Science.gov

Sample records for desenvolvimento dos meios

  1. Análise dos Conceitos Astronômicos Apresentados por Professores de Algumas Escolas Estaduais Brasileiras

    NASA Astrophysics Data System (ADS)

    Voelzke, Marcos Rincon; Gonzaga, Edson Pereira

    2011-12-01

    A razão para o desenvolvimento deste trabalho baseia-se no fato de que muitos professores da Educação Básica (EB) não lidam com conceitos relacionados à astronomia, e quando o fazem eles simplesmente seguem livros didáticos que podem conter erros conceituais. Como é de conhecimento geral a astronomia é um dos conteúdos a serem ensinados na EB fazendo parte dos Parâmetros Curriculares Nacionais e das Propostas Curriculares do Estado de São Paulo, mas é um fato, que vários pesquisadores apontam, a existência de muitos problemas no ensino da astronomia. Com o propósito de minimizar algumas dessas deficiências foi realizado um trabalho de pesquisa com a utilização de questionários pré e pós pesquisa, para tanto foi desenvolvido um Curso de Extensão Universitária para professores da Diretoria de Ensino Regional (DE) que abrange Mauá, Ribeirão Pires e Rio Grande da Serra (no Estado de São Paulo) com os seguintes objetivos: levantar concepções alternativas; subsidiar os professores por meio de palestras, debates e workshops, e verificar o sucesso da aprendizagem após o curso, adotando-se como referência, para a análise dos resultados, os dicionários de Língua Portuguesa (FERREIRA, 2004) e Enciclopédico de Astronomia e Astronáutica (MOURĀO, 1995). Portanto, dezesseis questões foram aplicadas antes e após o curso, assim pode-se verificar após a pesquisa que 100,0% dos professores sabiam os nomes das fases da Lua, 97,0% entenderam que o Sistema Solar é composto por oito planetas, 78,1% foram capazes de explicar como ocorre um eclipse lunar, um eclipse solar e um solstício, 72,7% sabiam como explicar a ocorrência das estações do ano; 64,5% explicaram corretamente a ocorrência do equinócio, 89,7% foram capazes de definir adequadamente o termo cometa; 63,6% definiram asteróide, 54,5% meteoro, 58,1% galáxia, e 42,4% planeta. Os resultados obtidos indicam uma aprendizagem significativa por parte dos participantes.

  2. Astronomia cultural e meio ambiente segundo uma abordagem holística

    NASA Astrophysics Data System (ADS)

    Jafelice, L. C.

    2003-08-01

    Neste trabalho ampliamos a discussão da abordagem holística para o ensino de astronomia que temos desenvolvido nos últimos anos, analisamos novos resultados e apresentamos exemplos práticos para interessados em experimentá-la. A constatação básica a orientar este enfoque é que cursos introdutórios em astronomia costumam ser excessiva e prematuramente técnicos, além de assumirem uma visão tradicional, muito estreita, do que seja educação científica, herdada da era cartesiana e positivista da ciência. Fundamentamos porque é importante que elementos de astronomia cultural ofereçam o mote e constituam o eixo norteador daqueles cursos e porque é urgente revermos a visão que temos da relação entre astronomia e meio ambiente. Um ponto central nesta abordagem é explorar formas de reativar e atualizar uma relação orgânica com o meio e excitar a consciência de nossa inevitável e profunda interdependência com ele em nível cósmico. Neste trabalho exemplificamos a possibilidade de concretização desta proposta em três diferentes situações: disciplinas de cursos de licenciatura em geografia e em física; escolas de nível fundamental; e, neste caso ainda a ser implementada, comunidades carentes. Estes casos envolvem públicos e espaços diferenciados para educação formal e não-formal. Dos casos já implementados, destacamos os resultados alcançados pelos alunos: enriquecimento cultural, aprendizagem significativa de conteúdos astronômicos tradicionais; mudanças de comportamento, incorporando contato diário com o céu; e freqüentes vivências de sentimentos empáticos que redirecionam a relação com a natureza e a consciência ecológica global. Além disto, para interessados em aplicar esta proposta, também socializamos procedimentos e cuidados para a implementação de ações alternativas consonantes com a mesma. (PPGECNM/UFRN; PRONEX/FINEP; NUPA/USP; Temáticos/FAPESP)

  3. Dual functional AuNRs@MnMEIOs nanoclusters for magnetic resonance imaging and photothermal therapy.

    PubMed

    Chuang, Yao-Chen; Lin, Chia-Jung; Lo, Shih-Feng; Wang, Jei-Lin; Tzou, Shey-Cherng; Yuan, Shyng-Shiou; Wang, Yun-Ming

    2014-05-01

    A novel dual functional theranosis platform is developed based on manganese magnetism-engineered iron oxide (MnMEIO) and gold nanorods (AuNRs) to combine magnetic resonance (MR) imaging and photothermal therapy in one nanocluster. The platform showed improved T2-weighted MR imaging and exhibited a near-infrared (NIR) induced temperature elevation due to the unique characteristics of AuNRs@MnMEIOs nanoclusters. The obtained dual functional spherical-shaped nanoclusters showed low cytotoxicity, and high cellular uptake efficiency. The AuNRs@MnMEIOs nanoclusters also demonstrated a 1.9 and 2.2 folds r2 relaxivity value higher than those of monodispersed MnMEIO and Resovist. In addition, in vivo MR imaging study found that the contrast enhancements were - 70.4 ± 4.3% versus - 7.5 ± 3.0% in Her-2/neu overexpression tumors as compared to the control tumors. More importantly, NIR laser irradiation to the tumor site resulted in outstanding photothermal therapeutic efficacy and without damage to the surrounding tissue. In additional, the prepared dual functional AuNRs@MnMEIOs display high stability and furthermore disperse even in the presence of external magnet, showing that AuNRs@MnMEIOs nanoclusters can be manipulated by an external magnetic field. Therefore, such nanoclusters combined MR imaging and photothermal therapeutic functionality can be developed as a promising nanosystem for effective cancer diagnosis and therapy.

  4. DOS cones along atomic chains

    NASA Astrophysics Data System (ADS)

    Kwapiński, Tomasz

    2017-03-01

    The electron transport properties of a linear atomic chain are studied theoretically within the tight-binding Hamiltonian and the Green’s function method. Variations of the local density of states (DOS) along the chain are investigated. They are crucial in scanning tunnelling experiments and give important insight into the electron transport mechanism and charge distribution inside chains. It is found that depending on the chain parity the local DOS at the Fermi level can form cone-like structures (DOS cones) along the chain. The general condition for the local DOS oscillations is obtained and the linear behaviour of the local density function is confirmed analytically. DOS cones are characterized by a linear decay towards the chain which is in contrast to the propagation properties of charge density waves, end states and Friedel oscillations in one-dimensional systems. We find that DOS cones can appear due to non-resonant electron transport, the spin–orbit scattering or for chains fabricated on a substrate with localized electrons. It is also shown that for imperfect chains (e.g. with a reduced coupling strength between two neighboring sites) a diamond-like structure of the local DOS along the chain appears.

  5. Body Size Versus Depth: Regional and Taxonomical Variation in Deep-Sea Meio- and Macrofaunal Organisms.

    PubMed

    van der Grient, Jesse M A; Rogers, Alex D

    2015-01-01

    Body size (weight per individual) is an important concept in ecology. It has been studied in the deep sea where a decrease in size with increasing depth has often been found. This has been explained as an adaptation to food limitation where size reduction results in a lowered metabolic rate and a decreased energetic requirement. However, observations vary, with some studies showing an increase in size with depth, and some finding no depth correlation at all. Here, we collected data from peer-reviewed studies on macro- and meiofaunal abundance and biomass, creating two datasets allowing statistical comparison of factors expected to influence body size in meio- and macrofaunal organisms. Our analyses examined the influence of region, taxonomic group and sampling method on the body size of meiofauna and macrofauna in the deep sea with increasing depth, and the resulting models are presented. At the global scale, meio- and macrofaunal communities show a decrease in body size with increasing depth as expected with the food limitation hypothesis. However, at the regional scale there were differences in trends of body size with depth, either showing a decrease (e.g. southwest Pacific Ocean; meio- and macrofauna) or increase (e.g. Gulf of Mexico; meiofauna only) compared to a global mean. Taxonomic groups also showed differences in body size trends compared to total community average (e.g. Crustacea and Bivalvia). Care must be taken when conducting these studies, as our analyses indicated that sampling method exerts a significant influence on research results. It is possible that differences in physiology, lifestyle and life history characteristics result in different responses to an increase in depth and/or decrease in food availability. This will have implications in the future as food supply to the deep sea changes as a result of climate change (e.g. increased ocean stratification at low to mid latitudes and reduced sea ice duration at high latitudes).

  6. Aquisição de Estreptococos Mutans e Desenvolvimento de Cárie Dental em Primogênitos

    PubMed Central

    NOCE, Erica; RUBIRA, Cassia Maria Fischer; da Silva ROSA, Odila Pereira; da SILVA, Salete Moura Bonifácio; BRETZ, Walter Antonio

    2011-01-01

    Objetivo Avaliar o momento de aquisição de estreptococos mutans (EM), desenvolvimento de cárie dental e as variáveis a eles associadas no decorrer de 23 meses, em primogênitos de famílias de baixo nível socioeconômico, desde os sete meses de idade. Método A amostra foi selecionada com base em mães densamente colonizadas por EM, incluindo todos os membros de 14 famílias que conviviam na mesma casa. Foram envolvidos no estudo 14 mães, pais e primogênitos e 8 parentes, na maioria avós. Exames clínicos e radiográficos iniciais determinaram os índices de cárie e condição periodontal dos adultos. Contagens de EM foram feitas em todos os adultos nas duas primeiras visitas. Nas crianças foram avaliados os níveis de EM, o número de dentes e de cáries, em quatro visitas. Resultados A prevalência de EM nos adultos foi alta, estando ausente em apenas um dos pais. EM foram detectados em 1, 2, 3 e 10 crianças, respectivamente nas visitas #1, 2, 3 e 4. A cárie dental foi detectada em apenas três crianças na última visita (aos 30 meses de idade), as quais apresentaram escores de EM significantemente maiores que as crianças sem cárie, na mesma visita. Conclusão Exclusivamente a condição social de baixa renda e mães densamente colonizadas por EM não são sinônimo de colonização precoce e alta atividade de cárie em crianças cuidadas em casa. O desenvolvimento de cárie está significantemente associado a escores elevados de EM nas crianças. PMID:22022218

  7. A DOS Primer for Librarians.

    ERIC Educational Resources Information Center

    Beecher, Henry

    1989-01-01

    Presents a basic orientation to the functions and capabilities of disk operating systems (DOS), aimed at the nontechnically oriented user of IBM personal computers and compatible microcomputers. Areas discussed include booting up, the use of floppy and hard disks, file storage and manipulation, and directories. Further readings are provided. (CLB)

  8. A DOS Primer for Librarians.

    ERIC Educational Resources Information Center

    Beecher, Henry

    1989-01-01

    Presents a basic orientation to the functions and capabilities of disk operating systems (DOS), aimed at the nontechnically oriented user of IBM personal computers and compatible microcomputers. Areas discussed include booting up, the use of floppy and hard disks, file storage and manipulation, and directories. Further readings are provided. (CLB)

  9. Different Roles of DosS and DosT in the Hypoxic Adaptation of Mycobacteria▿

    PubMed Central

    Kim, Min-Ju; Park, Kwang-Jin; Ko, In-Jeong; Kim, Young Min; Oh, Jeong-Il

    2010-01-01

    The DosS (DevS) and DosT histidine kinases form a two-component system together with the DosR (DevR) response regulator in Mycobacterium tuberculosis. DosS and DosT, which have high sequence similarity to each other over the length of their amino acid sequences, contain two GAF domains (GAF-A and GAF-B) in their N-terminal sensory domains. Complementation tests in conjunction with phylogenetic analysis showed that DevS of Mycobacterium smegmatis is more closely related to DosT than DosS. We also demonstrated in vivo that DosS and DosT of M. tuberculosis play a differential role in hypoxic adaptation. DosT responds to a decrease in oxygen tension more sensitively and strongly than DosS, which might be attributable to their different autooxidation rates. The different responsiveness of DosS and DosT to hypoxia is due to the difference in their GAF-A domains accommodating the hemes. Multiple alignment analysis of the GAF-A domains of mycobacterial DosS (DosT) homologs and subsequent site-directed mutagenesis revealed that just one substitution of E87, D90, H97, L118, or T169 of DosS with the corresponding residue of DosT is sufficient to convert DosS to DosT with regard to the responsiveness to changes in oxygen tension. PMID:20675480

  10. O que bilíngues bimodais têm a nos dizer sobre desenvolvimento bilíngue?

    PubMed Central

    de Quadros, Ronice Müller; Lillo-Martin, Diane; Pichler, Deborah Chen

    2013-01-01

    O objetivo deste trabalho é apresentar o que as pesquisas que estamos desenvolvendo com crianças ouvintes, filhas de pais surdos, adquirindo Língua Brasileira de Sinais (Libras) e Português e Língua de Sinais Americana (ASL) e Inglês (Lillo-Martin et al. 2010) têm a nos dizer sobre desenvolvimento bilíngue. Os dados deste estudo fazem parte de um banco de dados de interações espontâneas coletadas longitudinalmente, alternando contextos de aquisição da Libras e do português como língua alvo, no Brasil e dados coletados longitudinalmente. nos mesmos contextos, de crianças adquirindo ASL e inglês1. Além disso, há também dados do estudo experimental com testes aplicados nos dois pares de línguas que se agregam ao presente estudo. Uma visão geral dos estudos desenvolvidos sobre a aquisição bilíngue bimodal por crianças ouvintes, filhas de pais surdos, será apresentada e, então, serão expostos alguns aspectos linguísticos deste tipo de aquisição, considerando as discussões sobre aquisição bilíngue a partir da pesquisa realizada. PMID:24431480

  11. DIGLIB. PC-DOS Graphics Subroutine Library

    SciTech Connect

    Burleson, R.R.

    1989-02-01

    DIGLIB is a collection of general graphics subroutines. It was designed to be small, reasonably fast, device-independent, and compatible with DEC-supplied operating systems for VAXes, PDP-11s, and LSI-11s, and the DOS operating system for IBM PCs and IBM-compatible machines. DIGLIB/PC runs on IBM PCs under PC-DOS or MS-DOS. The software is readily usable by casual programmers for two-dimensional plotting.

  12. Self-regulating the effortful "social dos".

    PubMed

    Cortes, Kassandra; Kammrath, Lara K; Scholer, Abigail A; Peetz, Johanna

    2014-03-01

    In the current research, we explored differences in the self-regulation of the personal dos (i.e., engaging in active and effortful behaviors that benefit the self) and in the self-regulation of the social dos (engaging in those same effortful behaviors to benefit someone else). In 6 studies, we examined whether the same trait self-control abilities that predict task persistence on personal dos would also predict task persistence on social dos. That is, would the same behavior, such as persisting through a tedious and attentionally demanding task, show different associations with trait self-control when it is framed as benefitting the self versus someone else? In Studies 1-3, we directly compared the personal and social dos and found that trait self-control predicted self-reported and behavioral personal dos but not social dos, even when the behaviors were identical and when the incentives were matched. Instead, trait agreeableness--a trait linked to successful self-regulation within the social domain--predicted the social dos. Trait self-control did not predict the social dos even when task difficulty increased (Study 4), but it did predict the social don'ts, consistent with past research (Studies 5-6). The current studies provide support for the importance of distinguishing different domains of self-regulated behaviors and suggest that social dos can be successfully performed through routes other than traditional self-control abilities. (PsycINFO Database Record (c) 2014 APA, all rights reserved).

  13. Combined use of meio- and macrobenthic indices to assess complex chemical impacts on a stream ecosystem

    NASA Astrophysics Data System (ADS)

    McKnight, Ursula S.; Sonne, Anne T.; Rasmussen, Jes J.; Traunspurger, Walter; Höss, Sebastian; Bjerg, Poul L.

    2016-04-01

    habitats for overall ecosystem health, many biological indices tend only to reflect the ecological quality of surface water, rather than of the sedimentary zones where the accumulation of pollutants is often highest. To address this issue, we monitored meiobenthic (i.e. nematodes) and macrobenthic invertebrate communities along a pollution gradient in order to assess the impact of multiple stressors on a groundwater-fed stream, and thus quantify the link between chemical and ecological status. The studied stressors included point source pollutants originating from contaminated groundwater and aquaculture, and diffuse source pollutants originating from conventional agriculture and urban areas. The use of macrofauna is now well-accepted for assessing ecological integrity in aquatic ecosystems, but less is known about the application of meiofaunal community indicators. High abundance and ubiquitous distribution are two potential advantages for including meiofaunal indicators, and notably - for the case of groundwater-surface water interactions - they are particularly suitable for identifying changes in environmental conditions over smaller spatial scales. The results indicate a change in community composition for both meio- and macrobenthic fauna, pointing towards the presence of a local impact resulting from the discharging contaminated groundwater, which extends downstream along a dilution gradient of the groundwater contaminants. Ecological impacts could be linked to xenobiotic compounds coming from groundwater (both chlorinated solvents and pharmaceuticals), as well as the presence of trace metals of diffuse and/or biogenic origin.

  14. A DOS Primer for Librarians: Part II.

    ERIC Educational Resources Information Center

    Beecher, Henry

    1990-01-01

    Provides an introduction to DOS commands and strategies for the effective organization and use of hard disks. Functions discussed include the creation of directories and subdirectories, enhanced copying, the assignment of disk drives, and backing up the hard disk. (CLB)

  15. A DOS Primer for Librarians: Part II.

    ERIC Educational Resources Information Center

    Beecher, Henry

    1990-01-01

    Provides an introduction to DOS commands and strategies for the effective organization and use of hard disks. Functions discussed include the creation of directories and subdirectories, enhanced copying, the assignment of disk drives, and backing up the hard disk. (CLB)

  16. Dynamic sedimentary environments of an Arctic glacier-fed river estuary (Adventfjorden, Svalbard). II: Meio- and macrobenthic fauna

    NASA Astrophysics Data System (ADS)

    Włodarska-Kowalczuk, Maria; Szymelfenig, Maria; Zajiczkowski, Marek

    2007-08-01

    The paper examines the meio- and macrobenthic responses to physical disturbance and sediment instabilities in a small Arctic glacier-fed river estuary. Zajiczkowski and Włodarska-Kowalczuk [Zajiczkowski, M., Włodarska-Kowalczuk, M., 2007. Dynamic sedimentary environments of Arctic glacier-fed river estuary (Adventfjorden, Svalbard). I. Flux, deposition, and sediment dynamics. Estuarine, Coastal and Shelf Science 74(1-2), 285-296] distinguished three zones in Adventfjorden (west Spitsbergen) estuary: the tidal flat, the slope (high sedimentation, frequent sediment slides), the central basin (low sedimentation, stable sediments). The numbers of individuals and species of meio- and macrofauna were very low on the tidal flat. The total densities of meio- and macrofauna were significantly lower on the slope of the glacio-fluvial delta than in the central basin. Only the macrofauna responded to sediment instabilities on the slope by a significant decrease in total biomass. Nematodes inhabiting the slope sediments were larger than those in the central basin, although there was no significant difference in the size of harpacticoids in the two zones. The frequently disturbed, resuspended, and redeposited slope sediments were colonized by the opportunistic polychaete Capitella capitata agg. and by the high sedimentation resistant polychaetes Chaetozone setosa agg. and Cossura longocirrata. Tube-dwelling, sedentary, or suspension-feeding fauna only occurred at the central basin stations. The species richness and ratio of surface-dwelling to burrowing deposit-feeders in the macrobenthic communities decreased towards the river mouths. The differences in the taxonomic composition of communities inhabiting the sediments of the slope and the central basin were less pronounced in meiofauna (studied at a higher taxonomic level) than in the macrofauna (identified to the species level). Nevertheless, the differences were significant for both benthic compartments (ANOSIM test, P < 0

  17. Development of Bifunctional Gadolinium-Labeled Superparamagnetic Nanoparticles (Gd-MnMEIO) for In Vivo MR Imaging of the Liver in an Animal Model

    PubMed Central

    Liu, Gin-Chung; Wang, Yun-Ming

    2016-01-01

    Liver tumors are common and imaging methods, particularly magnetic resonance imaging (MRI), play an important role in their non-invasive diagnosis. Previous studies have shown that detection of liver tumors can be improved by injection of two different MR contrast agents. Here, we developed a new contrast agent, Gd-manganese-doped magnetism-engineered iron oxide (Gd-MnMEIO), with enhancement effects on both T1- and T2-weighted MR images of the liver. A 3.0T clinical MR scanner equipped with transmit/receiver coil for mouse was used to obtain both T1-weighted spoiled gradient-echo and T2-weighted fast spin-echo axial images of the liver before and after intravenous contrast agent injection into Balb/c mice with and without tumors. After pre-contrast scanning, six mice per group were intravenously injected with 0.1 mmol/kg Gd-MnMEIO, or the control agents, i.e., Gd-DTPA or SPIO. The scanning time points for T1-weighted images were 0.5, 5, 10, 15, 20, 25, and 30 min after contrast administration. The post-enhanced T2-weighted images were then acquired immediately after T1-weighted acquisition. We found that T1-weighted images were positively enhanced by both Gd-DTPA and Gd-MnMEIO and negatively enhanced by SPIO. The enhancement by both Gd-DTPA and Gd-MnMEIO peaked at 0.5 min and gradually declined thereafter. Gd-MnMEIO (like Gd-DTPA) enhanced T1-weighted images and (like SPIO) T2-weighted images. Marked vascular enhancement was clearly visible on dynamic T1-weighted images with Gd-MnMEIO. In addition, the T2 signal was significantly decreased at 30 min after administration of Gd-MnMEIO. Whereas the effects of Gd-MnMEIO and SPIO on T2-weighted images were similar (p = 0.5824), those of Gd-MnMEIO and Gd-DTPA differed, with Gd-MnMEIO having a significant T2 contrast effect (p = 0.0086). Our study confirms the feasibility of synthesizing an MR contrast agent with both T1 and T2 shortening effects and using such an agent in vivo. This agent enables tumor detection and

  18. Desenvolvimento das câmeras de raios-X duros do satélite MIRAX

    NASA Astrophysics Data System (ADS)

    Braga, J.; Rothschild, R.; Staubert, R.; Heise, J.; Remillard, R.; D'Amico, F.; Jablonski, F.; Mejía, J.; Carvalho, H.; Heindl, B.; Matteson, J.; Kendziorra, E.; Wilms, J.; in't Zand, J.; Kuulkers, E.

    2003-08-01

    O MIRAX (Monitor e Imageador de RAios-X) é um projeto de desenvolvimento de um pequeno satélite astronômico de raios-X (~200 kg, ~240 W). A estratégia básica da missão será observar continuamente (~9 meses por ano) a região central (~1000 graus2) do plano Galáctico e realizar estudos espectroscópicos de banda larga (2-200 keV) e alta sensibilidade de um grande conjunto de fontes através de imagens com resolução de ~6'. Isso proporcionará uma cobertura inédita do "espaço de descobertas" através da detecção, localização, identificação e estudo detalhado de fenômenos imprevisíveis, tais como transientes fracos de raios-X, novas rápidas de raios-X e bursts de raios gama, assim como o estudo de fontes com emissão persistente. Neste trabalho apresentamos o projeto das duas câmeras de raios-X duros (CXDs) do MIRAX, que irão operar na faixa de 10 a 200 keV. Cada CXD consistirá de um plano de detectores CZT (Cd0,9Zn0,1Te) de 0,5 mm de resolução espacial e 370 cm2 de área total, e de uma máscara codificada com elementos quadrados de 1,3 mm de lado e 0,5 cm de espessura. A máscara terá dimensões de 315 cm ´ 275 cm e será montada a 700 cm de distância dos detectores. Com essa configuração as CXDs terão 6' de resolução angular e, quando colocadas a um ângulo de 29° entre si, as duas câmeras propiciam um campo totalmente codificado de 39° ´ 6°12' e um campo total de 76° ´ 44°. Serão apresentadas simulações de observações da região do plano Galáctico com o conjunto formado pelas duas CXDs.

  19. The Meio 1498 earthquake and tsunami : driving force of abrupt environmental change in the Hamana floodplain, Shizuoka prefecture, Japan.

    NASA Astrophysics Data System (ADS)

    Heyvaert, Vanessa M. A.; Fujiwara, Osamu; Umitsu, Masatomo; Sato, Yoshiki; Ono, Einsuke; Yata, Toshifumi

    2013-04-01

    The objective of this research is to study the role of a tsunami, generated by the 1498 Meio earthquake (M8.2 - 8.4) along the eastern Nankai on the geomorphological evolution of the Hamana river floodplain, located along the Pacific coastline of Central Japan (Shizuoka prefecture). Historical sources document a sudden decline at the end of the 15th century of the harbour town Hashimoto, located along the river Hamana. Before the 15th century, this river connected the Pacific Ocean with an enclosed coastal embayment separated by a sand barrier (i.e. the present-day Hamana lake) from the Pacific. The reconstruction of the palaeocourse of the Hamana river was carried out on the basis of detailed facies and diatom analyses of undisturbed sediment cores (geoslicer and drilling). The palaeochannel was detected along the western side of the present-day coastal embayment. It seems that the river's mouth was abruptly sealed off due to the migration of huge volumes of sand that initiated the development of a marsh environment upstream along the channel. The identification and radiocarbon dating of these sandy high-energy flow deposits in several cores (thick sand bed of marine origin intercalated at the estuarine - marsh environmental change boundary) suggests that the river mouth closure was initated by mass sediment transport by a storm surge or tsunami (1498 Meio tsunami and/or 1498 and 1499 large storm surges along the Hamana coastline). The same process, of sudden river mouth sealing by tsunami-transported sediments, was recently observed in the northeast of Japan during the great 2011 Sendai tsunami (Uda, T., 2011). Historical sources document that after the 1498 Meio tsunami, the Hamana back-barrier sheltered environment was reconnected to the Pacific Ocean due to breaching of its sand barrier. Both environmental changes (river mouth closure and barrier breaching)are synchronous with the sudden decline of the harbour town Hashimoto. These data suggest that disruption

  20. Size matters at deep-sea hydrothermal vents: different diversity and habitat fidelity patterns of meio- and macrofauna

    PubMed Central

    Gollner, Sabine; Govenar, Breea; Fisher, Charles R.; Bright, Monika

    2015-01-01

    Species with markedly different sizes interact when sharing the same habitat. Unravelling mechanisms that control diversity thus requires consideration of a range of size classes. We compared patterns of diversity and community structure for meio- and macrofaunal communities sampled along a gradient of environmental stress at deep-sea hydrothermal vents on the East Pacific Rise (9° 50′ N) and neighboring basalt habitats. Both meio- and macrofaunal species richnesses were lowest in the high-stress vent habitat, but macrofaunal richness was highest among intermediate-stress vent habitats. Meiofaunal species richness was negatively correlated with stress, and highest on the basalt. In these deep-sea basalt habitats surrounding hydrothermal vents, meiofaunal species richness was consistently higher than that of macrofauna. Consideration of the physiological capabilities and life history traits of different-sized animals suggests that different patterns of diversity may be caused by different capabilities to deal with environmental stress in the 2 size classes. In contrast to meiofauna, adaptations of macrofauna may have evolved to allow them to maintain their physiological homeostasis in a variety of hydrothermal vent habitats and exploit this food-rich deep-sea environment in high abundances. The habitat fidelity patterns also differed: macrofaunal species occurred primarily at vents and were generally restricted to this habitat, but meiofaunal species were distributed more evenly across proximate and distant basalt habitats and were thus not restricted to vent habitats. Over evolutionary time scales these contrasting patterns are likely driven by distinct reproduction strategies and food demands inherent to fauna of different sizes. PMID:26166922

  1. Size matters at deep-sea hydrothermal vents: different diversity and habitat fidelity patterns of meio- and macrofauna.

    PubMed

    Gollner, Sabine; Govenar, Breea; Fisher, Charles R; Bright, Monika

    2015-02-03

    Species with markedly different sizes interact when sharing the same habitat. Unravelling mechanisms that control diversity thus requires consideration of a range of size classes. We compared patterns of diversity and community structure for meio- and macrofaunal communities sampled along a gradient of environmental stress at deep-sea hydrothermal vents on the East Pacific Rise (9° 50' N) and neighboring basalt habitats. Both meio- and macrofaunal species richnesses were lowest in the high-stress vent habitat, but macrofaunal richness was highest among intermediate-stress vent habitats. Meiofaunal species richness was negatively correlated with stress, and highest on the basalt. In these deep-sea basalt habitats surrounding hydrothermal vents, meiofaunal species richness was consistently higher than that of macrofauna. Consideration of the physiological capabilities and life history traits of different-sized animals suggests that different patterns of diversity may be caused by different capabilities to deal with environmental stress in the 2 size classes. In contrast to meiofauna, adaptations of macrofauna may have evolved to allow them to maintain their physiological homeostasis in a variety of hydrothermal vent habitats and exploit this food-rich deep-sea environment in high abundances. The habitat fidelity patterns also differed: macrofaunal species occurred primarily at vents and were generally restricted to this habitat, but meiofaunal species were distributed more evenly across proximate and distant basalt habitats and were thus not restricted to vent habitats. Over evolutionary time scales these contrasting patterns are likely driven by distinct reproduction strategies and food demands inherent to fauna of different sizes.

  2. 27 CFR 9.175 - Dos Rios.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... is located in northern Mendocino County, California, at the confluence of the Eel River and the Middle Fork of the Eel River. The area's boundaries are defined as follows— (1) Beginning in the... the Middle Fork of the Eel River, to the southeast corner of section 11, T21N, R13W (Dos...

  3. "DOS for Managers." Management Training Series.

    ERIC Educational Resources Information Center

    Marion County Schools, Fairmont, WV.

    A plan is provided for a lesson on disk operating systems (DOS) for managers. Twenty-five lesson objectives are listed, followed by suggestions for learning activities and special resources. In the presentation section, key points and content are provided for 25 instructional topics that correspond to the 25 lesson objectives. The topics are as…

  4. DOS: the discrete-ordinates system. [LMFBR

    SciTech Connect

    Rhoades, W. A.; Emmett, M. B.

    1982-09-01

    The Discrete Ordinates System determines the flux of neutrons or photons due either to fixed sources specified by the user or to sources generated by particle interaction with the problem materials. It also determines numerous secondary results which depend upon flux. Criticality searches can be performed. Numerous input, output, and file manipulation facilities are provided. The DOS driver program reads the problem specification from an input file and calls various program modules into execution as specified by the input file.

  5. DIGLIB. PC-DOS Graphics Subroutine Library

    SciTech Connect

    Brand, H.R.

    1989-02-01

    DIGLIB is a collection of general graphics subroutines. It was designed to be small, reasonably fast, device-independent, and compatible with DEC-supplied operating systems for VAXes, PDP-11s, and LSI-11s, and the DOS operating system for IBM PCs and IBM-compatible machines. DIGLIB/VMS runs on the VAX and MicroVAX series of computers under VMS. The software is readily usable by casual programmers for two-dimensional plotting.

  6. Influence of seagrass beds and oyster parks on the abundance and biomass patterns of meio- and macrobenthos in tidal flats

    NASA Astrophysics Data System (ADS)

    Castel, Jacques; Labourg, Pierre-Jean; Escaravage, Vincent; Auby, Isabelle; Garcia, Maria Elena

    1989-01-01

    In Arcachon Bay, on the south-west coast of France, the intertidal area is mainly occupied by sandbanks, oyster parks ( Crassostrea gigas) and mud flats covered with seagrass beds ( Zostera noltii). In order to estimate the relative contribution of meio- and macrofauna to the benthic ecology of these tidal flats, seven stations were studied seasonally for a year. Relationships between faunal density and biomass, and external factors such as sediment structure, benthic chlorophyll and seagrass debris were investigated. A comparison was made between bare sands, oyster beds and vegetated sediment in semi-exposed conditions and in sheltered areas. Using a stepwise method of multiple linear regression it was shown that high densities of macrobenthos are mostly explained by high quantities of plant debris. For meiofauna, together with plant debris, other effective variables are involved: silt content, organic carbon, chlorophyll pigments. On an average, a correlation between macro- and meiofaunal abundances could be found. However, this general pattern is modified by the biogenic structure created by the oysters and seagrass. When compared to the adjacent sandbanks, oysters clearly enhanced meiofaunal abundance (from 1130-4170 individuals 10 cm -2) but depressed macrofaunal densities (from 640-370 individuals 400 cm -2). The organic-rich oyster biodeposits probably favour meiofauna by an increase of the trophic resources but do not favour macroinfauna by inducing low oxygen concentrations. Moreover, it is likely that macrofauna is more sensitive to predation than meiofauna both in sandbanks and in oyster parks. For both meio- and macrofauna the highest incidences (7200 individuals 10 cm -2 and 2470 individuals 400 cm -2, respectively) are recorded in seagrass bed sediments. Zostera induces an enhancement of organic detritus and provides a refuge against predation. In terms of biomass, the macrofauna/meiofauna ratio is 25·1 in sandbanks, 1·5 in oyster parks and 4·2 in

  7. Disk Operating System--DOS. Teacher Packet. Learning Activity Packets.

    ERIC Educational Resources Information Center

    Oklahoma State Dept. of Vocational and Technical Education, Stillwater. Curriculum and Instructional Materials Center.

    The Learning Activity Packets (LAPs) contained in this manual are designed to assist the beginning user in understanding DOS (Disk Operating System). LAPs will not work with any version below DOS Version 3.0 and do not address the enhanced features of versions 4.0 or higher. These elementary activities cover only the DOS commands necessary to…

  8. [The occurrence of Biomphalaria straminea (Pulmonata: Planorbidae) on an aquaculture farm of IBAMA in Uberlândia, MG. Instituto Brasileiro do Meio Ambiente a dos Recursos Naturais Renováveis].

    PubMed

    Silveira, E de P; Marçal Júnior, O; Machado, M I

    1997-01-01

    This work evaluates the occurrence of freshwater snails in the IBAMA's fish breeding station in Uberlândia, Minas Gerais State. We verified the presence of Biomphalaria straminea in 39.5% of all breeding tanks. None of the snails were infected by Schistosoma mansoni, but further investigation should be done in the area.

  9. Strains of the East Asian (W/Beijing) Lineage of Mycobacterium tuberculosis Are DosS/DosT-DosR Two-Component Regulatory System Natural Mutants▿ †

    PubMed Central

    Fallow, Ashley; Domenech, Pilar; Reed, Michael B.

    2010-01-01

    As part of our ongoing efforts to uncover the phenotypic consequences of genetic variability among clinical Mycobacterium tuberculosis isolates, we previously reported that isolates of the “East Asian” or “W/Beijing” lineage constitutively overexpress the coordinately regulated transcriptional program known as the DosR regulon under standard in vitro conditions. This phenotype distinguishes the W/Beijing lineage from all other M. tuberculosis lineages, which normally induce expression of this regulon only once exposed to low oxygen or nitric oxide, both of which result in inhibition of bacterial respiration and replication. Transcription of the DosR regulon is controlled through a two-component regulatory system comprising the transcription factor DosR and two possible cognate histidine sensor kinases, DosS and DosT. Through sequence analysis of a carefully selected set of isolates representing each of the major M. tuberculosis lineages, we describe herein a naturally occurring frameshift mutation in the gene encoding the DosT sensor kinase for isolates of the most recently evolved W/Beijing sublineages. Intriguingly, the occurrence of the frameshift mutation correlates precisely with the appearance of the constitutive DosR regulon phenotype displayed by the same “modern” W/Beijing strains. However, complementation studies have revealed that the mutation in dosT alone is not directly responsible for the constitutive DosR regulon phenotype. Our data serve to highlight the evolutionary pressure that exists among distinct M. tuberculosis lineages to maintain tight control over DosR regulon expression. PMID:20154135

  10. Inhibitors of Mycobacterium tuberculosis DosRST signaling and persistence.

    PubMed

    Zheng, Huiqing; Colvin, Christopher J; Johnson, Benjamin K; Kirchhoff, Paul D; Wilson, Michael; Jorgensen-Muga, Katriana; Larsen, Scott D; Abramovitch, Robert B

    2017-02-01

    The Mycobacterium tuberculosis (Mtb) DosRST two-component regulatory system promotes the survival of Mtb during non-replicating persistence (NRP). NRP bacteria help drive the long course of tuberculosis therapy; therefore, chemical inhibition of DosRST may inhibit the ability of Mtb to establish persistence and thus shorten treatment. Using a DosRST-dependent fluorescent Mtb reporter strain, a whole-cell phenotypic high-throughput screen of a ∼540,000 compound small-molecule library was conducted. The screen discovered novel inhibitors of the DosRST regulon, including three compounds that were subject to follow-up studies: artemisinin, HC102A and HC103A. Under hypoxia, all three compounds inhibit Mtb-persistence-associated physiological processes, including triacylglycerol synthesis, survival and antibiotic tolerance. Artemisinin functions by disabling the heme-based DosS and DosT sensor kinases by oxidizing ferrous heme and generating heme-artemisinin adducts. In contrast, HC103A inhibits DosS and DosT autophosphorylation activity without targeting the sensor kinase heme.

  11. CRONUS, A Distributed Operating System. Volume 4. CRONUS DOS implementation

    DTIC Science & Technology

    1988-06-01

    3 VI’(of i,:oa4r) TC- ’ CRON S, A DISTRIBUTED OPERATING S YS^4T EM: CRONUS DOS Implementation .131N Laboratories Incorporated R~. Schantz, K...Classification) CRONUS , A DISTRIBUTED OPERATING SYSTEM: CRONUS DOS Implementation 1Z.P ERSONAL AUTHOR(S) R. Schantz, K. Schroder, M. Barrow, G. Bono, M. Dean, R...second contract phase for development of the Cronus Project. ’% Cronus is the name given to the distributed operating system (DOS) and system

  12. Divorce Matters: Visitation Dos and Don'ts

    MedlinePlus

    divorce matters Visitation dos and don’ts For both parents and children, visitation is critical to maintaining ... sense of connectedness both during and after a divorce. But in the early stages of family restructuring ...

  13. Izabel dos Santos and the training of the health workers.

    PubMed

    Paiva, Carlos Henrique Assunção

    2015-06-01

    This article discusses the career of Izabel dos Santos (1927-2010) as a means of examining the connections between health schools and agendas in contemporary Brazil. The article highlights dos Santos's training and her work in the Serviço Especial de Saúde Pública (SESP- Special Public Health Service), the Pan American Health Organization (PAHO) and in the formulation and implementation of national training programs for human resources within the area of health from the late 1970s onwards. The article highlights dos Santos's central role in the formulation and implementation of training policies for health workers, especially nursing technicians and assistants, and demonstrates how she occupies an important place in the history of Brazilian public health.

  14. Isotopic and chemical investigations on Angra dos Reis

    NASA Technical Reports Server (NTRS)

    Wasserburg, G. J.; Tera, F.; Papanastassiou, D. A.; Huneke, J. C.

    1977-01-01

    Isotope ratios and chemical abundance measurements for a variety of elements are reported for total meteorite and mineral separates of the Angra dos Reis achondrite. U-Pb, Th-Pb, and Pb-Pb ages are concordant at 4.54 eons for the total meteorite and for high-purity whitlockite, which indicates that Angra dos Reis is an early planetary differentiate that has not been disturbed for these systems since 4.54 eons ago. The implications of different ratios of Sr-87 and Sr-86 found in different components are discussed. Xe isotopic measurements show that Pu-244 was enriched in the whitlockite relative to the pyroxene by a factor of about 18. Chemical enrichment factors between the whitlockite and the fassaitic pyroxene in Angra dos Reis are presented

  15. When worlds collide - Mac to MS-DOS. [Data transfer to and from Apple Macintosh computers and MS-DOS based personal computers

    SciTech Connect

    Busbey, A.B.

    1989-04-01

    A number of methods and products, both hardware and software, to allow data exchange between Apple Macintosh computers and MS-DOS based systems. These included serial null modem connections, MS-DOS hardware and/or software emulation, MS-DOS disk-reading hardware and networking.

  16. 48 CFR 619.402-70 - DOS designee.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Section 619.402-70 Federal Acquisition Regulations System DEPARTMENT OF STATE SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Cooperation with the Small Business Administration 619.402-70 DOS designee. Where the FAR requires action by a Small Business Administration procurement center representative, but one has not been...

  17. Special Section--Library Workstations: Mac and DOS.

    ERIC Educational Resources Information Center

    Valauskas, Ed; Flower, Eric

    1993-01-01

    Two articles discuss the library hardware marketplace. The first examines the Apple Macintosh in libraries from 1984 to the present, including linking libraries, computers, and endusers over large geographic distances. The second article discusses upgrading components of systems in the IBM compatible, MS-DOS, and Windows environments as costs…

  18. Ultrafast ligand dynamics in the heme-based GAF sensor domains of the histidine kinases DosS and DosT from Mycobacterium tuberculosis†

    PubMed Central

    Vos, Marten H.; Bouzhir-Sima, Latifa; Lambry, Jean-Christophe; Luo, Hao; Eaton-Rye, Julian J.; Ioanoviciu, Alexandra; Ortiz de Montellano, Paul R.; Liebl, Ursula

    2011-01-01

    The transcriptional regulator DosR from M. tuberculosis plays a crucial role in the virulence to dormancy transition of the pathogen. DosR can be activated by DosT and DosS, two histidine kinases with heme-containing sensor GAF domains, capable of diatomic ligand binding, To investigate the initial processes occurring upon ligand dissociation, we performed ultrafast time-resolved absorption spectroscopy of the isolated sensor domains ligated with O2, NO and CO. The results reveal a relatively closed heme pocket for both proteins. For DosT the yield of O2 escape from the heme pocket on the picoseconds timescale upon photodissociation was found to be very low (1.5%), similar to other heme-based oxygen sensor proteins, implying that this sensor acts as an effective O2 trap. Remarkably, this yield is an order of magnitude higher in DosS (18%). For CO, by contrast, the fraction of CO rebinding within the heme pocket is higher in DosS. Experiments with mutant DosT sensor domains and molecular dynamics simulations indicate an important role in ligand discrimination of the distal tyrosine, present in both proteins, which forms a hydrogen bond with heme-bound O2. We conclude that despite their similarity, DosT and DosS display ligand-specific different primary dynamics during the initial phases of intra-protein signaling. The distal tyrosine, present in both proteins, plays an important role in these processes. PMID:22142262

  19. Deceiving entropy-based DoS detection

    NASA Astrophysics Data System (ADS)

    Özçelik, Ä.°lker; Brooks, Richard R.

    2014-06-01

    Denial of Service (DoS) attacks disable network services for legitimate users. A McAfee report shows that eight out of ten Critical Infrastructure Providers (CIPs) surveyed had a significant Distributed DoS (DDoS) attack in 2010.1 Researchers proposed many approaches for detecting these attacks in the past decade. Anomaly based DoS detection is the most common. In this approach, the detector uses statistical features; such as the entropy of incoming packet header fields like source IP addresses or protocol type. It calculates the observed statistical feature and triggers an alarm if an extreme deviation occurs. However, intrusion detection systems (IDS) using entropy based detection can be fooled by spoofing. An attacker can sniff the network to collect header field data of network packets coming from distributed nodes on the Internet and fuses them to calculate the entropy of normal background traffic. Then s/he can spoof attack packets to keep the entropy value in the expected range during the attack. In this study, we present a proof of concept entropy spoofing attack that deceives entropy based detection approaches. Our preliminary results show that spoofing attacks cause significant detection performance degradation.

  20. 33 CFR 105.245 - Declaration of Security (DoS).

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... DoS and for handling DoS requests from a vessel. (b) At MARSEC Level 1, a facility receiving a cruise ship or a manned vessel carrying Certain Dangerous Cargo, in bulk, must comply with the following:...

  1. 33 CFR 105.245 - Declaration of Security (DoS).

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... DoS and for handling DoS requests from a vessel. (b) At MARSEC Level 1, a facility receiving a cruise ship or a manned vessel carrying Certain Dangerous Cargo, in bulk, must comply with the following:...

  2. 33 CFR 105.245 - Declaration of Security (DoS).

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... DoS and for handling DoS requests from a vessel. (b) At MARSEC Level 1, a facility receiving a cruise ship or a manned vessel carrying Certain Dangerous Cargo, in bulk, must comply with the following:...

  3. Structures of Mycobacterium tuberculosis DosR and DosR-DNA Complex Involved in Gene Activation during Adaptation to Hypoxic Latency

    SciTech Connect

    Wisedchaisri, Goragot; Wu, Meiting; Rice, Adrian E; Roberts, David M; Sherman, David R; Hol, Wim G.J.

    2010-07-20

    On encountering low oxygen conditions, DosR activates the transcription of 47 genes, promoting long-term survival of Mycobacterium tuberculosis in a non-replicating state. Here, we report the crystal structures of the DosR C-terminal domain and its complex with a consensus DNA sequence of the hypoxia-induced gene promoter. The DosR C-terminal domain contains four {alpha}-helices and forms tetramers consisting of two dimers with non-intersecting dyads. In the DNA-bound structure, each DosR C-terminal domain in a dimer places its DNA-binding helix deep into the major groove, causing two bends in the DNA. DosR makes numerous protein-DNA base contacts using only three amino acid residues per subunit: Lys179, Lys182, and Asn183. The DosR tetramer is unique among response regulators with known structures.

  4. Detection of DoS attacks using intrusion detection sensors

    NASA Astrophysics Data System (ADS)

    Ramakrishna, Pathmenanthan; Maarof, Mohd A.

    2002-09-01

    Intrusion detection systems have usually been developed using large host-based components. These components impose an extra load on the system where they run (sometimes even requiring a dedicated system) and are subject to tampering or disabling by an intruder. Additionally, intrusion detection systems have usually obtained information about host behavior through indirect means, such as audit trails or network packet traces. This potentially allows intruders to modify the information before the intrusion detection system obtains it and slows down the detection and prevention of DoS attacks, making it possible for an intruder to hide his activities. In this paper we propose work that will attempt to show that it is possible to perform intrusion detection mechanism of DoS attacks using small sensors embedded in a computer system. These sensors will look for signs of specific intrusions. They will perform target monitoring by observing the behavior of the through an audit trail or other indirect means in real time while the Snort IDS running. Furthermore, by being built into the computer system it could provide a flexible alert sensor which may not impose a considerable extra load on the host they monitor.

  5. Sedimentation survey of Lago Dos Bocas, Puerto Rico, June 1985

    USGS Publications Warehouse

    Quinones, Ferdinand; Melendez, Frank; Bonnet, Carlos

    1989-01-01

    A survey of the sedimentation of Dos Bocas reservoir, in central Puerto Rico, was conducted during July 1985. The survey showed that the capacity of the reservoir has declined from 30,420 acre-ft in 1942 to about 19,620 acre-ft. Sediment is accumulating in the reservoir at an average rate of about 251 acre-ft/yr, or about 0.83%/yr of the original capacity. The expected usable life of the reservoir on the basis of the long-term sedimentation rate is about 78 years. However, the sedimentation rate appears to have increased significantly since 1979. During the last six years, the average sedimentation rate has exceeded 600 acre-ft/yr. If this rate is maintained, the expected usable life of the reservoir would be about 32 years. (Author 's abstract)

  6. Document image archive transfer from DOS to UNIX

    NASA Technical Reports Server (NTRS)

    Hauser, Susan E.; Gill, Michael J.; Thoma, George R.

    1994-01-01

    An R&D division of the National Library of Medicine has developed a prototype system for automated document image delivery as an adjunct to the labor-intensive manual interlibrary loan service of the library. The document image archive is implemented by a PC controlled bank of optical disk drives which use 12 inch WORM platters containing bitmapped images of over 200,000 pages of medical journals. Following three years of routine operation which resulted in serving patrons with articles both by mail and fax, an effort is underway to relocate the storage environment from the DOS-based system to a UNIX-based jukebox whose magneto-optical erasable 5 1/4 inch platters hold the images. This paper describes the deficiencies of the current storage system, the design issues of modifying several modules in the system, the alternatives proposed and the tradeoffs involved.

  7. Qual o Papel da Escola e da Mídia na Obtenção dos Conhecimentos Astronômicos?

    NASA Astrophysics Data System (ADS)

    da Cunha, W. S.; Voelzke, M. R.; Amaral, L. H.

    2007-08-01

    É amplamente reconhecido que as pessoas em geral têm grande fascínio e interesse pela Astronomia. Por outro lado, o conteúdo dessa área incluído no ensino formal está longe de ser abrangente e suficiente para suprir a demanda. Esse interesse permite aperfeiçoar a divulgação e o ensino não formal de Astronomia através da mídia aliando a adequação do conteúdo à expectativa das pessoas. A reforma do Currículo Básico da Escola Pública da maioria dos Estados brasileiros tem introduzido Astronomia desde a pré-escola até o Ensino Médio. Num estudo realizado com 1180 alunos do Ensino Médio de seis escolas estaduais, revelou-se através da aplicação de um formulário contendo questões que abordavam conhecimentos básicos em Astronomia, como foram adquiridos tais conhecimentos e à infra-estrutura da escola. Para 66,1% dos entrevistados o professor já fez alguma apresentação a respeito de Astronomia. O presente estudo revelou também que 54,4% dos alunos entrevistados adquiriram seus conhecimentos astronômicos na escola, 18,4% através da televisão e 27,1% afirmaram que seus conhecimentos foram obtidos através de outros tipos de mídia (internet, livros didáticos, filmes e revistas). Embora o estudo revele claramente que há certo equilíbrio no meio em que os alunos obtiveram seus conhecimentos astronômicos, a mídia busca não somente sua difusão, mas a disponibilização desse conhecimento de maneira correta, que às vezes, não é atingido, apresentando conceitos sem fundamentação e incorretos. Por outro lado, no dia-a-dia escolar, é comum encontrar professores que vêm para as aulas com concepções prévias, que podem diferir substancialmente das idéias a serem ensinadas, dificultando o aprendizado de futuros conceitos científicos. Uma avaliação criteriosa, avaliando as dificuldades dos professores em determinar o sentido correto dos conceitos e observando a metodologia que utilizam no ensino, poderá proporcionar uma melhor

  8. Mycobacterium tuberculosis growth following aerobic expression of the DosR regulon.

    PubMed

    Minch, Kyle; Rustad, Tige; Sherman, David R

    2012-01-01

    The Mycobacterium tuberculosis regulator DosR is induced by multiple stimuli including hypoxia, nitric oxide and redox stress. Overlap of these stimuli with conditions thought to promote latency in infected patients fuels a model in which DosR regulon expression is correlated with bacteriostasis in vitro and a proxy for latency in vivo. Here, we find that inducing the DosR regulon to wildtype levels in aerobic, replicating M. tuberculosis does not alter bacterial growth kinetics. We conclude that DosR regulon expression alone is insufficient for bacterial latency, but rather is expressed during a range of growth states in a dynamic environment.

  9. DosS Is required for the complete virulence of mycobacterium tuberculosis in mice with classical granulomatous lesions.

    PubMed

    Gautam, Uma S; McGillivray, Amanda; Mehra, Smriti; Didier, Peter J; Midkiff, Cecily C; Kissee, Ryan S; Golden, Nadia A; Alvarez, Xavier; Niu, Tianhua; Rengarajan, Jyothi; Sherman, David R; Kaushal, Deepak

    2015-06-01

    Mycobacterium tuberculosis (Mtb) must counter hypoxia within granulomas to persist. DosR, in concert with sensor kinases DosS and DosT, regulates the response to hypoxia. Yet Mtb lacking functional DosR colonize the lungs of C57Bl/6 mice, presumably owing to the lack of organized lesions with sufficient hypoxia in that model. We compared the phenotype of the Δ-dosR, Δ-dosS, and Δ-dosT mutants to Mtb using C3HeB/FeJ mice, an alternate mouse model where lesions develop hypoxia. C3HeB/FeJ mice were infected via aerosol. The progression of infection was analyzed by tissue bacterial burden and histopathology. A measure of the comparative global immune responses was also analyzed. Although Δ-dosR and Δ-dosT grew comparably to wild-type Mtb, Δ-dosS exhibited a significant defect in bacterial burden and pathology in vivo, accompanied by ablated proinflammatory response. Δ-dosS retained the ability to induce DosR. The Δ-dosS mutant was also attenuated in murine macrophages ex vivo, with evidence of reduced expression of the proinflammatory signature. Our results show that DosS, but not DosR and DosT, is required by Mtb to survive in C3HeB/FeJ mice. The attenuation of Δ-dosS is not due to its inability to induce the DosR regulon, nor is it a result of the accumulation of hypoxia. That the in vivo growth restriction of Δ-dosS could be mimicked ex vivo suggested sensitivity to macrophage oxidative burst. Anoxic caseous centers within tuberculosis lesions eventually progress to cavities. Our results provide greater insight into the molecular mechanisms of Mtb persistence within host lungs.

  10. America Inc.: John Dos Passos'"USA" as Professional Writing Textbook.

    ERIC Educational Resources Information Center

    Di Renzo, Anthony

    While working as a special consultant for General Mills in 1948, John Dos Passos wrote a report explaining the latest scientific research and technological advancements and how the postwar economy was affecting General Mills and the cereal market. General Mills, using a real writer for a corporate freelance, profited from Dos Passos' expertise and…

  11. Investigação dos perfís temporais de alta resolução de explosões solares tipo-III decimétricas

    NASA Astrophysics Data System (ADS)

    Cecatto, J. R.; Fernandes, F. C. R.; Sawant, H. S.; Madsen, F. R. H.

    2003-08-01

    Explosões solares tipo-III indicam a presença de feixes de elétrons acelerados durante "flares" solares. Sua investigação fornece informações tanto sobre os processos de aceleração de partículas quanto das características do agente causador e do local de aceleração. Explosões tipo-III decimétricas são geradas por feixes de elétrons viajando através de arcos magnéticos densos da baixa coroa solar. Os perfís temporais destes fenômenos, quando tomados com alta resolução, informam sobre os mecanismos de aceleração de partículas do feixe e o meio de transporte da energia liberada a partir da região de aceleração. Usando o Brazilian Solar Spectroscope (BSS), em operação no INPE, foram registradas dezenas de explosões tipo-III decimétricas, dentro da faixa de 2050-2250 MHz com alta resolução temporal (20 ms), em 13 de setembro de 2001, entre 13:00 e 16:10 UT. Foram selecionadas 10 explosões isoladas para uma investigação estatística detalhada de seus perfís temporais, em todos os cerca de 50 canais de freqüência. Os resultados indicam que cerca de 70% dos perfís temporais são complexos tanto durante a subida quanto descida. Os 30% restantes indicam que os perfís da subida podem ser bem representados, na maioria dos casos, por um processo não-linear e uma parcela significativa por processos lineares. Os perfís temporais da descida são dominados por um decaimento não-linear. Neste trabalho, será efetuada uma análise dos perfís temporais, tanto durante a subida quanto descida do fluxo, para as explosões selecionadas, em termos dos prováveis mecanismos de aceleração e relaxamento. 2

  12. Unique Regulation of the DosR Regulon in the Beijing Lineage of Mycobacterium tuberculosis.

    PubMed

    Domenech, Pilar; Zou, Jason; Averback, Alexandra; Syed, Nishath; Curtis, Daniele; Donato, Samuel; Reed, Michael B

    2017-01-15

    The DosR regulon, a set of 48 genes normally expressed in Mycobacterium tuberculosis under conditions that inhibit aerobic respiration, is controlled via the DosR-DosS/DosT two-component system. While the regulon requires induction in most M. tuberculosis isolates, for members of the Beijing lineage, its expression is uncoupled from the need for signaling. In our attempts to understand the mechanistic basis for this uncoupling in the Beijing background, we previously reported the identification of two synonymous single-nucleotide polymorphisms (SNPs) within the adjacent Rv3134c gene. In the present study, we have interrogated the impact of these SNPs on dosR expression in wild-type strains, as well as a range of dosR-dosS-dosT mutants, for both Beijing and non-Beijing M. tuberculosis backgrounds. In this manner, we have unequivocally determined that the C601T dosR promoter SNP is the sole requirement for the dramatic shift in the pattern of DosR regulon expression seen in this globally important lineage. Interestingly, we also show that DosT is completely nonfunctional within these strains. Thus, a complex series of evolutionary steps has led to the present-day Beijing DosR phenotype that, in turn, potentially confers a fitness advantage in the face of some form of host-associated selective pressure. Mycobacterium tuberculosis strains of the Beijing lineage have been described as being of enhanced virulence compared to other lineages, and in certain regions, they are associated with the dramatic spread of multidrug-resistant tuberculosis (TB). In terms of trying to understand the functional basis for these broad epidemiological phenomena, it is interesting that, in contrast to the other major lineages, the Beijing strains all constitutively overexpress members of the DosR regulon. Here, we identify the mutational events that led to the evolution of this unique phenotype. In addition, our work highlights the fact that important phenotypic differences exist between

  13. The DosR regulon of M. tuberculosis and antibacterial tolerance

    PubMed Central

    Bartek, I.L.; Rutherford, R.; Gruppo, V.; Morton, R.A.; Morris, R.P.; Klein, M.R.; Visconti, K.C.; Ryan, G.J.; Schoolnik, G.K.; Lenaerts, A.; Voskuil, M.I.

    2009-01-01

    Summary Adaptation of Mycobacterium tuberculosis to an anaerobic dormant state that is tolerant to several antibacterials is mediated largely by a set of highly expressed genes controlled by DosR. A DosR mutant was constructed to investigate whether the DosR regulon is involved in antibacterial tolerance. We demonstrate that induction of the regulon is not required for drug tolerance either in vivo during a mouse infection or in vitro during anaerobic dormancy. Thus, drug tolerance observed in these models is due to other mechanisms such as the bacilli simply being in a non-replicating or low metabolic state. Our data also demonstrate that the DosR regulon is not essential for virulence during chronic murine infection. However, decreased lung pathology was observed in the DosR mutant. We also show that the DosR regulon genes are more highly conserved in environmental mycobacteria, than in pathogenic mycobacteria lacking a latent phase or environmental reservoir. It is possible that the DosR regulon could contribute to drug tolerance in human infections; however, it is not the only mechanism and not the primary mechanism for tolerance during a mouse infection. These data suggest that the regulon evolved not for pathogenesis or drug tolerance but for adaptation to anaerobic conditions in the environment and has been adapted by M. tuberculosis for survival during latent infection. PMID:19577518

  14. The Rio dos Sinos watershed: an economic and social space and its interface with environmental status.

    PubMed

    Figueiredo, J A S; Drumm, E; Rodrigues, M A S; Spilki, F R

    2010-12-01

    The Rio dos Sinos watershed is located in the eastern region of the state of Rio Grande do Sul and includes 32 municipalities. These municipalities develop several different economic activities such as farming and livestock along the 190 km length of the Rio dos Sinos, one of the rivers with the worst quality of water in Brazil. The region is also characterised by growing urbanisation and heavy industrialisation. The main economic activity is the leather and footwear industry. This diversified land use puts the Rio dos Sinos watershed at risk of a wide range of potential environmental impacts. The aim of the present article is to discuss the socioeconomic process currently implemented in the Rio dos Sinos watershed and the effect of these human actions on the environmental quality described throughout this special issue of the Brazilian Journal of Biology.

  15. DosR-regulon genes induction in Mycobacterium bovis BCG under aerobic conditions.

    PubMed

    Flores Valdez, Mario Alberto; Schoolnik, Gary K

    2010-05-01

    In this report we demonstrated that under aerobic conditions, Mycobacterium bovis BCG expressing an hsp60-driven second copy of the hypoxia-related transcriptional regulator DosR increased 2-fold or greater the expression of 38 out of the 48 genes belonging to the DosR regulon, including the latency antigens Rv1733c, Rv2029, Rv2627, and Rv2628. Expression of DosR under these conditions slightly delayed in vitro growth, but did not promote a non-replicating state as opposed to microaerobic and hypoxic adaptation. Our results suggest BCG producing DosR can be cultured under standard in vitro conditions, allowing evaluation of this strain as a latency-specific vaccine candidate.

  16. Linking Social Media Reports to Network Indicators of DoS Attacks

    DTIC Science & Technology

    2015-02-15

    reporting in fast-paced social media such as Twitter, but these reports are rarely linked to quantiable network behavior. A data set of network-based...FEB 2015 2. REPORT TYPE N/A 3. DATES COVERED 4. TITLE AND SUBTITLE Linking Social Media Reports to Network Indicators of DoS Attacks 5a...Random sample of 30 (D, E) pairs yielding 21 unique entities (E) Linking Social Media Reports to Network Indicators of DoS Attacks Evan Wright

  17. Measurements of degree of sensitization (DoS) in aluminum alloys using EMAT ultrasound.

    PubMed

    Li, Fang; Xiang, Dan; Qin, Yexian; Pond, Robert B; Slusarski, Kyle

    2011-07-01

    Sensitization in 5XXX aluminum alloys is an insidious problem characterized by the gradual formation and growth of beta phase (Mg(2)Al(3)) at grain boundaries, which increases the susceptibility of alloys to intergranular corrosion (IGC) and intergranular stress-corrosion cracking (IGSCC). The degree of sensitization (DoS) is currently quantified by the ASTM G67 Nitric Acid Mass Loss Test, which is destructive and time consuming. A fast, reliable, and non-destructive method for rapid detection and the assessment of the condition of DoS in AA5XXX aluminum alloys in the field is highly desirable. In this paper, we describe a non-destructive method for measurements of DoS in aluminum alloys with an electromagnetic acoustic transducer (EMAT). AA5083 aluminum alloy samples were sensitized at 100°C with processing times varying from 7days to 30days. The DoS of sensitized samples was first quantified with the ASTM 67 test in the laboratory. Both ultrasonic velocity and attenuation in sensitized specimens were then measured using EMAT and the results were correlated with the DoS data. We found that the longitudinal wave velocity was almost a constant, independent of the sensitization, which suggests that the longitudinal wave can be used to determine the sample thickness. The shear wave velocity and especially the shear wave attenuation are sensitive to DoS. Relationships between DoS and the shear velocity, as well as the shear attenuation have been established. Finally, we performed the data mining to evaluate and improve the accuracy in the measurements of DoS in aluminum alloys with EMAT. Copyright © 2010 Elsevier B.V. All rights reserved.

  18. DataPlus™ - a revolutionary applications generator for DOS hand-held computers

    Treesearch

    David Dean; Linda Dean

    2000-01-01

    DataPlus allows the user to easily design data collection templates for DOS-based hand-held computers that mimic clipboard data sheets. The user designs and tests the application on the desktop PC and then transfers it to a DOS field computer. Other features include: error checking, missing data checks, and sensor input from RS-232 devices such as bar code wands,...

  19. Dos, a heme-binding PAS protein from Escherichia coli, is a direct oxygen sensor.

    PubMed

    Delgado-Nixon, V M; Gonzalez, G; Gilles-Gonzalez, M A

    2000-03-14

    A direct sensor of O(2), the Dos protein, has been found in Escherichia coli. Previously, the only biological sensors known to respond to O(2) by direct and reversible binding were the FixL proteins of Rhizobia. A heme-binding region in Dos is 60% homologous to the O(2)-sensing PAS domain of the FixL protein, but the remainder of Dos does not resemble FixL. Specifically, the C-terminal domain of Dos, presumed to be a regulatory partner that couples to its heme-binding domain, is not a histidine kinase but more closely resembles a phosphodiesterase. The absorption spectra of Dos indicate that both axial positions of the heme iron are coordinated to side chains of the protein. Nevertheless, O(2) and CO bind to Dos with K(d) values of 13 and 10 microM, respectively, indicating a strong discrimination against CO binding. Association rate constants for binding of O(2) (3 mM(-)(1) s(-)(1)), CO (1 mM(-)(1) s(-)(1)) and even NO (2 mM(-)(1) s(-)(1)) are extraordinarily low and very similar. Displacement of an endogenous ligand, probably Met 95, from the heme iron in Dos triggers a conformational change that alters the activity of the enzymatic domain. This sensing mechanism differs from that of FixL but resembles that of the CO sensor CooA of Rhodospirillum rubrum. Overall the results provide evidence for a heme-binding subgroup of PAS-domain proteins whose working range, signaling mechanisms, and regulatory partners can vary considerably.

  20. Non-invasive tissue temperature measurements based on quantitative diffuse optical spectroscopy (DOS) of water.

    PubMed

    Chung, S H; Cerussi, A E; Merritt, S I; Ruth, J; Tromberg, B J

    2010-07-07

    We describe the development of a non-invasive method for quantitative tissue temperature measurements using Broadband diffuse optical spectroscopy (DOS). Our approach is based on well-characterized opposing shifts in near-infrared (NIR) water absorption spectra that appear with temperature and macromolecular binding state. Unlike conventional reflectance methods, DOS is used to generate scattering-corrected tissue water absorption spectra. This allows us to separate the macromolecular bound water contribution from the thermally induced spectral shift using the temperature isosbestic point at 996 nm. The method was validated in intralipid tissue phantoms by correlating DOS with thermistor measurements (R=0.96) with a difference of 1.1+/-0.91 degrees C over a range of 28-48 degrees C. Once validated, thermal and hemodynamic (i.e. oxy- and deoxy-hemoglobin concentration) changes were measured simultaneously and continuously in human subjects (forearm) during mild cold stress. DOS-measured arm temperatures were consistent with previously reported invasive deep tissue temperature studies. These results suggest that DOS can be used for non-invasive, co-registered measurements of absolute temperature and hemoglobin parameters in thick tissues, a potentially important approach for optimizing thermal diagnostics and therapeutics.

  1. Non-invasive tissue temperature measurements based on quantitative diffuse optical spectroscopy (DOS) of water

    PubMed Central

    Chung, SH; Cerussi, AE; Merritt, SI; Ruth, J; Tromberg, BJ

    2012-01-01

    We describe the development of a non-invasive method for quantitative tissue temperature measurements using Broadband diffuse optical spectroscopy (DOS). Our approach is based on well-characterized opposing shifts in near-infrared (NIR) water absorption spectra that appear with temperature and macromolecular binding state. Unlike conventional reflectance methods, DOS is used to generate scattering-corrected tissue water absorption spectra. This allows us to separate the macromolecular bound water contribution from the thermally induced spectral shift using the temperature isosbestic point at 996 nm. The method was validated in intralipid tissue phantoms by correlating DOS with thermistor measurements (R = 0.96) with a difference of 1.1 ± 0.91 °C over a range of 28–48 °C. Once validated, thermal and hemodynamic (i.e. oxy- and deoxy-hemoglobin concentration) changes were measured simultaneously and continuously in human subjects (forearm) during mild cold stress. DOS-measured arm temperatures were consistent with previously reported invasive deep tissue temperature studies. These results suggest that DOS can be used for non-invasive, co-registered measurements of absolute temperature and hemoglobin parameters in thick tissues, a potentially important approach for optimizing thermal diagnostics and therapeutics. PMID:20551502

  2. Earth and Heavens: Two Separate Universes? (Spanish Title: Tierra y Cielos: ¿Dos Universos Separados?) Terra e Céus: Dois Universos Separados?

    NASA Astrophysics Data System (ADS)

    Carrascosa, Jaime; Gil-Pérez, Daniel; Solbes, Jordi; Vilches, Amparo

    2005-12-01

    complexidade, considerando, entre outros aspectos: as situações problemáticas relevantes que levaram à construção dos conhecimentos, as dificuldades de todo tipo que se teve que enfrentar nessa construção e, muito em particular,a necessidade de se superar as "evidências do senso comum" que estabeleciam uma suposta barreira intransponível entre a Terra e os Céus e que foram um obstáculo durante séculos para o desenvolvimento científico. Neste trabalho apresentamos um programa de atividades para o estudo da gravitação nos últimos anos do ensino médio, orientado a favorecer a participação dos estudantes, em alguma medida, na reconstrução deste processo que constituiu a denominada primeira grande revolução científica e a nos aproximarmos do estudo de uma das ciências mais antigas, a Astronomia, que hoje continua despertando grande interesse.

  3. Documenting 35 years of land cover change: Lago Cachet Dos drainage, Chile

    USGS Publications Warehouse

    Friesen, Beverly A.; Nimick, David A.; Mcgrath, Daniel; Cole, Christopher J.; Wilson, Earl M.; Noble, Suzanne M.; Fahey, Mark J.; Leidich, Jonathan; O'Kuinghttons Villena, Jorge I.

    2015-01-01

    The U.S. Geological Survey (USGS) Special Applications Science Center is monitoring temporal changes at the Colonia Glacier and Lago Cachet Dos, Northern Patagonia Icefield of southern Chile. This location is one of the newest international sites in the USGS Global Fiducial Program (GFP)—a program which provides systematic monitoring of dynamic and environmentally critical areas with high-resolution imagery (http://gfp.usgs.gov/). In 2008, Lago Cachet Dos began experiencing glacial lake outburst floods (GLOFs) during which the entire pool of water (about 200 million cubic meters) rapidly drains from the lake and flows south-southeast through the Colonia Glacier. These catastrophic events cause massive erosion of valley-fill deposits and consequent upstream expansion of Lago Cachet Dos towards Lago Cachet Uno.  Panchromatic and multispectral images for 1979, 2007, and 2014 highlight the dramatic changes that have occurred at this site over a 35-year period. The lake was smallest in 1979, when the Colonia Glacier was at its maximum extent during the study period. Between 1979 and 2007, the glacier shrank causing an increase in the surface area of the lake. The size of the lake increased substantially, from 2.98 square kilometers (km2) in 1979 to 4.41 km2 in 2014, primarily due to erosion of valley-fill deposits upstream of its northern edge by the 15 GLOFs that occurred between April 2008 and February 2014. Ongoing studies of the Colonia Glacier and Lago Cachet Dos are focused on providing real-time monitoring of Lago Cachet Dos lake levels, understanding the history of advances and retreats of the Colonia Glacier, and determining the physical mechanisms and hazards associated with the GLOFs that come from Lago Cachet Dos.

  4. WE-E-BRB-10: DosCheck - an Electronic Chart Checking Tool for Dosimetrists.

    PubMed

    Yang, D; Wu, Y; Yaddanapudi, S; Moore, K; Pierbuxg, B; Brame, S; Mutic, S

    2012-06-01

    In addition to treatment planning, dosimetrists have to prepare documentation and manually enter data in treatment management system (TMS) which did not transfer or setup automatically. The required documents and data are dependent on the disease site, treatment machine and clinical workflow. Errors and inconsistencies can cause redundant work, treatment delays and potentially treatment errors. To address these issues, an electronic checking software tool, DosCheck was clinically implemented to check the existence of necessary documentations and the integrity of manually-entered data. The purpose of this software is to reduce the frequency of human errors and to improve efficiency. DosCheck reads data and documents from 1) TMS, 2) Pinnacle TPS, and 3) DICOM plan files stored in a DICOM-RT PACS. It processes documents in Word and PDF format, treatment plan data in Pinnacle native format and DICOM format, and Mosaiq data in database records. The software cross-checks data accuracy and consistency by following rules that are pre-defined according to the clinical requirements and treatment sties. It interacts with dosimetrists and presents instantaneous results via graphical user interface. DosCheck has been implemented in C#. It performs a full check for a patient with 20 seconds. It has been clinically commissioned and is used daily by all dosimetrists at our institution. Retrospective analysis shows that DosCheck identifies 30% to 40% of previously reported dosimetrist human errors. Additional ∼30% errors are checked by other tools that could be integrated DosCheck in the near future. As an electronic data checking tool, DosCheck can obtain and process data and documents from multiple clinical computer systems in the radiation oncology department, and perform checks according to clinical rules. It is able to improve the accuracy and efficiency of clinical data and document process, and therefore to reduce any potential inconsistencies and errors. © 2012 American

  5. Reagent based DOS: a "Click, Click, Cyclize" strategy to probe chemical space.

    PubMed

    Rolfe, Alan; Lushington, Gerald H; Hanson, Paul R

    2010-05-07

    The synthesis of small organic molecules as probes for discovering new therapeutic agents has been an important aspect of chemical-biology. Herein we report a reagent-based, diversity-oriented synthetic (DOS) strategy to probe chemical and biological space via a "Click, Click, Cyclize" protocol. In this DOS approach, three sulfonamide linchpins underwent cyclization protocols with a variety of reagents to yield a collection of structurally diverse S-heterocycles. In silico analysis is utilized to evaluate the diversity of the compound collection against chemical space (PC analysis), shape space (PMI) and polar surface area (PSA) calculations.

  6. Meio-Socks & Other Genetic Yarns

    ERIC Educational Resources Information Center

    Stravroulakis, Anthea M.

    2005-01-01

    As a teacher, the author is always interested in novel pedagogical methods for presenting complex concepts and material in genetics that interest and engage the students, while helping them understand and recall the lesson. In this article, she describes sock and yarn models that allow students the opportunity to examine the meiotic process in a…

  7. Meio-Socks & Other Genetic Yarns

    ERIC Educational Resources Information Center

    Stravroulakis, Anthea M.

    2005-01-01

    As a teacher, the author is always interested in novel pedagogical methods for presenting complex concepts and material in genetics that interest and engage the students, while helping them understand and recall the lesson. In this article, she describes sock and yarn models that allow students the opportunity to examine the meiotic process in a…

  8. Sedimentation survey of Lago Dos Bocas, Utuado, Puerto Rico, January 2010

    USGS Publications Warehouse

    Soler-López, Luis R.

    2014-01-01

    Lago Dos Bocas reservoir was completed in 1942 to provide water for hydroelectric power generation along the northern coast of Puerto Rico. The reservoir had an original storage capacity of 37.50 million cubic meters (Mm3). The dam is located about 9 kilometers (km) northeast of the town of Utuado, immediately downstream of the original confluence of the Río Grande de Arecibo and the Río Caonillas (fig. 1). The Puerto Rico Electric Power Authority (PREPA) owns and operates the Lago Dos Bocas reservoir, and since 1996, the reservoir has become an essential part of the Puerto Rico Aqueduct and Sewer Authority (PRASA) North Coast Superaqueduct Project. The Superaqueduct is supplied by controlled releases for hydroelectric power generation that replenish the public-supply raw-water intake pool located about 10 km downstream from the Lago Dos Bocas Dam (fig. 1). As of 2005, the Superaqueduct supplies about 4.03 cubic meters per second (m3/s) (348,192 cubic meters per day [m3/d]) of potable water to communities along the northern coast, from Arecibo to the San Juan metropolitan area. Because of the importance of the reservoir to the North Coast Superaqueduct, the U.S. Geological Survey (USGS), in cooperation with PRASA, conducted a sedimentation survey of Lago Dos Bocas in January 2009. The results of this survey were used to estimate the useful life and the firm yield of the reservoir, and evaluate the need to dredge the reservoir.

  9. Content Analysis Schedule for Bilingual Education Programs: Programa en Dos Lenguas.

    ERIC Educational Resources Information Center

    Ludanyi, R. P.; Shore, Marietta Saravia

    This content analysis schedule for the "Programa en Dos Lenguas" of Fort Worth, Texas, presents information on the history, funding, and scope of the project. Included are sociolinguistic process variables such as the native and dominant languages of students and their interaction. Information is provided on staff selection and the…

  10. Function, regulation and pathological roles of the Gab/DOS docking proteins

    PubMed Central

    2009-01-01

    Since their discovery a little more than a decade ago, the docking proteins of the Gab/DOS family have emerged as important signalling elements in metazoans. Gab/DOS proteins integrate and amplify signals from a wide variety of sources including growth factor, cytokine and antigen receptors as well as cell adhesion molecules. They also contribute to signal diversification by channelling the information from activated receptors into signalling pathways with distinct biological functions. Recent approaches in protein biochemistry and systems biology have revealed that Gab proteins are subject to complex regulation by feed-forward and feedback phosphorylation events as well as protein-protein interactions. Thus, Gab/DOS docking proteins are at the centre of entire signalling subsystems and fulfil an important if not essential role in many physiological processes. Furthermore, aberrant signalling by Gab proteins has been increasingly linked to human diseases from various forms of neoplasia to Alzheimer's disease. In this review, we provide a detailed overview of the structure, effector functions, regulation and evolution of the Gab/DOS family. We also summarize recent findings implicating Gab proteins, in particular the Gab2 isoform, in leukaemia, solid tumours and other human diseases. PMID:19737390

  11. Pygmy Rice Rat as Potential Host of Castelo dos Sonhos Hantavirus

    PubMed Central

    Travassos da Rosa, Elizabeth S.; Medeiros, Daniele B. A.; Nunes, Márcio R.T.; Simith, Darlene B.; Pereira, Armando de Souza; Elkhoury, Mauro R.; Lavocat, Marília; Marques, Aparecido A.R.; Via, Alba Valéria; D’Andrea, Paulo; Bonvicino, Cibele R.; Lemos, Elba Regina S.

    2011-01-01

    To study the dynamics of wild rodent populations and identify potential hosts for hantavirus, we conducted an eco-epidemiologic study in Campo Novo do Parecis, Mato Grosso State, Brazil. We detected and genetically characterized Castelo dos Sonhos virus found in a species of pygmy rice rat (Oligoryzomys utiaritensis). PMID:21801642

  12. 33 CFR 106.250 - Declaration of Security (DoS).

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 33 Navigation and Navigable Waters 1 2012-07-01 2012-07-01 false Declaration of Security (DoS). 106.250 Section 106.250 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY MARITIME SECURITY MARINE SECURITY: OUTER CONTINENTAL SHELF (OCS) FACILITIES Outer Continental Shelf...

  13. 33 CFR 106.250 - Declaration of Security (DoS).

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 33 Navigation and Navigable Waters 1 2013-07-01 2013-07-01 false Declaration of Security (DoS). 106.250 Section 106.250 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY MARITIME SECURITY MARINE SECURITY: OUTER CONTINENTAL SHELF (OCS) FACILITIES Outer Continental Shelf...

  14. 33 CFR 106.250 - Declaration of Security (DoS).

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 33 Navigation and Navigable Waters 1 2014-07-01 2014-07-01 false Declaration of Security (DoS). 106.250 Section 106.250 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY MARITIME SECURITY MARINE SECURITY: OUTER CONTINENTAL SHELF (OCS) FACILITIES Outer Continental Shelf...

  15. 33 CFR 106.250 - Declaration of Security (DoS).

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 33 Navigation and Navigable Waters 1 2011-07-01 2011-07-01 false Declaration of Security (DoS). 106.250 Section 106.250 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY MARITIME SECURITY MARINE SECURITY: OUTER CONTINENTAL SHELF (OCS) FACILITIES Outer Continental Shelf...

  16. 33 CFR 106.250 - Declaration of Security (DoS).

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Declaration of Security (DoS). 106.250 Section 106.250 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY MARITIME SECURITY MARINE SECURITY: OUTER CONTINENTAL SHELF (OCS) FACILITIES Outer Continental Shelf...

  17. 33 CFR 105.245 - Declaration of Security (DoS).

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...) of this section. (e) At MARSEC Levels 1 and 2, FSOs of facilities that frequently interface with the... part to implement a DoS with the VSO prior to any vessel-to-facility interface when he or she deems it...

  18. 33 CFR 105.245 - Declaration of Security (DoS).

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...) of this section. (e) At MARSEC Levels 1 and 2, FSOs of facilities that frequently interface with the... part to implement a DoS with the VSO prior to any vessel-to-facility interface when he or she deems it...

  19. Stretching the Software Dollar: MS-DOS Shareware and Public Domain Software.

    ERIC Educational Resources Information Center

    Grosch, Audrey N.

    1989-01-01

    Discusses shareware and public domain software for MS-DOS systems that are available through bulletin board systems (BBS). Problems with computer viruses are discussed; shareware available for communications, database and file management, spreadsheets, word processing, and menuing software is described; and source information for software is…

  20. Entre Dos Mundos/Between Two Worlds: Youth Violence Prevention for Acculturating Latino Families

    ERIC Educational Resources Information Center

    Smokowski, Paul R.; Bacallao, Martica

    2009-01-01

    Objective: This study evaluated the efficacy of Entre Dos Mundos/Between Two Worlds (EDM) prevention for Latino adolescents. Method: In an experimental trial to compare implementation formats, 41 Latino families were randomly assigned to EDM action-oriented skills training groups, and 47 families were randomly assigned to unstructured EDM support…

  1. Low-Budget, Cost-Effective OCR: Optical Character Recognition for MS-DOS Micros.

    ERIC Educational Resources Information Center

    Perez, Ernest

    1990-01-01

    Discusses optical character recognition (OCR) for use with MS-DOS microcomputers. Cost effectiveness is considered, three types of software approaches to character recognition are explained, hardware and operation requirements are described, possible library applications are discussed, future OCR developments are suggested, and a list of OCR…

  2. Entre Dos Mundos/Between Two Worlds: Youth Violence Prevention for Acculturating Latino Families

    ERIC Educational Resources Information Center

    Smokowski, Paul R.; Bacallao, Martica

    2009-01-01

    Objective: This study evaluated the efficacy of Entre Dos Mundos/Between Two Worlds (EDM) prevention for Latino adolescents. Method: In an experimental trial to compare implementation formats, 41 Latino families were randomly assigned to EDM action-oriented skills training groups, and 47 families were randomly assigned to unstructured EDM support…

  3. Low-Budget, Cost-Effective OCR: Optical Character Recognition for MS-DOS Micros.

    ERIC Educational Resources Information Center

    Perez, Ernest

    1990-01-01

    Discusses optical character recognition (OCR) for use with MS-DOS microcomputers. Cost effectiveness is considered, three types of software approaches to character recognition are explained, hardware and operation requirements are described, possible library applications are discussed, future OCR developments are suggested, and a list of OCR…

  4. Comparison and evaluation of atmospheric correction algorithms of QUAC, DOS, and FLAASH for HICO hyperspectral imagery

    NASA Astrophysics Data System (ADS)

    Shi, Liangliang; Mao, Zhihua; Chen, Peng; Han, Sha'ou; Gong, Fang; Zhu, Qiankun

    2016-10-01

    In order to obtain the spectral information of objects and improve the retrieval of quantitative parameters from remotely sensing data accurately on land or over water bodies, atmospheric correction is a vital step, certainly, it is also a prerequisite to hyperspectral imagery data analysis approaches. On the base of previous studies, the atmospheric correction algorithms were divided to two categories: image-based empirical and model-based correction methods. The Quick Atmospheric Correction (QUAC) and Dark Object Subtraction (DOS) methods belong to the empirical or semiempirical methods, however, the Fast Line-of-sight Atmospheric Analysis of Spectral Hypercube (FLAASH) method was developed from the radiative transfer model. In this paper, we initially evaluated the performance from Hyperspectral Imager for the Coastal Ocean (HICO) of 16 Nov 2013 using QUAC, DOS, and MODTRAN integrated in FLAASH, and compared the results of these correction methods with in situ data. The results indicate that the method of FLAASH model performs much better than DOS and QUAC in atmospheric correction for HICO hyperspectral imagery, although the DOS and QUAC method is conducted more easily and do not require inputs of complex parameters.

  5. Sedimentation History of Lago Dos Bocas, Puerto Rico, 1942-2005

    USGS Publications Warehouse

    Soler-López, Luis R.

    2007-01-01

    The Lago Dos Bocas Dam, located in the municipality of Utuado in north central Puerto Rico, was constructed in 1942 for hydroelectric power generation. The reservoir had an original storage capacity of 37.50 million cubic meters and a drainage area of 440 square kilometers. In 1948, the construction of the Lago Caonillas Dam on the Rio Caonillas branch of Lago Dos Bocas reduced the natural sediment-contributing drainage area to 310 square kilometers; therefore, the Lago Caonillas Dam is considered an effective sediment trap. Sedimentation in Lago Dos Bocas reservoir has reduced the storage capacity from 37.50 million cubic meters in 1942 to 17.26 million cubic meters in 2005, which represents a storage loss of about 54 percent. The long-term annual water-storage capacity loss rate remained nearly constant at about 320,000 cubic meters per year to about 1997. The inter-survey sedimentation rate between 1997 and 1999, however, is higher than the long-term rate at about 1.09 million cubic meters per year. Between 1999 and 2005 the rate is lower than the long-term rate at about 0.13 million cubic meters per year. The Lago Dos Bocas effective sediment-contributing drainage area had an average sediment yield of about 1,400 cubic meters per square kilometer per year between 1942 and 1997. This rate increased substantially by 1999 to about 4,600 cubic meters per square kilometer per year, probably resulting from the historical magnitude floods caused by Hurricane Georges in 1998. Recent data indicate that the Lago Dos Bocas drainage area sediment yield decreased substantially to about 570 cubic meters per square kilometer per year, which is much lower than the 1942-1997 area normalized sedimentation rate of 1,235 cubic meters per square kilometer per year. The impact of Hurricane Georges on the basin sediment yield could have been the cause of this change, since the magnitude of the floods could have nearly depleted the Lago Dos Bocas drainage area of easily erodible and

  6. 76 FR 25733 - 60-Day Notice of Proposed Information Collection: DS-7001 and DS-7005, DOS-Sponsored Academic...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-05

    ... Notice of Proposed Information Collection: DS-7001 and DS- 7005, DOS-Sponsored Academic Exchange Program... preceding submission to OMB. We are conducting this process in accordance with the Paperwork Reduction Act of 1995. Title of Information Collection: DOS-Sponsored Academic Exchange Program Application. OMB...

  7. Observational Assessment of Preschool Disruptive Behavior, Part II: Validity of the Disruptive Behavior Diagnostic Observation Schedule (DB-DOS)

    ERIC Educational Resources Information Center

    Wakschlag, Lauren S.; Briggs-Gowan, Margaret J.; Hill, Carri; Danis, Barbara; Leventhal, Bennett L.; Keenan, Kate; Egger, Helen L.; Cicchetti, Domenic; Burns, James; Carter, Alice S.

    2008-01-01

    A study is conducted to determine whether the multidomain, multicontext Disruptive Behavior Diagnostic Observation Schedule (DB-DOS) is a valid observational method for assessing disruptive behavior of preschool children. It is concluded that the DB-DOS is a valid method for a direct observational assessment of clinically significant disruptive…

  8. Observational Assessment of Preschool Disruptive Behavior, Part II: Validity of the Disruptive Behavior Diagnostic Observation Schedule (DB-DOS)

    ERIC Educational Resources Information Center

    Wakschlag, Lauren S.; Briggs-Gowan, Margaret J.; Hill, Carri; Danis, Barbara; Leventhal, Bennett L.; Keenan, Kate; Egger, Helen L.; Cicchetti, Domenic; Burns, James; Carter, Alice S.

    2008-01-01

    A study is conducted to determine whether the multidomain, multicontext Disruptive Behavior Diagnostic Observation Schedule (DB-DOS) is a valid observational method for assessing disruptive behavior of preschool children. It is concluded that the DB-DOS is a valid method for a direct observational assessment of clinically significant disruptive…

  9. 48 CFR 653.217-70 - DOS form DS-1921, Award/Modification of Interagency Acquisition Agreement.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false DOS form DS-1921, Award... Regulations System DEPARTMENT OF STATE CLAUSES AND FORMS FORMS Prescription of Forms 653.217-70 DOS form DS-1921, Award/Modification of Interagency Acquisition Agreement. As prescribed in 617.504-70(b)(5)(i), DS...

  10. Models that Teach about the Computer: AppleWorks and ProDOS, the Computer's Memory and Disk Storage.

    ERIC Educational Resources Information Center

    Niess, Margaret L.

    1989-01-01

    This final article in a series on creating models for teaching about computer memory and disk storage and retrieval focuses on AppleWorks software and the Professional Disk Operating System (ProDOS). Instructions for creating a paper model of the AppleWorks menu system and the ProDOS disk file are given. (LRW)

  11. ACONF DOS

    SciTech Connect

    Atcitty, Stanley; Butler, Paul; Symons, Phlip; & Corey, Garth

    2009-03-25

    ACONF is a system which has been developed by Sandia National Laboratories. ACONF is a system for optimizing the interaction between generator, photovoltaic system, batteries, and load in independent non-grid-tied electrical systems. It is primarily used in rural locations where running utility lines proves costly if it is possible at all. It is controlled by an Ampro PC-104 Coremodule 400 controller system. The code for this system is written in the BASIC programming language. The routine contained in this document was written originally by Phil Symons. ACONF is intended to increase the efficiency of freestanding electrical systems to increase battery life and more efficiently use generator fuel.

  12. Effect of modulation frequency bandwidth on measurement accuracy and precision for digital diffuse optical spectroscopy (dDOS)

    NASA Astrophysics Data System (ADS)

    Jung, Justin; Istfan, Raeef; Roblyer, Darren

    2014-03-01

    Near-infrared (NIR) frequency-domain Diffuse Optical Spectroscopy (DOS) is an emerging technology with a growing number of potential clinical applications. In an effort to reduce DOS system complexity and improve portability, we recently demonstrated a direct digital sampling method that utilizes digital signal generation and detection as a replacement for more traditional analog methods. In our technique, a fast analog-to-digital converter (ADC) samples the detected time-domain radio frequency (RF) waveforms at each modulation frequency in a broad-bandwidth sweep (50- 300MHz). While we have shown this method provides comparable results to other DOS technologies, the process is data intensive as digital samples must be stored and processed for each modulation frequency and wavelength. We explore here the effect of reducing the modulation frequency bandwidth on the accuracy and precision of extracted optical properties. To accomplish this, the performance of the digital DOS (dDOS) system was compared to a gold standard network analyzer based DOS system. With a starting frequency of 50MHz, the input signal of the dDOS system was swept to 100, 150, 250, or 300MHz in 4MHz increments and results were compared to full 50-300MHz networkanalyzer DOS measurements. The average errors in extracted μa and μs' with dDOS were lowest for the full 50-300MHz sweep (less than 3%) and were within 3.8% for frequency bandwidths as narrow as 50-150MHz. The errors increased to as much as 9.0% when a bandwidth of 50-100MHz was tested. These results demonstrate the possibility for reduced data collection with dDOS without critical compensation of optical property extraction.

  13. Trace Element Distribution Between Olivine and Kirschsteinite in Angra Dos Reis

    NASA Technical Reports Server (NTRS)

    Fittipaldo, M. M.; Jones, R. H.; Shearer, C. K.

    2003-01-01

    The angrites are a small and enigmatic group of basaltic achondrites that possess unique mineralogical and chemical properties. The dominant mineralogy of the seven angrite members (Angra dos Reis, LEW 86010, LEW 87051, Asuka 881371, Sahara 99555, D Orbigny, and a new Moroccan member) is fassaite, olivine, and plagioclase. Angrites display a wide range of thermal histories, with Angra dos Reis (AdoR) exhibiting a cooling history different from that of the rapidly cooled members and from LEW86010, a more slowly cooled member. AdoR could represent either a cumulate or a porphyritic igneous rock that was later altered by metamorphism. We are re-examining the thermal history of AdoR in light of the more recently described angrite members. Our emphasis is a trace element study of low-Ca olivine, which we refer to as olivine, and high-Ca olivine, which we refer to as kirschsteinite, in AdoR.

  14. Using satellite images to monitor glacial-lake outburst floods: Lago Cachet Dos drainage, Chile

    USGS Publications Warehouse

    Friesen, Beverly A.; Cole, Christopher J.; Nimick, David A.; Wilson, Earl M.; Fahey, Mark J.; McGrath, Daniel J.; Leidich, Jonathan

    2015-01-01

    During 2008–2013, 14 GLOFs were released from Lago Cachet Dos and created environmental and safety concerns for downstream residents and to infrastructure. If GLOFs and the consequent headward erosion continue, the moraine that creates Lago Cachet Uno could be destabilized and breached, and the two lakes could merge. If the two lakes become connected, the volume of future GLOFs likely would be greater and thus cause longer and (or) more extensive flooding downstream. Additional GLOFs from Lago Cachet Dos are expected in the future, and continued environmental monitoring could provide an early warning system as well as scientific information that could increase our understanding of GLOFs and their consequences. GLOFs occur in glaciated areas around the world and remote sensing technologies can allow researchers to better understand—and potentially predict—future GLOF events.

  15. Magnetic field effects on the DOS of a Kondo quantum dot coupled to LL leads

    NASA Astrophysics Data System (ADS)

    Yang, Kai-Hua; Qin, Chang-Dong; Wang, Huai-Yu; Wang, Xu

    2017-01-01

    We investigate the joint effects of a magnetic field and electron-electron interaction on the tunneling density of states (DOS) of a quantum dot coupled to the Luttinger liquid leads in the Kondo regime. We find that for intralead electron interaction, the DOS develops two peaks deviated from the origin by the Zeeman energy. With the increase of the intralead interaction, a phase transition occurs. For moderately strong interaction, the Zeeman splitting peaks develop into two dips. The splitting of the Kondo peak and dip is not symmetric with respect to up and down spins. In the limit of strong interaction the Zeeman splitting behavior disappears and there appears a power-law scaling behavior.

  16. Application of a sparse matrix design strategy to the synthesis of dos libraries.

    PubMed

    Akella, Lakshmi B; Marcaurelle, Lisa A

    2011-07-11

    We have implemented an interactive and practical sparse matrix design strategy for the synthesis of DOS libraries, which facilitates the selection of diverse library members within a user-defined range of physicochemical properties while still maintaining synthetic efficiency. The utility of this approach is illustrated with the synthesis of an 8000-membered library of stereochemically diverse medium-sized rings accessible via a build/couple/pair DOS strategy. Diverse library members were selected from a virtual library by applying the maximum dissimilarity method, while the selection of similar analogs around each diverse product was ensured by picking near neighbors algorithmically based on fingerprint comparison. Adjustable filters on compound properties, which can be tailored to suit the needs of the target biology, facilitated subset selection from the synthetically accessible compounds.

  17. A Comparison of Three LISP Interpreters for MS-DOS-Based Microcomputers

    PubMed Central

    Kahane, Stephen N.; Johannes, Richard S.

    1985-01-01

    We report a comparison of three commercially available LISP interpreters running on MS-DOS-based microcomputers. Marked differences were found between the different products' memory addressing abilities, error handling and debugging facilities. Editing tools, tutoring environments, windowing, graphic capabilities, operating system and port call facilities are also contrasted. Speed was tested via a group of LISP functions (benchmarks) that attempt to isolate list manipulation, iteration, function calling, recursion and mathematical calculation performance.

  18. Adaptive Suspicious Prevention for Defending DoS Attacks in SDN-Based Convergent Networks

    PubMed Central

    Dao, Nhu-Ngoc; Kim, Joongheon; Park, Minho; Cho, Sungrae

    2016-01-01

    The convergent communication network will play an important role as a single platform to unify heterogeneous networks and integrate emerging technologies and existing legacy networks. Although there have been proposed many feasible solutions, they could not become convergent frameworks since they mainly focused on converting functions between various protocols and interfaces in edge networks, and handling functions for multiple services in core networks, e.g., the Multi-protocol Label Switching (MPLS) technique. Software-defined networking (SDN), on the other hand, is expected to be the ideal future for the convergent network since it can provide a controllable, dynamic, and cost-effective network. However, SDN has an original structural vulnerability behind a lot of advantages, which is the centralized control plane. As the brains of the network, a controller manages the whole network, which is attractive to attackers. In this context, we proposes a novel solution called adaptive suspicious prevention (ASP) mechanism to protect the controller from the Denial of Service (DoS) attacks that could incapacitate an SDN. The ASP is integrated with OpenFlow protocol to detect and prevent DoS attacks effectively. Our comprehensive experimental results show that the ASP enhances the resilience of an SDN network against DoS attacks by up to 38%. PMID:27494411

  19. Adaptive Suspicious Prevention for Defending DoS Attacks in SDN-Based Convergent Networks.

    PubMed

    Dao, Nhu-Ngoc; Kim, Joongheon; Park, Minho; Cho, Sungrae

    2016-01-01

    The convergent communication network will play an important role as a single platform to unify heterogeneous networks and integrate emerging technologies and existing legacy networks. Although there have been proposed many feasible solutions, they could not become convergent frameworks since they mainly focused on converting functions between various protocols and interfaces in edge networks, and handling functions for multiple services in core networks, e.g., the Multi-protocol Label Switching (MPLS) technique. Software-defined networking (SDN), on the other hand, is expected to be the ideal future for the convergent network since it can provide a controllable, dynamic, and cost-effective network. However, SDN has an original structural vulnerability behind a lot of advantages, which is the centralized control plane. As the brains of the network, a controller manages the whole network, which is attractive to attackers. In this context, we proposes a novel solution called adaptive suspicious prevention (ASP) mechanism to protect the controller from the Denial of Service (DoS) attacks that could incapacitate an SDN. The ASP is integrated with OpenFlow protocol to detect and prevent DoS attacks effectively. Our comprehensive experimental results show that the ASP enhances the resilience of an SDN network against DoS attacks by up to 38%.

  20. FlexyDos3D: a deformable anthropomorphic 3D radiation dosimeter: radiation properties

    NASA Astrophysics Data System (ADS)

    De Deene, Y.; Skyt, P. S.; Hil, R.; Booth, J. T.

    2015-02-01

    Three dimensional radiation dosimetry has received growing interest with the implementation of highly conformal radiotherapy treatments. The radiotherapy community faces new challenges with the commissioning of image guided and image gated radiotherapy treatments (IGRT) and deformable image registration software. A new three dimensional anthropomorphically shaped flexible dosimeter, further called ‘FlexyDos3D’, has been constructed and a new fast optical scanning method has been implemented that enables scanning of irregular shaped dosimeters. The FlexyDos3D phantom can be actuated and deformed during the actual treatment. FlexyDos3D offers the additional advantage that it is easy to fabricate, is non-toxic and can be molded in an arbitrary shape with high geometrical precision. The dosimeter formulation has been optimized in terms of dose sensitivity. The influence of the casting material and oxygen concentration has also been investigated. The radiophysical properties of this new dosimeter are discussed including stability, spatial integrity, temperature dependence of the dosimeter during radiation, readout and storage, dose rate dependence and tissue equivalence. The first authors Y De Deene and P S Skyt made an equivalent contribution to the experimental work presented in this paper.

  1. OptaDOS: A tool for obtaining density of states, core-level and optical spectra from electronic structure codes

    NASA Astrophysics Data System (ADS)

    Morris, Andrew J.; Nicholls, Rebecca J.; Pickard, Chris J.; Yates, Jonathan R.

    2014-05-01

    We present OptaDOS, a program for calculating core-electron and low-loss electron energy loss spectra (EELS) and optical spectra along with total-, projected- and joint-density of electronic states (DOS) from single-particle eigenenergies and dipole transition coefficients. Energy-loss spectroscopy is an important tool for probing bonding within a material. Interpreting these spectra can be aided by first principles calculations. The spectra are generated from the eigenenergies through integration over the Brillouin zone. An important feature of this code is that this integration is performed using a choice of adaptive or linear extrapolation broadening methods which we show produces higher accuracy spectra than standard fixed-width Gaussian broadening. OptaDOS may be straightforwardly interfaced to any electronic structure code. OptaDOS is freely available under the GNU General Public licence from http://www.optados.org.

  2. T cell responses to DosR and Rpf proteins in actively and latently infected individuals from Colombia.

    PubMed

    Riaño, Felipe; Arroyo, Leonar; París, Sara; Rojas, Mauricio; Friggen, Annemieke H; van Meijgaarden, Krista E; Franken, Kees L M C; Ottenhoff, Tom H M; García, Luis F; Barrera, Luis F

    2012-03-01

    Mycobacterium tuberculosis DosR regulon-encoded proteins elicit strong immune T-cell responses in individuals with latent tuberculosis (LTBI). Also, resuscitation (Rpf) proteins can induce such responses. However, variations in the immunogenicity of the DosR and Rpf proteins have been observed in European and African populations, and no data are published from other geographic areas. In Colombian LTBI and patients with recently diagnosed PTB, we therefore studied the immune response to DosR, Rpf, stress, and nominal antigens from Mtb, in 7-day stimulated cultures. Three DosR (Rv1737c, Rv2029c, Rv2628c) and 2 Rpf (Rv0867 and Rv2389c) antigens were recognized most prominently on the basis of the net IFNγ production (DosR) or the percentage of responding individuals (Rpf). Results show that the selected DosR antigens induced a higher proportion of CD4-T cells producing IFNγ from LTBI, compared to pulmonary TB patients (PTB), while there were no differences in the proportion of CD8-T cells. An increased frequency of CD4, but not CD8 T-cells with a CD45RO(+)CD27(+) phenotype was observed in LTBI in response to Rv2029c, Rv0867c, and Rv2389c, compared to PTB. The levels of cytokines and chemokines in the supernatants of stimulated cells, showed that the DosR and Rpf antigens induced higher levels of IFNγ in cultures from LTBI compared to PTB, although the induced pattern of cytokines and chemokines was also antigen dependent. In summary, our results are consistent with the significant immunogenicity of Mtb DosR and Rpf antigens in LTBI individuals, and confirm and extend previously reported data from other TB affected human populations.

  3. DoS detection in IEEE 802.11 with the presence of hidden nodes

    PubMed Central

    Soryal, Joseph; Liu, Xijie; Saadawi, Tarek

    2013-01-01

    The paper presents a novel technique to detect Denial of Service (DoS) attacks applied by misbehaving nodes in wireless networks with the presence of hidden nodes employing the widely used IEEE 802.11 Distributed Coordination Function (DCF) protocols described in the IEEE standard [1]. Attacker nodes alter the IEEE 802.11 DCF firmware to illicitly capture the channel via elevating the probability of the average number of packets transmitted successfully using up the bandwidth share of the innocent nodes that follow the protocol standards. We obtained the theoretical network throughput by solving two-dimensional Markov Chain model as described by Bianchi [2], and Liu and Saadawi [3] to determine the channel capacity. We validated the results obtained via the theoretical computations with the results obtained by OPNET simulator [4] to define the baseline for the average attainable throughput in the channel under standard conditions where all nodes follow the standards. The main goal of the DoS attacker is to prevent the innocent nodes from accessing the channel and by capturing the channel’s bandwidth. In addition, the attacker strives to appear as an innocent node that follows the standards. The protocol resides in every node to enable each node to police other nodes in its immediate wireless coverage area. All innocent nodes are able to detect and identify the DoS attacker in its wireless coverage area. We applied the protocol to two Physical Layer technologies: Direct Sequence Spread Spectrum (DSSS) and Frequency Hopping Spread Spectrum (FHSS) and the results are presented to validate the algorithm. PMID:25685510

  4. DoS detection in IEEE 802.11 with the presence of hidden nodes.

    PubMed

    Soryal, Joseph; Liu, Xijie; Saadawi, Tarek

    2014-07-01

    The paper presents a novel technique to detect Denial of Service (DoS) attacks applied by misbehaving nodes in wireless networks with the presence of hidden nodes employing the widely used IEEE 802.11 Distributed Coordination Function (DCF) protocols described in the IEEE standard [1]. Attacker nodes alter the IEEE 802.11 DCF firmware to illicitly capture the channel via elevating the probability of the average number of packets transmitted successfully using up the bandwidth share of the innocent nodes that follow the protocol standards. We obtained the theoretical network throughput by solving two-dimensional Markov Chain model as described by Bianchi [2], and Liu and Saadawi [3] to determine the channel capacity. We validated the results obtained via the theoretical computations with the results obtained by OPNET simulator [4] to define the baseline for the average attainable throughput in the channel under standard conditions where all nodes follow the standards. The main goal of the DoS attacker is to prevent the innocent nodes from accessing the channel and by capturing the channel's bandwidth. In addition, the attacker strives to appear as an innocent node that follows the standards. The protocol resides in every node to enable each node to police other nodes in its immediate wireless coverage area. All innocent nodes are able to detect and identify the DoS attacker in its wireless coverage area. We applied the protocol to two Physical Layer technologies: Direct Sequence Spread Spectrum (DSSS) and Frequency Hopping Spread Spectrum (FHSS) and the results are presented to validate the algorithm.

  5. Studies of Brazilian meteorites. III - Origin and history of the Angra dos Reis achondrite

    NASA Technical Reports Server (NTRS)

    Prinz, M.; Keil, K.; Hlava, P. F.; Berkley, J. L.; Gomes, C. B.; Curvello, W. S.

    1977-01-01

    The mineral composition of the Angra dos Reis meteorite, which fell in 1869, is described. This achondrite contains phases reported in a meteorite for the first time. Petrofabric analysis shows that fassaite has a preferred orientation and lineation, which is interpreted as being due to cumulus processes, possibly the effect of post-depositional magmatic current flow or laminar flow of a crystalline mush. The mineral chemistry indicates crystallization from a highly silica-undersaturated melt at low pressure. Several aspects of the mineral composition are discussed with reference to the implications of crystallization conditions.

  6. Anaerobic Mycobacterium tuberculosis cell death stems from intracellular acidification mitigated by the DosR regulon.

    PubMed

    Reichlen, Matthew J; Leistikow, Rachel L; Scobey, Micah S; Born, Sarah E M; Voskuil, Martin I

    2017-09-05

    Mycobacterium tuberculosis (Mtb) is a strict aerobe capable of prolonged survival in the absence of oxygen. We investigated the ability of anaerobic Mtb to counter challenges to internal pH homeostasis in the absence of aerobic respiration, the primary mechanism of proton efflux for aerobic bacilli. Anaerobic Mtb populations were markedly impaired for survival under a mildly acidic pH relative to standard culture conditions. Acidic environmental pH greatly increased the susceptibility of anaerobic bacilli to collapse of proton motive force by protonophores, to antimicrobial compounds that target entry into the electron transport system, and to small organic acids with uncoupling activity. However, anaerobic bacilli exhibited high tolerance to these challenges at near neutral pH. At a slightly alkaline pH which was near the optimum intracellular pH, protonophore addition even improved long-term bacilli survival. Although anaerobic Mtb in acidic conditions maintained 40% lower ATP levels than bacilli at standard culture conditions, ATP loss alone could not explain the viability drop. Protonophores decreased ATP levels by more than 90% regardless of extracellular pH but were bactericidal only under acidic conditions, indicating anaerobic bacilli could survive extreme ATP loss provided the external pH was within viable intracellular parameters. Acidic conditions drastically decreased anaerobic survival of a DosR mutant while an alkaline environment improved survival of the DosR mutant. Together these findings indicate intracellular acidification is a primary challenge for anaerobic Mtb survival and that the DosR regulon plays a critical role in sustaining internal pH homeostasis.Importance: During infection, Mtb bacilli are prevalent in environments largely devoid of oxygen. Yet the factors that influence survival of these severely growth- and metabolically-limited bacilli remain poorly understood. We determined how anaerobic bacilli respond to fluctuations in

  7. Volcanic and structural controls of mineralization in the Dos Cabezas Mountains of southeastern Arizona

    SciTech Connect

    Drewes, H.; Klein, D.P.; Birmingham, S.D.

    1988-01-01

    A combination of geophysical, geochemical, and geological features suggests that a central part of the Dos Cabezas Mountains probably has considerable potential for blind deposits, chiefly base metals. The area exposes the root zone of a Paleocene( ) volcanic complex and its underlying granitic stocks, which were emplaced next to a major northwest-trending, much reactivated fault zone. The new data, combined with the knowledge of past mining activity in the area, lead them to propose several exploration targets that may lead to ore bodies in breccia pipes along the base of the volcanic pile and along a possible concealed fault or caldera margin.

  8. Pinch-off dynamics and dripping-onto-substrate (DoS) rheometry of complex fluids.

    PubMed

    Dinic, Jelena; Jimenez, Leidy Nallely; Sharma, Vivek

    2017-01-31

    Liquid transfer and drop formation/deposition processes involve complex free-surface flows including the formation of columnar necks that undergo spontaneous capillary-driven instability, thinning and pinch-off. For simple (Newtonian and inelastic) fluids, a complex interplay of capillary, inertial and viscous stresses determines the nonlinear dynamics underlying finite-time singularity as well as self-similar capillary thinning and pinch-off dynamics. In rheologically complex fluids, extra elastic stresses as well as non-Newtonian shear and extensional viscosities dramatically alter the nonlinear dynamics. Stream-wise velocity gradients that arise within the thinning columnar neck create an extensional flow field, and many complex fluids exhibit a much larger resistance to elongational flows than Newtonian fluids with similar shear viscosity. Characterization of pinch-off dynamics and the response to both shear and extensional flows that influence drop formation/deposition in microfluidic and printing applications requires bespoke instrumentation not available, or easily replicated, in most laboratories. Here we show that dripping-onto-substrate (DoS) rheometry protocols that involve visualization and analysis of capillary-driven thinning and pinch-off dynamics of a columnar neck formed between a nozzle and a sessile drop can be used for measuring shear viscosity, power law index, extensional viscosity, relaxation time and the most relevant processing timescale for printing. We showcase the versatility of DoS rheometry by characterizing and contrasting the pinch-off dynamics of a wide spectrum of simple and complex fluids: water, printing inks, semi-dilute polymer solutions, yield stress fluids, food materials and cosmetics. We show that DoS rheometry enables characterization of low viscosity printing inks and polymer solutions that are beyond the measurable range of commercially-available capillary break-up extensional rheometer (CaBER). We show that for high

  9. Age and isotopic relationships among the angrites Lewis Cliff 86010 and Angra dos Reis

    SciTech Connect

    Lugmair, G.W. ); Galer, S.J.G. Max-Planck-Inst. fuer Chemie, Mainz )

    1992-04-01

    Results of a wide-ranging isotopic investigation of the unique Antarctican angrite LEW-86010 (LEW) are presented, together with a reassessment of the type angrite Angra dos Reis (ADOR). The principal objectives of this study are to obtain precise radiometric ages, initial Sr isotopic compositions, and to search for the erstwhile presence of the short-lived nuclei {sup 146}Sm and {sup 26}Al via their daughter products. The isotopic compositions of Sm, U, Ca, and Ti were also measured. This allows a detailed appraisal to be made of the relations between, and the genealogy of, these two angrites.

  10. PrDOS: prediction of disordered protein regions from amino acid sequence.

    PubMed

    Ishida, Takashi; Kinoshita, Kengo

    2007-07-01

    PrDOS is a server that predicts the disordered regions of a protein from its amino acid sequence (http://prdos.hgc.jp). The server accepts a single protein amino acid sequence, in either plain text or FASTA format. The prediction system is composed of two predictors: a predictor based on local amino acid sequence information and one based on template proteins. The server combines the results of the two predictors and returns a two-state prediction (order/disorder) and a disorder probability for each residue. The prediction results are sent by e-mail, and the server also provides a web-interface to check the results.

  11. Use of Remote Sensing and Local Knowledge for Geoconservation of Regiao dos Lagos, Brazil

    NASA Astrophysics Data System (ADS)

    Avelar, S.; Vasconcelos, G.; Mansur, K. L.; Anjos, S. C.

    2013-12-01

    A series of lagoons can be found along the coastline of Rio de Janeiro, in the so-called Regiao dos Lagos. The lagoons differ in size, physicochemical, sedimentological and biological characteristics. Rare examples of litifying microbialites that produce stromatolites, the oldest fossils on Earth, can be found living in this lagoon system. The occurrence of stromatolites in the region is of great scientific interest because it enables the study of possible analogues of the earliest life on Earth. However, this region has been suffering from intense human activities and degradations. Geoconservation planning requires an assessment of the characteristics of the region and its potential threats. The primary goal of this study is to assess physical environmental changes and anthropogenic impacts over the last four decades in Regiao dos Lagos. Using a broad integrative assessment combining remote sensing, GIS, field studies and local knowledge of communities, land-cover and land-use classes were identified, as well as the main human activities impacting the environment. The seasonal and weekend tourism and urban sprawl in this coastal area of Rio de Janeiro triggers the occupation of new areas and the removal of natural vegetation, especially on lagoon margins. This disorderly occupation by an ever increasing population, with both legal and illegal constructions and the subsequent overload of the local infrastructure, e.g. increase of electrical energy consumption, volume of vehicles, pollution in air, water and soil and problems with water supply and wastewater treatment, are hastening the gradual degradation of the lake ecosystem. The main driving forces to environmental changes over the last four decades in Regiao dos Lagos were the change of dense vegetation, saline and bare soil classes into built-up areas, adding to the poor waste treatment and inadequate sewage disposal. This analysis provides a basis for a better control of anthropogenic impacts and

  12. The Intraplate Seismogenic Zone of Porto dos Gauchos in the Amazon Craton, Brazil

    NASA Astrophysics Data System (ADS)

    Barros, L. V.; Assumpcao, M. S.; Quintero, R. Q.

    2007-05-01

    The Porto dos Gauchos Seismogenic Zone (PGSZ), in the center north of Mato Grosso State, in the contact between the southern Amazonian Craton and northern Parecis Basin, represents one of the most important area of seismic activity in Brazil, with the largest magnitude ever observed in the stable continent of the South America plate (6.2 mb on January 31, 1955). Focal mechanism studies indicated a pure reverse faulting regime with compressional SHmax. oriented in SE-NW direction. After the 1955 earthquake, located in Serra do Tombador, a recurrent seismicity has been detected in Porto dos Gauchos, 100 km northeast of Serra do Tombador. No recent events have been detected in the area of the 1955 epicenter, suggesting a long recurrence time or mislocation of Serra do Tombador earthquake. The Porto dos Gauchos recurrent seismicity has been observed since 1959, when a 4.5 macroseismic estimated magnitude was felt by local inhabitants settled in that remote area two years earlier. In subsequent years, with deployment of regional stations in Brazilian Amazon region earthquakes were detected in 1981 (3.8 mb), 1989 (3.3 mb), 1993 (3.8 mb), 1996 (4.4 mb), 1997 (3.3 mb), and finally on March 10, 1998 (5.1 mb). The aftershocks of 1998 main shock were studied with a local network with up to eight 3- component stations. Such network detected more than 2500 events until December of 2002, when the network was deactivated, but only 100 were accurately located. Based on this set of events and a controlled source experiment we determined a 1-D velocity model for the area, a composite focal mechanism with P wave polarities, spectral analysis studies to estimate the source dimension, stress drop and moment magnitudes for the main shock and some others events of the set. On March 23, 2005 another shock occurred in the same seismogenic area of Porto dos Gauchos, with magnitude 4.7 to 5.0. One week later five stations were installed again to monitor the aftershock activity, detecting

  13. RighTime: A real time clock correcting program for MS-DOS-based computer systems

    NASA Technical Reports Server (NTRS)

    Becker, G. Thomas

    1993-01-01

    A computer program is described which effectively eliminates the misgivings of the DOS system clock in PC/AT-class computers. RighTime is a small, sophisticated memory-resident program that automatically corrects both the DOS system clock and the hardware 'CMOS' real time clock (RTC) in real time. RighTime learns what corrections are required without operator interaction beyond the occasional accurate time set. Both warm (power on) and cool (power off) errors are corrected, usually yielding better than one part per million accuracy in the typical desktop computer with no additional hardware, and RighTime increases the system clock resolution from approximately 0.0549 second to 0.01 second. Program tools are also available which allow visualization of RighTime's actions, verification of its performance, display of its history log, and which provide data for graphing of the system clock behavior. The program has found application in a wide variety of industries, including astronomy, satellite tracking, communications, broadcasting, transportation, public utilities, manufacturing, medicine, and the military.

  14. Quality control and assurance for validation of DOS/I measurements

    NASA Astrophysics Data System (ADS)

    Cerussi, Albert; Durkin, Amanda; Kwong, Richard; Quang, Timothy; Hill, Brian; Tromberg, Bruce J.; MacKinnon, Nick; Mantulin, William W.

    2010-02-01

    Ongoing multi-center clinical trials are crucial for Biophotonics to gain acceptance in medical imaging. In these trials, quality control (QC) and assurance (QA) are key to success and provide "data insurance". Quality control and assurance deal with standardization, validation, and compliance of procedures, materials and instrumentation. Specifically, QC/QA involves systematic assessment of testing materials, instrumentation performance, standard operating procedures, data logging, analysis, and reporting. QC and QA are important for FDA accreditation and acceptance by the clinical community. Our Biophotonics research in the Network for Translational Research in Optical Imaging (NTROI) program for breast cancer characterization focuses on QA/QC issues primarily related to the broadband Diffuse Optical Spectroscopy and Imaging (DOS/I) instrumentation, because this is an emerging technology with limited standardized QC/QA in place. In the multi-center trial environment, we implement QA/QC procedures: 1. Standardize and validate calibration standards and procedures. (DOS/I technology requires both frequency domain and spectral calibration procedures using tissue simulating phantoms and reflectance standards, respectively.) 2. Standardize and validate data acquisition, processing and visualization (optimize instrument software-EZDOS; centralize data processing) 3. Monitor, catalog and maintain instrument performance (document performance; modularize maintenance; integrate new technology) 4. Standardize and coordinate trial data entry (from individual sites) into centralized database 5. Monitor, audit and communicate all research procedures (database, teleconferences, training sessions) between participants ensuring "calibration". This manuscript describes our ongoing efforts, successes and challenges implementing these strategies.

  15. Reproductive Dynamics of Sterna hirundinacea Lesson, 1831 in Ilha dos Cardos, Santa Catarina, Brazil

    PubMed Central

    Fracasso, Hélio Augusto Alves; Branco, Joaquim Olinto; Efe, Márcio Amorim

    2014-01-01

    In this work, we intend to describe the reproductive dynamics of Sterna hirundinacea in an island from South Brazil. We studied the reproductive biology of this species in its natural environment and provide data on their growth, survival, and reproductive success in Ilha dos Cardos, Santa Catarina, South Brazil. Samplings were carried out daily on the island throughout the reproductive seasons of 2003, 2005, and 2006 and the different stages of development of the chicks were characterized according to age, length of the beak, and plumage characteristics. We provide a basic equation Lm = 167.91 (1 − e −0.062t−(−0.23)) to determine the approximate age of individuals using their body mass. The main cause of chick mortality on the island was natural (63.17% in 2003, 81.41% in 2005, and 79.96% in 2006), whereas predation contributed to mortality in a proportion of 38.83% in 2003, 18.59% in 2005, and 20.04% in 2006. The absence in the area of the chicks' main predator, Kelp gull (Larus dominicanus), the large number of chicks that reached the final stages of development, and their reproductive success demonstrate that Ilha dos Cardos is an important breeding site for the species in southern Brazil. PMID:24977100

  16. Electron spin resonance dating of megafauna from Lagoa dos Porcos, Piauí, Brazil.

    PubMed

    Kinoshita, Angela; Mayer, Elver; Ribau Mendes, Vinícius; Figueiredo, Ana Maria G; Baffa, Oswaldo

    2014-06-01

    Excavations performed at Lagoa dos Porcos site revealed a vast amount of extinct mammal fossil remains, becoming one of the richest palaeontological occurrences in the Serra da Capivara National Park region, a UNESCO World Heritage. Although anatomic and taxonomic aspects of extinct Quaternary mammals are relatively well known, chronologic information for deposits is rare. In this context, electron spin resonance (ESR) dating of megafauna samples provides important information for establishing a chronological background. This work presents the ESR dating of two teeth, one of Gomphotheriidae and other of Toxodontinae. Dose-response curves of each sample were constructed using spectra acquired with a JEOL FA-200 X-Band spectrometer resulting in equivalent dose (De) of 220 ± 40 Gy and 39 ± 2 Gy for Toxodontinae and Gomphotheriidae tooth, respectively. The conversion of De in age was made using ROSY ESR dating software resulting in 26 ± 4 and 22 ± 3 ka. These results place Lagoa dos Porcos fossil assemblage within the Late Pleistocene. These dates overlap with a period of abrupt increase in rainfall in northeast Brazil, and it is possible that this environmental change is related to the formation of this deposit.

  17. Prevalence and predictors of orthorexia nervosa among German students using the 21-item-DOS.

    PubMed

    Depa, Julia; Schweizer, Jenny; Bekers, Sandra-Kristin; Hilzendegen, Carolin; Stroebele-Benschop, Nanette

    2017-03-01

    Orthorexia nervosa (ON) describes the constant pathological preoccupation with "healthy" nutrition. The current results regarding the prevalence of ON differ widely possibly because of invalid measurement tools. This study aimed to investigate ON prevalence in a sample of German students and to examine age, gender, semester, and nutritional knowledge as potential predictors of ON by comparing nutrition science (NS) with economics (ES) students. A total of 446 university students participated in the survey (NS 188, ES 268). ON was determined using the 21-item-DOS, which is a well-constructed, validated, and reliability-tested questionnaire. Age, gender, and semester were also assessed. Of the total sample, 3.3 % were classified as having ON and 9.0 % were at risk of developing ON. Older students scored significantly higher on the subscale "avoidance of additives" compared with younger students and students of lower semester suffered significantly more often from ON than students of higher semester. In addition, comparing field of study showed no significant difference in the prevalence of ON or the risk of developing ON between female NS and ES students. However, mean values for the three DOS subscales were higher among female NS students, albeit far below values indicating pathological behavior. The prevalence of ON appears to be low in this sample of German university students. Female NS students do not seem to have higher prevalence of ON or risk of developing ON.

  18. "Las Dos Cosas," or Why Mexican American Mothers Breast-Feed, But Not for Long.

    PubMed

    Flores, Angela; Anchondo, Inés; Huang, Cindy; Villanos, MariaTeresa; Finch, Casey

    2016-01-01

    To determine why mothers in El Paso, Texas, choose to breast-feed but not exclusively and why breast-feeding duration is short. This was a cross-sectional observational study of 300, mostly Mexican American, low-income mothers delivering at a county hospital who answered questions about breast-feeding and formula feeding, sociodemographics, and health habits. Most mothers (92.6%) in our study initiated breast-feeding, but only 20.3% breast-fed exclusively at the time of hospital discharge. Most mothers (73%) self-identified as Mexicans or Mexican Americans living on the border of the United States and Mexico. Mothers in our study chose to breast-feed if they decided to breast-feed during pregnancy, had breast-fed a previous child, had support from a female relative, and had attended college. Distinctively, most mothers in our study chose "las dos cosas" or to breast-feed and formula feed together early after birth. Acculturation failed to explain the breast-feeding decisions. Mexican American mothers who decided to breast-feed during pregnancy, breast-fed another child, attended college, and enlist a female relative's breast-feeding help were more likely to choose breast-feeding exclusively. Most Mexican American low-income mothers in our study chose "las dos cosas."

  19. RighTime: A real time clock correcting program for MS-DOS-based computer systems

    NASA Technical Reports Server (NTRS)

    Becker, G. Thomas

    1993-01-01

    A computer program is described which effectively eliminates the misgivings of the DOS system clock in PC/AT-class computers. RighTime is a small, sophisticated memory-resident program that automatically corrects both the DOS system clock and the hardware 'CMOS' real time clock (RTC) in real time. RighTime learns what corrections are required without operator interaction beyond the occasional accurate time set. Both warm (power on) and cool (power off) errors are corrected, usually yielding better than one part per million accuracy in the typical desktop computer with no additional hardware, and RighTime increases the system clock resolution from approximately 0.0549 second to 0.01 second. Program tools are also available which allow visualization of RighTime's actions, verification of its performance, display of its history log, and which provide data for graphing of the system clock behavior. The program has found application in a wide variety of industries, including astronomy, satellite tracking, communications, broadcasting, transportation, public utilities, manufacturing, medicine, and the military.

  20. Crystal Structures of the Response Regulator DosR From Mycobacterium Tuberculosis Suggest a Helix Rearrangement Mechanism for Phosphorylation Activation

    SciTech Connect

    Wisedchaisri, G.; Wu, M.; Sherman, D.R.; Hol, W.G.J.

    2009-05-26

    The response regulator DosR is essential for promoting long-term survival of Mycobacterium tuberculosis under low oxygen conditions in a dormant state and may be responsible for latent tuberculosis in one-third of the world's population. Here, we report crystal structures of full-length unphosphorylated DosR at 2.2 {angstrom} resolution and its C-terminal DNA-binding domain at 1.7 {angstrom} resolution. The full-length DosR structure reveals several features never seen before in other response regulators. The N-terminal domain of the full-length DosR structure has an unexpected ({beta}{alpha}){sub 4} topology instead of the canonical ({beta}{alpha}){sub 5} fold observed in other response regulators. The linker region adopts a unique conformation that contains two helices forming a four-helix bundle with two helices from another subunit, resulting in dimer formation. The C-terminal domain in the full-length DosR structure displays a novel location of helix {alpha}10, which allows Gln199 to interact with the catalytic Asp54 residue of the N-terminal domain. In contrast, the structure of the DosR C-terminal domain alone displays a remarkable unstructured conformation for helix {alpha}10 residues, different from the well-defined helical conformations in all other known structures, indicating considerable flexibility within the C-terminal domain. Our structures suggest a mode of DosR activation by phosphorylation via a helix rearrangement mechanism.

  1. Crystal Structures of the Response Regulator DosR from Mycobacterium tuberculosis Suggest a Helix Rearrangement Mechanism for Phosphorylation Activation

    PubMed Central

    Wisedchaisri, Goragot; Wu, Meiting; Sherman, David R.; Hol, Wim G. J.

    2008-01-01

    The response regulator DosR is essential for promoting long-term survival of Mycobacterium tuberculosis under low oxygen conditions in a dormant state and may be responsible for latent tuberculosis in one third of the world’s population. Here we report crystal structures of full-length unphosphorylated DosR at 2.2 Å and its C-terminal DNA-binding domain at 1.7 Å resolution. The full-length DosR structure reveals several features never seen before in other response regulators. The N-terminal domain of the full-length DosR structure has an unexpected (βα)4 topology instead of the canonical (βα)5 fold observed in other response regulators. The linker region adopts a unique conformation which contains two helices forming a four-helix bundle with two helices from another subunit, resulting in dimer formation. The C-terminal domain in the full-length DosR structure displays a novel location of helix α10 which provides Gln199 to interact with the catalytic Asp54 residue of the N-terminal domain. In contrast, the structure of the DosR C-terminal domain alone displays a remarkable unstructured conformation for helix α10 residues different from the well-defined helical conformations in all other known structures, indicating considerable flexibility within the C-terminal domain. Our structures suggest a mode of DosR activation by phosphorylation via a helix rearrangement mechanism. PMID:18353359

  2. Observational Assessment of Preschool Disruptive Behavior, Part I: reliability of the Disruptive Behavior Diagnostic Observation Schedule (DB-DOS).

    PubMed

    Wakschlag, Lauren S; Hill, Carri; Carter, Alice S; Danis, Barbara; Egger, Helen L; Keenan, Kate; Leventhal, Bennett L; Cicchetti, Domenic; Maskowitz, Katie; Burns, James; Briggs-Gowan, Margaret J

    2008-06-01

    To examine the reliability of the Disruptive Behavior Diagnostic Observation Schedule (DB-DOS), a new observational method for assessing preschool disruptive behavior. The DB-DOS is a structured clinic-based assessment designed to elicit clinically salient behaviors relevant to the diagnosis of disruptive behavior in preschoolers. Child behavior is assessed in three interactional contexts that vary by partner (parent versus examiner) and level of support provided. Twenty-one disruptive behaviors are coded within two domains: problems in Behavioral Regulation and problems in Anger Modulation. A total of 364 referred and nonreferred preschoolers participated: interrater reliability and internal consistency were assessed on a primary sample (n = 335) and test-retest reliability was assessed in a separate sample (n = 29). The DB-DOS demonstrated good interrater and test-retest reliability. Confirmatory factor analysis demonstrated an excellent fit of the DB-DOS multidomain model of disruptive behavior. The DB-DOS is a reliable observational tool for clinic-based assessment of preschool disruptive behavior. This standardized assessment method holds promise for advancing developmentally sensitive characterization of preschool psychopathology.

  3. A Direct Method to Extract Transient Sub-Gap Density of State (DOS) Based on Dual Gate Pulse Spectroscopy.

    PubMed

    Dai, Mingzhi; Khan, Karim; Zhang, Shengnan; Jiang, Kemin; Zhang, Xingye; Wang, Weiliang; Liang, Lingyan; Cao, Hongtao; Wang, Pengjun; Wang, Peng; Miao, Lijing; Qin, Haiming; Jiang, Jun; Xue, Lixin; Chu, Junhao

    2016-06-14

    Sub-gap density of states (DOS) is a key parameter to impact the electrical characteristics of semiconductor materials-based transistors in integrated circuits. Previously, spectroscopy methodologies for DOS extractions include the static methods, temperature dependent spectroscopy and photonic spectroscopy. However, they might involve lots of assumptions, calculations, temperature or optical impacts into the intrinsic distribution of DOS along the bandgap of the materials. A direct and simpler method is developed to extract the DOS distribution from amorphous oxide-based thin-film transistors (TFTs) based on Dual gate pulse spectroscopy (GPS), introducing less extrinsic factors such as temperature and laborious numerical mathematical analysis than conventional methods. From this direct measurement, the sub-gap DOS distribution shows a peak value on the band-gap edge and in the order of 10(17)-10(21)/(cm(3)·eV), which is consistent with the previous results. The results could be described with the model involving both Gaussian and exponential components. This tool is useful as a diagnostics for the electrical properties of oxide materials and this study will benefit their modeling and improvement of the electrical properties and thus broaden their applications.

  4. A Direct Method to Extract Transient Sub-Gap Density of State (DOS) Based on Dual Gate Pulse Spectroscopy

    NASA Astrophysics Data System (ADS)

    Dai, Mingzhi; Khan, Karim; Zhang, Shengnan; Jiang, Kemin; Zhang, Xingye; Wang, Weiliang; Liang, Lingyan; Cao, Hongtao; Wang, Pengjun; Wang, Peng; Miao, Lijing; Qin, Haiming; Jiang, Jun; Xue, Lixin; Chu, Junhao

    2016-06-01

    Sub-gap density of states (DOS) is a key parameter to impact the electrical characteristics of semiconductor materials-based transistors in integrated circuits. Previously, spectroscopy methodologies for DOS extractions include the static methods, temperature dependent spectroscopy and photonic spectroscopy. However, they might involve lots of assumptions, calculations, temperature or optical impacts into the intrinsic distribution of DOS along the bandgap of the materials. A direct and simpler method is developed to extract the DOS distribution from amorphous oxide-based thin-film transistors (TFTs) based on Dual gate pulse spectroscopy (GPS), introducing less extrinsic factors such as temperature and laborious numerical mathematical analysis than conventional methods. From this direct measurement, the sub-gap DOS distribution shows a peak value on the band-gap edge and in the order of 1017-1021/(cm3·eV), which is consistent with the previous results. The results could be described with the model involving both Gaussian and exponential components. This tool is useful as a diagnostics for the electrical properties of oxide materials and this study will benefit their modeling and improvement of the electrical properties and thus broaden their applications.

  5. DOS-HEATING6: A general conduction code with nuclear heat generation derived from DOT-IV transport calculations

    SciTech Connect

    Williams, M.L.; Yuecel, A.; Nadkarny, S.

    1988-05-01

    The HEATING6 heat conduction code is modified to (a) read the multigroup particle fluxes from a two-dimensional DOT-IV neutron- photon transport calculation, (b) interpolate the fluxes from the DOT-IV variable (optional) mesh to the HEATING6 control volume mesh, and (c) fold the interpolated fluxes with kerma factors to obtain a nuclear heating source for the heat conduction equation. The modified HEATING6 is placed as a module in the ORNL discrete ordinates system (DOS), and has been renamed DOS-HEATING6. DOS-HEATING6 provides the capability for determining temperature distributions due to nuclear heating in complex, multi-dimensional systems. All of the original capabilities of HEATING6 are retained for the nuclear heating calculation; e.g., generalized boundary conditions (convective, radiative, finned, fixed temperature or heat flux), temperature and space dependent thermal properties, steady-state or transient analysis, general geometry description, etc. The numerical techniques used in the code are reviewed and the user input instructions and JCL to perform DOS-HEATING6 calculations are presented. Finally a sample problem involving coupled DOT-IV and DOS-HEATING6 calculations of a complex space-reactor configurations described, and the input and output of the calculations are listed. 10 refs., 11 figs., 6 tabs.

  6. A Direct Method to Extract Transient Sub-Gap Density of State (DOS) Based on Dual Gate Pulse Spectroscopy

    PubMed Central

    Dai, Mingzhi; Khan, Karim; Zhang, Shengnan; Jiang, Kemin; Zhang, Xingye; Wang, Weiliang; Liang, Lingyan; Cao, Hongtao; Wang, Pengjun; Wang, Peng; Miao, Lijing; Qin, Haiming; Jiang, Jun; Xue, Lixin; Chu, Junhao

    2016-01-01

    Sub-gap density of states (DOS) is a key parameter to impact the electrical characteristics of semiconductor materials-based transistors in integrated circuits. Previously, spectroscopy methodologies for DOS extractions include the static methods, temperature dependent spectroscopy and photonic spectroscopy. However, they might involve lots of assumptions, calculations, temperature or optical impacts into the intrinsic distribution of DOS along the bandgap of the materials. A direct and simpler method is developed to extract the DOS distribution from amorphous oxide-based thin-film transistors (TFTs) based on Dual gate pulse spectroscopy (GPS), introducing less extrinsic factors such as temperature and laborious numerical mathematical analysis than conventional methods. From this direct measurement, the sub-gap DOS distribution shows a peak value on the band-gap edge and in the order of 1017–1021/(cm3·eV), which is consistent with the previous results. The results could be described with the model involving both Gaussian and exponential components. This tool is useful as a diagnostics for the electrical properties of oxide materials and this study will benefit their modeling and improvement of the electrical properties and thus broaden their applications. PMID:27297030

  7. First-principle calculation of the electronic structure, DOS and effective mass TlInSe2

    NASA Astrophysics Data System (ADS)

    Ismayilova, N. A.; Orudzhev, G. S.; Jabarov, S. H.

    2017-05-01

    The electronic structure, density of states (DOS), effective mass are calculated for tetragonal TlInSe2 from first principle in the framework of density functional theory (DFT). The electronic structure of TlInSe2 has been investigated by Quantum Wise within GGA. The calculated band structure by Hartwigsen-Goedecker-Hutter (HGH) pseudopotentials (psp) shows both the valence band maximum and conduction band minimum located at the T point of the Brillouin zone. Valence band maximum at the T point and the surrounding parts originate mainly from 6s states of univalent Tl ions. Bottom of the conduction band is due to the contribution of 6p-states of Tl and 5s-states of In atoms. Calculated DOS effective mass for holes and electrons are mDOS h∗ = 0.830m e, mDOS h∗ = 0.492m e, respectively. Electron effective masses are fairly isotropic, while the hole effective masses show strong anisotropy. The calculated electronic structure, density of states and DOS effective masses of TlInSe2 are in good agreement with existing theoretical and experimental results.

  8. Age and isotopic relationships among the angrites Lewis Cliff 86010 and Angra dos Reis

    NASA Technical Reports Server (NTRS)

    Lugmair, G. W.; Galer, S. J. G.

    1992-01-01

    The paper presents results of a wide-ranging isotopic investigation of the the Antarctic angrite LEW-86010 (LEW), and reassesses the type angrite Angra dos Reis (ADOR) in order to obtain precise radiometric ages and initial Sr isotopic compositions, and to search for the erstwhile presence of the short-lived nuclei Sm-146 and Al-26 via their daughter products. The isotopic compositions of Sm, U, Ca, and Ti were measured to allow a detailed appraisal to be made of the relations between, and the geneology of, these two angrites. LEW proves to be severely contaminated with modern terrestrial Pb, which is shown to result from terrestrial weathering. Concordant Pb-Pb model ages of pyroxene separates are obtained; uranium isotopic compositions are normal within error. Overall, striking age and isotopic similarities between LEW and ADOR were found, suggesting almost simultaneous production on the same asteroid, even though recent experimental studies imply that the two are not comagmatic.

  9. Estudio dinámico de un potencial perturbador dependiente de dos parámetros

    NASA Astrophysics Data System (ADS)

    Miloni, O.; Brunini, A.

    El objeto del presente trabajo consiste en el estudio dinámico de un sistema dinámico caracterizado por la función hamiltoniana correspondiente a un satélite planetario perturbado por la acción del Sol y del achatamiento del planeta madre. Cuando dicha Hamiltoniana se promedia respecto de los términos de corto período, esta queda con dos grados de libertad, y su estudio puede ser realizado con las herramientas clásicas de la dinámica no-lineal. Se tratará de determinar regiones regulares y caóticas de movimiento. En el caso de estas últimas, es de particular interés la determinación de su orígen.

  10. On securing wireless sensor network--novel authentication scheme against DOS attacks.

    PubMed

    Raja, K Nirmal; Beno, M Marsaline

    2014-10-01

    Wireless sensor networks are generally deployed for collecting data from various environments. Several applications specific sensor network cryptography algorithms have been proposed in research. However WSN's has many constrictions, including low computation capability, less memory, limited energy resources, vulnerability to physical capture, which enforce unique security challenges needs to make a lot of improvements. This paper presents a novel security mechanism and algorithm for wireless sensor network security and also an application of this algorithm. The proposed scheme is given to strong authentication against Denial of Service Attacks (DOS). The scheme is simulated using network simulator2 (NS2). Then this scheme is analyzed based on the network packet delivery ratio and found that throughput has improved.

  11. Age and isotopic relationships among the angrites Lewis Cliff 86010 and Angra dos Reis

    NASA Technical Reports Server (NTRS)

    Lugmair, G. W.; Galer, S. J. G.

    1992-01-01

    The paper presents results of a wide-ranging isotopic investigation of the the Antarctic angrite LEW-86010 (LEW), and reassesses the type angrite Angra dos Reis (ADOR) in order to obtain precise radiometric ages and initial Sr isotopic compositions, and to search for the erstwhile presence of the short-lived nuclei Sm-146 and Al-26 via their daughter products. The isotopic compositions of Sm, U, Ca, and Ti were measured to allow a detailed appraisal to be made of the relations between, and the geneology of, these two angrites. LEW proves to be severely contaminated with modern terrestrial Pb, which is shown to result from terrestrial weathering. Concordant Pb-Pb model ages of pyroxene separates are obtained; uranium isotopic compositions are normal within error. Overall, striking age and isotopic similarities between LEW and ADOR were found, suggesting almost simultaneous production on the same asteroid, even though recent experimental studies imply that the two are not comagmatic.

  12. Measured oxygen fugacities of the Angra dos Reis achondrite as a function of temperature

    USGS Publications Warehouse

    Brett, R.; Stephen, Huebner J.; Sato, M.

    1977-01-01

    Measurements of the oxygen fugacity (f{hook}O2) as a function of temperature (T) were made on an interior bulk sample of the cumulate achondrite, Angra dos Reis. Data clustered between the f{hook}O2-T relationship of the iron-wu??stite assemblage and 1.2 log atm units above iron-wu??stite. Interpretation of the data indicates that, throughout most of the cooling history of the meteorite, f{hook}O2 values were defined by equilibria involving iron-bearing species at values close to the f{hook}O2 of the assemblage iron-wu??stite. Measured f{hook}O2 data are compatible with crystallization and cooling at pressures greater than 50 bars. ?? 1977.

  13. Revisiting DoS Attacks and Privacy in RFID-Enabled Networks

    NASA Astrophysics Data System (ADS)

    D'Arco, Paolo; Scafuro, Alessandra; Visconti, Ivan

    Vaudenay presented in [ASIACRYPT 2007] a general RFID security and privacy model that abstracts some previous works in a single, concise, and much more understandable framework. He introduced eight distinct notions of privacy, corresponding to adversaries of different strength, and proved some possibility and impossibility results for such privacy notions. However, some interesting problems as: 1) achieving stronger privacy using low-cost tags (i.e., tags that usually can not perform public-key cryptography), 2) achieving stronger privacy in presence of side-channel attacks (e.g., DoS attacks, detection of the outputs of identification protocols), and 3) achieving stronger privacy under standard complexity-theoretic assumptions, are still left open.

  14. An MS-DOS-based program for analyzing plutonium gamma-ray spectra

    SciTech Connect

    Ruhter, W.D.; Buckley, W.M.

    1989-09-07

    A plutonium gamma-ray analysis system that operates on MS-DOS-based computers has been developed for the International Atomic Energy Agency (IAEA) to perform in-field analysis of plutonium gamma-ray spectra for plutonium isotopics. The program titled IAEAPU consists of three separate applications: a data-transfer application for transferring spectral data from a CICERO multichannel analyzer to a binary data file, a data-analysis application to analyze plutonium gamma-ray spectra, for plutonium isotopic ratios and weight percents of total plutonium, and a data-quality assurance application to check spectral data for proper data-acquisition setup and performance. Volume 3 contains the software listings for these applications.

  15. The Secret List of Dos and Don'ts for Filmmaking

    NASA Astrophysics Data System (ADS)

    Kramer, N.

    2012-12-01

    Science is a massive black box to billions of people who walk the streets. However, the process of filmmaking can be equally as mystifying. As with the development of many scientific experiments, the process starts on a napkin at a restaurant…but then what? The road to scientific publication is propelled by a canonical list of several dos and don't that fit most situations. An equally useful list exists for up-and-coming producers. The list streamlines efforts, optimizes your use of the tools at your fingertips and enhances impact. Many fundamentals can be learned from books, but during this talk we will project and discuss several examples of best practices, from honing a story, to identifying audience appeal, filming, editing and the secrets of inexpensively acquiring expert help. Whether your goal is a two-minute webisode or a 90 minute documentary, these time-tested practices, with a little awareness, can give life to your films.;

  16. [Anterior cruciate ligament-plasty using the "U-dos" technique].

    PubMed

    Morales-Trevizo, C; Paz-García, M; Leal-Berumen, I; Leal-Contreras, C; Berumen-Nafarrate, E

    2013-01-01

    The knee is a compound diarthrodial joint, vulnerable to serious injuries such as ligament injuries of: medial collateral ligament, lateral collateral ligament, anterior cruciate ligament and posterior cruciate ligament, as cruciate ligaments limit rotation movement in the joint. The purpose of our study was to create a new technique to treat injuries of the anterior cruciate ligament, which is composed of two bundles--anteromedial and posterolateral--trying to achieve an anatomical reconstruction that allows for a normal biomechanical recovery. This technique reduces the use of fixation material and costs. The diagnosis of anterior cruciate ligament injuries was made with the pivot shift test. There are currently two repair methods for anterior cruciate ligament injuries: single bundle or double bundle repair; none of these techniques is considered as the gold standard, as their results are very similar. This paper describes a technique used for the treatment of anterior cruciate ligament injuries, known as "U-dos", and its clinical results. Cross-sectional, observational study that enrolled 20 patients with total anterior cruciate ligament injuries who underwent anterior cruciate ligament plasty using the "U-dos" technique between June 2009 and June 2010. The technique requires the use of bone bank allograft, in this case of the anterior tibial ligament. Patients were assessed using the Lysholm scale and the pivot shift test. Our results show that all the pivot shift tests were negative and assessments according to the Lysholm scale were from normal to excellent in 95% of cases (19/20). Only one failure was reported, with avulsion of the graft attachment which required a surgical intervention.

  17. Development of Educational Resources to Include the Teaching of Astronomy in the First Years of the Basic Education. (Spanish Title: Desarrollo de Recursos Pedagógicos Para Incluir la Enseñanza de la Astronomía en los Primeros Años de la Educación Básica.) Desenvolvimento de Recursos Pedagógicos Para Inserir o Ensino de Astronomia nas Séries Iniciais do Ensino Fundamental

    NASA Astrophysics Data System (ADS)

    da Silva Morett, Samara; de Oliveira Souza, Marcelo

    2010-07-01

    ía y la vida cotidiana de los estudiantes. La inclusión de la astronomía en la escuela primaria es una manera de demostrar a los estudiantes cómo este campo está presente de forma activa en su vida cotidiana. Las clases que participan en el proyecto participaron en un estudio con el objetivo de proporcionar información a los conocimientos previos que tenían sobre los temas de la astronomía que se examinaron durante el proyecto. Con los experimentos realizados, y la ayuda de las nuevas tecnologías, conceptos astronómicos fueron presentados a los estudiantes de 4to y 5to año de la educación básica de una escuela municipal de Campos dos Goytacazes (RJ). Después de las presentaciones nuevos datos fueran colectados y se han llevado a cabo con el fin de verificar el nivel de aprendizaje alcanzado y se observó que el método utilizado fue una herramienta importante para ayudar al proceso de enseñanza y aprendizaje. El proyecto logró resultados satisfactorios. Neste trabalho será apresentado o desenvolvimento de recursos pedagógicos para a apresentação de conceitos de astronomia nas séries iniciais do ensino fundamental. Este material é composto por apresentações realizadas com o uso de novos recursos tecnológicos, pela fabricação de experimentos e a discussão de curiosidades relativas a esta área de conhecimento. Os experimentos foram construídos com material de baixo custo com o objetivo de permitir que os alunos envolvidos pudessem refazê-los em outras ocasiões. O material apresentado busca enfatizar a relação entre a astronomia e o cotidiano dos alunos. A inclusão da astronomia no ensino fundamental e uma forma de demonstrar aoestudante como esta área está presente de forma ativa em seu cotidiano. As turmas envolvidas no projeto participaram de uma pesquisa com o objetivo de obter dados relativos ao conhecimento prévio que possuíam sobre os tópicos de astronomia que foram considerados no decorrer do projeto. Com os experimentos

  18. Creating a Global Fiducials Program (GFP) Site: Lago Cachet Dos example in Chile

    NASA Astrophysics Data System (ADS)

    Friesen, B. A.; Nimick, D. A.; Wilson, E. M.

    2012-12-01

    The USGS has been acquiring remotely sensed imagery from all over the world, collecting thousands of images at more than 200 sites, and creating Literal Image Derived Products (LIDPs) as part of the Global Fiducials Program (GFP). The GFP program enables scientists to use these images to study our rapidly changing planet at carefully selected locations around the world. New GFP Sites are created and added each year. Researchers at the University of Alaska, for instance, added areas susceptible to coastal erosion for monitoring the long-term effects of high tides and storms. This presentation will guide you through the process of creating a new GFP site for your area of interest. We will describe the components of the GFP and its archive, the Global Fiducials Library. The Global Fiducials Program—Initial Site Proposal form will be presented and we will show you how to complete each component in order to propose a new site. Lago Cachet Dos, a glacier-dammed lake in southern Chile, is currently being proposed as a new GFP site and will be used as the example for this exercise. In addition, USGS web sites will be used to illustrate how a long-term imagery record can tell a story and to demonstrate viewing and downloading the type of data that will be available online and free of charge through the GFP.

  19. A proposed application of an industrial DOS computer for distribution substation monitoring and control

    SciTech Connect

    Batur, I. . Aselsan Military); Guven, A.N.; Ozay, N. . Electrical Engineering Dept.)

    1994-04-01

    This paper presents the design and implementation of an intelligent controller intended for use in distribution substations to perform monitoring and control duties within the framework of distribution automation needs. The hardware of the developed controller is a DOS based industrial computer running on ECB-BUS. The application software handles all input/output tasks, data collection, manipulation and control decisions with its flexible structure. This embedded controller measures bus voltage, transformer and feeder currents and calculates the real and reactive power, power factor, frequency, and total harmonic distortion of voltage and current. In addition to its local and remote data acquisition and monitoring functions by means of console and SCADA outputs, the system, through its relay outputs, is capable of performing automation tasks such as integrated Volt/Var control, overload and underfrequency detection and load shedding at the substation level. This reliable, high capacity and low cost system is completely programmable so that it can handle new requirements with new configurations easily.

  20. Environmental discrimination among soft-bottom mollusc associations off Lagoa dos Patos, South Brazil

    NASA Astrophysics Data System (ADS)

    Absalão, R. S.

    1991-01-01

    Sublittoral benthic molluscs established in the outlet of Lagoa dos Patos (South Brazil) were sampled with a rectangular dredge and the malacological associations delineated by cluster analysis (WPGA) using the Baroni-Urbani and Buser similarity index. Three main associations were characterized in bands parallel to the beach with relative concordance with specific sedimentological facies. The multiple discriminant analysis showed that there was a high correlation between these associations and the following environmental parameters: depth, average grain size, skewness of the sediment, medium sand, coarse sand, total sand and total mud. The effect of reducing the multidimensionality of the data to two factors, ecologically explained, brings out the importance of depth, average grain size, total sand and total mud. The first appears to be a bathymetric gradient of stability/disturbance; the disturbance from storms becomes less frequent with increasing depth. This is partially supported by the results of the Caswell neutral model, and is in agreement with the intermediate disturbance hypothesis predictions. The second sedimentological factor is the relative percentages of sand and mud in determining the specific composition of these associations.

  1. Endocrine disruptors in water filters used in the Rio dos Sinos Basin region, Southern Brazil.

    PubMed

    Furtado, C M; von Mühlen, C

    2015-05-01

    The activated carbon filter is used in residences as another step in the treatment of drinking water, based on a physical-chemical process to absorb pollutants that are not removed in conventional treatment. Endocrine disruptors (EDCs) are exogenous substances or mixtures of substances that acts on the endocrine system similarly to the endogenously produced hormones, triggering malfunctions and harmful changes to human and animal health. The objective of the present work was to study EDCs through semi-quantitative analysis of residential water filters collected in the region of Rio dos Sinos basin, focusing on two specific classes: hormones and phenols. The solid phase extraction principle was used for the extraction of compounds and gas chromatography coupled with mass spectrometry for the separation and characterization of EDCs. Four samples of residential filters collected from public water distribution and artesian wells, from the cities of Novo Hamburgo and São Leopoldo were analysed. Using the developed methodology, it was possible to detect and comparatively quantify selected EDCs in all studied samples, which indicates the presence of these contaminants in drinking water from different sources.

  2. Urano y sus dos satélites irregulares recientemente descubiertos

    NASA Astrophysics Data System (ADS)

    Parisi, M. G.; Brunini, A.

    Hasta hace poco tiempo, Urano era el único de los Planetas Gigantes que no poseía satélites irregulares. Esto lo diferenciaba del resto de los planetas Gigantes, al igual que la peculiar oblicuidad de su eje de spin. La gran inclinación de su eje de rotación se debe probablemente a una colisión que sufrió el planeta con otro embrión planetario al final del proceso de formación. Esta colisión habría desligado satélites exteriores preexistentes del planeta. Recientemente se han descubierto dos satélites irregulares de Urano, lo que introduce algunas nuevas cotas y condiciones en el escenario de la "Hipótesis de la Gran Colisión" . Los satélites irregulares de Urano tuvieron que ser capturados en una etapa posterior a la del escenario de la Gran Colisión, de no ser así, hubieran sido eyectados del sistema por el impulso impartido con ese gran impacto. En este trabajo, se discuten los posibles mecanismos de captura de los satélites irregulares y se presenta un nuevo posible mecanismo para dicha captura.

  3. Dos and don'ts for using climate information for water resource planning and management

    NASA Astrophysics Data System (ADS)

    Vano, J. A.; Clark, M. P.; Nijssen, B.; Wood, A.; Gutmann, E. D.; Arnold, J.

    2016-12-01

    Increasingly water managers and planners are being required to incorporate climate change information into their planning processes. This is generally seen as a step in the right direction. However, the continuously evolving and expanding realm of climate information can be confusing to use and easy to apply in ways the information producers never intended, and often in ways those producers might say are not viable. Additionally, advice on how various products should be used is not usually straightforward - it may require an extended dialogue between scientists and end users, which is not always feasible with current resources. While rarely is there a one-size fits all approach, there are usually preferable paths forward. To help the water resource planning and management community navigate the ever-changing climate science landscape, we present a set of guidelines for better practices when using climate information. These are divided into two categories: (1) process-based recommendations for developing an effective approach for using climate change scenarios, and (2) product-based cautions for using climate change information. This collection of dos and don'ts provides context on why certain strategies are preferable, including real-world examples. This work is intended to provide a foundation that can be built on through dialogue within and between the climate science and application communities to increase the usefulness of climate information.

  4. Geochemical and isotopic constraints on the tectonic setting of Serra dos Carajas belt, eastern Para, Brazil

    NASA Technical Reports Server (NTRS)

    Olszewski, W. J., Jr.; Gibbs, A. K.; Wirth, K. R.

    1986-01-01

    The lower part of the Serra dos Carajas belt is the metavolcanic and metasedimentary Grao para Group (GPG). The GPG is thought to unconformably overlie the older (but undated) Xingu Complex, composed of medium and high-grade gneisses and amphibolite and greenstone belts. The geochemical data indicate that the GPG has many features in common with ancient and modern volcanic suites erupted through continental crust. The mafic rocks clearly differ from those of most Archean greenstone belts, and modern MORB, IAB, and hot-spot basalts. The geological, geochemical, and isotopic data are all consistent with deposition on continental crust, presumably in a marine basin formed by crustal extension. The isotopic data also suggest the existence of depleted mantle as a source for the parent magmas of the GPG. The overall results suggest a tectonic environment, igneous sources, and petrogenesis similar to many modern continental extensional basins, in contrast to most Archean greenstone belts. The Hammersley basin in Australia and the circum-Superior belts in Canada may be suitable Archean and Proterozoic analogues, respectively.

  5. ANALYSIS OF THE PICO DOS DIAS SURVEY HERBIG Ae/Be CANDIDATES

    SciTech Connect

    Sartori, Marilia J.; Rodrigues, Claudia V.; Batalha, Celso

    2010-01-15

    A large sample of Herbig Ae/Be (HAeBe) candidates, distributed in different Galactic regions south to declination +30 deg., were identified by the Pico dos Dias Survey (a search for young stellar objects based on IRAS colors). Most of the candidates are nearby or associated with star-forming clouds, but several others are considered isolated objects. Aiming to verify the young nature of 93 HAeBe candidates, we searched for additional information that could be useful to confirm if they are pre-main-sequence (PMS) stars or evolved objects, which coincidentally show similar IRAS colors. By adopting a spectral index that is related to the amount of infrared excess and the shape of the spectral energy distribution, we have classified the sample according to three groups, which are analyzed on the basis of (1) circumstellar luminosity; (2) spatial distribution; (3) optical polarization; (4) near-infrared colors; (5) stellar parameters (mass, age, effective temperature); and (5) intensity of emission lines. Our analysis indicates that only 76% of the studied sample, mainly the group with intermediate to low levels of circumstellar emission, can be more confidently considered PMS stars. The nature of the remaining stars, which are in the other group that contains the highest levels of infrared excess, remains to be confirmed. They share the same characteristics of evolved objects, requiring complementary studies in order to correctly classify them. At least seven objects show characteristics typical of post-asymptotic giant branch or proto-planetary nebulae.

  6. 48 CFR 653.219-70 - DOS form DS-1910, Small Business Agency Review-Actions Above the Simplified Acquisition Threshold.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false DOS form DS-1910, Small... 653.219-70 DOS form DS-1910, Small Business Agency Review—Actions Above the Simplified Acquisition Threshold. As prescribed in 619.501(c), DS-1910 is prescribed for use in documenting set-aside decisions. ...

  7. Cross-Reactive Immunity to Mycobacterium tuberculosis DosR Regulon-Encoded Antigens in Individuals Infected with Environmental, Nontuberculous Mycobacteria▿ †

    PubMed Central

    Lin, May Young; Reddy, T. B. K.; Arend, Sandra M.; Friggen, Annemieke H.; Franken, Kees L. M. C.; van Meijgaarden, Krista E.; Verduyn, Marleen J. C.; Schoolnik, Gary K.; Klein, Michel R.; Ottenhoff, Tom H. M.

    2009-01-01

    Mycobacterium tuberculosis DosR regulon-encoded antigens are highly immunogenic in M. tuberculosis-infected humans and are associated with latent tuberculosis infection. We have investigated the hypothesis that infection with or exposure to nontuberculous mycobacteria (NTM) can induce cross-reactive immunity to M. tuberculosis DosR regulon-encoded antigens since responsiveness has been observed in non-M. tuberculosis-exposed but purified protein derivative-responsive individuals. M. tuberculosis DosR regulon-encoded antigen-specific T-cell responses were studied in peripheral blood mononuclear cells (PBMCs) of NTM-infected/exposed individuals. BLASTP was used to determine the presence of M. tuberculosis DosR regulon-encoded protein orthologs among environmental mycobacteria and nonmycobacteria. Significant gamma interferon production was observed in PBMCs from NTM-infected/exposed individuals in response to M. tuberculosis DosR regulon-encoded antigens. DosR regulon-encoded protein orthologs were prominently present in tuberculous and environmental mycobacteria and surprisingly also in nonmycobacteria. The ubiquitous presence of the highly conserved DosR master regulator protein Rv3133c suggests that this is a general adaptive bacterial response regulator. We report a first series of M. tuberculosis antigens to which cross-reactive immunity is induced by NTM infection/exposure. The high conservation of M. tuberculosis DosR regulon-encoded antigens most likely enables them to induce cross-reactive T-cell responses. PMID:19737909

  8. Lessons Learned from Sleep Education in Schools: A Review of Dos and Don'ts

    PubMed Central

    Blunden, Sarah; Rigney, Gabrielle

    2015-01-01

    Study Objectives: Sleep duration and quality are associated with negative neuropsychological and psychosocial outcomes in children and adolescents. However, community awareness of this is low and sleep education programs in schools are attempting to address this issue. Several studies now exist assessing the efficacy of these sleep education programs for improving sleep knowledge, sleep hygiene and sleep patterns. This paper presents these sleep education programs, most particularly, it presents the strengths and weaknesses of the current available studies in the hope that this can identify areas where future sleep education programs can improve. Methods: A systematic search of all school-based sleep education studies in adolescents was undertaken. Studies were scrutinized for author, teacher and participant comment regarding strengths and limitations of each study, which were then extracted and summarized. Results: Two specific types of sleep education programs emerged from the review, those that sought to change sleep behavior and those that sought simply to disseminate information. Issues that dictated the strength or weakness of a particular study including who delivers the program, the theoretical basis, the tools utilized to measure sleep patterns, the content, and their capacity to engage students were assessed. Sleep education was considered important by teachers, students and parents alike. Conclusions: Future sleep education programs need to take into account lessons learned from previous sleep education efforts in order to maximize the potential for sleep education programs to improve the sleep health of our young people. Commentary: A commentary on this article appears in this issue on page 595. Citation: Blunden S, Rigney G. Lessons learned from sleep education in schools: a review of dos and don'ts. J Clin Sleep Med 2015;11(6):671–680. PMID:25766709

  9. Las dos cosas: an analysis of attitudes of latina women on non-exclusive breastfeeding.

    PubMed

    Bartick, Melissa; Reyes, Catherine

    2012-02-01

    Non-exclusive breastfeeding among Latina women is commonly seen in the newborn period. The reasons behind las dos cosas ("both things") are not well understood but have included the beliefs that formula has vitamins and that adding formula will result in a chubbier baby, which is desirable. Many previous studies involved Mexican and Puerto Rican women living in the mainland United States. We performed detailed semistructured interviews with 17 Latina mothers in late pregnancy or the newborn period at a community hospital and an affiliated clinic in Massachusetts, serving a large Dominican population. Women were asked about their beliefs about breastfeeding, colostrum, and infant formula. Transcripts were analyzed using Nvivo 9 software (QSR International Pty. Ltd., Melbourne, Australia) to identify the frequencies of common trends. The most common reasons for introducing formula were treatment for insufficient milk, to keep the baby fuller longer, and planning for return to work. None of the women understood the potential risks of introducing formula on the establishment of breastfeeding, particularly on milk supply. Many thought that even limited amounts of breastfeeding were sufficient to produce a healthier child, failing to understand a negative dose-response effect of formula on health and milk production. While every woman saw breastfeeding as healthier, only one saw formula as unhealthy, an important distinction. None of the women expressed familiarity with medical recommendations around breastfeeding duration or exclusivity, with many believing that breastmilk alone would be insufficient to satisfy the hunger or nutritional needs of a growing child after as little as 3 months. Women consistently demonstrated a willingness to learn from health professionals. In counseling Latina women, it may be important to discuss the risks of formula to infant health, breastfeeding, and milk supply and to include the medical recommendations for breastfeeding exclusivity

  10. Implementation of DoS attack and mitigation strategies in IEEE 802.11b/g WLAN

    NASA Astrophysics Data System (ADS)

    Deng, Julia; Meng, Ke; Xiao, Yang; Xu, Roger

    2010-04-01

    IEEE 802.11 wireless Local Area Network (WLAN) becomes very prevalent nowadays. Either as a simple range extender for a home wired Ethernet interface, or as a wireless deployment throughout an enterprise, WLAN provides mobility, convenience, and low cost. However, an IEEE 802.11b/g wireless network uses the frequency of unlicensed 2.4GHz, which makes the network unsafe and more vulnerable than traditional Ethernet networks. As a result, anyone who is familiar with wireless network may initiate a Denial of Service (DoS) attack to influence the common communication of the network or even make it crash. In this paper, we present our studies on the DoS attacks and mitigation strategies for IEEE 802.11b/g WLANs and describe some initial implementations using IEEE 802.11b/g wireless devices.

  11. Video movie making using remote procedure calls and 4BSD Unix sockets on Unix, UNICOS, and MS-DOS systems

    SciTech Connect

    Robertson, D.W.; Johnston, W.E.; Hall, D.E.; Rosenblum, M.

    1990-03-01

    We describe the use of the Sun Remote Procedure Call and Unix socket interprocess communication mechanisms to provide the network transport for a distributed, client-server based, image handling system. Clients run under Unix or UNICOS and servers run under Unix or MS-DOS. The use of remote procedure calls across local or wide-area networks to make video movies is addressed.

  12. Diverted organic synthesis (DOS): accessing a new, natural product inspired, neurotrophically active scaffold through an intramolecular Pauson-Khand reaction.

    PubMed

    Mehta, Goverdhan; Samineni, Ramesh; Srihari, Pabbaraja; Reddy, R Gajendra; Chakravarty, Sumana

    2012-09-14

    Drawing inspiration from the impressive neurotrophic activity exhibited by the natural product paecilomycine A, we have designed a new natural product-like scaffold employing an intramolecular Pauson-Khand reaction. Several compounds based on the new designer scaffold exhibited promising neurotrophic activity and are worthy of further biological evaluation. Our findings also highlight the importance of a DOS strategy in creating useful therapeutical leads.

  13. Research on a Denial of Service (DoS) Detection System Based on Global Interdependent Behaviors in a Sensor Network Environment

    PubMed Central

    Song, Jae-gu; Jung, Sungmo; Kim, Jong Hyun; Seo, Dong Il; Kim, Seoksoo

    2010-01-01

    This research suggests a Denial of Service (DoS) detection method based on the collection of interdependent behavior data in a sensor network environment. In order to collect the interdependent behavior data, we use a base station to analyze traffic and behaviors among nodes and introduce methods of detecting changes in the environment with precursor symptoms. The study presents a DoS Detection System based on Global Interdependent Behaviors and shows the result of detecting a sensor carrying out DoS attacks through the test-bed. PMID:22163475

  14. 32 CFR Appendix C to Part 197 - Procedures for the Department of State (DoS) Foreign Relations of the United States (FRUS) Series

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... the DoS for the FRUS series under Public Law No. 102-138. b. Request authorization from the CIA, NSC.... Submit to the respective Agency a list of CIA and NSC documents copied and released to the...

  15. 32 CFR Appendix C to Part 197 - Procedures for the Department of State (DoS) Foreign Relations of the United States (FRUS) Series

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... the DoS for the FRUS series under Public Law No. 102-138. b. Request authorization from the CIA, NSC.... Submit to the respective Agency a list of CIA and NSC documents copied and released to the...

  16. 32 CFR Appendix C to Part 197 - Procedures for the Department of State (DoS) Foreign Relations of the United States (FRUS) Series

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... the DoS for the FRUS series under Public Law No. 102-138. b. Request authorization from the CIA, NSC.... Submit to the respective Agency a list of CIA and NSC documents copied and released to the...

  17. 32 CFR Appendix C to Part 197 - Procedures for the Department of State (DoS) Foreign Relations of the United States (FRUS) Series

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... the DoS for the FRUS series under Public Law No. 102-138. b. Request authorization from the CIA, NSC.... Submit to the respective Agency a list of CIA and NSC documents copied and released to the...

  18. 32 CFR Appendix C to Part 197 - Procedures for the Department of State (DoS) Foreign Relations of the United States (FRUS) Series

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... the DoS for the FRUS series under Public Law No. 102-138. b. Request authorization from the CIA, NSC.... Submit to the respective Agency a list of CIA and NSC documents copied and released to the...

  19. Ada Compiler Validation Summary Report: Certificate Number: 900125N1. 10258, R. R. Software, Inc., Janus/Ada 2.1.3 386 to DOS Bell 386 Under Ms-Dos 4 Host

    DTIC Science & Technology

    1990-01-25

    Ada Validation Vabkdim Swmy Re t AVF-VSR-90502/69 R R Softmm Im 3MW/Ada 21.3 316 to DOS chaplerl - Page I of 5 INTRODUCTION Organization ( AVO ). On...1.2 USE OF THIS VALIDATION SUMMARY REPORT Consistent with the national laws of the originating country, the AVO may make full and free public...contained in the Ada Compiler Validation Procedures and Guidelines. AVO The Ada Validation Organization. The AVO has oversight authority over all AVF

  20. Whole of Government Approach: Maximizing Unity of Effort Between the Department of Defense (DOD), Department of State (DOS), and the United States Agency for International Development (USAID)

    DTIC Science & Technology

    2013-12-13

    WHOLE OF GOVERNMENT APPROACH: MAXIMIZING UNITY OF EFFORT BETWEEN THE DEPARTMENT OF DEFENSE (DOD), DEPARTMENT OF STATE (DOS), AND THE...UNITED STATES AGENCY FOR INTERNATIONAL DEVELOPMENT (USAID) A thesis presented to the Faculty of the U.S. Army Command and General Staff...Government Approach: Maximizing Unity of Effort between the Department of Defense (DoD), Department of State (DoS), and the United States Agency for

  1. The FG loop of a heme-based gas sensor enzyme, Ec DOS, functions in heme binding, autoxidation and catalysis.

    PubMed

    Ito, Shinya; Igarashi, Jotaro; Shimizu, Toru

    2009-10-01

    Ec DOS is a heme-based gas sensor enzyme that catalyzes conversion from cyclic-di-GMP to linear-di-GMP in response to gas molecules, such as oxygen, CO and NO. Ec DOS contains an N-terminal heme-binding PAS domain and C-terminal phosphodiesterase domain. Based on crystal structures of the isolated heme-binding domain, it is suggested that the FG loop is involved in intra-molecular signal transduction to the catalytic domain. We generated nine full-length proteins mutated at ionic and non-ionic polar residues between positions 83 and 96 corresponding to the F-helix and FG loop, and examined the heme binding properties, autoxidation rates, and catalytic activities of mutant proteins. N84A and R85A mutant proteins displayed lower heme binding affinities, consistent with the finding that Asn84 interacts with propionate of protoporphyrin IX, and Arg85 with Asp40 on the heme proximal side. Autoxidation rates (0.058-0.54 min(-1)) of R91A, S96A and K89A/R91A/E93A mutant proteins were significantly higher than that (0.0053 min(-1)) of wild-type protein, suggesting that these residues in the FG loop form heme distal architecture conferring stability to the Fe(II)-O(2) complex. Catalytic activities of N84A and R85A mutant proteins with low heme affinity were significantly higher than those of wild-type protein in the absence of gas molecules. Accordingly, we propose that loss of heme binding enhances basal catalysis without the gas molecule, consistent with previous reports on heme inhibition of Ec DOS catalysis.

  2. Expression, maturation and turnover of DrrS, an unusually stable, DosR regulated small RNA in Mycobacterium tuberculosis

    PubMed Central

    Moores, Alexandra; Riesco, Ana B.; Schwenk, Stefan

    2017-01-01

    Mycobacterium tuberculosis depends on the ability to adjust to stresses encountered in a range of host environments, adjustments that require significant changes in gene expression. Small RNAs (sRNAs) play an important role as post-transcriptional regulators of prokaryotic gene expression, where they are associated with stress responses and, in the case of pathogens, adaptation to the host environment. In spite of this, the understanding of M. tuberculosis RNA biology remains limited. Here we have used a DosR-associated sRNA as an example to investigate multiple aspects of mycobacterial RNA biology that are likely to apply to other M. tuberculosis sRNAs and mRNAs. We have found that accumulation of this particular sRNA is slow but robust as cells enter stationary phase. Using reporter gene assays, we find that the sRNA core promoter is activated by DosR, and we have renamed the sRNA DrrS for DosR Regulated sRNA. Moreover, we show that DrrS is transcribed as a longer precursor, DrrS+, which is rapidly processed to the mature and highly stable DrrS. We characterise, for the first time in mycobacteria, an RNA structural determinant involved in this extraordinary stability and we show how the addition of a few nucleotides can lead to acute destabilisation. Finally, we show how this RNA element can enhance expression of a heterologous gene. Thus, the element, as well as its destabilising derivatives may be employed to post-transcriptionally regulate gene expression in mycobacteria in combination with different promoter variants. Moreover, our findings will facilitate further investigations into the severely understudied topic of mycobacterial RNA biology and into the role that regulatory RNA plays in M. tuberculosis pathogenesis. PMID:28323872

  3. Expression, maturation and turnover of DrrS, an unusually stable, DosR regulated small RNA in Mycobacterium tuberculosis.

    PubMed

    Moores, Alexandra; Riesco, Ana B; Schwenk, Stefan; Arnvig, Kristine B

    2017-01-01

    Mycobacterium tuberculosis depends on the ability to adjust to stresses encountered in a range of host environments, adjustments that require significant changes in gene expression. Small RNAs (sRNAs) play an important role as post-transcriptional regulators of prokaryotic gene expression, where they are associated with stress responses and, in the case of pathogens, adaptation to the host environment. In spite of this, the understanding of M. tuberculosis RNA biology remains limited. Here we have used a DosR-associated sRNA as an example to investigate multiple aspects of mycobacterial RNA biology that are likely to apply to other M. tuberculosis sRNAs and mRNAs. We have found that accumulation of this particular sRNA is slow but robust as cells enter stationary phase. Using reporter gene assays, we find that the sRNA core promoter is activated by DosR, and we have renamed the sRNA DrrS for DosR Regulated sRNA. Moreover, we show that DrrS is transcribed as a longer precursor, DrrS+, which is rapidly processed to the mature and highly stable DrrS. We characterise, for the first time in mycobacteria, an RNA structural determinant involved in this extraordinary stability and we show how the addition of a few nucleotides can lead to acute destabilisation. Finally, we show how this RNA element can enhance expression of a heterologous gene. Thus, the element, as well as its destabilising derivatives may be employed to post-transcriptionally regulate gene expression in mycobacteria in combination with different promoter variants. Moreover, our findings will facilitate further investigations into the severely understudied topic of mycobacterial RNA biology and into the role that regulatory RNA plays in M. tuberculosis pathogenesis.

  4. Clinical reasoning in nursing: teaching strategies and assessment tools.

    PubMed

    Carvalho, Emília Campos de; Oliveira-Kumakura, Ana Railka de Souza; Morais, Sheila Coelho Ramalho Vasconcelos

    2017-01-01

    To present the concept and development of teaching strategies and the assessment tools regarding clinical reasoning for accurate practice. This is a theoretical reflection based on scientific studies. Comprehension of the essential concepts of the thought process and its articulation with the different teaching strategies and the assessment tools which has allowed presenting ways to improve the process of diagnostic or therapeutic clinical reasoning. The use of new strategies and assessment tools should be encouraged in order to contribute to the development of skills that lead to safe and effective decision making. Apresentar o conceito de raciocínio clínico, seu desenvolvimento, as estratégias para seu ensino e os instrumentos de avaliação para uma prática acurada. Trata-se de uma reflexão teórica fundamentada em estudos científicos. A compreensão dos conceitos essenciais do processo de pensamento e sua articulação com as diferentes estratégias de ensino e com os instrumentos de avaliação permitiram exemplificar meios de aprimorar o processo de raciocínio clínico diagnóstico ou terapêutico. A utilização de novas estratégias e instrumentos de avaliação deve ser estimulado para contribuir com o desenvolvimento das habilidades que culminam na tomada de decisão segura e eficaz.

  5. Rare earth elements in Angra dos Reis and Lewis Cliff 86010, two meteorites with similar but distinct magma evolutions

    NASA Technical Reports Server (NTRS)

    Crozaz, Ghislaine; Mckay, Gordon

    1990-01-01

    Data are presented on ion microprobe measurements of REE and selected trace element abundances in individual grains of merrillite, fassaite, olivine, kirschsteinite, and plagioclase of Lewis Cliff 86010 (LEW 86010) meteorite and in merrillite and fassaite grains of Angra dos Reis (ADOR). Results show a close relationship between the two meteorites and support a magmatic origin for LEW 86010. However, the measurements indicate that, despite numerous common characteristics, the two meteorites must have been produced in separate magmatic events involving similar but distinct processes and parent melts.

  6. The influence of climate change on wine production - the case of the Touriga Nacional grape variety (Quinta dos Termos, Portugal)

    NASA Astrophysics Data System (ADS)

    Fonseca, João

    2017-04-01

    The regional and local climate, heavily influenced by global climate change, has strong implications for agriculture. Wine production which has specific characteristics in terms of climate and soil is undoubtedly one of the economic activities strongly influenced by climate change. Quinta dos Termos located in Beira Interior (Belmonte, Portugal) is the largest wine producer in the DOC Beira Interior region, producing premium to hiper premium wines of excellence, marketed at both national and international levels, and cultivates the vineyards according to the rules of Integrated Crop Management. Moreover, grapes are free from herbicides, pesticides or any other chemicals that can be harmful to the environment and health. These factors have contributed to the socio-economic development of the region, creating wealth, favoring employment and promoting tourism. The quality of the wines produced by Quinta dos Termos result from its terroir, given its granite region, the sun exposure, the wind protection, the atmospheric humidity and temperature, the soil water content, the mineralogical/organic composition and soil porosity. These factors favor unique conditions for the cultivation of Touriga Nacional grape variety, which is recognized by its extremely complex color and aroma, which allows the production of wines with great balance and a good ageing potential. Touriga Nacional, a red grape variety of Portuguese origin with high qualitative excellence and reputation and much appreciated worldwide, is versatile to several types of soils and resistant to high thermal amplitudes. Nevertheless, the climatic changes that has been gradually verified, the type of crop management, and in particular the reputation of Touriga Nacional grape variety, may be compromised in the long term, given that these characteristics are strongly influenced by the climate and soil. Aware of that, Quinta dos Termos has been performing a monitoring of the vineyards in terms of pedological treatment

  7. Perfil de temperatura dos funis magnetosféricos de estrelas T Tauri com aquecimento alfvênico

    NASA Astrophysics Data System (ADS)

    Vasconcelos, M. J.

    2003-08-01

    Estrelas T Tauri Clássicas são objetos jovens circundados por discos de gás e poeira e que apresentam uma intensa atividade magnética. Seu espectro mostra linhas de emissão alargadas que são razoavelmente reproduzidas nos modelos de acresção magnetosférica. No entanto, o perfil de temperatura dos funis magnéticos é desconhecido. Aquecimento magnético compressional e difusão ambipolar foram considerados para estas estruturas, porém as temperaturas obtidas não são suficientes para explicar as observações. Neste trabalho, examinamos o aquecimento gerado pelo amortecimento de ondas Alfvén através de quatro mecanismos, os amortecimentos não-linear, turbulento, viscoso-resistivo e colisional como função da freqüência da onda. Inicialmente, a temperatura é ajustada para reproduzir as observações e o grau de turbulência requerido para que o mecanismo seja viável é calculado. Os resultados mostram que este é compatível com os dados observacionais. Apresentam-se, também, resultados preliminares do cálculo auto-consistente do perfil de temperatura dos funis, levando-se em conta fontes de aquecimento Alfvênica e fontes de resfriamento.

  8. Species richness of fern and lycophyte in an urban park in the Rio dos Sinos basin, Southern Brazil.

    PubMed

    Schmitt, J L; Goetz, M N B

    2010-12-01

    In the northeastern region of the State of Rio Grande do Sul in Southern Brazil, specifically in the Rio dos Sinos basin, urban parks are an important alternative for the conservation of the remaining natural habitats, as well as for the maintenance and perpetuation of biodiversity. A floristic survey of fern and lycophyte species in the Parque Municipal Henrique Luís Roessler (PMHLR) (29º 41' S and 51º 06' W; alt. 16.4 m) in Novo Hamburgo, (State of Rio Grande do Sul, RS) described their life-forms, as well as substrates and preferential environments. Forty-three species, 30 genera and 15 families were found, 39 of which were ferns. The hemicryptophytes had the highest species richness (26), 17 of which were repent, and nine, rosulate. Most species were found in terrestrial substrates (32) and inside the forest (29). Species richness in the PMHLR corresponded to about 13% of the total fern and lycophyte species listed for the State of Rio Grande do Sul, which demonstrates the importance of conservation areas in the Rio dos Sinos basin as an alternative to the preservation of local biodiversity.

  9. Didelphidae marsupials (Mammalia, Didelphimorphia) from the late Pleistocene deposit of the Gruta dos Moura Cave, northern Brazil.

    PubMed

    Nova, Patricia Villa; Avilla, Leonardo S; Oliveira, Édison V

    2015-03-01

    The present study acknowledges the diversity of fossil marsupials from the Gruta dos Moura cave, as well as environmental and climatic aspects during the Quaternary. The results show that this is the largest diversity of Pleistocene marsupials recorded in a single cave: Didelphis albiventris, D. aurita, Gracilinanus agilis, G. microtarsus, Marmosa murina, Monodelphis brevicaudata, M. domestica and Sairadelphys tocantinensis. Furthermore, the described specimens are also part of the only fossil assemblage unequivocally referable to the late Pleistocene. Paleontological studies suggest an intimate association with dry and open environments with high abundance of water sources. Since most of the identified taxa are characteristic of open forests and gallery forests, this could represent the actual environment around the Gruta dos Moura cave. Recent studies identified sympatric occurrences between species from open and dry environments and species from humid forests that were identified among our material and are characteristic of humid regions. Therefore, these species could inhabit gallery forests and capons, or even ecotones, inside a dry and open environment. Moreover, the extinction of Sairadelphys could also indicate that the climatic and environmental conditions changed or that the past environment was more heterogeneous than the current environment of the region.

  10. Cmr is a redox-responsive regulator of DosR that contributes to M. tuberculosis virulence

    PubMed Central

    Bochkareva, Aleksandra; Rolfe, Matthew D.; Hunt, Debbie M.; Kahramanoglou, Christina; Braun, Yvonne; Rodgers, Angela; Blockley, Alix; Coade, Stephen; Lougheed, Kathryn E.A.; Hafneh, Nor Azian; Glenn, Sarah M.; Crack, Jason C.; Le Brun, Nick E.; Saldanha, José W.; Makarov, Vadim; Nobeli, Irene; Mukamolova, Galina V.; Buxton, Roger S.; Green, Jeffrey

    2017-01-01

    Abstract Mycobacterium tuberculosis (MTb) is the causative agent of pulmonary tuberculosis (TB). MTb colonizes the human lung, often entering a non-replicating state before progressing to life-threatening active infections. Transcriptional reprogramming is essential for TB pathogenesis. In vitro, Cmr (a member of the CRP/FNR super-family of transcription regulators) bound at a single DNA site to act as a dual regulator of cmr transcription and an activator of the divergent rv1676 gene. Transcriptional profiling and DNA-binding assays suggested that Cmr directly represses dosR expression. The DosR regulon is thought to be involved in establishing latent tuberculosis infections in response to hypoxia and nitric oxide. Accordingly, DNA-binding by Cmr was severely impaired by nitrosation. A cmr mutant was better able to survive a nitrosative stress challenge but was attenuated in a mouse aerosol infection model. The complemented mutant exhibited a ∼2-fold increase in cmr expression, which led to increased sensitivity to nitrosative stress. This, and the inability to restore wild-type behaviour in the infection model, suggests that precise regulation of the cmr locus, which is associated with Region of Difference 150 in hypervirulent Beijing strains of Mtb, is important for TB pathogenesis. PMID:28482027

  11. Supporting Security against SYN Flooding Attack in Distributed DoS Via Measuring IPFIX-Based Traffic

    NASA Astrophysics Data System (ADS)

    Alipour, H.; Kia, M. Kashefi; Esmaeili, M.

    Distributed denial-of-service attacks on public servers after 2000 have become a serious problem. In the distributed denial-of-service (DDoS) attacks often seen recently, multiple distributed nodes concurrently attack a single server. To assure that network services will not be interrupted, faster and more effective defense mechanisms is needed to protect against malicious traffic, especially SYN floods. One problem in detecting SYN flood traffic is that server nodes or firewalls cannot distinguish the SYN packets of normal TCP connections from those of a SYN flood attack. Our method, FDFIX, relies on the use of monitoring and measurement techniques to evaluate the impact of DoS attacks. It uses flow based measurements. Capturing flow information is very important for detecting DoS and also other kinds of attacks. Flow monitoring allows detecting suspicious traffics and in the next step can analyze attacking flows and the results can be used for defense methods. Our method provides required information for many mechanisms that use traffic measurement as their input.

  12. Degradability of dimethyl terephthalate by Variovorax paradoxus T4 and Sphingomonas yanoikuyae DOS01 isolated from deep-ocean sediments.

    PubMed

    Wang, Yu Ping; Gu, Ji-Dong

    2006-08-01

    Two strains of bacteria were isolated from deep-ocean sediments of the South China Sea using enrichment culturing technique and they were identified as Sphingomonas yanoikuyae DOS01 (AY878409) and Variovorax paradoxus T4 (AY878410) based on 16S rRNA gene sequences. S. yanoikuyae DOS01 was only capable of transforming dimethyl terephthalate (DMTP) to monomethyl terephthalate (MMTP) without further degradation while V. paradoxus T4 exhibited ability in mineralizing DMTP as the sole source of carbon and energy. The biochemical pathway of DMTP degradation was through MMTP and terephthalic acid (TA) as major detectable degradation intermediates in the culture media by both microorganisms. V. paradoxus T4 utilized DMTP and MMTP via hydrolysis of diester and monoester in the initial steps in degradation as confirmed by total organic carbon analysis of the culture medium and esterase activity assay of the lysed cells and fraction. The specific hydrolysis activity of esterase induced by DMTP or MMTP showed that greater hydrolysis of p-nitrophenyl acetate by esterase induced by DMTP-grown cells than that induced by MMTP. Results of this research suggest that the cleavage of the two identical carboxylic ester groups of phthalate diester are carried out by highly specific esterases of the same bacteria in the environment.

  13. Contextual variation in young children's observed disruptive behavior on the DB-DOS: implications for early identification.

    PubMed

    Petitclerc, Amélie; Briggs-Gowan, Margaret J; Estabrook, Ryne; Burns, James L; Anderson, Erica L; McCarthy, Kimberly J; Wakschlag, Lauren S

    2015-09-01

    Contextual variation in child disruptive behavior is well documented but remains poorly understood. We first examine how variation in observed disruptive behavior across interactional contexts is associated with maternal reports of contextual variation in oppositional-defiant behavior and functional impairment. Second, we test whether child inhibitory control explains the magnitude of contextual variation in observed disruptive behavior. Participants are 497 young children (mean age = 4 years, 11 months) from a subsample of the MAPS, a sociodemographically diverse pediatric sample, enriched for risk of disruptive behavior. Observed anger modulation and behavioral regulation problems were coded on the Disruptive Behavior Diagnostic Observation Schedule (DB-DOS) during interactions with parent and examiner. Oppositional-defiant behavior, and impairment in relationships, with parents and nonparental adults, were measured with the Preschool Age Psychiatric Assessment (PAPA) interview with the mother. Functional impairment in the home and out-and-about was assessed with the Family Life Impairment Scale (FLIS), and expulsion from child care/school was measured with the baseline survey and FLIS. Observed disruptive behavior on the DB-DOS Parent Context was associated with oppositional-defiant behavior with parents, and with impairment at home and out-and-about. Observed disruptive behavior with the Examiner was associated with oppositional-defiant behavior with both parents and nonparental adults, impairment in relationships with nonparental adults, and child care/school expulsion. Differences in observed disruptive behavior in the Parent versus Examiner Contexts was related to the differences in maternal reports of oppositional-defiant behavior with parents versus nonparental adults. Children with larger decreases in disruptive behavior from Parent to Examiner Context had better inhibitory control and fewer attention-deficit/hyperactivity disorder symptoms. The DB-DOS

  14. Contextual variation in young children’s observed disruptive behavior on the DB-DOS: implications for early identification

    PubMed Central

    Petitclerc, Amélie; Briggs-Gowan, Margaret J.; Estabrook, Ryne; Burns, James L.; Anderson, Erica L.; McCarthy, Kimberly J.; Wakschlag, Lauren S.

    2015-01-01

    Background Contextual variation in child disruptive behavior is well documented but remains poorly understood. We first examine how variation in observed disruptive behavior across interactional contexts is associated with maternal reports of contextual variation in oppositional-defiant behavior and functional impairment. Second, we test whether child inhibitory control explains the magnitude of contextual variation in observed disruptive behavior. Methods Participants are 497 young children (mean age = 4 years, 11 months) from a subsample of the MAPS, a sociodemographically diverse pediatric sample, enriched for risk of disruptive behavior. Observed anger modulation and behavioral regulation problems were coded on the Disruptive Behavior Diagnostic Observation Schedule (DB-DOS) during interactions with parent and examiner. Oppositional-defiant behavior, and impairment in relationships, with parents and nonparental adults, were measured with the Preschool Age Psychiatric Assessment (PAPA) interview with the mother. Functional impairment in the home and out-and-about was assessed with the Family Life Impairment Scale (FLIS), and expulsion from child care/school was measured with the baseline survey and FLIS. Results Observed disruptive behavior on the DB-DOS Parent Context was associated with oppositional-defiant behavior with parents, and with impairment at home and out-and-about. Observed disruptive behavior with the Examiner was associated with oppositional-defiant behavior with both parents and nonparental adults, impairment in relationships with nonparental adults, and child care/school expulsion. Differences in observed disruptive behavior in the Parent versus Examiner Contexts was related to the differences in maternal reports of oppositional-defiant behavior with parents versus nonparental adults. Children with larger decreases in disruptive behavior from Parent to Examiner Context had better inhibitory control and fewer attention

  15. [The Arabic influence in the "Colóquios dos simples e drogas da India" of Garcia da Orta].

    PubMed

    Ricordel, Joëlle

    2015-09-01

    The "Colóquios dos simples e drogas he cousas medicinais de Índia" (Conversations on the simples, drugs and medicinal substances of India) (1563) of Garcia da Orta is a botanical and pharmacognosy book. The author is a Portuguese physician who studied in the Spanish universities and practiced medicine mainly in India. He studies in short chapters presented in the form of dialogues about sixty simples. Sources to which he refers are indicative of a "classical" training, but also the mark of a curious and open mind to different cultures. The Arabic sources are numerous and mainly concern the identification of substances by abundant synonyms of their names in foreign languages and different medicinal uses that may have been done by the ancient physicians. However, Da Orta is critical with respect to these sources, seeking contradictions and differences of opinion among authors. He confronts them with the oral information collected thanks to a wide network of contacts.

  16. NGC 2287: Un cúmulo abierto rico en binarias espectroscópicas de dos espectros

    NASA Astrophysics Data System (ADS)

    Levato, H.; Malaroda, S.; García, B.; Grosso, M.

    NGC 2287 contiene 100 estrellas con buena fotometría y 40 con tipos MK. En 1979 Levato et al., usando la técnica de la clasificación espectral, descubrieron que la mayoría de las estrellas en el rango B8-A0 eran binarias espectroscópicas con una inusual proporción de binarias con dos espectros. El presente proyecto tuvo el propósito de confirmar la naturaleza binaria de los miembros del cúmulo. Hemos obtenido espectros con resolución 14000 de 15 estrellas clasificadas como binarias. Los espectros, que abarcan la región λ 3500-λ 6000 Å, permitieron confirmar la naturaleza binaria de varias de las estrellas en la muestra. Hacemos notar el considerable interés astrofísico de este cúmulo abierto.

  17. Another new and threatened species of lancehead genus Bothrops (Serpentes, Viperidae) from Ilha dos Franceses, Southeastern Brazil.

    PubMed

    Barbo, Fausto E; Gasparini, João Luiz; Almeida, Antonio P; Zaher, Hussam; Grazziotin, Felipe G; Gusmão, Rodrigo B; Ferrarini, José Mário G; Sawaya, Ricardo J

    2016-04-04

    A new insular species of the genus Bothrops is described from Ilha dos Franceses, a small island off the coast of Espírito Santo State, in southeastern Brazil. The new species differs from mainland populations of B. jararaca mainly by its small size, relative longer tail, relative smaller head length, and relative larger eyes. The new species is distinguished from B. alcatraz, B. insularis and B. otavioi by the higher number of ventral and subcaudal scales, relative longer tail and smaller head. The new species is highly abundant on the island, being nocturnal, semiarboreal, and feeding on small lizards and centipeds. Due its unique and restricted area of occurrence, declining quality of habitat, and constant use of the island for tourism, the new species may be considered as critically endangered.

  18. Application of geostatistical methods to arsenic data from soil samples of the Cova dos Mouros mine (Vila Verde-Portugal).

    PubMed

    Reis, A P; Sousa, A J; Da Silva, E Ferreira; Fonseca, E Cardoso

    2005-09-01

    A total of 286 soil samples were collected in the Cova dos Mouros area. All samples were dry sieved into the <200 mesh size fraction and analysed for Fe, Cu, Zn, Pb, Co, Ni, Bi and Mn by atomic absorption spectrometry (AAS) and for As, Se, Sb and Te by atomic absorption spectrometry-hydrid generation (AAS-HG). Only the results of arsenic are discussed in this paper although the survey was extended to all analysed chemical elements. The purpose of this study was to make a risk probability mapping for arsenic that would allow better knowledge about the vulnerability of the soil to arsenic contamination. To achieve this purpose, the initial variable was transformed into an indicator variable using as thresholds the risk-based standards (intervention values) for soils, as proposed by [Swartjes 1999. Risk based assessment of soil and groundwater quality in the Netherlands: Standards and remediation. J. Geochem. Explor.73 1-10]. To account for spatial structure, sample variograms were computed for the main directions of the sampling grid and a spherical model was fitted to each sample variogram (arsenic variable and indicator variables). The parameters of the spherical model fitted to the arsenic variable were used to predict arsenic concentrations at unsampled locations. A risk probability mapping was also done to assess the vulnerability of the soil towards the mining works. The parameters of the spherical model fitted to each indicator variable were used to estimate probabilities of exceeding the corresponding threshold. The use of indicator kriging as an alternative to ordinary kriging for the soil data of Cova dos Mouros produced unbiased probability maps that allowed assessment of the quality of the soil.

  19. Observações no âmbito dos "additional programs" do satélite COROT

    NASA Astrophysics Data System (ADS)

    Janot Pacheco, E.

    2003-08-01

    O satélite Fraco-europeu COROT fará fotometria de altissima precisão (pretende-se atingir uma parte em um milhão), grande campo (3x3 graus) e por longos períodos, de duas regiões pré-determinadas do céu, com 10 graus de raio. Suas finalidades básicas serão estudos em sismologia estelar e a procura de exoplanetas. A comunidade astronômica brasileira participará dessa missão espacial, com direitos iguais aos dos parceiros europeus. Isso se deve a que o satélite utilizará a estação de recepção de dados de Natal (INPE), 5 a 6 brasileiros participarão das equipes de software e cientistas do país atuarão na fase de pré-lançamento. Apresentamos nesta comunicação sugestões para a preparação de propostas de observações com COROT, no âmbito dos Programas Adicionais, que contemplam outros projetos que não de sismologia ou exoplanetas. As últimas definições técnicas e decisões tomadas na 4th Corot Week de junho último serão igualmente apresentadas, em particular quanto às regiões de observação escolhidas e quanto aos procedimentos a seguir para se propor observações.

  20. Long term exposure to organochlorine pesticides and thyroid function in children from Cidade dos Meninos, Rio de Janeiro, Brazil.

    PubMed

    Freire, Carmen; Koifman, Rosalina Jorge; Sarcinelli, Paula; Rosa, Ana Cristina; Clapauch, Ruth; Koifman, Sergio

    2012-08-01

    A pesticide factory in Cidade dos Meninos village, Duque de Caxias County, Rio de Janeiro, Brazil, ended its activity in 1961, leading to widespread contamination of the environment by several organochlorine pesticides. The aim of this study was to investigate the effects of chronic exposure to organochlorine pesticides on thyroid hormone levels in children residing in Cidade dos Meninos. In a population-based survey carried out between 2003 and 2004, serum concentration of 19 pesticides and levels of free thyroxine (T4), total triiodothyronine (T3) and thyroid-stimulating hormone (TSH) were determined in 193 children younger than 15 years old. Multivariate linear regression was conducted to examine thyroid hormone levels according to quintiles of organochlorine exposure, controlling for age, gender and serum lipid content. Free T4 and TSH levels were within reference values (0.7-1.8 ng/dl and 0.35-5.5 mU/l), whereas total T3 was above the reference range (80-180 ng/dl) in 28% of children. More than 60% of the children had detectable levels of most organochlorine pesticides. With the exception of heptachlor and methoxychlor, total T3 levels showed a significant increasing linear trend regardless of pesticide type to which children were exposed. Free T4 levels were positively and significantly associated only with exposure to p,p'-DDD, endosulfan 1, and dieldrin. No significant trend was found for TSH. Data showed that exposure of children to organochlorine pesticides produced a significant increase in serum total T3 concentrations. The clinical implications of such a total T3 elevation and subsequent development are uncertain and warrant the need for health monitoring of these children.

  1. Evolution of the Astronomy Concepts Along Basic Education Cycle. (Breton Title: Evolução dos Conceitos de Astronomia no Decorrer da Educação Básica.) La Evolución de los Conceptos de Astronomía Durante la Educación Básica

    NASA Astrophysics Data System (ADS)

    Darroz, Luiz Marcelo; da Rosa, Cleci Werner; Becker da Rosa, Álvaro; Samudio Pèrez, Carlos Ariel

    2014-07-01

    learning of astronomy in basic education. Embora a astronomia seja considerada uma das ciências mais antigas da humanidade e ainda que a compreensão de seus conceitos tenha trazido enormes avanços para a Ciência e, consequentemente, para a sociedade, observa-se que uma parcela significativa de pessoas encontra-se à margem desses conhecimentos. De acordo com os Parâmetros Curriculares Nacionais para a Educação Básica, cabe à escola a difusão dos conceitos cientificamente corretos, entre eles os relacionados à área de astronomia. Pertinente a essa questão, apresenta-se uma pesquisa realizada com 140 estudantes do nono ano do ensino fundamental e com 120 estudantes da terceira série do ensino médio de quatro escolas da região de Passo Fundo/RS. Buscou-se averiguar, por meio de um questionário composto de questões abertas e de múltipla escolha, o conhecimento desse grupo de estudantes acerca de termos e fenômenos astronômicos básicos e, também, verificar se o índice de acertos cresce à medida que eles avançam nas diferentes e gradativas séries dos ensinos fundamental e médio. De modo geral, os resultados apresentados demonstram que o ensino de astronomia na educação básica enfrenta deficiências. Das 20 questões investigadas, em 17 os índices de acertos são semelhantes nas respostas dadas por estudantes de nível fundamental e médio, revelando que muitas concepções equivocadas permanecem ao longo da educação básica. Isso evidencia que tais temas não são - ou são pouco - abordados durante esses dois níveis de escolarização. Assim, conclui-se que a discussão dos conceitos relacionados com a astronomia deve receber maior ênfase na abordagem dos diferentes conteúdos, sendo necessária uma ação nacional em prol do seu ensino. Acredita-se que essa ação nacional deve estar apoiada em um pilar triplo de atores coletivos: comunidade científica, comunidade astronômica semiprofissional e comunidade escolar. Por fim, esse pilar seria

  2. Dynamics of the T cell response to Mycobacterium tuberculosis DosR and Rpf antigens in a Colombian population of household contacts of recently diagnosed pulmonary tuberculosis patients.

    PubMed

    Arroyo, Leonar; Rojas, Mauricio; Ortíz, Blanca L; Franken, Kees L M C; García, Luis F; Ottenhoff, Tom H M; Barrera, Luis F

    2016-03-01

    Immune response to DosR and Rpf antigens from Mycobacterium tuberculosis (Mtb) seems to be important for latency maintenance. Little is known about the dynamics of the immune response to these antigens in an endemic community. Thus, the IFNγ response and cytokine production in response to PPD, Esat6-Cfp10 (E6-C10), DosR and Rpf antigens in healthy HHC of tuberculosis (TB) patients over a 12 (T12) months period (short-term, stLTBI) was investigated. This response was compared with a group of LTBI, who have remained healthy for 5-7 years (long-term, ltLTBI). According to the IFNγ response, two groups of HHCs were identified in stLTBI in response to E6-C10. At T12, E6-C10(+) HHCs displayed a decrease in the IFNγ levels and a generalized decrease in cytokines production. The E6-C10(-) HHC showed an increase in the IFNγ response and cytokine levels. In stLTBI, the responses to E6-C10, DosR, and Rpf may be interpreted as a protective immune response controlling Mtb infection and may be leading to a state of latent infection. Comparing the response of stLTBI and ltLTBI, we observed significant changes in the proportions of CD45RO(+)CD27(+) T cells to specific DosR and Rpf, which may indicate a persistent immune response to Mtb antigens in ltLTBI.

  3. Mycobacterium tuberculosis DosR is Required for Activity of the PmbtB and PmbtI Promoters under Hypoxia

    PubMed Central

    Schreuder, Lise J.; Parish, Tanya

    2014-01-01

    Mycobacterium tuberculosis has the ability to survive for extended periods of time under conditions of low oxygen, low pH, low iron and low nutrients. The mycobactins (M. tuberculosis siderophores) play a key role in scavenging iron from the environment and are induced in response to low iron in an IdeR-regulated manner. We demonstrate that the promoters of two mycobactin gene (mbt) operons are also expressed during adaptation to low oxygen, and that this expression is dependent on the DosR regulator. Up-regulation of mbt operons induced by low iron was not DosR-dependent. DosR is a member of a two component regulatory system which responds to oxygen availability. Deletion of the DosR regulator led to increased expression of bacterioferritin and increased capacity to grow under iron depletion. These data provide a link between the mycobacterial response to two conditions likely to be encountered in vivo, low iron and low oxygen. PMID:25211224

  4. 48 CFR 653.219-71 - DOS form DS-4053, Department of State Mentor-Protégé Program Application.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ..., Department of State Mentor-Protégé Program Application. 653.219-71 Section 653.219-71 Federal Acquisition Regulations System DEPARTMENT OF STATE CLAUSES AND FORMS FORMS Prescription of Forms 653.219-71 DOS form DS-4053, Department of State Mentor-Protégé Program Application. As prescribed in 619.102-70(i),...

  5. 48 CFR 653.219-71 - DOS form DS-4053, Department of State Mentor-Protégé Program Application.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ..., Department of State Mentor-Protégé Program Application. 653.219-71 Section 653.219-71 Federal Acquisition Regulations System DEPARTMENT OF STATE CLAUSES AND FORMS FORMS Prescription of Forms 653.219-71 DOS form DS-4053, Department of State Mentor-Protégé Program Application. As prescribed in 619.102-70(i),...

  6. 48 CFR 653.219-71 - DOS form DS-4053, Department of State Mentor-Protégé Program Application.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ..., Department of State Mentor-Protégé Program Application. 653.219-71 Section 653.219-71 Federal Acquisition Regulations System DEPARTMENT OF STATE CLAUSES AND FORMS FORMS Prescription of Forms 653.219-71 DOS form DS-4053, Department of State Mentor-Protégé Program Application. As prescribed in 619.102-70(i),...

  7. 48 CFR 653.219-71 - DOS form DS-4053, Department of State Mentor-Protégé Program Application.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ..., Department of State Mentor-Protégé Program Application. 653.219-71 Section 653.219-71 Federal Acquisition Regulations System DEPARTMENT OF STATE CLAUSES AND FORMS FORMS Prescription of Forms 653.219-71 DOS form DS-4053, Department of State Mentor-Protégé Program Application. As prescribed in 619.102-70(i),...

  8. 48 CFR 653.219-71 - DOS form DS-4053, Department of State Mentor-Protégé Program Application.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ..., Department of State Mentor-Protégé Program Application. 653.219-71 Section 653.219-71 Federal Acquisition Regulations System DEPARTMENT OF STATE CLAUSES AND FORMS FORMS Prescription of Forms 653.219-71 DOS form DS-4053, Department of State Mentor-Protégé Program Application. As prescribed in 619.102-70(i),...

  9. Immunogenicity of Novel DosR Regulon-Encoded Candidate Antigens of Mycobacterium tuberculosis in Three High-Burden Populations in Africa▿ †

    PubMed Central

    Black, Gillian F.; Thiel, Bonnie A.; Ota, Martin O.; Parida, Shreemanta K.; Adegbola, Richard; Boom, W. Henry; Dockrell, Hazel M.; Franken, Kees L. M. C.; Friggen, Annemiek H.; Hill, Philip C.; Klein, Michel R.; Lalor, Maeve K.; Mayanja, Harriet; Schoolnik, Gary; Stanley, Kim; Weldingh, Karin; Kaufmann, Stefan H. E.; Walzl, Gerhard; Ottenhoff, Tom H. M.

    2009-01-01

    Increasing knowledge about DosR regulon-encoded proteins has led us to produce novel Mycobacterium tuberculosis antigens for immunogenicity testing in human populations in three countries in Africa to which tuberculosis (TB) is endemic. A total of 131 tuberculin skin test-positive and/or ESAT-6/CFP10-positive, human immunodeficiency virus-negative adult household contacts of active pulmonary TB cases from South Africa (n = 56), The Gambia (n = 26), and Uganda (n = 49) were tested for gamma interferon responses to 7 classical and 51 DosR regulon-encoded M. tuberculosis recombinant protein antigens. ESAT-6/CFP10 fusion protein evoked responses in >75% of study participants in all three countries. Of the DosR regulon-encoded antigens tested, Rv1733c was the most commonly recognized by participants from both South Africa and Uganda and the third most commonly recognized antigen in The Gambia. The four most frequently recognized DosR regulon-encoded antigens in Uganda (Rv1733c, Rv0081, Rv1735c, and Rv1737c) included the three most immunogenic antigens in South Africa. In contrast, Rv3131 induced the highest percentage of responders in Gambian contacts (38%), compared to only 3.4% of Ugandan contacts and no South African contacts. Appreciable percentages of TB contacts with a high likelihood of latent M. tuberculosis infection responded to several novel DosR regulon-encoded M. tuberculosis proteins. In addition to significant similarities in antigen recognition profiles between the three African population groups, there were also disparities, which may stem from genetic differences between both pathogen and host populations. Our findings have implications for the selection of potential TB vaccine candidates and for determining biosignatures of latent M. tuberculosis infection, active TB disease, and protective immunity. PMID:19553548

  10. MprA and DosR coregulate a Mycobacterium tuberculosis virulence operon encoding Rv1813c and Rv1812c.

    PubMed

    Bretl, Daniel J; He, Hongjun; Demetriadou, Crystalla; White, Mark J; Penoske, Renee M; Salzman, Nita H; Zahrt, Thomas C

    2012-09-01

    Mycobacterium tuberculosis remains a significant global pathogen, causing extensive morbidity and mortality worldwide. This bacterium persists within granulomatous lesions in a poorly characterized, nonreplicating state. The two-component signal transduction systems MprAB and DosRS-DosT (DevRS-Rv2027c) are responsive to conditions likely to be present within granulomatous lesions and mediate aspects of M. tuberculosis persistence in vitro and in vivo. Here, we describe a previously uncharacterized locus, Rv1813c-Rv1812c, that is coregulated by both MprA and DosR. We demonstrate that MprA and DosR bind to adjacent and overlapping sequences within the promoter region of Rv1813c and direct transcription from an initiation site located several hundred base pairs upstream of the Rv1813 translation start site. We further show that Rv1813c and Rv1812c are cotranscribed, and that the genomic organization of this operon is specific to M. tuberculosis and Mycobacterium bovis. Although Rv1813c is not required for survival of M. tuberculosis in vitro, including under conditions in which MprAB and DosRST signaling are activated, an M. tuberculosis ΔRv1813c mutant is attenuated in the low-dose aerosol model of murine tuberculosis, where it exhibits a lower bacterial burden, delayed time to death, and decreased ability to stimulate proinflammatory cytokines interleukin-1β (IL-1β) and IL-12. Interestingly, overcomplementation of these phenotypes is observed in the M. tuberculosis ΔRv1813c mutant expressing both Rv1813c and Rv1812c, but not Rv1813c alone, in trans. Therefore, Rv1813c and Rv1812c may represent general stress-responsive elements that are necessary for aspects of M. tuberculosis virulence and the host immune response to infection.

  11. MprA and DosR Coregulate a Mycobacterium tuberculosis Virulence Operon Encoding Rv1813c and Rv1812c

    PubMed Central

    Bretl, Daniel J.; He, Hongjun; Demetriadou, Crystalla; White, Mark J.; Penoske, Renee M.; Salzman, Nita H.

    2012-01-01

    Mycobacterium tuberculosis remains a significant global pathogen, causing extensive morbidity and mortality worldwide. This bacterium persists within granulomatous lesions in a poorly characterized, nonreplicating state. The two-component signal transduction systems MprAB and DosRS-DosT (DevRS-Rv2027c) are responsive to conditions likely to be present within granulomatous lesions and mediate aspects of M. tuberculosis persistence in vitro and in vivo. Here, we describe a previously uncharacterized locus, Rv1813c-Rv1812c, that is coregulated by both MprA and DosR. We demonstrate that MprA and DosR bind to adjacent and overlapping sequences within the promoter region of Rv1813c and direct transcription from an initiation site located several hundred base pairs upstream of the Rv1813 translation start site. We further show that Rv1813c and Rv1812c are cotranscribed, and that the genomic organization of this operon is specific to M. tuberculosis and Mycobacterium bovis. Although Rv1813c is not required for survival of M. tuberculosis in vitro, including under conditions in which MprAB and DosRST signaling are activated, an M. tuberculosis ΔRv1813c mutant is attenuated in the low-dose aerosol model of murine tuberculosis, where it exhibits a lower bacterial burden, delayed time to death, and decreased ability to stimulate proinflammatory cytokines interleukin-1β (IL-1β) and IL-12. Interestingly, overcomplementation of these phenotypes is observed in the M. tuberculosis ΔRv1813c mutant expressing both Rv1813c and Rv1812c, but not Rv1813c alone, in trans. Therefore, Rv1813c and Rv1812c may represent general stress-responsive elements that are necessary for aspects of M. tuberculosis virulence and the host immune response to infection. PMID:22689819

  12. Activation of ATP binding for the autophosphorylation of DosS, a Mycobacterium tuberculosis histidine kinase lacking an ATP lid motif.

    PubMed

    Cho, Ha Yeon; Lee, Young-Hoon; Bae, Young-Seuk; Kim, Eungbin; Kang, Beom Sik

    2013-05-03

    The sensor histidine kinases of Mycobacterium tuberculosis, DosS and DosT, are responsible for sensing hypoxic conditions and consist of sensor and kinase cores responsible for accepting signals and phosphorylation activity, respectively. The kinase core contains a dimerization and histidine phosphate-accepting (DHp) domain and an ATP binding domain (ABD). The 13 histidine kinase genes of M. tuberculosis can be grouped based on the presence or absence of the ATP lid motif and F box (elements known to play roles in ATP binding) in their ABDs; DosS and DosT have ABDs lacking both these elements, and the crystal structures of their ABDs indicated that they were unsuitable for ATP binding, as a short loop covers the putative ATP binding site. Although the ABD alone cannot bind ATP, the kinase core is functional in autophosphorylation. Appropriate spatial arrangement of the ABD and DHp domain within the kinase core is required for both autophosphorylation and ATP binding. An ionic interaction between Arg(440) in the DHp domain and Glu(537) in the short loop of the ABD is available and may open the ATP binding site, by repositioning the short loop away from the site. Mutations at Arg(440) and Glu(537) reduce autophosphorylation activity. Unlike other histidine kinases containing an ATP lid, which protects bound ATP, DosS is unable to accept ATP until the ABD is properly positioned relative to the histidine; this may prevent unexpected ATP reactions. ATP binding can, therefore, function as a control mechanism for histidine kinase activity.

  13. [Manifestatations of violence in adolescents in public schools in the municipality of Jaboatão dos Guararapes].

    PubMed

    Melo, Monica Cristina Batista de; Barros, Erika Neves de; Almeida, Andréa Maria Lages Gomes de

    2011-10-01

    Adolescence is a period in human development characterized by profound biological, psychological and social modifications affecting both adolescents and their entire social and family environment. This stage, which has good character forming opportunities, is also permeated by various risks, including violence. Nowadays, violence is the main cause of death among adolescents and is considered a public health concern. This research sought to investigate manifestations of violence in adolescents from public schools of the municipality of Jaboatão dos Guararapes. This is a qualitative study, in which the data obtained from a questionnaire was analyzed using the content analysis technique. The results show that the main manifestations of violence involve harm to others. Drug usage was revealed as the main motive behind physical violence. The deployment of more policemen was the strategy most cited and strengthening the family unit was the most commented preventative measure. In conclusion, the importance of further discussion about disguised manifestations of violence is clear as this would contribute to reflections on new prevention proposals and greater visibility of the phenomenon.

  14. Impacts of the globalized economy on the environment: the tanning industry in the Vale do Rio dos Sinos.

    PubMed

    Figueiredo-Sganderla, J A; Prodanov, C C; Daroit, D

    2010-12-01

    This case study analysed the impact of the global economy on the environment of the Vale do Rio do Sinos region in southern Brazil. Interviews and questionnaires were used to collect data from social, cultural, economic and political agents in this region, and documents about the tanning industry were reviewed and analysed. Global perspectives and local conditions were brought together to understand the causes and consequences of social, political and economic structures and to evaluate the intrinsic association of the tanning industry with the social, historical and cultural development of the Vale do Rio dos Sinos. The behaviour of the local community, where individuals believe that progress is primordially based on industrial development and go to any lengths to achieve it, was also studied. The analysis of industries that have a high contamination potential revealed that dirty industries moved from central to peripheral countries up to the 1980s, but movement is currently internal and occurs between states in Brazil due to several types of incentives.

  15. Groundwater radon, radium and uranium concentrations in Região dos Lagos, Rio de Janeiro State, Brazil.

    PubMed

    Almeida, R M R; Lauria, D C; Ferreira, A C; Sracek, O

    2004-01-01

    Ground water from Região dos Lagos, a coastal area of Rio de Janeiro state, was analysed for (226)Ra, (228)Ra, (222)Rn, (238)U, major ion concentrations, and physico-chemical parameters were also measured. Concentrations values ranged from <0.002 to 0.492 Bq l(-1) for (226)Ra, from <0.01 to 1.50 Bq l(-1) for (228)Ra and from < 1.0 x 10(-4) to 8.0 x 10(-2) Bq l(-1) for (238)U. Detectable (222)Rn concentrations (>3 Bq l(-1)) were found only in two samples. The spatial distribution of Ra concentration delineated one distinct area and some hot spots with high Ra concentration. Low pH value is the most important water parameter linked to high radium concentration. This is probably related to limited adsorption of radium on soil ferric oxides and hydroxides at low pH range. There was a significant correlation between uranium concentrations and electrical conductivity values, and also between uranium concentrations and concentrations of Ca, Mg, Na, K, and Cl, indicating sea water impact. Uranium concentrations were lower than maximum contaminant level for drinking water, whereas 17 out of the 88 ground water samples had levels of radium that exceeded the maximum contaminant level for tap water. The total annual effective dose for adult due to the water consumption reaches values up to 0.8 mSv.

  16. ESR dating of Smilodon populator from Toca de Cima dos Pilão, Piauí, Brazil.

    PubMed

    Kinoshita, Angela; Mollemberg, Michelle; Santana, William; G Figueiredo, Ana Maria; Guidon, Niede; Fátima da Luz, Maria de; Guérin, Claude; Baffa, Oswaldo

    2017-02-01

    Smilodon is a genus of big cats that lived from the early to the late Pleistocene in regions extending from North to South America. The fossil records of the "saber-toothed cats" are uneven, with some taxa being quite abundant in certain regions. In Brazil, Smilodon populator is a well-known species whose remains, although scarce in comparison to other large mammals, are found all across the country. In particular, there are multiple records of this species in the region of the Serra da Capivara National Park. This area was home to a rich Pleistocene-Holocene fauna, including many mammals. Here, we report on the Electron Spin Resonance dating of a Smilodon populator tooth found in "Toca de Cima dos Pilão", located in the surroundings of the Serra da Capivara National Park. The equivalent dose found after exponential fitting of dose-response curve was (2.7±0.3)x10(2)Gy. Neutron Activation Analysis was used to determine the concentration of radioisotopes present in the sample and in the sediment to calculate the internal and external dose rates. The result of age found is 93±9ka, which confirmed the presence of this species in Serra da Capivara National Park in the late Pleistocene.

  17. Brief communication: "Zuzu" strikes again--morphological affinities of the early holocene human skeleton from Toca dos Coqueiros, Piaui, Brazil.

    PubMed

    Hubbe, Mark; Neves, Walter A; do Amaral, Heleno Licurgo; Guidon, Niéde

    2007-10-01

    The Serra da Capivara National Park in northeastern Brazil is one of the richest archaeological regions in South America. Nonetheless, so far only two paleoindian skeletons have been exhumed from the local rockshelters. The oldest one (9870 +/- 50 BP; CAL 11060 +/- 50), uncovered in Toca dos Coqueiros and known as "Zuzu," represents a rare opportunity to explore the biological relationships of paleoindian groups living in northeastern Brazil. As previously demonstrated, South and Central America Paleoindians present skull morphology distinct from the one found nowadays in Amerindians and similar to Australo-Melanesians. Here we test the hypothesis that Zuzu shows higher morphological affinity with Paleoindians. However, Zuzu is a controversial skeleton since previous osteological assessments have disagreed on several aspects, especially regarding its sex. Thus, we compared Zuzu to males and females independently. Morphological affinities were assessed through clustering of principal components considering 18 worldwide populations and through principal components analysis of the individual dispersion of five key regions for America's settlement. The results obtained do not allow us to refute the hypothesis, expanding the known geographical dispersion of the Paleoindian morphology into northeast Brazil. To contribute to the discussion regarding Zuzu's sex, a new estimation is presented based on visual inspection of cranial and post-cranial markers, complemented by a discriminant analysis of its morphology in relation to the paleoindian sample. The results favor a male classification and are consistent with the mortuary offerings found in the burial, yet do not agree with a molecular determination.

  18. Power-efficiency trade-off due to density of states (DOS) distortion in a molecular thermoelectric system

    NASA Astrophysics Data System (ADS)

    Desouza, Priyanka; Muralidharan, Bhaskaran

    2013-03-01

    The issue of how a distortion in the electronic DOS affects nanoscale thermoelectric performance is addressed within an ``electrical engineering'' perspective. This view point is based on the direct evaluation of the overall efficiency and power from device current-voltage characteristics and gives a more complete picture of the thermoelectric performance in comparison to the traditional ``figure of merit'' based material science approach. We use representative examples from molecular conduction to study the trade-off between maximum efficiency and the maximum power generated within the set up. The trade-off is maximum for the well known example of a sharply resonant molecular level which represents the ultimate distortion in the electronic density of states. As the distortion is reduced via contact induced broadening, we obtain a smaller trade-off between maximum power and efficiency. We then present the effects of self consistent charging, contact induced asymmetry and the HOMO-LUMO gap on the thermoelectric performance. In all cases we compare our non-equilibrium calculations with zT calculations, and our results depict that zT is not the sole metric for the assessment of nanoscale thermoelectric performance.

  19. Holocene history of a lake filling and vegetation dynamics of the Serra Sul dos Carajás, southeast Amazonia.

    PubMed

    Guimarães, José T F; Sahoo, Prafulla K; Souza-Filho, Pedro W M; Figueiredo, Mariana M J Costa DE; Reis, Luiza S; Silva, Marcio S DA; Rodrigues, Tarcísio M

    2017-07-24

    Down-core changes in sedimentary facies, elemental geochemistry, pollen, spore, δ13C, δ15N and radiocarbon records from a filled lake, named R4, of the Serra Sul dos Carajás were used to study the relationship between the paleomorphological and paleoecological processes and their significance for Holocene paleoclimatology of the southeast Amazonia. The sediment deposition of the R4 lake started around 9500 cal yr BP. Increase of detrital components from 9500 to 7000 cal yr BP suggests high weathering of surrounding catchment rocks and soils, and deposition into the lake basin under mudflows. At that time, montane savanna and forest formation were already established suggesting predominance of wet climate. However, from 7000 to 3000 cal yr BP, a decline of detrital input occurred. Also, forest formation and pteridophytes were declined, while palms and macrophytes were remained relatively stable, indicating that water levels of the lake is likely dropped allowing the development of plants adapted to subaerial condition under drier climate conditions. After 3000 cal yr BP, eutrophication and low accommodation space lead to high lake productivity and the final stage of the lake filling respectively, and forest formation may has acquired its current structure, which suggests return of wetter climate conditions.

  20. Dos Amigos... (Two Friends...).

    ERIC Educational Resources Information Center

    Aguilar, Rosalie M.

    Intended for supplementary reading material for Spanish speaking children in elementary grades, this illustrated Spanish text was developed by students in the Bilingual Teacher Aide Program at Mesa Community College. Both language and content have been controlled to provide linguistically and culturally sensitive material relevant to the…

  1. [Hypertension in women: study in mothers of students from Jaboatão dos Guararapes, Pernambuco, Brazil].

    PubMed

    Teodósio, Marta Regueira; Freitas, Clara Lúcia C de; Santos, Naíde Teodósio Valois; Oliveira, Eliane da Cunha Mendonça de

    2004-01-01

    The purpose of this research was to study the prevalence of hypertension in apparently healthy women community with a view preparing a program for primary prevention of hypertension. The population survey involved a representative sample of mothers of 126.800 students enrolled at schools of Jaboatão dos Guararapes, Pernambuco, Brasil. The population size (1.273 students) was selected from a 5% +/- 2% expected frequency of the hypertension in children with a confidence level of 99.9%. This study comprised 21 schools and a random sample of 986 mothers of 1.601 students). Two blood pressure measurements separated by 2 minutes were carried out in the schools on two subsequent visits. The corporal mass index was determined in 893 mothers. In a group of 671 mothers, a midstream urine specimen was collected and the dip - stick was used to assess the presence of urinary abnormalities. The prevalence of the hypertension was 27.7% and it was significantly higher (p<0.01) in overweight (28.5%) and obese women (57%) than normal weight women (14%) and underweight women (12%). There was significant difference regarding the presence of glucosuria between the hypertensives and the normotensives women (3% and 0%, respectively). In a group of 62 hypertensives women with followup at 3 to 12 month interval, the blood pressure has been controlled in 13 (21%) and remains below the initial hypertensive stage in 27 (43.5%). The prevalence of hypertension (27,7%) do agree with the data in the literature concerning hypertension in women (26%), showing a higher tendency in overweight and obese women. We are continuing the followup of the hypertensive women as well as developing a community program for primary prevention of hypertension in the target population.

  2. En la búsqueda de características en eyecciones coronales de masa que discriminen entre dos paradigmas físicos en modelos de ECMs

    NASA Astrophysics Data System (ADS)

    Paissan, G.; Stenborg, G.; Rovira, M.

    Se conocen tres diferentes fenómenos de gran escala que ocurren en la atmósfera solar, denominados eyecciones coronales de masa (ECMs), protuberancias eruptivas y grandes fulguraciones de dos bandas. Estos fenómenos están estrechamente relacionados y podrían ser distintas manifestaciones de un único proceso físico. Las ECMs son definidas como eyecciones de gran escala de masa y flujo magnético desde la baja corona al espacio interplanetario. Desde su descubrimiento en los '70, muchos modelos han sido propuestos para explicar su origen y evolución. La explicación física de las ECMs es un tema de debate intenso. No obstante, los modelos pueden sintetizarse en dos grandes grupos: 1) los modelos de inyección de flujo y 2) los modelos de almacenamiento y liberación. En este trabajo, se presentan los estudios realizados con una serie de eventos observados con el coronógrafo MICA (Mirror Coronograph for Argentina), el telescopio en H-alfa HASTA (H-alpha Solar Telescope for Argentina) y los coronógrafos C2 y C3 de la sonda SOHO (Solar and Heliospheric Observatory). Los eventos que pudieron ser identificados como ECMs son contrastados dentro del esquema de los dos paradigmas teóricos propuestos.

  3. The petrochemistry of the auriferous, volcanosedimentary Riacho dos Machados Group, Central-eastern Brazil: geotectonic implications for shear-hosted gold mineralization

    NASA Astrophysics Data System (ADS)

    da Fonseca, E.; Lobato, L. M.; Baars, F. J.

    1997-12-01

    The Ouro Fino Gold Deposit at the Riacho dos Machados Mine is located in the Araçuaí Fold Belt at the eastern margin of the São Francisco Craton. The gold is shear zone-hosted and associated principally with a sulphide-bearing, quartzmuscovite schist, derived from the hydrothermal alteration of pelitic and quartzofeldspathic schists of the Riacho dos Machados Group (RMG). Along the shear zones, mineral associations typical of the amphibolite facies are progressively altered to assemblages typical of the greenschist facies. It has become evident from the studies that the process of segregation and concentration of chemical elements and minerals is the very process of mineralization, involving the concentration of Au. The RMG comprises ultramafic, mafic and acid metavolcanic rocks intercalated in a sequence of metapelites. The metapelites have textures and geochemistry compatible with greywackes. The dacitic and mafic/ultramafic rocks are of calc-alkaline and tholeiitic subalkaline association, respectively. The RMG probably formed within a continental volcanic arc. The thrust faults that establish the regional architecture, and which host the Riacho dos Machados gold mineralization, are related to a continental collision of unknown age between the precursor to the São Francisco Craton and the Guanambi-Correntina Block.

  4. Queda dos homicídios em São Paulo, Brasil: uma análise descritiva

    PubMed Central

    Peres, Maria Fernanda Tourinho; Vicentin, Diego; Nery, Marcelo Batista; de Lima, Renato Sérgio; de Souza, Edinilsa Ramos; Cerda, Magdalena; Cardia, Nancy; Adorno, e Sérgio

    2012-01-01

    Objetivo Descrever a evolução da mortalidade por homicídios no Município de São Paulo segundo tipo de arma, sexo, raça ou cor, idade e áreas de exclusão/inclusão social entre 1996 e 2008. Métodos Estudo ecológico de série temporal. Os dados sobre óbitos ocorridos no Município foram coletados da base de dados do Programa de Aprimoramento das Informações sobre Mortalidade, seguindo a Classificação Internacional de Doenças, Décima Revisão (CID-10). Foram calculadas as taxas de mortalidade por homicídio (TMH) para a população total, por sexo, raça ou cor, faixa etária, tipo de arma e área de exclusão/inclusão social. As TMH foram padronizadas por idade pelo método direto. Foram calculados os percentuais de variação no período estudado. Para as áreas de exclusão/inclusão social foram calculados os riscos relativos de morte por homicídio. Resultados As TMH apresentaram queda de 73,7% entre 2001 e 2008. Foi observada redução da TMH em todos os grupos analisados, mais pronunciada em homens (−74,5%), jovens de 15 a 24 anos (−78,0%) e moradores de áreas de exclusão social extrema (−79,3%). A redução ocorreu, sobretudo, nos homicídios cometidos com armas de fogo (−74,1%). O risco relativo de morte por homicídio nas áreas de exclusão extrema (tendo como referência áreas com algum grau de exclusão social) foi de 2,77 em 1996, 3,9 em 2001 e 2,13 em 2008. Nas áreas de alta exclusão social, o risco relativo foi de 2,07 em 1996 e 1,96 em 2008. Conclusões Para compreender a redução dos homicídios no Município, é importante considerar macrodeterminantes que atingem todo o Município e todos os subgrupos populacionais e microdeterminantes que atuam localmente, influenciando de forma diferenciada os homicídios com armas de fogo e os homicídios na população jovem, no sexo masculino e em residentes em áreas de alta exclusão social. PMID:21390415

  5. 2.3 Å X-ray Structure of the Heme-Bound GAF Domain of Sensory Histidine Kinase DosT of Mycobacterium tuberculosis†

    PubMed Central

    Podust, Larissa M.; Ioanoviciu, Alexandra; Ortiz de Montellano, Paul R.

    2009-01-01

    Mycobacterium tuberculosis responds to the changes in environmental conditions through a two-component signaling system that detects reduced O2 tension and NO and CO exposures via the heme-binding GAF domains of two sensory histidine kinases, DosT and DevS, and the transcriptional regulator DosR. We report the first x-ray structure of the DosT heme-bound GAF domain (GAFDosT) in both oxy and deoxy forms determined to a resolution of 2.3 Å. In GAFDosT, heme binds in an orientation orthogonal to that in the PAS domains via a highly conserved motif including invariant H147 as a proximal heme axial ligand. On the distal side, invariant Y169 is in stacking interactions with the heme with its long axis parallel and the plane of the ring orthogonal to the heme plane. In one of the two protein monomers in an asymmetric unit, O2 binds as a second axial ligand to the heme iron, and is stabilized via an H-bond to the OH-group of Y169. The structure reveals two small tunnel-connected cavities and a pore on the protein surface that suggest a potential route for O2 access to the sensing pocket. The limited conformational differences observed between differently heme iron-ligated GAFDosT monomers in the asymmetric unit may result from crystal lattice limitations since atmospheric oxygen binding likely occurs in the crystal as a result of x-ray induced Fe3+ photoreduction during diffraction data collection. Determination of the GAFDosT structure sets up a framework in which to address ligand-recognition, discrimination, and signal propagation schemes in the heme-based GAF domains of biological sensors. PMID:18980385

  6. [Species from genus Eimeria observed in domestic rabbit (Oryctolagus cuniculus) feces raised at the Municipality of Campos dos Goytacazes in the State of Rio de Janeiro, Brazil].

    PubMed

    de Almeida, Adriana J; Mayen, Friederike L; de Oliveira, Francisco C R

    2006-01-01

    This study was designed to identify species of the genus Eimeria from eleven rabbit meat breeders from Campos dos Goytacazes. Fecal samples were collected from rabbits with different health conditions and consintence of feces. The following species of Eimeria were identified: E. perforans; E. magna; E. coecicola; E. irresidua; E. media; E. flavescens; E. nagpurensis; E. intestinalis, E. exigua and E. stiedae. Parasites from this genus were detected in 81.82% (9) of the rabbit meat production sites, regardless of the management and hygiene conditions. In all cases the infection was always caused from more than one species of Eimeria.

  7. Hepatitis A seroprevalence in public school children in Campos dos Goytacazes, Rio de Janeiro State, Brazil, prior to the introduction of the hepatitis A universal childhood vaccination.

    PubMed

    Kury, Charbell Miguel; Pinto, Marcelo Alves; Silva, Jaquelline Pereira da; Cruz, Oswaldo Gonçalves; Vitral, Claudia Lamarca

    2016-11-01

    This cross-sectional study was carried out between August 2011 and July 2012 in the city of Campos dos Goytacazes in Rio de Janeiro State, Brazil. Dried blood spot samples were collected on filter paper from 919 individuals between the ages of 1 and 19 and were tested for antibodies against the hepatitis A virus (anti-HAV). The total prevalence was 20.7%, while 94.7% of children under the age of 5 were found to be susceptible to HAV infection. The prevalence of anti-HAV increased with age, reaching 33.3% among individuals aged between 15 and 19, thereby indicating that this municipality has a low level of endemicity for hepatitis A. Age, non-white skin color, accustomed to swimming in the river and more than five people living at home were the factors that were associated with an increase in the chance of a positive anti-HAV result. Mother's education level (secondary or tertiary) was considered a protective factor for HAV infection. The data obtained showed that a large proportion of the children from Campos dos Goytacazes were at risk of HAV infection, which should be minimized with the introduction of the vaccination program against hepatitis A that was launched in the municipality in 2011.

  8. Católicos, fidelidade conjugal e AIDS: entre a cruz da doutrina moral e as espadas do cotidiano sexual dos adeptos1

    PubMed Central

    Rios, Luis Felipe; de Aquino, Francisca Luciana; Muñoz-Laboy, Miguel; Oliveira, Cinthia; Parker, Richard

    2009-01-01

    Neste artigo discutimos a visão da Igreja Católica sobre sexualidade na interface com a epidemia do HIV/AIDS. Nossa reflexão está embasada em pesquisa etnográfica que envolveu dois meses de observação participante do cotidiano de católicos de um bairro popular da Região Metropolitana do Recife, além de contar com entrevistas a onze dos leigos engajados nos serviços religiosos da igreja do bairro e a oito sacerdotes que realizam seus trabalhos religiosos em outras localidades. Nelas abordamos diferentes temáticas relacionadas ao enfrentamento da epidemia da AIDS. Nesse contexto, conjugalidade e fidelidade se afiguram como importantes analisadores de como aqueles lidam com a epidemia, em uma variedade de re-descrições práticas e de re-interpretações conceptuais das assertivas do discurso moral religioso – ainda que, muitos impasses permaneçam em aberto em termos das prerrogativas da Igreja e seus possíveis rebatimentos na saúde sexual dos adeptos. PMID:21765650

  9. Detection of IgG1 antibodies against Mycobacterium tuberculosis DosR and Rpf antigens in tuberculosis patients before and after chemotherapy.

    PubMed

    Mattos, Ana Márcia Menezes; Chaves, Alexandre Silva; Franken, Kees L M C; Figueiredo, Bárbara Bruna Muniz; Ferreira, Ana Paula; Ottenhoff, Tom H M; Teixeira, Henrique Couto

    2016-01-01

    Diagnosis of tuberculosis (TB) remains challenging. Serum IgG1 antibodies against Mycobacterium tuberculosis active growth phase antigens (ESAT-6/CFP-10, Rv0717 and Rv3353), DosR regulon-encoded proteins (Rv1733, Rv1737, Rv2628 and Rv2029), and resuscitation-promoting factors (Rv0867 and Rv2389) were evaluated in TB patients using ELISA. Active TB patients showed elevated levels of IgG1 antibodies against ESAT-6/CFP-10, Rv0717, Rv3353, Rv1733, Rv2628, Rv2029 and Rv0867 in comparison to healthy controls (p < 0.001). These levels remained high after the initiation of treatment, while responses to Rv0717 and Rv1733 peaked early during treatment. IgG1 responses to ESAT-6/CFP-10, Rv3353, Rv2628, Rv2029 and Rv0867 declined to control levels after the completion of 6 months chemotherapy. ROC analysis confirmed the good diagnostic performance of Rv0717, Rv1733, Rv3353, Rv2628, Rv2029 and Rv0867antigens. These data suggest that detecting IgG1 antibodies against M. tuberculosis antigens, including DosR and Rpf proteins, may represent an additional tool in the diagnosis of tuberculosis.

  10. A Influência da Escola e da Mídia na Obtenção dos Conhecimentos Astronômicos

    NASA Astrophysics Data System (ADS)

    da Cunha, W. S.; Voelzke, M. R.; Amaral, L. H.

    2006-08-01

    O universo em que vivemos possui segredos jamais imaginados pelo homem, fruto da pequena proporção que ocupamos diante de um cosmos infinito. A astronomia funciona como um instrumento que sacia a sede humana em desvendar esses segredos, estudando as galáxias, quasares, pulsares além da existência de todos os elementos que preenchem o espaço cósmico, o vácuo, não mais vazio como se pensou em outros tempos. A mídia explora esse campo de forma mística e também científica. A difusão adequada e dentro dos padrões educacionais vigentes, de conceitos astronômicos, se faz necessária, devido sua presença nos conteúdos escolares, centros de ciência e na mídia, de modo geral. A reforma do Currículo Básico da Escola Pública da maioria dos Estados brasileiros introduziu conceitos astronômicos desde a pré-escola até o Ensino Médio. Num estudo realizado com 1.032 alunos do Ensino Médio de seis escolas estaduais, revelou-se através da aplicação de um questionário que abordava conheciment os básicos em astronomia, como estes foram adquiridos e qual era a infra-estrutura oferecida pela escola: para 66,2% dos entrevistados o professor já fez alguma apresentação a respeito de astronomia. O presente estudo revelou também que 44,5% dos alunos entrevistados adquiriram seus conhecimentos astronômicos na escola, 28,1% através da televisão e 27,4% afirmaram que seus conhecimentos foram obtidos através de outros tipos de mídia (internet, filmes e revistas). Embora o estudo revele claramente que há certo equilíbrio na forma em que os alunos obtiveram seus conhecimentos astronômicos, a mídia ainda explora e muitas vezes desperta o interesse pela astronomia com assuntos que não fazem parte de nosso cotidiano como, por exemplo, o homem na Lua, os projetos espaciais e a primeira viagem de um astronauta brasileiro no espaço. Porém, em certos casos, a mídia pode promover conhecimentos incompletos ou mesmo equivocados sobre os conceitos que envolvam

  11. Establishing the Empirical Relationship Between Non-Science Majoring Undergraduate Learners' Spatial Thinking Skills and Their Conceptual Astronomy Knowledge. (Spanish Title: Estableciendo Una Relación Empírica Entre el Razonamiento Espacial de los Estudiantes de Graduación de Carreras no Científicas y su Conocimento Conceptual de la Astronomía.) Estabelecendo Uma Relação Empírica Entre o RacioCínio Espacial dos Estudantes de Graduação EM Carreiras Não Científicas e Seu Conhecimento Conceitual da Astronomia

    NASA Astrophysics Data System (ADS)

    Heyer, Inge; Slater, Stephanie J.; Slater, Timothy F.

    2013-12-01

    normalizadas, en el desempeño de los estudiantes en estos dos asuntos foram pequenas, 0.26 e 0.13 respectivamente. El razonamiento espacial de los estudiantes fue medido utilizando un instrumento específico desarrollado para este trabaljo. Las correlaciones entre los resultados de los tests astronómicos y este instrumento específico, antes y después del curso mostraron una relación entre moderada y fuerte, sugiriendo que la relación entre el razonamiento espacial y el conocimiento astronómico puede explicar hasta un 25% de la variación em el desempeño de los estudiantes. A comunidade da educação em astronomia tem suposto de forma implícita que o aprendizado da astronomia consiste em um domínio conceitual fundamentado no raciocínio espacial. Como um primeiro passo para identificar formalmente uma relação empírica entre estas duas coisas, utilizamos como amostra os estudantes de graduação de carreiras não científicas de um curso exploratório em uma universidade norte-americana do meio-oeste de médio porte com programa de Doutorado em andamento, onde estes estudantes foram submetidos a um diagnóstico de raciocino espacial e conceitos astronômicos antes e depois do mesmo. As ferramentas utilizadas foram o Test Of Astronomy Standards (TOAST) e o questionário What do you know? Utilizando somente dados completamente consistentes para esta análise, nossa amostra consistiu de 86 estudantes de graduação. As melhoras, depois de normalizadas, do desempenho dos estudantes nos dois quesitos foram pequenas, 0.26 e 0.13 respectivamente. O raciocínio espacial dos estudantes foi medido utilizando um instrumento específico desenhado para este trabalho. As correlações entre os resultados dos testes astronômicos e este instrumento específico antes e depois do curso mostraram uma relação entre moderada e forte, sugerindo que a relação entre o raciocínio espacial e o conhecimento astronômico pode explicar até um 25% na variação no desempenho dos

  12. Multifunctional T Cell Response to DosR and Rpf Antigens Is Associated with Protection in Long-Term Mycobacterium tuberculosis-Infected Individuals in Colombia

    PubMed Central

    Arroyo, Leonar; Rojas, Mauricio; Franken, Kees L. M. C.; Ottenhoff, Tom H. M.

    2016-01-01

    Multifunctional T cells have been shown to be protective in chronic viral infections. In mycobacterial infections, however, evidence for a protective role of multifunctional T cells remains inconclusive. Short-term cultures of peripheral blood mononuclear cells stimulated with the Mycobacterium tuberculosis RD1 antigens 6-kDa early secretory antigenic target (ESAT6) and 10-kDa culture filtrate antigen (CFP10), which are induced in the early infection phase, have been mainly used to assess T cell multifunctionality, although long-term culture assays have been proposed to be more sensitive than short-term assays for assessment of memory T cells, which are essential for long-term immunity. Here we used a long-term culture assay system to study the T cell immune responses to the M. tuberculosis latency-associated DosR antigens and reactivation-associated Rpf antigens, compared to ESAT6 and CFP10, in patients with pulmonary tuberculosis (PTB) and household contacts of PTB patients with long-term latent tuberculosis infection (ltLTBI), in a community in which M. tuberculosis is endemic. Our results showed that the DosR antigens Rv1737c (narK2) and Rv2029c (pfkB) and the Rv2389c (rpfD) antigen of M. tuberculosis induced higher frequencies of CD4+ or CD8+ mono- or bifunctional (but not multifunctional) T cells producing interferon gamma (IFN-γ) and/or tumor necrosis alpha (TNF-α) in ltLTBI, compared to PTB. Moreover, the frequencies of CD4+ and/or CD8+ T cells with a CD45RO+ CD27+ phenotype were higher in ltLTBI than in PTB. Thus, the immune responses to selected DosR and Rpf antigens may be associated with long-term latency, correlating with protection from M. tuberculosis reactivation in ltLTBI. Further study of the functional and memory phenotypes may contribute to further discrimination between the different states of M. tuberculosis infections. PMID:27489136

  13. Geochemical and isotopic evidence for the petrogenesis and emplacement tectonics of the Serra dos Órgãos batholith in the Ribeira belt, Rio de Janeiro, Brazil

    NASA Astrophysics Data System (ADS)

    Machado, Rômulo; Philipp, Ruy Paulo; McReath, Ian; Peucat, Jean Jacques

    2016-07-01

    The Serra dos Órgãos batholith in the State of Rio de Janeiro (Brazil) is a NE-SW-trending elongated body that occupies ca. 5000 km2 in plan view. It is a foliated intrusion, especially at its borders and is crosscut by syn-magmatic shear zones, with foliations that are moderately-to steeply-dipping to the northwest and moderately-to shallow-dipping in the center and to the southeast, in a configuration of a large laccolith. It was emplaced between 560 and 570 Ma, during an extensional episode that was part of a series of events that comprise the Brasiliano Orogeny in SE Brazil, and which includes deformation, metamorphism and granite intrusion during the interval between 630 and 480 Ma. The two main rock types in the batholith are biotite-hornblende monzogranite, and biotite leucogranite, with subordinate tonalite, granodiorite, diorite, quartz diorite (enclaves), aplite and pegmatite. Harker-type diagrams help show two rock groups with similar trends of evolution: a dioritic and a granitic. The first one is tholeiitic, whereas the second is calc-alkaline, with medium-to high-K calc-alkaline affinity and metaluminous to slightly peraluminous character. In both groups strong decrease in Al2O3, MgO, FeOT and CaO relative to silica contents are observed, which is compatible with trends of fractional crystallization involving clinopyroxene and/or hornblende, plagioclase, opaque minerals, apatite, microcline and biotite. The Sr and Nd isotopic data suggest recycling of a Paleoproterozoic crust as an important petrological process to generate the batholith rocks. Geothermometry (amphibole composition) and geobarometry (saturation in zircon and apatite) indicate that most of the batholith solidified at mid to lower crustal levels at about 750 °C and between 5 and 5.5 kbar. We consider that Serra dos Órgãos crustal protoliths underwent melting caused by the interaction with hotter mafic magma at the base of the crust. These two magmas, with distinct initial

  14. Multifunctional T Cell Response to DosR and Rpf Antigens Is Associated with Protection in Long-Term Mycobacterium tuberculosis-Infected Individuals in Colombia.

    PubMed

    Arroyo, Leonar; Rojas, Mauricio; Franken, Kees L M C; Ottenhoff, Tom H M; Barrera, Luis F

    2016-10-01

    Multifunctional T cells have been shown to be protective in chronic viral infections. In mycobacterial infections, however, evidence for a protective role of multifunctional T cells remains inconclusive. Short-term cultures of peripheral blood mononuclear cells stimulated with the Mycobacterium tuberculosis RD1 antigens 6-kDa early secretory antigenic target (ESAT6) and 10-kDa culture filtrate antigen (CFP10), which are induced in the early infection phase, have been mainly used to assess T cell multifunctionality, although long-term culture assays have been proposed to be more sensitive than short-term assays for assessment of memory T cells, which are essential for long-term immunity. Here we used a long-term culture assay system to study the T cell immune responses to the M. tuberculosis latency-associated DosR antigens and reactivation-associated Rpf antigens, compared to ESAT6 and CFP10, in patients with pulmonary tuberculosis (PTB) and household contacts of PTB patients with long-term latent tuberculosis infection (ltLTBI), in a community in which M. tuberculosis is endemic. Our results showed that the DosR antigens Rv1737c (narK2) and Rv2029c (pfkB) and the Rv2389c (rpfD) antigen of M. tuberculosis induced higher frequencies of CD4(+) or CD8(+) mono- or bifunctional (but not multifunctional) T cells producing interferon gamma (IFN-γ) and/or tumor necrosis alpha (TNF-α) in ltLTBI, compared to PTB. Moreover, the frequencies of CD4(+) and/or CD8(+) T cells with a CD45RO(+) CD27(+) phenotype were higher in ltLTBI than in PTB. Thus, the immune responses to selected DosR and Rpf antigens may be associated with long-term latency, correlating with protection from M. tuberculosis reactivation in ltLTBI. Further study of the functional and memory phenotypes may contribute to further discrimination between the different states of M. tuberculosis infections.

  15. Geology and geochemistry of Pelagatos, Cerro del Agua, and Dos Cerros monogenetic volcanoes in the Sierra Chichinautzin Volcanic Field, south of México City

    NASA Astrophysics Data System (ADS)

    Agustín-Flores, Javier; Siebe, Claus; Guilbaud, Marie-Noëlle

    2011-04-01

    This study focuses on the geology and geochemistry of three closely-spaced monogenetic volcanoes that are located in the NE sector of the Sierra Chichinautzin Volcanic Field near México City. Pelagatos (3020 m.a.s.l.) is a small scoria cone (0.0017 km 3) with lava flows (0.036 km 3) that covered an area of 4.9 km 2. Cerro del Agua scoria cone (3480 m.a.s.l., 0.028 km 3) produced several lava flows (0.24 km 3) covering an area of 17.6 km 2. Dos Cerros is a lava shield which covers an area of 80.3 km 2 and is crowned by two scoria cones: Tezpomayo (3080 m.a.s.l., 0.022 km 3) and La Ninfa (3000 m.a.s.l., 0.032 km 3). The eruptions of Cerro del Agua and Pelagatos occurred between 2500 and 14,000 yr BP. The Dos Cerros eruption took place close to 14,000 yr BP as constrained by radiocarbon dating. Rocks from these three volcanoes are olivine-hypersthene normative basaltic andesites and andesites with porphyritic, aphanitic, and glomeroporphyritic textures. Their mineral assemblages include olivine, clinopyroxene, and orthopyroxene phenocrysts (≤ 10 vol.%) embedded in a trachytic groundmass which consists mainly of plagioclase microlites and glass. Pelagatos rocks also present quartz xenocrysts. Due to their high Cr and Ni contents, and high Mg#s, Pelagatos rocks are considered to be derived from primitive magmas, hence the importance of this volcano for understanding petrogenetic processes in this region. Major and trace element abundances and petrography of products from these volcanoes indicate a certain degree of crystal fractionation during ascent to the surface. However, the magmas that formed the volcanoes evolved independently from each other and are not cogenetically related. REE, HFSE, LILE, and isotopic (Sr, Nd, and Pb) compositions point towards a heterogeneous mantle source that has been metasomatized by aqueous/melt phases from the subducted Cocos slab. There is no clear evidence of important crustal contributions in the compositions of Pelagatos and

  16. Resilience of the health team in caring for people with mental disorders in a psychiatric hospital.

    PubMed

    Brolese, Débora Felippe; Lessa, Greice; Santos, José Luís Guedes Dos; Mendes, Jucimara da Silva; Cunha, Kamylla Santos da; Rodrigues, Jeferson

    2017-08-17

    Evaluating and understanding the resilience process of the health team in caring for people with mental disorders in a psychiatric hospital. A mixed-method study with concomitant triangulation of data from a cross-sectional study, with health professionals, and Grounded Theory in the data. Quantitative data were collected using the Resilience Scale and analyzed using descriptive and inferential statistics. Qualitative data were obtained from interviews and analyzed using initial and focused coding. 40 health professionals participated in the study. Mean responses of the participants in the resilience scale were 99.80 ± 12.86 points, with a minimum of 35 and a maximum of 114 points. From the qualitative data, we can highlight the professionals' commitment in developing competencies in caring for people with mental disorders; valorization of teamwork and positive impact on work for the re-signification of the meaning of life. Understanding this process of resilience enables developing strategies to improve the quality of life of workers in psychiatric hospitals. Avaliar e compreender o processo de resiliência da equipe de saúde no cuidado a pessoas com transtornos mentais em um hospital psiquiátrico. Estudo de método misto com triangulação concomitante de dados de um estudo transversal, com profissionais de saúde, e uma Teoria Fundamentada nos Dados. Os dados quantitativos foram coletados a partir da Escala de Resiliência e analisados por meio de estatística descritiva e inferencial. Os dados qualitativos foram obtidos a partir de entrevistas e analisados mediante codificação inicial e focalizada. Participaram da pesquisa 40 profissionais de saúde. Na escala de resiliência, a média das respostas dos participantes foi 99,80±12,86 pontos, o mínimo foi de 35 e o máximo de 114 pontos. Nos dados qualitativos, destacaram-se o empenho dos profissionais para o desenvolvimento de competências para o cuidado de pessoas com transtornos mentais, a valoriza

  17. Osteobiographic analysis of skeleton I, Sítio Toca dos Coqueiros, Serra da Capivara National Park, Brazil, 11,060 BP: first results.

    PubMed

    Lessa, Andrea; Guidon, Niéde

    2002-06-01

    This paper presents an osteobiographic analysis of a single skeleton found in a small rock shelter known as Toca dos Coqueiros, Piauí, Brazil. This find is of interest because of an exceptionally old radiocarbon date associated with it. The date (11,060 BP) was obtained from charcoal associated directly with the skeleton. This is an interesting find because of the rarity of osteobiographic studies of skeletons of such antiquity. Despite the existence of two projectile points in association with the burial, the morphological and molecular analyses of the skeleton demonstrated that this was a female. She was about 35-45 years of age at death. The skeleton exhibited acute and chronic bone lesions. Oral pathology was also observed, including an interproximal dental groove, probably caused by the therapeutic use of a cactus thorn. This could be one of the oldest cases of an analgesic plant used in the prehistoric Americas.

  18. Occurrence of Aglae caerulea Lepeletier & Serville (Hymenoptera: Apidae: Euglossini) in the Parque Nacional da Chapada dos Guimarães, Mato Grosso State, Brazil.

    PubMed

    dos Anjos-Silva, Evandson J; Camillo, Evandro; Garófalo, Carlos A

    2006-01-01

    In a study conducted in the gallery forest of the Vale doVeu de Noiva in the Parque Nacional da Chapada dos Guimarães, Mato Grosso state, chemical baits were used to attract and sample male orchid bees. From September 2003 to July 2005, male euglossine bees were captured monthly, from 8:00 a.m. to 4:00 p.m. as they arrived at the baits. Of the 264 males captured, eight males belonged to Aglae caerulea Lepeletier & Serville, a cleptoparasitic euglossine species that presumably occurred only in the Amazon basin. Therefore, the occurrence of A. caerulea in this study area extends its geographical distribution range by approximately 2,400 km southwards in South America, as it is now recorded in both the Amazon and Platina basins.

  19. Feeding ecology of the lizard Tropidurus oreadicus Rodrigues 1987 (Tropiduridae) at Serra dos Carajás, Pará state, northern Brazil.

    PubMed

    Rocha, C F D; Siqueira, C C

    2008-02-01

    Tropidurus species commonly prey on arthropods, but they may also feed on vertebrates and plant material. The lizard Tropidurus oreadicus (Tropiduridae) is common in open vegetation habitats and generally has sexual dimorphism. In this study we analyzed the diet of T. oreadicus at Serra dos Carajás, Pará, in the north of Brazil. Snout-vent length (SVL) and jaw width (JW) were taken for 34 lizards. There was a significant difference in SVL and in JW, with males being larger than females. All lizards analyzed contained food in their stomachs. The diet of T. oreadicus at Serra dos Carajás was characterized by the consumption of a relative wide spectrum of food item categories (21 types of items), consisting of arthropods, part of one vertebrate and plant material, which characterizes the diet of a generalist predator. Volumetrically, the most important items in the diet of both sexes of T. oreadicus were flowers (M = 61.7%; F = 33%) and orthopterans (M = 1.7%; F = 3.5%). Ants were the most frequently consumed (100% for both sexes) and the most numerous (M = 94.5%; F = 89.4%) food item. Flowers also were frequently consumed (M = 91.7%; F = 54.5%), with their relative consumption differing significantly between sexes. There was not a significant sexual difference in prey volume, neither in number of preys per stomach, nor in type of prey ingested. There was no relationship between lizard jaw width and the mean volume of prey. The data showed that T. oreadicus is a relatively generalist lizard in terms of diet and that consumes large volumes of plant material, especially flowers of one species of genus Cassia.

  20. Geochemistry of upland lacustrine sediments from Serra dos Carajás, Southeastern Amazon, Brazil: Implications for catchment weathering, provenance, and sedimentary processes

    NASA Astrophysics Data System (ADS)

    Sahoo, Prafulla Kumar; Felix Guimarães, José Tasso; Martins Souza-Filho, Pedro Walfir; Sousa da Silva, Marcio; Maurity, Clovis Wagner; Powell, Mike A.; Rodrigues, Tarcísio Magevski; Fonseca da Silva, Delmo; Mardegan, Sílvia Fernanda; Furtini Neto, Antonio Eduardo; Dall'Agnol, Roberto

    2016-12-01

    A multi-proxy geochemical study of surficial sediments of an upland lake (Amendoim Lake), located in the Serra dos Carajás region, Brazil, was carried out to understand catchment weathering and provenance of sediments in the basin, as well as sedimentary processes. The carbon and nitrogen isotopic compositions of organic matter in the sediment were quite homogeneous, and suggest that the organic sources for this lake are mainly composed of palms and submerged macrophytes. The R-mode factor analysis indicates that most of the trace elements, including rare earth elements (REEs), are clustered with Al (Group 1), Si is grouped with Zr and Hf (Group 4), total organic carbon (TOC) with TS and Hg (Group 2), and Fe with Mn and As (Group 3). The elements of the Group 1 show strong positive correlations with Al, suggesting that these elements are hosted in detrital minerals during laterization in the catchment basin and not significantly affected by diagenesis. The high CIA values (96-99) of sediments together with their position in A-CN-K and log (Fe2O3/K2O) vs log (SiO2/Al2O3) plots indicate intense chemical weathering in source area. However, similar geochemical signatures between lake sediments and catchment lateritic crust indicates that mechanical erosion was the dominant sediment formation process. REE patterns normalized to chondrite along with geochemical indices (Al/K, Al/Ti, La/Th, La/Al, Ti/Zr, Zr/Hf, Th/Sc, Co/Th, Ba/Sr, and Eu/Eu*) also indicate that the sediments are mainly derived from laterite crust. This study provides reliable background information to reconstruct weathering processes and lake evolution in the Serra dos Carajás area.

  1. Diet of Ameerega braccata (Steindachner, 1864) (Anura: Dendrobatidae) from Chapada dos Guimarães and Cuiabá, Mato Grosso State, Brazil.

    PubMed

    Forti, L R; Tissiani, A S O; Mott, T; Strüssmann, C

    2011-02-01

    The understanding of feeding habits is important for anurans in general, both from an ecological and a phylogenetic perspective. For diurnal poison frogs belonging to the Dendrobatidae family, diet aspects play a crucial role in their defense and survival. Herein, we investigated feeding habits, foraging behaviour, and overall effects of habitat, sex, and body size on the diet of individuals of Ameerega braccata, a poorly known dendrobatid species. Specimens were observed and collected in the type-locality, Chapada dos Guimarães, and in the neighbouring municipality of Cuiabá, both in the State of Mato Grosso, Midwestern Brazil. The most important prey categories for A. braccata were Formicidae, Isoptera, and Acari, whose representatives were caught during active foraging. Individuals from Chapada dos Guimarães population consumed more Acari but fewer Isoptera than individuals from Cuiabá. Despite this, niche breadth values were narrow and similar for the two populations. Individuals from two distinct habitats (campo sujo and cerrado stricto sensu) showed differences in their diet, probably as an effect of differential prey availability. Females consumed more Isoptera than males. The number of prey categories used as food was not influenced by the variation of body size of the target species. However, the abundance and the volume of consumed Acari were statistically correlated with body size. The main results suggest that Ameerega braccata has a narrow niche breadth, as well as a specialised diet in ants, termites, and mites, which reinforces the hypotheses of close association between Acari consumption and the presence of skin toxic alkaloids, already found in other species of Dendrobatidae. Although differences in prey consumption between sexes are uncommon among poisonous frogs, differences in the diet composition between age classes, which probably reduce intraspecific competition, are frequently reported.

  2. Novel vaccine potential of Rv3131, a DosR regulon-encoded putative nitroreductase, against hyper-virulent Mycobacterium tuberculosis strain K.

    PubMed

    Kwon, Kee Woong; Kim, Woo Sik; Kim, Hongmin; Han, Seung Jung; Hahn, Mi-Young; Lee, Jong Seok; Nam, Ki Taek; Cho, Sang-Nae; Shin, Sung Jae

    2017-03-08

    Accumulating evidence indicates that latency-associated Mycobacterium tuberculosis (Mtb)-specific antigens from the dormancy survival regulator regulon (DosR) may be promising novel vaccine target antigens for the development of an improved tuberculosis vaccine. After transcriptional profiling of DosR-related genes in the hyper-virulent Beijing Mtb strain K and the reference Mtb strain H37Rv, we selected Rv3131, a hypothetical nitroreductase, as a vaccine antigen and evaluated its vaccine efficacy against Mtb K. Mtb K exhibited stable and constitutive up-regulation of rv3131 relative to Mtb H37Rv under three different growth conditions (at least 2-fold induction) including exponential growth in normal culture conditions, hypoxia, and inside macrophages. Mice immunised with Rv3131 formulated in GLA-SE, a well-defined TLR4 adjuvant, displayed enhanced Rv3131-specific IFN-γ and serum IgG2c responses along with effector/memory T cell expansion and remarkable generation of Rv3131-specific multifunctional CD4(+) T cells co-producing TNF-α, IFN-γ and IL-2 in both spleen and lung. Following challenge with Mtb K, the Rv3131/GLA-SE-immunised group exhibited a significant reduction in bacterial number and less extensive lung inflammation accompanied by the obvious persistence of Rv3131-specific multifunctional CD4(+) T cells. These results suggest that Rv3131 could be an excellent candidate for potential use in a multi-antigenic Mtb subunit vaccine, especially against Mtb Beijing strains.

  3. Novel vaccine potential of Rv3131, a DosR regulon-encoded putative nitroreductase, against hyper-virulent Mycobacterium tuberculosis strain K

    PubMed Central

    Kwon, Kee Woong; Kim, Woo Sik; Kim, Hongmin; Han, Seung Jung; Hahn, Mi-Young; Lee, Jong Seok; Nam, Ki Taek; Cho, Sang-Nae; Shin, Sung Jae

    2017-01-01

    Accumulating evidence indicates that latency-associated Mycobacterium tuberculosis (Mtb)-specific antigens from the dormancy survival regulator regulon (DosR) may be promising novel vaccine target antigens for the development of an improved tuberculosis vaccine. After transcriptional profiling of DosR-related genes in the hyper-virulent Beijing Mtb strain K and the reference Mtb strain H37Rv, we selected Rv3131, a hypothetical nitroreductase, as a vaccine antigen and evaluated its vaccine efficacy against Mtb K. Mtb K exhibited stable and constitutive up-regulation of rv3131 relative to Mtb H37Rv under three different growth conditions (at least 2-fold induction) including exponential growth in normal culture conditions, hypoxia, and inside macrophages. Mice immunised with Rv3131 formulated in GLA-SE, a well-defined TLR4 adjuvant, displayed enhanced Rv3131-specific IFN-γ and serum IgG2c responses along with effector/memory T cell expansion and remarkable generation of Rv3131-specific multifunctional CD4+ T cells co-producing TNF-α, IFN-γ and IL-2 in both spleen and lung. Following challenge with Mtb K, the Rv3131/GLA-SE-immunised group exhibited a significant reduction in bacterial number and less extensive lung inflammation accompanied by the obvious persistence of Rv3131-specific multifunctional CD4+ T cells. These results suggest that Rv3131 could be an excellent candidate for potential use in a multi-antigenic Mtb subunit vaccine, especially against Mtb Beijing strains. PMID:28272457

  4. Conversion of a heme-based oxygen sensor to a heme oxygenase by hydrogen sulfide: effects of mutations in the heme distal side of a heme-based oxygen sensor phosphodiesterase (Ec DOS).

    PubMed

    Du, Yongming; Liu, Gefei; Yan, Yinxia; Huang, Dongyang; Luo, Wenhong; Martinkova, Marketa; Man, Petr; Shimizu, Toru

    2013-10-01

    The heme-based oxygen-sensor phosphodiesterase from Escherichia coli (Ec DOS), is composed of an N-terminal heme-bound oxygen sensing domain and a C-terminal catalytic domain. Oxygen (O2) binding to the heme Fe(II) complex in Ec DOS substantially enhances catalysis. Addition of hydrogen sulfide (H2S) to the heme Fe(III) complex in Ec DOS also remarkably stimulates catalysis in part due to the heme Fe(III)-SH and heme Fe(II)-O2 complexes formed by H2S. In this study, we examined the roles of the heme distal amino acids, M95 (the axial ligand of the heme Fe(II) complex) and R97 (the O2 binding site in the heme Fe(II)-O2 complex) of the isolated heme-binding domain of Ec DOS (Ec DOS-PAS) in the binding of H2S under aerobic conditions. Interestingly, R97A and R97I mutant proteins formed an oxygen-incorporated modified heme, verdoheme, following addition of H2S combined with H2O2 generated by the reactions. Time-dependent mass spectroscopic data corroborated the findings. In contrast, H2S did not interact with the heme Fe(III) complex of M95H and R97E mutants. Thus, M95 and/or R97 on the heme distal side in Ec DOS-PAS significantly contribute to the interaction of H2S with the Fe(III) heme complex and also to the modification of the heme Fe(III) complex with reactive oxygen species. Importantly, mutations of the O2 binding site of the heme protein converted its function from oxygen sensor to that of a heme oxygenase. This study establishes the novel role of H2S in modifying the heme iron complex to form verdoheme with the aid of reactive oxygen species.

  5. Humoral Responses to Rv1733c, Rv0081, Rv1735c, and Rv1737c DosR Regulon-Encoded Proteins of Mycobacterium tuberculosis in Individuals with Latent Tuberculosis Infection

    PubMed Central

    Nalwoga, Angela; Levin, Jonathan; Ottenhoff, Tom H. M.; Elliott, Alison M.; Cose, Stephen; Andia-Biraro, Irene

    2017-01-01

    Latent tuberculosis infection (LTBI) is evidence of immunological control of tuberculosis. Dormancy survival regulator (DosR) regulon-encoded proteins may have a role in the maintenance of LTBI. T cell responses to Rv1733c, Rv0081, Rv1735c, and Rv1737c DosR regulon-encoded proteins were found to be most frequent among household contacts of TB cases from Uganda compared to other DosR proteins, but antibody responses were not described. We characterized antibody responses to these proteins in individuals from Uganda. Antibodies to Rv1733c, Rv0081, Rv1735c, and Rv1737c DosR regulon-encoded proteins were measured in 68 uninfected individuals, 62 with LTBI, and 107 with active pulmonary tuberculosis (APTB) cases. There were no differences in the concentrations of antibodies to Rv0081, Rv1735c, and Rv1737c DosR regulon-encoded proteins between individuals with LTBI and APTB and those who were uninfected. LTBI was associated with higher concentrations of antibodies to Rv1733c in female participants [adjusted geometric mean ratio: 1.812, 95% confidence interval (CI): 1.105 2.973, and p = 0.019] but not in males (p value for interaction = 0.060). Antibodies to the four DosR regulon-encoded proteins investigated may not serve as good biomarkers of LTBI in the general population. More of the M.tb proteome needs to be screened to identify proteins that induce strong antibody responses in LTBI. PMID:28255560

  6. A estabilidade dos PAHS em função da energia da radiação interestelar nas faixas UV e raios-X

    NASA Astrophysics Data System (ADS)

    Pinotti, R.; Costa, R. K.; Boechat-Roberty, H. M.; Lago, A.; Souza, G. B.

    2003-08-01

    A nebulosa CRL 618, uma proto-nebulosa planetária cuja nuvem molecular espessa envolve uma estrela B0, contém uma grande quantidade de C2H2 e CH4. Estas moléculas são consideradas os tijolos da criação de grandes moléculas carbonadas como os Hidrocarbonetos Policíclicos Aromáticos (PAHs). Esta nebulosa, por estar exposta a intensos campos de UV e Raios-X, é uma região de fotodissociação molecular que propicia a formação de novas moléculas, confirmada pela presença de C4H2 e C6H6 (Benzeno), que é a unidade básica dos PAHs. Atribui-se a esta família de moléculas orgânicas duas propriedades fundamentais, a resistência para sobreviver ao campo de radiação UV interestelar e a geração das bandas de emissão não identificadas (UIR) observadas no infravermelho. No entanto, alguns autores questionam a resistência dos PAHs ao campo de radiação UV interestelar. Empregando a técnica de Espectrometria de Massas por Tempo de Vôo, no modo de coincidência fotoelétron-fotoíon, estudamos a ionização e fragmentação das seguintes moléculas: Benzeno, Benzeno deuterado, Naftaleno, Antraceno e Fenantreno. Utilizamos uma fonte de Hélio monocromática em 21,21 eV (584,5 Å) e a radiação Síncroton do Laboratório Nacional de Luz Síncroton (LNLS) em diferentes energias nas proximidades da borda do C 1s ( 290 eV). Comprovamos a estabilidade dos PAHs sob ação de UV (21,21 eV), onde eles apresentam um baixo nível de fotodissociação, produzindo fragmentos ionizados com rendimento total na ordem de 5 por cento em relação ao íon molecular pai. Entretanto, em altas energias, na faixa de Raios-X, a quebra destas moléculas torna-se mais intensa, com a produção de muitos fragmentos. Como uma das rotas de fragmentação do Naftaleno é [(C10H8) = > (C6H6+) + (C4H2) + (e-)], e como temos as evidências observacionais da existência do C4H2 e C6H6 na nebulosa CRL 618, sugerimos que este ambiente também possui o Naftaleno.

  7. Mycobacterium tuberculosis DevR/DosR Dormancy Regulator Activation Mechanism: Dispensability of Phosphorylation, Cooperativity and Essentiality of α10 Helix

    PubMed Central

    Sharma, Saurabh; Tyagi, Jaya Sivaswami

    2016-01-01

    DevR/DosR is a well-characterized regulator in Mycobacterium tuberculosis which is implicated in various processes ranging from dormancy/persistence to drug tolerance. DevR induces the expression of an ~48-gene dormancy regulon in response to gaseous stresses, including hypoxia. Strains of the Beijing lineage constitutively express this regulon, which may confer upon them a significant advantage, since they would be ‘pre-adapted’ to the environmental stresses that predominate during infection. Aerobic DevR regulon expression in laboratory-manipulated overexpression strains is also reported. In both instances, the need for an inducing signal is bypassed. While a phosphorylation-mediated conformational change in DevR was proposed as the activation mechanism under hypoxia, the mechanism underlying constitutive expression is not understood. Because DevR is implicated in bacterial dormancy/persistence and is a promising drug target, it is relevant to resolve the mechanistic puzzle of hypoxic activation on one hand and constitutive expression under ‘non-inducing’ conditions on the other. Here, an overexpression strategy was employed to elucidate the DevR activation mechanism. Using a panel of kinase and transcription factor mutants, we establish that DevR, upon overexpression, circumvents DevS/DosT sensor kinase-mediated or small molecule phosphodonor-dependent activation, and also cooperativity-mediated effects, which are key aspects of hypoxic activation mechanism. However, overexpression failed to rescue the defect of C-terminal-truncated DevR lacking the α10 helix, establishing the α10 helix as an indispensable component of DevR activation mechanism. We propose that aerobic overexpression of DevR likely increases the concentration of α10 helix-mediated active dimer species to above the threshold level, as during hypoxia, and enables regulon expression. This advance in the understanding of DevR activation mechanism clarifies a long standing question as to

  8. Mycobacterium tuberculosis DevR/DosR Dormancy Regulator Activation Mechanism: Dispensability of Phosphorylation, Cooperativity and Essentiality of α10 Helix.

    PubMed

    Sharma, Saurabh; Tyagi, Jaya Sivaswami

    2016-01-01

    DevR/DosR is a well-characterized regulator in Mycobacterium tuberculosis which is implicated in various processes ranging from dormancy/persistence to drug tolerance. DevR induces the expression of an ~48-gene dormancy regulon in response to gaseous stresses, including hypoxia. Strains of the Beijing lineage constitutively express this regulon, which may confer upon them a significant advantage, since they would be 'pre-adapted' to the environmental stresses that predominate during infection. Aerobic DevR regulon expression in laboratory-manipulated overexpression strains is also reported. In both instances, the need for an inducing signal is bypassed. While a phosphorylation-mediated conformational change in DevR was proposed as the activation mechanism under hypoxia, the mechanism underlying constitutive expression is not understood. Because DevR is implicated in bacterial dormancy/persistence and is a promising drug target, it is relevant to resolve the mechanistic puzzle of hypoxic activation on one hand and constitutive expression under 'non-inducing' conditions on the other. Here, an overexpression strategy was employed to elucidate the DevR activation mechanism. Using a panel of kinase and transcription factor mutants, we establish that DevR, upon overexpression, circumvents DevS/DosT sensor kinase-mediated or small molecule phosphodonor-dependent activation, and also cooperativity-mediated effects, which are key aspects of hypoxic activation mechanism. However, overexpression failed to rescue the defect of C-terminal-truncated DevR lacking the α10 helix, establishing the α10 helix as an indispensable component of DevR activation mechanism. We propose that aerobic overexpression of DevR likely increases the concentration of α10 helix-mediated active dimer species to above the threshold level, as during hypoxia, and enables regulon expression. This advance in the understanding of DevR activation mechanism clarifies a long standing question as to the

  9. Novas determinações dos parâmetros atmosféricos das estrelas anãs brancas DA

    NASA Astrophysics Data System (ADS)

    Giovannini, O.; Costa, A. F. M.; Kepler, S. O.

    2003-08-01

    Nós temos selecionado uma amostra de estrelas anãs brancas DA (atmosfera de hidrogênio) a partir dos índices de Strömgren cujos valores estão próximos a região de instabilidade das estrelas anãs brancas DA variáveis, as chamadas estrelas DAV ou ZZ Ceti. O objetivo é determinar os parâmetros fundamentais (temperatura efetiva, Teff, aceleração da gravidade, log g, e massa) destas estrelas para verificar quais os parâmetros estelares estão envolvidos com o mecanismo de pulsação das estrelas DAV. Nós obtemos, até agora, mais de 120 espectros óticos de estrelas DA. Entre as estrelas selecionadas há 20 estrelas variáveis (DAV). Assim, podemos verificar se existem ou não estrelas não variáveis dentro da faixa de instabilidade das estrelas ZZ Ceti. Neste trabalho nós apresentamos a determinação dos parâmetros atmosféricos (temperatura efetiva, Teff, e aceleração da gravidade, log g) das estrelas anãs brancas DA usando os novos modelos de atmosfera ML2/a = 0.6. Estes modelos têm sido utilizados recentemente por fornecerem uma excelente consistência interna na determinação das temperaturas nas regiões do ultra-violeta e ótico. Os parâmetros atmosféricos são determinados espectroscopicamente através da comparação do fluxo de energia das linhas de Balmer (Hb à H9) entre os espectros observados e sintéticos (gerados pelos modelos de atmosfera). As temperaturas obtidas com os novos modelos são, em geral, menores (~ 1000 K menos) que as temperaturas determinadas anteriormente, com modelos ML1. Os valores de log g não mudaram significativamente (menos de 10%). A faixa de instabilidade das DAVs está entre 11000 e 13000 K, consistente com dados de outros autores.

  10. [Unified National Health System costs in São José dos Campos, São Paulo State, Brazil, for hospital admissions due to external causes].

    PubMed

    Melione, Luís Paulo Rodrigues; Mello-Jorge, Maria Helena Prado de

    2008-08-01

    The objective of this study was to identify direct expenditures for hospitalizations due to external causes in the Unified National Health System (SUS) in the city of São José dos Campos, São Paulo State, Brazil. Admissions to the Dr. José de Carvalho Florence Municipal Hospital resulting from external causes or injuries - ICD-10, chapters XIX and XX respectively - were analyzed for the first semester of 2003. 976 patient admission forms were analyzed, after data evaluation. Admissions with the highest total cost were those resulting from motor vehicle accidents and falls. The highest mean cost for hospitalization for injury was due to motor vehicle accidents (BRL 614.63), followed by assault (BRL 594.90). The highest mean cost for hospitalization due to injury was for cervical fractures (BRL 1,191.42) and head injuries (BRL 1,000.44). Hospitalizations with the highest daily cost were skull and facial fractures (BRL 166.72) and abdominal trauma (BRL 148.26). The study confirmed that motor vehicle accidents, falls, and assault are an important source of costs due to hospitalization for injuries.

  11. Analysis of the Astronomical Concepts Presented by Teachers of Science, Physics, and Mathematics of São José dos Campos / SP Municipality

    NASA Astrophysics Data System (ADS)

    Pereira Gonzaga, Edson; Voelzke, Marcos Rincon

    2013-11-01

    The aim of this work is to conduct a survey of alternative conceptions about the basic concepts of Astronomy from schoolteachers in the City of São José dos Campos. This study covers the the state-run education system and complies with legal documents related to the curriculum of educational systems, such as the Curriculum of São Paulo State and the Parameters of the National Curriculum (PCN). Alternative conceptions, mentioned in Langhi (2009) as very important, were used, because it is believed that if a student can learn these concepts before the methodological intervention, it is possible to prepare contextualized presentations for teachers, and consequently students, to compare what they already know with the new information they obtain in the sessions at the digital mobile planetarium (DMP) of the Universidade Cruzeiro do Sul. Afterwards, they may discuss in a forum, in the form of debate, seeking to draw conclusions relevant to the topic, and transmitting the same to students in Basic Education (EB). This is a case study with a quantitative survey and a qualitative analysis of data on astronomical concepts collected through two questionnaires, one before and one after the intervention, respecting the implementation period of the study,- here called methodological intervention of content presentations at the mobile planetarium - and on respective discussions.

  12. Implementing a Knowledge Translation Intervention in Long-Term Care: Feasibility Results From the Vitamin D and Osteoporosis Study (ViDOS)

    PubMed Central

    Kennedy, Courtney C.; Thabane, Lehana; Ioannidis, George; Adachi, Jonathan D.; Papaioannou, Alexandra

    2016-01-01

    Objectives To evaluate the feasibility of implementing an interdisciplinary, multifaceted knowledge translation intervention within long-term care (LTC) and to identify any challenges that should be considered in designing future studies. Design Cluster randomized controlled trial. Setting Forty LTC homes across the province of Ontario, Canada. Participants LTC teams composed of physicians, nurses, pharmacists, and other staff. Measurements Cluster-level feasibility measures, including recruitment, retention, data completion, and participation in the intervention. A process evaluation was completed by directors of care indicating which process/policy changes had been implemented. Results Recruitment and retention rates were 22% and 63%, respectively. Good fidelity with the intervention was achieved, including attendance at educational meetings. After ViDOS, 7 process indicators were being newly implemented by more than 50% of active intervention homes. Conclusion Despite recruitment and retention challenges, the multifaceted intervention produced a number of policy/process changes and had good intervention fidelity. This study is registered at ClinicalTrials.gov NCT01398527. PMID:24953541

  13. ASPECTS OF THE ECOLOGY OF PHLEBOTOMINES (Diptera: Psychodidae: Phlebotominae) IN AN AREA OF CUTANEOUS LEISHMANIASIS OCCURRENCE, MUNICIPALITY OF ANGRA DOS REIS, COAST OF RIO DE JANEIRO STATE, BRAZIL

    PubMed Central

    de Aguiar, Gustavo Marins; de Azevedo, Alfredo Carlos Rodrigues; de Medeiros, Wagner Muniz; Alves, João Ricardo Carreira; Rendeiro, Vanessa

    2014-01-01

    Over a complete two-year period, phlebotomine specimens were caught in an area of cutaneous leishmaniasis occurrence in the municipality of Angra dos Reis. A manual suction tube was used to catch phlebotomines on house walls, and also light traps in domestic and peridomestic settings and in the forest. This yielded 14,170 specimens of 13 species: two in the genus Brumptomyia and eleven in the genus Lutzomyia. L. intermedia predominantly in domestic and peridomestic settings, with little presence in the forest, with the same trend being found in relation to L. migonei, thus proving that these species have adapted to the human environment. L. fischeri appeared to be eclectic regarding location, but was seen to be proportionally more endophilic. L. intermedia and L. migonei were more numerous in peridomestic settings, throughout the year, while L. fischeri was more numerous in domestic settings except in March, April, May and September. From the prevalence of L. intermedia, its proven anthropophily and findings of this species naturally infected with Leishmania (Viannia) braziliensis, it can be incriminated as the main vector for this agent of cutaneous leishmaniasis in the study area, especially in the peridomestic environment. L. fischeri may be a coadjuvant in carrying the parasite. PMID:24626417

  14. Combined use of aerogammaspectrometry and geochemistry to access sediment sources in a shallow coral site at Armação dos Búzios, Brazil

    NASA Astrophysics Data System (ADS)

    Godiva, Danielly; Evangelista, Heitor; Kampel, Milton; Licinio, Marcus Vinicius; Munita, Casimiro

    2010-05-01

    Coral and reef environments in shallow waters are negatively affected by human activities in several coastal areas worldwide. It has been demonstrated that sediment influx and macronutrient discharges induce decline of coral population structure and diversity. Therefore, efforts to quantify sediment flux, sources and the biological response to sedimentation were conducted by several marine researchers. Herein, we investigated the case study of Armação dos Búzios/Brazil/Western South Atlantic, where coral colonies (mostly Siderastrea stellata) are under stress due to sediment apportionment as a consequence of regional human occupation. Classification of potential sediment source regions was based on a high-resolution aerogammaspectrometry survey for 232Th, 238U and 40K in main land near shore, used as primarily tool, in combination with sediment geochemistry. This approach allowed distinguishing three hydrographic basins (Macaé river basin, São João river basin and Una river basin) as potential sources. Hierarchical cluster analysis applied to the set of parameters identified the Macaé River as the most probable sediment contributor to the coralline site.

  15. Seroprevalence of Rickettsia bellii and Rickettsia felis in dogs, São José dos Pinhais, State of Paraná, Brazil.

    PubMed

    Fortes, Fernanda Silva; Silveira, Iara; Moraes-Filho, Jonas; Leite, Ronaldo Viana; Bonacim, José Edivaldo; Biondo, Alexander Welker; Labruna, Marcelo Bahia; Molento, Marcelo Beltrão

    2010-01-01

    Brazilian spotted fever (BSF) is a vector-borne zoonosis caused by Rickettsia rickettsii bacteria. Dogs can be host sentinels for this bacterium. The aim of the study was to determine the presence of antibodies against Rickettsia spp. in dogs from the city of São José dos Pinhais, State of Paraná, Southern Brazil, where a human case of BSF was first reported in the state. Between February 2006 and July 2007, serum samples from 364 dogs were collected and tested at 1:64 dilutions by indirect immunofluorescence assay (IFA) against R. rickettsii and R. parkeri. All sera that reacted at least to one of Rickettsia species were tested against the six main Rickettsia species identified in Brazil: R. rickettsii, R. parkeri, R. bellii, R. rhipicephali, R. amblyommii and R. felis. Sixteen samples (4.4%) reacted to at least one Rickettsia species. Among positive animals, two dogs (15.5%) showed suggestive titers for R. bellii exposure. One sample had a homologous reaction to R. felis, a confirmed human pathogen. Although Rickettsia spp. circulation in dogs in the area studied may be considered at low prevalence, suggesting low risk of human infection, the present data demonstrate for the first time the exposure of dogs to R. bellii and R. felis in Southern Brazil.

  16. [Ecological aspects of phlebotomus of the Parque Nacional da Serra dos Orgãos, Rio de Janeiro. I. Monthly frequency in human baits (Diptera, Psychodidae, Phlebotominae)].

    PubMed

    de Aguiar, G M; Soucasaux, T

    1984-01-01

    During two full years--from October 1980 to September 1982--we captured sandflies in the National Park of Serra dos Orgãos, State of Rio de Janeiro, Brazil. The captures, with human bait, were carried out weekly, each with a duration of two hours, and at three different times (6 to 8 a.m., 5 to 7 a.m. and 7:30 to 9:30 p.m.). In every capture, we recorded the phase of the moon and, at each hour, the temperature, relative humidity, wind and rain. In 586 hours 4,834 sandflies of ten species were captured, all belonging to genus Lutzomyia França, 1924. L. ayrozai and L. hirsuta represented 92% of the total species captured. However, they were dominant at different times, the former being more frequent in the warm and wet months, and considerably declining in the cold and dry months, in which the latter gradually prevailed. L. fischeri and L. shannoni were shown to be the most resistant to unfavourable weather conditions. Whenever there was any rain or wind, they were, in general, the only species captured. With regard to lunar cycle, we observed that new moon was the most favourable phase for the capture of sandflies and full moon the one with the smallest yield, except for L. shannoni which occurred more frequently during this period.

  17. Uma Visão do Universo Segundo um Grupo de Alunos do Ensino Médio de São Paulo

    NASA Astrophysics Data System (ADS)

    Elias, D. S.; Araújo, M.; Amaral, L. H.; Voelzke, M. R.; Araújo, M.

    2005-08-01

    A astronomia, embora seja uma ciência popular, com inúmeras descobertas de interesse público, ainda é apresentada desconsiderando-se os aspectos históricos e científicos relacionados ao seu desenvolvimento, sendo geralmente veiculada nos meios de comunicação de maneira pouco esclarecedora e não raro com imprecisões. Neste trabalho analisou-se a concepção de um grupo de estudantes de Ensino Médio sobre conceitos de astronomia, visando identificar sua visão de mundo a respeito do Universo, envolvendo idéias sobre espaço e tempo. Para issso, foi aplicado um questionário em três escolas da grande São Paulo em um espaço amostral de 270 alunos. Constatou-se que, embora o ensino de astronomia esteja previsto nos PCNEM, os resultados obtidos na pesquisa mostram que há grande deficiência no conhecimento dos temas investigados. Nesse sentido, verificou-se que apenas 20% dos alunos eram capazes de relacionar a sucessão das semanas com as fases da lua, enquanto 28% associaram as estações do ano à inclinação do eixo de rotação da Terra. Por outro lado, somente 23% dos alunos tinham noções das distâncias entre os objetos celestes próximos da Terra e 56% conseguiram relacionar o Big Bang com a origem do Universo. Finalmente, constatou-se que 37% reconheciam o ano-luz como uma unidade de distância e 60% reconheciam o Sol como sendo uma estrela. Apesar de 60% dos alunos indicarem que a escola é a principal fonte para aquisição dos conhecimentos de astronomia, conclui-se que seus conceitos nessa área ainda são inadequados, havendo necessidade de ampliação e aprimoramento da abordagem desses conteúdos nos ambientes escolares.

  18. Parametric Analysis of Combustion of Porous Medium.

    DTIC Science & Technology

    1985-12-01

    Desenvolvimento 2 Ministerio da Aeronautica Brasilia , Brazil 2. Centro Tecnico Aeroespacial 2 Ministerio da Aeronau ica Sao Jose dos Campos , SP , Brazil 12200 3...Major Antonio C. S. Serapiao , Brazilien air force 3 Centro Tecnico Aeroespacial Sao Jose dos Campos , SP , Brazil 12200 4. Associate Professor David

  19. Resultados do desenvolvimento de um propulsor à plasma no Brasil

    NASA Astrophysics Data System (ADS)

    Ferreira, I. S.; Ferreira, J. L.

    2003-08-01

    Uma das partes mais importantes de um satélite é o controle de atitude do mesmo. E se tratando de um satélite científico, a atenção para este sistema deve ser redobrada. Uma possibilidade atraente para executar esta tarefa é a propulsão elétrica. Aqui, mostraremos resultados obtidos pelo propulsor à plasma PHALL-01, desenvolvido na Universidade de Brasília entre 2000 e 2003. Este é derivado do propulsor russo SPT-100 (Stationary Plasma Thruster), mas com o emprego inovador de um arranjo de imãs permanentes como fonte do campo magnético, este último o agente da aceleração do plasma. Esta alteração foi motivada pelo objetivo de que o mesmo operasse com o mínimo de potência elétrica. A partir da formulação teórica do mecanismo de aceleração, tendo como base as equações da magnetohidrodinâmica, pode-se obter vínculos sob os quais o propulsor pudesse ser construído. O mais forte destes é o que dita a topologia do campo magnético. Sendo assim, foram realizadas simulações computacionais, que definiram a geometria do propulsor. Após construído, este foi diagnosticado usando-se sondas de Langmuir e analisadores de energia. Como resultados, obtivemos a distribuição espacial da temperatura, densidade e potencial do plasma, bem como a distribuição angular do feixe produzido pelo mesmo em vários regimes de operação. O espectro de energia do feixe de plasma também foi medido, indicando íons de até 560eV. Combinando estes resultados, calculou-se o empuxo do propulsor: 84mN; e o impulso específico: 1083s. Estes demonstram que o mesmo estará qualificado, num futuro próximo, para o emprego no controle de atitude de satélites científicos, ou até mesmo como parte do conjunto propulsor primário, responsáveis pela transferência de órbitas.

  20. Ensino Medico e Desenvolvimento (Secondary Education and Development).

    ERIC Educational Resources Information Center

    Gouveia, Aparecida Joly; Havinghurst, Robert J.

    This document is an English-language abstract (approximately 1,500 words) of a study about secondary education with particular reference to students; it essentially treats the relationship between economics and education in the context of Brazilian society. From the sociological point of view; the study is characterized by concentration on certain…

  1. Techniques of remote sensing applied to the environmental analysis of part of an aquifer located in the São José dos Campos Region sp, Brazil.

    PubMed

    Bressan, Mariana Affonseca; Dos Anjos, Célio Eustáquio

    2003-05-01

    The anthropogenic activity on the surface can modify and introduce new mechanisms of recharging the groundwater system, modifying the tax, the frequency and the quality of recharge of underground waters. The understanding of these mechanisms and the correct evaluation of such modifications are fundamental in determining the vulnerability of groundwater contamination. The groundwater flow of the South Paraíba Compartment, in the region of São José dos Campos, São Paulo, is directly related to structural features of the Taubaté Basin and, therefore, the analysis of its behaviour enhances the understanding of tectonic structure. The methodology adopted for this work consists in pre-processing and processing of the satellite images, visual interpretation of HSI products, field work and data integration. The derivation of the main structural features was based on visual analysis of the texture elements of drainage, and the relief in sedimentary and crystalline rocks. Statistical analysis of the feature densities and the metric-geometric relations between the analysed elements have been conducted. The crystalline rocks, on which the sediments were laying, conditions and controls the structural arrangement of sedimentary formations. The formation of the South Paraíba Grabén is associated with Cenozoic distensive movement which reactivated old features of crust weakness and generated previous cycles with normal characteristics. The environmental analysis is based on the integration of the existing methodology to characterise vulnerability of an universal pollutant and density fracture zone. The digital integration was processed using GIS (Geographic Information System) to delineate five defined vulnerability classes. The hydrogeological settings were analysed in each thematic map and, using fuzzy logic, an index for each different vulnerability class was compiled. Evidence maps could be combined in a series of steps using map algebra.

  2. [Governance, sustainability, and equity in the health program for the municipality of São José dos Pinhais, Brazil].

    PubMed

    Bueno, Roberto Eduardo; Moysés, Simone Tetu; Bueno, Paula Alexandra Reis; Moysés, Samuel Jorge

    2013-12-01

    To analyze the Final Report of the VIII Health Conference and the São José dos Pinhais City Health Program for 2010-2013 and investigate whether these documents addressed the themes of sustainability, governance, and equity and the interfaces between these themes--government policies, power balance, and inclusive processes/impacting results--that make up the Concept Model for Human Development and Health Promotion developed by the authors. This case study analyzed 331 proposals approved for incorporation in the City Health Program. The six thematical categories of the Concept Model were analyzed using ATLAS Ti 5.0 software. The proposals were classified according to the number of themes and interfaces of the Concept Model: full health proposals contained all six categories; partial proposals contained three categories; and incipient proposals contained one category. Of 331 proposals approved, 162 (49%) contemplated the six thematical categories and were classified as full health promotion proposals. Ninety-five (29%) contemplated three categories (partial health promotion). Of these, 38 (12%) addressed Governance, Sustainability, and Government Policies, 33 (10%) addressed Governance, Power Balance, and Equity and 24 (7%) addressed Equity, Inclusive Processes/Impact Results, and Sustainability. Finally, 74 (22%) proposals contemplated only one category and were classified as incipient: 36 (11%) addressed Governance, 27 (8%) addressed sustainability, and 11 (3%) addressed equity. Based on the fact that 49% of the proposals approved were classified as full health promotion, it is considered that the effectiveness of social control and popular participation in the construction of health policies at the local level contritute to the promotion of health in the city.

  3. Prevalence of intestinal parasites versus knowledge, attitudes, and practices of inhabitants of low-income communities of Campos dos Goytacazes, Rio de Janeiro State, Brazil.

    PubMed

    de Moraes Neto, Antonio Henrique A; Pereira, Adriana P M F; Alencar, Maria de Fátima L; Souza, Paulo R B; Dias, Rodrigo C; Fonseca, Juliana G; Santos, Clóvis P; Almeida, João C A

    2010-07-01

    Intestinal parasites are the causative agents of common infections responsible for significant public health problems in developing countries and generally linked to lack of sanitation, safe water, and improper hygiene. More than two billion people throughout the world live with unrelenting illness due to intestinal parasitic infections (IPIs). The purposes of this study are to assess knowledge, attitudes, and practices on IPIs and investigate the relationship with prevalence of intestinal parasites among a low-income group of inhabitants from two communities of the Travessão District area, Campos dos Goytacazes, north of Rio de Janeiro State, Brazil. The two communities are known as "Parque Santuário," which is an urban slum with miserable living conditions, and "Arraial," where the socioeconomic and educational levels are better, neither having a sanitary infrastructure with an excreta collection system. Questionnaires revealed that both communities had local and specific codification to denominate the intestinal parasites and present correct knowledge on the theme but ignored some aspects of IPI transmission, with the Arraial population being better informed (p < 0.05). The overall prevalence of IPIs in Parque Santuário (49.7%) was greater than in Arraial (27.2%) (p < 0.001; prevalence ratio/95% confidence interval 1.83/1.50-2.23). This study reports the real IPI situation in the Travessão District and also reinforces the need to continue the investigation on the impact of combined prophylactic methods, educational measures, and socioeconomic and sanitary improvements by governmental authorities and the local popular organization.

  4. Diverging DOS strategy using an allene-containing tryptophan scaffold and a library design that maximizes biologically relevant chemical space while minimizing the number of compounds.

    PubMed

    Painter, Thomas O; Wang, Lirong; Majumder, Supriyo; Xie, Xiang-Qun; Brummond, Kay M

    2011-03-14

    A diverging diversity-oriented synthesis (DOS) strategy using an allene-containing tryptophan as a key starting material was investigated. An allene-yne substituted derivative of tryptophan 12 gave indolylmethylazabicyclooctadiene 17 when subjected to a microwave-assisted allenic [2 + 2] cycloaddition reaction. This same tryptophan-derived precursor afforded an indolylmethyldihydrocyclopentapyridinone 14 when subjected to a rhodium(I)-catalyzed cyclocarbonylation reaction and an indolylmethylpyrrolidinocyclopentenones 16 when reacted with molybdenum hexacarbonyl. Construction of allenic tetrahydro-β-carboline scaffolds via a Pictet-Spengler reaction and subsequent silver(I)-catalyzed cycloisomerization afforded tetrahydroindolizinoindoles (21). Attachment of allene and alkyne groups to the tetrahydro-β-carboline, followed by a microwave-assisted allenic [2 + 2] cycloaddition reaction, provided tetrahydrocyclobutaindoloquinolizinones 24 and the tetrahydrocyclopentenone indolizinoindolone 26 when reacted with molybdenum hexacarbonyl. These six scaffolds were used as templates for the construction of a virtual library of 11 748 compounds employing 44 indoles, 12 aldehydes, and 51 alkynes. Diversity analyses using a combination of cell-based chemistry space computations using BCUT (Burden (B) CAS (C) Pearlman at the University of Texas (UT)) metrics and Tanimoto coefficient (Tc) similarity calculations using two-dimensional (2D) fingerprints showed that the compounds in the virtual library occupied new chemical space when compared to the 327,000 compounds in the molecular libraries small molecule repository (MLSMR). A subset of fifty-three compounds was identified from the virtual library using the DVS package of Sybyl 8.0; this subset represents the most diverse compounds within the chemical space defined by these compounds and will be synthesized and screened for biological activity.

  5. Estudio fotométrico y espectroscópico de dos cúmulos abiertos jóvenes del disco con apariencia globular

    NASA Astrophysics Data System (ADS)

    Piatti, A. E.; Clariá, J. J.; Bica, E.

    Se presentan y discuten resultados obtenidos en el CASLEO y en el Observatorio de Las Campanas de dos cúmulos abiertos compactos con apariencia globular: Westerlund1 (BH197), ubicado en dirección hacia el centro galáctico, y Westerlund2. A partir de espectroscopía CCD integrada de ambos e imágenes CCD en las bandas VI obtenidas para el primero de ellos, se derivan sus parámetros fundamentales y se examinan sus apariencias estructurales. Se encuentra que Westerlund1 es un cúmulo joven (7 ± 3 millones de años), ubicado sobre el plano galáctico a 1.0 ± 0.4 kpc del sol, en una región caracterizada por una absorción excepcionalmente elevada (Av~=13.0 mag), en tanto que Westerlund2 es también un cúmulo joven (4-6 millones de años) ubicado sobre el plano, en una región afectada por una absorción menor (Av~=5.7 mag). Desde el punto de vista estructural, Westerlund 1 se presenta como uno de los pocos cúmulos abiertos jóvenes de la Galaxia con apariencia tipicamente globular, en contraste con los cúmulos azules de las Nubes de Magallanes en los cuales la apariencia globular constituye un fenómeno común. Westerlund2, aunque menos rico en estrellas, puede también ser incluído dentro de esta interesante clase de objetos.

  6. Rb-Sr and Sm-Nd whole rock analyses of basalts of the Grao Para Group, Serra dos Carajas, Brazil

    SciTech Connect

    Olszewski, W.J. Jr.; Gibbs, A.K.; Wirth, K.R.

    1985-01-01

    The Grao Para Group at Serra dos Carajas in the Guapore Shield of Brazil is a 6 km thick sequence of bimodal metavolcanic rock with interbedded iron formations. Rhyolites are a minor part of the low grade meta-volcanic section, with the bulk consisting of subalkaline basalt, basaltic andesite, and shoshonite. Rb-Sr whole rock analyses of 7 basalts yield an age of 2687 +/- 54 Ma. This agrees well with an age of 2758 +/- 39 Ma from zircon U-Pb analyses of the interbedded rhyolites. Except for the allocthonous Imataca Complex of Venezuela, these dates for the Grao Para Group are the first well-constrained Archean ages from the Amazonian Craton. An even older age for the basement to the Grao Para Group is also implied. Sm-Nd whole-rock analyses of four of these basalts did not yield an isochron because of the limited range of /sup 147/Sm//sup 144/Nd values, but element of/sub Nd/ values relative to CHUR were calculated using the Rb-Sr age. The typical LREE-enrichment, lack of Ce depletion or spilitic alteration of alkalies, and the high Sr initial ratios, may indicate that these isotopic patterns were derived by incorporation of some older continental crust in the mafic melts. These data together with an element of/sub Sr/ of +63.6 might indicate significant seawater exchange with volcanic rocks derived from mantle with chondritic REE patterns. This demonstrates the presence of significant continental crust in the Archean and seawater-volcanic rock interaction in a rifting environment similar to modern analogs.

  7. SU-E-T-115: Analysis of Patient Specific QA for VMAT by Disease Site and Planning-Delivery System Using the ScandiDos Delta4 Phantom

    SciTech Connect

    Giaddui, T; Hardin, M; Keller, J; Kremmel, E; Peng, C; Doyle, L; Yu, Y; Xiao, Y; Harrison, A; Fu, M

    2015-06-15

    Purpose: To evaluate patient specific quality assurance (PSQA) for the delivery of volumetric modulated arc therapy (VMAT) by disease site. To compare planning-delivery system (PDS) PSQA pass rates in a dual vendor institution. Methods: PSQA is performed for VMAT plans using a ScandiDos Delta4 phantom. Verification plans are calculated using Varian Eclipse and Elekta Monaco treatment planning systems (TPS) for patients treated using Varian Truebeam and Elekta linear accelerators respectively. Individual arcs are delivered to the Delta4 phantoms and assessed using the gamma index pass criterion(3% Dose Deviation(DD%), 3mm Distance to Agreement(DTA),10% dose threshold and 90% gamma index). Results: A total of 287 VMAT plans and 680 arcs were analyzed. The passing rates for VMAT QA plans were 95% and 98% for head/neck and pelvis/prostate plans respectively, and 100% for chest/abdomen, spine, lung Stereotactic Body Radiotherapy (SBRT) and Stereotactic Radiosurgery(SRS) plans. Average gamma indices were: (99 ± 2) % for pelvis/prostate, chest/abdomen and lung SBRT plans, (97 ± 4) % for head and neck plans and (98 ± 3) % for spine plans. The average DD% and DTA pass rates ranged from 82% to 90% and 98% to 99% respectively for plans in different disease sites. Paired t-test analysis (two tails) indicated no significant differences in the gamma indices between plans delivered using different PDS; the P values were: 0.08, 0.45, and 0.94 for lung SBRT, head/neck and pelvis/prostate plans respectively. The statistical power for comparing PDS in different disease sites with an alpha of 0.05 is 1. Conclusion: The Gamma indices based on 3% DD%, 3 mm DTA and 10% dose threshold for the VMAT QA plans in all disease sites were well above 90%, suggesting the possibility of using a more stringent PSQA criterion. No significant differences were observed in the QA of VMAT plans delivered using different PDS.

  8. Stratigraphy of fluvial sediment sequences and their palaeoenvironmental information in the foreland of the Serra dos Órgãos, southeastern Brazil

    NASA Astrophysics Data System (ADS)

    Kirchner, André; Nehren, Udo; Heinrich, Jürgen

    2013-04-01

    In the hinterland of Rio de Janeiro city the rivers Guapiaçu, Macacu and Iconha originate in the Serra dos Órgãos mountain range and drain into the Atlantic Ocean. Since their channelization in the 1950s, higher flow velocities caused an incision of the rivers into the valley fills. These circumstances provide the possibility to study the alluvial deposits along the streams during low water level and allow conclusions on palaeoenvironmental change and landscape history. Sedimentological investigations of 13 exposures as well as AMS 14C measurements were carried out to investigate sediment properties and reconstruct the sedimentation history within the floodplains. These results enable to distinguish three different facies units. A late Pleistocene Unit I can be detected at the base of the observed exposures and consists of clast-supported fine to coarse gravels. It can be assumed that the gravel bodies were formed by a climatically induced erosional-depositional cycle within a braided river system. The gravels are overlaid by Unit II, a grayish to bluish loam mainly of mid-Holocene age. During generally drier climates these loams have been deposited during high water stages or flooding events as a splay facies proximal to the rivers. A reduced flow competence and relatively stable morphodynamic conditions are assumed for that period. Unit III accumulated in the late Holocene typically consists of several meters of planar or cross bedded sands to fine gravels, interfingered by loamy inclusions, buried peat bogs and organic debris. Fining-upward sequences can be frequently studied within Unit III which were completed by loamy sediments in the uppermost parts of the exposures. The increased flow competence from Unit II to Unit III seems to be a fluvial response to the increased humidity of the late Holocene as well as the enhancement of El Niño-Southern Oscillation (ENSO). Heavy rainfall likely caused higher sediment supply from the steep slopes as well as a

  9. The Serra Pelada Au-PGE deposit, Serra dos Carajás (Pará State, Brazil): geological and geochemical indications for a composite mineralising process

    NASA Astrophysics Data System (ADS)

    Moroni, Marilena; Girardi, Vicente A.; Ferrario, Alfredo

    2001-12-01

    The Serra Pelada Au-PGE-rich deposit is located in the Serra dos Carajás, a leading mining area in Brazil. This region is characterised by a complex geological and structural framework and is affected by deep lateritisation which has lasted for more than 70 Ma. The Serra Pelada deposit is emplaced in a late-Archean low-grade metasedimentary sequence (Rio Fresco/Águas Claras Formation) which is host to other gold deposits in the region (Igarapé Bahia, Águas Claras). The Rio Fresco/Águas Claras sequence was deposited in tectonic basins developed on Archean basement and Au-bearing greenstone terranes which were intruded by PGE-rich layered mafic complexes (e.g. Luanga). The Serra Pelada mineralisation is located along a regional, complex system of strike-slip faults (Cinzento-Carajás systems) which were active during the late Archean to early Proterozoic. The mineralisation appears to be concentrated along a faulted hinge zone of a fold. Ore zone rock facies are dominated by low-grade ferruginous to carbonaceous metasiltstones and minor sandstones, locally brecciated and cemented by quartz (±sulphide) stockwork. Supergene alteration led to partial to total transformation into friable aggregates of kaolinite, Fe oxide-hydroxides, silica and secondary phosphate-sulphates even at depths exceeding 200 m. Precious metals are exceptionally enriched, with up to more than 1,000 ppm Au+PGE in some peculiar ferruginous-graphitic zones locally called "hidrotermalito". Geochemistry shows complex patterns of major and trace elements, particularly rare-earth elements (REE), in mineralised vs. nonmineralised samples. These patterns are interpreted in terms of variable degree of superposition of hydrothermal and supergene alteration. Precious metals show progressive increase from samples with hydrothermal imprint to samples with supergene imprint. The geological evolution of the Carajás region and the characteristics of mineralisation at Serra Pelada may suggest a composite

  10. An interdisciplinary knowledge translation intervention in long-term care: study protocol for the vitamin D and osteoporosis study (ViDOS) pilot cluster randomized controlled trial.

    PubMed

    Kennedy, Courtney C; Ioannidis, George; Giangregorio, Lora M; Adachi, Jonathan D; Thabane, Lehana; Morin, Suzanne N; Crilly, Richard G; Marr, Sharon; Josse, Robert G; Lohfeld, Lynne; Pickard, Laura E; King, Susanne; van der Horst, Mary-Lou; Campbell, Glenda; Stroud, Jackie; Dolovich, Lisa; Sawka, Anna M; Jain, Ravi; Nash, Lynn; Papaioannou, Alexandra

    2012-05-24

    Knowledge translation (KT) research in long-term care (LTC) is still in its early stages. This protocol describes the evaluation of a multifaceted, interdisciplinary KT intervention aimed at integrating evidence-based osteoporosis and fracture prevention strategies into LTC care processes. The Vitamin D and Osteoporosis Study (ViDOS) is underway in 40 LTC homes (n = 19 intervention, n = 21 control) across Ontario, Canada. The primary objectives of this study are to assess the feasibility of delivering the KT intervention, and clinically, to increase the percent of LTC residents prescribed ≥800 IU of vitamin D daily. Eligibility criteria are LTC homes that are serviced by our partner pharmacy provider and have more than one prescribing physician. The target audience within each LTC home is the Professional Advisory Committee (PAC), an interdisciplinary team who meets quarterly. The key elements of the intervention are three interactive educational sessions led by an expert opinion leader, action planning using a quality improvement cycle, audit and feedback reports, nominated internal champions, and reminders/point-of-care tools. Control homes do not receive any intervention, however both intervention and control homes received educational materials as part of the Ontario Osteoporosis Strategy. Primary outcomes are feasibility measures (recruitment, retention, attendance at educational sessions, action plan items identified and initiated, internal champions identified, performance reports provided and reviewed), and vitamin D (≥800 IU/daily) prescribing at 6 and 12 months. Secondary outcomes include the proportion of residents prescribed calcium supplements and osteoporosis medications, and falls and fractures. Qualitative methods will examine the experience of the LTC team with the KT intervention. Homes are centrally randomized to intervention and control groups in blocks of variable size using a computer generated allocation sequence. Randomization is

  11. PAH effects on meio- and microbial benthic communities strongly depend on bioavailability.

    PubMed

    Lindgren, J Fredrik; Hassellöv, Ida-Maja; Dahllöf, Ingela

    2014-01-01

    The effects of anthropogenic pollutants in dissimilar habitats can vary depending on differences in bioavailability. The factors determining bioavailability are not yet fully understood. This study was performed to evaluate whether analysis of total PAH concentrations in sediments is a satisfactory measurement to indicate environmental effects or if bioavailability is needed to be taken into account. We have here performed a 60-day experiment, where nominal PAH concentrations of 1,300 μg/kg sediment were added to three different marine sediments. Meiofaunal and microbial communities were analyzed for alterations in community response at 30 and 60 days. Results showed that bioavailability of PAHs varied between the three different sediments. Nonetheless, the petroleum addition gave rise to significant negative effects on all three sediments at both time points. The two direct measurements of toxicity on the microbial community, potential nitrification and denitrification, displayed a lower effect of the PAH addition in the muddy sediment at both time points, compared to the other two sediment types. No effects were seen in the analysis of meiofaunal community structure. Measurements of PAH bioavailability in the three sediment types concurred with the results from the microbial community, revealing a lower bioavailability in the muddy sediment compared to the other two sediment types, 34% compared to sandy and 18% compared to organic at day 0. At day 60 it was 61% lower compared to sandy and 20% lower compared to organic. The negative effects of the PAH addition on the microbial nitrogen cycle were in six out of eight cases best correlated to the amount of alkylated bioavailable PAH in the sediments, and thus microbial nitrogen cycle is a possible good indicator for assessing PAH-induced stress. The results presented here have implications for risk analysis studies of petroleum-contaminated marine sediments; consequently, sediment characteristics and its effects on bioavailability are important to include. In addition, these results add to the understanding that bioavailability measurements of PAHs are a more correct assessment compared to measurements of total PAH concentrations, and need to be included when estimating effects of PAHs in marine benthic communities.

  12. Geochemistry and petrogenesis of the Mesoarchean granites from the Canaã dos Carajás area, Carajás Province, Brazil: Implications for the origin of Archean granites

    NASA Astrophysics Data System (ADS)

    Feio, G. R. L.; Dall'Agnol, R.

    2012-12-01

    Four Mesoarchean (2.93 to 2.83 Ga) granite units, which encompass the Canaã dos Carajás, Bom Jesus, Cruzadão and Serra Dourada granites, were recognized in the Canaã dos Carajás area of the Archean Carajás Province. The Mesoarchean units are composed dominantly of biotite leucomonzogranites. They are compared with the Neoarchean Planalto suite (2.73 Ga) which encompasses biotite-hornblende monzogranites to syenogranites. The Canaã dos Carajás, Bom Jesus and the variety of the Cruzadão granite with higher (La/Yb)N are geochemically more akin to the calc-alkaline granites, whereas the other varieties of the Cruzadão granite are transitional between calc-alkaline and alkaline granites. The Serra Dourada granite has an ambiguous geochemical character with some features similar to those of calc-alkaline granites and other peraluminous granites. The Planalto granites have ferroan character, are similar geochemically to reduced A-type granites and show a strong geochemical contrast with the Mesoarchean studied granites. The Mesoarchean granites described in the Canaã dos Carajás area are geochemically distinct to those of the Rio Maria domain of the Carajás Province. The Canaã dos Carajás and Bom Jesus granites are similar to the high-Ca granites, whereas the Cruzadão and Serra Dourada are more akin to the low-CaO granites of the Yilgarn craton. The geochemical characteristics of the Mesoarchean studied granites approach those of the biotite granite group of Dharwar but the latter are enriched in HFSE and HREE compared to the Canaã dos Carajás granites. The Neoarchean Planalto suite granite has no counterpart in the Mesoarchean Rio Maria domain of the Carajás Province, neither in the Yilgarn and Dharwar cratons. Geochemical modeling suggests that partial melting of a source similar in composition to an Archean basaltic andesite of the Carajás Province could give origin to the Bom Jesus and Cruzadão granites. In the case of the Bom Jesus granite the

  13. Determinação de elementos próprios dos asteróides troianos: comparação entre as teorias semi-analítica e sintética

    NASA Astrophysics Data System (ADS)

    Roig, F.; Beaugé, C.

    2003-08-01

    Além do cálculo semi-analítico de elementos próprios dos asteróides Troianos (Beaugé & Roig 2001, Icarus 153, 391), recentemente foi apresentado um novo conjunto destes elementos próprios determinado através de uma teoria sintética (Knenezevic & Milani 2003, comunicação pessoal). As bases de dados contendo estas determinações estão disponiveis na pagina web do Asteroid Dynamical Site (http://hamilton.dm.unipi.it/cgi-bin/astdys/astibo). Nesta comunicação apresentamos os primeiros resultados de um estudo comparativo entre ambos conjuntos de elementos próprios, analisando suas vantagens e desvantagens, assim como os limites de precisão de cada conjunto. Mostramos que os elementos próprios sintéticos são mais precisos que os smi-analíticos para grandes amplitudes de libração do ângulo s = l-lJup, embora acontece o contrario para os corpos cuja amplitude de libração é muito pequena. Finalmente discutimos a influencia destes erros na determinação de familias de asteroides e da estrutura resonante em torno dos pontos Lagrangeanos L4 e L5.

  14. Child Development: New Diagnoses for the NANDA International.

    PubMed

    Souza, Juliana Martins de; Cruz, Diná de Almeida Lopes Monteiro da; Veríssimo, Maria De La Ó Ramallo

    2016-12-15

    The paper proposes new diagnoses on child development (CD) for NANDA International. The study followed the recommended steps of Developmental Processes for NANDA International Nursing Diagnoses. It was a secondary analysis study on the findings of a concept analysis study on CD. A proposal of labels and components of three diagnoses: "Delayed child development," "Risk for delayed child development," and "Readiness for enhanced child development." The proposed diagnoses represent all the complexity of CD. The proposed diagnoses can support nurses in the development of a comprehensive care plan on the health of children. OBJETIVO: propor novos diagnósticos de enfermagem para a NANDA-International que abordem o desenvolvimento infantil. MÉTODO: Este estudo seguiu as etapas recomendadas para o desenvolvimento de diagnósticos de enfermagem da NANDA-International. Foi realizado a partir dos resultados da análise de conceito do termo desenvolvimento infantil. Propostos os títulos e os componentes de três diagnósticos: "Atraso no desenvolvimento infantil," "Risco de atraso no desenvolvimento infantil," e "Disposição para desenvolvimento infantil melhorado." CONCLUSÕES: Os diagnósticos propostos contemplam toda a complexidade do desenvolvimento infantil. IMPLICAÇÕES PARA A PRÁTICA DE ENFERMAGEM: Os novos diagnósticos podem subsidiar o enfermeiro na elaboração de um plano de cuidados integrais à saúde da criança. © 2016 NANDA International, Inc.

  15. Factores socio-económicos asociados a la percepción de situación socioeconómica entre adultos mayores de dos países latinoamericanos

    PubMed Central

    Brenes-Camacho, Gilbert

    2014-01-01

    El objetivo principal del artículo es estudiar la asociación entre la percepción subjetiva sobre la situación económica propia y una serie de medidas objetivas de bienestar socioeconómico –fuentes de ingresos, tenencia de vivienda, nivel educativo y transferencias familiares informales de dinero- entre adultos mayores de dos países Latinoamericanos: México y Costa Rica. Los datos se obtienen de las primeras rondas de dos encuestas sobre envejecimiento: CRELES para Costa Rica y ENASEM para México. La variable dependiente más importante se obtiene de las respuestas a las pregunta “¿Cómo califica su situación económica actual?” en Costa Rica y “¿Diría usted que su situación económica es…?” en México. Para ambas encuestas, las respuestas se codificaron en forma binaria; el código 0 representa las categorías Excelente, Muy buena y Buena, y el código 1 representa a las categorías Regular y Mala. Se encontró que el ingreso por jubilación es un importante determinante de la percepción de bienestar en ambos países. En Costa Rica, el ingreso del cónyuge y la tenencia de vivienda son importantes predictores de la percepción de bienestar, mientras que en México, los ingresos por transferencias están fuertemente asociados con dicha percepción. PMID:25360057

  16. Identificabilidade e estabilidade dos parâmetros no método Grade of Membership (GoM): considerações metodológicas e práticas

    PubMed Central

    Guedes, Gilvan Ramalho; Caetano, André Junqueira; Machado, Carla Jorge; Brondízio, Eduardo Sonewend

    2011-01-01

    O método Grade of Membership (GoM) tem sido cada vez mais utilizado por demógrafos brasileiros e tem a vantagem de possuir um parâmetro que mensura a heterogeneidade individual, com base nas correlações não-observáveis entre as categorias de resposta das variáveis de interesse, gerando um medida do grau de pertencimento de cada indivíduo a perfis extremos. Alguns autores, contudo, chamam atenção para questões importantes na calibragem dos modelos finais que utilizam o programa GoM versão 3.4, como o problema de identificabilidade – soluções múltiplas para parâmetros estimados. Neste artigo, é sugerido um procedimento capaz de identificar um modelo final com solução única que descreva os tipos puros mais fidedignos à base de dados, em uma tentativa de otimização. Para ilustrar esse processo, utilizou-se uma base de dados correspondente a um levantamento econômico e sociodemográfico de uma população de pequenos agricultores residentes ao longo da Rodovia Transamazônica, no Estado do Pará. Também identificou-se a existência de instabilidade nos parâmetros estimados pelo programa GoM 3.4, sendo proposto um método de estabilização de seus valores. Com esses procedimentos combinados, os usuários do programa GoM 3.4 poderão descrever sua base de dados de forma mais adequada e responder às críticas sobre questões de identificabilidade e estabilidade dos modelos resultantes. Essas soluções empíricas são relevantes por afetarem cálculos de prevalência e de incidência de eventos de interesse, além de trazerem consequências importantes sobre o ponto e o momento corretos para intervenções de políticas públicas ou de planejamento prospectivo em análises de projeção. PMID:21709732

  17. Tritium ((3)H) as a tracer for monitoring the dispersion of conservative radionuclides discharged by the Angra dos Reis nuclear power plants in the Piraquara de Fora Bay, Brazil.

    PubMed

    de Carvalho Gomes, Franciane; Godoy, José Marcus; de Carvalho, Zenildo Lara; de Souza, Elder Magalhães; Rodrigues Silva, José Ivan; Tadeu Lopes, Ricardo

    2014-10-01

    Presently, two nuclear power plants operate in Brazil. Both are located at Itaorna beach, Angra dos Reis, approximately 133 km from Rio de Janeiro city. The reactor cooling circuits require the input of seawater, which is later discharged through a pipeline into the adjacent Piraquara de Fora Cove. The radioactive effluents undergo ion-exchange treatment prior to their release in batches, causing the enrichment of (3)H relative to other radionuclides in the discharged waters. Under steady state conditions, the (3)H gradient in the Piraquara de Fora waters can be used to determine the dependence of the dilution factor on the distance from the discharge point. The present work describes experiments carried out at the reactor site during batch release episodes, including time series sampling at the discharge point and surface seawater sampling every 250 m to a distance of 1250 m, after a double distillation, the (3)H concentration was measured by liquid scintillation counting applying a Quantulus liquid scintillation spectrometer. The obtained results showed a linear relationship between the (3)H concentration and distance from the discharge point. At 1250 m from the discharge point a dilution index of 1:15 was measured which fits the expected value based on modeling.

  18. Automatic scaling of critical frequency foF2 from ionograms recorded at São José dos Campos, Brazil: a comparison between Autoscala and UDIDA tools

    NASA Astrophysics Data System (ADS)

    Pezzopane, Michael; Pillat, Valdir Gil; Fagundes, Paulo Roberto

    2017-02-01

    This paper considers a dataset of ionograms recorded by the CADI ionosonde installed at São José dos Campos (SJC; 23.2°S, 45.9°W, magnetic latitude 14.1°S), Brazil, to compare two autoscaling systems: Autoscala, developed by the Istituto Nazionale di Geofisica e Vulcanologia, and the UDIDA-scaling, developed by the Universidade do Vale do Paraíba. The analysis, focused on the critical frequency of the F2 layer, foF2, shows that the two systems work differently. The UDIDA-scaling gives always a value of foF2 as output, regardless of the presence of the ionogram trace and its definition, while Autoscala tends to reject ionograms for which the digital information is considered insufficient. As a consequence, the UDIDA-scaling can autoscale more foF2 values than Autoscala, but Autoscala can discard a larger number of ionograms for which the trace is unidentifiable. Discussions are made on the accuracy of the foF2 values given as output, as well as on the main shortcomings characterizing the two systems.

  19. Pepita Talks Twice = Pepita habla dos veces.

    ERIC Educational Resources Information Center

    Lachtman, Ofelia Dumas

    This illustrated bilingual children's book (English and Spanish), relates the story of Pepita, a young Hispanic girl who is fluent in both Spanish and English. Pepita always helps when asked to talk for others in Spanish and English. But one day Pepita decides she doesn't want to help anymore. She wants to hurry and get home from school before her…

  20. 27 CFR 9.175 - Dos Rios.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... contour line and Poonkinny Road, proceed southerly and then easterly along the meandering 2,000-foot contour line to its intersection with the eastern boundary of section 2, T21N, R13W, immediately south of... then westerly along the meandering 2,000-foot contour line, crossing Big Water Canyon, Doghouse...

  1. 27 CFR 9.175 - Dos Rios.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... contour line and Poonkinny Road, proceed southerly and then easterly along the meandering 2,000-foot contour line to its intersection with the eastern boundary of section 2, T21N, R13W, immediately south of... then westerly along the meandering 2,000-foot contour line, crossing Big Water Canyon, Doghouse...

  2. 27 CFR 9.175 - Dos Rios.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... contour line and Poonkinny Road, proceed southerly and then easterly along the meandering 2,000-foot contour line to its intersection with the eastern boundary of section 2, T21N, R13W, immediately south of... then westerly along the meandering 2,000-foot contour line, crossing Big Water Canyon, Doghouse...

  3. 27 CFR 9.175 - Dos Rios.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... contour line and Poonkinny Road, proceed southerly and then easterly along the meandering 2,000-foot contour line to its intersection with the eastern boundary of section 2, T21N, R13W, immediately south of... then westerly along the meandering 2,000-foot contour line, crossing Big Water Canyon, Doghouse...

  4. DOS/Russian - US program overview

    SciTech Connect

    Pifer, M.L.

    1996-04-01

    This paper describes the organization and describes the objectives for the science and technology agreements between the U.S.A. and Russia. The Gore-Chernomyrdin Commission objectives and the Civilian Research and the Development Foundation for the Independent States of the former Soviet Union (CRDF) are discussed.

  5. DOS Design/Application Tools. Volume 1

    DTIC Science & Technology

    1990-09-01

    a distributed program must be partitioned into a number of program units (objects and clients ) and subsequently allocated to the various processors...initiates the appropriate processes (objects and clients ) on the designated nodes. Payoff for Developers Performance: The allocation tool directly addresses...the relationship between a particular Unit of Distribution and the Processor to which it has been assigned for execution. Finally, note that Client (a

  6. Pepita Talks Twice = Pepita habla dos veces.

    ERIC Educational Resources Information Center

    Lachtman, Ofelia Dumas

    This illustrated bilingual children's book (English and Spanish), relates the story of Pepita, a young Hispanic girl who is fluent in both Spanish and English. Pepita always helps when asked to talk for others in Spanish and English. But one day Pepita decides she doesn't want to help anymore. She wants to hurry and get home from school before her…

  7. DIGLIB. PC-DOS Graphics Subroutine Library

    SciTech Connect

    Brand, H.R.

    1989-02-01

    DIGLIB is a collection of general graphics subroutines. It was designed to be small, reasonably fast, and device-independent. The software is readily usable by casual programmers for two-dimensional plotting.

  8. Molecular Characterization of Human Pathogenic Bunyaviruses of the Nyando and Bwamba/Pongola Virus Groups Leads to the Genetic Identification of Mojuí dos Campos and Kaeng Khoi Virus

    PubMed Central

    Groseth, Allison; Mampilli, Veena; Weisend, Carla; Dahlstrom, Eric; Porcella, Stephen F.; Russell, Brandy J.; Tesh, Robert B.; Ebihara, Hideki

    2014-01-01

    Background Human infection with Bwamba virus (BWAV) and the closely related Pongola virus (PGAV), as well as Nyando virus (NDV), are important causes of febrile illness in Africa. However, despite seroprevalence studies that indicate high rates of infection in many countries, these viruses remain relatively unknown and unstudied. In addition, a number of unclassified bunyaviruses have been isolated over the years often with uncertain relationships to human disease. Methodology/Principal Findings In order to better understand the genetic and evolutionary relationships among orthobunyaviruses associated with human disease, we have sequenced the complete genomes for all 3 segments of multiple strains of BWAV (n = 2), PGAV (n = 2) and NDV (n = 4), as well as the previously unclassified Mojuí dos Campos (MDCV) and Kaeng Khoi viruses (KKV). Based on phylogenetic analysis, we show that these viruses populate 2 distinct branches, one made up of BWAV and PGAV and the other composed of NDV, MDCV and KKV. Interestingly, the NDV strains analyzed form two distinct clades which differed by >10% on the amino acid level across all protein products. In addition, the assignment of two bat-associated bunyaviruses into the NDV group, which is clearly associated with mosquito-borne infection, led us to analyze the ability of these different viruses to grow in bat (RE05 and Tb 1 Lu) and mosquito (C6/36) cell lines, and indeed all the viruses tested were capable of efficient growth in these cell types. Conclusions/Significance On the basis of our analyses, it is proposed to reclassify the NDV strains ERET147 and YM176-66 as a new virus species. Further, our analysis definitively identifies the previously unclassified bunyaviruses MDCV and KKV as distinct species within the NDV group and suggests that these viruses may have a broader host range than is currently appreciated. PMID:25188437

  9. Impact of natural climate change and historical land use on vegetation cover and geomorphological process dynamics in the Serra dos Órgãos mountain range in Rio de Janeiro State, Brazil

    NASA Astrophysics Data System (ADS)

    Nehren, U.; Sattler, D.; Heinrich, J.

    2010-03-01

    The Serra dos Órgãos mountain range in the hinterland of Rio de Janeiro contains extensive remnants of the Atlantic Forest (Mata Atlântica) biome, which once covered about 1.5 million km² from Northeast to South Brazil and further inland to Paraguay and Argentina. As a result of historical deforestation and recent land use intensification processes today only 5 to 8% of the original Atlantic Forest remains. Despite the dramatic habitat loss and a high degree of forest fragmentation, the remnants are among the Earth’s most diverse habitats in terms of species richness. Furthermore, they are characterized by a high level of endemism. Therefore, the biome is considered a "hotspot of biodiversity". In the last years many efforts have been taken to investigate the Mata Atlântica biome in different spatial and time scales and from different scientific perspectives. We are working in the Atlantic Forest of Rio de Janeiro since 2004 and focus in our research particularly on Quaternary landscape evolution and landscape history. By means of landscape and soil archives we reconstruct changes in the landscape system, which are mainly the result of Quaternary climate variability, young tectonic uplift and human impact. The findings throw light on paleoecological conditions in the Late Quaternary and the impact of pre-colonial and colonial land use practices on these landscapes. In this context, a main focus is set on climate and human-driven changes of the vegetation cover and its consequences for the geomorphological process dynamics, in particular erosion and sedimentation processes. Research methods include geomorphological field studies, interpretation of satellite images, physical and chemical sediment and soil analyses as well as relative and absolute dating (Feo/Fed ratio and 14C dating). For the Late Quaternary landscape evolution, the findings are compared with results from paleoclimatic and paloecological investigations in Southeast and South Brazil using other

  10. ASSESSMENT FORM - NEW IMPROVEMENT OF ACTIONS: CONCENTRATION AND RESEARCH AREAS / CURRICULUM STRUCTURE / FUNDRAISING.

    PubMed

    Calderon, Iracema Mp

    2015-01-01

    AC, LP e PP, com substancial vínculo entre atividades e competências do corpo de docentes permanentes e embasamento da grade curricular na formação do aluno. A Proposta do Programa interfere, e muito, na qualificação de um programa. A estrutura curricular deverá dar subsídio à formação do pesquisador, por meio das disciplinas nucleares, e ao desenvolvimento dos PP, de competência das disciplinas de apoio às linhas e aos projetos de pesquisa. Os fomentos devem ser indicados nos projetos de pesquisa e no CV-Lattes dos beneficiados/responsáveis pelos projetos. A área recomenda que, no mínimo, 40 a 50% dos docentes permanentes apresentem captação de recursos e que o mínimo de 20 a 25% desses docentes tenham bolsa de produtividade PQ/CNPq durante o triênio. Há que se promover ampla discussão e encontrar um denominador de consenso para essas questões. As ações deverão contribuir para o aprimoramento das fichas de avaliação e, certamente, para a qualificação dos programas de pós-graduação.

  11. Gestational Protein Restriction Increases Cardiac Connexin 43 mRNA levels in male adult rat offspring.

    PubMed

    Rossini, Kamila Fernanda; Oliveira, Camila Andrea de; Rebelato, Hércules Jonas; Esquisatto, Marcelo Augusto Marreto; Catisti, Rosana

    2017-07-01

    The dietary limitation during pregnancy influences the growth and development of the fetus and offspring and their health into adult life. The mechanisms underlying the adverse effects of gestational protein restriction (GPR) in the development of the offspring hearts are not well understood. The aim of this study was to evaluate the effects of GPR on cardiac structure in male rat offspring at day 60 after birth (d60). Pregnant Wistar rats were fed a normal-protein (NP, 17% casein) or low-protein (LP, 6% casein) diet. Blood pressure (BP) values from 60-day-old male offspring were measured by an indirect tail-cuff method using an electro sphygmomanometer. Hearts (d60) were collected for assessment of connexin 43 (Cx43) mRNA expression and morphological and morphometric analysis. LP offspring showed no difference in body weight, although they were born lighter than NP offspring. BP levels were significantly higher in the LP group. We observed a significant increase in the area occupied by collagen fibers, a decrease in the number of cardiomyocytes by 104 µm2, and an increase in cardiomyocyte area associated with an increased Cx43 expression. GPR changes myocardial levels of Cx43 mRNA in male young adult rats, suggesting that this mechanism aims to compensate the fibrotic process by the accumulation of collagen fibers in the heart interstitium. A limitação dietética durante a gravidez influencia o crescimento e desenvolvimento do feto e da prole e sua saúde na vida adulta. Os mecanismos subjacentes dos efeitos adversos da restrição proteica gestacional (RPG) no desenvolvimento dos corações da prole não são bem compreendidos. Avaliar os efeitos da RPG sobre a estrutura cardíaca em filhotes machos de ratas aos 60 dias após o nascimento (d60). Ratos fêmeas Wistar grávidas foram alimentadas com uma dieta de proteína normal (PN, 17% caseína) ou de baixa proteína (BP, caseína 6%). Os valores de pressão arterial (PA) de descendentes do sexo masculino de

  12. ANÁLISE DA INSERÇÃO DOS TEMAS DE HUMANIDADES E ÉTICA, COM METODOLOGIA DE APRENDIZAGEM BASEADA EM PROBLEMAS, EM CURRICULO MÉDICO INTEGRADO EM ESCOLA PÚBLICA NO DISTRITO FEDERAL, BRASIL

    PubMed Central

    Novaes, Maria Rita Carvalho Garbi; Novaes, Luiz Carlos Garcez; Guilhem, Dirce; Lolas, Fernando; Silveira, Carla; Guiotti, Murilo

    2009-01-01

    Objetivo Realizar uma análise da inserção da ética e humanidades no currículo do Curso de Medicina da Escola Superior em Ciências da Saúde - ESCS, escola pública do Distrito Federal, Brasil, de forma a contribuir com o processo de gestão curricular. Metodologia O Estudo é de coorte e documental. Foram pesquisados 37 termos relacionados à ética e 36 referentes à humanização nos objetivos educacionais e conteúdo dos módulos temáticos, habilidades e atitudes e interação ensino-serviço-comunidade, de 1a a 4a série e no programa do internato no currículo (ano 2006) e no projeto pedagógico do Curso de Medicina (2001). Resultados Maior inserção da humanização, ética e bioética na 1a e 2a série, quando comparado à inserção na 3a e 4a série e no internato, (IC95%-α=0,034, pvalue=0,007). Unidade de habilidades e atitudes: freqüência das 3 temáticas no currículo da 1a a 4a séries (IC95%-α=0,026, pvalue=0,013). Quando comparada a inserção entre o internato e as quatro primeiras séries, observa-se que nestas a inserção da temática humanização é superior (IC95%-α=0,042, pvalue=0,029). Conclusão O currículo desenvolvido no ano de 2006 na ESCS apresentou correlação com o projeto pedagógico do curso e contemplou a temática de forma abrangente, em todas as séries e internato. PMID:20396594

  13. Autism spectrum disorders: an updated guide for genetic counseling.

    PubMed

    Griesi-Oliveira, Karina; Sertié, Andréa Laurato

    2017-01-01

    Autism spectrum disorder is a complex and genetically heterogeneous disorder, which has hampered the identification of the etiological factors in each patient and, consequently, the genetic counseling for families at risk. However, in the last decades, the remarkable advances in the knowledge of genetic aspects of autism based on genetic and molecular research, as well as the development of new molecular diagnostic tools, have substantially changed this scenario. Nowadays, it is estimated that using the currently available molecular tests, a potential underlying genetic cause can be identified in nearly 25% of cases. Combined with clinical assessment, prenatal history evaluation and investigation of other physiological aspects, an etiological explanation for the disease can be found for approximately 30 to 40% of patients. Therefore, in view of the current knowledge about the genetic architecture of autism spectrum disorder, which has contributed for a more precise genetic counseling, and of the potential benefits that an etiological investigation can bring to patients and families, molecular genetic investigation has become increasingly important. Here, we discuss the current view of the genetic architecture of autism spectrum disorder, and list the main associated genetic alterations, the available molecular tests and the key aspects for the genetic counseling of these families. RESUMO O transtorno do espectro autista é um distúrbio complexo e geneticamente heterogêneo, o que sempre dificultou a identificação de sua etiologia em cada paciente em particular e, por consequência, o aconselhamento genético das famílias. Porém, nas últimas décadas, o acúmulo crescente de conhecimento oriundo das pesquisas sobre os aspectos genéticos e moleculares desta doença, assim como o desenvolvimento de novas ferramentas de diagnóstico molecular, tem mudado este cenário de forma substancial. Atualmente, estima-se que, por meio de testes moleculares, é poss

  14. Screening for pulmonary tuberculosis in Teresópolis, RJ, Brazil: the search for respiratory symptomatic patients in emergency service of "Hospital das Clínicas de Teresópolis Costantino Ottaviano, Fundação Educacional Serra dos Orgãos".

    PubMed

    Siqueira-Batista, Rodrigo; Gomes, Andréia Patrícia; Bisaglia, Joana B; Borlot, Paulo Estevão W; D'avila Junior, Heraldo X; Faria, Carolina Gonçalves P P de; Braga, Bernardo D; Bezerra, Tiago S; Cedrola, Juan Pedro V; Almeida, Guilherme C; Couto, Lílian S; Nacif, Marcelo; Crivano, Elvira

    2005-01-01

    The aim of the present study was to investigate the detection percentage of tuberculosis among patients that are respiratory symptomatic (TB suspects). In this work, we present the preliminary results of research carried out at "Hospital das Clínicas de Teresópolis Costantino Ottaviano da Fundacao Educacional Serra dos Orgãos (FESO)" from November 2003 to April 2004. Among the 40 respiratory symptomatic individuals identified and referred to the Tuberculosis Control Program in Teresópolis , two (5.0%) were characterized as smear-positive. These results confirm reports in the literature and underscore the need for and importance of this strategy.

  15. Sobre o uso das séries de Puiseux em mecanica celeste

    NASA Astrophysics Data System (ADS)

    Miloni, O. I.

    2003-08-01

    Neste trabalho é apresentada uma demonstração do uso dos diferentes desenvolvimentos em séries para as equações de perturbação em Mecânica Celeste no marco Hamiltoniano. Em trabalhos clássicos como os de Poincaré (Poincaré, 1893) por exemplo, já esta planteado o uso de potências não inteiras no pequeno parâmetro, o que evidencia a não analiticidade das funções quando uma ressonância ocorre. Nestes trabalhos os desenvolvimentos são na raíz quadrada da massa de Júpiter (o pequeno parâmetro). Mais recentemente (Ferraz-Mello, 1985) outros tipos de desenvolvimentos foram aplicados modificando substancialmente as ordens de grandeza e a velocidade de convergência das séries. Com esta abordagem, os desenvolvimentos foram expressados em termos da raíz cúbica do pequeno parâmetro. Neste trabalho apresentamos um enfoque geral, onde os diferentes tipos de desenvolvimentos em séries de Puiseux (Valiron, 1950) são obtidos a partir da aplicação de Teorema de Preparação de Weierstrass (Goursat, 1916) considerando a equação de Hamilton-Jacobi como uma equação algébrica. Os resultados são aplicados ao problema restrito dos três corpos em ressonância de primeira ordem e, dependendo da grandeza da excentricidade do asteróide em relação à de Júpiter, obtemos os diferentes desenvolvimentos, em raíz quadrada ou raíz cúbica da massa de Júpiter.

  16. Network as transconcept: elements for a conceptual demarcation in the field of public health.

    PubMed

    Amaral, Carlos Eduardo Menezes; Bosi, Maria Lúcia Magalhães

    2016-08-22

    The main proposal to set up an articulated mode of operation of health services has been the concept of network, which has been appropriated in different ways in the field of public health, as it is used in other disciplinary fields or even taking it from common sense. Amid the diversity of uses and concepts, we recognize the need for rigorous conceptual demarcation about networks in the field of health. Such concern aims to preserve the strategic potential of this concept in the research and planning in the field, overcoming uncertainties and distortions still observed in its discourse-analytic circulation in public health. To this end, we will introduce the current uses of network in different disciplinary fields, emphasizing dialogues with the field of public health. With this, we intend to stimulate discussions about the development of empirical dimensions and analytical models that may allow us to understand the processes produced within and around health networks. RESUMO A principal proposta para configurar um modo articulado de funcionamento dos serviços de saúde tem sido o conceito de rede, que vem sendo apropriado de diferentes formas no campo da saúde coletiva, conforme seu emprego em outros campos disciplinares ou mesmo tomando-o do senso comum. Em meio à pluralidade de usos e concepções, reconhecemos a necessidade de rigorosa demarcação conceitual acerca de redes no campo da saúde. Tal preocupação visa a preservar o potencial estratégico desse conceito na investigação e planificação no campo, superando precariedades e distorções ainda observadas em sua circulação discursivo-analítica na saúde coletiva. Para tanto, apresentaremos os usos correntes de rede em diferentes campos disciplinares, destacando interlocuções com o campo da saúde coletiva. Com isso, pretendemos estimular o debate acerca do desenvolvimento de dimensões empíricas e modelos de análise que permitam compreender os processos produzidos no interior e ao redor

  17. Meio- and Macrofaunal Communities in Artificial Water-Filled Tree Holes: Effects of Seasonality, Physical and Chemical Parameters, and Availability of Food Resources

    PubMed Central

    Ptatscheck, Christoph; Traunspurger, Walter

    2015-01-01

    Objectives In this study we investigated the dynamics of meiofaunal and macrofaunal communities in artificial water-filled tree holes. The abundances and, for the first time, biomasses and secondary production rates of these communities were examined. The experimental set-up consisted of 300 brown plastic cups placed in temperate mixed forests and sampled five times over a period of 16 months to determine the impact of (i) seasonal events, (ii) physicochemical parameters, and (iii) food resources on the tree hole metazoans. Outcomes Metazoan organisms, especially the meiofauna (rotifers and nematodes) occupied nearly all of the cups (> 99%) throughout the year. Between 55% and 99% of the metazoan community was represented by rotifers (max. 557,000 individuals 100 cm-2) and nematodes (max. 58,000 individuals 100 cm-2). Diptera taxa, particularly Dasyhelea sp. (max. 256 individuals 100 cm-2) dominated the macrofaunal community. Macrofauna accounted for the majority of the metazoan biomass, with a mean dry weight of 5,800 μg 100 cm-2 and an annual production rate of 20,400 μg C 100 cm-2, whereas for meiofauna mean biomass and annual production were 100 μg 100 cm-2 and 5,300 μg C 100 cm-2, respectively. The macrofaunal taxa tended to show more fluctuating population dynamic while the meiofaunal dynamic was rather low with partly asynchronous development. Seasonality (average temperature and rain intervals) had a significant impact on both meiofauna and macrofauna. Furthermore, bottom-up control (chlorophyll-a and organic carbon), mainly attributable to algae, was a significant factor that shaped the metazoan communities. In contrast, physicochemical water parameters had no evident influence. 23.7% of organism density distribution was explained by redundancy analysis (RDA) indicating a high dynamic and asynchrony of the systems. PMID:26284811

  18. Quality of cervical cancer screening in Brazil: external assessment of the PMAQ.

    PubMed

    Barcelos, Mara Rejane Barroso; Lima, Rita de Cássia Duarte; Tomasi, Elaine; Nunes, Bruno Pereira; Duro, Suele Manjourany Silva; Facchini, Luiz Augusto

    2017-07-20

    érito realizado em serviços de saúde das cinco regiões brasileiras em 2012. A amostra foi composta por usuárias de unidades básicas de saúde participantes do Programa de Melhoria do Acesso e da Qualidade na Atenção Básica. As variáveis independentes analisadas foram: características socioeconômicas (contexto municipal); características demográficas (perfil de usuárias); e dois domínios relativos à organização dos serviços básicos (estrutura e processo de trabalho). A baixa qualidade do rastreamento foi avaliada por meio da falta de acesso, atraso na realização do exame e falta de recebimento de orientações. Análises bruta e ajustada por meio de regressão de Poisson avaliaram a associação entre os desfechos e as variáveis independentes. A falta de acesso, atraso na realização do exame e falta de recebimento de orientações foram de 6,7%, 11,2% e 19,2%, respectivamente. Os problemas de qualidade foram menores de acordo com o aumento do Índice de Desenvolvimento Humano Municipal e da renda familiar per capita, aumentando com o porte populacional e a cobertura municipal da Estratégia Saúde da Família. A região Centro-Oeste do país apresentou as maiores ocorrências dos desfechos de baixa qualidade. As mulheres de raça indígena e amarela tiveram as maiores prevalências dos desfechos. As mulheres com companheiro, que recebiam o benefício do Programa Bolsa Família e tinham trabalho remunerado tiveram menos falta de acesso, menos atraso na realização do exame e menos falta de recebimento de orientações. O processo de trabalho adequado nos serviços de saúde diminuiu a probabilidade de baixa qualidade em todos os indicadores. Investimentos em processo de trabalho das equipes de saúde, programas sociais de transferência de renda e condições sociais da população são essenciais para melhorar a qualidade do programa de rastreamento de colo de útero no Brasil.

  19. [Anxiety in clinical settings: constructing a scale for medical students].

    PubMed

    Rodrigues, Joana Ramos; Castelo-Branco, Miguel; Pereira, Henrique; Afonso, Rosa Marina

    2014-01-01

    IntroduçÉo: A Escala de Ansiedade em Meio Clínico foi construída para avaliar o nível de ansiedade dos estudantes de Medicina quando expostos ao meio clínico e identificar quais as situações mais propensas a desencadear maior nível de ansiedade nesse contexto.Material e Métodos: Este instrumento é constituído por doze itens e foi construído tendo por base a revisÉo da literatura sobre a temática da ansiedade em meio clínico e os dados provenientes de um focus group realizado com estudantes entre o 1'º e o 5'º ano do curso de Medicina da Universidade da Beira Interior (n = 10). As suas propriedades psicométricas foram testadas mediante um estudo com 557 alunos do curso de Medicina de quatro universidades portuguesas, entre o 1'º e o 6'º ano.Resultados: A validaçÉo da Escala de Ansiedade em Meio Clínico contemplou a análise de três par'metros principais: sensibilidade, fiabilidade e análise da estrutura fatorial, sendo que a última resultou na obtençÉo de quatro factores: 'Incómodo perante procedimentos invasivos', 'Ansiedade face ao doente', 'Ansiedade face ao desempenho' e 'Ansiedade face à dimensÉo humana' com 70,6% da vari'ncia explicada.DiscussÉo: A Escala de Ansiedade em Meio Clínico total demonstra uma boa coerência interna (Alpha de Cronbach = 0,84) e boa capacidade de discriminaçÉo de sujeitos, apresentando-se, assim, como instrumento consistente e fiável para a avaliaçÉo de ansiedade nos estudantes de Medicina quando expostos ao meio clínico.ConclusÉo: A Escala de Ansiedade em Meio Clínico permite avaliar a ansiedade nos estudantes de Medicina quando expostos ao meio clínico e poderá vir a ser útil na delineaçÉo de estratégias de ensino para a preparaçÉo dos futuros médicos.

  20. Exercise beyond menopause: Dos and Don’ts

    PubMed Central

    Mishra, Nalini; Mishra, V. N.; Devanshi

    2011-01-01

    With a significant number of women belonging to the status of menopause and beyond, it is imperative to plan a comprehensive health program for them, including lifestyle modifications. Exercise is an integral part of the strategy. The benefits are many, most important being maintenance of muscle mass and thereby the bone mass and strength. The exercise program for postmenopausal women should include the endurance exercise (aerobic), strength exercise and balance exercise; it should aim for two hours and 30 minutes of moderate aerobic activity each week. Every woman should be aware of her target heart rate range and should track the intensity of exercise employing the talk test. Other deep breathing, yoga and stretching exercises can help to manage the stress of life and menopause-related symptoms. Exercises for women with osteoporosis should not include high impact aerobics or activities in which a fall is likely. The women and the treating medical practitioner should also be aware of the warning symptoms and contraindications regarding exercise prescription in women beyond menopause. The role of exercise in hot flashes, however, remains inconclusive. Overall, exercising beyond menopause is the only noncontroversial and beneficial aspect of lifestyle modification and must be opted by all. PMID:22408332

  1. Face mask ventilation--the dos and don'ts.

    PubMed

    Wood, Fiona E; Morley, Colin J

    2013-12-01

    Face mask ventilation provides respiratory support to newly born or sick infants. It is a challenging technique and difficult to ensure that an appropriate tidal volume is delivered because large and variable leaks occur between the mask and face; airway obstruction may also occur. Technique is more important than the mask shape although the size must appropriately fit the face. The essence of the technique is to roll the mask on to the face from the chin while avoiding the eyes, with a finger and thumb apply a strong even downward pressure to the top of the mask, away from the stem and sloped sides or skirt of the mask, place the other fingers under the jaw and apply a similar upward pressure. Preterm infants require continuous end-expiratory pressure to facilitate lung aeration and maintain lung volume. This is best done with a T-piece device, not a self-inflating or flow-inflating bag. Copyright © 2013 Elsevier Ltd. All rights reserved.

  2. ORAMUS(DOS). Ozone Risk AssessMent Utilities

    SciTech Connect

    Whitfield, R.G.; Jusko, M.J.; Biller, W.F.

    1998-12-01

    ORAMUS is a user-friendly, menu-driven software system that calculates and displays user-selected risk estimates for health effects attributable to short-term exposure to tropospheric ozone. Inputs to the risk assessment are estimates of exposure to ozone and exposure-response relationships to produce overall risk estimates in the form of probability distributions. Three fundamental models are included: headcount risk, benchmark risk, and hospital admissions. Exposure-response relationships are based on results of controlled human exposure studies. Exposure estimates are based on the EPA`s probabilistic national ambient air quality standards (NAAQS) exposure model, pNEM/Osub3, which simulates air quality associated with attainment of alternative NAAQS. Using ORAMUS, risk results for 27 air quality scenarios, air quality in 9 urban areas, 33 acute health endpoints, and 4 chronic health endpoints can be calculated.

  3. Los Dos Mundos: Rural Mexican Americans, Another America.

    ERIC Educational Resources Information Center

    Baker, Richard

    This book explores race relations between Mexican Americans and Anglo Americans in "Middlewest," a fictitious name for an actual rural Idaho community with the highest proportion of Mexican Americans in the state. Many Mexican Americans in this predominantly agricultural area are current or former migrant workers. The first chapter…

  4. Dos and Don'ts for a Fabulous Pedicure

    MedlinePlus

    ... stick under your nails. This helps keep your nails clean and removes the dirt, glitter, and other types of build-up you may not be able to see. Do bring your own pedicure utensils to the salon. Why? Because bacteria and fungus can move easily from one person to the ...

  5. Dos and don’ts in response priming research

    PubMed Central

    Schmidt, Filipp; Haberkamp, Anke; Schmidt, Thomas

    2011-01-01

    Response priming is a well-understood but sparsely employed paradigm in cognitive science. The method is powerful and well-suited for exploring early visuomotor processing in a wide range of tasks and research fields. Moreover, response priming can be dissociated from visual awareness, possibly because it is based on the first sweep of feedforward processing of primes and targets. This makes it a theoretically interesting device for separating conscious and unconscious vision. We discuss the major opportunities of the paradigm and give specific recommendations (e.g., tracing the time-course of priming in parametric experiments). Also, we point out typical confounds, design flaws, and data processing artifacts. PMID:22253674

  6. 48 CFR 632.702-70 - DOS policy.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... incremental funding of cost-reimbursement contracts. Fixed-price, labor-hour, and time-and-materials contracts... requirements office, justifying the need for incremental funding due to the unavailability of funds. ...

  7. Dos and Don'ts for Beginning Teachers.

    ERIC Educational Resources Information Center

    Armstrong, Coleen

    1993-01-01

    Beginning teachers are advised to pace themselves; provide disciplinary options; learn to justify their teaching; be tolerant about student gripes; use the Socratic method to elicit thoughtful responses; refrain from killing discussion, solving students' personal problems, and insulting students' intelligence; listen to veteran teachers; begin…

  8. CRONUS, A Distributed Operating System: CRONUS DOS Implementation.

    DTIC Science & Technology

    This is the final report for the second contract phase for development of the CRONUS Project. CRONUS is the name given to the distributed operating...Force Rome Air Development Center (RADC). The project was begun in 1981. The CRONUS distributed operating system is intended to promote resources...remote data, to collections of complex subsystems tailored to take advantage of a distributed architecture. One of the main contributions of CRONUS is

  9. Treating rheumatic diseases in pregnancy: dos and don'ts

    PubMed Central

    Lockshin, M D

    2006-01-01

    This paper presents a critical appraisal of the current evidence and recommendations regarding the use of pharmaceuticals and biologicals in pregnancy. Clinical experience is often at variance with published recommendations as studies have not taken into account the differences in physiology in the various stages of gestation and between animal and human pregnancies. Physicians should bear in mind that pregnancy causes disruption in several organ systems; the effects of an intervention may depend on the stage of gestation; and some effects of interventions in pregnancy may not manifest until adulthood. PMID:17038475

  10. Los Dos Mundos: Rural Mexican Americans, Another America.

    ERIC Educational Resources Information Center

    Baker, Richard

    This book explores race relations between Mexican Americans and Anglo Americans in "Middlewest," a fictitious name for an actual rural Idaho community with the highest proportion of Mexican Americans in the state. Many Mexican Americans in this predominantly agricultural area are current or former migrant workers. The first chapter…

  11. Dos and Don'ts for Beginning Teachers.

    ERIC Educational Resources Information Center

    Armstrong, Coleen

    1993-01-01

    Beginning teachers are advised to pace themselves; provide disciplinary options; learn to justify their teaching; be tolerant about student gripes; use the Socratic method to elicit thoughtful responses; refrain from killing discussion, solving students' personal problems, and insulting students' intelligence; listen to veteran teachers; begin…

  12. Dos Hermanas Chicanas: Overcoming Barriers to Professional Advancement

    ERIC Educational Resources Information Center

    Prospero, Moises

    2007-01-01

    Women and ethnic minorities face steep barriers to professional advancement, and those who rise to the executive level typically use a variety of strategies to overcome obstacles in their way. This study first reviewed the literature on barriers to professional advancement for women and ethnic minorities and the strategies that they report using…

  13. Dos and Don'ts of Writing Presidential Contracts

    ERIC Educational Resources Information Center

    Fain, Paul

    2006-01-01

    In the not-so-distant past, an employment agreement between a university president and a governing board was often nothing more than a handshake. Today, formal contracts are requirements for presidents, with boards and presidents typically relying on lawyers to extensively document terms of employment, salary and benefits, and, perhaps most…

  14. Estudo da Polarizacao dos Hiperons $\\Xi^-$ E $\\Omega^-$

    SciTech Connect

    Carvalho De Gouvea, Andre Luiz

    1995-01-01

    ln this thesis the polarization of the $\\Xi^-$ hyperon and the $\\Xi^+$ antihyperon produced in the Fermilab Experiment E791 was determined by the analysis of the weak decay $\\Xi^- \\to \\Lambda^0 + \\pi^-$. For $\\Xi^-$ produced in the interaction between a 500 GeV/c $\\pi^-$ beam and a unpolarized carbon (platinum) target in the region $p_t$ > 0.8 GeV/c and $X_F$ > 0, -10.9% ± 1.5% (-14.7% ± 3.1%) polarization was obtained perpendicular to the production plane and -5.92% ± 1.69% (-2.41%±3.53% $\\approx O$) polarization was measured for $\\Xi^+$. Evidence was also found for a polarized $\\Omega^-$ hyperon produced in the same experiment in the region $X_F$ >0, after analysis of the weak decay $\\Omega^- \\to \\Lambda^0 + K^-$.

  15. Difficulties of First Years Elementary School Teachers with the Teaching of Astronomy. (Breton Title: Dificuldades de Professores dos Anos Iniciais do Ensino Fundamental em Relação ao Ensino da Astronomia. ) Dificultades de LOS Profesores de los Primeros Años de la Escuela Primaria en Relación a la Enseñanza de la Astronomía

    NASA Astrophysics Data System (ADS)

    Langhi, Rodolfo; Nardi, Roberto

    2005-12-01

    This paper reports Primary School teachers' discourses analysis about their difficulties related to the teaching of Astronomy. It reports partial data of a master's level research carried out in the last two years, named "An exploratory study for inserting Astronomy in primary school teachers' education" (LANGHI, 2004). The study took into consideration students' and teachers' common sense conceptions about astronomical phenomena, conceptual mistakes in textbooks, and Astronomy's suggestions given by the PCN (Parâmetros Curriculares Nacionais - The Brazilian National Curriculum Standards). The paper aims to characterize teachers' difficulties, in order to provide subsides to the implementation of an initial or continuing education program. This study is justified by the fact that courses plans like these only will be adapted to the teacher's (and students') reality, if there is a primary investigation about what the teachers really need to know about Astronomy. This fact was possible here by the enunciations interpretation of a teachers' sample using semi-structured interviews, according to discourse analysis procedures. The research outcomes show difficulties related to factors like: those of personal order, methodological, on teacher's formation, educational infrastructure and other related to information sources for educators. Este artigo, que relata as dificuldades de professores em relação ao ensino da Astronomia, faz parte de um estudo exploratório para a inserção da Astronomia na formação de professores dos anos iniciais do Ensino Fundamental. Esse estudo leva em consideração as concepções alternativas de alunos e professores sobre fenômenos astronômicos, os erros conceituais em livros didáticos e as sugestões de conteúdos de Astronomia constantes nos PCN (Parâmetros Curriculares Nacionais). Caracterizar as dificuldades dos professores é a questão central deste texto, apontando para o objetivo de contribuir com subsídios para um futuro

  16. Buracos negros primordiais e astrofísica observacional

    NASA Astrophysics Data System (ADS)

    Custódio, P. S.; Horvath, J. E.

    2003-02-01

    A história da física contemporânea é pródiga em grandes descobertas (a Relatividade e a Mecânica Quântica entre as mais importantes) até meados dos anos '30. O peso destes desenvolvimentos é tão grande que outros feitos de grande porte (por exemplo, a teoria da nucleossíntese nas estrelas) são geralmente considerados como "filhotes" dos primeiros, ao menos na imaginação popular. Porém, algumas exceções à regra não-escrita são dignas de menção. Entre estas últimas está a descoberta por S.W.Hawking e colaboradores das propriedades de emissão dos buracos negros, trabalho que iniciou uma disciplina com vida própria denominada Termodinâmica de Buracos Negros.

  17. Assessment scale of risk for surgical positioning injuries.

    PubMed

    Lopes, Camila Mendonça de Moraes; Haas, Vanderlei José; Dantas, Rosana Aparecida Spadoti; Oliveira, Cheila Gonçalves de; Galvão, Cristina Maria

    2016-08-29

    to build and validate a scale to assess the risk of surgical positioning injuries in adult patients. methodological research, conducted in two phases: construction and face and content validation of the scale and field research, involving 115 patients. the Risk Assessment Scale for the Development of Injuries due to Surgical Positioning contains seven items, each of which presents five subitems. The scale score ranges between seven and 35 points in which, the higher the score, the higher the patient's risk. The Content Validity Index of the scale corresponded to 0.88. The application of Student's t-test for equality of means revealed the concurrent criterion validity between the scores on the Braden scale and the constructed scale. To assess the predictive criterion validity, the association was tested between the presence of pain deriving from surgical positioning and the development of pressure ulcer, using the score on the Risk Assessment Scale for the Development of Injuries due to Surgical Positioning (p<0.001). The interrater reliability was verified using the intraclass correlation coefficient, equal to 0.99 (p<0.001). the scale is a valid and reliable tool, but further research is needed to assess its use in clinical practice. construir e validar escala de avaliação de risco para lesões decorrentes do posicionamento cirúrgico em pacientes adultos. pesquisa metodológica, conduzida em duas etapas: construção e validação de face e de conteúdo da escala e pesquisa de campo, com a participação de 115 pacientes. a Escala de Avaliação de Risco para o Desenvolvimento de Lesões Decorrentes do Posicionamento Cirúrgico contém sete itens, sendo que cada um apresenta cinco subitens. A pontuação dessa escala varia de sete a 35 pontos, quanto maior o escore maior o risco do paciente. O Índice de Validade de Conteúdo da escala foi de 0,88. Por meio da aplicação do teste t de Student, para igualdade de médias, constatou-se validade de crit

  18. SOCIAL INCLUSION AND SOLIDARITY IN STRICT POST-GRADUATION: EXPERIENCING THE LABORATORY "SCIENTIFIC WAKE FOR THE FUTURE" (PRIMARY AND SECONDARY EDUCATION).

    PubMed

    Noronha, Silvana Aparecida Alves Corrêa de; Bernardes, Linda; Noronha, Samuel Marcos Ribeiro de; Nascimento, Fernanda Amorim de Morais; Ferreira, Lydia Masako

    2015-01-01

    cannot turn them into great researchers thus contributing to the economic, social and intellectual growth of our country through scientific research. Estimular e despertar o interesse dos alunos do ensino médio ou fundamental de escolas públicas na pesquisa e na ciência por meio de estágios de Iniciação Científica Junior no Programa de Pós-Graduação em Cirurgia Translacional da Unifesp. O público alvo para o desenvolvimento das atividades científicas foram alunos regularmente matriculados em curso de nível médio (segundos anos inicialmente) e que tivessem aprovação de sua participação pela direção da escola e responsáveis legais. Quanto aos critérios de inclusão: proximidade física com a instituição de ensino superior, assinatura do termo de consentimento pelos responsáveis dos alunos, pela diretoria da unidade escolar e pelo pesquisador. Inicialmente, os alunos realizaram avaliação diagnóstica acerca dos conhecimentos prévios de biologia, ciências e pesquisa científica. A partir daí as aulas eram elaboradas com base no resultado deste teste, para então iniciar as atividades de Iniciação Científica Junior. A escola escolhida para esta fase inicial do projeto piloto foi a Escola Estadual Rui Bloem que possui 13 salas de aula para o segundo ano do ensino médio com total de 390 alunos. Destes, 160 (41%) apresentaram-se interessados; porém, somente 16 (10%) foram elegíveis para iniciar o projeto piloto no Laboratório de Cirurgia Translacional da Unifesp. Estes alunos apresentaram rendimento médio de 50% na prova diagnóstica e deverão iniciar os próximos treinamentos no Laboratório de Biologia Celular e Molecular e também a frequentar as reuniões científicas. Nesta fase inicial houve interesse dos alunos do ensino médio e o projeto piloto apresentado estimulou e despertou interesse dos alunos de escola pública na pesquisa e na ciência. A escolha de uma escola pública foi para o acesso à universidade e proximidade. Al

  19. Thromboembolism and bleeding risk scores and predictors of cardiac death in a population with atrial fibrillation.

    PubMed

    Silva, Rose Mary Ferreira Lisboa da; Silva, Pollyana Ardavicius E; Lima, Marcos Correia; Sant'Anna, Lívia Tanure; Silva, Túlio Corrêa; Moreira, Pedro Henrique Vilela; Gandra, Robert Moreira; Cavalcanti, Túlio Ramos; Mourão, Plínio Henrique Vaz

    2017-07-01

    Atrial fibrillation (AF) is a common arrhythmia, with risk of systemic embolism and death. It presents rheumatic etiology in up to 32% of developing countries, whose anticoagulation and evolution data are scarce. to determine the predictors of cardiac death considering the clinical profile, thromboembolism and bleeding scores of patients with AF of a single center, with high prevalence of rheumatic heart disease. 302 patients with AF were studied, mean age 58.1 years; 161 women; 96 pts with rheumatic etiology. Patients underwent clinical and laboratory evaluation, measurement of risk scores and the mean follow-up of 12.8 months. 174 were using warfarin. The averages of the HAS-BLED and ATRIA scores were 1.4 and 1.2, respectively. Percent time in therapeutic range of international normalized ratio was 45.8%. Thirty patients (9.9%) had cardiac death and 41 had some type of bleeding due to warfarin. By univariate analysis, there was statistical significance between cardiac death and permanent AF, blood pressure, systolic dysfunction, R2CHADS2, CCS, EHRA and HAS-BLED. There was no association with valvular AF. By multivariate analysis, systemic arterial and pulmonary artery pressures, classification CCS and systolic dysfunction showed statistical significance. There was no association between cardiac death and valvular AF. Independent predictors of cardiac death were low measures of blood pressure, higher score CCS classification and the presence of systolic ventricular dysfunction. A fibrilação atrial (FA) é uma arritmia comum, com risco de embolia sistêmica e morte. Apresenta etiologia reumática em até 32% dos países em desenvolvimento, cujos dados de anticoagulação e evolução são escassos. Verificar as variáveis preditoras de morte cardíaca (MC) conforme o perfil clínico, os escores de tromboembolismo e de sangramento dos pacientes com FA de uma única instituição universitária, com alta prevalência de cardiopatia reumática. Foram estudados 302

  20. Medical training and nurses of Family Health strategy on worker health aspect.

    PubMed

    Mori, Érika Chediak; Naghettini, Alessandra Vitorino

    2016-06-01

    a need to raise awareness and interest of the municipality health managers and the health professionals, doctors and nurses, towards the relations work-health-disease and the need to capacitate these professionals, in order to assist the workers in a better way. Considerando a saúde do trabalhador uma das atribuições do Sistema Único de Saúde (SUS), a Atenção Primária à Saúde (APS) e a Estratégia Saúde da Família (ESF) assumem papel importante no desenvolvimento de ações no campo saúde-trabalho. No Brasil, como é grande o número de trabalhos informais e domiciliados, a ESF se torna referência nas ações de saúde do trabalhador. Assim, se a ESF não estiver atenta à relação entre atividade profissional e o adoecimento, várias doenças que acometem os trabalhadores podem sobrecarregar o sistema sem a obtenção de cura. O objetivo deste estudo foi avaliar o reconhecimento de médicos e enfermeiros da Estratégia Saúde da Família de Aparecida de Goiânia sobre doenças ocupacionais. Trata-se de um estudo qualitativo descritivo, a análise dos dados foi feita pela análise de conteúdo. O cenário deste estudo constitui-se das unidades de ESF do município de Aparecida de Goiânia, Goiás. Foram 8 Unidades Básicas de Saúde selecionadas e 16 profissionais de saúde entrevistados. Os dados foram coletados nos respectivos locais de trabalho dos participantes da entrevista, nos meses de fevereiro a abril de 2013, após aprovação pelo Comitê de Ética e Pesquisa. Os discursos foram analisados de acordo com Minayo (2007), utilizando a análise temática. As entrevistas foram gravadas e posteriormente, transcritas para sua análise. Dos 16 profissionais entrevistados, observamos que somente 3 (18,75%) passaram por capacitação profissional em saúde do trabalhador na Instituição, porém os cursos eram voltados para situações de riscos biológicos e não para o atendimento ao trabalhador. Os profissionais relataram falta de conhecimento na

  1. Fear of falling in older adults living at home: associated factors.

    PubMed

    Vitorino, Luciano Magalhães; Teixeira, Carla Araujo Bastos; Boas, Eliandra Laís Vilas; Pereira, Rúbia Lopes; Santos, Naiana Oliveira Dos; Rozendo, Célia Alves

    2017-04-10

    . A maioria dos idosos (66,5%) tinha elevado medo de cair. No modelo final de regressão multivariada, identificou-se que maior número de quedas anteriores, sexo feminino, idade mais avançada, e pior autoavaliação de saúde explicaram 37% do medo de cair entre os idosos. Os achados reforçam a necessidade da avaliação do medo de cair entre os idosos que residem no próprio domicílio, assim como o desenvolvimento e a utilização de estratégias pelos profissionais voltadas para os fatores modificáveis,de modo a reduzir as quedas e melhorar o estado de saúde, o que pode contribuir para a diminuição do medo de cair entre os idosos.

  2. Development policy for the Brazilian health industry and qualification of national public laboratories.

    PubMed

    Viana, Ana Luiza d'Ávila; Silva, Hudson Pacifico da; Ibañez, Nelson; Iozzi, Fabíola Lana

    2016-11-03

    Technological innovations play a decisive role in societies' development by contributing to economic growth and the population's welfare. The state has a key role in this process by inducing innovative behavior, strategies, and decisions. This study addresses Brazil's current policy for development of the health industry and its effects on qualification of national public laboratories by contextualizing different cycles of interaction between health policy and the industrial base, discussing the government's development strategy and the transfer and absorption of health technology (through Industrial Development Partnerships), and presenting two current partnerships involving public laboratories in the production of medicines and vaccines. Resumo: As inovações tecnológicas jogam papel decisivo no processo de desenvolvimento das sociedades, visto que contribuem para gerar crescimento econômico e bem-estar da população. O Estado possui grande importância e centralidade nesse processo, pois pode induzir fortemente o comportamento, as estratégias e as decisões relativas à inovação. O presente artigo tem por objetivo investigar a atual política de desenvolvimento produtivo em saúde no Brasil e seus reflexos sobre a capacitação dos laboratórios públicos nacionais. Para essa finalidade, contextualiza os diferentes ciclos de interação entre a política de saúde e a sua base produtiva, discute a estratégia do governo brasileiro para o desenvolvimento, a transferência e a absorção de tecnologia na área da saúde (as parcerias para o desenvolvimento produtivo) e apresenta duas parcerias vigentes envolvendo laboratórios públicos para a produção de medicamentos e vacinas.

  3. [Biomarkers of cervical carcinogenesis associated with genital human papillomavirus infection].

    PubMed

    Oliveira, Ana; Delgado, Candida; Verdasca, Nuno; Pista, Angela

    2013-01-01

    Introdução/Objetivos: A infeção persistente pelo Vírus do Papiloma Humano de alto risco (HPVar) é considerada como a causa necessária, embora não suficiente, para o desenvolvimento do cancro do colo do útero, sugerindo que outros fatores estarão envolvidos no processo de carcinogénese. Este estudo pretendeu avaliar indicadores de prognóstico da persistência da infeção por HPV, nomeadamente o estado físico e a carga viral dos HPV 16 e 18 e a superexpressão dos transcritos do RNAm dos HPV 16, 18, 31, 33 e 45, num grupo de mulheres com ou sem sintomatologia clínica e citopatológica. Material e Métodos: Foram estudadas 378 alíquotas de células epiteliais congeladas pertencentes a utentes dos centros de saúde do Serviço Nacional de Saúde e de clínicas privadas, referenciadas para teste HPV, entre Janeiro de 2007 e Dezembro de 2010. De acordo com o diagnóstico citopatológico, foram definidos cinco grupos: normal, ASCUS, LSIL, HSIL e carcinoma invasivo do colo do útero. Para a determinação do estado físico do DNA e da carga viral dos HPV 16 e 18 foi utilizada metodologia de PCR em tempo real, e para a superexpressão dos transcritos dos oncogenes E6 e E7 o sistema comercial NucliSENS EasyQ HPV®. Os indicadores foram analisados em associação com os tipos de lesão do colo do útero. Para a análise estatística foi utilizado o o programa informático SPSS versão 16.0 e o teste de Chi-Quadrado. Resultados: Os resultados mostraram ausência de associação estatisticamente significativa entre a gravidade da lesão e o estado físico do DNA dos HPV 16 e 18. A superexpressão dos transcritos do RNAm E6/E7 e a carga viral dos HPV 16 e 18 aumentaram significativamente em função do grau da lesão. Conclusões: Os resultados obtidos sugerem que a determinação do estado físico do DNA dos HPV 16 e 18, isoladamente, não constitui um indicador de prognóstico para o desenvolvimento e progressão das lesões. A superexpressão dos transcritos

  4. Endovascular revascularization of TASC C and D femoropopliteal occlusive disease using carbon dioxide as contrast.

    PubMed

    Mendes, Cynthia de Almeida; Teivelis, Marcelo Passos; Kuzniec, Sergio; Fukuda, Juliana Maria; Wolosker, Nelson

    2016-01-01

    To analyze the results of ten angioplasties of TASC C and D femoropopliteal lesions using CO2 as primary contrast in patients with no formal contraindication to iodine, aiming to decrease allergic reactions and potential nephrotoxicity in high-risk patients. We describe the results of ten angioplasties of TASC C and D femoropopliteal lesions using CO2 as primary contrast in patients with high risk for open revascularization and no formal contraindication to iodine. We analyzed feasibility of the procedures, complications, quality of the angiographic images, clinical and surgical outcomes, and costs of C and D lesions treated using CO2 as contrast medium. The use of CO2 in C and D lesions needed iodine complementation in most of the cases (nine cases) but decreased the potential nephrotoxicity of iodine contrast medium by the reduction of its volume in this group of high-risk patients. The extension of the arterial lesions was the factor that most contributed to the need for iodine supplementation due to the difficulty to visualize the refill after a long arterial occlusion. The use of CO2 as contrast in patients with C and D lesions with no restriction for iodine contrast medium was an alternative that did not dismiss the need of iodine supplementation in most of the cases, but could decrease the potential nephrotoxicity of iodine constrast medium. Analisar os resultados de dez angioplastias de lesões fêmoro-poplíteas TASC C e D utilizando CO2 como meio de contraste primário em pacientes sem restrição ao meio de contraste iodado com o objetivo de diminuir reações alérgicas e potencial de nefrotoxicidade em pacientes de alto risco. Descrevemos os resultados de dez angioplastias de lesões fêmoro-poplíteas TASC C e D utilizando CO2 como meio de contraste primário em pacientes de alto risco para revascularização aberta e sem contraindicação formal a iodo. Analisamos possibilidade de execução dos procedimentos, complicações, qualidade das imagens

  5. Apparent Motion of the Sun, Shadows of Objects and Measurement of Time in the View of Seventh Grade Students of Middle School. (Breton Title: Movimento Aparente do Sol, Sombras dos Objetos e Medição do Tempo na Visão de Alunos do Sétimo Ano do Ensino Fundamental.) Movimiento Aparente del Sol, Sombras de los Objetos y Medición del Tiempo en la Visión de Estudiantes del Séptimo Grado del Ciclo Pirmario

    NASA Astrophysics Data System (ADS)

    Iria Machado, Daniel

    2013-07-01

    The apparent motion of the Sun on the celestial sphere and the behavior of the shadows of objects over time are observable phenomena in everyday life. However, students often do not have a proper understanding of such occurrences, and can even display misconceptions about them. Therefore, we performed a research in order to know students' notions about these subjects and to evaluate the contribution to their understanding brought about by an activity performed with an interactive sundial in an informal learning environment. We investigated the ideas of 43 students from the seventh grade of middle school by applying a test with open questions before and after an activity with an analemmatic sundial, conducted by a monitor. A significant proportion of students were initially unaware of most of the phenomena treated. The intervention performed helped the students to assimilate new concepts, providing the contact with new phenomena and to a lesser degree, the development of explanations about them, indicating an educational potential of this action. However, the contribution to the understanding of some of the ideas explored was small, pointing to the need to make additional observations, studies and discussions. O movimento aparente do Sol na esfera celeste e o comportamento das sombras dos objetos com o passar do tempo são fenômenos observáveis no dia a dia. No entanto, muitas vezes os estudantes não possuem uma compreensão adequada de tais ocorrências, podendo inclusive exibir concepções alternativas a seu respeito. Por isso, efetuou-se uma pesquisa com o intuito de conhecer as noções dos alunos sobre esses temas e avaliar a contribuição para seu entendimento propiciada por uma atividade feita com um relógio de Sol interativo, em um ambiente de ensino informal. Foram investigadas as ideias de 43 alunos do sétimo ano do Ensino Fundamental mediante a aplicação de um teste com questões abertas antes e depois de uma atividade com um relógio de Sol

  6. A Visão do Universo Segundo a Concepção de um Grupo de Alunos do Ensino Médio de São Paulo

    NASA Astrophysics Data System (ADS)

    Araújo, M. A. A.; Elias, D. C. N.; Amaral, L. H.; Araújo, M. S. T.; Voelzke, M. R.

    2005-12-01

    Nesse trabalho foi identificada por meio de um questionário a visão de mundo sobre o Universo espaço e tempo entre 270 estudantes de Ensino Médio de três escolas de São Paulo. Constatou-se pouco conhecimento dos temas investigados sendo que apenas 20% dos alunos relacionaram as semanas com as fases da lua enquanto 28% associaram as estações do ano à inclinação do eixo de rotação da Terra e 23% tinham noções das distâncias entre objetos celestes próximos da Terra. Enquanto 56% conseguiram relacionar o Big Bang com a origem do Universo verificou-se que 37% reconheciam ano-luz como unidade de distância e 60% reconheciam o Sol como uma estrela. Apesar de 60% dos alunos indicarem a escola como principal fonte dos conhecimentos de astronomia seus conceitos ainda são inadequados havendo necessidade de aprimoramento da abordagem desses conteúdos pois apesar de popular a astronomia é veiculada de maneira pouco esclarecedora e com imprecissões.

  7. [Autism and Early Neurodevelopmental Milestones].

    PubMed

    Ferreira, Xavier; Oliveira, Guiomar

    2016-03-01

    Introdução: A perturbação do espectro do autismo, neste texto também designada por autismo, é uma patologia crónica do neurodesenvolvimento, que se manifesta precocemente na infância por alterações da interação social, comunicação e comportamento repetitivo. Não estando disponíveis biomarcadores específicos, o diagnóstico baseia-se exclusivamente na avaliação clínica. O objetivo deste estudo é verificar quais os marcadores precoces do desenvolvimento psicomotor ou neurodesenvolvimento, que se correlacionam significativamente com a gravidade da clínica central do autismo, quocientes de desenvolvimento e com a função adaptativa. Material e Métodos: Procedemos ao estudo retrospetivo de uma população de 1 572 indivíduos com o diagnóstico de autismo seguidos na Unidade de Neurodesenvolvimento e Autismo do Centro de Desenvolvimento da Criança do Hospital Pediátrico do Centro Hospitalar e Universitário de Coimbra. Analisámos seis marcadores precoces do desenvolvimento psicomotor: idades de aquisição 'da marcha', 'das primeiras palavras', 'das primeiras frases', 'do controlo de esfíncter vesical diurno', 'do controlo de esfíncter vesical noturno' e de início das primeiras queixas. Posteriormente dividimos a amostra em três subgrupos de gravidade clínica segundo a escala Childhood Autism Rating Scale e pesquisamos diferenças significativas entre os três subgrupos relativamente aos seis marcadores definidos. Resultados: O marcador 'idade de aquisição das primeiras frases' foi, de entre os seis, aquele que se correlacionou mais fortemente com as variáveis da clínica de autismo, quocientes de desenvolvimento/inteligência e comportamento ou função adaptativa. Na divisão da amostra em subgrupos de gravidade clínica, foi o de maior gravidade que mostrou idades de aquisição dos marcadores do neurodesenvolvimento mais tardias e idades mais precoces de manifestação das primeiras queixas. Discussão: Este estudo vem demonstrar a

  8. Use of elephant grass for energy production in Campos dos Goytacazes-RJ, Brazil.

    PubMed

    Daher, R F; Souza, L B; Gravina, G A; Machado, J C; Ramos, H C C; Silva, V Q R; Menezes, B R S; Schneider, L S A; Oliveira, M L F; Gottardo, R D

    2014-12-19

    Elephant grass is a tropical forage plant widely distributed throughout Brazil. It was first exclusively used in the livestock sector as cattle feed. The grass is characterized by its high productivity and photosynthetic capacity and is considered as an alternative source of renewable energy. Here, we estimated the general combining ability of the parents and specific combining ability of the hybrids based on morpho-agronomic biomass-quality traits. The experiment was conducted in a randomized block design with 3 replicates. The diallel was composed of 16 hybrids and 2 groups of genitors. In the diallel analysis of variance, we observed a significant difference among treatments. A significant difference was observed among genitors for dry matter production (DMP). For the general combining ability of group 1, the traits leaf blade width, DMP, height, percentage of neutral detergent fiber, percentage of hemicellulose, percentage of lignin, percentage of acid detergent fiber, and percentage of cellulose were significant. For the estimates of general combining ability of DMP, parents Porto Rico 534-B, Vruckwona, Taiwan A-146, and Mercker S. E. A. were 0.4748, 3.2819, 1.1659, and 0.4317. The parents of Mercker S. E. A. and Porto Rico 534-B produced the highest percentage of detergent fiber and percentage of lignin with values of 0.1482 and 0.0856. Thus, parents Vruckwona, Porto Rico 534-B, and Taiwan A-146 are promising for integration into breeding programs. The best hybrid combinations for DMP were 1 x 5, 1 x 8, 2 x 6, 3 x 7, and 4 x 5.

  9. The Politics of Hispanic Education. Un Paso pa'lante y dos pa'tras.

    ERIC Educational Resources Information Center

    Meier, Kenneth J.; Stewart, Joseph, Jr.

    This book presents an in-depth examination of 142 U.S. school districts (containing at least 5,000 students and 5 percent Hispanic enrollment) in order to understand Hispanic inequities in education and what can be done to correct these inequities. Chapter 1 presents political theory of educational policy. Chapter 2 presents an overview of the…

  10. One? "Dos" Drei. A Study of Code Switching in Child Trilingualism

    ERIC Educational Resources Information Center

    Davidiak, Elena

    2010-01-01

    This longitudinal study focuses on the language production of two siblings, aged 6 and 9 at the beginning of the data collection period, who have been brought up in a bilingual family in New York. The parents of the two girls are native speakers of German and Spanish, respectively, and English for them is the language of education and the larger…

  11. Ensuring the relocatability of programs in the operational system DOS YeS

    NASA Technical Reports Server (NTRS)

    Novoseltsev, S. K.; Orlov, I. G.; Chesalin, A. S.

    1979-01-01

    Specific modifications in the Disk Operational System Unified Series to insure the relocatability of programs stored permanently in the core image library is described. A self-relocating method for loading programs into the working memory with re-editing all the programs recorded in the core image library is presented. The modified linkage editor can be included in a relocation dictionary containing data about each address constant at the assembly stage at the request of the programmer. The relocation dictionary increases the dimension of the RL-phase in comparison with the dimension of this same phase when edited by the standard method, making possible the creation of multiphase program complexes. Generation and use of the modified system using Assembly language is described. An example of the use of the system is given, and limitations of the use of the relocatable programs in the modified system are outlined.

  12. Dos and Donts for Conditional Acceptance of Nonconforming Supplies or Services

    DTIC Science & Technology

    2016-06-01

    have quite a few options in dealing with this prob-lem, including conditional acceptance. The purpose of this article is, first, to share a personal ...accom- modate that request. Out of all the choices (reject, rework at no additional cost, replacement or terminate for default) avail- able under FAR...sub-part 46.407 to the government, conditional acceptance was probably thought to be the easiest and most expeditious choice . But for whom

  13. Denoised ordered subset statistically penalized algebraic reconstruction technique (DOS-SPART) in digital breast tomosynthesis

    NASA Astrophysics Data System (ADS)

    Garrett, John; Li, Yinsheng; Li, Ke; Chen, Guang-Hong

    2017-03-01

    Digital breast tomosynthesis (DBT) is a three dimensional (3D) breast imaging modality in which projections are acquired over a limited angular span around the compressed breast and reconstructed into image slices parallel to the detector. DBT has been shown to help alleviate the breast tissue overlapping issues of two dimensional (2D) mammography. Since the overlapping tissues may simulate cancer masses or obscure true cancers, this improvement is critically important for improved breast cancer screening and diagnosis. In this work, a model-based image reconstruction method is presented to show that spatial resolution in DBT volumes can be maintained while dose is reduced using the presented method when compared to that of a state-of-the-art commercial reconstruction technique. Spatial resolution was measured in phantom images and subjectively in a clinical dataset. Noise characteristics were explored in a cadaver study. In both the quantitative and subjective results the image sharpness was maintained and overall image quality was maintained at reduced doses when the model-based iterative reconstruction was used to reconstruct the volumes.

  14. Dos Puertorriquenos Visitan Puerto Rico (Two Puerto Ricans Visit Puerto Rico).

    ERIC Educational Resources Information Center

    Tuttle, Harry Grover

    These materials for Spanish instruction are based on the meeting and friendship of two Puerto Ricans arriving in Puerto Rico for visits to their hometowns, their discussions of Puerto Rican life, and a sightseeing tour of San Juan. Introductory passages to the visitors' dialogues are in English, and dialogues are in Spanish, with photographs,…

  15. Nuevos rangos altitudinales para dos especies de la avifauna de Nicaragua

    Treesearch

    M.A. Torrez; Wayne Arendt; I. Castillo

    2015-01-01

    We document the elevational range expansions of two Nicaraguan bird species, scaled pigeon (Patagioenas speciosa) and collared plover (Charadrius collaris). The previously reported elevational range of Patagioenas speciosa was sea level to 600 m. We observed the species in shade coffee at Santa Maura farm at an elevation of 1115 masl. Historically, the second species,...

  16. Organogel formation rationalized by Hansen solubility parameters: dos and don'ts.

    PubMed

    Bonnet, Julien; Suissa, Gad; Raynal, Matthieu; Bouteiller, Laurent

    2014-05-14

    Some organic compounds gelate liquids by forming a network of anisotropic fibres. Hansen solubility parameters can be used to predict the range of liquids that are likely to be gelled by any given gelator. We critically review the various approaches recently proposed in the literature. In particular, we discuss the shape of the gelation domain, the relevance of the Teas plot representation and the use of group contribution calculations. We also propose an improved scheme for the solubility tests, and a detailed procedure for the determination of the gelation domain.

  17. One? "Dos" Drei. A Study of Code Switching in Child Trilingualism

    ERIC Educational Resources Information Center

    Davidiak, Elena

    2010-01-01

    This longitudinal study focuses on the language production of two siblings, aged 6 and 9 at the beginning of the data collection period, who have been brought up in a bilingual family in New York. The parents of the two girls are native speakers of German and Spanish, respectively, and English for them is the language of education and the larger…

  18. Dos Puertorriquenos Visitan Puerto Rico (Two Puerto Ricans Visit Puerto Rico).

    ERIC Educational Resources Information Center

    Tuttle, Harry Grover

    These materials for Spanish instruction are based on the meeting and friendship of two Puerto Ricans arriving in Puerto Rico for visits to their hometowns, their discussions of Puerto Rican life, and a sightseeing tour of San Juan. Introductory passages to the visitors' dialogues are in English, and dialogues are in Spanish, with photographs,…

  19. Notas sobre dos autores mejicoamericanos de California (Notes on Two Mexican-American Authors in California).

    ERIC Educational Resources Information Center

    Moesser, Alba

    This paper discusses the work of two Mexican American authors, Jose A. Villerreal and Richard Vazquez, using "Pocho" by Villarreal and "Chicano" by Vazquez as the focus for discussion. Both authors describe the world of Mexican Americans and their social conditions, and both underscore the need for conserving their native…

  20. Land disposal of San Luis drain sediments, Panoche Water District, South Dos Palos, California

    SciTech Connect

    Zawislanski, Peter; Benson, Sally; TerBerg, Robert; Borglin, Sharon

    2002-07-01

    Lawrence Berkeley National Laboratory (LBNL), LFR Levine-Fricke (LFR), the U.S. Bureau of Reclamation (USBR) and the Panoche Water District, have completed a pilot-scale test of the viability of land application of selenium- (Se-) enriched San Luis Drain (SLD) sediments. The project was initiated in October 1998 by LBNL. LFR assumed the role of primary subcontractor on the project in July 2001. Substantial portions of this report, describing work performed prior to November 2000, were previously prepared by LBNL personnel. The data set, findings, and recommendations are herein updated with information collected since November 2000. Local land disposal is an attractive option due to its low cost and the proximity of large areas of available land. Two modes of disposal are being tested: (1) the application to a nearby SLD embankment, and (2) the application to and incorporation with nearby farm soils. The study of these options considers the key problems that may potentially arise from this approach. These include disturbance of SLD sediments during dredging, resulting in increased downstream Se concentrations; movement of the land-applied Se to groundwater; reduced productivity of farm crops; and Se uptake by wild and crop plants. This report describes field and laboratory activities carried out from 1998 through February 2002, and results of these investigations.

  1. Dos Idiomas, Un Mundo. Dual Language Project. Title VII Biennial Evaluation Report, 1995-97.

    ERIC Educational Resources Information Center

    Ernest, Harishini M.; Gonzalez, Rosa M.

    This is an evaluation of the first 2 years of a 5-year comprehensive Bilingual Education grant funded by Title VII Part A of the Improving America's Schools Act of 1994 in the Austin Independent School District (AISD) (Texas). The grant awarded to the AISD funds a program of Developmental Bilingual Education at two elementary schools where more…

  2. NASA Glenn Steady-State Heat Pipe Code Users Manual, DOS Input. Version 2

    NASA Technical Reports Server (NTRS)

    Tower, Leonard K.

    2000-01-01

    The heat pipe code LERCHP has been revised, corrected, and extended. New features include provisions for pipes with curvature and bends in "G" fields. Heat pipe limits are examined in detail and limit envelopes are shown for some sodium and lithium-filled heat pipes. Refluxing heat pipes and gas-loaded or variable conductance heat pipes were not considered.

  3. Home before You Know It = De regres en casa en un dos por tres.

    ERIC Educational Resources Information Center

    Vida Health Communications, Inc., Cambridge, MA.

    The arrival of a newborn requires a great deal of adjustment. Intended for new and expectant parents, this booklet and companion video provide practical advice and hands-on demonstrations of the essentials of mother and baby care, from birth to the first visit to the pediatrician. The first part of the booklet, which comes in both English- and…

  4. Lessons Learned from Sleep Education in Schools: A Review of Dos and Don'ts.

    PubMed

    Blunden, Sarah; Rigney, Gabrielle

    2015-06-15

    Sleep duration and quality are associated with negative neuropsychological and psychosocial outcomes in children and adolescents. However, community awareness of this is low and sleep education programs in schools are attempting to address this issue. Several studies now exist assessing the efficacy of these sleep education programs for improving sleep knowledge, sleep hygiene and sleep patterns. This paper presents these sleep education programs, most particularly, it presents the strengths and weaknesses of the current available studies in the hope that this can identify areas where future sleep education programs can improve. A systematic search of all school-based sleep education studies in adolescents was undertaken. Studies were scrutinized for author, teacher and participant comment regarding strengths and limitations of each study, which were then extracted and summarized. Two specific types of sleep education programs emerged from the review, those that sought to change sleep behavior and those that sought simply to disseminate information. Issues that dictated the strength or weakness of a particular study including who delivers the program, the theoretical basis, the tools utilized to measure sleep patterns, the content, and their capacity to engage students were assessed. Sleep education was considered important by teachers, students and parents alike. Future sleep education programs need to take into account lessons learned from previous sleep education efforts in order to maximize the potential for sleep education programs to improve the sleep health of our young people. A commentary on this article appears in this issue on page 595. © 2015 American Academy of Sleep Medicine.

  5. Aspectos linguisticos dos emprestimos em portugues (Linguistic Aspects of Adaptation into Portuguese).

    ERIC Educational Resources Information Center

    Harmon, Ronald M.

    1994-01-01

    Examines the process through which modern Portuguese borrows from other languages, mainly French and English. Portuguese adapts these derivatives to conform to its own rules of phonology, morphology, and semantics. (four references) (Author/CK)

  6. "Mi Hija Vale Dos Personas": Latino Immigrant Parents' Perspectives about Their Children's Bilingualism

    ERIC Educational Resources Information Center

    Worthy, Jo; Rodriguez-Galindo, Alejandra

    2006-01-01

    This paper presents the voices of 16 Latino immigrant parents whose children were upper elementary students in a bilingual education class in the southwestern United States. In interviews that focused on their children's language learning and usage, the parents spoke of a commitment to a better life for their children. All believed that English…

  7. Unidad: Las influencias culturales en el arte mexicana (Unit: Cultural Influences in Mexican Art). Dos semanas.

    ERIC Educational Resources Information Center

    Finere, Neal

    This two-week unit, appropriate for bilingual education settings as well as foreign language programs, deals with the three primary cultural influences found in Mexican contemporary art. The multisensory materials, pragmatic focus, and direct creative student involvement are designed to make it a microcosmic, real-life experience. The first part…

  8. Dos and Don'ts of Giving OTC Cough and Cold Medicines to Your Child

    MedlinePlus

    ... Choices Weight Loss and Diet Plans Nutrients and Nutritional Info Sugar and Sugar Substitutes Exercise and Fitness ... Choices Weight Loss and Diet Plans Nutrients and Nutritional Info Sugar and Sugar Substitutes Exercise and Fitness ...

  9. 33 CFR 104.255 - Declaration of Security (DoS).

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Officer (FSO), or their designated representative, of any vessel or facility with which it interfaces. (1) For a vessel-to-facility interface, prior to arrival of a vessel to a facility, the FSO and Master... 1 and 2, VSOs of vessels that frequently interface with the same facility may implement a continuing...

  10. 33 CFR 104.255 - Declaration of Security (DoS).

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Officer (FSO), or their designated representative, of any vessel or facility with which it interfaces. (1) For a vessel-to-facility interface, prior to arrival of a vessel to a facility, the FSO and Master... 1 and 2, VSOs of vessels that frequently interface with the same facility may implement a continuing...

  11. Home before You Know It = De regres en casa en un dos por tres.

    ERIC Educational Resources Information Center

    Vida Health Communications, Inc., Cambridge, MA.

    The arrival of a newborn requires a great deal of adjustment. Intended for new and expectant parents, this booklet and companion video provide practical advice and hands-on demonstrations of the essentials of mother and baby care, from birth to the first visit to the pediatrician. The first part of the booklet, which comes in both English- and…

  12. Von Willebrand disease - the 'Dos' and 'Don'ts' in surgery.

    PubMed

    Miesbach, Wolfgang; Berntorp, Erik

    2017-02-01

    Von Willebrand disease (VWD) is the most common genetic bleeding disorder. VWD is caused by a deficiency or dysfunction of von Willebrand factor (VWF), a plasma protein that mediates the initial adhesion of platelets at sites of vascular injury and binds and stabilises coagulation factor VIII (FVIII) in the blood. Prophylaxis of surgical bleeding in patients with VWD requires consideration of the individual situation, including the type of procedure and the bleeding rate, before decisions about treatment type, dose, duration and adjunctive therapy with antifibrinolytics or antithrombotic prophylaxis can be made. Although desmopressin (DDAVP)-stimulated release of endogenous VWD is an effective treatment strategy in many patients, plasma concentrates containing VWF are the preferred option for most patients undergoing surgical procedures. Recommendations for the management of surgery in patients with VWD are summarised, including the severity of VWD and the type of the surgical procedure.

  13. Unidad: Las influencias culturales en el arte mexicana (Unit: Cultural Influences in Mexican Art). Dos semanas.

    ERIC Educational Resources Information Center

    Finere, Neal

    This two-week unit, appropriate for bilingual education settings as well as foreign language programs, deals with the three primary cultural influences found in Mexican contemporary art. The multisensory materials, pragmatic focus, and direct creative student involvement are designed to make it a microcosmic, real-life experience. The first part…

  14. "Being Present in the World": A Conversation with Professor Jose Marques dos Santos

    ERIC Educational Resources Information Center

    Katz, Richard N.; Dodds, Ted

    2008-01-01

    The University of Porto was awarded the European University Information Systems (EUNIS) Elite Award for its innovative application of information technology to a European university. This university--nearly one hundred years old--is pressing hard, on a number of fronts, to place itself in the top rank of European universities. The Rector of the…

  15. A social media primer for professionals: digital dos and don'ts.

    PubMed

    Bernhardt, Jay M; Alber, Julia; Gold, Robert S

    2014-03-01

    Social media sites have become powerful and important tools for health education, promotion, and communication activities as they have dramatically grown in popularity. Social media sites also offer many features that can be used for professional development and advancement. When used wisely and prudently, social media sites and platforms offer great potential for professional development by building and cultivating professional networks, as well as sharing information to increase one's recognition and improve one's reputation. They also provide a medium for increasing one's knowledge and awareness of timely news and trends by following important organizations, opinion leaders, and influential professionals. When used unwisely and imprudently, there is the potential to delay, damage, or even destroy one's professional and personal life. In this commentary, we offer recommendations for using Facebook, LinkedIn, and Twitter for professional development and caution against online behaviors that may have negative professional consequences. In summary, we believe that the strengths and benefits of social media for professional advancement and development far outweigh the risks and encourage health promotion professionals to properly engage these powerful tools.

  16. Buscando Su Voz en Dos Culturas = Finding Your Voice in Two Cultures.

    ERIC Educational Resources Information Center

    Cline, Zulmara

    1998-01-01

    An administrator/former teacher ponders difficulties of living in two cultures: a professional world that respects her degrees and credentials and a Latina world that questions pursuit of the "American dream." Although she used her American voice to coax a Latina student back to school, she sympathized with the mother's family-centered…

  17. The Puerto Ricans--Two Communities, One Culture. (Los Puertorriquenos--Dos Comunidades, Una Cultura.)

    ERIC Educational Resources Information Center

    Vivo, Paquita

    1980-01-01

    Puerto Rican roots stem from the ethnic mixture of Indians, Europeans, and Africans. This article describes the advent of each of the groups on the island, the historical and cultural impact each made, and the retention of heritage among Puerto Rican migrants to the U.S. (DS)

  18. Influencias africanas na lingua brasileira dos terreiros (African Influences in Brazilian Language of the Voodoo Rites).

    ERIC Educational Resources Information Center

    Megenney, William W.

    1991-01-01

    Discusses how determination of lexical items with Sub-Saharan origin in songs of voodoo rites of candomble and umbanda in southern and northeastern Brazil is complicated by factors like existence of phonological correspondence without accompanying semantic correspondence, difficulty of determining meaning of word in a given text, and high…

  19. Estudio de dos cúmulos abiertos del tercer cuadrante galáctico

    NASA Astrophysics Data System (ADS)

    Solivella, G. R.; Giorgi, E. E.; Vázquez, R. A.; De Laurenti, M. A.

    2017-10-01

    Results from photometric observations in the open clusters Ruprecht 42 and Ruprecht 43 are presented. In the last case spectroscopic observations were added. The open cluster entity of Ruprecht 42, not previously studied, is confirmed. While the preliminary analysis of Ruprecht 43 suggests that it does not exist, at the same time evidences of a blue distant population in the same direction are found. The connection of both clusters with the near spiral structure is commented.

  20. The Puerto Ricans--Two Communities, One Culture. (Los Puertorriquenos--Dos Comunidades, Una Cultura.)

    ERIC Educational Resources Information Center

    Vivo, Paquita

    1980-01-01

    Puerto Rican roots stem from the ethnic mixture of Indians, Europeans, and Africans. This article describes the advent of each of the groups on the island, the historical and cultural impact each made, and the retention of heritage among Puerto Rican migrants to the U.S. (DS)

  1. Buscando Su Voz en Dos Culturas = Finding Your Voice in Two Cultures.

    ERIC Educational Resources Information Center

    Cline, Zulmara

    1998-01-01

    An administrator/former teacher ponders difficulties of living in two cultures: a professional world that respects her degrees and credentials and a Latina world that questions pursuit of the "American dream." Although she used her American voice to coax a Latina student back to school, she sympathized with the mother's family-centered…

  2. DOS Design/Application Tools System/Segment Specification. Volume 3

    DTIC Science & Technology

    1990-09-01

    development tools by automating and coordin- ating information exchange between tools, through use of the CRONUS distributed system and the ONTOS object...3.1.7.2. Cronus to CSCI Interfaces ...................................................................... 24 3.1.7.2. 1. Cronus to Tool Integration...Framework CSCI Interface .................. 24 3 1.7.2.2. Cronus to Tool CSCI Interfaces ...................................................... 25 3

  3. 33 CFR 101.505 - Declaration of Security (DoS).

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ..., or between vessels in the case of a vessel-to-vessel activity, as to the respective security measures each must undertake during a specific vessel-to-facility interface, during a series of interfaces between the vessel and the facility, or during a vessel-to-vessel activity. (b) Details as to who must...

  4. 33 CFR 101.505 - Declaration of Security (DoS).

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ..., or between vessels in the case of a vessel-to-vessel activity, as to the respective security measures each must undertake during a specific vessel-to-facility interface, during a series of interfaces between the vessel and the facility, or during a vessel-to-vessel activity. (b) Details as to who must...

  5. 33 CFR 104.255 - Declaration of Security (DoS).

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Officer (FSO), or their designated representative, of any vessel or facility with which it interfaces. (1) For a vessel-to-facility interface, prior to arrival of a vessel to a facility, the FSO and Master... 1 and 2, VSOs of vessels that frequently interface with the same facility may implement a...

  6. 33 CFR 104.255 - Declaration of Security (DoS).

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Officer (FSO), or their designated representative, of any vessel or facility with which it interfaces. (1) For a vessel-to-facility interface, prior to arrival of a vessel to a facility, the FSO and Master... 1 and 2, VSOs of vessels that frequently interface with the same facility may implement a...

  7. 33 CFR 104.255 - Declaration of Security (DoS).

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Officer (FSO), or their designated representative, of any vessel or facility with which it interfaces. (1) For a vessel-to-facility interface, prior to arrival of a vessel to a facility, the FSO and Master... 1 and 2, VSOs of vessels that frequently interface with the same facility may implement a...

  8. VizieR Online Data Catalog: The Solar Twin Planet Search. IV. (dos Santos+, 2016)

    NASA Astrophysics Data System (ADS)

    Dos Santos, L. A.; Melendez, J.; Do Nascimento, J.-D. Jr; Bedell, M.; Ramirez, I.; Bean, J. L.; Asplund, M.; Spina, L.; Dreizler, S.; Alves-Brito, A.; Casagrande, L.

    2016-07-01

    Ages, the measured projected rotational velocities (vsini) and stellar parameters of the 81 solar twins and the Sun. The ages of all solar twins and stellar parameters for HIP68468 were obtained by Tucci Maia et al. (2016A&A...590A..32T). Stellar parameters for the other solar twins were obtained by Ramirez et al. (2014A&A...572A..48R). The vsini were measured by line profile fitting using red spectra from HARPS (R=115000). Macroturbulence velocities were inferred from the scaling Eq. 2 in our study. (1 data file).

  9. A Methodology for the Evaluation of Structural Design Software for DOS- Based Microcomputers

    DTIC Science & Technology

    1992-07-01

    09235 Fort Iheiri 92310 SETAF ATTN: AFZ7-EH USA Eap Activty. Capital Arc ATTN: AESE-EN D 09613 Fot Hood 76544 ATrN: Lbrwy 22211 ATTN: AESE-EN 09630 ATTN...Ehnendorf AFB. AK 99506-5001 HQ AFLCODEE Wright-Patemno AFB. OH 45433-5001 HQ AFRES/DEE Robhin AFB, DC 20334-5000 HQ AFSCODEE Andrews AFB. DC DC 20334

  10. Portulano frente a Landsat: Dos sistemas de georreferenciacion para el Estrecho de Gibraltar

    NASA Astrophysics Data System (ADS)

    Barranco Molina, Carlos

    The purpose of this research is to study and an compare two different images of the same area, from geographical, topographical and historical perspectives. The main differences between them are the temporal localization and the techniques and tools required in the process of getting both images. One of them is a 17th century map and the other is a contemporary satellite image. Any cartographical document would be expected to be precise, exact and cutting edge thanks to the application of the new technologies to cartography, geodesy and computing. The document can therefore be considered as insuperable and definitive. In this context, this research is a starting point for my future doctoral dissertation which will deal with the importance of the portulano maps in the Scientific Revolution of the 15th and 16 th century.

  11. Deflecting Hurakan: Enhancing DOD and DOS Interagency Hurricane Response Operations in Central America

    DTIC Science & Technology

    2010-04-01

    INformation ―Coordinacion logistica y vías de acceso en la RAAN - Informacion actualizada‖, 15 Sep 2007; http://www.logcluster.org/ops/hurricane-felix...coordination/coordinacion- logistica -y- vias-de-acceso-en-la-raan-informacion-actualizada. 80 MC1 Michael Wimbish, ―U.S. Military Forces Wrap up Hurricane...Dept04.htm (accessed 02 March 2010). Puente Aéreo (Air Bridge) Information ―Coordinacion logistica y vías de acceso en la RAAN – Informacion

  12. Entre Dos Mundos/Between Two Worlds: Bicultural Development in Context

    ERIC Educational Resources Information Center

    Bacallao, Martica L.; Smokowski, Paul R.

    2009-01-01

    How do Mexican immigrant adolescents balance different, and often oppositional, cultural influences in the acculturation process? In this article, we explore how acculturating adolescents absorb cultural messages and go about creating their (multiple) identities. Guided by Alternation Theory, in-depth qualitative interviews were conducted with 12…

  13. Sobre las soluciones acotadas del problema instantáneo de dos cuerpos

    NASA Astrophysics Data System (ADS)

    Altavista, C.

    La demostración se basa en el hecho de que las integrales del problema de los N-cuerpos admiten componentes en el campo complejo según las raíces n-ésimas de la unidad. Definida la matriz unitaria correspondiente, la fórmula de Cayley permite transformar la matriz unitaria en una matriz hermitiana. Utilizando como parámetros los cosenos direccionales de un sistema de coordenadas orbitales referidos a un sistema de referencia fijo, puede construirse, utilizando el operador hermitiano antes definido, una forma cuadrática cuyas raíces mínima y máxima definen las cotas respectivas de los movimientos de los mencionados cosenos direccionales.

  14. SERUM LEPTIN LEVENS AND HEPATOCELLULAR CARCINOMA: REVIEW ARTICLE.

    PubMed

    Andrighetto, Luiza Vitelo; Poziomyck, Aline Kirjner

    2016-01-01

    Hepatocellular carcinoma is one of the most frequent types of malignant tumors in the world. There is growing evidence of the relationship between it development and obesity. The mechanism that links obesity to cancer is still not fully understood; however, it is essential to the understanding the adipose tissue in metabolic changes related to obesity and hepatocellular carcinoma. To review the influence of serum leptin levels in patients with hepatocelular carcinoma. Systematic review of the literature based on the methodology of the Cochrane Institute. The search for articles was in the database: Science Direct, Scielo, Medline, Lilacs e Pubmed. The key words used were hepatocellular carcinoma, leptin, adipokine. After evaluation of individual studies, were selected seven studies. The results previously studied are still inconsistent and contradictory, and leptin can be effectively involved in the occurrence and development of hepatocellular carcinoma. Therefore, it is necessary to develop prospective, well-designed and conducted focusing on the role and specific mechanisms of this hormone in patients with hepatocellular carcinoma, so that new correlations can be properly supported. O carcinoma hepatocelular é um dos tipos mais frequentes de tumores malignos no mundo. Há crescentes evidências da relação entre o seu desenvolvimento e a obesidade. O mecanismo que os relaciona ainda não é completamente entendido. Entretanto é essencial a compreensão do tecido adiposo nas alterações metabólicas relacionadas à obesidade e ao câncer. Revisar a influência dos níveis séricos de leptina em pacientes com carcinoma hepatocelular. Trata-se de revisão bibliográfica baseada na metodologia do Instituto Cochrane; a busca de dados foi realizada na base de dados Science Direct, Scielo, Medline, Lilacs e Pubmed, empregando as seguintes descritores: hepatocellular carcinoma, leptin, adipokine. Após avaliação individual dos artigos selecionaram-se sete estudos

  15. Protótipo do primeiro interferômetro brasileiro - BDA

    NASA Astrophysics Data System (ADS)

    Cecatto, J. R.; Fernandes, F. C. R.; Neri, J. A. C. F.; Bethi, N.; Felipini, N. S.; Madsen, F. R. H.; Andrade, M. C.; Soares, A. C.; Alonso, E. M. B., Sawant, H. S.

    2004-04-01

    A interferometria é uma poderosa ferramenta usada para investigar estruturas espaciais de fontes astrofísicas fornecendo uma riqueza de detalhes inatingível pelas técnicas convencionais de imageamento. Em particular, a interferometria com ondas de rádio abre o horizonte de conhecimento do Universo nesta ampla banda do espectro eletromagnético, que vai de cerca de 20 kHz até centenas de GHz já próximo ao infravermelho, e que está acessível a partir de instrumentos instalados em solo. Neste trabalho, apresentamos o interferômetro designado por Arranjo Decimétrico Brasileiro (BDA). Trata-se do primeiro interferômetro a ser desenvolvido no Brasil e América Latina que já está em operação na fase de protótipo. Apresentamos o desenvolvimento realizado até o momento, o sítio de instalação do instrumento, o protótipo e os principais resultados dos testes de sua operação, as perspectivas futuras e a ciência a ser desenvolvida com o instrumento nas fases II e III. Neste trabalho é dada ênfase ao desenvolvimento, testes de operação e principais resultados do protótipo. É discutida brevemente a ciência que pode ser feita com o instrumento. Tanto os detalhes técnicos quanto os principais parâmetros estimados para o instrumento nas próximas fases de desenvolvimento e o desempenho do protótipo serão publicados em breve.

  16. Development, health, and international policy: the research and innovation dimension.

    PubMed

    Buss, Paulo Marchiori; Chamas, Claudia; Faid, Miriam; Morel, Carlos

    2016-11-03

    This text main objective is to discuss development and health from the perspective of the influence of global health governance, using as the tracer the dimension of research, development, and innovation policies in health, which relate to both important inputs for the health system, like drugs and medicines, vaccines, diagnostic reagents, and equipment, and innovative concepts and practices for the improvement of health systems and public health. The authors examine the two main macro-processes that influence development and health: the post-2015 Development Agenda and the process under way in the World Health Organization concerning research and development, intellectual property, and access to health inputs. The article concludes, first, that much remains to be done for the Agenda to truly represent a coherent and viable international political pact, and that the two macro-processes related to innovation in health need to be streamlined. But this requires democratization of participation by the main stakeholders - patients and the general population of the poorest countries - since this is the only way to overcome a "zero sum" result in the clash in the current debates among member State representatives. Resumo: O objetivo central deste texto é discutir desenvolvimento e saúde sob a ótica da influência da governança da saúde global, utilizando como traçador a dimensão das políticas de pesquisa, desenvolvimento e inovação em saúde, que se referem, de um lado, a insumos importantes para o sistema de saúde - como fármacos e medicamentos, vacinas, reativos para diagnóstico e equipamentos e, de outro, a conceitos e práticas inovadoras para o aperfeiçoamento dos sistemas de saúde e da saúde pública. Examina os dois principais macroprocessos que influenciam o desenvolvimento e a saúde: a Agenda do Desenvolvimento para o pós-2015 e o processo sobre pesquisa e desenvolvimento, propriedade intelectual e acesso a insumos em saúde em curso na Organiza

  17. A Concepção de Universo entre Alunos do Ensino Médio de São Paulo e suas Fontes de Aquisição

    NASA Astrophysics Data System (ADS)

    Araújo, M. A. A.; Elias, D. C. N.; Amaral, L. H.; Araújo, M. S. T.; Voelzke, M. R.

    2006-08-01

    Nesse trabalho procurou-se identificar por meio de um questionário as concepções de Universo, de espaço e tempo que sustentam a visão de mundo de um grupo de 270 estudantes de Ensino Médio, pertencentes a três escolas de São Paulo. As questões relacionadas aos conhecimentos prévios dos estudantes permitiram constatar que há pouco conhecimento acerca dos temas investigados, destacando-se que apenas 20% dos alunos foram capazes de relacionar as semanas com as fases da lua, enquanto 28% associaram as estações do ano à inclinação do eixo de rotação da Terra e 23% tinham noções das distâncias entre objetos celestes próximos da Terra. Enquanto 56% conseguiram relacionar o Big Bang com a origem do Universo, verificou-se que 37% reconheciam ano-luz como unidade de distância e 60% concebiam o Sol como uma estrela. No que se refere às fontes de aquisição que proporcionaram esses conhecimentos, apesar de 60% dos alunos indicarem a escola como principal fonte dos conhecimentos de Ast! ronomia, verificou-se claramente que para a maioria dos alunos seus conceitos ainda são inadequados, havendo necessidade de aprimoramento da abordagem desses conteúdos, pois apesar de popular, a Astronomia ainda é veiculada de maneira pouco esclarecedora e com imprecisões. Nesse contexto, são discutidas algumas possíveis contribuições que podem ser dadas para o ensino de Astronomia pelo uso das ferramentas computacionais nas escolas.

  18. Experiências internacionais da aplicação de sistemas de apoio à decisão clínica em gastroenterologia

    PubMed Central

    Tenório, Josceli Maria; Hummel, Anderson Diniz; Sdepanian, Vera Lucia; Pisa, Ivan Torres; de Fátima Marin, Heimar

    2015-01-01

    Objetivo Descrever as experiências recentes com a aplicação de sistemas de apoio à decisão clínica em gastroenterologia, de forma a estabelecer o nível de desenvolvimento, testes e vantagens conferidas à prática médica com a introdução desses softwares. Métodos Foi realizada busca nas bases de dados PubMed, LILACS e ISI Web of Knowledge, utilizando termos relacionados à sistemas de apoio à decisão e à gastroenterogia, incluindo artigos originais publicados no período entre 2005 e 2010. Foram recuperadas 104 publicações, na busca inicial e, após a aplicação dos critérios de inclusão e exclusão, foram eleitos nove estudos para leitura do texto completo. Resultados Os sistemas de apoio à decisão clínica apresentam grande multiplicidade de problemas clínicos e investigação de doenças. Em 89% dos casos, são descritos modelos experimentais para o desenvolvimento de sistemas de apoio à decisão clínica. A descrição dos resultados obtidos por técnicas de inteligência artificial em 78% das publicações. Em dois dos estudos foram realizadas comparações com o médico e em apenas uma publicação um estudo controlado foi descrito, mostrando evidências de melhorias na prática médica. Conclusão Os estudos mostram potenciais benefícios dos sistemas de apoio à decisão clínica à prática médica, porém, estudos controlados em ambiente real devem ser realizados para comprovar esta perspectiva. PMID:26491625

  19. Windows of opportunities and technological innovation in the Brazilian pharmaceutical industry.

    PubMed

    Tigre, Paulo Bastos; Nascimento, Caio Victor Machado França do; Costa, Laís Silveira

    2016-11-03

    The Brazilian pharmaceutical industry is heavily dependent on external sources of inputs, capital, and technology. However, the emergence of technological opportunities and the development of biotechnology and the decline of the patent boom and resulting advances by generic drugs have opened windows of opportunities for the local industry. The article examines the Brazilian industry's innovative behavior vis-à-vis these opportunities, showing that although the industry as a whole invests little in innovation, a few large Brazilian companies have expanded their market share and stepped up their investments in research and development, supported by public policies for innovation. Resumo: A indústria farmacêutica brasileira caracteriza-se pela grande dependência de fontes externas de insumos, capital e tecnologia. O surgimento de oportunidades tecnológicas, associadas ao desenvolvimento da biotecnologia e ao fim do boom das patentes com o consequente avanço dos medicamentos genéricos, entretanto, vem abrindo janelas de oportunidades para a indústria local. Este artigo examina o comportamento inovador da indústria brasileira à luz dessas oportunidades, revelando que, embora o conjunto da indústria mantenha baixos níveis de investimentos em inovação, um pequeno grupo de grandes empresas nacionais vem ampliando sua participação no mercado e intensificando seus investimentos em pesquisa e desenvolvimento, apoiados por políticas públicas de inovação.

  20. Instruments used in the assessment of expectation toward a spine surgery: an integrative review.

    PubMed

    Nepomuceno, Eliane; Silveira, Renata Cristina de Campos Pereira; Dessotte, Carina Aparecida Marosti; Furuya, Rejane Kiyomi; Arantes, Eliana De Cássia; Cunha, Débora Cristine Prévide Teixeira da; Dantas, Rosana Aparecida Spadoti

    2016-01-01

    To identify and describe the instruments used to assess patients' expectations toward spine surgery. An integrative review was carried out in the databases PubMed, CINAHL, LILACS and PsycINFO. A total of 4,402 publications were identified, of which 25 met the selection criteria. Of the studies selected, only three used tools that had confirmed validity and reliability to be applied; in five studies, clinical scores were used, and were modified for the assessment of patients' expectations, and in 17 studies the researchers developed scales without an adequate description of the method used for their development and validation. The assessment of patients' expectations has been methodologically conducted in different ways. Until the completion of this integrative review, only two valid and reliable instruments had been used in three of the selected studies. Identificar e descrever os instrumentos usados para avaliar a expectativa dos pacientes diante do tratamento cirúrgico da coluna vertebral. Revisão Integrativa realizada nas bases de dados PubMed, CINAHL, LILACS e PsycINFO. Identificamos 4.402 publicações, das quais 25 atenderam aos critérios de seleção. Dos estudos selecionados, apenas em três os autores utilizaram instrumentos que possuíam validade e confiabilidade confirmadas para serem aplicados; em cinco estudos foram utilizados escores clínicos, modificados para a avaliação das expectativas dos pacientes, e em dezessete os pesquisadores elaboraram escalas sem adequada descrição do método usado para o seu desenvolvimento e validação. A avaliação das expectativas dos pacientes tem sido metodologicamente conduzida de diferentes maneiras. Até a finalização desta revisão integrativa, apenas dois instrumentos, válidos e confiáveis, haviam sido utilizados em três dos estudos selecionados.

  1. Spatial Distribution and Coexisting Patterns of Adults and Nymphs of Tibraca limbativentris (Hemiptera: Pentatomidae) in Paddy Rice Fields.

    PubMed

    Alves, Tavvs M; Maia, Aline H N; Barrigossi, José A F

    2016-12-01

    adultos e ninfas de T. limbativentris e determinar a coexistência espacial entre os estágios de desenvolvimento. As densidades de adultos e ninfas foram estimadas em quinze campos de arroz irrigado. A amostragem foi realizada em grades regulares com pontos de amostragem separados por ∼50 m. Moran's I e semivariogramas foram usados para determinar os padrões de distribuição espacial. A coexistência espacial foi explorada pela análise de processos pontuais. Foi observado que adultos e ninfas tiveram padrões contrastantes de distribuição espacial dentro do mesmo campo; no entanto, a frequência de agregação não foi diferente entre esses estágios de desenvolvimento. Adultos e ninfas estavam agregados em sete campos e distribuídos aleatoriamente nos outros oito campos. Não foi observada a distribuição uniforme de adultos ou ninfas. O alcance médio dos semivariogramas foi de ∼40 m para os adultos e ∼55 m para as ninfas. Ninfas e adultos coexistiram espacialmente em 67% dos campos. Os padrões de coexistência foram classificados usando um dos seguintes processos: independente do estágio de desenvolvimento, atração bilateral, atração unilateral, inibição bilateral, ou inibição unilateral. Nosso estudo poderá contribuir para o desenvolvimento de planos de amostragem para tomada de decisão e implementação de táticas para o manejo de sítios específicos. © The Authors 2016. Published by Oxford University Press on behalf of Entomological Society of America. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  2. Prevalence of auditory changes in newborns in a teaching hospital.

    PubMed

    Guimarães, Valeriana de Castro; Barbosa, Maria Alves

    2012-04-01

    Introdução: O diagnóstico e a intervenção precoces na surdez são de fundamental importância no desenvolvimento infantil. A perda auditiva e mais prevalente que outros distúrbios encontrados ao nascimento.Objetivo: Estimar a prevalência de alterações auditivas em recém-nascidos em um hospital escola.Método: Estudo transversal prospectivo que avaliou 226 recém-nascidos, nascidos em um hospital público, entre maio de 2008 a maio de 2009.Resultados: Dos 226 triados, 46 (20,4%) apresentaram ausência de emissões, sendo encaminhados para a segunda emissão. Das 26 (56,5%) crianças que compareceram no reteste, 8 (30,8%) permaneceram com ausência e foram encaminhadas ao otorrinolaringologista. Cinco (55,5%) compareceram e foram examinadas pelo médico. Destas, 3 (75,0%) apresentaram otoscopia normal, sendo encaminhadas para avaliação do Potencial Evocado Auditivo de Tronco Encefálico (PEATE). Do total de crianças estudadas, 198 (87,6%) tiveram presença de emissões em um dos testes e, 2 (0,9%) com diagnóstico de surdez.Conclusão: A prevalência de alterações auditivas na população estudada foi de 0,9%. O estudo oferece dados epidemiológicos relevantes e apresenta o primeiro relatório sobre o tema, fornecendo resultados preliminares para futura implantação e desenvolvimento de um programa de triagem auditiva neonatal.

  3. Malignant Small Bowel Tumors: Diagnosis, Management and Prognosis.

    PubMed

    Cardoso, Hélder; Rodrigues, João Tiago; Marques, Margarida; Ribeiro, Armando; Vilas-Boas, Filipe; Santos-Antunes, João; Rodrigues-Pinto, Eduardo; Silva, Marco; Maia, José Costa; Macedo, Guilherme

    2015-01-01

    Introdução: Apesar de entidades raras, a incidência dos tumores malignos do intestino delgado parece estar a aumentar. O desenvolvimento da cápsula endoscópica e da enteroscopia assistida por balão permitiram um avanço na avaliação das lesões do intestino delgado. Temos como objetivo descrever as características clínicas e patológicas dos doentes com cancro do intestino delgado e averiguar o papel que estas técnicas endoscópicas assumem atualmente. Material e Métodos: Foi realizado um estudo retrospetivo dos doentes diagnosticados com cancro do intestino delgado, desde janeiro de 2010 até outubro de 2014. Os dados foram submetidos a análise estatística. Resultados: Dos 28 doentes diagnosticados, 54% eram do sexo feminino. A idade média ao diagnóstico foi de 61 anos. O tumor mais frequente foi o adenocarcinoma (n = 11), seguido do sarcoma (n = 6), linfoma (n = 6) e tumores neuroendócrinos (n = 3). A principal forma de apresentação esteve relacionada com perdas hemáticas ou obstrução intestinal. Ao diagnóstico, 46% dos doentes tinhammetástases distantes/tumor irressecável. A maioria dos tumores foi diagnosticada por técnicas endoscópicas (41%) ou imagiológicas (35%). No primeiro ano após o diagnóstico, 29% dos doentes faleceram. Na análise multivariada, o adenocarcinoma permaneceu fator independente para pior sobrevida. Discussão: Os doentes com adenocarcinoma apresentaram-se em estádios tardios e com tumores irressecáveis, contribuindo para um pior prognóstico. Ã necessário um elevado grau de suspeita clínica para o diagnóstico de cancro do intestino delgado. Conclusão: As características dos doentes foram globalmente consistentes com o descrito na literatura. A cápsula endoscópica e a enteroscopia assistida por balão são úteis no diagnóstico, gestão e vigilância do cancro do intestino delgado.

  4. Contagem de fontes de radio na direção de aglomerados ricos de galaxias

    NASA Astrophysics Data System (ADS)

    Andreazza, C. M.; Andernach, H.

    A contagem de fontes de rádio, na direção de aglomerados ricos de galáxias, deve fornecer uma distribuçãto acima da média do campo devido aos efeitos do meio. No entanto, a distribução de radiofontes de alguns aglomerados, investigada por vários autores no passado, mostrou, em alguns casos, uma deficência de fontes fracas. Neste trabalho, analisamos os levantamentos em 2.7 GHz (Reuter e Andernach 1990, 1990A&AS...82..279R; Loiseau et al. 1988, 1988A&AS...75...67L) e o catálogo 6CII em 151 MHz (Hales et al. 1988, 1988MNRAS.234..919H). Nosso estudio da distribução de radiofontes, na direção de aglomerados ricos de galáxias, nestas duas frequências, mostra um excesso de fontes fortes somente nas regiões centrais dos aglomerados. Este resultado pode ser explicado devido à evidência de confinamento das radiofontes pelo gás, do meio intra-aglomerado, e devido aos processos de colisão, coalescência e canibalismo de galáxias.

  5. The development of communication skills and the teacher's performance in the nursing student's perspective.

    PubMed

    Oliveira, Karime Rodrigues Emilio de; Braga, Eliana Mara

    2016-06-01

    To understand experiences in the development of communication skills and the teacher's role in this teaching-learning process under the perspective of undergraduate nursing students by considering two types of curriculum organization. Descriptive study with a qualitative approach conducted in two public schools located in São Paulo state, Brazil. Data were collected by means of self-completed forms from 81 students in the second and fourth years of the undergraduate program. Results were analyzed in light of Content Analysis. Results showed that the development of such skills is related to: students' individual characteristics, patients' characteristics, those of the health-disease process, the health-care team's profile and the theoretical knowledge acquired on communication in health-care provision and nursing. The teacher's role was perceived as one that supports and encourages interactions with patients and health-care teams by teaching and providing orientation about interpersonal communication. Students identify and value the importance of their teachers' performance in the development and acquisition of communication skills. Additionally, students who experience active teaching-learning methodologies acknowledge the teacher as essential to provide opportunities for students to express their knowledge and thoughts. Compreender, sob a ótica de graduandos de enfermagem, as experiências no desenvolvimento de habilidades comunicativas e a atuação do professor neste processo de ensino-aprendizagem, considerando dois tipos de organização curricular. Pesquisa descritiva com abordagem qualitativa, realizada em duas instituições de ensino públicas, situadas no interior do estado de São Paulo, Brasil. A coleta dos dados foi realizada pelo autopreenchimento de formulário por 81 alunos de segundo e quartos anos da graduação. Os resultados foram analisados à luz da Análise de Conteúdo. Revelaram que o desenvolvimento desta habilidade está relacionado

  6. A Utilização da Astronomia como Tema Interdisciplinar e Aplicações de Objetos de Aprendizagem

    NASA Astrophysics Data System (ADS)

    da Silva, L. A.; Voelzke, M. R.

    2008-09-01

    Este trabalho visa analisar a possibilidade de relacionar conteúdos aplicados no ensino fundamental e médio de forma interdisciplinar por intermédio da astronomia, com a intervenção de objetos de aprendizagem que possam integrar as disciplinas e a utilização de recursos tecnológicos. Em uma pesquisa prévia com 20 professores de uma escola estadual situada na cidade de Guarulhos foi observado que apenas 25% dos professores utilizam algum recurso tecnológico para o desenvolvimento de conteúdos pertinentes à sua disciplina, tais como sites e softwares educativos, sendo que a maioria absoluta continua ensinando apenas com livros didáticos. A maior parte dos professores apresenta dificuldades em trabalhar sua disciplina de forma interdisciplinar, ou seja, 75% dos professores preferem aplicar os conteúdos seguindo uma hierarquia linear de tópicos, evitando a discussão de temas que de alguma forma estão relacionados. A astronomia pode vir à fascinar o ser humano e despertar sua curiosidade promovendo um maior interesse no aprendizado, podendo favorecer análises interdisciplinares de forma lógica e objetiva, desta forma colocar a astronomia como tema motivador interdisciplinar, pode ser relevante no que se refere ao distanciamento da fragmentação dos conteúdos. No Estado de São Paulo, a implantação da proposta curricular no ensino fundamental e médio mostra claramente a inserção da astronomia na maior parte das séries, principalmente na 6ª série em que todo o bimestre se fala de astronomia.

  7. [Deep brain stimulation: new frontier in the treatment of CNS disorders].

    PubMed

    Gonçalves Ferreira, Antonio

    2014-01-01

    Introdução: O autor faz uma revisão das indicações atuais da estimulação cerebral profunda, dos seus desenvolvimentos e resultados, dos alvos e técnicas utilizados, dos principais neurocirurgiões e centros médicos envolvidos.Material e Métodos: Esta revisão é baseada na experiência do grupo de Neurocirurgia Funcional do Hospital de Santa Maria (Centro Hospitalar Lisboa Norte) desde 1995 e na revisão bibliográfica dos artigos publicados sobre esta matéria desde 1980 indexados na PubMed.Resultados e Discussão: São apresentadas e discutidas as aplicações da estimulação cerebral profunda nos diferentes domínios das neurociências funcionais: Doenças do Movimento, incluindo doença de Parkinson, distonias e tremores, síndrome de Gilles de la Tourette, dor crónica, epilepsia e psicocirurgia nas múltiplas áreas que esta compreende: perturbação obsessiva-compulsiva, depressão grave refratária, comportamento disruptivo com agressividade intratável, deterioração da memória e demência, perturbações do comportamento alimentar (anorexia nervosa, obesidade mórbida) e toxicodependências refratárias (álcool, opioides, cocaína).Conclusões: Na maioria das situações clínicas referidas a estimulação cerebral profunda constitui um recurso terapêutico seguro e eficaz a ter em consideração quando as terapias habituais se mostram insuficientes; nos restantes casos há que reunir maior experiência até adotar o seu uso regular.

  8. Simulação de ejeções de massa coronal

    NASA Astrophysics Data System (ADS)

    Corsini, M. A.; Silva, A. V. R.

    2003-08-01

    Ejeções de massa coronal (EMC) são bolhas gigantes de gás permeadas por campos magnéticos que são ejetadas do Sol durante um período de várias horas. Caso estas ejeções atinjam a Terra, geralmente, causam uma série de distúrbios às comunicações de longa distância e navegação, além de danos a satélites e transformadores. Portanto, é desejável que sejamos capazes de prever quando estas ejeções atingirão a Terra. Para tanto, é necessário um bom entendimento dos mecanismos causadores das ejeções e, principalmente, de como se dá a propagação das EMC e sua interação com o vento solar que permeia o meio interplanetário. Nesse sentido foi desenvolvido um programa computacional para resolver as equações MHD (Magneto-Hidro-Dinâmica) que regem a evolução das EMC. Primeiramente foram estabelecidas as condições necessárias para descrever o vento solar, no estado estacionário, que permeia todo o meio interplanetário. Num primeiro momento, resolveu-se o sistema de equações para o caso do vento isotérmico, conhecida como a solução de Parker, a fim de testarmos o modelo. Então, foi considerado o caso do vento solar com temperatura variável no meio interplanetário. Este resultado foi utilizado como a base de nosso sistema em seu instante inicial. Posteriormente foram feitas as considerações necessárias para descrever a propagação da Ejeção de Massa Coronal. As EMC foram simuladas como um aumento de densidade e temperatura local na coroa solar. A órbita e a posição da Terra foram incluídas no sistema. Os dados gerados possibilitaram uma análise da evolução da EMC pelo meio interplanetário até encontrar-se com a Terra. Os perfis de densidade e temperatura a 1 Unidade Astronômica são comparados com os dados de satélites reportados na literatura.

  9. Adult Acne: Prevalence and Portrayal in Primary Healthcare Patients, in the Greater Porto Area, Portugal.

    PubMed

    Semedo, Diogo; Ladeiro, Filipa; Ruivo, Mariana; D'Oliveira, Carlos; De Sousa, Filipa; Gayo, Mariana; Lima, Clara; Magalhães, Frederico; Brandão, Rui; Branco, Maria; Da Silva, Isabel; Batista, Joana; Amado, João; Massa, António; Neves-Amado, João

    2016-09-01

    Introdução: A acne, apesar de caraterística no adolescente, afeta frequentemente o adulto. Em Portugal, não são conhecidos estudos sobre a prevalência da acne no adulto, nomeadamente observada nos grandes centros populacionais. Os objetivos deste estudo foram estimar a prevalência da acne nos utentes dos serviços de cuidados de saúde primários, as suas características, incluindo fatores de risco para início e/ou agravamento, além de coletar informação relacionada com a automedicação e/ou tratamento prescrito. Material e Métodos: Aplicação de questionário e exame físico a amostra composta por adultos entre os 20 - 60 anos de idade que visitaram, em dias aleatórios, cinco centros de saúde da área do Grande Porto. Resultados: Dos 1 055 adultos avaliados, a prevalência estimada de acne foi de 61,5%. Apenas 36,8% dos portadores estavam cientes da sua condição e somente 25% afirmou ter procurado tratamento. Mais de metade dos fumadores (62,3%) apresentavam acne. A zona mais afetada foi a região malar, diferindo da forma adolescente da doença. Discussão: A prevalência encontrada de acne foi mais elevada do que em outros estudos. A acne aparentou estar relacionada com a ingestão calórica aumentada, tabagismo, consumo de leite gordo ou meio gordo, hirsutismo, alopécia e seborreia. Conclusão: No contexto dos cuidados de saúde primários, mais de metade dos adultos eram portadores de acne. Estes números demonstram o quão importante pode ser a prevenção e intervenção pelos profissionais dos cuidados de saúde primários, tanto para a redução de eventuais factores de risco como para a intervenção terapêutica e consequências psicossociais relacionadas com a acne. Palavras-chave: Acne Vulgaris/epidemiologia; Adulto; Cuidados de Saúde Primários; Portugal; Prevalência.

  10. Ensino de astronomia e óptica: é possível fazê-lo de forma contextualizada no nível médio?

    NASA Astrophysics Data System (ADS)

    Sobrinho, A. A.; Jafelice, L. C.

    2003-08-01

    Discutimos nossa participação em um curso de treinamento para professores de diversas disciplinas do ensino médio. Nossa preocupação básica foi desenvolver instrumentos educacionais adequados para levar à sala de aula, nesse nível de ensino, de forma contextualizada, questionamentos freqüentes dos alunos sobre astronomia e sua relação com tecnologia e sociedade. Encaminhamos questões como: a evolução da astronomia, suas relações com outros ramos do conhecimento humano e conseqüentes aplicações; avanços na tecnologia dos instrumentos ópticos versus a importância da observação do céu a olho nu; a relação entre olho humano, luneta e telescópio; e desenvolvimento da tecnologia espacial e sua influência em nosso cotidiano. Objetivamos com isto fazer um resgate histórico e pedagógico das aplicações e observações do céu no cenário escolar, destacando a relação entre eventos astronômicos, olho humano, instrumentos mediadores e suas contextualizações históricas e sociais. Produtos desta abordagem foram o desenvolvimento e a adaptação de práticas e materiais instrucionais diversos (e.g., "espelhos" de isopor e "raios luminosos" de bolinhas de gude; montagens envolvendo velas, lasers, lentes e espelhos; desmonte e análise de peças de um telescópio; etc.). Além disto, como outro resultado deste trabalho, elaboramos textos sobre história da astronomia e da óptica para atividades em classe. Com estas ações visamos facilitar a concretização de conceitos físicos envolvidos, exemplificar um ensino contextualizado e interdisciplinar motivado por temas astronômicos e favorecer que práticas e discussões feitas com os treinandos possam ser transpostas para a sala de aula. A reação dos professores às práticas propostas foi bastante positiva. Todos esses aspectos são discutidos em detalhe neste trabalho. (PPGECNM/UFRN; PRONEX/FINEP; NUPA/USP; Temáticos/FAPESP)

  11. [Giardia duodenalis and chronic malnutrition in children under five from a rural area of Guinea-Bissau].

    PubMed

    Centeno-Lima, Sónia; Rosado-Marques, Vítor; Ferreira, Filipa; Rodrigues, Ruben; Indeque, Benjamim; Camará, Idrissa; De Sousa, Bruno; Aguiar, Pedro; Nunes, Baltazar; Ferrinho, Paulo

    2013-01-01

    Introdução: A desnutrição e as infecções por parasitas intestinais como Giardia duodenalis coexistem nas mesmas regiões geográficas, atingindo maiores prevalências em países em desenvolvimento. O ciclo da desnutrição e infecção implica que ambas as condições se podem agravar mutuamente e comprometer o crescimento e desenvolvimento das crianças, com especial relevância para as menores de cinco anos. O objectivo do presente estudo foi investigar a associação entre a desnutrição crónica e a infecção por G. duodenalis em crianças de uma comunidade rural da Guiné-Bissau.Material e Métodos: Realizou-se um estudo de caso-controlo que incluiu 109 crianças com idades entre os 0 e os 59 meses de uma comunidade rural da Guiné-Bissau. A avaliação antropométrica das crianças em estudo permitiu identificar 31 casos de desnutrição crónica (z-score estatura para a idade < -2) e 78 controlos (z-score estatura para a idade ≥ -2). Foi realizado exame microscópico de fezes para a detecção e identificação de G. duodenalis e de outros parasitas.Resultados: Foi detectada infecção por G. duodenalis em 29,0% (9/31) dos casos e 35,9% (28/78) dos controlos. Não foi encontrada associação entre a infecção por G. duodenalis e a desnutrição crónica nas crianças em estudo.Discussão e Conclusão: Os resultados obtidos mantêm em aberto o interesse em desenhar estudos que explorem esta associação em diferentes regiões e contextos epidemiológicos, apontando para a reflexão sobre a importância dos critérios de definição de desnutrição e concomitantemente da análise subsequente.

  12. Ensino de astronomia no 1o. e 2o. ciclos do nível fundamental e na educação de jovens e adultos: exemplos e discussões

    NASA Astrophysics Data System (ADS)

    Queiroz, A. S. B.; Jafelice, L. C.

    2003-08-01

    Tem-se constatado uma preocupante carência no ensino de astronomia nos diversos níveis de escolaridade. Neste trabalho discutimos várias práticas didático-pedagógicas que vimos desenvolvendo para crianças, jovens e adultos em processo de alfabetização, visando contribuir para reparar aquela carência. Propomos uma metodologia que incorpora as recentes exigências das políticas públicas educacionais, estimula o desenvolvimento de textos e materiais instrucionais, é compatível com a realidade desse público e é adaptável às respectivas faixas etárias. A observação do céu sempre esteve presente na vida de nossos antepassados, dando suporte à compreensão do ser humano como integrante da natureza. Visamos com este trabalho suprir a deficiência encontrada para se tratar a relação do ser humano com o céu, no ambiente escolar. Os resultados são animadores e envolvem práticas e textos que desenvolvemos e atividades realizadas pelos alunos. No primeiro grupo destacamos o desenvolvimento de várias práticas: "viagem aos planetas" (construímos o "foguete", os planetas em escala, contamos história e redigimos texto de orientação para os professores); "gnômon humano" (os próprios corpos dos alunos são usados para registrar o movimento aparente do Sol); "crateras da Lua" (concretização de "meteoritos" e "solo lunar" de gesso e exploração da relação entre energia cinética do bólido e tamanho da cratera formada); etc. No segundo grupo, produções de desenhos e redações e discussões dos alunos após a realização de cada prática, revelam que estas têm se mostrado muito eficientes, tanto para estimular a imaginação e a fantasia dos envolvidos, como para trabalhar-se habilidades, competências e conteúdos relacionados à astronomia, segundo uma perspectiva interdisciplinar contextualizada. (PPGECNM/UFRN; NUPA/USP; Temáticos/FAPESP)

  13. On Ensino da Astronomia no Ensino Médio sob Diferentes Abordagens Metodológicas

    NASA Astrophysics Data System (ADS)

    Voelzke, Marcos Rincon; Albrecht, Evonir

    2011-12-01

    O presente trabalho, sobre a intervenção de metodologias de ensino, foi desenvolvido na Escola Estadual Colônia dos Pescadores, na cidade de Caraguatatuba - SP, em três turmas do terceiro ano do Ensino Médio, perfazendo um total de 119 educandos, entre 16 e 19 anos. Antes de iniciar-se a intervenção, um questionário de vinte perguntas objetivas e dissertativas foi desenvolvido, aplicado pelo professor da classe, que ministrou as aulas correspondentes. Este questionário foi o mesmo em todas as três classes com o objetivo de diagnosticar o conhecimento prévio dos alunos sobre Astronomia. Começando a intervenção nas turmas, o professor envolvido usou três diferentes metodologias de ensino: (A) em forma de seminários, elaborados e apresentados pelos alunos, nos quais o professor fazia apenas as intervenções necessárias, (B) na forma tradicional, com a ajuda de multimídia para o desenvolvimento das aulas e a terceira (C) a tradicional, fazendo uso exclusivo de lousa e giz. No final do trabalho os alunos responderam o mesmo questionário novamente, de modo que os três métodos utilizados puderam ser comparados. Os resultados apresentados após a intervenção foram melhores que os resultados iniciais indicando a ocorrência de uma aprendizagem significativa. Quando os estudantes foram inicialmente questionados sobre quantos planetas existem no nosso sistema solar, a classe A obteve 39% de respostas certas, a classe B 48% e a classe C 46%, mas após o desenvolvimento das atividades, as classes obtiveram respectivamente 94%, 97 % e 90% de aproveitamento. No término do bimestre, foi sugerido aos educandos que elaborassem uma história em quadrinhos, a qual serviu para averiguar se os conceitos inicialmente observados foram alterados e se novos foram agregados. A análise das histórias foi dividida em três partes: Criatividade; Temas abordados; Emprego correto dos conceitos estudados. Ao final quatorze histórias foram confeccionadas. O aprendizado

  14. [Peritoneal Dialysis in the First Two Years of Life: Experience of a Nephrology and Renal Transplantation Pediatric Unit].

    PubMed

    Deuchande, Sofia; Mano, Tânia; Novais, Cristina; Machado, Rute; Stone, Rosário; Almeida, Margarida

    2016-09-01

    Introdução: A diálise peritoneal é o método dialítico de eleição perante doença renal crónica terminal em idade pediátrica. O objetivo deste estudo foi caracterizar a sobrevivência a longo prazo de uma população de crianças, que iniciou diálise peritoneal nos dois primeiros anos de vida. Material e Métodos: Estudo descritivo e retrospetivo, realizado numa unidade de nefrologia e transplantação renal pediátrica portuguesa, no período de janeiro de 1991 a agosto de 2014. Avaliou-se etiologia da doença renal crónica terminal, mortalidade, comorbilidades e complicações da diálise peritoneal e da doença renal crónica terminal, crescimento e desenvolvimento psicomotor.Resultados: Vinte crianças iniciaram diálise peritoneal antes dos dois anos. Ocorreram seis óbitos; não houve mortalidade em crianças com doença renal primária nos últimos 10 anos. Caracterizaram-se os 14 sobreviventes, 13 do sexo masculino. As anomalias congénitas do rim e do trato urinário constituíram a principal causa de doença renal crónica terminal (45%).O início de diálise peritoneal ocorreu em média aos 6,1 meses, em seis casos antes dos 30 dias de vida. A peritonite foi o motivo mais frequente de internamento. Dez crianças foram transplantadas, com idade média de 5,3 anos. Em relação ao crescimento, as quatro crianças que se mantêm em diálise peritoneal têm baixa estatura, mas nove dos transplantados têm uma estatura final dentro do esperado para a sua estatura-alvo familiar. Nove (64%) tiveram alterações no desenvolvimento psicomotor. Discussão: A diálise peritoneal é uma técnica possível e exequível desde o nascimento, tal como evidenciado nesta amostra, em que se iniciou com sucesso em mais de metade das crianças antes dos seis meses de vida. Permite uma sobrevivência a longo prazo até à possibilidade do transplante renal apesar da morbilidade associada, nomeadamente as peritonites e as complicações da doença renal

  15. Coping strategies of nurses in the care of patients with head and neck neoplasms.

    PubMed

    Santos, Naira Agostini Rodrigues Dos; Santos, Antonio Tadeu Cheriff Dos; Silva, Rildo Pereira da

    2016-01-01

    To understand and describe the experience of the development of coping strategies during the professional life of nurses providing care to patients with facial image alteration. Descriptive qualitative study with a hermeneutic-dialectic framework conducted in the head and neck ward of a reference hospital in Rio de Janeiro, with the participation of eight nurses and data produced through semi-structured interviews conducted between June and August 2013. Three major impressions were found: initial estrangement and complexity, consisting in the care given to patients with facial image alteration; a threshold between estrangement and coping, corresponding to the emergence of coping strategies during care; and image-likeness as a (re)cognition of the individual with facial image alteration in the development and consolidation of coping strategies during care. Among other contributions, the identification and understanding of coping strategies may contribute to better qualify nursing education and care. Compreender e descrever a experiência de desenvolvimento de estratégias de enfrentamento durante a vida profissional de enfermeiras no cuidado aos pacientes com imagem facial alterada. Pesquisa qualitativa descritiva, com referencial hermenêutico-dialético, realizada na Seção de Cabeça e Pescoço de um hospital de referência do Rio de Janeiro, com participação de oito enfermeiras e dados produzidos por meio de entrevista semiestruturada entre junho e agosto de 2013. Emergiram três amplos sentidos: estranhamento e complexidade iniciais, que constituem o cuidado ao paciente com imagem facial alterada; limiar entre estranhamento e enfrentamento, correspondendo à emersão das estratégias de enfrentamento durante o cuidado; e imagem-semelhança como (re)conhecimento da pessoa com imagem facial alterada no desenvolvimento e na consolidação das estratégias de enfrentamento durante o cuidado. Entre outras contribuições, a identificação e a compreensão das

  16. Building a world-wide open source community around a software framework: progress, dos, and don'ts

    NASA Astrophysics Data System (ADS)

    Ibsen, Jorge; Antognini, Jonathan; Avarias, Jorge; Caproni, Alessandro; Fuessling, Matthias; Gimenez, Guillermo; Verma, Khushbu; Mora, Matias; Schwarz, Joseph; Staig, Tomás.

    2016-08-01

    As we all know too well, building up a collaborative community around a software infrastructure is not easy. Besides recruiting enthusiasts to work as part of it, mostly for free, to succeed you also need to overcome a number of technical, sociological, and, to our surprise, some political hurdles. The ALMA Common Software (ACS) was developed at ESO and partner institutions over the course of more than 10 years. While it was mainly intended for the ALMA Observatory, it was early on thought as a generic distributed control framework. ACS has been periodically released to the public through an LGPL license, which encouraged around a dozen non-ALMA institutions to make use of ACS for both industrial and educational applications. In recent years, the Cherenkov Telescope Array and the LLAMA Observatory have also decided to adopt the framework for their own control systems. The aim of the "ACS Community" is to support independent initiatives in making use of the ACS framework and to further contribute to its development. The Community provides access to a growing network of volunteers eager to develop ACS in areas that are not necessarily in ALMA's interests, and/or were not within the original system scope. Current examples are: support for additional OS platforms, extension of supported hardware interfaces, a public code repository and a build farm. The ACS Community makes use of existing collaborations with Chilean and Brazilian universities, reaching out to promising engineers in the making. At the same time, projects actively using ACS have committed valuable resources to assist the Community's work. Well established training programs like the ACS Workshops are also being continued through the Community's work. This paper aims to give a detailed account of the ongoing (second) journey towards establishing a world-wide open source collaboration around ACS. The ACS Community is growing into a horizontal partnership across a decentralized and diversified group of actors, and we are excited about its technical and human potential.

  17. Full-screen ultrafast video modes over-clocked by simple VESA routines and registers reprogramming under MS-DOS.

    PubMed

    Liu, Zuxiang; Wang, Bo

    2002-05-01

    Fast full-screen presentation of stimuli is necessary in psychological research. Although Spitczok von Brisinski (1994) introduced a method that achieved ultrafast display by reprogramming the registers, he could not produce an acceptable full-screen display. In this report, the author introduces a new method combining VESA routine calling with registers reprogramming that can yield a display at 640 x 480 resolution, with a refresh rate of about 150 Hz.

  18. [Implementation of indigenous people's health policy in Angra dos Reis, Rio de Janeiro, Brazil: obstacles and prospects].

    PubMed

    Chaves, Maria de Betania Garcia; Cardoso, Andrey Moreira; Almeida, Celia

    2006-02-01

    This article discusses the Brazilian National Policy for Indigenous People's Health, formulated in the 1990s as part of the national Health Reform Movement and based on the creation (in 1999) of the Indigenous Healthcare Sub-System. Coordinated at the central government level under the administration of the National Health Foundation/Ministry of Health, the implementation of this sub-system required adaptations in the organization of health services systems at the local level, with the creation of Special Indigenous Health Districts. This configuration showed the need for dialogue and negotiation among the various institutions involved with indigenous affairs, from the perspective of overcoming various conflicts and operational difficulties. The current analysis identifies the difficulties in the implementation of a differentiated indigenous health policy under federal responsibility and within the decentralized Brazilian Unified Health System (SUS), since the absence of specific mechanisms and instruments regulating the operationalization of these services at the local level and the lack of more effective supervision and on-going evaluation of this policy mean that differentiated care for the indigenous population is subject to both the vices and virtues of local policy.

  19. GLOBAL CHANGE RESEARCH NEWS #9: ORD PROVIDES TECHNICAL SUPPORT TO EPA/OIA & DOS INITIATIVE IN EGYPT

    EPA Science Inventory

    This ninth edition reports on a workshop on global climate change that was held in Cairo, Egypt, on May 10-12, 1999. The workshop represented a successful partnership between EPA's Office of International Affairs, Office of Research and Development (ORD), Office of Air and Radiat...

  20. NGC 2849 y NGC 6134: dos cúmulos abiertos más para el proyecto BOCCE

    NASA Astrophysics Data System (ADS)

    Ahumada, A. V.; Bragaglia, A.; Cignoni, M.; Donati, P.; Tosi, M.; Marconi, G.

    The "Bologna Open Cluster Chemical Evolution" (BOCCE) project is a photometric and spectroscopic survey of Galactic open clusters (OCs), to be used as tracers of the properties and evolution of the Galactic disk. The main OCs parameters are derived in a precise and homogeneous way, and they will be used, for example, to determine the metallicity distribution in the Galactic disk and how it has evolved with time. We present here part of our last effort, concerning the photometric data obtained for NGC 2849 and NGC 6134. FULL TEXT IN SPANISH

  1. Cozinha: Um Lugar para a "bildung" dos Educadores (The Kitchen: A Place for the "bildung" of Educators).

    ERIC Educational Resources Information Center

    Damiano, Gilberto

    2000-01-01

    Uses a kitchen metaphor for philosophy of education, in dialogue with Augustine, Erasmus of Rotterdam, Brillat-Savarin, and others. Mixes and cooks ingredients in thinking: the centrality of the human being, corporeality, historicity, and transcendency; food as sign-symbol; eating-linguistic habits; educator-cook; space of the kitchen; sensuality,…

  2. Computer Aided Drafting Packages for Secondary Education. Edition 2. PC DOS Compatible Programs. A MicroSIFT Quarterly Report.

    ERIC Educational Resources Information Center

    Pollard, Jim

    This report reviews eight IBM-compatible software packages that are available to secondary schools to teach computer-aided drafting (CAD). Software packages to be considered were selected following reviews of CAD periodicals, computers in education periodicals, advertisements, and recommendations of teachers. The packages were then rated by…

  3. Protective Action Evaluator for Chemical Emergencies: A user's manual (MS-DOS reg sign Version 1. 0)

    SciTech Connect

    Rogers, G.O.; Sharp, R.D.

    1990-10-01

    The protective action evaluator for chemical emergencies (PAECE) is a package of computer programs developed to simulate an emergency response to airborne release of chemical agents. This user's manual documents the use of PAECE in the evaluation of chemical agent emergencies in areas potentially affected by the Chemical Stockpile Emergency Planning Program (CSEPP). This research documents the development and use of a method for the evaluation of protective action alternatives in conjunction with potential chemical agent emergencies. The user's manual highlights the development of the PAECE model, the selection of appropriate parameters to represent various scenarios, generate results and interpret them in the analysis of protective action alternatives during the planning and preparedness phases of the CSEPP. The PAECE model is designed to evaluate protective actions in the context of potential accidents, the emergency management systems required to implement protective actions, and the anticipated consequences for human receptors. The implications and uncertainties of the model are discussed to provide potential users with insight into the use, limitations, and uncertainties associated with evaluating the effectiveness of protective action alternatives. While PAECE represents a unique and powerful tool to evaluate protective actions, the user must exercise caution when interpreting the results to avoid misrepresentation. The expected value interpretation of the PAECE results biases the results toward extreme values. Hence, the PAECE results have to be interpreted in the context exposures similar to those represented by the unprotected exposure and the protection capacity that tend to be associated with people completing the implementation of the required actions later than and earlier than average, respectively. 16 refs., 24 figs., 1 tab. (JF)

  4. Turbo Pascal Implementation of a Distributed Processing Network of MS-DOS Microcomputers Connected in a Master-Slave Configuration

    DTIC Science & Technology

    1989-12-01

    sequence as recommended in the Xmcdem protocol. The Master operator can check for a "live" Slave by watching for the received NAK characters, displayed...04H <aJ> 05H * nak [ 15H <can. 18H 2. Transmission Medium Level Protocol Asynchronous, 8 data bits, no parity, one stop bit. The protocol imposes no...it does in the current implementations. b. Receive Program Considerations The receiver has a 10-second timeout. It sends a < nak > every time it times

  5. Buen Comienzo, Buen Futuro: El Bebe de Dos Meses (Healthy Start, Grow Smart: Your Two-Month-Old).

    ERIC Educational Resources Information Center

    Department of Education, Washington, DC.

    Distributed by the U.S. Departments of Agriculture, Education, and Health and Human Services, this Spanish-language pamphlet provides parents with information and advice about their infants in the second month of life. The pamphlet outlines typical infant behavior at 2 months of age, the need for regular visits to a physician, health insurance,…

  6. Cornell Produces a Video of Safety Dos and Don'ts for the YouTube Set

    ERIC Educational Resources Information Center

    Lipka, Sara

    2008-01-01

    Don't drink too much, download pirated files, light candles, or prop open doors. Warnings like those pervade the weighty work of admonition known as the student handbook. However, Allen J. Bova wonders, "Who ever reads that?" So Mr. Bova, director of risk management and insurance at Cornell University, tried to reach students with a…

  7. Hybrid Identity in Academic Writing: "Are There Two of Me?" (Identidad híbrida: "¿hay dos yo?")

    ERIC Educational Resources Information Center

    Crawford, Troy; Lengeling, Martha; Mora Pablo, Irasema; Heredia Ocampo, Rocío

    2014-01-01

    This paper explores the construction of identity in an academic learning environment in Central Mexico, and shows how identity may be linked to non-language factors such as emotions or family. These issues are associated with elements of hybrid identity. To analyze this we draw on language choice as a tool used for the construction of identity and…

  8. What You Ask for Is What You Get: Some Dos and Don'ts for Assigning Research Projects.

    ERIC Educational Resources Information Center

    Fink, Deborah

    1986-01-01

    Guidelines for developing effective research assignments were distributed to University of Colorado, Boulder, teaching assistants and faculty by the Instructional Services Librarian. Suggestions concerning what to do (i.e., clarify research objectives, schedule library presentation) and what not to do (i.e., limit research to particular index or…

  9. Evaluation of Migrant Education, Numero Dos, Title I-M Programs in the State of Oregon. September 1972 - August 1973.

    ERIC Educational Resources Information Center

    Moore, William G., Comp.; And Others

    The Migrant Education Section of the Oregon State Department of Education is responsible for providing educational and ancillary services to children of migrant agricultural workers. Title I, Elementary and Secondary Education Act (ESEA), provides payment to state educational agencies for assistance in educating migrant children. Funds provided by…

  10. 76 FR 58074 - 30-Day Notice of Proposed Information Collection: DS-7001 and DS-7005, DOS-Sponsored Academic...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-19

    ... information collection request to the Office of Management and Budget (OMB) for approval in accordance with... Collection. Originating Office: Bureau of Educational and Cultural Affairs, ECA/A/E/EUR. Form Number: DS-7001... to the Office of Management and Budget (OMB) for up to 30 days from September 19, 2011....

  11. Early effects of low dos 12C6+ ion or X-ray irradiation on human peripheral blood lymphocytes

    PubMed Central

    Chen, Yingtai; Li, Yumin; Zhang, Hong; Xie, Yi; Chen, Xuezhong; Ren, Jinyu; Zhang, Xiaowei; Zhu, Zijiang; Liu, Hongliang; Zhang, Yawei

    2009-01-01

    The aim of this study was to estimate the acute effects of low dose 12C6+ ions or X-ray radiation on human immune function. The human peripheral blood lymphocytes (HPBL) of seven healthy donors were exposed to 0.05Gy 12C6+ ions or X-ray radiation and cell responses were measured at 24 hours after exposure. The cytotoxic activities of HPBL were determined by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT); the percentages of T and NK cells subsets were detected by flow cytometry; mRNA expression of interleukin (IL)-2, tumor necrosis factor (TNF)-α and interferon (IFN)-γ were examined by real time quantitative RT-PCR (qRT-PCR); and these cytokines protein levels in supernatant of cultured cells were assayed by enzyme-linked immunosorbent assays (ELISA). The results showed that the cytotoxic activity of HPBL, mRNA expression of IL-2, IFN-γ and TNF-α in HPBL and their protein levels in supernatant were significantly increased at 24 hours after exposure to 0.05Gy 12C6+ ions radiation and the effects were stronger than observed for X-ray exposure. However, there was no significant change in the percentage of T and NK cells subsets of HPBL. These results suggested that 0.05Gy high linear energy transfer (LET) 12C6+ radiation was a more effective approach to host immune enhancement than that of low LET X-ray. We conclude that cytokines production might be used as sensitive indicators of acute response to LDI. PMID:20401163

  12. The DOS 1 neutron dosimetry experiment at the HB-4-A key 7 surveillance site on the HFIR pressure vessel

    SciTech Connect

    Farrell, K.; Kam, F.B.; Baldwin, C.A.

    1994-01-01

    A comprehensive neutron dosimetry experiment was made at one of the prime surveillance sites at the High Flux Isotope Reactor (HFIR) pressure vessel to aid radiation embrittlement studies of the vessel and to benchmark neutron transport calculations. The thermal neutron flux at the key 7, position 5 site was found, from measurements of radioactivation of four cobalt wires and four silver wires, to be 2.4 {times} 10{sup 12} n{center_dot}m{sup {minus}2}{center_dot}s{sup {minus}1}. The thermal flux derived from two helium accumulation monitors was 2.3 {times} 10{sup 12} n{center_dot}m{sup {minus}2}{center_dot}{sup {minus}1}. The thermal flux estimated by neutron transport calculations was 3.7 {times} 10{sup 12} n{center_dot}m{sup {minus}2}s{sup {minus}1}. The fast flux, >1 MeV, determined from two nickel activation wires, was 1.5 {times} 10{sup 12} n{center_dot}m{sup {minus}2}{center_dot}s{sup {minus}1}, in keeping with values obtained earlier from stainless steel surveillance monitors and with a computed value of 1.2 {times} 10{sup 13} n{center_dot}m{sup {minus}2}{center_dot}{sup {minus}1}. The fast fluxes given by two reaction-product-type monitors, neptunium-237 and beryllium, were 2.6 {times} 10{sup 13} n{center_dot}m{sup {minus}2}{center_dot}s {sup {minus}1} and 2.2 {times} 10{sup 13} n{center_dot}m{sup {minus}2}s{sup {minus}1}, respectively. Follow-up experiments indicate that these latter high values of fast flux are reproducible but are false; they are due to the creation of greater levels of reaction products by photonuclear events induced by an exceptionally high ratio of gamma flux to fast neutron flux at the vessel.

  13. PETROMAP: MS-DOS software package for quantitative processing of X-ray maps of zoned minerals

    NASA Astrophysics Data System (ADS)

    Cossio, Roberto; Borghi, Alessandro

    1998-10-01

    This paper shows an application of energy dispersive spectrometry (EDS) for digital acquisition of multi-element X-ray compositional maps of minerals in polished thin sections. A square matrix of n EDS spectra with known X, Y coordinates is collected, converted and exported to a personal computer. Each spectrum of the matrix is processed and the apparent concentration of each analyzed element is calculated by means of PETROMAP, a program written in Quick-Basic which applies a quantitative ZAF/FLS correction. The results of processing are comparable to the conventional quantitative microprobe analyses, with similar counting statistics. The output is a numerical matrix, compatible with the most popular graphic and spreadsheet programs from which it is possible to produce two-dimensional wt% oxide, mole fractions and mineral end-members pseudocolored or black/white maps. The procedure has been tested using a metamorphic garnet of the medium-grade Stilo unit (Calabrian Arc, Southern Italy).

  14. Cornell Produces a Video of Safety Dos and Don'ts for the YouTube Set

    ERIC Educational Resources Information Center

    Lipka, Sara

    2008-01-01

    Don't drink too much, download pirated files, light candles, or prop open doors. Warnings like those pervade the weighty work of admonition known as the student handbook. However, Allen J. Bova wonders, "Who ever reads that?" So Mr. Bova, director of risk management and insurance at Cornell University, tried to reach students with a…

  15. First approach to studies of sulphur electron DOS in prostate cancer cell lines and tissues studied by XANES

    NASA Astrophysics Data System (ADS)

    Kwiatek, Wojciech M.; Czapla, Joanna; Podgórczyk, Magdalena; Kisiel, Andrzej; Konior, Jerzy; Balerna, Antonella

    2011-10-01

    Urological cancers comprise approximately one-third of all cancers diagnosed in men worldwide and out of these, prostate cancer is the most common one ( WHO World Cancer Report, 2008). Several risk factors such as age, hormone levels, environmental conditions and family history are suspected to play a role in the onset of this disease of otherwise obscure aetiology. It is therefore the medical need that drives multidisciplinary research in this field, carried out by means of various experimental and theoretical techniques. Out of many relevant factors, it is believed that sulphur can take an important part in cancer transformations. We have investigated the prostate cancer cell lines and tissues, along with selected organic and inorganic compounds used as references, by the X-ray absorption fine structure spectroscopy near the sulphur edge energy region. Particularly, the comparison of the experimental results collected during XANES measurements and theoretical calculations of electron density of states with use of the FEFF8 code and LAPW (linearised augmented plane-wave) method has been performed and in this work the first results of our studies are presented.

  16. GLOBAL CHANGE RESEARCH NEWS #9: ORD PROVIDES TECHNICAL SUPPORT TO EPA/OIA & DOS INITIATIVE IN EGYPT

    EPA Science Inventory

    This ninth edition reports on a workshop on global climate change that was held in Cairo, Egypt, on May 10-12, 1999. The workshop represented a successful partnership between EPA's Office of International Affairs, Office of Research and Development (ORD), Office of Air and Radiat...

  17. [Dos and don'ts for crystalloids in intensive care medicine. Can too much water be bad?].

    PubMed

    Wildenauer, R

    2015-04-01

    Notwithstanding the use of colloids, crystalloids have a firm position in today's intensive care: In addition to the substitution as a basic requirement of the human organism or drug carriers, they are primarily used for volume replacement. A common complication is the development of interstitial edema, which is due to the composition of these solutions and the permeability of the glycocalyx.With the large variety available on the market, bicarbonate-based precursor isotonic-balanced full electrolyte solutions have become established in the meantime. The use of 0.9% saline solution is regarded as obsolete. With low cost and a good safety profile, a few relevant aspects, e.g., the risk of hypervolemia and electrolyte imbalance, must be taken into account in the use of crystalloids.

  18. Reviewing three dimensional dosimetry: basics and utilization as presented over 17 Years of DosGel and IC3Ddose

    NASA Astrophysics Data System (ADS)

    Schreiner, L. J.

    2017-05-01

    For seventeen years a community of basic and clinical scientists and researchers has been meeting bi-annually to promote the clinical advance of techniques to measure radiation dose in three dimensions. The interest in this dosimetry was motivated by its promise as an effective methodology for 3D measurement of the complex conformal dose distributions achieved by modern techniques such as Intensity Modulated and Volumetric Arc Radiation Therapy. Each of the International Conferences on 3D Radiation Dosimetry resulted in the publication of informative proceedings [1-8], the majority openly available on the internet. The proceedings included papers that: i) reviewed the basic science of the radiation sensitive materials used to accumulate the dose information, ii) introduced the science and engineering of the imaging systems required to read the information out, iii) described the work flows and systems required for efficient dosimetry, iv) reported the protocols required for reproducible dosimetry, and v) showed examples of clinical use illustrating advantage and limitations of the dosimetry. This paper is intended to use the framework provided by these proceedings to review the current 3D chemical dosimeters available and to discuss the requirements for their use. The paper describes how 3D dosimetry can complement other dose delivery validation approaches available in the clinic. It closes with some personal reflections of how the motivation for, and practice of, 3D dosimetry have changed (or not) over the years.

  19. Evaluation of PTW Seven29 for tomotherapy patient-specific quality assurance and comparison with ScandiDos Delta(4).

    PubMed

    Myers, Pamela; Stathakis, Sotirios; Gutiérrez, Alonso N; Esquivel, Carlos; Mavroidis, Panayiotis; Papanikolaou, Niko

    2012-04-01

    For routine quality assurance of helical tomotherapy plans, an alternative method, as opposed to the TomoTherapy suggested cylindrical solid water phantom with film and ionization chamber, is proposed using the PTW Seven29 2D-ARRAY inserted in a dedicated octagonal phantom, called Octavius. First, the sensitivity of the array to pitch was studied by varying the pitch during planning to 0.287, 0.433, 1.0, and 2.0. For each pitch selected, the dependence on field size was investigated by generating plans with field widths (FWs) of 1.06 cm, 2.49 cm, and 5.02 cm, for a total of 12 plans. Secondly, a total of 15 patient QA plans were delivered using helical tomotherapy with the Delta(4) and Seven29/Octavius for comparison. Using the clinical gamma criteria, 3% and 3 mm, all FW and pitch plans had a passing percentage of >90%. For patient QA plans, the average gamma pass percentage was 97.0% (94.4-99.8%) for the Delta(4) and 97.6% (92.5-100.0%) for the Seven29/Octavius. Both the Seven29/Octavius and Delta(4) performed to a high standard of measurement accuracy and had a 90% or greater gamma percent for all plans and were considered clinically acceptable.

  20. Evaluation of PTW Seven29 for tomotherapy patient-specific quality assurance and comparison with ScandiDos Delta4

    PubMed Central

    Myers, Pamela; Stathakis, Sotirios; Gutiérrez, Alonso N.; Esquivel, Carlos; Mavroidis, Panayiotis; Papanikolaou, Niko

    2012-01-01

    For routine quality assurance of helical tomotherapy plans, an alternative method, as opposed to the TomoTherapy suggested cylindrical solid water phantom with film and ionization chamber, is proposed using the PTW Seven29 2D-ARRAY inserted in a dedicated octagonal phantom, called Octavius. First, the sensitivity of the array to pitch was studied by varying the pitch during planning to 0.287, 0.433, 1.0, and 2.0. For each pitch selected, the dependence on field size was investigated by generating plans with field widths (FWs) of 1.06 cm, 2.49 cm, and 5.02 cm, for a total of 12 plans. Secondly, a total of 15 patient QA plans were delivered using helical tomotherapy with the Delta4 and Seven29/Octavius for comparison. Using the clinical gamma criteria, 3% and 3 mm, all FW and pitch plans had a passing percentage of >90%. For patient QA plans, the average gamma pass percentage was 97.0% (94.4–99.8%) for the Delta4 and 97.6% (92.5-100.0%) for the Seven29/Octavius. Both the Seven29/Octavius and Delta4 performed to a high standard of measurement accuracy and had a 90% or greater gamma percent for all plans and were considered clinically acceptable. PMID:22557796

  1. A new generation of real-time DOS technology for mission-oriented system integration and operation

    NASA Technical Reports Server (NTRS)

    Jensen, E. Douglas

    1988-01-01

    Information is given on system integration and operation (SIO) requirements and a new generation of technical approaches for SIO. Real-time, distribution, survivability, and adaptability requirements and technical approaches are covered. An Alpha operating system program management overview is outlined.

  2. Fotometría CCD de dos cúmulos abiertos con estrellas WR: NGC 6231 y TR 27

    NASA Astrophysics Data System (ADS)

    Baume, G.; Vázquez, R. A.; Feinstein, A.

    Se ha realizado fotometría CCD en los filtros UBVI del sistema de Cousins en las zonas de los cúmulos abiertos NGC 6231 y Trumpler 27, llegando hasta aproximadamente magnitud V=19. Ambos objetos presentan estrellas WR en su proximidad. Se ha re-determinado el Eb-v en esas direcciones, asi como la distancia a la que se encontrarían los cúmulos y sus edades por medio de un ajuste de la ZAMS y de un conjunto de isocronas respectivamente.

  3. The Dos and Don'ts of how to Build a Planet, Using the Moon as an Example

    NASA Technical Reports Server (NTRS)

    Jones, J. H.

    2006-01-01

    The bulk chemical compositions of planets may yield important clues concerning planetary origins. Failing that, bulk compositions are still important, in that they constrain calculation of planetary mineralogies and also constrain the petrogenesis of basaltic magmas. In the case of the Earth, there is little or no debate about the composition of the Earth's upper mantle. This is because our sample collections contain peridotitic xenoliths of that mantle. The most fertile of these are believed to have been little modified from their primary compositions. Using these samples and chondritic meteorites as a starting point, small perturbations on the compositions of existing samples allow useful reconstruction of the bulk silicate Earth (BSE). Elsewhere, I have argued that the next simplest case is the Eucrite Parent Body (EPB). Reconstructions based on Sc partitioning indicate that the EPB can be well approximated by a mixture of 20% eucrite and 80% equilibrium olivine. This leads to a parent body that is similar to CO (or devolatilized CM) chondrites. Partial melting experiments on CM chondrites confirm this model, because the residual solids in these experiments are dominated by olivine with minor pigonite [3]. The most difficult bodies to reconstruct are those that have undergone the most differentiation. Both the Moon and Mars may have passed through a magma ocean stage. In any event, lunar and martian basalts, unlike eucrites, were not derived from undifferentiated source regions. Reconstructions are primarily based on compositional trends within the basalts themselves with some critical assumptions: (i) Refractory lithophile elements (Ca, Al, REE, actinides) are presumed to be in chondritic relative abundances; and (ii) some major element ratio is believed to exist in a chondritic ratio (e.g., Mg/Si, Mg/Al). The most commonly used parameter is Mg/Si.

  4. Projeto do sistema anti-ressonante da fiação dos transdutores para o detector Mario Schenberg

    NASA Astrophysics Data System (ADS)

    Vieira, S. J.., Jr.; Melo, J. L.

    2003-08-01

    O detector de ondas gravitacionais Mario Schenberg está sendo projetado e construído pelo grupo Gráviton. Sua construção está ocorrendo no Laboratório de Estado Sólido e Baixas Temperaturas (LESBT) da Universidade de São Paulo, na cidade de São Paulo. Esse detector possui uma massa ressonante esférica de cobre-alumínio, com 65 cm de diâmetro, pesando aproximadamente 1150 Kg, suspensa por um sistema de isolamento vibracional, que se encontra em fase de testes preliminares. A real eficácia desse sistema, entretanto, só poderá ser comprovada quando o detector estiver aparelhado com, pelo menos, um transdutor eletromecânico de altíssima sensibilidade acoplado à massa ressonante. Neste momento, não só este sistema de isolamento vibracional será posto em teste, como o do projeto da fiação que transporta os sinais de microondas até os transdutores e destes para a pré-amplificação. Apesar dessa fiação ter sido projetada para não apresentar nenhum contato com a superfície esférica da antena, de maneira a não haver nenhuma transmissão de ruído vibracional do laboratório para esta, deve-se minimizar o ruído microfônico produzido nessa fiação por oscilações mecânicas, uma vez que ela não utiliza nenhum sistema de isolamento vibracional. Com o intuito de resolver este problema, projetamos uma estrutura, formada por pequenos cilindros conectados por barras, a qual não terá nenhuma ressonância mecânica na faixa de freqüências de interesse para detecção (3000 - 3400 Hz). Desta forma, as vibrações nessa faixa não serão amplificadas. O projeto foi feito usando iterativamente, de maneira a otimizar os resultados obtidos, o programa de elementos finitos Msc/Nastran. Através de simulações feitas neste programa, determinamos os parâmetros geométricos ideais a serem utilizados, os quais proporcionam a maior região espectral de interesse livre de ressonâncias.

  5. Programa Estrategico do desenvolvimento 1968-70: Area Estrategica IX. Infra-estructura Social. Educacao e Recursos Humanos, 1 e 2 (Strategic Development Program 1968-1970: Strategic Area IX. Education and Human Resources, Volumes 1 & 2).

    ERIC Educational Resources Information Center

    Brazil.

    This document is an English-language abstract (approximately 1,500 words) of a two volume work dealing with education and human resources as part of the Brazilian Government's Strategic Development Program 1968-70. It offers an integral view of education as an instrument of social transformation and an exposition of the quantitative and…

  6. Programa Estrategico do desenvolvimento 1968-70: Area Estrategica IX. Infra-estructura Social. Educacao e Recursos Humanos, 1 e 2 (Strategic Development Program 1968-1970: Strategic Area IX. Education and Human Resources, Volumes 1 & 2).

    ERIC Educational Resources Information Center

    Brazil.

    This document is an English-language abstract (approximately 1,500 words) of a two volume work dealing with education and human resources as part of the Brazilian Government's Strategic Development Program 1968-70. It offers an integral view of education as an instrument of social transformation and an exposition of the quantitative and…

  7. [Carotid atherosclerosis and white matter hypodensities: a controversial relationship].

    PubMed

    Félix-Morais, Ricardo; Sargento-Freitas, João; Silva, Fernando; Cordeiro, Gustavo; Nunes, César; Ribeiro, Joana; Cordeiro, Miguel; Moura, Cristina; Cunha, Luis

    2014-01-01

    Introdução: As hipodensidades da substância branca de provável etiologia vascular, são uma causa importante de morbilidade, condicionando deterioração cognitiva. No entanto, numerosas dúvidas persistem quanto à sua fisiopatologia. O objectivo deste estudo é clarificar o papel da aterosclerose carotídea e outros factores de risco vascular no desenvolvimento das hipodensidades da substância branca de provável etiologia vascular.Material e Métodos: Realizou-se uma avaliação imagiológica, por tomografia computadorizada crânio-encefálica e ecografia carotídea, com menos de um mês de intervalo. Procedeu-se à recolha de informação sobre os factores de risco vascular. Determinámos associações independentes entre hipodensidades da substância branca de provável etiologia vascular, espessura da íntima média carotídea, estenose carotídea ateromatosa e factores de risco vascular.Resultados: Foram incluídos 472 doentes, idade média de 67,32 (DP: 14.75), 274 (58,1%) sexo masculino. Os preditores independentes da hipodensidades da substância branca de provável etiologia vascular foram: idade (OR: 1,067, 95% IC: 1,049 – 1,086, p < 0,001) e a hipertensão (OR: 1,726, 95% IC: 1,097 – 2,715, p = 0,018). Não foi encontrada uma associação entre a espessura da intima média carotídea (OR: 2,613, 95% IC: 0,886 – 7,708, p = 0,082) ou grau de estenose carotídea (OR: 1,021, 95% IC: 0,785 – 1,328, p = 0,877) e hipodensidades da substância branca de provável etiologia vascular.Discussão: Dos diversos factores de risco analisados, apenas a idade e hipertensão se associaram de forma independente às hipodensidades da substância branca de provável etiologia vascular. Não foi encontrada uma relação entre a aterosclerose extracraniana, expressa pela espessura do complexo intima-média ou grau de estenose, com o desenvolvimento de hipodensidades da substância branca de provável etiologia vascular. Sendo a aterosclerose um fen

  8. Effectiveness of teaching strategies on the development of critical thinking in undergraduate nursing students: a meta-analysis.

    PubMed

    Oliveira, Larissa Bertacchini de; Díaz, Leidy Johanna Rueda; Carbogim, Fábio da Costa; Rodrigues, Adriano Rogério Baldacin; Püschel, Vilanice Alves de Araújo

    2016-04-01

    To evaluate the effectiveness of teaching strategies used for development of critical thinking (CT) in undergraduate nursing students. Systematic review with meta-analysis based on the recommendations of the Joanna Briggs Institute . Searches were conducted in the following databases: PubMed, CINAHL, EMBASE, Web of Science, SCOPUS, LILACS, Cochrane CENTRAL, PsycINFO, ERIC, and a database of theses from four continents. The initial selection and evaluation of studies and assessment of methodological quality was performed by two reviewers independently. Twelve randomized clinical trials were included in the study. In the meta-analysis of the four studies included that evaluated the strategy of problem-based learning (PBL), compared to lectures, the effectiveness of PBL was demonstrated with statistical significance (SMD = 0.21 and 95% CI = 0.01 to 0.42; p = 0.0434) for the development of CT in undergraduate nursing students, and the studies were homogeneous (chi-square = 6.10, p = 0.106). The effectiveness of PBL was demonstrated in the increase of overall CT scores. Further studies need to be conducted in order to develop, implement and evaluate teaching strategies that are guided in high methodological rigor, and supported in theoretical models of teaching and learning. Avaliar a efetividade das estratégias de ensino utilizadas para o desenvolvimento do pensamento crítico (PC) em estudantes de graduação em Enfermagem. Revisão sistemática com metanálise baseada nas recomendações do Joanna Briggs Institute. A busca foi realizada nas bases de dados PubMed, CINAHL, EMBASE, Web of Science, SCOPUS, LILACS, Cochrane CENTRAL, PsycINFO e ERIC e de banco de teses dos quatro continentes. A seleção e avaliação inicial dos estudos e a avaliação da qualidade metodológica foi realizada por dois revisores de forma independente. Incluídos 12 ensaios clínico randomizados. Na metanálise, dos quatro estudos incluídos que avaliaram a estratégia do Problem Based

  9. Education Through Aerospace Components. (Spanish Title: Educación Através de Elementos Aeroespaciales.) Educação Através de Elementos Aeroespaciais

    NASA Astrophysics Data System (ADS)

    Barbosa Loureda, Oswaldo; Sobral de Araújo, Jéssyca B.

    2008-12-01

    tal, dispõe-se de diversos métodos e meios que vêm implantar idéias em prol do avanço do povo brasileiro nos aspectos pedagógicos, psicológicos e culturais. Alfabetizar é um ato que exige muito cuidado e responsabilidade; o comportamento e desempenho de um indivíduo na sociedade é resultado da maneira com que ele foi instruído. Contudo, a área de exatas exige especial atenção, pois os conhecimentos adquiridos são imprescindíveis para o desenvolvimento pessoal do individuo, assim como para o futuro tecnológico do País. Como meio alternativo ou complementar de ensino é sugerido o uso de elementos aeroespaciais, devido ao fato de comportar uma vasta quantidade e qualidade de disciplinas envolvidas respectivamente com competências de grande importância para sua vida profissional futura. Uma nova Corrida acontece, porém dessa vez a meta não é a Lua e sim o conhecimento.

  10. Elderly with knee osteoarthritis should perform nutritional assessment: integrative literature review.

    PubMed

    Souza, Isabelle Ferreira da Silva; Oliveira Neta, Rosa Sá de; Gazzola, Juliana Maria; Souza, Marcelo Cardoso de

    2017-01-01

    To review scientific literature to assess nutritional status of elderly patients with osteoarthritis in the last 16 years. This is an integrative literature review that included articles published in national and international journals indexed in PubMed, SciELO and BIREME. We selected 14 articles, and English language was predominant. The year of publication of articles ranged from 2006 to 2016, and most of papers were cross-sectional studies. To gather papers and for posterior evaluate, we used a validated data collection instrument and the included studies were critical analyzed by reading, gathering and analysis of articles. Studies suggested that there is a positive correlation between obesity and knee osteoarthritis. Obesity is one of the most important modifiable factors in worsening of osteoarthritis symptoms. RESUMO O objetivo da pesquisa foi revisar a produção científica referente à avaliação do estado nutricional de idosos com osteoartrite nos últimos 16 anos. Assim, o estudo foi uma revisão integrativa da literatura, realizada com a busca de artigos publicados em periódicos nacionais e internacionais indexados no PubMed, na SciELO e na BIREME. Foram selecionados 14 artigos, e o idioma inglês foi preponderante. O período de publicação dos artigos variou de 2006 a 2016, com predominância de estudos do tipo transversais. Para reunir os artigos e para posterior avaliação, foi utilizado um instrumento de coleta de dados validado, e as análises críticas dos estudos incluídos foram realizadas por meio da leitura, do agrupamento e da análise dos artigos. As pesquisas sugeriram que existe correlação positiva entre obesidade e osteoartrite de joelhos. Além disto, a obesidade é um dos fatores mais significativos e modificáveis no agravamento dos sintomas da osteoartrite.

  11. Análise sobre o Conhecimento de um Grupo de Alunos do Ensino Médio da Rede Estadual de São Paulo sobre Termos e Fenômenos Astronômicos do Cotidiano

    NASA Astrophysics Data System (ADS)

    de Oliveira, E. F.; Voelzke, M. R.; Amaral, L. H.

    2007-08-01

    Embora os Parâmetros Curriculares Nacionais do Ensino Médio (PCN-EM) e as orientações complementares a esses Parâmetros (PCN+) apontem a importância de uma abordagem significativa de conceitos relacionados à astronomia nas aulas de Física, muitos estudantes terminam o Ensino Médio (EM) sem compreender a razão de certos acontecimentos de origem celeste, ainda que estes façam parte de seu cotidiano. Este trabalho tem por objetivo analisar os conhecimentos básicos em astronomia dos alunos de EM da escola estadual Batista Renzi, bem como investigar os meios através dos quais estes conhecimentos foram adquiridos. Para tanto foi elaborado um questionário de múltipla escolha aplicado a 310 alunos distribuídos entre as três séries do EM dos períodos matutino e noturno. Dessa forma, observou-se que apenas 34,5% relacionaram as estações do ano à inclinação do eixo de rotação da Terra, 21,3% indicaram a influência gravitacional da Lua e do Sol como responsáveis pelo fenômeno das marés, 24,5% indicaram corretamente quais são os objetos celestes mais próximos da Terra, 36,1% identificaram ano-luz como uma medida de distância e 34,2% reconheceram uma estrela cadente como meteoro. Em contrapartida, 67,1% compreendiam a sucessão entre dia e noite, 73,9% identificaram o Sol como estrela e 52,3% relacionaram o Big Bang à origem do Universo. Além disso, foram comparadas as respostas de alunos de diferentes séries e períodos, observando-se, dentre outras coisas, que os estudantes do terceiro ano apresentam um percentual de acertos semelhante ao dos alunos do primeiro, caracterizando que a abordagem de tópicos relacionados à astronomia no EM não tem contribuído para uma maior compreensão dos fenômenos e conceitos.

  12. PNAUM: integrated approach to Pharmaceutical Services, Science, Technology and Innovation.

    PubMed

    Gadelha, Carlos Augusto Grabois; Costa, Karen Sarmento; Nascimento, José Miguel do; Soeiro, Orlando Mário; Mengue, Sotero Serrate; Motta, Márcia Luz da; Carvalho, Antônio Carlos Campos de

    2016-12-01

    This paper describes the development process of the Pesquisa Nacional sobre Acesso, Utilização e Promoção do Uso Racional de Medicamentos (PNAUM - National Survey on Access, Use and Promotion of Rational Use of Medicines) based on an integrated approach to pharmaceutical services, science, technology and innovation. It starts by contextualizing health and development in Brazil and features elements of the National Policy for Science, Technology and Innovation in Health in Brazil and the National Policy for Pharmaceutical Services. On presenting pharmaceutical policy guidelines, it stresses the lack of nationwide data. This survey, commissioned by the Brazilian Ministry of Health, has two components: household survey and evaluation of pharmaceutical services in primary care. The findings point to perspectives that represent, besides the enhancement of public policy for pharmaceutical services and public health, results of government action aimed at developing the economic and industrial health care complex to improve the health conditions of the Brazilian population. RESUMO O artigo apresenta o processo de construção da Pesquisa Nacional sobre Acesso, Utilização e Promoção do Uso Racional de Medicamento a partir de uma concepção integradora da Assistência Farmacêutica, Ciência, Tecnologia e Inovação. Inicia-se contextualizando a saúde e o desenvolvimento no País e apresenta elementos da Política Nacional de Ciência Tecnologia e Inovação em Saúde no Brasil e da Política Nacional de Assistência Farmacêutica. Ao apresentar as diretrizes das Políticas Farmacêuticas, destaca-se a carência de dados de abrangência nacional. A presente pesquisa, encomendada pelo Ministério da Saúde, foi estruturada em dois componentes: inquérito domiciliar e avaliação dos serviços de assistência farmacêutica na atenção básica. As perspectivas dos resultados representam, além do incremento das políticas públicas farmacêuticas e de saúde p

  13. Developing skills learning in obstetric nursing: approaches between theory and practice.

    PubMed

    Lima, Maria de Fátima Gomes; Pequeno, Alice Maria Correia; Rodrigues, Dafne Paiva; Carneiro, Cleide; Morais, Ana Patrícia Pereira; Negreiros, Francisca Diana da Silva

    2017-01-01

    To analyze the development of professional skills in an obstetric nursing graduate course. Qualitative research, applying semi-structured interviews with 11 students in the obstetric nursing specialization at the State University of Ceará. Data was submitted to thematic review. According to the subjects, the course offers the development of skills to strengthen and expand the range of activities in obstetric nursing. Despite relying on previous knowledge and experience acquired by the students, there is a gap between the content taught and internship practice, presented as challenges and difficulties faced by the students. The findings suggest a need for curricular revision, incorporating active teaching-learning methodologies, to overcome the disjunction between theory and practice. Students are part of a corpus that is potentially implicated in the construction and transformation of thoughts and values set forth by educational and health institutions, and it is necessary to make changes in political and social organizations, with a focus on providing comprehensive and egalitarian care to the population. Analisar o desenvolvimento de competências profissionais em curso de pós-graduação em Enfermagem Obstétrica. Pesquisa qualitativa, utilizando entrevista semiestruturada com 11 egressos da especialização em Enfermagem Obstétrica da Universidade Estadual do Ceará. Dados submetidos à análise temática. Na ótica dos sujeitos, o curso confere o desenvolvimento de competências que fortalecem e ampliam o campo de atuação da enfermagem obstétrica. Embora resgate o conhecimento prévio dos discentes e as experiências vivenciadas, há distanciamento entre conteúdos ministrados e a prática de estágios, apresentados como desafios e dificuldades enfrentadas pelos egressos. Os achados sugerem revisão curricular, incorporando as metodologias ativas de ensino-aprendizagem, superando a fragmentação entre teoria e prática. Os egressos se constituem em um

  14. Incorporando a variabilidade no processo de identificação do modelo de máximo global no Grade of Membership (GoM): considerações metodológicas

    PubMed Central

    Guedes, Gilvan Ramalho; Siviero, Pamila Cristina Lima; Caetano, André Junqueira; Machado, Carla Jorge; Brondízio, Eduardo

    2012-01-01

    A disponibilidade de bases de dados cada vez mais complexas e multidimensionais é um dos principais motivadores para o aumento do número de estudos que utilizam análises multivariadas baseadas em lógica de conjuntos nebulosos. Apesar da disseminação do método Grade of Membership nos trabalhos empíricos brasileiros da área de ciências sociais e saúde, questões relativas à identificabilidade e estabilidade dos parâmetros finais estimados pelo programa GoM 3.4 não foram suficientemente aprofundadas. Dada a relevância de se obterem parâmetros únicos e estáveis, Guedes et al. (2010) propuseram um procedimento empírico para localizar um modelo de máximo global (MG) com parâmetros estáveis. Entretanto, seu localizador de MG não incorpora qualquer medida de variabilidade. Neste artigo, tal limitação é contornada por meio da utilização de uma estatística de ponderação – Máximo Global Ponderado (MGP) – semelhante ao coeficiente de variação. Esse indicador busca não penalizar de forma desproporcional situações nas quais os desvios médios, apesar de diferentes de zero, são muito pequenos. Apresentam-se evidências de que o localizador MGP reduz a distância do modelo identificado à real estrutura latente dos dados em análise, quando comparados ao modelo identificado pelo localizador não ponderado, MG. PMID:23293402

  15. Laryngeal complications by orotracheal intubation: Literature review.

    PubMed

    Mota, Luiz Alberto Alves; de Cavalho, Glauber Barbosa; Brito, Valeska Almeida

    2012-04-01

    Introdução: As lesões causadas pela intubação orotraqueal são comuns no nosso meio e amplamente relatadas pela literatura. Geralmente são causadas por acidentes na colocação do tubo ou consequência de sua permanência nas vias aéreas do paciente. Há diversos tipos de lesões laríngeas, causadas por múltiplos mecanismos.Objetivo: Verificar, na literatura, as principais causas de complicações laríngeas pós-intubação orotraqueal e seus mecanismos de lesão.Revisão de Literatura: As bases de dados pesquisadas foram LILACS, BIREME e SCIELO. Foram utilizados artigos, livros e teses, delimitando-se o período entre 1953 a 2009. As palavras-chaves utilizadas para a busca dos artigos foram: complicações, lesões, laringe, intubação, entubação, endotraqueal, orotraqueal, granulomas, estenose. Foram selecionadas 59 referências. Os critérios de inclusão utilizados para a escolha dos artigos foram os que mostraram os diversos tipos de lesões ocasionadas pela intubação orotraqueal e suas fisiopatologias.Considerações Finais: Esta revisão de literatura foi motivada pela observação na prática clínica de um grande número de sequelas laríngeas em pacientes submetidos à intubação orotraqueal. Diante disto é importante o conhecimento, pelos profissionais da área de saúde, dos tipos de complicações e de suas causas, com o intuito de evitá-las, adotando medidas de prevenção dessas lesões.

  16. Perfis de temperatura eletrônica em regiões HII

    NASA Astrophysics Data System (ADS)

    Copetti, M. V. F.

    2003-08-01

    As flutuações de temperatura eletrônica em regiões HII, inicialmente propostas para explicar as discrepâncias entre os valores de temperatura obtidos por diferentes métodos, têm sido apontadas como a causa mais provável das enormes diferenças encontradas entre as abundâncias químicas medidas através de linhas excitadas colisionalmente e de linhas de recombinação. Recentemente têm sido reportadas tentativas de detecção e quantificação diretas das flutuações de temperatura eletrônica através de medidas ponto a ponto, obtidas por meio de espectroscopia de fenda longa, das razões de linhas [OIII]l4263/l5007 e [NII]l5755/l6584, principais sensores de temperatura. Neste trabalho, utilizamos o código numérico de fotoionização Cloudy para avaliar a confiabilidade desse procedimento. Concluímos que, para valores de densidade eletrônica e de temperatura efetiva da estrela ionizante típicos das regiões HII, os perfis superficiais de temperatura obtidos via medidas do sensor [OIII]l4263/l5007 são bons traçadores dos gradientes internos de temperatura eletrônica. Já os perfis de temperatura eletrônica medidos por meio da razão [NII]l5755/l6584 não reproduzem os gradientes verdadeiros de temperatura.

  17. On sopro do magnetar

    NASA Astrophysics Data System (ADS)

    Allen, M. P.; Horvath, J. E.

    2003-08-01

    Magnetares sao estrelas de nêutrons com campos magnéticos acima do limiar quântico de 4,4´1013 G. Por causa desse intenso campo magnético, que exige período de rotação inicial da ordem de 1 ms, o torque eletromagnético é capaz de injetar 2´1052 erg, em menos de um dia, no Remanescente de Supernova (RSN) formado por ocasião da formação do magnetar. A energia injetada acelera a expansão do RSN, de modo que estimativas de idade do RSN feitas sem considerar a injeção de energia superestimarão a idade verdadeira. Além do cenário usual de formação de magnetares em colapsos gravitacionais de estrelas massivas, estudamos a possibilidade de formação dos mesmos através do Colapso Induzido por Acresção em anãs brancas. Estudamos, através de simulação numérica unidimensional, com diversas massas ejetadas e diversas densidades de meio interestelar local, as associações propostas entre candidatos a magnetar e RSNs, incluindo a injeção de energia. Concluímos que aproximadamente metade delas podem ser verdadeiras, e determinamos a faixa de velocidades e idades possíveis de cada associação. As incertezas observacionais a respeito do tamanho e densidade do meio interestelar local limitam a acurácia da análise.

  18. [Problems identified in the package leaflets of the Portuguese non-generic medicines].

    PubMed

    Pires, Carla; Cavaco, Afonso; Vigário, Marina

    2015-01-01

    Introdução: Todos os medicamentos de uso humano são comercializados com um folheto informativo. Estes documentos devem ter uma lista inicial com a identificação de todas as secções, de acordo com o modelo europeu Quality Review of Documents e não serem muito extensos, i.e. com cerca de 1500 palavras. Apenas excepcionalmente são autorizados folhetos relativos a mais de uma dose e/ ou forma farmacêutica (folhetos mistos). Neste contexto, os objectivos incluem a identificação de problemas nos folhetos informativos de todos os medicamentos não genéricos portugueses quanto à presença da lista inicial, à frequência de folhetos mistos e ao número de páginas. Material e Métodos: Consulta dos folhetos na base pública Infomed de acordo com a classificação do Prontuário Terapêutico – 10 (1º trimestre 2012). Os dados recolhidos foram sujeitos a controlo de qualidade e tratamento estatístico. Resultados: Identificação de 2729 folhetos em 3080 especialidades farmacêuticas. Foram avaliados 2042 folhetos (687 não estavam disponíveis), em que 181 (8,9%) não apresentaram lista inicial e 351 (17,2%) eram mistos. O número médio de páginas foi 6,9 (DP = 2,6), o mínimo = 2 e o máximo = 26. Discussão: A leitura e compreensão adequadas dos folhetos portugueses em alguns casos podem estar comprometidas, dado que 1) alguns dos folhetos analisados não continham a lista inicial necessária à adequada localização das informações, 2) foram detetados folhetos mistos e/ou 3) foram encontrados folhetos com uma extensão acima do desejável. Conclusão: Os resultados deste estudo devem informar o processo de desenvolvimento e aprovação dos folhetos pelos titulares da autorização da introdução no mercado e pelas autoridades reguladoras.

  19. [Weight control attempts among Portuguese adults: prevalence, motives and behavioral strategies].

    PubMed

    Santos, Inês; Andrade, Ana M; Teixeira, Pedro J

    2015-01-01

    Introdução: Em Portugal não existem dados atuais sobre tentativas de controlo do peso nem sobre estratégias e motivos na base dessas tentativas na população. Este estudo teve como objectivos determinar a prevalência das tentativas de perda/manutenção do peso e identificar as estratégias comportamentais e os motivos associados, numa amostra representativa da população adulta portuguesa. Material e Métodos: Estudo transversal constituído por 1098 indivíduos adultos. A informação sociodemográfica, os dados antropométricos e as estratégias e motivos associados à perda/manutenção do peso foram recolhidos por entrevista telefónica. Resultados: Cerca de 44% dos adultos portugueses (53% de mulheres e 35% dos homens) estão ativamente a tentar controlar o peso. Salienta-se que 22% das mulheres com peso normal tentam perder peso e que 53% dos homens e 34% das mulheres com peso excessivo não o fazem. Entre os homens, 49% com nível educacional superior estão a tentar controlar o peso versus 32% com nível educacional básico. A estratégia mais frequentemente adoptada para gerir o peso é o consumo regular de hortícolas e os motivos mais referenciados são melhorar a saúde/prevenir doenças e melhorar o bem-estar. Discussão e Conclusão: Mais de metade das mulheres e cerca de um terço dos homens em Portugal estão ativamente a tentar gerir o seu peso, utilizando estratégias comportamentais consistentes com as recomendações de saúde pública. Os motivos de saúde e bem-estar predominam sobre os restantes. Este estudo contribui para o conhecimento da gestão do peso em Portugal, alertando para o desenvolvimento de estratégias de prevenção da obesidade adequadas ao perfil da população.

  20. Determinação da massa de júpiter a partir das órbitas de seus satélites: um experimento didático

    NASA Astrophysics Data System (ADS)

    Schlickmann, M. S.; Saito, R. K.; Becker, D. A.; Rezende, M. F., Jr.; Cid Fernandes, R.

    2003-08-01

    Este trabalho apresenta o roteiro piloto de uma prática observacional em astronomia, junto com os primeiros resultados obtidos nesta fase de implementacão. O projeto, que será executado em duas etapas, visa introduzir noções de Astronomia a alunos do Ensino Médio e iniciantes nos cursos de Física. O experimento consiste em medir as órbitas dos satélites Galileanos e, a partir da análise dos dados coletados, verificar a validade da Lei das órbitas de Kepler, determinando a massa do planeta Júpiter. Em uma primeira etapa, as observações serão feitas utilizando um telescópio Meade LX200 10" e câmera CCD para obter uma seqüência de imagens do planeta, que possibilitará medir o movimento de seus satélites. A segunda etapa terá início a partir do funcionamento do telescópio em modo robótico, com a possibilidade de observações via internet por instituições de ensino. Para o desenvolvimento deste experimento foram inicialmente coletadas várias imagens de Júpiter obtidas com os instrumentos citados acima. Estas imagens serviram como base para confecção dos roteiros para a experiência no nível médio e superior. Os roteiros serão inicialmente apresentados em uma home-page. Nela também se buscará uma contextualização histórica da experiência bem como o estabelecimento de relações com professores e alunos, propostas metodológicas e a disponibilização dos programas computacionais necessários para a utilização "on-line" pelos usuários. O projeto conta com apoio da Fundação VITAE.

  1. Usina de ciências: um espaço pedagógico para aprendizagens múltiplas

    NASA Astrophysics Data System (ADS)

    Martin, V. A. F.; Poppe, P. C. R.; Orrico, A. C. P.; Pereira, M. G.

    2003-08-01

    Entendemos que o Ensino de Astronomia é especialmente apropriado para motivar os alunos e aprofundar conteúdos em diversas áreas do conhecimento, pois envolve temas ligados à Física, Matemática, Química, Computação, Tratamento de Imagens e Instrumentação de Alta Precisão, além daqueles pertinentes as áreas de Geografia, História e Antropologia. Contudo, apesar do caráter interdisciplinar que esta ciência possui, a realidade atual é que a maioria dos professores em sala de aula não foram devidamente capacitados, durante o período de formação acadêmica, para ministrar conteúdos de Astronomia nos atuais Ensinos Fundamental e Médio. Neste trabalho, discutiremos de maneira ampla, num primeiro momento, a realidade do atual ensino de ciências praticado no Estado da Bahia, apontando por dependência administrativa, o crescimento e a redução do número de escolas, da taxa de analfabetismo por faixa etária, da escolarização, do atendimento, da aprovação, reprovação e abandono, de equipamentos e laboratórios e o grau de formação dos nossos atuais professores em pleno exercício de atividade docente. Num segundo momento, discutiremos o papel do Observatório Astronômico Antares/UEFS dentro desse contexto, ou seja, suas ações implementadas ao longo dos últimos anos e em particular, o recente projeto de extensão Ensino e Difusão de Astronomia, financiado pela Fundação Vitae, que procura traduzir no lúdico, no brincar de ciências, um espaço pedagógico para aprendizagens múltiplas. Neste, o papel do professor multiplicador associado ao laboratório de kits didáticos, de fácil construção e manipulação (alguns dos quais serão mostrados), perfazem os principais veículos para o desenvolvimento de conhecimentos, atitudes, habilidades e valores que preparam os nossos alunos para a carreira técnico-científica e para sua participação crítica e criativa na Sociedade.

  2. [HIV infection and non-AIDS-defining malignancies: an outpatient clinic experience].

    PubMed

    Fevereiro, Maria do Carmo

    2014-01-01

    Introdução: Os doentes infectados pelo Vírus da Imunodeficiência Humana têm um risco elevado de desenvolver diferentes tipos de Neoplasias. Com a introdução da terapêutica anti-retroviral de alta potência, e consequente aumento da sobrevida, assistimos a uma mudança do espectro das patologias relacionadas com a infecção, nomeadamente das doenças Oncológicas, com aumento das Neoplasias Não Definidoras em deterimento das Definidoras de SIDA.Material e Métodos: Caracterização dos doentes com infecção Vírus da Imunodeficiência Humana e diagnóstico de Neoplasias Não Definidoras acompanhados ao longo de 16 anos na Consulta de Medicina/Imunodeficiência do Hospital de São José, através da consulta dos processos clínicos e avaliação retrospectiva dos aspectos demográficos, epidemiológicos, clínico-laboratoriais, tratamento e sobrevida.Resultados: Nos 1 042 doentes avaliados, foram identificados 34 casos de Neoplasias Não Definidoras, principalmente em homens (78%) e com idade mediana de 55 anos. As neoplasias mais frequentes foram: pulmão (20,6%), bexiga (17,6%), próstata (8,8%) e canal anal (5,9%), sendo o tempo médio entre o diagnóstico da infecção pelo Vírus da Imunodeficiência Humana e da Neoplasias Não Definidoras de 6,8 ± 4 anos. Na altura do diagnóstico da Neoplasias Não Definidoras a maioria dos doentes (78,8%) estava sob terapêutica anti-retroviral de alta potência, em média desde há 5,7 ± 3 anos, encontrando-se imunovirologicamente controlada. No total verificaram-se 45,5% óbitos, sobretudo em doentes com Neoplasia do pulmão (20%).Conclusão: Perante o risco de desenvolvimento de Neoplasias Não Definidoras nos doentes infectados pelo Vírus da Imunodeficiência Humana, torna-se fundamental o investimento em estratégias de prevenção, promoção de cessação tabágica e vacinação, bem como aplicação de protocolos de rastreio ajustados a esta população.

  3. Attachment Strategies and Neuroendocrine Biomarkers in Obese Children.

    PubMed

    Pinto, Inês; Wilkinson, Simon; Virella, Daniel; Alves, Marta; Calhau, Conceição; Coelho, Rui

    2016-05-01

    Introdução: A qualidade da relação pais-filho influencia o desenvolvimento do sistema fisiológico de regulação do stress da criança. Exploraram-se eventuais associações entre estratégias de vinculação e o cortisol e a hormona estimulante da tiróide, respectivamente como possíveis mediador e variável interveniente na relação mãe-filho, na criança obesa. Material e Métodos: Foi recrutada na Consulta de Obesidade uma amostra de conveniência de 83 crianças obesas com 10,9 (1,8) anos de idade (46 rapazes). A obesidade foi definida pelo percentil do índice de massa corporal para idade e género e os biomarcadores neuroendócrinos foram medidos pelos métodos de rotina. As estratégias de vinculação foram avaliadas através dos questionários (IACA) para pais e crianças. O funcionamento familiar foi classificado através do preenchimento pelos pais do FACES-III. Foram analisados modelos multivariáveis de regressão linear. Resultados: As estratégias de vinculação insegura do tipo evitante (tipo A) apresentaram uma associação significativa positiva com os níveis de hormona estimulante da tiróide e negativa com os níveis de cortisol (R2 = 0,352). As estratégias de vinculação segura (tipo B) associaram-se positivamente ao hipotiroidismo e ao percentil de índice de massa corporal, ambas com significado estatístico (R2 = 0,541). As estratégias de vinculação insegura apresentaram alguma evidência de associação positiva com a hormona estimulante da tiróide (R2 = 0,250). Discussão: Estes achados sugerem a existência de factores comuns na regulação dos eixos hipotálamo-hipófise-adrenal e hipotálamo-hipófise-tiróide. Os processos envolvidos no desenvolvimento das estratégias de vinculação do tipo A parecem associar-se aos mecanismos regulatórios do eixo HPA. Conclusão: Diferentes estratégias de vinculação estão associadas a diferentes padrões metabólicos em crianças obesas. Desconhece-se qual a sua contribui

  4. Validation of the Comply with Post-Exposure Management Among Health Care Workers Instrument for Brazil.

    PubMed

    Jansen, Adriane Corrêa; Marziale, Maria Helena Palucci; Santos, Cláudia Benedita Dos; Dantas, Rosana Aparecida Spadotti; Santos, Danielle Maria de Souza Serio Dos

    2016-01-01

    To validate the Comply with post-exposure management among healthcare workersinstrument for Nursing in Brazil. A methodological study carried out with 137 nursing professionals exposed to biological material. The existence of floor and ceiling effects was analyzed, evaluating reliability by the internal consistency of the items and test-retest reproducibility. The construct validity was analyzed by the multitrait-multi method analysis. Ceiling effects were found in two subscales. The result of the internal consistency of four subscales varied between 0.81 and 0.91. The results were considered satisfactory, while two subscales presented an unsatisfactory result (0.50 and 0.37). An evaluation of the measurement stability obtained positive results in relation to the statistical significance, with Intraclass Correlation Coefficient values between the two measurements ranging from 0.301 to 0.727; the validity of a convergent and divergent construct was confirmed by multitrait-multi method analysis, except for the Attitude subscale, which presented unsatisfactory values. The instrument presents satisfactory results for validity and reliability, except for the Attitude dimension. Validar para o Brasil o instrumento Comply with post-exposure management among health care workers para a enfermagem. Estudo metodológico realizado com 137 profissionais de enfermagem expostos a material biológico. Analisou-se a existência dos efeitos floor e ceiling e avaliou-se a fidedignidade pela consistência interna dos itens e estabilidade da medida (teste-reteste). Analisou-se a validade de construto por meio da análise multitraço-multimétodo. Verificaram-se efeitos ceiling em duas subescalas. O resultado da consistência interna, de quatro subescalas, variou entre 0,81 e 0,91, resultados considerados satisfatórios, e duas subescalas apresentaram resultado insatisfatório (0,50 e 0,37). A avaliação da estabilidade da medida obteve resultados positivos em relação à signific

  5. Developing and Testing of a Software Prototype to Support Diagnostic Reasoning of Nursing Students.

    PubMed

    de Sousa, Vanessa Emille Carvalho; de Oliveira Lopes, Marcos Venícios; Keenan, Gail M; Lopez, Karen Dunn

    2016-06-20

    To design and test educational software to improve nursing students' diagnostic reasoning through NANDA-I-based clinical scenarios. A mixed method approach was used and included content validation by a panel of 13 experts and prototype testing by a sample of 56 students. Experts' suggestions included writing adjustments, new response options, and replacement of clinical information on the scenarios. Percentages of students' correct answers were 65.7%, 62.2%, and 60.5% for related factors, defining characteristics, and nursing diagnoses, respectively. Full development of this software shows strong potential for enhancing students' diagnostic reasoning. New graduates may be able to apply diagnostic reasoning more rapidly by exercising their diagnostic skills within this software. Desenvolver e testar um protótipo de software educativo para melhorar o raciocínio diagnóstico de estudantes de enfermagem. MÉTODOS: Uma abordagem mista foi utilizada e incluiu validação de conteúdo por 13 experts e testagem do protótipo por 56 estudantes. Sugestões dos experts incluíram ajustes na escrita, inclusão de novas opções de resposta e substituição de dados clínicos nos cenários. Os percentuais de respostas corretas dos estudantes foram 65,7%, 62,2% e 60,5% para fatores relacionados, características definidoras e diagnósticos de enfermagem respectivamente. CONCLUSÃO: O desenvolvimento deste software tem um forte potencial para melhorar o raciocínio diagnóstico de estudantes. IMPLICAÇÕES PARA A PRÁTICA EM ENFERMAGEM: Através deste software, enfermeiros poderão ser capazes de exercitar o raciocínio diagnóstico e aplicá-lo mais rapidamente. © 2016 NANDA International, Inc.

  6. Discriminação de núcleos primários no Observatório Auger

    NASA Astrophysics Data System (ADS)

    Tiba, A. K. O.; Medina Tanco, G. A.; Sciutto, S. J.

    2003-08-01

    A identidade das partículas, com energias E > 10EeV, que geram chuveiros atmosféricos extensivos (CAE) na atmosfera terrestre é um incógnita. Existem diferenças sutis, mas apreciáveis entre chuveiros gerados por fótons e por núcleos, como temos demonstrado em trabalho recente. Porém entre os núcleos, as diferenças são tão sutis, que a baixa estatística e incertezas experimentais têm limitado fortemente sua diferenciação até o presente. Tal discriminação precede qualquer aplicação astrofísica mas sofisticada de raios cósmicos de ultra-alta energia. Apresentamos aqui os resultados do desenvolvimento de novos métodos de diagnóstico para a análise de CAEs com aplicação específica ao Experimento Pierre Auger. Redes neurais, combinadas com simulações numéricas detalhadas de CAEs e dos dois tipos diferentes de detectores (Cherenkov em água e de fluorescência atmosférica) presentes no experimento são empregados na análise. Mostraremos a capacidade dos métodos de diagnóstico desenvolvidos, para a discriminação de diversas distribuições hipotéticas de massa-anergia.

  7. Building inclusive health innovation systems: lessons from India.

    PubMed

    Abrol, Dinesh; Sundararaman, T; Madhavan, Harilal; Joseph, K J

    2016-11-03

    This article presents an overview of the changes that are taking place within the public and private health innovation systems in India including delivery of medical care, pharmaceutical products, medical devices, and Indian traditional medicine. The nature of the flaws that exist in the health innovation system is pinpointed. The response by the government, the health, technology and medical institutions, and the evolving industry is addressed on a national level. The article also discusses how the alignment of policies and institutions was developed within the scope of national health innovation systems, and how the government and the industry are dealing with the challenges to integrate health system, industry, and social policy development processes. Resumo: O artigo apresenta um panorama das mudanças atualmente em curso dentro dos sistemas público e privado de inovação em saúde na Índia, incluindo a prestação de serviços médicos, produtos farmacêuticos, dispositivos médicos e medicina tradicional indiana. É destacada a natureza das falhas que existem nos sistemas de inovação em saúde. As respostas do governo, das instituições médicas, de saúde e tecnologia e indústrias envolvidas, são abordadas em nível nacional. O artigo também discute como foi desenvolvido o alinhamento de políticas e instituições no escopo dos sistemas nacionais de inovação em saúde, e como governo e indústria estão lidando com os desafios para integrar o sistema de saúde, a indústria e o desenvolvimento de políticas sociais.

  8. Robotic-assisted modified retroauricular cervical approach: initial experience in Latin America.

    PubMed

    Chulam, Thiago Celestino; Lira, Renan Bezerra; Kowalski, Luiz Paulo

    2016-01-01

    to evaluate the thickness of the gastric wall at the time of intra gastric balloon (IGB) placement, at the time of its withdrawal and one month after withdrawal. fifteen morbidly obese patients underwent the introduction of IGB under general anesthesia. In all patients, there was infusion of 500ml of distilled water in the balloon for the test. Measurements of the thickness of the gastric wall were made in the antrum, body and proximal body, using a radial echoendoscope with a frequency of 12MHz and maximum zoom, and its own balloon inflated with 5ml of distilled water. the presence of IGB led to increased wall thickness of the gastric body by expanding the muscle layer. These changes were apparently transient, since 30 days after the balloon withdrawal there was a tendency to return of the wall thickness values ​​observed before the balloon insertion. the use of intragastric balloon for the treatment of obesity determines transient increase in the wall thickness of the gastric body caused by expanded muscle layer. A preocupação com a melhoria dos resultados estéticos e funcionais sem comprometimento dos resultados oncológicos na cirurgia de cabeça e pescoço tem aumentado significativamente. Os procedimentos minimamente invasivos e principalmente aqueles que utilizam a tecnologia robótica permitiram o desenvolvimento de novas abordagens, incluindo o acesso retroauricular, que agora é usado rotineiramente, especialmente na Coréia do Sul. A presente nota irá ilustrar a técnica e a experiência inicial na América Latina, demonstrando que esta abordagem é viável, segura e eficaz oncologicamente, podendo ser utilizada em casos selecionados com um benefício estético evidente.

  9. Evaluation of the Psychometric Properties of NOC Outcomes "Anxiety Level" and "Anxiety Self-Control" in a Portuguese Outpatient Sample.

    PubMed

    Sampaio, Francisco Miguel Correia; Araújo, Odete Sofia Silva Lomba; Sequeira, Carlos Alberto da Cruz; Lluch Canut, María Teresa; Martins, Teresa

    2017-01-25

    To adopt the language and to evaluate the psychometric properties of "Anxiety level" and "Anxiety self-control" NOC outcomes in Portuguese adult patients. Methodological design. The final European Portuguese version of the NOC outcome "Anxiety level," composed by 16 indicators, proved excellent internal consistency. Exploratory factor analysis (EFA) was forced to three factors. The NOC outcome "Anxiety self-control," composed of nine indicators, demonstrated a questionable internal consistency. EFA was forced to two factors. European Portuguese versions of the studied NOC outcomes proved to be tools with acceptable psychometric properties for evaluating anxiety in Portuguese patients. This study contributed to the development of NOC language and to the enrichment of nursing's body of knowledge. Adaptar a linguagem e avaliar as propriedades psicométricas dos resultados NOC "Nível de ansiedade" e "Autocontrolo da ansiedade" em utentes portugueses adultos. MÉTODOS: Estudo metodológico. A versão portuguesa do resultado NOC "Nível de ansiedade", composta por 16 indicadores, apresentou uma excelente consistência interna. A análise fatorial exploratória (AFE) foi forçada a três dimensões. O resultado NOC "Autocontrolo da ansiedade", composto por nove indicadores, apresentou uma consistência interna questionável. A AFE foi forçada a duas dimensões. CONCLUSÕES: As versões portuguesas dos resultados NOC estudados são instrumentos com propriedades psicométricas aceitáveis para avaliar a ansiedade em utentes portugueses. IMPLICAÇÕES PARA A PRÁTICA DE ENFERMAGEM: Este estudo contribuiu para o desenvolvimento da linguagem NOC e para enriquecer o corpo de conhecimento de Enfermagem. © 2017 NANDA International, Inc.

  10. Patient safety and nursing: interface with stress and Burnout Syndrome.

    PubMed

    Rodrigues, Cláudia Cristiane Filgueira Martins; Santos, Viviane Euzébia Pereira; Sousa, Paulo

    2017-01-01

    To analyze studies on stress, Burnout Syndrome, and patient safety in the scope of nursing care in the hospital environment. This was an integrative literature review. Data collection was performed in February 2016 in the following databases: Medical Literature Analysis and Retrieval System Online - PubMed/MEDLINE, Latin American and Caribbean Literature in Health Sciences - LILACS. Ten scientific productions were selected, which listed that factors contributing to stress and Burnout Syndrome of nursing professionals are the work environment as a source of stress, and excessive workload as a source of failures. The analysis found that the stress and Burnout Syndrome experienced by these professionals lead to greater vulnerability and development of unsafe care, and factors such as lack of organizational support can contribute to prevent these failures. Analisar estudos que versam sobre o estresse e Síndrome de Burnout, bem como a segurança do paciente no âmbito da assistência de enfermagem no ambiente hospitalar. Tratou-se de uma revisão integrativa de literatura. O levantamento dos dados foi efetuado nas bases de dados Medical Literature Analysis and Retrieval System Online - PubMed / MEDLINE, Literatura Latino-Americana e do Caribe em Ciências da Saúde -LILACS em fevereiro de 2016. Foram selecionadas10 produções científicas que apontaram que os fatores que contribuem para o estresse e a Síndrome de Burnout dos profissionais de enfermagem são o ambiente de trabalho como fonte de estresse e a carga de trabalho excessiva como geradora de falhas. A análise apontou que o estresse e a Síndrome de Burnout vivenciada por esses profissionais acarretam maior vulnerabilidade ao desenvolvimento de uma assistência insegura e que fatores como a falta de apoio organizacional podem contribuir para dirimir essas falhas.

  11. Percepção Astronômica de Alunos do Ensino Médio da Rede Estadual de São Paulo

    NASA Astrophysics Data System (ADS)

    de Oliveira, E. F.; Voelzke, M. R.; Amaral, L. H.

    2005-08-01

    Embora a astronomia seja uma das ciências mais antigas da humanidade e muitos dos conceitos astronômicos serem populares, principalmente nesta época de alta globalização do conhecimento por intermédio de eficientes meios de comunicação e de obtenção da informação, notadamente através da internet, observa-se que uma parcela significativa dos estudantes encontra-se à margem dessas informações. O presente trabalho visa analisar o nível de conhecimento básico dos alunos de Ensino Médio da rede estadual da cidade de Suzano quanto aos fenômenos astronômicos que os rodeiam, tais como a sucessão dos dias e das estações do ano, além de questioná-los sobre fatos genéricos tais como: quais são os astros que se encontram mais próximos do planeta Terra, o que vem a ser o Sol, o Big Bang, um ano-luz, uma estrela cadente, a estrela de Bélem e o que ocasionou a extinção dos dinossauros. Para tanto foi elaborado um formulário constando de questões de múltipla escolha, o qual foi aplicado no primeiro colegial noturno da Escola Estadual Batista Renzi. Num espaço amostral de 34 alunos constatou-se que apenas 29,4% compreendiam a sucessão dos dias da semana, que apenas 20,6% explicaram corretamente as estações do ano, que apenas 20,6% tinham idéia de quais são os objetos celestes mais próximos da Terra, em contraposição 67,6% sabiam classificar corretamente o Sol como estrela, 55,9% relacionavam o Big Bang à origem do universo, apenas 20,6% identificavam um ano-luz como unidade de distância, 32,4% reconheciam uma estrela cadente como meteoro, 41,2% consideravam a estrela de Belém como um cometa e 50,0% explicaram corretamente a extinção dos dinossauros. A presente análise será expandida para as demais classes de primeiro colegial, não somente do período noturno, mas também do diurno da Escola Estadual Batista Renzi, bem como o formulário será devidamente ampliado. Já nesta primeira fase nota-se claramente o pequeno discernimento

  12. Measuring the quality of life in hypertension according to Item Response Theory.

    PubMed

    Borges, José Wicto Pereira; Moreira, Thereza Maria Magalhães; Schmitt, Jeovani; Andrade, Dalton Francisco de; Barbetta, Pedro Alberto; Souza, Ana Célia Caetano de; Lima, Daniele Braz da Silva; Carvalho, Irialda Saboia

    2017-05-04

    To analyze the Miniquestionário de Qualidade de Vida em Hipertensão Arterial (MINICHAL - Mini-questionnaire of Quality of Life in Hypertension) using the Item Response Theory. This is an analytical study conducted with 712 persons with hypertension treated in thirteen primary health care units of Fortaleza, State of Ceará, Brazil, in 2015. The steps of the analysis by the Item Response Theory were: evaluation of dimensionality, estimation of parameters of items, and construction of scale. The study of dimensionality was carried out on the polychoric correlation matrix and confirmatory factor analysis. To estimate the item parameters, we used the Gradual Response Model of Samejima. The analyses were conducted using the free software R with the aid of psych and mirt. The analysis has allowed the visualization of item parameters and their individual contributions in the measurement of the latent trait, generating more information and allowing the construction of a scale with an interpretative model that demonstrates the evolution of the worsening of the quality of life in five levels. Regarding the item parameters, the items related to the somatic state have had a good performance, as they have presented better power to discriminate individuals with worse quality of life. The items related to mental state have been those which contributed with less psychometric data in the MINICHAL. We conclude that the instrument is suitable for the identification of the worsening of the quality of life in hypertension. The analysis of the MINICHAL using the Item Response Theory has allowed us to identify new sides of this instrument that have not yet been addressed in previous studies. Analisar o Miniquestionário de Qualidade de Vida em Hipertensão Arterial (MINICHAL) por meio da Teoria da Resposta ao Item. Estudo analítico realizado com 712 pessoas com hipertensão arterial atendidas em 13 unidades de atenção primária em saúde de Fortaleza, CE, em 2015. As etapas da an

  13. [Diabetes mellitus and its influence on the success of endodontic treatment: a retrospective clinical study].

    PubMed

    Ferreira, Manuel Marques; Carrilho, Eunice; Carrilho, Francisco

    2014-01-01

    apical nos doentes diabéticos. Em relação à avaliação do sucesso dos tratamentos endodônticos analisados verificou-se que a percentagem de sucesso nos doentes diabéticos é mais baixa, embora não seja estatisticamente significativa. Por este motivo e dadas as limitações deste estudo, não se pode afirmar que doentes com diabetes mellitus têm maior predisposição para o desenvolvimento de lesõesperiradiculares ou que o sucesso dos tratamentos endodônticos nestes doentes esteja comprometido. É importante, no entanto, que sejam desenvolvidos mais estudos de forma a caracterizar as alterações pulpares e periradiculares e a avaliar a prevalência da periodontiteapical e sua progressão em doentes com diabetes mellitus.

  14. Tool and ideological knowledge in Street Outreach Office working process.

    PubMed

    Kami, Maria Terumi Maruyama; Larocca, Liliana Muller; Chaves, Maria Marta Nolasco; Piosiadlo, Laura Christina Macedo; Albuquerque, Guilherme Souza

    2016-01-01

    To identify ideological knowledge and tool knowledgethat provide support to the Street Outreach Office working process. Qualitative and exploratory research. TwentyStreet Outreach Office professionals and six users collected the data, applying different semi-structured interview schedules for each category of participants. The resulting categories were analyzed in light of tool and ideological knowledge presented in the working process. From the participant discourses the following ideological knowledge emerged: public policies and the needs of the person ina street situation and tool knowledge, as well as devices and tools for the care of people in street situations and a weekly schedule. The focus on the working process discourse, supported by ideological knowledge, was verified. The structural dimension of the objective reality of the population in street situations was perceptible in the social determination of being situating on the street. When daily situations were revealed, the limitations to be overcome in the working process context were noticed. Identificar os saberes ideológicos e instrumentais que subsidiam o processo de trabalho do Consultório na Rua. Pesquisa qualitativa e exploratória. A coleta de dados foi realizada junto a 20 profissionais e seis usuários do Consultório na Rua de um município do sul do Brasil, por meio de entrevistas com roteiros semiestruturados distintos para cada categoria de participantes. As classes resultantes foram analisadas à luz dos saberes ideológicos e instrumentais presentes no processo de trabalho. Dos discursos dos participantes emergiram os saberes ideológicos: políticas públicas e necessidades da pessoa em situação de rua e os saberes instrumentais: dispositivos e instrumentos no cuidado à pessoa em situação de rua e agenda semanal. Constatou-se a centralidade dos discursos no processo de trabalho, sustentado pelos saberes ideológicos. A dimensão estrutural da realidade objetiva da população em

  15. Residual volume in vials of antibiotics used in pediatrics.

    PubMed

    Chaves, Caroline Magna Pessoa; Bezerra, Carolina Martins; Lima, Francisca Elisângela Teixeira; Cardoso, Maria Vera Lúcia Moreira Leitão; Fonseca, Said Gonçalves da Cruz; Silva, Viviane Martins da

    2017-06-12

    melhorias na gestão dos antibióticos na instituição em estudo, para que o volume excedente do antibiótico em frasco-ampola seja aproveitado até o tempo de estabilidade permitido, assim como é necessário que haja a adequação da forma de descarte do volume residual, que apresenta risco à saúde pública e ao meio ambiente.

  16. Guide of attributes of the nurse's political competence: a methodological study.

    PubMed

    Melo, Wesley Soares de; Oliveira, Paulo Jorge Ferreira de; Monteiro, Flávia Paula Magalhães; Santos, Francisca Carla Dos Angelos; Silva, Maria Janaína Nogueira da; Calderon, Carolina Jimenez; Fonseca, Lilian Nara Amaral da; Simão, Ana Adélia Chaves

    2017-01-01

    To build and validate a guide of attributes of the nurse's political competence. Methodological research. This study comprised the construction of the instrument through literature review; experts validation of pre-established attributes for composing the guide; and clinical validation in the nurses work environment/reality. The data collection took place in the months from August to October 2014, and the analysis was based on the content analysis of Bardin and use of Epi info 3.5. All ethical precepts have been complied with. From 29 attributes found in the literature, 25 have been validated by experts. Clinical/practical validation involved the participation of 43 nurses, who observed that the attributes are not articulated with the professional practices developed by them. The attributes of the nurse's political competence were identified with support of literature. It is concluded that the professionals still have limited and fragmented perception of political competence, expressing difficulty/limitation. Construir e validar um guia de atributos da competência política do enfermeiro. Pesquisa metodológica. O estudo compreendeu a construção do instrumento por meio de revisão da literatura; validação, por especialistas, dos atributos preestabelecidos para composição do guia; e validação clínica no ambiente/realidade de trabalho dos enfermeiros. A coleta dos dados ocorreu nos meses de agosto a outubro de 2014, e a análise baseou-se na análise de conteúdo de Bardin e utilização do Epi info 3.5. Foram respeitados todos os preceitos éticos. Dos 29 atributos encontrados na literatura, 25 foram validados pelos especialistas. A validação clínica/prática envolveu a participação de 43 enfermeiros, os quais observaram que os atributos não apresentam articulação com as práticas profissionais por eles desenvolvidas. Identificados os atributos da competência política do enfermeiro com apoio da literatura. Conclui-se que os profissionais ainda

  17. Professionals and interfamily violence against children and adolescents: in between legal and conceptual precepts.

    PubMed

    Schek, Gabriele; Silva, Mara Regina Santos da; Lacharité, Carl; Bueno, Maria Emilia Nunes

    2016-01-01

    To identify the conceptions of professionals regarding interfamily violence against children and adolescents. A qualitative study conducted with 15 professionals who had taken children and adolescents under their care as a result of interfamily violence. Data were collected between November, 2013, and March, 2015, through semi-structured interviews. Data were organized and analyzed using the Textual Discourse Analysis technique. The professional discourse highlighted that some legal aspects regarding the handling of interfamily violence against children and adolescents are neglected; an omission supported by the justification of professionals to preserve the family. We highlight the confrontation between the concept of family as a caregiver and the family that commits violence against children, in addition to the positioning of professionals, which does not include the family or the aggressor in the intervention process in facing situations of interfamily violence attended to by the services. Acting against interfamily violence requires professionals to do away with some pre-established concepts in ordee to put the actual needs of victims and families into evidence. Identificar, com base no discurso dos profissionais, suas concepções a respeito da violência intrafamiliar contra crianças e adolescentes. Estudo qualitativo, realizado com 15 profissionais, que tiveram sob seus cuidados crianças e adolescentes atendidas em decorrência da violência intrafamiliar. Os dados foram coletados entre novembro de 2013 e março de 2015, por meio de entrevistas semiestruturadas. Os dados foram organizados e analisados utilizando a técnica de Análise Textual Discursiva. O discurso dos profissionais colocou em evidência que alguns aspectos legais em relação ao manejo da violência intrafamiliar contra crianças e adolescentes são negligenciados, omissão respaldada pela justificativa dos profissionais de preservar a família. Destaca-se o confronto entre a concep

  18. [Habitat heterogeneity, richness and structure of assemblages of dung beetles (Scarabaeidae: Scarabaeinae) in areas of cerrado in the Chapada dos Parecis, Mato Grosso state, Brazil].

    PubMed

    Silva, Ricardo J da; Diniz, Soraia; Vaz-de-Mello, Fernando Z

    2010-01-01

    Ecological theory of habitat heterogeneity and limited niche-similarity assumes that more heterogeneous environments provide a greater amount and diversity of resources than simple environments, resulting in a greater diversity of species. This study aimed to evaluate the effect of the habitat heterogeneity on the richness of dung beetles and to examine the spatial patterns of assemblage structure in relation to patterns of habitat heterogeneity. Dung beetles were collected using pitfall traps without bait in 30 points distributed in an area of cerrado sensu lato, in the region of Tangará da Serra, MT, Brazil, including areas of cerrado sensu stricto, campo sujo, cerradão and gallery forest. A total of 1,291 dung beetles were collected, distributed in 16 genera and 29 species. Overall habitat heterogeneity exerted a negative effect on patterns of dung beetles richness. Higher levels of species richness were observed in areas of cerrado campo sujo, while the areas of gallery forest were the most species poor. Regarding assembly structure, it was found that the dung beetles were separated into two major groups, one formed by the presence of specialized species in forest areas and other composed of species that occurred predominantly in cerrado. In conclusion, it was found that habitat complexity influenced the distribution of dung beetles, but the level of turnover in species composition along the heterogeneity gradient was relatively weak.

  19. Efeitos dos sais na planta e tolerância das culturas à salinidade (Salinity effects on plants and tolerance of crops to salinity)

    USDA-ARS?s Scientific Manuscript database

    The major challenge for world agriculture today is to maintain food and water supplies that can meet the demands of a growing world population. The shortage of fresh water, and its use mainly for human consumption, leaves the farmers with the choice of using reclycled city water, or underground sali...

  20. El Proyecto Cunningham: Dos Idiomas; Muchos Paises, 1995-96 (The Cunningham Project: Two Languages, Many Countries, 1995-96). Research Report on Educational Grants.

    ERIC Educational Resources Information Center

    Houston Independent School District, TX. Dept. of Research and Evaluation.

    This report presents an evaluation of a two-way bilingual program in English and Spanish at the Cunningham Elementary School (Texas). The program was designed to extend and expand educational reform by shifting the instructional program at the school over the 5-year time span from a transitional bilingual program to a two-way bilingual, or dual…

  1. Neodymium, strontium and chromium isotopic studies of the LEW86010 and Angra dos Reis meteorites and the chronology of the angrite parent body

    NASA Technical Reports Server (NTRS)

    Nyquist, L. E.; Bansal, B.; Wiesmann, H.; Shih, C.-Y.

    1994-01-01

    Neodymium, stontium, and chromium isotopic studies of the LEW86010 angrite established its absolute age and the formation interval between its crystallization and condensation of Allende CAIs from the solar nebula. Pyroxene and phosphate were found to contain approximately 8% of its Sm and Nd inventory. A conventional Sm-147-Nd-143 isochron yielded an age of 4.53 +/- 0.04 Ga (2 sigma and Epsilon(sub Nd sup 143)) = 0.45 +/- 1.1. An Sm-146-Nd-142 isochron gives initial Sm-146/Sm-144 = 0.0076 +/- 0.0009 and Epsilon (sub Nd sup 142) = -2.5 +/- 0.4. The Rb-Sr analyses give initial Sr-87/Sr-86 Iota(sub Sr sup 87) = 0.698972 +/- 8 and 0.698970 +/- 18 for LEW and ADOR, respectively, relative to Sr-87/Sr-86 = 0.71025 for NBS987. The difference, Delta Iota(sub Sr Sup 87), between Iota (sub sr sup 87) for the angrites and literature values for Allende CAIs, corresponds to approximately Ma of growth in a solar nebula with a CI chondrite value of Rb-87/Sr-86 = 0.91, or approximately 5 Ma in a nebula with solar photospheric Rb-87/Sr-86 = 1.51. Excess Cr-53 from extinct Mn-53(t(sub 1/2) = 3.7 Ma)in LEW86010 corresponds to initial Mn-53/Mn-55 = 4.4 +/- 1.0 x 10(exp -5) for the inclusions as previously reported by the Paris group (Birck and Allegre, 1988). The Sm-146/Sm-144 value found for LEW86010 corresponds to solar system initial (Sm-146/Sm-144) = 0.0080 +/- 0.0009 for crystallization 8 Ma after Allende, the difference between Pb-Pb ages of angrites and Allende, or 0.0086 +/- 0.0009 for crystallation 18 Ma after Allende, using the Mn-Cr formation interval. The isotopic data are discussed in the context of a model in which an undifferentiated 'chondritic' parent body formed from the solar nebula approximately Ma after Allende CAIs and subsequently underwent differentiation accompanied by loss of volatiles. Parent bodies with Rb/Sr similar to that of CI, CM, or CO chondrites could satisfy the Cr and Sr isotopic systematics. If the angrite parent body had Rb/Sr similar to that of CV meteorites, it would have to form slightly later, approximately 2.6 Ma after the CAIs, to satisfy the Sr and CR isotopic systematics.

  2. Dos Idiomas, Un Mundo Dual Language Project Title VII Third-Year Evaluation Report, 1997-98. Publication Number 97.21.

    ERIC Educational Resources Information Center

    Liberty, Paul; Gonzalez, Rosa Maria

    An evaluation was conducted of the third year of a 5-year comprehensive bilingual education grant funded by Title VII of the Improving America's Schools Act of 1994. The grant funds a program of developmental bilingual education at two elementary schools in the Austin Independent School District (Texas). More than 25% of the students at each…

  3. Sanchez and Metz Elementary Schools: Dos Idiomas, Un Mundo. Dual Language Project. Title VII First-Year Evaluation Report, 1995-96.

    ERIC Educational Resources Information Center

    Ernest, Harishini M.; Gonzalez, Rosa Maria

    The first-year evaluation of a two-way Spanish/English bilingual education program at two Austin (Texas) elementary schools is presented. The developmental program has as its objectives the development of students' oral proficiency in Spanish and English, development of grade-level appropriate literacy in both languages, increase in academic…

  4. La investigacion sobre la calidad de los programas para ninos de hasta dos anos de edad (Research on Quality in Infant-Toddler Programs). ERIC Digest.

    ERIC Educational Resources Information Center

    Honig, Alice Sterling

    Concern about the quality of infant-toddler care programs has grown recently in response to two factors. The first is the need of employed parents for such care, and the second is research emphasizing the importance of brain development in the early years. This Spanish-language Digest introduces some of the many issues related to the quality of…

  5. Claves y pautas graficas en la determinacion de edad en dos especies del genero Thryothorus (Troglodytidae) en el Pacifico de Nicaragua

    Treesearch

    Marvin Torrez; Wayne J. Arendt

    2011-01-01

    Photographic key to determine age in two Thryothorus wrens from Nicaragua's Pacific slope. – We used plumage and molt characteristics to determine age in two Neotropical species of the family Troglodytidae, Rufous-and-White Wren (Thryothorus rufalbus) and Plain Wren (T. modestus). Color density, shape, and strength of the black barring in the remiges, rectrices,...

  6. Determinación fotométrica de parámetros fundamentales de dos cúmulos abiertos del cuarto cuadrante Galáctico

    NASA Astrophysics Data System (ADS)

    Marcionni, N.; Parisi, M. C.; Clariá, J. J.; Ahumada, A. V.; Palma, T.; Piatti, A. E.

    We present preliminary results obtained from a photometric analysis in the Washington system C and T_{1} passbands of two poorly known open clusters (OCs) located in the fourth Galactic quadrant: BH 84 and BH 211. Based on the best fits of theoretical isochrones to the (T_1,C-T_1) colour- magnitude diagrams, we derive the fundamental cluster parameters. The present results are part of a major project which aims to characterize almost a hundred OCs observed and analyzed in a homogeneous way. FULL TEXT IN SPANISH

  7. How Do You Say "Twos" in Spanish, if "Two" Is "Dos"? Language as Means and Object in a Bilingual Kindergarten Classroom

    ERIC Educational Resources Information Center

    Mulvihill, Naomi

    2014-01-01

    In this essay Naomi Mulvihill uses vignettes from her bilingual kindergarten classroom to explore the dynamic processes by which young children make sense of language, focusing on instances in which she asks her students to compare texts presented in English and Spanish. Using Piaget's concept of disequilibrium as a guiding framework,…

  8. Bochum 14 y Lynga 14: dos cúmulos jóvenes proyectados en dirección al centro galáctico

    NASA Astrophysics Data System (ADS)

    Rizzo, L.; Vázquez, R. A.; Carraro, G.

    2017-10-01

    We present CCD photometry of the open clusters Bochum 14 and Lyng 14, both located no more than twenty degrees from the galactic center and on the disk. Our data reveal the presence of true open clusters with a high reddening, since we are observing the inner zone of the galaxy. They would be located in the interarm zone, between Carina-Sagittarius and Scutum-Centaurus, at a distance close to 2 Kpc. We also analyse the star field on which the clusters are projected.

  9. Neodymium, strontium and chromium isotopic studies of the LEW86010 and Angra dos Reis meteorites and the chronology of the angrite parent body

    NASA Technical Reports Server (NTRS)

    Nyquist, L. E.; Bansal, B.; Wiesmann, H.; Shih, C.-Y.

    1994-01-01

    Neodymium, stontium, and chromium isotopic studies of the LEW86010 angrite established its absolute age and the formation interval between its crystallization and condensation of Allende CAIs from the solar nebula. Pyroxene and phosphate were found to contain approximately 8% of its Sm and Nd inventory. A conventional Sm-147-Nd-143 isochron yielded an age of 4.53 +/- 0.04 Ga (2 sigma and Epsilon(sub Nd sup 143)) = 0.45 +/- 1.1. An Sm-146-Nd-142 isochron gives initial Sm-146/Sm-144 = 0.0076 +/- 0.0009 and Epsilon (sub Nd sup 142) = -2.5 +/- 0.4. The Rb-Sr analyses give initial Sr-87/Sr-86 Iota(sub Sr sup 87) = 0.698972 +/- 8 and 0.698970 +/- 18 for LEW and ADOR, respectively, relative to Sr-87/Sr-86 = 0.71025 for NBS987. The difference, Delta Iota(sub Sr Sup 87), between Iota (sub sr sup 87) for the angrites and literature values for Allende CAIs, corresponds to approximately Ma of growth in a solar nebula with a CI chondrite value of Rb-87/Sr-86 = 0.91, or approximately 5 Ma in a nebula with solar photospheric Rb-87/Sr-86 = 1.51. Excess Cr-53 from extinct Mn-53(t(sub 1/2) = 3.7 Ma)in LEW86010 corresponds to initial Mn-53/Mn-55 = 4.4 +/- 1.0 x 10(exp -5) for the inclusions as previously reported by the Paris group (Birck and Allegre, 1988). The Sm-146/Sm-144 value found for LEW86010 corresponds to solar system initial (Sm-146/Sm-144) = 0.0080 +/- 0.0009 for crystallization 8 Ma after Allende, the difference between Pb-Pb ages of angrites and Allende, or 0.0086 +/- 0.0009 for crystallation 18 Ma after Allende, using the Mn-Cr formation interval. The isotopic data are discussed in the context of a model in which an undifferentiated 'chondritic' parent body formed from the solar nebula approximately Ma after Allende CAIs and subsequently underwent differentiation accompanied by loss of volatiles. Parent bodies with Rb/Sr similar to that of CI, CM, or CO chondrites could satisfy the Cr and Sr isotopic systematics. If the angrite parent body had Rb/Sr similar to that of CV meteorites, it would have to form slightly later, approximately 2.6 Ma after the CAIs, to satisfy the Sr and CR isotopic systematics.

  10. El Proyecto Cunningham: Dos Idiomas; Muchos Paises, 1995-96 (The Cunningham Project: Two Languages, Many Countries, 1995-96). Research Report on Educational Grants.

    ERIC Educational Resources Information Center

    Houston Independent School District, TX. Dept. of Research and Evaluation.

    This report presents an evaluation of a two-way bilingual program in English and Spanish at the Cunningham Elementary School (Texas). The program was designed to extend and expand educational reform by shifting the instructional program at the school over the 5-year time span from a transitional bilingual program to a two-way bilingual, or dual…

  11. Yo Ciudadano: Un Curriculo de Experiencias para Educacion Civica. Nivel: Dos (Citizen Me: An Experiential Curriculum for Citizenship Education. Level: Two).

    ERIC Educational Resources Information Center

    Lantz, Jean

    Integrating concepts of basic citizenship education with community involvement, this experiential curriculum provides a means for developing decision making and critical thinking skills within the existing second grade social studies curriculum. The 10 lessons, translated into Spanish, cover the following concepts: friendly, unfriendly and…

  12. En Busqueda de la Escuela del Siglo XXI: Dos Experiencias de Autoaprendizaje (In Search of the 21st Century School: Two Self-Learning Experiences).

    ERIC Educational Resources Information Center

    Schiefelbein, Ernesto; And Others

    This book is a contribution to the dialogue that is maintained today around the problems of education. The book contains four parts: (1) "In Search of the 21st Century School. Can the Colombian New School (EN) Show Us the Way?"; (2) "Experimentation with Self-Learning Materials in Two Schools in Conchali (Chile)"; (3)…

  13. Heterologous production and detection of recombinant directing 2-deoxystreptamine (DOS) in the non-aminoglycoside-producing host Streptomyces venezuelae YJ003.

    PubMed

    Kurumbang, Nagendra Prasad; Oh, Tae-Jin; Liou, Kwangkyoung; Sohng, Jae Kyung

    2008-05-01

    2-Deoxystreptamine is a core aglycon that is vital to backbone formation in various aminoglycosides. This core structure can be modified to develop hybrid types of aminoglycoside antibiotics. We obtained three genes responsible for 2-deoxystreptamine production, neo7, neo6, and neo5, which encode 2-deoxy-scyllo-inosose synthase, L-glutamine: 2-deoxy-scyllo-inosose aminotransferase, and dehydrogenase, respectively, from the neomycin gene cluster. These genes were cloned into pIBR25, a Streptomyces expression vector, resulting in pNDOS. The recombinant pNDOS was transformed into a non-aminoglycoside-producing host, Streptomyces venezuelae YJ003, for heterologous expression. Based on comparisons of the retention time on LC-ESI/MS and ESIMS data with those of the 2-deoxystreptamine standard, a compound produced by S. venezuelae YJ003/pNDOS was found to be 2-deoxystreptamine.

  14. A Educacao dos Portadores de Necessidades Especiais no Brasil no Periodo de 1910 a 1949 (Education of Those with Special Needs in Brazil from 1920 to 1949).

    ERIC Educational Resources Information Center

    Marques, Carlos Alberto; Santiago, Mylene Cristina; de Moura, Simone Moreira

    2000-01-01

    Examines education given to those with special needs in Brazil from 1910-1949. Shows the dichotomy of meanings in which the education of special needs persons during that period, besides being marked by concepts related to the exclusion paradigm, already indicated signs of respect for diversity and civil rights. (BT)

  15. A Educacao dos Portadores de Necessidades Especiais no Brasil no Periodo de 1910 a 1949 (Education of Those with Special Needs in Brazil from 1920 to 1949).

    ERIC Educational Resources Information Center

    Marques, Carlos Alberto; Santiago, Mylene Cristina; de Moura, Simone Moreira

    2000-01-01

    Examines education given to those with special needs in Brazil from 1910-1949. Shows the dichotomy of meanings in which the education of special needs persons during that period, besides being marked by concepts related to the exclusion paradigm, already indicated signs of respect for diversity and civil rights. (BT)

  16. Con un pie en dos islas: cultural bridges that inform sexual and reproductive health in the Dominican Republic and New York.

    PubMed

    Breitbart, Vicki; Morales, Haydee; Brown, Jaweer; Betances, Bethania; Kahalnik, Farra

    2010-06-01

    Immigrants from the Dominican Republic have grown in number and currently make up a substantial portion of New York City's population. In order to better understand the cultural context of Dominican women's sexual and reproductive health attitudes and practices, focus groups were conducted with Dominican women living in New York City as well as with women living in the Dominican Republic. Analysis found that women in the USA had more economic independence and a greater sense of freedom in regards to sexuality than women in the Dominican Republic. However, those in New York City also hoped to maintain their cultural identity in many ways. Women associated the prevalence of gender-based violence with male unemployment and alcohol abuse. Women in both locales reported limited condom use and saw contraception as a woman's responsibility. Many barriers to using the healthcare system were identified and, in many cases, there exists a preference for herbal treatments and folk remedies. This study provided many important insights that have the potential to increase the quality of sexual and reproductive health care for Dominican women.

  17. How Do You Say "Twos" in Spanish, if "Two" Is "Dos"? Language as Means and Object in a Bilingual Kindergarten Classroom

    ERIC Educational Resources Information Center

    Mulvihill, Naomi

    2014-01-01

    In this essay Naomi Mulvihill uses vignettes from her bilingual kindergarten classroom to explore the dynamic processes by which young children make sense of language, focusing on instances in which she asks her students to compare texts presented in English and Spanish. Using Piaget's concept of disequilibrium as a guiding framework,…

  18. Análise da aplicação e dos resultados do modelo OPM3® para a área da saúde

    PubMed Central

    Augusto dos Santos, Luis; de Fátima Marin, Heimar

    2015-01-01

    Esta pesquisa procurou analisar se um modelo de questionário criado por uma comunidade internacional de gerenciamento de projetos e se é aplicavél a organizações voltadas a área de saúde. O modelo OPM3® (Organizational Project Management Maturity Model) foi criado para que organizações de qualquer área ou porte pudessem identificar a presença, ou ausência, de boas práticas de gerenciamento. O objetivo da aplicação desse modelo é avaliar sempre a organização e não o entrevistado. No presente artigo, são apresentados os resultados da aplicação desse modelo em uma organização que possuía produtos e serviços de tecnologia da informação aplicados à área de saúde. Este estudo verificou que o modelo é aplicável de forma rápida e que a organização analisada possuía um número expressivo de boas práticas. PMID:26924862

  19. International Symposium on Spacecraft Ground Control and Flight Dynamics, SCD1, Sao Jose dos Campos, Brazil, Feb. 7-11, 1994

    NASA Astrophysics Data System (ADS)

    Rozenfeld, Pawel; Kuga, Helio Koiti; Orlando, Valcir

    An international symposium on spacecraft flight dynamics and ground control systems produced 85 papers in the areas of attitude determination and control, orbit control, satellite constellation strategies, stationkeeping, spacecraft maneuvering, orbit determination, astrodynamics, ground command and control systems, and mission operations. Several papers included discussions on the application of artificial intelligence, neural networks, expert systems, and ion propulsion. For individual titles, see A95-89098 through A95-89182.

  20. Plug in to the Utah Library Network, Reach Out to the World. Utah Library Network and Internet Training Handbook [for DOS]. Information Forum Publication #7.

    ERIC Educational Resources Information Center

    Reinwand, Louis; And Others

    This manual is designed to assist public libraries in Utah in their use of the Internet. Many of the examples used were created specifically to explain the use of products that the Utah Library Network provides for public libraries in Utah. The introduction provides background history and general information about the Internet and general…

  1. Teamwork in nursing: restricted to nursing professionals or an interprofessional collaboration?

    PubMed

    Souza, Geisa Colebrusco de; Peduzzi, Marina; Silva, Jaqueline Alcântara Marcelino da; Carvalho, Brígida Gimenez

    2016-01-01

    To understand the nursing professionals' conceptions of teamwork and their elements. A qualitative study conducted in an oncological hospital using a semi-structured interview with 21 nursing professionals. Two conceptions emerged from the accounts: teamwork restricted to nursing professionals and teamwork with interprofessional collaboration with particular importance for interactive dimensions: communication, trust and professional bonds, mutual respect and recognition of the other's work, collaboration, and conflict, with this last subcategory considered as an obstacle to teamwork. Nursing conceives teamwork as an interprofessional practice, which is a result of the quality of interaction among professionals from different areas and involves the recognition and handling of conflicts. Compreender as concepções dos profissionais de enfermagem sobre trabalho em equipe e seus elementos constituintes. Pesquisa qualitativa, realizada em hospital oncológico, por meio de entrevista semiestruturada com 21 profissionais de enfermagem. Duas concepções emergiram dos relatos, trabalho em equipe circunscrito à enfermagem e trabalho em equipe com colaboração interprofissional, com destaque para dimensão interativa: comunicação, confiança e vínculo, respeito mútuo e reconhecimento do trabalho do outro, colaboração e conflito. Esta última subcategoria foi apontada como obstáculo para o trabalho em equipe. A enfermagem concebe majoritariamente o trabalho em equipe como ação interprofissional, e isto decorre da qualidade da interação entre os profissionais das diferentes áreas e o reconhecimento e manejo de conflitos.

  2. Judicial demand of medications through the Federal Justice of the State of Paraná.

    PubMed

    Nisihara, Renato Mitsunori; Possebom, Ana Carolina; Borges, Luiza de Martino Cruvinel; Shwetz, Ana Claudia Athanasio; Bettes, Fernanda Francis Benevides

    2017-01-01

    To describe the profile of lawsuits related to drug requests filled at the Federal Justice of the State of Paraná. A cross-sectional study, and the data were obtained through consulting the lawsuits at the online system of the Federal Justice of Paraná. Out of 347 lawsuits included in the study, 55% of plaintiffs were women, with a median age of 56 years. Oncology was the field with more requests (23.6%), and the highest mean costs. A wide variety of diseases and broad variety of requested drugs were found in the lawsuits. Approximately two-thirds of them were requested by the brand name, and the most often requested drugs were palivizumab and tiotropium bromide. Only 14.5% of the requested medicines were registered in the National Medication Register. The Public Defender's Office filled actions in 89.6% of cases and all lawsuits had an interim relief. The mean time for approval was 35 days and 70% of requests were granted. Oncology was the field with the highest demand for medicines at the Federal Justice of Paraná in 2014. A great variety of medications was requested. The Public Defender´s Office represented most lawsuits. All demands had an interim relief, and the majority of requests were granted, within an average of 35 days. Descrever o perfil das ações que solicitam medicamentos ajuizadas na Justiça Federal do Paraná. Estudo transversal descritivo, cujos dados foram obtidos por meio de consulta aos processos no sistema on-line da Justiça Federal do Paraná. Dentre os 347 processos incluídos no estudo, 55% dos autores eram mulheres, com mediana da idade de 56 anos, sendo a área mais procurada a oncologia (23,6%). A área oncológica também foi a que apresentou maiores custos médios. Foi ampla a variedade de doenças geradoras das ações e também foi consequentemente grande a variedade de medicamentos solicitados. Cerca de dois terços dos fármacos foram solicitados pelo nome comercial, e os mais requeridos foram o palivizumabe e brometo de

  3. Influence of seasonal variation on the hydro-biogeochemical characteristics of two upland lakes in the Southeastern Amazon, Brazil.

    PubMed

    Sahoo, Prafulla K; Guimarães, José T F; Souza-Filho, Pedro W M; Silva, Marcio S DA; Silva, Renato O; Pessim, Gustavo; Moraes, Bergson C DE; Pessoa, Paulo F P; Rodrigues, Tarcísio M; Costa, Marlene F DA; Dall'agnol, Roberto

    2016-01-01

    Limnological characteristics of the Violão and Amendoim lakes, in the Serra dos Carajás, Amazon, were studied interannually (2013-2014). Climate data indicate anomalous conditions during the 2013 rainy period with higher rainfall and lower temperature in the beginning (November). Lake levels were influenced after the first and second hour of each rainfall, which showed a strong synchronization between seasonal fluctuation of lake levels and local weather patterns. Based on the water quality, both lakes are classified as classes "1" and "2" in the CONAMA (Conselho Nacional do Meio Ambiente) scheme and as "excellent" to "good" in the WQI (Water Quality Index) categories. However, the limnology is distinctly different between the lakes and seasons. Higher trophic state and phytoplankton productivity were observed mainly during the rainy period in Violão Lake compared to Amendoim Lake. This may be due to deposition of leached nutrients in the former, mainly total phosphorus (TP), which was probably derived from mafic soils and guano. This is consistent with the significant positive correlation between Chlorophyll-a and TP at the end of the rainy period (March-April), whereas this was not observed in the beginning (November). This could possibly be a consequence of the more intense cloud cover, and unusual high rainfall that limits nutrient availability.

  4. Development of the TabacoQuest app for computerization of data collection on smoking in psychiatric nursing.

    PubMed

    Oliveira, Renata Marques de; Duarte, Alexandre Freitas; Alves, Domingos; Furegato, Antonia Regina Ferreira

    2016-08-29

    to develop a mobile app for research on the use of tobacco among psychiatric patients and the general population. applied research with the technological development of an app for data collection on an Android tablet. For its development, we considered three criteria: data security, benefits for participants and optimization of the time of researchers. We performed tests with twenty fictitious participants and a final test with six pilots. the app collects data, stores them in the database of the tablet and export then to an Excel spreadsheet. calculator, stopwatch, offline operation, branching logic, field validation and automatic tabulation. the app prevents human error, increases the quality of the data by validating them during the interview, allows the performing of automatic tabulation and makes the interviews less tiring. Its success may encourage the use of this and other computational resources by nurses as a research tool. desenvolver aplicativo mobile para pesquisa sobre o uso de tabaco entre pacientes psiquiátricos e a população geral. pesquisa aplicada com o desenvolvimento tecnológico de um aplicativo para coleta de dados em tablet Android. Para seu desenvolvimento, consideraram-se três critérios: segurança dos dados, benefícios para os participantes e otimização do tempo dos pesquisadores. Testes com 20 participantes fictícios e teste final com seis pilotos. o aplicativo coleta os dados, armazena-os no banco de dados do tablet e os exporta para planilha Excel. Recursos: calculadora; cronômetro; funcionamento off-line, lógica de ramificação, validação de campos e tabulação automática. o aplicativo previne erros humanos e aumenta a qualidade dos dados ao validá-los durante a entrevista, permite realizar tabulação automática e torna as entrevistas menos cansativas. Seu sucesso poderá incentivar o uso desse e outros recursos computacionais pelos enfermeiros, como ferramenta de pesquisa. desarrollar aplicativo móvil para hacer

  5. Universal Health Coverage through Community Nursing Services: China vs. Hong Kong.

    PubMed

    Chan, Wai Yee; Fung, Ita M; Chan, Eric

    2017-01-30

    this article looks at how the development of community nursing services in China and Hong Kong can enhance universal health coverage. literature and data review have been utilized in this study. nursing services have evolved much since the beginning of the nursing profession. The development of community nursing services has expanded the scope of nursing services to those in need of, not just hospital-level nursing care, but more holistic care to improve health and quality of life. despite the one-country-two-systems governance and the difference in population and geography, Hong Kong and China both face the aging population and its complications. Community nursing services help to pave the road to Universal Health Coverage. este artigo analisa a forma como o desenvolvimento de serviços de enfermagem comunitários na China e Hong Kong pode melhorar a cobertura universal de saúde. literatura e revisão de dados foram utilizados neste estudo. serviços de enfermagem têm evoluído muito desde o início da profissão de enfermagem. O desenvolvimento dos serviços de enfermagem da comunidade ampliou o escopo dos serviços de enfermagem, para aqueles que precisam não apenas de cuidados de enfermagem de nível de hospital, mas cuidados mais holísticos para melhorar a saúde e qualidade de vida. apesar de ser "um-país-dois-sistemas" de governo, e as diferenças de população e geografia, Hong Kong e China enfrentam o envelhecimento da população e suas complicações. Os serviços de enfermagem da comunidade ajudam a pavimentar o caminho para a cobertura de saúde universal. este artículo analiza cómo el desarrollo de los servicios de enfermería comunitaria en China y Hong Kong pueden expandir la cobertura universal de salud. revisión de datos y literatura han sido utilizados en este estudio. los servicios de enfermería han evolucionado mucho desde el comienzo de la profesión. El desarrollo de los servicios de enfermería comunitaria han ampliado el alcance

  6. The Teaching of Astronomy in Uruguay. (Spanish Title: La Enseñanza de la Astronomía en Uruguay.) O Ensino da Astronomia no Uruguai

    NASA Astrophysics Data System (ADS)

    Pintos Ganón, Reina; Fernández, Julio Angel

    2008-07-01

    We present in this work the development of astronomy in Uruguay since the colony times up to the present, stressing in particular those aspects related to the formal as well as informal teaching of astronomy. The first antecedents of astronomical studies in our country go back to the beginnings of the XVIIIth century related to the scientific expeditions from Europe coming to our shores. The teaching of astronomy was generalized at the high school level as soon as the end of the XIXth century, while itsintroduction at the university level happened much later, around the middle of the last century. We analyze the current situation of this subject, its problems, and some measures to strengthen its development. Se presenta en este trabajo el desarrollo de la astronomía en el Uruguay desde la época colonial hasta el presente, destacando en particular los aspectos vinculados a su enseñanza tanto formal como informal. Los primeros antecedentes de estudios astronómicos datan de la época colonial relacionados con las expediciones científicas del Viejo Mundo que llegaban a nuestras costas. La enseñanza de la Astronomía se generalizó en el ámbito de los estudios secundarios ya a fines del siglo XIX, mientras que en la Universidad su arribo fue mucho más tardío, a mediados del siglo pasado. Se analiza la situación actual de esta disciplina, sus problemas, y algunas medidas para fortalecer su desarrollo. Apresentamos, neste trabalho, o desenvolvimento da Astronomia no Uruguai desde a época colonial até o presente, destacando em particular os aspectos vinculados ao seu ensino tanto formal quanto informal. Os primeiros antecedentes de estudos astronômicos em nosso país datam da época colonial relacionados com as expedições científicas do Velho Mundo que chegavam às nossas costas. O ensino da Astronomia se generalizou no âmbito dos estudos secundários já no final do século XIX, enquanto que sua introdução na universidade foi muito mais tardia, em

  7. Diferentes metodologias aplicadas ao ensino de astronomia no Ensino Médio

    NASA Astrophysics Data System (ADS)

    Albrecht, E.; Voelzke, M. R.

    2009-03-01

    O presente trabalho de intervenção foi realizado junto à Escola Estadual Colònia dos Pescadores na cidade de Caraguatatuba, com très turmas do terceiro ano do Ensino Médio, envolvendo 119 alunos com idades entre 16 e 19 anos. A fase inicial foi composta de um questionário de vinte questíes dissertativas e objetivas, aplicado pelo professor titular da sala, que era o mesmo nas très turmas, para diagnosticar nos educandos os conceitos prévios sobre Astronomia e, partindo destes realizar um trabalho de intervenção nas classes envolvidas utilizando, em cada uma, metodologias diferentes: (A) sob forma de seminários, elaborados e apresentados pelos educandos, no qual o educador faz apenas as intervençíes necessárias; (B) de forma tradicional, com auxílio de multimídias para desenvolvimento das aulas e a terceira (C) tradicional, fazendo uso exclusivo de lousa e giz. Ao final do trabalho os alunos responderam novamente o questionário inicial para diagnosticar dentre as très metodologias utilizadas qual apresentou melhores aplicaçíes, os resultados iniciais foram comparados com os finais. Quando questionados a respeito do significado de Astronomia observou-se inicialmente que os acertos na turma A foram de 100%, turma B: 64%, turma C: 84%, após a intervenção os acertos foram: 100%, 97% e 85% respectivamente, demonstrando que houve um avanço significativo na turma B, a turma A manteve seu índice e a turma C evoluiu, porém não tanto quanto a B. Quando interrogados sobre quantos planetas vocè acha que existem em nosso Sistema Solar? os acertos foram: turma A: 39%, turma B: 48% e turma C: 46%, após o desenvolvimento do trabalho os acertos foram 94%, 97% e 90% respectivamente. Dentro das respostas obtidas observa-se que a metodologia tradicional com o auxílio de multimeios, aplicada na turma B, demonstrou melhores resultados, sendo a mais significativa. Outra conclusão muito importante é que apesar de o tema Astronomia ser amplamente

  8. Ensino de Astronomia no Ensino Médio

    NASA Astrophysics Data System (ADS)

    Albrecht, E.; Voelzke, M. R.

    2008-09-01

    O presente trabalho de intervenção foi realizado junto a Escola Estadual Colônia dos Pescadores na cidade de Caraguatatuba, com três turmas do terceiro ano do Ensino Médio, envolvendo 119 alunos, 40 na turma A, 40 na turma B e 39 na turma C. A fase inicial foi composta de um questionário de vinte questões dissertativas e objetivas para diagnosticar nos educandos os conceitos prévios sobre Astronomia e, partindo destes realizar uma interferência nas classes envolvidas utilizando metodologias diferentes sendo elas: a tradicional, onde o professor é um repassador de informações, fazendo uso exclusivo de lousa e giz; a segunda também de forma tradicional, porém com auxílio de multimídia para desenvolvimento das aulas e a terceira sob forma de seminários, elaborados e apresentados pelos educandos, no qual o educador faz apenas as intervenções necessárias. Ao final do trabalho as mesmas turmas da fase inicial orientadas pelo mesmo professor responderam novamente ao questionário proposto para diagnosticar dentre as três metodologias utilizadas qual apresentou melhores resultados, sendo os iniciais comparados com os finais. Quando questionados a respeito do significado de Astronomia observou-se inicialmente que os acertos na turma A foram de 100%,turma B: 64%, turma C: 84%, após a intervenção os acertos foram: 100%, 97% e 85% respectivamente, demonstrando claramente uma absorção de conhecimentos. Quando interrogados sobre quantos planetas você acha que existem em nosso Sistema Solar? os acertos foram: turma A: 39%, turma B: 48% e turma C: 46%, após o desenvolvimento do trabalho os acertos foram 94%, 97% e 90% respectivamente.Dentro das respostas obtidas observa-se que a metodologia tradicional com o auxílio de multimeios, aplicada na turma B, demonstrou melhores resultados, foi a mais significativa.

  9. Health, development and innovation: a contribution of the critical theory of technology to the discussion.

    PubMed

    Souza, Luis Eugenio Portela Fernandes de

    2016-11-03

    The relationships between health and socioeconomic development are diverse. These relationships find in the health economic complex a privileged ground for expression. The importance of health technologies increased exponentially since the middle of the 20th century, affecting health systems in terms of both, quality of care and economic aspects. In fact, the predominant model of care is based on fragmented, symptomatic therapy practices that encourages the use of products and services and promotes a passive participation of users rather than humanization of care. Overcoming this model requires changes in the health technology standards which, in turn, require changes in the technology standard of society. The critical theory of technology helps to understand the evolution of the industrial civilization. It enriches the discussion by suggesting the health economic complex be more sensibly adjusted to the requirements of comprehensive health care, and to inclusive and sustainable development. Resumo: As relações entre a saúde e o desenvolvimento socioeconômico são múltiplas. Essas relações têm o complexo econômico da saúde como o espaço privilegiado de sua expressão. A importância das tecnologias de saúde aumentou exponencialmente desde meados do século XX, com efeitos sobre os sistemas de saúde, tanto em qualidade da atenção, quanto em aspectos econômicos. Na realidade, predomina um modelo de atenção caracterizado por práticas fragmentadas, que enfatizam tratamentos sintomáticos, estimulam o consumismo de produtos e serviços e promovem, ao invés da humanização, uma participação passiva dos usuários. A superação desse modelo passa pela mudança do padrão tecnológico da saúde, que, por sua vez, exige a transformação do padrão tecnológico da sociedade. A teoria crítica da tecnologia ajuda a compreender a evolução da civilização industrial. Enriquece o debate, sugerindo uma conformação do complexo econômico da saúde mais

  10. Water fluoridation in Brazilian cities at the first decade of the 21st century.

    PubMed

    Frazão, Paulo; Narvai, Paulo Capel

    2017-05-15

    To assess the coverage of the fluoridation of the public water supply in Brazilian municipalities at the first decade of the 21st century, according to population size and municipal human development index (MHDI). We have used data produced by national information agencies and the United Nations Development Programme. Population size was separated into < 10,000, 10,000-50,000, and > 50,000 inhabitants. The MHDI was classified into < 0.600, 0.600-0.699, 0.700-0.799, and > 0.799. Absolute and relative inequalities between categories were evaluated using indicators of effect and total impact. We have obtained information for 5,558 municipalities. The coverage rate of water fluoridation increased from 67.7% to 76.3%. Approximately 884 (15.9%) municipalities and 29,600,000 inhabitants started being benefited by the measure. We have observed a significant expansion in municipalities with < 10,000 inhabitants (increase of 21.0 percentage points) and low or very low MHDI (17.7 percentage points). Population coverage of the public policy has increased 8.6%, and we can also see significant reductions in absolute and relative inequality according to population size and MHDI. Regarding municipal coverage rate, there was also a reduction in inequality in all comparisons except for absolute inequality between the categories of MHDI. The public policy has operated as a factor of health protection in the context of the ongoing social protection policies in the country. Avaliar a cobertura da fluoretação da água de abastecimento público em municípios brasileiros na primeira década do século XXI, segundo porte demográfico e nível de desenvolvimento humano municipal (IDH-M). Foram utilizados dados produzidos por agências nacionais de informação e pelo Programa das Nações Unidas para o Desenvolvimento. O porte demográfico foi separado em < 10 mil; 10-50 mil; > 50 mil habitantes. O IDH-M foi classificado em < 0,600; 0,600-0,699; 0,700-0,799; > 0,799. As desigualdades

  11. Osteoporosis: from bone biology to individual treatment decision.

    PubMed

    Gonçalves, Maria João; Rodrigues, Ana Maria; Canhão, Helena; Fonseca, João Eurico

    2013-01-01

    Introdução: A Osteoporose é uma doença óssea metabólica sistémica de prevalência crescente. Nesta revisão, abordamos os mais recentes estudos epidemiológicos e o seu impacto no tratamento individual dos doentes, assim como os mecanismos moleculares desta doença que levaram à descoberta de novos alvos terapêuticos.Material e Métodos: Usando os MeSH terms (osteoporose, epidemiologia, Portugal, Europa, patogenia, osteoblastos, osteoclastos, osteócitos, obesidade, sistema imune, terapia, ensaio randomizado e controlado, eficácia e segurança) como palavras-chave. Foram revistos artigos originais, revisões e position papers indexados na PubMed.Resultados: A osteoporose apresenta uma prevalência crescente, mas recentemente foi atingido um plateau na taxa ajustada à idade. Uma nova ferramenta, o FRAX™, foi desenvolvida para a estimativa do risco de fratura, a partir da contribuição de fatores de risco clínicos associados a fraturas de fragilidade. O tratamento da osteoporose é oferecido a uma baixa percentagem de doentes com osteoporose. O tratamento em 40% dos casos inicia-se já em doença estabelecida (na presença de fratura de fragilidade prévia). As questões de segurança associadas a medicamentos para tratamento da Osteoporose, após aprovação para comercialização, têm sidoalvo de debate. Por último, os avanços no entendimento da biologia molecular do metabolismo ósseo levaram ao desenvolvimento de novas drogas.Discussão e Conclusão: Apesar da existência de novas ferramentas diagnósticas e tratamento eficaz, o tratamento para osteoporose é oferecido a uma minoria dos doentes, muitas vezes a indivíduos com doença avançada. A mudança deste cenário poderá ser alcançada com novos e mais eficazes tratamentos.

  12. Adverse events with the influenza A(H1N1) vaccine Pandemrix® at healthcare professionals in Portugal.

    PubMed

    Marques, Joana Isabel; Ribeiro Vaz, Inês; Santos, Cristina; Polónia, Jorge

    2013-01-01

    Introdução: Os profissionais de saúde foram um grupo prioritário para vacinação contra a pandemia da Gripe A (H1N1), Pandemrix®. Assim, monitorizar os eventos adversos relacionados com esta vacina neste grupo específico poderá originar informação valiosa relacionada com o perfil de segurança da vacina. O nosso objetivo foi identificar os eventos adversos após imunização com a vacina Pandemrix® em profissionais de saúde. Material e Métodos: Foi desenhado um questionário de monitorização dos eventos adversos ocorridos com a vacina Pandemrix®. O questionário foi distribuído aos profissionais de saúde a trabalhar em três centros hospitalares da região norte do País, vacinados no período de 26 de Outubro de 2009 a 31 de janeiro de 2009. Resultados: Dos 2358 profissionais de saúde que aceitaram participar no estudo, 864 (37%) devolveram o questionário preenchido. Destes, 73% experienciaram pelo menos um evento adverso após imunização, mas só 8% experienciaram um evento inesperado. Os eventos adversos mais frequentemente reportados foram os esperados e muito comuns: reações locais no local de administração (57%), mialgia (31%), fadiga (incluindo astenia) (24%) e dor de cabeça (19%). Não foram reportados casos de eventos de maior gravidade para a saúde, tais como morte ou risco de vida. O género feminino e a existência de doença de base foram fatores de risco independentes para o desenvolvimento de pelo menos um evento adverso após imunização com a Pandemrix®. Conclusões: O nosso trabalho sugere um perfil de segurança aceitável da vacina pandémica Pandermix® em profissionais de saúde. Tanto a frequência como a severidade dos eventos adversos não se verificaram superiores ao esperado.

  13. Cosmoeducação: uma proposta para o ensino de astronomia

    NASA Astrophysics Data System (ADS)

    Medeiros, L. A. L.; Jafelice, L. C.

    2003-08-01

    Entende-se por cosmoeducação o desenvolvimento vivencial da unidade homem-cosmo. Este conceito é norteado pela psicologia transpessoal, que estuda o ser humano em sua totalidade, onde suas relações ecológicas e cósmicas são de grande importância. Constata-se uma necessidade latente no ser humano moderno em resgatar uma relação holística com o Universo. Neste trabalho exploramos meios de cultivar a consciência de que o ser humano constitui parte integrante do cosmo e se relaciona com este com o objetivo de promover em si uma percepção ambiental mais ampla. Nossa hipótese de trabalho inicial foi que o ensino de conteúdos básicos em astronomia realizado através de uma abordagem holística, que incorpore práticas vivenciais correlacionadas àqueles conteúdos, pode despertar no indivíduo sua identidade cósmica. O método que utilizamos é o fenomenológico e o universo desta pesquisa é um grupo de estudantes da disciplina de Astronomia (Curso de Licenciatura em Geografia/UFRN), onde realizamos observação participante, entrevistas, depoimentos e as práticas vivenciais mencionadas. Neste caso estamos desenvolvendo e adaptando exercícios de algumas técnicas terapêuticas de psicologia transpessoal, que um de nós (LALM) tem aplicado no contexto clínico, para trabalhar aspectos cognitivos envolvidos naquele processo de conscientização cósmica. Resultados parciais claramente referendam a hipótese inicial. Um resultado a destacar é fruto de uma dinâmica de representação corporal interiorizada do eclipse lunar, envolvendo um pequeno grupo daqueles estudantes, na qual conteúdos míticos afloraram de maneira espontânea e contundente para todos, sugerindo ressonância, ou pelo menos isomorfismo, entre o macro e o microcosmo. Este e outros resultados são discutidos em detalhe neste trabalho. (PPGECNM/UFRN; PRONEX/FINEP; NUPA/USP; Temáticos/FAPESP).

  14. Ada Compiler Validation Summary Report: Certificate Number: 901120W1. 11088 R.R. Software, Inc., Janus/Ada 2.2.0 PHAR Lap/DOS, IBM PS/2, MOD. 80 Phar Lap/DOS 3.3 (Host and Target)

    DTIC Science & Technology

    1991-08-01

    first the source disk, then the dufault disk, and then the swap disk unill’all of the units are found (or the linker Is aborted by the user). The...same path its filinduiCl. •Spath Use the specified path as the swap disk. The linker will abort if aU of the libraries needed In the current pogrmzn are...swap disk. The linking may be aborted at any time during a swap, The swap disk may not be ihe same as the destination disk Any other peth n ay be used

  15. Quality of nursing documentation before and after the Hospital Accreditation in a university hospital.

    PubMed

    Nomura, Aline Tsuma Gaedke; Silva, Marcos Barragan da; Almeida, Miriam de Abreu

    2016-11-21

    to analyze the quality of nursing documentation by comparing the periods before and after the preparation for the hospital accreditation, using the Quality of Nursing Diagnoses, Interventions and Outcomes - Brazilian version (Q-DIO- Brazilian version). observational study of interventions conducted in a university hospital. Nursing documentation of 112 medical records for the period before and 112 for the period after the hospital accreditation were compared using the Q-DIO instrument - Brazilian version. Data were statistically analyzed. there was a significant improvement in the quality of nursing documentation. When the total score of the instrument was evaluated, a significant improvement was observed in 24 out of the 29 items (82.8%). there was commitment to the shift of culture by means of the interventions carried out, which resulted in the conquest of the quality seal ensured by the Joint Commission International. analisar a qualidade dos registros de enfermagem, comparando o período antes e depois do preparo para a acreditação hospitalar, fazendo uso do Quality of Nursing Diagnoses, Interventions and Outcomes - Versão brasileira (Q-DIO-Versão brasileira). estudo observacional de intervenções realizado em um hospital universitário. Comparados os registros de enfermagem em 112 prontuários referentes ao período anterior a acreditação hospitalar e 112 ao período posterior, por meio do instrumento Q-DIO - Versão brasileira. Os dados foram analisados estatisticamente. houve melhora significativa da qualidade dos registros de enfermagem. Quando avaliado o escore total do instrumento evidenciou melhora significativa em 24 dos 29 itens (82,8%). houve empenho à mudança de cultura por meio das intervenções realizadas, refletida na conquista do selo de qualidade da Joint Commission Internacional. analizar la calidad de los registros de enfermería, comparando los períodos antes y después de la preparación para la acreditación hospitalaria

  16. Disparities in cancer epidemiology and care delivery among Brazilian indigenous populations.

    PubMed

    Aguiar, Pedro Nazareth; Stock, Gustavo Trautman; Lopes, Gilberto de Lima; Almeida, Michelle Samora de; Tadokoro, Hakaru; Gutierres, Bárbara de Souza; Rodrigues, Douglas Antônio

    2016-01-01

    To assess aspects related to cancer in indigenous population. This is a retrospective study developed in a public university hospital. We included patients with 18 or more years of age, diagnosed with solid tumors, and followed between 2005 and 2015. Clinical features were assessed by descriptive statistics, and survival was evaluated by Kaplan-Meier curves and multivariate Cox regression. Fifty patients were included. The cancer incidence was 15.73 per 100,000. The mean age at diagnosis was 54 years and most patients were female (58%). Cancer of the cervix (28%) and prostate (16%) were the most common. The mean time between the onset of symptoms and the diagnosis was 9 months and from diagnosis to the treatment was 3.4 months. Disease diagnosed at stage IV (17%) had worse overall survival (HR: 11.4; p<0.05). The 5-year survival rate ranged from 88% for prostate cancer to 0% for lung cancer. All 5-year survival rates were lower as compared to other populations. The most prevalent cancer sites were cervix and prostate. Disease stage and primary site were prognostic factors. Avaliar os aspectos relacionados a câncer em populações indígenas. Estudo retrospectivo conduzido em um hospital universitário público. Foram incluídos pacientes com 18 anos ou mais, diagnosticados com tumores sólidos e acompanhados entre 2005 e 2015. Os aspectos clínicos foram avaliados por meio de estatística descritiva, e a sobrevida foi avaliada por meio de curvas de Kaplan-Meier e regressão multivariada de Cox. Foram incluídos 50 pacientes. A incidência de câncer foi 15,73 por 100 mil. A média de idade ao diagnóstico foi 54 anos, e a maioria era do sexo feminino (58%). O câncer de colo uterino (28%) e o de próstata (16%) foram os mais frequentes. O tempo médio entre o início dos sintomas e o diagnóstico foi 9 meses, e entre o diagnóstico e o tratamento, de 3,4 meses. Doença diagnosticada no estágio IV (17%) resultou em pior sobrevida global (HR: 11,4; p<0,05). A

  17. Violence against children and adolescents: the perspective of Primary Health Care.

    PubMed

    Carlos, Diene Monique; Pádua, Elisabete Matallo Marchesini de; Ferriani, Maria das Graças Carvalho

    2017-01-01

    To analyze the care provided by Basic Health Units (BHU) to families involved in domestic intrafamily violence against children and adolescents. Qualitative research, based on the Paradigm of Complexity. Data collection was performed with 41 professionals through focus groups and semi-structured interviews. The following categories emerged from data analysis: 'Everything comes here', which reflects the legitimate place of BHUs for the population and the actions taken to build care for families; and 'We only do what is really necessary', which brings the look to violence still based on the positivist and biomedical paradigm. The model of understanding and construction of work processes in the BHU is structured in the aforementioned paradigm. Nurses have the possibility to become agents of change, both in professionals' training and in the care thought and provided to communities. Analisar o cuidado realizado por Unidades Básicas de Saúde (UBS) junto a famílias envolvidas na violência intrafamiliar contra crianças e adolescentes. Pesquisa qualitativa, fundamentada no Paradigma da Complexidade. A coleta de dados foi realizada com 41 profissionais, por meio de grupos focais e entrevistas semiestruturadas. Da análise dos dados, emergiram as seguintes categorias: "Tudo desemboca aqui", que reflete o lugar legitimado das UBSs para a população e as ações realizadas para construção do cuidado às famílias; e "A gente só faz o que é indispensável mesmo", que traz o olhar para a violência ainda pautado no paradigma positivista e biomédico. O modelo de compreensão e construção dos processos de trabalho na UBS é estruturado no último paradigma citado. O enfermeiro tem a possibilidade de se colocar como um agente de mudanças, tanto na formação dos profissionais quanto no cuidado pensado e executado junto às comunidades.

  18. Spiritual well-being and quality of life of older adults in hemodialysis.

    PubMed

    Pilger, Calíope; Santos, Renata Ohana Pereira Dos; Lentsck, Maicon Henrique; Marques, Sueli; Kusumota, Luciana

    2017-01-01

    To analyze the relationship between spiritual well-being, sociodemographic, economic, religious, and health variables and the quality of life of older adults undergoing hemodialysis. This was a cross-sectional and correlational study conducted with 169 older adults undergoing hemodialysis. The researchers conducted interviews to collect sociodemographic, economic, religious, and health data and applied the Spiritual Well-Being Scale (SWBS) and the WHO quality of life assessment (WHOQOL-BREF and WHOQOL-OLD). Most of the older adults attained a moderate level of total spiritual well-being (SWB). In terms of QOL, the psychological domain (66.8; sd=13.9) and social relationships domain (66.8; sd=15.1) presented the highest mean scores. The WHOQOL-BREF domains were positively correlated with the SWB scale, with statistical significance among all domains and subscales except the environmental domain. The QOL of older adults was associated with the construct of SWB, either positively or negatively. Analisar a relação entre o bem-estar espiritual, variáveis sociodemográficas, econômicas, religiosas e de saúde com a qualidade de vida de idosos em tratamento hemodialítico. Estudo transversal e correlacional feito com 169 idosos que realizavam hemodiálise. Foram realizadas entrevistas para caracterização sociodemográfica, econômica, religiosa e de saúde, além de aplicação da Escala de Bem-Estar Espiritual (EBE) e de Qualidade de vida (QV) (WHOQOL- bref e WHOQOL - Old). A maioria dos idosos possuía moderado bem-estar espiritual total (EBE). Com relação à QV, os domínios psicológico (66,8; dp=13,9) e relações sociais (66,8; dp=15,1) apresentaram os maiores escores médios. A correlação dos domínios do WHOQOL- bref com os escores da escala de EBE foi positiva, com significância estatística em todos os domínios e nas subescalas, exceto no domínio meio ambiente. A QV dos idosos está relacionada, seja de forma positiva ou negativa, com o constructo

  19. Nursing care by telehealth: what is the influence of distance on communication?

    PubMed

    Barbosa, Ingrid de Almeida; Silva, Maria Júlia Paes da

    2017-01-01

    Evaluate the perception of nurses regarding interpersonal communication while providing care via telehealth. Qualitative research realized with seven nurses working in telehealth in Brazil, the sample was determined by data saturation. A questionnaire with open questions was applied and then content analysis of the dialogues was conducted, focusing on thematic analysis. Four categories emerged from the dialogues: Understanding the importance of communication; the interpersonal relationship interfering with communication; Communicating via technology; and Learning the communication process. The perception of nurses working in telehealth in Brazil is that technology has facilitated their professional practice; however, in relation to the communication process, they believe it is harder to communicate by telehealth, mainly due to difficulty in perceiving nonverbal signals. To overcome these difficulties, they agreed that interpersonal communication is a skill that must be acquired during their professional training. Avaliar a percepção do enfermeiro referente à Comunicação interpessoal no cuidado por telessaúde. Pesquisa qualitativa, realizada com sete enfermeiros que atuam em telessaúde no Brasil, com amostra determinada pela saturação de dados. Aplicou-se um questionário com perguntas abertas e foi realizada análise de conteúdo dos discursos, com enfoque na análise temática. Dos discursos emergiram quatro categorias: Entendendo a importância da comunicação; O relacionamento interpessoal interferindo na comunicação; Comunicando-se por meio da tecnologia; e Aprendendo o processo de comunicação. A percepção dos enfermeiros que atuam em telessaúde no Brasil é de que a tecnologia tem facilitado sua prática profissional; porém, em relação ao processo de comunicação, creem que seja mais difícil se comunicar pela telessaúde, principalmente devido à dificuldade de percepção de sinais não verbais. Para superar essas dificuldades, concordam

  20. Teamwork in a coronary care unit: facilitating and hindering aspects.

    PubMed

    Goulart, Bethania Ferreira; Camelo, Silvia Helena Henriques; Simões, Ana Lúcia de Assis; Chaves, Lucieli Dias Pedreschi

    2016-01-01

    To identify, within a multidisciplinary team, the facilitating and hindering aspects for teamwork in a coronary care unit. A descriptive study, with qualitative and quantitative data, was carried out in the coronary care unit of a public hospital. The study population consisted of professionals working in the unit for at least one year. Those who were on leave or who were not located were excluded. The critical incident technique was used for data collection, by means of semi-structured interviews. For data analysis, content analysis and the critical incident technique were applied. Participants were 45 professionals: 29 nursing professionals; 11 physicians; 4 physical therapists; and 1 psychologist. A total of 49 situations (77.6% with negative references); 385 behaviors (54.2% with positive references); and 182 consequences emerged (71.9% with negative references). Positive references facilitate teamwork, whereas negative references hinder it. A collaborative/communicative interprofessional relationship was evidenced as a facilitator; whereas poor collaboration among agents/inadequate management was a hindering aspect. Despite the prevalence of negative situations and consequences, the emphasis on positive behaviors reveals the efforts the agents make in order to overcome obstacles and carry out teamwork. Identificar, junto à equipe multiprofissional, aspectos facilitadores e dificultadores do trabalho em equipe em Unidade Coronariana. Estudo descritivo, com dados qualitativos e quantitativos, realizado em Unidade Coronariana/Hospital público. População constituída de profissionais atuantes na Unidade há, pelo menos, um ano. Excluídos os afastados do trabalho e os que não foram não localizados. Para a coleta de informações, utilizou-se da Técnica do Incidente Crítico por meio de entrevista semiestruturada. Para a análise dos dados, utilizaram-se da Análise de Conteúdo e Técnica do Incidente Crítico. Participaram 45 profissionais: 29

  1. Promoting oral care in the preschool child: effects of a playful learning intervention.

    PubMed

    Sigaud, Cecília Helena de Siqueira; Santos, Bruna Rodrigues Dos; Costa, Priscila; Toriyama, Aurea Tamami Minagawa

    2017-01-01

    To compare the number of appropriate behaviors for tooth brushing before and after a playful learning intervention with preschool children. A quasi-experimental, quantitative, before and after study design was conducted in an early childhood educational institution, with children between three and five years of age. The intervention consisted of three meetings with educational activities about tooth brushing, whose outcome was evaluated by means of observation of ten behaviors suitable for tooth brushing. Forty-four children participated in the study. The mean of adequate behaviors was 4.4 before the intervention, and 8.5 after the intervention. A significant increase in the adoption of appropriate behaviors for tooth brushing (p <0.01) was identified. Nurses can enhance oral health promotion actions with preschoolers in preschool institution using playful learning interventions. Comparar o número de comportamentos adequados para a escovação de dentes antes e após uma intervenção educativa lúdica com pré-escolares. Estudo quase-experimental, do tipo antes-depois, com abordagem quantitativa e conduzido em instituição de educação infantil com crianças entre três e cinco anos de idade. A intervenção consistiu em três encontros com atividades educativas lúdicas sobre escovação de dentes, cujo efeito foi avaliado por meio da observação de dez comportamentos adequados para a escovação dos dentes. Participaram do estudo 44 crianças. A média de comportamentos adequados foi de 4,4 antes da intervenção e 8,5 após a mesma. Houve um aumento significativo na adoção de comportamentos adequados para a escovação de dentes (p < 0,01). Por meio de intervenções educativas lúdicas, recomenda-se que os enfermeiros potencializem as ações de promoção da saúde bucal com pré-escolares em instituições de educação infantil.

  2. Paradox of life among survivors of bladder cancer and treatments.

    PubMed

    Lopes, Miriam; Nascimento, Lucila Castanheira; Zago, Márcia Maria Fontão

    2016-04-01

    To interpret the meanings attributed to the experience of bladder cancer among survivors in therapeutic follow-up. Qualitative methodological approach, based on medical anthropology and narrative methodology. After approval by the research ethics committee of a public university hospital, data were collected from January 2014 to February 2015, by means of recorded semi-structured interviews, direct observation and field journal entries on daily immersion with a group of six men and six women, aged between 57 and 82 years, in therapeutic follow-up. Narratives were analyzed by means of inductive thematic analysis. The meanings revealed difficulties with the processes of disease and treatment, such as breakdown of normal life, uncertainty about the future due to possible recurrence of the disease, difficulty with continuity of care and emotional control, relating it to conflicting ways of understanding the present life. Thus, the meaning of this narrative synthesis is paradox. Interpretation of the meaning of experience with bladder cancer among patients provides nurses with a comprehensive view of care, which encompasses biological, psychological and social dimensions, and thereby systematizes humanized care. Interpretar o significado atribuído à experiência do câncer de bexiga entre sobreviventes em seguimento terapêutico. Empregou-se a abordagem metodológica qualitativa, embasado pela antropologia médica e método narrativo. Após aprovação do Comitê de Ética, os dados foram coletados de janeiro 2014 a fevereiro de 2015, por meio de entrevistas semiestruturadas gravadas, observação direta e registros no diário de imersão com grupo de seis homens e seis mulheres, entre 57 e 82 anos, em seguimento terapêutico em um hospital público universitário. As narrativas foram analisadas por meio da análise temática indutiva. Os sentidos revelam as dificuldades com o processo da doença e do tratamento, como rupturas na vida, futuro incerto pela

  3. Melhoramentos no código Wilson-Devinney para binárias eclipsantes

    NASA Astrophysics Data System (ADS)

    Vieira, L. A.; Vaz, L. P. R.

    2003-08-01

    A análise de curvas de luz e velocidades radiais de sistemas binários eclipsantes pode ser feita por meio de vários modelos. Um desses é o Modelo Wilson-Devinney (WD). Ao longo dos anos, esse modelo sofreu várias alterações em seus códigos principais, com a finalidade de torná-lo mais consistente tanto fíisica como numericamente. O Modelo WD tem sido melhorado de várias maneiras em seus dois códigos: um para a predição das curvas de luz teórica e de velocidade radiais e outra para as soluções destas curvas. Teoricamente, na física do modelo, nós introduzimos a possibilidade de levar em conta os efeitos do movimento apsidal. Numericamente, nós introduzimos a possibilidade de usar o Método SIMPLEX no procedimento da solução, como uma alternativa para o já implementado Método de Mínimos Quadrados (Least Squares Method). Estas modificações, juntamente com outras já introduzidas pelo nosso grupo anteriormente, tornam o código mais eficiente na solução das curvas de luz e de velocidade radiais de binárias eclipsantes. Como o modelo tem sido usado para analisar sistemas com componentes pré-sequência principal (TY CrA, Casey et al. 1998, Vaz et al. 1998), SM 790, Stassun et al. 2003), este melhoramento beneficiará estes casos também. Apresentamos os resultados obtidos com a modificação do código WD por meio do uso de dados da estrela GL Carinae, comprovando, (1) que os parâmetros orbitais calculados por nós são coerentes com os obtidos anteriormente na literatura (Giménez & Clausen, 1986) e com os obtidos por Faria (1987), e (2) que a implementação do Método SIMPLEX torna o código mais lento mas completamente consistente internamente e evita os problemas gerados pelo uso do Método de Mínimos Quadrados, tais como imprecisão no cálculo das derivadas parciais e convergência para mínimos locais.

  4. A teoria da percolação aplicada às galáxias aneladas peculiares

    NASA Astrophysics Data System (ADS)

    Poppe, P. C. R.; Martin, V. A. F.; de Medeiros, N. G. F.; Faúndez-Abans, M.; Oliveira-Abans, M.

    2003-08-01

    Formulado no final da década de 50, o modelo de percolação concentra-se em descrever o meio poroso, que será visto neste trabalho como uma rede de canais aleatórios, por onde escoa um fluido determinístico. Se o número de canais for suficientemente grande, então eles estarão ligados e o meio se tornará permeável à passagem do fluido. Neste caso, dizemos que houve a percolação do fluido. Reformulando o modelo acima, podemos escrever um código particularmente adaptado para simulações em Galáxias, onde iremos supor que os canais formam um reticulado, e que cada sítio da rede representa um poro que será interpretado como uma região ativa de formação estelar. Para cada elo teremos um pequeno canal ligando dois sítios vizinhos, que poderá, após um tempo "t", induzir ou não a formação de uma região ativa no poro vizinho. Para simular a passagem desta região ativa através dos poros, diremos que um elo está aberto com probabilidade p e fechado com probabilidade 1-p. Dessa forma, passamos a imaginar configurações de elos abertos e fechados, onde cada configuração ocorre com uma certa probabilidade, dada por p|A|(1-p)|F|, onde |A| é o número de elos abertos e |F| o número de elos fechados da configuração. A expressão anterior só tem importância física se |A| e |F| forem ambos finitos, pois, caso contrário, a probabilidade de ocorrência de uma dada configuração será sempre nula. Neste trabalho, foram considerados dados cinemáticos publicados na literatura bem como aqueles obtidos pelos autores a partir de observações fotométricas realizadas no Observatório de Las Campanãs, em 1994, para a Galáxia Anelada Peculiar HRG 03401. Mostraremos que para certos valores de p, situados entre 0,5 e 0,6, os clusters assim formados irão simular, de maneira coerente, o referido objeto.

  5. Transection of the hepatic parenchyma associated or not with the contralateral portal vein branch ligature and its effect in liver regeneration.

    PubMed

    Wiederkehr, Henrique de Aguiar; Wiederkehr, Julio Cesar; Collaço, Luiz Martins; Sousa, Eros Luiz de; Salvalaggio, Paolo; Carvalho, Caroline Aragão de; Wiederkehr, Barbara de Aguiar; Marques, Camila Aparecida Moraes; Rosa, Francielle França da; Nanni, Felipe de Negreiros; Fuchs, Taíse

    2017-01-01

    To analyze the influence of portal vein ligation in hepatic regeneration by immunohistochemical criteria. Ten pigs divided into two groups of five animals underwent hepatectomy in two stages, and the groups were differentiated by ligation or not of the left portal vein tributary, which is responsible for vascularization of the left lateral and medial lobes of the pig liver. Five days after the procedure, the animals underwent liver biopsies for further analysis of histological and immunohistochemical with marker Ki67. The group submitted to hepatectomy with vascular ligation showed an increase of approximately 4% of hepatocytes in regeneration status, as well as a greater presence of Kupffer and inflammatory cells as compared to control. As a result of positive cell replication observed through the Ki67 marker, we can suspect that the ligation of a tributary of the portal vein associated with liver resection promoted a greater stimulus of liver regeneration when compared to liver resection alone. Analisar a influência da ligadura da tributária da veia porta no estímulo regenerativo hepático por meio de critérios imuno-histoquímicos. Dez suínos, divididos em dois grupos de cinco animais, foram submetidos à hepatectomia em dois estágios, sendo que os grupos foram diferenciados pela ligadura ou não da tributária da veia porta, responsável pela vascularização dos lobos lateral e medial esquerdos do fígado do suíno. Cinco dias após o procedimento, os animais foram reabordados para retirada de amostras hepáticas para posterior análise de histológica e imunoistoquímica com o marcador Ki67. O grupo submetido à hepatectomia com ligadura vascular apresentou incremento de 4% aproximadamente de hepatócitos em processo de regeneração, bem como grande número de células de Kupffer e células inflamatórias, quando comparado ao controle. Em virtude da análise positiva da replicação celular observada por meio do marcador Ki67, pode-se observar que a

  6. Abundâncias de oxigênio e enxofre nas estrelas de tipo solar da vizinhança solar

    NASA Astrophysics Data System (ADS)

    Requeijo, F.; Porto de Mello, G. F.

    2003-08-01

    Alguns resultados sugerem que o Sol seja 58% mais abundante em oxigênio que o meio interestelar local. Esta anomalia parece estender-se para o carbono e o criptônio. Entre as possíveis explicações deste fenômeno estão: uma supernova de tipo II que tenha enriquecido a nebulosa protosolar, tornando-a superabundante em oxigênio; um episódio de infall de material pobre em metais sobre o disco Galático, diluindo o meio interestelar local ou uma migração dinâmica do Sol de uma órbita mais interna da Galáxia para sua posição atual. A escolha entre estes cenários exige o conhecimento preciso da abundância solar em relação às anãs G da vizinhança. Neste contexto, o oxigênio e enxofre, são elementos-chave por serem ambos produzidos pelas supernovas de tipo II, devendo portanto possuir o mesmo padrão de abundância. Este projeto visa esclarecer qual a posição do Sol na distribuição local de abundâncias de enxofre e oxigênio para uma amostra de estrelas de tipo solar com idades e metalicidades bem conhecidas. Para tal, analisamos espectros de alta resolução e alta relação sinal-ruído nas regiões espectrais de ll 6300, 7774 (O) e l8695 (S). Para o enxofre encontramos que o Sol parece ser uma estrela típica dentre as da vizinhança, e que este elemento não mostra a sobreabundância para baixas metalicidades, já bem estabelecida para o oxigênio. Discutimos as abundâncias do enxofre no contexto da Evolução Química da Galáxia. Apresentamos resultados preliminares muito precisos para a linha proibida do oxigênio l6300 e comparamos estes com os obtidos para o tripleto em l7774. Quantificamos os efeitos não-ETL presentes no tripleto em função dos parâmetros atmosféricos estelares.

  7. Chronic hepatitis B and D: prognosis according to Child-Pugh score.

    PubMed

    Oliveira, Marcelo Siqueira de; Silva, Romeu Paulo Martins; Valle, Suiane da Costa Negreiros do; Figueiredo, Elisabeth Níglio de; Fram, Dayana

    2017-01-01

    compare chronic hepatitis B patients to those superinfected with hepatitis D virus, according to Child-Pugh score regarding disease severity. retrospective descriptive study, performed with 59 patients followed in the ambulatory, of which 22 (37.3%) were chronically infected with hepatitis B virus (Group HBV) and 37 (62.7%) superinfected with Delta virus (Group HBV+HDV); variables of sex, age and items of Child-Pugh score were collected by consulting medical records. out of the patients, 57.6% were male, with a mean age of 30.5 years. Score A, which indicates lesser severity, was found in 100% of group HBV and 78.4% of group HBV+HDV. Score B, which indicates greater severity, was found only in group HBV+HDV in 21.6% of the patients. by means of the Child-Pugh score, it was observed that patients with superinfection by HDV tended to present a worse prognosis. comparar os pacientes com hepatite B crônica com superinfectados pelo vírus D segundo escore de Child-Pugh quanto à gravidade da doença. estudo descritivo retrospectivo, realizado com 59 pacientes acompanhados em ambulatório, sendo 22 (37,3%) cronicamente infectados pelo vírus da hepatite B (Grupo VHB) e 37 (62,7%) com superinfecção por vírus Delta (Grupo VHB+VHD); foram coletadas variáveis quanto ao sexo, idade e referentes ao escore de Child-Pugh por meio de consulta a prontuários. entre os pacientes 57,6% era do sexo masculino, com idade média de 30,5 anos. O escore A, que indica menor gravidade, foi encontrado em 100% do grupo VHB e 78,4% do grupo VHB+VHD. O escore B, que indica maior gravidade, foi encontrado apenas no grupo VHB+VHD em 21,6% dos pacientes. por meio do escore de Child-Pugh, observou-se que os pacientes com superinfecção por VHD tendem a apresentar pior prognóstico.

  8. Stress and optimism of elderlies who are caregivers for elderlies and live with children.

    PubMed

    Oliveira, Nathalia Alves de; Souza, Érica Nestor; Luchesi, Bruna Moretti; Inouye, Keika; Pavarini, Sofia Cristina Iost

    2017-01-01

    to evaluate the relation between stress and optimism of elderlies who are informal caregivers for elderlies and live with children. cross-sectional study on 50 elderlies who provide care to elderlies, live with children, and are registered in the primary health care. The interviews occurred in the participant's residence and we evaluated characteristics of the care-dependent elderly and of the children, sociodemographic characteristics, stress through the Perceived Stress Scale and optimism through the Pinto and Pais-Ribeiro Spirituality Scale, in the elderly caregiver. For statistical analysis we used the Spearman correlation test. the mean level of stress was 23.9 points and of optimism was 3.3 points. Correlation analysis showed that the higher the level of optimism the significantly lower the level of perceived stress of elderlies who provided care to elderlies and lived with children. inversely proportional correlation was identified between stress and optimism. avaliar a relação entre estresse e otimismo de idosos cuidadores informais de idosos e que residem com crianças. Método: estudo transversal com 50 idosos cuidadores de idosos que residem com crianças e são cadastrados na atenção básica. As entrevistas ocorreram no domicílio do participante e foram avaliadas características do idoso dependente de cuidados e das crianças, características sociodemográficas, estresse por meio da Escala de Estresse Percebido e o otimismo por meio da Escala de Espiritualidade de Pinto e Pais-Ribeiro, no idoso cuidador. Para análise estatística foi utilizado o teste correlação de Spearman. o nível médio de estresse foi de 23,9 pontos e de otimismo foi de 3,3 pontos. A análise de correlação mostrou que quanto maior o nível de otimismo significativamente menor foi o nível de estresse percebido dos idosos cuidadores de idosos que residiam com crianças. foi identificada correlação inversamente proporcional entre estresse e otimismo.

  9. Integrality of care: challenges for the nurse practice.

    PubMed

    Sousa, Solange Meira de; Bernardino, Elizabeth; Crozeta, Karla; Peres, Aida Maris; Lacerda, Maria Ribeiro

    2017-01-01

    to understand the role of the nurse in the collegiate management model of a teaching hospital, in the integrality of care perspective. a single case study with multiple units of analysis, with the theoretical proposition "integrality of care is a result of the care offered to the user by multiple professionals, including the nurse". Data were obtained in a functional unit of a teaching hospital through interviews with 13 nurses in a non-participant observation and document analysis. from the analytical categories emerged subcategories that allowed understanding that the nurse promotes integrality of care through nursing management, team work and integration of services. the theoretical proposition was confirmed and it was verified that the nursing management focus on attending to health care needs and is a strategy to provide integrality of care. apreender a atuação do enfermeiro no modelo de gestão colegiada de um hospital de ensino na perspectiva do cuidado integral. estudo de caso único de múltiplas unidades de análise, com a proposição teórica "o cuidado integral resulta dos vários cuidados oferecidos ao usuário pelos vários profissionais, dentre esses o enfermeiro". Os dados foram obtidos em uma unidade funcional de um hospital de ensino por meio de entrevistas com 13 enfermeiros, observação não participante e análise de documentos. a partir das categorias analíticas, emergiram subcategorias que possibilitaram apreender que o enfermeiro promove o cuidado integral por meio do gerenciamento de enfermagem, do trabalho em equipe e da integração entre os serviços. ratificou-se a proposição teórica e constatou-se que o gerenciamento de enfermagem volta-se para o atendimento das necessidades de saúde e é uma estratégia para o cuidado integral.

  10. Multiprofissional electronic protocol in ophtalmology with enfasis in strabismus.

    PubMed

    Ribeiro, Christie Graf; Moreira, Ana Tereza Ramos; Pinto, José Simão DE Paula; Malafaia, Osvaldo

    2016-01-01

    "Protocolo Eletrônico" da Oftalmologia ao Sistema Integrado de Protocolos Eletrônicos (SINPE(c)). este é um estudo descritivo e a metodologia aplicada em seu desenvolvimento está didaticamente dividida em três fases: 1) criação da base teórica de dados clínicos de oftalmologia com ênfase em estrabismo; 2) informatização da base teórica dos dados utilizando o SINPE(c); e 3) interpretação das informações com demonstração dos resultados. A informatização da base de dados foi realizada pela utilização da concessão de uso do SINPE(c). Foram incluídos neste protocolo 50 pacientes com estrabismo para validação do protocolo. o protocolo eletrônico desenvolvido permitiu armazenar informações relacionadas à anamnese, exame físico, exames complementares, diagnóstico e tratamento de pacientes com doenças oftalmológicas, com ênfase em estrabismo. Foram incluídos neste trabalho 2141 itens no protocolo mestre e foram criados 20 protocolos específicos de estrabismo, cada um com suas particularidades. Os 50 pacientes que foram incluídos nos protocolos específicos demonstraram a eficácia do método empregado. foi criada uma base eletrônica de dados em oftalmologia com ênfase em estrabismo através da coleta padronizada de informações. Esta base de dados foi informatizada sob a forma de software onde os futuros usuários poderão utilizar o protocolo eletrônico multiprofissional de doenças oftalmológicas com ênfase em estrabismo para a coleta de seus dados.

  11. The Adequacy of the Q Methodology for Clinical Validation of Nursing Diagnoses Related to Subjective Foci.

    PubMed

    Miguel, Susana; Caldeira, Sílvia; Vieira, Margarida

    2016-11-17

    This article describes the adequacy of the Q methodology as a new option for the validation of nursing diagnoses related to subjective foci. Discussion paper about the characteristics of the Q methodology. This method has been used in nursing research particularly related to subjective concepts and includes both a quantitative and qualitative dimension. The Q methodology seems to be an adequate and innovative method for the clinical validation of nursing diagnoses. The validation of nursing diagnoses related to subjective foci using the Q methodology could improve the level of evidence and provide nurses with clinical indicators for clinical reasoning and for the planning of effective interventions. Descrever a adequação da metodologia Q como uma nova opção para a validação clínica de diagnósticos de enfermagem relacionados com focos subjetivos. MÉTODOS: Artigo de discussão sobre as características da metodologia Q. Este método tem sido utilizado na pesquisa em enfermagem relacionada com conceitos subjetivos e inclui em simultâneo uma vertente qualitativa e quantitativa. CONCLUSÕES: A metodologia Q parece ser uma opção metodológica adequada para a validação clínica de diagnósticos de enfermagem. IMPLICAÇÕES PARA A PRÁTICA: A utilização da metodologia Q na validação clínica de diagnósticos de enfermagem relacionados com focos subjetivos pode melhorar o nível e evidência e facilitar o raciocínio clínico dos enfermeiros, ao providenciar indicadores clínicos também necessários ao desenvolvimento de intervenções efetivas. © 2016 NANDA International, Inc.

  12. Projeto observatórios virtuais: educação através de telescópios robóticos

    NASA Astrophysics Data System (ADS)

    Santana, P. H. S.; Shida, R. Y.

    2003-08-01

    O principal objetivo do projeto Observatórios Virtuais é o ensino na área de ciências através de atividades práticas desenvolvidas em colaboração entre instituições de pesquisa em astronomia e escolas de ensino médio e fundamental. Este ano deverá ser concluída a implantação do programa piloto de estudos, pesquisas e observação astronômica direta, com utilização em tempo real de telescópios robóticos, que assim funcionarão como "observatórios virtuais". O objetivo pedagógico das atividades práticas baseadas nas imagens atronômicas é desenvolver as habilidades e competências dos alunos no uso do método científico. Para isso, serão realizados projetos interdisciplinares, a partir de observações astronômicas, já que a astronomia é uma área interdisciplinar por excelência. Essas atividades terão níveis diferenciados de complexidade, que podem ser adequados aos vários graus do ensino e realidades regionais. Será dada ênfase ao desenvolvimento e aplicação em São Paulo, onde atua a equipe do IAG/USP. Como resultados apresentados no presente trabalho, temos a criação de um software em português para o processamento de imagens obtidas através de CCDs e a elaboração de material para as atividades educacionais relacionadas.

  13. Use of technologies in intravenous therapy: contributions to a safer practice.

    PubMed

    Moreira, Ana Paula Amorim; Escudeiro, Cristina Lavoyer; Christovam, Bárbara Pompeu; Silvino, Zenith Rosa; Carvalho, Márglory Fraga de; Silva, Roberto Carlos Lyra da

    2017-01-01

    To identify what are the difficulties of the nursing staff in the management of technologies during intravenous therapy (IVT) and discuss the difficulties identified under the perspective of patient's safety. Descriptive study of qualitative approach with data collected by semi-structured interview and analyzed by the Alceste software. The greatest difficulty of cognitive and technical emphasis was the lack of training; and regarding administrative emphasis, the greatest difficulty was the lack of material and human resources. Infusion pumps and their proper use were highlighted as the technological resource that most contributed to patient safety. The lack of training is presented as the greatest difficulty of nursing professionals and permeates safety issues of both patient and professional when using the hard technologies in IVT. Training is essential to the development of techniques, considered nursing tools. Identificar quais são as dificuldades da equipe de Enfermagem no manejo das tecnologias durante a terapia intravenosa (TIV) e discutir as dificuldades identificadas sob a perspectiva da segurança do paciente. abordagem qualitativa, do tipo descritivo com dados coletados por entrevista semiestruturada e analisados pelo programa Alceste. A maior dificuldade de ênfase cognitiva e técnica foi a falta de treinamento; e de ênfase administrativa, foi a falta de recursos materiais e humanos. As bombas de infusão e sua utilização adequada foram destacadas como o recurso tecnológico que mais contribuiu para a segurança do paciente. A falta de treinamento é apresentada como a maior dificuldade dos profissionais de Enfermagem e permeia as questões de segurança do paciente e do profissional ao utilizar as tecnologias duras na TIV. O treinamento é imprescindível para o desenvolvimento das técnicas, consideradas como ferramentas do fazer da Enfermagem.

  14. Oncology Referral Concerning Paediatric Neurosurgery? Analysis of the Situation between 2008-2013 in the North of Portugal.

    PubMed

    Batista, Ana; Nogueira-Silva, Luís; Vaz, Rui; Oliveira, Joana

    2016-01-01

    Introdução: Os tumores primários do sistema nervoso central representam o segundo grupo de neoplasias mais frequente e são a principal causa de morte devido a tumores sólidos em crianças. O nosso estudo teve como objetivos realizar a mais atualizada análise epidemiológica desta doença no norte de Portugal e avaliar o possível benefício da centralização de cuidados. Material e Métodos: Este estudo de base populacional incluiu todos os tumores primários do sistema nervoso central diagnosticados e histologicamente confirmados em indivíduos menores de 18 anos de idade, que residem no norte do país, desde Janeiro 2008 até Dezembro 2013. Os dados foram obtidos por meio da avaliação dos processos clínicos dos doentes. Nós descrevemos as características das crianças e dos seus tumores e analisámos os quocientes doente: neurocirurgião pediátrico e tipo histológico de tumor: neurocirurgião pediátrico e as taxas de sobrevivência, mortalidade, complicações e recidiva. Resultados: Foram registados 147 casos. A média de idade ao diagnóstico foi de 8,0 ± 5,2 anos. Os astrocitomas foram o tipo histológico mais frequentemente encontrado (34%). O tipo histológico foi a única variável com influência estatisticamente significativa na mortalidade (p = 0,001). As sobrevivências a um, três e cinco anos relativas ao período entre 2008 - 2013 foram estatisticamente superiores às do intervalo entre 2005 - 2007. Os astrocitomas apresentam a mais alta taxa de sobrevivência, sendo estatisticamente diferente dos outros tipos de tumor (p = 0,015). Estimámos uma média de 12,25 casos tratados anualmente por neurocirurgião pediátrico no nosso hospital. Discussão: Os nossos resultados são, globalmente, consistentes com os encontrados na literatura mundial, mas registrámos taxas de sobrevivência mais altas. O número de casos tratados por neurocirurgião pediátrico está de acordo com o recomendado. Conclusão: Demonstrámos que houve melhoria

  15. Indicators of health and safety among institutionalized older adults.

    PubMed

    Cavalcante, Maria Lígia Silva Nunes; Borges, Cíntia Lira; Moura, Acácia Maria Figueiredo Torres de Melo; Carvalho, Rhanna Emanuela Fontenele Lima de

    2016-01-01

    To identify the incidence of mortality, diarrheal diseases, scabies and falls; and the prevalence of pressure ulcers - all of which are related to the safety ofinstitutionalized older adults. This was a documentary retrospective study developed in a long-term residential careinstitution for older adults in the Northeast region of Brazil. The data were gathered from records of health assessment indicators filed between January 2008 and December 2015. Analysis included absolute case frequency; the sum of monthly prevalence and incidence rates; mean values of cases; and mean annual incidence and prevalence rates. The incidence of mortality over these nine years ranged from 9% to 13%; of acute diarrheic disease from 13% to 45%; and scabies from 21% to 63%. The prevalence of pressure ulcers ranged from 8% to 23%. Between 2012 and 2015, the incidence rate of falls without injury varied from 38% to 83%, and with injury from12% to 20%. Analysis of the health indicators revealeda high incidence of scabies and falls and a high prevalence of pressure ulcers. The identification of less than optimal rates for performance indicators canhelp improve the quality of nursing care. Identificar a incidência de mortalidade, doenças diarreicas, escabiose e quedas, e a prevalência de lesões por pressão para a segurança do idoso institucionalizado. Estudo documental, retrospectivo desenvolvido em uma Instituição de Longa Permanência para Idosos, localizada no nordeste do Brasil. Os dados foram coletados por meio dos registros dos indicadores de avaliação de saúde, arquivados de janeiro de 2008 a dezembro de 2015. A análise incluiu a frequência absoluta dos casos; o somatório das taxas de prevalência e incidência mensais; a média de casos e das taxas de incidência e prevalência anuais. Observa-se que a incidência de óbitos nos nove anos considerados variou de 9 a 13%; de doenças diarreicas agudas, de 13 a 45%; e de escabiose, de 21 a 63%. A prevalência de lesão por

  16. [Urinary tract infections in a cohort of kidney transplant recipients].

    PubMed

    Bispo, Ana; Fernandes, Milene; Toscano, Cristina; Marques, Teresa; Machado, Domingos; Weigert, André

    2014-01-01

    Introdução: A infeção do trato urinário é a complicação infeciosa mais comum no período pós transplante renal, estando a sua frequência pouco caracterizada na população portuguesa. Este trabalho teve como objetivo determinar a incidência de infeções do trato urinário e infeções do trato urinário recorrentes em transplantados renais. Material e Métodos: Tratou-se de um estudo observacional de coorte retrospetiva, com consulta dos processos clínicos de doentes transplantados entre Janeiro de 2004 e Dezembro de 2005, no Hospital de Santa Cruz, com seguimento durante cinco anos ou até à data de perda de enxerto, morte ou perda de follow-up. Após uma análise descritiva da população, utilizámos testes bivariados para identificação de fatores associados a infeções do trato urinário. Resultados: Em 127 doentes incluídos com seguimento de 593 doentes/ ano, 53 (41,7%) tiveram pelo menos um episódio de infeção do trato urinário e 21 (16,5%) tiveram infeções do trato urinário recorrentes. O género feminino foi o único fator associado com ocorrência de infeções do trato urinário (p < 0,001, OR = 7,08, RR = 2,95) e infeções do trato urinário recorrentes (p < 0,001, OR = 4,66, RR = 2,83). Os agentes etiológicos mais frequentes foram Escherichia coli (51,6%), Klebsiella pneumoniae (15,5%) e Enterobacter spp (9,9%). As infeções do trato urinário não causaram aumento de mortalidade ou perda de enxerto, mas foram a principal causa de internamentos hospitalares. Discussão: Na nossa população, apenas o género feminino foi identificado como fator de risco para o desenvolvimento de infeções do trato urinário, recorrentes ou não. Escherichia coli foi o agente etiológico mais frequente. Conclusão: Apesar das medidas preventivas adotadas, as infeções do trato urinário continuam a ser uma importante causa de morbilidade e de internamentos hospitalares.

  17. Revista de Saúde Pública: 50 years disseminating the knowledge in nutrition.

    PubMed

    Sichieri, Rosely; Pereira, Rosangela A

    2016-12-22

    This work describes and comments on articles in the area of Public Health Nutrition published in Revista de Saúde Pública (RSP - Public Health Journal) from 1967 to 2016. We searched in the PubMed database restricted to the periodical "Revista de Saúde Pública" and using terms related to key topics in the area of Public Health Nutrition. We retrieved 742 articles and, after exclusion of duplicates and articles unrelated to the subject, we analyzed 441 articles, grouped according to subject: dental caries, anemia, hypovitaminosis A, macro/micronutrients, malnutrition, nutritional assessment, overweight/obesity, food consumption, low birthweight, and breastfeeding. We observed significant increase in the number of articles published and diversification of subjects addressed over the 50 years, representing the consistent development of the scientific field of Nutrition in Brazil. Since its inception, RSP has played an important role in the dissemination of knowledge about the main nutritional issues in Brazil. RESUMO Este trabalho descreve e comenta os artigos na área de Nutrição em Saúde Pública, publicados na Revista de Saúde Pública (RSP) de 1967 a 2016. Foi realizada busca na base de dados PubMed restrita ao periódico "Revista de Saúde Pública" e utilizando termos relacionados com temáticas chaves da área de Nutrição em Saúde Pública. Foram recuperados 742 artigos e, após as exclusões dos artigos repetidos e daqueles não relacionados com a temática, foram analisados 441 artigos, agrupados segundo o tema: cárie dental, anemia, hipovitaminose A, macro/micronutrientes, desnutrição, avaliação do estado nutricional, sobrepeso/obesidade, consumo de alimentos, baixo peso ao nascer, e aleitamento materno. Observou-se incremento significativo no número de artigos publicados e a diversificação dos temas tratados ao longo destes 50 anos, retratando o consistente desenvolvimento do campo científico da Nutrição no Brasil. Desde seu início, a

  18. Health education with older adults: action research with primary care professionals.

    PubMed

    Mendonça, Francielle Toniolo Nicodemos Furtado de; Santos, Álvaro da Silva; Buso, Ana Luisa Zanardo; Malaquias, Bruna Stephanie Sousa

    2017-01-01

    To assess the development and implementation of permanent education action. Quantitative-qualitative research based on action research in three phases (diagnosis of reality, implementation of activity and evaluation), performed with health professionals and managers of basic health units. The evaluation was on the perception of changes immediately following the activity and after 120 days. In the first phase, 110 professionals took part, 36.4% of whom indicated the existence of groups for older adults at work. In the second phase, 98 professionals participated, pointing out interferences of the group in the life of older adults, items of importance and facilitation in forming groups and developing reality-based activities. The third phase showed, in the quantitative analysis, positive impact of the training, and in the qualitative analysis, reassessment of groups, greater knowledge and confidence in managing groups and increased respect for older adults. Permanent education opens pathways for the construction of differentiated care for older adults based on respect and health promotion. Avaliar o desenvolvimento e implementação de uma ação de educação permanente. Pesquisa quantitativo-qualitativa baseada na pesquisa-ação em 3 fases (diagnóstico da realidade, implementação de atividade e avaliação), realizada com profissionais de saúde e gerentes de unidades básicas. A avaliação se deu pela percepção de mudanças imediatamente à atividade e após 120 dias. Na 1ª fase, participaram 110 profissionais, dos quais 36,4% apontaram a existência de grupos para idosos no trabalho. Na 2ª fase, participaram 98 profissionais, que apontaram interferências do grupo na vida do idoso, itens de importância e facilitação para construção de grupos e atividade baseada na realidade. A 3ª fase mostrou, na análise quantitativa, impacto positivo do treinamento; e, na qualitativa, releitura dos grupos e manejo com mais conhecimento, segurança e respeito ao

  19. Healthcare systems, the State, and innovation in the pharmaceutical industry.

    PubMed

    Delgado, Ignacio José Godinho

    2016-11-03

    This article discusses the relations between healthcare systems and the pharmaceutical industry, focusing on state support for pharmaceutical innovation. The study highlights the experiences of the United States, United Kingdom, and Germany, developed countries and paradigms of modern health systems (liberal, universal, and corporatist), in addition to Japan, a case of successful catching up. The study also emphasizes the experiences of China, India, and Brazil, large developing countries that have tried different catching up strategies, with diverse histories and profiles in their healthcare systems and pharmaceutical industries. Finally, with a focus on state forms of support for health research, the article addresses the mechanisms for linkage between health systems and the pharmaceutical industry, evaluating the possibilities of Brazil strengthening a virtuous interaction, favoring the expansion and consolidation of the Brazilian health system - universal but segmented ‒ and the affirmation of the innovative national pharmaceutical industry. Resumo: O artigo discute as relações entre os sistemas de saúde e a indústria farmacêutica, concentrando-se no apoio do Estado à inovação farmacêutica. Salienta as trajetórias dos Estados Unidos, Reino Unido e Alemanha, países desenvolvidos, paradigmáticos dos modernos sistemas de saúde (liberais, universais e corporativos), além do Japão, um caso de emparelhamento bem-sucedido. Também enfatiza as trajetórias de China, Índia e Brasil, países em desenvolvimento, extensos, que experimentaram diferentes estratégias de emparelhamento, dispondo de sistemas de saúde e indústrias farmacêuticas com trajetórias e perfis diversos. Finalmente, com foco nas formas estatais de apoio à pesquisa em saúde, considera os mecanismos de conexão entre os sistemas de saúde e a indústria farmacêutica, avaliando as possibilidades, no Brasil, de fortalecer uma interação virtuosa que favoreça a expansão e

  20. [Psychiatric comorbidities associated with headaches: the experience of the liaison consultation].

    PubMed

    Martins, Vera; Temótio, José; Murta, Ilda

    2015-01-01

    Introdução: A comorbilidade entre cefaleias e perturbações psiquiátricas é frequente, podendo ser explicada quer ao nível de modelos uni ou bidirecionais, quer ao nível da partilha de factores de risco genéticos e ambientais, comuns ao desenvolvimento de ambas as condições clínicas. A presença desta comorbilidade tem implicações importantes, agravando o quadro clínico, aumentando o risco de cronicidade, elevando a intensidade da dor e a taxa de insucesso terapêutico. Material e Métodos: Os autores realizaram um estudo descritivo, retrospectivo, de prevalência, envolvendo 250 doentes observados na consulta de ligação de Psiquiatria-Cefaleias, durante um período de 3 anos, entre 1 de Julho de 2011 e 1 de Julho de 2013, no qual se procedeu à análise dos processos clínicos, relativamente aos dados sociodemográficos e clínicos, diagnóstico psiquiátrico, neurológico e terapêutica prescrita. Resultados e Discussão: Foram efectuadas 689 consultas de ligação Psiquiatria-Cefaleias, verificando-se maior prevalência de doentes do sexo feminino (84%), com média de idades de 47 anos. As cefaleias tipo tensão (60,8%), a enxaqueca (24,8%) e as cefaleias atribuídas a perturbações psiquiátricas (7,2%), foram os tipos mais prevalentes, enquanto as perturbações de humor (62%) e as perturbações neuróticas relacionadas com o stress (39,2%) foram os diagnósticos psiquiátricos mais frequentes na consulta. A intervenção terapêutica nestes casos privilegiou a intervenção multidisciplinar do médico Neurologista e do Psiquiatra, baseando-se na psicoeducação, abordagem cognitivo-comportamental e tratamento psicofarmacológico. Conclusão: Dada a complexidade dos quadros clínicos nos casos de comorbilidade, a experiência da consulta de psiquiatria de ligação e da intervenção multidisciplinar revelou-se uma mais valia no tratamento destes doentes, configurando-se como o cenário mais adequado para o tratamento destas patologias.