Assessing the accuracy of weather radar to track intense rain cells in the Greater Lyon area, France

NASA Astrophysics Data System (ADS)

Renard, Florent; Chapon, Pierre-Marie; Comby, Jacques

2012-01-01

The Greater Lyon is a dense area located in the Rhône Valley in the south east of France. The conurbation counts 1.3 million inhabitants and the rainfall hazard is a great concern. However, until now, studies on rainfall over the Greater Lyon have only been based on the network of rain gauges, despite the presence of a C-band radar located in the close vicinity. Consequently, the first aim of this study was to investigate the hydrological quality of this radar. This assessment, based on comparison of radar estimations and rain-gauges values concludes that the radar data has overall a good quality since 2006. Given this good accuracy, this study made a next step and investigated the characteristics of intense rain cells that are responsible of the majority of floods in the Greater Lyon area. Improved knowledge on these rainfall cells is important to anticipate dangerous events and to improve the monitoring of the sewage system. This paper discusses the analysis of the ten most intense rainfall events in the 2001-2010 period. Spatial statistics pointed towards straight and linear movements of intense rainfall cells, independently on the ground surface conditions and the topography underneath. The speed of these cells was found nearly constant during a rainfall event, but depend from event to ranges on average from 25 to 66 km/h.

7th Cancer Scientific Forum of the Cancéropôle Lyon Auvergne Rhône-Alpes

PubMed Central

Pauwels, Petrus J.; Dumontet, Charles; Reichert, Janice M.; Beck, Alain; Goetsch, Liliane; Corvaïa, Nathalie; Klein, Christian; Coiffier, Bertrand; Teicher, Beverly A.

2012-01-01

The Innovative Approaches in Anti-Cancer Monoclonal Antibodies meeting, held on March 20, 2012 in Lyon, was organized by Cancéropôle Lyon Auvergne-Rhône-Alps in partnership with the French competitiveness cluster Lyonbiopôle. CLARA is one of the seven cancer research clusters within France in charge of facilitating Translational Oncology Research by taking into account the objectives of the French National Cancer Plans I and II and, in coordination with the French National Cancer Institute and local authorities (mainly Grand Lyon, Rhône County and Rhône-Alpes Region), to perform economic development of research findings. The contribution of lectures by outstanding speakers as described in this report, the organization of two-round tables: “Antibody treatment in cancer: Unmet needs in solid tumors and hematological malignancies,” and “From chimeric to more than human antibodies,” together with face-to-face meetings, was shared by over 230 participants. The lectures provided an overview of the commercial pipeline of monoclonal antibody (mAb) therapeutics for cancer; discussion of the distinction between biosimilar, biobetter and next generation therapeutic antibodies for cancer; updates on obinutuzumab and the use of mAbs in lymphoma; and discussion of antibody-drug conjugates. PMID:22684281

[The daily life of patients at the Hôtel-Dieu in Lyon in the nineteenth century].

PubMed

Bel, Jean-Christophe; Feireisen, Marie; Fessy, Michel-Henri; Broussolle, Christiane; Neidhardt, Jean-Pierre Hano; Ferrandis, Jean-Jacques

2015-01-01

In 1802 the Hôtel-Dieu in Lyons was incorporated in the so-called Hospices Civils de Lyon. This allowed the expansion and renovation of buildings, as well as the improvement of the conditions of hygiene and comfort of the patients. This hospital was devoted only to the most severely ill or injured adults. 1100 patients were treated by seven doctors, a main surgeon and his deputy, residents and sisters. Broadly speaking the evolution of surgery can be divided into two periods: that of before anesthesia and septic surgery and that of antiseptic and aseptic surgery. We have to mention Gensoul and the resection of the maxillary before anesthesia, Bonnet and Ollier who were devoted to osteo-articular surgery (Ollier's disease), Poncet who built the first aseptic theater, Jaboulay and the resident Carrel who were transplantation's pioneers, Bouveret (paroxysmal tachycardia and Bouveret syndrome), Destot who did the first medical use of X-rays in 1895.

[Doctor Albéric Pont (1870-1960). Dental surgeon, doctor and creator of the center of maxillo-facial surgery of Lyon in 1914].

PubMed

Riaud, Xavier

2008-01-01

As Stomatologist and Dental Surgeon Albéric Pont founded with six other Dental Surgeons the School of Dentistry in Lyons which he ran for a long time. When he enlisted in the French Army in 1914 he soon became aware of the extent of facial damage that occurred among the injured soldiers. His subsequent decision was to create and run a Centre for maxillofacial surgery in Lyons. He died in 1960 and left a significant scientific work as well as technical elements of surgery, dental index and devices which still bear his name.

Robert Dyer Lyons (I 826-1886), microscopist, meteorologist, physician, parliamentarian.

PubMed

Breathnach, Caoimhghin S

2008-06-01

When the attention of Robert Dyer Lyons was drawn to the medical value of the microscope in 1850, he trained himself in its use, and after annually reviewing its recent discoveries he was despatched as chief pathologist to the Army of the East in April 1855. His Report (1856) was a feather in his cap when he returned from the Crimea to Dublin and took up a professorship in the recently founded Catholic University medical school. Popularity as a teacher and success as a physician broadened his interests to national affairs, and he advocated increased funding for university education and re-afforestation. He was elected a Liberal M P for Dublin in 1880 but did not stand for re-election in 1886, the year of his death.

Changes in sensory properties and consumer acceptance of reduced fat pork Lyon-style and liver sausages containing inulin and citrus fiber as fat replacers.

PubMed

Tomaschunas, Maja; Zörb, Rebecca; Fischer, Jürgen; Köhn, Ehrhard; Hinrichs, Jörg; Busch-Stockfisch, Mechthild

2013-11-01

The effects of fat reduction in Lyon-style (25% fat) and liver sausages (30% fat) using inulin, citrus fiber and partially rice starch were studied in terms of sensory properties and consumer acceptance. Fat reduced Lyon-style sausages (3 to 17% fat) and liver sausages (3 to 20% fat) were respectively compared to the full-fat controls. Reducing fat in Lyon-style sausages decreased meat flavor, aftertaste meat flavor, greasiness and juiciness, and enhanced color intensity, spiciness, spicy aftertaste, raspy throat, coarseness and firmness scores. But adding inulin and citrus fiber led to sensory characteristics similar to the full-fat reference. Regarding liver sausages, attribute scores in greasiness, creaminess, lumpiness and foamy were decreased with fat reduction and simultaneous addition of fibers. Color intensity, spiciness, firmness and attribute furred tongue were increased. Consumer tests revealed acceptable fat reduced (32 to 90% less than control) and fiber enriched (1.0 to 5.6%) sausages. Drivers of liking were found to relate not only to high-fat but also to low-fat samples. Copyright © 2013 Elsevier Ltd. All rights reserved.

Promoting sustainable mobility by modelling bike sharing usage in Lyon

NASA Astrophysics Data System (ADS)

Tran, T. D.; Ovtracht, N.

2018-04-01

This paper aims to present a modelling of bike sharing demand at station level in the city of Lyon. Multiple linear regression models were used in order to predict the daily flows of each station. The data used in this project consists of over 6 million bike sharing trips recorded in 2011. The built environment variables used in the model are determined in a buffer zone of 300 meters around each bike sharing station. The results show that bike sharing is principally used for commuting purposes. An interesting finding is that the bike sharing network characteristics are important parameters to improve the prediction quality of the models. The present results could be useful for others cities which want to adopt a bike sharing system and also for a better planning and operation of existing systems. The approach in this paper can be useful for estimating car-sharing demand.

The Ideological Origins of the Women's College: Religion, Class, and Curriculum in the Educational Visions of Catharine Beecher and Mary Lyon

ERIC Educational Resources Information Center

Turpin, Andrea L.

2010-01-01

Historical scholarship has traditionally focused on the commonalities uniting Catharine Beecher and Mary Lyon, the two leading antebellum women's educational reformers in New England. This essay shifts that focus by contrasting their educational philosophies and exploring the implications their differences had for the development of American…

Recognition of a heritage in danger: rammed-earth architecture in Lyon city, France

NASA Astrophysics Data System (ADS)

Alex, Dorothée

2018-04-01

Historically, man has built with what he had underfoot: if the earthen construction is a tradition of 11 000 years old, the technique of the rammed earth (earth rammed in a formwork) is relatively new since it appeared for the first time in Tunisia in 814 BC. Exported in France, rammed earth is established mainly in Rhône-Alpes Region which has an ideal soil, rich in gravel, sand, silt and clay. Traditionally associated with the rural world, rammed earth heritage is also present in urban centers. The city of Lyon is one of the rare European cities to concentrate a large proportion of rammed earth buildings: the inventories made show that they are present in almost all the districts as well as in the suburban areas. This high density could be explained by the phenomenon of rural exodus experienced by Lyon during the nineteenth century. The agricultural populations, attracted by the prosperity of the city, then settled at the doors of this city, bringing their know-how by building with the cheaper and easier material available: earth. Rammed earth buildings are therefore located on bounder areas between the countryside and the city. They are thus found on lands that were once outside the city walls. With the advent of the industrial era at the end of the 19th century and the appearance of concrete, rammed earth constructions gradually disappeared. The constructions that we see today are therefore prior to 1900. Varied, ranging from detached houses to the 6-storey buildings, they stand as a testimony to a know-how that finds a particular resonance today, while the environmental and economic concerns are at the forefront. Little known, they constitute a heritage in danger that should be rediscovered.

Performance of the high speed anechoic wind tunnel at Lyon University

NASA Technical Reports Server (NTRS)

Sunyach, M.; Brunel, B.; Comte-Bellot, G.

1986-01-01

The characteristics of the feed duct, the wind tunnel, and the experiments run in the convergent-divergent anechoic wind tunnel at Lyon University are described. The wind tunnel was designed to eliminate noise from the entrance of air or from flow interactions with the tunnel walls so that noise caused by the flow-test structure interactions can be studied. The channel contains 1 x 1 x 0.2 m glass and metal foil baffles spaced 0.2 m apart. The flow is forced by a 350 kW fan in the primary circuit, and a 110 kW blower in the secondary circuit. The primary circuit features a factor of four throat reductions, followed by a 1.6 reduction before the test section. Upstream and downstream sensors permit monitoring of the anechoic effectiveness of the channel. Other sensors allow modeling of the flow structures in the tunnel. The tunnel was used to examine turbulent boundary layers in flows up to 140 m/sec, tubulence-excited vibrations in walls, and the effects of laminar and turbulent flows on the appearance and locations of noise sources.

[Mural paintings of Jean Coquet at the Desgenette Hospital in Lyon].

PubMed

Chauvin, Frédéric; Fischer, Louis-Paul

2010-01-01

René Nicolas Dufriche Desgenettes (1762-1837) became famous through two historical events: the first and most famous one is where he proved his courage by inoculating himself with the plague during the Syrian campaign in 1799; the second one, rarely represented in paintings, happened during the Russian retreat in 1812 when he was freed thanks to his reputation. Two wide fresco paintings facing each other in the hall of Desgenettes, a hospital built during World War Two, are witnesses of these two major events. Jean Coquet (1907-1990), a decorator, painter and glassblower, who worked at the Beaux-Arts School of Lyon, first as a decoration teacher than as its director, painted these two works of art. In 1946, he inserted them into an ornamental group constituted of ironworks, furniture, stained glass and ceramics. Two paintings from Antoine-Jean Gros (1771-1835) inspired these works: Bonaparte visiting the plague-stricken of Jaffa (1804) and Napoleon on the battlefield of Eylau (1808). With their academic composition and daring stylization those two frescoes represent in a modern and original way Desgenettes' life style, an archetype of what the military doctor is.

Methicillin-resistant Staphylococcus aureus in the environment of public transport: data from the metropolitan network in Lyon, France.

PubMed

Gaymard, Alexandre; Pichon, Maxime; Degaud, Michaël; Tasse, Jason; Dupieux, Céline; Laurent, Frédéric

2016-10-01

Methicillin-resistant Staphylococcus aureus (MRSA) is involved in community-acquired and nosocomial diseases. The means of MRSA transmission and dissemination in the community remain uncertain. Studies have shown that public transport systems could be a source of MRSA and may serve as a potential source for community-acquired MRSA infections. This study aimed to investigate MRSA contamination on Lyon's metropolitan network (Métro) in France. Hand-touched surfaces were sampled with sterile swabs (Transystem(®)) during a 1-day transversal study by collecting 50 samples in seven hub stations and two trains for each of the four Métro lines. Then, during a longitudinal study, one sample was collected twice daily for 30 consecutive days in the busiest and most congested hub station. All swabs were incubated in enrichment medium for 24 h and then each suspension was plated onto a chromogenic selective medium for MRSA. After 24 h at 36 °C, all presumptive MRSA colonies were tested using VITEK(®) MS to confirm identification as S. aureus as well as by Alere™ PBP2a Culture Colony Test and mecA/mecC PCR to check methicillin resistance. Of the 110 swabs tested, 24 presumptive MRSA colonies were isolated, of which 2 were confirmed as S. aureus by VITEK(®) MS. These two isolates were tested negative using the PBP2a Culture Colony Test and PCR. Unlike other foreign cities such as Lisbon, the current data suggest a low level of MRSA contamination of hand-touched surfaces on Lyon's Métro. This should be put in perspective with the low level of MRSA colonisation in the French community. Copyright © 2016 Elsevier B.V. and International Society of Chemotherapy. All rights reserved.

Satellite images of the September 2013 flood event in Lyons, Colorado

USGS Publications Warehouse

Cole, Christopher J.; Friesen, Beverly A.; Wilds, Stanley; Noble, Suzanne; Warner, Harumi; Wilson, Earl M.

2013-01-01

The U.S. Geological Survey (USGS) Special Applications Science Center (SASC) produced an image base map showing high-resolution remotely sensed data over Lyons, Colorado—a city that was severely affected by the flood event that occurred throughout much of the Colorado Front Range in September of 2013. The 0.5-meter WorldView-2 data products were created from imagery collected by DigitalGlobe on September 13 and September 24, 2013, during and following the flood event. The images shown on this map were created to support flood response efforts, specifically for use in determining damage assessment and mitigation decisions. The raw, unprocessed imagery were orthorectified and pan-sharpened to enhance mapping accuracy and spatial resolution, and reproduced onto a cartographic base map. These maps are intended to provide a snapshot representation of post-flood ground conditions, which may be useful to decisionmakers and the general public. The SASC also provided data processing and analysis support for other Colorado flood-affected areas by creating cartographic products, geo-corrected electro-optical and radar image mosaics, and GIS water cover files for use by the Colorado National Guard, the National Park Service, the U.S. Forest Service, and the flood response community. All products for this International Charter event were uploaded to the USGS Hazards Data Distribution System (HDDS) website (http://hdds.usgs.gov/hdds2/) for distribution.

Use of psychoactive substances in prison: Results of a study in the Lyon-Corbas prison, France.

PubMed

Sahajian, F; Berger-Vergiat, A; Pot, E

2017-09-01

In prison, in 2012, according to various sources, from 4 to 56% of the European inmate population used psychoactive substances (PAS). The aim of our study was to describe PAS consumption during incarceration in the prison of Lyon-Corbas, France. A transversal descriptive study was conducted between September 23rd and September 27th 2013 among all inmates of this prison. We used an anonymous self-administered questionnaire, distributed at lunchtime and collected, the same day, at dinnertime, by the mental health service personnel. Among 785 inmates present at the time of the study in the prison of Lyon-Corbas, 710 were included and the response rate was 64.4% (95% CI [60.8-67.8]). Among 457 responding inmates, 16.4% (95% CI [13.2-20.0]) reported no PAS consumption. Among 382 consumers, 74.4% (95% CI [69.8-78.5]) used tobacco, 36.8% (95% CI [32.2-41.8]) cannabis, 30.4% (95% CI [25.9-35.1]) alcohol, 7.7% (95% CI [5.2-10.6]) heroin and 10.3% (95% CI [7.5-13.6]) cocaine. Furthermore, 15% of consumers had started PAS consumption during their incarceration. Among consumers of at least one PAS other than tobacco, cannabis and alcohol, the way of consumption was sniff for 60.0% (95% CI [48.5-70.2]) and injection for 31.0% (95% CI [21.6-42.1]). Use of several PAS at the same time and sharing sniffing and/or injection paraphernalia were other risky behaviors observed; 12% (95% CI [5.8-20.4]) of drug injectors declared using chlorine to sterilize their injection paraphernalia. Our study provides worrying data about PAS consumption in prison. The measures of prohibition do not prevent this consumption. There is even an initiation of consumption of PAS for 15% of the first-time incarcerated inmates. This finding should encourage public authorities to facilitate access of inmates to the care structures in prisons, to improve drug use prevention and care programs and to develop activities (sports, cultural, educational and vocational). Copyright © 2017 Elsevier Masson SAS

A Brief Overview of the Life and Work of Lyon Henry Appleby, M.D. (1895-1970).

PubMed

Harrison, Jon; Pucci, Michael J; Cowan, Scott W; Yeo, Charles J

2016-12-01

The life and work of Dr. Lyon Henry Appleby, M.D., portrays the essence of a devoted clinician committed to scholarly excellence. Born in Deseronto, Ontario, in 1895 and passing in 1970, Dr. Appleby influenced all areas of general surgery, most notably popularizing a procedure that bears his name today. After a tour in World War I, he quickly proved himself to be a dedicated clinician with roots in academia, which translated into excellence within the Department of Surgery at St. Paul's Hospital in Vancouver, Canada. He served in various leadership roles including Chair of the Department of Surgery, President of the International College of Surgeons, and Fellow of the Royal College of Physicians and Surgeons. The Appleby procedure, or en bloc removal of the celiac axis, at the time of gastrectomy, is the technical focus of this paper, although reference is made to Appleby's extensive contributions to historical medicine.

Hepatitis A outbreak in HIV-infected MSM and in PrEP-using MSM despite a high level of immunity, Lyon, France, January to June 2017.

PubMed

Charre, Caroline; Ramière, Christophe; Roque-Afonso, Anne-Marie; Chidiac, Christian; Zoulim, Fabien; Godinot, Matthieu; Koffi, Joseph; Scholtès, Caroline; Livrozet, Jean-Michel; Hav Lyon Study Group; Cotte, Laurent

2017-11-01

Since 2016, an increase in the number of hepatitis A cases affecting mainly men who have sex with men (MSM) has been reported in low endemic countries in Europe. We calculated the attack rate in Lyon, France, in populations considered at high-risk: HIV-infected MSM and HIV-negative MSM receiving HIV pre-exposure prophylaxis (PrEP). In these populations, high level of immunity did not prevent the outbreak, indicating that vaccination should be reinforced, particularly in younger individuals.

Philanthropies croisées: a joint venture in public health at Lyon (1917-1940).

PubMed

Saunier, Pierre-Yves; Tournès, Ludovic

2009-01-01

Since the end of the First World War the Rockefeller Foundation has spearheaded a large-scale programme in the field of education for the health professions (doctors and nurses). In several countries throughout the world, but with its efforts concentrated on Europe, it has financed schools, constructed information networks, granted research scholarships and awarded training bursaries. In so doing it has not, however, been in the business of propagating an irresistible "American model," nor has it pursued a huge undertaking in disinterested aid. Through an attempt to contextualize these programmes, to bring to light the existence of common reference points, to retrace the work with local participants and to appraise cleavages within the philanthropic apparatus, this article proposes a fine-grained reading of the role of the Rockefeller Foundation at the Faculté de Médecine (Faculty of Medicine) and the Ecole d'Infirmières et d'assistantes sociales (Training School for Nurses and Social Workers) in Lyon between 1917- and 1940. It analyses these institutions in terms of the transactions, negotiations and appropriations that highlight their joint-venture character and it identifies their varied impact.

Hepatitis A outbreak in HIV-infected MSM and in PrEP-using MSM despite a high level of immunity, Lyon, France, January to June 2017

PubMed Central

Charre, Caroline; Ramière, Christophe; Roque-Afonso, Anne-Marie; Chidiac, Christian; Zoulim, Fabien; Godinot, Matthieu; Koffi, Joseph; Scholtès, Caroline; Livrozet, Jean-Michel; Cotte, Laurent

2017-01-01

Since 2016, an increase in the number of hepatitis A cases affecting mainly men who have sex with men (MSM) has been reported in low endemic countries in Europe. We calculated the attack rate in Lyon, France, in populations considered at high-risk: HIV-infected MSM and HIV-negative MSM receiving HIV pre-exposure prophylaxis (PrEP). In these populations, high level of immunity did not prevent the outbreak, indicating that vaccination should be reinforced, particularly in younger individuals. PMID:29208161

Sokolow-Lyon voltage is suitable for monitoring improvement in cardiac function and prognosis of patients with idiopathic dilated cardiomyopathy.

PubMed

Fukaya, Kenji; Takeshita, Kyosuke; Okumura, Takahiro; Hiraiwa, Hiroaki; Aoki, Soichiro; Ichii, Takeo; Sugiura, Yuki; Kitagawa, Katsuhide; Kondo, Toru; Watanabe, Naoki; Kano, Naoaki; Furusawa, Kenji; Sawamura, Akinori; Morimoto, Ryota; Bando, Yasuko; Murohara, Toyoaki

2017-09-01

The clinical significance of electrocardiogram in the assessment of patients with idiopathic dilated cardiomyopathy (IDCM) is currently unknown. The aim of this study was to determine the feasibility of recording serial changes in Sokolow-Lyon voltage (∆%QRS-voltage) in one year to estimate left ventricular reverse remodeling (LVRR) and predict a prognosis of IDCM patients under tailored medical therapy. Sixty-eight consecutive patients with mild symptoms (52.1 ± 13 years old; 69% men; NYHA I/II/III/IV; 33/29/6/0) underwent electrocardiography and echocardiography at baseline and 12 month follow-up (follow-up period: 3.9 years). LVRR was observed in 30 patients (44.1%). The ∆%QRS-voltage was significantly lower in the LVRR group (LVRR; -26.9%, non-LVRR: -9.2%, p < .001). Univariate analysis showed that ∆%QRS-voltage correlated with ∆%LV end-diastolic diameter (r = .634, p < .001), and with ∆%LV ejection fraction and ∆%LV mass index (r = -.412, p < .001; r = .429, p < .001 respectively). Using receiver operating characteristic curve analysis for the estimation of LVRR, ∆%QRS of -14.7% showed optimal sensitivity (63.2%) and specificity (83.3%) (AUC = 0.775, p < .001). The composite endpoints of cardiac death (n = 0), hospitalization for advanced heart failure (n = 11) and fatal arrhythmia (n = 2) were observed in 13 patients during the follow-up period. Kaplan-Meier analysis showed significantly higher event-free rate in patients of the low ∆%QRS-voltage group (<-14.7%) (83%) than those of the high group (66%, p = .022). The present study showed that decrease in Sokolow-Lyon voltage is associated with improvement in cardiac function and favorable prognosis in IDCM patients on medical therapy, suggesting that this index is a feasible marker for response to treatment of IDCM. © 2017 Wiley Periodicals, Inc.

Consumption of psychoactive substances among 535 women entering a Lyon prison (France) between June 2004 and December 2008.

PubMed

Sahajian, F; Lamothe, P; Fabry, J; Vanhems, P

2012-10-01

In France, recent data on the consumption of psychoactive substances (PASs) among women entering prison are virtually nonexistent. The objective of this study was to describe the characteristics of female entrants at Montluc prison in Lyon (France) and to estimate their PAS consumption. Between June 1, 2004 and December 31, 2008, of 841 women entering the Lyon correctional facility, 535 had an entrance interview, conducted by a nurse, during which a questionnaire was systematically proposed; 306 detainees did not have this interview and could not be included in the study because of an immediate transfer to another prison or emergency hospitalization. Socioeconomic and incarceration characteristics, PAS consumption, as well as consumption level (occasional, regular, abusive or dependence) and psychological distress of the 535 interviewed detainees were systematically noted. This psychological distress was defined by the presence in the entrant talks or behavior suggesting clinical symptoms such as anxiety, depression, delusion, delirium, and mood or behavior disorders. Descriptive analysis was undertaken with the Chi(2) test and Fisher's exact test for differences between the proportions observed. The average age of the 534 responding detainees was 31.5 years; 59.2% had had no ongoing professional activity in the 12 months prior to incarceration, and 21.6% had already been imprisoned before; 37.5% of the entrants reported dependence on tobacco and 13.7% on alcohol; 6.6% reported regular, abusive use or dependence on cannabis, 20.4% on psychotropic medications, and 7.7% on other drugs (heroin, cocaine, synthetic drugs) in the 6 months preceding their incarceration; 39.2% of the consumers at risk reported using at least two substances; 7.1% of detainees were on opioid substitution treatment. A multiple correspondence factor analysis was used to note specific characteristics of three groups of PAS consumers. More frequent among young women detainees, overall PAS

Programme and Abstracts. Workshop on Expert Evaluation and Control of Compound Semiconductor Materials and Technologies (1st) Held in Ecole Centrale De Lyon, France on 19 -22 May 1992. (EXAMTEC’ 92)

DTIC Science & Technology

1992-05-22

Evaluation and Control of Compound Semiconductor Materials and Technologies (EXMATEC󈨠) at Ecole Centrale de Lyon (Ecully, France, 19th to 22nd May...semiconductor technologies to manufacture advanced devices with improved reproducibility, better reliability and lower cost. -’Device structures...concepts are required for expert evaluation and control of still developing technologies . In this context, the EXMATEC series will constitute a major

[The first anti-cancer center in Lyon (1923): surgeon Leon Berard and Auguste Lumiere].

PubMed

Fischer, L P; Martinet, B; Glas, P Y

2001-01-01

At present, little is known about the creation of cancer hospitals. I will report on that of Lyons, France, with the famous surgeon, Léon Bérard (1870-1956). A specialist of neck surgery, he was the first to carry out major thoracoplasties. The cancer hospital was inaugurated in 1923 under the Great Dome of the hôtel-Dieu hospital. (The dome is the creation of the famous architect Germain Soufflot (1748)). In 1933, the cancer hospital moved in the newly-built Edouard Herriot Hospital; it became independent in 1958, two years after the famous surgeon's death, and it was rightly named after him: "Centre anticancéreux Léon Bérard". Its creation and its quick development owes a lot to generosity of Auguste Lumière, one of the two inventors of cinematograph. Auguste Lumière sponsored radiotherapy material and, at Léon Bérard's request (as there was a lack of space in Edouard Herriot hospital), created a centre for cancer patients (Bon Abr Hospital, rue Mistral, with Dr Vigne). A Lumière gave his time as well as his money for the centre; he was the car-driver, he helped L. Bérard with his university classes, and he often comforted the patients while running a private clinic (La Clinique Lumière), which combined dispensary services with research. (Micheline Bonin)

Open IoT Ecosystem for Enhanced Interoperability in Smart Cities-Example of Métropole De Lyon.

PubMed

Robert, Jérémy; Kubler, Sylvain; Kolbe, Niklas; Cerioni, Alessandro; Gastaud, Emmanuel; Främling, Kary

2017-12-08

The Internet of Things (IoT) has promised a future where everything gets connected. Unfortunately, building a single global ecosystem of Things that communicate with each other seamlessly is virtually impossible today. The reason is that the IoT is essentially a collection of isolated "Intranets of Things", also referred to as "vertical silos", which cannot easily and efficiently interact with each other. Smart cities are perhaps the most striking examples of this problem since they comprise a wide range of stakeholders and service providers who must work together, including urban planners, financial organisations, public and private service providers, telecommunication providers, industries, citizens, and so forth. Within this context, the contribution of this paper is threefold: (i) discuss business and technological implications as well as challenges of creating successful open innovation ecosystems, (ii) present the technological building blocks underlying an IoT ecosystem developed in the framework of the EU Horizon 2020 programme, (iii) present a smart city pilot (Heat Wave Mitigation in Métropole de Lyon ) for which the proposed ecosystem significantly contributes to improving interoperability between a number of system components, and reducing regulatory barriers for joint service co-creation practices.

Open IoT Ecosystem for Enhanced Interoperability in Smart Cities—Example of Métropole De Lyon

PubMed Central

Robert, Jérémy; Kolbe, Niklas; Cerioni, Alessandro; Gastaud, Emmanuel

2017-01-01

The Internet of Things (IoT) has promised a future where everything gets connected. Unfortunately, building a single global ecosystem of Things that communicate with each other seamlessly is virtually impossible today. The reason is that the IoT is essentially a collection of isolated “Intranets of Things”, also referred to as “vertical silos”, which cannot easily and efficiently interact with each other. Smart cities are perhaps the most striking examples of this problem since they comprise a wide range of stakeholders and service providers who must work together, including urban planners, financial organisations, public and private service providers, telecommunication providers, industries, citizens, and so forth. Within this context, the contribution of this paper is threefold: (i) discuss business and technological implications as well as challenges of creating successful open innovation ecosystems, (ii) present the technological building blocks underlying an IoT ecosystem developed in the framework of the EU Horizon 2020 programme, (iii) present a smart city pilot (Heat Wave Mitigation in Métropole de Lyon) for which the proposed ecosystem significantly contributes to improving interoperability between a number of system components, and reducing regulatory barriers for joint service co-creation practices. PMID:29292719

[Renal denervation for treating hypertension: experience at the University Hospital in Lyon].

PubMed

Courand, P-Y; Dauphin, R; Rouvière, O; Paget, V; Khettab, F; Bergerot, C; Harbaoui, B; Bricca, G; Fauvel, J-P; Lantelme, P

2014-06-01

We report the first experience of Lyon's university hospital regarding renal denervation to treat patients with resistant essential hypertension. Over a one-year period, 17 patients were treated (12 men, 5 women) with renal denervation. Baseline characteristics were as follows: age 56.5±11.5 years, BMI 33±5kg/m(2) and ambulatory blood pressure 157±16/87±13mmHg with 4.2±1.5 anti-hypertensive treatment. We did not observe intra-operative or early complications. After a median follow-up of 3 months and with the same anti-hypertensive treatment, office systolic blood pressure (SBP) and diastolic blood pressure (DBP) decrease respectively of 20±15 (P<0.001) and 10±13mmHg (P=0.014) (n=17). After six months of follow-up, ambulatory blood pressure (ABPM) decrease of 17.5±14.9mmHg (P=0.027) for SBP and of 10.5±9.6mmHg (P=0.029) for DBP (n=6). Among these patients, five of them were controlled (ABPM inferior to 130/80mmHg) and electrical left ventricular hypertrophy indexes decreased: R wave in aVL lead of 4±3mm (P=0.031), Sokolow index of 3±3mm (P=0.205), Cornell voltage criterion of 9±7mm (P=0.027) and Cornell product of 1310±1104 (P=0.027). Our results are in accordance with data from other centers. On average blood pressure decreases significantly but important inter individual variations are observed. The procedure seems safe. Copyright © 2014. Published by Elsevier SAS.

Short term effects of air pollution on mortality in the city of Lyon, France, 1985-90.

PubMed Central

Zmirou, D; Barumandzadeh, T; Balducci, F; Ritter, P; Laham, G; Ghilardi, J P

1996-01-01

OBJECTIVE: The short term association between daily mortality and ambient air pollution in the city of Lyon, France (population, 410,000) between 1985 and 1990 was assessed using time series analysis. DESIGN: This study followed the standardised design and statistical analysis (Poisson regression) that characterise the APHEA project. METHODS: Four categories of cause of death were studied: total (minus external causes), respiratory, cardiovascular, and digestive causes (as a control condition). RESULTS: No association was found with any cause of death for nitrogen dioxide (NO2) and ozone (O3), nor, for any pollutant, for digestive conditions. Sulphur dioxide (SO2) and, to a much lesser degree, suspended particles (PM13), were significantly related to mortality from respiratory and cardiovascular conditions. The relative risk (RR) of respiratory deaths associated with a 50 micrograms/m3 increment of mean daily SO2 over the whole period was 1.22 (95% CI 1.05, 1.40); the RR for cardiovascular deaths was 1.54 (1.22, 1.96). The corresponding RRs for PM13 were 1.04 (1.00, 1.09) for respiratory mortality and 1.04 (0.99, 1.10) for cardiovascular deaths. CONCLUSIONS: The effects of particulates were slightly increased during the cold season. When particulates concentrations were greater than 60 micrograms/m3, the joint SO2 effect was increased, suggesting some interaction between the two pollution indicators. These results agree with other studies showing an association between particulate pollution and daily mortality; however, they also suggest the noxious effect of SO2. PMID:8758221

The Middle East and Eastern Europe rabies Expert Bureau (MEEREB) third meeting: Lyon-France (7-8 April, 2015).

PubMed

Picot, V; Rasuli, A; Abella-Rider, A; Saadatian-Elahi, M; Aikimbayev, A; Barkia, A; Benmaiz, S; Bouslama, Z; De Balogh, K; Dehove, A; Davlyatov, F; Farahtaj, F; Gongal, G; Gholami, A; Imnadze, P; Issad, M; Khoufi, S; Nedosekov, V; Rafila, A; Rich, H; Soufi, A; Tuychiev, J; Vranjes, N; Vodopija, R; Zaouia, I; Nel, L

MEEREB is an inter-regional network of countries from North Africa, Europe, the Middle East and Central Asia that work together with the aim of improving rabies control and prevention at local, regional and global level. MEEREB members met for the third time in 2015 in France (Lyon) to review the current rabies situation within the network and to discuss the way forward the prospect of a One Health approach against rabies. Dogs were the main vector of transmission in all MEEREB countries except for Croatia and Serbia where foxes represented the primary source. The number of rabies animal cases reported in 2014 varied substantially between countries with Ukraine reporting the highest number of animal cases. Human cases still occur in North Africa and all Middle East and Eurasian countries while no cases of human rabies were reported in Croatia, Serbia and Romania, although cases of rabies were identified in both dogs and foxes in 2014. Participants concluded that MEEREB can act as a think-tank where countries can share data, information, experiences and best practices to jointly address challenges in rabies control and prevention. They called for elimination of dog-transmitted rabies through vaccine and rabies immunoglobulin stockpiles and implementation of a One Health approach to achieve rabies's eradication. Copyright © 2017 The Authors. Published by Elsevier Ltd.. All rights reserved.

Occurrence of betablockers in effluents of wastewater treatment plants from the Lyon area (France) and risk assessment for the downstream rivers.

PubMed

Miège, Cécile; Favier, Maxime; Brosse, Corinne; Canler, Jean-Pierre; Coquery, Marina

2006-11-15

Five betablockers (oxprenolol, metoprolol, propranolol, bisoprolol, betaxolol) were analysed in effluents collected over a 3-month period from wastewater treatment plants (WTP) from the Lyon area in France. The analytical protocol consisted of solid phase extraction of the dissolved aqueous phase on HLB cartridges and analysis by gas chromatography coupled with mass detection (GC-MS) after derivatization. Concentrations of metoprolol, propranolol and bisoprolol varied from 45 to 2838ng/L whereas oxprenolol and betaxolol were never detected in these effluent samples. A high variability of betablockers concentrations and fluxes was observed between WTP effluents and within each WTP over the time period studied. Considering a flux per person for a dry weather period, Fontaine plant was pointed out as the less efficient WTP, which might be explained by its type of treatment (biological aerated filters). But we need additional analysis of effluent and influent waters to confirm this hypothesis. A tentative approach of local environmental risk assessment of propranolol based on the calculation of PEC/PNEC (predicted environmental concentration/predicted non effect concentration) ratio approach lead us to conclude on a negligible risk for the downstream rivers (Rhône river at Ternay and Saône river at Couzon Mt d'Or).

Bedrock Geologic Map of New Hampshire, a Digital Representation of Lyons and Others 1997 Map and Ancillary Files

USGS Publications Warehouse

Bennett, Derek S.; Lyons, John B.; Wittkop, Chad A.; Dicken, Connie L.

2006-01-01

The New Hampshire Geological Survey collects data and performs research on the land, mineral, and water resources of the State, and disseminates the findings of such research to the public through maps, reports, and other publications. The Bedrock Geologic Map of New Hampshire, by John B. Lyons, Wallace A. Bothner, Robert H. Moench, and James B. Thompson, was published in paper format by the U.S. Geological Survey (USGS) in 1997. The online version of this CD contains digital datasets of the State map that are intended to assist the professional geologist, land-use planners, water resource professionals, and engineers and to inform the interested layperson. In addition to the bedrock geology, the datasets include geopolitical and hydrologic information, such as political boundaries, quadrangle boundaries, hydrologic units, and water-well data. A more thorough explanation for each of these datasets may be found in the accompanying metadata files. The data are spatially referenced and may be used in a geographic information system (GIS). ArcExplorer, the Environmental Systems Research Institute's (ESRI) free GIS data viewer, is available at http://www.esri.com/software/arcexplorer. ArcExplorer provides basic functions that are needed to harness the power and versatility of the spatial datasets. Additional information on the viewer and other ESRI products may be found on the ArcExplorer website. Although extensive review and revisions of the data have been performed by the USGS and the New Hampshire Geological Survey, these data represent interpretations made by professional geologists using the best available data, and are intended to provide general geologic information. Use of these data at scales larger than 1:250,000 will not provide greater accuracy. The data are not intended to replace site-specific or specific-use investigations. The U.S. Geological Survey, New Hampshire Geological Survey, and State of New Hampshire make no representation or warranty

Functional electrical stimulation cycling strategies tested during preparation for the First Cybathlon Competition – a practical report from team ENS de Lyon

PubMed Central

Metani, Amine; Popović-Maneski, Lana; Mateo, Sebastien; Lemahieu, Laura; Bergeron, Vance

2017-01-01

Whether it is from the patient’s or the physical therapist’s point of view, FES cycling can be considered either as a recreational activity, or an engaging rehabilitation tool. In both cases, it keeps patients with lower-limb paralysis motivated to sustain a regular physical activity. Thus, it is not surprising that it was selected as one of the six disciplines of the first Cybathlon competition held on October 8, 2016. However, many unresolved issues prevent FES cycling from being an activity practiced outdoors on a daily basis; such as, low power production, rapid muscle fatigue, precise electrode positioning, lack of systematic procedures to determine stimulation patterns, and the difficulty of transferring disabled riders from their wheelchair to the tricycle. This article documents the challenges we faced during preparation for the Cybathlon 2016 FES cycling race, and provides results obtained during different phases of the process. A particular specificity of our team was that, unlike most other teams where pilots were mainly paraplegic, both the primary and backup pilots for team ENS de Lyon are C6/C7 tetraplegics, with neither voluntary control of their abdominal muscles nor hand grip, and only partial use of their arms. PMID:29299222

French Research in Acoustics and Signal Processing: Report on Introductory Visit

DTIC Science & Technology

1986-05-01

CEPHAG (Centre d’Etude des Phenomenes Aleatoires et Geophysiques ), which is associated with the Institut National Polytechnique at Grenoble. We were...measurement programs. Centre d’Etude des Phenomenes Aleatoires et Geophysiques (CEPHAG), Institut National Polytechnique, Universite de Grenoble, 23 May...69288 Lyon Cedex, France, Tel 72.32.50.67. CENTRE D’ETUDE DES PHENOMENES ALEATOIRES ET GEOPHYSIQUES (CEPHAG), Grenoble. Prof. J. L. Lacoume

[The impact of the data collection method on the medico-economic classification of admissions for myocardial infarction at the public hospitals in Lyon].

PubMed

Rabilloud, M; Ecochard, R; Myard, A F; Delahaye, F; Colin, C; Matillon, Y

1998-06-01

The aim of the PMSI (Programme de Médicalisation du Système d'Information) is to describe the activity of hospitals for budget allocation. To control the quality of this information, the authors carried out a study comparing the classification in homogenous disease groups (HDG) obtained from the PMSI with that obtained from the epidemiological data base of the PRIMA trial for patients admitted to the Civil Hospitals of Lyon for myocardial infarction between September 1st 1993 and January 31st 1995. Six hundred and fifty standardised hospital summaries were reconstituted form PRIMA data and grouped using the GENRSA 3 software. Five hundred and forty-one of these hospital stays were found in the PMSI data base and grouped. The concordance not due to chance between the two classifications was then assessed by the global kappa coefficient. It was less than the 40% threshold under which concordance not due to chance is considered to be unlikely. The discordances were essentially due to the presence of an associated diagnosis classifying the hospital stay in the HDG corresponding to complicated myocardial infarction. The presence of a classifying associated diagnosis was observed significantly more often in the PRIMA than in the PMSI data base. This results in an underestimation of the hospital activity and could have important repercussions in terms of budget allocation.

[A Lumière's pharmacist: Marius Sestier (1861-1928)].

PubMed

Raynal, Cécile

2010-04-01

During the year 1896 Marius Sestier, the young pharmacist from the french city Lyon, becomes cinematograph operator for the Lumière brothers. Sent in Australia to use the recent invention, he must come back in France after only one year in the southern hemisphere. In Lyon, he remains in Lumière's service but becomes pharmacist again. He's employed as the responsible pharmacist of the new society created by Auguste Lumière: "la Société des Produits chimiques spéciaux "Brevets Lumière". This essay relates Sestier's biography and, concurrently, several drugs, foundation and development of those laboratories wich are well known as "Laboratoires Lumière".

Water-quality assessment of the Frank Lyon, Jr., nursery pond releases into Lake Maumelle, Arkansas, 1991-1996

USGS Publications Warehouse

Green, William Reed

1998-01-01

Releases of the Frank Lyon, Jr., Nursery Pond into Lake Maumelle were monitored during 1991 through 1996 to assess the impact that the releases have on the water quality of Lake Maumelle. Results indicated that the water-quality impact of the nursery pond release into Lake Maumelle is variable, and appears to be related to the volume of the nursery pond at release and the amount of fertilizer applied within the nursery pond earlier in the year. In 1991 through 1994 and in 1996, nursery pond release loads for nutrients (except for dissolved nitrite plus nitrate nitrogen), total and dissolved organic carbon, iron, and manganese were greater than what would be expected in the annual area load from that basin. In 1995, only ammonium nitrate was appliec to the nursery pond. As a result, the 1995 phosphorus load was lower than in other years, and was less than what would be expected in the annual areal load. Nutrient enrichment, on average, in Lake Maumelle from the nursery pond release resulted in what would be equivalent to an 8 percent increase in concentration of total phosphorus, 50 percent increase in dissolved orthophosphorus, 0.1 percent increase in dissolved nitrite plus nitrate nitrogen, 2.5 percent increase in total ammonia plus organic nitrogen, and 5.7 percent increase in dissolved ammonia nitrogen, assuming that the nutrient load was conservative and evenly distributed throughout the water body. Evidence of elevated turbidity, nutrient, and chlorphyll a concentrations in the epilimnetic water outside the receiving embayment were apparent for as long as 3 weeks after the 1995 and 1996 releases. In general, highest values were found at the site located where the receiving embayment meets the open water of Lake Maumelle. Much of the released material in the nursery pond originated in the cooler, anoxic hypolimnetic water. The initial release water was seen to plunge beneath the warmer water existing in the receiving embayment and was transported into the open

Evaluation of recharge to the Skunk Creek Aquifer from a constructed wetland near Lyons, South Dakota

USGS Publications Warehouse

Thompson, Ryan F.

2002-01-01

A wetland was constructed in the Skunk Creek flood plain near Lyons in southeast South Dakota to mitigate for wetland areas that were filled during construction of a municipal golf course for the city of Sioux Falls. A water-rights permit was obtained to allow the city to pump water from Skunk Creek into the wetland during times when the wetland would be dry. The amount of water seeping through the wetland and recharging the underlying Skunk Creek aquifer was not known. The U.S. Geological Survey, in cooperation with the city of Sioux Falls, conducted a study during 1997-2000 to evaluate recharge to the Skunk Creek aquifer from the constructed wetland. Three methods were used to estimate recharge from the wetland to the aquifer: (1) analysis of the rate of water-level decline during periods of no inflow; (2) flow-net analysis; and (3) analysis of the hydrologic budget. The hydrologic budget also was used to evaluate the efficiency of recharge from the wetland to the aquifer. Recharge rates estimated by analysis of shut-off events ranged from 0.21 to 0.82 foot per day, but these estimates may be influenced by possible errors in volume calculations. Recharge rates determined by flow-net analysis were calculated using selected values of hydraulic conductivity and ranged from 566,000 gallons per day using a hydraulic conductivity of 0.5 foot per day to 1,684,000 gallons per day using a hydraulic conductivity of 1.0 foot per day. Recharge rates from the hydrologic budget varied from 0.74 to 0.85 foot per day, and averaged 0.79 foot per day. The amount of water lost to evapotranspiration at the study wetland is very small compared to the amount of water seeping from the wetland into the aquifer. Based on the hydrologic budget, the average recharge efficiency was estimated as 97.9 percent, which indicates that recharging the Skunk Creek aquifer by pumping water into the study wetland is highly efficient. Because the Skunk Creek aquifer is composed of sand and gravel, the

Processes in Organizational Change

DTIC Science & Technology

1987-06-01

Gadon, 1978; S- Pierce & Newstrom, 1980; Ronen, 1981) a I a numbe-" of field experiments have found their way into the literature ( Ivancevich & Lyon ... Ivancevich and Lyon , 1977) found no long-run evidence of an impact on performance. Evidence concerninq the impact of flexible schedules on...often associated with compressed work schedules (Goodale & Aagaard, 1975; Hedges, L971; Hodge & Tellier, 1975; Ivancevich , 1974; Ivancevich & Lyon , 1977

Assessment of fluxes of priority pollutants in stormwater discharges in two urban catchments in Lyon, France

NASA Astrophysics Data System (ADS)

Becouze, C.; Bertrand-Krajewski, J. L.; Coquery, M.; Dembélé, A.; Cren-Olivé, C.

2009-04-01

Keywords: WFD, priority pollutants, stormwater, sewer systems, atmospheric deposition The European Water Framework Directive (WFD, 2000) requires both a progressive reduction of priority substances discharges and a cessation of hazardous priority substances discharges into water bodies. In order to define priorities for action in a global and integrated urban water management approach, we need to identify and quantify all sources of pollutants (diffuse agricultural and urban emissions, industrial emissions, effluents from wastewater treatment plants, from separate and combined sewer systems, etc.). The objectives of the ESPRIT collaborative project are to identify, evaluate, characterise and later on model the fluxes of priority substances in urban stormwater, for both combined and separate sewer systems. This paper presents i) the methodology applied to collect representative samples of dry atmospheric deposits, of rainwater and of stormwater discharges at the outlet of experimental catchments, ii) the EMC (Event Mean Concentrations) values and the fluxes of 36 organic substances and of 26 metals calculated for various storm events, and iii) the discussion of these results. Two experimental sites have been selected in Lyon for the project: Ecully (combined sewer system draining a 245 ha residential catchment) and Chassieu (separate stormwater system draining a 185 ha industrial catchment). Each catchment outlet is equipped with sensors measuring various parameters (flow depth and velocity, pH, conductivity, turbidity, temperature) and with refrigerated automatic samplers. Each site is also equipped with prototype devices collecting separately samples of both dry atmospheric deposits and rainwater. All sampling devices comply with requirements for trace micro-pollutants monitoring (Teflon tubing, clean glass bottles, etc.). Field and laboratory blank procedures were carried out to quantify the possible contamination along the sampling/conditioning chain. Event mean

Environmental and Water Quality Operational Studies. Environmental Features for Streamside Levee Projects.

DTIC Science & Technology

1985-08-01

Lyon 1976, Lyon and Basile 1979, Lyon and Jenson 1980) showed that windrows over 1.5 ft tall are avoided by mule deer and elk. Thus, brush piles...various State pesticide control authorities. Label directions and general regulations promulgated by these agencies have the power of law and should be...matters, relative attractiveness of alternative baits can vary with season. 606. Like other pesticides , rodenticides are strictly controlled 0 by

3. Historic American Buildings Survey E. W. Russell, Photographer, September ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

3. Historic American Buildings Survey E. W. Russell, Photographer, September 1, 1936 STEPS AND RAILINGS, LYONS HOME - 300 STATE STREET - Patrick Lyons House (Ironwork), 300 State Street, Mobile, Mobile County, AL

The oncologic outcome and immediate surgical complications of lipofilling in breast cancer patients: a multicenter study--Milan-Paris-Lyon experience of 646 lipofilling procedures.

PubMed

Petit, Jean Yves; Lohsiriwat, Visnu; Clough, Krishna B; Sarfati, Isabelle; Ihrai, Tarik; Rietjens, Mario; Veronesi, Paolo; Rossetto, Fabio; Scevola, Anna; Delay, Emmanuel

2011-08-01

Lipofilling is now performed to improve the breast contour, after both breast-conserving surgery and breast reconstruction. However, injection of fat into a previous tumor site may create a new environment for cancer and adjacent cells. There is also no international agreement regarding lipofilling after breast cancer treatment. The authors included three institutions specializing in both breast cancer treatment and breast reconstruction (European Institute of Oncology, Milan, Italy; Paris Breast Center, Paris, France; and Leon Berard Centre, Lyon, France) for a multicenter study. A collective chart review of all lipofilling procedures after breast cancer treatment was performed. From 2000 to 2010, the authors reviewed 646 lipofilling procedures from 513 patients. There were 370 mastectomy patients and 143 breast-conserving surgery patients. There were 405 patients (78.9 percent) with invasive carcinoma and 108 (21.1 percent) with carcinoma in situ. The average interval between oncologic surgical interventions and lipofilling was 39.7 months. Average follow-up after lipofilling was 19.2 months. The authors observed a complication rate of 2.8 percent (liponecrosis, 2.0 percent). Twelve radiologic images appeared after lipofilling in 119 breast-conserving surgery cases (10.1 percent). The overall oncologic event rate was 5.6 percent (3.6 percent per year). The locoregional event rate was 2.4 percent (1.5 percent per year). Lipofilling after breast cancer treatment leads to a low complication rate and does not affect radiologic follow-up after breast-conserving surgery. A prospective clinical registry including high-volume multicenter data with a long follow-up is warranted to demonstrate the oncologic safety. Until then, lipofilling should be performed in experienced hands, and a cautious oncologic follow-up protocol is advised. Therapeutic, IV [corrected].

1. Historic American Buildings Survey E. W. Russell, Photographer, September ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

1. Historic American Buildings Survey E. W. Russell, Photographer, September 1, 1936 FRONT ELEVATION, P. J. LYONS HOME - 300 STATE STREET - Patrick Lyons House (Ironwork), 300 State Street, Mobile, Mobile County, AL

2. Historic American Buildings Survey E. W. Russell, Photographer, September ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

2. Historic American Buildings Survey E. W. Russell, Photographer, September 1, 1936 STANDARD AND BRACKETS, P. J. LYONS HOME - 300 STATE STREET - Patrick Lyons House (Ironwork), 300 State Street, Mobile, Mobile County, AL

Differences in Perceptions of Organizational Conditions, Job Attitudes, and Health Beliefs Among Military Physicians, Dentists, and Nurses.

DTIC Science & Technology

1984-09-01

Bates and Moore, 1975; Leatt and Scheneck. 1980; Lyon and Ivancevich . 7...1970. Lyon . R. F. & Ivancevich • J. N. A behavioral study of nurses. supervisors, and diagnosticians in a hospital setting. Decision Sciences. 1978

Enhancing Productivity through Feedback and Goal Setting

DTIC Science & Technology

1981-07-01

accurate versus in- accurate (Griswold, 1970), information content (Berman, Fraser, & Theious, 1970), and frequency ( Ivancevich , Donnelly, & Lyon ...Applied Psychology, 1975, 60, 159-170. Ivancevich , J.M., Donnelly, J.N., & Lyon , J.L. A study of the impact of management by objectives on perceived

Supply and Demand: Religious Schooling in Ninteenth-Century France.

ERIC Educational Resources Information Center

Curtis, Sarah A.

1999-01-01

Examines the reasons behind the expansion of congregational primary education before the educational push of the Third Republic in the diocese of Lyon (France). Argues that the popularity of Catholic-sponsored schooling in Lyon depended on the conjuncture of religious philanthropy and cost effectiveness. (CMK)

Symptom Clusters and Work Limitations in Employed Breast Cancer Survivors

DTIC Science & Technology

2011-11-16

gliomas (Fox, Lyon, & Farace , 2007). Across studies of breast cancer patients, similar symptom clusters have emerged: researchers have identified...Symptom clusters and quality of life in survivors of lung cancer. Oncology Nursing Forum, 33(5), 931-936. Fox, S., Lyon, D., & Farace , E. (2007

Firefighting and Emergency Response Study of Advanced Composites Aircraft. Objective 4: Post Fire Decontamination of Personal Protection Equipment

DTIC Science & Technology

2011-11-01

correlating with the common use of graphite-epoxy composites in aerospace materials. Ghandi and Lyon identify two primary exposure routes from...Materials, Springer, Dordrecht, The Netherlands, 2006; Chapter 12, “Health Hazards of Composites in Fire”. 5. Sanjeev Ghandi and Richard E. Lyon, Health

Cultural Resource Investigations for the Lyons Ferry Fish Hatchery Project, Near Lyons Ferry, Washington.

DTIC Science & Technology

1983-01-01

Intermontane Plateau of Western North America. In The Explanation of Culture Change: Models in Prehistory, edited by Colin Renfrew, University of...site ( Drury 1958:257). 72 1841 Charles Wilkes, linguist and explorer, traveled from Whitman Mission to Fort Colvile by the site (Wilkes 1856 4:466...Parts of the Continent of North America during the Years 1824-󈧝-󈧞-󈧟. Oregon Historical Quarterly, 5(4):325-369, Portland. Drury , Clifford M

Predicting Faculty Integration of Faith and Learning

ERIC Educational Resources Information Center

Kaul, Corina R.; Hardin, Kimberly A.; Beaujean, A. Alexander

2017-01-01

Concern regarding the secularization of Christian higher education has prompted researchers to investigate the extent that faith and learning is integrated at a faculty level and what factors might predict faculty integration (Lyon, Beaty, Parker, & Mencken, 2005). This research attempted to replicate Lyon et al.'s (2005) logistic regression…

Hypercat: A Database for Extragalactic Astronomy

NASA Astrophysics Data System (ADS)

Prugniel, Ph.; Maubon, G.

The Hypercat Database is developed at Observatoire de Lyon and is distributed on the WEB(www-obs.univ-lyon1.fr/hypercat) through different mirrors in Europe. The goal of Hypercat is to gather data necessary for studying the evolution of galaxies (dynamics and stellar contains) and particularly for providing a z = 0 reference for these studies.

Apollo 17 celebration

NASA Image and Video Library

2012-12-07

Ariana Lyons from Escatawpa Elementary School in Moss Point, Miss., experiences what it feels like to view the world out of a spacesuit during a visit to INFINITY Science Center, a NASA visitors center, Dec. 7. Lyons joined other young visitors to the facility that day in celebrating the 40th anniversary of the Apollo 17 mission to the moon in 1972.

Stress in Organizations. A Review of the Literature

DTIC Science & Technology

1987-07-01

Lyons (1971), in which the variable role clarity (the converse of role ambiguity) correlated -.59 with job tension. An examination of the two scales...Matteson and Ivancevich (1979), in their review, admonished that management’s responsibility does not end with the obligation to improve...S., & Jensen, J. (1984). Stressful events, dysphoric mood, and immune responsiveness. Psychological Reports, 54, 219-222. Lyons , T. F. (1971

Feedback, Goal Setting, and Incentives Effects on Organizational Productivity.

DTIC Science & Technology

1987-06-01

frequency of feedback (Chobbar & Wallin, 1984; Ivancevich , Donnelly, & Lyon , 1970). Greller (1975) focused on the sources of feedback in organizations...of ApDlied Psychalody, 0(4), 349-371. Ivancevich , J.M., Donnelly, J.N., & Lyon , J.L. (1970). A study of the impact of management by objectives on...Dockstader, Nebeker, & Shumate, 1977; Ilgen, Fisher, & Taylor, 1979; Ivancevich & McMahon, 1982; Pnitchard, Bigby, Beiting, Coverdale, & Morgan, 1981

Molecular Simulation of the Vapor-Liquid Phase Behavior of Lennard-Jones Mixtures in Porous Solids

DTIC Science & Technology

2006-09-01

sur la Catalyse, Centre National de la Recherche Scientifique, Group de Chimie Theorique, 2 Avenue Albert Einstein, 69626 Villeurbanne Cedex, France...and Group de Chimie Theorique, Ecole Normale Superieure de Lyon, 46 Allee d’Italie, 69364 Lyon, Cedex 07, France 14. ABSTRACT We present vapor...Scientifique, Group de Chimie Theorique, 2 Avenue Albert Einstein, 69626 Villeurbanne Cedex, France and Group de Chimie Theorique, Ecole Normale

Underwater Cultural Resources Survey for Contraction Dikes at Red Eye Crossing, Mississippi River, Baton Rouge to the Gulf of Mexico, Louisiana

DTIC Science & Technology

1993-06-01

ojtala Edwin A. Lyon Te hnical Representative Authorized Representative of the Contracting Officer ______________________________Accesion For R. H... Edwin A. Lyon ably served as COR. Mr. James Woltala, Technical Representative, served as liaison and provided much needed Information relating to the...the Indian tribes encountered along the journey that the group was "the first Europeans who have descended or ascended the River Colbert [Mississippi

Monitoring and Evaluation of Yearling Fall Chinook Salmon (Oncorhynchus tshawytscha) Released from Acclimation Facilities Upstream of Lower Granite Dam; 2001 Annual Report.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rocklage, Stephen J.; Kellar, Dale S.

2005-07-01

The Nez Perce Tribe, in cooperation with the U.S. Fish and Wildlife Service and Washington Department of Fish and Wildlife, conducted monitoring and evaluation studies on Lyons Ferry Hatchery reared yearling fall Chinook salmon Oncorhynchus tshawytscha that were acclimated and released at three Fall Chinook Acclimation Project sites upstream of Lower Granite Dam along with yearlings released on-station from Lyons Ferry Hatchery in 2001. This was the sixth year of a long-term project to supplement natural spawning populations of Snake River stock fall Chinook salmon upstream of Lower Granite Dam. The 318,932 yearlings released from the Fall Chinook Acclimation Projectmore » facilities were short of the 450,000 fish quota. We use Passive Integrated Transponder (PIT) tag technology to monitor the primary performance measures of survival to mainstem dams and migration timing. We also monitor size, condition and tag/mark retention at release. We released 7,503 PIT tagged yearlings from Pittsburg Landing, 7,499 from Big Canyon and 2,518 from Captain John Rapids. The Washington Department of Fish and Wildlife released 991 PIT tagged yearlings from Lyons Ferry Hatchery. Fish health sampling indicated that, overall, bacterial kidney disease levels could be considered relatively low. Compared to prior years, Quantitative Health Assessment Indices were relatively low at Big Canyon and Captain John Rapids and about average at Pittsburg Landing and Lyons Ferry Hatchery. Mean fork lengths (95% confidence interval) of the PIT tagged groups ranged from 155.4 mm (154.7-156.1 mm) at Captain John Rapids to 171.6 mm (170.7-172.5 mm) at Lyons Ferry Hatchery. Mean condition factors ranged from 1.02 at Lyons Ferry Hatchery to 1.16 at Big Canyon and Captain John Rapids. Estimated survival (95% confidence interval) of PIT tagged yearlings from release to Lower Granite Dam ranged from 74.4% (73.2-75.5%) for Big Canyon to 85.2% (83.5-87.0%) for Captain John Rapids. Estimated survival from

The Effects of Personality and Simulated Negotiation on Negotiation Effectiveness

DTIC Science & Technology

1978-12-01

A THE GALVANOMETER CASE ROLE of LARRY LYON , DIRECTOR OF MARKETING, SPARK ELECTRONICS CO. Your company manufactures, among other major products, galva...weighted guide- lines. Thus, with your negotiation position clearly in mind, you await the arrival of Larry Lyon , Director of Marketing, Spark Elec- A...E. T. Paine, and J. J. Ivancevich , "The Relative Effectiveness of Training Methods -- Expert Opinion and Research," Personnel Psychology, Autumn

A Test of the Theory of Reasoned Action at the Group Level of Analysis

DTIC Science & Technology

1993-09-01

Ivancevich , and Donnelly ,1991). Attitudes are determinants of behavior because they are connected to different parts of a person’s personality...1964 ; Locke, 1968; Lyons , 1971; Porter and Steers, 1973). However, the mass of turnover research did not occur until after 1974, partly due to...Rand McNally. 38 Lyne, G. (1989, December). How to measure employee attitudes, Training and Development Journal, 40-43. Lyons , T. (1971). Role clarity

An Analysis of Factors Related to Retirement Intentions of Upper Level Civil Service Employees in the Air Force.

DTIC Science & Technology

1986-09-01

workforce that is incapable of performing organizational objectives (Humple and Lyons , 1983; Tucker, 1985). . Research into retirement within the federal...organization (Donnelly, Gibson, Ivancevich ; 1984). The present study focuses on civilian middle managers, GM13 to GMI5, within technical career fields...Masson, Demestree, and Lyon ; 1979). The second study performed a factorial analysis on data from 457 respondents between the ages of 25 to 64 that worked

Collaborative Investigations of Shallow Water Optics Problems

DTIC Science & Technology

2004-12-01

Appendix E. Reprint of Radiative transfer equation inversion: Theory and shape factor models for retrieval of oceanic inherent optical properties, by F ...4829-4834. 5 Hoge, F . E., P. E. Lyon, C. D. Mobley, and L. K. Sundman, 2003. Radiative transfer equation inversion: Theory and shape factor models for...multilinear regression algorithms for the inversion of synthetic ocean colour spectra,, Int. J. Remote Sensing, 25(21), 4829-4834. Hoge, F . E., P. E. Lyon

Industrial Simulation Games for Executive Development: Review of the Literature and Implications for Military Applications

DTIC Science & Technology

1988-12-01

the effects of two formal training methods in the retail sales arena was reported by Ivancevich and Smith (1981). The methods involved (a) role...now established and that his work has extended the theory. Oligopoly theory also was the focus of the work reported by Lyons (1982). Oligopoly refers...benefit for the group while providing a fair share for each group member. Lyons described a computer-based game designed primarily for management

A Meta-Analysis of the Correlates of Role Conflict and Ambiguity.

DTIC Science & Technology

1982-05-01

Lyons , 1971; Stead and Scamell, 198; Ivancevich and Donnelly, 1974), tenure (Brief, Aldag, Van Sell, Melone,. 1979), higher order need strength (Beehr...JourDnal o _ ft is Psucholoau. 1965, 4 24-33. Lyons .. T.F. Role clarity, need for clarity, satisfaction, tension, * and withdrawal. Oranizational Behavior...82. Ivancevich , J.M. and Donnelly, J.H., Jr. A study of role clarity and need for clarity for three occupational groups. Academ af jt journal. 1974

Aviator Selection 1919-1977.

DTIC Science & Technology

1977-10-04

Evaluations of the link trainer by Page & Lyon (108), and Poe 8 Lyon (112), an approach landing trainer by Creelman (30) , and an aircraft trimming device by...similar results in research of the predictive value of gross muscular tasks by Creelman (29), and Schwarts and Lowe (117). However, study efforts by...and Training Research Center, Lackland AFB, Texas, 1957. 29. Creelman , J. A. An Analysis of the Physical Fitness Index in relation to training criteria

Spatial and temporal trends in PCBs in sediment along the lower Rhone River, France

USGS Publications Warehouse

Desmet, Marc; Mourier, Brice; Mahler, Barbara J.; Van Metre, Peter C.; Roux, Gwenaelle; Persat, Henri; Lefevre, Irene; Peretti, Annie; Chapron, Emmanuel; Anaelle, Simonneau; Miege, Cecile; Babut, Marc

2012-01-01

Despite increasingly strict control of polychlorinated biphenyl (PCB) releases in France since the mid-1970s, PCB contamination of fish recently has emerged as a major concern in the lower Rhone River basin. We measured PCB concentrations in Rhone sediment to evaluate the effects of PCB releases from major urban and industrial areas, sediment redistribution by large floods, and regulatory controls on PCB trends from 1970 to present. Profiles of PCBs (the sum of seven indicator PCB congeners) were reconstructed from sediment cores collected from an off-river rural reference site and from three depositional areas along the Rhone upstream and downstream from the city of Lyon, France. Core chronology was determined from radionuclide profiles and flood deposits. PCB concentrations increased progressively in the downstream direction, and reached a maximum concentration in 1991 of 281 μg/kg at the most downstream site. At the rural reference site and at the upstream Rhone site, PCB concentrations peaked in the 1970s (maximum concentration of 13 and 78 μg/kg, respectively) and have decreased exponentially since then. PCB concentrations in the middle and downstream cores were elevated into the early 1990s, decreased very rapidly until 2000, and since then have remained relatively stable. Congener profiles for three time windows (1965–80, 1986–93, and 2000–08) were similar in the three sediment cores from the Rhone and different from those at the rural reference site. The results indicate that permitted discharges from a hazardous-waste treatment facility upstream from Lyon might have contributed to high concentrations into the 1980-90s, but that industrial discharges from the greater Lyon area and tributaries to the Rhone near Lyon have had a greater contribution since the 1990s. There is little indication that PCB concentration in sediments downstream from Lyon will decrease over at least the short term.

Sleep and dream habits in a sample of French college students who report no sleep disorders.

PubMed

Vallat, Raphael; Eskinazi, Mickael; Nicolas, Alain; Ruby, Perrine

2018-02-06

There is a lack of up-to-date data on sleep and dream habits of college students. To fill in this gap, we used an online questionnaire sent to the student mailing lists of two major universities of Lyon (Lyon 1 and Lyon 2) for the recruitment of an functional magnetic resonance imaging study with sleep disorders as exclusion criteria. In the sample (1,137 French college students, 411 males, mean age = 22.2 ± 2.4 years, body mass index = 22.0 ± 3.2 kg m -2 ), on average, the participants reported spending about 8 hr in bed during weekdays, 9 hr during the weekends, and 90.9% of them reported no difficulty falling asleep. Less than 0.4% of students reported to have sleep-walking episodes regularly, but nearly 7% reported regular sleep-talking episodes. The average dream recall frequency was about 3 mornings per week with a dream in mind. Dream recall frequency was positively correlated with the clarity of dream content and the frequency of lucid dreaming, and was negatively correlated with age. Fourteen percent of the students reported frequent lucid dreams, and 6% reported frequent recurrent dreams. We found a gender effect for several sleep and dream parameters, including dream recall frequency and time in bed, both of which were higher in women than in men. We have also observed differences between academic disciplines, namely humanities students (Lyon 2) reported spending more time in bed than sciences students (Lyon 1). These results confirm a gender difference for several sleep and dream parameters, and suggest a link between academic disciplines and sleep duration. © 2018 European Sleep Research Society.

Measurement of infiltration rates in urban sewer systems by use of oxygen isotopes.

PubMed

De Bénédittis, J; Bertrand-Krajewski, J L

2005-01-01

The paper presents the principle of a method to measure infiltration rates in sewer systems based on the use of oxygen isotopes and its application in Lyon (France). In the urban area of Lyon, significant differences in delta 18O that can reach 3 per thousand are observed between the oxygen isotopic compositions of groundwater originating from Rhone, Saone and from their associated alluvial aquifers. Drinking water supplying Lyon results mainly from pumping in the Rhone alluvial aquifer. Therefore, in some areas, the difference of isotopic composition between wastewater resulting from the consumption of drinking water and local groundwater can be used to measure infiltration in sewer systems. The application in the catchment of Ecully shows that the infiltration flow rate presents strong fluctuations at an hourly scale: it varies between 15 and 40 m3/h. This variability could be explained by non-constant discharges of pumping and by variations of the water level in the sewer.

Monitoring and Evaluation of Yearling Fall Chinook Salmon (Oncorhynchus tshawytscha) Released from Acclimation Facilities Upstream of Lower Granite Dam; 2000 Annual Report.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rocklage, Stephen J.; Kellar, Dale S.

2005-07-01

The Nez Perce Tribe, in cooperation with the U.S. Fish and Wildlife Service and Washington Department of Fish and Wildlife, conducted monitoring and evaluation studies on Lyons Ferry Hatchery reared yearling fall Chinook salmon Oncorhynchus tshawytscha that were acclimated and released at three Fall Chinook Acclimation Project sites upstream of Lower Granite Dam along with yearlings released on-station from Lyons Ferry Hatchery in 2000. This was the fifth year of a long-term project to supplement natural spawning populations of Snake River stock fall Chinook salmon upstream of Lower Granite Dam. The 397,339 yearlings released from the Fall Chinook Acclimation Projectmore » facilities were short of the 450,000 fish quota. We use Passive Integrated Transponder (PIT) tag technology to monitor the primary performance measures of survival to mainstem dams and migration timing. We also monitor size, condition and tag/mark retention at release. We released 7,477 PIT tagged yearlings from Pittsburg Landing, 7,421 from Big Canyon and 2,488 from Captain John Rapids. The Washington Department of Fish and Wildlife released 980 PIT tagged yearlings from Lyons Ferry Hatchery. Fish health sampling indicated that, overall, bacterial kidney disease levels could be considered relatively low. Compared to prior years, Quantitative Health Assessment Indices were relatively low at Big Canyon and Captain John Rapids and about average at Pittsburg Landing and Lyons Ferry Hatchery. Mean fork lengths (95% confidence interval) of the PIT tagged groups ranged from 157.7 mm (157.3-158.1 mm) at Big Canyon to 172.9 mm (172.2-173.6 mm) at Captain John Rapids. Mean condition factors ranged from 1.06 at Captain John Rapids and Lyons Ferry Hatchery to 1.12 at Big Canyon. Estimated survival (95% confidence interval) of PIT tagged yearlings from release to Lower Granite Dam ranged from 87.0% (84.7-89.4%) for Pittsburg Landing to 95.2% (91.5-98.9%) for Captain John Rapids. Estimated survival from

X-chromosome inactivation and escape

PubMed Central

DISTECHE, CHRISTINE M.; BERLETCH, JOEL B.

2016-01-01

X-chromosome inactivation, which was discovered by Mary Lyon in 1961 results in random silencing of one X chromosome in female mammals. This review is dedicated to Mary Lyon, who passed away last year. She predicted many of the features of X inactivation, for e.g., the existence of an X inactivation center, the role of L1 elements in spreading of silencing and the existence of genes that escape X inactivation. Starting from her published work here we summarize advances in the field. PMID:26690513

L'opération de la Carte du Ciel dans les contextes institutionnel et technique de l'astronomie française à la fin du XIXe siècle

NASA Astrophysics Data System (ADS)

Le Guet Tully, F.; Sadsaoud, H.; de La Noë, J.

2008-06-01

Ce chapitre analyse le contexte institutionnel français dans lequel naît la Carte du Ciel. Dans les années 1880, le régime républicain réorganise totalement la recherche astronomique. À Paris, l'instrumentation est totalement renouvelée sous l'impulsion de Maurice Loewy. En province, les efforts de décentralisation permettent un accroissement significatif des arsenaux techniques de Marseille et Toulouse, ainsi que l'édification des établissements de Besançon, Lyon et Bordeaux. À Alger, la station astronomique créée sous le second Empire est transformée en un observatoire particulièrement dynamique grâce à l'implication de Charles Trépied. Ce panorama des établissements astronomiques permet de cerner les enjeux institutionnels et scientifiques qui concourent à l'engagement des observatoires de Paris, Bordeaux, Toulouse et Alger dans l'entreprise de la Carte du Ciel.

Rapport sur l'état du patrimoine astronomique dans les observatoires français de la fin du XIXè siècle

NASA Astrophysics Data System (ADS)

Damm, E.; Pécontal, E.

2012-12-01

Suite au colloque sur la sauvegarde du patrimoine astronomique organisé par le MAEE et la SAF, sous l'égide de l'UNESCO, qui a conduit à l'adoption de la Déclaration de Paris, les directeurs d'observatoires institutionnels qui étaient absents du colloque ont ressenti le besoin de discuter de ces conclusions prises en leur nom. L'initiative d'organiser une réunion des directeurs des Observatoires des Sciences de l'Univers (OSU) à ce sujet le 30 janvier 2012 a été prise par François Vernotte, directeur de l'Observatoire de Besançon. Le présent compte-rendu de visite résulte d'une initiative spontanée d'Emmanuel Pécontal, astronome responsable du Patrimoine à l'observatoire de Lyon, et d'Evelyne Damm, membre de la Commission Nationale de classement des Monuments Historiques (CNMH) et élue à la communauté d'agglomération des Portes de l'Essonne oû est sis l'observatoire de Camille Flammarion.

Lyon County Economic Development and Conservation Act

THOMAS, 113th Congress

Sen. Heller, Dean [R-NV

2013-01-28

Senate - 09/10/2013 Placed on Senate Legislative Calendar under General Orders. Calendar No. 172. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

Modern diagnosis of GERD: the Lyon Consensus.

PubMed

Gyawali, C Prakash; Kahrilas, Peter J; Savarino, Edoardo; Zerbib, Frank; Mion, Francois; Smout, André J P M; Vaezi, Michael; Sifrim, Daniel; Fox, Mark R; Vela, Marcelo F; Tutuian, Radu; Tack, Jan; Bredenoord, Albert J; Pandolfino, John; Roman, Sabine

2018-07-01

Clinical history, questionnaire data and response to antisecretory therapy are insufficient to make a conclusive diagnosis of GERD in isolation, but are of value in determining need for further investigation. Conclusive evidence for reflux on oesophageal testing include advanced grade erosive oesophagitis (LA grades C and D), long-segment Barrett's mucosa or peptic strictures on endoscopy or distal oesophageal acid exposure time (AET) >6% on ambulatory pH or pH-impedance monitoring. A normal endoscopy does not exclude GERD, but provides supportive evidence refuting GERD in conjunction with distal AET <4% and <40 reflux episodes on pH-impedance monitoring off proton pump inhibitors. Reflux-symptom association on ambulatory reflux monitoring provides supportive evidence for reflux triggered symptoms, and may predict a better treatment outcome when present. When endoscopy and pH or pH-impedance monitoring are inconclusive, adjunctive evidence from biopsy findings (histopathology scores, dilated intercellular spaces), motor evaluation (hypotensive lower oesophageal sphincter, hiatus hernia and oesophageal body hypomotility on high-resolution manometry) and novel impedance metrics (baseline impedance, postreflux swallow-induced peristaltic wave index) can add confidence for a GERD diagnosis; however, diagnosis cannot be based on these findings alone. An assessment of anatomy, motor function, reflux burden and symptomatic phenotype will therefore help direct management. Future GERD management strategies should focus on defining individual patient phenotypes based on the level of refluxate exposure, mechanism of reflux, efficacy of clearance, underlying anatomy of the oesophagogastric junction and psychometrics defining symptomatic presentations. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

[Interobserver agreement on electrocardiographic diagnosis of left ventricular hypertrophy in hypertensive patients in Andalusia. PREHVIA study].

PubMed

Martín-Rioboó, Enrique; López Granados, Amador; Cea Calvo, Luis; Pérula De Torres, Luis Angel; García Criado, Emilio; Anguita Sánchez, Manuel P; García Matarín, Lisardo; Molina Díaz, Rafael; Ureña Fernández, Tomas

2009-05-01

To assess the agreement between Primary Care (PC) doctors and a cardiology specialist in diagnosing left ventricular hypertrophy in the electrocardiograph (LVH-ECG) in hypertensive patients. Cross-sectional, multicentre study. Andalusian Primary Care Centres. A total of 120 PC doctors who using a random sample selected patients of 35 years or more with AHT of at least 6 months of progression. PRIMARY VARIABLES: Demographic data, risk factors and cardiovascular diseases were recorded. The LVH-ECG was evaluated by applying Cornell voltage criteria, Cornell and Sokolow-Lyon product. The PC researchers read the ECG first and the cardiologist made a second reading blind. A total of 570 patients (mean +/- SD of age, 65 +/- 11 years; 54.5% females); the LVH-ECG prevalence was 13.7% (95% CI, 10.8-16.6; 12.6% by Cornell and 1.6% by Sokolow-Lyon). The agreement in the diagnosis between the PC doctors and the cardiologist was 0.378 (95% CI, 0.272-0.486; disagreements in 15.5% of cases). The PC doctors slightly underestimated the LVH-ECG prevalence by Cornell and slightly overestimated it by the Sokolow-Lyon criteria. The agreement was also low for all of them (kappa = 0.367; 95% CI, 0.252-0.482, for Cornell, and kappa = 0.274; 95% CI: 0.093-0.454 for Sokolow-Lyon). The agreement between the diagnosis by the PC doctors and the cardiologist was low. The implications of this study suggest the need to improve the reading of ECG among PC doctors. The use of computerised systems could be a good option.

Pathologic Response, When Increased by Longer Interval, Is a Marker but Not the Cause of Good Prognosis in Rectal Cancer: 17-year Follow-up of the Lyon R90-01 Randomized Trial

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cotte, Eddy, E-mail: eddy.cotte@chu-lyon.fr; Lyon 1 University, EMR 3738, Lyon-Sud/Charles Mérieux Medical University, Oullins; Passot, Guillaume

Purpose: The Lyon R90-01 randomized trial investigated whether the interval between preoperative radiation therapy and surgery influenced rectal cancer outcome. Long-term results are reported here after a median follow-up of 17 years. Methods and Materials: Between February 1991 and December 1995, 210 patients from 29 French centers were randomly assigned (ratio of 1:1) to groups that waited either 2 weeks (short interval [SI]) or 6 to 8 weeks (long interval [LI]) between neoadjuvant radiation therapy and surgery. The primary endpoint was sphincter-preserving surgery. Results: LI group showed a better pathologic response (complete response or few residual cells) after radiation therapy than the SImore » group (26% vs 10.3%, P=.015). A better pathologic response was associated in multivariate analysis with significant improvement of overall survival (pT: P=.0293 and pN: P=.0048) but it was irrespective of the interval duration. The median follow-up was 17.2 years. The 5-, 10-, 15-, and 17-year overall survival rates were, respectively, 66.8%, 48.7%, 40.0%, and 34.0% for the SI group and, respectively, 67.1%, 53.5%, 41.9%, and 34.0% for the LI group. There were no significant differences between groups in terms of survival (P=.7656) or local recurrence rates (SI: 14.4% vs LI: 12.1%, respectively; P=.6202). Of 24 local disease recurrences, 20 (83%) occurred during the first 2 postoperative years, and all but one (96%) occurred during the first 5 postoperative years. The rate of second new malignancies was 9.4% (19 patients). Conclusions: The radiation-induced sterilization rate of the preoperative cancer specimen was a marker of good prognosis. The interval duration (the treatment being the same) although it is modifying the sterilization rate has no impact on survival. Radiation therapy did not postpone local recurrence, because the rate of local relapse after 5 years was low. Radiation-induced cancers after radiation therapy were unusual and should not

Practical Session: Logistic Regression

NASA Astrophysics Data System (ADS)

Clausel, M.; Grégoire, G.

2014-12-01

An exercise is proposed to illustrate the logistic regression. One investigates the different risk factors in the apparition of coronary heart disease. It has been proposed in Chapter 5 of the book of D.G. Kleinbaum and M. Klein, "Logistic Regression", Statistics for Biology and Health, Springer Science Business Media, LLC (2010) and also by D. Chessel and A.B. Dufour in Lyon 1 (see Sect. 6 of http://pbil.univ-lyon1.fr/R/pdf/tdr341.pdf). This example is based on data given in the file evans.txt coming from http://www.sph.emory.edu/dkleinb/logreg3.htm#data.

Regression of electrocardiographic left ventricular hypertrophy or strain is associated with lower incidence of cardiovascular morbidity and mortality in hypertensive patients independent of blood pressure reduction - A LIFE review.

PubMed

Bang, Casper N; Devereux, Richard B; Okin, Peter M

2014-01-01

Cornell product criteria, Sokolow-Lyon voltage criteria and electrocardiographic (ECG) strain (secondary ST-T abnormalities) are markers for left ventricular hypertrophy (LVH) and adverse prognosis in population studies. However, the relationship of regression of ECG LVH and strain during antihypertensive therapy to cardiovascular (CV) risk was unclear before the Losartan Intervention for Endpoint Reduction in Hypertension (LIFE) study. We reviewed findings on ECG LVH regression and strain over time in 9193 hypertensive patients with ECG LVH at baseline enrolled in the LIFE study. The composite endpoint of CV death, nonfatal MI, or stroke occurred in 1096 patients during 4.8±0.9years follow-up. In Cox multivariable models adjusting for randomized treatment, known risk factors including in-treatment blood pressure, and for severity ECG LVH by Cornell product and Sokolow-Lyon voltage, baseline ECG strain was associated with a 33% higher risk of the LIFE composite endpoint (HR. 1.33, 95% CI [1.11-1.59]). Development of new ECG strain between baseline and year-1 was associated with a 2-fold increased risk of the composite endpoint (HR. 2.05, 95% CI [1.51-2.78]), whereas the risk associated with regression or persistence of ECG strain was attenuated and no longer statistically significant (both p>0.05). After controlling for treatment with losartan or atenolol, for baseline Framingham risk score, Cornell product, and Sokolow-Lyon voltage, and for baseline and in-treatment systolic and diastolic blood pressure, 1 standard deviation (SD) lower in-treatment Cornell product was associated with a 14.5% decrease in the composite endpoint (HR. 0.86, 95% CI [0.82-0.90]). In a parallel analysis, 1 SD lower in-treatment Sokolow-Lyon voltage was associated with a 16.6% decrease in the composite endpoint (HR. 0.83, 95% CI [0.78-0.88]). The LIFE study shows that evaluation of both baseline and in-study ECG LVH defined by Cornell product criteria, Sokolow-Lyon voltage criteria or

Relationships between acid deposition, watershed characteristics, and stream chemistry in Maryland's coastal plain. Final report. Volume 1. Text. Report for May 1984-June 1985

DOE Office of Scientific and Technical Information (OSTI.GOV)

Campbell, S.; Bartoshesky, J.; Heimbuch, D.

1987-06-01

Precipitation and stream-water chemistry data were collected from three watersheds in the Coastal Plain region of Maryland during the period May 1984 through June 1985 in an attempt to determine the potential effects of acidic deposition on the chemistry of these streams. The study streams included Lyons Creek, Morgan Creek, and Granny Finley Branch; these streams were chosen based on their differential responses to storm events observed in a survey of Coastal Plain streams in the spring of 1983. Lyons Creek typically exhibited lower pH, acid-neutralizing capacity, and concentrations of base cations than observed in the other streams. Sulfate massmore » balances suggest that the soils in the Lyons Creek watershed also have less affinity for sulfur retention than do soils of the other watersheds. Acidic pulses were observed in all three streams during the spring months; however, the magnitude of these pulses was less than that observed in 1983. Modeling of the relationships between precipitation chemistry, watershed interactions, and stream chemistry suggests that precipitation acidity can influence stream-water acidity, depending upon hydrological conditions and availabiility of acid-neutralizing materials in the watersheds.« less

Practical Session: Multiple Linear Regression

NASA Astrophysics Data System (ADS)

Clausel, M.; Grégoire, G.

2014-12-01

Three exercises are proposed to illustrate the simple linear regression. In the first one investigates the influence of several factors on atmospheric pollution. It has been proposed by D. Chessel and A.B. Dufour in Lyon 1 (see Sect. 6 of http://pbil.univ-lyon1.fr/R/pdf/tdr33.pdf) and is based on data coming from 20 cities of U.S. Exercise 2 is an introduction to model selection whereas Exercise 3 provides a first example of analysis of variance. Exercises 2 and 3 have been proposed by A. Dalalyan at ENPC (see Exercises 2 and 3 of http://certis.enpc.fr/~dalalyan/Download/TP_ENPC_5.pdf).

Biologically inspired emotion recognition from speech

NASA Astrophysics Data System (ADS)

Caponetti, Laura; Buscicchio, Cosimo Alessandro; Castellano, Giovanna

2011-12-01

Emotion recognition has become a fundamental task in human-computer interaction systems. In this article, we propose an emotion recognition approach based on biologically inspired methods. Specifically, emotion classification is performed using a long short-term memory (LSTM) recurrent neural network which is able to recognize long-range dependencies between successive temporal patterns. We propose to represent data using features derived from two different models: mel-frequency cepstral coefficients (MFCC) and the Lyon cochlear model. In the experimental phase, results obtained from the LSTM network and the two different feature sets are compared, showing that features derived from the Lyon cochlear model give better recognition results in comparison with those obtained with the traditional MFCC representation.

77 FR 56179 - Lyon & Mineral Resource Advisory Committee

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-12

.... The purpose of the committee is to improve collaborative relationships and to provide advice and... II projects. (2) Public Comment. Persons who wish to bring related matters to the attention of the...

76 FR 47637 - Kansas Disaster #KS-00055

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-05

... disaster declaration on 07/29/2011, Private Non- Profit organizations that provide essential services of... Counties: Barton, Clay, Cloud, Hamilton, Jewell, Lincoln, Logan, Lyon, Marion, Mitchell, Morton, Osage...

E-cigarettes and E-hookahs

MedlinePlus

Electronic cigarettes; Electronic hookahs; Vaping; Electronic nicotine delivery systems; Smoking - electronic cigarettes ... Elsevier Saunders; 2016:chap 46. Callahan-Lyon P. Electronic cigarettes: human health effects. Tob Control . 2014;23( ...

The effect of restored and native oxbows on hydraulic loads of nutrients and stream water quality

USGS Publications Warehouse

Kalkhoff, Stephen J.; Hubbard, Laura E.; Joseph P.Schubauer-Berigan,

2016-01-01

The use of oxbow wetlands has been identified as a potential strategy to reduce nutrient transport from agricultural drainage tiles to streams in Iowa. In 2013 and 2014, a study was conducted in north-central Iowa in a native oxbow in the Lyons Creek watershed and two restored oxbow wetlands in the Prairie Creek watershed (Smeltzer west and Smeltzer east) to assess their effectiveness at reducing nitrogen and phosphorus loads. The tile line inlets carrying agricultural runoff to the oxbows, the outfall from the oxbows, and the surface waters in the streams receiving the outfall water were monitored for discharge and nutrients from February 2013 to September 2015. Smeltzer west and east also had four monitoring wells each, two in the upland and two between the oxbow and Prairie Creek to monitor surface water-groundwater interaction. The Smeltzer west and east oxbow sites also were instrumented to continuously measure the nitrate concentration. Rainfall was measured at one Lyons Creek and one Smeltzer site. Daily mean nitrate-N concentrations in Lyons Creek in 2013 ranged from 11.8 mg/L to 40.9 mg/L, the median daily mean nitrate-N concentration was 33.0 mg/L. Daily mean nitrate-N concentrations in Prairie Creek in 2013 ranged from 0.07 mg/L in August to 32.2 mg/L in June. In 2014, daily mean nitrate-N concentrations in Prairie Creek ranged from 0.17 mg/L in April to 26.7 mg/L in July; the daily mean nitrate-N concentration for the sampled period was 9.78 mg/L. Nutrient load reduction occurred in oxbow wetlands in Lyons and Prairie Creek watersheds in north-central Iowa but efficiency of reduction was variable. Little nutrient reduction occurred in the native Lyons Creek oxbow during 2013. Concentrations of all nutrient constituents were not significantly (P>0.05, Wilcoxon rank sum) different in water discharging from the tile line than in water leaving the Lyons Creek oxbow. A combination of physical features and flow conditions suggest that the residence time of

Evaluation of the malaria rapid diagnostic test VIKIA malaria Ag Pf/Pan™ in endemic and non-endemic settings

PubMed Central

2013-01-01

Background Malaria rapid diagnostic tests (RDTs) are a useful tool in endemic malaria countries, where light microscopy is not feasible. In non-endemic countries they can be used as complementary tests to provide timely results in case of microscopy inexperience. This study aims to compare the new VIKIA Malaria Ag Pf/Pan™ RDT with PCR-corrected microscopy results and the commonly used CareStart™ RDT to diagnose falciparum and non-falciparum malaria in the endemic setting of Bamako, Mali and the non-endemic setting of Lyon, France. Methods Blood samples were collected during a 12-months and six-months period in 2011 from patients suspected to have malaria in Lyon and Bamako respectively. The samples were examined by light microscopy, the VIKIA Malaria Ag Pf/Pan™ test and in Bamako additionally with the CareStart™ RDT. Discordant results were corrected by real-time PCR. Sensitivity, specificity, positive predictive value and negative predictive value were used to evaluate test performance. Results Samples of 877 patients from both sites were included. The VIKIA Malaria Ag Pf/Pan™ had a sensitivity of 98% and 96% for Plasmodium falciparum in Lyon and Bamako, respectively, performing similar to PCR-corrected microscopy. Conclusions The VIKIA Malaria Ag Pf/Pan™ performs similar to PCR-corrected microscopy for the detection of P. falciparum, making it a valuable tool in malaria endemic and non-endemic regions. PMID:23742633

Evaluation of the malaria rapid diagnostic test VIKIA malaria Ag Pf/Pan™ in endemic and non-endemic settings.

PubMed

Eibach, Daniel; Traore, Boubacar; Bouchrik, Mourad; Coulibaly, Boubacar; Coulibaly, Nianégué; Siby, Fanta; Bonnot, Guillaume; Bienvenu, Anne-Lise; Picot, Stéphane

2013-06-06

Malaria rapid diagnostic tests (RDTs) are a useful tool in endemic malaria countries, where light microscopy is not feasible. In non-endemic countries they can be used as complementary tests to provide timely results in case of microscopy inexperience. This study aims to compare the new VIKIA Malaria Ag Pf/Pan™ RDT with PCR-corrected microscopy results and the commonly used CareStart™ RDT to diagnose falciparum and non-falciparum malaria in the endemic setting of Bamako, Mali and the non-endemic setting of Lyon, France. Blood samples were collected during a 12-months and six-months period in 2011 from patients suspected to have malaria in Lyon and Bamako respectively. The samples were examined by light microscopy, the VIKIA Malaria Ag Pf/Pan™ test and in Bamako additionally with the CareStart™ RDT. Discordant results were corrected by real-time PCR. Sensitivity, specificity, positive predictive value and negative predictive value were used to evaluate test performance. Samples of 877 patients from both sites were included. The VIKIA Malaria Ag Pf/Pan™ had a sensitivity of 98% and 96% for Plasmodium falciparum in Lyon and Bamako, respectively, performing similar to PCR-corrected microscopy. The VIKIA Malaria Ag Pf/Pan™ performs similar to PCR-corrected microscopy for the detection of P. falciparum, making it a valuable tool in malaria endemic and non-endemic regions.

18. Topside facility, interior of facility manager's room, view towards ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

18. Topside facility, interior of facility manager's room, view towards west. Lyon - Whiteman Air Force Base, Oscar O-1 Minuteman Missile Alert Facility, Southeast corner of Twelfth & Vendenberg Avenues, Knob Noster, Johnson County, MO

Find a Doctor

MedlinePlus

... Cassini Catalano Caviness Cazden Chait Cham Chambi Chan Chang Charles Charness Charous Charpied Cheng Chhetri Childers Chitkara ... Lynch Lyons Machado Maciunas Mahant Mahon Majewski Malhado-Chang Mangels Mann Manning Sifers Maragos Marantz Marcus Marden ...

10. 351st Missile Wing Maintenance insignia on wall opposite the ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

10. 351st Missile Wing Maintenance insignia on wall opposite the entrance. Lyon - Whiteman Air Force Base, Minuteman Missile Launch Facility Trainer T-12, Northeast of Oscar-01 Missile Alert Facility, Knob Noster, Johnson County, MO

76 FR 19030 - Lyon & Mineral County Resource Advisory Committee

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-06

... Committee will meet in Smith Valley, Nevada. The committee is meeting as authorized under the Secure Rural...: The meeting will be held April 25, 2011 at 9 a.m. ADDRESSES: The meeting will be held at the Smith Valley Library at 32 Day Lane, Smith Valley, NV 89444. Written comments should be sent to Mike Crawley...

26 CFR 1.42-4 - Application of not-for-profit rules of section 183 to low-income housing credit activities.

Code of Federal Regulations, 2010 CFR

2010-04-01

... is allowable may be limited or disallowed under other provisions of the Code or principles of tax law.... 34 (“sham” or “economic substance” analysis); and Frank Lyon Co. v. Commissioner, 435 U.S. 561 (1978...

77 FR 27417 - Foreign-Trade Zone 220-Sioux Falls, SD; Notification of Proposed Production Activity, Rosenbauer...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-10

... is used for the production of emergency vehicles and firefighting equipment (pumps, tankers, rescue... drives, DC motors, static converters, rechargeable flashlights, flashlight parts, electrical foam..., LLC, (Emergency Vehicles/Firefighting Equipment), Lyons, SD The Sioux Falls Development Foundation...

Genetics Home Reference: atopic dermatitis

MedlinePlus

... JK, Weinreich MA, Hauk PJ, Reynolds PR, Lyons JJ, Nelson CG, Ruffo E, Dorjbal B, Glauzy S, Yamakawa ... J, Niemela J, Zhang Y, Rosenzweig SD, McElwee JJ, DiMaggio T, Matthews HF, Jones N, Stone KD, ...

Eyes - bulging

MedlinePlus

McNab AA. Proptosis at different ages. In: Lambert SR, Lyons CJ, eds. Taylor and Hoyt's Pediatric Ophthalmology and Strabismus . ... of the neonatal eye. In: Martin RJ, Fanaroff AA, Walsh MC, eds. Fanaroff and Martin's Neonatal-Perinatal ...

Medical climatology in France: the persistence of Neo-Hippocratic ideas in the first half of the twentieth century.

PubMed

Osborne, Michael A; Fogarty, Richard S

2012-01-01

In interwar France the Lyonnais physician Marius Piéry undertook an ambitious Neo-Hippocratic research program to study how atmospheric and terrestrial environments influenced health. Lyon had a number of institutions linked to the colonies and was a center for the training of military physicians. Colonial physicians had a long tradition of contending with the diseases of tropical environments, and their ideas and many returned colonials circulated in Lyon and its region. Piéry was a physician during World War I and published on military medical topics. He also included colonial and military health concerns in his more mature works from the 1930s. An advocate of the close study of the physical sciences, he investigated the radioactive gases of health spas and the effects of altitude on pulmonary tuberculosis, and he directed a meteorological observatory.

Compressible convection in geophysical fluids: comparison of anelastic, anelastic liquid and full numerical simulations

NASA Astrophysics Data System (ADS)

Curbelo, Jezabel; Alboussiere, Thierry; Labrosse, Stephane; Dubuffet, Fabien; Ricard, Yanick

2015-11-01

In this talk we describe the numerical method implemented to study convection in a fully compressible two-dimensional model, which may be reduced to the different simplifications such as the anelastic approximation and the anelastic liquid approximation. Various equations of state are considered, from the ideal gas equation to equations related to liquid or solid condensed matter. We are particularly interested in the total value and spatial distribution of viscous dissipation. We analyze the solutions obtained with each approximation in a wide range of dimensionless parameters and compare the domain of validity of each of them. The authors are grateful to the LABEX Lyon Institute of Origins (ANR-10-LABX-0066) of the Universite de Lyon for its financial support ``Investissements d'Avenir'' (ANR-11-IDEX-0007) of the French government operated by the National Research Agency (ANR).

RecPhyloXML - a format for reconciled gene trees.

PubMed

Duchemin, Wandrille; Gence, Guillaume; Arigon Chifolleau, Anne-Muriel; Arvestad, Lars; Bansal, Mukul S; Berry, Vincent; Boussau, Bastien; Chevenet, François; Comte, Nicolas; Davín, Adrián A; Dessimoz, Christophe; Dylus, David; Hasic, Damir; Mallo, Diego; Planel, Rémi; Posada, David; Scornavacca, Celine; Szöllosi, Gergely; Zhang, Louxin; Tannier, Éric; Daubin, Vincent

2018-05-14

A reconciliation is an annotation of the nodes of a gene tree with evolutionary events-for example, speciation, gene duplication, transfer, loss, etc-along with a mapping onto a species tree. Many algorithms and software produce or use reconciliations but often using different reconciliation formats, regarding the type of events considered or whether the species tree is dated or not. This complicates the comparison and communication between different programs. Here, we gather a consortium of software developers in gene tree species tree reconciliation to propose and endorse a format that aims to promote an integrative-albeit flexible-specification of phylogenetic reconciliations. This format, named recPhyloXML, is accompanied by several tools such as a reconciled tree visualizer and conversion utilities. http://phylariane.univ-lyon1.fr/recphyloxml/. wandrille.duchemin@univ-lyon1.fr. There is no supplementary data associated with this publication.

Supporting Our Nation's Nuclear Industry

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lyons, Peter

2011-12-16

On the 60th anniversary of the world's first nuclear power plant to produce electricity, Assistant Secretary for Nuclear Energy Peter Lyons discusses the Energy Department's and the Administration's commitment to promoting a nuclear renaissance in the United States.

The 1995 attempted derailing of the French TGV (high-speed train) and a quantitative analysis of 181 rail sabotage attempts.

DOT National Transportation Integrated Search

2010-03-01

On August 26, 1995, the Saturday of the final and busiest weekend of Frances summer holiday season, terrorists attempted to derail the TGV (Train Grande Vitesse) between Lyon and Paris by planting a bomb. Fortunately, their crude triggering mec...

2. T12, exterior overall view, view from just outside the ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

2. T-12, exterior overall view, view from just outside the security fence looking southeast. Lyon - Whiteman Air Force Base, Minuteman Missile Launch Facility Trainer T-12, Northeast of Oscar-01 Missile Alert Facility, Knob Noster, Johnson County, MO

Evaluating Comparability in the Scoring of Performance Assessments for Accountability Purposes

ERIC Educational Resources Information Center

Lyons, Susan; Evans, Carla

2017-01-01

This brief summarizes "Comparability in Balanced Assessment Systems for State Accountability," published in "Educational Measurement: Issues and Practice" (Evans & Lyons 2017). The study evaluated comparability claims in local scoring of performance assessments across districts participating in New Hampshire's Performance…

Supporting Our Nation's Nuclear Industry

ScienceCinema

Lyons, Peter

2018-02-07

On the 60th anniversary of the world's first nuclear power plant to produce electricity, Assistant Secretary for Nuclear Energy Peter Lyons discusses the Energy Department's and the Administration's commitment to promoting a nuclear renaissance in the United States.

A rainfall risk analysis thanks to an GIS based estimation of urban vulnerability

NASA Astrophysics Data System (ADS)

Renard, Florent; Pierre-Marie, Chapon

2010-05-01

The urban community of Lyon, situated in France in the north of the Rhône valley, comprises 1.2 million inhabitants within 515 km ². With such a concentration of issues, policy makers and local elected officials therefore attach great importance to the management of hydrological risks, particularly due to the inherent characteristics of the territory. If the hazards associated with these risks in the territory of Lyon have been the subject of numerous analyses, studies on the vulnerability of greater Lyon are rare and have common shortcomings that impair their validity. We recall that the risk is seen as the classic relationship between the probability of occurrence of hazards and vulnerability. In this article, this vulnerability will be composed of two parts. The first one is the sensitivity of the stakes facing hydrological hazards as urban runoff, that is to say, their propensity to suffer damage during a flood (Gleize and Reghezza, 2007). The second factor is their relative importance in the functioning of the community. Indeed, not all the stakes could provide the same role and contribution to the Greater Lyon. For example, damage to the urban furniture such as bus shelter seems less harmful to the activities of the urban area than that of transport infrastructure (Renard and Chapon, 2010). This communication proposes to assess the vulnerability of Lyon urban area facing to hydrological hazards. This territory is composed of human, environmental and material stakes. The first part of this work is to identify all these issues so as to completeness. Then, is it required to build a "vulnerability index" (Tixier et al, 2006). Thus, it is necessary to use methods of multicriteria decision aid to evaluate the two components of vulnerability: the sensitivity and the contribution to the functioning of the community. Finally, the results of the overall vulnerability are presented, and then coupled to various hazards related to water such as runoff associated with

Hyperactivity and sugar

MedlinePlus

... Elsevier; 2016:chap 2. Lyon M, Murray MT. Attention deficit hyperactivity disorder. In: Pizzorno JE, Murray MT, eds. Textbook of ... Livingstone; 2013:chap 150. Sawni A, Kemper KJ. Attention deficit hyperactivity disorder. In: Rakel D, ed. Integrative Medicine . 4th ed. ...

20. Readiness Crew Building interior, upper level corridor. This corridor ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

20. Readiness Crew Building interior, upper level corridor. This corridor runs from northwest to southeast. Photograph taken at the northwest end looking southeast. Lyon - Whiteman Air Force Base, Bomber Alert Facility S-6, 1300 Alert Road, Knob Noster, Johnson County, MO

Project no. B371 : acoustic emission and strain gage monitoring of WIDOT structure B-5-158, Tower Drive Tied Arch, Green Bay, Wisconsin

DOT National Transportation Integrated Search

1993-06-16

The City of South Lyon converted the traffic signals on the street network from fixed time control to the Sydney Coordinated Adaptive Traffic System (SCATS). The objectives of this research study were to analyze the differences in certain delay param...

Central Missouri AGRIService, LLC - Clean Water Act Public Notice

EPA Pesticide Factsheets

The EPA is providing notice of a proposed Administrative Penalty Assessment against Central Missouri AGRIService, LLC, a business located at 211 North Lyon Avenue in Marshall, MO, for alleged CWA violations at a construction site located at 1324 Santa Fe T

Monitoring and Evaluation of Yearling Fall Chinook Salmon (Oncorhynchus tshawytscha) Released from Acclimation Facilities Upstream of Lower Granite Dam; 1999 Annual Report.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rocklage, Stephen J.; Kellar, Dale S.

2005-07-01

The Nez Perce Tribe, in cooperation with the U.S. Fish and Wildlife Service and Washington Department of Fish and Wildlife, conducted monitoring and evaluation studies on Lyons Ferry Hatchery reared yearling fall Chinook salmon Oncorhynchus tshawytscha that were acclimated and released at three Fall Chinook Acclimation Project (FCAP) sites upstream of Lower Granite Dam along with yearlings released on-station from Lyons Ferry Hatchery in 1999. This was the fourth year of a long-term project to supplement natural spawning populations of Snake River stock fall Chinook salmon upstream of Lower Granite Dam. The 453,117 yearlings released from the Fall Chinook Acclimationmore » Project facilities not only slightly exceeded the 450,000 fish quota, but a second release of 76,386 yearlings (hereafter called Surplus) were acclimated at the Big Canyon facility and released about two weeks after the primary releases. We use Passive Integrated Transponder (PIT) tag technology to monitor the primary performance measures of survival to mainstem dams and migration timing. We also monitor size, condition and tag/mark retention at release. We released 9,941 PIT tagged yearlings from Pittsburg Landing, 9,583 from Big Canyon, 2,511 Big Canyon Surplus and 2,494 from Captain John Rapids. The Washington Department of Fish and Wildlife released 983 PIT tagged yearlings from Lyons Ferry Hatchery. Fish health sampling indicated that, overall, bacterial kidney disease levels could be considered relatively low and did not appear to increase after transport to the acclimation facilities. Compared to prior years, Quantitative Health Assessment Indices were relatively low at Pittsburg Landing and Lyons Ferry Hatchery and relatively high at Big Canyon and Captain John Rapids. Mean fork lengths (95% confidence interval) of the release groups ranged from 147.4 mm (146.7-148.1 mm) at Captain John Rapids to 163.7 mm (163.3-164.1 mm) at Pittsburg Landing. Mean condition factors ranged from 1.04 at

CARCINOGENICITY OF HOUSEHOLD SOLID FUEL COMBUSTION AND OF HIGH-TEMPERATURE FRYING

EPA Science Inventory

In October, 2006, 19 scientists from eight countries met at the International Agency for Research on Cancer (IARC) in Lyon, France, to assess the carcinogenicity of household solid fuel combustion (coal and biomass) and of high-temperature frying. These assessments will be publi...

76 FR 61151 - Enhanced-Use Lease (EUL) of Department of Veterans Affairs (VA) Real Property for the Development...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-03

...) Real Property for the Development of a Permanent Supportive Housing Facility in Lyons, NJ AGENCY..., develop, construct, manage, maintain and operate the EUL development. As consideration for the lease, the...-term self-sufficiency. FOR FURTHER INFORMATION CONTACT: Edward Bradley, Office of Asset Enterprise...

78 FR 32381 - Applications for New Awards, Investing in Innovation Fund, Scale-up and Validation Grants...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-30

... DEPARTMENT OF EDUCATION Applications for New Awards, Investing in Innovation Fund, Scale- up and Validation Grants; Correction AGENCY: Office of Innovation and Improvement, Department of Education. ACTION.... FOR FURTHER INFORMATION CONTACT: Carol Lyons, U.S. Department of Education, 400 Maryland Avenue SW...

English Teaching at Lilydale High.

ERIC Educational Resources Information Center

Mayer, Valerie; Matcott, Mark; Lyons, Janet; Flessa, Demi; Hayman, Anna; Hough, Peter

2002-01-01

Presents six narratives from teachers including: "VCE English at Lilydale High School" (Valerie Mayer); "Should 'I' Be Their Teacher" (Mark Matcott); "Teaching Poetry to Year 7 English Students" (Janet Lyons); "Creative Art Therapy and Mandalas" (Demi Flessa); "Would the 'Real' Teacher Please Stand…

Indium-oxide nanoparticles for RRAM devices compatible with CMOS back-end-off-line

NASA Astrophysics Data System (ADS)

León Pérez, Edgar A. A.; Guenery, Pierre-Vincent; Abouzaid, Oumaïma; Ayadi, Khaled; Brottet, Solène; Moeyaert, Jérémy; Labau, Sébastien; Baron, Thierry; Blanchard, Nicholas; Baboux, Nicolas; Militaru, Liviu; Souifi, Abdelkader

2018-05-01

We report on the fabrication and characterization of Resistive Random Access Memory (RRAM) devices based on nanoparticles in MIM structures. Our approach is based on the use of indium oxide (In2O3) nanoparticles embedded in a dielectric matrix using CMOS-full-compatible fabrication processes in view of back-end-off-line integration for non-volatile memory (NVM) applications. A bipolar switching behavior has been observed using current-voltage measurements (I-V) for all devices. Very high ION/IOFF ratios have been obtained up to 108. Our results provide insights for further integration of In2O3 nanoparticles-based devices for NVM applications. He is currently a Postdoctoral Researcher in the Institute of Nanotechnologies of Lyon (INL), INSA de Lyon, France, in the Electronics Department. His current research include indium oxide nanoparticles for non-volatile memory applications, and the integrations of these devices in CMOS BEOL.

The Effect of Restored and Native Oxbows on Hydraulic Loads ...

EPA Pesticide Factsheets

The use of oxbow wetlands has been identified as a potential strategy to reduce nutrient transport from agricultural drainage tiles to streams in Iowa. In 2013 and 2014, a study was conducted in north central Iowa in a native oxbow in the Lyons Creek watershed and two reconstructed oxbows in the Prairie Creek watershed (Smeltzer west and Smeltzer east) to assess their effectiveness at reducing nitrogen and phosphorus loads. The tile line inlets carrying agricultural runoff to the oxbows, the outfall from the oxbows and the surface waters in the streams receiving the outfall water were monitored for discharge and nutrients from February 2013 to September 2015. Smeltzer west and east also had four monitoring wells each, two in the upland and two between the oxbow and Prairie Creek to monitor surface water groundwater interaction. The Smeltzer west and east oxbow sites also were instrumented to continuously measure the nitrate concentration. Rainfall was measured at one Lyons Creek and one Smeltzer site. Daily mean nitrate-N concentrations in Lyons Creek in 2013 ranged from 41 mg/L to 11.8 mg/L, the median daily mean nitrate-N concentration was 33 mg/L. Daily mean nitrate-N concentrations in Prairie Creek in 2013 ranged from 15.0 mg/L to 32 mg/L in June. The median daily mean nitrate-N concentration for the sampled period was 11.2 mg/L. In 2014, daily mean nitrate-N concentrations in Prairie Creek ranged from 0.17 mg/L to 26.7 mg/L in July; the daily mean

Florida Educational Facilities, 2000.

ERIC Educational Resources Information Center

Florida State Dept. of Education, Tallahassee. Office of Educational Facilities.

This publication describes Florida school and community college facilities completed in 2000, including photographs and floor plans. The facilities profiled are:J. R. Arnold High School (Bay County); Falcon Cove Middle School (Broward); Floranada Elementary School (Broward); Lyons Creek Middle School (Broward); Parkside Elementary School…

Places of Belonging: Awakening a Zone of Complacency

ERIC Educational Resources Information Center

Foley, Jean Ann

2013-01-01

Although education has seen trends of progressive ideologies that promote student and teacher empowerment (Ayers, 2011; Lyons, Catallozzi, & Benson, 1998; Spring, 2008), the dominant educational discourse mirrors a business model of efficiency expressed by the social economist Lester Frank Ward (1872). Evidence of contemporary education…

An Integrative Approach to Understanding and Predicting the Consequences of Fatigue on Cognitive Performance

DTIC Science & Technology

2009-12-01

e.g., Drummond, Brown, Salamat, & Gillin, 2004; Saper, Scammell , & Lu, 2005; Thomas et al., 2000). Some of the insights from neurophysiological...C.B., Scammell , T.E., & Lu, J. (2005). Hypothalamic regulation of sleep and circadian rhythms. Nature. 437(7063), 1257-1263. Schreiber, B. T., Lyon

76 FR 53927 - Kansas; Major Disaster and Related Determinations

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-30

... determinations. DATES: Effective Date: July 29, 2011. FOR FURTHER INFORMATION CONTACT: Peggy Miller, Office of... Public Assistance and Hazard Mitigation will be limited to 75 percent of the total eligible costs...: Barton, Clay, Cloud, Hamilton, Jewell, Lincoln, Logan, Lyon, Marion, Mitchell, Morton, Osage, Osborne...

The Handbook of Student Affairs Administration. The Jossey-Bass Higher and Adult Education Series.

ERIC Educational Resources Information Center

Barr, Margaret J.; And Others

This handbook on student affairs administration contains the following papers: (1) "The Importance of Institutional Mission" (Lyons); (2) "Institutional Governance and the Role of Student Affairs" (Pembroke); (3) "Assessing Campus Environments" (Kuh); (4) "Fiscal Pressures on Higher Education and Student Affairs" (Schuh); (5) "Identifying and…

Integrated systems of weed management in organic transplated vidalia sweet onion production

USDA-ARS?s Scientific Manuscript database

Field experiments were conducted from 2008 through 2010 near Lyons, GA to develop integrated weed management systems for organic Vidalia® sweet onion production. Treatments were a factorial arrangement of summer solarization, cultivation with a tine weeder, and a clove oil herbicide. Plots were so...

75 FR 7342 - Airworthiness Directives; SICLI Halon 1211 Portable Fire Extinguishers as Installed on Various...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-02-19

... INFORMATION CONTACT: For transport airplanes: Dan Rodina, Aerospace Engineer, International Branch, ANM-116...) 227-2125; fax (425) 227-1149. For small airplanes: Leslie B. Taylor, Aerospace Engineer, Standards... concern. The results of the ongoing investigation have now established that LyonTech Engineering Ltd, a UK...

Better Understanding Learning Disabilities: New Views from Research and Their Implications for Education and Public Policies.

ERIC Educational Resources Information Center

Lyon, G. Reid, Ed.; And Others

This book examines critical issues in classification and definition of learning disabilities; the development of theory in learning disabilities; the development of cognitive, developmental, and educational models of learning disabilities; and social and public policy in learning disabilities. After an introductory chapter by G. Reid Lyon and…

78 FR 31974 - Notice of Availability of the Draft Environmental Impact Statement and Notice of Public Meetings...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-28

... counties of Washoe, Storey, Lyon, and Churchill. DATES: Submit written comments on the RMP/DEIS on or... the public meetings. The public meetings will be held at the following locations: Fallon at Churchill... County Library, and the Churchill County Library Natural Resources Library, Department of the Interior...

Using the Classroom to Cultivate Student Support for Participation in Campus Life: The Call for Civic Education Interventions

ERIC Educational Resources Information Center

Strachan, J. Cherie

2008-01-01

Extracurricular campus activities mirror the effects of associational life on political participation (Kuh 1995; Pascarella, Ethington, and Smart 1988; Verba, Schlozman, and Brady 1995). As encouraging student participation in such activities can be difficult (Kuh, Schuh, Whitt, Andreas, Lyons, Strange, Krehbiel, and MacKay 1991), this project…

Genetics Home Reference: head and neck squamous cell carcinoma

MedlinePlus

... Lyons B, Fox SB, Rischin D, Dobrovic A, Solomon B. Differential mechanisms of CDKN2A (p16) alteration in oral tongue squamous cell carcinomas and correlation with patient outcome. Int J Cancer. 2014 Aug 15;135(4):887-95. doi: 10.1002/ijc.28727. Epub ...

Restoring Law and Order: The Kentucky State Guard in the Black Patch War of 1907-1909

DTIC Science & Technology

2011-05-19

Fulton, Galloway , Graves, Hickman, Hopkins, Livingston, Logan, Lyon, Marshall, McCracken, Simpson, Todd, and Trigg. The region’s name refers to the...Infernal Machine Addressed to Sanford Hall Found in Paducah Post Office,” September 28, 1908, Will Scott , “Herbert Hall Murdered: His Fate Told By

77 FR 46091 - Notice of Proposed Administrative Settlement Pursuant to the Comprehensive Environmental Response...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-08-02

... Copper Mine Site AGENCY: Environmental Protection Agency. ACTION: Notice, request for public comments... concerning the ANACONDA COPPER MINE SITE (the ``Site''), located in Yerington, Lyon County, Nevada. The... Peak Services Agreement for the Anaconda Copper Mine Site, and Region IX Docket No. 9-2012-07. FOR...

4. View of the launch closure. Transporter/erector mounts at center, ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

4. View of the launch closure. Transporter/erector mounts at center, security antenna at left, access building at right. View towards south. Lyon - Whiteman Air Force Base, Minuteman Missile Launch Facility Trainer T-12, Northeast of Oscar-01 Missile Alert Facility, Knob Noster, Johnson County, MO

Response of the Imported Willow Leaf Beetle to Bacillus thuringiensis var. san diego on Poplar Willow1

Treesearch

Leah S. Bauer

1992-01-01

The imported willow leaf beetle, Plagiodera versicolora (Laicharting) (Coleoptera: Chrysomelidae), a multivoltine defoliator of willow and poplar (Salicaceae), is considered a significant pest throughout eastern North America (W.T. Johnson and H.H Lyon, "Insects that Feed on Trees and Shrubs," Cornell University Press, Ithaca, 1988)....

40 CFR Appendix III to Part 1068 - High-Altitude Counties

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 33 2014-07-01 2014-07-01 false High-Altitude Counties III Appendix III to Part 1068 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR POLLUTION... Lander Lincoln Lyon Mineral Nye Pershing Storey Washoe White Pine State of New Mexico Bernalillo Catron...

40 CFR Appendix III to Part 1068 - High-Altitude Counties

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 34 2013-07-01 2013-07-01 false High-Altitude Counties III Appendix III to Part 1068 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR POLLUTION... Lander Lincoln Lyon Mineral Nye Pershing Storey Washoe White Pine State of New Mexico Bernalillo Catron...

40 CFR Appendix III to Part 1068 - High-Altitude Counties

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 34 2012-07-01 2012-07-01 false High-Altitude Counties III Appendix III to Part 1068 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR POLLUTION... Lander Lincoln Lyon Mineral Nye Pershing Storey Washoe White Pine STATE OF NEW MEXICO Bernalillo Catron...

With Portfolio in Hand. Validating the New Teacher Professionalism.

ERIC Educational Resources Information Center

Lyons, Nona, Ed.

This book suggests that portfolios can become a new kind of credential of competent and effective teachers. The book includes 5 parts with 16 chapters. Part 1, "Prologue," offers: (1) "Portfolio Possibilities: Validating a New Teacher Professionalism" (Nona Lyons) and (2) "Teacher Portfolios: A Theoretical Activity"…

Distribution of HLA-A,B alleles in 13 panels of blood donors in France.

PubMed

Prevost, P; Busson, M; Marcelli-Barge, A

1984-05-01

In this study, we analysed 13 samples of the French population--4147 non-related individuals living in Bordeaux, Brest, Caen, Dijon, Limoges, Lyon, Marseille, Nancy, Paris, Poitiers, Rennes, Strasbourg and Toulouse--all of whom were typed for 10 alleles of the HLA-A locus and 16 alleles of the HLA-B locus. The results showed a strong heterogeneity (chi 2 = 675.13 for 324 df, p less than 10(5)). A diagram has been drawn up, showing the matrix of genetic distances obtained thanks to the B2 of Balkrishnan & Sanghvi (1968). This diagram enables us to envisage the hypothesis of 6 homogeneous clusters. A partition of chi 2 was used to test this 6 luster hypothesis: Paris and Caen (p = 0.98); Nancy, Strasbourg (p less than 5%); Rennes, Brest (p less than 1%); Dijon, Lyon, Marseille (p = 0.89); Limoges, Poitiers (p = 0.18); Toulouse, Bordeaux (p less than 10(-5)). The heterogeneity within these clusters represents only 1/43 of the total heterogeneity.

Conditions of life and death of psychiatric patients in France during World War II: euthanasia or collateral casualties?

PubMed

Lemoine, Patrick; Stahl, Stephen M

2018-04-01

Between 1940 and 1944, an estimated 48,588 patients resident in French psychiatric hospitals died of starvation. Standard prisons, while facing similar problems, did not experience the same number of deaths by starvation, partly due to their ability to develop a black market for food and rations. Patients in psychiatric hospitals, on the other hand, were completely at the mercy of their doctors and the personnel in charge. At Hôpital du Vinatier, a psychiatric facility in Lyon, the mortality rate increased sharply from 1940 to 1944. In 1942, the worst year, 42% of patients died of hunger and exposure. In the end, more than 2,000 patients died at Vinatier. Was this due to a supposed lack of rations, or was it something more sinister? In Germany at the same time, tens of thousands of psychiatric patients died of purposeful starvation in psychiatric hospitals as part of the Nazi program of psychiatric euthanasia. Was the same thing occurring in Lyon?

[Comparison of genetic diversity (RAPD) of ex situ collections and natural populations of Naufraga balearica Constance & Cannon].

PubMed

Fridlender, A; Boisselier-Dubayle, M C

2000-04-01

Naufraga balearica Constance & Cannon (Hydrocotyloideae) cultivated in the Botanical Gardens of Lyon, Brest and Porquerolles stem from two or three shoots collected in Corsica in 1981. The genetic diversity of these plants was evaluated using RAPD markers (random amplified polymorphic DNA). It was compared with the diversity found in individuals collected from five natural sites in Majorca. Only a few patterns were present in the collections derived from the Corsican shoots. The plants kept in the Botanical Gardens appeared to be of clonal origin: most individuals (81%) showed a 'dominant pattern'. In contrast, nearly all individuals sampled in the natural populations of the Balearic Islands exhibited a unique pattern. The five populations appeared genetically distinct; the individuals probably resulted from cross-fertilizations. The cultivated Corsican plants from Lyon, Brest and Porquerolles appeared genetically closely related to the individuals sampled in the population of Cala San Vicente in Majorca. The spontaneity of this paleoendemic in Corsica was discussed.

Geology and occurrence of ground water in Lyon County, Minnesota

USGS Publications Warehouse

Rodis, Harry G.

1963-01-01

Large quantities of ground water are available from melt-water channels in the county. Moderate quantities, adequate for domestic and small industrial needs, are available from many of the small isolated deposits of sand and gravel in the till. Small quantities of ground water, adequate only for domestic supply, generally can be obtained from Cretaceous sandstone.

CONCLUSIONS ET RECOMMANDATIONS À L’ISSUE DE LA CONSULTATION DE L’OMS SUR LA LUTTE CONTRE LA CARENCE MARTIALE CHEZ LE NOURRISSON ET LE JEUNE ENFANT DANS LES PAYS D’ENDÉMIE PALUSTRE

PubMed Central

Allen, L.; Black, R.E.; Brandes, N.; Brittenham, G.; Chazot, G.; Chunming, C.; Crawley, J.; de Benoist, B.; Dalmiya, N.; Darnton-Hill, I.; Dewey, K.; El-Arifeen, S.; Fontaine, O.; Geissler, C.; Haberle, H.; Harvey, P.; Hasler, J.; Hershko, C.; Hurrell, R.; Juma, M.A.; Lönnerdal, B.; Lozoff, B.; Lynch, S.; Salgado, H. Martines; McLean, E.; Metz, J.; Oppenheimer, S.; Premji, Z.; Prentice, A.; Ramsan, M.; Ratledge, C.; Stoltzfus, R.; Tielsch, J.; Winachagoon, P.

2011-01-01

Cet article présentent les résultats d'une Consultation d'Experts dont l'objectif était d'évaluer l'efficacité et l'innocuité des suppléments de fer administrés aux nourrissons et aux jeunes enfants dans les zones d’endémie palustre, ainsi que les conséquences d’une telle mesure pour la santé publique. Les participants à cette Consultation, qui s’est déroulée à Lyon (France) les 12–14 juin 2006, se sont entendus sur plusieurs questions importantes concernant l’administration d’une supplémentation martiale aux nourrissons et aux jeunes enfants dans les zones d’endémie palustre. Les conclusions du présent rapport s’appliquent plus particulièrement aux pays où le paludisme est endémique. PMID:18630054

Psychiatric Diagnoses and Punishment for Misconduct: The Effects of PTSD in Combat-deployed Marines

DTIC Science & Technology

2010-10-25

between cohorts of veterans with and without mental illness discharged from inpatient units. Psychiatr Serv 2008, 59:178-83. 25. Koenen KC, Lyons MJ ...1991. 44. Edwards JE, Newell CE: Navy pattern-of-misconduct discharges: A study of potential racial effects (NPRDC-TR-94-11). San Diego, CA: Navy

Psychiatric Diagnoses and Punishment for Misconduct: The Effects of PTSD in Combat-Developed Marines

DTIC Science & Technology

2010-10-25

illness discharged from inpatient units. Psychiatr Serv 2008;59:178-83. 25. Koenen KC, Lyons MJ , Goldberg J, Simpson J, William WM, Toomey R, Eisen SA...Research and Development Center, 1991. 44. Edwards JE, Newell CE: Navy pattern-of-misconduct discharges: A study of potential racial effects (NPRDC-TR

Using and Evaluating Differential Modeling in Intelligent Tutoring and Apprentice Learning Systems.

DTIC Science & Technology

1987-01-01

medical diagnosis (Buchanan and Shortliffe, 1984); student hypothesis errors are discovered in the process of conducting a Socratic dialogue. Recent... Jose Mestre Pit-sb r h, PA 15213 Urbana, IL 61801 Department of Physics D- %iDHasbrouck Laboratory A; Jilr ieLaKin Dr. Don Lyon University of

77 FR 67837 - Callaway Plant, Unit 1; Application for Amendment to Facility Operating License

Federal Register 2010, 2011, 2012, 2013, 2014

2012-11-14

... methods: Federal Rulemaking Web site: Go to http://www.regulations.gov and search for Docket ID NRC-2012... search, select ``ADAMS Public Documents'' and then select ``Begin Web- based ADAMS Search.'' For problems... INFORMATION CONTACT: Carl F. Lyon, Project Manager, Office of Nuclear Reactor Regulation, U.S. Nuclear...

Learning Disabilities: Lifelong Issues.

ERIC Educational Resources Information Center

Cramer, Shirley C., Ed.; Ellis, William, Ed.

This book contains papers on learning disabilities based on presentations made at the "Summit on Learning Disabilities: A National Responsibility," held in September 1994. The first section provides an overview and includes "The State of Research" (G. Reid Lyon). The second section focuses on education and includes:…

A Computational Model of Spatial Visualization Capacity

DTIC Science & Technology

2008-03-07

GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 61102F 6. AUTHOR(S) Don Lyon; Glenn Gunzelmann; Kevin Gluck 5d. PROJECT NUMBER 2313 5e. TASK NUMBER AS...specialization in prefrontal cortex: Effects of verbalizability, imageability and meaning. Journal of Neurolinguistics , 16, 361–382. Diwadkar, V. A

77 FR 54890 - Foreign-Trade Zone 220-Sioux Falls, SD; Authorization of Production Activity; Rosenbauer America...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-06

... DEPARTMENT OF COMMERCE Foreign-Trade Zones Board [B-33-2012] Foreign-Trade Zone 220--Sioux Falls, SD; Authorization of Production Activity; Rosenbauer America, LLC/Rosenbauer South Dakota, LLC, (Emergency Vehicles/Firefighting Equipment), Lyons, SD On April 30, 2012, the Sioux Falls Development Foundation, grantee of FTZ 220, submitted a...

Fourteen-Day Subchronic Oral Toxicity Study of Nitroguanidine in Rats

DTIC Science & Technology

1988-06-01

Beckett , SGT Samuel S. Liu, BS, and SP4 Gary E. Mattison provided hematology support; SP4 Julius Harmon and Mary E. Lyons provided clinical...Count xlO6/^! xl03/|il White Blnod Cell Differential Neutro- Lympho- Eosino- Mono- phils cytes phils cytes % % % % 0 85D00308

The Effect of Restored and Native Oxbows on Hydraulic Loads of Nutrients and Stream Water Quality

EPA Science Inventory

The use of oxbow wetlands has been identified as a potential strategy to reduce nutrient transport from agricultural drainage tiles to streams in Iowa. In 2013 and 2014, a study was conducted in north central Iowa in a native oxbow in the Lyons Creek watershed and two reconstruc...

Ma ka Hana ka 'Ike (In the Work Is the Knowledge): Kaona as Rhetorical Action

ERIC Educational Resources Information Center

McDougall, Brandy Nalani; Nordstrom, Georganne

2011-01-01

Malea Powell's description of composition and rhetoric's scholarship on American Indian texts echoes assertions made by Scott Richard Lyons, who writes that while the literature of the past decade demonstrates the discipline's efforts at including Native ways of knowing in scholarly discussions and classroom curricula, representations of Native…

Interspecific nest parasitism by chukar on greater sage-grouse

USGS Publications Warehouse

Fearon, Michelle L.; Coates, Peter S.

2014-01-01

Nest parasitism occurs when a female bird lays eggs in the nest of another and the host incubates the eggs and may provide some form of parental care for the offspring (Lyon and Eadie 1991). Precocial birds (e.g., Galliformes and Anseriformes) are typically facultative nest parasites of both their own and other species (Lyon and Eadie 1991). This behavior increases a female’s reproductive success when she parasitizes other nests while simultaneously raising her own offspring. Both interspecific and conspecific nest parasitism have been well documented in several families of the order Galliformes, particularly the Phasianidae (Lyon and Eadie 1991, Geffen and Yom-Tov 2001, Krakauer and Kimball 2009). The Chukar (Alectoris chukar) has been widely introduced as a game bird to western North America from Eurasia and is now well established within the Great Basin from northeastern California east to Utah and north to Idaho and Oregon (Christensen 1996). Over much of this range the Chukar occurs with other phasianids, including the native Greater Sage-Grouse (Centrocercus urophasianus), within sagebrush (Artemisia spp.) steppe (Christensen 1996, Schroeder et al. 1999, Connelly et al. 2000). Chukar typically exploit a broader range of habitats than do sage-grouse, but both species use the same species of sagebrush and other shrubs for nesting cover (Christensen 1996, Schroeder et al. 1999). Chukar are known to parasitize nests of other individuals of their own species (Geffen and Yom-Tov 2001), but we are unaware of reported evidence that Chukar may parasitize nests of sage-grouse. Here we describe a case of a Chukar parasitizing a sage-grouse nest in the sagebrush steppe of western Nevada.

Overcoming the "Run" Response

ERIC Educational Resources Information Center

Swanson, Patricia E.

2013-01-01

Recent research suggests that it is not simply experiencing anxiety that affects mathematics performance but also how one responds to and regulates that anxiety (Lyons and Beilock 2011). Most people have faced mathematics problems that have triggered their "run response." The issue is not whether one wants to run, but rather…

Internship and Foreign Language Training: Blending Academic Study and Extra-Academic Experience.

ERIC Educational Resources Information Center

Iwamura, Susan Grohs

Student experiences in an exchange program linking the University of Hawaii and the Graduate School of Business in Lyon, France illustrate the positive impact of foreign internships. The students were enrolled in internship programs in travel industry management. The reports written by the students reveal that the experiences have affected the…

Collateral Damage and Communicable Disease with Particular Reference to Tactical Nuclear War in Europe.

DTIC Science & Technology

1978-10-31

incidence of communicable disease attrib- utable to the radiation exposure. Measles, chicken pox , etc., did occur but were within the normal range. 4.4...SMALLPOX MEXICO MILLIONS 50 1603 BUBONIC PLAGUE LONDON 34,000 14 1628 TYPHUS LYONS, FRANCE 60,000 1665 BUBONIC PLAGUE LONDON 100,000 27 1711 BUBONIC PLAGUE

Women Secondary Head Teachers: Alive and Well in Birmingham at the Beginning of the Twenty-First Century

ERIC Educational Resources Information Center

Fuller, Kay

2009-01-01

Far from being an "endangered species" (Edwards & Lyons, 1994), moving towards extinction, women secondary head teachers are alive and well in Birmingham. While the national picture in England and Wales showed 29.8 per cent of secondary head teachers were women in 2005, this research identifies extensive regional differences. In…

An In-Depth Exploration of the Effects of the Webcam on Multimodal Interactive Learning

ERIC Educational Resources Information Center

Codreanu, Tatiana; Celik, Christelle Combe

2012-01-01

Current research describes multimodal pedagogical communication of two populations of online teachers; trainee tutors (second year students of the Master of Arts in Teaching French as a Foreign Language at the university Lumiere-Lyon 2, France) and experienced teachers based in different locations (France, Spain and Finland). They all taught…

Issues/Higher Education/Institutional Research. NCAIR Proceedings. Fifth Annual Meeting of the North Carolina Association for Institutional Research (Asheville, North Carolina, November 2-3, 1977).

ERIC Educational Resources Information Center

Brown, Charles I., Ed.

Proceedings from the fifth annual meeting of the North Carolina Association for Institutional Research (NCAIR) focus on issues affecting higher education and the relationship of these issues to the institutional research function. Included are general session addresses by Charles A. Lyons and Dick Robinson that discuss the implications of Judge…

78 FR 52426 - Retail Commodity Transactions Under Commodity Exchange Act

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-23

... enacted to reduce risk, increase transparency, and promote market integrity within the financial system by... typical commercial practice in cash or spot markets for the commodity involved.\\11\\ \\10\\ 7 U.S.C. 2(c)(2..., LLP (GBT), and Rothgerber Johnson & Lyons LLP (RJL). \\17\\ National Energy Markets Association (NEM...

Current Developments in Language Testing. Anthology Series 25.

ERIC Educational Resources Information Center

Anivan, Sarinee, Ed.

The selection of papers on language testing includes: "Language Testing in the 1990s: How Far Have We Come? How Much Further Have We To Go?" (J. Charles Alderson); "Current Research/Development in Language Testing" (John W. Oller, Jr.); "The Difficulties of Difficulty: Prompts in Writing Assessment" (Liz Hamp-Lyons,…

Teaching the Bill of Rights. A Guide for Upper Elementary and Middle School Teachers.

ERIC Educational Resources Information Center

Lindquist, Tarry L.; And Others

To celebrate the Bicentennial of the United States Constitution, this curriculum illustrates the concepts of the Constitution and Bill of Rights through events and issues of the Pacific Northwest. The eight units of the curriculum include constitutional visions, the trial of Hershel C. Lyon: an environmental dilemma, comparison of rights around…

Observations on adult Agrilus planipennis on ash in Michigan

Treesearch

D. R. Lance; I. Fraser; V. C. Mastro

2007-01-01

Observations were carried out on adult emerald ash borers, Agrilus planipennis Fairmaire, on ash trees, Fraxinus spp., in park-like and field-edge settings in South Lyon, MI. Observations consisted of (1) counting beetles in various microhabitats; and (2) tracking behavior of individual beetles for periods of up to 15 min....

78 FR 78995 - Proposed Flood Hazard Determinations

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-27

... resolution process. SRPs are independent panels of experts in hydrology, hydraulics, and other pertinent..., Fountain City, IN 47341. Town of Greens Fork Town Hall, 12 South Water Street, Greens Fork, IN 47345. Town... Office, 212 Water Street, Lyons, MI 48851. Village of Muir Village Hall, 122 Superior Street, Muir, MI...

Tracking hydrothermal alteration and mineralization in rock-forming and accessory minerals from the Lyon Mountain Granite and related iron oxide apatite (IOA) ores from the Adirondack Mountains, New York State

NASA Astrophysics Data System (ADS)

Buchanan, A.; Hanchar, J. M.; Steele-MacInnis, M. J.; Crowley, J. L.; Valley, P. M.; Fisher, C. M.; Fedo, C.; Piccoli, P. M.; Fournelle, J.

2012-12-01

The Lyon Mountain granite (LMG) is located in the northeastern Adirondack Mountains in New York State and hosts several low-titanium iron oxide apatite (IOA) ore deposits. The ores are predominately hosted by perthite bearing granite, which has been extensively altered to albite and microcline granite by Na and K metasomatism. This alteration results in several distinct groups of rocks that are dominated by either K or Na addition and a group composed of mixed Na and K addition. The different groups of altered perthite also lie on a trend suggestive of addition of Fe to each, consistent with a secondary mineralization origin. Previous work showed that the host rocks of the IOA ores have zircon with ~1150 Ma cores and 1060-1050 Ma rims and whole grains. This study aims to further constrain the timing of LMG emplacement, subsequent hydrothermal alteration, and Fe mineralization through geochemical analysis of the major, minor, and accessory phases and geochronology of accessory phases. SIMS analyses of zircon from several of the IOA ores reveal at least two periods of growth after LMG magmatism, at 1039 +/- 4.4 Ma and 1016 +/- 7 Ma to 1000 +/- 9 Ma. In situ EMPA and LA-ICPMS trace element analyses of the zircon rims and cores reveal that in two samples the zircon rims are enriched in rare earth elements (REE) compared to their cores, potentially pointing to a hydrothermal origin. Apatite has unusually high REE and Y concentrations (some total REE2O3 > 20 wt. % oxide and up to 8 wt. % oxide Y2O3), as does titanite, which allowed for the in situ analysis of Sm-Nd in apatite and titanite by LA-MC-ICP-MS. Initial Nd isotopic composition of both ore and host rock apatite and host rock titanite are consistent with published Adirondack initial Nd whole rock data, suggesting a local source for REE in these ores. EMPA and LA-ICPMS trace-element analyses of the major rock-forming minerals indicate that the feldspar have undergone Na-metasomatism and are depleted in REEs

THE READABILITY OF SCIENCE TEXTBOOKS FOR ELEMENTARY SCHOOL.

ERIC Educational Resources Information Center

NEWPORT, JOHN F.

AN INVESTIGATION WAS MADE OF THE READABILITY LEVELS OF NINE CONTINUOUS SERIES OF ELEMENTARY SCHOOL SCIENCE TEXTBOOKS, GRADES 1-6. THE FOLLOWING SCIENCE SERIES WERE EVALUATED--ALLYN AND BACON, AMERICAN BOOK COMPANY, GINN, HARPER AND ROW, HEATH, LYONS AND CARNAHAN, MACMILLAN, SINGER, AND WINSTON. THE SPACHE FORMULA (SAFIER METHOD) WAS APPLIED TO…

Thirty-Day Results for the Kelly Air Force Base Compressed Work Week Survey

DTIC Science & Technology

1992-11-01

Gummer, B. All that stresses does not strain: Job satisfaction, morale and turnover. Administration in Social Work, 3, 489-494, 1979. 5. Ivancevich , J.M...and Lyon , H.L. The shortened workweek: A field experi- ment. Journal of Applied Psychology, 62 (1), 34-37, 1977. 6. Latick, J.C. and Foster, L.W

Frames of Reference for the Assessment of Learning Disabilities: New Views on Measurement Issues.

ERIC Educational Resources Information Center

Lyon, G. Reid, Ed.

This book offers 27 papers addressing critical issues in the assessment of students with all kinds of learning disabilities. Papers have the following titles and authors: "Critical Issues in the Measurement of Learning Disabilities" (G. Reid Lyon); "A Matrix of Decision Points in the Measurement of Learning Disabilities" (Barbara K. Keogh);…

How Relevant Are Science Curricula for Rural and Remote Students?

ERIC Educational Resources Information Center

Lyons, Terry; Quinn, Frances

2014-01-01

This paper reports findings from the Choosing Science study (Lyons & Quinn, 2010) indicating that Australian Year 10 students in small rural or remote areas tend to regard their science lessons as less relevant than do students in larger towns and cities. Specifically, those in small rural or remote schools were significantly more inclined…

75 FR 14594 - Environmental Impacts Statements; Notice of Availability

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-26

... Forest, Mono County, CA and Lyon, Douglas, and Mineral Counties, NV, Wait Period Ends: 04/26/2010.../ 2010, Contact: Douglas Gober, 208-476-4541. EIS No. 20100089, Draft EIS, STB, AK, Port MacKenzie Rail..., Richland, Benton County, WA, Comment Period Ends: 05/03/2010, Contact: Mary Beth Burandi, 888-829- 6347...

Impulse Response Operators for Structural Complexes

DTIC Science & Technology

1990-05-12

systems of the complex. The statistical energy analysis (SEA) is one such a device [ 13, 14]. The rendering of SEA from equation (21) and/or (25) lies...Propagation.] 13. L. Cremer, M. Heckl, and E.E. Ungar 1973 Structure-Borne Sound (Springer Verlag). 14. R. H. Lyon 1975 Statistical Energy Analysis of

Conservatism and the Culture Wars: The View from the College Classroom

ERIC Educational Resources Information Center

Manuel, Jeffrey T.

2012-01-01

What does it mean to engage deeply with conservatism in the classroom? Are classroom politics determined by a professor's personal political opinions or by course content? Historian Paul Lyons takes up these timely questions in his slim but intriguing book "American Conservatism: Thinking It, Teaching It." The book is divided in two…

Cluster analysis of social and environment inequalities of infant mortality. A spatial study in small areas revealed by local disease mapping in France

PubMed Central

Padilla, Cindy M.; Deguen, Severine; Lalloue, Benoit; Blanchard, Olivier; Beaugard, Charles; Troude, Florence; Navier, Denis Zmirou; Vieira, Verónica M.

2014-01-01

Mapping spatial distributions of disease occurrence can serve as a useful tool for identifying exposures of public health concern. Infant mortality is an important indicator of the health status of a population. Recent literature suggests that neighborhood deprivation status can modify the effect of air pollution on preterm delivery, a known risk factor for infant mortality. We investigated the effect of neighborhood social deprivation on the association between exposure to ambient air NO2 and infant mortality in the Lille and Lyon metropolitan areas, north and center of France, respectively, between 2002 and 2009. We conducted an ecological study using a neighborhood deprivation index estimated at the French census block from the 2006 census data. Infant mortality data were collected from local councils and geocoded using the address of residence. We generated maps using generalized additive models, smoothing on longitude and latitude while adjusting for covariates. We used permutation tests to examine the overall importance of location in the model and identify areas of increased and decreased risk. The average death rate was 4.2‰ and 4.6‰ live births for the Lille and Lyon metropolitan areas during the period. We found evidence of statistically significant precise clusters of elevated infant mortality for Lille and an east-west gradient of infant mortality risk for Lyon. Exposure to NO2 did not explain the spatial relationship. The Lille MA, socioeconomic deprivation index explained the spatial variation observed. These techniques provide evidence of clusters of significantly elevated infant mortality risk in relation with the neighborhood socioeconomic status. This method could be used for public policy management to determine priority areas for interventions. Moreover, taking into account the relationship between social and environmental exposure may help identify areas with cumulative inequalities. PMID:23563257

From Internet of Things to Smart Data for Smart Urban Monitoring

NASA Astrophysics Data System (ADS)

Gastaud, E.

2017-09-01

Cities are facing some of the major challenges of our time: global warming, pollution, waste management, energy efficiency. The territory of the Metropolis of Lyon, France, which brings together 59 municipalities, for a total of 1.3 million inhabitants, has launched a smart city policy aimed, among other things, at finding solutions for these issues. The data platform set up in 2013 is one of the cornerstones of this policy. In this context, the Metropolis of Lyon is deploying solutions that will enable, through the collection of new data, to implement monitoring and action tools in several fields. As part of a European innovation project called "bIoTope", focused on the development of new services based on the Internet of Things, a multidisciplinary team is implementing a system to mitigate the effects of global warming in the city. Thanks to various connected objects allowing a true monitoring of the trees, and by using different data sources, an automatic and intelligent irrigation system is developed. In the field of waste management, several hundred containers in which the inhabitants throw away their used glass for recycling will soon be equipped with fill rate sensors. The main objective is to have this network of sensors interact easily with the container collection trucks. Expected results are an optimization of the collection, thus less fuel consumed, less noise, less traffic jam. The Metropolis of Lyon also participates in the "Smarter Together" project, focused on the development of intelligent duplicable solutions for cities, in the field of energy. A digital tool for analysing consumption and energy production at the level of a neighbourhood is currently being developed. This requires both interfaces with multiple partners, the development of a data model reflecting the reality of the terrain, from the sensors to the buildings, and the implementation of a visualization tool.

Air pollution, health and social deprivation: A fine-scale risk assessment.

PubMed

Morelli, Xavier; Rieux, Camille; Cyrys, Josef; Forsberg, Bertil; Slama, Rémy

2016-05-01

Risk assessment studies often ignore within-city variations of air pollutants. Our objective was to quantify the risk associated with fine particulate matter (PM2.5) exposure in 2 urban areas using fine-scale air pollution modeling and to characterize how this risk varied according to social deprivation. In Grenoble and Lyon areas (0.4 and 1.2 million inhabitants, respectively) in 2012, PM2.5 exposure was estimated on a 10×10m grid by coupling a dispersion model to population density. Outcomes were mortality, lung cancer and term low birth weight incidences. Cases attributable to air pollution were estimated overall and stratifying areas according to the European Deprivation Index (EDI), taking 10µg/m(3) yearly average as reference (counterfactual) level. Estimations were repeated assuming spatial homogeneity of air pollutants within urban area. Median PM2.5 levels were 18.1 and 19.6μg/m(3) in Grenoble and Lyon urban areas, respectively, corresponding to 114 (5.1% of total, 95% confidence interval, CI, 3.2-7.0%) and 491 non-accidental deaths (6.0% of total, 95% CI 3.7-8.3%) attributable to long-term exposure to PM2.5, respectively. Attributable term low birth weight cases represented 23.6% of total cases (9.0-37.1%) in Grenoble and 27.6% of cases (10.7-42.6%) in Lyon. In Grenoble, 6.8% of incident lung cancer cases were attributable to air pollution (95% CI 3.1-10.1%). Risk was lower by 8 to 20% when estimating exposure through background stations. Risk was highest in neighborhoods with intermediate to higher social deprivation. Risk assessment studies relying on background stations to estimate air pollution levels may underestimate the attributable risk. Copyright © 2016 Elsevier Inc. All rights reserved.

A Tradition Unlike Any Other: Research on the Value of an Honors Senior Thesis

ERIC Educational Resources Information Center

Banks, H. Kay

2016-01-01

An honors senior thesis introduces students into a world of scholarship and professional activity in a way that no single course, either semester- or year-long, can do (Anderson, Lyons, and Weiner). Many honors educators consider honors thesis work to be the defining honors experience. For graduate schools, employers, and the students themselves,…

What's Been Cooking in the Type Kitchen?

ERIC Educational Resources Information Center

Banks, Colin

1999-01-01

Presents a critical report on the events of the Association Typographique Internationale's 1998 conference held in Lyons, France. Discusses papers presented and the state of the field of typography. Notes that, although attending the conference was expensive, the real reward for the author and students he spoke to was the chance to socialize with…

18. Readiness Crew Building interior, lower level corridor. This corridor ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

18. Readiness Crew Building interior, lower level corridor. This corridor is located in the southwest side of the building and runs from southeast to northwest; view looking northwest from the exit door at the southeast end. Lyon - Whiteman Air Force Base, Bomber Alert Facility S-6, 1300 Alert Road, Knob Noster, Johnson County, MO

Putting the Pieces Together

ERIC Educational Resources Information Center

Thomson, Alastair

2007-01-01

Recent policy reports by Lord Leitch and Sir Michael Lyons on educational skills and corresponding government spending raise the question of how a demand-led system for adult skills led by employers can operate concurrent with intertwined policies driven by different factors. There is also the need to integrate with regional policy and policies…

Genetics Home Reference: KBG syndrome

MedlinePlus

... and 16q24.3 microdeletion. Eur J Med Genet. 2015 Feb;58(2):86-94. doi: 10.1016/j.ejmg.2014.11.003. Epub 2014 Nov 20. Citation on PubMed Kleyner R, Malcolmson J, Tegay D, Ward K, Maughan A, Maughan G, Nelson L, Wang K, Robison R, Lyon GJ. KBG syndrome involving ...

Progressively Fostering Students' Chemical Information Skills in a Three-Year Chemical Engineering Program in France

ERIC Educational Resources Information Center

Gozzi, Christel; Arnoux, Marie-Jose´; Breuzard, Jere´my; Marchal, Claire; Nikitine, Clémence; Renaudat, Alice; Toulgoat, Fabien

2016-01-01

Literature searches are essential for scientists. Thus, courses on how to do a good literature search have been integrated in studies at CPE Lyon for many years. Recently, we modified our pedagogical approach in order to initiate students progressively in the search for chemical information. In addition, this new teaching organization is now based…

Getting to Know Your Students and an Educational Ethic of Care

ERIC Educational Resources Information Center

Hawk, Thomas F.

2017-01-01

In the 10 years since Hawk and Lyons published, "Please Don't Give Up on Me: When Faculty Fail to Care" in "Journal of Management Education," much has changed about the nature of pedagogical caring, relational learning, and the instructor-student relationship per se. The landscape of expectations for the type and depth of…

Quelques aspects du folklore de la region Roannaise autour de 1950 (Some Aspects of Folklore of the Roanne Region about 1950).

ERIC Educational Resources Information Center

Long, Jacqueline

1971-01-01

This article examines several aspects of folklore characteristic of the region of Roanne, France, during the 1950's. The town of Roanne, located between Clermont Ferrand and Lyon on the Loire River, is described in terms of its festive activities during serveral key holidays. The erosion of various customs and traditions, an inevitable result of…

Effects of Webcams on Multimodal Interactive Learning

ERIC Educational Resources Information Center

Codreanu, Tatiana; Celik, Christelle Combe

2013-01-01

This paper describes the multimodal pedagogical communication of two groups of online teachers; trainee tutors (second year students of the Master of Arts in Teaching French as a Foreign Language at the University Lumiere-Lyon 2) and experienced teachers based in different locations (France, Spain and Finland). They all taught French as a Foreign…

Integrating social science into forestry in the wildland/urban interface

Treesearch

Jeffrey J. Brooks; Hannah Brenkert; Judy E. Serby; Joseph G. Champ; Tony Simons; Daniel R. Williams

2006-01-01

A different kind of storm--neither fire nor wind--brought 60 forestry practitioners who work in wildfire risk prevention and several social science researchers together near Lyons, CO. Brainstorm. This unique retreat--a meeting of the minds--commingled these two groups to share and tackle ideas concerning social issues that shape decisions and behaviors regarding...

Sequence Search and Comparative Genomic Analysis of SUMO-Activating Enzymes Using CoGe.

PubMed

Carretero-Paulet, Lorenzo; Albert, Victor A

2016-01-01

The growing number of genome sequences completed during the last few years has made necessary the development of bioinformatics tools for the easy access and retrieval of sequence data, as well as for downstream comparative genomic analyses. Some of these are implemented as online platforms that integrate genomic data produced by different genome sequencing initiatives with data mining tools as well as various comparative genomic and evolutionary analysis possibilities.Here, we use the online comparative genomics platform CoGe ( http://www.genomevolution.org/coge/ ) (Lyons and Freeling. Plant J 53:661-673, 2008; Tang and Lyons. Front Plant Sci 3:172, 2012) (1) to retrieve the entire complement of orthologous and paralogous genes belonging to the SUMO-Activating Enzymes 1 (SAE1) gene family from a set of species representative of the Brassicaceae plant eudicot family with genomes fully sequenced, and (2) to investigate the history, timing, and molecular mechanisms of the gene duplications driving the evolutionary expansion and functional diversification of the SAE1 family in Brassicaceae.

Methods for monitoring the effects of grazing management on bank erosion and channel morphology, Fever River, Pioneer Farm, Wisconsin, 2004

USGS Publications Warehouse

Peppler, Marie C.; Fitzpatrick, Faith A.

2005-01-01

Bank erosion is a natural process that occurs in meandering streams (Leopold and others, 1964); however, in the Midwestern United States, historical and present agricultural activities in uplands, riparian areas, and channels have increased erosion (Waters, 1995; Lyons and others, 2000; Simon and Rinaldi, 2000; and Knox, 2001). Reducing streambank erosion is important because sediment carried by streams has adverse environmental effects; for example, sediment carried by streams is a major source of phosphorus (Waters, 1995). Continuous cattle grazing in riparian areas may increase local erosion processes in a meandering stream by removal or trampling of bank vegetation, which in turn affects channel morphology, water chemistry, and fish and aquatic-insect habitat (Kauffman and Krueger, 1984; Fitch and Adams, 1998). However, studies of livestock exclusion from riparian corridors have shown mixed results in reducing bank erosion (Trimble, 1994; Sarr, 2002). Some studies have shown reduced bank erosion after row-cropped or continuously grazed riparian areas are converted to managed grazing (see inset box) (Lyons and others, 2000; Sovell and others, 2000; and Zaimes and others, 2004).

Cardiac conductive disturbance in patients with polycystic ovary syndrome.

PubMed

Huang, Jen-Hung; Tsai, Jen-Chen; Hsu, Ming-I; Chen, Yi-Jen

2010-12-01

Polycystic ovary syndrome (PCOS) is the most common endocrine abnormality of reproductive-aged women and increases the risk of cardiovascular disease. However, the effects of PCOS on electrocardiograms (ECGs) are not fully elucidated. The aim of this study was to evaluate the characteristics of ECGs in patients with PCOS. This study included 24 patients with PCOS and 12 patients without PCOS. The heart rate, PR interval, QRS duration, Sokolow-Lyon voltage (SV1 + RV5/6), Cornell voltage (RaVL + SV3), QT interval and QTc interval were measured in 12-lead ECGs. The QRS duration was wider in patients with PCOS than those without PCOS (91 ± 8 vs. 81 ± 10 ms, p < 0.05). The heart rate, PR interval, Sokolow-Lyon voltage, product of the QRS duration times Cornell voltage combination, QT interval, QTc interval, QT dispersion and QTc dispersion were similar between the two groups. PCOS is associated with a widening QRS duration, which may contribute to its increased cardiovascular risks.

[Integrate the surgical hand disinfection as a quality indicator in an operating room of urology].

PubMed

Francois, M; Girard, R; Mauranne, C C; Ruffion, A; Terrier, J E

2017-12-01

The surgical hand disinfection by friction (SDF) helps to reduce the risk of surgical site infections. For this purpose and in order to promote good compliance to quality care, the urology service of Centre Hospitalier Lyon Sud achieved a continuous internal audit to improve the quality of the SDF. An internal audit executed by the medical students of urology was established in 2013. The study population was all operators, instrumentalists and operating aids of urology operating room (OR). Each student realized 5-10 random observations, of all types of professionals. The criteria measured by the audit were criteria for friction. The evolution of indicators was positive. Particularly, the increasing duration of the first and second friction was statistically significant during follow-up (P=0.001). The total duration of friction shows a similar trend for all professionals. The surgical hand disinfection by friction in the urology OR of the Centre Hospitalier Lyon Sud has gradually improved over the iterative audits. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

Control of the frequency of the (2,0) mode of liquid bridges using active electrostatic fields

NASA Astrophysics Data System (ADS)

Wei, Wei; Thiessen, David B.; Marston, Philip L.

2004-11-01

Active control of radial electrostatic fields was previously used to suppress the growth of the Plateau-Rayleigh instability in long liquid bridges in a Plateau tank [1] and (for bridges in air) in low gravity [2]. In the present research we use a Plateau tank bridge system having unusually low damping to explore the shift in the (2,0) mode frequency introduced by amplitude feedback for naturally stable bridges. The shift in the mode frequency is the result of the active stiffening of the bridge through the application of the appropriate Maxwell stress projection proportional to the model amplitude. The technique may be important for reducing the response of capillary systems (such as liquid bridges) to ambient vibrations for situations where a spectral peak of the excitation lies close to the natural frequency of an unstiffened mode. [1] M. J. Marr-Lyon, D. B. Thiessen, F. J. Blonigen, and P. L. Marston, Phys. Fluids 12, 986-995 (2000). [2] D. B. Thiessen, M. J. Marr-Lyon, and P. L. Marston, J. Fluid Mech. 457, 285-294 (2002).

The Fizeau Interferometer Testbed

DTIC Science & Technology

2003-03-01

Institute, Jay Rajagopal and Ron Allen; and at the CfA, Margarita Karovska , for their contribu- tions to the development of the testbed and the Stellar...2000. [2] K.G. Carpenter, C.J. Schrijver, R.G. Lyon, L.G. Mundy, R.J. Allen, J.T. Armstrong, W.C. Danchi, M. Karovska , J. Marzouk, L.M. Mazzuca, D

Perspectives from Former Executives of the DOD Corporate Research Laboratories

DTIC Science & Technology

2009-03-01

Research Laboratory (NRL) in Washington, DC; and the Air Force Research Laboratory ( AFRL ) in Dayton, Ohio respectively. These individuals are: John Lyons...13 Vincent Russo and the Air Force Research Laboratory The Air Force Research Laboratory ( AFRL ) was activated in 1997. Prior to the creation of... AFRL , the Air Force conducted its research at four major

View west of the James and Lucy Alexander gravestone and ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

View west of the James and Lucy Alexander gravestone and family plot among other demarcated family plots in the Female Union Band Cemetery. - Mount Zion Cemetery/ Female Union Band Cemetery, Bounded by 27th Street right-of-way N.W. (formerly Lyons Mill Road), Q Street N.W., & Mill Road N.W., Washington, District of Columbia, DC

Cahiers linguistiques d'Ottawa: 2, ii, 1972 (Ottawa Notebooks on Linguistics: Vol. 2, No. 2, 1972).

ERIC Educational Resources Information Center

Ottawa Univ. (Ontario). Dept. of Linguistics and Modern Languages.

This issue contains five articles dealing with several aspects of linguistic theory. The first, "Origine et evolution de la notion de 'situation' de 'l'Ecole linguistique de Londres': de Malinowski a Lyons," examines the origin and meaning of the concept of "situation" in articles by the London school of linguists. The second, "Some Aspects of a…

Zebrafish Model of NF1 for Structure-Function Analysis, Mechanisms of Glial Tumorigenesis, and Chemical Biology

DTIC Science & Technology

2013-05-01

Feng Guo1, Shuning He1, Marc A. Wolman2, Michael Granato2, Nathan D. Lawson4, Scot A. Wolfe4, Seok-Hyung Kim5, Lilianna Solnica-Krezel6, John P...gliomas. J. Neuropathol. Exp. Neurol. 63, 499- 509. Lyons, D. A., Pogoda, H. M., Voas, M. G., Woods , I. G., Diamond, B., Nix, R., Arana, N., Jacobs

America's Star Libraries, 2010: Top-Rated Libraries

ERIC Educational Resources Information Center

Lyons, Ray; Lance, Keith Curry

2010-01-01

The "LJ" Index of Public Library Service 2010, "Library Journal"'s national rating of public libraries, identifies 258 "star" libraries. Created by Ray Lyons and Keith Curry Lance, and based on 2008 data from the IMLS, it rates 7,407 public libraries. The top libraries in each group get five, four, or three stars. All included libraries, stars or…

Rural High School Students' Attitudes towards School Science

ERIC Educational Resources Information Center

Lyons, Terry; Quinn, Frances

2012-01-01

This paper reports findings from an Australian survey of Year 10 students (N=3759) indicating that those in small rural and remote areas tend to enjoy school science significantly less than their peers in larger towns and cities (Lyons & Quinn, 2010). The study also found that rural and remote students were less inclined than those in other…

Enhancing EFL Learners' Writing Skill via Journal Writing

ERIC Educational Resources Information Center

Tuan, Luu Trong

2010-01-01

"Frequently accepted as being the last language skill to be acquired for native speakers of the language as well as for foreign/second language learners" (Hamp-Lyons and Heasly, 2006: 2), English writing, for a number of EFL learners, appears to be challenging. This paper sought to investigate if learners can grow out of the writing…

Turkish Adaptation of Questionnaire on Attitudes towards Engineers and Scientists

ERIC Educational Resources Information Center

Ergün, Aysegül; Balçin, Muhammed Dogukan

2017-01-01

The aim of this research was to present the Turkish adaptation of the survey for Middle-School Students' Attitudes toward Engineers and Scientists prepared by Lyons, Fralick and Kearn (2009) 32 items in a 5-point Likert type scale. The questionnaire was administered to 707 students receiving education in the fifth, sixth, seventh and eighth grades…

Evaluating Leadership Coaching: A Review and Integrated Framework

DTIC Science & Technology

2008-01-01

California, San Francisco . Goldsmith, M. & Lyons, L. (2005). Coaching for leadership: The practice of leadership coaching from the world’s...greatest coaches. San Francisco : Pfeiffer. Goldstein, I. L., & Ford, J. K. (2002). Training in organizations: Needs assessment, development, and...techniques (pp. 139-158). San Francisco : Jossey-Bass. *Kampa-Kokesch, S. (2001). Executive coaching as an individually tailored consultation intervention

European Scientific Notes. Volume 37, Numbers 12.

DTIC Science & Technology

1983-12-01

Hamburg during August. This article highlights some of the papers dealing with oceano- graphy, geology, and geophysics. ENERGY Egypt’s Energy Crisis...little progress in developing alternative sources of energy . ENGINEERING Leeds-Lyon Tribology Conference ................................. Harold’G...probe the structure of the electric field in collective ion acceleration experiments. Energy -Transfer Processes in Condensed Matter

Students to Race Solar-Powered Model Cars

Science.gov Websites

hotel and the NREL Visitors Center. The SERF is the silver-colored building one-eighth mile past the teams Eagle Valley Middle School Two teams Fountain Middle School One team Hayden Middle School Two teams Kunsmiller Middle School One team Little Elementary Two teams Lyons Middle School Two teams Maple

The Construct of State-Level Suspicion A Model and Research Agenda for Automated and Information Technology (IT) Contexts

DTIC Science & Technology

2013-08-01

Explaining and Predicting the Impact of Branding Alliances and Web Site Quality ...on Initial Consumer Trust of e - Commerce Web Sites . Journal of Management Information Systems, 24, 199-224. Lyons, J., Stokes, C., Eschleman, K...Organizations. Academy of Management Journal, 38, 24-59. McKnight, D., Choudhury, V., & Kacmar, C. (2002). The Impact of Initial Consumer Trust

Adaptability of selected tree species planted in Hawaii forests

Treesearch

Robert E. Nelson; Thomas H. Schubert

1972-01-01

Many tree species have been introduced into Hawaii from around the world (Bryan and Walker i962, Hillebrand 1965, St. John 1973). Trial introductions of new species for various forestry purposes began in the 19th century and are still continuing. Walker (1887), Judd (1915); Lyon (1929), Zschokke (1930), Bryan (1947), and Whitesell (1971, 1974), among others, have...

On Being Imaginative, Resilient, and a Good Ancestor: Excerpts from Graduation Speeches

ERIC Educational Resources Information Center

Tully, Susannah, Comp.

2008-01-01

This article presents excerpts from this year's graduation speeches. These are from (1) J.K. Rowling, author, at Harvard University; (2) Mary E. Lyons, president of the University of San Diego, at the College of St. Catherine; (3) Samantha Power, journalist and professor of public policy at Harvard University, at Pitzer College; (4) E.J. Dionne,…

Kitchen Gardens: Contexts for Developing Proportional Reasoning

ERIC Educational Resources Information Center

Hilton, Annette; Hilton, Geoff; Dole, Shelley; Goos, Merrilyn; O'Brien, Mia

2013-01-01

It is great to see how the sharing of ideas sparks new ideas. In 2011 Lyon and Bragg wrote an "Australian Primary Mathematics Classroom" (APMC) article on the mathematics of kitchen gardens. In this article the authors show how the kitchen garden may be used as a starting point for proportional reasoning. The authors highlight different…

Europe/Latin America Report Science and Technology.

DTIC Science & Technology

1997-01-15

Partners: Mr. W. Horak Siemens A.G. KO AP 313 Otto Hahn Ring 6 D-8000München 83 Tel: 49-89-72223728 Tlx: 521090 Fax: 49-89-63647140 Siemens A.G...operate the equipment, Dr Joao Renato Pinho of the Adolfo Lutz Institute is pursuing studies in molecular hybridization at the University of Lyons, in

["There can be no unnecessary risks"].

PubMed

Ledesma, Enrique

2015-01-01

The psychoanalytical point of view regarding the notion of risks helps us to understand the concept of transference and counter transference. Practice analysis groups provide an opportunity for collective discussion and the sharing of experience of clinical situations. Interview with Didier Gauchy, a psychiatrist-psychoanalyst in Lyon. Copyright © 2015 Elsevier Masson SAS. All rights reserved.

Analysis of a Balanced Breech System for the M1A1 Main Gun System Using Finite Element Techniques

DTIC Science & Technology

1994-11-01

completion, this endeavor would not have been possible. The authors would also like to thank Robert Kaste and Dave Lyon of ARL for reviewing and...394) A BARAN (394) AMSRL-WT-WB/ F BRANDON (120) W D’AMICO (120) AMSRL-WT-WC/J ROCCHIO (120) AMSRL-WT-WD/ A ZIELINSKI (120) J POWELL (120) AMSRL-WT-WE

Effects of roads on elk: implications for management in forested ecosystems.

Treesearch

Mary M. Rowland; Michael J. Wisdom; Bruce K. Johnson; Mark A. Penninger

2004-01-01

The effects of roads on both habitat and population responses of elk (Cervus elaphus) have been of keen interest to foresters and ungulate biologists for the last half century. Increased timber harvest in national forests, beginning in the 1960s, led to a proliferation of road networks in forested ecosystems inhabited by elk (Hieb 1976, Lyon and...

An Analysis of Ethics Laws, Compliance with Ethical Standards, and Ethical Core Competency within the Department of the Army

DTIC Science & Technology

2016-06-15

laws and ethical principles above private gain. (2) Employees shall not hold financial interests that conflict with the conscientious...applying ethical principles to decision-making. We analyze the DA ethics training courses, policies, and procedures. The project explores the...leveraging the Enterprises buying power to obtain goods and services more efficiently. Ms. Lyons earned her Bachelor of Science degree in Accounting in

A District Approach to Countering Afghanistan’s Insurgency

DTIC Science & Technology

2009-12-01

actualization. Abraham Maslow , A Theory of Human Motivation, 1943, http://psychclassics.yorku.ca/ Maslow /motivation.htm (accessed October 29, 2009...Lyon Press, 2002. Maslow , Abraham . A Theory of Human Motivation, 1943. http://psychclassics.yorku.ca/ Maslow /motivation.htm (accessed October 29...established village and district political hierarchies may effectively deny insurgents sanctuary, critical resources, and serve to isolate and separate the

Whole Language in ABLE--Just Do It! Research to Practice.

ERIC Educational Resources Information Center

Baker, Karen

The whole language approach was used with a "well" or successful adult basic and literacy education (ABLE) group. Literature was chosen as a curriculum for which group work could be devised that was geared to all levels of students. The book used was "Choices" by George Ella Lyon, a book of short stories written by characters who live in a small…

Social Media Analytics: A New Approach for Cyberspace Enabled Understanding of Operational Environments

DTIC Science & Technology

2013-12-10

NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT NUMBER Major Sean Lyons 5e. TASK NUMBER 5f. WORK...Advance Research Projects Agency DOD Department of Defense FM Field Manual IC Intelligence Community IO Information Operations IP Internet...Utah, Central Intelligence Agency funding of the Recorded Future Company, and Defense Advanced Research Projects Agency, XDATA project . 2

Why Story Circle Matters

ERIC Educational Resources Information Center

Lyon, George Ella

2016-01-01

If adult attention is screen scrambled, what about kids, whose brains are still developing? In a world where we are over stimulated and hyperlinked-in we are deprived of the kind of time with a person or experience that deepens and sustains us. Here, poet laureate George Ella Lyon writes that the story circle can be such an experience. A school…

America's Star Libraries: Top-Rated Libraries

ERIC Educational Resources Information Center

Lance, Keith Curry; Lyons, Ray

2009-01-01

"Library Journal"'s national rating of public libraries, the "LJ" Index of Public Library Service 2009, Round 2, identifies 258 "star" libraries. Created by Keith Curry Lance and Ray Lyons and based on 2007 data from the IMLS, it rates 7,268 public libraries. The top libraries in each group get five, four, or three stars. All included libraries,…

Influenza Vaccine Effectiveness Among US Military Basic Trainees, 2005-06 Season

DTIC Science & Technology

2007-04-01

receive mandatory influenza vaccination , either the trivalent inactivated influenza vaccine by injection (FluZone, Sanofi Pasteur, Lyon, France) or...Naval Health Research Center Influenza Vaccine Effectiveness Among US Military Basic Trainees, 2005–06 Season J. K. Strickler A. W...Naval Health Research Center 140 Sylvester Road San Diego, California 92106 Influenza Vaccine Effectiveness among US Military Basic Trainees, 2005

Accuracy criteria voltage electrocardiography left ventricular hypertrophy to distinguish types of left ventricular hypertrophy geometry

NASA Astrophysics Data System (ADS)

Tumbur, O.; Safri, Z.; Hassan, R.

2018-03-01

Different types of left ventricular hypertrophy geometry are associated with different risk of cardiovascular disease. The purpose of this study was to determine the role of various ECG voltages of LVH to distinguish the type of LVH geometry. A cross-sectional study from June to November 2015, 100 patients in Adam Malik Hospital Medan. The result of LVH ECG criteria of Sokolow-Lyon was not met then obtained normal left ventricular geometry with 60% sensitivity, 72.22% specificity, and 71% accuracy. The eccentric type of LVH is obtained when the Cornel Voltage is not met; the sensitivity is 25%, specificity 71.88%, and 55% accuracy. Concentric geometric hypertrophy when the RV6/V5> 1 ratio is satisfied, the sensitivity is 55.56%, specificity 56.36%, and 56% accuracy. The RV6/V5>1 ratio was not met, the concentric geometry type of hypertrophy remodeling was determined with a sensitivity of 55.56%, specificity 49.45%, and 50% accuracy. Conclusions, various LVHECG criteria distinguish the type of LVH geometry. Sokolow-Lyon and Cornel Voltage sensitivity and specificity are better than the RV6/V5 ratio.

Snapping turtles (Chelydra serpentina) as bioindicators in Canadian areas of concern in the Great Lakes Basin. 1. Polybrominated diphenyl ethers, polychlorinated biphenyls, and organochlorine pesticides in eggs.

PubMed

De Solla, S R; Fernie, K J; Letcher, R J; Chu, S G; Drouillard, K G; Shahmiri, S

2007-11-01

We examined the concentrations and spatial patterns of congeners of PBDEs, PCBs, and organochlorine pesticides in snapping turtle (Chelydra serpentina) eggs from Areas of Concern (AOCs) on the Canadian shores of Lake Ontario, St. Lawrence River, and connecting channels. Eggs from Lyons Creek (Niagara River AOC) reflected a local PCB source over a range of 7.5 km (3.2-10.8) from the Welland Canal. PCB contamination in eggs declined with increasing distance from the Welland Canal, whereas the relative contribution of congeners associated with Aroclor 1248/1254 increased with sigma PCB concentrations. Compared to turtle eggs from other sites in Lake Erie and Lake Ontario, eggs from Lyons Creek and Snye Marsh had PCB congener patterns that reflected a strong contribution from Aroclor 1254. PCBs in the eggs were associated with industrial sources and reflected the composition of different Aroclor technical mixtures. Organochlorine pesticides in eggs tended to be highest at Hamilton Harbour and Bay of Quinte AOCs, and were dominated by DDE, sigma chlordane, and mirex. In contrast, PBDE congener patterns in turtle eggs resembled PentaBDE technical formulations regardless of absolute concentrations or location, and were largely associated with urban environments.

A Spatial Perspective of Droughts and Pluvials in the Tropics and their Relationships to ENSO in CMIP5 Model Simulations

NASA Astrophysics Data System (ADS)

Perez Arango, J. D.; Lintner, B. R.; Lyon, B.

2016-12-01

Although many aspects of the tropical response to ENSO are well-known, the spatial characteristics of the rainfall response to ENSO remain relatively unexplored. Moreover, in current generation climate models, the spatial signatures of the ENSO tropical teleconnection are more uncertain than other aspects of ENSO variability, such as the amplitude of rainfall anomalies. Following the approach of Lyon (2004) and Lyon and Barnston (2005), we analyze here integrated measures of the spatial extent of drought and pluvial conditions in the tropics and their relationship to ENSO in observations as well as simulations of Phase 5 of the Coupled Model Intercomparison Project (CMIP5) with prescribed SST forcing. We compute diagnostics including the model ensemble-means and standard deviations of moderate, intermediate, and severe droughts and pluvials and the lagged correlations with respect to ENSO-based SST indices like NINO3. Overall, in a tropics-wide sense, the models generally capture the areal extent of observed droughts and pluvials and their phasing with respect to ENSO. However, at more local scales, e.g., tropical South America, the simulated metrics agree less strongly with observations, underscoring the role of errors in the spatial patterns of ENSO-induced rainfall anomalies.

Rotationally inelastic collisions of He and Ar with NaK: Theory and Experiment

NASA Astrophysics Data System (ADS)

Price, T. J.; Towne, A. C.; Richter, K.; Jones, J.; Hickman, A. P.; Huennekens, J.; Faust, C.; Malenda, R. F.; Ross, A. J.; Crozet, P.; Talbi, D.; Forrey, R. C.

2016-05-01

Rotationally inelastic thermal collisions of NaK A1Σ+ molecules with He and Ar have been studied at Lehigh and Lyon. In both laboratories, a pump laser excites a particular ro-vibrational level A1Σ+ (v , J). Strong transitions from the pumped (v , J) level and weaker transitions from collisionally-populated levels (v ,J' = J + ΔJ) occur. Ratios of line intensities yield information about population and orientation transfer. At Lyon, we also identify v changing collisions. A strong propensity for ΔJ = even transitions is observed for He and Ar. Theoretical calculations are underway; we've calculated He-NaK and Ar-NaK potential surfaces using GAMESS and performed coupled channel scattering calculations for JM -->J'M' transitions. Semiclassical formulas for the cross sections have been obtained and agree well with our quantum mechanical calculations. Using the vector model, where J precesses with polar angle θ about the z-axis, we derived the distribution of final polar angles θ' and final M' states. We identify a special case where the θ' distribution is a Lorentzian centered at θ. Work supported by NSF, XSEDE and CNRS (PICS).

Active damping of capillary oscillations on liquid columns

NASA Astrophysics Data System (ADS)

Thiessen, David B.; Wei, Wei; Marston, Philip L.

2002-05-01

Active control of acoustic radiation pressure and of electrostatic stresses on liquid columns has been demonstrated to overcome the Rayleigh-Plateau instability that normally causes long liquid columns to break [M. J. Marr-Lyon et al., J. Fluid Mech. 351, 345 (1997); Phys. Fluids 12, 986-995 (2000)]. Though originally demonstrated for liquid-liquid systems in plateau tanks, the electrostatic method also works on columns in air in reduced gravity [D. B. Thiessen, M. J. Marr-Lyon, and P. L. Marston, ``Active electrostatic stabilization of liquid bridges in low gravity,'' J. Fluid Mech. (in press)]. In new research, the electrostatic stresses are applied in proportion to the velocity of the surface of the column so as to actively dampen capillary oscillations of the surface. The mode amplitude is optically sensed and the rate-of-change is electronically determined. Plateau tank measurements and theory both show that the change in damping rate is proportional to the feedback gain. The results suggest that either active control of electrostatic stresses or of acoustic radiation stresses can be used to suppress the response of interfaces to vibration. [Work supported by NASA.

Electrochemical Glucose Sensors—Developments Using Electrostatic Assembly and Carbon Nanotubes for Biosensor Construction

PubMed Central

Harper, Alice; Anderson, Mark R.

2010-01-01

In 1962, Clark and Lyons proposed incorporating the enzyme glucose oxidase in the construction of an electrochemical sensor for glucose in blood plasma. In their application, Clark and Lyons describe an electrode in which a membrane permeable to glucose traps a small volume of solution containing the enzyme adjacent to a pH electrode, and the presence of glucose is detected by the change in the electrode potential that occurs when glucose reacts with the enzyme in this volume of solution. Although described nearly 50 years ago, this seminal development provides the general structure for constructing electrochemical glucose sensors that is still used today. Despite the maturity of the field, new developments that explore solutions to the fundamental limitations of electrochemical glucose sensors continue to emerge. Here we discuss two developments of the last 15 years; confining the enzyme and a redox mediator to a very thin molecular films at electrode surfaces by electrostatic assembly, and the use of electrodes modified by carbon nanotubes (CNTs) to leverage the electrocatalytic effect of the CNTs to reduce the oxidation overpotential of the electrode reaction or for the direct electron transport to the enzyme. PMID:22163652

Electrochemical glucose sensors--developments using electrostatic assembly and carbon nanotubes for biosensor construction.

PubMed

Harper, Alice; Anderson, Mark R

2010-01-01

In 1962, Clark and Lyons proposed incorporating the enzyme glucose oxidase in the construction of an electrochemical sensor for glucose in blood plasma. In their application, Clark and Lyons describe an electrode in which a membrane permeable to glucose traps a small volume of solution containing the enzyme adjacent to a pH electrode, and the presence of glucose is detected by the change in the electrode potential that occurs when glucose reacts with the enzyme in this volume of solution. Although described nearly 50 years ago, this seminal development provides the general structure for constructing electrochemical glucose sensors that is still used today. Despite the maturity of the field, new developments that explore solutions to the fundamental limitations of electrochemical glucose sensors continue to emerge. Here we discuss two developments of the last 15 years; confining the enzyme and a redox mediator to a very thin molecular films at electrode surfaces by electrostatic assembly, and the use of electrodes modified by carbon nanotubes (CNTs) to leverage the electrocatalytic effect of the CNTs to reduce the oxidation overpotential of the electrode reaction or for the direct electron transport to the enzyme.

Mapping Physical Characteristics of the Columbia River Mouth Using Transmittered Diving Waterbirds

DTIC Science & Technology

2013-09-30

Fisheries and Wildlife Oregon State University 104 Nash Hall Corvallis, OR 97331 Phone: 541-737-1955 Fax: 541-737-3590 Email: daniel.roby...oregonstate.edu Donald E. Lyons Oregon Cooperative Fish and Wildlife Research Unit Department of Fisheries and Wildlife Oregon State University 104...Fish and Wildlife Research Unit Department of Fisheries and Wildlife Oregon State University 104 Nash Hall Corvallis, OR 97331 Phone: 360-510-8904

[Accepting a mastectomy thanks to socio-aesthetics].

PubMed

Arquillière, Agnès; Blanc, Nathalie

2012-12-01

For women of all ages, a mastectomy can affect their body image and femininity. Poor management, both physical and emotional, of a breast removal, can have major consequences on a patient's intimate, family and social life. In the framework of the multi-disciplinary treatment of breast cancer, a team in Lyon carried out a study on the impact of including socio-aesthetic practices in the overall care.

Identification of Components or Fractions Associated with Adverse Changes in Freeze Dried Chicken and Pork during Storage

DTIC Science & Technology

1978-06-01

Products Util- ization and Marketing Research Laboratory, Richard B. Russcll Agricultural Research Center, Agricultural Research Service, United States...was to determine the effect of the salt phosphate treatment on rehydration. Dr. Arthur J. Mercuri, Chief, Animal Products Utilization and Marketing ... Research Laboratory served as Project Lj.ader, with Fir. A. A. Klose and Dr. W. E. Townsend, Frincipal investigators, and Ms. Brenda Lyon, Technician

[The decoration of Italian Renaissance drug jars after engravings].

PubMed

Drey, R E

1994-01-01

Although Italian drug jar painters generally devised original compositions for the ornamentation of their products, on occasion they derived their subjects from printed sources. Printed sources used by drug jar artists of the Renaissance include wood-engraved Italian tarot cards and wood-engraved illustrations by Hans Sebald Beham and Bernard Salomon in miniature bibles published in the sixteenth century in Frankfurt and in Lyons respectively.

Mechanisms for Human Spatial Competence

DTIC Science & Technology

2007-01-01

Published as Lecture Note: Gunzelmann, G., & Lyon, D. R. (2007). Mechanisms of human spatial competence. In M . K. T. Barkowsky, G. Ligozat, & D...the ACT-R community. References 1. Richardson, A., Montello, D., Hegarty, M .: Spatial Knowledge Acquisition from Maps, and from Navigation in Real...Rotation of Three-Dimensional Objects. Science 171, 701–703 (1971) 7. Just, M ., Carpenter, P.: Cognitive Coordinate Systems: Accounts of Mental

An Analysis of Factors Influencing the Turnover of United States Air Force Pilots in the Six to Eleven Year Group

DTIC Science & Technology

1980-06-01

1979. 16. Donnelly, James H., Jr., James L. Gibson, and JohnM. Ivancevich . Organizations--Structure, Processes, Behavior. Dallas TX: Business...Publications, Inc., 1973. 17. Ivancevich , John M., Andrew D. Szilagyi, Jr., and Marc J. Wallace, Jr. Organizational Behavior and Performance. Santa Monica CA...215. 102 Lyons , Colonel Billy S., USAF, and Colonel KZjnald L. Marks, USAF. "An Alternate Pilot Management Pro- gram for Future Strategic Weapon

A Review of Potential Moderating Factors in the Stress-Performance Relationship

DTIC Science & Technology

1992-06-01

accuracy in small groups. Organizational Behavior and Human Performance, 27, 119-134. Ivancevich , J. M. & Donnelly, J. H. (1975). Relation of organizational...structure to job satisfaction, anxiety- stress, and performance. Administrative Science Quarterly, 20, 272-280. Ivancevich , J. M. & Matteson, M. T...of Personality and Social Psychology, L7, 378-389. Lyons , T. F. (1971). Role clarity, need for clarity, satisfaction, tension, and withdrawal

The Shock and Vibration Digest. Volume 14, Number 8

DTIC Science & Technology

1982-08-01

generating interest in averaged transfer functions. Broadband transfer functions are derived using the methods of statistical energy analysis (SEA...Accelerometer, Endevco Corp., San Juan Capis- trano,CA(1982). 7. Lyon, R.H., Statistical Energy Analysis of Dy- namical Systems, MIT Press, Cambridge, MA...A fairly new technique known as statistical energy analysis , or SEA, [35-44] has been useful for many problems of noise transmission. The difficulty

[Claude Balme, a caregiver of the Egyptian expedition of Bonaparte (1766-1850)].

PubMed

Ségal, Alain

2014-01-01

The author explains military surgeon Balme's biograpyhy, especially during Bonaparte's Egyptian campaign (1798-1801). As there is some possible confusion with another Claude Balme, some archives deserve to be closely scrutinized. Through Balme's reports the author insists on his courageous part in several scurvy or plague epidemics. He was himself marked on his face; he ended his life in Lyons as a town-councillor.

Upstream Passage, Spawning, and Stock Identification of Fall Chinook in the Snake River, 1992 and 1993 : Final Report.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Blankenship, H. Lee; Mendel, Glen W.

This final report of the 3-year study summarizes activities and results for 1993. Study objectives were to: (1) determine the source of losses (or accounting errors) for adult chinook salmon between Ice Harbor Dam (IHR) and Lower Granite Dam (LGR), and upstream of LGR in the Snake River; (2) identify spawning locations upstream of LGR for calibration of aerial redd surveys, redd habitat mapping, carcass recovery for genetic stock profile analysis, and correction of estimated adult/redd ratios; and (3) estimate passage and migration times at Snake River. 200 fall chinook salmon were radio tagged and tracked with aerial, fixed-site, andmore » ground mobile tracking. Fish were released upstream of IHR at Charbonneau Park (CHAR). 190 of the fish were tracked or relocated away from CHAR. 59 fish descended to below IHR without crossing Lower Monumental Dam (LMO). Another 128 salmon passed upstream of LMO without falling back at IHR. Only 80 salmon passed Little Goose Dam (LGO) without falling back at a downstream dam; 66 of these fish passed LGR. Many fish that fell back reascended the dams. A total of 72 salmon released at CHAR passed upstream of LGR, including fish that had fallen back and reascended a dam. Over 80 percent of the salmon that entered Lyons Ferry Hatchery each year had reached LGO before descending to the hatchery. Extensive wandering was documented between LMO and upstream of LGR before salmon entered Lyons Ferry Hatchery or the Tucannon River. In 1993, 41 salmon were found to be of hatchery origin when recovered. These fish entered Lyons Ferry Hatchery with similar movements to unmarked salmon. Each year a few salmon have remained near the hatchery without entering, which suggests the hatchery may have inadequate attraction flows. Fall chinook passed lower Snake River dams in 2-5 days each on average. Median travel times through LMO and LGO were 1.0-1.3 days each, which was slower than for spring chinook or steelhead in 1993. 5 refs., 21 figs., 20

[Defusing of victims of the terrorist attacks in Paris. Elements of assessment one-month post-event].

PubMed

Prieto, N; Cheucle, E; Faure, P; Digard, F; Dalphin, C; Pachiaudi, V; Simond, M; Darbon, R; Collinet, C; Habibi, R; Gueugniaud, P-Y

2018-04-01

The terrorist attacks (fusillades and suicide attacks) in Paris on 13 November 2015 have had a major psychic impact on all individuals directly or secondarily exposed to them. Medico-psychological unit (CUMP) of the Paris Île-de-France region's immediate care services were immediately mobilized and rapidly strengthened by all regional medico-psychological units (CUMP) throughout the country. Psychological assistance has been provided in several key points of Paris and specifically in the 11th district City Hall of Paris where Lyon's Medico-psychological unit was located. These specific immediate psychological assistances, referred to as a "defusing process" by the medico-psychological unit (CUMP), are mostly devoted to provide the victims with an entry point to a psychological healthcare relationship and give them a first sense of soothing and relief even though they do not prevent further psychological care follow up for the victims. Nonetheless, the potential therapeutic effect of this "defusing process" has not yet been sufficiently established nor demonstrated by any scientific study. A phoning survey was carried out one-month post-terrorist attacks and interviewed the 129 victims who benefited from the "defusing process" conducted by Lyon's medico-psychological unit (CUMP) in order to collect data and assess its effects. These people, whether directly exposed, bereaved relatives or witnesses, whose average age is 35, are mostly living in the Île-de-France region. Most of them present a high score on the IES-R scale, whether they were directly exposed, bereaved relatives or witnesses. Almost all of them (96.5%) experienced at least one medical care contact within this one-month post-trauma period with psychotropic medication for 37% of them. Regarding the defusing conducted by Lyon's medico-psychological unit (CUMP) in the 11th district City Hall of Paris, it appears that 93% of the victims who were looked after indicated that they were satisfied and 87.4% of

Isolation of Estrogen Regulated Genes from MCF-7 Human Mammary Cancer Cells

DTIC Science & Technology

1990-07-13

Syrian hamster BHK cells. The expression of approximately five hundred clones increased at various points in Gl transit (Hirschhom er d., 1984). No...hyperplasia of ductal epithelium of the mammary gland (Lyons etal., 1958). Biochemical changes in uterine wet weight, protein content, and nucleic... transition from a resting to a growing state (Kaufman and Sharp, 1983). Similarly post- transcriptional processing appears to be important in the ceU

Development of Sub-Ischial Prosthetic Sockets with Vacuum-Assisted Suspension for Highly Active Persons with Transfemoral Amputations

DTIC Science & Technology

2011-10-01

International Conference on Robotics and Automation, Pasadena CA, USA, May 19-23, 2008, p 3672-3677. APPENDICES A Socket Breakdown for Scanning...the LimbLogic is the more efficient of the two pumps. These tests also showed that the performance for both pumps was self -consistent over the...Donelan, J. M. Biomechanical Energy Harvesting: Apparatus and Method. IEEE International Conference on Robotics and Automation, May 19-23, 2008. Lyon

A Study of Bird Ingestions Into Large High Bypass Ratio Turbine Aircraft Engines.

DTIC Science & Technology

1984-09-01

Amrican Sparrovhawk (Kestral) 4 -- 2 5K26 Falco cherrug - Saker Falcon 36 (26-46) 1 5K54 GALLIFORNES - CHICKEN -LIKE BIRDS PHASIANIOAE - QUAILS, PHEASANTS...Palmas, Canary Is. LUX Luxembourg, Luxembourg LYS Lyon, France NAA Madras, India MAD Madrid, Spain MEL Melbourne, Australia MEX Mexico City, Mexico ...Minnesota, USA MSY New Orleans, Louisiana, USA MTY Monterrey, Mexico MYO Montevideo, Uruguay MWH Moses Lake, Washington, USA MXP Milan, Italy - Malpensa

Guidelines for Integrating Helicopter Assets into Emergency Planning

DTIC Science & Technology

1991-07-01

maximum. 35 TABLE 2 HELIPORT INFORMATION SOURCES Professional-and/or industry associations Airborne Law Enforcement Association ( ALEA ) 8060 Balboa Boulevard...Department of Transportation/ Federal Aviation Adminisration ATTN: Hugh Lyon (ASW-611C) Fort Worth, TX 76193-0611 81-624-5600 FAA Northwest Mountain ...indication of wind speed and direction. in areas with swirling or varying winds, such as near buildings or in mountainous areas, two or more wind

Electrochemical Behavior of the Oxide Formed by Reduction of RuO4(2-): A ph-Dependent Ruthenium Oxide-Based Microelectrochemical Transistor

DTIC Science & Technology

1990-05-16

Angerstein-Kozlowska, H.; Vukovic , M.; Conway, B. E. J . Electrochem. Soc. 1978, 125, 1473. 15. Earke, L. D.; Mulcahy, J . K.; Venkatesan, S. J ...90 5f / . j . CON 16. SUPPLEMENTARY NOTATION Prepared for publication in Chemistry of Materials 17. COSATI CODES 18. SUBJECT ;ERMS (Continue on reverse...Microelectrochemical Transistor by Donald F. Lyons, Martin 0. Schloh, James J . Hickman and Mark S. Wrighton Prepared for Publication in Chemistry of Materials

[Disability, for a revolution of thought and action].

PubMed

Gardou, Charles

2014-05-01

While considerable progress has been made, disabled people are still perceived as "separate" beings in our society. For them to be integrated, it is necessary to accept their difference and favour their autonomy. The respect of the rights of disabled people thereby enables professionals to position themselves within an ethical support approach. An interview with Charles Gardou, an anthropologist and university professor at Lumière-Lyon 2 University.

Auditory Models for Speech Analysis

DTIC Science & Technology

1988-01-01

to encode stimulus frequency by firing in period with the clicks, up to a critical value. (Godfrey ct al., 1975). Some binaural processing appears to...masking experiments avoid sinosoiVs since a sinusoidal signal combined with a sinusoidal masker can cause " beats " due to regular fluctuations in the...such as sound localisation (Lyon, 1983). Jeffress (1956) proposed a binaural localisation model where the "mechanism receives impulses from corresponding

Survey of Commercial Small Lithium Polymer Batteries

DTIC Science & Technology

2007-09-19

by a liquid electrolyte which is made conductive for Li ions by the addition of a salt such as lithium hexafluorophosphate (LiPF6). The...Naval Research Laboratory Washington, DC 20375-5320 NRL/MR/6110--07-9073 Survey of Commercial Small Lithium Polymer Batteries September 19, 2007... Lithium Polymer Batteries Arnold M. Stux and Karen Swider-Lyons Naval Research Laboratory 4555 Overlook Avenue, SW Washington, DC 20375-5320 NRL/MR

Remedial Investigation Report Cold Regions Research and Engineering Laboratory, Hanover, New Hampshire

DTIC Science & Technology

1992-10-01

older) Wisconsin glacial advance, known in Vermont as the Bennington Glacial Stade, glaciers advanced primarily from the northwest. A glacier lake formed...Internal Report 1088, Hanover, New Hampshire. Hadley, J.B., 1950, Geology of the Bradford-Thetford area, Orange County, Vermont , Bulletin No. 1, Vermont ...CRREL Section No.: 10 Revision No.: 2 Date: October 1992 Lyons, J.B. 1955, Geology of the Hanover Quadrangle, New Hampshire - Vermont , Geological

Reflections on Over Fifty Years in Research and Development; Some Lessons Learned

DTIC Science & Technology

2012-02-01

his career in chemical research and development at the Monsanto Chemical Company. Dr. Lyons received his AB in chemistry from Harvard College and...developing new uses for its products (applications research). Chemical Applications in the Field My first task at the Monsanto Research Laboratory was...permanent employees, post-doctoral fellows, and guest workers. When I was at Monsanto Company, a special class of “stars” was singled out by management

Regulatory Fit and Equal Opportunity/Diversity: Implications for DEOMI

DTIC Science & Technology

2013-01-01

than demographic diversity ( Ivancevich & Gilbert, 2000); the goal of equality is to create and manage a heterogeneous mix of abilities, skills, ideas...accepted. Recruiting of minorities and women are not seen as violations of EO laws (Kravitz, 2008; Newman & Lyon , 2009; Pyburn, et al., 2008). Similarly...209-213. REGULATORY FIT AND EQUAL OPPORTUNITY/DIVERSITY 23 Ivancevich , J. M. & Gilbert, J. A. (2000). Diversity management: Time for a new approach

Regulatory Fit and Equal Opportunity/Diversity: Implications for the Defense Equal Opportunity Management Institute (DEOMI)

DTIC Science & Technology

2013-01-01

than demographic diversity ( Ivancevich & Gilbert, 2000); the goal of equality is to create and manage a heterogeneous mix of abilities, skills, ideas...accepted. Recruiting of minorities and women are not seen as violations of EO laws (Kravitz, 2008; Newman & Lyon , 2009; Pyburn, et al., 2008). Similarly...209-213. REGULATORY FIT AND EQUAL OPPORTUNITY/DIVERSITY 23 Ivancevich , J. M. & Gilbert, J. A. (2000). Diversity management: Time for a new approach

Small, Short Duration Technical Team Dynamics

DTIC Science & Technology

2006-05-01

Organizations and a Strategy of Implementation. Academy of Management Journal. Vol. October, pp. 98-111. Ivancevich , John M. 1974. A Study of a Cognitive...Training Program: Trainer Styles and Group Development. Academy of Management Journal. Vol. 17, No. 3, p. 428. 315 Ivancevich , John M. and J...Vol. 90, pp. 141-153. Lyon , J. Michael. 2003. Mentoring of Scientists and Engineers: Dyadic and Formality Effects on Career Development and

The Ogaden Insurrection: Implications for Islamist Extremism and U.S. National Security

DTIC Science & Technology

2011-02-16

DISTRIBUTION A. Approved for public release: distribution unlimited i DISCLAIMER The views expressed in this academic research paper are those of...23 Terrence Lyons, “Avoiding Conflict in the Horn of Africa, U.S. Policy Toward Ethiopia and Eritrea,” Council on Foreign Relations, CSR No. 21...ballot box and [the EPRDF regards] the expression of differing views and interests as a form of betrayal,” and are therefore repressed. International

Apparatus and Methods Using Highly Optically Dispersive Media

DTIC Science & Technology

2011-08-02

University ; Sep. 24, 2001. * cited by examiner Primary Examiner- Michael A Lyons (74) Attorney , Agent, or Firm- William J. Greener; Bond...NY (US); Daniel J. Gauthier, Durham, NC (US); Zhimin Shi, Rochester, NY (US) (73) Assignees: University of Rochester, Rochester, NY (US); Duke... University , Durham, NC (US) ( *) Notice: Subject to any disclaimer, the term of this patent is extended or adjusted under 35 U.S.C. 154(b) by 250

Flame Propagation and Blowout in Hydrocarbon Jets: Experiments to Understand the Stability and Structure

DTIC Science & Technology

2012-07-29

Wilson and Kevin M. Lyons. On Diluted-Fuel Combustion Issues in Burning Biogas Surrogates, ASME-JERT, (12 2009): . doi: 2010/01/07 10:47:38 2 TOTAL...four coflow velocities are used, resulting in eight additional flow configurations. Table 2 contains the data obtained for these configurations, as...counterflow have higher stability limits than those in an oblique configuration. 4.) Conclusions Based on the results obtained from this experiment, a

Optimal Regulation of Structural Systems with Uncertain Parameters.

DTIC Science & Technology

1981-02-02

been addressed, in part, by Statistical Energy Analysis . Moti- vated by a concern with high frequency vibration and acoustical- structural...Parameter Systems," AFOSR-TR-79-0753 (May, 1979). 25. R. H. Lyon, Statistical Energy Analysis of Dynamical Systems: Theory and Applications, (M.I.T...Press, Cambridge, Mass., 1975). 26. E. E. Ungar, " Statistical Energy Analysis of Vibrating Systems," Trans. ASME, J. Eng. Ind. 89, 626 (1967). 139 27

A Mechanical Power Flow Capability for the Finite Element Code NASTRAN

DTIC Science & Technology

1989-07-01

perimental methods. statistical energy analysis , the finite element method, and a finite element analog-,y using heat conduction equations. Experimental...weights and inertias of the transducers attached to an experimental structure may produce accuracy problems. Statistical energy analysis (SEA) is a...405-422 (1987). 8. Lyon, R.L., Statistical Energy Analysis of Dynamical Sistems, The M.I.T. Press, (1975). 9. Mickol, J.D., and R.J. Bernhard, "An

Prediction of external corrosion for steel cylinders at the Paducah Gaseous Diffusion Plant: Application of an empirical method

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lyon, B.F.

1996-02-01

During the summer of 1995, ultrasonic wall thickness data were collected for 100 steel cylinders containing depleted uranium (DU) hexafluoride located at Paducah Gaseous Diffusion Plant (PGDP) in Paducah, Kentucky. The cylinders were selected for measurement to assess the condition of the more vulnerable portion of the cylinder inventory at PGDP. The purpose of this report is to apply the method used in Lyon to estimate the effects of corrosion for larger unsampled populations as a function of time. The scope of this report is limited and is not intended to represent the final analyses of available data. Future effortsmore » will include continuing analyses of available data to investigate defensible deviations from the conservative assumptions made to date. For each cylinder population considered, two basic types of analyses were conducted: (1) estimates were made of the number of cylinders as a function of time that will have a minimum wall thickness of either 0 mils (1 mil = 0.00 1 in.) or 250 mils and (2) the current minimum wall thickness distributions across cylinders were estimated for each cylinder population considered. Additional analyses were also performed investigating comparisons of the results for F and G yards with the results presented in Lyon (1995).« less

Screening of young competitive athletes for the prevention of sudden cardiac death with a wireless electrocardiographic transmission device: a pilot study.

PubMed

Cho, Jae Hyung; Selen, Mats A; Kocheril, Abraham G

2015-08-11

The 12-lead electrocardiographic screening for the prevention of sudden cardiac death in young competitive athletes is not cost-effective and thus not routinely recommended. We investigate whether a less expensive wireless electrocardiographic transmission device can be used to screen for the prevention of sudden cardiac death in this population. During pre-participation screening, twenty college football players underwent two electrocardiograms: a conventional 12-lead electrocardiogram and a wireless 9-lead electrocardiogram. We compared several electrocardiographic parameters (QRS duration, left ventricular hypertrophy using the Cornell voltage criteria and the Sokolow-Lyon criteria, ST deviation and corrected QT interval) to determine the correlation. The QRS duration, left ventricular hypertrophy using the Cornell voltage criteria and the Sokolow-Lyon criteria and corrected QT interval exhibited significant correlation between the two types of electrocardiograms (correlation coefficient 0.878, 0.630, 0.770 and 0.847, respectively with P values of 0.01, 0.003, 0.01 and 0.01, respectively). ST deviation in V1 was weakly correlated between the two types of electrocardiograms without statistical significance (correlation coefficient 0.360 with a P value of 0.119). Our newly developed wireless 9-lead electrocardiogram demonstrated significant correlations with a conventional 12-lead electrocardiogram in terms of QRS duration, left ventricular hypertrophy and corrected QT interval.

Structural aspects of the inactive X chromosome.

PubMed

Bonora, Giancarlo; Disteche, Christine M

2017-11-05

A striking difference between male and female nuclei was recognized early on by the presence of a condensed chromatin body only in female cells. Mary Lyon proposed that X inactivation or silencing of one X chromosome at random in females caused this structural difference. Subsequent studies have shown that the inactive X chromosome (Xi) does indeed have a very distinctive structure compared to its active counterpart and all autosomes in female mammals. In this review, we will recap the discovery of this fascinating biological phenomenon and seminal studies in the field. We will summarize imaging studies using traditional microscopy and super-resolution technology, which revealed uneven compaction of the Xi. We will then discuss recent findings based on high-throughput sequencing techniques, which uncovered the distinct three-dimensional bipartite configuration of the Xi and the role of specific long non-coding RNAs in eliciting and maintaining this structure. The relative position of specific genomic elements, including genes that escape X inactivation, repeat elements and chromatin features, will be reviewed. Finally, we will discuss the position of the Xi, either near the nuclear periphery or the nucleolus, and the elements implicated in this positioning.This article is part of the themed issue 'X-chromosome inactivation: a tribute to Mary Lyon'. © 2017 The Authors.

Forecasting Air Force Logistics Command Second Destination Transportation: An Application of Multiple Regression Analysis and Neural Networks

DTIC Science & Technology

1990-09-01

without the help from the DSXR staff. William Lyons, Charles Ramsey , and Martin Meeks went above and beyond to help complete this research. Special...develop a valid forecasting model that is significantly more accurate than the one presently used by DSXR and suggested the development and testing of a...method, Strom tested DSXR’s iterative linear regression forecasting technique by examining P1 in the simple regression equation to determine whether

Computer-Based Instruction Authoring Tools System (CATS): Lesson Maintenance

DTIC Science & Technology

1990-07-01

Tols-System ( CATS ): Lesson Maintenance Vol N. Hutton Michael R. Flaningam Barbara Tarker Ann Rybowlak Susan Sulzbach Mark Lyon Brian Thomason DTC"",~1...Authoring Tools &ystem ( CATS ): Lesson Maintenance Vel N. Hulton Michael R. Flaningam Barbara Tarker Ann Rybowiak Navy Personnel Research and...lools •ystem ( CATS ): Program Element 0604722A Lesson Maintenance 6. AUTHOR(S) V. N. Huhoa, N. R. Fl1ingam. B. Tarktr, A. Rybowiak. S. Sulzbach. M

Three-Dimensional Cloud Visualization Based on Satellite Imagery

DTIC Science & Technology

1992-12-01

that information. As assessed by Schiavone and Papathomas (1990), a major challenge in meteorology today is the need to optimize the human/computer...program used on SGI system. Author: Eric Pepke, Jim Murray, John Lyons, August 1992, Florida State University. 58 S...Oceanography, and Hydrology. Amer. Meteor. Soc., Boston, MA, pp. 93-99 60 • • • • •• ,••’ "O Schiavone , J. A., and T. V. Papathomas, 1990

Public Affairs: Inform, Educate, and Influence

DTIC Science & Technology

2009-06-12

directed towards domestic target audiences. Outside of the military and scholarly material, there is a large amount of news and opinion articles, books ...program, which began in earnest during Operation Iraqi Freedom in 2003, has been discussed in great lengths in scores of books , studies and editorials...few examples of books about the DOD‘s embed program follows: Embedded: The Media at War in Iraq by Bill Katovsky and Timothy Carlson - Lyons Press

Structuring as an Aid to Performance in Base-Rate Problems.

DTIC Science & Technology

1988-06-01

Design. All subjects were given two base-rate problems, here called the Lightbulb problem (adapted from Lyon & Slovic, 1976) and the Dyslexia problem; both...are shown in Table 1. Approximately half the subjects received the Lightbulb problem first; the others received the Dyslexia problem first. The two...probability that this bulb is really defective? [the child really has dyslexia ]? You can probably give a good estimate if you think hard and carefully

A Methodology for Assessing the Military Benefits of Science and Technology Investments

DTIC Science & Technology

2008-09-01

and sources for this paper were drawn from unclassified materials. Albert Sciarretta is a Senior Research Fellow at the Center for Technology and...should be noted that Dr. Killion also co-authored the unpublished paper , “Measuring Return on investment for Army Basic Research ,” provided as appendix C...Lyons, “Army R&D Collaboration and The Role of Globalization In Research ,” Defense & Technology Paper 51 (Washington, DC: Center For Technology and

Historical Report Atomic Bomb Tests Able and Baker (Operation Crossroads). Volume 2

DTIC Science & Technology

1946-07-25

was obvious that the Bur- eau of Medicine and Surgery representative to the Task Force, Capt. G. M. Lyon (MC), must be responsible not only for the...Reboarding and Inspection Plan of the operation by detailed planning of its own activities. 1 See Annex X, App. Ill: Bureau of Medicine and Surgery...substitute for personnel, with the expectation that the use of these animals would reveal in- formation applicable to the protection and treatment

Measurements and Analysis of Reverberation and Clutter Data

DTIC Science & Technology

2007-04-01

triplet arrays and the DRDC ar- ray with combined omnidirectional and dipole sensors. A fast shallow water reverberation model was extended to...Bistatic reverberation models are too slow for inversion, but model-data comparisons will be made using ray -based models, e.g. GSM [11], or normal-mode...July 2000, pp. 1183–1188, European Commission, Luxembourg. Meeting held at Lyon, France. [36] Weinberg, H. and Keenan, R. E. (1996), Gaussian ray

Histone Methylation and Epigenetic Silencing in Breast Cancer

DTIC Science & Technology

2008-07-01

Curr Opin Genet Dev 14(2): 155-164. Caretti, G ., Di Padova, M., Micales, B., Lyons, G.E., and Sartorelli, V. 2004. The Polycomb Ezh2...tissues. Cancer Res 66(8): 4095-4099. Egger, G ., Liang, G ., Aparicio, A., and Jones, P.A. 2004. Epigenetics in human disease and prospects for...Widschwendter, M., Fiegl, H., Egle, D., Mueller-Holzner, E., Spizzo, G ., Marth, C., Weisenberger, D.J., Campan, M., Young, J., Jacobs, I., and Laird

Selfless Service: The Cavalry Career of Brigadier General Samuel M. Whitside from 1858 to 1902

DTIC Science & Technology

2002-05-31

and Captain Richard C. Lay inspected and mustered the whole command at this post [Fort Lyons, Colorado ] this afternoon. It was interesting to see him...and the Whitsides spent several months in Colorado Springs, Arkansas, then traveled to her hometown of Nashville, Tennessee, and finally to his...location. The Whitsides spent little time at Fort Apache before B and F Troops received orders to relocate to Fort Lewis, Colorado , which was in the

Innovative Technologies for Maskless Lithography and Non-Conventional Patterning

DTIC Science & Technology

2008-08-01

wave sources are used and quantitative data is produced on the local field intensities and scattered plane and plasmon wave amplitudes and phases...transistors”, Transducers 2007, Lyon, France, 3EH5.P, 2007. 9. D. Huang and V. Subramanian “Iodine-doped pentacene schottky diodes for high-frequency RFID...wave sources are used and quantitative data is produced on the local field intensities and scattered plane and plasmon wave amplitudes and phases

Composition and Photochemical Reactivity of Turbine Engine Exhaust

DTIC Science & Technology

1984-09-01

ESL-TR-84-28 Composition and Photochemical Reactivity of Turbine Engine Exhaust In IL) C.W. SPICER. M.W. HOLDREN, T.F. LYON. and R.M. RIGGIN...NUMBER 2. GOVT ACCIESION NO RECIPIENT’S CATALOG NUMmE" 4. TITLE (aid Sub•ttlC) S. TYPE OF REPORT & PERIOD COvERE0 Composition and Photochemical...involved detailed exhaust organic composition studies with two -. full-scale turbine engines utilizing three fuels. Tiask 4 investigated the

Procedural Semantics as a Theory of Meaning.

DTIC Science & Technology

1981-03-01

Aaron Sloman (none of whom can be held responsible, of course, fcor the opinions expressed herein). Special thanks are also due to John Lyons for valuable...Meanings 12 7 Parametric Ambiguity 14 8 The Economic Necessity of Ambiguity 16 9 Semantic Interpretation 19 10 Semantics of the Internal Language 21 11...sufficiently low order organisms, the behavioral characteristics of that organism in response to stimuli are essentially "wired in" by their genes

Proceedings of the NASTRAN (Tradename) Users’ Colloquium (17th) Held in San Antonio, Texas on 24-28 April 1989

DTIC Science & Technology

1989-03-01

statistical energy analysis , the finite clement method, and the power flow method. Experimental solutions are the most common in the literature. The authors of...to the added weights and inertias of the transducers attached to an experimental structure. Statistical energy analysis (SEA) is a computational method...Analysis and Diagnosis," Journal of Sound and Vibration, Vol. 115, No. 3, pp. 405-422 (1987). 8. Lyon, R.L., Statistical Energy Analysis of Dynamical Systems

The Shock and Vibration Digest. Volume 13, Number 12

DTIC Science & Technology

1981-12-01

Resulting Unsteady Forces and Flow Phenomenon. Part III 26 BOOK REVIEWS STATISTICAL ENERGY ANALYSIS Chapter IV considers the problems of estimating J OF...stress, acceleration, modes. Statistical energy analysis (SEA), which is and pressure; estimations of the average system expressed in terms of random...by F.C. Nelson, SVD, 13 (8), pp 30-31 (Aug 1981) Lyons, R.H., Statistical Energy Analysis of Dynamic Systems, MIT Press, Cambridge, MA; Revieed by H

Westernization or Modernization: The Political, Economic and Social Attitudes and Desires of the Post-Khomeini Generation in Iran

DTIC Science & Technology

2006-05-25

banned, things as simple as meeting in public with members of the opposite sex , listening to pop music, and holding hands in public became acts of...treatment of this topic see Reading Lolita In Iran: A Memoir In Books, by Azar Nafisi, or Geneive Abdo and Jonathan Lyons work, Answering Only To God...contact with members of the opposite sex . In return for these freedoms, there would be an implicit agreement to give up the call for political

Cultural Resources Literature Search and Records Review of the Upper Minnesota River Subbasin, Southwestern Minnesota and Northeastern South Dakota. Volume 1.

DTIC Science & Technology

1980-05-01

CORPS OF ENGERS 1135 U.S. Post Office and Custan House St. Paul, Mirffesota, 55101 Contract No. DACW7-79-C-019 9 LAC #Ift P-l L E ~ &-W N L & - Prepared...By: ARCHAEODLOGICAL FIELD SERVICES, INC. 4?? SOUTTI YAIN STPCET SUIT~ E 4?? 5, STILLWATER MINNESOTA 55082 * .- ~. % ,..VOLE I CULTURAL RESOURCES...County, Minnesota 4. Re&ood County, Minnesota E . Cottonwood River Subbasin 261 1. Brown County, Minnesota 2. Cottorwod County, Minnesota 3. Lyon County

Liquid Hydrogen Fuel System for Small Unmanned Air Vehicles

DTIC Science & Technology

2013-01-07

the Office of Naval Research for support of this research. VII. References 1 R. Stroman, J.C. Kellogg, K. Swider-Lyons, “Testing of a PEM Fuel Cell ...energy storage system. The Naval Research Laboratory has been extending the duration of electric UAVs through the use of hydrogen fuel cells , which...take advantage of both the high energy of H2 fuel in combination with the high efficiency (~50%) of polymer fuel cells . In this paper, we describe

International Conference on Thermoelectrics(16th), Proceedings, ICT 󈨥 Held in Dresden, Germany on August 26-29, 1997

DTIC Science & Technology

1998-05-08

mixed valence state, i.e., Ru2+ and Ru4+. Such valence fluctuations were recently confirmed by x - ray absorption near-edge structure analysis [44... Kanatzidis , H. B. Lyon, Jr., and G. Mahan, page 55, Materials Research Society Press, Pittsburgh, PA, 1997. 23 T. Koga, S. B. Cronin, T. C. Harman, X ...are generally for detectors of all sorts: infra-red, X ray , gamma ray etc. because lowering the temperature reduces the noise and increases the

Geobiology of Marine Magnetotactic Bacteria

DTIC Science & Technology

2006-06-01

acids (e.g. lactate, acetate, oxalate , succinate, fumarate, malate, and citrate) which are continually transported into the soil, in part due to the...microbial mats, and hydrothermal vent waters. J Environ Monit 3: 61-66. 177 Lyons TW (1997) Sulfur isotopic trends and pathways of iron sulfide formation in...case in sediments, microbial mats, and hydrothermal vent waters. J Environ Monit 3: 61-66. 200 O’Sullivan DW, Hanson Jr AK, Kester DR (1997) The

A Survey of Probabilistic Methods for Dynamical Systems with Uncertain Parameters.

DTIC Science & Technology

1986-05-01

J., "An Approach to the Theoretical Background of Statistical Energy Analysis Applied to Structural Vibration," Journ. Acoust. Soc. Amer., Vol. 69...1973, Sect. 8.3. 80. Lyon, R.H., " Statistical Energy Analysis of Dynamical Systems," M.I.T. Press, 1975. e) Late References added in Proofreading !! 81...Dowell, E.H., and Kubota, Y., "Asymptotic Modal Analysis and ’~ y C-" -165- Statistical Energy Analysis of Dynamical Systems," Journ. Appi. - Mech

On the Relationship between Energy Density and Net Power (Intensity) in Coupled One-Dimensional Dynamic Systems

DTIC Science & Technology

1990-03-01

equation of the statistical energy analysis (SEA) using the procedure indicated in equation (13) [8, 9]. Similarly, one may state the quantities (. (X-)) and...CONGRESS ON ACOUSTICS, July 24-31 1986, Toronto, Canada, Paper D6-1. 5. CUSCHIERI, J.M., Power flow as a compliment to statistical energy analysis and...34Random response of identical one-dimensional subsystems", Journal of Sound and Vibration, 1980, Vol. 70, p. 343-353. 8. LYON, R.H., Statistical Energy Analysis of

Uncooled Cantilever Microbolometer Focal Plane Arrays with mK Temperature Resolution: Engineering Mechanics for the Next Generation

DTIC Science & Technology

2009-11-25

34Nanoindentation Stress-Strain Curves of Plasma Enhanced Chemical Vapor Deposited Silicon Oxide Thin Films," Thin Solid Films, 516 (8) (2008) 1941-1951. 9. S...1604. 5. Z. Cao* and X. Zhang, "Measurement of Stress-Strain Curves of PECVD Silicon Oxide Thin Films by Means of Nanoindentation," in Processing...Microsystems (Transducers 󈧋), Lyon, France, June 10-14, 2007. 9. Z. Cao* and X. Zhang, “Measurement of Stress-strain Curves of PECVD Silicon Oxide

Genetic characterization of naturally spawned Snake River fall-run Chinook salmon

USGS Publications Warehouse

Marshall, A.R.; Blankenship, H.L.; Connor, W.P.

1999-01-01

We sampled juvenile Snake River chinook salmon Oncorhynchus tshawytscha to genetically characterize the endangered Snake River fall-run population. Juveniles from fall and spring–summer lineages coexisted in our sampling areas but were differentiated by large allozyme allele frequency differences. We sorted juveniles by multilocus genotypes into putative fall and spring lineage subsamples and determined lineage composition using maximum likelihood estimation methods. Paired sMEP-1* and PGK-2* genotypes—encoding malic enzyme (NADP+) and phosphoglycerate kinase, respectively—were very effective for sorting juveniles by lineage, and subsamples estimated to be 100% fall lineage were obtained in four annual samples. We examined genetic relationships of these fall lineage juveniles with adjacent populations from the Columbia River and from Lyons Ferry Hatchery, which was established to perpetuate the Snake River fall-run population. Our samples of naturally produced Snake River fall lineage juveniles were most closely aligned with Lyons Ferry Hatchery samples. Although fall-run strays of Columbia River hatchery origin found on spawning grounds threaten the genetic integrity of the Snake River population, juvenile samples (a) showed distinctive patterns of allelic diversity, (b) were differentiated from Columbia River populations, and (c) substantiate earlier conclusions that this population is an important genetic resource. This first characterization of naturally produced Snake River fall chinook salmon provides a baseline for monitoring and recovery planning.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Somorjai

The International Symposium on Relations between Homogeneous and Heterogeneous Catalysis (ISHHC) has a long and distinguished history. Since 1974, in Brussels, this event has been held in Lyon, France (1977), Groeningen, The Netherlands (1981); Asilomar, California (1983); Novosibirsk, Russia (1986); Pisa, Italy (1989); Tokyo, Japan (1992); Balatonfuered, Hungary (1995); Southampton, United Kingdom (1999); Lyon, France (2001); Evanston, Illinois (2001) and Florence, Italy (2005). The aim of this international conference in Berkeley is to bring together practitioners in the three fields of catalysis, heterogeneous, homogeneous and enzyme, which utilize mostly nanosize particles. Recent advances in instrumentation, synthesis and reaction studies permitmore » the nanoscale characterization of the catalyst systems, often for the same reaction, under similar experimental conditions. It is hoped that this circumstance will permit the development of correlations of these three different fields of catalysis on the molecular level. To further this goal we aim to uncover and focus on common concepts that emerge from nanoscale studies of structures and dynamics of the three types of catalysts. Another area of focus that will be addressed is the impact on and correlation of nanosciences with catalysis. There is information on the electronic and atomic structures of nanoparticles and their dynamics that should have importance in catalyst design and catalytic activity and selectivity.« less

Left Ventricular Hypertrophy and Cognitive Decline in Old Age.

PubMed

Mahinrad, Simin; Vriend, Annelotte E; Jukema, J Wouter; van Heemst, Diana; Sattar, Naveed; Blauw, Gerard Jan; Macfarlane, Peter W; Clark, Elaine N; de Craen, Anton J M; Sabayan, Behnam

2017-01-01

Patients with advanced heart failure run a greater risk of dementia. Whether early cardiac structural changes also associate with cognitive decline is yet to be determined. We tested whether left ventricular hypertrophy (LVH) derived from electrocardiogram associates with cognitive decline in older subjects at risk of cardiovascular disease. We included 4,233 participants (mean age 75.2 years, 47.8% male) from PROSPER (PROspective Study of Pravastatin in the Elderly at Risk). LVH was assessed from baseline electrocardiograms by measuring the Sokolow-Lyon index. Higher levels of Sokolow-Lyon index indicate higher degrees of LVH. Cognitive domains involving selective attention, processing speed, and immediate and delayed memory were measured at baseline and repeated during a mean follow-up of 3.2 years. At baseline, LVH was not associated with worse cognitive function. During follow-up, participants with higher levels of LVH had a steeper decline in cognitive function including in selective attention (p = 0.009), processing speed (p = 0.010), immediate memory (p < 0.001), and delayed memory (p = 0.002). These associations were independent of cardiovascular risk factors, co-morbidities, and medications. LVH assessed by electrocardiogram associates with steeper decline in cognitive function of older subjects independent of cardiovascular risk factors and co-morbidities. This study provides further evidence on the link between subclinical cardiac structural changes and cognitive decline in older subjects.

Interrelationships of Prenatal and Postnatal Growth, Hormones, Diet, and Breast Cancer

DTIC Science & Technology

2006-03-01

Breslow NE, Day NE. Statistical methods in cancer research, vol. 1. The analysis of case-control studies, IARC Sci. Publ. 32, Lyon, IARC, 1980 . 9...weight (Ekbom et al, 1992; Innes et al, 2000; Michels et al, 1996; Sander- son et al, 1996). Conversely, high adolescent (Coates et al, 1999; Hislop et...Brinton and Swanson, 1992; Choi et al, 1978; Coates et al, 1999; Franceschi et al, 1996; Hislop et al, 1986; Le Marchand et al, 1988a; Pryor et al, 1989

PerSEUS: Ultra-Low-Power High Performance Computing for Plasma Simulations

NASA Astrophysics Data System (ADS)

Doxas, I.; Andreou, A.; Lyon, J.; Angelopoulos, V.; Lu, S.; Pritchett, P. L.

2017-12-01

Peta-op SupErcomputing Unconventional System (PerSEUS) aims to explore the use for High Performance Scientific Computing (HPC) of ultra-low-power mixed signal unconventional computational elements developed by Johns Hopkins University (JHU), and demonstrate that capability on both fluid and particle Plasma codes. We will describe the JHU Mixed-signal Unconventional Supercomputing Elements (MUSE), and report initial results for the Lyon-Fedder-Mobarry (LFM) global magnetospheric MHD code, and a UCLA general purpose relativistic Particle-In-Cell (PIC) code.

Environmental Perturbations, Behavioral Change, and Population Response in a Long-Term Northern Elephant Seal Study

DTIC Science & Technology

2013-09-30

and Physiology a-Molecular & Integrative Physiology 161:388-394. Goldstein, T ., I . Mena, S. J. Anthony, R. Medina, P. W. Robinson, D. J. Greig, D. P...behaviour and foraging success in the northern elephant seal. Functional Ecology 27:1055-1063. Lyons, E. T ., T . A. Kuzmina , T . R. Spraker, N. Jaggi...Klanjšček, T ., Lusseau, D., Kraus, S., McMahon, C.R., Robinson, P. W., Schick, R., Schwarz, L.K., Simmons, S. E., Thomas, L., Tyack, P. and Harwood

Solid State Research

DTIC Science & Technology

1999-02-23

pumped at frequencies up to 5.5 kHz (with 10-W pumping). At high pulse repetition rates the radius of the beam waist decreases to ~60 jum, owing to...1998) A 1.3-GHz SOI CMOS Test Chip for R. Berger Low-Power High -Speed Pulse W. G. Lyons Processing A. M. Soares IEEE J. Solid-State Circuits...Goodhue D. E. Mull J. M. Rossler Y. Royter C.G.Fonstad* /. Vac. Sei. Technol. Modeling the Microwave Impedance of High -Tc Long Josephson

Assessment of Gravel Operation Damage to Prehistoric Sites and Recording the Santa Fe Trail within the John Martin Reservoir Project Area, Bent County, Colorado and Evaluation of Old Las Animas (5BN176), a Late Nineteenth Century Town on the Arkansas River, Bent County, Colorado.

DTIC Science & Technology

1987-06-01

an al ii’nment which orients them towards Fort Lyon. Comparing this to the c’iriul 1 plat for Las Animas City ... ,it can be seen that the streets in...rights, franchises and appurtainances thereunto belonging and, also all that certain piece or parcel of land being and situated within the distance of...rim includes clear, ,irpl, and aqua bottle glass; charcoal; bone; a pontil base olive wine "bttle; and a leather belt part (punched). A heavy growth

A Controlled Trial of Chemoprevention Using COX-2 Inhibitors in an Avian Model of Spontaneous Ovarian Carcinogesis

DTIC Science & Technology

2007-09-01

Lyon J, Liff J, et al. Incidence of ovarian cancer in relation to the use of oral contraceptives . Int J Cancer 1981;28:669-671. 37. Barnes M...Liff J, et al. Incidence of ovarian cancer in relation to the use of oral contraceptives . Int J Cancer 1981;28:669-671. 37. Barnes M, Berry W...of epithelial ovarian cancer. Cancer 1995;76:284-289. 24. Rosenberg L, Palmer J, Zauber A, et al. A case control study of oral contraceptive use and

Colloquium on High Resolution Molecular Spectroscopy (8th), 19-23 September 1983 (Colloque sur la Spectroscopie Moleculaire a Haute Resolution (Huitieme), 19-23 Septembre 1983).

DTIC Science & Technology

1983-09-23

avec lea autres State. A FITTING PROCEDURE FOP EXTENSIVELY PERTURBED HAMILTONIANS APPLICATION TO THE A1I- STATE OF CO ANDRE LE FLOCH AND JEAN MASSON...BENICHOU, Jean -Claude DEROCHE Laboratoire d’Infrarouge, Associg au C.N.R.S. Universitf de Paris-Sud, Bitiment 350 91405 ORSAY Cfdex, France Le pompage...MEUDON, FRANCE and Jean -Yves RONCIN Equipe de Spectroscopie, C.N.R.S. (L.A. 171, Universitis de Lyon I et Saint-Etienne) 158 bis Cours Fauriel, 42023

Ancient Earth, Alien Earths Event

NASA Image and Video Library

2014-08-20

Dr. Timothy Lyons, Professor of Biogeochemistry, UC Riverside, speaks on a panel at the “Ancient Earth, Alien Earths” Event at NASA Headquarters in Washington, DC Wednesday, August 20, 2014. The event was sponsored by NASA, the National Science Foundation (NSF), and the Smithsonian Institution and was moderated by Dr. David H. Grinspoon, Senior Scientist at the Planetary Science Institute. Six scientists discussed how research on early Earth could help guide our search for habitable planets orbiting other stars. Photo Credit: (NASA/Aubrey Gemignani)

Lithium Battery Safety/Cell-to-Cell Failure Project FY14 Progress Report

DTIC Science & Technology

2015-03-06

Delacourt, “Thermal modeling of a cylindrical LiFePO4 /graphite lithium-ion battery.” J. Power Sources 195 (2010) 2961- 2968. 18. T. B. Bandhauer, S...Ren, J. Xie, H. He and F. Xu, “Failure study of commercial LiFePO4 cells in over-discharge conditions using electrochemical impedance spectroscopy...graphite/ LiFePO4 cell.” J. Power Sources 208 (2012) 296-305. 61. N. S. Spinner, C. T. Love, S. G. Tuttle, K. Swider-Lyons and S. L. Rose-Pehrsson

Practical Session: Introduction to R

NASA Astrophysics Data System (ADS)

Clausel, M.; Grégoire, G.

2014-12-01

An introduction to R is proposed. This pratical session is an excerpt from practical exercises proposed by A. Dalalyan at EPNC (see href="http://certis.enpc.fr/~dalalyan/Download/TP_ENPC_1.pdf). Datas are also extracted from a practical session proposed by hydrologic data from Amazonia proposed by D. Chessel A.B. Dufour in Lyon 1 (website indicated in the text below) and from other practical exercises proposed by A. Dalalyan at ENPC (same address as above but ended by /TP_ENPC_4.pdf).

Hypogravity's Effect on the Life Cycle of Japanese Quail

NASA Technical Reports Server (NTRS)

Hester, Patricia Y.

1999-01-01

A series of studies were conducted to determine the effect of activities preceding space-flight and during space-flight on quail embryonic development. While the overall development of the quail embryos was evaluated, the report presented herein, focused on calcium utilization or uptake from eggshells by developing embryos during incubation in space and on earth. In the pre-space trials, fertilized quail eggs were subjected to pre-night dynamics including forces of centrifugation, vibration, or a combination of vibration and centrifugation prior to incubation for 6 or 16 days. In another trial, fertile quail eggs were tested for survivability in a refrigerator stowage kit for eggs (RSKE) which was subsequently used to transport the eggs to space. Eggs in the RSKE were subjected to shuttle launch dynamics including G force and random vibration profiles. In the space- flight trials, 48 fertile quail eggs were launched on space shuttle Flight STS-76 and were subsequently incubated in a Slovakian incubator onboard space station, MIR. Two sets of ground controls each with 48 fertile eggs with and without exposure to launch dynamics were initiated 5 days post-launch. There was a laboratory control (incubated in Lyon RX2 incubator at 37.5 C) and a synchronous control (incubated in Lyon RX2 incubator at 39 - 400 C), which simulated the temperature of the space-flight incubator. Following space-flight trials, post-flight trials were conducted where quail eggs were incubated in Lyon RX2 or Slovakian incubators under various temperatures with or without launch dynamics. Eggshells from all study trials were retrieved and analyzed for calcium content to determine if its utilization by developing quail embryos was affected by activities preceding space-flight or during incubation in space under microgravity. Results from the pre-flight and post-flight showed that pre-flight activities and shuttle launch dynamics had no effect on calcium uptake from the eggshell by developing

Cemex, Inc., Lyons, Colorado; Petition to Object (or reopen) to Title V Operating Permit

EPA Pesticide Factsheets

This document may be of assistance in applying the Title V air operating permit regulations. This document is part of the Title V Petition Database available at www2.epa.gov/title-v-operating-permits/title-v-petition-database.

Expert System for Test Program Set Fault Candidate Selection

DTIC Science & Technology

1989-09-01

Mark Herbst Mr. Paul Janusz Mr. Wayne Lee Ms. Patricia Lyon Ms. Sharyn McDowell Mr. Richard Payne Ms. Elizabeth Parliman Mr. Albert Stanbury Ms. Allison...SMCAR-ESP-L AMSMC-QA(R) AMSMC-QAK-B(R), R. Fer Rock Island, IL 61299-6000 28 Commander U.S. Army Materiel Command ATTN: AMCQA-E, Mr. Chris Neubert AMCPD...ATTN: AMSEL-PA-MT-S, Mr. Paul Kogut Mr. Andy Mills AMSEL-PA AMSEL-PA-DL AMSEL-RD-SE-CRM-CM AMSEL-RD-SE-AST Ft. Monmouth, NJ 07703-5023 35 Director U.S

Cubature on Wiener Space: Pathwise Convergence

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bayer, Christian, E-mail: christian.bayer@wias-berlin.de; Friz, Peter K., E-mail: friz@math.tu-berlin.de

2013-04-15

Cubature on Wiener space (Lyons and Victoir in Proc. R. Soc. Lond. A 460(2041):169-198, 2004) provides a powerful alternative to Monte Carlo simulation for the integration of certain functionals on Wiener space. More specifically, and in the language of mathematical finance, cubature allows for fast computation of European option prices in generic diffusion models.We give a random walk interpretation of cubature and similar (e.g. the Ninomiya-Victoir) weak approximation schemes. By using rough path analysis, we are able to establish weak convergence for general path-dependent option prices.

Adventures in Infectious Diseases

ScienceCinema

Fisher-Hoch, Susan [University of Texas School of Public Health

2018-04-25

Dr. Susan Fisher-Hoch, Virologist and Epidemiologist, will discuss her research and travels associated with viral hemorrhagic fevers. From the Ebola outbreak in Reston, Virginia to outbreaks of Crimean Congo Hemorrhagic Fever in South Africa, Senegal, and Saudi Arabia, Dr. Fisher-Hoch has studied and tracked the pathophysiology of these viral diseases. These studies have led her from the Center for Disease Control in the United States, to Lyon, France where she was instrumental in designing, constructing, and rendering operational a laboratory capable of containing some of the world's most dangerous diseases.

Orthostatic hypotension

NASA Technical Reports Server (NTRS)

Ninet, J.

1981-01-01

Basic orientation of the article, by the leader of a group of medical researchers associated with hospitals in Lyon, France, is toward definition and classification. A table divides OH (orthostatic hypotension) according to physiopathological classification into sympathicotonic and asympathicotonic types and then each of these into primary and secondary with subdivisions. The figure sketches organization and functioning of the baroreflex arc. Applications to clinical study of circulatory reflexes, listing measurement tests and the biological study of hormonal regulation listing the appropriate kinds of studies. Data are not given.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fisher-Hoch, Susan

Dr. Susan Fisher-Hoch, Virologist and Epidemiologist, will discuss her research and travels associated with viral hemorrhagic fevers. From the Ebola outbreak in Reston, Virginia to outbreaks of Crimean Congo Hemorrhagic Fever in South Africa, Senegal, and Saudi Arabia, Dr. Fisher-Hoch has studied and tracked the pathophysiology of these viral diseases. These studies have led her from the Center for Disease Control in the United States, to Lyon, France where she was instrumental in designing, constructing, and rendering operational a laboratory capable of containing some of the world's most dangerous diseases.

MarsSI: Martian surface data processing information system

NASA Astrophysics Data System (ADS)

Quantin-Nataf, C.; Lozac'h, L.; Thollot, P.; Loizeau, D.; Bultel, B.; Fernando, J.; Allemand, P.; Dubuffet, F.; Poulet, F.; Ody, A.; Clenet, H.; Leyrat, C.; Harrisson, S.

2018-01-01

MarsSI (Acronym for Mars System of Information, https://emars.univ-lyon1.fr/MarsSI/, is a web Geographic Information System application which helps managing and processing martian orbital data. The MarsSI facility is part of the web portal called PSUP (Planetary SUrface Portal) developed by the Observatories of Paris Sud (OSUPS) and Lyon (OSUL) to provide users with efficient and easy access to data products dedicated to the martian surface. The portal proposes 1) the management and processing of data thanks to MarsSI and 2) the visualization and merging of high level (imagery, spectral, and topographic) products and catalogs via a web-based user interface (MarsVisu). The portal PSUP as well as the facility MarsVisu is detailed in a companion paper (Poulet et al., 2018). The purpose of this paper is to describe the facility MarsSI. From this application, users are able to easily and rapidly select observations, process raw data via automatic pipelines, and get back final products which can be visualized under Geographic Information Systems. Moreover, MarsSI also contains an automatic stereo-restitution pipeline in order to produce Digital Terrain Models (DTM) on demand from HiRISE (High Resolution Imaging Science Experiment) or CTX (Context Camera) pair-images. This application is funded by the European Union's Seventh Framework Programme (FP7/2007-2013) (ERC project eMars, No. 280168) and has been developed in the scope of Mars, but the design is applicable to any other planetary body of the solar system.

Young children's non-numerical ordering ability at the start of formal education longitudinally predicts their symbolic number skills and academic achievement in maths.

PubMed

O'Connor, Patrick A; Morsanyi, Kinga; McCormack, Teresa

2018-01-25

Ordinality is a fundamental feature of numbers and recent studies have highlighted the role that number ordering abilities play in mathematical development (e.g., Lyons et al., ), as well as mature mathematical performance (e.g., Lyons & Beilock, ). The current study tested the novel hypothesis that non-numerical ordering ability, as measured by the ordering of familiar sequences of events, also plays an important role in maths development. Ninety children were tested in their first school year and 87 were followed up at the end of their second school year, to test the hypothesis that ordinal processing, including the ordering of non-numerical materials, would be related to their maths skills both cross-sectionally and longitudinally. The results confirmed this hypothesis. Ordinal processing measures were significantly related to maths both cross-sectionally and longitudinally, and children's non-numerical ordering ability in their first year of school (as measured by order judgements for everyday events and the parents' report of their child's everyday ordering ability) was the strongest longitudinal predictor of maths one year later, when compared to several measures that are traditionally considered to be important predictors of early maths development. Children's everyday ordering ability, as reported by parents, also significantly predicted growth in formal maths ability between Year 1 and Year 2, although this was not the case for the event ordering task. The present study provides strong evidence that domain-general ordering abilities play an important role in the development of children's maths skills at the beginning of formal education. © 2018 John Wiley & Sons Ltd.

Prevalence and associated factors of early repolarization pattern in healthy young northeastern Thai men: A correlation study with Brugada electrocardiography

PubMed Central

Makarawate, Pattarapong; Chaosuwannakit, Narumol; Ruamcharoen, Yossavadee; Panthongviriyakul, Aunejit; Pongchaiyakul, Choowong; Tharaksa, Prapapan; Sripo, Temsiri; Sawanyawisuth, Kittisak

2015-01-01

Background Early repolarization pattern (ERP) is characterized by J-point elevation with QRS notching or slurring in the terminal portion of the QRS complex. It may be associated with sudden death. Brugada syndrome (BS) is a genetic and fatal disease commonly found in northeastern Thai men. Data on the rate and predictors of ERP in Asian populations are limited. In addition, the correlation between ERP and BS has never been studied in an endemic area of BS. This study aimed to evaluate the prevalence of ERP and its associated factors in young, healthy male Asian subjects. Methods Between June 2011 and May 2012, 282 young, healthy men aged 20–45 years were enrolled at check-up clinics in Khon Kaen, Thailand. Subjects were divided into the ERP and non-ERP groups. Results There were 29 subjects with ERP (10.3%). The Sokolow–Lyon index was an independent factor for ERP with an adjusted odds ratio of 1.090 (95% CI: 1.027, 1.159). The Brugada ECG pattern was found in 11 (37.9%) subjects in the ERP group. The Brugada ECG pattern (non-type 1) was commonly found in lateral ERP patients. After the placement of high intercostal leads, the Brugada ECG pattern was dramatically increased compared with results obtained during standard ECG lead placement. Conclusions The ERP rate in young, healthy men from northeastern Thailand was 10.3%. A higher Sokolow–Lyon index was the only independent factor associated with ERP. Subjects with ERP should be examined with high intercostal leads to uncover Brugada ECG. PMID:26336562

Immunogenicity and safety of Intanza(®)/IDflu(®) intradermal influenza vaccine in South Korean adults: a multicenter, randomized trial.

PubMed

Hoon Han, Sang; Hee Woo, Jun; Weber, Francoise; Joo Kim, Woo; Ran Peck, Kyong; Il Kim, Sang; Hwa Choi, Young; Myung Kim, June

2013-09-01

Intanza(®)/IDflu(®) (Sanofi Pasteur, Lyon, France) is an intradermal inactivated trivalent influenza vaccine developed as an alternative to intramuscular influenza vaccine. The objective of this study was to confirm the immunogenicity and safety of Intanza/IDflu in South Korean adults. In a phase IV multicenter trial, South Korean adults 18-59 y old (n = 120) and ≥ 60 y old (n = 120) were randomized 1:1 to receive a single dose of Intanza/IDflu (9 µg for 18-59 y, 15 µg for ≥ 60 y) or trivalent intramuscular vaccine (Vaxigrip(®) 15 µg, Sanofi Pasteur, Lyon, France). Blood was collected on pre-vaccination (day 0) and on day 21. Hemagglutination inhibition titers, seroprotection rates and seroconversion rates were determined on day 21. Geometric mean titers, seroprotection and seroconversion rates were similar between the intradermal and intramuscular vaccines in both age groups for all three vaccine strains (A/H1N1, A/H3N2 and B). Both vaccines met Committee for Medicinal Products for Human Use criteria for all three strains. Solicited systemic reactions of the intradermal groups were generally mild, transient, and similar to those of the intramuscular groups. Solicited injection site reactions were more frequent in the intradermal groups but were mostly mild, transient, and consisted mainly of pain, erythema, and pruritus. No treatment-related serious adverse events or other safety concerns were reported. These results confirm that Intanza/IDflu is an effective and well-tolerated alternative to IM influenza vaccination. (Clinicaltrials.gov NCT ID: NCT01215669).

Rehabilitation of adolescent idiopathic scoliosis: results of exercises and bracing from a series of clinical studies. Europa Medicophysica-SIMFER 2007 Award Winner.

PubMed

Negrini, S; Atanasio, S; Zaina, F; Romano, M

2008-06-01

Rehabilitation of adolescent idiopathic scoliosis (AIS) requires a careful choice from among the possible treatments, such as bracing and exercises, according to the patient's needs. According to the literature, there is little evidence regarding the efficacy of these rehabilitation instruments. During the past few years, a full series of studies has been carried out to investigate their efficacy. The aim of this paper was to summarize all these results. Three systematic reviews (two on exercises and one on manual therapy), and four cohort prospective studies were performed. The prospective studies included two trials with a prospective control group on exercises (one to avoid bracing and one in preparation to bracing) and two trials with retrospective control group on a new brace developed by the Authors (Sforzesco brace and SPoRT concept of correction versus Lyon brace and Risser cast). Results show that in literature there is proof of level 1b on exercises but no studies on manual therapy. High quality exercises like Scientific Exercises Approach to Scoliosis (SEAS) have more efficacy than usual physiotherapy, significantly reducing brace prescription in one year from 25% of cases to 6%. Moreover, such exercises help to obtain the best results in bracing first correction. The Sforzesco brace has proved to have more efficacy than the Lyon brace, whereas it has the same efficacy--but reduced side effects and impact on quality of life--than the Risser brace. With an efficient management of data collection, it is possible to develop a set of studies aimed at verifying the efficacy of clinical daily rehabilitation approaches.

La Moisissure et la Bactérie: Deconstructing the fable of the discovery of penicillin by Ernest Duchesne.

PubMed

Shama, Gilbert

2016-09-01

Ernest Duchesne (1874-1912) completed his thesis on microbial antagonism in 1897 in Lyon. His work lay unknown for fifty years, but on being brought to light led to his being credited with having discovered penicillin prior to Alexander Fleming. The claims surrounding Duchesne are examined here both from the strictly microbiological perspective, and also for what they reveal about how the process of discovery is frequently misconstrued. The combined weight of evidence presented here militates strongly against the possibility that the species of Penicillium that Duchesne worked with produced penicillin. Copyright © 2016 Elsevier Ltd. All rights reserved.

ArcCN-Runoff: An ArcGIS tool for generating curve number and runoff maps

USGS Publications Warehouse

Zhan, X.; Huang, M.-L.

2004-01-01

The development and the application of ArcCN-Runoff tool, an extension of ESRI@ ArcGIS software, are reported. This tool can be applied to determine curve numbers and to calculate runoff or infiltration for a rainfall event in a watershed. Implementation of GIS techniques such as dissolving, intersecting, and a curve-number reference table improve efficiency. Technical processing time may be reduced from days, if not weeks, to hours for producing spatially varied curve number and runoff maps. An application example for a watershed in Lyon County and Osage County, Kansas, USA, is presented. ?? 2004 Elsevier Ltd. All rights reserved.

[The 48,XXXX syndrome: study of psychomotor development from birth to 11 years of age and review of the literature].

PubMed

Plauchu, H; Ollagnon-Roman, E; Armand, J P; Robert, J M

1988-01-01

A child with four X chromosomes is described. This case and the literature review allow to underline the mental retardation and some other "major" but inconstant signs that are extremely helpful for the early clinical diagnosis. They are hypertelorism, epicanthal fold and genital anomalies. The mental evolution is assessed on an eleven year period. The bad results concern particularly the child's use of language and the complicated works. They become worse with time. The additional X chromosomes Mary Lyon inactivation, perhaps incomplete, is discussed because its determinism. Enzymatic measuring out is our approach to this problem.

Evolution of the architecture of the ATLAS Metadata Interface (AMI)

NASA Astrophysics Data System (ADS)

Odier, J.; Aidel, O.; Albrand, S.; Fulachier, J.; Lambert, F.

2015-12-01

The ATLAS Metadata Interface (AMI) is now a mature application. Over the years, the number of users and the number of provided functions has dramatically increased. It is necessary to adapt the hardware infrastructure in a seamless way so that the quality of service re - mains high. We describe the AMI evolution since its beginning being served by a single MySQL backend database server to the current state having a cluster of virtual machines at French Tier1, an Oracle database at Lyon with complementary replication to the Oracle DB at CERN and AMI back-up server.

MASTER-SAAO: contradictory SN and flaring OT

NASA Astrophysics Data System (ADS)

Balanutsa, P.; Lipunov, V.; Buckley, D.; Gorbovskoy, E.; Tiurina, N.; Kuznetsov, A.; Kornilov, V.; Gress, O.; Pogrosheva, T.; Shumkov, V.; Vladimirov, V.; Vlasenko, D.; Kuvshinov, D.; Gabovich, A.

2017-07-01

MASTER-SAAO auto-detection system ( Lipunov et al., "MASTER Global Robotic Net", Advances in Astronomy, 2010, 30L ) discovered OT source at (RA, Dec) = 03h 42m 50.70s , -01d 52m 28s.7 on 2017-07-01.1753UT with unfiltered (6 images), that contradicts to Ia type detected in ATEL #10240 , ATEL #10225 for ATLAS17dcl ( http://www.supernova.thistlethwaites.com/sn2017/sndate.html ). It is in 8.4"W,20"S of PGC135685 with Btc=15.13, Vgsr=2773 http://leda.univ-lyon1.fr/ledacat.cgi?PGC135685 Spectral observations are required.

KSC-04PD-1878

NASA Technical Reports Server (NTRS)

2004-01-01

KENNEDY SPACE CENTER, FLA. At KSCs annual Hispanic American Heritage luncheon, contractor sponsors were presented certificates of appreciation. Accepting were (from left) Dick Lyons, with ASRC Aerospace Corp.; Tom Niemeyer, with InDyne Corp.; Kevin Hoshstrasser (with Boeing); Vera Pettis, with Lockheed Martin; and Bill Sample, with SGS. Next to them are astronaut Fernando Caldeiro, Felix A. Soto Toro and Joseph Tellado. Soto Toro and Tellado were co-chairs of the event hosted by the Hispanic Employment Program Working Group. The annual event helps employees reflect on the extensive contributions Hispanics have made to KSC, NASA and the nation.

Gamma ray flashes add to mystery of upper atmosphere

NASA Astrophysics Data System (ADS)

Atmospheric electricity research has come a long way since Benjamin Franklin's kite-flying days. But what researchers have been learning lately about above-thunderstorm electricity has wrought a whole new era of mysteries.For a start, last summer a Colorado meteorologist sparked interest in a terrestrial phenomenon that the community first observed more than 100 years ago: optical flashes that occur above thunderstorms—at least 30 km above Earth. Walter Lyons with the Ft. Collins-based Mission Research Corporation, demonstrated that such flashes are not anomalies, as conventional scientific wisdom had held. He filmed hundreds of flashes during a 2-week period.

Acceptance of the 2015 C.C. Patterson Award by Karen H. Johannesson

NASA Astrophysics Data System (ADS)

Johannesson, Karen H.

2016-01-01

First and foremost I want to thank Berry Lyons, who obviously couldn't be here today, for nominating me for this prestigious award, and for his very complimentary citation. Thank you so much, Berry! Berry is one of the most generous people I have ever met, and it was definitely one of the best decisions I ever made to follow him to the University of Nevada to work with him on my Ph.D. I also wish to thank my friend and colleague Robyn Hannigan for being here today to read the citation in Berry's stead.

Pore Pressure Diffusion as a possible mechanism for the Ag. Ioanis 2001 earthquake swarm activity (Gulf of Corinth, Central Greece).

NASA Astrophysics Data System (ADS)

Vallianatos, F.; Michas, G.; Papadakis, G.; Sammonds, P.

2012-04-01

The Gulf of Corinth rift (Central Greece) is one of the most seismotectonically active areas in Europe (Ambraseys and Jackson, 1990; 1997), with an important continental N-S extension of about 13 mm/yr and 6 mm/yr at the west and east part respectively (Clarke et al., 1997a). The seismicity of the area includes 5 main earthquakes of magnitude greater than 5.8 since 1960. In the western part of the rift, where the extension reaches its maximum value, earthquake swarms are often being observed (Bourouis and Cornet, 2009). Such an earthquake crisis has been occurred on 2001 at the southern margin of the west part of the rift. The crisis lasted about 100 days with a major event the Ag. Ioanis earthquake (4.3 Mw) on 8th of April 2001 (Pacchiani and Lyon-Caen, 2010). The possible relation between fluids flow and the observed earthquake swarms at the west part of the Gulf of Corinth rift has been discussed in the works of Bourouis and Cornet (2009) and Pacchiani and Lyon-Caen (2010). In the present work we examine the spatiotemporal properties of the Ag. Ioanis 2001 earthquake swarm, using data from the CRL network (http://crlab.eu/). We connect these properties to a mechanism due to pore pressure diffusion (Shapiro et al., 1997) and we estimate the hydraulic diffusivity and the permeability of the surrounding rocks. A back front of the seismicity (Parotidis et al., 2004) is also been observed, related to the migration of seismicity and the development of a quiescence region near the area of the initial pore pressure perturbation. Moreover, anisotropy of the hydraulic diffusivity has been observed, revealing the heterogeneity of the surrounding rocks and the fracture systems. This anisotropy is consistent in direction with the fault zone responsible for the Ag. Ioanis earthquake (Pacchiani and Lyon-Caen, 2010). Our results indicate that fluids flow and pore pressure perturbations are possible mechanisms for the initiation and the evolution of the Ag. Ioanis 2001

ULF wave analysis and radial diffusion calculation using a global MHD model for the 17 March 2013 and 2015 storms

NASA Astrophysics Data System (ADS)

Li, Zhao; Hudson, Mary; Patel, Maulik; Wiltberger, Michael; Boyd, Alex; Turner, Drew

2017-07-01

The 17 March 2015 St. Patrick's Day Storm is the largest geomagnetic storm to date of Solar Cycle 24, with a Dst of -223 nT. The magnetopause moved inside geosynchronous orbit under high solar wind dynamic pressure and strong southward interplanetary magnetic field Bz causing loss; however, a subsequent drop in pressure allowed for rapid rebuilding of the radiation belts. The 17 March 2013 storm also shows similar effects on outer zone electrons: first, a rapid dropout due to inward motion of the magnetopause followed by rapid increase in flux above the prestorm level early in the recovery phase and a slow increase over the next 12 days. These phases can be seen in temporal evolution of the electron phase space density measured by the Energetic Particle, Composition, and Thermal Plasma Suite (ECT) instruments on Van Allen Probes. Using the Lyon-Fedder-Mobarry global MHD model driven by upstream solar wind measurements, we simulated both St. Patrick's Day 2013 and 2015 events, analyzing Lyon-Fedder-Mobarry electric and magnetic fields to calculate radial diffusion coefficients. These coefficients have been implemented in a radial diffusion code, using the measured electron phase space density following the local heating as the initial radial profile and outer boundary condition for subsequent temporal evolution over the next 12 days, beginning 18 March. Agreement with electron phase space density at 1000 MeV/G measured by the MagEIS component of the ECT instrument suite on Van Allen Probes was much improved using radial diffusion coefficients from the MHD simulations relative to coefficients parameterized by a global geomagnetic activity index.

Exceptional warming in the Western Pacific-Indian Ocean warm pool has contributed to more frequent droughts in eastern Africa

USGS Publications Warehouse

Funk, Christopher C.; Peterson, Thomas C.; Stott, Peter A.; Herring, Stephanie

2012-01-01

In 2011, East Africa faced a tragic food crisis that led to famine conditions in parts of Somalia and severe food shortages in parts of Ethiopia and Somalia. While many nonclimatic factors contributed to this crisis (high global food prices, political instability, and chronic poverty, among others) failed rains in both the boreal winter of 2010/11 and the boreal spring of 2011 played a critical role. The back-to-back failures of these rains, which were linked to the dominant La Niña climate and warm SSTs in the central and southeastern Indian Ocean, were particularly problematic since they followed poor rainfall during the spring and summer of 2008 and 2009. In fact, in parts of East Africa, in recent years, there has been a substantial increase in the number of below-normal rainy seasons, which may be related to the warming of the western Pacific and Indian Oceans (for more details, see Funk et al. 2008; Williams and Funk 2011; Williams et al. 2011; Lyon and DeWitt 2012). The basic argument of this work is that recent warming in the Indian–Pacific warm pool (IPWP) enhances the export of geopotential height energy from the warm pool, which tends to produce subsidence across eastern Africa and reduce onshore moisture transports. The general pattern of this disruption has been supported by canonical correlation analyzes and numerical experiments with the Community Atmosphere Model (Funk et al. 2008), diagnostic evaluations of reanalysis data (Williams and Funk 2011; Williams et al. 2011), and SST-driven experiments with ECHAM4.5, ECHAM5, and the Community Climate Model version 3 (CCM3.6) (Lyon and DeWitt 2012).

On-Line Allocation Of Robot Resources To Task Plans

NASA Astrophysics Data System (ADS)

Lyons, Damian M.

1989-02-01

In this paper, I present an approach to representing plans that make on-line decisions about resource allocation. An on-line decision is the evaluation of a conditional expression involving sensory information as the plan is being executed. I use a plan representation called 7ZS10'1 1,12that has been especially designed for the domain of robot programming, and in particular, for the problem of on-line decisions. The resource allocation example is based on the robot assembly cell architecture outlined by Venkataraman and Lyons16. I begin by setting forth a definition of on-line decision making and some arguments as to why this form of decision making is important and useful. To set the context for the resource allocation example, I take some care in categorizing the types of on-line decision making and the approaches adopted by other workers so far. In particular, I justify a plan-based approach to the study of on-line decision making. From that, the focus shifts to one type of decision making: on-line allocation of robot resources to task plans. Robot resources are the physical manipulators (grippers, wrists, arms, feeders, etc) that are available to carry out the task. I formulate the assembly cell architecture of Venkataraman and Lyons16 as an R.S plan schema, and show how the on-line allocation specified in that architecture can be implemented. Finally, I show how considering the on-line allocation of logical resources, that is a physical resource plus some model information, can be used as a non-traditional approach to some problems in robot task planning.

Electrocardiographic Criteria for Left Ventricular Hypertrophy in Asians Differs from Criteria Derived from Western Populations--Community-based Data from an Asian Population.

PubMed

Xu, Chang Fen; Tan, Eugene S J; Feng, Liang; Santhanakrishnan, Rajalakshmi; Chan, Michelle M Y; Nyunt, Shwe Zin; Ng, Tze Pin; Ling, Lieng Hsi; Richards, A Mark; Lam, Carolyn S P; Lim, Toon Wei

2015-08-01

Electrocardiographic (ECG) criteria for left ventricular hypertrophy (LVH), such as the Cornell and Sokolow-Lyon voltage criteria were derived from Western populations. However, their utility and accuracy for diagnosing echocardiographic LVH in Asian populations is unclear. The objective of this study was to assess the accuracy of ECG criteria for LVH in Asians and to determine if alternative gender-specific ECG cut-offs may improve its diagnostic accuracy. ECG and echocardiographic assessments were performed on 668 community-dwelling Asian adults (50.9% women; 57 ± 10 years) in Singapore. The accuracy of ECG voltage criteria was compared to echocardiographic LVH criteria based on the American Society of Echocardiography guidelines, and Asian ethnicity and gender-specific partition values. Echocardiographic LVH was present in 93 (13.6%) adults. Cornell criteria had low sensitivity (5.5%) and high specificity (98.9%) for diagnosing LVH. Modified gender specific cut-offs (18 mm in women, 22 mm in men) improved sensitivity (8.8% to 17.5%, 0% to 14.7%, respectively) whilst preserving specificity (98.2% to 94.2%, 100% to 95.8%). Similarly, Sokolow-Lyon criteria had poor sensitivity (7.7%) and high specificity (96.1%) for diagnosing LVH. Lowering the cut-off value from 35 mm to 31 mm improved the sensitivity in women from 3.5% to 14% while preserving specificity at 94.2%. A cut-off of 36 mm was optimal in men (sensitivity of 14.7%, specificity of 95.5%). Current ECG criteria for LVH derived in Western cohorts have limited sensitivity in Asian populations. Our data suggests that ethnicity- and gender-specific ECG criteria may be needed.

Partial Life History of Chrysodeixis includens (Lepidoptera: Noctuidae) on Summer Hosts.

PubMed

Moonga, M N; Davis, J A

2016-08-01

The soybean looper, Chrysodeixis includens (Walker) (Lepidoptera: Noctuidae), is a major defoliating pest of soybeans, Glycine max (L.) Merrill, in Louisiana. However, other alternate host crops in the agroecosystem have the potential to impact C. includens populations. Life table statistics of C. includens on four host plants were evaluated. C. includens larvae were fed leaves of three cotton Gossypium hirsutum L. cultivars 'DP 143 B2RF,' 'DP 174 RF,' and 'PHY 485 WRF'; cowpea Vigna unguiculata (L.) Walpers 'California Blackeye'; three soybean cultivars 'Lyon,' 'PI 227687,' and 'RC 4955'; and sweetpotato Ipomoea batatas (L.) Lamarck 'Evangeline.' All C. includens larvae reared on cotton cultivars DP 143 B2RF and PHY 485 WRF experienced 100% mortality during the first instar. Total developmental period of preadult C. includens was significantly shorter on cotton DP 174 RF and cowpea California Blackeye but longer on sweetpotato Evangeline. Sweetpotato Evangeline had the highest amount of leaf tissue consumed and soybean Lyon had the least. Pupal weight was highest when insects fed on cotton DP 174 RF and lowest on soybean PI 227687. Life table statistics showed that the highest intrinsic rate of increase and net reproductive rate were attained when insects were reared on cotton DP 174 RF and cowpea California Blackeye whilst the lowest were recorded on soybean PI 227687. This study provides valuable information on the role of alternative host crops on the partial life history of C. includens in Louisiana agroecosystems. © The Authors 2016. Published by Oxford University Press on behalf of Entomological Society of America. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

Four ECG left ventricular hypertrophy criteria and the risk of cardiovascular events and mortality in patients with vascular disease.

PubMed

van Kleef, Monique E A M; Visseren, Frank L J; Vernooij, Joris W P; Nathoe, Hendrik M; Cramer, Maarten-Jan M; Bemelmans, Remy H H; van der Graaf, Yolanda; Spiering, Wilko

2018-06-06

The relation between different electrocardiographic left ventricular hypertrophy (ECG-LVH) criteria and cardiovascular risk in patients with clinical manifest arterial disease is unclear. Therefore, we determined the association between four ECG-LVH criteria: Sokolow-Lyon, Cornell product, Cornell/strain index and Framingham criterion; and risk of cardiovascular events and mortality in this population. Risk of cardiovascular events was estimated in 6913 adult patients with clinical manifest arterial disease originating from the Secondary Manifestations of ARTerial disease (SMART) cohort. Cox proportional regression analysis was used to estimate the risk of the four ECG-LVH criteria and the primary composite outcome: myocardial infarction (MI), stroke or cardiovascular death; and secondary outcomes: MI, stroke and all-cause mortality; adjusted for confounders. The highest prevalence of ECG-LVH was observed for Cornell product (10%) and Cornell/strain index (9%). All four ECG-LVH criteria were associated with an increased risk of the primary composite endpoint: Sokolow-Lyon (hazard ratio 1.37, 95% CI 1.13-1.66), Cornell product (hazard ratio 1.54, 95% CI 1.30-1.82), Cornell/strain index (hazard ratio 1.70, 95% CI 1.44-2.00) and Framingham criterion (hazard ratio 1.78, 95% CI 1.21-2.62). Cornell product, Cornell/strain index and Framingham criterion ECG-LVH were additionally associated with an elevated risk of secondary outcomes. Cardiovascular risk increased whenever two, or three or more ECG-LVH criteria were present concurrently. All four ECG-LVH criteria are associated with an increased risk of cardiovascular events. As Cornell/strain index is both highly prevalent and carries a high cardiovascular risk, this is likely the most relevant ECG-LVH criterion for clinical practice.

MUSE optical alignment procedure

NASA Astrophysics Data System (ADS)

Laurent, Florence; Renault, Edgard; Loupias, Magali; Kosmalski, Johan; Anwand, Heiko; Bacon, Roland; Boudon, Didier; Caillier, Patrick; Daguisé, Eric; Dubois, Jean-Pierre; Dupuy, Christophe; Kelz, Andreas; Lizon, Jean-Louis; Nicklas, Harald; Parès, Laurent; Remillieux, Alban; Seifert, Walter; Valentin, Hervé; Xu, Wenli

2012-09-01

MUSE (Multi Unit Spectroscopic Explorer) is a second generation VLT integral field spectrograph (1x1arcmin² Field of View) developed for the European Southern Observatory (ESO), operating in the visible wavelength range (0.465-0.93 μm). A consortium of seven institutes is currently assembling and testing MUSE in the Integration Hall of the Observatoire de Lyon for the Preliminary Acceptance in Europe, scheduled for 2013. MUSE is composed of several subsystems which are under the responsibility of each institute. The Fore Optics derotates and anamorphoses the image at the focal plane. A Splitting and Relay Optics feed the 24 identical Integral Field Units (IFU), that are mounted within a large monolithic instrument mechanical structure. Each IFU incorporates an image slicer, a fully refractive spectrograph with VPH-grating and a detector system connected to a global vacuum and cryogenic system. During 2011, all MUSE subsystems were integrated, aligned and tested independently in each institute. After validations, the systems were shipped to the P.I. institute at Lyon and were assembled in the Integration Hall This paper describes the end-to-end optical alignment procedure of the MUSE instrument. The design strategy, mixing an optical alignment by manufacturing (plug and play approach) and few adjustments on key components, is presented. We depict the alignment method for identifying the optical axis using several references located in pupil and image planes. All tools required to perform the global alignment between each subsystem are described. The success of this alignment approach is demonstrated by the good results for the MUSE image quality. MUSE commissioning at the VLT (Very Large Telescope) is planned for 2013.

[Alberic Pont, the great war and the "broken faces"].

PubMed

Sigaux, N; Amiel, M; Piotrovitch d'Orlik, S; Breton, P

2017-12-01

The First World War and the number of facial injuries made specialized trauma centers necessary. Alberic Pont was trained both in medicine and dentistry. He founded in Lyon one of the first French specialized wards, which received more than 7000 soldiers overall. Through his charisma, his skills, his creativity and his generosity, he must be considered as a symbol among the pioneers of maxillo-facial surgery, which was then at its early stage. The centenary of World War I is the occasion to shed light on this man who dedicated his career to those who were renamed "broken faces". Copyright © 2017 Elsevier Masson SAS. All rights reserved.

A new species of Platyrrhinus (Chiroptera: Phyllostomidae) from western Colombia and Ecuador, with emended diagnoses of P. aquilus, P. dorsalis, and P. umbratus

USGS Publications Warehouse

Velazco, Paúl M.; Gardner, Alfred L.

2009-01-01

The Neotropical bat genus Platyrrhinus (Chiroptera: Phyllostomidae: Stenodermatinae) currently comprises 15 species. Our morphological and morphometric analysis of large and medium-sized Platyrrhinus revealed a distinctive Undescribed species from western South America. We also recognize P. aquilus (Handley & Ferris 1972) and P. umbratus (Lyon 1902) as valid species. We describe P. nitelinea sp. nov. from western Colombia and Ecuador and provide emended diagnoses along with descriptions of P. aquilus, P.. dorsalis, and P. umbratus. Phylogenetic analysis of Platyrrhinus based on morphological characters indicates that P. aquilus is closely related to P. aurarius and P. nigellus, P. umbratus to P. chocoensis, and P. nitelinea to P. vittatus.

The neurobiology of the stress-resistant brain

PubMed Central

FLESHNER, MONIKA; MAIER, STEVEN F.; LYONS, DAVID M.; RASKIND, MURRAY A.

2012-01-01

The 2010 Neurobiology of Stress Workshop brought together scientists from all over the world to share and discuss their results from studies examining the consequences of acute, repeated, and chronic stressor exposure on health and disease. Session IV entitled “The neurobiology of the stress-resistant brain” explored how we can intervene to promote stress resistance and stress resilience. Four scientists, who explore this topic from unique and convergent perspectives, presented their experimental results derived from studies in rat (Fleshner and Maier), non-human primates (Lyons), and human (Raskind). Summaries of each presentation, supporting publications, and overall take-home messages from the session are presented. PMID:21790482

Déprescription des agonistes des récepteurs des benzodiazépines

PubMed Central

Pottie, Kevin; Thompson, Wade; Davies, Simon; Grenier, Jean; Sadowski, Cheryl A.; Welch, Vivian; Holbrook, Anne; Boyd, Cynthia; Swenson, Robert; Ma, Andy; Farrell, Barbara

2018-01-01

Résumé Objectif Formuler des lignes directrices fondées sur les données probantes visant à aider les cliniciens à décider du moment et de la façon sécuritaire de réduire la dose des agonistes des récepteurs des benzodiazépines (BZRA) pour mettre fin au traitement; se concentrer sur le niveau le plus élevé des données disponibles et obtenir les commentaires des professionnels de première ligne durant le processus de rédaction, de révision et d’adoption des lignes directrices. Méthodes L’équipe comptait 8 cliniciens (1 médecin de famille, 2 psychiatres, 1 psychologue clinique, 1 pharmacologue clinique, 2 pharmaciennes cliniques et 1 gériatre) et une spécialiste de la méthodologie; les membres ont divulgué tout conflit d’intérêts. Nous avons eu recours à un processus systématique, y compris l’approche GRADE (Grading of Recommendations Assessment, Development and Evaluation) pour formuler les lignes directrices. Les données ont été générées par une revue systématique d’études portant sur la déprescription des BZRA contre l’insomnie, de même que par une revue des revues sur les torts liés à la poursuite du traitement par BZRA et des synthèses narratives sur les préférences des patients et les répercussions sur les ressources. Ces données et le score GRADE de qualité des données ont servi à formuler les recommandations. L’équipe a peaufiné le texte sur le contenu et les recommandations des lignes directrices par consensus et a synthétisé les considérations cliniques afin de répondre aux questions des cliniciens de première ligne. Une version préliminaire des lignes directrices a été révisée par les cliniciens et les intervenants. Recommandations Nous recommandons d’offrir la déprescription (réduction lente de la dose) des BZRA à tous les patients âgés (≥ 65 ans) sous un BZRA, sans égard à la durée de l’usage, et suggérons d’offrir la déprescription (réduction lente de la dose) �

Occurrence of ground waters of low hardness and of high chloride content in Lyon County, Minnesota

USGS Publications Warehouse

Rodis, Harry G.; Schneider, Robert

1960-01-01

Hardness and chloride determinations were made with field-testing kits at the time data were obtained on most of the farm wells in the county. Tests were made on wells that were reported to yield relatively soft or "salty" water.

Diversity among strains of Pseudomonas aeruginosa from manure and soil, evaluated by multiple locus variable number tandem repeat analysis and antibiotic resistance profiles.

PubMed

Youenou, Benjamin; Brothier, Elisabeth; Nazaret, Sylvie

2014-01-01

The results of a multiple locus variable number of tandem repeat (VNTR) analysis (MLVA)-based study designed to understand the genetic diversity of soil and manure-borne Pseudomonas aeruginosa isolates, and the relationship between these isolates and a set of clinical and environmental isolates, are hereby reported. Fifteen described VNTR markers were first selected, and 62 isolates recovered from agricultural and industrial soils in France and Burkina Faso, and from cattle and horse manure, along with 26 snake-related isolates and 17 environmental and clinical isolates from international collections, were genotyped. Following a comparison with previously published 9-marker MLVA schemes, an optimal 13-marker MLVA scheme (MLVA13-Lyon) was identified that was found to be the most efficient, as it showed high typability (90%) and high discriminatory power (0.987). A comparison of MLVA with PFGE for typing of the snake-related isolates confirmed the MLVA13-Lyon scheme to be a robust method for quickly discriminating and inferring genetic relatedness among environmental isolates. The 62 isolates displayed wide diversity, since 41 MLVA types (i.e. MTs) were observed, with 26 MTs clustered in 10 MLVA clonal complexes (MCs). Three and eight MCs were found among soil and manure isolates, respectively. Only one MC contained both soil and manure-borne isolates. No common MC was observed between soil and manure-borne isolates and the snake-related or environmental and clinical isolates. Antibiotic resistance profiles were performed to determine a potential link between resistance properties and the selective pressure that might be present in the various habitats. Except for four soil and manure isolates resistant to ticarcillin and ticarcillin/clavulanic acid and one isolate from a hydrocarbon-contaminated soil resistant to imipenem, all environmental isolates showed wild-type antibiotic profiles. Copyright © 2013 Institut Pasteur. Published by Elsevier Masson SAS. All rights

Air quality and social deprivation in four French metropolitan areas – A localized spatiotemporal environmental inequality analysis

PubMed Central

Padilla, Cindy M; Kihal-Talantikite, Wahida; Vieira, Verónica. M; Rosselo, Philippe; LeNir, Geraldine; Zmirou-Navier, Denis; Deguen, Severine

2015-01-01

Several studies have documented that more deprived populations tend to live in areas characterized by higher levels of environmental pollution. Yet, time trends and geographic patterns of this disproportionate distribution of environmental burden remain poorly assessed, especially in Europe. We investigated the spatial and temporal relationship between ambient air nitrogen dioxide (NO2) concentrations and socioeconomic and demographic data in four French Metropolitan Areas (Lille in the north, Lyon in the center, Marseille in the south, and Paris) during two different time periods. The geographical unit used was the census block. The dependent variable was the NO2 annual average concentration (µg/m3) per census block, and the explanatory variables were a neighborhood deprivation index and socioeconomic and demographic data derived from the national census. Generalized additive models were used to account for spatial autocorrelation. We found that the strength and direction of the association between deprivation and NO2 estimates varied between cities. In Paris, census blocks with the higher social categories are exposed to higher mean concentrations of NO2. However, in Lille and Marseille, the most deprived census blocks are the most exposed to NO2. In Lyon, the census blocks in the middle social categories were more likely to have higher concentrations than in the lower social categories. Despite a general reduction in NO2 concentrations over the study period in the four metropolitan areas, we found contrasting results in the temporal trend of environmental inequalities. There is clear evidence of city-specific spatial and temporal environmental inequalities that relate to the historical socioeconomic make-up of the cities and its evolution. Hence, general statements about environmental and social inequalities may not properly characterize situations where people of higher social status find the benefits of living in a specific city outweigh the detriment of

[Left ventricular hypertrophy in black African subjects with artery hypertension: Results of a cross-sectional survey conducted in semi-rural area in Senegal].

PubMed

Mbaye, A; Dodo, B; Ngaïde, A A; Sy, N F; Babaka, K; Mingou, J S; Faye, M; Niang, K; Sarr, S A; Dioum, M; Bodian, M; Ndiaye, M B; Kane, A D; Ndour-Mbaye, M; Diao, M; Diack, B; Kane, M; Diagne-Sow, D; Thiaw, I; Kane, A

2017-09-01

To assess the prevalence of left ventricular hypertrophy according to electrocardiographic and echocardiographic criteria among hypertensive patients living in semi-rural Senegalese area. According to the World Health Organization STEPSwise approach, we conducted, in November 2012, a cross-sectional and exhaustive study in the population aged at least 35 years old and living for at least six months in the semi-rural area of Guéoul. We researched electrocardiographic and echocardiographic left ventricular hypertrophy in hypertensive subjects. Data were analyzed with SPSS 18.0 software version. The significance level was agreed for a value of P<0.05. We examined 1411 subjects aged on average of 48.5±12.7 years. In total, 654 subjects were hypertensive and screening of left ventricular hypertrophy (LVH) was effective in 515 of them. According to Sokolow-Lyon index, 86 subjects (16.7%) presented electrocardiographic LVH, more frequently in men (P=0.002). According to Cornell index and Cornell product, LVH was founded respectively in 66 (12.8%) and 52 subjects (10.1%), more frequently in female (P=0.0001; P=0.004). It was more common in grade 3 of hypertension however criteria. In echocardiography, prevalence of LVH was 2.2% (13 cases) according to the left ventricular mass, 9.3% (48 cases) according to the left ventricular mass indexed to body surface area and 8.2% (42 cases) according to the left ventricular mass indexed to height 2.7 . LVH was significantly correlated with the electrocardiographic LVH according to Sokolow-Lyon index (P<0.0001) and the grade 3 of hypertension (P=0.003). Although rare in hypertensive Senegalese living in semi-rural area, left ventricular hypertrophy is correlated with severity of grade of hypertension. Screening by electrocardiogram will allow better follow-up of these hypertensive subjects. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

LONG-TERM EFFECTS OF CHLORTHALIDONE VS HYDROCHLOROTHIAZIDE ON ELECTROCARDIOGRAPHIC LEFT VENTRICULAR HYPERTROPHY IN THE MULTIPLE RISK FACTOR INTERVENTION TRIAL

PubMed Central

Ernst, Michael E.; Neaton, James D.; Grimm, Richard H.; Collins, Gary; Thomas, William; Soliman, Elsayed Z.; Prineas, Ronald J.

2011-01-01

Chlorthalidone (CTD) reduces 24-hour blood pressure more effectively than hydrochlorothiazide (HCTZ), but whether this influences electrocardiographic left ventricular hypertrophy (LVH) is uncertain. One source of comparative data is the Multiple Risk Factor Intervention Trial (MRFIT), which randomly assigned 8,012 hypertensive men to special intervention (SI) or usual care (UC). SI participants could use CTD or HCTZ initially; previous analyses have grouped clinics by their main diuretic used (C-clinics: CTD; H-clinics: HCTZ). After 48 months, SI participants receiving HCTZ were recommended to switch to CTD, in part, because higher mortality was observed for SI compared to UC participants in H-clinics, while the opposite was found in C-clinics. In this analysis, we examined change in continuous measures of electrocardiographic LVH using both an ecologic analysis by previously-reported C- or H-clinic groupings, and an individual participant analysis where use of CTD or HCTZ by SI participants was considered and updated annually. Through 48 months, differences between SI and UC in LVH were larger for C-clinics compared to H-clinics (Sokolow-Lyon: −93.9 vs −54.9 μV, P=0.049; Cornell voltage: −68.1 vs −35.9 μV, P=0.019; Cornell voltage product: −4.6 vs −2.2 μV/ms, P=0.071; left ventricular mass: −4.4 vs −2.8 gm, P=0.002). At the individual participant level, Sokolow-Lyon and left ventricular mass were significantly lower for SI men receiving CTD compared to HCTZ through 48 months and 84 months of follow-up. Our findings on LVH support the idea that greater blood pressure reduction with CTD than HCTZ may have led to differences in mortality observed in MRFIT. PMID:22025372

Women in biomedical engineering and health informatics and its impact on gender representation for accepted publications at IEEE EMBC 2007.

PubMed

McGregor, Carolyn; Smith, Kathleen P; Percival, Jennifer

2008-01-01

The study of women within the professions of Engineering and Computer Science has consistently been found to demonstrate women as a minority within these professions. However none of that previous work has assessed publication behaviours based on gender. This paper presents research findings on gender distribution of authors of accepted papers for the IEEE Engineering and Medicine Society annual conference for 2007 (EMBC '07) held in Lyon, France. This information is used to present a position statement of the current state of gender representation for conference publication within the domain of biomedical engineering and health informatics. Issues in data preparation resulting from the lack of inclusion of gender in information gathered from accepted authors are presented and discussed.

Fall Chinook Salmon Survival and Supplementation Studies in the Snake River Reservoirs, 1996 Annual Report.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Williams, John G.; Bjornn

1998-05-01

In 1996, the National Marine Fisheries Service, the Nez Perce Tribe, and the U.S. Fish and Wildlife Service completed the second year of cooperative research to investigate migrational characteristics of subyearling fall chinook salmon in the Snake River Basin. In spring and early summer, we captured natural subyearling fall chinook salmon by beach seine, PIT tagged them, and released them in two reaches of the Snake River. Also, subyearling fall chinook salmon reared at Lyons Ferry Hatchery were PIT tagged at the hatchery, transported, and released weekly at Pittsburg Landing on the Snake River and Big Canyon Creek on themore » Clearwater River to collect data on survival detection probabilities, and travel time.« less

News from the Biological Stain Commission.

PubMed

Lyon, H O; Kiernan, J A

2008-12-01

In the three earlier editions of News from the Biological Stain Commission (BSC), under the heading of "Regulatory affairs," the BSC's International Affairs Committee reported on the work of Technical Committee 212, Clinical Laboratory Testing and in Vitro Diagnostic Test Systems of the International Standards Organization (ISO/TC 212) and its working groups, WG 1, WG 2 and WG 3. In this issue of News from the BSC, H.O. Lyon provides information from the annual meeting of ISO/TC 212 that took place June 2-4, 2008 in Vancouver, British Columbia, Canada. In addition, under the heading of "Certification," J.A. Kiernan examines the certification procedure for thionine used by the BSC laboratory in Rochester, NY.

Laser speckle visibility acoustic spectroscopy in soft turbid media

NASA Astrophysics Data System (ADS)

Wintzenrieth, Frédéric; Cohen-Addad, Sylvie; Le Merrer, Marie; Höhler, Reinhard

2014-03-01

We image the evolution in space and time of an acoustic wave propagating along the surface of turbid soft matter by shining coherent light on the sample. The wave locally modulates the speckle interference pattern of the backscattered light and the speckle visibility[2] is recorded using a camera. We show both experimentally and theoretically how the temporal and spatial correlations in this pattern can be analyzed to obtain the acoustic wavelength and attenuation length. The technique is validated using shear waves propagating in aqueous foam.[3] It may be applied to other kinds of acoustic wave in different forms of turbid soft matter, such as biological tissues, pastes or concentrated emulsions. Now at Université Lyon 1 (ILM).

Vecteurs Singuliers des Theories des Champs Conformes Minimales

NASA Astrophysics Data System (ADS)

Benoit, Louis

En 1984 Belavin, Polyakov et Zamolodchikov revolutionnent la theorie des champs en explicitant une nouvelle gamme de theories, les theories quantiques des champs bidimensionnelles invariantes sous les transformations conformes. L'algebre des transformations conformes de l'espace-temps presente une caracteristique remarquable: en deux dimensions elle possede un nombre infini de generateurs. Cette propriete impose de telles conditions aux fonctions de correlations qu'il est possible de les evaluer sans aucune approximation. Les champs des theories conformes appartiennent a des representations de plus haut poids de l'algebre de Virasoro, une extension centrale de l'algebre conforme du plan. Ces representations sont etiquetees par h, le poids conforme de leur vecteur de plus haut poids, et par la charge centrale c, le facteur de l'extension centrale, commune a toutes les representations d'une meme theorie. Les theories conformes minimales sont constituees d'un nombre fini de representations. Parmi celles-ci se trouvent des theories unitaires dont les representation forment la serie discrete de l'algebre de Virasoro; leur poids h a la forme h_{p,q}(m)=[ (p(m+1) -qm)^2-1] (4m(m+1)), ou p,q et m sont des entiers positifs et p+q<= m+1. L'entier m parametrise la charge centrale: c(m)=1 -{6over m(m+1)} avec n>= 2. Ces representations possedent un sous-espace invariant engendre par deux sous-representations avec h_1=h_{p,q} + pq et h_2=h_{p,q} + (m-p)(m+1-q) dont chacun des vecteurs de plus haut poids portent le nom de vecteur singulier et sont notes respectivement |Psi _{p,q}> et |Psi_{m-p,m+1-q}>. . Les theories super-conformes sont une version super-symetrique des theories conformes. Leurs champs appartiennent a des representation de plus haut poids de l'algebre de Neveu-Schwarz, une des deux extensions super -symetriques de l'algebre de Virasoro. Les theories super -conformes minimales possedent la meme structure que les theories conformes minimales. Les representations

High sensitivity pH sensing on the BEOL of industrial FDSOI transistors

NASA Astrophysics Data System (ADS)

Rahhal, Lama; Ayele, Getenet Tesega; Monfray, Stéphane; Cloarec, Jean-Pierre; Fornacciari, Benjamin; Pardoux, Eric; Chevalier, Celine; Ecoffey, Serge; Drouin, Dominique; Morin, Pierre; Garnier, Philippe; Boeuf, Frederic; Souifi, Abdelkader

2017-08-01

In this work we demonstrate the use of Fully Depleted Silicon On Insulator (FDSOI) transistors as pH sensors with a 23 nm silicon nitride sensing layer built in the Back-End-Of-Line (BEOL). The back end process to deposit the sensing layer and fabricate the electrical structures needed for testing is detailed. A series of tests employing different pH buffer solutions has been performed on transistors of different geometries, controlled via the back gate. The main findings show a shift of the drain current (ID) as a function of the back gate voltage (VB) when different pH buffer solutions are probed in the range of pH 6 to pH 8. This shift is observed at VB voltages swept from 0 V to 3 V, demonstrating the sensor operation at low voltage. A high sensitivity of up to 250 mV/pH unit (more than 4-fold larger than Nernstian response) is observed on FDSOI MOS transistors of 0.06 μm gate length and 0.08 μm gate width. She is currently working as a Postdoctoral researcher at Institut des nanotechnologies de Lyon in collaboration with STMicroelectronics and Université de Sherbrook (Canada) working on ;Integration of ultra-low-power gas and pH sensors with advanced technologies;. Her research interest includes selection, machining, optimisation and electrical characterisation of the sensitive layer for a low power consumption gas sensor based on advanced MOS transistors.

Elemental analysis by IBA and NAA — A critical comparison

NASA Astrophysics Data System (ADS)

Watterson, J. I. W.

1988-12-01

In this review neutron activation analysis (NAA) and ion beam analysis (IBA) have been compared in the context of the entire field of analytical science using the discipline of scientometrics, as developed by Braun and Lyon. This perspective on the relative achievements of the two methods is modified by considering and comparing their particular attributes and characteristics, particularly in relation to their differing degree of maturity. This assessment shows that NAA, as the more mature method, is the most widely applied nuclear technique, but the special capabilities of IBA give it the ability to provide information about surface composition and elemental distribution that is unique, while it is still relatively immature and it is not yet possible to define its ultimate role with any confidence.

Immunocompetence analysis of the aquatic snail Lymnaea stagnalis exposed to urban wastewaters.

PubMed

Boisseaux, Paul; Noury, Patrice; Delorme, Nicolas; Perrier, Lucile; Thomas-Guyon, Helene; Garric, Jeanne

2018-04-02

Wastewater treatment plant effluents from urban area are a well-known source of chronic multiple micropollution to the downstream living organisms. In this study, ecologically relevant laboratory-bred freshwater gastropods, Lymnaea stagnalis, were exposed for 29 days to raw effluents of a wastewater treatment plant in Lyon area (France). A time-course analysis of individual markers of immunocompetence (hemocyte density and viability, hemocyte NADPH activity, phenol oxidase activity, and capacity of phagocytosis) has shown slight trends of inflammatory-like responses induced by the 100% effluents. So far, no short-term hazard for L. stagnalis can be revealed. However, over the long term, such environmental stress-stimulating immune responses could provoke deleterious life history trade-offs because the immune system is known to be highly energy-consuming.

Swift Heavy Ions in Matter

NASA Astrophysics Data System (ADS)

Rothard, Hermann; Severin, Daniel; Trautmann, Christina

2015-12-01

The present volume contains the proceedings of the Ninth International Symposium on Swift Heavy Ions in Matter (SHIM). This conference was held in Darmstadt, from 18 to 21 May 2015. SHIM is a triennial series, which started about 25 years ago by a joint initiative of CIRIL - Caen and GSI - Darmstadt, with the aim of promoting fundamental and applied interdisciplinary research in the field of high-energy, heavy-ion interaction processes with matter. SHIM was successively organized in Caen (1989), Bensheim (1992), Caen (1995), Berlin (1998), Catania (2002), Aschaffenburg (2005), Lyon (2008), and Kyoto (2012). The conference attracts scientists from many different fields using high-energy heavy ions delivered by large accelerator facilities and characterized by strong and short electronic excitations.

The effect of the blackout method on acquisition and generalization1

PubMed Central

Wildemann, Donald G.; Holland, James G.

1973-01-01

In discrimination training with the Lyons' blackout method, pecks to the negative stimulus are prevented by darkening the chamber each time the subject approaches the negative stimulus. Stimulus generalization along a stimulus dimension was measured after training with this method. For comparison, generalization was also measured after reinforced responding to the positive stimulus without discrimination training, and after discrimination training by extinction of pecks to the negative stimulus. The blackout procedure and the extinction of pecks to the negative stimulus both produced a peak shift in the generalization gradients. The results suggest that after discrimination training in which the positive and negative stimulus are on the same continuum, the blackout method produces extinction-like effects on generalization tests. PMID:16811655

Impact de la preparation des anodes crues et des conditions de cuisson sur la fissuration dans des anodes denses

NASA Astrophysics Data System (ADS)

Amrani, Salah

La fabrication de l'aluminium est realisee dans une cellule d'electrolyse, et cette operation utilise des anodes en carbone. L'evaluation de la qualite de ces anodes reste indispensable avant leur utilisation. La presence des fissures dans les anodes provoque une perturbation du procede l'electrolyse et une diminution de sa performance. Ce projet a ete entrepris pour determiner l'impact des differents parametres de procedes de fabrication des anodes sur la fissuration des anodes denses. Ces parametres incluent ceux de la fabrication des anodes crues, des proprietes des matieres premieres et de la cuisson. Une recherche bibliographique a ete effectuee sur tous les aspects de la fissuration des anodes en carbone pour compiler les travaux anterieurs. Une methodologie detaillee a ete mise au point pour faciliter le deroulement des travaux et atteindre les objectifs vises. La majorite de ce document est reservee pour la discussion des resultats obtenus au laboratoire de l'UQAC et au niveau industriel. Concernant les etudes realisees a l'UQAC, une partie des travaux experimentaux est reservee a la recherche des differents mecanismes de fissuration dans les anodes denses utilisees dans l'industrie d'aluminium. L'approche etait d'abord basee sur la caracterisation qualitative du mecanisme de la fissuration en surface et en profondeur. Puis, une caracterisation quantitative a ete realisee pour la determination de la distribution de la largeur de la fissure sur toute sa longueur, ainsi que le pourcentage de sa surface par rapport a la surface totale de l'echantillon. Cette etude a ete realisee par le biais de la technique d'analyse d'image utilisee pour caracteriser la fissuration d'un echantillon d'anode cuite. L'analyse surfacique et en profondeur de cet echantillon a permis de voir clairement la formation des fissures sur une grande partie de la surface analysee. L'autre partie des travaux est basee sur la caracterisation des defauts dans des echantillons d'anodes crues

Fiabilité des structures mécaniques adaptatives: effet de la panne des actionneurs ou des capteurs sur la stabilité

NASA Astrophysics Data System (ADS)

Fall, H.; Charon, W.; Kouta, R.

2002-12-01

Ces dernières décennies, des activités significatives dans le monde étaient dirigées autour du contrôle actif. Le but de ces recherches était essentiellement d'améliorer les performances, la fiabilité et la sécurité des systèmes. Notamment dans le cas des structures soumises à des vibrations aléatoires. D'importants travaux ont été consacré à l'utilisation des “matériaux intelligents” comme capteurs et actionneurs. Cette article propose l'analyse de la fiabilité des systèmes mécaniques en étudiant les pannes des actionneurs ou des capteurs. L'effet de ces pannes sur la stabilité et la performance du système y est démontré. Les méthodologies de conception y sont rappelées. Des exemples numériques sont fournis à travers le contrôle d'un panneau sous chargement dynamique pour illustrer la méthode proposée.

Le ciment brûle toujours

PubMed Central

Lebreton, T.; Fontaine, M.; Le Floch, R.

2017-01-01

Summary Les brûlures chimiques par ciment représentent une cause fréquente de corrosion cutanée en France. Elles nécessitent fréquemment un traitement chirurgical. Notre étude rétrospective concerne tous les patients admis pour une brûlure par ciment dans le service entre 2004 et 2016. Quarante-neuf patients âgés de 21 à 71 ans ont été pris en charge dans le centre des brûlés du Centre Hospitalier Saint Joseph Saint Luc à Lyon entre 2004 et 2016. La population concernée était majoritairement masculine, relativement jeune (44 ans en moyenne) et professionnellement active. Les brûlures survenaient principalement dans le cadre d’accidents domestiques (78%). Elles étaient profondes et atteignaient majoritairement les membres inférieurs, de façon bilatérale. La surface brûlée représentait 3% de la surface cutanée totale. Presque tous les patients (98%) ont nécessité une prise en charge chirurgicale pour excision et autogreffe de peau mince. Un seul patient a bénéficié d’une cicatrisation dirigée. Le délai moyen entre la brûlure et la chirurgie était de 13 jours et la durée moyenne d’hospitalisation de 8 jours. Sept patients ont nécessité une prise en charge en centre de rééducation à leur sortie du service. Cette étude confirme la sévérité des brûlures chimiques par ciment. Elle met également en avant l’impact que peut avoir ce type de brûlure en terme de retentissement socio-économique dans une population de patients majoritairement jeune et active. Elle insiste sur le fait que des mesures doivent être prises afin d’informer cette population rarement professionnelle sur les risques encourus lors du mésusage du ciment. La réglementation actuelle, classant le ciment comme irritant, ne prend pas en compte son caractère corrosif et devrait être amendée. PMID:28592929

Developpement des betons semi autoplacants a rheologie adaptee pour des infrastructures

NASA Astrophysics Data System (ADS)

Sotomayor Cruz, Cristian Daniel

Au cours des dernières décennies, les infrastructures canadiennes et québécoises comportent plusieurs structures en béton armé présentant des problèmes de durabilité dus aux conditions climatiques sévères, à la mauvaise conception des structures, à la qualité des matériaux, aux types des bétons choisis, aux systèmes de construction ou à l'existence d'événements incontrôlables. En ce qui concerne le choix du béton pour la construction des infrastructures, une vaste gamme de béton divisée en deux principaux types peut être utilisée: le béton conventionnel vibré (BCV) et le béton autoplaçant (BAP). Dans le cas d'un BCV, la consolidation inadéquate par vibration a été un problème récurrent, occasionnant des dommages structuraux. Ceci a conduit à une réduction de la durabilité et à une augmentation du coût d'entretien et de réparation des infrastructures. Rien que l'utilisation d'un BAP a des avantages tels que l'élimination de la vibration, la réduction des coûts de main d'oeuvre et l'amélioration de la qualité des structures, néanmoins, le coût initial d'un BAP par rapport à un BCV ne permet pas encore de généraliser son utilisation dans l'industrie de la construction. Ce mémoire présente la conception d'une nouvelle gamme de béton semi-autoplaçant pour la construction des infrastructures (BSAP-I) exigeant une vibration minimale. Il s'agit de trouver un équilibre optimal entre la rhéologie et le coût initial du nouveau béton pour conférer une bonne performance structurale et économique aux structures. Le programme expérimental établi a premièrement permis d'évaluer la faisabilité d'utilisation des BSAP-I pour la mise en place des piliers d'une infrastructure de pont à Sherbrooke. En plus, l'utilisation d'un plan d'expériences a permis l'évaluation de trois paramètres de formulation sur les propriétés des mélanges de BSAP-I à l'état frais et durci. Finalement, l'évaluation de la performance des

Paternité des articles et intérêts concurrents : une analyse des recommandations aux auteurs des journaux traitant de pratique pharmaceutique

PubMed Central

Courbon, Ève; Tanguay, Cynthia; Lebel, Denis; Bussières, Jean-François

2014-01-01

RÉSUMÉ Contexte : La présence d’auteurs honorifiques et fantômes ainsi que les intérêts concurrents représentent des difficultés bien documentées, liées à la publication d’articles scientifiques. Il existe des lignes directrices encadrant la rédaction et la publication de manuscrits scientifiques, notamment celles de l’International Committee of Medical Journal Editors (ICMJE). Objectifs : L’objectif principal de cette étude descriptive et transversale visait à recenser les instructions portant sur la paternité des articles et les intérêts concurrents provenant des recommandations aux auteurs des journaux traitant de pratique pharmaceutique. L’objectif secondaire visait à déterminer des mesures correctrices pour une paternité des articles plus transparente. Méthode : La recherche a débuté par l’identification des journaux traitant de pratique pharmaceutique. La consultation des instructions aux auteurs des journaux a permis ensuite de recenser les recommandations destinées à éviter les problèmes de paternité des articles et d’intérêts concurrents. Finalement, les membres de l’équipe de recherche se sont consultés afin de définir des mesures correctrices possibles à l’intention des chercheurs. Résultats : Des 232 journaux traitant de pharmacie, 33 ont été définis comme traitant de pratique pharmaceutique. Un total de 24 (73 %) journaux mentionnaient suivre la politique de l’ICMJE, 14 (42 %) demandaient aux auteurs de remplir un formulaire de déclaration d’intérêts concurrents au moment de la soumission de l’article, 17 (52 %) présentaient une définition de la qualité d’auteur et 5 (15 %) demandaient de détailler les contributions de chaque auteur. Une grille de 40 critères a été élaborée pour définir l’attribution du statut d’auteur. Conclusion : Moins de la moitié des journaux demandait aux auteurs de transmettre un formulaire de déclaration des intérêts concurrents au moment de la

Predicting global thunderstorm activity for sprite observations from the International Space Station

NASA Astrophysics Data System (ADS)

Yair, Y.; Mezuman, K.; Ziv, B.; Priente, M.; Glickman, M.; Takahashi, Y.; Inoue, T.

2012-04-01

The global rate of sprites occurring above thunderstorms, estimated from the ISUAL satellite data, is ~0.5 per minute (Chen et al., 2008). During the summer 2011, in the framework of the "Cosmic Shore" project, we conducted a concentrated attempt to image sprites from the ISS. The methodology for target selection was based on that developed for the space shuttle MEIDEX sprite campaign (Ziv et al., 2004). There are several types of convective systems generating thunderstorms which differ in their effectiveness for sprite production (Lyons et al., 2009), and so we had to evaluate the ability of the predicted storms to produce sprites. We used the Aviation Weather Center (http://aviationweather.gov) daily significant weather forecast maps (SIGWX) to select regions with high probability for convective storms and lightning such that they were within the camera filed-of-view as deduced from the ISS trajectory and distance to the limb. In order to enhance the chance for success, only storms with predicted "Frequent Cb" and cloud tops above 45 Kft (~14 km) were selected. Additionally, we targeted tropical storms and hurricanes over the oceans. The accuracy of the forecast method enabled obtaining the first-ever color images of sprites from space. We will report the observations showing various types of sprites in many different geographical locations, and correlated parent lightning properties derived from ELF and global and local lightning location networks. Chen, A. B., et al. (2008), Global distributions and occurrence rates of transient luminous events, J. Geophys. Res., 113,A08306, doi:10.1029/2008JA013101 Lyons, W. A., et al. (2009), The meteorological and electrical structure of TLE-producing convective storms. In: Betz et al. (eds.): Lighting: principles instruments and applications, Springer-Science + Business Media B.V.. Ziv, B., Y. Yair, K. Pressman and M. Fullekrug, (2004), Verification of the Aviation Center global forecasts of Mesoscale Convective Systems

Numerical Modeling of Wastewater Injection in the Denver Basin combined disposal zone in northeast Colorado

NASA Astrophysics Data System (ADS)

Brown, M. R. M.; Ge, S.; Sheehan, A. F.

2016-12-01

Previous studies have correlated seismicity with high rate injection at Underground Injection Control Class II wastewater disposal wells. In this study, we examine the impact of injection in the Denver Basin combined disposal zone that is used by numerous Class II wells. The disposal zone includes the Lyons Formation, a sandstone unit, and the Fountain Formation, an arkose unit just above the basement. Within a 30-km radius of the deep Class II injection well (NGL C4A) closest to the June 1, 2014 M3.2 Greeley earthquake, there are fifteen deep wastewater disposal wells injecting into the disposal zone and two shallow wastewater disposal wells injecting into the Lyons Formation only. One of the shallow wells is located at the same disposal facility as NGL-C4A and started injection in October 2004; the earliest deep injection in this region, at well NGL-C6, began in November 2007. The major episode of seismicity in the area started in November 2013. The timing of injection operation and seismicity occurrence raises several questions. Why did seismicity not begin in the area until nearly 10 years after the start of injection? Nine of the deep wastewater disposal wells began injection after the M3.2 earthquake on June 1, 2014; how does the large increase in the number of injection wells in the area change the pore-pressure in the disposal zone? How does the injection from the various wells interact? Does this increase the chances of induced seismicity? We conduct numerical modeling of 18 injection wells from 2004 to 2016 to explore these questions by better understanding the pore-pressure changes through time, pore-pressure changes in areas of induced earthquakes, and the interactions between injection wells. We include the asymmetry of the basin geometry in the model. We also use this case study to refine how well spacing and injection rate influences the occurrence of induced earthquakes.

[Lack of interest in general practice during the National Ranking Examination in 2005].

PubMed

Lanson, Yves

2006-03-01

The second national ranking test took place in 2005 in the same conditions as the year before. Analysis of the results permits us to assess whether the objectives of this reform have been met so far. Data crossing of the results provided by the national testing center allowed us to rank: 1) the appeal of specializations for each geographic subdivision, 2) the candidates by medical school, and 3) the appeal of each subdivision by candidate rank. 66% of the students were classified high enough to be able to choose any specialization. Trends observed from the first examination, in 2004, were confirmed, with the clear desirability of medical specializations and a certain lack of interest in occupational medicine and public health. All the surgery posts were filled, even though the number of posts had increased enormously since the first examination. After adjustment for the number of posts available, the specializations in decreasing order of popularity were: medical, surgical, pediatrics, anesthesiology, gynecology-obstetrics, general medicine, psychiatry, and biology. Approximately 1000 posts in general medicine were not filled. The medical schools whose students ranked highest were Paris Pitié, Paris V, Paris West, Lyon North, Grenoble, and Aix-Marseille. Some medical schools did less well than previously: Marseille very slightly and Angers substantially. Strasbourg, Nancy Amiens and Bobigny were at the bottom of the list. The cities most desired for internships were Paris, Toulouse, Lyon, and Aix-Marseille, while Brest, Nancy, Limoges and the West Indies were ranked lowest, although each was chosen by highly ranked candidate. Two thirds of the students were ranked high enough to allow them a free choice of specializations. All the specializations except public health and occupational medicine had very highly ranked students. Medical specializations are the most desired, but surgery remains highly demanded, despite a substantial increase in the number of posts. All

HELIOS: A new open-source radiative transfer code

NASA Astrophysics Data System (ADS)

Malik, Matej; Grosheintz, Luc; Lukas Grimm, Simon; Mendonça, João; Kitzmann, Daniel; Heng, Kevin

2015-12-01

I present the new open-source code HELIOS, developed to accurately describe radiative transfer in a wide variety of irradiated atmospheres. We employ a one-dimensional multi-wavelength two-stream approach with scattering. Written in Cuda C++, HELIOS uses the GPU’s potential of massive parallelization and is able to compute the TP-profile of an atmosphere in radiative equilibrium and the subsequent emission spectrum in a few minutes on a single computer (for 60 layers and 1000 wavelength bins).The required molecular opacities are obtained with the recently published code HELIOS-K [1], which calculates the line shapes from an input line list and resamples the numerous line-by-line data into a manageable k-distribution format. Based on simple equilibrium chemistry theory [2] we combine the k-distribution functions of the molecules H2O, CO2, CO & CH4 to generate a k-table, which we then employ in HELIOS.I present our results of the following: (i) Various numerical tests, e.g. isothermal vs. non-isothermal treatment of layers. (ii) Comparison of iteratively determined TP-profiles with their analytical parametric prescriptions [3] and of the corresponding spectra. (iii) Benchmarks of TP-profiles & spectra for various elemental abundances. (iv) Benchmarks of averaged TP-profiles & spectra for the exoplanets GJ1214b, HD189733b & HD209458b. (v) Comparison with secondary eclipse data for HD189733b, XO-1b & Corot-2b.HELIOS is being developed, together with the dynamical core THOR and the chemistry solver VULCAN, in the group of Kevin Heng at the University of Bern as part of the Exoclimes Simulation Platform (ESP) [4], which is an open-source project aimed to provide community tools to model exoplanetary atmospheres.-----------------------------[1] Grimm & Heng 2015, ArXiv, 1503.03806[2] Heng, Lyons & Tsai, Arxiv, 1506.05501Heng & Lyons, ArXiv, 1507.01944[3] e.g. Heng, Mendonca & Lee, 2014, ApJS, 215, 4H[4] exoclime.net

Brace technology thematic series - The Sforzesco and Sibilla braces, and the SPoRT (Symmetric, Patient oriented, Rigid, Three-dimensional, active) concept

PubMed Central

2011-01-01

Background Bracing is an effective strategy for scoliosis treatment, but there is no consensus on the best type of brace, nor on the way in which it should act on the spine to achieve good correction. The aim of this paper is to present the family of SPoRT (Symmetric, Patient-oriented, Rigid, Three-dimensional, active) braces: Sforzesco (the first introduced), Sibilla and Lapadula. Methods The Sforzesco brace was developed following specific principles of correction. Due to its overall symmetry, the brace provides space over pathological depressions and pushes over elevations. Correction is reached through construction of the envelope, pushes, escapes, stops, and drivers. The real novelty is the drivers, introduced for the first time with the Sforzesco brace; they allow to achieve the main action of the brace: a three-dimensional elongation pushing the spine in a down-up direction. Brace prescription is made plane by plane: frontal (on the "slopes", another novelty of this concept, i.e. the laterally flexed sections of the spine), horizontal, and sagittal. The brace is built modelling the trunk shape obtained either by a plaster cast mould or by CAD-CAM construction. Brace checking is essential, since SPoRT braces are adjustable and customisable according to each individual curve pattern. Treatment time and duration is individually tailored (18-23 hours per day until Risser 3, then gradual reduction). SEAS (Scientific Exercises Approach to Scoliosis) exercises are a key factor to achieve success. Results The Sforzesco brace has shown to be more effective than the Lyon brace (matched case/control), equally effective as the Risser plaster cast (prospective cohort with retrospective controls), more effective than the Risser cast + Lyon brace in treating curves over 45 degrees Cobb (prospective cohort), and is able to improve aesthetic appearance (prospective cohort). Conclusions The SPoRT concept of bracing (three-dimensional elongation pushing in a down-up direction

Electrocardiographic Impact of Myocardial Diffuse Fibrosis and Scar: MESA (Multi-Ethnic Study of Atherosclerosis)

PubMed Central

Inoue, Yuko Y.; Ambale-Venkatesh, Bharath; Mewton, Nathan; Volpe, Gustavo J.; Ohyama, Yoshiaki; Sharma, Ravi K.; Wu, Colin O.; Liu, Chia-Ying; Bluemke, David A.; Soliman, Elsayed Z.; Lima, João A. C.

2017-01-01

Purpose To examine the associations of myocardial diffuse fibrosis and scar with surface electrocardiographic (ECG) parameters in individuals free of prior coronary heart disease in four different ethnicities. Materials and Methods This prospective cross-sectional study was approved by the institutional review boards, and all participants gave informed consent. A total of 1669 participants in the Multi-Ethnic Study of Atherosclerosis, or MESA, who were free of prior myocardial infarction underwent both ECG and cardiac magnetic resonance imaging. In individuals without a late gadolinium enhancement–defined myocardial scar (n = 1131), T1 mapping was used to assess left ventricular (LV) interstitial diffuse fibrosis. The associations of LV diffuse fibrosis or myocardial scar with ECG parameters (QRS voltage, QRS duration, and corrected QT interval [QTc]) were evaluated by using multivariable regression analyses adjusted for demographic data, risk factors for scar, LV end-diastolic volume, and LV mass. Results The mean age of the 1669 participants was 67.4 years ± 8.7 (standard deviation); 49.8% were women. Lower postcontrast T1 time at 12 minutes was significantly associated with lower QRS Sokolow-Lyon voltage (β = 15.1 µV/10 msec, P = .004), lower QRS Cornell voltage (β = 9.2 µV/10 msec, P = .031), and shorter QRS duration (β = 0.16 msec/10 msec, P = .049). Greater extracellular volume (ECV) fraction was also significantly associated with lower QRS Sokolow-Lyon voltage (β = −35.2 µV/1% ECV increase, P < .001) and Cornell voltage (β = −23.7 µV/1% ECV increase, P < .001), independent of LV structural indexes. In contrast, the presence of LV scar (n = 106) was associated with longer QTc (β = 4.3 msec, P = .031). Conclusion In older adults without prior coronary heart disease, underlying greater LV diffuse fibrosis is associated with lower QRS voltage and shorter QRS duration at surface ECG, whereas clinically unrecognized myocardial scar is associated

Delayed methotrexate elimination: Incidence, interaction with antacid drugs, and clinical consequences?

PubMed

Ranchon, Florence; Vantard, Nicolas; Henin, Emilie; Bachy, Emmanuel; Sarkozy, Clémentine; Karlin, Lionel; Bouafia-Sauvy, Fadhela; Gouraud, Aurore; Schwiertz, Verane; Bourbon, Estelle; Baudouin, Amandine; Caffin, Anne Gaelle; Vial, Thierry; Salles, Gilles; Rioufol, Catherine

2018-04-01

The aim of this retrospective cohort study was to investigate the incidence of delayed methotrexate elimination in patients treated with high-dose methotrexate (≥1 g/m 2 ) for haematological malignancy and to identify the impact of interacting drugs, especially proton-pump inhibitors (PPIs) and ranitidine. All patients treated with high-dose methotrexate over a 6 year period in the haematology department of the Lyon Sud University Hospital (Hospices Civils de Lyon, France) were included. Potential risk factors for delayed methotrexate elimination were tested in a generalized linear model by univariate analysis: patient age, gender, methotrexate dose, administration of PPI or ranitidine, and concomitant nephrotoxic drugs. A total of 412 cycles of methotrexate were administered to 179 patients. Proton-pump inhibitors were co-administered with methotrexate in 127 cycles and ranitidine in 192 cycles. Ninety-three cycles included no antacid drugs. A total of 918 plasma methotrexate assays were performed. Methotrexate concentrations were checked at 24 hours in 92% of cycles. Delayed methotrexate elimination was observed in 20.9% of cycles. A total of 63 cycles with delayed methotrexate elimination were only identified on plasma methotrexate measures at 72 hours: ie, plasma methotrexate was in the normal range at 24 and 48 hour post injection. Use of PPI/ranitidine or no antacid drugs did not increase risk of delayed elimination, with respectively delayed methotrexate elimination in 20.5%, 21.9%, and 19.4% of cycles (P = .89). Impaired baseline creatinine clearance showed significant association in univariate analysis. Fifteen patients showed grade 1 acute kidney injury, 1 grade 2, 2 grade 3, and none grade 4. For half of these cases, delayed methotrexate elimination was observed and the 2 grade 3 events appeared in patients treated with PPIs. This retrospective study suggests that there is no association between concomitant use of proton-pump inhibitors

Caracterisation des melanges developpes pour le moulage basse pression des poudres metalliques (LPIM) =

NASA Astrophysics Data System (ADS)

Fareh, Fouad

Le moulage par injection basse pression des poudres metalliques est une technique de fabrication qui permet de fabriquer des pieces possedant la complexite des pieces coulees mais avec les proprietes mecaniques des pieces corroyees. Cependant, l'optimisation des etapes de deliantage et de frittage a ete jusqu'a maintenant effectuee a l'aide de melange pour lesquels la moulabilite optimale n'a pas encore ete demontree. Ainsi, la comprehension des proprietes rheologiques et de la segregation des melanges est tres limitee et cela presente le point faible du processus de LPIM. L'objectif de ce projet de recherche etait de caracteriser l'influence des liants sur le comportement rheologique des melanges en mesurant la viscosite et la segregation des melanges faible viscosite utilises dans le procede LPIM. Afin d'atteindre cet objectif, des essais rheologiques et thermogravimetriques ont ete conduits sur 12 melanges. Ces melanges ont ete prepares a base de poudre d'Inconel 718 de forme spherique (chargement solide constant a 60%) et de cires, d'agents surfactants ou epaississants. Les essais rheologiques ont ete utilises entre autre pour calculer l'indice d'injectabilite ?STV des melanges, tandis que les essais thermogravimetriques ont permis d'evaluer precisement la segregation des poudres dans les melanges. Il a ete demontre que les trois (3) melanges contenant de la cire de paraffine et de l'acide stearique presentent des indices alpha STV plus eleves qui sont avantageux pour le moulage par injection des poudres metalliques (MIM), mais segregent beaucoup trop pour que la piece fabriquee produise de bonnes caracteristiques mecaniques. A l'oppose, le melange contenant de la cire de paraffine et de l'ethylene-vinyle acetate ainsi que le melange contenant seulement de la cire de carnauba segregent peu voire pas du tout, mais possedent de tres faibles indices alphaSTV : ils sont donc difficilement injectables. Le meilleur compromis semble donc etre les melanges contenant de

La participation des enfants et des adolescents à la boxe

PubMed Central

Purcell, Laura K; LeBlanc, Claire MA

2012-01-01

RÉSUMÉ Des milliers de garçons et de filles de moins de 19 ans font de la boxe en Amérique du Nord. Même si la boxe comporte des avantages pour ceux qui y participent, y compris l’exercice, l’autodiscipline et la confiance en soi, le sport lui-même favorise et récompense des coups délibérés à la tête et au visage. Les personnes qui font de la boxe risquent de subir des blessures à la tête, au visage et au cou, y compris des traumatismes neurologiques chroniques et même fatals. Les commotions cérébrales sont l’une des principales blessures causées par la boxe. En raison du risque de blessures crâniennes et faciales, la Société canadienne de pédiatrie et l’American Academy of Pediatrics s’opposent vigoureusement à la boxe comme activité sportive pour les enfants et les adolescents. Ces organismes recommandent que les médecins s’élèvent contre la boxe auprès des jeunes et les encouragent à participer à d’autres activités dans lesquelles les coups intentionnels à la tête ne constituent pas un élément essentiel du sport.

Correlations among densities of stream fishes in the upper Neosho River, with focus on the federally threatened Neosho madtom Noturus placidus

USGS Publications Warehouse

Tiemann, Jeremy S.; Gillette, David P.; Wildhaber, Mark L.; Edds, David R.

2004-01-01

We sampled fishes monthly from November 2000 to October 2001 at four gravel bar sites along a 34-km stretch of the upper Neosho River in Lyon County, Kansas. We assessed the potential for interspecific competition among stream fishes, with focus on the federally threatened Neosho madtom, Noturus placidus, by using Pearson's correlation analysis with sequential Bonferroni correction of alpha to examine relationships among fish densities. Of the 19 fish species analyzed, there were six significant positive and no significant negative correlations. Abundance of N. placidusdid not vary significantly with total abundance of fishes or with abundance of any of these potential competitors. The lack of significant negative correlations at these sites at this time might reflect an assemblage in equilibrium or one controlled abiotically rather than by ongoing active competition.

KSC-2010-1267

NASA Image and Video Library

2010-01-15

CAPE CANAVERAL, Fla. - Jim Lyon, biological science technician with the Merritt Island National Wildlife Refuge, carries a green sea turtle toward the waterline of the Banana River at NASA's Kennedy Space Center in Florida. A recent cold snap left this turtle and nearly 2,000 others "stunned" and in need of help. Many of the turtles were rescued from the Mosquito Lagoon, with others coming from the Indian River Lagoon and Cocoa Beach. Biologists, environmentalists, wildlife experts and other volunteers joined forces with a massive rescue effort at the Merritt Island National Wildlife Refuge, where the turtles were identified, examined and transported to rehabilitation facilities throughout Florida and South Georgia. The animals stayed at these facilities until local waters warmed up to safe temperatures. Photo credit: NASA/Troy Cryder

Assessment of the contribution of sewer deposits to suspended solids loads in combined sewer systems during rain events.

PubMed

Hannouche, A; Chebbo, G; Joannis, C

2014-04-01

Within the French observatories network SOERE "URBIS," databases of continuous turbidity measurements accumulating hundreds of events and many dry weather days are available for two sites with different features (Clichy in Paris and Ecully in Lyon). These measurements, converted into total suspended solids (TSS) concentration using TSS-turbidity relationships and combined with a model of runoff event mean concentration, enable the assessment of the contribution of sewer deposits to wet weather TSS loads observed at the outlet of the two watersheds. Results show that the contribution of sewer deposits to wet weather suspended solid's discharges is important but variable (between 20 and 80 % of the mass at the outlet depending on the event), including a site allegedly free of (coarse) sewer deposits. The uncertainties associated to these results are assessed too.

Membrane fluidization by alcohols inhibits DesK-DesR signalling in Bacillus subtilis.

PubMed

Vaňousová, Kateřina; Beranová, Jana; Fišer, Radovan; Jemioła-Rzemińska, Malgorzata; Matyska Lišková, Petra; Cybulski, Larisa; Strzałka, Kazimierz; Konopásek, Ivo

2018-03-01

After cold shock, the Bacillus subtilis desaturase Des introduces double bonds into the fatty acids of existing membrane phospholipids. The synthesis of Des is regulated exclusively by the two-component system DesK/DesR; DesK serves as a sensor of the state of the membrane and triggers Des synthesis after a decrease in membrane fluidity. The aim of our work is to investigate the biophysical changes in the membrane that are able to affect the DesK signalling state. Using linear alcohols (ethanol, propanol, butanol, hexanol, octanol) and benzyl alcohol, we were able to suppress Des synthesis after a temperature downshift. The changes in the biophysical properties of the membrane caused by alcohol addition were followed using membrane fluorescent probes and differential scanning calorimetry. We found that the membrane fluidization induced by alcohols was reflected in an increased hydration at the lipid-water interface. This is associated with a decrease in DesK activity. The addition of alcohol mimics a temperature increase, which can be measured isothermically by fluorescence anisotropy. The effect of alcohols on the membrane periphery is in line with the concept of the mechanism by which two hydrophilic motifs located at opposite ends of the transmembrane region of DesK, which work as a molecular caliper, sense temperature-dependent variations in membrane properties. Copyright © 2017 Elsevier B.V. All rights reserved.

Comparison of LFM-test particle simulations and radial diffusion models of radiation belt electron injection into the slot region

NASA Astrophysics Data System (ADS)

Chu, F.; Hudson, M.; Kress, B.

2008-12-01

The physics-based Lyon-Fedder-Mobarry (LFM) code simulates Earth's magnetospheric topology and dynamics by solving the equations of ideal MHD using input solar wind parameters at the upstream boundary. Comparison with electron phase space density evolution during storms using a radial diffusion code, as well as spacecraft measurements where available, will tell us when diffusion is insufficiently accurate for radiation belt simulation, for example, during CME-shock injection events like March 24, 1991, which occurred on MeV electron drift time scales of minutes (Li et al., 1993). The 2004 July and 2004 November storms, comparable in depth of penetration into the slot region to the Halloween 2003 storm, have been modeled with both approaches. The November 8, 2004 storm was preceded by a Storm Sudden Commencement produced by a CME-shock followed by minimum Dst = -373 nT, while the July 23 to July 28 storm interval had milder consecutive drops in Dst, corresponding to multiple CME shocks and southward IMF Bz turnings. We have run the November and July storms with LFM using ACE data as upstream input, running the July storm with lower temporal resolution over a longer time interval. The November storm was different because the SCC shock was unusually intense, therefore the possibility of drift time scale acceleration by the associated magnetosonic impulse produced by the shock exists, as in March 1991 and also Halloween 2003 events (Kress et al., 2007). It can then take a short time (minutes) for electrons to be transported to low L shell while conserving their first invariant, resulting in a peak in energy and phase space density in the slot region. Radial diffusion suffices for some storm periods like the July 2004 sequence of three storms, while the guiding center test particle simulation in MHD fields is necessary to describe prompt injections which occur faster than diffusive time scales, for which November 2004 is a likely candidate. Earlier examples have been

Etude du processus de changement vecu par des familles ayant decide d'adopter volontairement des comportements d'attenuation des changements climatiques

NASA Astrophysics Data System (ADS)

Leger, Michel T.

Les activites humaines energivores telles l'utilisation intensive de l'automobile, la surconsommation de biens et l'usage excessif d'electricite contribuent aux changements climatiques et autres problemes environnementaux. Bien que plusieurs recherches rapportent que l'etre humain est de plus en plus conscient de ses impacts sur le climat de la planete, ces memes recherches indiquent qu'en general, les gens continuent a se comporter de facon non ecologique. Que ce soit a l'ecole ou dans la communaute, plusieurs chercheurs en education relative a l'environnement estiment qu'une personne bien intentionnee est capable d'adopter des comportements plus respectueux de l'environnement. Le but de cette these etait de comprendre le processus d'integration de comportements d'attenuation des changements climatiques dans des familles. A cette fin, nous nous sommes fixe deux objectifs : 1) decrire les competences et les procedes qui favorisent l'adoption de comportements d'attenuation des changements climatiques dans des familles et 2) decrire les facteurs et les dynamiques familiales qui facilitent et limitent l'adoption de comportements d'attenuation des changements climatiques dans des familles. Des familles ont ete invitees a essayer des comportements personnels et collectifs d'attenuation des changements climatiques de sorte a integrer des modes de vie plus ecologiques. Sur une periode de huit mois, nous avons suivi leur experience de changement afin de mieux comprendre comment se produit le processus de changement dans des familles qui decident volontairement d'adopter des comportements d'attenuation des changements climatiques. Apres leur avoir fourni quelques connaissances de base sur les changements climatiques, nous avons observe le vecu de changement des familles durant huit mois d'essais a l'aide de journaux reflexifs, d'entretiens d'explicitation et du journal du chercheur. La these comporte trois articles scientifiques. Dans le premier article, nous presentons une

Des ballons pour demain

NASA Astrophysics Data System (ADS)

Régipa, R.

A partir d'une théorie sur la détermination des formes et des contraintes globales d'un ballon de révolution, ou s'en rapprochant, une nouvelle famille de ballons a été définie. Les ballons actuels, dits de ``forme naturelle'', sont calculés en général pour une tension circonférencielle nulle. Ainsi, pour une mission donnée, la tension longitudinale et la forme de l'enveloppe sont strictement imposées. Les ballons de la nouvelle génération sont globalement cylindriques et leurs pôles sont réunis par un câble axial, chargé de transmettre une partie des efforts depuis le crochet (pôle inférieur), directement au pôle supérieur. De plus, la zone latérale cylindrique est soumise à un faible champ de tensions circonférencielles. Ainsi, deux paramètres permettent de faire évoluer la distribution des tensions et la forme de l'enveloppe: - la tension du câble de liaison entre pôles (ou la longueur de ce câble) - la tension circonférencielle moyenne désirée (ou le rayon du ballon). On peut donc calculer et réaliser: - soit des ballons de forme adaptée, comme les ballons à fond plat pour le bon fonctionnement des montgolfières infrarouge (projet MIR); - soit des ballons optimisés pour une bonne répartition des contraintes et une meilleure utilisation des matériaux d'enveloppe, pour l'ensemble des programmes stratosphériques. Il s'ensuit une économie sensible des coûts de fabrication, une fiabilité accrue du fonctionnement de ces ballons et une rendement opérationnel bien supérieur, permettant entre autres, d'envisager des vols à très haute altitude en matériaux très légers.

Diethylstilbestrol (DES) and Cancer

MedlinePlus

... Genetics Services Directory Cancer Prevention Overview Research Diethylstilbestrol (DES) and Cancer On This Page What is DES? ... outlined in the table below. Fertility Problems in DES Daughters ( 7 ) Fertility Complication Hazard Ratio Percent Cumulative ...

Maladie des vibrations

PubMed Central

Shen, Shixin (Cindy); House, Ronald A.

2017-01-01

Résumé Objectif Permettre aux médecins de famille de comprendre l’épidémiologie, la pathogenèse, les symptômes, le diagnostic et la prise en charge de la maladie des vibrations, une maladie professionnelle importante et courante au Canada. Sources d’information Une recherche a été effectuée sur MEDLINE afin de relever les recherches et comptes rendus portant sur la maladie des vibrations. Une recherche a été effectuée sur Google dans le but d’obtenir la littérature grise qui convient au contexte canadien. D’autres références ont été tirées des articles relevés. Message principal La maladie des vibrations est une maladie professionnelle répandue touchant les travailleurs de diverses industries qui utilisent des outils vibrants. La maladie est cependant sous-diagnostiquée au Canada. Elle compte 3 éléments : vasculaire, sous la forme d’un phénomène de Raynaud secondaire; neurosensoriel; et musculosquelettique. Aux stades les plus avancés, la maladie des vibrations entraîne une invalidité importante et une piètre qualité de vie. Son diagnostic exige une anamnèse minutieuse, en particulier des antécédents professionnels, un examen physique, des analyses de laboratoire afin d’éliminer les autres diagnostics, et la recommandation en médecine du travail aux fins d’investigations plus poussées. La prise en charge consiste à réduire l’exposition aux vibrations, éviter les températures froides, abandonner le tabac et administrer des médicaments. Conclusion Pour assurer un diagnostic rapide de la maladie des vibrations et améliorer le pronostic et la qualité de vie, les médecins de famille devraient connaître cette maladie professionnelle courante, et pouvoir obtenir les détails pertinents durant l’anamnèse, recommander les patients aux cliniques de médecine du travail et débuter les demandes d’indemnisation de manière appropriée. PMID:28292812

Etat des lieux des soins de premier recours des malades mentaux à Antananarivo : étude rétrospective

PubMed Central

Bakohariliva, Hasina Andrianarivony; Rafehivola, Imisanavalona Hanitrinihaja; Raobelle, Evah Norotiana; Raharivelo, Adeline; Rajaonarison, Bertille Hortense

2018-01-01

Résumé Religion et guérisseurs traditionnels occupent encore une place prépondérante dans la prise en charge des maladies mentales à Madagascar. Ainsi, nous nous sommes fixés comme objectif d'établir un état des lieux sur les soins de premier recours des malades mentaux. Nous avons mené une étude rétrospective descriptive s'étalant sur une période de 16 mois allant de janvier 2014 en avril 2015 au sein du service de psychiatrie du CHU de Befelatanana à Antananarivo. La prévalence des psychoses était de 25%. Le genre féminin (53%), l'ethnie merina (77%), les étudiants (45%), le niveau d'étude secondaire (40%), les célibataires (72%), la religion protestante (45%), ainsi que le niveau socio-économique moyen (57,5%) étaient prédominants. Dans les paramètres cliniques, le mode de début brutal (52%), le premier recours à la religion (40%), la présence d'antécédents des cas similaire (90%), étaient majoritaires. La schizophrénie était la pathologie la plus rencontrée dans la moitié des cas. Le délai d'amélioration en cas de traitement religieux et traditionnels était dans la moitié des cas de plus de 10 jours d'hospitalisation. Les patients ayant reçu une prise en charge psychiatrique en premier recours, étaient améliorés dans 75 % cas en moins de 10jours. Le retard du recours aux soins psychiatriques est une réalité à Madagascar qui aggrave le pronostic des psychoses. PMID:29632623

Litigation involving DES.

PubMed

Rheingold, P D

1976-01-01

Focus is on the diethylstilbestrol (DES) litigation which has resulted from the 1971 discovery that this synthetic estrogen can cause cancer in the daughters of women who used the drug during pregnancy in an effort to prevent threatened abortion. Possibly 100 suits are pending at this time in which DES daughters claim injuries. In most of these vaginal or cervical cancer has appeared -- with or without a hysterectomy having been performed. Several women died from cancer. The fact that the use of DES occurred many years ago is the legal hurdle most troublesome to lawyers. The average women coming to a lawyer's office today has a mother who used some form of DES, perhaps in 1955. Few drugstores have records today of the prescriptions which they filled 20 years ago. It has been estimated that over the 1950-1970 period more than 200 different companies manufactured or "tabletized" under their own name DES plus a variety of similar synthetic estrogens promoted for the prevention of threatened abortion. A further hurdle caused by the passage of time is that even the records of the physicians are frequently lost. A final problem created by the age of the cases is statute of limitations. If the actual manufacturer of the DES cannot be identified, this is generally the end of the lawyer's interest in the case. The chance of the plaintiff winning may be increased if the action against all the manufacturers is a class action. Most of the pending DES suits are against the manufacturer and not against the doctor. Thus far no DES case has been tried to completion. Several have been settled by the manufacturers on the eve of the trial, generally for less than the full sum that a cancer victim would expect to receive.

Médecine des voyages

PubMed Central

Aw, Brian; Boraston, Suni; Botten, David; Cherniwchan, Darin; Fazal, Hyder; Kelton, Timothy; Libman, Michael; Saldanha, Colin; Scappatura, Philip; Stowe, Brian

2014-01-01

Résumé Objectif Définir la pratique de la médecine des voyages, présenter les éléments fondamentaux d’une consultation complète préalable aux voyages à des voyageurs internationaux et aider à identifier les patients qu’il vaudrait mieux envoyer en consultation auprès de professionnels de la médecine des voyages. Sources des données Les lignes directrices et les recommandations sur la médecine des voyages et les maladies liées aux voyages publiées par les autorités sanitaires nationales et internationales ont fait l’objet d’un examen. Une recension des ouvrages connexes dans MEDLINE et EMBASE a aussi été effectuée. Message principal La médecine des voyages est une spécialité très dynamique qui se concentre sur les soins préventifs avant un voyage. Une évaluation exhaustive du risque pour chaque voyageur est essentielle pour mesurer avec exactitude les risques particuliers au voyageur, à son itinéraire et à sa destination et pour offrir des conseils sur les interventions les plus appropriées en gestion du risque afin de promouvoir la santé et prévenir les problèmes médicaux indésirables durant le voyage. Des vaccins peuvent aussi être nécessaires et doivent être personnalisés en fonction des antécédents d’immunisation du voyageur, de son itinéraire et du temps qu’il reste avant son départ. Conclusion La santé et la sécurité d’un voyageur dépendent du degré d’expertise du médecin qui offre le counseling préalable à son voyage et les vaccins, au besoin. On recommande à ceux qui donnent des conseils aux voyageurs d’être conscients de l’ampleur de cette responsabilité et de demander si possible une consultation auprès de professionnels de la médecine des voyages pour tous les voyageurs à risque élevé.

Determination des Parametres Atmospheriques des Etoiles Naines Blanches de Type DB

NASA Astrophysics Data System (ADS)

Beauchamp, Alain

1995-01-01

Les etoiles naines blanches dont les spectres visibles sont domines par des raies fortes d'helium neutre sont subdivisees en trois classes, DB (raies d'helium neutre seulement), DBA (raies d'helium neutre et d'hydrogene) et DBZ (raies d'helium neutre et d'elements lourds). Nous analysons trois echantillons de spectres observes de ces types de naines blanches. Les echantillons consistent, respectivement, de 48 spectres dans le domaine du visible (3700-5100 A). 24 dans l'ultraviolet (1200-3100 A) et quatre dans la partie rouge du visible (5100-6900) A). Parmi les objets de l'echantillon visible, nous identifions quatre nouvelles DBA, ainsi que deux nouvelles DBZ, auparavant classees DB. L'analyse nous permet de determiner spectroscopiquement les parametres atmospheriques, soit la temperature effective, la gravite de surface, ainsi que l'abondance relative de l'hydrogene, N(H)/N(He), dans le cas des DBA. Pour les objets plus chauds que ~15,000 K, la gravite de surface determinee est fiable, et nous obtenons les masses stellaires avec une relation masse -rayon theorique. Les exigences propres a l'analyse de ces objets ont requis d'importantes ameliorations dans la modelisation de leurs atmospheres et distributions de flux de radiation emis par ces derniers. Nous avons inclus dans les modeles d'atmospheres, pour la premiere fois a notre connaissance, les effets dus a la molecule He_sp{2 }{+}, ainsi que l'equation d'etat de Hummer et Mihalas (1988), qui tient compte des perturbations entre particules dans le calcul des populations des differents niveaux atomiques. Nous traitons la convection dans le cadre de la theorie de la longueur de melange. Trois grilles de modeles d'atmospheres a l'ETL (equilibre thermodynamique local) ont ete produites, pour un ensemble de temperatures effectives, gravites de surface et abondances d'hydrogene couvrant les proprietes des etoiles de nos echantillons; elles sont caracterisees par differentes parametrisations appelees, respectivement

KSC-2013-2217

NASA Image and Video Library

2013-04-27

CAPE CANAVERAL, Fla. – At NASA’s Kennedy Space Center Visitor Complex in Florida, previous winners of the National Space Club Florid Committee's Dr. Kurt H. Debus Award pose with this year's honoree, center director Bob Cabana. From the left, are: Rick Abramson, Dick Beagley, Dick Lyon, Patty Stratton, Lyle Holloway, Lee Solid, Cabana, Dr. Maxwell King, Bob Sieck, Jerry Jamison, Roy Tharpe and Ernie Briel. A former U.S. Marine Corps aviator and NASA astronaut, Cabana was honored at the gala Debus Award Dinner. Named for the spaceport’s first director, the Debus Award was created to recognize significant achievements and contributions made in Florida to American aerospace efforts. The Debus Award was created by the space club's Florida committee to recognize significant achievements and contributions made in Florida to American aerospace efforts. Photo credit: NASA/Jim Grossmann

[The unicorn and the unicorn horn among apothecaries and physicians].

PubMed

Fischer, Louis-Paul; Cossu Ferra Fischer, Véronique

2011-01-01

In the 4th century A.D. the first unicorn was shown as a little horse with a twisted horn and was completely different from the Oriental one described by Marco Polo. The new unicorn appeared during the 4th century A.D. in Alexandria. This animal enamoured of purity was used as a Christian symbol of purity and sacrifice and adornment of churches like in Lyons in the 13th century. In the 15th & 17th centuries the unicorn was found again in famous tapestries like La Dame B la Licorne as it meant courage, speed and purity. Since the 6th century the powder of unicorn horn was used as a medicine or a drug against poisoning. Depictions of unicorn can be found in chemist's signs, engravings or paintings until the 19th century.

Jean-Louis Brachet (1789-1858). A forgotten contributor to early 19th century neurology.

PubMed

Walusinski, O

2015-10-01

Specialists of the history of hysteria know the name of Jean-Louis Brachet (1789-1858), but few realise the influence of this physician and surgeon from Lyon, a city in the southeastern part of France. Not only a clinician, he was also a neurophysiology researcher in the early 19th century. Along with his descriptions of meningoencephalitis, including hydrocephalus and meningoencephalitis, he elucidated the functioning of the vegetative nervous system and described its activity during emotional states. He also helped describe the different forms of epilepsy and sought to understand their aetiologies, working at the same time as the better-known Louis-Florentin Calmeil (1798-1895). We present a biography of this forgotten physician, a prolific writer, keen clinical observer and staunch devotee of a rigorous scientific approach. Copyright © 2015 Elsevier Masson SAS. All rights reserved.

NUREBASE: database of nuclear hormone receptors.

PubMed

Duarte, Jorge; Perrière, Guy; Laudet, Vincent; Robinson-Rechavi, Marc

2002-01-01

Nuclear hormone receptors are an abundant class of ligand activated transcriptional regulators, found in varying numbers in all animals. Based on our experience of managing the official nomenclature of nuclear receptors, we have developed NUREBASE, a database containing protein and DNA sequences, reviewed protein alignments and phylogenies, taxonomy and annotations for all nuclear receptors. The reviewed NUREBASE is completed by NUREBASE_DAILY, automatically updated every 24 h. Both databases are organized under a client/server architecture, with a client written in Java which runs on any platform. This client, named FamFetch, integrates a graphical interface allowing selection of families, and manipulation of phylogenies and alignments. NUREBASE sequence data is also accessible through a World Wide Web server, allowing complex queries. All information on accessing and installing NUREBASE may be found at http://www.ens-lyon.fr/LBMC/laudet/nurebase.html.

[Inter-laboratory reproducibility of pulsed-field electrophoresis for the study of 12 types of Pseudomonas aeruginosa].

PubMed

Foissaud, V; Puyhardy, J M; Chapalain, J C; Salord, H; Depina, J J; Morillon, M; Nicolas, P; Perrier-Gros-Claude, J D

1999-12-01

The increasing hospital-to-hospital transmission of multiple drug-resistant bacteria is a major concern for bacteriology laboratories involved in nosocomial infection control. The interlaboratory reproducibility of pulsed-field gel electrophoresis (PFGE) for Pseudomonas aeruginosa typing was evaluated by asking four hospital laboratories (two in Lyon, one in Brest, and one in Marseille) to study 11 P. aeruginosa isolates, some of which were epidemiologically related, and the reference strain ATCC 27853. Two laboratories used the Genepath system, one the Chef DR II, system, and one the Chef Mapper system, Bio-Rad, restriction/Spe I. Profiles were read visually and by computerized comparison of restriction band molecular weights (Taxotron, software, PAD Grimont, Pasteur Institute, Paris, France). These two methods led to similar epidemiological conclusions. However, centralization of the data showed poor center-to-center reproducibility due to inadequate standardization of the procedure.

[School reinsertion of children treated for tumors of the brain: experience of the Léon-Bérard center].

PubMed

Frappaz, D; Marec-Bérard, P; Schell, M; Bouffet, E; Rougier, D; Blanchard, P; Roussin, G; Liger, A; Bergeron, C; Philip, T; Zucchinelli, V

2001-12-01

School integration of children with brain tumor is part of the quality of their life. It may also become a nightmare both for the child and for the teacher when no recommendation has been addressed to the latter. In France, official recommendations allow the meeting and information exchanges in the school between teachers and all the people who take care medically of the child. We report our experience in Centre Léon-Bérard of Lyon, concerning 38 children with brain tumors (102 meetings). Though difficult to assess scientifically, the benefit from these meetings is obvious. For the teachers: the knowledge and understanding of the physiopathology of brain tumors and secondary sequellae facilitates teaching. For the child: the disappearance of surrounding fears and fantasms make life easier. This experience is so rich that it should be extended to other pathologies.

(Surface engineering by high energy beams)

DOE Office of Scientific and Technical Information (OSTI.GOV)

McHargue, C.J.

1989-10-23

A paper entitled Structure-Mechanical Property relationships in Ion-Implanted Ceramics'' was presented at the 2nd International Seminar on Surface Engineering by High Energy Beams in Lisbon, Portugal. This seminar was sponsored by the International Federation of Heat Treatment and Surface Engineering and included discussions on surface modifications using laser, electron, and ion beams. The visit to the University of Lisbon and LNETI-Sacavem included discussions regarding collaborative research in which Professor J.C. Soares and Dr. M.F. da Silva would conduct perturbed angular correlation (PAC) studies on ion-implanted samples supplied by the traveler. The collaboration between researchers at ORNL and the University Claudemore » Bernard-Lyon 1 (France) continues. Data were analyzed during this visit, plans for further experiments were developed, and a paper was drafted for publication.« less

Grid-Scale Energy Storage Demonstration of Ancillary Services Using the UltraBattery Technology

DOE Office of Scientific and Technical Information (OSTI.GOV)

Seasholtz, Jeff

2015-08-20

The collaboration described in this document is being done as part of a cooperative research agreement under the Department of Energy’s Smart Grid Demonstration Program. This document represents the Final Technical Performance Report, from July 2012 through April 2015, for the East Penn Manufacturing Smart Grid Program demonstration project. This Smart Grid Demonstration project demonstrates Distributed Energy Storage for Grid Support, in particular the economic and technical viability of a grid-scale, advanced energy storage system using UltraBattery ® technology for frequency regulation ancillary services and demand management services. This project entailed the construction of a dedicated facility on the Eastmore » Penn campus in Lyon Station, PA that is being used as a working demonstration to provide regulation ancillary services to PJM and demand management services to Metropolitan Edison (Met-Ed).« less

Assessing various approaches for flash flood forecasting in the Yzeron periurban catchment (150 km2) south-east Lyon, France

NASA Astrophysics Data System (ADS)

Braud, Isabelle; Breil, Pascal; Javelle, Pierre; Pejakovic, Nikola; Guérin, Stéphane

2017-04-01

The Yzeron periurban catchment (150 km2) is prone to flash floods leading to overflow in the downstream part of the catchment. A prevention and management plan has been approved and the set-up of a flood forecasting system is planned. The present study presents a comparison of several solutions for flood forecasting in the catchment. It is based on an extensive data collection (rain gauges, radar/rain gauge reanalyses, discharge and water level data) from this experimental catchment. A set of rainfall-runoff events leading to floods (problematic and non-problematic floods) was extracted and formed the basis for the definition of a first forecasting method. It is based on data analysis and the identification of explaining factors amongst the following: rainfall amount, intensity, antecedent rainfall, initial discharge. Several statistical methods including Factorial Analysis of Mixed Data and Classification and Regression Tree were used for this purpose. They showed that several classes of problematic floods can be identified. The first one is related to wet conditions characterized with high initial discharge and antecedent rainfall. The second class is driven by rainfall amount, initial discharge and rainfall intensity. Thresholds of these variables can be identified to provide a first warning. The second forecasting method assessed in the study is the system that will be operational in France in 2017, based on the AIGA method (Javelle et al., 2016). For this purpose, 18-year discharge simulation using the hydrological model of the AIGA method, forced using radar/rain gauges reanalysis were available at 44 locations within the catchment. The dates for which quantiles of a given return period were overtopped were identified and compared with the list of problematic events. The AIGA method was found relevant in identifying the most problematic events, but the lead time needs further investigation in order to assess the usefulness for population warning. References: Pierre Javelle, Didier Organde, Julie Demargne, Clotilde Saint-Martin, Céline de Saint-Aubin, Léa Garandeau and Bruno Janet (2016). Setting up a French national flash flood warning system for ungauged catchments based on the AIGA method. E3S Web of Conferences 7, 18010 (2016), 3rd European Conference on Flood Risk Management (FLOODrisk 2016), http://dx.doi.org/10.1051/e3sconf/20160718010

A Death Involving a Fired and Deflected Bullet: A Case Report from Lyon University Institute of Forensic Science, France.

PubMed

Maujean, Géraldine; Guinet, Tiphaine; Malicier, Daniel

2016-01-01

In case of gunshot deaths, atypical wounds can make the distinction between entrance and exit wounds harder. They may be due either to anatomical reasons or to diverse cogent ballistic arguments. The reported case pertains to a fatal hunting accident involving an expanded conical point bullet against the neck with both atypical entrance and exit wounds. Ballistic analyses including test firings allowed a better understanding of the external and internal findings. Upon premature impact with an intermediary target, the bullet experienced expansion in the formation of sharp brass petals responsible for a star-shaped entry wound. The trajectory of the deformed high energy projectile through the victim's body was then deviated by the cervical column, causing it to be tangential to the skin when exiting the body. The description of such atypical cases may benefit other experts and may assist in their investigation into similar cases. © 2015 American Academy of Forensic Sciences.

Leeds-Lyon Symposium on Tribology ’The Tribology Design of Machine Elements’ (15th) 6-9 September 1988

DTIC Science & Technology

1988-08-01

bearing radius 6 ILuR Radial bl 󈧎 :radial clearance A- l a0 a a 1+ b2 U: bearing speed ,. hto p, : ar "ess. 9. Aiscocity b2 b1 Fig. 1 Bearing...priorarrangement for football/ rugby /hockey/cricket, with charges beingade dependent upon playing numbers and duration of time in use. A large sports pavilion

Etude numerique et experimentale de la reponse vibro-acoustique des structures raidies a des excitations aeriennes et solidiennes

NASA Astrophysics Data System (ADS)

Mejdi, Abderrazak

Les fuselages des avions sont generalement en aluminium ou en composite renforces par des raidisseurs longitudinaux (lisses) et transversaux (cadres). Les raidisseurs peuvent etre metalliques ou en composite. Durant leurs differentes phases de vol, les structures d'avions sont soumises a des excitations aeriennes (couche limite turbulente : TBL, champs diffus : DAF) sur la peau exterieure dont l'energie acoustique produite se transmet a l'interieur de la cabine. Les moteurs, montes sur la structure, produisent une excitation solidienne significative. Ce projet a pour objectifs de developper et de mettre en place des strategies de modelisations des fuselages d'avions soumises a des excitations aeriennes et solidiennes. Tous d'abord, une mise a jour des modeles existants de la TBL apparait dans le deuxieme chapitre afin de mieux les classer. Les proprietes de la reponse vibro-acoustique des structures planes finies et infinies sont analysees. Dans le troisieme chapitre, les hypotheses sur lesquelles sont bases les modeles existants concernant les structures metalliques orthogonalement raidies soumises a des excitations mecaniques, DAF et TBL sont reexamines en premier lieu. Ensuite, une modelisation fine et fiable de ces structures est developpee. Le modele est valide numeriquement a l'aide des methodes des elements finis (FEM) et de frontiere (BEM). Des tests de validations experimentales sont realises sur des panneaux d'avions fournis par des societes aeronautiques. Au quatrieme chapitre, une extension vers les structures composites renforcees par des raidisseurs aussi en composites et de formes complexes est etablie. Un modele analytique simple est egalement implemente et valide numeriquement. Au cinquieme chapitre, la modelisation des structures raidies periodiques en composites est beaucoup plus raffinee par la prise en compte des effets de couplage des deplacements planes et transversaux. L'effet de taille des structures finies periodiques est egalement pris en

Monitoring and Evaluation of Yearling Fall Chinook Salmon Released from Acclimation Facilities Upstream of Lower Granite Dam; 1998 Annual Report.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rocklage, Stephen J.

The Nez Perce Tribe, in cooperation with the U.S. Fish and Wildlife Service and Washington Department of Fish and Wildlife, conducted monitoring and evaluation studies on Lyons Ferry Hatchery (Snake River stock) yearling fall chinook salmon that were acclimated and released at three Fall Chinook Acclimation Project sites upstream of Lower Granite Dam along with yearlings released on-station from Lyons Ferry Hatchery in 1998. The three fall chinook acclimation facilities are operated by the Nez Perce Tribe and located at Pittsburg Landing and Captain John Rapids on the Snake River and at Big Canyon Creek on the Clearwater River. Yearlingsmore » at the Big Canyon facility consisted of two size classes that are referred to in this report as 9.5 fish per pound (fpp) and 30 fpp. The Big Canyon 9.5 fpp were comparable to the yearlings at Pittsburg Landing, Captain John Rapids and Lyons Ferry Hatchery. A total of 9,942 yearlings were PIT tagged and released at Pittsburg Landing. PIT tagged yearlings had a mean fork length of 159.9 mm and mean condition factor of 1.19. Of the 9,942 PIT tagged fish released, a total of 6,836 unique tags were detected at mainstem Snake and Columbia River dams (Lower Granite, Little Goose, Lower Monumental and McNary). A total of 4,926 9.5 fpp and 2,532 30 fpp yearlings were PIT tagged and released at Big Canyon. PIT tagged 9.5 fpp yearlings had a mean fork length of 156.9 mm and mean condition factor of 1.13. PIT tagged 30 fpp yearlings had a mean fork length of 113.1 mm and mean condition factor of 1.18. Of the 4,926 PIT tagged 9.5 fpp yearlings released, a total of 3,042 unique tags were detected at mainstem Snake and Columbia River dams. Of the 2,532 PIT tagged 30 fpp yearlings released, a total of 1,130 unique tags were detected at mainstem Snake and Columbia River dams. A total of 1,253 yearlings were PIT tagged and released at Captain John Rapids. PIT tagged yearlings had a mean fork length of 147.5 mm and mean condition factor of 1

Etude de l'amelioration de la qualite des anodes par la modification des proprietes du brai

NASA Astrophysics Data System (ADS)

Bureau, Julie

La qualite des anodes produites se doit d'etre bonne afin d'obtenir de l'aluminium primaire tout en reduisant le cout de production du metal, la consommation d'energie et les emissions environnementales. Or, l'obtention des proprietes finales de l'anode necessite une liaison satisfaisante entre le coke et le brai. Toutefois, la matiere premiere actuelle n'assure pas forcement la compatibilite entre le coke et le brai. Une des solutions les plus prometteuses, pour ameliorer la cohesion entre ces deux materiaux, est la modification des proprietes du brai. L'objectif de ce travail consiste a modifier les proprietes du brai par l'ajout d'additifs chimiques afin d'ameliorer la mouillabilite du coke par le brai modifie pour produire des anodes de meilleure qualite. La composition chimique du brai est modifiee en utilisant des tensioactifs ou agents de modification de surface choisis dans le but d'enrichir les groupements fonctionnels susceptibles d'ameliorer la mouillabilite. L'aspect economique, l'empreinte environnementale et l'impact sur la production sont consideres dans la selection des additifs chimiques. Afin de realiser ce travail, la methodologie consiste a d'abord caracteriser les brais non modifies, les additifs chimiques et les cokes par la spectroscopie infrarouge a transformee de Fourier (FTIR) afin d'identifier les groupements chimiques presents. Puis, les brais sont modifies en ajoutant un additif chimique afin de possiblement modifier ses proprietes. Differentes quantites d'additif sont ajoutees afin d'examiner l'effet de la variation de la concentration sur les proprietes du brai modifie. La methode FTIR permet d'evaluer la composition chimique des brais modifies afin de constater si l'augmentation de la concentration d'additif enrichit les groupements fonctionnels favorisant l'adhesion coke/brai. Ensuite, la mouillabilite du coke par le brai est observee par la methode goutte- sessile. Une amelioration de la mouillabilite par la modification a l'aide d

Quantification des besoins en intrants antipaludiques: contribution à l'actualisation des hypothèses pour la quantification des intrants de prise en charge des cas de paludisme grave en République Démocratique du Congo

PubMed Central

Likwela, Joris Losimba; Otokoye, John Otshudiema

2015-01-01

Les formes graves de paludisme à Plasmodium falciparum sont une cause majeure de décès des enfants de moins de 5 ans en Afrique Sub-saharienne. Un traitement rapide dépend de la disponibilité de médicaments appropriés au niveau des points de prestation de service. La fréquence des ruptures de stock des commodités antipaludiques, en particuliers celles utilisées pour le paludisme grave, avait nécessité une mise à jour des hypothèses de quantification. Les données issues de la collecte de routine du PNLP de 2007 à 2012 ont été comparées à celles rapportés par d'autres pays africains et utilisées pour orienter les discussions au cours d'un atelier organisé par le PNLP et ses partenaires techniques et financiers afin de dégager un consensus national. La proportion des cas de paludisme rapportés comme grave en RDC est resté autour d'une médiane de 7% avec un domaine de variation de 6 à 9%. Hormis la proportion rapportée au Kenya (2%), les pays africains ont rapporté une proportion de cas grave variant entre 5 et 7%. Il apparaît que la proportion de 1% précédemment utilisée pour la quantification en RDC a été sous-estimée dans le contexte de la gestion des cas graves sur terrain. Un consensus s'est dégagé autour de la proportion de 5% étant entendu que des efforts de renforcement des capacités seraient déployés afin d'améliorer le diagnostic au niveau des points de prestation des services. PMID:26213595

Les effets des interfaces sur les proprietes magnetiques et de transport des multicouches nickel/iron et cobalt/silver

NASA Astrophysics Data System (ADS)

Veres, Teodor

Cette these est consacree a l'etude de l'evolution structurale des proprietes magnetiques et de transport des multicouches Ni/Fe et nanostructures a base de Co et de l'Ag. Dans une premiere partie, essentiellement bibliographique, nous introduisons quelques concepts de base relies aux proprietes magnetiques et de transport des multicouches metalliques. Ensuite, nous presentons une breve description des methodes d'analyse des resultats. La deuxieme partie est consacree a l'etude des proprietes magnetiques et de transport des multicouches ferromagnetiques/ferromagnetiques Ni/Fe. Nous montrerons qu'une interpretation coherente de ces proprietes necessite la prise en consideration des effets des interfaces. Nous nous attacherons a mettre en evidence, a evaluer et a etudier les effets de ces interfaces ainsi que leur evolution, et ce, suite a des traitements thermiques tel que le depot a temperature elevee et l'irradiation ionique. Les analyses correlees de la structure et de la magnetoresistance nous permettront d'emettre des conclusions sur l'influence des couches tampons entre l'interface et le substrat ainsi qu'entre les couches elles-memes sur le comportement magnetique des couches F/F. La troisieme partie est consacree aux systemes a Magneto-Resistance Geante (MRG) a base de Co et Ag. Nous allons etudier l'evolution de la microstructure suite a l'irradiation avec des ions Si+ ayant une energie de 1 MeV, ainsi que les effets de ces changements sur le comportement magnetique. Cette partie debutera par l'analyse des proprietes d'une multicouche hybride, intermediaire entre les multicouches et les materiaux granulaires. Nous analyserons a l'aide des mesures de diffraction, de relaxation superparamagnetique et de magnetoresistance, les evolutions structurales produites par l'irradiation ionique. Nous etablirons des modeles qui nous aideront a interpreter les resultats pour une serie des multicouches qui couvrent un large eventail de differents comportements magnetiques

Caracterisation des proprietes acoustiques des materiaux poreux a cellules ouvertes et a matrice rigide ou souple

NASA Astrophysics Data System (ADS)

Salissou, Yacoubou

L'objectif global vise par les travaux de cette these est d'ameliorer la caracterisation des proprietes macroscopiques des materiaux poreux a structure rigide ou souple par des approches inverses et indirectes basees sur des mesures acoustiques faites en tube d'impedance. La precision des approches inverses et indirectes utilisees aujourd'hui est principalement limitee par la qualite des mesures acoustiques obtenues en tube d'impedance. En consequence, cette these se penche sur quatre problemes qui aideront a l'atteinte de l'objectif global precite. Le premier probleme porte sur une caracterisation precise de la porosite ouverte des materiaux poreux. Cette propriete en est une de passage permettant de lier la mesure des proprietes dynamiques acoustiques d'un materiau poreux aux proprietes effectives de sa phase fluide decrite par les modeles semi-phenomenologiques. Le deuxieme probleme traite de l'hypothese de symetrie des materiaux poreux selon leur epaisseur ou un index et un critere sont proposes pour quantifier l'asymetrie d'un materiau. Cette hypothese est souvent source d'imprecision des methodes de caracterisation inverses et indirectes en tube d'impedance. Le critere d'asymetrie propose permet ainsi de s'assurer de l'applicabilite et de la precision de ces methodes pour un materiau donne. Le troisieme probleme vise a mieux comprendre le probleme de transmission sonore en tube d'impedance en presentant pour la premiere fois un developpement exact du probleme par decomposition d'ondes. Ce developpement permet d'etablir clairement les limites des nombreuses methodes existantes basees sur des tubes de transmission a 2, 3 ou 4 microphones. La meilleure comprehension de ce probleme de transmission est importante puisque c'est par ce type de mesures que des methodes permettent d'extraire successivement la matrice de transfert d'un materiau poreux et ses proprietes dynamiques intrinseques comme son impedance caracteristique et son nombre d'onde complexe. Enfin, le

Le role du phytoplancton de petite taille (<20 mum) dans les variations des proprietes optiques des eaux du Saint-Laurent

NASA Astrophysics Data System (ADS)

Mas, Sebastien

Les mesures satellitaires de couleur des oceans sont largement determinees par les proprietes optiques inherentes (IOPs) des eaux de surface. D'autre part, le phytoplancton de petite taille (<20 mum) est le plus souvent dominant dans les oceans, et peut donc etre une source importante de variation des IOPs dans les oceans. Dans ce contexte, le but principal de ce doctorat etait de definir l'impact du phytoplancton (<20 mum) sur les variations des proprietes optiques de l'Estuaire et du Golfe du Saint-Laurent (Canada). Afin d'atteindre cet objectif, il etait necessaire de determiner en milieu controle les facteurs de variabilite des proprietes optiques cellulaires et des IOPs du phytoplancton (<20 mum) des eaux du Saint-Laurent, et d'evaluer la contribution du phytoplancton (<20 mum) aux proprietes optiques totales des eaux du Saint-Laurent. Des experiences en laboratoire ont montre que les variations des proprietes optiques des cellules phytoplanctoniques soumises a un cycle jour-nuit, ainsi qu'a des changements concomitants d'intensite lumineuse, peuvent contribuer significativement a la variabilite des proprietes optiques observee en milieu naturel. D'autres experiences ont, quant a elles, mis en evidence que les variations des proprietes optiques des cellules phytoplanctoniques dues aux phases de croissance peuvent alterer les IOPs des oceans, particulierement pendant les periodes de floraison. De plus, la presence de bacteries et de particules detritiques peut egalement affecter la variabilite des IOPs totales, notamment la diffusion. Au printemps, dans l'Estuaire et le Golfe du Saint-Laurent, la contribution du phytoplancton <20 mum aux IOPs presentait des differences regionales evidentes pour les proprietes d'absorption et de diffusion. En plus de la variabilite spatiale, les proprietes optiques cellulaires presentaient des variations journalieres, et ce particulierement pour le picophytoplancton. Enfin, la plupart des differences observees dans les

[JACIE: from guidelines to clinical practice and continuous quality improvement, the Léon-Bérard cancer center experience].

PubMed

Donot, Pierre Emmanuel

2009-01-01

JACIE, a European certification program for stem cell transplantation, has now been recognized by the French Health Authorities. It can be considered as an evaluation of professional practice, an activity that can be promoted by health centres. The present article has two aims: firstly, it describes the structure of the certification standard based on the relative structure of each of its components; secondly, it reports on the experience acquired by the Léon-Bérard cancer centre (Lyon-France) during the certification of its own stem cell transplantation program. The JACIE manual written in English is divided into three parts corresponding to the three processes identified. Part B describes the clinical haematopoietic stem cell transplantation program. Part C is dedicated to the collection of haematopoietic stem cells from blood and marrow. Finally, part D applies to the cell therapy laboratory in charge of cell preservation and the preparation of grafts for re-infusion. After the application has been submitted to the JACIE board, a date is set for an inspection visit. The cell therapy laboratory at Léon-Bérard cancer centre has already participated to a certified transplantation project of the Edouard-Herriot Hospital (Lyon public hospitals) [parts C and D of the certification]. The executive board proposed that the clinical haematology unit of the cancer centre also applied for JACIE certification. A multidisciplinary work group-combining document writing skills and a real capacity to convince and motivate clinical staff was formed. Secondly, a comprehensive collection of existing documents was issued and the clinical pathway of the patients was formalized so that no step of the graft process would be omitted. A physician from another hospital also tested the evaluation process with the organisation of a mock visit. He confirmed that everything was in good way and provided recommendations to improve the program. This huge preparation provided invaluable

Using hand proportions to test taxonomic boundaries within the Tupaia glis species complex (Scandentia, Tupaiidae)

USGS Publications Warehouse

Sargos, Eric J.; Woodman, Neal; Reese, Aspen T.; Olson, Link E.

2013-01-01

Treeshrews (order Scandentia) comprise 2 families of squirrel-sized terrestrial, arboreal, and scansorial mammals distributed throughout much of tropical South and Southeast Asia. The last comprehensive taxonomic revision of treeshrews was published in 1913, and a well-supported phylogeny clarifying relationships among all currently recognized extant species within the order has only recently been published. Within the family Tupaiidae, 2 widely distributed species, the northern treeshrew, Tupaia belangeri (Wagner, 1841), and the common treeshrew, T. glis (Diard, 1820), represent a particularly vexing taxonomic complex. These 2 species are currently distinguished primarily based on their respective distributions north and south of the Isthmus of Kra on the Malay Peninsula and on their different mammae counts. This problematic species complex includes 54 published synonyms, many of which represent putative island endemics. The widespread T. glis and T. belangeri collectively comprise a monophyletic assemblage representing the sister lineage to a clade composed of the golden-bellied treeshrew, T. chrysogaster Miller, 1903 (Mentawai Islands), and the long-footed treeshrew, T. longipes (Thomas, 1893) (Borneo). As part of a morphological investigation of the T. glis–T. belangeri complex, we studied the proportions of hand bones, which have previously been shown to be useful in discriminating species of soricids (true shrews). We measured 38 variables from digital X-ray images of 148 museum study skins representing several subspecies of T. glis, T. belangeri, T. chrysogaster, and T. longipes and analyzed these data using principal components and cluster analyses. Manus proportions among these 4 species readily distinguish them, particularly in the cases of T. chrysogaster and T. longipes. We then tested the distinctiveness of several of the populations comprising T. glis and T. longipes. T. longipes longipes and T. l. salatana Lyon, 1913, are distinguishable from each

Elemental and isotopic behaviour of Zn in Deccan basalt weathering profiles: Chemical weathering from bedrock to laterite and links to Zn deficiency in tropical soils.

PubMed

Suhr, Nils; Schoenberg, Ronny; Chew, David; Rosca, Carolina; Widdowson, Mike; Kamber, Balz S

2018-04-01

Zinc (Zn) is a micronutrient for organisms and essential for plant growth, therefore knowledge of its elemental cycling in the surface environment is important regarding wider aspects of human nutrition and health. To explore the nature of Zn cycling, we compared its weathering behaviour in a sub-recent regolith versus an ancient laterite profile of the Deccan Traps, India - an area of known soil Zn deficiency. We demonstrate that progressive breakdown of primary minerals and the associated formation of phyllosilicates and iron oxides leads to a depletion in Zn, ultimately resulting in a loss of 80% in lateritic residues. This residue is mainly composed of resistant iron oxides and hydroxides ultimately delivering insufficient amounts of bio-available Zn. Moreover, (sub)-tropical weathering in regions experiencing extended tectonic quiescence (e.g., cratons) further enhance the development of old and deep soil profiles that become deficient in Zn. This situation is clearly revealed by the spatial correlation of the global distribution of laterites, cratons (Africa, India, South America and Australia) and known regions of Zn deficient soils that result in health problems for humans whose diet is derived from such land. We also investigate whether this elemental depletion of Zn is accompanied by isotope fractionation. In the saprolitic horizons of both weathering profiles, compositions of δ 66 Zn JMC-Lyon lie within the "crustal average" of +0.27±0.07‰ δ 66 Zn JMC-Lyon . By contrast, soil horizons enriched in secondary oxides show lighter isotope compositions. The isotopic signature of Zn (Δ 66 Zn sample-protolith up to ~ -0.65‰) during the formation of the ferruginous-lateritic weathering profile likely resulted from a combination of biotically- and kinetically-controlled sorption reactions on Fe-oxyhydroxides. Our findings suggest that oxide rich soil types/horizons in (sub)-tropical regions likely exert a control on riverine Zn isotope compositions such

Enhancement of Customary Dermoscopy Education With Spaced Education e-Learning: A Prospective Controlled Trial.

PubMed

Boespflug, Amélie; Guerra, José; Dalle, Stéphane; Thomas, Luc

2015-08-01

Dermoscopy permits the detection of early-stage melanomas but is difficult to learn. It is important to develop effective teaching methods. Spaced education is a methodology within the field of adaptive learning that uses online tools to reinforce long-term retention. To determine whether a spaced education dermoscopy module improved dermoscopy skills in the continuing medical education setting and to evaluate participant satisfaction. We designed a prospective controlled study with 2 sequential cohorts of participants enrolled between September 2010 and September 2013, in the continuing medical education dermoscopy program of the Claude Bernard-Lyon 1 University in Lyon, France. Participants enrolled in this program were either certified dermatologists or senior dermatology residents. The control group (n = 95) comprised all participants enrolled during the 2 first years of the study (49 participants in the class of 2010, 46 in the class of 2011). The intervention group (n = 96) comprised all participants enrolled during the third and fourth years of the study (46 in the class of 2012; 50 in the class of 2013). All participants attended a 3-day lecture followed by small-group tutorials 4 months later. Each participant also attended a day of consultation with a dermoscopy specialist. In addition, participants in the intervention group were enrolled in an e-learning spaced education dermoscopy program. The main outcome measure was mean participant scores at the posttest evaluation, which was conducted 4 months after course enrollment. The intervention group had better results at the posttest, with a mean (SD) score (out of a possible 160.0 points) of 148.1 (5.8) (n = 82 participants) vs 145.7 (7.7) (n = 90 participants) in the control group (P = .02). Ninety-two percent of the participants (80 of 87) were extremely or very satisfied with the e-learning module. Participant engagement was high, with an average of 85% of participants (80 of 94) "on

Prevalence and covariates of electrocardiographic left ventricular hypertrophy in diabetic patients in Tanzania

PubMed Central

Lutale, JJK; Thordarson, H; Gulam-Abbas, Z; Vetvik, K; Gerdts, E

2008-01-01

Summary Background Left ventricular hypertrophy (LV H) has been demonstrated to be a powerful predictor of cardiovascular (CV) morbidity and mortality in diabetic as well as hypertensive patients. However, less is known about the prevalence of electrocardiographic LV H (ECG-LV H) and its relation to other CV risk factors in diabetic patients in sub-Saharan Africa. Therefore, the aim was to assess the prevalence of ECG-LV H in diabetic patients in Dar es Salaam, Tanzania, and its relation to other cardiovascular risk factors. Methods Two hundred and thirty-seven consecutive patients attending the Muhimbili diabetic clinic were studied. ECG-LVH was diagnosed by Sokolow-Lyon voltage and Cornell voltage-duration product criteria. Q waves, ST-segment deviation, T-wave abnormalities and intraventricular conduction defects were classified by the Minnesota codes. Blood pressure (BP), serum creatinine, cholesterol and triglyceride levels, and HbA1c and urinary albumin and creatinine concentrations were determined. Results The prevalence of LV H in patients was 16% by either ECG criteria; 12.2% by Sokolow-Lyon and 5.1% by Cornell product criteria. Patients with LV H had significantly higher systolic and mean BP and pulse pressure, and a higher prevalence of ST-segment abnormalities, T-wave inversion and albuminuria than those without LV H (all p < 0.05). In multivariate logistic regression analysis, systolic BP was the only independent predictor of ECG-LV H. The prevalence of ECG-LV H increased by 15% per 10 mmHg higher systolic BP [OR 1.151 (95% CI 1.00921.314), p < 0.05]. Clustering of cardiovascular risk factors differed significantly between type 1 and type 2 diabetes patients. On average, type 1 patients had 0.8 and type 2 had 2.2 additional CV risk factors. Conclusion ECG-LV H was present in 16% of diabetic patients in Tanzania. Systolic BP was the most important predictor of ECG-LV H. Clustering of CV risks was significantly higher in type 2 than in type 1 diabetics

The desA and desB genes from Clostridium scindens ATCC 35704 encode steroid-17,20-desmolase.

PubMed

Devendran, Saravanan; Mythen, Sean M; Ridlon, Jason M

2018-06-01

Clostridium scindens is a gut microbe capable of removing the side-chain of cortisol, forming 11β-hydro-xyandrostenedione. A cortisol-inducible operon ( desABCD ) was previously identified in C. scindens ATCC 35704 by RNA-Seq. The desC gene was shown to encode a cortisol 20α-hydroxysteroid dehydrogenase (20α-HSDH). The desD encodes a protein annotated as a member of the major facilitator family, predicted to function as a cortisol transporter. The desA and desB genes are annotated as N-terminal and C-terminal transketolases, respectively. We hypothesized that the DesAB forms a complex and has steroid-17,20-desmolase activity. We cloned the desA and desB genes from C. scindens ATCC 35704 in pETDuet for overexpression in Escherichia coli The purified recombinant DesAB was determined to be a 142 ± 5.4 kDa heterotetramer. We developed an enzyme-linked continuous spectrophotometric assay to quantify steroid-17,20-desmolase. This was achieved by coupling DesAB-dependent formation of 11β-hydroxyandrostenedione with the NADPH-dependent reduction of the steroid 17-keto group by a recombinant 17β-HSDH from the filamentous fungus, Cochliobolus lunatus The pH optimum for the coupled assay was 7.0 and kinetic constants using cortisol as substrate were K m of 4.96 ± 0.57 µM and k cat of 0.87 ± 0.076 min -1 Substrate-specificity studies revealed that rDesAB recognized substrates regardless of 11β-hydroxylation, but had an absolute requirement for 17,21-dihydroxy 20-ketosteroids. Copyright © 2018 Devendran et al.

The model SIRANE for atmospheric urban pollutant dispersion. PART III: Validation against NO2 yearly concentration measurements in a large urban agglomeration

NASA Astrophysics Data System (ADS)

Soulhac, L.; Nguyen, C. V.; Volta, P.; Salizzoni, P.

2017-10-01

We present a validation study of an updated version of the SIRANE model, whose results have been systematically compared to concentrations of nitrogen dioxide collected over the whole urban agglomeration of Lyon. We model atmospheric dispersion of nitrogen oxides emitted by road traffic, industries and domestic heating. The meteorological wind field is computed by a pre-processor using data collected at a ground level monitoring station. Model results are compared with hourly concentrations measured at 15 monitoring stations over the whole year (2008). Further 75 passive diffusion samplers were used during 3 periods of 2 weeks to get a detailed spatial distribution over the west part of the city. An analysis of the model results depending on the variability of the meteorological input allows us to identify the causes for peculiar bad performances of the model and to identify possible improvements of the parameterisations implemented in it.

Evaluation of Ecotoxicological Risks Related to the Discharge of Combined Sewer Overflows (CSOs) in a Periurban River

PubMed Central

Angerville, Ruth; Perrodin, Yves; Bazin, Christine; Emmanuel, Evens

2013-01-01

Discharges of Combined Sewer Overflows (CSOs) into periurban rivers present risks for the concerned aquatic ecosystems. In this work, a specific ecotoxicological risk assessment methodology has been developed as management tool to municipalities equipped with CSOs. This methodology comprises a detailed description of the spatio-temporal system involved, the choice of ecological targets to be preserved, and carrying out bioassays adapted to each compartment of the river receiving CSOs. Once formulated, this methodology was applied to a river flowing through the outskirts of the city of Lyon in France. The results obtained for the scenario studied showed a moderate risk for organisms of the water column and a major risk for organisms of the benthic and hyporheic zones of the river. The methodology enabled identifying the critical points of the spatio-temporal systems studied, and then making proposals for improving the management of CSOs. PMID:23812025

CROSSOVERS BETWEEN EPIGENESIS AND EPIGENETICS. A MULTICENTER APPROACH TO THE HISTORY OF EPIGENETICS (1901-1975).

PubMed

Costa, Rossella; Frezza, Giulia

2014-01-01

The origin of epigenetics has been traditionally traced back to Conrad Hal Waddington's foundational work in 1940s. The aim of the present paper is to reveal a hidden history of epigenetics, by means of a multicenter approach. Our analysis shows that genetics and embryology in early XX century--far from being non-communicating vessels--shared similar questions, as epitomized by Thomas Hunt Morgan's works. Such questions were rooted in the theory of epigenesis and set the scene for the development of epigenetics. Since the 1950s, the contribution of key scientists (Mary Lyon and Eduardo Scarano), as well as the discussions at the international conference of Gif-sur-Yvette (1957) paved the way for three fundamental shifts of focus: 1. From the whole embryo to the gene; 2. From the gene to the complex extranuclear processes of development; 3. From cytoplasmic inheritance to the epigenetics mechanisms.

RiboDB Database: A Comprehensive Resource for Prokaryotic Systematics.

PubMed

Jauffrit, Frédéric; Penel, Simon; Delmotte, Stéphane; Rey, Carine; de Vienne, Damien M; Gouy, Manolo; Charrier, Jean-Philippe; Flandrois, Jean-Pierre; Brochier-Armanet, Céline

2016-08-01

Ribosomal proteins (r-proteins) are increasingly used as an alternative to ribosomal rRNA for prokaryotic systematics. However, their routine use is difficult because r-proteins are often not or wrongly annotated in complete genome sequences, and there is currently no dedicated exhaustive database of r-proteins. RiboDB aims at fulfilling this gap. This weekly updated comprehensive database allows the fast and easy retrieval of r-protein sequences from publicly available complete prokaryotic genome sequences. The current version of RiboDB contains 90 r-proteins from 3,750 prokaryotic complete genomes encompassing 38 phyla/major classes and 1,759 different species. RiboDB is accessible at http://ribodb.univ-lyon1.fr and through ACNUC interfaces. © The Author 2016. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Network image data bank prototype: the RSI project (Resume de Sortie Images)

NASA Astrophysics Data System (ADS)

Abouchi, Nacer; Jourlin, Michel; Bohbot, Oriana; Faurie, Catherine; Grisel, Richard

1995-02-01

The Hospital Edouard Herriot in Lyon and 3M company, associated with the Electronic Department of Physics Chimics and Electronic Engineering School (CPE), decided in 1993 to begin a study on a project of image network. This project is composed of many practical applications to be checked one by one. The purpose of this paper is to discuss the context, which is kind of small picture archiving and communication system (PACS), to explain the methodology which has been used related to hardware and software implementation, and to give examples of the first results obtained. One of the main interests of the results is the possibility to obtain on the same support, 3M laser imager, a film including images from different modalities and abstract summing up the patient stay in the hospital. The framework used is built around Omnis7 and C++ language on a PC computer.

Biosensors in Clinical Practice: Focus on Oncohematology

PubMed Central

Fracchiolla, Nicola S.; Artuso, Silvia; Cortelezzi, Agostino

2013-01-01

Biosensors are devices that are capable of detecting specific biological analytes and converting their presence or concentration into some electrical, thermal, optical or other signal that can be easily analysed. The first biosensor was designed by Clark and Lyons in 1962 as a means of measuring glucose. Since then, much progress has been made and the applications of biosensors are today potentially boundless. This review is limited to their clinical applications, particularly in the field of oncohematology. Biosensors have recently been developed in order to improve the diagnosis and treatment of patients affected by hematological malignancies, such as the biosensor for assessing the in vitro pre-treatment efficacy of cytarabine in acute myeloid leukemia, and the fluorescence resonance energy transfer-based biosensor for assessing the efficacy of imatinib in chronic myeloid leukemia. The review also considers the challenges and future perspectives of biosensors in clinical practice. PMID:23673681

Molecular insights into the biology of Greater Sage-Grouse

USGS Publications Warehouse

Oyler-McCance, Sara J.; Quinn, Thomas W.

2011-01-01

Recent research on Greater Sage-Grouse (Centrocercus urophasianus) genetics has revealed some important findings. First, multiple paternity in broods is more prevalent than previously thought, and leks do not comprise kin groups. Second, the Greater Sage-Grouse is genetically distinct from the congeneric Gunnison sage-grouse (C. minimus). Third, the Lyon-Mono population in the Mono Basin, spanning the border between Nevada and California, has unique genetic characteristics. Fourth, the previous delineation of western (C. u. phaios) and eastern Greater Sage-Grouse (C. u. urophasianus) is not supported genetically. Fifth, two isolated populations in Washington show indications that genetic diversity has been lost due to population declines and isolation. This chapter examines the use of molecular genetics to understand the biology of Greater Sage-Grouse for the conservation and management of this species and put it into the context of avian ecology based on selected molecular studies.

Effets des electrons secondaires sur l'ADN

NASA Astrophysics Data System (ADS)

Boudaiffa, Badia

Les interactions des electrons de basse energie (EBE) representent un element important en sciences des radiations, particulierement, les sequences se produisant immediatement apres l'interaction de la radiation ionisante avec le milieu biologique. Il est bien connu que lorsque ces radiations deposent leur energie dans la cellule, elles produisent un grand nombre d'electrons secondaires (4 x 104/MeV), qui sont crees le long de la trace avec des energies cinetiques initiales bien inferieures a 20 eV. Cependant, il n'y a jamais eu de mesures directes demontrant l'interaction de ces electrons de tres basse energie avec l'ADN, du principalement aux difficultes experimentales imposees par la complexite du milieu biologique. Dans notre laboratoire, les dernieres annees ont ete consacrees a l'etude des phenomenes fondamentaux induits par impact des EBE sur differentes molecules simples (e.g., N2, CO, O2, H2O, NO, C2H 4, C6H6, C2H12) et quelques molecules complexes dans leur phase solide. D'autres travaux effectues recemment sur des bases de l'ADN et des oligonucleotides ont montre que les EBE produisent des bris moleculaires sur les biomolecules. Ces travaux nous ont permis d'elaborer des techniques pour mettre en evidence et comprendre les interactions fondamentales des EBE avec des molecules d'interet biologique, afin d'atteindre notre objectif majeur d'etudier l'effet direct de ces particules sur la molecule d'ADN. Les techniques de sciences des surfaces developpees et utilisees dans les etudes precitees peuvent etre etendues et combinees avec des methodes classiques de biologie pour etudier les dommages de l'ADN induits par l'impact des EBE. Nos experiences ont montre l'efficacite des electrons de 3--20 eV a induire des coupures simple et double brins dans l'ADN. Pour des energies inferieures a 15 eV, ces coupures sont induites par la localisation temporaire d'un electron sur une unite moleculaire de l'ADN, ce qui engendre la formation d'un ion negatif transitoire

Evaluation des apports solaires a l'echelle d'un quartier urbain en periode de chauffe selon sa typologie, son orientation et sa latitude dans un contexte de densification de la ville

NASA Astrophysics Data System (ADS)

Chenard, Laurent

Mass urbanization is a major issue for town administrators. Population increase will have an impact on the quality of the environment for citizens. Government will have to take decisions to limit those effects. Green energies are part of the solution to reach fixed goals by the public administration for sustainable development. Passive solar energy is studied in this work in an urban canopy located in five different towns: San Francisco, Montreal, Bordeaux, Lyon and Stockholm. Passive solar energy is calculated in the heating season. Direct and diffuse solar radiation is considered by using the Perez model. Radiosity is not taken into account. Heating demand is calculated by the heating degree day method. Seven urban forms have been created to determine the amount of solar energy entering in every window of the urban canopy while taking into account urban context and forms. Optimal orientation of the canopy shows an increase of 5% of the passive solar radiation from original orientation, 180 degrees rotation from first orientation straight south. This value goes lower when stories are added to the urban context. A rotation of 90 degrees from the first orientation shows a decrease of 6 to 15% in solar passive gain. Densification of the urban canopy by adding stories to the buildings results in a loss up to 65% of the solar gain for the first story. It is showed that solar passive energy has a low ratio of 5% for space heating for old buildings, 1960 constructions. Today's buildings have a difference between passive solar energy and heating demand of 10 to 75% depending on the model and location.

Aircraft Disinsection: A Guide for Military and Civilian Air Carriers (Desinsectisation des aeronefs: Un guide a l’intention des responsables des transports aeriens civils et militaires)

DTIC Science & Technology

1996-04-01

regulations. - Ceratitis capitata (Mediterranean fruit fly). Quarantine regulations generally reduce - Rhagoletis pomonella (Apple maggot). the chances of a...d’insectes nuisibles dans un pays, en 6vitant des risques pour la sant6 des 6quipages, pour la s~curit6 de 1’a~ronef et pour l’industrie. Ce rapport examine 1...diffrrents officiels responsables de la r~glementation des insectes nuisibles introduits, de l’inscription des pesticides et de leur utilisation en

Etude des phenomenes dynamiques ultrarapides et des caracteristiques impulsionnelles d'emission terahertz du supraconducteur YBCO

NASA Astrophysics Data System (ADS)

Savard, Stephane

Les premieres etudes d'antennes a base de supraconducteurs a haute temperature critique emettant une impulsion electromagnetique dont le contenu en frequence se situe dans le domaine terahertz remontent a 1996. Une antenne supraconductrice est formee d'un micro-pont d'une couche mince supraconductrice sur lequel un courant continu est applique. Un faisceau laser dans le visible est focalise sur le micro-pont et place le supraconducteur dans un etat hors-equilibre ou des paires sont brisees. Grace a la relaxation des quasiparticules en surplus et eventuellement de la reformation des paires supraconductrices, nous pouvons etudier la nature de la supraconductivite. L'analyse de la cinetique temporelle du champ electromagnetique emis par une telle antenne terahertz supraconductrice s'est averee utile pour decrire qualitativement les caracteristiques de celle-ci en fonction des parametres d'operation tels que le courant applique, la temperature et la puissance d'excitation. La comprehension de l'etat hors-equilibre est la cle pour comprendre le fonctionnement des antennes terahertz supraconductrices a haute temperature critique. Dans le but de comprendre ultimement cet etat hors-equilibre, nous avions besoin d'une methode et d'un modele pour extraire de facon plus systematique les proprietes intrinseques du materiau qui compose l'antenne terahertz a partir des caracteristiques d'emission de celle-ci. Nous avons developpe une procedure pour calibrer le spectrometre dans le domaine temporel en utilisant des antennes terahertz de GaAs bombarde aux protons H+ comme emetteur et detecteur. Une fois le montage calibre, nous y avons insere une antenne emettrice dipolaire de YBa 2Cu3O7-delta . Un modele avec des fonctions exponentielles de montee et de descente du signal est utilise pour lisser le spectre du champ electromagnetique de l'antenne de YBa 2Cu3O7-delta, ce qui nous permet d'extraire les proprietes intrinseques de ce dernier. Pour confirmer la validite du modele

Developpement d'une methode calorimetrique de mesure des pertes ac pour des rubans supraconducteurs a haute temperature critique

NASA Astrophysics Data System (ADS)

Dolez, Patricia

Le travail de recherche effectue dans le cadre de ce projet de doctorat a permis la mise au point d'une methode de mesure des pertes ac destinee a l'etude des supraconducteurs a haute temperature critique. Pour le choix des principes de cette methode, nous nous sommes inspires de travaux anterieurs realises sur les supraconducteurs conventionnels, afin de proposer une alternative a la technique electrique, presentant lors du debut de cette these des problemes lies a la variation du resultat des mesures selon la position des contacts de tension sur la surface de l'echantillon, et de pouvoir mesurer les pertes ac dans des conditions simulant la realite des futures applications industrielles des rubans supraconducteurs: en particulier, cette methode utilise la technique calorimetrique, associee a une calibration simultanee et in situ. La validite de la methode a ete verifiee de maniere theorique et experimentale: d'une part, des mesures ont ete realisees sur des echantillons de Bi-2223 recouverts d'argent ou d'alliage d'argent-or et comparees avec les predictions theoriques donnees par Norris, nous indiquant la nature majoritairement hysteretique des pertes ac dans nos echantillons; d'autre part, une mesure electrique a ete realisee in situ dont les resultats correspondent parfaitement a ceux donnes par notre methode calorimetrique. Par ailleurs, nous avons compare la dependance en courant et en frequence des pertes ac d'un echantillon avant et apres qu'il ait ete endommage. Ces mesures semblent indiquer une relation entre la valeur du coefficient de la loi de puissance modelisant la dependance des pertes avec le courant, et les inhomogeneites longitudinales du courant critique induites par l'endommagement. De plus, la variation en frequence montre qu'au niveau des grosses fractures transverses creees par l'endommagement dans le coeur supraconducteur, le courant se partage localement de maniere a peu pres equivalente entre les quelques grains de matiere

Cartographie des disques

NASA Astrophysics Data System (ADS)

Hameury, Jean-Marie

2001-01-01

Two techniques are frequently used to produce images of the accretion disc in an eclipsing binary: eclipse mapping and Doppler tomography. From the light curve, one can deduce the radial distribution of the effective temperature, assuming axial symmetry. On the other hand, from the variation of the line profile one can reconstruct an image in the velocity space, which can be converted into a real image if one knows the kinematics of the system. Deux techniques sont couramment utilisées pour obtenir des images des disques dans les systèmes binaires à éclipses. En utilisant la courbe de lumière, on peut remonter à la distribution radiale de la brillance de surface, en supposant que celle-ci a une symètrie axiale. D'autre part, les profils de raies renseignent sur la distribution de vitesse des régions émissives leur variation temporelle permet de réaliser une image dans l'espace des vitesses, que l'on peut ensuite transformer en carte dans l'espace (x,y) si on connaît la cinématique du système.

Effets perturbateurs endocriniens des pesticides organochlores.

PubMed

Charlier, C; Plomteux, G

2002-01-01

Xenoestrogens such organochlorine pesticides are known to induce changes in reproductive development, function or behaviour in wildlife. Because these compounds are able to modify the estrogens metabolism, or to compete with estradiol for binding to the estrogen receptor, it may be possible that these products affect the risk of developing impaired fertility, precocious puberty or some kinds of cancer in man. Le plus ancien récit de lutte contre la pollution remonte à une légende indienne racontant que la divinité Sing-bonga était incommodée par les émanations des fours dans lesquels les Asuras fondaient leurs métaux (1). Evidemment depuis, la problématique n-a cessé de s-accroître et la contamination de la Terre par de nombreux polluants est devenue aujourd-hui un problème majeur de notre Société. La protection de notre environnement est une question capitale qui doit être respectée malgré la pression économique actuelle et qui ne cessera de croître au cours des prochaines années même si l-identification objective et indiscutable de ce qui est essentiel - donc devant être prioritairement garanti sur la planète - est difficile à cerner (2). « Un oiseau en mauvais état ne pond pas de bons oeufs » disait un proverbe grec. Mais ce n-est qu-à partir de la seconde moitié du XXème siècle que les toxicologues ont commencé à identifier les effets qu-avaient entraînés à l-échelle mondiale les pollutions émises aux XIXème siècle sur la faune sauvage et sur le cheptel (3). L-histoire contemporaine des pesticides industriels commence vers 1874 (synthèse des organochlorés) et se poursuit tout au long de ces 2 siècles en passant par la synthèse des organophosphorés (1950), des carbamates (1970) et des pyréthroïdes (1975) (4). Le dichlorodiphényltrichloroéthane (DDT) a été synthétisé pour la première fois par un étudiant en cours de préparation de sa thèse de doctorat : Othmer Zeidler. La production, reprise par les

Identification des parametres du moteur de l'avion Cessna Citation X pour la phase de croisiere a partir des tests en vol et a base des reseaux de neurones =

NASA Astrophysics Data System (ADS)

Zaag, Mahdi

La disponibilite des modeles precis des avions est parmi les elements cles permettant d'assurer leurs ameliorations. Ces modeles servent a ameliorer les commandes de vol et de concevoir de nouveaux systemes aerodynamiques pour la conception des ailes deformables des avions. Ce projet consiste a concevoir un systeme d'identification de certains parametres du modele du moteur de l'avion d'affaires americain Cessna Citation X pour la phase de croisiere a partir des essais en vol. Ces essais ont ete effectues sur le simulateur de vol concu et fabrique par CAE Inc. qui possede le niveau D de la dynamique de vol. En effet, le niveau D est le plus haut niveau de precision donne par l'autorite federale de reglementation FAA de l'aviation civile aux Etats-Unis. Une methodologie basee sur les reseaux de neurones optimises a l'aide d'un algorithme intitule le "grand deluge etendu" est utilisee dans la conception de ce systeme d'identification. Plusieurs tests de vol pour differentes altitudes et differents nombres de Mach ont ete realises afin de s'en servir comme bases de donnees pour l'apprentissage des reseaux de neurones. La validation de ce modele a ete realisee a l'aide des donnees du simulateur. Malgre la nonlinearite et la complexite du systeme, les parametres du moteur ont ete tres bien predits pour une enveloppe de vol determinee. Ce modele estime pourrait etre utilise pour des analyses de fonctionnement du moteur et pourrait assurer le controle de l'avion pendant cette phase de croisiere. L'identification des parametres du moteur pourrait etre realisee aussi pour les autres phases de montee et de descente afin d'obtenir son modele complet pour toute l'enveloppe du vol de l'avion Cessna Citation X (montee, croisiere, descente). Cette methode employee dans ce travail pourrait aussi etre efficace pour realiser un modele pour l'identification des coefficients aerodynamiques du meme avion a partir toujours des essais en vol. None None None

Elaboration de nouvelles approches micromecaniques pour l'optimisation des performances mecaniques des materiaux heterogenes

NASA Astrophysics Data System (ADS)

Aboutajeddine, Ahmed

Les modeles micromecaniques de transition d'echelles qui permettent de determiner les proprietes effectives des materiaux heterogenes a partir de la microstructure sont consideres dans ce travail. L'objectif est la prise en compte de la presence d'une interphase entre la matrice et le renforcement dans les modeles micromecaniques classiques, de meme que la reconsideration des approximations de base de ces modeles, afin de traiter les materiaux multiphasiques. Un nouveau modele micromecanique est alors propose pour tenir compte de la presence d'une interphase elastique mince lors de la determination des proprietes effectives. Ce modele a ete construit grace a l'apport de l'equation integrale, des operateurs interfaciaux de Hill et de la methode de Mori-Tanaka. Les expressions obtenues pour les modules globaux et les champs dans l'enrobage sont de nature analytique. L'approximation de base de ce modele est amelioree par la suite dans un nouveau modele qui s'interesse aux inclusions enrobees avec un enrobage mince ou epais. La resolution utilisee s'appuie sur une double homogeneisation realisee au niveau de l'inclusion enrobee et du materiau. Cette nouvelle demarche, permettra d'apprehender completement les implications des approximations de la modelisation. Les resultats obtenus sont exploites par la suite dans la solution de l'assemblage de Hashin. Ainsi, plusieurs modeles micromecaniques classiques d'origines differentes se voient unifier et rattacher, dans ce travail, a la representation geometrique de Hashin. En plus de pouvoir apprecier completement la pertinence de l'approximation de chaque modele dans cette vision unique, l'extension correcte de ces modeles aux materiaux multiphasiques est rendue possible. Plusieurs modeles analytiques et explicites sont alors proposee suivant des solutions de differents ordres de l'assemblage de Hashin. L'un des modeles explicite apparait comme une correction directe du modele de Mori-Tanaka, dans les cas ou celui ci echoue a

Relation entre les caractéristiques des table-bancs et les mesures anthropométriques des écoliers au Benin

PubMed Central

Falola, Stève Marjelin; Gouthon, Polycarpe; Falola, Jean-Marie; Fiogbe, Michel Armand; Nigan, Issiako Bio

2014-01-01

Introduction Le mobilier scolaire et la posture assise en classe sont souvent impliqués dans l'apparition des douleurs rachidiennes, influant de fait sur la qualité des tâches réalisées par les apprenants. Aucune étude n'a encore vérifié le degré d'adéquation entre les caractéristiques du mobilier et celles des écoliers au Bénin. L'objectif de cette étude transversale est donc de déterminer la relation entre les dimensions des table-bancs utilisées en classe et les mesures anthropométriques des écoliers au Bénin. Methods Elle a été réalisée avec un échantillon probabiliste de 678 écoliers, âgés de 4 à 17 ans. Les mesures anthropométriques des écoliers et les mensurations relatives aux longueurs, largeurs et hauteurs des table-bancs ont été mesurées, puis intégrées aux équations proposées dans la littérature. Les pourcentages des valeurs situées hors des limitesacceptables, dérivées de l'application des équations ont été calculés. Results La largeur et la hauteur des table-bancs utilisées par les écoliers étaient plus élevées (p < 0,05) que les valeurs de référence recommandées par les structures officielles de contrôle et de production des mobiliers scolaires au Bénin. Quel que soit le sexe, il y avait une inadéquation entre la largeur du banc et la longueur fesse-poplité, puis entre la hauteur de la table et la distance coude-bancdes écoliers. Conclusion Les résultats suggèrent de prendre en compte l’évolution des mesures anthropométriques des écoliers dans la confection des table-bancs, afin de promouvoir de bonnes postures assises en classe et de réduire le risque de troubles du rachis. PMID:25317232

Muscle mass is associated with incident fracture in postmenopausal women: The OFELY study.

PubMed

Sornay-Rendu, E; Duboeuf, F; Boutroy, S; Chapurlat, R D

2017-01-01

The relationships between body composition and bone mineral density are well established but the contribution of body composition to the risk of fracture (Fx) has rarely been evaluated prospectively. We analyzed the risk of Fx by body composition in 595 postmenopausal women (mean age 66±8years) from a longitudinal cohort study (Os des Femmes de Lyon). We assessed the risk of the first incident fragility Fx according to body composition obtained from whole-body DXA: abdominal visceral (VFAT) and subcutaneous fat mass (SFAT), total body fat mass (FM), lean mass index (LMI) and appendicular skeletal muscle mass index (ASMI). During a median [IQ] follow-up of 13.1years [1.9], 138 women sustained a first incident Fx, including 85 women with a major osteoporotic Fx (MOP Fx: hip, clinical spine, humerus or wrist). After adjustment for age, women who sustained Fx had lower BMI (-4%, p=0.01), LMI (-6%, p=0.002) and ASMI (-3%, p=0.003), compared with women without Fx. After adjustment for age, prevalent Fx, physical activity, incident falls and FN BMD, each SD increase of baseline values of LMI and ASMI was associated with decreased Fx risk with adjusted hazard ratios of 0.76 for both of p≤0.02. Those associations were similar after accounting for the competing risk of death. VFAT and SFAT were associated with Fx risk in the multivariate model only for MOP Fx and the association did not persist after consideration of competing mortality. We conclude that lean mass and appendicular muscle mass indexes are associated with the risk of fracture in postmenopausal women independently of BMD and clinical risk factors. Copyright © 2016 Elsevier Inc. All rights reserved.

Profil épidémiologique des tumeurs malignes primitives des glandes salivaires : à propos de 154 cas

PubMed Central

Setti, Khadija; Mouanis, Mohamed; Moumni, Abdelmounim; Maher, Mostafa; Harmouch, Amal

2014-01-01

Introduction Les tumeurs des glandes salivaires sont des tumeurs rares représentant 3à 5% des tumeurs de la tête et du cou. La classification de l'OMS 2005 distingue les tumeurs épithéliales, les tumeurs mésenchymateuses, les tumeurs hématologiques et les tumeurs secondaires. Méthodes Notre travail consiste en une étude rétrospective réalisée sur une période de 10 ans allant de janvier 2002 à janvier 2012. Les critères d'inclusion étaient: l'âge, le sexe, le siège de la tumeur et le type histologique. Résultats L'incidence annuelle des tumeurs malignes primitives des glandes salivaires dans notre série était de 15 cas par an. Cent cinquante quatre cas de tumeurs malignes primitives des glandes salivaires ont été colligés sans prédominance de sexe (78 femmes (50,6%) et 76 hommes (49,4%)). La moyenne d'âge était de 60 ans avec des extrêmes de 4 et 83 ans et un pic de fréquence entre 51et 70 ans. Deux tiers des cas (65%) avaient une localisation au niveau des glandes principales avec 66 cas au niveau de la parotide (43%) et 34 cas au niveau de la glande sous maxillaire (22%). Cinquante quatre patients avaient une tumeur maligne des glandes salivaires accessoires (35%) dont 61% au niveau du palais. Aucun cas de tumeur maligne de la glande sublinguale n'a été recensé dans notre étude. Le type histologique prédominant dans notre série était le carcinome adénoïde kystique et retrouvé chez 43 patients (27,9%), suivi de l'adénocarcinome sans autre indication chez 37 patients (24%) puis du carcinome mucoépidermoïde chez 16 patients (10,4%) et de l'adénocarcinome polymorphe de bas grade également chez 16 patients (10. 4%). Conclusion Les tumeurs malignes des glandes salivaires représentent un ensemble hétérogène de maladies de caractérisation complexe et de fréquence variable. PMID:25120861

Using XML to encode TMA DES metadata.

PubMed

Lyttleton, Oliver; Wright, Alexander; Treanor, Darren; Lewis, Paul

2011-01-01

The Tissue Microarray Data Exchange Specification (TMA DES) is an XML specification for encoding TMA experiment data. While TMA DES data is encoded in XML, the files that describe its syntax, structure, and semantics are not. The DTD format is used to describe the syntax and structure of TMA DES, and the ISO 11179 format is used to define the semantics of TMA DES. However, XML Schema can be used in place of DTDs, and another XML encoded format, RDF, can be used in place of ISO 11179. Encoding all TMA DES data and metadata in XML would simplify the development and usage of programs which validate and parse TMA DES data. XML Schema has advantages over DTDs such as support for data types, and a more powerful means of specifying constraints on data values. An advantage of RDF encoded in XML over ISO 11179 is that XML defines rules for encoding data, whereas ISO 11179 does not. We created an XML Schema version of the TMA DES DTD. We wrote a program that converted ISO 11179 definitions to RDF encoded in XML, and used it to convert the TMA DES ISO 11179 definitions to RDF. We validated a sample TMA DES XML file that was supplied with the publication that originally specified TMA DES using our XML Schema. We successfully validated the RDF produced by our ISO 11179 converter with the W3C RDF validation service. All TMA DES data could be encoded using XML, which simplifies its processing. XML Schema allows datatypes and valid value ranges to be specified for CDEs, which enables a wider range of error checking to be performed using XML Schemas than could be performed using DTDs.

Using XML to encode TMA DES metadata

PubMed Central

Lyttleton, Oliver; Wright, Alexander; Treanor, Darren; Lewis, Paul

2011-01-01

Background: The Tissue Microarray Data Exchange Specification (TMA DES) is an XML specification for encoding TMA experiment data. While TMA DES data is encoded in XML, the files that describe its syntax, structure, and semantics are not. The DTD format is used to describe the syntax and structure of TMA DES, and the ISO 11179 format is used to define the semantics of TMA DES. However, XML Schema can be used in place of DTDs, and another XML encoded format, RDF, can be used in place of ISO 11179. Encoding all TMA DES data and metadata in XML would simplify the development and usage of programs which validate and parse TMA DES data. XML Schema has advantages over DTDs such as support for data types, and a more powerful means of specifying constraints on data values. An advantage of RDF encoded in XML over ISO 11179 is that XML defines rules for encoding data, whereas ISO 11179 does not. Materials and Methods: We created an XML Schema version of the TMA DES DTD. We wrote a program that converted ISO 11179 definitions to RDF encoded in XML, and used it to convert the TMA DES ISO 11179 definitions to RDF. Results: We validated a sample TMA DES XML file that was supplied with the publication that originally specified TMA DES using our XML Schema. We successfully validated the RDF produced by our ISO 11179 converter with the W3C RDF validation service. Conclusions: All TMA DES data could be encoded using XML, which simplifies its processing. XML Schema allows datatypes and valid value ranges to be specified for CDEs, which enables a wider range of error checking to be performed using XML Schemas than could be performed using DTDs. PMID:21969921

Les soins aux enfants et aux adolescents des familles des militaires canadiens : les considérations particulières

PubMed Central

Rowan-Legg, Anne

2017-01-01

Résumé Les familles des militaires font face à de nombreux facteurs de stress, tels que les réinstallations fréquentes, les longues pério des de séparation familiale, l’isolement géographique du réseau de soutien de la famille élargie et le déploiement en zones très dangereuses. Les enfants et les adolescents des familles des militaires vivent les mêmes trajectoires développementales et motivationnelles que leurs homologues civils, mais ils sont également aux prises avec des pressions et des facteurs de stress liés à leur développement qui sont inhabituels et qui leur sont imposés par les exigences de la vie militaire. Les effets de la vie militaire sur les familles et les enfants commencent à être admis et mieux caractérisés. Il est essentiel de comprendre les préoccupations propres aux enfants et aux adolescents des familles des militaires et de mobiliser les ressources nécessaires pour les soutenir afin de répondre à leurs besoins en matière de santé.

Lignes directrices canadiennes sur l’utilisation sécuritaire et efficace des opioïdes pour la douleur chronique non cancéreuse

PubMed Central

Kahan, Meldon; Wilson, Lynn; Mailis-Gagnon, Angela; Srivastava, Anita

2011-01-01

Résumé Objectif Présenter aux médecins de famille un résumé clinique pratique sur la prescription d’opioïdes à des populations particulières en se fondant sur les recommandations faites dans les lignes directrices canadiennes sur l’utilisation sécuritaire et efficace des opioïdes pour la douleur chronique non cancéreuse. Qualité des données Pour produire les lignes directrices, les chercheurs ont effectué une synthèse critique de la littérature médicale en insistant plus précisément sur les études de l’efficacité et de la sécurité des opioïdes dans des populations particulières. Message principal Les médecins de famille peuvent atténuer les risques de surdose, de sédation, d’usage abusif et de dépendance grâce à des stratégies adaptées à l’âge et à l’état de santé des patients. Dans le cas de patients à risque de dépendance, on devrait réserver les opioïdes aux douleurs nociceptives ou neuropathiques bien définies qui n’ont pas répondu aux traitements de première intention. Il faut procéder lentement au titrage des opioïdes, avec des dispensations fréquentes et une étroite surveillance pour dépister tout signe d’usage abusif. Une dépendance aux opioïdes suspectée est prise en charge au moyen d’une thérapie structurée aux opioïdes, d’un traitement à la méthadone ou à la buprénorphine ou encore d’un traitement fondé sur l’abstinence. Les patients souffrant de troubles de l’humeur ou d’anxiété ont tendance à avoir une réponse analgésique atténuée aux opioïdes, sont à risque plus élevé d’usage abusif et prennent souvent des sédatifs qui interagissent défavorablement avec les opioïdes. Il faut prendre des précautions semblables à celles utilisées avec d’autres patients à risque élevé. Il faut faire un sevrage progressif si la douleur du patient demeure sévère même avec un essai adéquat de thérapie aux opioïdes. Chez les personnes âgées, la s

L'astronomie des Anciens

NASA Astrophysics Data System (ADS)

Nazé, Yaël

2009-04-01

Quelle que soit la civilisation à laquelle il appartient, l'être humain cherche dans le ciel des réponses aux questions qu'il se pose sur son origine, son avenir et sa finalité. Le premier mérite de ce livre est de nous rappeler que l'astronomie a commencé ainsi à travers les mythes célestes imaginés par les Anciens pour expliquer l'ordre du monde et la place qu'ils y occupaient. Mais les savoirs astronomiques passés étaient loin d'être négligeables et certainement pas limités aux seuls travaux des Grecs : c'est ce que l'auteur montre à travers une passionnante enquête, de Stonehenge à Gizeh en passant par Pékin et Mexico, fondée sur l'étude des monuments anciens et des sources écrites encore accessibles. Les tablettes mésopotamiennes, les annales chinoises, les chroniques médiévales, etc. sont en outre d'une singulière utilité pour les astronomes modernes : comment sinon remonter aux variations de la durée du jour au cours des siècles, ou percer la nature de l'explosion qui a frappé tant d'observateurs en 1054 ? Ce livre offre un voyage magnifiquement illustré à travers les âges, entre astronomie et archéologie.

KSC-07pd3599

NASA Image and Video Library

2007-12-09

KENNEDY SPACE CENTER, FLA. -- Doug Lyons, STS-122 launch director, participates in a news briefing following the conclusion of a Mission Management Team, or MMT, meeting. The meeting followed the morning's launch scrub of the space shuttle Atlantis STS-122 mission caused by problems experienced with the external tank's engine cutoff sensor system during tanking for the second launch attempt. An announcement was made during the briefing that the STS-122 launch is postponed to no earlier than Jan. 2, 2008, to give the team time to resolve the system's problems. Atlantis will carry the Columbus Laboratory, the European Space Agency's largest contribution to the construction of the International Space Station. It will support scientific and technological research in a microgravity environment. Permanently attached to the Harmony node of the space station, the laboratory will carry out experiments in materials science, fluid physics and biosciences, as well as perform a number of technological applications. Photo credit: NASA/Kim Shiflett

Pregnancy outcome after risk assessment of occupational exposure to organic solvents: a prospective cohort study.

PubMed

Testud, François; D'Amico, Andrea; Lambert-Chhum, Rachel; Garayt, Christelle; Descotes, Jacques

2010-11-01

A rational medical, occupational and toxicological approach is instrumental to select objectively among pregnant women exposed to chemicals at the workplace those who should be withdrawn or benefit from improvements of working conditions. Risk assessment is based on a comprehensive review of compounds' hazards and a thorough evaluation of the actual exposure including biomonitoring whenever as possible. Since 1996, the Lyon Poison Center has been conducting a prospective follow-up of pregnant women exposed to chemicals at the workplace. Of these, 206 exposed to organic solvents since conception were selected and matched with 206 exposed to a non-embryotoxic agent. Total withdrawal from the workplace was recommended in 22% of cases, but exposure was not considered to be hazardous to pregnancy in 51%. Overall, no increase in adverse outcomes was found. Maintaining pregnant women at their workplace, particularly most of the laboratory technicians, is reasonably possible after careful toxicological risk assessment. Copyright © 2010 Elsevier Inc. All rights reserved.

KSC Center Director Bridges accepts an ISO 9001 certificate from DNV

NASA Technical Reports Server (NTRS)

1998-01-01

Center Director Roy Bridges displays the ISO 9001 certificate he was awarded by Det Norske Veritas (DNV), Inc., an international ISO certification organization, at a ceremony at KSC. Dalton Lyon of DNV made the presentation, which included a 2000th ISO Certificate Plaque. ISO 9001 comprises the most detailed, comprehensive set of standard requirements for quality programs established by the International Standards Organization. The presentation followed a successful independent audit by DNV of the KSC Management System in May of this year. The third-party auditors examined about 20 elements of KSC's system, including management responsibility, design control, documentation, test and inspection, and corrective action procedures. DNV found that KSC met or exceeded the stringent quality standards in all areas. KSC will use this certification as a tool to improve an already world-class team. All NASA centers are required by NASA Administrator Daniel S. Goldin to be ISO 9001 registered by September 1999. NASA is the first federal agency to seek the quality certification.

Charge Exchange of Ne^9+ for X-ray Emission

NASA Astrophysics Data System (ADS)

Lyons, David

2016-01-01

Using the molecular-orbital close-coupling (MOCC) method, single electron capture (SEC) cross sections were computed for Ne^9+ colliding with H.Potential energies and nonadiabatic couplings were calculated and used to obtain the MOCC cross sections which are final-quantum-state-resolved including a separation of singlet and triplet states. Atomic-orbital close-coupling, classical trajectory Monte Carlo, and multichannel Landau-Zener (MCLZ) calculations are also performed. Cross sections for more complicated targets including He, H2, N2, H2O, CO, and CO2, were obtained with the MCLZ method. The SEC results are compared with experimental and other theoretical data, where available. The SEC cross sections are being used in cascade models to predict X-ray emission spectra relevant to solar systemand astrophysical environments.D. Lyons, R. S. Cumbee, P. D. Mullen, P. C. Stancil (UGA), D. R. Schultz (UNT), P. Liebermann (Wuppertal Univ.),R. Buenker (NCSU).This work was partially supported by NASA grant NNX09AC46G.

PCR and ELISA (VIDAS ECO O157®) Escherichia coli O157:H7 identification in Minas Frescal cheese commercialized in Goiânia, GO

PubMed Central

Carvalho, Rosangela Nunes; de Oliveira, Antonio Nonato; de Mesquita, Albenones José; Minafra e Rezende, Cíntia Silva; de Mesquita, Adriano Queiroz; Romero, Rolando Alfredo Mazzoni

2014-01-01

Escherichia coli O157:H7 has been incriminated in food poisoning outbreaks and sporadic cases of hemorrhagic colitis and hemolytic uremic syndrome in many countries. Considering the high susceptibility of Minas Frescal cheese to contamination by E. coli O157:H7, the aim of this study was to determine the occurrence of this pathogen through PCR (Polymerase Chain Reaction) and ELISA (VIDAS ECO O157®, bioMérieux, Lyon, France) test. Thirty cheese samples manufactured by artisan farmhouse producers were collected from open-air markets in Goiânia and thirty from industries under Federal Inspection located in Goiás State which trade their products in supermarkets in Goiânia. E. coli O157:H7 was detected in 6.67% samples collected in open air markets using ELISA, and 23,33% with PCR. The pathogen was not detected in samples from industries under Federal Inspection. PMID:24948907

Premiers résultats du réseau sismique (CRLN) de la partie ouest du rift de Corinthe : évidence de la réactivation d'une ancienne faille

NASA Astrophysics Data System (ADS)

Lyon-Caen, Hélène; Papadimitriou, Panayotis; Deschamps, Anne; Bernard, Pascal; Makropoulos, Kostas; Pacchiani, Francesco; Patau, Geneviève

2004-03-01

The 12 stations Corinth Rift Laboratory Seismological Network (CRLNET) aims at monitoring the seismicity ( Ml>1) in the CRL area and at constraining the geometry of active structures at depth. Two years of microseismicity (2000-2001) recorded by the CRLNET in the Aigion area shows: (1) background seismicity inside the Corinth rift at depth of 4.5-11 km, deepening towards the north and no activity in the upper 4 km of the crust - this seismicity is not clearly related to major faults observed at the surface -; (2) a swarm, 6 km south of the city of Aigion, associated with the Mw=4.2, 8 April 2001 earthquake. This earthquake occurred at 6 km depth, on a SW-NE oriented fault dipping 40° to the northwest and corresponds to normal faulting with a right lateral component of slip. It likely occurred on an old structure reactivated in the present stress field. To cite this article: H. Lyon-Caen et al., C. R. Geoscience 336 (2004).

Early Renal Involvement in a Girl with Classic Fabry Disease.

PubMed

Perretta, Fernando; Antongiovanni, Norberto; Jaurretche, Sebastián

2017-01-01

Fabry disease is an X-linked lysosomal storage disorder resulting from the deficiency or absence of the enzyme alpha galactosidase A; this defect leads to the systemic accumulation of globotriaosylceramide and its metabolites. Organic involvement in men is well known, but in women it is controversial, mainly due to the random X-chromosome inactivation in each of their cells (Lyon hypothesis). This would explain why women (heterozygotes) present a wide variability in the severity of their phenotype. The manifestations are multisystemic and begin in early childhood, reaching a severe compromise in adulthood. Typical acroparesthesia in hands and feet, gastrointestinal symptoms, angiokeratomas, dyshidrosis, hearing loss, arrhythmias, hypertrophic cardiomyopathy, cerebrovascular accidents, and renal failure can be observed. Nephropathy is one of the major complications of Fabry disease. Glomerular and vascular changes are present before progression to overt proteinuria and decreased glomerular filtration rate, even in pediatric patients. A case of incipient renal involvement in a girl with classic Fabry disease is reported.

The History of Otolaryngology In New Orleans.

PubMed

Lyons, George D

2016-01-01

George D. Lyons, MD, now becoming "an elder statesman," he decided summarize the early history of otolaryngology as it developed in New Orleans. Francis LeJeune, MD, Sr., a much admired and loved otolaryngologist, has afforded a great insight through his memoirs in the early development of our specialty in his report of Otolaryngology in the South. Dr. LeJune, Sr. began his brief paper just before his death. Excerpts from this paper have been used by the American Laryngological Association. There will be no bibliography. Most of this information was obtained from Dr. LeJeune's memoirs, history departments of the Academy, Touro Infirmary, Eye, Ear, Nose, and Throat (EENT) archives and interviews with descendants of our early leaders. A special thanks to them for their time, research, and generosity of information. There has been some debate regarding the precision of some of the dates, but they are as chronologically accurate as possible.

Indications and interpretation of esophageal function testing.

PubMed

Gyawali, C Prakash; de Bortoli, Nicola; Clarke, John; Marinelli, Carla; Tolone, Salvatore; Roman, Sabine; Savarino, Edoardo

2018-05-12

Esophageal symptoms are common, and can arise from mucosal, motor, functional, and neoplastic processes, among others. Judicious use of diagnostic testing can help define the etiology of symptoms and can direct management. Endoscopy, esophageal high-resolution manometry (HRM), ambulatory pH or pH-impedance manometry, and barium radiography are commonly used for esophageal function testing; functional lumen imaging probe is an emerging option. Recent consensus guidelines have provided direction in using test findings toward defining mechanisms of esophageal symptoms. The Chicago Classification describes hierarchical steps in diagnosing esophageal motility disorders. The Lyon Consensus characterizes conclusive evidence on esophageal testing for a diagnosis of gastroesophageal reflux disease (GERD), and establishes a motor classification of GERD. Taking these recent advances into consideration, our discussion focuses primarily on the indications, technique, equipment, and interpretation of esophageal HRM and ambulatory reflux monitoring in the evaluation of esophageal symptoms, and describes indications for alternative esophageal tests. © 2018 New York Academy of Sciences.

Speckle interferometry. Data acquisition and control for the SPID instrument.

NASA Astrophysics Data System (ADS)

Altarac, S.; Tallon, M.; Thiebaut, E.; Foy, R.

1998-08-01

SPID (SPeckle Imaging by Deconvolution) is a new speckle camera currently under construction at CRAL-Observatoire de Lyon. Its high spectral resolution and high image restoration capabilities open new astrophysical programs. The instrument SPID is composed of four main optical modules which are fully automated and computer controlled by a software written in Tcl/Tk/Tix and C. This software provides an intelligent assistance to the user by choosing observational parameters as a function of atmospheric parameters, computed in real time, and the desired restored image quality. Data acquisition is made by a photon-counting detector (CP40). A VME-based computer under OS9 controls the detector and stocks the data. The intelligent system runs under Linux on a PC. A slave PC under DOS commands the motors. These 3 computers communicate through an Ethernet network. SPID can be considered as a precursor for VLT's (Very Large Telescope, four 8-meter telescopes currently built in Chile by European Southern Observatory) very high spatial resolution camera.

The European network of Biosafety-Level-4 laboratories: enhancing European preparedness for new health threats.

PubMed

Nisii, C; Castilletti, C; Di Caro, A; Capobianchi, M R; Brown, D; Lloyd, G; Gunther, S; Lundkvist, A; Pletschette, M; Ippolito, G

2009-08-01

Emerging and re-emerging infections and possible bioterrorism acts will continue to challenge both the medical community and civilian populations worldwide, urging health authorities to respond rapidly and effectively. Established in 2005, the European Community (EC)-funded European Network of Biosafety-Level-4 laboratories (Euronet-P4), which brings together the laboratories in Porton Down, London, Hamburg, Marburg, Solna, Lyon and Rome, seeks to increase international collaboration in the areas of high containment laboratory biosafety and viral diagnostic capability, to strengthen Europe's capacity to respond to an infectious disease emergency, and to offer assistance to countries not equipped with such costly facilities. Network partners have agreed on a common strategy to fill the gaps identified in the field of risk group-4 agents' laboratory diagnosis, namely the lack of standardization and of reference samples. The network has received a further 3-year funding, to offer assistance to external laboratories, and to start the planning of field activities.

Alexis Carrel: genius, innovator and ideologist.

PubMed

Dutkowski, P; de Rougemont, O; Clavien, P-A

2008-10-01

Alexis Carrel was a Frenchman from Lyon, who gained fame at the Rockefeller Institute in New York at the beginning of the 20th century. He was the first to demonstrate that arteriovenous anastomoses were possible. Alexis Carrel was awarded the Nobel Prize for his contributions to vascular surgery and transplantation in 1912. He was a versatile scientist, who made numerous discoveries from the design of an antiseptic solution to treat injuries during the First World War to tissue culture and engineering, and organ preservation, making him the father of solid organ transplantation. Together, with the famous aviator and engineer Charles Lindbergh, they were the first scientists capable of keeping an entire organ alive outside of the body, using a perfusion machine. Due to his many dubious ideas and his association with fascism in the 1930s and during the Second World War, many of his scientific achievements have been forgotten today and taken for granted.

KSC-98pc907

NASA Image and Video Library

1998-08-11

Center Director Roy Bridges displays the ISO 9001 certificate he was awarded by Det Norske Veritas (DNV), Inc., an international ISO certification organization, at a ceremony at KSC. Dalton Lyon of DNV made the presentation, which included a 2000th ISO Certificate Plaque. ISO 9001 comprises the most detailed, comprehensive set of standard requirements for quality programs established by the International Standards Organization. The presentation followed a successful independent audit by DNV of the KSC Management System in May of this year. The third-party auditors examined about 20 elements of KSC's system, including management responsibility, design control, documentation, test and inspection, and corrective action procedures. DNV found that KSC met or exceeded the stringent quality standards in all areas. KSC will use this certification as a tool to improve an already world-class team. All NASA centers are required by NASA Administrator Daniel S. Goldin to be ISO 9001 registered by September 1999. NASA is the first federal agency to seek the quality certification

Mineral dust photochemistry induces nucleation events in the presence of SO2

PubMed Central

Dupart, Yoan; King, Stephanie M.; Nekat, Bettina; Nowak, Andreas; Wiedensohler, Alfred; Herrmann, Hartmut; David, Gregory; Thomas, Benjamin; Miffre, Alain; Rairoux, Patrick; D’Anna, Barbara; George, Christian

2012-01-01

Large quantities of mineral dust particles are frequently ejected into the atmosphere through the action of wind. The surface of dust particles acts as a sink for many gases, such as sulfur dioxide. It is well known that under most conditions, sulfur dioxide reacts on dust particle surfaces, leading to the production of sulfate ions. In this report, for specific atmospheric conditions, we provide evidence for an alternate pathway in which a series of reactions under solar UV light produces first gaseous sulfuric acid as an intermediate product before surface-bound sulfate. Metal oxides present in mineral dust act as atmospheric photocatalysts promoting the formation of gaseous OH radicals, which initiate the conversion of SO2 to H2SO4 in the vicinity of dust particles. Under low dust conditions, this process may lead to nucleation events in the atmosphere. The laboratory findings are supported by recent field observations near Beijing, China, and Lyon, France. PMID:23213230

MyLabStocks: a web-application to manage molecular biology materials

PubMed Central

Chuffart, Florent; Yvert, Gaël

2014-01-01

Laboratory stocks are the hardware of research. They must be stored and managed with mimimum loss of material and information. Plasmids, oligonucleotides and strains are regularly exchanged between collaborators within and between laboratories. Managing and sharing information about every item is crucial for retrieval of reagents, for planning experiments and for reproducing past experimental results. We have developed a web-based application to manage stocks commonly used in a molecular biology laboratory. Its functionalities include user-defined privileges, visualization of plasmid maps directly from their sequence and the capacity to search items from fields of annotation or directly from a query sequence using BLAST. It is designed to handle records of plasmids, oligonucleotides, yeast strains, antibodies, pipettes and notebooks. Based on PHP/MySQL, it can easily be extended to handle other types of stocks and it can be installed on any server architecture. MyLabStocks is freely available from: https://forge.cbp.ens-lyon.fr/redmine/projects/mylabstocks under an open source licence. PMID:24643870

Epigenetic regulation in gallbladder cancer: Promoter methylation profiling as emergent novel biomarkers.

PubMed

Tekcham, Dinesh Singh; Tiwari, Pramod Kumar

2016-12-01

DNA methylation, once considered to rule the sex determination in Mary Lyon's hypothesis, has now reached the epicenter of human diseases, from monogenic (e.g. Prader Willi syndrome, Angelman syndromes and Beckwith-Wiedemann syndrome) to polygenic diseases, like cancer. Technological developments from gold standard to high throughput technologies have made tremendous advancement to define the epigenetic mechanism of cancer. Gallbladder cancer (GBC) is a fatal health issue affecting mostly the middle-aged women, whose survival rate is very low due to late symptomatic diagnosis. DNA methylation has become one of the key molecular mechanisms in the tumorigenesis of gallbladder. Various molecules have been reported to be epigenetically altered in GBC. In this review, we have discussed the classes of epigenetics, an overview of DNA methylation, technological approaches for its study, profile of methylated genes, their likely roles in GBC, future prospects of biomarker development and other discovery approaches, including therapeutics. © 2016 John Wiley & Sons Australia, Ltd.

Implementation Cryptography Data Encryption Standard (DES) and Triple Data Encryption Standard (3DES) Method in Communication System Based Near Field Communication (NFC)

NASA Astrophysics Data System (ADS)

Ratnadewi; Pramono Adhie, Roy; Hutama, Yonatan; Saleh Ahmar, A.; Setiawan, M. I.

2018-01-01

Cryptography is a method used to create secure communication by manipulating sent messages during the communication occurred so only intended party that can know the content of that messages. Some of the most commonly used cryptography methods to protect sent messages, especially in the form of text, are DES and 3DES cryptography method. This research will explain the DES and 3DES cryptography method and its use for stored data security in smart cards that working in the NFC-based communication system. Several things that will be explained in this research is the ways of working of DES and 3DES cryptography method in doing the protection process of a data and software engineering through the creation of application using C++ programming language to realize and test the performance of DES and 3DES cryptography method in encrypted data writing process to smart cards and decrypted data reading process from smart cards. The execution time of the entering and the reading process data using a smart card DES cryptography method is faster than using 3DES cryptography.

Relations de Dispersion et Diffusion des Glueballs et des Mesons dans la Theorie de Jauge U(1)(2+1) Compacte

NASA Astrophysics Data System (ADS)

Ahmed, Chaara El Mouez

Nous avons etudie les relations de dispersion et la diffusion des glueballs et des mesons dans le modele U(1)_{2+1} compact. Ce modele a ete souvent utilise comme un simple modele de la chromodynamique quantique (QCD), parce qu'il possede le confinement ainsi que les etats de glueballs. Par contre, sa structure mathematique est beaucoup plus simple que la QCD. Notre methode consiste a diagonaliser l'Hamiltonien de ce modele dans une base appropriee de graphes et sur reseau impulsion, afin de generer les relations de dispersion des glueballs et des mesons. Pour la diffusion, nous avons utilise la methode dependante du temps pour calculer la matrice S et la section efficace de diffusion des glueballs et des mesons. Les divers resultats obtenus semblent etre en accord avec les travaux anterieurs de Hakim, Alessandrini et al., Irving et al., qui eux, utilisent plutot la theorie des perturbations en couplage fort, et travaillent sur un reseau espace-temps.

Evaluation d’une grille de supervision des laboratoires des leishmanioses cutanées au Maroc

PubMed Central

El Mansouri, Bouchra; Amarir, Fatima; Hajli, Yamina; Fellah, Hajiba; Sebti, Faiza; Delouane, Bouchra; Sadak, Abderrahim; Adlaoui, El Bachir; Rhajaoui, Mohammed

2017-01-01

Introduction Afin d’évaluer une grille de contrôle standardisée de laboratoire de diagnostic des leishmanioses, comme nouveau outil de supervision. Méthodes Un essai pilote a été pratiqué sur sept laboratoires provinciaux, appartenant à quatre provinces au Maroc, en suivant l’évolution de leurs performances tous les deux ans, entre l’année 2006 et 2014. Cette étude détaille la situation des laboratoires provinciaux avant et après la mise en œuvre de la grille de supervision. Au total vingt et une grille sont analysées. Résultats En 2006, les résultats ont montré clairement une insuffisance des performances des laboratoires: besoin en formation (41.6%), personnel pratiquant le prélèvement cutané (25%), pénurie en matériels et réactifs (65%), gestions documentaire et local non conformes (85%). Différentes actions correctives ont été menées par le Laboratoire National de Référence des Leishmanioses (LNRL) durant la période d’étude. En 2014, le LNRL a enregistré une nette amélioration des performances des laboratoires. Les besoins en matière de formation, qualité du prélèvement, dotation en matériels et réactifs ont été comblés et une coordination efficace s’est établie entre le LNRL et les laboratoires provinciaux. Conclusion Ceci montre l'efficacité de la grille comme outil de supervision de grande qualité, et comme pierre angulaire de tout progrès qui doit être obtenu dans les programmes de lutte contre les leishmanioses. PMID:29187922

Identification et prise en charge des femmes ayant des antécédents familiaux de cancer du sein

PubMed Central

Heisey, Ruth; Carroll, June C.

2016-01-01

Résumé Objectif Résumer les meilleures données portant sur les stratégies d’identification et de prise en charge des femmes qui présentent des antécédents familiaux de cancer du sein. Sources d’information Une recherche a été effectuée sur PubMed à l’aide des mots-clés anglais suivants : breast cancer, guidelines, risk, family history, management et magnetic resonance imaging screening, entre 2000 et 2016. La plupart des données sont de niveau II. Message principal Une bonne anamnèse familiale est essentielle lors de l’évaluation du risque de cancer du sein afin d’identifier les femmes qui sont candidates à une recommandation en counseling génétique pour un éventuel test génétique. On peut sauver des vies en offrant aux femmes porteuses d’une mutation au gène BRCA des interventions chirurgicales de réduction des risques (mastectomie bilatérale prophylactique, salpingo-ovariectomie bilatérale). Il faut encourager toutes les femmes qui présentent des antécédents familiaux de cancer du sein à demeurer actives et à limiter leur consommation d’alcool à moins de 1 verre par jour; certaines femmes sont admissibles à la chimioprévention. Il faut offrir aux femmes dont le risque à vie de cancer du sein est de 20 à 25 % ou plus un dépistage poussé par imagerie par résonance magnétique en plus d’une mammographie. Conclusion Une vie saine et la chimioprévention (chez les candidates) pourraient réduire l’incidence du cancer du sein; le dépistage poussé pourrait entraîner une détection plus précoce. Le fait d’aiguiller des femmes porteuses d’une mutation au BRCA vers la chirurgie de réduction des risques sauve des vies. PMID:27737991

Note des Éditeurs scientifiques

NASA Astrophysics Data System (ADS)

Averbuch, P.

Cette série d'articles est une revue de résultats expérimentaux sur différents "fluides" moléculaires, dans lesquels la cohésion est due à des forces de Van der Waals et à des liaisons hydrogène, l'eau étant un de ces fluides. Ces résultats sont présentés de façon à justifier expérimentalement un modèle original, non extensif, des propriétés de ces fluides, et l'ensemble se présente sous la forme de trois articles décrivant le modèle, suivis chacun par un article le comparant aux résultats expérimentaux publiés par de nombreux auteurs. Le caractère non extensif des propriétés physiques des fluides est choquant, contraire à beaucoup d'idées établies, il semble n'avoir en sa faveur qu'un argument, la comparaison avec un nombre de résultats expérimentaux assez grand pour que l'effet du hasard soit difficilement soupçonnable. En particulier, les écarts entre des résultats de mesures faits par des auteurs différents dans des conditions différentes sont expliqués, le sérieux et la compétence des différents expérimentateurs ne sont plus mis en doute : mais l'interprétation de ces résultats avec un modèle extensif non adapté est seule mise en cause. Les modèles extensifs étant utilisés systématiquement, au delà des expériences de physiciens, dans les calculs d'ingénieurs, et dans la modélisation d'appareils qui fonctionnent et de phénomènes naturels observés par tout le monde, il fallait expliquer pourquoi on pouvait renoncer à l'extensivité. Les raisons du succès pratique des modèles extensifs sont données, d'abord dans le cas des nématiques, puis dans celui des liquides ordinaires, et c'est ce qui rend l'ensemble cohérent, tant avec les mesures physiques fines qu'avec les observations quotidiennes. Il n'en reste pas moins que si l'interprétation donnée dans cette série d'articles est généralisable, une justification théorique du modèle utilisé devient nécessaire. Pour ce qui est des propriétés d

Applications of Composite Materials in Helicopter Construction (Les Applications des Materiaux Composite dans la Construction des Helicopteres),

DTIC Science & Technology

1983-11-21

TRANSLATION TITLE: APPLICATIONS OF COMPOSITE MATERIALS IN HELICOPTER CONSTRUCTION LES APPLICATIONS DES MATERTAUX COMWSITE DANS LA CONSTRUCTION DES...International Symposium on Design and Use of Kevlar in Aircraft, Geneva, 12 October 1982 [Beziac, Gilbert;* Les applications des mat6riaux composite...the pilot’s orders to the engine and the rotors. --Rear rotor Conventional or "faired propeller" type with its overall pitch control --Vibration

Cemex, Inc., (Colorado) Lyons Cemex Plant Title V Operating Permit,Order Partially Denying and Partially Granting Petition for Objection to Permit

EPA Pesticide Factsheets

This document may be of assistance in applying the Title V air operating permit regulations. This document is part of the Title V Petition Database available at www2.epa.gov/title-v-operating-permits/title-v-petition-database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

[Proper use of fluoroquinolones in hospitalized elderly patients: Realisation of a clinical audit in geriatric hospitals of Lyon University Hospital].

PubMed

Papailhau, C; Gaujard, S; Girard, R; Bourguignon, L; Mouchoux, C

2018-05-18

Fluoroquinolones (FQ) are widely used because of their broad spectrum and their ease of use, especially in the elderly. Nevertheless, their misuse is behind the development and the emergence of bacterial resistances. The objective of this study was to evaluate the compliance of FQ prescriptions in the elderly hospitalized, before and after pharmaceutical interventions (PI). A prospective clinical audit was conducted for three months in three geriatric hospitals. A pharmacist carried out the evaluation of the prescription's conformity with the help of referent geriatric doctor in infectiology according to the criteria defined by SPILF recommendations (2015). The PIs and their future have been collected and codified. A total of 100 patients were included (mean age: 85.3 years; male female ratio: 1,17). The medical-pharmaceutical collaboration helped to increase the overall compliance rate from 56 to 80%. FQ were used for urinary (72%) or respiratory (20%) infections, first-line (57%), documented (60%) and monotherapy (63%). Our results show that FQ misuse is a not inconsiderable case since in 28% they should not have been prescribed. Thirty-three PI were performed and accepted in 72% cases. Actions to promote the FQ proper use have therefore been put in place: communication of the audit results, dissemination of a summary of SPILF recommendations and creation of a tool to assist in the analysis of prescriptions FQ for pharmacists. Copyright © 2018. Published by Elsevier SAS.

Etude spectroscopique des collisions moleculaires (hydrogene-azote et hydrogene-oxygene) a des energies de quelques MeV

NASA Astrophysics Data System (ADS)

Plante, Jacinthe

1998-09-01

Les resultats presentes ici proviennent d'une etude systematique portant sur les collisions a vitesse constante, entre les projectiles d'hydrogene (H+, H2+ et H3+ a 1 MeV/nucleon) et deux cibles gazeuses (N2 et O2), soumises a differentes pressions. Les collisions sont analysees a l'aide des spectres d'emission (de 400 A a 6650 A) et des graphiques intensite/pression. Les spectres ont revele la presence des raies d'azote atomique, d'azote moleculaire, d'oxygene atomique, d'oxygene moleculaire et d'hydrogene atomique. Les raies d'hydrogene sont observees seulement avec les projectiles H2+ et H3+. Donc les processus responsables de la formation de ces raies sont des mecanismes de fragmentation des projectiles. Pour conclure, il existe une difference notable entre les projectiles et les differentes pressions. Les raies d'azote et d'oxygene augmentent selon la pression et les raies d'hydrogene atomique presentent une relation non lineaire avec la pression.

DES Science Portal: II- Creating Science-Ready Catalogs

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fausti Neto, Angelo; et al.

We present a novel approach for creating science-ready catalogs through a software infrastructure developed for the Dark Energy Survey (DES). We integrate the data products released by the DES Data Management and additional products created by the DES collaboration in an environment known as DES Science Portal. Each step involved in the creation of a science-ready catalog is recorded in a relational database and can be recovered at any time. We describe how the DES Science Portal automates the creation and characterization of lightweight catalogs for DES Year 1 Annual Release, and show its flexibility in creating multiple catalogs withmore » different inputs and configurations. Finally, we discuss the advantages of this infrastructure for large surveys such as DES and the Large Synoptic Survey Telescope. The capability of creating science-ready catalogs efficiently and with full control of the inputs and configurations used is an important asset for supporting science analysis using data from large astronomical surveys.« less

Using the verona coding definitions of emotional sequences (VR-CoDES) and health provider responses (VR-CoDES-P) in the dental context.

PubMed

Wright, Alice; Humphris, Gerry; Wanyonyi, Kristina L; Freeman, Ruth

2012-10-01

To show if cues, concerns and provider responses (defined in VR-CoDES and VR-CoDES-P manuals) are present, can be reliably coded and require additional advice for adoption in a dental context. Thirteen patients in a dental practice setting were videoed with either their dentist or hygienist and dental nurse present in routine treatment sessions. All utterances were coded using the Verona systems: VR-CoDES and the VR-CoDES-P. Rates of cue, concerns and provider responses described and reliability tested. The VR-CoDES and VR-CoDES-P were successfully applied in the dental context. The intra-rater ICCs for the detection of cues and concerns and provider response were acceptable and above 0.75. A similar satisfactory result was found for the inter-rater reliability. The VR-CoDES and the VR-CoDES-P are applicable in the dental setting with minor supporting guidelines and show evidence of reliable coding. The VR-CoDES and the VR-CoDES-P may be helpful tools for analysing patient cues and concerns and the dental professionals' responses in the dental context. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

Reticulation des fibres lignocellulosiques

NASA Astrophysics Data System (ADS)

Landrevy, Christel

Pour faire face à la crise économique la conception de papier à valeur ajoutée est développée par les industries papetières. Le but de se projet est l'amélioration des techniques actuelles de réticulation des fibres lignocellulosiques de la pâte à papier visant à produire un papier plus résistant. En effet, lors des réactions de réticulation traditionnelles, de nombreuses liaisons intra-fibres se forment ce qui affecte négativement l'amélioration anticipée des propriétés physiques du papier ou du matériau produit. Pour éviter la formation de ces liaisons intra-fibres, un greffage sur les fibres de groupements ne pouvant pas réagir entre eux est nécessaire. La réticulation des fibres par une réaction de « click chemistry » appelée cycloaddition de Huisgen entre un azide et un alcyne vrai, catalysée par du cuivre (CuAAC) a été l'une des solutions trouvée pour remédier à ce problème. De plus, une adaptation de cette réaction en milieux aqueux pourrait favoriser son utilisation en milieu industriel. L'étude que nous désirons entreprendre lors de ce projet vise à optimiser la réaction de CuAAC et les réactions intermédiaires (propargylation, tosylation et azidation) sur la pâte kraft, en milieu aqueux. Pour cela, les réactions ont été adaptées en milieu aqueux sur la cellulose microcristalline afin de vérifier sa faisabilité, puis transférée à la pâte kraft et l'influence de différents paramètres comme le temps de réaction ou la quantité de réactifs utilisée a été étudiée. Dans un second temps, une étude des différentes propriétés conférées au papier par les réactions a été réalisée à partir d'une série de tests papetiers optiques et physiques. Mots Clés Click chemistry, Huisgen, CuAAC, propargylation, tosylation, azidation, cellulose, pâte kraft, milieu aqueux, papier.

Minimisation des inductances propres des condensateurs à film métallisé

NASA Astrophysics Data System (ADS)

Joubert, Ch.; Rojat, G.; Béroual, A.

1995-07-01

In this article, we examine the different factors responsible for the equivalent series inductance in metallized capacitors and we propose structures for capacitors that reduce this inductance. After recalling the structure of metallized capacitors we compare, by experimental measurements, the inductance due to the winding and that one added by the connections. The latter can become preponderant. In order to explain the experimental evolution of the winding impedance vs. frequency, we describe an analytical model which gives the current density in the winding and its impedance. This model enables us to determine the self resonant frequency for different types of capacitors. From where, we can infer the influence of the height of capacitors and their internal and external radius upon performances, It appears that to reduce the equivalent series inductance, it is better to use flat windings and annular windings. Dans cet article nous examinons les différents facteurs responsables de l'inductance équivalente série dans les condensateurs à film métallisé et proposons des géométries de condensateurs qui réduisent cette inductance. Après avoir rappelé la structure des condensateurs à film métallisé, nous comparons, par des mesures expérimentales, l'inductance due au bobinage et l'inductance ajoutée par les connexions. Cette dernière peut devenir prépondérante. Afin d'expliquer l'évolution de l'impédance du bobinage en fonction de la fréquence, nous décrivons un modèle analytique qui donne la densité du courant dans le bobinage et l'impédance de ce dernier. En outre, ce modèle permet de déterminer la fréquence de résonance série de divers types de condensateurs ce qui permet de déduire l'influence de la hauteur des condensateurs et de leurs rayons interne et externe sur les performances. Il apparaît ainsi que, pour diminuer l'inductance équivalente série, il vaut mieux employer des bobinages plats et des bobinages annulaires.

DISCOVERY OF A HIGHLY UNEQUAL-MASS BINARY T DWARF WITH KECK LASER GUIDE STAR ADAPTIVE OPTICS: A COEVALITY TEST OF SUBSTELLAR THEORETICAL MODELS AND EFFECTIVE TEMPERATURES

DOE Office of Scientific and Technical Information (OSTI.GOV)

Liu, Michael C.; Dupuy, Trent J.; Leggett, S. K., E-mail: mliu@ifa.hawaii.ed

Highly unequal-mass ratio binaries are rare among field brown dwarfs, with the mass ratio distribution of the known census described by q {sup (4.9{+-}0.7)}. However, such systems enable a unique test of the joint accuracy of evolutionary and atmospheric models, under the constraint of coevality for the individual components (the 'isochrone test'). We carry out this test using two of the most extreme field substellar binaries currently known, the T1 + T6 {epsilon} Ind Bab binary and a newly discovered 0.''14 T2.0 + T7.5 binary, 2MASS J12095613-1004008AB, identified with Keck laser guide star adaptive optics. The latter is the mostmore » extreme tight binary resolved to date (q {approx} 0.5). Based on the locations of the binary components on the Hertzsprung-Russell (H-R) diagram, current models successfully indicate that these two systems are coeval, with internal age differences of log(age) = -0.8 {+-} 1.3(-1.0{sup +1.2}{sub -1.3}) dex and 0.5{sup +0.4}{sub -0.3}(0.3{sup +0.3}{sub -0.4}) dex for 2MASS J1209-1004AB and {epsilon} Ind Bab, respectively, as inferred from the Lyon (Tucson) models. However, the total mass of {epsilon} Ind Bab derived from the H-R diagram ({approx} 80 M{sub Jup} using the Lyon models) is strongly discrepant with the reported dynamical mass. This problem, which is independent of the assumed age of the {epsilon} Ind Bab system, can be explained by a {approx} 50-100 K systematic error in the model atmosphere fitting, indicating slightly warmer temperatures for both components; bringing the mass determinations from the H-R diagram and the visual orbit into consistency leads to an inferred age of {approx} 6 Gyr for {epsilon} Ind Bab, older than previously assumed. Overall, the two T dwarf binaries studied here, along with recent results from T dwarfs in age and mass benchmark systems, yield evidence for small ({approx}100 K) errors in the evolutionary models and/or model atmospheres, but not significantly larger. Future parallax, resolved

Selected papers from the 7th International Conference on Microtechnologies in Medicine and Biology (MMB 2013)

NASA Astrophysics Data System (ADS)

Meng, Ellis; Takayama, Shuichi

2014-03-01

In this special section of Journal of Micromechanics and Microengineering are a collection of the best microengineering papers presented at the 7th International Conference on Microtechnologies in Medicine and Biology (MMB 2013) which took place in the seaside town of Marina del Rey, California, USA on 10-12 April, 2013. During the 3-day conference, participants enjoyed talks from 6 invited keynote speakers and 125 flash oral/poster presentations. The MMB conference is a biennial meeting with the primary purpose of fostering interactions between biologists and medical researchers, clinicians, chemists, physicists and engineers to enhance and strengthen the potential microtechnologies that will revolutionize the fields of medicine and biological sciences. The conference possesses a unique format where all poster presenters provide a brief 60 s oral presentation highlighting their research. This format was devised to provide training and exposure for young researchers, especially PhD students and postdocs, in the field and stimulate interdisciplinary exchanges. Therefore, MMB provides an intimate intellectual venue the facilitate discussions and collaborations to advance new research tools and technologies for medicine and biological sciences. The MMB conference series was co-founded by Professor David Beebe (University of Wisconsin—Madison) and Professor André Dittmar (University of Lyon) and was the first international meeting to provide a forum focusing on emerging applications of microtechnologies to unmet needs in medicine and biology. The series was held for the first time in 2000, in Lyon, France and followed by Madison, USA (2002), Oahu Island in Hawaii, USA (2005), Okinawa, Japan (2006), Québec City, Canada (2009), Lucerne, Switzerland (2011), and Marina del Rey, USA (2013). The next conference will be held in Seoul, Korea in 2015. This collection of articles highlights recent progress in microtechnologies with medical and biological applications. We are

Apport des neutrons à l'analyse structurale des composés partiellement désordonnés

NASA Astrophysics Data System (ADS)

Cousson, A.

2003-02-01

La cristallographie est un outil extrêmement puissant qui pourrait être utilisé par de nombreux scientifiques dont les sujets de recherche sont en fait très éloignés. L'évolution des techniques ces dernières années a relégué par exemple la cristallographie des rayons X des petites molécules à un rôle mineur, un rôle de service. Certains ont même le sentiment semble-t-il que toutes les connaissances sont contenues dans de multiples logiciels capables par eux-mêmes de conduire une analyse structurale à un résultat correct unique. Il est souhaitable que chacun soit capable de réaliser l'étude structurale du composé qui l'intéresse et bien entendu nécessaire de comprendre ce que l'on fait, la qualité des résultats et leur analyse en dépend. L'objet de cette présentation est de montrer l'apport spécifique de la diffraction de neutrons sur monocristaux à l'étude du désordre, en particulier des atomes d'hydrogène, et ses conséquences sur la compréhension des propriétés physiques, à partir de développements et d'exemples récents.

Apport des moyens endoscopiques dans la dilatation des sténoses caustiques de l’œsophage

PubMed Central

Seydou, Togo; Abdoulaye, Ouattara Moussa; xing, Li; Zi, Sanogo Zimogo; sekou, Koumaré; Wen, Yang Shang; Ibrahim, Sankare; Sekou, Toure Cheik Ahmed; Boubacar, Maiga Ibrahim; Saye, Jacque; Jerome, Dakouo Dodino; Dantoumé, Toure Ousmane; Sadio, Yena

2016-01-01

Introduction Toutes les sténoses symptomatiques de l’œsophage peuvent être dilatées par voie endoscopique. Nous évaluons l'apport des moyens endoscopiques dans la prise en charge de la dilatation œsophagienne pour sténose caustique de l’œsophage (SCO) au Mali. Méthodes IL s'agissait d'une étude descriptive et prospective réalisée dans le service de chirurgie thoracique à l'hôpital du Mali. Au total 46 dossiers cliniques de patients on été enregistrés et subdivisés en 4 groupes en fonction de la topographie des lésions cicatricielles. Le nombre de cas d'assistance endoscopique réalisé a été déterminé afin de comprendre l'apport des moyens endoscopiques dans le succès de la dilatation des SCO. Pour les 2 différentes méthodes de dilatation utilisées, le résultat du traitement et le coût ont comparés. Résultats La FOGD a été utilisée dans 19 cas (41.30%) de dilatation avec la bougie de Savary Guillard et dans 47.82% des cas dans la dilatation de Lerut. La vidéo-laryngoscopie a été utilisé 58.69% des cas de dilatation à la bougie de Lerut. Le passage de guide métallique et / ou de fil-guide a été réalisée dans 39.13% avec la vidéo laryngoscopie et dans 58.68% avec la FOGD. Dans la comparaison des deux méthodes, il existe une différence significative dans la survenue des complications (p=0.04075), l'anesthésie générale (p=0.02287), l'accessibilité à la méthode (p=0.04805) et la mortalité (p=0.00402). Conclusion La SCO est une pathologie grave et sous évaluée au Mali. Les moyens endoscopiques contribuent considérablement au succès de la dilatation œsophagienne pour sténose caustique dans les différentes méthodes utilisées. PMID:27200129

Fissuration en relaxation des aciers inoxydables austénitiques au voisinage des soudures

NASA Astrophysics Data System (ADS)

Auzoux, Q.; Allais, L.; Gourgues, A. F.; Pineau, A.

2003-03-01

Des fissures intergranulaires peuvent se développer au voisinage des soudures des aciers inoxydables austénitiques lorsqu'ils sont réchauffés dans le domaine de température compris entre 500^{circ}C et 700^{circ}C. A ces températures, les contraintes résiduelles post-soudage se relaxent par déformation viscoplastique. Il peut arriver que ces zones proches de la soudure soient tellement fragiles, qu'elles ne puissent accommoder cette faible déformation. Afin de préciser quelles peuvent être les modifications microstructurales qui conduisent à une telle fragilisation, on a examiné les microstructures de ces zones et révélé ainsi un écrouissage résiduel, responsable d'une forte élévation de la dureté. On a pu reproduire par hypertrempe puis laminage entre 400^{circ}C et 600^{circ}C une microstructure similaire. Des essais mécaniques (traction, fluage, relaxation, sur éprouvettes lisses et pré-fissurées) ont été réalisés à 550^{circ}C et à 600^{circ}C sur ces zones affectées simulées et sur un état de référence hypertrempé. Ils ont montré que l'écrouissage diminuait la ductilité dans le domaine de rupture intergranulaire, sans modifier qualitativement le mécanisme d'endommagement. Pendant la pré-déformation les incompatibilités de déformation entre grains conduiraient à l'existence de contraintes locales élevées qui favoriseraient la germination des cavités intergranulaires.

Comparaison des effets des irradiations γ, X et UV dans les fibres optiques

NASA Astrophysics Data System (ADS)

Girard, S.; Ouerdane, Y.; Baggio, J.; Boukenter, A.; Meunier, J.-P.; Leray, J.-L.

2005-06-01

Les fibres optiques présentent de nombreux avantages incitant à les intégrer dans des applications devant résister aux environnements radiatifs associés aux domaines civil, spatial ou militaire. Cependant, leur exposition à un rayonnement entraîne la création de défauts ponctuels dans la silice amorphe pure ou dopée qui constitue les différentes parties de la fibre optique. Ces défauts causent, en particulier, une augmentation transitoire de l'atténuation linéique des fibres optiques responsable de la dégradation voire de la perte du signal propagé dans celles-ci. Dans cet article, nous comparons les effets de deux types d'irradiation: une impulsion X et une dose γ cumulée. Les effets de ces irradiations sont ensuite comparés avec ceux induits par une insolation ultraviolette (244 nm) sur les propriétés d'absorption des fibres optiques. Nous montrons qu'il existe des similitudes entre ces différentes excitations et qu'il est possible, sous certaines conditions, d'utiliser celles-ci afin d'évaluer la capacité de certaines fibres optiques à fonctionner dans un environnement nucléaire donné.

Vers des boites quantiques a base de graphene

NASA Astrophysics Data System (ADS)

Branchaud, Simon

Le graphene est un materiau a base de carbone qui est etudie largement depuis 2004. De tres nombreux articles ont ete publies tant sur les proprietes electroniques, qu'optiques ou mecaniques de ce materiel. Cet ouvrage porte sur l'etude des fluctuations de conductance dans le graphene, et sur la fabrication et la caracterisation de nanostructures gravees dans des feuilles de ce cristal 2D. Des mesures de magnetoresistance a basse temperature ont ete faites pres du point de neutralite de charge (PNC) ainsi qu'a haute densite electronique. On trouve deux origines aux fluctuations de conductance pres du PNC, soit des oscillations mesoscopiques provenant de l'interference quantique, et des fluctuations dites Hall quantique apparaissant a plus haut champ (>0.5T), semblant suivre les facteurs de remplissage associes aux monocouches de graphene. Ces dernieres fluctuations sont attribuees a la charge d'etats localises, et revelent un precurseur a l'effet Hall quantique, qui lui, ne se manifeste pas avant 2T. On arrive a extraire les parametres caracterisant l'echantillon a partir de ces donnees. A la fin de cet ouvrage, on effectue des mesures de transport dans des constrictions et ilots de graphene, ou des boites quantiques sont formees. A partir de ces mesures, on extrait les parametres importants de ces boites quantiques, comme leur taille et leur energie de charge.

Prise en charge des troubles de consommation d’opioïdes en première ligne

PubMed Central

Srivastava, Anita; Kahan, Meldon; Nader, Maya

2017-01-01

Résumé Objectif Conseiller les médecins quant aux options thérapeutiques à recommander à des populations précises de patients : approche axée sur l’abstinence, traitement d’entretien par la buprénorphine-naloxone ou traitement d’entretien par la méthadone. Sources d’information Une recherche sur PubMed a été effectuée, et on a relevé dans les publications les données sur l’efficacité, l’innocuité et le profil d’effets indésirables de l’approche axée sur l’abstinence, du traitement par la buprénorphine-naloxone et du traitement par la méthadone. Les études d’observation et interventionnelles ont été incluses. Message principal La méthadone et la buprénorphine-naloxone sont substantiellement plus efficaces que l’approche axée sur l’abstinence. La méthadone présente un taux de rétention plus élevé que la buprénorphine-naloxone, alors que la buprénorphine-naloxone présente un risque plus faible de surdose. Les médecins devraient recommander le traitement par la méthadone ou la buprénorphine-naloxone plutôt que l’approche axée sur l’abstinence, et ce, à tous les groupes de patients (données de niveau I). La méthadone est préférable à la buprénorphine-naloxone chez les patients qui présentent un risque élevé d’abandon, comme les usagers d’opioïdes par injection (données de niveau I). Les jeunes et les femmes enceintes qui font usage d’opioïdes par injection devraient aussi recevoir la méthadone d’abord (données de niveau III). Si la buprénorphine-naloxone est prescrite en premier, il faut faire passer rapidement le patient à la méthadone si les symptômes de sevrage, les fortes envies ou la consommation d’opioïdes persistent malgré une dose optimale de buprénorphine-naloxone (données de niveau II). La buprénorphine-naloxone est recommandée chez les usagers d’opioïdes sur ordonnance par voie orale socialement stables, surtout s’ils ont un emploi ou si leurs

Determination dans les Installations au Sol des Parametres Aerodynamiques de Stabilite des Aeronefs (Determination in Ground Facilities of Aerodynamic Stability Parameters of Aircraft),

DTIC Science & Technology

1979-06-01

7 INTRODUCTION ...................................................................................... 12 CHAPITRE I : ELEMENTS DE DYNAMIQUE...daone Ie texts. 12 INTRODUCTION La ddtermination des ddrivdes adrodynamiques de stabilitd, en soufflerie et au tunnel de tir, aur des maquettes...ddtection des forces eat effectuds de fegon classiqus depuis plus de vingt ana par des barreaux d’acier dquipds de jauges de contrainte, gdndralament en

Lignes directrices canadiennes sur l’utilisation sécuritaire et efficace des opioïdes pour la douleur chronique non cancéreuse

PubMed Central

Kahan, Meldon; Mailis-Gagnon, Angela; Wilson, Lynn; Srivastava, Anita

2011-01-01

Résumé Objectif Présenter aux médecins de famille un résumé clinique pratique des lignes directrices canadiennes sur l’utilisation sécuritaire et efficace des opioïdes pour la douleur chronique non cancéreuse, produites par le National Opioid Use Guideline Group. Qualité des données Pour produire les lignes directrices, les chercheurs ont effectué une synthèse critique de la littérature médicale sur l’efficacité et l’innocuité des opioïdes pour la douleur chronique non cancéreuse et ont rédigé une série de recommandations. Un panel de 49 cliniciens experts de toutes les régions du Canada ont passé en revue l’ébauche et ont atteint un consensus sur 24 recommandations. Message principal Il est recommandé de faire un dépistage du risque de dépendance avant de prescrire des opioïdes. On recommande des opioïdes faibles (codéine et tramadol) pour une douleur de légère à modérée qui n’a pas répondu aux traitements de première intention. On peut essayer l’oxycodone, l’hydromorphone et la morphine chez les patients qui n’ont pas eu de soulagement avec des opioïdes plus faibles. Une faible dose initiale et une lente hausse du titrage sont recommandées, ainsi qu’une étroite surveillance du patient qu’on a d’abord renseigné. Les médecins doivent surveiller l’apparition de complications comme l’apnée du sommeil. La dose optimale est celle qui améliore le fonctionnement ou atténue les cotes d’évaluation de la douleur d’au moins 30 %. Pour la grande majorité des patients, la dose optimale sera bien en deçà de l’équivalent de 200 mg de morphine par jour. On recommande le sevrage progressif pour les patients qui n’ont pas répondu à un essai d’opioïdes adéquat. Conclusion Les opioïdes jouent un rôle important dans la prise en charge de la douleur chronique non cancéreuse, mais il faut en prescrire avec prudence pour limiter les dommages potentiels. Les nouvelles lignes directrices

Des recommandations probantes pour surveiller l’innocuité des antipsychotiques de deuxième génération chez les enfants et les adolescents

PubMed Central

Pringsheim, Tamara; Panagiotopoulos, Constadina; Davidson, Jana; Ho, Josephine

2012-01-01

HISTORIQUE : Au Canada, l’utilisation d’antipsychotiques, notamment les antipsychotiques de deuxième génération (ADG), a augmenté de façon considérable depuis cinq ans chez les enfants ayant des troubles de santé mentale. Ces médicaments ont le potentiel de causer de graves complications métaboliques et neurologiques lorsqu’on les utilise de manière chronique. OBJECTIF : Synthétiser les données probantes relatives aux effets secondaires métaboliques et neurologiques précis associés à l’usage d’ADG chez les enfants et fournir des recommandations probantes sur la surveillance de ces effets secondaires. MÉTHODOLOGIE : Les auteurs ont procédé à une analyse systématique des essais cliniques contrôlés des ADG auprès d’enfants. Ils ont fait des recommandations à l’égard de la surveillance de l’innocuité des ADG d’après un modèle de classification fondé sur le système GRADE (système de notation de l’évaluation et de l’élaboration des recommandations). Lorsque les données probantes n’étaient pas suffisantes, ils fondaient leurs recommandations sur le consensus et l’avis d’experts. Un groupe consensuel multidisciplinaire a analysé toutes les données probantes pertinentes et est parvenu à un consensus à l’égard des recommandations. RÉSULTATS : Les recommandations probantes portant sur la surveillance de l’innocuité des ADG figurent dans les présentes lignes directrices. Les auteurs indiquent la qualité des recommandations relatives à des examens physiques et tests de laboratoire précis à l’égard de chaque ADG à des moments déterminés. CONCLUSION : De multiples essais aléatoires et contrôlés ont permis d’évaluer l’efficacité de bon nombre des ADG utilisés pour traiter les troubles de santé mentale en pédiatrie. Toutefois, leurs avantages ne sont pas sans risques : on observe à la fois des effets secondaires métaboliques et neurologiques chez les enfants traités au moyen d�

Influence du comportement des accompagnants sur le vécu des patients admis pour hémorragies digestives hautes au CHU campus de Lomé (Togo)

PubMed Central

Bagny, Aklesso; Dusabe, Angelique; Bouglouga, Oumboma; Lawson-ananisoh, Mawuli Late; Kaaga, Yeba Laconi; Djibril, Mohaman Awalou; Soedje, Kokou Mensah; Dassa, Simliwa Kolou; Redah, Datouda

2014-01-01

Introduction L'hémorragie digestive haute est une urgence, qui constitue souvent pour les patients un danger mortel suscitant inquiétude et agitation. Dans cet état, le patient dépend de ses accompagnants pour ses soins et pour honorer le traitement; mais souvent, il a été observé une discordance entre l'urgence et les comportements des accompagnants. Le but de cette étude était de décrire les facteurs socioéconomiques et psychologiques pouvant influencer les comportements des accompagnants des patients admis pour HDH, estimer l'indice de relation entre ces comportements et les facteurs associés d'une part et le vécu des patients admis pour HDH d'autre part. Méthodes Il s'agit d'une étude prospective menée de Septembre 2010 à Juin 2011 (soit 10 mois). Nous avions utilisé l'entretien semi-dirigé et l'observation directe pour collecter nos données, ces dernières avaient été traitées par les méthodes statistiques et d'analyse de contenu. Résultats Dans la présente étude, les comportements des accompagnants des patients admis pour HDH sont en majorité marqués par l'abandon (84%) et le manque de sollicitude (80,2%). Ces comportements sont souvent stimulés par les facteurs socioéconomiques tels que les difficultés économiques (83,2%), des conflits intrafamiliaux (85,1%) et des représentations (maladie incurable ou envoûtement) de la maladie par les accompagnants (73,3%) des cas. Quant aux patients, ils vivent ces comportements comme étant des menaces de mort ou des rejets (77,20%) et comme étant une dévalorisation ou une humiliation de la part de leurs accompagnants (70,30%). Les résultats confirment l'existence de lien significatif entre les comportements des accompagnants et les facteurs socio économiques, entre les comportements des accompagnants et des facteurs psychologiques, et entre le vécu des patients admis pour l'HDH et les comportements des accompagnants. Conclusion Des études ultérieures devraient aborder les points

Scramjet Thermal Management (Tenue thermique des superstatoreacteurs)

DTIC Science & Technology

2010-09-01

RTO-EN-AVT-185 13 - 1 Scramjet Thermal Management (Tenue thermique des superstatoréacteurs) Marc BOUCHEZ MBDA France Rond-point Marcel...SPEED PROPULSION: ENGINE DESIGN – INTEGRATION AND THERMAL MANAGEMENT” fut donné à l’Institut Von Karman en septembre 2010 et à l’Université Wright de ...Dayton (Ohio, USA) en décembre 2010. Le présent cours aborde la tenue thermique. Il est basé sur des informations publiées, et des détails

Classification of 13 DES supernova with OzDES

NASA Astrophysics Data System (ADS)

Macaulay, E.; Allam, S.; Tucker, D.; Asorey, J.; Davis, T. M.; Kremlin, A.; Lewis, G. F.; Lidman, C.; Martini, P.; Sommer, N. E.; Tucker, B. E.; Aldering, G.; Gupta, R.; Kim, A. G.; Thomas, R. C.; Barbary, K.; Bloom, J. S.; Goldstein, D.; Nugent, P.; Perlmutter, S.; Foley, R. J.; Pan, Y.-C.; Casas, R.; Castander, F. J.; Papadopoulos, A.; Morganson, E.; Desai, S.; Paech, K.; Smith, R. C.; Schubnell, M.; Moller, A.; Muthukrishna, D. R.; Yuan, F.; Zhang, B.; Hinton, S.; Parkinson, D.; Uddin, S.; Kessler, R.; Lasker, J.; Scolnic, D.; Brout, D. J.; D'Andrea, C.; Gladney, L.; March, M.; Sako, M.; Wolf, R. C.; Brown, P. J.; Krisciunas, K.; Suntzeff, N.; Nichol, R.; Maartens, R.; Childress, M.; Prajs, S.; Smith, M.; Sullivan, M.; Kovacs, E.; Kuhlmann, S.; Spinka, H.; Ahn, E.; Finley, D. A.; Frieman, J.; Marriner, J.; Wester, W.

2018-01-01

We report new spectroscopic classifications by OzDES of supernovae discovered by the Dark Energy Survey (ATEL #4668). The spectra (370-885nm) were obtained with the AAOmega Spectrograph (Saunders et al. 2004, SPIE, 5492, 389) and the 2dF fibre positioner at the Anglo-Australian Telescope (AAT).

Classification of 26 DES supernova with OzDES

NASA Astrophysics Data System (ADS)

Calcino, J.; Davis, T. M.; Hoormann, J. K.; Asorey, J.; Glazebrook, K.; Carnero, A.; Lidman, C.; Martini, P.; Moller, A.; Sommer, N. E.; Sharp, R.; Tucker, B. E.; Barbary, K.; Bloom, J. S.; Goldstein, D.; Nugent, P.; Perlmutter, S.; Foley, R. J.; Pan, Y.-C.; Casas, R.; Castander, F. J.; Papadopoulos, A.; Morganson, E.; Desai, S.; Paech, K.; Smith, R. C.; Schubnell, M.; Muthukrishna, D. R.; Yuan, F.; Zhang, B.; Hinton, S.; Lewis, G. F.; Parkinson, D.; Uddin, S.; Kessler, R.; Lasker, J.; Scolnic, D.; Brout, D. J.; D'Andrea, C.; Gladney, L.; March, M.; Sako, M.; Wolf, R. C.; Brown, P. J.; Krisciunas, K.; Suntzeff, N.; Macaulay, E.; Nichol, R.; Maartens, R.; Childress, M.; Prajs, S.; Smith, M.; Sullivan, M.; Kovacs, E.; Kuhlmann, S.; Spinka, H.; Ahn, E.; Finley, D. A.; Frieman, J.; Marriner, J.; Wester, W.; Aldering, G.; Gupta, R.; Kim, A. G.; Thomas, R. C.

2018-01-01

We report new spectroscopic classifications by OzDES of supernovae discovered by the Dark Energy Survey (ATEL #4668). The spectra (370-885nm) were obtained with the AAOmega Spectrograph (Saunders et al. 2004, SPIE, 5492, 389) and the 2dF fibre positioner at the Anglo-Australian Telescope (AAT).

Classification of 25 DES supernova with OzDES

NASA Astrophysics Data System (ADS)

Calcino, J.; Davis, T. M.; Hoormann, J. K.; Asorey, J.; Glazebrook, K.; Carnero, A.; Lidman, C.; Martini, P.; Moller, A.; Sommer, N. E.; Sharp, R.; Tucker, B. E.; Barbary, K.; Bloom, J. S.; Goldstein, D.; Nugent, P.; Perlmutter, S.; Foley, R. J.; Pan, Y.-C.; Casas, R.; Castander, F. J.; Papadopoulos, A.; Morganson, E.; Desai, S.; Paech, K.; Smith, R. C.; Schubnell, M.; Muthukrishna, D. R.; Yuan, F.; Zhang, B.; Hinton, S.; Lewis, G. F.; Parkinson, D.; Uddin, S.; Kessler, R.; Lasker, J.; Scolnic, D.; Brout, D. J.; D'Andrea, C.; Gladney, L.; March, M.; Sako, M.; Wolf, R. C.; Brown, P. J.; Krisciunas, K.; Suntzeff, N.; Macaulay, E.; Nichol, R.; Maartens, R.; Childress, M.; Prajs, S.; Smith, M.; Sullivan, M.; Kovacs, E.; Kuhlmann, S.; Spinka, H.; Ahn, E.; Finley, D. A.; Frieman, J.; Marriner, J.; Wester, W.; Aldering, G.; Gupta, R.; Kim, A. G.; Thomas, R. C.

2018-01-01

We report new spectroscopic classifications by OzDES of supernovae discovered by the Dark Energy Survey (ATEL #4668). The spectra (370-885nm) were obtained with the AAOmega Spectrograph (Saunders et al. 2004, SPIE, 5492, 389) and the 2dF fibre positioner at the Anglo-Australian Telescope (AAT).

Classification of 18 DES supernova with OzDES

NASA Astrophysics Data System (ADS)

Swann, E. S.; Lewis, G. F.; Lidman, C.; Panther, F. H.; Sharp, R.; Sommer, N. E.; Tucker, B. E.; Muthukrishna, D.; Casas, R.; Castander, F. J.; Papadopoulos, A.; Morganson, E.; Desai, S.; Paech, K.; Smith, R. C.; Schubnell, M.; Moller, A. R.; Yuan, F.; Zhang, B.; Davis, T. M.; Hinton, S.; Asorey, J.; Uddin, S.; Kessler, R.; Lasker, J.; Scolnic, D.; Brout, D. J.; D'Andrea, C.; Gladney, L.; March, M.; Sako, M.; Wolf, R. C.; Brown, P. J.; Krisciunas, K.; Suntzeff, N.; Macaulay, E.; Nichol, R.; Maartens, R.; Childress, M.; Prajs, S.; Smith, M.; Sullivan, M.; Kovacs, E.; Kuhlmann, S.; Spinka, H.; Ahn, E.; Finley, D. A.; Frieman, J.; Marriner, J.; Wester, W.; Aldering, G.; Gupta, R.; Kim, A. G.; Thomas, R. C.; Barbary, K.; Bloom, J. S.; Goldstein, D.; Nugent, P.; Perlmutter, S.; Foley, R. J.; Pan, Y.-C.

2018-06-01

We report new spectroscopic classifications by OzDES of supernovae discovered by the Dark Energy Survey (ATEL #4668). The spectra (370-885nm) were obtained with the AAOmega Spectrograph (Saunders et al. 2004, SPIE, 5492, 389) and the 2dF fibre positioner at the Anglo-Australian Telescope (AAT).

Classification of 17 DES supernova with OzDES

NASA Astrophysics Data System (ADS)

Muthukrishna, D.; Sharp, R. G.; Tucker, B. E.; Moller, A.; Sommer, N. E.; Asorey, J.; Lewis, G. F.; Lidman, C.; Mould, J.; Macaulay, E.; Maartens, R.; Kovacs, E.; Kuhlmann, S.; Spinka, H.; Ahn, E.; Finley, D. A.; Frieman, J.; Marriner, J.; Wester, W.; Aldering, G.; Gupta, R.; Kim, A. G.; Thomas, R. C.; Barbary, K.; Bloom, J. S.; Goldstein, D.; Nugent, P.; Perlmutter, S.; Foley, R. J.; Pan, Y.-C.; Casas, R.; Castander, F. J.; Papadopoulos, A.; Morganson, E.; Desai, S.; Paech, K.; Smith, R. C.; Schubnell, M.; Yuan, F.; Zhang, B.; Davis, T. M.; Hinton, S.; Parkinson, D.; Uddin, S.; Kessler, R.; Lasker, J.; Scolnic, D.; Brout, D. J.; D'Andrea, C.; Gladney, L.; March, M.; Sako, M.; Wolf, R. C.; Brown, P. J.; Krisciunas, K.; Suntzeff, N.; Nichol, R.; Childress, M.; Prajs, S.; Smith, M.; Sullivan, M.

2017-09-01

We report new spectroscopic classifications by OzDES of supernovae discovered by the Dark Energy Survey (ATEL #4668). The spectra (370-885nm) were obtained with the AAOmega Spectrograph (Saunders et al. 2004, SPIE, 5492, 389) and the 2dF fibre positioner at the Anglo-Australian Telescope (AAT).

Influence des défauts de la structure du verre sur la résistance mécanique des fibres optiques

NASA Astrophysics Data System (ADS)

Chmel, A.; Baptizmanski, V. V.; Kharshak, A. A.

1992-12-01

For silica (pure and doped) optical fibers prepared from preforms irradiated by thermal neutrons and Ar^+ ions, the measurements of lifetime under transverse stress were carried out. It is found that the neutron bombardment leads to decrease of the lifetime and the strength of fiber while the ion implantation results in increasing of these parameters. The influence of particle irradiation on the glass strength is explained by the generation of structural defects which were observed by the infrared an Raman spectroscopy methods. The direction of the change of mechanical properties of fibers is determined by the type of defects and their distribution in the cross-section of fiber. Des préformes de fibres optiques de silice ont été exposées à un bombardement par des faisceaux de neutrons thermiques et d'ions Ar^+ à énergie de 40 keV afin d'engendrer des défauts de la structure respectivement dans le volume ou dans la couche superficielle des échantillons. Les fibres obtenues des préformes irradiées et non irradiées ont été mises en charge de flexion. On a déterminé leur temps de rupture sous diverses contraintes de traction sur la surface extérieure de la fibre en flexion. On a observé une diminution du temps de rupture des fibres après le bombardement neutronique et une augmentation après l'implantation ionique. L'analyse de la nature des défauts en faisant appel à la spectroscopie infrarouge et Raman a fait ressortir que l'irradiation aux ions entraînait essentiellement des liaisons chimiques dans une fine couche superficielle de l'échantillon alors que l'irradiation aux neutrons occasionnait une déformation des zones du réseau silicique dans toute la section de la préforme et de la fibre. L'amélioration de la résistance mécanique s'explique par une augmentation de la mobilité des éléments structuraux de la matrice de verre par suite d'une rupture partielle des liaisons chimiques et sa diminution par l'apparition de concentrateurs

Etude de la dynamique des porteurs dans des nanofils de silicium par spectroscopie terahertz

NASA Astrophysics Data System (ADS)

Beaudoin, Alexandre

Ce memoire presente une etude des proprietes de conduction electrique et de la dynamique temporelle des porteurs de charges dans des nanofils de silicium sondes par rayonnement terahertz. Les cas de nanofils de silicium non intentionnellement dopes et dopes type n sont compares pour differentes configurations du montage experimental. Les mesures de spectroscopie terahertz en transmission montre qu'il est possible de detecter la presence de dopants dans les nanofils via leur absorption du rayonnement terahertz (˜ 1--12 meV). Les difficultes de modelisation de la transmission d'une impulsion electromagnetique dans un systeme de nanofils sont egalement discutees. La detection differentielle, une modification au systeme de spectroscopie terahertz, est testee et ses performances sont comparees au montage de caracterisation standard. Les instructions et des recommendations pour la mise en place de ce type de mesure sont incluses. Les resultats d'une experience de pompe optique-sonde terahertz sont egalement presentes. Dans cette experience, les porteurs de charge temporairement crees suite a l'absorption de la pompe optique (lambda ˜ 800 nm) dans les nanofils (les photoporteurs) s'ajoutent aux porteurs initialement presents et augmentent done l'absorption du rayonnement terahertz. Premierement, l'anisotropie de l'absorption terahertz et de la pompe optique par les nanofils est demontree. Deuxiemement, le temps de recombinaison des photoporteurs est etudie en fonction du nombre de photoporteurs injectes. Une hypothese expliquant les comportements observes pour les nanofils non-dopes et dopes-n est presentee. Troisiemement, la photoconductivite est extraite pour les nanofils non-dopes et dopes-n sur une plage de 0.5 a 2 THz. Un lissage sur la photoconductivite permet d'estimer le nombre de dopants dans les nanofils dopes-n. Mots-cles: nanofil, silicium, terahertz, conductivite, spectroscopie, photoconductivite.

Methodes iteratives paralleles: Applications en neutronique et en mecanique des fluides

NASA Astrophysics Data System (ADS)

Qaddouri, Abdessamad

Dans cette these, le calcul parallele est applique successivement a la neutronique et a la mecanique des fluides. Dans chacune de ces deux applications, des methodes iteratives sont utilisees pour resoudre le systeme d'equations algebriques resultant de la discretisation des equations du probleme physique. Dans le probleme de neutronique, le calcul des matrices des probabilites de collision (PC) ainsi qu'un schema iteratif multigroupe utilisant une methode inverse de puissance sont parallelises. Dans le probleme de mecanique des fluides, un code d'elements finis utilisant un algorithme iteratif du type GMRES preconditionne est parallelise. Cette these est presentee sous forme de six articles suivis d'une conclusion. Les cinq premiers articles traitent des applications en neutronique, articles qui representent l'evolution de notre travail dans ce domaine. Cette evolution passe par un calcul parallele des matrices des PC et un algorithme multigroupe parallele teste sur un probleme unidimensionnel (article 1), puis par deux algorithmes paralleles l'un mutiregion l'autre multigroupe, testes sur des problemes bidimensionnels (articles 2--3). Ces deux premieres etapes sont suivies par l'application de deux techniques d'acceleration, le rebalancement neutronique et la minimisation du residu aux deux algorithmes paralleles (article 4). Finalement, on a mis en oeuvre l'algorithme multigroupe et le calcul parallele des matrices des PC sur un code de production DRAGON ou les tests sont plus realistes et peuvent etre tridimensionnels (article 5). Le sixieme article (article 6), consacre a l'application a la mecanique des fluides, traite la parallelisation d'un code d'elements finis FES ou le partitionneur de graphe METIS et la librairie PSPARSLIB sont utilises.

Review on physical and chemical characterizations of contaminated sediments from urban stormwater infiltration basins within the framework of the French observatory for urban hydrology (SOERE URBIS).

PubMed

El-Mufleh, Amelène; Béchet, Béatrice; Ruban, Véronique; Legret, Michel; Clozel, Blandine; Barraud, Sylvie; Gonzalez-Merchan, Carolina; Bedell, Jean-Philippe; Delolme, Cécile

2014-04-01

Urban stormwater infiltration basins are designed to hold runoff from impervious surfaces and allow the settling of sediments and associated pollutants. However concerns have been expressed about the environmental impacts that may be exerted by the trapped pollutants on groundwater, soils and ecosystems. In this context, sediment characterization represents a key issue for local authorities in terms of management strategies. During the last two decades, several studies were launched including either physical or chemical characterization of stormwater sediments but without real synthesis of data and methods used. Consequently, there is an important need for reviewing the current experimental techniques devoted to the physico-chemical characterization of sediment. The review is based on the outcomes of two experimental sites for which long term monitoring and data collection have been done: the Cheviré basin (near Nantes) and the Django Reinhardt basin (near Lyon). The authors summarize the studies dealing with bulk properties, pollutant contents, their potential mobility and speciation. This paper aims at promoting the significant progresses that were made through a multidisciplinary approach involving multi-scaled and combined experimental techniques.

KSC Center Director Bridges accepts an ISO 9001 certification plaque from DNV

NASA Technical Reports Server (NTRS)

1998-01-01

Center Director Roy Bridges (right) displays the 2000th ISO Certificate Plaque he was given by Dalton Lyon (left) of Det Norske Veritas (DNV), Inc., an international ISO certification organization, at a ceremony at KSC. The plaque is a representation of the ISO 9001 certification awarded to KSC by DNV. ISO 9001 comprises the most detailed, comprehensive set of standard requirements for quality programs established by the International Standards Organization. The presentation followed a successful independent audit by DNV of the KSC Management System in May of this year. The third-party auditors examined about 20 elements of KSC's system, including management responsibility, design control, documentation, test and inspection, and corrective action procedures. DNV found that KSC met or exceeded the stringent quality standards in all areas. KSC will use this certification as a tool to improve an already world- class team. All NASA centers are required by NASA Administrator Daniel S. Goldin to be ISO 9001 registered by September 1999. NASA is the first federal agency to seek the quality certification.

Cocaine profiling for strategic intelligence, a cross-border project between France and Switzerland: part II. Validation of the statistical methodology for the profiling of cocaine.

PubMed

Lociciro, S; Esseiva, P; Hayoz, P; Dujourdy, L; Besacier, F; Margot, P

2008-05-20

Harmonisation and optimization of analytical and statistical methodologies were carried out between two forensic laboratories (Lausanne, Switzerland and Lyon, France) in order to provide drug intelligence for cross-border cocaine seizures. Part I dealt with the optimization of the analytical method and its robustness. This second part investigates statistical methodologies that will provide reliable comparison of cocaine seizures analysed on two different gas chromatographs interfaced with a flame ionisation detectors (GC-FIDs) in two distinct laboratories. Sixty-six statistical combinations (ten data pre-treatments followed by six different distance measurements and correlation coefficients) were applied. One pre-treatment (N+S: area of each peak is divided by its standard deviation calculated from the whole data set) followed by the Cosine or Pearson correlation coefficients were found to be the best statistical compromise for optimal discrimination of linked and non-linked samples. The centralisation of the analyses in one single laboratory is not a required condition anymore to compare samples seized in different countries. This allows collaboration, but also, jurisdictional control over data.

KSC-05PD-1055

NASA Technical Reports Server (NTRS)

2005-01-01

KENNEDY SPACE CENTER, FLA. Space Shuttle launch director Michael Leinbach (right) and assistant launch director Doug Lyons support an External Tank (ET) tanking test at Launch Pad 39B from the Launch Control Center. The tanking test is designed to evaluate how the tank, orbiter, solid rocket boosters and ground systems perform under 'cryo-load,' when the tank is filled with the two ultra-low-temperature propellants. The tank filling and draining portion of the test takes about 11 hours. The test also includes a simulated countdown through the hold at T-31 seconds. The test is being conducted to troubleshoot two issues identified by a tanking test held on April 14. Data is being collected to analyze the liquid hydrogen sensors that gave intermittent readings and the liquid hydrogen pressurization relief valve that cycled more times than standard. The tanking tests are part of preparations for Space Shuttle Discovery's Return to Flight mission, STS-114, to the International Space Station. The launch window extends from July 13 through July 31.

Impact of Scedosporium apiospermum complex seroprevalence in patients with cystic fibrosis.

PubMed

Parize, Perrine; Billaud, Sandrine; Bienvenu, Anne L; Bourdy, Stéphanie; le Pogam, Marie A; Reix, Philippe; Picot, Stéphane; Robert, Raymond; Lortholary, Olivier; Bouchara, Jean-Philippe; Durieu, Isabelle

2014-12-01

Species of the Scedosporium apiospermum complex (S. a complex) are emerging fungi responsible for chronic airway colonization in cystic fibrosis (CF) patients. Recent studies performed on Aspergillus fumigatus suggest that the colonization of the airways by filamentous fungi may contribute to the progressive deterioration of lung function. We studied S. a complex seroprevalence, as a marker of close contact between patient and the fungi, in a large monocentric cohort of CF patients attended in a reference centre in Lyon, France. Serum samples from 373 CF patients were analysed. Antibodies against S. a complex were detected in 35 patients (9.4%). In multivariate analysis, S. a complex seropositivity was only associated with seropositivity to A. fumigatus. This study does not suggest an association between sensitization against S. a complex and poorer lung function in CF. Prospective studies are needed to evaluate the impact of both seropositivity and S. a complex colonization on the course of CF. Copyright © 2014 European Cystic Fibrosis Society. Published by Elsevier B.V. All rights reserved.

[Hospital infection in the maternity department. 3 years of surveillance in 9,204 deliveries of which 1,333 were cesarean sections].

PubMed

Tissot-Guerraz, F; Moussy, L; Agniel, F; André, A; Reverdy, M E; Miellet, C C; Audra, P; Putet, G; Sepetjan, M; Dargent, D

1990-01-01

Hospital or nosocomial infection, or infection acquired in hospitals, is a health problem in all hospital departments and particularly in the maternity department. We report on a prospective survey of surveillance of hospital-acquired infections both from the mother and the baby's point of view after delivery vaginally or with caesarean carried out at the obstetrical clinic of the Edouard Herriot Hospital in Lyon (France) over three successive years with a series of 9,204 deliveries. The incidence of infection in women who were delivered without caesarean section was 1.37% when urinary tract infections had been excluded but 13% in women who had caesarean sections. Endometritis, skin infections and urinary tract infections were the leading causes. As far as the newborn were concerned, hospital infection ran at about 2.60% and this in the main was due to staphylococcal pustules in the skin. These figures are still too high and prevention should be based on more information given and more care taken by the whole staff of such a hospital.

Earth Observations taken during Expedition Four

NASA Image and Video Library

2002-05-15

ISS004-E-11807 (15 May 2002) --- This digital photograph, taken through the windows of the International Space Station on May 15, 2002, shows condensation trails over the Rhône Valley in the region west of Lyon, France. Condensation trails-or contrails-are straight lines of ice crystals that form in the wake of jet liners where air temperatures are lower than about -40 degrees Centigrade. Scientists have observed that newer contrails are thin whereas older trails have widened with time as a result of light winds. Because of this tendency for thin contrails to cover greater areas with time, it is estimated that these “artificial clouds” cover 0.1 per cent of the planet’s surface. Percentages are far higher in some places, say the scientists, such as southern California, the Ohio River Valley and parts of Europe, as illustrated here. The climatic impact of such clouds is poorly understood, which is why scientists continue to study them using images such as this.

Mycotoxins as human carcinogens-the IARC Monographs classification.

PubMed

Ostry, Vladimir; Malir, Frantisek; Toman, Jakub; Grosse, Yann

2017-02-01

Humans are constantly exposed to mycotoxins (e.g. aflatoxins, ochratoxins), mainly via food intake of plant and animal origin. The health risks stemming from mycotoxins may result from their toxicity, in particular their carcinogenicity. In order to prevent these risks, the International Agency for Research on Cancer (IARC) in Lyon (France)-through its IARC Monographs programme-has performed the carcinogenic hazard assessment of some mycotoxins in humans, on the basis of epidemiological data, studies of cancer in experimental animals and mechanistic studies. The present article summarizes the carcinogenic hazard assessments of those mycotoxins, especially aflatoxins (aflatoxin B 1 , B 2 , G 1 , G 2 and M 1 ), fumonisins (fumonisin B 1 and B 2 ) and ochratoxin A (OTA). New information regarding the genotoxicity of OTA (formation of OTA-DNA adducts), the role of OTA in oxidative stress and the identification of epigenetic factors involved in OTA carcinogenesis-should they indeed provide strong evidence that OTA carcinogenicity is mediated by a mechanism that also operates in humans-could lead to the reclassification of OTA.

Analysis of positive control STR experiments reveals that results obtained for FGA, D3S1358, and D13S317 condition the success rate of the analysis of routine reference samples.

PubMed

Murigneux, Valentine; Dufour, Anne-Béatrice; Lobry, Jean R; Pène, Laurent

2014-07-01

About 120,000 reference samples are analyzed each year in the Forensic Laboratory of Lyon. A total of 1640 positive control experiments used to validate and optimize the analytical method in the routine process were submitted to a multivariate exploratory data analysis approach with the aim of better understanding the underlying sources of variability. The peak heights of the 16 genetic markers targeted by the AmpFℓSTR(®) Identifiler(®) STR kit were used as variables of interest. Six different 3130xl genetic analyzers located in the same controlled environment were involved. Two major sources of variability were found: (i) the DNA load of the sample modulates all peak heights in a similar way so that the 16 markers are highly correlated, (ii) the genetic analyzer used with a locus-specific response for peak height and a better sensitivity for the most recently acquired. Three markers (FGA, D3S1358, and D13S317) were found to be of special interest to predict the success rate observed in the routine process. © 2014 American Academy of Forensic Sciences.

Submicron particulate organic matter in the urban atmosphere: a new method for real-time measurement, molecular-level characterization and source apportionment

NASA Astrophysics Data System (ADS)

Müller, Markus; Eichler, Philipp; D'Anna, Barbara; Tan, Wen; Wisthaler, Armin

2017-04-01

We used a novel chemical analytical method for measuring submicron particulate organic matter in the atmosphere of three European cities (Innsbruck, Lyon, Valencia). Proton-Transfer-Reaction Time-of-Flight Mass Spectrometry (PTR-ToF-MS) was used in combination with the "chemical analysis of aerosol online" (CHARON) inlet for detecting particulate organic compounds on-line (i.e. without filter pre-collection), in real-time (1-min time resolution), at ng m-3 concentrations, with molecular-level resolution (i.e. obtaining molecular weight and elemental composition information). The CHARON-PTR-ToF-MS system monitored molecular tracers associated with different particle sources including levoglucosan from biomass combustion, PAHs from vehicular traffic, nicotine from cigarette smoking, and monoterpene oxidation products secondarily formed from biogenic emissions. The tracer information was used for interpreting positive matrix factorization (PMF) data which allowed us to apportion the sources of submicron particulate organic matter in the different urban environments. This work was funded through the PIMMS ITN, which was supported by the European Commission's 7th Framework Programme under grant agreement number 287382.

[Nicolas Dobo and Pierre Jame about the army medical general Lucian Jame].

PubMed

Dobo, N; Jame, P

1996-01-01

Lucien Jame was born October the 20th 1891 at Gourdon (Lot). State Police Officer's son, he studied in Lyon at the Military Health School. Called up August the 6th 1914, he shined among many fights and wore a lot of medals. After the armistice he defended his thesis upon "Venereal diseases prophylaxis study". March the 9th 1921, medical Officer in South Algeria, he published some original articles regarding to leprosis, tuberculosis and malaria. After a competitive examination in France, Lucien Jame became a Medical Commanding Officer of Military Health Service in Toulouse where Nicolas Dobo was at his disposal. August the 6th 1943, in the same rank in Algier then in Rabat, Lucien Jame reached the top of his career as Chief Executive of Military Health Service. He planed First French army medical operations through Italy, France and Germany battles. "Grand-Officier de la Légion d'honneur", the Army Medical General Lucien Jame retired but kept on with works dedicated to hygiene and preventive medicine till he died, June the 16th, 1969.

Environmental optimization and shielding for NMR experiments and imaging in the earth's magnetic field.

PubMed

Favre, B; Bonche, J P; Meheir, H; Peyrin, J O

1990-02-01

For many years, a number of laboratories have been working on the applications of very low field NMR. In 1985, our laboratory presented the first NMR images using the earth's magnetic field. However, the use of this technique was limited by the weakness of the signal and the disturbing effects of the environment on the signal-to-noise ratio and on the homogeneity of the static magnetic field. Therefore experiments has to be performed in places with low environmental disturbances, such as open country or large parks. In 1986, we installed a new station in Lyon, in the town's hostile environment. Good NMR signals can now be obtained (with a signal-to-noise ratio better than 200 and a time constant T2 better than 3s for 200-mnl water samples and at a temperature of about 40 degrees C). We report the terrace roof of our faculty building. Gradient coils were used to correct the local inhomogeneities of the earth's magnetic field. We show FIDs and MR images of water-filled tubes made with or without these improvements.

Description of Uncinaria lyonsi n. sp. (Nematoda: Ancylostomatidae) from the California sea lion Zalophus californianus Lesson (Carnivora: Otariidae).

PubMed

Kuzmina, Tetiana A; Kuzmin, Yuriy

2015-02-01

A new species of hookworm, Uncinaria lyonsi n. sp., is described based on morphological studies of the nematodes collected by Dr. E. T. Lyons from the California sea lion Zalophus californianus (Lesson) on San Miguel Island, California, USA. The new species is morphologically similar to three other species of the genus Uncinaria Frölich, 1789 parasitising pinnipeds, U. lucasi Stiles, 1901, U. hamiltoni Baylis, 1933 and U. sanguinis Marcus, Higgins, Šlapeta & Gray, 2014, in the body dimensions, the structure of the buccal capsule, the shape and structure of the male caudal bursa and female genital system. Uncinaria lyonsi n. sp. is differentiated from U. lucasi by having longer spicules and gubernaculum, larger buccal capsule and more slender oesophagus. The new species differs from U. hamiltoni and U. sanguinis in having shorter spicules and narrower buccal capsule. The latter two species also occur in the Southern Hemisphere and are geographically separated from U. lyonsi n. sp. The present study confirms the existence of a host-specific species of Uncinaria in the California sea lion, previously revealed by molecular and biological investigations.

Division G Commission 21: Galactic and Extragalactic Backgrounds Radiation

NASA Astrophysics Data System (ADS)

Murthy, Jayant; Witt, Adolf; Baggaley, W. Jack; Dwek, Eli; Levasseur-Regourd, Anny-Chantal; Mann, Ingrid; Mattila, Kalevi; Watanabe, Jun-Ichi

2016-04-01

Commission 21 was one of the oldest and smallest in the IAU yet one which underwent the most evolution since its inception. It began in 1955 as Light of the Night Sky (Lumière du Ciel Nocturne) under the Presidentship of Jean Dufay (University Observatory at Lyon). As the name suggested, in the years before space observations, its focus was on observations of atmospheric light which, at the time, was the domain of astronomers. Thus the early proceedings of the Commission were dominated by reports of the daytime and nighttime emission as observed from different locations and different conditions. Our knowledge of the Earth's atmosphere is still shaped by these early observations (Meier R.R., 1991, Space Sci. Rev. 58, 1). Members of Commission 21 were key to organizing interational collaborations to set up atmospheric stations at different latitudes, including in the Souther hemisphere and in ensuring a consistent calibration between the instruments. The Commission also bought in results from Soviet scientists in an era where communication was limited by both politics and language.

Rodents and climate: A new model for estimating past temperatures [rapid communication

NASA Astrophysics Data System (ADS)

Legendre, Serge; Montuire, Sophie; Maridet, Olivier; Escarguel, Gilles

2005-06-01

Based on the high correlation between species richness in sigmodontine rodents and temperatures, we propose a new model in order to quantify past climates. Because of the close phylogenetic relationship and the tooth morphological similarity between extant New World cricetids (Sigmodontinae) and fossil European cricetids (Cricetinae s.l.), extant New World sigmodontines are taken as analogues for Old World fossil cricetines. Sigmodontine species richness has been compiled for 282 extant local faunas from North, Central and South America, with corresponding climatic data (temperatures and precipitations). There is almost no correlation between areas covered by local faunas (ranging from 1 km 2 up to 46,000 km 2) and numbers of sigmodontine species in localities ( R2 = 0.027). Number of sigmodontine species in local faunas and mean annual daily temperatures are highly correlated ( R2 = 0.88). The relationships of species richness and precipitation is low ( R2 = 0.19 for mean annual precipitation). The method is exemplified for Old World cricetines using well documented Miocene rodent faunas located in the Lyon area (France MN4-5 to MN10).

A model to forecast data centre infrastructure costs.

NASA Astrophysics Data System (ADS)

Vernet, R.

2015-12-01

The computing needs in the HEP community are increasing steadily, but the current funding situation in many countries is tight. As a consequence experiments, data centres, and funding agencies have to rationalize resource usage and expenditures. CC-IN2P3 (Lyon, France) provides computing resources to many experiments including LHC, and is a major partner for astroparticle projects like LSST, CTA or Euclid. The financial cost to accommodate all these experiments is substantial and has to be planned well in advance for funding and strategic reasons. In that perspective, leveraging infrastructure expenses, electric power cost and hardware performance observed in our site over the last years, we have built a model that integrates these data and provides estimates of the investments that would be required to cater to the experiments for the mid-term future. We present how our model is built and the expenditure forecast it produces, taking into account the experiment roadmaps. We also examine the resource growth predicted by our model over the next years assuming a flat-budget scenario.

Seroprevalence after vaccination of cattle and sheep against Bluetongue Virus (BTV) serotype 8 in Sweden.

PubMed

Hultén, C; Frössling, J; Chenais, E; Sternberg Lewerin, S

2013-10-01

Sweden experienced its first outbreak of bluetongue virus (BTV) infection beginning in September 2008. Mandatory vaccination with an inactivated vaccine (BTVPUR Alsap8; Merial, Lyon, France) began 2 days after bluetongue was confirmed in the country. The aim of this study was to investigate whether the goal of 80% seroconversion by the susceptible population within the vaccination area was met during the initial phase of the Swedish vaccination campaign and whether there were discrepancies between subpopulations. Milk or blood samples were collected from 274 cattle randomly selected from the vaccinated population. Blood samples were also collected from ten ewes on each of 28 randomly selected vaccinated herds. The vaccination campaign in Sweden may be regarded as successful, as measured by apparent seroprevalence in the vaccinated population. The overall apparent seroprevalence was 77%, and in cattle, which constituted the majority of the susceptible population, the apparent seroprevalence was 82%. Factors that influenced the titres after vaccination were as follows: (i) the time span between vaccination and sampling and (ii) the age of the animals. © 2012 Blackwell Verlag GmbH.

KSC-98pc908

NASA Image and Video Library

1998-08-11

Center Director Roy Bridges (right) displays the 2000th ISO Certificate Plaque he was given by Dalton Lyon (left) of Det Norske Veritas (DNV), Inc., an international ISO certification organization, at a ceremony at KSC. The plaque is a representation of the ISO 9001 certification awarded to KSC by DNV. ISO 9001 comprises the most detailed, comprehensive set of standard requirements for quality programs established by the International Standards Organization. The presentation followed a successful independent audit by DNV of the KSC Management System in May of this year. The third-party auditors examined about 20 elements of KSC's system, including management responsibility, design control, documentation, test and inspection, and corrective action procedures. DNV found that KSC met or exceeded the stringent quality standards in all areas. KSC will use this certification as a tool to improve an already worldclass team. All NASA centers are required by NASA Administrator Daniel S. Goldin to be ISO 9001 registered by September 1999. NASA is the first federal agency to seek the quality certification

High incidence of non-tuberculous mycobacteria-positive cultures among adolescent with cystic fibrosis.

PubMed

Cavalli, Zoé; Reynaud, Quitterie; Bricca, Romain; Nove-Josserand, Raphaële; Durupt, Stéphane; Reix, Philippe; Perceval, Marie; de Montclos, Michèle Pérouse; Lina, Gérard; Durieu, Isabelle

2017-09-01

We evaluated the prevalence of non-tuberculous mycobacteria (NTM)-positive cultures among our cystic fibrosis (CF) center patients, reviewed risk factors for NTM positivity, and determined its impact on lung function evolution. From 2009 to 2014, CF adults and children attending the CF center of Lyon (France) and having at least one positive NTM isolate were included. Each case was matched by age and gender with two CF patients with no NTM isolate (controls). 48 CF patients with NTM-positive isolates were matched to 96 controls. The age group for whom incident NTM was higher was young adolescents aged 13 to 17. A significant association for NTM positivity was found with Staphylococcusaureus in multivariate analysis and with allergic bronchopulmonary aspergillosis, corticosteroid and itraconazole in univariate analysis. Mean annual FEV1 decline was faster for NTM-positive patients compared to controls. These data highlight the high incidence of NTM-positive cultures among young adolescents with CF. Copyright © 2017 European Cystic Fibrosis Society. Published by Elsevier B.V. All rights reserved.

X-chromosome dosage as a modulator of pluripotency, signalling and differentiation?

PubMed

Schulz, Edda G

2017-11-05

Already during early embryogenesis, before sex-specific hormone production is initiated, sex differences in embryonic development have been observed in several mammalian species. Typically, female embryos develop more slowly than their male siblings. A similar phenotype has recently been described in differentiating murine embryonic stem cells, where a double dose of the X-chromosome halts differentiation until dosage-compensation has been achieved through X-chromosome inactivation. On the molecular level, several processes associated with early differentiation of embryonic stem cells have been found to be affected by X-chromosome dosage, such as the transcriptional state of the pluripotency network, the activity pattern of several signal transduction pathways and global levels of DNA-methylation. This review provides an overview of the sex differences described in embryonic stem cells from mice and discusses a series of X-linked genes that are associated with pluripotency, signalling and differentiation and their potential involvement in mediating the observed X-dosage-dependent effects.This article is part of the themed issue 'X-chromosome inactivation: a tribute to Mary Lyon'. © 2017 The Author(s).

Dynamical systems theory and applications

NASA Astrophysics Data System (ADS)

Awrejcewicz, Jan

2006-08-01

The 7th International Conference devoted to "Dynamical Systems-Theory and Applications" hold in 8-11 December, 2003 in Łódź, Poland, and it was organized by the staff of Department of Automatics and Biomechanics of the Technical University of Łódź. It was financially supported by the Rector of the Technical University of Łódź and the Department of Education and Physical Culture of the Łódź City Hall. The members of the International Scientific Committee included: Igor V. Andrianov (Dniepropetrovsk), Jan Awrejcewicz (Łódź), Iliya Blekhman (Sankt Petersburg), Roman Bogacz (Warszawa), Dick van Campen (Eindhoven), Zbigniew Engel (Kraków), Lothar Gaul (Stuttgart), Józef Giergiel (Kraków), Michał Kleiber (Warszawa), Vadim A. Krysko (Saratov), Włodzimierz Kurnik (Warszawa), Claude-Henri Lamarque (Lyon), Leonid I. Manevitch (Moscow), Jan Osiecki (Warszawa), Wiesaw Ostachowicz (Gdańsk), Ladislav Pust (Prague), Giuseppe Rega (Rome), Tsuneo Someya (Tokyo), Zbigniew Starczewski (Warszawa), Eugeniusz Świtoński (Gliwice), Andrzej Tylikowski (Warszawa), Tadeusz Uhl (Kraków), Aleksander F. Vakakis (Illinois), Józef Wojnarowski (Gliwice).