness and the RH sensitivity of each polymer coated substrate, i.e., the SAW relative phase velocity shift per RH unit changes, was investigated in the 0%—80% RH range. The perturbational approach was used to relate the SAW sensor velocity response to the RH induced changes in the physical parameters of the sensitive polymer film: the incremental change in the mass density and shear modulus of the polymer film per unit RH change were estimated. The shift of the bare SAW delay lines operating frequency induced by the presence of the polymer film, at RH =0% and at T =-10°C, allowed the experimental estimation of the mass sensitivity values of each substrate. These values were in good accordance with those reported in the literature and with those theoretically evaluated by exact numerical calculation. The shift of the bare SAW delay lines propagation loss induced by the polymer coating of the device surface, at RH =0% and at ambient temperature, allowed the experimental estimation of the elastic sensitivity of each substrate. These values were found in good accordance with those available from the literature. The temperature coefficient of delay and the electromechanical coupling coefficient of the bare substrates were also estimated. The membrane sensitivity to ethanol, methanol and isopropylic alcohol was tested by means of a high-frequency (670MHz) high-sensitivity Si /AlN resonator sensor.
NASA Astrophysics Data System (ADS)
Seraji, Faramarz E.
2009-03-01
In practice, dynamic behavior of fiber-optic ring resonator (FORR) appears as a detrimental factor to influence the transmission response of the FORR. This paper presents dynamic response analysis of the FORR by considering phase modulation of the FORR loop and sinewave modulation of input signal applied to the FORR from a laser diode. The analysis investigates the influences of modulation frequency and amplitude modulation index of laser diode, loop delay time of the FORR, phase angle between FM and AM response of laser diode, and laser diode line-width on dynamic response of the FORR. The analysis shows that the transient response of the FORR strongly depends on the product of modulation frequency and loop delay time, coupling and transmission coefficients of the FORR. The analyses presented here may have applications in optical systems employing an FORR with a laser diode source.
Performance analysis of dynamic time-slot allocation system
NASA Astrophysics Data System (ADS)
Kong, Hongwei; Ruan, Fang; Feng, Chongxi
2001-10-01
Multi-service Access on the narrow-band DDN (Digital Data Network) leased lines to use the bandwidth more efficiently and reduce the cost has attracted much interest. In this paper, one novel multi-service multiplexing scheme based on DTSA (Dynamic Time-Slot Allocation) is given. This scheme can guarantee the QoS of the multiplexed services such as FAX, Voice and data and adapt to different link rates (64kb/s, 128kb/s, 256kb/s), A model is given in this paper to analyze the data behavior under this scheme. The simulation result and the model result have shown that the QoS guarantee to voice and FAX doesn't compromise the QoS of data service much in the meaning of delay and delay variance when the data load is not too high. The simulation result agrees with the model well when data load is not too high.
SALT long-slit spectroscopy of CTS C30.10: two-component Mg II line
NASA Astrophysics Data System (ADS)
Modzelewska, J.; Czerny, B.; Hryniewicz, K.; Bilicki, M.; Krupa, M.; Świȩtoń, A.; Pych, W.; Udalski, A.; Adhikari, T. P.; Petrogalli, F.
2014-10-01
Context. Quasars can be used as a complementary tool to SN Ia to probe the distribution of dark energy in the Universe by measuring the time delay of the emission line with respect to the continuum. The understanding of the Mg II emission line structure is important for cosmological application and for the black hole mass measurements of intermediate redshift quasars. Aims: Knowing the shape of Mg II line and its variability allows for identifying which part of the line should be used to measure the time delay and the black hole mass. We thus aim at determining the structure and the variability of the Mg II line, as well as the underlying Fe II pseudo-continuum. Methods: We performed five spectroscopic observations of a quasar CTS C30.10 (z = 0.9000) with the SALT telescope between December 2012 and March 2014, and we studied the variations in the spectral shape in the 2700 Å-2900 Å rest frame. Results: We show that the Mg II line in this source consists of two kinematic components, which makes the source representative of type B quasars. Both components were modeled well with a Lorentzian shape, and they vary in a similar way. The Fe II contribution seems to be related only to the first (blue) Mg II component. Broad band spectral fitting instead favor the use of the whole line profile. The contribution of the narrow line region to Mg II is very low, below 2%. The Mg II variability is lower than the variability of the continuum, which is consistent with the simple reprocessing scenario. The variability level of CTS C30.10 and the measurement accuracy of the line and continuum is high enough to expect that further monitoring will allow the time delay between the Mg II line and continuum to be measured. Based on observations made with the Southern African Large Telescope (SALT) under program 2012-2-POL-003 and 2013-1-POL-RSA-002 (PI: B. Czerny).Spectra shown in Figs. 3 and 4 are only available in electronic form at the CDS via anonymous ftp to http://cdsarc.u-strasbg.fr (ftp://130.79.128.5) or via http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/570/A53Table 1 is available in electronic form at http://www.aanda.org
Magnetically excited flexural plate wave apparatus
Martin, Stephen J.; Butler, Michael A.; Frye, Gregory C.; Smith, James H.
1998-01-01
A non-piezoelectric flexural plate wave apparatus having meander-line transducers mounted on a non-piezoelectric membrane. A static magnetic field is directed perpendicularly to the conductive legs of the transducers in the plane of the membrane. Single-port, two-port, resonant, non-resonant, eigenmode, and delay-line modes may be employed.
128 Gb/s TWDM PON system using dispersion-supported transmission method
NASA Astrophysics Data System (ADS)
Bindhaiq, Salem; Zulkifli, Nadiatulhuda; Supa'at, Abusahmah M.; Idrus, Sevia M.; Salleh, M. S.
2017-11-01
Time and wavelength division multiplexed passive optical network (TWDM-PON) trend is considered as the most extraordinary trend of the next generation solution to accommodate exponential traffic growth for converged new services. In this paper, we briefly review recent progress on TWDM-PON system through the use of low cost directly modulated lasers (DMLs) transmission for various line rate transmissions to date. Furthermore, through simulation, we propose and evaluate a cost effective way to upgrade TWDM-PON up to a symmetric capacity of 128 Gb/s using fiber Bragg gratings (FBGs) in optical line terminal (OLT) as a paramount dispersion manager in high speed light-wave systems in both upstream and downstream directions. A low cost and potential chirpless directed modulated grating laser (DMGL) is employed for downstream link and DML with a single delay-interferometer (DI) is employed for upstream link. After illustrating the demonstrated system architecture and configuration, we present the results and analysis to prove the system feasibility. The results show that a successful transmission is achieved over 40 km single mode fiber with a power budget of 33.7 dB, which could support 1:256 splitting ratio.
NASA Astrophysics Data System (ADS)
Gondal, M. A.; Dastageer, M. A.; Al-Adel, F. F.; Naqvi, A. A.; Habibullah, Y. B.
2015-12-01
A sensitive laser induced breakdown spectroscopic system was developed and optimized for using it as a sensor for the detection of trace levels of lead and chromium present in the cosmetic eyeliner (kohl) of different price ranges (brands) available in the local market. Kohl is widely used in developing countries for babies as well adults for beautification as well eyes protection. The atomic transition lines at 405.7 nm and 425.4 nm were used as the marker lines for the detection of lead and chromium respectively. The detection system was optimized by finding the appropriate gate delay between the laser excitation and the data acquisition system and also by achieving optically thin plasma near the target by establishing the local thermodynamic equilibrium condition. The detection system was calibrated for these two hazardous elements and the kohl samples under investigation showed 8-15 ppm by mass of lead and 4-9 ppm by mass of Chromium, which are higher than the safe permissible levels of these elements. The limits of detection of the LIBS system for lead and chromium were found to be 1 and 2 ppm respectively.
Microwave radiometry as a tool to calibrate tropospheric water-vapor delay
NASA Technical Reports Server (NTRS)
Resch, G. M.; Claflin, E. S.
1980-01-01
Microwave radiometers were used to measure the emission line due to the water vapor molecules of atmospheric emission. Four separate field tests were completed which compared radiometers to other techniques which measure water vapor. It is shown that water vapor induced delay can be estimated with an accuracy of plus or minus 2 cm for elevation angles above 17 degrees.
NASA Astrophysics Data System (ADS)
Cui, Ke; Ren, Zhongjie; Li, Xiangyu; Liu, Zongkai; Zhu, Rihong
2017-01-01
Time-to-digital converters (TDCs) using dedicated carry chains of field programmable gate arrays (FPGAs) are usually organized in tapped-delay-line type which are intensively researched in recent years. However this method incurs poor differential nonlinearity (DNL) which arises from the inherent uneven bin granularity. This paper proposes a TDC architecture which utilizes the carry chains in a quite different manner in order to alleviate this long-standing problem. Two independent carry chains working as the delay lines for the fine time interpolation are organized in a ring-oscillator-based Vernier style and the time difference between them is finely adjusted by assigning different number of basic delay cells. A specific design flow is described to obtain the desired delay difference. The TDC was implemented on a Stratix III FPGA. Test results show that the obtained resolution is 31 ps and the DNL\\INL is in the range of (-0.080 LSB, 0.073 LSB)(-0.087 LSB, 0.091 LSB). This demonstrates that the proposed architecture greatly improves linearity compared to previous techniques. Additionally the resource cost is rather low which uses only 319 LUTs and 104 registers per TDC channel.
1992-08-01
history trace of input u(t). (b) A common network struc- 1 ture makes use of the feedforward tapped delay line. For this structure the memory depth D...theories and analyses that will be used world- wide for a long time to come. The reason for this contribution has generally been the government’s need to...that emulate the neural reasoning behavior of biological neural systems (e.g. the human brain). As such, they are loosely based on biological neural
The Technical Problems of Anti-theft Diagnostics in a Traction Network
NASA Astrophysics Data System (ADS)
Mikulski, Jerzy; Młynczak, Jakub
2012-02-01
The paper presents an analysis of traction lines theft in the Katowice division of the Railroad Development Company (Zakład Linii Kolejowych - ZLK) as well as the principles for the anti-theft protection system, currently in development. The problem of theft is a very important issue concerning the safety of rail transportation. It is also a significant economic problem, as the cost of recreating a stolen network is very high. Moreover, the Administrator of the infrastructure bears the cost of compensation for any delays in train schedules.
1979-12-13
I III| I IIG since t - T < T = t - L (W - i) _ t is a point of stationary phase. -2a o 1 Eq. (4.86) shows that the output of the chirp filter is the...Parametric Interactions in Delay-Line Devices", IEEE Transactions on Microwave Theory and Techniques, vol. MTT-21, no. 4, April 1973, pp. 2414-257...443-476. Martin, T. A., "The IMCON Pulse Compression Filter and its Applications", IE3 Transactions on Microwave Theory and Techniques, vol. 21
Pattern classification using charge transfer devices
NASA Technical Reports Server (NTRS)
1980-01-01
The feasibility of using charge transfer devices in the classification of multispectral imagery was investigated by evaluating particular devices to determine their suitability in matrix multiplication subsystem of a pattern classifier and by designing a protype of such a system. Particular attention was given to analog-analog correlator devices which consist of two tapped delay lines, chip multipliers, and a summed output. The design for the classifier and a printed circuit layout for the analog boards were completed and the boards were fabricated. A test j:g for the board was built and checkout was begun.
NASA Technical Reports Server (NTRS)
Romanofsky, Robert R.
2006-01-01
We have developed relatively broadband K- and Ka-band phase shifters using synthetic (slow-wave) transmission lines employing coupled microstripline "varactors". The tunable coupled microstripline circuits are based on laser ablated BaSrTiO films on lanthanum aluminate substrates. A model and design criteria for these novel circuits will be presented, along with measured performance including anomalous phase delay characteristics. The critical role of phase shifter loss and transient response in reflectarray antennas will be emphasized.
Perspectives for on-line analysis of bauxite by neutron irradiation
NASA Astrophysics Data System (ADS)
Beurton, Gabriel; Ledru, Bertrand; Letourneur, Philippe
1995-03-01
The interest in bauxite as a major source of alumina results in a strong demand for on-line instrumentation suitable for sorting, blending, and processing operations at the bauxite mine and for monitoring instrumentation in the Bayer process. The results of laboratory experiments based on neutron interactions with bauxite are described. The technique was chosen in order to overcome the problem of spatial heterogeneity in bulk mineral analysis. The evaluated elements contributed to approximately 99.5% of the sample weight. In addition, the measurements provide valuable information on physical parameters such as density, hygrometry, and material flow. Using a pulsed generator, the analysis system offers potential for on-line measurements (borehole logging or conveyor belt). An overall description of the experimental set-up is given. The experimental data include measurements of natural radioactivity, delayed radioactivity induced by activation, and prompt gamma rays following neutron reaction. In situ applications of neutron interactions provide continuous analysis and produce results which are more statistically significant. The key factors contributing to advances in industrial applications are the development of high count rate gamma spectroscopy and computational tools to design measurement systems and interpret their results.
Displacement sensors using soft magnetostrictive alloys
DOE Office of Scientific and Technical Information (OSTI.GOV)
Hristoforou, E.; Reilly, R.E.
1994-09-01
The authors report results on the response of a family of displacement sensors, which are based on the magnetostrictive delay line (MDL) technique, using current conductor orthogonal to the MDL. Such sensing technique is based on the change of the magnetic circuit and the acoustic stress point of origin due to the displacement of a soft magnetic material above it. Integrated arrays of sensors can be obtained due to the acoustic delay line technique and they can be used as tactile arrays, digitizers or devices for medical application (gait analysis etc.), while absence of hysteresis and low cost of manufacturingmore » make them competent in this sector of sensor market.« less
NASA Astrophysics Data System (ADS)
Lee, Eunjoo; Kim, Byoung Yoon
2017-12-01
We propose a new scheme for an actively mode-locked wavelength-swept fiber laser that produces a train of discretely wavelength-stepped pulses from a short fiber cavity. Pulses with different wavelengths are split and combined by standard wavelength division multiplexers with fiber delay lines. As a proof of concept, we demonstrate a laser using an erbium doped fiber amplifier and commercially available wavelength-division multiplexers with wavelength spacing of 0.8 nm. The results show simultaneous mode-locking at three different wavelengths. Laser output parameters in time domain, optical and radio frequency spectral domain, and the noise characteristics are presented. Suggestions for the improved design are discussed.
Semwal, Vimal Kumar; Singh, Bhupinder; Khanna-Chopra, Renu
2014-04-01
Reproductive sinks regulate monocarpic senescence in crop plants. Monocarpic senescence was studied in wheat fertile (cv. HW 2041) and its isonuclear cytoplasmic male sterile (CMS) line. CMS plants exhibited slower rate of senescence accompanied by longer green leaf area duration and slower deceleration in chlorophyll, protein content, PN and rubisco content coupled with lower protease activities than fertile (F) plants. CMS plants also exhibited lower ROS levels and less membrane damage than F plants. CMS plants maintained better antioxidant defense, less oxidative damage in chloroplast and higher transcript levels of both rbcL and rbcS genes during senescence than F plants. F plants exhibited early induction and higher expression of SAGs like serine and cysteine proteases, glutamine synthetases GS1 and GS2, WRKY53 transcription factor and decline in transcript levels of CAT1 and CAT2 genes than CMS plants. Hence, using genetically fertile and its CMS line of wheat it is confirmed that delayed senescence in the absence of reproductive sinks is linked with slower protein oxidation, rubisco degradation and delayed activation of SAGs. Better antioxidant defense in chloroplasts at later stages of senescence was able to mitigate the deleterious effects of ROS in CMS plants. We propose that delayed increase in ROS in cytoplasmic male sterile wheat plants resulted in delayed activation of WRKY53, SAGs and the associated biochemical changes than fertile plants.
An autonomous recovery mechanism against optical distribution network failures in EPON
NASA Astrophysics Data System (ADS)
Liem, Andrew Tanny; Hwang, I.-Shyan; Nikoukar, AliAkbar
2014-10-01
Ethernet Passive Optical Network (EPON) is chosen for servicing diverse applications with higher bandwidth and Quality-of-Service (QoS), starting from Fiber-To-The-Home (FTTH), FTTB (business/building) and FTTO (office). Typically, a single OLT can provide services to both residential and business customers on the same Optical Line Terminal (OLT) port; thus, any failures in the system will cause a great loss for both network operators and customers. Network operators are looking for low-cost and high service availability mechanisms that focus on the failures that occur within the drop fiber section because the majority of faults are in this particular section. Therefore, in this paper, we propose an autonomous recovery mechanism that provides protection and recovery against Drop Distribution Fiber (DDF) link faults or transceiver failure at the ONU(s) in EPON systems. In the proposed mechanism, the ONU can automatically detect any signal anomalies in the physical layer or transceiver failure, switching the working line to the protection line and sending the critical event alarm to OLT via its neighbor. Each ONU has a protection line, which is connected to the nearest neighbor ONU, and therefore, when failure occurs, the ONU can still transmit and receive data via the neighbor ONU. Lastly, the Fault Dynamic Bandwidth Allocation for recovery mechanism is presented. Simulation results show that our proposed autonomous recovery mechanism is able to maintain the overall QoS performance in terms of mean packet delay, system throughput, packet loss and EF jitter.
NASA Astrophysics Data System (ADS)
Zhao, Wenyu; Zhang, Haiyi; Ji, Yuefeng; Xu, Daxiong
2004-05-01
Based on the proposed polarization mode dispersion (PMD) compensation simulation model and statistical analysis method (Monte-Carlo), the critical parameters initialization of two typical optical domain PMD compensators, which include optical PMD method with fixed compensation differential group delay (DGD) and that with variable compensation DGD, are detailedly investigated by numerical method. In the simulation, the line PMD values are chosen as 3ps, 4ps and 5ps and run samples are set to 1000 in order to achieve statistical evaluation for PMD compensated systems, respectively. The simulation results show that for the PMD value pre-known systems, the value of the fixed DGD compensator should be set to 1.5~1.6 times of line PMD value in order to reach the optimum performance, but for the second kind of PMD compensator, the DGD range of lower limit should be 1.5~1.6 times of line PMD provided that of upper limit is set to 3 times of line PMD, if no effective ways are chosen to resolve the problem of local minimum in optimum process. Another conclusion can be drawn from the simulation is that, although the second PMD compensator holds higher PMD compensation performance, it will spend more feedback loops to look up the optimum DGD value in the real PMD compensation realization, and this will bring more requirements on adjustable DGD device, not only wider adjustable range, but rapid adjusting speed for real time PMD equalization.
Cytotoxic effects of ultra-diluted remedies on breast cancer cells.
Frenkel, Moshe; Mishra, Bal Mukund; Sen, Subrata; Yang, Peiying; Pawlus, Alison; Vence, Luis; Leblanc, Aimee; Cohen, Lorenzo; Banerji, Pratip; Banerji, Prasanta
2010-02-01
The use of ultra-diluted natural products in the management of disease and treatment of cancer has generated a lot of interest and controversy. We conducted an in vitro study to determine if products prescribed by a clinic in India have any effect on breast cancer cell lines. We studied four ultra-diluted remedies (Carcinosin, Phytolacca, Conium and Thuja) against two human breast adenocarcinoma cell lines (MCF-7 and MDA-MB-231) and a cell line derived from immortalized normal human mammary epithelial cells (HMLE). The remedies exerted preferential cytotoxic effects against the two breast cancer cell lines, causing cell cycle delay/arrest and apoptosis. These effects were accompanied by altered expression of the cell cycle regulatory proteins, including downregulation of phosphorylated Rb and upregulation of the CDK inhibitor p27, which were likely responsible for the cell cycle delay/arrest as well as induction of the apoptotic cascade that manifested in the activation of caspase 7 and cleavage of PARP in the treated cells. The findings demonstrate biological activity of these natural products when presented at ultra-diluted doses. Further in-depth studies with additional cell lines and animal models are warranted to explore the clinical applicability of these agents.
Switched-beam radiometer front-end network analysis
NASA Technical Reports Server (NTRS)
Trew, R. J.; Bilbro, G. L.
1994-01-01
The noise figure performance of various delay-line networks fabricated from microstrip lines with varying number of elements was investigated using a computer simulation. The effects of resistive losses in both the transmission lines and power combiners were considered. In general, it is found that an optimum number of elements exists, depending upon the resistive losses present in the network. Small resistive losses are found to have a significant degrading effect upon the noise figure performance of the array. Extreme stability in switching characteristics is necessary to minimize the nondeterministic noise of the array. For example, it is found that a 6 percent tolerance on the delay-line lengths will produce a 0.2 db uncertainty in the noise figure which translates into a 13.67 K temperature uncertainty generated by the network. If the tolerance can be held to 2 percent, the uncertainty in noise figure and noise temperature will be 0.025 db and 1.67 K, respectively. Three phase shift networks fabricated using a commercially available PIN diode switch were investigated. Loaded-line phase shifters are found to have desirable RF and noise characteristics and are attractive components for use in phased-array networks.
NASA Astrophysics Data System (ADS)
Kuo, Hung-Fei; Kao, Guan-Hsuan; Zhu, Liang-Xiu; Hung, Kuo-Shu; Lin, Yu-Hsin
2018-02-01
This study used a digital micromirror device (DMD) to produce point-array patterns and employed a self-developed optical system to define line-and-space patterns on nonplanar substrates. First, field tracing was employed to analyze the aerial images of the lithographic system, which comprised an optical system and the DMD. Multiobjective particle swarm optimization was then applied to determine the spot overlapping rate used. The objective functions were set to minimize linewidth and maximize image log slope, through which the dose of the exposure agent could be effectively controlled and the quality of the nonplanar lithography could be enhanced. Laser beams with 405-nm wavelength were employed as the light source. Silicon substrates coated with photoresist were placed on a nonplanar translation stage. The DMD was used to produce lithographic patterns, during which the parameters were analyzed and optimized. The optimal delay time-sequence combinations were used to scan images of the patterns. Finally, an exposure linewidth of less than 10 μm was successfully achieved using the nonplanar lithographic process.
NASA Astrophysics Data System (ADS)
Waters, Tim; Kashi, Amit; Proga, Daniel; Eracleous, Michael; Barth, Aaron J.; Greene, Jenny
2016-08-01
The latest analysis efforts in reverberation mapping are beginning to allow reconstruction of echo images (or velocity-delay maps) that encode information about the structure and kinematics of the broad line region (BLR) in active galactic nuclei (AGNs). Such maps can constrain sophisticated physical models for the BLR. The physical picture of the BLR is often theorized to be a photoionized wind launched from the AGN accretion disk. Previously we showed that the line-driven disk wind solution found in an earlier simulation by Proga and Kallman is virialized over a large distance from the disk. This finding implies that, according to this model, black hole masses can be reliably estimated through reverberation mapping techniques. However, predictions of echo images expected from line-driven disk winds are not available. Here, after presenting the necessary radiative transfer methodology, we carry out the first calculations of such predictions. We find that the echo images are quite similar to other virialized BLR models such as randomly orbiting clouds and thin Keplerian disks. We conduct a parameter survey exploring how echo images, line profiles, and transfer functions depend on both the inclination angle and the line opacity. We find that the line profiles are almost always single peaked, while transfer functions tend to have tails extending to large time delays. The outflow, despite being primarily equatorially directed, causes an appreciable blueshifted excess on both the echo image and line profile when seen from lower inclinations (I≲ 45^\\circ ). This effect may be observable in low ionization lines such as {{H}}β .
Delay-Line Three-Dimensional Position Sensitive Radiation Detection
NASA Astrophysics Data System (ADS)
Jeong, Manhee
High-resistivity silicon(Si) in large volumes and with good charge carrier transport properties has been produced and achieved success as a radiation detector material over the past few years due to its relatively low cost as well as the availability of well-established processing technologies. One application of that technology is in the fabrication of various position-sensing topologies from which the incident radiation's direction can be determined. We have succeeded in developing the modeling tools for investigating different position-sensing schemes and used those tools to examine both amplitude-based and time-based methods, an assessment that indicates that fine position-sensing can be achieved with simpler readout designs than are conventionally deployed. This realization can make ubiquitous and inexpensive deployment of special nuclear materials (SNM) detecting technology becomes more feasible because if one can deploy position-sensitive semiconductor detectors with only one or two contacts per side. For this purpose, we have described the delay-line radiation detector and its optimized fabrication. The semiconductor physics were simulated, the results from which guided the fabrication of the guard ring structure and the detector electrode, both of which included metal-field-plates. The measured improvement in the leakage current was confirmed with the fabricated devices, and the structures successfully suppressed soft-breakdown. We also demonstrated that fabricating an asymmetric strip-line structure successfully minimizing the pulse shaping and increases the distance through which one can propagate the information of the deposited charge distribution. With fabricated delay-line detectors we can acquire alpha spectra (Am-241) and gamma spectra (Ba-133, Co-57 and Cd-109). The delay-line detectors can therefore be used to extract the charge information from both ion and gamma-ray interactions. Furthermore, standard charge-sensitive circuits yield high SNR pulses. The detectors and existing electronics can therefore be used to yield imaging instruments for neutron and gamma-rays, in the case of silicon. For CZT, we would prefer to utilize current sensing to be able to clearly isolate the effects of the various charge-transport non-idealities, the full realization of which awaits the fabrication of the custom-designed TIA chip.
Contingent attentional capture or delayed allocation of attention?
NASA Technical Reports Server (NTRS)
Remington, R. W.; Folk, C. L.; McLean, J. P.
2001-01-01
Under certain circumstances, external stimuli will elicit an involuntary shift of spatial attention, referred to as attentional capture. According to the contingent involuntary orienting account (Folk, Remington, & Johnston, 1992), capture is conditioned by top-down factors that set attention to respond involuntarily to stimulus properties relevant to one's behavioral goals. Evidence for this comes from spatial cuing studies showing that a spatial cuing effect is observed only when cues have goal-relevant properties. Here, we examine alternative, decision-level explanations of the spatial cuing effect that attribute evidence of capture to postpresentation delays in the voluntary allocation of attention, rather than to on-line involuntary shifts in direct response to the cue. In three spatial cuing experiments, delayed-allocation accounts were tested by examining whether items at the cued location were preferentially processed. The experiments provide evidence that costs and benefits in spatial cuing experiments do reflect the on-line capture of attention. The implications of these results for models of attentional control are discussed.
Lai, Kueifu; Ma, Tsuhsuang; Bo, Xiao; Anlage, Steven; Shvets, Gennady
2016-01-01
Electromagnetic (EM) waves propagating through an inhomogeneous medium are generally scattered whenever the medium’s electromagnetic properties change on the scale of a single wavelength. This fundamental phenomenon constrains how optical structures are designed and interfaced with each other. Recent theoretical work indicates that electromagnetic structures collectively known as photonic topological insulators (PTIs) can be employed to overcome this fundamental limitation, thereby paving the way for ultra-compact photonic structures that no longer have to be wavelength-scale smooth. Here we present the first experimental demonstration of a photonic delay line based on topologically protected surface electromagnetic waves (TPSWs) between two PTIs which are the EM counterparts of the quantum spin-Hall topological insulators in condensed matter. Unlike conventional guided EM waves that do not benefit from topological protection, TPSWs are shown to experience multi-wavelength reflection-free time delays when detoured around sharply-curved paths, thus offering a unique paradigm for compact and efficient wave buffers and other devices. PMID:27345575
DOE Office of Scientific and Technical Information (OSTI.GOV)
Schuuring, Janneke; Department of Neurology, Groene Hart Hospital, Gouda; Bussink, Johan
Purpose: The combination of irradiation and the antiangiogenic compound SU5416 was tested and compared with irradiation alone in a human glioblastoma tumor line xenografted in nude mice. The aim of this study was to monitor microenvironmental changes and growth delay. Methods and materials: A human glioblastoma xenograft tumor line was implanted in nude mice. Irradiations consisted of 10 Gy or 20 Gy with and without SU5416. Several microenvironmental parameters (tumor cell hypoxia, tumor blood perfusion, vascular volume, and microvascular density) were analyzed after imunohistochemical staining. Tumor growth delay was monitored for up to 200 days after treatment. Results: SU5416, whenmore » combined with irradiation, has an additive effect over treatment with irradiation alone. Analysis of the tumor microenvironment showed a decreased vascular density during treatment with SU5416. In tumors regrowing after reaching only a partial remission, vascular characteristics normalized shortly after cessation of SU5416. However, in tumors regrowing after reaching a complete remission, permanent microenvironmental changes and an increase of tumor necrosis with a subsequent slower tumor regrowth was found. Conclusions: Permanent vascular changes were seen after combined treatment resulting in complete remission. Antiangiogenic treatment with SU5416 when combined with irradiation has an additive effect over treatment with irradiation or antiangiogenic treatment alone.« less
DOE Office of Scientific and Technical Information (OSTI.GOV)
Heravi, Mitra; Department of Radiation Oncology, McGill University, Montreal; Segal Cancer Center, Jewish General Hospital, Montreal
2015-06-01
Purpose: ZRBA1 is a combi-molecule designed to induce DNA alkylating lesions and to block epidermal growth factor receptor (EGFR) TK domain. Inasmuch as ZRBA1 downregulates the EGFR TK-mediated antisurvival signaling and induces DNA damage, we postulated that it might be a radiosensitizer. The aim of this study was to further investigate the potentiating effect of ZRBA1 in combination with radiation and to elucidate the possible mechanisms of interaction between these 2 treatment modalities. Methods and Materials: The triple negative human breast MDA-MB-468 cancer cell line and mouse mammary cancer 4T1 cell line were used in this study. Clonogenic assay, Westernmore » blot analysis, and DNA damage analysis were performed at multiple time points after treatment. To confirm our in vitro findings, in vivo tumor growth delay assay was performed. Results: Our results show that a combination of ZRBA1 and radiation increases the radiation sensitivity of both cell lines significantly with a dose enhancement factor of 1.56, induces significant numbers of DNA strand breaks, prolongs higher DNA damage up to 24 hours after treatment, and significantly increases tumor growth delay in a syngeneic mouse model. Conclusions: Our data suggest that the higher efficacy of this combination could be partially due to increased DNA damage and delayed DNA repair process and to the inhibition of EGFR. The encouraging results of this combination demonstrated a significant improvement in treatment efficiency and therefore could be applicable in early clinical trial settings.« less
Opto-electronic oscillator: moving toward solutions based on polymer materials
NASA Astrophysics Data System (ADS)
Nguyên, Lâm Duy; Journet, Bernard; Zyss, Joseph
2008-02-01
Optoelectronic oscillators have been studied since many years now, their high spectral purity being one of their most interesting quality for photonics signal processing, communication or radio over fiber systems. One part of the structure is a long fiber optic feedback loop acting as a delay line. Different techniques have been introduced such as multiple loops in order to get very narrow spectral lines and large mode spacing. One of the problems due to long fiber loops is the size and the requirement of temperature control. In order to go toward integrated solutions it is also possible to introduce optical resonators instead of a delay line structure (as for classical electronic oscillators). But such resonators should present very high quality factor. In this paper we demonstrate solutions using resonators based on polymer materials such as PMMA-DCM. Structures such as micro-rings, micro-disks or stadium-shaped resonator have been realized at the laboratory. Quality factor of 6000 have already been achieved leading to an equivalent fiber loop of 19 m for an oscillator at 10 GHz. But it has been already theoretically proved that quality factor greater than one thousand hundred could be obtained. These resonators can be directly implemented with Mach-Zehnder optical modulators based on electro-optic polymer such as PMMA-DR1 leading to integrated solutions. And in the future it should be also possible to add a laser made with polymer material, with a structure as stadium-shape polymer micro-laser. The fully integrated photonic chip is not so far. The last important function to be implemented is the tuning of the oscillation frequency.
Hot spine loops and the nature of a late-phase solar flare
DOE Office of Scientific and Technical Information (OSTI.GOV)
Sun, Xudong; Todd Hoeksema, J.; Liu, Yang
2013-12-01
The fan-spine magnetic topology is believed to be responsible for many curious features in solar explosive events. A spine field line links distinct flux domains, but direct observation of such a feature has been rare. Here we report a unique event observed by the Solar Dynamic Observatory where a set of hot coronal loops (over 10 MK) connected to a quasi-circular chromospheric ribbon at one end and a remote brightening at the other. Magnetic field extrapolation suggests that these loops are partly tracers of the evolving spine field line. Continuous slipping- and null-point-type reconnections were likely at work, energizing themore » loop plasma and transferring magnetic flux within and across the fan quasi-separatrix layer. We argue that the initial reconnection is of the 'breakout' type, which then transitioned to a more violent flare reconnection with an eruption from the fan dome. Significant magnetic field changes are expected and indeed ensued. This event also features an extreme-ultraviolet (EUV) late phase, i.e., a delayed secondary emission peak in warm EUV lines (about 2-7 MK). We show that this peak comes from the cooling of large post-reconnection loops beside and above the compact fan, a direct product of eruption in such topological settings. The long cooling time of the large arcades contributes to the long delay; additional heating may also be required. Our result demonstrates the critical nature of cross-scale magnetic coupling—topological change in a sub-system may lead to explosions on a much larger scale.« less
NASA Astrophysics Data System (ADS)
Wang, Yonggang; Liu, Chong
2015-10-01
Because large nonlinearity errors exist in the current tapped-delay line (TDL) style field programmable gate array (FPGA)-based time-to-digital converters (TDC), bin-by-bin calibration techniques have to be resorted for gaining a high measurement resolution. If the TDL in selected FPGAs is significantly affected by changes in ambient temperature, the bin-by-bin calibration table has to be updated as frequently as possible. The on-line calibration and calibration table updating increase the TDC design complexity and limit the system performance to some extent. This paper proposes a method to minimize the nonlinearity errors of TDC bins, so that the bin-by-bin calibration may not be needed while maintaining a reasonably high time resolution. The method is a two pass approach: By a bin realignment, the large number of wasted zero-width bins in the original TDL is reused and the granularity of the bins is improved; by a bin decimation, the bin size and its uniformity is traded-off, and the time interpolation by the delay line turns more precise so that the bin-by-bin calibration is not necessary. Using Xilinx 28 nm FPGAs, in which the TDL property is not very sensitive to ambient temperature, the proposed TDC achieves approximately 15 ps root-mean-square (RMS) time resolution by dual-channel measurements of time-intervals over the range of operating temperature. Because of removing the calibration and less logic resources required for the data post-processing, the method has bigger multi-channel capability.
A Never-Get-Lost Reading Program
ERIC Educational Resources Information Center
Moore, William
2010-01-01
This paper proposes a reading support technique for Arabic students of English. These students must overcome the L1 interference "reversal of reading direction." PowerPoint presentations, utilizing a simple fade effect with adjustable delay between words such that the text appears nicely in a left-to-right manner, line by line with voice…
NASA Technical Reports Server (NTRS)
Peterson, B. M.; Berlind, P.; Bertram, R.; Bischoff, K.; Bochkarev, N. G.; Burenkov, A. N.; Calkins, M.; Carrasco, L.; Chavushyan, V. H.
2002-01-01
We present the final installment of an intensive 13 year study of variations of the optical continuum and broad H beta emission line in the Seyfert 1 galaxy NGC 5548. The database consists of 1530 optical continuum measurements and 1248 H beta measurements. The H beta variations follow the continuum variations closely, with a typical time delay of about 20 days. However, a year-by-year analysis shows that the magnitude of emission-line time delay is correlated with the mean continuum flux. We argue that the data are consistent with the simple model prediction between the size of the broad-line region and the ionizing luminosity, r is proportional to L(sup 1/2)(sub ion). Moreover, the apparently linear nature of the correlation between the H beta response time and the nonstellar optical continuum F(sub opt) arises as a consequence of the changing shape of the continuum as it varies, specifically F(sub opt) is proportional to F(sup 0.56)(sub UV).
Takamuku, Shinya; Gomi, Hiroaki
2015-07-22
How our central nervous system (CNS) learns and exploits relationships between force and motion is a fundamental issue in computational neuroscience. While several lines of evidence have suggested that the CNS predicts motion states and signals from motor commands for control and perception (forward dynamics), it remains controversial whether it also performs the 'inverse' computation, i.e. the estimation of force from motion (inverse dynamics). Here, we show that the resistive sensation we experience while moving a delayed cursor, perceived purely from the change in visual motion, provides evidence of the inverse computation. To clearly specify the computational process underlying the sensation, we systematically varied the visual feedback and examined its effect on the strength of the sensation. In contrast to the prevailing theory that sensory prediction errors modulate our perception, the sensation did not correlate with errors in cursor motion due to the delay. Instead, it correlated with the amount of exposure to the forward acceleration of the cursor. This indicates that the delayed cursor is interpreted as a mechanical load, and the sensation represents its visually implied reaction force. Namely, the CNS automatically computes inverse dynamics, using visually detected motions, to monitor the dynamic forces involved in our actions. © 2015 The Author(s) Published by the Royal Society. All rights reserved.
Cai, Mingbo; Stetson, Chess; Eagleman, David M.
2012-01-01
When observers experience a constant delay between their motor actions and sensory feedback, their perception of the temporal order between actions and sensations adapt (Stetson et al., 2006). We present here a novel neural model that can explain temporal order judgments (TOJs) and their recalibration. Our model employs three ubiquitous features of neural systems: (1) information pooling, (2) opponent processing, and (3) synaptic scaling. Specifically, the model proposes that different populations of neurons encode different delays between motor-sensory events, the outputs of these populations feed into rivaling neural populations (encoding “before” and “after”), and the activity difference between these populations determines the perceptual judgment. As a consequence of synaptic scaling of input weights, motor acts which are consistently followed by delayed sensory feedback will cause the network to recalibrate its point of subjective simultaneity. The structure of our model raises the possibility that recalibration of TOJs is a temporal analog to the motion aftereffect (MAE). In other words, identical neural mechanisms may be used to make perceptual determinations about both space and time. Our model captures behavioral recalibration results for different numbers of adapting trials and different adapting delays. In line with predictions of the model, we additionally demonstrate that temporal recalibration can last through time, in analogy to storage of the MAE. PMID:23130010
Maiga, Almoustapha Issiaka; Fofana, Djeneba Bocar; Cisse, Mamadou; Diallo, Fodié; Maiga, Moussa Youssoufa; Traore, Hamar Alassane; Maiga, Issouf Alassane; Sylla, Aliou; Fofana, Dionke; Taiwo, Babafemi; Murphy, Robert; Katlama, Christine; Tounkara, Anatole; Calvez, Vincent; Marcelin, Anne-Geneviève
2012-01-01
Objectives We describe the outcomes of second-line drug resistance profiles and predict the efficacy of drugs for third-line therapy in patients monitored without the benefit of plasma HIV-1 RNA viral load (VL) or resistance testing. Methods We recruited 106 HIV-1-infected patients after second-line treatment failure in Mali. VL was determined by the Abbott RealTime system and the resistance by the ViroSeq HIV-1 genotyping system. The resistance testing was interpreted using the latest version of the Stanford algorithm. Results Among the 106 patients, 93 had isolates successfully sequenced. The median age, VL and CD4 cells were respectively 35 years, 72 000 copies/mL and 146 cells/mm3. Patients were exposed to a median of 4 years of treatment and to six antiretrovirals. We found 20% of wild-type viruses. Resistance to etravirine was noted in 38%, to lopinavir in 25% and to darunavir in 12%. The duration of prior nucleos(t)ide reverse transcriptase inhibitor exposure was associated with resistance to abacavir (P < 0.0001) and tenofovir (P = 0.0001), and duration of prior protease inhibitor treatment with resistance to lopinavir (P < 0.0001) and darunavir (P = 0.06). Conclusion Long duration of therapy prior to failure was associated with high levels of resistance and is directly related to limited access to VL monitoring and delayed switches to second-line treatment, precluding efficacy of drugs for third-line therapy. This study underlines the need for governments and public health organizations to recommend the use of VL monitoring and also the availability of darunavir and raltegravir for third-line therapies in the context of limited-resource settings. PMID:22888273
Alterations of mitochondrial DNA in CEM cells selected for resistance toward ddC toxicity.
Bjerke, M; Franco, M; Johansson, M; Balzarini, J; Karlsson, A
2006-01-01
2 ',3 '-dideoxycytidine (ddC) is a nucleoside analog that has been shown to produce a delayed toxicity which may be due to the depletion of mitochondrial DNA (mtDNA). In order to gain further understanding of the events involved in mitochondrial toxicity, two different CEM cell lines were selected for resistance to the delayed ddC toxicity.
A loose bolt delays loading of Endeavour's external tank
NASA Technical Reports Server (NTRS)
2000-01-01
This loose bracket, observed hanging down from the side of the White Room at Launch Pad 39B, delayed loading of Endeavour's external tank by several hours to allow technicians to remove it. A 'U' bolt connects the bracket to a fire suppression water line attached to the exterior of the White Room. The loose bolt could have possibly created a debris hazard.
Using Crowdsourcing to Examine Relations Between Delay and Probability Discounting
Jarmolowicz, David P.; Bickel, Warren K.; Carter, Anne E.; Franck, Christopher T.; Mueller, E. Terry
2016-01-01
Although the extensive lines of research on delay and/or probability discounting have greatly expanded our understanding of human decision-making processes, the relation between these two phenomena remains unclear. For example, some studies have reported robust associations between delay and probability discounting, whereas others have failed to demonstrate a consistent relation between the two. The current study sought to clarify this relation by examining the relation between delay and probability discounting in a large sample of internet users (n= 904) using the Amazon Mechanical Turk (AMT) crowdsourcing service. Because AMT is a novel data collection platform, the findings were validated through the replication of a number of previously established relations (e.g., relations between delay discounting and cigarette smoking status). A small but highly significant positive correlation between delay and probability discounting rates was obtained, and principal component analysis suggested that two (rather than one) components were preferable to account for the variance in both delay and probability discounting. Taken together, these findings suggest that delay and probability discounting may be related, but are not manifestations of a single component (e.g., impulsivity). PMID:22982370
Automatic toilet seat lowering apparatus
Guerty, Harold G.
1994-09-06
A toilet seat lowering apparatus includes a housing defining an internal cavity for receiving water from the water supply line to the toilet holding tank. A descent delay assembly of the apparatus can include a stationary dam member and a rotating dam member for dividing the internal cavity into an inlet chamber and an outlet chamber and controlling the intake and evacuation of water in a delayed fashion. A descent initiator is activated when the internal cavity is filled with pressurized water and automatically begins the lowering of the toilet seat from its upright position, which lowering is also controlled by the descent delay assembly. In an alternative embodiment, the descent initiator and the descent delay assembly can be combined in a piston linked to the rotating dam member and provided with a water channel for creating a resisting pressure to the advancing piston and thereby slowing the associated descent of the toilet seat. A toilet seat lowering apparatus includes a housing defining an internal cavity for receiving water from the water supply line to the toilet holding tank. A descent delay assembly of the apparatus can include a stationary dam member and a rotating dam member for dividing the internal cavity into an inlet chamber and an outlet chamber and controlling the intake and evacuation of water in a delayed fashion. A descent initiator is activated when the internal cavity is filled with pressurized water and automatically begins the lowering of the toilet seat from its upright position, which lowering is also controlled by the descent delay assembly. In an alternative embodiment, the descent initiator and the descent delay assembly can be combined in a piston linked to the rotating dam member and provided with a water channel for creating a resisting pressure to the advancing piston and thereby slowing the associated descent of the toilet seat.
Excimer-laser-induced shock wave and its dependence on atmospheric environment
NASA Astrophysics Data System (ADS)
Krueger, Ronald R.; Krasinski, Jerzy S.; Radzewicz, Czeslaw
1993-06-01
High speed shadow photography is performed on excimer laser ablated porcine corneas and rubber stoppers to capture the excimer laser induced shock waves at various time delays between 40 and 320 nanoseconds. The shock waves in air, nitrogen, and helium are recorded by tangentially illuminating the ablated surface with a tunable dye laser, the XeCl excimer laser pulse. The excimer laser ablates the specimen and excites the dye laser, which is then passed through an optical delay line before illuminating the specimen. The shadow of the shock wave produced during ablation is then cast on a screen and photographed with a CCD video camera. The system is pulsed at 30 times per second to allow a video recording of the shock wave at a fixed time delay. We conclude that high energy acoustic waves and gaseous particles are liberated during excimer laser corneal ablation, and dissipate on a submicrosecond time scale. The velocity of their dissipation is dependent on the atmospheric environment and can be increased two-fold when the ablation is performed in a helium atmosphere. Therefore, local temperature increases due to the liberation of high energy gases may be reduced by using helium during corneal photoablation.
Radiation from lightning return strokes over a finitely conducting earth
NASA Technical Reports Server (NTRS)
Le Vine, D. M.; Gesell, L.; Kao, Michael
1986-01-01
The effects of the conductivity of the earth on radiation from lightning return strokes are examined theoretically using a piecewise linear transmission line model for the return stroke. First, calculations are made of the electric field radiated during the return stroke, and then this electric field is used to compute the response of conventional AM radio receivers and electric field change systems during the return stroke. The calculations apply to the entire transient waveform (they are not restricted to the initial portions of the return stroke) and yield fast field changes and RF radiation in agreement with measurements made during real lightning. This research was motivated by measurements indicating that a time delay exists between the time of arrival of the fast electric field change and the RF radiation from first return strokes. The time delay is on the order of 20 microsec for frequencies in the HF-UHF range for lightning in Florida. The time delay is obtained theoretically in this paper. It occurs when both the effects of attenuation due to conductivity of the earth, and the finite velocity of propagation of the current pulse up the return stroke channel, are taken into account in the model.
NASA Astrophysics Data System (ADS)
van As, D.; Mikkelsen, A. B.; Holtegaard Nielsen, M.; Claesson Liljedahl, L.; Lindback, K.; Pitcher, L. H.; Hasholt, B.
2016-12-01
A 12.000 km2 area of the Greenland ice sheet discharges meltwater via the proglacial Watson River in west Greenland. In a ten-year time span of continuous monitoring (2006-2015), the river discharged 3.8 km3 to 11.2 km3 yr-1. The large interannual variability is for an important part explained by hypsometric amplification: the flattening of the ice sheet with elevation adds 70% meltwater discharge sensitivity to atmospheric temperature. Comparing river discharge with ice sheet surface meltwater production from an observation-based surface mass balance model we quantify multiple-day routing delays for meltwater transit through the supra-, en-, sub- and proglacial system. This delay increases with ice sheet surface elevation: on average five days for surface water at the previous-known equilibrium line altitude (ELA) of ca. 1550 m, and seven days at the 2009-2015 ELA of ca. 1800 m above sea level. A flooding of the Kangerlussuaq bridge as in July 2012 thus requires a multi-day high-melt episode and can therefore be anticipated by in-situ monitoring of ice sheet melt. No evidence of significant en- or subglacial meltwater retention is found.
The Thomson scattering system at Wendelstein 7-X
NASA Astrophysics Data System (ADS)
Pasch, E.; Beurskens, M. N. A.; Bozhenkov, S. A.; Fuchert, G.; Knauer, J.; Wolf, R. C.
2016-11-01
This paper describes the design of the Thomson scattering system at the Wendelstein 7-X stellarator. For the first operation campaign we installed a 10 spatial channel system to cover a radial half profile of the plasma cross section. The start-up system is based on one Nd:YAG laser with 10 Hz repetition frequency, one observation optics, five fiber bundles with one delay line each, and five interference filter polychromators with five spectral channels and silicon avalanche diodes as detectors. High dynamic range analog to digital converters with 14 bit, 1 GS/s are used to digitize the signals. The spectral calibration of the system was done using a pulsed super continuum laser together with a monochromator. For density calibration we used Raman scattering in nitrogen gas. Peaked temperature profiles and flat density profiles are observed in helium and hydrogen discharges.
On reliable control system designs. Ph.D. Thesis; [actuators
NASA Technical Reports Server (NTRS)
Birdwell, J. D.
1978-01-01
A mathematical model for use in the design of reliable multivariable control systems is discussed with special emphasis on actuator failures and necessary actuator redundancy levels. The model consists of a linear time invariant discrete time dynamical system. Configuration changes in the system dynamics are governed by a Markov chain that includes transition probabilities from one configuration state to another. The performance index is a standard quadratic cost functional, over an infinite time interval. The actual system configuration can be deduced with a one step delay. The calculation of the optimal control law requires the solution of a set of highly coupled Riccati-like matrix difference equations. Results can be used for off-line studies relating the open loop dynamics, required performance, actuator mean time to failure, and functional or identical actuator redundancy, with and without feedback gain reconfiguration strategies.
Saifodine, Abuchahama; Gudo, Paula Samo; Sidat, Mohsin; Black, James
2013-06-07
TB control is based on the rapid identification of cases and their effective treatment. However, many studies have shown that there are important delays in diagnosis and treatment of patients with TB. The purpose of this study was to assess the prevalence of and identify risk factors associated with patient delay and health system delay among newly diagnosed patients with pulmonary TB. A cross sectional study was carried out in Beira city, Mozambique between September 2009 and February 2010. Patients in the first month of treatment were consecutively selected to this study if they had a diagnosis of pulmonary TB, had no history of previous TB treatment, and were 18 years or older and provided informed consent. Data was obtained through a questionnaire administered to the patients and from patients' files. Among the 622 patients included in the study the median age was 32 years (interquartile range, 26-40) and 272 (43.7%) were females. The median total delay, patient delay and health system delay was 150 days (interquartile range, 91-240), 61 days (28-113) and 62 days (37-120), respectively. The contribution of patient delay and health system delay to total delay was similar. Farming, visiting first a traditional healer, low TB knowledge and coexistence of a chronic disease were associated with increased patient delay. More than two visits to a health facility, farming and coexistence of a chronic disease were associated with increased health system delay. This study revealed a long total delay with a similar contribution of patient delay and health system delay. To reduce the total delay in this setting we need a combination of interventions to encourage patients to seek appropriate health care earlier and to expedite TB diagnosis within the health care system.
Differential acceleration in the final beam lines of a Heavy Ion Fusion driver
Friedman, Alex
2013-10-19
A long-standing challenge in the design of a Heavy Ion Fusion power plant is that the ion beams entering the target chamber, which number of order a hundred, all need to be routed from one or two multi-beam accelerators through a set of transport lines. The beams are divided into groups, which each have unique arrival times and may have unique kinetic energies. It is also necessary to arrange for each beam to enter the target chamber from a prescribed location on the periphery of that chamber. Furthermore, it has generally been assumed that additional constraints must be obeyed: thatmore » the path lengths of the beams in a group must be equal, and that any delay of \\main-pulse" beams relative to \\foot-pulse" beams must be provided by the insertion of large delay-arcs in the main beam transport lines. Here we introduce the notion of applying \\di erential acceleration" to individual beams or sets of beam at strategic stages of the transport lines. That is, by accelerating some beams \\sooner" and others \\later," it is possible to simplify the beam line con guration in a number of cases. For example, the time delay between the foot and main pulses can be generated without resorting to large arcs in the main-pulse beam lines. It is also possible to use di erential acceleration to e ect the simultaneous arrival on target of a set of beams ( e.g., for the foot-pulse) without requiring that their path lengths be precisely equal. We illustrate the technique for two model con gurations, one corresponding to a typical indirect-drive scenario requiring distinct foot and main energies, and the other to an ion-driven fast-ignition scenario wherein the foot and main beams share a common energy.« less
NASA Astrophysics Data System (ADS)
Lester, R.; Zhai, Y.; Corr, C.; Howard, J.
2016-02-01
This paper describes a coherence imaging system designed for spectroscopic Doppler measurements of ion light in a low-temperature (T e < 10 eV) helicon-produced argon plasma. Observation of the very small Doppler broadening of the Ar II 488 nm emission line requires very high spectral resolution, or equivalently, very large interferometric optical path delay (comparable with the coherence length of the emission line). For these polarization interferometers, this can only be achieved using large thicknesses (100 mm) of birefringent crystal. This poses special design challenges including the application of field-widening techniques and the development of passive thermal stabilization of the optical phase offset. We discuss the measurement principles and the optical design of these systems and present measurements of the line-integrated emissivity, and ion flow and ion temperatures along with tomographic reconstructions of the local values, for a cylindrical low temperature helicon discharge in a linear magnetized device with downstream magnetic mirror. Key results reveal a hollow edge-peaked temperature profile (central temperature ∼0.1 eV) and sheared rigid-body rotational flows and axial flows which are comparable with the ion thermal speed. The emission line brightness, ion temperature and azimuthal ion flows are all found to increase with increased mirror magnetic field strength.
The FERMIatElettra FEL Photon Transport System
NASA Astrophysics Data System (ADS)
Zangrando, M.; Cudin, I.; Fava, C.; Godnig, R.; Kiskinova, M.; Masciovecchio, C.; Parmigiani, F.; Rumiz, L.; Svetina, C.; Turchet, A.; Cocco, D.
2010-06-01
The FERMI@Elettra free electron laser (FEL) user facility is under construction at Sincrotrone Trieste (Italy), and it will be operative in late 2010. It is based on a seeded scheme providing an almost perfect transform-limited and fully spatially coherent photon beam. FERMI@Elettra will cover the wavelength range 100 to 3 nm with the fundamental harmonics, and down to 1 nm with higher harmonics. We present the layout of the photon beam transport system that includes: the first common part providing on-line and shot-to-shot beam diagnostics, called PADReS (Photon Analysis Delivery and Reduction System), and 3 independent beamlines feeding the experimental stations. Particular emphasis is given to the solutions adopted to preserve the wavefront, and to avoid damage on the different optical elements. Peculiar FEL devices, not common in the Synchrotron Radiation facilities, are described in more detail, e.g. the online photon energy spectrometer measuring shot-by-shot the spectrum of the emitted radiation, the beam splitting and delay line system dedicated to cross/auto correlation and pump-probe experiments, and the wavefront preserving active optics adapting the shape and size of the focused spot to meet the needs of the different experiments.
Time-delayed chameleon: Analysis, synchronization and FPGA implementation
NASA Astrophysics Data System (ADS)
Rajagopal, Karthikeyan; Jafari, Sajad; Laarem, Guessas
2017-12-01
In this paper we report a time-delayed chameleon-like chaotic system which can belong to different families of chaotic attractors depending on the choices of parameters. Such a characteristic of self-excited and hidden chaotic flows in a simple 3D system with time delay has not been reported earlier. Dynamic analysis of the proposed time-delayed systems are analysed in time-delay space and parameter space. A novel adaptive modified functional projective lag synchronization algorithm is derived for synchronizing identical time-delayed chameleon systems with uncertain parameters. The proposed time-delayed systems and the synchronization algorithm with controllers and parameter estimates are then implemented in FPGA using hardware-software co-simulation and the results are presented.
Maps of interaural delay in the owl's nucleus laminaris
Shah, Sahil; McColgan, Thomas; Ashida, Go; Kuokkanen, Paula T.; Brill, Sandra; Kempter, Richard; Wagner, Hermann
2015-01-01
Axons from the nucleus magnocellularis form a presynaptic map of interaural time differences (ITDs) in the nucleus laminaris (NL). These inputs generate a field potential that varies systematically with recording position and can be used to measure the map of ITDs. In the barn owl, the representation of best ITD shifts with mediolateral position in NL, so as to form continuous, smoothly overlapping maps of ITD with iso-ITD contours that are not parallel to the NL border. Frontal space (0°) is, however, represented throughout and thus overrepresented with respect to the periphery. Measurements of presynaptic conduction delay, combined with a model of delay line conduction velocity, reveal that conduction delays can account for the mediolateral shifts in the map of ITD. PMID:26224776
Liu, Yang; Tong, Shoufeng; Chang, Shuai; Song, Yansong; Dong, Yan; Zhao, Xin; An, Zhe; Yu, Fuwan
2018-05-10
Optical phase-locked loops are an effective detection method in high-speed and long-distance laser communication. Although this method can detect weak signal light and maintain a small bit error rate, it is difficult to perform because identifying the phase difference between the signal light and the local oscillator accurately has always been a technical challenge. Thus, a series of studies is conducted to address this issue. First, a delayed exclusive or gate (XOR) phase detector with multi-level loop compound control is proposed. Then, a 50 ps delay line and relative signal-to-noise ratio control at 15 dB are produced through theoretical derivation and simulation. Thereafter, a phase discrimination module is designed on a 15 cm×5 cm printed circuit board board. Finally, the experiment platform is built for verification. Experimental results show that the phase discrimination range is -1.1 to 1.1 GHz, and the gain is 0.82 mV/MHz. Three times the standard deviation, that is, 0.064 V, is observed between the test and theoretical values. The accuracy of phase detection is better than 0.07 V, which meets the design standards. A coherent carrier recovery test system is established. The delayed XOR gate has good performance in this system. When the communication rate is 5 Gbps, the system realizes a bit error rate of 1.55×10 -8 when the optical power of the signal is -40.4 dBm. When the communication rate is increased to 10 Gbps, the detection sensitivity drops to -39.5 dBm and still shows good performance in high-speed communications. This work provides a reference for future high-speed coherent homodyne detection in space. Ideas for the next phase of this study are presented at the end of this paper.
Stability and delay sensitivity of neutral fractional-delay systems.
Xu, Qi; Shi, Min; Wang, Zaihua
2016-08-01
This paper generalizes the stability test method via integral estimation for integer-order neutral time-delay systems to neutral fractional-delay systems. The key step in stability test is the calculation of the number of unstable characteristic roots that is described by a definite integral over an interval from zero to a sufficient large upper limit. Algorithms for correctly estimating the upper limits of the integral are given in two concise ways, parameter dependent or independent. A special feature of the proposed method is that it judges the stability of fractional-delay systems simply by using rough integral estimation. Meanwhile, the paper shows that for some neutral fractional-delay systems, the stability is extremely sensitive to the change of time delays. Examples are given for demonstrating the proposed method as well as the delay sensitivity.
Khakbazan, Zohreh; Taghipour, Ali; Latifnejad Roudsari, Robab; Mohammadi, Eesa
2014-01-01
Background and Objective Patient delay makes a critical contribution to late diagnosis and poor survival in cases of breast cancer. Identifying the factors that influence patient delay could provide information for adopting strategies that shorten this delay. The aim of this meta-ethnography was to synthesize existing qualitative evidence in order to gain a new understanding of help seeking behavior in women with self-discovered breast cancer symptoms and to determine the factors that influence patient delay. Methods The design was a meta-ethnography approach. A systematic search of the articles was performed in different databases including Elsevier, PubMed, ProQuest and SCOPUS. Qualitative studies with a focus on help seeking behaviors in women with self-discovered breast cancer symptoms and patient delay, published in the English language between 1990 and 2013 were included. The quality appraisal of the articles was carried out using the Critical Appraisal Skills Programme qualitative research checklist and 13 articles met the inclusion criteria. The synthesis was conducted according to Noblit and Hare’s meta-ethnographic approach (1988), through reciprocal translational analysis and lines-of-argument. Findings The synthesis led to identification of eight repeated key concepts including: symptom detection, initial symptom interpretation, symptom monitoring, social interaction, emotional reaction, priority of medical help, appraisal of health services and personal-environmental factors. Symptom interpretation is identified as the important step of the help seeking process and which changed across the process through active monitoring of their symptoms, social interactions and emotional reactions. The perceived seriousness of the situation, priority to receive medical attention, perceived inaccessibility and unacceptability of the health care system influenced women’s decision-making about utilizing health services. Conclusion Help seeking processes are influenced by multiple factors. Educational programs aimed at correcting misunderstandings, erroneous social beliefs and improving self-awareness could provide key strategies to improve health policy which would reduce patient delay. PMID:25470732
Control-based method to identify underlying delays of a nonlinear dynamical system.
Yu, Dongchuan; Frasca, Mattia; Liu, Fang
2008-10-01
We suggest several stationary state control-based delay identification methods which do not require any structural information about the controlled systems and are applicable to systems described by delayed ordinary differential equations. This proposed technique includes three steps: (i) driving a system to a steady state; (ii) perturbing the control signal for shifting the steady state; and (iii) identifying all delays by detecting the time that the system is abruptly drawn out of stationarity. Some aspects especially important for applications are discussed as well, including interaction delay identification, stationary state convergence speed, performance comparison, and the influence of noise on delay identification. Several examples are presented to illustrate the reliability and robustness of all delay identification methods suggested.
Stability of uncertain impulsive complex-variable chaotic systems with time-varying delays.
Zheng, Song
2015-09-01
In this paper, the robust exponential stabilization of uncertain impulsive complex-variable chaotic delayed systems is considered with parameters perturbation and delayed impulses. It is assumed that the considered complex-variable chaotic systems have bounded parametric uncertainties together with the state variables on the impulses related to the time-varying delays. Based on the theories of adaptive control and impulsive control, some less conservative and easily verified stability criteria are established for a class of complex-variable chaotic delayed systems with delayed impulses. Some numerical simulations are given to validate the effectiveness of the proposed criteria of impulsive stabilization for uncertain complex-variable chaotic delayed systems. Copyright © 2015 ISA. Published by Elsevier Ltd. All rights reserved.
NASA Astrophysics Data System (ADS)
Ishbulatov, Yu. M.; Karavaev, A. S.; Kiselev, A. R.; Semyachkina-Glushkovskaya, O. V.; Postnov, D. E.; Bezruchko, B. P.
2018-04-01
A method for the reconstruction of time-delayed feedback system is investigated, which is based on the detection of synchronous response of a slave time-delay system with respect to the driving from the master system under study. The structure of the driven system is similar to the structure of the studied time-delay system, but the feedback circuit is broken in the driven system. The method efficiency is tested using short and noisy data gained from an electronic chaotic oscillator with time-delayed feedback.
The effect of delay line on the performance of a fiber optic interferometric sensor
NASA Astrophysics Data System (ADS)
Lin, Yung-Li; Lin, Ken-Huang; Lin, Wuu-Wen; Chen, Mao-Hsiung
2007-09-01
The optical fiber has the features of low loss and wide bandwidth; it has replaced the coaxial cable as the mainstream of the communication system in recent years. Because of its high sensitivity characteristic, the interferometer is usually applied to long distance, weak signal detection. In general, if the area to be monitored is located far away, the weak signal will make it uneasy to detect. An interferometer is used for phase detection. Thus, the hydrophone which is based on interferometric fiber optic sensor has extremely high sensitivity. Sagnac interferometric hydrophone has low noise of marine environment, which is more suitably used to detect underwater acoustic signal than that of a Mach-Zehnder interferometer. In this paper, we propose the configuration of dual Sagnac interferometer, and use the mathematical methods to drive and design optimal two delay fiber lengths, which can enlarge the dynamic range of underwater acoustic detection. In addition, we also use software simulation to design optimal two delay fiber lengths. The experimental configuration of dual Sagnac interferometer with two optical delay line is shown as Fig. 1. The maximum and minimum measurable phase signal value of dual Sagnac interferometer (L II=2 km, L 4=222.2 m), shown in Fig. 3. The fiber optic sensor head is of mandrel type. The acoustic window is made of silicon rubbers. It was shown that we can increase their sensitivities by increasing number of wrapping fiber coils. In our experiment, the result shows that among all the mandrel sensor heads, the highest dynamic range is up to 37.6 +/- 1.4 dB, and its sensitivity is -223.3 +/-1.7 dB re V / 1μ Pa. As for the configuration of the optical interferometers, the intensity of the dual Sagnac interferometer is 20 dB larger than its Sagnac counterpart. Its dynamic range is above 66 dB where the frequency ranges is between 50 ~ 400 Hz, which is 24 dB larger than that of the Sagnac interferometer with the sensitivity of -192.0 dB re V / l μPa. In addition, by using software simulation to design optimal lengths of delay fibers, we can increase the dynamic range of interferometer on underwater acoustic detection. This paper verifies that, by means of adjusting the length of these two delay fibers, we can actually increase the dynamic range of acoustic signal detection.
A loose bolt delays loading of Endeavour's external tank
NASA Technical Reports Server (NTRS)
2000-01-01
A closeup reveals the loose bracket, observed hanging down from the side of the White Room at Launch Pad 39B, that delayed loading of Endeavour's external tank by several hours to allow technicians to remove it. A 'U' bolt connects the bracket to a fire suppression water line attached to the exterior of the White Room. The loose bolt could have possibly created a debris hazard.
1984-08-15
for the Same Signal 30 3 -1 Schematic Diagrams of Two Configurations with SOI/ CMOS and Bipolar Devices Fabricated on the Same Si Wafer. The Bipolar...Waveform of 39-Stage SOI/ CMOS Ring Oscillator for 5-V Supply Voltage. The Propagation Delay per Stage is 藨 ps 33 3 -4 Common-Emitter I-V...multiple beam splitters and delay lines. 3 . MATERIALS RESEARCH Two merged CMOS ! bipolar technologies utilizing S01 films have been developed for
Very long baseline interferometry using a communication satellite
NASA Technical Reports Server (NTRS)
Swenson, G. W., Jr.
1975-01-01
A planned experiment is discussed in long-baseline interferometry, using the Communications Technology Satellite to transmit the base-band signal from one telescope to another for real-time correlation. A 20 megabit data rate is planned, calling for a delay-line of 10 MHz bandwidth and controllable delay up to 275 milliseconds. A number of sources will be studied on baselines from Ontario to West Virginia and California.
NASA Astrophysics Data System (ADS)
Xue, Xiaoxiao; Xuan, Yi; Bao, Chengying; Li, Shangyuan; Zheng, Xiaoping; Zhou, Bingkun; Qi, Minghao; Weiner, Andrew M.
2018-06-01
Microwave phased array antennas (PAAs) are very attractive to defense applications and high-speed wireless communications for their abilities of fast beam scanning and complex beam pattern control. However, traditional PAAs based on phase shifters suffer from the beam-squint problem and have limited bandwidths. True-time-delay (TTD) beamforming based on low-loss photonic delay lines can solve this problem. But it is still quite challenging to build large-scale photonic TTD beamformers due to their high hardware complexity. In this paper, we demonstrate a photonic TTD beamforming network based on a miniature microresonator frequency comb (microcomb) source and dispersive time delay. A method incorporating optical phase modulation and programmable spectral shaping is proposed for positive and negative apodization weighting to achieve arbitrary microwave beam pattern control. The experimentally demonstrated TTD beamforming network can support a PAA with 21 elements. The microwave frequency range is $\\mathbf{8\\sim20\\ {GHz}}$, and the beam scanning range is $\\mathbf{\\pm 60.2^\\circ}$. Detailed measurements of the microwave amplitudes and phases are performed. The beamforming performances of Gaussian, rectangular beams and beam notch steering are evaluated through simulations by assuming a uniform radiating antenna array. The scheme can potentially support larger PAAs with hundreds of elements by increasing the number of comb lines with broadband microcomb generation.
A dual V t disturb-free subthreshold SRAM with write-assist and read isolation
NASA Astrophysics Data System (ADS)
Bhatnagar, Vipul; Kumar, Pradeep; Pandey, Neeta; Pandey, Sujata
2018-02-01
This paper presents a new dual V t 8T SRAM cell having single bit-line read and write, in addition to Write Assist and Read Isolation (WARI). Also a faster write back scheme is proposed for the half selected cells. A high V t device is used for interrupting the supply to one of the inverters for weakening the feedback loop for assisted write. The proposed cell provides an improved read static noise margin (RSNM) due to the bit-line isolation during the read. Static noise margins for data read (RSNM), write (WSNM), read delay, write delay, data retention voltage (DRV), leakage and average powers have been calculated. The proposed cell was found to operate properly at a supply voltage as small as 0.41 V. A new write back scheme has been suggested for half-selected cells, which uses a single NMOS access device and provides reduced delay, pulse timing hardware requirements and power consumption. The proposed new WARI 8T cell shows better performance in terms of easier write, improved read noise margin, reduced leakage power, and less delay as compared to the existing schemes that have been available so far. It was also observed that with proper adjustment of the cell ratio the supply voltage can further be reduced to 0.2 V.
Assembly line inspection using neural networks
NASA Astrophysics Data System (ADS)
McAulay, Alastair D.; Danset, Paul; Wicker, Devert W.
1990-09-01
A user friendly flexible system for assembly line part inspection which learns good and bad parts is described. The system detects missing rivets and springs in clutch drivers. The system extracts features in a circular region of interest from a video image processes these using a Fast Fourier Transform for rotation invariance and uses this as inputs to a neural network trained with back-propagation. The advantage of a learning system is that expensive reprogramming and delays are avoided when a part is modified. Two cases were considered. The first one could use back lighting in that surface effects could be ignored. The second case required front lighting because the part had a cover which prevented light from passing through the parts. 100 percent classification of good and bad parts was achieved for both back-lit and front-lit cases with a limited number of training parts available. 1. BACKGROUND A vision system to inspect clutch drivers for missing rivets and springs at the Harrison Radiator Plant of General Motors (GM) works only on parts without covers Fig. 1 and is expensive. The system does not work when there are cover plates Fig. 2 that rule out back light passing through the area of missing rivets and springs. Also the system like all such systems must be reprogrammed at significant time and cost when the system needs to classify a different fault or a
Bellaloui, Nacer; Smith, James R; Mengistu, Alemu
2017-01-01
The timing of harvest is a major factor affecting seed quality in soybean, particularly in Midsouthern USA, when rain during harvest period is not uncommon. The objective of this research was to evaluate the effects of time of harvest on soybean seed quality (seed composition, germination, seed coat boron, and lignin) in high germinability (HG) breeding lines (50% exotic) developed under high heat. The hypothesis was that seeds of HG lines possess physiological and genetic traits for a better seed quality at harvest maturity and delayed harvest. A 2-year field experiment was conducted under irrigated conditions. Results showed that, at harvest maturity, the exotic HG lines had higher seed protein, oleic acid, sugars, seed coat boron, and seed coat lignin, but lower seed oil compared with the non-exotic checks (Control), confirming our hypothesis. At 28 days after harvest maturity (delayed harvest), the content of seed protein, oleic acid, sugars, seed coat boron, and seed coat lignin were higher in some of the HG lines compared with the checks, indicating a possible involvement of these seed constituents, especially seed coat boron and seed coat lignin, in maintaining seed coat integrity and protecting seed coat against physical damage. Highly significant positive correlations were found between germination and seed protein, oleic acid, sugars, and seed coat boron and seed coat lignin. Highly significant negative correlation was found between germination and oil, linoleic acid, seed coat wrinkling, shattering, and hard seed. Yields of some HG lines were competitive with checks. This research demonstrated that time of harvesting is an important factor influencing seed protein and oil production. Also, since high oleic acid is desirable for oxidative stability, shelf-life and biodiesel properties, using HG lines could positively influence these important traits. This result should suggest to breeders of some of the advantages of selecting for high seed coat boron and lignin, and inform growers of the importance of timely harvest for maintaining high seed quality.
[Determinants of tuberculosis diagnosis delay in limited resources countries].
Ndeikoundam Ngangro, N; Chauvin, P; Halley des Fontaines, V
2012-02-01
Delayed diagnoses of pulmonary tuberculosis contribute to the spread of the epidemic. This study aims to identify risk factors associated with patient delay (from symptoms onset to the first visit), health system delay (from the first visit to the tuberculosis treatment initiation) and total delay (sum of the patient and the health system delay) in low income and high tuberculosis burden countries. A systematic literature review has been performed using the keywords: "tuberculosis"; "delay", care seeking"; "health care seeking behavior"; "diagnosis" and "treatment". Only quantitative studies showing delays for pulmonary tuberculosis adult cases were included in this review. Low income, gender, rural life, unemployment, ageing and misunderstanding the microbial cause of tuberculosis are associated with delayed diagnoses. Systemic factors including low health care coverage, patient expenditures and entry into the health system by consulting a traditional healer or a non-skilled professional delay the beginning of tuberculosis treatment. Delays can be used as indicators to evaluate tuberculosis control programs. Active case finding in the households of contagious patients can help to diminish diagnostic delays in low-income countries with high endemicity. Copyright © 2011 Elsevier Masson SAS. All rights reserved.
NASA Astrophysics Data System (ADS)
Buchari; Tarigan, U.; Ambarita, M. B.
2018-02-01
PT. XYZ is a wood processing company which produce semi-finished wood with production system is make to order. In the production process, it can be seen that the production line is not balanced. The imbalance of the production line is caused by the difference in cycle time between work stations. In addition, there are other issues, namely the existence of material flow pattern is irregular so it resulted in the backtracking and displacement distance away. This study aimed to obtain the allocation of work elements to specific work stations and propose an improvement of the production layout based on the result of improvements in the line balancing. The method used in the balancing is Ranked Positional Weight (RPW) or also known as Helgeson Birnie method. While the methods used in the improvement of the layout is the method of Systematic Layout Planning (SLP). By using Ranked Positional Weight (RPW) obtained increase in line efficiency becomes 84,86% and decreased balance delay becomes 15,14%. Repairing the layout using the method of Systematic Layout Planning (SLP) also give good results with a reduction in path length becomes 133,82 meters from 213,09 meters previously or a decrease of 37.2%.
Costs of counterdefenses to host resistance in a parasitoid of Drosophila.
Kraaijeveld, A R; Hutcheson, K A; Limentani, E C; Godfray, H C
2001-09-01
The ability of a parasitoid to evolve enhanced counterdefenses against host resistance and its possible costs were studied in a Drosophila-parasitoid system. We reared Asobara tabida (Braconidae, Hymenoptera) exclusively on D. melanogaster to impose artificial selection for improved counterdefenses against cellular encapsulation, the main host defense against parasitism. Controls were reared on D. subobscura, the main host of the population of wasps from which the laboratory culture was derived and a species that never encapsulates parasitoids. We observed improved survival and avoidance of encapsulation in all five selection lines compared to their paired control lines, although there was unexpected variation among pairs. Improved survival was associated with parasitoid eggs becoming embedded in host tissue, where they were protected from circulating haemocytes. There were no differences among lines in average adult size, fat content, egg load, or performance on D. subobscura. However, the duration of the egg stage in selection lines was longer than that of control lines, probably because of reduced nutrient and/or oxygen supply when eggs are embedded in host tissue. We suggest that this delay in hatching reduces the probability of parasitoid survival if another parasitoid egg is laid in the same host (superparasitism or multiparasitism) and hence is a cost of enhanced counterdefenses against host resistance.
Tuberculosis diagnostic delay and therapy outcomes of non-national migrants in Tel Aviv, 1998-2008.
Mor, Z; Kolb, H; Lidji, M; Migliori, Gb; Leventhal, A
2013-03-21
Non-national migrants have limited access to medical therapy. This study compares diagnostic delay and treatment outcomes of non-insured non-national migrants (NINNM) with insured Israeli citizens (IC) in the Tel Aviv tuberculosis (TB) clinic between 1998 and 2008. Patient delay was the time from symptoms onset to doctor's visit, while system delay was measured from doctor visit to anti-TB therapy administration. We randomly sampled 222 NINNM and 265 IC. NINNM were younger than IC, had lower male to female ratio and fewer smoked. They had less drug/alcohol abuse, more cavitations on chest radiography, longer patient and shorter system delay. Mean patient and system delays of all patients were 25 ± 14 and 79 ± 42 days, respectively. In multivariate analysis, being NINNM, asymptomatic or smoking predicted longer patient delay, while being asymptomatic or having additional co-morbidity predicted longer system delay. Treatment success in sputum smear-positive pulmonary TB NINNM was 81% and 95.7% in IC (p=0.01). Treatment success was not associated with patient or system delay. In multivariate analysis, work security and treatment adherence predicted treatment success. NINNM had longer patient delay and worse therapy outcome, while IC had longer system delay. Both delays should be reduced. NINNM should be informed that TB therapy is free and unlinked with deportation.
Way-Scaling to Reduce Power of Cache with Delay Variation
NASA Astrophysics Data System (ADS)
Goudarzi, Maziar; Matsumura, Tadayuki; Ishihara, Tohru
The share of leakage in cache power consumption increases with technology scaling. Choosing a higher threshold voltage (Vth) and/or gate-oxide thickness (Tox) for cache transistors improves leakage, but impacts cell delay. We show that due to uncorrelated random within-die delay variation, only some (not all) of cells actually violate the cache delay after the above change. We propose to add a spare cache way to replace delay-violating cache-lines separately in each cache-set. By SPICE and gate-level simulations in a commercial 90nm process, we show that choosing higher Vth, Tox and adding one spare way to a 4-way 16KB cache reduces leakage power by 42%, which depending on the share of leakage in total cache power, gives up to 22.59% and 41.37% reduction of total energy respectively in L1 instruction- and L2 unified-cache with a negligible delay penalty, but without sacrificing cache capacity or timing-yield.
Effect of time delay on flying qualities: An update
NASA Technical Reports Server (NTRS)
Smith, R. E.; Sarrafian, S. K.
1986-01-01
Flying qualities problems of modern, full-authority electronic flight control systems are most often related to the introduction of additional time delay in aircraft response to a pilot input. These delays can have a significant effect on the flying qualities of the aircraft. Time delay effects are reexamined in light of recent flight test experience with aircraft incorporating new technology. Data from the X-29A forward-swept-wing demonstrator, a related preliminary in-flight experiment, and other flight observations are presented. These data suggest that the present MIL-F-8785C allowable-control system time delay specifications are inadequate or, at least, incomplete. Allowable time delay appears to be a function of the shape of the aircraft response following the initial delay. The cockpit feel system is discussed as a dynamic element in the flight control system. Data presented indicate that the time delay associated with a significant low-frequency feel system does not result in the predicted degradation in aircraft flying qualities. The impact of the feel system is discussed from two viewpoints: as a filter in the control system which can alter the initial response shape and, therefore, the allowable time delay, and as a unique dynamic element whose delay contribution can potentially be discounted by special pilot loop closures.
NASA Astrophysics Data System (ADS)
Efimov, Denis; Schiffer, Johannes; Ortega, Romeo
2016-05-01
Motivated by the problem of phase-locking in droop-controlled inverter-based microgrids with delays, the recently developed theory of input-to-state stability (ISS) for multistable systems is extended to the case of multistable systems with delayed dynamics. Sufficient conditions for ISS of delayed systems are presented using Lyapunov-Razumikhin functions. It is shown that ISS multistable systems are robust with respect to delays in a feedback. The derived theory is applied to two examples. First, the ISS property is established for the model of a nonlinear pendulum and delay-dependent robustness conditions are derived. Second, it is shown that, under certain assumptions, the problem of phase-locking analysis in droop-controlled inverter-based microgrids with delays can be reduced to the stability investigation of the nonlinear pendulum. For this case, corresponding delay-dependent conditions for asymptotic phase-locking are given.
NASA Astrophysics Data System (ADS)
Pfeiffer, Adrian N.; Bell, M. Justine; Beck, Annelise R.; Mashiko, Hiroki; Neumark, Daniel M.; Leone, Stephen R.
2013-11-01
Recording the transmitted spectrum of a weak attosecond pulse through a medium, while a strong femtosecond pulse copropagates at variable delay, probes the strong-field dynamics of atoms, molecules, and solids. Usually, the interpretation of these measurements is based on the assumption of a thin medium. Here, the propagation through a macroscopic medium of helium atoms in the region of fully allowed resonances is investigated both theoretically and experimentally. The propagation has dramatic effects on the transient spectrum even at relatively low pressures (50 mbar) and short propagation lengths (1 mm). The absorption does not evolve monotonically with the product of propagation distance and pressure, but regions with characteristics of Lorentz line shapes and characteristics of Fano line shapes alternate. Criteria are deduced to estimate whether macroscopic effects can be neglected or not in a transient absorption experiment. Furthermore, the theory in the limit of single-atom response yields a general equation for Lorentz- and Fano-type line shapes at variable pulse delay.
Parker, Grace A; Sumners, Lindsay H; Zhao, Xiaoling; Honaker, Christa F; Siegel, Paul B; Cline, Mark A; Gilbert, Elizabeth R
2015-11-01
Chickens selected for low (LWS) and high (HWS) juvenile body weight (BW) for 55 generations differ in BW by 10-fold at selection age. High (HWR) and low (LWR) body weight-relaxed lines have been random-bred since the 46th generation. Our objective was to evaluate the developmental and nutritional regulation of pancreatic mRNA abundance of pancreatic and duodenal homeobox 1 (PDX1), preproinsulin (PPI), preproglucagon (PPG), and glucose transporter 2 (GLUT2). At day of hatch (DOH) and days 1, 3, 7, and 15 (D1, 3, 7 and 15, respectively), pancreas was collected and real time PCR was performed in Experiment 1. In Experiment 2, HWS and LWS were fed or delayed access to food for 72 h post-hatch, and pancreas collected at D15. There was an interaction of line and age for GLUT2 (P=0.001), PPI (P<0.0001), PPG (P=0.034), and PDX1 (P<0.0001). Expression was greater in chicks from LWR and LWS than HWR and HWS. There was an interaction of line and nutrition on PPG (P<0.0001) and GLUT2 (P=0.001) mRNA, where expression was similar among chicks that were fed but greater in LWS than HWS when chicks were delayed access to food. Thus, the first two weeks is important for maturation of pancreatic endocrine function. Long-term selection for BW is associated with differences in pancreas development, and delaying access to food at hatch may have persisting effects on glucose regulatory function. Copyright © 2015 Elsevier Inc. All rights reserved.
NASA Astrophysics Data System (ADS)
Grier, C. J.; Trump, J. R.; Shen, Yue; Horne, Keith; Kinemuchi, Karen; McGreer, Ian D.; Starkey, D. A.; Brandt, W. N.; Hall, P. B.; Kochanek, C. S.; Chen, Yuguang; Denney, K. D.; Greene, Jenny E.; Ho, L. C.; Homayouni, Y.; I-Hsiu Li, Jennifer; Pei, Liuyi; Peterson, B. M.; Petitjean, P.; Schneider, D. P.; Sun, Mouyuan; AlSayyad, Yusura; Bizyaev, Dmitry; Brinkmann, Jonathan; Brownstein, Joel R.; Bundy, Kevin; Dawson, K. S.; Eftekharzadeh, Sarah; Fernandez-Trincado, J. G.; Gao, Yang; Hutchinson, Timothy A.; Jia, Siyao; Jiang, Linhua; Oravetz, Daniel; Pan, Kaike; Paris, Isabelle; Ponder, Kara A.; Peters, Christina; Rogerson, Jesse; Simmons, Audrey; Smith, Robyn; Wang, Ran
2017-12-01
We present reverberation mapping results from the first year of combined spectroscopic and photometric observations of the Sloan Digital Sky Survey Reverberation Mapping Project. We successfully recover reverberation time delays between the g+i band emission and the broad Hβ emission line for a total of 44 quasars, and for the broad Hα emission line in 18 quasars. Time delays are computed using the JAVELIN and CREAM software and the traditional interpolated cross-correlation function (ICCF): using well-defined criteria, we report measurements of 32 Hβ and 13 Hα lags with JAVELIN, 42 Hβ and 17 Hα lags with CREAM, and 16 Hβ and eight Hα lags with the ICCF. Lag values are generally consistent among the three methods, though we typically measure smaller uncertainties with JAVELIN and CREAM than with the ICCF, given the more physically motivated light curve interpolation and more robust statistical modeling of the former two methods. The median redshift of our Hβ-detected sample of quasars is 0.53, significantly higher than that of the previous reverberation mapping sample. We find that in most objects, the time delay of the Hα emission is consistent with or slightly longer than that of Hβ. We measure black hole masses using our measured time delays and line widths for these quasars. These black hole mass measurements are mostly consistent with expectations based on the local {M}{BH}-{σ }* relationship, and are also consistent with single-epoch black hole mass measurements. This work increases the current sample size of reverberation-mapped active galaxies by about two-thirds and represents the first large sample of reverberation mapping observations beyond the local universe (z < 0.3).
Discounting of food, sex, and money.
Holt, Daniel D; Newquist, Matthew H; Smits, Rochelle R; Tiry, Andrew M
2014-06-01
Discounting is a useful framework for understanding choice involving a range of delayed and probabilistic outcomes (e.g., money, food, drugs), but relatively few studies have examined how people discount other commodities (e.g., entertainment, sex). Using a novel discounting task, where the length of a line represented the value of an outcome and was adjusted using a staircase procedure, we replicated previous findings showing that individuals discount delayed and probabilistic outcomes in a manner well described by a hyperbola-like function. In addition, we found strong positive correlations between discounting rates of delayed, but not probabilistic, outcomes. This suggests that discounting of delayed outcomes may be relatively predictable across outcome types but that discounting of probabilistic outcomes may depend more on specific contexts. The generality of delay discounting and potential context dependence of probability discounting may provide important information regarding factors contributing to choice behavior.
NASA Technical Reports Server (NTRS)
Grantham, William D.; Smith, Paul M.; Person, Lee H., Jr.; Meyer, Robert T.; Tingas, Stephen A.
1987-01-01
A piloted simulation study was conducted to determine the permissible time delay in the flight control system of a 10-percent statically unstable transport airplane during cruise flight conditions. The math model used for the simulation was a derivative Lockheed L-1011 wide-body jet transport. Data were collected and analyzed from a total of 137 cruising flights in both calm- and turbulent-air conditions. Results of this piloted simulation study verify previous findings that show present military specifications for allowable control-system time delay may be too stringent when applied to transport-size airplanes. Also, the degree of handling-qualities degradation due to time delay is shown to be strongly dependent on the source of the time delay in an advanced flight control system. Maximum allowable time delay for each source of time delay in the control system, in addition to a less stringent overall maximum level of time delay, should be considered for large aircraft. Preliminary results also suggest that adverse effects of control-system time delay may be at least partially offset by variations in control gearing. It is recommended that the data base include different airplane baselines, control systems, and piloting tasks with many pilots participating, so that a reasonable set of limits for control-system time delay can be established to replace the military specification limits currently being used.
Sheng, Duo; Lai, Hsiu-Fan; Chan, Sheng-Min; Hong, Min-Rong
2015-02-13
An all-digital on-chip delay sensor (OCDS) circuit with high delay-measurement resolution and low supply-voltage sensitivity for efficient detection and diagnosis in high-performance electronic system applications is presented. Based on the proposed delay measurement scheme, the quantization resolution of the proposed OCDS can be reduced to several picoseconds. Additionally, the proposed cascade-stage delay measurement circuit can enhance immunity to supply-voltage variations of the delay measurement resolution without extra self-biasing or calibration circuits. Simulation results show that the delay measurement resolution can be improved to 1.2 ps; the average delay resolution variation is 0.55% with supply-voltage variations of ±10%. Moreover, the proposed delay sensor can be implemented in an all-digital manner, making it very suitable for high-performance electronic system applications as well as system-level integration.
Study to design and develop remote manipulator system. [computer simulation of human performance
NASA Technical Reports Server (NTRS)
Hill, J. W.; Mcgovern, D. E.; Sword, A. J.
1974-01-01
Modeling of human performance in remote manipulation tasks is reported by automated procedures using computers to analyze and count motions during a manipulation task. Performance is monitored by an on-line computer capable of measuring the joint angles of both master and slave and in some cases the trajectory and velocity of the hand itself. In this way the operator's strategies with different transmission delays, displays, tasks, and manipulators can be analyzed in detail for comparison. Some progress is described in obtaining a set of standard tasks and difficulty measures for evaluating manipulator performance.
Optical system design for a Lunar Optical Interferometer
NASA Technical Reports Server (NTRS)
Colavita, M. M.; Shao, M.; Hines, B. E.; Levine, B. M.; Gershman, R.
1991-01-01
The moon offers particular advantages for interferometry, including a vacuum environment, a large stable base on which to assemble multi-kilometer baselines, and a cold nighttime temperature to allow for passive cooling of optics for high IR sensitivity. A baseline design for a Lunar Optical Interferometer (LOI) which exploits these features is presented. The instrument operates in the visible to mid-IL region, and is designed for both astrometry and synthesis imaging. The design uses a Y-shaped array of 12 siderostats, with maximum arm lengths of about 1 km. The inner siderostats are monitored in three dimensions from a central laser metrology structure to allow for high precision astrometry. The outer siderostats, used primarily for synthesis imaging, exploit the availability of bright reference stars in order to determine the instrument geometry. The path delay function is partitioned into coarse and fine components, the former accomplished with switched banks of range mirrors monitored with an absolute laser metrology system, and the latter with a short cat's eye delay line. The back end of the instrument is modular, allowing for beam combiners for astrometry, visible and IR synthesis imaging, and direct planet detection. With 1 m apertures, the instrument will have a point-source imaging sensitivity of about 29 mag; with the laser metrology system, astrometry at the microarcsecond level will be possible.
Using a new discretization approach to design a delayed LQG controller
NASA Astrophysics Data System (ADS)
Haraguchi, M.; Hu, H. Y.
2008-07-01
In general, discrete-time controls have become more and more preferable in engineering because of their easy implementation and simple computations. However, the available discretization approaches for the systems having time delays increase the system dimensions and have a high computational cost. This paper presents an effective discretization approach for the continuous-time systems with an input delay. The approach enables one to transform the input-delay system into a delay-free system, but retain the system dimensions unchanged in the state transformation. To demonstrate an application of the approach, this paper presents the design of an LQ regulator for continuous-time systems with an input delay and gives a state observer with a Kalman filter for estimating the full-state vector from some measurements of the system as well. The case studies in the paper well support the efficacy and efficiency of the proposed approach applied to the vibration control of a three-story structure model with the actuator delay taken into account.
Mechanisms for Adjusting Interaural Time Differences to Achieve Binaural Coincidence Detection
Seidl, Armin H.; Rubel, Edwin W; Harris, David M.
2010-01-01
Understanding binaural perception requires detailed analyses of the neural circuitry responsible for the computation of interaural time differences (ITDs). In the avian brainstem, this circuit consists of internal axonal delay lines innervating an array of coincidence detector neurons that encode external ITDs. Nucleus magnocellularis (NM) neurons project to the dorsal dendritic field of the ipsilateral nucleus laminaris (NL) and to the ventral field of the contralateral NL. Contralateral-projecting axons form a delay line system along a band of NL neurons. Binaural acoustic signals in the form of phase-locked action potentials from NM cells arrive at NL and establish a topographic map of sound source location along the azimuth. These pathways are assumed to represent a circuit similar to the Jeffress model of sound localization, establishing a place code along an isofrequency contour of NL. Three-dimensional measurements of axon lengths reveal major discrepancies with the current model; the temporal offset based on conduction length alone makes encoding of physiological ITDs impossible. However, axon diameter and distances between Nodes of Ranvier also influence signal propagation times along an axon. Our measurements of these parameters reveal that diameter and internode distance can compensate for the temporal offset inferred from axon lengths alone. Together with other recent studies these unexpected results should inspire new thinking on the cellular biology, evolution and plasticity of the circuitry underlying low frequency sound localization in both birds and mammals. PMID:20053889
NASA Astrophysics Data System (ADS)
Hrdlička, Aleš; Hegrová, Jitka; Novotný, Karel; Kanický, Viktor; Prochazka, David; Novotný, Jan; Modlitbová, Pavlína; Sládková, Lucia; Pořízka, Pavel; Kaiser, Jozef
2018-04-01
A LIBS equipment operating at 532 nm was optimized and used for sulfur determination in concrete samples. The influence of He atmosphere in a gas-tight chamber (1000-200 mbar) on S I 921.29 nm line sensitivity, signal-to-background and signal-to-noise ratio was studied at gate delays 100-2000 ns. Wide range of gate delays from 500 to about 1000 ns and pressures from several hundreds of mbar to the atmospheric pressure can be used for the desired detection of sulfur. The LIBS quantification was done using a simple calibration method. A synthetic limestone enriched by defined amounts of sodium sulfate was newly employed for direct quantification of S in concrete. This powder material was pressed into pellets and ablated with the LIBS system. The average content of sulfur as SO3 in the samples was 0.41-0.70 wt% by LIBS and 0.43-0.61 wt% by a reference standard procedure employing gravimetry and Inductively Coupled Plasma Triple Quad Mass Spectrometry (ICP-QQQMS). The uncertainty of the yielded LIBS results covers also the dispersion of the points in the calibration line and ranges from 16 to 28% at the probability level of 95%. The uncertainty of the ICP-QQQMS results was almost 10%. No correction on different signal response on the limestone and on the concrete was necessary.
Martin, Matthew J; Eberlein, Cath; Taylor, Molly; Ashton, Susan; Robinson, David; Cross, Darren
2016-12-27
Metabolic plasticity is an emerging hallmark of cancer, and increased glycolysis is often observed in transformed cells. Small molecule inhibitors that target driver oncogenes can potentially inhibit the glycolytic pathway. Osimertinib (AZD9291) is a novel EGFR tyrosine kinase inhibitor (TKI) that is potent and selective for sensitising (EGFRm) and T790M resistance mutations. Clinical studies have shown osimertinib to be efficacious in patients with EGFRm/ T790M advanced NSCLC who have progressed after EGFR-TKI treatment. However experience with targeted therapies suggests that acquired resistance may emerge. Thus there is a need to characterize resistance mechanisms and to devise ways to prevent, delay or overcome osimertinib resistance. We show here that osimertinib suppresses glycolysis in parental EGFR-mutant lung adenocarcinoma lines, but has not in osimertinib-resistant cell lines. Critically, we show osimertinib treatment induces a strict dependence on mitochondrial oxidative phosphorylation (OxPhos), as OxPhos inhibitors significantly delay the long-term development of osimertinib resistance in osimertinib-sensitive lines. Accordingly, growth conditions which promote a less glycolytic phenotype confer a degree of osimertinib resistance. Our data support a model in which the combination of osimertinib and OxPhos inhibitors can delay or prevent resistance in osimertinib-naïve tumour cells, and represents a novel strategy that warrants further pre-clinical investigation.
Martin, Matthew J.; Eberlein, Cath; Taylor, Molly; Ashton, Susan; Robinson, David; Cross, Darren
2016-01-01
Metabolic plasticity is an emerging hallmark of cancer, and increased glycolysis is often observed in transformed cells. Small molecule inhibitors that target driver oncogenes can potentially inhibit the glycolytic pathway. Osimertinib (AZD9291) is a novel EGFR tyrosine kinase inhibitor (TKI) that is potent and selective for sensitising (EGFRm) and T790M resistance mutations. Clinical studies have shown osimertinib to be efficacious in patients with EGFRm/ T790M advanced NSCLC who have progressed after EGFR-TKI treatment. However experience with targeted therapies suggests that acquired resistance may emerge. Thus there is a need to characterize resistance mechanisms and to devise ways to prevent, delay or overcome osimertinib resistance. We show here that osimertinib suppresses glycolysis in parental EGFR-mutant lung adenocarcinoma lines, but has not in osimertinib-resistant cell lines. Critically, we show osimertinib treatment induces a strict dependence on mitochondrial oxidative phosphorylation (OxPhos), as OxPhos inhibitors significantly delay the long-term development of osimertinib resistance in osimertinib-sensitive lines. Accordingly, growth conditions which promote a less glycolytic phenotype confer a degree of osimertinib resistance. Our data support a model in which the combination of osimertinib and OxPhos inhibitors can delay or prevent resistance in osimertinib-naïve tumour cells, and represents a novel strategy that warrants further pre-clinical investigation. PMID:27861144
NASA Astrophysics Data System (ADS)
Lan, Sheng; Sugimoto, Yoshimasa; Nishikawa, Satoshi; Ikeda, Naoki; Yang, Tao; Kanamoto, Kozyo; Ishikawa, Hiroshi; Asakawa, Kiyoshi
2002-07-01
We present a systematic study of coupled defects in photonic crystals (PCs) and explore their applications in constructing optical components and devices for ultrafast all-optical signal processing. First, we find that very deep band gaps can be generated in the impurity bands of coupled cavity waveguides (CCWs) by a small periodic modulation of defect modes. This phenomenon implies a high-efficiency all-optical switching mechanism. The switching mechanism can be easily extended from one-dimensional (1D) to two-dimensional and three-dimensional PC structures by utilizing the coupling of defect pairs which are generally present in PCs. Second, we suggest that CCWs with quasiflat and narrow impurity bands can be employed as efficient delay lines for ultrashort pulses. Criteria for designing such kind of CCWs have been derived from the analysis of defect coupling and the investigation of pulse transmission through various CCWs. It is found that the availability of quasiflat impurity bands depends not only on the intrinsic properties of the constituting defects but also on the detailed configuration of CCWs. In experiments, optical delay lines based on 1D monorail CCWs have been successfully fabricated and characterized. Finally, we have proposed a new mechanism for constructing waveguide intersections with broad bandwidth and low cross-talk.
Wide-Field Imaging Interferometry Spatial-Spectral Image Synthesis Algorithms
NASA Technical Reports Server (NTRS)
Lyon, Richard G.; Leisawitz, David T.; Rinehart, Stephen A.; Memarsadeghi, Nargess; Sinukoff, Evan J.
2012-01-01
Developed is an algorithmic approach for wide field of view interferometric spatial-spectral image synthesis. The data collected from the interferometer consists of a set of double-Fourier image data cubes, one cube per baseline. These cubes are each three-dimensional consisting of arrays of two-dimensional detector counts versus delay line position. For each baseline a moving delay line allows collection of a large set of interferograms over the 2D wide field detector grid; one sampled interferogram per detector pixel per baseline. This aggregate set of interferograms, is algorithmically processed to construct a single spatial-spectral cube with angular resolution approaching the ratio of the wavelength to longest baseline. The wide field imaging is accomplished by insuring that the range of motion of the delay line encompasses the zero optical path difference fringe for each detector pixel in the desired field-of-view. Each baseline cube is incoherent relative to all other baseline cubes and thus has only phase information relative to itself. This lost phase information is recovered by having point, or otherwise known, sources within the field-of-view. The reference source phase is known and utilized as a constraint to recover the coherent phase relation between the baseline cubes and is key to the image synthesis. Described will be the mathematical formalism, with phase referencing and results will be shown using data collected from NASA/GSFC Wide-Field Imaging Interferometry Testbed (WIIT).
Laut, Kristina Grønborg; Hjort, Jacob; Engstrøm, Thomas; Jensen, Lisette Okkels; Tilsted Hansen, Hans-Henrik; Jensen, Jan Skov; Pedersen, Frants; Jørgensen, Erik; Holmvang, Lene; Pedersen, Alma Becic; Christensen, Erika Frischknecht; Lippert, Freddy; Lang-Jensen, Torsten; Jans, Henning; Hansen, Poul Anders; Trautner, Sven; Kristensen, Steen Dalby; Lassen, Jens Flensted; Lash, Timothy L; Clemmensen, Peter; Terkelsen, Christian Juhl
2014-12-15
System delay (delay from emergency medical service call to reperfusion with primary percutaneous coronary intervention [PPCI]) is acknowledged as a performance measure in ST-elevation myocardial infarction (STEMI), as shorter system delay is associated with lower mortality. It is unknown whether system delay also impacts ability to stay in the labor market. Therefore, the aim of the study was to evaluate whether system delay is associated with duration of absence from work or time to retirement from work among patients with STEMI treated with PPCI. We conducted a population-based cohort study including patients ≤67 years of age who were admitted with STEMI from January 1, 1999, to December 1, 2011 and treated with PPCI. Data were derived from Danish population-based registries. Only patients who were full- or part-time employed before their STEMI admission were included. Association between system delay and time to return to the labor market was analyzed using a competing-risk regression analysis. Association between system delay and time to retirement from work was analyzed using a Cox regression model. A total of 4,061 patients were included. Ninety-three percent returned to the labor market during 4 years of follow-up, and 41% retired during 8 years of follow-up. After adjustment, system delay >120 minutes was associated with reduced resumption of work (subhazard ratio 0.86, 95% confidence interval 0.81 to 0.92) and earlier retirement from work (hazard ratio 1.21, 95% confidence interval 1.08 to 1.36). In conclusion, system delay was associated with reduced work resumption and earlier retirement. This highlights the value of system delay as a performance measure in treating patients with STEMI. Copyright © 2014 Elsevier Inc. All rights reserved.
Elemental misinterpretation in automated analysis of LIBS spectra.
Hübert, Waldemar; Ankerhold, Georg
2011-07-01
In this work, the Stark effect is shown to be mainly responsible for wrong elemental allocation by automated laser-induced breakdown spectroscopy (LIBS) software solutions. Due to broadening and shift of an elemental emission line affected by the Stark effect, its measured spectral position might interfere with the line position of several other elements. The micro-plasma is generated by focusing a frequency-doubled 200 mJ pulsed Nd/YAG laser on an aluminum target and furthermore on a brass sample in air at atmospheric pressure. After laser pulse excitation, we have measured the temporal evolution of the Al(II) ion line at 281.6 nm (4s(1)S-3p(1)P) during the decay of the laser-induced plasma. Depending on laser pulse power, the center of the measured line is red-shifted by 130 pm (490 GHz) with respect to the exact line position. In this case, the well-known spectral line positions of two moderate and strong lines of other elements coincide with the actual shifted position of the Al(II) line. Consequently, a time-resolving software analysis can lead to an elemental misinterpretation. To avoid a wrong interpretation of LIBS spectra in automated analysis software for a given LIBS system, we recommend using larger gate delays incorporating Stark broadening parameters and using a range of tolerance, which is non-symmetric around the measured line center. These suggestions may help to improve time-resolving LIBS software promising a smaller probability of wrong elemental identification and making LIBS more attractive for industrial applications.
Nulling at the Keck Interferometer
NASA Technical Reports Server (NTRS)
Colavita, M. Mark; Serabyn, Gene; Wizinowich, Peter L.; Akeson, Rachel L.
2006-01-01
The nulling mode of the Keck Interferometer is being commissioned at the Mauna Kea summit. The nuller combines the two Keck telescope apertures in a split-pupil mode to both cancel the on-axis starlight and to coherently detect the residual signal. The nuller, working at 10 um, is tightly integrated with the other interferometer subsystems including the fringe and angle trackers, the delay lines and laser metrology, and the real-time control system. Since first 10 um light in August 2004, the system integration is proceeding with increasing functionality and performance, leading to demonstration of a 100:1 on-sky null in 2005. That level of performance has now been extended to observations with longer coherent integration times. An overview of the overall system is presented, with emphasis on the observing sequence, phasing system, and differences with respect to the V2 system, along with a presentation of some recent engineering data.
NASA Astrophysics Data System (ADS)
Fuller, S. J.; Wragg, F. P. H.; Nutter, J.; Kalberer, M.
2014-08-01
Atmospheric aerosol particle concentrations have been linked with a wide range of pulmonary and cardio-vascular diseases but the particle properties responsible for these negative health effects are largely unknown. It is often speculated that reactive oxygen species (ROS) present in atmospheric particles lead to oxidative stress in, and ultimately disease of, the human lung. The quantification of ROS is highly challenging because some ROS components such as radicals are highly reactive and therefore short-lived. Thus, fast analysis methods are likely advantageous over methods with a long delay between aerosol sampling and ROS analysis. We present for the first time a detailed comparison of conventional off-line and fast on-line methods to quantify ROS in organic aerosols. For this comparison a new and fast on-line instrument was built and characterized to quantify ROS in aerosol particles with high sensitivity and a limit of detection of 4 nmol H2O2 equivalents per m3 air. ROS concentrations are measured with a time resolution of approximately 15 min, which allows the tracking of fast changing atmospheric conditions. The comparison of the off-line and on-line method shows that, in oxidized organic model aerosol particles, the majority of ROS have a very short lifetime of a few minutes whereas a small fraction is stable for a day or longer. This indicates that off-line techniques, where there is often a delay of hours to days between particle collection and ROS analysis, may severely underestimate true ROS concentrations and that fast on-line techniques are necessary for a reliable ROS quantification in atmospheric aerosol particles and a meaningful correlation with health outcomes.
Line scanning system for direct digital chemiluminescence imaging of DNA sequencing blots
DOE Office of Scientific and Technical Information (OSTI.GOV)
Karger, A.E.; Weiss, R.; Gesteland, R.F.
A cryogenically cooled charge-coupled device (CCD) camera equipped with an area CCD array is used in a line scanning system for low-light-level imaging of chemiluminescent DNA sequencing blots. Operating the CCD camera in time-delayed integration (TDI) mode results in continuous data acquisition independent of the length of the CCD array. Scanning is possible with a resolution of 1.4 line pairs/mm at the 50% level of the modulation transfer function. High-sensitivity, low-light-level scanning of chemiluminescent direct-transfer electrophoresis (DTE) DNA sequencing blots is shown. The detection of DNA fragments on the blot involves DNA-DNA hybridization with oligonucleotide-alkaline phosphatase conjugate and 1,2-dioxetane-based chemiluminescence.more » The width of the scan allows the recording of up to four sequencing reactions (16 lanes) on one scan. The scan speed of 52 cm/h used for the sequencing blots corresponds to a data acquisition rate of 384 pixels/s. The chemiluminescence detection limit on the scanned images is 3.9 [times] 10[sup [minus]18] mol of plasmid DNA. A conditional median filter is described to remove spikes caused by cosmic ray events from the CCD images. 39 refs., 9 refs.« less
Distinguishing fissions of 232Th, 237Np and 238U with beta-delayed gamma rays
Iyengar, A.; Norman, E. B.; Howard, C.; ...
2013-04-08
Measurements of beta-delayed gamma-ray spectra following 14-MeV neutron-induced fissions of 232Th, 238U, and 237Np were conducted at Lawrence Berkeley National Laboratory’s 88-Inch Cyclotron. Spectra were collected for times ranging from 1 minute to 14 hours after irradiation. Lastly, intensity ratios of gamma-ray lines were extracted from the data that allow identification of the fissioning isotope.
NASA Astrophysics Data System (ADS)
Bernard, D.; Serot, O.; Simon, E.; Boucher, L.; Plumeri, S.
2018-01-01
The photon interrogation analysis is a nondestructive technique allowing to identify and quantify fissile materials in nuclear waste packages. This paper details an automatic procedure which has been developed to simulate the delayed γ-ray spectra for several actinide photofissions. This calculation tool will be helpful for the fine conception (collimation, shielding, noise background optimizations, etc.) and for the on-line analysis of such a facility.
MSW (Magnetostatic Wave) Variable Time-Delay Techniques.
1983-09-01
will be releasable to the general public, including foreign nations. RADC-TR-83-139 has been reviewed and is approved for publication. APPROVED: 4...film carries by itself an infinite set of modes ( exchange effects being ignored). In the absence of ground planes, the secular equation for a single... exchange (3 2 ) * spin waves, which produces regularly spaced narrow-band absorbtions or "notches" in the delay line transmission response. This effect is
Irregularities and Forecast Studies of Equatorial Spread
2016-07-13
less certain and requires investigation. It should be possible to observe the Faraday rotation of the signals received at Jicamarca. This is another...indication of the line-integrated electron number 9 DISTRIBUTION A: Distribution approved for public release. density. Like the phase delay, the Faraday ...angle is a modulo-two-pi quantity that is best used to constrain the time evolution of the ionosphere. Both the Faraday angle and the phase delay are
NASA Astrophysics Data System (ADS)
Ikhsan, Siregar; Ulina Anastasia Sipangkar, Tri; Prasetio, Aji
2017-09-01
This research was conducted at a make to order production system company which is engaged in the car body of the vehicle. One of the products produced is dump truck which is one kind of transportation for the transport of goods equipped with hydraulics to facilitate goods’ loading and unloading process. The company has 7 work stations with different cycle times. Companies often experience delays in order delivery. The production process on the production floor has not been done optimally where there is a build up of work in process in some work centres. The build up of work in process (WIP) products is seen in the welding and painting stations. Stacking that occurs on the production line may cause the company to be liable for damages due to delays in product completion. The WIP occurs due to unbalanced paths can be seen from the variance of cycle time of each station is very diverse. The time difference of each work element is due to the allocation of work elements to each work centre unevenly. On the basis of the allocation of uneven work elements, the dump truck assembly line is made. The analysis is done by using Moodie Young and Comsoal method to do the balancing of production line. The result of layout improvement by using systematic layout planning (SLP) method is change the composition of the work centre from 7 into 4 work centre which enables the movement of material to be more effective and efficient so that it can get an efficient and effective production trajectory and can solve existing problems. The result of the track balancing is then used as a guide in constructing a new layout based on the balancing result with the most optimum method.
Measuring Ultrasonic Acoustic Velocity in a Thin Sheet of Graphite Epoxy Composite
NASA Technical Reports Server (NTRS)
2008-01-01
A method for measuring the acoustic velocity in a thin sheet of a graphite epoxy composite (GEC) material was investigated. This method uses two identical acoustic-emission (AE) sensors, one to transmit and one to receive. The delay time as a function of distance between sensors determines a bulk velocity. A lightweight fixture (balsa wood in the current implementation) provides a consistent method of positioning the sensors, thus providing multiple measurements of the time delay between sensors at different known distances. A linear fit to separation, x, versus delay time, t, will yield an estimate of the velocity from the slope of the line.
NASA Astrophysics Data System (ADS)
Bindhaiq, Salem; Zulkifli, Nadiatulhuda; Supa'at, AbuSahmah M.
2016-07-01
Time and wavelength-division multiplexed passive optical network (TWDM-PON) has been finally selected as the pragmatic solution for the next-generation passive optical network stage 2 (NG-PON2). In this paper, we propose a symmetric 40 Gb/s TWDM-PON system with low cost reflective semiconductor optical amplifier (RSOA) for both downstream and upstream directions. A single bi-pass delay interferometer (DI), deployed in the optical line terminal (OLT), is used to enhance the poor performance of the RSOA with respect to the low bandwidth induced by laser chirp. With the help of the 40 GHz free spectrum range (FSR) DI, we show a successful transmission of the proposed work through simulation study where an aggregate capacity of 40 Gb/s is transported over 40 km transmission distance with 32 splits. The TWDM-PON system at BER of 10-6 has shown a minimum receiver sensitivity of -22.78 dBm and -22.71 dBm for both downstream and upstream, respectively with maximum power penalty of 2 dB for downstream channel and 2.39 dB for upstream channel.
Integrated RF/Optical Interplanetary Networking Preliminary Explorations and Empirical Results
NASA Technical Reports Server (NTRS)
Raible, Daniel E.; Hylton, Alan G.
2012-01-01
Over the last decade interplanetary telecommunication capabilities have been significantly expanded--specifically in support of the Mars exploration rover and lander missions. NASA is continuing to drive advances in new, high payoff optical communications technologies to enhance the network to Gbps performance from Mars, and the transition from technology demonstration to operational system is examined through a hybrid RF/optical approach. Such a system combines the best features of RF and optical communications considering availability and performance to realize a dual band trunk line operating within characteristic constraints. Disconnection due to planetary obscuration and solar conjunction, link delays, timing, ground terminal mission congestion and scheduling policy along with space and atmospheric weather disruptions all imply the need for network protocol solutions to ultimately manage the physical layer in a transparent manner to the end user. Delay Tolerant Networking (DTN) is an approach under evaluation which addresses these challenges. A multi-hop multi-path hybrid RF and optical test bed has been constructed to emulate the integrated deep space network and to support protocol and hardware refinement. Initial experimental results characterize several of these challenges and evaluate the effectiveness of DTN as a solution to mitigate them.
A micro-epidemic model for primary dengue infection
NASA Astrophysics Data System (ADS)
Mishra, Arti; Gakkhar, Sunita
2017-06-01
In this paper, a micro-epidemic non-linear dynamical model has been proposed and analyzed for primary dengue infection. The model incorporates the effects of T cells immune response as well as humoral response during pathogenesis of dengue infection. The time delay has been accounted for production of antibodies from B cells. The basic reproduction number (R0) has been computed. Three equilibrium states are obtained. The existence and stability conditions for infection-free and ineffective cellular immune response state have been discussed. The conditions for existence of endemic state have been obtained. Further, the parametric region is obtained where system exhibits complex behavior. The threshold value of time delay has been computed which is critical for change in stability of endemic state. A threshold level for antibodies production rate has been obtained over which the infection will die out even though R0 > 1. The model is in line with the clinical observation that viral load decreases within 7-14 days from the onset of primary infection.
A Self-Synchronized Optoelectronic Oscillator based on an RTD Photo-Detector and a Laser Diode
Romeira, Bruno; Seunarine, Kris; Ironside, Charles N.; Kelly, Anthony E.; Figueiredo, José M. L.
2013-01-01
We propose and demonstrate a simple and stable low-phase noise optoelectronic oscillator (OEO) that uses a laser diode, an optical fiber delay line and a resonant tunneling diode (RTD) free-running oscillator that is monolithic integrated with a waveguide photo-detector. The RTD-OEO exhibits single-side band phase noise power below −100 dBc/Hz with more than 30 dB noise suppression at 10 kHz from the center free-running frequency for fiber loop lengths around 1.2 km. The oscillator power consumption is below 0.55 W, and can be controlled either by the injected optical power or the fiber delay line. The RTD-OEO stability is achieved without using other high-speed optical/optoelectronic components and amplification. PMID:23814452
Acousto-Optic Adaptive Processing (AOAP).
1983-12-01
2.03 mm 136 mm 41.6 mm Dense Flint Glass .58 1.06 48.6 21.7 LiNbO3 .65 2.24 250 46 1011 1 -: PbMoO4 .207 1.25 84.3 25.3 .- Slow Shear TeO2 .0586...mm 41.6 m Dense Flint Glass 5.9 1.06 3.2 21.7 LiNbO3 6.6 2.24 16.3 46 PbMoO4 2.1 1.25 5.5 25.6 TeO2 ’" ’" (slow,•...: Shear) 0.59 0.21 0.15 4.32 It is...was observed. 3.1.3 Delay Line The delay line used for the initial experiment is an Isomet Type 1201 AO modulator. This is a glass unit operat- ing at
Coherent correlator and equalizer using a reconfigurable all-optical tapped delay line.
Chitgarha, Mohammad Reza; Khaleghi, Salman; Yilmaz, Omer F; Tur, Moshe; Haney, Michael W; Langrock, Carsten; Fejer, Martin M; Willner, Alan E
2013-07-01
We experimentally demonstrate a reconfigurable optical tapped delay line in conjunction with coherent detection to search multiple patterns among quadrature phase shift keying (QPSK) symbols in 20 Gbaud data channel and also to equalize 20 and 31 Gbaud QPSK, 20 Gbaud 8 phase shift keying (PSK), and 16 QAM signals. Multiple patterns are searched successfully on QPSK signals, and correlation peaks are obtained at the matched patterns. QPSK, 8 PSK, and 16 QAM signals are also successfully recovered after 25 km of SMF-28 with average EVMs of 8.3%, 8.9%, and 7.8%. A penalty of <1 dB optical signal to noise penalty is achieved for a 20 Gbaud QPSK signal distorted by up to 400 ps/nm dispersion.
48 CFR 42.1304 - Government delay of work.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Government delay of work. 42.1304 Section 42.1304 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION... Government Delay of Work 42.1304 Government delay of work. (a) The clause at 52.242-17, Government Delay of...
48 CFR 42.1304 - Government delay of work.
Code of Federal Regulations, 2014 CFR
2014-10-01
... 48 Federal Acquisition Regulations System 1 2014-10-01 2014-10-01 false Government delay of work. 42.1304 Section 42.1304 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION... Government Delay of Work 42.1304 Government delay of work. (a) The clause at 52.242-17, Government Delay of...
NASA Astrophysics Data System (ADS)
Lu, Jianbo; Li, Dewei; Xi, Yugeng
2013-07-01
This article is concerned with probability-based constrained model predictive control (MPC) for systems with both structured uncertainties and time delays, where a random input delay and multiple fixed state delays are included. The process of input delay is governed by a discrete-time finite-state Markov chain. By invoking an appropriate augmented state, the system is transformed into a standard structured uncertain time-delay Markov jump linear system (MJLS). For the resulting system, a multi-step feedback control law is utilised to minimise an upper bound on the expected value of performance objective. The proposed design has been proved to stabilise the closed-loop system in the mean square sense and to guarantee constraints on control inputs and system states. Finally, a numerical example is given to illustrate the proposed results.
NASA Astrophysics Data System (ADS)
Zuwei, Zhang; Zhiyu, Wen; Jing, Hu
2012-04-01
The design and simulation of a novel microoptoelectromechanical system (MOEMS) accelerometer based on Raman—Nath diffraction are presented. The device is planned to be fabricated by microelectromechanical system technology and has a different sensing principle than the other reported MOEMS accelerometers. The fundamental theories and principles of the device are discussed in detail, a 3D finite element simulation of the flexural plate wave delay line oscillator is provided, and the operation frequency around 40 MHz is calculated. Finally, a lecture experiment is performed to demonstrate the feasibility of the device. This novel accelerometer is proposed to have the advantages of high sensitivity and anti-radiation, and has great potential for various applications.
High rate science data handling on Space Station Freedom
NASA Technical Reports Server (NTRS)
Handley, Thomas H., Jr.; Masline, Richard C.
1990-01-01
A study by NASA's User Information System Working Group for Space Station Freedom (SSF) has determined that the proposed onboard Data Management System, as initially configured, will be incapable of handling the data-generation rates typical of numerous scientific sensor payloads; many of these generate data at rates in excess of 10 Mbps, and there are at least four cases of rates in excess of 300 Mbps. The SSF Working Group has accordingly suggested an alternative conceptual architecture based on technology expected to achieve space-qualified status by 1995. The architecture encompasses recorders with rapid data-ingest capabilities and massive storage capabilities, optical delay lines allowing the recording of only the phenomena of interest, and data flow-compressing image processors.
Physics Goals for the Planned Next Linear Collider Engineering Test Facility
NASA Astrophysics Data System (ADS)
Raubenheimer, T. O.
2001-10-01
The Next Linear Collider (NLC) Collaboration is planning to construct an Engineering Test Facility (ETF) at Fermilab. As presently envisioned, the ETF would comprise a fundamental unit of the NLC main linac to include X-band klystrons and modulators, a delay-line power-distribution system (DLDS), and NLC accelerating structures that serve as loads. The principal purpose of the ETF is to validate stable operation of the power-distribution system, first without beam, then with a beam having the NLC pulse structure. This paper concerns the possibility of configuring and using the ETF to accelerate beam with an NLC pulse structure, as well as of doing experiments to measure beam-induced wakefields in the rf structures and their influence back on the beam.
Thermal Signature Identification System (TheSIS)
NASA Technical Reports Server (NTRS)
Merritt, Scott; Bean, Brian
2015-01-01
We characterize both nonlinear and high order linear responses of fiber-optic and optoelectronic components using spread spectrum temperature cycling methods. This Thermal Signature Identification System (TheSIS) provides much more detail than conventional narrowband or quasi-static temperature profiling methods. This detail allows us to match components more thoroughly, detect subtle reversible shifts in performance, and investigate the cause of instabilities or irreversible changes. In particular, we create parameterized models of athermal fiber Bragg gratings (FBGs), delay line interferometers (DLIs), and distributed feedback (DFB) lasers, then subject the alternative models to selection via the Akaike Information Criterion (AIC). Detailed pairing of components, e.g. FBGs, is accomplished by means of weighted distance metrics or norms, rather than on the basis of a single parameter, such as center wavelength.
Chhantyal-Pun, Rabi; Valavanis, Alexander; Keeley, James T; Rubino, Pierluigi; Kundu, Iman; Han, Yingjun; Dean, Paul; Li, Lianhe; Davies, A Giles; Linfield, Edmund H
2018-05-15
We demonstrate a gas spectroscopy technique, using self-mixing in a 3.4 terahertz quantum-cascade laser (QCL). All previous QCL spectroscopy techniques have required additional terahertz instrumentation (detectors, mixers, or spectrometers) for system pre-calibration or spectral analysis. By contrast, our system self-calibrates the laser frequency (i.e., with no external instrumentation) to a precision of 630 MHz (0.02%) by analyzing QCL voltage perturbations in response to optical feedback within a 0-800 mm round-trip delay line. We demonstrate methanol spectroscopy by introducing a gas cell into the feedback path and show that a limiting absorption coefficient of ∼1×10 -4 cm -1 is resolvable.
Size reduction techniques for vital compliant VHDL simulation models
Rich, Marvin J.; Misra, Ashutosh
2006-08-01
A method and system select delay values from a VHDL standard delay file that correspond to an instance of a logic gate in a logic model. Then the system collects all the delay values of the selected instance and builds super generics for the rise-time and the fall-time of the selected instance. Then, the system repeats this process for every delay value in the standard delay file (310) that correspond to every instance of every logic gate in the logic model. The system then outputs a reduced size standard delay file (314) containing the super generics for every instance of every logic gate in the logic model.
Structural Properties and Estimation of Delay Systems. Ph.D. Thesis
NASA Technical Reports Server (NTRS)
Kwong, R. H. S.
1975-01-01
Two areas in the theory of delay systems were studied: structural properties and their applications to feedback control, and optimal linear and nonlinear estimation. The concepts of controllability, stabilizability, observability, and detectability were investigated. The property of pointwise degeneracy of linear time-invariant delay systems is considered. Necessary and sufficient conditions for three dimensional linear systems to be made pointwise degenerate by delay feedback were obtained, while sufficient conditions for this to be possible are given for higher dimensional linear systems. These results were applied to obtain solvability conditions for the minimum time output zeroing control problem by delay feedback. A representation theorem is given for conditional moment functionals of general nonlinear stochastic delay systems, and stochastic differential equations are derived for conditional moment functionals satisfying certain smoothness properties.
Stochastic parameter estimation in nonlinear time-delayed vibratory systems with distributed delay
NASA Astrophysics Data System (ADS)
Torkamani, Shahab; Butcher, Eric A.
2013-07-01
The stochastic estimation of parameters and states in linear and nonlinear time-delayed vibratory systems with distributed delay is explored. The approach consists of first employing a continuous time approximation to approximate the delayed integro-differential system with a large set of ordinary differential equations having stochastic excitations. Then the problem of state and parameter estimation in the resulting stochastic ordinary differential system is represented as an optimal filtering problem using a state augmentation technique. By adapting the extended Kalman-Bucy filter to the augmented filtering problem, the unknown parameters of the time-delayed system are estimated from noise-corrupted, possibly incomplete measurements of the states. Similarly, the upper bound of the distributed delay can also be estimated by the proposed technique. As an illustrative example to a practical problem in vibrations, the parameter, delay upper bound, and state estimation from noise-corrupted measurements in a distributed force model widely used for modeling machine tool vibrations in the turning operation is investigated.
Robust stability bounds for multi-delay networked control systems
NASA Astrophysics Data System (ADS)
Seitz, Timothy; Yedavalli, Rama K.; Behbahani, Alireza
2018-04-01
In this paper, the robust stability of a perturbed linear continuous-time system is examined when controlled using a sampled-data networked control system (NCS) framework. Three new robust stability bounds on the time-invariant perturbations to the original continuous-time plant matrix are presented guaranteeing stability for the corresponding discrete closed-loop augmented delay-free system (ADFS) with multiple time-varying sensor and actuator delays. The bounds are differentiated from previous work by accounting for the sampled-data nature of the NCS and for separate communication delays for each sensor and actuator, not a single delay. Therefore, this paper expands the knowledge base in multiple inputs multiple outputs (MIMO) sampled-data time delay systems. Bounds are presented for unstructured, semi-structured, and structured perturbations.
Time delays in flight simulator visual displays
NASA Technical Reports Server (NTRS)
Crane, D. F.
1980-01-01
It is pointed out that the effects of delays of less than 100 msec in visual displays on pilot dynamic response and system performance are of particular interest at this time because improvements in the latest computer-generated imagery (CGI) systems are expected to reduce CGI displays delays to this range. Attention is given to data which quantify the effects of display delays in the range of 0-100 msec on system stability and performance, and pilot dynamic response for a particular choice of aircraft dynamics, display, controller, and task. The conventional control system design methods are reviewed, the pilot response data presented, and data for long delays, all suggest lead filter compensation of display delay. Pilot-aircraft system crossover frequency information guides compensation filter specification.
The use of photonic techniques in tunable microwave oscillators
NASA Astrophysics Data System (ADS)
Madziar, K.; Szymańska, A.; Galwas, B.
2013-07-01
In this paper, we present opportunities to use photonic techniques in tuning process of opto-electronic oscillators. These opportunities involve wavelength controlled delay lines and fiber Bragg gratings.
Effects of intrinsic stochasticity on delayed reaction-diffusion patterning systems.
Woolley, Thomas E; Baker, Ruth E; Gaffney, Eamonn A; Maini, Philip K; Seirin-Lee, Sungrim
2012-05-01
Cellular gene expression is a complex process involving many steps, including the transcription of DNA and translation of mRNA; hence the synthesis of proteins requires a considerable amount of time, from ten minutes to several hours. Since diffusion-driven instability has been observed to be sensitive to perturbations in kinetic delays, the application of Turing patterning mechanisms to the problem of producing spatially heterogeneous differential gene expression has been questioned. In deterministic systems a small delay in the reactions can cause a large increase in the time it takes a system to pattern. Recently, it has been observed that in undelayed systems intrinsic stochasticity can cause pattern initiation to occur earlier than in the analogous deterministic simulations. Here we are interested in adding both stochasticity and delays to Turing systems in order to assess whether stochasticity can reduce the patterning time scale in delayed Turing systems. As analytical insights to this problem are difficult to attain and often limited in their use, we focus on stochastically simulating delayed systems. We consider four different Turing systems and two different forms of delay. Our results are mixed and lead to the conclusion that, although the sensitivity to delays in the Turing mechanism is not completely removed by the addition of intrinsic noise, the effects of the delays are clearly ameliorated in certain specific cases.
Jahn, Beate; Theurl, Engelbert; Siebert, Uwe; Pfeiffer, Karl-Peter
2010-01-01
In most decision-analytic models in health care, it is assumed that there is treatment without delay and availability of all required resources. Therefore, waiting times caused by limited resources and their impact on treatment effects and costs often remain unconsidered. Queuing theory enables mathematical analysis and the derivation of several performance measures of queuing systems. Nevertheless, an analytical approach with closed formulas is not always possible. Therefore, simulation techniques are used to evaluate systems that include queuing or waiting, for example, discrete event simulation. To include queuing in decision-analytic models requires a basic knowledge of queuing theory and of the underlying interrelationships. This tutorial introduces queuing theory. Analysts and decision-makers get an understanding of queue characteristics, modeling features, and its strength. Conceptual issues are covered, but the emphasis is on practical issues like modeling the arrival of patients. The treatment of coronary artery disease with percutaneous coronary intervention including stent placement serves as an illustrative queuing example. Discrete event simulation is applied to explicitly model resource capacities, to incorporate waiting lines and queues in the decision-analytic modeling example.
Ratchagit, Kreangkri
2007-10-01
In this paper, we derive a sufficient condition for asymptotic stability of the zero solution of delay-difference system of Hopfield neural networks in terms of certain matrix inequalities by using a discrete version of the Lyapunov second method. The result is applied to obtain new asymptotic stability condition for some class of delay-difference system such as delay-difference system of Hopfield neural networks with multiple delays in terms of certain matrix inequalities. Our results can be well suited for computational purposes.
Stability and Bifurcation Analysis in a Maglev System with Multiple Delays
NASA Astrophysics Data System (ADS)
Zhang, Lingling; Huang, Jianhua; Huang, Lihong; Zhang, Zhizhou
This paper considers the time-delayed feedback control for Maglev system with two discrete time delays. We determine constraints on the feedback time delays which ensure the stability of the Maglev system. An algorithm is developed for drawing a two-parametric bifurcation diagram with respect to two delays τ1 and τ2. Direction and stability of periodic solutions are also determined using the normal form method and center manifold theory by Hassard. The complex dynamical behavior of the Maglev system near the domain of stability is confirmed by exhaustive numerical simulation.
Elitzur, Tomer; Yakir, Esther; Quansah, Lydia; Zhangjun, Fei; Vrebalov, Julia; Khayat, Eli; Giovannoni, James J.
2016-01-01
Genetic solutions to postharvest crop loss can reduce cost and energy inputs while increasing food security, especially for banana (Musa acuminata), which is a significant component of worldwide food commerce. We have functionally characterized two banana E class (SEPALLATA3 [SEP3]) MADS box genes, MaMADS1 and MaMADS2, homologous to the tomato (Solanum lycopersicum) RIN-MADS ripening gene. Transgenic banana plants repressing either gene (via antisense or RNA interference [RNAi]) were created and exhibited specific ripening delay and extended shelf-life phenotypes, including delayed color development and softening. The delay in fruit ripening is associated with a delay in climacteric respiration and reduced synthesis of the ripening hormone ethylene; in the most severe repressed lines, no ethylene was produced and ripening was most delayed. Unlike tomato rin mutants, banana fruits of all transgenic repression lines responded to exogenous ethylene by ripening normally, likely due to incomplete transgene repression and/or compensation by other MADS box genes. Our results show that, although MADS box ripening gene necessity is conserved across diverse taxa (monocots to dicots), unlike tomato, banana ripening requires at least two necessary members of the SEPALLATA MADS box gene group, and either can serve as a target for ripening control. The utility of such genes as tools for ripening control is especially relevant in important parthenocarpic crops such as the vegetatively propagated and widely consumed Cavendish banana, where breeding options for trait improvement are severely limited. PMID:26956665
Elitzur, Tomer; Yakir, Esther; Quansah, Lydia; Zhangjun, Fei; Vrebalov, Julia; Khayat, Eli; Giovannoni, James J; Friedman, Haya
2016-05-01
Genetic solutions to postharvest crop loss can reduce cost and energy inputs while increasing food security, especially for banana (Musa acuminata), which is a significant component of worldwide food commerce. We have functionally characterized two banana E class (SEPALLATA3 [SEP3]) MADS box genes, MaMADS1 and MaMADS2, homologous to the tomato (Solanum lycopersicum) RIN-MADS ripening gene. Transgenic banana plants repressing either gene (via antisense or RNA interference [RNAi]) were created and exhibited specific ripening delay and extended shelf-life phenotypes, including delayed color development and softening. The delay in fruit ripening is associated with a delay in climacteric respiration and reduced synthesis of the ripening hormone ethylene; in the most severe repressed lines, no ethylene was produced and ripening was most delayed. Unlike tomato rin mutants, banana fruits of all transgenic repression lines responded to exogenous ethylene by ripening normally, likely due to incomplete transgene repression and/or compensation by other MADS box genes. Our results show that, although MADS box ripening gene necessity is conserved across diverse taxa (monocots to dicots), unlike tomato, banana ripening requires at least two necessary members of the SEPALLATA MADS box gene group, and either can serve as a target for ripening control. The utility of such genes as tools for ripening control is especially relevant in important parthenocarpic crops such as the vegetatively propagated and widely consumed Cavendish banana, where breeding options for trait improvement are severely limited. © 2016 American Society of Plant Biologists. All Rights Reserved.
Transfer of learned perception of sensorimotor simultaneity.
Pesavento, Michael J; Schlag, John
2006-10-01
Synchronizing a motor response to a predictable sensory stimulus, like a periodic flash or click, relies on feedback (somesthetic, auditory, visual, or other) from the motor response. Practically, this results in a small (<50 ms) asynchrony in which the motor response leads the sensory event. Here we show that the perceived simultaneity in a coincidence-anticipation task (line crossing) is affected by changing the perceived simultaneity in a different task (pacing). In the pace task, human subjects were instructed to press a key in perfect synchrony with a red square flashed every second. In training sessions, feedback was provided by flashing a blue square with each key press, below the red square. There were two types of training pace sessions: one in which the feedback was provided with no delay, the other (adapting), in which the feedback was progressively delayed (up to 100 ms). Subjects' asynchrony was unchanged in the first case, but it was significantly increased in the pace task with delay. In the coincidence-anticipation task, a horizontally moving vertical bar crossed a vertical line in the middle of a screen. Subjects were instructed to press a key exactly when the bar crossed the line. They were given no feedback on their performance. Asynchrony on the line-crossing task was tested after the training pace task with feedback. We found that this asynchrony to be significantly increased even though there never was any feedback on the coincidence-anticipation task itself. Subjects were not aware that their sensorimotor asynchrony had been lengthened (sometimes doubled). We conclude that perception of simultaneity in a sensorimotor task is learned. If this perception is caused by coincidence of signals in the brain, the timing of these signals depends on something-acquired by experience-more adaptable than physiological latencies.
Generating chaos for discrete time-delayed systems via impulsive control.
Guan, Zhi-Hong; Liu, Na
2010-03-01
Generating chaos for a class of discrete time-delayed systems via impulsive control is investigated in this paper. With the augmented matrix method, the time-delay impulsive systems can be transformed into a new class of linear discrete impulsive systems. Based on the largest Lyapunov exponent and the boundedness of the systems, some theoretical results about the chaotification for the discrete impulsive systems with time delay are derived and an example is given to visualize the satisfactory control performance.
Impact of delayed information in sub-second complex systems
NASA Astrophysics Data System (ADS)
Manrique, Pedro D.; Zheng, Minzhang; Johnson Restrepo, D. Dylan; Hui, Pak Ming; Johnson, Neil F.
What happens when you slow down the delivery of information in large-scale complex systems that operate faster than the blink of an eye? This question just adopted immediate commercial, legal and political importance following U.S. regulators' decision to allow an intentional 350 microsecond delay to be added in the ultrafast network of financial exchanges. However there is still no scientific understanding available to policymakers of the potential system-wide impact of such delays. Here we take a first step in addressing this question using a minimal model of a population of competing, heterogeneous, adaptive agents which has previously been shown to produce similar statistical features to real markets. We find that while certain extreme system-level behaviors can be prevented by such delays, the duration of others is increased. This leads to a highly non-trivial relationship between delays and system-wide instabilities which warrants deeper empirical investigation. The generic nature of our model suggests there should be a fairly wide class of complex systems where such delay-driven extreme behaviors can arise, e.g. sub-second delays in brain function possibly impacting individuals' behavior, and sub-second delays in navigational systems potentially impacting the safety of driverless vehicles.
NASA Astrophysics Data System (ADS)
Patel, K. C.; Ruiz, R.; Lille, J.; Wan, L.; Dobiz, E.; Gao, H.; Robertson, N.; Albrecht, T. R.
2012-03-01
Directed self-assembly is emerging as a promising technology to define sub-20nm features. However, a straightforward path to scale block copolymer lithography to single-digit fabrication remains challenging given the diverse material properties found in the wide spectrum of self-assembling materials. A vast amount of block copolymer research for industrial applications has been dedicated to polystyrene-b-methyl methacrylate (PS-b-PMMA), a model system that displays multiple properties making it ideal for lithography, but that is limited by a weak interaction parameter that prevents it from scaling to single-digit lithography. Other block copolymer materials have shown scalability to much smaller dimensions, but at the expense of other material properties that could delay their insertion into industrial lithographic processes. We report on a line doubling process applied to block copolymer patterns to double the frequency of PS-b-PMMA line/space features, demonstrating the potential of this technique to reach single-digit lithography. We demonstrate a line-doubling process that starts with directed self-assembly of PS-b-PMMA to define line/space features. This pattern is transferred into an underlying sacrificial hard-mask layer followed by a growth of self-aligned spacers which subsequently serve as hard-masks for transferring the 2x frequency doubled pattern to the underlying substrate. We applied this process to two different block copolymer materials to demonstrate line-space patterns with a half pitch of 11nm and 7nm underscoring the potential to reach single-digit critical dimensions. A subsequent patterning step with perpendicular lines can be used to cut the fine line patterns into a 2-D array of islands suitable for bit patterned media. Several integration challenges such as line width control and line roughness are addressed.
Role of p53 in cdk Inhibitor VMY-1-103-induced Apoptosis in Prostate Cancer
2013-11-01
DAOY medulloblastoma cells, which have a p53 mutation (6). In order to examine if this holds true in prostate cancer cell lines, I stably transfected...disrupts chromosome organization and delays metaphase progression in medulloblastoma cells. Cancer Biol Ther. 2011 Nov 1;12(9):818-26 Other...1-103 is a novel CDK inhibitor that disrupts chromosome organization and delays metaphase progression in medulloblastoma cells. Cancer Biol Ther
A loose bolt delays loading of Endeavour's external tank
NASA Technical Reports Server (NTRS)
2000-01-01
This view shows the pipe (center top) leading toward Endeavour from the side of the White Room at Launch Pad 39B. A loose bracket observed hanging down from the pipe delayed loading of Endeavour's external tank by several hours to allow technicians to remove it. A 'U' bolt connects the bracket to a fire suppression water line attached to the exterior of the White Room. The loose bolt could have possibly created a debris hazard.
ERIC Educational Resources Information Center
Smith, Erin; McLaughlin, T. F.; Neyman, Jennifer; Rinaldi, Lisa
2013-01-01
This study was designed to examine the effects of tracing and fading prompts to improve the handwriting of two preschoolers both diagnosed as Developmentally Delayed (DD) and one of whom had fine motor goals. The study took place in a self-contained special education public preschool classroom located in the Pacific Northwest. The results showed…
OTACT: ONU Turning with Adaptive Cycle Times in Long-Reach PONs
NASA Astrophysics Data System (ADS)
Zare, Sajjad; Ghaffarpour Rahbar, Akbar
2015-01-01
With the expansion of PON networks as Long-Reach PON (LR-PON) networks, the problem of degrading the efficiency of centralized bandwidth allocation algorithms threatens this network due to high propagation delay. This is because these algorithms are based on bandwidth negotiation messages frequently exchanged between the optical line terminal (OLT) in the Central Office and optical network units (ONUs) near the users, which become seriously delayed when the network is extended. To solve this problem, some decentralized algorithms are proposed based on bandwidth negotiation messages frequently exchanged between the Remote Node (RN)/Local Exchange (LX) and ONUs near the users. The network has a relatively high delay since there are relatively large distances between RN/LX and ONUs, and therefore, control messages should travel twice between ONUs and RN/LX in order to go from one ONU to another ONU. In this paper, we propose a novel framework, called ONU Turning with Adaptive Cycle Times (OTACT), that uses Power Line Communication (PLC) to connect two adjacent ONUs. Since there is a large population density in urban areas, ONUs are closer to each other. Thus, the efficiency of the proposed method is high. We investigate the performance of the proposed scheme in contrast with other decentralized schemes under the worst case conditions. Simulation results show that the average upstream packet delay can be decreased under the proposed scheme.
NASA Technical Reports Server (NTRS)
Luck, R.; Ray, A.
1988-01-01
A method for compensating the effects of network-induced delays in integrated communication and control systems (ICCS) is proposed, and a finite-dimensional time-invariant ICCS model is developed. The problem of analyzing systems with time-varying and stochastic delays is circumvented by the application of a deterministic observer. For the case of controller-to-actuator delays, the observed design must rely on an extended model which represents the delays as additional states.
Delays in the operating room: signs of an imperfect system.
Wong, Janice; Khu, Kathleen Joy; Kaderali, Zul; Bernstein, Mark
2010-06-01
Delays in the operating room have a negative effect on its efficiency and the working environment. In this prospective study, we analyzed data on perioperative system delays. One neurosurgeon prospectively recorded all errors, including perioperative delays, for consecutive patients undergoing elective procedures from May 2000 to February 2009. We analyzed the prevalence, causes and impact of perioperative system delays that occurred in one neurosurgeon's practice. A total of 1531 elective surgical cases were performed during the study period. Delays were the most common type of error (33.6%), and more than half (51.4%) of all cases had at least 1 delay. The most common cause of delay was equipment failure. The first cases of the day and cranial cases had more delays than subsequent cases and spinal cases, respectively. A delay in starting the first case was associated with subsequent delays. Delays frequently occur in the operating room and have a major effect on patient flow and resource utilization. Thorough documentation of perioperative delays provides a basis for the development of solutions for improving operating room efficiency and illustrates the principles underlying the causes of operating room delays across surgical disciplines.
A system and method for online high-resolution mapping of gastric slow-wave activity.
Bull, Simon H; O'Grady, Gregory; Du, Peng; Cheng, Leo K
2014-11-01
High-resolution (HR) mapping employs multielectrode arrays to achieve spatially detailed analyses of propagating bioelectrical events. A major current limitation is that spatial analyses must currently be performed "off-line" (after experiments), compromising timely recording feedback and restricting experimental interventions. These problems motivated development of a system and method for "online" HR mapping. HR gastric recordings were acquired and streamed to a novel software client. Algorithms were devised to filter data, identify slow-wave events, eliminate corrupt channels, and cluster activation events. A graphical user interface animated data and plotted electrograms and maps. Results were compared against off-line methods. The online system analyzed 256-channel serosal recordings with no unexpected system terminations with a mean delay 18 s. Activation time marking sensitivity was 0.92; positive predictive value was 0.93. Abnormal slow-wave patterns including conduction blocks, ectopic pacemaking, and colliding wave fronts were reliably identified. Compared to traditional analysis methods, online mapping had comparable results with equivalent coverage of 90% of electrodes, average RMS errors of less than 1 s, and CC of activation maps of 0.99. Accurate slow-wave mapping was achieved in near real-time, enabling monitoring of recording quality and experimental interventions targeted to dysrhythmic onset. This work also advances the translation of HR mapping toward real-time clinical application.
NASA Astrophysics Data System (ADS)
Klein, R.; Adler, A.; Beanlands, R. S.; de Kemp, R. A.
2007-02-01
A rubidium-82 (82Rb) elution system is described for use with positron emission tomography. Due to the short half-life of 82Rb (76 s), the system physics must be modelled precisely to account for transport delay and the associated activity decay and dispersion. Saline flow is switched between a 82Sr/82Rb generator and a bypass line to achieve a constant-activity elution of 82Rb. Pulse width modulation (PWM) of a solenoid valve is compared to simple threshold control as a means to simulate a proportional valve. A predictive-corrective control (PCC) algorithm is developed which produces a constant-activity elution within the constraints of long feedback delay and short elution time. The system model parameters are adjusted through a self-tuning algorithm to minimize error versus the requested time-activity profile. The system is self-calibrating with 2.5% repeatability, independent of generator activity and elution flow rate. Accurate 30 s constant-activity elutions of 10-70% of the total generator activity are achieved using both control methods. The combined PWM-PCC method provides significant improvement in precision and accuracy of the requested elution profiles. The 82Rb elution system produces accurate and reproducible constant-activity elution profiles of 82Rb activity, independent of parent 82Sr activity in the generator. More reproducible elution profiles may improve the quality of clinical and research PET perfusion studies using 82Rb.
Klein, R; Adler, A; Beanlands, R S; Dekemp, R A
2007-02-07
A rubidium-82 ((82)Rb) elution system is described for use with positron emission tomography. Due to the short half-life of (82)Rb (76 s), the system physics must be modelled precisely to account for transport delay and the associated activity decay and dispersion. Saline flow is switched between a (82)Sr/(82)Rb generator and a bypass line to achieve a constant-activity elution of (82)Rb. Pulse width modulation (PWM) of a solenoid valve is compared to simple threshold control as a means to simulate a proportional valve. A predictive-corrective control (PCC) algorithm is developed which produces a constant-activity elution within the constraints of long feedback delay and short elution time. The system model parameters are adjusted through a self-tuning algorithm to minimize error versus the requested time-activity profile. The system is self-calibrating with 2.5% repeatability, independent of generator activity and elution flow rate. Accurate 30 s constant-activity elutions of 10-70% of the total generator activity are achieved using both control methods. The combined PWM-PCC method provides significant improvement in precision and accuracy of the requested elution profiles. The (82)Rb elution system produces accurate and reproducible constant-activity elution profiles of (82)Rb activity, independent of parent (82)Sr activity in the generator. More reproducible elution profiles may improve the quality of clinical and research PET perfusion studies using (82)Rb.
Rank One Strange Attractors in Periodically Kicked Predator-Prey System with Time-Delay
NASA Astrophysics Data System (ADS)
Yang, Wenjie; Lin, Yiping; Dai, Yunxian; Zhao, Huitao
2016-06-01
This paper is devoted to the study of the problem of rank one strange attractor in a periodically kicked predator-prey system with time-delay. Our discussion is based on the theory of rank one maps formulated by Wang and Young. Firstly, we develop the rank one chaotic theory to delayed systems. It is shown that strange attractors occur when the delayed system undergoes a Hopf bifurcation and encounters an external periodic force. Then we use the theory to the periodically kicked predator-prey system with delay, deriving the conditions for Hopf bifurcation and rank one chaos along with the results of numerical simulations.
Optimal estimation of parameters and states in stochastic time-varying systems with time delay
NASA Astrophysics Data System (ADS)
Torkamani, Shahab; Butcher, Eric A.
2013-08-01
In this study estimation of parameters and states in stochastic linear and nonlinear delay differential systems with time-varying coefficients and constant delay is explored. The approach consists of first employing a continuous time approximation to approximate the stochastic delay differential equation with a set of stochastic ordinary differential equations. Then the problem of parameter estimation in the resulting stochastic differential system is represented as an optimal filtering problem using a state augmentation technique. By adapting the extended Kalman-Bucy filter to the resulting system, the unknown parameters of the time-delayed system are estimated from noise-corrupted, possibly incomplete measurements of the states.
NASA Technical Reports Server (NTRS)
Brunstrom, Anna; Leutenegger, Scott T.; Simha, Rahul
1995-01-01
Traditionally, allocation of data in distributed database management systems has been determined by off-line analysis and optimization. This technique works well for static database access patterns, but is often inadequate for frequently changing workloads. In this paper we address how to dynamically reallocate data for partionable distributed databases with changing access patterns. Rather than complicated and expensive optimization algorithms, a simple heuristic is presented and shown, via an implementation study, to improve system throughput by 30 percent in a local area network based system. Based on artificial wide area network delays, we show that dynamic reallocation can improve system throughput by a factor of two and a half for wide area networks. We also show that individual site load must be taken into consideration when reallocating data, and provide a simple policy that incorporates load in the reallocation decision.
Time and position sensitive single photon detector for scintillator read-out
NASA Astrophysics Data System (ADS)
Schössler, S.; Bromberger, B.; Brandis, M.; Schmidt, L. Ph H.; Tittelmeier, K.; Czasch, A.; Dangendorf, V.; Jagutzki, O.
2012-02-01
We have developed a photon counting detector system for combined neutron and γ radiography which can determine position, time and intensity of a secondary photon flash created by a high-energy particle or photon within a scintillator screen. The system is based on a micro-channel plate photomultiplier concept utilizing image charge coupling to a position- and time-sensitive read-out anode placed outside the vacuum tube in air, aided by a standard photomultiplier and very fast pulse-height analyzing electronics. Due to the low dead time of all system components it can cope with the high throughput demands of a proposed combined fast neutron and dual discrete energy γ radiography method (FNDDER). We show tests with different types of delay-line read-out anodes and present a novel pulse-height-to-time converter circuit with its potential to discriminate γ energies for the projected FNDDER devices for an automated cargo container inspection system (ACCIS).
Distributed Optimal Consensus Control for Multiagent Systems With Input Delay.
Zhang, Huaipin; Yue, Dong; Zhao, Wei; Hu, Songlin; Dou, Chunxia; Huaipin Zhang; Dong Yue; Wei Zhao; Songlin Hu; Chunxia Dou; Hu, Songlin; Zhang, Huaipin; Dou, Chunxia; Yue, Dong; Zhao, Wei
2018-06-01
This paper addresses the problem of distributed optimal consensus control for a continuous-time heterogeneous linear multiagent system subject to time varying input delays. First, by discretization and model transformation, the continuous-time input-delayed system is converted into a discrete-time delay-free system. Two delicate performance index functions are defined for these two systems. It is shown that the performance index functions are equivalent and the optimal consensus control problem of the input-delayed system can be cast into that of the delay-free system. Second, by virtue of the Hamilton-Jacobi-Bellman (HJB) equations, an optimal control policy for each agent is designed based on the delay-free system and a novel value iteration algorithm is proposed to learn the solutions to the HJB equations online. The proposed adaptive dynamic programming algorithm is implemented on the basis of a critic-action neural network (NN) structure. Third, it is proved that local consensus errors of the two systems and weight estimation errors of the critic-action NNs are uniformly ultimately bounded while the approximated control policies converge to their target values. Finally, two simulation examples are presented to illustrate the effectiveness of the developed method.
Koch, Christian
2010-05-01
A technique for the calibration of photodiodes in ultrasonic measurement systems using standard and cost-effective optical and electronic components is presented. A heterodyne system was realized using two commercially available distributed feedback lasers, and the required frequency stability and resolution were ensured by a difference-frequency servo control scheme. The frequency-sensitive element generating the error signal for the servo loop comprised a delay-line discriminator constructed from electronic elements. Measurements were carried out at up to 450 MHz, and the uncertainties of about 5% (k = 2) can be further reduced by improved radio frequency power measurement without losing the feature of using only simple elements. The technique initially dedicated to the determination of the frequency response of photodetectors applied in ultrasonic applications can be transferred to other application fields of optical measurements.
NASA Technical Reports Server (NTRS)
Fouts, Douglas J.
1992-01-01
The design, implementation, testing, and applications of a gallium-arsenide digital phase shifter and fan-out buffer are described. The integrated circuit provides a method for adjusting the phase of high-speed clock and control signals in digital systems, without the need for pruning cables, multiplexing between cables of different lengths, delay lines, or similar techniques. The phase of signals distributed with the described chip can be dynamically adjusted in eight different steps of approximately 60 ps per step. The IC also serves as a fan-out buffer and provides 12 in-phase outputs. The chip is useful for distributing high-speed clock and control signals in synchronous digital systems, especially if components are distributed over a large physical area or if there is a large number of components.
Slowing light down by low magnetic fields: pulse delay by transient spectral hole-burning in ruby.
Riesen, Hans; Rebane, Aleksander K; Szabo, Alex; Carceller, Ivana
2012-08-13
We report on the observation of slow light induced by transient spectral hole-burning in a solid, that is based on excited-state population storage. Experiments were conducted in the R1-line (2E←4A2 transition) of a 2.3 mm thick pink ruby (Al2O3:Cr(III) 130 ppm). Importantly, the pulse delay can be controlled by the application of a low external magnetic field B||c≤9 mT and delays of up to 11 ns with minimal pulse distortion are observed for ~55 ns Gaussian pulses. The delay corresponds to a group velocity value of ~c/1400. The experiment is very well modelled by linear spectral filter theory and the results indicate the possibility of using transient hole-burning based slow light experiments as a spectroscopic technique.
Microlensing makes lensed quasar time delays significantly time variable
NASA Astrophysics Data System (ADS)
Tie, S. S.; Kochanek, C. S.
2018-01-01
The time delays of gravitationally lensed quasars are generally believed to be unique numbers whose measurement is limited only by the quality of the light curves and the models for the contaminating contribution of gravitational microlensing to the light curves. This belief is incorrect - gravitational microlensing also produces changes in the actual time delays on the ∼day(s) light-crossing time-scale of the emission region. This is due to a combination of the inclination of the disc relative to the line of sight and the differential magnification of the temperature fluctuations producing the variability. We demonstrate this both mathematically and with direct calculations using microlensing magnification patterns. Measuring these delay fluctuations can provide a physical scale for microlensing observations, removing the need for priors on either the microlens masses or the component velocities. That time delays in lensed quasars are themselves time variable likely explains why repeated delay measurements of individual lensed quasars appear to vary by more than their estimated uncertainties. This effect is also a new important systematic problem for attempts to use time delays in lensed quasars for cosmology or to detect substructures (satellites) in lens galaxies.
Preliminary Results of P & S-wave Teleseismic Tomography of the Superior Region
NASA Astrophysics Data System (ADS)
Bollmann, T. A.; van der Lee, S.; Frederiksen, A. W.
2013-12-01
In continental North America, the Midcontinent Rift System (MRS) is the most prominent feature in gravity and magnetic anomaly maps. These anomalies are associated with large amount of igneous material deposited there around 1.1 Ga. Preliminary evidence from ambient seismic noise analysis of the area has found that the MRS crustal structure has a low velocity along its axis. A major question remains as to whether any structural evidence for the MRS' rifting episodes or its failure were retained in the lithospheric mantle beneath it. To this end we measured teleseismic P and S travel times at Earthscope seismic stations from the Flexible Array SPREE, the Transportable Array, and several US ANSS Backbone stations. These measurements constitute a major resource for upgrading an existing teleseismic, pre-SPREE tomography model for the region, (Frederiksen et al., 2013) as well as longer wavelength regional models, such as NA07 (Bedle and Van der Lee, 2007). We measured the delay times of about 25 thousand teleseismic P arrivals from over a hundred events with magnitudes of 5.5 and greater, and about half as many for S arrivals. Nearly half of these teleseismic events are to the NNW (Alaska-Japan) and about one third are from Central and South America to the SSE. We inverted the P delays for common station-side delays and common event-side delays. Station-side P delays vary by about 1.5 s over the region, with the Archean Superior Craton recording earlier arrivals than Proterozoic terrains in Wisconsin. SPREE stations show later arrivals closer to the rift axis compare to earlier onesfurther away from the rift, but a correlation with the large rift-related gravity anomaly is not obvious. To examine whether the mantle has any rift-related structures, for example from meltdepletion, we are measuring delay times from additional events recorded and recovered during the spring SPREE service run, applying corrections to the delay times for topography and crustal structure, and will invert the corrected delay times for 3D mantle structure. The average P-wave delay time from all events for each station fit to a surface. An interpolated surface of these values is shown in the background. The gray lines are accretionary provinces from Whitmeyer & Karlstrom (2007).
Profitless delays for extinction in nonautonomous Lotka-Volterra system
NASA Astrophysics Data System (ADS)
Liu, Shengqiang; Chen, Lansun
2001-12-01
We study the delayed periodic n-species Lotka-Voterra systems where the growth rate of each species is not always positive. The sufficient conditions for the extinction that are independent of the delays are obtained. Some known results are improved and generalized. Our results suggest that under some conditions, the introduction and the variance of the time delays can be both harmless and profitless. Discussion about the effect of time delays on the extinction of the system is also advanced.
Recent results of nonlinear estimators applied to hereditary systems.
NASA Technical Reports Server (NTRS)
Schiess, J. R.; Roland, V. R.; Wells, W. R.
1972-01-01
An application of the extended Kalman filter to delayed systems to estimate the state and time delay is presented. Two nonlinear estimators are discussed and the results compared with those of the Kalman filter. For all the filters considered, the hereditary system was treated with the delay in the pure form and by using Pade approximations of the delay. A summary of the convergence properties of the filters studied is given. The results indicate that the linear filter applied to the delayed system performs inadequately while the nonlinear filters provide reasonable estimates of both the state and the parameters.
The acoustic sensor for rapid analysis of bacterial cells in the conductive suspensions.
Borodina, I A; Zaitsev, B D; Guliy, O; Teplykh, A A; Shikhabudinov, A M
2017-11-01
The possibility of using the acoustic sensor on the basis of a two-channel delay line for rapid analysis of bacterial cells in the conductive suspensions was investigated. The dependencies of change in phase and insertion loss of output signal of the sensor on conductivity of buffer solution with various concentrations of cells due to a specific interaction "bacterial cells - mini-antibodies" for electrically open and electrically shorted channels of delay line were measured. It has been found that these changes have the most values for the electrically open channel. It has been also shown that the sensor rapidly responds to the specific interaction and the time stabilization of the phase and insertion loss of output signal is less than 10min. Copyright © 2017 Elsevier B.V. All rights reserved.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Saito, Ryo; Naruko, Atsushi; Hiramatsu, Takashi
2014-10-01
In this paper, we introduce a new approach to a treatment of the gravitational effects (redshift, time delay and lensing) on the observed cosmic microwave background (CMB) anisotropies based on the Boltzmann equation. From the Liouville's theorem in curved spacetime, the intensity of photons is conserved along a photon geodesic when non-gravitational scatterings are absent. Motivated by this fact, we derive a second-order line-of-sight formula by integrating the Boltzmann equation along a perturbed geodesic (curve) instead of a background geodesic (line). In this approach, the separation of the gravitational and intrinsic effects are manifest. This approach can be considered asmore » a generalization of the remapping approach of CMB lensing, where all the gravitational effects can be treated on the same footing.« less
Frequency hopping due to acousto-electric interaction in ZnO based surface acoustic wave oscillator
NASA Astrophysics Data System (ADS)
Dasgupta, Daipayan; Sreenivas, K.
2011-08-01
A 36 MHz surface acoustic wave delay line based oscillator has been used to study the effect of acousto-electric interaction due to photo generated charge carriers in rf sputtered ZnO film under UV illumination (λ = 365 nm, 20-100 μW/cm2). Design aspects for developing a delay line based SAW oscillator are specified. The observed linear downshift in frequency (2.2 to 19.0 kHz) with varying UV intensity (20-100 μW/cm2) is related to the fractional velocity change due to acousto-electric interaction. UV illumination level of 100 μW/cm2 leads to a characteristic frequency hopping behavior arising due to a change in the oscillation criteria, and is attributed to the complex interplay between the increased attenuation and velocity shift.
Fleyer, Michael; Horowitz, Moshe
2018-04-02
We demonstrate, theoretically and experimentally, a new method to measure small changes in the cavity length of oscillators. The method is based on the high sensitivity of the phase of forced delay-line oscillators to changes in their cavity length. The oscillator phase is directly detected by mixing the oscillator output with the injected signal. We describe a comprehensive theoretical model for studying the signal and the noise at the output of a general forced delay-line oscillator with an instantaneous gain saturation and an amplitude-to-phase conversion. The results indicate that the magnitude and the bandwidth of the oscillator response to a small perturbation can be controlled by adjusting the injection ratio and the injected frequency. For signals with a frequency that is smaller than the device bandwidth, the oscillator noise is dominated by the noise of the injected signal. This noise is highly suppressed by mixing the oscillator output with the injected signal. Hence, the device sensitivity at frequencies below its bandwidth is limited only by the internal noise that is added in a single roundtrip in the oscillator cavity. We demonstrate the use of a forced oscillator as an acoustic fiber sensor in an optoelectronic oscillator. A good agreement is obtained between theory and experiments. The magnitude of the output signal can be controlled by adjusting the injection ratio while the noise power at low frequencies is not enhanced as in sensors that are based on a free-running oscillator.
Cross delay line sensor characterization
DOE Office of Scientific and Technical Information (OSTI.GOV)
Owens, Israel J; Remelius, Dennis K; Tiee, Joe J
There exists a wealth of information in the scientific literature on the physical properties and device characterization procedures for complementary metal oxide semiconductor (CMOS), charge coupled device (CCD) and avalanche photodiode (APD) format detectors. Numerous papers and books have also treated photocathode operation in the context of photomultiplier tube (PMT) operation for either non imaging applications or limited night vision capability. However, much less information has been reported in the literature about the characterization procedures and properties of photocathode detectors with novel cross delay line (XDL) anode structures. These allow one to detect single photons and create images by recordingmore » space and time coordinate (X, Y & T) information. In this paper, we report on the physical characteristics and performance of a cross delay line anode sensor with an enhanced near infrared wavelength response photocathode and high dynamic range micro channel plate (MCP) gain (> 10{sup 6}) multiplier stage. Measurement procedures and results including the device dark event rate (DER), pulse height distribution, quantum and electronic device efficiency (QE & DQE) and spatial resolution per effective pixel region in a 25 mm sensor array are presented. The overall knowledge and information obtained from XDL sensor characterization allow us to optimize device performance and assess capability. These device performance properties and capabilities make XDL detectors ideal for remote sensing field applications that require single photon detection, imaging, sub nano-second timing response, high spatial resolution (10's of microns) and large effective image format.« less
NASA Astrophysics Data System (ADS)
Grasso, R.; Gulino, M.; Scordino, A.; Musumeci, F.; Campisi, A.; Bonfanti, R.; Carbone, C.; Puglisi, G.
2016-05-01
The first results concerning the possibility to use Delayed Luminescence spectroscopy to evaluate the in vitro induction of cytotoxic effects on human glioblastoma cells of nanostructured lipid carrier and drug-loaded nanostructured lipid carrier are showed in this contribution. We tested the effects of nanostructured lipid carrier, ferulic acid and ferulic acidloaded nanostructured lipid carrier on U-87MG cell line. The study seems to confirm the ability of Delayed Luminescence to be sensible indicator of alterations induced on functionality of the mitochondrial respiratory chain complex I in U-87MG cancer cells when treated with nanostructured lipid carriers.
Molecular Basis of Cardiac Delayed Rectifier Potassium Channel Function and Pharmacology.
Wu, Wei; Sanguinetti, Michael C
2016-06-01
Human cardiomyocytes express 3 distinct types of delayed rectifier potassium channels. Human ether-a-go-go-related gene (hERG) channels conduct the rapidly activating current IKr; KCNQ1/KCNE1 channels conduct the slowly activating current IKs; and Kv1.5 channels conduct an ultrarapid activating current IKur. Here the authors provide a general overview of the mechanistic and structural basis of ion selectivity, gating, and pharmacology of the 3 types of cardiac delayed rectifier potassium ion channels. Most blockers bind to S6 residues that line the central cavity of the channel, whereas activators interact with the channel at 4 symmetric binding sites outside the cavity. Copyright © 2016 Elsevier Inc. All rights reserved.
An adaptive robust controller for time delay maglev transportation systems
NASA Astrophysics Data System (ADS)
Milani, Reza Hamidi; Zarabadipour, Hassan; Shahnazi, Reza
2012-12-01
For engineering systems, uncertainties and time delays are two important issues that must be considered in control design. Uncertainties are often encountered in various dynamical systems due to modeling errors, measurement noises, linearization and approximations. Time delays have always been among the most difficult problems encountered in process control. In practical applications of feedback control, time delay arises frequently and can severely degrade closed-loop system performance and in some cases, drives the system to instability. Therefore, stability analysis and controller synthesis for uncertain nonlinear time-delay systems are important both in theory and in practice and many analytical techniques have been developed using delay-dependent Lyapunov function. In the past decade the magnetic and levitation (maglev) transportation system as a new system with high functionality has been the focus of numerous studies. However, maglev transportation systems are highly nonlinear and thus designing controller for those are challenging. The main topic of this paper is to design an adaptive robust controller for maglev transportation systems with time-delay, parametric uncertainties and external disturbances. In this paper, an adaptive robust control (ARC) is designed for this purpose. It should be noted that the adaptive gain is derived from Lyapunov-Krasovskii synthesis method, therefore asymptotic stability is guaranteed.
Kerns, Q.A.
1963-08-01
>An electronlc circuit for synthesizing electrical current pulses having very fast rise times includes several sinewave generators tuned to progressively higher harmonic frequencies with signal amplitudes and phases selectable according to the Fourier series of the waveform that is to be synthesized. Phase control is provided by periodically triggering the generators at precisely controlled times. The outputs of the generators are combined in a coaxial transmission line. Any frequency-dependent delays that occur in the transmission line can be readily compensated for so that the desired signal wave shape is obtained at the output of the line. (AEC)
Reinforcement Learning Strategies for Clinical Trials in Non-small Cell Lung Cancer
Zhao, Yufan; Zeng, Donglin; Socinski, Mark A.; Kosorok, Michael R.
2010-01-01
Summary Typical regimens for advanced metastatic stage IIIB/IV non-small cell lung cancer (NSCLC) consist of multiple lines of treatment. We present an adaptive reinforcement learning approach to discover optimal individualized treatment regimens from a specially designed clinical trial (a “clinical reinforcement trial”) of an experimental treatment for patients with advanced NSCLC who have not been treated previously with systemic therapy. In addition to the complexity of the problem of selecting optimal compounds for first and second-line treatments based on prognostic factors, another primary goal is to determine the optimal time to initiate second-line therapy, either immediately or delayed after induction therapy, yielding the longest overall survival time. A reinforcement learning method called Q-learning is utilized which involves learning an optimal regimen from patient data generated from the clinical reinforcement trial. Approximating the Q-function with time-indexed parameters can be achieved by using a modification of support vector regression which can utilize censored data. Within this framework, a simulation study shows that the procedure can extract optimal regimens for two lines of treatment directly from clinical data without prior knowledge of the treatment effect mechanism. In addition, we demonstrate that the design reliably selects the best initial time for second-line therapy while taking into account the heterogeneity of NSCLC across patients. PMID:21385164
NASA Astrophysics Data System (ADS)
Tang, Xianhua; Cao, Daomin; Zou, Xingfu
We consider a periodic Lotka-Volterra competition system without instantaneous negative feedbacks (i.e., pure-delay systems) x(t)=x(t)[r(t)-∑j=1na(t)x(t-τ(t))], i=1,2,…,n. We establish some 3/2-type criteria for global attractivity of a positive periodic solution of the system, which generalize the well-known Wright's 3/2 criteria for the autonomous delay logistic equation, and thereby, address the open problem proposed by both Kuang [Y. Kuang, Global stability in delayed nonautonomous Lotka-Volterra type systems without saturated equilibria, Differential Integral Equations 9 (1996) 557-567] and Teng [Z. Teng, Nonautonomous Lotka-Volterra systems with delays, J. Differential Equations 179 (2002) 538-561].
Global solutions to the electrodynamic two-body problem on a straight line
NASA Astrophysics Data System (ADS)
Bauer, G.; Deckert, D.-A.; Dürr, D.; Hinrichs, G.
2017-06-01
The classical electrodynamic two-body problem has been a long standing open problem in mathematics. For motion constrained to the straight line, the interaction is similar to that of the two-body problem of classical gravitation. The additional complication is the presence of unbounded state-dependent delays in the Coulomb forces due to the finiteness of the speed of light. This circumstance renders the notion of local solutions meaningless, and therefore, straightforward ODE techniques cannot be applied. Here, we study the time-symmetric case, i.e., the Fokker-Schwarzschild-Tetrode (FST) equations, comprising both advanced and retarded delays. We extend the technique developed in Deckert and Hinrichs (J Differ Equ 260:6900-6929, 2016), where existence of FST solutions was proven on the half line, to ensure global existence—a result that had been obtained by Bauer (Ein Existenzsatz für die Wheeler-Feynman-Elektrodynamik, Herbert Utz Verlag, München, 1997). Due to the novel technique, the presented proof is shorter and more transparent but also relies on the idea to employ asymptotic data to characterize solutions.
Time-delayed feedback control of diffusion in random walkers.
Ando, Hiroyasu; Takehara, Kohta; Kobayashi, Miki U
2017-07-01
Time delay in general leads to instability in some systems, while specific feedback with delay can control fluctuated motion in nonlinear deterministic systems to a stable state. In this paper, we consider a stochastic process, i.e., a random walk, and observe its diffusion phenomenon with time-delayed feedback. As a result, the diffusion coefficient decreases with increasing delay time. We analytically illustrate this suppression of diffusion by using stochastic delay differential equations and justify the feasibility of this suppression by applying time-delayed feedback to a molecular dynamics model.
Exact synchronization bound for coupled time-delay systems.
Senthilkumar, D V; Pesquera, Luis; Banerjee, Santo; Ortín, Silvia; Kurths, J
2013-04-01
We obtain an exact bound for synchronization in coupled time-delay systems using the generalized Halanay inequality for the general case of time-dependent delay, coupling, and coefficients. Furthermore, we show that the same analysis is applicable to both uni- and bidirectionally coupled time-delay systems with an appropriate evolution equation for their synchronization manifold, which can also be defined for different types of synchronization. The exact synchronization bound assures an exponential stabilization of the synchronization manifold which is crucial for applications. The analytical synchronization bound is independent of the nature of the modulation and can be applied to any time-delay system satisfying a Lipschitz condition. The analytical results are corroborated numerically using the Ikeda system.
Spectral Structure Of Phase-Induced Intensity Noise In Recirculating Delay Lines
NASA Astrophysics Data System (ADS)
Tur, M.; Moslehi, B.; Bowers, J. E.; Newton, S. A.; Jackson, K. P.; Goodman, J. W.; Cutler, C. C.; Shaw, H. J.
1983-09-01
The dynamic range of fiber optic signal processors driven by relatively incoherent multimode semiconductor lasers is shown to be severely limited by laser phase-induced noise. It is experimentally demonstrated that while the noise power spectrum of differential length fiber filters is approximately flat, processors with recirculating loops exhibit noise with a periodically structured power spectrum with notches at zero frequency as well as at all other multiples of 1/(loop delay). The experimental results are aug-mented by a theoretical analysis.
Radiometer Testbed Development for SWOT
NASA Technical Reports Server (NTRS)
Kangaslahti, Pekka; Brown, Shannon; Gaier, Todd; Dawson, Douglas; Harding, Dennis; Fu, Lee-Lueng; Esteban-Fernandez, Daniel
2010-01-01
Conventional altimeters include nadir looking colocated 18-37 GHz microwave radiometer to measure wet tropospheric path delay. These have reduced accuracy in coastal zone (within 50 km from land) and do not provide wet path delay over land. The addition of high frequency channels to Jason-class radiometer will improve retrievals in coastal regions and enable retrievals over land. High-frequency window channels, 90, 130 and 166 GHz are optimum for improving performance in coastal region and channels on 183 GHz water vapor line are ideal for over-land retrievals.
Amplitude- and rise-time-compensated filters
Nowlin, Charles H.
1984-01-01
An amplitude-compensated rise-time-compensated filter for a pulse time-of-occurrence (TOOC) measurement system is disclosed. The filter converts an input pulse, having the characteristics of random amplitudes and random, non-zero rise times, to a bipolar output pulse wherein the output pulse has a zero-crossing time that is independent of the rise time and amplitude of the input pulse. The filter differentiates the input pulse, along the linear leading edge of the input pulse, and subtracts therefrom a pulse fractionally proportional to the input pulse. The filter of the present invention can use discrete circuit components and avoids the use of delay lines.
'Lead us not into temptation': adolescence and alcohol policy in Europe.
Hope, Ann
2014-01-01
Although the World Health Organization and the European Community recognize harm to children and young people due to alcohol-whether their own or someone else's drinking-effective policies to reduce harm are not widely followed. The alcohol beverage industry's drive to use social networking systems blurs the line between user-generated and industry marketing materials, such that young people are more frequently and at a younger age, potentially exposed to the promotion of alcoholic drinks. This contravenes recommendations arising out of the emerging scientific literature that delaying the onset of drinking and reducing the prevalence of heavy session drinking are likely to promote a healthier next generation.
Extended Range Passive Wireless Tag System and Method
NASA Technical Reports Server (NTRS)
Fink, Patrick W. (Inventor); Lin, Gregory Y. (Inventor); Kennedy, Timothy F. (Inventor)
2013-01-01
A passive wireless tag assembly comprises a plurality of antennas and transmission lines interconnected with circuitry and constructed and arranged in a Van Atta array or configuration to reflect an interrogator signal in the direction from where it came. The circuitry may comprise at least one surface acoustic wave (SAW)-based circuit that functions as a signal reflector and is operatively connected with an information circuit. In another embodiment, at least one delay circuit and/or at least one passive modulation circuit(s) are utilized. In yet another embodiment, antennas connected to SAW-based devices are mounted to at least one of the orthogonal surfaces of a corner reflector.
1990-05-01
L0341 K ISOLATE MALFUNCTIONS TO DIRECTIONAL COUPLERS - 6 L0436 A REMOVE OR REPLACE TWTS - 6 M0443 A ALIGN DELAY EQUALIZER COMPONENTS - 6 M0447 A ALIGN...CONTROLS - 6 L0390 A PERFORM OPERATIONAL TESTS ON RECEIVER TRANSMITTER CONTROLS - 6 LO0O1 A PERFORM PHIS ON TWT SHF TRANSMITTERS - 6 L0410 A REMOVE OR...REPLACE DIRECTIONAL COUPLERS - 6 L0420 A REMOVE OR REPLACE LINE VOLTAGE REGULATORS - 6 L0435 A REMOVE OR REPLACE TWT SHF TRANSMITTERS - 6 L0436 A
Optoelectronic Reservoir Computing
Paquot, Y.; Duport, F.; Smerieri, A.; Dambre, J.; Schrauwen, B.; Haelterman, M.; Massar, S.
2012-01-01
Reservoir computing is a recently introduced, highly efficient bio-inspired approach for processing time dependent data. The basic scheme of reservoir computing consists of a non linear recurrent dynamical system coupled to a single input layer and a single output layer. Within these constraints many implementations are possible. Here we report an optoelectronic implementation of reservoir computing based on a recently proposed architecture consisting of a single non linear node and a delay line. Our implementation is sufficiently fast for real time information processing. We illustrate its performance on tasks of practical importance such as nonlinear channel equalization and speech recognition, and obtain results comparable to state of the art digital implementations. PMID:22371825
Ionospheric Slant Total Electron Content Analysis Using Global Positioning System Based Estimation
NASA Technical Reports Server (NTRS)
Komjathy, Attila (Inventor); Mannucci, Anthony J. (Inventor); Sparks, Lawrence C. (Inventor)
2017-01-01
A method, system, apparatus, and computer program product provide the ability to analyze ionospheric slant total electron content (TEC) using global navigation satellite systems (GNSS)-based estimation. Slant TEC is estimated for a given set of raypath geometries by fitting historical GNSS data to a specified delay model. The accuracy of the specified delay model is estimated by computing delay estimate residuals and plotting a behavior of the delay estimate residuals. An ionospheric threat model is computed based on the specified delay model. Ionospheric grid delays (IGDs) and grid ionospheric vertical errors (GIVEs) are computed based on the ionospheric threat model.
NASA Astrophysics Data System (ADS)
Faria, Teresa; Oliveira, José J.
This paper addresses the local and global stability of n-dimensional Lotka-Volterra systems with distributed delays and instantaneous negative feedbacks. Necessary and sufficient conditions for local stability independent of the choice of the delay functions are given, by imposing a weak nondelayed diagonal dominance which cancels the delayed competition effect. The global asymptotic stability of positive equilibria is established under conditions slightly stronger than the ones required for the linear stability. For the case of monotone interactions, however, sharper conditions are presented. This paper generalizes known results for discrete delays to systems with distributed delays. Several applications illustrate the results.
Section 7 reactor incident file general information from 1945
DOE Office of Scientific and Technical Information (OSTI.GOV)
Not Available
1969-01-10
At 0308 on January 10, 1966, both B and C Reactors ``scrammed`` due to an electrical fault on Line C2-L8 caused by a raccoon coming in contact with the 13-8 KV line on top of transformer No. 2 at 182-B Building. Line C2-L8 relayed out at the 151-B Building. Details of the occurrence at 151-B are covered in the attachment. C-Reactor scrammed due to reduced voltage on the pressure monitor system. The reduction in voltage caused the auxiliary relays of the pressure monitor ground detector to open, de-energizing the end result relays PSR and PSRA. The safety circuit trip identificationmore » system displayed ``Pressure Monitor`` and ``Ground Detector.`` B-Reactor scrammed by a power failure signal from 190-B Building. The power failure relays for pump numbers 1 and 3 opened due to these pumps contributing power to the fault. The power failure relays at 190-B remained open long enough for the end result relays PF and PFA to open. Since these relays are timed delayed, 0.26 seconds, the power failure relays must have remained open at least that long. At the 190-B Building the steam turbines started due to the power failure relays for pump numbers 1 and 3 opening. The main process pumps remained stable and continued to supply normal flow to the reactor. Pumps were tripped from the line at 182-B and 183-B Buildings. The surge suppressors cycled normally and the turbine export pumps started as a result of low export line pressure. No power equipment was affected in C Area.« less
NASA Astrophysics Data System (ADS)
Korshunov, G. I.; Afanasev, P. I.; Bulbasheva, I. A.
2017-10-01
The monitoring and survey results of drilling and blasting operations are specified during the development of Afanasyevsky deposit of cement raw materials for a 110 kV electricity power lines structure. Seismic explosion waves and air shock waves were registered in the course of monitoring. The dependency of peak particle velocities on the scaled distance and explosive weight by the delay time was obtained.
Focused shock spark discharge drill using multiple electrodes
Moeny, William M.; Small, James G.
1988-01-01
A spark discharge focused drill provided with one pulse forming line or a number of pulse forming lines. The pulse forming line is connected to an array of electrodes which would form a spark array. One of the electrodes of each of the array is connected to the high voltage side of the pulse forming line and the other electrodes are at ground potential. When discharged in a liquid, these electrodes produce intense focused shock waves that can pulverize or fracture rock. By delaying the firing of each group of electrodes, the drill can be steered within the earth. Power can be fed to the pulse forming line either downhole or from the surface area. A high voltage source, such as a Marx generator, is suitable for pulse charging the lines.
Delay-dependent coupling for a multi-agent LTI consensus system with inter-agent delays
NASA Astrophysics Data System (ADS)
Qiao, Wei; Sipahi, Rifat
2014-01-01
Delay-dependent coupling (DDC) is considered in this paper in a broadly studied linear time-invariant multi-agent consensus system in which agents communicate with each other under homogeneous delays, while attempting to reach consensus. The coupling among the agents is designed here as an explicit parameter of this delay, allowing couplings to autonomously adapt based on the delay value, and in order to guarantee stability and a certain degree of robustness in the network despite the destabilizing effect of delay. Design procedures, analysis of convergence speed of consensus, comprehensive numerical studies for the case of time-varying delay, and limitations are presented.
Delay correlation analysis and representation for vital complaint VHDL models
Rich, Marvin J.; Misra, Ashutosh
2004-11-09
A method and system unbind a rise/fall tuple of a VHDL generic variable and create rise time and fall time generics of each generic variable that are independent of each other. Then, according to a predetermined correlation policy, the method and system collect delay values in a VHDL standard delay file, sort the delay values, remove duplicate delay values, group the delay values into correlation sets, and output an analysis file. The correlation policy may include collecting all generic variables in a VHDL standard delay file, selecting each generic variable, and performing reductions on the set of delay values associated with each selected generic variable.
NASA Astrophysics Data System (ADS)
Argibay-Losada, Pablo Jesus; Sahin, Gokhan
2014-08-01
Random access memories (RAM) are fundamental in conventional electronic switches and routers to manage short-term congestion and to decrease data loss probabilities. Switches in all-optical networks (AONs), however, do not have access to optical RAM, and therefore are prone to much higher loss levels than their electronic counterparts. Fiber-delay-lines (FDLs), able to delay an optical data packet a fixed amount of time, have been proposed in the literature as a means to alleviate those high loss levels. However, they are extremely bulky to manage, so their usage introduces a trade-off between practicality and performance in the design and operation of the AON. In this paper we study the influence that FDLs have in the performance of flows crossing an all-optical switch that acts as their bottleneck. We show how extremely low numbers of FDLs (e.g., 1 or 2) can help in reducing losses by several orders of magnitude in several illustrative scenarios with high aggregation levels. Our results therefore suggest that FDLs can be a practical means of dealing with congestion in AONs in the absence of optical RAM buffers or of suitable data interchange protocols specifically designed for AONs.
A system for the measurement of delayed neutrons and gammas from special nuclear materials
Andrews, M. T.; Corcoran, E. C.; Goorley, J. T.; ...
2014-11-27
The delayed neutron counting (DNC) system at the Royal Military College of Canada has been upgraded to accommodate concurrent delayed neutron and gamma measurements. This delayed neutron and gamma counting (DNGC) system uses a SLOWPOKE-2 reactor to irradiate fissile materials before their transfer to a counting arrangement consisting of six ³He and one HPGe detector. The application of this system is demonstrated in an example where delayed neutron and gamma emissions are used in complement to examine ²³³U content and determine fissile mass with an average relative error and accuracy of -2.2 and 1.5 %, respectively.
Maximum principle for a stochastic delayed system involving terminal state constraints.
Wen, Jiaqiang; Shi, Yufeng
2017-01-01
We investigate a stochastic optimal control problem where the controlled system is depicted as a stochastic differential delayed equation; however, at the terminal time, the state is constrained in a convex set. We firstly introduce an equivalent backward delayed system depicted as a time-delayed backward stochastic differential equation. Then a stochastic maximum principle is obtained by virtue of Ekeland's variational principle. Finally, applications to a state constrained stochastic delayed linear-quadratic control model and a production-consumption choice problem are studied to illustrate the main obtained result.
NASA Astrophysics Data System (ADS)
Yuan, Jinlong; Zhang, Xu; Liu, Chongyang; Chang, Liang; Xie, Jun; Feng, Enmin; Yin, Hongchao; Xiu, Zhilong
2016-09-01
Time-delay dynamical systems, which depend on both the current state of the system and the state at delayed times, have been an active area of research in many real-world applications. In this paper, we consider a nonlinear time-delay dynamical system of dha-regulonwith unknown time-delays in batch culture of glycerol bioconversion to 1,3-propanediol induced by Klebsiella pneumonia. Some important properties and strong positive invariance are discussed. Because of the difficulty in accurately measuring the concentrations of intracellular substances and the absence of equilibrium points for the time-delay system, a quantitative biological robustness for the concentrations of intracellular substances is defined by penalizing a weighted sum of the expectation and variance of the relative deviation between system outputs before and after the time-delays are perturbed. Our goal is to determine optimal values of the time-delays. To this end, we formulate an optimization problem in which the time delays are decision variables and the cost function is to minimize the biological robustness. This optimization problem is subject to the time-delay system, parameter constraints, continuous state inequality constraints for ensuring that the concentrations of extracellular and intracellular substances lie within specified limits, a quality constraint to reflect operational requirements and a cost sensitivity constraint for ensuring that an acceptable level of the system performance is achieved. It is approximated as a sequence of nonlinear programming sub-problems through the application of constraint transcription and local smoothing approximation techniques. Due to the highly complex nature of this optimization problem, the computational cost is high. Thus, a parallel algorithm is proposed to solve these nonlinear programming sub-problems based on the filled function method. Finally, it is observed that the obtained optimal estimates for the time-delays are highly satisfactory via numerical simulations.
On Time Delay Margin Estimation for Adaptive Control and Optimal Control Modification
NASA Technical Reports Server (NTRS)
Nguyen, Nhan T.
2011-01-01
This paper presents methods for estimating time delay margin for adaptive control of input delay systems with almost linear structured uncertainty. The bounded linear stability analysis method seeks to represent an adaptive law by a locally bounded linear approximation within a small time window. The time delay margin of this input delay system represents a local stability measure and is computed analytically by three methods: Pade approximation, Lyapunov-Krasovskii method, and the matrix measure method. These methods are applied to the standard model-reference adaptive control, s-modification adaptive law, and optimal control modification adaptive law. The windowing analysis results in non-unique estimates of the time delay margin since it is dependent on the length of a time window and parameters which vary from one time window to the next. The optimal control modification adaptive law overcomes this limitation in that, as the adaptive gain tends to infinity and if the matched uncertainty is linear, then the closed-loop input delay system tends to a LTI system. A lower bound of the time delay margin of this system can then be estimated uniquely without the need for the windowing analysis. Simulation results demonstrates the feasibility of the bounded linear stability method for time delay margin estimation.
Impact of time delays on oscillatory dynamics of interlinked positive and negative feedback loops
NASA Astrophysics Data System (ADS)
Huang, Bo; Tian, Xinyu; Liu, Feng; Wang, Wei
2016-11-01
Interlinking a positive feedback loop (PFL) with a negative feedback loop (NFL) constitutes a typical motif in genetic networks, performing various functions in cell signaling. How time delay in feedback regulation affects the dynamics of such systems still remains unclear. Here, we investigate three systems of interlinked PFL and NFL with time delays: a synthetic genetic oscillator, a three-node circuit, and a simplified single-node model. The stability of steady states and the routes to oscillation in the single-node model are analyzed in detail. The amplitude and period of oscillations vary with a pointwise periodicity over a range of time delay. Larger-amplitude oscillations can be induced when the PFL has an appropriately long delay, in comparison with the PFL with no delay or short delay; this conclusion holds true for all the three systems. We unravel the underlying mechanism for the above effects via analytical derivation under a limiting condition. We also develop a stochastic algorithm for simulating a single reaction with two delays and show that robust oscillations can be maintained by the PFL with a properly long delay in the single-node system. This work presents an effective method for constructing robust large-amplitude oscillators and interprets why similar circuit architectures are engaged in timekeeping systems such as circadian clocks.
Complex dynamics in the Leslie-Gower type of the food chain system with multiple delays
NASA Astrophysics Data System (ADS)
Guo, Lei; Song, Zi-Gen; Xu, Jian
2014-08-01
In this paper, we present a Leslie-Gower type of food chain system composed of three species, which are resource, consumer, and predator, respectively. The digestion time delays corresponding to consumer-eat-resource and predator-eat-consumer are introduced for more realistic consideration. It is called the resource digestion delay (RDD) and consumer digestion delay (CDD) for simplicity. Analyzing the corresponding characteristic equation, the stabilities of the boundary and interior equilibrium points are studied. The food chain system exhibits the species coexistence for the small values of digestion delays. Large RDD/CDD may destabilize the species coexistence and induce the system dynamic into recurrent bloom or system collapse. Further, the present of multiple delays can control species population into the stable coexistence. To investigate the effect of time delays on the recurrent bloom of species population, the Hopf bifurcation and periodic solution are investigated in detail in terms of the central manifold reduction and normal form method. Finally, numerical simulations are performed to display some complex dynamics, which include multiple periodic solution and chaos motion for the different values of system parameters. The system dynamic behavior evolves into the chaos motion by employing the period-doubling bifurcation.
Consistency properties of chaotic systems driven by time-delayed feedback
NASA Astrophysics Data System (ADS)
Jüngling, T.; Soriano, M. C.; Oliver, N.; Porte, X.; Fischer, I.
2018-04-01
Consistency refers to the property of an externally driven dynamical system to respond in similar ways to similar inputs. In a delay system, the delayed feedback can be considered as an external drive to the undelayed subsystem. We analyze the degree of consistency in a generic chaotic system with delayed feedback by means of the auxiliary system approach. In this scheme an identical copy of the nonlinear node is driven by exactly the same signal as the original, allowing us to verify complete consistency via complete synchronization. In the past, the phenomenon of synchronization in delay-coupled chaotic systems has been widely studied using correlation functions. Here, we analytically derive relationships between characteristic signatures of the correlation functions in such systems and unequivocally relate them to the degree of consistency. The analytical framework is illustrated and supported by numerical calculations of the logistic map with delayed feedback for different replica configurations. We further apply the formalism to time series from an experiment based on a semiconductor laser with a double fiber-optical feedback loop. The experiment constitutes a high-quality replica scheme for studying consistency of the delay-driven laser and confirms the general theoretical results.
Compact programmable photonic variable delay devices
NASA Technical Reports Server (NTRS)
Yao, X. Steve (Inventor)
1999-01-01
Optical variable delay devices for providing variable true time delay to multiple optical beams simultaneously. A ladder-structured variable delay device comprises multiple basic building blocks stacked on top of each other resembling a ladder. Each basic building block has two polarization beamsplitters and a polarization rotator array arranged to form a trihedron; Controlling an array element of the polarization rotator array causes a beam passing through the array element either going up to a basic building block above it or reflect back towards a block below it. The beams going higher on the ladder experience longer optical path delay. An index-switched optical variable delay device comprises of many birefringent crystal segments connected with one another, with a polarization rotator array sandwiched between any two adjacent crystal segments. An array element in the polarization rotator array controls the polarization state of a beam passing through the element, causing the beam experience different refractive indices or path delays in the following crystal segment. By independently control each element in each polarization rotator array, variable optical path delays of each beam can be achieved. Finally, an index-switched variable delay device and a ladder-structured variable device are cascaded to form a new device which combines the advantages of the two individual devices. This programmable optic device has the properties of high packing density, low loss, easy fabrication, and virtually infinite bandwidth. The device is inherently two dimensional and has a packing density exceeding 25 lines/cm.sup.2. The delay resolution of the device is on the order of a femtosecond (one micron in space) and the total delay exceeds 10 nanosecond. In addition, the delay is reversible so that the same delay device can be used for both antenna transmitting and receiving.
Chang, Ching Thon; Esterman, Adrain
2007-01-01
Delayed diagnosis of tuberculosis (TB) can lead to an increased period of infectivity in the community, a delay in treatment and a severe form of the disease. The objective of this study was to determine the length of delay, and factors linking the delay from the onset of symptoms of pulmonary tuberculosis (PTB) until the commencement of treatment in Sarawak, Malaysia. An institution based cross-sectional study was conducted in 10 TB clinics in randomly selected divisions in Sarawak from June 2003 to May 2004. Delay was analyzed from two perspectives: (1) period between the onset of TB symptoms to any first medical consultation (patients' delay); and (2) period between the first medical consultation to the diagnosis of TB (diagnosis delay). Patients were interviewed on diagnosis or within the admission period using a semi-structured questionnaire. A total of 316 new smear-positive PTB patients participated in the study. The median patient interval was 30 days. Gender was found to be significantly associated with patient delay. The median diagnosis interval was 22 days. Respondents' incomes, health-care professional first consulted and actions taken by the health-care providers during the first consultation were significantly associated with diagnosis delay. The medium treatment interval was 0 days. Both patients and health providers played a role in delaying TB diagnosis. Females appeared to have longer delay. Respondents living above the poverty line had diagnosis delay as they made more visits to GPs or different government clinics without proper investigations for TB. A mechanism is needed to increase all health-care providers' suspicion of TB so that proper investigations can be done during first consultation.
Photonic variable delay devices based on optical birefringence
NASA Technical Reports Server (NTRS)
Yao, X. Steve (Inventor)
2005-01-01
Optical variable delay devices for providing variable true time delay to multiple optical beams simultaneously. A ladder-structured variable delay device comprises multiple basic building blocks stacked on top of each other resembling a ladder. Each basic building block has two polarization beamsplitters and a polarization rotator array arranged to form a trihedron; Controlling an array element of the polarization rotator array causes a beam passing through the array element either going up to a basic building block above it or reflect back towards a block below it. The beams going higher on the ladder experience longer optical path delay. An index-switched optical variable delay device comprises of many birefringent crystal segments connected with one another, with a polarization rotator array sandwiched between any two adjacent crystal segments. An array element in the polarization rotator array controls the polarization state of a beam passing through the element, causing the beam experience different refractive indices or path delays in the following crystal segment. By independently control each element in each polarization rotator array, variable optical path delays of each beam can be achieved. Finally, an index-switched variable delay device and a ladder-structured variable device are cascaded to form a new device which combines the advantages of the two individual devices. This programmable optic device has the properties of high packing density, low loss, easy fabrication, and virtually infinite bandwidth. The device is inherently two dimensional and has a packing density exceeding 25 lines/cm2. The delay resolution of the device is on the order of a femtosecond (one micron in space) and the total delay exceeds 10 nanosecond. In addition, the delay is reversible so that the same delay device can be used for both antenna transmitting and receiving.
Physics Goals for the Planned Next Linear Collider Engineering Test Facility
DOE Office of Scientific and Technical Information (OSTI.GOV)
Raubenheimer, Tor O
2001-10-02
The Next Linear Collider (NLC) Collaboration is planning to construct an Engineering Test Facility (ETF) at Fermilab. As presently envisioned, the ETF would comprise a fundamental unit of the NLC main linac to include X-band klystrons and modulators, a delay-line power-distribution system (DLDS), and NLC accelerating structures that serve as loads. The principal purpose of the ETF is to validate stable operation of the power-distribution system, first without beam, then with a beam having the NLC pulse structure. This paper concerns the possibility of configuring and using the ETF to accelerate beam with an NLC pulse structure, as well asmore » of doing experiments to measure beam-induced wakefields in the rf structures and their influence back on the beam.« less
Physics goals for the planned next linear collider engineering test facility
DOE Office of Scientific and Technical Information (OSTI.GOV)
Courtlandt L Bohn et al.
2001-06-26
The Next Linear Collider (NLC) Collaboration is planning to construct an Engineering Test Facility (ETF) at Fermilab. As presently envisioned, the ETF would comprise a fundamental unit of the NLC main linac to include X-band klystrons and modulators, a delay-line power-distribution system (DLDS), and NLC accelerating structures that serve as loads. The principal purpose of the ETF is to validate stable operation of the power-distribution system, first without beam, then with a beam having the NLC pulse structure. This paper concerns the possibility of configuring and using the ETF to accelerate beam with an NLC pulse structure, as well asmore » of doing experiments to measure beam-induced wakefields in the rf structures and their influence back on the beam.« less
Physics goals for the planned next linear collider engineering test facility.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Bohn, C.; Michelotti, L.; Ostiguy, J.-F.
2001-07-17
The Next Linear Collider (NLC) Collaboration is planning to construct an Engineering Test Facility (ETF) at Fermilab. As presently envisioned, the ETF would comprise a fundamental unit of the NLC main linac to include X-band klystrons and modulators, a delay-line power-distribution system (DLDS), and NLC accelerating structures that serve as loads. The principal purpose of the ETF is to validate stable operation of the power-distribution system, first without beam, then with a beam having the NLC pulse structure. This paper concerns the possibility of configuring and using the ETF to accelerate beam with an NLC pulse structure, as well asmore » of doing experiments to measure beam-induced wakefields in the rf structures and their influence back on the beam.« less