Computational assessment of deep-seated tumor treatment capability of the 9Be(d,n)10B reaction for accelerator-based boron neutron capture therapy (AB-BNCT).

PubMed

Capoulat, M E; Minsky, D M; Kreiner, A J

2014-03-01

The 9Be(d,n)10B reaction was studied as an epithermal neutron source for brain tumor treatment through Boron Neutron Capture Therapy (BNCT). In BNCT, neutrons are classified according to their energies as thermal (<0.5 eV), epithermal (from 0.5 eV to 10 keV) or fast (>10 keV). For deep-seated tumors epithermal neutrons are needed. Since a fraction of the neutrons produced by this reaction are quite fast (up to 5-6 MeV, even for low-bombarding energies), an efficient beam shaping design is required. This task was carried out (1) by selecting the combinations of bombarding energy and target thickness that minimize the highest-energy neutron production; and (2) by the appropriate choice of the Beam Shaping Assembly (BSA) geometry, for each of the combinations found in (1). The BSA geometry was determined as the configuration that maximized the dose deliverable to the tumor in a 1 h treatment, within the constraints imposed by the healthy tissue dose adopted tolerance. Doses were calculated through the MCNP code. The highest dose deliverable to the tumor was found for an 8 μm target and a deuteron beam of 1.45 MeV. Tumor weighted doses ≥40 Gy can be delivered up to about 5 cm in depth, with a maximum value of 51 Gy at a depth of about 2 cm. This dose performance can be improved by relaxing the treatment time constraint and splitting the treatment into two 1-h sessions. These good treatment capabilities strengthen the prospects for a potential use of this reaction in BNCT. Copyright © 2013 Associazione Italiana di Fisica Medica. Published by Elsevier Ltd. All rights reserved.

Urban morphological determinants of temperature regulating ecosystem services in African cities: the case of Dar es Salaam, Tanzania

NASA Astrophysics Data System (ADS)

Cavan, Gina; Lindley, Sarah; Kibassa, Deusdedit; Shemdoe, Riziki; Capuano, Paolo; De Paola, Francesco; Renner, Florian; Pauleit, Stephan

2013-04-01

Urban green structure provides important regulating ecosystem services, such as temperature and flood regulation, and thus, has the potential to increase the resilience of African cities to climate change. Green structures within urban areas are not only limited to discrete units associated with recreational parks, agricultural areas and open spaces: they also exist within zones which have other primary functions, such as church yards, along transport routes, and within residential areas. Differing characteristics of urban areas can be conceptualised and subsequently mapped through the idea of urban morphology types. Urban morphology types are classifications which combine facets of urban form and function. When mapped, UMT units provide biophysically relevant meso-scale geographical zones which can be used as the basis for understanding climate-related impacts and adaptations. For example, they support the assessment of urban temperature patterns and the temperature regulating services provided by urban green structures. There are some examples of the use of UMTs for assessing regulating ecosystem services in European cities but little similar knowledge is available in an African context. This paper outlines the concept of urban morphology types (UMTs) and how they were applied to African case study cities (Cavan et al., 2012). It then presents the methods used to understand temperature regulating ecosystem services across an example African case study city, including (i) a GIS-based assessment of urban green structures, and (ii) applying an energy balance model to estimate current and future surface temperatures under climate change projections. The assessment is carried out for Dar es Salaam, Tanzania. Existing evidence suggests increases in both mean and extreme temperatures in the city. Historical analysis of the number of hot days per year suggests a rise from a maximum of 47 days per year in the period 1961-87 to 72 days per year in 2003-2011 (Giugni et al., 2012). Mean temperatures in the climate zone are estimated to increase by at least 1°C between 1971-2000 and 2021-2050(CSIR, 2012). Dar es Salaam is represented using around 1700 UMT units mapped across 43 UMT categories for the year 2008. Modelled surface temperature profiles for the city are presented, including an assessment of the potential impact of changing green structure cover within selected UMT categories. Provisional recommendations are made concerning the potential contribution of green structures as a climate adaptation response to the increasing temperatures in Dar es Salaam, which could be relevant for other African cities in similar climate zones. References Cavan, G., Lindley, S., Yeshitela, K., Nebebe, A., Woldegerima, T., Shemdoe, R., Kibassa, D., Pauleit, S., Renner, R., Printz, A., Buchta, K., Coly, A., Sall, F., Ndour, N. M., Ouédraogo, Y., Samari, B. S., Sankara, B. T., Feumba, R. A., Ngapgue, J. N., Ngoumo, M. T., Tsalefac, M., Tonye, E. (2012) CLUVA deliverable D2.7 Green infrastructure maps for selected case studies and a report with an urban green infrastructure mapping methodology adapted to African cities. http://www.cluva.eu/deliverables/CLUVA_D2.7.pdf. Accessed 18/12/12. CSIR (2012) CLUVA deliverable D1.5 Regional climate change simulations available for the selected areas http://www.cluva.eu/deliverables/CLUVA_D1.5.pdf. Accessed 8/1/13. Giugni, M., Adamo, P., Capuano, P., De Paola, F., Di Ruocco, A., Giordano, S., Iavazzo, P., Sellerino, M., Terracciano, S., Topa, M. E. (2012) CLUVA deliverable D.1.2 Hazard scenarios for test cities using available data. http://www.cluva.eu/deliverables/CLUVA_D1.2.pdf. Accessed 8/1/13

The National Shipbuilding Research Program. Application of Industrial Engineering Techniques to Reduce Workers’ Compensation and Environmental Costs - Deliverable D

DTIC Science & Technology

1999-10-01

Electrostatic guns provide opportunities for exterior application of topcoats such as urethanes, acrylics , alkyds and epoxies. Most shipbuilding...A hybrid of airless spray and conventional air-atomized spray, this kind of gun uses fluid pressures higher than those used in conventional air...voltage) by simply flipping a switch. All essential controls are located right at the back of the gun. Other electrostatic systems require constant

US Army Research Laboratory Materials Center of Excellence. Dynamic Behavior of Noncrystalline and Nanocrystalline Metallic Systems: July 2011-June 2012 Annual Report

DTIC Science & Technology

2015-03-01

Presentations 18 6. High-Rate Loading of Piezoelectric Ceramics 19 6.1 Objective 19 6.2 Quarterly Deliverables 19 6.3 Research Summary 19 6.4...the mechanical properties and to control the failure, with the emphasis on those properties and processes that are unique to BCC materials . The...application to molybdenum. 19 6. High-Rate Loading of Piezoelectric Ceramics Core Faculty: KT Ramesh ARL Collaborators: George Gazonas, Jim McCauley

Modified Sierpenski Antenna With Metamaterial For Wireless Applications

NASA Astrophysics Data System (ADS)

Aggarwal, Ishita; Pandey, Sujata

2017-08-01

This paper presents a multiband antenna based on modified sierpenski fractal structure along with metamaterials for wireless applications. Multi bands are obtained at 2.1 GHz, 5.73 GHz, 7.6 GHz and 8.4 GHz with return losses -21.49 dB,-36.36 dB,-45dB, and -23.46 dBrespectively. The dimension of the substrate used for this antenna is 52 x 60 x 1.6 mm3 and dielectric constant is 4.4 with tanδ of 0.002. The peak gain of 6.6 dB, return loss of -45 dB and VSWR of 1 are obtained at 7.6 GHz. Metamaterial unit cells are loaded on ground to improve the antenna parameters. This is a simple and compact design and has multiband features suitable for WIMAX, WLAN, C-band and X-band applications. This design is simulated by using HFSS 14.

US-VISIT Identity Matching Algorithm Evaluation Program: ADIS Algorithm Evaluation Project Plan Update

DOE Office of Scientific and Technical Information (OSTI.GOV)

Grant, C W; Lenderman, J S; Gansemer, J D

This document is an update to the 'ADIS Algorithm Evaluation Project Plan' specified in the Statement of Work for the US-VISIT Identity Matching Algorithm Evaluation Program, as deliverable II.D.1. The original plan was delivered in August 2010. This document modifies the plan to reflect modified deliverables reflecting delays in obtaining a database refresh. This document describes the revised schedule of the program deliverables. The detailed description of the processes used, the statistical analysis processes and the results of the statistical analysis will be described fully in the program deliverables. The US-VISIT Identity Matching Algorithm Evaluation Program is work performed bymore » Lawrence Livermore National Laboratory (LLNL) under IAA HSHQVT-07-X-00002 P00004 from the Department of Homeland Security (DHS).« less

Interim report deliverable 1.1 : RADAR sensors for transportation applications of the restricted use technology study

DOT National Transportation Integrated Search

2005-09-30

Under Deliverable 1.1 of the Work Plan governing the Altarum Restricted Use Technology Study, the Altarum project team is required to produce an unclassified summary and comprehensive written report of RADAR systems that can potentially address trans...

Interim report deliverable 2.1 : electro-optical sensors for transportation applications of the restricted use technology study

DOT National Transportation Integrated Search

2005-09-30

Under Deliverable 2.1 of the Work Plan governing the Altarum Restricted Use Technology Study, the Altarum project team is required to produce an unclassified summary and comprehensive written report of Electro-Optical (EO) systems that can potentiall...

Improvements Needed in U.S. Special Operations Command Global Battlestaff and Program Support Contract Oversight

DTIC Science & Technology

2013-04-26

and 6-8 books annually. Some deliverables are due “as required.” This is because the mission of the IATF is dependent upon real-world events and...six lines of investigation (4.1.18). Some deliverables do not have specific due dates or schedules because the mission of the IATF is dependent upon...34 This is because the mission of the IATF is dependent upon real-world events and deliverables are linked to dynamic findings from the SOCOM GSC

Finite Element Development and Specifications of a Patched, Recessed Nomex Core Honeycomb Panel for Increased Sound Transmission Loss

NASA Technical Reports Server (NTRS)

Grosveld, Ferdinand W.

2007-01-01

This informal report summarizes the development and the design specifications of a recessed nomex core honeycomb panel in fulfillment of the deliverable in Task Order 13RBE, Revision 10, Subtask 17. The honeycomb panel, with 0.020-inch thick aluminum face sheets, has 0.016-inch thick aluminum patches applied to twenty-five, 6 by 6 inch, quarter inch thick recessed cores. A 10 dB higher transmission loss over the frequency range 250 - 1000 Hz was predicted by a MSC/NASTRAN finite element model when compared with the transmission loss of the base nomex core honeycomb panel. The static displacement, due to a unit force applied at either the core or recessed core area, was of the same order of magnitude as the static displacement of the base honeycomb panel when exposed to the same unit force. The mass of the new honeycomb design is 5.1% more than the base honeycomb panel. A physical model was constructed and is being tested.

29 CFR 2530.200b-6 - Maritime industry.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 29 Labor 9 2010-07-01 2010-07-01 false Maritime industry. 2530.200b-6 Section 2530.200b-6 Labor... Provisions § 2530.200b-6 Maritime industry. (a) General. Sections 202(a)(3)(D), 203(b)(2)(D) and 204(b)(3)(E... provisions applicable to the maritime industry. In general, those provisions permit statutory standards...

29 CFR 2530.200b-6 - Maritime industry.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 29 Labor 9 2014-07-01 2014-07-01 false Maritime industry. 2530.200b-6 Section 2530.200b-6 Labor... Provisions § 2530.200b-6 Maritime industry. (a) General. Sections 202(a)(3)(D), 203(b)(2)(D) and 204(b)(3)(E... provisions applicable to the maritime industry. In general, those provisions permit statutory standards...

29 CFR 2530.200b-6 - Maritime industry.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 29 Labor 9 2011-07-01 2011-07-01 false Maritime industry. 2530.200b-6 Section 2530.200b-6 Labor... Provisions § 2530.200b-6 Maritime industry. (a) General. Sections 202(a)(3)(D), 203(b)(2)(D) and 204(b)(3)(E... provisions applicable to the maritime industry. In general, those provisions permit statutory standards...

29 CFR 2530.200b-6 - Maritime industry.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 29 Labor 9 2013-07-01 2013-07-01 false Maritime industry. 2530.200b-6 Section 2530.200b-6 Labor... Provisions § 2530.200b-6 Maritime industry. (a) General. Sections 202(a)(3)(D), 203(b)(2)(D) and 204(b)(3)(E... provisions applicable to the maritime industry. In general, those provisions permit statutory standards...

29 CFR 2530.200b-6 - Maritime industry.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 29 Labor 9 2012-07-01 2012-07-01 false Maritime industry. 2530.200b-6 Section 2530.200b-6 Labor... Provisions § 2530.200b-6 Maritime industry. (a) General. Sections 202(a)(3)(D), 203(b)(2)(D) and 204(b)(3)(E... provisions applicable to the maritime industry. In general, those provisions permit statutory standards...

The National Shipbuilding Research Program. Application of Industrial Engineering Techniques to Reduce Worker’s Compensation and Environmental Costs - Deliverable A

DTIC Science & Technology

1999-10-01

N8-96-3 Application of Industrial Engineering Techniques to Reduce Workers ’ Compensation and Environmental Costs - Deliverable A U.S. DEPARTMENT OF...disclosed in the report. As used in the above, “Persons acting on behalf of the United States Navy” includes any employee , contractor, or subcontractor to...the contractor of the United States Navy to the extent that such employee , contractor, or subcontractor to the contractor prepares, handles, or

Earth Observing System (EOS)/Advanced Microwave Sounding Unit A (AMSU-A) configuration management plan

NASA Technical Reports Server (NTRS)

Cavanaugh, J.

1994-01-01

This plan describes methods and procedures Aerojet will follow in the implementation of configuration control for each established baseline. The plan is written in response to the GSFC EOS CM Plan 420-02-02, dated January 1990, and also meets he requirements specified in DOD-STD-480, DOD-D 1000B, MIL-STD-483A, and MIL-STD-490B. The plan establishes the configuration management process to be used for the deliverable hardware, software, and firmware of the EOS/AMSU-A during development, design, fabrication, test, and delivery. This revision includes minor updates to reflect Aerojet's CM policies.

Anisotropic Grid Generation

DTIC Science & Technology

2016-03-24

AFRL-AFOSR-VA-TR-2016-0129 ANISOTROPIC GRID GENERATION | Deliverables Daniel Sievenpiper UNIVERSITY OF CALIFORNIA SAN DIEGO Final Report 03/24/2016...ORGANIZATION. 1. REPORT DATE (DD-MM-YYYY) 12-03-2016 2 . REPORT TYPE Final report 3. DATES COVERED (From - To) 15-12-2012 - 14-12-2015 4. TITLE AND...SUBTITLE Anisotropic Grid Generation 5a. CONTRACT NUMBER 5b. GRANT NUMBER FA9550-13-1-0014 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Daniel

Synthetic Report of Research and Development of Professional Knowledge Practices

ERIC Educational Resources Information Center

Toiviainen, Hanna; Hoynalanmaa, Mikko; Lallimo, Jiri; Moen, Anne; Smordal, Ole; Morch, Anders; Toikka, Seppo

2006-01-01

This deliverable has been produced in the context of the Knowledge-Practice Laboratory (KP-Lab) project, which is aimed at facilitating innovative practices of working with knowledge in higher education, teacher training, and professional networks. This deliverable is a synopsis of the first experiences encountered during the first 6 months of the…

Competitiveness Improvement Project Informational Workshop

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sinclair, Karin C; Preus, Robert W; Dana, Scott

This presentation was given at the Competitiveness Improvement Project (CIP) Informational Workshop on December 6, 2017. Topics covered during the workshop include an overview of the CIP, past projects, scoring criteria, technical support opportunities, certification body requirements, standards applicable to distributed wind generators, information on the National Electric Code, certification testing requirements, test site requirements, National Environmental Policy Act, design review, levelized cost of energy, procurement/contracting, project management/deliverables, and outreach materials.

Selective Window Application of Gentamicin+ Dexamethasone in Meniere's Disease.

PubMed

Ardıç, Fazıl Necdet; Tümkaya, Funda; Aykal, Kamil; Çabuk, Burçin

2017-08-01

The purpose of the study is to prevent hearing loss when using intratympanic (IT) gentamicin for intractable Meniere's disease. It is a retrospective case review study. Twenty five patients who had definite Meniere's disease and had either selective window application or weekly IT gentamicin were included into the study. First group (selective) had dexamethasone on the round window and gentamicin on oval window during exploratory tympanotomy procedure. The second group had IT gentamicin at weekly intervals. The degree of caloric weakness (CW), average hearing level in low pitch (HLP) (250, 500, 1000, 2000 Hz) and high pitch (HHP) (4000, 6000, 8000 Hz) were compared before and after treatment. The need for further treatment was noted. In the first group, the average HLP was increased from 51.6±7dB to 52.2±5.6 dB. The average HHP was increased 41.96±20.2 dB to 47.2±18.3 dB after treatment. The CW changed from 37.6±23.9 % to 54.6±30.6 %. In the second group, the average HLP was increased from 56.3±10.5 dB to 61.65±18.3 dB. The average HHP was increased 59.05±17.4 dB to 69.4±21.98 dB after treatment. The CW changed from 45.8±22.3% to 71.53±29.63 %. Both methods had statisticaly significant increase in caloric weakness. But only IT gentamicin led a significant hearing loss in HHP. The use of dexamethasone and gentamycin via different windows in the middle ear is safe and effective method for Meniere's disease in the short term. Application of dexamethasone protects not only the hearing cells but vestibular cells also.

Application of fuzzy logic-neural network based reinforcement learning to proximity and docking operations: Special approach/docking testcase results

NASA Technical Reports Server (NTRS)

Jani, Yashvant

1993-01-01

As part of the RICIS project, the reinforcement learning techniques developed at Ames Research Center are being applied to proximity and docking operations using the Shuttle and Solar Maximum Mission (SMM) satellite simulation. In utilizing these fuzzy learning techniques, we use the Approximate Reasoning based Intelligent Control (ARIC) architecture, and so we use these two terms interchangeably to imply the same. This activity is carried out in the Software Technology Laboratory utilizing the Orbital Operations Simulator (OOS) and programming/testing support from other contractor personnel. This report is the final deliverable D4 in our milestones and project activity. It provides the test results for the special testcase of approach/docking scenario for the shuttle and SMM satellite. Based on our experience and analysis with the attitude and translational controllers, we have modified the basic configuration of the reinforcement learning algorithm in ARIC. The shuttle translational controller and its implementation in ARIC is described in our deliverable D3. In order to simulate the final approach and docking operations, we have set-up this special testcase as described in section 2. The ARIC performance results for these operations are discussed in section 3 and conclusions are provided in section 4 along with the summary for the project.

Artificial intelligence applications in logistics information systems : final report

DOT National Transportation Integrated Search

1990-04-01

This report is the principal deliverable from the LIMSS-AI project. It summarizes the results of a survey of existing applications and discusses the feasibility and benefits of specific candidate logistics applications.

Final Report Extreme Computing and U.S. Competitiveness DOE Award. DE-FG02-11ER26087/DE-SC0008764

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mustain, Christopher J.

The Council has acted on each of the grant deliverables during the funding period. The deliverables are: (1) convening the Council’s High Performance Computing Advisory Committee (HPCAC) on a bi-annual basis; (2) broadening public awareness of high performance computing (HPC) and exascale developments; (3) assessing the industrial applications of extreme computing; and (4) establishing a policy and business case for an exascale economy.

Extended Range Underwater Loudhailer for Port Security Applications

DTIC Science & Technology

2006-06-01

and Subtitle Extended Range Underwater Loudhailer for Port Security Applications 6. Performing Organization Code Project No. 5903 7. Author( s ...used in the audio market . The name ‘RCA’ derives from the Radio Corporation of America, which introduced the design, by the early 1940s, to allow...Test June 2005 Test Range (yds) S pe ct ru m B an d Le ve l ( dB re 1 µ P a) S pe ct ru m B an d Le ve l ( dB re 1 µ P a) Figure 9

40 CFR 132.6 - Application of part 132 requirements in Great Lakes States and Tribes.

Code of Federal Regulations, 2011 CFR

2011-07-01

... the State of Indiana. (b) Effective September 5, 2000, the requirements of Procedure 3 in Appendix F... in the States of Indiana, Michigan and Ohio. (d) Effective November 6, 2000, § 132.4(d)(2) shall... a total concentration. (b) Chemical mA bA Conversion factor (CF) Cadmium a,b 1.128 −3.6867 0.85...

40 CFR 132.6 - Application of part 132 requirements in Great Lakes States and Tribes.

Code of Federal Regulations, 2010 CFR

2010-07-01

... the State of Indiana. (b) Effective September 5, 2000, the requirements of Procedure 3 in Appendix F... in the States of Indiana, Michigan and Ohio. (d) Effective November 6, 2000, § 132.4(d)(2) shall... a total concentration. (b) Chemical mA bA Conversion factor (CF) Cadmium a,b 1.128 −3.6867 0.85...

Texture analysis on the fluence map to evaluate the degree of modulation for volumetric modulated arc therapy.

PubMed

Park, So-Yeon; Kim, Il Han; Ye, Sung-Joon; Carlson, Joel; Park, Jong Min

2014-11-01

Texture analysis on fluence maps was performed to evaluate the degree of modulation for volumetric modulated arc therapy (VMAT) plans. A total of six textural features including angular second moment, inverse difference moment, contrast, variance, correlation, and entropy were calculated for fluence maps generated from 20 prostate and 20 head and neck VMAT plans. For each of the textural features, particular displacement distances (d) of 1, 5, and 10 were adopted. To investigate the deliverability of each VMAT plan, gamma passing rates of pretreatment quality assurance, and differences in modulating parameters such as multileaf collimator (MLC) positions, gantry angles, and monitor units at each control point between VMAT plans and dynamic log files registered by the Linac control system during delivery were acquired. Furthermore, differences between the original VMAT plan and the plan reconstructed from the dynamic log files were also investigated. To test the performance of the textural features as indicators for the modulation degree of VMAT plans, Spearman's rank correlation coefficients (rs) with the plan deliverability were calculated. For comparison purposes, conventional modulation indices for VMAT including the modulation complexity score for VMAT, leaf travel modulation complexity score, and modulation index supporting station parameter optimized radiation therapy (MISPORT) were calculated, and their correlations were analyzed in the same way. There was no particular textural feature which always showed superior correlations with every type of plan deliverability. Considering the results comprehensively, contrast (d = 1) and variance (d = 1) generally showed considerable correlations with every type of plan deliverability. These textural features always showed higher correlations to the plan deliverability than did the conventional modulation indices, except in the case of modulating parameter differences. The rs values of contrast to the global gamma passing rates with criteria of 2%/2 mm, 2%/1 mm, and 1%/2 mm were 0.536, 0.473, and 0.718, respectively. The respective values for variance were 0.551, 0.481, and 0.688. In the case of local gamma passing rates, the rs values of contrast were 0.547, 0.578, and 0.620, respectively, and those of variance were 0.519, 0.527, and 0.569. All of the rs values in those cases were statistically significant (p < 0.003). In the cases of global and local gamma passing rates, MISPORT showed the highest correlations among the conventional modulation indices. For global passing rates, rs values of MISPORT were -0.420, -0.330, and -0.632, respectively, and those for local passing rates were -0.455, -0.490 and -0.502. The values of rs of contrast, variance, and MISPORT with the MLC errors were -0.863, -0.828, and 0.795, respectively, all with statistical significances (p < 0.001). The correlations with statistical significances between variance and dose-volumetric differences were observed more frequently than the others. The contrast (d = 1) and variance (d = 1) calculated from fluence maps of VMAT plans showed considerable correlations with the plan deliverability, indicating their potential use as indicators for assessing the degree of modulation of VMAT plans. Both contrast and variance consistently showed better performance than the conventional modulation indices for VMAT.

Connected Vehicle Pilot Deployment Program phase 1 : application deployment plan : New York City : final application deployment plan.

DOT National Transportation Integrated Search

2016-08-04

This document is the Task 7 Application Deployment Plan deliverable for the New York City Connected Vehicle Pilot Deployment. It describes the process that the deployment team will follow to acquire and test the connected vehicle safety applications....

Computational discovery of metal-organic frameworks with high gas deliverable capacity

NASA Astrophysics Data System (ADS)

Bao, Yi

Metal-organic frameworks (MOFs) are a rapidly emerging class of nanoporous materials with largely tunable chemistry and diverse applications in gas storage, gas purification, catalysis, sensing and drug delivery. Efforts have been made to develop new MOFs with desirable properties both experimentally and computationally for decades. To guide experimental synthesis, we here develop a computational methodology to explore MOFs with high gas deliverable capacity. This de novo design procedure applies known chemical reactions, considers synthesizability and geometric requirements of organic linkers, and efficiently evolves a population of MOFs to optimize a desirable property. We identify 48 MOFs with higher methane deliverable capacity at 65-5.8 bar condition than the MOF-5 reference in nine networks. In a more comprehensive work, we predict two sets of MOFs with high methane deliverable capacity at a 65-5.8 bar loading-delivery condition or a 35-5.8 bar loading-delivery condition. We also optimize a set of MOFs with high methane accessible internal surface area to investigate the relationship between deliverable capacities and internal surface area. This methodology can be extended to MOFs with multiple types of linkers and multiple SBUs. Flexibile MOFs may allow for sophisticated heat management strategies and also provide higher gas deliverable capacity than rigid frameworks. We investigate flexible MOFs, such as MIL-53 families, and Fe(bdp) and Co(bdp) analogs, to understand the structural phase transition of frameworks and the resulting influence on heat of adsorption. Challenges of simulating a system with a flexible host structure and incoming guest molecules are discussed. Preliminary results from isotherm simulation using the hybrid MC/MD simulation scheme on MIL-53(Cr) are presented. Suggestions for proceeding to understand the free energy profile of flexible MOFs are provided.

40 CFR 132.6 - Application of part 132 requirements in Great Lakes States and Tribes.

Code of Federal Regulations, 2012 CFR

2012-07-01

... the State of Indiana. (b) Effective September 5, 2000, the requirements of Procedure 3 in appendix F... in the States of Indiana, Michigan and Ohio. (d) Effective November 6, 2000, § 132.4(d)(2) shall...) Chemical mA bA Conversion factor (CF) Cadmium a,b 1.128 −3.6867 0.85 Chromium (III) a,b 0.819 +3.7256 0.316...

40 CFR 132.6 - Application of part 132 requirements in Great Lakes States and Tribes.

Code of Federal Regulations, 2014 CFR

2014-07-01

... the State of Indiana. (b) Effective September 5, 2000, the requirements of Procedure 3 in appendix F... in the States of Indiana, Michigan and Ohio. (d) Effective November 6, 2000, § 132.4(d)(2) shall...) Chemical mA bA Conversion factor (CF) Cadmium a,b 1.128 −3.6867 0.85 Chromium (III) a,b 0.819 +3.7256 0.316...

40 CFR 132.6 - Application of part 132 requirements in Great Lakes States and Tribes.

Code of Federal Regulations, 2013 CFR

2013-07-01

... the State of Indiana. (b) Effective September 5, 2000, the requirements of Procedure 3 in appendix F... in the States of Indiana, Michigan and Ohio. (d) Effective November 6, 2000, § 132.4(d)(2) shall...) Chemical mA bA Conversion factor (CF) Cadmium a,b 1.128 −3.6867 0.85 Chromium (III) a,b 0.819 +3.7256 0.316...

Advantages and limitations of navigation-based multicriteria optimization (MCO) for localized prostate cancer IMRT planning

DOE Office of Scientific and Technical Information (OSTI.GOV)

McGarry, Conor K., E-mail: conor.mcgarry@belfasttrust.hscni.net; Bokrantz, Rasmus; RaySearch Laboratories, Stockholm

2014-10-01

Efficacy of inverse planning is becoming increasingly important for advanced radiotherapy techniques. This study’s aims were to validate multicriteria optimization (MCO) in RayStation (v2.4, RaySearch Laboratories, Sweden) against standard intensity-modulated radiation therapy (IMRT) optimization in Oncentra (v4.1, Nucletron BV, the Netherlands) and characterize dose differences due to conversion of navigated MCO plans into deliverable multileaf collimator apertures. Step-and-shoot IMRT plans were created for 10 patients with localized prostate cancer using both standard optimization and MCO. Acceptable standard IMRT plans with minimal average rectal dose were chosen for comparison with deliverable MCO plans. The trade-off was, for the MCO plans, managedmore » through a user interface that permits continuous navigation between fluence-based plans. Navigated MCO plans were made deliverable at incremental steps along a trajectory between maximal target homogeneity and maximal rectal sparing. Dosimetric differences between navigated and deliverable MCO plans were also quantified. MCO plans, chosen as acceptable under navigated and deliverable conditions resulted in similar rectal sparing compared with standard optimization (33.7 ± 1.8 Gy vs 35.5 ± 4.2 Gy, p = 0.117). The dose differences between navigated and deliverable MCO plans increased as higher priority was placed on rectal avoidance. If the best possible deliverable MCO was chosen, a significant reduction in rectal dose was observed in comparison with standard optimization (30.6 ± 1.4 Gy vs 35.5 ± 4.2 Gy, p = 0.047). Improvements were, however, to some extent, at the expense of less conformal dose distributions, which resulted in significantly higher doses to the bladder for 2 of the 3 tolerance levels. In conclusion, similar IMRT plans can be created for patients with prostate cancer using MCO compared with standard optimization. Limitations exist within MCO regarding conversion of navigated plans to deliverable apertures, particularly for plans that emphasize avoidance of critical structures. Minimizing these differences would result in better quality treatments for patients with prostate cancer who were treated with radiotherapy using MCO plans.« less

Flexible long-chain-linker constructed Ni-based metal-organic frameworks with 1D helical channel and their pseudo-capacitor behavior studies

NASA Astrophysics Data System (ADS)

Wang, Kuaibing; Wang, Zikai; Wang, Xin; Zhou, Xueqin; Tao, Yuehong; Wu, Hua

2018-02-01

Two novel and isostructural Ni-based MOFs with topological symbol of 422·54·62, namely [Ni2(TATB)2(L)2(H2O)], have successfully synthesized, where L is the flexibly N-donor bid (1,10-bisimidazoledecane) or btd (1,10-bistriazoledecane) linker and TATB is the deprotonation mode from 4,4‧,4″-s-triazine-2,4,6-triyl-tribenzoic acid (H3TATB). Two types of left- and right-handed helical channels with mean diameter of 11 Å results in large void space in 3D network. When directly use as electrode materials, the as-synthesized Ni-MOFs single-crystal electrodes behave as pseudo-capacitor and deliver high gravimetric capacitance with superior energy deliverable ability and cycling stability. For example, the maximum gravimetric capacitance is 705 F g-1 with the energy density of 29.6 Wh kg-1 at a current density of 1 A g-1. Even after 5000 continuous cycles, the capacitance retention maintains at 92.1%. The good electrochemical performance should be ascribed to the 1D helical channels facilitating the diffusion of OH-. Furthermore, the low bulk solution (0.46 and 0.50 Ω) and charge-transfer resistances accelerate the contact between OH- and active species in the electrode, and consequently result in efficiency Faradaic reaction. This work opens a new way for the directly application of 3D topological MOFs single-crystal with novel interior structures especially porous and channel-like architectures in electronic energy storage field.

Countrywide digital elevation models for the Islamic Republic of Mauritania—SRTM and ASTER (phase V, deliverable 65): Chapter F in Second projet de renforcement institutionnel du secteur minier de la République Islamique de Mauritanie (PRISM-II)

USGS Publications Warehouse

Lee, Gregory K.

2015-01-01

A digital elevation model (DEM) of the entire country of the Islamic Republic of Mauritania was produced using Shuttle Radar Topography Mission (SRTM) data as required for deliverable 65 of the contract. In addition, because of significant recent advancements of availability, seamlessness, and validity of Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER) global elevation data, the U.S. Geological Survey (USGS) extended its efforts to include a higher resolution countrywide ASTER DEM as value added to the required Deliverable 63, which was limited to five areas within the country. Both SRTM and ASTER countrywide DEMs have been provided in ERDAS Imagine (.img) format that is also directly compatible with ESRI ArcMap, ArcGIS Explorer, and other GIS applications.

75 FR 35513 - Application of Schuman Aviation Company Ltd. D/B/A Makani Kai Helicopters D/B/A Ko Olina...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-22

... directing all interested persons to show cause why it should not issue an order finding Schuman Aviation... DEPARTMENT OF TRANSPORTATION Office of the Secretary Application of Schuman Aviation Company Ltd.... Kurland, Assistant Secretary, for Aviation and International Affairs. [FR Doc. 2010-15028 Filed 6-21-10; 8...

Resource Recovery Technology Application Document.

DTIC Science & Technology

1982-06-01

B-6 Electrostatic Precipitator (APC-C) ......................B-1O Venturi Scrubber (APC D) B-15 C Combustion Equipment (CE) C-1 Modular... Scrubber APC-D P. 1 of 4 CONTROLIII COMPONENT DESCRIPTION Types Available - Competing Components Type a. Venturi e. Moving bed Venturi b. Flooded disc f...Clean Gas to Demister (Used Separate Liquid from Gas Stream) / F C Scrubber Wall Liquid Inlet D Scrubber Liquid at Venturi Throat Inlet B E Venturi

Texture analysis on the fluence map to evaluate the degree of modulation for volumetric modulated arc therapy

DOE Office of Scientific and Technical Information (OSTI.GOV)

Park, So-Yeon; Institute of Radiation Medicine, Seoul National University Medical Research Center, Seoul 110-744; Biomedical Research Institute, Seoul National University College of Medicine, Seoul 110-744

Purpose: Texture analysis on fluence maps was performed to evaluate the degree of modulation for volumetric modulated arc therapy (VMAT) plans. Methods: A total of six textural features including angular second moment, inverse difference moment, contrast, variance, correlation, and entropy were calculated for fluence maps generated from 20 prostate and 20 head and neck VMAT plans. For each of the textural features, particular displacement distances (d) of 1, 5, and 10 were adopted. To investigate the deliverability of each VMAT plan, gamma passing rates of pretreatment quality assurance, and differences in modulating parameters such as multileaf collimator (MLC) positions, gantrymore » angles, and monitor units at each control point between VMAT plans and dynamic log files registered by the Linac control system during delivery were acquired. Furthermore, differences between the original VMAT plan and the plan reconstructed from the dynamic log files were also investigated. To test the performance of the textural features as indicators for the modulation degree of VMAT plans, Spearman’s rank correlation coefficients (r{sub s}) with the plan deliverability were calculated. For comparison purposes, conventional modulation indices for VMAT including the modulation complexity score for VMAT, leaf travel modulation complexity score, and modulation index supporting station parameter optimized radiation therapy (MI{sub SPORT}) were calculated, and their correlations were analyzed in the same way. Results: There was no particular textural feature which always showed superior correlations with every type of plan deliverability. Considering the results comprehensively, contrast (d = 1) and variance (d = 1) generally showed considerable correlations with every type of plan deliverability. These textural features always showed higher correlations to the plan deliverability than did the conventional modulation indices, except in the case of modulating parameter differences. The r{sub s} values of contrast to the global gamma passing rates with criteria of 2%/2 mm, 2%/1 mm, and 1%/2 mm were 0.536, 0.473, and 0.718, respectively. The respective values for variance were 0.551, 0.481, and 0.688. In the case of local gamma passing rates, the r{sub s} values of contrast were 0.547, 0.578, and 0.620, respectively, and those of variance were 0.519, 0.527, and 0.569. All of the r{sub s} values in those cases were statistically significant (p < 0.003). In the cases of global and local gamma passing rates, MI{sub SPORT} showed the highest correlations among the conventional modulation indices. For global passing rates, r{sub s} values of MI{sub SPORT} were −0.420, −0.330, and −0.632, respectively, and those for local passing rates were −0.455, −0.490 and −0.502. The values of r{sub s} of contrast, variance, and MI{sub SPORT} with the MLC errors were −0.863, −0.828, and 0.795, respectively, all with statistical significances (p < 0.001). The correlations with statistical significances between variance and dose-volumetric differences were observed more frequently than the others. Conclusions: The contrast (d = 1) and variance (d = 1) calculated from fluence maps of VMAT plans showed considerable correlations with the plan deliverability, indicating their potential use as indicators for assessing the degree of modulation of VMAT plans. Both contrast and variance consistently showed better performance than the conventional modulation indices for VMAT.« less

76 FR 12095 - Monroe Gas Storage Company, LLC; Notice of Application

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-04

... Storage Company, LLC; Notice of Application Take notice that on February 18, 2011, Monroe Gas Storage... Monroe Gas Storage Project. Specifically, through this Application, Monroe seeks authorization to (1...) of high-deliverability working gas storage capacity, with about 4.46 Bcf of base gas. Nor is any...

Pilot Aircraft Interface Objectives/Rationale

NASA Technical Reports Server (NTRS)

Shively, Jay

2010-01-01

Objective: Database and proof of concept for guidelines for GCS compliance a) Rationale: 1) Provide research test-bed to develop guidelines. 2) Modify GCS for NAS Compliance to provide proof of concept. b) Approach: 1) Assess current state of GCS technology. 2) Information Requirements Definition. 3) SME Workshop. 4) Modify an Existing GCS for NAS Compliance. 5) Define exemplar UAS (choose system to develop prototype). 6) Define Candidate Displays & Controls. 7) Evaluate/ refine in Simulations. 8) Demonstrate in flight. c) Deliverables: 1) Information Requirements Report. 2) Workshop Proceedings. 3) Technical Reports/ papers on Simulations & Flight Demo. 4) Database for guidelines.

Radiation Hardened Telerobotic Dismantling System Development Final Report CRADA No. TC-1340-96

DOE Office of Scientific and Technical Information (OSTI.GOV)

Smith, C.; Lightman, A.

This project was a collaborative effort between the University of California, LLNL and RedZone Robotics, Inc. for the development of radiation-hardened telerobotic dismantling systems for use in applications such as nuclear facility remediation, nuclear accident response, and Chemobyltype remediation. The project supported the design, development, fabrication and testing of a Ukrainian robotic systems. The project was completed on time and within budget. All deliverables were completed. The final project deliverables were consistent with the plans developed in the original project with the exception that the fabricated systems remained in Ukraine.

Design Investigation of a Laminated Waveguide Fed Multi-Band DRA for Military Applications

NASA Astrophysics Data System (ADS)

Kumar, Pramod; Dwari, Santanu; Singh, Shailendra; Agrawal, N. K.

2017-12-01

In this paper a laminated waveguide fed DR Antenna is investigated. It can use for moderate power military applications. Cylindrical DRA is excited by two closely spaced asymmetric longitudinal slots on the broad wall of the laminated cavity are responsible for producing three different frequency bands. Parametric study of slots has been done with the help of commercial software ANSOFT HFSS. All the bands have sharp rejection. The final model of the antenna is simulated, fabricated and experimentally measured. Measured results are in quite accordant with design results. SIW feeding structures have small losses, moderate power handling capacity, low costs, compact sizes and can be seamlessly integrated with planar circuits. At all the bands 9.76 GHz, 10.53 GHz and 11.8 GHz resonant frequency, the antenna shows 56 MHz, 160 MHz, and 250 MHz impedance bandwidth (for VSWR<2) with 6 dB,6.2 dB and 6.8 dB gain respectively. Simulated and measured results reveal outstanding performance with a cross-polar level of 29 dB lower than that of the co-polar level at 9.76 GHz, the cross-polar level of 32 dB lower than that of the co-polar level at 10.53, GHz, and similarly cross-polar level of 30 dB lower than that of the co-polar level at 11.8 GHz.

20 CFR 638.801 - Staff training.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 20 Employees' Benefits 3 2012-04-01 2012-04-01 false Staff training. 638.801 Section 638.801... TITLE IV-B OF THE JOB TRAINING PARTNERSHIP ACT Administrative Provisions § 638.801 Staff training. The... office, and deliverer staff. ...

20 CFR 638.801 - Staff training.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 20 Employees' Benefits 3 2011-04-01 2011-04-01 false Staff training. 638.801 Section 638.801... TITLE IV-B OF THE JOB TRAINING PARTNERSHIP ACT Administrative Provisions § 638.801 Staff training. The... office, and deliverer staff. ...

20 CFR 638.801 - Staff training.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Staff training. 638.801 Section 638.801... TITLE IV-B OF THE JOB TRAINING PARTNERSHIP ACT Administrative Provisions § 638.801 Staff training. The... office, and deliverer staff. ...

Beam commissioning and measurements validating the beam model in a new TPS that converts helical tomotherapy plans to step-and-shoot IMRT plans.

PubMed

Petersson, Kristoffer; Ceberg, Crister; Engström, Per; Knöös, Tommy

2011-01-01

A new type of treatment planning system called SHAREPLAN has been studied, which enables the transfer of treatment plans generated for helical tomotherapy delivery to plans that can be delivered on C-arm linacs. The purpose is to ensure continuous patient treatment during periods of unscheduled downtime for the TomoTherapy unit, particularly in clinics without a backup unit. The purpose of this work was to verify that the plans generated in this novel planning system are deliverable and accurate. The work consists primarily of beam commissioning, verification of the beam model, and measurements verifying that generated plans are deliverable with sufficient accuracy. The beam commissioning process involves input of general geometric properties of the modeled linac, profiles and depth dose curves for a specific photon nominal energy (6 MV), and the automated modeling of other beam properties. Some manual tuning of the beam model is required. To evaluate its accuracy, the confidence limit concept [J. Venselaar et al., "Tolerances for the accuracy of photon beam dose calculations of treatment planning systems," Radiother. Oncol. 60, 191-201 (2001)] was used, which is a method supported by ESTRO. Measurements were conducted with a 2D diode array at the commissioned linac as a final check of the beam model and to evaluate whether the generated plans were deliverable and accurate. The comparison and evaluation of calculated data points and measured data according to the method applied confirmed the accuracy of the beam model. The profiles had a confidence limit of 1.1% and the depth dose curves had a confidence limit of 1.7%, both of which were well below the tolerance limit of 2%. Plan specific QC measurements and evaluation verified that different plans generated in the TPS were deliverable with sufficient accuracy at the commissioned linac, as none of the 160 beams for the 20 different plans evaluated had a fraction of approved data points below 90%, the local clinical approval criterion for delivery QA measurements. This study is a validation of the new TPS as it verifies that the generated plans are deliverable at a commissioned linac with adequate accuracy. A thorough investigation of the treatment plan quality will require a separate study. The TPS is proving to be a useful and time-saving complement, especially for clinics having a single unit for helical delivery among its conventional linacs.

Resource Conservation and Recovery Act, Part B Permit Application [for the Waste Isolation Pilot Plant (WIPP)]. Volume 6, Chapter D, Appendices D4--D13: Revision 1.0

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1991-12-31

This report (Vol. 6) for the WIPP facility contains appendices on the following information: Site characterization; general geology; ecological monitoring; and chemical compatibility of waste forms and container materials.

SU-F-P-64: The Impact of Plan Complexity Parameters On the Plan Quality and Deliverability of Volumetric Modulated Arc Therapy with Canonical Correlation Analysis

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jin, X; Yi, J; Xie, C

Purpose: To evaluate the impact of complexity indices on the plan quality and deliverability of volumetric modulated arc therapy (VMAT), and to determine the most significant parameters in the generation of an ideal VMAT plan. Methods: A multi-dimensional exploratory statistical method, canonical correlation analysis (CCA) was adopted to study the correlations between VMAT parameters of complexity, quality and deliverability, as well as their contribution weights with 32 two-arc VMAT nasopharyngeal cancer (NPC) patients and 31 one-arc VMAT prostate cancer patients. Results: The MU per arc (MU/Arc) and MU per control point (MU/CP) of NPC were 337.8±25.2 and 3.7±0.3, respectively, whichmore » were significantly lower than those of prostate cancer patients (MU/Arc : 506.9±95.4, MU/CP : 5.6±1.1). The plan complexity indices indicated that two-arc VMAT plans were more complex than one-arc VMAT plans. Plan quality comparison confirmed that one-arc VMAT plans had a high quality than two-arc VMAT plans. CCA results implied that plan complexity parameters were highly correlated with plan quality with the first two canonical correlations of 0.96, 0.88 (both p<0.001) and significantly correlated with deliverability with the first canonical correlation of 0.79 (p<0.001), plan quality and deliverability was also correlated with the first canonical correlation of 0.71 (p=0.02). Complexity parameters of MU/CP, segment area (SA) per CP, percent of MU/CP less 3 and planning target volume (PTV) were weighted heavily in correlation with plan quality and deliveability . Similar results obtained from individual NPC and prostate CCA analysis. Conclusion: Relationship between complexity, quality, and deliverability parameters were investigated with CCA. MU, SA related parameters and PTV volume were found to have strong effect on the plan quality and deliverability. The presented correlation among different quantified parameters could be used to improve the plan quality and the efficiency of the radiotherapy process when creating a complex VMAT plan.« less

Contribution of 3D printing to mandibular reconstruction after cancer.

PubMed

Dupret-Bories, A; Vergez, S; Meresse, T; Brouillet, F; Bertrand, G

2018-04-01

Three-dimensional (3D) printing is booming in the medical field. This technology increases the possibilities of personalized treatment for patients, while lowering manufacturing costs. To facilitate mandibular reconstruction with fibula free flap, some companies propose cutting guides obtained by CT-guided moulding. However, these guides are prohibitively expensive (€2,000 to €6,000). Based on a partnership with the CNRS, engineering students and a biomedical company, the authors have developed cutting guides and 3D-printed mandible templates, deliverable in 7days and at a lower cost. The novelty of this project is the speed of product development at a significantly lower price. In this technical note, the authors describe the logistic chain of production of mandible templates and cutting guides, as well as the results obtained. The goal is to allow access to this technology to all patients in the near future. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

Application of fuzzy logic-neural network based reinforcement learning to proximity and docking operations: Translational controller results

NASA Technical Reports Server (NTRS)

Jani, Yashvant

1992-01-01

The reinforcement learning techniques developed at Ames Research Center are being applied to proximity and docking operations using the Shuttle and Solar Maximum Mission (SMM) satellite simulation. In utilizing these fuzzy learning techniques, we also use the Approximate Reasoning based Intelligent Control (ARIC) architecture, and so we use two terms interchangeable to imply the same. This activity is carried out in the Software Technology Laboratory utilizing the Orbital Operations Simulator (OOS). This report is the deliverable D3 in our project activity and provides the test results of the fuzzy learning translational controller. This report is organized in six sections. Based on our experience and analysis with the attitude controller, we have modified the basic configuration of the reinforcement learning algorithm in ARIC as described in section 2. The shuttle translational controller and its implementation in fuzzy learning architecture is described in section 3. Two test cases that we have performed are described in section 4. Our results and conclusions are discussed in section 5, and section 6 provides future plans and summary for the project.

ERLN WebEDR Fact Sheet

EPA Pesticide Factsheets

The Web-based Electronic Data Review (WebEDR) application performs automated data evaluation on ERLN electronic data deliverables (EDDs). It uses test derived from the National Functional Guidelines combined with method-defined limits to measure data.

48 CFR 211.274-6 - Contract clauses.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 48 Federal Acquisition Regulations System 3 2013-10-01 2013-10-01 false Contract clauses. 211.274-6 Section 211.274-6 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM... subassemblies, components, or parts embedded within deliverable items. (4) Use the clause with its Alternate I...

48 CFR 211.274-6 - Contract clauses.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 48 Federal Acquisition Regulations System 3 2012-10-01 2012-10-01 false Contract clauses. 211.274-6 Section 211.274-6 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM... subassemblies, components, or parts embedded within deliverable items. (4) Use the clause with its Alternate I...

The milk delivery chain and presence of Brucella spp. antibodies in bulk milk in Uganda.

PubMed

Rock, Kim Toeroek; Mugizi, Denis Rwabiita; Ståhl, Karl; Magnusson, Ulf; Boqvist, Sofia

2016-06-01

This study examined the influence of informal milk delivery chains on the risk of human exposure to Brucella spp. through milk consumption in two regions of Uganda (Gulu and Soroti Districts). The work involved describing milk delivery chains, investigating brucellosis awareness amongst milk deliverers and determining the presence of Brucella spp. antibodies in cattle milk on delivery to primary collection points (boiling points and dairies). Milk samples (n = 331) were collected from deliverers at primary collection points and from street vendors at point of sale and analysed using indirect enzyme-linked immunosorbent assay (I-ELISA). A written questionnaire was used to collect data from deliverers (n = 279) on their milk delivery chains and their brucellosis awareness. The most common delivery points in Gulu District were small dairies and in Soroti District boiling points. The presence of Brucella spp. antibodies in milk samples was higher in Soroti (40 %) than in Gulu (11 %) (P < 0.0001). There are possible public health risk consequences of this finding as 42 % of deliverers in Soroti District reported drinking raw milk, compared with 15 % in Gulu District (P < 0.0001). Awareness of brucellosis was low, with 70 % of all milk deliverers reporting not having heard of the disease or the bacterium. Application of quality controls for milk (colour and odour) along the delivery chain varied depending upon supply and demand. This study provides evidence of the diversity of informal milk markets in low-income countries and of the potential public health risks of consuming unpasteurised milk. These results can be useful to those planning interventions to reduce brucellosis.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sleaford, Brad W.; Hurst, Aaron M.

This report describes the measurement, evaluation and incorporation of new -ray spectroscopic data into the Evaluated Nuclear Data File (ENDF) for nonproliferation applications. Analysis and processing techniques are described along with key deliverables that have been met over the course of this project. A total of nine new ENDF libraries have been submitted to the National Nuclear Data Center at the Brookhaven National Laboratory and are now available in the ENDF/B-VIII.beta2 release. Furthermore, this project has led to more than ten peer-reviewed publications and provided theses for ve graduate students. This project is a component of the NA-22 venture collaborationmore » on \\Correlated Nuclear Data in Fission Events" (LA14-V-CorrData-PD2Jb).« less

Photothermal Deoxygenation of Graphene Oxide for Distributed Ignition and Patterning Applications (Postprint)

DTIC Science & Technology

2010-01-01

5] B. Brodie, Ann. Chim. Phys. 1855, 45, 351. [6] D. Dikin , S. Stankovich, E. J. Zimney, R. D. Piner, H. B. Dommett, G. Evmenenko, S. T. Nguyen, R. S... Dikin , R. D. Piner, K. A. Kohlhaas, A. Kleinhammes, Y. Jia, Y. Wu, S. T. Nguyen, R. S. Ruoff, Carbon 2007, 45, 1558. [9] S. Stankovich, R. D. Piner, X...Lett. 2007, 7, 3499. [16] S. Stankovich, D. A. Dikin , G. H. B. Dommett, K. M. Kohlhaas, E. J. Zimney, E. A. Stach, R. D. Piner, S. T. Nguyen, R. S

Technology and Application of Indium Phosphide and Related Semiconductors

DTIC Science & Technology

1989-03-01

Application and Insertion, GED-L 80/84-9, Oct 1984 1.2: M. Y. Yen , B. F. Levine, C. G. Bethea, K. K. Choi, and A. Y. Cho, Appl. Phys. Lett. 50 (1987) 927...Schlachetzki, Solid-State Electron. 28 (1985) 299 40 IV,A,5: F. B. Fank, J. D. Crowley, and J. J. Berenz, Microwave Journal, June 1979, p. 86 IV,A.6...Ser. 79 (1986) 703 IV,CIb.6: N. K. Dutta, S. G. Napholtz, R. Yen , R. L. Brown, T. M. Shen, N. A. Olsson, and D. C. Craft, Appl. Phys. Lett. 46 (1985

26 CFR 1.279-5 - Rules for application of section 279(b).

Code of Federal Regulations, 2012 CFR

2012-04-01

... section 279(b). (a) Taxable years to which applicable—(1) First year of disallowance. Under section 279(d... subsequent taxable years. (b) Time of determination—(1) In general. The determination of whether an... an affiliated group (see section 279(g) and § 1.279-6 for rules regarding application of section 279...

26 CFR 1.279-5 - Rules for application of section 279(b).

Code of Federal Regulations, 2011 CFR

2011-04-01

... section 279(b). (a) Taxable years to which applicable—(1) First year of disallowance. Under section 279(d... subsequent taxable years. (b) Time of determination—(1) In general. The determination of whether an... an affiliated group (see section 279(g) and § 1.279-6 for rules regarding application of section 279...

26 CFR 1.279-5 - Rules for application of section 279(b).

Code of Federal Regulations, 2013 CFR

2013-04-01

... section 279(b). (a) Taxable years to which applicable—(1) First year of disallowance. Under section 279(d... subsequent taxable years. (b) Time of determination—(1) In general. The determination of whether an... an affiliated group (see section 279(g) and § 1.279-6 for rules regarding application of section 279...

Development and Application of a Tendon Prosthesis for Early Functional Restoration of the Hand.

DTIC Science & Technology

1975-09-01

AD-ARSA 323 JEFFERSON MEDICAL COLL PHILADELP HIA PA F/6 6/5 DEVELOFHNT AND APPLICATION OF A TENDON PROSTHESIS FOR EARLY FU--ETCU, SEP 75 .1 M HUNTER...THIS SHEET S LEVELINETR S DEVELOPEN AND APPLICATION OF A TENDON PROSTESIS FOR EARLY FUNCTIONAL RTORATION OF THE HAND DOCUMENT IDENTIFICATION...OF A TENDON PROSTHESIS * (B.l FOR EARLY FUNCTIONAL RESTORATION OF THE HArD ANNUAL REPORT by James M. Hunter, M.D. September 1975 (For the period 1 July

3D Bioprinted Artificial Trachea with Epithelial Cells and Chondrogenic-Differentiated Bone Marrow-Derived Mesenchymal Stem Cells.

PubMed

Bae, Sang-Woo; Lee, Kang-Woog; Park, Jae-Hyun; Lee, JunHee; Jung, Cho-Rok; Yu, JunJie; Kim, Hwi-Yool; Kim, Dae-Hyun

2018-05-31

Tracheal resection has limited applicability. Although various tracheal replacement strategies were performed using artificial prosthesis, synthetic stents and tissue transplantation, the best method in tracheal reconstruction remains to be identified. Recent advances in tissue engineering enabled 3D bioprinting using various biocompatible materials including living cells, thereby making the product clinically applicable. Moreover, clinical interest in mesenchymal stem cell has dramatically increased. Here, rabbit bone marrow-derived mesenchymal stem cells (bMSC) and rabbit respiratory epithelial cells were cultured. The chondrogenic differentiation level of bMSC cultured in regular media (MSC) and that in chondrogenic media (d-MSC) were compared. Dual cell-containing artificial trachea were manufactured using a 3D bioprinting method with epithelial cells and undifferentiated bMSC (MSC group, n = 6) or with epithelial cells and chondrogenic-differentiated bMSC (d-MSC group, n = 6). d-MSC showed a relatively higher level of glycosaminoglycan (GAG) accumulation and chondrogenic marker gene expression than MSC in vitro. Neo-epithelialization and neo-vascularization were observed in all groups in vivo but neo-cartilage formation was only noted in d-MSC. The epithelial cells in the 3D bioprinted artificial trachea were effective in respiratory epithelium regeneration. Chondrogenic-differentiated bMSC had more neo-cartilage formation potential in a short period. Nevertheless, the cartilage formation was observed only in a localized area.

20 CFR 638.539 - Complaints and disputes.

Code of Federal Regulations, 2010 CFR

2010-04-01

....539 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF LABOR JOB CORPS PROGRAM UNDER TITLE IV-B OF THE JOB TRAINING PARTNERSHIP ACT Center Operations § 638.539 Complaints and disputes. (a) Center and other deliverer grievance procedures. Each center operator or other Job Corps...

Polarimetric Calibration and Assessment of GF-3 Images in Steppe

NASA Astrophysics Data System (ADS)

Chang, Y.; Yang, J.; Li, P.; Shi, L.; Zhao, L.

2018-04-01

The GaoFen-3 (GF-3) satellite is the first fully polarimetric synthetic aperture radar (PolSAR) satellite in China. It has three fully polarimetric imaging modes and is available for many applications. The system has been taken on several calibration experiments after the launch in Inner Mongolia by the Institute of Electronics, Chinese Academy of Sciences (IECAS), and the polarimetric calibration (PolCAL) strategy of GF-3 are also improved. Therefore, it is necessary to assess the image quality before any further applications. In this paper, we evaluated the polarimetric residual errors of GF-3 images that acquired in July 2017 in a steppe site. The results shows that the crosstalk of these images varies from -36 dB to -46 dB, and the channel imbalance varies from -0.43 dB to 0.55 dB with angle varying from -1.6 to 3.6 degree. We also made a PolCAL experiment to restrain the polarimetric distortion afterwards, and the polarimetric quality of the image got better after the PolCAL processing.

Project deliverables - a waste of time or a chance for knowledge transfer and dissemination?

NASA Astrophysics Data System (ADS)

Walter, Sylvia

2016-04-01

Deliverables are a common tool to measure a distinct output of a project. They should be meaningful in terms of the project's objectives and are normally constituted by e.g. a written report or document, a developed tool or software, an organized training or conference. They can be scientific or technical. The number of deliverables must be reasonable and commensurate to the project and its content. Deliverables as contractual obligations are often time consuming and often seen as a waste of "research" time, as one more administrative task without any use. However, deliverables are needed to verify the progress of a project and to convince the sponsor that the project is going in the right direction and the money well-invested. The presentation will deal with the question on how to use a deliverable in a profitable way for the project and what are the possibilities of use.

Parameter Estimation Versus Homogenization Techniques in Time-Domain Characterization of Composite Dielectrics

DTIC Science & Technology

2006-08-22

H. T. Banks, V. A. Bokil, D. Cioranescu, N. L. Gibson, G. Griso, and B. Miara , Homogeniza- tion of periodically varying coefficients in...Terahertz signals, Nonlinear Analysis: Real World Applications, 6 (2005), 381–416. [6] A. Bossavit, G. Griso, and B. Miara , Modeling of periodic

Reliability Modeling Development and Its Applications for Ceramic Capacitors with Base-Metal Electrodes (BMEs)

NASA Technical Reports Server (NTRS)

Liu, Donhang

2014-01-01

This presentation includes a summary of NEPP-funded deliverables for the Base-Metal Electrodes (BMEs) capacitor task, development of a general reliability model for BME capacitors, and a summary and future work.

30 CFR 715.10 - Information collection.

Code of Federal Regulations, 2014 CFR

2014-07-01

... collection requirements contained in 30 CFR 715.13(d); 715.17 (b)(1)(v) and (j)(3); 715.18(b) (2) and (6... performance standards in section 515(b)(2) of P.L. 95-87 and are applicable during the initial regulatory...

30 CFR 715.10 - Information collection.

Code of Federal Regulations, 2013 CFR

2013-07-01

... collection requirements contained in 30 CFR 715.13(d); 715.17 (b)(1)(v) and (j)(3); 715.18(b) (2) and (6... performance standards in section 515(b)(2) of P.L. 95-87 and are applicable during the initial regulatory...

A survey of music therapists' work with speech-language pathologists and experiences with augmentative and alternative communication.

PubMed

McCarthy, John; Geist, Kamile; Zojwala, Rashida; Schock, Molly Z

2008-01-01

Although music therapists may work with a variety of professionals in interdisciplinary teams, there is a lack of information about the specific nature of their work with speech-language pathologists (SLPs). Using an Internet-based tool, Board Certified Music Therapists (n = 1834, 1675 deliverable) were surveyed regarding their work with speech-language pathologists and experiences with augmentative and alternative communication (AAC). Specifically, participants were asked about: (a) demographics; (b) populations worked with professionally; (c) past and present work with speech-language pathologists; (d) goals addressed; (e) benefits and challenges encountered; and (f) work with AAC. Responses (N = 847) indicated the majority of participants (73.6%) had worked with SLPs at some point in various roles and in various settings. Fewer participants reported currently working with SLPs (42.8%), although 50.1% reported currently working with someone requiring some form of AAC. Participants reported a mean level of expertise with AAC of 3.9 on a scale of 1-7. Sharing knowledge was noted as a top benefit of working with SLPs, while scheduling was reported as the most frequent challenge. Other benefits and challenges as well as future research directions are discussed.

Innovative Techniques for the Production of Low Cost 2D Laser Diode Arrays

DTIC Science & Technology

1991-11-26

electrically isolated and liquid cooled. (Deliverables: 5 5-bar arrays.) The following global issues not mentioned above will be investigated...house facet coating station. All global issues mentioned in Section 2.0 will be addressed and continuously investigated during this program. Very

Segmental Neogenesis of the Dog Esophagus Utilizing a Biodegradable Polymer Framework

DTIC Science & Technology

1988-12-20

Dental (If applicable) US Army Medical Research & Development Research I SGRD-UDR-B Command (HQDA-IS) 6c. ADDRESS (City, State, and ZIP Code) 7b. ADDRESS...Marvin F. Grower, D.D.S., Ph.D. Emery A. Russell, Jr., D.D.S., M.S. Duane E. Cutright, D.D.S., M.S., Ph.D. U. S. Army Institute of Dental Research...the polymer solutions with a #152 dental atomizer (DeVilbiss Corp.) using 20-30 psi of nitrogen as a prdpellant at a distance of 10-18 inches from a

48 CFR 227.7103-6 - Contract clauses.

Code of Federal Regulations, 2010 CFR

2010-10-01

..., DEPARTMENT OF DEFENSE GENERAL CONTRACTING REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Rights in Technical Data 227.7103-6 Contract clauses. (a) Use the clause at 252.227-7013, Rights in Technical Data... technical data to the Government. Do not use the clause when the only deliverable items are computer...

Assessment of Body Weight Standards in Male and Female Army Recruits

DTIC Science & Technology

1989-12-29

OF ENVIRONMENTAL MEDICINE Natick, Massachusetts DTIC` h tj1LECTF’S&I L19 1gu A p p to@ 4 d lo t p u b li c f hlo .. d t t hb u lio " uY lim i led...RECRUITS K.E. Fried’, Pit.D. J.A. Vogsl, Ph.D. M.W. Bovee iB.H. Jones, M.D. Exercise Physiology Division US Army Research Institute of Environmental ...MONITORING ORGANIZATION U.S. Army Research Institute (If applicable) of Environmental Medicine SGRD-UE-PH 6c. ADDRESS (City, State, and ZIPCodte 7b

Microstrucutral Modeling of Hot Spot and Failure Mechanisms in RDX Energetic Aggregates

DTIC Science & Technology

2014-01-01

with applications to disposable blood pressure cuffs . He graduated cum laude with a Bachelors of Science degree in Mechanical Engineering in May of...35 Figure 4.2. (a) Rotation , (b) Normal Stress, (c) Pressure, and (d...39 Figure 4.6. (a) Rotation , (b) Normal Stress, (c) Pressure, and (d) Accumulated plastic shear

Performance Testing of a Microfabricated Propulsion System for Nanosatellite Applications (POSTPRINT)

DTIC Science & Technology

2005-04-22

References [1] Janson S, Helvajian H and Robinson E 1993 The concept of nanosatellite for revolutionary, low-cost space systems 44th International...technologies J. Micromech. Microeng. 8 54–6 [4] Helvajian H 1997 Microengineering Technology for Space Systems (Reston, VA: AIAA) [5] Ketsdever A D 2000 System...nanosatellite applications (POSTPRINT) 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Andrew D. Ketsdever (AFRL/PRSA); Riki H . Lee and

Understanding metastable phase transformation during crystallization of RDX, HMX and CL-20: experimental and DFT studies.

PubMed

Ghosh, Mrinal; Banerjee, Shaibal; Shafeeuulla Khan, Md Abdul; Sikder, Nirmala; Sikder, Arun Kanti

2016-09-14

Multiphase growth during crystallization severely affects deliverable output of explosive materials. Appearance and incomplete transformation of metastable phases are a major source of polymorphic impurities. This article presents a methodical and molecular level understanding of the metastable phase transformation mechanism during crystallization of cyclic nitramine explosives, viz. RDX, HMX and CL-20. Instantaneous reverse precipitation yielded metastable γ-HMX and β-CL-20 which undergo solution mediated transformation to the respective thermodynamic forms, β-HMX and ε-CL-20, following 'Ostwald's rule of stages'. However, no metastable phase, anticipated as β-RDX, was evidenced during precipitation of RDX, which rather directly yielded the thermodynamically stable α-phase. The γ→β-HMX and β→ε-CL-20 transformations took 20 and 60 minutes respectively, whereas formation of α-RDX was instantaneous. Density functional calculations were employed to identify the possible transition state conformations and to obtain activation barriers for transformations at wB97XD/6-311++G(d,p)(IEFPCM)//B3LYP/6-311G(d,p) level of theory. The computed activation barriers and lattice energies responsible for transformation of RDX, HMX and CL-20 metastable phases to thermodynamic ones conspicuously supported the experimentally observed order of phase stability. This precise result facilitated an understanding of the occurrence of a relatively more sensitive and less dense β-CL-20 phase in TNT based melt-cast explosive compositions, a persistent and critical problem unanswered in the literature. The crystalline material recovered from such compositions revealed a mixture of β- and ε-CL-20. However, similar compositions of RDX and HMX never showed any metastable phase. The relatively long stability with the highest activation barrier is believed to restrict complete β→ε-CL-20 transformation during processing. Therefore a method is suggested to overcome this issue.

Market Assessment For Traveler Services, A Choice Modeling Study Phase Iii, Fast-Trac Deliverable, #16B: Final Choice Modeling Report

DOT National Transportation Integrated Search

1999-02-12

FAST-TRAC : THIS REPORT DESCRIBES THE CHOICE MODEL STUDY OF THE FAST-TRAC (FASTER AND SAFER TRAVEL THROUGH TRAFFIC ROUTING AND ADVANCED CONTROLS) OPERATIONAL TEST IN SOUTHEAST MICHIGAN. CHOICE MODELING IS A STATED-PREFERENCE APPROACH IN WHICH RESP...

76 FR 56189 - Symbiotics, LLC; Notice of Application Accepted for Filing, Soliciting Motions to Intervene and...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-12

.... b. Project No.: 12965-002. c. Date filed: March 25, 2011. d. Applicant: Symbiotics, LLC. e. Name of... brief comments up to 6,000 characters, without prior registration, using the eComment system at http...: Kimberly D. Bose, Secretary, Federal Energy Regulatory Commission, 888 First Street, NE., Washington, DC...

Design and Evaluation of Scour for Bridges Using HEC-18 : technical brief.

DOT National Transportation Integrated Search

2017-07-01

This project developed a new approach for evaluating erosive scour at New Jersey bridges over non-tidal waterways. The main deliverable was the Scour Evaluation Model (SEM), which offers new analysis procedures, while still retaining the applicable p...

Comparative Packaging Study

NASA Technical Reports Server (NTRS)

Perchonok, Michele; Antonini, David

2008-01-01

This viewgraph presentation describes a comparative packaging study for use on long duration space missions. The topics include: 1) Purpose; 2) Deliverables; 3) Food Sample Selection; 4) Experimental Design Matrix; 5) Permeation Rate Comparison; and 6) Packaging Material Information.

49 CFR 22.25 - Lender deliverables and delivery schedule.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 1 2010-10-01 2010-10-01 false Lender deliverables and delivery schedule. 22.25 Section 22.25 Transportation Office of the Secretary of Transportation SHORT-TERM LENDING PROGRAM (STLP) Participating Lenders § 22.25 Lender deliverables and delivery schedule. All Participating Lenders must adhere...

Crystalline basement map of Mauritania derived from filtered aeromagnetic data (deliverable 54_1), Aeromagnetic and geological structure map of Mauritania (phase V, deliverable 54_2), Maximum depth to basement map of Mauritania derived from Euler analysis of Aeromagnetic data (phase V, deliverable 54_3), and color composite image of radioelement data (added value): Chapter B1 in Second projet de renforcement institutionnel du secteur minier de la République Islamique de Mauritanie (PRISM-II)

USGS Publications Warehouse

Finn, Carol A.; Horton, John D.

2015-01-01

This report contains the USGS results of the PRISM-II Mauritania Minerals Project and is presented in cooperation with the Ministry of Petroleum, Energy, and Mines of the Islamic Republic of Mauritania. The Report is composed of separate chapters consisting of multidisciplinary interpretive reports with accompanying plates on the geology, structure, geochronology, geophysics, hydrogeology, geochemistry, remote sensing (Landsat TM and ASTER), and SRTM and ASTER digital elevation models of Mauritania. The syntheses of these multidisciplinary data formed the basis for additional chapters containing interpretive reports on 12 different commodities and deposit types known to occur in Mauritania, accompanied by countrywide mineral resource potential maps of each commodity/deposit type. The commodities and deposit types represented include: (1) Ni, Cu, PGE, and Cr deposits hosted in ultramafic rocks; (2) orogenic, Carlin-like, and epithermal gold deposits; (3) polymetallic Pb-Zn-Cu vein deposits; (4) sediment-hosted Pb-Zn-Ag deposits of the SEDEX and Mississippi Valley-type; (5) sediment-hosted copper deposits; ( 6) volcanogenic massive sulfide deposits; (7) iron oxide copper-gold deposits; (8) uranium deposits; (9) Algoma-, Superior-, and oolitic-type iron deposits; (10) shoreline Ti-Zr placer deposits; (11) incompatible element deposits hosted in pegmatites, alkaline rocks, and carbonatites, and; (12) industrial mineral deposits. Additional chapters include the Mauritanian National Mineral Deposits Database are accompanied by an explanatory text and the Mauritania Minerals Project GIS that contains all of the interpretive layers created by USGS scientists. Raw data not in the public domain may be obtained from the Ministry of Petroleum, Energy, and Mines in Nouakchott, Mauritania.

Variability and genetics of spacer DNA sequences between the ribosomal-RNA genes of hexaploid wheat (Triticum aestivum).

PubMed

May, C E; Appels, R

1987-09-01

Using restriction enzyme digests of genomic DNA extracted from the leaves of 25 hexaploid wheat (Triticum aestivum L. em. Thell.) cultivars and their hybrids, restriction fragment length polymorphisms of the spacer DNA which separates the ribosomal-RNA genes have been examined. (From one to three thousand of these genes are borne on chromosomes 1B and 6B of hexaploid wheat). The data show that there are three distinct alleles of the 1B locus, designated Nor-B1a, Nor-B1b, and Nor-B1c, and at least five allelic variants of the 6B locus, designated Nor-B2a, Nor-B2b, Nor-B2c, Nor-B2d, and Nor-B2e. A further, previously reported allele on 6B has been named Nor-B2f. Chromosome 5D has only one allelic variant, Nor-D3. Whereas the major spacer variants of the 1B alleles apparently differ by the loss or gain of one or two of the 133 bp sub-repeat units within the spacer DNA, the 6B allelic variants show major differences in their compositions and lengths. This may be related to the greater number of rDNA repeat units at this locus. The practical implications of these differences and their application to wheat breeding are discussed.

Multi-centre audit of VMAT planning and pre-treatment verification.

PubMed

Jurado-Bruggeman, Diego; Hernández, Victor; Sáez, Jordi; Navarro, David; Pino, Francisco; Martínez, Tatiana; Alayrach, Maria-Elena; Ailleres, Norbert; Melero, Alejandro; Jornet, Núria

2017-08-01

We performed a multi-centre intercomparison of VMAT dose planning and pre-treatment verification. The aims were to analyse the dose plans in terms of dosimetric quality and deliverability, and to validate whether in-house pre-treatment verification results agreed with those of an external audit. The nine participating centres encompassed different machines, equipment, and methodologies. Two mock cases (prostate and head and neck) were planned using one and two arcs. A plan quality index was defined to compare the plans and different complexity indices were calculated to check their deliverability. We compared gamma index pass rates using the centre's equipment and methodology to those of an external audit (global 3D gamma, absolute dose differences, 10% of maximum dose threshold). Log-file analysis was performed to look for delivery errors. All centres fulfilled the dosimetric goals but plan quality and delivery complexity were heterogeneous and uncorrelated, depending on the manufacturer and the planner's methodology. Pre-treatment verifications results were within tolerance in all cases for gamma 3%-3mm evaluation. Nevertheless, differences between the external audit and in-house measurements arose due to different equipment or methodology, especially for 2%-2mm criteria with differences up to 20%. No correlation was found between complexity indices and verification results amongst centres. All plans fulfilled dosimetric constraints, but plan quality and complexity did not correlate and were strongly dependent on the planner and the vendor. In-house measurements cannot completely replace external audits for credentialing. Copyright © 2017 Elsevier B.V. All rights reserved.

Silicon millimetre-wave integrated-circuit (SIMMWIC) SPST switch

NASA Astrophysics Data System (ADS)

Stabile, P. J.; Rosen, A.

1984-10-01

The first silicon millimetre-wave integrated circuit (SIMMWIC) has been successfully fabricated. This circuit is a monolithic SPST switch with a 3 dB bandwidth of 20 percent and a minimum isolation of 21.6 dB across the band (centre frequency is 36.75 GHz). This monolithic circuit is a low-cost reproducible building block for all millimetre-wave control applications.

Rectangular Microstrip Antenna with Slot Embedded Geometry

NASA Astrophysics Data System (ADS)

Ambresh, P. A.; Hadalgi, P. M.; Hunagund, P. V.; Sujata, A. A.

2014-09-01

In this paper, a novel design that improves the performance of conventional rectangular microstrip antenna is discussed. Design adopts basic techniques such as probe feeding technique with rectangular inverted patch structure as superstrate, air filled dielectric medium as substrate and slot embedded patch. Prototype of the proposed antenna has been fabricated and various antenna performance parameters such as impedance bandwidth, return loss, radiation pattern and antenna gain are considered for Electromagnetic-study. The antennas are designed for the wireless application operating in the frequency range of 3.3 GHz to 3.6 GHz, and UK based fixed satellite service application (3 GHz to 4 GHz), and are named as single inverted patch conventional rectangular microstrip antenna (SIP-CRMSA) and slots embedded inverted patch rectangular microstrip antenna (SEIP-RMSA), respectively. Measurement outcomes for SEIP-RMSA1 and SEIP-RMSA2 showed the satisfactory performance with an achievable impedance bandwidth of 260 MHz (7 %) and 250 MHz (6.72 %), with return loss (RL) of -11.06 dB and -17.98 dB, achieved gain of 8.17 dB and 5.17 dB with 10% and 8% size reduction in comparison with the conventional patch antenna.

16 CFR 1102.44 - Applicability of sections 6(a) and (b) of the CPSA.

Code of Federal Regulations, 2011 CFR

2011-01-01

... PRODUCT SAFETY ACT REGULATIONS PUBLICLY AVAILABLE CONSUMER PRODUCT SAFETY INFORMATION DATABASE (Eff. Jan... publication in § 1102.10(d) in the Database. (b) Limitation on construction. Section 1102.44(a) shall not be...

16 CFR § 1102.44 - Applicability of sections 6(a) and (b) of the CPSA.

Code of Federal Regulations, 2013 CFR

2013-01-01

... CONSUMER PRODUCT SAFETY ACT REGULATIONS PUBLICLY AVAILABLE CONSUMER PRODUCT SAFETY INFORMATION DATABASE... § 1102.10(d) in the Database. (b) Limitation on construction. Section 1102.44(a) shall not be construed...

48 CFR 314.103 - Policy.

Code of Federal Regulations, 2010 CFR

2010-10-01

... CONTRACT TYPES SEALED BIDDING Use of Sealed Bidding 314.103 Policy. EIT products and services, including EIT deliverables such as electronic documents and reports, acquired using sealed-bid procedures shall... determinations for EIT products and services that do not meet some or all of the applicable Section 508...

Teachers' Views of Inclusion: "I'd Rather Pump Gas."

ERIC Educational Resources Information Center

Vaughn, Sharon; And Others

The issue of inclusion has been at the forefront of attention in education, and has been widely discussed and debated. Since teachers will be the primary service deliverers of whatever inclusion practices are adopted, this study was conducted in an attempt better to understand teachers' understanding and perceptions of inclusion. Focus group…

Characterization of unpaved road condition through the use of remote sensing project - phase II, deliverable 8-D: final report.

DOT National Transportation Integrated Search

2016-03-07

Building on the success of developing a UAV based unpaved road assessment system in Phase I, the project team was awarded a Phase II project by the USDOT to focus on outreach and implementation. The project team added Valerie Lefler of Integrated Glo...

A monolithic RF transceiver for DC-OFDM UWB

NASA Astrophysics Data System (ADS)

Yunfeng, Chen; Wei, Li; Haipeng, Fu; Ting, Gao; Danfeng, Chen; Feng, Zhou; Deyun, Cai; Dan, Li; Yangyang, Niu; Hanchao, Zhou; Ning, Zhu; Ning, Li; Junyan, Ren

2012-02-01

This paper presents a first monolithic RF transceiver for DC-OFDM UWB applications. The proposed direct-conversion transceiver integrates all the building blocks including two receiver (Rx) cores, two transmitter (Tx) cores and a dual-carrier frequency synthesizer (DC-FS) as well as a 3-wire serial peripheral interface (SPI) to set the operating status of the transceiver. The ESD-protected chip is fabricated by a TSMC 0.13-μm RF CMOS process with a die size of 4.5 × 3.6 mm2. The measurement results show that the wideband Rx achieves an NF of 5-6.2 dB, a max gain of 76-84 dB with 64-dB variable gain, an in-/out-of-band IIP3 of -6/+4 dBm and an input loss S11 of < -10 in all bands. The Tx achieves an LOLRR/IMGRR of -34/-33 dBc, a typical OIP3 of +6 dBm and a maximum output power of -5 dBm. The DC-FS outputs two separate carriers simultaneously with an inter-band hopping time of < 1.2 ns. The full chip consumes a maximum current of 420 mA under a 1.2-V supply.

Bend-insensitive single-mode photonic crystal fiber with ultralarge effective area for dual applications

NASA Astrophysics Data System (ADS)

Islam, Md. Asiful; Alam, M. Shah

2013-05-01

A novel photonic crystal fiber (PCF) having circular arrangement of cladding air holes has been designed and numerically optimized to obtain a bend insensitive single mode fiber with large mode area for both wavelength division multiplexing (WDM) communication and fiber-to-the-home (FTTH) application. The bending loss of the proposed bent PCF lies in the range of 10-3 to 10-4 dB/turn or lower over 1300 to 1700 nm, and 2 × 10-4 dB/turn at the wavelength of 1550 nm for a 30-mm bend radius with a higher order mode (HOM) cut-off frequency below 1200 nm for WDM application. When the whole structure of the PCF is scaled down, a bending loss of 6.78×10-4 dB/turn at 1550 nm for a 4-mm bend radius is obtained, and the loss remains in the order of 10-4 dB/turn over the same range of wavelength with an HOM cut-off frequency below 700 nm, and makes the fiber useful for FTTH applications. Furthermore, this structure is also optimized to show a splice loss near zero for fusion-splicing to a conventional single-mode fiber (SMF).

42 CFR 410.160 - Part B annual deductible.

Code of Federal Regulations, 2012 CFR

2012-10-01

... hepatitis b vaccines and their administration. (3) Federally qualified health center services. (4) ASC... services as described in § 410.34 (c) and (d). (6) Screening pelvic examinations as described in § 410.56... through the national coverage determination (NCD) process. (c) Application of the Part B annual deductible...

42 CFR 410.160 - Part B annual deductible.

Code of Federal Regulations, 2011 CFR

2011-10-01

... hepatitis b vaccines and their administration. (3) Federally qualified health center services. (4) ASC... services as described in § 410.34 (c) and (d). (6) Screening pelvic examinations as described in § 410.56... through the national coverage determination (NCD) process. (c) Application of the Part B annual deductible...

20 CFR 638.812 - State and local taxation of Job Corps deliverers.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false State and local taxation of Job Corps deliverers. 638.812 Section 638.812 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF... § 638.812 State and local taxation of Job Corps deliverers. The Act provides that transactions conducted...

20 CFR 638.812 - State and local taxation of Job Corps deliverers.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 20 Employees' Benefits 3 2011-04-01 2011-04-01 false State and local taxation of Job Corps deliverers. 638.812 Section 638.812 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF... § 638.812 State and local taxation of Job Corps deliverers. The Act provides that transactions conducted...

Photothermal Deoxygenation of Graphene Oxide to Graphitic Carbon for Distributed Ignition and Patterning Applications (Preprint)

DTIC Science & Technology

2009-04-13

Brodie, B. Ann Chim. Phys. 1855, 45, 351 6. Dikin , D.; Stankovich, S.; Zimney, E. J.; Piner, R. D.; Dommett, H. B.; Evmenenko, G.; Nguyen, S. T...Stankovich, S.; Dikin , D. A.; Piner, R. D.; Kohlhaas, K. A.; Kleinhammes, A.; Jia, Y.; Wu, Y.; Nguyen, S. T.; Ruoff, R. S. Carbon 2007, 45(7), 1558...Gomez-Navarro, C.; Weitz, R. T.; Bittner, A. M.; Scolari, M.; Mews, A.; Burghrd. M.; Kern, K. Nano Lett. 2006, 7, 3499 16. Stankovich, S.; Dikin , D

Application of fuzzy logic-neural network based reinforcement learning to proximity and docking operations: Attitude control results

NASA Technical Reports Server (NTRS)

Jani, Yashvant

1992-01-01

As part of the RICIS activity, the reinforcement learning techniques developed at Ames Research Center are being applied to proximity and docking operations using the Shuttle and Solar Max satellite simulation. This activity is carried out in the software technology laboratory utilizing the Orbital Operations Simulator (OOS). This report is deliverable D2 Altitude Control Results and provides the status of the project after four months of activities and outlines the future plans. In section 2 we describe the Fuzzy-Learner system for the attitude control functions. In section 3, we provide the description of test cases and results in a chronological order. In section 4, we have summarized our results and conclusions. Our future plans and recommendations are provided in section 5.

32 CFR Attachment 3 to Part 855 - Landing Permit Application Instructions

Code of Federal Regulations, 2011 CFR

2011-07-01

.... A3.1.12. Block 9b, Signature. The form must be signed in blue ink so that hand scribed, original... lights, a transponder, or IFR capabilities. A3.2.13. Block 6a. Self-explanatory. A3.2.14. Block 6b. If... should contain a daytime telephone number. A3.2.16. Block 6d. The form must be signed in blue ink so that...

32 CFR Attachment 3 to Part 855 - Landing Permit Application Instructions

Code of Federal Regulations, 2012 CFR

2012-07-01

.... A3.1.12. Block 9b, Signature. The form must be signed in blue ink so that hand scribed, original... lights, a transponder, or IFR capabilities. A3.2.13. Block 6a. Self-explanatory. A3.2.14. Block 6b. If... should contain a daytime telephone number. A3.2.16. Block 6d. The form must be signed in blue ink so that...

32 CFR Attachment 3 to Part 855 - Landing Permit Application Instructions

Code of Federal Regulations, 2014 CFR

2014-07-01

.... A3.1.12. Block 9b, Signature. The form must be signed in blue ink so that hand scribed, original... lights, a transponder, or IFR capabilities. A3.2.13. Block 6a. Self-explanatory. A3.2.14. Block 6b. If... should contain a daytime telephone number. A3.2.16. Block 6d. The form must be signed in blue ink so that...

32 CFR Attachment 3 to Part 855 - Landing Permit Application Instructions

Code of Federal Regulations, 2013 CFR

2013-07-01

.... A3.1.12. Block 9b, Signature. The form must be signed in blue ink so that hand scribed, original... lights, a transponder, or IFR capabilities. A3.2.13. Block 6a. Self-explanatory. A3.2.14. Block 6b. If... should contain a daytime telephone number. A3.2.16. Block 6d. The form must be signed in blue ink so that...

77 FR 65864 - Receipt of an Application for Incidental Take Permit (16230)

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-31

... by dividing estuarine waters into 6 management units (i.e., A, B, C, D1, D2, E). Each of the... into two areas, D1 and D2, to allow the NCDMF to effectively address areas of high sea turtle abundance.... Management Unit D1 includes Southern Core Sound, Back Sound and North River. Management Unit D2 encompasses...

Modular Towed Acoustic Sonar Array

DTIC Science & Technology

2014-02-04

Dkt . No...d 11 5 11 0c 11 0d 11 5 14 0 16 0’ 1 60 ’’ 12 0 14 0 12 0 14 0 13 0 14 0 12 0 13 0 12 0 12 0 13 0 14 0 16 0 10 0 d 2 d 3 Dkt . No. 102060 Application...of Non-Acoustic Sensors in Second Sensor Array Dkt . No. 102060 Application No. ?? REPLACEMENT SHEET? /3 1st DRAFT 3 F IG . 3 11 5 16 4 16 8 16 2 16 6 11 5 1 50 11 0b 18 0 17 0 16 6a 16 4a 18 0 10 0 11 0a 15 0

Project Turnover Deliverables for the SY Farm Enraf Annulus Leak Detectors

DOE Office of Scientific and Technical Information (OSTI.GOV)

SCAIEF, C.C.

2000-09-19

This document identifies the deliverables that ensure the end user of the SY Farm Enraf Annulus Leak Detectors (ALD) has all the documentation and training required for operating and maintaining the new system. All deliverable items checked on the Acceptance For Beneficial Use (ABU) form have been completed and are available to the end user. This document was written as required by HNF-IP-0842, Volume IV section 3.12 Acceptance of Structures, Systems, and Components for Beneficial Use. This document applies to the deliverable documentation required to operate and maintain the SY Farm Enraf ALD System. Appendix A provides a copy ofmore » the ABU form as listed in the appendix of TWR-4092, Engineering Task Plan for the New SY Farm Annulus Leak Detectors. This document attests that all required deliverable items checked on the ABU have been completed and are available to the end user.« less

Self-test web-based pure-tone audiometry: validity evaluation and measurement error analysis.

PubMed

Masalski, Marcin; Kręcicki, Tomasz

2013-04-12

Potential methods of application of self-administered Web-based pure-tone audiometry conducted at home on a PC with a sound card and ordinary headphones depend on the value of measurement error in such tests. The aim of this research was to determine the measurement error of the hearing threshold determined in the way described above and to identify and analyze factors influencing its value. The evaluation of the hearing threshold was made in three series: (1) tests on a clinical audiometer, (2) self-tests done on a specially calibrated computer under the supervision of an audiologist, and (3) self-tests conducted at home. The research was carried out on the group of 51 participants selected from patients of an audiology outpatient clinic. From the group of 51 patients examined in the first two series, the third series was self-administered at home by 37 subjects (73%). The average difference between the value of the hearing threshold determined in series 1 and in series 2 was -1.54dB with standard deviation of 7.88dB and a Pearson correlation coefficient of .90. Between the first and third series, these values were -1.35dB±10.66dB and .84, respectively. In series 3, the standard deviation was most influenced by the error connected with the procedure of hearing threshold identification (6.64dB), calibration error (6.19dB), and additionally at the frequency of 250Hz by frequency nonlinearity error (7.28dB). The obtained results confirm the possibility of applying Web-based pure-tone audiometry in screening tests. In the future, modifications of the method leading to the decrease in measurement error can broaden the scope of Web-based pure-tone audiometry application.

Deliverability and efficacy of R-CHOP chemotherapy in very elderly patients with diffuse large B-cell lymphoma: an Australian retrospective analysis.

PubMed

Millar, A; Ellis, M; Mollee, P; Cochrane, T; Fletcher, J; Caudron, A; Webster, B; Trotman, J

2015-11-01

Elderly patients with diffuse large B-cell lymphoma (DLBCL) have an inferior prognosis, due in part to advanced age and pre-existing comorbidities, with reduced tolerability and deliverability of standard R-CHOP chemotherapy. To examine the deliverability, toxicity and efficacy of R-CHOP and the prevalence of the germinal and non-germinal phenotype DLBCL in an elderly Australian cohort. This retrospective analysis included patients ≥75 years diagnosed with DLBCL. Comprehensive chemotherapy and toxicity data were collected for patients treated with R-CHOP. Baseline demographics and chemotherapy characteristics were compared with progression-free (PFS) and overall survival (OS). Immunohistochemical staining identified the prevalence of the non-germinal centre (non-GCB) phenotype. Of the 111 patients, 92 (83%) commenced R-CHOP with 26/92 (28%) receiving ≤4 cycles. Median average relative dose (ARD) was 0.80 (0.07-1.17). Median average relative dose intensity (ARDI) was 0.89 (0.33-1.18). Serious adverse events occurred in 77% of patients with ≥Gd3 adverse events in 74%. Overall response rate was 85%. Two-year PFS was 63% and OS 74%. ARD and performance status ≥2 were significant prognostic factors for PFS and OS but not ARDI. Non-GCB-phenotype was identified in 44/72 (61%) of patients with immunohistochemical data. Despite high response rates and respectable survival estimates, the absence of standard therapy in 17% of patients, and dose reductions and serious toxicity of R-CHOP in this Australian cohort highlights the need for the development of less toxic yet efficacious treatments for very elderly patients with DLBCL. The high prevalence of the non-GCB phenotype highlights the potential value of targeted biological therapy for this demographic. © 2015 Royal Australasian College of Physicians.

A Three Dimensional Electronic Retina Architecture.

DTIC Science & Technology

1987-12-01

not guarantee that a biological entity is in fact the best design because of the unique constraining factors of a biological organism and the associated...4. PERFORMING ORGANIZATION REPORT NUMBER(S) 5. MONITORING ORGANIZATION REPORT NUMBER(S) AFIT/GCS/ENG/87D-23 6a. NAME OF PERFORMING ORGANIZATION 6b...OFFICE SYMBOL 7a. NAME OF MONITORING ORGANIZATION (If applicable) School of Engineering AFIT/ENG 6c. ADDRESS (City, State, and ZIP Code) 7b. ADDRESS

The Challenge of Connecting the Dots in the B.R.A.I.N

PubMed Central

Devor, Anna; Bandettini, Peter A.; Boas, David A.; Bower, James M.; Buxton, Richard B.; Cohen, Lawrence B.; Dale, Anders M.; Einevoll, Gaute T.; Fox, Peter T.; Franceschini, Maria Angela; Friston, Karl J.; Fujimoto, James G.; Geyer, Marc A.; Greenberg, Joel H.; Halgren, Eric; Hämäläinen, Matti S.; Helmchen, Fritjof; Hyman, Bradley T.; Jasanoff, Alan; Jernigan, Terry L.; Judd, Lewis L.; Kim, Seong-Gi; Kleinfeld, David; Kopell, Nancy J.; Kutas, Marta; Kwong, Kenneth K.; Larkum, Matthew E.; Lo, Eng H.; Magistretti, Pierre J.; Mandeville, Joseph B.; Masliah, Eliezer; Mitra, Partha P.; Mobley, William C.; Moskowitz, Michael A.; Nimmerjahn, Axel; Reynolds, John H.; Rosen, Bruce R.; Salzberg, Brian M.; Schaffer, Chris B.; Silva, Gabriel A.; So, Peter T. C.; Spitzer, Nicholas C.; Tootell, Roger B.; Van Essen, David C.; Vanduffel, Wim; Vinogradov, Sergei A.; Wald, Larry L.; Wang, Lihong V.; Weber, Bruno; Yodh, Arjun G.

2013-01-01

The Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative has focused scientific attention on the necessary tools to understand the human brain and mind. Here, we outline our collective vision for what we can achieve within a decade with properly targeted efforts, and discuss likely technological deliverables and neuroscience progress. PMID:24139032

Quality of Service for Real-Time Applications Over Next Generation Data Networks

NASA Technical Reports Server (NTRS)

Atiquzzaman, Mohammed; Jain, Raj

2001-01-01

This project, which started on January 1, 2000, was funded by the NASA Glenn Research Center for duration of one year. The deliverables of the project included the following tasks: (1) Study of QoS mapping between the edge and core networks envisioned in the Next Generation networks will provide us with the QoS guarantees that can be obtained from next generation networks; (2) Buffer management techniques to provide strict guarantees to real-time end-to-end applications through preferential treatment to packets belonging to real-time applications. In particular, use of ECN to help reduce the loss on high bandwidth-delay product satellite networks needs to be studied; (3) Effect of Prioritized Packet Discard to increase goodput of the network and reduce the buffering requirements in the ATM switches; (4) Provision of new IP circuit emulation services over Satellite IP backbones using MPLS will be studied; and (5) Determine the architecture and requirements for internetworking ATN and the Next Generation Internet for real-time applications. The project has been completed on time. All the objectives and deliverables of the project have been completed. Research results obtained from this project have been published in a number of papers in journals, conferences, and technical reports, included in this document.

Select Generic Dry-Storage Pilot Plant Design for Safeguards and Security by Design (SSBD) per Used Fuel Campaign

DOE Office of Scientific and Technical Information (OSTI.GOV)

Demuth, Scott Francis; Sprinkle, James K.

As preparation to the year-end deliverable (Provide SSBD Best Practices for Generic Dry-Storage Pilot Scale Plant) for the Work Package (FT-15LA040501–Safeguards and Security by Design for Extended Dry Storage), the initial step was to select a generic dry-storage pilot plant design for SSBD. To be consistent with other DOE-NE Fuel Cycle Research and Development (FCR&D) activities, the Used Fuel Campaign was engaged for the selection of a design for this deliverable. For the work Package FT-15LA040501–“Safeguards and Security by Design for Extended Dry Storage”, SSBD will be initiated for the Generic Dry-Storage Pilot Scale Plant described by the layout ofmore » Reference 2. SSBD will consider aspects of the design that are impacted by domestic material control and accounting (MC&A), domestic security, and international safeguards.« less

Synthesis of geological, structural, and geochronologic data (phase V, deliverable 53): Chapter A in Second projet de renforcement institutionnel du secteur minier de la République Islamique de Mauritanie (PRISM-II)

USGS Publications Warehouse

Bradley, Dwight C.; O'Sullivan, Paul; Cosca, Michael A.; Motts, Holly; Horton, John D.; Taylor, Cliff D.; Beaudoin, Georges; Lee, Gregory K.; Ramezani, Jahan; Bradley, Daniel N.; Jones, James V.; Bowring, Samuel

2015-01-01

This report is a companion to the new Geologic Map of Mauritania (Bradley and others, 2015; referred to herein as “Deliverable 51”) and the new Structural Geologic Map of Mauritania (Bradley and others, 2015a; referred to herein as “Deliverable 52”). Section 1 contains explanatory information for these two digital maps. Section 2 covers the analytical methods used in obtaining new U-Pb ages from 9 igneous rock samples, new detrital zircon ages from 40 sedimentary or metasedimentary rock samples, and new 40Ar/39Ar ages from 12 samples of metamorphic rocks and veins. Sections 3 through 6 present the new geochronological results, organized by region. In Section 7, we discuss implications of the new ages for the regional geology and discuss problematic results. Finally, in Section 8, we summarize the geology and tectonic evolution of Mauritania in narrative form, drawing on new and published information, in the context of global tectonics. The report is being released in both English and French. In both versions, we use the French-language names for formal stratigraphic units.

A Comparison of the Behavior of Functional/Basis Set Combinations for Hydrogen-Bonding in the Water Dimer with Emphasis on Basis Set Superposition Error

PubMed Central

Plumley, Joshua A.; Dannenberg, J. J.

2011-01-01

We evaluate the performance of nine functionals (B3LYP, M05, M05-2X, M06, M06-2X, B2PLYP, B2PLYPD, X3LYP, B97D and MPWB1K) in combination with 16 basis sets ranging in complexity from 6-31G(d) to aug-cc-pV5Z for the calculation of the H-bonded water dimer with the goal of defining which combinations of functionals and basis sets provide a combination of economy and accuracy for H-bonded systems. We have compared the results to the best non-DFT molecular orbital calculations and to experimental results. Several of the smaller basis sets lead to qualitatively incorrect geometries when optimized on a normal potential energy surface (PES). This problem disappears when the optimization is performed on a counterpoise corrected PES. The calculated ΔE's with the largest basis sets vary from -4.42 (B97D) to -5.19 (B2PLYPD) kcal/mol for the different functionals. Small basis sets generally predict stronger interactions than the large ones. We found that, due to error compensation, the smaller basis sets gave the best results (in comparison to experimental and high level non-DFT MO calculations) when combined with a functional that predicts a weak interaction with the largest basis set. Since many applications are complex systems and require economical calculations, we suggest the following functional/basis set combinations in order of increasing complexity and cost: 1) D95(d,p) with B3LYP, B97D, M06 or MPWB1k; 2) 6-311G(d,p) with B3LYP; 3) D95++(d,p) with B3LYP, B97D or MPWB1K; 4)6-311++G(d,p) with B3LYP or B97D; and 5) aug-cc-pVDZ with M05-2X, M06-2X or X3LYP. PMID:21328398

A comparison of the behavior of functional/basis set combinations for hydrogen-bonding in the water dimer with emphasis on basis set superposition error.

PubMed

Plumley, Joshua A; Dannenberg, J J

2011-06-01

We evaluate the performance of ten functionals (B3LYP, M05, M05-2X, M06, M06-2X, B2PLYP, B2PLYPD, X3LYP, B97D, and MPWB1K) in combination with 16 basis sets ranging in complexity from 6-31G(d) to aug-cc-pV5Z for the calculation of the H-bonded water dimer with the goal of defining which combinations of functionals and basis sets provide a combination of economy and accuracy for H-bonded systems. We have compared the results to the best non-density functional theory (non-DFT) molecular orbital (MO) calculations and to experimental results. Several of the smaller basis sets lead to qualitatively incorrect geometries when optimized on a normal potential energy surface (PES). This problem disappears when the optimization is performed on a counterpoise (CP) corrected PES. The calculated interaction energies (ΔEs) with the largest basis sets vary from -4.42 (B97D) to -5.19 (B2PLYPD) kcal/mol for the different functionals. Small basis sets generally predict stronger interactions than the large ones. We found that, because of error compensation, the smaller basis sets gave the best results (in comparison to experimental and high-level non-DFT MO calculations) when combined with a functional that predicts a weak interaction with the largest basis set. As many applications are complex systems and require economical calculations, we suggest the following functional/basis set combinations in order of increasing complexity and cost: (1) D95(d,p) with B3LYP, B97D, M06, or MPWB1k; (2) 6-311G(d,p) with B3LYP; (3) D95++(d,p) with B3LYP, B97D, or MPWB1K; (4) 6-311++G(d,p) with B3LYP or B97D; and (5) aug-cc-pVDZ with M05-2X, M06-2X, or X3LYP. Copyright © 2011 Wiley Periodicals, Inc.

Bilogy Machine Initiative: Developing Innovative Novel Methods to Improve Neuro-rehabilitation for Amputees and Treatment for Patients at Remote Sites with Acute Brain Injury

DTIC Science & Technology

2010-09-01

service to support the creation of both normative and pathological neuroinformatics databases. Project 3 Deliverable: The aim of this project is to...Gainesville, FL, 2010. D. Hammond, P. Vandergheynst, R. Gribonval, “ Wavelets on Graphs via Spectral Graph Theory,” Applied Computational and...the Phantom Experiments,” International Conference on Electrical Bioimpedance, April 4-8-, Gainesville, FL, 2010. 21 D. Hammond, “ Wavelets on

The Use of a Higher Order Kinematic Relationship on the Analysis of Cylindrical Composite Panels

DTIC Science & Technology

1991-12-01

form: exNl All A 12 A 16 B11 B12 B16 D nl D12 D16 E11 E12 E16 F11 F12 F16 COyI A12 A22 A6 B12 B22 B 1 D 2 D22 D26 E12 E2 2 E16 F1 2 F22 F26 0 A16 A 26...2 + 2E,,)kw,, ,., " kErWly + (kE11 + B 1 1)4f.,. + 2(kE 6 B16 )*.,x,, + (kE6 6 + B 616 ) *X,yy + (kE 1 6 + B 1 6 ) *y,, + [k (E1 2 + E6 6 ) " B12...B1 6 ) *x, y " (kE1 6 + B1 6 ) 1Y~ + (kE31 2 + B12) p,y, + -R-- 1 O 2 - B16 o, x + 12 W- 16W y- kF12 W, y - Wk16 + D6 x x-a W k 12 + D1 2)4r,y, 0 auo

48 CFR 31.205-6 - Compensation for personal services.

Code of Federal Regulations, 2013 CFR

2013-10-01

... following: (A) To all executive agencies, other than DoD, NASA and the Coast Guard, for contracts awarded before, on, or after December 31, 2011; (B) To DoD, NASA, and the Coast Guard for contracts awarded... limit. (i) Applicability. This paragraph (p)(2) applies to DoD, NASA, and the Coast Guard for contracts...

FT-IR spectroscopic analyses of 2-(2-furanylmethylene) propanedinitrile

NASA Astrophysics Data System (ADS)

Soliman, H. S.; Eid, Kh. M.; Ali, H. A. M.; El-Mansy, M. A. M.; Atef, S. M.

2013-03-01

In the present work, a computational study for the optimized molecular structural parameters, thermo-chemical parameters, total dipole moment, HOMO-LUMO energy gap and a combined experimental and computational study for FT-IR spectra for 2-(2-furanylmethylene) propanedinitrile have been investigated using B3LYP utilizing 6-31G and 6-311G basis set. Our calculated results showed that the investigated compound possesses a dipole moment of 7.5 D and HOMO-LUMO energy gap of 3.92 eV using B3LYP/6-311G which indicates that our investigated compound is highly applicable for photovoltaic solar cell applications.

42 CFR 410.160 - Part B annual deductible.

Code of Federal Regulations, 2013 CFR

2013-10-01

... hepatitis b vaccines and their administration. (3) Federally qualified health center services. (4) ASC... services as described in § 410.34 (c) and (d). (6) Screening pelvic examinations as described in § 410.56... services identified for coverage through the national coverage determination (NCD) process. (c) Application...

42 CFR 410.160 - Part B annual deductible.

Code of Federal Regulations, 2014 CFR

2014-10-01

... hepatitis b vaccines and their administration. (3) Federally qualified health center services. (4) ASC... services as described in § 410.34 (c) and (d). (6) Screening pelvic examinations as described in § 410.56... services identified for coverage through the national coverage determination (NCD) process. (c) Application...

Novel power MOSFET-based expander for high frequency ultrasound systems.

PubMed

Choi, Hojong; Shung, K Kirk

2014-01-01

The function of an expander is to obstruct the noise signal transmitted by the pulser so that it does not pass into the transducer or receive electronics, where it can produce undesirable ring-down in an ultrasound imaging application. The most common type is a diode-based expander, which is essentially a simple diode-pair, is widely used in pulse-echo measurements and imaging applications because of its simple architecture. However, diode-based expanders may degrade the performance of ultrasonic transducers and electronic components on the receiving and transmitting sides of the ultrasound systems, respectively. Since they are non-linear devices, they cause excessive signal attenuation and noise at higher frequencies and voltages. In this paper, a new type of expander that utilizes power MOSFET components, which we call a power MOSFET-based expander, is introduced and evaluated for use in high frequency ultrasound imaging systems. The performance of a power MOSFET-based expander was evaluated relative to a diode-based expander by comparing the noise figure (NF), insertion loss (IL), total harmonic distortion (THD), response time (RT), electrical impedance (EI) and dynamic power consumption (DPC). The results showed that the power MOSFET-based expander provided better NF (0.76 dB), IL (-0.3 dB) and THD (-62.9 dB), and faster RT (82 ns) than did the diode-based expander (NF (2.6 dB), IL (-1.4 dB), THD (-56.0 dB) and RT (119 ns)) at 70 MHz. The -6 dB bandwidth and the peak-to-peak voltage of the echo signal received by the transducer using the power MOSFET-based expander improved by 17.4% and 240% compared to the diode-based expander, respectively. The new power MOSFET-based expander was shown to yield lower NF, IL and THD, faster RT and lower ring down than the diode-based expander at the expense of higher dynamic power consumption. Copyright © 2013 Elsevier B.V. All rights reserved.

A 14-bit 40-MHz analog front end for CCD application

NASA Astrophysics Data System (ADS)

Jingyu, Wang; Zhangming, Zhu; Shubin, Liu

2016-06-01

A 14-bit, 40-MHz analog front end (AFE) for CCD scanners is analyzed and designed. The proposed system incorporates a digitally controlled wideband variable gain amplifier (VGA) with nearly 42 dB gain range, a correlated double sampler (CDS) with programmable gain functionality, a 14-bit analog-to-digital converter and a programmable timing core. To achieve the maximum dynamic range, the VGA proposed here can linearly amplify the input signal in a gain range from -1.08 to 41.06 dB in 6.02 dB step with a constant bandwidth. A novel CDS takes image information out of noise, and further amplifies the signal accurately in a gain range from 0 to 18 dB in 0.035 dB step. A 14-bit ADC is adopted to quantify the analog signal with optimization in power and linearity. An internal timing core can provide flexible timing for CCD arrays, CDS and ADC. The proposed AFE was fabricated in SMIC 0.18 μm CMOS process. The whole circuit occupied an active area of 2.8 × 4.8 mm2 and consumed 360 mW. When the frequency of input signal is 6.069 MHz, and the sampling frequency is 40 MHz, the signal to noise and distortion (SNDR) is 70.3 dB, the effective number of bits is 11.39 bit. Project supported by the National Natural Science Foundation of China (Nos. 61234002, 61322405, 61306044, 61376033), the National High-Tech Program of China (No. 2013AA014103), and the Opening Project of Science and Technology on Reliability Physics and Application Technology of Electronic Component Laboratory (No. ZHD201302).

78 FR 69155 - Altegris Advisors, L.L.C., et al.; Notice of Application

Federal Register 2010, 2011, 2012, 2013, 2014

2013-11-18

... Advisors, L.L.C., et al.; Notice of Application November 12, 2013. AGENCY: Securities and Exchange..., under sections 6(c) and 17(b) of the Act for an exemption from sections 17(a)(1) and (2) of the Act, and under section 6(c) of the Act for an exemption from rule 12d1- 2(a) under the Act. Summary of...

Collaborative Undergraduate HBCU Student Summer Prostate Cancer Training Program

DTIC Science & Technology

2012-09-01

University Dr. Harry S. Clarke Hormone Supplementation and Risk for Prostate Cancer 16 Task 1 Deliverables: Twelve Student Fellows were...Addiction & Alcohol Dr. Corrigan Smothers July 17 H - Aspirin & NSAIDS Dr. Halushka July 20 C – Herbals & Cancer...M) Powerpoint Presentation Workshop July 20 (M) Alternative Careers in Science (12-1pm) Dr. Craig Plante, PhD July 21 (C) Herbals & Cancer

30 CFR 250.115 - How do I determine well producibility?

Code of Federal Regulations, 2010 CFR

2010-07-01

... well is an oil well, you must conduct a production test that lasts at least 2 hours after flow stabilizes. (d) If the well is a gas well, you must conduct a deliverability test that lasts at least 2 hours... 30 Mineral Resources 2 2010-07-01 2010-07-01 false How do I determine well producibility? 250.115...

The National Shipbuilding Research Program. Application of Industrial Engineering Techniques to Reduce Workers’ Compensation and Environmental Costs - Deliverable F

DTIC Science & Technology

1999-10-01

body size, pre-existing medical conditions, medication and sedentary lifestyle . Team members learned from professional speakers and other training...for the retired military employee who may lead a more " sedentary lifestyle ". Smoking and overeating are also negative factors that increase the

75 FR 71101 - Monroe Gas Storage Company, LLC; Notice of Application

Federal Register 2010, 2011, 2012, 2013, 2014

2010-11-22

... to comment only on the environmental review of this project should submit an original and two copies... Monroe to make changes to the certificated design of the Monroe Gas Storage Project. Specifically... high-deliverability working gas storage capacity, with about 4.46 Bcf of base gas. Nor is any change...

75 FR 8902 - Funding Opportunity Title: Crop Insurance Education in Targeted States (Targeted States Program)

Federal Register 2010, 2011, 2012, 2013, 2014

2010-02-26

... DEPARTMENT OF AGRICULTURE Federal Crop Insurance Corporation Funding Opportunity Title: Crop... partners working on the project, their titles, and how they will be contributing to the deliverables listed... Director has issued an award under the terms of this request for applications; (2) Title of project; (3...

Conservation paleobiology: Leveraging knowledge of the past to inform conservation and restoration

USGS Publications Warehouse

Dietl, Gregory P.; Kidwell, Susan M.; Brenner, Mark; Burney, David A.; Flessa, Karl W.; Jackson, Stephen T.; Koch, Paul L.

2015-01-01

Humans now play a major role in altering Earth and its biota. Finding ways to ameliorate human impacts on biodiversity and to sustain and restore the ecosystem services on which we depend is a grand scientific and societal challenge. Conservation paleobiology is an emerging discipline that uses geohistorical data to meet these challenges by developing and testing models of how biota respond to environmental stressors. Here we (a) describe how the discipline has already provided insights about biotic responses to key environmental stressors, (b) outline research aimed at disentangling the effects of multiple stressors, (c) provide examples of deliverables for managers and policy makers, and (d) identify methodological advances in geohistorical analysis that will foster the next major breakthroughs in conservation outcomes. We highlight cases for which exclusive reliance on observations of living biota may lead researchers to erroneous conclusions about the nature and magnitude of biotic change, vulnerability, and resilience.

Conservation Paleobiology: Leveraging Knowledge of the Past to Inform Conservation and Restoration

NASA Astrophysics Data System (ADS)

Dietl, Gregory P.; Kidwell, Susan M.; Brenner, Mark; Burney, David A.; Flessa, Karl W.; Jackson, Stephen T.; Koch, Paul L.

2015-05-01

Humans now play a major role in altering Earth and its biota. Finding ways to ameliorate human impacts on biodiversity and to sustain and restore the ecosystem services on which we depend is a grand scientific and societal challenge. Conservation paleobiology is an emerging discipline that uses geohistorical data to meet these challenges by developing and testing models of how biota respond to environmental stressors. Here we (a) describe how the discipline has already provided insights about biotic responses to key environmental stressors, (b) outline research aimed at disentangling the effects of multiple stressors, (c) provide examples of deliverables for managers and policy makers, and (d) identify methodological advances in geohistorical analysis that will foster the next major breakthroughs in conservation outcomes. We highlight cases for which exclusive reliance on observations of living biota may lead researchers to erroneous conclusions about the nature and magnitude of biotic change, vulnerability, and resilience.

Crystal structure and texture changes during thermal cycling of TATB

DOE Office of Scientific and Technical Information (OSTI.GOV)

Vogel, Sven C.; Yeager, John David

2015-02-20

Goals: Understand crystal structure and micro-structure changes during thermal cycling, understand reasons for ratcheting of TATB during thermal cycling, and Support of B61 LEP. Deliverables achieved: Completed in situ thermal cycling of loose powder and pressed pellet TATB on HIPPO, Quantified preferred orientation of pressed pellet, and quantified relative change of each of the six lattic parameters.

Landsat maps (phase V, deliverable 60), ASTER maps (phase V, deliverable 62), ASTER_DEM maps (phase V, deliverable 63), and spectral remote sensing in support of PRISM-II mineral resource assessment project, Islamic Republic of Mauritania (phase V, deliverables 61 and 64): Chapter E in Second projet de renforcement institutionnel du secteur minier de la République Islamique de Mauritanie (PRISM-II)

USGS Publications Warehouse

Rockwell, Barnaby W.; Knepper, Daniel H.; Horton, John D.

2015-01-01

The image products derived from Landsat TM and ASTER data enable the delineation of mineral groups across wide areas based on color response. Guides are provided that allow users to interpret these colors as to mineral group occurrence over lithologic units and known deposits. This information can be extrapolated to other geologically permissive tracts for various deposit types in the search for similar mineralogic responses that may be indicative of concealed deposits.

Contractors Road Heavy Equipment Area SWMU 055 Corrective Measures Implementation Progress Report Kennedy Space Center, Florida

NASA Technical Reports Server (NTRS)

Johnson, Jill W. (Compiler)

2015-01-01

This Corrective Measures Implementation (CMI) Progress Report documents: (i) activities conducted as part of supplemental assessment activities completed from June 2009 through November 2014; (ii) Engineering Evaluation (EE) Advanced Data Packages (ADPs); and (iii) recommendations for future activities related to corrective measures at the Site. Applicable meeting minutes are provided as Appendix A. The following EE ADPs for CRHE are included with this CMI Progress Report: center dot Supplemental Site Characterization ADP (Step 1 EE) (Appendix B) center dot Site Characterization ADP (Step 1 EE) for Hot Spot 1 (HS1) (Appendix C) center dot Remedial Alternatives Evaluation (Step 2 EE) ADP for HS1 (Appendix D) center dot Interim Measures Work Plan (Step 3 EE) ADP for HS1 (Appendix E) center dot Site Characterization ADP (Step 1 EE) ADP for Hot Spot 2 (HS2), High Concentration Plume (HCP), and Low Concentration Plume (LCP) (Appendix F) A summary of direct-push technology (DPT) and groundwater monitoring well sampling results are provided in Appendices G and H, respectively. The Interim Land Use Control Implementation Plan (LUCIP) is provided as Appendix I. Monitoring well completion reports, other applicable field forms, survey data, and analytical laboratory reports are provided as Appendices J through M, respectively, in the electronic copy of this document. Selected Site photographs are provided in Appendix N. The interim groundwater monitoring plan and document revision log are included as Appendices O and P, respectively. KSC Electronic Data Deliverable (KEDD) files are provided on the attached compact disk.

Novel Power MOSFET-Based Expander for High Frequency Ultrasound Systems

PubMed Central

Choi, Hojong; Shung, K. Kirk

2014-01-01

The function of an expander is to obstruct the noise signal transmitted by the pulser so that it does not pass into the transducer or receive electronics, where it can produce undesirable ring-down in an ultrasound imaging application. The most common type is a diode-based expander, which is essentially a simple diode-pair, is widely used in pulse-echo measurements and imaging applications because of its simple architecture. However, diode-based expanders may degrade the performance of ultrasonic transducers and electronic components on the receiving and transmitting sides of the ultrasound systems, respectively. Since they are non-linear devices, they cause excessive signal attenuation and noise at higher frequencies and voltages. In this paper, a new type of expander that utilizes power MOSFET components, which we call a power MOSFET-based expander, is introduced and evaluated for use in high frequency ultrasound imaging systems. The performance of a power MOSFET-based expander was evaluated relative to a diode-based expander by comparing the noise figure (NF), insertion loss (IL), total harmonic distortion (THD), response time (RT), electrical impedance (EI) and dynamic power consumption (DPC). The results showed that the power MOSFET-based expander provided better NF (0.76 dB), IL (-0.3 dB) and THD (-62.9 dB), and faster RT (82 ns) than did the diode-based expander (NF (2.6 dB), IL (-1.4 dB), THD (-56.0 dB) and RT (119 ns)) at 70 MHz. The -6 dB bandwidth and the peak-to-peak voltage of the echo signal received by the transducer using the power MOSFET-based expander improved by 17.4 % and 240 % compared to the diode-based expander, respectively. The new power MOSFET-based expander was shown to yield lower NF, IL and THD, faster RT and lower ring down than the diode-based expander at the expense of higher dynamic power consumption. PMID:23835308

Improvement in transmission loss of aircraft double wall with resonators

NASA Astrophysics Data System (ADS)

Sun, Jincai; Shi, Liming; Ye, Xining

1991-08-01

A little volume low frequency resonator applicable to double-wall configuration of propeller-driven aircraft was designed on the basis of the principle of Helmholtz resonator. The normal incidence absorption coefficient of the various single resonator has been measured. The agreement between theoretical and experimental results is encouraging. An array of resonators whose resonant frequency at 85 Hz and 160 Hz, respectively, are installed between aircraft double-panel, and it has been shown that transmission loss of the double wall structure with resonators improve 4 dB and 6.5 dB in 1/3rd octave bandwidth at 80 Hz and 160 Hz center frequency, respectively, and 5 dB and 7 dB at resonant frequencies, compared with that of the double wall configuration without resonators.

Application of derivative and derivative ratio spectrophotometry to simultaneous trace determination of rhodamine B and rhodamine 6G after dispersive liquid-liquid microextraction.

PubMed

Xiao, Ni; Deng, Jian; Huang, Kaihui; Ju, Saiqin; Hu, Canhui; Liang, Jun

2014-07-15

Two novel methods, first derivative spectrophotometric method ((1)D) and first derivative ratio spectrophotometric method ((1)DR), have been developed for the simultaneous trace determination of rhodamine B (RhB) and rhodamine 6G (Rh6G) in food samples after dispersive liquid-liquid microextraction (DLLME). The combination of derivative spectrophotometric techniques and DLLME procedure endows the presented methods with enhanced sensitivity and selectivity. Under optimum conditions, the linear calibration curves ranged from 5 to 450 ng mL(-1), with the correlation coefficients (r) of 0.9997 for RhB and 0.9977 for Rh6G by (1)D method, and 0.9987 for RhB and 0.9958 for Rh6G by (1)DR method, respectively. The calculated limits of detection (LODs) based on the variability of the blank solutions (S/N = 3 criterion) for 11 measurements were in the range of 0.48-1.93 ng mL(-1). The recoveries ranged from 88.1% to 111.6% (with RSD less than 4.4%) and 91.5-110.5% (with RSD less than 4.7%) for (1)D and (1)DR method, respectively. The influence of interfering substances such as foreign ions and food colorants which might be present in the food samples on the signals of RhB and Rh6G was examined. The developed methods have been successfully applied to the determination of RhB and Rh6G in black tea, red wine and chilli powder samples with the characteristics of simplicity, cost-effectiveness, environmental friendliness, and could be valuable for routine analysis. Copyright © 2014 Elsevier B.V. All rights reserved.

14 CFR 141.35 - Chief instructor qualifications.

Code of Federal Regulations, 2014 CFR

2014-01-01

... gliders, balloons, or airships, the chief instructor must meet the applicable requirements in paragraphs (b), (c), and (d) of this section; and (6) A chief instructor for a course of training for gliders...

14 CFR 141.35 - Chief instructor qualifications.

Code of Federal Regulations, 2012 CFR

2012-01-01

... gliders, balloons, or airships, the chief instructor must meet the applicable requirements in paragraphs (b), (c), and (d) of this section; and (6) A chief instructor for a course of training for gliders...

14 CFR 141.35 - Chief instructor qualifications.

Code of Federal Regulations, 2011 CFR

2011-01-01

... gliders, balloons, or airships, the chief instructor must meet the applicable requirements in paragraphs (b), (c), and (d) of this section; and (6) A chief instructor for a course of training for gliders...

14 CFR 141.35 - Chief instructor qualifications.

Code of Federal Regulations, 2013 CFR

2013-01-01

... gliders, balloons, or airships, the chief instructor must meet the applicable requirements in paragraphs (b), (c), and (d) of this section; and (6) A chief instructor for a course of training for gliders...

14 CFR 141.35 - Chief instructor qualifications.

Code of Federal Regulations, 2010 CFR

2010-01-01

... gliders, balloons, or airships, the chief instructor must meet the applicable requirements in paragraphs (b), (c), and (d) of this section; and (6) A chief instructor for a course of training for gliders...

A Multi-Band Body-Worn Distributed Radio-Frequency Exposure Meter: Design, On-Body Calibration and Study of Body Morphology

PubMed Central

Thielens, Arno; Agneessens, Sam; Van Torre, Patrick; Van den Bossche, Matthias; Eeftens, Marloes; Huss, Anke; Vermeulen, Roel; de Seze, René; Mazet, Paul; Cardis, Elisabeth; Röösli, Martin; Martens, Luc; Joseph, Wout

2018-01-01

A multi-band Body-Worn Distributed exposure Meter (BWDM) calibrated for simultaneous measurement of the incident power density in 11 telecommunication frequency bands, is proposed. The BDWM consists of 22 textile antennas integrated in a garment and is calibrated on six human subjects in an anechoic chamber to assess its measurement uncertainty in terms of 68% confidence interval of the on-body antenna aperture. It is shown that by using multiple antennas in each frequency band, the uncertainty of the BWDM is 22 dB improved with respect to single nodes on the front and back of the torso and variations are decreased to maximum 8.8 dB. Moreover, deploying single antennas for different body morphologies results in a variation up to 9.3 dB, which is reduced to 3.6 dB using multiple antennas for six subjects with various body mass index values. The designed BWDM, has an improved uncertainty of up to 9.6 dB in comparison to commercially available personal exposure meters calibrated on body. As an application, an average incident power density in the range of 26.7–90.8 μW·m−2 is measured in Ghent, Belgium. The measurements show that commercial personal exposure meters underestimate the actual exposure by a factor of up to 20.6. PMID:29346280

Recording Cultural Heritage Using Terrestrial Laserscanning - Dealing with the System, the Huge Datasets they Create and Ways to Extract the Necessary Deliverables you can Work with

NASA Astrophysics Data System (ADS)

Christofori, E.; Bierwagen, J.

2013-07-01

Recording Cultural Heritage objects using terrestrial laserscanning becomes more and more popular over the last years. Since terrestrial Laserscanning System (TLS) Manufacturers have strongly increased the amount and speed of data captured with a single scan at each system upgrade and cutting down system costs the use of TLS Systems for recording cultural heritage is an option for recording worth to think about beside traditional methods like Photogrammetric. TLS Systems can be a great tool for capturing complex cultural heritage object within a short amount of time beside the traditional methods but can be a nightmare to handle for further process if not used right while capturing. Furthermore TLS Systems still have to be recognized as survey equipment, even though some of the manufactures promote them as everyday tool. They have to be used in an intelligent way having in mind the clients and the individual cultural objects needs. Thus the efficient way to use TLS Systems for data recording becomes a relevant topic to deal with the huge Amount of data the Systems collect while recording. Already small projects can turn into huge Pointcloud Datasets that End user, like Architects or Archaeologist neither can't deal with as their technical equipment doesn't fit the requirements of the Dataset nor do they have the software tools to use the Data as the current software tools still are high prized. Even the necessary interpretation of the Dataset can be a tough task if the people who have to work on with the Pointcloud aren't educated right in order to understand TLS and the results it creates. The use of TLS Systems has to have in mind the project requirements of the individual Heritage Object, like the required accuracy, standards for Levels of Details (e.g. "Empfehlungen für die Baudokumentation, Günther Eckstein, Germany"), the required kind of Deliverables (Visualization, 2D Drawings, True Deformation Drawings, 3D Models, BIM or 4D - Animations) as well as the Projects budget, restrictions and special conditions of the object. And if it's used in the right way TLS will fulfil all request and furthermore create additional recording, deliverable and financial benefit. Christofori und Partner is working with TLS Systems on cultural heritage Objects since 2005 trying to optimize the use of these systems (even in combining different systems like TLS, photogrammetric or new techniques) as well as creating useable deliverables for the Clients (Owner, Conservator, Designers and the Public) they can work on with.

Circular Microstrip Antenna with Fractal Slots for Multiband Applications

NASA Astrophysics Data System (ADS)

Singh, Sivia Jagtar; Singh, Gurpreet; Bharti, Gurpreet

2017-10-01

In this paper, a multiband, fractal, slotted, Circular Microstrip Patch Antenna for GSM, WiMAX, C and X bands (satellite communication applications) is presented. A cantor set theory is used to make fractal slots for obtaining the desired multiband. The projected antenna is simulated using Ansys HFSS v13.0 software. Simulation test of this antenna has been carried out for a frequency range of 1 GHz-10 GHz and a peak gain of 9.19 dB at a resonance frequency of 1.9 GHz is obtained. The antenna also resonates at 3.7 GHz, 6.06 GHz and 7.9 GHz with gains of 3.04 dB, 5.19 dB and 5.39 dB respectively. Parameters like voltage standing wave ratio, return loss, and gain are used to compare the results of the projected antenna with conventional CMPA's of same dimensions with full and defective grounds. The projected antenna is fabricated on a glass epoxy material and is tested using Vector Network Analyzer. The performance parameters of the antenna are found to in good agreement with each both using simulated and measured data.

The Shock and Vibration Bulletin. Part 2. Isolation and Damping, Impact, Blast

DTIC Science & Technology

1978-09-01

Laboratory, WPAFB, Ohio; A.D. 13. L.C. Rogers, AFFDL/ FBG , WPAFB, CH, private , Nashif, Anatrol Corporation, Cincinnati, Ohio; communication. and J...to reconstruct the Differentiation with Application in ’ ’ function itself. A 6 dB/octave for the first Biomechanics ," Proc. Soc. Photo-optical V

Micro and Nano-mediated 3D Cardiac Tissue Engineering

DTIC Science & Technology

2012-09-01

as many forms of heart disease involve stiff scar tissue in the heart. Research Group: Larry Schook Period Sept ’11 to Sept ‘12 Deliverables...to their influence on cell attachment. Modeling disease systems and using recently developed biomaterials on PC biosensors with this new technique...will allow new insight into these problems, enabling researchers to develop more successful therapeutic approaches to clinical disease . VII

Research into the Specific Aspects of Internal Conflict Displays in the Course of Professional Identification

ERIC Educational Resources Information Center

Rensh, Marina A.; Kosyakova, Inessa V.; Agafonova, Anna N.

2016-01-01

The applicability of the researched issue is preconditioned by the need for detecting key determinants which define the process of the person's professional development, identification with the professional environment, and sources of professional self-efficacy. The purpose of the article is to provide the deliverables of the empiric research for…

Classroom Thoughtfulness and Students' Higher Order Thinking: Common Indicators and Diverse Social Studies Courses. Final Deliverable.

ERIC Educational Resources Information Center

Newmann, Fred M.

This project developed a conceptualization of higher order thinking, dimensions of classroom thoughtfulness, and an assessment exercise applicable to diverse topics taught in more than 70 classes in 11 high schools. Generic qualities of classroom thoughtfulness were not generally associated with the persuasiveness of student writing on a…

The Codacs™ direct acoustic cochlear implant actuator: exploring alternative stimulation sites and their stimulation efficiency.

PubMed

Grossöhmichen, Martin; Salcher, Rolf; Kreipe, Hans-Heinrich; Lenarz, Thomas; Maier, Hannes

2015-01-01

This work assesses the efficiency of the Codacs system actuator (Cochlear Ltd., Sydney Australia) in different inner ear stimulation modalities. Originally the actuator was intended for direct perilymph stimulation after stapedotomy using a piston prosthesis. A possible alternative application is the stimulation of middle ear structures or the round window (RW). Here the perilymph stimulation with a K-piston through a stapes footplate (SFP) fenestration (N = 10) as well as stimulation of the stapes head (SH) with a Bell prosthesis (N = 9), SFP stimulation with an Omega/Aerial prosthesis (N = 8) and reverse RW stimulation (N = 10) were performed in cadaveric human temporal bones (TBs). Codacs actuator output is expressed as equivalent sound pressure level (eq. SPL) using RW and SFP displacement responses, measured by Laser Doppler velocimetry as reference. The axial actuator coupling force in stimulation of stapes and RW was adjusted to ~5 mN. The Bell prosthesis and Omega/Aerial prosthesis stimulation generated similar mean eq. SPLs (Bell: 127.5-141.8 eq. dB SPL; Omega/Aerial: 123.6-143.9 eq. dB SPL), being significantly more efficient than K-piston perilymph stimulation (108.6-131.6 eq. dB SPL) and RW stimulation (108.3-128.2 eq. dB SPL). Our results demonstrate that SH, SFP and RW are adequate alternative stimulation sites for the Codacs actuator using coupling prostheses and an axial coupling force of ~5 mN. Based on the eq. SPLs, all investigated methods were adequate for in vivo hearing aid applications, provided that experimental conditions including constant coupling force will be implemented.

77 FR 72872 - National Institute of Neurological Disorders and Stroke; Notice of Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-06

... set forth in sections 552b(c)(4) and 552b(c)(6), Title 5 U.S.C., as amended. The grant applications... Associate Director for Extramural Research; and Administrative and Program Developments. Place: National..., Bethesda, MD 20892. Contact Person: Robert Finkelstein, Ph.D., Associate Director for Extramural Research...

76 FR 51043 - National Institute of Neurological Disorders and Stroke; Notice of Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-17

... set forth in sections 552b(c)(4) and 552b(c)(6), Title 5 U.S.C., as amended. The grant applications... Director for Extramural Research, NINDS; and Other Administrative and Program Developments. Place: National... Person: Robert Finkelstein, PhD, Associate Director for Extramural Research, National Institute of...

Randomized comparison of deliverability and in-hospital complications in implantation of BxSonic(R), Express(R), and Flexmaster(R) coronary stents.

PubMed

Thuesen, Leif; Galløe, Anders; Thayssen, Per; Rasmussen, Klaus; Kelbæk, Henning; Lassen, Jens Flensted; Hansen, Peter Riis; Pedersen, Knud Erik; Ravkilde, Jan; Helquist, Steffen; Abildgaard, Ulrik; Andersen, Henning Rud; Bøtker, Hans Erik; Kristensen, Steen Dalby; Hjort, Jacob; Krusell, Lars Romer

2005-11-01

To compare deliverability and in-hospital complications in implantation of BxSonic(R), Express(R), and Flexmaster(R) coronary stents in a randomized multicenter trial in five Danish interventional centres. Patients with planned stenting of at least one stenotic lesion in a native coronary artery were included in the study. There were 494 (664) patients (treated lesions) in the BxSonic(R), 499 (657) in the Express(R) and 500 (658) in the Flexmaster(R) groups. The groups were well matched with regard to age, sex, diabetes, smoking, hypercholesterolemia, hypertension, indication for PCI and coronary artery lesion complexity. The study stents were implanted with or without predilatation according to ordinary -clinical practice.Rates of successful stent implantation and in-hospital stent thrombosis, re-intervention, non-fatal myocardial infarction or death. The BxSonic(R), Express(R) and Flexmaster(R) stents were successfully implanted in 92,2%, 89,3% and 91,6% of all lesions (ns). There were no in-hospital deaths and the rates of in-hospital complications were similar in the three stent groups. We found similar deliverability and in-hospital complication rates of the BxSonic(R), Express(R) and Flexmaster(R) stents.

An inductorless active mixer using stacked nMOS/pMOS configuration and LO shaping technique

NASA Astrophysics Data System (ADS)

Guo, Benqing; Chen, Jun; Wang, Xuebing; Chen, Hongpeng

2018-04-01

In this paper, a CMOS active down-conversion mixer is presented for wideband applications. Specifically, a LO generation chain is suggested to convert AC LO signal to shaped trapezoid burst, which reduces the sinusoidal LO power level requirement by the mixer. The current-reuse technique by stacked nMOS/pMOS architecture is used to save the power consumption of the circuit. Moreover, this complementary configuration is also employed to compensate second-order nonlinearity of the circuit. Implemented in a 0.18-μm CMOS process, post-simulations show that, driven by only ‑10 dBm sinusoidal LO signal, the proposed inductorless mixer provides a maximal conversion gain of 15.7 dB and a noise figure (NF) of 9.1-12 dB across RF input frequency range 0.5-1.6 GHz. The IIP3 and IP1dB of 3.5 dBm and ‑4.8 dBm are obtained, respectively. The mixer core only consumes 3.6 mW from a 1.8-V supply.

Microcomputers and the Electrical Engineer.

DTIC Science & Technology

1984-07-01

B6 10*SIN(B4*B1I) 12 BII+B6 10*SIN(B4*812) 13 B12+B6 1O*SIN(B4*BI3) 14 B13+B6 10*SIN(B4*B14) 15 B14+B6 10*SIN(B4*BI5) 16 B15+B6 10*SIN(B4* Bl6 ) 17 B16 ...C15)),AND(D15,NOT(EI5 16 0 0 1 0 OR(AND( B16 ,NOT(C16)),AND(D16,NOT(E16 a17 0 0 0 1 OR(AND(B17,NOT(C17)),AND(D17,NOT(E17 18 0 0 0 0 OR(AND(B18,NOT(C18...NOT(E15)) 16 0 0 010 AND(AND( Bl6 ,NOT(Cl7)),AND(D16,NOT(E16)) 18 0) 0 0 0 AND(AND(B18,NOT(C18)),AND(D18,NOT(E18)) 19 Figure 3 I A IIBIJCIIDIIEII F I 1

Incorporating deliverable monitor unit constraints into spot intensity optimization in intensity modulated proton therapy treatment planning

PubMed Central

Cao, Wenhua; Lim, Gino; Li, Xiaoqiang; Li, Yupeng; Zhu, X. Ronald; Zhang, Xiaodong

2014-01-01

The purpose of this study is to investigate the feasibility and impact of incorporating deliverable monitor unit (MU) constraints into spot intensity optimization in intensity modulated proton therapy (IMPT) treatment planning. The current treatment planning system (TPS) for IMPT disregards deliverable MU constraints in the spot intensity optimization (SIO) routine. It performs a post-processing procedure on an optimized plan to enforce deliverable MU values that are required by the spot scanning proton delivery system. This procedure can create a significant dose distribution deviation between the optimized and post-processed deliverable plans, especially when small spot spacings are used. In this study, we introduce a two-stage linear programming (LP) approach to optimize spot intensities and constrain deliverable MU values simultaneously, i.e., a deliverable spot intensity optimization (DSIO) model. Thus, the post-processing procedure is eliminated and the associated optimized plan deterioration can be avoided. Four prostate cancer cases at our institution were selected for study and two parallel opposed beam angles were planned for all cases. A quadratic programming (QP) based model without MU constraints, i.e., a conventional spot intensity optimization (CSIO) model, was also implemented to emulate the commercial TPS. Plans optimized by both the DSIO and CSIO models were evaluated for five different settings of spot spacing from 3 mm to 7 mm. For all spot spacings, the DSIO-optimized plans yielded better uniformity for the target dose coverage and critical structure sparing than did the CSIO-optimized plans. With reduced spot spacings, more significant improvements in target dose uniformity and critical structure sparing were observed in the DSIO- than in the CSIO-optimized plans. Additionally, better sparing of the rectum and bladder was achieved when reduced spacings were used for the DSIO-optimized plans. The proposed DSIO approach ensures the deliverability of optimized IMPT plans that take into account MU constraints. This eliminates the post-processing procedure required by the TPS as well as the resultant deteriorating effect on ultimate dose distributions. This approach therefore allows IMPT plans to adopt all possible spot spacings optimally. Moreover, dosimetric benefits can be achieved using smaller spot spacings. PMID:23835656

Bipolar-power-transistor-based limiter for high frequency ultrasound imaging systems.

PubMed

Choi, Hojong; Yang, Hao-Chung; Shung, K Kirk

2014-03-01

High performance limiters are described in this paper for applications in high frequency ultrasound imaging systems. Limiters protect the ultrasound receiver from the high voltage (HV) spikes produced by the transmitter. We present a new bipolar power transistor (BPT) configuration and compare its design and performance to a diode limiter used in traditional ultrasound research and one commercially available limiter. Limiter performance depends greatly on the insertion loss (IL), total harmonic distortion (THD) and response time (RT), each of which will be evaluated in all the limiters. The results indicated that, compared with commercial limiter, BPT-based limiter had less IL (-7.7 dB), THD (-74.6 dB) and lower RT (43 ns) at 100 MHz. To evaluate the capability of these limiters, they were connected to a 100 MHz single element transducer and a two-way pulse-echo test was performed. It was found that the -6 dB bandwidth and sensitivity of the transducer using BPT-based limiter were better than those of the commercial limiter by 22% and 140%, respectively. Compared to the commercial limiter, BPT-based limiter is shown to be capable of minimizing signal attenuation, RT and THD at high frequencies and is thus suited for high frequency ultrasound applications. Copyright © 2013 Elsevier B.V. All rights reserved.

Application of derivative and derivative ratio spectrophotometry to simultaneous trace determination of rhodamine B and rhodamine 6G after dispersive liquid-liquid microextraction

NASA Astrophysics Data System (ADS)

Xiao, Ni; Deng, Jian; Huang, Kaihui; Ju, Saiqin; Hu, Canhui; Liang, Jun

2014-07-01

Two novel methods, first derivative spectrophotometric method (1D) and first derivative ratio spectrophotometric method (1DR), have been developed for the simultaneous trace determination of rhodamine B (RhB) and rhodamine 6G (Rh6G) in food samples after dispersive liquid-liquid microextraction (DLLME). The combination of derivative spectrophotometric techniques and DLLME procedure endows the presented methods with enhanced sensitivity and selectivity. Under optimum conditions, the linear calibration curves ranged from 5 to 450 ng mL-1, with the correlation coefficients (r) of 0.9997 for RhB and 0.9977 for Rh6G by 1D method, and 0.9987 for RhB and 0.9958 for Rh6G by 1DR method, respectively. The calculated limits of detection (LODs) based on the variability of the blank solutions (S/N = 3 criterion) for 11 measurements were in the range of 0.48-1.93 ng mL-1. The recoveries ranged from 88.1% to 111.6% (with RSD less than 4.4%) and 91.5-110.5% (with RSD less than 4.7%) for 1D and 1DR method, respectively. The influence of interfering substances such as foreign ions and food colorants which might be present in the food samples on the signals of RhB and Rh6G was examined. The developed methods have been successfully applied to the determination of RhB and Rh6G in black tea, red wine and chilli powder samples with the characteristics of simplicity, cost-effectiveness, environmental friendliness, and could be valuable for routine analysis.

Search for rare and forbidden decays D+ --> h+/- e+/- e+.

PubMed

He, Q; Muramatsu, H; Park, C S; Thorndike, E H; Coan, T E; Gao, Y S; Liu, F; Artuso, M; Boulahouache, C; Blusk, S; Butt, J; Dorjkhaidav, O; Li, J; Menaa, N; Mountain, R; Nandakumar, R; Randrianarivony, K; Redjimi, R; Sia, R; Skwarnicki, T; Stone, S; Wang, J C; Zhang, K; Csorna, S E; Bonvicini, G; Cinabro, D; Dubrovin, M; Briere, R A; Chen, G P; Chen, J; Ferguson, T; Tatishvili, G; Vogel, H; Watkins, M E; Rosner, J L; Adam, N E; Alexander, J P; Berkelman, K; Cassel, D G; Crede, V; Duboscq, J E; Ecklund, K M; Ehrlich, R; Fields, L; Galik, R S; Gibbons, L; Gittelman, B; Gray, R; Gray, S W; Hartill, D L; Heltsley, B K; Hertz, D; Jones, C D; Kandaswamy, J; Kreinick, D L; Kuznetsov, V E; Mahlke-Krüger, H; Meyer, T O; Onyisi, P U E; Patterson, J R; Peterson, D; Phillips, E A; Pivarski, J; Riley, D; Ryd, A; Sadoff, A J; Schwarthoff, H; Shi, X; Shepherd, M R; Stroiney, S; Sun, W M; Urner, D; Wilksen, T; Weaver, K M; Weinberger, M; Athar, S B; Avery, P; Breva-Newell, L; Patel, R; Potlia, V; Stoeck, H; Yelton, J; Rubin, P; Cawlfield, C; Eisenstein, B I; Gollin, G D; Karliner, I; Kim, D; Lowrey, N; Naik, P; Sedlack, C; Selen, M; White, E J; Williams, J; Wiss, J; Asner, D M; Edwards, K W; Besson, D; Pedlar, T K; Cronin-Hennessy, D; Gao, K Y; Gong, D T; Hietala, J; Kubota, Y; Klein, T; Lang, B W; Li, S Z; Poling, R; Scott, A W; Smith, A; Dobbs, S; Metreveli, Z; Seth, K K; Tomaradze, A; Zweber, P; Ernst, J; Severini, H; Dytman, S A; Love, W; Mehrabyan, S; Mueller, J A; Savinov, V; Li, Z; Lopez, A; Mendez, H; Ramirez, J; Huang, G S; Miller, D H; Pavlunin, V; Sanghi, B; Shipsey, I P J; Adams, G S; Cravey, M; Cummings, J P; Danko, I; Napolitano, J

2005-11-25

Using 0.8 x 10(6) D+ D- pairs collected with the CLEO-c detector at the psi(3770) resonance, we have searched for flavor-changing neutral current and lepton-number-violating decays of D+ mesons to final states with dielectrons. We find no indication of either, obtaining 90% confidence level upper limits of B(D+ --> pi+ e+ e-) < 7.4 x 10(-6), B(D+ --> pi- e+ d+) < 3.6 x 10(-6), B(D+ --> K+ e+ e-) < 6.2 x 10(-6), and B(D+ --> K- e+ e+) < 4.5 x 10(-6).

Optimization of Parameters for Semiempirical Methods 2. Applications

DTIC Science & Technology

1989-01-01

A1OF 2 AIF 20 -265.0 -208.5 56.5 62.5 124.6 d AIF 3 Aluminum trifluoride -289.0 -291.5 -2.5 -2.3 71.3 d AIF 4 A1F 4 (-) Ion... trifluoride -38.0 -22.1 15.9 116.7 58.2 bFCl Chlorine pentafluoride -54.0 -54.0 0.0 258.8 144.5 b SOC12 Thionyl chloride -50.8 -47.6 3.2 28.6 43.1 e... Chlorine trifluoride C2v CIF 1.598 1.671 0.073 0.101 0.085 a CIF’ 1.698 1.671 -0.027 0,001 -0.015 FC1F’ 87.5 120.0 32.5 32.5 32.5 Cl 2 Chlorine CICI

Power Amplifier Linearizer for High Frequency Medical Ultrasound Applications

PubMed Central

Choi, Hojong; Jung, Hayong; Shung, K. Kirk

2015-01-01

Power amplifiers (PAs) are used to produce high-voltage excitation signals to drive ultrasonic transducers. A larger dynamic range of linear PAs allows higher contrast resolution, a highly desirable characteristic in ultrasonic imaging. The linearity of PAs can be improved by reducing the nonlinear harmonic distortion components of high-voltage output signals. In this paper, a linearizer circuit is proposed to reduce output signal harmonics when working in conjunction with a PA. The PA performance with and without the linearizer was measured by comparing the output power 1-dB compression point (OP1dB), and the second- and third-order harmonic distortions (HD2 and HD3, respectively). The results show that the PA with the linearizer circuit had higher OP1dB (31.7 dB) and lower HD2 (−61.0 dB) and HD3 (−42.7 dB) compared to those of the PA alone (OP1dB (27.1 dB), HD2 (−38.2 dB), and HD3 (−36.8 dB)) at 140 MHz. A pulse-echo measurement was also performed to further evaluate the capability of the linearizer circuit. The HD2 of the echo signal received by the transducer using a PA with the linearizer (−24.8 dB) was lower than that obtained for the PA alone (−16.6 dB). The linearizer circuit is capable of improving the linearity performance of PA by lowering harmonic distortions. PMID:26622209

Proceedings of the 2007 Antenna Applications Symposium. Volume 2

DTIC Science & Technology

2007-12-20

field strength at 1 km [1]. It is based on an ideal short monopole, with 1 kW available power and no earth losses. Losses from the ideal monopole are...antenna operates over UHF and L Bands, providing ground- based transmit/receive capability for next generation radios. Filters are integrated into...enclosed in a housing which also serves as the base of the antenna (see Figure 6). The filters achieve approximately 40 dB (UHF low-pass) and 50 dB

Photoinduced Electronic Energy Transfer: Theoretical and Experimental Issues for Light Harvesting Applications

DTIC Science & Technology

2013-10-21

PHOTOINDUCED ELECTRONIC ENERGY TRANSFER - THEORETICAL AND EXPERIMENTAL ISSUES FOR LIGHT HARVESTING APPLICATIONS PAUL BRUMER UNIV OF TORONTO 10/21... Applications 5a. CONTRACT NUMBER 5b. GRANT NUMBER FA9550-10-1-0260 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT...Harvesting Applications Grant Number: FA9550-10-1-0260 Program Manager: Dr. Tatjana Curcic, AFOSR Stated aims of the project

Assessment of noise exposure for basketball sports referees.

PubMed

Masullo, Massimiliano; Lenzuni, Paolo; Maffei, Luigi; Nataletti, Pietro; Ciaburro, Giuseppe; Annesi, Diego; Moschetto, Antonio

2016-01-01

Dosimetric measurements carried out on basketball referees have shown that whistles not only generate very high peak sound pressure levels, but also play a relevant role in determining the overall exposure to noise of the exposed subjects. Because of the peculiar geometry determined by the mutual positions of the whistle, the microphone, and the ear, experimental data cannot be directly compared with existing occupational noise exposure and/or action limits. In this article, an original methodology, which allows experimental results to be reliably compared with the aforementioned limits, is presented. The methodology is based on the use of two correction factors to compensate the effects of the position of the dosimeter microphone (fR) and of the sound source (fS). Correction factors were calculated by means of laboratory measurements for two models of whistles (Fox 40 Classic and Fox 40 Sonik) and for two head orientations (frontal and oblique).Results sho w that for peak sound pressure levels the values of fR and fS, are in the range -8.3 to -4.6 dB and -6.0 to -1.7 dB, respectively. If one considers the Sound Exposure Levels (SEL) of whistle events, the same correction factors are in the range of -8.9 to -5.3 dB and -5.4 to -1.5 dB, respectively. The application of these correction factors shows that the corrected weekly noise exposure level for referees is 80.6 dB(A), which is slightly in excess of the lower action limit of the 2003/10/EC directive, and a few dB below the Recommended Exposure Limit (REL) proposed by the National Institute for Occupational Safety and Health (NIOSH). The corrected largest peak sound pressure level is 134.7 dB(C) which is comparable to the lower action limit of the 2003/10/EC directive, but again substantially lower than the ceiling limit of 140 dB(A) set by NIOSH.

Scientific Visualization for Atmospheric Data Analysis in Collaborative Virtual Environments

NASA Astrophysics Data System (ADS)

Engelke, Wito; Flatken, Markus; Garcia, Arturo S.; Bar, Christian; Gerndt, Andreas

2016-04-01

1 INTRODUCTION The three year European research project CROSS DRIVE (Collaborative Rover Operations and Planetary Science Analysis System based on Distributed Remote and Interactive Virtual Environments) started in January 2014. The research and development within this project is motivated by three use case studies: landing site characterization, atmospheric science and rover target selection [1]. Currently the implementation for the second use case is in its final phase [2]. Here, the requirements were generated based on the domain experts input and lead to development and integration of appropriate methods for visualization and analysis of atmospheric data. The methods range from volume rendering, interactive slicing, iso-surface techniques to interactive probing. All visualization methods are integrated in DLR's Terrain Rendering application. With this, the high resolution surface data visualization can be enriched with additional methods appropriate for atmospheric data sets. This results in an integrated virtual environment where the scientist has the possibility to interactively explore his data sets directly within the correct context. The data sets include volumetric data of the martian atmosphere, precomputed two dimensional maps and vertical profiles. In most cases the surface data as well as the atmospheric data has global coverage and is of time dependent nature. Furthermore, all interaction is synchronized between different connected application instances, allowing for collaborative sessions between distant experts. 2 VISUALIZATION TECHNIQUES Also the application is currently used for visualization of data sets related to Mars the techniques can be used for other data sets as well. Currently the prototype is capable of handling 2 and 2.5D surface data as well as 4D atmospheric data. Specifically, the surface data is presented using an LoD approach which is based on the HEALPix tessellation of a sphere [3, 4, 5] and can handle data sets in the order of terabytes. The combination of different data sources (e.g., MOLA, HRSC, HiRISE) and selection of presented data (e.g., infrared, spectral, imagery) is also supported. Furthermore, the data is presented unchanged and with the highest possible resolution for the target setup (e.g., power-wall, workstation, laptop) and view distance. The visualization techniques for the volumetric data sets can handle VTK [6] based data sets and also support different grid types as well as a time component. In detail, the integrated volume rendering uses a GPU based ray casting algorithm which was adapted to work in spherical coordinate systems. This approach results in interactive frame-rates without compromising visual fidelity. Besides direct visualization via volume rendering the prototype supports interactive slicing, extraction of iso-surfaces and probing. The latter can also be used for side-by-side comparison and on-the-fly diagram generation within the application. Similarily to the surface data a combination of different data sources is supported as well. For example, the extracted iso-surface of a scalar pressure field can be used for the visualization of the temperature. The software development is supported by the ViSTA VR-toolkit [7] and supports different target systems as well as a wide range of VR-devices. Furthermore, the prototype is scalable to run on laptops, workstations and cluster setups. REFERENCES [1] A. S. Garcia, D. J. Roberts, T. Fernando, C. Bar, R. Wolff, J. Dodiya, W. Engelke, and A. Gerndt, "A collaborative workspace architecture for strengthening collaboration among space scientists," in IEEE Aerospace Conference, (Big Sky, Montana, USA), 7-14 March 2015. [2] W. Engelke, "Mars Cartography VR System 2/3." German Aerospace Center (DLR), 2015. Project Deliverable D4.2. [3] E. Hivon, F. K. Hansen, and A. J. Banday, "The healpix primer," arXivpreprint astro-ph/9905275, 1999. [4] K. M. Gorski, E. Hivon, A. Banday, B. D. Wandelt, F. K. Hansen, M. Reinecke, and M. Bartelmann, "Healpix: a framework for high-resolution discretization and fast analysis of data distributed on the sphere," The Astrophysical Journal, vol. 622, no. 2, p. 759, 2005. [5] R. Westerteiger, A. Gerndt, and B. Hamann, "Spherical terrain render- ing using the hierarchical healpix grid," VLUDS, vol. 11, pp. 13-23, 2011. [6] W. Schroeder, K. Martin, and B. Lorensen, The Visualization Toolkit. Kitware, 4 ed., 2006. [7] T. van Reimersdahl, T. Kuhlen, A. Gerndt, J. Henrichs, and C. Bischof, "ViSTA: a multimodal, platform-independent VR-toolkit based on WTK, VTK, and MPI," in Proceedings of the 4th International Immersive Projection Technology Workshop (IPT), 2000.

Image Alignment and Correlation System.

DTIC Science & Technology

1980-07-01

4 degrees in 0.1 degree steps would require 40 evaluations of SUM. Other search techniques such as Fibonacci and golden section 3 were investigated...in software, and particularly its refinement to suit the characteristics of the sensor, also represent a significant achievement in the application...86-07 LDAA #7 A23F BD 80 00 JSR MATH A242 4F CLRA A243 BD BB B4 JSR PUSH41 A246 CE lE 6C LDX #ARRAY+44D A249 4F CLRA A24A BD B BE JSR PUSH44 D A24D

Information Acquisition, Analysis and Integration

DTIC Science & Technology

2016-08-03

of sensing and processing, theory, applications, signal processing, image and video processing, machine learning , technology transfer. 16. SECURITY... learning . 5. Solved elegantly old problems like image and video debluring, intro- ducing new revolutionary approaches. 1 DISTRIBUTION A: Distribution...Polatkan, G. Sapiro, D. Blei, D. B. Dunson, and L. Carin, “ Deep learning with hierarchical convolution factor analysis,” IEEE 6 DISTRIBUTION A

26 CFR 1.414(c)-6 - Effective date.

Code of Federal Regulations, 2011 CFR

2011-04-01

..., 1974. (b) Existing plans. In the case of a plan in existence on January 1, 1974, unless paragraph (c... § 1.410(a)-2(c). (c) Existing plans electing new provisions. In the case of a plan in existence on....410 (a)-2 (d). (d) Application. For purposes of the Employee Retirement Income Security Act of 1974...

26 CFR 1.414(c)-6 - Effective date.

Code of Federal Regulations, 2010 CFR

2010-04-01

..., 1974. (b) Existing plans. In the case of a plan in existence on January 1, 1974, unless paragraph (c... § 1.410(a)-2(c). (c) Existing plans electing new provisions. In the case of a plan in existence on....410 (a)-2 (d). (d) Application. For purposes of the Employee Retirement Income Security Act of 1974...

44 CFR 70.6 - Distribution of Letter of Map Amendment.

Code of Federal Regulations, 2010 CFR

2010-10-01

... FOR MAP CORRECTION Mapping Deficiencies Unrelated to Community-Wide Elevation Determinations § 70.6... applicant who submitted scientific or technical data to the Federal Insurance Administrator. (b) A copy of... which it is amending. (d) A copy of the Letter of Map Amendment will be sent to any community or...

44 CFR 70.6 - Distribution of Letter of Map Amendment.

Code of Federal Regulations, 2011 CFR

2011-10-01

... FOR MAP CORRECTION Mapping Deficiencies Unrelated to Community-Wide Elevation Determinations § 70.6... applicant who submitted scientific or technical data to the Federal Insurance Administrator. (b) A copy of... which it is amending. (d) A copy of the Letter of Map Amendment will be sent to any community or...

75 FR 16152 - National Heart, Lung, and Blood Institute; Notice of Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-31

... sections 552b(c)(4) and 552b(c)(6), Title 5 U.S.C., as amended. The grant applications and the discussions..., MD 20892. Contact Person: Stephen C. Mockrin, Ph.D., Director, Division of Extramural Research... show one form of identification (for example, a government-issued photo ID, driver's license, or...

78 FR 28229 - National Heart, Lung, and Blood Institute; Notice of Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-14

... sections 552b(c)(4) and 552b(c)(6), Title 5 U.S.C., as amended. The grant applications and/or contract...: Stephen C. Mockrin, Ph.D., Director, Division of Extramural Research Activities, National Heart, Lung, and... example, a government-issued photo ID, driver's license, or passport) and to state the purpose of their...

40 CFR Table 1 to Subpart Aaaa of... - Applicability of NESHAP General Provisions to Subpart AAAA

Code of Federal Regulations, 2010 CFR

2010-07-01

... reconstructed sources 63.6(e) Operation and maintenance requirements, startup, shutdown and malfunction plan...(b)(2)(i)-(b)(2)(v) General recordkeeping requirements 63.10(d)(5) If actions taken during a startup, shutdown and malfunction plan are consistent with the procedures in the startup, shutdown and malfunction...

40 CFR Table 1 to Subpart Aaaa of... - Applicability of NESHAP General Provisions to Subpart AAAA

Code of Federal Regulations, 2011 CFR

2011-07-01

... reconstructed sources 63.6(e) Operation and maintenance requirements, startup, shutdown and malfunction plan...(b)(2)(i)-(b)(2)(v) General recordkeeping requirements 63.10(d)(5) If actions taken during a startup, shutdown and malfunction plan are consistent with the procedures in the startup, shutdown and malfunction...

21 CFR 1310.06 - Content of records and reports.

Code of Federal Regulations, 2010 CFR

2010-04-01

... exempted from §§ 1300.02(b)(28)(i)(D) or 1300.02(b)(28)(i)(E) during the preceding calendar year. (6) Data shall identify the specific isomer, salt or ester when applicable but quantitative data shall be....). (9) Number of dosage units (if drug product) (100 doses per package). (10) Package type (if drug...

SU-E-T-106: Development of a Collision Prediction Algorithm for Determining Problematic Geometry for SBRT Treatments Using a Stereotactic Body Frame

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wagar, M; Friesen, S; Mannarino, E

2014-06-01

Purpose: Collision between the gantry and the couch or patient during Radiotherapy is not a common concern for conventional RT (static fields or arc). With the increase in the application of stereotactic planning techniques to the body, collisions have become a greater concern. Non-coplanar beam geometry is desirable in stereotatic treatments in order to achieve sharp gradients and a high conformality. Non-coplanar geometry is less intuitive in the body and often requires an iterative process of planning and dry runs to guarantee deliverability. Methods: Purpose written software was developed in order to predict the likelihood of collision between the headmore » of the gantry and the couch, patient or stereotatic body frame. Using the DICOM plan and structures set, exported by the treatment planning system, this software is able to predict the possibility of a collision. Given the plan's isocenter, treatment geometry and exterior contours, the software is able to determine if a particular beam/arc is clinically deliverable or if collision is imminent. Results: The software was tested on real world treatment plans with untreatable beam geometry. Both static non-coplanar and VMAT plans were tested. Of these, the collision prediction software could identify all as having potentially problematic geometry. Re-plans of the same cases were also tested and validated as deliverable. Conclusion: This software is capable of giving good initial indication of deliverability for treatment plans that utilize complex geometry (SBRT) or have lateral isocenters. This software is not intended to replace the standard pre-treatment QA dry run. The effectiveness is limited to those portions of the patient and immobilization devices that have been included in the simulation CT and contoured in the planning system. It will however aid the planner in reducing the iterations required to create complex treatment geometries necessary to achieve ideal conformality and organ sparing.« less

Proposed Requirements-driven User-scenario Development Protocol for the Belmont Forum E-Infrastructure and Data Management Cooperative Research Agreement

NASA Astrophysics Data System (ADS)

Wee, B.; Car, N.; Percivall, G.; Allen, D.; Fitch, P. G.; Baumann, P.; Waldmann, H. C.

2014-12-01

The Belmont Forum E-Infrastructure and Data Management Cooperative Research Agreement (CRA) is designed to foster a global community to collaborate on e-infrastructure challenges. One of the deliverables is an implementation plan to address global data infrastructure interoperability challenges and align existing domestic and international capabilities. Work package three (WP3) of the CRA focuses on the harmonization of global data infrastructure for sharing environmental data. One of the subtasks under WP3 is the development of user scenarios that guide the development of applicable deliverables. This paper describes the proposed protocol for user scenario development. It enables the solicitation of user scenarios from a broad constituency, and exposes the mechanisms by which those solicitations are evaluated against requirements that map to the Belmont Challenge. The underlying principle of traceability forms the basis for a structured, requirements-driven approach resulting in work products amenable to trade-off analyses and objective prioritization. The protocol adopts the ISO Reference Model for Open Distributed Processing (RM-ODP) as a top level framework. User scenarios are developed within RM-ODP's "Enterprise Viewpoint". To harmonize with existing frameworks, the protocol utilizes the conceptual constructs of "scenarios", "use cases", "use case categories", and use case templates as adopted by recent GEOSS Architecture Implementation Project (AIP) deliverables and CSIRO's eReefs project. These constructs are encapsulated under the larger construct of "user scenarios". Once user scenarios are ranked by goodness-of-fit to the Belmont Challenge, secondary scoring metrics may be generated, like goodness-of-fit to FutureEarth science themes. The protocol also facilitates an assessment of the ease of implementing given user scenario using existing GEOSS AIP deliverables. In summary, the protocol results in a traceability graph that can be extended to coordinate across research programmes. If implemented using appropriate technologies and harmonized with existing ontologies, this approach enables queries, sensitivity analyses, and visualization of complex relationships.

Characterization of Cq3, a quantitative trait locus that controls plasma cholesterol and phospholipid levels in mice.

PubMed

Suto, Jun-ichi

2006-04-01

Cq3 was identified in C57BL/6J (B6) x KK-Ay F2 mice as a quantitative trait locus (QTL) that controls plasma cholesterol and phospholipid levels, and normolipidemic B6 allele was associated with increased lipids. Cq3 was statistically significant in F2-a/a, but not in F2-Ay/a; probably because the Cq3 effect was obscured by introduction of the Ay allele, which in itself has a strong hyperlipidemic effect. Because the peak LOD score for Cq3 was identified near D3Mit102 (49.7 cM) on chromosome 3, linkage analyses with microsatellite markers located at 49.7 cM were performed in KK x RR F2, B6 x RR F2, and KK x CF1 F2. However, even a suggestive QTL was not identified in any of the three F2. By testing all pairs of marker loci, I found a significant interaction between Cq3 and the Apoa2 locus, and F2 mice with the Apoa2(KK)/Apoa2(KK); D3Mit102(B6)/D3Mit102(B6) genotype had significantly higher cholesterol levels than did F2 mice with other genotypes. The results showed that the ;round-robin' strategy was not always applicable to the search for QTL genes; probably because specific gene-to-gene interaction limited the validity of the strategy to the utmost extent.

A Linear Programming Application to Aircrew Scheduling.

DTIC Science & Technology

1980-06-06

1968, our total force -- Air National Guard (ANG), Air Force Reserve (AFRES), and Active duty - aircraft inventory has dropped from over 15,000...3-3) I 8 Table 2 Active Duty A-7D Training Program Level A Level B Level C Day Night Day Night Sorties WD/SATa b 22/18 6 11/6 1 9/5 Maverick 6 4/2 2...and C are listed in % LTable 5. There are additional constraints not apparent from looking at the table. First, night events listed in Table 5 are only

The effect of statistical noise on IMRT plan quality and convergence for MC-based and MC-correction-based optimized treatment plans.

PubMed

Siebers, Jeffrey V

2008-04-04

Monte Carlo (MC) is rarely used for IMRT plan optimization outside of research centres due to the extensive computational resources or long computation times required to complete the process. Time can be reduced by degrading the statistical precision of the MC dose calculation used within the optimization loop. However, this eventually introduces optimization convergence errors (OCEs). This study determines the statistical noise levels tolerated during MC-IMRT optimization under the condition that the optimized plan has OCEs <100 cGy (1.5% of the prescription dose) for MC-optimized IMRT treatment plans.Seven-field prostate IMRT treatment plans for 10 prostate patients are used in this study. Pre-optimization is performed for deliverable beams with a pencil-beam (PB) dose algorithm. Further deliverable-based optimization proceeds using: (1) MC-based optimization, where dose is recomputed with MC after each intensity update or (2) a once-corrected (OC) MC-hybrid optimization, where a MC dose computation defines beam-by-beam dose correction matrices that are used during a PB-based optimization. Optimizations are performed with nominal per beam MC statistical precisions of 2, 5, 8, 10, 15, and 20%. Following optimizer convergence, beams are re-computed with MC using 2% per beam nominal statistical precision and the 2 PTV and 10 OAR dose indices used in the optimization objective function are tallied. For both the MC-optimization and OC-optimization methods, statistical equivalence tests found that OCEs are less than 1.5% of the prescription dose for plans optimized with nominal statistical uncertainties of up to 10% per beam. The achieved statistical uncertainty in the patient for the 10% per beam simulations from the combination of the 7 beams is ~3% with respect to maximum dose for voxels with D>0.5D(max). The MC dose computation time for the OC-optimization is only 6.2 minutes on a single 3 Ghz processor with results clinically equivalent to high precision MC computations.

STATS SRS v11.0

DOE Office of Scientific and Technical Information (OSTI.GOV)

Piscotty, M A; Nazario, O L

2007-06-20

The objective of this project is the delivery of an application that will provide a unified, web-based system for collecting, verifying and analyzing the achievements for Laboratory employees. The application will enable individual Directorates to manage and report achievement record data for their employees using an LLNL standard web browser. In addition, cross directorate data reporting and analysis will be available for such organizations as LSTO and programmatic directorates. This system is intended to store reference data and metadata for employee achievements. Abstracts and entire publications will not be stored in this system.Directorates are expected to use this system atmore » all levels of management in preparing for Annual Self-Assessments, peer reviews, LDRD reviews, work force reviews, performance appraisals, and requests from sponsors. This document represents the primary deliverable for the Requirements Definition stage of system development. As part of a successful Requirements Definition, this document provides the development staff, the project sponsor, and the user community with a clear understanding of the product's operational, data, and other requirements. With this understanding, the development staff will take the opportunity to refine estimates regarding the cost, schedule, and deliverables reflected in it.« less

Advancement and Application of Multi-Phase CFD Modeling to High Speed Supercavitating Flows

DTIC Science & Technology

2013-08-13

5a. CONTRACT NUMBER 5b. GRANT NUMBER N00014-09-1-0042 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Jules W. Lindau and Michael P. Kinzel 5d. PROJECT...REPORT U b. ABSTRACT U c. THIS PAGE U 17. LIMITATION OF ABSTRACT U 18. NUMBER OF PAGES 29 19a. NAME OF RESPONSIBLE PERSON Jules W. Lindau...Application of Multi-Phase CFD Modeling to High Speed Supercavitating Flows Michael P. Kinzel Jules W. Lindau Penn State University Applied Research

Inservice Education and the 6 O'Clock News. OSSC Bulletin Vol. 21, No. 7.

ERIC Educational Resources Information Center

Arends, Richard; And Others

Several assumptions currently held by many inservice planners and deliverers are presented and challenged. A new model of inservice programs is outlined that pays attention to the characteristics of maturing and growing professional educators and that demands new forms for delivering inservice to individuals and school clients. Inservice delivery…

76 FR 66685 - President's Export Council Subcommittee on Export Administration; Notice of Open Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-27

... public. 4. Review of Deliverables for the PEC. 5. Discussion of 2012 Workplan. 6. Subcommittee Breakout... which the United States has diplomatic or trading relations and of controlling trade for national....gov , no later than, November 7, 2011. A limited number of seats will be available for the public...

40 CFR 721.2088 - Carboxylic acids, (C6-C9) branched and linear.

Code of Federal Regulations, 2011 CFR

2011-07-01

... (a), (b), (c), (d), (f), (g)(3)(i), (g)(3)(ii), (g)(4)(iii) and (g)(5). (ii) Release to water. Requirements as specified in § 721.90 (a)(4), (b)(4), and (c)(4) (where N = 300 ppb for P-93-313, 314, and 315.... Recordkeeping requirements specified in § 721.125 (a), (b), (c), (f), (g), (h), and (k) are applicable to...

40 CFR 721.2088 - Carboxylic acids, (C6-C9) branched and linear.

Code of Federal Regulations, 2010 CFR

2010-07-01

... (a), (b), (c), (d), (f), (g)(3)(i), (g)(3)(ii), (g)(4)(iii) and (g)(5). (ii) Release to water. Requirements as specified in § 721.90 (a)(4), (b)(4), and (c)(4) (where N = 300 ppb for P-93-313, 314, and 315.... Recordkeeping requirements specified in § 721.125 (a), (b), (c), (f), (g), (h), and (k) are applicable to...

Resistance of the Brain to Escherichia coli K1 Infection Depends on MyD88 Signaling and the Contribution of Neutrophils and Monocytes

PubMed Central

Regen, Tommy; Meister, Tanja; Tauber, Simone C.; Schütze, Sandra; Mildner, Alexander; Mack, Matthias; Hanisch, Uwe-Karsten; Nau, Roland

2013-01-01

Escherichia coli is the leading cause of Gram-negative neonatal bacterial meningitis and also causes meningitis and meningoencephalitis in older and immunocompromised patients. Here, we determined the contribution of granulocytes, monocytes, and TLR signaling cascades in the resistance of adult mice to Escherichia coli K1 brain infection. Deficiency in MyD88 (myd88−/−) but not in TRIF (triflps2) adaptor proteins dramatically reduced the survival of animals. Depletion of CD11b+ Ly-6G+ Ly-6Cint neutrophils by application of the anti-Ly-6G (1A8) monoclonal antibody (MAb) led to higher bacterial loads in cerebellum and spleen tissue and resulted in increased mortality compared to those of isotype-treated controls. Depletion of CD11b+ Ly-6G+ Ly-6Cint neutrophils and CD11b+ Ly-6G− Ly-6Chigh monocytes by administration of the anti-Gr-1 (RB6-8C5) MAb rendered mice even more susceptible to the infection, with higher central nervous system (CNS) and spleen bacterial burdens than anti-Ly-6G-treated animals. Depletion of ∼50% of CD11b+ Ly-6G− Ly-6Chigh monocytes by injection of the anti-CCR2 (MC-21) MAb resulted in a trend toward higher mortality compared to that with isotype treatment. Production of interleukin 1β (IL-1β), IL-6, KC, and MIP-2 in the CNS strongly depended on the bacterial load: increased levels of these cytokines/chemokines were found after depletion of CD11b+ Ly-6G+ Ly-6Cint neutrophils alone or together with CD11b+ Ly-6G− Ly-6Chigh monocytes. These findings identify Toll-like receptor (TLR)-MyD88 signaling and neutrophil and monocyte activity as critical elements in the early host defense against E. coli meningitis. PMID:23478323

Resistance of the brain to Escherichia coli K1 infection depends on MyD88 signaling and the contribution of neutrophils and monocytes.

PubMed

Ribes, Sandra; Regen, Tommy; Meister, Tanja; Tauber, Simone C; Schütze, Sandra; Mildner, Alexander; Mack, Matthias; Hanisch, Uwe-Karsten; Nau, Roland

2013-05-01

Escherichia coli is the leading cause of Gram-negative neonatal bacterial meningitis and also causes meningitis and meningoencephalitis in older and immunocompromised patients. Here, we determined the contribution of granulocytes, monocytes, and TLR signaling cascades in the resistance of adult mice to Escherichia coli K1 brain infection. Deficiency in MyD88 (myd88(-/-)) but not in TRIF (trif(lps2)) adaptor proteins dramatically reduced the survival of animals. Depletion of CD11b(+) Ly-6G(+) Ly-6C(int) neutrophils by application of the anti-Ly-6G (1A8) monoclonal antibody (MAb) led to higher bacterial loads in cerebellum and spleen tissue and resulted in increased mortality compared to those of isotype-treated controls. Depletion of CD11b(+) Ly-6G(+) Ly-6C(int) neutrophils and CD11b(+) Ly-6G(-) Ly-6C(high) monocytes by administration of the anti-Gr-1 (RB6-8C5) MAb rendered mice even more susceptible to the infection, with higher central nervous system (CNS) and spleen bacterial burdens than anti-Ly-6G-treated animals. Depletion of ∼50% of CD11b(+) Ly-6G(-) Ly-6C(high) monocytes by injection of the anti-CCR2 (MC-21) MAb resulted in a trend toward higher mortality compared to that with isotype treatment. Production of interleukin 1β (IL-1β), IL-6, KC, and MIP-2 in the CNS strongly depended on the bacterial load: increased levels of these cytokines/chemokines were found after depletion of CD11b(+) Ly-6G(+) Ly-6C(int) neutrophils alone or together with CD11b(+) Ly-6G(-) Ly-6C(high) monocytes. These findings identify Toll-like receptor (TLR)-MyD88 signaling and neutrophil and monocyte activity as critical elements in the early host defense against E. coli meningitis.

Oral administration of d-limonene controls inflammation in rat colitis and displays anti-inflammatory properties as diet supplementation in humans.

PubMed

d'Alessio, Patrizia A; Ostan, Rita; Bisson, Jean-François; Schulzke, Joerg D; Ursini, Matilde V; Béné, Marie C

2013-07-10

To further explore the anti-inflammatory properties of d-Limonene. A rat model was used to compare evolution of TNBS (2,5,6-trinitrobenzene sulfonic acid)-induced colitis after oral feeding with d-Limonene compared to ibuprofen. Peripheral levels of TNF-α (Tumor Necrosis Factor alpha) were assessed in all animals. Cell cultures of fibroblasts and enterocytes were used to test the effect of d-Limonene respectively on TNFα-induced NF-κB (nuclear factor-kappa B) translocation and epithelial resistance. Finally, plasmatic inflammatory markers were examined in an observational study of diet supplementation with d-Limonene-containing orange peel extract (OPE) in humans. Administered per os at a dose of 10mg/kg p.o., d-Limonene induced a significant reduction of intestinal inflammatory scores, comparable to that induced by ibuprofen. Moreover, d-Limonene-fed rats had significantly lowered serum concentrations of TNF-α compared to untreated TNBS-colitis rats. The anti-inflammatory effect of d-Limonene also involved inhibition of TNFα-induced NF-κB translocation in fibroblast cultures. The application of d-Limonene on colonic HT-29/B6 cell monolayers increased epithelial resistance. Finally, inflammatory markers, especially peripheral IL-6, markedly decreased upon OPE supplementation of elderly healthy subjects submitted or not to 56 days of dietary supplementation with OPE. In conclusion, d-Limonene indeed demonstrates significant anti-inflammatory effects both in vivo and in vitro. Protective effects on the epithelial barrier and decreased cytokines are involved, suggesting a beneficial role of d-Limonene as diet supplement in reducing inflammation. Copyright © 2013 Elsevier Inc. All rights reserved.

United States and Mexican State Directors of Special Education: Information Exchange Meeting, February 7-9, 1999. Proceedings Document. Final Report, Deliverable-Task 2-3.1b.

ERIC Educational Resources Information Center

National Association of State Directors of Special Education, Alexandria, VA.

This proceedings documents a meeting designed to allow state directors of special education to exchange information about the special education systems in Mexico and the United States, to discuss common issues and concerns related to the provision of educational services for children and youth with disabilities, and to establish collegial…

Thiolated chitosans: design and in vivo evaluation of a mucoadhesive buccal peptide drug delivery system.

PubMed

Langoth, Nina; Kahlbacher, Hermann; Schöffmann, Gudrun; Schmerold, Ivo; Schuh, Maximilian; Franz, Sonja; Kurka, Peter; Bernkop-Schnürch, Andreas

2006-03-01

Intravenous application of pituitary adenylate cyclase-activating polypeptide (PACAP) has been identified as a promising strategy for the treatment of type 2 diabetes. To generate a more applicable formulation, it was the aim of this study to develop a sustained buccal delivery system for this promising therapeutic peptide. 2-Iminothiolane was covalently bound to chitosan to improve the mucoadhesive and permeation-enhancing properties of chitosan used as drug carrier matrix. The resulting chitosan-4-thiobutylamidine conjugate was homogenized with the enzyme inhibitor and permeation mediator glutathione (gamma-Glu-Cys-Gly), Brij 35, and PACAP (formulation A). The mixture was lyophilized and compressed into flat-faced discs (18 mm in diameter). One formulation was additionally coated on one side with palm wax (formulation B). Tablets consisting of unmodified chitosan and PACAP (formulation C) or of unmodified chitosan, Brij 35, and PACAP (formulation D) served as controls. Bioavailability studies were performed in pigs by buccal administration of these test formulations. Blood samples were analyzed via an ELISA method. Formulations A and B led to an absolute bioavailability of 1%, whereas PACAP did not reach the systemic circulation when administered via formulations C and D. Moreover, in the case of formulations A and B, a continuously raised plasma level of the peptide drug being in the therapeutic range could be maintained over the whole period of application (6 h). Formulations A and B were removed by moderate force from the buccal mucosa after 6 h, whereas formulations C and D detached from the mucosa 4 h after application. The study reveals this novel mucoadhesive delivery system to be a promising approach for buccal delivery of PACAP.

Engineering derivatives from biological systems for advanced aerospace applications

NASA Technical Reports Server (NTRS)

Winfield, Daniel L.; Hering, Dean H.; Cole, David

1991-01-01

The present study consisted of a literature survey, a survey of researchers, and a workshop on bionics. These tasks produced an extensive annotated bibliography of bionics research (282 citations), a directory of bionics researchers, and a workshop report on specific bionics research topics applicable to space technology. These deliverables are included as Appendix A, Appendix B, and Section 5.0, respectively. To provide organization to this highly interdisciplinary field and to serve as a guide for interested researchers, we have also prepared a taxonomy or classification of the various subelements of natural engineering systems. Finally, we have synthesized the results of the various components of this study into a discussion of the most promising opportunities for accelerated research, seeking solutions which apply engineering principles from natural systems to advanced aerospace problems. A discussion of opportunities within the areas of materials, structures, sensors, information processing, robotics, autonomous systems, life support systems, and aeronautics is given. Following the conclusions are six discipline summaries that highlight the potential benefits of research in these areas for NASA's space technology programs.

Assessment of post-contamination treatments affecting different bonding stages to dentin

PubMed Central

Elkassas, Dina; Arafa, Abla

2016-01-01

Objectives: To assess the effect of cleansing treatments following saliva and blood contamination at different bonding stages to dentin. Materials and Methods: Labial surfaces of 168 permanent maxillary central incisors were ground flat exposing superficial dentin. Specimens were divided into: uncontaminated control (A), contamination after etching (B), contamination after adhesive application (C), contamination after adhesive polymerization (D). Groups were further subdivided according to cleansing treatments into: rinsing (B1, C1, D1), re-etching (B2, D3), sodium hypochlorite application (B3), ethyl alcohol application (C2), acetone application (C3), rinsing and rebonding (D2), re-etching and rebonding (D4). Composite microcylinders were bonded to treated substrates and shear loaded micro-shear bond strength (μSBS) until failure and treated surfaces were examined with scanning electron microscope. Debonded surfaces were classified as adhesive, cohesive or mixed failure. The data were analyzed using one-way ANOVA and Tukey's post hoc test. Results: The μSBS values were ranked as follow; Group B: A > B3 > B2 > B1 > B, Group C: A > C3 > C2 > C1 > C, Group D: A > D4 > D1 = D2 ≥ D3. Debonded surfaces showed adhesive failure in Group B while cohesive failure in Groups C and D. Conclusions: Cleansing treatments differ according to bonding step; re-etching then rebonding suggested if etched substrate or polymerized adhesive were contaminated while acetone application decontaminated affected unpolymerized adhesive. PMID:27403048

78 FR 72720 - Arrow Investment Advisors, LLC, et al.; Notice of Application

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-03

... SECURITIES AND EXCHANGE COMMISSION [Investment Company Act Release No. 30813; File No. 812-14157] Arrow Investment Advisors, LLC, et al.; Notice of Application November 26, 2013. AGENCY: Securities and...(d), and 22(e) of the Act and rule 22c-1 under the Act, under sections 6(c) and 17(b) of the Act for...

The Codacs™ Direct Acoustic Cochlear Implant Actuator: Exploring Alternative Stimulation Sites and Their Stimulation Efficiency

PubMed Central

Grossöhmichen, Martin; Salcher, Rolf; Kreipe, Hans-Heinrich; Lenarz, Thomas; Maier, Hannes

2015-01-01

This work assesses the efficiency of the Codacs system actuator (Cochlear Ltd., Sydney Australia) in different inner ear stimulation modalities. Originally the actuator was intended for direct perilymph stimulation after stapedotomy using a piston prosthesis. A possible alternative application is the stimulation of middle ear structures or the round window (RW). Here the perilymph stimulation with a K-piston through a stapes footplate (SFP) fenestration (N = 10) as well as stimulation of the stapes head (SH) with a Bell prosthesis (N = 9), SFP stimulation with an Omega/Aerial prosthesis (N = 8) and reverse RW stimulation (N = 10) were performed in cadaveric human temporal bones (TBs). Codacs actuator output is expressed as equivalent sound pressure level (eq. SPL) using RW and SFP displacement responses, measured by Laser Doppler velocimetry as reference. The axial actuator coupling force in stimulation of stapes and RW was adjusted to ~ 5 mN. The Bell prosthesis and Omega/Aerial prosthesis stimulation generated similar mean eq. SPLs (Bell: 127.5–141.8 eq. dB SPL; Omega/Aerial: 123.6–143.9 eq. dB SPL), being significantly more efficient than K-piston perilymph stimulation (108.6–131.6 eq. dB SPL) and RW stimulation (108.3–128.2 eq. dB SPL). Our results demonstrate that SH, SFP and RW are adequate alternative stimulation sites for the Codacs actuator using coupling prostheses and an axial coupling force of ~ 5 mN. Based on the eq. SPLs, all investigated methods were adequate for in vivo hearing aid applications, provided that experimental conditions including constant coupling force will be implemented. PMID:25785860

A Flexible Sensing Unit Manufacturing Method of Electrochemical Seismic Sensor

PubMed Central

Li, Guanglei; Sun, Zhenyuan; Wang, Junbo; Chen, Deyong; Chen, Lianhong; Xu, Chao; Qi, Wenjie; Zheng, Yu

2018-01-01

This paper presents an electrochemical seismic sensor in which paraylene was used as a substrate and insulating layer of micro-fabricated electrodes, enabling the detection of seismic signals with enhanced sensitivities in comparison to silicon-based counterparts. Based on microfabrication, paralene-based electrochemical seismic sensors were fabricated in which the thickness of the insulating spacer was 6.7 μm. Compared to silicon-based counterparts with ~100 μm insulating layers, the parylene-based devices produced higher sensitivities of 490.3 ± 6.1 V/(m/s) vs. 192.2 ± 1.9 V/(m/s) at 0.1 Hz, 4764.4 ± 18 V/(m/s) vs. 318.9 ± 6.5 V/(m/s) at 1 Hz, and 4128.1 ± 38.3 V/(m/s) vs. 254.5 ± 4.2 V/(m/s) at 10 Hz. In addition, the outputs of the parylene vs. silicon devices in response to two transit inputs were compared, producing peak responses of 2.97 V vs. 0.22 V and 2.41 V vs. 0.19 V, respectively. Furthermore, the self-noises of parylene vs. silicon-based devices were compared as follows: −82.3 ± 3.9 dB vs. −90.4 ± 9.4 dB at 0.1 Hz, −75.7 ± 7.3 dB vs. −98.2 ± 9.9 dB at 1 Hz, and −62.4 ± 7.7 dB vs. −91.1 ± 8.1 dB at 10 Hz. The developed parylene-based electrochemical seismic sensors may function as an enabling technique for further detection of seismic motions in various applications. PMID:29641455

The 20 GHz GaAs monolithic power amplifier module development

NASA Technical Reports Server (NTRS)

1984-01-01

The development of a 20 GHz GaAs FET monlithic power amplifier module for advanced communication applications is described. Four-way power combing of four 0.6 W amplifier modules is used as the baseline approach. For this purpose, a monolithic four-way traveling-wave power divider/combiner was developed. Over a 20 GHz bandwidth (10 to 30 GHz), an insertion loss of no more than 1.2 dB was measured for a pair of back-to-back connected divider/combiners. Isolation between output ports is better than 20 dB, and VSWRs are better than 21:1. A distributed amplifier with six 300 micron gate width FETs and gate and drain transmission line tapers has been designed, fabricated, and evaluated for use as an 0.6 W module. This amplifier has achieved state-of-the-art results of 0.5 W output power with at least 4 dB gain across the entire 2 to 21 GHz frequency range. An output power of 2 W was achieved at a measurement frequency of 18 GHz when four distributed amplifiers were power-combined using a pair of traveling-wave divider/combiners. Another approach is the direct common-source cascading of three power FET stages. An output power of up to 2W with 12 dB gain and 20% power-added efficiency has been achieved with this approach (at 17 GHz). The linear gain was 14 dB at 1 W output. The first two stages of the three-stage amplifier have achieved an output power of 1.6 W with 9 dB gain and 26% power-added efficiency at 16 GHz.

Millimeter-wave pseudomorphic HEMT MMIC phased array components for space communications

NASA Technical Reports Server (NTRS)

Lan, G. L.; Pao, C. K.; Wu, C. S.; Mandolia, G.; Hu, M.; Yuan, S.; Leonard, Regis

1991-01-01

Recent advances in pseudomorphic HEMT MMIC (PMHEMT/MMIC) technology have made it the preferred candidate for high performance millimeter-wave components for phased array applications. This paper describes the development of PMHEMT/MMIC components at Ka-band and V-band. Specifically, the following PMHEMT/MMIC components will be described: power amplifiers at Ka-band; power amplifiers at V-band; and four-bit phase shifters at V-band. For the Ka-band amplifier, 125 mW output power with 5.5 dB gain and 21 percent power added efficiency at 2 dB compression point has been achieved. For the V-band amplifier, 112 mW output power with 6 dB gain and 26 percent power added efficiency has been achieved. And, for the V-band phase shifter, four-bit (45 deg steps) phase shifters with less than 8 dB insertion loss from 61 GHz to 63 GHz will be described.

Power Mems Development

DTIC Science & Technology

2010-11-30

testing and analysis in ONR laboratories. Task 1.2 Contributors: Sunny Kedia, Shinzo Onishi , Scott Samson, Drew Hanser Task 1.2 Deliverable...Priscila Spagnol, Shinzo Onishi , Drew Hanser, Weidong Wang, Sunny Kedia, John Bumgarner Deliverable: Prototype device fabricated on a thin-film diamond

Power Mems Development

DTIC Science & Technology

2010-12-31

laboratories. Task 1.2 Contributors: Sunny Kedia, Shinzo Onishi , Scott Samson, Drew Hanser Task 1.2 Deliverable: Functional MEMS-based DC-DC...Shinzo Onishi , Drew Hanser, Weidong Wang, Sunny Kedia, John Bumgarner Deliverable: Prototype device fabricated on a thin-film diamond heat spreader

Measurement of branching fractions and CP-violating charge asymmetries for B-meson decays to D{sup (*)}D{sup (*)}, and implications for the Cabibbo-Kobayashi-Maskawa angle {gamma}

DOE Office of Scientific and Technical Information (OSTI.GOV)

Aubert, B.; Barate, R.; Bona, M.

2006-06-01

We present measurements of the branching fractions and charge asymmetries of B decays to all D{sup (*)}D{sup (*)} modes. Using 232x10{sup 6} BB pairs recorded on the {upsilon}(4S) resonance by the BABAR detector at the e{sup +}e{sup -} asymmetric B factory PEP-II at the Stanford Linear Accelerator Center, we measure the branching fractions B(B{sup 0}{yields}D*{sup +}D*{sup -})=(8.1{+-}0.6{+-}1.0)x10{sup -4}, B(B{sup 0}{yields}D*{sup {+-}}D{sup {+-}})=(5.7{+-}0.7{+-}0.7)x10{sup -4}, B(B{sup 0}{yields}D{sup +}D{sup -})=(2.8{+-}0.4{+-}0.5)x10{sup -4}, B(B{sup +}{yields}D*{sup +}D*{sup 0})=(8.1{+-}1.2{+-}1.2)x10{sup -4}, B(B{sup +}{yields}D*{sup +}D{sup 0})=(3.6{+-}0.5{+-}0.4)x10{sup -4}, B(B{sup +}{yields}D{sup +}D*{sup 0})=(6.3{+-}1.4{+-}1.0)x10{sup -4}, and B(B{sup +}{yields}D{sup +}D{sup 0})=(3.8{+-}0.6{+-}0.5)x10{sup -4}, where in each case the first uncertainty is statistical and themore » second systematic. We also determine the limits B(B{sup 0}{yields}D*{sup 0}D*{sup 0})<0.9x10{sup -4}, B(B{sup 0}{yields}D*{sup 0}D{sup 0})<2.9x10{sup -4}, and B(B{sup 0}{yields}D{sup 0}D{sup 0})<0.6x10{sup -4}, each at 90% confidence level. All decays above denote either member of a charge-conjugate pair. We also determine the CP-violating charge asymmetries A(B{sup 0}{yields}D*{sup {+-}}D{sup {+-}})=0.03{+-}0.10{+-}0.02, A(B{sup +}{yields}D*{sup +}D*{sup 0})=-0.15{+-}0.11{+-}0.02, A(B{sup +}{yields}D*{sup +}D{sup 0})=-0.06{+-}0.13{+-}0.02, A(B{sup +}{yields}D{sup +}D*{sup 0})=0.13{+-}0.18{+-}0.04, and A(B{sup +}{yields}D{sup +}D{sup 0})=-0.13{+-}0.14{+-}0.02. Additionally, when we combine these results with information from time-dependent CP asymmetries in B{sup 0}{yields}D{sup (*)+}D{sup (*)-} decays and world-averaged branching fractions of B decays to D{sub s}{sup (*}}D{sup (*)} modes, we find the Cabibbo-Kobayashi-Maskawa phase {gamma} is favored to lie in the range (0.07-2.77) radians (with a +0 or +{pi} radians ambiguity) at 68% confidence level.« less

Two-Phase Flow in High-Heat-Flux Micro-Channel Heat Sink for Refrigeration Cooling Applications. Part 2: Low Temperature Hybrid Micro-Channel/Micro-Jet Impingement Cooling

DTIC Science & Technology

2008-09-01

TWO-PHASE FLOW IN HIGH-HEAT-FLUX MICRO-CHANNEL HEAT SINK FOR REFRIGERATION COOLING APPLICATIONS (Contract No. N00014-05-1-0408) by Issam Mudawar ...Refrigeration Cooling Applications 5b. GRANT NUMBER N00014-04-1-0408 5c. PROGRAM ELEMENT NUMBER NA 6. AUTHOR(S) 5d. PROJECT NUMBER Mudawar , Issam NA...ABSTRACT OF Mudawar , Issam PAGES U U U UU 465 19b. TELEPHONE NUMBER (Include area code) 765-494-5705 Standard Form 298 (Rev. 8/98) Prescribed by ANSI Std

10 CFR Appendix B to Subpart D of... - Categorical Exclusions Applicable to Specific Agency Actions

Code of Federal Regulations, 2014 CFR

2014-01-01

... 10 Energy 4 2014-01-01 2014-01-01 false Categorical Exclusions Applicable to Specific Agency Actions B Appendix B to Subpart D of Part 1021 Energy DEPARTMENT OF ENERGY (GENERAL PROVISIONS) NATIONAL ENVIRONMENTAL POLICY ACT IMPLEMENTING PROCEDURES Typical Classes of Actions Pt. 1021, Subpt. D, App. B Appendix B to Subpart D of Part 1021...

10 CFR Appendix B to Subpart D of... - Categorical Exclusions Applicable to Specific Agency Actions

Code of Federal Regulations, 2012 CFR

2012-01-01

... 10 Energy 4 2012-01-01 2012-01-01 false Categorical Exclusions Applicable to Specific Agency Actions B Appendix B to Subpart D of Part 1021 Energy DEPARTMENT OF ENERGY (GENERAL PROVISIONS) NATIONAL ENVIRONMENTAL POLICY ACT IMPLEMENTING PROCEDURES Typical Classes of Actions Pt. 1021, Subpt. D, App. B Appendix B to Subpart D of Part 1021...

10 CFR Appendix B to Subpart D of... - Categorical Exclusions Applicable to Specific Agency Actions

Code of Federal Regulations, 2013 CFR

2013-01-01

... 10 Energy 4 2013-01-01 2013-01-01 false Categorical Exclusions Applicable to Specific Agency Actions B Appendix B to Subpart D of Part 1021 Energy DEPARTMENT OF ENERGY (GENERAL PROVISIONS) NATIONAL ENVIRONMENTAL POLICY ACT IMPLEMENTING PROCEDURES Typical Classes of Actions Pt. 1021, Subpt. D, App. B Appendix B to Subpart D of Part 1021...

Genome-Enabled Molecular Tools for Reductive Dehalogenation

DTIC Science & Technology

2011-11-01

Genome-Enabled Molecular Tools for Reductive Dehalogenation - A Shift in Paradigm for Bioremediation - Alfred M. Spormann Departments of Chemical...Genome-Enabled Molecular Tools for Reductive Dehalogenation 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d...Applications Technical Session No. 3D C-77 GENOME-ENABLED MOLECULAR TOOLS FOR REDUCTIVE DEHALOGENATION PROFESSOR ALFRED SPORMANN Stanford

Effectiveness of a Treatment Involving Soft Tissue Techniques and/or Neural Mobilization Techniques in the Management of Tension-Type Headache: A Randomized Controlled Trial.

PubMed

Ferragut-Garcías, Alejandro; Plaza-Manzano, Gustavo; Rodríguez-Blanco, Cleofás; Velasco-Roldán, Olga; Pecos-Martín, Daniel; Oliva-Pascual-Vaca, Jesús; Llabrés-Bennasar, Bartomeu; Oliva-Pascual-Vaca, Ángel

2017-02-01

To evaluate the effects of a protocol involving soft tissue techniques and/or neural mobilization techniques in the management of patients with frequent episodic tension-type headache (FETTH) and those with chronic tension-type headache (CTTH). Randomized, double-blind, placebo-controlled before and after trial. Rehabilitation area of the local hospital and a private physiotherapy center. Patients (N=97; 78 women, 19 men) diagnosed with FETTH or CTTH were randomly assigned to groups A, B, C, or D. (A) Placebo superficial massage; (B) soft tissue techniques; (C) neural mobilization techniques; (D) a combination of soft tissue and neural mobilization techniques. The pressure pain threshold (PPT) in the temporal muscles (points 1 and 2) and supraorbital region (point 3), the frequency and maximal intensity of pain crisis, and the score in the Headache Impact Test-6 (HIT-6) were evaluated. All variables were assessed before the intervention, at the end of the intervention, and 15 and 30 days after the intervention. Groups B, C, and D had an increase in PPT and a reduction in frequency, maximal intensity, and HIT-6 values in all time points after the intervention as compared with baseline and group A (P<.001 for all cases). Group D had the highest PPT values and the lowest frequency and HIT-6 values after the intervention. The application of soft tissue and neural mobilization techniques to patients with FETTH or CTTH induces significant changes in PPT, the characteristics of pain crisis, and its effect on activities of daily living as compared with the application of these techniques as isolated interventions. Copyright © 2016 American Congress of Rehabilitation Medicine. Published by Elsevier Inc. All rights reserved.

Advanced Tactical Booster Technologies: Applications for Long-Range Rocket Systems

DTIC Science & Technology

2016-09-07

Applications for Long-Range Rocket Systems 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Matthew McKinna, Jason Mossman 5d...technology advantages currently under development for tactical rocket motors which have direct application to land-based long-range rocket systems...increased rocket payload capacity, improved rocket range or increased rocket loadout from the volumetrically constrained environment of a land-based

Application of in vitro bioaccessibility and bioavailability methods for calcium, carotenoids, folate, iron, magnesium, polyphenols, zinc and vitamins B6, B12, D, and E

USDA-ARS?s Scientific Manuscript database

A review of in vitro bioaccessibility and bioavailability methods for polyphenols and selected nutrients is presented. The review focuses on in vitro solubility, dialyzability, the dynamic gastrointestinal model (TIM), and Caco-2 cell models, the latter primarily for uptake and transport, and a disc...

77 FR 72363 - National Institute Of Nursing Research; Notice of Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-05

... Nursing Research; Notice of Meeting Pursuant to section 10(d) of the Federal Advisory Committee Act, as... Research. The meeting will be open to the public as indicated below, with attendance limited to space... 552b(c)(4) and 552b(c)(6), Title 5 U.S.C., as amended. The grant applications and the discussions could...

75 FR 20853 - National Institute of Nursing Research; Notice of Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-21

... Nursing Research; Notice of Meeting Pursuant to section 10(d) of the Federal Advisory Committee Act, as... Research. The meeting will be open to the public as indicated below, with attendance limited to space... 552b(c)(4) and 552b(c)(6), Title 5 U.S.C., as amended. The grant applications and the discussions could...

78 FR 78983 - Office of the Director, National Institutes of Health; Notice of Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-27

... in sections 552b(c)(4), and 552b(c)(6), Title 5 U.S.C., as amended. The grant applications and the... 20892. Contact Person: Franziska Grieder, DVM, Ph.D., Executive Secretary, Director, Office of Research... example, a government-issued photo ID, driver's license, or passport) and to state the purpose of their...

75 FR 13561 - National Institute of Dental & Craniofacial Research; Notice of Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-22

... & Craniofacial Research; Notice of Meeting Pursuant to section 10(d) of the Federal Advisory Committee Act, as... Craniofacial Research Council. The meeting will be open to the public as indicated below, with attendance... set forth in sections 552b(c)(4) and 552b(c)(6), Title 5 U.S.C., as amended. The grant applications...

76 FR 76169 - National Institute of Nursing Research; Notice of Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-06

... Nursing Research; Notice of Meeting Pursuant to section 10(d) of the Federal Advisory Committee Act, as... Research. The meeting will be open to the public as indicated below, with attendance limited to space... 552b(c)(4) and 552b(c)(6), Title 5 U.S.C., as amended. The grant applications and/or contract proposals...

78 FR 75358 - National Institute of Nursing Research; Notice of Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-11

... Nursing Research; Notice of Meeting Pursuant to section 10(d) of the Federal Advisory Committee Act, as... Research. The meeting will be open to the public as indicated below, with attendance limited to space... 552b(c)(4) and 552b(c)(6), Title 5 U.S.C., as amended. The grant applications and/or contract proposals...

77 FR 45645 - National Institute of Nursing Research; Notice of Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2012-08-01

... Nursing Research; Notice of Meeting Pursuant to section 10(d) of the Federal Advisory Committee Act, as... Research. The meeting will be open to the public as indicated below, with attendance limited to space... 552b(c)(4) and 552b(c)(6), Title 5 U.S.C., as amended. The grant applications and the discussions could...

Tri-Lab Co-Design Milestone: In-Depth Performance Portability Analysis of Improved Integrated Codes on Advanced Architecture.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hoekstra, Robert J.; Hammond, Simon David; Richards, David

2017-09-01

This milestone is a tri-lab deliverable supporting ongoing Co-Design efforts impacting applications in the Integrated Codes (IC) program element Advanced Technology Development and Mitigation (ATDM) program element. In FY14, the trilabs looked at porting proxy application to technologies of interest for ATS procurements. In FY15, a milestone was completed evaluating proxy applications in multiple programming models and in FY16, a milestone was completed focusing on the migration of lessons learned back into production code development. This year, the co-design milestone focuses on extracting the knowledge gained and/or code revisions back into production applications.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Temple, Brian Allen; Armstrong, Jerawan Chudoung

This document is a mid-year report on a deliverable for the PYTHON Radiography Analysis Tool (PyRAT) for project LANL12-RS-107J in FY15. The deliverable is deliverable number 2 in the work package and is titled “Add the ability to read in more types of image file formats in PyRAT”. Right now PyRAT can only read in uncompressed TIF files (tiff files). It is planned to expand the file formats that can be read by PyRAT, making it easier to use in more situations. A summary of the file formats added include jpeg, jpg, png and formatted ASCII files.

Transuranic Waste Program Framework Agreement - December Deliverable July 2012

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jones, Patricia

Framework agreement deliverables are: (1) 'DOE/NNSA commits to complete removal of all non-cemented above-ground EM Legacy TRU and newly generated TRU currently-stored at Area G as of October 1, 2011, by no later than June 30, 2014. This inventory of above-ground TRU is defined as 3706 cubic meters of material.' (2) 'DOE commits to the complete removal of all newly generated TRU received in Area G during FY 2012 and 2013 by no later than December 31, 2014.' (3) 'Based on projected funding profiles, DOE/NNSA will develop by December 31, 2012, a schedule, including pacing milestones, for disposition of themore » below-ground TRU requiring retrieval at Area G.' Objectives are to: (1) restore the 'Core Team' to develop the December, 2012 deliverable; (2) obtain agreement on the strategy for below ground water disposition; and (3) establish timeline for completion of the deliverable. Below Grade Waste Strategy is to: (1) Perform an evaluation on below grade waste currently considered retrievable TRU; (2) Only commit to retrieve waste that must be retrieved; (3) Develop the Deliverable including Pacing Milestones based on planned commitments; (4) Align all Regulatory Documents for Consistency; and (5) answer these 3 primary questions, is the waste TRU; is the waste retrievable, can retrieval cause more harm than benefit?« less

Feasibility of Nanoparticle-Guided Radiation Therapy (NGRT) Using a Conventional CT Scanner

DTIC Science & Technology

2010-10-01

deliverability of plan on CT scanner 2c. Calibrate dosimeters ( TLDs ) in phantom material 2d. Deliver dose distribution to phantom with TLDs in...phantom (SOW 2a). Next, small thermoluminescent dosimeters ( TLDs ) are placed within the tumor cavity. The TLDs are irradiated both with and without...nuclear data files. Electron interaction data is taken from the RSICC-EL03 library. The tumor volume was simulated as a small cavity containing

Comparison of Capsular Genes of Streptococcus pneumoniae Serotype 6A, 6B, 6C, and 6D Isolates▿

PubMed Central

Song, Jae-Hoon; Baek, Jin Yang; Ko, Kwan Soo

2011-01-01

Recently, Streptococcus pneumoniae serotypes 6C and 6D have been identified. It is thought that they emerged by the replacement of wciNβ in the capsular loci of serotypes 6A and 6B, respectively. However, their evolution has not been unveiled yet. To investigate the evolution of four serotypes of S. pneumoniae serogroup 6, four genes of the capsular polysaccharide synthesis (cps) locus, wchA, wciN, wciO, and wciP, of isolates of S. pneumoniae serotypes 6A, 6B, 6C, and 6D were sequenced. Multilocus sequence typing (MLST) was performed to investigate their genetic backgrounds. The wchA gene of serotype 6C and 6D isolates was distinct from that of serotype 6A and 6B isolates, which may suggest cotransfer of wchA with wciNβ. Otherwise, serotypes 6C and 6D displayed different genetic backgrounds from serotypes 6A and 6B, which was suggested by MLST analysis. In addition, serotype 6C isolates showed distinct wciP polymorphisms from other serotypes, which also indicated that serotype 6C had not recently originated from serotype 6A. Although serotype 6D shared the same amino acid polymorphisms of wciO with serotype 6B, wciP of serotype 6D differed from that of serotype 6B. The data indicate the implausibility of the scenario of a recent emergence of the cps locus of serotype 6D by genetic recombination between serotypes 6B and 6C. In addition, five serotype 6A and 6B isolates (6X group) displayed cps loci distinct from those of other isolates. The cps locus homogeneity and similar sequence types in MLST analysis suggest that most of the 6X group of isolates originated from the same ancestor and that the entire cps locus might have recently been transferred from an unknown origin. Serotype 6B isolates showed two or more cps locus subtypes, indicating a recombination-mediated mosaic structure of the cps locus of serotype 6B. The collective data favor the emergence of cps loci of serotypes 6A, 6B, 6C, and 6D by complicated recombination. PMID:21411593

Monolithic control components for high power mm-waves

NASA Astrophysics Data System (ADS)

Armstrong, A.; Goodrich, J.; Moroney, W.; Wheeler, D.

1985-09-01

Monolithic PIN diode arrays are shown to provide significant advances in switching ratios, bandwidth, and high-power capability for millimeter control applications The PIN diodes are arranged in a series/parallel configuration and form an electronically controlled window for switching RF power by applying DC voltage. At Ka band, an SPST switch using the window array (WINAR) design typically has 0.6 dB insertion loss and 22 dB isolation over the 26.5 to 40.0 GHz band. The switch has over 500 W peak power and 25 W average power capability.

Applications of Piezoelectric and Pyroelectric Thin Films: Opportunities for Langmuir-Blodgett Technology.

DTIC Science & Technology

1984-12-31

LII IH"L 5 B 1.4 1111.6 MICROCOPY RESOLUTION TEST CHART SECURITY CLASSIFICATION OF THIS PAGE (MS’ien Dare Itere d) RED DSTUC ONS REPORT ...DOCUMENTATION PAGE BEFORE COMPLETIG FORM R NUMER . GOVT ACCESSION NO 5. RECIPIENT’S CATALOG iUMBER • TR-09 4. TITLE ( nd Subttle) S. TYPE OF REPORT A PERIOD...COVERELs Applications of Piezoelectric and Pyroelectric Technical Report -Interim Thin Films: Opportunities for Langmuir-Blodgett Technology 6. PERFORMING

Large signal design - Performance and simulation of a 3 W C-band GaAs power MMIC

NASA Astrophysics Data System (ADS)

White, Paul M.; Hendrickson, Mary A.; Chang, Wayne H.; Curtice, Walter R.

1990-04-01

This paper describes a C-band GaAs power MMIC amplifier that achieved a gain of 17 dB and 1 dB compressed CW power output of 34 dBm across a 4.5-6.25-GHz frequency range, without design iteration. The first-pass design success was achieved due to the application of a harmonic balance simulator to define the optimum output load, using a large-signal FET model determined statistically on a well controlled foundry-ready process line. The measured performance was close to that predicted by a full harmonic balance circuit analysis.

Broadband athermal waveguides and devices for datacom and telecom applications

NASA Astrophysics Data System (ADS)

He, Liuqing; Guo, Yuhao; Han, Zhaohong; Wada, Kazumi; Kimerling, Lionel C.; Michel, Jurgen; Agarwal, Anuradha M.; Li, Guifang; Zhang, Lin

2018-02-01

The high temperature sensitivity of silicon material limits the applications of silicon-based micro-ring resonators in integrated photonics. To realize a low but broadband temperature-dependence-wavelength-shift (TDWS) micro-ring resonator, designing a broadband athermal waveguide becomes a significant task. In this work, we propose a broadband athermal waveguide which shows a low effective thermos-optical coefficient (TOC) of +/-1×10-6/K at 1400 nm to 1700 nm. The proposed waveguide shows low-loss performance of 0.01 dB/cm and stable broadband-athermal ability when it's applied in micro-ring resonators, and the optical loss of micro-ring resonator with a radius of 100 μm using this waveguide is 0.02 dB/cm.

Urban expansion of major cities in the US Great Plains from 2000 to 2009 using scatterometer data

NASA Astrophysics Data System (ADS)

Nguyen, L. H.; Nghiem, S. V.; Henebry, G. M.

2015-12-01

A long-term metric of urban landscape changes provide valuable information for many fundamental studies and applications. Here we studied expansion of the nine largest metropolitan statistical areas (MSA) in the Great Plains from 2000 to 2009 period using QuikSCAT backscatter data processed with the Dense Sampling Method (DSM). A 5x5 Gaussian Kernel Smoothing (with sigma=1) was applied to reduce noise in DSM backscatter images, which have a nominal spatial posting of 1 km. The outputs were then converted into vector files and coupled with the percent impervious surface area (ISA) data from the 2001 and 2011 National Land Cover Datasets to show changes in urban extent using two independent sources. The results demonstrate the capability of DSM scatterometer data to delineate urban extent and change. For instance, the Dallas - Fort Worth (DFW) MSA was separated into three sub-regions based on backscatter (cf. figure). The urban core area is identified by large commercial and industrial structures correspond to a high backscatter center greater than -6 dB. The urban built-up area consisting of smaller buildings falls within the -6 dB and -8 dB contours. Backscatter of the urban edge, where residential and other land uses are mixed, falls within the -8 dB and -10 dB contours. From 2000 to 2009, total urban area in DFW increased from 3484 to 5066 square kilometers, according to the filtered scatterometer data. The change in ISA between 2001 and 2011 within the -8 to -10 dB contour was 101 square kilometers, of which 73% occurred in the northern half of the DFW MSA. The Mann-Kendall trend test applied to the area time series indicates expanding spatial trends in every sub-region. Most changes occurred along the northern suburban edge. The distance between the 2000 and 2009 -10 dB contours ranged from 1.5 to 14.6 km with an average of 6 km and a coefficient of variation of 48%. We will present results for the other eight MSA from Houston, TX to Des Moines, IA.

A 0.02% THD and 80 dB PSRR filterless class D amplifier with direct lithium battery hookup in mobile application

NASA Astrophysics Data System (ADS)

Zheng, Hao; Zhu, Zhangming; Ma, Rui

2017-07-01

This paper presents a fully integrated CMOS filterless class D amplifier that can directly hook up lithium battery in mobile application The proposed amplifier embodies a 2-order feedback path architecture instead of direct feedback of output to input of the integrator to decrease the high frequency intermodulation distortion associated with direct feedback and eliminate the integrator input common mode disturbance from the output in ternary modulation. The prototype class D amplifier realized in 0.35 μm digital technology achieves a THD+N of 0.02% when delivering 400 mW to an 8 {{Ω }} load from {V}{DD}=3.6 {{V}}. The PSRR of the prototype class D amplifier is 80 dB at 217 Hz. Furthermore a filterless method that can eliminate the external LC filter is employed which offers great advantages of saving PCB space and lowering system cost. In addition the prototype class D amplifier can operate in large voltage range with V DD range from 2.5 to 4.2 V in mobile application. The total area of the amplifier is 1.7 mm2. Project supported by the National Natural Science Foundation of China (Nos. 61234002, 61322405, 61306044).

Handheld, rapidly switchable, anterior/posterior segment swept source optical coherence tomography probe

PubMed Central

Nankivil, Derek; Waterman, Gar; LaRocca, Francesco; Keller, Brenton; Kuo, Anthony N.; Izatt, Joseph A.

2015-01-01

We describe the first handheld, swept source optical coherence tomography (SSOCT) system capable of imaging both the anterior and posterior segments of the eye in rapid succession. A single 2D microelectromechanical systems (MEMS) scanner was utilized for both imaging modes, and the optical paths for each imaging mode were optimized for their respective application using a combination of commercial and custom optics. The system has a working distance of 26.1 mm and a measured axial resolution of 8 μm (in air). In posterior segment mode, the design has a lateral resolution of 9 μm, 7.4 mm imaging depth range (in air), 4.9 mm 6dB fall-off range (in air), and peak sensitivity of 103 dB over a 22° field of view (FOV). In anterior segment mode, the design has a lateral resolution of 24 μm, imaging depth range of 7.4 mm (in air), 6dB fall-off range of 4.5 mm (in air), depth-of-focus of 3.6 mm, and a peak sensitivity of 99 dB over a 17.5 mm FOV. In addition, the probe includes a wide-field iris imaging system to simplify alignment. A fold mirror assembly actuated by a bi-stable rotary solenoid was used to switch between anterior and posterior segment imaging modes, and a miniature motorized translation stage was used to adjust the objective lens position to correct for patient refraction between −12.6 and + 9.9 D. The entire probe weighs less than 630 g with a form factor of 20.3 x 9.5 x 8.8 cm. Healthy volunteers were imaged to illustrate imaging performance. PMID:26601014

30/20 GHz spacecraft GaAs FET solid state transmitter for trunking and customer-premise-service application

NASA Technical Reports Server (NTRS)

Saunier, P.; Nelson, S.

1983-01-01

Sixteen 30 dB 0.5 W amplifier modules were combined to satisfy the requirement for a graceful degradation. If one module fails, the output power drops by only 0.43 dB. Also, by incorporating all the gain stages within the combiner the overall combining efficiency is maximized. A 16 way waveguide divider combiner was developed to minimize the insertion loss associated with such a large corporate feed structure. Tests showed that the 16 way insertion loss was less than 0.5 dB. To minimize loss, a direct transition from waveguide to microstrip, using a finline on duroid substrate, was developed. The FETs fabricated on MBE grown material, demonstrated superior performances. For example, a 600 micrometer device was capable of 320 mW output power with 5 dB gain and 26.6% efficiency at 21 GHz. The 16 module amplifier gave 8.95 W saturated output power with 30 dB gain. The overall efficiency was 9%. The 3 dB bandwidth was 2.5 GHz. At 17.7 GHz the amplifier had 5 W output power and at 20.2 GHz it still had 4.4 W.

76 FR 65769 - Application of Friendship Airways, Inc. d/b/a Yellow Air Taxi for Commuter Authority

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-24

... DEPARTMENT OF TRANSPORTATION Office of the Secretary Application of Friendship Airways, Inc. d/b/a Yellow Air Taxi for Commuter Authority AGENCY: Department of Transportation. ACTION: Notice of Order to... issued to Friendship Airways, Inc. d/b/a Yellow Air Taxi and deny its application to resume commuter...

Guidance for improving foundation layers to increase pavement performance on local roads.

DOT National Transportation Integrated Search

2014-11-01

This document is the second of two deliverables for the project Optimizing Pavement Base, Subbase, and Subgrade Layers : for Cost and Performance on Local Roads (TR-640). The first deliverable is the 454-page Final Field Data Report. The field : data...

7 CFR Exhibit D to Subpart B of... - Designated Counties for Housing Application Packaging Grants

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 13 2010-01-01 2009-01-01 true Designated Counties for Housing Application Packaging... Application Packaging Grants Pt. 1944, Subpt. B, Exh. D Exhibit D to Subpart B of Part 1944—Designated Counties for Housing Application Packaging Grants ER25my05.036 ER25my05.037 ER25my05.038 ER25my05.039 [70...

Modularity: An Application of General Systems Theory to Military Force Development

DTIC Science & Technology

2005-01-01

1999). Context, modularity, and the cultural constitution of development. In P. Lloyd & C. Fernyhough (Eds.), Lev Vygotsky : Critical assessments...of General Systems Theory to Military Force Development 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT...Prescribed by ANSI Std Z39-18 MODULARITY: AN APPLICATION OF GENERAL SYSTEMS THEORY TO MILITARY FORCE DEVELOPMENT 279 R SEARCH MODULARITY: AN APPLICATION OF

Dynamics and Control of Non-Smooth Systems with Applications to Supercavitating Vehicles

DTIC Science & Technology

2011-01-01

ABSTRACT Title of dissertation: Dynamics and Control of Non-Smooth Systems with Applications to Supercavitating Vehicles Vincent Nguyen, Doctor of...relates to the dynamics of non-smooth vehicle systems, and in particular, supercavitating vehicles. These high-speed under- water vehicles are...Applications to Supercavitating Vehicles 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT NUMBER 5e. TASK

The President Has No Clothes: The Case for Broader Application of Red Teaming within Homeland Security

DTIC Science & Technology

2010-06-01

CLOTHES: THE CASE FOR BROADER APPLICATION OF RED TEAMING WITHIN HOMELAND SECURITY by A. Bentley Nettles June 2010 Thesis Advisor...Red Teaming Within Homeland Security 6. AUTHOR(S) A. Bentley Nettles 5. FUNDING NUMBERS 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES...APPLICATION OF RED TEAMING WITHIN HOMELAND SECURITY A. Bentley Nettles Colonel, United States Army B.A., Texas A&M University, 1985 J.D. South

Controlling cull ohia trees by injecting herbicides

Treesearch

Stanley B. Carpenter

1966-01-01

Ohia trees less than 6 inches d .b.h. on the island of Hawaii were killed by injection of undiluted 2,4.S-T ester. This chemical was less effective on larger trees. Injections applied in September and January were more effective than the May applications. Injections of 2,4-D were relatively ineffective, any season of the year, even for small trees. Tardon 22K proved...

On the Role of Dimensionless Elastic Fracture Mechanics.

DTIC Science & Technology

1985-07-03

34.’ . . . .- . . - . . . - ... - . .. . . . . . -8-.V 6. B.M. Wundt , "A Unified Interpretation of Room Temperature Strength of Notched...207s (1948). D.H. Winne and B.M. Wundt , Application of the Griffith-Irwin theory of crack propagation to the bursting behavior of disks, including... Wundt , A unified interpretation of room-temperature strength of notched specimens as influenced by their size. Metals Engng. Conf., ASME Paper No

TU-AB-201-01: A Comprehensive Planning Comparison Study Between a Novel Direction Modulated Brachytherapy Tandem Applicator and Conventional T&R Applicator for Image Guided Cervical Cancer Brachytherapy

DOE Office of Scientific and Technical Information (OSTI.GOV)

Han, D; Liu, Z; University of California, San Diego, La Jolla, CA

2015-06-15

Purpose: To demonstrate that utilization of a novel, intensity modulation capable, direction modulated brachytherapy (DMBT) tandem applicator can improve plan quality compared with conventional T&R applicator during an image guided cervical cancer brachytherapy. Methods: 45 cervical cancer patients treated with PDR brachytherapy were reviewed. Of them, a) 27 were treated using T&R only, b) 9 were treated using T&R with needles attached to the ring, and c) the remaining 9 were treated using T&R with needles attached to the ring (AN) as well as additional free-hand-loaded needles (FN). The DMBT tandem design has 6 peripheral holes of 1.3-mm diameter, groovedmore » along a nonmagnetic tungsten alloy rod, enclosed in a plastic sheath with total 6.0-mm diameter. An in-house-coded inverse planning system was used for planning DMBT and T&R cases. All typical clinical constraints including OAR dose limits, dwell times, and loading patterns were respected. For the DMBT and T&R applicators, the plans were optimized with the same conventional ring in place, but repeatedly planned with and without AN/FN needles. All generated plans were normalized to the same D90 of the clinically treated plans. Results: For the plans in category a), DMBT generally outperformed T&R with average reduction in D2cc of −2.39%, −5.21%, and −2.69% for bladder, rectum, and sigmoid, respectively. For the plans in category b) and c), DMBT generally outperformed T&R if the same needles in AN/FN were utilized in both cases with average reduction in D2cc of −1.82%, −3.40%, and −6.04%, respectively. For the cases where the needles were not utilized for both applicators, an average D2cc reduction of −7.45%, −7.61%, and 17.47% were observed, respectively. Conclusions: Under the same clinical conditions, with/without needles, the DMBT applicator tends to generate more favorable plans compared with the conventional T&R applicator, and hence, is a promising technology.« less

Portable Dynamic Pressure Calibrator

NASA Technical Reports Server (NTRS)

Wright, Morgan S.; Maynard, Everett (Technical Monitor)

1996-01-01

A portable, dynamic pressure calibrator was fabricated for use on wind tunnel models at NASA-Ames Research Center. The calibrator generates sine wave pressures at levels up to 1 PSIG P-P(168dB) at frequencies from 10Hz to 6KHz and .5 PSIG P.P (162dB) at frequencies from 6KHz to 20KHz. The calibrator consists of two units connected by a single cable. The handheld unit contains a pressure transducer, speaker, and deadman switch. This unit allows application of dynamic pressure to transducers/ports on installed wind tunnel models. The base unit contains all of power supplies, controls and displays. This unit allows amplitude and frequency to be set and verified at a safe location off of the model.

Preliminary Evaluation of GAOFEN-3 Polarimetric and Radiometric Accuracy by Corner Reflectors in Inner Mongolia

NASA Astrophysics Data System (ADS)

Shi, L.; Ding, X.; Li, P.; Yang, J.; Zhao, L.; Yang, L.; Chang, Y.; Yan, L.

2018-04-01

On August 10, 2016, China launched its first C-band full polarimetric radar satellite, named Gaofen-3 (GF-3), for urban and agriculture monitoring, landslide detection, ocean applications, etc. According to the design specification, GF-3 is expected to work at -35 dB crosstalk and 0.5 dB channel imbalance, with less than 10 degree error. The absolute radiometric bias is expected to be less than 1.5 dB in a single scene and 2.0 dB when operating for a long time. To complete the calibration and evaluation, the Institute of Electronics, Chinese Academy Sciences (IECAS) built a test site at Inner Mongolia, and deployed active reflectors (ARs) and trihedral corner reflectors (CRs) to solve and evaluate the hardware distortion. To the best of the authors' knowledge, the product accuracy of GF-3 has not been comprehensively evaluated in any open publication. The remote sensing community urgently requires a detailed report about the product accuracy and stability, before any subsequent application. From June to August of 2017, IECAS begun its second round ground campaign and deployed 10 CRs to evaluate product distortions. In this paper, we exploit Inner Mongolia CRs to investigate polarimetric and radiometric accuracy of QPSI I Stripmap. Although some CRs found fall into AR side lobe, the rest CRs enable us to preliminarily evaluate the accuracy of some special imaging beams. In the experimental part, the image of July 6, 2017 was checked by 5 trihedral CRs and the integration estimation method demonstrated the crosstalk varying from -42.65 to -32.74 dB, and the channel imbalance varying from -0.21 to 0.47 with phase error from -2.4 to 0.2 degree. Comparing with the theoretical radar cross-section of 1.235 m trihedral CR, i.e. 35 dB, the radiometric error varies about 0.20 ± 0.29 dB in HH channel and 0.40 ± 0.20 dB in VV channel.

The Creative Deliverable: A Short Communication

ERIC Educational Resources Information Center

Hartel, Jenna; Noone, Rebecca; Oh, Christie

2017-01-01

This paper encourages educators in library and information science (LIS) to adopt the "creative deliverable," that is, an assignment that gives students the freedom to display their understanding of course material in an almost unrestricted range of alternative formats and genres, while retaining some key features of traditional…

Glyphosate in the general population and in applicators: a critical review of studies on exposures.

PubMed

Solomon, Keith R

2016-09-01

The recent classification of glyphosate as a probable human carcinogen by the International Agency for Research on Cancer (IARC) was arrived at without a detailed assessment of exposure. Glyphosate is widely used as an herbicide, which might result in exposures of the general public and applicators. Exposures were estimated from information in the open literature and unpublished reports provided by Monsanto Company. Based on the maximum measured concentration in air, an exposure dose of 1.04 × 10  -   6  mg/kg body mass (b.m.)/d was estimated. Assuming consumption of surface water without treatment, the 90th centile measured concentration would result in a consumed dose of 2.25 × 10  -   5  mg/kg b.m./d. Estimates by the Food and Agriculture Organization of the United Nations (FAO) of consumed doses in food provided a median exposure of 0.005 mg/kg b.m./d (range 0.002-0.013). Based on tolerance levels, the conservative estimate by the US Environmental Protection Agency (US EPA) for exposure of the general population via food and water was 0.088 mg/kg b.m./d (range 0.058-0.23). For applicators, 90th centiles for systemic exposures based on biomonitoring and dosimetry (normalized for penetration through the skin) were 0.0014 and 0.021 mg/kg b.m./d, respectively. All of these exposures are less than the reference dose and the acceptable daily intakes proposed by several regulatory agencies, thus supporting a conclusion that even for these highly exposed populations the exposures were within regulatory limits.

Design and analysis of high gain and low noise figure CMOS low noise amplifier for Q-band nano-sensor application

NASA Astrophysics Data System (ADS)

Suganthi, K.; Malarvizhi, S.

2018-03-01

A high gain, low power, low Noise figure (NF) and wide band of milli-meter Wave (mmW) circuits design at 50 GHz are used for Radio Frequency (RF) front end. The fundamental necessity of a receiver front-end includes perfect output and input impedance matching and port-to-port isolation with high gain and low noise over the entire band of interest. In this paper, a design of Cascade-Cascode CMOS LNA circuit at 50 GHz for Q-band application is proposed. The design of Low noise amplifier at 50 GHz using Agilent ADS tool with microstrip lines which provides simplicity in fabrication and less chip area. The low off-leakage current Ioff can be maintained with high K-dielectrics CMOS structure. Nano-scale electronics can be achieved with increased robustness. The design has overall gain of 11.091 dB and noise figure of 2.673 dB for the Q-band of 48.3 GHz to 51.3 GHz. Impedance matching is done by T matching network and the obtained input and output reflection coefficients are S11 = <-10 dB and S22 = <-10 dB. Compared to Silicon (Si) material, Wide Band Gap semiconductor materials used attains higher junction temperatures which is well matched to ceramics used in packaging technology, the protection and reliability also can be achieved with the electronic packaging. The reverse transmission coefficient S21 is less than -21 dB has shown that LNA has better isolation between input and output, Stability factor greater than 1 and Power is also optimized in this design. Layout is designed, power gain of 4.6 dB is achieved and area is optimized which is nearly equal to 502 740 μm2. The observed results show that the proposed Cascade-Cascode LNA design can find its suitability in future milli-meter Wave Radar application.

Low-loss Kagome hollow-core fibers operating from the near- to the mid-IR.

PubMed

Wheeler, N V; Bradley, T D; Hayes, J R; Gouveia, M A; Liang, S; Chen, Y; Sandoghchi, S R; Abokhamis Mousavi, S M; Poletti, F; Petrovich, M N; Richardson, D J

2017-07-01

We report the fabrication and characterization of Kagome hollow-core antiresonant fibers, which combine low attenuation (as measured at ∼30  cm bend diameter) with a wide operating bandwidth and high modal purity. Record low attenuation values are reported: 12.3 dB/km, 13.9 dB/km, and 9.6 dB/km in three different fibers optimized for operation at 1 μm, 1.55 μm, and 2.5 μm, respectively. These fibers are excellent candidates for ultra-high power delivery at key laser wavelengths including 1.064 μm and 2.94 μm, as well as for applications in gas-based sensing and nonlinear optics.

THz Sources for Space

NASA Technical Reports Server (NTRS)

Siegel, Peter H.; Ward, John; Maiwald, Frank; Mehdi, Imran

2007-01-01

Terahertz is the primary frequency for line and continuum radiation from cool (5-100K) gas (atoms and molecules) and dust. This viewgraph presentation reviews the reasons for the interest in Terahertz Space Applications; the Terahertz Space Missions: in the past, present and planned for the future, Terahertz source requirements and examples of some JPL instruments; and a case study for a flight deliverable: THz Local Oscillators for ESA s Herschel Space Telescope

Development and Application of Decision Aid for Tactical Control of Battlefield Operations: Bibliographic Sort of the Decision Aiding Literature

DTIC Science & Technology

1973-12-01

THEORY GAML THE’RY GROUP PROb SQL= U tIC PMLTRIC3b 63 C.LARKSON G a DEC MAK IN SMALL GROUPS A SIM STUDY bLHt SCI 6t0 13 2081 bRUNER J b STUDIES IN...MAK IN SMALL GROUPS A SIN STUDY : BLH 5(1 6d 13 2861 DODSON j 0 AS SIN RES FACILITYz SIN SYS DGN FOR TE AkCRL 111 PRI9I4• FLEEING R ASKS PROC.CONFLICTING...POU315IC HF. 66 MAR 7-1 SHURL ( H NNUAtCENTER FOR COMP BASED BEH STUDIES UCLA SEMIA NTIS-AD 731059 713 CLARKSON b DEC MAK IN SMALL GROUPS A SIM STUDY

50 MHz-10 GHz low-power resistive feedback current-reuse mixer with inductive peaking for cognitive radio receiver.

PubMed

Vitee, Nandini; Ramiah, Harikrishnan; Chong, Wei-Keat; Tan, Gim-Heng; Kanesan, Jeevan; Reza, Ahmed Wasif

2014-01-01

A low-power wideband mixer is designed and implemented in 0.13 µm standard CMOS technology based on resistive feedback current-reuse (RFCR) configuration for the application of cognitive radio receiver. The proposed RFCR architecture incorporates an inductive peaking technique to compensate for gain roll-off at high frequency while enhancing the bandwidth. A complementary current-reuse technique is used between transconductance and IF stages to boost the conversion gain without additional power consumption by reusing the DC bias current of the LO stage. This downconversion double-balanced mixer exhibits a high and flat conversion gain (CG) of 14.9 ± 1.4 dB and a noise figure (NF) better than 12.8 dB. The maximum input 1-dB compression point (P1dB) and maximum input third-order intercept point (IIP3) are -13.6 dBm and -4.5 dBm, respectively, over the desired frequency ranging from 50 MHz to 10 GHz. The proposed circuit operates down to a supply headroom of 1 V with a low-power consumption of 3.5 mW.

Silver deposited carboxymethyl chitosan-grafted magnetic nanoparticles as dual action deliverable antimicrobial materials.

PubMed

Vo, Duc-Thang; Sabrina, Sabrina; Lee, Cheng-Kang

2017-04-01

Carboxymethyl chitosan (CMCS) was known to have a much better antimicrobial activity than chitosan due to the increased cationic -NH 3 + groups resulted from the intra- and intermolecular interactions between the carboxyl and amino groups. CMCS was grafted onto the surface of silica coated magnetic nanoparticles (MNPs) to obtain magnetically retrievable and deliverable antimicrobial nanoparticles (MNPs@CMCS). The presence of carboxylate groups in CMCS not only enhanced antimicrobial activity but also enabled Ag ions chelating ability to induce the in situ formation of Ag nanoparticles (AgNPs). The deposition of AgNPs on the surface of MNPs@CMCS could significantly increase its antimicrobial activity against planktonic cells due to the dual action of CMCS and AgNPs. Due to its high magnetism, the as-prepared MNPs@CMCS-Ag could be efficiently delivered into an existing biofilm under the guidance of an applied magnetic field. Without direct contact, the Ag ions and/or radical oxygen species (ROS) released from the deposited Ag nanoparticles could effectively kill the bacteria embedded in the extracellular polymeric substances (EPS) matrix of biofilm. Copyright © 2016 Elsevier B.V. All rights reserved.

An Ultra-Low Voltage Analog Front End for Strain Gauge Sensory System Application in 0.18µm CMOS

NASA Astrophysics Data System (ADS)

Edward, Alexander; Chan, Pak Kwong

This paper presents analysis and design of a new ultra-low voltage analog front end (AFE) dedicated to strain sensor applications. The AFE, designed in 0.18µm CMOS process, features a chopper-stabilized instrumentation amplifier (IA), a balanced active MOSFET-C 2nd order low pass filter (LPF), a clock generator and a voltage booster which operate at supply voltage (Vdd) of 0.6V. The designed IA achieves 30dB of closed-loop gain, 101dB of common-mode rejection ratio (CMRR) at 50Hz, 80dB of power-supply rejection ratio (PSRR) at 50Hz, thermal noise floor of 53.4 nV/√Hz, current consumption of 14µA, and noise efficiency factor (NEF) of 9.7. The high CMRR and rail-to-rail output swing capability is attributed to a new low voltage realization of the active-bootstrapped technique using a pseudo-differential gain-boosting operational transconductance amplifier (OTA) and proposed current-driven bulk (CDB) biasing technique. An output capacitor-less low-dropout regulator (LDO), with a new fast start-up LPF technique, is used to regulate this 0.6V supply from a 0.8-1.0V energy harvesting power source. It achieves power supply rejection (PSR) of 42dB at frequency of 1MHz. A cascode compensated pseudo differential amplifier is used as the filter's building block for low power design. The filter's single-ended-to-balanced converter is implemented using a new low voltage amplifier with two-stage common-mode cancellation. The overall AFE was simulated to have 65.6dB of signal-to-noise ratio (SNR), total harmonic distortion (THD) of less than 0.9% for a 100Hz sinusoidal maximum input signal, bandwidth of 2kHz, and power consumption of 51.2µW. Spectre RF simulations were performed to validate the design using BSIM3V3 transistor models provided by GLOBALFOUNDRIES 0.18µm CMOS process.

17 CFR 36.2 - Exempt boards of trade.

Code of Federal Regulations, 2011 CFR

2011-04-01

... Section 36.2 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION EXEMPT MARKETS § 36.2... deliverable supply; (ii) A deliverable supply that is sufficiently large, and a cash market sufficiently... manipulation; or (iii)No cash market. (2) The commodities that meet the criteria of paragraph (a)(1) of this...

17 CFR 36.2 - Exempt boards of trade.

Code of Federal Regulations, 2010 CFR

2010-04-01

... Section 36.2 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION EXEMPT MARKETS § 36.2... deliverable supply; (ii) A deliverable supply that is sufficiently large, and a cash market sufficiently... manipulation; or (iii)No cash market. (2) The commodities that meet the criteria of paragraph (a)(1) of this...

17 CFR 36.2 - Exempt boards of trade.

Code of Federal Regulations, 2012 CFR

2012-04-01

... Section 36.2 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION EXEMPT MARKETS § 36.2... deliverable supply; (ii) A deliverable supply that is sufficiently large, and a cash market sufficiently... manipulation; or (iii)No cash market. (2) The commodities that meet the criteria of paragraph (a)(1) of this...

Altarum restricted use technology study : interim report, deliverable 3.1 : list of invitees for the focus group

DOT National Transportation Integrated Search

2005-09-01

This study, an 18-month effort, seeks to apply restricted use technology to the mandates of MDOT. For Deliverable 3.1 described in the Work Plan governing the Altarum Restricted Use Technology Study, the Altarum project team is required to provide a ...

Report On Stakeholders Analysis Fast-Trac Phase Iii Deliverables, #5 One Set Of Stakeholder Readings, #6. Final Version Of The Stakeholders? Questionnaire, #7. Stakeholders? Analysis Report

DOT National Transportation Integrated Search

1996-12-10

THIS STUDY WAS UNDERTAKEN TO IDENTIFY AND EVALUATE CRITERIA BY WHICH THE PUBLIC, AND CERTAIN STAKEHOLDER GROUPS WITHIN THE PUBLIC, WILL JUDGE THE MERITS OF THE FAST-TRAC SYSTEM. OVER A PERIOD OF TWO YEARS, THREE SURVEYS WERE CONDUCTED TO OBTAIN SPECI...

Extensible Adaptive System for STEM Learning

DTIC Science & Technology

2013-07-16

Copyright 2013 Raytheon BBN Technologies Corp. All Rights Reserved ONR STEM Grand Challenge Extensible Adaptive System for STEM Learning ...Contract # N00014-12-C-0535 Raytheon BBN Technologies Corp. (BBN) Reference # 14217 In partial fulfillment of contract deliverable item # A001...Quarterly Progress Report #2 April 7, 2013 –July 6, 2013 Submitted July 16, 2013 BBN Technical POC: John Makhoul Raytheon BBN Technologies

Application of a TNF-alpha-inhibitor into the scala tympany after cochlear electrode insertion trauma in guinea pigs: preliminary audiologic results.

PubMed

Ihler, Friedrich; Pelz, Sabrina; Coors, Melanie; Matthias, Christoph; Canis, Martin

2014-11-01

Cochlear implantation trauma causes both macroscopic and inflammatory trauma. The aim of the present study was to evaluate the effectiveness of the TNF-alpha inhibitor etanercept applied after cochlear implantation trauma on the preservation of acoustic hearing. Guinea pigs were randomly assigned to three groups receiving cochlear implantation trauma by cochleostomy. In one group, the site was sealed by bone cement with no further treatment. A second group was additionally implanted with an osmotic minipump delivering artificial perilymph into the scala tympani for seven days. In the third group, etanercept 1 mg/ml was added to artificial perilymph. Hearing was assessed by auditory brainstem responses at 2, 4, 6, and 8 kHz prior to and after surgery and on days 3, 5, 7, 14, 28. Fifteen healthy guinea pigs. The trauma led to threshold shifts from 50.3 dB ± 16.3 dB to 68.0 dB ± 19.3 dB. Hearing thresholds were significantly lower in etanercept-treated animals compared to controls on day 28 at 8 kHz and from day 3 onwards at 4 and 2 kHz (p < 0.01; two-way RM ANOVA / Bonferroni t-test). The application of etanercept led to preservation of acoustic hearing after cochlear implantation trauma.

47 CFR 1.736 - Complaints filed pursuant to 47 U.S.C. 271(d)(6)(B).

Code of Federal Regulations, 2010 CFR

2010-10-01

... Complaints filed pursuant to 47 U.S.C. 271(d)(6)(B). (a) Where a complaint is filed pursuant to 47 U.S.C. 271... deadline contained in 47 U.S.C. 271(d)(6)(B) in the following manner: (1) The complainant shall so indicate... filed pursuant to 47 U.S.C. 271(d)(6)(B) will not be entertained by the Commission staff subsequent to...

47 CFR 1.736 - Complaints filed pursuant to 47 U.S.C. 271(d)(6)(B).

Code of Federal Regulations, 2014 CFR

2014-10-01

... Complaints filed pursuant to 47 U.S.C. 271(d)(6)(B). (a) Where a complaint is filed pursuant to 47 U.S.C. 271... deadline contained in 47 U.S.C. 271(d)(6)(B) in the following manner: (1) The complainant shall so indicate... filed pursuant to 47 U.S.C. 271(d)(6)(B) will not be entertained by the Commission staff subsequent to...

47 CFR 1.736 - Complaints filed pursuant to 47 U.S.C. 271(d)(6)(B).

Code of Federal Regulations, 2011 CFR

2011-10-01

... Complaints filed pursuant to 47 U.S.C. 271(d)(6)(B). (a) Where a complaint is filed pursuant to 47 U.S.C. 271... deadline contained in 47 U.S.C. 271(d)(6)(B) in the following manner: (1) The complainant shall so indicate... filed pursuant to 47 U.S.C. 271(d)(6)(B) will not be entertained by the Commission staff subsequent to...

47 CFR 1.736 - Complaints filed pursuant to 47 U.S.C. 271(d)(6)(B).

Code of Federal Regulations, 2012 CFR

2012-10-01

... Complaints filed pursuant to 47 U.S.C. 271(d)(6)(B). (a) Where a complaint is filed pursuant to 47 U.S.C. 271... deadline contained in 47 U.S.C. 271(d)(6)(B) in the following manner: (1) The complainant shall so indicate... filed pursuant to 47 U.S.C. 271(d)(6)(B) will not be entertained by the Commission staff subsequent to...

47 CFR 1.736 - Complaints filed pursuant to 47 U.S.C. 271(d)(6)(B).

Code of Federal Regulations, 2013 CFR

2013-10-01

... Complaints filed pursuant to 47 U.S.C. 271(d)(6)(B). (a) Where a complaint is filed pursuant to 47 U.S.C. 271... deadline contained in 47 U.S.C. 271(d)(6)(B) in the following manner: (1) The complainant shall so indicate... filed pursuant to 47 U.S.C. 271(d)(6)(B) will not be entertained by the Commission staff subsequent to...

Use of a 1-dB decrease in C/N\\0x2080AS the GPS interference protection criterion : global positioning systems directorate.

DOT National Transportation Integrated Search

2017-03-30

A 1 dB decrease in the carrier-to-noise (C/N) ratio is equivalent to a -6 dB interference-to-noise (I/N) ratio and a 1 dB increase in the noise floor ((I+N)/N). Regulations alternate between referencing the 1 dB decrease in C/N, -6 dB I/N ratio, and ...

The TMIS life-cycle process document, revision A

NASA Technical Reports Server (NTRS)

1991-01-01

The Technical and Management Information System (TMIS) Life-Cycle Process Document describes the processes that shall be followed in the definition, design, development, test, deployment, and operation of all TMIS products and data base applications. This document is a roll out of TMIS Standards Document (SSP 30546). The purpose of this document is to define the life cycle methodology that the developers of all products and data base applications and any subsequent modifications shall follow. Included in this methodology are descriptions of the tasks, deliverables, reviews, and approvals that are required before a product or data base application is accepted in the TMIS environment.

GENETIC MAPPING OF VOCALIZATION TO A SERIES OF INCREASING ACUTE FOOTSHOCKS USING B6.A CONSOMIC AND B6.D2 CONGENIC MOUSE STRAINS

DOE Office of Scientific and Technical Information (OSTI.GOV)

Matthews, Douglas B; Chesler, Elissa J; Cook, Melloni N.

2008-01-01

Footshock response is used to study biological functions in mammals. However, the genetics underlying variability in footshock sensitivity are not well understood. In the current studies, a panel of B6.A consomic mouse strains, two B6.D2 congenic mouse strains and the progenitor strains were screened for footshock sensitivity as measured by audible vocalization. It was found that A/J (A) mice and C57BL/6J (B6) mice with an A Chromosome 1 (Chr 1) were less sensitive to footshock compared to B6 animals. Furthermore, the offspring of Chr 1 consomic mice crossed with B6 mice had vocalization levels that were intermediate to A/J andmore » B6 animals. A F2 mapping panel revealed two significant QTLs for footshock vocalization centered around D1Mit490 and D1Mit206 on Chr 1. The role of these Chr 1 loci in footshock sensitivity was confirmed in B6.D2 congenic mice. These data identify genetic regions involved in footshock sensitivity and establish additional mouse resources for use in investigating complex behaviors.« less

Hybrid and concatenated coding applications.

NASA Technical Reports Server (NTRS)

Hofman, L. B.; Odenwalder, J. P.

1972-01-01

Results of a study to evaluate the performance and implementation complexity of a concatenated and a hybrid coding system for moderate-speed deep-space applications. It is shown that with a total complexity of less than three times that of the basic Viterbi decoder, concatenated coding improves a constraint length 8 rate 1/3 Viterbi decoding system by 1.1 and 2.6 dB at bit error probabilities of 0.0001 and one hundred millionth, respectively. With a somewhat greater total complexity, the hybrid coding system is shown to obtain a 0.9-dB computational performance improvement over the basic rate 1/3 sequential decoding system. Although substantial, these complexities are much less than those required to achieve the same performances with more complex Viterbi or sequential decoder systems.

Achieving Highly Efficient Nonfullerene Organic Solar Cells with Improved Intermolecular Interaction and Open-Circuit Voltage

DOE PAGES

Yao, Huifeng; Ye, Long; Hou, Junxian; ...

2017-03-29

Here, a new acceptor–donor–acceptor-structured nonfullerene acceptor ITCC (3,9-bis(4-(1,1-dicyanomethylene)-3-methylene-2-oxo-cyclopenta[b]thiophen)-5,5,11,11-tetrakis(4-hexylphenyl)-dithieno[2,3- d':2,3- d'] -s-indaceno[1,2- b:5,6- b']-dithiophene) is designed and synthesized via simple end-group modification. ITCC shows improved electron-transport properties and a high-lying lowest unoccupied molecular orbital level. A power conversion efficiency of 11.4% with an impressive V OC of over 1 V is recorded in photovoltaic devices, suggesting that ITCC has great potential for applications in tandem organic solar cells.

Application of Nanotechnology in the Targeted Release of Anticancer Drugs in Ovarian Cancer Treatment

DTIC Science & Technology

2007-12-01

diagnosis, and treatment of cancer . When loaded with chemotherapeutic agents, nanoparticle delivery to cancerous tissues relative to healthy tissues may be...Targeted Release of Anticancer Drugs in Ovarian Cancer Treatment PRINCIPAL INVESTIGATOR: Colleen Feltmate, M.D...Anticancer Drugs in Ovarian Cancer Treatment 5b. GRANT NUMBER W81XWH-06-1-0177 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT NUMBER Colleen

Successful mouse cloning of an outbred strain by trichostatin A treatment after somatic nuclear transfer.

PubMed

Kishigami, Satoshi; Bui, Hong-Thuy; Wakayama, Sayaka; Tokunaga, Kenzo; Van Thuan, Nguyen; Hikichi, Takafusa; Mizutani, Eiji; Ohta, Hiroshi; Suetsugu, Rinako; Sata, Tetsutaro; Wakayama, Teruhiko

2007-02-01

Although the somatic cloning technique has been used for numerous applications and basic research of reprogramming in various species, extremely low success rates have plagued this technique for a decade. Further in mice, the "clonable" strains have been limited to mainly hybrid F1 strains such as B6D2F1. Recently, we established a new efficient cloning technique using trichostatin A (TSA) which leads to a 2-5 fold increase in success rates for mouse cloning of B6D2F1 cumulus cells. To further test the validity of this TSA cloning technique, we tried to clone the adult ICR mouse, an outbred strain, which has never been directly cloned before. Only when TSA was used did we obtain both male and female cloned mice from cumulus and fibroblast cells of adult ICR mice with 4-5% success rates, which is comparable to 5-7% of B6D2F1. Thus, the TSA treatment is the first cloning technique to allow us to successfully clone outbred mice, demonstrating that this technique not only improves the success rates of cloning from hybrid strains, but also enables mouse cloning from normally "unclonable" strains.

DFT computational analysis of piracetam.

PubMed

Rajesh, P; Gunasekaran, S; Seshadri, S; Gnanasambandan, T

2014-11-11

Density functional theory calculation with B3LYP using 6-31G(d,p) and 6-31++G(d,p) basis set have been used to determine ground state molecular geometries. The first order hyperpolarizability (β0) and related properties (β, α0 and Δα) of piracetam is calculated using B3LYP/6-31G(d,p) method on the finite-field approach. The stability of molecule has been analyzed by using NBO/NLMO analysis. The calculation of first hyperpolarizability shows that the molecule is an attractive molecule for future applications in non-linear optics. Molecular electrostatic potential (MEP) at a point in the space around a molecule gives an indication of the net electrostatic effect produced at that point by the total charge distribution of the molecule. The calculated HOMO and LUMO energies show that charge transfer occurs within these molecules. Mulliken population analysis on atomic charge is also calculated. Because of vibrational analysis, the thermodynamic properties of the title compound at different temperatures have been calculated. Finally, the UV-Vis spectra and electronic absorption properties are explained and illustrated from the frontier molecular orbitals. Copyright © 2014 Elsevier B.V. All rights reserved.

The use of D-optimal mixture design in optimising okara soap formulation for stratum corneum application.

PubMed

Borhan, Farrah Payyadhah; Abd Gani, Siti Salwa; Shamsuddin, Rosnah

2014-01-01

Okara, soybean waste from tofu and soymilk production, was utilised as a natural antioxidant in soap formulation for stratum corneum application. D-optimal mixture design was employed to investigate the influence of the main compositions of okara soap containing different fatty acid and oils (virgin coconut oil A (24-28% w/w), olive oil B (15-20% w/w), palm oil C (6-10% w/w), castor oil D (15-20% w/w), cocoa butter E (6-10% w/w), and okara F (2-7% w/w)) by saponification process on the response hardness of the soap. The experimental data were utilized to carry out analysis of variance (ANOVA) and to develop a polynomial regression model for okara soap hardness in terms of the six design factors considered in this study. Results revealed that the best mixture was the formulation that included 26.537% A, 19.999% B, 9.998% C, 16.241% D, 7.633% E, and 7.000% F. The results proved that the difference in the level of fatty acid and oils in the formulation significantly affects the hardness of soap. Depending on the desirable level of those six variables, creation of okara based soap with desirable properties better than those of commercial ones is possible.

32 CFR Appendix B to Part 295 - Exemptions

Code of Federal Regulations, 2014 CFR

2014-07-01

... with an application for a research grant, or with a report while research is in progress. (6) Technical... their products. (d) Information of a speculative, tentative, or evaluative nature of such matters as... interests or would impede legitimate Government functions. (e) Trade secret or other confidential research...

32 CFR Appendix B to Part 295 - Exemptions

Code of Federal Regulations, 2010 CFR

2010-07-01

... with an application for a research grant, or with a report while research is in progress. (6) Technical... their products. (d) Information of a speculative, tentative, or evaluative nature of such matters as... interests or would impede legitimate Government functions. (e) Trade secret or other confidential research...

32 CFR Appendix B to Part 295 - Exemptions

Code of Federal Regulations, 2013 CFR

2013-07-01

... with an application for a research grant, or with a report while research is in progress. (6) Technical... their products. (d) Information of a speculative, tentative, or evaluative nature of such matters as... interests or would impede legitimate Government functions. (e) Trade secret or other confidential research...

32 CFR Appendix B to Part 295 - Exemptions

Code of Federal Regulations, 2012 CFR

2012-07-01

... with an application for a research grant, or with a report while research is in progress. (6) Technical... their products. (d) Information of a speculative, tentative, or evaluative nature of such matters as... interests or would impede legitimate Government functions. (e) Trade secret or other confidential research...

32 CFR Appendix B to Part 295 - Exemptions

Code of Federal Regulations, 2011 CFR

2011-07-01

... with an application for a research grant, or with a report while research is in progress. (6) Technical... their products. (d) Information of a speculative, tentative, or evaluative nature of such matters as... interests or would impede legitimate Government functions. (e) Trade secret or other confidential research...

SU-F-BRB-12: A Novel Haar Wavelet Based Approach to Deliver Non-Coplanar Intensity Modulated Radiotherapy Using Sparse Orthogonal Collimators

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nguyen, D; Ruan, D; Low, D

2015-06-15

Purpose: Existing efforts to replace complex multileaf collimator (MLC) by simple jaws for intensity modulated radiation therapy (IMRT) resulted in unacceptable compromise in plan quality and delivery efficiency. We introduce a novel fluence map segmentation method based on compressed sensing for plan delivery using a simplified sparse orthogonal collimator (SOC) on the 4π non-coplanar radiotherapy platform. Methods: 4π plans with varying prescription doses were first created by automatically selecting and optimizing 20 non-coplanar beams for 2 GBM, 2 head & neck, and 2 lung patients. To create deliverable 4π plans using SOC, which are two pairs of orthogonal collimators withmore » 1 to 4 leaves in each collimator bank, a Haar Fluence Optimization (HFO) method was used to regulate the number of Haar wavelet coefficients while maximizing the dose fidelity to the ideal prescription. The plans were directly stratified utilizing the optimized Haar wavelet rectangular basis. A matching number of deliverable segments were stratified for the MLC-based plans. Results: Compared to the MLC-based 4π plans, the SOC-based 4π plans increased the average PTV dose homogeneity from 0.811 to 0.913. PTV D98 and D99 were improved by 3.53% and 5.60% of the corresponding prescription doses. The average mean and maximal OAR doses slightly increased by 0.57% and 2.57% of the prescription doses. The average number of segments ranged between 5 and 30 per beam. The collimator travel time to create the segments decreased with increasing leaf numbers in the SOC. The two and four leaf designs were 1.71 and 1.93 times more efficient, on average, than the single leaf design. Conclusion: The innovative dose domain optimization based on compressed sensing enables uncompromised 4π non-coplanar IMRT dose delivery using simple rectangular segments that are deliverable using a sparse orthogonal collimator, which only requires 8 to 16 leaves yet is unlimited in modulation resolution. This work is supported in part by Varian Medical Systems, Inc. and NIH R43 CA18339.« less

Fiber Optic Microsensor for Receptor-Based Assays

DTIC Science & Technology

1988-09-01

MONITORING ORGANIZATION ORDInc.(if applicable ) 6c. ADDRESS (CWty Sta~te, and ZIP code) 7b. ADDRESS (City, State, an~d ZIP=Cd) Nahant, MA 019081 Sa, NAME OF...yield B-PE B-phycoerythrin 545 575 2,410,000 0.98 R-PE R-phycoerythrin 565 578 11960,000 0.68 CPC C- phycocyanine 620 650 1,690,000 0.51 A-PC...efficient transfer occurred for unit magnification. Figure 3 shows the optical design. Evaluation of the instrument was done with both A- phycocyanine

Feasibility Study for Low Drag Acoustic Liners Final Report

NASA Technical Reports Server (NTRS)

Riedel, Brian; Wu, Jackie

2017-01-01

This report documents the design and structural analysis as a final deliverable for the Phase 1 contract activity. Also included is a community noise test plan, which is a key deliverable for Phase 2. Finally, a high-level estimate (Phase 3 deliverable) is provided for the work statement of Phases 2-4, which covers the build of two inlet test articles, planning and execution of a flight test with the test inlets, as well as data analysis and final documentation. The two test inlets will be compared to the production baseline inlet configuration. There is also a plan to test one of the inlets "hardwalled" using speed tape or some other similar tape to block the acoustic perforations.

Higher-Order Mixed Finite Element Methods for Time Domain Electromagnetics

DOE Office of Scientific and Technical Information (OSTI.GOV)

White, D; Stowell, M; Koning, J

This is the final report for LDRD 01-ERD-005. The Principal Investigator was Niel Madsen of the Defense Sciences Engineering Division (DSED). Collaborators included Daniel White, Joe Koning and Nathan Champagne of DSED, Mark Stowell of Center for Applications Development and Software Engineering (CADSE), and Ph.D. students Rob Rieben and Aaron Fisher at the UC Davis Department of Applied Science. It should be noted that the students were partially supported by the LLNL Student-Employee Graduate Research Fellow program. We begin with an Introduction which provides background and motivation for this research effort. Section II contains high-level description of our Approach, andmore » Section III summarizes our key research Accomplishments. A description of the Software deliverables is provided in Section IV, and Section V includes simulation Validation and Results. It should be noted we do not get into the mathematical details in this report, rather these can be found in our publications which are listed in Section III.« less

47 CFR 73.4280 - Character evaluation of broadcast applicants.

Code of Federal Regulations, 2010 CFR

2010-10-01

... Docket 78-108, FCC 85-648, adopted December 10, 1985. 102 FCC 2d 1179; 51 FR 3049, January 23, 1986. (b) See Policy Statement and Order, FCC 90-195, adopted May 10, 1990. 5 FCC Rcd 3252, 55 FR 23082, June 6, 1990. (c) See Memorandum Opinion and Order, FCC 91-146, adopted May 1, 1991. 6 FCC Rcd 3448, 56 FR...

Chamber B Thermal/Vacuum Chamber: User Test Planning Guide

NASA Technical Reports Server (NTRS)

Montz, Mike E.

2012-01-01

Test process, milestones and inputs are unknowns to first-time users of Chamber B. The User Test Planning Guide aids in establishing expectations for both NASA and non-NASA facility customers. The potential audience for this guide includes both internal and commercial spaceflight hardware/software developers. It is intended to assist their test engineering personnel in test planning and execution. Material covered includes a roadmap of the test process, roles and responsibilities of facility and user, major milestones, facility capabilities, and inputs required by the facility. Samples of deliverables, test article interfaces, and inputs necessary to define test scope, cost, and schedule are included as an appendix to the guide.

Differential Equations, Related Problems of Pade Approximations and Computer Applications

DTIC Science & Technology

1988-12-31

Building 410 1z C ’. O, 4- ~ ~ t ~ Boiling, APE DC 20332-6448 k &L jY naIc l iV n~a -(2)7 _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ 8a. NAME OF FUNDING / SPONSORING 1b...SECUAITY C SSIFICATION 0 UNCLASSIFIEO/UNLIMITE-D 0 SAME AS RPT. C3 DTIC USERS ((1 ’ ’ 𔃺C 222. NAME OP RESPONSILI INDIVIDUAL 22b. TELEPHONE (include A...0Ŗ- IN A C h M 6 w V21 767- i-= DForm 1473. Je N 6Previou editons are ouch"e PAC 89 5 1 22 5 Grant No. AFOSR-87-0117 - 9 )6 2 Differential

Protective effects of murine monoclonal antibodies in experimental septicemia: E. coli antibodies protect against different serotypes of E. coli.

PubMed

Salles, M F; Mandine, E; Zalisz, R; Guenounou, M; Smets, P

1989-04-01

Murine monoclonal antibodies that bind outer membrane antigens of the J5 mutant of Escherichia coli O111:B4 were derived from spleen cells of BALB/c mice immunized with killed whole cells and boosted with lipopolysaccharide (LPS) and LPS-associated proteins. Seven hybridomas were selected for their reactivity against the J5 LPS; they cross-reacted with O111, O55, O127, and O128 E. coli LPS. One (B7B3) also reacted with the Serratia marcescens LPS and Klebsiella pneumoniae lipid A. A protective effect was obtained with D6B4 antibody in a lethal endotoxemia model induced by LPS from O111, O127, and O128 E. coli serotypes in D-galactosamine-sensitized mice. D6B4 and D6B3 antibodies protected mice infected with E. coli O111:B4, when administered before infection. The D6B4 antibody was also protective when administered after infection. The antibodies D6B3 and D4B5 were protective in heterologous infection induced by E. coli O2:K1.

SU-F-T-344: Commissioning Constant Dose Rate VMAT in the Raystation Treatment Planning System for a Varian Clinac IX

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pursley, J; Gueorguiev, G; Prichard, H

Purpose: To demonstrate the commissioning of constant dose rate volumetric modulated arc therapy (VMAT) in the Raystation treatment planning system for a Varian Clinac iX with Exact couch. Methods: Constant dose rate (CDR) VMAT is an option in the Raystation treatment planning system, enabling VMAT delivery on Varian linacs without a RapidArc upgrade. Raystation 4.7 was used to commission CDR-VMAT for a Varian Clinac iX. Raystation arc model parameters were selected to match machine deliverability characteristics. A Varian Exact couch model was added to Raystation 4.7 and commissioned for use in VMAT optimization. CDR-VMAT commissioning checks were performed on themore » linac, including patient-specific QA measurements for 10 test patients using both the ArcCHECK from Sun Nuclear Corporation and COMPASS from IBA Dosimetry. Multi-criteria optimization (MCO) in Raystation was used for CDR-VMAT planning. Results: Raystation 4.7 generated clinically acceptable and deliverable CDR-VMAT plans for the Varian Clinac. VMAT plans were optimized including a model of the Exact couch with both rails in the out positions. CDR-VMAT plans generated with MCO in Raystation were dosimetrically comparable to Raystation MCO-generated IMRT plans. Patient-specific QA measurements with the ArcCHECK on the couch showed good agreement with the treatment planning system prediction. Patient-specific, structure-specific, multi-statistical parameter 3D QA measurements with gantry-mounted COMPASS also showed good agreement. Conclusion: Constant dose rate VMAT was successfully modeled in Raystation 4.7 for a Varian Clinac iX, and Raystation’s multicriteria optimization generated constant dose rate VMAT plans which were deliverable and dosimetrically comparable to IMRT plans.« less

A Structure Design Method for Reduction of MRI Acoustic Noise.

PubMed

Nan, Jiaofen; Zong, Nannan; Chen, Qiqiang; Zhang, Liangliang; Zheng, Qian; Xia, Yongquan

2017-01-01

The acoustic problem of the split gradient coil is one challenge in a Magnetic Resonance Imaging and Linear Accelerator (MRI-LINAC) system. In this paper, we aimed to develop a scheme to reduce the acoustic noise of the split gradient coil. First, a split gradient assembly with an asymmetric configuration was designed to avoid vibration in same resonant modes for the two assembly cylinders. Next, the outer ends of the split main magnet were constructed using horn structures, which can distribute the acoustic field away from patient region. Finally, a finite element method (FEM) was used to quantitatively evaluate the effectiveness of the above acoustic noise reduction scheme. Simulation results found that the noise could be maximally reduced by 6.9 dB and 5.6 dB inside and outside the central gap of the split MRI system, respectively, by increasing the length of one gradient assembly cylinder by 20 cm. The optimized horn length was observed to be 55 cm, which could reduce noise by up to 7.4 dB and 5.4 dB inside and outside the central gap, respectively. The proposed design could effectively reduce the acoustic noise without any influence on the application of other noise reduction methods.

78 FR 35338 - Self-Regulatory Organizations; BOX Options Exchange LLC; Notice of Filing and Immediate...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-06-12

... trading option contracts overlying 1,000 SPDR[supreg] S&P 500[supreg] exchange-traded fund shares (``SPY''),\\3\\ or (``Jumbo SPY Options'').\\4\\ Whereas standard options contracts represent a deliverable of 100... the number of deliverable shares, Jumbo SPY Options have the same terms and contract characteristics...

A Quantitative Study into the Information Technology Project Portfolio Practice: The Impact on Information Technology Project Deliverables

ERIC Educational Resources Information Center

Yu, Wei

2013-01-01

This dissertation applied the quantitative approach to the data gathered from online survey questionnaires regarding the three objects: Information Technology (IT) Portfolio Management, IT-Business Alignment, and IT Project Deliverables. By studying this data, this dissertation uncovered the underlying relationships that exist between the…

Measurement of the branching fractions and CP asymmetry of B--->D(0)((CP))K- decays with the BABAR detector.

PubMed

Aubert, B; Barate, R; Boutigny, D; Gaillard, J-M; Hicheur, A; Karyotakis, Y; Lees, J P; Robbe, P; Tisserand, V; Zghiche, A; Palano, A; Pompili, A; Chen, J C; Qi, N D; Rong, G; Wang, P; Zhu, Y S; Eigen, G; Ofte, I; Stugu, B; Abrams, G S; Borgland, A W; Breon, A B; Brown, D N; Button-Shafer, J; Cahn, R N; Charles, E; Day, C T; Gill, M S; Gritsan, A V; Groysman, Y; Jacobsen, R G; Kadel, R W; Kadyk, J; Kerth, L T; Kolomensky, Yu G; Kukartsev, G; LeClerc, C; Levi, M E; Lynch, G; Mir, L M; Oddone, P J; Orimoto, T J; Pripstein, M; Roe, N A; Romosan, A; Ronan, M T; Shelkov, V G; Telnov, A V; Wenzel, W A; Ford, K; Harrison, T J; Hawkes, C M; Knowles, D J; Morgan, S E; Penny, R C; Watson, A T; Watson, N K; Goetzen, K; Koch, H; Lewandowski, B; Pelizaeus, M; Peters, K; Schmuecker, H; Steinke, M; Boyd, J T; Chevalier, N; Cottingham, W N; Kelly, M P; Latham, T E; Mackay, C; Wilson, F F; Abe, K; Cuhadar-Donszelmann, T; Hearty, C; Mattison, T S; McKenna, J A; Thiessen, D; Kyberd, P; McKemey, A K; Teodorescu, L; Blinov, V E; Bukin, A D; Golubev, V B; Ivanchenko, V N; Kravchenko, E A; Onuchin, A P; Serednyakov, S I; Skovpen, Yu I; Solodov, E P; Yushkov, A N; Best, D; Bruinsma, M; Chao, M; Eschrich, I; Kirkby, D; Lankford, A J; Mandelkern, M; Mommsen, R K; Roethel, W; Stoker, D P; Buchanan, C; Hartfiel, B L; Gary, J W; Shen, B C; Wang, K; Del Re, D; Hadavand, H K; Hill, E J; MacFarlane, D B; Paar, H P; Rahatlou, Sh; Sharma, V; Berryhill, J W; Campagnari, C; Dahmes, B; Kuznetsova, N; Levy, S L; Long, O; Lu, A; Mazur, M A; Richman, J D; Verkerke, W; Beck, T W; Beringer, J; Eisner, A M; Heusch, C A; Lockman, W S; Schalk, T; Schmitz, R E; Schumm, B A; Seiden, A; Turri, M; Walkowiak, W; Williams, D C; Wilson, M G; Albert, J; Chen, E; Dubois-Felsmann, G P; Dvoretskii, A; Hitlin, D G; Narsky, I; Piatenko, T; Porter, F C; Ryd, A; Samuel, A; Yang, S; Jayatilleke, S; Mancinelli, G; Meadows, B T; Sokoloff, M D; Abe, T; Blanc, F; Bloom, P; Chen, S; Clark, P J; Ford, W T; Nauenberg, U; Olivas, A; Rankin, P; Roy, J; Smith, J G; Van Hoek, W C; Zhang, L; Harton, J L; Hu, T; Soffer, A; Toki, W H; Wilson, R J; Zhang, J; Aleksan, R; Emery, S; Gaidot, A; Ganzhur, S F; Giraud, P-F; Hamel De Monchenault, G; Kozanecki, W; Langer, M; Legendre, M; London, G W; Mayer, B; Schott, G; Vasseur, G; Yeche, Ch; Zito, M; Altenburg, D; Brandt, T; Brose, J; Colberg, T; Dickopp, M; Hauke, A; Lacker, H M; Maly, E; Müller-Pfefferkorn, R; Nogowski, R; Otto, S; Schubert, J; Schubert, K R; Schwierz, R; Spaan, B; Bernard, D; Bonneaud, G R; Brochard, F; Cohen-Tanugi, J; Grenier, P; Thiebaux, Ch; Vasileiadis, G; Verderi, M; Khan, A; Lavin, D; Muheim, F; Playfer, S; Swain, J E; Andreotti, M; Azzolini, V; Bettoni, D; Bozzi, C; Calabrese, R; Cibinetto, G; Luppi, E; Negrini, M; Piemontese, L; Sarti, A; Treadwell, E; Anulli, F; Baldini-Ferroli, R; Calcaterra, A; De Sangro, R; Falciai, D; Finocchiaro, G; Patteri, P; Peruzzi, I M; Piccolo, M; Zallo, A; Buzzo, A; Capra, R; Contri, R; Crosetti, G; Lo Vetere, M; Macri, M; Monge, M R; Passaggio, S; Patrignani, C; Robutti, E; Santroni, A; Tosi, S; Bailey, S; Morii, M; Won, E; Dubitzky, R S; Langenegger, U; Bhimji, W; Bowerman, D A; Dauncey, P D; Egede, U; Gaillard, J R; Morton, G W; Nash, J A; Sanders, P; Taylor, G P; Grenier, G J; Lee, S-J; Mallik, U; Cochran, J; Crawley, H B; Lamsa, J; Meyer, W T; Prell, S; Rosenberg, E I; Yi, J; Biasini, M; Pioppi, M; Davier, M; Grosdidier, G; Höcker, A; Laplace, S; Le Diberder, F; Lepeltier, V; Lutz, A M; Petersen, T C; Plaszczynski, S; Schune, M H; Tantot, L; Wormser, G; Brigljević, V; Cheng, C H; Lange, D J; Wright, D M; Bevan, A J; Fry, J R; Gabathuler, E; Gamet, R; Kay, M; Payne, D J; Sloane, R J; Touramanis, C; Back, J J; Cormack, C M; Harrison, P F; Shorthouse, H W; Vidal, P B; Brown, C L; Cowan, G; Flack, R L; Flaecher, H U; George, S; Green, M G; Kurup, A; Marker, C E; McMahon, T R; Ricciardi, S; Salvatore, F; Vaitsas, G; Winter, M A; Brown, D; Davis, C L; Allison, J; Barlow, N R; Barlow, R J; Hart, P A; Hodgkinson, M C; Jackson, F; Lafferty, G D; Lyon, A J; Weatherall, J H; Williams, J C; Farbin, A; Jawahery, A; Kovalskyi, D; Lae, C K; Lillard, V; Roberts, D A; Blaylock, G; Dallapiccola, C; Flood, K T; Hertzbach, S S; Kofler, R; Koptchev, V B; Moore, T B; Saremi, S; Staengle, H; Willocq, S; Cowan, R; Sciolla, G; Taylor, F; Yamamoto, R K; Mangeol, D J J; Patel, P M; Robertson, S H; Lazzaro, A; Palombo, F; Bauer, J M; Cremaldi, L; Eschenburg, V; Godang, R; Kroeger, R; Reidy, J; Sanders, D A; Summers, D J; Zhao, H W; Brunet, S; Cote-Ahern, D; Taras, P; Nicholson, H; Raven, G; Wilden, L; Cartaro, C; Cavallo, N; De Nardo, G; Fabozzi, F; Gatto, C; Lista, L; Paolucci, P; Piccolo, D; Sciacca, C; Jessop, C P; LoSecco, J M; Gabriel, T A; Brau, B; Gan, K K; Honscheid, K; Hufnagel, D; Kagan, H; Kass, R; Pulliam, T; Wong, Q K; Brau, J; Frey, R; Potter, C T; Sinev, N B; Strom, D; Torrence, E; Colecchia, F; Dorigo, A; Galeazzi, F; Margoni, M; Morandin, M; Posocco, M; Rotondo, M; Simonetto, F; Stroili, R; Tiozzo, G; Voci, C; Benayoun, M; Briand, H; Chauveau, J; David, P; De la Vaissière, Ch; Del Buono, L; Hamon, O; John, M J J; Leruste, Ph; Ocariz, J; Pivk, M; Roos, L; Stark, J; T'Jampens, S; Therin, G; Manfredi, P F; Re, V; Behera, P K; Gladney, L; Guo, Q H; Panetta, J; Angelini, C; Batignani, G; Bettarini, S; Bondioli, M; Bucci, F; Calderini, G; Carpinelli, M; Del Gamba, V; Forti, F; Giorgi, M A; Lusiani, A; Marchiori, G; Martinez-Vidal, F; Morganti, M; Neri, N; Paoloni, E; Rama, M; Rizzo, G; Sandrelli, F; Walsh, J; Haire, M; Judd, D; Paick, K; Wagoner, D E; Cavoto, G; Danielson, N; Elmer, P; Lu, C; Miftakov, V; Olsen, J; Smith, A J S; Tanaka, H A; Bellini, F; Faccini, R; Ferrarotto, F; Ferroni, F; Gaspero, M; Mazzoni, M A; Morganti, S; Pierini, M; Piredda, G; Safai Tehrani, F; Voena, C; Christ, S; Wagner, G; Waldi, R; Adye, T; De Groot, N; Franek, B; Geddes, N I; Gopal, G P; Olaiya, E O; Xella, S M; Purohit, M V; Weidemann, A W; Yumiceva, F X; Aston, D; Bartoldus, R; Berger, N; Boyarski, A M; Buchmueller, O L; Convery, M R; Coupal, D P; Dong, D; Dorfan, J; Dujmic, D; Dunwoodie, W; Field, R C; Glanzman, T; Gowdy, S J; Grauges-Pous, E; Hadig, T; Halyo, V; Hryn'ova, T; Innes, W R; Kelsey, M H; Kim, P; Kocian, M L; Leith, D W G S; Libby, J; Luitz, S; Luth, V; Lynch, H L; Marsiske, H; Messner, R; Muller, D R; O'Grady, C P; Ozcan, V E; Perazzo, A; Perl, M; Petrak, S; Ratcliff, B N; Roodman, A; Salnikov, A A; Schindler, R H; Schwiening, J; Simi, G; Snyder, A; Soha, A; Stelzer, J; Su, D; Sullivan, M K; Va'vra, J; Wagner, S R; Weaver, M; Weinstein, A J R; Wisniewski, W J; Wright, D H; Young, C C; Burchat, P R; Edwards, A J; Meyer, T I; Petersen, B A; Roat, C; Ahmed, M; Ahmed, S; Alam, M S; Ernst, J A; Saeed, M A; Saleem, M; Wappler, F R; Bugg, W; Krishnamurthy, M; Spanier, S M; Eckmann, R; Kim, H; Ritchie, J L; Schwitters, R F; Izen, J M; Kitayama, I; Lou, X C; Ye, S; Bianchi, F; Bona, M; Gallo, F; Gamba, D; Borean, C; Bosisio, L; Della Ricca, G; Dittongo, S; Grancagnolo, S; Lanceri, L; Poropat, P; Vitale, L; Vuagnin, G; Panvini, R S; Banerjee, Sw; Brown, C M; Fortin, D; Jackson, P D; Kowalewski, R; Roney, J M; Band, H R; Dasu, S; Datta, M; Eichenbaum, A M; Johnson, J R; Kutter, P E; Li, H; Liu, R; Di Lodovico, F; Mihalyi, A; Mohapatra, A K; Pan, Y; Prepost, R; Sekula, S J; von Wimmersperg-Toeller, J H; Wu, J; Wu, S L; Yu, Z; Neal, H

2004-05-21

We present a study of B--->D(0)(CP)K- decays, where D(0)(CP) is reconstructed in CP-even channels, based on a sample of 88.8 x 10(6) Upsilon(4S)-->BB decays collected with the BABAR detector at the PEP-II e(+)e(-) storage ring. We measure the ratio of Cabibbo-suppressed to Cabibbo-favored branching fractions B(B--->D(0)(CP)K-)/B(B--->D(0)(CP)pi(-))=[8.8+/-1.6(stat)+/-0.5(syst)]x10(-2) and the CP asymmetry A(CP)=0.07+/-0.17(stat)+/-0.06(syst). We also measure B(B--->D0K-)/B(B--->D0pi(-))=[8.31+/-0.35(stat)+/-0.20(syst)]x10(-2) using a sample of 61.0 x 10(6) BB pairs.

Early Identification of SE-Related Program Risks: Opportunities for DoD Systems Engineering (SE) Transformation via SE Effectiveness Measures (EMs) and Evidence-Based Reviews

DTIC Science & Technology

2009-09-30

development of feasibility evidence for a 100-KSLOC project . It is good to note that the “sweet spots” are...incomplete without the FED, it becomes a first-class project deliverable. This implies that it needs a plan for its development , and that each task in...effective in supporting an aerospace flight hardware program at NASA; however, differences in the models used for project development and

Innovative Techniques for the Production of Low Cost 2D Laser Diode Arrays. Supplies or Services and Prices/Costs

DTIC Science & Technology

1991-12-31

continue on facet coatings, PL correlation to device performance, and CVD diamond. All global issues mentioned in Section 2.0 will be addresses and...The CVD diamond submounts will be hermetically sealed, electrically isolated and liquid cooled. (Deliverables: 5 5-bar arrays.) The following global ... issues not mentioned above will be investigated continuously throughout all four phases of this program: (1) design and development of a mask set to

Analytical Assessment of the Reciprocating Feed System

NASA Technical Reports Server (NTRS)

Eddleman, David E.; Blackmon, James B.; Morton, Christopher D.

2006-01-01

A preliminary analysis tool has been created in Microsoft Excel to determine deliverable payload mass, total system mass, and performance of spacecraft systems using various types of propellant feed systems. These mass estimates are conducted by inserting into the user interface the basic mission parameters (e.g., thrust, burn time, specific impulse, mixture ratio, etc.), system architecture (e.g., propulsion system type and characteristics, propellants, pressurization system type, etc.), and design properties (e.g., material properties, safety factors, etc.). Different propellant feed and pressurization systems are available for comparison in the program. This gives the user the ability to compare conventional pressure fed, reciprocating feed system (RFS), autogenous pressurization thrust augmentation (APTA RFS), and turbopump systems with the deliverable payload, inert mass, and total system mass being the primary comparison metrics. Analyses of several types of missions and spacecraft were conducted and it was found that the RFS offers a performance improvement, especially in terms of delivered payload, over conventional pressure fed systems. Furthermore, it is competitive with a turbopump system at low to moderate chamber pressures, up to approximately 1,500 psi. Various example cases estimating the system mass and deliverable payload of several types of spacecraft are presented that illustrate the potential system performance advantages of the RFS. In addition, a reliability assessment of the RFS was conducted, comparing it to simplified conventional pressure fed and turbopump systems, based on MIL-STD 756B; these results showed that the RFS offers higher reliability, and thus substantially longer periods between system refurbishment, than turbopump systems, and is competitive with conventional pressure fed systems. This is primarily the result of the intrinsic RFS fail-operational capability with three run tanks, since the system can operate with just two run tanks.

Brain stem auditory-evoked response of the nonanesthetized dog.

PubMed

Marshall, A E

1985-04-01

The brain stem auditory evoked-response was measured from a group of 24 healthy dogs under conditions suitable for clinical diagnostic use. The waveforms were identified, and analysis of amplitude ratios, latencies, and interpeak latencies were done. The group was subdivided into subgroups based on tranquilization, nontranquilization, sex, and weight. Differences were not observed among any of these subgroups. All dogs responded to the click stimulus from 30 dB to 90 dB, but only 62.5% of the dogs responded at 5 dB. The total number of peaks averaged 1.6 at 5 dB, increased linearly to 6.5 at 50 dB, and remained at 6.5 to 90 dB. Frequency of recognizability of each wave was tabulated for each stimulus intensity tested; recognizability increased with increased stimulus intensity. Amplitudes of waves increased with increasing stimulus intensity, but were highly variable. The 4th wave had the greatest amplitude at the lower stimulus intensities, and the 1st wave had the greatest amplitude at the higher stimulus intensities. Amplitude ratio of the 1st to 5th wave was greater than 1 at less than or equal to 50 dB stimulus intensity, and was 1 for stimulus intensities greater than 50 dB. Interpeak latencies did not change relative to stimulus intensities. Peak latencies of each wave averaged at 5-dB hearing level for the 1st to 6th waves were 2.03, 2.72, 3.23, 4.14, 4.41, and 6.05 ms, respectively; latencies of these 6 waves at 90 dB were 0.92, 1.79, 2.46, 3.03, 3.47, and 4.86 ms, respectively. Latency decreased between 0.009 to 0.014 ms/dB for the waves.

A Preliminary Study of Krypton Laser-Induced Fluorescence

DTIC Science & Technology

2010-07-01

Induced Fluorescence 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) William A. Hargus, Jr. (AFRL/RZSS) 5d. PROJECT NUMBER R 5e. TASK...replacement for xenon. This study examines the potential applications of laser-induced fluorescence as a plasma diagnostic technique for Kr I and Kr...II. Candidate electronic transitions are examined to determine their suitability for successful routine application of laser-induced fluorescence

Measurement of B(D+-->K(*0)l(+)nu(l)).

PubMed

Brandenburg, G; Ershov, A; Kim, D Y-J; Wilson, R; Benslama, K; Eisenstein, B I; Ernst, J; Gollin, G D; Hans, R M; Karliner, I; Lowrey, N; Marsh, M A; Plager, C; Sedlack, C; Selen, M; Thaler, J J; Williams, J; Edwards, K W; Ammar, R; Besson, D; Zhao, X; Anderson, S; Frolov, V V; Kubota, Y; Lee, S J; Li, S Z; Poling, R; Smith, A; Stepaniak, C J; Urheim, J; Ahmed, S; Alam, M S; Jian, L; Saleem, M; Wappler, F; Eckhart, E; Gan, K K; Gwon, C; Hart, T; Honscheid, K; Hufnagel, D; Kagan, H; Kass, R; Pedlar, T K; Thayer, J B; Von Toerne, E; Wilksen, T; Zoeller, M M; Richichi, S J; Severini, H; Skubic, P; Dytman, S A; Nam, S; Savinov, V; Chen, S; Hinson, J W; Lee, J; Miller, D H; Pavlunin, V; Shibata, E I; Shipsey, I P J; Cronin-Hennessy, D; Lyon, A L; Park, C S; Park, W; Thorndike, E H; Coan, T E; Gao, Y S; Liu, F; Maravin, Y; Narsky, I; Stroynowski, R; Ye, J; Artuso, M; Boulahouache, C; Bukin, K; Dambasuren, E; Mountain, R; Skwarnicki, T; Stone, S; Wang, J C; Mahmood, A H; Csorna, S E; Danko, I; Xu, Z; Bonvicini, G; Cinabro, D; Dubrovin, M; McGee, S; Bornheim, A; Lipeles, E; Pappas, S P; Shapiro, A; Sun, W M; Weinstein, A J; Masek, G; Paar, H P; Mahapatra, R; Briere, R A; Chen, G P; Ferguson, T; Tatishvili, G; Vogel, H; Adam, N E; Alexander, J P; Bebek, C; Berkelman, K; Blanc, F; Boisvert, V; Cassel, D G; Drell, P S; Duboscq, J E; Ecklund, K M; Ehrlich, R; Gibbons, L; Gittelman, B; Gray, S W; Hartill, D L; Heltsley, B K; Hsu, L; Jones, C D; Kandaswamy, J; Kreinick, D L; Magerkurth, A; Mahlke-Krüger, H; Meyer, T O; Mistry, N B; Nordberg, E; Palmer, M; Patterson, J R; Peterson, D; Pivarski, J; Riley, D; Sadoff, A J; Schwarthoff, H; Shepherd, M R; Thayer, J G; Urner, D; Valant-Spaight, B; Viehhauser, G; Warburton, A; Weinberger, M; Athar, S B; Avery, P; Stoeck, H; Yelton, J

2002-11-25

Using 13.53 fb(-1) of CLEO data, we have measured the ratios of the branching fractions R(+)(e),R(+)(mu) and the combined branching fraction ratio R(+)(l), defined by R(+)(l)=[B(D+-->K(*0)l(+)nu(l))]/[B(D+-->K-pi(+)pi(+))]. We find R(+)(e)=0.74+/-0.04+/-0.05, R(+)(mu)=0.72+/-0.10+/-0.05, and R(+)(l)=0.74+/-0.04+/-0.05, where the first and second errors are statistical and systematic, respectively. The known branching fraction B(D+-->K-pi(+)pi(+)) leads to B(D+-->K(*0)e(+)nu(e))=(6.7+/-0.4+/-0.5+/-0.4)%, B(D+-->K(*0)mu(+)nu(mu))=(6.5+/-0.9+/-0.5+/-0.4)%, and B(D+-->K(*0)l(+)nu(l))=(6.7+/-0.4+/-0.5+/-0.4)%, where the third error is due to the uncertainty in B(D+-->K-pi(+)pi(+)).

34 CFR 366.27 - What selection criteria does the Secretary use?

Code of Federal Regulations, 2012 CFR

2012-07-01

... race, color, national origin, gender, age, or disability; and (v) The extent to which the applicant, as... racial or ethnic minority groups; (B) Women; (C) Persons with disabilities; and (D) Elderly individuals... are selected without regard to race, color, national origin, gender, age, or disability; and (6) A...

40 CFR 73.2 - Applicability.

Code of Federal Regulations, 2013 CFR

2013-07-01

...) Any owner of an affected unit who may apply to receive allowances under the Energy Conservation and Renewable Energy Reserve Program established in accordance with section 404(f) of the Act; (d) Any small... affected units pursuant to § 72.6 of this chapter; (b) Any new independent power producer as defined in...

40 CFR 73.2 - Applicability.

Code of Federal Regulations, 2011 CFR

2011-07-01

...) Any owner of an affected unit who may apply to receive allowances under the Energy Conservation and Renewable Energy Reserve Program established in accordance with section 404(f) of the Act; (d) Any small... affected units pursuant to § 72.6 of this chapter; (b) Any new independent power producer as defined in...

40 CFR 73.2 - Applicability.

Code of Federal Regulations, 2014 CFR

2014-07-01

...) Any owner of an affected unit who may apply to receive allowances under the Energy Conservation and Renewable Energy Reserve Program established in accordance with section 404(f) of the Act; (d) Any small... affected units pursuant to § 72.6 of this chapter; (b) Any new independent power producer as defined in...

40 CFR 73.2 - Applicability.

Code of Federal Regulations, 2012 CFR

2012-07-01

...) Any owner of an affected unit who may apply to receive allowances under the Energy Conservation and Renewable Energy Reserve Program established in accordance with section 404(f) of the Act; (d) Any small... affected units pursuant to § 72.6 of this chapter; (b) Any new independent power producer as defined in...

40 CFR 73.2 - Applicability.

Code of Federal Regulations, 2010 CFR

2010-07-01

...) Any owner of an affected unit who may apply to receive allowances under the Energy Conservation and Renewable Energy Reserve Program established in accordance with section 404(f) of the Act; (d) Any small... affected units pursuant to § 72.6 of this chapter; (b) Any new independent power producer as defined in...

Two-dimensional B-C-O alloys: a promising class of 2D materials for electronic devices.

PubMed

Zhou, Si; Zhao, Jijun

2016-04-28

Graphene, a superior 2D material with high carrier mobility, has limited application in electronic devices due to zero band gap. In this regard, boron and nitrogen atoms have been integrated into the graphene lattice to fabricate 2D semiconducting heterostructures. It is an intriguing question whether oxygen can, as a replacement of nitrogen, enter the sp2 honeycomb lattice and form stable B-C-O monolayer structures. Here we explore the atomic structures, energetic and thermodynamic stability, and electronic properties of various 2D B-C-O alloys using first-principles calculations. Our results show that oxygen can be stably incorporated into the graphene lattice by bonding with boron. The B and O species favor forming alternate patterns into the chain- or ring-like structures embedded in the pristine graphene regions. These B-C-O hybrid sheets can be either metals or semiconductors depending on the B : O ratio. The semiconducting (B2O)nCm and (B6O3)nCm phases exist under the B- and O-rich conditions, and possess a tunable band gap of 1.0-3.8 eV and high carrier mobility, retaining ∼1000 cm2 V(-1) s(-1) even for half coverage of B and O atoms. These B-C-O alloys form a new class of 2D materials that are promising candidates for high-speed electronic devices.

NASA ER-2 Doppler radar reflectivity calibration for the CAMEX project

NASA Technical Reports Server (NTRS)

Caylor, I. J.; Heymsfield, G. M.; Bidwell, S. W.; Ameen, S.

1994-01-01

The NASA ER-2 Doppler radar (EDOP) was flown aboard the ER-2 high-altitude aircraft in September and October 1993 for the Convection and Moisture Experiment. During these flights, the first reliable reflectivity observations were performed with the EDOP instrument. This report details the procedure used to convert real-time engineering data into calibrated radar reflectivity. Application of the calibration results produces good agreement between the EDOP nadir pointing reflectivity and ground truth provided by a National Weather Service WSR-88D radar. The rms deviation between WSR-88D and EDOP is 6.9 dB, while measurements of the ocean surface backscatter coefficient are less than 3 dB from reported scatterometer coefficients. After an initial 30-minute period required for the instrument to reach thermal equilibrium, the radar is stable to better than 0.25 dB during flight. The range performance of EDOP shows excellent agreement with aircraft altimeter and meteorological sounding data.

Synthesis of geophysical data (phase V, deliverable 55): Chapter B in Second projet de renforcement institutionnel du secteur minier de la République Islamique de Mauritanie (PRISM-II)

USGS Publications Warehouse

Finn, Carol A.; Anderson, Eric D.

2015-01-01

Aeromagnetic and radiometric data were used to map shallow Precambrian basement lithology and structure and determine the depth to magnetic basement, which in most cases, corresponds to the depth to crystalline basement of interest for mineral exploration. These depths, along with those determined from gravity data, help identify basins with hydrologic potential. In addition, the magnetic data were used to identify buried Precambrian rocks of unknown affinity.

Chemical Stockpile Disposal Program. Risk Analysis of the Continued Storage of Chemical Munitions

DTIC Science & Technology

1987-08-01

Grass Army Depot LIC liquid incinerator LPF leakers processing facility LPG liquified propane gas MD)B munitions demilitarization building"I 1DIA mu...screening process , con- sidering both frequency and magnitude of agent release, are included in the deliverables of this project. S.1.3. Scove of Study...simplistic terms the PRA process focuses on answering the fol- •• loving three basic questions: 1. Wh.t can go wrong? 2. How frequently is it expected to

The role of nonmagnetic d{sup 0} vs. d{sup 10}B-type cations on the magnetic exchange interactions in osmium double perovskites

DOE Office of Scientific and Technical Information (OSTI.GOV)

Feng, Hai L., E-mail: Hai.Feng@cpfs.mpg.de; Yamaura, Kazunari; Tjeng, Liu Hao

Polycrystalline samples of double perovskites Ba{sub 2}BOsO{sub 6} (B=Sc, Y, In) were synthesized by solid state reactions. They adopt the cubic double perovskite structures (space group, Fm-3m) with ordered B and Os arrangements. Ba{sub 2}BOsO{sub 6} (B=Sc, Y, In) show antiferromagnetic transitions at 93 K, 69 K, and 28 K, respectively. The Weiss-temperatures are −590 K for Ba{sub 2}ScOsO{sub 6}, −571 K for Ba{sub 2}YOsO{sub 6}, and −155 K for Ba{sub 2}InOsO{sub 6}. Sc{sup 3+} and Y{sup 3+} have the open-shell d{sup 0} electronic configuration, while In{sup 3+} has the closed-shell d{sup 10}. This indicates that a d{sup 0} B-typemore » cation induces stronger overall magnetic exchange interactions in comparison to a d{sup 10}. Comparison of Ba{sub 2}BOsO{sub 6} (B=Sc, Y, In) to their Sr and Ca analogues shows that the structural distortions weaken the overall magnetic exchange interactions. - Graphical abstract: Magnetic properties of osmium double perovskites Ba{sub 2}BOsO{sub 6} (B=Sc, Y, In) were studied. Comparison of Ba{sub 2}BOsO{sub 6}indicates that a d{sup 0} B-type cation induces stronger overall magnetic exchange interactions in comparison to a d{sup 10}. - Highlights: • Magnetic properties of double perovskites Ba{sub 2}BOsO{sub 6} (B=Sc, Y, In) were studied. • A d{sup 0}B-type cation induces stronger magnetic interactions than a d{sup 10}. • Structural distortions weaken the overall Os{sup 5+}-Os{sup 5+} magnetic interactions.« less

The efficacy of unilateral bone-anchored hearing devices in Chinese Mandarin-speaking patients with bilateral aural atresia.

PubMed

Fan, Yue; Zhang, Ying; Wang, Pu; Wang, Zhen; Zhu, Xiaoli; Yang, Hua; Chen, Xiaowei

2014-04-01

The bone-anchored hearing device (BAHD) was not introduced in China until 2010. To our knowledge, this is the first study to assess the efficacy of Chinese Mandarin-speaking patients with bilateral aural atresia. To evaluate the speech recognition of Chinese Mandarin-speaking patients with BAHDs as well as patients' satisfaction using 2 questionnaires. A retrospective case review of 16 patients with bilateral aural atresia conducted at a tertiary referral center. A BAHD was implanted during auricle reconstruction surgery or after the auricle was rebuilt. A surgical method to combine the BAHD implantation with the second stage of ear reconstruction was introduced. Speech audiometry test and mean pure-tone threshold results were compared among patients with unaided hearing and those with BAHDs. Scores from the BAHD user questionnaire and Glasgow Children's Benefit Inventory (GCBI) were used to measure patients' satisfaction and subjective health benefit. The mean (SD) speech discrimination scores measured in a sound field with a presentation level of 45 dB HL (hearing level) were 6.7% (7.4%) unaided and 86.5% (4.4%) with a BAHD. Scores with a presentation level of 65 dB HL were 56.5% (7.4%) unaided and 90.1% (3.4%) with a BAHD. The speech reception threshold was 60.6 (7.5) dB HL unaided and 24.7 (5.0) dB HL with a BAHD. The mean (SD) pure-tone threshold of the patients was 61.6 (7.8) dB HL unaided and 23.8 (5.9) dB HL with a BAHD. The BAHD application questionnaire demonstrated excellent patient satisfaction. The mean (SD) benefit score of GCBI was 45.6 (14.4). For aural atresia, the BAHD has been one of the most reliable methods of auditory rehabilitation. It can improve the patient's word recognition performance and quality of life. The technique of BAHD implantation combined with auricular reconstruction in a 2-stages-in-1 surgery and the modified incision of patients with reconstructed auricle proved to be safe and effective.

Advanced Wear-resistant Nanocomposites for Increased Energy Efficiency

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cook, B. A.; Harringa, J. L.; Russel, A. M.

This report summarizes the work performed by an Ames-led project team under a 4-year DOE-ITP sponsored project titled, 'Advanced Wear-resistant Nanocomposites for Increased Energy Efficiency.' The Report serves as the project deliverable for the CPS agreement number 15015. The purpose of this project was to develop and commercialize a family of lightweight, bulk composite materials that are highly resistant to degradation by erosive and abrasive wear. These materials, based on AlMgB{sub 14}, are projected to save over 30 TBtu of energy per year when fully implemented in industrial applications, with the associated environmental benefits of eliminating the burning of 1.5more » M tons/yr of coal and averting the release of 4.2 M tons/yr of CO{sub 2} into the air. This program targeted applications in the mining, drilling, machining, and dry erosion applications as key platforms for initial commercialization, which includes some of the most severe wear conditions in industry. Production-scale manufacturing of this technology has begun through a start-up company, NewTech Ceramics (NTC). This project included providing technical support to NTC in order to facilitate cost-effective mass production of the wear-resistant boride components. Resolution of issues related to processing scale-up, reduction in energy intensity during processing, and improving the quality and performance of the composites, without adding to the cost of processing were among the primary technical focus areas of this program. Compositional refinements were also investigated in order to achieve the maximum wear resistance. In addition, synthesis of large-scale, single-phase AlMgB{sub 14} powder was conducted for use as PVD sputtering targets for nanocoating applications.« less

Derivations of a Prime Ring Which Satisfy a Polynomial Identity.

DTIC Science & Technology

1983-01-01

that R is commutative and prime, and present three minor but interesting results. We will see Lemma 3.5 again in Chapter 4. One should compare Lemmas 3.6...such that (6ztyy - yzt6y) # 0 and. (Xztyy - yztAy) # 0. By Lemna 3.8, X - d6 for some d E C. Therefore, y - aX + bS - a(dS) + bW - (ad + b)d and

Multifunctional paper strip based on GO-veiled Ag nanoparticles with highly SERS sensitive and deliverable properties for high-performance molecular detection.

PubMed

Yang, Cheng; Xu, Yuanyuan; Wang, Minghong; Li, Tianming; Huo, Yanyan; Yang, Chuanxi; Man, Baoyuan

2018-04-16

The development of paper-based SERS substrates that can allow multi-component detection in real-word scenarios is of great value for applications in molecule detection under complex conditions. Here, a multifunctional SERS-based paper sensing substrate has been developed through the uniform patterning of high-density arrays of GO-isolated Ag nanoparticles on the hydrophilic porous cellulose paper strip (GO@AgNP@paper). Wet-chemical synthesis was used to provide the cover of SERS hot spots on any part of the paper, not just limited surface deposition. In virtue of the inherent ability of paper to deliver analytes by the capillary force, the detection ability of the GO@AgNP@paper substrate was greatly promoted, allowing as low as 10 -19 M R6G detection from microliter-volume (50 μL) samples. For the components with different polarity, the paper substrate can be used as an all-in-one machine to achieve the integration of separation and high-sensitive detection for ultralow mixture components, which improves the practical application value of SERS-based paper devices.

Ultra-wideband ladder filter using SH(0) plate wave in thin LiNbO(3) plate and its application to tunable filter.

PubMed

Kadota, Michio; Tanaka, Shuji

2015-05-01

A cognitive radio terminal using vacant frequency bands of digital TV (DTV) channels, i.e., TV white space, strongly requires a compact tunable filter covering a wide frequency range of the DTV band (470 to 710 MHz in Japan). In this study, a T-type ladder filter using ultra-wideband shear horizontal mode plate wave resonators was fabricated, and a low peak insertion loss of 0.8 dB and an ultra-large 6 dB bandwidth of 240 MHz (41%) were measured in the DTV band. In addition, bandpass filters with different center frequencies of 502 and 653 MHz at 6 dB attenuation were numerically synthesized based on the same T-type ladder filter in conjunction with band rejection filters with different frequencies. The results suggest that the combination of the wideband T-type ladder filter and the band rejection filters connected with variable capacitors enables a tunable filter with large tunability of frequency and bandwidth as well as large rejection at the adjacent channels of an available TV white space.

Fine tuning the emission wavelengths of the 7-hydroxy-1-indanone based nano-structure dyes: Near-infrared (NIR) dual emission generation with large stokes shifts

NASA Astrophysics Data System (ADS)

Roohi, Hossein; Alizadeh, Parvaneh

2018-05-01

Near-infrared (NIR) fluorescent dyes have recently gained special attention due to their applications to use as molecular probes for imaging of biological targets and sensitive determination. In this study, photophysical properties of the 7-hydroxy-1-indanone based fluorophors A1, A2, A3, B1, B2 and 3R-B2 (R = CF3, NH2, NO2 and OMe) in the gas and three solution phases were probed using TD-DFT method at PBE0/6-311++G(d,p) and M06-2X/6-311++G(d,p) levels of theory. In addition to structural and photophysical properties as well as ESIPT mechanism of all mentioned molecules, the FC and relaxed potential energy surfaces of B2 and 3R-B2 (R = CF3 and NH2) molecules were explored in gas phase and acetonitrile, cyclohexane and water solvents. It is predicted that the A1, A3 and 3R-B2 chromophores afford normal (615-670 nm) and NIR fluorescence emissions (770-940 nm; biological window) with the large Stokes shifts of >160 and >300 nm, respectively. A good aggrement was found between theoretical and experimental results. In sum, these new types of dyes may render the new approaches for the development of the most efficient NIR fluorescent probes for enhanced image contrast and optimal apparent brightness in biological applications.

Medicinal foodstuffs. XXVII. Saponin constituents of gotu kola (2): structures of new ursane- and oleanane-type triterpene oligoglycosides, centellasaponins B, C, and D, from Centella asiatica cultivated in Sri Lanka.

PubMed

Matsuda, H; Morikawa, T; Ueda, H; Yoshikawa, M

2001-10-01

Ursane- and oleanane-type triterpene oligoglycosides, centellasaponins B, C, and D, were isolated from the aerial parts of Centella asiatica (L.) Urban cultivated in Sri Lanka together with madecassoside, asiaticoside, asiaticoside B, and sceffoleoside A. The chemical structures of centellasaponins B, C, and D were determined on the basis of chemical and physicochemical evidence to be madecassic acid 28-O-beta-D-glucopyranosyl(1-->6)-beta-D-glucopyranoside, madasiatic acid 28-O-alpha-L-rhamnopyranosyl(1-->4)-beta-D-glucopyranosyl(1-->6)-beta-D-glucopyranoside, and 3beta,6beta,23-trihydroxyolean-12-en-28-oic acid 28-O-alpha-L-rhamnopyranosyl(1-->4)-beta-D-glucopyranosyl(1-->6)-beta-D-glucopyranoside, respectively.

Application of Detailed Chemical Kinetics to Combustion Instability Modeling

DTIC Science & Technology

2016-01-04

Modeling 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Harvazinski, Matt; Talley, Doug; Sankaran, Venke 5d. PROJECT...Chemical Kinetics to Combustion Instability Modeling Matt Harvazinski, Doug Talley, Venke Sankaran Air Force Research Laboratory Edwards AFB, CA...distribution unlimited. 3 Prior Work – Kinetics Used • Simulations : 1) 3D real geometry 2) Unsteady 3) Long run-times 4) Coupled physics • 1- 4

"Lollipop-shaped" high-sensitivity Microelectromechanical Systems vector hydrophone based on Parylene encapsulation

NASA Astrophysics Data System (ADS)

Liu, Yuan; Wang, Renxin; Zhang, Guojun; Du, Jin; Zhao, Long; Xue, Chenyang; Zhang, Wendong; Liu, Jun

2015-07-01

This paper presents methods of promoting the sensitivity of Microelectromechanical Systems (MEMS) vector hydrophone by increasing the sensing area of cilium and perfect insulative Parylene membrane. First, a low-density sphere is integrated with the cilium to compose a "lollipop shape," which can considerably increase the sensing area. A mathematic model on the sensitivity of the "lollipop-shaped" MEMS vector hydrophone is presented, and the influences of different structural parameters on the sensitivity are analyzed via simulation. Second, the MEMS vector hydrophone is encapsulated through the conformal deposition of insulative Parylene membrane, which enables underwater acoustic monitoring without any typed sound-transparent encapsulation. Finally, the characterization results demonstrate that the sensitivity reaches up to -183 dB (500 Hz 0dB at 1 V/ μPa ), which is increased by more than 10 dB, comparing with the previous cilium-shaped MEMS vector hydrophone. Besides, the frequency response takes on a sensitivity increment of 6 dB per octave. The working frequency band is 20-500 Hz and the concave point depth of 8-shaped directivity is beyond 30 dB, indicating that the hydrophone is promising in underwater acoustic application.

45 CFR Appendix A to Part 13 - Appendix A to Part 13

Code of Federal Regulations, 2012 CFR

2012-10-01

...-7a(c)(2); 1320b-10(c); 1395i-3(b)(3)(B)(ii), (g)(2)(A)(i); 1395l (h)(5)(D), (i)(6); 1395m(a)(11)(A), (a)(18), (b)(5)(C), (j)(2)(A)(iii); 1395u(j)(2), (k), (l )(3), (m)(3), (n)(3), (p)(3)(A); 1395y(b)(3)(C), (b)(6)(B); 1395cc(g); 1395dd(d)(1)(A), (B); 1395mm(i)(6)(B); 1395nn(g)(3), (4); 1395ss(d...

Responsive Plasma Polymerized Ultrathin Nanocomposite Films

DTIC Science & Technology

2012-01-01

29 74 32 75 Ab so rb an ce (a .u .) Wavenumber, cm-1 pNIPAAM A B C D E Fig . 2. FTIR spectra of A) NIPAAM monomer B) Spun- cast P-NIPAAM film and...self- actuating response to specific stimuli are desirable in a wide range of applications including thermalandchemical sensing, tunableoptics...targeteddrug delivery, switchable surfaces and micro actuators [1e6]. Designing materials which are capable of generating a response from the stim- ulus

Assessment Report Sandia National Laboratories Fuel Cycle Technologies Quality Assurance Evaluation of FY15 SNL FCT M2 Milestone Deliverables

DOE Office of Scientific and Technical Information (OSTI.GOV)

Appel, Gordon John

Sandia National Laboratories (SNL) Fuel Cycle Technologies (FCT) program activities are conducted in accordance with FCT Quality Assurance Program Document (FCT-QAPD) requirements. The FCT-QAPD interfaces with SNL approved Quality Assurance Program Description (SNL-QAPD) as explained in the Sandia National Laboratories QA Program Interface Document for FCT Activities (Interface Document). This plan describes SNL's FY16 assessment of SNL's FY15 FCT M2 milestone deliverable's compliance with program QA requirements, including SNL R&A requirements. The assessment is intended to confirm that SNL's FY15 milestone deliverables contain the appropriate authenticated review documentation and that there is a copy marked with SNL R&A numbers.

Improving the color of bulgur: new industrial applications of tempering and UV/sun-light treatments.

PubMed

Balci, Fatih; Bayram, Mustafa

2015-09-01

Color (CIE b*; yellowness) is an important parameter for bulgur quality. Color of bulgur is mainly due to natural pigments (carotenoids) that are present at different levels in wheat. In order to increase the customer acceptability, the producers try to obtain yellowish color in bulgur. In this study, two different tempering methods (spray and steam) were used before sun and UV- light polishing applications. Sun and UV-light were applied to tempered bulgur for 12, 24, 36, 48, 60 and 72 h. Moisture content (%, d.b.), ash content (%, d.b.), protein content (%, d.b.), total carotenoid content in terms of lutein equivalent (TCC) and color values (CIE L*; lightness, CIE b*; yellowness, CIE a*; redness and CIE YI; yellowness index) were determined. It was found that UV-light was more effective (P < 0.05) on the CIE L* and CIE b* values compared to sunlight. Both tempering methods were significantly (P < 0.05) increased the CIE L*, CIE b* and CIE YI values. Steam tempering has a significant effect (P < 0.05) on the CIE b* values as well as UV and time of UV exposure. The highest value of TCC i.e. 6.31 μg/g was obtained by using spray tempering and UV-light exposure. As a conclusion, as proposed methods steam tempering and UV-light have an obvious positive effect on the color of bulgur.

A 12b 200kS/s 0.52mA 0.47mm2 Algorithmic A/D Converter for MEMS Applications

NASA Astrophysics Data System (ADS)

Kim, Young-Ju; Choi, Hee-Cheol; Lee, Seung-Hoon; Cho, Dongil “Dan”

This work describes a 12b 200kS/s 0.52mA 0.47mm2 ADC for sensor applications such as motor control, 3-phase power control, and CMOS image sensors simultaneously requiring ultra-low power and small size. The proposed ADC is based on the conventional algorithmic architecture with a recycling signal path to optimize sampling rate, resolution, chip area, and power consumption. The input SHA with eight input channels employs a folded-cascode amplifier to achieve a required DC gain and a high phase margin. A 3-D fully symmetric layout with critical signal lines shielded reduces the capacitor and device mismatch of the multiplying D/A converter while switched-bias power-reduction circuits minimize the power consumption of analog amplifiers. Current and voltage references are integrated on chip with optional off-chip voltage references for low glitch noise. The down-sampling clock signal selects the sampling rate of 200kS/s and 10kS/s with a further reduced power depending on applications. The prototype ADC in a 0.18μm n-well 1P6M CMOS process demonstrates a maximum measured DNL and INL within 0.40 LSB and 1.97 LSB and shows a maximum SNDR and SFDR of 55dB and 70dB at all sampling frequencies up to 200kS/s, respectively. The ADC occupies an active die area of 0.47mm2 and consumes 0.94mW at 200kS/s and 0.63mW at 10kS/s with a 1.8V supply.

3-D airborne ultrasound synthetic aperture imaging based on capacitive micromachined ultrasonic transducers.

PubMed

Park, Kwan Kyu; Khuri-Yakub, Butrus T

2013-09-01

In this paper, we present an airborne 3-D volumetric imaging system based on capacitive micromachined ultrasonic transducers (CMUTs). For this purpose we fabricated 89-kHz CMUTs where each CMUT is made of a circular single-crystal silicon plate with a radius of 1mm and a thickness of 20 μm, which is actuated by electrostatic force through a 20-μm vacuum gap. The measured transmit sensitivity at 300-V DC bias is 14.6 Pa/V and 24.2 Pa/V, when excited by a 30-cycle burst and a continuous wave, respectively. The measured receive sensitivity at 300-V DC bias is 16.6 mV/Pa (-35.6 dB re 1 V/Pa) for a 30-cycle burst. A 26×26 2-D array was implemented by mechanical scanning a co-located transmitter and receiver using the classic synthetic aperture (CSA) method. The measurement of a 1.6λ-size target at a distance of 500 mm presented a lateral resolution of 3.17° and also showed good agreement with the theoretical point spread function. The 3-D imaging of two plates at a distance of 350 mm and 400 mm was constructed to exhibit the capability of the imaging system. This study experimentally demonstrates that a 2-D CMUT array can be used for practical 3-D imaging applications in air, such as a human-machine interface. Copyright © 2013 Elsevier B.V. All rights reserved.

17 CFR 240.3a68-4 - Regulation of mixed swaps.

Code of Federal Regulations, 2013 CFR

2013-04-01

....S.C. 78c(a)(68)(D)). (b) Regulation of bilateral uncleared mixed swaps entered into by dually...(f) and 12; (B) Enforcement: 7 U.S.C. 2(a)(1)(B), 6(b), 6b, 6c, 6s(h)(1)(A), 6s(h)(4)(A), 9, 13b, 13a-1, 13a-2, 13, 13c(a), 13c(b), 15 and 26; (C) Reporting to a swap data repository: 7 U.S.C. 6r; (D...

Scaled Quantum Mechanical scale factors for vibrational calculations using alternate polarized and augmented basis sets with the B3LYP density functional calculation model

NASA Astrophysics Data System (ADS)

Legler, C. R.; Brown, N. R.; Dunbar, R. A.; Harness, M. D.; Nguyen, K.; Oyewole, O.; Collier, W. B.

2015-06-01

The Scaled Quantum Mechanical (SQM) method of scaling calculated force constants to predict theoretically calculated vibrational frequencies is expanded to include a broad array of polarized and augmented basis sets based on the split valence 6-31G and 6-311G basis sets with the B3LYP density functional. Pulay's original choice of a single polarized 6-31G(d) basis coupled with a B3LYP functional remains the most computationally economical choice for scaled frequency calculations. But it can be improved upon with additional polarization functions and added diffuse functions for complex molecular systems. The new scale factors for the B3LYP density functional and the 6-31G, 6-31G(d), 6-31G(d,p), 6-31G+(d,p), 6-31G++(d,p), 6-311G, 6-311G(d), 6-311G(d,p), 6-311G+(d,p), 6-311G++(d,p), 6-311G(2d,p), 6-311G++(2d,p), 6-311G++(df,p) basis sets are shown. The double d polarized models did not perform as well and the source of the decreased accuracy was investigated. An alternate system of generating internal coordinates that uses the out-of plane wagging coordinate whenever it is possible; makes vibrational assignments via potential energy distributions more meaningful. Automated software to produce SQM scaled vibrational calculations from different molecular orbital packages is presented.

Microcomputer-Assisted Flow-Through ASV System.

DTIC Science & Technology

1979-09-01

89 03 A ADCA #$03 0037 7A 0300 D DEC SAVz1 0042 26 F6 003A DN! THOULP 0044 39 XITBIN RTS * XDTF BCDBIN 19 or iko. 302 SCUE j CD To BINARY CONVERSION...TIMFLG 0006 BD 0330 A SKIP75 JSR CLOCK GET TINE AND DIPLAY 0009 B6 0300 A LDAA P5BC CHECK IF "GO" PUSHED OOOC 2B 02 0013 BMI SKIP75 YES- RTS 000E 20 F6 ...405 RESET STACK PT 0003 B7 0002 D STAA TP 0006 F7 0083 D STAB TP+1 0009 B6 0018 D LDAA IPHI CALCULATE (IP-IV) FOR OSOC F6 0319 D LDAB IPLO CD 000F FO

Planar dicyclic B{sub 6}S{sub 6}, B{sub 6}S{sub 6}{sup −}, and B{sub 6}S{sub 6}{sup 2−} clusters: Boron sulfide analogues of naphthalene

DOE Office of Scientific and Technical Information (OSTI.GOV)

Li, Da-Zhi; Bai, Hui; Ou, Ting

2015-01-07

Inorganic analogues of hydrocarbons or polycyclic aromatic hydrocarbons (PAHs) are of current interest in chemistry. Based upon global structural searches and B3LYP and CCSD(T) calculations, we present herein the perfectly planar dicyclic boron sulfide clusters: D{sub 2h} B{sub 6}S{sub 6} (1, {sup 1}A{sub g}), D{sub 2h} B{sub 6}S{sub 6}{sup −} (2, {sup 2}B{sub 3u}), and D{sub 2h} B{sub 6}S{sub 6}{sup 2−} (3, {sup 1}A{sub g}). These are the global minima of the systems, being at least 0.73, 0.81, and 0.53 eV lower in energy, respectively, than their alternative isomers at the CCSD(T) level. The D{sub 2h} structures feature twin B{submore » 3}S{sub 2} five-membered rings, which are fused together via a B{sub 2} unit and terminated by two BS groups. Bonding analyses show that the closed-shell B{sub 6}S{sub 6}{sup 2−} (3) cluster possesses 10 delocalized π electrons, closely analogous to the bonding pattern of the aromatic naphthalene C{sub 10}H{sub 8}. The B{sub 6}S{sub 6}{sup −} (2) and B{sub 6}S{sub 6} (1) species are readily obtained upon removal of one or two π electrons from B{sub 6}S{sub 6}{sup 2−} (3). The results build a new analogous relationship between boron sulfide clusters and their PAH counterparts. The B{sub 6}S{sub 6}{sup −} (2) monoanion and B{sub 6}S{sub 6}{sup 2−} (3) dianion can be effectively stabilized in neutral LiB{sub 6}S{sub 6} and Li{sub 2}B{sub 6}S{sub 6} salts, respectively.« less

78 FR 6845 - Application of Rhoades Aviation, Inc. d/b/a Transair for Certificate Authority

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-31

... DEPARTMENT OF TRANSPORTATION Office of the Secretary Application of Rhoades Aviation, Inc. d/b/a... Transportation is directing all interested persons to show cause why it should not issue orders finding Rhoades Aviation, Inc. d/b/a Transair, fit, willing, and able, and to provide interstate and foreign charter air...

77 FR 34122 - Application of Sun Air Express, LLC, d/b/a Sun Air International for Commuter Authority

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-08

... DEPARTMENT OF TRANSPORTATION Office of the Secretary [Docket DOT-OST-2011-0169] Application of Sun Air Express, LLC, d/b/a Sun Air International for Commuter Authority AGENCY: Department of... order finding Sun Air Express, LLC d/b/a Sun Air International fit, willing, and able, and awarding it...

77 FR 43135 - Application of City Wings, Inc. D/B/A Seaflight for Commuter Authority

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-23

... DEPARTMENT OF TRANSPORTATION [Docket DOT-OST-2010-0263] Application of City Wings, Inc. D/B/A... cause why it should not issue an order finding City Wings, Inc. d/b/a Seaflight fit, willing, and able... be served upon the parties listed in Attachment A to the order. FOR FURTHER INFORMATION CONTACT...

NMR, FT-IR, Raman and UV-Vis spectroscopic investigation and DFT study of 6-Bromo-3-Pyridinyl Boronic Acid

NASA Astrophysics Data System (ADS)

Dikmen, Gökhan; Alver, Özgür

2015-11-01

Possible stable conformers and geometrical molecular structures of 6-Bromo-3-Pyridinyl Boronic acid (6B3PBA; C5H5BBrNO2) were studied experimentally and theoretically using FT-IR and Raman spectroscopic methods. FT-IR and Raman spectra were recorded in the region of 4000-400 cm-1 and 3700-400 cm-1, respectively. The structural properties were investigated further, using 1H, 13C, 1H coupled 13C, HETCOR, COSY and APT NMR techniques. The optimized geometric structures were searched by Becke-3-Lee-Yang-Parr (B3LYP) hybrid density functional theory method with 6-311++G(d, p) basis set. Vibrational wavenumbers of 6B3PBA were calculated whereby B3LYP density functional methods including 6-311++G(d, p), 6-311G(d, p), 6-311G(d), 6-31G(d, p) and 6-31G(d) basis sets. The comparison of the experimentally and theoretically obtained results using mean absolute error and experimental versus calculated correlation coefficients for the vibrational wavenumbers indicates that B3LYP method with 6-311++G(d, p) gives more satisfactory results for predicting vibrational wavenumbers when compared to the 6-311G(d, p), 6-311G(d), 6-31G(d, p) and 6-31G(d) basis sets. However, this method and none of the mentioned methods here seem suitable for the calculations of OH stretching modes, most likely because increasing unharmonicity in the high wave number region and possible intra and inter molecular interactions at OH edges lead some deviations between experimental and theoretical results. Moreover, reliable vibrational assignments were made on the basis of total energy distribution (TED) calculated using scaled quantum mechanical (SQM) method.

Technical support plan for HANDI 2000 business management system

DOE Office of Scientific and Technical Information (OSTI.GOV)

Adams, D.E.

The Hanford Data Integration 2000 (HANDI 2000) Project will result in an integrated and comprehensive set of functional applications containing core information necessary to support the Project Hanford Management Contract. It is based on the Commercial-Off-The-Shelf (COTS) product solution with commercially proven business processes. The PassPort (PP) software is an integrated application for Accounts Payable, Contract Management, Inventory Management, and Purchasing. The PeopleSoft (PS) software is an integrated application for General Ledger, Project Costing, Human Resources, Payroll, Benefits, and Training. The implementation of this set of products, as the first deliverable of the HAND1 2000 Project, is referred to asmore » Business Management System (BMS) and Chemical Management.« less

Alteration of the brain morphology and the response to the acute stress in the recombinant mouse lines with different predisposition to catalepsy.

PubMed

Kulikova, E A; Bazovkina, D V; Antonov, Y V; Akulov, A E; Kulikov, A V; Kondaurova, E M

2017-04-01

Catalepsy is an inability to correct an externally imposed awkward posture; it is associated with schizophrenia and depression in human. We created new recombinant B6.CBA-D13Mit76C and B6.CBA-D13Mit76B mouse lines on the C57Bl/6 genome, carrying the 102.73-110.56Mbp fragment of chromosome 13 derived from the catalepsy-prone CBA strain and catalepsy-resistant C57BL/6 strain, respectively. We compared the behavior and brain morphology (11.7T BioSpec 117/16 USR tomograph, Germany) in these lines. The effects of acute emotional stress on corticosterone's level in the blood and mRNA expression of Bdnf and Arc genes in the brain were investigated. The B6.CBA-D13Mit76B mice were non-cataleptic, while about 17% of B6.CBA-D13Mit76C mice demonstrated catalepsy-like immobility. No difference between these lines was revealed in the open field and social interaction tests. In the Morris water maze test, both lines effectively found the platform on the fourth day; however B6.CBA-D13Mit76B mice achieved significantly better results than cataleptic-prone animals. B6.CBA-D13Mit76C mice were characterized by decreased volume of the total brain and reduced sizes of striatum, cerebellum and pituitary gland. The both lines showed the similar basal and stress-induced levels of corticosterone, while the brain expression of Bdnf and Arc genes was more vulnerable to stress in the catalepsy-prone B6.CBA-D13Mit76C line. Copyright © 2016 Elsevier Ireland Ltd and Japan Neuroscience Society. All rights reserved.

DFT computational analysis of piracetam

NASA Astrophysics Data System (ADS)

Rajesh, P.; Gunasekaran, S.; Seshadri, S.; Gnanasambandan, T.

2014-11-01

Density functional theory calculation with B3LYP using 6-31G(d,p) and 6-31++G(d,p) basis set have been used to determine ground state molecular geometries. The first order hyperpolarizability (β0) and related properties (β, α0 and Δα) of piracetam is calculated using B3LYP/6-31G(d,p) method on the finite-field approach. The stability of molecule has been analyzed by using NBO/NLMO analysis. The calculation of first hyperpolarizability shows that the molecule is an attractive molecule for future applications in non-linear optics. Molecular electrostatic potential (MEP) at a point in the space around a molecule gives an indication of the net electrostatic effect produced at that point by the total charge distribution of the molecule. The calculated HOMO and LUMO energies show that charge transfer occurs within these molecules. Mulliken population analysis on atomic charge is also calculated. Because of vibrational analysis, the thermodynamic properties of the title compound at different temperatures have been calculated. Finally, the UV-Vis spectra and electronic absorption properties are explained and illustrated from the frontier molecular orbitals.

Control Improvisation with Application to Music

DTIC Science & Technology

2013-11-04

Control Improvisation with Application to Music Alexandre Donze Sophie Libkind Sanjit A. Seshia David Wessel Electrical Engineering and Computer...to Music 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7...domain of music . More speci cally, we consider the scenario of generating a monophonic Jazz melody (solo) on a given song harmonization. The music is

Design of inside cut von koch fractal UWB MIMO antenna

NASA Astrophysics Data System (ADS)

Tharani, V.; Shanmuga Priya, N.; Rajesh, A.

2017-11-01

An Inside Cut Hexagonal Von Koch fractal MIMO antenna is designed for UWB applications and its characteristics behaviour are studied. Self-comparative and space filling properties of Koch fractal structure are utilized in the antenna design which leads to the desired miniaturization and wideband characteristics. The hexagonal shaped Von Koch Fractal antenna with Defected Ground Structure (DGS) is designed on FR4 substrate with a compact size of 30mm x 20mm x 1.6mm. The antenna achieves a maximum of -44dB and -51dB at 7.1GHz for 1-element and 2-element case respectively.

TM grating coupler on low-loss LPCVD based Si3N4 waveguide platform

NASA Astrophysics Data System (ADS)

Dabos, G.; Manolis, A.; Giesecke, A. L.; Porschatis, C.; Chmielak, B.; Wahlbrink, T.; Pleros, N.; Tsiokos, D.

2017-12-01

We demonstrate, for the first time to our knowledge, a fully etched TM grating coupler for low-loss Low-Pressure-Chemical-Vapor-Deposition (LPCVD) based silicon nitride platform with a coupling loss of 6.5 dB at 1541 nm and a 1 dB bandwidth of 55 nm, addressing applications where TM polarization is a pre-requisite. The proposed GC and the 360 nm × 800 nm strip based Si3N4 waveguides have been fabricated by optical projection lithography using an i-line stepper tool enabling low-cost and mass manufacturing of photonic-integrated-circuits.

47 CFR 73.3564 - Acceptance of applications.

Code of Federal Regulations, 2013 CFR

2013-10-01

... in 47 U.S.C. 310(b), (C) Tower/antenna heights, (D) Effective radiated power, (E) Whether the antenna... 47 Telecommunication 4 2013-10-01 2013-10-01 false Acceptance of applications. 73.3564 Section 73...) Applicant's name and address, (B) Applicant's signature, (C) Principal community, (D) Channel or frequency...

47 CFR 73.3564 - Acceptance of applications.

Code of Federal Regulations, 2011 CFR

2011-10-01

... in 47 U.S.C. 310(b), (C) Tower/antenna heights, (D) Effective radiated power, (E) Whether the antenna... 47 Telecommunication 4 2011-10-01 2011-10-01 false Acceptance of applications. 73.3564 Section 73...) Applicant's name and address, (B) Applicant's signature, (C) Principal community, (D) Channel or frequency...

47 CFR 73.3564 - Acceptance of applications.

Code of Federal Regulations, 2014 CFR

2014-10-01

... in 47 U.S.C. 310(b), (C) Tower/antenna heights, (D) Effective radiated power, (E) Whether the antenna... 47 Telecommunication 4 2014-10-01 2014-10-01 false Acceptance of applications. 73.3564 Section 73...) Applicant's name and address, (B) Applicant's signature, (C) Principal community, (D) Channel or frequency...

47 CFR 73.3564 - Acceptance of applications.

Code of Federal Regulations, 2012 CFR

2012-10-01

... in 47 U.S.C. 310(b), (C) Tower/antenna heights, (D) Effective radiated power, (E) Whether the antenna... 47 Telecommunication 4 2012-10-01 2012-10-01 false Acceptance of applications. 73.3564 Section 73...) Applicant's name and address, (B) Applicant's signature, (C) Principal community, (D) Channel or frequency...

A seven-year review of measured hearing levels in male manual steelworkers with high initial thresholds

PubMed Central

Howell, R. W.

1978-01-01

ABSTRACT Audiometric records of 449 male manual steelworkers were reviewed to see whether the hearing of men with high initial threshold levels deteriorated more rapidly than that of those men with more normal thresholds when exposed to similar noise levels. Subjects were between 15 and 54 years old at the time of initial examination, and had a repeat audiogram 6-8 years later. They were classified into three occupational noise exposure groups: below 90 dB(A), 90-99 dB(A), and 100 dB(A) or over, without knowledge of their audiometric threshold levels, age, or aural history. Measurements at 0·5, 1, 2, 3, 4 and 6 kHz for the right ear were considered, first as the mean for all six frequencies, then for 0·5, 1 and 2 kHz only, and finally for 6 kHz only. After standardisation for age, it was found that those in the high initial threshold groups deteriorated no faster than the remainder of the series. At the 90-99 dB(A) noise exposure level, χ2 tests showed that the differences between the groups, in terms of mean measured hearing loss, were not significant at the 0·05 probability level. The age-standardised mean threshold shifts for the 0·5-6 kHz range of frequencies over the seven-year review period were 7·5, 8·7 and 7·1 dB at a noise exposure level of 100 dB(A) or more, for workers with an initial threshold level of <12 dB, 12-26 dB and > 26 dB respectively; for those exposed to noise of 90-99 dB(A) the corresponding mean shifts were 7·8, 6·8 and 7·3 dB respectively; while for those exposed to noise of less than 90 dB(A) the mean shifts were 6·2, 5·0 and 5·2 dB respectively. PMID:629886

Evaluating topologically diverse metal–organic frameworks for cryo-adsorbed hydrogen storage

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gómez-Gualdrón, Diego A.; Colón, Yamil J.; Zhang, Xu

Metal–organic frameworks (MOFs) are porous materials synthesized by combining inorganic and organic molecular building blocks into crystalline networks of distinct topologies. Due to the combinatorial possibilities, there are millions of possible MOF structures. Aiming to exploit their exceptional tunability, surface areas and pore volumes, researchers have investigated MOFs for storage of gaseous fuels such as hydrogen for over a decade, but a suitable MOF to store hydrogen at ambient conditions has not yet been found. Here, we sought to rapidly determine the viability of using MOFs for hydrogen storage at recently proposed, cryogenic operating conditions. We constructed a large andmore » structurally diverse set of 13 512 potential MOF structures based on 41 different topologies and used molecular simulation to determine MOF hydrogen deliverable capacities between 100 bar/77 K and 5 bar/160 K. The highest volumetric deliverable capacity was 57 g L-1 of MOF, which surpasses the 37 g L-1 of tank of the incumbent technology (compressing hydrogen to 700 bar at ambient temperature). To validate our in silico MOF construction method, we synthesized a new isoreticular family of MOFs (she-MOF-x series) based on the she topology, which is extremely rare among MOFs. To validate our hydrogen storage predictions, we activated and measured hydrogen adsorption on she-MOF-1 and NU-1103. The latter MOF showed outstanding stability and a good combination of volumetric and gravimetric performance, presenting 43.2 g L-1 of MOF and 12.6 wt% volumetric and gravimetric deliverable capacities, respectively.« less

High-Sensitivity Conjugated Polymer/Nanoparticle Nanocomposites for Infrared Sensor Applications

DTIC Science & Technology

2011-03-03

Performances of Photovoltaic devices base d on Thieno[3,4-c] pyrrole -4,6-dione-Based Donor-Acceptor Conjugated Polymers and CdSe Tetrapods Abstract: We...2-yl)thieno[3,2-b] thiophene and thieno[3,4-c] pyrrole -4,6-dione units. The AM1.5 power conversion efficiency of a photovoltaic device containing...photovoltaic devices because of their readily tunable electronic properties. The electron-deficient thieno[3,4-c] pyrrole -4,6-dione (TPD) moiety exhibits a

49 CFR 325.79 - Application of correction factors.

Code of Federal Regulations, 2014 CFR

2014-10-01

... microphone location point and the microphone target point is 60 feet (18.3 m) and that the measurement area... vehicle would be 87 dB(A), calculated as follows: 88 dB(A)Uncorrected average of readings −3 dB(A)Distance correction factor +2 dB(A)Ground surface correction factor _____ 87 dB(A)Corrected reading ...

49 CFR 325.79 - Application of correction factors.

Code of Federal Regulations, 2013 CFR

2013-10-01

... microphone location point and the microphone target point is 60 feet (18.3 m) and that the measurement area... vehicle would be 87 dB(A), calculated as follows: 88 dB(A)Uncorrected average of readings −3 dB(A)Distance correction factor +2 dB(A)Ground surface correction factor _____ 87 dB(A)Corrected reading ...

49 CFR 325.79 - Application of correction factors.

Code of Federal Regulations, 2012 CFR

2012-10-01

... microphone location point and the microphone target point is 60 feet (18.3 m) and that the measurement area... vehicle would be 87 dB(A), calculated as follows: 88 dB(A)Uncorrected average of readings −3 dB(A)Distance correction factor +2 dB(A)Ground surface correction factor _____ 87 dB(A)Corrected reading ...

49 CFR 538.9 - Dual fuel vehicle incentive.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 6 2011-10-01 2011-10-01 false Dual fuel vehicle incentive. 538.9 Section 538.9... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION MANUFACTURING INCENTIVES FOR ALTERNATIVE FUEL VEHICLES § 538.9 Dual fuel vehicle incentive. The application of 49 U.S.C. 32905(b) and (d) to qualifying dual fuel vehicles...

49 CFR 538.9 - Dual fuel vehicle incentive.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 6 2010-10-01 2010-10-01 false Dual fuel vehicle incentive. 538.9 Section 538.9... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION MANUFACTURING INCENTIVES FOR ALTERNATIVE FUEL VEHICLES § 538.9 Dual fuel vehicle incentive. The application of 49 U.S.C. 32905(b) and (d) to qualifying dual fuel vehicles...

49 CFR 538.9 - Dual fuel vehicle incentive.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 49 Transportation 6 2013-10-01 2013-10-01 false Dual fuel vehicle incentive. 538.9 Section 538.9... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION MANUFACTURING INCENTIVES FOR ALTERNATIVE FUEL VEHICLES § 538.9 Dual fuel vehicle incentive. The application of 49 U.S.C. 32905(b) and (d) to qualifying dual fuel vehicles...

48 CFR 8.404 - Use of Federal Supply Schedules.

Code of Federal Regulations, 2010 CFR

2010-10-01

... considered to be issued using full and open competition (see 6.102(d)(3)). Therefore, when establishing a BPA.... L. 111-5). (b) The contracting officer, when placing an order or establishing a BPA, is responsible... placed or the BPA is established. The requiring agency shall provide the information on the applicable...

Potential Application of Magnetohydrodynamic Acceleration to Hypersonic Environmental Testing

DTIC Science & Technology

1990-08-01

homopolar generators, and compulsators should be evaluated along with solid-state converters. 86 AEDC-TR-90-6 B.4.2 Design Study of Control and...heater as a source of hot air for accelerator research. One could consider using motor generator power supplies for the arc heater as d3ne tor the

49 CFR 538.9 - Dual fuel vehicle incentive.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 49 Transportation 6 2012-10-01 2012-10-01 false Dual fuel vehicle incentive. 538.9 Section 538.9... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION MANUFACTURING INCENTIVES FOR ALTERNATIVE FUEL VEHICLES § 538.9 Dual fuel vehicle incentive. The application of 49 U.S.C. 32905(b) and (d) to qualifying dual fuel vehicles...

76 FR 64816 - Deduction for Qualified Film and Television Production Costs

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-19

..., Deputy Commissioner for Services and Enforcement. Approved: September 19, 2011. Emily S. McMahon, Acting...(b) and (d) of the Administrative Procedure Act (5 U.S.C. chapter 5) does not apply to these regulations. For applicability of the Regulatory Flexibility Act (5 U.S.C. chapter 6), please refer to the...

76 FR 71276 - Common Crop Insurance Regulations; Pecan Revenue Crop Insurance Provisions

Federal Register 2010, 2011, 2012, 2013, 2014

2011-11-17

... CFR part 400, subpart J for the informal administrative review process of good farming practices as... farming operation. For instance, all producers are required to submit an application and acreage report to... and discourages good management practices. Language in sections 3(d)(3) and 6(b) provides consequences...

75 FR 22508 - Airworthiness Directives; Eurocopter France Model AS350B, BA, B1, B2, B3, C, D, and D1; AS 355E...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-29

... Airworthiness Directives; Eurocopter France Model AS350B, BA, B1, B2, B3, C, D, and D1; AS 355E, F, F1, F2, N... (b) None. Applicability (c) This AD applies to Model AS350B, BA, B1, B2, B3, C, D and D1; and AS 355E..., both dated November 16, 2005, is approved by the Director of the Federal Register as of May 14, 2010...

SU-E-J-174: Adaptive PET-Based Dose Painting with Tomotherapy

DOE Office of Scientific and Technical Information (OSTI.GOV)

Darwish, N; Mackie, T; Thomadsen, B

2014-06-01

Purpose: PET imaging can be converted into dose prescription directly. Due to the variability of the intensity of PET the image, PET prescription maybe superior over uniform dose prescription. Furthermore, unlike the case in image reconstruction of not knowing the image solution in advance, the prescribed dose is known from a PET image a priori. Therefore, optimum beam orientations are derivable. Methods: We can assume the PET image to be the prescribed dose and invert it to determine the energy fluence. The same method used to reconstruct tissue images from projections could be used to solve the inverse problem ofmore » determining beam orientations and modulation patterns from a dose prescription [10]. Unlike standard tomographic reconstruction of images from measured projection profiles, the inversion of the prescribed dose results in photon fluence which may be negative and therefore unphysical. Two-dimensional modulated beams can be modelled in terms of the attenuated or exponential radon transform of the prescribed dose function (assumed to be the PET image in this case), an application of a Ram-Lak filter, and inversion by backprojection. Unlike the case in PET processing, however, the filtered beam obtained from the inversion represents a physical photon fluence. Therefore, a positivity constraint for the fluence (setting negative fluence to zero) must be applied (Brahme et al 1982, Bortfeld et al 1990) Results: Truncating the negative profiles from the PET data results in an approximation of the derivable energy fluence. Backprojection of the deliverable fluence is an approximation of the dose delivered. The deliverable dose is comparable to the original PET image and is similar to the PET image. Conclusion: It is possible to use the PET data or image as a direct indicator of deliverable fluence for cylindrical radiotherapy systems such as TomoTherapy.« less

The influence of CYP2B6, CYP2C9 and CYP2D6 genotypes on the formation of the potent antioestrogen Z-4-hydroxy-tamoxifen in human liver.

PubMed

Coller, Janet K; Krebsfaenger, Niels; Klein, Kathrin; Endrizzi, Karin; Wolbold, Renzo; Lang, Thomas; Nüssler, Andreas; Neuhaus, Peter; Zanger, Ulrich M; Eichelbaum, Michel; Mürdter, Thomas E

2002-08-01

To investigate in a large panel of 50 human liver samples the contribution of CYP2C9, CYP2D6, and CYP3A4 to the overall formation of the potent antioestrogen Z-4-hydroxy-tamoxifen, and how various genotypes affect its formation from tamoxifen. The formation of Z-4-hydroxy-tamoxifen from 10 microm tamoxifen was studied in human liver microsomes (n=50), characterized for CYP2B6, CYP2C9, CYP2D6 and CYP3A4 expression, and CYP2B6, CYP2C9 and CYP2D6 genotype. The effect of chemical and monoclonal antibody inhibitors, and the formation in supersomes expressing recombinant CYP isoforms was also investigated. Z-4-hydroxy-tamoxifen was quantified using LC-MS analysis. Z-4-hydroxy-tamoxifen was formed by supersomes expressing CYP2B6, CYP2C9, CYP2C19 and CYP2D6, but not CYP3A4. In agreement with these data, the mean formation of Z-4-hydroxy-tamoxifen was inhibited 49% by sulphaphenazole (P=0.001), 38% by quinidine (P<0.05) and 13% by monoclonal antibody against CYP2B6 (MAB-2B6, P<0.05). Furthermore, Z-4-hydroxy-tamoxifen formation significantly correlated with both CYP2C9 expression (r(s)=0.256, P<0.05) and CYP2D6 expression (r(s)=0.309, P<0.05). Genotypes of CYP2D6, CYP2B6 and CYP2C9 had an effect on metabolite formation in such a way that samples with two nonfunctional CYP2D6, or two variant CYP2C9 or CYP2B6 alleles, showed lower enzyme activity compared with those with two functional or wild-type alleles, (5.0 vs 9.9 pmol mg(-1) protein min(-1), P=0.046, 5.1 vs 9.9 pmol mg(-1) protein min(-1), P=0.053, and 6.8 vs 9.4 pmol mg(-1) protein min(-1), P=0.054, respectively). CYP2D6 and CYP2C9 contribute on average 45 and 46%, respectively, to the overall formation of Z-4-hydroxy-tamoxifen. CYP2B6, CYP2C9 and CYP2D6 genotypes all affected Z-4-hydroxy-tamoxifen formation and can predict individual ability to catalyse this reaction.

Silica-Immobilized Enzyme Reactors; Application to Cholinesterase-Inhibition Studies

DTIC Science & Technology

2006-03-01

a i a i e v b c a m p l 1 d Journal of Chromatography B, 843 (2006) 310–316 Silica-immobilized enzyme reactors; application to...however, have specific omat d t t i w i h c u C p R n t o t fl p f o l p d v t o s fl t t c t a b f c i h a t s m i b 2 2 ≈ c s 0 c A R I H l 2 b p a y ε c...b r T p d ( m 2 w

Automated Neuropsychological Assessment Metrics, Version 4 (ANAM4): Examination of Select Psychometric Properties and Administration Procedures

DTIC Science & Technology

2016-12-01

2017 was approved in August 2016. The supplemental project has 2 primary objectives: • Recommend cognitive assessment tools/approaches ( toolkit ) from...strategies for use in future military-relevant environments The supplemental project has two primary deliverables: • Proposed Toolkit of cognitive...6 Vet Final Report and Cognitive performance recommendations through Steering Committee Task 7 Provide Toolkit Report 16 Months 8-12 Task 8

High-Frequency Spin-Based Devices for Nanoscale Signal Processing

DTIC Science & Technology

2009-01-20

feedback on the devices in order to improve their spectral properties . Deliverable: Microwave signals without an Applied Field. We have successfully...additionally have the advantage of higher operating frequencies than the more conventional devices based on NiFe alloys. By combining several of...Output from a Co/Ni based STNO. Corresponds to approximately 20 nW, about 10 times larger than typical NiFe .device. 6 High-Frequency Spin-Based

Inheritance of steroid-independent male sexual behavior in male offspring of B6D2F1 mice.

PubMed

McInnis, Christine M; Bonthuis, Paul J; Rissman, Emilie F; Park, Jin Ho

2016-04-01

The importance of gonadal steroids in modulating male sexual behavior is well established. Individual differences in male sexual behavior, independent of gonadal steroids, are prevalent across a wide range of species, including man. However, the genetic mechanisms underlying steroid-independent male sexual behavior are poorly understood. A high proportion of B6D2F1 hybrid male mice demonstrates steroid-independent male sexual behavior (identified as "maters"), providing a mouse model that opens up avenues of investigation into the mechanisms regulating male sexual behavior in the absence of gonadal hormones. Recent studies have revealed several proteins that play a significant factor in regulating steroid-independent male sexual behavior in B6D2F1 male mice, including amyloid precursor protein (APP), tau, and synaptophysin. The specific goals of our study were to determine whether steroid-independent male sexual behavior was a heritable trait by determining if it was dependent upon the behavioral phenotype of the B6D2F1 sire, and whether the differential expression of APP, tau, and synaptophysin in the medial preoptic area found in the B6D2F1 sires that did and did not mate after gonadectomy was similar to those found in their male offspring. After adult B6D2F1 male mice were bred with C57BL/6J female mice, they and their male offspring (BXB1) were orchidectomized and identified as either maters or "non-maters". A significant proportion of the BXB1 maters was sired only from B6D2F1 maters, indicating that the steroid-independent male sexual behavior behavioral phenotype of the B6D2F1 hybrid males, when crossed with C57BL/6J female mice, is inherited by their male offspring. Additionally, APP, tau, and synaptophysin were elevated in in the medial preoptic area in both the B6D2F1 and BXB1 maters relative to the B6D2F1 and BXB1 non-maters, respectively, suggesting a potential genetic mechanism for the inheritance of steroid-independent male sexual behavior. Copyright © 2016 Elsevier Inc. All rights reserved.

Inheritance of steroid-independent male sexual behavior in male offspring of B6D2F1 mice

PubMed Central

McInnis, Christine M.; Bonthuis, Paul J.; Rissman, Emilie F.; Park, Jin Ho

2016-01-01

The importance of gonadal steroids in modulating male sexual behavior is well established. Individual differences in male sexual behavior, independent of gonadal steroids, are prevalent across a wide range of species, including man. However, the genetic mechanisms underlying steroid-independent male sexual behavior are poorly understood. A high proportion of B6D2F1 hybrid male mice demonstrate steroid-independent male sexual behavior (identified as “maters”), providing a mouse model that opens up avenues of investigation into the mechanisms regulating male sexual behavior in the absence of gonadal hormones. Recent studies have revealed several proteins that play a significant factor in regulating steroid-independent male sexual behavior in B6D2F1 male mice, including amyloid precursor protein (APP), tau, and synaptophysin. The specific goals of our study were to determine whether steroid-independent male sexual behavior was a heritable trait by determining if it was dependent upon the behavioral phenotype of the B6D2F1 sire, and whether the differential expression of APP, tau, and synaptophysin in the medial preoptic area found in the B6D2F1 sires that did and did not mate after gonadectomy was similar to those found in their male offspring. After adult B6D2F1 male mice were bred with C57BL/6J female mice, they and their male offspring (BXB1) were orchidectomized and identified as either maters or “non-maters.” A significant proportion of the BXB1 maters were sired only from B6D2F1 maters, indicating that the steroid-independent male sexual behavior behavioral phenotype of the B6D2F1 hybrid males, when crossed with C57BL/6J female mice, is inherited by their male offspring. Additionally, APP, tau, and synaptophysin were elevated in in the medial preoptic area in both the B6D2F1 and BXB1 maters relative to the B6D2F1 and BXB1 non-maters, respectively, suggesting a potential genetic mechanism for the inheritance of steroid-independent male sexual behavior. PMID:26940434

Flexible microstrip antenna based on carbon nanotubes/(ethylene-octene copolymer) thin composite layer deposited on PET substrate

NASA Astrophysics Data System (ADS)

Matyas, J.; Olejnik, R.; Slobodian, P.

2017-12-01

A most of portable devices, such as mobile phones, tablets, uses antennas made of cupper. In this paper we demonstrate possible use of electrically conductive polymer composite material for such antenna application. Here we describe the method of preparation and properties of the carbon nanotubes (CNTs)/(ethylene-octene copolymer) as flexible microstrip antenna. Carbon nanotubes dispersion in (ethylene-octene copolymer) toluene solution was prepared by ultrasound finally coating PET substrate by method of dip-coating. Main advantages of PET substrate are low weight and also flexibility. The final size of flexible microstrip antenna was 5 x 50 mm with thickness of 0.48 mm (PET substrate 0.25 mm) with the weight of only 0.402 g. Antenna operates at three frequencies 1.66 GHz (-6.51 dB), 2.3 GHz (-13 dB) and 2.98 GHz (-33.59 dB).

Optimum concentric circular array antenna with high gain and side lobe reduction at 5.8 GHz

NASA Astrophysics Data System (ADS)

Zaid, Mohammed; Rafiqul Islam, Md; Habaebi, Mohamed H.; Zahirul Alam, AHM; Abdullah, Khaizuran

2017-11-01

The significance of high gain directional antennas stems from the need to cope up with the everyday progressing wireless communication systems. Due to low gain of the widely used microstrip antenna, combining multiple antennas in proper geometry increases the gain with good directive property. Over other array forms, this paper uses concentric circular array configuration for its compact structure and inherent symmetry in azimuth. This proposed array is composed of 9 elements on FR-4 substrate, which is designed for WLAN applications at 5.8GHz. Antenna Magus software is used for synthesis, while CST software is used for optimization. The proposed array is designed with optimum inter-element spacing and number of elements achieving a high directional gain of 15.7 dB compared to 14.2 dB of available literature, with a high reduction in side lobe level of -17.6 dB.

Access Point Selection for Multi-Rate IEEE 802.11 Wireless LANs

DTIC Science & Technology

2014-05-16

Mobile Systems, Applications and Services, 2006. [2] S . Vasudevan, K. Papagiannaki, C . Diot, J. Kurose, and D. Towsley, “Facilitating Access Point...LANs 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR( S ) 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7...PERFORMING ORGANIZATION NAME( S ) AND ADDRESS(ES) University of California at Berkeley,Electrical Engineering and Computer Sciences,Berkeley,CA,94720 8

Proceedings of the Antenna Applications Symposium (1988) Volume 1

DTIC Science & Technology

1989-06-01

FIELD GROUP SUB-GROUP Antennas)p Microstrip, ,.Multibeam Antennas 6 Satellite Antennas. Reflector Array Antennas, ____________I____ Broadband Antennas...C. Sullivan and G. E. Evans 8. " Broadband MMIC T/R Module/Subarray Performance," D. Brubaker, 157 D. Scott, S. Ludvik, M. Lynch, H. II. Chung, W...34 S. Sanzgiri, 277 B. Powers, Jr., and J. Hart ib. " broadbanding Techniques for Microstrip Patch Antennas - A ’.93 kReview," K. C. Gupta * NUT INCLUDED

The Use of D-Optimal Mixture Design in Optimising Okara Soap Formulation for Stratum Corneum Application

PubMed Central

Borhan, Farrah Payyadhah; Abd Gani, Siti Salwa; Shamsuddin, Rosnah

2014-01-01

Okara, soybean waste from tofu and soymilk production, was utilised as a natural antioxidant in soap formulation for stratum corneum application. D-optimal mixture design was employed to investigate the influence of the main compositions of okara soap containing different fatty acid and oils (virgin coconut oil A (24–28% w/w), olive oil B (15–20% w/w), palm oil C (6–10% w/w), castor oil D (15–20% w/w), cocoa butter E (6–10% w/w), and okara F (2–7% w/w)) by saponification process on the response hardness of the soap. The experimental data were utilized to carry out analysis of variance (ANOVA) and to develop a polynomial regression model for okara soap hardness in terms of the six design factors considered in this study. Results revealed that the best mixture was the formulation that included 26.537% A, 19.999% B, 9.998% C, 16.241% D, 7.633% E, and 7.000% F. The results proved that the difference in the level of fatty acid and oils in the formulation significantly affects the hardness of soap. Depending on the desirable level of those six variables, creation of okara based soap with desirable properties better than those of commercial ones is possible. PMID:25548777

Novel mode of inhibition by D-tagatose 6-phosphate through a Heyns rearrangement in the active site of transaldolase B variants.

PubMed

Stellmacher, Lena; Sandalova, Tatyana; Schneider, Sarah; Schneider, Gunter; Sprenger, Georg A; Samland, Anne K

2016-04-01

Transaldolase B (TalB) and D-fructose-6-phosphate aldolase A (FSAA) from Escherichia coli are C-C bond-forming enzymes. Using kinetic inhibition studies and mass spectrometry, it is shown that enzyme variants of FSAA and TalB that exhibit D-fructose-6-phosphate aldolase activity are inhibited covalently and irreversibly by D-tagatose 6-phosphate (D-T6P), whereas no inhibition was observed for wild-type transaldolase B from E. coli. The crystal structure of the variant TalB(F178Y) with bound sugar phosphate was solved to a resolution of 1.46 Å and revealed a novel mode of covalent inhibition. The sugar is bound covalently via its C2 atom to the ℇ-NH2 group of the active-site residue Lys132. It is neither bound in the open-chain form nor as the closed-ring form of D-T6P, but has been converted to β-D-galactofuranose 6-phosphate (D-G6P), a five-membered ring structure. The furanose ring of the covalent adduct is formed via a Heyns rearrangement and subsequent hemiacetal formation. This reaction is facilitated by Tyr178, which is proposed to act as acid-base catalyst. The crystal structure of the inhibitor complex is compared with the structure of the Schiff-base intermediate of TalB(E96Q) formed with the substrate D-fructose 6-phosphate determined to a resolution of 2.20 Å. This comparison highlights the differences in stereochemistry at the C4 atom of the ligand as an essential determinant for the formation of the inhibitor adduct in the active site of the enzyme.

DOE Office of Scientific and Technical Information (OSTI.GOV)

None, None

The multi-agent system (MAS) approach has been applied with promising results for enhancing an electric power distribution circuit, such as the Circuit of the Future as developed by Southern California Edison. These next generation power system results include better ability to reconfigure the circuit as well as the increased capability to improve the protection and enhance the reliability of the circuit. There were four main tasks in this project. The specific results for each of these four tasks and their related topics are presented in main sections of this report. Also, there were seven deliverables for this project. The mainmore » conclusions for these deliverables are summarized in the identified subtask section of this report. The specific details for each of these deliverables are included in the “Project Deliverables” section at the end of this Final Report.« less

Life Prediction of Fretting Fatigue with Advanced Surface Treatments (Preprint)

DTIC Science & Technology

2006-05-01

surfaces and not the fretting pads. The chosen coatings included DLC, Ni-B, Molybdenum, and Nitride. These 4 coatings, their application to the titanium ...Article Preprint 5a. CONTRACT NUMBER In-house 5b. GRANT NUMBER 4 . TITLE AND SUBTITLE LIFE PREDICTION OF FRETTING FATIGUE WITH ADVANCED SURFACE...TREATMENTS (PREPRINT) 5c. PROGRAM ELEMENT NUMBER N/A 5d. PROJECT NUMBER M02R 5e. TASK NUMBER 30 6 . AUTHOR(S) Patrick J. Golden and Michael

Fire Performance of Shipboard Electronic Space Materials

DTIC Science & Technology

2006-09-15

5d. PROJECT NUMBER 61-8513-0-6-5 John B. Hoover, Clarence L. Whitehurst, Eric B. Chang, and Frederick W. Williams 5e . TASK NUMBER 5f. WORK UNIT NUMBER...representative of current US Navy surface ship electronic spaces. It is expected that lessons learned from tests of this configuration will be applicable... NGSS ) for use on current construction DDG-51 class destroyers. The panels consist of a Nomex honeycomb core with a GRP (glass reinforced plastic

3D animation in three dimensions: the rocky road to the obvious

NASA Astrophysics Data System (ADS)

Murray, Hugh

2006-02-01

That animation created using CG modeling and animation tools is inherently three-dimensional is well known. In the middle to late nineties IMAX Corporation began actively exploring CG animated features as a possible source of economically viable content for its rapidly growing network of stereoscopic IMAX® 3D theatres. The journey from there to the spectacular success of the IMAX® 3D version of The Polar Express is an interesting mix of technical, creative and production challenges. For example 3D animations often have 2D elements and include many sequences that have framing, composition and lens choices that a stereographer would have avoided had 3D been part of the recipe at the outset. And of course the decision to ask for a second set of deliverables from an already stressed production takes nerve. The talk will cover several of these issues and explain why the unique viewing experience enabled by the wideangle geometry of IMAX® 3D theatres makes it worth all the pain.

Inhibition of tumor angiogenesis and tumor growth by the DSL domain of human Delta-like 1 targeted to vascular endothelial cells.

PubMed

Zhao, Xing-Cheng; Dou, Guo-Rui; Wang, Li; Liang, Liang; Tian, Deng-Mei; Cao, Xiu-Li; Qin, Hong-Yan; Wang, Chun-Mei; Zhang, Ping; Han, Hua

2013-07-01

The growth of solid tumors depends on neovascularization. Several therapies targeting tumor angiogenesis have been developed. However, poor response in some tumors and emerging resistance necessitate further investigations of new drug targets. Notch signal pathway plays a pivotal role in vascular development and tumor angiogenesis. Either blockade or forced activation of this pathway can inhibit angiogenesis. As blocking Notch pathway results in the formation of vascular neoplasm, activation of Notch pathway to prevent tumor angiogenesis might be an alternative choice. However, an in vivo deliverable reagent with highly efficient Notch-activating capacity has not been developed. Here, we generated a polypeptide, hD1R, which consists of the Delta-Serrate-Lag-2 fragment of the human Notch ligand Delta-like 1 and an arginine-glycine-aspartate (RGD) motif targeting endothelial cells (ECs). We showed that hD1R could bind to ECs specifically through its RGD motif and effectively triggered Notch signaling in ECs. We demonstrated both in vitro and in vivo that hD1R inhibited angiogenic sprouting and EC proliferation. In tumor-bearing mice, the injection of hD1R effectively repressed tumor growth, most likely through increasing tumor hypoxia and tissue necrosis. The amount and width of vessels reduced remarkably in tumors of mice treated with hD1R. Moreover, vessels in tumors of mice treated with hD1R recruited more NG2(+) perivascular cells and were better perfused. Combined application of hD1R and chemotherapy with cisplatin and teniposide revealed that these two treatments had additive antitumor effects. Our study provided a new strategy for antiangiogenic tumor therapy.

Investigation of AWG demultiplexer based SOI for CWDM application

NASA Astrophysics Data System (ADS)

Juhari, Nurjuliana; Susthitha Menon, P.; Shaari, Sahbudin; Annuar Ehsan, Abang

2017-11-01

9-channel Arrayed Waveguide Grating (AWG) demultiplexer for conventional and tapered structure were simulated using beam propagation method (BPM) with channel spacing of 20 nm. The AWG demultiplexer was design using high refractive index (n 3.47) material namely silicon-on-insulator (SOI) with rib waveguide structure. The characteristics of insertion loss, adjacent crosstalk and output spectrum response at central wavelength of 1.55 μm for both designs were compared and analyzed. The conventional AWG produced a minimum insertion loss of 6.64 dB whereas the tapered AWG design reduced the insertion loss by 2.66 dB. The lowest adjacent crosstalk value of -16.96 dB was obtained in the conventional AWG design and this was much smaller compared to the tapered AWG design where the lowest crosstalk value is -17.23 dB. Hence, a tapered AWG design significantly reduces the insertion loss but has a slightly higher adjacent crosstalk compared to the conventional AWG design. On the other hand, the output spectrum responses that are obtained from both designs were close to the Coarse Wavelength Division Multiplexing (CWDM) wavelength grid.

Optical back propagation for fiber optic networks with hybrid EDFA Raman amplification.

PubMed

Liang, Xiaojun; Kumar, Shiva

2017-03-06

We have investigated an optical back propagation (OBP) method to compensate for propagation impairments in fiber optic networks with lumped Erbium doped fiber amplifier (EDFA) and/or distributed Raman amplification. An OBP module consists of an optical phase conjugator (OPC), optical amplifiers and dispersion varying fibers (DVFs). We derived a semi-analytical expression that calculates the dispersion profile of DVF. The OBP module acts as a nonlinear filter that fully compensates for the nonlinear distortions due to signal propagation in a transmission fiber, and is applicable for fiber optic networks with reconfigurable optical add-drop multiplexers (ROADMs). We studied a wavelength division multiplexing (WDM) network with 3000 km transmission distance and 64-quadrature amplitude modulation (QAM) modulation. OBP brings 5.8 dB, 5.9 dB and 6.1 dB Q-factor gains over linear compensation for systems with full EDFA amplification, hybrid EDFA/Raman amplification, and full Raman amplification, respectively. In contrast, digital back propagation (DBP) or OPC-only systems provide only 0.8 ~ 1.5 dB Q-factor gains.

Channel Modeling of Miniaturized Battery-Powered Capacitive Human Body Communication Systems.

PubMed

Park, Jiwoong; Garudadri, Harinath; Mercier, Patrick P

2017-02-01

The purpose of this contribution is to estimate the path loss of capacitive human body communication (HBC) systems under practical conditions. Most prior work utilizes large grounded instruments to perform path loss measurements, resulting in overly optimistic path loss estimates for wearable HBC devices. In this paper, small battery-powered transmitter and receiver devices are implemented to measure path loss under realistic assumptions. A hybrid electrostatic finite element method simulation model is presented that validates measurements and enables rapid and accurate characterization of future capacitive HBC systems. Measurements from form-factor-accurate prototypes reveal path loss results between 31.7 and 42.2 dB from 20 to 150 MHz. Simulation results matched measurements within 2.5 dB. Comeasurements using large grounded benchtop vector network analyzer (VNA) and large battery-powered spectrum analyzer (SA) underestimate path loss by up to 33.6 and 8.2 dB, respectively. Measurements utilizing a VNA with baluns, or large battery-powered SAs with baluns still underestimate path loss by up to 24.3 and 6.7 dB, respectively. Measurements of path loss in capacitive HBC systems strongly depend on instrumentation configurations. It is thus imperative to simulate or measure path loss in capacitive HBC systems utilizing realistic geometries and grounding configurations. HBC has a great potential for many emerging wearable devices and applications; accurate path loss estimation will improve system-level design leading to viable products.

15 CFR 742.10 - Anti-terrorism: Sudan.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 2 and 3 chemicals controlled under ECCN 1E355. (xi) Ammonium nitrate, including certain fertilizers containing ammonium nitrate, controlled under ECCN 1C997. (2) Applications for the export and reexport of all... 2A994; 3A992.a; 5A991.g; 5A992; 6A991; 6A998; 7A994; 8A992.d, .e, .f, and .g; 9A990.a and .b; and 9A991...

Analgesia and Opioids: A Pharmacogenetics Shortlist for Implementation in Clinical Practice.

PubMed

Matic, Maja; de Wildt, Saskia N; Tibboel, Dick; van Schaik, Ron H N

2017-07-01

The use of opioids to alleviate pain is complicated by the risk of severe adverse events and the large variability in dose requirements. Pharmacogenetics (PGx) could possibly be used to tailor pain medication based on an individual's genetic background. Many potential genetic markers have been described, and the importance of genetic predisposition in opioid efficacy and toxicity has been demonstrated in knockout mouse models and human twin studies. Such predictors are especially of value for neonates and young children, in whom the assessment of efficacy or side effects is complicated by the inability of the patient to communicate this properly. The current problem is determining which of the many potential candidates to focus on for clinical implementation. We systematically searched publications on PGx for opioids in 5 databases, aiming to identify PGx markers with sufficient robust data and high enough occurrence for potential clinical application. The initial search yielded 4257 unique citations, eventually resulting in 852 relevant articles covering 24 genes. From these genes, we evaluated the evidence and selected the most promising 10 markers: cytochrome P450 family 2 subfamily D member 6 ( CYP2D6 ), cytochrome P450 family 3 subfamily A member 4 ( CYP3A4 ), cytochrome P450 family 3 subfamily A member 5 ( CYP3A5 ), UDP glucuronosyltransferase family 2 member B7 ( UGT2B7 ), ATP binding cassette subfamily B member 1 ( ABCB1 ), ATP binding cassette subfamily C member 3 ( ABCC3 ), solute carrier family 22 member 1 ( SLC22A1 ), opioid receptor kappa 1 ( OPRM1 ), catechol- O -methyltransferase ( COMT ), and potassium voltage-gated channel subfamily J member 6 ( KCNJ6 ). Treatment guidelines based on genotype are already available only for CYP2D6 . The application of PGx in the management of pain with opioids has the potential to improve therapy. We provide a shortlist of 10 genes that are the most promising markers for clinical use in this context. © 2016 American Association for Clinical Chemistry.

The Crystal Structure and Magnetic Behavior of Quinary Osmate and Ruthenate Double Perovskites La ABB'O 6 ( A = Ca, Sr; B = Co, Ni; B' = Ru, Os)

DOE PAGES

Morrow, Ryan; McGuire, Michael A.; Yan, Jiaqiang; ...

2018-02-23

In this work, six LaABB'O 6 (A = Ca, Sr; B = Co, Ni; B' = Ru, Os) double perovskites were synthesized, several for the first time, and their crystal structures and magnetic behavior were characterized with neutron powder diffraction and direct-current and alternating-current magnetometry. All six compounds crystallize with P2 1/n space group symmetry, resulting from a –a –c + octahedral tilting and complete rock salt ordering of transition-metal ions. Despite the electronic configurations of the transition-metal ions, either d 8–d 3 or d 7–d 3, not one of the six compounds shows ferromagnetism as predicted by the Goodenough–Kanamorimore » rules. LaSrNiOsO 6, LaSrNiRuO 6, and LaCaNiRuO 6 display long-range antiferromagnetic order, while LaCaNiOsO 6, LaCaCoOsO 6, and LaSrCoOsO 6 exhibit spin-glass behavior. These compounds are compared to the previously studied LaCaCoRuO 6 and LaSrCoRuO 6, both of which order antiferromagnetically. Lastly, the observed variations in magnetic properties can be attributed largely to the response of competing superexchange pathways due to changes in B–O–B' bond angles, differences in the radial extent of the 4d (B' = Ru) and 5d (B' = Os) orbitals, and filling of the t 2g orbitals of the 3d ion.« less

The Crystal Structure and Magnetic Behavior of Quinary Osmate and Ruthenate Double Perovskites La ABB'O 6 ( A = Ca, Sr; B = Co, Ni; B' = Ru, Os)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Morrow, Ryan; McGuire, Michael A.; Yan, Jiaqiang

In this work, six LaABB'O 6 (A = Ca, Sr; B = Co, Ni; B' = Ru, Os) double perovskites were synthesized, several for the first time, and their crystal structures and magnetic behavior were characterized with neutron powder diffraction and direct-current and alternating-current magnetometry. All six compounds crystallize with P2 1/n space group symmetry, resulting from a –a –c + octahedral tilting and complete rock salt ordering of transition-metal ions. Despite the electronic configurations of the transition-metal ions, either d 8–d 3 or d 7–d 3, not one of the six compounds shows ferromagnetism as predicted by the Goodenough–Kanamorimore » rules. LaSrNiOsO 6, LaSrNiRuO 6, and LaCaNiRuO 6 display long-range antiferromagnetic order, while LaCaNiOsO 6, LaCaCoOsO 6, and LaSrCoOsO 6 exhibit spin-glass behavior. These compounds are compared to the previously studied LaCaCoRuO 6 and LaSrCoRuO 6, both of which order antiferromagnetically. Lastly, the observed variations in magnetic properties can be attributed largely to the response of competing superexchange pathways due to changes in B–O–B' bond angles, differences in the radial extent of the 4d (B' = Ru) and 5d (B' = Os) orbitals, and filling of the t 2g orbitals of the 3d ion.« less

High-performance and high-reliability SOT-6 packaged diplexer based on advanced IPD fabrication techniques

NASA Astrophysics Data System (ADS)

Qiang, Tian; Wang, Cong; Kim, Nam-Young

2017-08-01

A diplexer offering the advantages of compact size, high performance, and high reliability is proposed on the basis of advanced integrated passive device (IPD) fabrication techniques. The proposed diplexer is developed by combining a third-order low-pass filter (LPF) and a third-order high-pass filter (HPF), which are designed on the basis of the elliptic function prototype low-pass filter. Primary components, such as inductors and capacitors, are designed and fabricated with high Q-factor and appropriate values, and they are subsequently used to construct a compact diplexer having a chip area of 900 μm × 1100 μm (0.009 λ0 × 0.011 λ0, where λ0 is the guided wavelength). In addition, a small-outline transistor (SOT-6) packaging method is adopted, and reliability tests (including temperature, humidity, vibration, and pressure) are conducted to guarantee long-term stability and commercial success. The packaged measurement results indicate excellent RF performance with insertion losses of 1.39 dB and 0.75 dB at operation bands of 0.9 GHz and 1.8 GHz, respectively. The return loss is lower than 10 dB from 0.5 GHz to 4.0 GHz, while the isolation is higher than 15 dB from 0.5 GHz to 3.0 GHz. Thus, it can be concluded that the proposed SOT-6 packaged diplexer is a promising candidate for GSM/CDMA applications. Synthetic solution of diplexer design, RF performance optimization, fabrication process, packaging, RF response measurement, and reliability test is particularly explained and analyzed in this work.

Managing with A/E Ease

DTIC Science & Technology

1988-07-01

16. Construction Fixes ($K). ([ a16(s) [ bl6 (s)] [ d16(s) 17. Final Actions on Pursuit Cases. ([ a17(s) ]) [bl7(s)] [ d17(s) 18. Carry Over to Next...Construction Fixes ($K). ( [al6 ]) [ b16 ] [d16 17. Final Actions on Pursuit Cases. ( [a17 ]) [b17 ] [d17 18. Carry Over to Next Quarter. [b18 ] [d18 .else

Shear horizontal surface acoustic wave microsensor for Class A viral and bacterial detection.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Branch, Darren W.; Huber, Dale L.; Brozik, Susan Marie

The rapid autonomous detection of pathogenic microorganisms and bioagents by field deployable platforms is critical to human health and safety. To achieve a high level of sensitivity for fluidic detection applications, we have developed a 330 MHz Love wave acoustic biosensor on 36{sup o} YX Lithium Tantalate (LTO). Each die has four delay-line detection channels, permitting simultaneous measurement of multiple analytes or for parallel detection of single analyte containing samples. Crucial to our biosensor was the development of a transducer that excites the shear horizontal (SH) mode, through optimization of the transducer, minimizing propagation losses and reducing undesirable modes. Detectionmore » was achieved by comparing the reference phase of an input signal to the phase shift from the biosensor using an integrated electronic multi-readout system connected to a laptop computer or PDA. The Love wave acoustic arrays were centered at 330 MHz, shifting to 325-328 MHz after application of the silicon dioxide waveguides. The insertion loss was -6 dB with an out-of-band rejection of 35 dB. The amplitude and phase ripple were 2.5 dB p-p and 2-3{sup o} p-p, respectively. Time-domain gating confirmed propagation of the SH mode while showing suppression of the triple transit. Antigen capture and mass detection experiments demonstrate a sensitivity of 7.19 {+-} 0.74{sup o} mm{sup 2}/ng with a detection limit of 6.7 {+-} 0.40 pg/mm{sup 2} for each channel.« less

78 FR 7835 - Self-Regulatory Organizations; BOX Options Exchange LLC; Notice of Filing of Proposed Rule Change...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-04

... at $145 per share would carry a total deliverable value of $145,000, and the strike price would be... Jumbo option strike price of $145 was trading at $146 per share, the intrinsic $1 per share value would... Shares Deliverable Upon Exercise 100 shares........ 1,000 shares Strike Price if underlying is 45 45 $45...

Summary of FY 17 Assessments Sandia National Laboratories: Evaluation of FY16 SNL FCT M2 Milestone Deliverables

DOE Office of Scientific and Technical Information (OSTI.GOV)

Appel, Gordon John

This report is the milestone deliverable M4FT-17SN111102091 “Summary of Assessments Performed FY17 by SNL QA POC” for work package FT-17SN11110209 titled “Quality Assurance – SNL”. This report summarizes the FY17 assessment performed on Fuel Cycle Technologies / Spent Fuel and Waste Disposition efforts.

Medical and Non-Medical Predictors of Disability Discharge Disposition for Navy Personnel with a Back Problem: A Focus on Entitlement

DTIC Science & Technology

1988-03-28

Washington D.C. 20350-1000. Stryker, S., & Gottlieb, A. (1981). Attribution theory and symbolic interactionism : A comparison. In J.H. Howes, W...ERFORMIING ORGANIZATION 6b OFFiCE SYMBOL 7a NAME OF MONITORING ORGANIZATION (If applicable) Naval Health Research Center 40 Commander, Naval Medical Command...Washington, DC 20372 ea NAME OF FUNDING/SPONSORING Bb OFFICE SYMBOL 9. PROCUREMENT INSTRUMENT IDENTIFICATION NUMBER ORGANIZATION Naval Medical (If applicable

DAPHNE silicon photonics technological platform for research and development on WDM applications

NASA Astrophysics Data System (ADS)

Baudot, Charles; Fincato, Antonio; Fowler, Daivid; Perez-Galacho, Diego; Souhaité, Aurélie; Messaoudène, Sonia; Blanc, Romuald; Richard, Claire; Planchot, Jonathan; De-Buttet, Come; Orlando, Bastien; Gays, Fabien; Mezzomo, Cécilia; Bernard, Emilie; Marris-Morini, Delphine; Vivien, Laurent; Kopp, Christophe; Boeuf, Frédéric

2016-05-01

A new technological platform aimed at making prototypes and feasibility studies has been setup at STMicroelectronics using 300mm wafer foundry facilities. The technology, called DAPHNE (Datacom Advanced PHotonic Nanoscale Environment), is devoted at developing and evaluating new devices and sub-systems in particular for wavelength division multiplexing (WDM) applications and ring resonator based applications. Developed in the course of PLAT4MFP7 European project, DAPHNE is a flexible platform that fits perfectly R&D needs. The fabrication flow enables the processing of photonic integrated circuits using a silicon-on-insulator (SOI) of 300nm, partial etches of 150nm and 50nm and a total silicon etching. Consequently, two varieties of rib waveguides and one strip waveguide can be fabricated simultaneously with auto-alignment properties. The process variability on the 150nm partially etched silicon and the thin 50nm slab region are both less than 6 nm. Using a variety of different implantation configurations and a back-end of line of 5 metal layers, active devices are fabricated both in germanium and silicon. An available far back-end of line process consists of making 20 μm diameter copper posts on top of the electrical pads so that an electronic integrated circuit can be bonded on top the photonic die by 3D integration. Besides having those fabrication process options, DAPHNE is equipped with a library of standard cells for optical routing and multiplexing. Moreover, typical Mach-Zehnder modulators based on silicon pn junctions are also available for optical signal modulation. To achieve signal detection, germanium photodetectors also exist as standard cells. The measured single-mode propagation losses are 3.5 dB/cm for strip, 3.7 dB/cm for deep-rib (50nm slab) and 1.4 dB/cm for standard rib (150nm slab) waveguides. Transition tapers between different waveguide structures are as low as 0.006 dB.

Search for B decays to final states with the η c meson

DOE PAGES

Vinokurova, A.; Kuzmin, A.; Eidelman, S.; ...

2015-06-18

We report a search for B decays to selected final states with the η c meson: B ± → K ±η cπ +π -, B ± → K ±η cω, B ± → K ±η cη and B ± → K ±η cπ 0. The analysis is based on 772 × 10 6 BB-bar pairs collected at the Υ(4S) resonance with the Belle detector at the KEKB asymmetric-energy e +e - collider. We set 90% confidence level upper limits on the branching fractions of the studied B decay modes, independent of intermediate resonances, in the range (0.6–5.3) × 10 -4.more » We also search for molecular-state candidates in the D 0D*-bar 0 - D-bar 0D* 0, D 0D-bar 0 + D-bar 0D 0 and D* 0D*-bar 0 + D*-bar 0D* 0 combinations, neutral partners of the Z(3900) ± and Z(4020) ±, and a poorly understood state X(3915) as possible intermediate states in the decay chain, and set 90% confidence level upper limits on the product of branching fractions to the mentioned intermediate states and decay branching fractions of these states in the range (0.6–6.9) × 10 -5.« less

21 CFR 74.2306 - D&C Red No. 6.

Code of Federal Regulations, 2010 CFR

2010-04-01

... ADDITIVES SUBJECT TO CERTIFICATION Cosmetics § 74.2306 D&C Red No. 6. (a) Identity and specifications.The color additive D&C Red No. 6 shall conform in identity and specifications to the requirements of § 74.1306 (a)(1) and (b). (b) Uses and restrictions. The color additive D&C Red No. 6 may be safely used for...

21 CFR 74.2306 - D&C Red No. 6.

Code of Federal Regulations, 2014 CFR

2014-04-01

... ADDITIVES SUBJECT TO CERTIFICATION Cosmetics § 74.2306 D&C Red No. 6. (a) Identity and specifications.The color additive D&C Red No. 6 shall conform in identity and specifications to the requirements of § 74.1306 (a)(1) and (b). (b) Uses and restrictions. The color additive D&C Red No. 6 may be safely used for...

21 CFR 74.2306 - D&C Red No. 6.

Code of Federal Regulations, 2013 CFR

2013-04-01

... ADDITIVES SUBJECT TO CERTIFICATION Cosmetics § 74.2306 D&C Red No. 6. (a) Identity and specifications.The color additive D&C Red No. 6 shall conform in identity and specifications to the requirements of § 74.1306 (a)(1) and (b). (b) Uses and restrictions. The color additive D&C Red No. 6 may be safely used for...

21 CFR 74.2306 - D&C Red No. 6.

Code of Federal Regulations, 2012 CFR

2012-04-01

... ADDITIVES SUBJECT TO CERTIFICATION Cosmetics § 74.2306 D&C Red No. 6. (a) Identity and specifications.The color additive D&C Red No. 6 shall conform in identity and specifications to the requirements of § 74.1306 (a)(1) and (b). (b) Uses and restrictions. The color additive D&C Red No. 6 may be safely used for...

Low dietary boron reduces parasite (nematoda) survival and alters cytokine profiles but the infection modifies liver minerals in mice.

PubMed

Bourgeois, Annie-Claude; Scott, Marilyn E; Sabally, Kebba; Koski, Kristine G

2007-09-01

Although boron (B) is an essential trace mineral, any interactions that it may have with gastrointestinal (GI) nematode infections are unknown. This study explored whether low dietary B would: 1) alter survival or reproduction of Heligmosomoides bakeri (Nematoda); 2) modify the resulting cytokine response to this parasitic infection; or 3) influence liver mineral concentrations in the infected host. Balb/c mice were fed either a low-B (0.2 microg B/g), marginal (2.0 microg B/g), or control (12.0 microg B/g) diet. Diets commenced 3 wk before a primary infection and were fed for 4 wk (primary infection protocol) and 8-9 wk (challenge infection protocol). Mice were killed 6 d post-primary infection (d6ppi), or dewormed then reinfected (challenge infection protocol) and killed 14 or 21 d post-challenge infection (d14pci or d21pci, respectively). Low and marginal dietary B intakes impaired survival of the parasite, reduced intestinal inflammation, and modulated a broad range of cytokines and chemokines despite similar liver B concentrations in diet groups. Compared with control mice, cytokine production was lower following low and marginal B intakes at d6ppi but was elevated at d21pci. Serum alkaline phosphatase was higher at d6ppi than at d14pci and d21pci. Compared with d14pci, liver zinc, iron, and B concentrations were reduced at d21pci when worm numbers were also lower, whereas concentrations of sodium, potassium, molybdenum, chromium, and sulfur were higher. This study shows that parasite survival and cytokine and inflammatory responses are modified by dietary B intake but indicates that a GI nematode infection alters liver mineral concentrations.

A Wideband Circularly Polarized Pixelated Dielectric Resonator Antenna.

PubMed

Trinh-Van, Son; Yang, Youngoo; Lee, Kang-Yoon; Hwang, Keum Cheol

2016-08-23

The design of a wideband circularly polarized pixelated dielectric resonator antenna using a real-coded genetic algorithm (GA) is presented for far-field wireless power transfer applications. The antenna consists of a dielectric resonator (DR) which is discretized into 8 × 8 grid DR bars. The real-coded GA is utilized to estimate the optimal heights of the 64 DR bars to realize circular polarization. The proposed antenna is excited by a narrow rectangular slot etched on the ground plane. A prototype of the proposed antenna is fabricated and tested. The measured -10 dB reflection and 3 dB axial ratio bandwidths are 32.32% (2.62-3.63 GHz) and 14.63% (2.85-3.30 GHz), respectively. A measured peak gain of 6.13 dBic is achieved at 3.2 GHz.

Proceedings of the 16th Project Integration Meeting

NASA Technical Reports Server (NTRS)

Mcdonald, R. R.

1980-01-01

The principal achievement of the Low Cost Solar Array Project in 1980 was the attainment of $2.80/Wp Technical Readiness, and that processes and equipment now commercially available can make possible a deliverable product in 1982. A prototype array for intermediate load applications was demonstrated using frameless modules. It was proof tested to 40 lb/sq ft loading, and priced at $24/sq m, including array fabrication, module installation, shipping to the site and site installation for quantities of 20 MW.

Using EnviroAtlas Data to Identify Cost-Effective Locations for ...

EPA Pesticide Factsheets

Manure Management Use Case A use case walks through an example application of how EnviroAtlas data, in conjunction with other available data or resources, may be used to address real-world questions. Use cases may be hypothetical or based on actual cases where EnviroAtlas has been used in decision making at the local, regional or national scale. The use case is a deliverable for the EnviroAtlas project under the SHC 1.62 and will be incorporated on the EnviroAtlas website.

A New Tool for Effective and Efficient Project Management

DOE Office of Scientific and Technical Information (OSTI.GOV)

Willett, Jesse A

2011-12-01

Organizations routinely handle thousands of projects per year, and it is difficult to manage all these projects concurrently. Too often, projects do not get the attention they need when they need it. Management inattention can lead to late projects or projects with less than desirable content and/or deliverables. This paper discusses the application of Visual Project Management (VPM) as a method to track and manage projects. The VPM approach proved to be a powerful management tool without the overhead and restrictions of traditional management methods.

Applied statistical training to strengthen analysis and health research capacity in Rwanda.

PubMed

Thomson, Dana R; Semakula, Muhammed; Hirschhorn, Lisa R; Murray, Megan; Ndahindwa, Vedaste; Manzi, Anatole; Mukabutera, Assumpta; Karema, Corine; Condo, Jeanine; Hedt-Gauthier, Bethany

2016-09-29

To guide efficient investment of limited health resources in sub-Saharan Africa, local researchers need to be involved in, and guide, health system and policy research. While extensive survey and census data are available to health researchers and program officers in resource-limited countries, local involvement and leadership in research is limited due to inadequate experience, lack of dedicated research time and weak interagency connections, among other challenges. Many research-strengthening initiatives host prolonged fellowships out-of-country, yet their approaches have not been evaluated for effectiveness in involvement and development of local leadership in research. We developed, implemented and evaluated a multi-month, deliverable-driven, survey analysis training based in Rwanda to strengthen skills of five local research leaders, 15 statisticians, and a PhD candidate. Research leaders applied with a specific research question relevant to country challenges and committed to leading an analysis to publication. Statisticians with prerequisite statistical training and experience with a statistical software applied to participate in class-based trainings and complete an assigned analysis. Both statisticians and research leaders were provided ongoing in-country mentoring for analysis and manuscript writing. Participants reported a high level of skill, knowledge and collaborator development from class-based trainings and out-of-class mentorship that were sustained 1 year later. Five of six manuscripts were authored by multi-institution teams and submitted to international peer-reviewed scientific journals, and three-quarters of the participants mentored others in survey data analysis or conducted an additional survey analysis in the year following the training. Our model was effective in utilizing existing survey data and strengthening skills among full-time working professionals without disrupting ongoing work commitments and using few resources. Critical to our success were a transparent, robust application process and time limited training supplemented by ongoing, in-country mentoring toward manuscript deliverables that were led by Rwanda's health research leaders.

SafeLand guidelines for landslide monitoring and early warning systems in Europe - Design and required technology

NASA Astrophysics Data System (ADS)

Bazin, S.

2012-04-01

Landslide monitoring means the comparison of landslide characteristics like areal extent, speed of movement, surface topography and soil humidity from different periods in order to assess landslide activity. An ultimate "universal" methodology for this purpose does not exist; every technology has its own advantages and disadvantages. End-users should carefully consider each one to select the methodologies that represent the best compromise between pros and cons, and are best suited for their needs. Besides monitoring technology, there are many factors governing the choice of an Early Warning System (EWS). A people-centred EWS necessarily comprises five key elements: (1) knowledge of the risks; (2) identification, monitoring, analysis and forecasting of the hazards; (3) operational centre; (4) communication or dissemination of alerts and warnings; and (5) local capabilities to respond to the warnings received. The expression "end-to-end warning system" is also used to emphasize that EWSs need to span all steps from hazard detection through to community response. The aim of the present work is to provide guidelines for establishing the different components for landslide EWSs. One of the main deliverables of the EC-FP7 SafeLand project addresses the technical and practical issues related to monitoring and early warning for landslides, and identifies the best technologies available in the context of both hazard assessment and design of EWSs. This deliverable targets the end-users and aims to facilitate the decision process by providing guidelines. For the purpose of sharing the globally accumulated expertise, a screening study was done on 14 EWSs from 8 different countries. On these bases, the report presents a synoptic view of existing monitoring methodologies and early-warning strategies and their applicability for different landslide types, scales and risk management steps. Several comprehensive checklists and toolboxes are also included to support informed decisions. The deliverable was compiled with contributions from experts on landslides, monitoring technologies, remote sensing, and social researchers from 16 European institutions. The deliverable addresses one of the main objectives of the SafeLand project, namely to merge experience and expert judgment and create synergies on European level towards guidelines for early warning and to make these results available to end-users and local stakeholders.

Noise exposure and auditory thresholds of German airline pilots: a cross-sectional study

PubMed Central

Müller, Reinhard; Schneider, Joachim

2017-01-01

Objective The cockpit workplace of airline pilots is a noisy environment. This study examines the hearing thresholds of pilots with respect to ambient noise and communication sound. Methods The hearing of 487 German pilots was analysed by audiometry in the frequency range of 125 Hz–16 kHz in varying age groups. Cockpit noise (free-field) data and communication sound (acoustic manikin) measurements were evaluated. Results The ambient noise levels in cockpits were found to be between 74 and 80 dB(A), and the sound pressure levels under the headset were found to be between 84 and 88 dB(A). The left–right threshold differences at 3, 4 and 6 kHz show evidence of impaired hearing at the left ear, which worsens by age. In the age groups <40/≥40 years the mean differences at 3 kHz are 2/3 dB, at 4 kHz 2/4 dB and at 6 kHz 1/6 dB. In the pilot group which used mostly the left ear for communication tasks (43 of 45 are in the older age group) the mean difference at 3 kHz is 6 dB, at 4 kHz 7 dB and at 6 kHz 10 dB. The pilots who used the headset only at the right ear also show worse hearing at the left ear of 2 dB at 3 kHz, 3 dB at 4 kHz and at 6 kHz. The frequency-corrected exposure levels under the headset are 7–11 dB(A) higher than the ambient noise with an averaged signal-to-noise ratio for communication of about 10 dB(A). Conclusions The left ear seems to be more susceptible to hearing loss than the right ear. Active noise reduction systems allow for a reduced sound level for the communication signal below the upper exposure action value of 85 dB(A) and allow for a more relaxed working environment for pilots. PMID:28559452

REFAB: A Prototype Graphical Frontend for the RESA Naval Wargame

DTIC Science & Technology

1990-06-01

knots (dB) NBN - 6 0:999999 Signature line frequencies (Hz) 0:500 NB noise (dB) HFDF - I alphanumeric HFDF name DECM 1 YESINO DECEPTION (RADAR...dB) BBD3 - 1 0:500 BB @300 Hz noise at 05/10/15120/25/30 knots (dB) NBD - 6 0:999999 Signature line frequencies (Hz) 0:500 Diesel NB noise (dB) 48...Number Range of Values Description LFREQ 1 10:20000 Low end of band frequency (Hz) HFREQ 1 10:20000 High end of band frequency (Hz) HZBW 1 0:360

Alternative Fuels Data Center: ASTM Biodiesel Specifications

Science.gov Websites

purchased from ASTM International. Property Test Method Grade No.1-B S15 Grade No.1-B S500 Grade No.2-B S15 ASTM International. Property Test Method Grade B6 to B20 S15 B6 to B20 S500 j B6 to B20 S5000 Acid for the intended use and expected ambient temperatures. Test Methods D 4539 and D 6371 may be useful

UPLC-QTOF-MS/MS-guided isolation and purification of sulfur-containing derivatives from sulfur-fumigated edible herbs, a case study on ginseng.

PubMed

Zhang, Li; Shen, Hong; Xu, Jun; Xu, Jin-Di; Li, Zhen-Ling; Wu, Jie; Zou, Ye-Ting; Liu, Li-Fang; Li, Song-Lin

2018-04-25

In this study, a novel ultra-performance liquid chromatography coupled with quadrupole/time-of-flight mass spectrometry (UPLC-QTOF-MS/MS)-guidance strategy was proposed for preparation of sulfur-containing derivatives in sulfur-fumigated edible herbs. Being versatile in both chromatographic separation and mass spectrometric detection, UPLC-QTOF-MS/MS was inducted into each experimental step for multifaceted purposes including finding, tracking, purity determination and structural elucidation of targeted compounds as well as UPLC-HPLC chromatographic conditions transplantation, whereby the isolation and purification procedures were greatly facilitated. Using this strategy, a new sulfur-containing ginsenoside Rg 1 derivative (named compound I) was obtained from sulfur-fumigated ginseng. The chemical structure of compound I was elucidated to be (3β, 6α, 12β)-3, 12-dihydroxydammar-25-ene-6, 20-diylbis-β-d-glucopyranoside, 24-sulfonic acid by QTOF-MS/MS, 1 H-NMR and 13 C-NMR analysis, and its generation mechanisms by sulfur-fumigation were accordingly discussed. The research deliverable suggests that the UPLC-QTOF-MS/MS-guidance strategy is promising for targeted preparation of sulfur-containing derivatives from sulfur-fumigated edible herbs. Copyright © 2017 Elsevier Ltd. All rights reserved.

Design of the 1.5 MW, 30-96 MHz ultra-wideband 3 dB high power hybrid coupler for Ion Cyclotron Resonance Frequency (ICRF) heating in fusion grade reactor.

PubMed

Yadav, Rana Pratap; Kumar, Sunil; Kulkarni, S V

2016-01-01

Design and developmental procedure of strip-line based 1.5 MW, 30-96 MHz, ultra-wideband high power 3 dB hybrid coupler has been presented and its applicability in ion cyclotron resonance heating (ICRH) in tokamak is discussed. For the high power handling capability, spacing between conductors and ground need to very high. Hence other structural parameters like strip-width, strip thickness coupling gap, and junction also become large which can be gone upto optimum limit where various constrains like fabrication tolerance, discontinuities, and excitation of higher TE and TM modes become prominent and significantly deteriorates the desired parameters of the coupled lines system. In designed hybrid coupler, two 8.34 dB coupled lines are connected in tandem to get desired coupling of 3 dB and air is used as dielectric. The spacing between ground and conductors are taken as 0.164 m for 1.5 MW power handling capability. To have the desired spacing, each of 8.34 dB segments are designed with inner dimension of 3.6 × 1.0 × 40 cm where constraints have been significantly realized, compensated, and applied in designing of 1.5 MW hybrid coupler and presented in paper.

Design of the 1.5 MW, 30-96 MHz ultra-wideband 3 dB high power hybrid coupler for Ion Cyclotron Resonance Frequency (ICRF) heating in fusion grade reactor

NASA Astrophysics Data System (ADS)

Yadav, Rana Pratap; Kumar, Sunil; Kulkarni, S. V.

2016-01-01

Design and developmental procedure of strip-line based 1.5 MW, 30-96 MHz, ultra-wideband high power 3 dB hybrid coupler has been presented and its applicability in ion cyclotron resonance heating (ICRH) in tokamak is discussed. For the high power handling capability, spacing between conductors and ground need to very high. Hence other structural parameters like strip-width, strip thickness coupling gap, and junction also become large which can be gone upto optimum limit where various constrains like fabrication tolerance, discontinuities, and excitation of higher TE and TM modes become prominent and significantly deteriorates the desired parameters of the coupled lines system. In designed hybrid coupler, two 8.34 dB coupled lines are connected in tandem to get desired coupling of 3 dB and air is used as dielectric. The spacing between ground and conductors are taken as 0.164 m for 1.5 MW power handling capability. To have the desired spacing, each of 8.34 dB segments are designed with inner dimension of 3.6 × 1.0 × 40 cm where constraints have been significantly realized, compensated, and applied in designing of 1.5 MW hybrid coupler and presented in paper.

Hierarchical Topological Network Analysis of Anatomical Human Brain Connectivity and Differences Related to Sex and Kinship

DTIC Science & Technology

2011-10-01

Richiardi, J., Eryilmaz, H., Schwartz, S ., Vuilleumier, P., Van De Ville, D.,1499 2010. Decoding brain states from fmri connectivity graphs. Neuroimage1500...Differences Related to Sex and Kinship 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR( S ) 5d. PROJECT NUMBER 5e. TASK NUMBER...5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME( S ) AND ADDRESS(ES) University of Minnesota,Institute for Mathematics and Its Applications,207

Synthesis and XRD, FT-IR vibrational, UV-vis, and nonlinear optical exploration of novel tetra substituted imidazole derivatives: A synergistic experimental-computational analysis

NASA Astrophysics Data System (ADS)

Ahmad, Muhammad Saeed; Khalid, Muhammad; Shaheen, Muhammad Ashraf; Tahir, Muhammad Nawaz; Khan, Muhammad Usman; Braga, Ataualpa Albert Carmo; Shad, Hazoor Ahmad

2018-04-01

Heterocyclic compounds have potential applications in many fields of life. We synthesized novel tetra substituted imidazoles by four-component condensation of benzil, substituted aldehydes, substituted anilines and ammonium acetate as a source of ammonia and acetic acid as the solvent. Their chemical structures were resolved through X-ray crystallographic and spectroscopic (Fourier transform IR and UV-vis) techniques. In addition to experimental analysis, density functional theory (DFT) calculations at the B3LYP/6-311 + G(d,p) level were performed on 4-bromo-2-(1-(4-methoxyphenyl)-4,5-diphenyl-1H-imidazole-2-yl)phenol (1), 4-bromo-2-(1-(1-naphthalen-yl)-4,5-diphenyl-1H-imidazole-2-yl)phenol (2), and 2-(1-(2-chlorophenyl)-4,5-diphenyl-1-H-imidazole-2-yl)-6-methoxyphenol (3) to obtain the optimized geometry and spectroscopic (Fourier transform IR and UV-vis) and non-linear optical properties. Frontier molecular orbital analysis was performed at the Hartee-Fock/6-311+g(d,p) and DFT/B3LYP/6-311+G(d,p) levels of theory. Natural bond orbital (NBO) and UV-vis spectral analyses were performed at the M06-2X/6-31+G(d,p) and time-dependent DFT/B3LYP/6-311+G(d,p) levels, respectively. Overall, the DFT findings show good agreement with the experimental data. The hyper conjugative interaction network, which is responsible for the stability of compounds 1, 2 and 3 was explored by the NBO approach. The global reactivity parameters were explored with use of the energy of the frontier molecular orbitals. DFT calculations predict the first-order hyperpolarizabilities of compounds 1, 2 and 3 are 294.89 × 10-30, 219.45 × 10-30 and 146.77 × 10-30 esu, respectively. A two-state model was used to describe the non-linear optical properties of the compounds investigated.

75 FR 42455 - Novartis Pharmaceuticals Corp. et al.; Withdrawal of Approval of 27 New Drug Applications and 58...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-21

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2010-N-0318... NDA 6-008 Mesantoin (mephenytoin) Tablets Novartis Pharmaceuticals Corp., One Health Plaza, East... Endo Pharmaceuticals NDA 17-255 MPI DTPA Chelate multidose (kit for Medi-Physics, Inc., d/b/a GE...

Issues in Performance Measurement for Military Aviation with Applications to Air Combat Maneuvering

DTIC Science & Technology

1986-04-04

Systems Center 6c. ADDRESS (City, State, and ZIP Co*e) 7b. ADDRESS (City. State, and ZIP Code) 1040 Woodcock Road, Suite 227 Orlando, FL 32813-7100...NTSC TR-86-008 Vreuls, D., Obermayer, R. W., Goldstein, I. & Lauber, J. K. (1973). Measurement of trainee performance in a captive rotary- wing device

24 CFR 200.945 - Supplementary specific requirements under the HUD building product standards and certification...

Code of Federal Regulations, 2010 CFR

2010-04-01

... under the HUD building product standards and certification program for carpet. 200.945 Section 200.945... requirements under the HUD building product standards and certification program for carpet. (a) Applicable.... (b) Labeling. Under the procedures set forth in § 200.935(d)(6) concerning labeling of a product, the...

14 CFR 16.1 - Applicability and description of part.

Code of Federal Regulations, 2010 CFR

2010-01-01

...) The assurances contained in grant-in-aid agreements issued under the Airport and Airway Improvement...(a) and (b). (6) Section 505(d) of the Airport and Airway Improvement Act of 1982, as amended, 49 U.S... (49 U.S.C. 1723), or section 516 of the Airport and Airway Improvement Act (49 U.S.C. 47125). (8...

Problem-Solving Under Time Constraints: Alternatives for the Commander’s Estimate

DTIC Science & Technology

1990-03-26

CHOOL OF ADVANCED MILITAR (If applicable) STUDIES, USAC&GSC IATZL-SWV 6. ADDRESS (City, State, and ZIP Code ) 7b. ADDRESS (City, State, and ZIP Code ...NOTATION 17. COSATI CODES 18. SUBJECT TERMS (Continue on reverse if necessary and identify by block number) FIELD GROUP SUB-GROUP DECISIONJ*MAKING...OF RESPONSIBLE INDIVIDUAL 22b. TELEPHONE (Include Area Code ) 122c. OFFICE SYMBOL MAJ TIMOTHY D. LYNCH 9 684-3437 1 AT71-.qWV DO Form 1473, JUN 86

Assessment and Development of Oculomotor Flying Skills by the Application of the Channel Theory of Vision.

DTIC Science & Technology

1982-03-26

IT NUMBERSCentre for Research in Sensory Psychology and Medical Physics, Dalhousie University, Halifax, Nova. Scotia, Canada B3J IB6 JA...34Background" above has been developed 38 more extensively in an article for Psychological Review, and the implications for skilled eye-limb coordination are...Press. 4. Barlow , H., Blakemore, C.B. and Pettigrew, J.D. (1967) The neural mechanism of binocular depth discrimination. J. Physiol., Lond. 193, 327-342

Pyridoxic acid excretion during low vitamin B-6 intake, total fasting, and bed rest

NASA Technical Reports Server (NTRS)

Coburn, S. P.; Thampy, K. G.; Lane, H. W.; Conn, P. S.; Ziegler, P. J.; Costill, D. L.; Mahuren, J. D.; Fink, W. J.; Pearson, D. R.; Schaltenbrand, W. E.

1995-01-01

Vitamin B-6 metabolism in 10 volunteers during 21 d of total fasting was compared with results from 10 men consuming a diet low only in vitamin B-6 (1.76 mumol/d) and with men consuming a normal diet during bed rest. At the end of the fast mean plasma concentrations of vitamin B-6 metabolites and urinary excretion of 4-pyridoxic acid tended to be higher in the fasting subjects than in the low-vitamin B-6 group. The fasting subjects lost approximately 10% of their total vitamin B-6 pool and approximately 13% of their body weight. The low-vitamin B-6 group lost only approximately 4% of their vitamin B-6 pool. Compared with baseline, urinary excretion of pyridoxic acid was significantly increased during 17 wk of bed rest. There was no increase in pyridoxic acid excretion during a second 15-d bed rest study. These data suggest the possibility of complex interactions between diet and muscle metabolism that may influence indexes that are frequently used to assess vitamin B-6 status.

A Very Compact Rijndael S-box

DTIC Science & Technology

2005-05-17

6A 01101010 40 r8 107 6B 01101011 84 N4 108 6C 01101100 250 R 109 6D 01101101 133 s128 110 6E 01101110 61 S64 111 6F 01101111 186 n64 112 70 01110000...210 D2 11010010 132 l128 109 6D 01101101 133 s128 183 B7 10110111 134 C128 194 C2 11000010 135 T 128 93 5D 01011101 136 α8 231 E7 11100111 137 g128

A Systems Analysis and Design Case Study for a Business Modeling Learning Experience for a Capstone CIS/IS Systems Development Class

ERIC Educational Resources Information Center

Russell, Jack; Russell, Barbara

2015-01-01

The goal is to provide a robust and challenging problem statement for a capstone, advanced systems analysis and design course for CIS/MIS/CS majors. In addition to the problem narrative, a representative solution for much of the business modeling deliverables is presented using the UML paradigm. A structured analysis deliverable will be the topic…

The Additive Impact of Group and Individual Publicly Displayed Feedback: Examining Individual Response Patterns and Response Generalization in a Safe-Driving Occupational Intervention

ERIC Educational Resources Information Center

Ludwig, Timothy D.; Geller, E. Scott; Clarke, Steven W.

2010-01-01

Additive effects of publicly posting individual feedback following group goal-setting and feedback were evaluated. The turn-signal use of pizza deliverers was studied in a multiple baseline design across two pizza stores. After baseline observations, pizza deliverers voted on a group turn-signal goal and then received 4 weeks of group feedback on…

The Air Land Sea Bulletin. Issue No. 2006-2, May 2006

DTIC Science & Technology

2006-05-01

THE AIR LAND SEA BULLETIN Issue No. 2006-2 Air Land Sea Application (ALSA) Center May 2006 IN HOUSE Director’s Comments— Final Thoughts...4 US Air Force Predator UAVs Have Moved Into a More Overt Strike Role [Jane’s Defence Weekly Reprint] ........................6...SUBTITLE The Air Land Sea Bulletin. Issue No. 2006-2, May 2006 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT

Genetic mapping of common bunt resistance and plant height QTL in wheat.

PubMed

Singh, Arti; Knox, Ron E; DePauw, R M; Singh, A K; Cuthbert, R D; Kumar, S; Campbell, H L

2016-02-01

Breeding for field resistance to common bunt in wheat will need to account for multiple genes and epistatic and QTL by environment interactions. Loci associated with quantitative resistance to common bunt are co-localized with other beneficial traits including plant height and rust resistance. Common bunt, also known as stinking smut, is caused by seed borne fungi Tilletia tritici (Bjerk.) Wint. [syn. Tilletia caries (DC.) Tul.] and Tilletia laevis Kühn [syn. Tilletia foetida (Wallr.) Liro.]. Common bunt is known to cause grain yield and quality losses in wheat due to bunt ball formation and infestation of the grain. The objectives of this research were to identify and map quantitative trait loci (QTL) for common bunt resistance, to study the epistatic interactions between the identified QTL, and investigate the co-localization of bunt resistance with plant height. A population of 261 doubled haploid lines from the cross Carberry/AC Cadillac and checks were genotyped with polymorphic genome wide microsatellite and DArT(®) markers. The lines were grown in 2011, 2012, and 2013 in separate nurseries for common bunt incidence and height evaluation. AC Cadillac contributed a QTL (QCbt.spa-6D) for common bunt resistance on chromosome 6D at markers XwPt-1695, XwPt-672044, and XwPt-5114. Carberry contributed QTL for bunt resistance on chromosomes 1B (QCbt.spa-1B at XwPt743523) 4B (QCbt.spa-4B at XwPt-744434-Xwmc617), 4D (QCbt.spa-4D at XwPt-9747), 5B (QCbt.spa-5B at XtPt-3719) and 7D (QCbt.spa-7D at Xwmc273). Significant epistatic interactions were identified for percent bunt incidence between QCbt.spa-1B × QCbt.spa-4B and QCbt.spa-1B × QCbt.spa-6D, and QTL by environment interaction between QCbt.spa-1B × QCbt.spa-6D. Plant height QTL were found on chromosomes 4B (QPh.spa-4B) and 6D (QPh.spa-6D) that co-located with bunt resistance QTL. The identification of previously unreported common bunt resistance QTL (on chromosomes 4B, 4D and 7D), and new understanding of QTL × QTL interactions will facilitate marker-assisted breeding for common bunt resistance.

Piperolein B and piperchabamide D isolated from black pepper (Piper nigrum L.) as larvicidal compounds against the diamondback moth (Plutella xylostella).

PubMed

Hwang, Ki Seon; Kim, Young Kook; Park, Kee Woong; Kim, Young Tae

2017-08-01

There is growing demand for the development of alternative pest control agents that are effective as well as non-toxic to human health and the environment. Plant protection products derived from plant extracts are an eco-friendly alternative to synthetic pesticides. The aim of this study was to identify larvicidal compounds isolated from a natural source against Plutella xylostella L. In a larvicidal activity assay, several solvent fractions from the methanol extract of Piper nigrum L. fruit showed larvicidal effects against P. xylostella. Screening results indicated that chloroform extract was the most effective against P. xylostella larvae. Two compounds with insecticidal activity in the chloroform fraction were identified as piperolein B and piperchabamide D by spectroscopic analyses, including mass spectrometry and NMR, and by comparison to published data. At applications of 0.1 mg mL -1 concentration, piperolein B and piperchabamide D, respectively, induced 96.7 ± 5.8% and 79.2 ± 16.6% mortality rates of P. xylostella larvae 4 days post-application. Our results demonstrate that piperolein B and piperchabamide D isolated from P. nigrum are the major constituents of the extract demonstrating insecticidal properties for the control of P. xylostella larvae. These plant-derived compounds should become useful alternatives to synthetic chemicals after studying their insecticidal mechanisms. © 2017 Society of Chemical Industry. © 2017 Society of Chemical Industry.

Application of 3D reconstruction for surgical treatment of hepatic alveolar echinococcosis

PubMed Central

He, Yi-Biao; Bai, Lei; Aji, Tuerganaili; Jiang, Yi; Zhao, Jin-Ming; Zhang, Jin-Hui; Shao, Ying-Mei; Liu, Wen-Ya; Wen, Hao

2015-01-01

AIM: To evaluate the reliability and accuracy of three-dimensional (3D) reconstruction for liver resection in patients with hepatic alveolar echinococcosis (HAE). METHODS: One-hundred and six consecutive patients with HAE underwent hepatectomy at our hospital between May 2011 and January 2015. Fifty-nine patients underwent preoperative 3D reconstruction and “virtual” 3D liver resection before surgery (Group A). Another 47 patients used conventional imaging methods for preoperative assessment (Group B). Outcomes of hepatectomy were compared between the two groups. RESULTS: There was no significant difference in preoperative data between the two groups. Compared with patients in Group B, those in Group A had a significantly shorter operation time (227.1 ± 51.4 vs 304.6 ± 88.1 min; P < 0.05), less intraoperative blood loss (308.1 ± 135.4 vs 458.1 ± 175.4 mL; P < 0.05), and lower requirement for intraoperative blood transfusion (186.4 ± 169.6 vs 289.4 ± 199.2 mL; P < 0.05). Estimated resection liver volumes in both groups had good correlation with actual graft weight (Group A: r = 0.978; Group B: r = 0.960). There was a significant higher serum level of albumin in Group A (26.3 ± 5.9 vs 22.6 ± 4.3 g/L, P < 0.05). Other postoperative laboratory parameters (serum levels of aminotransferase and bilirubin; prothrombin time) and duration of postoperative hospital stay were similar. Sixteen complications occurred in Group A and 19 in Group B. All patients were followed for 3-46 (mean, 17.3) mo. There was no recurrence of lesions in Group A, but two recurrences in Group B. There were three deaths: two from cerebrovascular accident, and one from car accident. CONCLUSION: 3D reconstruction provides comprehensive and precise anatomical information for the liver. It also improves the chance of success and reduces the risk of hepatectomy in HAE. PMID:26401085

A monoclonal antibody against PDGF B-chain inhibits PDGF-induced DNA synthesis in C3H fibroblasts and prevents binding of PDGF to its receptor.

PubMed

Vassbotn, F S; Langeland, N; Hagen, I; Holmsen, H

1990-09-01

A monoclonal antibody (MAb 6D11) against platelet-derived growth factor (PDGF) was studied. We found that the MAb 6D11 in concentrations equimolar to PDGF blocked the [3H]thymidine incorporation in C3H/10T1/2 C18 fibroblasts stimulated by PDGF B-B and PDGF A-B. This inhibition was overcome by high doses of PDGF. The [3H]thymidine incorporation stimulated by other growth factors (aFGF, bFGF and bombesin) was not inhibited by the antibody. The MAb 6D11 blocked receptor binding of PDGF B-B, but not PDGF A-A. These findings suggest that the MAb 6D11 abolishes PDGF-induced DNA synthesis by blocking PDGF receptor binding. In this communication we demonstrate an isoform-specific monoclonal antibody against PDGF.

CPW-fed Circularly Polarized Slot Antenna with Small Gap and Stick-shaped Shorted Strip for UHF FRID Readers

NASA Astrophysics Data System (ADS)

Pan, Chien-Yuan; Su, Chum-Chieh; Yang, Wei-Lin

2018-04-01

A new circularly polarized (CP) slot antenna with a small gap and a stick-shaped shorted strip is presented. The proposed antenna has a sufficient bandwidth for ultrahigh frequency (UHF) radio-frequency identification (RFID) reader applications. The antenna structure consists of a rectangular slot with a small gap, a stick-shaped shorted strip and a 50 Ω coplanar waveguide (CPW) feedline with an asymmetrical ground plane. By using the stick -shaped shorted strip to disturb magnetic current distribution on the slot, the CP radiation can be generated. The measured results demonstrate that the proposed antenna can reach a 10 dB return loss impedance bandwidth of 14.1 % (894-1030 MHz) and a 3 dB axial ratio (AR) bandwidth of 6.4 % (910-970 MHz). The whole antenna size is 80 × 80 × 1.6 mm3.

40 CFR 437.46 - Pretreatment standards for existing sources (PSES)

Code of Federal Regulations, 2010 CFR

2010-07-01

... from subparts A, B, or C of this part may be subject to Multiple Wastestream Subcategory pretreatment standards representing the application of PSES set forth in paragraphs (b), (c), (d), or (e) of this section... applicable Multiple Wastestream Subcategory standards set forth in paragraphs (b), (c), (d) or (e) of this...

Computational Divided Differencing and Divided Difference Arithmetics

DTIC Science & Technology

2001-01-01

A 1t��923Ã@Zp &+7²; 2³)*[ tD ³ N+³µ´ AG6J@1t@ ´ FD62921t9+F3Ã@1t�B|B@�; G�62923TA衩V3T7+6R_\\ª;T7#�3ÃA"�?3z;¢6J7#�"�:8cb$@f8...3¢6J@ �2;¢�29<� @nPA1¢@�;¢;t��7E9;6d7+ 1q3 ¢6J@=Ft629<�d9@1t�2��@a6H7+1f3¢6J@Wət;73C58J@1t� 0 923¢� 0 @o7<AM@1t923Ã7+1 y v v Computational...92@17C 923Ã@�;@��B3¢6J@1f3¢6J@|8:92371t�^n / ! 7+6;¢�B|B@UC bU4UC 7+ 1q3 ¢6J@ 8¦92371t�^nB. 1 $¦7+6T;¢�B|B@ UC bU4UCA282@BA

A high SFDR 6-bit 20-MS/s SAR ADC based on time-domain comparator

NASA Astrophysics Data System (ADS)

Xue, Han; Hua, Fan; Qi, Wei; Huazhong, Yang

2013-08-01

This paper presents a 6-bit 20-MS/s high spurious-free dynamic range (SFDR) and low power successive approximation register analog to digital converter (SAR ADC) for the radio-frequency (RF) transceiver front-end, especially for wireless sensor network (WSN) applications. This ADC adopts the modified common-centroid symmetry layout and the successive approximation register reset circuit to improve the linearity and dynamic range. Prototyped in a 0.18-μm 1P6M CMOS technology, the ADC performs a peak SFDR of 55.32 dB and effective number of bits (ENOB) of 5.1 bit for 10 MS/s. At the sample rate of 20 MS/s and the Nyquist input frequency, the 47.39-dB SFDR and 4.6-ENOB are achieved. The differential nonlinearity (DNL) is less than 0.83 LSB and the integral nonlinearity (INL) is less than 0.82 LSB. The experimental results indicate that this SAR ADC consumes a total of 522 μW power and occupies 0.98 mm2.

Synthesis of fagopyritols A1 and B1 from D-chiro-inositol.

PubMed

Cid, M Belén; Alfonso, Francisco; Martín-Lomas, Manuel

2004-09-13

Fagopyritol A1 (3-O-alpha-d-galactopyranosyl-d-chiro-inositol) and fagopyritol B1 (2-O-alpha-d-galactopyranosyl-d-chiro-inositol) have been synthesized by glycosylation of the diequatorial diol 1,4,5,6-tetra-O-benzoyl-d-chiro-inositol, readily obtained from d-chiro-inositol, with 2,3,4,6-tetra-O-benzyl-d-galactopyranosyl trichloroacetimidate.

Using ICT techniques for improving mechatronic systems' dependability

NASA Astrophysics Data System (ADS)

Miron, Emanuel; Silva, João P. M. A.; Machado, José; Olaru, Dumitru; Prisacaru, Gheorghe

2013-10-01

The use of analysis techniques for industrial controller's analysis, such as Simulation and Formal Verification, is complex on industrial context. This complexity is due to the fact that such techniques require sometimes high investment in specific skilled human resources that have sufficient theoretical knowledge in those domains. This paper aims, mainly, to show that it is possible to obtain a timed automata model for formal verification purposes, considering the CAD model of a mechanical component. This systematic approach can be used, by companies, for the analysis of industrial controllers programs. For this purpose, it is discussed, in the paper, the best way to systematize these procedures, and this paper describes, only, the first step of a complex process and promotes a discussion of the main difficulties that can be found and a possibility for handle those difficulties. A library for formal verification purposes is obtained from original 3D CAD models using Software as a Service platform (SaaS) that, nowadays, has become a common deliverable model for many applications, because SaaS is typically accessed by users via internet access.

CDC/NACCHO Accreditation Support Initiative: advancing readiness for local and tribal health department accreditation.

PubMed

Monteiro, Erinn; Fisher, Jessica Solomon; Daub, Teresa; Zamperetti, Michelle Chuk

2014-01-01

Health departments have various unique needs that must be addressed in preparing for national accreditation. These needs require time and resources, shortages that many health departments face. The Accreditation Support Initiative's goal was to test the assumption that even small amounts of dedicated funding can help health departments make important progress in their readiness to apply for and achieve accreditation. Participating sites' scopes of work were unique to the needs of each site and based on the proposed activities outlined in their applications. Deliverables and various sources of data were collected from sites throughout the project period (December 2011-May 2012). Awardees included 1 tribal and 12 local health departments, as well as 5 organizations supporting the readiness of local and tribal health departments. Sites dedicated their funding toward staff time, accreditation fees, completion of documentation, and other accreditation readiness needs and produced a number of deliverables and example documents. All sites indicated that they made accreditation readiness gains that would not have occurred without this funding. Preliminary evaluation data from the first year of the Accreditation Support Initiative indicate that flexible funding arrangements may be an effective way to increase health departments' accreditation readiness.

Cost and Schedule Analytical Techniques Development

NASA Technical Reports Server (NTRS)

1998-01-01

This Final Report summarizes the activities performed by Science Applications International Corporation (SAIC) under contract NAS 8-40431 "Cost and Schedule Analytical Techniques Development Contract" (CSATD) during Option Year 3 (December 1, 1997 through November 30, 1998). This Final Report is in compliance with Paragraph 5 of Section F of the contract. This CSATD contract provides technical products and deliverables in the form of parametric models, databases, methodologies, studies, and analyses to the NASA Marshall Space Flight Center's (MSFC) Engineering Cost Office (PP03) and the Program Plans and Requirements Office (PP02) and other user organizations. Detailed Monthly Reports were submitted to MSFC in accordance with the contract's Statement of Work, Section IV "Reporting and Documentation". These reports spelled out each month's specific work performed, deliverables submitted, major meetings conducted, and other pertinent information. Therefore, this Final Report will summarize these activities at a higher level. During this contract Option Year, SAIC expended 25,745 hours in the performance of tasks called out in the Statement of Work. This represents approximately 14 full-time EPs. Included are the Huntsville-based team, plus SAIC specialists in San Diego, Ames Research Center, Tampa, and Colorado Springs performing specific tasks for which they are uniquely qualified.

Cost and Schedule Analytical Techniques Development: Option 2 Year

NASA Technical Reports Server (NTRS)

1997-01-01

This Final Report summarizes the activities performed by Science Applications International Corporation (SAIC) for the Option 2 Year from December 1, 1996 through November 30, 1997. The Final Report is in compliance with Paragraph 5 of Section F of the contract. This CSATD contract provides products and deliverable in the form of models, data bases, methodologies, studies and analyses for the NASA Marshall Space Flight Center's (MSFC) Engineering Cost Office (PPO3) the Program Plans and Requirements Officer (PP02), and other user organizations. Detailed Monthly Progress reports were submitted to MSFC in accordance with the contract's Statement of Work, Section TV "Reporting and Documentation". These reports spelled out each month's specific work accomplishments, deliverables submitted, major meetings held, and other pertinent information. This Final Report will summarize these activities at higher level. During this contract Option Year, SAIC expended 29,830 man-hours in tile performance of tasks called out in the Statement of Work and reported oil in this yearly Final Report. This represents approximately 16 full-time EPs. Included are the basis Huntsville-based team, plus SAIC specialists in San Diego, Ames Research Center, Chicago, and Colorado Springs performing specific tasks for which they are uniquely qualified.

Michales AAF, Dugway, Utah. Revised Uniform Summary of Surface Weather Observations (RUSSWO). Parts A - F

DTIC Science & Technology

1974-03-21

We, Boi Do. o 90/ 89 . -- -- - -A lt eI -- ... .. -- .- -"a___ ..... J __v a L_:I 4 4.56/ 81 Io 1 31 . I- ,5"z l .2 6 26 ,_. __ll5 , , ._. .3 1 2...30 31 D.B./W.B. v),, 00,16W., d.16s Des Porn , " ,.b/ 15 I _..- -i7 12/1- - - r- - - t . .... -9 1 6 I’ TOTAL . 2. . . . ... .... -55 1. .9 .2 .1...3. 4f . { . 14. 1015 1S~6 17 - 18119.- 20 21,-22123.2- 2 8 9 30 j1D.B.’W.B. Dry Bulb] Wt 6u.b6[5-a Porn ’ 60/ 59 - Iti!I I-./’ ’ ’ ’ ’ t- - " 5 1

Dual-Modality Prostate Imaging with PET and Transrectal Ultrasound

DTIC Science & Technology

2009-04-01

TD (e<@?<K(a4S6(<B8R<%R(#M(A$#@Ŝ"&(*8%*&$(Q@<%R(*8$=#%0>>0 *?#:<%&Kb(!"#$%&"’()K(F#:D(JIK(AAD...1( BBD (\\=](O#N<M<&N(;SO!(^a4&$M#$B8%*&(O&8@Q$&B&%"@(#M(4#@<"$#%(SB<@@<#%( 6#B#R$8A?@Kb(;8"<#%8:(S:&*"$<*8:(O8%QM8*"Q$&$@(!@@#*ɠ"<#%(\\;SO!](V&A...34<#%(<%("?&(=8*+R$#Q%N(A&:F<@($&R<#%D(.B8R&( $&A$&@&%"@(GJG(O(*#Q%"@(\\+-(-=(13(B<%Q"&@(#M(N8Ŝ]D(6?&(F#Z&:(@<j&(<@(>D2W(BB(Z(>D2W(BB(Z(JD>J( BBD

Oral Application of Magnesium-L-Threonate Attenuates Vincristine-induced Allodynia and Hyperalgesia by Normalization of Tumor Necrosis Factor-α/Nuclear Factor-κB Signaling.

PubMed

Xu, Ting; Li, Dai; Zhou, Xin; Ouyang, Han-Dong; Zhou, Li-Jun; Zhou, Hang; Zhang, Hong-Mei; Wei, Xu-Hong; Liu, Guosong; Liu, Xian-Guo

2017-06-01

Antineoplastic agents, including vincristine, often induce neuropathic pain and magnesium deficiency clinically, but the causal link between them has not been determined. No drug is available for treating this form of neuropathic pain. Injection of vincristine (0.1 mg · kg · day, intraperitoneally, for 10 days) was used to induce nociceptive sensitization, which was accessed with von Frey hairs and the plantar tester in adult male Sprague-Dawley rats. Magnesium-L- threonate was administered through drinking water (604 mg · kg · day). Extracellular and intracellular free Mg were measured by Calmagite chromometry and flow cytometry. Molecular biologic and electrophysiologic experiments were performed to expose the underlying mechanisms. Vincristine injection induced allodynia and hyperalgesia (n = 12), activated tumor necrosis factor-α/nuclear factor-κB signaling, and reduced free Mg in cerebrospinal fluid by 21.7 ± 6.3% (mean ± SD; n = 13) and in dorsal root ganglion neurons by 27 ± 6% (n = 11). Reducing Mg activated tumor necrosis factor-α/nuclear factor-κB signaling in cultured dorsal root ganglion neurons. Oral application of magnesium-L-threonate prevented magnesium deficiency and attenuated both activation of tumor necrosis factor-α/nuclear factor-κB signaling and nociceptive sensitization (n = 12). Mechanistically, vincristine induced long-term potentiation at C-fiber synapses, up-regulated N-methyl-D-aspartate receptor type 2B subunit of N-methyl-D-aspartate receptor, and led to peptidergic C-fiber sprouting in spinal dorsal horn (n = 6 each). The vincristine-induced pathologic plasticity was blocked by intrathecal injection of nuclear factor-κB inhibitor (n = 6), mimicked by tumor necrosis factor-α, and substantially prevented by oral magnesium-L-threonate (n = 5). Vincristine may activate tumor necrosis factor-α/nuclear factor-κB pathway by reduction of intracellular magnesium, leading to spinal pathologic plasticity and nociceptive sensitization. Oral magnesium-L-threonate that prevents the magnesium deficiency is a novel approach to prevent neuropathic pain induced by chemotherapy.

Hydrogen/deuterium exchange, a unique and effective method for MS fragmentation behavior elucidation of ginkgolides and its application to systematic research in Ginkgo biloba.

PubMed

Niu, Xingliang; Luo, Jun; Xu, Deran; Zou, Hongyan; Kong, Lingyi

2017-02-05

Ginkgolides, the main active constituents of Ginkgo biloba, possess significant selectively inhibition on platelet-activating factor and pancreatic lipase and attract wide attention in pharmacological research area. In our study, an effective hydrogen/deuterium (H/D) exchange method was developed by exchanging the α-Hs of lactone groups in ginkgolides with Ds, which was very useful for the elucidation of the fragmentation patterns of ginkgolides in Quadrupole Time-of-flight Mass Spectrometry (Q-TOF-MS), especially in accurately distinguishing the type and position of substituent in framework of ginkgolides. Then, a systematic research strategy for qualitative and quantitative analysis of ginkgolides, based on H/D exchange, tandem solid-phase extraction and LC-Q-TOF-MS, was developed, which was successfully applied in each medicinal part of G. biloba, which indicated that ginkgolide B was the most abundant ginkgolide in the seeds of G. biloba (60.6μg/g). This research was the successful application of H/D exchange in natural products, and proved that H/D exchange is a potential method for analysis research of complex TCMs active constituents. Copyright © 2016 Elsevier B.V. All rights reserved.

NLOphoric rigid pyrazino-phenanthroline donor-π-acceptor compounds: Investigation of structural and solvent effects on non-linear optical properties using computational methods

NASA Astrophysics Data System (ADS)

Kothavale, Shantaram; Katariya, Santosh; Sekar, Nagaiyan

2018-01-01

Rigid pyrazino-phenanthroline based donor-π-acceptor-π-auxiliary acceptor type compounds have been studied for their linear and non-linear optical properties. The non-linear optical (NLO) behavior of these dyes was studied by calculating the values of static α , β and γ using solvatochromic as well as computational methods. The results obtained by solvatochromic method are correlated theoretically with Density Functional Theory (DFT) using B3LYP/6-31G (d), CAM B3LYP/6-31 G(d), B3LYP/6-31++ g(d,P) and CAM B3LYP/6-31++ g(d,P) methods. The results reveal that, among all four computational methods CAM-B3LYP/6-31++ g(d,P) performs well for the calculation of linear polarizability (α) and first order hyperpolarizability (β), while CAM-B3LYP/6-31 g(d,P) for the calculation of second order hyperpolarizability (ϒ). Overall TPA depends on the molecular structure variation with increase in complexity and molecular weight, which implies that both the number of branches and the size of π-framework are important factors for the molecular TPA in this chromophoric system. Generalized Mulliken-Hush (GMH) analysis is performed to study the effective charge transfer from donor to acceptor.

Atomically thin layers of B-N-C-O with tunable composition.

PubMed

Ozturk, Birol; de-Luna-Bugallo, Andres; Panaitescu, Eugen; Chiaramonti, Ann N; Liu, Fangze; Vargas, Anthony; Jiang, Xueping; Kharche, Neerav; Yavuzcetin, Ozgur; Alnaji, Majed; Ford, Matthew J; Lok, Jay; Zhao, Yongyi; King, Nicholas; Dhar, Nibir K; Dubey, Madan; Nayak, Saroj K; Sridhar, Srinivas; Kar, Swastik

2015-07-01

In recent times, atomically thin alloys of boron, nitrogen, and carbon have generated significant excitement as a composition-tunable two-dimensional (2D) material that demonstrates rich physics as well as application potentials. The possibility of tunably incorporating oxygen, a group VI element, into the honeycomb sp(2)-type 2D-BNC lattice is an intriguing idea from both fundamental and applied perspectives. We present the first report on an atomically thin quaternary alloy of boron, nitrogen, carbon, and oxygen (2D-BNCO). Our experiments suggest, and density functional theory (DFT) calculations corroborate, stable configurations of a honeycomb 2D-BNCO lattice. We observe micrometer-scale 2D-BNCO domains within a graphene-rich 2D-BNC matrix, and are able to control the area coverage and relative composition of these domains by varying the oxygen content in the growth setup. Macroscopic samples comprising 2D-BNCO domains in a graphene-rich 2D-BNC matrix show graphene-like gate-modulated electronic transport with mobility exceeding 500 cm(2) V(-1) s(-1), and Arrhenius-like activated temperature dependence. Spin-polarized DFT calculations for nanoscale 2D-BNCO patches predict magnetic ground states originating from the B atoms closest to the O atoms and sizable (0.6 eV < E g < 0.8 eV) band gaps in their density of states. These results suggest that 2D-BNCO with novel electronic and magnetic properties have great potential for nanoelectronics and spintronic applications in an atomically thin platform.

Performance Analysis of Polymorphous Computing Architectures

DTIC Science & Technology

2001-01-01

G H F Proc 5 : 4 : 3 11 1 Figure 3. Self-timed execution. D C B F G H E D B H EA CG...F D C B F G H E D B H EA CG F AProc 1 Proc 2 Proc 3 Proc 4 Proc 5 185 cution pattern when the application graph in Figure 2 is executed in a self...transform, a quadra- E Figure 10. Self-timed execution with first-iteration actors denoted by T. D B H E CG F D C B F G H E D B H EA CG F A 18 T T T

H2 Control of Natural T Regulatory Cell Frequency in the Lymph Node Correlates with Susceptibility to Day Three Thymectomy Induced Autoimmune Disease

PubMed Central

Rio, Roxana del; Sun, Yuefang; Alard, Pascale; Tung, Kenneth S.K.; Teuscher, Cory

2010-01-01

Day 3 thymectomy (D3Tx) results in a loss of peripheral tolerance mediated by natural T regulatory cells (nTR) and development of autoimmune ovarian dysgenesis (AOD) and dacryoadenitis (ADA) in A/J and (C57BL/6J × A/J) F1 hybrids (B6A) but not in C57BL/6J (B6) mice. Previously, using quantitative trait locus (QTL) linkage analysis, we showed that D3Tx-AOD is controlled by five unlinked QTL (Aod1-Aod5) and H2. In the present study, using D3Tx B6-ChrA/J/NaJ chromosome substitution strains, we confirm that QTL on chromosome (Chr) 16 (Aod1a/Aod1b), Chr3 (Aod2), Chr1 (Aod3), Chr2 (Aod4), Chr7 (Aod5), and Chr17 (H2) control D3Tx-AOD susceptibility. Additionally, we present the first data mapping QTL controlling D3Tx-ADA to Chr17 (Ada1/H2), Chr1 (Ada2), and Chr3 (Ada3). Importantly, B6-ChrXA/J mice were as resistant to D3Tx-AOD and D3Tx-ADA as B6 mice thereby excluding Foxp3 as a susceptibility gene in these models. Moreover, we report quantitative differences in the frequency of nTR cells in the lymph nodes (LNs), but not spleen or thymus, of AOD/ADA-resistant B6 and AOD/ADA-susceptible A/J, B6A, and B6-Chr17A/J mice. Similar results correlating with experimental allergic encephalomyelitis and orchitis susceptibility were seen with B10.S and SJL/J mice. Using H2-congenic mice we show that the observed difference in frequency of LN nTR cells is controlled by H2. These data support the existence of a LN-specific, H2-controlled mechanism regulating the prevalence of nTR cells in autoimmune disease susceptibility. PMID:21135167

Simultaneous optimization of photons and electrons for mixed beam radiotherapy

NASA Astrophysics Data System (ADS)

Mueller, S.; Fix, M. K.; Joosten, A.; Henzen, D.; Frei, D.; Volken, W.; Kueng, R.; Aebersold, D. M.; Stampanoni, M. F. M.; Manser, P.

2017-07-01

The aim of this work is to develop and investigate an inverse treatment planning process (TPP) for mixed beam radiotherapy (MBRT) capable of performing simultaneous optimization of photon and electron apertures. A simulated annealing based direct aperture optimization (DAO) is implemented to perform simultaneous optimization of photon and electron apertures, both shaped with the photon multileaf collimator (pMLC). Validated beam models are used as input for Monte Carlo dose calculations. Consideration of photon pMLC transmission during DAO and a weight re-optimization of the apertures after deliverable dose calculation are utilized to efficiently reduce the differences between optimized and deliverable dose distributions. The TPP for MBRT is evaluated for an academic situation with a superficial and an enlarged PTV in the depth, a left chest wall case including the internal mammary chain and a squamous cell carcinoma case. Deliverable dose distributions of MBRT plans are compared to those of modulated electron radiotherapy (MERT), photon IMRT and if available to those of clinical VMAT plans. The generated MBRT plans dosimetrically outperform the MERT, photon IMRT and VMAT plans for all investigated situations. For the clinical cases of the left chest wall and the squamous cell carcinoma, the MBRT plans cover the PTV similarly or more homogeneously than the VMAT plans, while OARs are spared considerably better with average reductions of the mean dose to parallel OARs and D 2% to serial OARs by 54% and 26%, respectively. Moreover, the low dose bath expressed as V 10% to normal tissue is substantially reduced by up to 45% compared to the VMAT plans. A TPP for MBRT including simultaneous optimization is successfully implemented and the dosimetric superiority of MBRT plans over MERT, photon IMRT and VMAT plans is demonstrated for academic and clinical situations including superficial targets with and without deep-seated part.

Simultaneous optimization of photons and electrons for mixed beam radiotherapy.

PubMed

Mueller, S; Fix, M K; Joosten, A; Henzen, D; Frei, D; Volken, W; Kueng, R; Aebersold, D M; Stampanoni, M F M; Manser, P

2017-06-26

The aim of this work is to develop and investigate an inverse treatment planning process (TPP) for mixed beam radiotherapy (MBRT) capable of performing simultaneous optimization of photon and electron apertures. A simulated annealing based direct aperture optimization (DAO) is implemented to perform simultaneous optimization of photon and electron apertures, both shaped with the photon multileaf collimator (pMLC). Validated beam models are used as input for Monte Carlo dose calculations. Consideration of photon pMLC transmission during DAO and a weight re-optimization of the apertures after deliverable dose calculation are utilized to efficiently reduce the differences between optimized and deliverable dose distributions. The TPP for MBRT is evaluated for an academic situation with a superficial and an enlarged PTV in the depth, a left chest wall case including the internal mammary chain and a squamous cell carcinoma case. Deliverable dose distributions of MBRT plans are compared to those of modulated electron radiotherapy (MERT), photon IMRT and if available to those of clinical VMAT plans. The generated MBRT plans dosimetrically outperform the MERT, photon IMRT and VMAT plans for all investigated situations. For the clinical cases of the left chest wall and the squamous cell carcinoma, the MBRT plans cover the PTV similarly or more homogeneously than the VMAT plans, while OARs are spared considerably better with average reductions of the mean dose to parallel OARs and D 2% to serial OARs by 54% and 26%, respectively. Moreover, the low dose bath expressed as V 10% to normal tissue is substantially reduced by up to 45% compared to the VMAT plans. A TPP for MBRT including simultaneous optimization is successfully implemented and the dosimetric superiority of MBRT plans over MERT, photon IMRT and VMAT plans is demonstrated for academic and clinical situations including superficial targets with and without deep-seated part.

Characterization of powdered fish heads for bone graft biomaterial applications.

PubMed

Oteyaka, Mustafa Ozgür; Unal, Hasan Hüseyin; Bilici, Namık; Taşçı, Eda

2013-01-01

The aim of this study was to define the chemical composition, morphology and crystallography of powdered fish heads of the species Argyrosomus regius for bone graft biomaterial applications. Two sizes of powder were prepared by different grinding methods; Powder A (coarse, d50=68.5 µm) and Powder B (fine, d50=19.1 µm). Samples were analyzed using X-ray diffraction (XRD), X-ray fluorescence (XRF), scanning electron microscopy (SEM), thermogravimetry (TG), and energy dispersive X-ray spectroscopy (EDS). The powder was mainly composed of aragonite (CaCO3) and calcite (CaCO3). The XRD pattern of Powder A and B matched standard aragonite and calcite patterns. In addition, the calcium oxide (CaO) phase was found after the calcination of Powder A. Thermogravimetry analysis confirmed total mass losses of 43.6% and 47.3% in Powders A and B, respectively. The microstructure of Powder A was mainly composed of different sizes and tubular shape, whereas Powder B showed agglomerated particles. The high quantity of CaO and other oxides resemble the chemical composition of bone. In general, the powder can be considered as bone graft after transformation to hydroxyapatite phase.

Resonant excited UV luminescence of the Gd3+ centres in borate glasses, co-doped with Gd and Ag

NASA Astrophysics Data System (ADS)

Padlyak, B. V.; Drzewiecki, A.; Padlyak, T. B.; Adamiv, V. T.; Teslyuk, I. M.

2018-05-01

The Li2B4O7:Gd, CaB4O7:Gd, LiCaBO3:Gd, and Li2B4O7:Gd, Ag glasses of high optical quality, obtained by standard technology, have been investigated by electron paramagnetic resonance (EPR) and optical spectroscopy at room temperature. The Gd impurity was added in the raw materials as Gd2O3 oxide in amounts 0.5 and 1.0 mol.%. The Ag impurity was introduced into the Li2B4O7 composition as AgNO3 and as highly dispersed metallic Ag in amount 2.0 mol.%. In all Gd-doped glasses was observed typical for glasses EPR U-spectrum of the Gd3+ (8S7/2, 4f7) ions. In the Gd-doped glasses upon the 273 nm excitation was observed weak UV emission line at 311 nm that is attributed to the 6P7/2 → 8S7/2 intraconfiguration 4f - 4f transition of the Gd3+ ions. In the Li2B4O7:Gd, Ag glass has been observed significant (∼100 times) increasing of peak intensity of the Gd3+ emission line at 311 nm in comparison with this line in CaB4O7:Gd glass. In luminescence excitation spectra of the CaB4O7:Gd and Li2B4O7:Gd, Ag glasses are observed characteristic groups of lines corresponding to the 8S7/2 → 6IJ, 6DJ transitions of the Gd3+ ions. Significant increasing of the Gd3+ emission line at 311 nm in the Li2B4O7:Gd, Ag glass is explained by energy transfer from Ag+ (4d10) to Gd3+ (4f7) upon 273 nm excitation that is resonant for 4d10 → 4d9 5s1 (1S0 → 1D2) and 8S7/2 → 6IJ transitions of the Ag+ and Gd3+ ions. Luminescence kinetics of the Gd3+ and Ag+ centres was investigated and analysed. Obtained results show that the borate glasses, co-activated by Gd3+ and Ag+, can be promising materials for effective UVB light sources for biomedical applications.

Hearing results using the SMart piston prosthesis.

PubMed

Fayad, Jose N; Semaan, Maroun T; Meier, Josh C; House, John W

2009-12-01

SMart, a newly introduced piston prosthesis for stapedotomy, is a nitinol-based, heat-activated, self-crimping prosthesis. We review our hearing results and postoperative complications using this self-crimped piston prosthesis and compare them with those obtained using stainless steel or platinum piston prostheses. Audiometric results using the SMart piston are identical to those obtained using a conventional piston prosthesis. Retrospective chart review. Private neurotologic tertiary referral center. The 416 ears reviewed included 306 with a SMart prosthesis and 110 conventional prostheses. 61% were women. Mean follow-up time was 5.6 (standard deviation [SD], 6.3 mo) and 6.9 months (SD, 7.0 mo) for the 2 groups, respectively. Stapedotomy using the SMart or a conventional (non-SMart) prosthesis. Audiometric hearing results, including pure-tone average (PTA) and air-bone gap (ABG), and prevalence of postoperative complications. Mean postoperative PTA was 32.6 (SD, 16.8) dB for the SMart group and 29.4 (SD, 13.5) dB for the non-SMart group, with ABGs of 7.6 (SD, 8.9) and 6.0 (SD, 5.2) dB, respectively. Mean change (decrease) in ABG was 18.7 (SD, 13.1) dB for the SMart group and 19.9 (SD, 10.3) dB for the non-SMart group. High-frequency bone PTAs showed overclosure of 2.0 (SD, 7.9) dB for the SMart group and 3.6 (SD, 8.6) dB for the non-SMart group. Postoperative vertigo and tinnitus were infrequent. No significant differences in these audiometric outcomes or complication rates were noted between groups. There was no significant difference in rate of gap closure to within 10 dB (78.3 versus 84.2%, SMart and non-SMart, respectively) or 20 dB (94.2 and 98.0%). Compared with conventional stapes prostheses, the nitinol-based SMart is a safe and reliable stapes prosthesis that eliminates manual crimping without significantly altering the audiometric outcome. Complications are rare, but longer follow-up is needed before establishing long-term stability.

Realization of Miniaturized Multi-/Wideband Microwave Front-Ends

NASA Astrophysics Data System (ADS)

Al Shamaileh, Khair A.

The ever-growing demand toward designing microwave front-end components with enhanced access to the radio spectrum (e.g., multi-/wideband functionality) and improved physical features (e.g., miniaturized circuitry, ease and cost of fabrication) is becoming more paramount than ever before. This dissertation proposes new design methodologies, simulations, and experimental validations of passive front-ends (i.e., antennas, couplers, dividers) at microwave frequencies. The presented design concepts optimize both electrical and physical characteristics without degrading the intended performance. The developed designs are essential to the upcoming wireless technologies. The first proposed component is a compact ultra-wideband (UWB) Wilkinson power divider (WPD). The design procedure is accomplished by replacing the uniform transmission lines in each arm of the conventional single-frequency divider with impedance-varying profiles governed by a truncated Fourier series. While such non-uniform transmission lines (NTLs) are obtained through the even-mode analysis, three isolation resistors are optimized in the odd-mode circuit to achieve proper isolation and output ports matching over the frequency range of interest. The proposed design methodology is systematic, and results in single-layered and compact structures. For verification purposes, an equal split WPD is designed, simulated, and measured. The obtained results show that the input and output ports matching as well as the isolation between the output ports are below --10 dB; whereas the transmission parameters vary between --3.2 dB and --5 dB across the 3.1--10.6 GHz band. The designed divider is expected to find applications in UWB antenna diversity, multiple-input-multiple-output (MIMO) schemes, and antenna arrays feeding networks. The second proposed component is a wideband multi-way Bagley power divider (BPD). Wideband functionality is achieved by replacing the single-frequency matching uniform microstrip lines in the conventional design with NTLs of wideband matching nature. To bring this concept into practice, the equivalent transmission line model is used for profiling impedance variations. The proposed technique leads to flexible spectrum allocation and matching level. Moreover, the resulting structures are compact and planar. First, the analytical results of three 3-way BPDs of different fractional bandwidths are presented and discussed to validate the proposed approach. Then, two examples of 3- and 5-way BPDs with bandwidths of 4--10 GHz and 5--9 GHz, respectively, are simulated, fabricated, and measured. Simulated and measured results show an acceptable input port matching of below --15 dB and --12.5 dB for the 3- and 5-way dividers, respectively, over the bands of interest. The resulting transmission parameters of the 3- and 5-way dividers are --4.77+/-;1 dB and --7+/-1 dB, respectively, over the design bands; which are in close proximity to their theoretical values. The proposed wideband BPD dividers find many applications in microwave front-end circuitry, especially in only-transmitting antenna subsystems, such as multi-/broad-cast communications, where neither output ports matching nor isolation is a necessity. The third proposed component is a 90° hybrid branch-line coupler (BLC) with multi-/wideband frequency matching. To obtain a multi-frequency operation, NTLs of lengths equal to those in the conventional design are incorporated through the even- and odd-mode analysis. The proposed structure is relatively simple and is fabricated on a single-layered substrate. Two design examples of dual-/triple-frequency BLCs suitable for GSM, WLAN, and Wi-Fi applications are designed, fabricated and evaluated experimentally to validate the proposed methodology. The same concept is extended to realize a broadband BLC with arbitrary coupling levels. Based on how impedances are profiled, the fractional bandwidth of a single-section 90° 3-dB BLC is extended to 57%, and the realization of broadband BLCs with predefined coupling levels is also achieved. Furthermore, higher-order harmonics are suppressed by enforcing BLC S-parameters to match design requirements only at a given frequency range. Three examples of 3-dB, 6-dB, and 9-dB BLCs are demonstrated at 3 GHz center frequency. The obtained analytical response, EM simulations, and measurements justify the design concept. The fourth proposed component is an UWB antipodal Vivaldi antenna (AVA) with high-Q stopband characteristics based on compact electromagnetic bandgap (EBG) structures. First, an AVA is designed and optimized to operate over an UWB spectrum. Then, two pairs of EBG cells are introduced along the antenna feed-line to suppress the frequency components at 3.6--3.9 and 5.6--5.8 GHz (i.e., WiMAX and ISM bands, respectively). Simulated and measured voltage standing wave ratio (VSWR) are below 2 for the entire 3.1--10.6 GHz band with high attenuation at the two selected sub-bands. This simple yet effective approach eliminates the need to deform the antenna radiators with slots/parasitic elements or comprise multilayer substrates.

Crystal Structure and Substrate Specificity of D-Galactose-6-Phosphate Isomerase Complexed with Substrates

PubMed Central

Lee, Jung-Kul; Pan, Cheol-Ho

2013-01-01

D-Galactose-6-phosphate isomerase from Lactobacillus rhamnosus (LacAB; EC 5.3.1.26), which is encoded by the tagatose-6-phosphate pathway gene cluster (lacABCD), catalyzes the isomerization of D-galactose-6-phosphate to D-tagatose-6-phosphate during lactose catabolism and is used to produce rare sugars as low-calorie natural sweeteners. The crystal structures of LacAB and its complex with D-tagatose-6-phosphate revealed that LacAB is a homotetramer of LacA and LacB subunits, with a structure similar to that of ribose-5-phosphate isomerase (Rpi). Structurally, LacAB belongs to the RpiB/LacAB superfamily, having a Rossmann-like αβα sandwich fold as has been identified in pentose phosphate isomerase and hexose phosphate isomerase. In contrast to other family members, the LacB subunit also has a unique α7 helix in its C-terminus. One active site is distinctly located at the interface between LacA and LacB, whereas two active sites are present in RpiB. In the structure of the product complex, the phosphate group of D-tagatose-6-phosphate is bound to three arginine residues, including Arg-39, producing a different substrate orientation than that in RpiB, where the substrate binds at Asp-43. Due to the proximity of the Arg-134 residue and backbone Cα of the α6 helix in LacA to the last Asp-172 residue of LacB with a hydrogen bond, a six-carbon sugar-phosphate can bind in the larger pocket of LacAB, compared with RpiB. His-96 in the active site is important for ring opening and substrate orientation, and Cys-65 is essential for the isomerization activity of the enzyme. Two rare sugar substrates, D-psicose and D-ribulose, show optimal binding in the LacAB-substrate complex. These findings were supported by the results of LacA activity assays. PMID:24015281

A geometrical correction for the inter- and intra-molecular basis set superposition error in Hartree-Fock and density functional theory calculations for large systems

NASA Astrophysics Data System (ADS)

Kruse, Holger; Grimme, Stefan

2012-04-01

A semi-empirical counterpoise-type correction for basis set superposition error (BSSE) in molecular systems is presented. An atom pair-wise potential corrects for the inter- and intra-molecular BSSE in supermolecular Hartree-Fock (HF) or density functional theory (DFT) calculations. This geometrical counterpoise (gCP) denoted scheme depends only on the molecular geometry, i.e., no input from the electronic wave-function is required and hence is applicable to molecules with ten thousands of atoms. The four necessary parameters have been determined by a fit to standard Boys and Bernadi counterpoise corrections for Hobza's S66×8 set of non-covalently bound complexes (528 data points). The method's target are small basis sets (e.g., minimal, split-valence, 6-31G*), but reliable results are also obtained for larger triple-ζ sets. The intermolecular BSSE is calculated by gCP within a typical error of 10%-30% that proves sufficient in many practical applications. The approach is suggested as a quantitative correction in production work and can also be routinely applied to estimate the magnitude of the BSSE beforehand. The applicability for biomolecules as the primary target is tested for the crambin protein, where gCP removes intramolecular BSSE effectively and yields conformational energies comparable to def2-TZVP basis results. Good mutual agreement is also found with Jensen's ACP(4) scheme, estimating the intramolecular BSSE in the phenylalanine-glycine-phenylalanine tripeptide, for which also a relaxed rotational energy profile is presented. A variety of minimal and double-ζ basis sets combined with gCP and the dispersion corrections DFT-D3 and DFT-NL are successfully benchmarked on the S22 and S66 sets of non-covalent interactions. Outstanding performance with a mean absolute deviation (MAD) of 0.51 kcal/mol (0.38 kcal/mol after D3-refit) is obtained at the gCP-corrected HF-D3/(minimal basis) level for the S66 benchmark. The gCP-corrected B3LYP-D3/6-31G* model chemistry yields MAD=0.68 kcal/mol, which represents a huge improvement over plain B3LYP/6-31G* (MAD=2.3 kcal/mol). Application of gCP-corrected B97-D3 and HF-D3 on a set of large protein-ligand complexes prove the robustness of the method. Analytical gCP gradients make optimizations of large systems feasible with small basis sets, as demonstrated for the inter-ring distances of 9-helicene and most of the complexes in Hobza's S22 test set. The method is implemented in a freely available FORTRAN program obtainable from the author's website.

Bioactive constituents from Chinese natural medicines. XXXII. aminopeptidase N and aldose reductase inhibitors from Sinocrassula indica: structures of sinocrassosides B(4), B(5), C(1), and D(1)-D(3).

PubMed

Morikawa, Toshio; Xie, Haihui; Wang, Tao; Matsuda, Hisashi; Yoshikawa, Masayuki

2008-10-01

From the methanolic extract of the whole plant of Sinocrassula indica (Crassulaceae), six new flavonol glycosides, sinocrassosides B(4) (1), B(5) (2), C(1) (3), D(1) (4), D(2) (5), and D(3) (6), were isolated together with 30 compounds. The structures of 1-6 were elucidated on the basis of chemical and physicochemical evidence. In addition, several constituents were found to show inhibitory effects on aminopeptidase N and aldose reductase.

A linear 180 nm SOI CMOS antenna switch module using integrated passive device filters for cellular applications

NASA Astrophysics Data System (ADS)

Jie, Cui; Lei, Chen; Peng, Zhao; Xu, Niu; Yi, Liu

2014-06-01

A broadband monolithic linear single pole, eight throw (SP8T) switch has been fabricated in 180 nm thin film silicon-on-insulator (SOI) CMOS technology with a quad-band GSM harmonic filter in integrated passive devices (IPD) technology, which is developed for cellular applications. The antenna switch module (ASM) features 1.2 dB insertion loss with filter on 2G bands and 0.4 dB insertion loss in 3G bands, less than -45 dB isolation and maximum -103 dB intermodulation distortion for mobile front ends by applying distributed architecture and adaptive supply voltage generator.

Boron neutron capture therapy demonstrated in mice bearing EMT6 tumors following selective delivery of boron by rationally designed liposomes

PubMed Central

Kueffer, Peter J.; Maitz, Charles A.; Khan, Aslam A.; Schuster, Seth A.; Shlyakhtina, Natalia I.; Jalisatgi, Satish S.; Brockman, John D.; Nigg, David W.; Hawthorne, M. Frederick

2013-01-01

The application of boron neutron capture therapy (BNCT) following liposomal delivery of a 10B-enriched polyhedral borane and a carborane against mouse mammary adenocarcinoma solid tumors was investigated. Unilamellar liposomes with a mean diameter of 134 nm or less, composed of an equimolar mixture of cholesterol and 1,2-distearoyl-sn-glycero-3-phosphocholine and incorporating Na3[1-(2′-B10H9)-2-NH3B10H8] in the aqueous interior and K[nido-7-CH3(CH2)15-7,8-C2B9H11] in the bilayer, were injected into the tail veins of female BALB/c mice bearing right flank EMT6 tumors. Biodistribution studies indicated that two identical injections given 24 h apart resulted in tumor boron levels exceeding 67 µg/g tumor at 54 h—with tumor/blood boron ratios being greatest at 96 h (5.68:1; 43 µg boron/g tumor)—following the initial injection. For BNCT experiments, tumor-bearing mice were irradiated 54 h after the initial injection for 30 min with thermal neutrons, resulting in a total fluence of 1.6 × 1012 neutrons per cm2 (±7%). Significant suppression of tumor growth was observed in mice given BNCT vs. control mice (only 424% increase in tumor volume at 14 d post irradiation vs. 1551% in untreated controls). In a separate experiment in which mice were given a second injection/irradiation treatment 7 d after the first, the tumor growth was vastly diminished (186% tumor volume increase at 14 d). A similar response was obtained for mice irradiated for 60 min (169% increase at 14 d), suggesting that neutron fluence was the limiting factor controlling BNCT efficacy in this study. PMID:23536304

Measurement of the branching ratio of B ¯ 0 → D * + τ - ν ¯ τ relative to B ¯ 0 → D * + ℓ - ν ¯ ℓ decays with a semileptonic tagging method

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sato, Y.; Iijima, T.; Adamczyk, K.

We report a measurement of the ratio R(D*) = B(more » $$\\bar{B}$$ 0→ D *+τ -$$\\bar{v}$$τ )/B($$\\bar{B}$$ 0→D *+ℓ -$$\\bar{v}$$ℓ), where ℓ denotes an electron or a muon. The results are based on a data sample containing 772 × 10 6 B$$\\bar{B}$$ pairs recorded at the (4S) resonance with the Belle detector at the KEKB e +e - collider. We select a sample of B 0 $$\\bar{B}$$ 0pairs by reconstructing both B mesons in semileptonic decays to D *∓ℓ ±. We measure R(D*) = 0.302±0.030(stat) ±0.011(syst), which is within 1.6σ of the Standard Model theoretical expectation, where the standard deviation σ includes systematic uncertainties. We use this measurement to constrain several scenarios of new physics in a model-independent approach.« less

Whistle source levels of free-ranging beluga whales in Saguenay-St. Lawrence marine park.

PubMed

Le Bot, Olivier; Simard, Yvan; Roy, Nathalie; Mars, Jérôme I; Gervaise, Cédric

2016-07-01

Wild beluga whistle source levels (SLs) are estimated from 52 three-dimensional (3D) localized calls using a 4-hydrophone array. The probability distribution functions of the root-mean-square (rms) SL in the time domain, and the peak, the strongest 3-dB, and 10-dB SLs from the spectrogram, were non-Gaussian. The average rms SL was 143.8 ± 6.7 dB re 1 μPa at 1 m. SL spectral metrics were, respectively, 145.8 ± 8 dB, 143.2 ± 7.1 dB, and 138.5 ± 6.9 dB re 1 μPa(2)·Hz(-1) at 1 m.

Molecular structure, vibrational spectroscopic analysis (IR & Raman), HOMO-LUMO and NBO analysis of anti-cancer drug sunitinib using DFT method

NASA Astrophysics Data System (ADS)

Mıhçıokur, Özlem; Özpozan, Talat

2017-12-01

Oxindole and its derivatives have wide applications in different industries such as in synthetic & natural fibers, dyes for hair and plastic materials in addition to their biological importance. In the present study, one of the oxindole derivatives, N-(2-diethylaminoethyl)-5-[(Z)-(5-fluoro-2-oxo-1H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide (Sunitinib), which is used as an anti-cancer drug, was investigated in terms of structural, vibrational spectroscopic and theoretical analysis. The calculations have been performed for gaseous, aqueous and DMSO phases, respectively. Potential Energy Surface (PES) scan has been carrried out to obtain the most stable structures of all the phases of the title molecule using B3LYP/6-31G(d,p) level and the geometrical variations among them are discussed. The solvent effect for Sunitinib in aqueous and DMSO phases have been performed by means of the self-consistent recognition reaction field (SCRF) method as implemented in the integral equation formalism polarized continuum model (IEFPCM). On the other hand, NBO analysis has been carried out to understand probable hydrogen bonding sites and charge transfers. Additionally, the HOMO and the LUMO energies are calculated using B3LYP/6-31G(d,p) to determine the intra molecular charge transfers (ICT) within the molecule and the kinetic stabilities for each phases. The molecular electrostatic potential surface (MESP) has been plotted over the optimized structure to estimate the reactive sites of electrophilic and nucleophilic attacks regarding Sunitinib molecule. The potential energy distribution (PED) has been calculated using VEDA4 program and vibrational assignments of the experimental spectra (IR & Raman) have been elucidated by means of the calculated vibrational spectra. The observed vibrational spectra of Sunitinib is compared with the calculated spectra obtained by using B3LYP functional both with 6-31G(d,p) and 6-311++G(d,p) basis sets. Theoretical results indicate that the best correlation with experimental data is obtained with B3LYP/6-311++G(d,p) method.

Nanotechnology in Aerospace Applications

DTIC Science & Technology

2007-03-01

CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING...logic and memory chips, sensors, catalyst support, adsorption media, actuators, etc. All early works in nanoelectronics use CNTs as a conducting...inspection cost effectively , quickly, and efficiently than the present procedures, composites, wear resistant tires, improved avionics, satellite

14 CFR Appendix D to Part 43 - Scope and Detail of Items (as Applicable to the Particular Aircraft) To Be Included in Annual and...

Code of Federal Regulations, 2013 CFR

2013-01-01

... internal tolerances. (4) Engine mount—for cracks, looseness of mounting, and looseness of engine to mount... aircraft and aircraft engine. (b) Each person performing an annual or 100-hour inspection shall inspect...) improper operation. (5) Flight and engine controls—for improper installation and improper operation. (6...

14 CFR Appendix D to Part 43 - Scope and Detail of Items (as Applicable to the Particular Aircraft) To Be Included in Annual and...

Code of Federal Regulations, 2014 CFR

2014-01-01

... internal tolerances. (4) Engine mount—for cracks, looseness of mounting, and looseness of engine to mount... aircraft and aircraft engine. (b) Each person performing an annual or 100-hour inspection shall inspect...) improper operation. (5) Flight and engine controls—for improper installation and improper operation. (6...

14 CFR Appendix D to Part 43 - Scope and Detail of Items (as Applicable to the Particular Aircraft) To Be Included in Annual and...

Code of Federal Regulations, 2011 CFR

2011-01-01

... internal tolerances. (4) Engine mount—for cracks, looseness of mounting, and looseness of engine to mount... aircraft and aircraft engine. (b) Each person performing an annual or 100-hour inspection shall inspect...) improper operation. (5) Flight and engine controls—for improper installation and improper operation. (6...

14 CFR Appendix D to Part 43 - Scope and Detail of Items (as Applicable to the Particular Aircraft) To Be Included in Annual and...

Code of Federal Regulations, 2012 CFR

2012-01-01

... internal tolerances. (4) Engine mount—for cracks, looseness of mounting, and looseness of engine to mount... aircraft and aircraft engine. (b) Each person performing an annual or 100-hour inspection shall inspect...) improper operation. (5) Flight and engine controls—for improper installation and improper operation. (6...

Effect of electronic ANR and conventional hearing protectors on vehicle backup alarm detection in noise.

PubMed

Casali, John G; Robinson, Gary S; Dabney, Erika Christian; Gauger, Dan

2004-01-01

An experiment was conducted wherein masked thresholds (using ascending method of limits) for a backup alarm were obtained in pink and red noise at 85 and 100 dBA for 12 participants immersed in a probability monitoring task and wearing a conventional passive hearing protection device (HPD, an earmuff or a foam earplug), an active noise reduction (ANR) headset, or no HPD at all (only in 85 dBA noise). Results revealed statistically significant between-HPD differences in red noise (from 2.3 to 3.1 dB) and in the 100-dBA noise level (from 2.6 to 4.3 dB). An additional finding, which corroborates other studies using different protocols, was that masked thresholds in 85-dBA noise were significantly lower (from 3.2 to 4.4 dB) for the occluded conditions (wearing an HPD) than for the open-ear (unoccluded) condition. This result refutes the belief among many normal-hearing workers that the use of HPDs in relatively low levels of noise compromises their ability to hear necessary workplace sounds. Actual or potential applications of this research include (a) the selection of appropriate HPDs for low-frequency-biased noise exposures wherein signal detection is important and (b) gaining insight into the appropriateness of ANR-based HPDs for certain industrial noise environments.

Condition Based Maintenance Technology Impacts Study for the Military Land Environment

DTIC Science & Technology

2014-08-01

3a, 2g 3b,3m,3j,3e,3d,3f,3a,3c,3i 3c,3d,3h,3n 3d,3h 3e,3k,3i 3f,3h UNCLASSIFIED DSTO-RR-0404 UNCLASSIFIED 158 3g ,3c 3h,4b 3i,3m,3j,CBM...3e -> 3k 3i Egress of 2: 3n -> 3h 4b Egress of 2: 3k -> 3j 5c Egress of 2: 4d -> 3g 3c Egress of 1: 3a -> 2g Egress of 1: 1b -> 2g Egress...Ingress+Egress of 8: 2d 3b 3g 4d 4f -> 3c -> 3d 3h 3n Ingress+Egress of 7: 1b 2e 3a -> 2g -> 3b 2e 2c 2f Ingress+Egress of 7: 2a 2d 6b 6c -> 2b -> 3a

Human Health Countermeasures (HHC) Element Management Plan: Human Research Program. Revision B

NASA Technical Reports Server (NTRS)

Norsk, Peter; Baumann, David

2012-01-01

NASA s Human Research Program (HRP) is an applied research and technology program within the Human Exploration and Operations Mission Directorate (HEOMD) that addresses human health and performance risk mitigation strategies in support of exploration missions. The HRP research and technology development is focused on the highest priority risks to crew health and safety with the goal of ensuring mission success and maintaining long-term crew health. Crew health and performance standards, defined by the NASA Chief Health and Medical Officer (CHMO), set the acceptable risk level for exploration missions. The HRP conducts research to inform these standards as well as provide deliverables, such as countermeasures, that ensure standards can be met to maximize human performance and mission success. The Human Health Countermeasures (HHC) Element was formed as part of the HRP to develop a scientifically-based, integrated approach to understanding and mitigating the health risks associated with human spaceflight. These health risks have been organized into four research portfolios that group similar or related risks. A fifth portfolio exists for managing technology developments and infrastructure projects. The HHC Element portfolios consist of: a) Vision and Cardiovascular; b) Exercise and Performance; c) Multisystem; d) Bone; and e) Technology and Infrastructure. The HHC identifies gaps associated with the health risks and plans human physiology research that will result in knowledge required to more fully understand risks and will result in validated countermeasures to mitigate risks.

75 FR 24936 - Columbia Gas Transmission, LLC, and D&B Resources; Notice of Application

Federal Register 2010, 2011, 2012, 2013, 2014

2010-05-06

... Resources (D&B), Rt. 4 Box 232, Cameron, West Virginia 26033, filed with the Commission a joint application... Transmission, LLC, P.O. Box 1273, Charleston, West Virginia 25325; telephone (304) 357-2359, fax (304) 357-3206...

Metasurface Reflector (MSR) Loading for High Performance Small Microstrip Antenna Design

PubMed Central

Ahsan, Md Rezwanul; Islam, Mohammad Tariqul; Ullah, Mohammad Habib; Singh, Mandeep Jit; Ali, Mohd Tarmizi

2015-01-01

A meander stripline feed multiband microstrip antenna loaded with metasurface reflector (MSR) structure has been designed, analyzed and constructed that offers the wireless communication services for UHF/microwave RFID and WLAN/WiMAX applications. The proposed MSR assimilated antenna comprises planar straight forward design of circular shaped radiator with horizontal slots on it and 2D metasurface formed by the periodic square metallic element that resembles the behavior of metamaterials. A custom made high dielectric bio-plastic substrate (ε r = 15) is used for fabricating the prototype of the MSR embedded planar monopole antenna. The details of the design progress through numerical simulations and experimental results are presented and discussed accordingly. The measured impedance bandwidth, radiation patterns and gain of the proposed MSR integrated antenna are compared with the obtained results from numerical simulation, and a good compliance can be observed between them. The investigation shows that utilization of MSR structure has significantly broadened the -10dB impedance bandwidth than the conventional patch antenna: from 540 to 632 MHz (17%), 467 to 606 MHz (29%) and 758 MHz to 1062 MHz (40%) for three distinct operating bands centered at 0.9, 3.5 and 5.5 GHz. Additionally, due to the assimilation of MSR, the overall realized gains have been upgraded to a higher value of 3.62 dBi, 6.09 dBi and 8.6 dBi for lower, middle and upper frequency band respectively. The measured radiation patterns, impedance bandwidths (S11<-10 dB) and gains from the MSR loaded antenna prototype exhibit reasonable characteristics that can satisfy the requirements of UHF/microwave (5.8 GHz) RFID, WiMAX (3.5/5.5 GHz) and WLAN (5.2/5.8 GHz) applications. PMID:26018795

Metasurface Reflector (MSR) Loading for High Performance Small Microstrip Antenna Design.

PubMed

Ahsan, Md Rezwanul; Islam, Mohammad Tariqul; Ullah, Mohammad Habib; Singh, Mandeep Jit; Ali, Mohd Tarmizi

2015-01-01

A meander stripline feed multiband microstrip antenna loaded with metasurface reflector (MSR) structure has been designed, analyzed and constructed that offers the wireless communication services for UHF/microwave RFID and WLAN/WiMAX applications. The proposed MSR assimilated antenna comprises planar straight forward design of circular shaped radiator with horizontal slots on it and 2D metasurface formed by the periodic square metallic element that resembles the behavior of metamaterials. A custom made high dielectric bio-plastic substrate (εr = 15) is used for fabricating the prototype of the MSR embedded planar monopole antenna. The details of the design progress through numerical simulations and experimental results are presented and discussed accordingly. The measured impedance bandwidth, radiation patterns and gain of the proposed MSR integrated antenna are compared with the obtained results from numerical simulation, and a good compliance can be observed between them. The investigation shows that utilization of MSR structure has significantly broadened the -10 dB impedance bandwidth than the conventional patch antenna: from 540 to 632 MHz (17%), 467 to 606 MHz (29%) and 758 MHz to 1062 MHz (40%) for three distinct operating bands centered at 0.9, 3.5 and 5.5 GHz. Additionally, due to the assimilation of MSR, the overall realized gains have been upgraded to a higher value of 3.62 dBi, 6.09 dBi and 8.6 dBi for lower, middle and upper frequency band respectively. The measured radiation patterns, impedance bandwidths (S11<-10 dB) and gains from the MSR loaded antenna prototype exhibit reasonable characteristics that can satisfy the requirements of UHF/microwave (5.8 GHz) RFID, WiMAX (3.5/5.5 GHz) and WLAN (5.2/5.8 GHz) applications.

Electrocoagulation improving bone cement use in middle-ear surgery: short-term and middle-term results.

PubMed

Galy-Bernadoy, C; Akkari, M; Mondain, M; Uziel, A; Venail, F

2016-12-01

Bone cement is used for ossicular chain repair and revision stapes surgery. Its efficient use requires cautious removal of mucosa from the ossicles. This paper reports a technique for easy, fast and safe removal of this mucosa prior to cement application. It consists of the application of monopolar electrocoagulation on the ossicles prior to bone cement application. The outcomes of six cases of revision stapes surgery and seven cases of partial ossiculoplasty, conducted between 2007 and 2012 using this new technique, were evaluated. Intra-operative reports and audiometric data were collected. During the last assessment, reconstruction using bone cement resulted in mean post-operative air-bone gaps of 4.1 ± 6.5 dB in revision stapes surgery cases and 5.7 ± 5.5 dB in partial ossiculoplasty cases, reflecting a significant hearing improvement (p = 0.03). No complications were observed. Electrocoagulation allows the removal of mucosa from the ossicles in an easy, fast and safe manner, enabling the use of bone cement for ossicular chain reconstruction.

Printed 2 V-operating organic inverter arrays employing a small-molecule/polymer blend.

PubMed

Shiwaku, Rei; Takeda, Yasunori; Fukuda, Takashi; Fukuda, Kenjiro; Matsui, Hiroyuki; Kumaki, Daisuke; Tokito, Shizuo

2016-10-04

Printed organic thin-film transistors (OTFTs) are well suited for low-cost electronic applications, such as radio frequency identification (RFID) tags and sensors. Achieving both high carrier mobility and uniform electrical characteristics in printed OTFT devices is essential in these applications. Here, we report on printed high-performance OTFTs and circuits using silver nanoparticle inks for the source/drain electrodes and a blend of dithieno[2,3-d;2',3'-d']benzo[1,2-b;4,5-b']dithiophene (DTBDT-C 6 ) and polystyrene for the organic semiconducting layer. A high saturation region mobility of 1.0 cm 2  V -1  s -1 at low operation voltage of -5 V was obtained for relatively short channel lengths of 9 μm. All fifteen of the printed pseudo-CMOS inverter circuits were formed on a common substrate and operated at low operation voltage of 2 V with the total variation in threshold voltage of 0.35 V. Consequently, the printed OTFT devices can be used in more complex integrated circuit applications requiring low manufacturing cost over large areas.

Distribution of HLA-B27 and CYP2D6*4 mutations in the middle Black Sea area (Tokat) of Turkey.

PubMed

Sahin, S; Aydogan, L; Benli, I; Ozyurt, H

2011-12-02

We analyzed distribution of HLA-B27 and CYP2D6*4 mutations in 249 patients from Tokat province in Turkey with symptoms of arthritis, sacroiliac, joint and back pain, using a LightCycler 480 II Real-Time PCR thermal cycler. The Genes-4U was applied for studying HLA-B27 mutation, and the Tib-Molbiol commercial kit was used to examine the CYP2D6*4 mutation. Among the 249 patients, 18.5% had the HLA-B27 mutation. The CYP2D6*4 mutation was found in 22.0% (six homozygotes). Ten patients had both mutations. These frequencies are similar to what has been reported from other populations.

Design and characterisation of miniaturised cavity-backed patch antenna for microwave hyperthermia.

PubMed

Chakaravarthi, Geetha; Arunachalam, Kavitha

2015-01-01

The aim of this study was to describe the design and characterisation of a miniaturised 434 MHz patch antenna enclosed in a metal cavity for microwave hyperthermia treatment of cancer. Electromagnetic (EM) field distribution in the near field of a microstrip patch irradiating body tissue was studied using finite element method (FEM) simulations. Antenna miniaturisation was achieved through dielectric loading with very high permittivity, metal enclosure, patch folding and shorting post. Frequency dependent electrical properties of materials were incorporated wherever appropriate using dispersion model and measurements. Antenna return loss and specific absorption rate (SAR) at 434 MHz were measured on muscle phantoms for characterisation. The design was progressively optimised to yield a compact 434 MHz patch (22 mm × 8.8 mm × 10 mm) inside a metal cavity (40 mm × 12 mm) with integrated coupling water bolus (35 mm). The fabricated antenna with integrated water bolus was self resonant at 434 MHz without load, and has better than -10 dB return loss (S11) with 13-20 MHz bandwidth on two different phantoms. SAR at 434 MHz measured using an infrared (IR) thermal camera on split phantoms indicated penetration depth for -3 dB SAR as 8.25 mm compared to 8.87 mm for simulation. The simulated and measured SAR coverage along phantom depth was 3.09 cm(2) and 3.21 cm(2) respectively at -3 dB, and 6.42 cm(2) and 9.07 cm(2) respectively at -6 dB. SAR full width at half maximum (FWHM) at 5 mm and 20 mm depths were 54.68 mm and 51.18 mm respectively in simulation, and 49.47 mm and 43.75 mm respectively in experiments. Performance comparison of the cavity-backed patch indicates more than 89% co-polarisation and higher directivity which resulted in deeper penetration compared to the patch applicators of similar or larger size proposed for hyperthermia treatment of cancer. The fabricated cavity-backed applicator is self-resonant at 434 MHz with a negligible shift in resonance when coupled to different phantoms, Δf/f0 less than 1.16%. IR thermography-based SAR measurements indicated that the -3 dB SAR of the cavity-backed aperture antenna covered the radiating aperture surface at 5 mm and 20 mm depths. It can be concluded that the compact cavity-backed patch antenna has stable resonance, higher directivity and low cross polarisation, and is suitable for design of microwave hyperthermia array applicators with adjustable heating pattern for superficial and/or deep tissue heating.

Observation of B^{0}→pΛ[over ¯]D^{(*)-}.

PubMed

Chang, Y-Y; Wang, M-Z; Abdesselam, A; Adachi, I; Adamczyk, K; Aihara, H; Al Said, S; Asner, D M; Atmacan, H; Aushev, T; Babu, V; Badhrees, I; Bakich, A M; Barberio, E; Bhuyan, B; Biswal, J; Bobrov, A; Bozek, A; Bračko, M; Browder, T E; Červenkov, D; Chekelian, V; Chen, A; Cheon, B G; Chilikin, K; Chistov, R; Chobanova, V; Choi, S-K; Choi, Y; Cinabro, D; Dalseno, J; Danilov, M; Dingfelder, J; Doležal, Z; Drásal, Z; Dutta, D; Eidelman, S; Farhat, H; Fast, J E; Ferber, T; Fulsom, B G; Gaur, V; Gabyshev, N; Ganguly, S; Garmash, A; Gillard, R; Glattauer, R; Goh, Y M; Goldenzweig, P; Greenwald, D; Grzymkowska, O; Haba, J; Hayasaka, K; Hayashii, H; He, X H; Hou, W-S; Hsu, C-L; Iijima, T; Inami, K; Ishikawa, A; Itoh, R; Iwasaki, Y; Jacobs, W W; Jaegle, I; Joffe, D; Joo, K K; Kawasaki, T; Kim, D Y; Kim, H J; Kim, J B; Kim, J H; Kim, K T; Kim, M J; Kim, S H; Kim, Y J; Kinoshita, K; Korpar, S; Križan, P; Krokovny, P; Kuhr, T; Kumita, T; Kuzmin, A; Kwon, Y-J; Lai, Y-T; Lee, I S; Li, L; Li, Y; Libby, J; Liventsev, D; Lukin, P; Masuda, M; Matvienko, D; Miyabayashi, K; Miyake, H; Miyata, H; Mizuk, R; Mohanty, G B; Mohanty, S; Moll, A; Moon, H K; Mori, T; Nakano, E; Nakao, M; Nanut, T; Nayak, M; Nishida, S; Ogawa, S; Ozaki, H; Pakhlov, P; Pakhlova, G; Pal, B; Park, C W; Pedlar, T K; Pestotnik, R; Petrič, M; Piilonen, L E; Rauch, J; Ribežl, E; Ritter, M; Rostomyan, A; Ryu, S; Sahoo, H; Sakai, Y; Sandilya, S; Santelj, L; Sanuki, T; Savinov, V; Schneider, O; Schnell, G; Schwanda, C; Seino, Y; Senyo, K; Seong, I S; Sevior, M E; Shebalin, V; Shen, C P; Shibata, T-A; Shiu, J-G; Simon, F; Sohn, Y-S; Starič, M; Stypula, J; Sumihama, M; Sumisawa, K; Sumiyoshi, T; Tamponi, U; Tanida, K; Teramoto, Y; Uglov, T; Unno, Y; Uno, S; Usov, Y; Van Hulse, C; Vanhoefer, P; Varner, G; Vorobyev, V; Vossen, A; Wagner, M N; Wang, C H; Wang, P; Watanabe, M; Watanabe, Y; Williams, K M; Won, E; Yamaoka, J; Yashchenko, S; Yelton, J; Yusa, Y; Zhang, Z P; Zhilich, V; Zhulanov, V; Zupanc, A

2015-11-27

We report the first observation of the decays B^{0}→pΛ[over ¯]D^{(*)-}. The data sample of 711  fb^{-1} used in this analysis corresponds to 772×10^{6} BB[over ¯] pairs, collected at the ϒ(4S) resonance by the Belle detector at the KEKB asymmetric-energy e^{+}e^{-} collider. We observe 19.8σ and 10.8σ excesses of events for the two decay modes and measure the branching fractions of B^{0}→pΛ[over ¯]D^{-} and B^{0}→pΛ[over ¯]D^{*-} to be (25.1±2.6±3.5)×10^{-6} and (33.6±6.3±4.4)×10^{-6}, respectively, where the first uncertainties are statistical and the second are systematic. These results are not compatible with the predictions based on the generalized factorization approach. In addition, a threshold enhancement in the dibaryon (pΛ[over ¯]) system is observed, consistent with that observed in similar B decays.

Secretory expression of a heterologous protein, Aiio-AIO6BS, in Bacillus subtilis via a non-classical secretion pathway.

PubMed

Pan, Xingliang; Yang, Yalin; Liu, Xuewei; Li, Dong; Li, Juan; Guo, Xiaoze; Zhou, Zhigang

2016-09-16

The quenching enzyme AIO6 (AiiO-AIO6) has been reported as a feed additive preparation for application in aquaculture and biological control of pathogenic Aeromonas hydrophila. We developed an economical strategy to express AIO6BS (AiiO-AIO6BS, codon optimized AIO6 in Bacillus subtilis) in Bacillus subtilis for facilitating its widespread application. Promoter p43 without the signal peptide was used for secretory expression of AIO6BS in B. subtilis. Western blotting analysis demonstrated that AIO6BS was successfully expressed and secreted into the cell culture. Expression analysis of AIO6BS in the single or double mutant of the lytC and lytD genes for cell autolysis in B. subtilis 1A751 and cell autolysis-resistant engineered strain LM2531 derived from the wild type 168 indicated that the release of the heterologous protein AIO6BS was not simply mediated by cell lysis. Expression level of AIO6BS did not change in the mutants of B. subtilis that harbored mutations in the secA, tatAC, or ecsA genes compared with that in the parent wild type strain. These results suggested the AIO6BS protein was likely secreted via a non-classical secretion pathway. The expression analysis of the various N- or C-terminal truncated gene products indicated that AIO6BS probably acts as an export signal to direct its self-secretion across the cell membrane. Copyright © 2016 Elsevier Inc. All rights reserved.

A new coherent demodulation technique for land-mobile satellite communications

NASA Technical Reports Server (NTRS)

Yoshida, Shousei; Tomita, Hideho

1990-01-01

An advanced coherent demodulation technique is described for land mobile satellite (LMS) communications. The proposed technique features a combined narrow/wind band dual open loop carrier phase estimator, which is effectively able to compensate the fast carrier phase fluctuation by fading with sacrificing a phase slip rate. Also included is the realization of quick carrier and clock reacquisition after shadowing by taking open loop structure. Its bit error rate (BER) performance is superior to that of existing detection schemes, showing a BER of 1 x 10(exp -2) at 6.3 dB E sub b/N sub o over the Rician channel with 10 dB C/M and 200 Hz (1/16 modulation rate) fading pitch f sub d for QPSK. The proposed scheme consists of a fast response carrier recovery and a quick bit timing recovery with an interpolation. An experimental terminal model was developed to evaluate its performance at fading conditions. The results are quite satisfactory, giving prospects for future LMS applications.

The influence of temperature on the work function of W, LaB 6 and pseudo-alloys

NASA Astrophysics Data System (ADS)

Bulyga, A. V.; Solonovich, V. K.

1989-12-01

The experimental temperature dependences α f = d F/d T of the work function F = F( T) for W(111), LaB 6(100) and W-Ni-LaB 6 pseudo-alloy surfaces emitting thermoelectrons are compared with α f predicted by the Hohenberg-Lang-Kohn theory.

47 CFR 80.205 - Bandwidths.

Code of Federal Regulations, 2010 CFR

2010-10-01

... frequency deviation for F3E or G3E emission is as follows: (1) 5 kHz in the 72.0-73.0 MHz, 75.4-76.0 MHz and... 12 16K0A2D 20.0 A3E 6K00A3E 8.0 A3N 2 2K66A3N 2.8 A3X 3 3K20A3X 25.0 F1B 4 280HF1B 0.3 F1B 5 300HF1B 0.5 F1B 6 16KOF1B 20.0 F1C 2K80F1C 3.0 F1D 12 16K0F1D 20.0 F2B 6 16KOF2B 20.0 F2C 7 16KOF2C 20.0 F2D...

Paperless Transaction for Publication Incentive System

NASA Astrophysics Data System (ADS)

Ibrahim, Rosziati; Madon, Hamiza Diana; Nazri, Nurul Hashida Amira Mohd; Saarani, Norhafizah; Mustapha, Aida

2017-08-01

Within the Malaysian context, incentive system in scientific publishing rewards authors for publishing journal articles or conference papers that are indexed by Scopus. At Universiti Tun Hussein Onn Malaysia, the incentive system is going into its third year in operational. The main challenge lies in preparing the evidences as required by the application guideline. This paper presents an online module for publication incentive within the University Publication Information System (SMPU). The module was developed using the Scrum methodology based on the existing workflow of paper-based application. The module is hoped to increase the quality of the system deliverables of SMPU as well as having the ability to cope with change of university requirements in the future.

Linking secondary school physical education with community sport and recreation for girls: a process evaluation.

PubMed

Casey, Meghan M; Telford, Amanda; Mooney, Amanda; Harvey, Jack T; Eime, Rochelle M; Payne, Warren R

2014-10-06

The purpose of this study was to undertake a process evaluation to examine the reach, adoption and implementation of a school-community linked physical activity (PA) program for girls aged 12 - 15 years (School Years 7 - 9) using the RE-AIM framework. Various approaches were used to assess 'reach', 'adoption' and implementation: (a) a school environment survey of intervention schools (n = 6); (b) teacher feedback regarding the professional development component (91.1% response rate) and lesson implementation (60.8% response rate); and (c) post-intervention focus group interviews with physical education (PE) teachers (n = 29), students (n = 125), coaches (n = 13) and instructors (n = 8) regarding program experiences. Reach and Adoption: Seven schools (n = 1491 Year 7-9 female student enrolment; 70% adoption rate), five tennis clubs, eight football clubs and five leisure centres participated in the program during 2011. Program design and professional development opportunities (training, resource manual and opportunities to work with coaches and instructors during PE classes) supported implementation and student engagement in PA. However, there was a lack of individual and organisational readiness to adopt program principles. For some deliverers there were deeply embedded ideologies that were not aligned with the Game Sense teaching approach upon which the program was based. Further, cognitive components of the program such as self-management were not widely adopted as other components of the program tended to be prioritised. The program design and resources supported the success of the program, however, some aspects were not implemented as intended, which may have affected the likelihood of achieving further positive outcomes. Barriers to program implementation were identified and should be considered when designing school-community linked interventions. In particular, future programs should seek to assess and adjust for organizational readiness within the study design. For example, shared commitment and abilities of program deliverers to implement the program needs to be determined to support program implementation. ACTRN12614000446662. April 30th 2014.

Mechanics Methodology for Textile Preform Composite Materials

NASA Technical Reports Server (NTRS)

Poe, Clarence C., Jr.

1996-01-01

NASA and its contractors have completed a program to develop a basic mechanics underpinning for textile composites. Three major deliverables were produced by the program: 1. A set of test methods for measuring material properties and design allowables; 2. Mechanics models to predict the effects of the fiber preform architecture and constituent properties on engineering moduli, strength, damage resistance, and fatigue life; and 3. An electronic data base of coupon type test data. This report describes these three deliverables.

Size Effects in Linear Elastic Fracture Mechanics

DTIC Science & Technology

1988-01-01

Fracture, Brighton, U.K., (1969) 119-130. 65 D. H. Winne and B. M. Wundt , "Application of the Griffith-Irwin Theory of Crack Propagation to the Bursting...1.10 d 1.0 1.00 d 2.0 0.82 b-d Winne and Wundt [65], 1.32 1.52 0.88 b-d Ni-Mo-V, RDS 4.56 0.64 b Ni-Mo-V (0.27 Mo), RDS 1.32 4.56 0.71 d 2.66 0.81 d Cr

Marginal Vitamin B-6 Deficiency Decreases Plasma (n-3) and (n-6) PUFA Concentrations in Healthy Men and Women123

PubMed Central

Zhao, Mei; Lamers, Yvonne; Ralat, Maria A.; Coats, Bonnie S.; Chi, Yueh-Yun; Muller, Keith E.; Bain, James R.; Shankar, Meena N.; Newgard, Christopher B.; Stacpoole, Peter W.; Gregory, Jesse F.

2012-01-01

Previous animal studies showed that severe vitamin B-6 deficiency altered fatty acid profiles of tissue lipids, often with an increase of linoleic acid and a decrease of arachidonic acid. However, little is known about the extent to which vitamin B-6 deficiency affects human fatty acid profiles. The aim of this study was to determine the effects of marginal vitamin B-6 deficiency on fatty acid profiles in plasma, erythrocytes, and peripheral blood mononuclear cells (PBMC) of healthy adults fed a 28-d, low-vitamin B-6 diet. Healthy participants (n = 23) received a 2-d, controlled, vitamin B-6–adequate diet followed by a 28-d, vitamin B-6–restricted diet to induce a marginal deficiency. Plasma HDL and LDL cholesterol concentrations, FFA concentrations, and erythrocyte and PBMC membrane fatty acid compositions did not significantly change from baseline after the 28-d restriction. Plasma total arachidonic acid, EPA, and DHA concentrations decreased from (mean ± SD) 548 ± 96 to 490 ± 94 μmol/L, 37 ± 13 to 32 ± 13 μmol/L, and 121 ± 28 to 109 ± 28 μmol/L [positive false discovery rate (pFDR) adjusted P < 0.05], respectively. The total (n-6):(n-3) PUFA ratio in plasma exhibited a minor increase from 15.4 ± 2.8 to 16.6 ± 3.1 (pFDR adjusted P < 0.05). These data indicate that short-term vitamin B-6 restriction decreases plasma (n-3) and (n-6) PUFA concentrations and tends to increase the plasma (n-6):(n-3) PUFA ratio. Such changes in blood lipids may be associated with the elevated risk of cardiovascular disease in vitamin B-6 insufficiency. PMID:22955512

CMOS Life Suitability Evaluation Program

DTIC Science & Technology

1979-10-01

A B 7845 1990 118 29.9 253.6 251.3 C 1910 28.7 251.6 o 125 A 01 0.00 125.0 B 0.2 0.00 125.0 225 A 6 124 169 1.86 2.54 225.6 225.8...T a«. ^■■—. ^a^^^mmmm (1) (2) (6) (7) (11) urn uiii »nu II-S» "Q" CLOCK (14) CLOCK ENABLE (13) RESET Ch (15) ^ •rMXD...8217S- ro Ch 8 CM CM «3- LI F E R DA S IZ 00 o d d d d d d o d d d d VO d ro X UJ O _i 0 O Q. z < o r") uo i^ o o o o CM ro o