A method to integrate descriptive and experimental field studies at the level of data and empirical concepts1

PubMed Central

Bijou, Sidney W.; Peterson, Robert F.; Ault, Marion H.

1968-01-01

It is the thesis of this paper that data from descriptive and experimental field studies can be interrelated at the level of data and empirical concepts if both sets are derived from frequency-of-occurrence measures. The methodology proposed for a descriptive field study is predicated on three assumptions: (1) The primary data of psychology are the observable interactions of a biological organism and environmental events, past and present. (2) Theoretical concepts and laws are derived from empirical concepts and laws, which in turn are derived from the raw data. (3) Descriptive field studies describe interactions between behavioral and environmental events; experimental field studies provide information on their functional relationships. The ingredients of a descriptive field investigation using frequency measures consist of: (1) specifying in objective terms the situation in which the study is conducted, (2) defining and recording behavioral and environmental events in observable terms, and (3) measuring observer reliability. Field descriptive studies following the procedures suggested here would reveal interesting new relationships in the usual ecological settings and would also provide provocative cues for experimental studies. On the other hand, field-experimental studies using frequency measures would probably yield findings that would suggest the need for describing new interactions in specific natural situations. PMID:16795175

Internal Friction And Instabilities Of Rotors

NASA Technical Reports Server (NTRS)

Walton, J.; Artiles, A.; Lund, J.; Dill, J.; Zorzi, E.

1992-01-01

Report describes study of effects of internal friction on dynamics of rotors prompted by concern over instabilities in rotors of turbomachines. Theoretical and experimental studies described. Theoretical involved development of nonlinear mathematical models of internal friction in three joints found in turbomachinery - axial splines, Curvic(TM) splines, and interference fits between smooth cylindrical surfaces. Experimental included traction tests to determine the coefficients of friction of rotor alloys at various temperatures, bending-mode-vibration tests of shafts equipped with various joints and rotordynamic tests of shafts with axial-spline and interference-fit joints.

Postbuckling behavior of graphite-epoxy panels

NASA Technical Reports Server (NTRS)

Starnes, J. H., Jr.; Dickson, J. N.; Rouse, M.

1984-01-01

Structurally efficient fuselage panels are often designed to allow buckling to occur at applied loads below ultimate. Interest in applying graphite-epoxy materials to fuselage primary structure led to several studies of the post-buckling behavior of graphite-epoxy structural components. Studies of the postbuckling behavior of flat and curved, unstiffened and stiffened graphite-epoxy panels loaded in compression and shear were summarized. The response and failure characteristics of specimens studied experimentally were described, and analytical and experimental results were compared. The specimens tested in the studies described were fabricated from commercially available 0.005-inch-thick unidirectional graphite-fiber tapes preimpregnated with 350 F cure thermosetting epoxy resins.

Title: Experimental and analytical study of frictional anisotropy of nanotubes

NASA Astrophysics Data System (ADS)

Riedo, Elisa; Gao, Yang; Li, Tai-De; Chiu, Hsiang-Chih; Kim, Suenne; Klinke, Christian; Tosatti, Erio

The frictional properties of Carbon and Boron Nitride nanotubes (NTs) are very important in a variety of applications, including composite materials, carbon fibers, and micro/nano-electromechanical systems. Atomic force microscopy (AFM) is a powerful tool to investigate with nanoscale resolution the frictional properties of individual NTs. Here, we report on an experimental study of the frictional properties of different types of supported nanotubes by AFM. We also propose a quantitative model to describe and then predict the frictional properties of nanotubes sliding on a substrate along (longitudinal friction) or perpendicular (transverse friction) their axis. This model provides a simple but general analytical relationship that well describes the acquired experimental data. As an example of potential applications, this experimental method combined with the proposed model can guide to design better NTs-ceramic composites, or to self-assemble the nanotubes on a surface in a given direction. M. Lucas et al., Nature Materials 8, 876-881 (2009).

Experimental design to evaluate directed adaptive mutation in Mammalian cells.

PubMed

Bordonaro, Michael; Chiaro, Christopher R; May, Tobias

2014-12-09

We describe the experimental design for a methodological approach to determine whether directed adaptive mutation occurs in mammalian cells. Identification of directed adaptive mutation would have profound practical significance for a wide variety of biomedical problems, including disease development and resistance to treatment. In adaptive mutation, the genetic or epigenetic change is not random; instead, the presence and type of selection influences the frequency and character of the mutation event. Adaptive mutation can contribute to the evolution of microbial pathogenesis, cancer, and drug resistance, and may become a focus of novel therapeutic interventions. Our experimental approach was designed to distinguish between 3 types of mutation: (1) random mutations that are independent of selective pressure, (2) undirected adaptive mutations that arise when selective pressure induces a general increase in the mutation rate, and (3) directed adaptive mutations that arise when selective pressure induces targeted mutations that specifically influence the adaptive response. The purpose of this report is to introduce an experimental design and describe limited pilot experiment data (not to describe a complete set of experiments); hence, it is an early report. An experimental design based on immortalization of mouse embryonic fibroblast cells is presented that links clonal cell growth to reversal of an inactivating polyadenylation site mutation. Thus, cells exhibit growth only in the presence of both the countermutation and an inducing agent (doxycycline). The type and frequency of mutation in the presence or absence of doxycycline will be evaluated. Additional experimental approaches would determine whether the cells exhibit a generalized increase in mutation rate and/or whether the cells show altered expression of error-prone DNA polymerases or of mismatch repair proteins. We performed the initial stages of characterizing our system and have limited preliminary data from several pilot experiments. Cell growth and DNA sequence data indicate that we have identified a cell clone that exhibits several suitable characteristics, although further study is required to identify a more optimal cell clone. The experimental approach is based on a quantum biological model of basis-dependent selection describing a novel mechanism of adaptive mutation. This project is currently inactive due to lack of funding. However, consistent with the objective of early reports, we describe a proposed study that has not produced publishable results, but is worthy of report because of the hypothesis, experimental design, and protocols. We outline the project's rationale and experimental design, with its strengths and weaknesses, to stimulate discussion and analysis, and lay the foundation for future studies in this field.

The Use and Interpretation of Quasi-Experimental Studies in Medical Informatics

PubMed Central

Harris, Anthony D.; McGregor, Jessina C.; Perencevich, Eli N.; Furuno, Jon P.; Zhu, Jingkun; Peterson, Dan E.; Finkelstein, Joseph

2006-01-01

Quasi-experimental study designs, often described as nonrandomized, pre-post intervention studies, are common in the medical informatics literature. Yet little has been written about the benefits and limitations of the quasi-experimental approach as applied to informatics studies. This paper outlines a relative hierarchy and nomenclature of quasi-experimental study designs that is applicable to medical informatics intervention studies. In addition, the authors performed a systematic review of two medical informatics journals, the Journal of the American Medical Informatics Association (JAMIA) and the International Journal of Medical Informatics (IJMI), to determine the number of quasi-experimental studies published and how the studies are classified on the above-mentioned relative hierarchy. They hope that future medical informatics studies will implement higher level quasi-experimental study designs that yield more convincing evidence for causal links between medical informatics interventions and outcomes. PMID:16221933

SELF-INSTRUCTIONAL SUPPLEMENTS FOR A TELEVISED PHYSICS COURSE, STUDY PLAN AND EXPERIMENTAL DESIGN.

ERIC Educational Resources Information Center

KLAUS, DAVID J.; LUMSDAINE, ARTHUR A.

THE INITIAL PHASES OF A STUDY OF SELF-INSTRUCTIONAL AIDS FOR A TELEVISED PHYSICS COURSE WERE DESCRIBED. THE APPROACH, EXPERIMENTAL DESIGN, PROCEDURE, AND TECHNICAL ASPECTS OF THE STUDY PLAN WERE INCLUDED. THE MATERIALS WERE PREPARED TO SUPPLEMENT THE SECOND SEMESTER OF HIGH SCHOOL PHYSICS. THE MATERIAL COVERED STATIC AND CURRENT ELECTRICITY,…

Methodological Concerns in Experimental Reading Research: All That Glitters...

ERIC Educational Resources Information Center

Henk, William A.

1987-01-01

Describes the nature and consequences of liberally or improperly applying the traditional reading research methodology and provides an argument for tempering judgments about the relative contributions that experimental studies make to the professional literature in reading. (SKC)

Methodological Considerations in On-Line Contingent Research and Implications for Learning. Technical Report.

ERIC Educational Resources Information Center

Whittington, Marna C.

Methods for the implementation of on-line contingent research are described in this study. In a contingent experimentation procedure, the content of successive experimental trials is a function of a subject's responses to a previous trial or trials (in contrast to traditional experimentation in which the subject is presented a previously…

Hypertonic Saline Resuscitation Restores Inflammatory Cytokine Balance in Post-Traumatic Hemorrhagic Shock Patients

DTIC Science & Technology

2004-09-01

hypertonic saline with 6% dextran-70 (HSD) has been shown in experimental studies to reduce shock/resuscitation-induced inflammatory reactions and...hemodynamics and reestablishing inflammatory equilibrium [12]. Various immunoinflammatory alterations have been described in clinical and experimental ...ultimately causing greater morbidity and mortality [4]. Moreover, convincing experimental evidence indicates that conventional large-volume fluid

Return to Our Roots: Raising Radishes to Teach Experimental Design. Methods and Techniques.

ERIC Educational Resources Information Center

Stallings, William M.

1993-01-01

Reviews research in teaching applied statistics. Concludes that students should analyze data from studies they have designed and conducted. Describes an activity in which students study germination and growth of radish seeds. Includes a table providing student instructions for both the experimental procedure and data analysis. (CFR)

Quasi-experimental study designs series-paper 7: assessing the assumptions.

PubMed

Bärnighausen, Till; Oldenburg, Catherine; Tugwell, Peter; Bommer, Christian; Ebert, Cara; Barreto, Mauricio; Djimeu, Eric; Haber, Noah; Waddington, Hugh; Rockers, Peter; Sianesi, Barbara; Bor, Jacob; Fink, Günther; Valentine, Jeffrey; Tanner, Jeffrey; Stanley, Tom; Sierra, Eduardo; Tchetgen, Eric Tchetgen; Atun, Rifat; Vollmer, Sebastian

2017-09-01

Quasi-experimental designs are gaining popularity in epidemiology and health systems research-in particular for the evaluation of health care practice, programs, and policy-because they allow strong causal inferences without randomized controlled experiments. We describe the concepts underlying five important quasi-experimental designs: Instrumental Variables, Regression Discontinuity, Interrupted Time Series, Fixed Effects, and Difference-in-Differences designs. We illustrate each of the designs with an example from health research. We then describe the assumptions required for each of the designs to ensure valid causal inference and discuss the tests available to examine the assumptions. Copyright © 2017 Elsevier Inc. All rights reserved.

Laser-Induced Molecular Fluorescence: A Physical Chemistry Experiment.

ERIC Educational Resources Information Center

Tellinghuisen, Joel

1981-01-01

Describes a companion experiment to the experimental study of the di-iodide visible absorption spectrum. Experimental details, interpretation, and data analysis are provided for an analysis of the di-iodide fluorescence excited by a visible laser, using a Raman instrument. (CS)

A survey of the alpha-nucleon interaction

NASA Astrophysics Data System (ADS)

Ali, S.; Ahmad, A. A. Z.; Ferdous, N.

1985-10-01

This paper gives a survey of the alpha-nucleon interaction and then describes experimental work on angular distributions of differential scattering cross sections and polarizations in proton-alpha and neutron-alpha scattering. The phenomenological approach, which includes the study of both local and nonlocal potentials reproducing the experimental alpha-nucleon scattering data, is discussed. Basic studies of the alpha-nucleon interaction attempting to build an interaction between an alpha particle and a nucleon from first principles are then described. The authors then present a critical discussion of the results with some concluding remarks suggesting the direction for further investigation.

A far-field radio-frequency experimental exposure system with unrestrained mice.

PubMed

Hansen, Jared W; Asif, Sajid; Singelmann, Lauren; Khan, Muhammad Saeed; Ghosh, Sumit; Gustad, Tom; Doetkott, Curt; Braaten, Benjamin D; Ewert, Daniel L

2015-01-01

Many studies have been performed on exploring the effects of radio-frequency (RF) energy on biological function in vivo. In particular, gene expression results have been inconclusive due, in part, to a lack of a standardized experimental procedure. This research describes a new far field RF exposure system for unrestrained murine models that reduces experimental error. The experimental procedure includes the materials used, the creation of a patch antenna, the uncertainty analysis of the equipment, characterization of the test room, experimental equipment used and setup, power density and specific absorption rate experiment, and discussion. The result of this research is an experimental exposure system to be applied to future biological studies.

Drosophila Melanogaster as an Experimental Organism.

ERIC Educational Resources Information Center

Rubin, Gerald M.

1988-01-01

Discusses the role of the fruit fly in genetics research requiring a multidisciplinary approach. Describes embryological and genetic methods used in the experimental analysis of this organism. Outlines the use of Drosophila in the study of the development and function of the nervous system. (RT)

Hypertonic Saline Resuscitation Restores Inflammatory Cytokine Balance in Post-Traumatic Hemorrhagic Shock Patients

DTIC Science & Technology

2004-08-01

immunocompetant cells experience bidirectional communication with hormones and cytokines [35,40]. Thus, despite compelling experimental findings, HSD has not...hypertonic saline with 6% dextran-70 (HSD) has been shown in experimental studies to reduce shock/resuscitation-induced inflammatory reactions and...alterations have been described in clinical and experimental investigations of post-traumatic hemorrhagic shock [13]. The initial immunological

Non-linear identification of a squeeze-film damper

NASA Technical Reports Server (NTRS)

Stanway, Roger; Mottershead, John; Firoozian, Riaz

1987-01-01

Described is an experimental study to identify the damping laws associated with a squeeze-film vibration damper. This is achieved by using a non-linear filtering algorithm to process displacement responses of the damper ring to synchronous excitation and thus to estimate the parameters in an nth-power velocity model. The experimental facility is described in detail and a representative selection of results is included. The identified models are validated through the prediction of damper-ring orbits and comparison with observed responses.

The remarkable story of the partial cutting study at the Dukes Experimental Forest

Treesearch

Laura S. Kenefic; Christel C. Kern

2013-01-01

This paper describes our recent and successful efforts to reopen the pioneering U.S. Forest Service "Partial Cutting Study" on the Dukes Experimental Forest in Michigan. This experiment in northern hardwood silviculture was initiated in 1926 and closed in 1966. Although the research conducted there informed the use of uneven-aged silviculture throughout the...

Proceedings of the Missouri Ozark Forest Ecosystem Project Symposium: an experimental approach to landscape research

Treesearch

Brian L. Brookshire; Stephen R., eds. Shifley

1997-01-01

Describes the Missouri Ozark Forest Ecosystem Projects (MOFEP) that was initiated in 1991 in southeastern Missouri. Describes in detail the coordinated research studies examining vegetation dynamics, down wood, fungi, birds, small mammals, herpetofauna, invertebrates, and genetics. Soils, geolandforms, ecological landtypes, and climate at the sites are described....

Senecio grisebachii Baker: Pyrrolizidine alkaloids and experimental poisoning in calves

USDA-ARS?s Scientific Manuscript database

The main objectives of this study were to determine the 1,2-dehydropyrrolizidine alkaloid (DHPA) content in Senecio grisebachii Baker (Compositae), to experimentally demonstrate its toxicity in calves and to describe the main clinical and pathological findings of this toxicity. S. grisebachii plants...

Experimental and numerical investigations of sedimentation of porous wastewater sludge flocs.

PubMed

Hriberšek, M; Zajdela, B; Hribernik, A; Zadravec, M

2011-02-01

The paper studies the properties and sedimentation characteristics of sludge flocs, as they appear in biological wastewater treatment (BWT) plants. The flocs are described as porous and permeable bodies, with their properties defined based on conducted experimental study. The derivation is based on established geometrical properties, high-speed camera data on settling velocities and non-linear numerical model, linking settling velocity with physical properties of porous flocs. The numerical model for derivation is based on generalized Stokes model, with permeability of the floc described by the Brinkman model. As a result, correlation for flocs porosity is obtained as a function of floc diameter. This data is used in establishing a CFD numerical model of sedimentation of flocs in test conditions, as recorded during experimental investigation. The CFD model is based on Euler-Lagrange formulation, where the Lagrange formulation is chosen for computation of flocs trajectories during sedimentation. The results of numerical simulations are compared with experimental results and very good agreement is observed. © 2010 Elsevier Ltd. All rights reserved.

Studying 3D Collisions with Smartphones

ERIC Educational Resources Information Center

Pereira, Vanda; Martin-Ramos, Pablo; da Silva, Pedro Pereira; Silva, Manuela Ramos

2017-01-01

This paper describes a conservation of momentum experiment using just smartphones and two beach balls, thus making the experimental study of this movement available to any classroom. For a more thorough analysis of the data, a computer can also be used. Experiments making use of smartphone sensors have been described before, contributing to an…

A systematic review and meta-analysis of the efficacy of piracetam and piracetam-like compounds in experimental stroke.

PubMed

Wheble, Philippa C R; Sena, Emily S; Macleod, Malcolm R

2008-01-01

Piracetam was a candidate neuroprotective drug for acute stroke ineffective in clinical trial. Here we use systematic review and meta-analysis to describe the evidence supporting a protective effect of piracetam and its derivatives in animal models of stroke. We present a systematic review of reports describing the use of piracetam and its derivatives in animal models of focal ischaemia, where the outcome was measured as an infarct size or neurological score (Der Simonian and Laird random effects meta-analysis). Only 2 studies, published 10 years after the first clinical trial of piracetam had been initiated, described its efficacy in animal models of stroke. A further 4 studies described the efficacy of related compounds. Piracetam and its derivatives improved the outcome by 30.2% (95% CI = 16.1-44.4). The median study quality was 4/10 (inter-quartile range = 4-6). Piracetam and its derivatives demonstrate neuroprotective efficacy in experimental stroke, but our findings raise concerns about the amount of available data, the quality of the studies and publication bias. (c) 2007 S. Karger AG, Basel.

Magnetohydrodynamic generator experimental studies

NASA Technical Reports Server (NTRS)

Pierson, E. S.

1972-01-01

The results for an experimental study of a one wavelength MHD induction generator operating on a liquid flow are presented. First the design philosophy and the experimental generator design are summarized, including a description of the flow loop and instrumentation. Next a Fourier series method of treating the fact that the magnetic flux density produced by the stator is not a pure traveling sinusoid is described and some results summarized. This approach appears to be of interest after revisions are made, but the initial results are not accurate. Finally, some of the experimental data is summarized for various methods of excitation.

A numerical and experimental study of three-dimensional liquid sloshing in a rotating spherical container

NASA Technical Reports Server (NTRS)

Chen, Kuo-Huey; Kelecy, Franklyn J.; Pletcher, Richard H.

1992-01-01

A numerical and experimental study of three dimensional liquid sloshing inside a partially-filled spherical container undergoing an orbital rotating motion is described. Solutions of the unsteady, three-dimensional Navier-Stokes equations for the case of a gradual spin-up from rest are compared with experimental data obtained using a rotating test rig fitted with two liquid-filled spherical tanks. Data gathered from several experiments are reduced in terms of a dimensionless free surface height for comparison with transient results from the numerical simulations. The numerical solutions are found to compare favorably with the experimental data.

Kinetics of conjugative gene transfer on surfaces in granular porous media

NASA Astrophysics Data System (ADS)

Massoudieh, A.; Crain, C.; Lambertini, E.; Nelson, K. E.; Barkouki, T.; L'Amoreaux, P.; Loge, F. J.; Ginn, T. R.

2010-03-01

The transfer of genetic material among bacteria in the environment can occur both in the planktonic and attached state. Given the propensity of organisms to exist in sessile microbial communities in oligotrophic subsurface conditions, and that such conditions typify the subsurface, this study focuses on exploratory modeling of horizontal gene transfer among surface-associated Escherichiacoli in the subsurface. The mathematics so far used to describe the kinetics of conjugation in biofilms are developed largely from experimental observations of planktonic gene transfer, and are absent of lags or plasmid stability that appear experimentally. We develop a model and experimental system to quantify bacterial filtration and gene transfer in the attached state, on granular porous media. We include attachment kinetics described in Nelson et al. (2007) using the filtration theory approach of Nelson and Ginn (2001, 2005) with motility of E. coli described according to Biondi et al. (1998).

Study of Interaction of Reinforcement with Concrete by Numerical Methods

NASA Astrophysics Data System (ADS)

Tikhomirov, V. M.; Samoshkin, A. S.

2018-01-01

This paper describes the study of deformation of reinforced concrete. A mathematical model for the interaction of reinforcement with concrete, based on the introduction of a contact layer, whose mechanical characteristics are determined from the experimental data, is developed. The limiting state of concrete is described using the Drucker-Prager theory and the fracture criterion with respect to maximum plastic deformations. A series of problems of the theory of reinforced concrete are solved: stretching of concrete from a central-reinforced prism and pre-stressing of concrete. It is shown that the results of the calculations are in good agreement with the experimental data.

Patch enlargement of the aortic and mitral valve rings with aortic and mitral double valve replacement. Experimental study.

PubMed

Manouguian, S; Abu-Aishah, N; Neitzel, J

1979-09-01

The experimental results of patch enlargement of the aortic and mitral valve rings with aortic and mitral double valve replacement are reported. The operative technique of this new surgical method is described and the indications are discussed.

Experimental forests and ranges. Field research facilities of the Pacific Southwest Research Station.

Treesearch

Neil H. Berg

1990-01-01

The 10 experimental forests and ranges in California administered by the Pacific Southwest Research Station, Forest Service, U.S. Department of Agriculture, are described. The purposes of these facilities, and how to request their use for approved scientific study are given, and the natural resource base, data bases, studies, and general features of each are also...

Site productivity and diversity of the Middle Mountain long-term soil productivity study, West Virginia: Pre-experimental site characterization

Treesearch

Mary Beth Adams

2018-01-01

To better understand the impacts of a changing environment and interactions with forest management options for forest resources, including soil, large long-term experiments are required. Such experiments require careful documentation of reference or pre-experimental conditions. This publication describes the Middle Mountain Long-term Soil Productivity (LTSP) Study,...

Flexible manipulator control experiments and analysis

NASA Technical Reports Server (NTRS)

Yurkovich, S.; Ozguner, U.; Tzes, A.; Kotnik, P. T.

1987-01-01

Modeling and control design for flexible manipulators, both from an experimental and analytical viewpoint, are described. From the application perspective, an ongoing effort within the laboratory environment at the Ohio State University, where experimentation on a single link flexible arm is underway is described. Several unique features of this study are described here. First, the manipulator arm is slewed by a direct drive dc motor and has a rigid counterbalance appendage. Current experimentation is from two viewpoints: (1) rigid body slewing and vibration control via actuation with the hub motor, and (2) vibration suppression through the use of structure-mounted proof-mass actuation at the tip. Such an application to manipulator control is of interest particularly in design of space-based telerobotic control systems, but has received little attention to date. From an analytical viewpoint, parameter estimation techniques within the closed-loop for self-tuning adaptive control approaches are discussed. Also introduced is a control approach based on output feedback and frequency weighting to counteract effects of spillover in reduced-order model design. A model of the flexible manipulator based on experimental measurements is evaluated for such estimation and control approaches.

Heat and mass transfer in wooden dowels during a simulated fire: an experimental and analytical study

Treesearch

J. A. Mardini; A. S. Lavine; V. K. Dhir

1996-01-01

Abstract--An experimental and analytical study of heat and mass transfer in wooden dowels during a simulated fire is presented in this paper. The goal of this study is to understand the processes of heat and mass transfer in wood during wildland fires. A mathematical model is developed to describe the processes of heating, drying and pyrolysis of wood until ignition...

Experimental study of high density foods for the Space Operations Center

NASA Technical Reports Server (NTRS)

Ahmed, S. M.

1981-01-01

The experimental study of high density foods for the Space Operations Center is described. A sensory evaluation of the high density foods was conducted first to test the acceptability of the products. A shelf-life study of the high density foods was also conducted for three different time lengths at three different temperatures. The nutritional analysis of the high density foods is at present incomplete.

Boundary Layer Studies on a Spinning Tangent-Ogive-Cylinder Model

DTIC Science & Technology

1975-07-01

ca) An experimental investigation of the Magnus effect on a seven caliber tangent-I ;’ ogive- cylinder model in supersonic flow is reported. The...necessary and Identify by block number) Three-Dimiensional Boundary Layer Compressible Flow Body of Revolution Magnus Effects Boundary Layer...factors have resulted in renewed interest in the study of the Magnus effect . This report describes an experimental study of the effects of spin on

A fluctuation-induced plasma transport diagnostic based upon fast-Fourier transform spectral analysis

NASA Technical Reports Server (NTRS)

Powers, E. J.; Kim, Y. C.; Hong, J. Y.; Roth, J. R.; Krawczonek, W. M.

1978-01-01

A diagnostic, based on fast Fourier-transform spectral analysis techniques, that provides experimental insight into the relationship between the experimentally observable spectral characteristics of the fluctuations and the fluctuation-induced plasma transport is described. The model upon which the diagnostic technique is based and its experimental implementation is discussed. Some characteristic results obtained during the course of an experimental study of fluctuation-induced transport in the electric field dominated NASA Lewis bumpy torus plasma are presented.

Evaluating E-Training for Public Library Staff: A Quasi-Experimental Investigation

ERIC Educational Resources Information Center

Dalston, Teresa

2009-01-01

A comparative evaluation framework of instructional interventions for implementation of online training for public library staff would enable a better understanding of how to improve the effectiveness, efficiency and efficacy of training in certain training environments. This dissertation describes a quasi-experimental study of a two-week,…

Experimental investigation of the physical properties of medium and heavy oils, their vaporization and use in explosion engines. Part III

NASA Technical Reports Server (NTRS)

Heinlein, Fritz

1926-01-01

The test equipment for studying the vaporization of heavy and medium oils is described as well as some of the experimental properties explored such as vaporization speed and diffusion coefficient. The experiemtal arrangement is also discussed.

A Simplified Experimental Scheme for the Study of Mitosis.

ERIC Educational Resources Information Center

Gill, John

1980-01-01

A procedure is described for providing preparations of dividing cells from root apical meristems, requiring only inexpensive equipment and minimal experimental skill, and using 8-Hydroxyquinoline and Toluidene-blue as a chromosome stain. The method has been sucessfully tested in schools and yields permanent preparations of adequate quality for…

EXPERIMENTAL INVESTIGATIONS OF FINE PARTICLE CHARGING BY UNIPOLAR IONS: A REVIEW

EPA Science Inventory

The paper gives results of a study relating experimental data to many theories that have been offered in attempts to describe accurately the rate of charge accumulation of fine particles in a unipolar field. The data are reviewed and compiled, and additional particle charging exp...

Intoxicação experimental por Niedenzuella stannea (Malpighiaceae) em ovinos

USDA-ARS?s Scientific Manuscript database

Niedenzuella stannea a sodium monofluoroacetate-containing plant cause of sudden death in cattle in southern Mato Grosso State. This study describes the toxicity and clinical and pathological findings of experimental poisoning by N. stannea in sheep. Fruits, mature leaves and young leaves of the pla...

Real-time Electrophysiology: Using Closed-loop Protocols to Probe Neuronal Dynamics and Beyond

PubMed Central

Linaro, Daniele; Couto, João; Giugliano, Michele

2015-01-01

Experimental neuroscience is witnessing an increased interest in the development and application of novel and often complex, closed-loop protocols, where the stimulus applied depends in real-time on the response of the system. Recent applications range from the implementation of virtual reality systems for studying motor responses both in mice1 and in zebrafish2, to control of seizures following cortical stroke using optogenetics3. A key advantage of closed-loop techniques resides in the capability of probing higher dimensional properties that are not directly accessible or that depend on multiple variables, such as neuronal excitability4 and reliability, while at the same time maximizing the experimental throughput. In this contribution and in the context of cellular electrophysiology, we describe how to apply a variety of closed-loop protocols to the study of the response properties of pyramidal cortical neurons, recorded intracellularly with the patch clamp technique in acute brain slices from the somatosensory cortex of juvenile rats. As no commercially available or open source software provides all the features required for efficiently performing the experiments described here, a new software toolbox called LCG5 was developed, whose modular structure maximizes reuse of computer code and facilitates the implementation of novel experimental paradigms. Stimulation waveforms are specified using a compact meta-description and full experimental protocols are described in text-based configuration files. Additionally, LCG has a command-line interface that is suited for repetition of trials and automation of experimental protocols. PMID:26132434

Computer modeling of electrical performance of detonators

DOE Office of Scientific and Technical Information (OSTI.GOV)

Furnberg, C.M.; Peevy, G.R.; Brigham, W.P.

1995-05-01

An empirical model of detonator electrical performance which describes the resistance of the exploding bridgewire (EBW) or exploding foil initiator (EFI or slapper) as a function of energy, deposition will be described. This model features many parameters that can be adjusted to obtain a close fit to experimental data. This has been demonstrated using recent experimental data taken with the cable discharge system located at Sandia National Laboratories. This paper will be a continuation of the paper entitled ``Cable Discharge System for Fundamental Detonator Studies`` presented at the 2nd NASA/DOD/DOE Pyrotechnic Workshop.

Cooling molten salt reactors using "gas-lift"

NASA Astrophysics Data System (ADS)

Zitek, Pavel; Valenta, Vaclav; Klimko, Marek

2014-08-01

This study briefly describes the selection of a type of two-phase flow, suitable for intensifying the natural flow of nuclear reactors with liquid fuel - cooling mixture molten salts and the description of a "Two-phase flow demonstrator" (TFD) used for experimental study of the "gas-lift" system and its influence on the support of natural convection. The measuring device and the application of the TDF device is described. The work serves as a model system for "gas-lift" (replacing the classic pump in the primary circuit) for high temperature MSR planned for hydrogen production. An experimental facility was proposed on the basis of which is currently being built an experimental loop containing the generator, separator bubbles and necessary accessories. This loop will model the removal of gaseous fission products and tritium. The cleaning of the fuel mixture of fluoride salts eliminates problems from Xenon poisoning in classical reactors.

A fast field-cycling device for high-resolution NMR: Design and application to spin relaxation and hyperpolarization experiments

NASA Astrophysics Data System (ADS)

Kiryutin, Alexey S.; Pravdivtsev, Andrey N.; Ivanov, Konstantin L.; Grishin, Yuri A.; Vieth, Hans-Martin; Yurkovskaya, Alexandra V.

2016-02-01

A device for performing fast magnetic field-cycling NMR experiments is described. A key feature of this setup is that it combines fast switching of the external magnetic field and high-resolution NMR detection. The field-cycling method is based on precise mechanical positioning of the NMR probe with the mounted sample in the inhomogeneous fringe field of the spectrometer magnet. The device enables field variation over several decades (from 100 μT up to 7 T) within less than 0.3 s; progress in NMR probe design provides NMR linewidths of about 10-3 ppm. The experimental method is very versatile and enables site-specific studies of spin relaxation (NMRD, LLSs) and spin hyperpolarization (DNP, CIDNP, and SABRE) at variable magnetic field and at variable temperature. Experimental examples of such studies are demonstrated; advantages of the experimental method are described and existing challenges in the field are outlined.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Perl, M.L.

This paper is based upon lectures in which I have described and explored the ways in which experimenters can try to find answers, or at least clues toward answers, to some of the fundamental questions of elementary particle physics. All of these experimental techniques and directions have been discussed fully in other papers, for example: searches for heavy charged leptons, tests of quantum chromodynamics, searches for Higgs particles, searches for particles predicted by supersymmetric theories, searches for particles predicted by technicolor theories, searches for proton decay, searches for neutrino oscillations, monopole searches, studies of low transfer momentum hadron physics atmore » very high energies, and elementary particle studies using cosmic rays. Each of these subjects requires several lectures by itself to do justice to the large amount of experimental work and theoretical thought which has been devoted to these subjects. My approach in these tutorial lectures is to describe general ways to experiment beyond the standard model. I will use some of the topics listed to illustrate these general ways. Also, in these lectures I present some dreams and challenges about new techniques in experimental particle physics and accelerator technology, I call these Experimental Needs. 92 references.« less

Knowledge synthesis with maps of neural connectivity.

PubMed

Tallis, Marcelo; Thompson, Richard; Russ, Thomas A; Burns, Gully A P C

2011-01-01

This paper describes software for neuroanatomical knowledge synthesis based on neural connectivity data. This software supports a mature methodology developed since the early 1990s. Over this time, the Swanson laboratory at USC has generated an account of the neural connectivity of the sub-structures of the hypothalamus, amygdala, septum, hippocampus, and bed nucleus of the stria terminalis. This is based on neuroanatomical data maps drawn into a standard brain atlas by experts. In earlier work, we presented an application for visualizing and comparing anatomical macro connections using the Swanson third edition atlas as a framework for accurate registration. Here we describe major improvements to the NeuARt application based on the incorporation of a knowledge representation of experimental design. We also present improvements in the interface and features of the data mapping components within a unified web-application. As a step toward developing an accurate sub-regional account of neural connectivity, we provide navigational access between the data maps and a semantic representation of area-to-area connections that they support. We do so based on an approach called "Knowledge Engineering from Experimental Design" (KEfED) model that is based on experimental variables. We have extended the underlying KEfED representation of tract-tracing experiments by incorporating the definition of a neuronanatomical data map as a measurement variable in the study design. This paper describes the software design of a web-application that allows anatomical data sets to be described within a standard experimental context and thus indexed by non-spatial experimental design features.

Experimental and analytical studies for the NASA carbon fiber risk assessment

NASA Technical Reports Server (NTRS)

1980-01-01

Various experimental and analytical studies performed for the NASA carbon fiber risk assessment program are described with emphasis on carbon fiber characteristics, sensitivity of electrical equipment and components to shorting or arcing by carbon fibers, attenuation effect of carbon fibers on aircraft landing aids, impact of carbon fibers on industrial facilities. A simple method of estimating damage from airborne carbon fibers is presented.

An experimental study of unsteady sprays at very high injection pressures

NASA Astrophysics Data System (ADS)

Reggiori, A.; Mariani, F.; Parigi, G.; Carlevaro, R.

An experimental study of the development of fuel sprays under very high injection pressures is described. A gas gun capable of generating pressure pulses up to 10,000 bar has been employed as an injection pump. Tests have been carried out with simple cylindrical nozzles, injecting diesel oil in ambient air. The development of the jet has been visualized by means of flash shadowgraphy.

A Study in Competition

ERIC Educational Resources Information Center

Payne, Therese Anne

1973-01-01

Describes a microbiological experiment designed to study the competition between two species of bacteria. Experimental procedures and data obtained in conducting this experiment are provided, together with a discussion of the results. (JR)

The Impact of Goal Setting on Team Simulation Experience.

ERIC Educational Resources Information Center

Fandt, Patricia M.; And Others

1990-01-01

Describes a study that examined the effects of goal setting on undergraduate students competing in a computerized business simulation. Group cohesiveness is discussed, treatments for the experimental and control groups are described, perceived team success is measured, and team simulation performance is evaluated. (30 references) (LRW)

Psychological Interventions to Facilitate Employment Outcomes for Cancer Survivors: A Systematic Review and Meta-Analysis

ERIC Educational Resources Information Center

Fong, Carlton J.; Murphy, Kathleen M.; Westbrook, John D.; Markle, Minda M.

2018-01-01

Purpose: The objective was to examine experimental and quasi-experimental studies about interventions that (i) included behavioral, psychological, educational, or vocational components; (ii) involved cancer survivors aged 18 years or older; and (iii) assessed employment outcomes. Methods: The aims were both to describe the variety of interventions…

Experimental Study of Sudden Solidification of Supercooled Water

ERIC Educational Resources Information Center

Bochnícek, Zdenek

2014-01-01

The two independent methods of measurement of the mass of ice created at sudden solidification of supercooled water are described. One is based on the calorimetric measurement of heat that is necessary for melting the ice and the second interprets the volume change that accompanies the water freezing. Experimental results are compared with the…

Unpacking the Hidden Efficacies of Learning in Productive Failure

ERIC Educational Resources Information Center

Hung, David; Chen, Victor; Lim, Seo Hong

2009-01-01

This paper describes a framework for learning where learners undergo experimentations with the phenomena at hand according to progressive and staged goals. Bowling is used as a case study in this paper. The premise for experimentations is that learners can experience hidden efficacies, including the formation of "bad habits." A distinction is made…

Development of an Experimental Literacy Assessment Battery. Final Report.

ERIC Educational Resources Information Center

Sticht, Thomas G.; Beck, Lawrence J.

This report describes the development of a Literacy Assessment Battery (LAB) for determining the relative efficiency with which adults can comprehend language by reading or listening. Development of the LAB included: the tryout with adults of two listening and reading tests designed for children; experimental studies of a decoding task involving…

Recent mouse and rat methods for the study of experimental oral candidiasis.

PubMed

Costa, Anna C B P; Pereira, Cristiane A; Junqueira, Juliana C; Jorge, Antonio O C

2013-07-01

The Candida genus expresses virulence factors that, when combined with immunosuppression and other risk factors, can cause different manifestations of oral candidiasis. The treatment of mucosal infections caused by Candida and the elucidation of the disease process have proven challenging. Therefore, the study of experimentally induced oral candidiasis in rats and mice is useful to clarify the etiopathology of this condition, improve diagnosis, and search for new therapeutic options because the disease process in these animals is similar to that of human candidiasis lesions. Here, we describe and discuss new studies involving rat and mouse models of oral candidiasis with respect to methods for inducing experimental infection, methods for evaluating the development of experimental candidiasis, and new treatment strategies for oral candidiasis.

A Meta-Evaluation of Nutrition Education Intervention Research among Pregnant Women.

ERIC Educational Resources Information Center

Boyd, Neal Richard, Jr.; Windsor, Richard A.

1993-01-01

Meta-analysis of five studies advocating nutrition education for pregnant women led to recommendations for research: (1) define nutrition education to aid replication; (2) describe the intervention thoroughly; (3) use experimental designs; (4) collect follow-up data; and (5) describe baseline demographic, behavioral, and health characteristics of…

Formation and emission mechanisms of Ag nanoclusters in the Ar matrix assembly cluster source

NASA Astrophysics Data System (ADS)

Zhao, Junlei; Cao, Lu; Palmer, Richard E.; Nordlund, Kai; Djurabekova, Flyura

2017-11-01

In this paper, we study the mechanisms of growth of Ag nanoclusters in a solid Ar matrix and the emission of these nanoclusters from the matrix by a combination of experimental and theoretical methods. The molecular dynamics simulations show that the cluster growth mechanism can be described as "thermal spike-enhanced clustering" in multiple sequential ion impact events. We further show that experimentally observed large sputtered metal clusters cannot be formed by direct sputtering of Ag mixed in the Ar. Instead, we describe the mechanism of emission of the metal nanocluster that, at first, is formed in the cryogenic matrix due to multiple ion impacts, and then is emitted as a result of the simultaneous effects of interface boiling and spring force. We also develop an analytical model describing this size-dependent cluster emission. The model bridges the atomistic simulations and experimental time and length scales, and allows increasing the controllability of fast generation of nanoclusters in experiments with a high production rate.

Jet Fuel Exacerbated Noise-Induced Hearing Loss: Focus on Prediction of Central Auditory Processing Dysfunction

DTIC Science & Technology

2017-09-01

to develop a multi-scale model, together with relevant supporting experimental data, to describe jet fuel exacerbated noise induced hearing loss. In...scale model, together with relevant supporting experimental data, to describe jet fuel exacerbated noise-induced hearing loss. Such hearing loss...project was to develop a multi-scale model, together with relevant supporting experimental data, to describe jet fuel exacerbated NIHL. Herein we

Are the Color Gamuts of CRT and LCD Triangular? An Experimental Study

DTIC Science & Technology

2000-07-01

UNCLASSIFIED Defense Technical Information Center Compilation Part Notice ADPO113 31 TITLE: Are the Color Gamuts of CRT and LCD Triangular? An...ADP011297 thru ADP011332 UNCLASSIFIED Are the Color Gamuts of CRT and LCD Triangular? An Experimental Study Guan-wei Leea and Chao-hua Wenb aDepartment of...Tube) display. This study describes the difference of color gamuts in different luminance level and the accuracy of color between CRT and LCD. In the

Dynamic wind-tunnel testing of active controls by the NASA Langley Research Center

NASA Technical Reports Server (NTRS)

Abel, I.; Doggett, R. V.; Newsom, J. R.; Sandford, M.

1984-01-01

Dynamic wind-tunnel testing of active controls by the NASA Langley Research Center is presented. Seven experimental studies that were accomplished to date are described. Six of the studies focus on active flutter suppression. The other focuses on active load alleviation. In addition to presenting basic results for these experimental studies, topics including model design and construction, control law synthesis, active control system implementation, and wind-tunnel test techniques are discussed.

T- P Phase Diagram of Nitrogen at High Pressures

NASA Astrophysics Data System (ADS)

Algul, G.; Enginer, Y.; Yurtseven, H.

2018-05-01

By employing a mean field model, calculation of the T- P phase diagram of molecular nitrogen is performed at high pressures up to 200 GPa. Experimental data from the literature are used to fit a quadratic function in T and P, describing the phase line equations which have been derived using the mean field model studied here for N 2, and the fitted parameters are determined. Our model study gives that the observed T- P phase diagram can be described satisfactorily for the first-order transitions between the phases at low as well as high pressures in nitrogen. Some thermodynamic quantities can also be predicted as functions of temperature and pressure from the mean field model studied here and they can be compared with the experimental data.

Experiments in ultrasonic flaw detection using a MEMS transducer

NASA Astrophysics Data System (ADS)

Jain, Akash; Greve, David W.; Oppenheim, Irving J.

2003-08-01

In earlier work we developed a MEMS phased array transducer, fabricated in the MUMPs process, and we reported on initial experimental studies in which the device was affixed into contact with solids. We demonstrated the successful detection of signals from a conventional ultrasonic source, and the successful localization of the source in an off-axis geometry using phased array signal processing. We now describe the predicted transmission and coupling characteristics for such devices in contact with solids, demonstrating reasonable agreement with experimental behavior. We then describe the results of flaw detection experiments, as well as results for fluid-coupled detectors.

Learning and memory in zebrafish larvae

PubMed Central

Roberts, Adam C.; Bill, Brent R.; Glanzman, David L.

2013-01-01

Larval zebrafish possess several experimental advantages for investigating the molecular and neural bases of learning and memory. Despite this, neuroscientists have only recently begun to use these animals to study memory. However, in a relatively short period of time a number of forms of learning have been described in zebrafish larvae, and significant progress has been made toward their understanding. Here we provide a comprehensive review of this progress; we also describe several promising new experimental technologies currently being used in larval zebrafish that are likely to contribute major insights into the processes that underlie learning and memory. PMID:23935566

Experimental Forests and climate change: views of long-term employees on ecological change and the role of Experimental Forests and Ranges in understanding and adapting to climate change

Treesearch

Laurie Yung; Mason Bradbury; Daniel R. Williams

2012-01-01

In this project, we examined the views of 21 long-term employees on climate change in 14 Rocky Mountain Research Station Experimental Forests and Ranges (EFRs). EFRs were described by employees as uniquely positioned to advance knowledge of climate change impacts and adaptation strategies due to the research integrity they provide for long-term studies, the ability to...

Knowledge Synthesis with Maps of Neural Connectivity

PubMed Central

Tallis, Marcelo; Thompson, Richard; Russ, Thomas A.; Burns, Gully A. P. C.

2011-01-01

This paper describes software for neuroanatomical knowledge synthesis based on neural connectivity data. This software supports a mature methodology developed since the early 1990s. Over this time, the Swanson laboratory at USC has generated an account of the neural connectivity of the sub-structures of the hypothalamus, amygdala, septum, hippocampus, and bed nucleus of the stria terminalis. This is based on neuroanatomical data maps drawn into a standard brain atlas by experts. In earlier work, we presented an application for visualizing and comparing anatomical macro connections using the Swanson third edition atlas as a framework for accurate registration. Here we describe major improvements to the NeuARt application based on the incorporation of a knowledge representation of experimental design. We also present improvements in the interface and features of the data mapping components within a unified web-application. As a step toward developing an accurate sub-regional account of neural connectivity, we provide navigational access between the data maps and a semantic representation of area-to-area connections that they support. We do so based on an approach called “Knowledge Engineering from Experimental Design” (KEfED) model that is based on experimental variables. We have extended the underlying KEfED representation of tract-tracing experiments by incorporating the definition of a neuronanatomical data map as a measurement variable in the study design. This paper describes the software design of a web-application that allows anatomical data sets to be described within a standard experimental context and thus indexed by non-spatial experimental design features. PMID:22053155

The Motive to Avoid Success Studied as a Function of Sex, Age, and Sex of Cue Variables.

ERIC Educational Resources Information Center

Talcott, Lou Ann W.

This thesis describes an experimental study of the "motive to avoid success," as described by Matina Horner (1968), using sex, age, and sex of cues as independent variables. School-aged subjects (5th, 8th, 11th grade and college students) wrote stories in response to one of two written thematic apperceptive cues. The dependent measure was the…

Verb Form Indicates Discourse Segment Type in Biological Research Papers: Experimental Evidence

ERIC Educational Resources Information Center

de Waard, Anita; Maat, Henk Pander

2012-01-01

Corpus studies suggest that verb tense is a differentiating feature between, on the one hand, text pertaining to experimental results (involving methods and results) and on the other hand, text pertaining to more abstract concepts (i.e. regarding background knowledge in a field, hypotheses, problems or claims). In this paper, we describe a user…

Utilization of a Microcomputer for the Study of an Iodine Oxidation and Equilibrium Reaction: A Physical Chemistry Experiment.

ERIC Educational Resources Information Center

Julien, L. M.

1984-01-01

Describes a physical chemistry experiment which incorporates the use of a microcomputer to enhance understanding of combined kinetic and equilibrium phenomena, to increase experimental capabilities when working with large numbers of students and limited equipment, and for the student to develop a better understanding of experimental design. (JN)

Advances in rapid compression machine studies of low- and intermediate-temperature autoignition phenomena

DOE PAGES

Goldsborough, S. Scott; Hochgreb, Simone; Vanhove, Guillaume; ...

2017-07-10

Rapid compression machines (RCMs) are widely-used to acquire experimental insights into fuel autoignition and pollutant formation chemistry, especially at conditions relevant to current and future combustion technologies. RCM studies emphasize important experimental regimes, characterized by low- to intermediate-temperatures (600–1200 K) and moderate to high pressures (5–80 bar). At these conditions, which are directly relevant to modern combustion schemes including low temperature combustion (LTC) for internal combustion engines and dry low emissions (DLE) for gas turbine engines, combustion chemistry exhibits complex and experimentally challenging behaviors such as the chemistry attributed to cool flame behavior and the negative temperature coefficient regime. Challengesmore » for studying this regime include that experimental observations can be more sensitive to coupled physical-chemical processes leading to phenomena such as mixed deflagrative/autoignitive combustion. Experimental strategies which leverage the strengths of RCMs have been developed in recent years to make RCMs particularly well suited for elucidating LTC and DLE chemistry, as well as convolved physical-chemical processes. Specifically, this work presents a review of experimental and computational efforts applying RCMs to study autoignition phenomena, and the insights gained through these efforts. A brief history of RCM development is presented towards the steady improvement in design, characterization, instrumentation and data analysis. Novel experimental approaches and measurement techniques, coordinated with computational methods are described which have expanded the utility of RCMs beyond empirical studies of explosion limits to increasingly detailed understanding of autoignition chemistry and the role of physical-chemical interactions. Fundamental insight into the autoignition chemistry of specific fuels is described, demonstrating the extent of knowledge of low-temperature chemistry derived from RCM studies, from simple hydrocarbons to multi-component blends and full-boiling range fuels. In conclusion, emerging needs and further opportunities are suggested, including investigations of under-explored fuels and the implementation of increasingly higher fidelity diagnostics.« less

Advances in rapid compression machine studies of low- and intermediate-temperature autoignition phenomena

DOE Office of Scientific and Technical Information (OSTI.GOV)

Goldsborough, S. Scott; Hochgreb, Simone; Vanhove, Guillaume

Rapid compression machines (RCMs) are widely-used to acquire experimental insights into fuel autoignition and pollutant formation chemistry, especially at conditions relevant to current and future combustion technologies. RCM studies emphasize important experimental regimes, characterized by low- to intermediate-temperatures (600–1200 K) and moderate to high pressures (5–80 bar). At these conditions, which are directly relevant to modern combustion schemes including low temperature combustion (LTC) for internal combustion engines and dry low emissions (DLE) for gas turbine engines, combustion chemistry exhibits complex and experimentally challenging behaviors such as the chemistry attributed to cool flame behavior and the negative temperature coefficient regime. Challengesmore » for studying this regime include that experimental observations can be more sensitive to coupled physical-chemical processes leading to phenomena such as mixed deflagrative/autoignitive combustion. Experimental strategies which leverage the strengths of RCMs have been developed in recent years to make RCMs particularly well suited for elucidating LTC and DLE chemistry, as well as convolved physical-chemical processes. Specifically, this work presents a review of experimental and computational efforts applying RCMs to study autoignition phenomena, and the insights gained through these efforts. A brief history of RCM development is presented towards the steady improvement in design, characterization, instrumentation and data analysis. Novel experimental approaches and measurement techniques, coordinated with computational methods are described which have expanded the utility of RCMs beyond empirical studies of explosion limits to increasingly detailed understanding of autoignition chemistry and the role of physical-chemical interactions. Fundamental insight into the autoignition chemistry of specific fuels is described, demonstrating the extent of knowledge of low-temperature chemistry derived from RCM studies, from simple hydrocarbons to multi-component blends and full-boiling range fuels. In conclusion, emerging needs and further opportunities are suggested, including investigations of under-explored fuels and the implementation of increasingly higher fidelity diagnostics.« less

High-pressure Experimental Studies on Geo-liquids Using Synchrotron Radiation at the Advanced Photon Source

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wang, Yanbin; Shen, Guoyin

2014-12-23

Here, we review recent progress in studying silicate, carbonate, and metallic liquids of geological and geophysical importance at high pressure and temperature, using the large-volume high-pressure devices at the third-generation synchrotron facility of the Advanced Photon Source, Argonne National Laboratory. These integrated high-pressure facilities now offer a unique combination of experimental techniques that allow researchers to investigate structure, density, elasticity, viscosity, and interfacial tension of geo-liquids under high pressure, in a coordinated and systematic fashion. Moreover, we describe experimental techniques, along with scientific highlights. Future developments are also discussed.

Histopathological study of experimental and natural infections by Trypanosoma cruzi in Didelphis marsupialis.

PubMed

Araujo Carreira, J C; Jansen, A M; Deane, M P; Lenzi, H L

1996-01-01

Didelphis marsupialis, the most important sylvatic reservoir of Trypanosoma cruzi, can also maintain in their anal scent glands the multiplicative forms only described in the intestinal tract of triatomine bugs. A study of 21 experimentally and 10 naturally infected opossums with T. cruzi was undertaken in order to establish the histopathological pattern under different conditions. Our results showed that the inflammation was predominantly lymphomacrophagic and more severe in the naturally infected animals but never as intense as those described in Chagas' disease or in other animal models. The parasitism in both groups was always mild with very scarce amastigote nests in the tissues. In the experimentally infected animals, the inflammation was directly related to the presence of amastigotes nests. Four 24 days-old animals, still in embryonic stage, showed multiple amastigotes nests and moderate inflammatory reactions, but even so they survived longer and presented less severe lesions than experimentally infected adult mice. Parasites were found in smooth, cardiac and/or predominantly striated muscles, as well as in nerve cells. Differing from the experimentally infected opossums parasitism in the naturally infected animals predominated in the heart, esophagus and stomach. Parasitism of the scent glands did not affect the histopathological pattern observed in extraglandular tissues.

Study of the effect of electron irradiation on the density of the activated sludge in aqueous solution

NASA Astrophysics Data System (ADS)

Kupchishin, A. I.; Niyazov, M. N.; Taipova, B. G.; Voronova, N. A.; Khodarina, N. N.

2018-01-01

Complex experimental studies on the effect of electron irradiation on the deposition rate of active sludge in aqueous systems by the optical method have been carried out. The obtained dependences of density (ρ) on time (t) are of the same nature for different radiation sources. The experimental curves of the dependence of the active sludge density on time are satisfactorily described by an exponential model.

Comparative Packaging Study

NASA Technical Reports Server (NTRS)

Perchonok, Michele; Antonini, David

2008-01-01

This viewgraph presentation describes a comparative packaging study for use on long duration space missions. The topics include: 1) Purpose; 2) Deliverables; 3) Food Sample Selection; 4) Experimental Design Matrix; 5) Permeation Rate Comparison; and 6) Packaging Material Information.

Viscoelastic Response Of A Highly Filled Polymer

NASA Technical Reports Server (NTRS)

Peng, Steven T. J.; Landel, Robert F.

1992-01-01

Report describes experimental and theoretical studies of nonlinear viscoelastic response of elastomeric binder material filled with small particles of different material. Studies characterize response with sufficient accuracy for use in designing parts subjected to high strains.

Experimental approaches to well controlled studies of thin-film nucleation and growth.

NASA Technical Reports Server (NTRS)

Poppa, H.; Moorhead, R. D.; Heinemann, K.

1972-01-01

Particular features and the performance of two experimental systems are described for quantitative studies of thin-film nucleation and growth processes including epitaxial depositions. System I consists of a modified LEED-Auger instrument combined with high-resolution electron microscopy. System II is a UHV electron microscope adapted for in-situ deposition studies. The two systems complement each other ideally, and the combined use of both can result in a comprehensive investigation of vapor deposition processes not obtainable with any other known method.

Recent mouse and rat methods for the study of experimental oral candidiasis

PubMed Central

Costa, Anna CBP; Pereira, Cristiane A; Junqueira, Juliana C; Jorge, Antonio OC

2013-01-01

The Candida genus expresses virulence factors that, when combined with immunosuppression and other risk factors, can cause different manifestations of oral candidiasis. The treatment of mucosal infections caused by Candida and the elucidation of the disease process have proven challenging. Therefore, the study of experimentally induced oral candidiasis in rats and mice is useful to clarify the etiopathology of this condition, improve diagnosis, and search for new therapeutic options because the disease process in these animals is similar to that of human candidiasis lesions. Here, we describe and discuss new studies involving rat and mouse models of oral candidiasis with respect to methods for inducing experimental infection, methods for evaluating the development of experimental candidiasis, and new treatment strategies for oral candidiasis. PMID:23715031

The effect of dense gas dynamics on loss in ORC transonic turbines

NASA Astrophysics Data System (ADS)

Durá Galiana, FJ; Wheeler, APS; Ong, J.; Ventura, CA de M.

2017-03-01

This paper describes a number of recent investigations into the effect of dense gas dynamics on ORC transonic turbine performance. We describe a combination of experimental, analytical and computational studies which are used to determine how, in-particular, trailing-edge loss changes with choice of working fluid. A Ludwieg tube transient wind-tunnel is used to simulate a supersonic base flow which mimics an ORC turbine vane trailing-edge flow. Experimental measurements of wake profiles and trailing-edge base pressure with different working fluids are used to validate high-order CFD simulations. In order to capture the correct mixing in the base region, Large-Eddy Simulations (LES) are performed and verified against the experimental data by comparing the LES with different spatial and temporal resolutions. RANS and Detached-Eddy Simulation (DES) are also compared with experimental data. The effect of different modelling methods and working fluid on mixed-out loss is then determined. Current results point at LES predicting the closest agreement with experimental results, and dense gas effects are consistently predicted to increase loss.

Experimental Analysis of hFACT Action during Pol II Transcription in vitro

PubMed Central

Hsieh, Fu-Kai; Kulaeva, Olga I.; Studitsky, Vasily M.

2016-01-01

Summary FACT (facilitates chromatin transcription) is a histone chaperone that facilitates transcription through chromatin and promotes histone recovery during transcription. Here, we describe a highly purified experimental system that recapitulates many important properties of transcribed chromatin and the key aspects of hFACT action during this process in vitro. We present the protocols describing how to prepare different forms of nucleosomes, including intact nucleosome, covalently conjugated nucleosome, nucleosome missing one of the two H2A/2B dimers (hexasome) and tetrasome (a nucleosome missing both H2A/2B dimers). These complexes allow analysis of various aspects of FACT’s function. These approaches and other methods described below can also be applied to the study of other chromatin remodelers and chromatin-targeted factors. PMID:25665573

An experimental study of the putative mechanism of a synthetic autonomous rotary DNA nanomotor

NASA Astrophysics Data System (ADS)

Dunn, K. E.; Leake, M. C.; Wollman, A. J. M.; Trefzer, M. A.; Johnson, S.; Tyrrell, A. M.

2017-03-01

DNA has been used to construct a wide variety of nanoscale molecular devices. Inspiration for such synthetic molecular machines is frequently drawn from protein motors, which are naturally occurring and ubiquitous. However, despite the fact that rotary motors such as ATP synthase and the bacterial flagellar motor play extremely important roles in nature, very few rotary devices have been constructed using DNA. This paper describes an experimental study of the putative mechanism of a rotary DNA nanomotor, which is based on strand displacement, the phenomenon that powers many synthetic linear DNA motors. Unlike other examples of rotary DNA machines, the device described here is designed to be capable of autonomous operation after it is triggered. The experimental results are consistent with operation of the motor as expected, and future work on an enhanced motor design may allow rotation to be observed at the single-molecule level. The rotary motor concept presented here has potential applications in molecular processing, DNA computing, biosensing and photonics.

Teaching neurophysiology, neuropharmacology, and experimental design using animal models of psychiatric and neurological disorders.

PubMed

Morsink, Maarten C; Dukers, Danny F

2009-03-01

Animal models have been widely used for studying the physiology and pharmacology of psychiatric and neurological diseases. The concepts of face, construct, and predictive validity are used as indicators to estimate the extent to which the animal model mimics the disease. Currently, we used these three concepts to design a theoretical assignment to integrate the teaching of neurophysiology, neuropharmacology, and experimental design. For this purpose, seven case studies were developed in which animal models for several psychiatric and neurological diseases were described and in which neuroactive drugs used to treat or study these diseases were introduced. Groups of undergraduate students were assigned to one of these case studies and asked to give a classroom presentation in which 1) the disease and underlying pathophysiology are described, 2) face and construct validity of the animal model are discussed, and 3) a pharmacological experiment with the associated neuroactive drug to assess predictive validity is presented. After evaluation of the presentations, we found that the students had gained considerable insight into disease phenomenology, its underlying neurophysiology, and the mechanism of action of the neuroactive drug. Moreover, the assignment was very useful in the teaching of experimental design, allowing an in-depth discussion of experimental control groups and the prediction of outcomes in these groups if the animal model were to display predictive validity. Finally, the highly positive responses in the student evaluation forms indicated that the assignment was of great interest to the students. Hence, the currently developed case studies constitute a very useful tool for teaching neurophysiology, neuropharmacology, and experimental design.

Ayahuasca, dimethyltryptamine, and psychosis: a systematic review of human studies.

PubMed

Dos Santos, Rafael G; Bouso, José Carlos; Hallak, Jaime E C

2017-04-01

Ayahuasca is a hallucinogen brew traditionally used for ritual and therapeutic purposes in Northwestern Amazon. It is rich in the tryptamine hallucinogens dimethyltryptamine (DMT), which acts as a serotonin 5-HT 2A agonist. This mechanism of action is similar to other compounds such as lysergic acid diethylamide (LSD) and psilocybin. The controlled use of LSD and psilocybin in experimental settings is associated with a low incidence of psychotic episodes, and population studies corroborate these findings. Both the controlled use of DMT in experimental settings and the use of ayahuasca in experimental and ritual settings are not usually associated with psychotic episodes, but little is known regarding ayahuasca or DMT use outside these controlled contexts. Thus, we performed a systematic review of the published case reports describing psychotic episodes associated with ayahuasca and DMT intake. We found three case series and two case reports describing psychotic episodes associated with ayahuasca intake, and three case reports describing psychotic episodes associated with DMT. Several reports describe subjects with a personal and possibly a family history of psychosis (including schizophrenia, schizophreniform disorders, psychotic mania, psychotic depression), nonpsychotic mania, or concomitant use of other drugs. However, some cases also described psychotic episodes in subjects without these previous characteristics. Overall, the incidence of such episodes appears to be rare in both the ritual and the recreational/noncontrolled settings. Performance of a psychiatric screening before administration of these drugs, and other hallucinogens, in controlled settings seems to significantly reduce the possibility of adverse reactions with psychotic symptomatology. Individuals with a personal or family history of any psychotic illness or nonpsychotic mania should avoid hallucinogen intake.

Experimental Phasing: Substructure Solution and Density Modification as Implemented in SHELX.

PubMed

Thorn, Andrea

2017-01-01

This chapter describes experimental phasing methods as implemented in SHELX. After introducing fundamental concepts underlying all experimental phasing approaches, the methods used by SHELXC/D/E are described in greater detail, such as dual-space direct methods, Patterson seeding and density modification with the sphere of influence algorithm. Intensity differences from data for experimental phasing can also be used for the generation and usage of difference maps with ANODE for validation and phasing purposes. A short section describes how molecular replacement can be combined with experimental phasing methods. The second half covers practical challenges, such as prerequisites for successful experimental phasing, evaluation of potential solutions, and what to do if substructure search or density modification fails. It is also shown how auto-tracing in SHELXE can improve automation and how it ties in with automatic model building after phasing.

Atmosphere Behavior in Gas-Closed Mouse-Algal Systems: An Experimental and Modelling Study

NASA Technical Reports Server (NTRS)

Averner, M. M.; Moore, B., III; Bartholomew, I.; Wharton, R.

1985-01-01

A dual approach of mathematical modelling and laboratory experimentation aimed at examining the gas exchange characteristics of artificial animal/plant systems closed to the ambient atmosphere was initiated. The development of control techniques and management strategies for maintaining the atmospheric levels of carbon dioxide and oxygen at physiological levels is examined. A mathematical model simulating the atmospheric behavior in these systems was developed and an experimental gas closed system was constructed. These systems are described and preliminary results are presented.

Water-waves on linear shear currents. A comparison of experimental and numerical results.

NASA Astrophysics Data System (ADS)

Simon, Bruno; Seez, William; Touboul, Julien; Rey, Vincent; Abid, Malek; Kharif, Christian

2016-04-01

Propagation of water waves can be described for uniformly sheared current conditions. Indeed, some mathematical simplifications remain applicable in the study of waves whether there is no current or a linearly sheared current. However, the widespread use of mathematical wave theories including shear has rarely been backed by experimental studies of such flows. New experimental and numerical methods were both recently developed to study wave current interactions for constant vorticity. On one hand, the numerical code can simulate, in two dimensions, arbitrary non-linear waves. On the other hand, the experimental methods can be used to generate waves with various shear conditions. Taking advantage of the simplicity of the experimental protocol and versatility of the numerical code, comparisons between experimental and numerical data are discussed and compared with linear theory for validation of the methods. ACKNOWLEDGEMENTS The DGA (Direction Générale de l'Armement, France) is acknowledged for its financial support through the ANR grant N° ANR-13-ASTR-0007.

Experimental study of adaptive pointing and tracking for large flexible space structures

NASA Technical Reports Server (NTRS)

Boussalis, D.; Bayard, D. S.; Ih, C.; Wang, S. J.; Ahmed, A.

1991-01-01

This paper describes an experimental study of adaptive pointing and tracking control for flexible spacecraft conducted on a complex ground experiment facility. The algorithm used in this study is based on a multivariable direct model reference adaptive control law. Several experimental validation studies were performed earlier using this algorithm for vibration damping and robust regulation, with excellent results. The current work extends previous studies by addressing the pointing and tracking problem. As is consistent with an adaptive control framework, the plant is assumed to be poorly known to the extent that only system level knowledge of its dynamics is available. Explicit bounds on the steady-state pointing error are derived as functions of the adaptive controller design parameters. It is shown that good tracking performance can be achieved in an experimental setting by adjusting adaptive controller design weightings according to the guidelines indicated by the analytical expressions for the error.

Parameter determination of hereditary models of deformation of composite materials based on identification method

NASA Astrophysics Data System (ADS)

Kayumov, R. A.; Muhamedova, I. Z.; Tazyukov, B. F.; Shakirzjanov, F. R.

2018-03-01

In this paper, based on the analysis of some experimental data, a study and selection of hereditary models of deformation of reinforced polymeric composite materials, such as organic plastic, carbon plastic and a matrix of film-fabric composite, was pursued. On the basis of an analysis of a series of experiments it has been established that organo-plastic samples behave like viscoelastic bodies. It is shown that for sufficiently large load levels, the behavior of the material in question should be described by the relations of the nonlinear theory of heredity. An attempt to describe the process of deformation by means of linear relations of the theory of heredity leads to large discrepancies between the experimental and calculated deformation values. The use of the theory of accumulation of micro-damages leads to much better description of the experimental results. With the help of the hierarchical approach, a good approximation of the experimental values was successful only in the first three sections of loading.

A study of a rigid frame highway bridge in Virginia.

DOT National Transportation Integrated Search

1975-01-01

This report describes the experimental and analytical study of a rigid frame highway bridge conducted under the auspices of the Federal Highway Administration and the Virginia Highway & Transportation Research Council. Data collected during the exper...

The Challenge of Reproducibility and Accuracy in Nutrition Research: Resources and Pitfalls1234

PubMed Central

Kuszak, Adam J; Williamson, John S; Hopp, D Craig; Betz, Joseph M

2016-01-01

Inconsistent and contradictory results from nutrition studies conducted by different investigators continue to emerge, in part because of the inherent variability of natural products, as well as the unknown and therefore uncontrolled variables in study populations and experimental designs. Given these challenges inherent in nutrition research, it is critical for the progress of the field that researchers strive to minimize variability within studies and enhance comparability between studies by optimizing the characterization, control, and reporting of products, reagents, and model systems used, as well as the rigor and reporting of experimental designs, protocols, and data analysis. Here we describe some recent developments relevant to research on plant-derived products used in nutrition research, highlight some resources for optimizing the characterization and reporting of research using these products, and describe some of the pitfalls that may be avoided by adherence to these recommendations. PMID:26980822

Conceptual design study of Fusion Experimental Reactor (FY86 FER): Safety

NASA Astrophysics Data System (ADS)

Seki, Yasushi; Iida, Hiromasa; Honda, Tsutomu

1987-08-01

This report describes the study on safety for FER (Fusion Experimental Reactor) which has been designed as a next step machine to the JT-60. Though the final purpose of this study is to have an image of design base accident, maximum credible accident and to assess their risk or probability, etc., as FER plant system, the emphasis of this years study is placed on fuel-gas circulation system where the tritium inventory is maximum. The report consists of two chapters. The first chapter summarizes the FER system and describes FMEA (Failure Mode and Effect Analysis) and related accident progression sequence for FER plant system as a whole. The second chapter of this report is focused on fuel-gas circulation system including purification, isotope separation and storage. Probability of risk is assessed by the probabilistic risk analysis (PRA) procedure based on FMEA, ETA and FTA.

Identifying Effective Treatments from a Brief Experimental Analysis: Using a Single-Case Design Elements To Aid Decision Making.

ERIC Educational Resources Information Center

Martens, Brian K.; Eckert, Tanya L.; Bradley, Tracy A.; Ardoin, Scott P.

1999-01-01

Discusses the benefits of using brief experimental analysis to aid in treatment selection, identifies the forms of treatment that are most appropriate for this type of analysis, and describes key design elements for comparing treatments. Presents a study demonstrating the use of these design elements to identify an effective intervention for two…

Angle-Dependent Magnetoresistance in Organic Metals

NASA Astrophysics Data System (ADS)

Blundell, Stephen J.; Singleton, John

1996-12-01

Recent experimental studies of the angle-dependent magnetoresistance in various organic metals have been remarkably successful in elucidating the nature of the low-temperature ground state and providing information about the Fermi surface shape which is hard or impossible to obtain using other techniques. We review various theoretical approaches to describe angel-dependent magnetoresistance and a number of important experimental results which have been obtained.

A summary of special coatings projects conducted in support of the Die Casting Program

DOE Office of Scientific and Technical Information (OSTI.GOV)

Selle, J.E.

1988-09-12

The usefulness of various kinds of coatings to the die casting program has been studied. This work includes heat transfer and fluid flow calculations, as well as experimental work, to examine the feasibility and characteristics of various types of coatings. Calculations include the effect of surface roughness on fluid flow, conductance as a function of coating thickness, conductivity as a function of coating porosity, and solidification and possible remelting of microspheres of metal. In each case, the model is described and the results are presented. Experimental work involved evaluating the relative insulating value of various coatings and an analysis ofmore » commercial flame-sprayed coatings, low-density coatings, and release coatings. In each case, description of the experimental arrangement is given and the results are described. 5 refs., 28 figs., 6 tabs.« less

Magic Mirror, on the Wall-Which Is the Right Study Design of Them All?-Part I.

PubMed

Vetter, Thomas R

2017-06-01

The assessment of a new or existing treatment or intervention typically answers 1 of 3 research-related questions: (1) "Can it work?" (efficacy); (2) "Does it work?" (effectiveness); and (3) "Is it worth it?" (efficiency or cost-effectiveness). There are a number of study designs that on a situational basis are appropriate to apply in conducting research. These study designs are classified as experimental, quasi-experimental, or observational, with observational studies being further divided into descriptive and analytic categories. This first of a 2-part statistical tutorial reviews these 3 salient research questions and describes a subset of the most common types of experimental and quasi-experimental study design. Attention is focused on the strengths and weaknesses of each study design to assist in choosing which is appropriate for a given study objective and hypothesis as well as the particular study setting and available resources and data. Specific studies and papers are highlighted as examples of a well-chosen, clearly stated, and properly executed study design type.

Nonlinear dispersive waves in repulsive lattices

NASA Astrophysics Data System (ADS)

Mehrem, A.; Jiménez, N.; Salmerón-Contreras, L. J.; García-Andrés, X.; García-Raffi, L. M.; Picó, R.; Sánchez-Morcillo, V. J.

2017-07-01

The propagation of nonlinear waves in a lattice of repelling particles is studied theoretically and experimentally. A simple experimental setup is proposed, consisting of an array of coupled magnetic dipoles. By driving harmonically the lattice at one boundary, we excite propagating waves and demonstrate different regimes of mode conversion into higher harmonics, strongly influenced by dispersion and discreteness. The phenomenon of acoustic dilatation of the chain is also predicted and discussed. The results are compared with the theoretical predictions of the α -Fermi-Pasta-Ulam equation, describing a chain of masses connected by nonlinear quadratic springs and numerical simulations. The results can be extrapolated to other systems described by this equation.

Interface Pattern Selection Criterion for Cellular Structures in Directional Solidification

NASA Technical Reports Server (NTRS)

Trivedi, R.; Tewari, S. N.; Kurtze, D.

1999-01-01

The aim of this investigation is to establish key scientific concepts that govern the selection of cellular and dendritic patterns during the directional solidification of alloys. We shall first address scientific concepts that are crucial in the selection of interface patterns. Next, the results of ground-based experimental studies in the Al-4.0 wt % Cu system will be described. Both experimental studies and theoretical calculations will be presented to establish the need for microgravity experiments.

Bone as a secondary missile: an experimental study in the fragmenting of bone by high-velocity missiles.

PubMed

Amato, J J; Syracuse, D; Seaver, P R; Rich, N

1989-05-01

Destruction to soft tissues by bone fragments has been described in the literature. Civilian and military injuries have been reported in which bone fragments have acted as secondary missiles. This experimental study demonstrates, in detail, the formation of the temporary cavity within bone and the forward motion of these bone spicules. The knowledge of the ballistics will assist in the treatment of wounds caused by high-velocity missiles.

Acetylcholinesterase of the Sand Fly, Phlebotomus papatasi (Scopoli): Construction, Expression and Biochemical Properties of the G119S Orthologous Mutant

DTIC Science & Technology

2014-12-10

synthesis and agarose gel electrophoresis were as previously described [18]. Anticholinesterases as probes of enzyme function The experimental... anticholinesterases used in this study for enzyme characterization are shown in Figure 1. They were synthesized and purified via established methods [29-31] and had...structures and names of experimental anticholinesterases used in this study. Bold numbers beside the names denote the compounds as presented in the text. For

Long path-length experimental studies of longitudinal phenomena in intense beams

DOE Office of Scientific and Technical Information (OSTI.GOV)

Beaudoin, B. L.; Haber, I.; Kishek, R. A.

2016-05-15

Intense charged particle beams are nonneutral plasmas as they can support a host of plasma waves and instabilities. The longitudinal physics, for a long beam, can often be reasonably described by a 1-D cold-fluid model with a geometry factor to account for the transverse effects. The plasma physics of such beams has been extensively studied theoretically and computationally for decades, but until recently, the only experimental measurements were carried out on relatively short linacs. This work reviews experimental studies over the past five years on the University of Maryland Electron Ring, investigating longitudinal phenomena over time scales of thousands ofmore » plasma periods, illustrating good agreement with simulations.« less

Reliability-based structural optimization: A proposed analytical-experimental study

NASA Technical Reports Server (NTRS)

Stroud, W. Jefferson; Nikolaidis, Efstratios

1993-01-01

An analytical and experimental study for assessing the potential of reliability-based structural optimization is proposed and described. In the study, competing designs obtained by deterministic and reliability-based optimization are compared. The experimental portion of the study is practical because the structure selected is a modular, actively and passively controlled truss that consists of many identical members, and because the competing designs are compared in terms of their dynamic performance and are not destroyed if failure occurs. The analytical portion of this study is illustrated on a 10-bar truss example. In the illustrative example, it is shown that reliability-based optimization can yield a design that is superior to an alternative design obtained by deterministic optimization. These analytical results provide motivation for the proposed study, which is underway.

Experimental Criticality Benchmarks for SNAP 10A/2 Reactor Cores

DOE Office of Scientific and Technical Information (OSTI.GOV)

Krass, A.W.

2005-12-19

This report describes computational benchmark models for nuclear criticality derived from descriptions of the Systems for Nuclear Auxiliary Power (SNAP) Critical Assembly (SCA)-4B experimental criticality program conducted by Atomics International during the early 1960's. The selected experimental configurations consist of fueled SNAP 10A/2-type reactor cores subject to varied conditions of water immersion and reflection under experimental control to measure neutron multiplication. SNAP 10A/2-type reactor cores are compact volumes fueled and moderated with the hydride of highly enriched uranium-zirconium alloy. Specifications for the materials and geometry needed to describe a given experimental configuration for a model using MCNP5 are provided. Themore » material and geometry specifications are adequate to permit user development of input for alternative nuclear safety codes, such as KENO. A total of 73 distinct experimental configurations are described.« less

Parametric study of the 5d3, 5d2 6 s and 5d2 6 p configurations in the Lu I isoelectronic sequence (Ta III-Hg X) using orthogonal operators

NASA Astrophysics Data System (ADS)

Azarov, Vladimir I.

2018-01-01

Data available on the 5d3, 5d26s and 5d26p configurations in the Lu I isoelectronic sequence have been critically reviewed by means of calculations with the orthogonal operators. The study included spectra from Ta III through Hg X. The calculations agree very well with the experimental data. The isoelectronic behavior of parameters and deviations of the experimental levels from the calculated positions, ΔE = (Eexp -Ecalc), show regular trends. Three missing 5d26s levels have been accurately predicted theoretically and confirmed experimentally: the level (3P)2P3/2 in Pt VIII and the levels (3P)4P5/2 and (3P)2P1/2 in Os VI have been determined in the study. The research suggested revision of the published initial analyses of the Re V and Hg X spectra. The recently completed revised analysis of Re V has confirmed the issues noticed in the initial analysis and has resulted in the data that fit very well in the current parametric study. The isoelectronic evolution of the higher order interactions was studied for the first time in the Lu I sequence. The study included the parameters Ac, A3-A6 describing two-particle magnetic interaction of the dd-type, the parameter Amso describing two-particle magnetic ds-type effect, the parameter Tdds describing 3-particle electrostatic ds-type interaction, and the effective parameters S1 and S2 of the dp-type.

An experimental study of a turbulent boundary layer in the trailing edge region of a circulation-control airfoil

NASA Technical Reports Server (NTRS)

Heinemann, K.; Brown, Jeff

1992-01-01

This report discusses progress made on NASA Cooperative Agreement NCC2-545, 'An Experimental Study of a Turbulent Boundary Layer in the Trailing-Edge Region of a Circulation-Control Airfoil' during the period 9/1/91 through 9/30/92. The study features 2-component laser Doppler velocimeter (LDV) measurements in the trailing edge and wake regions of a generic 2-dimensional circulation-control model. The final experimental phase of the study will be carried out in the Ames High Reynolds Number Channel 2 (HRC2) transonic blow-down-facility. During the 13-month period covered by this report, work continued on the development of the near-wall laser Doppler velocimeter (LDV) described in previous reports.

Thermal Structures Technology Development for Reusable Launch Vehicle Cryogenic Propellant Tanks

NASA Technical Reports Server (NTRS)

Johnson, Theodore F.; Natividad, Roderick; Rivers, H. Kevin; Smith, Russell

1998-01-01

Analytical and experimental studies conducted at the NASA Langley Research Center for investigating integrated cryogenic propellant tank systems for a Reusable Launch Vehicle are described. The cryogenic tanks are investigated as an integrated tank system. An integrated tank system includes the tank wall, cryogenic insulation, Thermal Protection System (TPS) attachment sub-structure, and TPS. Analysis codes are used to size the thicknesses of cryogenic insulation and TPS insulation for thermal loads, and to predict tank buckling strengths at various ring frame spacings. The unique test facilities developed for the testing of cryogenic tank components are described. Testing at cryogenic and high-temperatures verifies the integrity of materials, design concepts, manufacturing processes, and thermal/structural analyses. Test specimens ranging from the element level to the subcomponent level are subjected to projected vehicle operational mechanical loads and temperatures. The analytical and experimental studies described in this paper provide a portion of the basic information required for the development of light-weight reusable cryogenic propellant tanks.

Thermal Structures Technology Development for Reusable Launch Vehicle Cryogenic Propellant Tanks

NASA Technical Reports Server (NTRS)

Johnson, Theodore F.; Natividad, Roderick; Rivers, H. Kevin; Smith, Russell W.

2005-01-01

Analytical and experimental studies conducted at the NASA, Langley Research Center (LaRC) for investigating integrated cryogenic propellant tank systems for a reusable launch vehicle (RLV) are described. The cryogenic tanks are investigated as an integrated tank system. An integrated tank system includes the tank wall, cryogenic insulation, thermal protection system (TPS) attachment sub-structure, and TPS. Analysis codes are used to size the thicknesses of cryogenic insulation and TPS insulation for thermal loads, and to predict tank buckling strengths at various ring frame spacings. The unique test facilities developed for the testing of cryogenic tank components are described. Testing at cryogenic and high-temperatures verifies the integrity of materials, design concepts, manufacturing processes, and thermal/structural analyses. Test specimens ranging from the element level to the subcomponent level are subjected to projected vehicle operational mechanical loads and temperatures. The analytical and experimental studies described in this paper provide a portion of the basic information required for the development of light-weight reusable cryogenic propellant tanks.

Forest management practices and silviculture. Chapter 12.

Treesearch

Donald A. Perala; Elon S. Verry

2011-01-01

This chapter is an overview of forest management and silviculture practices, and lessons learned, on the Marcell Experimental Forest (MEF). The forests there are a mosaic of natural regeneration and conifer plantations. Verry (1969) described forest-plant communities in detail for the study watersheds (Sl through S6) on the MEF. The remaining area is described in...

Arbitration Intervention Worker (AIW) Services: Case Management Overlay in a Juvenile Diversion Program

ERIC Educational Resources Information Center

Poythress, Norman G.; Dembo, Richard; DuDell, Gary; Wareham, Jennifer

2006-01-01

In this issue we describe a clinical trials study of the impact of adding specific case manager overlay services to "treatment as usual" services for youths in a Juvenile Arbitration Program. In this first article we describe the experimental intervention, the Arbitration Intervention Worker (AIW) service, which was provided to a randomly selected…

Light Learning.

ERIC Educational Resources Information Center

Cutshall, Sandy

2002-01-01

Describes a career and technical education program on photonics, the study, research, and development of equipment and concepts used in the transmission of information through light, including fiber optics and experimental laser technologies. (JOW)

Teaching Oscillations with a Small Computer.

ERIC Educational Resources Information Center

Calvo, J. L.; And Others

1983-01-01

Describes a simple, inexpensive electronic circuit used as a small analog computer in an experimental approach to the study of oscillations. Includes circuit diagram and an example of the method using steps followed by students studying underdamped oscillatory motion. (JN)

Research designs and making causal inferences from health care studies.

PubMed

Flannelly, Kevin J; Jankowski, Katherine R B

2014-01-01

This article summarizes the major types of research designs used in healthcare research, including experimental, quasi-experimental, and observational studies. Observational studies are divided into survey studies (descriptive and correlational studies), case-studies and analytic studies, the last of which are commonly used in epidemiology: case-control, retrospective cohort, and prospective cohort studies. Similarities and differences among the research designs are described and the relative strength of evidence they provide is discussed. Emphasis is placed on five criteria for drawing causal inferences that are derived from the writings of the philosopher John Stuart Mill, especially his methods or canons. The application of the criteria to experimentation is explained. Particular attention is given to the degree to which different designs meet the five criteria for making causal inferences. Examples of specific studies that have used various designs in chaplaincy research are provided.

Results of studying creep and long-term strength of metals at the Institute of Mechanics at the Lomonosov Moscow State University (To Yu. N. Rabotnov's Anniversary)

NASA Astrophysics Data System (ADS)

Lokoshchenko, A. M.

2014-01-01

Basic results of experimental and theoretical research of creep processes and long-term strength of metals obtained by researchers of the Institute of Mechanics at the Lomonosov Moscow State University are presented. These results further develop and refine the kinetic theory of creep and long-duration strength proposed by Yu. N. Rabotnov. Some problems arising in formulating various types of kinetic equations and describing experimental data for materials that can be considered as statically homogeneous materials (in studying the process of deformation and rupture of such materials, there is no need to study the evolution of individual cracks) are considered. The main specific features of metal creep models at constant and variable stresses, in uniaxial and complex stress states, and with allowance for one or two damage parameters are described. Criterial and kinetic approaches used to determine long-term strength under conditions of a complex stress state are considered. Methods of modeling the metal behavior in an aggressive medium are described. A possibility of using these models for solving engineering problems is demonstrated.

An experimental and theoretical study of structural damping in compliant foil bearings

NASA Technical Reports Server (NTRS)

Ku, C.-P. Roger

1994-01-01

This paper describes an experimental investigation into the dynamic characteristics of corrugated foil (bump foil) strips used in compliant surface foil bearings. This study provided and opportunity to quantify the structural damping of bump foil strips. The experimental data were compared to results obtained by a theoretical model developed earlier. The effects of bearing design parameters, such as static loads, dynamic displacement amplitudes, bump configurations, pivot locations, surface coatings, and lubricant were also evaluated. An understanding of the dynamic characteristics of bump foil strips resulting from this work offers designers a means for enhancing the design of high-performance compliant foil bearings.

STREAMS: From Learners to Leaders.

ERIC Educational Resources Information Center

Wilson, Frederic R.

1999-01-01

Describes a project for students to study storm water runoff, erosion, sedimentation, nutrient enrichment, wetlands, ground water, and the effects on waterways of acidity and household pollutants through experimentation and fieldwork. (CCM)

Comparative analysis of international standards for the fatigue testing of posterior spinal fixation systems: the importance of preload in ISO 12189.

PubMed

La Barbera, Luigi; Ottardi, Claudia; Villa, Tomaso

2015-10-01

Preclinical evaluation of the mechanical reliability of fixation devices is a mandatory activity before their introduction into market. There are two standardized protocols for preclinical testing of spinal implants. The American Society for Testing Materials (ASTM) recommends the F1717 standard, which describes a vertebrectomy condition that is relatively simple to implement, whereas the International Organization for Standardization (ISO) suggests the 12189 standard, which describes a more complex physiological anterior support-based setup. Moreover, ASTM F1717 is nowadays well established, whereas ISO 12189 has received little attention: A few studies tried to accurately describe the ISO experimental procedure through numeric models, but these studies totally neglect the recommended precompression step. This study aimed to build up a reliable, validated numeric model capable of describing the stress on the rods of a spinal fixator assembled according to ISO 12189 standard procedure. Such a model would more adequately represent the in vitro testing condition. This study used finite element (FE) simulations and experimental validation testing. An FE model of the ISO setup was built to calculate the stress on the rods. Simulation was validated by comparison with experimental strain gauges measurements. The same fixator has been previously virtually mounted in an L2-L4 FE model of the lumbar spine, and stresses in the rods were calculated when the spine was subjected to physiological forces and moments. The comparison between the FE predictions and experimental measurements is in good agreement, thus confirming the suitability of the FE method to evaluate the stresses in the device. The initial precompression induces a significant extension of the assembled construct. As the applied load increases, the initial extension is gradually compensated, so that at peak load the rods are bent in flexion: The final stress value predicted is thus reduced to about 50%, if compared with the previous model where the precompression was not considered. Neglecting the initial preload due to the assembly of the overall construct according to ISO 12189 standard could lead to an overestimation of the stress on the rods up to 50%. To correctly describe the state of stress on the posterior spinal fixator, tested according to the ISO procedure, it is important to take into account the initial preload due to the assembly of the overall construct. Copyright © 2015 Elsevier Inc. All rights reserved.

ANALYSIS OF METEOROLOGICAL CONDITIONS DURING THE 1977 ANCLOTE KEYS PLUME STUDY

EPA Science Inventory

Meteorological conditions are described and analyzed for nine experimental observation periods of the Anclote Keys Plume Study, which was conducted near Tampa, Florida during February 1977. The primary objective of the Plume Study was to investigate both the short and long range ...

A letter of intent for an experiment to study strong electromagnetic fields at RHIC via multiple electromagnetic processes

NASA Technical Reports Server (NTRS)

Fatyga, M.; Norbury, John W.

1992-01-01

An experimental program at the Relativistic Heavy Ion Collider (RHIC) which is designed to study nonperturbative aspects of electrodynamics is outlined. Additional possibilities for new studies of electrodynamics via multiple electromagnetic processes are also described.

Blood substitutes.

PubMed Central

Kostrzewska, E.

1976-01-01

With the development of modern methods of surgery, anaesthesia, and pre- and postoperative care the requirement for blood substitutes is continuously increasing. We present a review of the different blood substitutes which are already in clinical use or in an advanced stage of experimental investigation for possible practical administration. Our own clinical experience with dextrans and experimental studies on stroma-free haemoglobin and hydroxyethyl starch solutions are described. PMID:57736

Forward hadron calorimeter at MPD/NICA

NASA Astrophysics Data System (ADS)

Golubeva, M.; Guber, F.; Ivashkin, A.; Izvestnyy, A.; Kurepin, A.; Morozov, S.; Parfenov, P.; Petukhov, O.; Taranenko, A.; Selyuzhenkov, I.; Svintsov, I.

2017-01-01

Forward hadron calorimeter (FHCAL) at MPD/NICA experimental setup is described. The main purpose of the FHCAL is to provide an experimental measurement of a heavy-ion collision centrality (impact parameter) and orientation of its reaction plane. Precise event-by-event estimate of these basic observables is crucial for many physics phenomena studies to be performed by the MPD experiment. The simulation results of FHCAL performance are presented.

The Impact of Blended e-Learning on Undergraduate Academic Essay Writing in English (L2)

ERIC Educational Resources Information Center

Ferriman, Nicholas

2013-01-01

This paper describes a quasi-experimental study into the impact of a blended e-learning environment on academic writing assignments in English (L2) at a Thai international college. An experimental group of 15 students used an on-line bulletin board, as well as face-to-face (F2F) communication in class, to share information for essay topics they…

Development of Novel Models for Describing Multiple Toxicity Effects

DTIC Science & Technology

1994-10-12

Cimetidine and Thiopropazate Hydrochloride in the Prevention of Stress Ulcer Formation in Rats The Journal of Pharmacology and Experimental Therapeutics , 210...Synergism and Antagonism of GA and Growth Inhibitors on Growth and Sex Expression in Cucumber Journal of the American Society of Horticultural Science...for Synergism and Antagonism The Journal of Pharmacology and Experimental Therapeutics , 259, 1 286-294 (1991). compounds studied: APEC, CHA, NECA

Transplant rejection and tolerance – advancing the field through integration of computational and experimental investigation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Raimondi, Giorgio; Wood, Kathryn; Perelson, Alan S.

This Research Topic provides a venue for stimulating these interdisciplinary conversations in the context of transplantation. The articles collected under this Research Topic introduce new theoretical and experimental studies that describe novel techniques and methods for understanding the interactions between the immune response and transplants and for establishing more effective strategies of diagnosis and intervention that will promote transplant tolerance.

Project-based physics labs using low-cost open-source hardware

NASA Astrophysics Data System (ADS)

Bouquet, F.; Bobroff, J.; Fuchs-Gallezot, M.; Maurines, L.

2017-03-01

We describe a project-based physics lab, which we proposed to third-year university students. These labs are based on new open-source low-cost equipment (Arduino microcontrollers and compatible sensors). Students are given complete autonomy: they develop their own experimental setup and study the physics topic of their choice. The goal of these projects is to let students to discover the reality of experimental physics. Technical specifications of the acquisition material and case studies are presented for practical implementation in other universities.

Structural Qualification of Composite Airframes

NASA Technical Reports Server (NTRS)

Kedward, Keith T.; McCarty, John E.

1997-01-01

The development of fundamental approaches for predicting failure and elongation characteristics of fibrous composites are summarized in this document. The research described includes a statistical formulation for individual fiber breakage and fragmentation and clustered fiber breakage, termed macrodefects wherein the aligned composite may represent a structural component such as a reinforcing bar element, a rebar. Experimental work conducted in support of the future exploitation of aligned composite rebar elements is also described. This work discusses the experimental challenges associated with rebar tensile test evaluation and describes initial numerical analyses performed in support of the experimental program.

Experimental study of fs-laser induced sub-100-nm periodic surface structures on titanium.

PubMed

Nathala, Chandra S R; Ajami, Ali; Ionin, Andrey A; Kudryashov, Sergey I; Makarov, Sergey V; Ganz, Thomas; Assion, Andreas; Husinsky, Wolfgang

2015-03-09

In this work the formation of laser-induced periodic surface structures (LIPSS) on a titanium surface upon irradiation by linearly polarized femtosecond (fs) laser pulses with a repetition rate of 1 kHz in air environment was studied experimentally. In particular, the dependence of high-spatial-frequency-LIPSS (HSFL) characteristics on various laser parameters: fluence, pulse number, wavelength (800 nm and 400 nm), pulse duration (10 fs - 550 fs), and polarization was studied in detail. In comparison with low-spatial-frequency-LIPSS (LSFL), the HSFL emerge at a much lower fluence with orientation perpendicular to the ridges of the LSFL. It was observed that these two types of LIPSS demonstrate different fluence, shot number and wavelength dependencies, which suggest their origin is different. Therefore, the HSFL formation mechanism cannot be described by the widely accepted interference model developed for describing LSFL formation.

Ayahuasca, dimethyltryptamine, and psychosis: a systematic review of human studies

PubMed Central

dos Santos, Rafael G.; Bouso, José Carlos; Hallak, Jaime E. C.

2017-01-01

Ayahuasca is a hallucinogen brew traditionally used for ritual and therapeutic purposes in Northwestern Amazon. It is rich in the tryptamine hallucinogens dimethyltryptamine (DMT), which acts as a serotonin 5-HT2A agonist. This mechanism of action is similar to other compounds such as lysergic acid diethylamide (LSD) and psilocybin. The controlled use of LSD and psilocybin in experimental settings is associated with a low incidence of psychotic episodes, and population studies corroborate these findings. Both the controlled use of DMT in experimental settings and the use of ayahuasca in experimental and ritual settings are not usually associated with psychotic episodes, but little is known regarding ayahuasca or DMT use outside these controlled contexts. Thus, we performed a systematic review of the published case reports describing psychotic episodes associated with ayahuasca and DMT intake. We found three case series and two case reports describing psychotic episodes associated with ayahuasca intake, and three case reports describing psychotic episodes associated with DMT. Several reports describe subjects with a personal and possibly a family history of psychosis (including schizophrenia, schizophreniform disorders, psychotic mania, psychotic depression), nonpsychotic mania, or concomitant use of other drugs. However, some cases also described psychotic episodes in subjects without these previous characteristics. Overall, the incidence of such episodes appears to be rare in both the ritual and the recreational/noncontrolled settings. Performance of a psychiatric screening before administration of these drugs, and other hallucinogens, in controlled settings seems to significantly reduce the possibility of adverse reactions with psychotic symptomatology. Individuals with a personal or family history of any psychotic illness or nonpsychotic mania should avoid hallucinogen intake. PMID:28540034

Structural Acoustic Response of a Shape Memory Alloy Hybrid Composite Panel (Lessons Learned)

NASA Technical Reports Server (NTRS)

Turner, Travis L.

2002-01-01

This study presents results from an effort to fabricate a shape memory alloy hybrid composite (SMAHC) panel specimen and test the structure for dynamic response and noise transmission characteristics under the action of thermal and random acoustic loads. A method for fabricating a SMAHC laminate with bi-directional SMA reinforcement is described. Glass-epoxy unidirectional prepreg tape and Nitinol ribbon comprise the material system. Thermal activation of the Nitinol actuators was achieved through resistive heating. The experimental hardware required for mechanical support of the panel/actuators and for establishing convenient electrical connectivity to the actuators is presented. Other experimental apparatus necessary for controlling the panel temperature and acquiring structural acoustic data are also described. Deficiency in the thermal control system was discovered in the process of performing the elevated temperature tests. Discussion of the experimental results focuses on determining the causes for the deficiency and establishing means for rectifying the problem.

Structural acoustic response of a shape memory alloy hybrid composite panel (lessons learned)

NASA Astrophysics Data System (ADS)

Turner, Travis L.

2002-07-01

This study presents results from an effort to fabricate a shape memory alloy hybrid composite (SMAHC) panel specimen and test the structure for dynamic response and noise transmission characteristics under the action of thermal and random acoustic loads. A method for fabricating a SMAHC laminate with bi-directional SMA reinforcement is described. Glass-epoxy unidirectional prepreg tape and Nitinol ribbon comprise the material system. Thermal activation of the Nitinol actuators was achieved through resistive heating. The experimental hardware required for mechanical support of the panel/actuators and for establishing convenient electrical connectivity to the actuators is presented. Other experimental apparatus necessary for controlling the panel temperature and acquiring structural acoustic data are also described. Deficiency in the thermal control system was discovered in the process of performing the elevated temperature tests. Discussion of the experimental results focuses on determining the causes for the deficiency and establishing means for rectifying the problem.

Comparison Between Numerically Simulated and Experimentally Measured Flowfield Quantities Behind a Pulsejet

NASA Technical Reports Server (NTRS)

Geng, Tao; Paxson, Daniel E.; Zheng, Fei; Kuznetsov, Andrey V.; Roberts, William L.

2008-01-01

Pulsed combustion is receiving renewed interest as a potential route to higher performance in air breathing propulsion systems. Pulsejets offer a simple experimental device with which to study unsteady combustion phenomena and validate simulations. Previous computational fluid dynamic (CFD) simulation work focused primarily on the pulsejet combustion and exhaust processes. This paper describes a new inlet sub-model which simulates the fluidic and mechanical operation of a valved pulsejet head. The governing equations for this sub-model are described. Sub-model validation is provided through comparisons of simulated and experimentally measured reed valve motion, and time averaged inlet mass flow rate. The updated pulsejet simulation, with the inlet sub-model implemented, is validated through comparison with experimentally measured combustion chamber pressure, inlet mass flow rate, operational frequency, and thrust. Additionally, the simulated pulsejet exhaust flowfield, which is dominated by a starting vortex ring, is compared with particle imaging velocimetry (PIV) measurements on the bases of velocity, vorticity, and vortex location. The results show good agreement between simulated and experimental data. The inlet sub-model is shown to be critical for the successful modeling of pulsejet operation. This sub-model correctly predicts both the inlet mass flow rate and its phase relationship with the combustion chamber pressure. As a result, the predicted pulsejet thrust agrees very well with experimental data.

Experimental observation of Lorenz chaos in the Quincke rotor dynamics.

PubMed

Peters, François; Lobry, Laurent; Lemaire, Elisabeth

2005-03-01

In this paper, we report experimental evidence of Lorenz chaos for the Quincke rotor dynamics. We study the angular motion of an insulating cylinder immersed in slightly conducting oil and submitted to a direct current electric field. The simple equations which describe the dynamics of the rotor are shown to be equivalent to the Lorenz equations. In particular, we observe two bifurcations in our experimental system. Above a critical value of the electric field, the cylinder rotates at a constant rate. At a second bifurcation, the system becomes chaotic. The characteristic shape of the experimental first return map provides strong evidence for Lorenz-type chaos.

Experimental observation of Lorenz chaos in the Quincke rotor dynamics

NASA Astrophysics Data System (ADS)

Peters, François; Lobry, Laurent; Lemaire, Elisabeth

2005-03-01

In this paper, we report experimental evidence of Lorenz chaos for the Quincke rotor dynamics. We study the angular motion of an insulating cylinder immersed in slightly conducting oil and submitted to a direct current electric field. The simple equations which describe the dynamics of the rotor are shown to be equivalent to the Lorenz equations. In particular, we observe two bifurcations in our experimental system. Above a critical value of the electric field, the cylinder rotates at a constant rate. At a second bifurcation, the system becomes chaotic. The characteristic shape of the experimental first return map provides strong evidence for Lorenz-type chaos.

Developments in the field of allergy mechanisms in 2015 through the eyes of Clinical & Experimental Allergy.

PubMed

Roberts, G; Boyle, R; Bryce, P J; Crane, J; Hogan, S P; Saglani, S; Wickman, M; Woodfolk, J A

2016-10-01

In the first of two papers we described the development in the field of allergy mechanisms as described by Clinical and Experimental Allergy in 2015. Experimental models of allergic disease, basic mechanisms, clinical mechanisms and allergens are all covered. A second paper will cover clinical aspects. © 2016 John Wiley & Sons Ltd.

Skin-stringer panel normal mode response experimental data and finite element computer program documentation

NASA Technical Reports Server (NTRS)

Rudder, F. F., Jr.

1971-01-01

Detailed information is presented for the analytical and the experimental programs described in the report on Effects of Design Details on Structural Response to Acoustic Excitation, NASA CR-1959. This is a supplement to the basic report and detailed experimental data from all the specimens described in that report are discussed and presented in tabular form.

Experimental investigation of the dynamics of a brake shoe

NASA Astrophysics Data System (ADS)

Ivanova, T. B.; Erdakova, N. N.; Karavaev, Yu. L.

2016-12-01

The experimental stand is described and the results of investigation of the motion of a brake shoe are presented. In the noncritical region, the friction coefficient is determined experimentally. It is shown that its value corresponds to the condition of uniqueness of the solution for construction of this brake shoe. The dynamics observed in the paradoxical-motion region is described.

A non-linear regression analysis program for describing electrophysiological data with multiple functions using Microsoft Excel.

PubMed

Brown, Angus M

2006-04-01

The objective of this present study was to demonstrate a method for fitting complex electrophysiological data with multiple functions using the SOLVER add-in of the ubiquitous spreadsheet Microsoft Excel. SOLVER minimizes the difference between the sum of the squares of the data to be fit and the function(s) describing the data using an iterative generalized reduced gradient method. While it is a straightforward procedure to fit data with linear functions, and we have previously demonstrated a method of non-linear regression analysis of experimental data based upon a single function, it is more complex to fit data with multiple functions, usually requiring specialized expensive computer software. In this paper we describe an easily understood program for fitting experimentally acquired data, in this case the stimulus-evoked compound action potential from the mouse optic nerve, with multiple Gaussian functions. The program is flexible and can be applied to describe data with a wide variety of user-input functions.

Experimental studies of two-stage centrifugal dust concentrator

NASA Astrophysics Data System (ADS)

Vechkanova, M. V.; Fadin, Yu M.; Ovsyannikov, Yu G.

2018-03-01

The article presents data of experimental results of two-stage centrifugal dust concentrator, describes its design, and shows the development of a method of engineering calculation and laboratory investigations. For the experiments, the authors used quartz, ceramic dust and slag. Experimental dispersion analysis of dust particles was obtained by sedimentation method. To build a mathematical model of the process, dust collection was built using central composite rotatable design of the four factorial experiment. A sequence of experiments was conducted in accordance with the table of random numbers. Conclusion were made.

Ethical review of human experimentation in the consumer products industry.

PubMed

Steadman, J H

1998-04-01

Ethical review of human experimentation in the consumer products industry is important and provides instructive parallels and contrasts with clinical medical research. The procedures used in Unilever NV/plc are described. A central body sets standards for and monitors compliance with ethical review of human studies throughout Unilever. Guidance has been produced on many topics including issues applying generally to human experimentation and more specifically to the consumer products sector. Deficiencies and inconsistencies in the procedures for ethical review and the care of subjects during the conduct of studies have been identified and corrected. Appropriate uniform standards have been achieved across all Unilever operations. All human experimentation in the industry needs adequate ethical review. Although the methods used by individual companies may differ, procedures must ensure uniform high standards across a global industry.

Experimental software engineering: Seventeen years of lessons in the SEL

NASA Technical Reports Server (NTRS)

Mcgarry, Frank E.

1992-01-01

Seven key principles developed by the Software Engineering Laboratory (SEL) at the Goddard Space Flight Center (GSFC) of the National Aeronautics and Space Administration (NASA) are described. For the past 17 years, the SEL has been experimentally analyzing the development of production software as varying techniques and methodologies are applied in this one environment. The SEL has collected, archived, and studied detailed measures from more than 100 flight dynamics projects, thereby gaining significant insight into the effectiveness of numerous software techniques, as well as extensive experience in the overall effectiveness of 'Experimental Software Engineering'. This experience has helped formulate follow-on studies in the SEL, and it has helped other software organizations better understand just what can be accomplished and what cannot be accomplished through experimentation.

Project EX: A Program of Empirical Research on Adolescent Tobacco Use Cessation

PubMed Central

Sussman, Steve; McCuller, William J; Zheng, Hong; Pfingston, Yvonne M; Miyano, James; Dent, Clyde W

2004-01-01

This paper presents the Project EX research program. The historical background for Project EX is presented, including a brief summary of reasons youth fail to quit tobacco use, the disappointing status of previous cessation research, and the teen cessation trial that provided the template for the current project (Project TNT). Next, program development studies for Project EX are described. Through use of focus groups, a theme study (concept evaluation of written activity descriptions), a component study, and pilot studies, an eight-session program was developed. This program involves novel activities (e.g., "talk show enactments," games, and alternative medicine-type activities such as yoga and meditation) in combination with motivation enhancement and cognitive-behavioral strategies to motivate and instruct in cessation initiation and maintenance efforts. The outcomes of the first experimental trial of Project EX, a school-based clinic program, are described, followed by a posthoc analysis of its effects mediation. A second EX study, a multiple baseline single group pilot study design in Wuhan, China, is described next. Description of a second experimental trial follows, which tested EX with nicotine gum versus a natural herb. A third experimental trial that tests a classroom prevention/cessation version of EX is then introduced. Finally, the implications of this work are discussed. The intent-to-treat quit rate for Project EX is approximately 15% across studies, double that of a standard care comparison. Effects last up to a six-month post-program at regular and alternative high schools. Through a systematic protocol of empirical program development and field trials, an effective and replicable model teen tobacco use cessation program is established. Future cessation work might expand on this work.

Project EX: A Program of Empirical Research on Adolescent Tobacco Use Cessation

PubMed Central

Sussman, Steve; McCuller, William J; Zheng, Hong; Pfingston, Yvonne M; Miyano, James; Dent, Clyde W

2004-01-01

This paper presents the Project EX research program. The historical background for Project EX is presented, including a brief summary of reasons youth fail to quit tobacco use, the disappointing status of previous cessation research, and the teen cessation trial that provided the template for the current project (Project TNT). Next, program development studies for Project EX are described. Through use of focus groups, a theme study (concept evaluation of written activity descriptions), a component study, and pilot studies, an eight-session program was developed. This program involves novel activities (e.g., "talk show enactments," games, and alternative medicine-type activities such as yoga and meditation) in combination with motivation enhancement and cognitive-behavioral strategies to motivate and instruct in cessation initiation and maintenance efforts. The outcomes of the first experimental trial of Project EX, a school-based clinic program, are described, followed by a posthoc analysis of its effects mediation. A second EX study, a multiple baseline single group pilot study design in Wuhan, China, is described next. Description of a second experimental trial follows, which tested EX with nicotine gum versus a natural herb. A third experimental trial that tests a classroom prevention/cessation version of EX is then introduced. Finally, the implications of this work are discussed. The intent-to-treat quit rate for Project EX is approximately 15% across studies, double that of a standard care comparison. Effects last up to a six-month post-program at regular and alternative high schools. Through a systematic protocol of empirical program development and field trials, an effective and replicable model teen tobacco use cessation program is established. Future cessation work might expand on this work. PMID:19570278

Experimental study and simulation of space charge stimulated discharge

NASA Astrophysics Data System (ADS)

Noskov, M. D.; Malinovski, A. S.; Cooke, C. M.; Wright, K. A.; Schwab, A. J.

2002-11-01

The electrical discharge of volume distributed space charge in poly(methylmethacrylate) (PMMA) has been investigated both experimentally and by computer simulation. The experimental space charge was implanted in dielectric samples by exposure to a monoenergetic electron beam of 3 MeV. Electrical breakdown through the implanted space charge region within the sample was initiated by a local electric field enhancement applied to the sample surface. A stochastic-deterministic dynamic model for electrical discharge was developed and used in a computer simulation of these breakdowns. The model employs stochastic rules to describe the physical growth of the discharge channels, and deterministic laws to describe the electric field, the charge, and energy dynamics within the discharge channels and the dielectric. Simulated spatial-temporal and current characteristics of the expanding discharge structure during physical growth are quantitatively compared with the experimental data to confirm the discharge model. It was found that a single fixed set of physically based dielectric parameter values was adequate to simulate the complete family of experimental space charge discharges in PMMA. It is proposed that such a set of parameters also provides a useful means to quantify the breakdown properties of other dielectrics.

Experimental Study of Damage Evolution in Circular Stirrup-Confined Concrete

PubMed Central

Li, Zuohua; Peng, Zhihan; Teng, Jun; Wang, Ying

2016-01-01

This paper presents an experimental study on circular stirrup-confined concrete specimens under uniaxial and monotonic load. The effects of stirrup volume ratio, stirrup yield strength and concrete strength on damage evolution of stirrup-confined concrete were investigated. The experimental results showed that the strength and ductility of concrete are improved by appropriate arrangement of the stirrup confinement. Firstly, the concrete damage evolution can be relatively restrained with the increase of the stirrup volume ratio. Secondly, higher stirrup yield strength usually causes larger confining pressures and slower concrete damage evolution. In contrast, higher concrete strength leads to higher brittleness, which accelerates the concrete damage evolution. A plastic strain expression is obtained through curve fitting, and a damage evolution equation for circular stirrup-confined concrete is proposed by introducing a confinement factor (C) based on the experimental data. The comparison results demonstrate that the proposed damage evolution model can accurately describe the experimental results. PMID:28773402

Experimental Study of Damage Evolution in Circular Stirrup-Confined Concrete.

PubMed

Li, Zuohua; Peng, Zhihan; Teng, Jun; Wang, Ying

2016-04-08

This paper presents an experimental study on circular stirrup-confined concrete specimens under uniaxial and monotonic load. The effects of stirrup volume ratio, stirrup yield strength and concrete strength on damage evolution of stirrup-confined concrete were investigated. The experimental results showed that the strength and ductility of concrete are improved by appropriate arrangement of the stirrup confinement. Firstly, the concrete damage evolution can be relatively restrained with the increase of the stirrup volume ratio. Secondly, higher stirrup yield strength usually causes larger confining pressures and slower concrete damage evolution. In contrast, higher concrete strength leads to higher brittleness, which accelerates the concrete damage evolution. A plastic strain expression is obtained through curve fitting, and a damage evolution equation for circular stirrup-confined concrete is proposed by introducing a confinement factor ( C ) based on the experimental data. The comparison results demonstrate that the proposed damage evolution model can accurately describe the experimental results.

Human Judgment and the Logic of Evidence: A Critical Examination of Research Methods in Special Education Transition Literature.

ERIC Educational Resources Information Center

Harnisch, Delwyn L.; And Others

This paper describes several common types of research studies in special education transition literature and the threats to their validity. It then describes how the evidential base may be broadened, how diverse sources of evidence can be combined to strengthen causal inferences, and the role of judgment within quasi-experimentation. The paper…

Assessment of Cable Aging Equipment, Status of Acquired Materials, and Experimental Matrix at the Pacific Northwest National Laboratory

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fifield, Leonard S.; Westman, Matthew P.; Zwoster, Andy

2015-03-30

The need for increased understanding of the aging and degradation behavior for polymer components of nuclear power plant electrical cables is described in this report. The highest priority materials for study and the resources available at PNNL for these studies are also described. The anticipated outcomes of the PNNL work described are : improved understanding of appropriate accelerated aging conditions, improved knowledge of correlation between observable aging indicators and cable condition in support of advanced non-destructive evaluation methods, and practical knowledge of condition-based cable lifetime prediction.

Experiments With Magnetic Vector Potential

ERIC Educational Resources Information Center

Skinner, J. W.

1975-01-01

Describes the experimental apparatus and method for the study of magnetic vector potential (MVP). Includes a discussion of inherent errors in the calculations involved, precision of the results, and further applications of MVP. (GS)

The Perspective Structure of Visual Space

PubMed Central

2015-01-01

Luneburg’s model has been the reference for experimental studies of visual space for almost seventy years. His claim for a curved visual space has been a source of inspiration for visual scientists as well as philosophers. The conclusion of many experimental studies has been that Luneburg’s model does not describe visual space in various tasks and conditions. Remarkably, no alternative model has been suggested. The current study explores perspective transformations of Euclidean space as a model for visual space. Computations show that the geometry of perspective spaces is considerably different from that of Euclidean space. Collinearity but not parallelism is preserved in perspective space and angles are not invariant under translation and rotation. Similar relationships have shown to be properties of visual space. Alley experiments performed early in the nineteenth century have been instrumental in hypothesizing curved visual spaces. Alleys were computed in perspective space and compared with reconstructed alleys of Blumenfeld. Parallel alleys were accurately described by perspective geometry. Accurate distance alleys were derived from parallel alleys by adjusting the interstimulus distances according to the size-distance invariance hypothesis. Agreement between computed and experimental alleys and accommodation of experimental results that rejected Luneburg’s model show that perspective space is an appropriate model for how we perceive orientations and angles. The model is also appropriate for perceived distance ratios between stimuli but fails to predict perceived distances. PMID:27648222

The Nematode Caenorhabditis Elegans.

ERIC Educational Resources Information Center

Kenyon, Cynthia

1988-01-01

Discusses advantages of nematode use for studying patterns of cell division, differentiation, and morphogenesis. Describes nematode development. Cites experimental approaches available for genetic studies. Reviews the topics of control of cell division and differentiation, the nervous system, and muscle assembly and function of the organism. (RT)

An experiment in multispectral, multitemporal crop classification using relaxation techniques

NASA Technical Reports Server (NTRS)

Davis, L. S.; Wang, C.-Y.; Xie, H.-C

1983-01-01

The paper describes the result of an experimental study concerning the use of probabilistic relaxation for improving pixel classification rates. Two LACIE sites were used in the study and in both cases, relaxation resulted in a marked improvement in classification rates.

47 CFR 5.309 - Notification requirements.

Code of Federal Regulations, 2013 CFR

2013-10-01

... experiment, program experimental licensees must provide the following information to the Commission's program experimental registration Web site. (1) A narrative statement describing the experiment, including a... licensee; (2) Contact information for the researcher-in-charge of the described experiment; (3) Contact...

47 CFR 5.309 - Notification requirements.

Code of Federal Regulations, 2014 CFR

2014-10-01

... experiment, program experimental licensees must provide the following information to the Commission's program experimental registration Web site. (1) A narrative statement describing the experiment, including a... licensee; (2) Contact information for the researcher-in-charge of the described experiment; (3) Contact...

Space charge effects on the third order coupled resonance

NASA Astrophysics Data System (ADS)

Franchetti, Giuliano; Gilardoni, Simone; Huschauer, Alexander; Schmidt, Frank; Wasef, Raymond

2017-08-01

The effect of space charge on bunched beams has been the subject of numerous numerical and experimental studies in the first decade of 2000. Experimental campaigns performed at the CERN Proton Synchrotron in 2002 and at the GSI SIS18 in 2008 confirmed the existence of an underlying mechanism in the beam dynamics of periodic resonance crossing induced by the synchrotron motion and space charge. In this article we present an extension of the previous studies to describe the effect of space charge on a controlled coupled (2D) third order resonance. The experimental and simulation results of this latest campaign shed a new light on the difficulties of the 2D particle dynamics. We find striking experimental evidence that space charge and the coupled resonance create an unusual coupling in the phase space, leading to the formation of an asymmetric halo. Moreover, this study demonstrates a clear link between halo formation and fixed-lines.

Coherence Measurements for Excited to Excited State Transitions in Barium

NASA Technical Reports Server (NTRS)

Trajmar, S.; Kanik, I.; Karaganov, V.; Zetner, P. W.; Csanak, G.

2000-01-01

Experimental studies concerning elastic and inelastic electron scattering by coherently ensembles of Ba (...6s6p (sub 1)P(sub 1)) atoms with various degrees of alignment will be described. An in-plane, linearly-polarized laser beam was utilized to prepare these target ensembles and the electron scattering signal as a function of polarization angle was measured for several laser geometries at fixed impact energies and scattering angles. From these measurements, we derived cross sections and electron-impact coherence parameters associated with the electron scattering process which is time reverse of the actual experimentally studied process. This interpretation of the experiment is based on the theory of Macek and Herte. The experimental results were also interpreted in terms of cross sections and collision parameters associated with the actual experimental processes. Results obtained so far will be presented and plans for further studies will be discussed.

Analytical and experimental study of the acoustics and the flow field characteristics of cavitating self-resonating water jets

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chahine, G.L.; Genoux, P.F.; Johnson, V.E. Jr.

1984-09-01

Waterjet nozzles (STRATOJETS) have been developed which achieve passive structuring of cavitating submerged jets into discrete ring vortices, and which possess cavitation incipient numbers six times higher than obtained with conventional cavitating jet nozzles. In this study we developed analytical and numerical techniques and conducted experimental work to gain an understanding of the basic phenomena involved. The achievements are: (1) a thorough analysis of the acoustic dynamics of the feed pipe to the nozzle; (2) a theory for bubble ring growth and collapse; (3) a numerical model for jet simulation; (4) an experimental observation and analysis of candidate second-generation low-sigmamore » STRATOJETS. From this study we can conclude that intensification of bubble ring collapse and design of highly resonant feed tubes can lead to improved drilling rates. The models here described are excellent tools to analyze the various parameters needed for STRATOJET optimizations. Further analysis is needed to introduce such important factors as viscosity, nozzle-jet interaction, and ring-target interaction, and to develop the jet simulation model to describe the important fine details of the flow field at the nozzle exit.« less

Analysis of Spacelab-III Reconstructed Wavefronts by Non-Holographic Methods

NASA Technical Reports Server (NTRS)

Vikram, Chandra S.; Witherow, William K.; Rose, M. Franklin (Technical Monitor)

2001-01-01

Holography has been used in several past space missions. One popular experimental mode deals with study of fluid refractive properties in the crystal growth cell. The perceived advantage of holography is that it stores and reconstructs wavefronts so that a complete information is available later on ground. That means the wavefront can be analyzed not only by traditional holographic interferometry but other means as well. We have successfully demonstrated two such means being described here. One is deflectometry using a Ronchi grating and the other confocal optical processing. These results, using holograms from Spacelab-III mission dealing with triglycine sulfate crystal growth clearly demonstrate that a single hardware (holography) can do the task of several fluid experimental systems. Finally, not experimentally demonstrated, the possibility of some other analysis modes like speckle techniques and video holography using the reconstructed wavefronts have been described. Since only traditional holographic interferometry has been used in the past leading to the argument that non-holographic interferometry hardware in space could do the job, the present study firmly establishes advantage of holography.

Experimental and Imaging Techniques for Examining Fibrin Clot Structures in Normal and Diseased States

PubMed Central

Fan, Natalie K.; Keegan, Philip M.; Platt, Manu O.; Averett, Rodney D.

2015-01-01

Fibrin is an extracellular matrix protein that is responsible for maintaining the structural integrity of blood clots. Much research has been done on fibrin in the past years to include the investigation of synthesis, structure-function, and lysis of clots. However, there is still much unknown about the morphological and structural features of clots that ensue from patients with disease. In this research study, experimental techniques are presented that allow for the examination of morphological differences of abnormal clot structures due to diseased states such as diabetes and sickle cell anemia. Our study focuses on the preparation and evaluation of fibrin clots in order to assess morphological differences using various experimental assays and confocal microscopy. In addition, a method is also described that allows for continuous, real-time calculation of lysis rates in fibrin clots. The techniques described herein are important for researchers and clinicians seeking to elucidate comorbid thrombotic pathologies such as myocardial infarctions, ischemic heart disease, and strokes in patients with diabetes or sickle cell disease. PMID:25867016

A novel open-source drug-delivery system that allows for first-of-kind simulation of nonadherence to pharmacological interventions in animal disease models.

PubMed

Thomson, Kyle E; White, H Steve

2014-12-30

Nonadherence to a physician-prescribed therapeutic intervention is a costly, dangerous, and sometimes fatal concern in healthcare. To date, the study of nonadherence has been constrained to clinical studies. The novel approach described herein allows for the preclinical study of nonadherence in etiologically relevant disease animal model systems. The method herein describes a novel computer-automated pellet delivery system which allows for the study of nonadherence in animals. This system described herein allows for tight experimenter control of treatment using a drug-in-food protocol. Food-restricted animals receive either medicated or unmedicated pellets, designed to mimic either "taking" or "missing" a drug. The system described permits the distribution of medicated or unmedicated food pellets on an experimenter-defined feeding schedule. The flexibility of this system permits the delivery of drug according to the known pharmacokinetics of investigational drugs. Current clinical adherence research relies on medication-event monitoring system (MEMS) tracking caps, which allows clinicians to directly monitor patient adherence. However, correlating the effects of nonadherence to efficacy still relies on the accuracy of patient journals. This system allows for the design of studies to address the impact of nonadherence in an etiologically relevant animal model. Given methodological and ethical concerns of designing clinical studies of nonadherence, animal studies are critical to better understand medication adherence. While the system described was designed to measure the impact of nonadherence on seizure control, it is clear that the utility of this system extends beyond epilepsy to include other disease states. Copyright © 2014 Elsevier B.V. All rights reserved.

CXSFIT Code Application to Process Charge-Exchange Recombination Spectroscopy Data at the T-10 Tokamak

NASA Astrophysics Data System (ADS)

Serov, S. V.; Tugarinov, S. N.; Klyuchnikov, L. A.; Krupin, V. A.; von Hellermann, M.

2017-12-01

The applicability of the CXSFIT code to process experimental data from Charge-eXchange Recombination Spectroscopy (CXRS) diagnostics at the T-10 tokamak is studied with a view to its further use for processing experimental data at the ITER facility. The design and operating principle of the CXRS diagnostics are described. The main methods for processing the CXRS spectra of the 5291-Å line of C5+ ions at the T-10 tokamak (with and without subtraction of parasitic emission from the edge plasma) are analyzed. The method of averaging the CXRS spectra over several shots, which is used at the T-10 tokamak to increase the signal-to-noise ratio, is described. The approximation of the spectrum by a set of Gaussian components is used to identify the active CXRS line in the measured spectrum. Using the CXSFIT code, the ion temperature in ohmic discharges and discharges with auxiliary electron cyclotron resonance heating (ECRH) at the T-10 tokamak is calculated from the CXRS spectra of the 5291-Å line. The time behavior of the ion temperature profile in different ohmic heating modes is studied. The temperature profile dependence on the ECRH power is measured, and the dynamics of ECR removal of carbon nuclei from the T-10 plasma is described. Experimental data from the CXRS diagnostics at T-10 substantially contribute to the implementation of physical programs of studies on heat and particle transport in tokamak plasmas and investigation of geodesic acoustic mode properties.

Diagnostic techniques in deflagration and detonation studies.

PubMed

Proud, William G; Williamson, David M; Field, John E; Walley, Stephen M

2015-12-01

Advances in experimental, high-speed techniques can be used to explore the processes occurring within energetic materials. This review describes techniques used to study a wide range of processes: hot-spot formation, ignition thresholds, deflagration, sensitivity and finally the detonation process. As this is a wide field the focus will be on small-scale experiments and quantitative studies. It is important that such studies are linked to predictive models, which inform the experimental design process. The stimuli range includes, thermal ignition, drop-weight, Hopkinson Bar and Plate Impact studies. Studies made with inert simulants are also included as these are important in differentiating between reactive response and purely mechanical behaviour.

Stochastic Nature in Cellular Processes

NASA Astrophysics Data System (ADS)

Liu, Bo; Liu, Sheng-Jun; Wang, Qi; Yan, Shi-Wei; Geng, Yi-Zhao; Sakata, Fumihiko; Gao, Xing-Fa

2011-11-01

The importance of stochasticity in cellular processes is increasingly recognized in both theoretical and experimental studies. General features of stochasticity in gene regulation and expression are briefly reviewed in this article, which include the main experimental phenomena, classification, quantization and regulation of noises. The correlation and transmission of noise in cascade networks are analyzed further and the stochastic simulation methods that can capture effects of intrinsic and extrinsic noise are described.

Experimente ueber den Einflusse von Metaboliten und Antimetaboliten am Modell von Trichomonas Vaginalis. I. Mitteilung Experimente mit dem Vitamin B2-Komplex (Experiments on the Influence of Metabolites and Antimetabolites on the Model of Trichomonas vaginalis. I. Communication: Experiments with the Vitamin-B2-Complex),

DTIC Science & Technology

pathogenic protozoa Trichomonas vaginalis have been studied. Material and methods are described in the paper. The efficacy of the individual admixtures from the vitamin-B2-complex is subsequently discussed. (Author)

Physiology of Oxygen Breathing in Pilots: A Brief Review

DTIC Science & Technology

2018-03-23

brief review Abstract This non-exhaustive survey presents literature describing some effects of breathing oxygen partial pressures between...CG, J Butler, AB DuBois (1959). Some effects of restriction of chest cage expansion on pulmonary function in man: an experimental study. J Clin...Effects of Submerged Breathing of Air or Oxygen. Navy Experimental Diving Unit TR 02-14, Panama City, FL. http://archive.rubicon- foundation.org/3483

Cognitive Synergy in Multimedia Learning

ERIC Educational Resources Information Center

Kim, Daesang; Kim, Dong-Joong; Whang, Woo-Hyung

2013-01-01

The main focus of our study was to investigate multimedia effects that had different results from the findings of existing multimedia learning studies. First, we describe and summarize three experimental studies we conducted from 2006 to 2010. Then we analyze our findings to explore learner characteristics that may impact the cognitive processes…

Numerical and experimental study of electron-beam coatings with modifying particles FeB and FeTi

NASA Astrophysics Data System (ADS)

Kryukova, Olga; Kolesnikova, Kseniya; Gal'chenko, Nina

2016-07-01

An experimental study of wear-resistant composite coatings based on titanium borides synthesized in the process of electron-beam welding of components thermo-reacting powders are composed of boron-containing mixture. A model of the process of electron beam coating with modifying particles of boron and titanium based on physical-chemical transformations is supposed. The dissolution process is described on the basis of formal kinetic approach. The result of numerical solution is the phase and chemical composition of the coating under nonequilibrium conditions, which is one of the important characteristics of the coating forming during electron beam processing. Qualitative agreement numerical calculations with experimental data was shown.

AMPS data management concepts. [Atmospheric, Magnetospheric and Plasma in Space experiment

NASA Technical Reports Server (NTRS)

Metzelaar, P. N.

1975-01-01

Five typical AMPS experiments were formulated to allow simulation studies to verify data management concepts. Design studies were conducted to analyze these experiments in terms of the applicable procedures, data processing and displaying functions. Design concepts for AMPS data management system are presented which permit both automatic repetitive measurement sequences and experimenter-controlled step-by-step procedures. Extensive use is made of a cathode ray tube display, the experimenters' alphanumeric keyboard, and the computer. The types of computer software required by the system and the possible choices of control and display procedures available to the experimenter are described for several examples. An electromagnetic wave transmission experiment illustrates the methods used to analyze data processing requirements.

Psychology's Renaissance.

PubMed

Nelson, Leif D; Simmons, Joseph; Simonsohn, Uri

2018-01-04

In 2010-2012, a few largely coincidental events led experimental psychologists to realize that their approach to collecting, analyzing, and reporting data made it too easy to publish false-positive findings. This sparked a period of methodological reflection that we review here and call Psychology's Renaissance. We begin by describing how psychologists' concerns with publication bias shifted from worrying about file-drawered studies to worrying about p-hacked analyses. We then review the methodological changes that psychologists have proposed and, in some cases, embraced. In describing how the renaissance has unfolded, we attempt to describe different points of view fairly but not neutrally, so as to identify the most promising paths forward. In so doing, we champion disclosure and preregistration, express skepticism about most statistical solutions to publication bias, take positions on the analysis and interpretation of replication failures, and contend that meta-analytical thinking increases the prevalence of false positives. Our general thesis is that the scientific practices of experimental psychologists have improved dramatically.

76 FR 25674 - Notice of Submission for OMB Review

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-05

... for the rigorous comparative interrupted time series design including student records data collection...- experimental designs to explore the relationship between magnet programs and student achievement both for... this study. An OMB clearance request that (1) described the study design and full data collection...

Rain Garden Research at EPA’s Urban Watershed Research Facility

EPA Science Inventory

Summary of the ongoing rain garden research at UWMB. The context for the study was described as well as the experimental design for the full-scale study, instrumentation, and stormwater collection system. Supporting bench scale research on hydraulic properties of media and soil...

EPA (ENVIRONMENTAL PROTECTION AGENCY) METHOD STUDY 28, PCB'S (POLYCHLORINATED BIPHENYLS) IN OIL

EPA Science Inventory

This report describes the experimental design and the results of the validation study for two analytical methods to detect polychlorinated byphenyls in oil. The methods analyzed for four PCB Aroclors (1016, 1242, 1254, and 1260), 2-chlorobiphenyl, and decachlorobiphenyl. The firs...

Quasi-experimental study designs series-paper 11: supporting the production and use of health systems research syntheses that draw on quasi-experimental study designs.

PubMed

Lavis, John N; Bärnighausen, Till; El-Jardali, Fadi

2017-09-01

To describe the infrastructure available to support the production of policy-relevant health systems research syntheses, particularly those incorporating quasi-experimental evidence, and the tools available to support the use of these syntheses. Literature review. The general challenges associated with the available infrastructure include their sporadic nature or limited coverage of issues and countries, whereas the specific ones related to policy-relevant syntheses of quasi-experimental evidence include the lack of mechanism to register synthesis titles and scoping review protocols, the limited number of groups preparing user-friendly summaries, and the difficulty of finding quasi-experimental studies for inclusion in rapid syntheses and research syntheses more generally. Although some new tools have emerged in recent years, such as guidance workbooks and citizen briefs and panels, challenges related to using available tools to support the use of policy-relevant syntheses of quasi-experimental evidence arise from such studies potentially being harder for policymakers and stakeholders to commission and understand. Policymakers, stakeholders, and researchers need to expand the coverage and institutionalize the use of the available infrastructure and tools to support the use of health system research syntheses containing quasi-experimental evidence. Copyright © 2017 Elsevier Inc. All rights reserved.

A millimeter wave quasi-optical mixer and multiplier

NASA Technical Reports Server (NTRS)

1977-01-01

The results of an experimental study of a biconical quasi-optical Schottky barrier diode mount design which could be used for mixing and multiplying in the frequency range 200-1000 Ghz are reported. The biconical mount is described and characteristics measured at 185 Ghz are presented. The use of the mount for quasi-optical frequency doubling from 56 to 112 Ghz is described and efficiency estimates given.

Functional Utilization of DABS Data Link Discrete Address Beacon System

DOT National Transportation Integrated Search

1978-10-01

The report describes the output of a Task Force established by FAA Headquarters, SRDS, Robert Wedan, in June 1977 to study and recommend potential applications for Data Link to the DABS Experimentation Program

Space weightlessness and hormonal changes in human subjects and experimental animals

NASA Technical Reports Server (NTRS)

Grindeland, R. E.

1982-01-01

Data from spaceflight and bed rest studies are briefly described and the difficulties in interpreting these results are discussed. Growth hormone, prolactin, adrenocorticotropic hormone, cortisol, insulin, aldosterone, and other hormones are addressed.

Elastic suspension of a wind tunnel test section

NASA Technical Reports Server (NTRS)

Hacker, R.; Rock, S.; Debra, D. B.

1982-01-01

Experimental verification of the theory describing arbitrary motions of an airfoil is reported. The experimental apparatus is described. A mechanism was designed to provide two separate degrees of freedom without friction or backlash to mask the small but important aerodynamic effects of interest.

A new cannulation method for isolated mitral valve surgery--"apicoaortic-pa" cannulation.

PubMed

Wada, J; Komatsu, S; Nakae, S; Kazui, T

1976-06-01

The present paper describes experimental and clinical studies of a new method "Apicoaortic-PA" cannulation for mitral valve surgery. Our experimental study showed that this method was more rapid and more physiological for cardiopulmonary bypass. We used this technique in 55 cases of isolated mitral valve surgery with successful results. Our general philosophy of surgical approach to the mitral valve diseases is also discussed. We advocate the utilization of the "Apicoaortic Pulmonary Artery" cannulation method for clinical use in isolated mitral valve surgery through the left thoracotomy.

Noise characteristics of upper surface blown configurations: Analytical Studies

NASA Technical Reports Server (NTRS)

Reddy, N. N.; Tibbetts, J. G.; Pennock, A. P.; Tam, C. K. W.

1978-01-01

Noise and flow results of upper surface blown configurations were analyzed. The dominant noise source mechanisms were identified from experimental data. From far-field noise data for various geometric and operational parameters, an empirical noise prediction program was developed and evaluated by comparing predicted results with experimental data from other tests. USB aircraft compatibility studies were conducted using the described noise prediction and a cruise performance data base. A final design aircraft was selected and theory was developed for the noise from the trailing edge wake assuming it as a highly sheared layer.

A multichannel scala tympani electrode array incorporating a drug delivery system for chronic intracochlear infusion.

PubMed

Shepherd, Robert K; Xu, Jin

2002-10-01

We have developed a novel scala tympani electrode array suitable for use in experimental animals. A unique feature of this array is its ability to chronically deliver pharmacological agents to the scala tympani. The design of the electrode array is described in detail. Experimental studies performed in guinea pigs confirm that this array can successfully deliver various drugs to the cochlea while chronically stimulating the auditory nerve.

Knudsen Cell Studies of Ti-Al Thermodynamics

NASA Technical Reports Server (NTRS)

Jacobson, Nathan S.; Copland, Evan H.; Mehrotra, Gopal M.; Auping, Judith; Gray, Hugh R. (Technical Monitor)

2002-01-01

In this paper we describe the Knudsen cell technique for measurement of thermodynamic activities in alloys. Numerous experimental details must be adhered to in order to obtain useful experimental data. These include introduction of an in-situ standard, precise temperature measurement, elimination of thermal gradients, and precise cell positioning. Our first design is discussed and some sample data on Ti-Al alloys is presented. The second modification and associated improvements are also discussed.

Ultrafiltration membrane reactors for enzymatic resolution of amino acids: design model and optimization.

PubMed

Bódalo, A; Gómez, J L.; Gómez, E; Bastida, J; Máximo, M F.; Montiel, M C.

2001-03-08

In this paper the possibility of continuous resolution of DL-phenylalanine, catalyzed by L-aminoacylase in a ultrafiltration membrane reactor (UFMR) is presented. A simple design model, based on previous kinetic studies, has been demonstrated to be capable of describing the behavior of the experimental system. The model has been used to determine the optimal experimental conditions to carry out the asymmetrical hydrolysis of N-acetyl-DL-phenylalanine.

Experimental Overview of the Search for Chiral Effects at RHIC

NASA Astrophysics Data System (ADS)

Wang, Gang

2017-01-01

In high-energy heavy-ion collisions, various novel transport phenomena in local chiral domains result from the interplay of quantum anomalies with magnetic field and vorticity, and could survive the expansion of the fireball and be detected in experiments. Among these phenomena are the chiral magnetic effect, the chiral vortical effect and the chiral magnetic wave, the experimental searches for which have aroused extensive interest. This review will describe the current status of experimental studies at Relativistic Heavy Ion Collider at BNL, and outline the future work in experiment needed to eliminate the existing uncertainties in the interpretation of the data.

Experimental Keratitis Due to Pseudomonas aeruginosa: Model for Evaluation of Antimicrobial Drugs

PubMed Central

Davis, Starkey D.; Chandler, John W.

1975-01-01

An improved method for experimental keratitis due to Pseudomonas aeruginosa is described. Essential features of the method are use of inbred guinea pigs, intracorneal injection of bacteria, subconjunctival injection of antibiotics, “blind” evaluation of results, and statistical analysis of data. Untreated ocular infections were most severe 5 to 7 days after infection. Sterilized bacterial suspensions caused no abnormalities on day 5. Tobramycin and polymyxin B were more active than gentamicin against two strains of Pseudomonas. This model is suitable for many types of quantitative studies on experimental keratitis. Images PMID:810084

Numerical and experimental study of a hydrodynamic cavitation tube

NASA Astrophysics Data System (ADS)

Hu, H.; Finch, J. A.; Zhou, Z.; Xu, Z.

1998-08-01

A numerical analysis of hydrodynamics in a cavitation tube used for activating fine particle flotation is described. Using numerical procedures developed for solving the turbulent k-ɛ model with boundary fitted coordinates, the stream function, vorticity, velocity, and pressure distributions in a cavitation tube were calculated. The calculated pressure distribution was found to be in excellent agreement with experimental results. The requirement of a pressure drop below approximately 10 m water for cavitation to occur was observed experimentally and confirmed by the model. The use of the numerical procedures for cavitation tube design is discussed briefly.

76 FR 10573 - Notice of Proposed Information Collection Requests

Federal Register 2010, 2011, 2012, 2013, 2014

2011-02-25

... study will use quasi- experimental designs to explore the relationship between magnet programs and... that (1) described the study design and full data collection activities and (2) requested approval for... associated with the fourth and fifth year of data collection necessary for the rigorous comparative...

Vitamin C: Rate of Decay and Stability Characteristics

ERIC Educational Resources Information Center

Kakis, Frederic J.; Rossi, Carl J.

1974-01-01

Describes an experiment designed to provide the opportunity for studying some of the parameters affecting the stability of Vitamin C in various environments, and to acquaint the student with an experimental procedure for studying simple reaction kinetics and the calculations of specific rate constants. (Author/JR)

Experimental equipment for measuring of rotary air motors parameters

NASA Astrophysics Data System (ADS)

Dvořák, Lukáš; Fojtášek, Kamil; Řeháček, Vojtěch

In the article the construction of an experimental device for measuring the parameters of small rotary air motors is described. Further a measurement methodology and measured data processing are described. At the end of the article characteristics of the chosen air motor are presented.

Correlation Analysis of Experimental Remote-Sensing Data and Models of Microwave Rough Sea-Surface Emission

NASA Astrophysics Data System (ADS)

Sazonov, D. S.

2017-12-01

A correlation analysis of the model calculations and experimental measurements of wind-speed sensitivity of a rough sea-surface microwave emission at a frequency of 37.5 GHz are presented. The field data used in the research were collected over 3 years in the summer and autumn periods at the oceanographic platform of the Marine Hydrophysical Institute, Russian Academy of Sciences (RAS). A hypothesis about a significant correlation between the model calculations and experimentally measured sea-surface emission ability caused by wind forcing was formulated and tested to reveal this correlation. An evaluation of the discrepancy between the model and experimental data has been performed by an analysis of residuals. Our studies have shown that among the selected models not a single one adequately describes the experimental data.

[Some notes on the history of the experimental surgery laboratory. Reflections on its relevance in education and surgical research].

PubMed

de la Garza-Rodea, Anabel Sofía; Padilla-Sánchez, Luis; de la Garza-Aguilar, Javier; Neri-Vela, Rolando

2007-01-01

The progress of medicine has largely been due to research, and for surgery, in particular, the experimental surgical laboratory has been considered fundamental to the surgeon's education. In this study, a general view of experimental surgery is given in animal models based on bioethical norms as well as to design, create and apply different surgical procedures before performing in humans. Experimental surgery also facilitates surgical teaching and promotes the surgeon's scientific reasoning. Methods. This is a retrospective and descriptive study. Data were collected from direct and indirect sources of available publications on the historical, bioethical and educational aspects of medicine, focusing on surgery. The important facts corresponding to the field of experimental surgery and applicable in Mexico were selected. Concepts of experimental surgical models and of the experimental surgery laboratory were described. Bioethical considerations are emphasized for care of experimental animals. Finally, this work focuses on the importance of surgical experimentation in current and future development of the surgical researcher. Conclusions. Experimentation with animal models in a surgical laboratory is essential for surgical teaching and promotes development of the scientific thought in the surgeon. It is necessary for surgical research and is fundamental for making progress in surgery, treatment and medicine as science.

Characterization and modeling of an advanced flexible thermal protection material for space applications

NASA Technical Reports Server (NTRS)

Clayton, Joseph P.; Tinker, Michael L.

1991-01-01

This paper describes experimental and analytical characterization of a new flexible thermal protection material known as Tailorable Advanced Blanket Insulation (TABI). This material utilizes a three-dimensional ceramic fabric core structure and an insulation filler. TABI is the leading candidate for use in deployable aeroassisted vehicle designs. Such designs require extensive structural modeling, and the most significant in-plane material properties necessary for model development are measured and analytically verified in this study. Unique test methods are developed for damping measurements. Mathematical models are developed for verification of the experimental modulus and damping data, and finally, transverse properties are described in terms of the inplane properties through use of a 12-dof finite difference model of a simple TABI configuration.

Chemical reacting flows

NASA Astrophysics Data System (ADS)

Lezberg, Erwin A.; Mularz, Edward J.; Liou, Meng-Sing

1991-03-01

The objectives and accomplishments of research in chemical reacting flows, including both experimental and computational problems are described. The experimental research emphasizes the acquisition of reliable reacting-flow data for code validation, the development of chemical kinetics mechanisms, and the understanding of two-phase flow dynamics. Typical results from two nonreacting spray studies are presented. The computational fluid dynamics (CFD) research emphasizes the development of efficient and accurate algorithms and codes, as well as validation of methods and modeling (turbulence and kinetics) for reacting flows. Major developments of the RPLUS code and its application to mixing concepts, the General Electric combustor, and the Government baseline engine for the National Aerospace Plane are detailed. Finally, the turbulence research in the newly established Center for Modeling of Turbulence and Transition (CMOTT) is described.

An Overview of an Experimental Demonstration Aerotow Program

NASA Technical Reports Server (NTRS)

Murray, James E.; Bowers, Albion H.; Lokos, William A.; Peters, Todd L.; Gera, Joseph

1998-01-01

An overview of an experimental demonstration of aerotowing a delta-wing airplane with low-aspect ratio and relatively high wing loading is presented. Aerotowing of future space launch configurations is a new concept, and the objective of the work described herein is to demonstrate the aerotow operation using an airplane configuration similar to conceptual space launch vehicles. Background information on the use of aerotow for a space launch vehicle is presented, and the aerotow system used in this demonstration is described. The ground tests, analytical studies, and flight planning used to predict system behavior and to enhance flight safety are detailed. The instrumentation suite and flight test maneuvers flown are discussed, preliminary performance is assessed, and flight test results are compared with the preflight predictions.

Control of flexible beams using a free-free active truss

NASA Technical Reports Server (NTRS)

Clark, W. W.; Kimiavi, B.; Robertshaw, H. H.

1989-01-01

An analytical and experimental study involving controlling flexible beams using a free-free active truss is presented. This work extends previous work in controlling flexible continua with active trusses which were configured with fixed-free boundary conditions. The following describes the Lagrangian approach used to derive the equations of motion for the active truss and the beams attached to it. A partial-state feedback control law is derived for this system based on a full-state feedback Linear Quadratic Regulator method. The analytical model is examined via numerical simulations and the results are compared to a similar experimental apparatus described herein. The results show that control of a flexible continua is possible with a free-free active truss.

42 CFR 405.212 - Medicare Coverage IDE study criteria.

Code of Federal Regulations, 2014 CFR

2014-10-01

... Medicare coverage of items and services described in § 405.211, a Category A (Experimental) or Category B...) The study design is methodologically appropriate and the anticipated number of enrolled subjects is... CFR parts 50, 56, and 812 and 45 CFR part 46. (7) Where appropriate, the study is not designed to...

Automated array assembly

NASA Technical Reports Server (NTRS)

Daiello, R. V.

1977-01-01

A general technology assessment and manufacturing cost analysis was presented. A near-term (1982) factory design is described, and the results of an experimental production study for the large-scale production of flat-panel silicon and solar-cell arrays are detailed.

A Simplified Integrated Fish Culture Hydroponics System.

ERIC Educational Resources Information Center

Emberger, Gary

1991-01-01

Investigations that facilitate experimental design, the concept of replication, data analysis, and other aspects of scientific study are described. A list of materials, the recommended plants, and the directions for building the hydroponics unit are included. (KR)

Studies of uranium-sodium suspensions. Part I. Construction and operation of experimental loop

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bett, F L; Hilditch, R J; Mepham, R G

1961-08-01

An experimnental uranium- sodium suspension loop was operated for 4320 hr. The design, construction, commissioning, and operation of the loop to the point where a comnplete stable suspension was obtained is described.

Experimental Studies of the He-Ne Laser: Resonators and Self-Locking.

ERIC Educational Resources Information Center

Ruddock, I. S.

1980-01-01

He-Ne laser experiments suitable for an undergraduate laboratory are described. The topics covered are cavity stability, self-mode-locking coherent interactions between pulses and laser medium, and spontaneous transverse mode locking. (Author/DS)

Animal Watching: Outdoors and In.

ERIC Educational Resources Information Center

McLure, John W.

2001-01-01

Describes using domesticated, wild, or feral animals to teach students about nature and animal behavior. Connections can be made with psychology, economics, genetics, history, art, and other disciplines. The study of animal behavior provides opportunities for harmless student experimentation. (SAH)

Studies of electron-molecule collisions - Applications to e-H2O

NASA Technical Reports Server (NTRS)

Brescansin, L. M.; Lima, M. A. P.; Gibson, T. L.; Mckoy, V.; Huo, W. M.

1986-01-01

Elastic differential and momentum transfer cross sections for the elastic scattering of electrons by H2O are reported for collision energies from 2 to 20 eV. These fixed-nuclei static-exchange cross sections were obtained using the Schwinger variational approach. In these studies the exchange potential is directly evaluated and not approximated by local models. The calculated differential cross sections, obtained with a basis set expansion of the scattering wave function, agree well with available experimental data at intermediate and larger angles. As used here, the results cannot adequately describe the divergent cross sections at small angles. An interesting feature of the calculated cross sections, particularly at 15 and 20 eV, is their significant backward peaking. This peaking occurs in the experimentally inaccessible region beyond a scattering angle of 120 deg. The implication of this feature for the determination of momentum transfer cross sections is described.

Modeling biosorption of Cr(VI) onto Ulva compressa L. from aqueous solutions.

PubMed

Aid, Asma; Amokrane, Samira; Nibou, Djamel; Mekatel, Elhadj; Trari, Mohamed; Hulea, Vasile

2018-01-01

The marine biomass Ulva compressa L. (ECL) was used as a low-cost biosorbent for the removal of Cr(VI) from contaminated aqueous solutions. The operating variables were optimized: pH ∼ 2, initial concentration of 25 mg/L, solid/liquid ratio of 6 g/L and a temperature of 50 °C, leading to an uptake elimination of 96%. A full factorial experimental design technique enabled us to obtain a mathematical model describing the Cr(VI) biosorption and to study the main effects and interactions among operational parameters. The equilibrium isotherm was analyzed by the Langmuir, Freundlich and Dubinin-Radushkevich (D-R) models; it has been found that the adsorption process follows well the Langmuir model. Kinetic studies showed that the pseudo-second order model describes suitably the experimental data. The thermodynamic parameters indicated an endothermic heat and a spontaneity of the Cr(VI) biosorption onto ECL.

QSAR studies in substituted 1,2,3,4,6,7,12,12a-octa-hydropyrazino[2',1':6,1]pyrido[3,4-b]indoles--a potent class of neuroleptics.

PubMed

Saxena, Anil K; Ram, Siya; Saxena, Mridula; Singh, Nidhi; Prathipati, Philip; Jain, Padam C; Singh, H K; Anand, Nitya

2003-05-01

A series of nineteen substituted 1,2,3,4,6,7,12,12a-octahydropyrazino[2',1':6,1]pyrido[3, 4-b]indoles analogues of neuroleptic drug, Centbutindole have been studied using quantitative structure-activity relationship analysis. The derived models display good fits to the experimental data (r>or=0.75) having good predictive power (r(cv)>or=0.688). The best model describes a high correlation between predicted and experimental activity data (r=0.967). Statistical analysis of the equation populations indicates that hydrophobicity (as measured by pi(R), logP(o/w) and SlogP_VSA8), dipole y and structural parameters in terms of indicator variable, (In(1)) and globularity are important variables in describing the variation in the neuroleptic activity in the series.

The theoretical and experimental study of a material structure evolution in gigacyclic fatigue regime

NASA Astrophysics Data System (ADS)

Plekhov, Oleg; Naimark, Oleg; Narykova, Maria; Kadomtsev, Andrey; Betekhtin, Vladimir

2015-10-01

The work is devoted to the study of the metal structure evolution under gigacyclic fatigue (VHCF) regime. The study of the mechanical properties of the samples (Armco iron) with different state of life time existing was carried out on the base of the acoustic resonance method. The damage accumulation (porosity of the samples) was studied by the hydrostatic weighing method. A statistical model of damage accumulation was proposed in order to describe the damage accumulation process. The model describes the influence of the sample surface on the location of fatigue crack initiation.

Exploratory studies of the cruise performance of upper surface blown configurations. Experimental program: Test facilities, model design instrumentation, and lowspeed, high-lift tests

NASA Technical Reports Server (NTRS)

Braden, J. A.; Hancock, J. P.; Burdges, K. P.; Hackett, J. E.

1980-01-01

The model hardware, test facilities and instrumentation utilized in an experimental study of upper surface blown configurations at cruise is described. The high speed (subsonic) experimental work, studying the aerodynamic effects of wing nacelle geometric variations, was conducted around semispan model configurations composed of diversified, interchangeable components. Power simulation was provided by high pressure air ducted through closed forebody nacelles. Nozzle geometry was varied across size, exit aspect ratio, exit position and boattail angle. Three dimensional force and two dimensional pressure measurements were obtained at cruise Mach numbers from 0.5 to 0.8 and at nozzle pressure ratios up to about 3.0. The experimental investigation was supported by an analytical synthesis of the system using a vortex lattice representation with first order power effects. Results are also presented from a compatibility study in which a short haul transport is designed on the basis of the aerodynamic findings in the experimental study as well as acoustical data obtained in a concurrent program. High lift test data are used to substantiate the projected performance of the selected transport design.

Steam cycle of the FR2 (in German)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Perinic, D.; Schmidt, T.

1973-01-01

Following a brief explanation of the requirement of the experimental circuit, the use of irradiation and the circuit are described in detail. The installed experimental equipment within the test circuit is described and the safety problems discussed. The operation of the test equipment is summarized. (GE)

Effectiveness of Facebook Based Learning to Enhance Creativity among Islamic Studies Students by Employing Isman Instructional Design Model

ERIC Educational Resources Information Center

Alias, Norlidah; Siraj, Saedah; Daud, Mohd Khairul Azman Md; Hussin, Zaharah

2013-01-01

The study examines the effectiveness of Facebook based learning to enhance creativity among Islamic Studies students in the secondary educational setting in Malaysia. It describes the design process by employing the Isman Instructional Design Model. A quantitative study was carried out using experimental method and background survey. The…

Secondary wastewater polishing with ultrafiltration membranes for unrestricted reuse: fouling and flushing modeling.

PubMed

Gillerman, Leonid; Bick, Amos; Buriakovsky, Nisan; Oron, Gideon

2006-11-01

The effects of operating parameters such astransmembrane pressure, retentate, and recirculation volumetric flow rates on the productivity of an ultrafiltration membrane were studied using field data and development of a management model. Correlation equations for predicting the volumetric permeate flow rates were derived from general membrane blocking laws and experimental data. The experimental data were obtained from a pilot study carried out in the Arad wastewater treatment system (a pilot plant operating in feed and bleed operation mode) located several kilometers west of the City of Arad, Israel. Correlation predictions were confirmed with the independent experimental results. The results enabled us to develop a mathematical expression accurately describing the decline in flux due to fouling.

Experimental study of the separating confluent boundary-layer. Volume 2: Experimental data

NASA Technical Reports Server (NTRS)

Braden, J. A.; Whipkey, R. R.; Jones, G. S.; Lilley, D. E.

1983-01-01

An experimental low speed study of the separating confluent boundary layer on a NASA GAW-1 high lift airfoil is described. The airfoil was tested in a variety of high lift configurations comprised of leading edge slat and trailing edge flap combinations. The primary test instrumentation was a two dimensional laser velocimeter (LV) system operating in a backscatter mode. Surface pressures and corresponding LV derived boundary layer profiles are given in terms of velocity components, turbulence intensities and Reynolds shear stresses as characterizing confluent boundary layer behavior up to and beyond stall. LV derived profiles and associated boundary layer parameters and those obtained from more conventional instrumentation such as pitot static transverse, Preston tube measurements and hot-wire surveys are compared.

Electron impact ionization of metastable 2P-state hydrogen atoms in the coplanar geometry

NASA Astrophysics Data System (ADS)

Dhar, S.; Nahar, N.

Triple differential cross sections (TDCS) for the ionization of metastable 2P-state hydrogen atoms by electrons are calculated for various kinematic conditions in the asymmetric coplanar geometry. In this calculation, the final state is described by a multiple-scattering theory for ionization of hydrogen atoms by electrons. Results show qualitative agreement with the available experimental data and those of other theoretical computational results for ionization of hydrogen atoms from ground state, and our first Born results. There is no available other theoretical results and experimental data for ionization of hydrogen atoms from the 2P state. The present study offers a wide scope for the experimental study for ionization of hydrogen atoms from the metastable 2P state.

[Research-oriented experimental course of plant cell and gene engineering for undergraduates].

PubMed

Xiaofei, Lin; Rong, Zheng; Morigen, Morigen

2015-04-01

Research-oriented comprehensive experimental course for undergraduates is an important part for their training of innovation. We established an optional course of plant cell and gene engineering for undergraduates using our research platform. The course is designed to study the cellular and molecular basis and experimental techniques for plant tissue culture, isolation and culture of protoplast, genetic transformation, and screening and identification of transgenic plants. To develop undergraduates' ability in experimental design and operation, and inspire their interest in scientific research and innovation consciousness, we integrated experimental teaching and practice in plant genetic engineering on the tissue, cellular, and molecular levels. Students in the course practiced an experimental teaching model featured by two-week teaching of principles, independent experimental design and bench work, and ready-to-access laboratory. In this paper, we describe the contents, methods, evaluation system and a few issues to be solved in this course, as well as the general application and significance of the research-oriented experimental course in reforming undergraduates' teaching and training innovative talents.

Assessing Team Learning in Technology-Mediated Collaboration: An Experimental Study

ERIC Educational Resources Information Center

Andres, Hayward P.; Akan, Obasi H.

2010-01-01

This study examined the effects of collaboration mode (collocated versus non-collocated videoconferencing-mediated) on team learning and team interaction quality in a team-based problem solving context. Situated learning theory and the theory of affordances are used to provide a framework that describes how technology-mediated collaboration…

The Program of Special Directed Studies: A Five Year Summary.

ERIC Educational Resources Information Center

Mornell, Eugene S.

The report described one relatively small but extensively researched special admission and compensatory education program at The Claremont Colleges, California. The Program of Special Directed Studies for Transition to College (PSDS) was administered by the Claremont University Center. PSDS was a 5-year experimental project primarily funded by the…

An Analysis of Student Choices in Medical Ethical Dilemmas.

ERIC Educational Resources Information Center

Woloshin, Phyllis Lerman

This report describes a study undertaken to assess student choices in medical ethical dilemmas. Medical ethical dilemmas are interpreted to include problems such as abortion, euthanasia, sterilization, experimentation on humans, allocation of scarce medical resources, and physician and health personnel training. The major purpose of the study was…

Propeller study. Part 3: Experimental determination of thrust and torque on the YO-3A aircraft

NASA Technical Reports Server (NTRS)

Ormsbee, A. I.; Siddiqi, S. A.; Sivier, K. R.

1977-01-01

Instrumentation and procedures for obtaining in-flight measurements of the torque and thrust of a propeller mounted on a YO-3A aircraft are described. Problems encountered in the study are discussed and methods for eliminating these difficulties are suggested.

The Warm-Cold Study: A Classroom Demonstration of Impression Formation.

ERIC Educational Resources Information Center

Symbaluk, Diane G.; Cameron, Judy

1998-01-01

Describes a procedure for teaching experimental design to students in the social sciences. Argues that by replicating Solomon Asch's and H. Kelley's classic studies on impression formation, students learn how to conduct experiments, analyze data, and evaluate the significance of research. Provides instructions for implementing the strategy. (DSK)

CHARACTERIZATION OF EMISSIONS FORM CARPET SAMPLES USING A 10-GALLON AQUARIUM AS THE SOURCE CHAMBER

EPA Science Inventory

The report discusses part of a Phase I carpet bioresponse study sponsored by EPA. he study evaluated emissions from carpet samples that had previously been reported to show toxic effects on experimental mice. he report describes the major findings of only the chemical characteriz...

CHARACTERIZATION OF EMISSIONS FROM CARPET SAMPLES USING A 10-GALLON AQUARIUM AS THE SOURCE CHAMBER

EPA Science Inventory

The report discusses part of a Phase I carpet bioresponse study sponsored by EPA. he study evaluated emissions from carpet samples that had previously been reported to show toxic effects on experimental mice. he report describes the major findings of only the chemical characteriz...

Advanced technology development multi-color holography

NASA Technical Reports Server (NTRS)

Vikram, Chandra S.

1993-01-01

This is the final report of the Multi-color Holography project. The comprehensive study considers some strategic aspects of multi-color holography. First, various methods of available techniques for accurate fringe counting are reviewed. These are heterodyne interferometry, quasi-heterodyne interferometry, and phase-shifting interferometry. Phase-shifting interferometry was found to be the most suitable for multi-color holography. Details of experimentation with a sugar solution are also reported where better than 1/200 of a fringe order measurement capability was established. Rotating plate glass phase shifter was used for the experimentation. The report then describes the possible role of using more than two wavelengths with special reference-to-object beam intensity ratio needs in multicolor holography. Some specific two- and three-color cases are also described in detail. Then some new analysis methods of the reconstructed wavefront are considered. These are deflectometry, speckle metrology, confocal optical signal processing, and phase shifting technique related applications. Finally, design aspects of an experimental breadboard are presented.

Issues and approach to develop validated analysis tools for hypersonic flows: One perspective

NASA Technical Reports Server (NTRS)

Deiwert, George S.

1993-01-01

Critical issues concerning the modeling of low density hypervelocity flows where thermochemical nonequilibrium effects are pronounced are discussed. Emphasis is on the development of validated analysis tools, and the activity in the NASA Ames Research Center's Aerothermodynamics Branch is described. Inherent in the process is a strong synergism between ground test and real gas computational fluid dynamics (CFD). Approaches to develop and/or enhance phenomenological models and incorporate them into computational flowfield simulation codes are discussed. These models were partially validated with experimental data for flows where the gas temperature is raised (compressive flows). Expanding flows, where temperatures drop, however, exhibit somewhat different behavior. Experimental data for these expanding flow conditions is sparse and reliance must be made on intuition and guidance from computational chemistry to model transport processes under these conditions. Ground based experimental studies used to provide necessary data for model development and validation are described. Included are the performance characteristics of high enthalpy flow facilities, such as shock tubes and ballistic ranges.

Hydrodynamic Aspects of Particle Clogging in Porous Media

PubMed Central

MAYS, DAVID C.; HUNT, JAMES R.

2010-01-01

Data from 6 filtration studies, representing 43 experiments, are analyzed with a simplified version of the single-parameter O’Melia and Ali clogging model. The model parameter displays a systematic dependence on fluid velocity, which was an independent variable in each study. A cake filtration model also explains the data from one filtration study by varying a single, velocity-dependent parameter, highlighting that clogging models, because they are empirical, are not unique. Limited experimental data indicate exponential depth dependence of particle accumulation, whose impact on clogging is quantified with an extended O’Melia and Ali model. The resulting two-parameter model successfully describes the increased clogging that is always observed in the top segment of a filter. However, even after accounting for particle penetration, the two-parameter model suggests that a velocity-dependent parameter representing deposit morphology must also be included to explain the data. Most of the experimental data are described by the single-parameter O’Melia and Ali model, and the model parameter is correlated to the collector Peclet number. PMID:15707058

Molecular photoionization processes of astrophysical and aeronomical interest

NASA Technical Reports Server (NTRS)

Langhoff, P. W.

1985-01-01

An account is given of aspects of photoionization processes in molecules, with particular reference to recent theoretical and experimental studies of partial cross sections for production of specific final electronic states and of parent and fragment ions. Such cross sections help provide a basis for specifying the state of excitation of the ionized medium, are useful for estimating the kinetic energy distributions of photoejected electrons and fragment ions, provide parent-and fragment-ion yields, and clarify the possible origins of neutral fragments in highly excited rovibronic states. A descriptive account is given of photoionization phenomena, including tabulation of valence- and inner-shell potentials for some molecules of astrophysical and aeronomical interest. Cross sectional expressions are given. Various approximations currently employed in computational studies are described briefly, threshold laws and high-energy limits are indicated, and distinction is drawn between resonant and direct photoionization phenomena. Recent experimental and theoretical studies of partial photoionization cross sections in selected compounds of astrophysical and aeronomical relevance are described and discussed.

Modelling wastewater treatment in a submerged anaerobic membrane bioreactor.

PubMed

Spagni, Alessandro; Ferraris, Marco; Casu, Stefania

2015-01-01

Mathematical modelling has been widely applied to membrane bioreactor (MBRs) processes. However, to date, very few studies have reported on the application of the anaerobic digestion model N.1 (ADM1) to anaerobic membrane processes. The aim of this study was to evaluate the applicability of the ADM1 to a submerged anaerobic MBR (SAMBR) treating simulated industrial wastewater composed of cheese whey and sucrose. This study demonstrated that the biological processes involved in SAMBRs can be modelled by using the ADM1. Moreover, the results showed that very few modifications of the parameters describing the ADM1 were required to reasonably fit the experimental data. In particular, adaptation to the specific conditions of the coefficients describing the wastewater characterisation and the reduction of the hydrolysis rate of particulate carbohydrate (khyd,ch) from 0.25 d(-1) (as suggested by the ADM1 for high-rate mesophilic reactors) to 0.13 d(-1) were required to fit the experimental data.

Effects of borrow site preparation and fertilization on natural revegetation

DOT National Transportation Integrated Search

1987-01-01

This study report describes the effects of experimental fertilization and surface conditioning of a gravel borrow site which lacked a topsoil covering. In summary, borrow site revegetation by fireweed may be greatly enhanced by scarifying and fertili...

Effect of microstructure on the static and dynamic behavior of recycled asphalt material

DOT National Transportation Integrated Search

2004-02-01

This report describes the third year's research activities of a project dealing with the micromechanical behavior of asphalt materials. The project involved both theoretical/numerical modeling and experimental studies that were applied to investigate...

Lawrence Livermore National Laboratory two-stage light-gas gun

NASA Astrophysics Data System (ADS)

Mitchell, A. C.; Nellis, W. J.; Trinor, R. J.

1981-10-01

The APS conference on shock waves in condensed matter was held at Menlo Park, Ca, USA on 23 June 1981. The diagnostics and experimental program of a facility used to study condensed matter at high pressures are described.

Effect of microstructure on the static and dynamic behavior of recycled asphalt material

DOT National Transportation Integrated Search

2002-07-01

This report describes the research activities of a project dealing with theoretical/numerical modeling and experimental studies of the micromechanical behavior of recycled asphalt material. The theoretical work employed finite element techniques to d...

Upper Washita River Experimental Watersheds: Physiography Data

USDA-ARS?s Scientific Manuscript database

Physiographic data such as digital elevation models (DEMs), soils, geology, stream channel network characteristics, and channel stability data are essential for understanding the complex hydrologic cycle and chemical transport processes of any given study area. This paper describes physiographic dat...

Modelling of Batch Lactic Acid Fermentation in
the Presence of Anionic Clay

PubMed Central

Jinescu, Cosmin; Aruş, Vasilica Alisa; Nistor, Ileana Denisa

2014-01-01

Summary Batch fermentation of milk inoculated with lactic acid bacteria was conducted in the presence of hydrotalcite-type anionic clay under static and ultrasonic conditions. An experimental study of the effect of fermentation temperature (t=38–43 °C), clay/milk ratio (R=1–7.5 g/L) and ultrasonic field (ν=0 and 35 kHz) on process dynamics was performed. A mathematical model was selected to describe the fermentation process kinetics and its parameters were estimated based on experimental data. A good agreement between the experimental and simulated results was achieved. Consequently, the model can be employed to predict the dynamics of batch lactic acid fermentation with values of process variables in the studied ranges. A statistical analysis of the data based on a 23 factorial experiment was performed in order to express experimental and model-regressed process responses depending on t, R and ν factors. PMID:27904318

Computational study of the interplay between intermolecular interactions and CO2 orientations in type I hydrates.

PubMed

Pérez-Rodríguez, M; Vidal-Vidal, A; Míguez, J M; Blas, F J; Torré, J-P; Piñeiro, M M

2017-01-25

Carbon dioxide (CO 2 ) molecules show a rich orientation landscape when they are enclathrated in type I hydrates. Previous studies have described experimentally their preferential orientations, and some theoretical works have explained, but only partially, these experimental results. In the present paper, we use classical molecular dynamics and electronic density functional theory to advance in the theoretical description of CO 2 orientations within type I hydrates. Our results are fully compatible with those previously reported, both theoretical and experimental, the geometric shape of the cavities in hydrate being, and therefore, the steric constraints, responsible for some (but not all) preferential angles. In addition, our calculations also show that guest-guest interactions in neighbouring cages are a key factor to explain the remaining experimental angles. Besides the implication concerning equation of state hydrate modeling approximations, the conclusion is that these guest-guest interactions should not be neglected, contrary to the usual practice.

Transport relaxation processes in supercritical fluids

NASA Astrophysics Data System (ADS)

Jonas, J.

The technique for solubility measurements of solids in compressed supercritical fluids using NMR and theoretical analysis of experimental data on collision induced scattering were examined. Initial tests for a determination of solid solubilities in supercritical fluids without mixing were previously described and these preparations have continued. Super critical carbon dioxide dissolving naphthalene, for which solubility data is already available (M. McHugh, M.E. Paulaitis, J. Chem. Eng. Data, Vol. 25 (4), 1980) is being studied. This initial testing of the NMR technique for measuring solubilities in a well characterized system should prove very valuable for our later determinations with the proposed mixing probe. Systematic experimental studies of collision induced spectra in several supercritical fluids using both Raman and Rayleigh scattering are continued. The experimental work on SF6 and CH4 was finished and the experimental data testing of the various theoretical models for collision induced scattering is being analyzed.

g-factor measurements of isomeric states in 174W

NASA Astrophysics Data System (ADS)

Rocchini, M.; Nannini, A.; Benzoni, G.; Melon, B.; John, P. R.; Ur, C. A.; Avigo, R.; Bazzacco, D.; Blasi, N.; Bocchi, G.; Bottoni, S.; Bracco, A.; Camera, F.; Ceruti, S.; Crespi, F. C. L.; Georgiev, G.; Giaz, A.; Gottardo, A.; Leoni, S.; Menegazzo, R.; Mengoni, D.; Michelagnoli, C.; Million, B.; Modamio, V.; Morales, A. I.; Napoli, D. R.; Ottanelli, M.; Pellegri, L.; Perego, A.; Valiente-Dobon, J. J.; Wieland, O.

2016-05-01

The experimental setup GAMIPE used for gyro magnetic factor measurements at Laboratori Nazionali di Legnaro and a recent experimental work regarding K-isomers in 174W are described. Aim of the experiment is to study the detailed structure of the isomeric states wave functions, by the measurement of the magnetic dipole moments. This piece of information can provide interesting hints for theoretical models. Preliminary results concerning the population of the isomers of interest and half-lives are presented.

PLANT - An experimental task for the study of human problem solving in process control. [Production Levels and Network Troubleshooting

NASA Technical Reports Server (NTRS)

Morris, N. M.; Rouse, W. B.; Fath, J. L.

1985-01-01

An experimental tool for the investigation of human problem-solving behavior is introduced. Production Levels and Network Troubleshooting (PLANT) is a computer-based process-control task which may be used to provide opportunities for subjects to control a dynamic system and diagnose, repair, and compensate for system failures. The task is described in detail, and experiments which have been conducted using PLANT are briefly discussed.

Experimental and theoretical study of the spread of fluid from a point source on an inclined incontinence bed-pad.

PubMed

Eames, I; Small, I; Frampton, A; Cottenden, A M

2003-01-01

The spread of fluid from a localized source on to a flat fibrous sheet is studied. The sheet is inclined at an angle, alpha, to the horizontal, and the areal flux of the fluid released is Qa. A new experimental study is described where the dimensions of the wetted region are measured as a function of time t, Qa and alpha (>0). The down-slope length, Y, grows according to Y approximately (Qa t)(2/3) (sin alpha)(1/3); for high discharge rates and low angles of inclination, the cross-slope width, X, grows as approximately (Qa t)(1/2), while for low discharge rates or high angles of inclination, the cross-slope transport is dominated by infiltration and X approximately 2(2Ks psi* t)(1/2), where Ks is the saturated permeability and psi* is the characteristic value of capillary pressure. A scaling analysis of the underlying non-linear advection diffusion equation describing the infiltration process confirms many of the salient features of the flow observed. Good agreement is observed between the collapse of the numerical solutions and experimental results. The broader implications of these results for incontinence bed-pad research are briefly discussed.

Effective interactions between soft-repulsive colloids: experiments, theory, and simulations.

PubMed

Mohanty, Priti S; Paloli, Divya; Crassous, Jérôme J; Zaccarelli, Emanuela; Schurtenberger, Peter

2014-03-07

We describe a combined experimental, theoretical, and simulation study of the structural correlations between cross-linked highly monodisperse and swollen Poly(N-isopropylacrylamide) microgel dispersions in the fluid phase in order to obtain the effective pair-interaction potential between the microgels. The density-dependent experimental pair distribution functions g(r)'s are deduced from real space studies using fluorescent confocal microscopy and compared with integral equation theory and molecular dynamics computer simulations. We use a model of Hertzian spheres that is capable to well reproduce the experimental pair distribution functions throughout the fluid phase, having fixed the particle size and the repulsive strength. Theoretically, a monodisperse system is considered whose properties are calculated within the Rogers-Young closure relation, while in the simulations the role of polydispersity is taken into account. We also discuss the various effects arising from the finite resolution of the microscope and from the noise coming from the fast Brownian motion of the particles at low densities, and compare the information content from data taken in 2D and 3D through a comparison with the corresponding simulations. Finally different potential shapes, recently adopted in studies of microgels, are also taken into account to assess which ones could also be used to describe the structure of the microgel fluid.

Hypervelocity impact simulations of Whipple shields

NASA Technical Reports Server (NTRS)

Segletes, Steven B.; Zukas, Jonas A.

1992-01-01

The problem associated with protecting space vehicles from space debris impact is described. Numerical simulation is espoused as a useful complement to experimentation: as a means to help understand and describe the hypervelocity impact phenomena. The capabilities of a PC-based hydrocode, ZeuS, are described, for application to the problem of hypervelocity impact. Finally, results of ZeuS simulations, as applied to the problem of bumper shield impact, are presented and compared with experimental results.

Testing for Questionable Research Practices in a Meta-Analysis: An Example from Experimental Parapsychology.

PubMed

Bierman, Dick J; Spottiswoode, James P; Bijl, Aron

2016-01-01

We describe a method of quantifying the effect of Questionable Research Practices (QRPs) on the results of meta-analyses. As an example we simulated a meta-analysis of a controversial telepathy protocol to assess the extent to which these experimental results could be explained by QRPs. Our simulations used the same numbers of studies and trials as the original meta-analysis and the frequencies with which various QRPs were applied in the simulated experiments were based on surveys of experimental psychologists. Results of both the meta-analysis and simulations were characterized by 4 metrics, two describing the trial and mean experiment hit rates (HR) of around 31%, where 25% is expected by chance, one the correlation between sample-size and hit-rate, and one the complete P-value distribution of the database. A genetic algorithm optimized the parameters describing the QRPs, and the fitness of the simulated meta-analysis was defined as the sum of the squares of Z-scores for the 4 metrics. Assuming no anomalous effect a good fit to the empirical meta-analysis was found only by using QRPs with unrealistic parameter-values. Restricting the parameter space to ranges observed in studies of QRP occurrence, under the untested assumption that parapsychologists use comparable QRPs, the fit to the published Ganzfeld meta-analysis with no anomalous effect was poor. We allowed for a real anomalous effect, be it unidentified QRPs or a paranormal effect, where the HR ranged from 25% (chance) to 31%. With an anomalous HR of 27% the fitness became F = 1.8 (p = 0.47 where F = 0 is a perfect fit). We conclude that the very significant probability cited by the Ganzfeld meta-analysis is likely inflated by QRPs, though results are still significant (p = 0.003) with QRPs. Our study demonstrates that quantitative simulations of QRPs can assess their impact. Since meta-analyses in general might be polluted by QRPs, this method has wide applicability outside the domain of experimental parapsychology.

Characterization of mechanical properties of pericardium tissue using planar biaxial tension and flexural deformation.

PubMed

Murdock, Kyle; Martin, Caitlin; Sun, Wei

2018-01-01

Flexure is an important mode of deformation for native and bioprosthetic heart valves. However, mechanical characterization of bioprosthetic leaflet materials has been done primarily through planar tensile testing. In this study, an integrated experimental and computational cantilever beam bending test was performed to characterize the flexural properties of glutaraldehyde-treated bovine and porcine pericardium of different thicknesses. A strain-invariant based structural constitutive model was used to model the pericardial mechanical behavior quantified through the bending tests of this study and the planar biaxial tests previously performed. The model parameters were optimized through an inverse finite element (FE) procedure in order to describe both sets of experimental data. The optimized material properties were implemented in FE simulations of transcatheter aortic valve (TAV) deformation. It was observed that porcine pericardium TAV leaflets experienced significantly more flexure than bovine when subjected to opening pressurization, and that the flexure may be overestimated using a constitutive model derived from purely planar tensile experimental data. Thus, modeling of a combination of flexural and biaxial tensile testing data may be necessary to more accurately describe the mechanical properties of pericardium, and to computationally investigate bioprosthetic leaflet function and design. Copyright © 2017 Elsevier Ltd. All rights reserved.

Thermal behavior spiral bevel gears. Ph.D. Thesis - Case Western Univ., Aug. 1993

NASA Technical Reports Server (NTRS)

Handschuh, Robert F.

1995-01-01

An experimental and analytical study of the thermal behavior of spiral bevel gears is presented. Experimental data were taken using thermocoupled test hardware and an infrared microscope. Many operational parameters were varied to investigate their effects on the thermal behavior. The data taken were also used to validate the boundary conditions applied to the analytical model. A finite element-based solution sequence was developed. The three-dimensional model was developed based on the manufacturing process for these gears. Contact between the meshing gears was found using tooth contact analysis to describe the location, curvatures, orientations, and surface velocities. This information was then used in a three-dimensional Hertzian contact analysis to predict contact ellipse size and maximum pressure. From these results, an estimate of the heat flux magnitude and the location on the finite element model was made. The finite element model used time-averaged boundary conditions to permit the solution to attain steady state in a computationally efficient manner.Then time- and position-varying boundary conditions were applied to the model to analyze the cyclic heating and cooling due to the gears meshing and transferring heat to the surroundings, respectively. The model was run in this mode until the temperature behavior stabilized. The transient flash temperature on the surface was therefore described. The analysis can be used to predict the overall expected thermal behavior of spiral bevel gears. The experimental and analytical results were compared for this study and also with a limited number of other studies. The experimental and analytical results attained in the current study were basically within 10% of each other for the cases compared. The experimental comparison was for bulk thermocouple locations and data taken with an infrared microscope. The results of a limited number of other studies were compared with those obtained herein and predicted the same basic behavior.

Parametric studies and characterization measurements of x-ray lithography mask membranes

NASA Astrophysics Data System (ADS)

Wells, Gregory M.; Chen, Hector T. H.; Engelstad, Roxann L.; Palmer, Shane R.

1991-08-01

The techniques used in the experimental characterization of thin membranes are considered for their potential use as mask blanks for x-ray lithography. Among the parameters of interest for this evaluation are the film's stress, fracture strength, uniformity of thickness, absorption in the x-ray and visible spectral regions and the modulus and grain structure of the material. The experimental techniques used for measuring these properties are described. The accuracy and applicability of the assumptions used to derive the formulas that relate the experimental measurements to the parameters of interest are considered. Experimental results for silicon carbide and diamond films are provided. Another characteristic needed for an x-ray mask carrier is radiation stability. The number of x-ray exposures expected to be performed in the lifetime of an x-ray mask on a production line is on the order of 107. The dimensional stability requirements placed on the membranes during this period are discussed. Interferometric techniques that provide sufficient sensitivity for these stability measurements are described. A comparison is made between the different techniques that have been developed in term of the information that each technique provides, the accuracy of the various techniques, and the implementation issues that are involved with each technique.

The dual-basin landscape in GFP folding

PubMed Central

Andrews, Benjamin T.; Gosavi, Shachi; Finke, John M.; Onuchic, José N.; Jennings, Patricia A.

2008-01-01

Recent experimental studies suggest that the mature GFP has an unconventional landscape composed of an early folding event with a typical funneled landscape, followed by a very slow search and rearrangement step into the locked, active chromophore-containing structure. As we have shown previously, the substantial difference in time scales is what generates the observed hysteresis in thermodynamic folding. The interconversion between locked and the soft folding structures at intermediate denaturant concentrations is so slow that it is not observed under the typical experimental observation time. Simulations of a coarse-grained model were used to describe the fast folding event as well as identify native-like intermediates on energy landscapes enroute to the fluorescent native fold. Interestingly, these simulations reveal structural features of the slow dynamic transition to chromophore activation. Experimental evidence presented here shows that the trapped, native-like intermediate has structural heterogeneity in residues previously linked to chromophore formation. We propose that the final step of GFP folding is a “locking” mechanism leading to chromophore formation and high stability. The combination of previous experimental work and current simulation work is explained in the context of a dual-basin folding mechanism described above. PMID:18713871

Surgical Technique of Hemi-Face Transplant: A New Model of Training.

PubMed

Cunico, Caroline; Duarte da Silva, Alfredo Benjamim; Brum, Juliana Sperotto; Robes, Rogério Ribeiro; da Silva Freitas, Renato

2016-05-01

Face transplantation from cadaveric donors is an alternative that has been explored as a way to overcome the disadvantages of reconstructive plastic surgery for patients with severe facial deformities, when its approaches are not able to offer good aesthetic and functional results. In this study, the authors describe the surgical technique of face transplantation in swine, investigating the reproducibility of the methods as an experimental model in transplantation. Seven swines were operated upon. After euthanasia, the left hemifacial area was removed and implanted onto the same location on the same animal from which it was removed. The vascular pedicle was based on the facial artery, the caudal auricular artery, and the external jugular vein. The ventral buccal and dorsal buccal branches of the facial nerve and the transverse facial branch of the auricular nerve were taken into the flap. The mean time of the procedure was 4.5 hours. Differences in vascularization were found as the vessel that provides blood supply to auricular region can be the caudal auricular artery, instead of the temporal artery, as described in the literature. Operative difficulty increases if the animal is more obese. The medical student had training in microsurgical procedures to be able to perform the entire procedure. This study describes an experimental model of face transplantation in swine, providing a good model for training of the surgical technique. The method is reproducible in any setting that offers resources in experimental surgery and microsurgery.

A centroid molecular dynamics study of liquid para-hydrogen and ortho-deuterium.

PubMed

Hone, Tyler D; Voth, Gregory A

2004-10-01

Centroid molecular dynamics (CMD) is applied to the study of collective and single-particle dynamics in liquid para-hydrogen at two state points and liquid ortho-deuterium at one state point. The CMD results are compared with the results of classical molecular dynamics, quantum mode coupling theory, a maximum entropy analytic continuation approach, pair-product forward- backward semiclassical dynamics, and available experimental results. The self-diffusion constants are in excellent agreement with the experimental measurements for all systems studied. Furthermore, it is shown that the method is able to adequately describe both the single-particle and collective dynamics of quantum liquids. (c) 2004 American Institute of Physics

The Case Study Method: Guidelines, Practices, and Applications for Vocational Education. Research and Development Series No. 189.

ERIC Educational Resources Information Center

Spirer, Janet E.

In comparison with traditional experimental design, which is concerned with what happened, a case study approach is more appropriate for answering the question of why or how something happened. As an alternative complementary-vocational-education-evaluation approach, the case study attempts to describe and analyze some program in comprehensive…

Acting Like a Physicist: Student Approach Study to Experimental Design

ERIC Educational Resources Information Center

Karelina, Anna; Etkina, Eugenia

2007-01-01

National studies of science education have unanimously concluded that preparing our students for the demands of the 21st century workplace is one of the major goals. This paper describes a study of student activities in introductory college physics labs, which were designed to help students acquire abilities that are valuable in the workplace. In…

Experimental Validation of a Thermoelastic Model for SMA Hybrid Composites

NASA Technical Reports Server (NTRS)

Turner, Travis L.

2001-01-01

This study presents results from experimental validation of a recently developed model for predicting the thermomechanical behavior of shape memory alloy hybrid composite (SMAHC) structures, composite structures with an embedded SMA constituent. The model captures the material nonlinearity of the material system with temperature and is capable of modeling constrained, restrained, or free recovery behavior from experimental measurement of fundamental engineering properties. A brief description of the model and analysis procedures is given, followed by an overview of a parallel effort to fabricate and characterize the material system of SMAHC specimens. Static and dynamic experimental configurations for the SMAHC specimens are described and experimental results for thermal post-buckling and random response are presented. Excellent agreement is achieved between the measured and predicted results, fully validating the theoretical model for constrained recovery behavior of SMAHC structures.

Quasi-experimental Studies in the Fields of Infection Control and Antibiotic Resistance, Ten Years Later: A Systematic Review.

PubMed

Alsaggaf, Rotana; O'Hara, Lyndsay M; Stafford, Kristen A; Leekha, Surbhi; Harris, Anthony D

2018-02-01

OBJECTIVE A systematic review of quasi-experimental studies in the field of infectious diseases was published in 2005. The aim of this study was to assess improvements in the design and reporting of quasi-experiments 10 years after the initial review. We also aimed to report the statistical methods used to analyze quasi-experimental data. DESIGN Systematic review of articles published from January 1, 2013, to December 31, 2014, in 4 major infectious disease journals. METHODS Quasi-experimental studies focused on infection control and antibiotic resistance were identified and classified based on 4 criteria: (1) type of quasi-experimental design used, (2) justification of the use of the design, (3) use of correct nomenclature to describe the design, and (4) statistical methods used. RESULTS Of 2,600 articles, 173 (7%) featured a quasi-experimental design, compared to 73 of 2,320 articles (3%) in the previous review (P<.01). Moreover, 21 articles (12%) utilized a study design with a control group; 6 (3.5%) justified the use of a quasi-experimental design; and 68 (39%) identified their design using the correct nomenclature. In addition, 2-group statistical tests were used in 75 studies (43%); 58 studies (34%) used standard regression analysis; 18 (10%) used segmented regression analysis; 7 (4%) used standard time-series analysis; 5 (3%) used segmented time-series analysis; and 10 (6%) did not utilize statistical methods for comparisons. CONCLUSIONS While some progress occurred over the decade, it is crucial to continue improving the design and reporting of quasi-experimental studies in the fields of infection control and antibiotic resistance to better evaluate the effectiveness of important interventions. Infect Control Hosp Epidemiol 2018;39:170-176.

78 FR 51678 - Market Tests of Experimental Postal Products

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-21

...] Market Tests of Experimental Postal Products AGENCY: Postal Regulatory Commission. ACTION: Proposed rule... tests of experimental products. The proposed rules address the contents of market test filings, describe... Tests I. Introduction The Commission proposes to establish rules governing market tests of experimental...

Studying 3D collisions with smartphones

NASA Astrophysics Data System (ADS)

Pereira, Vanda; Martín-Ramos, Pablo; da Silva, Pedro Pereira; Silva, Manuela Ramos

2017-05-01

This paper describes a conservation of momentum experiment using just smartphones and two beach balls, thus making the experimental study of this movement available to any classroom. For a more thorough analysis of the data, a computer can also be used. Experiments making use of smartphone sensors have been described before, contributing to an improved teaching of classical mechanics. In this experiment, we have made use of two smartphone cameras together with the VidAnalysis free app to track the position of two balls colliding in air during a projectile motion (Fig. 1).

Hypnosis, behavioral theory, and smoking cessation.

PubMed

Covino, N A; Bottari, M

2001-04-01

Although nicotine replacement and other pharmacological treatments head the list of popular interventions for smoking cessation, approaches based on psychology can also assist smokers. Hypnosis, suggestion, and behavior therapies have been offered to patients and studied experimentally for several decades. Although no single psychological approach has been found to be superior to others, psychological interventions contribute significantly to successful treatment outcome in smoking cessation. This article describes common hypnotic and behavioral approaches to smoking cessation and critically reviews some of the findings from clinical and experimental research studies. The authors also offer suggestions regarding treatment and future research.

Modeling and experimental study of resistive switching in vertically aligned carbon nanotubes

NASA Astrophysics Data System (ADS)

Ageev, O. A.; Blinov, Yu F.; Ilina, M. V.; Ilin, O. I.; Smirnov, V. A.

2016-08-01

Model of the resistive switching in vertically aligned carbon nanotube (VA CNT) taking into account the processes of deformation, polarization and piezoelectric charge accumulation have been developed. Origin of hysteresis in VA CNT-based structure is described. Based on modeling results the VACNTs-based structure has been created. The ration resistance of high-resistance to low-resistance states of the VACNTs-based structure amounts 48. The correlation the modeling results with experimental studies is shown. The results can be used in the development nanoelectronics devices based on VA CNTs, including the nonvolatile resistive random-access memory.

Nuclear spectroscopic studies. Progress report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bingham, C.R.; Guidry, M.W.; Riedinger, L.L.

1994-02-18

The Nuclear Physics group at UTK is involved in heavy-ion physics including both nuclear structure and reaction mechanisms. During the last year experimental work has been in 3 broad areas: structure of nuclei at high angular momentum, structure of nuclei far from stability, and ultra-relativistic heavy-ion physics. Results in these areas are described in this document under: properties of high-spin states, study of low-energy levels of nuclei far from stability, and high-energy heavy-ion physics (PHENIX, etc.). Another important component of the work is theoretical interpretation of experimental results (Joint Institute for Heavy Ion Research).

Exact mapping of the 2+1 Dirac oscillator onto the Jaynes-Cummings model: Ion-trap experimental proposal

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bermudez, A.; Martin-Delgado, M. A.; Solano, E.

2007-10-15

We study the dynamics of the 2+1 Dirac oscillator exactly and find spin oscillations due to a Zitterbewegung of purely relativistic origin. We find an exact mapping of this quantum-relativistic system onto a Jaynes-Cummings model, describing the interaction of a two-level atom with a quantized single-mode field. This equivalence allows us to map a series of quantum optical phenomena onto the relativistic oscillator and vice versa. We make a realistic experimental proposal, in reach with current technology, for studying the equivalence of both models using a single trapped ion.

Experimental study of secondary flow in the presence of two jet arrays on the wall of a turbine blade

NASA Astrophysics Data System (ADS)

Seddini, Abdelali

A experimental study of the interaction of the secondary turbine flow with the cooling jets injected at the base of the blades is presented. Subsonic wind tunnel tests were carried on using a gas turbine wheel. The hot wire sensor and the five orifices pressure transducer used in the tests are described. The results allow a satisfactory description of the evolution of the jets in the space between blades and give some indications of the interactions of jets with secondary flows, passing vortices and between themselves.

Experimental selective posterior semicircular canal laser deafferentation.

PubMed

Naguib, Maged B

2005-05-01

In this experimental study, we attempted to perform selective deafferentation of the posterior semicircular canal ampulla of guinea pigs using carbon dioxide laser beam. The results of this study document the efficacy of this procedure in achieving deafferentation of the posterior semicircular canal safely with regards to the other semicircular canals, the otolithic organ and the organ of hearing. Moreover, the procedure is performed with relative ease compared with other procedures previously described for selective deafferentation of the posterior semicircular canal. The clinical application of such a procedure for the treatment of intractable benign paroxysmal positional vertigo in humans is suggested.

Development of an experimental setup for testing the properties of γ/γ' superalloys

NASA Astrophysics Data System (ADS)

Christophe, Siret; Bernard, Viguier; Claude, Salabura Jean; Eric, Andrieu; Sandrine, Lesterlin

2010-07-01

Certification tests on turboshaft engines for helicopters can expose components as high pressure turbine blades to very high temperature during short time periods. To simulate these complex temperature and mechanical stress loadings and to study dimensional and microstructural stability under severe testing conditions, an experimental set-up has been recently developed. In this paper, we first present this new device and describe its performances. Then, the device is used to study the effect of heating procedure on creep results at 1200°C and rafting during primary creep on the single crystal nickel-based superalloy MC2.

HINDERED DIFFUSION OF COAL LIQUIDS

DOE Office of Scientific and Technical Information (OSTI.GOV)

Theodore T. Tsotsis; Muhammad Sahimi; Ian A. Webster

1996-01-01

It was the purpose of the project described here to carry out careful and detailed investigations of petroleum and coal asphaltene transport through model porous systems under a broad range of temperature conditions. The experimental studies were to be coupled with detailed, in-depth statistical and molecular dynamics models intended to provide a fundamental understanding of the overall transport mechanisms and a more accurate concept of the asphaltene structure. The following discussion describes some of our accomplishments.

A Fiber Optic System For The Detection Of Entero-Gastric Reflux

NASA Astrophysics Data System (ADS)

Falciai, R.; Baldini, F.; Conforti, G.; Cosi, F.; Scheggi, A. M...; Bechi, P.

1989-01-01

The study and the development of an optical fiber sensor for entero-gastric and non-acid gastro-esophageal reflux is described. The working principle, based on the spectrophotometric properties of the bile, which constitutes the main part of the reflux, differs from the traditional measurement method, based on pH monitoring. The measuring apparatus is described as well as experimental "in vitro" and preliminary "in vivo" tests are reported.

Chlamydomonas: A Model Green Plant.

ERIC Educational Resources Information Center

Sheffield, E.

1985-01-01

Discusses the instructional potential of Chlamydomonas in providing a basis for a range of experimental investigations to illustrate basic biological phenomena. Describes the use of this algae genus in studies of population growth, photosynthesis, and mating behavior. Procedures for laboratory exercises are included. (ML)

Experimental short-duration techniques. [gas turbine engine tests

NASA Technical Reports Server (NTRS)

Dunn, Michael G.

1986-01-01

Short-duration facilities used for gas turbine studies are described. Data recording techniques; and instruments (thin-film heat flux gages, high-frequency response pressure measurements, total temperature probes, measurement of rotor tip speed, active measurement of tip clearance) are presented.

NASA to launch European cosmic ray experimental satellite

NASA Technical Reports Server (NTRS)

1975-01-01

Europe's first observatory satellite (COS-B) designed for extraterrestrial gamma radiation study and launched on a Delta rocket for the European Space Agency (ESA) by NASA is briefly described. The COS-B's mission objectives are given along with launch operations.

Pilot Study for Definition of Track Component Load Environments

DOT National Transportation Integrated Search

1981-02-01

This report describes the results of an experimental and analytical effort to define the vehicle induced load environment in an at-grade, concrete tie/ballast transit track structure. The experiment was performed on the UMTA transit track oval at the...

Microwave scanning beam approach and landing system phased array antenna volume I

DOT National Transportation Integrated Search

1973-02-01

The use of phased arrays for the proposed landing system (MLS) is discussed. Studies relating to ground reflections, near field focusing, and phased-array errors are presented. Two experimental antennas which were fabricated and tested are described....

Microwave scanning beam approach and landing system phased array antenna : volume II

DOT National Transportation Integrated Search

1973-02-01

The use of phased arrays for the proposed landing system (MLS) is discussed. Studies relating to ground reflections, near field focusing, and phased-array errors are presented. Two experimental antennas which were fabricated and tested are described....

Influence of a Binder Layer on the Response Time of Pressure-Sensitive Coatings

NASA Astrophysics Data System (ADS)

Zharkova, G. M.; Khachaturyan, V. M.; Malov, A. N.; Lopatkina, A. A.

2002-07-01

The present work describes an experimental study of pressure-sensitive luminescent coatings containing phosphors prepared on different substrates. Data are presented concerning measurements of luminescence intensity and luminescence decay kinetics at different pressures and temperatures.

Theory overview of tree-level B decays

NASA Astrophysics Data System (ADS)

De Fazio, F.

2017-07-01

I describe the theoretical progress in the study of semileptonic tree-level B decays, and its interplay with recent experimental results. In particular, I focus on two anomalies: the ratios $R(D^{(*)})=\\displaystyle\\frac{{\\cal B}(B \\to D^{(*)} \\tau \\bar \

The Shock Compression Laboratory at Harvard: A New Facility for Planetary Impact Processes

NASA Technical Reports Server (NTRS)

Stewart, S. T.

2004-01-01

The Shock Compression Laboratory in the Department of Earth and Planetary Sciences at Harvard is a new facility for the study of impact and collisional phenomena. The following describes the experimental capabilities of the laboratory.

On previous and present investigations of resonance gamma-ray interaction with nuclei at the Institute of Theoretical and Experimental Physics (ITEP, Moscow)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Davydov, A. V.

A brief survey of theoretical and experimental work that is devoted to studying the resonance absorption and scattering of gamma rays by nuclei and which was initiated at the Institute of Theoretical and Experimental Physics (ITEP, Moscow) in the 1950s and has been continued to date is given. Investigations of various versions of interaction in beta decay, magnetic-field-perturbed angular distributions of resonantly scattered gamma rays, the problem of the Moessbauer gamma resonance of long-lived isomeric states of nuclei, and the resonance scattering of annihilation photons by nuclei are described.

Theoretical and experimental studies of error in square-law detector circuits

NASA Technical Reports Server (NTRS)

Stanley, W. D.; Hearn, C. P.; Williams, J. B.

1984-01-01

Square law detector circuits to determine errors from the ideal input/output characteristic function were investigated. The nonlinear circuit response is analyzed by a power series expansion containing terms through the fourth degree, from which the significant deviation from square law can be predicted. Both fixed bias current and flexible bias current configurations are considered. The latter case corresponds with the situation where the mean current can change with the application of a signal. Experimental investigations of the circuit arrangements are described. Agreement between the analytical models and the experimental results are established. Factors which contribute to differences under certain conditions are outlined.

Experimental study on natural circulation precooling of cryogenic pump system with gas phase inlet reflux configuration

NASA Astrophysics Data System (ADS)

Chen, G. B.; Zhong, Y. K.; Zheng, X. L.; Li, Q. F.; Xie, X. M.; Gan, Z. H.; Huang, Y. H.; Tang, K.; Kong, B.; Qiu, L. M.

2003-12-01

A novel gas-phase inlet configuration in the natural circulation system instead of the liquid-phase inlet is introduced to cool down a cryogenic pump system from room temperature to cryogenic temperatures, effectively. The experimental apparatus is illustrated and test process is described. Heat transfer and pressure drop data during the cool-down process are recorded and portrayed. By contrast with liquid-phase inlet configuration, experimental results demonstrate that the natural circulation with the gas-phase inlet configuration is an easier and more controllable way to cool down the pump system and maintain it at cryogenic temperatures.

Design and Implementation of an Experimental Cataloging Advisor--Mapper.

ERIC Educational Resources Information Center

Ercegovac, Zorana; Borko, Harold

1992-01-01

Describes the design of an experimental computer-aided cataloging advisor, Mapper, that was developed to help novice users with the descriptive cataloging of single-sheet maps from U.S. publishers. The human-computer interface is considered, the use of HyperCard is discussed, the knowledge base is explained, and assistance screens are described.…

The Use of Techniques of Sensory Evaluation as a Framework for Teaching Experimental Methods.

ERIC Educational Resources Information Center

Bennett, R.; Hamilton, M.

1981-01-01

Describes sensory assessment techniques and conditions for their satisfactory performance, including how they can provide open-ended exercises and advantages as relatively inexpensive and simple methods of teaching experimentation. Experiments described focus on diffusion of salt into potatoes after being cooked in boiled salted water. (Author/JN)

Procedures for cryogenic X-ray ptychographic imaging of biological samples

DOE Office of Scientific and Technical Information (OSTI.GOV)

Yusuf, M.; Zhang, F.; Chen, B.

Biological sample-preparation procedures have been developed for imaging human chromosomes under cryogenic conditions. A new experimental setup, developed for imaging frozen samples using beamline I13 at Diamond Light Source, is described. This paper describes the equipment and experimental procedures as well as the authors' first ptychographic reconstructions using X-rays.

Cultures of Experimental Practice--An Approach in a Museum.

ERIC Educational Resources Information Center

Heering, Peter; Muller, Falk

2002-01-01

Describes generations and experiences of an exhibition presented in Spring 1998 at the Oldenburg Museum of Natural History and Pre-History. Discusses the thematic leitmotiv of this exhibition which was to present experiments from the history of physics as a cultural activity. Describes how reconstructions of historical experimental set-ups were…

Procedures for cryogenic X-ray ptychographic imaging of biological samples

DOE PAGES

Yusuf, M.; Zhang, F.; Chen, B.; ...

2017-01-12

Biological sample-preparation procedures have been developed for imaging human chromosomes under cryogenic conditions. A new experimental setup, developed for imaging frozen samples using beamline I13 at Diamond Light Source, is described. This paper describes the equipment and experimental procedures as well as the authors' first ptychographic reconstructions using X-rays.

Teaching Science Problem Solving: An Overview of Experimental Work.

ERIC Educational Resources Information Center

Taconis, R.; Ferguson-Hessler, M. G. M.; Broekkamp, H.

2001-01-01

Performs analysis on a number of articles published between 1985 and 1995 describing experimental research into the effectiveness of a wide variety of teaching strategies for science problem solving. Identifies 22 articles describing 40 experiments that met standards for meta-analysis. Indicates that few of the independent variables were found to…

Alcohol and the developing fetus--a review.

PubMed

Chaudhuri, J D

2000-01-01

Fetal alcohol syndrome (FAS) is a collection of signs and symptoms seen in some children exposed to alcohol in the prenatal period. It is characterized mainly by physical and mental retardation, craniofacial anomalies and minor joint abnormalities. However, with the increasing incidence of FAS, there is a great variation in the clinical features of FAS. This article describes in detail these clinical features. Due to ethical reasons it is not possible to perform experiments on pregnant women. Hence to study the effects of alcohol, various animal and avian experimental models have been chosen. The various experimental findings and human correlation are described. The exact mechanism by which alcohol induces its teratogenic effects is not known. The possible mechanisms are discussed. Measures to prevent the occurrence of FAS have been suggested.

Dynamic conductivity and partial ionization in dense fluid hydrogen

NASA Astrophysics Data System (ADS)

Zaghoo, Mohamed

2018-04-01

A theoretical description for optical conduction experiments in dense fluid hydrogen is presented. Different quantum statistical approaches are used to describe the mechanism of electronic transport in hydrogen's high-temperature dense phase. We show that at the onset of the metallic transition, optical conduction could be described by a strong rise in atomic polarizability, due to increased ionization, whereas in the highly degenerate limit, the Ziman weak scattering model better accounts for the observed saturation of reflectance. The inclusion of effects of partial ionization in the highly degenerate region provides great agreement with experimental results. Hydrogen's fluid metallic state is revealed to be a partially ionized free-electron plasma. Our results provide some of the first theoretical transport models that are experimentally benchmarked, as well as an important guide for future studies.

Modelling and simulation of a moving interface problem: freeze drying of black tea extract

NASA Astrophysics Data System (ADS)

Aydin, Ebubekir Sıddık; Yucel, Ozgun; Sadikoglu, Hasan

2017-06-01

The moving interface separates the material that is subjected to the freeze drying process as dried and frozen. Therefore, the accurate modeling the moving interface reduces the process time and energy consumption by improving the heat and mass transfer predictions during the process. To describe the dynamic behavior of the drying stages of the freeze-drying, a case study of brewed black tea extract in storage trays including moving interface was modeled that the heat and mass transfer equations were solved using orthogonal collocation method based on Jacobian polynomial approximation. Transport parameters and physical properties describing the freeze drying of black tea extract were evaluated by fitting the experimental data using Levenberg-Marquardt algorithm. Experimental results showed good agreement with the theoretical predictions.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Andronov, V.A.; Zhidov, I.G.; Meskov, E.E.

This report describes an extensive program of investigations conducted at Arzamas-16 in Russia over the past several decades. The focus of the work is on material interface instability and the mixing of two materials. Part 1 of the report discusses analytical and computational studies of hydrodynamic instabilities and turbulent mixing. The EGAK codes are described and results are illustrated for several types of unstable flow. Semiempirical turbulence transport equations are derived for the mixing of two materials, and their capabilities are illustrated for several examples. Part 2 discusses the experimental studies that have been performed to investigate instabilities and turbulentmore » mixing. Shock-tube and jelly techniques are described in considerable detail. Results are presented for many circumstances and configurations.« less

Optical workstation with concurrent, independent multiphoton imaging and experimental laser microbeam capabilities

PubMed Central

Wokosin, David L.; Squirrell, Jayne M.; Eliceiri, Kevin W.; White, John G.

2008-01-01

Experimental laser microbeam techniques have become established tools for studying living specimens. A steerable, focused laser beam may be used for a variety of experimental manipulations such as laser microsurgery, optical trapping, localized photolysis of caged bioactive probes, and patterned photobleaching. Typically, purpose-designed experimental systems have been constructed for each of these applications. In order to assess the consequences of such experimental optical interventions, long-term, microscopic observation of the specimen is often required. Multiphoton excitation, because of its ability to obtain high-contrast images from deep within a specimen with minimal phototoxic effects, is a preferred technique for in vivo imaging. An optical workstation is described that combines the functionality of an experimental optical microbeam apparatus with a sensitive multiphoton imaging system designed for use with living specimens. Design considerations are discussed and examples of ongoing biological applications are presented. The integrated optical workstation concept offers advantages in terms of flexibility and versatility relative to systems implemented with separate imaging and experimental components. PMID:18607511

Optical workstation with concurrent, independent multiphoton imaging and experimental laser microbeam capabilities

NASA Astrophysics Data System (ADS)

Wokosin, David L.; Squirrell, Jayne M.; Eliceiri, Kevin W.; White, John G.

2003-01-01

Experimental laser microbeam techniques have become established tools for studying living specimens. A steerable, focused laser beam may be used for a variety of experimental manipulations such as laser microsurgery, optical trapping, localized photolysis of caged bioactive probes, and patterned photobleaching. Typically, purpose-designed experimental systems have been constructed for each of these applications. In order to assess the consequences of such experimental optical interventions, long-term, microscopic observation of the specimen is often required. Multiphoton excitation, because of its ability to obtain high-contrast images from deep within a specimen with minimal phototoxic effects, is a preferred technique for in vivo imaging. An optical workstation is described that combines the functionality of an experimental optical microbeam apparatus with a sensitive multiphoton imaging system designed for use with living specimens. Design considerations are discussed and examples of ongoing biological applications are presented. The integrated optical workstation concept offers advantages in terms of flexibility and versatility relative to systems implemented with separate imaging and experimental components.

Optical Studies of Semiconductor Heterostructures: Measurements of Tunneling Times, and Studies of Strained Superlattices.

NASA Astrophysics Data System (ADS)

Jackson, Michael Kevin

1991-05-01

This thesis describes experimental optical studies of semiconductor heterostructures. The topic is introduced in Chapter 1. In Chapter 2 we describe measurements of tunneling escape times for carriers photoexcited in the quantum well of an undoped GaAs/AlAs/GaAs/AlAs/GaAs double -barrier heterostructure. The first experimental measurements of the tunneling escape times for both electrons and heavy holes were made using the two-beam technique of photoluminescence excitation correlation spectroscopy (PECS). Heavy holes were observed to escape much more rapidly than expected from a simple one-band calculation of the heavy-hold tunneling escape time. This can be explained by considering a four -band model for holes. Calculations indicate that mixing of the quantum well heavy- and light-hole levels, due to dispersion in the plane of the quantum well, can lead to significantly faster heavy hole escape at the experimental carrier densities and temperatures. Chapter 3 describes a study of the effect of indirect (X-point) levels in the AlAs barriers on the tunneling escape of electrons in undoped double-barrier heterostructures. The X-point levels affect the escape of photoexcited electrons in devices where the energy of the electron state confined in the GaAs quantum well is nearly equal to, or higher than, that of the X-point levels in the AlAs barriers. In Chapter 4, we present time-resolved photoluminescence and photocurrent studies of electrically biased double -barrier heterostructures. Studies of the photoluminescence indicate that transport of photoexcited carriers from the electrodes into the quantum well occurs. The PECS technique has been extended to a study of photocurrents in these devices; results indicate that this technique may be useful for the study of devices that cannot be studied with photoluminescence. Chapter 5 describes a study of the accomodation of lattice mismatch in CdTe/ZnTe strained layer superlattices. Using resonance Raman scattering, the energies of the ZnTe-like phonons were determined in a series of superlattices. The ZnTe-like phonon energies decrease with increasing average CdTe content, indicative of the increasing strain of the ZnTe layers, and in agreement with calculations assuming a free-standing superlattice.

Brownian Motion at Lipid Membranes: A Comparison of Hydrodynamic Models Describing and Experiments Quantifying Diffusion within Lipid Bilayers.

PubMed

Block, Stephan

2018-05-22

The capability of lipid bilayers to exhibit fluid-phase behavior is a fascinating property, which enables, for example, membrane-associated components, such as lipids (domains) and transmembrane proteins, to diffuse within the membrane. These diffusion processes are of paramount importance for cells, as they are for example involved in cell signaling processes or the recycling of membrane components, but also for recently developed analytical approaches, which use differences in the mobility for certain analytical purposes, such as in-membrane purification of membrane proteins or the analysis of multivalent interactions. Here, models describing the Brownian motion of membrane inclusions (lipids, peptides, proteins, and complexes thereof) in model bilayers (giant unilamellar vesicles, black lipid membranes, supported lipid bilayers) are summarized and model predictions are compared with the available experimental data, thereby allowing for evaluating the validity of the introduced models. It will be shown that models describing the diffusion in freestanding (Saffman-Delbrück and Hughes-Pailthorpe-White model) and supported bilayers (the Evans-Sackmann model) are well supported by experiments, though only few experimental studies have been published so far for the latter case, calling for additional tests to reach the same level of experimental confirmation that is currently available for the case of freestanding bilayers.

Voltage-Clamp Studies on Uterine Smooth Muscle

PubMed Central

Anderson, Nels C.

1969-01-01

These studies have developed and tested an experimental approach to the study of membrane ionic conductance mechanisms in strips of uterine smooth muscle. The experimental and theoretical basis for applying the double sucrose-gap technique is described along with the limitations of this system. Nonpropagating membrane action potentials were produced in response to depolarizing current pulses under current-clamp conditions. The stepwise change of membrane potential under voltage-clamp conditions resulted in a family of ionic currents with voltage- and time-dependent characteristics. In sodium-free solution the peak transient current decreased and its equilibrium potential shifted along the voltage axis toward a more negative internal potential. These studies indicate a sodium-dependent, regenerative excitation mechanism. PMID:5796366

The Design of Effective Case Study-Related Learning Strategies Training.

ERIC Educational Resources Information Center

Nuttall, Alice E.

The development of case study training materials for an experimental research strategy is described, and the effects of such training are discussed. The theoretical foundation for learning strategies training was a social-cognitive/expectancy value model of college learning and teaching. In a posttest-only 2-group design, 54 students in an…

Ethnic Heritage Studies: German-American Profiles and Contributions--Major Figures. Experimental Unit.

ERIC Educational Resources Information Center

Allen, Talbott

This teaching guide focuses on several prominent German-Americans and their contributions to American life, and provides some insights into German culture. It is part of the Louisville Area Ethnic Heritage Studies Project described in ED 150 043. The project materials are designed to foster communication across intercultural/ethnic lines. The…

Development and Use of Curricular Adaptations for Students Receiving Special Education Services

ERIC Educational Resources Information Center

Kurth, Jennifer A.; Keegan, Lissa

2014-01-01

This study is a quasi-experimental descriptive design, with existing educator-made adaptations evaluated. The goals of this study were to (a) describe how educators develop adaptations and (b) evaluate the effectiveness of educator-made adaptations in facilitating the learning of students with disabilities. Findings suggest that (a) most…

Ethnic Heritage Studies: Southern European Foods. Experimental Unit.

ERIC Educational Resources Information Center

Freepartner, Susan

This teaching guide focuses on the Southern European food heritage. It is part of the Louisville Area Ethnic Heritage Studies Project described in ED 150 043. The project materials are designed to foster communication across intercultural/ethnic lines. The objective of this unit is to gain familiarity with and appreciate foods from Spain, France,…

Violent Florida Weather, Science (Experimental): 5343.05.

ERIC Educational Resources Information Center

Espy, J. A., Jr.

This is a basic weather course describing Florida's weather and is designed to give the student the opportunity to study the phenomena which cause the more destructive disturbances in the atmosphere. The study includes the detection, growth, effects and possible alternation of storms. It is suggested that a student enrolled in this course would…

An Inexpensive High Pressure Optical Absorption Cell for IR-VIS-UV Studies.

ERIC Educational Resources Information Center

Rodgers, V. E.; Angell, C. A.

1983-01-01

Describes an optical cell, suitable for high-pressure studies between at least -130 and +150 degrees Celsius, which may be assembled for about $50. Discusses experimental demonstration of principles involved when using the apparatus, including effects of pressure on coordination of ions in solution and on reaction rates in solution. (JN)

An Experience-Centered Curriculum: Exercises in Perception, Communication and Action. Educational Studies and Documents No. 17.

ERIC Educational Resources Information Center

Wolsk, David

This study describes a Unesco-sponsored experimental project in the United Nations Associated Schools designed to develop a new approach to education for international understanding. The class, school, and community provide the settings for activities based on the pupils' own behaviors and experiences. Experiments, demonstrations, critical…

Learning for Understanding: A Faculty-Driven Paradigm Shift in Learning, Imaginative Teaching, and Creative Assessment

ERIC Educational Resources Information Center

Diaz-Lefebvre, Rene

2006-01-01

This article describes an experimental pilot study begun in 1994 in the Glendale Community College (Glendale, Arizona) psychology department. The faculty-driven idea incorporated Howard Gardner's multiple intelligences theory (MI) into a new paradigm--one where creative forms of learning resulted in real understanding. The pilot study, Multiple…

Avoiding Procrastination through Time Management: An Experimental Intervention Study

ERIC Educational Resources Information Center

Häfner, Alexander; Oberst, Verena; Stock, Armin

2014-01-01

The purpose of this study was to examine the effects of a short-term time management intervention on procrastination. Procrastination is a serious issue for many students and associated with different negative consequences, such as anxiety or low grades. As procrastination is described as a self-regulatory failure, a training programme focussing…

Developmental Changes in Constructive Memory Abilities.

ERIC Educational Resources Information Center

Paris, Scott G.

This paper describes three studies designed to determine whether there are age-related differences in children's memory for implicit and explicit information in prose. In the first study, six experimental paragraphs were read individually to a total of 60 children in grades K-5. Each child was then asked four verbatim recall questions (specific…

A gastroplasty for short esophagus and reflux esophagitis: experimental and clinical studies.

PubMed Central

Demos, N J; Smith, N; Williams, D

1975-01-01

A safe, simple, effective gastroplasty for short esophagus with reflux esophagitis is described. It has been evaluated in dogs for up to three years with flexible fiberesophagoscopy, esophagrams and intraluminal pressure studies. Successful clinical experience has been encouraging. Images Fig. 2. Fig. 3. Fig. 5. Fig. 6. Fig. 7. PMID:1089392

Promoting the Development of Mentor Teachers: Theory and Research Programs Using Guided Reflection.

ERIC Educational Resources Information Center

Reiman, Alan J.; Thies-Sprinthall, Lois

1993-01-01

Describes theory and a research program that uses guided reflection to promote the development of mentor teachers. Significant findings from a quasi-experimental study and a replication study are presented. The paper can assist teacher educators, policymakers, and school personnel who are searching for a teacher induction model. (GLR)

Knotworking and the Visibilization of Learning in Building Design

ERIC Educational Resources Information Center

Kerosuo, Hannele; Mäki, Tarja; Korpela, Jenni

2015-01-01

Purpose: This paper aims to study the visibilization of learning in the context of developing a new collaborative practice, knotworking, in building design. The case under study describes the process of learning from the initiation of knotworking to its experimentation. The implementation of new building information modeling tools acted as an…

Coding System for the First Grade Reading Group Study.

ERIC Educational Resources Information Center

Brophy, Jere; And Others

The First-Grade Reading Group Study is an experimental examination of teaching behaviors and their effects in first-grade reading groups. The specific teaching behaviors of interest are defined by a model for small group instruction which describes organization and management of the class, and ways of responding to children's answers that are…

Photothermal technique in cell microscopy studies

NASA Astrophysics Data System (ADS)

Lapotko, Dmitry; Chebot'ko, Igor; Kutchinsky, Georgy; Cherenkevitch, Sergey

1995-01-01

Photothermal (PT) method is applied for a cell imaging and quantitative studies. The techniques for cell monitoring, imaging and cell viability test are developed. The method and experimental set up for optical and PT-image acquisition and analysis is described. Dual- pulsed laser set up combined with phase contrast illumination of a sample provides visualization of temperature field or absorption structure of a sample with spatial resolution 0.5 micrometers . The experimental optics, hardware and software are designed using the modular principle, so the whole set up can be adjusted for various experiments: PT-response monitoring or photothermal spectroscopy studies. Sensitivity of PT-method provides the imaging of the structural elements of live (non-stained) white blood cells. The results of experiments with normal and subnormal blood cells (red blood cells, lymphocytes, neutrophyles and lymphoblasts) are reported. Obtained PT-images are different from optical analogs and deliver additional information about cell structure. The quantitative analysis of images was used for cell population comparative diagnostic. The viability test for red blood cell differentiation is described. During the study of neutrophyles in norma and sarcoidosis disease the differences in PT-images of cells were found.

A comparison of experimental and theoretical results for rotordynamic coefficients of four annular gas seals

NASA Technical Reports Server (NTRS)

Childs, D. W.; Nelson, C. C.; Elrod, D.; Nicks, C.

1985-01-01

The test facility and initial test program developed to experimentally measure the fluid forces induced by annular gas seals is described. A comparison of theoretically predicted and experimentally obtained data for smooth and honeycomb seals is provided. And a comparison of experimental data from the tests of three smooth-rotor/smooth-stator seals is provided. The leakage of the working fluid through the seal, the pressure gradient along the seal length, entrance pressure-loss data, and rotordynamic coefficients provide a basis for comparison. A short discussion on seal theory is included, and various rotordynamic coefficient identification schemes are described.

Experimental aeroelasticity history, status and future in brief

NASA Technical Reports Server (NTRS)

Ricketts, Rodney H.

1990-01-01

NASA conducts wind tunnel experiments to determine and understand the aeroelastic characteristics of new and advanced flight vehicles, including fixed-wing, rotary-wing and space-launch configurations. Review and assessments are made of the state-of-the-art in experimental aeroelasticity regarding available facilities, measurement techniques, and other means and devices useful in testing. In addition, some past experimental programs are described which assisted in the development of new technology, validated new analysis codes, or provided needed information for clearing flight envelopes of unwanted aeroelastic response. Finally, needs and requirements for advances and improvements in testing capabilities for future experimental research and development programs are described.

Modeling the Structure of Helical Assemblies with Experimental Constraints in Rosetta.

PubMed

André, Ingemar

2018-01-01

Determining high-resolution structures of proteins with helical symmetry can be challenging due to limitations in experimental data. In such instances, structure-based protein simulations driven by experimental data can provide a valuable approach for building models of helical assemblies. This chapter describes how the Rosetta macromolecular package can be used to model homomeric protein assemblies with helical symmetry in a range of modeling scenarios including energy refinement, symmetrical docking, comparative modeling, and de novo structure prediction. Data-guided structure modeling of helical assemblies with experimental information from electron density, X-ray fiber diffraction, solid-state NMR, and chemical cross-linking mass spectrometry is also described.

Direct current electrical potential measurement of the growth of small cracks

NASA Technical Reports Server (NTRS)

Gangloff, Richard P.; Slavik, Donald C.; Piascik, Robert S.; Van Stone, Robert H.

1992-01-01

The analytical and experimental aspects of the direct-current electrical potential difference (dcEPD) method for continuous monitoring of the growth kinetics of short (50 to 500 microns) fatigue cracks are reviewed, and successful applications of the deEPD method to study fatigue crack propagation in a variety of metallic alloys exposed to various environments are described. Particular attention is given to the principle of the dcEPD method, the analytical electrical potential calibration relationships, and the experimental procedures and equipment.

Thermal energy storage flight experiments

NASA Technical Reports Server (NTRS)

Namkoong, D.

1989-01-01

Consideration is given to the development of an experimental program to study heat transfer, energy storage, fluid movement, and void location under microgravity. Plans for experimental flight packages containing Thermal Energy Storage (TES) material applicable for advanced solar heat receivers are discussed. Candidate materials for TES include fluoride salts, salt eutectics, silicides, and metals. The development of a three-dimensional computer program to describe TES material behavior undergoing melting and freezing under microgravity is also discussed. The TES experiment concept and plans for ground and flight tests are outlined.

Energy anisotropy as a function of the direction of spin magnetization for a doublet system

NASA Astrophysics Data System (ADS)

Cherry, Peter J.; Malkin, Vladimir G.; Malkina, Olga L.; Asher, James R.

2016-11-01

This manuscript describes new phenomena that currently are not taken into account in both experimental EPR spectra interpretations and quantum chemical calculations of EPR parameters. This article presents an argument, with evidence, against the common belief that in the absence of an external magnetic field the total energy of a doublet system is independent of the spin orientation. Consequences of this phenomenon for interpretation of EPR experimental studies as well as for quantum chemical calculations of EPR parameters are discussed.

Production of a large, quiescent, magnetized plasma

NASA Technical Reports Server (NTRS)

Landt, D. L.; Ajmera, R. C.

1976-01-01

An experimental device is described which produces a large homogeneous quiescent magnetized plasma. In this device, the plasma is created in an evacuated brass cylinder by ionizing collisions between electrons emitted from a large-diameter electron gun and argon atoms in the chamber. Typical experimentally measured values of the electron temperature and density are presented which were obtained with a glass-insulated planar Langmuir probe. It is noted that the present device facilitates the study of phenomena such as waves and diffusion in magnetized plasmas.

Dark soliton fiber lasers.

PubMed

Tang, Dingyuan; Guo, Jun; Song, Yufeng; Zhang, Han; Zhao, Luming; Shen, Deyuan

2014-08-11

Dark soliton formation and soliton dynamics in all-normal dispersion cavity fiber ring lasers without an anti-saturable absorber in cavity is studied both theoretically and numerically. It is shown that under suitable conditions the dark solitons formed could be described by the nonlinear Schrödinger equation. The dark soliton formation in an all-normal-dispersion cavity erbium-doped fiber ring laser without an anti-saturable absorber in cavity is first experimentally demonstrated. Individual dark solitons are experimentally identified. Excellent agreement between theory and experiment is observed.

Experimental study on direct adaptive control of a PUMA 560 industrial robot

NASA Technical Reports Server (NTRS)

Seraji, H.; Lee, T.; Delpech, M.

1990-01-01

The implementation and experimental validation of a direct adaptive control scheme on a PUMA 560 industrial robot is discussed. The design theory for direct adaptive control of manipulators is outlined and the test facility and software are described. Results are presented from the experiments on the simultaneous control of all of the six joint angles and control of the end-effector position and orientation of the robot. Also, the possible applications of the direct adaptive control scheme are considered.

Pressure losses and heat transfer in non-circular channels with hydraulically smooth walls

NASA Technical Reports Server (NTRS)

Malak, J.

1982-01-01

The influence of channel geometry on pressure losses and heat transfer in noncircular channels with hydraulically smooth walls was studied. As a basic assumption for the description of this influence, integral geometrical criteria, selected according to experimental experience, were introduced. Using these geometrical criteria, a large set of experimental data for pressure losses and heat transfer in circular and annular channels with longitudinal fins was evaluated. In this way it as empirically proved that the criteria described channel geometry fairly well.

Detection of fuze defects by image-processing methods

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chung, M.J.

1988-03-01

This paper describes experimental studies of the detection of mechanical defects by the application of computer-processing methods to real-time radiographic images of fuze assemblies. The experimental results confirm that a new algorithm developed at Materials Research Laboratory has potential for the automatic inspection of these assemblies and of others that contain discrete components. The algorithm was applied to images that contain a range of grey levels and has been found to be tolerant to image variations encountered under simulated production conditions.

Characterization of hypersonic roughness-induced boundary-layer transition

NASA Astrophysics Data System (ADS)

Tirtey, S. C.; Chazot, O.; Walpot, L.

2011-02-01

The flow-field structure in the vicinity and in the wake of an isolated 3D roughness element has been studied. Different experimental techniques have been coupled and supported by CFD simulation for a good understanding of the flow-field topology. The results have shown strong flow-field similarities for different roughness elements. A model describing the flow structure and interaction mechanisms has been proposed. This model is in good agreement with experimental and CFD results as well as the literature.

Computer-based visual communication in aphasia.

PubMed

Steele, R D; Weinrich, M; Wertz, R T; Kleczewska, M K; Carlson, G S

1989-01-01

The authors describe their recently developed Computer-aided VIsual Communication (C-VIC) system, and report results of single-subject experimental designs probing its use with five chronic, severely impaired aphasic individuals. Studies replicate earlier results obtained with a non-computerized system, demonstrate patient competence with the computer implementation, extend the system's utility, and identify promising areas of application. Results of the single-subject experimental designs clarify patients' learning, generalization, and retention patterns, and highlight areas of performance difficulties. Future directions for the project are indicated.

[Disturbances in time perception in relation to changes in experiencing music in experimental psychosis].

PubMed

Weber, K

1977-01-01

Music is a structure ('Gestalt') in time. The recognition of disturbances of the perception of music enhances the knowledge of disorders of perception of time. Disturbances of perception of music and time in experimental psychoses (psilocybine) are discussed in relation to the studies by Piaget on the development of the notion of time in childhood. The results allow a new interpretation of the disturbances of the perception of time in diencephalic disorders as described in the literature.

Results of design studies and wind tunnel tests of an advanced high lift system for an Energy Efficient Transport

NASA Technical Reports Server (NTRS)

Oliver, W. R.

1980-01-01

The development of an advanced technology high lift system for an energy efficient transport incorporating a high aspect ratio supercritical wing is described. This development is based on the results of trade studies to select the high lift system, analysis techniques utilized to design the high lift system, and results of a wind tunnel test program. The program included the first experimental low speed, high Reynolds number wind tunnel test for this class of aircraft. The experimental results include the effects on low speed aerodynamic characteristics of various leading and trailing edge devices, nacelles and pylons, aileron, spoilers, and Mach and Reynolds numbers. Results are discussed and compared with the experimental data and the various aerodynamic characteristics are estimated.

Linear free-energy relationships and the density functional theory: an analog of the hammett equation.

PubMed

Simón-Manso, Yamil

2005-03-10

Density functional theory has been applied to describe electronic substituent effects, especially in the pursuit of linear relationships similar to those observed from physical organic chemistry experiments. In particular, analogues for the Hammett equation parameters (sigma, rho) have been developed. Theoretical calculations were performed on several series of organic molecules in order to validate our model and for comparison with experimental results. The trends obtained by Hammett-like relations predicted by the model were found to be in qualitative agreement with the experimental data. The results obtained in this study suggest the applicability of similar correlation analysis based on theoretical methodologies that do not make use of empirical fits to experimental data can be useful in the study of substituent effects in organic chemistry.

Neuroprotective properties of curcumin in toxin-base animal models of Parkinson's disease: a systematic experiment literatures review.

PubMed

Wang, Xin-Shi; Zhang, Zeng-Rui; Zhang, Man-Man; Sun, Miao-Xuan; Wang, Wen-Wen; Xie, Cheng-Long

2017-08-17

Curcumin (diferuloylmethane), a polyphenol extracted from the plant Curcuma longa, is widely used in Southeast Asia, China and India in food preparation and for medicinal purposes. Meanwhile, the neuroprotective actions of curcumin have been documented for experimental therapy in Parkinson's disease (PD). In this study, we used a systematic review to comprehensively assess the efficacy of curcumin in experimental PD. Using electronic and manual search for the literatures, we identified studies describing the efficacy of curcumin in animal models of PD. We identified 13 studies with a total of 298 animals describing the efficacy of curcumin in animal models of PD. The methodological quality of all preclinical trials is ranged from 2 to 5. The majority of the experiment studies demonstrated that curcumin was more significantly neuroprotection effective than control groups for treating PD. Among them, five studies indicated that curcumin had an anti-inflammatory effect in the PD animal models (p < 0.05). Meanwhile, four studies showed the antioxidant capability of curcumin, by which it protected substantia nigra neurons and improved striatal dopamine levels. Furthermore, two studies in this review displayed that curcumin treatment was also effective in reducing neuronal apoptosis and improving functional outcome in animal models of PD. Most of the preclinical studies demonstrated the positive findings while one study reported that curcumin had no beneficial effects against Mn-induced disruption of hippocampal metal and neurotransmitter homeostasis. The results demonstrated a marked efficacy of curcumin in experimental model of PD, suggesting curcumin probably a candidate neuroprotective drug for human PD patients.

Investigation of the Mesostructure of Transition-Metal Monogermanides Synthesized under Pressure

NASA Astrophysics Data System (ADS)

Safiulina, I. A.; Altynbaev, E. V.; Iashina, E. G.; Heinemann, A.; Fomicheva, L. N.; Tsvyashchenko, A. V.; Grigoriev, S. V.

2018-04-01

The mesostructure of transition-metal monogermanides Mn1 - x Co x Ge is studied by small-angle neutron scattering in a wide range of concentrations x = 0-0.95. These compounds were synthesized under high pressure and are metastable under normal conditions. The experimental dependences I( Q) obtained for the whole series of samples in the range of transferred momenta (6 × 10-2 nm-1 < Q< 2.5 nm-1) are described by the power dependence Q - n with an exponent n = 2.99 ± 0.02, uniquely related to the fractal properties of the system under study. The dependence obtained indicates that the superatomic structure of the samples is characterized by the presence of defects with a spatial organization described by a fractal model with a logarithmic dependence of the correlation function of the defect density. It is interesting to note that such defects are absent in the isostructural FeGe compound, i.e., the experimental dependences of the intensity are described well by the expression Q - n with an exponent n = 4.1 ± 0.1, which demonstrates the presence of crystallites with a uniform density distribution inside and a sharp boundary characterizing the surface.

Redox chemistry and natural organic matter (NOM): Geochemists' dream, analytical chemists' nightmare

USGS Publications Warehouse

Macalady, Donald L.; Walton-Day, Katherine

2011-01-01

Natural organic matter (NOM) is an inherently complex mixture of polyfunctional organic molecules. Because of their universality and chemical reversibility, oxidation/reductions (redox) reactions of NOM have an especially interesting and important role in geochemistry. Variabilities in NOM composition and chemistry make studies of its redox chemistry particularly challenging, and details of NOM-mediated redox reactions are only partially understood. This is in large part due to the analytical difficulties associated with NOM characterization and the wide range of reagents and experimental systems used to study NOM redox reactions. This chapter provides a summary of the ongoing efforts to provide a coherent comprehension of aqueous redox chemistry involving NOM and of techniques for chemical characterization of NOM. It also describes some attempts to confirm the roles of different structural moieties in redox reactions. In addition, we discuss some of the operational parameters used to describe NOM redox capacities and redox states, and describe nomenclature of NOM redox chemistry. Several relatively facile experimental methods applicable to predictions of the NOM redox activity and redox states of NOM samples are discussed, with special attention to the proposed use of fluorescence spectroscopy to predict relevant redox characteristics of NOM samples.

Neutron generation from Z-pinches

NASA Astrophysics Data System (ADS)

Vikhrev, V. V.; Korolev, V. D.

2007-05-01

Recent advances in both experimental and theoretical studies on neutron generation in various Z-pinch facilities are reviewed. The main methods for enhancing neutron emission from the Z-pinch plasma are described, and the problems of igniting a thermonuclear burn wave in this plasma are discussed.

Exploring Chaos: A Case Study.

ERIC Educational Resources Information Center

Nemirovsky, Ricardo; Tinker, Robert

1993-01-01

Describes software, hardware, and devices that were designed to provide students with an environment to experiment with basic ideas of mechanics, including nonlinear dynamics. Examines the behavior of a Lorenzian water wheel by comparing experimental data with theoretical results obtained from computer-based sensors. (MDH)

Effects of ozone on the sporulation, germination, and pathogenicity of Botrytis cinerea

DOE Office of Scientific and Technical Information (OSTI.GOV)

Krause, C.R.; Weidensaul, T.C.

1978-02-01

Studies were initiated to determine if Botrytis cinerea conidia remain viable when grown in vivo and in vitro in the presence of ambient ozone levels and whether ozonized conidia retain pathogenicity. Experimental materials and methods used are described.

Comparative Actions of Barbiturates Studied by Pollen Grain Germination.

ERIC Educational Resources Information Center

Kordan, Herbert A.; Mumford, Pauline M.

1979-01-01

Describes a simple experimental system whereby the comparative actions of long, medium, and short-acting barbiturates can be demonstrated in a relatively short period of time under optical microscopy using pollen grains as the biological test or assay system. (Author/HM)

Brownian Movement and Avogadro's Number: A Laboratory Experiment.

ERIC Educational Resources Information Center

Kruglak, Haym

1988-01-01

Reports an experimental procedure for studying Einstein's theory of Brownian movement using commercially available latex microspheres and a video camera. Describes how students can monitor sphere motions and determine Avogadro's number. Uses a black and white video camera, microscope, and TV. (ML)

Strategies toward Cooperation.

ERIC Educational Resources Information Center

Johnson, Donald A.

1979-01-01

The Quad-Cities Graduate Study Center in Rock Island, Illinois, a voluntary, publicly funded, academic consortium, is described. It was incorporated as an experimental project to determine if pooling institutional resources were academically, financially, and administratively possible. It is now a model of inter-institutional cooperation providing…

Psychosocial Research and the Hospitalized Adolescent: Approaches and Challenges.

ERIC Educational Resources Information Center

Denholm, Carey J.; Joschko, Michael

1988-01-01

Notes that hospitalized adolescents are often participants in psychosocial research. Presents examples of studies within four approaches (instructional, theoretical, informational, experimental) to describe behaviors of hospitalized adolescents. Discusses impact of various illness states (acute, chronic, terminal) and readiness of adolescent to be…

Robotic edge machining using elastic abrasive tool

NASA Astrophysics Data System (ADS)

Sidorova, A. V.; Semyonov, E. N.; Belomestnykh, A. S.

2018-03-01

The article describes a robotic center designed for automation of finishing operations, and analyzes technological aspects of an elastic abrasive tool applied for edge machining. Based on the experimental studies, practical recommendations on the application of the robotic center for finishing operations were developed.

Orbital Energy Levels in Molecular Hydrogen. A Simple Approach.

ERIC Educational Resources Information Center

Willis, Christopher J.

1988-01-01

Described are the energetics involved in the formation of molecular hydrogen using concepts that should be familiar to students beginning the study of molecular orbital theory. Emphasized are experimental data on ionization energies. Included are two-electron atomic and molecular systems. (CW)

Research in general practice--the germination of an idea.

PubMed

Nichols, W P; Dookun, R

1998-09-12

The concept, planning and initiation of a research project into the treatment of temporomandibular dysfunction carried out by a group of GDPs in their own practices is described. Reports of the experimental studies will be presented as a further series of papers.

Experimental Research at the Intensity Frontier in High Energy Physics

DOE Office of Scientific and Technical Information (OSTI.GOV)

Marshak, Marvin L.

2014-06-30

This Final Report describes DOE-supported Intensity Frontier research by the University of Minnesota during the interval April 1, 2011 to March 31, 2014. Primary activities included the MINOS, NOvA and LBNE Experiments and Heavy Quark studies at BES III.

Electric Propulsion: Experimental Research

NASA Technical Reports Server (NTRS)

Ruyten, W. M.; Friedly, V. J.; Keefer, D.

1995-01-01

This paper describes experimental electric propulsion research which was carried out at the University of Tennessee Space Institute with support from the Center for Space Transportation and Applied Research. Specifically, a multiplexed LIF technique for obtaining vector velocities, Doppler temperatures, and relative number densities in the exhaust plumes form electric propulsion devices is described, and results are presented that were obtained on a low power argon arcjet. Also, preliminary Langmuir probe measurements on an ion source are described, and an update on the vacuum facility is presented.

Electric propulsion: Experimental research

NASA Technical Reports Server (NTRS)

Ruyten, W. M.; Friedly, V. J.; Keefer, D.

1992-01-01

This paper describes experimental electric propulsion research which was carried out at the University of Tennessee Space Institute with support from the Center for Space Transportation and Applied Research. Specifically, a multiplexed laser induced fluorescence (LIF) technique for obtaining vector velocities, Doppler temperatures, and relative number densities in the exhaust plumes from electric propulsion devices is described, and results are presented that were obtained on a low power argon arcjet. Also, preliminary Langmuir probe measurements on an ion source are described, and an update on the vacuum facility is presented.

Toward a community ecology of landscapes: predicting multiple predator-prey interactions across geographic space.

PubMed

Schmitz, Oswald J; Miller, Jennifer R B; Trainor, Anne M; Abrahms, Briana

2017-09-01

Community ecology was traditionally an integrative science devoted to studying interactions between species and their abiotic environments in order to predict species' geographic distributions and abundances. Yet for philosophical and methodological reasons, it has become divided into two enterprises: one devoted to local experimentation on species interactions to predict community dynamics; the other devoted to statistical analyses of abiotic and biotic information to describe geographic distribution. Our goal here is to instigate thinking about ways to reconnect the two enterprises and thereby return to a tradition to do integrative science. We focus specifically on the community ecology of predators and prey, which is ripe for integration. This is because there is active, simultaneous interest in experimentally resolving the nature and strength of predator-prey interactions as well as explaining patterns across landscapes and seascapes. We begin by describing a conceptual theory rooted in classical analyses of non-spatial food web modules used to predict species interactions. We show how such modules can be extended to consideration of spatial context using the concept of habitat domain. Habitat domain describes the spatial extent of habitat space that predators and prey use while foraging, which differs from home range, the spatial extent used by an animal to meet all of its daily needs. This conceptual theory can be used to predict how different spatial relations of predators and prey could lead to different emergent multiple predator-prey interactions such as whether predator consumptive or non-consumptive effects should dominate, and whether intraguild predation, predator interference or predator complementarity are expected. We then review the literature on studies of large predator-prey interactions that make conclusions about the nature of multiple predator-prey interactions. This analysis reveals that while many studies provide sufficient information about predator or prey spatial locations, and thus meet necessary conditions of the habitat domain conceptual theory for drawing conclusions about the nature of the predator-prey interactions, several studies do not. We therefore elaborate how modern technology and statistical approaches for animal movement analysis could be used to test the conceptual theory, using experimental or quasi-experimental analyses at landscape scales. © 2017 by the Ecological Society of America.

IT Control Deficiencies That Affect the Financial Reporting of Companies since the Enactment of the Sarbanes Oxley Act

ERIC Educational Resources Information Center

Harper, Roosevelt

2014-01-01

This research study examined the specific categories of IT control deficiencies and their related effects on financial reporting. The approach to this study was considered non-experimental, an approach sometimes called descriptive. Descriptive statistics are used to describe the basic features of the data in a study, providing simple summaries…

Simulation and experimental analysis of nanoindentation and mechanical properties of amorphous NiAl alloys.

PubMed

Wang, Chih-Hao; Fang, Te-Hua; Cheng, Po-Chien; Chiang, Chia-Chin; Chao, Kuan-Chi

2015-06-01

This paper used numerical and experimental methods to investigate the mechanical properties of amorphous NiAl alloys during the nanoindentation process. A simulation was performed using the many-body tight-binding potential method. Temperature, plastic deformation, elastic recovery, and hardness were evaluated. The experimental method was based on nanoindentation measurements, allowing a precise prediction of Young's modulus and hardness values for comparison with the simulation results. The indentation simulation results showed a significant increase of NiAl hardness and elastic recovery with increasing Ni content. Furthermore, the results showed that hardness and Young's modulus increase with increasing Ni content. The simulation results are in good agreement with the experimental results. Adhesion test of amorphous NiAl alloys at room temperature is also described in this study.

Experimental far-field imaging properties of a ~5-μm diameter spherical lens.

PubMed

Ye, Ran; Ye, Yong-Hong; Ma, Hui Feng; Ma, Jun; Wang, Bin; Yao, Jie; Liu, Shuai; Cao, Lingling; Xu, Huanhuan; Zhang, Jia-Yu

2013-06-01

Microscale lenses are mostly used as near-sighted lenses. The far-field imaging properties of a microscale spherical lens, where the lens is spatially separated from the object, are experimentally studied. Our experimental results show that, for a blu-ray disc (an object) whose spacing is 300 nm, the lens can magnify the stripe patterns of the disc when the lens is spatially separated from the object. In the experimentally tested range (0-14 μm), all the magnified images are virtual images. When the distance is increased from 0 to 14 μm the magnification decreases from 1.47× to 1.20× and the field of view increases from 3.8 to 12.2 μm. The image magnification cannot be described by standard geometrical optics.

Does renal ageing affect survival?

PubMed

Razzaque, M Shawkat

2007-10-01

The effects of ageing on progressive deterioration of renal function, both in human and experimental animals, are described elsewhere, but the effect of renal damage on overall survival and longevity is not yet clearly established. The wild-type animals of various genetic backgrounds, fed with regular diet, overtime develop severe age-associated nephropathy, that include but not limited to inflammatory cell infiltration, glomerulosclerosis, and tubulointerstitial fibrosis. Such renal damage significantly reduces their survival. Reducing renal damage, either by caloric restriction or by suppressing growth hormone (GH)/insulin-like growth factor-1 (IGF-1) activity could significantly enhance the longevity of these animals. Available survival studies using experimental animals clearly suggest that kidney pathology is one of the important non-neoplastic lesions that could affect overall survival, and that restoration of renal function by preventing kidney damage could significantly extend longevity. Careful long-term studies are needed to determine the human relevance of these experimental studies.

Defining body deception and its role in peer based social comparison theories of body dissatisfaction.

PubMed

Hildebrandt, Tom; Shiovitz, Rachel; Alfano, Lauren; Greif, Rebecca

2008-09-01

The purpose of the current study was to operationalize the phenomenon of body deception, describe its theoretical importance, and validate its existence in an experimental paradigm. The definition of body deception includes the intentional misrepresentation of information about appearance to others. The present study examined body deception in a controlled experimental study of male and female same-sex peer groups using a series of hierarchical linear models. Ninety male and 90 female undergraduates were randomized to an experimental same-sex peer group or individual control condition. The results suggested that both men and women used body deception among peers, but men's body deception was muscularity driven whereas women's was thinness driven. Body dissatisfaction was significantly predictive of the degree of body deception used by both genders and it was significantly related to peer group membership. An integrated model for the role of body deception in body image disturbance is proposed.

Highlights of Transient Plume Impingement Model Validation and Applications

NASA Technical Reports Server (NTRS)

Woronowicz, Michael

2011-01-01

This paper describes highlights of an ongoing validation effort conducted to assess the viability of applying a set of analytic point source transient free molecule equations to model behavior ranging from molecular effusion to rocket plumes. The validation effort includes encouraging comparisons to both steady and transient studies involving experimental data and direct simulation Monte Carlo results. Finally, this model is applied to describe features of two exotic transient scenarios involving NASA Goddard Space Flight Center satellite programs.

The application of the integral equation theory to study the hydrophobic interaction

PubMed Central

Mohorič, Tomaž; Urbic, Tomaz; Hribar-Lee, Barbara

2014-01-01

The Wertheim's integral equation theory was tested against newly obtained Monte Carlo computer simulations to describe the potential of mean force between two hydrophobic particles. An excellent agreement was obtained between the theoretical and simulation results. Further, the Wertheim's integral equation theory with polymer Percus-Yevick closure qualitatively correctly (with respect to the experimental data) describes the solvation structure under conditions where the simulation results are difficult to obtain with good enough accuracy. PMID:24437891

Ion beam microtexturing and enhanced surface diffusion

NASA Technical Reports Server (NTRS)

Robinson, R. S.

1982-01-01

Ion beam interactions with solid surfaces are discussed with particular emphasis on microtexturing induced by the deliberate deposition of controllable amounts of an impurity material onto a solid surface while simultaneously sputtering the surface with an ion beam. Experimental study of the optical properties of microtextured surfaces is described. Measurements of both absorptance as a function of wavelength and emissivity are presented. A computer code is described that models the sputtering and ion reflection processes involved in microtexture formation.

Threats to the Internal Validity of Experimental and Quasi-Experimental Research in Healthcare.

PubMed

Flannelly, Kevin J; Flannelly, Laura T; Jankowski, Katherine R B

2018-01-01

The article defines, describes, and discusses the seven threats to the internal validity of experiments discussed by Donald T. Campbell in his classic 1957 article: history, maturation, testing, instrument decay, statistical regression, selection, and mortality. These concepts are said to be threats to the internal validity of experiments because they pose alternate explanations for the apparent causal relationship between the independent variable and dependent variable of an experiment if they are not adequately controlled. A series of simple diagrams illustrate three pre-experimental designs and three true experimental designs discussed by Campbell in 1957 and several quasi-experimental designs described in his book written with Julian C. Stanley in 1966. The current article explains why each design controls for or fails to control for these seven threats to internal validity.

Modeling of Receptor Tyrosine Kinase Signaling: Computational and Experimental Protocols.

PubMed

Fey, Dirk; Aksamitiene, Edita; Kiyatkin, Anatoly; Kholodenko, Boris N

2017-01-01

The advent of systems biology has convincingly demonstrated that the integration of experiments and dynamic modelling is a powerful approach to understand the cellular network biology. Here we present experimental and computational protocols that are necessary for applying this integrative approach to the quantitative studies of receptor tyrosine kinase (RTK) signaling networks. Signaling by RTKs controls multiple cellular processes, including the regulation of cell survival, motility, proliferation, differentiation, glucose metabolism, and apoptosis. We describe methods of model building and training on experimentally obtained quantitative datasets, as well as experimental methods of obtaining quantitative dose-response and temporal dependencies of protein phosphorylation and activities. The presented methods make possible (1) both the fine-grained modeling of complex signaling dynamics and identification of salient, course-grained network structures (such as feedback loops) that bring about intricate dynamics, and (2) experimental validation of dynamic models.

Experimental and Theoretical Study of Heat Conduction for Air up to 5000 K

NASA Technical Reports Server (NTRS)

Peng, Tzy-Cheng; Ahtye, Warren F.

1961-01-01

The theoretical value of the integral of thermal conductivity is compared with the experimental values from shock-tube measurements. The particular case considered is the one-dimensional nonsteady flow of heat through air at constant pressure. This approach has been previously described in NASA TR R-27. experiment was uncertain because of the large scatter in the experimental data. In this paper, an attempt is made to improve the correlation by use of a more refined calculation of the integral of thermal conductivity, and by use of improved experimental techniques and instrumentation. As a result of these changes, a much closer correlation is shown between the experimental and theoretical heat-flux potentials. This indicates that the predicted values of the coefficient of thermal conductivity for high-temperature air may be suitably accurate for many engineering needs, up to the limits of the test (4600 K).

Interventions to Improve Hand Hygiene Compliance in the ICU: A Systematic Review.

PubMed

Lydon, Sinéad; Power, Michael; McSharry, Jennifer; Byrne, Molly; Madden, Caoimhe; Squires, Janet Elaine; O'Connor, Paul

2017-11-01

To synthesize the literature describing interventions to improve hand hygiene in ICUs, to evaluate the quality of the extant research, and to outline the type, and efficacy, of interventions described. Systematic searches were conducted in November 2016 using five electronic databases: Medline, CINAHL, PsycInfo, Embase, and Web of Science. Additionally, the reference lists of included studies and existing review papers were screened. English language, peer-reviewed studies that evaluated an intervention to improve hand hygiene in an adult ICU setting, and reported hand hygiene compliance rates collected via observation, were included. Data were extracted on the setting, participant characteristics, experimental design, hand hygiene measurement, intervention characteristics, and outcomes. Interventional components were categorized using the Behavior Change Wheel. Methodological quality was examined using the Downs and Black Checklist. Thirty-eight studies were included. The methodological quality of studies was poor, with studies scoring a mean of 8.6 of 24 (SD= 2.7). Over 90% of studies implemented a bundled intervention. The most frequently employed interventional strategies were education (78.9%), enablement (71.1%), training (68.4%), environmental restructuring (65.8%), and persuasion (65.8%). Intervention outcomes were variable, with a mean relative percentage change of 94.7% (SD= 195.7; range, 4.3-1155.4%) from pre to post intervention. This review demonstrates that best practice for improving hand hygiene in ICUs remains unestablished. Future research employing rigorous experimental designs, careful statistical analysis, and clearly described interventions is important.

Experimental Validation of an Integrated Controls-Structures Design Methodology

NASA Technical Reports Server (NTRS)

Maghami, Peiman G.; Gupta, Sandeep; Elliot, Kenny B.; Walz, Joseph E.

1996-01-01

The first experimental validation of an integrated controls-structures design methodology for a class of large order, flexible space structures is described. Integrated redesign of the controls-structures-interaction evolutionary model, a laboratory testbed at NASA Langley, was described earlier. The redesigned structure was fabricated, assembled in the laboratory, and experimentally tested against the original structure. Experimental results indicate that the structure redesigned using the integrated design methodology requires significantly less average control power than the nominal structure with control-optimized designs, while maintaining the required line-of-sight pointing performance. Thus, the superiority of the integrated design methodology over the conventional design approach is experimentally demonstrated. Furthermore, amenability of the integrated design structure to other control strategies is evaluated, both analytically and experimentally. Using Linear-Quadratic-Guassian optimal dissipative controllers, it is observed that the redesigned structure leads to significantly improved performance with alternate controllers as well.

Gaseous Sulfate Solubility in Glass: Experimental Method

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bliss, Mary

2013-11-30

Sulfate solubility in glass is a key parameter in many commercial glasses and nuclear waste glasses. This report summarizes key publications specific to sulfate solubility experimental methods and the underlying physical chemistry calculations. The published methods and experimental data are used to verify the calculations in this report and are expanded to a range of current technical interest. The calculations and experimental methods described in this report will guide several experiments on sulfate solubility and saturation for the Hanford Waste Treatment Plant Enhanced Waste Glass Models effort. There are several tables of sulfate gas equilibrium values at high temperature tomore » guide experimental gas mixing and to achieve desired SO3 levels. This report also describes the necessary equipment and best practices to perform sulfate saturation experiments for molten glasses. Results and findings will be published when experimental work is finished and this report is validated from the data obtained.« less

The Challenges of Analyzing Behavioral Response Study Data: An Overview of the MOCHA (Multi-study OCean Acoustics Human Effects Analysis) Project.

PubMed

Harris, Catriona M; Thomas, Len; Sadykova, Dina; DeRuiter, Stacy L; Tyack, Peter L; Southall, Brandon L; Read, Andrew J; Miller, Patrick J O

2016-01-01

This paper describes the MOCHA project which aims to develop novel approaches for the analysis of data collected during Behavioral Response Studies (BRSs). BRSs are experiments aimed at directly quantifying the effects of controlled dosages of natural or anthropogenic stimuli (typically sound) on marine mammal behavior. These experiments typically result in low sample size, relative to variability, and so we are looking at a number of studies in combination to maximize the gain from each one. We describe a suite of analytical tools applied to BRS data on beaked whales, including a simulation study aimed at informing future experimental design.

Investigation of air cleaning system response to accident conditions

DOE Office of Scientific and Technical Information (OSTI.GOV)

Andrae, R.W.; Bolstad, J.W.; Foster, R.D.

1980-01-01

Air cleaning system response to the stress of accident conditions are being investigated. A program overview and hghlight recent results of our investigation are presented. The program includes both analytical and experimental investigations. Computer codes for predicting effects of tornados, explosions, fires, and material transport are described. The test facilities used to obtain supportive experimental data to define structural integrity and confinement effectiveness of ventilation system components are described. Examples of experimental results for code verification, blower response to tornado transients, and filter response to tornado and explosion transients are reported.

Development of an Agent-Based Model (ABM) to Simulate the Immune System and Integration of a Regression Method to Estimate the Key ABM Parameters by Fitting the Experimental Data

PubMed Central

Tong, Xuming; Chen, Jinghang; Miao, Hongyu; Li, Tingting; Zhang, Le

2015-01-01

Agent-based models (ABM) and differential equations (DE) are two commonly used methods for immune system simulation. However, it is difficult for ABM to estimate key parameters of the model by incorporating experimental data, whereas the differential equation model is incapable of describing the complicated immune system in detail. To overcome these problems, we developed an integrated ABM regression model (IABMR). It can combine the advantages of ABM and DE by employing ABM to mimic the multi-scale immune system with various phenotypes and types of cells as well as using the input and output of ABM to build up the Loess regression for key parameter estimation. Next, we employed the greedy algorithm to estimate the key parameters of the ABM with respect to the same experimental data set and used ABM to describe a 3D immune system similar to previous studies that employed the DE model. These results indicate that IABMR not only has the potential to simulate the immune system at various scales, phenotypes and cell types, but can also accurately infer the key parameters like DE model. Therefore, this study innovatively developed a complex system development mechanism that could simulate the complicated immune system in detail like ABM and validate the reliability and efficiency of model like DE by fitting the experimental data. PMID:26535589

Martians R Us.

ERIC Educational Resources Information Center

West, Rose

1988-01-01

Describes a science activity done with sixth graders during a unit on outer space. Uses the "Discovery Lab" software program to introduce controlled and experimental variables to the children. Discusses the coordination of library research, computer time, and creative drawing to study planetary environments by designing representative aliens. (CW)

Empathy, Projection and Negation in Seven Countries.

ERIC Educational Resources Information Center

Alexander, Ralph A.; And Others

This report describes an experimental study designed to manipulate and test cross-cultural similarities and differences in interpersonal perception despite the increasingly cosmopolitan nature of people from all cultures, greater frequency of social, business, educational and governmental contact among people from different countries, and the…

Experiment in the Bragg Reflection of Light for the Undergraduate Using Cholesteric Liquid Crystals

ERIC Educational Resources Information Center

Olah, A.; Doane, J. W.

1977-01-01

Describes a simple experimental setup in which the student can detect and record light spectra, study and test the concept of Bragg reflection, and measure the anisotropy of the index of refraction in a cholesteric liquid crystal. (MLH)

A Simple Adsorption Experiment

ERIC Educational Resources Information Center

Guirado, Gonzalo; Ayllon, Jose A.

2011-01-01

The study of adsorption phenomenon is one of the most relevant and traditional physical chemistry experiments performed by chemistry undergraduate students in laboratory courses. In this article, we describe an easy, inexpensive, and straightforward way to experimentally determine adsorption isotherms using pieces of filter paper as the adsorbent…

THE EMPACT BEACHES: A CASE STUDY IN RECREATIONAL WATER SAMPLING

EPA Science Inventory

Various chapters describe sample and experimental design, use of a geometric mean or an arithmetic mean, modeling and forecasting, and risk assessment in relation to monitoring recreational waters for fecal indicators. All of these aspects of monitoring are dependent on the spat...

Who's Afraid of Something New?

ERIC Educational Resources Information Center

Learning Today, 1973

1973-01-01

Metro High, St. Louis, is described in pictures and words. The school, started in 1972, is a small, experimental school, which encourages self instruction, community involvement, and the use of real situations as learning experiences. The Zoology class, for instance, visits the zoo to study the animals. (SM)

Supersonic flow with feeding of energy

NASA Technical Reports Server (NTRS)

Zaremba, W.

1985-01-01

The present work discusses the results of some experimental studies on the possibility of attenuating shock waves in a supersonic flow. The shock waves were formed by an external source of electrical energy. An electromechanical method is described that permits partial recovery of the expended energy.

Executive report: Results of the IRGA-CNPq/INPE experimental project

NASA Technical Reports Server (NTRS)

Deassuncao, G. V. (Principal Investigator); Novaes, R. A.; Moreira, M. A.

1983-01-01

A methodology for identifying and evaluating crop area with irrigated rice is described, using MSS-LANDSAT data. The maps of the spatial rice crop areas in the studied region are presented. The calculation of rice growing area from the LANDSAT images are included.

Functionalized lipids and surfactants for specific applications.

PubMed

Kepczynski, Mariusz; Róg, Tomasz

2016-10-01

Synthetic lipids and surfactants that do not exist in biological systems have been used for the last few decades in both basic and applied science. The most notable applications for synthetic lipids and surfactants are drug delivery, gene transfection, as reporting molecules, and as support for structural lipid biology. In this review, we describe the potential of the synergistic combination of computational and experimental methodologies to study the behavior of synthetic lipids and surfactants embedded in lipid membranes and liposomes. We focused on select cases in which molecular dynamics simulations were used to complement experimental studies aiming to understand the structure and properties of new compounds at the atomistic level. We also describe cases in which molecular dynamics simulations were used to design new synthetic lipids and surfactants, as well as emerging fields for the application of these compounds. This article is part of a Special Issue entitled: Biosimulations edited by Ilpo Vattulainen and Tomasz Róg. Copyright © 2016 Elsevier B.V. All rights reserved.

Development and application of an exchange model for anisotropic water diffusion in the microporous MOF aluminum fumarate

NASA Astrophysics Data System (ADS)

Splith, Tobias; Fröhlich, Dominik; Henninger, Stefan K.; Stallmach, Frank

2018-06-01

Diffusion of water in aluminum fumarate was studied by means of pulsed field gradient (PFG) nuclear magnetic resonance (NMR). Due to water molecules exchanging between the intracrystalline anisotropic pore space and the isotropic intercrystalline void space the model of intracrystalline anisotropic diffusion fails to describe the experimental PFG NMR data at high observation times. Therefore, the two-site exchange model developed by Kärger is extended to the case of exchange between an anisotropic and an isotropic site. This extended exchange model is solved by numerical integration. It describes the experimental data very well and yields values for the intracrystalline diffusion coefficient and the mean residence times of the respective sites. Further PFG NMR studies were performed with coatings consisting of small aluminum fumarate crystals, which are used in adsorptive heat transformation applications. The diffusion coefficients of water in the small crystal coating are compared to the values expected from the extended two-site exchange model and from the model of long-range diffusion.

Manual of Scaling Methods

NASA Technical Reports Server (NTRS)

Bond, Thomas H. (Technical Monitor); Anderson, David N.

2004-01-01

This manual reviews the derivation of the similitude relationships believed to be important to ice accretion and examines ice-accretion data to evaluate their importance. Both size scaling and test-condition scaling methods employing the resulting similarity parameters are described, and experimental icing tests performed to evaluate scaling methods are reviewed with results. The material included applies primarily to unprotected, unswept geometries, but some discussion of how to approach other situations is included as well. The studies given here and scaling methods considered are applicable only to Appendix-C icing conditions. Nearly all of the experimental results presented have been obtained in sea-level tunnels. Recommendations are given regarding which scaling methods to use for both size scaling and test-condition scaling, and icing test results are described to support those recommendations. Facility limitations and size-scaling restrictions are discussed. Finally, appendices summarize the air, water and ice properties used in NASA scaling studies, give expressions for each of the similarity parameters used and provide sample calculations for the size-scaling and test-condition scaling methods advocated.

A Study of the Destruction of Spacecraft Surfaces at Contact Interactions with Microparticles of the Space Environment

NASA Astrophysics Data System (ADS)

Sidnyaev, N. I.

2018-05-01

The results of studying the high-velocity impact interactions of a particle flux of space's meteoric background with satellites have been presented. The effects that arises during the microparticle motion in the material have been described; the models of solid particle interactions with spacecraft's onboard hardware protection have been presented. The experimental and analytical dependences have been given. The basic factors have been revealed, and their effect on the erosion wear of satellite's surface has been estimated. The dependences for calculating the rectilinear (horizontal, inclined and vertical) sections of satellite's surface have been given. The presented dependences represent the results of experimental and analytical studies.

Kinetic studies of the yeast His-Asp phosphorelay signaling pathway

PubMed Central

Kaserer, Alla O.; Andi, Babak; Cook, Paul F.; West, Ann H.

2010-01-01

For both prokaryotic and eukaryotic His-Asp phosphorelay signaling pathways, the rates of protein phosphorylation and dephosphorylation determine the stimulus-to-response time frame. Thus, kinetic studies of phosphoryl group transfer between signaling partners are important for gaining a full understanding of how the system is regulated. In many cases, the phosphotransfer reactions are too fast for rates to be determined by manual experimentation. Rapid quench flow techniques thus provide a powerful method for studying rapid reactions that occur in the millisecond time frame. In this chapter, we describe experimental design and procedures for kinetic characterization of the yeast SLN1-YPD1-SSK1 osmoregulatory phosphorelay system using a rapid quench flow kinetic instrument. PMID:20946842

Method for Studying Helicopter Longitudinal Maneuver Stability

NASA Technical Reports Server (NTRS)

Amer, Kenneth B

1954-01-01

A theoretical analysis of helicopter maneuver stability is made and the results are compared with experimental results for both a single and a tandem rotor helicopter. Techniques are described for measuring in flight the significant stability derivatives for use with the theory to aid in design studies of means for achieving marginal maneuver stability for a prototype helicopter.

An Experimental Study of Contaminant Intrusion Through Pipe Cracks

EPA Science Inventory

This report describes a series of experiments conducted at U.S. EPA’s Test and Evaluation Facility in 2013-2014 to study the intrusion of contaminated soil water into a pipe crack during simulated backflow events. A test rig was used consisting of a 3’ x 3’ x 3’ acrylic soil bo...

Results from recent NASA tire thermal studies

NASA Technical Reports Server (NTRS)

Mccarty, J. L.

1983-01-01

The testing technique and some results from an experimental study to determine tire temperature profiles to aid in defining the strength and fatigue limitations of the tire carcass structure are described. This effort is part of a program to explore analytically and through experiment the temperature distribution in an aircraft tire during free roll and braked and yawed rolling conditions.

Frozen by Fear: Can Digital Scaffolding Help Students Start Writing?

ERIC Educational Resources Information Center

Mills, Daniel; Kennedy, Olivia

2013-01-01

Despite having studied English for some 33 months, the students at the private junior high school in Japan described in this paper had never before been asked to write original compositions in the language. The researchers undertook a quasi-experimental pilot study in which the 156 (n= 156) participants were each asked to write four compositions,…

Supersonic Leading Edge Receptivity

NASA Technical Reports Server (NTRS)

Maslov, Anatoly A.

1998-01-01

This paper describes experimental studies of leading edge boundary layer receptivity for imposed stream disturbances. Studies were conducted in the supersonic T-325 facility at ITAM and include data for both sharp and blunt leading edges. The data are in agreement with existing theory and should provide guidance for the development of more complete theories and numerical computations of this phenomena.

Effect of Posttraumatic Stress on Study Time in a Task Measuring Four Component Processes Underlying Text-Level Reading

ERIC Educational Resources Information Center

Sullivan, Michael P.; Griffiths, Gina G.; Sohlberg, Mckay Moore

2014-01-01

Purpose: To investigate the effect of combat-related posttraumatic stress disorder (PTSD) on 4 components underlying text-level reading comprehension. Method: A group of 17 veterans with PTSD and 17 matched control participants took part. An experimental task required participants to read and study 3-sentence paragraphs describing semantic…

Description of the Fork Mountain long-term soil productivity study: site characterization

Treesearch

Mary Beth Adams; James Burger; Lucian Zelazny; John Baumgras

2004-01-01

The effects of air pollution and timber harvesting on soil resources continue to be an important issue in eastern hardwood forests. This publication describes the Fork Mountain Long-term Soil Productivity Study (LTSP), located on the Fernow Experimental Forest, WV, and the pretreatment stand, soil and climatic conditions. Extensive vegetation surveys, biomass...

Improving Students' Conceptual Understanding of a Specific Content Learning: A Designed Teaching Sequence

ERIC Educational Resources Information Center

Ahmad, N. J.; Lah, Y. Che

2012-01-01

The efficacy of a teaching sequence designed for a specific content of learning of electrochemistry is described in this paper. The design of the teaching draws upon theoretical insights into perspectives on learning and empirical studies to improve the teaching of this topic. A case study involving two classes, the experimental and baseline…

How Analogue Research Can Advance Descriptive Evaluation Theory: Understanding (and Improving) Stakeholder Dialogue

ERIC Educational Resources Information Center

Campbell, Bernadette; Mark, Melvin M.

2015-01-01

Evaluation theories can be tested in various ways. One approach, the experimental analogue study, is described and illustrated in this article. The approach is presented as a method worthy to use in the pursuit of what Alkin and others have called descriptive evaluation theory. Drawing on analogue studies conducted by the first author, we…

Aerothermodynamics research at NASA Ames Research Center

NASA Technical Reports Server (NTRS)

Deiwert, George S.

1987-01-01

Research activity in the aerothermodynamics branch at the NASA Ames Research Center is reviewed. Advanced concepts and mission studies relating to the next generation aerospace transportation systems are summarized and directions for continued research identified. Theoretical and computational studies directed at determining flow fields and radiative and convective heating loads in real gases are described. Included are Navier-Stokes codes for equilibrium and thermochemical nonequilibrium air. Experimental studies in the 3.5-ft hypersonic wind tunnel, the ballistic ranges, and the electric arc driven shock tube are described. Tested configurations include generic hypersonic aerospace plane configurations, aeroassisted orbital transfer vehicle shapes and Galileo probe models.

Physics, mathematics and numerics of particle adsorption on fluid interfaces

NASA Astrophysics Data System (ADS)

Schmuck, Markus; Pavliotis, Grigorios A.; Kalliadasis, Serafim

2012-11-01

We study two arbitrary immiscible fuids where one phase contains small particles of the size of the interface and smaller. We primarily focus on charge-free particles with wetting characteristics described by the contact angle formed at the interface between the two phases and the particles. Based on the experimental observation that particles are adsorbed on the interface to reduce the interfacial energy and hence the surface tension as well, we formulate a free-energy functional that accounts for these physical effects. Using elements from calculus of variations and formal gradient flow theory, we derive partial differential equations describing the location of the interface and the density of the particles in the fluid phases. Via numerical experiments we analyse the time evolution of the surface tension, the particle concentration, and the free energy over time and reflect basic experimentally observed phenomena.

Secondary school physics teachers' conceptions of scientific evidence: A collective case study

NASA Astrophysics Data System (ADS)

Taylor, Joseph A.

Engaging secondary school students in inquiry-oriented tasks that more closely simulate the scholarly activities of scientists has been recommended as a way to improve scientific literacy. Two tasks that are frequently recommended include students' design of original experiments, and students' evaluation of scientific evidence and conclusions. Yet, little is known about teachers' conceptions of experimentation. The principal aim of this study, therefore, was to describe the nature of prospective and practicing physics teachers' conceptions of scientific evidence. More specifically, the following research questions guided this study: (1) What types of issues related to the measurement reliability and experimental validity of scientific evidence do practicing and prospective physics teachers think about when designing experiments? (2) When presented with hypothetical scenarios that describe unsound experimental procedures or poorly supported conclusions (or both), what concerns will prospective and practicing physics teachers raise? And (3) When the participants' responses to parallel research prompts are compared across protocols, what similarities and differences exist? The nature of the teacher-participants' conceptions was described from an analysis of data collected from research prompts such as interviews and hand written artifacts. In these research prompts, the teachers "thought aloud" while designing experiments and critically evaluated student-collected evidence presented in hypothetical classroom scenarios. The data from this study suggested that the three teachers, while contemplating the reliability and validity of scientific evidence, frequently used their conceptions of evidence in conjunction with specific subject matter conceptions. The data also indicated that the relationship between subject matter knowledge and conceptions of evidence was more pronounced for some conceptions of evidence than for others. Suggestions for future research included conducting similar studies in other physics content areas as well as other scientific disciplines. Implications for science teacher education suggested that science and science methods courses encourage the construction of evidence-based arguments, as well as engagement in peer review and critique.

Investigation of the feasibility of optical diagnostic measurements at the exit of the SSME

NASA Technical Reports Server (NTRS)

Shirley, John A.; Boedeker, Laurence R.

1993-01-01

Under Contract NAS8-36861 sponsored by NASA Marshall Space Flight Center, the United Technologies Research Center is conducting an investigation of the feasibility of remote optical diagnostics to measure temperature, species concentration and velocity at the exit of the Space Shuttle Main Engine (SSME). This is a two phase study consisting of a conceptual design phase followed by a laboratory experimental investigation. The first task of the conceptual design studies is to screen and evaluate the techniques which can be used for the measurements. The second task is to select the most promising technique or techniques, if as expected, more than one type of measurement must be used to measure all the flow variables of interest. The third task is to examine in detail analytically the capabilities and limitations of the selected technique(s). The results of this study are described in the section of this report entitled Conceptual Design Investigations. The conceptual design studies identified spontaneous Raman scattering and photodissociative flow-tagging for measurements respectively of gas temperature and major species concentration and for velocity. These techniques and others that were considered are described in the section describing the conceptual design. The objective of the second phase of investigations was to investigate experimentally the techniques identified in the first phase. The first task of the experimental feasibility study is to design and assemble laboratory scale experimental apparatus to evaluate the best approaches for SSME exit optical diagnostics for temperature, species concentrations and velocity, as selected in the Phase I conceptual design study. The second task is to evaluate performance, investigate limitations, and establish actual diagnostic capabilities, accuracies and precision for the selected optical systems. The third task is to evaluate design requirements and system trade-offs of conceptual instruments. Spontaneous Raman scattering excited by a KrF excimer laser pulse was investigated for SSME exit plane temperature and major species concentration measurements. The relative concentrations of molecular hydrogen and water vapor would be determined by measuring the integrated Q-branch scattering signals through narrow bandpass filters in front of photomultipliers. The temperature would be determined by comparing the signal from a single hydrogen rotational Raman line to the total hydrogen Q-branch signal. The rotational Raman line would be isolated by a monochromator and detected with a PMT.

First-principles calculations, experimental study, and thermodynamic modeling of the Al-Co-Cr system.

PubMed

Liu, Xuan L; Gheno, Thomas; Lindahl, Bonnie B; Lindwall, Greta; Gleeson, Brian; Liu, Zi-Kui

2015-01-01

The phase relations and thermodynamic properties of the condensed Al-Co-Cr ternary alloy system are investigated using first-principles calculations based on density functional theory (DFT) and phase-equilibria experiments that led to X-ray diffraction (XRD) and electron probe micro-analysis (EPMA) measurements. A thermodynamic description is developed by means of the calculations of phase diagrams (CALPHAD) method using experimental and computational data from the present work and the literature. Emphasis is placed on modeling the bcc-A2, B2, fcc-γ, and tetragonal-σ phases in the temperature range of 1173 to 1623 K. Liquid, bcc-A2 and fcc-γ phases are modeled using substitutional solution descriptions. First-principles special quasirandom structures (SQS) calculations predict a large bcc-A2 (disordered)/B2 (ordered) miscibility gap, in agreement with experiments. A partitioning model is then used for the A2/B2 phase to effectively describe the order-disorder transitions. The critically assessed thermodynamic description describes all phase equilibria data well. A2/B2 transitions are also shown to agree well with previous experimental findings.

Enhanced magneto-optical imaging of internal stresses in the removed surface layer

NASA Astrophysics Data System (ADS)

Agalidi, Yuriy; Kozhukhar, Pavlo; Levyi, Sergii; Turbin, Dmitriy

2015-10-01

The paper describes a software method of reconstructing the state of the removed surface layer by visualising internal stresses in the underlying layers of the sample. Such a problem typically needs to be solved as part of forensic investigation that aims to reveal original marking of a sample with removed surface layer. For example, one may be interested in serial numbers of weapons or vehicles that had the surface layer of metal removed from the number plate. Experimental results of studying gradient internal stress fields in ferromagnetic sample using the NDI method of magneto-optical imaging (MOI) are presented. Numerical modelling results of internal stresses enclosed in the surface marking region are analysed and compared to the experimental results of magneto-optical imaging (MOI). MOI correction algorithm intended for reconstructing internal stress fields in the removed surface layer by extracting stresses retained by the underlying layers is described. Limiting ratios between parameters of a marking font are defined for the considered correction algorithm. Enhanced recognition properties for hidden stresses left by marking symbols are experimentally verified and confirmed.

Generalized theory of semiflexible polymers.

PubMed

Wiggins, Paul A; Nelson, Philip C

2006-03-01

DNA bending on length scales shorter than a persistence length plays an integral role in the translation of genetic information from DNA to cellular function. Quantitative experimental studies of these biological systems have led to a renewed interest in the polymer mechanics relevant for describing the conformational free energy of DNA bending induced by protein-DNA complexes. Recent experimental results from DNA cyclization studies have cast doubt on the applicability of the canonical semiflexible polymer theory, the wormlike chain (WLC) model, to DNA bending on biologically relevant length scales. This paper develops a theory of the chain statistics of a class of generalized semiflexible polymer models. Our focus is on the theoretical development of these models and the calculation of experimental observables. To illustrate our methods, we focus on a specific, illustrative model of DNA bending. We show that the WLC model generically describes the long-length-scale chain statistics of semiflexible polymers, as predicted by renormalization group arguments. In particular, we show that either the WLC or our present model adequately describes force-extension, solution scattering, and long-contour-length cyclization experiments, regardless of the details of DNA bend elasticity. In contrast, experiments sensitive to short-length-scale chain behavior can in principle reveal dramatic departures from the linear elastic behavior assumed in the WLC model. We demonstrate this explicitly by showing that our toy model can reproduce the anomalously large short-contour-length cyclization factors recently measured by Cloutier and Widom. Finally, we discuss the applicability of these models to DNA chain statistics in the context of future experiments.

Experimental Course Development in Introductory Economics at Indiana University. The Journal of Economic Education, Special Issue No. 4, Fall 1975.

ERIC Educational Resources Information Center

Saunders, Phillip

A two part experimental introductory college economics course is described. Data on the combination macroeconomics and microeconomics course have been collected over eight consecutive terms and are presented in nine chapters. Chapter I describes course goals as stimulation of student interest, teaching a few basic economic principles, helping…

High frequency, high temperature specific core loss and dynamic B-H hysteresis loop characteristics of soft magnetic alloys

NASA Technical Reports Server (NTRS)

Wieserman, W. R.; Schwarze, G. E.; Niedra, J. M.

1990-01-01

Limited experimental data exists for the specific core loss and dynamic B-H loops for soft magnetic materials for the combined conditions of high frequency and high temperature. This experimental study investigates the specific core loss and dynamic B-H loop characteristics of Supermalloy and Metglas 2605SC over the frequency range of 1 to 50 kHz and temperature range of 23 to 300 C under sinusoidal voltage excitation. The experimental setup used to conduct the investigation is described. The effects of the maximum magnetic flux density, frequency, and temperature on the specific core loss and on the size and shape of the B-H loops are examined.

Experimental results on chiral magnetic and vortical effects

DOE PAGES

Wang, Gang; Wen, Liwen

2017-01-12

Various novel transport phenomena in chiral systems result from the interplay of quantum anomalies with magnetic field and vorticity in high-energy heavy-ion collisions and could survive the expansion of the fireball and be detected in experiments. Among them are the chiral magnetic effect, the chiral vortical effect, and the chiral magnetic wave, the experimental searches for which have aroused extensive interest. As a result, the goal of this review is to describe the current status of experimental studies at Relativistic Heavy-Ion Collider at BNL and the Large Hadron Collider at CERN and to outline the future work in experiment neededmore » to eliminate the existing uncertainties in the interpretation of the data.« less

Experimental research on air propellers

NASA Technical Reports Server (NTRS)

Durand, William F

1918-01-01

The purposes of the experimental investigation on the performance of air propellers described in this report are as follows: (1) the development of a series of design factors and coefficients drawn from model forms distributed with some regularity over the field of air-propeller design and intended to furnish a basis of check with similar work done in other aerodynamic laboratories, and as a point of departure for the further study of special or individual types and forms; (2) the establishment of a series of experimental values derived from models and intended for later use as a basis for comparison with similar results drawn from certain selected full-sized forms and tested in free flight.

The experimental results of AMTEC and a study of its terrestrial applications in IEE of China

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ni, Q.; Tong, J.; Kan, Y.

1997-12-31

The R and D activities in the field of AMTEC research at The Institute of Electrical Engineering, Chinese Academy of Sciences are introduced. The outline of experimental facility with a single tube cell is described. The experimental results so far are reported followed by an analysis of electrical characteristic, in particular, an evaluation of characteristic of BASE/porous electrode interface with the effective sheet resistivity and the electrode efficiency. The approaches for improving device performance are discussed. The terrestrial applications of AMTEC in China are considered as an alternative of conventional diesel-generators. The possibility of AMTEC power supply for some separatemore » sites is predicted.« less

Quantifying auditory handicap. A new approach.

PubMed

Jerger, S; Jerger, J

1979-01-01

This report describes a new audiovisual test procedure for the quantification of auditory handicap (QUAH). The QUAH test attempts to recreate in the laboratory a series of everyday listening situations. Individual test items represent psychomotor tasks. Data on 53 normal-hearing listeners described performance as a function of the message-to-competition ratio (MCR). Results indicated that, for further studies, an MCR of 0 dB represents the condition above which the task seemed too easy and below which the task appeared too difficult for normal-hearing subjects. The QUAH approach to the measurement of auditory handicap seems promising as an experimental tool. Further studies are needed to describe the relation of QUAH results (1) to clinical audiologic measures and (2) to more traditional indices of auditory handicap.

Experimental Design for Hanford Low-Activity Waste Glasses with High Waste Loading

DOE Office of Scientific and Technical Information (OSTI.GOV)

Piepel, Gregory F.; Cooley, Scott K.; Vienna, John D.

This report discusses the development of an experimental design for the initial phase of the Hanford low-activity waste (LAW) enhanced glass study. This report is based on a manuscript written for an applied statistics journal. Appendices A, B, and E include additional information relevant to the LAW enhanced glass experimental design that is not included in the journal manuscript. The glass composition experimental region is defined by single-component constraints (SCCs), linear multiple-component constraints (MCCs), and a nonlinear MCC involving 15 LAW glass components. Traditional methods and software for designing constrained mixture experiments with SCCs and linear MCCs are not directlymore » applicable because of the nonlinear MCC. A modification of existing methodology to account for the nonlinear MCC was developed and is described in this report. One of the glass components, SO 3, has a solubility limit in glass that depends on the composition of the balance of the glass. A goal was to design the experiment so that SO 3 would not exceed its predicted solubility limit for any of the experimental glasses. The SO 3 solubility limit had previously been modeled by a partial quadratic mixture model expressed in the relative proportions of the 14 other components. The partial quadratic mixture model was used to construct a nonlinear MCC in terms of all 15 components. In addition, there were SCCs and linear MCCs. This report describes how a layered design was generated to (i) account for the SCCs, linear MCCs, and nonlinear MCC and (ii) meet the goals of the study. A layered design consists of points on an outer layer, and inner layer, and a center point. There were 18 outer-layer glasses chosen using optimal experimental design software to augment 147 existing glass compositions that were within the LAW glass composition experimental region. Then 13 inner-layer glasses were chosen with the software to augment the existing and outer-layer glasses. The experimental design was completed by a center-point glass, a Vitreous State Laboratory glass, and replicates of the center point and Vitreous State Laboratory glasses.« less

An Experimental Study of Men's and Women's Personal Ads.

PubMed

Strassberg, Donald S; English, Brittany L

2015-11-01

Personal ads have long served as a potentially rich source of information for social scientists regarding what women and men appear to be looking for in a partner and what they believe potential partners are looking for in them. Almost every study of this type has content analyzed existing personal ads in print media or, more recently, on the Internet. Many of the limits of this research approach were addressed in a study by Strassberg and Holty (2003) utilizing an experimental research design. Contrary to theory, prior research, and prediction, the most popular female seeking male (FSM) ad in that study was one in which the woman described herself as "financially independent, successful [and] ambitious," producing over 50 % more responses than the next most popular ad, describing the writer as "very attractive and slim." The present study replicated the Strassberg and Holty methodology, placing the same fictitious MSF and FSM personal ads using far more accessible Internet personal ad sites. Contrary to the previous finding, but consistent with evolutionary theories and social psychological experiments (e.g., Townsend & Wasserman, 1998), ads that presented the woman as attractive and the man as financially successful elicited the most interest.

The role of picture of process (pp) on senior high school students’ collision concept learning activities and multirepresentation ability

NASA Astrophysics Data System (ADS)

Sutarto; Indrawati; Wicaksono, I.

2018-04-01

The objectives of the study are to describe the effect of PP collision concepts to high school students’ learning activities and multirepresentation abilities. This study was a quasi experimental with non- equivalent post-test only control group design. The population of this study were students who will learn the concept of collision in three state Senior High Schools in Indonesia, with a sample of each school 70 students, 35 students as an experimental group and 35 students as a control group. Technique of data collection were observation and test. The data were analized by descriptive and inferensial statistic. Student learning activities were: group discussions, describing vectors of collision events, and formulating problem-related issues of impact. Multirepresentation capabilities were student ability on image representation, verbal, mathematics, and graph. The results showed that the learning activities in the three aspects for the three high school average categorized good. The impact of using PP on students’ ability on image and graph representation were a significant impact, but for verbal and mathematical skills there are differences but not significant.

The Experimental Cloud Lidar Pilot Study (ECLIPS) for cloud-radiation research

NASA Technical Reports Server (NTRS)

Platt, C. M.; Young, S. A.; Carswell, A. I.; Pal, S. R.; Mccormick, M. P.; Winker, D. M.; Delguasta, M.; Stefanutti, L.; Eberhard, W. L.; Hardesty, M.

1994-01-01

The Experimental Cloud Lidar Pilot Study (ECLIPS) was initiated to obtain statistics on cloud-base height, extinction, optical depth, cloud brokenness, and surface fluxes. Two observational phases have taken place, in October-December 1989 and April-July 1991, with intensive 30-day periods being selected within the two time intervals. Data are being archived at NASA Langley Research Center and, once there, are readily available to the international scientific community. This article describes the scale of the study in terms of its international involvement and in the range of data being recorded. Lidar observations of cloud height and backscatter coefficient have been taken from a number of ground-based stations spread around the globe. Solar shortwave and infrared longwave fluxes and infrared beam radiance have been measured at the surface wherever possible. The observations have been tailored to occur around the overpass times of the NOAA weather satellites. This article describes in some detail the various retrieval methods used to obtain results on cloud-base height, extinction coefficient, and infrared emittance, paying particular attention to the uncertainties involved.

Systematic study of the effect of HSE functional internal parameters on the electronic structure and band gap of a representative set of metal oxides.

PubMed

Viñes, Francesc; Lamiel-García, Oriol; Chul Ko, Kyoung; Yong Lee, Jin; Illas, Francesc

2017-04-30

The effect of the amount of Hartree-Fock mixing parameter (α) and of the screening parameter (w) defining the range separated HSE type hybrid functional is systematically studied for a series of seven metal oxides: TiO 2 , ZrO 2 , CuO 2 , ZnO, MgO, SnO 2 , and SrTiO 3 . First, reliable band gap values were determined by comparing the optimal α reproducing the experiment with the inverse of the experimental dielectric constant. Then, the effect of the w in the HSE functional on the calculated band gap was explored in detail. Results evidence the existence of a virtually infinite number of combinations of the two parameters which are able to reproduce the experimental band gap, without a unique pair able to describe the full studied set of materials. Nevertheless, the results point out the possibility of describing the electronic structure of these materials through a functional including a screened HF exchange and an appropriate correlation contribution. © 2017 Wiley Periodicals, Inc. © 2017 Wiley Periodicals, Inc.

Development of novel therapies for MG: Studies in animal models.

PubMed

Souroujon, M C; Brenner, T; Fuchs, S

2010-08-01

Experimental myasthenia gravis (MG) in animals, and in particular experimental autoimmune MG in rodents, serves as excellent models to study possible novel therapeutic modalities for MG. The current treatments for MG are based on cholinesterase inhibitors, general immunosuppressants, and corticosteroids, broad immunomodulatory therapies such as plasma exchange or intravenous immunoglobulins (IVIGs), and thymectomy for selected patients. This stresses the need for immunotherapies that would specifically or preferentially suppress the undesirable autoimmune response without widely affecting the entire immune system as most available treatments do. The available animal models for MG enable to perform preclinical studies in which novel therapeutic approaches can be tested. In this review, we describe the different therapeutic approaches that were so far tested in experimental models of MG and discuss their underlying mechanisms of action. These include antigen - acetylcholine receptor (AChR)-dependent treatments aimed at specifically abrogating the humoral and cellular anti-AChR responses as well as immunomodulatory approaches that could be used either alone or in conjunction with antigen-specific treatments or alternatively serve as steroid sparing agents. The antigen-specific treatments are based on fragments or peptides derived from the acetylcholine receptor (AChR) that would theoretically deviate the anti-AChR autoimmune response away from the muscle target or on ways to target AChR-specific T- and B- cell responses or antibodies. The immunomodulatory modalities include cell-based and non-cell-based ways to affect or manipulate key players in the autoimmune process such as regulatory T cells, dendritic cells, cytokine networks, and chemokine and costimulatory signaling as well as complement pathways. We also describe approaches that attempt to affect the cholinergic balance, which is impaired at the neuromuscular junction. In addition to enabling to test the feasibility of novel approaches, experimental MG enables to perform analyses of existing treatment modalities, which cannot be performed in human MG patients. These include studies on the mode of action of various immunosuppressants and on IVIGs. Hopefully, the vast repertoire of therapeutic approaches that are studied in experimental models of MG will pave the way to clinical studies that will eventually improve the management of MG.

Negative thermal expansion and anomalies of heat capacity of LuB 50 at low temperatures

DOE Office of Scientific and Technical Information (OSTI.GOV)

Novikov, V. V.; Zhemoedov, N. A.; Matovnikov, A. V.

2015-07-20

Heat capacity and thermal expansion of LuB 50 boride were experimentally studied in the 2–300 K temperature range. The data reveal an anomalous contribution to the heat capacity at low temperatures. The value of this contribution is proportional to the first degree of temperature. It was identified that this anomaly in heat capacity is caused by the effect of disorder in the LuB 50 crystalline structure and it can be described in the soft atomic potential model (SAP). The parameters of the approximation were determined. The temperature dependence of LuB 50 heat capacity in the whole temperature range was approximatedmore » by the sum of SAP contribution, Debye and two Einstein components. The parameters of SAP contribution for LuB 50 were compared to the corresponding values for LuB 66, which was studied earlier. Negative thermal expansion at low temperatures was experimentally observed for LuB 50. The analysis of the experimental temperature dependence for the Gruneisen parameter of LuB 50 suggested that the low-frequency oscillations, described in SAP mode, are responsible for the negative thermal expansion. As a result, the glasslike character of the behavior of LuB 50 thermal characteristics at low temperatures was confirmed.« less

Three-dimensional simulations of nanopowder compaction processes by granular dynamics method.

PubMed

Boltachev, G Sh; Lukyashin, K E; Shitov, V A; Volkov, N B

2013-07-01

In order to describe and to study the processes of cold compaction within the discrete element method a three-dimensional model of nanosized powder is developed. The elastic forces of repulsion, the tangential forces of "friction" (Cattaneo-Mindlin), and the dispersion forces of attraction (van der Waals-Hamaker), as well as the formation and destruction of hard bonds between the individual particles are taken into account. The monosized powders with the size of particles in the range 10-40 nm are simulated. The simulation results are compared to the experimental data of the alumina nanopowders compaction. It is shown that the model allows us to reproduce experimental data reliably and, in particular, describes the size effect in the compaction processes. A number of different external loading conditions is used in order to perform the theoretical and experimental researches. The uniaxial compaction (the closed-die compaction), the biaxial (radial) compaction, and the isotropic compaction (the cold isostatic pressing) are studied. The real and computed results are in a good agreement with each other. They reveal a weak sensitivity of the oxide nanopowders to the loading condition (compaction geometry). The application of the continuum theory of the plastically hardening porous body, which is usually used for the description of powders, is discussed.

Experimental study of low-temperature plasma of electrical discharges with liquid electrodes

NASA Astrophysics Data System (ADS)

Zheltukhin, Viktor; Gaisin, Almaz

2016-09-01

Results of the experimental research of discharge between the liquid jet cathode (LJC) and the metal anode are presented. The discharge was studied over the voltage range U = 100 - 600 V, discharge current range I = 0 . 1 - 0 . 25 A, external pressure range P =105 Pa, discharge power Pd = 10 - 150 W. We used the techniques of infrared thermography and spectral measurements. Schlieren's photography is applied for describing the processes in liquid and gas phase. Results of the experimental researches of discharge current-voltage characteristic (CVC), the surface temperature distribution both on the LJC and the metal anode, a spectral measurements are showed. Effects of action both of breakdown and discharge on the jet flow as well as on the air flow near the discharge are described. It is found that the discharge CVC has an ascending behavior due to increase of plasma current density. The discharge is generated on the borders between the LJC and the metal anode as well as along the LJC misshaping this one. It is established that both the convection streams and an electrolyte drops are formed during the discharge burn. It is found that the discharge temperature in the vicinity of electrode surface reaches T 348 K. The work was funded by RFBR, according to the research projects No.,14-01-0755.

Three-dimensional simulations of nanopowder compaction processes by granular dynamics method

NASA Astrophysics Data System (ADS)

Boltachev, G. Sh.; Lukyashin, K. E.; Shitov, V. A.; Volkov, N. B.

2013-07-01

In order to describe and to study the processes of cold compaction within the discrete element method a three-dimensional model of nanosized powder is developed. The elastic forces of repulsion, the tangential forces of “friction” (Cattaneo-Mindlin), and the dispersion forces of attraction (van der Waals-Hamaker), as well as the formation and destruction of hard bonds between the individual particles are taken into account. The monosized powders with the size of particles in the range 10-40 nm are simulated. The simulation results are compared to the experimental data of the alumina nanopowders compaction. It is shown that the model allows us to reproduce experimental data reliably and, in particular, describes the size effect in the compaction processes. A number of different external loading conditions is used in order to perform the theoretical and experimental researches. The uniaxial compaction (the closed-die compaction), the biaxial (radial) compaction, and the isotropic compaction (the cold isostatic pressing) are studied. The real and computed results are in a good agreement with each other. They reveal a weak sensitivity of the oxide nanopowders to the loading condition (compaction geometry). The application of the continuum theory of the plastically hardening porous body, which is usually used for the description of powders, is discussed.

Experimental Study of Exclusive H2(e,e'p)n Reaction Mechanisms at High Q2

NASA Astrophysics Data System (ADS)

Egiyan, K. S.; Asryan, G.; Gevorgyan, N.; Griffioen, K. A.; Laget, J. M.; Kuhn, S. E.; Adams, G.; Amaryan, M. J.; Ambrozewicz, P.; Anghinolfi, M.; Audit, G.; Avakian, H.; Bagdasaryan, H.; Baillie, N.; Ball, J. P.; Baltzell, N. A.; Barrow, S.; Batourine, V.; Battaglieri, M.; Bedlinskiy, I.; Bektasoglu, M.; Bellis, M.; Benmouna, N.; Berman, B. L.; Biselli, A. S.; Blaszczyk, L.; Bouchigny, S.; Boiarinov, S.; Bradford, R.; Branford, D.; Briscoe, W. J.; Brooks, W. K.; Bültmann, S.; Burkert, V. D.; Butuceanu, C.; Calarco, J. R.; Careccia, S. L.; Carman, D. S.; Cazes, A.; Chen, S.; Cole, P. L.; Collins, P.; Coltharp, P.; Cords, D.; Corvisiero, P.; Crabb, D.; Crede, V.; Cummings, J. P.; Dashyan, N.; de Masi, R.; de Vita, R.; de Sanctis, E.; Degtyarenko, P. V.; Denizli, H.; Dennis, L.; Deur, A.; Dharmawardane, K. V.; Dickson, R.; Djalali, C.; Dodge, G. E.; Donnelly, J.; Doughty, D.; Dugger, M.; Dytman, S.; Dzyubak, O. P.; Egiyan, H.; El Fassi, L.; Elouadrhiri, L.; Eugenio, P.; Fatemi, R.; Fedotov, G.; Feldman, G.; Feuerbach, R. J.; Fersch, R.; Garçon, M.; Gavalian, G.; Gilfoyle, G. P.; Giovanetti, K. L.; Girod, F. X.; Goetz, J. T.; Gonenc, A.; Gordon, C. I. O.; Gothe, R. W.; Guidal, M.; Guillo, M.; Guler, N.; Guo, L.; Gyurjyan, V.; Hadjidakis, C.; Hafidi, K.; Hakobyan, H.; Hakobyan, R. S.; Hanretty, C.; Hardie, J.; Hersman, F. W.; Hicks, K.; Hleiqawi, I.; Holtrop, M.; Hyde-Wright, C. E.; Ilieva, Y.; Ireland, D. G.; Ishkhanov, B. S.; Isupov, E. L.; Ito, M. M.; Jenkins, D.; Jo, H. S.; Joo, K.; Juengst, H. G.; Kalantarians, N.; Kellie, J. D.; Khandaker, M.; Kim, W.; Klein, A.; Klein, F. J.; Klimenko, A. V.; Kossov, M.; Krahn, Z.; Kramer, L. H.; Kubarovsky, V.; Kuhn, J.; Kuleshov, S. V.; Lachniet, J.; Langheinrich, J.; Lawrence, D.; Li, Ji; Livingston, K.; Lu, H. Y.; MacCormick, M.; Marchand, C.; Markov, N.; Mattione, P.; McAleer, S.; McKinnon, B.; McNabb, J. W. C.; Mecking, B. A.; Mehrabyan, S.; Melone, J. J.; Mestayer, M. D.; Meyer, C. A.; Mibe, T.; Mikhailov, K.; Minehart, R.; Mirazita, M.; Miskimen, R.; Mokeev, V.; Moriya, K.; Morrow, S. A.; Moteabbed, M.; Mueller, J.; Munevar, E.; Mutchler, G. S.; Nadel-Turonski, P.; Nasseripour, R.; Niccolai, S.; Niculescu, G.; Niculescu, I.; Niczyporuk, B. B.; Niroula, M. R.; Niyazov, R. A.; Nozar, M.; O'Rielly, G. V.; Osipenko, M.; Ostrovidov, A. I.; Park, K.; Pasyuk, E.; Paterson, C.; Anefalos Pereira, S.; Pierce, J.; Pivnyuk, N.; Pocanic, D.; Pogorelko, O.; Pozdniakov, S.; Preedom, B. M.; Price, J. W.; Prok, Y.; Protopopescu, D.; Raue, B. A.; Riccardi, G.; Ricco, G.; Ripani, M.; Ritchie, B. G.; Ronchetti, F.; Rosner, G.; Rossi, P.; Sabatié, F.; Salamanca, J.; Salgado, C.; Santoro, J. P.; Sapunenko, V.; Schumacher, R. A.; Serov, V. S.; Sharabian, Y. G.; Shvedunov, N. V.; Skabelin, A. V.; Smith, E. S.; Smith, L. C.; Sober, D. I.; Sokhan, D.; Stavinsky, A.; Stepanyan, S. S.; Stepanyan, S.; Stokes, B. E.; Stoler, P.; Strauch, S.; Taiuti, M.; Tedeschi, D. J.; Thoma, U.; Tkabladze, A.; Tkachenko, S.; Todor, L.; Tur, C.; Ungaro, M.; Vineyard, M. F.; Vlassov, A. V.; Watts, D. P.; Weinstein, L. B.; Weygand, D. P.; Williams, M.; Wolin, E.; Wood, M. H.; Yegneswaran, A.; Zana, L.; Zhang, J.; Zhao, B.; Zhao, Z. W.

2007-06-01

The reaction H2(e,e'p)n has been studied with full kinematic coverage for photon virtuality 1.75

A three-level advanced static VAr compensator

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ekanayake, J.B.; Jenkins, N.

1996-01-01

An Advanced Static VAr Compensator (ASVC) employing a three level inverter has been investigated for three phase applications. The paper describes the operating principles of the ASVC using an elementary single phase ASVC circuit. The construction of a hardware model of the three phase, three level ASVC is then presented. The performance of the ASVC is obtained from an experimental study carried out on this laboratory model. The use of the selective harmonic elimination modulation (SHEM) technique to minimize harmonics is explored. Experimental studies have been carried out to determine the speed of response of the scheme by controlling itmore » in a closed loop.« less

Atmosphere behavior in gas-closed mouse-algal systems - An experimental and modelling study

NASA Technical Reports Server (NTRS)

Averner, M. M.; Moore, B., III; Bartholomew, I.; Wharton, R.

1984-01-01

A NASA-sponsored research program initiated using mathematical modelling and laboratory experimentation aimed at examining the gas-exchange characteristics of artificial animal/plant systems closed to the ambient atmosphere is studied. The development of control techniques and management strategies for maintaining the atmospheric levels of carbon dioxide and oxygen at physiological levels is considered. A mathematical model simulating the behavior of a gas-closed mouse-algal system under varying environmental conditions is described. To verify and validate the model simulations, an analytical system with which algal growth and gas exchange characteristics can be manipulated and measured is designed, fabricated, and tested. The preliminary results are presented.

Thermogravity system designed for use in dispersion strengthening studies

NASA Technical Reports Server (NTRS)

Herbell, T. P.

1972-01-01

A thermogravimetry system designed to study the reduction of oxides in metal and alloy powders to be used in dispersion strengthened materials is described. The apparatus was devised for use at high temperatures with controlled atmospheres. Experimental weight change and moisture evolution results for the thermal decomposition of calcium oxalate monohydrate in dry helium, and experimental weight change results for the reduction of nickel oxide in dry hydrogen and hydrogen containing 15,000 PPM water vapor are presented. The system is currently being successfully applied to the evaluation of the reduction characteristics and the removal of impurities from metals and alloys to be used for dispersion strengthening.

Thermogravimetry system designed for use in dispersion strengthening studies.

NASA Technical Reports Server (NTRS)

Herbell, T. P.

1972-01-01

A thermogravimetry system, designed to study the reduction of oxides in metal and alloy powders to be used in dispersion strengthened materials, is described. The apparatus was devised for use at high temperatures with controlled atmospheres. Experimental weight change and moisture evolution results for the thermal decomposition of calcium oxalate monohydrate in dry helium, and experimental weight change results for the reduction of nickel oxide in dry hydrogen and hydrogen containing 15,000 p.p.m. water vapor are presented. The system is currently being successfully applied to the evaluation of the reduction characteristics and the removal of impurities from metals and alloys to be used for dispersion strengthening.

Kinetics of formation and dissociation of gas hydrates

NASA Astrophysics Data System (ADS)

Manakov, A. Yu; Penkov, N. V.; Rodionova, T. V.; Nesterov, A. N.; Fesenko, E. E., Jr.

2017-09-01

The review covers a wide range of issues related to the nucleation, growth and dissociation of gas hydrates. The attention is focused on publications of the last 10-15 years. Along with the mathematical models used to describe these processes, the results of relevant experimental studies are surveyed. Particular sections are devoted to the gas hydrate self-preservation effect, the water memory effect in the hydrate formation, development of catalysts for hydrate formation and the effect of substances dissolved in the aqueous phase on the formation of hydrates. The main experimental techniques used to study gas hydrates are briefly considered. The bibliography includes 230 references.

Experimental and numerical study on the strength of all-ceramic crowns

NASA Astrophysics Data System (ADS)

Lu, Chenglin; Zhang, Xiuyin; Zhang, Dongsheng

2008-11-01

Two types of sectioned tooth-like ceramic crowns (IPS Empress 2) were prepared along lingual-facial direction and the fracture process of crowns under contact load was directly monitored with the use of imaging system. The displacement filed resulted from digital image correlation indicate that the fracture mode of real crown is more complicated while the flat crown has the same rupture mode as described by other investigators. Meanwhile numerical simulation was also carried out to support the experiments. Stress distributions in individual layer and interface were presented. Results indicate that the presented experimental and numerical methods are efficient in studying the fracture mechanism of all-ceramic crowns.

Dynamic crystallization study of barred olivine chondrules

NASA Technical Reports Server (NTRS)

Lofgren, Gary; Lanier, A. B.

1990-01-01

The 'classic' barred olivine (BO) texture was defined by Donaldson (1976) as a single-plate dendrite which shares the entire chondrule with the remaining glass or subsequent crystallization products. This paper describes experiments in which BO textures were produced experimentally from two starting compositions: one modeled after the average BO chondrule composition in L-chondrites determined by Weisberg (1987), and the other after an olivine-rich composition (CH-1) studied by Lofgren (1989). It is shown that most of the textural features observed in natural BO chondrules are replicated in the experimentally produced chondrules. Several new constraints on models for the chondrule-forming process are proposed.

Dog EEG for wake-promotion studies.

PubMed

Parmentier, Régis; Bricout, Denis; Brousseau, Emmanuel; Giboulot, Thierry

2006-10-01

Described in this unit is a protocol for investigating the wake-promoting activity of new chemical entities (NCEs) in dog. The experimental approach is based on scoring of sleep/wake stages in animals implanted with a telemetry device for recording EMG and cortical EEG signals. A major advantage of this procedure is that it is conducted in nontethered animals, limiting possible bias and complications encountered with conventional recording systems. In this procedure, polygraphic recording is conducted using four implanted beagles. Results of studies with modafinil, a wake-promoting agent, are described to demonstrate the utility of this test procedure.

Analysis of bacterial migration; 1: Numerical solution of balance equation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Frymier, P.D.; Ford, R.M.; Cummings, P.T.

1994-04-01

Chemotaxis describes the ability of motile bacteria to bias their motion in the direction of increasing gradients of chemicals, usually energy sources, known as attractants. In experimental studies of the migration of chemotactic bacteria, 1-D phenomenological cell balance equations have been used to quantitatively analyze experimental observations. While attractive for their simplicity and the ease of solution, they are limited in the strict mathematical sense to the situation in which individual bacteria are confined to motion in one dimension and respond to attractant gradients in one dimension only. Recently, Ford and Cummings (1992) reduced the general 3-D cell balance equationmore » of Alt (1980) to obtain an equation describing the migration of a bacterial population in response to a 1-D attractant gradient. Solutions of this equation for single gradients of attractants are compared to those of 1-D balance equations, results from cellular dynamics simulations, and experimental data from the authors' laboratory for E. coli responding to [alpha]-methylaspartate. The authors also investigate two aspects of the experimentally derived expression for the tumbling probability: the effect of different models for the down-gradient swimming behavior of the bacteria and the validity of ignoring the temporal derivative of the attractant concentration.« less

Design and Experimental Study on Spinning Solid Rocket Motor

NASA Astrophysics Data System (ADS)

Xue, Heng; Jiang, Chunlan; Wang, Zaicheng

The study on spinning solid rocket motor (SRM) which used as power plant of twice throwing structure of aerial submunition was introduced. This kind of SRM which with the structure of tangential multi-nozzle consists of a combustion chamber, propellant charge, 4 tangential nozzles, ignition device, etc. Grain design, structure design and prediction of interior ballistic performance were described, and problem which need mainly considered in design were analyzed comprehensively. Finally, in order to research working performance of the SRM, measure pressure-time curve and its speed, static test and dynamic test were conducted respectively. And then calculated values and experimental data were compared and analyzed. The results indicate that the designed motor operates normally, and the stable performance of interior ballistic meet demands. And experimental results have the guidance meaning for the pre-research design of SRM.

A Practical Engineering Approach to Predicting Fatigue Crack Growth in Riveted Lap Joints

NASA Technical Reports Server (NTRS)

Harris, Charles E.; Piascik, Robert S.; Newman, James C., Jr.

1999-01-01

An extensive experimental database has been assembled from very detailed teardown examinations of fatigue cracks found in rivet holes of fuselage structural components. Based on this experimental database, a comprehensive analysis methodology was developed to predict the onset of widespread fatigue damage in lap joints of fuselage structure. Several computer codes were developed with specialized capabilities to conduct the various analyses that make up the comprehensive methodology. Over the past several years, the authors have interrogated various aspects of the analysis methods to determine the degree of computational rigor required to produce numerical predictions with acceptable engineering accuracy. This study led to the formulation of a practical engineering approach to predicting fatigue crack growth in riveted lap joints. This paper describes the practical engineering approach and compares predictions with the results from several experimental studies.

A Practical Engineering Approach to Predicting Fatigue Crack Growth in Riveted Lap Joints

NASA Technical Reports Server (NTRS)

Harris, C. E.; Piascik, R. S.; Newman, J. C., Jr.

2000-01-01

An extensive experimental database has been assembled from very detailed teardown examinations of fatigue cracks found in rivet holes of fuselage structural components. Based on this experimental database, a comprehensive analysis methodology was developed to predict the onset of widespread fatigue damage in lap joints of fuselage structure. Several computer codes were developed with specialized capabilities to conduct the various analyses that make up the comprehensive methodology. Over the past several years, the authors have interrogated various aspects of the analysis methods to determine the degree of computational rigor required to produce numerical predictions with acceptable engineering accuracy. This study led to the formulation of a practical engineering approach to predicting fatigue crack growth in riveted lap joints. This paper describes the practical engineering approach and compares predictions with the results from several experimental studies.

Study and characterization of a MEMS micromirror device

NASA Astrophysics Data System (ADS)

Furlong, Cosme; Pryputniewicz, Ryszard J.

2004-08-01

In this paper, advances in our study and characterization of a MEMS micromirror device are presented. The micromirror device, of 510 mm characteristic length, operates in a dynamic mode with a maximum displacement on the order of 10 mm along its principal optical axis and oscillation frequencies of up to 1.3 kHz. Developments are carried on by analytical, computational, and experimental methods. Analytical and computational nonlinear geometrical models are developed in order to determine the optimal loading-displacement operational characteristics of the micromirror. Due to the operational mode of the micromirror, the experimental characterization of its loading-displacement transfer function requires utilization of advanced optical metrology methods. Optoelectronic holography (OEH) methodologies based on multiple wavelengths that we are developing to perform such characterization are described. It is shown that the analytical, computational, and experimental approach is effective in our developments.

Development of an automated experimental setup for the study of ionic-exchange kinetics. Application to the ionic adsorption, equilibrium attainment and dissolution of apatite compounds.

PubMed

Thomann, J M; Gasser, P; Bres, E F; Voegel, J C; Gramain, P

1990-02-01

An ion-selective electrode and microcomputer-based experimental setup for the study of ionic-exchange kinetics between a powdered solid and the solution is described. The equipment is composed of easily available commercial devices and a data acquisition and regularization computer program is presented. The system, especially developed to investigate the ionic adsorption, equilibrium attainment and dissolution of hard mineralized tissues, provides good reliable results by taking into account the volume changes of the reacting solution and the electrode behaviour under different experimental conditions, and by avoiding carbonation of the solution. A second computer program, using the regularized data and the experimental parameters, calculates the quantities of protons consumed and calcium released in the case of equilibrium attainment and dissolution of apatite-like compounds. Finally, typical examples of ion-exchange and dissolution kinetics under constant pH of enamel and synthetic hydroxyapatite are examined.

Research designs for studies evaluating the effectiveness of change and improvement strategies.

PubMed

Eccles, M; Grimshaw, J; Campbell, M; Ramsay, C

2003-02-01

The methods of evaluating change and improvement strategies are not well described. The design and conduct of a range of experimental and non-experimental quantitative designs are considered. Such study designs should usually be used in a context where they build on appropriate theoretical, qualitative and modelling work, particularly in the development of appropriate interventions. A range of experimental designs are discussed including single and multiple arm randomised controlled trials and the use of more complex factorial and block designs. The impact of randomisation at both group and individual levels and three non-experimental designs (uncontrolled before and after, controlled before and after, and time series analysis) are also considered. The design chosen will reflect both the needs (and resources) in any particular circumstances and also the purpose of the evaluation. The general principle underlying the choice of evaluative design is, however, simple-those conducting such evaluations should use the most robust design possible to minimise bias and maximise generalisability.

A More Rigorous Quasi-Experimental Alternative to the One-Group Pretest-Posttest Design.

ERIC Educational Resources Information Center

Johnson, Craig W.

1986-01-01

A simple quasi-experimental design is described which may have utility in a variety of applied and laboratory research settings where ordinarily the one-group pretest-posttest pre-experimental design might otherwise be the procedure of choice. The design approaches the internal validity of true experimental designs while optimizing external…

Snow cover in the Siberian forest-steppe

NASA Technical Reports Server (NTRS)

Zykov, I. V.

1985-01-01

A study is made of the snow cover on an experimental agricultural station in Mariinsk in the winter of 1945 to 1946. Conditions of snow cover formation, and types and indicators of snow cover are discussed. Snow cover structure and conditions and nature of thawing are described.

Principles and Techniques of Radiation Chemistry.

ERIC Educational Resources Information Center

Dorfman, Leon M.

1981-01-01

Discusses the physical processes involved in the deposition of energy from ionizing radiation in the absorber system. Identifies principles relevant to these processes which are responsible for ionization and excitation of the components of the absorber system. Briefly describes some experimental techniques in use in radiation chemical studies.…

Effects of Logo Instruction on Cognitive Style.

ERIC Educational Resources Information Center

Cathcart, W. George

1990-01-01

Describes study that was conducted with fifth graders to investigate the effects of Logo instruction on three measures of cognitive style: divergent thinking, field dependence/independence, and impulsivity/reflectivity. Treatments of the experimental and control groups are explained, and results of pretests and posttests are analyzed. (11…

Interdisciplinary Aspects of Learning: Physics and Psychology

ERIC Educational Resources Information Center

Oleg, Yavoruk

2015-01-01

The article deals with interdisciplinary aspects of learning in the case of physics and psychology. It describes the lab-based academic course focused on: observation and experimentation; discovery of new scientific facts; measurement; identification of errors; the study of psychological characteristics of people (time perception, the reaction…

Enzyme Activity Experiments Using a Simple Spectrophotometer

ERIC Educational Resources Information Center

Hurlbut, Jeffrey A.; And Others

1977-01-01

Experimental procedures for studying enzyme activity using a Spectronic 20 spectrophotometer are described. The experiments demonstrate the effect of pH, temperature, and inhibitors on enzyme activity and allow the determination of Km, Vmax, and Kcat. These procedures are designed for teaching large lower-level biochemistry classes. (MR)

Uranium transport in a crushed granodiorite: Experiments and reactive transport modeling

DOE PAGES

Dittrich, T. M.; Reimus, P. W.

2015-02-12

The primary objective of this study was to develop and demonstrate an experimental method to refine and better parameterize process models for reactive contaminant transport in aqueous subsurface environments and to reduce conservatism in such models without attempting to fully describe the geochemical system.

Self-Disclosure as an Exchange Process: Reinforcement Effects.

ERIC Educational Resources Information Center

Taylor, Dalmas A.

In association with an extensive examination of the disclosure literature, this paper describes two laboratory studies designed to yield information regarding the effects of reinforcement on self-disclosing behaviors in an exchange process. In one series, the experimenters manipulated the patterns of personal reward/cost experiences, hypothesizing…

An Experiment in Teaching Human Ethology

ERIC Educational Resources Information Center

Barnett, S. A.

1977-01-01

Students of ethology are often confused about the validity of arguments based on comparisons of animal and human behavior. The problem can be dealt with purely theoretically or through observational or experimental studies of human behavior. Some results of using these two methods are described and discussed. (Author/MA)

Dusty plasma in a glow discharge in helium in temperature range of 5–300 K

DOE Office of Scientific and Technical Information (OSTI.GOV)

Samoilov, I. S.; Baev, V. P.; Timofeev, A. V., E-mail: timofeevalvl@gmail.com

2017-03-15

Dusty plasma structures in glow discharge in helium in the temperature range of 5–300 K are investigated experimentally. We have described the experimental setup that makes it possible to continuously vary the temperature regime. The method for experimental data processing has been described. We have measured interparticle distances in the temperature range of 9–295 K and compared them with the Debye radius. We indicate the ranges of variations in experimental parameters in which plasma–dust structures are formed and various types of their behavior are manifested (rotation, vibrations of structures, formation of vertical linear chains, etc.). The applicability of the Yukawamore » potential to the description of the structural properties of a dusty plasma in the experimental conditions is discussed.« less

The use of a helicopter mounted ranging scatterometer for estimation of extinction and backscattering properties of forest canopies-I: Experimental approach and calibration

NASA Technical Reports Server (NTRS)

Pitts, David E.; Badhwar, Gautam D.; Reyna, Eddie; Ulaby, Fawwaz T.; Brunfeldt, David R.

1988-01-01

A helicopter-borne C-band scatterometer with the capability of collecting the backscattered power as a function of range is described. This instrument was repeatedly flown from May to September 1984 to study the microwave properties of forest canopies of aspen and black spruce in the Superior National Forest in Minnesota. The characteristics of the instrument, its calibration, the data collection, and preprocessing, are described.

Chiral behaviour of the wave functions for three wave guides in the vicinity of an exceptional point of third order

NASA Astrophysics Data System (ADS)

Heiss, Walter Dieter; Wunner, Günter

2017-12-01

A matrix model that has been used to describe essential features of a parity-time symmetric set-up of three coupled wave guides is investigated. The emphasis of the study lies on the occurrence of an exceptional point of third order. It is demonstrated that the eigenfunctions in close vicinity of the exceptional point have a distinctive chiral behaviour. Using data describing realistic situations it is argued that such chiral behaviour can be tested experimentally.

Applications of Advanced Experimental Methods to Visual Technology Research Simulator Studies: Supplemental Techniques.

DTIC Science & Technology

1981-01-01

straight line. Those that are larger than might be expected by chance will deviate i.oticeably from the line. Wilk and Gnanadesikan (1964; also see Roy... Gnanadesikan , and Srivasta, 1971, Chapter VIII; also see Simon, 1977a, pp 151-158 for a general description of the procedure) describe how to use a...by Wilk and Gnanadesikan is rather involved and is explained in matrix algebra terms, it is described b-low along with an example to facilitate its

Aerodynamics of the EXPERT Re-Entry Ballistic Vehicle

NASA Astrophysics Data System (ADS)

Kharitonov, A. M.; Adamov, N. P.; Mazhul, I. I.; Vasenyov, L. G.; Zvegintsev, V. I.; Muylaert, J. M.

2009-01-01

Since 2002 till now, experimental studies of the EXPERT reentry capsule have been performed in ITAM SB RAS wind tunnels. These studies have been performed in consecutive ISTC project No. 2109, 3151, and currently ongoing project No. 3550. The results of earlier studies in ITAM wind tunnels can be found in [1-4]. The present paper describes new data obtained for the EXPERT model.

Mixing fuel particles for space combustion research using acoustics

NASA Technical Reports Server (NTRS)

Burns, Robert J.; Johnson, Jerome A.; Klimek, Robert B.

1988-01-01

Part of the microgravity science to be conducted aboard the Shuttle (STS) involves combustion using solids, particles, and liquid droplets. The central experimental facts needed for characterization of premixed quiescent particle cloud flames cannot be adequately established by normal gravity studies alone. The experimental results to date of acoustically mixing a prototypical particulate, lycopodium, in a 5 cm diameter by 75 cm long flame tube aboard a Learjet aircraft flying a 20 sec low gravity trajectory are described. Photographic and light detector instrumentation combine to measure and characterize particle cloud uniformity.

Mixing fuel particles for space combustion research using acoustics

NASA Technical Reports Server (NTRS)

Burns, Robert J.; Johnson, Jerome A.; Klimek, Robert B.

1988-01-01

Part of the microgravity science to be conducted aboard the Shuttle (STS) involves combustion using solids, particles, and liquid droplets. The central experimental facts needed for characterization of premixed quiescent particle cloud flames cannot be adequately established by normal gravity studies alone. The experimental results to date of acoustically mixing a prototypical particulate, lycopodium, in a 5 cm diameter by 75 cm long flame tube aboard a Learjet aircraft flying a 20-sec low-gravity trajectory are described. Photographic and light detector instrumentation combine to measure and characterize particle cloud uniformity.

Design and development of radioactive xenon gas purification and analysis system based on molecular sieves.

PubMed

Sabzian, M; Nasrabadi, M N; Haji-Hosseini, M

2018-10-01

The dynamic adsorption of xenon on molecular sieve packed columns was investigated. The modified Wheeler-Jonas equation was used to describe adsorption parameters such as adsorption capacity and adsorption rate coefficient. Different experimental conditions were accomplished to study their effects and to touch appropriate adsorbing circumstances. Respectable consistency was reached between experimental and modeled values. A purification and analysis setup was developed for radioactive xenon gas determination. Standard sample analysis results approved acceptable quantification accuracy. Copyright © 2018. Published by Elsevier Ltd.

Predator-prey Encounter Rates in Turbulent Environments: Consequences of Inertia Effects and Finite Sizes

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pecseli, H. L.; Trulsen, J.

2009-10-08

Experimental as well as theoretical studies have demonstrated that turbulence can play an important role for the biosphere in marine environments, in particular also by affecting prey-predator encounter rates. Reference models for the encounter rates rely on simplifying assumptions of predators and prey being described as point particles moving passively with the local flow velocity. Based on simple arguments that can be tested experimentally we propose corrections for the standard expression for the encounter rates, where now finite sizes and Stokes drag effects are included.

Quantitative weaknesses of the Marcus-Hush theory of electrode kinetics revealed by Reverse Scan Square Wave Voltammetry: The reduction of 2-methyl-2-nitropropane at mercury microelectrodes

NASA Astrophysics Data System (ADS)

Laborda, Eduardo; Wang, Yijun; Henstridge, Martin C.; Martínez-Ortiz, Francisco; Molina, Angela; Compton, Richard G.

2011-08-01

The Marcus-Hush and Butler-Volmer kinetic electrode models are compared experimentally by studying the reduction of 2-methyl-2-nitropropane in acetonitrile at mercury microelectrodes using Reverse Scan Square Wave Voltammetry. This technique is found to be very sensitive to the electrode kinetics and to permit critical comparison of the two models. The Butler-Volmer model satisfactorily fits the experimental data whereas Marcus-Hush does not quantitatively describe this redox system.

Coagulation of dust grains in the plasma of an RF discharge in argon

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mankelevich, Yu. A.; Olevanov, M. A.; Pal', A. F.

2009-03-15

Results are presented from experimental studies of coagulation of dust grains of different sizes injected into a low-temperature plasma of an RF discharge in argon. A theoretical model describing the formation of dust clusters in a low-temperature plasma is developed and applied to interpret the results of experiments on the coagulation of dust grains having large negative charges. The grain size at which coagulation under the given plasma conditions is possible is estimated using the developed theory. The theoretical results are compared with the experimental data.

Strain measurements in a rotary engine housing

NASA Technical Reports Server (NTRS)

Lee, C. M.; Bond, T. H.; Addy, H. E.; Chun, K. S.; Lu, C. Y.

1989-01-01

The development of structural design tools for Rotary Combustion Engines (RCE) using Finite Element Modeling (FEM) requires knowledge about the response of engine materials to various service conditions. This paper describes experimental work that studied housing deformation as a result of thermal, pressure and mechanical loads. The measurement of thermal loads, clamping pressure, and deformation was accomplished by use of high-temperature strain gauges, thermocouples, and a high speed data acquisition system. FEM models for heat transfer stress analysis of the rotor housing will be verified and refined based on these experimental results.

The distribution of the scattered laser light in laser-plate-target coupling

NASA Astrophysics Data System (ADS)

Xiao-bo, Nie; Tie-qiang, Chang; Dong-xian, Lai; Shen-ye, Liu; Zhi-jian, Zheng

1997-04-01

Theoretical and experimental studies of the angular distributions of scattered laser light in laser-Au-plate-target coupling are reported. A simple model that describes three-dimensional plasmas and scattered laser light is presented. The approximate shape of critical density surface has been given and the three-dimensional laser ray tracing is applied in the model. The theoretical results of the model are consistent with the experimental data for the scattered laser light in the polar angle range of 25° to 145° from the laser beam.

Thawing of ice in porous space of building materials: Experimental monitoring and computational modelling

NASA Astrophysics Data System (ADS)

Kočí, Jan; Maděra, Jiří; Kočí, Václav; Hlaváčová, Zuzana; Černý, Robert

2017-11-01

A simple laboratory experiment for the determination of thermal response of a studied sample during thawing is described in the paper. The sample made of autoclaved aerated concrete was partially water saturated and frozen. Then, the temperature development during thawing was recorded, allowing to identify the time scale of the phase change process taking place inside the sample. The experimental data was then used in the inverse analysis, in order to find unknown parameters of the smoothed effective specific heat capacity model.

Experimental and numerical study of the British Experimental Rotor Programme blade

NASA Technical Reports Server (NTRS)

Brocklehurst, Alan; Duque, Earl P. N.

1990-01-01

Wind-tunnel tests on the British Experimental Rotor Programme (BERP) tip are described, and the results are compared with computational fluid dynamics (CFD) results. The test model was molded using the Lynx-BERP blade tooling to provide a semispan, cantilever wing comprising the outboard 30 percent of the rotor blade. The tests included both surface-pressure measurements and flow visualization to obtain detailed information of the flow over the BERP tip for a range of angles of attack. It was observed that, outboard of the notch, favorable pressure gradients exist which ensure attached flow, and that the tip vortex also remains stable to large angles of attack. On the rotor, these features yield a very gradual break in control loads when the retreating-blade limit is eventually reached. Computational and experimental results were generally found to be in good agreement.

Integrated Treatment to Achieve Functional Recovery for First-Episode Psychosis

PubMed Central

Valencia, Marcelo; Juarez, Francisco; Ortega, Hector

2012-01-01

This study describes an integrated treatment approach that was implemented to enhance functional recovery in first-episode psychotic patients. Patients were randomized to two treatment conditions: either to an integrated treatment approach: pharmacotherapy, psychosocial treatment, and psychoeducation (experimental group: N = 39) or to medication alone (control group: N = 34). Patients were evaluated at baseline and after one year of treatment. Functional recovery was assessed according to symptomatic and functional remission. At the end of treatment, experimental patients showed a 94.9% of symptomatic remission compared to 58.8% of the control group. Functional remission was 56.4% for the experimental group and 3.6% for the control group, while 56.4% of the experimental group met both symptomatic and functional remission criteria and were considered recovered compared to 2.9% of the control group. PMID:22970366

RESEARCH DESIGNS IN SPORTS PHYSICAL THERAPY

PubMed Central

2012-01-01

Research is designed to answer a question or to describe a phenomenon in a scientific process. Sports physical therapists must understand the different research methods, types, and designs in order to implement evidence‐based practice. The purpose of this article is to describe the most common research designs used in sports physical therapy research and practice. Both experimental and non‐experimental methods will be discussed. PMID:23091780

Automated detection of discourse segment and experimental types from the text of cancer pathway results sections.

PubMed

Burns, Gully A P C; Dasigi, Pradeep; de Waard, Anita; Hovy, Eduard H

2016-01-01

Automated machine-reading biocuration systems typically use sentence-by-sentence information extraction to construct meaning representations for use by curators. This does not directly reflect the typical discourse structure used by scientists to construct an argument from the experimental data available within a article, and is therefore less likely to correspond to representations typically used in biomedical informatics systems (let alone to the mental models that scientists have). In this study, we develop Natural Language Processing methods to locate, extract, and classify the individual passages of text from articles' Results sections that refer to experimental data. In our domain of interest (molecular biology studies of cancer signal transduction pathways), individual articles may contain as many as 30 small-scale individual experiments describing a variety of findings, upon which authors base their overall research conclusions. Our system automatically classifies discourse segments in these texts into seven categories (fact, hypothesis, problem, goal, method, result, implication) with an F-score of 0.68. These segments describe the essential building blocks of scientific discourse to (i) provide context for each experiment, (ii) report experimental details and (iii) explain the data's meaning in context. We evaluate our system on text passages from articles that were curated in molecular biology databases (the Pathway Logic Datum repository, the Molecular Interaction MINT and INTACT databases) linking individual experiments in articles to the type of assay used (coprecipitation, phosphorylation, translocation etc.). We use supervised machine learning techniques on text passages containing unambiguous references to experiments to obtain baseline F1 scores of 0.59 for MINT, 0.71 for INTACT and 0.63 for Pathway Logic. Although preliminary, these results support the notion that targeting information extraction methods to experimental results could provide accurate, automated methods for biocuration. We also suggest the need for finer-grained curation of experimental methods used when constructing molecular biology databases. © The Author(s) 2016. Published by Oxford University Press.

Head-mounted eye tracking: a new method to describe infant looking.

PubMed

Franchak, John M; Kretch, Kari S; Soska, Kasey C; Adolph, Karen E

2011-01-01

Despite hundreds of studies describing infants' visual exploration of experimental stimuli, researchers know little about where infants look during everyday interactions. The current study describes the first method for studying visual behavior during natural interactions in mobile infants. Six 14-month-old infants wore a head-mounted eye-tracker that recorded gaze during free play with mothers. Results revealed that infants' visual exploration is opportunistic and depends on the availability of information and the constraints of infants' own bodies. Looks to mothers' faces were rare following infant-directed utterances but more likely if mothers were sitting at infants' eye level. Gaze toward the destination of infants' hand movements was common during manual actions and crawling, but looks toward obstacles during leg movements were less frequent. © 2011 The Authors. Child Development © 2011 Society for Research in Child Development, Inc.

Unsteady-State Heat Transfer Involving a Phase Change: An Example of a 'Project-Oriented' Undergraduate Laboratory.

ERIC Educational Resources Information Center

Sundberg, Donald C.; Someshwar, Arun V.

1989-01-01

Describes the structure of an in-depth laboratory project chemical engineering. Provides modeling work to guide experimentation and experimental work on heat transfer analysis. Discusses the experimental results and evaluation of the project. (YP)

Progress on control experiments of flexible structures

NASA Technical Reports Server (NTRS)

Juang, Jer-Nan

1990-01-01

Progress at the NASA Langley Research Center in the area of control experiments for flexible structures is described. First the author presents the experimental results for a linear model which represents slewing maneuvers of a generic space station solar panel carried out to evaluate experimentally some control technologies. Then the status of the rotational/translational maneuvering experiment of a flexible steel panel carried by a translation cart is presented. Finally, experimental results of the NASA minimast testbed using velocity command stepper motors as reaction mass reactors are shown. All the test configurations are briefly described, including actuator and sensor, test setup, and test software. The status of some research activities oriented primarily to the experimental methods for control of flexible structures is presented.

QCL spectroscopy combined with the least squares method for substance analysis

NASA Astrophysics Data System (ADS)

Samsonov, D. A.; Tabalina, A. S.; Fufurin, I. L.

2017-11-01

The article briefly describes distinctive features of quantum cascade lasers (QCL). It also describes an experimental set-up for acquiring mid-infrared absorption spectra using QCL. The paper demonstrates experimental results in the form of normed spectra. We tested the application of the least squares method for spectrum analysis. We used this method for substance identification and extraction of concentration data. We compare the results with more common methods of absorption spectroscopy. Eventually, we prove the feasibility of using this simple method for quantitative and qualitative analysis of experimental data acquired with QCL.

Observation of prethermalization in long-range interacting spin chains

PubMed Central

Neyenhuis, Brian; Zhang, Jiehang; Hess, Paul W.; Smith, Jacob; Lee, Aaron C.; Richerme, Phil; Gong, Zhe-Xuan; Gorshkov, Alexey V.; Monroe, Christopher

2017-01-01

Although statistical mechanics describes thermal equilibrium states, these states may or may not emerge dynamically for a subsystem of an isolated quantum many-body system. For instance, quantum systems that are near-integrable usually fail to thermalize in an experimentally realistic time scale, and instead relax to quasi-stationary prethermal states that can be described by statistical mechanics, when approximately conserved quantities are included in a generalized Gibbs ensemble (GGE). We experimentally study the relaxation dynamics of a chain of up to 22 spins evolving under a long-range transverse-field Ising Hamiltonian following a sudden quench. For sufficiently long-range interactions, the system relaxes to a new type of prethermal state that retains a strong memory of the initial conditions. However, the prethermal state in this case cannot be described by a standard GGE; it rather arises from an emergent double-well potential felt by the spin excitations. This result shows that prethermalization occurs in a broader context than previously thought, and reveals new challenges for a generic understanding of the thermalization of quantum systems, particularly in the presence of long-range interactions. PMID:28875166

Studies of the Three-Nucleon System Dynamics in the Deuteron-Proton Breakup Reaction

NASA Astrophysics Data System (ADS)

Ciepał, I.; Kłos, B.; Stephan, E.; Kistryn, St.; Biegun, A.; Bodek, K.; Deltuva, A.; Epelbaum, E.; Eslami-Kalantari, M.; Fonseca, A. C.; Golak, J.; Jha, V.; Kalantar-Nayestanaki, N.; Kamada, H.; Khatri, G.; Kirillov, Da.; Kirillov, Di.; Kliczewski, St.; Kozela, A.; Kravcikova, M.; Machner, H.; Magiera, A.; Martinska, G.; Messchendorp, J.; Nogga, A.; Parol, W.; Ramazani-Moghaddam-Arani, A.; Roy, B. J.; Sakai, H.; Sekiguchi, K.; Sitnik, I.; Siudak, R.; Skibiński, R.; Sworst, R.; Urban, J.; Witała, H.; Zejma, J.

2014-03-01

One of the most important goals of modern nuclear physics is to contruct nuclear force model which properly describes the experimental data. To develop and test predictions of current models the breakup 1H(overrightarrow d, pp)n reaction was investigated experimentally at 100 and 130 MeV deuteron beam energies. Rich set of data for cross section, vector and tensor analyzing powers was obtained with the use of the SALAD and BINA detectors at KVI and Germanium Wall setup at FZ-Jülich. Results are compared with various theoretical approaches which describe the three-nucleon (3N) system dynamics. For correct description of the cross section data both, three-nucleon force (3NF) and Coulomb force, have to be included into calculations and influence of those ingredients is seizable at specific parts of the phase space. In case of the vector analyzing powers very low sensitivity to any effects beyond nucleon-nucleon interaction was found. At 130 MeV, the Axy data are not correctly described when 3NF models are included into calculations.

A distributed computing environment with support for constraint-based task scheduling and scientific experimentation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ahrens, J.P.; Shapiro, L.G.; Tanimoto, S.L.

1997-04-01

This paper describes a computing environment which supports computer-based scientific research work. Key features include support for automatic distributed scheduling and execution and computer-based scientific experimentation. A new flexible and extensible scheduling technique that is responsive to a user`s scheduling constraints, such as the ordering of program results and the specification of task assignments and processor utilization levels, is presented. An easy-to-use constraint language for specifying scheduling constraints, based on the relational database query language SQL, is described along with a search-based algorithm for fulfilling these constraints. A set of performance studies show that the environment can schedule and executemore » program graphs on a network of workstations as the user requests. A method for automatically generating computer-based scientific experiments is described. Experiments provide a concise method of specifying a large collection of parameterized program executions. The environment achieved significant speedups when executing experiments; for a large collection of scientific experiments an average speedup of 3.4 on an average of 5.5 scheduled processors was obtained.« less

Testing for Questionable Research Practices in a Meta-Analysis: An Example from Experimental Parapsychology

PubMed Central

Bierman, Dick J.; Spottiswoode, James P.; Bijl, Aron

2016-01-01

We describe a method of quantifying the effect of Questionable Research Practices (QRPs) on the results of meta-analyses. As an example we simulated a meta-analysis of a controversial telepathy protocol to assess the extent to which these experimental results could be explained by QRPs. Our simulations used the same numbers of studies and trials as the original meta-analysis and the frequencies with which various QRPs were applied in the simulated experiments were based on surveys of experimental psychologists. Results of both the meta-analysis and simulations were characterized by 4 metrics, two describing the trial and mean experiment hit rates (HR) of around 31%, where 25% is expected by chance, one the correlation between sample-size and hit-rate, and one the complete P-value distribution of the database. A genetic algorithm optimized the parameters describing the QRPs, and the fitness of the simulated meta-analysis was defined as the sum of the squares of Z-scores for the 4 metrics. Assuming no anomalous effect a good fit to the empirical meta-analysis was found only by using QRPs with unrealistic parameter-values. Restricting the parameter space to ranges observed in studies of QRP occurrence, under the untested assumption that parapsychologists use comparable QRPs, the fit to the published Ganzfeld meta-analysis with no anomalous effect was poor. We allowed for a real anomalous effect, be it unidentified QRPs or a paranormal effect, where the HR ranged from 25% (chance) to 31%. With an anomalous HR of 27% the fitness became F = 1.8 (p = 0.47 where F = 0 is a perfect fit). We conclude that the very significant probability cited by the Ganzfeld meta-analysis is likely inflated by QRPs, though results are still significant (p = 0.003) with QRPs. Our study demonstrates that quantitative simulations of QRPs can assess their impact. Since meta-analyses in general might be polluted by QRPs, this method has wide applicability outside the domain of experimental parapsychology. PMID:27144889

Nuffield Foundation 'Resources for Learning' Project. A Multi-Media Programmed Approach to Environmental Studies.

ERIC Educational Resources Information Center

Kefford, Colin W.

This description of a unit for teaching about the environment at the junior high level is an experimental study. The focus of the program is the integration of several media; films and tapes play a large role in the unit. Students perform a combination of classroom work, field work, and simulated exercises; assessment procedures are described.…

Effects of the Wisconsin Reading Design Comprehension Program on Reading Achievement and Self-Concept of Sixth Grade Students.

ERIC Educational Resources Information Center

Negley, Sandra Anne

The main purpose of this study was to determine and describe the effects of the comprehension component of the criterion-referenced reading program, Wisconsin Design for Reading Skills Development (WDRSD), on reading achievement and self-concept of sixth-grade students. Parametric techniques were employed in a quasi-experimental study involving 44…

Experimental study of fiber-glass plastic work pieces contour milling

NASA Astrophysics Data System (ADS)

Trushin, N. N.; Lisitsin, V. N.

2018-03-01

The article represents the results of study of cut and feed speed influence on wear of monolithic hard alloy end milling cutter during cutting of foiled fiber-glass plastic sheets, used for printed-circuit boards’ production. The peculiarities and problems of cutting layered materials are described. The most effective feed and cut speed values are determined by cutter wear analysis.

Applicability of implantable telemetry systems in cardiovascular research.

NASA Technical Reports Server (NTRS)

Krutz, R. W.; Rader, R. D.; Meehan, J. P.; Henry, J. P.

1971-01-01

This paper briefly describes the results of an experimental program undertaken to develop and apply implanted telemetry to cardiovascular research. Because of the role the kidney may play in essential hypertension, emphasis is placed on telemetry's applicability in the study of renal physiology. Consequently, the relationship between pressure, flow, and hydraulic impedance are stressed. Results of an exercise study are given.

Re-evaluation of cosmic ray cutoff terminology

NASA Technical Reports Server (NTRS)

Cooke, D. J.; Humble, J. E.; Shea, M. A.; Smart, D. F.; Lund, N.; Rasmussen, I. L.; Byrnak, B.; Goret, P.; Petrou, N.

1985-01-01

The study of cosmic ray access to locations inside the geomagnetic field has evolved in a manner that has led to some misunderstanding and misapplication of the terminology originally developed to describe particle access. This paper presents what is believed to be a useful set of definitions for cosmic ray cutoff terminology for use in theoretical and experimental cosmic ray studies.

Breakdown and invertebrate colonization of dead wood in wetland, upland, and river habitats

Treesearch

A Braccia; D Batzer

2010-01-01

Breakdown of woody debris in river and upland habitats as well as the interactions between wood and invertebrates have been well described. Studies of wood in wetlands are rare, and far less is known about breakdown and invertebrate use of wood in these transitional habitats. This study experimentally assessed breakdown and invertebrate colonization of wood in a...

An Experimental Study of the Effects of Employer-Sponsored Child Care Services on Selected Employee Behaviors. Executive Summary.

ERIC Educational Resources Information Center

Dawson, Ann Gilman; And Others

This executive summary describes a study conducted to determine whether different kinds of employer-supported child care services had differing effects on service users. Turnover and attendance data on 891 randomly selected female employees were gathered from 39 companies and hospitals offering on-site or off-site child care, information and…

Building Academic Skills in Context: Testing the Value of Enhanced Math Learning in CTE. Pilot Study

ERIC Educational Resources Information Center

Stone, James R., III; Alfeld, Corinne; Pearson, Donna; Lewis, Morgan V.; Jensen, Susan

2005-01-01

This report describes the conduct and outcomes of an experimental pilot study conducted in Spring 2004 to develop and test a model that aimed to enhance career and technical education (CTE) instruction with the mathematics already embedded in the curricula of six occupational areas. Although present in the CTE curriculum, math is largely implicit…

Remembrance of Things Future: Prospective Memory in Laboratory, Workplace, and Everyday Settings

NASA Technical Reports Server (NTRS)

Dismukes, R. Key

2010-01-01

In this review, oriented to the human factors community, I will summarize and provide a perspective on recent research and theory on prospective memory. This will not be an exhaustive review of literature, which is already available in two excellent recent books that provide a wealth of detail on the current state of experimental research (Kliegel, McCaniel, & Einstein, 2008; McDaniel & Einstein, 2007; also see Brandimonte, Einstein, & McDaniel, 1996, for a still relevant overview of the field as it was emerging). Rather, I will explore the limits of existing experimental paradigms and theory, Vvilich, in my opinion, fail to capture some critical aspects of performance outside the laboratory. I will also review the relatively few studies in workplace and everyday settings and will discuss several studies that attempt to bridge between the bulk of experimental studies and these few naturalistic studies. Finally, I will describe countermeasures that can reduce vulnerability to forgetting to perform intended tasks, and I will propose a research agenda that would extend existing experimental and theoretical approaches and would support human factors practitioners by generating information on a wide range of issues relevant to prospective memory performance in natural settings.

An Educational Laboratory for Digital Control and Rapid Prototyping of Power Electronic Circuits

ERIC Educational Resources Information Center

Choi, Sanghun; Saeedifard, M.

2012-01-01

This paper describes a new educational power electronics laboratory that was developed primarily to reinforce experimentally the fundamental concepts presented in a power electronics course. The developed laboratory combines theoretical design, simulation studies, digital control, fabrication, and verification of power-electronic circuits based on…

The Use of Paradoxes as an Instructional Strategy.

ERIC Educational Resources Information Center

Rastovac, John J.; Slavsky, David B.

1986-01-01

Describes a study in which paradoxes about seasons, hemispheres, and altitude were used to teach concepts in climatology. The misconceptions commonly held about the earth-sun distance relationship were used as an instructional strategy with an experimental group, which outgained the control group on an achievement test. (TW)

Pressed boride cathodes

NASA Technical Reports Server (NTRS)

Wolski, W.

1985-01-01

Results of experimental studies of emission cathodes made from lanthanum, yttrium, and gadolinium hexaborides are presented. Maximum thermal emission was obtained from lanthanum hexaboride electrodes. The hexaboride cathodes operated stably under conditions of large current density power draw, at high voltages and poor vacuum. A microtron electron gun with a lanthanum hexaboride cathode is described.

Stigma and Status: The Interrelation of Two Theoretical Perspectives

ERIC Educational Resources Information Center

Lucas, Jeffrey W.; Phelan, Jo C.

2012-01-01

This article explicates and distinguishes the processes that produce status orders and those that produce stigmatization. It describes an experimental study in which participants were assigned interaction partners before completing a task where they had opportunities to be influenced by the partners and opportunities to socially reject the…

Enhancing Students' Communication Skills through Treffinger Teaching Model

ERIC Educational Resources Information Center

Alhaddad, Idrus; Kusumah, Yaya S.; Sabandar, Jozua; Dahlan, Jarnawi A.

2015-01-01

This research aims to investigate, compare, and describe the achievement and enhancement of students' mathematical communication skills (MCS). It based on the prior mathematical knowledge (PMK) category (high, medium and low) by using Treffinger models (TM) and conventional learning (CL). This research is an experimental study with the population…

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lyon, J.F.; Grieger, G.; Rau, F.

The present status of stellarator experiments and recent progress in stellarator research (both experimental and theoretical) are reported by groups in the United States, the USSR, Japan, Australia, and the European Community (the Federal Republic of Germany and Spain). Experiments under construction and studies of large, next-generation stellarators are also described. 73 refs., 11 figs., 4 tabs.

Using Wikis for Learning and Knowledge Building: Results of an Experimental Study

ERIC Educational Resources Information Center

Kimmerle, Joachim; Moskaliuk, Johannes; Cress, Ulrike

2011-01-01

Computer-supported learning and knowledge building play an increasing role in online collaboration. This paper outlines some theories concerning the interplay between individual processes of learning and collaborative processes of knowledge building. In particular, it describes the co-evolution model that attempts to examine processes of learning…

Facilitating Family Group Inquiry at Science Museum Exhibits

ERIC Educational Resources Information Center

Gutwill, Joshua P.; Allen, Sue

2010-01-01

We describe a study of programs to deepen families' scientific inquiry practices in a science museum setting. The programs incorporated research-based learning principles from formal and informal educational environments. In a randomized experimental design, two versions of the programs, called "inquiry games," were compared to two control…

Publication Trends of Doctoral Students in Three Fields from 1965-1995.

ERIC Educational Resources Information Center

Lee, Wade M.

2000-01-01

Describes a study that investigated the publication rates of successful doctoral students in the fields of analytical chemistry, experimental psychology, and American literature. Data analysis, including linear regression analysis, revealed differences in publication rates and in solo authorship that mirrored differences between the fields as a…

Breeding bird communities

Treesearch

Vanessa L. Artman; Randy Dettmers

2003-01-01

Prescribed burning is being applied on an experimental basis to restore and maintain mixed-oak communities in southern Ohio. This chapter describes baseline conditions for the breeding bird community prior to prescribed burning. We surveyed breeding bird populations at four study areas using the territory-mapping method. We observed 35 bird species during the surveys....

The Treasure of the Humble: Lessons from Baker's Yeast

ERIC Educational Resources Information Center

Sitaraman, Ramakrishnan

2011-01-01

The study of model organisms is a powerful and proven experimental strategy for understanding biological processes. This paper describes an attempt to utilize advances in yeast molecular biology to enhance student understanding by presenting a more comprehensive view of several interconnected molecular processes in the overall functioning of an…

Planetary Quarantine Activities

NASA Technical Reports Server (NTRS)

1972-01-01

The activities of the Planetary Quarantine Department at Sandia Laboratories during the period April 1965 through June 1972 are summarized. Included are the rationale, the methods, and the results of modeling and experimentation used in dry heat, radiation, thermoradiation, and chemical sterilization studies. Publications describing these activities and accounts of closely related research are also furnished.

NBS: Materials measurements

NASA Technical Reports Server (NTRS)

Manning, J. R.

1981-01-01

Measurement of materials properties and thermophysical properties is described. The topics discussed are: surface tensions and their variations with temperature and impurities; convection during unidirectional solidification: measurement of high temperature thermophysical properties of tungsten liquid and solid; thermodynamic properties of refractory materials at high temperatures; and experimental and theoretical studies in wetting and multilayer adsorption.

An Introduction to Fast Fourier Transforms through the Study of Oscillating Reactions.

ERIC Educational Resources Information Center

Eastman, M. P.; And Others

1986-01-01

Discusses an experiment designed to introduce students to the basic principles of the fast Fourier transform and Fourier smoothing through transformation of time-dependent optical absorption data from an oscillating reaction. Uses the Belousov-Zhabotinskii reaction. Describes the experimental setup and data analysis techniques.

Virtual Foreign Correspondence: Experimental Instructions in Digital Foreign News Reporting

ERIC Educational Resources Information Center

Hahn, Oliver; Stalph, Florian; Steller, Tom

2018-01-01

Within a series of six qualitative studies over seven years, this research in instructing journalism students investigates whether or not covering foreign news from home via Internet technology can substitute foreign correspondents on-site to reduce costs. Co-orientation and decontextualization can be described as characteristic for virtual…

Similarity and Enhancement: Nasality from Moroccan Arabic Pharyngeals and Nasals

ERIC Educational Resources Information Center

Zellou, Georgia Eve

2012-01-01

Experimental studies of the articulation, acoustics, and perception of nasal and pharyngeal consonants and adjacent vowels were conducted to investigate nasality in Moroccan Arabic (MA). The status of nasality in MA is described as coarticulatorily complex, where two phoneme types (pharyngeal segments and nasal segments) yield similar…

A Hybrid Computer Simulation to Generate the DNA Distribution of a Cell Population.

ERIC Educational Resources Information Center

Griebling, John L.; Adams, William S.

1981-01-01

Described is a method of simulating the formation of a DNA distribution, on which statistical results and experimentally measured parameters from DNA distribution and percent-labeled mitosis studies are combined. An EAI-680 and DECSystem-10 Hybrid Computer configuration are used. (Author/CS)

Harvey Mudd College: Technology Integration Offers Unique Opportunities for Undergraduates.

ERIC Educational Resources Information Center

Barna, John; Winstead, Jim

1993-01-01

Describes undergraduate projects at Harvey Mudd College (California) that use advanced laboratory equipment and procedures normally reserved for graduate students. Examples are given in experimental biology (e.g., digital imaging and DNA analysis), in physics (e.g., using satellites to study earthquake faults), and in mathematics (e.g., teaching…

High School Biology: A Group Approach to Concept Mapping.

ERIC Educational Resources Information Center

Brown, David S.

2003-01-01

Explains concept mapping as an instructional method in cooperative learning environments, and describes a study investigating the effectiveness of concept mapping on student learning during a photosynthesis and cellular respiration unit. Reports on the positive effects of concept mapping in the experimental group. (Contains 16 references.) (YDS)

Anthropomorphizing Science: How Does It Affect the Development of Evolutionary Concepts?

ERIC Educational Resources Information Center

Legare, Cristine H.; Lane, Jonathan D.; Evans, E. Margaret

2013-01-01

Despite the ubiquitous use of anthropomorphic language to describe biological change in both educational settings and popular science, little is known about how anthropomorphic language influences children's understanding of evolutionary concepts. In an experimental study, we assessed whether the language used to convey evolutionary concepts…

How-to-Do-It: Apparatus & Experimental Design for Measuring Fermentation Rates in Yeast.

ERIC Educational Resources Information Center

Tatina, Robert

1989-01-01

Describes an apparatus that facilitates the quantitative study of fermentation in yeast by allowing simultaneous measurements of fermentation rates in several treatments and a control. Explains a laboratory procedure in which the apparatus is used. Several suggestions for further investigations are included. (Author/RT)

Paraboloids and Vortices in Hydrodynamics

ERIC Educational Resources Information Center

Goodman, John M.

1969-01-01

Describes an apparatus designed to demonstrate vortical flow of a fluid. The apparatus consists of a transparent acrylic cylinder, with a drain hole, and mounted so that it can be rotated about its axis at speeds up to 1000 rpm. Experimental observations with water as the fluid under study are reported. (LC)

Reports of the National Juvenile Justice Assessment Centers. Juvenile Delinquency Prevention Experiments: A Review and Analysis.

ERIC Educational Resources Information Center

Berleman, William C.

Ten delinquency prevention studies are reviewed that incorporated rigorous evaluative procedures (specifically the classic experimental design) for assessing programmatic outcomes. Following an introduction, the evaluation mechanisms built into each project are described, since they were used for determination of the effectiveness of the…

Novel into Film: An Experimental Course.

ERIC Educational Resources Information Center

Admussen, Richard L.; And Others

1978-01-01

A course studying narrative works from eight major French novelists, and the film adaptions of these works are described. Course discussions are directed toward a deeper understanding of the novel and a comparison of the structures, techniques, and limits of the two genres. Journal availability: Literature/Film Quarterly, Salisbury State College,…

Immersion freezing of supermicron mineral dust particles: freezing results, testing different schemes for describing ice nucleation, and ice nucleation active site densities.

PubMed

Wheeler, M J; Mason, R H; Steunenberg, K; Wagstaff, M; Chou, C; Bertram, A K

2015-05-14

Ice nucleation on mineral dust particles is known to be an important process in the atmosphere. To accurately implement ice nucleation on mineral dust particles in atmospheric simulations, a suitable theory or scheme is desirable to describe laboratory freezing data in atmospheric models. In the following, we investigated ice nucleation by supermicron mineral dust particles [kaolinite and Arizona Test Dust (ATD)] in the immersion mode. The median freezing temperature for ATD was measured to be approximately -30 °C compared with approximately -36 °C for kaolinite. The freezing results were then used to test four different schemes previously used to describe ice nucleation in atmospheric models. In terms of ability to fit the data (quantified by calculating the reduced chi-squared values), the following order was found for ATD (from best to worst): active site, pdf-α, deterministic, single-α. For kaolinite, the following order was found (from best to worst): active site, deterministic, pdf-α, single-α. The variation in the predicted median freezing temperature per decade change in the cooling rate for each of the schemes was also compared with experimental results from other studies. The deterministic model predicts the median freezing temperature to be independent of cooling rate, while experimental results show a weak dependence on cooling rate. The single-α, pdf-α, and active site schemes all agree with the experimental results within roughly a factor of 2. On the basis of our results and previous results where different schemes were tested, the active site scheme is recommended for describing the freezing of ATD and kaolinite particles. We also used our ice nucleation results to determine the ice nucleation active site (INAS) density for the supermicron dust particles tested. Using the data, we show that the INAS densities of supermicron kaolinite and ATD particles studied here are smaller than the INAS densities of submicron kaolinite and ATD particles previously reported in the literature.

Clinical Application of an Original Vascular Anastomosis: A Clinical Multicenter Study.

PubMed

Ren, Zhen-Hu; Wu, Han-Jiang; Ji, Tong; Wang, Kai; Gokavarapu, Sandhya; Zhang, Chen-Ping

2016-11-01

Vascular anastomosis is the most important technical step required for the possibility of free tissue transfer, and mismatch of the donor and recipient vessel size is the most common surgical challenge. As recent reports have described a new method (Ren anastomosis) to resolve this challenge, the goal of this study was to assess these newly described microvascular anastomosis methods. The study was conducted at 2 institutes in China in different periods. Patients were recruited from the Second Xiangya Hospital between February and May 2013 and from the Shanghai Ninth People's Hospital between March and May 2015. All patients who participated in this study needed free flaps for oral and maxillofacial defects. Patients were divided into the experimental group and the control group. In the experimental group, isometric double-notch end-in-end microvascular anastomosis (Ren anastomosis) was performed, whereas end-to-end anastomosis was performed in the control group. Statistical differences were assessed by use of χ 2 and t tests. A total of 148 patients (108 men and 40 women) were treated over the course of this study. There was a statistically significant difference (P < .001) in the operation time for the microscopic artery anastomosis between the experimental group (70 cases; 5.6 ± 1.8 minutes) and the control group (78 cases; 14.6 ± 3.7 minutes). In each group, 1 case of artery compromise was observed. The Ren anastomosis was time-saving, straightforward, efficient, and easy to learn, with a high patency rate. Copyright © 2016. Published by Elsevier Inc.

On Flowfield Periodicity in the NASA Transonic Flutter Cascade. Part 2; Numerical Study

NASA Technical Reports Server (NTRS)

Chima, Rodrick V.; McFarland, Eric R.; Wood, Jerry R.; Lepicovsky, Jan

2000-01-01

The transonic flutter cascade facility at NASA Glenn Research Center was redesigned based on a combined program of experimental measurements and numerical analyses. The objectives of the redesign were to improve the periodicity of the cascade in steady operation, and to better quantify the inlet and exit flow conditions needed for CFD predictions. Part I of this paper describes the experimental measurements, which included static pressure measurements on the blade and endwalls made using both static taps and pressure sensitive paints, cobra probe measurements of the endwall boundary layers and blade wakes, and shadowgraphs of the wave structure. Part II of this paper describes three CFD codes used to analyze the facility, including a multibody panel code, a quasi-three-dimensional viscous code, and a fully three-dimensional viscous code. The measurements and analyses both showed that the operation of the cascade was heavily dependent on the configuration of the sidewalls. Four configurations of the sidewalls were studied and the results are described. For the final configuration, the quasi-three-dimensional viscous code was used to predict the location of mid-passage streamlines for a perfectly periodic cascade. By arranging the tunnel sidewalls to approximate these streamlines, sidewall interference was minimized and excellent periodicity was obtained.

Discussion about the use of the volume specific surface area (VSSA) as a criterion to identify nanomaterials according to the EU definition. Part two: experimental approach.

PubMed

Lecloux, André J; Atluri, Rambabu; Kolen'ko, Yury V; Deepak, Francis Leonard

2017-10-12

The first part of this study was dedicated to the modelling of the influence of particle shape, porosity and particle size distribution on the volume specific surface area (VSSA) values in order to check the applicability of this concept to the identification of nanomaterials according to the European Commission Recommendation. In this second part, experimental VSSA values are obtained for various samples from nitrogen adsorption isotherms and these values were used as a screening tool to identify and classify nanomaterials. These identification results are compared to the identification based on the 50% of particles with a size below 100 nm criterion applied to the experimental particle size distributions obtained by analysis of electron microscopy images on the same materials. It is concluded that the experimental VSSA values are able to identify nanomaterials, without false negative identification, if they have a mono-modal particle size, if the adsorption data cover the relative pressure range from 0.001 to 0.65 and if a simple, qualitative image of the particles by transmission or scanning electron microscopy is available to define their shape. The experimental conditions to obtain reliable adsorption data as well as the way to analyze the adsorption isotherms are described and discussed in some detail in order to help the reader in using the experimental VSSA criterion. To obtain the experimental VSSA values, the BET surface area can be used for non-porous particles, but for porous, nanostructured or coated nanoparticles, only the external surface of the particles, obtained by a modified t-plot approach, should be considered to determine the experimental VSSA and to avoid false positive identification of nanomaterials, only the external surface area being related to the particle size. Finally, the availability of experimental VSSA values together with particle size distributions obtained by electron microscopy gave the opportunity to check the representativeness of the two models described in the first part of this study. They were also used to calculate the VSSA values and these calculated values were compared to the experimental results. For narrow particle size distributions, both models give similar VSSA values quite comparable to the experimental ones. But when the particle size distribution broadens or is of multi-bimodal shape, as theoretically predicted, one model leads to VSSA values higher than the experimental ones while the other most often leads to VSSA values lower than the experimental ones. The experimental VSSA approach then appears as a reliable, simple screening tool to identify nano and non-nano-materials. The modelling approach cannot be used as a formal identification tool but could be useful to screen for potential effects of shape, polydispersity and size, for example to compare various possible nanoforms.