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Sample records for denmark bedre integration

  1. Denmark.

    PubMed

    1988-11-01

    Denmark is predominantly a low, flat land with such resources as oil, gas and arable land. The Danish are comprised of Scandinavian, Eskimo, Faroese and German peoples, and the languages spoken include Danish, Farese, Greenlandic and some German. The Danish enjoy a literacy rate of nearly 100%, and school attendance is 100%. The Danes are a homogeneous Gothic-Germanic people who have lived in Denmark since the prehistoric period. The Evangelical Lutheran Church is supported by 97% of the population; however, other religions are present. The government of Denmark is a constitutional monarchy with an executive, legislative and judicial branch. The political life is democratic, and compromise is a very important component of the political life of Denmark as many parties and factions must work together. Support for cultural growth comes from the Ministry of Cultural Affairs which subsidizes projects, training other cultural activities. The infant mortality rate is 8.2/1000. Life expectancy for men is 71.5 and for women 77.5.

  2. Integrated hydrological SVAT model for climate change studies in Denmark

    NASA Astrophysics Data System (ADS)

    Mollerup, M.; Refsgaard, J.; Sonnenborg, T. O.

    2010-12-01

    In a major Danish funded research project (www.hyacints.dk) a coupling is being established between the HIRHAM regional climate model code from Danish Meteorological Institute and the MIKE SHE distributed hydrological model code from DHI. The linkage between those two codes is a soil vegetation atmosphere transfer scheme, which is a module of MIKE SHE. The coupled model will be established for the entire country of Denmark (43,000 km2 land area) where a MIKE SHE based hydrological model already exists (Henriksen et al., 2003, 2008). The present paper presents the MIKE SHE SVAT module and the methodology used for parameterising and calibrating the MIKE SHE SVAT module for use throughout the country. As SVAT models previously typically have been tested for research field sites with comprehensive data on energy fluxes, soil and vegetation data, the major challenge lies in parameterisation of the model when only ordinary data exist. For this purpose annual variations of vegetation characteristics (Leaf Area Index (LAI), Crop height, Root depth and the surface albedo) for different combinations of soil profiles and vegetation types have been simulated by use of the soil plant atmosphere model Daisy (Hansen et al., 1990; Abrahamsen and Hansen, 2000) has been applied. The MIKE SHE SVAT using Daisy generated surface/soil properties model has been calibrated against existing data on groundwater heads and river discharges. Simulation results in form of evapotranspiration and percolation are compared to the existing MIKE SHE model and to observations. To analyse the use of the SVAT model in climate change impact assessments data from the ENSEMBLES project (http://ensembles-eu.metoffice.com/) have been analysed to assess the impacts on reference evapotranspiration (calculated by the Makkink and the Penmann-Monteith equations) as well as on the individual elements in the Penmann-Monteith equation (radiation, wind speed, humidity and temperature). The differences on the

  3. High-Resolution Modelling of Health Impacts from Air Pollution for Denmark using the Integrated Model System EVA

    NASA Astrophysics Data System (ADS)

    Brandt, Jørgen; Andersen, Mikael S.; Bønløkke, Jakob; Christensen, Jesper H.; Hansen, Kaj M.; Hertel, Ole; Im, Ulas; Jensen, Steen S.; Ketzel, Matthias; Nielsen, Ole-Kenneth; Plejdrup, Marlene S.; Sigsgaard, Torben; Geels, Camilla

    2015-04-01

    We have developed an integrated health impact assessment system EVA (Economic Valuation of Air pollution; Brandt et al., 2013a; 2013b), based on the impact-pathway chain, to assess the health impacts and health-related economic externalities of air pollution resulting from specific emission sources or sectors. The system is used to support policymaking with respect to emission control. The EVA system has previously been used to assess the health impacts based on results from a regional model DEHM (the Danish Eulerian Hemispheric Model; Brandt et al., 2012). In this study we have used a coupling of two chemistry transport models to calculate the air pollution concentration at different scales; the DEHM model to calculate the air pollution levels with a resolution down to 5.6 km x 5.6 km and the UBM model (Urban Background Model ; Berkowicz, 2000; Brandt et al., 2001) to further calculate the air pollution at 1 km x 1 km resolution for Denmark using results from DEHM as boundary conditions. Both the emission data based on the SPREAD model (Plejdrup and Gyldenkærne, 2011) as well as the population density has been represented in the model system with the same high resolution. The new developments of the integrated model system will be presented as well as results for health impacts and related external costs over the years 2006-2014 for Denmark. Furthermore, a sensitivity study of the health impact using coarse and fine resolutions in the model system has been carried out to evaluate the effect of improved description of the geographical population distribution with respect to location of local emissions. References Berkowicz, R., 2000. A Simple Model for Urban Background Pollution. Environmental Monitoring and Assessment, 65, 1/2, 259-267. Brandt, J., J. H. Christensen, L. M. Frohn, F. Palmgren, R. Berkowicz and Z. Zlatev, 2001: "Operational air pollution forecasts from European to local scale". Atmospheric Environment, Vol. 35, Sup. No. 1, pp. S91-S98, 2001 Brandt

  4. Integrated trend assessment of ecosystem changes in the Limfjord (Denmark): Evidence of a recent regime shift?

    NASA Astrophysics Data System (ADS)

    Tomczak, Maciej T.; Dinesen, Grete E.; Hoffmann, Erik; Maar, Marie; Støttrup, Josianne G.

    2013-01-01

    An integrated ecosystem assessment was carried out for the Limfjord over the period from 1984 to 2008 to describe changes in ecosystem structure and potentially important drivers. The Limfjord is a eutrophic transitional Danish fjord system with the main inflow from the North Sea in the west and main outflow to the Kattegat in the east. We showed that from 1990 to 1995, the ecosystem structure shifted from dominance by demersal fish species (eelpout, whiting, flounder, plaice) to that of pelagic fish species (sprat, herring, sticklebacks), small-bodied fish species (black goby, pipefish), jellyfish, common shore crab, starfish and blue mussels. We interpret this change as a regime shift that showed a similar temporal pattern to regime shifts identified in adjacent seas. The observed changes in trophic interactions and food web reorganisation suggested a non-linear regime shift. The analyses further showed the regime shift to be driven by a combination of anthropogenic pressures and possible interplay with climatic disturbance.

  5. Determination of petrophysical properties of geothermal reservoirs in southern Denmark by integrating information from well logs and reflection seismic data

    NASA Astrophysics Data System (ADS)

    Rasmussen, Marie L.; Balling, Niels; Bording, Thue S.; Clausen, Ole R.

    2013-04-01

    As part of the efforts to reduce CO2 emission, geothermal energy is an important source for future energy production in Denmark, and several research programs deal with this specific subject e.g. "The geothermal energy potential in Denmark - reservoir properties, temperature distribution and models for utilization", funded by the Danish Strategic Research Council and "GEOPOWER" which is part of an EU INTERREG-program focused on southern Denmark and northernmost Germany. For geothermal energy to be economically sustainable porous and permeable rocks needs to be present at a depth where the temperature is sufficiently high. Utilization of geothermal energy in Denmark and plans for the future are concentrated on low enthalpy basin reservoirs for district heating. Major modeling studies are carried out to establish the temperature distribution in the Danish subsurface. This project deals with the reservoir properties. The geothermal reservoir exploited so far in the southern Danish area is restricted to the lower Jurassic-Triassic Gassum Formation. The Gassum Formation is a shallow marine to fluvial deposit composed of sandy to silty sediments, occasionally with coal layers, i.e. a lateral and stratigraphically heterogeneous rock. This formation is encountered only in deep hydrocarbon exploration wells and in wells of the Sønderborg Geothermal plant. Due to the very low number and low density of wells and the limited rock material recovered during drilling, the knowledge of lateral variations of reservoir properties in terms of porosity, permeability and thickness, is limited and so far unsatisfactorily mapped. The main risks in the utilization of geothermal energy from the subsurface of Denmark are therefore regional, as well as local, variations in the production potential of warm water, whereas the temperature can be assessed fairly precisely due to the thermal models available. Here we use petrophysical wells logs available from hydrocarbon exploration wells for

  6. The Way We Think: A Research Symposium on Conceptual Integration and the Nature and Origin of Cognitively Modern Human Beings (Odense, Denmark, August 19-23, 2002). Volumes I [and] II.

    ERIC Educational Resources Information Center

    Hougaard, Anders, Ed.; Lund, Steffen Nordahl, Ed.

    2002-01-01

    These 2 volumes include papers and abstracts of papers presented at the August 2002 "The Way We Think" conference in Denmark. Papers and abstracts of papers in the two volumes include: "Blending and Conceptual Disintegration" (Anders Hougaard); "Levels of Blending, Disintegration, and Language Evolution" (Carl Bache); "Conceptual Integration,…

  7. What's Happening in Denmark?

    ERIC Educational Resources Information Center

    Morris, Corey

    2012-01-01

    This article describes the author's experience in alumni relations in a country, Denmark, where few are willing to bear the institution's logo. The author likens his journey to that of Lewis and Clark, who introduced the rest of America to the western part of North America. And just like them, the author and his colleague experienced unforeseen…

  8. Denmark. [CME Country Reports].

    ERIC Educational Resources Information Center

    Council of Europe, Strasbourg (France). Documentation Center for Education in Europe.

    According to an agreement between the parties of the labour market and the Ministry of Labour, the immigration of foreign workers into Denmark takes place on a quota basis and conforms to a series of regulations, including a rule that the foreign worker, prior to departing from his country, must have made contract arrangements for his job. This…

  9. Spotlight on VET Denmark

    ERIC Educational Resources Information Center

    Cedefop - European Centre for the Development of Vocational Training, 2012

    2012-01-01

    This paper presents data on the vocational education and training (VET) in Denmark. VET plays a key role in the Danish strategy for lifelong learning and meeting the challenges of globalisation and technological change. The Danish education and training system comprises a mainstream system providing qualifications at all levels, from compulsory…

  10. Educational Governance in Denmark

    ERIC Educational Resources Information Center

    Moos, Lejf

    2014-01-01

    Denmark has entered global competition by expanding collaboration with European countries, which is profoundly impacting the public sector and school governance. Relations between the state and institutions are transforming from traditional democratic, public-sector models of governance into new forms characterized as corporate and market-driven…

  11. Vocational Training in Denmark.

    ERIC Educational Resources Information Center

    Rasmussen, Werner

    Denmark has a wide range of basic vocational training courses that can be begun immediately after completion of lower secondary school, i.e., after students complete their compulsory education at the age of 15 or 16). This is not to say that there is no vocational education at the primary and secondary levels, where guest teachers from working…

  12. Virtual Reality in Denmark

    DTIC Science & Technology

    2005-12-01

    technologies are available in CAVI: VIRTUAL REALITY IN DENMARK 2 - 2 RTO-TR-HFM-121-Part-I • 3D Panorama Cinema Curved screen Active stereo...glasses Tracking Figure 3: 3D Panorama Cinema at CAVI. • The Panorama cinema is a cylinder shaped screen placed in a room that seats approximately...15-20 persons. The size and shape of the screen mean that the visual angle of the spectators is almost covered by the screen . Models are displayed

  13. The Way We Think: A Research Symposium on Conceptual Integration and the Nature and Origin of Cognitively Modern Human Beings (Odense, Denmark, August 19-23, 2002).

    ERIC Educational Resources Information Center

    Hougaard, Anders, Ed.; Lund, Steffen Nordahl, Ed.

    2002-01-01

    This collection of conference papers and abstracts includes: "Integrating Two Languages, Theories of Minds, and Executive Functions" (Agnes Melinda Kovacs and Erno Teglas); "Unconventional Thinking for Speaking: The Blends of George W. Bush" (Alan Cienki); "Blends of Alternations in the Grammar of Brazilian Vernacular…

  14. Minimally invasive therapy in Denmark.

    PubMed

    Schou, I

    1993-01-01

    Minimally invasive therapy (MIT) is beginning to have impacts on health care in Denmark, although diffusion has been delayed compared to diffusion in other European countries. Now policy makers are beginning to appreciate the potential advantages in terms of closing hospitals and shifting treatment to the out-patient setting, and diffusion will probably go faster in the future. Denmark does not have a system for technology assessment, neither central nor regional, and there is no early warning mechanism to survey international developments. This implies lack of possibilities for the planning of diffusion, training, and criteria for treatment.

  15. Educational and Vocational Guidance in Denmark. Education in Denmark.

    ERIC Educational Resources Information Center

    Ministry of Education, Copenhagen (Denmark).

    This report sketches educational and vocational guidance in Denmark. It begins with a historical account of developments in the areas of career and school counseling. Outlined next are guidance programs at the following levels: folkeskole, gymnasium and studenterkursus (upper secondary education), higher preparatory examination, vocational school,…

  16. Family Day Care in Denmark.

    ERIC Educational Resources Information Center

    Wagner, Mary; Wagner, Marsden G.

    The present report describes a system for the care of children during the day in Denmark: care in private family homes. Begun in 1966, this program organized a formal system of family day care homes initiated and supervised by the government; this is an extension of the former system of licensing privately initiated family day care homes. From the…

  17. Application of Molecular Typing Results in Source Attribution Models: The Case of Multiple Locus Variable Number Tandem Repeat Analysis (MLVA) of Salmonella Isolates Obtained from Integrated Surveillance in Denmark.

    PubMed

    de Knegt, Leonardo V; Pires, Sara M; Löfström, Charlotta; Sørensen, Gitte; Pedersen, Karl; Torpdahl, Mia; Nielsen, Eva M; Hald, Tine

    2016-03-01

    Salmonella is an important cause of bacterial foodborne infections in Denmark. To identify the main animal-food sources of human salmonellosis, risk managers have relied on a routine application of a microbial subtyping-based source attribution model since 1995. In 2013, multiple locus variable number tandem repeat analysis (MLVA) substituted phage typing as the subtyping method for surveillance of S. Enteritidis and S. Typhimurium isolated from animals, food, and humans in Denmark. The purpose of this study was to develop a modeling approach applying a combination of serovars, MLVA types, and antibiotic resistance profiles for the Salmonella source attribution, and assess the utility of the results for the food safety decisionmakers. Full and simplified MLVA schemes from surveillance data were tested, and model fit and consistency of results were assessed using statistical measures. We conclude that loci schemes STTR5/STTR10/STTR3 for S. Typhimurium and SE9/SE5/SE2/SE1/SE3 for S. Enteritidis can be used in microbial subtyping-based source attribution models. Based on the results, we discuss that an adjustment of the discriminatory level of the subtyping method applied often will be required to fit the purpose of the study and the available data. The issues discussed are also considered highly relevant when applying, e.g., extended multi-locus sequence typing or next-generation sequencing techniques.

  18. Energy use in Denmark: An international perspective

    SciTech Connect

    Schipper, L.; Howarth, R.; Andersson, B.; Price, L.

    1992-08-01

    This report analyzes the evolution use in Denmark since the early 1970s in order to shed light on the future path of energy use in Denmark, with particular emphasis on the role of energy efficiency. The authors found that improvements in end-use energy efficiency reduced primary energy requirements in Denmark by 22% between 1972 and 1988. Focusing on developments in six individual sectors of the Danish economy (residential, manufacturing, other industry, service, travel, and freight), they found that the residential, manufacturing, and service sectors have led the improvements in efficiency. Travel showed few significant improvements and the efficiency of freight transportation worsened. The international comparisons showed that the structure of energy use in Denmark is less energy-intensive than that of most high-income OECD countries, with the exception of Japan. Overall, they concluded that most of the energy savings achieved in Denmark were brought about through improvements in technology. They also found that an important stimulus for improved efficiency was higher energy prices, led in no small part by significant taxes imposed on small consumers of heating oil, electricity, and motor fuels. Energy-efficiency programs accelerated energy savings in homes and commercial buildings. The rate of improvement of energy efficiency in Denmark has slowed down significantly since 1984, consistent with trends observed in other major countries. While many of the energy-efficiency goals stated or implied in Denmark`s Energi 2000 are achievable over a very long period, present trends do not point towards achievement of these goals by 2010 or even 2020. Strong measures will have to be developed by both public and private authorities if energy efficiency is to make a key contributions to reducing environmental problems associated with energy use in Denmark.

  19. eHealth in Denmark: a case study.

    PubMed

    Kierkegaard, Patrick

    2013-12-01

    Denmark is widely regarded as a leading country in terms of eHealth integration and healthcare delivery services. The push for eHealth adoption over that past 20 years in the Danish health sector has led to the deployment of multiple eHealth technologies. However, in reality the Danish healthcare suffers from eHealth system fragmentation which has led to eHealth's inability to reach full potential in delivering quality healthcare service. This paper will presents a case study of the current state of eHealth in the Danish healthcare system and discuss the current challenges the country is facing today.

  20. "Left to Your Own Devices"--The Missed Potential of Adult Career Guidance in Denmark

    ERIC Educational Resources Information Center

    Cort, Pia; Thomsen, Rie; Mariager-Anderson, Kristina

    2015-01-01

    In 2008, the European Council agreed on a Resolution on better integrating lifelong guidance into lifelong learning strategies. The Resolution promoted lifelong guidance as a policy to support people during the multiple transitions provoked by a more volatile labour market. However, when looking into the guidance policy of Denmark, the Resolution…

  1. The Spanish flu in Denmark.

    PubMed

    Kolte, Ida Viktoria; Skinhøj, Peter; Keiding, Niels; Lynge, Elsebeth

    2008-01-01

    The spread of H5N1 influenza and the similarity between this avian virus and the Spanish flu virus causes fear of a new influenza pandemic, but data from the Spanish flu may also be of guidance in planning for preventive measures. Using data on influenza cases, influenza deaths and total deaths for Denmark and for Danish towns from 1917 to 1921, and population data from the 1916 and 1921 censuses, we analysed incident cases, cumulative, age-specific and age-standardized rates. Overall, more than 900,000 persons contracted flu during the y 1918-1920, and 1 out of 50 patients died from the disease. An early wave of the flu occurred in the capital and major towns, but not in peripheral towns. Influenza incidence in 1918 peaked at age 5-15 y, closely followed by the age groups 1-5 y and 15-65 y, but the influenza mortality was highest in the age groups 0-1 y and 15-65 y, with a peak mortality at age 20-34 y producing a W curve for mortality by age. The background for the better outcome in children aged 1-15 y as well as for the disease immunity in the elderly population should be further investigated.

  2. Denmark's Boernehavens: A Place to Grow

    ERIC Educational Resources Information Center

    Mecham, Neil A.

    2010-01-01

    During the author's trips to Denmark as an instructor of American college students studying abroad, he led groups to visit several "boernehavens," which are the Danish equivalents of U.S. preschools for children ages 3 to 5. Danish society values confident individuals who can take initiative when faced with challenges and opportunities.…

  3. The Financing of Continuing Training in Denmark.

    ERIC Educational Resources Information Center

    Hedegaard, Birthe

    In Denmark, suppliers of continuing training constitute the point at which the sources of finance meet the people who receive continuing training. On the basis of this close connection between training suppliers and the financial sources behind them, continuing training activities can be subdivided into these five categories: (1) continuing…

  4. The Seeds of Social Change from Denmark.

    ERIC Educational Resources Information Center

    Roberson, Donald N., Jr.

    N.F.S. Grundtvig was a priest, historian, poet, and founder of the Danish Folk High School. He believed that education for adults should be geared to adults and wanted schools to be independent of the church. Grundtvig was among the first to call for Denmark's schools to use the native Danish language. Grundtvig believed that each group or culture…

  5. Comparing Teacher Roles in Denmark and England

    ERIC Educational Resources Information Center

    Kelly, Peter; Dorf, Hans; Pratt, Nick; Hohmann, Ulrike

    2014-01-01

    This article reports the findings of a comparative study of teaching in Denmark and England. Its broader aim is to help develop an approach for comparing pedagogy. Lesson observations and interviews identified the range of goals towards which teachers in each country worked and the actions these prompted. These were clustered using the lens of…

  6. The development of family nursing in Denmark: current status and future perspectives.

    PubMed

    Østergaard, Birte; Wagner, Lis

    2014-11-01

    Over the past 12 years, a strong foundation for family nursing has been built in Denmark, with rapid growth in the past 3 years. A review of nursing research conducted in Denmark and published between 2002 and 2013 found 15 studies that examined family phenomena. The majority of the studies used descriptive methods with data collected from surveys and interviews involving family members either together or individually. Only five of the studies examined interventions that included families' perspectives about the intervention being evaluated. Several current research projects lead by Danish nurses examine the implementation of family nursing knowledge to clinical settings. Integration of family nursing theory has begun in Denmark in undergraduate and graduate nursing curricula and in May 2013, the Danish Family Nursing Association was officially established. Infrastructure and financial conference support has made it possible to invite Nordic and international colleagues to meet in Denmark, which, reciprocally, expands understanding and support for family nursing within the country. Further collaboration between Danish nurse researchers, educators, and administrators will help sustain the growth of family nursing science and its application in family-focused nursing practice.

  7. Integration

    ERIC Educational Resources Information Center

    Kalyn, Brenda

    2006-01-01

    Integrated learning is an exciting adventure for both teachers and students. It is not uncommon to observe the integration of academic subjects such as math, science, and language arts. However, educators need to recognize that movement experiences in physical education also can be linked to academic curricula and, may even lead the…

  8. The burden of fungal disease in Denmark.

    PubMed

    Mortensen, Klaus L; Denning, David W; Arendrup, Maiken C

    2015-10-01

    The aim of this study is to calculate the burden of fungal disease in Denmark. We identified all published epidemiology papers reporting fungal infection rates in Denmark. Where no data existed, we used numbers of specific populations at risk and fungal infection frequencies in those populations to estimate national incidence or prevalence. Approximately, one in six Danes will suffer from a fungal infection each year, most of which are skin or mucosal diseases causing disability but no deaths. Good data exist on candidaemia where a national voluntary reporting system is in place and have shown a high rate (9.6 per 100,000 inhabitants) compared other European countries. We present estimates of invasive aspergillosis and chronic pulmonary aspergillosis with rates of 4.4 per 100,000 and 3.1 per 100,000 inhabitants, respectively. Further studies are needed in order to better ascertain high-burden fungal infections such as recurrent vulvovaginal candidiasis (~1350 cases in 100,000 women) as well as allergic bronchopulmonary aspergillosis (~131 cases in 100,000 inhabitants) and severe asthma with fungal sensitisation (cases in 100,000 inhabitants). In conclusion, more than 93,000 Danes or about 2% of Denmark's population will have a non-trivial fungal infection during 1 year, which underscores the magnitude of the fungal burden.

  9. On the hydrography of Denmark Strait

    NASA Astrophysics Data System (ADS)

    Mastropole, Dana; Pickart, Robert S.; Valdimarsson, Hédinn; Vâge, Kjetil; Jochumsen, Kerstin; Girton, James

    2017-01-01

    Using 111 shipboard hydrographic sections across Denmark Strait occupied between 1990 and 2012, we characterize the mean conditions at the sill, quantify the water mass constituents, and describe the dominant features of the Denmark Strait Overflow Water (DSOW). The mean vertical sections of temperature, salinity, and density reveal the presence of circulation components found upstream of the sill, in particular the shelfbreak East Greenland Current (EGC) and the separated EGC. These correspond to hydrographic fronts consistent with surface-intensified southward flow. Deeper in the water column the isopycnals slope oppositely, indicative of bottom-intensified flow of DSOW. An end-member analysis indicates that the deepest part of Denmark Strait is dominated by Arctic-Origin Water with only small amounts of Atlantic-Origin Water. On the western side of the strait, the overflow water is a mixture of both constituents, with a contribution from Polar Surface Water. Weakly stratified "boluses" of dense water are present in 41% of the occupations, revealing that this is a common configuration of DSOW. The bolus water is primarily Arctic-Origin Water and constitutes the densest portion of the overflow. The boluses have become warmer and saltier over the 22 year record, which can be explained by changes in end-member properties and their relative contributions to bolus composition.

  10. GPR Use and Activities in Denmark

    NASA Astrophysics Data System (ADS)

    Ringgaard, Jørgen; Wisén, Roger

    2014-05-01

    Academic work on GPR in Denmark is performed both by the Technical University of Denmark (DTU) and the University of Copenhagen (KU). The work at DTU includes development of antennas and systems, e.g. an airborne ice-sounder GPR system (POLARIS) that today is in frequent use for monitoring of ice thickness in Greenland. DTU often collaborates with ESA (European Space Agency) regarding electromagnetic development projects. At KU there is an ongoing work with GPR applied to water resources. The main objective is to study flux of water and matter across different hydrological domains. There are several recent publications from KU describing research for data analysis and modelling as well as hydro geophysical applications. Also the Geological Survey of Denmark and Greenland (GEUS) performs frequent geological mapping with GPR. There have been mainly two actors on the Danish commercial market for several years: FalkGeo and Ramboll. Falkgeo has been active for many years acquiring data for several different applications such as archeology, utilities and roads. Their equipment pool comprises both a multichannel Terravision system form GSSI and a 2D system from Mala Geoscience with a comprehensive range of antennas. Ramboll has performed GPR surveys for two decades mainly with 2D systems from GSSI. In recent years Ramboll has also obtained a system with RTA antennas from Mala Geoscience and a multichannel system from 3D-Radar. These systems have opened markets both for deeper geological mapping and for shallow mapping. The geological mapping with the Mala system has often been combined with resistivity imaging (CVES) and refraction seismic. The 3D system has been applied in airports and on road for mapping of layer thicknesses, delamination and for control of asphalt works. Other areas comprise bridge deck evaluation and utility mapping. Ramboll also acts as client advisor for BaneDanmark, a state owned company who operates and develops the Danish state railway network

  11. Fireball over Denmark on 17 January 2009

    NASA Astrophysics Data System (ADS)

    Zoladek, P.; Wiśniewski, Mariusz; Polakowski, K.

    2009-12-01

    A spectacular fireball crossed the sky over Denmark on 17 January 2009. It was observed by many eyewitnesses across northern Europe, but only recorded by a single camera from Sweden. Two Polish Fireball Network cameras managed to indirectly record the fireball due to changes in sky brightness. As a result of careful analysis of video footage and reports from the eyewitnesses we were able to determine the trajectory of the object. The velocity of the fireball was estimated at 50 km/s. A meteor event with such a rapid velocity should not produce any meteorites.

  12. OECD Review of Career Guidance Policies. Denmark: Country Note.

    ERIC Educational Resources Information Center

    Organisation for Economic Cooperation and Development, Paris (France).

    Denmark's career guidance system and policies were evaluated. The review team met with policymakers and guidance practitioners in the public and private sectors, analyzed data from a national questionnaire, and reviewed pertinent documentation. The evaluation focused on the following areas: coordinating mechanisms; the role of Denmark's National…

  13. Cancer in printing workers in Denmark.

    PubMed Central

    Lynge, E; Rix, B A; Villadsen, E; Andersen, I; Hink, M; Olsen, E; Møller, U L; Silfverberg, E

    1995-01-01

    OBJECTIVES--To study the cancer incidence in printing workers in Denmark. METHODS--The cohort of 15,534 men and 3593 women working in the printing industry in 1970 were followed up for death, emigrations, and incident cancer cases until the end of 1987. Their cancer incidence was compared with that of all economically active people in Denmark. The smoking and drinking habits reported by members of the printing trade unions at a survey in 1972 were compared with habits reported by members of other trade unions. RESULTS--Lung, bladder, renal pelvis, and primary liver cancers were in excess among the printing workers. The excess risks of lung cancer among the factory workers in newspaper and magazine production, of bladder cancer in typographers in printing establishments, of renal pelvis cancer in typographers and lithographers, and of primary liver cancer among lithographers and bookbinders exceeded those expected based on the reported smoking and drinking habits. CONCLUSION--Our results indicate, in line with a previous study from Manchester, that work with rotary letterpress printing was associated with an increased risk of lung cancer. The inconsistent results from studies on bladder cancer in printing workers may point to a risk confined to a certain subgroup. The sixfold risk of primary liver cancer in Danish lithographers warrants studies in other countries. PMID:8535493

  14. Registers of multiple sclerosis in Denmark.

    PubMed

    Koch-Henriksen, N; Magyari, M; Laursen, B

    2015-01-01

    There are two nationwide population-based registers for multiple sclerosis (MS) in Denmark. The oldest register is The Danish Multiple Sclerosis Registry (DMSR), which is an epidemiological register for estimation of prevalence and incidence of MS and survival, and for identifying exposures earlier in life that may affect the risk of MS. This register has no systematic follow-up data except for survival. The DMSR has over the years published nationwide incidence- and prevalence data from Denmark and has been involved in a number of 'historical prospective' studies to elucidate the association between a number of different environmental exposures in the past and the subsequent risk of MS. Some of these studies have been able to exonerate suspected risk factors. The other register, the nationwide Danish Multiple Sclerosis Treatment Register, is a follow-up register for all patients who have received disease-modifying treatments since 1996. It has, in particular, contributed to the knowledge of the role of antibodies against the biological drugs used for the treatment of MS.

  15. Towards 50% wind electricity in Denmark: Dilemmas and challenges

    NASA Astrophysics Data System (ADS)

    Bach, Paul-Frederik

    2016-05-01

    Electricity and heat supply systems are essential contributors to a fossil-free future in Denmark. The combined production of heat and power (CHP) and the production of wind energy are already well developed in Denmark. Combined heat and power covers about 40% of the demand for space heating in Denmark, and the production of wind energy is supposed to exceed 50% of the demand for electricity by 2020. The changing electricity and heat production has some consequences already now: i) Decreasing wholesale prices in Denmark and in other countries. ii) Thermal power plants are closing down. Denmark is no longer self-sufficient with electricity under all conditions. iii) The electricity production pattern does not match the demand pattern. The result is that the neighbouring countries must absorb the variations from wind and solar power. Essential challenges: i) The future of combined heat and power in Denmark is uncertain. ii) Denmark will need new backup capacity for filling the gaps in wind power and solar cell output. iii) Flexible electricity consumers are supposed to contribute to balancing the future power systems. There is still a long way to go before the Smart Grid visions are implemented in large scale. iv) The transformation of the power system will create new risks of power failures.

  16. Towards Universal Design Hotels in Denmark.

    PubMed

    Grangaard, Sidse

    2016-01-01

    Based on the research project 'Accessible Hotel Rooms' that studies the balance between the experience of supply and demand regarding accessibility features in Danish hotel rooms, this paper demonstrates factors having an influence on Universal Design hotels in Denmark. The research project was financed by the Danish Transport and Construction Agency. Different notions in the hotel sector of the current supply and demand for Universal Design hotel rooms are identified, as well as future demand. Despite supplying accessible rooms, some hotels do not advertise their accessibility features on their website. There exists an attitude in the hotel sector that functions as a barrier for Universal Design: if there are enough guests, for example business travellers, then why market the hotel on Universal Design? The paper points out the coherence between the understanding of the users and the view of demand. Another important factor is Corporate Social Responsibility, which can be regarded as a strategy or platform towards Universal Design hotels.

  17. Delay in diagnosis: the experience in Denmark

    PubMed Central

    Olesen, F; Hansen, R P; Vedsted, P

    2009-01-01

    Background: Denmark has poorer 5-year survival rates than many other Western European countries, and cancer patients tend to have more advanced stages at diagnosis than those in other Scandinavian countries. Part of this may be due to delay in diagnosis. The aim of this paper is to give an overview of the initiatives currently underway to reduce delays. Methods: Description of Danish actions to reduce delay. Results: Results of surveys of patient-, doctor- and system-related delays are presented and so are the political initiatives to ensure that cancer is seen as an acute disease. Conclusion: In future, fast-track diagnosis and treatment will be provided for suspected cancers and access to general diagnostic investigations will be improved. A large national experiment with cancer seen as an acute disease is currently being implemented, and as yet the results are unknown. PMID:19956163

  18. Regional geothermal 3D modelling in Denmark

    NASA Astrophysics Data System (ADS)

    Poulsen, S. E.; Balling, N.; Bording, T. S.; Nielsen, S. B.

    2012-04-01

    In the pursuit of sustainable and low carbon emission energy sources, increased global attention has been given to the exploration and exploitation of geothermal resources within recent decades. In 2009 a national multi-disciplinary geothermal research project was established. As a significant part of this project, 3D temperature modelling is to be carried out, with special emphasis on temperatures of potential geothermal reservoirs in the Danish area. The Danish subsurface encompasses low enthalpy geothermal reservoirs of mainly Triassic and Jurassic age. Geothermal plants at Amager (Copenhagen) and Thisted (Northern Jutland) have the capacity of supplying the district heating network with up to 14 MW and 7 MW, respectively, by withdrawing warm pore water from the Gassum (Lower Jurassic/Upper Triassic) and Bunter (Lower Triassic) sandstone reservoirs, respectively. Explorative studies of the subsurface temperature regime typically are based on a combination of observations and modelling. In this study, the open-source groundwater modelling code MODFLOW is modified to simulate the subsurface temperature distribution in three dimensions by taking advantage of the mathematical similarity between saturated groundwater flow (Darcy flow) and heat conduction. A numerical model of the subsurface geology in Denmark is built and parameterized from lithological information derived from joint interpretation of seismic surveys and borehole information. Boundary conditions are constructed from knowledge about the heat flow from the Earth's interior and the shallow ground temperature. Matrix thermal conductivities have been estimated from analysis of high-resolution temperature logs measured in deep wells and porosity-depth relations are included using interpreted main lithologies. The model takes into account the dependency of temperature and pressure on thermal conductivity. Moreover, a transient model based correction of the paleoclimatic thermal disturbance caused by the

  19. A 'civic turn' in Scandinavian family migration policies? Comparing Denmark, Norway and Sweden.

    PubMed

    Bech, Emily Cochran; Borevi, Karin; Mouritsen, Per

    2017-01-01

    Family migration policy, once basing citizens and resident foreigners' possibilities to bring in foreign family members mainly on the right to family life, is increasingly a tool states use to limit immigration and to push newcomers to integrate into civic and economic life. The family migration policies of Denmark, Norway and Sweden range widely - from more minimal support and age requirements to high expectations of language skills, work records and even income levels. While in Denmark and increasingly in Norway growing sets of requirements have been justified on the need to protect the welfare state and a Nordic liberal way of life, in Sweden more minimal requirements have been introduced in the name of spurring immigrants' labor market integration even as rights-based reasoning has continued to dominate. In all three countries, new restrictions have been introduced in the wake of the refugee crisis. These cases show how prioritizations of the right to family life vis-à-vis welfare-state sustainability have produced different rules for family entry, and how family migration policies are used to different extents to push civic integration of both new and already settled immigrants.

  20. Source apportionment of particulate matter in Denmark

    NASA Astrophysics Data System (ADS)

    Moenster, J.; Glasius, M.; Nielsen, O. J.; Bilde, M.; Jensen, F. P.

    2005-12-01

    Atmospheric particulate matter (PM) has received considerable attention over the last decade as an important component of air pollution, particularly due to its health effects on the exposed population. Typically the mass of particles with diameters smaller that 10 μm (PM10) has been used in large cohort studies to estimate health effects such as increase in hospitalization rate, asthma attacks and premature deaths. Particles smaller than 2.5 μm (PM2.5) and ultra fine particles have been used in various epidemiological studies and correlations between exposure to fine and ultra fine particles and health effects have been found. Limits of acceptable concentrations of PM10, PM2.5 and some carcinogenic species have been made, and it is important to find the origin of the particulate matter to prevent exceeds of these limits. This can be done by measuring particle mass, organic/inorganic fractions of particles, the chemical components and other relevant factors, and then use receptor modeling for source apportionment of the particulate matter. We have done measurements at street level and urban background in Copenhagen, Denmark, to determine the origin of different sizes of particulate matter and the toxic organic compounds connected to these particles. We also did measurements in a small village with less traffic and more residential wood combustion for a comparison between traffic and wood combustion generated pollution. Our results show a significant amount of particulate matter coming from non local sources and are dominated by long-range transported inorganic salts. The amount of these is highly depended on the wind direction and thus on the origin of the wind plume. The origin of the carcinogenic organic compound benzo(a)pyrene was found to be local combustion sources. To prevent events of high particulate matter concentration in Copenhagen, Denmark, a reduction of emission from the local traffic will only lead to a minor effect, since the majority of the

  1. Occupational risks of sinonasal cancer in Denmark.

    PubMed

    Olsen, J H

    1988-05-01

    A new comprehensive data linkage system for the detailed investigation of occupational cancer has been established in the Danish Cancer Registry, providing employment histories back to 1964. All 382 cases of cancers of the sinonasal cavities diagnosed between 1970 and 1984 and kept on file in this data linkage system were analysed using standardised proportional incidence ratios (SPIR) to screen for industrial high risk areas for these malignancies in Denmark. Excess risks were confirmed among men and women employed in the manufacture of footwear and other leather products and of wooden furniture. No risk significantly above expectancy was observed among wood workers outside the furniture making industry. Excess risks were also seen among men in all areas of basic metal industries (SPIR = 184-562) and in a subset of workers in industries producing metal containers (SPIR = 329-600). Most unexpected were raised risks among employees of both sexes in making cocoa, chocolate, and sugar confectionery (SPIR = 535 for men and 860 for women); these, in combination with the observed risks among female employees in canning and preserving fruits and vegetables (SPIR = 778) and in farming (SPIR = 735) may point to a common aetiology. The obscuring effect of mass significance may, however, be another explanation. The new associations discovered in this large scale linkage study must therefore await further confirmation.

  2. Occupational risks of sinonasal cancer in Denmark.

    PubMed Central

    Olsen, J H

    1988-01-01

    A new comprehensive data linkage system for the detailed investigation of occupational cancer has been established in the Danish Cancer Registry, providing employment histories back to 1964. All 382 cases of cancers of the sinonasal cavities diagnosed between 1970 and 1984 and kept on file in this data linkage system were analysed using standardised proportional incidence ratios (SPIR) to screen for industrial high risk areas for these malignancies in Denmark. Excess risks were confirmed among men and women employed in the manufacture of footwear and other leather products and of wooden furniture. No risk significantly above expectancy was observed among wood workers outside the furniture making industry. Excess risks were also seen among men in all areas of basic metal industries (SPIR = 184-562) and in a subset of workers in industries producing metal containers (SPIR = 329-600). Most unexpected were raised risks among employees of both sexes in making cocoa, chocolate, and sugar confectionery (SPIR = 535 for men and 860 for women); these, in combination with the observed risks among female employees in canning and preserving fruits and vegetables (SPIR = 778) and in farming (SPIR = 735) may point to a common aetiology. The obscuring effect of mass significance may, however, be another explanation. The new associations discovered in this large scale linkage study must therefore await further confirmation. PMID:3378013

  3. Hospital admissions among male drivers in Denmark

    PubMed Central

    Hannerz, H; Tuchsen, F

    2001-01-01

    OBJECTIVES—To facilitate decisions about interventions and to establish baseline values for future evaluation of preventive efforts, the aim of the present study was to elucidate the disease pattern among male professional drivers in Denmark. The study differentiated between drivers of goods vehicles and drivers of passenger transport.
METHODS—Cohorts of all 20-59 year old Danish male professional drivers in the years 1981, 1986, 1991, and 1994 were formed, to calculate age standardised hospital admission ratios (SHRs) and time trends (1981-97) for many diagnostic aggregations.
RESULTS—SHRs for diseases in practically all systems and organs of the body were higher among professional drivers than they were in the male working population at large. Also drivers of passenger transport, compared with drivers of goods vehicles, had significantly high SHRs due to infectious and parasitic diseases, diseases of the circulatory system, and diseases of the respiratory system, and significantly lower rates of injury. For both driver groups, the SHRs for acute myocardial infarction increased with time whereas the SHR for acute gastritis decreased, and for drivers of passenger transport an increasing SHR for chronic obstructive pulmonary disease, was found over time.
CONCLUSION—Drivers of passenger transport and drivers of goods vehicles differ in their disease patterns. The results support the hypothesis that preventive efforts are needed in both groups, but underline that different strategies are required for different categories of drivers.


Keywords: professional drivers; hospital admissions; surveillance system PMID:11245742

  4. The existential dimension in general practice: identifying understandings and experiences of general practitioners in Denmark

    PubMed Central

    Assing Hvidt, Elisabeth; Søndergaard, Jens; Ammentorp, Jette; Bjerrum, Lars; Gilså Hansen, Dorte; Olesen, Frede; Pedersen, Susanne S.; Timm, Helle; Timmermann, Connie; Hvidt, Niels Christian

    2016-01-01

    Objective The objective of this study is to identify points of agreement and disagreements among general practitioners (GPs) in Denmark concerning how the existential dimension is understood, and when and how it is integrated in the GP–patient encounter. Design A qualitative methodology with semi-structured focus group interviews was employed. Setting General practice setting in Denmark. Subjects Thirty-one GPs from two Danish regions between 38 and 68 years of age participated in seven focus group interviews. Results Although understood to involve broad life conditions such as present and future being and identity, connectedness to a society and to other people, the existential dimension was primarily reported integrated in connection with life-threatening diseases and death. Furthermore, integration of the existential dimension was characterized as unsystematic and intuitive. Communication about religious or spiritual questions was mostly avoided by GPs due to shyness and perceived lack of expertise. GPs also reported infrequent referrals of patients to chaplains. Conclusion GPs integrate issues related to the existential dimension in implicit and non-standardized ways and are hindered by cultural barriers. As a way to enhance a practice culture in which GPs pay more explicit attention to the patients’ multidimensional concerns, opportunities for professional development could be offered (courses or seminars) that focus on mutual sharing of existential reflections, ideas and communication competencies. Key pointsAlthough integration of the existential dimension is recommended for patient care in general practice, little is known about GPs’ understanding and integration of this dimension in the GP–patient encounter.The existential dimension is understood to involve broad and universal life conditions having no explicit reference to spiritual or religious aspects.The integration of the existential dimension is delimited to patient cases where life

  5. Snapshots of Language and Literature Teaching in Denmark and England

    ERIC Educational Resources Information Center

    Kelly, Peter; Dorf, Hans

    2016-01-01

    To illustrate differences in lower secondary-level language and literature teaching, we contrast a typical teaching episode in Denmark with one in England. Both reflect the dominant discourses in each country alongside recent policy initiatives, and each exemplifies a different orientation to language and literature teaching focussing on…

  6. Source Country Differences in Test Score Gaps: Evidence from Denmark

    ERIC Educational Resources Information Center

    Rangvid, Beatrice Schindler

    2010-01-01

    We combine data from three studies for Denmark in the PISA 2000 framework to investigate differences in the native-immigrant test score gap by country of origin. In addition to the controls available from PISA data sources, we use student-level data on home background and individual migration histories linked from administrative registers. We find…

  7. Helping Mothers in Denmark: Over Two Centries of Experience.

    ERIC Educational Resources Information Center

    Wagner, Mary M.; Wagner, Marsden G.

    In Denmark a large and complex group of social, legal, educational, health, and financial services are available to all women who are pregnant and/or have children under 2 years of age. These services are the subject of two joint reports. The first report describes the history, organization, and administration of the program and the services for…

  8. The Development of Educational Accountability in China and Denmark

    ERIC Educational Resources Information Center

    Rasmussen, Palle; Zou, Yihuan

    2014-01-01

    In recent decades, the concept of accountability has attracted more and more attention in public governance and management. The management of education is no exception. This article presents and discusses the evolution and current status of educational accountability in two different national contexts, China and Denmark. Two main sectors of…

  9. Comparing Pedagogy in Mathematics in Denmark and England

    ERIC Educational Resources Information Center

    Kelly, Peter; Pratt, Nick; Dorf, Hans; Hohmann, Ulrike

    2013-01-01

    This article reports the findings of a comparative study of pedagogy in lower-secondary school mathematics in Denmark and England. Lesson observations and interviews identified the range of goals towards which teachers in each country worked and the actions these prompted. These were clustered using the lens of Bernstein's pedagogic discourse to…

  10. Vocational Education and Training in Denmark. Short Description

    ERIC Educational Resources Information Center

    Cedefop - European Centre for the Development of Vocational Training, 2012

    2012-01-01

    Vocational education and training in Denmark has embarked on a process of modernisation aiming at, primarily, increasing flexibility, and individualisation, quality and efficiency. Assessment and recognition of informal and non-formal learning, competence-based curricula, innovative approaches to teaching, and increased possibilities for partial…

  11. University Governance in Denmark: From Democracy to Accountability?

    ERIC Educational Resources Information Center

    Carney, Stephen

    2006-01-01

    This article reports the findings of a Danish research council-funded project aimed at exploring a comprehensive package of management reforms in higher education instituted in Denmark since 2003. The reforms attempt to change not only the way institutions are governed but the very notion of democracy and engagement in higher education. In short,…

  12. Health Visiting in the Infant's Home in Denmark.

    ERIC Educational Resources Information Center

    Wagner, Mary; Wagner, Marsden G.

    A program of infant home visiting was established in Denmark as a result of concern about the rate of infant mortality. The objectives, problems, and promise of the infant Home Visiting Program are summarized and evaluated in terms of their implications for the United States. Although the results of the program have been overwhelmingly favorable…

  13. Recurrent Education: Policy and Development in OECD Member Countries. Denmark.

    ERIC Educational Resources Information Center

    Hansen, Berrit

    The report on recurrent education in Denmark is one of a series describing continuation education in OECD member countries. Intended as a means of liberating individuals from the education-work-leisure-retirement sequence, recurrent education provides freedom to mix and alternate these phases of life within the limits of the socially possible.…

  14. The Progressive Development of Environmental Education in Sweden and Denmark

    ERIC Educational Resources Information Center

    Breiting, Soren; Wickenberg, Per

    2010-01-01

    Our paper traces the history and progressive development of environmental education and education for sustainable development (ESD) in Sweden and Denmark. Our main focus is on work in primary and lower secondary schools as part of a search for trends of international interest related to the conceptualisation and practice of environmental education…

  15. [Prevalence, symptoms, and diagnosis of tuberculosis in Denmark].

    PubMed

    Hilberg, Ole; Hyldgaard, Charlotte; Løkke, Anders

    2011-03-21

    In Denmark the prevalence of tuberculosis (TB) is low, but updated knowledge on the diagnostic techniques available is still important. We summarise the current procedure for diagnosing TB with emphasis on sputum culture, use of interferon gamma release assays and the clinical and radiological manifestations of tuberculosis.

  16. Pesticide Reduction Programs in Denmark, the Netherlands, and Sweden.

    ERIC Educational Resources Information Center

    Hurst, Peter

    1992-01-01

    The Netherlands, Denmark, and Sweden are leaders in introducing comprehensive and targeted risk reduction programs for pesticides. Describes these programs and their implementation, incorporating material obtained through interviews with representatives of the main constituencies involved in reduction Tables list pesticides that do not meet the…

  17. Educational assortative mating and income inequality in Denmark.

    PubMed

    Breen, Richard; Andersen, Signe Hald

    2012-08-01

    Many writers have expressed a concern that growing educational assortative mating will lead to greater inequality between households in their earnings or income. In this article, we examine the relationship between educational assortative mating and income inequality in Denmark between 1987 and 2006. Denmark is widely known for its low level of income inequality, but the Danish case provides a good test of the relationship between educational assortative mating and inequality because although income inequality increased over the period we consider, educational homogamy declined. Using register data on the exact incomes of the whole population, we find that change in assortative mating increased income inequality but that these changes were driven by changes in the educational distributions of men and women rather than in the propensity for people to choose a partner with a given level of education.

  18. The geomagnetic elements in Denmark 1928-1980

    NASA Astrophysics Data System (ADS)

    Hansen, H. A.

    Geomagnetic surveys in Denmark from 1928 till 1980 are reported. The Danish Meteorological Institute initiated a new, geomagnetic survey of Denmark in 1928 by the establishment of 10 repeat statins for observation of the geomagnetic, secular variation. The stations were visited again in 1930 and since then every fifth year. The general survey was started in 1939 and continued during the years 1946 to 1957 with the mapping of Northern Jutland. In 1967 the survey taken with a coarser spacing of the measured points during the following years succeeded in completing the mapping of the country with primary consideration to the declination. The observations on the repeat stations during the time 1928-1980 allowed development of mathematical formulas for the secular change of the magnetic elements D, H and Z at any arbitrary point in the country.

  19. The long range transport of birch (Betula) pollen from Poland and Germany causes significant pre-season concentrations in Denmark

    NASA Astrophysics Data System (ADS)

    Ambelas Skjoth, C.; Sommer, J.; Stach, A.; Smith, M.; Brandt, J.; Christensen, J. H.; Frohn, L. M.; Geels, C.; Hansen, K. M.; Hedegaard, G. B.

    2009-04-01

    In Denmark, where birch pollen is considered to be among the most important allergenic pollen, about one million people suffer from seasonal allergic rhinitis. In Denmark, the official reported pollen forecast is based on the daily weather forecast, the pollen calendar and local 24-h measurements. Birch pollen has the potential for long-range transport but the present Danish pollen forecast does not account for birch pollen being transported into the country from distant sources.. Long-range transport episodes are intermittent and often out of the main pollen season, where individuals in general will be medically unprotected. Here we use an integrated approach to investigate whether or not Denmark receives significant quantities of birch pollen from Poland and Germany before local trees start to flower. In 2006 we used a combination of phenological observations and pollen measurements in Poland (Poznań) and Denmark (Copenhagen). Seasonal and diurnal variations in birch pollen measurement from Copenhagen (2000-2006) were examined with the aim of identifying pre-seasonal episodes originating from long-range transport. The 2.5% accumulation method was used for identifying start of season. If daily pollen counts exceeded 30 grains/m3 either before the local flowering season began or on the actual start day, the episode was chosen for investigation with back trajectory analysis. A birch forest inventory for Northern Europe was produced and implemented in DEHM-Pollen along with a simple unified pollen release model SUPREME to investigate the 2006 campaign in detail. In 2006, full flowering took place in Poznan between 20th and 28th of April and daily concentrations varied between 739 and 2169 grains/m3. In Copenhagen phenological observations showed that local flowering was initiated the 2nd of May. In Copenhagen several episodes with pollen concentrations at 108, 244 and 41 grains/m3 were recorded the 23rd, 26th and 27th of April, respectively. Back-trajectory analysis

  20. Gendered Time-Crunch and Work Factors in Denmark

    ERIC Educational Resources Information Center

    Deding, Mette; Lausten, Mette

    2011-01-01

    Being crunched for time is an important aspect of life quality. Although Denmark is a country known for gender-equality, on average mothers are more time-crunched than fathers. We show this using a representative sample of Danish dual-earner couples with at least one child aged 0-10 years. We analyze the determinants of time-crunch in relation to…

  1. A Cost Analysis of Day Care in Denmark.

    ERIC Educational Resources Information Center

    Wagner, Marsden G.

    A cost analysis of day care in Denmark was initiated to determine what day care services cost, who pays for them, and how these costs relate to the quality of day care services. Some of the findings are: (1) group day care is considerably more expensive for children 0-3 years of age than for children 3-7 years of age; (2) group day care centers…

  2. ESRO/ESA and Denmark. Participation by research and industry

    NASA Astrophysics Data System (ADS)

    Gudmandsen, Preben

    2003-09-01

    These notes are prepared to give an impression of considerations and activities in Denmark related to ESRO and ESA, roughly in the period 1964 to 1990. In a number of chapters we consider early space-related research in Denmark, the initial phase of the ESRO era and the following period, including the phase of transition from ESRO to ESA when Denmark seriously considered leaving the space co-operation. A chapter gives examples of activities in the ESA era within space science and astronomy, Earth Observation and microgravity, followed by a final one dealing with the national management of optional programmes and the involvement by industry. In drafting the notes we have taken advantage of the work carried out in the Introductory Studies carried out to secure and place in order the archives of the Danish Space Research Advisory Committee. In this connection excerpts of individual documents (mostly minutes of meetings, letters and reports) were taken. To a great extent they form the basis for many of the points made in the notes.

  3. Temporal and spatial variability of the Denmark Strait Overflow

    NASA Astrophysics Data System (ADS)

    Moritz, Martin; Nunes, Nuno; Jochumsen, Kerstin; Quadfasel, Detlef

    2016-04-01

    The Denmark Strait Overflow (DSO) represents about half of the export of dense waters formed in the Nordic Seas to the deep circulation in the North Atlantic. The passage connecting the two is wider than the Rossby radius of deformation, and highly variable meso-scale current fluctuations are observed in the overflow. In the summer of 2014, the mooring array used for monitoring the Denmark Strait Overflow was expanded from two to five moorings in order to better resolve its spatial variability. Continuous measurements of the velocity field were made using four acoustic profilers (ADCP) and one point current meter (RCM). The instruments were deployed along the sill between the deepest point and 33 km westward of it, towards the Greenland shelf. A descriptive analysis of the structure of the velocity field at the Denmark Strait sill is presented, along with its spatial and temporal variability. The fluctuations are dominated by passing meso-scale vortices, pulsating changes in the strength of the overflow and shifts in the location of the Polar Front. These changes and their respective contribution to the variability of the flow field are discussed with relation to the different source water masses for the DSO. The relationship between spatial coherence and temporal variability on daily to monthly time scales is explored, and the influence of meso-scale eddies on daily to weekly transport estimates is quantified. The results of the analysis are used to develop a measurement strategy for unbiased DSO transport estimates.

  4. Epidemiology of Chronic Pain in Denmark and Sweden

    PubMed Central

    Harker, Julie; Reid, Kim J.; Bekkering, Geertruida E.; Kellen, Eliane; Bala, Malgorzata M.; Riemsma, Rob; Worthy, Gill; Misso, Kate; Kleijnen, Jos

    2012-01-01

    Introduction. Estimates on the epidemiology of chronic pain vary widely throughout Europe. It is unclear whether this variation reflects true differences between populations or methodological factors. Information on the epidemiology of chronic pain can support decision makers in allocating adequate health care resources. Methods. In order to obtain epidemiological data on chronic pain in Denmark and Sweden, we conducted a literature review of epidemiological data primarily on chronic noncancer pain, prioritising studies of highest quality, recency, and validity by conducting a systematic search for relevant studies. Following quality assessment, data were summarised and assigned to the research questions. Results. The prevalence of moderate to severe noncancer pain was estimated at 16% in Denmark and 18% in Sweden. Chronic pain impacts negatively on perceived health status, quality of life and is associated with increased cost. Despite using pain medications, a large proportion of chronic pain sufferers have inadequate pain control. There was a lack of high-quality and low-bias studies with clear inclusion criteria. Conclusions. In both Denmark and Sweden, chronic pain is a common health problem which is potentially undertreated and warrants attention of health care workers, policy makers and researchers. Future research should utilise clear reporting guidelines to assist decision and policy makers, in this important area. PMID:22693667

  5. Seismic investigations in downtown Copenhagen, Denmark

    NASA Astrophysics Data System (ADS)

    Martinez, K.; Mendoza, J. A.; Olsen, H.

    2009-12-01

    general velocity layers were observed; 800-1250 m/s, 1250-1700 m/s and a high velocity layer 1700-2500 m/s with localized zones of greater velocities. The variations in the higher velocity layer provide information on limestone properties relevant for tunneling design. The Walkaway-VSP proved to be a useful tool for identifying the velocity fields corresponding to the shallow sediments and the deep sequences of limestone, thus aiding the interpretation of the surface refraction imaging. Data acquisition was planned overnight to reduce external noise impact and optimise production, and urban challenges (e.g. traffic, pipelines) were overcome. Further integrated geophysical interpretation will be done together with hydrogeological analyses, geotechnical evaluations and geological modelling. The authors acknowledge Metroselskabet I/S for permission to present these results, and the Cityringen Joint Venture partners COWI, Arup and Systra.

  6. Spatial emission modelling for residential wood combustion in Denmark

    NASA Astrophysics Data System (ADS)

    Plejdrup, Marlene S.; Nielsen, Ole-Kenneth; Brandt, Jørgen

    2016-11-01

    Residential wood combustion (RWC) is a major contributor to atmospheric pollution especially for particulate matter. Air pollution has significant impact on human health, and it is therefore important to know the human exposure. For this purpose, it is necessary with a detailed high resolution spatial distribution of emissions. In previous studies as well as in the model previously used in Denmark, the spatial resolution is limited, e.g. municipality or county level. Further, in many cases models are mainly relying on population density data as the spatial proxy for distributing the emissions. This paper describes the new Danish model for high resolution spatial distribution of emissions from RWC to air. The new spatial emission model is based on information regarding building type, and primary and supplementary heating installations from the Danish Building and Dwelling Register (BBR), which holds detailed data for all buildings in Denmark. The new model provides a much more accurate distribution of emissions than the previous model used in Denmark, as the resolution has been increased from municipality level to a 1 km × 1 km resolution, and the distribution key has been significantly improved so that it no longer puts an excessive weight on population density. The new model has been verified for the city of Copenhagen, where emissions estimated using both the previous and the new model have been compared to the emissions estimated in a case study. This comparison shows that the new model with the developed weighting factors (76 ton PM2.5) is in good agreement with the case study (95 ton PM2.5), and that the new model has improved the spatial emission distribution significantly compared to the previous model (284 ton PM2.5). Additionally, a sensitivity analysis was done to illustrate the impact of the weighting factors on the result, showing that the new model independently of the weighting factors chosen produce a more accurate result than the old model.

  7. Background nitrogen concentrations in fresh waters in Denmark

    NASA Astrophysics Data System (ADS)

    Windolf, Jørgen; Bøgestrand, Jens; Blicher-Mathiesen, Gitte; Kronvang, Brian

    2013-04-01

    Quantitative information on the background loading of nitrogen is important when establishing the pressure-impact pathway for Danish springs, streams, lakes and estuaries The background nitrogen loading thus determines present day lowest nitrogen loadings without influence from point sources and agriculture but includes present day atmospheric deposition of nitrogen compounds. We have mapped the background concentration of nitrogen in Danish soil water, springs and streams based on monitoring in one soil water station (1990-2010), 11 springs, 7 small streams draining undisturbed catchments (1990-2010) and 19 streams draining small undisturbed catchments (2004-11). The concentration of ammonium-N (NH4+) and organic N was found to be nearly constant within six major landscape types in Denmark, respectively, 0.05 mg ± 0.06 mg N L-1 and 0.53 mg ± 0.29 mg N L-1. On contrary, the concentration of nitrate-nitrite-N (NO3- + NO2-) was found to vary between 0.06-0.83 mg N L-1 within the six landscape types. We have also time series of background total nitrogen concentrations from 7 small undisturbed catchments covering the period 1990-2010. No significant trends have been observed for total nitrogen concentrations from these streams during the period 1990-2010. The measured average nitrate-N concentrations in streams has been modelled against dominant landscape geology and a 5x5 km grid map of Denmark showing background concentrations of nitrate-N and total N has been produced. This map has been used during the implementation of the EU Water Framework Directive as a baseline for estimating background nitrogen losses to surface waters in Denmark. Thus, the average annual background loss of total nitrogen amounts to 13,000 tonnes N or 20% of the total loading of nitrogen from the Danish land to sea during the period 2005-2009.

  8. Some epidemiologic features of canine neosporosis in Denmark.

    PubMed

    Rasmussen, K; Jensen, A L

    1996-04-01

    From a serological survey of 98 dogs, the overall prevalence of subclinical neosporosis among dogs in Denmark was estimated as 15.3%. From a questionnaire completed at the time of blood sampling in 87 dogs, it was found that exposure to cats could be a risk factor for the infection in dogs (odds ratio 3.46; 95% confidence limit 1.1-11.4). Further, it was shown that the antibody response in a pregnant dog increased markedly during gestation, suggesting that the parasite may be reactivated during pregnancy in a manner resembling that of Toxocara canis.

  9. [Fertility treatment in Denmark--development and challenges].

    PubMed

    Ingerslev, Hans Jakob; Humaidan, Peter; Andersen, Anders Nyboe

    2012-10-08

    In Denmark, a total of 31,000 assisted reproductive technology (ART) and intrauterine insemination treatments yearly results in the delivery of around 6,300 children, which represents 9% of the Danish birth cohort. The delivery rate following ART (in vitro fertilization/intracytoplasmatic sperm injection, frozen embryo replacement and oocyte donation) has been stable around 20% per cycle initiated during the last decade, despite the transfer of fewer embryos. The future challenges are the increasing age of women seeking fertility treatment, the development of biomarkers of embryonic implantation potential as well as the improvement of embryo culture, and embryo freezing techniques.

  10. Changing Patterns of Finance in Higher Education. Country Study: Denmark. OECD Educational Monographs.

    ERIC Educational Resources Information Center

    Enslev, Lisbeth; And Others

    A country study on Denmark is presented as part of a series prepared by the Organisation for Economic Cooperation and Development (OCED) Education Committee activity on changing patterns of finance in higher education. In Denmark, postsecondary institutions are the direct responsibility of the state. Some central problems are to strike a balance…

  11. L3 English Acquisition in Denmark and Greenland: Gender-Related Tendencies

    ERIC Educational Resources Information Center

    Spellerberg, Stine Marie

    2011-01-01

    This paper presents findings of gender-related tendencies found in a study of factors influential in third language acquisition of English in Denmark and Greenland. A survey consisting of a questionnaire and an English test was carried out amongst pupils in their last year of compulsory schooling in Copenhagen, Denmark, and Nuuk, Greenland. In…

  12. The Right to Development: Construction of a Non-Agriculturalist Discourse of Rurality in Denmark

    ERIC Educational Resources Information Center

    Svendsen, Gunnar Lind Haase

    2004-01-01

    The paper argues for the existence of two powerful discourses of rurality in Denmark after World War II. The first one is termed the modernist-agriculturalist discourse. Although still influential in the current public debate, in Denmark as well as in other Western European countries, this discourse of rurality had its heyday in the 1960s. It is…

  13. Children's Perspective on Learning: An International Study in Denmark, Estonia, Germany and Sweden

    ERIC Educational Resources Information Center

    Sandberg, Anette; Broström, Stig; Johansson, Inge; Frøkjaer, Thorleif; Kieferle, Christa; Seifert, Anja; Roth, Angela; Tuul, Maire; Ugaste, Aino; Laan, Meeli

    2017-01-01

    This article explores how some children in Denmark, Estonia, Germany and Sweden describe their perspective on learning. The aim of the international study is to gain knowledge of how preschool children in Sweden, Denmark, Estonia and Germany reflect and perceive their learning in preschool and other surrounding social contexts. The results are…

  14. The Non-Shock of PIAAC--Tracing the Discursive Effects of PIAAC in Denmark

    ERIC Educational Resources Information Center

    Cort, Pia; Larson, Anne

    2015-01-01

    The results of the first PIAAC survey were published in October 2013. In the case of Denmark, the survey showed that Denmark is below the OECD average when it comes to reading skills, above average with regards to numeracy and on average with regards to IT skills. In this paper we analyse how the PIAAC results were covered by the media and how…

  15. Comparison of cohort smoking intensities in Denmark and the Netherlands.

    PubMed Central

    Barendregt, Jan J.; Looman, Caspar W. N.; Brønnum-Hansen, Henrik

    2002-01-01

    OBJECTIVE: To assess the usefulness of the general framework of the smoking epidemic. METHODS: We use lung cancer mortality as an indicator for smoking intensity and employ an age-cohort model to accommodate the long-lasting and cumulative effects. RESULTS: Dutch males have higher risks than Danish males, but the risks for the younger cohorts have been declining faster in the Netherlands than in Denmark. Danish women have about twice the risk of Dutch women, and in both countries the risks for the younger cohorts are increasing. The smoking epidemic began at about the same time in Denmark and the Netherlands. Dutch males, however, seem to have smoked more but to have given up smoking more quickly than Danish males. Danish females were quicker to take up smoking than Dutch females. CONCLUSIONS: Within the general framework of the smoking epidemic, differences in timing and levels can produce large differences between countries. For the purposes of assessing smoking-related risks, including projections, the smoking epidemic framework therefore has to be tailored to each study population. PMID:11884970

  16. Bulky waste quantities and treatment methods in Denmark.

    PubMed

    Larsen, Anna W; Petersen, Claus; Christensen, Thomas H

    2012-02-01

    Bulky waste is a significant and increasing waste stream in Denmark. However, only little research has been done on its composition and treatment. In the present study, data about collection methods, waste quantities and treatment methods for bulky waste were obtained from two municipalities. In addition a sorting analysis was conducted on combustible waste, which is a major fraction of bulky waste in Denmark. The generation of bulky waste was found to be 150-250 kg capita(-1) year(-1), and 90% of the waste was collected at recycling centres; the rest through kerbside collection. Twelve main fractions were identified of which ten were recyclable and constituted 50-60% of the total quantity. The others were combustible waste for incineration (30-40%) and non-combustible waste for landfilling (10%). The largest fractions by mass were combustible waste, bricks and tile, concrete, non-combustible waste, wood, and metal scrap, which together made up more than 90% of the total waste amounts. The amount of combustible waste could be significantly reduced through better sorting. Many of the waste fractions consisted of composite products that underwent thorough separation before being recycled. The recyclable materials were in many cases exported to other countries which made it difficult to track their destination and further treatment.

  17. Helminths of red foxes (Vulpes vulpes) in Denmark.

    PubMed

    Saeed, I; Maddox-Hyttel, C; Monrad, J; Kapel, C M O

    2006-06-30

    An epidemiological study of helminths in 1040 red foxes collected from various localities in Denmark during 1997-2002, revealed 21 helminth species at autopsy, including nine nematode species: Capillaria plica (prevalence 80.5%), Capillaria aerophila (74.1%), Crenosoma vulpis (17.4%), Angiostrongylus vasorum (48.6% from Northern Zealand (endemic area)), Toxocara canis (59.4%), Toxascaris leonina (0.6%), Uncinaria stenocephala (68.6%), Ancylostoma caninum (0.6%), and Trichuris vulpis (0.5%); seven cestodes: Mesocestoides sp. (35.6%), a number of Taeniid species (Taenia pisiformis, T. hydatigena, T. taeniaeformis, T. crassiceps, and unidentified Taenia spp.) (22.8%), and Echinococcus multilocularis (0.3%); four trematodes: Alaria alata (15.4%), Cryptocotyle lingua (23.8%), Pseudamphystomum truncatum (3.6% from Northern Zealand), and Echinochasmus perfoliatus (2.4% from Northern Zealand); one acanthocephalan: Polymorphus sp. (1.2%). Significant difference in prevalence was found for T. canis and A. vasorum according to host sex, and for T. canis, U. stenocephala, Mesocestoides sp., Taenia spp., A. alata, A. vasorum, and Capillaria spp. according to age groups (adult, young or cub). Prevalence and average worm intensity for each helminth species varied considerably according to geographical locality, season, and year. Aggregated distribution was found for several helminth species. The two species E. multilocularis and E. perfoliatus are first records for Denmark.

  18. Epidemiology of pertussis in Denmark, 1995 to 2013

    PubMed Central

    Dalby, Tine; Andersen, Peter Henrik; Hoffmann, Steen

    2016-01-01

    We describe incidence and age distribution of laboratory-confirmed pertussis in Denmark from 1995 to 2013. Notification has been mandatory since 2007. Since 1997, an acellular monocomponent vaccine has been used. The latest epidemic occurred in 2002 with an incidence of 36 per 100,000; since 1995, only six infant deaths have been recorded. The inter-epidemic incidence lies below 10 per 100,000. In 1995, the mean age of confirmed cases was 9.2 years (95% confidence interval (CI): 7.9–10.5; median: 5.1), this gradually increased to 23.9 years in 2013 (95% CI: 22.0–25.8; median: 15.7). In 1995, 14% of laboratory-confirmed cases were 20 years and older, 43% in 2013. In the study period, the highest incidence among children was among those younger than one year with incidences between 84 and 331 per 100,000 in inter-epidemic periods (mean: 161/100,000) and 435 for the epidemic in 2002. After introduction of a preschool booster in 2003, the highest incidence among children one year and older changed gradually from three to five-year-olds in 2003 to 12 to 14-year-olds in 2013. In 2013, PCR was the primary method used for laboratory-diagnosis of pertussis in Denmark, while serology was the method with the highest percentage of positive results. PMID:27632433

  19. Rates and characteristics of sleep paralysis in the general population of Denmark and Egypt.

    PubMed

    Jalal, Baland; Hinton, Devon E

    2013-09-01

    In the current research we report data from two studies that examined rates and characteristics of sleep paralysis (SP) in the general population of Denmark and Egypt. In Study I, individuals from Denmark and Egypt did not differ in age whereas there were more males in the Egyptian sample (47 vs. 64 %); in Study II, individuals from Denmark and Egypt were comparable in terms of age and gender distribution. In Study I we found that significantly fewer individuals had experienced SP in Denmark [25 % (56/223)] than in Egypt [44 % (207/470)] p < .001. In Study II we found that individuals who had experienced at least one lifetime episode of SP from Denmark (n = 58) as compared to those from Egypt (n = 143) reported significantly fewer SP episodes in a lifetime relative to SP experiencers from Egypt (M = 6.0 vs. M = 19.4, p < .001). SP in the Egyptian sample was characterized by high rates of SP (as compared to in Denmark), frequent occurrences (three times that in the Denmark sample), prolonged immobility during SP, and great fear of dying from the experience. In addition, in Egypt, believing SP to be precipitated by the supernatural was associated with fear of the experience and longer SP immobility. Findings are discussed in the context of cultural elaboration and salience theories of SP.

  20. Contents of capsaicinoids in chillies grown in Denmark.

    PubMed

    Duelund, Lars; Mouritsen, Ole G

    2017-04-15

    We have studied 15 different cultivars of chillies (Capsicum var.) grown in temperate climate Denmark and determined the contents of the four major capsaicinoids: capsaicin, dihydrocapsaicin, nordihydrocapsaicin, and homocapsaicin. From these contents we have, as commonly done for chillies, calculated the so-called pungency in Scoville heat units in order to compare with previous studies from other climatical zones. For three of the investigated cultivars, Serrano, Habanero and BIH Jolokia, for which reliable pungencies has previously been reported, we have found pungencies of 34,000±1400, 247,000±24,000 and 665,000±4000, respectively, which are all in the same ranges as found earlier for chillies grown in more traditional chilli growing areas. Furthermore we have found that the relative distribution of the four capsaicinoids in the 15 different cultivars is highly variable, with the content of capsaicin ranging from 31% to 71% of the total capsaicinoid content.

  1. Sparteine oxidation polymorphism in Greenlanders living in Denmark.

    PubMed Central

    Brøsen, K

    1986-01-01

    Sparteine oxidation appeared to be polymorphic in 185 healthy Greenlanders living in Denmark. Six subjects (3.2%) were phenotyped as poor metabolizers (PM) and 179 subjects as extensive metabolizers (EM). The metabolic ratio (MR) between sparteine and 2- + 5-dehydrosparteine in a 12 h urine sample ranged from 0.06-3.12 in EM and from 30-480 in PM. The excretion of dehydrosparteines accounted for less than 2.2% of the dose in PM and ranged from 5.6%-63% in EM. The urinary recovery (% of dose) of sparteine, 2-dehydrosparteine and total sparteine + dehydrosparteines was lower in Greenlander EM than in Danish EM (Brøsen et al., 1985). Incomplete urine collection in a substantial proportion of the Greenlanders could explain these discrepancies. PMID:3768256

  2. Incidence and Determinants of Ventilation Tubes in Denmark

    PubMed Central

    Pedersen, Tine Marie; Mora-Jensen, Anna-Rosa Cecilie; Waage, Johannes; Bisgaard, Hans; Stokholm, Jakob

    2016-01-01

    Background and objectives Many children are treated for recurrent acute otitis media and middle ear effusion with ventilation tubes (VT). The objectives are to describe the incidence of VT in Denmark during 1997–2011 from national register data, furthermore, to analyze the determinants for VT in the Copenhagen Prospective Studies on Asthma in Childhood2010 (COPSAC2010) birth cohort. Methods The incidence of VT in all children under 16 years from 1997–2011 were calculated in the Danish national registries. Determinants of VT were studied in the COPSAC2010 birth cohort of 700 children. Results Nationwide the prevalence of VT was 24% in children aged 0 to 3 three years, with a significant increase over the study period. For all children 0–15 years, the incidence of VT was 35/1,000. In the VT population, 57% was male and 43% females. In the COPSAC2010 birth cohort, the prevalence of VT during the first 3 years of life was 29%. Determinants of VT were: maternal history of middle ear disease; aHR 2.07, 95% CI [1.45–2.96] and siblings history of middle ear disease; aHR 3.02, [2.11–4.32]. Paternal history of middle ear disease, presence of older siblings in the home and diagnosis of persistent wheeze were significant in the univariate analysis but the association did not persist after adjustment. Conclusion The incidence of VT is still increasing in the youngest age group in Denmark, demonstrating the highest incidence recorded in the world. Family history of middle ear disease and older siblings are the main determinants for VT. PMID:27875554

  3. Waste collection systems for recyclables: An environmental and economic assessment for the municipality of Aarhus (Denmark)

    SciTech Connect

    Larsen, A.W.; Merrild, H.; Moller, J.; Christensen, T.H.

    2010-05-15

    Recycling of paper and glass from household waste is an integrated part of waste management in Denmark, however, increased recycling is a legislative target. The questions are: how much more can the recycling rate be increased through improvements of collection schemes when organisational and technical limitations are respected, and what will the environmental and economic consequences be? This was investigated in a case study of a municipal waste management system. Five scenarios with alternative collection systems for recyclables (paper, glass, metal and plastic packaging) were assessed by means of a life cycle assessment and an assessment of the municipality's costs. Kerbside collection would provide the highest recycling rate, 31% compared to 25% in the baseline scenario, but bring schemes with drop-off containers would also be a reasonable solution. Collection of recyclables at recycling centres was not recommendable because the recycling rate would decrease to 20%. In general, the results showed that enhancing recycling and avoiding incineration was recommendable because the environmental performance was improved in several impact categories. The municipal costs for collection and treatment of waste were reduced with increasing recycling, mainly because the high cost for incineration was avoided. However, solutions for mitigation of air pollution caused by increased collection and transport should be sought.

  4. Seasonal Hydrometeorological Ensemble Prediction System; Forecast of Irrigation Potentials in Denmark

    NASA Astrophysics Data System (ADS)

    Lucatero, D.; Jensen, K. H.; Madsen, H.; Refsgaard, J. C.; Kidmose, J.

    2015-12-01

    The European Center for Medium Weather Forecast seasonal ensemble prediction system (ECMWF-SEPS) of weather variables such as precipitation, temperature and evapotranspiration is used as input to an integrated surface-subsurface hydrological model based on the MIKE SHE system to generate probabilistic forecasts of the irrigation requirements in the Skjern river catchment in Denmark. We demonstrate the usability of the ECMWF-SEPS and discuss the challenges and areas of opportunities when issuing forecasts generated with this methodology. A simple bias-correction and downscaling technique, namely linear scaling, is applied to the raw inputs to remove the bias intrinsic in ensemble prediction systems and to downscale the data to a scale appropriate for hydrological modelling. The forecasts of the meteorological variables are analysed for accuracy and reliability by comparing them to meteorological observations. Additionally, weather ensembles will be generated using the nearest-neighbour resampling technique with the purpose of exploring additional possibilities of hydrometeorological system input for complementing situations where the SEPS is lacking skill.

  5. Waste collection systems for recyclables: an environmental and economic assessment for the municipality of Aarhus (Denmark).

    PubMed

    Larsen, A W; Merrild, H; Møller, J; Christensen, T H

    2010-05-01

    Recycling of paper and glass from household waste is an integrated part of waste management in Denmark, however, increased recycling is a legislative target. The questions are: how much more can the recycling rate be increased through improvements of collection schemes when organisational and technical limitations are respected, and what will the environmental and economic consequences be? This was investigated in a case study of a municipal waste management system. Five scenarios with alternative collection systems for recyclables (paper, glass, metal and plastic packaging) were assessed by means of a life cycle assessment and an assessment of the municipality's costs. Kerbside collection would provide the highest recycling rate, 31% compared to 25% in the baseline scenario, but bring schemes with drop-off containers would also be a reasonable solution. Collection of recyclables at recycling centres was not recommendable because the recycling rate would decrease to 20%. In general, the results showed that enhancing recycling and avoiding incineration was recommendable because the environmental performance was improved in several impact categories. The municipal costs for collection and treatment of waste were reduced with increasing recycling, mainly because the high cost for incineration was avoided. However, solutions for mitigation of air pollution caused by increased collection and transport should be sought.

  6. Elevated Ozone Levels in Denmark: Analysis Employing Trajectory and Chemical Transport Modelling

    NASA Astrophysics Data System (ADS)

    Mahura, A.; Gross, A.; Petrova, I.

    2009-09-01

    In our study, among 9 Danish measurement sites, 3 sites having long-term ozone measurement (with a time resolution of 1 hour and starting in early 1990s) records were selected - Ulborg (DK31; 56.28°N, 8.43°E) and Frederiksborg (DK32; 55.97°N, 12.33°E) and Lille Valby (DK41; 55.69°N, 12.13°E) located on Jutland Peninsula and Zealand Island of Denmark, respectively. After pre-screening of the time series (covering almost 15 year period and including almost 543 thousand valid observations), the measurements with high ozone level (using threshold as 150 µg/m3) were selected accounting in total for 508 cases for these 3 locations. Among these, 42 (for DK41) and 59 (for DK31 and DK32) cases showed very high ozone concentrations (i.e. above 180 µg/m3). For all these cases, at first, the trajectory modelling approach was applied in order to estimate atmospheric transport pathway of air mass arrival at the measurement sites and potential source regions from where the elevated ozone level can be associated. In our study the Hybrid Single Particle Lagrangian Integrated Trajectory Model (HYSPLIT) model using REANALYSIS meteorological dataset (global, 1948-present) was run to calculate a set of backward trajectories (in total 508, with duration of 5 day backward in time and arriving at altitude of 100 m) and divide into groups with respect to potential source regions and dominating atmospheric transport pathways using cluster analysis technique. Several relatively long-term episodes with continuous elevated ozone were identified in the analyzed time series; in particular, for DK31 - 7 episodes (having longest duration and observed in Jun 1996 and Jun 2000), DK32 - 5 (Jul 1992 and Jun 2000), and DK41 - 4 (Jul 1992 and Jun 2000). For selected episodes the off-line Eulerian Chemistry-Aerosol-Cloud (CAC) model was run over the European domain. As meteorological driver, the High Resolution Limited Area Model (HIRLAM) generated output with 3D meteorological fields was used

  7. [Cholera in Europe and Denmark in the 19th century].

    PubMed

    Bonderup, G

    1996-01-01

    There are several reasons for dealing with cholera in the 19th century: it acted as a spotlight throwing into sharp relief the darkest corners of society that are seldom mentioned in the sources. We learn about everyday life in large parts of the population, especially the poor. The fight against the disease also reveals how a society worked socially and politically. When cholera arrived in Europe -- the first time was in the 1830's and several times after that--the population reacted very violently, often by lynching doctors, while the authorities more or less let matters take their course. That is why international researchers have come to see cholera as a catalyst for the constantly latent social unrest following in the train of wars and revolutions. During my research on cholera in Denmark it became clear to me that matters were different here. There were no riots, nor any signs of social unrest--neither before nor after the outbreak of cholera. On the contrary, the authorities and the population joined forces against the epidemic. There was an atmosphere of mutual trust, and almost everybody turned out to be worthy of such trust. That points to a balanced society based on consensus, so cholera also functions as a detector of the fundamental structure of a society.

  8. Cumulative dietary exposure of the population of Denmark to pesticides.

    PubMed

    Jensen, Bodil Hamborg; Petersen, Annette; Nielsen, Elsa; Christensen, Tue; Poulsen, Mette Erecius; Andersen, Jens Hinge

    2015-09-01

    We used the Hazard Index (HI) method to carry out a cumulative risk assessment after chronic dietary exposure to all monitored pesticides in fruit, vegetables and cereals for various consumer groups in Denmark. Residue data for all the pesticides were obtained from the Danish monitoring programme during the period 2004-2011. Food consumption data were obtained from DANSDA (the DAnish National Survey of Diet and physical Activity) for the period 2005-2008. The calculations were made using three different models to cope with residues below the limit of reporting (LOR). We concluded that a model that included processing factors and set non-detects to ½ LOR, but limited the correction (Model 3), gave the most realistic exposure estimate. With Model 3 the HI was calculated to be 0.44 for children and 0.18 for adults, indicating that there is no risk of adverse health effects following chronic cumulative exposure to the pesticides found in fruit, vegetables and cereals on the Danish market. The HI was below 1 even for consumers who eat more than 550 g of fruit and vegetables per day, corresponding to 1/3 of the population. Choosing Danish-produced commodities whenever possible could reduce the HI by a factor of 2.

  9. End-cretaceous brachiopod extinctions in the chalk of denmark.

    PubMed

    Surlyk, F; Johansen, M B

    1984-03-16

    The results of a detailed study of the brachiopods of the most complete Cretaceous-Tertiary boundary in Denmark, Nye Klslashed circlev, show an extinction pattern for this marine invertebrate group compatible with that reported for pelagic foraminifera and coccoliths and with the impact scenario. The extinction is abrupt, coinciding with the Maastrichtian-Danian boundary. There is no warning in the form of decreasing density, decreasing diversity, or early extinction of specialized groups. The basal few meters of the Danian are almost devoid of brachiopods, and a Danian brachiopod fauna starts almost as abruptly as the Maastrichtian fauna disappeared. The new fauna is similar to the Maastrichtian as regards density and diversity, and at maximum six species are common to both stages. The northwest European Masstrichtian chalk is composed mainly of the remains of coccoliths and pelagic foraminifera. The mass extinction of these groups led to a total cessation of chalk production. The chalk is overlain by a thin clay bed deposited partly under anoxic conditions. This combination of anoxia and clay deposition coupled with a cessation of productivity led to the extinction of specialized groups such as the chalk brachiopods. The surviving species included forms that could survive in well-aerated shallow marine waters on substrates other than chalk.

  10. End-Cretaceous Brachiopod Extinctions in the Chalk of Denmark

    NASA Astrophysics Data System (ADS)

    Surlyk, Finn; Bagge Johansen, Marianne

    1984-03-01

    The results of a detailed study of the brachiopods of the most complete Cretaceous-Tertiary boundary in Denmark, Nye Klov, show an extinction pattern for this marine invertebrate group compatible with that reported for pelagic foraminifera and coccoliths and with the impact scenario. The extinction is abrupt, coinciding with the Maastrichtian-Danian boundary. There is no warning in the form of decreasing density, decreasing diversity, or early extinction of specialized groups. The basal few meters of the Danian are almost devoid of brachiopods, and a Danian brachiopod fauna starts almost as abruptly as the Maastrichtian fauna disappeared. The new fauna is similar to the Maastrichtian as regards density and diversity, and at maximum six species are common to both stages. The northwest European Maastrichtian chalk is composed mainly of the remains of coccoliths and pelagic foraminifera. The mass extinction of these groups led to a total cessation of chalk production. The chalk is overlain by a thin clay bed deposited partly under anoxic conditions. This combination of anoxia and clay deposition coupled with a cessation of productivity led to the extinction of specialized groups such as the chalk brachiopods. The surviving species included forms that could survive in well-aerated shallow marine waters on substrates other than chalk.

  11. Occupational exposures to styrene in Denmark 1955-88.

    PubMed

    Jensen, A A; Breum, N O; Bacher, J; Lynge, E

    1990-01-01

    An assessment of the occupational exposure to styrene and associated chemicals in Denmark was carried out by retrieving all measurements from the archives of the Danish National Institute of Occupational Health. A total of 2,528 air samples containing styrene had been collected from 256 workplaces during the years 1955-88 and analyzed by the chemical laboratory at the Institute. The mean for all samples was 265 mg/m3. The concentration decreased from 714 mg/m3 in the early period (1955-70) to 172 mg/m3 in the late period (1981-88). Spraying and unspecified lay-up and production of boats, carriages, and stationary containers were associated with the highest concentration. A total of 34 chemicals were measured. The most frequent co-contaminant to styrene was acetone, which was measured in 2,263 samples with a mean concentration of 131 mg/m3. Dichloromethane was measured in 208 samples with a mean concentration of 51 mg/m3, xylene in 148 samples with a mean concentration of 49 mg/m3, and toluene in 116 samples with a mean concentration of 113 mg/m3. The study was undertaken to analyze historical styrene concentrations in air to aid in the selection of industrial cohorts to be included in epidemiologic studies.

  12. Seasonal generation and composition of garden waste in Aarhus (Denmark).

    PubMed

    Boldrin, Alessio; Christensen, Thomas H

    2010-04-01

    Garden waste generation and composition were studied in Aarhus, Denmark. The amount of garden waste generated varied seasonally, from 2.5kgperson(-1)month(-1) in winter to 19.4kgperson(-1)month(-1) in summer. Seasonal fractional composition and chemical characterization of garden waste were determined by sorting and sampling garden waste eight times during 1year. On a yearly basis, the major fraction of garden waste was "small stuff" (flowers, grass clippings, hedge cuttings and soil) making up more than 90% (wet waste distribution) during the summer. The woody fractions (branches, wood) are more significant during the winter. Seasonal trends in waste chemical composition were recorded and an average annual composition of garden waste was calculated, considering the varying monthly generation and material fraction composition: the wet garden waste contained 40% water, 30% organic matter (VS) and 30% ash. The ash content suggests that the garden waste contains a significant amount of soil. This is in particular the case during summer. Of nutrients, the garden waste contained in average on a dry matter basis 0.6% N, 0.1% P, and 1.0% K. However, the contents varied significantly among the fractions and during the year. The content of trace elements (Cd, Cr, Cu, Hg, Ni, Pb, and Zn) was low.

  13. Heavy metal content of combustible municipal solid waste in Denmark.

    PubMed

    Riber, Christian; Fredriksen, Gry S; Christensen, Thomas H

    2005-04-01

    Data on the heavy metal composition of outlets from Danish incinerators was used to estimate the concentration of Zn, Cu, Pb, Cr, Ni, Cd, As and Hg in combustible waste (wet as received) at 14 Danish incinerators, representing about 80% of the waste incinerated in Denmark. Zn (1020 mg kg(-1)), Cu (620 mg kg(-1)) and Pb (370 mg kg(-1)) showed the highest concentration, whereas Hg (0.6 mg kg(-1)) showed the lowest concentration. The variation among the incinerators was in most cases within a factor of two to three, except for Cr that in two cases showed unexplained high concentrations. The fact that the data represent many incinerators and, in several cases, observations from a period of 4 to 5 years provides a good statistical basis for evaluating the content of heavy metals in combustible Danish waste. Such data may be used for identifying incinerators receiving waste with high concentrations of heavy metals suggesting the introduction of source control, or, if repeated in time, the data must also be used for monitoring the impacts of national regulation controlling heavy metals. It is recommended that future investigations consider the use of sample digestion methods that ensure complete digestion in order to use the data for determining the total heavy metal content of waste.

  14. Human risk from thermotolerant Campylobacter on broiler meat in Denmark.

    PubMed

    Boysen, Louise; Nauta, Maarten; Duarte, Ana Sofia Ribeiro; Rosenquist, Hanne

    2013-03-15

    This paper describes a new approach by which changes over time in the relative risk of human campylobacteriosis from broiler meat are evaluated through quantitative microbiological risk assessment modelling. Danish surveillance data collected at retail from 2001 to 2010 on numbers of thermotolerant Campylobacter spp. on Danish produced and imported chilled and frozen broiler meat were the basis for the investigation. The aim was to explore if the risk from the different meat categories had changed over time as a consequence of implemented intervention strategies. The results showed a slight decrease from 2005 to 2008 in the human risk from Danish produced broiler meat, and a decrease from 2005 to 2010 in the risk from imported chilled meat. This risk reduction coincides with control measures implemented to reduce Campylobacter in Danish and imported chilled broiler meat. The human risk of campylobacteriosis from Danish frozen meat increased but remained lower compared to chilled meat. In total, the relative risk from broiler meat available for sale in Denmark increased from 2001 to 2005 after which the risk decreased to a level similar to the period 2001-2002. The use of QMRA in the evaluation of intervention strategies based on monitoring data provided an added value, compared to the traditional approach of only using changes in prevalence. The estimated human health risk is a function of prevalence and the distribution of concentrations, and therefore takes best usage of the available data, while providing the most relevant outcome for food safety risk managers.

  15. New national emission inventory for navigation in Denmark

    NASA Astrophysics Data System (ADS)

    Winther, Morten

    This article explains the new emission inventory for navigation in Denmark, covering national sea transport, fisheries and international sea transport. For national sea transport, the new Danish inventory distinguishes between regional ferries, local ferries and other national sea transport. Detailed traffic and technical data lie behind the fleet activity-based fuel consumption and emission calculations for regional ferries. For local ferries and other national sea transport, the new inventory is partly fleet activity based; fuel consumption estimates are calculated for single years, and full fuel consumption coverage is established in a time series by means of appropriate assumptions. For fisheries and international sea transport, the new inventory remains fuel based, using fuel sales data from the Danish Energy Authority (DEA). The new Danish inventory uses specific fuel consumption (sfc) and NO x emission factors as a function of engine type and production year. These factors, which are used directly for regional ferries and, for the remaining navigation categories, are derived by means of appropriate assumptions, serve as a major inventory improvement, necessary for making proper emission trend assessments. International sea transport is the most important fuel consumption and emission source for navigation, and the contributions are large even compared with the overall Danish totals. If the contributions from international sea transport were included in the Danish all-sector totals, the extra contributions in 2005 from fuel consumption (and CO 2), NO x and SO 2 would be 5%, 34% and 167%, respectively. The 1990-2005 changes in fuel consumption as well as NO x and SO 2 emissions for national sea transport (-45, -45, -81), fisheries (-18, 6, -18) and international sea transport (-14, 1, -14) reflect changes in fleet activity/fuel consumption and emission factors. The 2006-2020 emission forecasts demonstrate a need for stricter fuel quality and NO x emission

  16. Occupational and recreational physical activity and Parkinson's disease in Denmark.

    PubMed

    Shih, I-Fan; Starhof, Charlotte; Lassen, Christina Funch; Hansen, Johnni; Liew, Zeyan; Ritz, Beate

    2017-03-20

    Objectives This study aimed to examine whether occupational and physical activity (PA) at different ages contribute to Parkinson's disease (PD) risk in a large population-based case-control study in Denmark. Methods We identified 1828 PD patients from the Danish National Hospital Register and recruited 1909 gender and year of birth matched controls from the Danish Central Population Register. Occupational and leisure-time PA were determined from a job exposure matrix based on occupational history and self-reported leisure-time information. Results No association was found for occupational PA alone in men, but higher leisure-time PA (≥5 hours/week of strenuous activities) in young adulthood (15-25 years) was associated with a lower PD risk (adjusted odds ratio (OR adj) 0.75, 95% confidence interval (95% CI) 0.62-0.90); men who engaged in high occupational and high leisure-time PA in young adulthood had the lowest PD risk (OR adj0.58, 95% CI 0.41-0.81). Among women, inverse associations were found for occupation PA before age 50 (highest vs lowest, OR adj0.75, 95% CI 0.55-1.06) and strenuous leisure-time PA after age 50 (OR adj0.65, 95% CI 0.87-0.99); no clear pattern was seen for leisure and occupational PA combined. Conclusions We observed gender-specific inverse associations between occupational and leisure-time PA and PD risk; however, we cannot preclude reverse causation especially in older ages since PD has a long prodromal stage that might lead to a reduction of PA years before motor symptom onset and PD diagnosis.

  17. Atmospheric ammonia exchange on a heathland in Denmark

    NASA Astrophysics Data System (ADS)

    Hansen, Birgitte; Nørnberg, Per; Rasmussen, Keld Rømer

    Passive flux samplers were used to determine the ammonia exchange on an inland heath in Denmark over the last 2 years. The samplers measured the horizontal ammonia flux directly. Data were sampled continuously for periods of 1-4 weeks. The micro-meteorological gradient method was used with passive flux samplers and cup anemometers at different heights above the vegetation in order to calculate the vertical fluxes of ammonia. First a fixed sampler system was used with tubes mounted in four orthogonal horizontal directions. This system has been successfully applied to measure the emission from fertilized crops. Adapting this type of sampler to measure the deposition to heathlands did not prove to be straightforward. The precision of the calculated ammonia concentrations was too poor to give an acceptable accuracy for the concentration gradient. The problems were (a) driving rain which entered the tubes, (b) too few measuring points in each concentration profile, and (c) too long sampling periods to allow for the low-concentration levels above the heath area and the detection limits. Therefore, a passive flux sampler mounted on a wind vane and fitted with a rain shelter was developed. Results from the first 5 weekly periods are very promising, yielding accurate concentration gradients. The advantages of the passive flux samplers on the wind vane are (a) the minimum measuring period can be approximately halved compared to the fixed samplers, (b) some of the directional correction terms used with the fixed passive flux samplers are dispensed with, and (c) the field and laboratory work is minimized.

  18. Factors contributing to young moped rider accidents in Denmark.

    PubMed

    Møller, Mette; Haustein, Sonja

    2016-02-01

    Young road users still constitute a high-risk group with regard to road traffic accidents. The crash rate of a moped is four times greater than that of a motorcycle, and the likelihood of being injured in a road traffic accident is 10-20 times higher among moped riders compared to car drivers. Nevertheless, research on the behaviour and accident involvement of young moped riders remains sparse. Based on analysis of 128 accident protocols, the purpose of this study was to increase knowledge about moped accidents. The study was performed in Denmark involving riders aged 16 or 17. A distinction was made between accident factors related to (1) the road and its surroundings, (2) the vehicle, and (3) the reported behaviour and condition of the road user. Thirteen accident factors were identified with the majority concerning the reported behaviour and condition of the road user. The average number of accident factors assigned per accident was 2.7. Riding speed was assigned in 45% of the accidents which made it the most frequently assigned factor on the part of the moped rider followed by attention errors (42%), a tuned up moped (29%) and position on the road (14%). For the other parties involved, attention error (52%) was the most frequently assigned accident factor. The majority (78%) of the accidents involved road rule breaching on the part of the moped rider. The results indicate that preventive measures should aim to eliminate violations and increase anticipatory skills among moped riders and awareness of mopeds among other road users. Due to their young age the effect of such measures could be enhanced by infrastructural measures facilitating safe interaction between mopeds and other road users.

  19. Impacts of 21st century climate changes on flora and vegetation in Denmark

    NASA Astrophysics Data System (ADS)

    Skov, Flemming; Nygaard, Bettina; Wind, Peter; Borchsenius, Finn; Normand, Signe; Balslev, Henrik; Fløjgaard, Camilla; Svenning, Jens-Christian

    2009-11-01

    In this paper we examined the potential impacts of predicted climatic changes on the flora and vegetation in Denmark using data from a digital database on the natural vegetation of Europe. Climate scenarios A2 and B2 were used to find regions with present climatic conditions similar to Denmark's climate in the year 2100. The potential natural vegetation of Denmark today is predominantly deciduous forest that would cover more than 90% of the landscape. Swamps, bogs, and wet forest would be found under moist or wet conditions. Dwarf shrub heaths would be naturally occurring on poor soils along the coast together with dune systems and salt-marsh vegetation. When comparing the natural vegetation of Denmark to the vegetation of five future-climate analogue areas, the most obvious trend is a shift from deciduous to thermophilous broadleaved forest currently found in Southern and Eastern Europe. A total of 983 taxa were recorded for this study of which 539 were found in Denmark. The Sørensen index was used to measure the floristic similarity between Denmark and the five subregions. Deciduous forest, dwarf shrub heath, and coastal vegetation were treated in more detail, focusing on potential new immigrant species to Denmark. Finally, implications for management were discussed. The floristic similarity between Denmark and regions in Europe with a climate similar to what is expected for Denmark in year 2100 was found to vary between 48-78%, decreasing from North to South. Hence, it seems inevitable that climate changes of the magnitudes foreseen will alter the distribution of individual species and the composition of natural vegetation units. Changes, however, will not be immediate. Historic evidence shows a considerable lag in response to climatic change under natural conditions, but little is known about the effects of human land-use and pollution on this process. Facing such uncertainties we suggested that a dynamic strategy based on modeling, monitoring and adaptive

  20. Broad-scale patterns of abundance of non-indigenous soft-bottom invertebrates in Denmark

    NASA Astrophysics Data System (ADS)

    Thomsen, Mads S.; Wernberg, Thomas; Silliman, Brian R.; Josefson, Alf B.

    2009-06-01

    Quantifying the broad-scale distribution and abundance of non-indigenous species (NIS) is necessary to provide accurate estimations on impacts of invasions, to prioritize research, and to guide national management. Sediment grab-sampling is a standardized method for monitoring marine benthos. In Denmark, ~45,000 grab-samples were collected from 1970 to 2005. Using these samples, we compared densities of NIS and native species among 27 broad spatio-temporal groupings. Eight known NIS and one ‘cryptogenic species’ (the polychaete Neanthes succinea) were found in the samples. Most were present in low abundance, but the bivalve Mya arenaria, likely introduced by the vikings from North America, was particularly abundant. M. arenaria was found in ca. 20% of all samples and was among the 10 most common species in all of Denmark. M. arenaria’s high abundance, high filtration capacity and importance in food-web interactions, suggest that this species has dramatically impacted shallow coastal ecosystems in Denmark. The polychaete Marenzelleria viridis, the gastropod Potamopyrgus antipodarum and N. succinea were also widespread and abundant, and they too are likely to have had broad-scale impacts. In conclusion, 28% of grab-samples collected in Denmark over 35 years were affected by some degree of NIS or cryptogenic species, suggesting that centuries of human-mediated transfer of organisms has had a profound impact on the ecology of soft-bottom systems in Denmark.

  1. Short communication: Improving accuracy of Jersey genomic evaluations in the United States and Denmark by sharing reference population bulls

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The effect on prediction accuracy for Jersey genomic evaluations in Denmark and the United States from using larger reference populations was assessed. Each country contributed genotypes from 1,157 Jersey bulls to the reference population of the other. Eight of 9 traits analyzed by Denmark (milk, fa...

  2. Isomers of fluoroamphetamines detected in forensic cases in Denmark.

    PubMed

    Johansen, Sys Stybe; Hansen, Tina Maria

    2012-07-01

    A study was performed on the detection, separation and quantification of isomers from the new designer drugs named fluoroamphetamines (FAs) in forensic cases in eastern Denmark. The drugs were detected in whole blood extracts by ultraperformance liquid chromatography with time of flight mass spectrometer (UPLC-TOF-MS) and thereafter verified and quantified by UPLC tandem mass spectrometer (MS/MS). The quantitative method involved liquid–liquid extraction of FAs from whole blood, evaporation of organic solvent, and reconstitution with a mobile phase mixture. Identification of the FAs was achieved by the retention time, multiple reaction monitoring (MRM) traces [154 > 109 (quantifier); 154 > 137], and ion ratio of the two transitions. For all FAs, LOQ was 0.002 mg/kg with linear ranges from 0.002 to 1.0 mg/kg whole blood. Since 2008, a total of 15 forensic investigations, mainly driving under the influence of drugs (DUID) cases, involving 4-fluoroamphetamine (4-FA) have been observed with whole blood concentrations ranging from 0.006 to 0.58 mg/kg. One autopsy case involved 4-FA; however, it was determined to be a combined intoxication. In 2010, ortho-fluoroamphetamine (2-FA) was discovered in forensic samples by the same UPLC/MS/MS method and MRM functions because of variation in retention time and ion ratio. Up to now, three eastern Danish DUID cases have involved 2-FA. The whole blood concentrations of 2-FA were 0.028, 0.041 and 0.37 mg/kg, respectively. Thirteen cases with 4-FA and the three cases with 2-FA also contained amphetamine, but no correlation was observed between the amount of FA and amphetamine. So far, 3-FA has not been observed in any cases, and although it co-elutes with 4-FA, 3-FA will be identified by its variation in ion ratio. To our knowledge, this study has confirmed 2-FA in blood from DUID cases for the first time, and provides typical whole blood concentrations of FAs in forensic cases.

  3. [The use of foeticide in late termination of pregnancies in Denmark].

    PubMed

    Vinggaard Christensen, Anne; Petersson, Birgit H

    2013-01-28

    As a result of prenatal screening the number of late terminations of pregnancy is increasing in Denmark. The fact that the foetus sometimes shows signs of life after the termination is a large concern for health-care staff and parents. In other countries foeticide is performed intrauterinely to ensure that the foetus is dead before the delivery. In Denmark this method is legally used in foetal reduction, but not in late termination of pregnancy. In the light of international literature on the subject, perspectives on foeticide in late termination of pregnancy are explored.

  4. Estimates of entrainment in the Denmark Strait overflow plume from CTD/LADCP data

    NASA Astrophysics Data System (ADS)

    Zhurbas, V. M.; Paka, V. T.; Rudels, B.; Quadfasel, D.

    2016-03-01

    The data of the CTD survey conducted in the Denmark Strait and Irminger Sea in May-June 2009 are used to calculate the vertical profiles of the turbulent overturning scale, which are then used to estimate the dissipation and entrainment rates in the overflow plume. The resulting estimates of the entrainment rate varied widely from 2 × 10-7 to 7 × 10-3 m/s. It is shown that such a wide range of entrainment rates is caused by the intermittency of turbulence. Large turbulent overturning at the interface of the Denmark Strait overflow plume is detected on the vertical temperature, salinity, and potential density profiles.

  5. Comparative Study of Teaching Content in Teacher Education Programmes in Canada, Denmark, Finland and Singapore

    ERIC Educational Resources Information Center

    Rasmussen, Jens; Bayer, Martin

    2014-01-01

    This article presents the results of a comparative study of the content in selected teacher education programmes for primary and lower secondary teachers in Canada, Denmark, Finland and Singapore. First and foremost, the study is a comparison between teacher education programmes in, on the one hand, Canada, Finland and Singapore, all of which…

  6. Influenza A(H10N7) Virus in Dead Harbor Seals, Denmark

    PubMed Central

    Hansen, Mette S.; Holm, Elisabeth; Hjulsager, Charlotte K.; Chriél, Mariann; Pedersen, Karl; Andresen, Lars O.; Abildstrøm, Morten; Jensen, Trine H.; Larsen, Lars E.

    2015-01-01

    Since April 2014, an outbreak of influenza in harbor seals has been ongoing in northern Europe. In Denmark during June–August, 152 harbor seals on the island of Anholt were found dead from severe pneumonia. We detected influenza A(H10N7) virus in 2 of 4 seals examined. PMID:25811098

  7. A Cultural and Comparative Perspective on Outdoor Education in New Zealand and "Friluftsliv" in Denmark

    ERIC Educational Resources Information Center

    Andkjaer, Soren

    2012-01-01

    The paper is based on a comparative and qualitative case study of "friluftsliv" in Denmark and outdoor education in New Zealand. Cultural analysis with a comparative cultural perspective informed the research approach. Configurational analysis was used as an important supplement to focus on cultural patterns linked to bodily movement. It…

  8. The Teaching of English Phonetics in Denmark: A Problem of Transference.

    ERIC Educational Resources Information Center

    Davidsen-Nielsen, Niels

    Since 1971 the approach adopted in the teaching of English phonetics in Denmark has been a contrastive one. In this paper it is argued that although the original contrastive hypothesis (Lado 1957) has to be modified and weakened, a contrastive approach is highly useful in learning and teaching the pronunciation of a foreign language. Selected…

  9. Education of Ethnic Minority Children in Denmark: Monocultural Hegemony and Counter Positions

    ERIC Educational Resources Information Center

    Horst, Christian; Gitz-Johansen, Thomas

    2010-01-01

    This paper explores the dominant approach to education of ethnic minorities in Denmark. Using the concept of hegemony and the political-science distinction between monocultural and multicultural positions as approaches towards a situation of increasing linguistic, ethnic and cultural diversity, the paper shows how a monocultural approach has…

  10. Prenatal Stress and Risk of Febrile Seizures in Children: A Nationwide Longitudinal Study in Denmark

    ERIC Educational Resources Information Center

    Li, Jiong; Olsen, Jorn; Obel, Carsten; Christensen, Jakob; Precht, Dorthe Hansen; Vestergaard, Mogens

    2009-01-01

    We aimed to examine whether exposure to prenatal stress following maternal bereavement is associated with an increased risk of febrile seizures. In a longitudinal population-based cohort study, we followed 1,431,175 children born in Denmark. A total of 34,777 children were born to women who lost a close relative during pregnancy or within 1 year…

  11. A Comparison of Autism Prevalence Trends in Denmark and Western Australia

    ERIC Educational Resources Information Center

    Parner, Erik T.; Thorsen, Poul; Dixon, Glenys; de Klerk, Nicholas; Leonard, Helen; Nassar, Natasha; Bourke, Jenny; Bower, Carol; Glasson, Emma J.

    2011-01-01

    Prevalence statistics for autism spectrum disorders (ASD) vary widely across geographical boundaries. Some variation can be explained by diagnostic methods, case ascertainment and age at diagnosis. This study compared prevalence statistics for two distinct geographical regions, Denmark and Western Australia, both of which have had population-based…

  12. Optimization as a Dispositive in the Production of Differences in Denmark Schools

    ERIC Educational Resources Information Center

    Hamre, Bjørn

    2014-01-01

    The theoretical framework of this paper is inspired by governmentality studies in education. The key concepts are problematization, formatting technologies, and dispositive. The paper begins with an empirical study conducted in Denmark of forty-four files from educational psychologists and articles from journals concerning schools and education.…

  13. Using English as a Medium of Instruction at University Level in Denmark: The Lecturer's Perspective

    ERIC Educational Resources Information Center

    Werther, Charlotte; Denver, Louise; Jensen, Christian; Mees, Inger M.

    2014-01-01

    More than 25% of the master's degrees in Denmark are taught using English as a medium of instruction (EMI), but not all university lecturers feel they have the appropriate academic English proficiency to meet the standard required. Based on interviews conducted at the Copenhagen Business School (CBS), this article sheds light on the challenges…

  14. Genome Sequence of Kocuria varians G6 Isolated from a Slaughterhouse in Denmark

    PubMed Central

    Raghupathi, Prem K.; Herschend, Jakob; Røder, Henriette L.; Sørensen, Søren J.

    2016-01-01

    We report here the first draft genome sequence of Kocuria varians G6, which was isolated from a meat chopper at a small slaughterhouse in Denmark. The 2.90-Mb genome sequence consists of 95 contigs and contains 2,518 predicted protein-coding genes. PMID:27034480

  15. Caught between Internationalisation and Immigration: The Case of Nepalese Students in Denmark

    ERIC Educational Resources Information Center

    Valentin, Karen

    2012-01-01

    An explicit marketisation and national profiling of Denmark as an attractive country for foreign students has resulted in an increasing number of students from poor countries in the global South, including Nepal, being admitted to Danish colleges and universities. The influx of students from these countries has led to several accusations against…

  16. European Gender Lessons: Girls and Boys at Scout Camps in Denmark, Portugal, Russia and Slovakia

    ERIC Educational Resources Information Center

    Nielsen, Harriet Bjerrum

    2004-01-01

    The article investigates the tensions between and within models of gender equality and gender complementarity by studying children who are in the midst of learning to apply these gender models in practice. Children (aged 11-15 years) were observed and interviewed while they participated in scout camps in Denmark, Portugal, Slovakia and Russia.…

  17. Manpower Policy in Denmark. OECD Reviews of Manpower and Social Policies, No. 14.

    ERIC Educational Resources Information Center

    Organisation for Economic Cooperation and Development, Paris (France).

    Two elements were identified as being of paramount importance in the examination of manpower policy in Denmark: (1) the division of responsibilities for matters of direct concern to the labor market between different branches of government and the social partners--an important facet of the social framework of a country, and (2) the impact of…

  18. Adult Education and the Challenges of Regional Development: Policy and Sustainability in North Denmark

    ERIC Educational Resources Information Center

    Rasmussen, Palle; Staugaard, Hans Jørgen

    2016-01-01

    Adult education is governed at many levels--internationally, nationally and locally. The authors of this paper look at the challenges, structures and practices of adult education policy at the local level, more specifically in North Denmark (Northern Jutland), one of the five administrative regions of the Danish nation-state. In many ways, the…

  19. Training Child Care Workers in Denmark. I. Training Group Day Care Workers.

    ERIC Educational Resources Information Center

    Wagner, Mary M.; Wagner, Marsden G.

    As part of the training of group day care workers in Denmark, training programs have been developed for each of the seven different types of day care centers. The theoretical education for each program is provided in four seminariums; practicum experiences occur in an actual day care facility. Each seminarium trains students in the care of only…

  20. Child Advocacy in Denmark: 70 Years of Experience with This "New" Idea.

    ERIC Educational Resources Information Center

    Wagner, Mary; Wagner, Marsden G.

    Denmark's child advocacy system is made up of local kommune (county) Child and Youth Welfare Committees which watch over the well-being of children. Each child and youth committee serves as an effective advocate for the children of its community in three areas: promotion, protection, and prevention. The committee's responsibility to promote…

  1. Training Child Care Workers in Denmark: II. Training Family Helpers and Family Day Care Mothers.

    ERIC Educational Resources Information Center

    Wagner, Mary; Wagner, Marsden G.

    This report describes the training of two kinds of paraprofessionals in child care in Denmark: the family helper who has considerable educational background, and the family day care mother for whom there are no educational prerequisites. The funding, the training, and the curriculum design of the paraprofessional programs are discussed. There is…

  2. Group Day Care in Denmark: A Century and a Half of Experience.

    ERIC Educational Resources Information Center

    Wagner, Mary G.; Wagner, Marsden G.

    The national and local organization and administration of group day care programs in Denmark are outlined in this report. Financing, basic programs, standards, and staff training in each of the four main child care groups are discussed under the following categories: cretches, kindergartens, afterschool groups, and youth clubs. Although all four…

  3. Assessing National Stereotypes in Language Attitude Studies: The Case of Class-Consciousness in Denmark.

    ERIC Educational Resources Information Center

    Ladegaard, Hans J.

    1998-01-01

    Describes a Danish language-attitude study, arguing that views presented in the literature often differ from people's private uncensored stereotypes. Surveys of people from four regions in Denmark investigated their attitudes after listening to voices with seven different regional dialects. Results indicated that people assigned social-class…

  4. Situation Report - Denmark, France, German Federal Republic, Luxembourg, Poland, Portugal, Romania, Spain, and Switzerland.

    ERIC Educational Resources Information Center

    International Planned Parenthood Federation, London (England).

    Data relating to population and family planning in nine foreign countries are presented in these situation reports. Countries included are Denmark, France, German Federal Republic, Luxembourg, Poland, Portugal, Romania, Spain, and Switzerland. Information is provided in the following areas where appropriate and if it is available: (1) statistics…

  5. Denmark's National Family Guidance Program: A Preventive Mental Health Program for Children and Families.

    ERIC Educational Resources Information Center

    Wagner, Marsden

    This document describes Denmark's 10-year (1965-75) program of cost-effective provision of social services to crisis families with children under the Danish 1964 Child and Youth Welfare Act. The program, voluntary and open to all families, provided preventive psychosocial services for children based on a family support system. The background to…

  6. The Children's Rights Convention in Denmark: A Status Report on Implementation

    ERIC Educational Resources Information Center

    Jorgensen, Per Schultz; Leth, Ingrid; Montgomery, Edith

    2011-01-01

    Research Findings: The United Nations Convention on the Rights of the Child was ratified by Denmark in 1991 but never incorporated into Danish legislation; instead the State party has chosen a stepwise implementation in legal and social praxis. However, this process mirrors a remarkable reluctance to approve the Convention as a legitimate part of…

  7. Vocational Education and Training in Denmark: Short Description. CEDEFOP Panorama Series.

    ERIC Educational Resources Information Center

    Cort, Pia

    Denmark has a uniform, nationwide vocational education and training (VET) system that provides qualifications that are valid throughout the country and recognized by employers and trade unions. Initial VET (IVET) includes the following components: VET, including commercial and technical training; basic social and health care training; agricultural…

  8. Explanations of sleep paralysis among Egyptian college students and the general population in Egypt and Denmark.

    PubMed

    Jalal, Baland; Simons-Rudolph, Joseph; Jalal, Bamo; Hinton, Devon E

    2014-04-01

    This cross-cultural study compared explanations of sleep paralysis (SP) in two countries and two groups with different levels of education in one country. Comparisons were made between individuals having experienced SP at least once in a lifetime from Cairo, Egypt (n = 89), Copenhagen, Denmark (n = 59), and the American University in Cairo, Egypt (n = 44). As hypothesized, participants from the general Egyptian population were more likely to endorse supernatural causal explanation of their SP compared to participants from Denmark; participants from the American University in Cairo were less likely to endorse supernatural causes of their SP compared to participants from the general Egyptian population. Moreover, participants from the American University in Cairo were marginally significantly more likely to endorse supernatural causes of their SP compared to participants from Denmark. Additionally, we explored which culturally bound explanations and beliefs about SP existed in Egypt and Denmark. We found that nearly half (48%) of the participants from the general Egyptian population believed their SP to be caused by the Jinn, a spirit-like creature with roots in Islamic tradition, which constitutes a culturally bound interpretation of the phenomenology of SP in this region of the world. Case studies are presented to illustrate these findings.

  9. The Role of the Social Partners in Youth and Adult Vocational Education and Training in Denmark.

    ERIC Educational Resources Information Center

    Sorensen, John Houman; Jensen, Grethe

    This document about Denmark has the following four aims: (1) to provide an overview on the vocational education and training system; (2) to describe and evaluate the social partners' (employers, employers' organizations, and unions) role in implementation, management, and control in relation to the vocational training system; (3) to outline the…

  10. The Danish Effect: Beginning to Explain High Well-Being in Denmark

    ERIC Educational Resources Information Center

    Biswas-Diener, Robert; Vitterso, Joar; Diener, Ed

    2010-01-01

    Although income and happiness have been linked at both the individual and national levels of analysis, few studies have specifically examined the different relationships between these two variables in affluent nations. This study investigates various measures of well-being in both the United States and Denmark. Respondents in both countries…

  11. The Concept of Permanent Education and Its Application in Denmark. Studies on Permanent Education, No. 2.

    ERIC Educational Resources Information Center

    Rasmussen, Werner

    A report is made to the Secretariat of the Council of Europe of a case study on the introduction of the concept of permanent education in Denmark. The supplies of education, which have been limited to clients in childhhod, adolescence, and yound adulthood, should now be distributed over a lifetime. Economic growth was formerly explained by input…

  12. Autopsy rate in suicide is low among elderly in Denmark compared with Finland.

    PubMed

    Ylijoki-Sørensen, Seija; Boldsen, Jesper Lier; Boel, Lene Warner Thorup; Bøggild, Henrik; Lalu, Kaisa; Sajantila, Antti

    2014-11-01

    National differences in the legislation on cause and manner of death investigation are reflected in a high autopsy rate in suicides in Finland and a low corresponding rate in Denmark. The consequences for mortality statistics of these different investigation practices on deaths classified as suicides in Denmark and Finland, respectively, are not known in detail. The aim of this article was to analyse autopsy rates in deaths classified as suicides, and to identify any differences in investigation practices in deaths with a comparable cause of death, but classified as unnatural deaths other than suicide. Data from the mortality registries were summarised for the years 2000, 2005 and 2010. Autopsy rates (total, forensic and medical) were analysed with regard to deaths classified as suicide, and they were compared for three age groups (1-50 years, 51-70 years and ≥71 years) and for causes of death. Deaths classified as suicide were compared with other unnatural classifications, and comparable causes of death were coded into six subgroups: poisonings, suffocations/strangulations, firearm discharges, drowning/submersions, explosions/flames and other/unspecified causes. The total autopsy rate for suicides was 99.8% in Finland and 13.2% in Denmark. Almost all of these autopsies were conducted as forensic autopsies. In the age group ≥71 years, Danish suicides outnumbered Finnish suicides (410 versus 283). The total autopsy rate was lower in the more senior age group in Denmark (19.5%, 9.9%, 5.6%), whereas it was consistently high in Finland (99.8%, 99.9%, 99.6%). Among Danish deaths due to poisonings, the autopsy rate was 89.5% when these were classified as accidents, but only 20.7% for cases classified as suicides. The number of deaths in the two Danish subgroups was comparable (550 versus 553). In Denmark, the decision regarding the need, if any, for a forensic autopsy is made during the external forensic examination of the body. Our study showed that the limited use

  13. Narcotics at street level in Denmark. A prospective investigation from 1995 to 2000.

    PubMed

    Simonsen, K W; Kaa, E; Nielsen, E; Rollmann, D

    2003-01-28

    This article describes an investigation of illicit drugs at street level in six selected police districts in different regions of Denmark. The investigation was carried out during a 6-year period from 1995 to 2000. During the period, a total of 1244 samples were examined, as about 200 samples were seized each year. A total of 94% of the seized samples were familiar drugs: heroin base, heroin hydrochloride, cocaine hydrochloride and amphetamine sulphate. Only 2% of the samples contained designer drugs. From having constituted 53% of the samples in 1995, the frequency of heroin base fell during the period to 27% of the samples in 2000. The frequency of heroin hydrochloride was unchanged. In the same period, the frequency of cocaine hydrochloride increased from 10% of the samples in 1995 to about 25% of the samples in 2000. Apart from a few exceptions, cocaine had the same extension in all regions of Denmark after 1996. Amphetamine was more frequent in the west of Denmark, while heroin hydrochloride was more frequent in central Denmark. The purity of heroin base was lower in the period 1997-1999 than in the other years. During the entire period, the purity of cocaine hydrochloride and amphetamine sulphate fell, while the purity of heroin hydrochloride was unchanged. No significant differences between the various regions of Denmark were detected during the period in the purity of heroin hydrochloride, heroin base, cocaine hydrochloride or amphetamine sulphate. MDMA was the most frequent designer drug, but other types of designer drugs such as MDA and MDE and the less common PMA, PMMA and MBDB were also found.

  14. Predictors of international students' psychological and sociocultural adjustment to the context of reception while studying at Aarhus University, Denmark.

    PubMed

    Ozer, Simon

    2015-12-01

    The number of international students engaging in intercultural education and thereby adjusting to cross-cultural transition has risen conspicuously as a consequence of globalization and increased mobility. This process of acculturation has been associated with increased creativity as well as adaptation challenges. This paper investigates international students' psychological and sociocultural adjustment to studying at Aarhus University in Denmark. Both international students (n = 129) and domestic students (n = 111) participated in the study. The international students did not report impaired psychological conditions as compared to the control group of domestic students. However, the international students reported a significantly lower level of social support. Social support and perceived discrimination were significant predictors of both psychological and sociocultural adjustment. Additionally, the level of English proficiency alone predicted sociocultural adjustment. Values of vertical individualism and horizontal collectivism predicted psychological adjustment. Finally, integration was found to be a significantly more adaptive acculturation orientation than separation in regard to sociocultural adjustment. These findings were discussed in relation to relevant international research and it was concluded that international students comprise a resourceful student sample and that the international academic environment at Aarhus University appears to be an adequately cultural and value-oriented good fit as a context of reception for the multicultural engagement of international students.

  15. Morbidity, Self-Perceived Health and Mortality Among non-Western Immigrants and Their Descendants in Denmark in a Life Phase Perspective.

    PubMed

    Jervelund, Signe Smith; Malik, Sanam; Ahlmark, Nanna; Villadsen, Sarah Fredsted; Nielsen, Annemette; Vitus, Kathrine

    2017-04-01

    To enable preventive policies to address health inequity across ethnic groups, this review overviews the current knowledge on morbidity, self-perceived health and mortality among non-Western immigrants and their descendants in Denmark. A systematic search in PUBMED, SCOPUS, Embase and Cochrane as well as in national databases was undertaken. The final number of publications included was 45. Adult immigrants had higher morbidity, but lower mortality compared to ethnic Danes. Immigrant children had higher mortality and morbidity compared to ethnic Danes. Immigrants' health is critical to reach the political goals of integration. Despite non-Western immigrants' higher morbidity than ethnic Danes, no national strategy targeting immigrants' health has been implemented. Future research should include elderly immigrants and children, preferably employing a life-course perspective to enhance understanding of parallel processes of societal adaptation and health.

  16. Spatial variability of drinking water iodine in Denmark: implications for future policy making

    NASA Astrophysics Data System (ADS)

    Voutchkova, Denitza; Ernstsen, Vibeke; Kristiansen, Søren; Hansen, Birgitte

    2014-05-01

    The iodine-an essential component of human thyroid hormones-is provided to our organisms naturally from the food and water and/or is added artificially to the diet. One of the major natural contributors to the dietary iodine intake in Denmark is the drinking water. Both insufficient or excessive iodine intake can cause health problems however the attention falls mainly on the iodine deficiency (ID). Denmark is classified to have mild ID, which is based on sub-national data only. On a bigger scale, in Europe, about 40% of the general population is estimated to suffer from insufficient iodine intake (based on recent update on the iodine status worldwide). A mandatory addition of iodine to the salt was introduced in 2001 in Denmark to address the population's mild deficiency. One of the components of the Danish monitoring program investigating the effect of the salt iodizing (DanThyr) was based on the geographical variation of drinking water iodine levels. More specifically, the location of the two DanThyr cohort studies was chosen to reflect the low concentrations in the western part of Denmark and higher concentration in the eastern part. However, the knowledge about the spatial variability of iodine in Danish ground- and drinking water at that time was quite limited and misrepresentation of the natural variability is suspected. The presented sampling campaign was completed in 2013, and includes 144 waterworks with annual abstraction of about 175 mio m3 groundwater (~45% of the total groundwater abstraction by all active public and private Danish waterworks). The results show a surprisingly complex spatial pattern concerning both the iodine concentrations and speciation. By estimating the dietary iodine intake from water and comparing it to the WHO recommendations, it becomes possible to recognize potentially deficient/excessive geographical areas. Moreover, it is demonstrated that drinking water iodine levels (major dietary iodine contributor in Denmark) can be

  17. Surveillance for avian influenza viruses in wild birds in Denmark and Greenland, 2007-10.

    PubMed

    Hulsager, Charlotte Kristiane; Breum, Solvej Østergaard; Trebbien, A Ramona; Handberg, A Kurt Jensen; Therkildsen, Ole Roland; Madsen, Jesper Johannes; Thoru, Kasper; Baroch, John A; Deliberto, Thomas J; Larsen, Lars Erik; Jorgensena, Poul Henrik

    2012-12-01

    In Denmark and Greenland, extensive surveillance of avian influenza (AI) viruses in wild bird populations has been conducted from 2007 through 2010. In Denmark, the surveillance consisted of passive surveillance of wild birds found dead or sick across Denmark and active surveillance of apparently healthy live birds in waterfowl reservoirs and along migratory flyways, birds living in proximity to domestic poultry, and hunted game birds. Dead birds were sampled by oropharyngeal swabbing. Healthy live wild birds were captured with nets, traps, or by hand and were sampled by swabbing of the oropharyngeal and cloacal tracts, or swabs were collected from fresh fecal droppings. Hunted game birds were delivered to game-handling establishments, where each bird was sampled by oropharyngeal and cloacal swabbing. During the 2007-10 period, a total of 11,055 wild birds were sampled in Denmark, of which 396 were birds that were found dead. In Greenland, samples were collected mainly from fecal droppings in breeding areas. Samples from 3555 live and apparently healthy wild birds were tested. All swab samples were tested by pan-influenza reverse transcriptase-PCR (RT-PCR), and the positive samples were further tested by H5/H7 specific RT-PCRs. H5/H7-positive samples were subjected to hemagglutination cleavage site sequencing for pathotyping. In addition, all RT-PCR-positive samples were subjected to virus isolation, and the virus isolates were subsequently subtyped. In Denmark, low pathogenic (LP) H5 viruses were detected throughout the period, in addition to a few LPAI H7 and several other subtypes. In Greenland, very few samples were positive for AI. None of them were found to be of the H5 or H7 subtypes by RT-PCR. Isolation of these viruses in eggs was unsuccessful; thus, they were not subtyped further. The findings did, however, demonstrate the presence of LPAI viruses in Greenland. For several water bird species overwintering in North America and northwest Europe

  18. The transition to non-lead rifle ammunition in Denmark: National obligations and policy considerations.

    PubMed

    Kanstrup, Niels; Thomas, Vernon G; Krone, Oliver; Gremse, Carl

    2016-09-01

    The issue of Denmark regulating use of lead-free rifle ammunition because of potential risks of lead exposure in wildlife and humans was examined from a scientific and objective policy perspective. The consequences of adopting or rejecting such regulation were identified. Denmark is obliged to examine this topic because of its national policy on lead reduction, its being a Party to the UN Bonn Convention on Migratory Species, and its role in protecting White-tailed Sea Eagles (Haliaeetus albicilla), a species prone to lead poisoning from lead ingestion. Lead-free bullets suited for deer hunting are available at comparable cost to lead bullets, and have been demonstrated to be as effective. National adoption of lead-free bullets would complete the Danish transition to lead-free ammunition use. It would reduce the risk of lead exposure to scavenging wildlife, and humans who might eat lead-contaminated wild game meat. Opposition from hunting organizations would be expected.

  19. Beyond motivation: on what it means to be a sperm donor in Denmark

    PubMed Central

    Mohr, Sebastian

    2014-01-01

    This paper, analyzing interviews with men that donate their semen in Denmark, explores what it means to be a sperm donor. Breaking with the assumption that men have a specific and clearly identifiable motivation to become sperm donors, this paper leaves the confinement of such an accountable actor model implied in asking for men's motivations to donate semen. Instead, the author describes the experiences of sperm donors to show how the moral, organizational, and biomedical-technological context of sperm donation in Denmark makes for enactments of moral selves as well as specific embodiments of masculinity. Instead of looking for motivations that can be accounted for, the author engages with the question of how donating semen affords men the experience of moral and gendered selves. PMID:25175292

  20. Does drinking water influence hospital-admitted sialolithiasis on an epidemiological level in Denmark?

    PubMed Central

    Schrøder, Stine; Homøe, Preben; Wagner, Niels; Vataire, Anne-Lise; Lundager Madsen, Hans Erik; Bardow, Allan

    2015-01-01

    Objectives Sialolithiasis, or salivary stones, is not a rare disease of the major salivary glands. However, the aetiology and incidence remain largely unknown. Since sialoliths are comprised mainly of calcium phosphate salts, we hypothesise that drinking water calcium levels and other elements in drinking water could play a role in sialolithiasis. Owing to substantial intermunicipality differences in drinking water composition, Denmark constitutes a unique environment for testing such relations. Design An epidemiological study based on patient data extracted from the National Patient Registry and drinking water data from the Geological Survey of Denmark and Greenland retrieved as weighted data on all major drinking water constituents for each of the 3364 waterworks in Denmark. All patient cases with International Statistical Classification of Diseases 10th Revision (ICD-10) codes for sialolithiasis registered between the years 2000 and 2010 were included in the study (n=3014) and related to the drinking water composition on a municipality level (n=98). Primary and secondary outcome measures Multiple regression analysis using iterative search and testing among all demographic and drinking water variables with sialolithiasis incidence as the outcome in search of possible relations among the variables tested. Results The nationwide incidence of hospital-admitted sialolithiasis was 5.5 cases per 100 000 citizens per year in Denmark. Strong relations were found between the incidence of sialolithiasis and the drinking water concentration of calcium, magnesium and hydrogen carbonate, however, in separate models (p<0.001). Analyses also confirmed correlations between drinking water calcium and magnesium and their concentration in saliva whereas this was not the case for hydrogen carbonate. Conclusions Differences in drinking water calcium and magnesium may play a role in the incidence of sialolithiasis. These findings are of interest because many countries have started

  1. Trace the Denmark Strait Overflow Water in an Eddy-Resolving Atlantic Simulation: Some Preliminary Results

    DTIC Science & Technology

    2013-05-01

    Trace the Denmark Strait overflow water in an eddy-resolving Atlantic simulation: some preliminary results Xiaobiao Xu ( COAPS /FSU), Alan...Wallcraft (NRL/SSC), Eric Chassignet ( COAPS /FSU) Thanks: Peter Rhines (UW) and William Schmitz May 21-23, Layered ocean modeling workshop, Ann Arbor, MI...Prediction Studies ( COAPS ),2000 Levy Avenue, Building A, Suite 292,Tallahassee,FL,32306-2741 8. PERFORMING ORGANIZATION REPORT NUMBER 9. SPONSORING

  2. Eureka’s Ministerial Conference (6th) Held in Copenhagen, Denmark on June 1988

    DTIC Science & Technology

    1989-03-13

    Materials i Robots, Manufacturing- andflirocess (26ntrol , Telecommunication-I- , Transportation • ( 4 d c - 19. ABSTRACT (Continue on reverse if...actual knowledge and new technology. The Industrial Application of Novel Plant Materials Netherlands, Denmark 17.20160 270/E Determination of the...growth-promoting agent. Medical Materials (Biomaterials) Germany, Greece 0.45/60 294/E The development of biological composite materials whose phases are

  3. Area Report. Developments in Microwave Antennas and Applications in Sweden, Denmark, and Norway.

    DTIC Science & Technology

    1980-12-31

    if by block nimber) Denmark anechoic chamber near field testing Norway microwaves phased arrays Sweden industrial application radiometer antennas of...Stockholm. At the University of Gothenburg, phased - array technology is being developed for relative- ly small and simple systems and specific...whether to investigate some microwave antenna systems, for example, phased arrays . The main efforts in Norway are found at the Technical University of

  4. Genetic analysis of avian influenza virus from wild birds and mallards reared for shooting in Denmark.

    PubMed

    Handberg, Kurt Jensen; Therkildsen, Ole Roland; Jørgensen, Poul Henrik

    2010-03-01

    Denmark forms a geographical bottleneck along the migration route of many water birds breeding from northeastern Canada to north Siberia that gather to winter in Europe and Africa. Potentially, the concentration of such large numbers of water birds enhances the risk of avian influenza virus (AIV) introduction to domestic poultry. In 2003, Denmark initiated a nationwide survey of AIV in wild birds and mallards reared for shooting. Partial sequence analysis of the six internal genes from a total of 12 low pathogenic (LP) AIV isolates obtained in 2003 showed that genes from these viruses were closely related with genes from AIV circulating in northern Europe. For the Danish sequences only the PB2 and NS genes differ, so they cluster to more than one cluster in the phylogenetic trees. In spring 2006, highly pathogenic (HP) AIV H5N1 was detected in 44 cases of wild birds in Denmark. Sequence analysis of the HP H5N1 virus genome showed that it was not related to the LPAIV isolated previously, but closely related to the HPAIV H5 (Asian type) detected in the rest of Europe at that time. Even though only partial sequences were applied, this gave the idea for future full-length sequence studies.

  5. Twenty-year survey of the epidemiology of hepatitis B in Denmark: effect of immigration.

    PubMed

    Gjørup, I E; Smith, E; Borgwardt, L; Skinhøj, P

    2003-01-01

    Implementation of hepatitis B virus (HBV) vaccination is being considered in Denmark. Therefore, a 20 y survey on the epidemiology of HBV infection was performed. All notified cases of acute HBV infection in Denmark from 1982 to 2002 were reviewed retrospectively and all available data from 1970 to 2001 on the prevalence of hepatitis B surface antigen (HBsAg) in different groups of the Danish population were studied. The notified annual incidence of acute HBV infection has declined from more than 200 cases to fewer than 50 cases in 2001. In the indigenous population there has been a similar decline in prevalence of HBsAg carriers, from 0.15 to 0.03%, but owing to immigration of new HBsAg carriers from developing countries the overall number of carriers has not changed. The small effect of immigration on the incidence of acute HBV infections as well as the decreasing prevalence of HBsAg carriers among Danes should be taken into account when planning new vaccination strategies in Denmark.

  6. Bovine virus diarrhea virus in free-living deer from Denmark.

    PubMed

    Nielsen, S S; Roensholt, L; Bitsch, V

    2000-07-01

    Free-living deer are suggested as a possible source of infection of cattle with bovine virus diarrhea (BVD) virus. To examine this hypothesis blood samples from 476 free-living deer were collected during two different periods and tested for BVD virus and antibody in Denmark. In 1995-96, 207 animals were tested. These included 149 roe deer (Capreolus capreolus), 29 fallow deer (Dama dama), 20 red deer (Cervus elaphus) and one sika deer (Cervus sika). For the remaining eight animals no species information was available. In 1998-99, 269 animals were tested including 212 roe deer and 57 red deer. The animals were selected from areas with a relatively high prevalence of cattle herds with a BVD persistent infection status in 1997 and 1998. All 207 samples from 1995-96 were found antibody-negative except two samples from red deer. Only 158 of the 207 samples were tested for virus and were all found negative. Of the 269 samples from 1998-99 all but one were antibody negative. The positive sample was from a red deer. All samples were virus-negative. It appears that BVD infection does not occur in roe deer in Denmark. The presence of antibody in a few red deer from various districts in Jutland probably results from cattle to deer transmission, rather than spread among deer. Hence, the possibility of free-living deer as a source of infection for cattle in Denmark seems to be remote.

  7. A roadmap for comparing readmission policies with application to Denmark, England, Germany and the United States.

    PubMed

    Kristensen, Søren Rud; Bech, Mickael; Quentin, Wilm

    2015-03-01

    Hospital readmissions receive increasing interest from policy makers because reducing unnecessary readmissions has the potential to simultaneously improve quality and save costs. This paper reviews readmission policies in Denmark, England, Germany and the United States (Medicare system). The suggested roadmap enables researchers and policy makers to systematically compare and analyse readmission policies. We find considerable differences across countries. In Germany, the readmission policy aims to avoid unintended consequences of the introduction of DRG-based payment; it focuses on readmissions of individual patients and hospitals receive only one DRG-based payment for both the initial and the re-admission. In Denmark, England and the US readmission policies aim at quality improvement and focus on readmission rates. In Denmark, readmission rates are publicly reported but payments are not adjusted in relation to readmissions. In England and the US, financial incentives penalise hospitals with readmission rates above a certain benchmark. In England, this benchmark is defined through local clinical review, while it is based on the risk-adjusted national average in the US. At present, not enough evidence exists to give recommendations on the optimal design of readmission policies. The roadmap can be a tool for systematically assessing how elements of other countries' readmission policies can potentially be adopted to improve national policies.

  8. Measuring integrated care.

    PubMed

    Strandberg-Larsen, Martin

    2011-02-01

    additionally used to investigate the use of joint health planning as a tool for coordination of regional-local healthcare delivery. Analysis of secondary data from the Danish healthcare system and Kaiser Permanente, California were used to compare population characteristics, professional staff, delivery structure, utilisation, quality measures and direct costs. A cross-sectional survey among primary care clinicians in Denmark and in Kaiser Permanente, Northern California was completed to allow for comparison of clinical integration in the two systems and system specific associated factors. In this thesis a conceptual framework and a model for assessment of the conditions for integrations as an intermediate healthcare system outcome are presented. Furthermore, the results show that integrated healthcare delivery can be measured: 24 methods are available and some are highly developed. However, the field is still in its early phase and guidelines for how to proceed are devised. It was confirmed on a national level that integration of care is a widespread challenge, and that only half or less than half of patients in need of integrated services receive such care. Options for decision makers and managers are discussed. From a theoretical perspective joint health plans as applied in Denmark do not match the degree of complexity in the healthcare system. It was therefore in agreement with the theoretical findings when major stakeholders agreed that the joint health plans had not been effective as a tool for coordination. Joint health planning processes should actively engage all stakeholders and a high degree of recurrent feedback are warranted. When comparing Kaiser Permanente, California with the Danish healthcare system, our study suggest that Kaiser Permanente has a population with more documented disease and higher operating costs, and performs better than the Danish healthcare system on the observed quality measures. Substantial differences were found in the perception of

  9. Metformin initiation and renal impairment: a cohort study in Denmark and the UK

    PubMed Central

    Christiansen, Christian Fynbo; Ehrenstein, Vera; Heide-Jørgensen, Uffe; Skovbo, Stine; Nørrelund, Helene; Sørensen, Henrik Toft; Li, Lin; Jick, Susan

    2015-01-01

    Objectives To estimate prevalence of renal impairment, rate of decline in kidney function and changes in metformin use after decline in kidney function, in metformin initiators. Design, setting and participants We conducted this 2-country cohort study using routine data from northern Denmark and the UK during 2000–2011. We included metformin initiators among patients aged ≥30 years with medically treated diabetes. Main outcome measures We described patients’ demographics, comorbidity, co-medications and their estimated glomerular filtration rates (eGFR). Furthermore, we described the patients’ characteristics according to eGFR level. Finally, we examined the rate of any decline in eGFR and changes in metformin use within 90 days after first decline in eGFR during follow-up. Results We included 124 720 metformin initiators in the 2 countries. Prevalence of eGFR <60 mL/min/1.73 m2 among metformin initiators was 9.0% in Denmark and 25.2% in the UK. In contrast, prevalence of eGFR values <30 mL/min/1.73 m2 among metformin initiators was 0.3% in Denmark and 0.4% in the UK. Patients with renal impairment were older and more likely to have received cardiovascular drugs. Incidence rate of decline in renal function was 4.92 per 100 person-years (95% CI 4.76 to 5.09) in Denmark and 7.48 per 100 person-years (95% CI 7.39 to 7.57) in the UK. The proportion of patients continuing metformin use, even after a first decline brought the eGFR below 30 mL/min/1.73 m2, was 44% in Denmark and 62% in the UK. There was no clinically significant dose reduction with decreasing baseline eGFR level discernible from the data. Conclusions Mild to moderate renal impairment was common among metformin initiators, while severe renal impairment was uncommon. Patients with severe renal impairment frequently continued receiving/redeeming metformin prescriptions even 90 days after eGFR decline. PMID:26338686

  10. Trends in occurrence of antimicrobial resistance in Campylobacter jejuni isolates from broiler chickens, broiler chicken meat, and human domestically acquired cases and travel associated cases in Denmark.

    PubMed

    Skjøt-Rasmussen, Line; Ethelberg, Steen; Emborg, Hanne-Dorthe; Agersø, Yvonne; Larsen, Lars S; Nordentoft, Steen; Olsen, Stefan S; Ejlertsen, Tove; Holt, Hanne; Nielsen, Eva Møller; Hammerum, Anette M

    2009-05-31

    Campylobacter jejuni is a frequent cause of bacterial gastroenteritis. Often it causes self-limiting disease but severe or prolonged cases may require antimicrobial treatment. The agricultural use of antimicrobial agents selects for resistance among C. jejuni which is transmitted to humans via food. In Denmark, the use of fluoroquinolones in animal husbandry has been restricted since 2003. The purpose of the present study was to look at trends in occurrence of resistance among C. jejuni from broiler chickens, broiler chicken meat and human domestically acquired or travel associated cases. From 1997 through 2007, C. jejuni isolates were obtained from The Danish Integrated Antimicrobial Resistance Monitoring and Research Programme (DANMAP) and susceptibility tested for ciprofloxacin, erythromycin, nalidixic acid, and tetracycline. Erythromycin resistance was at a low level in all the reservoirs during the study period. Resistance to ciprofloxacin, nalidixic acid and tetracycline was significantly higher in C. jejuni from imported broiler chicken meat compared to Danish broiler chicken meat. In domestically acquired human C. jejuni isolates, resistance to ciprofloxacin and nalidixic acid was for most years significantly higher compared to the level found in isolates from Danish broiler chicken meat, whereas the resistance level was similar to the level found in isolates from imported broiler chicken meat. Imported broiler chicken meat may therefore contribute to the high level of ciprofloxacin and nalidixic acid resistance in C. jejuni isolates from domestically acquired human infections. In 2006 and 2007, the occurrence of resistance to ciprofloxacin, nalidixic acid and tetracycline was significantly higher in travel associated C. jejuni isolates compared to isolates acquired domestically. Even though the use of fluoroquinolones is restricted for animal use in Denmark, Danes are still often infected by fluoroquinolone resistant C. jejuni from imported chicken meat or

  11. Gauge Integration

    DTIC Science & Technology

    2002-09-01

    convergence theorems. Lebesgue developed his theory of measure and integration to address these shortcomings. His integral is more powerful in the...This relatively recent integral possesses the intuitive description of the Riemann integral, with the power of the Lebesgue integral. The purpose of this...strong convergence theorems. Lebesgue developed his theory of measure and integration to address these shortcomings. His integral is more powerful in the

  12. Integrated Means Integrity

    ERIC Educational Resources Information Center

    Odegard, John D.

    1978-01-01

    Describes the operation of the Cessna Pilot Center (CPC) flight training systems. The program is based on a series of integrated activities involving stimulus, response, reinforcement and association components. Results show that the program can significantly reduce in-flight training time. (CP)

  13. Comparing sensitivity and specificity of screening mammography in the United States and Denmark.

    PubMed

    Kemp Jacobsen, Katja; O'Meara, Ellen S; Key, Dustin; S M Buist, Diana; Kerlikowske, Karla; Vejborg, Ilse; Sprague, Brian L; Lynge, Elsebeth; von Euler-Chelpin, My

    2015-11-01

    Delivery of screening mammography differs substantially between the United States (US) and Denmark. We evaluated whether there are differences in screening sensitivity and specificity. We included screens from women screened at age 50-69 years during 1996-2008/2009 in the US Breast Cancer Surveillance Consortium (BCSC) (n = 2,872,791), and from two population-based mammography screening programs in Denmark (Copenhagen, n = 148,156 and Funen, n = 275,553). Women were followed-up for 1 year. For initial screens, recall rate was significantly higher in BCSC (17.6%) than in Copenhagen (4.3%) and Funen (3.1%). Sensitivity was fairly similar in BCSC (91.8%) and Copenhagen (90.5%) and Funen (92.5%). At subsequent screens, recall rates were 8.8%, 1.8% and 1.4% in BCSC, Copenhagen and Funen, respectively. The BCSC sensitivity (82.3%) was lower compared with that in Copenhagen (88.9%) and Funen (86.9%), but when stratified by time since last screen, the sensitivity was similar. For both initial and subsequent screenings, the specificity of screening in BCSC (83.2% and 91.6%) was significantly lower than that in Copenhagen (96.6% and 98.8%) and Funen (97.9% and 99.2%). By taking time since last screen into account, it was found that American and Danish women had the same probability of having their asymptomatic cancers detected at screening. However, the majority of women free of asymptomatic cancers experienced more harms in terms of false-positive findings in the US than in Denmark.

  14. Ground truth and detection threshold from WWII naval clean-up in Denmark

    NASA Astrophysics Data System (ADS)

    Larsen, Tine B.; Dahl-Jensen, Trine; Voss, Peter

    2013-04-01

    The sea bed below the Danish territorial waters is still littered with unexploded mines and other ammunition from World War II. The mines were air dropped by the RAF and the positions of the mines are unknown. As the mines still pose a potential threat to fishery and other marine activities, the Admiral Danish Fleet under the Danish Navy searches for the mines and destroy them by detonation, where they are found. The largest mines destroyed in this manner in 2012 are equivalent to 800 kg TNT each. The Seismological Service at the National Geological Survey of Denmark and Greenland is notified by the navy when ammunition in excess of 100 kg TNT is detonated. The notifications include information about position, detonation time and the estimated amount of explosives. The larger explosions are clearly registered not only on the Danish seismographs, but also on seismographs in the neighbouring countries. This includes the large seismograph arrays in Norway, Sweden, and Finland. Until recently the information from the Danish navy was only utilized to rid the Danish earthquake catalogue of explosions. But the high quality information provided by the navy enables us to use these ground truth events to assess the quality of our earthquake catalogue. The mines are scattered though out the Danish territorial waters, thus we can use the explosions to test the accuracy of the determined epicentres in all parts of the country. E.g. a detonation of 135 kg in Begstrup Vig in the central part of Denmark was located using Danish, Norwegian and Swedish stations with an accuracy of less than 2 km from ground truth. A systematic study of the explosions will sharpen our understanding of the seismicity in Denmark, and result in a more detailed understanding of the detection threshold. Furthermore the study will shed light on the sensitivity of the network to various seismograph outages.

  15. Rapid spread of Schmallenberg virus-infected biting midges (Culicoides spp.) across Denmark in 2012.

    PubMed

    Rasmussen, L D; Kirkeby, C; Bødker, R; Kristensen, B; Rasmussen, T B; Belsham, G J; Bøtner, A

    2014-02-01

    Detection of Schmallenberg virus RNA, using real-time RT-PCR, in biting midges (Culicoides spp.) caught at 48 locations in 2011 and four well-separated farms during 2012 in Denmark, revealed a remarkably rapid spread of virus-infected midges across the country. During 2012, some 213 pools of obsoletus group midges (10 specimens per pool) were examined, and of these, 35 of the 174 parous pools were Schmallenberg virus RNA positive and 11 of them were positive in the heads. Culicoides species-specific PCRs identified both C. obsoletus and C. dewulfi as vectors of Schmallenberg virus.

  16. Suicide by carbon monoxide from car exhaust-gas in Denmark 1995-1999.

    PubMed

    Thomsen, Asser H; Gregersen, Markil

    2006-08-10

    In the period 1995-1999 there were 388 car exhaust-gas suicides in Denmark. Of these 343 (88.4%) were men and 45 (11.6%) were women, the average age being 47 years. The car exhaust-gas suicides made up 9.3% of all suicides in Denmark in the period. The corresponding rate was 11.7% for men and 3.7% for women. In rural areas a larger part of all suicides were committed with car exhaust-gas compared to the more densely populated areas. Mental disease was diagnosed in 124 (32.0%) cases. A suicide note was found in 165 (42.5%) cases. A hose was fitted to the exhaust pipe in 334 (86.1%) cases. Of these the 234 (60.3%) occurred outside, typically in a forest area, while 76 (19.6%) occurred in a closed garage. All the 54 (13.9%) cases with no hose fitted to the exhaust pipe occurred in a garage. Seven (1.8%) victims were found in a burning or burnt-out car, where the following investigation revealed that it was actually a car exhaust-gas suicide. Carboxyhemoglobin was measured in 26 (6.7%) victims. In two of these victims no carboxyhemoglobin was found, as they had survived for some time after the poisoning. The average saturation of the remaining victims was 67%, the lowest saturation being 20% and the highest being 84%. In the period 1969-1987 the number of car exhaust-gas suicides in Denmark increased from 50 to approximately 190 per year and the rate of car exhaust-gas suicides compared to all suicides increased from approximately 5% to approximately 13%. In 1987-1999 these figures decreased from approximately 190 to 63 per year and from 13% to approximately 8%. During these 30 years the number of passenger cars in Denmark doubled, which explains the increase in car exhaust-gas suicides during 1969-1987. A possible explanation for the decrease in 1987-1999 is the introduction of the catalytic converter, which was made mandatory in 1990. We anticipate that car exhaust-gas suicides will continue to decrease in numbers, as more cars are equipped with catalytic converters.

  17. Outbreaks of shigellosis in Denmark and Australia associated with imported baby corn, August 2007--final summary.

    PubMed

    Lewis, H C; Kirk, M; Ethelberg, S; Stafford, R; Olsen, Kep; Nielsen, E M; Lisby, M; Madsen, S B; Mølbak, K

    2007-10-04

    The recently reported concurrent outbreaks of Shigella sonnei infections in Denmark and Australia have been found to be linked to a common baby corn packing house in Thailand via trace-back of the distribution chain. Distribution records indicated that three additional countries received affected product from the implicated Thai packing house during the period of potential contamination. These countries were notified through the World Health Organization's International Food Safety Authorities Network (INFOSAN). Associated cases of S. sonnei have not been reported in these three countries.

  18. Regional analysis of groundwater nitrate concentrations and trends in Denmark in regard to agricultural influence

    NASA Astrophysics Data System (ADS)

    Hansen, B.; Dalgaard, T.; Thorling, L.; Sørensen, B.; Erlandsen, M.

    2012-08-01

    The act of balancing between an intensive agriculture with a high potential for nitrate pollution and a drinking water supply almost entirely based on groundwater is a challenge faced by Denmark and similar regions around the globe. Since the 1980s, regulations implemented by Danish farmers have succeeded in optimizing the N (nitrogen) management at farm level. As a result, the upward agricultural N surplus trend has been reversed, and the N surplus has reduced by 30-55% from 1980 to 2007 depending on region. The reduction in the N surplus served to reduce the losses of N from agriculture, with documented positive effects on nature and the environment in Denmark. In groundwater, the upward trend in nitrate concentrations was reversed around 1980, and a larger number of downward nitrate trends were seen in the youngest groundwater compared with the oldest groundwater. However, on average, approximately 48% of the oxic monitored groundwater has nitrate concentrations above the groundwater and drinking water standards of 50 mg l-1. Furthermore, trend analyses show that 33% of all the monitored groundwater has upward nitrate trends, while only 18% of the youngest groundwater has upward nitrate trends according to data sampled from 1988-2009. A regional analysis shows a correlation between a high level of N surplus in agriculture, high concentrations of nitrate in groundwater and the largest number of downward nitrate trends in groundwater in the livestock-dense northern and western parts of Denmark compared with the southeastern regions with lower livestock densities. These results indicate that the livestock farms dominating in northern and western parts of Denmark have achieved the largest reductions in N surpluses. Groundwater recharge age determinations allow comparison of long-term changes in N surplus in agriculture with changes in oxic groundwater quality. The presented data analysis is based on groundwater recharged from 1952-2003, but sampled from 1988

  19. Regional analysis of groundwater nitrate concentrations and trends in Denmark in regard to agricultural influence

    NASA Astrophysics Data System (ADS)

    Hansen, B.; Dalgaard, T.; Thorling, L.; Sørensen, B.; Erlandsen, M.

    2012-05-01

    The act of balancing between an intensive agriculture with a high potential for nitrate pollution and a~drinking water supply almost entirely based on groundwater is a challenge faced by Denmark and similar regions around the globe. Since the 1980s, regulations implemented by Danish farmers have succeeded in optimizing the N (nitrogen) management at farm level. As a result, the upward agricultural N surplus trend has been reversed, and the N surplus has reduced by 30-55 % from 1980 to 2007 depending on region. The reduction in the N surplus served to reduce the losses of N from agriculture, with documented positive effects on nature and the environment in Denmark. In groundwater, the upward trend in nitrate concentration was reversed around 1980, and a larger number of downward nitrate trends were seen in the youngest groundwater compared with the oldest groundwater. However, on average, approximately 48 % of the oxic monitored groundwater has nitrate concentrations above the groundwater and drinking water standards of 50 mg l-1. Furthermore, trend analyses show that 33 % of all the monitored groundwater has upward nitrate trends, while only 18 % of the youngest groundwater has upward nitrate trends according to data sampled from 1988-2009. A regional analysis shows a correlation between a high level of N surplus in agriculture, high concentrations of nitrate in groundwater and the largest number of downward nitrate trends in groundwater in the livestock-dense northern and western parts of Denmark compared with the south-eastern regions with lower livestock densities. These results indicate that the livestock farms dominating in northern and western parts of Denmark have achieved the largest reductions in N surpluses. Groundwater recharge age determinations allow comparison of long-term changes in N surplus in agriculture with changes in oxic groundwater quality. The presented data analysis is based on groundwater recharged from 1952-2003, but sampled from 1988

  20. Climatic changes of extreme precipitation in Denmark from 1874 to 2100

    NASA Astrophysics Data System (ADS)

    Arnbjerg-Nielsen, Karsten; Bülow Gregersen, Ida; Sunyer, Maria; Madsen, Henrik; Rosbjerg, Dan

    2014-05-01

    During the past 30 years rather dramatic changes in extreme precipitation have been observed in Denmark. These changes are mainly in the frequency of extreme events, but there is also a tendency towards more severe events. Both are considered effects of anthropogenic climate change. The increase in precipitation extremes has led to inundations in most of the larger cities during the last 10 years. The flood in Copenhagen in 2011 implied the second highest damage costs measured in Denmark during the last 100 years. To establish cities that are resilient to pluvial floods robust projections of the frequency and intensity of extreme precipitation events in a changing climate are needed. Additionally, it is equally important to understand the natural variation on which the anthropogenic changes are imposed. This study presents the results of a coordinated effort to estimate the changes and uncertainties in Danish design rainfall. Trends and oscillations are identified in five daily precipitation records from 1874 to present, 83 records from high-resolution rain-gauges from 1979 to present and 18 state-of-the-art climate model simulations. It is shown that the frequency of extreme events in the past has oscillated with a cycle of 25-35 years, a behavior that can in part be explained by sea level pressure differences over the Atlantic. Projections based on the historical observations suggest that precipitation extremes in the Eastern part of Denmark should have been ascending in the last two decades. However, the increase has continued longer than expected and with larger amplitude in the most recent years. This indicates a likely influence from anthropogenic greenhouse gas emissions. With the complex combination of general increase and natural variation several additional years of observation are needed before this hypothesis can be evaluated by statistical means. Extensive analysis of 18 different regional climate model (RCM) simulations shows that anthropogenic

  1. The Tragedy of Hamlet, Son of an Organic Chemist of Denmark

    NASA Astrophysics Data System (ADS)

    Brisbois, Ronald G.

    2004-04-01

    Once faced with structure reactivity relationships in the context of nucleophilic substitution at sp 3 carbon, introductory organic chemistry students must compare and contrast the various attributes and ramifications of S N 2 versus S N 1 reaction pathways. The dramatic (even melodramatic) way in which some students ask such comparative questions inspired a parody of Hamlet's famous to be or not to be soliloquy. Herein, Hamlet (the son of an organic chemist of Denmark) is the surrogate of any and every student as he uses a thoroughly Shakespearian approach to sorting out some of the key distinguishing features of S N 2 versus S N 1 reactions.

  2. On the origin and propagation of Denmark Strait Overflow Water Anomalies in the Irminger Basin

    NASA Astrophysics Data System (ADS)

    Jochumsen, Kerstin; Quadfasel, Detlef; Köllner, Manuela; Dye, Stephen; Rudels, Bert; Valdimarsson, Hedinn

    2015-04-01

    Denmark Strait Overflow Water (DSOW) supplies the densest contribution to North Atlantic Deep Water and is monitored at several locations in the subpolar North Atlantic. We present an analysis of observed hydrographic (temperature and salinity) and velocity time series from three multiple-mooring arrays to quantify the variability and to track anomalies of DSOW: (1) at the Denmark Strait sill, (2) at 180 km downstream (south of Dohrn Bank) and (3) at a further 320 km downstream on the east Greenland continental slope near Tasiilaq (formerly Angmagssalik). The aim of the combined arrays is to cover the overflow plume and its modifications due to its descent and mixing with ambient waters from the sill of Denmark Strait to approx. 2000 m depth in the northern Irminger Basin. Eddy variability dominates the high frequency variations in all DSOW records. Variability on time scales from interannual to weekly is present at all moorings, but no long term trends are detected in the time series. The seasonal cycle is of no importance for the properties measured at the sill, but its significance increases with downstream distance. A low pass filter (cut-off at 20 days) is applied to the time series in order to remove synoptic scale variations: single eddies are likely not traceable and probably merge with each other or fade along the descending pathway of the DSOW plume. The hydrographic time series from different moorings within each mooring array show coherent signals, while the velocity fluctuations are only weakly correlated. Lagged correlations of anomalies between the arrays reveal propagation from the sill of Denmark Strait to the Angmagssalik array in potential temperature with an average propagation time of 16 days. Despite a difference of 1.5°C between the mean temperatures at both arrays, which are about 500 km away from each other, temperature anomalies can be traced along the DSOW pathway. In contrast, the correlations in salinity are low and only significant

  3. Formation of Denmark strait overflow water by mixing in the East Greenland Current

    SciTech Connect

    Strass, V.H.; Fahrbach, E.; Schauer, U.; Sellmann, L. )

    1993-04-15

    The Greenland, Iceland, and Norwegian seas are major sources of water feeding the North Atlantic Deep Water in the worlds present ocean circulation. The authors report on data collected in 1987 through 1989 which indicate that a mass of water with characteristics of the Denmark Strait Overflow Water (DSOW) is formed in the East Greenland Current. The DSOW has been observed to have a residence time of 3 to 4 years at the surface before spilling southward. This provides a very fast transfer of surface water with atmospheric signatures into the deep ocean. They offer explanations for the formation of this water mass.

  4. Burn injury during long-term oxygen therapy in Denmark and Sweden: the potential role of smoking

    PubMed Central

    Tanash, Hanan A; Ringbaek, Thomas; Huss, Fredrik; Ekström, Magnus

    2017-01-01

    Background Long-term oxygen therapy (LTOT) increases life expectancy in patients with COPD and severe hypoxemia. Smoking is the main cause of burn injury during LTOT. Policy regarding smoking while on LTOT varies between countries. In this study, we compare the incidence of burn injury that required contact with a health care specialist, between Sweden (a country with a strict policy regarding smoking while on LTOT) and Denmark (a country with less strict smoking policy). Methods This was a population-based, cohort study of patients initiating LTOT due to any cause in Sweden and Denmark. Data on diagnoses, external causes, and procedures were obtained from the Swedish and Danish National Patient Registers for inpatient and outpatient care. Patients were followed from January 1, 2000, until the first of the following: LTOT withdrawal, death, or study end (December 31, 2009). The primary end point was burn injury during LTOT. Results A total of 23,741 patients received LTOT in Denmark and 7,754 patients in Sweden. Most patients started LTOT due to COPD, both in Sweden (74%) and in Denmark (62%). The rate of burn injury while on LTOT was higher in Denmark than in Sweden; 170 (95% confidence interval [CI], 126–225) vs 85 (95% CI, 44–148) per 100,000 person-years; rate ratio 2.0 (95% CI, 1.0–4.1). The risk remained higher after adjustment for gender, age, and diagnosis in multivariate Cox regression, hazard ratio 1.8 (95% CI, 1.0−3.5). Thirty-day mortality after burn injury was 8% in both countries. Conclusion Compared to Sweden, the rate of burn injury was twice as high in Denmark where smoking is not a contraindication for prescribing LTOT. PMID:28123292

  5. Fusobacterium necrophorum findings in Denmark from 2010 to 2014 using data from the Danish microbiology database.

    PubMed

    Bank, Steffen; Jensen, Anders; Nielsen, Hanne Merete; Kristensen, Lena Hagelskjaer; Voldstedlund, Marianne; Prag, Jørgen

    2016-12-01

    Fusobacterium necrophorum findings in Denmark and estimation of the incidence of F. necrophorum bacteraemia was described using data from the nationwide Danish microbiology database (MiBa). All microbiological reports on any Fusobacterium species in Denmark were extracted for a period of 5 years from 2010 to 2014 from MiBa and from the local department of clinical microbiology. The overall incidence of F. necrophorum bacteraemia from 2010 to 2014 was 2.8 cases per million/year vs 9.4 in the age group 15-24 years. F. necrophorum was rare in blood cultures from children and middle-aged patients and then raised again. However, 48 of 232 cases of Fusobacterium bacteraemia were not identified to species level, so the incidences of F. necrophorum bacteraemia may be underestimated in our study. F. necrophorum was found in throat swabs in the age group between 13 and 40 years and in otitis media in children below 2 years in those departments which performed anaerobic culture. The incidence of F. necrophorum bacteraemia found was comparable to earlier reported figures for Lemierre's syndrome. Fusobacterium bacteraemia should always be identified to species level.

  6. [Extrapulmonary tuberculosis in Denmark. A review of the incidence, localization and therapy].

    PubMed

    Kok-Jensen, A; Viskum, K

    1994-09-12

    In Denmark, just under 20% of tuberculosis (TB) cases amongst Danes and 25-30% of cases amongst people of foreign nationalities are made up of isolated extrapulmonary (EP) TB. The incidence among Danes is falling, whereas an increasing amount of EP TB cases are found among foreigners due to continued immigration, and these now constitute 50% of all cases of EP TB. EP TB is found among older Danes and younger foreigners. The HIV/AIDS epidemic has not had any effect on the incidence of TB and EP TB in Denmark. EP TB is most frequently found in lymph nodes and the urogenital system. Since the disease is rare, it may be overlooked; it should be considered as a differential diagnosis in unresolved cases, particularly in immigrants from countries with a high prevalence of TB. Treatment is as for pulmonary TB, namely "four drug" therapy for six months. Surgical intervention is rarely required. Supplementation with oral steroids may be useful in very special cases.

  7. A comparative analysis of coverage decisions for outpatient pharmaceuticals: evidence from Denmark, Norway and Sweden.

    PubMed

    Grepstad, Mari; Kanavos, Panos

    2015-02-01

    This study analyses the reasons for differences and similarities in coverage recommendations for outpatient pharmaceuticals in Denmark, Norway and Sweden, following HTA appraisals. A comparative analysis of all outpatient drug appraisals carried out between January 2009 and December 2012, including an analysis of divergent coverage recommendations made by all three countries was performed. Agreement levels between HTA agencies were measured using kappa scores. Consultations with stakeholders in the three countries were carried out to complement the discussion on HTA processes and reimbursement outcomes. Nineteen outpatient drug-indication pairs appraised in each of the three countries were identified, of which 6 pairs (32%) had divergent coverage recommendations. An uneven distribution of coverage recommendations was observed, with the highest overlap in appraisals between Norway and Sweden (free-marginal kappa 0.89). Similarities were found in priority setting principles, mode of appraisal and reasoning for coverage recommendations. The study shows that health economic evaluation is less prominent or explicit in outpatient drug appraisals in Denmark than in Norway and Sweden, that all three countries could benefit from improved communication between appraisers and manufacturers, and that final coverage recommendations rely on factors other than safety, comparative efficacy or cost-effectiveness.

  8. [The first set of legislation for doctors in Denmark and its source of inspiration].

    PubMed

    Brix, Johannes

    2010-01-01

    The first set of legislation for doctors in Denmark was conditional on a national need to regulate the conditions of the pharmaceutical and medical professions. By request of the king, this legislation, which came into force in 1672, was made by doctors residing in Denmark. These doctors had all been educated at foreign universities where the existing legislation had Roger II's and Friedrich II's legislation from the 12th and 13th centuries' South Italy as its source of inspiration. Thus, it is reasonable to presume that the doctors who participated in the making of the Danish legislation were familiar with this legislation. A translation into Danish of Roger II's and Friedrich II's sections regarding the work of a doctor has been made in order to be able to compare it with the content of the Danish set of legislation from 1672. The result of this comparison is that there are so many similarities that there can hardly be any doubt about the fact that the medieval legislation has been used as source for the Danish legislation from 1672.

  9. Mitochondrial Genetic Diversity of Eurasian Red Squirrels (Sciurus vulgaris) from Denmark.

    PubMed

    Madsen, Corrie L; Vilstrup, Julia T; Fernández, Ruth; Marchi, Nina; Håkansson, Bo; Krog, Mogens; Asferg, Tommy; Baagøe, Hans; Orlando, Ludovic

    2015-01-01

    Melanistic Eurasian red squirrels Sciurus vulgaris are commonly found on the Danish island of Funen. They are thought to represent native Danish squirrel types and are presently under threat from admixture with introduced red squirrels. In response, a conservation program was started in 2009 that involves the translocation of melanistic squirrels from Funen to the squirrel-free island of Langeland. Using mitochondrial DNA of 101 historical and modern samples from throughout Denmark, we assess for the first time population structure and mitochondrial genetic diversity of Danish squirrels compared to its larger pan-Eurasian distribution. We find that Danish squirrels have low levels of genetic diversity, especially melanistic individuals. Bayesian skyline reconstructions show that Danish squirrels have most probably experienced a severe bottleneck within the last 200 years. Also, fine-scale genetic structure was found between squirrels from the regions of Funen, Zealand and Jutland, which mimics the insular geography of Denmark. Additional nuclear DNA analyses will be required to determine the precise admixture levels between original Danish and introduced squirrels and to locate unmixed candidate populations for specific conservation efforts.

  10. First report of Eucoleus boehmi in red foxes (Vulpis vulpis) in Denmark, based on coprological examination.

    PubMed

    Al-Sabi, Mohammad Nafi Solaiman; Kapel, Christian Moliin Outzen

    2013-12-01

    Red foxes can be infected with diverse range of parasite species that can be transmitted to humans and pet animals, and the differential diagnosis is essential for veterinary and zoonotic risk assessment. In the present study, faecal flotation and microscopy of parasite eggs was done on 31 foxes originating from two distant localities in Denmark, the city of Copenhagen in the north east part of the island Zealand and from the southern part of the peninsular Jutland. In total, eggs of Eucoleus boehmi were recovered from a surprisingly high number of foxes (n = 22 samples; 71%). The findings represent the first observations of E. boehmi in Denmark, which is likely an overlooked infection of the upper respiratory tract of red foxes, which can be also found in other canids. Several morphological features of the eggs of E. boehmi can be used to distinguish it from other the closely related trichuroid eggs. Detecting cardiopulmonary parasites by faecal examination can be indicative of the presence of cardiopulmonary parasites based on the more sensitive post mortem analysis.

  11. Genetically distinct isolates of Spirocerca sp. from a naturally infected red fox (Vulpes vulpes) from Denmark.

    PubMed

    Al-Sabi, Mohammad Nafi Solaiman; Hansen, Mette Sif; Chriél, Mariann; Holm, Elisabeth; Larsen, Gitte; Enemark, Heidi Larsen

    2014-09-15

    Spirocerca lupi causes formation of nodules that may transform into sarcoma in the walls of aorta, esophagus and stomach of infected canids. In February 2013, post mortem examination of a red fox (Vulpes vulpes) hunted in Denmark revealed the presence of several nodules containing adult worms of Spirocerca sp. in the stomach and the omentum. The nodules largely consisted of fibrous tissue with infiltration of mononuclear cells, neutrophilic granulocytes and macrophages with hemosiderin deposition. Parasitological examination by three copromicroscopic methods, sedimentation, flotation with saturated sugar-salt solution, and sieving failed to detect eggs of Spirocerca sp. in feces collected from the colon. This is the first report of spirocercosis in Denmark, and may have been caused by a recent introduction by migrating paratenic or definitive host. Analysis of two overlapping partial sequences of the cox1 gene, from individual worms, revealed distinct genetic variation (7-9%) between the Danish worms and isolates of S. lupi from Europe, Asia and Africa. This was confirmed by phylogenetic analysis that clearly separated the Danish worms from other isolates of S. lupi. The distinct genetic differences of the current worms compared to other isolates of S. lupi may suggest the presence of a cryptic species within Spirocerca.

  12. Groundwater monitoring in Denmark: characteristics, perspectives and comparison with other countries

    NASA Astrophysics Data System (ADS)

    Jørgensen, Lisbeth Flindt; Stockmarr, Jens

    2009-06-01

    More than 99% of water use in Denmark is based on groundwater. Denmark has had a comprehensive national groundwater-monitoring programme since 1988 based on 74 well catchment areas and six small agricultural catchments with more than 1,500 screens at different depths for regular, mostly annual, water quality sampling. In addition, water samples from 10,000 abstraction wells are analysed every 3-5 years. The water is analysed for main components, inorganic trace elements, organic micro pollutants, and pesticides and their metabolites. A unique feature is the 20-year time-series data of inorganic pollutants. Groundwater modelling supports traditional monitoring to improve the conceptual geological understanding and to assess the quantitative status and the interaction between groundwater and surface water. The programme has been continuously adjusted to incorporate new knowledge from research programmes and meet new policy demands, currently the European Union Water Framework Directive, particularly with respect to an increased focus on quantitative aspects and on the groundwater/surface water interaction. The strengths and weaknesses of the Danish programme are assessed and compared with other national groundwater-monitoring programmes. Issues discussed include: strategic considerations for monitoring design, the link between research and monitoring, and adoption of responses to climate changes.

  13. Governing Health Care through Free Choice: Neoliberal Reforms in Denmark and the United States.

    PubMed

    Larsen, Lars Thorup; Stone, Deborah

    2015-10-01

    We compare free choice reforms in Denmark and the United States to understand what ideas and political forces could generate such similar policy reforms in radically different political contexts. We analyze the two cases using our own interpretation of neoliberalism as having "two faces." The first face seeks to expand private markets and shrink the public sector; the second face seeks to strengthen the public sector's capacity to govern through incentives and competition. First, we show why these two most-different cases offer a useful comparison to understand similar policy tools. Second, we develop our theoretical framework of the two faces of neoliberalism. Third, we examine Denmark's introduction of a free choice of hospitals in 2002, a policy that for the first time allowed some patients to receive care either in a public hospital outside their local area or in a private hospital. Fourth, we examine the introduction of free choice among private managed care plans into the US Medicare program in 1997. We show how policy makers in both countries used neoliberal reform as a mechanism to make their public health care sectors governable. Fifth, on the basis of our analysis, we draw five lessons about neoliberal policy reforms.

  14. Series of Norovirus Outbreaks Caused by Consumption of Green Coral Lettuce, Denmark, April 2016

    PubMed Central

    Müller, Luise; Rasmussen, Lasse Dam; Jensen, Tenna; Schultz, Anna Charlotte; Kjelsø, Charlotte; Barnadas, Celine; Sigsgaard, Kim; Larsen, Anne Ribert; Widstrup Jensen, Carl; Jeppesen, Simon; Uhrbrand, Katrine; Hove, Nikolas; Mølbak, Kåre; Ethelberg, Steen

    2016-01-01

    Introduction: In early April 2016, an unusual high number of point-source outbreaks of gastrointestinal disease were reported to occur in Denmark. Methods: Outbreaks were individually investigated. Two analytical studies were performed. Patient stool samples collected and analysed; positive stool samples were sequenced over the polymerase and/or capsid gene areas. Implicated lettuce heads were collected and analysed for the presence of norovirus. Foods were traced-back and traced-forward and international alert systems applied. Results: A total of 23 linked point-source outbreaks occurred over the course of one week. Fresh green coral lettuce (Lollo Bionda lettuce) had been consumed in all settings. In a cohort study including 234 participants a dish containing green lettuce was associated with illness. Norovirus of Genogroup I (GI) was detected in samples from 28 patients comprising eight of the outbreaks. Sequencing showed GI.P2-GI.2. GI norovirus was detected in one of 20 examined lettuce heads. All lettuce consumed was supplied by the same packer who in turn had bought the lettuce from a wholesaler in France. The two lots of lettuce came from two different growers in different parts of France. Discussion: Green coral lettuce produced in France was found to have caused a large series of linked norovirus outbreaks in Denmark as established by a number of lines of evidence. A similar incidence occurred in 2010. Fresh lettuce increasingly appear to be a risk food for norovirus infections. PMID:27803839

  15. Concentrations of anticoagulant rodenticides in stoats Mustela erminea and weasels Mustela nivalis from Denmark.

    PubMed

    Elmeros, Morten; Christensen, Thomas Kjær; Lassen, Pia

    2011-05-15

    Anticoagulant rodenticides are widely used to control rodent populations but they also pose a risk of secondary poisoning in non-target predators. Studies on anticoagulant rodenticide exposure of non-target species have mainly reported on frequency of occurrence. They have rarely analyzed variations in residue concentrations. We examine the occurrence and concentrations of five anticoagulant rodenticides in liver tissue from 61 stoats (Mustela erminea) and 69 weasels (Mustela nivalis) from Denmark. Anticoagulant rodenticides were detected in 97% of stoats and 95% of weasels. 79% of the animals had detectable levels of more than one substance. Difenacoum had the highest prevalence (82% in stoats and 88% in weasels) but bromadiolone was detected in the highest concentrations in both stoat (1.290 μg/g ww) and weasel (1.610 μg/g ww). Anticoagulant rodenticide concentrations were highest during autumn and winter and varied with sampling method. Anticoagulant rodenticide concentrations were higher in stoats and weasels with unknown cause of death than in specimens killed by physical trauma. There was a negative correlation between anticoagulant rodenticide concentrations and body condition. Our results suggest that chemical rodent control in Denmark results in an extensive exposure of non-target species and may adversely affect the fitness of some stoats and weasels.

  16. A quantitative analysis of biodiversity and the recreational value of potential national parks in Denmark.

    PubMed

    Larsen, Frank Wugt; Petersen, Anders Højgård; Strange, Niels; Lund, Mette Palitzsch; Rahbek, Carsten

    2008-05-01

    Denmark has committed itself to the European 2010 target to halt the loss of biodiversity. Currently, Denmark is in the process of designating larger areas as national parks, and 7 areas (of a possible 32 larger nature areas) have been selected for pilot projects to test the feasibility of establishing national parks. In this article, we first evaluate the effectiveness of the a priori network of national parks proposed through expert and political consensus versus a network chosen specifically for biodiversity through quantitative analysis. Second, we analyze the potential synergy between preserving biodiversity in terms of species representation and recreational values in selecting a network of national parks. We use the actual distribution of 973 species within these 32 areas and 4 quantitative measures of recreational value. Our results show that the 7 pilot project areas are not significantly more effective in representing species than expected by chance and that considerably more efficient networks can be selected. Moreover, it is possible to select more-effective networks of areas that combine high representation of species with high ranking in terms of recreational values. Therefore, our findings suggest possible synergies between outdoor recreation and biodiversity conservation when selecting networks of national parks. Overall, this Danish case illustrates that data-driven analysis can not only provide valuable information to guide the decision-making process of designating national parks, but it can also be a means to identify solutions that simultaneously fulfill several goals (biodiversity preservation and recreational values).

  17. Mesoscale mixing of the Denmark Strait Overflow in the Irminger Basin

    NASA Astrophysics Data System (ADS)

    Koszalka, Inga M.; Haine, Thomas W. N.; Magaldi, Marcello G.

    2017-04-01

    The Denmark Strait Overflow (DSO) is a major export route for dense waters from the Nordic Seas forming the lower limb of the Atlantic Meridional Overturning Circulation, an important element of the climate system. Mixing processes along the DSO pathway influence its volume transport and properties contributing to the variability of the deep overturning circulation. They are poorly sampled by observations, however, which hinders development of a proper DSO representation in global circulation models. We employ a high resolution regional ocean model of the Irminger Basin to quantify impact of the mesoscale flows on DSO mixing focusing on geographical localization and the time-modulation of water property changes. The model reproduces the observed bulk warming of the DSO plume 100-200 km downstream of the Denmark Strait sill. It also reveals that mesoscale variability of the overflow ('DSO-eddies', of 20-30 km extent and a time scale of 2-5 day) modulates water property changes and turbulent mixing, diagnosed with the vertical shear of horizontal velocity and the eddy heat flux divergence. The space-time localization of the DSO mixing and warming and the role of coherent mesoscale structures should be explored by turbulence measurements and factored into the coarse circulation models.

  18. Integrating Art.

    ERIC Educational Resources Information Center

    BCATA Journal for Art Teachers, 1991

    1991-01-01

    These articles focus on art as a component of interdisciplinary integration. (1) "Integrated Curriculum and the Visual Arts" (Anna Kindler) considers various aspects of integration and implications for art education. (2) "Integration: The New Literacy" (Tim Varro) illustrates how the use of technology can facilitate…

  19. Experiences gained from implementing mandatory buffer strips in Denmark: how can we enhance their ecosystem services?

    NASA Astrophysics Data System (ADS)

    Kronvang, Brian; Hoffmann, Carl Christian; Baattrup-Pedersen, Annette; Hille, Sandra; Rubæk, Gitte; Heckrath, Goswin; Gertz, Flemming; Jensen, Henning; Feuerback, Peter; Strand, John; Stutter, Marc

    2015-04-01

    The Danish Parliament adopted in June 2012 a Buffer Strip Act that required 10 m mandatory buffer strips (BSs) to be established along all watercourses and lakes with a surface area greater than 100 m2 from 1st September 2012. The main reasons for deploying BSs was to reduce nitrate-N leaching and phosphorus (P) loss via surface runoff from adjoining fields from the approximately 50,000 ha of BSs as no farming activities were allowed in the BS concerning use of fertilizer, spreading of manure, spraying with pesticides, etc. Reductions in nutrient losses to watercourses are needed for minimizing the eutrophication effects in lakes and coastal waters. Buffer strips are among the most well studied and frequently adapted mitigation measure for reducing sediment and P losses to surface waters via surface runoff. It has, however, been questioned if BSs can also reduce N losses. The international literature gives an overwhelming support to their functioning for reduction in sediment and especially particulate P losses. However, their functioning for dissolved P and nitrogen is more questionable when comparing studies from the international literature. In Denmark, many farmers were against the introduction of BSs as a general mitigation measure for several reasons. The most used argument in the public debate was that BSs in general are not very efficient for reducing N and P losses to surface waters which was originally the argument behind the BS Act from the Ministries of Environment and Food and Agriculture. A desk study had been made prior to the adaptation of the law that showed 10 m BSs to be able to reduce the N loading with 40-50 kg N ha-1 of BS and 0.04-0.4 kg P ha-1 BS. The total reduction from the BSs established in Denmark in 2012 would then amount to 2,000-2,500 tonnes N and 2-20 tonnes P. The intense public debate in Denmark made the Parliament to adopt a new BS law in June 2014 to be implemented in August 2014 that reduced the total areas with mandatory BSs

  20. Capacity Building: Data- and Research-Informed Development of Schools and Teaching Practices in Denmark and Norway

    ERIC Educational Resources Information Center

    Qvortrup, Lars

    2016-01-01

    Based on experiences from a number of large scale data- and research-informed school development projects in Denmark and Norway, led by the author, three hypotheses are discussed: that an effective way of linking research and practice is achieved (1) using a capacity building approach, that is, to collaborate in the practical school context…

  1. Neo-Liberalism and Universal State Education: The Cases of Denmark, Norway and Sweden 1980-2011

    ERIC Educational Resources Information Center

    Wiborg, Susanne

    2013-01-01

    This article investigates neo-liberal policy on education in Denmark, Norway and Sweden. Traditionally, the edifice of the education system in these Scandinavian countries has been built on egalitarian values, but over the last 20 years they have increasingly adopted market-led reforms of education. The extent of neo-liberal policy varies between…

  2. Metalinguistic Awareness and Academic Achievement in a Linguistically Diverse School Setting: A Study of Lower Secondary Pupils in Denmark

    ERIC Educational Resources Information Center

    Spellerberg, Stine Marie

    2016-01-01

    This study focuses on metalinguistic awareness (MLA) and its relation to academic achievement for mono-, bi- and multilingual adolescents in Denmark. While MLA is one of several cognitive measures positively related to bilingualism and bilingualism is associated with academic advantages, Danish bi-/multilingual pupils appear not to benefit from…

  3. Training in the Motor Vehicle Repair and Sales Sector in Denmark. Report for the FORCE Programme. First Edition.

    ERIC Educational Resources Information Center

    Knoblauch, Jan; And Others

    Training in Denmark's motor vehicle repair and sales sector was examined in a study that included the following approaches: review of the sector's structure/characteristics, institutional/social context, changing conditions and their implications for skill requirements and training, and available initial and continuing vocational education and…

  4. Discrepancies in listed adverse drug reactions in pharmaceutical product information supplied by the regulatory authorities in Denmark and the USA.

    PubMed

    Eriksson, Robert; Aagaard, Lise; Jensen, Lars Juhl; Borisova, Liza; Hørlück, Dorte; Brunak, Søren; Hansen, Ebba Holme

    2014-06-01

    Pharmaceutical product information (PI) supplied by the regulatory authorities serves as a source of information on safe and effective use of drugs. The objectives of this study were to qualitatively and quantitatively compare PIs for selected drugs marketed in both Denmark and the USA with respect to consistency and discrepancy of listed adverse drug reaction (ADR) information. We compared individual ADRs listed in PIs from Denmark and the USA with respect to type and frequency. Consistency was defined as match of ADRs and of ADR frequency or match could not be ruled out. Discrepancies were defined as ADRs listed only in one country or listed with different frequencies. We analyzed PIs for 40 separate drugs from ten therapeutic groups and assigned the 4003 identified ADRs to System Organ Classes (Medical Dictionary for Regulatory Activities [MedDRA] terminology). Less than half of listed ADRs (n = 1874; 47%) showed consistency. Discrepancies (n = 2129; 53%) were split into ADRs listed only in the USA (n = 1558; 39%), ADRs listed only in Denmark (n = 325; 8%) and ADRs listed with different frequencies (n = 246; 6%). The majority of listed ADRs were of the type "gastrointestinal disorders" and "nervous system disorders". Our results show great differences in PIs for drugs approved in both Denmark and the USA illuminating concerns about the credibility of the publicly available PIs. The results also represent an argument for further harmonization across borders to improve consistency between authority-supplied information.

  5. Mycobacterium chimaera in Heater-Cooler Units in Denmark Related to Isolates from the United States and United Kingdom.

    PubMed

    Svensson, Erik; Jensen, Elsebeth Tvenstrup; Rasmussen, Erik Michael; Folkvardsen, Dorte Bek; Norman, Anders; Lillebaek, Troels

    2017-03-01

    Mycobacterium chimaera was present at high rates (>80%) in heater-cooler units (HCUs) from all 5 thoracic surgery departments in Denmark. Isolates were clonal to HCU-associated isolates from the United States (including some from patients) and United Kingdom. However, M. chimaera from 2 brands of HCU were genetically distinct.

  6. The First Sourcebook on Nordic Research in Mathematics Education: Norway, Sweden, Iceland, Denmark and Contributions from Finland.

    ERIC Educational Resources Information Center

    Sriraman, Bharath, Ed.; Bergsten, Christer, Ed.; Goodchild, Simon, Ed.; Palsdottir, Gudbjorg, Ed.; Sondergaard, Bettina Dahl, Ed.; Haapasalo, Lenni, Ed.

    2010-01-01

    The First Sourcebook on Nordic Research in Mathematics Education: Norway, Sweden, Iceland, Denmark and contributions from Finland provides the first comprehensive and unified treatment of historical and contemporary research trends in mathematics education in the Nordic world. The book is organized in sections co-ordinated by active researchers in…

  7. Mycobacterium chimaera in Heater–Cooler Units in Denmark Related to Isolates from the United States and United Kingdom

    PubMed Central

    Jensen, Elsebeth Tvenstrup; Rasmussen, Erik Michael; Folkvardsen, Dorte Bek; Norman, Anders; Lillebaek, Troels

    2017-01-01

    Mycobacterium chimaera was present at high rates (>80%) in heater–cooler units (HCUs) from all 5 thoracic surgery departments in Denmark. Isolates were clonal to HCU-associated isolates from the United States (including some from patients) and United Kingdom. However, M. chimaera from 2 brands of HCU were genetically distinct. PMID:28035898

  8. Socio-Cultural Innovation through and by Public Libraries in Disadvantaged Neighbourhoods in Denmark: Concepts and Practices

    ERIC Educational Resources Information Center

    Delica, Kristian; Elbeshausen, Hans

    2013-01-01

    Introduction: Our paper describes three examples of how public libraries in at-risk-neighbourhoods have worked with social innovations in order to develop and strengthen their services for minority groups. The libraries were chosen because they are frontrunners in the field of cultural diversity and social inclusion in Denmark. Method: The…

  9. The Role of Learning and Career Guidance for Managing Mid-Career Transitions--Comparing Germany and Denmark

    ERIC Educational Resources Information Center

    Haasler, Simone R.; Barabasch, Antje

    2015-01-01

    In Germany and Denmark, the systems of further education and career guidance are well developed, offering a wide range of services and learning opportunities for targeted, specific and also general skills development. Based on an empirical study with mid-career individuals in both countries, the article investigates how the different systems…

  10. National Reading Tests in Denmark, Norway, and Sweden: A Comparison of Construct Definitions, Cognitive Targets, and Response Formats

    ERIC Educational Resources Information Center

    Tengberg, Michael

    2017-01-01

    Reading comprehension tests are often assumed to measure the same, or at least similar, constructs. Yet, reading is not a single but a multidimensional form of processing, which means that variations in terms of reading material and item design may emphasize one aspect of the construct at the cost of another. The educational systems in Denmark,…

  11. Exchange Program Teenagers Compare Life in Denmark and the U.S.A. Occasional Papers in Intercultural Learning No. 10.

    ERIC Educational Resources Information Center

    Bresee, Dana E.

    Thirty teenage exchange students from Denmark and the United States were interviewed concerning the differences they perceived in the two cultures. Salient differences were cited in the domains of family rules, education and schools, use of alcohol, romantic relationships and sexuality, communication and friendships, ethnic differences and…

  12. National Stereotypes and Language Attitudes: The Perception of British, American, and Australian Language and Culture in Denmark.

    ERIC Educational Resources Information Center

    Ladegaard, Hans J.

    1998-01-01

    Studied stereotyped reactions to English accents and cultures among Danish secondary school students in Denmark. In choice of preference of Received Pronunciation (RP), Scottish English, Australian English, Cockney English, and Standard American English, RP was found to be unsurpassed prestige variety in this Danish context. It was rated favorably…

  13. Summary of project TOR: delineation of a stepwise, sharp, deep lithosphere transition across Germany Denmark Sweden

    NASA Astrophysics Data System (ADS)

    Gregersen, S.; Voss, P.; TOR Working Group

    2002-12-01

    Project Tor ( Teleseismic Tomography across the Tornquist Zone in Germany-Denmark-Sweden) is now producing results. We are able to detect very significant deep lithosphere differences, and we can now discuss the sharpness laterally. In 1996-1997, our 120 seismographs constituted the largest seismic antenna ever in Europe. The Tor area was chosen along a well-studied crustal profile of an earlier project, and the inversion efforts are concentrated on the deep lithosphere and asthenosphere differences to depths around 300 km. The Tor investigation can be called two-and-a-half-dimensional, as it has a 900-km profile length with 100 km width plus a few seismographs off the profile. The Tor data have been subjected to P-wave travel time tomography, surface wave and receiver function analysis as well as anisotropy and scattering measurements. Through ray tracing in a compiled crustal model and subtraction of the modelled travel time anomalies, the influence of the lower lithosphere/asthenosphere on the seismic rays from distant earthquakes is being established. Travel time tomography results confirm very large lateral lithosphere differences of 4-6% in P-wave velocity. For several events of the large data base, it is demonstrated that the observed P-wave travel time anomalies of 1-2 s can be divided almost equally between known crustal effects and lower lithosphere/asthenosphere differences, which then must account for about 1 s of the travel time differences. The transition is interpreted to be sharp and steep in two places. It goes all the way through the lithosphere at the northern rim of the Tornquist Zone near the border between Sweden and Denmark, and here the lithosphere difference is large. A smaller lithosphere difference is found near the southern edge of the Ringkøbing-Fyn High just north of the border between Denmark and Germany. Also, this transition is sharp and steep, and goes all through the lithosphere. These two sharp transitions divide the Tor region

  14. Stress and distress in migration: problems and resources of Turkish women in Denmark.

    PubMed

    Mirdal, G M

    1984-01-01

    Data collected through interviews with 72 Turkish female immigrants to Denmark show that migration and the inevitable confrontation with an unfamiliar cultural mileu, create several stress producing situations, which they are unable to cope due to their multiple disadvantage of being poor, uneducated, alien and female. Turkish women began arriving in Denmark after 1973, in order to join male members of their families, when Denmark began experiencing economic recession and rising unemployment. This was responsible for the lukewarm reception they faced in their host country, even from their own relatives. A feeling of uprootedness is common in these women, who, leaving behind the security of their their own society, are constantly exposed to behavior patterns that appear to be in sharp contrast to their own. An unfamiliarity with the implicit structure of the society and rules of conduct can be threatening. Having a job outside the home creates the double burden of working to earn a living and having to take full responsibility for children and the household. On the other hand, not having a job creates an excess of leisure time, due to the availability of time saving gadgets, which is spent indoors with no meanigful activities. Lack of mobility compounds the situation. While proximity to other Turks inbitits freedom for fear of criticism, staying away brings loneliness. Changing concepts of sex roles can be disruptive, especially when roles they are brought up to believe are theirs, are no longer needed. As accompanying wives, they are excessively dependent on their husbands, and are more isolated and overwoked than they would have been in their homeland. All these factors help render the women extremely powerless. The women interviewed attributed their complaints, physical or emotional, to their state as immigrants. Women's complaints, especially if they are psychological in nature, lead to the danger of the women being labelled mentally ill. Despite their general

  15. A flexible hydrological warning system in Denmark for real-time surface water and groundwater simulations

    NASA Astrophysics Data System (ADS)

    He, Xin; Stisen, Simon; Wiese, Marianne B.; Jørgen Henriksen, Hans

    2015-04-01

    In Denmark, increasing focus on extreme weather events has created considerable demand for short term forecasts and early warnings in relation to groundwater and surface water flooding. The Geological Survey of Denmark and Greenland (GEUS) has setup, calibrated and applied a nationwide water resources model, the DK-Model, primarily for simulating groundwater and surface water flows and groundwater levels during the past 20 years. So far, the DK-model has only been used in offline historical and future scenario simulations. Therefore, challenges arise in operating such a model for online forecasts and early warnings, which requires access to continuously updated observed climate input data and forecast data of precipitation, temperature and global radiation for the next 48 hours or longer. GEUS has a close collaboration with the Danish Meteorological Institute in order to test and enable this data input for the DK model. Due to the comprehensive physical descriptions of the DK-Model, the simulation results can potentially be any component of the hydrological cycle within the models domain. Therefore, it is important to identify which results need to be updated and saved in the real-time mode, since it is not computationally economical to save every result considering the heavy load of data. GEUS have worked closely with the end-users and interest groups such as water planners and emergency managers from the municipalities, water supply and waste water companies, consulting companies and farmer organizations, in order to understand their possible needs for real time simulation and monitoring of the nationwide water cycle. This participatory process has been supported by a web based questionnaire survey, and a workshop that connected the model developers and the users. For qualifying the stakeholder engagement, GEUS has selected a representative catchment area (Skjern River) for testing and demonstrating a prototype of the web based hydrological warning system at the

  16. Awareness of cancer symptoms and anticipated patient interval for healthcare seeking. A comparative study of Denmark and Sweden.

    PubMed

    Hvidberg, Line; Lagerlund, Magdalena; Pedersen, Anette F; Hajdarevic, Senada; Tishelman, Carol; Vedsted, Peter

    2016-07-01

    Background Recent epidemiologic data show that Denmark has considerably poorer survival from common cancers than Sweden. This may be related to a lower awareness of cancer symptoms and longer patient intervals in Denmark than in Sweden. The aims of this study were to: 1) compare population awareness of three possible symptoms of cancer (unexplained lump or swelling, unexplained bleeding and persistent cough or hoarseness); 2) compare anticipated patient interval when noticing any breast changes, rectal bleeding and persistent cough; and 3) examine whether potential differences were noticeable in particular age groups or at particular levels of education in a Danish and Swedish population sample. Method Data were derived from Module 2 of the International Cancer Benchmarking Partnership. Telephone interviews using the Awareness and Beliefs about Cancer measure were conducted in 2011 among 3000 adults in Denmark and 3070 adults in Sweden. Results Danish respondents reported a higher awareness of two of three symptoms (i.e. unexplained lump or swelling and persistent cough or hoarseness) and a shorter anticipated patient interval for two of three symptoms studied (i.e. any breast changes and rectal bleeding) than Swedish respondents. Differences in symptom awareness and anticipated patient interval between these countries were most pronounced in highly educated respondents. Conclusion Somewhat paradoxically, the highest awareness of symptoms of cancer and the shortest anticipated patient intervals were found in Denmark, where cancer survival is lower than in Sweden. Thus, it appears that these differences in symptom awareness and anticipated patient interval do not help explain the cancer survival disparity between Denmark and Sweden.

  17. Framing (implicitly) matters: the role of religion in attitudes toward immigrants and Muslims in Denmark.

    PubMed

    Anderson, Joel; Antalíková, Radka

    2014-12-01

    Denmark is currently experiencing the highest immigration rate in its modern history. Population surveys indicate that negative public attitudes toward immigrants actually stem from attitudes toward their (perceived) Islamic affiliation. We used a framing paradigm to investigate the explicit and implicit attitudes of Christian and Atheist Danes toward targets framed as Muslims or as immigrants. The results showed that explicit and implicit attitudes were more negative when the target was framed as a Muslim, rather than as an immigrant. Interestingly, implicit attitudes were qualified by the participants' religion. Specifically, analyses revealed that Christians demonstrated more negative implicit attitudes toward immigrants than Muslims. Conversely, Atheists demonstrated more negative implicit attitudes toward Muslims than Atheists. These results suggest a complex relationship between religion, and implicit and explicit prejudice. Both the religious affiliation of the perceiver and the perceived religious affiliation of the target are key factors in social perception.

  18. Ten and a half years seroepidemiology of Mycoplasma pneumoniae infection in Denmark.

    PubMed Central

    Lind, K.; Bentzon, M. W.

    1991-01-01

    The study was based on a computerized card index of 9161 patients who had at least one positive blood specimen in the Mycoplasma pneumoniae complement fixation test. A total of 12,562 specimens from these patients had been sent to Statens Seruminstitut from hospitals and general practitioners during a 10.5-year period. The period encompassed a previously described endemic period in a 30-year study of the epidemiological pattern of M. pneumoniae infection in Denmark. The serological data presented support the hypothesis advanced here that a more than sixfold increase of children in day care might have contributed to a change in the epidemiological pattern. The correlation between age and level of specific antibodies, as well as persistence of seropositivity, were also investigated. PMID:1908784

  19. Response of the Denmark Strait overflow to Nordic Seas heat loss

    NASA Astrophysics Data System (ADS)

    Grist, Jeremy P.; Josey, Simon A.; Sinha, Bablu; Blaker, Adam T.

    2008-09-01

    The impact of extreme Nordic Seas heat loss on Denmark Strait (DS) dense water transport is examined in (1) control runs of the Hadley Centre HadCM3 and HadGEM1 coupled climate models and (2) perturbation experiments with the fast coupled model FORTE that allow heat flux effects to be isolated from wind stress. All three models show an approximately linear increase in southward DS transport of cold dense water with increasing Nordic Seas winter heat loss in the range -80 to -250 Wm-2. The propagation of the cold anomaly from the Nordic Seas source along a trajectory through the DS and into the Irminger Basin is also examined. A common response time is found with the strongest decrease in DS temperature occurring within 8-12 months of the heat loss signal. Our results show that Nordic Seas heat loss must be considered in addition to other processes in understanding DS variability.

  20. Family Nursing Therapeutic Conversations in Heart Failure Outpatient Clinics in Denmark: Nurses' Experiences.

    PubMed

    Voltelen, Barbara; Konradsen, Hanne; Østergaard, Birte

    2016-05-01

    As part of the Heart Failure Family Trial presently being conducted in Denmark, this qualitative process evaluation explored the perceptions of seven practicing cardiac nurses who offered family nursing therapeutic conversations (FNTC) to families in three heart failure outpatient clinics. FNTC were guided by the Calgary Family Assessment and Intervention Models. Data consisted of 34 case reports written by the nurses which documented the use of FNTC, including family responses to the FNTC. A focus group interview with the six of the nurses about their experience of offering FNTC was also conducted. Content analysis was performed using a combined deductive and inductive process. Nurses reported developing a distinct, closer, and more constructive relationship with the patients and their families and reported FNTC increased family bonding and strengthened family relationships. The nurses considered FNTC to be feasible interventions in the routine care provided in heart failure outpatient clinics.

  1. Modelling of transport and biogeochemical processes in pollution plumes: Vejen landfill, Denmark

    NASA Astrophysics Data System (ADS)

    Brun, Adam; Engesgaard, Peter; Christensen, Thomas H.; Rosbjerg, Dan

    2002-01-01

    A biogeochemical transport code is used to simulate leachate attenuation, biogeochemical processes, and development of redox zones in a pollution plume downstream of the Vejen landfill in Denmark. Calibration of the degradation parameters resulted in a good agreement with the observed distribution in the plume of a number of species, such as dissolved organic carbon (DOC), Fe 2+, NO 3-, HCO 3-, SO 42-, CH 4, and pH. The simulated redox zones agree with observations confirming that the Fe-reducing zone played an important role in the attenuation of the DOC plume. Effective first-order rate constants for every redox zone were determined giving DOC half-lives ranging from 100 to 1-2 days going from the methanogenic to the aerobic zone. The order of decrease in DOC half-lives from the anaerobic to the aerobic zone corresponds to findings at other landfills.

  2. [Radium therapy in a county hospital on the island of Mors, Denmark].

    PubMed

    Søgaard, Ib; Topp, Sven W

    2010-01-01

    In Denmark it was decided early in the 20th century that therapy with radium should be restricted to major centres in the three largest cities, Copenhagen, Aarhus and Odense. In the northern part of Jutland the chief surgeon of Nykøbing Mors Hospital, Jacob Nordentoft (1881-1954), had studied radium treatment in Hamburg with Albers-Schönberg and in Paris with Marie Curie, and he had used radium in his private clinic since 1910. Naturally he wanted to continue this when he became chief in Nykøbing in 1922. As he was denied this the 22,000 inhabitants of this small island in 1931 collected 28,790 Danish Crowns for him as a birthday present and afterwards he could buy 94 mg pure radium from Belgium. With this amount he established a Radium Centre which lasted for 30 years.

  3. United States and Denmark: different approaches to health care and family planning.

    PubMed

    David, H P; Morgall, J M; Osler, M; Rasmussen, N K; Jensen, B

    1990-01-01

    The findings of this study suggest that, compared to the United States, Danish health care policies and family planning services delivery systems are, in the aggregate, more conducive to the promotion of effective contraceptive practice, more instrumental in conveying information to high-risk groups, and more successful in reducing the incidence of unintended pregnancies and induced abortions. One of the major reasons for this difference may stem from the positive and nonambivalent climate of public opinion about sexuality in Denmark and the manner in which health care and family planning services are delivered to all segments of the population regardless of age, income, or location of residence. Research in reproductive behavior is greatly facilitated by the existence of automated population registers.

  4. A roller-like bird (Coracii) from the Early Eocene of Denmark

    PubMed Central

    Bourdon, Estelle; Kristoffersen, Anette V.; Bonde, Niels

    2016-01-01

    The fossil record of crown group birds (Neornithes) prior to the Cretaceous-Paleogene boundary is scarce and fragmentary. Early Cenozoic bird fossils are more abundant, but are typically disarticulated and/or flattened. Here we report the oldest roller (Coracii), Septencoracias morsensis gen. et sp. nov. (Primobucconidae), based on a new specimen from the Early Eocene (about 54 million years ago) Fur Formation of Denmark. The new fossil is a nearly complete, three-dimensionally preserved and articulated skeleton. It lies at the lower end of the size range for extant rollers. Salient diagnostic features of Septencoracias relative to other Coracii include the proportionally larger skull and the small, ovoid and dorsally positioned narial openings. Our discovery adds to the evidence that the Coracii had a widespread northern hemisphere distribution in the Eocene. Septencoracias is the oldest substantial record of the Picocoraciae and provides a reliable calibration point for molecular phylogenetic studies. PMID:27670387

  5. Heritability in political interest and efficacy across cultures: Denmark and the United States.

    PubMed

    Klemmensen, Robert; Hatemi, Peter K; Hobolt, Sara B; Skytthe, Axel; Nørgaard, Asbjørn S

    2012-02-01

    Interest in politics is important for a host of political behaviors and beliefs. Yet little is known about where political interest comes from. Most studies exploring the source of political interest focus on parental influences, economic status, and opportunity. Here, we investigate an alternative source: genetic transmission. Using two twin samples, one drawn from Denmark and the other from USA, we find that there is a high degree of heritability in political interest. Furthermore, we show that interest in politics and political efficacy share the same underlying, latent genetic factor. These findings add to the growing body of literature that documents political behaviors and attitudes as not simply the result of socialization, but also as part of an individual's genetically informed disposition.

  6. Application and development of IR techniques for building and construction sector in Denmark

    NASA Astrophysics Data System (ADS)

    Melballe, Jens A.

    1990-03-01

    In Denmark IR-techniques have found a widespend use in the Building and Construction sector. The applications include control of insulation level of buildings, district heating networks, transformer stations, electrical networks and water pipes in buildings, electrically heated floors, etc. In this paper is first described the Danish voluntary system for inspection of building insulation. This work is supervised by a government agency. Some examples are given on how these activities are carried out in practice. An important question is how to develop IR-techniques for new applications and how to transfer this knowledge for practical use. In this paper we describe how activities of this kind are carried out in cooperation with government bodies, research organizations and users of thermography. Important aspects discussed include the initialization of development projects, the financial aspects, the organization of projects of this kind and the technology transfer. Some examples are given from work of this kind.

  7. [Last resort? Some incidents in the history of psychosurgery in Denmark].

    PubMed

    Kragh, Jesper Vaczy

    2007-01-01

    In 1935 psychosurgery was invented in Portugal by Egas Moniz. A few years later the new therapy for psychiatric patients were introduced and widely used in Danish mental hospitals. Why did Danish psychiatrists utilize an uncertain and unsafe treatment, and what conditions contributed to the extensive use of psychosurgery in Denmark? To answer these questions, this article focuses on the large archives from the Directorate of the State Mental Hospitals and various mental hospitals in order to investigate the negotiations regarding psychosurgery. Especially the case notes from the State Mental Hospital in Vordingborg, a hospital with 850 beds in southern Zealand, give an insight into the doctors' considerations, when they contemplated on using psychosurgery. In the archive in Vordingborg 336 patient records from lobotomized patients have been found and subjected to statistical analysis in this article. The analysis of the patient records from Vordingborg and other state mental hospitals shows that the practise of lobotomy was a complex matter, and a number of different factors played a part in the wide use of the therapy in Denmark. Especially the dire conditions of the mental hospitals in the 1940s and 1950s made doctors consider psychosurgery a solution for the many patients living a miserable life in the back wards of the hospitals. Patients, who had spent years of their lives in the hospital's "disturbed wards", were particularly exposed to psychosurgery. In the patients records the most common indications for psychosurgery were "unruly" and "aggressive" behaviour, but other factors such as the patient's lengths of stay in the hospital, patients racked with pain, and lack of response to other somatic treatments could also prompt psychiatrists to employ lobotomy.

  8. National Automated Surveillance of Hospital-Acquired Bacteremia in Denmark Using a Computer Algorithm.

    PubMed

    Gubbels, Sophie; Nielsen, Jens; Voldstedlund, Marianne; Kristensen, Brian; Schønheyder, Henrik C; Ellermann-Eriksen, Svend; Engberg, Jørgen H; Møller, Jens K; Østergaard, Christian; Mølbak, Kåre

    2017-03-09

    BACKGROUND In 2015, Denmark launched an automated surveillance system for hospital-acquired infections, the Hospital-Acquired Infections Database (HAIBA). OBJECTIVE To describe the algorithm used in HAIBA, to determine its concordance with point prevalence surveys (PPSs), and to present trends for hospital-acquired bacteremia SETTING Private and public hospitals in Denmark METHODS A hospital-acquired bacteremia case was defined as at least 1 positive blood culture with at least 1 pathogen (bacterium or fungus) taken between 48 hours after admission and 48 hours after discharge, using the Danish Microbiology Database and the Danish National Patient Registry. PPSs performed in 2012 and 2013 were used for comparison. RESULTS National trends showed an increase in HA bacteremia cases between 2010 and 2014. Incidence was higher for men than women (9.6 vs 5.4 per 10,000 risk days) and was highest for those aged 61-80 years (9.5 per 10,000 risk days). The median daily prevalence was 3.1% (range, 2.1%-4.7%). Regional incidence varied from 6.1 to 8.1 per 10,000 risk days. The microorganisms identified were typical for HA bacteremia. Comparison of HAIBA with PPS showed a sensitivity of 36% and a specificity of 99%. HAIBA was less sensitive for patients in hematology departments and intensive care units. Excluding these departments improved the sensitivity of HAIBA to 44%. CONCLUSIONS Although the estimated sensitivity of HAIBA compared with PPS is low, a PPS is not a gold standard. Given the many advantages of automated surveillance, HAIBA allows monitoring of HA bacteremia across the healthcare system, supports prioritizing preventive measures, and holds promise for evaluating interventions. Infect Control Hosp Epidemiol 2017;1-8.

  9. Gastrointestinal parasites of cats in Denmark assessed by necropsy and concentration McMaster technique.

    PubMed

    Takeuchi-Storm, N; Mejer, H; Al-Sabi, M N S; Olsen, C S; Thamsborg, S M; Enemark, H L

    2015-12-15

    The large population of feral cats in Denmark may potentially transmit pathogens to household cats and zoonotic parasites to humans. A total of 99 euthanized cats; feral cats (n=92) and household cats with outdoor access (n=7), were collected from March to May 2014 from the Zealand region, Denmark. The sedimentation and counting technique (SCT) was used to isolate helminths and coproscopy was done by concentration McMaster technique (c-McMaster). Overall, 90.1% of the cats were infected and a total of 10 species were recorded by SCT: 5 nematode species: Toxocara cati (84.8%), Ollulanus tricuspis (13.1%), Aonchotheca putorii (7.1%), Paersonema spp. (3.0%), Strongyloides spp. (1.0%); 3 cestodes: Hydatigera taeniaeformis (36.4%), Mesocestoides sp. (3.0%), Dipylidium caninum (1.0%); and 2 trematodes: Cryptocotyle spp. (5.1%) and Pseudamphistomum truncatum (1.0%). O. tricuspis was the second most common gastrointestinal nematode of cats but had the highest intensity of infection. For T. cati, prevalence and worm burden were significantly higher in feral than household cats. No juvenile cats were infected with H. taeniaeformis, and age thus had a significant effect on prevalence and worm burdens of this species. Rural cats had a higher prevalence and worm burden of A. putorii than urban cats. By c-McMaster, ascarid, capillarid, strongylid or taeniid type eggs were found in 77.9% of the cats while Cystoisospora felis was found in 2.1%. The sensitivity of the c-McMaster was 82.5% for T. cati but 26.5% for taeniid eggs, using the SCT as gold standard. A positive correlation between faecal egg counts and worm burdens was seen for T. cati, but not for taeniid eggs (assumed to be H. taeniaeformis). Coprological examination also detected the eggs of extraintestinal Capillariidae species including Eucoleus aerophilus and Eucoleus boehmi, but further necropsy studies are needed to confirm these findings.

  10. Healthism in Denmark: State, market, and the search for a "Moral Compass".

    PubMed

    Kristensen, Dorthe Brogård; Lim, Ming; Askegaard, Søren

    2016-09-01

    This article focuses on contemporary responses to public health messages in Denmark, a country whose system of social welfare is, like that of the United Kingdom and the rest of Europe, undergoing increasing levels of marketization and privatization. Drawing primarily upon Robert Crawford's analysis of healthism as a neoliberal project, the aim of this article is to develop critical understandings of how individuals respond both bodily and emotionally to ideologies of health and the body in the context of a changing marketplace for the consumption of health and its messages. This article will analyze perceptions and practices of health in Denmark. The findings will then be discussed in relation to dimensions inspired by the work of Crawford, who regards "health" as a "super-value," an outcome of individual security strategies, and mode of citizenship in the marketplace. The article argues that Crawford's discussion does not fully capture the ways in which people use their bodies to valorize themselves. First, the perception of the state is perceived as being aligned with commercial interests. As a consequence, neither state- nor market-based (i.e. commercial health product and service providers) health advice is fully trusted. Instead, the opinions of non-market actors such as peers and friends as well as of alternative practitioners that are considered outside the market since they do not represent corporate interests become more attractive among citizen-consumers who are concerned about their health. The article concludes with a discussion of the implications of our findings for theorization of public health and health policy.

  11. High exposure rates of anticoagulant rodenticides in predatory bird species in intensively managed landscapes in Denmark.

    PubMed

    Christensen, Thomas Kjær; Lassen, Pia; Elmeros, Morten

    2012-10-01

    The extensive use of anticoagulant rodenticides (ARs) for rodent control has led to widespread secondary exposure in nontarget predatory wildlife species. We investigated exposure rates and concentrations of five ARs in liver samples from five raptors and six owls from Denmark. A total of 430 birds were analysed. ARs were detected in 84-100 % of individual birds within each species. Multiple AR exposure was detected in 73 % of all birds. Average number of substances detected in individual birds was 2.2 with no differences between owls and raptors. Difenacoum, bromadiolone, and brodifacoum were the most prevalent substances and occurred in the highest concentrations. Second-generation ARs made up 96 % of the summed AR burden. Among the six core species (sample size >30), summed AR concentrations were lower in rough-legged buzzard (Buteo lagopus) and long-eared owl (Asio otus) than in barn owl (Tyto alba), buzzard (B. buteo), kestrel (Falco tinnunculus), and tawny owl (Strix aluco). There was a strong tendency for seasonal variations in the summed AR concentration with levels being lowest during autumn, which is probably related to an influx of less-exposed migrating birds from northern Scandinavia during autumn. High hepatic AR residue concentrations (>100 ng/g wet weight), which have been associated with symptoms of rodenticide poisoning and increased mortality, were recorded high frequencies (12.9-37.4 %) in five of the six core species. The results suggest that the present use of ARs in Denmark, at least locally, may have adverse effects on reproduction and, ultimately, population status in some raptors and owls.

  12. Anoctamin 5 muscular dystrophy in Denmark: prevalence, genotypes, phenotypes, cardiac findings, and muscle protein expression.

    PubMed

    Witting, Nanna; Duno, Morten; Petri, Helle; Krag, Thomas; Bundgaard, Henning; Kober, Lars; Vissing, John

    2013-08-01

    Since the initial description in 2010 of anoctamin 5 deficiency as a cause of muscular dystrophy, a handful of papers have described this disease in cases of mixed populations. We report the first large regional study and present data on new aspects of prevalence, muscular and cardiac phenotypic characteristics, and muscle protein expression. All patients in our neuromuscular unit with genetically unclassified, recessive limb girdle muscular dystrophy (LGMD2), Miyoshi-type distal myopathy (MMD) or persistent asymptomatic hyperCK-emia (PACK) were assessed for mutations in the ANO5 gene. Genetically confirmed patients were evaluated with muscular and cardiopulmonary examination. Among 40 unclassified patients (28 LGMD2, 5 MMD, 7 PACK), 20 were homozygous or compound heterozygous for ANO5 mutations, (13 LGMD2, 5 MMD, 2 PACK). Prevalence of ANO5 deficiency in Denmark was estimated at 1:100.000 and ANO5 mutations caused 11 % of our total cohort of LGMD2 cases making it the second most common LGMD2 etiology in Denmark. Eight patients complained of dysphagia and 3 dated symptoms of onset in childhood. Cardiac examinations revealed increased frequency of premature ventricular contractions. Four novel putative pathogenic mutations were discovered. Total prevalence and distribution of phenotypes of ANO5 disease in a representative regional cohort are described for the first time. A high prevalence of ANO5 deficiency was found among patients with unclassified LGMD2 (46 %) and MMD (100 %). The high incidence of reported dysphagia is a new phenotypic feature not previously reported, and cardiac investigations revealed that ANO5-patients may have an increased risk of ventricular arrhythmia.

  13. Social disparities in diabetes care: a general population study in Denmark

    PubMed Central

    Heltberg, Andreas; Andersen, John Sahl; Kragstrup, Jakob; Siersma, Volkert; Sandholdt, Håkon; Ellervik, Christina

    2017-01-01

    Objective We investigated the association between socioeconomic factors and the attainment of treatment goals and pharmacotherapy in patients with type 2 diabetes in Denmark. Design A cross-sectional population study. Setting The municipality of Naestved, Denmark. Subjects We studied 907 patients with type 2 diabetes identified from a random sample of 21,205 Danish citizens. Main outcome measures The proportion of patients who were not achieving goals for diabetes care based on their HbA1c, LDL-cholesterol, blood pressure, and lifestyle, and the proportion of patients who were treated with antihypertensive and cholesterol- and glucose-lowering medication. Methods We investigated the association of the socioeconomic factors such as age, gender, education, occupation, income, and civil status and attainment of treatment goals and pharmacotherapy in logistic regression analyses. We investigated effect modification of cardiovascular disease and kidney disease. Results Middle age (40–65 years), low education level (i.e. basic schooling), and low household income (i.e. less than 21,400 € per year) were associated with nonattainment of goals for diabetes care. The association of socioeconomic factors with attainment of individual treatment goals varied. Patients with low socioeconomic status were more often obese, physically inactive, smoking, and had elevated blood pressure. Socioeconomic factors were not associated with treatment goals for hyperglycemia. Socioeconomic factors were inconsistently associated with pharmacotherapy. There was no difference in contacts to general practitioners according to SES. Conclusions In a country with free access to health care, the socioeconomic factors such as middle age, low education, and low income were associated with nonattainment of goals for diabetes care. Key points Middle age, low education, and low income were associated with nonattainment of goals for diabetes care, especially for lifestyle goals. Patients with low

  14. Providing medical care for undocumented migrants in Denmark: what are the challenges for health professionals?

    PubMed Central

    2011-01-01

    Background The rights of undocumented migrants are frequently overlooked. Denmark has ratified several international conventions recognizing the right to health care for all human beings, but has very scanty legislation and no existing policies for providing health care to undocumented migrants. This study focuses on how health professionals navigate and how they experience providing treatment for undocumented migrants in the Danish health care system. Methods The study was carried out as part of an EU-project on European Best Practices in Access, Quality and Appropriateness of Health Services for Immigrants in Europe (EUGATE). This presentation is based on 12 semi-structured interviews with general practitioners (9) and emergency room physicians (3) in Denmark. Results The emergency room physicians express that treatment of undocumented migrants is no different from the treatment of any other person. However, care may become more complicated due to lack of previous medical records and contact persons. Contrary to this, general practitioners explain that undocumented migrants will encounter formal barriers when trying to obtain treatment. Additional problems in the treatment of undocumented migrants include language issues, financial aspects for general practitioners, concerns about how to handle the situation including possibilities of further referrals, and an uncertainty as to whether to involve the police. Conclusions The health professionals in our study describe that undocumented migrants experience an unequal access to primary care facilities and that great uncertainties exist amongst health professionals as how to respond in such situations. The lack of official policies concerning the right to health care for undocumented migrants continue to pass on the responsibility to health professionals and, thereby, leaves it up to the individual to decide whether treatment can be obtained or not. PMID:21711562

  15. Integration, Resegregation and Integration Maintenance.

    ERIC Educational Resources Information Center

    Peterman, William A.

    Recent increases in black migration to the suburbs and the continuing existence of discrimination in housing have emphasized the issues of integration and resegregation in suburban municipalities. To prevent resegregation, many integrated municipalities have adopted integration maintenance measures such as efforts to inform people that racial…

  16. Integrated Wind Power Planning Tool

    NASA Astrophysics Data System (ADS)

    Rosgaard, M. H.; Giebel, G.; Nielsen, T. S.; Hahmann, A.; Sørensen, P.; Madsen, H.

    2012-04-01

    This poster presents the current state of the public service obligation (PSO) funded project PSO 10464, with the working title "Integrated Wind Power Planning Tool". The project commenced October 1, 2011, and the goal is to integrate a numerical weather prediction (NWP) model with purely statistical tools in order to assess wind power fluctuations, with focus on long term power system planning for future wind farms as well as short term forecasting for existing wind farms. Currently, wind power fluctuation models are either purely statistical or integrated with NWP models of limited resolution. With regard to the latter, one such simulation tool has been developed at the Wind Energy Division, Risø DTU, intended for long term power system planning. As part of the PSO project the inferior NWP model used at present will be replaced by the state-of-the-art Weather Research & Forecasting (WRF) model. Furthermore, the integrated simulation tool will be improved so it can handle simultaneously 10-50 times more turbines than the present ~ 300, as well as additional atmospheric parameters will be included in the model. The WRF data will also be input for a statistical short term prediction model to be developed in collaboration with ENFOR A/S; a danish company that specialises in forecasting and optimisation for the energy sector. This integrated prediction model will allow for the description of the expected variability in wind power production in the coming hours to days, accounting for its spatio-temporal dependencies, and depending on the prevailing weather conditions defined by the WRF output. The output from the integrated prediction tool constitute scenario forecasts for the coming period, which can then be fed into any type of system model or decision making problem to be solved. The high resolution of the WRF results loaded into the integrated prediction model will ensure a high accuracy data basis is available for use in the decision making process of the Danish

  17. Glacio-tectonic thrust and deformation structures in the Vejle Fjord, Denmark revealed by high-resolution subbottom-profile data

    NASA Astrophysics Data System (ADS)

    Andresen, Katrine Juul; Boldreel, Lars Ole; Bak Wahlgreen, Katrine; Seidenkrantz, Marit-Solveig; Røy, Hans; Nørmark, Egon; Brandbyge Ernstsen, Verner

    2016-04-01

    undisturbed build-out sequence can be observed to the north and in front of the thrust-belt probably representing meltwater sedimentation related to the retreat of the ice advance. Steeply inclined reflections observed c. 10 km northwest of the thrust-belt and within the inner parts of the fjord, indicate rapid and westward prograding deposition and filling of the fjord. Such rapid infill probably reflects sudden failure of temporary thresholds sheltering the inner parts of the fjord, i.e. large ice chunks left behind during ice retreats. Besides of documenting the intense glacio-tectonic deformation in the Vejle Fjord region, our study demonstrates the utility of integrating subbottom profiler data with already known information on ice movements from outcrops and shallow cores. The subbottom profiler data provides larger (longer and deeper) sectional views on for instance deformation and deposition complexes related to ice progressions and retreats and thus represents a very good supplement and valuable input to field mapping and outcrops studies concerned with the Quaternary and youngest geological evolution in Denmark.

  18. Wind Technology, Cost, and Performance Trends in Denmark, Germany, Ireland, Norway, the European Union, and the United States: 2007 - 2012; NREL (National Renewable Energy Laboratory)

    SciTech Connect

    Hand, Maureen

    2015-06-15

    This presentation provides a summary of IEA Wind Task 26 report on Wind Technology, Cost, and Performance Trends in Denmark, Germany, Ireland, Norway, the European Union, and the United States: 2007-2012

  19. Integrated Wind Power Planning Tool

    NASA Astrophysics Data System (ADS)

    Rosgaard, Martin; Giebel, Gregor; Skov Nielsen, Torben; Hahmann, Andrea; Sørensen, Poul; Madsen, Henrik

    2013-04-01

    This poster presents the current state of the public service obligation (PSO) funded project PSO 10464, with the title "Integrated Wind Power Planning Tool". The goal is to integrate a mesoscale numerical weather prediction (NWP) model with purely statistical tools in order to assess wind power fluctuations, with focus on long term power system planning for future wind farms as well as short term forecasting for existing wind farms. Currently, wind power fluctuation models are either purely statistical or integrated with NWP models of limited resolution. Using the state-of-the-art mesoscale NWP model Weather Research & Forecasting model (WRF) the forecast error is sought quantified in dependence of the time scale involved. This task constitutes a preparative study for later implementation of features accounting for NWP forecast errors in the DTU Wind Energy maintained Corwind code - a long term wind power planning tool. Within the framework of PSO 10464 research related to operational short term wind power prediction will be carried out, including a comparison of forecast quality at different mesoscale NWP model resolutions and development of a statistical wind power prediction tool taking input from WRF. The short term prediction part of the project is carried out in collaboration with ENFOR A/S; a Danish company that specialises in forecasting and optimisation for the energy sector. The integrated prediction model will allow for the description of the expected variability in wind power production in the coming hours to days, accounting for its spatio-temporal dependencies, and depending on the prevailing weather conditions defined by the WRF output. The output from the integrated short term prediction tool constitutes scenario forecasts for the coming period, which can then be fed into any type of system model or decision making problem to be solved. The high resolution of the WRF results loaded into the integrated prediction model will ensure a high accuracy

  20. Cancer patient pathways in Denmark as a joint effort between bureaucrats, health professionals and politicians--a national Danish project.

    PubMed

    Probst, Helene Bilsted; Hussain, Zubair Butt; Andersen, Ole

    2012-04-01

    In 2007 and 2008 Danish Cancer Patient Pathways for 32 cancer types were developed and afterwards implemented on a national scale. Often bureaucrats, health professionals and politicians look upon the health sector in different ways and work independent of each other. In Denmark, as indeed internationally, patient pathways are frequently developed solely by health professionals and the consequence may be major difficulties in implementing the pathways on a national scale. In this article we describe how national Danish Cancer Patient Pathways were developed with a consensus seeking model and the impact it has had on the health system. The model used in Denmark ensured involvement and cooperation between bureaucrats, health professionals and politicians and afterwards a successful national implementation. The Cancer Patient Pathways has significantly reduced waiting times which is thought to increase survival. This experience gives important input to the continuous challenges on how to implement evidence based medicine on a national scale and stipulates a model for this process.

  1. Genetic population structure of the prosobranch snail Potamopyrgus antipodarum (Gray) in Denmark using PCR-RAPD fingerprints.

    PubMed

    Jacobsen, R; Forbes, V E; Skovgaard, O

    1996-08-22

    Parthenogenetic species are often more widely distributed geographically than their sexual relatives. This success in colonizing can be explained either by dispersal of one or a few clones of wide physiological tolerance or by the distribution of many locally adapted clones. Here we test the hypothesis that successfully invading clones of Potamopyrgus antipodarum (Gray) are composed of a few broadly adapted genotypes by using polymerase chain reaction random amplified polymorphic DNA (PCR-RAPD) fingerprinting on six different populations of P. antipodarum from Denmark and three morphotypes of P. antipodarum from Britain. We detected two genotypes of P. antipodarum in six populations examined across Denmark using four decamer primers. The two genotypes were found to be morphologically and genetically indistinguishable from British P. antipodarum. In five of the six Danish populations only one genotype was found; at the remaining site, the two genotypes occurred sympatrically. The present study suggests that P. antipodarum successfully invaded Europe by the proliferation of very few clones.

  2. Farmer driven national monitoring of nitrogen concentrations in drainage water in Denmark

    NASA Astrophysics Data System (ADS)

    Piil, Kristoffer; Lemming, Camilla; Kolind Hvid, Søren; Knudsen, Leif

    2014-05-01

    Field drains are often considered to short circuit the hydrological cycle in agricultural catchments and lead to an increased risk of nitrogen loss to the environment. Because of increased regulation of agricultural practices due to catchment management plans, resulting from the implementation of the water frame directive, Danish farmers pushed for a large scale monitoring of nitrogen loss from field drains. Therefore, the knowledge centre for agriculture, Denmark, organized a three year campaign where farmers and local agricultural advisory centres collected water samples from field drains three to five times during the winter season. Samples were analysed for nitrate and total nitrogen. Combined, more than 600 drains were monitored over the three years. During the first two years of monitoring, average winter concentrations of total nitrogen ranged from 0.1 mg N L-1 to 31.1 mg N L-1, and the fraction of total nitrogen present as nitrate ranged from 0% to 100%. This variation is much larger than what is observed in the Danish national monitoring and assessment programme, which monitors only a few drains in selected catchments. Statistical analysis revealed that drainage water nitrogen concentrations were significantly correlated to the cropping system and the landscape type (high ground/lowlands/raised seabed) in which the monitored fields were situated. The average total nitrogen concentration was more than 2 mg N L-1 lower on raised seabed than on high ground, and the average fraction of total nitrogen present as nitrate was more than 20% lower. This indicates that substantial nitrate reduction occurs at or above the drain depth on raised sea flats, in particular in the north of Denmark. This inherent nitrogen retention on raised seabed is not taken into account in the current environmental regulation, nor in the first generation catchment management plans. The monitoring program demonstrated large variation in nitrogen concentrations in drainage water, in

  3. Large regional differences in incidence of arthroscopic meniscal procedures in the public and private sector in Denmark

    PubMed Central

    Hare, Kristoffer Borbjerg; Vinther, Jesper Høeg; Lohmander, L Stefan; Thorlund, Jonas Bloch

    2015-01-01

    Objectives A recent study reported a large increase in the number of meniscal procedures from 2000 to 2011 in Denmark. We examined the nation-wide distribution of meniscal procedures performed in the private and public sector in Denmark since different incentives may be present and the use of these procedures may differ from region to region. Setting We included data on all patients who underwent an arthroscopic meniscal procedure performed in the public or private sector in Denmark. Participants Data were retrieved from the Danish National Patient Register on patients who underwent arthroscopic meniscus surgery as a primary or secondary procedure in the years 2000 to 2011. Hospital identification codes enabled linkage of performed procedures to specific hospitals. Primary and secondary outcome measures Yearly incidence of meniscal procedures per 100 000 inhabitants was calculated with 95% CIs for public and private procedures for each region. Results Incidence of meniscal procedures increased at private and at public hospitals. The private sector accounted for the largest relative and absolute increase, rising from an incidence of 1 in 2000 to 98 in 2011. In 2011, the incidence of meniscal procedures was three times higher in the Capital Region than in Region Zealand. Conclusions Our study identified a large increase in the use of meniscal procedures in the public and private sector in Denmark. The increase was particularly conspicuous in the private sector as its proportion of procedures performed increased from 1% to 32%. Substantial regional differences were present in the incidence and trend over time of meniscal procedures. PMID:25712820

  4. Large-scale climate variability and its effects on mean temperature and flowering time of Prunus and Betula in Denmark

    NASA Astrophysics Data System (ADS)

    Gormsen, A. K.; Hense, A.; Toldam-Andersen, T. B.; Braun, P.

    2005-08-01

    Large-scale climate variability largely affects average climatic conditions and therefore is likely to influence the phenology of plants. In NW-Europe, the North Atlantic Oscillation (NAO) particularly influences winter climate and, through climate interactions on plants, flowering time of all tree species. In Denmark, like in many other NW-European countries, flowering of most tree species has become earlier since the end of the 1980’s. To quantify a possible relation between NAO and flowering time of tree species, two sources of phenological information from the Copenhagen area (Denmark) were analysed, i.e. pollen counts of the genus Betula and observed first bloom dates of Prunus avium. The Winter NAO explained 29 and 37% of the variation of monthly mean temperature for February and March, respectively. The influence of temperature on flowering time was up to 56% to 60% for the February April mean. A direct correlation of Winter NAO-index and flowering time also revealed a clear relation but the time of influence was earlier (December to February). This was shown to be the likely result of a combination of direct and time-lagged effects of the NAO on air and sea surface temperature. The NAO signal is apparently stored in the North Sea and then influences temperature east up to the Baltic States. It is shown that Denmark is right in the centre of direct and time-lagged effects of the NAO. This offers the possibility of using the NAO-index for predicting flowering time of Prunus avium. The beginning of pollen flow appears to be influenced too much by short-term perturbations of the climate system decreasing the value of the NAO-index for prediction. However, it indicates a close relationship between natural climate variability, measured by the NAO index, and flowering time of tree species for Denmark.

  5. Integrated Networks.

    ERIC Educational Resources Information Center

    Robinovitz, Stewart

    1987-01-01

    A strategy for integrated data and voice networks implemented at the University of Michigan is described. These networks often use multi-technologies, multi-vendors, and multi-transmission media that will be fused into a single integrated network. Transmission media include twisted-pair wire, coaxial cable, fiber optics, and microwave. (Author/MLW)

  6. Integrated Learning

    ERIC Educational Resources Information Center

    Gnanakan, Ken

    2012-01-01

    This book upholds the idea of learning and education as a means to individual development and social empowerment. It presents a holistic picture, looking at learning as an integral part of one's social and physical life. Strongly differing from existing classroom perspectives, the book analyses integrated learning at its broadest possible…

  7. Improving national surveillance of Lyme neuroborreliosis in Denmark through electronic reporting of specific antibody index testing from 2010 to 2012.

    PubMed

    Dessau, R B; Espenhain, L; Mølbak, K; Krause, T G; Voldstedlund, M

    2015-07-16

    Our aim was to evaluate the results of automated surveillance of Lyme neuroborreliosis (LNB) in Denmark using the national microbiology database (MiBa), and to describe the epidemiology of laboratory-confirmed LNB at a national level. MiBa-based surveillance includes electronic transfer of laboratory results, in contrast to the statutory surveillance based on manually processed notifications. Antibody index (AI) testing is the recommend laboratory test to support the diagnosis of LNB in Denmark. In the period from 2010 to 2012, 217 clinical cases of LNB were notified to the statutory surveillance system, while 533 cases were reported AI positive by the MiBa system. Thirty-five unconfirmed cases (29 AI-negative and 6 not tested) were notified, but not captured by MiBa. Using MiBa, the number of reported cases was increased almost 2.5 times. Furthermore, the reporting was timelier (median lag time: 6 vs 58 days). Average annual incidence of AI-confirmed LNB in Denmark was 3.2/100,000 population and incidences stratified by municipality ranged from none to above 10/100,000. This is the first study reporting nationwide incidence of LNB using objective laboratory criteria. Laboratory-based surveillance with electronic data-transfer was more accurate, complete and timely compared to the surveillance based on manually processed notifications. We propose using AI test results for LNB surveillance instead of clinical reporting.

  8. Integrative psychotherapy.

    PubMed

    Kozarić-Kovacić, Dragica

    2008-09-01

    The main purposes of the article are to present the history of integration in psychotherapy, the reasons of the development integrative approaches, and the approaches to integration in psychotherapy. Three approaches to integration in psychotherapy exist: theoretical integration, theoretical eclecticism, and common factors in different psychotherapeutic trends. In integrative psychotherapy, the basic epistemology, theory, and clinical practice are based on the phenomenology, field theory, holism, dialogue, and co-creation of dialogue in the therapeutic relationship. The main criticism is that integrative psychotherapy suffers from confusion and many unresolved controversies. It is difficult to theoretically and methodologically define the clinically applied model that is based on such a different epistemological and theoretical presumptions. Integrative psychotherapy is a synthesis of humanistic psychotherapy, object relations theory, and psychoanalytical self psychology. It focuses on the dynamics and potentials of human relationships, with a goal of changing the relations and understanding internal and external resistances. The process of integrative psychotherapy is primarily focused on the developmental-relational model and co-creation of psychotherapeutic relationship as a single interactive event, which is not unilateral, but rather a joint endeavor by both the therapist and the patient/client. The need for a relationship is an important human need and represents a process of attunement that occurs as a response to the need for a relationship, a unique interpersonal contact between two people. If this need is not met, it manifests with the different feelings and various defenses. To meet this need, we need to have another person with whom we can establish a sensitive, attuned relationship. Thus, the therapist becomes this person who tries to supplement what the person did not receive. Neuroscience can be a source of integration through different therapies. We

  9. Salmonella in pork cuttings in supermarkets and butchers' shops in Denmark in 2002 and 2006.

    PubMed

    Hansen, T B; Christensen, B B; Aabo, S

    2010-11-01

    The prevalence of Salmonella in fresh pork cuttings in Denmark in the years 2002 and 2006 was investigated at retail and compared with the retail supply pattern. A total of 1025 and 3473 samples were taken in 2002 from butcher's shops and supermarkets, respectively. The corresponding numbers in 2006 were 259 from butchers' shops and 628 from supermarkets. In 2002, 1.2% of all samples were positive for Salmonella; butchers' shops and supermarkets had 1.8% and 1.0% positive samples, respectively. The overall prevalence in 2006 was 4.2%, with prevalence of 8.1% and 2.6% for butchers' shops and supermarkets, respectively. Hence, increases around 3- to 5-fold were found. There was neither observed any parallel increase in Salmonella positive carcasses in Danish slaughterhouses during the study period, nor were any changes in supply routes towards slaughterhouses with higher prevalence observed, which could explain the apparent increase. We hypothesize that hygiene levels and ability to avoid cross-contamination and prevent growth of the organism, in the meat processing chain after slaughter were the most likely responsible factors. Results from this study indicate that the hygiene performance, particularly at retail, has a significant impact on the occurrence of Salmonella. This implies that there is no direct link between slaughterhouse Salmonella surveillance data and the level of Salmonella contamination at retail. To improve risk assessment of Salmonella in fresh pork meat, this study underlines the need for comprehensive retail data.

  10. How do I look? Body image perceptions among university students from England and Denmark.

    PubMed

    El Ansari, Walid; Clausen, Susanne Vodder; Mabhala, Andi; Stock, Christiane

    2010-02-01

    This study examined differences in body image perception between university students in two European countries, United Kingdom and Denmark. A total of 816 British and 548 Danish university students participated in a cross-sectional survey. A self-administered questionnaire assessed socio-demographic information, body image perception (as "too thin", "just right" or "too fat"), and the association of related factors with body image perception (nutrition behaviour, social support, perceived stressors and quality of life). The proportions of students who perceived themselves as "too thin", "just right", or "too fat" were 8.6%, 37.7%, and 53.7% respectively. Multi-factorial logistic regression analysis showed that students who perceived themselves as "too fat" were more likely to be from the British university, to be females, to be older than 30 years, to report stress due to their financial situation and were less likely to have a high quality of life. The findings highlight the need for interventions with focus on healthy food choices whilst acknowledging financial stressors and quality of life.

  11. Holistic assessment of a secondary water supply for a new development in Copenhagen, Denmark.

    PubMed

    Rygaard, M; Godskesen, B; Jørgensen, C; Hoffmann, B

    2014-11-01

    Increasing stress on water resources is driving urban water utilities to establish new concepts for water supply. This paper presents the consequences of proposed alternative water supply options using a unique combination of quantitative and qualitative methods from different research fields. A former industrial harbor area in Copenhagen, Denmark, is currently under development and all infrastructure will be updated to accommodate 40,000 inhabitants and 40,000 jobs in the future. To reduce stress on water resources it has been proposed to establish a secondary water supply in the area as an alternative to the conventional groundwater-based drinking water supply. Four alternative concepts for a secondary water supply have been considered: 1) slightly polluted groundwater for use in toilets and laundry, 2) desalinated brackish water for use in toilets, laundry, and dishwashers, 3) desalinated brackish water for all uses, including drinking water, and 4) local reclamation of rain and gray water for use in toilets and laundry. The concepts have been evaluated for their technical feasibility, economy, health risks, and public acceptance, while the concepts' environmental sustainability has been assessed using lifecycle assessment and freshwater use impact methods. The holistic assessment method exposes conflicting preference solutions depending on assessment criteria, and reveals multi-faceted consequences for choices in urban water management. Not one concept turns out unambiguously positive based on the evaluation criteria included here, but the systematic evaluation will leave decision-makers informed on the consequences of their choices.

  12. Laryngeal cancer in Denmark: a nationwide longitudinal study based on register linkage data.

    PubMed Central

    Guenel, P; Engholm, G; Lynge, E

    1990-01-01

    To identify high and low risk groups for laryngeal cancer in Denmark, all individuals aged 30-74 in the 1970 census were followed up over 10 years. Census data were linked with the Central Population Register to identify persons who died or emigrated during the follow up, and with the Danish Cancer Register to identify cases of laryngeal cancer. Individuals were categorised according to sex, age, and sociodemographic characteristics as declared on the census forms. A multivariate analysis was carried out by means of multiplicative Poisson models. The study showed that the risk of laryngeal cancer was strongly related to sociodemographic factors. The risk for skilled workers living in Copenhagen (relative risk (RR) 4.76, 95% confidence interval (CI) 3.61-6.28) was estimated to be almost five times higher than the risk for men self employed in agriculture and living in rural areas. The variation in the risk of laryngeal cancer is not fully explained by known variations in tobacco and alcohol consumption, and this study highlights additional risk factors particularly related to occupation and marital state. PMID:2383517

  13. Mobile phone use and the risk of skin cancer: a nationwide cohort study in Denmark.

    PubMed

    Poulsen, Aslak Harbo; Friis, Søren; Johansen, Christoffer; Jensen, Allan; Frei, Patrizia; Kjaear, Susanne Krüger; Dalton, Susanne Oksbjerg; Schüz, Joachim

    2013-07-15

    The International Agency for Research on Cancer has classified radiofrequency radiation as possibly carcinogenic. Previous studies have focused on intracranial tumors, although the skin receives much radiation. In a nationwide cohort study, 355,701 private mobile phone subscribers in Denmark from 1987 to 1995 were followed up through 2007. We calculated incidence rate ratios (IRRs) for melanoma, basal cell carcinoma, and squamous cell carcinoma by using Poisson regression models adjusted for age, calendar period, educational level, and income. Separate IRRs for head/neck tumors and torso/leg tumors were compared (IRR ratios) to further address potential confounders. We observed no overall increased risk for basal cell carcinoma, squamous cell carcinoma, or melanoma of the head and neck. After a follow-up period of at least 13 years, the IRRs for basal cell carcinoma and squamous cell carcinoma remained near unity. Among men, the IRR for melanoma of the head and neck was 1.20 (95% confidence interval: 0.65, 2.22) after a minimum 13-year follow-up, whereas the corresponding IRR for the torso and legs was 1.16 (95% confidence interval: 0.91, 1.47), yielding an IRR ratio of 1.04 (95% confidence interval: 0.54, 2.00). A similar risk pattern was seen among women, though it was based on smaller numbers. In this large, population-based cohort study, little evidence of an increased skin cancer risk was observed among mobile phone users.

  14. Benzene exposure and the effect of traffic pollution in Copenhagen, Denmark

    NASA Astrophysics Data System (ADS)

    Skov, Henrik; Hansen, Asger B.; Lorenzen, Gitte; Andersen, Helle Vibeke; Løfstrøm, Per; Christensen, Carsten S.

    Benzene is a carcinogenic compound, which is emitted from petrol-fuelled cars and thus is found ubiquitous in all cities. As part of the project Monitoring of Atmospheric Concentrations of Benzene in European Towns and Homes (MACBETH) six campaigns were carried out in the Municipality of Copenhagen, Denmark. The campaigns were distributed over 1 year. In each campaign, the personal exposure to benzene of 50 volunteers (non-smokers living in non-smoking families) living and working in Copenhagen was measured. Simultaneously, benzene was measured in their homes and in an urban network distributed over the municipality. The Radiello diffusive sampler was applied to sample 5 days averages of benzene and other hydrocarbons. Comparison of the results with those from a BTX-monitor showed excellent agreement. The exposure and the concentrations in homes and in the urban area were found to be close to log-normal distribution. The annual averages of the geometrical mean values were 5.22, 4.30 and 2.90 μg m -3 for personal exposure, home concentrations and urban concentrations, respectively. Two main parameters are controlling the general level of benzene in Copenhagen: firstly, the emission from traffic and secondly, dispersion due to wind speed. The general level of exposure to benzene and home concentrations of benzene were strongly correlated with the outdoor level of benzene, which indicated that traffic is an important source for indoor concentrations of benzene and for the exposure to benzene.

  15. Cluster of Legionnaires disease in a newly built block of flats, Denmark, December 2008 - January 2009.

    PubMed

    Krøjgaard, L H; Krogfelt, K A; Albrechtsen, H J; Uldum, S A

    2011-01-06

    During December 2008 to January 2009, two persons contracted Legionnaires’ disease in a newly built block of flats in a suburb of Copenhagen in Denmark. Polymerase chain reaction and culture was used to diagnose Legionnaires’ disease in this cluster. Isolates from both patients tested positive for Legionella pneumophila serogroup 1 subgroup Philadelphia sequence type 1 and the same strain was detected in hot water samples taken from the residential area indicating that the hot water supply system was the most likely source of infection. Legionella was not detected in the cold water. Two interventions were conducted to limit the Legionella colonisation of the piping and storage tanks and the effect was monitored by investigating water samples from various sites in the block of flats. Only the second intervention had a sufficient effect on the Legionella colonisation. The cluster described here points to several risk factors regarding growth of Legionella in hot water systems: (i) stagnancy of water from when the building is constructed and piping installed and until residents move in, (ii) stagnancy and low temperature (from room temperature to approximately 38°C) of water in shower hoses and (iii) failure in operation of and control measures for the hot water system.

  16. Medicine, natural philosophy, and the influence of Melanchthon in reformation Denmark and Norway.

    PubMed

    Fink-Jensen, Morten

    2006-01-01

    In the sixteenth and early seventeenth centuries, all intellectual pursuits in Europe were colored by the religious conditions of the age. Accordingly, investigations into nature were unable to avoid issues dealing with the workings of divine power. The reestablishment of the University of Copenhagen after the Reformation of 1536 in the joint kingdom of Denmark and Norway prompted the formulation of an official Lutheran program for the study of medicine and natural philosophy (including anatomy). This program was wholly based on the ideas of the German reformer Philip Melanchthon, the aim being to apply knowledge of, for example, anatomy in support of the newly reformed Lutheran society. Thus, the crown and the church officially sanctioned Melanchthon's thoughts on natural philosophy as a means to apprehend, first, the majestic glory of divine providence; second, that man was truly created and assigned his place by God; and third, that it was demanded of all men and women that they submit themselves to the will of God and the laws of the public authorities.

  17. Predicting phosphorus losses with the PLEASE model on a local scale in Denmark and the Netherlands.

    PubMed

    van der Salm, Caroline; Dupas, Remi; Grant, Ruth; Heckrath, Goswin; lversen, Bo V; Kronvang, Brian; Levi, Clémentine; Rubaek, Gitte; Schoumans, Oscar F

    2011-01-01

    To reduce losses from agricultural soils to surface water, mitigation options have to be implemented as a local scale. For a cost-effective implementation of these measures, an instrument to identify critical areas for P leaching is indispensable. In many countries, P-index methods are used to identify areas as risk for P losses to surface water. In flat areas, where losses by leaching are dominant, these methods have their limitations because leaching is often not described in detail, PLEASE, is a simple mechanistic model designed to stimulate P Losses by leaching at the field scale using a limited amount of local field data. In this study, PLEASE, was applied to 17 lowland sites in Denmark and 14 lowland sites in the Netherlands. Results show that the simple model simulated measured fluxes and concentrations in water from pipe drains, suction cups, and groundwater quite well. The modeling efficiency ranged from 0.92 for modeling total-P fluxes to 0.36 fr modeling concentrations in groundwater. Poor results were obtained for heavy clay soils and eutrophic peat soils, where fluxes and concentration were strongly underestimated by the model. The poot performance for the heavy clay soil can be explained by the transport of P through macropores to the drain pipes and the underestimation of overland flow on this heavy-textured soil. In the eutrophic peat soils, fluxes were underestimated due to the release of P from deep soil layers.

  18. Utilization of dental health services among middle-aged people in Sweden and Denmark.

    PubMed

    Kronström, Mats; Palmqvist, Sigvard; Söderfeldt, Björn; Vigild, Merete

    2002-10-01

    In 1999, questionnaires were sent to random samples of 1001 Swedish citizens aged 55-79 years and 1175 Danish citizens aged 45-69 years. Various questions were asked concerning dental conditions, dental visit frequency per year, and money spent annually on dental care, etc. The objectives were to assess differences in the utilization of dental services and to compare out-of-pocket costs for dental care in Sweden and Denmark with control for age, gender, dental conditions and income. More than 80% of the subjects reported that a dentist had examined them less than 1 year previously. However, 77% of the Danes reported dental visits twice a year or more compared to 28% of the Swedes. Although the Danes reported a more frequent use of dental services, they had poorer dental conditions compared to the Swedes. Even though the Swedes used dental services less often than the Danes did, more subjects reported high 12-month out-of-pocket costs. In the present study, separate models were constructed for the two countries because there could be different mechanisms at play, as indicated by the results. The different insurance systems along with different degrees of commercialization in the two countries might be the most decisive factors in this context.

  19. Health care cost containment in Denmark and Norway: a question of relative professional status?

    PubMed

    Andersen, Lotte B

    2014-04-01

    The demand for publicly subsidized health care services is insatiable, but the costs can be contained in different ways: formal rules can limit access to and the number of subsidized services, demand and supply can be regulated through the price mechanism, the relevant profession can contain the costs through state-sanctioned self-regulation, and other professions can contain the costs (e.g. through referrals). The use of these cost containment measures varies between countries, depending on demand and supply factors, but the relative professional status of the health professions may help explain why different countries use cost containment measures differently for different services. This article compares cost containment measures in Denmark and Norway because these countries vary with regard to the professional status of the medical profession relative to other health care providers, while other relevant variables are approximately similar. The investigation is based on formal agreements and rules, historical documents, existing analyses and an analysis of 360 newspaper articles. It shows that high relative professional status seems to help professions to avoid user fees, steer clear of regulation from other professions and regulate the services produced by others. This implies that relative professional status should be taken into consideration in analyses of health care cost containment.

  20. Risk factors associated with interdog aggression and shooting phobias among purebred dogs in Denmark.

    PubMed

    Rugbjerg, Helene; Proschowsky, Helle Friis; Ersbøll, Annette Kjaer; Lund, Jørgen Damkjaer

    2003-04-30

    The prevalence of behaviour problems is reported from a questionnaire study among members of the Danish Kennel Club (DKC). In total, 4359 dog owners were included in the analyses. With logistic regression, we analysed four behaviour problems: dominance towards the owner, interdog dominance aggression, separation anxiety and shooting phobia. Compared to Labrador Retrievers, the following breeds and breed groups had higher odds of being reported to have interdog dominance aggression: Belgian Sheepdogs, Dachshunds, Dalmatians, German Shepherds, Hovawarts, Pinschers, Rottweilers, Scent dogs and Spitz dogs. Poodles, retrieving/flushing dogs, Sheepdogs, Spitz dogs and terriers had higher odds of shooting phobia. The odds of interdog dominance aggression were higher among dogs owned by younger dog owners compared to dogs owned by older dog owners. Dogs living in the capital area of Copenhagen had increased odds of interdog dominance aggression as compared to dogs living in other parts of Denmark. Dogs belonging to owners with limited knowledge of the breed before acquiring the dog had higher odds of interdog dominance aggression. Dogs attending obedience training classes had reduced odds of shooting phobia. Dogs belonging to dog breeders had reduced odds of being reported to have the investigated behaviour problems.

  1. Faunistic review of the cuckoo wasps of Fennoscandia, Denmark and the Baltic countries (Hymenoptera: Chrysididae).

    PubMed

    Paukkunen, Juho; Rosa, Paolo; Soon, Villu; Johansson, Niklas; Ødegaard, Frode

    2014-09-19

    A critical and annotated review of published records of the Chrysididae of the Nordic and Baltic countries and the Russian part of Fennoscandia is presented with some taxonomic and faunistic notes. A total of 73 species are listed from the region. Additionally, 17 species are deleted. Three species are recorded for the first time from Denmark, six species from Estonia, one from Finland, eleven from Latvia, four from Norway, one from Sweden and 15 from Russian Fennoscandia. Elampus foveatus and Chrysis pulcherrima are reported for the first time from the Nordic and Baltic countries. Lectotypes are designated for Hedychrum cupreum Dahlbom, 1845, Chrysis zetterstedti Dahlbom, 1845, Chrysis succincta var. chrysoprasina Trautmann, 1927, Chrysis succincta var. virideocincta Trautmann, 1927 and Chrysis succincta var. nordstromi Trautmann, 1927. Information and images of the holotypes of Hedychrum metallicum Dahlbom, 1854, Chrysis var. westerlundi Trautmann, 1927 are given. Chrysis integra Dahlbom, 1829 is found to be a new synonym of Hedychridium ardens (Coquebert, 1801) and Chrysis scintillans Valkeila, 1971 a new synonym of Chrysis solida Haupt, 1957. Chrysis terminata Dahlbom, 1854 is reported for the first time as the valid name for C. ignita Form A sensu Linsenmaier, 1959.

  2. Environmental risk assessment of human pharmaceuticals in Denmark after normal therapeutic use.

    PubMed

    Stuer-Lauridsen, F; Birkved, M; Hansen, L P; Lützhøft, H C; Halling-Sørensen, B

    2000-04-01

    An environmental risk assessment is presented for the 25 most used pharmaceuticals in the primary health sector in Denmark. Predicted environmental concentrations (PECs) for the aquatic environment were calculated using conservative assumptions and all PECs exceeded 1 ng/l. Measured concentrations were in general within a factor of 2-5 of PECs and ranged from approximately 0.5 ng/l to 3 micrograms/l for nine of the pharmaceuticals reported in literature. The calculation of predicted no-effect concentration (PNEC) based on aquatic ecotoxicity data was possible for six of the pharmaceuticals. PEC/PNEC ratio exceeded one for ibuprofen, acetylsalicylic acid, and paracetamol. For estrogens the PEC/PNEC ratio approached one when non-standard test was used. The ratio was below one for estrogens (standard test), diazepam and digoxin. For the terrestrial compartment, toxicity data were not available, and no assessment was carried out. Comparisons of predicted concentrations of furosemide, ibuprofen, oxytetracycline and ciprofloxacin in sludge based on either preliminary experimental sludge-water partition coefficients (Kd), octanol-water coefficients (Kow) or acid-base constants (pKa) revealed large variations.

  3. Extent and variations in mobile phone use among drivers of heavy vehicles in Denmark.

    PubMed

    Troglauer, Thomas; Hels, Tove; Christens, Peter Falck

    2006-01-01

    A substantial body of research has shown that use of mobile phones while driving can impair driving performance and increase the risk of being involved in accidents. Similarly, mobile phone use seems to be an increasing activity thus representing a relevant traffic safety issue. This paper investigates the extent and variations in mobile phone use among drivers of heavy vehicles in Denmark. The data was collected through written questionnaires and had a response rate of 58%. It was found that more than 99% of the drivers used mobile phones while driving. Despite a prohibition of hand-held mobile phone use while driving 31% of the drivers reported to do so. Analysis of the variations in usage found a positive significant relationship between driving hours and phone use. A negative linear effect was found between age and phone use. Similarly, a positive significant association was found between the number of stops and the amount of phone use. 0.5% reported that their use of mobile phones had contributed to an accident, while 6% had experienced their mobile phone use causing a dangerous situation. However, 66% reported experiencing dangerous situations because of others road users' mobile phone use. Various implications of the findings are discussed particularly in relation to the drivers with high exposure.

  4. Quality-Shaping Factors and Endodontic Treatment amongst General Dental Practitioners with a Focus on Denmark

    PubMed Central

    Demant, Sune; Markvart, Merete; Bjørndal, Lars

    2012-01-01

    There is a gap between the endodontic outcome that can be achieved and the outcome observed on the basis of worldwide general dental practitioner data. The quality of root canal treatment (RCT) is shaped by the dentist's knowledge, attitude, and skills, but it may also be influenced by the patient's demands and degree of satisfaction. The topic has only been sparsely investigated. Although dental health has increased over the years in Denmark, the number of performed root fillings has also increased, probably because the number of tooth extractions have declined and more molar teeth have been treated. Caries appears to be the main cause for performing RCT and a preventive approach by employing stepwise excavation may reduce RCT, but this strategy does not remove the gap. Factors influencing RCT quality could be the status on adoption of nickel-titanium rotary technology, more focus on infection control (rubber dam use, knowledge of factors important for prognosis), as dentists often think that they are good at doing RCT, but often perform inadequately, an alteration of clinician's awareness of their performance in the context of dental practices, seems warranted. Finally, the development of new preventive modalities for pulp and apical inflammation are crucial. PMID:22536241

  5. Molecular characterization of melanoma cases in Denmark suspected of genetic predisposition.

    PubMed

    Wadt, Karin A W; Aoude, Lauren G; Krogh, Lotte; Sunde, Lone; Bojesen, Anders; Grønskov, Karen; Wartacz, Nine; Ek, Jakob; Tolstrup-Andersen, Morten; Klarskov-Andersen, Mette; Borg, Åke; Heegaard, Steffen; Kiilgaard, Jens F; Hansen, Thomas V O; Klein, Kerenaftali; Jönsson, Göran; Drzewiecki, Krzysztof T; Dunø, Morten; Hayward, Nicholas K; Gerdes, Anne-Marie

    2015-01-01

    Both environmental and host factors influence risk of cutaneous melanoma (CM), and worldwide, the incidence varies depending on constitutional determinants of skin type and pigmentation, latitude, and patterns of sun exposure. We performed genetic analysis of CDKN2A, CDK4, BAP1, MC1R, and MITFp.E318K in Danish high-risk melanoma cases and found CDKN2A germline mutations in 11.3% of CM families with three or more affected individuals, including four previously undescribed mutations. Rare mutations were also seen in CDK4 and BAP1, while MC1R variants were common, occurring at more than twice the frequency compared to Danish controls. The MITF p.E318K variant similarly occurred at an approximately three-fold higher frequency in melanoma cases than controls. To conclude, we propose that mutation screening of CDKN2A and CDK4 in Denmark should predominantly be performed in families with at least 3 cases of CM. In addition, we recommend that testing of BAP1 should not be conducted routinely in CM families but should be reserved for families with CM and uveal melanoma, or mesothelioma.

  6. Postgraduate education on electro-active polymers at Southern Denmark University

    NASA Astrophysics Data System (ADS)

    Jones, Richard W.

    2009-03-01

    A recently introduced elective to the Master's of Science in Mechatronics program at Southern Denmark University, entitled 'Mechatronics: Design and Build' concentrates on some of the interdisciplinary aspects of Mechatronics Engineering. The 'Motion Control of Mechatronic Devices' is the main theme of this elective. Within this 'theme' the modelling, identification and compensation of nonlinear effects such as friction, stiction and hysteresis are considered. One of the most important components of the elective considers 'Smart Materials' and their use for actuation purposes. The theory, modelling and properties of piezoceramics. magneto- and electro- rheological fluids and dielectric electro active polymers (DEAP) are introduced in the 'Smart Materials' component. This paper initially reviews the laboratory experiments that have been developed for the dielectric electro active polymer section of the 'Mechatronics: Design and Build' elective. In lectures the students are introduced to the basic theory and fabrication of tubular actuators, that use DEAP material based on smart compliant electrode technology. In the laboratory the students to (a) carry out a series of experiments to characterise the tubular actuators, and (b) design a closed-loop position controller and test the performance of the controlled actuator for both step changes in desired position and periodic input reference signals. The last part of this contribution reviews some of the DEAP-based demonstration devices that been developed by Danfoss PolyPower A/S using their PolyPowerTM material which utilizes smart compliant electrode technology.

  7. Ichnology of pelagic carbonate in New Zealand and Denmark: Shelf Sea or Deep Sea

    SciTech Connect

    Ekdale, A.A. )

    1990-05-01

    Today, pelagic carbonate ooze is an exclusive feature of deep-sea environments 1 km or more in depth. In contrast, the extensive epicratonic seas that characterized the Late Cretaceous and early Tertiary received great thicknesses of pelagic carbonate sediment in environments only a few hundred meters deep. Distinguishing between deep-sea and shelf-sea carbonate is not an easy task, but ichnologic investigation helps. Biogenic sedimentary structures, ichnofacies, and ichnofabrics in Cretaceous-Tertiary epicratonic pelagic deposits display many similarities to those in deep-sea sediment. Ichnologic features in shelf-sea chalk and limestone in both New Zealand and northern Europe reveal some interesting paleobathymetric trends. These trends include a general decrease in crustacean traces (Thalassinoides, etc.) and bioerosion traces (Trypanites, etc.) with increasing water depth, accompanied by a concomitant increase in worm burrows (Zoophycos, etc.). Maastrichtian-Oligocene pelaic limestone in New Zealand and Maastrichtian-Paleocene chalk in Denmark neither of which represent a truly deep-sea setting, exhibit similar ichnofacies and ichnofabrics. Some notable differences exist because the New Zealand platform was less extensive and more tectonically active than the northern European shelf. Pelagic strata in New Zealand are associated with shallow-water quartzose sandstone beneath and fossiliferous calcarenite above, as well as deep-water bedded chert within, the pelagic carbonate sequence. In New Zealand strata Zoophycos-rich facies dominate Thalassinoides-rich facies, and bored hardgrounds are uncommon; in Danish chalk sequences the opposite is true in both cases.

  8. Toxicity of organic chemical pollution in groundwater downgradient of a landfill (Grindsted, Denmark)

    SciTech Connect

    Baun, A.; Jensen, S.D.; Bjerg, P.L.; Christensen, T.H.; Nyholm, N.

    2000-05-01

    The aim of the present study was to describe the occurrence and distribution of toxicity related to organic chemical contaminants in the leachate plume downgradient of the Grindsted Landfill (Denmark). A total of 27 groundwater samples were preconcentrated by solid-phase extraction (SPE) using XAD-2 as the resin material. This treatment effectively eliminated sample matrix toxicity caused by inorganic salts and natural organic compounds and produced an aqueous concentrate of the nonvolatile chemical contaminants. The SPE extracts were tested in a battery of standardized short-term aquatic toxicity tests with luminescent bacteria (Vibrio fischeri), algae (Selenastrum capricornutum), and crustaceans (Daphnia magna). Additional genotoxicity tests were made using the umuC test (Salmonella typhimurium). Biotests with algae and luminescent bacteria were the most sensitive tests. On the basis of results with these two bioassays, it was concluded that SPE extracts of groundwater collected close to the landfill were toxic. The toxicity decreased with the distance from the landfill. At distances greater than 80 m from the border of the landfill, the groundwater toxicity was not significantly different from the background toxicity. SPE extracts were not toxic to Daphnia, and no genotoxicity was observed in the umuC test. The overall findings indicate that a battery of biotests applied on preconcentrated groundwater samples can be a useful tool for toxicity characterization and hazard ranking of groundwater polluted with complex chemical mixtures, such as landfill leachates.

  9. The prevalence and clinical significance of intestinal parasites in HIV-infected patients in Denmark.

    PubMed

    Stensvold, Christen Rune; Nielsen, Susanne Dam; Badsberg, Jens-Henrik; Engberg, Jørgen; Friis-Møller, Nina; Nielsen, Sanne Søgaard; Nielsen, Henrik Vedel; Friis-Møller, Alice

    2011-02-01

    To investigate the prevalence and clinical significance of intestinal parasites in human immunodeficiency virus (HIV)-infected patients, faecal specimens from 96 HIV-infected patients were submitted to microbiological analyses, including microscopy and polymerase chain reaction for protozoa and enteropathogenic bacteria. Results of microbiological analyses were compared with self-reported gastrointestinal complaints collected using a validated questionnaire. Thirty-two (33%) patients were positive for parasites. However, opportunistic parasites (Isospora and Cryptosporidium) were detected in only 2 instances. Entamoeba dispar was detected in 10 cases, 9 of which represented men who have sex with men (MSM). Despite generally low HIV RNA loads and high CD4+ T-cell counts, 42% of the 76 patients reporting symptoms complained of diarrhoea, 31% of whom were parasite-positive. The presence of diarrhoea was not associated with the presence or absence of parasites; neither was it associated with receiving highly active anti-retroviral therapy (HAART) in general, or protease inhibitors (PI) in particular. A CD4+ T-cell count <200 cells/mm³ was not associated with parasitic infection or with diarrhoea. The data show that diarrhoea is a common symptom among HIV-infected patients in Denmark, but do not indicate that the diarrhoea is due to intestinal parasites.

  10. Phylogenetic and epidemiological analysis of measles outbreaks in Denmark, 2013 to 2014.

    PubMed

    Rasmussen, Lasse Dam; Fonager, Jannik; Knudsen, Lisbet Krause; Andersen, Peter Henrik Senten; Rønn, Jesper; Poulsen, Mille Weismann; Franck, Kristina Træholt; Fischer, Thea Kølsen

    2015-01-01

    Despite the introduction of safe, effective vaccines decades ago and joint global public health efforts to eliminate measles, this vaccine-preventable disease continues to pose threats to children's health worldwide. During 2013 and 2014, measles virus was introduced into Denmark through several independent importations. This resulted in a number of secondary cases (n=7), with two clusters in 2013 and one in 2014. In total, there were 44 cases of measles. Most cases (n=41) were laboratory confirmed by detection of measles virus genome by real-time reverse transcription (RT)-PCR and IgM antibodies. The viruses from confirmed cases were genotyped by sequencing. Only one genotype circulated each year, i.e. D8 and B3, respectively. Sequencing of measles virus from different clinical specimens from the same patients revealed that sequence variants of measles viruses might co-exist and co-transmit during an outbreak. The majority of the cases were unvaccinated (n=27) or recipients of one dose of measles-mumps-rubella (MMR) vaccine (n=7). In addition, two fully vaccinated adult cases were reported in 2014. We demonstrate the transmission of measles virus in a population in which the two-dose MMR vaccination coverage rate was 80% and how even vaccinated individuals may be at risk of contracting measles once transmission has been established.

  11. Translation and Adaptation of the Genetic Counselling Outcome Scale (GCOS-24) for Use in Denmark.

    PubMed

    Diness, Birgitte Rode; Overbeck, Gritt; Hjortshøj, Tina Duelund; Hammer, Trine Bjørg; Timshel, Susanne; Sørensen, Else; McAllister, Marion

    2017-03-06

    Outcome measurement in clinical genetics is challenging. Robust outcome measures are needed to provide evidence to support service development within genetic counseling. The Genetic Counselling Outcome Scale (GCOS-24), a Patient Reported Outcome Measure (PROM), was developed in English and validated with clinical genetics patients in the British NHS. This study reports the translation and adaptation of the GCOS-24 for use in Denmark. GCOS-24 was translated and back translated, supervised by an expert committee. Feedback on the first version was collected from genetic counseling patients in qualitative interviews focusing on instructions for use, response options and specific items considered semantically difficult. After further adjustment the adapted and translated version was administered to a second sample of patients, with responses analyzed using descriptive statistics. Eighteen interviews were conducted, and led to adjustment of item wording. Sixty-one patients completed the final version GCOS-24dk. Internal consistency is good (Cronbach's α =0.79), with an acceptable number of missing responses and no floor or ceiling effect observed. GCOS-24 has been successfully translated and adapted for use in a Danish setting. The study confirms the feasibility of local adaptation of patient reported outcome measures and stresses the importance of adaptation, even across quite similar populations and health care systems.

  12. Environmental assessment of garden waste management in the Municipality of Aarhus, Denmark

    SciTech Connect

    Boldrin, Alessio; Andersen, Jacob K.; Christensen, Thomas H.

    2011-07-15

    An environmental assessment of six scenarios for handling of garden waste in the Municipality of Aarhus (Denmark) was performed from a life cycle perspective by means of the LCA-model EASEWASTE. In the first (baseline) scenario, the current garden waste management system based on windrow composting was assessed, while in the other five scenarios alternative solutions including incineration and home composting of fractions of the garden waste were evaluated. The environmental profile (normalised to Person Equivalent, PE) of the current garden waste management in Aarhus is in the order of -6 to 8 mPE Mg{sup -1} ww for the non-toxic categories and up to 100 mPE Mg{sup -1} ww for the toxic categories. The potential impacts on non-toxic categories are much smaller than what is found for other fractions of municipal solid waste. Incineration (up to 35% of the garden waste) and home composting (up to 18% of the garden waste) seem from an environmental point of view suitable for diverting waste away from the composting facility in order to increase its capacity. In particular the incineration of woody parts of the garden waste improved the environmental profile of the garden waste management significantly.

  13. Preventive home visits to older people in Denmark--why, how, by whom, and when?

    PubMed

    Vass, M; Avlund, K; Hendriksen, C; Philipson, L; Riis, P

    2007-08-01

    In Denmark, political decisions improved the implementation of 'preventative thinking' into every-day clinical work. The potential benefits of preventive efforts have been supported by legislative and administrative incentives, and an ongoing effort to remain focused on the benefits of these initiatives towards older people is politically formulated and underlined as part of the new structured municipality reform. Evidence of beneficial effects of health promotion and prevention of disease in old age is well documented. In-home visits with individualised assessments make it possible to reach older persons not normally seen in the health care system. In-home assessment is not just a health check, but also an opportunity to meet individual needs that may be of importance for older people to stay independent. Preventive home visits may be part of an overall culture and strategy to avoid or prevent functional decline. There is an urgent need of an interdisciplinary teamwork and management for such programmes, incorporating flexible cooperation between the primary and secondary health care sector. The value and importance of geriatric and gerontological education is evidence based.

  14. Resistance differences between chlorpyrifos and synthetic pyrethroids in Cimex lectularius population from Denmark.

    PubMed

    Kilpinen, Ole; Kristensen, Michael; Jensen, Karl-Martin Vagn

    2011-11-01

    Bed bug, Cimex lectularius L., populations were investigated for resistance against permethrin and chlorpyrifos in a topical application bioassay, after an initial establishment of a discriminating dose with a susceptible population. For both insecticides, ca. two times the lethal dose LD(99) was selected: 2,560 ng of permethrin and 200 ng of chlorpyrifos per bed bug, respectively. Bed bugs were collected from infested homes in Denmark at ten locations and bred in the laboratory. The frequency of permethrin-resistant individuals was high in Danish bed bug populations as susceptible individuals were only found in three of ten populations. In contrast, the frequency of chlorpyrifos-resistant individuals was low in Danish bed bug populations, but resistant individuals were found in five of ten populations. To test the significance of the observed resistance, we performed tarsal contact test with commercially available insecticides. The test indicated that both a permethrin and a deltamethrin product had very low efficacy against the field-collected bed bug populations. Despite the reduced sensitivity to synthetic pyrethroids, all populations tested in the tarsal test on the commercial product with micro-encapsulated chlorpyrifos resulted in close to 100% mortality.

  15. Pesticides in water supply wells in Zealand, Denmark: a statistical analysis.

    PubMed

    Malaguerra, Flavio; Albrechtsen, Hans-Jørgen; Thorling, Lærke; Binning, Philip John

    2012-01-01

    Data from the Danish National Borehole Database are used to predict drinking water well vulnerability to contamination by pesticides, and to identify the dominant mechanisms leading to well pollution in Zealand, Denmark. The frequency of detection and concentrations of 4 herbicides and 3 herbicide metabolites are related to factors accounting for geology (thicknesses of sand, clay and chalk layers), geographical location (distance to surface water and distance to contaminated sites), redox conditions and well depth using logistic regression, the binomial test and Spearman correlation techniques. Results show that drinking water wells located in urban areas are more vulnerable to BAM and phenoxy acids contamination, while non-urban area wells are more subject to bentazone contamination. Parameters accounting for the hydraulic connection between the well and the surface (well depth and thickness of the clay confining layer) are often strongly related to well vulnerability. Results also show that wells close to surface water are more vulnerable to contamination, and that sandy layers provide better protection against the leaching of oxidizable pesticides than clay aquitards, because they are more likely to be aerobic. 4-CPP is observed more often at greater well depth, perhaps because of anaerobic dechlorination of dichlorprop. The field data are used to create a set of probabilistic models to predict well vulnerability to contamination by pesticides.

  16. Stroke in parents who lost a child: a nationwide follow-up study in Denmark.

    PubMed

    Li, Jiong; Johnsen, Søren P; Olsen, Jørn

    2003-01-01

    The association between psychological stress and stroke remains uncertain. We therefore examined whether or not one of the most extreme psychological stressors, the death of a child, was associated with the risk of stroke in a nationwide population-based follow-up study. All 21,062 parents who lost a child in Denmark during 1980-1996 were compared with 293,745 parents who had not lost a child. The overall adjusted relative risk (RR) of stroke was 1.00 (95% CI = 0.83-1.20) among the exposed after up to 18 years of follow-up. The RRs for fatal stroke and nonfatal stroke were 0.69 (95% CI = 0.37-1.26) and 1.03 (95% CI = 0.85-1.24), respectively. The RRs for hemorrhagic and nonhemorrhagic stroke were 1.02 (95% CI = 0.77-1.36) and 0.94 (95% CI = 0.74-1.20), respectively. The risk of stroke did not differ irrespective of whether the death of the child was unexpected or not. The death of a child was not associated with any substantially increased risk of stroke in the bereaved parents.

  17. 'Struensee's memoir on the situation of the King' (1772): Christian VII of Denmark.

    PubMed

    Schioldann, Johan

    2013-06-01

    Christian VII of Denmark (1749-1808) was insane throughout his long reign. The royal physician, Johann Friedrich Struensée (1737-72), usurped his power. In 1771 the King appointed him Privy Cabinet Minister. Struensée revolutionized the whole administration of the Danish-Norwegian kingdom and had an adulterous relationship with the Queen, Caroline Mathilda, George III's sister. In January 1772 he was arrested, sentenced to death for lese-majesty and executed. During his confinement, he wrote a memoir on the King's condition, which he considered to be caused by, or the effect of, masturbation. In 1906 Christiansen interpreted it as a case of dementia praecox, i.e. schizophrenia. It is now suggested that Christian's insanity, like that of George III (his cousin), might have been due to porphyria - the 'royal malady', possibly inherited through his mother, Princess Louise of England or his father, King Frederik V, who died from an illness which retrospectively resembles a case of porphyria.

  18. Marketization of refuse collection in Denmark: social and environmental quality jeopardized.

    PubMed

    Busck, Ole

    2007-08-01

    Refuse collection has been the main public service to be outsourced in Denmark since the E.U. guidelines on public procurement came into force in 1993. The contracting activities of the municipalities are framed by a complex set of ideologies and objectives, in addition to regulations. At both EU level and at national level, the demands for marketization of the public sector are counterbalanced by demands for social and environmental considerations. The procurement directive reflects the balance legalizing the inclusion of such requirements by contracting. The Danish experiences, however, tell a grim tale of subordination of social requirements in municipal contracting practices with implications for the quality of the service. The results of a recent study of developments in the working conditions at commercial collection companies show deterioration in respect of health and safety, competence building and job security concurrent with the increase in outsourcing and competition in the sector. In the analysis of the results, a combination of municipal cost-saving strategies, harsh market forces and cultural influences are identified as causal factors. Drawing on a brief institutional analysis, it is concluded that the existing normative and regulative framework of municipal contracting needs reinforcement if societal intentions of qualified public services and acceptable working conditions are to be effective. Initiatives to simultaneously improve working conditions and environmental results of collection are called for.

  19. Analyzing the relationship between car generation and severity of motor-vehicle crashes in Denmark.

    PubMed

    Rich, Jeppe; Prato, Carlo Giacomo; Hels, Tove; Lyckegaard, Allan; Kristensen, Niels Buus

    2013-05-01

    While the number of fatalities on Danish roads has decreased in the last 40 years, research has not investigated the contribution of legislation changes, enforcement measures, technological enhancements, infrastructural improvements and human factors to this reduction. In the context of a Danish car market with remarkably high registration tax that causes potential buyers to hold longer onto old cars, the relationship between technological enhancements of vehicles and severity of crashes requires particular attention. The current study investigated the relationship between car generation (i.e., car's first registration year) and injury severity sustained by car drivers involved in accidents in Denmark between 2004 and 2010. A generalized ordered logit model was estimated while controlling for several characteristics of the crash, the vehicle and the persons involved, and a sensitivity analysis was performed to assess the effect of car generation on drivers' injury severity. Results illustrate that newer car generations are associated to significantly lower probability of injury and fatality, and that replacing older cars with newer ones introduces significant and not to be overlooked benefits for both population and society.

  20. Does educational status impact adult mortality in Denmark? A twin approach.

    PubMed

    Madsen, Mia; Andersen, Anne-Marie Nybo; Christensen, Kaare; Andersen, Per Kragh; Osler, Merete

    2010-07-15

    To disentangle an independent effect of educational status on mortality risk from direct and indirect selection mechanisms, the authors used a discordant twin pair design, which allowed them to isolate the effect of education by means of adjustment for genetic and environmental confounding per design. The study is based on data from the Danish Twin Registry and Statistics Denmark. Using Cox regression, they estimated hazard ratios for mortality according to the highest attained education among 5,260 monozygotic and 11,088 dizygotic same-sex twin pairs born during 1921-1950 and followed during 1980-2008. Both standard cohort and intrapair analyses were conducted separately for zygosity, gender, and birth cohort. Educational differences in mortality were demonstrated in the standard cohort analyses but attenuated in the intrapair analyses in all subgroups but men born during 1921-1935, and no effect modification by zygosity was observed. Hence, the results are most compatible with an effect of early family environment in explaining the educational inequality in mortality. However, large educational differences were still reflected in mortality risk differences within twin pairs, thus supporting some degree of independent effect of education. In addition, the effect of education may be more pronounced in older cohorts of Danish men.

  1. Adult education and the challenges of regional development: Policy and sustainability in North Denmark

    NASA Astrophysics Data System (ADS)

    Rasmussen, Palle; Staugaard, Hans Jørgen

    2016-10-01

    Adult education is governed at many levels - internationally, nationally and locally. The authors of this paper look at the challenges, structures and practices of adult education policy at the local level, more specifically in North Denmark (Northern Jutland), one of the five administrative regions of the Danish nation-state. In many ways, the current educational challenges in this remote region of Europe are similar to what can be observed worldwide and especially in countries which are generally considered welfare states. The authors see the growing social and educational divide between the region's peripheral areas and its largest city centre as a major challenge - for society as a whole and for adult education in particular. It is from this perspective that the authors describe the present structures of adult education in the region and the strategies employed by local authorities and educational institutions. This is followed by an evaluation of both structures and efforts in terms of their ability to cope with the challenges.

  2. Integrated diagnostics

    NASA Technical Reports Server (NTRS)

    Hunthausen, Roger J.

    1988-01-01

    Recently completed projects in which advanced diagnostic concepts were explored and/or demonstrated are summarized. The projects begin with the design of integrated diagnostics for the Army's new gas turbine engines, and advance to the application of integrated diagnostics to other aircraft subsystems. Finally, a recent project is discussed which ties together subsystem fault monitoring and diagnostics with a more complete picture of flight domain knowledge.

  3. Feedback Integrators

    NASA Astrophysics Data System (ADS)

    Chang, Dong Eui; Jiménez, Fernando; Perlmutter, Matthew

    2016-12-01

    A new method is proposed to numerically integrate a dynamical system on a manifold such that the trajectory stably remains on the manifold and preserves the first integrals of the system. The idea is that given an initial point in the manifold we extend the dynamics from the manifold to its ambient Euclidean space and then modify the dynamics outside the intersection of the manifold and the level sets of the first integrals containing the initial point such that the intersection becomes a unique local attractor of the resultant dynamics. While the modified dynamics theoretically produces the same trajectory as the original dynamics, it yields a numerical trajectory that stably remains on the manifold and preserves the first integrals. The big merit of our method is that the modified dynamics can be integrated with any ordinary numerical integrator such as Euler or Runge-Kutta. We illustrate this method by applying it to three famous problems: the free rigid body, the Kepler problem and a perturbed Kepler problem with rotational symmetry. We also carry out simulation studies to demonstrate the excellence of our method and make comparisons with the standard projection method, a splitting method and Störmer-Verlet schemes.

  4. A multi-proxy chronological reconstruction of palaeosalinity in the eastern Limfjord, Denmark

    NASA Astrophysics Data System (ADS)

    Weiss, Gabriella; Reimer, Paula; Lewis, Jonathan

    2015-04-01

    The Jutland peninsula in northern Denmark is home to the Limfjord, one of the largest estuarine bodies of water in the region. Human inhabitance of the Limfjord's surrounding coastlines stretches back further than 7,800 cal BP, with anthropogenic influence on the landscape beginning approximately 6,000 cal BP. Understanding how the Limfjord as a system has changed throughout time is useful in comprehending subsistence patterns and anthropogenic influence. This research is part of a larger project aimed at discerning subsistence patterns and environmental change in the region. Following the Younger Dryas, as the Fennoscandian ice sheet began to melt, Denmark experienced isostatic rebound, which contributed to the complex sea level history in the region. Between ice melt and isostatic rebound, the Jutland peninsula experienced many transgression and regression events. Connections to surrounding seas have shifted throughout time, with most attention focused on the western connection of the Limfjord with the North Sea, which has experienced numerous closures and subsequent re-openings throughout the Holocene. Furthermore, the Limfjord-North Sea connection has been the focal point of research because of the west to east water flow in the system, and the present day higher salinity in the west compared to the east. Little to no consideration has been paid to the influence of the Kattegat and Baltic on the Limfjord until now. A 10m sediment core was taken from Sebbersund (near Nibe, Limfjord), along the connection between the Limfjord and the Kattegat in the east to understand how the eastern part of the system has changed and differed from changes observed in the west. The Sebbersund sequence spans a majority of the Holocene, from 9600 cal BP to 1030 cal BP, determined via radiocarbon dating of terrestrial macrofossils and bulk sediment. Over this time period palaeoenvironmental conditions were reconstructed through the use of geochemical analyses (δ13C, δ15N, C

  5. Geochemistry of a buried paleosol of Eemian age at Asklev, Denmark

    NASA Astrophysics Data System (ADS)

    Kristiansen, S. M.; Dalsgaard, K.; Kronborg, C.

    2009-04-01

    Buried soil surfaces are rich sources of information about past fauna, vegetation development, glacier dynamics, and climate variations However, in Denmark such former surfaces are very rare, as they rarely have escaped the intensive erosion below and in front of the Scandinavian ice sheets during the previous cold stages. Here we present a well-drained paleosol found extensively in a large gravel pit in the central part of Jutland, Denmark. The paleosol is suggested denoted the "Asklev paleosol". The Asklev paleosol is a well developed Podzol in sandy till of late Saalian age - the Asklev Till. The Asklev podsol is covered by fluvial sand in which another weaker podsol is present. Thermo-luminescense dating of the sand layer revealed an age of c. 100 ka BP, i.e. that the soil surface was buried in the early Weichelian. The surface was thus stable during the entire Eemain interglacial and subject to pedogenesis for >15.000 years. Discordantly resting on the fluvial sand is about 1.5 m of sandy till with an undisturbed grey lower part and a brown cryoturbated upper part. Fabric analyses from the lower grey part of the till reveal an ice movement from the SSE. This till is deposited during MIS 4 in middle Weichselian Thin sections from the Podzol' show that the buried A-horizons micromorphology is not fully comparable to present-day Podzols in the region as it has a well developed argillic horizon below despite the parent material low in clay (< 3%). In contrast to modern Danish Podzols it also retain ample evidence of burning (charcoal) and frost features (capping). The Asklev paleosol classify as a Placic Podzol, but is a typical bi-sequum with a Bt-horizon at depth. Its content of organic C is up to 38 mg C/g soil in the A-horizon, 8.4 mg C/g soil in the Bhs-horizon, which decreases to <1 mg C/g soil in the C-horizon. Carbon-to-nitrogen ratios range from 80 in the E-horizon to 25 in the C-horizon. Concentrations of heavy metals is low with maximums of 3.7 mg Ni

  6. Digital Mapping of Soil Organic Carbon Contents and Stocks in Denmark

    PubMed Central

    Adhikari, Kabindra; Hartemink, Alfred E.; Minasny, Budiman; Bou Kheir, Rania; Greve, Mette B.; Greve, Mogens H.

    2014-01-01

    Estimation of carbon contents and stocks are important for carbon sequestration, greenhouse gas emissions and national carbon balance inventories. For Denmark, we modeled the vertical distribution of soil organic carbon (SOC) and bulk density, and mapped its spatial distribution at five standard soil depth intervals (0−5, 5−15, 15−30, 30−60 and 60−100 cm) using 18 environmental variables as predictors. SOC distribution was influenced by precipitation, land use, soil type, wetland, elevation, wetness index, and multi-resolution index of valley bottom flatness. The highest average SOC content of 20 g kg−1 was reported for 0−5 cm soil, whereas there was on average 2.2 g SOC kg−1 at 60−100 cm depth. For SOC and bulk density prediction precision decreased with soil depth, and a standard error of 2.8 g kg−1 was found at 60−100 cm soil depth. Average SOC stock for 0−30 cm was 72 t ha−1 and in the top 1 m there was 120 t SOC ha−1. In total, the soils stored approximately 570 Tg C within the top 1 m. The soils under agriculture had the highest amount of carbon (444 Tg) followed by forest and semi-natural vegetation that contributed 11% of the total SOC stock. More than 60% of the total SOC stock was present in Podzols and Luvisols. Compared to previous estimates, our approach is more reliable as we adopted a robust quantification technique and mapped the spatial distribution of SOC stock and prediction uncertainty. The estimation was validated using common statistical indices and the data and high-resolution maps could be used for future soil carbon assessment and inventories. PMID:25137066

  7. Cancer Incidence among Patients with Anorexia Nervosa from Sweden, Denmark and Finland.

    PubMed

    Mellemkjaer, Lene; Papadopoulos, Fotios C; Pukkala, Eero; Ekbom, Anders; Gissler, Mika; Christensen, Jane; Olsen, Jørgen H

    2015-01-01

    A diet with restricted energy content reduces the occurrence of cancer in animal experiments. It is not known if the underlying mechanism also exists in human beings. To determine whether cancer incidence is reduced among patients with anorexia nervosa who tend to have a low intake of energy, we carried out a retrospective cohort study of 22 654 women and 1678 men diagnosed with anorexia nervosa at ages 10-50 years during 1968-2010 according to National Hospital Registers in Sweden, Denmark and Finland. The comparison group consisted of randomly selected persons from population registers who were similar to the anorexia nervosa patients in respect to sex, year of birth and place of residence. Patients and population comparisons were followed for cancer by linkage to Cancer Registries. Incidence rate ratios (IRR) were estimated using Poisson models. In total, 366 cases of cancer (excluding non-melanoma skin cancer) were seen among women with anorexia nervosa, and the IRR for all cancer sites was 0.97 (95% CI = 0.87-1.08) adjusted for age, parity and age at first child. There were 76 breast cancers corresponding to an adjusted IRR of 0.61 (95% CI = 0.49-0.77). Significantly increased IRRs were observed for esophageal, lung, and liver cancer. Among men with anorexia nervosa, there were 23 cases of cancer (age-adjusted IRR = 1.08; 95% CI = 0.71-1.66). There seems to be no general reduction in cancer occurrence among patients with anorexia nervosa, giving little support to the energy restriction hypothesis.

  8. Antimicrobial susceptibility patterns of thermophilic Campylobacter spp. from humans, pigs, cattle, and broilers in Denmark.

    PubMed Central

    Aarestrup, F M; Nielsen, E M; Madsen, M; Engberg, J

    1997-01-01

    The MICs of 16 antimicrobial agents were determined for 202 Campylobacter jejuni isolates, 123 Campylobacter coli isolates, and 6 Campylobacter lari isolates from humans and food animals in Denmark. The C. jejuni isolates originated from humans (75), broilers (95), cattle (29), and pigs (3); the C. coli isolates originated from humans (7), broilers (17), and pigs (99); and the C. lari isolates originated from broilers (5) and cattle (1). All isolates were susceptible to apramycin, neomycin, and gentamicin. Only a few C. jejuni isolates were resistant to one or more antimicrobial agents. Resistance to tetracycline was more common among C. jejuni isolates from humans (11%) than among C. jejuni isolates from animals (0 to 2%). More resistance to streptomycin was found among C. jejuni isolates from cattle (10%) than among those from humans (4%) or broilers (1%). A greater proportion of C. coli than of C. jejuni isolates were resistant to the other antimicrobial agents tested. Isolates were in most cases either coresistant to tylosin, spiramycin, and erythromycin or susceptible to all three antibiotics. More macrolide-resistant isolates were observed among C. coli isolates from swine (79%) than among C. coli isolates from broilers (18%) and humans (14%). Twenty-four percent of C. coli isolates from pigs were resistant to enrofloxacin, whereas 29% of C. coli isolates from humans and none from broilers were resistant. More resistance to streptomycin was observed among C. coli isolates from swine (48%) than among C. coli isolates from broilers (6%) or humans (0%). The six C. lari isolates were susceptible to all antimicrobial agents except ampicillin and nalidixic acid. This study showed that antimicrobial resistance was found only at relatively low frequencies among C. jejuni and C. lari isolates. Among C. coli isolates, especially from swine, there was a high level of resistance to macrolides and streptomycin. Furthermore, this study showed differences in the resistance

  9. Sexual dysfunctions and difficulties in denmark: prevalence and associated sociodemographic factors.

    PubMed

    Christensen, Birgitte S; Grønbaek, Morten; Osler, Merete; Pedersen, Bo V; Graugaard, Christian; Frisch, Morten

    2011-02-01

    Sexual dysfunctions and difficulties are common experiences that may impact importantly on the perceived quality of life, but prevalence estimates are highly sensitive to the definitions used. We used questionnaire data for 4415 sexually active Danes aged 16-95 years who participated in a national health and morbidity survey in 2005 to estimate the prevalence of sexual dysfunctions and difficulties and to identify associated sociodemographic factors. Overall, 11% (95% CI, 10-13%) of men and 11% (10-13%) of women reported at least one sexual dysfunction (i.e., a frequent sexual difficulty that was perceived as a problem) in the last year, while another 68% (66-70%) of men and 69% (67-71%) of women reported infrequent or less severe sexual difficulties. Estimated overall frequencies of sexual dysfunctions among men were: premature ejaculation (7%), erectile dysfunction (5%), anorgasmia (2%), and dyspareunia (0.1%); among women: lubrication insufficiency (7%), anorgasmia (6%), dyspareunia (3%), and vaginismus (0.4%). Highest frequencies of sexual dysfunction were seen in men above age 60 years and women below age 30 years or above age 50 years. In logistic regression analysis, indicators of economic hardship in the family were positively associated with sexual dysfunctions, notably among women. In conclusion, while a majority of sexually active adults in Denmark experience sexual difficulties with their partner once in a while, approximately one in nine suffer from frequent sexual difficulties that constitute a threat to their well-being. Sexual dysfunctions seem to be more common among persons who experience economic hardship in the family.

  10. Development of a semiquantitative food frequency questionnaire to assess food, energy and nutrient intake in Denmark.

    PubMed

    Overvad, K; Tjønneland, A; Haraldsdóttir, J; Ewertz, M; Jensen, O M

    1991-12-01

    Foods to be included in a Danish self-administered semiquantitative food frequency questionnaire were identified from food tables developed, together with data collected, for the survey 'Dietary habits in Denmark, 1985'. The questionnaire was to be used in a prospective study on diet, cancer and health, and the aim was to rank individuals with regard to intake of 19 different nutrients considered of prime importance in human carcinogenesis. The questionnaire for the dietary survey included 247 foods and recipes. From stepwise multiple regression analyses with the intake of each of the 19 nutrients as the dependent variable and the intake of the 247 foods and recipes as independent variables, the foods in the models explaining 90% of the between-person variability were considered for the final questionnaire. All relevant analyses were performed for the study group as a whole, for men and women separately, and in each gender for subgroups of energy intake. Taken together, the models explaining 90% of the between-person variability identified a total of 74 foods or recipes, which were important predictors of the intake of one or more of the nutrients considered. A few foods were excluded and a few foods were added to the final questionnaire based on common biological background information, and on information on foods providing important amounts of given nutrients, but which failed to contribute to regression analyses. The 92 foods and recipes, which were included in the final questionnaire provided altogether 81% of the average total supply of the nutrients.(ABSTRACT TRUNCATED AT 250 WORDS)

  11. Microstructure measurements and estimates of entrainment in the Denmark Strait overflow plume

    NASA Astrophysics Data System (ADS)

    Paka, V.; Zhurbas, V.; Rudels, B.; Quadfasel, D.; Korzh, A.; Delisi, D.

    2013-11-01

    To examine processes controlling the entrainment of ambient water into the Denmark Strait overflow (DSO) plume/gravity current, measurements of turbulent dissipation rate were carried out by a quasi-free-falling (tethered) microstructure profiler (MSP). The MSP was specifically designed to collect data on dissipation-scale turbulence and fine thermohaline stratification in an ocean layer located as deep as 3500 m. The task was to perform microstructure measurements in the DSO plume in the lower 300 m depth interval including the bottom mixed layer and the interfacial layer below the non-turbulent ambient water. The MSP was attached to a Rosette water sampler rack equipped with a SeaBird CTDO and an RD Instruments lowered acoustic Doppler current profiler (LADCP). At a chosen depth, the MSP was remotely released from the rack to perform measurements in a quasi-free-falling mode. Using the measured vertical profiles of dissipation, the entrainment rate as well as the bottom and interfacial stresses in the DSO plume were estimated at a location 200 km downstream of the sill at depths up to 1771 m. Dissipation-derived estimates of entrainment were found to be much smaller than bulk estimates of entrainment calculated from the downstream change of the mean properties in the plume, suggesting the lateral stirring due to mesoscale eddies rather than diapycnal mixing as the main contributor to entrainment. Dissipation-derived bottom stress estimates are argued to be roughly one third the magnitude of those derived from log velocity profiles. In the interfacial layer, the Ozmidov scale calculated from turbulence dissipation rate and buoyancy frequency was found to be linearly proportional to the overturning scale extracted from conventional CTD data (the Thorpe scale), with a proportionality constant of 0.76, and a correlation coefficient of 0.77.

  12. Microstructure measurements and estimates of entrainment in the Denmark Strait overflow plume

    NASA Astrophysics Data System (ADS)

    Paka, V.; Zhurbas, V.; Rudels, B.; Quadfasel, D.; Korzh, A.; Delisi, D.

    2013-07-01

    To examine processes controlling the entrainment of ambient water into the Denmark Strait overflow (DSO) plume/gravity current, measurements of turbulent dissipation rate were carried out by a quasi-free-falling (tethered) microstructure profiler (MSP). The MSP was specifically designed to collect data on dissipation-scale turbulence and fine thermohaline stratification in an ocean layer to depths of 3500 m. The task was to perform microstructure measurements in the DSO plume in the lower 300 m depth interval including the bottom mixed layer and the interfacial layer below the non-turbulent ambient water. The MSP was attached to a Rosette water sampler rack equipped with a SeaBird CTDO and an RD Instruments Lowered Acoustic Doppler Current Profiler (LADCP). At a chosen depth, the MSP was remotely released from the rack to perform measurements in a quasi-free-falling mode. Using the measured vertical profiles of dissipation, the entrainment rate as well as the bottom and interfacial stresses were estimated in the DSO plume at a location 200 km downstream of the sill at depths up to 1771 m. Dissipation-derived estimates of entrainment were found to be much smaller than bulk estimates of entrainment calculated from the downstream change of the mean properties in the plume, suggesting the lateral stirring due to meso-scale eddies rather than diapycnal mixing as the main contributor to entrainment. Dissipation-derived bottom stress estimates are argued to be roughly one-third the magnitude of those from log velocity profiles. In the interfacial layer, the Ozmidov scale calculated from turbulence dissipation rate and buoyancy frequency was found to be linearly proportional to the overturning scale extracted from conventional CTD data (the Thorpe scale), with a proportionality constant of 0.76, and a correlation coefficient of 0.77.

  13. Morphological and molecular analyses of larval taeniid species in small mammals from contrasting habitats in Denmark.

    PubMed

    Al-Sabi, M N S; Jensen, P M; Christensen, M U; Kapel, C M O

    2015-01-01

    Taeniid infections in intermediate hosts manifest themselves as extraintestinal larval stages which, in early development, lack species-specific characteristics. The inability to distinguish infections of zoonotic importance such as Echinococcus multilocularis from other taeniid infections that have mainly veterinary significance stimulated the development of species-specific molecular diagnostics. In this study, the prevalence of taeniid infections in potential intermediate hosts was evaluated using both morphological diagnosis and a newly described multiplex polymerase chain reaction (PCR) for species determination. Small mammals (N= 719) were trapped in three different types of habitats in north-east Zealand, Denmark. The sensitivity of the multiplex PCR (90.5%) exceeded that of morphological examination (57.9%) for identifying 95 taeniid infections. The use of the multiplex PCR resulted in higher prevalence rates due to improved detection of immature liver infections with Hydatigera taeniaeformis and Versteria mustelae, but did not affect the observed prevalence rates of peritoneal metacestodes of Taenia polyacantha. The prevalence of taeniid infections showed a significant difference according to habitat type, potentially identifying a 'sylvatic' transmission and an 'urban' transmission, with marked variation among different taeniid species. Versteria mustelae and T. polyacantha were more prevalent in rural forests, while infections with H. taeniaeformis were dominant in urban parks/forests and in residential and farm gardens. The multiplex PCR facilitated a better utilization of wildlife samples by yielding a higher number of definitive diagnoses of ambiguous taeniid infections in liver lesions, allowing for more accurate epidemiological data and, hence, a more accurate risk assessment.

  14. Ethnic variation in oral cleft occurrence in denmark 1981-2002.

    PubMed

    Pedersen, Grete Skøtt; Pedersen, Dorthe Almind; Mortensen, Laust Hvas; Andersen, Anne-Marie Nybo; Christensen, Kaare

    2014-11-01

    Objective : To examine differences in oral cleft (OC) occurrence based on maternal only and parental country of origin in Denmark from 1981 to 2002. Methods : Data on all live births from the Danish Medical Birth Register from 1981 to 2002 were linked with the Danish Facial Cleft Database. Cleft cases were categorized into isolated and nonisolated cleft lip with or without palate (CL/P) and cleft palate only (CP). Birth prevalence was calculated as cases per 1,000 live born children by maternal country of origin, world region, and mixed parental groups. Results : We identified 3094 OC cases among 1,319,426 live births. Danish-born women had an OC birth prevalence of 2.38 with a 95% confidence interval (CI) (2.29-2.47) and foreign-born women a significant lower prevalence of 2.01 (CI, 1.77-2.27). This difference was explained by a lower isolated CL/P birth prevalence among foreign-born women of 0.97 (CI, 0.81-1.16) versus 1.35 (CI, 1.28-1.41). No significant differences were seen for the remaining subtypes. Parents with the same foreign country of origin had a lower overall OC (1.63; CI, 1.35-1.94) and isolated CL/P (0.76; CI, 0.57-0.99) birth prevalence than Danish-born parents. This was not the case for any of the mixed parental groups. Overall and subtype prevalence rates varied according to maternal categories of world region. Conclusion : In this study we found differences in OC occurrence among all live births in the Danish population based on maternal country of origin from 1981 to 2002. Danish-born women had higher OC and isolated CL/P birth prevalence compared with foreign-born women.

  15. Estimated intake of intense sweeteners from non-alcoholic beverages in Denmark.

    PubMed

    Leth, T; Fabricius, N; Fagt, S

    2007-03-01

    In 1999, 116 samples of non-alcoholic beverages were analysed for the intense sweeteners cyclamate, acesulfame-K, aspartame and saccharin. High contents of cyclamate close to the maximum permitted level in 1999 of 400 mg l(-1) were found in many soft drinks. The estimated intake of the sweeteners was calculated using the Danish Dietary Survey based on 3098 persons aged 1-80 years. The estimated intake with 90th percentiles of 0.7, 4.0 and 0.2 mg kg(-1) body weight (bw) day(-1) for acesulfame-K, aspartame and saccharin, respectively, was much lower than the acceptable daily intake (ADI) values of 15, 40 and 2.5 mg kg(-1) bw day(-1) for acesulfame-K, aspartame and saccharin, respectively. However, the 90th percentile of the estimated cyclamate intake in 1-3 year olds was close to the ADI value of 7 mg kg(-1) bw day(-1); and the 99th percentile in the 1-10 year olds far exceeded the ADI value. Boys aged 7-10 years had a significantly higher estimated intake of cyclamate than girls. The 90th percentile for the whole population was 1.8 mg kg(-1) bw day(-1). After the reduction in the maximum permitted level in the European Union in 2004 from 400 to 250 mg cyclamate l-1, the exposure in Denmark can also be expected to be reduced. A new investigation in 2007 should demonstrate whether the problem with high cyclamate intake is now solved.

  16. Childhood Residential Mobility, Schizophrenia, and Bipolar Disorder: A Population-based Study in Denmark

    PubMed Central

    Paksarian, Diana; Eaton, William W.; Mortensen, Preben B.; Pedersen, Carsten B.

    2015-01-01

    Introduction: Childhood adversity is gaining increasing attention as a plausible etiological factor in the development of psychotic disorders. Childhood residential mobility is a potential risk factor that has received little attention in this context. Methods: We used registry data to estimate associations of residential mobility with narrow and broad schizophrenia and bipolar disorder across the course of childhood among 1.1 million individuals born in Denmark 1971–1991 and followed from age 15 through 2010. We assessed effect modification by sex, family history of mental disorder, the presence of siblings close in age, and distance moved. Results: In individual-year models adjusted for family history, urbanicity at birth, and parental age, mobility at all ages except the year of birth was associated with heightened risk of narrow and broad schizophrenia, and risk increased with age at moving and with the number of moves. Further adjustment for mobility at all ages 0–15 revealed associations mainly during the latter half of childhood, which were strongest during adolescence. Associations between mobility and bipolar disorder were fewer and weaker compared to schizophrenia. There was modest evidence of interaction with family history of psychiatric diagnosis, but little evidence for interaction by sex, the presence of closely-aged siblings, or distance moved. Schizophrenia associations did not appear attributable to increased mobility among adolescents with earlier onset. Conclusions: Mobility may increase risk for psychotic disorders, particularly schizophrenia. Children may be especially vulnerable during adolescence. Future research should investigate the importance of school changes and the potential for interaction with genetic risk. PMID:24903417

  17. Prevalence, birth incidence, and penetrance of von Hippel-Lindau disease (vHL) in Denmark.

    PubMed

    Binderup, Marie Louise Mølgaard; Galanakis, Michael; Budtz-Jørgensen, Esben; Kosteljanetz, Michael; Luise Bisgaard, Marie

    2017-02-01

    Von Hippel-Lindau disease (vHL) is a rare hereditary tumour predisposition with multiorgan involvement that is not always easily recognized. The disease is reported to be almost fully penetrant at age 60 years. Previous estimates of vHL prevalence and incidence are all regional and vary widely. Most are >20 years old and prone to selection bias because of inclusion of only clinically affected vHL patients who were diagnosed before genetic testing was available. In an unselected cohort of all known Danish carriers of a disease-causing VHL variant, we assessed vHL penetrance on a national basis. We further used national health registers to identify individuals who fulfilled the clinical diagnostic vHL criteria based on their registered diagnostic codes, but had not been diagnosed with vHL. We also assessed the medical histories of first-degree relatives to identify familial cases. This study gives the first national estimates of vHL prevalence (1 in 46 900 individuals) and birth incidence (1 in 27 300 live births). vHL has been underdiagnosed in Denmark, and as many as 25% of the overall vHL cohort (diagnosed+undiagnosed patients) have a missed diagnosis in spite of fulfilling the international diagnostic criteria. We found an overall penetrance of 87% at age 60 years. When considering only vHL patients who have not attended surveillance, 20% will still be asymptomatic at age 60 years. This should be considered in the context of genetic counselling, especially when assessing the risk of vHL in asymptomatic adult first-degree relatives who are often not genetically tested.

  18. Spatial and temporal variability of nitrous oxide emissions in a mixed farming landscape of Denmark

    NASA Astrophysics Data System (ADS)

    Schelde, K.; Cellier, P.; Bertolini, T.; Dalgaard, T.; Weidinger, T.; Theobald, M. R.; Olesen, J. E.

    2012-08-01

    Nitrous oxide (N2O) emissions from agricultural land are variable at the landscape scale due to variability in land use, management, soil type, and topography. A field experiment was carried out in a typical mixed farming landscape in Denmark, to investigate the main drivers of variations in N2O emissions, measured using static chambers. Measurements were made over a period of 20 months, and sampling was intensified during two weeks in spring 2009 when chambers were installed at ten locations or fields to cover different crops and topography and slurry was applied to three of the fields. N2O emissions during spring 2009 were relatively low, with maximum values below 20 ng N m-2 s-1. This applied to all land use types including winter grain crops, grasslands, meadows, and wetlands. Slurry application to wheat fields resulted in short-lived two-fold increases in emissions. The moderate N2O fluxes and their moderate response to slurry application were attributed to dry soil conditions due to the absence of rain during the four previous weeks. Cumulative annual emissions from two arable fields that were both fertilized with mineral fertilizer and manure were large (17 kg N2O-N ha-1 yr-1 and 5.5 kg N2O-N ha-1 yr-1) during the previous year when soil water conditions were favourable for N2O production during the first month following fertilizer application. Our findings confirm the importance of weather conditions as well as nitrogen management on N2O fluxes.

  19. Natural attenuation of xenobiotic organic compounds in a landfill leachate plume (Vejen, Denmark)

    NASA Astrophysics Data System (ADS)

    Baun, Anders; Reitzel, Lotte A.; Ledin, Anna; Christensen, Thomas H.; Bjerg, Poul L.

    2003-09-01

    Demonstration of natural attenuation of xenobiotic organic compounds (XOCs) in landfill leachate plumes is a difficult task and still an emerging discipline within groundwater remediation. One of the early studies was made at the Vejen Landfill in Denmark in the late 1980s, which suggested that natural attenuation of XOCs took place under strongly anaerobic conditions within the first 150 m of the leachate plume. This paper reports on a revisit to the same plume 10 years later. Within the strongly anaerobic part of the plume, 49 groundwater samples were characterized with respect to redox-sensitive species and XOCs. The analytical procedures have been developed further and more compounds and lower detection limits were observed this time. In addition, the samples were screened for degradation intermediates and for toxicity. The plume showed fairly stationary features over the 10-year period except that the XOC level as well as the level of chloride and nonvolatile organic carbon (NVOC) in the plume had decreased somewhat. Most of the compounds studied were subject to degradation in addition to dilution. Exceptions were benzene, the herbicide Mecoprop (MCPP), and NVOC. In the early study, NVOC seemed to degrade in the first part of the plume, but this was no longer the case. Benzyl succinic acid (BSA) was for the first time identified in a leachate plume as a direct indicator, and as the only intermediate of toluene degradation. Toxicity measurements on solid phase-extracted (SPE) samples revealed that toxic compounds not analytically identified were still present in the plume, suggesting that toxicity measurements could be helpful in assessing natural attenuation in leachate plumes.

  20. Angelman syndrome in Denmark. birth incidence, genetic findings, and age at diagnosis.

    PubMed

    Mertz, Line Granild Bie; Christensen, Rikke; Vogel, Ida; Hertz, Jens Michael; Nielsen, Karen Brøndum; Grønskov, Karen; Østergaard, John R

    2013-09-01

    Angelman syndrome (AS) is a neurogenetic disorder caused by loss of expression of the maternal imprinted gene UBE3A on chromosome 15q11.2-q13. Clinical features of AS include severe intellectual disability, a happy disposition, ataxia, mandibular prognatism, and epilepsy. Our objectives were to examine the birth incidence of AS in Denmark and to characterize the size of the 15q11.2-q13 deletions with 1,000K array CGH. In addition, we analyzed genotype differences in regard to age at diagnosis and investigated the occurrence of deletions/duplications outside the 15q11.2-q13 regions. We identified 51 patients with genetically verified AS, which corresponded to a birth incidence of 1:24,580 (95%CI: 1:23,727-1:25,433). Thirty-six patients showed a deletion; 13 had a Class I deletion and 20 had a Class II deletion. There was bimodal distribution of the BP3 breakpoint. Three patients had larger and atypical deletions, with distal breakpoints telomeric to BP3. Five patients had paternal uniparental disomy (pUPD) of chromosome 15, and four had a verified UBE3A mutation. Additional deletions/duplications outside the 15q11.2-q13 areas were demonstrated in half the participants. Six harbored more than one CNV. Mean age at diagnosis was 21 months (95%CI: 17-23 months) for children with a deletion and 46 months (95%CI: 36-55 months) for children with pUPD or a UBE3A mutation (P < 0.01). The presence of a CNV outside 15q11.2-q13 did not have an impact on age at diagnosis.

  1. GLANAM (Glaciated North Atlantic Margins): A Marie Curie Initial Training Network between Norway, the UK & Denmark

    NASA Astrophysics Data System (ADS)

    Petter Sejrup, Hans; Oline Hjelstuen, Berit

    2015-04-01

    GLANAM (Glaciated North Atlantic Margins) is an Initial Training Network (ITN) funded under the EU Marie Curie Programme. It comprises 10 research partners from Norway, UK and Denmark, including 7 University research teams, 1 industrial full partner and 2 industrial associate partners. The GLANAM network will employ and train 15 early career researchers (Fellows). The aim of GLANAM is to improve the career prospects and development of young researchers in both the public and private sector within the field of earth science, focusing on North Atlantic glaciated margins. The young scientists will perform multi-disciplinary research and receive training in geophysics, remote sensing, GIS, sedimentology, geomorphology, stratigraphy, geochemistry and numerical modeling through three interconnected work packages that collectively address knowledge gaps related to the large, glacial age, sedimentary depocentres on the North Atlantic margin. The 15 Fellows will work on projects that geographically extend from Ireland in the south to the High Arctic. Filling these gaps will not only result in major new insights regarding glacial age processes on continental margins in general, but will also provide paleoclimate information essential for understanding the role of marine-based ice sheets in the climate system and for the testing of climate models. GLANAM brings together leading European research groups working on glaciated margins in a coordinated and collaborative research and training project. Focusing on the North Atlantic margins, this coordinated approach will lead to a major advance in the understanding of glaciated margins more widely and will fundamentally strengthen European research and build capacity in this field.

  2. Population based study of rates of multiple pregnancies in Denmark, 1980-94.

    PubMed Central

    Westergaard, T.; Wohlfahrt, J.; Aaby, P.; Melbye, M.

    1997-01-01

    OBJECTIVE: To study trends in multiple pregnancies not explained by changes in maternal age and parity patterns. DESIGN: Trends in population based figures for multiple pregnancies in Denmark studied from complete national records on parity history and vital status. POPULATION: 497,979 Danish women and 803,019 pregnancies, 1980-94. MAIN OUTCOME MEASURES: National rates of multiple pregnancies, infant mortality, and stillbirths controlled for maternal age and parity. Special emphasis on primiparous women > or = 30 years of age, who are most likely to undergo fertility treatment. RESULTS: The national incidence of multiple pregnancies increased 1.7-fold during 1980-94, the increase primarily in 1989-94 and almost exclusively in primiparous women aged > or = 30 years, for whom the adjusted population based twinning rate increased 2.7-fold and the triplet rate 9.1-fold. During 1989-94, the adjusted yearly increase in multiple pregnancies for these women was 19% (95% confidence interval 16% to 21%) and in dizygotic twin pregnancies 25% (21% to 28%). The proportion of multiple births among infant deaths in primiparous women > or = 30 years increased from 11.5% to 26.9% during the study period. The total infant mortality, however, did not increase for these women because of a simultaneous significant decrease in infant mortality among singletons. CONCLUSIONS: A relatively small group of women has drastically changed the overall national rates of multiple pregnancies. The introduction of new treatments to enhance fertility has probably caused these changes and has also affected the otherwise decreasing trend in infant mortality. Consequently, the resources, both economical and otherwise, associated with these treatments go well beyond those invested in specific fertility enhancing treatments. PMID:9080993

  3. Cost-Effectiveness of Preventive Interventions to Reduce Alcohol Consumption in Denmark

    PubMed Central

    Holm, Astrid Ledgaard; Veerman, Lennert; Cobiac, Linda; Ekholm, Ola; Diderichsen, Finn

    2014-01-01

    Introduction Excessive alcohol consumption increases the risk of many diseases and injuries, and the Global Burden of Disease 2010 study estimated that 6% of the burden of disease in Denmark is due to alcohol consumption. Alcohol consumption thus places a considerable economic burden on society. Methods We analysed the cost-effectiveness of six interventions aimed at preventing alcohol abuse in the adult Danish population: 30% increased taxation, increased minimum legal drinking age, advertisement bans, limited hours of retail sales, and brief and longer individual interventions. Potential health effects were evaluated as changes in incidence, prevalence and mortality of alcohol-related diseases and injuries. Net costs were calculated as the sum of intervention costs and cost offsets related to treatment of alcohol-related outcomes, based on health care costs from Danish national registers. Cost-effectiveness was evaluated by calculating incremental cost-effectiveness ratios (ICERs) for each intervention. We also created an intervention pathway to determine the optimal sequence of interventions and their combined effects. Results Three of the analysed interventions (advertising bans, limited hours of retail sales and taxation) were cost-saving, and the remaining three interventions were all cost-effective. Net costs varied from € -17 million per year for advertisement ban to € 8 million for longer individual intervention. Effectiveness varied from 115 disability-adjusted life years (DALY) per year for minimum legal drinking age to 2,900 DALY for advertisement ban. The total annual effect if all interventions were implemented would be 7,300 DALY, with a net cost of € -30 million. Conclusion Our results show that interventions targeting the whole population were more effective than individual-focused interventions. A ban on alcohol advertising, limited hours of retail sale and increased taxation had the highest probability of being cost-saving and should thus

  4. Incidence Rates of Deliberate Self-Harm in Denmark 1994–2011

    PubMed Central

    2016-01-01

    Abstract. Background: The validity and reliability of suicide statistics have been questioned and few nationwide studies of deliberate self-harm have been presented. Aim: To calculate rates of deliberate self-harm in Denmark in order to investigate trends and assess the reliability of hospital records. Method: A register study based on all individuals recorded with an episode of deliberate self-harm or probable deliberate self-harm in nationwide registers during 1994–2011. Results: A substantial difference in the rates of deliberate self-harm and probable deliberate self-harm was noted for both genders. The average incidence rate of deliberate self-harm for women and men was 130.7 (95% CI = 129.6–131.8) per 100,000 and 86.9 (95% CI = 86.0–87.8) per 100,000, respectively. The rates of deliberate self-harm for women increased from 137.6 (95% CI = 132.9–142.3) per 100,000 in 1994 to 152.7 (95% CI = 147.8–157.5) in 2011. For a subgroup of younger women aged 15–24 years, an almost threefold increase was observed, IRR = 2.5 (95% CI = 2.4–2.7). The most frequently used method was self-poisoning. Conclusion: The rates of deliberate self-harm and probable deliberate self-harm differed significantly. An increased incidence of deliberate self-harm among young Danish women was observed, despite detection bias. An improved registration procedure of suicidal behavior is needed. PMID:27278571

  5. Life cycle assessment of waste incineration in Denmark and Italy using two LCA models.

    PubMed

    Turconi, Roberto; Butera, Stefania; Boldrin, Alessio; Grosso, Mario; Rigamonti, Lucia; Astrup, Thomas

    2011-10-01

    In Europe, about 20% of municipal solid waste is incinerated. Large differences can be found between northern and southern Europe regarding energy recovery efficiencies, flue gas cleaning technologies and residue management. Life-cycle assessment (LCA) of waste incineration often provides contradictory results if these local conditions are not properly accounted for. The importance of regional differences and site-specific data, and choice of LCA model itself, was evaluated by assessment of two waste incinerators representing northern and southern Europe (Denmark and Italy) based on two different LCA models (SimaPro and EASEWASTE). The results showed that assumptions and modelling approaches regarding energy recovery/substitution and direct air emissions were most critical. Differences in model design and model databases mainly had consequences for the toxicity-related impact categories. The overall environmental performance of the Danish system was better than the Italian, mainly because of higher heat recovery at the Danish plant. Flue gas cleaning at the Italian plant was, however, preferable to the Danish, indicating that efficient flue gas cleaning may provide significant benefits. Differences in waste composition between the two countries mainly affected global warming and human toxicity via water. Overall, SimaPro and EASEWASTE provided consistent ranking of the individual scenarios. However, important differences in results from the two models were related to differences in the databases and modelling approaches, in particular the possibility for modelling of waste-specific emissions affected the toxicity-related impact categories. The results clearly showed that the use of site-specific data was essential for the results.

  6. Transport and degradation of chlorofluorocarbons (CFCs) in the pyritic Rabis Creek aquifer, Denmark

    USGS Publications Warehouse

    Hinsby, K.; Hojberg, A.L.; Engesgaard, P.; Jensen, K.H.; Larsen, F.; Plummer, L.N.; Busenberg, E.

    2007-01-01

    Vertical profiles of the chlorofluorocarbons CFC-11, CFC-12, and CFC-113 penetrating aerobic and anaerobic parts of a shallow sandy aquifer show that the CFC gases are degraded in the <1 m thick transition zone from aerobic to anaerobic groundwater in a pyritic sand aquifer at Rabis Creek, Denmark. Two-dimensional solute transport simulations with either zero-order or first-order degradation in the anaerobic zone corroborate this interpretation. The transport model was previously calibrated against detailed tritium profiles in the same wells. First-order degradation is found to best match the observed CFC profiles yielding an approximate half-life of a few months for CFC-11. Degradation is not as clearly recognized for CFC-12 and CFC-113, but it may occur with rates corresponding to a half-life of a few years or more. Data indicate a geochemical control of the CFC concentration gradient at the redox front and that denitrification and denitrifiers are not of major importance for the observed CFC degradation. The responsible mechanism behind the observed degradation is not known but we suggest that reductive dehalogenation by surface-bound Fe(II) on pyrite possibly enhanced by the presence of Fe(III)-bearing weathering products (green rust) may be a plausible mechanism. The observed data and the performed simulations confirm the potential application of the CFC gases as age-dating tools in the aerobic part of the investigated aquifer, but also that CFC data must be analyzed carefully before it is used as a dating tool in reducing aquifers because degradation may have occurred. The use of multiple or alternative tracers should be considered in anaerobic environments. Copyright 2007 by the American Geophysical Union.

  7. A nitrogen budget for Denmark; developments between 1990 and 2010, and prospects for the future

    NASA Astrophysics Data System (ADS)

    Hutchings, N. J.; Nielsen, O.-K.; Dalgaard, T.; Mikkelsen, M. H.; Børgesen, C. D.; Thomsen, M.; Ellermann, T.; Højberg, A. L.; Mogensen, L.; Winther, M.

    2014-11-01

    A nitrogen (N) budget for Denmark has been developed for the years 1990 to 2010, describing the inputs and outputs at the national scale and the internal flows between relevant sectors of the economy. Satisfactorily closing the N budgets for some sectors of the economy was not possible, due to missing or contradictory information. The budgets were nevertheless considered sufficiently reliable to quantify the major flows. Agriculture was responsible for the majority of inputs, though fisheries and energy generation also made significant contributions. Agriculture was the main source of N input to the aquatic environment, whereas agriculture, energy generation and transport all contributed to emissions of reactive N gases to the atmosphere. Significant reductions in inputs of reactive N have been achieved during the 20 years, mainly by restricting the use of N for crop production and improving livestock feeding. This reduction has helped reduce nitrate leaching by about half. Measures to limit ammonia emissions from agriculture and mono-nitrogen oxides (NOx) emissions from energy generation and transport, has reduced gaseous emissions of reactive N. Much N flows through the food and feed processing industries and there is a cascade of N through the consumer to solid and liquid waste management systems. The budget was used to frame a discussion of the potential for further reductions in losses of reactive N to the environment. These will include increasing the recycling of N between economic sectors, increasing the need for the assessment of knock-on effects of interventions within the context of the national N cycle.

  8. Clinical experience and skills of physicians in hospital cardiac arrest teams in Denmark: a nationwide study

    PubMed Central

    Lauridsen, Kasper G; Schmidt, Anders S; Caap, Philip; Aagaard, Rasmus; Løfgren, Bo

    2017-01-01

    Background The quality of in-hospital resuscitation is poor and may be affected by the clinical experience and cardiopulmonary resuscitation (CPR) training. This study aimed to investigate the clinical experience, self-perceived skills, CPR training and knowledge of the guidelines on when to abandon resuscitation among physicians of cardiac arrest teams. Methods We performed a nationwide cross-sectional study in Denmark. Telephone interviews were conducted with physicians in the cardiac arrest teams in public somatic hospitals using a structured questionnaire. Results In total, 93 physicians (53% male) from 45 hospitals participated in the study. Median age was 34 (interquartile range: 30–39) years. Respondents were medical students working as locum physicians (5%), physicians in training (79%) and consultants (16%), and the median postgraduate clinical experience was 48 (19–87) months. Most respondents (92%) felt confident in treating a cardiac arrest, while fewer respondents felt confident in performing intubation (41%) and focused cardiac ultrasound (39%) during cardiac arrest. Median time since last CPR training was 4 (2–10) months, and 48% had attended a European Resuscitation Council (ERC) Advanced Life Support course. The majority (84%) felt confident in terminating resuscitation; however, only 9% were able to state the ERC guidelines on when to abandon resuscitation. Conclusion Physicians of Danish cardiac arrest teams are often inexperienced and do not feel competent performing important clinical skills during resuscitation. Less than half have attended an ERC Advanced Life Support course, and only very few physicians know the ERC guidelines on when to abandon resuscitation. PMID:28331374

  9. Digital mapping of soil organic carbon contents and stocks in Denmark.

    PubMed

    Adhikari, Kabindra; Hartemink, Alfred E; Minasny, Budiman; Bou Kheir, Rania; Greve, Mette B; Greve, Mogens H

    2014-01-01

    Estimation of carbon contents and stocks are important for carbon sequestration, greenhouse gas emissions and national carbon balance inventories. For Denmark, we modeled the vertical distribution of soil organic carbon (SOC) and bulk density, and mapped its spatial distribution at five standard soil depth intervals (0-5, 5-15, 15-30, 30-60 and 60-100 cm) using 18 environmental variables as predictors. SOC distribution was influenced by precipitation, land use, soil type, wetland, elevation, wetness index, and multi-resolution index of valley bottom flatness. The highest average SOC content of 20 g kg(-1) was reported for 0-5 cm soil, whereas there was on average 2.2 g SOC kg(-1) at 60-100 cm depth. For SOC and bulk density prediction precision decreased with soil depth, and a standard error of 2.8 g kg(-1) was found at 60-100 cm soil depth. Average SOC stock for 0-30 cm was 72 t ha(-1) and in the top 1 m there was 120 t SOC ha(-1). In total, the soils stored approximately 570 Tg C within the top 1 m. The soils under agriculture had the highest amount of carbon (444 Tg) followed by forest and semi-natural vegetation that contributed 11% of the total SOC stock. More than 60% of the total SOC stock was present in Podzols and Luvisols. Compared to previous estimates, our approach is more reliable as we adopted a robust quantification technique and mapped the spatial distribution of SOC stock and prediction uncertainty. The estimation was validated using common statistical indices and the data and high-resolution maps could be used for future soil carbon assessment and inventories.

  10. Algorithm linking patients and general practices in Denmark using the Danish National Health Service Register

    PubMed Central

    Kjaersgaard, Maiken Ina Siegismund; Vedsted, Peter; Parner, Erik Thorlund; Bech, Bodil Hammer; Vestergaard, Mogens; Flarup, Kaare Rud; Fenger-Grøn, Morten

    2016-01-01

    Background The patient list system in Denmark assigns virtually all residents to a general practice. Nevertheless, historical information on this link between patient and general practice is not readily available for research purposes. Objectives To develop, implement, and evaluate the performance of an algorithm linking individual patients to their general practice by using information from the Danish National Health Service Register and the Danish Civil Registration System. Materials and methods The National Health Service Register contains information on all services provided by general practitioners from 1990 and onward. On the basis of these data and information on migration history and death obtained from the Civil Registration System, we developed an algorithm that allocated patients to a general practice on a monthly basis. We evaluated the performance of the algorithm between 2002 and 2007. During this time period, we had access to information on the link between patients and general practices. Agreement was assessed by the proportion of months for which the algorithm allocated patients to the correct general practice. We also assessed the proportion of all patients in the patient list system for which the algorithm was able to suggest an allocation. Results The overall agreement between algorithm and patient lists was 98.6%. We found slightly higher agreement for women (98.8%) than for men (98.4%) and lower agreement in the age group 18–34 years (97.1%) compared to all other age groups (≥98.6%). The algorithm had assigned 83% of all patients in the patient list system after 1 year of follow-up, 91% after 2 years of follow-up, and peaked at 94% during the fourth year. Conclusion We developed an algorithm that enables valid and nearly complete linkage between patients and general practices. The algorithm performs better in subgroups of patients with high health care needs. The algorithm constitutes a valuable tool for primary health care research. PMID

  11. The tobacco problem in Denmark and the difficulties in implementing an organized plan of action.

    PubMed

    Egsmose, T

    1985-08-01

    In Denmark tobacco consumption has increased considerably during the last few decades. Almost 2 million people of a population of 5 million are smokers. Of the male population 48% are smokers, of the female population 46%. From 1981 to 1982 the cigarette consumption increased from 7,300 million to 8,000 million. Consumption of pipe tobacco increased slightly, whereas cigars and cigarillos were considerably reduced. The tobacco tax amounts to 6,500 million Dan. kr. annually (700 million US$). The tobacco industry's cost of marketing tobacco products are unknown, but advertising, for one thing, amounts to 25 million Dan.kr. annually (3 million US$), which is only a small fraction of the total cost of marketing. For comparison: On health information some 2 million Dan.kr. is spent annually by private associations. In 1970 and 1981 efforts were made to have a tobacco bill passed in the Danish Parliament-but with no success. Since 1972 there has been a gentleman's agreement between the ministry and the tobacco branch concerning the size and the content of tobacco advertising. The agreement was an evasive action initiated by the tobacco branch. During the tobacco bill debate in the Danish Parliament in 1981 the tobacco industry launched an aggressive and misleading advertising campaign in the large newspapers against the Minister of Interior. It says in the International Codes of Marketing Practice 1973 set forth by the International Chamber of Commerce: "all advertising should be legal, decent, honest and truthful" and "the advertisements should be prepared with due sense of social responsibility..".(ABSTRACT TRUNCATED AT 250 WORDS)

  12. Phenotypes, genotypes, and prevalence of congenital myopathies older than 5 years in Denmark

    PubMed Central

    Werlauff, Ulla; Duno, Morten; Vissing, John

    2017-01-01

    Objective: Congenital myopathy as a nosologic entity has long been recognized, but knowledge of overall and subtype prevalence and phenotype-genotype relationship is scarce, especially in the adult population. Methods: A national cohort of 107 patients ≥5 years diagnosed with congenital myopathy were prospectively assessed clinically, histologically, and genetically. Results: Twenty-five patients were excluded because of atypical features or alternative etiologies. The remaining 82 were on average 28 years old. Histologic examination revealed 14 (17%) with core disease, 15 (18%) centronuclear myopathy, 12 (15%) nemaline rods, 27 (33%) congenital fiber-type disproportion or type I predominance, and 14 (17%) nonspecific myopathic changes. Genetic etiology was identified in 46 patients (56.1%); 22.0% were heterozygous or compound heterozygous for mutations in RYR1, 7.3% had DNM2 mutations, and 7.3% NEB mutations. Less than 5% had mutations in ACTA1, TPM2/3, MTM1, TTN, SEPN1, or SC4NA. A genetic cause was established in 83% with specific histology (cores/rods/centronuclear myopathy) vs 29% with unspecific histology. The detailed clinical examination found gene-dependent discrepancies in the pattern of muscle affection and walking ability. Although walking ability was delayed in patients with ACTA1, TPM2/3, and RYR1 mutations, it was within normal limits in patients with NEB and DNM2 mutations. Conclusions: We found that overall, genetic and histologic prevalence of congenital myopathy in Denmark differs from previous retrospective reports. Less RYR1 and more DNM2 and NEB mutations and less core histology were present in our cohort. These differences may be explained by our prospective design, the older cohort of patients, and by differences in genetic background. PMID:28357410

  13. A coprological investigation of gastrointestinal and cardiopulmonary parasites in hunting dogs in Denmark.

    PubMed

    Al-Sabi, Mohammad N S; Kapel, Christian M O; Johansson, Anna; Espersen, Mia C; Koch, Jørgen; Willesen, Jakob L

    2013-09-23

    A coprological survey was conducted to investigate the prevalence of parasites infecting hunting dogs with no history of recent anthelmintic treatments and with no overt clinical manifestations of cardiopulmonary or gastrointestinal illness. The hunting dogs were recruited from four different areas in Denmark, and fecal samples were obtained in October and November, 2007. For detecting gastrointestinal parasites, samples (N=178) were examined by a commercial flotation kit (Fecalyzer(®) EVSCO, USA). For detection of cardiopulmonary parasites, samples (N=181) were collected on three consecutive days and examined using the Baermann method. Parasites were recovered from 22.1% of the hunting dogs: Angiostrongylus vasorum (2.2%), Toxocara canis (12.4%), Uncinaria stenocephala (7.3%), Taenia spp. (1.7%), Toxascaris leonina (0.6%), Coccidia (0.6%) and unidentified trematode eggs (1.1%). Infection with only one species of parasite was more common (89.5%) than infection with two species (10.5%). A multiple logistic regression model showed that prevalence of intestinal parasites was not influenced by age, gender or breed in adult dogs. There was a significantly higher prevalence of intestinal parasites in the densely populated area of the island Zealand compared with the less populated regions of the peninsular Jutland. The present study reports the first case of A. vasorum in a dog from Jutland. The dog had been visiting the endemic area of western Zealand, suggesting that translocation of sub-clinically infected dogs may contribute to introduction of A. vasorum into non-endemic areas.

  14. Self-reported quality care for knee osteoarthritis: comparisons across Denmark, Norway, Portugal and the UK

    PubMed Central

    Østerås, N; Jordan, K P; Clausen, B; Cordeiro, C; Dziedzic, K; Edwards, J; Grønhaug, G; Higginbottom, A; Lund, H; Pacheco, G; Pais, S; Hagen, K B

    2015-01-01

    Objectives To assess and compare patient perceived quality of osteoarthritis (OA) management in primary healthcare in Denmark, Norway, Portugal and the UK. Methods Participants consulting with clinical signs and symptoms of knee OA were identified in 30 general practices and invited to complete a cross-sectional survey including quality indicators (QI) for OA care. A QI was considered as eligible if the participant had checked ‘Yes’ or ‘No’, and as achieved if the participant had checked ‘Yes’ to the indicator. The median percentage (with IQR and range) of eligible QIs achieved by country was determined and compared in negative binominal regression analysis. Achievement of individual QIs by country was determined and compared using logistic regression analyses. Results A total of 354 participants self-reported QI achievement. The median percentage of eligible QIs achieved (checked ‘Yes’) was 48% (IQR 28%, 64%; range 0–100%) for the total sample with relatively similar medians across three of four countries. Achievement rates on individual QIs showed a large variation ranging from 11% (referral to services for losing weight) to 67% (information about the importance of exercise) with significant differences in achievement rates between the countries. Conclusions The results indicated a potential for improvement in OA care in all four countries, but for somewhat different aspects of OA care. By exploring these differences and comparing healthcare services, ideas may be generated on how the quality might be improved across nations. Larger studies are needed to confirm and further explore the findings. PMID:26535147

  15. Preventive home visits to older home-dwelling people in Denmark: are invitational procedures of importance?

    PubMed

    Ekmann, A; Vass, M; Avlund, K

    2010-11-01

    Since 1998 all municipalities in Denmark have been required by law to offer two annual preventive home visits to all home-dwelling citizens aged 75 or over. The influence of invitational procedures on acceptance rates has not been investigated. The aim of this study was to describe and investigate whether different invitational procedures were associated with first preventive home visit acceptance rates. The study was based on secondary analyses of data from the Danish Intervention Study on Preventive Home Visits. Data were collected from 1998 to 2002. Of the 4060 participants in the main study, 3245 reported receiving an offer for an identifiable preventive home visit, of whom 2399 (73.9%) provided complete data for the main analyses in the present study. Invitational procedures were categorised as: (1) a letter with a proposed date and time for the visit, (2) a visitor telephone call, and (3) a letter with encouragement to phone the visitor for appointment (letter without a proposed date). Covariates included sex, age, experience with preventive interventions, functional ability, self rated health, social relations and psychosocial characteristics. Statistical analyses included chi-square tests, and bi- and multivariable logistic regression analyses. Different invitational procedures were associated with first preventive home visit acceptance rates. Significantly more men (75.1%) than women (62.8%) declined the first preventive home visit regardless of the invitational procedure. Compared to 'letter with a proposed date', men had an odds ratio of 1.78 (95% CI: 1.16-2.74) for declining visits when 'telephone call' was used and an odds ratio 2.81 (95% CI: 1.79-4.40) when 'letter without a proposed date' was used as the invitational procedure. In women the odds ratios were 1.23 (95% CI: 0.91-1.68) and 1.87 (95% CI: 1.37-2.55), respectively.

  16. Controls on subsurface methane fluxes and shallow gas formation in Baltic Sea sediment (Aarhus Bay, Denmark)

    NASA Astrophysics Data System (ADS)

    Flury, Sabine; Røy, Hans; Dale, Andrew W.; Fossing, Henrik; Tóth, Zsuzsanna; Spiess, Volkhard; Jensen, Jørn Bo; Jørgensen, Bo Barker

    2016-09-01

    Shallow gas accumulates in coastal marine sediments when the burial rate of reactive organic matter beneath the sulfate zone is sufficiently high and the methanogenic zone is sufficiently deep. We investigated the controls on methane production and free methane gas accumulation along a 400 m seismo-acoustic transect across a sharp transition from gas-free into gas-bearing sediment in Aarhus Bay (Denmark). Twelve gravity cores were taken, in which the pore water was analyzed for inorganic solutes while rates of organic carbon mineralization were measured experimentally by 35SO42- radiotracer method. The thickness of organic-rich Holocene mud increased from 5 to 10 m along the transect concomitant with a shallowing of the depth of the sulfate-methane transition from >4 m to 2.5 m. In spite of drastic differences in the distribution of methane and sulfate in the sediment along the transect, there were only small differences in total mineralization, and methanogenesis was only equivalent to about 1% of sulfate reduction. Shallow gas appeared where the mud thickness exceeded 8-9 m. Rates of methanogenesis increased along the transect as did the upward diffusive flux of methane. Interestingly, the increase in the sedimentation rate and Holocene mud thickness had only a modest direct effect on methanogenesis rates in deep sediments. This increase in methane flux, however, triggered a shallowing of the sulfate-methane transition which resulted in a large increase in methanogenesis at the top of the methanogenic zone. Thus, our results demonstrate a positive feedback mechanism that causes a strong enhancement of methanogenesis and explains the apparently abrupt appearance of gas when a threshold thickness of organic-rich mud is exceeded.

  17. Classical integrability

    NASA Astrophysics Data System (ADS)

    Torrielli, Alessandro

    2016-08-01

    We review some essential aspects of classically integrable systems. The detailed outline of the sections consists of: 1. Introduction and motivation, with historical remarks; 2. Liouville theorem and action-angle variables, with examples (harmonic oscillator, Kepler problem); 3. Algebraic tools: Lax pairs, monodromy and transfer matrices, classical r-matrices and exchange relations, non-ultralocal Poisson brackets, with examples (non-linear Schrödinger model, principal chiral field); 4. Features of classical r-matrices: Belavin-Drinfeld theorems, analyticity properties, and lift of the classical structures to quantum groups; 5. Classical inverse scattering method to solve integrable differential equations: soliton solutions, spectral properties and the Gel’fand-Levitan-Marchenko equation, with examples (KdV equation, Sine-Gordon model). Prepared for the Durham Young Researchers Integrability School, organised by the GATIS network. This is part of a collection of lecture notes.

  18. The Male-Female Health-Survival Paradox and Sex Differences in Cohort Life Expectancy in Utah, Denmark and Sweden 1850-1910

    PubMed Central

    Lindahl-Jacobsen, Rune; Hanson, Heidi A.; Oksuzyan, Anna; Mineau, Geraldine P.; Christensen, Kaare; Smith, Ken R.

    2013-01-01

    Purpose In Utah, prevalence of unhealthy male risk behaviours are lower than in most other male populations while women experience higher mortality risk due to higher fertility rates. Therefore, we hypothesize that the Utah sex differential in mortality would be small and less than in Sweden and Denmark. Methods Life tables from Utah, Denmark and Sweden, were used to calculate cohort life expectancies for men and women born 1850-1910. Results The sex difference in cohort life expectancy was similar or larger in Utah when compared to Denmark and Sweden. The change over time in the sex differences in cohort life expectancy was approximately two years smaller for active Mormons in Utah than for other groups suggesting lifestyle as an important component for the overall change seen in cohort life expectancy. Sex differences in cohort life expectancy at age 50 were similar for individuals actively affiliated with the Church of Jesus Christ of Latter-day Saints and for Denmark and Sweden. Conclusions The hypothesis that a smaller sex difference in cohort life expectancies in Utah would be detected in relation to Denmark and Sweden was not supported. In Utah the male-female differences in life expectancy remain substantial pointing towards biological mechanisms, or other unmeasured risk factors. PMID:23453386

  19. The Integrated Hazard Analysis Integrator

    NASA Technical Reports Server (NTRS)

    Morris, A. Terry; Massie, Michael J.

    2009-01-01

    Hazard analysis addresses hazards that arise in the design, development, manufacturing, construction, facilities, transportation, operations and disposal activities associated with hardware, software, maintenance, operations and environments. An integrated hazard is an event or condition that is caused by or controlled by multiple systems, elements, or subsystems. Integrated hazard analysis (IHA) is especially daunting and ambitious for large, complex systems such as NASA s Constellation program which incorporates program, systems and element components that impact others (International Space Station, public, International Partners, etc.). An appropriate IHA should identify all hazards, causes, controls and verifications used to mitigate the risk of catastrophic loss of crew, vehicle and/or mission. Unfortunately, in the current age of increased technology dependence, there is the tendency to sometimes overlook the necessary and sufficient qualifications of the integrator, that is, the person/team that identifies the parts, analyzes the architectural structure, aligns the analysis with the program plan and then communicates/coordinates with large and small components, each contributing necessary hardware, software and/or information to prevent catastrophic loss. As viewed from both Challenger and Columbia accidents, lack of appropriate communication, management errors and lack of resources dedicated to safety were cited as major contributors to these fatalities. From the accident reports, it would appear that the organizational impact of managers, integrators and safety personnel contributes more significantly to mission success and mission failure than purely technological components. If this is so, then organizations who sincerely desire mission success must put as much effort in selecting managers and integrators as they do when designing the hardware, writing the software code and analyzing competitive proposals. This paper will discuss the necessary and

  20. Distribution of RET Mutations in Multiple Endocrine Neoplasia 2 in Denmark 1994–2014: A Nationwide Study

    PubMed Central

    Kroustrup, Jens Peter; Vestergaard, Peter; Stochholm, Kirstine; Poulsen, Per Løgstrup; Rasmussen, Åse Krogh; Feldt-Rasmussen, Ulla; Gaustadnes, Mette; Ørntoft, Torben Falck; Hansen, Thomas van Overeem; Nielsen, Finn Cilius; Brixen, Kim; Godballe, Christian; Frederiksen, Anja Lisbeth

    2017-01-01

    Background: Germline mutations of the REarranged during Transfection (RET) proto-oncogene cause multiple endocrine neoplasia 2 (MEN2). It is unclear whether the distribution of RET mutations varies among populations. The first nationwide study of the distribution of RET mutations was conducted, and the results were compared to those of other populations. Methods: This retrospective cohort study included 1583 patients who underwent RET gene testing in one of three centers covering all of Denmark between September 1994 and December 2014. Primary testing method was Sanger sequencing, which included exons 8–11 and 13–16. Mutations were defined according to the ARUP database July 1, 2016. Results: RET mutations were identified in 163 patients from 36 apparently unrelated families. Among the 36 families 13 (36.1%) carried mutations in codon 611, four (11.1%) in codon 618, three (8.3%) in codon 620, one (2.8%) in codon 631, six (16.7%) in codon 634, one (2.8%) in codon 790, one (2.8%) in codon 804, one (2.8%) in codon 852, one (2.8%) in codon 883, and five (13.9%) in codon 918. Among the 13 families with codon 611 mutations, 12 had the p.C611Y mutation. Conclusions: The distribution of RET mutations in Denmark appears to differ from that of other populations. Mutations in codon 611 were the most prevalent, followed by more frequently reported mutations. This might be due to a possible founder effect for the p.C611Y mutation. However, further studies are needed to find possible explanations for the skewed mutational spectrum in Denmark. PMID:27809725

  1. Surveillance of antimicrobial resistance in bacteria isolated from food animals to antimicrobial growth promoters and related therapeutic agents in Denmark.

    PubMed

    Aarestrup, F M; Bager, F; Jensen, N E; Madsen, M; Meyling, A; Wegener, H C

    1998-06-01

    This study was conducted to describe the occurrence of acquired resistance to antimicrobials used for growth promotion among bacteria isolated from swine, cattle and poultry in Denmark. Resistance to structurally related therapeutic agents was also examined. Three categories of bacteria were tested: 1) indicator bacteria (Escherichia coli, Enterococcus faecalis, Enterococcus faecium), 2) zoonotic bacteria (Campylobacter, Salmonella, Yersinia enterocolitica), and 3) animal pathogens (E. coli, Staphylococcus aureus, coagulase-negative staphylococci (CNS), Staphylococcus hyicus, Actinobacillus pleuropneumoniae). All antimicrobials used as growth promoters in Denmark and some structurally related therapeutic agents (in brackets) were included: Avilamycin, avoparcin (vancomycin), bacitracin, carbadox, flavomycin, monensin, olaquindox, salinomycin, spiramycin (erythromycin, lincomycin), tylosin (erythromycin, lincomycin), and virginiamycin (pristinamycin). Bacterial species intrinsically resistant to an antimicrobial were not tested towards that antimicrobial. Breakpoints for growth promoters were established by population distribution of the bacteria tested. A total of 2,372 bacterial isolates collected during October 1995 to September 1996 were included in the study. Acquired resistance to all currently used growth promoting antimicrobials was found. A frequent occurrence of resistance were observed to avilamycin, avoparcin, bacitracin, flavomycin, spiramycin, tylosin and virginiamycin, whereas resistance to carbadox, monensin, olaquindox and salinomycin was less frequent. The occurrence of resistance varied by animal origin and bacterial species. The highest levels of resistance was observed among enterococci, whereas less resistance was observed among zoonotic bacteria and bacteria pathogenic to animals. The association between the occurrence of resistance and the consumption of the antimicrobial is discussed. The results show the present level of resistance to

  2. An integrated model to predict the atmospheric spread of foot-and-mouth disease virus.

    PubMed Central

    Sørensen, J. H.; Mackay, D. K.; Jensen, C. O.; Donaldson, A. I.

    2000-01-01

    The application of a computer model called Rimpuff for simulating the airborne spread of foot-and-mouth disease (FMD) is described. Rimpuff is more sophisticated and accurate than other FMD simulation models previously described. It can be run on a desktop computer and performs analyses very quickly. It can be linked to a geographical information system and so the information generated can be integrated with geographical and demographical data for display in a format that can be easily assimilated and transmitted electronically. The system was validated using historical data from outbreaks of FMD in France and the UK in 1981, and from Denmark and the former German Democratic Republic (GDR) in 1982. A very good fit was obtained between the direction of the plumes of virus simulated by the model and the spread of disease from France to the UK in 1981. Although cattle in the UK were infected during the episode, the concentrations of airborne virus in the plumes simulated by the model were beneath the infectivity threshold for cattle. It was concluded from the analysis that the number of pigs infected in France, and therefore the source concentration of airborne virus, was probably much higher than was recorded at the time of the outbreaks. Analysis of the Denmark/GDR episode pointed to the possibility that the source of virus for the 1982 epidemic in Denmark could have been one or more unreported outbreaks involving pigs in the former GDR. PMID:10982082

  3. Numerical Integration

    ERIC Educational Resources Information Center

    Sozio, Gerry

    2009-01-01

    Senior secondary students cover numerical integration techniques in their mathematics courses. In particular, students would be familiar with the "midpoint rule," the elementary "trapezoidal rule" and "Simpson's rule." This article derives these techniques by methods which secondary students may not be familiar with and an approach that…

  4. Information Integrity

    ERIC Educational Resources Information Center

    Graves, Eric

    2013-01-01

    This dissertation introduces the concept of Information Integrity, which is the detection and possible correction of information manipulation by any intermediary node in a communication system. As networks continue to grow in complexity, information theoretic security has failed to keep pace. As a result many parties whom want to communicate,…

  5. Reappearance of Taenia ovis krabbei muscle cysts in a roe deer (Capreolus capreolus) in Denmark after 60+ years.

    PubMed

    Al-Sabi, Mohammad Nafi Solaiman; Chriél, Mariann; Holm, Elisabeth; Jensen, Tim Kåre; Ståhl, Marie; Enemark, Heidi Larsen

    2013-09-01

    The present report describes the reappearance of Taenia ovis krabbei in a roe deer from Denmark after more than 60 years. The cysticerci were isolated from the thigh muscle of the deer, and the diagnosis was based on histostological analysis, morphology of the rostellar-hooks as well as molecular typing of the mitochondrial cytochrome c oxidase I (cox1) gene. The exact definitive host was not revealed in this report, but domestic dogs may play a role of the definitive host in the area. This finding is of concern to hunters and deer meat producers, since the infected meat is usually condemned due to esthetic reasons.

  6. Integrated nanocatalysts.

    PubMed

    Zeng, Hua Chun

    2013-02-19

    Despite significant advancements in catalysis research, the prevailing catalyst technology remains largely an art rather than a science. Rapid development in the fields of nanotechnology and materials chemistry in the past few decades, however, provides us with a new capacity to re-examine existing catalyst design and processing methods. In recent years, "nanocatalysts" has become a term often used by the materials chemistry and catalysis community. It refers to heterogeneous catalysts at nanoscale dimensions. Similar to homogeneous catalysts, freestanding (unsupported) nanocatalysts are difficult to separate after use. Because of their small sizes, they are also likely to be cytotoxic and pose a threat to the environment and therefore may not be practical for industrial use. On the other hand, if they are supported on ordinary catalyst carriers, the nanocatalysts would then revert to act as conventional heterogeneous catalysts, since chemists have known active metal clusters or oxide particles in the nanoscale regime long before the nanotechnology era. To resolve this problem, we need new research directions and synthetic strategies. Important advancements in catalysis research now allow chemists to prepare catalytic materials with greater precision. By controlling particle composition, structure, shape, and dimension, researchers can move into the next phase of catalyst development if they can bridge these old and new technologies. In this regard, one way seems to be to integrate active nanostructured catalysts with boundary-defined catalyst supports that are "not-so-nano" in dimension. However, these supports still have available hierarchical pores and cavity spaces. In principle, these devices keep the essence of traditional "catalyst-plus-support" type systems. They also have the advantages of nanoscale engineering, which involves both high level design and integration processes in their fabrication. Besides this, the active components in these devices are

  7. Prevention of suicide and attempted suicide in Denmark. Epidemiological studies of suicide and intervention studies in selected risk groups.

    PubMed

    Nordentoft, Merete

    2007-11-01

    The suicide rates in Denmark have been declining during the last two decades. The decline was relatively larger among women than among men. All age groups experienced a decline except the very young with stable rates and the very old with increasing rates. The Universal, Selective, Indicated (USI) model recommended by Institute of Medicine was used as a framework for the thesis. Universal preventive interventions are directed toward the entire population; selective interventions are directed toward individuals who are at greater risk for suicidal behaviour; and indicated preventions are targeted at individuals who have already begun self-destructive behaviour. At the universal level, a review was carried out to highlight the association between availability of methods for suicide and suicide rate. There were mostly studies of firearms, and the conclusion of the review was that there was clear indication of restricted access to lethal means was associated with decline in suicide with that specific method, and in many cases also with overall suicide mortality. Restricting access is especially important for methods with high case fatality rate. Our own study indicated a beneficial effect on suicide rates of restrictions in access to barbiturates, dextropropoxyphen, domestic gas and car exhaust with high content of carbon monoxide. Although a range of other factors in the society might also be of importance, it was concluded that restrictions in access to dangerous means for suicide were likely to play an important role in reducing suicide rates in Denmark, especially for women. At the selective level, there are several important risk groups such as psychiatric patients, persons with alcohol and drug abuse, persons with newly diagnosed severe physical illness, all who previously attempted suicide, and groups of homeless, institutionalized, prisoners and other socially excluded persons. The thesis focused on homeless persons and psychiatric patients, especially patients

  8. Seismic architecture of the Chalk Group from onshore reflection data in eastern Denmark

    NASA Astrophysics Data System (ADS)

    Moreau, Julien; Anderskouv, Kresten; Boldreel, Lars Ole; Boussaha, Myriam; Nielsen, Lars; Stemmerik, Lars; Surlyk, Finn; Thibault, Nicolas

    2013-04-01

    The Upper Cretaceous-Danian chalk is well exposed in the 14 km long coastal cliff of Stevns Klint (eastern Denmark). The cliff is a world renowned for its spectacular exposure of the Cretaceous-Palaeogene boundary. Based on regional geological knowledge of the field and cores, the characteristics of the Chalk Group have been well constrained. Distinct sedimentary facies have been encountered; the sedimentology, the biostratigraphy, the diagenesis and the reservoir properties have been thoroughly investigated and reported. Stimulated by the intensive geological research, the field studies have been completed with the acquisition of an extensive set of subsurface data. The data include high resolution 2D multichannel seismics onshore and offshore, a seismic refraction profile, two entirely cored boreholes including wireline logs, GPR cross-hole tomography, thermographic analysis, etc. We intend to compile and merge the geological and geophysical datasets to investigate the variation of the Chalk Group properties and their signature in the subsurface. In this communication, the seismic reflection data are being analysed. Very high resolution litho-, bio- and cyclostratigraphy can be correlated with the seismic stratigraphy. Several seismic facies are identified in the Chalk Group: the 'transparent' (white chalk), the stratified (marl-chalk alternations), the crudely stratified (flint-rich chalk) and the hummocky (bryozoan mounds). The units notably vary in thickness at a relatively small scale. The variations confirm the complex shelf organisation which was highly influenced by bottom currents. In addition to the stratigraphic observations, peculiar deformation structures can be recognised. The area has been supposedly tectonically stable since deposition as the coastal cliff lacks fault offset but the succession has been uplifted of c. 1 km. The main fracture patterns are associated with the recent unloading of the ice, opening shallow horizontal fractures

  9. Biogeochemistry and biodiversity of methane cycling in subsurface marine sediments (Skagerrak, Denmark).

    PubMed

    Parkes, R John; Cragg, Barry A; Banning, Natasha; Brock, Fiona; Webster, Gordon; Fry, John C; Hornibrook, Ed; Pancost, Richard D; Kelly, Sam; Knab, Nina; Jørgensen, Bo B; Rinna, Joachim; Weightman, Andrew J

    2007-05-01

    This biogeochemical, molecular genetic and lipid biomarker study of sediments ( approximately 4 m cores) from the Skagerrak (Denmark) investigated methane cycling in a sediment with a clear sulfate-methane-transition zone (SMTZ) and where CH(4) supply was by diffusion, rather than by advection, as in more commonly studied seep sites. Sulfate reduction removed sulfate by 0.7 m and CH(4) accumulated below. (14)C-radiotracer measurements demonstrated active H(2)/CO(2) and acetate methanogenesis and anaerobic oxidation of CH(4) (AOM). Maximum AOM rates occurred near the SMTZ ( approximately 3 nmol cm(-3) day(-1) at 0.75 m) but also continued deeper, overall, at much lower rates. Maximum rates of H(2)/CO(2) and acetate methanogenesis occurred below the SMTZ but H(2)/CO(2) methanogenesis rates were x 10 those of acetate methanogenesis, and this was consistent with initial values of (13)C-depleted CH(4) (delta(13)C c.-80 per thousand). Areal AOM and methanogenic rates were similar ( approximately 1.7 mmol m(-2) day(-1)), hence, CH(4) flux is finely balanced. A 16S rRNA gene library from 1.39 m combined with methanogen (T-RFLP), bacterial (16S rRNA DGGE) and lipid biomarker depth profiles showed the presence of populations similar to some seep sites: ANME-2a (dominant), ANME-3, Methanomicrobiales, Methanosaeta Archaea, with abundance changes with depth corresponding to changes in activities and sulfate-reducing bacteria (SRB). Below the SMTZ to approximately 1.7 m CH(4) became progressively more (13)C depleted (delta(13)C -82 per thousand) indicating a zone of CH(4) recycling which was consistent with the presence of (13)C-depleted archaeol (delta(13)C -55 per thousand). Pore water acetate concentrations decreased in this zone (to approximately 5 microM), suggesting that H(2), not acetate, was an important CH(4) cycling intermediate. The potential biomarkers for AOM-associated SRB, non-isoprenoidal ether lipids, increased below the SMTZ but this distribution reflected 16S

  10. Factors associated with usage of antimicrobials in commercial mink (Neovison vison) production in Denmark.

    PubMed

    Jensen, V F; Sommer, H M; Struve, T; Clausen, J; Chriél, M

    2016-04-01

    The American mink (Neovison vison) is used for commercial fur production in Denmark. In recent years, antimicrobial prescription for Danish mink has been increasing. In this study, the patterns and trends in antimicrobial use in mink were described and a multi-variable variance analysis was carried out with the objective of identifying risk factors for antimicrobial use on herd level. The study was based on register data for 2007-2012. Information on antimicrobial use was obtained from the national database VetStat, monitoring all medicinal products used for animals on prescription level. Data on microbiological feed quality was obtained from the Voluntary Feed Control under the Mink producers Organization, and data on herd size and the relation between farm and feed producer was obtained from the registers at Kopenhagen Fur, based on yearly reporting from the mink producers. Descriptive analysis showed a clear significant effect of season on antimicrobial use, with a peak in "treatment proportions", TP (defined daily doses per kg biomass-days) in May, around the time of whelping, and a high level in the following months. In autumn, a minor peak in antimicrobial use occurred throughout the study period. From 2007 to 2011, a 102% increase in annual antimicrobial TP was noted; on herd level, the increase was associated with an increasing frequency of prescription, and a decrease in the amounts prescribed in months with prescription. A binomial model showed that on herd level, the annual number of months with antimicrobial prescription was significantly (p<0.01) affected by feed producer, veterinarian, disease (specific laboratory diagnosis) infection, herd size and year, with an interaction between feed producer and year. A log-normal model showed that in months with antimicrobial use, the TP on herd level was significantly (p<0.001) affected by year, month (season), feed producer, feed quality score, veterinarian, herd size and laboratory confirmed diagnosis of

  11. Stirring by deep cyclones and the evolution of Denmark strait overflow water observed at line W

    NASA Astrophysics Data System (ADS)

    Andres, M.; Toole, J. M.; Torres, D. J.; Smethie, W. M.; Joyce, T. M.; Curry, R. G.

    2016-03-01

    Shipboard velocity and water property data from 18 transects across the North Atlantic Deep Western Boundary Current (DWBC) near 40 °N are examined to study the evolution of the Denmark Strait Overflow Water (DSOW) component of the DWBC and mixing between DSOW and the interior. The examined transects along Line W - which stretches from the continental shelf south of New England to Bermuda - were made between 1994 and 2014. The shipboard data comprise measurements at regular stations of velocity from lowered acoustic Doppler current profilers, CTD profiles and trace gas chlorofluorocarbon (CFC) concentrations from bottle samples at discrete depths. Comparison of the Line W velocity sections with concurrent sea surface height maps from satellite altimetry indicates that large cyclones in the deep ocean accompany intermittent quasi-stationary meander troughs in the Gulf Stream path at Line W. A composite of 5 velocity sections along Line W suggests that a typical cyclone reaches swirl speeds of greater than 30 cm s-1 at 3400-m depth and has a radius (distance between the center and the maximum velocity) of 75 km. Tracer data suggest that these cyclones affect not only the deep velocity structure along Line W, but also provide a mechanism for water exchange between the DWBC's DSOW and the interior. Vigorous exchange is corroborated by a mismatch in the CFC-11:CFC-12 and CFC-113:CFC-12 ratio ages calculated for DSOW at Line W. During the most recent 5-year period (2010-2014), a decrease in DSOW density has been driven by warming (increasing by almost 0.1 °C) as salinity has increased only slightly (by 0.003, which is close to the 0.002 uncertainty of the measurements). The abyssal ocean offshore of the DWBC and Gulf Stream and deeper than 3000-m depth has freshened at a rate of 6×10-4 yr-1 since at least 2003. Density here remains nearly unchanged over this period, due to temperature compensation, though a linear cooling trend in the abyssal ocean (to compensate the

  12. Predicting patient ‘cost blooms’ in Denmark: a longitudinal population-based study

    PubMed Central

    Tamang, Suzanne; Milstein, Arnold; Sørensen, Henrik Toft; Pedersen, Lars; Mackey, Lester; Betterton, Jean-Raymond; Janson, Lucas; Shah, Nigam

    2017-01-01

    Objectives To compare the ability of standard versus enhanced models to predict future high-cost patients, especially those who move from a lower to the upper decile of per capita healthcare expenditures within 1 year—that is, ‘cost bloomers’. Design We developed alternative models to predict being in the upper decile of healthcare expenditures in year 2 of a sample, based on data from year 1. Our 6 alternative models ranged from a standard cost-prediction model with 4 variables (ie, traditional model features), to our largest enhanced model with 1053 non-traditional model features. To quantify any increases in predictive power that enhanced models achieved over standard tools, we compared the prospective predictive performance of each model. Participants and Setting We used the population of Western Denmark between 2004 and 2011 (2 146 801 individuals) to predict future high-cost patients and characterise high-cost patient subgroups. Using the most recent 2-year period (2010–2011) for model evaluation, our whole-population model used a cohort of 1 557 950 individuals with a full year of active residency in year 1 (2010). Our cost-bloom model excluded the 155 795 individuals who were already high cost at the population level in year 1, resulting in 1 402 155 individuals for prediction of cost bloomers in year 2 (2011). Primary outcome measures Using unseen data from a future year, we evaluated each model's prospective predictive performance by calculating the ratio of predicted high-cost patient expenditures to the actual high-cost patient expenditures in Year 2—that is, cost capture. Results Our best enhanced model achieved a 21% and 30% improvement in cost capture over a standard diagnosis-based model for predicting population-level high-cost patients and cost bloomers, respectively. Conclusions In combination with modern statistical learning methods for analysing large data sets, models enhanced with a large and diverse set of features

  13. Effects of climate variability on saltwater intrusions in coastal aquifers in Southern Denmark

    NASA Astrophysics Data System (ADS)

    Meyer, Rena; Sonnenborg, Torben; Engesgaard, Peter; Høyer, Anne-Sophie; Jørgensen, Flemming; Hisnby, Klaus; Hansen, Birgitte; Jensen, Jørn Bo; Piotrowski, Jan A.

    2016-04-01

    As in many other regions of the world fresh water supply in Denmark is based on groundwater resources. Aquifers in the low-lying areas in the south-west of Jutland are particularly vulnerable to saltwater intrusions which are likely to intensify due to relative sea level rise. To understand the dynamics and development of this complex flow system, the initial hydrodynamic conditions imposed by the last Scandinavian Ice Sheet (SIS) must be taken into account. The whole region has undergone changes in climatic and hydraulic conditions within the last 15000 years that may show influence on the present flow conditions. It is likely that the groundwater-flow dynamics, driven by the postglacial hydraulic head drop and the relative sea level rise are not yet equilibrated. Enhanced by the potential future sea level rise due to climate change, contamination of fresh-water aquifers will continue. The 2800-km2 - large coast-to-coast study area located in the southern part of Jutland was partly overridden by the Weichselian ice sheet. Geophysical and geological mapping shows salt water intrusions up to 20 km inland from the present coast. Based on a geological voxel model spanning Miocene through Quaternary deposits a large-scale 3D numerical groundwater flow and salt water transport model has been developed. It includes density-driven flow and simulates the distribution of the current saltwater intrusions and their evolution during the last 15000 years. Particle tracking and direct age simulations are performed to identify recharge areas and constrain groundwater ages. The simulated ages are compared to ages derived from isotope analysis of groundwater samples both from Miocene and Quaternary aquifers. The origin of the groundwater is determined based on isotopic and chemical composition. Additionally, heavy noble gas analysis is carried out to estimate recharge temperatures and mechanisms at locations where groundwater recharge during the last glaciation is indicated. This

  14. Settling Velocity Specific SOC Distribution along Hillslopes - A field investigation in Denmark

    NASA Astrophysics Data System (ADS)

    Kuhn, N. J.; Hu, Y.

    2015-12-01

    The net effects of soil erosion by water, as a sink or source of atmospheric CO2, are decisively affected by the spatial re-distribution and stability of eroded soil organic carbon (SOC). The deposition position of eroded SOC, into terrestrial or aquatic systems, is actually decided by the transport distances of soil fractions where the SOC is stored. In theory, the transport distances of aggregated soil fractions are related to their settling velocities under given layer conditions. Yet, little field investigation has been conducted to examine the actual movement of eroded soil fractions along hillslopes, let alone the re-distribution pattern of functional SOC fractions. Eroding sandy soils and sediment were sampled after a series of rainfall events from different topographic positions along a slope on a freshly seeded cropland in Jutland, Denmark. All the soil samples from difference topographic positions along the slope were fractionated into five settling classes using a settling tube apparatus. The SOC content, 13C signature, and C:N ratios of all settling fractions were measured. Our results show that: 1) the spatial distribution of soil settling classes along the slope clearly shows a coarsening effect at the deposition area immediately below the eroding slope, followed by a fining trend on the deposition area at the slope tail. This proves the validity of the conceptual model in Starr et al. 2000 to predict SOC redistribution patterns along eroding hillslopes. 2) The isotopically enriched 13C on the slope back suggests greater decomposition rates possibly experienced by eroded SOC during transport, while the pronounced respiration rates at the slope tail indicate a great potential of CO2 emissions after deposition. Overall, our results illustrate that immediate deposition of fast settling soil fractions, and the thus induced preferential deposition of SOC at foot slope and potential CO2 emissions during transport, must be appropriately accounted for in

  15. Micro-scale modelling of energy fluxes over a small Fluxnet forest site in Denmark

    NASA Astrophysics Data System (ADS)

    Sogachev, A.; Dellwik, E.; Boegh, E.

    2012-12-01

    Most forests, especially in Europe, are too small to fulfil strict fetch requirements associated with idealized flux observations in undisturbed, homogeneous flow. As a consequence of limited fetch, the flux measured above the canopy will often deviate from the source strength underlying the measurements. Since representative measurements focused on heterogeneous effects are scarce because of demanding experimental arrangements the numerical modelling are often recruited for analysis of these deviations. During the last years the atmospheric boundary layer (ABL) model SCADIS (scalar distribution model; Sogachev et al., 2002, Tellus 54B, 784-819) has been successfully applied especially in the region adjacent to a forest edge in order to improve flux data interpretation. Most of the analyses were done for the neutral case and in two-dimensional mode. When analyzing the effect of a forest edge on both flow and passive scalar properties, numerical studies showed that sources located on a soil surface are major contributors to wave-like flux behavior downwind of the leading edge, and that it is important to distinguish the effects of ground sources from those of the foliage. In the present work, we apply the SCADIS model with enhanced turbulence closure including buoyancy for investigation of the daily course of energy fluxes over patchy forested terrain in Denmark, where the model is used in three-dimensional mode. The modelling results (with 50 m horizontal resolution) are in good qualitative agreement with high-resolution (60 m and 120 m) remote-sensing data of the effective surface temperature of the area near the site in focus: the forested areas are colder in daytime and warmer in night time than surrounding open areas. In contrast to the remote sensing approach, SCADIS provides the information about spatial distribution of latent and sensible heat vertical fluxes in the whole ABL. Topography and forest edge effects result in vertical turbulent fluxes that

  16. Integrated Fluorescence

    NASA Technical Reports Server (NTRS)

    Tuma, Margaret (Inventor); Gruhlke, Russell W. (Inventor)

    1998-01-01

    A detection method is integrated with a filtering method and an enhancement method to create a fluorescence sensor that can be miniaturized. The fluorescence sensor comprises a thin film geometry including a waveguide layer, a metal film layer and sensor layer. The thin film geometry of the fluorescence sensor allows the detection of fluorescent radiation over a narrow wavelength interval. This enables wavelength discrimination and eliminates the detection of unwanted light from unknown or spurious sources.

  17. Unchanged incidence and increased survival in children with neuroblastoma in Denmark 1981–2000: a population-based study

    PubMed Central

    Schroeder, H; Wacher, J; Larsson, H; Rosthoej, S; Rechnitzer, C; Pedersen, B L; Carlsen, N L T

    2009-01-01

    Treatment results for neuroblastoma in Denmark have been poorer than in other Nordic countries, so we investigated whether a change in incidence, stage distribution and survival had occurred between 1981 and 2000. Clinical data were retrieved from the medical charts of 160 children <15 years of age with extra-cranial neuroblastoma (n=139) or ganglioneuroblastoma (n=21) diagnosed in Denmark between 1981 and 2000. The minimal follow-up time was 52 months. Statistical analyses were performed in STATA. The incidence was 8.55 per million children below 15 years of age (world standard 9.6) and 42.6 per million children below 12 months of age, and it has remained unchanged since 1970. The median age at diagnosis was 27 months. In all, 32% of the children were aged below 12 months at diagnosis, 53% had metastatic disease and in 12% the diagnosis was made incidentally. Prognostic factors such as age, stage and site of primary tumour were the same as in other studies and did not change. During the study period, the mortality rate decreased steadily, and the 5-year survival rate increased from 38% in 1981–1985 to 59% in 1996–2000, corresponding to the level found in other Western countries. Increased survival was also seen in children with metastatic disease. Participation in international studies, better supportive care and possibly postoperative autologous stem cell transplantation may have contributed to the increased survival. PMID:19223904

  18. Mycobacterium tuberculosis outbreak strain of Danish origin spreading at worrying rates among greenland-born persons in Denmark and Greenland.

    PubMed

    Lillebaek, T; Andersen, A B; Rasmussen, E M; Kamper-Jørgensen, Z; Pedersen, M K; Bjorn-Mortensen, K; Ladefoged, K; Thomsen, V O

    2013-12-01

    Transmission of Mycobacterium tuberculosis continues at high rates among Greenland-born persons in Greenland and Denmark, with 203 and 450 notified cases per 10(5) population, respectively, in the year 2010. Here, we document that the predominant M. tuberculosis outbreak strain C2/1112-15 of Danish origin has been transmitted to Greenland-born persons in Denmark and subsequently to Greenland, where it is spreading at worrying rates and adding to the already heavy tuberculosis burden in this population group. It is now clear that the C2/1112-15 strain is able to gain new territories using a new population group as the "vehicle." Thus, it might have the ability to spread even further, considering the potential clinical consequences of strain diversity such as that seen in the widely spread Beijing genotype. The introduction of the predominant M. tuberculosis outbreak strain C2/1112-15 into the Arctic circumpolar region is a worrying tendency which deserves attention. We need to monitor whether this strain already has, or will, spread to other countries.

  19. Ethnicity and children's diets: the practices and perceptions of mothers in two minority ethnic groups in Denmark.

    PubMed

    Nielsen, Annemette; Krasnik, Allan; Holm, Lotte

    2015-10-01

    This study explores concerns and dilemmas connected with diet, health and child-feeding in families with ethnic minority background. The aim is to contribute to better targeting of dietary advice to ethnic minority parents in Denmark. Four focus group interviews were carried out with mothers of children between 4 months and 2 and a half years who were descendants of Turkish or Pakistani immigrants. The focus groups investigated: (1) everyday feeding practices; (2) values and concerns behind food choice; (3) social and cultural norms influencing feeding and eating practices; (4) experienced dilemmas in dietary change; and (5) sources of nutritional advice. Public health authorities in Denmark tend to link diet-related health problems among ethnic minority populations with their ethnic identity, dichotomising ethnic and Danish dietary habits. This may overlook values and concerns other than those related to ethnicity that are sometimes more important in determining food habits. The present study found that child-feeding practices were shaped by two main aims: (1) securing and improving child health; and (2) ensuring multi-cultural eating competence in children. The results confirm that ethnic distinctions do matter in the concerns and dilemmas mothers experience when feeding their children, but they also challenge the health authorities' reliance on dichotomies in promoting health among immigrant families. The participants' ethnic self-identification through food practices did not refer primarily to the birthplaces of their parents. Rather, it was context dependent and directed simultaneously towards majority and minority culture.

  20. Wet deposition of pesticides and nitrophenols at two sites in Denmark: measurements and contributions from regional sources.

    PubMed

    Asman, Willem A H; Jørgensen, Andreas; Bossi, Rossana; Vejrup, Karl V; Mogensen, Betty Bügel; Glasius, Marianne

    2005-05-01

    The concentrations of selected pesticides, of some of their degradation products and nitrophenols in rain were measured at two stations in Denmark in the period January 2000-July 2001. Forty compounds were quantified at least at one station during at least one sampling period. Additionally 17 compounds could be detected but not quantified, and 22 compounds could not be detected at all. The highest depositions of pesticides were observed for pendimethalin and desethylterbuthylazine, which is a degradation product of terbuthylazine. The deposition of the nitrophenols 2,4-dinitrophenol, DNOC, 3-methyl-4-nitrophenol was much higher than that of pesticides. The deposition of 2,4-dinitrophenol was e.g. up to a factor of 40 higher than that of pendimethalin. Atrazine, chloridazon, 2,4-D, dieldrin, disulfoton, fenitrothion, isoproturon, lenacil, metazachlor and propachlor were found in precipitation, although these pesticides are not allowed in Denmark. It can therefore be concluded that they came from abroad and have been transported over at least 60-80 km. For some of these compounds the transport distance is much longer.

  1. How are clinicians involved in EHR planning? A process analysis case study of a region in Denmark.

    PubMed

    Høstgaard, Anna Marie; Bertelsen, Pernille; Nøhr, Christian

    2010-01-01

    Experience shows that to achieve a successful implementation of EHR clinicians must obtain joint ownership of the decisions made during the EHR-process. The EHR planning process in the Region of North Jutland, Denmark was studied with the aim of answering the question; "Why are not all Danish physicians overjoyed by the introduction of EHR? A case study was carried out from Oct. 2003 till April 2006 using process analysis. The EHR project management's strategy meant that there was no workload reduction. This was seen as one of the main barriers for the physicians to achieve real influence. History shows that clinician's on the one hand and administrators on the other have different perceptions of the purpose of the patient record and that they both have struggled to influence this definition. To date, the administrators have won the battle. This was the major reason for the approach chosen for the EHR planning process in North Jutland, Denmark. It explains the conditions made available for the physicians, which led to their role being reduced to clinical consultants--rather than real participants.

  2. Compiling a national resistivity atlas of Denmark based on airborne and ground-based transient electromagnetic data

    NASA Astrophysics Data System (ADS)

    Barfod, Adrian A. S.; Møller, Ingelise; Christiansen, Anders V.

    2016-11-01

    We present a large-scale study of the petrophysical relationship of resistivities obtained from densely sampled ground-based and airborne transient electromagnetic surveys and lithological information from boreholes. The overriding aim of this study is to develop a framework for examining the resistivity-lithology relationship in a statistical manner and apply this framework to gain a better description of the large-scale resistivity structures of the subsurface. In Denmark very large and extensive datasets are available through the national geophysical and borehole databases, GERDA and JUPITER respectively. In a 10 by 10 km grid, these data are compiled into histograms of resistivity versus lithology. To do this, the geophysical data are interpolated to the position of the boreholes, which allows for a lithological categorization of the interpolated resistivity values, yielding different histograms for a set of desired lithological categories. By applying the proposed algorithm to all available boreholes and airborne and ground-based transient electromagnetic data we build nation-wide maps of the resistivity-lithology relationships in Denmark. The presented Resistivity Atlas reveals varying patterns in the large-scale resistivity-lithology relations, reflecting geological details such as available source material for tills. The resistivity maps also reveal a clear ambiguity in the resistivity values for different lithologies. The Resistivity Atlas is highly useful when geophysical data are to be used for geological or hydrological modeling.

  3. Quality assessment of cataract surgery in Denmark - risk of retinal detachment and postoperative endophthalmitis.

    PubMed

    Bjerrum, Søren Solborg

    2015-03-01

    The main purpose of this thesis was to examine whether the Danish National Patient Registry (NPR) could be used to monitor and assess the quality of cataract surgery in Denmark by studying the risks of two serious postoperative complications following cataract surgery - retinal detachment (RD) and postoperative endophthalmitis (PE). The thesis consists of four retrospective studies. In the first study (paper I), we used data from the NPR in the calendar period 2000-2010 to investigate the risk of pseudophakic retinal detachment (PRD) using the fellow non-operated eyes of the patients as reference. The study showed that over a 10-year study period, the risk of PRD was increased by a factor of 4.2 irrespective of sex and age. The risk of PRD was highest in the first part of the postoperative period and then gradually decreased but remained statistically significantly higher than the risk of RD in non-operated fellow eyes up to 10 years after cataract surgery. The epidemiology of RD in the non-operated fellow eyes was different from the epidemiology of RD in the background population as young men had the highest risk of RD in the non-operated fellow eyes. This means that the absolute risk of PRD was highest for young men because they had a higher risk of RD before they underwent cataract surgery. In the second study (paper II), we used data from the NPR and reviewed patient charts to assess the risk of PE after cataract surgery performed in public eye departments and private hospitals/clinics in the study period 2002-2010. The overall risk of PE among the seven public eye departments was 0.36 per 1000 registered cataract operations, and the PE risk among the departments was homogeneous. The overall risk of PE among the 28 private hospitals/clinics was 0.73 per 1000 registered cataract operations, and the risk among the private hospitals/clinics was heterogeneous. Most private hospitals/clinics had a risk of PE that was lower than or similar to the risk of PE after

  4. ACCELERATION INTEGRATOR

    DOEpatents

    Pope, K.E.

    1958-01-01

    This patent relates to an improved acceleration integrator and more particularly to apparatus of this nature which is gyrostabilized. The device may be used to sense the attainment by an airborne vehicle of a predetermined velocitv or distance along a given vector path. In its broad aspects, the acceleration integrator utilizes a magnetized element rotatable driven by a synchronous motor and having a cylin drical flux gap and a restrained eddy- current drag cap deposed to move into the gap. The angular velocity imparted to the rotatable cap shaft is transmitted in a positive manner to the magnetized element through a servo feedback loop. The resultant angular velocity of tae cap is proportional to the acceleration of the housing in this manner and means may be used to measure the velocity and operate switches at a pre-set magnitude. To make the above-described dcvice sensitive to acceleration in only one direction the magnetized element forms the spinning inertia element of a free gyroscope, and the outer housing functions as a gimbal of a gyroscope.

  5. Large volcanic eruptions and the PETM: Geochemistry from the Fur Formation, Denmark

    NASA Astrophysics Data System (ADS)

    Jones, Morgan; Svensen, Henrik; Tegner, Christian; Planke, Sverre; Willumsen, Pi

    2015-04-01

    The opening of the North Atlantic Ocean during the early Cenozoic was accompanied by substantial volcanism that resulted in the deposition of numerous ash layers over much of northern Europe. This volcanism was contemporaneous with the extreme greenhouse climate of the Palaeocene-Eocene Thermal Maximum (PETM), and is therefore of particular interest for volcanism-climate interactions. The island of Fur, northern Denmark, contains abundant outcrops of volcanic ash layers deposited in a shallow marine environment. Over 179 distinct ash horizons (those greater than ~1 cm are numbered #-39 to #+140) are found within the ~60 m thick Fur Formation. The ash layers are predominantly black and composed of volcanic glass particles ranging from silt to sand in size. Each bed is normally graded and lacks any evidence of significant reworking. There were no volcanoes in the vicinity of Fur during this time, and the outcrops are >700 km from the break-up axis, indicating that at least some of the ash layers were formed during very large eruptions and transported a long way from the source volcanoes. A few thick grey ash layers (e.g. #-33 and #+19) are believed to have originated from volcanoes in East Greenland. Here we present geochemical data from two key sections within the Fur Formation, a beach section at Stolleklint where ashes #-34 to #-31 are exposed, and a quarry section at Jenshøj that covers ashes #+17 to #+35. The #-33 and #+19 ashes are both prominent marker horizons around 15-20 cm thick. The Stolleklint section is clay rich while the quarry section is dominated by diatomite. At Stolleklint, bulk rock total organic carbon (TOC) δ13C values throughout a 1.5 m section are relatively steady at -30.7 to -31.7 o typical of the carbon isotope excursion values of the PETM at Fur. Just above ash layer #-33, δ13C = -27.9 o characteristic of post-PETM values. The bulk rock TOC is high, 1.5 to 4 wt. %. The post-PETM quarry section is much poorer in organic material (0

  6. Models of Financing the Continuing Vocational Training of Employees and Unemployed. Documentation of a LEONARDO-Project in Cooperation with Denmark, Germany, the Netherlands and Norway.

    ERIC Educational Resources Information Center

    Grunewald, Uwe, Ed.; Moraal, Dick, Ed.

    This document contains papers from an international project in which models of financing the continuing vocational training (CVT) in Denmark, Germany, the Netherlands, and Norway were identified and examined. The following are among the papers included: "Important Results of the LEONARDO-Project (contributions by all project-partners)";…

  7. Draft Genome Sequences of Two Kocuria Isolates, K. salsicia G1 and K. rhizophila G2, Isolated from a Slaughterhouse in Denmark

    PubMed Central

    Herschend, Jakob; Raghupathi, Prem K.; Røder, Henriette L.; Sørensen, Søren J.

    2016-01-01

    We report here the draft genome sequences of Kocuria salsicia G1 and Kocuria rhizophila G2, which were isolated from a meat chopper at a small slaughterhouse in Denmark. The two annotated genomes are 2.99 Mb and 2.88 Mb in size, respectively. PMID:27034479

  8. Draft Genome Sequences of Two Kocuria Isolates, K. salsicia G1 and K. rhizophila G2, Isolated from a Slaughterhouse in Denmark.

    PubMed

    Herschend, Jakob; Raghupathi, Prem K; Røder, Henriette L; Sørensen, Søren J; Burmølle, Mette

    2016-03-31

    We report here the draft genome sequences ofKocuria salsiciaG1 andKocuria rhizophilaG2, which were isolated from a meat chopper at a small slaughterhouse in Denmark. The two annotated genomes are 2.99 Mb and 2.88 Mb in size, respectively.

  9. The International Symposium on Music in Medicine, Education, and Therapy for the Handicapped (3rd, Ebeltoft, Denmark, July 31-August 5, 1983).

    ERIC Educational Resources Information Center

    Pratt, Rosalie Rebollo, Ed.

    Eighteen author-contributed papers are presented from a 1983 Ebeltoft, Denmark conference on clinical uses of music for disabled and chronically ill persons. The following authors and titles are represented: "Music Perception" (J. Davies); "Central Auditory Dysfunction: Implications for Music and the Handicapped" (C. DeFosse and R. Price);…

  10. ADOLESCENTS IN TWO SOCIETIES--PEERS, SCHOOL, AND FAMILY IN THE UNITED STATES AND DENMARK. FINAL REPORT. VOLUMES I AND II.

    ERIC Educational Resources Information Center

    KANDEL, DENISE B.; AND OTHERS

    THE PURPOSES OF THIS STUDY WERE (1) TO EXAMINE THE RELATIVE INFLUENCE UPON ADOLESCENTS OF PEERS AND FAMILIES, (2) TO COMPARE THESE INFLUENCES IN TWO SOCIETIES, THE UNITED STATES AND DENMARK, AND (3) TO DESCRIBE THE INTERNAL STRUCTURE AND OPERATION OF ADOLESCENT SUBCULTURES IN THE TWO SOCIETIES. DATA WERE COLLECTED ON ALL STUDENTS IN THREE AMERICAN…

  11. What Do the General Population Know, Believe and Feel about Individuals with Autism and Schizophrenia: Results from a Comparative Survey in Denmark

    ERIC Educational Resources Information Center

    Jensen, Christina Mohr; Martens, Caroline Skat; Nikolajsen, Nanna Dagmar; Skytt Gregersen, Trine; Heckmann Marx, Nanna; Goldberg Frederiksen, Mette; Hansen, Martine Stene

    2016-01-01

    Few studies investigate what members of the general population know about individuals with autism. Only one study has previously investigated how beliefs about autism differ from those about other psychiatric disorders. This study surveyed a convenience sample of the general adult population, within the Northern Region of Denmark, about their…

  12. Reforming Vocational Didactics by Implementing a New VET Teacher Education in Denmark: Tensions and Challenges Reflected in Interviews with Vocational College Teachers

    ERIC Educational Resources Information Center

    Duch, Henriette; Andreasen, Karen E.

    2015-01-01

    A new education program, Diploma of Vocational Pedagogy, has recently been implemented in Denmark to upskill vocational college teachers and improve didactics at VET colleges in general. Among many challenges, vocational college teachers have to adapt their pedagogy to a large number of students from backgrounds with no tradition for education.…

  13. Hepatitis B prevalence in Denmark - an estimate based on nationwide registers and a national screening programme, as on 31 December 2007.

    PubMed

    Hansen, N; Hay, G; Cowan, S; Jepsen, P; Bygum Krarup, H; Obel, N; Weis, N; Brehm Christensen, P

    2013-11-21

    The prevalence of chronic hepatitis B virus (HBV) infection in Denmark is not clear. The primary aim of this study was to estimate the prevalence of chronic HBV infection in Denmark. The capture–recapture method was used to estimate the total population diagnosed with chronic HBV infection in Denmark using four nationwide registers. The population with undiagnosed chronic HBV infection was estimated by incorporating data from a two-year nationwide HBsAg screening programme in pregnant women. We identified 4,466 individuals with chronic HBV infection in the four registers until the end of 2007, and the capture–recapture estimate of the total population diagnosed with chronic hepatitis B was 7,112 (95% confidence interval (CI): 6,953–10,747). Only 17% of the identified patients attended recommended clinical care according to national guidelines. Including undiagnosed patients, the current population alive with HBV infection was 10,668 (95% CI: 10,224–16,164), corresponding to a prevalence of 0.24% (95% CI: 0.23–0.37%) in the Danish population older than 15 years. The estimated prevalence of chronic HBV infection among adults in Denmark was lower than reported from other northern European countries. Only half of the infected population had been diagnosed, and a minority attended specialised clinical care.

  14. Proceedings of the Nordic Conference on Science and Technology Education: The Challenge of the Future (Karlslunde Strand, Denmark, May 8-12, 1985).

    ERIC Educational Resources Information Center

    Thulstrup, Erik W., Ed.

    The Nordic Conference of 1985 was convened for the purpose of fostering cooperation between science and technology educators within different fields and at different levels, with approximately 40 science and technology educators from Finland, Norway, Sweden, Denmark, India, the United States, and Yugoslavia participating. This report contains 27…

  15. Poly- and perfluoroalkyl substances (PFASs) in raw and drinking water - current situation in Sweden, Denmark and Germany

    NASA Astrophysics Data System (ADS)

    Banzhaf, Stefan; Bester, Kai; Filipovic, Marko; Lewis, Jeffrey; Licha, Tobias; Sparrenbom, Charlotte; Barthel, Roland

    2016-04-01

    Poly- and perfluoroalkyl substances (PFASs) are a group of anthropogenic environmental pollutants which have been used and produced for more than 60 years. PFASs are used for multiple industrial purposes, e.g. as water repellent on clothing, leather, and paper and as firefighting foam. The most well studied PFASs subgroup are perfluoroalkyl acids (PFAA). Two PFAAs of particular interest are perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA). These are the most studied homologues which are ubiquitously detected in the aquatic environment, wildlife and humans. Some PFASs are recognized as being potentially toxic for both animals and humans (e.g. PFOS), whereas the majority has not been thoroughly studied yet regarding their toxicity. PFAAs are highly mobile once present in the aquatic environment. Currently, they are not eliminated during conventional wastewater or drinking water treatment and therefore pose a severe threat for drinking water supply. We reviewed the current occurrence of PFAAs in the surface and groundwater and legal situation of PFAAs in Sweden, Denmark and Germany. Although first detections of PFAAs were reported in the early 2000s, PFASs only recently attracted huge media attention raising public concern. In Sweden, for instance, several public waterworks needed to cease operation due to high PFASs concentrations in drinking water. Moreover, threshold values for drinking water are under discussion and a first preliminary guiding value for PFOS was recently presented as a first step (Pettersson et al., 2015). Germany only defined a guiding value for the sum of PFOS and PFOA in drinking water so far (Dieter, 2011). Limits of 0.3 μg/L PFOA and 0.1 μg/L PFOS and PFOSA each have been suggested in Denmark (MST, 2015). In summary, none of the three countries has defined a clear threshold value for any PFAS compound in drinking water so far. This is of huge concern as PFASs are detected at increasing rates while it remains unclear when

  16. Coding ill-defined and unknown cause of death is 13 times more frequent in Denmark than in Finland.

    PubMed

    Ylijoki-Sørensen, Seija; Sajantila, Antti; Lalu, Kaisa; Bøggild, Henrik; Boldsen, Jesper Lier; Boel, Lene Warner Thorup

    2014-11-01

    Exact cause and manner of death determination improves legislative safety for the individual and for society and guides aspects of national public health. In the International Classification of Diseases, codes R00-R99 are used for "symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified" designated as "ill-defined" or "with unknown etiology". The World Health Organisation recommends avoiding the use of ill-defined and unknown causes of death in the death certificate as this terminology does not give any information concerning the possible conditions that led to the death. Thus, the aim of the study was, firstly, to analyse the frequencies of R00-R99-coded deaths in mortality statistics in Finland and in Denmark and, secondly, to compare these and the methods used to investigate the cause of death. To do so, we extracted a random 90% sample of the Finnish death certificates and 100% of the Danish certificates from the national mortality registries for 2000, 2005 and 2010. Subsequently, we analysed the frequencies of forensic and medical autopsies and external clinical examinations of the bodies in R00-R99-coded deaths. The use of R00-R99 codes was significantly higher in Denmark than in Finland; OR 18.6 (95% CI 15.3-22.4; p<0.001) for 2000, OR 9.5 (95% CI 8.0-11.3; p<0.001) for 2005 and OR 13.2 (95% CI 11.1-15.7; p<0.001) for 2010. More than 80% of Danish deaths with R00-R99 codes were over 70 years of age at the time of death. Forensic autopsy was performed in 88.3% of Finnish R00-R99-coded deaths, whereas only 3.5% of Danish R00-R99-coded deaths were investigated with forensic or medical autopsy. The codes that were most used in both countries were R96-R99, meaning "unknown cause of death". In Finland, all of these deaths were investigated with a forensic autopsy. Our study suggests that if all deaths in all age groups with unclear cause of death were systematically investigated with a forensic autopsy, only 2-3/1000 deaths per year

  17. "It Really Makes Good Sense": The Role of Outcome Evaluation in Aphasia Therapy in Denmark

    ERIC Educational Resources Information Center

    Isaksen, Jytte Kjaergaard

    2014-01-01

    Background: Measuring or evaluating outcomes is a common activity for many speech-language therapists (SLTs). A major focus has been on external forces claiming outcome evaluation to optimize quality and the use of resources without integrating the viewpoints of SLTs. Aims: To identify the purpose of outcome evaluation by letting SLTs identify not…

  18. Problem-Based Learning in Social Work Education: Students' Experiences in Denmark

    ERIC Educational Resources Information Center

    Monrad, Merete; Mølholt, Anne-Kirstine

    2017-01-01

    Problem-based learning (PBL) constitutes a promising way of integrating academia and social work practice because PBL fosters engagement with real-life problems and enhances important skills needed in social work practice. However, little attention has been given to social work students' experiences of PBL. In this article we address this gap by…

  19. Design principles for achieving integrated healthcare information systems.

    PubMed

    Jensen, Tina Blegind

    2013-03-01

    Achieving integrated healthcare information systems has become a common goal for many countries in their pursuit of obtaining coordinated and comprehensive healthcare services. This article focuses on how a small local project termed 'Standardized pull of patient data' expanded and is now used on a large scale providing a majority of hospitals, general practitioners and citizens across Denmark with the possibility of accessing healthcare data from different electronic patient record systems and other systems. I build on design theory for information infrastructures, as presented by Hanseth and Lyytinen, to examine the design principles that facilitated this smallscale project to expand and become widespread. As a result of my findings, I outline three lessons learned that emphasize: (i) principles of flexibility, (ii) expansion from the installed base through modular strategies and (iii) identification of key healthcare actors to provide them with immediate benefits.

  20. Universal screening for hepatitis B among pregnant women led to 96% vaccination coverage among newborns of HBsAg positive mothers in Denmark.

    PubMed

    Harder, Katja Majlund; Cowan, Susan; Eriksen, Mette Brandt; Krarup, Henrik B; Christensen, Peer Brehm

    2011-11-21

    In Denmark selective screening programs of pregnant women for hepatitis B missed 30-50% of high-risk groups and in late 2005 a universal screening of pregnant women for HBsAg was implemented. During a 2-year period a prospective enhanced surveillance of the universal screening was performed to examine the effectiveness of universal HBV-screening of pregnant women and HBV-immunizations of their newborn, and to provide a prevalence-estimate for HBV in Denmark. On a opt out basis all women in Denmark attending antenatal care were tested for hepatitis B serology. Vaccination data of the newborns and households of HBsAg positive pregnant women were assembled. Among 140,376 HBsAg tests of pregnant women, 371 (0.26%) were positive. The prevalence among women of Danish origin was 0.012% and 2.74% among foreign born women, highest for women from Southeast Asia (14.5%). Genotype C was the most prevalent (37%) and 13% had a HBVDNA ≥10(8) IU/ml. The prevalence estimate of chronic hepatitis B in Denmark was 0.2-0.3% in the general population. Among children born within the project period, 96% received vaccination at birth compared to 50% of siblings born prior to universal screening. During 3 years of passive follow-up two transmissions (0.5%) have been notified. Among children born of the positive mothers prior to the trial-period 7.3% had been notified. Thus the prevalence of HBV positive mothers has more than doubled in Denmark over the last 40 years, but among women of Danish origin it has decreased 10-fold. By replacing selective screening with universal, identification of newborns in need of HBV-immunization was increased from 50% to almost complete coverage, and also identifies mothers with high viral load for evaluation of pre-term treatment to interrupt in utero transmission.

  1. Drinking Alone? The Effect of an Alcohol Treatment Program on Relationship Stability for Convicted Drunk Drivers in Denmark

    PubMed Central

    Andersen, Signe Hald

    2016-01-01

    This article tests whether an alcohol treatment program for drunk drivers in Denmark increased the stability of their relationships with spouses or cohabiting partners. The treatment program, implemented in 1990, allowed a group of offenders to avoid prison and participate in a rehabilitation program. I use it here as a natural experiment, exploiting a rich administrative dataset to show that the program marginally increases offenders’ relationship stability. I also test whether increased relationship stability observed among the treated offenders results from their pardon from prison or from their participation in the rehabilitation program. Results suggest that the rehabilitation program drives the effect. These findings contribute to the literature on what alternative sanctions could be offered to offenders to improve their long-term social outcomes. PMID:27471323

  2. TYCHO Brahe's Empiric Methods, His Instruments, His Sudden Escape from Denmark and a New Theory About His Death

    NASA Astrophysics Data System (ADS)

    Thykier, C.

    1992-07-01

    Tycho Brahe (1546-1601) was born a noble being, a son of Otto Brahe, and a member of the Royal Danish Council. Very early he developed a great interest in science and especially astronomy. In 1575 Tycho visited the learned Prince Wilhelm II in Kassel. Here he was inspired by the famous instrument maker Burgi to build new precise astronomical instruments, and on the recommendation of Wilhelm King Frederic II of Denmark was given the island Hven (which at that time belonged to Denmark) as an entailed estate. At 26 years old, Tycho became famous for his work DE NOVA STELLA on the supernova that brightened up in 1572, and since this phenomenon kept its position fixed among the stars, it immediately invalidated the Aristotelian dogma of the invariability of the fixed-star world. In 1577 Tycho observed the great comet and followed its celestial motion by means of a quadrant and a sextant. He then came to the conclusion that the comet orbit moved far out among the planets, in contradiction to the Aristotelian dogma of the crystal spheres for the planets. However, Tycho's great contribution to science was his construction of the observatory buildings Uraniborg and Stjerneborg ("Star Castle") with their equipment of ancient sighting instruments and his use of these instruments without telescopes for observations of the planets over a period of almost 20 years. Tycho's work is collected in 15 volumes, OPERA OMNIA by J. L. E. Dreyer. Tycho also mapped Hven correctly and he triangulated both sides of Oresund relative to Hven. When Tycho moved to Prague in 1599 he lived there for a couple of years and met Kepler who became his assistant and collaborator. Kepler was the one who analyzed Tycho's material and derived the Keplerian laws for the motions of the planets. On this basis Newton derived the law of gravitation. Tycho Brahe has been considered the father of modern empirical science. In 1596 he was accused of negligence of his administrative duties and several other things

  3. Trilosporoides platessae gen. et sp. n. (Myxozoa: Multivalvulida) in the plaice Pleuronectes platessa (Teleostei: Pleuronectidae) from Denmark.

    PubMed

    Køie, Marianne

    2005-11-01

    A new myxosporean species, Trilosporoides platessae gen. et sp. n. (Multivalvulida), is described from the gallbladder of the plaice Pleuronectes platessa L. (Pleuronectidae) from Denmark. The myxospore of T. platessae is conical in side view, with a 24 microm long, pointed posterior projection. In apical view, the myxospore (diameter 9.4 microm) is round, trilobed and with three spherical polar capsules arranged peripherally, equidistant and opening peripherally through protruding tips. The polar capsules are of different sizes, one often larger than the others (diameter 3.3 microm vs. 2.5 microm). Apart from the long posterior projection, the myxospore of T. platessae differs from those of the three known species of Trilospora Noble, 1959 and from all genera within the order Multivalvulida Shulman, 1959 in the arrangement of the polar capsules. Trilosporoides platessae may temporarily be placed in the vicinity of the Trilosporidae.

  4. Resisting "Reason": A Comparative Anthropological Study of Social Differences and Resistance toward Health Promotion and Illness Prevention in Denmark.

    PubMed

    Merrild, Camilla Hoffmann; Andersen, Rikke Sand; Risør, Mette Bech; Vedsted, Peter

    2016-04-30

    Social differences in health and illness are well documented in Denmark. However, little is known about how health practices are manifested in the everyday lives of different social classes. We propose acts of resistance and formation of health subjectivities as helpful concepts to develop our understanding of how dominant health discourses are appropriated by different social classes and transformed into different practices promoting health and preventing illness. Based on fieldwork in two different social classes, we discuss how these practices both overtly and subtly challenge the normative power of the health promotion discourse. These diverse and ambiguous forms of everyday resistance illustrate how and when situated concerns move social actors to subjectively appropriate health promotion messages. Overall, the different forms of resistance elucidate how the standardized awareness and education campaigns may perpetuate the very inequalities they try to diminish.

  5. Mapping areas at risk of diffuse phosphorus losses to water: a pilot study of Lake Haderslev Dam, Denmark.

    PubMed

    Andersen, Hans Estrup; Heckrath, Goswin; Thodsen, Hans

    2008-01-01

    Haderslev Dam is a 272 ha lake in southern Denmark with a high recreational value. For decades the lake has been severely eutrophicated due to excessive phosphorus loading. Major point sources were cut off in the early 1990s and an upstream wetland was recreated. However, the ecological quality remains unsatisfactory. In this study we estimate the importance of agriculture on diffuse phosphorus (P) input to the lake by modelling combined with independent estimates for contributions from scattered dwellings not connected to a sewer and from background losses. We apply a newly developed Danish P index to the lake catchment for mapping of risk areas for diffuse phosphorus losses. For risk areas we suggest mitigation measures and estimate the effect of the mitigation measures on the total P loading of the lake as well as the associated costs.

  6. Monitoring of equine health in Denmark: the importance, purpose, research areas and content of a future database.

    PubMed

    Hartig, Wendy; Houe, Hans; Andersen, Pia Haubro

    2013-04-01

    The plentiful data on Danish horses are currently neither organized nor easily accessible, impeding register-based epidemiological studies on Danish horses. A common database could be beneficial. In principle, databases can contain a wealth of information, but no single database can serve every purpose. Hence the establishment of a Danish equine health database should be preceded by careful consideration of its purpose and content, and stakeholder attitudes should be investigated. The objectives of the present study were to identify stakeholder attitudes to the importance, purpose, research areas and content of a health database for horses in Denmark. A cross-sectional study was conducted with 13 horse-related stakeholder groups in Denmark. The groups surveyed included equine veterinarians, researchers, veterinary students, representatives from animal welfare organizations, horse owners, trainers, farriers, authority representatives, ordinary citizens, and representatives from laboratories, insurance companies, medical equipment companies and pharmaceutical companies. Supplementary attitudes were inferred from qualitative responses. The overall response rate for all stakeholder groups was 45%. Stakeholder group-specific response rates were 27-80%. Sixty-eight percent of questionnaire respondents thought a national equine health database was important. Most respondents wanted the database to contribute to improved horse health and welfare, to be used for research into durability and disease heritability, and to serve as a basis for health declarations for individual horses. The generally preferred purpose of the database was thus that it should focus on horse health and welfare rather than on performance or food safety, and that it should be able to function both at a population and an individual horse level. In conclusion, there is a positive attitude to the establishment of a health database for Danish horses. These results could enrich further reflection on the

  7. Prenatal exposure to antiepileptic drugs and use of primary healthcare during childhood: a population-based cohort study in Denmark

    PubMed Central

    Würtz, Anne Mette; Vestergaard, Claus Høstrup; Vestergaard, Mogens; Bech, Bodil Hammer

    2017-01-01

    Objective Prenatal exposure to antiepileptic drugs (AEDs) has been associated with adverse outcomes in the offspring such as congenital malformations and neuropsychiatric disorders. The objective of this study was to investigate whether prenatal exposure to AEDs is also associated with more frequent use of primary healthcare during childhood. Design Population-based cohort study. Setting Nationwide national registers in Denmark. Participants All live-born singletons in Denmark during 1997–2012 identified in the Danish National Patient Register and followed until 31 December 2013 (n=963 010). Information on prenatal exposure to AEDs for maternal indication of epilepsy and other neurological conditions was obtained from the Danish Register of Medicinal Product Statistics. Main outcome measures The primary outcome measure was the number and type of contacts with the general practitioner (GP), excluding routine well-child visits and vaccinations. The secondary outcome measure was specific services provided at the GP contact. The association between prenatal exposure to AEDs and contacts with the GP was estimated by using negative binomial regression adjusting for sex and date of birth of the child, maternal age, cohabitation status, income, education, substance abuse, depression, severe psychiatric disorders and use of antipsychotics, antidepressants and insulin. Results Children exposed prenatally to AEDs (n=4478) had 3% (95% CI 0 to 5%) more GP contacts during the study period than unexposed children. This was primarily accounted for by the number of phone contacts. Within each year of follow-up, exposed children tended to have more contacts than unexposed children, but the differences were small. We found no difference between exposed and unexposed children with regard to specific services provided at the GP contact. For the individual AEDs, we found that exposure to valproate or oxcarbazepine was associated with more GP contacts. Conclusions We found only minor

  8. Low hepatitis B prevalence among pre-school children in Denmark: saliva anti-HBc screening in day care centres.

    PubMed

    Fisker, Niels; Georgsen, Jørgen; Stolborg, Torsten; Khalil, Mohammed Rohi; Christensen, Peer Brehm

    2002-12-01

    Although Denmark has a low hepatitis B virus (HBV) prevalence, HBV transmission has been reported in Danish day-care centres. The aim of this study was to validate saliva anti-HBc testing as a method for HBV screening, the applicability of saliva sampling to pre-school children, and to determine the HBV prevalence in Danish day-care centres with a high proportion of immigrants. For validation, paired saliva and plasma samples were obtained from blood donors and injecting drug users. Employees and children in day-care centres with a high proportion of immigrant children were offered saliva screening followed by blood test if positive. The specificity and sensitivity of anti-HBc tests on saliva was 100% (102 blood donors and four injecting drug users) and 85.9% (61 of 71 anti-HBc-positive injecting drug users), respectively. In all samples from HBsAg (n = 7) or anti-HBc IgM-positives (n = 9), anti-HBc was detected in saliva. Adequate saliva samples were obtained from 93% (588/634) of children and 100% (166/166) of employees participating in the day-care centre survey. Among children 55% were of non-Scandinavian origin and only one (0.2%, 95% CI [0.0; 1.0]) was HBV positive. Among employees the corresponding values were 22% and 7 (4.2%). The positive predictive value of the saliva test was 25% (1/4) among children and 88% (7/8) among adults. In conclusion, saliva testing is feasible for HBV screening among children in low prevalence populations, but any anti-HBc reactivity should be confirmed by plasma analysis. The HBV prevalence in pre-school children in Denmark is low even among immigrants from endemic areas.

  9. Enhanced turbulence driven by mesoscale motions and flow-topography interaction in the Denmark Strait Overflow plume

    NASA Astrophysics Data System (ADS)

    Schaffer, Janin; Kanzow, Torsten; Jochumsen, Kerstin; Lackschewitz, Klas; Tippenhauer, Sandra; Zhurbas, Victor M.; Quadfasel, Detlef

    2016-10-01

    The Denmark Strait Overflow (DSO) contributes roughly half to the total volume transport of the Nordic overflows. The overflow increases its volume by entraining ambient water as it descends into the subpolar North Atlantic, feeding into the deep branch of the Atlantic Meridional Overturning Circulation. In June 2012, a multiplatform experiment was carried out in the DSO plume on the continental slope off Greenland (180 km downstream of the sill in Denmark Strait), to observe the variability associated with the entrainment of ambient waters into the DSO plume. In this study, we report on two high-dissipation events captured by an autonomous underwater vehicle (AUV) by horizontal profiling in the interfacial layer between the DSO plume and the ambient water. Strong dissipation of turbulent kinetic energy of O(10-6) W kg-1 was associated with enhanced small-scale temperature variance at wavelengths between 0.05 and 500 m as deduced from a fast-response thermistor. Isotherm displacement slope spectra reveal a wave number-dependence characteristic of turbulence in the inertial-convective subrange (k1/3) at wavelengths between 0.14 and 100 m. The first event captured by the AUV was transient, and occurred near the edge of a bottom-intensified energetic eddy. Our observations imply that both horizontal advection of warm water and vertical mixing of it into the plume are eddy-driven and go hand in hand in entraining ambient water into the DSO plume. The second event was found to be a stationary feature on the upstream side of a topographic elevation located in the plume pathway. Flow-topography interaction is suggested to drive the intense mixing at this site.

  10. Integrating Variable Renewable Energy in Electric Power Markets: Best Practices from International Experience (Fact Sheet)

    SciTech Connect

    Not Available

    2014-10-01

    Many countries--reflecting very different geographies, markets, and power systems--are successfully managing high levels of variable renewable energy (RE) on the grid. Australia (South Australia), Denmark, Germany, Ireland, Spain, and the United States (Colorado and Texas), for example, have effectively integrated variable RE utilizing diverse approaches. Analysis of the results from these case studies reveals a wide range of mechanisms that can be used to accommodate high penetrations of variable RE (e.g., from new market designs to centralized planning). Nevertheless, the myriad approaches collectively suggest that governments can best enable variable RE grid integration by implementing best practices in five areas of intervention: lead public engagement, particularly for new transmission; coordinate and integrate planning; develop rules for market evolution that enable system flexibility; expand access to diverse resources and geographic footprint of operations; and improve system operations.

  11. Palaeoclimatic changes during the Upper Cretaceous of eastern Denmark: a study based on the Stevns-2 chalk core

    NASA Astrophysics Data System (ADS)

    Boussaha, M.; Stemmerik, L.; Thibault, N.

    2013-12-01

    The Stevns-2 core located in eastern Denmark penetrated close to 350 m of upper Campanian-Maastrichtian sediments of the upper Chalk Group (Stemmerik et al., 2006). The calcareous nannofossil biozonation spans the time interval from the UC16aBP from the upper Campanian to the NNT1 in the lowermost Danian. Carbon and Oxygen isotopes trends records climatic events occurring in the upper Cretaceous: (1) the Late Campanian warm climatic optimum, (2) the early Maastrichtian cooling event, (3) the mid-Maastrichtian warming event, and (4) the late Maastrichtian cooling event, also observed in the nearby Stevns-1 core (Thibault et al., 2011) . These climatic variations match closely those observed in the nearby Stevns-1 core and in the Atlantic, Pacific and Tethyan realms (Thibault & GARDIN, 2006; Thibault et al., 2011). Changes occurring in the number of observed Inoceramids prisms per meter of core section, in the abundance of calcareous nannofossils and in the visible trace fossils abundances seem to be linked to climatic changes as expressed in the δ18O of the bulk sediment. In addition to the sedimentological data show that the distribution of facies through time from: (1) cyclic marl alternating with mudstone-wackestone chalk and conglomerates, to (2) bioturbated white mudstone and wackestone chalk, then to (3) flint alternating with mudstone and wackestone chalk, ending with (5) bryozoans wackestone and packstone, and the sedimentation rate changes varying from 1.4 cm/kyr to 13.4 cm/kyr. Here we show how changes in the sedimentology of the chalk and abundances of different fossil group are influenced by global and regional mechanisms. Isotopic results mainly reflect global paleoclimatic changes, whereas the sedimentological record is mostly influenced by (1) local variations in paleoproductivity, (2) deep-water paleocurrents influencing the chalk deposition and the shape of the sea-floor, (3) and (4) the geodynamic activity and paleotopography of the Late

  12. Evaluating Simultaneous Integrals

    ERIC Educational Resources Information Center

    Kwong, Harris

    2012-01-01

    Many integrals require two successive applications of integration by parts. During the process, another integral of similar type is often invoked. We propose a method which can integrate these two integrals simultaneously. All we need is to solve a linear system of equations.

  13. Temporal changes in sugar-sweetened soft drink intake and variation across municipalities in the Capital Region of Denmark.

    PubMed

    Bernsdorf, Kamille Almer; Lau, Cathrine Juel; Robinson, Kirstine; Toft, Ulla; Andreasen, Anne Helms; Glümer, Charlotte

    2016-12-01

    We aimed to examine the changes in sugar-sweetened soft drink intake across the Capital Region of Denmark from 2007 to 2013 and to examine the association between intake and neighbourhood socioeconomic status. The study included data from three health surveys in 2007 (n = 30,426), 2010 (n = 42,218) and 2013 (n = 34,330) in the Capital Region of Denmark. Frequency of soft drink intake was derived from questionnaires among residents aged 25-79 years and linked with information from central registers. Municipality social groups (MSG) 1-4 of decreasing affluence were defined as a composite measure. Logistic regression analyses were conducted for individuals with an appropriate soft drink intake (< once/week) and for individuals with a frequent soft drink intake (≥ 3 times/week). The proportion of individuals reporting an appropriate soft drink intake increased by 71% during 2007-2013 (p < 0.0001). A corresponding decrease was found in the proportion of individuals reporting a frequent soft drink intake. Compared to MSG 1, odds of an appropriate soft drink intake were significantly lower in MSG 3-4: OR = 0.87 (95%CI 0.83-0.91) and OR = 0.89 (95%CI 0.85-0.92), respectively. Compared to MSG 1, odds of a frequent soft drink intake were significantly higher in MSG 3-4: OR = 1.24 (95%CI 1.63-1.31) and 1.17 (95%CI 1.10-1.25), respectively. A significant interaction between MSG and educational level was found among individuals reporting a frequent soft drink intake (p = 0.02). The results show an encouraging reduction in frequency of soft drink intake among capital residents in the period of 2007-2013. A social gradient was observed in soft drink intake across MSG.

  14. Effectiveness of the Gold Standard Programme compared with other smoking cessation interventions in Denmark: a cohort study

    PubMed Central

    Fernández, Esteve; Tønnesen, Hanne

    2017-01-01

    Objectives We compared the effectiveness of the Gold Standard Programme (a comprehensive smoking cessation intervention commonly used in Denmark) with other face-to-face smoking cessation programmes in Denmark after implementation in real life, and we identified factors associated with successful quitting. Design Prospective cohort study. Setting A total of 423 smoking cessation clinics from different settings reported data from 2001 to 2013. Participants In total, 82 515 patients were registered. Smokers ≥15 years old and attending a programme with planned follow-up were included. Smokers who did not want further contact, who intentionally were not followed up or who lacked information about the intervention they received were excluded. A total of 46 287 smokers were included. Interventions Various real-life smoking cessation interventions were identified and compared: The Gold Standard Programme, Come & Quit, crash courses, health promotion counselling (brief intervention) and other interventions. Main outcome Self-reported continuous abstinence for 6 months. Results Overall, 33% (11 184) were continuously abstinent after 6 months; this value was 24% when non-respondents were considered smokers. The follow-up rate was 74%. Women were less likely to remain abstinent, OR 0.83 (CI 0.79 to 0.87). Short interventions were more effective among men. After adjusting for confounders, the Gold Standard Programme was the only intervention with significant results across sex, increasing the odds of abstinence by 69% for men and 31% for women. In particular, compliance, and to a lesser degree, mild smoking, older age and not being disadvantaged were associated with positive outcomes for both sexes. Compliance increased the odds of abstinence more than 3.5-fold. Conclusions Over time, Danish smoking cessation interventions have been effective in real life. Compliance is the main predictor of successful quitting. Interestingly, short programmes seem to have

  15. Framework for combining REACH and national regulations to obtain equal protection levels of human health and the environment in different countries - comparative study of Denmark and Korea.

    PubMed

    Lee, Jihyun; Pedersen, Anders Branth; Pedersen, Anders Brandt; Thomsen, Marianne

    2013-08-15

    The aim of this paper is to present a conceptual framework for a systems approach to protect the environment and human health by taking into account differences in the cumulative risks of total human exposure in a territorial context. To this end the measures that are available and that can be included in REACH exposure scenarios in order to obtain territorially relevant chemical safety assessments (CSAs) were explored. The advantage of linking the REACH exposure scenarios with background environmental quality data reported under other national regulations is discussed. The main question is how REACH may be improved to protect the environment and human health inside and outside the EU. This question is exemplified in a comparative case study of two countries, Denmark and Korea, each with its own set of different environmental qualities and national regulations. As a member of the EU Denmark is obliged to adopt REACH, while Korea implemented REACH to improve the competitiveness of Korean industry within the EU market. It is presented how differences in national regulations and environmental qualities in these two countries affect background human exposure concentrations. Choosing lead as a model compound, the territorial differences in background exposure to endocrine and neurological interfering stressors were modelled. It is concluded that the different territorial soil and air lead pollution levels contribute differently to the total childhood lead exposure in the two countries. As such, the probability of the total exposure from air and soil exceeding 10% of the provisional Total Daily Intake (PTDI) is estimated to be 55.3% in Denmark and 8.2% in Korea. The relative contribution from air inhalation and soil ingestion to childhood lead exposure is estimated to be 1-99% in Denmark while it is 83-17% in Korea.

  16. Childhood exposure to DEHP, DBP and BBP under existing chemical management systems: a comparative study of sources of childhood exposure in Korea and in Denmark.

    PubMed

    Lee, Jihyun; Lee, Jong-Hyeon; Kim, Chan-Kook; Thomsen, Marianne

    2014-02-01

    In this paper, the cumulative risks of Di(2-ethylhexyl) phthalate (DEHP), Di-n-butyl phthalate (DBP), and Benzyl-butyl phthalate (BBP) to 2-year-old children in two countries: one European (Denmark) and one Asian (South Korea) were compared. Denmark does not produce phthalates as a raw material, while Korea produces more than 0.4milliontons of the three above-mentioned phthalates each year. First, a comparative review of the existing phthalate regulations in the two countries was performed. Next, the level of childhood phthalate exposure from environmental and food sources was estimated using an exposure scenario approach. Then, the scenario based exposure level was compared with back-calculated exposure levels based on biomonitored urinary phthalate metabolite concentrations. The result verifies the existence of varying territorial human background exposure levels and the gap between exposure estimations based on exposure modeling and biomonitoring data. Cumulative childhood risk levels in Denmark were lower than in Korea. For both countries, risk levels from back calculation were higher than those from scenario estimation. The median cumulative risk levels from scenario estimation and back calculation respectively were 0.24 and up to 0.5 in Denmark while 0.52 and up to 0.95 in Korea. Food and indoor dust were the main exposure sources for all three phthalates. In order to protect human health from cumulative risks of these phthalates, the exposure scenarios in existing regulations such as the EU REACH need to be strengthened. Moreover, based on the contributions from different exposure sources, national specific risk management tools need to be developed and strengthened, applying a systemic approach to promote sustainable material flows.

  17. Thermionic integrated circuits

    SciTech Connect

    MacRoberts, M.; Brown, D.R.; Dooley, R.; Lemons, R.; Lynn, D.; McCormick, B.; Mombourquette, C.; Sinah, D.

    1986-01-01

    Thermionic integrated circuits combine vacuum-tube technology with integrated-circuit techniques to form integrated vacuum circuits. These circuits are capable of extended operation in both high-temperature and high-radiation environments.

  18. The Modernization of the Energy Sector in Denmark / Modernizacja Sektora Energii W Danii

    NASA Astrophysics Data System (ADS)

    Frączek, Paweł

    2015-03-01

    Denmark is among the leaders who change their energy policy to guarantee its stable and sustainable character. The consistent pursuit of an energy policy enabled the country to lower both the level of its energy consumption and greenhouse gas emissions, while providing grounds for economic development. The study demonstrates that the main factors which led to the transition of Danish energy policy were the oil crisis of the 1970s as well as public expectations regarding their energy policy which was to be based on the concept of stability and sustainability. Dania jest jednym z liderów zmian w polityce energetycznej, zmierzających do stosowania koncepcji rozwoju zrównoważonego i trwałego. W wyniku konsekwentnie realizowanej polityki energetycznej w Danii udało się ograniczyć poziom zużycia energii i emisji gazów cieplarnianych, jednocześnie zapewniając warunki do rozwoju gospodarczego. W opracowaniu wskazano, że głównym czynnikiem, który doprowadził do zmian w polityce energetycznej Danii, był kryzys naftowy lat 70. XX wieku. Przed jego wybuchem dominujący udział w strukturze źródeł energii pierwotnej Danii miała importowana ropa naftowa, która w 1972 r. zaspokajała ponad 90% zapotrzebowania na energię pierwotną w tym kraju. Cechą duńskiego sektora energii była także jego niewielka efektywność oraz wysoki poziom zanieczyszczeń atmosfery związany ze spalaniem paliw kopalnych. Kryzys naftowy wymusił podjęcie działań modernizacyjnych, których celami było m.in. zmniejszenie zużycia energii pierwotnej, zdywersyfikowanie struktury jej źródeł oraz poprawa efektywności sektora energii. Istotnym czynnikiem wymuszającym modernizację duńskiego sektora energii była także kwestia zmiany nastawienia społecznego do prowadzonej polityki energetycznej w Danii. Obecnie w społeczeństwie dominuje pogląd, że podstawą polityki energetycznej powinna być koncepcja rozwoju zrównoważonego i trwa

  19. Micro practices of coordination based on complex adaptive systems: user needs and strategies for coordinating public health in Denmark

    PubMed Central

    Wittrup, Inge; Burau, Viola

    2015-01-01

    Introduction Many highly formalised approaches to coordination poorly fit public health and recent studies call for coordination based on complex adaptive systems. Our contribution is two-fold. Empirically, we focus on public health, and theoretically we build on the patient perspective and treat coordination as a process of contingent, two-level negotiations of user needs. Theory and Methods The paper draws on the concept of user needs-based coordination and sees coordination as a process, whereby needs emerging from the life world of the user are made amenable to the health system through negotiations. The analysis is based on an explorative case study of a health promotion initiative in Denmark. It adopts an anthropological qualitative approach and uses a range of qualitative data. Results The analysis identifies four strategies of coordination: the coordinator focusing on the individual user or on relations with other professionals; and the manager coaching the coordinator or providing structural support. Crucially, the coordination strategies by management remain weak as they do not directly relate to specific user needs. Discussion In process of bottom-up negotiations user needs become blurred and this is especially a challenge for management. The study therefore calls for an increased focus on the level nature of negotiations to bridge the gap that currently weakens coordination strategies by management. PMID:26528097

  20. Storminess variation at Skagen, northern Denmark since AD 1860: Relations to climate change and implications for coastal dunes

    NASA Astrophysics Data System (ADS)

    Clemmensen, Lars B.; Hansen, Kristian W. T.; Kroon, Aart

    2014-12-01

    Systematic observations of wind speed and direction have been collected at Skagen Fyr (Skagen Lighthouse), northern Denmark from December 1860 to August 2012. Wind speed and wind direction are analyzed based on two data sets given in Beaufort and m/s respectively and based on these data storminess variation is analyzed. Changes in wind climate during this time interval cover the final phase of the relatively cold Little Ice Age and the following warming since the late 19th century. Since the end of the Little Ice Age the wind pattern has clearly changed in terms of both strength and direction. Between 1860 and 1875 storminess (wind events exceeding Beaufort 8) is extremely high, but since then storminess decreases. Around 1870 the annual drift potential (DP) is also extremely high and reaches up to 9600 vector units (VU); since 1980 DP levels are below 3000 VU and decreasing. Resultant drift direction (RDD) is towards the east or east-north-east until about 1960 when it steadily becomes more and more northerly. Most storms occur during autumn and early winter. Summers are less stormy but characterized by unidirectional winds. Since the end of the Little Ice Age most inland parabolic dunes on Skagen Odde have undergone a general stabilization. This shift in dune dynamics is primarily related to continued dune management, but the change in wind climate including an overall decrease in storminess (including a marked decrease in summer storminess) and an increase in southerly and south-westerly winds probably contribute to dune stabilization.

  1. Lifelong guidance: How guidance and counselling support lifelong learning in the contrasting contexts of China and Denmark

    NASA Astrophysics Data System (ADS)

    Zhang, Zhixin

    2016-10-01

    Due to the effects of globalisation and rapid technological development, traditional linear life course patterns of the past are gradually disappearing, and this affects education and learning systems as well as labour markets. Individuals are forced to develop lifestyles and survival strategies to manage job insecurity and make their skills and interests meet labour market needs. In modern attempts to develop and implement institutional provision for lifelong learning, guidance and counselling play an important role. The current Danish guidance system is well-organised, highly structured and professionalised. By contrast, Chinese guidance is still fragmented and "sectorisational". This paper explores whether elements of the highly structured and professionalised Danish guidance system and practice might be applicable to the Chinese context. The author begins by outlining international and national factors which are affecting citizens' life and career planning. She then presents and discusses the evolution of guidance and the different elements of provision in each of the two countries. Next, She compares the concepts and goals of "lifelong guidance" in Denmark and China, pointing out their similarities and differences and their respective strengths and weaknesses. The paper concludes with some suggestions for the further development of guidance in China.

  2. Infections with cardiopulmonary and intestinal helminths and sarcoptic mange in red foxes from two different localities in Denmark.

    PubMed

    Al-Sabi, Mohammad N S; Halasa, Tariq; Kapel, Christian M O

    2014-03-01

    Monitoring parasitic infections in the red fox is essential for obtaining baseline knowledge on the spread of diseases of veterinary and medical importance. In this study, screening for cardiopulmonary and intestinal helminths and sarcoptic mange (Sarcoptes scabiei) was done on 118 foxes originating from two distinct localities in Denmark, (Copenhagen) greater area and southern Jutland. Fifteen parasite species were recorded in 116 foxes (98.3%), nine parasitic species are of zoonotic potential. Parasite diversity was greater in foxes of Copenhagen in terms of overall parasite species richness and species richness of all helminth groups individually: trematodes; cestodes; and nematodes. Six parasite species were recovered from foxes of Copenhagen, but not from foxes of Southern Jutland: Echinochasmus perfoliatus; Echinostoma sp.; Pseudamphistomum truncatum; Dipylidium caninum; Angiostrongylus vasorum; and Sarcoptes scabiei, but Toxascaris leonina was only recorded in foxes of southern Jutland. A high prevalence and abundance of A. vasorum in foxes of Copenhagen was observed. The prevalence of four nematode species; Eucoleus (Capillaria) aerophilus, Uncinaria stenocephala, Toxocara canis, and Crenosoma vulpis, in foxes of both localities were comparable and ranging from 22.9% to 89%. The prevalence of Mesocestoides sp. was significantly higher in foxes of Copenhagen. Taenia spp. were detected using morphological and molecular analysis, which revealed the dominance of T. polyacantha in foxes of both localities. Infections with sarcoptic mange were evident only among foxes of Copenhagen (44.9%), which significantly affected the average weight of the infected animals. Further remarks on the zoonotic and veterinary implications of the parasites recovered are given.

  3. Attitudes, knowledge, and proficiency in relation to organ donation: a questionnaire-based analysis in donor hospitals in northern Denmark.

    PubMed

    Bøgh, L; Madsen, M

    2005-10-01

    The aim of this study was to assess knowledge, attitudes, and proficiency in relation to organ donation among staff members of intensive care units (ICUs) in donor hospitals, and possibly identify areas for improvement. The investigation was carried out as a collaboration between the transplant center and appointed key persons in all 17 ICUs in 15 hospitals in northern Denmark. A total of 1168 structured questionnaires were distributed to the health care professionals in the ICUs in the region; 689 were returned, giving a response rate of 59%. In general, there is a positive attitude among health care professionals toward organ donation. However, a considerable fraction of 11% declares to be against organ donation. Only 49% of the ICU health care professionals are willing to donate their own organs after death. By comparison, 74% of the general Danish population are willing to donate organs after death. Doctors are more positive toward organ donation than the nursing staff. Thus, 95% of the doctors are positive to organ donation compared to 81% of the nurses; 70% of the doctors will donate own organs after death compared to 45% of the nurses. Further, the survey demonstrates as expected a significant lack of experience in organ donation. Our data show a considerable need for more education and training, especially on how to inform and support the donor relatives and how to identify potential donors. The survey also discloses a substantial need for information regarding the results of transplantation.

  4. Does Moralization Motivate Smokers to Quit? A Longitudinal Study of Representative Samples of Smokers in the United States and Denmark

    PubMed Central

    2014-01-01

    Introduction: Moralization refers to the gradual cultural and personal process by which objects or activities move from being morally neutral to morally contemptuous. Research suggests important cross-cultural differences in how smokers react to being targets of moralization. However, research has not examined whether smokers who agree with moralized sentiments about smoking are more willing to quit or reduce their smoking. Additionally, the mediating role of perceived personal risk has not been examined. Methods: In this study, representative samples of smokers in Denmark (a smoking lenient country; N = 429) and the United States (a smoking prohibitive country; N = 431) completed surveys 6 months apart. Results: As expected, Danish smokers (compared to U.S. smokers) moralized less and estimated that their personal risk of lung cancer was smaller. Furthermore, moralization at T1 predicted an increase in perceived personal risk at T2 (for Danish smokers and marginally for U.S. smokers), a decrease in smoking behaviors (for Danish smokers only), and an increase in quitting intentions (marginally for Danish smokers only). For Danish smokers, perceived personal risk mediated the relationship between moralization and quitting intentions. Conclusions: Moralization predicted an increase in perceived personal risk, an increase in quitting intentions, and a reduction in smoking behaviors, especially for the Danish sample. Future research should examine the effects of moralization in different cultural contexts. PMID:24907242

  5. The attribution of human infections with antimicrobial resistant Salmonella bacteria in Denmark to sources of animal origin.

    PubMed

    Hald, Tine; Lo Fo Wong, Danilo M A; Aarestrup, Frank M

    2007-01-01

    Based on the Danish Salmonella surveillance in 2000-2001, we developed a mathematical model for quantifying the contribution of each major animal-food sources to human salmonellosis caused by antimicrobial resistant bacteria. Domestic food products accounted for 53.1% of all cases, mainly caused by table eggs (37.6%). A large proportion (19%) of cases were travel related, while 18% could not be associated with any source. Imported food products accounted for 9.5% of all cases; the most important source being imported chicken. Multidrug and quinolone resistance was rarely found in cases acquired from Danish food, but was common in cases related to imported products (49.7% and 35.6% of attributable cases) and travelling (26.5% and 38.3% of attributable cases). For most serovars, the quinolone-resistant isolates were found to be associated with relatively more human infections than that of resistant isolates, which in turn was higher than that of susceptible isolates. This may be due to quinolone-resistant isolates having a higher ability to survive food processing and/or cause disease. This study showed domestic food to be the most important source of Salmonella infections in Denmark, but infections with multidrug- and quinolone-resistant isolates were more commonly caused by imported food products and travelling, emphasizing the need for a global perspective on food safety and antimicrobial usage.

  6. Food on foot: long-distance trade in slaughter oxen between Denmark and the Netherlands (14th-18th century).

    PubMed

    Gijsbers, W; Koolmees, P

    2001-01-01

    This paper presents a short review of the long-distance trade in slaughter oxen in Northwest Europe. The long-term development of the trade is described against the social-economic background of the production and consumption areas. In the 14th century, the Danes obtained the right to sell cattle in certain Dutch cities. From 1500 onwards, the export of oxen from Denmark and the adjacent duchy of Schleswig-Holstein increased considerably. The export reached its peak in the first quarter of the 17th century; registered export in 1612 amounted to more than 52.000 oxen over land and, in 1624, about 10.000 oxen over sea. Part of that export was destined for the Dutch market. Protectionist tax measures taken by the Dutch government and the outbreaks of rinderpest put an end to the regular ox trade in the first half of the 18th century. By decree, local authorities tried to prevent the spread of contagious animal diseases. The history of international cattle trade and hauling, however, indicates that economic motives largely outweighed animal welfare issues. Thus, in addition to addressing the logistics of the trade, this paper also addresses veterinary aspects and animal welfare issues related to the transport of cattle.

  7. Material flow analysis of NdFeB magnets for Denmark: a comprehensive waste flow sampling and analysis approach.

    PubMed

    Habib, Komal; Schibye, Peter Klausen; Vestbø, Andreas Peter; Dall, Ole; Wenzel, Henrik

    2014-10-21

    Neodymium-iron-boron (NdFeB) magnets have become highly desirable for modern hi-tech applications. These magnets, in general, contain two key rare earth elements (REEs), i.e., neodymium (Nd) and dysprosium (Dy), which are responsible for the very high strength of these magnets, allowing for considerable size and weight reduction in modern applications. This study aims to explore the current and future potential of a secondary supply of neodymium and dysprosium from recycling of NdFeB magnets. For this purpose, material flow analysis (MFA) has been carried out to perform the detailed mapping of stocks and flows of NdFeB magnets in Denmark. A novel element of this study is the value added to the traditionally practiced MFAs at national and/or global levels by complementing them with a comprehensive sampling and elemental analysis of NdFeB magnets, taken out from a sample of 157 different products representing 18 various product types. The results show that the current amount of neodymium and dysprosium in NdFeB magnets present in the Danish waste stream is only 3 and 0.2 Mg, respectively. However, this number is estimated to increase to 175 Mg of neodymium and 11.4 Mg of dysprosium by 2035. Nevertheless, efficient recovery of these elements from a very diverse electronic waste stream remains a logistic and economic challenge.

  8. Negative effects of blue mussel ( Mytilus edulis) presence in eelgrass ( Zostera marina) beds in Flensborg fjord, Denmark

    NASA Astrophysics Data System (ADS)

    Vinther, Hanne Fogh; Laursen, Jens Sund; Holmer, Marianne

    2008-03-01

    The effect of blue mussel ( Mytilus edulis) presence in eelgrass ( Zostera marina) beds was studied from June 2004 to July 2005 in Flensborg fjord, Denmark. The field experiments were conducted at two stations, one with only Z. marina (Eelgrass station) present and one where M. edulis were present in the Z. marina beds (Mixed station). Zostera marina parameters were measured (growth of leaves, shoot density, leaf length, and nutrient content) in combination with epiphyte cover and sediment parameters (sulphate reduction rates, sediment nutrient fluxes, organic content, C, N and P content) to examine possible positive and negative effects of the mussels on eelgrass performance. The fluxes of ammonium from the sediments were stimulated at all sampling dates at the Mixed station, and possibly stimulated epiphyte growth at this station. Further 15N signals in epiphytes from the Mixed station suggested that excretion products from the mussels were important nitrogen sources at this station. Sulphate reduction rates were enhanced at the Mixed station and also sediment sulphide concentrations increased under mussel influence, which may have resulted in sulphide toxicity and decreased growth of Z. marina at this station. The study indicates that for Z. marina beds in Flensborg Fjord the effects of M. edulis in seagrass beds are primarily negative, and raises the question whether this leads to negative effects on the stability and expansion of Z. marina beds.

  9. Physico-chemical characterisation of material fractions in residual and source-segregated household waste in Denmark.

    PubMed

    Götze, R; Pivnenko, K; Boldrin, A; Scheutz, C; Astrup, T Fruergaard

    2016-08-01

    Physico-chemical waste composition data are paramount for the assessment and planning of waste management systems. However, the applicability of data is limited by the regional, temporal and technical scope of waste characterisation studies. As Danish and European legislation aims for higher recycling rates evaluation of source-segregation and recycling chains gain importance. This paper provides a consistent up-to-date dataset for 74 physico-chemical parameters in 49 material fractions from residual and 24 material fractions from source-segregated Danish household waste. Significant differences in the physico-chemical properties of residual and source-segregated waste fractions were found for many parameters related to organic matter, but also for elements of environmental concern. Considerable differences in potentially toxic metal concentrations between the individual recyclable fractions within one material type were observed. This indicates that careful planning and performance evaluation of recycling schemes are important to ensure a high quality of collected recyclables. Rare earth elements (REE) were quantified in all waste fractions analysed, with the highest concentrations of REE found in fractions with high content of mineral raw materials, soil materials and dust. The observed REE concentrations represent the background concentration level in non-hazardous waste materials that may serve as a reference point for future investigations related to hazardous waste management. The detailed dataset provided here can be used for assessments of waste management solutions in Denmark and for the evaluation of the quality of recyclable materials in waste.

  10. Separate norovirus outbreaks linked to one source of imported frozen raspberries by molecular analysis, Denmark, 2010-2011.

    PubMed

    Müller, L; Schultz, A C; Fonager, J; Jensen, T; Lisby, M; Hindsdal, K; Krusell, L; Eshøj, A; Møller, L T; Porsbo, L J; Böttiger, B E; Kuhn, K; Engberg, J; Ethelberg, S

    2015-08-01

    Norovirus outbreaks occur frequently in Denmark and it can be difficult to establish whether apparently independent outbreaks have the same origin. Here we report on six outbreaks linked to frozen raspberries, investigated separately over a period of 3 months. Norovirus from stools were sequence-typed; including extended sequencing of 1138 bp encompassing the hypervariable P2 region of the capsid gene. Norovirus was detected in 27 stool samples. Genotyping showed genotype GI.Pb_GI.6 (polymerase/capsid) with 100% identical sequences. Samples from five outbreaks were furthermore identical over the variable capsid P2 region. In one outbreak at a hospital canteen, frozen raspberries was associated with illness by cohort investigation (relative risk 6·1, 95% confidence interval 3·2-11). Bags of raspberries suspected to be the source were positive for genogroup I and II noroviruses, one typable virus was genotype GI.6 (capsid). These molecular investigations showed that the apparently independent outbreaks were the result of one contamination event of frozen raspberries. The contaminated raspberries originated from a single producer in Serbia and were originally not considered to belong to the same batch. The outbreaks led to consultations and mutual visits between producers, investigators and authorities. Further, Danish legislation was changed to make heat-treatment of frozen raspberries compulsory in professional catering establishments.

  11. Risk of neurological diseases among survivors of electric shocks: a nationwide cohort study, Denmark, 1968-2008.

    PubMed

    Grell, Kathrine; Meersohn, Andrea; Schüz, Joachim; Johansen, Christoffer

    2012-09-01

    Several studies suggest a link between electric injuries and neurological diseases, where electric shocks may explain elevated risks for neuronal degeneration and, subsequently, neurological diseases. We conducted a retrospective cohort study on the risk of neurological diseases among people in Denmark who had survived an electric accident in 1968-2008. The cohort included 3,133 people and occurrences of neurological diseases were determined by linkage to the nationwide population-based Danish National Register of Patients. The numbers of cases observed at first hospital contact in the cohort were compared with the respective rates of first hospital contacts for neurological diseases in the general population. We observed significantly increased risks for peripheral nerve diseases (standardized hospitalization ratio (SHR), 1.66; 95% confidence interval (CI), 1.22-2.22), for migraine (SHR, 1.80; 95% CI, 1.23-2.54), for vertigo (SHR, 1.60; 95% CI, 1.22-2.05), and for epilepsy (SHR, 1.45; 95% CI, 1.11-1.85). Only small numbers of cases of other neurological diseases were found, making the risk estimates unstable. These findings suggest an association between a single electric shock and increased risks for peripheral nerve diseases, migraines, vertigo, and epilepsy, but confirmation of these observations is needed.

  12. Forensic aspects of carbon monoxide poisoning by charcoal burning in Denmark, 2008-2012: an autopsy based study.

    PubMed

    Nielsen, Pia Rude; Gheorghe, Alexandra; Lynnerup, Niels

    2014-09-01

    Carbon monoxide (CO) inhalation is a well-known method of committing suicide. There has been a drastic increase in suicide by inhalation of CO, produced from burning charcoal, in some parts of Asia, and a few studies have reported an increased number of these deaths in Europe. CO-related deaths caused by charcoal burning have, to our knowledge, not been recorded in the Danish population before. In this retrospective study we present all autopsied cases of CO poisoning caused by charcoal burning in the period 2008-2012. 19 autopsied cases were identified, comprising 11 suicides, 4 accidents, and 2 cases of maternal/paternal filicide-suicide. The mean age of decedents was 38.2 years and the majority of the decedents were men. In 16 cases carboxyhemoglobin levels were above 50 % and in 14 cases we found distinctive cherry red livor mortis. Various concentrations of ethanol and drugs were found in 9 cases. Data suggest that this method of death has increased significantly in Denmark. Therefore, it is highly relevant to draw attention to the subject, to increase awareness as well as prevent future escalation.

  13. High precision {sup 230}Th and {sup 232}Th in the Norwegian Sea and Denmark by thermal ionization mass spectrometry

    SciTech Connect

    Moran, S.B.; Hoff, J.A.; Edwards, R.L.

    1995-10-01

    Seawater samples (1-2 liters) were collected from the Norwegian Sea and Denmark Strait and analyzed for {sup 230}Th and {sup 232}Th using highly sensitive thermal ionization mass spectrometry (TIMS). Depth profiles of dissolved {sup 230}Th and {sup 232}Th are characterized by surface water minima (<1 fg/kg, <5 pg/kg), subsurface maxima (12 fg/kg, 134 pg/kg), and intermediate concentrations that progressively decrease toward the bottom ({approximately}5 fg/kg, {approximately}17 pg/kg), respectively. The lack of an increase in {sup 230}Th with depth is suggested to result from the short ventilation age of Norwegian Sea Deep Water combined with enhanced scavenging near the basin margins. The {sup 230}Th maximum is attributed to advection of high {sup 230}Th in the Arctic Intermediate Water, whereas the {sup 232}Th maximum may he related to a particulate source. The low dissolved {sup 230}Th and {sup 232}Th concentrations observed in the NADW formation regions implies a minor advective export of these long-lived Th tracers to the North Atlantic. 24 refs., 1 fig., 1 tab.

  14. The introduction of sialendoscopy has significantly contributed to a decreased number of excised salivary glands in Denmark.

    PubMed

    Rasmussen, Eva Rye; Lykke, Eva; Wagner, Niels; Nielsen, Troels; Waersted, Stian; Arndal, Helge

    2016-08-01

    Excision has been the treatment of choice in benign non-tumorous obstructive disorders of the major salivary glands, when symptoms persisted in spite of conservative measures. Unfortunately surgical resection has been associated with a relatively high rate of adverse effects. To meet the need for a less invasive treatment modality for benign obstructive non-tumorous disorders (i.e., salivary stones or stenosis), sialendoscopy has been developed and implemented in several countries here among Denmark. This study is a 13-year retrospective registry-based study using The Danish National Patient Register. ICD-10 codes used for non-tumorous obstructive disease of the salivary glands were identified and used to extract patients potentially eligible for sialendoscopy in order to compare sialendoscopic surgery and extirpations of salivary glands. In 2012 sialendoscopy accounted for almost 20 % of all surgical interventions on the major salivary glands due to benign non-tumorous disease. Nationally and regionally the total number of resected major salivary glands due to benign obstructive disease also decreased significantly during the study period. A positive outcome, like the ones described here, will inspire further development and dissemination of gland preserving techniques, to great benefit for the patients.

  15. Laboratory surveillance of urogenital Chlamydia trachomatis infections in Denmark 1988-2007.

    PubMed

    Lind, Inga; Bollerup, Anne Cathrine; Farholt, Stense; Hoffmann, Steen

    2009-01-01

    In 1994 laboratory reporting of urogenital chlamydia was integrated in the countrywide notification system for infectious diseases. Previously (1988-1993), laboratory confirmed cases had been reported on a voluntary basis. The applied laboratory technologies changed significantly: in 1988, 48% of cases were diagnosed by culture; in 1994, 88% by enzyme immunoassays; and since 2004 more than 99% by nucleic acid amplification tests. The proportions of chlamydia-positive men diagnosed by testing urine were <1% in 1994, 10% in 2001 and 75% in 2007. From 1994 to 2002 the annual incidence rates of chlamydia per 100,000 population among women were around 350-400 and then increased to 586 in 2007. Among men the incidence rate rose from 125 in 1994 to 358 in 2007. In conclusion, the annual incidence rates of urogenital chlamydia remained high and possibly increasing during a 14-y period (1994-2007), with a high testing activity, improving technologies and countrywide information campaigns. The observed increase is likely to be associated with the introduction of more sensitive diagnostic methods and with increasing testing of men. A possible change in target groups from low- to high-prevalence could not be assessed due to lack of information about persons being tested.

  16. Parents’ socioeconomic factors related to high antibiotic prescribing in primary health care among children aged 0–6 years in the Capital Region of Denmark

    PubMed Central

    Jensen, Jette Nygaard; Bjerrum, Lars; Boel, Jonas; Jarløv, Jens Otto; Arpi, Magnus

    2016-01-01

    Objective To investigate the distribution of antibiotic prescriptions in primary health care among children aged 0–6 years and its association with socioeconomic factors. Design A cross-sectional study describing antibiotic prescriptions and socioeconomic factors, using different population-based registers from Statistics Denmark. Setting Antibiotic prescriptions in 2012 from primary health care in the Capital Region of Denmark. Subjects The population of children aged 0–6 years (n = 139,398) in the Capital Region of Denmark. Main outcome measures High use of antibiotics identified by number of antibiotic prescriptions (≥ 3 prescriptions per year) and defined daily doses (DDD). A multinomial logistic regression analysis estimating the association between high antibiotic use and parents’ education, employment status, income, child’s sex, and ethnic background. Results Ten percent of children accounted for 25% of the total use DDD. There was a clear tendency that the risk for high antibiotic use increased as parental educational level decreased. The risk for high use was the highest among children of mothers and fathers with basic schooling ≤10 years (OR 1.60, 95% CI 1.29–1.98, and OR 1.60, 95% CI 1.34–1.91, respectively). Low income and unemployment were not associated with high antibiotic use. Conclusion Socioeconomic factors can only partially explain differences in antibiotic use. Further research is needed to clarify the unequal distribution of antibiotic prescribing and the association between high antibiotic use and low educational level. This would provide valuable information in the planning of strategies to promote rational use of antibiotics among children. Key Points The Capital Region of Denmark has the highest rate of antibiotic prescribing in Denmark.Preschool children are among the age groups with the highest use.Ten percent of the children accounted for 25% of the total antibiotic use.Low parental educational level was

  17. Association between Integration Policies and Immigrants’ Mortality: An Explorative Study across Three European Countries

    PubMed Central

    Ikram, Umar Z.; Malmusi, Davide; Juel, Knud; Rey, Grégoire; Kunst, Anton E.

    2015-01-01

    Background To integrate immigrants into their societies, European countries have adopted different types of policies, which may influence health through both material and psychosocial determinants. Recent studies have suggested poorer health outcomes for immigrants living in countries with poorly rated integration policies. Objective To analyse mortality differences of immigrants from the same country of origin living in countries with distinct integration policy contexts. Methods From the mortality dataset collected in the Migrant Ethnic Health Observatory (MEHO) project, we chose the Netherlands (linked data from 1996-2006), France (unlinked; 2005-2007) and Denmark (linked; 1992-2001) as representatives of the inclusive, assimilationist and exclusionist policy models, respectively, based on the Migrant Integration Policy Index. We calculated for each country sex- and age-standardized mortality rates for Turkish-, Moroccan- and local-born populations aged 20-69 years. Poisson regression was used to estimate the mortality rate ratios (MRRs) for cross-country and within-country comparisons. The analyses were further stratified by age group and cause of death. Results Compared with their peers in the Netherlands, Turkish-born immigrants had higher all-cause mortality in Denmark (MRR men 1.92; 95% CI 1.74-2.13 and women 2.11; 1.80-2.47) but lower in France (men 0.64; 0.59-0.69 and women 0.58; 0.51-0.67). A similar pattern emerged for Moroccan-born immigrants. The relative differences between immigrants and the local-born population were also largest in Denmark and lowest in France (e.g., Turkish-born men MRR 1.52; 95% CI 1.38-1.67 and 0.62; 0.58-0.66, respectively). These patterns were consistent across all age groups, and more marked for cardiovascular diseases. Conclusions Although confounders and data comparability issues (e.g., French cross-sectional data) may affect the findings, this study suggests that different macro-level policy contexts may influence

  18. Relations Between Hyperelliptic Integrals

    NASA Astrophysics Data System (ADS)

    Pakuliak, S.; Perelomov, A.

    A simple property of the integrals over the hyperelliptic surfaces of arbitrary genus is observed. Namely, the derivatives of these integrals with respect to the branching points are given by the linear combination of the same integrals. We check that this property is responsible for the solution to the level zero Knizhnik-Zamolodchikov equation given in terms of hyperelliptic integrals.

  19. Slimplectic Integrators: Variational Integrators for Nonconservative systems

    NASA Astrophysics Data System (ADS)

    Tsang, David

    2016-05-01

    Symplectic integrators are widely used for long-term integration of conservative astrophysical problems due to their ability to preserve the constants of motion; however, they cannot in general be applied in the presence of nonconservative interactions. Here we present the “slimplectic” integrator, a new type of numerical integrator that shares many of the benefits of traditional symplectic integrators yet is applicable to general nonconservative systems. We utilize a fixed-time-step variational integrator formalism applied to a newly developed principle of stationary nonconservative action (Galley, 2013, Galley et al 2014). As a result, the generalized momenta and energy (Noether current) evolutions are well-tracked. We discuss several example systems, including damped harmonic oscillators, Poynting-Robertson drag, and gravitational radiation reaction, by utilizing our new publicly available code to demonstrate the slimplectic integrator algorithm. Slimplectic integrators are well-suited for integrations of systems where nonconservative effects play an important role in the long-term dynamical evolution. As such they are particularly appropriate for cosmological or celestial N-body dynamics problems where nonconservative interactions, e.g., gas interactions or dissipative tides, can play an important role.

  20. Groundwater modeling in integrated water resources management--visions for 2020.

    PubMed

    Refsgaard, Jens Christian; Højberg, Anker Lajer; Møller, Ingelise; Hansen, Martin; Søndergaard, Verner

    2010-01-01

    Groundwater modeling is undergoing a change from traditional stand-alone studies toward being an integrated part of holistic water resources management procedures. This is illustrated by the development in Denmark, where comprehensive national databases for geologic borehole data, groundwater-related geophysical data, geologic models, as well as a national groundwater-surface water model have been established and integrated to support water management. This has enhanced the benefits of using groundwater models. Based on insight gained from this Danish experience, a scientifically realistic scenario for the use of groundwater modeling in 2020 has been developed, in which groundwater models will be a part of sophisticated databases and modeling systems. The databases and numerical models will be seamlessly integrated, and the tasks of monitoring and modeling will be merged. Numerical models for atmospheric, surface water, and groundwater processes will be coupled in one integrated modeling system that can operate at a wide range of spatial scales. Furthermore, the management systems will be constructed with a focus on building credibility of model and data use among all stakeholders and on facilitating a learning process whereby data and models, as well as stakeholders' understanding of the system, are updated to currently available information. The key scientific challenges for achieving this are (1) developing new methodologies for integration of statistical and qualitative uncertainty; (2) mapping geological heterogeneity and developing scaling methodologies; (3) developing coupled model codes; and (4) developing integrated information systems, including quality assurance and uncertainty information that facilitate active stakeholder involvement and learning.

  1. A hindcast and forecast of management of agricultural nutrient losses in Denmark: a change in paradigm (Invited)

    NASA Astrophysics Data System (ADS)

    kronvang, B.; Blicher-Mathiesen, G.; Windolf, J.; Grant, R.

    2013-12-01

    Four major Action Plans on the Aquatic Environment have been implemented in Denmark since 1987 with the aim to reduce by 50% the nitrogen (N) loading and by 80% the phosphorus (P) loading to the aquatic environment. At the same time the Danish National Aquatic Monitoring and Assessment Programme (NOVA) was launched with the aim to follow the effects of the obligatory implemented management strategies in Danish agriculture. Monitoring of the effects took place in 5 small agricultural catchments in soil water, groundwater and surface waters with annual interviews of farmers practices at field level as well as a general monitoring of nutrient concentrations in groundwater, streams, rivers, lakes and estuaries all over Denmark. Considerable changes in agricultural practice (storage of slurry, ban on slurry spreading in autumn and winter, strict requirements to N-use in animal manure, N-norms to all crops to be fixed to 10% below economic optimum, etc.) have resulted in a reduction of the net N-surplus from 136 to 75 kg N ha-1 yr-1 (45%) and the net P-surplus from 19 to around 0 kg P ha-1 yr-1 (100%) during the period 1985-2011..Twenty-five years of experience gathered from NOVA have shown that the losses of total N (TN) and total P (TP) to the marine environment from both point sources and diffuse sources has decreased with 50% and 50%, respectively. The reduction in TN losses alone amounts to 40%, whereas no general reduction in TP from diffuse losses can be detected. Despite the great efforts in improving the management of N and P in Danish agriculture the sector is today still the major source of both N (80%) and P (50%) in Danish streams, lakes and coastal waters. The ecological conditions in Danish streams, lakes and estuaries are still below the at least good ecological quality required by the EU Water Framework Directive adopted in year 2000. As global demand for food is increasing the Danish Government last year initiated a commission to publish a white book on

  2. Liquid freshwater transport estimates from the East Greenland Current based on continuous measurements north of Denmark Strait

    NASA Astrophysics Data System (ADS)

    de Steur, L.; Pickart, R. S.; Macrander, A.; Vâge, K.; Harden, B.; Jónsson, S.; Østerhus, S.; Valdimarsson, H.

    2017-01-01

    Liquid freshwater transports of the shelfbreak East Greenland Current (EGC) and the separated EGC are determined from mooring records from the Kögur section north of Denmark Strait between August 2011 and July 2012. The 11 month mean freshwater transport (FWT), relative to a salinity of 34.8, was 65 ± 11 mSv to the south. Approximately 70% of this was associated with the shelfbreak EGC and the remaining 30% with the separated EGC. Very large southward FWT ranging from 160 mSv to 120 mSv was observed from September to mid-October 2011 and was foremost due to anomalously low upper-layer salinities. The FWT may, however, be underestimated by approximately 5 mSv due to sampling biases in the upper ocean. The FWT on the Greenland shelf was estimated using additional inshore moorings deployed from 2012 to 2014. While the annual mean ranged from nearly zero during the first year to 18 mSv to the south during the second year, synoptically the FWT on the shelf can be significant. Furthermore, an anomalous event in autumn 2011 caused the shelfbreak EGC to reverse, leading to a large reduction in FWT. This reversed circulation was due to the passage of a large, 100 km wide anticyclone originating upstream from the shelfbreak. The late summer FWT of -131 mSv is 150% larger than earlier estimates based on sections in the late-1990s and early-2000s. This increase is likely the result of enhanced freshwater flux from the Arctic Ocean to the Nordic Seas during the early 2010s.

  3. Advanced paternal age and stillbirth rate: a nationwide register-based cohort study of 944,031 pregnancies in Denmark.

    PubMed

    Urhoj, Stine Kjaer; Andersen, Per Kragh; Mortensen, Laust Hvas; Davey Smith, George; Nybo Andersen, Anne-Marie

    2017-03-01

    Advanced paternal age has been associated with a variety of rare conditions and diseases of great public health impact. An increased number of de novo point mutations in sperm with increasing age have been suggested as a mechanism, which would likely also affect fetal viability. We examined the association between paternal age and stillbirth rate in a large nationwide cohort. We identified all pregnancies in Denmark from 1994 to 2010 carried to a gestational age of at least 22 completed weeks (n = 944,031) as registered in national registers and linked to individual register data about the parents. The hazard ratio of stillbirth according to paternal age was estimated, adjusted for maternal age in 1-year categories, year of outcome, and additionally parental educational levels. The relative rate of stillbirth (n = 4946) according to paternal age was found to be J-shaped with the highest hazard ratio for fathers aged more than 40 years when paternal age was modelled using restricted cubic splines. When modelled categorically, the adjusted hazard ratios of stillbirth were as follows: <25, 1.16 (95% confidence interval, CI 1.01-1.34); 25-29, 1.03 (95% CI 0.95-1.11); 35-39, 1.16 (95% CI 1.07-1.26); 40-44, 1.41 (95% CI 1.26-1.59); 45-49, 1.20 (95% CI 0.97-1.49); 50+, 1.58 (95% CI 1.18-2.11), compared with fathers aged 30-34 years. These estimates attenuated slightly when further adjusted for parental education. Our study showed that paternal age was associated with the relative rate of stillbirth in a J-shaped manner with the highest hazard ratios among fathers aged more than 40 years.

  4. Implementation of interval walking training in patients with type 2 diabetes in Denmark: rationale, design, and baseline characteristics

    PubMed Central

    Ried-Larsen, Mathias; Thomsen, Reimar W; Berencsi, Klara; Brinkløv, Cecilie F; Brøns, Charlotte; Valentiner, Laura S; Karstoft, Kristian; Langberg, Henning; Vaag, Allan A; Pedersen, Bente K; Nielsen, Jens S

    2016-01-01

    Promoting physical activity is a first-line choice of treatment for patients with type 2 diabetes (T2D). However, there is a need for more effective tools and technologies to facilitate structured lifestyle interventions and to ensure a better compliance, sustainability, and health benefits of exercise training in patients with T2D. The InterWalk initiative and its innovative application (app) for smartphones described in this study were developed by the Danish Centre for Strategic Research in T2D aiming at implementing, testing, and validating interval walking in patients with T2D in Denmark. The interval walking training approach consists of repetitive 3-minute cycles of slow and fast walking with simultaneous intensity guiding, based on the exercise capacity of the user. The individual intensity during slow and fast walking is determined by a short initial self-conducted and audio-guided fitness test, which combined with automated audio instructions strives to motivate the individual to adjust the intensity to the predetermined individualized walking intensities. The InterWalk app data are collected prospectively from all users and will be linked to the unique Danish nationwide databases and administrative registries, allowing extensive epidemiological studies of exercise in patients with T2D, such as the level of adherence to InterWalk training and long-term effectiveness surveys of important health outcomes, including cardiovascular morbidity and mortality. Currently, the InterWalk app has been downloaded by >30,000 persons, and the achieved epidemiological data quality is encouraging. Of the 9,466 persons providing personal information, 80% of the men and 62% women were overweight or obese (body mass index ≥25). The InterWalk project represents a contemporary technology-driven public health approach to monitor real-life exercise adherence and to propagate improved health through exercise intervention in T2D and in the general population. PMID:27354828

  5. Heavy lifting at work and risk of retinal detachment: a population-based register study in Denmark

    PubMed Central

    Curti, Stefania; Coggon, David; Hannerz, Harald; Mattioli, Stefano

    2016-01-01

    Objectives To investigate the relationship between rhegmatogenous retinal detachment (RRD) and frequent heavy lifting in a Danish working population through national register data. Methods A dynamic cohort of all men aged 20–59 years in Denmark was followed through the Danish Occupational Hospitalisation Register from 1995 to 2010 for diagnosed RRD. Occupational categories were classified according to their potential for heavy lifting in 4 main groups: heavy lifters, manual workers unlikely to be heavy lifters, other manual workers and non-manual workers unlikely to be heavy lifters. The age-standardised rate of diagnosed RRD for heavy lifting occupations was compared with that experienced by the other 3 occupational categories. Rate ratios (RRs) and 95% CIs were estimated through a Poisson regression model adjusted for calendar period and age group. Results The highest age-standardised rate of diagnosed RRD was recorded among non-manual workers performing occupational activities unlikely to be associated with heavy lifting (18.0 cases per 100 000 person-years). The RR for workers in jobs expected to entail a high frequency of heavy lifting compared with manual workers whose occupation was unlikely to be associated with heavy lifting was 0.91 (95% CI 0.73 to 1.14), while in comparison with other manual workers, it was 0.93 (95% CI 0.78 to 1.11). The RR compared with non-manual workers in occupations unlikely to entail heavy lifting was 0.51 (95% CI 0.43 to 0.60). Conclusions These findings do not support an association of occupational heavy lifting with diagnosed RRD. The epidemiological evidence for this association is still inconclusive. Future studies should use a more specific measure of exposure to resolve the outstanding uncertainties. PMID:26561504

  6. Gastrointestinal Illness among Triathletes Swimming in Non-Polluted versus Polluted Seawater Affected by Heavy Rainfall, Denmark, 2010-2011

    PubMed Central

    Harder-Lauridsen, Nina Majlund; Kuhn, Katrin Gaardbo; Erichsen, Anders Christian; Mølbak, Kåre; Ethelberg, Steen

    2013-01-01

    Recent years have seen an increase in the frequency of extreme rainfall and subsequent flooding across the world. Climate change models predict that such flooding will become more common, triggering sewer overflows, potentially with increased risks to human health. In August 2010, a triathlon sports competition was held in Copenhagen, Denmark, shortly after an extreme rainfall. The authors took advantage of this event to investigate disease risks in two comparable cohorts of physically fit, long distance swimmers competing in the sea next to a large urban area. An established model of bacterial concentration in the water was used to examine the level of pollution in a spatio-temporal manner. Symptoms and exposures among athletes were examined with a questionnaire using a retrospective cohort design and the questionnaire investigation was repeated after a triathlon competition held in non-polluted seawater in 2011. Diagnostic information was collected from microbiological laboratories. The results showed that the 3.8 kilometer open water swimming competition coincided with the peak of post-flooding bacterial contamination in 2010, with average concentrations of 1.5x104 E. coli per 100 ml water. The attack rate of disease among 838 swimmers in 2010 was 42% compared to 8% among 931 swimmers in the 2011 competition (relative risk (RR) 5.0; 95% CI: 4.0-6.39). In 2010, illness was associated with having unintentionally swallowed contaminated water (RR 2.5; 95% CI: 1.8-3.4); and the risk increased with the number of mouthfuls of water swallowed. Confirmed aetiologies of infection included Campylobacter, Giardia lamblia and diarrhoeagenic E. coli. The study demonstrated a considerable risk of illness from water intake when swimming in contaminated seawater in 2010, and a small but measureable risk from non-polluted water in 2011. This suggests a significant risk of disease in people ingesting small amounts of flood water following extreme rainfall in urban areas. PMID

  7. Substance flow analysis of parabens in Denmark complemented with a survey of presence and frequency in various commodities.

    PubMed

    Eriksson, E; Andersen, H R; Ledin, A

    2008-08-15

    Parabens are commonly used as preservatives due to anti-bactericidal and anti-fungicidal properties and they are ubiquitously present in personal care products, pharmaceuticals, food, industrial and domestic commodities. They are suspected of causing endocrine disrupting effects to aquatic organisms and adverse effects in humans and, thus, it is highly relevant to identify and quantify their sources and transportation pathways in the urban environment. Here a substance flow analysis (SFA) was performed in order to map and comprehend the substances' flow on a national basis. Many household commodities were found to contain parabens; cleaning detergents, slimy toys, and water-based paint. The presence and concentration of parabens are regulated in cosmetics and food. Use of parabens in pharmaceuticals as excipients is documented in Denmark. The import of parabens is increasing; although the number of industrial parabens containing commodities is decreasing and manufacturer reports phase-out of parabens. The vast majority of the paraben containing commodities has a durability of 18-30 months, thus the average lifetime of the paraben stock is perceived to be limited. The inflow was ca. 154 tonnes via pure chemicals and 7.2-73 tonnes via commodities in 2004. This corresponds to an average wastewater concentration of 640-900 microg/L, when excluding discharge to solid waste, soil, biodegradation and metabolism. This is in the same order of magnitudes as can be found in industrial wastewater but higher than that seen in domestic wastewater. The data needed for the SFA is sparse, dispersed, and difficult to access and associated with a great deal of uncertainty.

  8. EMS-physicians' self reported airway management training and expertise; a descriptive study from the Central Region of Denmark

    PubMed Central

    2011-01-01

    Background Prehospital advanced airway management, including prehospital endotracheal intubation is challenging and recent papers have addressed the need for proper training, skill maintenance and quality control for emergency medical service personnel. The aim of this study was to provide data regarding airway management-training and expertise from the regional physician-staffed emergency medical service (EMS). Methods The EMS in this part of The Central Region of Denmark is a two tiered system. The second tier comprises physician staffed Mobile Emergency Care Units. The medical directors of the programs supplied system data. A questionnaire addressing airway management experience, training and knowledge was sent to the EMS-physicians. Results There are no specific guidelines, standard operating procedures or standardised program for obtaining and maintaining skills regarding prehospital advanced airway management in the schemes covered by this study. 53/67 physicians responded; 98,1% were specialists in anesthesiology, with an average of 17,6 years of experience in anesthesiology, and 7,2 years experience as EMS-physicians. 84,9% reported having attended life support course(s), 64,2% an advanced airway management course. 24,5% fulfilled the curriculum suggested for Danish EMS physicians. 47,2% had encountered a difficult or impossible PHETI, most commonly in a patient in cardiac arrest or a trauma patient. Only 20,8% of the physicians were completely familiar with what back-up devices were available for airway management. Conclusions In this, the first Danish study of prehospital advanced airway management, we found a high degree of experience, education and training among the EMS-physicians, but their equipment awareness was limited. Check-outs, guidelines, standard operating procedures and other quality control measures may be needed. PMID:21303510

  9. Use of SSRI and SNRI Antidepressants during Pregnancy: A Population-Based Study from Denmark, Iceland, Norway and Sweden

    PubMed Central

    Zoega, Helga; Kieler, Helle; Nørgaard, Mette; Furu, Kari; Valdimarsdottir, Unnur; Brandt, Lena; Haglund, Bengt

    2015-01-01

    Background The purpose was to describe utilization of selective serotonin reuptake inhibitors (SSRIs) and serotonin–norepinephrine reuptake inhibitors (SNRIs), including trends in prevalence, characteristics of users, drug switching and changes in prescribed doses in a large group of pregnant women across four Nordic countries. Methods A drug utilization study based on linked individual-level data from the nationwide prescription- and medical birth registers in Denmark, Iceland, Norway and Sweden. The study population comprised all pregnancies in these countries, resulting in a live birth or stillbirth after gestational week 22 from January 1st 2008 to December 31st 2012 (N = 1 162 470). In addition to the main study drugs SSRIs and SNRIs, we included (concurrent) use of other antidepressants, antipsychotics, anxiolytics and hypnotics. Results A total of 38 219 (3.3%) pregnancies were exposed to SSRIs and 5 634 (0.5%) to SNRIs. Prevalence of SSRI and SNRI use varied by country (1.8% in Norway to 7.0% in Iceland). Use and prescribed dosages decreased with each passing trimester of pregnancy; prevalence was 2.7% at conception, and 2.1%, 1.7% and 1.3% respectively in 1st, 2nd and 3rd trimester. In 0.6% of pregnancies women filled a prescription before pregnancy and in every trimester. In one third of exposed pregnancies, women were also dispensed anxiolytics, hypnotics or sedatives. Conclusion Use of SSRI and SNRI use during pregnancy varied between the Nordic countries, but the overall prevalence remained low and relatively stable from 2008 to 2012. The low prevalence of use and high proportion of women who discontinue treatment in pregnancy raise questions about adequate treatment of depression in pregnant women. PMID:26657647

  10. Prevalence of glucose-6-phosphate dehydrogenase deficiency and diagnostic challenges in 1500 immigrants in Denmark examined for haemoglobinopathies.

    PubMed

    Warny, Marie; Klausen, Tobias Wirenfeldt; Petersen, Jesper; Birgens, Henrik

    2015-09-01

    Similar to the thalassaemia syndromes, glucose-6-phosphate dehydrogenase (G6PD) deficiency is highly prevalent in areas historically exposed to malaria. In the present study, we used quantitative and molecular methods to determine the prevalence of G6PD deficiency in a population of 1508 immigrants in Denmark. We found the allele frequency to be between 2.4 and 2.9% in the female immigrants. Furthermore, the mutation pattern in the studied population showed a high prevalence of the G6PD A-(202A) variant in African and African-American immigrants, a high prevalence of the G6PD Mediterranean variant in Mediterranean European and Western Asian immigrants, and substantial heterogeneity in the variants found in the Eastern Asian/Pacific immigrants. Inasmuch as many of the patients included in this investigation had various thalassaemic syndromes, we were able to evaluate the effects of the interaction between a low mean corpuscular haemoglobin (MCH) value and G6PD activity, particularly in heterozygous females. The activity level was markedly influenced by the MCH value in females with normal G6PD activity, but not in heterozygous and homozygous females. Comparison of patients with normal G6PD activity and heterozygous females indicated considerable overlap in activity levels. To help separating heterozygous females from females with wild-type genes, a DNA analysis is necessary when the female activity level is between 4.0 and 4.9 U/g hgb corresponding to 50-60% of the median activity of unaffected males.

  11. Paleomagnetic results from the Cambrian and Ordovician sediments of Bornholm (Denmark) and Southern Sweden and paleogeographical implications for Baltica

    NASA Astrophysics Data System (ADS)

    Lewandowski, Marek; Abrahamsen, Niels

    2003-11-01

    If apparent polar wander paths (APWP) cross, the question arises how to prove the older magnetization to be primary and not just a younger overprint. This problem is typically met in areas affected by percolating mineralizing fluids and/or heating due to a younger regional igneous activity. The Permian magnetic overprint is the classical example. Earlier paleomagnetic studies over the Lowermost Cambrian Nekso Sandstone Fm (NSF) of Bornholm (Denmark) yielded a characteristic remanent magnetization (ChRM) similar to the Permian directions for Baltica. Since a possible reason could be a chemical overprint, we checked whether this phenomenon did take place on a regional scale. Some samples therefore were collected from other Lower Cambrian clastics of Bornholm and Southern Scandinavia. In result we show that the well-grouped and stable ChRM of the NSF contrasts with fairly chaotic, soft, and badly preserved magnetizations of the Balka, Hardeberga, Mickwitzia, and Lingulid sandstones of Bornholm and Southern Sweden, thus not indicating widespread paleomagnetic overprint. We demonstrate that the ChRM of the NSF is most probably of syndepositional/early diagenetic origin and its similarity to the Permian direction for Baltica is only casual. We propose a normal polarity and a near-equatorial position on the Southern Hemisphere for Baltica in the early Cambrian time, as well as a more complicated trend of the APWP for this paleocontinent than envisaged by other authors. Paleomagnetic results from the Arenigian limestones of the Laesaa Formation (Bornholm) that yield excellently defined but most probably only secondary components are also presented.

  12. Recorded gonorrhoea rates in Denmark, 1900–2010: the impact of clinical testing activity and laboratory diagnostic procedures

    PubMed Central

    Lind, Inga; Hoffmann, Steen

    2015-01-01

    Objectives Assessment of the relations between recorded gonorrhoea rates and clinical testing activity and disposable diagnostic tests. Methods In Denmark, two sources of information on the epidemiology of gonorrhoea are available: (1) a mandatory clinical notification system (since 1867) comprising summary information about geographic distribution, season, age group and gender; in 1994, more detailed anonymous individualised epidemiological information was included; (2) a voluntary countrywide laboratory surveillance system for culture-confirmed cases (since 1957) comprising information about patient's age and gender, infected anatomical sites and medical setting attended. Results Both surveillance systems showed marked simultaneous changes in gonorrhoea rates, although periodically considerable under-reporting or under-diagnosing was demonstrated. The annual incidence of notified cases peaked in 1919 (474/100 000), in 1944 (583/100 000) and in 1972 (344/100 000). Since 1995, the incidence has been at a low endemic level (1.5–10/100 000) and the total male/female incidence ratios were from 3 to 7 times higher than previously recorded. Among approximately 2 million persons tested during 1974–1988 78 213 men and 63 143 women with culture-confirmed gonorrhoea were identified. During this period, pharyngeal sampling was performed in 36% of men and 25% of women with gonorrhoea; pharyngeal gonorrhoea was found in 10% and 16%, respectively; 40% and 30% of these patients had no concomitant urogenital gonorrhoea. Among men with gonorrhoea, 34% were sampled from the rectum; 9% had rectal gonorrhoea, among whom the rectum was the only infected site in 67%. Conclusions Crucial factors for case finding are clinical sampling tradition and appropriate laboratory diagnostic facilities. When case finding is insufficient, a reservoir of asymptomatic rectal or pharyngeal gonorrhoea remains unrecognised. PMID:26621510

  13. Assessment of spatial variation in drinking water iodine and its implications for dietary intake: a new conceptual model for Denmark.

    PubMed

    Voutchkova, Denitza Dimitrova; Ernstsen, Vibeke; Hansen, Birgitte; Sørensen, Brian Lyngby; Zhang, Chaosheng; Kristiansen, Søren Munch

    2014-09-15

    Iodine is essential for human health. Many countries have therefore introduced universal salt iodising (USI) programmes to ensure adequate intake for the populations. However, little attention has been paid to subnational differences in iodine intake from drinking water caused by naturally occurring spatial variations. To address this issue, we here present the results of a Danish nationwide study of spatial trends of iodine in drinking water and the relevance of these trends for human dietary iodine intake. The data consist of treated drinking water samples from 144 waterworks, representing approx. 45% of the groundwater abstraction for drinking water supply in Denmark. The samples were analysed for iodide, iodate, total iodine (TI) and other major and trace elements. The spatial patterns were investigated with Local Moran's I. TI ranges from <0.2 to 126 μg L(-1) (mean 14.4 μg L(-1), median 11.9 μg L(-1)). Six speciation combinations were found. Half of the samples (n = 71) contain organic iodine; all species were detected in approx. 27% of all samples. The complex spatial variation is attributed both to the geology and the groundwater treatment. TI >40 μg L(-1) originates from postglacial marine and glacial meltwater sand and from Campanian-Maastrichtian chalk aquifers. The estimated drinking water contribution to human intake varies from 0% to >100% of the WHO recommended daily iodine intake for adults and from 0% to approx. 50% for adolescents. The paper presents a new conceptual model based on the observed clustering of high or low drinking-water iodine concentrations, delimiting zones with potentially deficient, excessive or optimal iodine status. Our findings suggest that the present coarse-scale nationwide programme for monitoring the population's iodine status may not offer a sufficiently accurate picture. Local variations in drinking-water iodine should be mapped and incorporated into future adjustment of the monitoring and/or the USI programmes.

  14. Nationwide Experience of Treatment with Protease Inhibitors in Chronic Hepatitis C Patients in Denmark: Identification of Viral Resistance Mutations

    PubMed Central

    Sølund, Christina; Krarup, Henrik; Ramirez, Santseharay; Thielsen, Peter; Røge, Birgit T.; Lunding, Suzanne; Barfod, Toke S.; Madsen, Lone G.; Tarp, Britta; Christensen, Peer B.; Gerstoft, Jan; Laursen, Alex L.; Bukh, Jens; Weis, Nina

    2014-01-01

    Background and Aims The first standard of care in treatment of chronic HCV genotype 1 infection involving directly acting antivirals was protease inhibitors telaprevir or boceprevir combined with pegylated-interferon and ribavirin (triple therapy). Phase III studies include highly selected patients. Thus, treatment response and development of viral resistance during triple therapy in a routine clinical setting needs to be determined. The aims of this study were to investigate treatment outcome and identify sequence variations after triple therapy in patients with chronic HCV genotype 1 infection in a routine clinical setting. Methods 80 patients, who initiated and completed triple therapy in Denmark between May 2011 and November 2012, were included. Demographic data and treatment response were obtained from the Danish Database for Hepatitis B and C. Direct sequencing and clonal analysis of the RT-PCR amplified NS3 protease were performed in patients without cure following triple therapy. Results 38 (47%) of the patients achieved cure, 15 (19%) discontinued treatment due to adverse events and remained infected, and 27 (34%) experienced relapse or treatment failure of whom 15 of 21 analyzed patients had well-described protease inhibitor resistance variants detected. Most frequently detected protease variants were V36M and/or R155K, and V36M, in patients with genotype 1a and 1b infection, respectively. Conclusions The cure rate after triple therapy in a routine clinical setting was 47%, which is substantially lower than in clinical trials. Resistance variants towards protease inhibitors were seen in 71% of patients failing therapy indicating that resistance could have an important role in treatment response. PMID:25438153

  15. Quality of life and coping strategies among immigrant women living with pain in Denmark: a qualitative study

    PubMed Central

    Michaëlis, Camilla; Kristiansen, Maria; Norredam, Marie

    2015-01-01

    Objective To examine quality of life and coping strategies among immigrant women living with chronic pain. Design Qualitative content analysis based on in-depth semistructured interviews. Setting A clinic specifically targeting immigrants at a larger university hospital in Copenhagen, Denmark. Participants Non-western female immigrant patients suffering from chronic pain (n=13). Main outcome measures Experiences of the impact of chronic pain on quality of life. Results Chronic pain was perceived to have an extensive, adverse effect on all aspects of quality of life, including physical health, mental well-being and social relations. This included the ability to maintain activities of daily living and the ability to work. Chronic pain was further experienced as a cause of emotional distress, depression and altered personalities, which all had great consequences on women's social interactions, causing change and loss of social relations. A variety of coping strategies were used to cope with the pain, manage its consequences, and restore a level of health that would enable women to function and fulfil social roles. Many participants coped with the pain by altering everyday life, keeping daily activities to a minimum and taking pain-killing drugs, offering temporary relief. Seeking healthcare was another coping strategy used as an active means to assert agency and as a temporary distraction from pain. However, accessing healthcare also involved a risk of disagreement and disappointments. Conclusions Chronic pain had a severe negative impact on quality of life and necessitated alterations in everyday life and active health-seeking strategies. Implications for practice imply a need for a more holistic approach to immigrant women with chronic pain, including a family-centred approach. Further research is needed to explore similarities or differences in and between populations with diverse ethnic, socioeconomic and psychosocial backgrounds, and to assess how ethnicity and

  16. Information integration without awareness.

    PubMed

    Mudrik, Liad; Faivre, Nathan; Koch, Christof

    2014-09-01

    Information integration and consciousness are closely related, if not interdependent. But, what exactly is the nature of their relation? Which forms of integration require consciousness? Here, we examine the recent experimental literature with respect to perceptual and cognitive integration of spatiotemporal, multisensory, semantic, and novel information. We suggest that, whereas some integrative processes can occur without awareness, their scope is limited to smaller integration windows, to simpler associations, or to ones that were previously acquired consciously. This challenges previous claims that consciousness of some content is necessary for its integration; yet it also suggests that consciousness holds an enabling role in establishing integrative mechanisms that can later operate unconsciously, and in allowing wider-range integration, over bigger semantic, spatiotemporal, and sensory integration windows.

  17. Buried waste integrated demonstration technology integration process

    SciTech Connect

    Ferguson, J.S.; Ferguson, J.E.

    1992-04-01

    A Technology integration Process was developed for the Idaho National Energy Laboratories (INEL) Buried Waste Integrated Demonstration (BWID) Program to facilitate the transfer of technology and knowledge from industry, universities, and other Federal agencies into the BWID; to successfully transfer demonstrated technology and knowledge from the BWID to industry, universities, and other Federal agencies; and to share demonstrated technologies and knowledge between Integrated Demonstrations and other Department of Energy (DOE) spread throughout the DOE Complex. This document also details specific methods and tools for integrating and transferring technologies into or out of the BWID program. The document provides background on the BWID program and technology development needs, demonstrates the direction of technology transfer, illustrates current processes for this transfer, and lists points of contact for prospective participants in the BWID technology transfer efforts. The Technology Integration Process was prepared to ensure compliance with the requirements of DOE`s Office of Technology Development (OTD).

  18. Buried waste integrated demonstration technology integration process

    SciTech Connect

    Ferguson, J.S.; Ferguson, J.E.

    1992-04-01

    A Technology integration Process was developed for the Idaho National Energy Laboratories (INEL) Buried Waste Integrated Demonstration (BWID) Program to facilitate the transfer of technology and knowledge from industry, universities, and other Federal agencies into the BWID; to successfully transfer demonstrated technology and knowledge from the BWID to industry, universities, and other Federal agencies; and to share demonstrated technologies and knowledge between Integrated Demonstrations and other Department of Energy (DOE) spread throughout the DOE Complex. This document also details specific methods and tools for integrating and transferring technologies into or out of the BWID program. The document provides background on the BWID program and technology development needs, demonstrates the direction of technology transfer, illustrates current processes for this transfer, and lists points of contact for prospective participants in the BWID technology transfer efforts. The Technology Integration Process was prepared to ensure compliance with the requirements of DOE's Office of Technology Development (OTD).

  19. Integrated design of integral liquid fuel ramjet

    NASA Astrophysics Data System (ADS)

    Gu, Liangxian; Yang, Jianxin; Ma, Jia; Liu, Jingchun

    1993-04-01

    Integrated design of integral liquid fuel ramjet (ILFR) is regarded as a system of the combination of missile and ILFR, which aims at obtaining the optimum performance of the system and optimizing the parameters of both missile and ramjet. In this paper, supersonic cruise missile of medium range is taken as a calculation example. In accordance with the features of integrated ramjet, the integrated design of missile and integral ramjet are discussed here. Missile configuration and ramjet parameters are optimized and then the maximum range is obtained based on two typical cases in medium and low height cruising. Some problems related to choosing missile and ramjet parameters are also, discussed and analyzed for application in different cruise heights.

  20. Monitoring the effects of climate and agriculture intensity on nutrient fluxes in lowland streams: a comparison between temperate Denmark and subtropical Uruguay

    NASA Astrophysics Data System (ADS)

    Goyenola, Guillermo; Meerhof, Mariane; Teixeira de Mello, Franco; González-Bergonzoni, Ivan; Graeber, Daniel; Vidal, Nicolas; Mazzeo, Nestor; Ovesen, Niels; Jeppesen, Erik; Thodsen, Hans; Kronvang, Brian

    2014-05-01

    Climate is changing towards more extreme conditions all over the world. At the same time, land use is becoming more intensive worldwide and particularly in many developing countries, whereas several developed countries are trying to reduce the impacts of intensive agricultural production and lower the excessive nutrient loading and eutrophication symptoms in water bodies. In 2009, we initiated a comparative research project between the subtropical region (Uruguay) and the temperate region (Denmark) to compare the hydrology and nutrient fluxes in paired micro-catchments with extensive production or intensive agriculture. The four selected streams drained catchments of similar size (7 to 19 km2). We have established similarly equipped monitoring stations in the four micro-catchments in spring (November 2009, Uruguay; March 2010, Denmark) to monitor the effects of land use and agriculture intensity on stream hydrology and nutrient concentrations and fluxes under different climate conditions. We have conducted high frequency measurements in the four lowland streams with underwater probes (turbidity, pH, conductivity and oxygen measured every 15 minutes), fortnight grab sampling of water and automatic sampling of composite water samples for nutrient analysis (total and dissolved nitrogen and phosphorus; sampled every four hours and accumulated fortnightly). Moreover, water level and meteorological information (precipitation, air temperature, global radiation, humidity) has been recorded every 10 minutes and instantaneous flow measurements have been conducted at regular intervals, to facilitate the calculation of instantaneous discharge from continuous records of water level (stage-discharge relationships). We will show results of ca. 2 years from this comparative study between Uruguay and Denmark, and the importance of differences in climate and land use will be discussed.

  1. The police, social services and psychiatry cooperation in Denmark--a new model of working practice between governmental sectors. A description of the concept, process, practice and experience.

    PubMed

    Sestoft, D; Rasmussen, M F; Vitus, K; Kongsrud, L

    2014-01-01

    In 2004 a new model of working practice between three public sectors, the local Police Department, Social Services and Psychiatry/Mental Health Services (PSP) was introduced in the municipality of Frederiksberg, Denmark. The aim of this cooperation was to enhance support to vulnerable citizens, who do not belong solely to one of the three sectors and thereby often get lost in the system. The PSP cooperation was introduced to ensure that relevant information concerning vulnerable citizens was shared between the three sectors and to improve collaboration between the sectors involved in order to provide the needed support to the individual citizen. Due to the success of the PSP cooperation in Frederiksberg, the PSP model was implemented by law in Denmark in 2009. In order to evaluate the model, a qualitative study based on structured interviews, focus group discussions and observations, was performed in four selected municipalities in Denmark: Frederiksberg, Odense, Amager and Esbjerg. The evaluation was undertaken by the Danish National Centre for Social Research. It is concluded that the PSP cooperation draws attention to marginalized groups of citizens and helps to prevent social downfall and crime. Participants of the PSP cooperations further highlight positive changes in the cooperation between the involved sectors, which is thought to further improve the support to vulnerable citizens and thereby enhance both prevention and follow up of cases. Furthermore, the recommendations drawn from the evaluation are to adapt PSP cooperations to local conditions, avoid unnecessary red-tape, keep a constant focus on citizens' ethics, as well as involve the frontline workers in the individual sectors, i.e. those who are actually in contact with marginalized citizens.

  2. IEA Wind Task 26. Wind Technology, Cost, and Performance Trends in Denmark, Germany, Ireland, Norway, the European Union, and the United States: 2007–2012

    SciTech Connect

    Vitina, Aisma; Lüers, Silke; Wallasch, Anna-Kathrin; Berkhout, Volker; Duffy, Aidan; Cleary, Brendan; Husabø, Lief I.; Weir, David E.; Lacal-Arántegui, Roberto; Hand, Maureen; Lantz, Eric; Belyeu, Kathy; Wiser, Ryan H; Bolinger, Mark; Hoen, Ben

    2015-06-01

    The International Energy Agency Implementing Agreement for cooperation in Research, Development, and Deployment of Wind Energy Systems (IEA Wind) Task 26—The Cost of Wind Energy represents an international collaboration dedicated to exploring past, present and future cost of wind energy. This report provides an overview of recent trends in wind plant technology, cost, and performance in those countries that are currently represented by participating organizations in IEA Wind Task 26: Denmark, Germany, Ireland, Norway, and the United States as well as the European Union.

  3. Summaries of plenary, symposia, and oral sessions at the XXII World Congress of Psychiatric Genetics, Copenhagen, Denmark, 12-16 October 2014.

    PubMed

    Aas, Monica; Blokland, Gabriëlla A M; Chawner, Samuel J R A; Choi, Shing-Wan; Estrada, Jose; Forsingdal, Annika; Friedrich, Maximilian; Ganesham, Suhas; Hall, Lynsey; Haslinger, Denise; Huckins, Laura; Loken, Erik; Malan-Müller, Stefanie; Martin, Joanna; Misiewicz, Zuzanna; Pagliaroli, Luca; Pardiñas, Antonio F; Pisanu, Claudia; Quadri, Giorgia; Santoro, Marcos L; Shaw, Alex D; Ranlund, Siri; Song, Jie; Tesli, Martin; Tropeano, Maria; van der Voet, Monique; Wolfe, Kate; Cormack, Freida K; DeLisi, Lynn

    2016-02-01

    The XXII World Congress of Psychiatric Genetics, sponsored by the International Society of Psychiatric Genetics, took place in Copenhagen, Denmark, on 12-16 October 2014. A total of 883 participants gathered to discuss the latest findings in the field. The following report was written by student and postdoctoral attendees. Each was assigned one or more sessions as a rapporteur. This manuscript represents topics covered in most, but not all of the oral presentations during the conference, and contains some of the major notable new findings reported.

  4. Alternative and Integrative Medicine

    MedlinePlus

    ... Alternative & Integrative Medicine Clinical Trials GBM AGILE TTFields – Optune™ Brain Tumor Treatment Locations Treatment Side Effects & their ... Alternative & Integrative Medicine Clinical Trials GBM AGILE TTFields – Optune™ Brain Tumor Treatment Locations Treatment Side Effects & their ...

  5. The universal path integral

    NASA Astrophysics Data System (ADS)

    Lloyd, Seth; Dreyer, Olaf

    2016-02-01

    Path integrals calculate probabilities by summing over classical configurations of variables such as fields, assigning each configuration a phase equal to the action of that configuration. This paper defines a universal path integral, which sums over all computable structures. This path integral contains as sub-integrals all possible computable path integrals, including those of field theory, the standard model of elementary particles, discrete models of quantum gravity, string theory, etc. The universal path integral possesses a well-defined measure that guarantees its finiteness. The probabilities for events corresponding to sub-integrals can be calculated using the method of decoherent histories. The universal path integral supports a quantum theory of the universe in which the world that we see around us arises out of the interference between all computable structures.

  6. Discovering Integrals with Geometry.

    ERIC Educational Resources Information Center

    Alexopoulos, John; Barb, Cynthia

    2001-01-01

    Presents problems to find the integrals of logarithmic and inverse trigonometric functions early in the calculus sequence by using the Fundamental Theorem of Calculus and the concept of area, and without the use of integration by parts. (Author/ASK)

  7. Two Related Parametric Integrals

    ERIC Educational Resources Information Center

    Dana-Picard, T.

    2007-01-01

    Two related sequences of definite integrals are considered. By mixing hand-work, computer algebra system assistance and websurfing, fine connections can be studied between integrals and a couple of interesting sequences of integers. (Contains 4 tables.)

  8. Boolean integral calculus

    NASA Technical Reports Server (NTRS)

    Tucker, Jerry H.; Tapia, Moiez A.; Bennett, A. Wayne

    1988-01-01

    The concept of Boolean integration is developed, and different Boolean integral operators are introduced. Given the changes in a desired function in terms of the changes in its arguments, the ways of 'integrating' (i.e. realizing) such a function, if it exists, are presented. The necessary and sufficient conditions for integrating, in different senses, the expression specifying the changes are obtained. Boolean calculus has applications in the design of logic circuits and in fault analysis.

  9. Integrated Modeling Systems

    DTIC Science & Technology

    1989-01-01

    Summer 1979). WMSI Working Paper No. 291A. 173 Dyer , J. and R. Sarin. "Measurable Multiattribute Value Functions," Operations Research. 27:4 (July...J. McCall. "Expected Utility Maximizing Job Search," Chapter 7 of Studies in the Economics of Search, 1979, North-Holland. WMSI Working Paper No. 274...model integration, solver integration, and integration of various utilities . Model integration is further divided into four subtypes based on a four-level

  10. Integrated optics technology study

    NASA Technical Reports Server (NTRS)

    Chen, B.

    1982-01-01

    The materials and processes available for the fabrication of single mode integrated electrooptical components are described. Issues included in the study are: (1) host material and orientation, (2) waveguide formation, (3) optical loss mechanisms, (4) wavelength selection, (5) polarization effects and control, (6) laser to integrated optics coupling,(7) fiber optic waveguides to integrated optics coupling, (8) souces, (9) detectors. The best materials, technology and processes for fabrication of integrated optical components for communications and fiber gyro applications are recommended.

  11. Enumeration of Integral Tetrahedra

    NASA Astrophysics Data System (ADS)

    Kurz, Sascha

    2007-09-01

    We determine the number of integral tetrahedra with diameter d, up to isomorphism, for all d<=1000, via computer enumeration. We give an algorithm that enumerates the integral tetrahedra with diameter at most d in O(d^5) time and an algorithm that can check the canonicity of a given integral tetrahedron with at most 6 integer comparisons. For the number of isomorphism classes of integral 4x4 matrices with diameter d fulfilling the triangle inequalities we derive an exact formula.

  12. Integrated optics technology study

    NASA Technical Reports Server (NTRS)

    Chen, B.; Findakly, T.; Innarella, R.

    1982-01-01

    The status and near term potential of materials and processes available for the fabrication of single mode integrated electro-optical components are discussed. Issues discussed are host material and orientation, waveguide formation, optical loss mechanisms, wavelength selection, polarization effects and control, laser to integrated optics coupling fiber optic waveguides to integrated optics coupling, sources, and detectors. Recommendations of the best materials, technology, and processes for fabrication of integrated optical components for communications and fiber gyro applications are given.

  13. Optimizing Computer Technology Integration

    ERIC Educational Resources Information Center

    Dillon-Marable, Elizabeth; Valentine, Thomas

    2006-01-01

    The purpose of this study was to better understand what optimal computer technology integration looks like in adult basic skills education (ABSE). One question guided the research: How is computer technology integration best conceptualized and measured? The study used the Delphi method to map the construct of computer technology integration and…

  14. Sledge-Hammer Integration

    ERIC Educational Resources Information Center

    Ahner, Henry

    2009-01-01

    Integration (here visualized as a pounding process) is mathematically realized by simple transformations, successively smoothing the bounding curve into a straight line and the region-to-be-integrated into an area-equivalent rectangle. The relationship to Riemann sums, and to the trapezoid and midpoint methods of numerical integration, is…

  15. Integrated Education. Feature Issue.

    ERIC Educational Resources Information Center

    York, Jennifer, Ed.; Vandercook, Terri, Ed.

    1988-01-01

    This "feature issue" provides various perspectives on a number of integrated education topics, including successful integration practices and strategies, the changing roles of teachers, the appropriate role of research, the history and future of integrated education, and the realization of dreams of life in the mainstream for children with severe…

  16. Parametric Differentiation and Integration

    ERIC Educational Resources Information Center

    Chen, Hongwei

    2009-01-01

    Parametric differentiation and integration under the integral sign constitutes a powerful technique for calculating integrals. However, this topic is generally not included in the undergraduate mathematics curriculum. In this note, we give a comprehensive review of this approach, and show how it can be systematically used to evaluate most of the…

  17. Integrating Writing and Mathematics

    ERIC Educational Resources Information Center

    Wilcox, Brad; Monroe, Eula Ewing

    2011-01-01

    Teachers often find it difficult to integrate writing and mathematics while honoring the integrity of both disciplines. In this article, the authors present two levels of integration that teachers may use as a starting point. The first level, writing without revision, can be worked into mathematics instruction quickly and readily. The second…

  18. Institutional framework for integrated Pharmaceutical Benefits Management: results from a systematic review

    PubMed Central

    Hermanowski, Tomasz Roman; Drozdowska, Aleksandra Krystyna; Kowalczyk, Marta

    2015-01-01

    Objectives In this paper, we emphasised that effective management of health plans beneficiaries access to reimbursed medicines requires proper institutional set-up. The main objective was to identify and recommend an institutional framework of integrated pharmaceutical care providing effective, safe and equitable access to medicines. Method The institutional framework of drug policy was derived on the basis of publications obtained by systematic reviews. A comparative analysis concerning adaptation of coordinated pharmaceutical care services in the USA, the UK, Poland, Italy, Denmark and Germany was performed. Results While most European Union Member States promote the implementation of selected e-Health tools, like e-Prescribing, these efforts do not necessarily implement an integrated package. There is no single agent who would manage an insured patients’ access to medicines and health care in a coordinated manner, thereby increasing the efficiency and safety of drug policy. More attention should be paid by European Union Member States as to how to integrate various e-Health tools to enhance benefits to both individuals and societies. One solution could be to implement an integrated “pharmacy benefit management” model, which is well established in the USA and Canada and provides an integrated package of cost-containment methods, implemented within a transparent institutional framework and powered by strong motivation of the agent. PMID:26528099

  19. Approaches for integrated assessment of ecological and eutrophication status of surface waters in Nordic Countries.

    PubMed

    Andersen, Jesper H; Aroviita, Jukka; Carstensen, Jacob; Friberg, Nikolai; Johnson, Richard K; Kauppila, Pirkko; Lindegarth, Mats; Murray, Ciarán; Norling, Karl

    2016-10-01

    We review approaches and tools currently used in Nordic countries (Denmark, Finland, Norway and Sweden) for integrated assessment of 'ecological status' sensu the EU Water Framework Directive as well as assessment of 'eutrophication status' in coastal and marine waters. Integration principles for combining indicators within biological quality elements (BQEs) and combining BQEs into a final-integrated assessment are discussed. Specific focus has been put on combining different types of information into indices, since several methods are currently employed. As a consequence of the variety of methods used, comparisons across both BQEs and water categories (river, lakes and coastal waters) can be difficult. Based on our analyses, we conclude that some principles and methods for integration can be critical and that a harmonised approach should be developed. Further, we conclude that the integration principles applied within BQEs are critical and in need of harmonisation if we want a better understanding of potential transition in ecological status between surface water types, e.g. when riverine water enters a downstream lake or coastal water body.

  20. A nationwide population-based cross-sectional survey of health-related quality of life in patients with myeloproliferative neoplasms in Denmark (MPNhealthSurvey): survey design and characteristics of respondents and nonrespondents

    PubMed Central

    Brochmann, Nana; Flachs, Esben Meulengracht; Christensen, Anne Illemann; Andersen, Christen Lykkegaard; Juel, Knud; Hasselbalch, Hans Carl; Zwisler, Ann-Dorthe

    2017-01-01

    Objective The Department of Hematology, Zealand University Hospital, Denmark, and the National Institute of Public Health, University of Southern Denmark, created the first nationwide, population-based, and the most comprehensive cross-sectional health-related quality of life (HRQoL) survey of patients with myeloproliferative neoplasms (MPNs). In Denmark, all MPN patients are treated in public hospitals and treatments received are free of charge for these patients. Therefore, MPN patients receive the best available treatment to the extent of its suitability for them and if they wish to receive the treatment. The aims of this article are to describe the survey design and the characteristics of respondents and nonrespondents. Material and methods Individuals with MPN diagnoses registered in the Danish National Patient Register (NPR) were invited to participate. The registers of the Danish Civil Registration System and Statistics Denmark provided information regarding demographics. The survey contained 120 questions: validated patient-reported outcome (PRO) questionnaires and additional questions addressing lifestyle. Results A total of 4,704 individuals were registered with MPN diagnoses in the NPR of whom 4,236 were eligible for participation and 2,613 (62%) responded. Overall, the respondents covered the broad spectrum of MPN patients, but patients 70–79 years old, living with someone, of a Danish/Western ethnicity, and with a higher level of education exhibited the highest response rate. Conclusion A nationwide, population-based, and comprehensive HRQoL survey of MPN patients in Denmark was undertaken (MPNhealthSurvey). We believe that the respondents broadly represent the MPN population in Denmark. However, the differences between respondents and nonrespondents have to be taken into consideration when examining PROs from the respondents. The results of the investigation of the respondents’ HRQoL in this survey will follow in future articles. PMID:28280390

  1. Photonic Integrated Circuits

    NASA Technical Reports Server (NTRS)

    Merritt, Scott; Krainak, Michael

    2016-01-01

    Integrated photonics generally is the integration of multiple lithographically defined photonic and electronic components and devices (e.g. lasers, detectors, waveguides passive structures, modulators, electronic control and optical interconnects) on a single platform with nanometer-scale feature sizes. The development of photonic integrated circuits permits size, weight, power and cost reductions for spacecraft microprocessors, optical communication, processor buses, advanced data processing, and integrated optic science instrument optical systems, subsystems and components. This is particularly critical for small spacecraft platforms. We will give an overview of some NASA applications for integrated photonics.

  2. Short and long term mortality rates associated with first pregnancy outcome: Population register based study for Denmark 1980–2004

    PubMed Central

    Reardon, David C.; Coleman, Priscilla K.

    2012-01-01

    Summary Background There is a growing interest in examining death rates associated with different pregnancy outcomes for time periods beyond one year. Previous population studies, however, have failed to control for complete reproductive histories. In this study we seek to eliminate the potential confounding effect of unknown prior pregnancy history by examining mortality rates associated specifically with first pregnancy outcome alone. We also examine differences in mortality rates associated with early abortion and late abortions (after 12 weeks). Material/Method Medical records for the entire population of women born in Denmark between 1962 and 1991 and were alive in 1980, were linked to death certificates. Mortality rates associated with first pregnancy outcomes (delivery, miscarriage, abortion, and late abortion) were calculated. Odds ratios examining death rates based on reproductive outcomes, adjusted for age at first pregnancy and year of women’s births, were also calculated. Results A total of 463,473 women had their first pregnancy between 1980 and 2004, of whom 2,238 died. In nearly all time periods examined, mortality rates associated with miscarriage or abortion of a first pregnancy were higher than those associated with birth. Compared to women who delivered, the age and birth year adjusted cumulative risk of death for women who had a first trimester abortion was significantly higher in all periods examined, from 180 days (OR=1.84; 1.11 <95% CI <3.71) through 10 years (1.39; 1.22 <95% CI <1.61), as was the risk for women who had abortions after 12 weeks from one year (OR=4.31; 2.18 <95% CI <8.54) through 10 years (OR=2.41; 1.56 <95% CI <2.41). For women who miscarried, the risk was significantly higher for cumulative deaths through 4 years (OR=1.75; 1.34 <95% CI <2.27) and at 10 years (OR=1.48; 1.18 <95% CI <1.85). Conclusions Compared to women who delivered, women who had an early or late abortion had significantly higher mortality rates within 1

  3. Equine parasite control under prescription-only conditions in Denmark--awareness, knowledge, perception, and strategies applied.

    PubMed

    Nielsen, M K; Reist, M; Kaplan, R M; Pfister, K; van Doorn, D C K; Becher, A

    2014-07-30

    Due to widespread development of anthelmintic resistance in equine parasites, recommendations for their control are currently undergoing marked changes with a shift of emphasis toward more coprological surveillance and reduced treatment intensity. Denmark was the first nation to introduce prescription-only restrictions of anthelmintic drugs in 1999, but other European countries have implemented similar legislations over recent years. A questionnaire survey was performed in 2008 among Danish horse owners to provide a current status of practices and perceptions with relation to parasite control. Questions aimed at describing the current use of coprological surveillance and resulting anthelmintic treatment intensities, evaluating knowledge and perceptions about the importance of various attributes of parasite control, and assessing respondents' willingness to pay for advice and parasite surveillance services from their veterinarians. A total of 1060 respondents completed the questionnaire. A large majority of respondents (71.9%) were familiar with the concept of selective therapy. Results illustrated that the respondents' self-evaluation of their knowledge about parasites and their control associated significantly with their level of interest in the topic and their type of education (P<0.0001). The large majority of respondents either dewormed their horses twice a year and/or performed two fecal egg counts per horse per year. This approach was almost equally pronounced in foals, horses aged 1-3 years old, and adult horses. The respondents rated prevention of parasitic disease and prevention of drug resistance as the most important attributes, while cost and frequent fecal testing were rated least important. Respondents' actual spending on parasite control per horse in the previous year correlated significantly with the amount they declared themselves willing to spend (P<0.0001). However, 44.4% declared themselves willing to pay more than what they were spending

  4. Nitrogen cycling in a Norway spruce plantation in Denmark--a SOILN model application including organic N uptake.

    PubMed

    Beier, C; Eckersten, H; Gundersen, P

    2001-12-12

    A dynamic carbon (C) and nitrogen (N) circulation model, SOILN, was applied and tested on 7 years of control data and 3 years of manipulation data from an experiment involving monthly N addition in a Norway spruce ( Picea abies, L. Karst) forest in Denmark. The model includes two pathways for N uptake: (1) as mineral N after mineralisation of organic N, or (2) directly from soil organic matter as amino acids proposed to mimic N uptake by mycorrhiza. The model was parameterised and applied to the data from the control plot both with and without the organic N uptake included. After calibration, the models performance was tested against data from the N-addition experiment by comparing model output with measurements. The model reproduced well the overall trends in C and N pools and the N concentrations in soil solutions in the top soil layers whereas discrepancies in soil-solution concentrations in the deeper soil layers are seen. In the control data, the needle-N concentration was well reproduced except for small underestimations in some years because of drought effects not included in the model. In the N-addition experiment, SOILN reproduces the observed changes; in particular, the changes in needle-N concentrations and the overall distribution within the ecosystem of the extra added 3.5 g N m(-2) year(-1) parallel the observations. When organic N uptake is included, the simulations indicate that in the control plot receiving c. 1.9 g N m(-2) year(-1), the organic N uptake in average supplies 35% of the total plant N uptake. By addition of an extra 35 kg N ha(-1) year(-1), the organic N uptake is reduced to 16% of the total N uptake. Generally, inclusion of the pathway for organic N uptake improves model performance compared with observations for both C and N. This is because mineral N uptake alone implies a larger mineralisation rate, leading to bigger concentrations of N in the soil and soil water, bigger N losses, and net loss of c. 100 kg C ha(-1) year(-1

  5. Nitrogen responses in groundwater, surface water and air following nitrate action plans in the Netherlands and Denmark

    NASA Astrophysics Data System (ADS)

    Broers, H.; Rozemeijer, J.; Visser, A.; Kronvang, B.; Erisman, J. W.; Refsgaard, J.; Thorling, L.; Slomp, C. P.; Prommer, H.

    2012-12-01

    The emissions of nutrients to air and water tend to increase worldwide. Both The Netherlands and Denmark are notorious for large inputs of nutrients in intensive agricultural practice in the previous 60 years. However, both countries have established legislation and action programs to reduce the supply and impacts of nutrients to air, groundwater and surface waters since 1985. This presentation analyses the response of nitrogen in air, surface water and groundwater following these action programs over the period 1985-2010. Responses of agriculturally derived N in air show a significant and rapid decrease since the beginning of these programs. Responses of N concentrations in many Dutch and Danish agriculturally dominated watersheds are also rapid. A clear response of nitrate-N in groundwater was revealed by age dating the water and simulations show that this also leads to a quick response of N outflow to surface waters. The rapid response of surface water is contra dictionary to the generally accepted idea that the slow transport of the groundwater N pool tends to lengthen the time scales necessary for the full recovery of N concentrations in surface waters. We stipulate that the young and shallow component of groundwater flow can discharge previously applied N effectively which causes the improvement of shallow groundwater quality to be reflected in the quick surface water response. While delay of N discharge may be true for areas with thick unsaturated zones and very limited agricultural use close to water courses, this is clearly not the case for areas with pronounced groundwater-surface water interaction such as the Netherlands delta setting or the Danish estuarine setting. The Dutch and Danish results show that N fluxes towards air and water can be managed and effectively monitored, which may help to counteract the increasing nutrient emissions in other densely populated and intensively used parts of the world. In order to predict time scales for recovery, it

  6. Variations in chemical composition and particle size of dune sediments along the west coast of Jutland, Denmark

    NASA Astrophysics Data System (ADS)

    Saye, Samantha E.; Pye, Kenneth

    2006-01-01

    Geochemical and textural variations in frontal dune sediments along the western coast of Jutland, Denmark, have been investigated in order to identify possible sediment 'provinces' and transport pathways. An understanding of sediment sources and sinks is important for both for an understanding of the nature of sedimentary environments and for applied coastal engineering and management purposes. Four coastal sectors were identified on the basis of geochemical composition. One sector is compositionally different from the other three units, having higher concentrations of the trace elements Ni, Cr, V, Sc, Zn, Pb, Ba, Zr and many rare earth elements. Dune sediments on this section of coast also have higher Al 2O 3 to K 2O ratios and lower Al 2O 3 to Fe 2O 3 ratios, reflecting a lower content of feldspar and higher content of heavy minerals. It is inferred that different, or additional, sediment source(s) have supplied sediment to this section of coast. Beach nourishment has contributed to the observed compositional differences, but previous data obtained from the Lodbjerg area indicate that aeolian sands on this section of coast naturally have a relatively high Si, Fe and Ti content, reflecting high quartz / feldspar ratio and relatively high content of heavy minerals, compared with those on other sections of the coast. Frontal dunes along the most northern section show high abundances of K 2O, Rb and Ba, reflecting a relatively high K-feldspar content derived from local sources. Alongshore trends were also identified in the mean particle size and sorting of the frontal dunes, although there is no direct correspondence with the observed geochemical differences. Three coastal units can be identified on the basis of particle size. Frontal dune sediments in the middle section are relatively coarser and less well-sorted than those to the north and south, probably reflecting both the addition of beach nourishment material and greater exposure to strong westerly winds, which

  7. Unguided clinical and actuarial assessment of re-offending risk: a direct comparison with sex offenders in Denmark.

    PubMed

    Bengtson, Susanne; Långström, Niklas

    2007-06-01

    Meta-analyses suggest that actuarial risk assessments outperform unguided clinical judgment for prediction of recidivism in criminal offenders. However, there is a lack of direct comparisons of the predictive accuracy of clinical judgment and actuarial risk scales for sexual offenders. We followed up 121 male sex offenders (> or =18 years) subjected to pre-trial forensic psychiatric assessment in Denmark in 1978-1992 (mean post-detainment time = 16.4 years) to compare the predictive validity of unstructured clinical judgment of recidivism risk with that of the well-established Static-99 (Hanson and Thornton, Law and Human Behavior 24:119-136, 2000) and an extension of the Static-99, the Static-2002 (Hanson and Thornton, Notes on the development of Static-2002 (Rep. No. 2003-01), Public Safety and Emergency Preparedness Canada, Ottawa, Canada, 2003). The predictive accuracy of unguided judgment did not exceed chance for any sexual, severe sexual or any violent (sexual or non-sexual) reconviction (AUCs of the ROC curve = 0.52, 95%CI = 0.41-0.63; 0.50, 95%CI = 0.34-0.67; and 0.57, 95%CI = 0.40-0.73, respectively). In contrast, all three outcomes were predicted significantly better than chance by the Static-99 (AUC = 0.62, 95%CI = 0.52-0.72; 0.72, 95%CI = 0.59-0.84; and 0.71, 95%CI = 0.56-0.86) and the Static-2002 (AUC = 0.67, 95%CI = 0.57-0.77; 0.69, 95%CI = 0.56-0.83; and 0.70, 95%CI = 0.55-0.86). Static-99 outperformed clinical judgment for sexual recidivision (chi(2) = 5.11, df = 1, p < .05). The Static-2002 was significantly more accurate for the prediction of any sexual recidivism as compared to unguided clinical judgment but its advantage fell just short of statistical significance for severe sexual recidivism (chi(2) = 3.56, df = 1, p = 0.06). When tested for recidivism within 2 years, none of the three prediction methods yielded results significantly better than chance for any outcome. This direct trial of the unguided clinical method argues against its

  8. Prevalence and characteristics of patients with low levels of low-density lipoprotein cholesterol in northern Denmark: a descriptive study

    PubMed Central

    Schmidt, Sigrun Alba Johannesdottir; Heide-Jørgensen, Uffe; Manthripragada, Angelika D; Ehrenstein, Vera

    2015-01-01

    Background With the emergence of new lipid-lowering therapies, more patients are expected to achieve substantial lowering of low-density lipoprotein cholesterol (LDL-C). However, there are limited data examining the clinical experience of patients with low (<1.3 mmol/L) or very low (<0.65 mmol/L) levels of LDL-C. To provide information on patients with low LDL-C, we identified and characterized persons with low LDL-C using data from Danish medical databases. Methods Using a population-based clinical laboratory database, we identified adults with at least one LDL-C measurement in northern Denmark between 1998 and 2011 (population approximately 1.5 million persons). Based on the lowest measurement during the study period, we divided patients into groups with low (<1.3 mmol/L), moderate (1.3–3.3 mmol/L), or high (>3.3 mmol/L) LDL-C. We described their demographic characteristics, entire comorbidity history, and 90-day prescription history prior to the lowest LDL-C value measured. Finally, we further restricted the analysis to individuals with very low LDL-C (<0.65 mmol/L). Results Among 765,503 persons with an LDL-C measurement, 23% had high LDL-C, 73% had moderate LDL-C, and 4.8% had low LDL-C. In the latter group, 9.6% (0.46% of total) had very low LDL-C. Compared with the moderate and high LDL-C categories, the low LDL-C group included more males and older persons with a higher prevalence of cardiovascular disease, diabetes, chronic pulmonary disease, ulcer disease, and obesity, as measured by hospital diagnoses or relevant prescription drugs for these diseases. Cancer and use of psychotropic drugs were also more prevalent. These patterns of distribution became even more pronounced when restricting to individuals with very low LDL-C. Conclusion Using Danish medical databases, we identified a cohort of patients with low LDL-C and found that cohort members differed from patients with higher LDL-C levels. These differences may be explained by various factors

  9. Volcano-climate interactions during the PETM and U-Pb dating from the Fur Formation, Denmark

    NASA Astrophysics Data System (ADS)

    Jones, Morgan; Augland, Lars; Svensen, Henrik; Tegner, Christian; Planke, Sverre; Willumsen, Pi

    2016-04-01

    The Palaeocene-Eocene Thermal Maximum (PETM) at ~56 Ma is one of the most extreme global warming events in Earth's history. Vast quantities of CO2 and CH4 were released to the atmosphere, causing a rapid (within 20,000 years) 5-6 °C warming that persisted for ~170,000 years. The PETM occurred during an abnormally warm period in Earth history, and was followed by other hyperthermal events later in the Eocene. The PETM also coincided with the second and major pulse of magmatism from the North Atlantic Igneous Province (NAIP) during the break-up of Laurentia and Eurasia at 54-56 Ma. Evidence of explosive volcanism is prevalent at Fur, an island in northern Denmark, where over 180 distinct >1 cm thick ash horizons are preserved in a shallow marine succession (numbered from #-39 to #+140). These ash layers are believed to have originated from volcanic centres in east Greenland and western UK, which indicates that that they were formed during very large volcanic eruptions. Here we present the results of two key sections of the Fur Formation: a beach section at Stolleklint that includes sediment deposited syn-PETM, and a quarry section at Jenshøj that encompasses post-PETM sediments. A detailed chemostratigraphic log of δ13C (TOC) and δ15N values through the section suggests that there may be part of sequence missing, either through glaciotectonism or a depositional hiatus. The δ13C values around ash #-33 are typical of the PETM negative carbon isotope excursion (-31 to -32 ‰), yet are back to background values of ~-26 ‰ just four metres up section. The quarry section around ash #+19 displays further variations in δ13C values, suggesting a coincidence with one of the later Eocene hyperthermal events. High precision U-Pb dating of magmatic zircons from ash layer #+19 conforms to a post-PETM depositional age, giving a mean deposition rate of approximately ~5 cm kyr-1. The correlation between the largest ash layers (#-33 and #+19) and the largest perturbations to

  10. Traffic-Related Air Pollution and Parkinson’s Disease in Denmark: A Case–Control Study

    PubMed Central

    Ritz, Beate; Lee, Pei-Chen; Hansen, Johnni; Lassen, Christina Funch; Ketzel, Matthias; Sørensen, Mette; Raaschou-Nielsen, Ole

    2015-01-01

    Background Very little is currently known about air pollutants’ adverse effects on neurodegenerative diseases even though recent studies have linked particulate exposures to brain pathologies associated with Parkinson’s and Alzheimer’s disease. Objective In the present study, we investigated long-term exposure to traffic-related air pollution and Parkinson’s disease. Methods In a case–control study of 1,696 Parkinson’s disease (PD) patients identified from Danish hospital registries and diagnosed 1996–2009 and 1,800 population controls matched by sex and year of birth, we assessed long-term traffic-related air pollutant exposures (represented by nitrogen dioxide; NO2) from a dispersion model, using residential addresses from 1971 to the date of diagnosis or first cardinal symptom for cases and the corresponding index date for their matched controls. Odds ratios (ORs) and 95% confidence intervals (CIs) were estimated with logistic regression, adjusting for matching factors and potential confounders. Results We found ambient air pollution from traffic sources to be associated with risk of PD, with a 9% higher risk (95% CI: 3, 16.0%) per interquartile range increase (2.97 μg/m3) in modeled NO2. For participants living for ≥ 20 years in the capital city, ORs were larger (OR = 1.21; 95% CI: 1.11, 1.31) than in provincial towns (OR = 1.10; 95% CI: 0.97, 1.26), whereas there was no association among rural residents. Conclusions Our findings raise concerns about potential effects of air pollution from traffic and other sources on the risk of PD, particularly in populations with high or increasing exposures. Citation Ritz B, Lee PC, Hansen J, Funch Lassen C, Ketzel M, Sørensen M, Raaschou-Nielsen O. 2016. Traffic-related air pollution and Parkinson’s disease in Denmark: a case–control study. Environ Health Perspect 124:351–356; http://dx.doi.org/10.1289/ehp.1409313 PMID:26151951

  11. Sulfur and oxygen isotope study of sulfate reduction in experiments with natural populations from Fællestrand, Denmark

    NASA Astrophysics Data System (ADS)

    Farquhar, James; Canfield, Don E.; Masterson, Andrew; Bao, Huiming; Johnston, David

    2008-06-01

    This study investigates the sulfur and oxygen isotope fractionations of dissimilatory sulfate reduction and works to reconcile the relationships between the oxygen and sulfur isotopic and elemental systems. We report results of experiments with natural populations of sulfate-reducing bacteria using sediment and seawater from a marine lagoon at Fællestrand on the northern shore of the island of Fyn, Denmark. The experiments yielded relatively large magnitude sulfur isotope fractionations for dissimilatory sulfate reduction (up to approximately 45‰ for 34S/32S) with higher δ18O accompanying higher δ34S, similar to that observed in previous studies. The seawater used in the experiments was spiked by addition of 17O-labeled water and the 17O content of residual sulfate was found to depend on the fraction of sulfate reduced in the experiments. The 17O data provides evidence for recycling of sulfur from metabolic intermediates and for an 18O/16O fractionation of ∼25-30‰ for dissimilatory sulfate reduction. The close correlation between the 17O data and the sulfur isotope data suggests that isotopic exchange between cell water and external water (reactor water) was rapid under experimental conditions. The molar ratio of oxygen exchange to sulfate reduction was found to be about 2.5. This value is slightly lower than observed in studies of natural ecosystems [e.g., Wortmann U. G., Chernyavsky B., Bernasconi S. M., Brunner B., Böttcher M. E. and Swart P. K. (2007) Oxygen isotope biogeochemistry of pore water sulfate in the deep biosphere: dominance of isotope exchange reactions with ambient water during microbial sulfate reduction (ODP Site 1130). Geochim. Cosmochim. Acta71, 4221-4232]. Using recent models of sulfur isotope fractionations we find that our combined sulfur and oxygen isotopic data places constraints on the proportion of sulfate recycled to the medium (78-96%), the proportion of sulfur intermediate sulfite that was recycled by way of APS to sulfate

  12. Changes in soil water balance following afforestation of former arable soils in Denmark as evaluated using the DAISY model

    NASA Astrophysics Data System (ADS)

    Salazar, Osvaldo; Hansen, Søren; Abrahamsen, Per; Hansen, Karin; Gundersen, Per

    2013-03-01

    SummaryLand use change alters water and element cycles, but the changes in these cycles after conversion, for example, from cropland to forest are not fully described in hydrological and nutrient transport models, which usually describe either cropland or forest stands. In the European Union future afforestation is likely to occur on abandoned cropland, and evaluation of the future impacts of this land use change will require projections with models that include combined cropland-forest modules. This study used the agro-based DAISY model (Version 4.93) to investigate changes in the soil water balance over four decades following afforestation of a homogeneous area of former arable land on a sandy loam in Denmark. Hydrological data collected during nine hydrological years (April 2001-March 2010) were used to test the DAISY model. Monthly data on soil water content at 0-90 cm used for calibration were available from April 2001 to December 2002 for six monoculture stands of oak (age 8, 22 and 31 years) and Norway spruce (age 4, 13 and 32 years). Model performance was evaluated by considering uncertainties in model inputs using the Generalised Likelihood Uncertainty Estimation (GLUE) procedure. The GLUE estimates obtained (uncertainty bands 5% and 95%) agreed satisfactorily with measured monthly soil water content during the calibration period (April 2001-December 2002). Similarly, in the oldest oak stand, long-term monitoring observations and predictions of monthly water content were in satisfactory agreement during the period January 2003-March 2010). Sensitivity analysis showed that the DAISY model was most sensitive to the potential evapotranspiration factor and soil hydraulic parameters included in the Campbell model. Simulation results during nine hydrological years showed that 16-25% of incoming precipitation led to water recharge in the spruce stands, while the corresponding range for oak stands was 25-27%. A 35-year DAISY simulation revealed that Norway spruce

  13. A follow-up study of cancer incidence among workers in manufacture of phenoxy herbicides in Denmark.

    PubMed Central

    Lynge, E.

    1985-01-01

    The purpose of this cohort study is to shed further light on the potential carcinogenic effect indicated by a Swedish case control study of the 2,4-dichlorophenol and 4-chloro-ortho-cresol based phenoxy herbicides, unlikely to be contaminated with 2,3,7,8-tetrachlorodibenzo-p-dioxin (2,3,7,8-TCDD). In the present study it was the intention to include all persons employed in manufacture of phenoxy herbicides in Denmark before 1982. The predominant product was MCPA and only a very limited amount of 2,4,5-T was processed in one of the two factories included in the study. Registration of the cohort was based on company records, supplemented with data from a public pension scheme from 1964 onwards. Ninety-nine percent of registered employees could be followed up. Cancer cases were identified by linkage with the National Cancer Register. Totals of 3,390 males and 1,069 females were included in the study. In the analysis special attention was given to soft tissue sarcomas (STS) and malignant lymphomas (ML) which are the diagnostic groups indicated to be associated with exposure to phenoxy herbicides in the Swedish studies. Five cases of STS were observed among male employees in contrast to 1.84 expected cases. This result supports the Swedish observation of an increased risk of STS following exposure to phenoxy herbicides unlikely to be contaminated with 2,3,7,8-TCDD. However, several potential biases have to be taken into account in interpretation of this observation and these are discussed. Seven cases of ML were observed among male employees in contrast to 5.37 expected which does not support the Swedish observation of an excess risk. The total cancer risk among persons employed in manufacture and packaging of phenoxy herbicides was equivalent to the cancer risk in the Danish population. Among males thus employed 11 lung cancer cases were observed in contrast to 5.33 expected. Attention should be given to exposure to spray dried MCPA-sodium salt in the plants, but

  14. Destructuration or continuity? The daily rhythm of eating in Denmark, Finland, Norway and Sweden in 1997 and 2012.

    PubMed

    Lund, Thomas Bøker; Gronow, Jukka

    2014-11-01

    There is a widely shared belief that contemporary eating culture is undergoing a process of 'destructuration' in which collective norms guiding temporal, social, and spatial aspects of eating as well as cuisine will decline or disappear. From another theoretical perspective one could argue that shared and regular patterns are quite resistant to change because they are functionally necessary for the organization and maintenance of social actions in everyday life. Using questionnaire data from Denmark, Finland, Norway and Sweden from the years 1997 and 2012 we investigate whether culturally shared timing of eating rhythms has disappeared or declined. At the population-wide level, we find clear national peaks (occurring around breakfast, lunch, and to a lesser extent dinner) during which a great number, or even the majority, of people eat. These basic rhythms of eating are nationally specific and clearly identifiable in 1997 and 2012, and only small changes were found to have occurred over the period studied. Subsequent examination of within-country differences in daily eating rhythms identified a specific sub-population with very similar features in all countries. The sub-population deviates temporally from the collective peaks of eating, and in it conventional meal types such as breakfast and lunch are skipped to a higher extent, giving what we call an 'unsynchronized' eating pattern. Interestingly, the pattern has become more common in all countries. While the growth of this sub-population may be a sign of a coming destructuration of meal culture, further analysis suggests this is not the case. Thus, we find clear socio-structural explanations for unsynchronized eating. It is related to the social coordination of work, and unsynchronized eating tends to be abandoned over the life course: with the establishment of a family, and old age, people tend to synchronize their eating habits with collective activities in society. Coupling this with the relatively modest

  15. Meticillin-resistant Staphylococcus aureus CC398 is an increasing cause of disease in people with no livestock contact in Denmark, 1999 to 2011.

    PubMed

    Larsen, Jesper; Petersen, Andreas; Sørum, Marit; Stegger, Marc; van Alphen, Lieke; Valentiner-Branth, Palle; Knudsen, Lisbet Krause; Larsen, Lars Stehr; Feingold, Beth; Price, Lance Bradley; Andersen, Paal Skytt; Larsen, Anders Rhod; Skov, Robert Leo

    2015-01-01

    Livestock constitutes a potential reservoir of meticillin-resistant Staphylococcus aureus isolates belonging to a recently derived lineage within clonal complex 398 (MRSA CC398-IIa). Since its discovery in the early 2000s, this lineage has become a major cause of human disease in Europe, posing a serious public health challenge in countries with intensive livestock production. To retrace the history of human colonisation and infection with MRSA CC398-IIa in Denmark, we conducted a nationwide, retrospective study of MRSA isolates collected from 1999 to 2011. Among 7,429 MRSA isolates screened, we identified 416 MRSA CC398-IIa isolates. Of these, 148 were from people with infections, including 51 from patients reporting no livestock exposure. The first cases of MRSA CC398-IIa infection in Denmark occurred in 2004. Subsequently, the incidence of MRSA CC398-IIa infection showed a linear annual increase of 66% from 2004 to 2011 (from 0.09 to 1.1 per 100,000 person-years). There were clear temporal and spatial relationships between MRSA CC398-IIa-infected patients with and without livestock exposure. These findings suggest substantial dissemination of MRSA CC398-IIa from livestock or livestock workers into the Danish community and underscore the need for strategies to control its spread both on and off the farm.

  16. Social inequality and incidence of and survival from tumours of the central nervous system in a population-based study in Denmark, 1994-2003.

    PubMed

    Schmidt, Lisbeth Samsø; Nielsen, Hanne; Schmiedel, Sven; Johansen, Christoffer

    2008-09-01

    We investigated the effects of socioeconomic, demographic and health-related indicators on the incidence of and survival from tumours of the central nervous system (CNS) diagnosed in 1994-2003 with follow-up through 2006 in Denmark using information from nationwide Danish administrative registers. The analyses were based on data on 5622 patients with CNS tumours in a cohort of 2.7 million people born between 1925 and 1973 and aged >or=30 years. Socioeconomic and demographic factors were not associated with the incidence of CNS tumours, except for a significantly increased incidence rate ratio (IRR) amongst men in the agricultural class (IRR, 1.23; 95% CI, 1.04-1.45). The 1- and 5-year survival was significantly longer in higher socioeconomic groups, as assessed by education, income, affiliation to the work market and size of dwelling. Socioeconomic position does not affect the incidence of CNS tumours but appears to be a prognostic factor for survival from CNS tumours in Denmark.

  17. Phenotypic and genotypic characters of isolates of Pasteurella multocida obtained from back-yard poultry and from two outbreaks of avian cholera in avifauna in Denmark.

    PubMed

    Christensen, J P; Dietz, H H; Bisgaard, M

    1998-01-01

    Two outbreaks of fowl cholera in the avifauna in Denmark, affecting primarily eiders but also cormorants, gulls and oyster-catchers were shown to be caused by the same clone of Pasteurella multocida ssp. multocida by restriction enzyme analysis (REA) and ribotyping, using the enzymes HpaII and HhaI and phenotypic characterization. This observation indicated spread by migratory birds. It was shown that the outbreak clone was closely related to isolates of Pasteurella multocida ssp. multocida obtained from back-yard poultry in Denmark, including chickens, pheasants, turkeys and ducks. The only detectable difference between the outbreak clone and some of these strains concerned the size of one fragment. These results indicate a possible exchange of P. multocida ssp. multocida between populations of wild birds and back-yard poultry. Among the DNA fingerprinting methods used, restriction enzyme analysis offered the highest discrimination among thirty strains obtained from back-yard poultry. The restriction enzymes HpaII and HhaI generated almost the same number of profile types, 17 and 15 respectively, but only HpaII differentiated the outbreak clone from the group of closely related strains isolated from back-yard poultry. Ribotyping, using the same enzymes, resulted in 12 and 10 different profile types, respectively. The outbreak isolates did not harbour any plasmids, while six out of the 30 strains originating from back-yard poultry (20%) carried a cryptic plasmid of approximately 3.4 kb.

  18. Influence of smoking habits and place of residence on the risk of lung cancer among workers in one rock-wool producing plant in Denmark.

    PubMed

    Olsen, J H; Jensen, O M; Kampstrup, O

    1986-01-01

    Cancer incidence was studied among 5,317 employees in one rock-wool production plant in Denmark. During the period 1943--1982 a marginally significant excess of 240 cancer cases was observed versus 211.0 cases expected. Among the subgroup of male workers an increasing risk with time since first employment was observed for cancer of the buccal cavity and pharynx, cancer of the respiratory system, and cancer of the bladder, of which only the excess of the first-mentioned reached significance. The increased risk of lung cancer among male workers with 20 or more years since first employment, which was not significantly in excess of 1.0, although still compatible with a two- to threefold increase according to conventional 95% confidence limits, could not be explained by deviations in local lung cancer incidence, place of residence among the rock-wool male workers, or smoking habits prevailing among unskilled workers in the eastern part of Denmark. The number of cases, however, was too small to exclude the effect of chance in this single investigation.

  19. Increased Incidence Rate of Trauma- and Stressor-Related Disorders in Denmark After the September 11, 2001, Terrorist Attacks in the United States.

    PubMed

    Hansen, Bertel T; Østergaard, Søren D; Sønderskov, Kim M; Dinesen, Peter T

    2016-10-01

    The terrorist attacks that occurred on September 11, 2001 (hereafter referred to as 9/11) in the United States had a profound impact on the physical and mental health of Americans, but the effects beyond the United States are largely unknown. To understand the wider aftermath, we examined the consequences of the 9/11 attacks on mental disorders in the Kingdom of Denmark. Utilizing population data from the Danish Psychiatric Central Research Register from 1995 to 2012, we used a time-series intervention approach to estimate the change in the incidence rate of mental disorders after the 9/11 attacks. Based on analyses of 1,448,250 contacts with psychiatric services, we found that the attacks were followed by an immediate 16% increase in the incidence rate of trauma- and stressor-related disorders. This surge dissipated approximately a year after 9/11. In contrast, no similar increases were found for other disorders. This is consistent with the prominent role of external stressors in the etiology of trauma- and stressor-related disorders. The results indicate that the effects of 9/11 on mental disorders extended across the Atlantic Ocean to Denmark. Thus, the impact of terrorist attacks on mental health is likely not limited to inhabitants of the country under attack; it also extends to people far away and without immediate relation to it.

  20. Shape of the association between income and mortality: a cohort study of Denmark, Finland, Norway and Sweden in 1995 and 2003

    PubMed Central

    Mortensen, Laust H; Rehnberg, Johan; Dahl, Espen; Diderichsen, Finn; Elstad, Jon Ivar; Martikainen, Pekka; Rehkopf, David; Tarkiainen, Lasse; Fritzell, Johan

    2016-01-01

    Objectives Prior work has examined the shape of the income–mortality association, but work has not compared gradients between countries. In this study, we focus on changes over time in the shape of income–mortality gradients for 4 Nordic countries during a period of rising income inequality. Context and time differentials in shape imply that the relationship between income and mortality is not fixed. Setting Population-based cohort study of Denmark, Finland, Norway and Sweden. Participants We collected data on individuals aged 25 or more in 1995 (n=12.98 million individuals, 0.84 million deaths) and 2003 (n=13.08 million individuals, 0.90 million deaths). We then examined the household size equivalised disposable income at the baseline year in relation to the rate of mortality in the following 5 years. Results A steep income gradient in mortality in men and women across all age groups except the oldest old in Denmark, Finland, Norway and Sweden. From the 1990s to 2000s mortality dropped, but generally more so in the upper part of the income distribution than in the lower part. As a consequence, the shape of the income gradient in mortality changed. The shift in the shape of the association was similar in all 4 countries. Conclusions A non-linear gradient exists between income and mortality in most cases and because of a more rapid mortality decline among those with high income the income gradient has become steeper over time. PMID:28011804

  1. Efficacy of selective antenatal screening for hepatitis B among pregnant women in Denmark: is selective screening still an acceptable strategy in a low-endemicity country?

    PubMed

    Jensen, Lise; Heilmann, Carsten; Smith, Else; Wantzin, Per; Peitersen, Birgit; Weber, Tom; Krogsgaard, Kim

    2003-01-01

    The prevalence of hepatitis B virus (HBV) carriage in Denmark is unknown, but expected to be low (0.1%). This study aimed to evaluate the efficacy of selective antenatal screening for HBV infection and the epidemiology of HBV and hepatitis C virus (HCV) among pregnant women. 4098 women were included in the study. Blood tests were examined for hepatitis B surface antigen (HBsAg), anti-hepatitis B core antigen (HBc) and anti-HCV. Case records were studied to evaluate whether patients at risk for HBV infection had been tested. Among the 4098 women, 18 10.4%, 95% confidence interval (95% CI) 0.3-0.71 were HBsAg positive. All had a risk factor for HBV infection. Only 13 (72%) were identified as HBsAg positive in the selective screening programme. 115 women (2.8%, 95% CI 2.3-3.4) were anti-HBc positive only. 95 (83%) were at risk for HBV. Only 72 of these (63%) were tested for HBsAg. The screening programme in this area of Denmark did not pick up one-third of pregnant women at risk of HBV.

  2. Can assisted reproductive technologies help to offset population ageing? An assessment of the demographic and economic impact of ART in Denmark and UK.

    PubMed

    Hoorens, S; Gallo, F; Cave, J A K; Grant, J C

    2007-09-01

    Governments worldwide are searching for ways to cope with ageing populations as the demographic shift towards fewer and later births takes hold. The potential contribution of assisted reproductive technologies (ART) to increasing fertility rates has not yet been explored. This paper describes a preliminary study into the impact ART policies might have on population ageing. A deterministic model is developed to quantify the effects of ART policies on total fertility rate (TFR), and tested using data from the UK and Denmark. The population structure for 2050 is modelled to translate fertility rates into time-dependent population dynamics, and the costs of potential ART policies are investigated. If access to ART in the UK were increased to the level of Denmark, the TFR would increase by 0.04, from 1.64 to 1.68. The cumulative effect on the population structure would be a 1.7% decrease in old-age dependency ratio in 2050. Although the empirical models do not include behavioural components, the results demonstrate that ART does have potential to contribute to TFR and influence population structure, and that the direct costs associated with adopting ART as a population policy are comparable with those of existing policies commonly used by governments to influence fertility.

  3. The road to success. Long-term prognosis for persons living with HIV in Denmark - time trends and risk factors.

    PubMed

    Lohse, Nicolai

    2016-02-01

    detection practice. Once diagnosed, getting the full benefit of modern HIV care requires access to a good healthcare system. We compared temporal trends in quality and quantity of ART introduction in Den-mark and Greenland. Despite similar levels of health worker education and economic resources, ART implementation and mortality decline in Greenland lacked several years behind Denmark. The study reminded us that although economy may be a prerequisite for implementing an effective HIV care system, it is certainly not all it takes. The nationwide nature of the Danish HIV Cohort Study also allowed us to study a number of time trends at the population level. Despite what was feared, we found that the prevalence of triple-drug class virological failure (TCF) seemed to have stabilized after 2000; that the incidence rates of drug resistance acquisition were decreasing during 1999-2005; and that the prevalence of potential transmitters of drug-resistant HIV decreased during 1997-2004. We also looked at some of the consequences of virological failure and drug resistance and found that even modest levels of viraemia were associated with a high risk of future failure and death, and that in persons who have experienced TCF, the number and pattern of resistance mutations were independent predictors of death. Hence, despite the overall positive trends in virological failure and drug-resistance development at the population level, our findings underline the crucial importance of always having an effective treatment option available for the individual patient with drug-resistant virus. As mortality was declining for persons with access to ART and good HIV care, it became important to know how long persons with HIV could expect to live compared to the general population. We projected long-term survival and found that a 25-year old person with HIV and without hepatitis C virus (HCV) co-infection had a 50 per cent chance of surviving another 39 years, only 12.2 years less than a person in a

  4. Integrating creativity training into Problem and Project-Based Learning curriculum in engineering education

    NASA Astrophysics Data System (ADS)

    Zhou, Chunfang

    2012-10-01

    In order to foster creative engineers, a creativity training programme was carried out in medialogy education in a Problem and Project-Based Learning (PBL) environment at Aalborg University, Denmark. This paper focuses on the question of how engineering students perceive the strategy of integrating creativity training into a PBL curriculum. A total of 20 medialogy students in the training programme were interviewed. The data shows that the training programme was thought useful and students get benefits such as gaining project work skills, creative concepts and confidence of being creative. However, limitations of the programme show that only five days of training did not fit the requirements of learning skills in PBL. So the supervisors are suggested to offer more creativity techniques and process engagement to move projects forward.

  5. Death in Denmark.

    PubMed Central

    Evans, M

    1990-01-01

    Does it matter that the hearts of 'brainstem dead' patients may persist in beating spontaneously? Hostile reactions, to the Danish inclusion of cardiac criteria in the determination of death, betray reductionist views of human life at the core of 'brainstem' conceptions of death. Such views (whether centred on neurological function or on abstractions concerning 'personhood') supplant the richness of human life and death with the poverty of essentialism: and mask the lethal nature of beating-heart organ retrieval. The affirmation of cardiac criteria for death is not an alternative form of essentialism as some critics suppose, but part of an understanding of human life and death which rejects essentialism altogether. The spontaneously persistent heartbeat does not constitute human life, but most certainly counts for it. PMID:2287015

  6. The State of Denmark

    ERIC Educational Resources Information Center

    Gronn, Peter

    2008-01-01

    When an editor sanctions a set of authors to expound on what they believe is blighting the world of education, who can be sure of what they are likely to suggest? Not surprisingly, in the present instance the authors of the six papers in this collection have seized on the freedom they have been granted and have outlined a range of afflictions. The…

  7. Career Development in Denmark.

    ERIC Educational Resources Information Center

    Plant, Peter

    Decentralization is the main feature of Danish governmental structures and the education and training system. The National Council on Educational and Vocational Guidance coordinates the career development field. Local and regional career development committees are organized under this judicial umbrella. Career education takes place as early as…

  8. INTEGRAL/SPI data segmentation to retrieve source intensity variations

    NASA Astrophysics Data System (ADS)

    Bouchet, L.; Amestoy, P. R.; Buttari, A.; Rouet, F.-H.; Chauvin, M.

    2013-07-01

    Context. The INTEGRAL/SPI, X/γ-ray spectrometer (20 keV-8 MeV) is an instrument for which recovering source intensity variations is not straightforward and can constitute a difficulty for data analysis. In most cases, determining the source intensity changes between exposures is largely based on a priori information. Aims: We propose techniques that help to overcome the difficulty related to source intensity variations, which make this step more rational. In addition, the constructed "synthetic" light curves should permit us to obtain a sky model that describes the data better and optimizes the source signal-to-noise ratios. Methods: For this purpose, the time intensity variation of each source was modeled as a combination of piecewise segments of time during which a given source exhibits a constant intensity. To optimize the signal-to-noise ratios, the number of segments was minimized. We present a first method that takes advantage of previous time series that can be obtained from another instrument on-board the INTEGRAL observatory. A data segmentation algorithm was then used to synthesize the time series into segments. The second method no longer needs external light curves, but solely SPI raw data. For this, we developed a specific algorithm that involves the SPI transfer function. Results: The time segmentation algorithms that were developed solve a difficulty inherent to the SPI instrument, which is the intensity variations of sources between exposures, and it allows us to obtain more information about the sources' behavior. Based on observations with INTEGRAL, an ESA project with instruments and science data centre funded by ESA member states (especially the PI countries: Denmark, France, Germany, Italy, Spain, and Switzerland), Czech Republic and Poland with participation of Russia and the USA.

  9. ESA's Integral satellite ready for lift-off from Baikonur

    NASA Astrophysics Data System (ADS)

    2002-10-01

    ESA's INTEGRAL (International Gamma Ray Astrophysics Laboratory) satellite, will be launched by a Proton launcher from Baikonur, Kazakhstan on 17 October at 06:41 CEST (Central European Summer Time). The most sensitive gamma-ray observatory ever launched, INTEGRAL is a truly international mission involving all ESA member states plus the USA and Russia. It carries four instruments from teams led by scientists in Italy, France, Germany, Denmark and Spain to gather and analyse gamma-rays, X-rays and visible light from celestial objects. INTEGRAL will give astronomers across the world their clearest views yet of the most extreme environments in the Universe. It will detect radiation from the most violent events far away and from processes that made the Universe inhabitable. Media representatives in Europe can follow the videotransmission of the launch at ESA/Darmstadt (ESOC) in Germany, which will be acting as the main European press centre, ESA/Noordwijk (ESTEC) in the Netherlands, ESA/Frascati (ESRIN) in Italy or ESA/Villafranca (VILSPA) in Spain. At each site ESA specialists will be available for interviews. Media representatives wishing to attend are requested to complete the attached reply form and fax it to the Communication Office at the establishment of their choice. The ESA TV Service will provide video news releases and live coverage of the launch between 06:15-07:00 and 08:00-08:30 CEST. Details of the transmission schedule for the various Video News Releases can be found on http://television.esa.int The launch can also be followed live on the internet at www.esa.int/integrallaunch starting at 06:15 hrs.

  10. Faces of integration

    PubMed Central

    Williams, Paul; Sullivan, Helen

    2009-01-01

    Theme Two central themes permeate this paper—the interplay between structure and agency in integration processes and the extent to which this is mediated through sensemaking by individual actors. Case study The empirical base for the paper is provided by case study research from Wales which draws on examples of different types of integration in health and social care. The individual case studies highlight different interpretations of integration set against a background of the resources involved, processes employed and outcomes achieved. Discussion A wide ranging discussion exposes the complex interplay and dynamics between structural factors and the manner in which they enable or constrain integration, and individual actors realising their potential agency through leadership, professionalism and boundary spanning to influence outcomes. The importance of structure and agency complementing each other to determine effective integration is emphasised, together with the scope that is available for interpretation and meaning by individual actors within the contested discourse of integration. PMID:20087420

  11. SEMP Integration Project

    DTIC Science & Technology

    2006-05-24

    Prabhu R. 2000. Development of a methodology for selecting criteria and indicators of sustainable forest management: A case study on participatory ...integration framework development efforts focused on two dilemmas—integrating across field studies and relating science and practice. We summarize results from...areas, than to ecologically meaningful boundaries. 5. Discussion We sought to develop a consensus-based framework to guide the integration of varied

  12. Integrated Sensitivity Analysis Workflow

    SciTech Connect

    Friedman-Hill, Ernest J.; Hoffman, Edward L.; Gibson, Marcus J.; Clay, Robert L.

    2014-08-01

    Sensitivity analysis is a crucial element of rigorous engineering analysis, but performing such an analysis on a complex model is difficult and time consuming. The mission of the DART Workbench team at Sandia National Laboratories is to lower the barriers to adoption of advanced analysis tools through software integration. The integrated environment guides the engineer in the use of these integrated tools and greatly reduces the cycle time for engineering analysis.

  13. Path Integrals and Hamiltonians

    NASA Astrophysics Data System (ADS)

    Baaquie, Belal E.

    2014-03-01

    1. Synopsis; Part I. Fundamental Principles: 2. The mathematical structure of quantum mechanics; 3. Operators; 4. The Feynman path integral; 5. Hamiltonian mechanics; 6. Path integral quantization; Part II. Stochastic Processes: 7. Stochastic systems; Part III. Discrete Degrees of Freedom: 8. Ising model; 9. Ising model: magnetic field; 10. Fermions; Part IV. Quadratic Path Integrals: 11. Simple harmonic oscillators; 12. Gaussian path integrals; Part V. Action with Acceleration: 13. Acceleration Lagrangian; 14. Pseudo-Hermitian Euclidean Hamiltonian; 15. Non-Hermitian Hamiltonian: Jordan blocks; 16. The quartic potential: instantons; 17. Compact degrees of freedom; Index.

  14. Avionics systems integration technology

    NASA Technical Reports Server (NTRS)

    Stech, George; Williams, James R.

    1988-01-01

    A very dramatic and continuing explosion in digital electronics technology has been taking place in the last decade. The prudent and timely application of this technology will provide Army aviation the capability to prevail against a numerically superior enemy threat. The Army and NASA have exploited this technology explosion in the development and application of avionics systems integration technology for new and future aviation systems. A few selected Army avionics integration technology base efforts are discussed. Also discussed is the Avionics Integration Research Laboratory (AIRLAB) that NASA has established at Langley for research into the integration and validation of avionics systems, and evaluation of advanced technology in a total systems context.

  15. The Center for Integrated Molecular Brain Imaging (Cimbi) database.

    PubMed

    Knudsen, Gitte M; Jensen, Peter S; Erritzoe, David; Baaré, William F C; Ettrup, Anders; Fisher, Patrick M; Gillings, Nic; Hansen, Hanne D; Hansen, Lars Kai; Hasselbalch, Steen G; Henningsson, Susanne; Herth, Matthias M; Holst, Klaus K; Iversen, Pernille; Kessing, Lars V; Macoveanu, Julian; Madsen, Kathrine Skak; Mortensen, Erik L; Nielsen, Finn Årup; Paulson, Olaf B; Siebner, Hartwig R; Stenbæk, Dea S; Svarer, Claus; Jernigan, Terry L; Strother, Stephen C; Frokjaer, Vibe G

    2016-01-01

    We here describe a multimodality neuroimaging containing data from healthy volunteers and patients, acquired within the Lundbeck Foundation Center for Integrated Molecular Brain Imaging (Cimbi) in Copenhagen, Denmark. The data is of particular relevance for neurobiological research questions related to the serotonergic transmitter system with its normative data on the serotonergic subtype receptors 5-HT1A, 5-HT1B, 5-HT2A, and 5-HT4 and the 5-HT transporter (5-HTT), but can easily serve other purposes. The Cimbi database and Cimbi biobank were formally established in 2008 with the purpose to store the wealth of Cimbi-acquired data in a highly structured and standardized manner in accordance with the regulations issued by the Danish Data Protection Agency as well as to provide a quality-controlled resource for future hypothesis-generating and hypothesis-driven studies. The Cimbi database currently comprises a total of 1100 PET and 1000 structural and functional MRI scans and it holds a multitude of additional data, such as genetic and biochemical data, and scores from 17 self-reported questionnaires and from 11 neuropsychological paper/computer tests. The database associated Cimbi biobank currently contains blood and in some instances saliva samples from about 500 healthy volunteers and 300 patients with e.g., major depression, dementia, substance abuse, obesity, and impulsive aggression. Data continue to be added to the Cimbi database and biobank.

  16. Integrated bioethanol and protein production from brown seaweed Laminaria digitata.

    PubMed

    Hou, Xiaoru; Hansen, Jonas Høeg; Bjerre, Anne-Belinda

    2015-12-01

    A wild-growing glucose-rich (i.e. 56.7% glucose content) brown seaweed species Laminaria digitata, collected from the North Coast of Denmark in August 2012, was used as the feedstock for an integrated bioethanol and protein production. Glutamic acid and aspartic acid are the two most abundant amino acids in the algal protein, both with proportional content of 10% in crude protein. Only minor pretreatment of milling was used on the biomass to facilitate the subsequent enzymatic hydrolysis and fermentation. The Separate Hydrolysis and Fermentation (SHF) resulted in obviously higher ethanol yield than the Simultaneous Saccharification and Fermentation (SSF). High conversion rate at maximum of 84.1% glucose recovery by enzymatic hydrolysis and overall ethanol yield at maximum of 77.7% theoretical were achieved. Protein content in the solid residues after fermentation was enriched by 2.7 fold, with similar distributions of amino acids, due to the hydrolysis of polymers in the seaweed cell wall matrix.

  17. Integrated exploration study of Norwegian-Danish basin, northwestern Europe

    SciTech Connect

    Joergensen, N.B.; Haselton, T.M.

    1987-05-01

    The Norwegian-Danish basin (NDB) extends from offshore Norway southeast through Denmark. This study, initiated by the Danish Energy Agency to evaluate hydrocarbon potential, consists of geophysical structural and stratigraphic mapping combined with geologic source rock and reservoir analysis. Approximately 25 wells and 15,000 km of seismic data were included. Formation of the NDB resulted from uplift of the Variscan foldbelt followed by subsidence of the foreland, i.e., the NDB and the North German basin. The Ringkoebing-Fyn High, a positive feature probably established in the late Precambrian and persisting to present, separates the basins, thus constituting the southern boundary of the NDB. Northeast the basin is bounded by the Fennoscandian shield and to the west by the North Sea graben system. Following deposition of Rotliegendes eolian and fluviatile sandstones, a major Late Permian marine transgression deposited up to 2000 m of evaporites and carbonates. Early Triassic regression resulted in thick red-bed deposits. Halokinesis commencing in the Upper Triassic dominated subsequent structural development. Continued subsidence led to deposition of Early Jurassic shelf mudstones overlain by deltaic sandstones. Rising seas during Late Cretaceous allowed widespread deposition of oceanic pelagic chalk. Early Paleocene wrench movements produced inversion. Basinal downwarping during the Tertiary was accompanied by progradation from the northeast. The complex tectonic history provides numerous different structural styles and a variety of depositional environments. To date only obvious structural features have been tested. This integrated basin study demonstrates that a number of other hydrocarbon plays remain to be explored.

  18. Threshold values and management options for phosphorus in a catchment of an estuary in Denmark with poor ecological status

    NASA Astrophysics Data System (ADS)

    Kronvang, Brian; Windolf, Jørgen; Hinsby, Klaus; Markager, Stiig

    2015-04-01

    Assessment of the ecological status of an estuary in Denmark(Horsens estuary) indicate that beside reducing total N loads also total phosphorus (TP) loads should be reduced to a level corresponding to 56% of current TP loads to obtain a good ecological status as required by the EU Water Framework Directive (Hinsby et al., 2012). The estimated maximum acceptable TP load to the estuary amounting to 13 tonnes per year corresponds to a reduction of the current TP loadings (2000-2005) with an average of 10.4 tonnes P per year. The maximum allowed stream threshold TP concentration entering the estuary is then calculated to amount to 0.084 mg P L-1. A source apportionment of TP loads during the period 2000-2005 showed that point source emissions of TP contributed with 31% and diffuse sources including background loadings, agricultural losses and scattered dwellings contributed with the remaining 69% of the TP loadings to the estuary. The reduction targets for TP can be obtained by implementing different mitigation measures directed against diffuse losses in the catchment and introducing improved treatment of sewage water at point sources discharging either to freshwater or directly to the estuary. We developed a management option for the catchment and estuary that could be applied together with a reduction of the total nitrogen loadings in order to obtain a good ecological status in the Horsens estuary (Hinsby et al., 2012). The management scenario included a reduction of point source emissions of TP amounting to 4.14 tonnes P yr-1, restoration of 300 ha of riparian wetlands (3.0 tonnes P yr-1) and implementation of mandatory 10 m buffer strips with planting of trees along 300 km of watercourses (3.0 tonnes P yr-1). We find it impossible to calculate a threshold concentration for TP in groundwater within the catchment as the pathways of dissolved (leaching and groundwater discharges) and particulate (erosional) P forms are more complex than it is the case for nitrogen

  19. Surface-NMR measurements of the longitudinal relaxation time T1 in a homogeneous sandy aquifer in Skive, Denmark

    NASA Astrophysics Data System (ADS)

    Walbrecker, J.; Behroozmand, A.

    2011-12-01

    employing the pcPSR scheme and compare it to conventional T1 data. For our feasibility study we have chosen a site in Skive, Denmark, that features excellent signal/noise conditions, allowing us to collect high quality data in reasonable survey time. In addition, proximate boreholes and TEM measurements suggest a relatively homogeneous aquifer extending from 5 to more than 25m below surface. We may therefore expect roughly constant T1 relaxation times throughout the shallow aquifer, providing us a simple framework for our comparative study. We used a 50x50m surface-NMR loop and employed 16 pulse moments selected to spatially cover the shallow aquifer region. For each pulse moment, we recorded surface-NMR T1 data densely sampled at 14 delay times τ between 250 and 4'000 ms. On this high-quality data set we demonstrate that the pcPSR acquisition approach yields to a good degree homogeneous T1 relaxation times, whereas the conventional approach leads to variations in T1 that could be misinterpreted in terms of changes of aquifer characteristics. Thereby we provide first empirical evidence for the superiority of the pcPSR scheme for surface NMR T1 acquisition.

  20. Edited Responses to the Danish Narrative "Per Smed's Whip" from Readers in Denmark, Great Britain, India, and Nigeria in the Folktale Project. Folktale: A Cross-Cultural, Interdisciplinary Study of the Experience of Literature. Paper 8.

    ERIC Educational Resources Information Center

    Dollerup, Cay; And Others

    This paper, number eight in an ongoing series, is part of an interdisciplinary project on the context of reading and reading research that explores similarities and dissimilarities in the response to literature in readers from different cultures. Presented are the written responses from 129 readers in Denmark, Greenland, Great Britain, India, and…

  1. From Higher Education To Employment. Volume II: Canada, Denmark, Spain, United States = De l'enseignement superieur a l'emploi. Volume II: Canada, Danemark, Expagne, Etats-Unis.

    ERIC Educational Resources Information Center

    Organisation for Economic Cooperation and Development, Paris (France).

    This volume presents reports on the flows of graduates from higher education and on their entry into working life in Canada, Denmark, Spain and the United States. Each paper is written according to detailed guidelines designed to assemble information from many sources, to reflect the state of the art, and to illustrate a variety of approaches,…

  2. Edited Reader Responses to the Turkish Narrative "The Golden Apple" from Readers in Denmark, Greenland, Great Britain, India, and Nigeria in the Folktale Project. Folktale: A Cross-Cultural, Interdisciplinary Study of the Experience of Literature. Paper 10.

    ERIC Educational Resources Information Center

    Dollerup, Cay; And Others

    This paper, number 10 in an ongoing series, is part of an interdisciplinary project on the context of reading and reading research that explores similarities and dissimilarities in the response to literature in readers from different cultures. Presented are the written responses from 140 readers in Denmark, Greenland, Great Britain, India, and…

  3. Predictive mapping of soil organic carbon in wet cultivated lands using classification-tree based models: the case study of Denmark.

    PubMed

    Bou Kheir, Rania; Greve, Mogens H; Bøcher, Peder K; Greve, Mette B; Larsen, René; McCloy, Keith

    2010-05-01

    Soil organic carbon (SOC) is one of the most important carbon stocks globally and has large potential to affect global climate. Distribution patterns of SOC in Denmark constitute a nation-wide baseline for studies on soil carbon changes (with respect to Kyoto protocol). This paper predicts and maps the geographic distribution of SOC across Denmark using remote sensing (RS), geographic information systems (GISs) and decision-tree modeling (un-pruned and pruned classification trees). Seventeen parameters, i.e. parent material, soil type, landscape type, elevation, slope gradient, slope aspect, mean curvature, plan curvature, profile curvature, flow accumulation, specific catchment area, tangent slope, tangent curvature, steady-state wetness index, Normalized Difference Vegetation Index (NDVI), Normalized Difference Wetness Index (NDWI) and Soil Color Index (SCI) were generated to statistically explain SOC field measurements in the area of interest (Denmark). A large number of tree-based classification models (588) were developed using (i) all of the parameters, (ii) all Digital Elevation Model (DEM) parameters only, (iii) the primary DEM parameters only, (iv), the remote sensing (RS) indices only, (v) selected pairs of parameters, (vi) soil type, parent material and landscape type only, and (vii) the parameters having a high impact on SOC distribution in built pruned trees. The best constructed classification tree models (in the number of three) with the lowest misclassification error (ME) and the lowest number of nodes (N) as well are: (i) the tree (T1) combining all of the parameters (ME=29.5%; N=54); (ii) the tree (T2) based on the parent material, soil type and landscape type (ME=31.5%; N=14); and (iii) the tree (T3) constructed using parent material, soil type, landscape type, elevation, tangent slope and SCI (ME=30%; N=39). The produced SOC maps at 1:50,000 cartographic scale using these trees are highly matching with coincidence values equal to 90.5% (Map T1

  4. Holocene environmental evolution of the SE Greenland Shelf North and South of the Denmark Strait: Irminger and East Greenland current interactions

    NASA Astrophysics Data System (ADS)

    Jennings, A.; Andrews, J.; Wilson, L.

    2011-04-01

    Holocene climatic and paleoceanographic development of the SE Greenland Shelf is studied from cores MD99-2317 and MD99-2322, at sites north and south of the Denmark Strait, respectively. Lithofacies, IRD counts, calcium carbonate percentages, benthic and planktic foraminiferal assemblages and oxygen isotope analyses, and summer SSTs reveal significant climate variations in the Holocene driven by declining solar insolation and its interaction with waning continental ice sheets, and changing atmospheric pressure patterns. Large changes in the East Greenland and Irminger Currents and the Greenland Ice Sheet are manifested as a 4-part division of the Holocene. An early Holocene cold interval dominated by melting of the Greenland Ice Sheet and Polar Front retreat extends from 11.8 to 9.5 cal kyr BP. A cold interval from 9.5 to 8.1 cal kyr BP involved episodic cooling of the Irminger Current resulting from the last phases of Laurentide Ice Sheet deglaciation and delayed the Holocene optimum off East Greenland by 3 kyr relative to peak summer solar insolation, which likely helped to limit the early Holocene melting of the Greenland Ice Sheet. The period 8.1-3.5 cal kyr BP represents a climatic optimum interval of maximum Greenland Ice Sheet retreat and strong Irminger Current inflow to the Denmark Strait. Between 6.8 and 3.5 cal kyr BP, the Irminger Current penetrated further North into the Nordic Seas than has been observed in recent decades. This signal is consistent with diminished northerly winds, a weaker Greenland High and contracted subpolar gyre. By 5 cal kyr BP, periods of increased Polar Water and decreasing salinity in the Irminger Current suggest a transition toward expansion of the subpolar gyre and increased Polar Water in the EGC. The Neoglacial interval from 3.5 to 0.2 cal kyr BP was cold and variable with increased freshwater forcing from the Arctic Ocean, advance of the Greenland Ice Sheet and southward advance of the Polar Front. Enhanced northerly

  5. Designing for STEM Integration

    ERIC Educational Resources Information Center

    Berland, Leema K.

    2013-01-01

    We are increasingly seeing an emphasis on STEM integration in high school classrooms such that students will learn and apply relevant math and science content while simultaneously developing engineering habits of mind. However, research in both science education and engineering education suggests that this goal of truly integrating STEM is rife…

  6. Integration by Hyperbolic Substitution

    ERIC Educational Resources Information Center

    Price, David

    2012-01-01

    Mathematics teachers constantly encourage their students to think independently. The study of integration in calculus provides an excellent opportunity to encourage inventive investigation. In contrast to differentiation, which is predominately mechanical, integration is a more creative process. One such possibility is offered by the study of the…

  7. Integration in Hydraulics.

    ERIC Educational Resources Information Center

    Sworder, Steven C.

    This paper presents an application of integration to the field of hydraulics. An integral relation for the time required to drop the fluid contained in a cylindrical tank from one level to another using a hole in the tank wall is derived. Procedures for constructing the experimental equipment and procedures for determining the coefficient of…

  8. Hermeneutics of Integrative Knowledge.

    ERIC Educational Resources Information Center

    Shin, Un-chol

    This paper examines and compares the formation processes and structures of three types of integrative knowledge that in general represent natural sciences, social sciences, and humanities. These three types can be observed, respectively, in the philosophies of Michael Polanyi, Jurgen Habermas, and Paul Ricoeur. These types of integrative knowledge…

  9. Systems Integration (Fact Sheet)

    SciTech Connect

    DOE Solar Energy Technologies Program

    2011-10-13

    The Systems Integration (SI) subprogram works closely with industry, universities, and the national laboratories to overcome technical barriers to the large-scale deployment of solar technologies. To support these goals, the subprogram invests primarily in four areas: grid integration, technology validation, solar resource assessment, and balance of system development.

  10. Intelligent test integration system

    NASA Technical Reports Server (NTRS)

    Sztipanovits, J.; Padalkar, S.; Rodriguez-Moscoso, J.; Kawamura, K.; Purves, B.; Williams, R.; Biglari, H.

    1988-01-01

    A new test technology is described which was developed for space system integration. The ultimate purpose of the system is to support the automatic generation of test systems in real time, distributed computing environments. The Intelligent Test Integration System (ITIS) is a knowledge based layer above the traditional test system components which can generate complex test configurations from the specification of test scenarios.

  11. Integrity in Student Development

    ERIC Educational Resources Information Center

    Roberts, Dennis C.; Banta, Trudy W.

    2011-01-01

    The quest for integrity in practice and theory has been part of the evolution of student personnel work all the way back to the turn of the 20th century. This chapter seeks to take stock of the question of integrity in relation to one of the core knowledge bases used by those engaged in student affairs work today--student development. The authors…

  12. Systems Integration (Fact Sheet)

    SciTech Connect

    Not Available

    2011-10-01

    The Systems Integration (SI) subprogram works closely with industry, universities, and the national laboratories to overcome technical barriers to the large-scale deployment of solar technologies. To support these goals, the subprogram invests primarily in four areas: grid integration, technology validation, solar resource assessment, and balance of system development.

  13. System integration report

    NASA Technical Reports Server (NTRS)

    Badler, N. I.; Korein, J. D.; Meyer, C.; Manoochehri, K.; Rovins, J.; Beale, J.; Barr, B.

    1985-01-01

    Several areas that arise from the system integration issue were examined. Intersystem analysis is discussed as it relates to software development, shared data bases and interfaces between TEMPUS and PLAID, shaded graphics rendering systems, object design (BUILD), the TEMPUS animation system, anthropometric lab integration, ongoing TEMPUS support and maintenance, and the impact of UNIX and local workstations on the OSDS environment.

  14. ESPC Integrated Skill Diagnostics

    DTIC Science & Technology

    2015-09-30

    monitoring systems for gauging performance of the ESPC. This is an integral part of the overall ESPC goal of developing a global coupled system between...1 DISTRIBUTION STATEMENT A. Approved for public release; distribution is unlimited. ESPC Integrated Skill Diagnostics Maria Flatau Naval...quantitative skill metrics to assess the advancements in the Earth System Prediction Capability (ESPC). This work will also implement automated

  15. An Integrated Teaching Module.

    ERIC Educational Resources Information Center

    Samuel, Marie R.; Seiferth, Berniece B.

    This integrated teaching module provides elementary and junior high school teachers with a "hands-on" approach to studying the Anasazi Indian. Emphasis is on creative exploration that focuses on integrating art, music, poetry, writing, geography, dance, history, anthropology, sociology, and archaeology. Replicas of artifacts,…

  16. Integrated Modeling Environment

    NASA Technical Reports Server (NTRS)

    Mosier, Gary; Stone, Paul; Holtery, Christopher

    2006-01-01

    The Integrated Modeling Environment (IME) is a software system that establishes a centralized Web-based interface for integrating people (who may be geographically dispersed), processes, and data involved in a common engineering project. The IME includes software tools for life-cycle management, configuration management, visualization, and collaboration.

  17. Undulator Field Integral Measurements

    SciTech Connect

    Wolf, Zachary

    2010-12-07

    The LCLS undulator field integrals must be very small so that the beam trajectory slope and offset stay within tolerance. In order to make accurate measurements of the small field integrals, a long coil will be used. This note describes the design of the coil measurement system.

  18. Academic Research Integration System

    ERIC Educational Resources Information Center

    Surugiu, Iula; Velicano, Manole

    2008-01-01

    This paper comprises results concluding the research activity done so far regarding enhanced web services and system integration. The objective of the paper is to define the software architecture for a coherent framework and methodology for enhancing existing web services into an integrated system. This document presents the research work that has…

  19. Integrating Module - NEMS Documentation

    EIA Publications

    2014-01-01

    Provides an overview of the complete National Energy Modeling System (NEMS) model, and includes brief descriptions of the modules with which the Integrating Module interacts. The emphasis and focus, however, is on the structure and function of the Integrating Module of NEMS.

  20. The Fresnel Integrals Revisited

    ERIC Educational Resources Information Center

    Chen, Hongwei

    2009-01-01

    This note presents another elementary method to evaluate the Fresnel integrals. It is interesting to see that this technique is also strong enough to capture a number of pairs of parameter integrals. The main ingredients of the method are the consideration of some related derivatives and linear differential equations.

  1. Integrated Marketing Communications

    ERIC Educational Resources Information Center

    Black, Jim

    2004-01-01

    Integration has become a cliche in enrollment management and student services circles. The term is used to describe everything from integrated marketing to seamless services. Often, it defines organizational structures, processes, student information systems, and even communities. In Robert Sevier's article in this issue of "College and…

  2. Linear integrated circuits

    NASA Astrophysics Data System (ADS)

    Young, T.

    This book is intended to be used as a textbook in a one-semester course at a variety of levels. Because of self-study features incorporated, it may also be used by practicing electronic engineers as a formal and thorough introduction to the subject. The distinction between linear and digital integrated circuits is discussed, taking into account digital and linear signal characteristics, linear and digital integrated circuit characteristics, the definitions for linear and digital circuits, applications of digital and linear integrated circuits, aspects of fabrication, packaging, and classification and numbering. Operational amplifiers are considered along with linear integrated circuit (LIC) power requirements and power supplies, voltage and current regulators, linear amplifiers, linear integrated circuit oscillators, wave-shaping circuits, active filters, DA and AD converters, demodulators, comparators, instrument amplifiers, current difference amplifiers, analog circuits and devices, and aspects of troubleshooting.

  3. Retroviral integration: Site matters

    PubMed Central

    Demeulemeester, Jonas; De Rijck, Jan

    2015-01-01

    Here, we review genomic target site selection during retroviral integration as a multistep process in which specific biases are introduced at each level. The first asymmetries are introduced when the virus takes a specific route into the nucleus. Next, by co‐opting distinct host cofactors, the integration machinery is guided to particular chromatin contexts. As the viral integrase captures a local target nucleosome, specific contacts introduce fine‐grained biases in the integration site distribution. In vivo, the established population of proviruses is subject to both positive and negative selection, thereby continuously reshaping the integration site distribution. By affecting stochastic proviral expression as well as the mutagenic potential of the virus, integration site choice may be an inherent part of the evolutionary strategies used by different retroviruses to maximise reproductive success. PMID:26293289

  4. Integrated terahertz optoelectronics

    NASA Astrophysics Data System (ADS)

    Liang, Guozhen; Wang, Qi Jie

    2016-11-01

    Currently, terahertz (THz) optical systems are based on bulky free-space optics. This is due to the lack of a common platform onto which different THz components, e.g., source, waveguide, modulator and detector, can be monolithically integrated. With the development of THz quantum cascade laser (QCL), it has been realized that the QCL chip may be such a platform for integrated THz photonics. Here, we report our recent works where the THz QCL is integrated with passive or optoelectronic components. They are: 1) integrated graphene modulator with THz QCL achieving 100% modulation depth and fast speed; 2) phase-locked THz QCL with integrated plasmonic waveguide and subwavelength antennas realizing dynamically widely tunable polarizations.

  5. Social inequality and incidence of and survival from malignant melanoma in a population-based study in Denmark, 1994-2003.

    PubMed

    Birch-Johansen, Fatima; Hvilsom, Gitte; Kjaer, Trille; Storm, Hans

    2008-09-01

    The incidence of cutaneous malignant melanoma has increased more than that of any other cancer in most white populations during the past few decades. We investigated the effects of socioeconomic, demographic and health-related indicators on the incidence of and survival from malignant melanoma in 1994-2003 in Denmark using information from nationwide registries. The analyses were based on data on 6914 patients with malignant melanoma in a cohort of 3.22 million persons born between 1925 and 1973 and aged >or=30 years. The age- and period-standardised incidence rate was 25 and 29 per 100,000 person-years for men and women, respectively. We found an increased risk for malignant melanoma in the highest socioeconomic groups. In general, survival after a malignant melanoma was better in high socioeconomic groups and better in women than men. Our results support earlier reports that malignant melanoma is associated with higher socioeconomic position.

  6. Population density, socioeconomic environment and all-cause mortality: a multilevel survival analysis of 2.7 million individuals in Denmark.

    PubMed

    Meijer, Mathias; Kejs, Anne Mette; Stock, Christiane; Bloomfield, Kim; Ejstrud, Bo; Schlattmann, Peter

    2012-03-01

    This study examines the relative effects of population density and area-level SES on all-cause mortality in Denmark. A shared frailty model was fitted with 2.7 million persons aged 30-81 years in 2,121 parishes. Residence in areas with high population density increased all-cause mortality for all age groups. For older age groups, residence in areas with higher proportions of unemployed persons had an additional effect. Area-level factors explained considerably more variation in mortality among the elderly than among younger generations. Overall this study suggests that structural prevention efforts in neighborhoods could help reduce mortality when mediating processes between area-level socioeconomic status, population density and mortality are found.

  7. Cost-Effectiveness Analysis of Surface Flow Constructed Wetlands (SFCW) for Nutrient Reduction in Drainage Discharge from Agricultural Fields in Denmark

    NASA Astrophysics Data System (ADS)

    Gachango, F. G.; Pedersen, S. M.; Kjaergaard, C.

    2015-12-01

    Constructed wetlands have been proposed as cost-effective and more targeted technologies in the reduction of nitrogen and phosphorous water pollution in drainage losses from agricultural fields in Denmark. Using two pig farms and one dairy farm situated in a pumped lowland catchment as case studies, this paper explores the feasibility of implementing surface flow constructed wetlands (SFCW) based on their cost effectiveness. Sensitivity analysis is conducted by varying the cost elements of the wetlands in order to establish the most cost-effective scenario and a comparison with the existing nutrients reduction measures carried out. The analyses show that the cost effectiveness of the SFCW is higher in the drainage catchments with higher nutrient loads. The range of the cost effectiveness ratio on nitrogen reduction differs distinctively with that of catch crop measure. The study concludes that SFCW could be a better optimal nutrients reduction measure in drainage catchments characterized with higher nutrient loads.

  8. IEA Wind Task 26. Wind Technology, Cost and Performance Trends in Denmark, Germany, Ireland, Norway, the European Union, and the United States. 2007 - 2012

    SciTech Connect

    Vitina, Aisma; Luers, Silke; Wallasch, Anna-Kathrin; Berkhout, Volker; Duffy, Aidan; Cleary, Brendan; Husabo, Leif I.; Weir, David E.; Lacal-Arantegui, Roberto; Hand, M. Maureen; Lantz, Eric; Belyeu, Kathy; Wiser, Ryan; Bolinger, Mark; Hoen, Ben

    2015-06-12

    This report builds from a similar previous analysis (Schwabe et al., 2011) exploring the differences in cost of wind energy in 2008 among countries participating in IEA Wind Task 26 at that time. The levelized cost of energy (LCOE) is a widely recognized metric for understanding how technology, capital investment, operations, and financing impact the life-cycle cost of building and operating a wind plant. Schwabe et al. (2011) apply a spreadsheet-based cash flow model developed by the Energy Research Centre of the Netherlands (ECN) to estimate LCOE. This model is a detailed, discounted cash flow model used to represent the various cost structures in each of the participating countries from the perspective of a financial investor in a domestic wind energy project. This model is used for the present analysis as well, and comparisons are made for those countries who contributed to both reports, Denmark, Germany, and the United States.

  9. Cost-Effectiveness Analysis of Surface Flow Constructed Wetlands (SFCW) for Nutrient Reduction in Drainage Discharge from Agricultural Fields in Denmark.

    PubMed

    Gachango, F G; Pedersen, S M; Kjaergaard, C

    2015-12-01

    Constructed wetlands have been proposed as cost-effective and more targeted technologies in the reduction of nitrogen and phosphorous water pollution in drainage losses from agricultural fields in Denmark. Using two pig farms and one dairy farm situated in a pumped lowland catchment as case studies, this paper explores the feasibility of implementing surface flow constructed wetlands (SFCW) based on their cost effectiveness. Sensitivity analysis is conducted by varying the cost elements of the wetlands in order to establish the most cost-effective scenario and a comparison with the existing nutrients reduction measures carried out. The analyses show that the cost effectiveness of the SFCW is higher in the drainage catchments with higher nutrient loads. The range of the cost effectiveness ratio on nitrogen reduction differs distinctively with that of catch crop measure. The study concludes that SFCW could be a better optimal nutrients reduction measure in drainage catchments characterized with higher nutrient loads.

  10. Influence of socioeconomic factors on survival after breast cancer--a nationwide cohort study of women diagnosed with breast cancer in Denmark 1983-1999.

    PubMed

    Dalton, Susanne Oksbjerg; Ross, Lone; Düring, Maria; Carlsen, Kathrine; Mortensen, Preben Bo; Lynch, John; Johansen, Christoffer

    2007-12-01

    The reasons for social inequality in breast cancer survival are far from established. Our study aims to study the importance of a range of socioeconomic factors and comorbid disorders on survival after breast cancer surgery in Denmark where the health care system is tax-funded and uniform. All 25,897 Danish women who underwent protocol-based treatment for breast cancer in 1983-1999 were identified in a clinical database and information on socioeconomic variables and both somatic and psychiatric comorbid disorders was obtained from population-based registries. We used Cox proportional hazards models to estimate the association between socioeconomic position and overall survival and further to analyse breast cancer specific deaths in a competing risk set-up regarding all other causes of death as competing risks. The adjusted hazard ratio (HR) for death was reduced in women with higher education (HR, 0.91; 95% confidence interval (CI), 0.85-0.98), with higher income (HR, 0.93; 95% CI, 0.87-0.98) and with larger dwellings (HR, 0.90; 95% CI, 0.85-0.96 for women living in houses larger than 150 m(2)). Presence of comorbid disorders increased the HR. An interaction between income and comorbid disorders resulting in a 15% lower survival 10 year after primary surgery in poor women with low-risk breast cancer having comorbid conditions ( approximately 65%) compared to rich women with similar breast cancer prognosis and comorbid conditions ( approximately 80%) suggests that part of the explanation for the social inequality in survival after breast cancer surgery in Denmark lies in the access to and/or compliance with management of comorbid conditions in poorer women.

  11. Social inequality in incidence of and survival from cancer in a population-based study in Denmark, 1994-2003: Summary of findings.

    PubMed

    Dalton, Susanne Oksbjerg; Schüz, Joachim; Engholm, Gerda; Johansen, Christoffer; Kjaer, Susanne Krüger; Steding-Jessen, Marianne; Storm, Hans H; Olsen, Jørgen H

    2008-09-01

    The purpose of this nationwide, population register-based study was to describe variations in cancer incidence and survival by social position in a social welfare state, Denmark, on the basis of a range of socioeconomic, demographic and health-related indicators. Our study population comprised all 3.22 million Danish residents born in 1925-1973 and aged >or=30 years, who were followed up for cancer incidence in 1994-2003 and for survival in 1994-2006, yielding 147,973 cancers. The incidence increased with lower education and income, especially for tobacco- and other lifestyle-related cancers, although for cancers of the breast and prostate and malignant melanoma the association was inverse. Conversely there was a general increase in incidence among early retirement pensioners, persons living in rented housing and those living in the smallest dwellings. Also incidence rates were generally higher in persons living alone compared to those living with a partner and in the capital area compared to the rural areas. Social inequality in the prognosis of most cancers was observed, despite the equal access to health care in Denmark, with poorer relative survival related to fewer advantages, regardless of how they were measured, often most pronounced in the first year after diagnosis. Also living alone and having somatic or psychiatric comorbidity negatively impacted the relative survival after most cancers. Our study shows that inequalities in cancer incidence and survival must be addressed in all aspects of public health, with interventions both to reduce incidence and to prolong survival.

  12. Clinical Pharmacology in Denmark in 2016 - 40 Years with the Danish Society of Clinical Pharmacology and 20 Years as a Medical Speciality.

    PubMed

    Brøsen, Kim; Andersen, Stig Ejdrup; Borregaard, Jeanett; Christensen, Hanne Rolighed; Christensen, Palle Mark; Dalhoff, Kim Peder; Damkier, Per; Hallas, Jesper; Heisterberg, Jens; Jessen, Niels; Jürgens, Gesche; Kampmann, Jens Peter Konnerup; Laursen, Britt Elmedal; Laursen, Torben; Nielsen, Lars Peter; Poulsen, Birgitte Klindt; Poulsen, Henrik Enghusen; Andersen, Ljubica Vukelic; Senderovitz, Thomas; Sonne, Jesper

    2016-12-01

    The Danish Society of Clinical Pharmacology was founded in 1976, and mainly thanks to the persistent efforts of the society, clinical pharmacology became an independent medical speciality in Denmark in 1996. Since then, clinical pharmacology has gone from strength to strength. In the Danish healthcare system, clinical pharmacology has established itself as an indispensible part of the efforts to promote the rational, safe and economic use of drugs. Clinical pharmacologists are active in drug committees both in hospitals and in the primary sector. All clinical pharmacology centres offer a local medicines information service. Some centres have established an adverse drug effect manager function. Only one centre offers a therapeutic drug monitoring service. Clinical pharmacologists are responsible for the toxicological advice at the Danish Poison Information Centre at Bispebjerg University Hospital in the Capital Region. The Department of Clinical Pharmacology at Aarhus University Hospital works closely together with forensic toxicologists and pathologists, covering issues regarding illicit substances, forensic pharmacology, post-mortem toxicology, expert testimony and research. Therapeutic geriatric and psychiatric teach-inns for specialist and junior doctors are among the newest initiatives organized by clinical pharmacologists. Clinical pharmacologists work also in the Danish Medicines Agency and in the Danish pharmaceutical industry, and the latter has in particular a great growth potential for creating new jobs and career opportunities for clinical pharmacologists. As of July 2016, the Danish Society of Clinical Pharmacology has 175 members, and 70 of these are specialists in clinical pharmacology corresponding to approximately 2.5 specialists per 1000 doctors (Denmark has in total 28,000 doctors) or approximately 12 specialists per one million inhabitants.

  13. What is the association of smoking and alcohol use with the increase in social inequality in mortality in Denmark? A nationwide register-based study

    PubMed Central

    Koch, Mette Bjerrum; Diderichsen, Finn; Grønbæk, Morten; Juel, Knud

    2015-01-01

    Objectives The aim of this paper is to estimate the impact of smoking and alcohol use on the increase in social inequality in mortality in Denmark in the period 1985–2009. Design A nationwide register-based study. Setting Denmark. Participants The whole Danish population aged 30 years or more in the period 1985–2009. Primary and secondary outcome measures The primary outcome is mortality rates in relation to educational attainments calculated with and without deaths related to smoking and alcohol use. An absolute measure of inequality in mortality is applied along with a result on the direct contribution from smoking and alcohol use on the absolute difference in mortality rates. The secondary outcome is life expectancy in relation to educational attainments. Results Since 1985, Danish overall mortality rates have decreased. Alongside the improvement in mortality, the absolute difference in the mortality rate (per 100 000 persons) between the lowest and the highest educated quartile grew from 465 to 611 among men and from 250 to 386 among women. Smoking and alcohol use have caused 75% of the increase among men and 97% of the increase among women. Among men the increase was mainly caused by alcohol. In women the increase was mainly caused by smoking. Conclusions The main explanation for the increase in social inequality in mortality since the mid-1980s is smoking and alcohol use. A significant reduction in the social inequality in mortality can only happen if the prevention of smoking and alcohol use are targeted to the lower educated part of the Danish population. PMID:25967987

  14. cDNA analyses of CAPN3 enhance mutation detection and reveal a low prevalence of LGMD2A patients in Denmark.

    PubMed

    Duno, Morten; Sveen, Marie-Louise; Schwartz, Marianne; Vissing, John

    2008-08-01

    Calpainopathy or limb-girdle muscular dystrophy type 2A (LGMD2A) is generally recognized as the most prevalent form of recessive LGMD and is caused by mutations in the CAPN3 gene. Out of a cohort of 119 patients fulfilling clinical criteria for LGMD2, referred to our neuromuscular clinic, 46 were suspected to have LGMD2A, based on western blot results. Four of these patients were shown to have LGMD2I upon molecular analysis, whereas 16 of the remaining 42 patients harbored mutations in CAPN3 by both direct genomic sequencing and cDNA analyses. In 10 patients, we identified both mutant alleles. In three other, only one heterozygous mutation could be identified on the genomic level; however, CAPN3 cDNA analyses demonstrated homozygosity for the mutant allele, indicating the presence of an unidentified allele that somehow compromise correct CAPN3 RNA processing. In the three remaining patients, only a single heterozygous mutation could be identified both at the genomic level and on full-length CAPN3 cDNA. All three patients exhibited a highly abnormal western blot for calpain-3 and clinical characteristics of LGMD2A. Only three of the genetically confirmed LGMD2A patients were of Danish origin, indicating a five- to sixfold lower prevalence in Denmark compared to other European countries. A total of 16 different CAPN3 mutations were identified, of which 5 were novel. The present study demonstrates the value of cDNA analysis for CAPN3 in LGMD2A patients and indicates that calpainopathy is an uncommon cause of LGMD in the Denmark.

  15. Potential of prescription registries to capture individual-level use of aspirin and other nonsteroidal anti-inflammatory drugs in Denmark: trends in utilization 1999–2012

    PubMed Central

    Schmidt, Morten; Hallas, Jesper; Friis, Søren

    2014-01-01

    Background Due to over-the-counter availability, no consensus exists on whether adequate information on nonsteroidal anti-inflammatory drug (NSAID) use can be obtained from prescription registries. Objectives To examine utilization of aspirin and nonaspirin NSAIDs in Denmark between 1999 and 2012 and to quantify the proportion of total sales that was sold on prescription. Method Based on nationwide data from the Danish Serum Institute and the Danish National Prescription Registry, we retrieved sales statistics for the Danish primary health care sector to calculate 1-year prevalences of prescription users of aspirin or nonaspirin NSAIDs, and to estimate the corresponding proportions of total sales dispensed on prescription. Results Both low-dose aspirin and nonaspirin NSAIDs were commonly used in the Danish population between 1999 and 2012, particularly among elderly individuals. The 1-year prevalence of prescribed low-dose aspirin increased throughout the study period, notably among men. Nonaspirin NSAID use was frequent in all age groups above 15 years and showed a female preponderance. Overall, the prevalence of prescribed nonaspirin NSAIDs decreased moderately after 2004, but substantial variation according to NSAID subtype was observed; ibuprofen use increased, use of all newer selective cyclooxygenase-2 inhibitors nearly ceased after 2004, diclofenac use decreased by nearly 50% after 2008, and naproxen use remained stable. As of 2012, the prescribed proportion of individual-level NSAID sales was 92% for low-dose aspirin, 66% for ibuprofen, and 100% for all other NSAIDs. Conclusion The potential for identifying NSAID use from prescription registries in Denmark is high. Low-dose aspirin and nonaspirin NSAID use varied substantially between 1999 and 2012. Notably, use of cyclooxygenase-2 inhibitors nearly ceased, use of diclofenac decreased markedly, and naproxen use remained unaltered. PMID:24872722

  16. Increased utilisation of primary healthcare in persons exposed to severe stress in prenatal life: a national population-based study in Denmark

    PubMed Central

    Li, Jiong; Yang, Hu; Guldin, Mai-Britt; Vedsted, Peter; Vestergaard, Mogens

    2015-01-01

    Objective Recent studies have suggested that stress in a pregnant mother may affect the future health of the unborn child negatively. An excellent proxy for health problems is the use of healthcare resources. Using nationwide data, we examined whether persons born to mothers who lost a close relative during pregnancy have more contacts to general practice. Design Population-based cohort study. Setting Denmark. Participants We included all children born in Denmark from 1973 to 2002 (N=2 032 528). Exposure of prenatal stress was defined as maternal bereavement by the death of a close relative during the antenatal period. The outcome of interest was contact with general practice between 2003 and 2009 when the participants were between 1 and 35 years of age. Poisson regression was used to assess the association between exposure and outcome. Outcome measures Contacts to general practitioner. Results Overall, persons exposed to prenatal stress had 2% more GP contacts than those not exposed, primarily due to increased utilisation of healthcare services during late adolescence and early adulthood. The exposed persons born to mothers who had lost a spouse had a higher risk (relative risk (RR) 1.12, 95% CI 1.10 to 1.14) and so did those born to mothers who had lost a close relative due to unexpected death (RR 1.06, 95% CI 1.05 to 1.06). Exposed persons had more contacts to general practice in daytime and more psychometric tests, talk therapies and C reactive protein tests than unexposed persons. Conclusions Prenatal stress following maternal bereavement was associated with a slightly increased utilisation of primary healthcare, mainly due to increased healthcare needs related to mental health and infections. Understanding how stress during pregnancy influences the future health of the child is an important aspect of prenatal care. PMID:25573520

  17. Integrated assessment briefs

    SciTech Connect

    1995-04-01

    Integrated assessment can be used to evaluate and clarify resource management policy options and outcomes for decision makers. The defining characteristics of integrated assessment are (1) focus on providing information and analysis that can be understood and used by decision makers rather than for merely advancing understanding and (2) its multidisciplinary approach, using methods, styles of study, and considerations from a broader variety of technical areas than would typically characterize studies produced from a single disciplinary standpoint. Integrated assessment may combine scientific, social, economic, health, and environmental data and models. Integrated assessment requires bridging the gap between science and policy considerations. Because not everything can be valued using a single metric, such as a dollar value, the integrated assessment process also involves evaluating trade-offs among dissimilar attributes. Scientists at Oak Ridge National Laboratory (ORNL) recognized the importance and value of multidisciplinary approaches to solving environmental problems early on and have pioneered the development of tools and methods for integrated assessment over the past three decades. Major examples of ORNL`s experience in the development of its capabilities for integrated assessment are given.

  18. GMRES and integral operators

    SciTech Connect

    Kelley, C.T.; Xue, Z.Q.

    1994-12-31

    Many discretizations of integral equations and compact fixed point problems are collectively compact and strongly convergent in spaces of continuous functions. These properties not only lead to stable and convergent approximations but also can be used in the construction of fast multilevel algorithms. Recently the GMRES algorithm has become a standard coarse mesh solver. The purpose of this paper is to show how the special properties of integral operators and their approximations are reflected in the performance of the GMRES iteration and how these properties can be used to strengthen the norm in which convergence takes place. The authors illustrate these ideas with composite Gauss rules for integral equations on the unit interval.

  19. On Quantum Integrable Systems

    SciTech Connect

    Danilov, Viatcheslav; Nagaitsev, Sergei; /Fermilab

    2011-11-01

    Many quantum integrable systems are obtained using an accelerator physics technique known as Ermakov (or normalized variables) transformation. This technique was used to create classical nonlinear integrable lattices for accelerators and nonlinear integrable plasma traps. Now, all classical results are carried over to a nonrelativistic quantum case. In this paper we have described an extension of the Ermakov-like transformation to the Schroedinger and Pauli equations. It is shown that these newly found transformations create a vast variety of time dependent quantum equations that can be solved in analytic functions, or, at least, can be reduced to time-independent ones.

  20. Space Station design integration

    NASA Technical Reports Server (NTRS)

    Carlisle, Richard F.

    1988-01-01

    This paper discusses the top Program level design integration process which involves the integration of a US Space Station manned base that consists of both US and international Elements. It explains the form and function of the Program Requirements Review (PRR), which certifies that the program is ready for preliminary design, the Program Design Review (PDR), which certifies the program is ready to start the detail design, and the Critical Design Review (CDR), which certifies that the program is completing a design that meets the Program objectives. The paper also discusses experience, status to date, and plans for continued system integration through manufacturing, testing and final verification of the Space Station system performance.