Experimental design methodologies in the optimization of chiral CE or CEC separations: an overview.

PubMed

Dejaegher, Bieke; Mangelings, Debby; Vander Heyden, Yvan

2013-01-01

In this chapter, an overview of experimental designs to develop chiral capillary electrophoresis (CE) and capillary electrochromatographic (CEC) methods is presented. Method development is generally divided into technique selection, method optimization, and method validation. In the method optimization part, often two phases can be distinguished, i.e., a screening and an optimization phase. In method validation, the method is evaluated on its fit for purpose. A validation item, also applying experimental designs, is robustness testing. In the screening phase and in robustness testing, screening designs are applied. During the optimization phase, response surface designs are used. The different design types and their application steps are discussed in this chapter and illustrated by examples of chiral CE and CEC methods.

Development and Testing of a M-Learning System for the Professional Development of Academics through Design-Based Action Research

ERIC Educational Resources Information Center

Keskin, Nilgun Ozdamar; Kuzu, Abdullah

2015-01-01

In the present study, a mobile learning system for the professional development of academics was developed by design based action research, and the perceptions and experiences of the academics using this system were examined. In the first phase of this design-based action research, the research question was defined. In the second phase, a…

Alternating phase-shifted mask for logic gate levels, design, and mask manufacturing

NASA Astrophysics Data System (ADS)

Liebmann, Lars W.; Graur, Ioana C.; Leipold, William C.; Oberschmidt, James M.; O'Grady, David S.; Regaill, Denis

1999-07-01

While the benefits of alternating phase shifted masks in improving lithographic process windows at increased resolution are well known throughout the lithography community, broad implementation of this potentially powerful technique has been slow due to the inherent complexity of the layout design and mask manufacturing process. This paper will review a project undertaken at IBM's Semiconductor Research and Development Center and Mask Manufacturing and Development facility to understand the technical and logistical issues associated with the application of alternating phase shifted mask technology to the gate level of a full microprocessor chip. The work presented here depicts an important milestone toward integration of alternating phase shifted masks into the manufacturing process by demonstrating an automated design solution and yielding a functional alternating phase shifted mask. The design conversion of the microprocessor gate level to a conjugate twin shifter alternating phase shift layout was accomplished with IBM's internal design system that automatically scaled the design, added required phase regions, and resolved phase conflicts. The subsequent fabrication of a nearly defect free phase shifted mask, as verified by SEM based die to die inspection, highlights the maturity of the alternating phase shifted mask manufacturing process in IBM's internal mask facility. Well defined and recognized challenges in mask inspection and repair remain and the layout of alternating phase shifted masks present a design and data preparation overhead, but the data presented here demonstrate the feasibility of designing and building manufacturing quality alternating phase shifted masks for the gate level of a microprocessor.

The Outer Planetary Mission Design Project

NASA Astrophysics Data System (ADS)

Benfield, Michael; Turner, M. W.

2010-10-01

With the recent focus from the planetary science community on the outer planets of the solar system, The University of Alabama in Huntsville Integrated Product Team program is embarking on a new challenge to develop an outer planetary mission for the academic year 2010-2011. Currently four bodies are of interest for this mission: Titan, Europa, Triton, and Enceledus, with one body being chosen by the instructors by the beginning of the fall semester. This project will use the 2010 Discovery Announcement of Opportunity as its Request for Proposal (RFP). All of the teams competing in this project will use the AO to respond with a proposal to the instructors for their proposed mission and spacecraft concept. The project employs the two-semester design sequence of the IPT program to provide a framework for the development of this mission. This sequence is divided into four phases. Phase 1 - Requirements Development - focuses on the development of both the scientific and engineering requirements of the mission. During this phase the teams work very closely with the PI organization, represented by the College of Charleston. Phase 2 - Team Formation and Architecture Development - concentrates on the assessment of the overall mission architecture from the launch vehicle to the ground operations of the proposed spacecraft. Phase 3 - System Definition - provides for spacecraft subsystem trade studies and further refinement of the specific spacecraft to meet the scientific requirements and objectives developed in Phase 1. Phase 4 - Design - is the phase where the engineers provide the spacecraft design that is required for the mission of interest. At the conclusion of Phases 2 and 4, an external review board evaluates the proposed designs and chooses one winner of the competition.

Demographic-Based Perceptions of Adequacy of Software Security's Presence within Individual Phases of the Software Development Life Cycle

ERIC Educational Resources Information Center

Kramer, Aleksey

2013-01-01

The topic of software security has become paramount in information technology (IT) related scholarly research. Researchers have addressed numerous software security topics touching on all phases of the Software Development Life Cycle (SDLC): requirements gathering phase, design phase, development phase, testing phase, and maintenance phase.…

Analysis of remote operating systems for space-based servicing operations, volume 1

NASA Technical Reports Server (NTRS)

1985-01-01

A two phase study was conducted to analyze and develop the requirements for remote operating systems as applied to space based operations for the servicing, maintenance, and repair of satellites. Phase one consisted of the development of servicing requirements to establish design criteria for remote operating systems. Phase two defined preferred system concepts and development plans which met the requirements established in phase one. The specific tasks in phase two were to: (1) identify desirable operational and conceptual approaches for selected mission scenarios; (2) examine the potential impact of remote operating systems incorporated into the design of the space station; (3) address remote operating systems design issues, such as mobility, which are effected by the space station configuration; and (4) define the programmatic approaches for technology development, testing, simulation, and flight demonstration.

Phase 2 design study of the electronic assembly for the HRUV spectrometer/polarimeter intended for the solar maximum mission. Implementation phase program plan, revision A

NASA Technical Reports Server (NTRS)

1977-01-01

The primary function of the implementation phase is to convert the ERA design of the design study phase into deliverable flight hardware. The development aspects of the experiment logic unit, the dual power converter, the junction box and the cables are considered.

Design specifications for NALDA (Naval Aviation Logistics Data Analysis) CAI (computer aided instruction): Phase 2, Interim report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Twitty, A.F.; Handler, B.H.; Duncan, L.D.

Data Systems Engineering Organization (DSEO) personnel are developing a prototype computer aided instruction (CAI) system for the Naval Aviation Logistics Data Analysis (NALDA) system. The objective of this project is to provide a prototype for implementing CAI as an enhancement to existing NALDA training. The CAI prototype project is being performed in phases. The task undertaken in Phase I was to analyze the problem and the alternative solutions and to develop a set of recommendations on how best to proceed. In Phase II a structured design and specification document was completed that will provide the basis for development and implementationmore » of the desired CAI system. Phase III will consist of designing, developing, and testing a user interface which will extend the features of the Phase II prototype. The design of the CAI prototype has followed a rigorous structured analysis based on Yourdon/DeMarco methodology and Information Engineering tools. This document includes data flow diagrams, a data dictionary, process specifications, an entity-relationship diagram, a curriculum description, special function key definitions, and a set of standards developed for the NALDA CAI Prototype.« less

Evaluation of HiPHES convective reformer design alternatives. Phase 2, Final issue

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1991-08-01

Phase I Stone & Webster presented three potential design configurations for a ceramic-tubed steam-methane reformer. These were the Tube-Within-a-Tube (TWIT) design, the Once-Through design, and the Monolith design. Although the TWIT design configuration appeared to be the most viable, the inclusion of a more detailed examination of design alternatives for the HiPHES reformer was deemed appropriate for the Phase II program. Of particular concern was the length of the ceramic tubes required for the TWIT design. To assist in this evaluation, Stone & Webster established a Development Team consisting of specialists in the areas of heat transfer, ceramic materials, exchangermore » design, vessel design, and potential users. Stone & Webster reviewed the critical areas of concern for a ceramic convective reformer, evaluated competing design configurations, and presented the results to the Development Team. This report presents Stone & Webster`s evaluations and the comments and recommendations of the Development Team. This effort comprised the majority of Task 1 of Phase II of Stone & Webster`s HiPHES project. The design review was executed in parallel with the material coupon screening tests at BP America. The goal of both tasks was to confirm the materials selection and reformer design configuration so that the conditions for the tube and joint tests to be conducted at Oak Ridge National Laboratory (ORNL) could be specified. The ORNL tests are intended to evaluate the reformer design configuration and materials of construction used for the reformer design in Phase II, and to be used in the demonstration unit in Phase III. The Task 1 (Evaluation of Alternative Reformer Designs) effort has identified a preferred design configuration for the proposed ceramic reformer. Additional engineering and material evaluation work is necessary before an operating prototype can be designed.« less

Space station experiment definition: Long-term cryogenic fluid storage

NASA Technical Reports Server (NTRS)

Jetley, R. L.; Scarlotti, R. D.

1987-01-01

The conceptual design of a space station Technology Development Mission (TDM) experiment to demonstrate and evaluate cryogenic fluid storage and transfer technologies is presented. The experiment will be deployed on the initial operational capability (IOC) space station for a four-year duration. It is modular in design, consisting of three phases to test the following technologies: passive thermal technologies (phase 1), fluid transfer (phase 2), and active refrigeration (phase 3). Use of existing hardware was a primary consideration throughout the design effort. A conceptual design of the experiment was completed, including configuration sketches, system schematics, equipment specifications, and space station resources and interface requirements. These requirements were entered into the NASA Space Station Mission Data Base. A program plan was developed defining a twelve-year development and flight plan. Program cost estimates are given.

Designing for Learner Success (D4LS) at Otago Polytechnic: From an E-learning Designer's Perspective

ERIC Educational Resources Information Center

Gedera, Dilani S. P.

2016-01-01

Otago Polytechnic (OP) is currently redesigning and redeveloping its programmes and courses under an institution-wide initiative called Designing for Learner Success (D4LS). This initiative has several phases--design, development, delivery, and evaluation. This article focuses on the processes and considerations in the development phase of D4LS,…

Development of a 300 Amp-hr high rate lithium thionyl chloride cell

NASA Technical Reports Server (NTRS)

Boyle, Gerard H.

1991-01-01

The development of a high-rate lithium thionyl chloride cylindrical cell with parallel plate electrodes is discussed. The development was divided into three phases: phase 1, a 150 Amp/hour low rate (1 mA/sq cm) design; phase 2, a 25 Amp/hour high rate (5 mA/sq cm) design; and phase 3, a 300 Amp/hour high rate (5 mA/sq cm) design. The basic design is the same for all three cells. The electrodes are perpendicular to the axis of the cylinder. Multiple electrodes are bussed up the side of the cylinder, 180 deg apart allowing excellent anode and cathode utilization. It is a lithium limited design with excess electrolyte. The cathode is Shawinigan or Gulf Acetylene black with no catalyst. The electrolyte is 1.8 Molar lithium tetrachloroaluminate (LiAlCl4) in thionyl chloride. All cell cases are 304L Stainless Steel with a BS&B burst disc.

Reliability and the design process at Honeywell Avionics Division

NASA Technical Reports Server (NTRS)

Bezat, A.

1981-01-01

The division's philosophy for designed-in reliability and a comparison of reliability programs for space, manned military aircraft, and commercial aircraft, are presented. Topics include: the reliability interface with design and production; the concept phase through final proposal; the design, development, test and evaluation phase; the production phase; and the commonality among space, military, and commercial avionics.

Designing Computer-Based Assessments: Multidisciplinary Findings and Student Perspectives

ERIC Educational Resources Information Center

Dembitzer, Leah; Zelikovitz, Sarah; Kettler, Ryan J.

2017-01-01

A partnership was created between psychologists and computer programmers to develop a computer-based assessment program. Psychometric concerns of accessibility, reliability, and validity were juxtaposed with core development concepts of usability and user-centric design. Phases of development were iterative, with evaluation phases alternating with…

Apollo CSM Power Generation System Design Considerations, Failure Modes and Lessons Learned

NASA Technical Reports Server (NTRS)

Interbartolo, Michael

2009-01-01

The objectives of this slide presentation are to: review the basic design criteria for fuel cells (FC's), review design considerations during developmental phase that affected Block I and Block II vehicles, summarize the conditions that led to the failure of components in the FC's, and state the solution implemented for each failure. It reviews the location of the fuel cells, the fuel cell theory the design criteria going into development phase and coming from the development phase, failures and solutions of Block I and II, and the lessons learned.

The Development of Attention and Response Inhibition in Early Childhood

ERIC Educational Resources Information Center

Bartgis, Jami; Thomas, David G.; Lefler, Elizabeth K.; Hartung, Cynthia M.

2008-01-01

The goal of this study was to examine the development of attention and response inhibition from ages 5 to 7. Forty children (20 5-year-olds and 20 7-year-olds) completed four counterbalanced phases of a continuous performance task. Phase 1 was designed to measure attention without distraction, Phase 2 was designed to measure attention with…

EARLY ENTRANCE COPRODUCTION PLANT

DOE Office of Scientific and Technical Information (OSTI.GOV)

David Storm; Govanon Nongbri; Steve Decanio

2004-01-12

The overall objective of this project is the three phase development of an Early Entrance Coproduction Plant (EECP) which uses petroleum coke to produce at least one product from at least two of the following three categories: (1) electric power (or heat), (2) fuels, and (3) chemicals using ChevronTexaco's proprietary gasification technology. The objective of Phase I is to determine the feasibility and define the concept for the EECP located at a specific site; develop a Research, Development, and Testing (RD&T) Plan to mitigate technical risks and barriers; and prepare a Preliminary Project Financing Plan. The objective of Phase IImore » is to implement the work as outlined in the Phase I RD&T Plan to enhance the development and commercial acceptance of coproduction technology. The objective of Phase III is to develop an engineering design package and a financing and testing plan for an EECP located at a specific site. The project's intended result is to provide the necessary technical, economic, and environmental information needed by industry to move the EECP forward to detailed design, construction, and operation. The partners in this project are Texaco Energy Systems LLC or TES (a subsidiary of ChevronTexaco), General Electric (GE), Praxair, and Kellogg Brown & Root (KBR) in addition to the U.S. Department of Energy (DOE). TES is providing gasification technology and Fischer-Tropsch (F-T) technology developed by Rentech, Inc., GE is providing combustion turbine technology, Praxair is providing air separation technology, and KBR is providing engineering. During Phase I, a design basis for the Fischer-Tropsch Synthesis section was developed based on limited experience with the specified feed gas and operating conditions. The objective of this Task in Phase II RD&T work was to confirm the performance of the F-T reactor at the set design conditions. Although much of the research, development, and testing work were done by TES outside of this project, several important issues were addressed in this phase of the project. They included Rejuvenation/Regeneration of the Fischer-Tropsch Catalyst, online Catalyst Withdrawal and Addition from the synthesis reactor, and the Fischer-Tropsch Design Basis Confirmation. In Phase III the results from these RD&T work will be incorporated in developing the engineering design package. This Topical Report documents the Phase II RD&T work that was completed for this task.« less

S-band antenna phased array communications system

NASA Technical Reports Server (NTRS)

Delzer, D. R.; Chapman, J. E.; Griffin, R. A.

1975-01-01

The development of an S-band antenna phased array for spacecraft to spacecraft communication is discussed. The system requirements, antenna array subsystem design, and hardware implementation are examined. It is stated that the phased array approach offers the greatest simplicity and lowest cost. The objectives of the development contract are defined as: (1) design of a medium gain active phased array S-band communications antenna, (2) development and test of a model of a seven element planar array of radiating elements mounted in the appropriate cavity matrix, and (3) development and test of a breadboard transmit/receive microelectronics module.

Pharmacogenomics in early-phase clinical development

PubMed Central

Burt, Tal; Dhillon, Savita

2015-01-01

Pharmacogenomics (PGx) offers the promise of utilizing genetic fingerprints to predict individual responses to drugs in terms of safety, efficacy and pharmacokinetics. Early-phase clinical trial PGx applications can identify human genome variations that are meaningful to study design, selection of participants, allocation of resources and clinical research ethics. Results can inform later-phase study design and pipeline developmental decisions. Nevertheless, our review of the clinicaltrials.gov database demonstrates that PGx is rarely used by drug developers. Of the total 323 trials that included PGx as an outcome, 80% have been conducted by academic institutions after initial regulatory approval. Barriers for the application of PGx are discussed. We propose a framework for the role of PGx in early-phase drug development and recommend PGx be universally considered in study design, result interpretation and hypothesis generation for later-phase studies, but PGx results from underpowered studies should not be used by themselves to terminate drug-development programs. PMID:23837482

Designing for Change: Minimizing the Impact of Changing Requirements in the Later Stages of a Spaceflight Software Project

NASA Technical Reports Server (NTRS)

Allen, B. Danette

1998-01-01

In the traditional 'waterfall' model of the software project life cycle, the Requirements Phase ends and flows into the Design Phase, which ends and flows into the Development Phase. Unfortunately, the process rarely, if ever, works so smoothly in practice. Instead, software developers often receive new requirements, or modifications to the original requirements, well after the earlier project phases have been completed. In particular, projects with shorter than ideal schedules are highly susceptible to frequent requirements changes, as the software requirements analysis phase is often forced to begin before the overall system requirements and top-level design are complete. This results in later modifications to the software requirements, even though the software design and development phases may be complete. Requirements changes received in the later stages of a software project inevitably lead to modification of existing developed software. Presented here is a series of software design techniques that can greatly reduce the impact of last-minute requirements changes. These techniques were successfully used to add built-in flexibility to two complex software systems in which the requirements were expected to (and did) change frequently. These large, real-time systems were developed at NASA Langley Research Center (LaRC) to test and control the Lidar In-Space Technology Experiment (LITE) instrument which flew aboard the space shuttle Discovery as the primary payload on the STS-64 mission.

Development of wave and surge atlas for the design and protection of coastal bridges in South Louisiana - phase 2.

DOT National Transportation Integrated Search

2016-09-01

This report summarizes the work performed by INTERA Incorporated (INTERA), for the Louisiana Department of Transportation and Development (DOTD) on Phase 2 of LTRC project No. 10-4ST, Development of Wave and Surge Atlas for the Design Protection o...

A design concept for an MMIC (Monolithic Microwave Integrated Circuit) microstrip phased array

NASA Technical Reports Server (NTRS)

Lee, Richard Q.; Smetana, Jerry; Acosta, Roberto

1987-01-01

A conceptual design for a microstrip phased array with monolithic microwave integrated circuit (MMIC) amplitude and phase controls is described. The MMIC devices used are 20 GHz variable power amplifiers and variable phase shifters recently developed by NASA contractors for applications in future Ka proposed design, which concept is for a general NxN element array of rectangular lattice geometry. Subarray excitation is incorporated in the MMIC phased array design to reduce the complexity of the beam forming network and the number of MMIC components required.

AN INNOVATIVE DESIGN FOR ANAEROBIC CO-DIGESTION OF ANIMAL WASTES FOR SUSTAINABLE DEVELOPMENT IN RURAL COMMUNITIES

EPA Science Inventory

With the aim of the Phase I project to develop an innovative anaerobic co-digestion design for the treatment of dairy manure and poultry waste, our Phase I team has evaluated the technical and economic feasibility of the anaerobic co-digestion design concept with a thorough in...

Installation Restoration Program. Phase II--Confirmation/Quantification. Stage 1.

DTIC Science & Technology

1985-03-01

four phases. Phase I, Initial Assessment/ Records Search, is designed to identify possible hazardous waste contami- nated sites and potential...7 71 -. - - IL’ -, 1% 33 AihlIII Is 33 n~iL t iiC UII! ii CL C LU 1-3, Phase II, Confirmation and Quantification, is designed to confirm the...additional monitoring data upon which design of mitigative actions are based. In Phase III, Technology Base Development, appropriate technology is selected and

Army-NASA aircrew/aircraft integration program (A3I) software detailed design document, phase 3

NASA Technical Reports Server (NTRS)

Banda, Carolyn; Chiu, Alex; Helms, Gretchen; Hsieh, Tehming; Lui, Andrew; Murray, Jerry; Shankar, Renuka

1990-01-01

The capabilities and design approach of the MIDAS (Man-machine Integration Design and Analysis System) computer-aided engineering (CAE) workstation under development by the Army-NASA Aircrew/Aircraft Integration Program is detailed. This workstation uses graphic, symbolic, and numeric prototyping tools and human performance models as part of an integrated design/analysis environment for crewstation human engineering. Developed incrementally, the requirements and design for Phase 3 (Dec. 1987 to Jun. 1989) are described. Software tools/models developed or significantly modified during this phase included: an interactive 3-D graphic cockpit design editor; multiple-perspective graphic views to observe simulation scenarios; symbolic methods to model the mission decomposition, equipment functions, pilot tasking and loading, as well as control the simulation; a 3-D dynamic anthropometric model; an intermachine communications package; and a training assessment component. These components were successfully used during Phase 3 to demonstrate the complex interactions and human engineering findings involved with a proposed cockpit communications design change in a simulated AH-64A Apache helicopter/mission that maps to empirical data from a similar study and AH-1 Cobra flight test.

Extension of quality-by-design concept to the early development phase of pharmaceutical R&D processes.

PubMed

Csóka, Ildikó; Pallagi, Edina; Paál, Tamás L

2018-03-27

Here, we propose the extension of the quality-by-design (QbD) concept to also fit the early development phases of pharmaceuticals by adding elements that are currently widely applied, but not yet included in the QbD model in a structured way. These are the introduction of a 'zero' preformulation phase (i.e., selection of drug substance, possible dosage forms and administration routes based on the evaluated therapeutic need); building in stakeholders' (industry, patient, and regulatory) requirements into the quality target product profile (QTTP); and the use of modern quality management tools during the composition and process design phase [collecting critical quality attributes (CQAs) and selection of CPPs) for (still laboratory-scale) design space (DS) development. Moreover, during industrial scale-up, CQAs (as well as critical process parameters; CPPs) can be changed; however, we recommend that the existing QbD elements are reconsidered and updated after this phase. Copyright © 2018 Elsevier Ltd. All rights reserved.

Conceptual design study for a teleoperator visual system, phase 1

NASA Technical Reports Server (NTRS)

Adams, D.; Grant, C.; Johnson, C.; Meirick, R.; Polhemus, C.; Ray, A.; Rittenhouse, D.; Skidmore, R.

1972-01-01

Results are reported for work performed during the first phase of the conceptual design study for a teleoperator visual system. This phase consists of four tasks: General requirements, concept development, subsystem requirements and analysis, and concept evaluation.

High Temperature Metallic Seal Development For Aero Propulsion and Gas Turbine Applications

NASA Technical Reports Server (NTRS)

More, Greg; Datta, Amit

2006-01-01

A viewgraph presentation on metallic high temperature static seal development at NASA for gas turbine applications is shown. The topics include: 1) High Temperature Static Seal Development; 2) Program Review; 3) Phase IV Innovative Seal with Blade Alloy Spring; 4) Spring Design; 5) Phase IV: Innovative Seal with Blade Alloy Spring; 6) PHase IV: Testing Results; 7) Seal Seating Load; 8) Spring Seal Manufacturing; and 9) Other Applications for HIgh Temperature Spring Design

Impact of Availability of Companion Diagnostics on the Clinical Development of Anticancer Drugs.

PubMed

Tibau, Ariadna; Díez-González, Laura; Navarro, Beatriz; Galán-Moya, Eva M; Templeton, Arnoud J; Seruga, Bostjan; Pandiella, Atanasio; Amir, Eitan; Ocana, Alberto

2017-06-01

Companion diagnostics permit the selection of patients likely to respond to targeted anticancer drugs; however, it is unclear if the drug development process differs between drugs developed with or without companion diagnostics. Identification of differences in study design could help future clinical development. Anticancer drugs approved for use in solid tumors between 28 September 2000 and 4 January 2014 were identified using a search of the US FDA website. Phase III trials supporting registration were extracted from the drug label. Each published study was reviewed to obtain information about the phase I and II trials used for the development of the respective drug. We identified 35 drugs and 59 phase III randomized trials supporting regulatory approval. Fifty-three phase I trials and 47 phase II trials were cited in the studies and were used to support the design of these phase III trials. The approval of drugs using a companion diagnostic has increased over time (p for trend 0.01). Expansion cohorts were more frequently observed with drugs developed with a companion diagnostic (62 vs. 20%; p = 0.005). No differences between drugs developed with or without a companion diagnostic were observed for the design of phase I and II studies. The approval of drugs developed with a companion diagnostic has increased over time. The availability of a companion diagnostic was associated with more frequent use of phase I expansion cohorts comprising patients selected by the companion diagnostic.

The Department of Defense Small Business Technology Transfer (STTR) FY 2000

DTIC Science & Technology

2000-01-04

applications (e.g. drug design, pharmacogenomics, and modeling of cells and organs). DARPA - 6 PHASE I: Develop a high performance database...Army, and particularly the Dismounted Soldier, has need for high -energy, lightweight power sources. Polymer electrolyte membrane fuel cells (PEM FCs... efficiently processed fabricated, and tailored to resist high velocity impact and penetration should be developed. PHASE II: Prototype designs from Phase I

Development of Environmental Load Estimation Model for Road Drainage Systems in the Early Design Phase

NASA Astrophysics Data System (ADS)

Park, Jin-Young; Lee, Dong-Eun; Kim, Byung-Soo

2017-10-01

Due to the increasing concern about climate change, efforts to reduce environmental load are continuously being made in construction industry, and LCA (life cycle assessment) is being presented as an effective method to assess environmental load. Since LCA requires information on construction quantity used for environmental load estimation, however, it is not being utilized in the environmental review in the early design phase where it is difficult to obtain such information. In this study, computation system for construction quantity based on standard cross section of road drainage facilities was developed to compute construction quantity required for LCA using only information available in the early design phase to develop and verify the effectiveness of a model that can perform environmental load estimation. The result showed that it is an effective model that can be used in the early design phase as it revealed a 13.39% mean absolute error rate.

Advanced launch system. Advanced development oxidizer turbopump program

NASA Technical Reports Server (NTRS)

1993-01-01

On May 19, 1989, Pratt & Whitney was awarded contract NAS8-37595 by the National Aeronautics and Space Administration, Marshall Space Flight Center, Huntsville Alabama for an Advanced Development Program (ADP) to design, develop and demonstrate a highly reliable low cost, liquid oxygen turbopump for the Advanced Launch System (ALS). The ALS had an overall goal of reducing the cost of placing payloads in orbit by an order of magnitude. This goal would require a substantial reduction in life cycle costs, with emphasis on recurring costs, compared to current launch vehicles. Engine studies supporting these efforts were made for the Space Transportation Main Engine (STME). The emphasis on low cost required design simplification of components and subsystems such that the ground maintenance and test operations was minimized. The results of the Oxygen Turbopump ADP technology effort would provide data to be used in the STME. Initially the STME baseline was a gas generator cycle engine with a vacuum thrust level of 580,000 lbf. This was later increased to 650,000 lbf and the oxygen turbopump design approach was changed to reflect the new thrust level. It was intended that this ADP program be conducted in two phases. Phase 1, a basic phase, would encompass the preliminary design effort, and Phase II, an optional contract phase to cover design, fabrication and test evaluation of an oxygen turbopump at a component test facility at the NASA John C. Stennis Space Center in Mississippi. The basic phase included preliminary design and analysis, evaluation of low cost concepts, and evaluation of fabrication techniques. The option phase included design of the pump and support hardware, analysis of the final configuration to ensure design integrity, fabrication of hardware to demonstrate low cost, DVS Testing of hardware to verify the design, assembly of the turbopump and full scale turbopump testing. In December 1990, the intent of this ADP to support the design and development was changed. The design effort for the oxygen turbopump became part of the STME Phase B contract. The status of the pump design funded through this ADP was presented at the Preliminary Design Review (PDR) at the MSFC on October 24, 1990. Advancements in the design of the pump were subsequently continued under the Phase B Contract. The emphasis of this ADP became the demonstration of individual technologies that would have the greatest potential for reducing the recurring cost and increasing reliability. In October of 1992, overall program funding was reduced and work on this ADP was terminated.

Advanced launch system. Advanced development oxidizer turbopump program

NASA Astrophysics Data System (ADS)

1993-10-01

On May 19, 1989, Pratt & Whitney was awarded contract NAS8-37595 by the National Aeronautics and Space Administration, Marshall Space Flight Center, Huntsville Alabama for an Advanced Development Program (ADP) to design, develop and demonstrate a highly reliable low cost, liquid oxygen turbopump for the Advanced Launch System (ALS). The ALS had an overall goal of reducing the cost of placing payloads in orbit by an order of magnitude. This goal would require a substantial reduction in life cycle costs, with emphasis on recurring costs, compared to current launch vehicles. Engine studies supporting these efforts were made for the Space Transportation Main Engine (STME). The emphasis on low cost required design simplification of components and subsystems such that the ground maintenance and test operations was minimized. The results of the Oxygen Turbopump ADP technology effort would provide data to be used in the STME. Initially the STME baseline was a gas generator cycle engine with a vacuum thrust level of 580,000 lbf. This was later increased to 650,000 lbf and the oxygen turbopump design approach was changed to reflect the new thrust level. It was intended that this ADP program be conducted in two phases. Phase 1, a basic phase, would encompass the preliminary design effort, and Phase II, an optional contract phase to cover design, fabrication and test evaluation of an oxygen turbopump at a component test facility at the NASA John C. Stennis Space Center in Mississippi. The basic phase included preliminary design and analysis, evaluation of low cost concepts, and evaluation of fabrication techniques. The option phase included design of the pump and support hardware, analysis of the final configuration to ensure design integrity, fabrication of hardware to demonstrate low cost, DVS Testing of hardware to verify the design, assembly of the turbopump and full scale turbopump testing. In December 1990, the intent of this ADP to support the design and development was changed. The design effort for the oxygen turbopump became part of the STME Phase B contract. The status of the pump design funded through this ADP was presented at the Preliminary Design Review (PDR) at the MSFC on October 24, 1990. Advancements in the design of the pump were subsequently continued under the Phase B Contract. The emphasis of this ADP became the demonstration of individual technologies that would have the greatest potential for reducing the recurring cost and increasing reliability. In October of 1992, overall program funding was reduced and work on this ADP was terminated.

Cassini/Titan-4 Acoustic Blanket Development and Testing

NASA Technical Reports Server (NTRS)

Hughes, William O.; McNelis, Anne M.

1996-01-01

NASA Lewis Research Center recently led a multi-organizational effort to develop and test verify new acoustic blankets. These blankets support NASA's goal in reducing the Titan-4 payload fairing internal acoustic environment to allowable levels for the Cassini spacecraft. To accomplish this goal a two phase acoustic test program was utilized. Phase One consisted of testing numerous blanket designs in a flat panel configuration. Phase Two consisted of testing the most promising designs out of Phase One in a full scale cylindrical payload fairing. This paper will summarize this highly successful test program by providing the rationale and results for each test phase, the impacts of this testing on the Cassini mission, as well as providing some general information on blanket designs.

Space transfer vehicle concepts and requirements study, phase 2

NASA Technical Reports Server (NTRS)

Cannon, Jeffrey H.; Vinopal, Tim; Andrews, Dana; Richards, Bill; Weber, Gary; Paddock, Greg; Maricich, Peter; Bouton, Bruce; Hagen, Jim; Kolesar, Richard

1992-01-01

This final report is a compilation of the Phase 1 and Phase 2 study findings and is intended as a Space Transfer Vehicle (STV) 'users guide' rather than an exhaustive explanation of STV design details. It provides a database for design choices in the general areas of basing, reusability, propulsion, and staging; with selection criteria based on cost, performance, available infrastructure, risk, and technology. The report is organized into the following three parts: (1) design guide; (2) STV Phase 1 Concepts and Requirements Study Summary; and (3) STV Phase 2 Concepts and Requirements Study Summary. The overall objectives of the STV study were to: (1) define preferred STV concepts capable of accommodating future exploration missions in a cost-effective manner; (2) determine the level of technology development required to perform these missions in the most cost effective manner; and (3) develop a decision database of programmatic approaches for the development of an STV concept.

Development history of the Hybrid Test Vehicle

NASA Technical Reports Server (NTRS)

Trummel, M. C.; Burke, A. F.

1983-01-01

Phase I of a joint Department of Energy/Jet Propulsion Laboratory Program undertook the development of the Hybrid Test Vehicle (HTV), which has subsequently progressed through design, fabrication, and testing and evaluation phases. Attention is presently given to the design and test experience gained during the HTV development program, and a discussion is presented of the design features and performance capabilities of the various 'mule' vehicles, devoted to the separate development of engine microprocessor control, vehicle structure, and mechanical components, whose elements were incorporated into the final HTV design. Computer projections of the HTV's performance are given.

Orbital express capture system: concept to reality

NASA Astrophysics Data System (ADS)

Stamm, Shane; Motaghedi, Pejmun

2004-08-01

The development of autonomous servicing of on-orbit spacecraft has been a sought after objective for many years. A critical component of on-orbit servicing involves the ability to successfully capture, institute mate, and perform electrical and fluid transfers autonomously. As part of a Small Business Innovation Research (SBIR) grant, Starsys Research Corporation (SRC) began developing such a system. Phase I of the grant started in 1999, with initial work focusing on simultaneously defining the parameters associated with successful docking while designing to those parameters. Despite the challenge of working without specific requirements, SRC completed development of a prototype design in 2000. Throughout the following year, testing was conducted on the prototype to characterize its performance. Having successfully completed work on the prototype, SRC began a Phase II SBIR effort in mid-2001. The focus of the second phase was a commercialization effort designed to augment the prototype model into a more flight-like design. The technical requirements, however, still needed clear definition for the design to progress. The advent of the Orbital Express (OE) program provided much of that definition. While still in the proposal stages of the OE program, SRC began tailoring prototype redesign efforts to the OE program requirements. A primary challenge involved striking a balance between addressing the technical requirements of OE while designing within the scope of the SBIR. Upon award of the OE contract, the Phase II SBIR design has been fully developed. This new design, designated the Mechanical Docking System (MDS), successfully incorporated many of the requirements of the OE program. SRC is now completing dynamic testing on the MDS hardware, with a parallel effort of developing a flight design for OE. As testing on the MDS progresses, the design path that was once common to both SBIR effort and the OE program begins to diverge. The MDS will complete the scope of the Phase II SBIR work, while the new mechanism, the Orbital Express Capture System, will emerge as a flight-qualified design for the Orbital Express program.

Amorphous silicon photovoltaic manufacturing technology, phase 2A

NASA Astrophysics Data System (ADS)

Duran, G.; Mackamul, K.; Metcalf, D.

1995-01-01

Utility Power Group (UPG), and its lower-tier subcontractor, Advanced Photovoltaic Systems, Inc. (APS) have conducted efforts in developing their manufacturing lines. UPG has focused on the automation of encapsulation and termination processes developed in Phase 1. APS has focused on completion of the encapsulation and module design tasks, while continuing the process and quality control and automation projects. The goal is to produce 55 watt (stabilized) EP50 modules in a new facility. In the APS Trenton EUREKA manufacturing facility, APS has: (1) Developed high throughput lamination procedures; (2) Optimized existing module designs; (3) Developed new module designs for architectural applications; (4) Developed enhanced deposition parameter control; (5) Designed equipment required to manufacture new EUREKA modules developed during Phase II; (6) Improved uniformity of thin-film materials deposition; and (7) Improved the stabilized power output of the APS EP50 EUREKA module to 55 watts. In the APS Fairfield EUREKA manufacturing facility, APS has: (1) Introduced the new products developed under Phase 1 into the APS Fairfield EUREKA module production line; (2) Increased the extent of automation in the production line; (3) Introduced Statistical Process Control to the module production line; and (4) Transferred-progress made in the APS Trenton facility into the APS Fairfield facility.

Validity of High School Physic Module With Character Values Using Process Skill Approach In STKIP PGRI West Sumatera

NASA Astrophysics Data System (ADS)

Anaperta, M.; Helendra, H.; Zulva, R.

2018-04-01

This study aims to describe the validity of physics module with Character Oriented Values Using Process Approach Skills at Dynamic Electrical Material in high school physics / MA and SMK. The type of research is development research. The module development model uses the development model proposed by Plomp which consists of (1) preliminary research phase, (2) the prototyping phase, and (3) assessment phase. In this research is done is initial investigation phase and designing. Data collecting technique to know validation is observation and questionnaire. In the initial investigative phase, curriculum analysis, student analysis, and concept analysis were conducted. In the design phase and the realization of module design for SMA / MA and SMK subjects in dynamic electrical materials. After that, the formative evaluation which include self evaluation, prototyping (expert reviews, one-to-one, and small group. At this stage validity is performed. This research data is obtained through the module validation sheet, which then generates a valid module.

Safety Guided Design of Crew Return Vehicle in Concept Design Phase Using STAMP/STPA

NASA Astrophysics Data System (ADS)

Nakao, H.; Katahira, M.; Miyamoto, Y.; Leveson, N.

2012-01-01

In the concept development and design phase of a new space system, such as a Crew Vehicle, designers tend to focus on how to implement new technology. Designers also consider the difficulty of using the new technology and trade off several system design candidates. Then they choose an optimal design from the candidates. Safety should be a key aspect driving optimal concept design. However, in past concept design activities, safety analysis such as FTA has not used to drive the design because such analysis techniques focus on component failure and component failure cannot be considered in the concept design phase. The solution to these problems is to apply a new hazard analysis technique, called STAMP/STPA. STAMP/STPA defines safety as a control problem rather than a failure problem and identifies hazardous scenarios and their causes. Defining control flow is the essential in concept design phase. Therefore STAMP/STPA could be a useful tool to assess the safety of system candidates and to be part of the rationale for choosing a design as the baseline of the system. In this paper, we explain our case study of safety guided concept design using STPA, the new hazard analysis technique, and model-based specification technique on Crew Return Vehicle design and evaluate benefits of using STAMP/STPA in concept development phase.

A four phase development model for integrated care services in the Netherlands

PubMed Central

Minkman, Mirella MN; Ahaus, Kees TB; Huijsman, Robbert

2009-01-01

Background Multidisciplinary and interorganizational arrangements for the delivery of coherent integrated care are being developed in a large number of countries. Although there are many integrated care programs worldwide, the process of developing these programs and interorganizational collaboration is described in the literature only to a limited extent. The purpose of this study is to explore how local integrated care services are developed in the Netherlands, and to conceptualize and operationalize a development model of integrated care. Methods The research is based on an expert panel study followed by a two-part questionnaire, designed to identify the development process of integrated care. Essential elements of integrated care, which were developed in a previous Delphi and Concept Mapping Study, were analyzed in relation to development process of integrated care. Results Integrated care development can be characterized by four developmental phases: the initiative and design phase; the experimental and execution phase; the expansion and monitoring phase; and the consolidation and transformation phase. Different elements of integrated care have been identified in the various developmental phases. Conclusion The findings provide a descriptive model of the development process that integrated care services can undergo in the Netherlands. The findings have important implications for integrated care services, which can use the model as an instrument to reflect on their current practices. The model can be used to help to identify improvement areas in practice. The model provides a framework for developing evaluation designs for integrated care arrangements. Further research is recommended to test the developed model in practice and to add international experiences. PMID:19261176

Personnel launch system autoland development study

NASA Technical Reports Server (NTRS)

Bossi, J. A.; Langehough, M. A.; Tollefson, J. C.

1991-01-01

The Personnel Launch System (PLS) Autoland Development Study focused on development of the guidance and control system for the approach and landing (A/L) phase and the terminal area energy management (TAEM) phase. In the A/L phase, a straight-in trajectory profile was developed with an initial high glide slope, a pull-up and flare to lower glide slope, and the final flare touchdown. The TAEM system consisted of using a heading alignment cone spiral profile. The PLS autopilot was developed using integral LQG design techniques. The guidance and control design was verified using a nonlinear 6 DOF simulation. Simulation results demonstrated accurate steering during the TAEM phase and adequate autoland performance in the presence of wind turbulence and wind shear.

Design Considerations for Fusible Heat Sink

NASA Technical Reports Server (NTRS)

Cognata, Thomas J.; Leimkuehler, Thomas O.; Sheth, Rubik B.

2011-01-01

Traditionally radiator designs are based off a passive or flow through design depending on vehicle requirements. For cyclical heat loads, a novel idea of combining a full flow through radiator to a phase change material is currently being investigated. The flow through radiator can be designed for an average heat load while the phase change material can be used as a source of supplemental heat rejections when vehicle heat loads go above the average load. Furthermore, by using water as the phase change material, harmful radiation protection can be provided to the crew. This paper discusses numerous trades conducted to understand the most optimal fusible heat sink design for a particular heat load. Trades include configuration concepts, amount of phase change needed for supplemental heat rejection, and the form of interstitial material needed for optimal performance. These trades were used to culminate to a fusible heat sink design. The paper will discuss design parameters taken into account to develop an engineering development unit.

Job Aid Manuals for Phase II--DESIGN of the Instructional Systems Development Model.

ERIC Educational Resources Information Center

Schulz, Russel E.; Farrell, Jean R.

Designed to supplement the descriptive authoring flowcharts presented in a companion volume, this manual includes specific guidance, examples, and other information referred to in the flowcharts for the implementation of the second phase of the Instructional Systems Development Model (ISD). The introductory section includes definitions;…

Developing Open-Ended Questions for Surface Area and Volume of Beam

ERIC Educational Resources Information Center

Kurniawan, Henry; Putri, Ratu Ilma Indra; Hartono, Yusuf

2018-01-01

The purpose of this research was to show open-ended questions about surface area and beam volume which valid and practice, have potential effect. This research is research development which consists of two main phases: preliminary phase (preparation phase and problem design) and formative evaluation phase (evaluation and revision phases). The…

Advanced Analog Signal Processing for Fuzing Final Report CRADA No. TC-1306-96

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fu, C. Y.; Spencer, D.

The purpose of this CRADA between LLNL and Kaman Aerospace/Raymond Engineering Operations (Raymond) was to demonstrate the feasibility of using Analog/Digital Neural Network (ANN) Technology for advanced signal processing, fuzing, and other applications. This cooperation sought to Ieverage the expertise and capabilities of both parties--Raymond to develop the signature recognition hardware system, using Raymond’s extensive experience in the area of system development plus Raymond’s knowledge of military applications, and LLNL to apply ANN and related technologies to an area of significant interest to the United States government. This CRADA effort was anticipated to be a three-year project consisting of threemore » phases: Phase I, Proof-of-Principle Demonstration; Phase II, Proof-of-Design, involving the development of a form-factored integrated sensor and ANN technology processo~ and Phase III, Final Design and Release of the integrated sensor and ANN fabrication process: Under Phase I, to be conducted during calendar year 1996, Raymond was to deliver to LLNL an architecture (design) for an ANN chip. LLNL was to translate the design into a stepper mask and to produce and test a prototype chip from the Raymond design.« less

Orbit transfer rocket engine technology program. Phase 2: Advanced engine study

NASA Technical Reports Server (NTRS)

Erickson, C.; Martinez, A.; Hines, B.

1987-01-01

In Phase 2 of the Advanced Engine Study, the Failure Modes and Effects Analysis (FMEA) maintenance-driven engine design, preliminary maintenance plan, and concept for space operable disconnects generated in Phase 1 were further developed. Based on the results of the vehicle contractors Orbit Transfer Vehicle (OTV) Concept Definition and System Analysis Phase A studies, minor revisions to the engine design were made. Additional refinements in the engine design were identified through further engine concept studies. These included an updated engine balance incorporating experimental heat transfer data from the Enhanced Heat Load Thrust Chamber Study and a Rao optimum nozzle contour. The preliminary maintenance plan of Phase 1 was further developed through additional studies. These included a compilation of critical component lives and life limiters and a review of the Space Shuttle Main Engine (SSME) operations and maintenance manual in order to begin outlining the overall maintenance procedures for the Orbit Transfer Vehicle Engine and identifying technology requirements for streamlining space-based operations. Phase 2 efforts also provided further definition to the advanced fluid coupling devices including the selection and preliminary design of a preferred concept and a preliminary test plan for its further development.

Expanding the term "Design Space" in high performance liquid chromatography (I).

PubMed

Monks, K E; Rieger, H-J; Molnár, I

2011-12-15

The current article presents a novel approach to applying Quality by Design (QbD) principles to the development of high pressure reversed phase liquid chromatography (HPLC) methods. Four common critical parameters in HPLC--gradient time, temperature, pH of the aqueous eluent, and stationary phase--are evaluated within the Quality by Design framework by the means of computer modeling software and a column database, to a satisfactory degree. This work proposes the establishment of two mutually complimentary Design Spaces to fully depict a chromatographic method; one Column Design Space (CDS) and one Eluent Design Space (EDS) to describe the influence of the stationary phase and of the mobile phase on the separation selectivity, respectively. The merge of both Design Spaces into one is founded on the continuous nature of the mobile phase influence on retention and the great variety of the stationary phases available. Copyright © 2011 Elsevier B.V. All rights reserved.

Microwave monolithic integrated circuit development for future spaceborne phased array antennas

NASA Astrophysics Data System (ADS)

Anzic, G.; Kascak, T. J.; Downey, A. N.; Liu, D. C.; Connolly, D. J.

1983-12-01

The development of fully monolithic gallium arsenide (GaAs) receive and transmit modules suitable for phased array antenna applications in the 30/20 gigahertz bands is presented. Specifications and various design approaches to achieve the design goals are described. Initial design and performance of submodules and associated active and passive components are presented. A tradeoff study summary is presented highlighting the advantages of distributed amplifier approach compared to the conventional single power source designs.

Microwave monolithic integrated circuit development for future spaceborne phased array antennas

NASA Technical Reports Server (NTRS)

Anzic, G.; Kascak, T. J.; Downey, A. N.; Liu, D. C.; Connolly, D. J.

1983-01-01

The development of fully monolithic gallium arsenide (GaAs) receive and transmit modules suitable for phased array antenna applications in the 30/20 gigahertz bands is presented. Specifications and various design approaches to achieve the design goals are described. Initial design and performance of submodules and associated active and passive components are presented. A tradeoff study summary is presented highlighting the advantages of distributed amplifier approach compared to the conventional single power source designs.

Design of a fiber-optic transmitter for microwave analog transmission with high phase stability

NASA Technical Reports Server (NTRS)

Logan, R. T., Jr.; Lutes, G. F.; Primas, L. E.; Maleki, L.

1990-01-01

The principal considerations in the design of fiber-optic transmitters for highly phase-stable radio frequency and microwave analog transmission are discussed. Criteria for a fiber-optic transmitter design with improved amplitude and phase-noise performance are developed through consideration of factors affecting the phase noise, including low-frequency laser-bias supply noise, the magnitude and proximity of external reflections into the laser, and temperature excursions of the laser-transmitter package.

Streamline Your Project: A Lifecycle Model.

ERIC Educational Resources Information Center

Viren, John

2000-01-01

Discusses one approach to project organization providing a baseline lifecycle model for multimedia/CBT development. This variation of the standard four-phase model of Analysis, Design, Development, and Implementation includes a Pre-Analysis phase, called Definition, and a Post-Implementation phase, known as Maintenance. Each phase is described.…

Research safety vehicle program (Phase II) specification review. Volume II. Final technical report, Jul 1975--Nov 1976

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pugliese, S.M.

1977-02-01

In Phase I of the Research Safety Vehicle Program (RSV), preliminary design and performance specifications were developed for a mid-1980's vehicle that integrates crashworthiness and occupant safety features with material resource conservation, economy, and producibility. Phase II of the program focused on development of the total vehicle design via systems engineering and integration analyses. As part of this effort, it was necessary to continuously review the Phase I recommended performance specification in relation to ongoing design/test activities. This document contains the results of analyses of the Phase I specifications. The RSV is expected to satisfy all of the producibility andmore » safety related specifications, i.e., handling and stability systems, crashworthiness, occupant protection, pedestrian/cyclist protection, etc.« less

Space station MSFC-DPD-235/DR no. MA-05 phase C/D program development plan. Volume 2: Phase C/D, programmatic requirements

NASA Technical Reports Server (NTRS)

1971-01-01

The design plan requirements define the design implementation and control requirements for Phase C/D of the Modular Space Station Project and specifically address the Initial Space Station phase of the Space Station Program (modular). It is based primarily on the specific objective of translating the requirements of the Space Station Program, Project, Interface, and Support Requirements and preliminary contract end x item specifications into detail design of the operational systems which comprise the initial space station. This document is designed to guide aerospace contractors in the planning and bidding for Phase C/D.

Mixed response and time-to-event endpoints for multistage single-arm phase II design.

PubMed

Lai, Xin; Zee, Benny Chung-Ying

2015-06-04

The objective of phase II cancer clinical trials is to determine if a treatment has sufficient activity to warrant further study. The efficiency of a conventional phase II trial design has been the object of considerable debate, particularly when the study regimen is characteristically cytostatic. At the time of development of a phase II cancer trial, we accumulated clinical experience regarding the time to progression (TTP) for similar classes of drugs and for standard therapy. By considering the time to event (TTE) in addition to the tumor response endpoint, a mixed-endpoint phase II design may increase the efficiency and ability of selecting promising cytotoxic and cytostatic agents for further development. We proposed a single-arm phase II trial design by extending the Zee multinomial method to fully use mixed endpoints with tumor response and the TTE. In this design, the dependence between the probability of response and the TTE outcome is modeled through a Gaussian copula. Given the type I and type II errors and the hypothesis as defined by the response rate (RR) and median TTE, such as median TTP, the decision rules for a two-stage phase II trial design can be generated. We demonstrated through simulation that the proposed design has a smaller expected sample size and higher early stopping probability under the null hypothesis than designs based on a single-response endpoint or a single TTE endpoint. The proposed design is more efficient for screening new cytotoxic or cytostatic agents and less likely to miss an effective agent than the alternative single-arm design.

Vestibular Function Research (VFR) experiment. Phase B: Design definition study

NASA Technical Reports Server (NTRS)

1978-01-01

The Vestibular Functions Research (VFR) Experiment was established to investigate the neurosensory and related physiological processes believed to be associated with the space flight nausea syndrome and to develop logical means for its prediction, prevention and treatment. The VFR Project consists of ground and spaceflight experimentation using frogs as specimens. The phase B Preliminary Design Study provided for the preliminary design of the experiment hardware, preparation of performance and hardware specification and a Phase C/D development plan, establishment of STS (Space Transportation System) interfaces and mission operations, and the study of a variety of hardware, experiment and mission options. The study consist of three major tasks: (1) mission mode trade-off; (2) conceptual design; and (3) preliminary design.

CisLunar Habitat Internal Architecture Design Criteria

NASA Technical Reports Server (NTRS)

Jones, R.; Kennedy, K.; Howard, R.; Whitmore, M.; Martin, C.; Garate, J.

2017-01-01

BACKGROUND: In preparation for human exploration to Mars, there is a need to define the development and test program that will validate deep space operations and systems. In that context, a Proving Grounds CisLunar habitat spacecraft is being defined as the next step towards this goal. This spacecraft will operate differently from the ISS or other spacecraft in human history. The performance envelope of this spacecraft (mass, volume, power, specifications, etc.) is being defined by the Future Capabilities Study Team. This team has recognized the need for a human-centered approach for the internal architecture of this spacecraft and has commissioned a CisLunar Phase-1 Habitat Internal Architecture Study Team to develop a NASA reference configuration, providing the Agency with a "smart buyer" approach for future acquisition. THE CISLUNAR HABITAT INTERNAL ARCHITECTURE STUDY: Overall, the CisLunar Habitat Internal Architecture study will address the most significant questions and risks in the current CisLunar architecture, habitation, and operations concept development. This effort is achieved through definition of design criteria, evaluation criteria and process, design of the CisLunar Habitat Phase-1 internal architecture, and the development and fabrication of internal architecture concepts combined with rigorous and methodical Human-in-the-Loop (HITL) evaluations and testing of the conceptual innovations in a controlled test environment. The vision of the CisLunar Habitat Internal Architecture Study is to design, build, and test a CisLunar Phase-1 Habitat Internal Architecture that will be used for habitation (e.g. habitability and human factors) evaluations. The evaluations will mature CisLunar habitat evaluation tools, guidelines, and standards, and will interface with other projects such as the Advanced Exploration Systems (AES) Program integrated Power, Avionics, Software (iPAS), and Logistics for integrated human-in-the-loop testing. The mission of the CisLunar Habitat Internal Architecture Study is to become a forcing function to establish a common understanding of CisLunar Phase-1 Habitation Internal Architecture design criteria, processes, and tools. The scope of the CisLunar Habitat Internal Architecture study is to design, develop, demonstrate, and evaluate a Phase-1 CisLunar Habitat common module internal architecture based on design criteria agreed to by NASA, the International Partners, and Commercial Exploration teams. This task is to define the CisLunar Phase-1 Internal Architecture Government Reference Design, assist NASA in becoming a "smart buyer" for Phase-1 Habitat Concepts, and ultimately to derive standards and requirements from the Internal Architecture Design Process. The first step was to define a Habitat Internal Architecture Design Criteria and create a structured philosophy to be used by design teams as a filter by which critical aspects of consideration would be identified for the purpose of organizing and utilizing interior spaces. With design criteria in place, the team will develop a series of iterative internal architecture concept designs which will be assessed by means of an evaluation criteria and process. These assessments will successively drive and refine the design, leading to the combination and down-selection of design concepts. A single refined reference design configuration will be developed into in a medium-to-high fidelity mockup. A multi-day human-in-the-loop mission test will fully evaluate the reference design and validate its configuration. Lessons learned from the design and evaluation will enable the team to identify appropriate standards for Phase-1 CisLunar Habitat Internal Architecture and will enable NASA to develop derived requirements in support of maturing CisLunar Habitation capabilities. This paper will describe the criteria definition process, workshop event, and resulting CisLunar Phase-1 Habitat Internal Architecture Design Criteria.

Satellite Systems Design/Simulation Environment: A Systems Approach to Pre-Phase A Design

NASA Technical Reports Server (NTRS)

Ferebee, Melvin J., Jr.; Troutman, Patrick A.; Monell, Donald W.

1997-01-01

A toolset for the rapid development of small satellite systems has been created. The objective of this tool is to support the definition of spacecraft mission concepts to satisfy a given set of mission and instrument requirements. The objective of this report is to provide an introduction to understanding and using the SMALLSAT Model. SMALLSAT is a computer-aided Phase A design and technology evaluation tool for small satellites. SMALLSAT enables satellite designers, mission planners, and technology program managers to observe the likely consequences of their decisions in terms of satellite configuration, non-recurring and recurring cost, and mission life cycle costs and availability statistics. It was developed by Princeton Synergetic, Inc. and User Systems, Inc. as a revision of the previous TECHSAT Phase A design tool, which modeled medium-sized Earth observation satellites. Both TECHSAT and SMALLSAT were developed for NASA.

NASA Research Announcement Phase 1 Report and Phase 2 Proposal for the Development of a Power Assisted Space Suit Glove Assembly

NASA Technical Reports Server (NTRS)

Cadogan, Dave; Lingo, Bob

1996-01-01

In July of 1996, ILC Dover was awarded Phase 1 of a contract for NASA to develop a prototype Power Assisted Space Suit glove to enhance the performance of astronauts during Extra-Vehicular Activity (EVA). This report summarizes the work performed to date on Phase 1, and details the work to be conducted on Phase 2 of the program. Phase 1 of the program consisted of research and review of related technical sources, concept brainstorming, baseline design development, modeling and analysis, component mock-up testing, and test data analysis. ILC worked in conjunction with the University of Maryland's Space Systems Laboratory (SSL) to develop the power assisted glove. Phase 2 activities will focus on the design maturation and the manufacture of a working prototype system. The prototype will be tested and evaluated in conjunction with existing space suit glove technology to determine the performance enhancement anticipated with the implementation of the power assisted joint technology in space suit gloves.

Phase I, open-cycle absorption solar cooling. Part IV. Executive summary analysis and resolution of critical issues and recommendations for Phase II. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wood, B.D.

The objective of this project is to advance lower cost solar cooling technology with the feasibility analysis, design and evaluation of proof-of-concept open cycle solar cooling concepts. The work is divided into three phases, with planned completion of each phase before proceeding with the following phase: Phase I - performance/economic/environmental related analysis and exploratory studies; Phase II - design and construction of an experimental system, including evaluative testing; Phase III - extended system testing during operation and engineering modifications as required. For Phase I, analysis and resolution of critical issues were completed with the objective of developing design specifications formore » an improved prototype OCA system.« less

Investigating the effects of roadway design on driver behavior : applications for Minnesota highway design

DOT National Transportation Integrated Search

1999-02-01

This report details a project to study the relationship between highway design and human behavior as influenced by roadside environments. The project was developed in two phases. In the visualization phase, computer simulation was used to model an ac...

Bridge-in-a-Backpack(TM). Task 2 : reduction of costs through design modifications and optimization.

DOT National Transportation Integrated Search

2011-09-01

The cost effective use of FRP composites in infrastructure requires the efficient use of the : composite materials in the design. Previous work during the development phase and : demonstration phase illustrated the need to refine the design methods f...

Microwave monolithic integrated circuit development for future spaceborne phased array antennas

NASA Astrophysics Data System (ADS)

Anzic, G.; Kascak, T. J.; Downey, A. N.; Liu, D. C.; Connolly, D. J.

The development of fully monolithic gallium arsenide (GaAs) receive and transmit modules suitable for phased array antenna applications in the 30/20 gigahertz bands is presented. Specifications and various design approaches to achieve the design goals are described. Initial design and performance of submodules and associated active and passive components are presented. A tradeoff study summary is presented, highlighting the advantages of a distributed amplifier approach compared to the conventional single power source designs. Previously announced in STAR as N84-13399

Microwave monolithic integrated circuit development for future spaceborne phased array antennas

NASA Technical Reports Server (NTRS)

Anzic, G.; Kascak, T. J.; Downey, A. N.; Liu, D. C.; Connolly, D. J.

1984-01-01

The development of fully monolithic gallium arsenide (GaAs) receive and transmit modules suitable for phased array antenna applications in the 30/20 gigahertz bands is presented. Specifications and various design approaches to achieve the design goals are described. Initial design and performance of submodules and associated active and passive components are presented. A tradeoff study summary is presented, highlighting the advantages of a distributed amplifier approach compared to the conventional single power source designs. Previously announced in STAR as N84-13399

STEM Workforce Pipeline

DTIC Science & Technology

2013-07-30

more about STEM. From museums, to gardens, to planetariums and more, Places to Go mobilizes people to explore the STEM resources offered by their...Works website was developed utilizing a phased approach. This approach allowed for informed, periodic updates to the structure, design, and backend ...our web development team, throughout this phase. A significant amount of backend development work on the website, as well as design work was completed

Phase-locked loops. [analog, hybrid, discrete and digital systems

NASA Technical Reports Server (NTRS)

Gupta, S. C.

1974-01-01

The basic analysis and design procedures are described for the realization of analog phase-locked loops (APLL), hybrid phase-locked loops (HPLL), discrete phase-locked loops, and digital phase-locked loops (DPLL). Basic configurations are diagrammed, and performance curves are given. A discrete communications model is derived and developed. The use of the APLL as an optimum angle demodulator and the Kalman-Bucy approach to APLL design are discussed. The literature in the area of phase-locked loops is reviewed, and an extensive bibliography is given. Although the design of APLLs is fairly well documented, work on discrete, hybrid, and digital PLLs is scattered, and more will have to be done in the future to pinpoint the formal design of DPLLs.

History and Benefits of Engine Level Testing Throughout the Space Shuttle Main Engine Program

NASA Technical Reports Server (NTRS)

VanHooser, Katherine; Kan, Kenneth; Maddux, Lewis; Runkle, Everett

2010-01-01

Rocket engine testing is important throughout a program s life and is essential to the overall success of the program. Space Shuttle Main Engine (SSME) testing can be divided into three phases: development, certification, and operational. Development tests are conducted on the basic design and are used to develop safe start and shutdown transients and to demonstrate mainstage operation. This phase helps form the foundation of the program, demands navigation of a very steep learning curve, and yields results that shape the final engine design. Certification testing involves multiple engine samples and more aggressive test profiles that explore the boundaries of the engine to vehicle interface requirements. The hardware being tested may have evolved slightly from that in the development phase. Operational testing is conducted with mature hardware and includes acceptance testing of flight assets, resolving anomalies that occur in flight, continuing to expand the performance envelope, and implementing design upgrades. This paper will examine these phases of testing and their importance to the SSME program. Examples of tests conducted in each phase will also be presented.

Design of Phase I Combination Trials: Recommendations of the Clinical Trial Design Task Force of the NCI Investigational Drug Steering Committee

PubMed Central

Paller, Channing J.; Bradbury, Penelope A.; Ivy, S. Percy; Seymour, Lesley; LoRusso, Patricia M.; Baker, Laurence; Rubinstein, Larry; Huang, Erich; Collyar, Deborah; Groshen, Susan; Reeves, Steven; Ellis, Lee M.; Sargent, Daniel J.; Rosner, Gary L.; LeBlanc, Michael L.; Ratain, Mark J.

2014-01-01

Anticancer drugs are combined in an effort to treat a heterogeneous tumor or to maximize the pharmacodynamic effect. The development of combination regimens, while desirable, poses unique challenges. These include the selection of agents for combination therapy that may lead to improved efficacy while maintaining acceptable toxicity, the design of clinical trials that provide informative results for individual agents and combinations, and logistical and regulatory challenges. The phase 1 trial is often the initial step in the clinical evaluation of a combination regimen. In view of the importance of combination regimens and the challenges associated with developing them, the Clinical Trial Design (CTD) Task Force of the National Cancer Institute (NCI) Investigational Drug Steering Committee developed a set of recommendations for the phase 1 development of a combination regimen. The first two recommendations focus on the scientific rationale and development plans for the combination regimen; subsequent recommendations encompass clinical design aspects. The CTD Task Force recommends that selection of the proposed regimens be based on a biological or pharmacological rationale supported by clinical and/or robust and validated preclinical evidence, and accompanied by a plan for subsequent development of the combination. The design of the phase 1 clinical trial should take into consideration the potential pharmacokinetic and pharmacodynamic interactions as well as overlapping toxicity. Depending on the specific hypothesized interaction, the primary endpoint may be dose optimization, pharmacokinetics, and/or pharmacodynamic (i.e., biomarker). PMID:25125258

MOD-5A wind turbine generator program design report: Volume 1: Executive Summary

NASA Technical Reports Server (NTRS)

1984-01-01

The design, development and analysis of the 7.3 MW MOD-5A wind turbine generator covering work performed between July 1980 and June 1984 is discussed. The report is divided into four volumes: Volume 1 summarizes the entire MOD-5A program, Volume 2 discusses the conceptual and preliminary design phases, Volume 3 describes the final design of the MOD-5A, and Volume 4 contains the drawings and specifications developed for the final design. Volume 1, the Executive Summary, summarizes all phases of the MOD-5A program. The performance and cost of energy generated by the MOD-5A are presented. Each subsystem - the rotor, drivetrain, nacelle, tower and foundation, power generation, and control and instrumentation subsystems - is described briefly. The early phases of the MOD-5A program, during which the design was analyzed and optimized, and new technologies and materials were developed, are discussed. Manufacturing, quality assurance, and safety plans are presented. The volume concludes with an index of volumes 2 and 3.

Communications technology satellite output-tube design and development

NASA Technical Reports Server (NTRS)

Connolly, D. J.; Forman, R.; Jones, C. L.; Kosmahl, H.; Sharp, G. R.

1977-01-01

The design and development of a 200-watt-output, traveling-wave tube (TWT) for the Communications Technology Satellite (CTS) is discussed, with emphasis on the design evolution during the manufacturing phase of the development program. Possible further improvements to the tube design are identified.

Sensitivity of Space Shuttle Weight and Cost to Structure Subsystem Weights

NASA Technical Reports Server (NTRS)

Wedge, T. E.; Williamson, R. P.

1973-01-01

Quantitative relationships between changes in space shuttle weights and costs with changes in weight of various portions of space shuttle structural subsystems are investigated. These sensitivity relationships, as they apply at each of three points in the development program (preliminary design phase, detail design phase, and test/operational phase) have been established for five typical space shuttle designs, each of which was responsive to the missions in the NASA Shuttle RFP, and one design was that selected by NASA.

[Construction of an educational technology for teaching about nursing on peripheral venipuncture].

PubMed

Frota, Natasha Marques; Barros, Lívia Moreira; de Araújo, Thiago Moura; Caldini, Luana Nunes; do Nascimento, Jennara Cândido; Caetano, Joselany Afio

2013-06-01

The aim of the study was to describe the construction of a course on peripheral venipuncture using the Information and Communication Technologies. This is a methodological research, developed at the Federal University of Ceara from January to March 2012. The construction phases are: the analysis, design and development according to the theoretical framework of Galvis-Panqueva. In the analysis, objectives, content target audience, the study environment and technology infrastructure were delimited. During the design phase the environment interface and navigation structure of the course were evaluated. The development consisted in the materialization of all that was designed in the previous phase Once all three phases of construction of the course were conducted it was available in the Virtual Learning Environment SOLAR. The finalproduct of the course is presented as support of nursing students and consequently the training of future nurses in their care practice on peripheral venipuncture.

The Seasat surface truth experiments

NASA Technical Reports Server (NTRS)

Shemdin, O. H.

1976-01-01

A surface truth program for Seasat A is formulated in two phases: pre- and post-launch. The pre-launch phase (which includes the Marineland experiments, the JONSWAP-75 experiment, the West Coast experiment, and the altimeter experiment) is designed to provide data from aircraft over instrumented ocean sites during desirable geophysical events. The objective is to gather sufficient data for the development of algorithms which transfer space data into geophysical variables useful for applications. In the post-launch phase, the surface truth program is designed to verify and improve the algorithms developed in the pre-launch phase and also to evaluate the performance of spaceborne sensors.

Feasibility of developing a portable driver performance data acquisition system for human factors research: Technical tasks. Volume 1

DOE Office of Scientific and Technical Information (OSTI.GOV)

Carter, R.J.; Barickman, F.S.; Spelt, P.F.

1998-01-01

A two-phase, multi-year research program entitled ``development of a portable driver performance data acquisition system for human factors research`` was recently completed. The primary objective of the project was to develop a portable data acquisition system for crash avoidance research (DASCAR) that will allow drive performance data to be collected using a large variety of vehicle types and that would be capable of being installed on a given vehicle type within a relatively short-time frame. During phase 1 a feasibility study for designing and fabricating DASCAR was conducted. In phase 2 of the research DASCAR was actually developed and validated.more » This technical memorandum documents the results from the feasibility study. It is subdivided into three volumes. Volume one (this report) addresses the last five items in the phase 1 research and the first issue in the second phase of the project. Volumes two and three present the related appendices, and the design specifications developed for DASCAR respectively. The six tasks were oriented toward: identifying parameters and measures; identifying analysis tools and methods; identifying measurement techniques and state-of-the-art hardware and software; developing design requirements and specifications; determining the cost of one or more copies of the proposed data acquisition system; and designing a development plan and constructing DASCAR. This report also covers: the background to the program; the requirements for the project; micro camera testing; heat load calculations for the DASCAR instrumentation package in automobile trunks; phase 2 of the research; the DASCAR hardware and software delivered to the National Highway Traffic Safety Administration; and crash avoidance problems that can be addressed by DASCAR.« less

Brayton advanced heat receiver development program

NASA Technical Reports Server (NTRS)

Heidenreich, G. R.; Downing, R. S.; Lacey, Dovie E.

1989-01-01

NASA Lewis Research Center is managing an advanced solar dynamic (ASD) space power program. The objective of the ASD program is to develop small and lightweight solar dynamic systems which show significant improvement in efficiency and specific mass over the baseline design derived from the Space Station Freedom technology. The advanced heat receiver development program is a phased program to design, fabricate and test elements of a 7-kWe heat-receiver/thermal-energy-storage subsystem. Receivers for both Brayton and Stirling heat engines are being developed under separate contracts. Phase I, described here, is the current eighteen month effort to design and perform critical technology experiments on innovative concepts designed to reduce mass without compromising thermal efficiency and reliability.

Space station WP-04 power system. Volume 1: Executive summary

NASA Technical Reports Server (NTRS)

Hallinan, G. J.

1987-01-01

Major study activities and results of the phase B study contract for the preliminary design of the space station Electrical Power System (EPS) are summarized. The areas addressed include the general system design, man-tended option, automation and robotics, evolutionary growth, software development environment, advanced development, customer accommodations, operations planning, product assurance, and design and development phase planning. The EPS consists of a combination photovoltaic and solar dynamic power generation subsystem and a power management and distribution (PMAD) subsystem. System trade studies and costing activities are also summarized.

A Low Temperature, Reverse Brayton Cryocooler

NASA Technical Reports Server (NTRS)

Swift, Walter L.

2001-01-01

This status report covers the fifty-second month of a project to develop a low temperature, reverse-Brayton cryocooler using turbomachines. This program consists of a Basic Phase and four Option Phases. Each of the Phases is directed to a particular load/temperature combination. The technology and fundamental design features of the components used in these systems are related but differ somewhat in size, speed, and some details in physical geometry. Each of the Phases can be carried out independently of the others, except that all of the Phases rely on the technology developed and demonstrated during the Basic Phase. The Basic Phase includes the demonstration of a critical component and the production of a prototype model cryocooler. The critical technology demonstration will be the test of a small turboalternator over a range of conditions at temperatures down to 6 K. These tests will provide design verification data useful for the further design of the other coolers. The prototype model cooler will be designed to provide at least 5 mW of cooling at 6 K. The heat rejection temperature for this requirement is 220 K or greater. The input power to the system at these conditions is to be less than 60 W.

Space Station Furnace Facility. Volume 1: Requirements definition and conceptual design study, executive summary

NASA Technical Reports Server (NTRS)

1992-01-01

The Space Station Freedom Furnace (SSFF) Study was awarded on June 2, 1989, to Teledyne Brown Engineering (TBE) to define an advanced facility for materials research in the microgravity environment of Space Station Freedom (SSF). The SSFF will be designed for research in the solidification of metals and alloys, the crystal growth of electronic and electro-optical materials, and research in glasses and ceramics. The SSFF is one of the first 'facility' class payloads planned by the Microgravity Science and Applications Division (MSAD) of the Office of Space Science and Applications of NASA Headquarters. This facility is planned for early deployment during man-tended operations of the SSF with continuing operations through the Permanently Manned Configuration (PMC). The SSFF will be built around a general 'Core' facility which provides common support functions not provided by SSF, common subsystems which are best centralized, and common subsystems which are best distributed with each experiment module. The intent of the facility approach is to reduce the overall cost associated with implementing and operating a variety of experiments. This is achieved by reducing the launch mass and simplifying the hardware development and qualification processes associated with each experiment. The Core will remain on orbit and will require only periodic maintenance and upgrading while new Furnace Modules, samples, and consumables are developed, qualified, and transported to the SSF. The SSFF Study was divided into two phases: phase 1, a definition study phase, and phase 2, a design and development phase. The definition phase 1 is addressed. Phase 1 was divided into two parts. In the first part, the basic part of the effort, covered the preliminary definition and assessment of requirements; conceptual design of the SSFF; fabrication of mockups; and the preparation for and support of the Conceptual Design Review (CoDR). The second part, the option part, covered requirements update and documentation; refinement of the selected conceptual design through additional trades and analyses; design, fabrication, and test of the Development Model; and design, fabrication, and test of the Interrack Demonstration Unit; and support of the requirements definition review (RDR). The purpose of part 2 was to prove concept feasibility.

Space Station - An integrated approach to operational logistics support

NASA Technical Reports Server (NTRS)

Hosmer, G. J.

1986-01-01

Development of an efficient and cost effective operational logistics system for the Space Station will require logistics planning early in the program's design and development phase. This paper will focus on Integrated Logistics Support (ILS) Program techniques and their application to the Space Station program design, production and deployment phases to assure the development of an effective and cost efficient operational logistics system. The paper will provide the methodology and time-phased programmatic steps required to establish a Space Station ILS Program that will provide an operational logistics system based on planned Space Station program logistics support.

Project: MOBILITY. Introduction and Summary.

ERIC Educational Resources Information Center

Fresno City Coll., CA.

This report summarizes a project designed to develop vocational educational programs and services for educationally disadvantaged and physically handicapped students at Fresno City College, California. The introduction provides an overview of the two phases of the project: phase I, a needs assessment; and phase II, curriculum development and…

ADVANCED WORKER PROTECTION SYSTEM

DOE Office of Scientific and Technical Information (OSTI.GOV)

Judson Hedgehock

2001-03-16

From 1993 to 2000, OSS worked under a cost share contract from the Department of Energy (DOE) to develop an Advanced Worker Protection System (AWPS). The AWPS is a protective ensemble that provides the user with both breathing air and cooling for a NIOSH-rated duration of two hours. The ensemble consists of a liquid air based backpack, a Liquid Cooling Garment (LCG), and an outer protective garment. The AWPS project was divided into two phases. During Phase 1, OSS developed and tested a full-scale prototype AWPS. The testing showed that workers using the AWPS could work twice as long asmore » workers using a standard SCBA. The testing also provided performance data on the AWPS in different environments that was used during Phase 2 to optimize the design. During Phase 1, OSS also performed a life-cycle cost analysis on a representative clean up effort. The analysis indicated that the AWPS could save the DOE millions of dollars on D and D activities and improve the health and safety of their workers. During Phase 2, OSS worked to optimize the AWPS design to increase system reliability, to improve system performance and comfort, and to reduce the backpack weight and manufacturing costs. To support this design effort, OSS developed and tested several different generations of prototype units. Two separate successful evaluations of the ensemble were performed by the International Union of Operation Engineers (IUOE). The results of these evaluations were used to drive the design. During Phase 2, OSS also pursued certifying the AWPS with the applicable government agencies. The initial intent during Phase 2 was to finalize the design and then to certify the system. OSS and Scott Health and Safety Products teamed to optimize the AWPS design and then certify the system with the National Institute of Occupational Health and Safety (NIOSH). Unfortunately, technical and programmatic difficulties prevented us from obtaining NIOSH certification. Despite the inability of NIOSH to certify the design, OSS was able to develop and successfully test, in both the lab and in the field, a prototype AWPS. They clearly demonstrated that a system which provides cooling can significantly increase worker productivity by extending the time they can function in a protective garment. They were also able to develop mature outer garment and LCG designs that provide considerable benefits over current protective equipment, such as self donning and doffing, better visibility, and machine washable. A thorough discussion of the activities performed during Phase 1 and Phase 2 is presented in the AWPS Final Report. The report also describes the current system design, outlines the steps needed to certify the AWPS, discusses the technical and programmatic issues that prevented the system from being certified, and presents conclusions and recommendations based upon the seven year effort.« less

The samara spacecraft: Design and development of a self-stabilizing, auto-rotating, distributed sensing system

NASA Astrophysics Data System (ADS)

Lalloobhai, Amit Desai

The objective of this research is the design and development of a self-stabilizing re-entry vehicle that closely resembles naturally occurring seeds in nature. It was hypothesized that a femto-satellite with a shape of a samara could self stabilize and passively generate lift, as well as transmit a signal during its descent through the atmosphere. The research included a conceptual design phase and a preliminary design phase that entailed analytic simulations, and an experimental demonstration. The goal was to investigate the feasibility of developing the above-mentioned femto-vehicle that could increase the range capability of its descent to maximize data capture.

Development and testing of a high cycle life 30 A-h sealed AgO-Zn battery

NASA Technical Reports Server (NTRS)

Bogner, R. S.

1972-01-01

A two-phase program was initiated to investigate design parameters and technology to develop an improved AgO-Zn battery. The basic performance goal was 100 charge/discharge cycles (22 h/2 h) at 50 percent depth of discharge following a six-month period of charged stand at room temperature. Phase 1, cell evaluation, involved testing 70 cells in five-cell groups. The major design variables were active material ratios, electrolyte concentrations, separator systems, and negative plate shape. Phase 1 testing showed that cycle life could be improved 10 percent to 20 percent by using greater ratios of zinc to silver oxide and higher electrolyte concentrations. Wedge-shaped negatives increased cycle life by nearly 100 percent. Phase 2 battery evaluation, which was initiated before the Phase 1 results were known completely, involved evaluation of six designs as 19-cell batteries. Only one battery exceeded 100 cycles following nine months charged stand.

Reflector Technology Development and System Design for Concentrating Solar Power Technologies

DOE Office of Scientific and Technical Information (OSTI.GOV)

Adam Schaut

2011-12-30

Alcoa began this program in March of 2008 with the goal of developing and validating an advanced CSP trough design to lower the levelized cost of energy (LCOE) as compared to existing glass based, space-frame trough technology. In addition to showing a pathway to a significant LCOE reduction, Alcoa also desired to create US jobs to support the emerging CSP industry. Alcoa's objective during Phase I: Concept Feasibility was to provide the DOE with a design approach that demonstrates significant overall system cost savings without sacrificing performance. Phase I consisted of two major tasks; reflector surface development and system conceptmore » development. Two specific reflective surface technologies were investigated, silver metallized lamination, and thin film deposition both applied on an aluminum substrate. Alcoa prepared samples; performed test validation internally; and provided samples to the NREL for full-spectrum reflectivity measurements. The final objective was to report reflectivity at t = 0 and the latest durability results as of the completion of Phase 1. The target criteria for reflectance and durability were as follows: (1) initial (t = 0), hemispherical reflectance >93%, (2) initial spectral reflectance >90% for 25-mrad reading and >87% for 7-mrad reading, and (3) predicted 20 year durability of less than 5% optical performance drop. While the results of the reflective development activities were promising, Alcoa was unable to down-select on a reflective technology that met the target criteria. Given the progress and potential of both silver film and thin film technologies, Alcoa continued reflector surface development activities in Phase II. The Phase I concept development activities began with acquiring baseline CSP system information from both CSP Services and the DOE. This information was used as the basis to develop conceptual designs through ideation sessions. The concepts were evaluated based on estimated cost and high-level structural performance. The target criteria for the concept development was to achieve a solar field cost savings of 25%-50% thereby meeting or exceeding the DOE solar field cost savings target of $350/m2. After evaluating various structural design approaches, Alcoa down-selected to a monocoque, dubbed Wing Box, design that utilizes the reflective surface as a structural, load carrying member. The cost and performance potential of the Wing Box concept was developed via initial finite element analysis (FEA) and cost modeling. The structural members were sized through material utilization modeling when subjected to representative loading conditions including wind loading. Cost modeling was utilized to refine potential manufacturing techniques that could be employed to manufacture the structural members. Alcoa concluded that an aluminum intensive collector design can achieve significant cost savings without sacrificing performance. Based on the cost saving potential of this Concept Feasibility study, Alcoa recommended further validation of this CSP approach through the execution of Phase II: Design and Prototype Development. Alcoa Phase II objective was to provide the DOE with a validated CSP trough design that demonstrates significant overall system cost savings without sacrificing performance. Phase II consisted of three major tasks; Detail System Design, Prototype Build, and System Validation. Additionally, the reflector surface development that began in Phase I was continued in Phase II. After further development work, Alcoa was unable to develop a reflective technology that demonstrated significant performance or cost benefits compared to commercially available CSP reflective products. After considering other commercially available reflective surfaces, Alcoa selected Alano's MIRO-SUN product for use on the full scale prototype. Although MIRO-SUN has a lower specular reflectivity compared to other options, its durability in terms of handling, cleaning, and long-term reflectivity was deemed the most important attribute to successfully validate Alcoa's advanced trough architecture. To validate the performance of the Wing Box trough, a 6 meter aperture by 14 meter long prototype trough was built. For ease of shipping to and assembly at NREL's test facility, the prototype was fabricated in two half modules and joined along the centerline to create the Wing Box trough. The trough components were designed to achieve high precision of the reflective surface while leveraging high volume manufacturing and assembly techniques.« less

Advanced Envelope Research for Factory Built Housing, Phase 3. Design Development and Prototyping

DOE Office of Scientific and Technical Information (OSTI.GOV)

Levy, E.; Kessler, B.; Mullens, M.

2014-01-01

The Advanced Envelope Research effort will provide factory homebuilders with high performance, cost-effective alternative envelope designs. In the near term, these technologies will play a central role in meeting stringent energy code requirements. For manufactured homes, the thermal requirements, last updated by statute in 1994, will move up to the more rigorous IECC 2012 levels in 2013, the requirements of which are consistent with site built and modular housing. This places added urgency on identifying envelope technologies that the industry can implement in the short timeframe. The primary goal of this research is to develop wall designs that meet themore » thermal requirements based on 2012 IECC standards. Given the affordable nature of manufactured homes, impact on first cost is a major consideration in developing the new envelope technologies. This work is part of a four-phase, multi-year effort. Phase 1 identified seven envelope technologies and provided a preliminary assessment of three selected methods for building high performance wall systems. Phase 2 focused on the development of viable product designs, manufacturing strategies, addressing code and structural issues, and cost analysis of the three selected options. An industry advisory committee helped critique and select the most viable solution to move further in the research -- stud walls with continuous exterior insulation. Phase 3, the subject of the current report, focused on the design development of the selected wall concept and explored variations on the use of exterior foam insulation. The scope also included material selection, manufacturing and cost analysis, and prototyping and testing.« less

Advanced Envelope Research for Factory Built Housing, Phase 3 -- Design Development and Prototyping

DOE Office of Scientific and Technical Information (OSTI.GOV)

Levy, E.; Kessler, B.; Mullens, M.

2014-01-01

The Advanced Envelope Research effort will provide factory homebuilders with high performance, cost-effective alternative envelope designs. In the near term, these technologies will play a central role in meeting stringent energy code requirements. For manufactured homes, the thermal requirements, last updated by statute in 1994, will move up to the more rigorous IECC 2012 levels in 2013, the requirements of which are consistent with site built and modular housing. This places added urgency on identifying envelope technologies that the industry can implement in the short timeframe. The primary goal of this research is to develop wall designs that meet themore » thermal requirements based on 2012 IECC standards. Given the affordable nature of manufactured homes, impact on first cost is a major consideration in developing the new envelope technologies. This work is part of a four-phase, multi-year effort. Phase 1 identified seven envelope technologies and provided a preliminary assessment of three selected methods for building high performance wall systems. Phase 2 focused on the development of viable product designs, manufacturing strategies, addressing code and structural issues, and cost analysis of the three selected options. An industry advisory committee helped critique and select the most viable solution to move further in the research -- stud walls with continuous exterior insulation. Phase 3, the subject of the current report, focused on the design development of the selected wall concept and explored variations on the use of exterior foam insulation. The scope also included material selection, manufacturing and cost analysis, and prototyping and testing.« less

A Human-Centered Design Methodology to Enhance the Usability, Human Factors, and User Experience of Connected Health Systems: A Three-Phase Methodology

PubMed Central

Harte, Richard; Glynn, Liam; Rodríguez-Molinero, Alejandro; Baker, Paul MA; Scharf, Thomas; ÓLaighin, Gearóid

2017-01-01

Background Design processes such as human-centered design, which involve the end user throughout the product development and testing process, can be crucial in ensuring that the product meets the needs and capabilities of the user, particularly in terms of safety and user experience. The structured and iterative nature of human-centered design can often present a challenge when design teams are faced with the necessary, rapid, product development life cycles associated with the competitive connected health industry. Objective We wanted to derive a structured methodology that followed the principles of human-centered design that would allow designers and developers to ensure that the needs of the user are taken into account throughout the design process, while maintaining a rapid pace of development. In this paper, we present the methodology and its rationale before outlining how it was applied to assess and enhance the usability, human factors, and user experience of a connected health system known as the Wireless Insole for Independent and Safe Elderly Living (WIISEL) system, a system designed to continuously assess fall risk by measuring gait and balance parameters associated with fall risk. Methods We derived a three-phase methodology. In Phase 1 we emphasized the construction of a use case document. This document can be used to detail the context of use of the system by utilizing storyboarding, paper prototypes, and mock-ups in conjunction with user interviews to gather insightful user feedback on different proposed concepts. In Phase 2 we emphasized the use of expert usability inspections such as heuristic evaluations and cognitive walkthroughs with small multidisciplinary groups to review the prototypes born out of the Phase 1 feedback. Finally, in Phase 3 we emphasized classical user testing with target end users, using various metrics to measure the user experience and improve the final prototypes. Results We report a successful implementation of the methodology for the design and development of a system for detecting and predicting falls in older adults. We describe in detail what testing and evaluation activities we carried out to effectively test the system and overcome usability and human factors problems. Conclusions We feel this methodology can be applied to a wide variety of connected health devices and systems. We consider this a methodology that can be scaled to different-sized projects accordingly. PMID:28302594

Design of a Model Management Information System (MIS) for California's Regional Occupational Centers and Programs. Final Report.

ERIC Educational Resources Information Center

Dick, James C.; And Others

The management information system (MIS) development project for California's Regional Occupational Centers and Programs (ROC/Ps) was conducted in 3 phases over a 12-month period. Phase I involved a literature review and field study to match MIS design features and development strategy with existing conditions in ROC/Ps. A decision support system…

Moving formal methods into practice. Verifying the FTPP Scoreboard: Results, phase 1

NASA Technical Reports Server (NTRS)

Srivas, Mandayam; Bickford, Mark

1992-01-01

This report documents the Phase 1 results of an effort aimed at formally verifying a key hardware component, called Scoreboard, of a Fault-Tolerant Parallel Processor (FTPP) being built at Charles Stark Draper Laboratory (CSDL). The Scoreboard is part of the FTPP virtual bus that guarantees reliable communication between processors in the presence of Byzantine faults in the system. The Scoreboard implements a piece of control logic that approves and validates a message before it can be transmitted. The goal of Phase 1 was to lay the foundation of the Scoreboard verification. A formal specification of the functional requirements and a high-level hardware design for the Scoreboard were developed. The hardware design was based on a preliminary Scoreboard design developed at CSDL. A main correctness theorem, from which the functional requirements can be established as corollaries, was proved for the Scoreboard design. The goal of Phase 2 is to verify the final detailed design of Scoreboard. This task is being conducted as part of a NASA-sponsored effort to explore integration of formal methods in the development cycle of current fault-tolerant architectures being built in the aerospace industry.

L1C signal design options

USGS Publications Warehouse

Betz, J.W.; Cahn, C.R.; Dafesh, P.A.; Hegarty, C.J.; Hudnut, K.W.; Jones, A.J.; Keegan, R.; Kovach, K.; Lenahan, L.S.; Ma, H.H.; Rushanan, J.J.; Stansell, T.A.; Wang, C.C.; Yi, S.K.

2006-01-01

Design activities for a new civil signal centered at 1575.42 MHz, called L1C, began in 2003, and the Phase 1 effort was completed in 2004. The L1C signal design has evolved and matured during a Phase 2 design activity that began in 2005. Phase 2 has built on the initial design activity, guided by responses to international user surveys conducted during Phase 1. A common core of signal characteristics has been developed to provide advances in robustness and performance. The Phase 2 activity produced five design options, all drawing upon the core signal characteristics, while representing different blends of characteristics and capabilities. A second round of international user surveys was completed to solicit advice concerning these design options. This paper provides an update of the L1C design process, and describes the current L1C design options. Initial performance estimates are presented for each design option, displaying trades between signal tracking robustness, the speed and robustness of clock and ephemeris data, and the rate and robustness of other data message contents. Planned remaining activities are summarized, leading to optimization of the L1C design.

Improved quality-by-design compliant methodology for method development in reversed-phase liquid chromatography.

PubMed

Debrus, Benjamin; Guillarme, Davy; Rudaz, Serge

2013-10-01

A complete strategy dedicated to quality-by-design (QbD) compliant method development using design of experiments (DOE), multiple linear regressions responses modelling and Monte Carlo simulations for error propagation was evaluated for liquid chromatography (LC). The proposed approach includes four main steps: (i) the initial screening of column chemistry, mobile phase pH and organic modifier, (ii) the selectivity optimization through changes in gradient time and mobile phase temperature, (iii) the adaptation of column geometry to reach sufficient resolution, and (iv) the robust resolution optimization and identification of the method design space. This procedure was employed to obtain a complex chromatographic separation of 15 antipsychotic basic drugs, widely prescribed. To fully automate and expedite the QbD method development procedure, short columns packed with sub-2 μm particles were employed, together with a UHPLC system possessing columns and solvents selection valves. Through this example, the possibilities of the proposed QbD method development workflow were exposed and the different steps of the automated strategy were critically discussed. A baseline separation of the mixture of antipsychotic drugs was achieved with an analysis time of less than 15 min and the robustness of the method was demonstrated simultaneously with the method development phase. Copyright © 2013 Elsevier B.V. All rights reserved.

NOx Emissions Characteristics and Correlation Equations of Two P and W's Axially Staged Sector Combustors Developed Under NASA Environmentally Responsible Aviation (ERA) Project

NASA Technical Reports Server (NTRS)

He, Zhuohui J.

2017-01-01

Two P&W (Pratt & Whitney)'s axially staged sector combustors have been developed under NASA's Environmentally Responsible Aviation (ERA) project. One combustor was developed under ERA Phase I, and the other was developed under ERA Phase II. Nitrogen oxides (NOx) emissions characteristics and correlation equations for these two sector combustors are reported in this article. The Phase I design was to optimize the NOx emissions reduction potential, while the Phase II design was more practical and robust. Multiple injection points and fuel staging strategies are used in the combustor design. Pilot-stage injectors are located on the front dome plate of the combustor, and main-stage injectors are positioned on the top and bottom (Phase I) or on the top only (Phase II) of the combustor liners downstream. Low power configuration uses only pilot-stage injectors. Main-stage injectors are added to high power configuration to help distribute fuel more evenly and achieve lean burn throughout the combustor yielding very low NOx emissions. The ICAO (International Civil Aviation Organization) landing-takeoff NOx emissions are verified to be 88 percent (Phase I) and 76 percent (Phase II) under the ICAO CAEP/6 (Committee on Aviation Environmental Protection 6th Meeting) standard, exceeding the ERA project goal of 75 percent reduction, and the combustors proved to have stable combustion with room to maneuver on fuel flow splits for operability.

Superfluid Helium Tanker (SFHT) study

NASA Technical Reports Server (NTRS)

1988-01-01

The accomplishments and recommendations of the two-phase Superfluid Helium Tanker (SFHT) study are presented. During the first phase of the study, the emphasis was on defining a comprehensive set of user requirements, establishing SFHT interface parameters and design requirements, and selecting a fluid subsystem design concept. During the second phase, an overall system design concept was constructed based on appropriate analyses and more detailed definition of requirements. Modifications needed to extend the baseline for use with cryogens other than SFHT have been determined, and technology development needs related to the recommended design have been assessed.

Development of Problem-Based Learning Oriented Teaching Learning Materials to Facilitate Students’ Mastery of Concept and Critical Thinking Skill

NASA Astrophysics Data System (ADS)

Reza, M.; Ibrahim, M.; Rahayu, Y. S.

2018-01-01

This research aims to develop problem-based learning oriented teaching materials to improve students’ mastery of concept and critical thinking skill. Its procedure was divided into two phases; developmental phase and experimental phase. This developmental research used Four-D Model. However, within this research, the process of development would not involve the last stages, which is disseminate. The teaching learning materials which were developed consist of lesson plan, student handbook, student worksheet, achievement test and critical thinking skill test. The experimental phase employs a research design called one group pretest-posttest design. Results show that the validity of the teaching materials which were developed was good and revealed the enhancement of students’ activities with positive response to the teaching learning process. Furthermore, the learning materials improve the students’ mastery of concept and critical thinking skill.

3D printing technology speeds development.

PubMed

McGowan, James

2013-10-01

James McGowan, R&D product designer for Monodraught, a specialist in 'natural ventilation, natural daylight, and natural cooling systems', discusses the development of Cool-phase, the company's latest innovative application of phase change material (PCM) as a thermal energy store used to actively ventilate and cool buildings. As he explains, when the company decided to re-design an already successful product to further enhance its performance, the use of 3D modelling greatly speeded up prototyping, and helped the design process progress considerably more quickly.

Numerical analysis of nonminimum phase zero for nonuniform link design

NASA Technical Reports Server (NTRS)

Girvin, Douglas L.; Book, Wayne J.

1991-01-01

As the demand for light-weight robots that can operate in a large workspace increases, the structural flexibility of the links becomes more of an issue in control. When the objective is to accurately position the tip while the robot is actuated at the base, the system is nonminimum phase. One important characteristic of nonminimum phase systems is system zeros in the right half of the Laplace plane. The ability to pick the location of these nonminimum phase zeros would give the designer a new freedom similar to pole placement. This research targets a single-link manipulator operating in the horizontal plane and modeled as a Euler-Bernoulli beam with pinned-free end conditions. Using transfer matrix theory, one can consider link designs that have variable cross-sections along the length of the beam. A FORTRAN program was developed to determine the location of poles and zeros given the system model. The program was used to confirm previous research on nonminimum phase systems, and develop a relationship for designing linearly tapered links. The method allows the designer to choose the location of the first pole and zero and then defines the appropriate taper to match the desired locations. With the pole and zero location fixed, the designer can independently change the link's moment of inertia about its axis of rotation by adjusting the height of the beam. These results can be applied to the inverse dynamic algorithms that are currently under development.

Numerical analysis of nonminimum phase zero for nonuniform link design

NASA Astrophysics Data System (ADS)

Girvin, Douglas L.; Book, Wayne J.

1991-11-01

As the demand for light-weight robots that can operate in a large workspace increases, the structural flexibility of the links becomes more of an issue in control. When the objective is to accurately position the tip while the robot is actuated at the base, the system is nonminimum phase. One important characteristic of nonminimum phase systems is system zeros in the right half of the Laplace plane. The ability to pick the location of these nonminimum phase zeros would give the designer a new freedom similar to pole placement. This research targets a single-link manipulator operating in the horizontal plane and modeled as a Euler-Bernoulli beam with pinned-free end conditions. Using transfer matrix theory, one can consider link designs that have variable cross-sections along the length of the beam. A FORTRAN program was developed to determine the location of poles and zeros given the system model. The program was used to confirm previous research on nonminimum phase systems, and develop a relationship for designing linearly tapered links. The method allows the designer to choose the location of the first pole and zero and then defines the appropriate taper to match the desired locations. With the pole and zero location fixed, the designer can independently change the link's moment of inertia about its axis of rotation by adjusting the height of the beam. These results can be applied to the inverse dynamic algorithms that are currently under development.

Meta-analyses and adaptive group sequential designs in the clinical development process.

PubMed

Jennison, Christopher; Turnbull, Bruce W

2005-01-01

The clinical development process can be viewed as a succession of trials, possibly overlapping in calendar time. The design of each trial may be influenced by results from previous studies and other currently proceeding trials, as well as by external information. Results from all of these trials must be considered together in order to assess the efficacy and safety of the proposed new treatment. Meta-analysis techniques provide a formal way of combining the information. We examine how such methods can be used in combining results from: (1) a collection of separate studies, (2) a sequence of studies in an organized development program, and (3) stages within a single study using a (possibly adaptive) group sequential design. We present two examples. The first example concerns the combining of results from a Phase IIb trial using several dose levels or treatment arms with those of the Phase III trial comparing the treatment selected in Phase IIb against a control This enables a "seamless transition" from Phase IIb to Phase III. The second example examines the use of combination tests to analyze data from an adaptive group sequential trial.

The Development of a Gas–Liquid Two-Phase Flow Sensor Applicable to CBM Wellbore Annulus

PubMed Central

Wu, Chuan; Wen, Guojun; Han, Lei; Wu, Xiaoming

2016-01-01

The measurement of wellbore annulus gas–liquid two-phase flow in CBM (coalbed methane) wells is of great significance for reasonably developing gas drainage and extraction processes, estimating CBM output, judging the operating conditions of CBM wells and analyzing stratum conditions. Hence, a specially designed sensor is urgently needed for real-time measurement of gas–liquid two-phase flow in CBM wellbore annulus. Existing flow sensors fail to meet the requirements of the operating conditions of CBM wellbore annulus due to such factors as an inapplicable measurement principle, larger size, poor sealability, high installation accuracy, and higher requirements for fluid media. Therefore, based on the principle of a target flowmeter, this paper designs a new two-phase flow sensor that can identify and automatically calibrate different flow patterns of two-phase flows. Upon the successful development of the new flow sensor, lab and field tests were carried out, and the results show that the newly designed sensor, with a measurement accuracy of ±2.5%, can adapt to the operating conditions of CBM wells and is reliable for long-term work. PMID:27869708

The Development of a Gas-Liquid Two-Phase Flow Sensor Applicable to CBM Wellbore Annulus.

PubMed

Wu, Chuan; Wen, Guojun; Han, Lei; Wu, Xiaoming

2016-11-18

The measurement of wellbore annulus gas-liquid two-phase flow in CBM (coalbed methane) wells is of great significance for reasonably developing gas drainage and extraction processes, estimating CBM output, judging the operating conditions of CBM wells and analyzing stratum conditions. Hence, a specially designed sensor is urgently needed for real-time measurement of gas-liquid two-phase flow in CBM wellbore annulus. Existing flow sensors fail to meet the requirements of the operating conditions of CBM wellbore annulus due to such factors as an inapplicable measurement principle, larger size, poor sealability, high installation accuracy, and higher requirements for fluid media. Therefore, based on the principle of a target flowmeter, this paper designs a new two-phase flow sensor that can identify and automatically calibrate different flow patterns of two-phase flows. Upon the successful development of the new flow sensor, lab and field tests were carried out, and the results show that the newly designed sensor, with a measurement accuracy of ±2.5%, can adapt to the operating conditions of CBM wells and is reliable for long-term work.

Design for effective development and prototyping of the HL-20

NASA Astrophysics Data System (ADS)

Urie, David M.; Floreck, Paul A.; McMorris, John A.; Elvin, John D.

1993-10-01

A feasibility study of the HL-20 personnel launch system (PLS) concept was conducted by a team which focused on creating a PLS design approach and an accelerated development plan consistent with the historical 'Skunk Works' approach to rapid prototyping. Technical design, manufacturing, system testing, and operations and support elements of the predefined baseline concept were evaluated. An initial phase program, featuring a concurrent system test during design and development, leading to the orbital flight of an unmanned HL-20 prototype on a Titan III launch system, was prescribed. A second-phase development and manufacturing plan leading to system operational status was also formulated. Baseline design feature modifications were made when necessary, without compromise to performance, to satisfy the prototype development plan. Technical design details and off-the-shelf hardware candidates were also identified for several subsystems, including the launch-system interface adapter/emergency escape system. The technical feasibility of the system and applicability of the Skunk Works approach to development of the HL-20/PLS were verified.

Space Station Human Factors Research Review. Volume 1: EVA Research and Development

NASA Technical Reports Server (NTRS)

Cohen, Marc M. (Editor); Vykukal, H. C. (Editor)

1988-01-01

An overview is presented of extravehicular activity (EVA) research and development activities at Ames. The majority of the program was devoted to presentations by the three contractors working in parallel on the EVA System Phase A Study, focusing on Implications for Man-Systems Design. Overhead visuals are included for a mission results summary, space station EVA requirements and interface accommodations summary, human productivity study cross-task coordination, and advanced EVAS Phase A study implications for man-systems design. Articles are also included on subsea approach to work systems development and advanced EVA system design requirements.

C-Band Airport Surface Communications System Standards Development. Phase II Final Report. Volume 1: Concepts of Use, Initial System Requirements, Architecture, and AeroMACS Design Considerations

NASA Technical Reports Server (NTRS)

Hall, Edward; Isaacs, James; Henriksen, Steve; Zelkin, Natalie

2011-01-01

This report is provided as part of ITT s NASA Glenn Research Center Aerospace Communication Systems Technical Support (ACSTS) contract NNC05CA85C, Task 7: New ATM Requirements-Future Communications, C-Band and L-Band Communications Standard Development and was based on direction provided by FAA project-level agreements for New ATM Requirements-Future Communications. Task 7 included two subtasks. Subtask 7-1 addressed C-band (5091- to 5150-MHz) airport surface data communications standards development, systems engineering, test bed and prototype development, and tests and demonstrations to establish operational capability for the Aeronautical Mobile Airport Communications System (AeroMACS). Subtask 7-2 focused on systems engineering and development support of the L-band digital aeronautical communications system (L-DACS). Subtask 7-1 consisted of two phases. Phase I included development of AeroMACS concepts of use, requirements, architecture, and initial high-level safety risk assessment. Phase II builds on Phase I results and is presented in two volumes. Volume I (this document) is devoted to concepts of use, system requirements, and architecture, including AeroMACS design considerations. Volume II describes an AeroMACS prototype evaluation and presents final AeroMACS recommendations. This report also describes airport categorization and channelization methodologies. The purposes of the airport categorization task were (1) to facilitate initial AeroMACS architecture designs and enable budgetary projections by creating a set of airport categories based on common airport characteristics and design objectives, and (2) to offer high-level guidance to potential AeroMACS technology and policy development sponsors and service providers. A channelization plan methodology was developed because a common global methodology is needed to assure seamless interoperability among diverse AeroMACS services potentially supplied by multiple service providers.

The Design of Software for Three-Phase Induction Motor Test System

NASA Astrophysics Data System (ADS)

Haixiang, Xu; Fengqi, Wu; Jiai, Xue

2017-11-01

The design and development of control system software is important to three-phase induction motor test equipment, which needs to be completely familiar with the test process and the control procedure of test equipment. In this paper, the software is developed according to the national standard (GB/T1032-2005) about three-phase induction motor test method by VB language. The control system and data analysis software and the implement about motor test system are described individually, which has the advantages of high automation and high accuracy.

Three phase power conversion system for utility interconnected PV applications

NASA Astrophysics Data System (ADS)

Porter, David G.

1999-03-01

Omnion Power Engineering Corporation has developed a new three phase inverter that improves the cost, reliability, and performance of three phase utility interconnected photovoltaic inverters. The inverter uses a new, high manufacturing volume IGBT bridge that has better thermal performance than previous designs. A custom easily manufactured enclosure was designed. Controls were simplified to increase reliability while maintaining important user features.

Consortium for Planning, Developing, and Implementing Exploratory Industrial Career Development Models (Phase I of Three Phases). Interim Report.

ERIC Educational Resources Information Center

Oregon State Univ., Corvallis.

The report describes the organizational phase of a project designed to create program models and supporting literature for exploratory industrial career development programs for grades seven to ten. The project was undertaken by Oregon State University in cooperation with the Oregon State Department of Education and involved the formation of a…

Using Maxwell's Demon to Tame the "Devil in the Details" that are Encountered During System Development

NASA Technical Reports Server (NTRS)

Richardson, David

2018-01-01

Model-Based Systems Engineering (MBSE) is the formalized application of modeling to support system requirements, design, analysis, verification and validation activities beginning in the conceptual design phase and continuing throughout development and later life cycle phases . This presentation will discuss the value proposition that MBSE has for Systems Engineering, and the associated culture change needed to adopt it.

Design and fabrication of a freeform phase plate for high-order ocular aberration correction

NASA Astrophysics Data System (ADS)

Yi, Allen Y.; Raasch, Thomas W.

2005-11-01

In recent years it has become possible to measure and in some instances to correct the high-order aberrations of human eyes. We have investigated the correction of wavefront error of human eyes by using phase plates designed to compensate for that error. The wavefront aberrations of the four eyes of two subjects were experimentally determined, and compensating phase plates were machined with an ultraprecision diamond-turning machine equipped with four independent axes. A slow-tool servo freeform trajectory was developed for the machine tool path. The machined phase-correction plates were measured and compared with the original design values to validate the process. The position of the phase-plate relative to the pupil is discussed. The practical utility of this mode of aberration correction was investigated with visual acuity testing. The results are consistent with the potential benefit of aberration correction but also underscore the critical positioning requirements of this mode of aberration correction. This process is described in detail from optical measurements, through machining process design and development, to final results.

Summary of the Advanced Reactor Design Criteria (ARDC) Phase 2 Activities

DOE Office of Scientific and Technical Information (OSTI.GOV)

Holbrook, Mark Raymond

This report provides an end-of-year summary reflecting the progress and status of proposed regulatory design criteria for advanced non-LWR designs in accordance with the Level 3 milestone in M3AT-15IN2001017 in work package AT-15IN200101. These criteria have been designated as ARDC, and they provide guidance to future applicants for addressing the GDC that are currently applied specifically to LWR designs. The report provides a summary of Phase 2 activities related to the various tasks associated with ARDC development and the subsequent development of example adaptations of ARDC for Sodium Fast Reactor (SFR) and modular High Temperature Gas-cooled Reactor (HTGR) designs.

Phase I of the Near Term Hybrid Passenger Vehicle Development Program. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1980-10-01

The results of Phase I of the Near-Term Hybrid Vehicle Program are summarized. This phase of the program ws a study leading to the preliminary design of a 5-passenger hybrid vehicle utilizing two energy sources (electricity and gasoline/diesel fuel) to minimize petroleum usage on a fleet basis. This report presents the following: overall summary of the Phase I activity; summary of the individual tasks; summary of the hybrid vehicle design; summary of the alternative design options; summary of the computer simulations; summary of the economic analysis; summary of the maintenance and reliability considerations; summary of the design for crash safety;more » and bibliography.« less

A Path to Successful Energy Retrofits: Early Collaboration through Integrated Project Delivery Teams

DOE Office of Scientific and Technical Information (OSTI.GOV)

Parrish, Kristen

2012-10-01

This document guides you through a process for the early design phases of retrofit projects to help you mitigate frustrations commonly experienced by building owners and designers. It outlines the value of forming an integrated project delivery team and developing a communication and information-sharing infrastructure that fosters collaboration. This guide does not present a complete process for designing an energy retrofit for a building. Instead, it focuses on the early design phase tasks related to developing and selecting energy efficiency measures (EEMs) that benefit from collaboration, and highlights the resulting advantages.

Numerical analysis of right-half plane zeros for a single-link manipulator. M.S. Thesis

NASA Technical Reports Server (NTRS)

Girvin, Douglas Lynn

1992-01-01

The purpose of this research is to further develop an understanding of how nonminimum phase zero location is affected by structural link design. As the demand for light-weight robots that can operate in a large workspace increases, the structural flexibility of the links become more of an issue in controls problems. When the objective is to accurately position the tip while the robot is actuated at the base, the system is nonminimum phase. One important characteristic of nonminimum phase systems is system zeros in the right half of the Laplace plane. The ability to pick the location of these nonminimum phase zeros would give the designer a new freedom similar to pole placement. The research targets a single-link manipulator operating in the horizontal plane and modeled as a Euler-Bernoulli beam with pinned-free end conditions. Using transfer matrix theory, one can consider link designs that have variable cross-sections along the length of the beam. A FORTRAN program was developed to determine the location of poles and zeros given the system model. The program was used to confirm previous research on nonminimum phase systems, and develop a relationship for designing linearly tapered links. The method allows the designer to choose the location of the first pole and zero and then defines the appropriate taper to match the desired locations. With the pole and zero location fixes, the designer can independently change the link's moment of inertia about its axis of rotation by adjusting the height of the beam. These results can be applied to inverse dynamic algorithms currently under development at Georgia Tech.

DE-FOA-EE0005502 Advanced Percussive Drilling Technology for Geothermal Exploration and Development Phase II Report.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Su, Jiann-Cherng; Raymond, David W.; Prasad, Somuri V.

Percussive hammers are a promising advance in drilling technology for geothermal since they rely upon rock reduction mechanisms that are well-suited for use in the hard, brittle rock characteristic of geothermal formations. The project research approach and work plan includes a critical path to development of a high-temperature (HT) percussive hammer using a two- phase approach. The work completed in Phase I of the project demonstrated the viability of percussive hammers and that solutions to technical challenges in design, material technology, and performance are likely to be resolved. Work completed in Phase II focused on testing the findings from Phasemore » I and evaluating performance of the materials and designs at high- operating temperatures. A high-operating temperature (HOT) drilling facility was designed, built, and used to test the performance of the DTH under extreme conditions. Results from the testing indicate that a high-temperature capable hammer can be developed and is a viable alternative for user in the driller's toolbox.« less

Tanker avionics and aircrew complement evaluation.

PubMed

Moss, R W; Barbato, G J

1982-11-01

This paper describes an effort to determine control and display criteria for operating SAC's KC-135 tanker with a reduced crew complement. The Tanker Avionics and Aircrew Complement Evaluation (TAACE) Program was a four-phase effort addressing the control and display design issues associated with operating the tanker without the navigator position. Discussed are: the mission analysis phase, during which the tanker's operational responsibilities were defined and documented; the design phase, during which alternative crew station design concepts were developed; the mockup evaluation phase, which accomplished initial SAC crew member assessment of cockpit designs; and the simulation phase, which validated the useability of the crew system redesign. The paper also describes a recommended crew station configuration and discusses some of the philosophy underlying the selection of cockpit hardware and systems.

Innovative vitrification for soil remediation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jetta, N.W.; Patten, J.S.; Hart, J.G.

1995-12-01

The objective of this DOE demonstration program is to validate the performance and operation of the Vortec Cyclone Melting System (CMS{trademark}) for the processing of LLW contaminated soils found at DOE sites. This DOE vitrification demonstration project has successfully progressed through the first two phases. Phase 1 consisted of pilot scale testing with surrogate wastes and the conceptual design of a process plant operating at a generic DOE site. The objective of Phase 2, which is scheduled to be completed the end of FY 95, is to develop a definitive process plant design for the treatment of wastes at amore » specific DOE facility. During Phase 2, a site specific design was developed for the processing of LLW soils and muds containing TSCA organics and RCRA metal contaminants. Phase 3 will consist of a full scale demonstration at the DOE gaseous diffusion plant located in Paducah, KY. Several DOE sites were evaluated for potential application of the technology. Paducah was selected for the demonstration program because of their urgent waste remediation needs as well as their strong management and cost sharing financial support for the project. During Phase 2, the basic nitrification process design was modified to meet the specific needs of the new waste streams available at Paducah. The system design developed for Paducah has significantly enhanced the processing capabilities of the Vortec vitrification process. The overall system design now includes the capability to shred entire drums and drum packs containing mud, concrete, plastics and PCB`s as well as bulk waste materials. This enhanced processing capability will substantially expand the total DOE waste remediation applications of the technology.« less

The Triangle of the Space Launch System Operations

NASA Astrophysics Data System (ADS)

Fayolle, Eric

2010-09-01

Firemen know it as “fire triangle”, mathematicians know it as “golden triangle”, sailormen know it as “Bermuda triangle”, politicians know it as “Weimar triangle”… This article aims to present a new aspect of that shape geometry in the space launch system world: “the triangle of the space launch system operations”. This triangle is composed of these three following topics, which have to be taken into account for any space launch system operation processing: design, safety and operational use. Design performance is of course taking into account since the early preliminary phase of a system development. This design performance is matured all along the development phases, thanks to consecutives iterations in order to respect the financial and timing constraints imposed to the development of the system. This process leads to a detailed and precise design to assess the required performance. Then, the operational use phase brings its batch of constraints during the use of the system. This phase is conducted by specific procedures for each operation. Each procedure has sequences for each sub-system, which have to be conducted in a very precise chronological way. These procedures can be processed by automatic way or manual way, with the necessity or not of the implication of operators, and in a determined environment. Safeguard aims to verify the respect of the specific constraints imposed to guarantee the safety of persons and property, the protection of public health and the environment. Safeguard has to be taken into account above the operational constraints of any space operation, without forgetting the highest safety level for the operators of the space operation, and of course without damaging the facilities or without disturbing the external environment. All space operations are the result of a “win-win” compromise between these three topics. Contrary to the fire triangle where one of the topics has to be suppressed in order to avoid the combustion, no topics at all should be suppressed in the triangle of the space launch system operations. Indeed, if safeguard is not considered since the beginning of the development phase, this development will not take into account safeguard constraints. Then, the operational phase will become very difficult because unavailable, to respect safety rules required for the operational use phase of the system. Taking into account safeguard constraints in late project phases will conduct to very high operational constraints, sometimes quite disturbing for the operator, even blocking to be able to consider the operational use phase as mature and optimized. On the contrary, if design performance is not taken into account in order to favor safeguard aspect in the operational use phase, system design will not be optimized, what will lead to high planning and timing impacts. The examples detailed in this article show the compromise for what each designer should confront with during the development of any system dealing with the safety of persons and property, the protection of public health and the environment.

Status of the Flooding Fragility Testing Development

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pope, C. L.; Savage, B.; Bhandari, B.

2016-06-01

This report provides an update on research addressing nuclear power plant component reliability under flooding conditions. The research includes use of the Component Flooding Evaluation Laboratory (CFEL) where individual components and component subassemblies will be tested to failure under various flooding conditions. The resulting component reliability data can then be incorporated with risk simulation strategies to provide a more thorough representation of overall plant risk. The CFEL development strategy consists of four interleaved phases. Phase 1 addresses design and application of CFEL with water rise and water spray capabilities allowing testing of passive and active components including fully electrified components.more » Phase 2 addresses research into wave generation techniques followed by the design and addition of the wave generation capability to CFEL. Phase 3 addresses methodology development activities including small scale component testing, development of full scale component testing protocol, and simulation techniques including Smoothed Particle Hydrodynamic (SPH) based computer codes. Phase 4 involves full scale component testing including work on full scale component testing in a surrogate CFEL testing apparatus.« less

Developing and Applying Synthesis Models of Emerging Space Systems

DTIC Science & Technology

2016-03-01

enables the exploration of small satellite physical trade -offs early in the conceptual design phase of the DOD space acquisition process. Early...provide trade space insights that can assist DOD space acquisition professionals in making better decisions in the conceptual design phase. More informed

Developing Online Problem-Based Resources for the Professional Development of Teachers of Children with Visual Impairment

ERIC Educational Resources Information Center

McLinden, Mike; McCall, Steve; Hinton, Danielle; Weston, Annette; Douglas, Graeme

2006-01-01

This article presents a summary of the results from phase 1 of a two-phase research project. Drawing on the principles of problem-based learning (PBL), the aims of phase 1 were to design, develop and evaluate a set of flexible online teaching resources for use within a virtual learning environment. Participants in the project (n = 10) were…

Microwave scanning beam approach and landing system phased array antenna.

DOT National Transportation Integrated Search

1971-09-01

The design, operating instructions, detailed logic circuitry, and antenna test range results for the electronic circular scanning phased array developed at TSC (DOTSCAN) are described. Components developed for this effort are also described, and test...

Full-Scale Spacecraft Simulator Design for a 2D Zero Gravity Small Body Surface Sampling Validation

NASA Astrophysics Data System (ADS)

Mongelli, Marco

NASA is developing several Touch-And-Go (TAG) classes of missions. These types of missions like the OSIRIS-REx asteroid sample return [1] or a comet sample return mission (CSSR)[2], consist usually in three phases: propulsive approach to the target, sampling and propulsion to move the spacecraft away from the target. The development of TAG mission, from concept to realization, is usually divided in two phases: Phase I discusses the major trades that could affect the mission architecture; Phase II focuses in detail on the design. This project of a spacecraft emulator fits into phase II and specifically on the way the spacecraft could react in absence of gravity while the Sample Acquisition System (SAS) is collecting the sample. A full-scale spacecraft on a 2D zero-friction environment has been designed. Also a propulsion system has been implemented to re-create the full dynamics of a spacecraft in space.

Controlled-Root Approach To Digital Phase-Locked Loops

NASA Technical Reports Server (NTRS)

Stephens, Scott A.; Thomas, J. Brooks

1995-01-01

Performance tailored more flexibly and directly to satisfy design requirements. Controlled-root approach improved method for analysis and design of digital phase-locked loops (DPLLs). Developed rigorously from first principles for fully digital loops, making DPLL theory and design simpler and more straightforward (particularly for third- or fourth-order DPLL) and controlling performance more accurately in case of high gain.

Mars Rover/Sample Return - Phase A cost estimation

NASA Technical Reports Server (NTRS)

Stancati, Michael L.; Spadoni, Daniel J.

1990-01-01

This paper presents a preliminary cost estimate for the design and development of the Mars Rover/Sample Return (MRSR) mission. The estimate was generated using a modeling tool specifically built to provide useful cost estimates from design parameters of the type and fidelity usually available during early phases of mission design. The model approach and its application to MRSR are described.

Laboratory performance evaluation of CIR-emulsion and its comparison against CIR-foam test results from phase III.

DOT National Transportation Integrated Search

2009-12-01

Currently, no standard mix design procedure is available for CIR-emulsion in Iowa. The CIR-foam mix : design process developed during the previous phase is applied for CIR-emulsion mixtures with varying : emulsified asphalt contents. Dynamic modulus ...

UWR/MSAA demonstration of coordinated human-services transportation models - phase II : phased implementation.

DOT National Transportation Integrated Search

2012-12-01

This report presents the results of a 16-month project for system development and design of a model for a Travel Management Coordination Center (TMCC) using ITS capabilities. The system was designed as a tool to facilitate the exchange of knowledge a...

A Human-Centered Design Methodology to Enhance the Usability, Human Factors, and User Experience of Connected Health Systems: A Three-Phase Methodology.

PubMed

Harte, Richard; Glynn, Liam; Rodríguez-Molinero, Alejandro; Baker, Paul Ma; Scharf, Thomas; Quinlan, Leo R; ÓLaighin, Gearóid

2017-03-16

Design processes such as human-centered design, which involve the end user throughout the product development and testing process, can be crucial in ensuring that the product meets the needs and capabilities of the user, particularly in terms of safety and user experience. The structured and iterative nature of human-centered design can often present a challenge when design teams are faced with the necessary, rapid, product development life cycles associated with the competitive connected health industry. We wanted to derive a structured methodology that followed the principles of human-centered design that would allow designers and developers to ensure that the needs of the user are taken into account throughout the design process, while maintaining a rapid pace of development. In this paper, we present the methodology and its rationale before outlining how it was applied to assess and enhance the usability, human factors, and user experience of a connected health system known as the Wireless Insole for Independent and Safe Elderly Living (WIISEL) system, a system designed to continuously assess fall risk by measuring gait and balance parameters associated with fall risk. We derived a three-phase methodology. In Phase 1 we emphasized the construction of a use case document. This document can be used to detail the context of use of the system by utilizing storyboarding, paper prototypes, and mock-ups in conjunction with user interviews to gather insightful user feedback on different proposed concepts. In Phase 2 we emphasized the use of expert usability inspections such as heuristic evaluations and cognitive walkthroughs with small multidisciplinary groups to review the prototypes born out of the Phase 1 feedback. Finally, in Phase 3 we emphasized classical user testing with target end users, using various metrics to measure the user experience and improve the final prototypes. We report a successful implementation of the methodology for the design and development of a system for detecting and predicting falls in older adults. We describe in detail what testing and evaluation activities we carried out to effectively test the system and overcome usability and human factors problems. We feel this methodology can be applied to a wide variety of connected health devices and systems. We consider this a methodology that can be scaled to different-sized projects accordingly. ©Richard Harte, Liam Glynn, Alejandro Rodríguez-Molinero, Paul MA Baker, Thomas Scharf, Leo R Quinlan, Gearóid ÓLaighin. Originally published in JMIR Human Factors (http://humanfactors.jmir.org), 16.03.2017.

User systems guidelines for software projects

DOE Office of Scientific and Technical Information (OSTI.GOV)

Abrahamson, L.

1986-04-01

This manual presents guidelines for software standards which were developed so that software project-development teams and management involved in approving the software could have a generalized view of all phases in the software production procedure and the steps involved in completing each phase. Guidelines are presented for six phases of software development: project definition, building a user interface, designing software, writing code, testing code, and preparing software documentation. The discussions for each phase include examples illustrating the recommended guidelines. 45 refs. (DWL)

LST phase A design update study

NASA Technical Reports Server (NTRS)

1973-01-01

An update is presented of the Phase A study of the Large Space Telescope (LST), based on changes in guidelines and new data developed subsequent to the Phase A study. The study defines an LST concept based on the broad mission guidelines provided by the Office of Space Science (OSS), the scientific requirements developed by OSS with the scientific community, and an understanding of long range NASA planning current at the time the study was performed. A low cost design approach was followed. This resulted in the use of standard spacecraft hardware, the provision for maintenance at the black box level, growth potential in systems designs, and sharing of shuttle maintenance flights with other payloads (See N73-18449 through N73-18453)

Material Development to Raise Awareness of Using Smart Boards: An Example Design and Development Research

ERIC Educational Resources Information Center

Günaydin, Serpil; Karamete, Aysen

2016-01-01

This study aims to develop training material that will help raise awareness in prospective teachers regarding the benefits of using smart boards in the classroom. In this study, a Type 2 design and development research method (DDR) was used. The material was developed by applying phases of ADDIE--an instructional systems design model. The…

Understanding Preferences for Osteoporosis Information to Develop an Osteoporosis Patient Education Brochure

PubMed Central

Edmonds, Stephanie W; Solimeo, Samantha L; Nguyen, Vu-Thuy; Wright, Nicole C; Roblin, Douglas W; Saag, Kenneth G; Cram, Peter

2017-01-01

Context Patient education materials can provide important information related to osteoporosis prevention and treatment. However, available osteoporosis education materials fail to follow best-practice guidelines for patient education. Objective To develop an educational brochure on bone health for adults aged 50 years and older using mixed-method, semistructured interviews. Design This project consisted of 3 phases. In Phase 1, we developed written content that included information about osteoporosis. Additionally, we designed 2 graphic-rich brochures, Brochure A (photographs) and Brochure B (illustrations). In Phase 2, interviewers presented the text-only document and both brochure designs to 53 participants from an academic Medical Center in the Midwest and an outpatient clinic in the Southeastern region of the US. Interviewers used open- and closed-ended questions to elicit opinions regarding the brochures. In Phase 3, using feedback from Phase 2, we revised the brochure and presented it to 11 participants at a third site in the Southeastern US. Main Outcome Measures Participants’ comprehension of brochure text and acceptability of brochure design. Results We enrolled 64 participants. Most were women, white, and college-educated, with an average age of 66.1 years. Participants were able to restate the basic content of the brochure and preferred Brochure A’s use of photographs. Conclusions Using feedback from older adults, we developed and refined a brochure for communicating bone health information to older adults at risk of osteoporosis and fragility fractures. The methods outlined in this article may serve to guide others in developing health educational brochures for chronic medical conditions. PMID:28080957

Design, analysis, and testing of the Phase 1 CSI Evolutionary Model erectable truss

NASA Technical Reports Server (NTRS)

Gronet, M. J.; Davis, D. A.; Kintis, D. H.; Brillhart, R. D.; Atkins, E. M.

1992-01-01

This report addressed the design, analysis, and testing of the erectable truss structure for the Phase 1 CSI Evolutionary Model (CEM) testbed. The Phase 1 CEM testbed is the second testbed to form part of an ongoing program of focused research at NASA/LaRC in the development of Controls-Structures Integration (CSI) technology. The Phase 1 CEM contains the same overall geometry, weight, and sensor locations as the Phase 0 CEM, but is based in an integrated controller and structure design, whereby both structure and controller design variables are sized simultaneously. The Phase 1 CEM design features seven truss sections composed of struts with tailored mass and stiffness properties. A common erectable joint is used and the strut stiffness is tailored by varying the cross-sectional area. To characterize the structure, static tests were conducted on individual struts and 10-bay truss assemblies. Dynamic tests were conducted on 10-bay truss assemblies as well as the fully-assembled CEM truss. The results indicate that the static and dynamic properties of the structure are predictable, well-characterized, and within the performance requirements established during the Phase 1 CEM integrated controller/structure design analysis.

Alkaline static feed electrolyzer based oxygen generation system

NASA Technical Reports Server (NTRS)

Noble, L. D.; Kovach, A. J.; Fortunato, F. A.; Schubert, F. H.; Grigger, D. J.

1988-01-01

In preparation for the future deployment of the Space Station, an R and D program was established to demonstrate integrated operation of an alkaline Water Electrolysis System and a fuel cell as an energy storage device. The program's scope was revised when the Space Station Control Board changed the energy storage baseline for the Space Station. The new scope was aimed at the development of an alkaline Static Feed Electrolyzer for use in an Environmental Control/Life Support System as an oxygen generation system. As a result, the program was divided into two phases. The phase 1 effort was directed at the development of the Static Feed Electrolyzer for application in a Regenerative Fuel Cell System. During this phase, the program emphasized incorporation of the Regenerative Fuel Cell System design requirements into the Static Feed Electrolyzer electrochemical module design and the mechanical components design. The mechanical components included a Pressure Control Assembly, a Water Supply Assembly and a Thermal Control Assembly. These designs were completed through manufacturing drawing during Phase 1. The Phase 2 effort was directed at advancing the Alkaline Static Feed Electrolyzer database for an oxygen generation system. This development was aimed at extending the Static Feed Electrolyzer database in areas which may be encountered from initial fabrication through transportation, storage, launch and eventual Space Station startup. During this Phase, the Program emphasized three major areas: materials evaluation, electrochemical module scaling and performance repeatability and Static Feed Electrolyzer operational definition and characterization.

Designing an activity-based costing model for a non-admitted prisoner healthcare setting.

PubMed

Cai, Xiao; Moore, Elizabeth; McNamara, Martin

2013-09-01

To design and deliver an activity-based costing model within a non-admitted prisoner healthcare setting. Key phases from the NSW Health clinical redesign methodology were utilised: diagnostic, solution design and implementation. The diagnostic phase utilised a range of strategies to identify issues requiring attention in the development of the costing model. The solution design phase conceptualised distinct 'building blocks' of activity and cost based on the speciality of clinicians providing care. These building blocks enabled the classification of activity and comparisons of costs between similar facilities. The implementation phase validated the model. The project generated an activity-based costing model based on actual activity performed, gained acceptability among clinicians and managers, and provided the basis for ongoing efficiency and benchmarking efforts.

Software reuse issues affecting AdaNET

NASA Technical Reports Server (NTRS)

Mcbride, John G.

1989-01-01

The AdaNet program is reviewing its long-term goals and strategies. A significant concern is whether current AdaNet plans adequately address the major strategic issues of software reuse technology. The major reuse issues of providing AdaNet services that should be addressed as part of future AdaNet development are identified and reviewed. Before significant development proceeds, a plan should be developed to resolve the aforementioned issues. This plan should also specify a detailed approach to develop AdaNet. A three phased strategy is recommended. The first phase would consist of requirements analysis and produce an AdaNet system requirements specification. It would consider the requirements of AdaNet in terms of mission needs, commercial realities, and administrative policies affecting development, and the experience of AdaNet and other projects promoting the transfer software engineering technology. Specifically, requirements analysis would be performed to better understand the requirements for AdaNet functions. The second phase would provide a detailed design of the system. The AdaNet should be designed with emphasis on the use of existing technology readily available to the AdaNet program. A number of reuse products are available upon which AdaNet could be based. This would significantly reduce the risk and cost of providing an AdaNet system. Once a design was developed, implementation would proceed in the third phase.

6-D, A Process Framework for the Design and Development of Web-based Systems.

ERIC Educational Resources Information Center

Christian, Phillip

2001-01-01

Explores how the 6-D framework can form the core of a comprehensive systemic strategy and help provide a supporting structure for more robust design and development while allowing organizations to support whatever methods and models best suit their purpose. 6-D stands for the phases of Web design and development: Discovery, Definition, Design,…

PROFIL: A Method for the Development of Multimedia.

ERIC Educational Resources Information Center

Koper, Rob

1995-01-01

Describes a dedicated method for the design of multimedia courseware, called PROFIL, which integrates instructional design with software engineering techniques and incorporates media selection in the design methodology. The phases of development are outlined: preliminary investigation, definition, script, technical realization, implementation, and…

Application and Design Characteristics of Generalized Training Devices.

ERIC Educational Resources Information Center

Parker, Edward L.

This program identified applications and developed design characteristics for generalized training devices. The first of three sequential phases reviewed in detail new developments in Naval equipment technology that influence the design of maintenance training devices: solid-state circuitry, modularization, digital technology, standardization,…

Testing vision with angular and radial multifocal designs using Adaptive Optics.

PubMed

Vinas, Maria; Dorronsoro, Carlos; Gonzalez, Veronica; Cortes, Daniel; Radhakrishnan, Aiswaryah; Marcos, Susana

2017-03-01

Multifocal vision corrections are increasingly used solutions for presbyopia. In the current study we have evaluated, optically and psychophysically, the quality provided by multizone radial and angular segmented phase designs. Optical and relative visual quality were evaluated using 8 subjects, testing 6 phase designs. Optical quality was evaluated by means of Visual Strehl-based-metrics (VS). The relative visual quality across designs was obtained through a psychophysical paradigm in which images viewed through 210 pairs of phase patterns were perceptually judged. A custom-developed Adaptive Optics (AO) system, including a Hartmann-Shack sensor and an electromagnetic deformable mirror, to measure and correct the eye's aberrations, and a phase-only reflective Spatial Light Modulator, to simulate the phase designs, was developed for this study. The multizone segmented phase designs had 2-4 zones of progressive power (0 to +3D) in either radial or angular distributions. The response of an "ideal observer" purely responding on optical grounds to the same psychophysical test performed on subjects was calculated from the VS curves, and compared with the relative visual quality results. Optical and psychophysical pattern-comparison tests showed that while 2-zone segmented designs (angular & radial) provided better performance for far and near vision, 3- and 4-zone segmented angular designs performed better for intermediate vision. AO-correction of natural aberrations of the subjects modified the response for the different subjects but general trends remained. The differences in perceived quality across the different multifocal patterns are, in a large extent, explained by optical factors. AO is an excellent tool to simulate multifocal refractions before they are manufactured or delivered to the patient, and to assess the effects of the native optics to their performance. Copyright © 2016 Elsevier Ltd. All rights reserved.

Space Fence PDR Concept Development Phase

NASA Astrophysics Data System (ADS)

Haines, L.; Phu, P.

2011-09-01

The Space Fence, a major Air Force acquisition program, will become the dominant low-earth orbit uncued sensor in the space surveillance network (SSN). Its primary objective is to provide a 24/7 un-cued capability to find, fix, and track small objects in low earth orbit to include emerging and evolving threats, as well as the rapidly growing population of orbital debris. Composed of up to two geographically dispersed large-scale S-band phased array radars, this new system-of-systems concept will provide comprehensive Space Situational Awareness through net-centric operations and integrated decision support. Additionally, this program will facilitate cost saving force structure changes in the SSN, specifically including the decommissioning of very-high frequency VHF Air Force Space Surveillance System (AFSSS). The Space Fence Program Office entered a Preliminary Design Review (PDR) concept development phase in January 2011 to achieve the delivery of the Initial Operational Capability (IOC) expected in FY17. Two contractors were awarded to perform preliminary system design, conduct radar performance analyses and evaluations, and develop a functional PDR radar system prototype. The key objectives for the Phase A PDR effort are to reduce Space Fence total program technical, cost, schedule, and performance risk. The overall program objective is to achieve a preliminary design that demonstrates sufficient technical and manufacturing maturity and that represents a low risk, affordable approach to meet the Space Fence Technical Requirements Document (TRD) requirements for the final development and production phase to begin in 3QFY12. This paper provides an overview of the revised Space Fence program acquisition strategy for the Phase-A PDR phase to IOC, the overall program milestones and major technical efforts. In addition, the key system trade studies and modeling/simulation efforts undertaken during the System Design Requirement (SDR) phase to address and mitigate technical challenges of the Space Fence System will also be discussed. Examples include radar system optimization studies, modeling and simulation for system performance assessment, investigation of innovative Astrodynamics algorithms for initial orbit determination and observation correlation.

Approach to developing reliable space reactor power systems

NASA Technical Reports Server (NTRS)

Mondt, Jack F.; Shinbrot, Charles H.

1991-01-01

During Phase II, the Engineering Development Phase, the SP-100 Project has defined and is pursuing a new approach to developing reliable power systems. The approach to developing such a system during the early technology phase is described along with some preliminary examples to help explain the approach. Developing reliable components to meet space reactor power system requirements is based on a top-down systems approach which includes a point design based on a detailed technical specification of a 100-kW power system. The SP-100 system requirements implicitly recognize the challenge of achieving a high system reliability for a ten-year lifetime, while at the same time using technologies that require very significant development efforts. A low-cost method for assessing reliability, based on an understanding of fundamental failure mechanisms and design margins for specific failure mechanisms, is being developed as part of the SP-100 Program.

Preliminary Design Phases, Part of Indoor Air Quality Design Tools for Schools

EPA Pesticide Factsheets

The typical design process for schools begins with programming and selection of the architectural-engineering team. It then proceeds through schematic design, design development, contract documents, construction, commissioning and occupancy.

Flexible design in water and wastewater engineering--definitions, literature and decision guide.

PubMed

Spiller, Marc; Vreeburg, Jan H G; Leusbrock, Ingo; Zeeman, Grietje

2015-02-01

Urban water and wastewater systems face uncertain developments including technological progress, climate change and urban development. To ensure the sustainability of these systems under dynamic conditions it has been proposed that technologies and infrastructure should be flexible, adaptive and robust. However, in literature it is often unclear what these technologies and infrastructure are. Furthermore, the terms flexible, adaptive and robust are often used interchangeably, despite important differences. In this paper we will i) define the terminology, ii) provide an overview of the status of flexible infrastructure design alternatives for water and wastewater networks and treatment, and iii) develop guidelines for the selection of flexible design alternatives. Results indicate that, with the exception of Net Present Valuation methods, there is little research available on the design and evaluation of technologies that can enable flexibility. Flexible design alternatives reviewed include robust design, phased design, modular design, modular/component platform design and design for remanufacturing. As developments in the water sector are driven by slow variables (climate change, urban development), rather than market forces, it is suggested that phased design or component platform designs are suitable for responding to change, while robust design is an option when operations face highly dynamic variability. Copyright © 2014 Elsevier Ltd. All rights reserved.

Investigation into the development of computer aided design software for space based sensors

NASA Technical Reports Server (NTRS)

Pender, C. W.; Clark, W. L.

1987-01-01

The described effort is phase one of the development of a Computer Aided Design (CAD) software to be used to perform radiometric sensor design. The software package will be referred to as SCAD and is directed toward the preliminary phase of the design of space based sensor system. The approach being followed is to develop a modern, graphic intensive, user friendly software package using existing software as building blocks. The emphasis will be directed toward the development of a shell containing menus, smart defaults, and interfaces, which can accommodate a wide variety of existing application software packages. The shell will offer expected utilities such as graphics, tailored menus, and a variety of drivers for I/O devices. Following the development of the shell, the development of SCAD is planned as chiefly selection and integration of appropriate building blocks. The phase one development activities have included: the selection of hardware which will be used with SCAD; the determination of the scope of SCAD; the preliminary evaluation of a number of software packages for applicability to SCAD; determination of a method for achieving required capabilities where voids exist; and then establishing a strategy for binding the software modules into an easy to use tool kit.

Enhanced human service transportation models : joint demonstration. Phase 1, System planning and design process evaluation : baseline analysis

DOT National Transportation Integrated Search

2007-11-13

This document presents the findings from the baseline phase of the evaluation of the process being used by eight sites to develop a design for a Travel Management Coordination Center (TMCC) for improved coordination of human service transportation wi...

A System Analysis Approach to Robot Gripper Control Using Phase Lag Compensator Bode Designs

NASA Astrophysics Data System (ADS)

Aye, Khin Muyar; Lin, Htin; Tun, Hla Myo

2008-10-01

In this paper, we introduce the result comparisons that were developed for the phase lag compensator design using Bode Plots. The implementation of classical experiments as MATLAB m-files is described. Robot gripper control system can be designed to gain insight into a variety of concepts, including stabilization of unstable systems, compensation properties, Bode analysis and design. The analysis has resulted in a number of important conclusions for the design of a new generation of control support systems.

Design, Development and Validation of the Eurostar 3000 Large Propellant Tank

NASA Astrophysics Data System (ADS)

Autric, J.-M.; Catherall, D.; Figues, C.; Brockhoff, T.; Lafranconi, R.

2004-10-01

EADS Astrium has undertaken the design and development of an enlarged propellant tank for its high modular Eurostar 3000 telecom satellites platform. The design and development activities included fracture, stress and functional analysis, the manufacturing of development models for the propellant management device, the qualification of new manufacturing processes and the optimization of the design with respect to the main requirements. The successful design and development-testing phase has allowed starting the manufacturing of the qualification model.

Job Aid Manuals for Phase III--DEVELOP of the Instructional Systems Development Model.

ERIC Educational Resources Information Center

Schulz, Russel E.; Farrell, Jean R.

Designed to supplement the descriptive authoring flowcharts presented in a companion volume, this manual includes specific guidance, examples, and other information referred to in the flowcharts for the implementation of the third phase of the Instructional Systems Development Model (ISD). The introductory section includes definitions;…

Space station definitions, design, and development. Task 5: Multiple arm telerobot coordination and control: Manipulator design methodology

NASA Technical Reports Server (NTRS)

Stoughton, R. M.

1990-01-01

A proposed methodology applicable to the design of manipulator systems is described. The current design process is especially weak in the preliminary design phase, since there is no accepted measure to be used in trading off different options available for the various subsystems. The design process described uses Cartesian End-Effector Impedance as a measure of performance for the system. Having this measure of performance, it is shown how it may be used to determine the trade-offs necessary to the preliminary design phase. The design process involves three main parts: (1) determination of desired system performance in terms of End-Effector Impedance; (2) trade-off design options to achieve this desired performance; and (3) verification of system performance through laboratory testing. The design process is developed using numerous examples and experiments to demonstrate the feasability of this approach to manipulator design.

25 CFR 900.131 - What role does the Secretary play during the performance of a self-determination construction...

Code of Federal Regulations, 2011 CFR

2011-04-01

... phase activities. The Secretary shall provide the Indian tribe or tribal organization with an opportunity to review the project construction documents at the concept phase, the schematic phase, the design development phase, and the final construction documents phase, or as otherwise negotiated. Upon receipt of...

Design, Development, Testing, and Evaluation: Human Factors Engineering

NASA Technical Reports Server (NTRS)

Adelstein, Bernard; Hobbs, Alan; OHara, John; Null, Cynthia

2006-01-01

While human-system interaction occurs in all phases of system development and operation, this chapter on Human Factors in the DDT&E for Reliable Spacecraft Systems is restricted to the elements that involve "direct contact" with spacecraft systems. Such interactions will encompass all phases of human activity during the design, fabrication, testing, operation, and maintenance phases of the spacecraft lifespan. This section will therefore consider practices that would accommodate and promote effective, safe, reliable, and robust human interaction with spacecraft systems. By restricting this chapter to what the team terms "direct contact" with the spacecraft, "remote" factors not directly involved in the development and operation of the vehicle, such as management and organizational issues, have been purposely excluded. However, the design of vehicle elements that enable and promote ground control activities such as monitoring, feedback, correction and reversal (override) of on-board human and automation process are considered as per NPR8705.2A, Section 3.3.

Performance of WPA Conductivity Sensor during Two-Phase Fluid Flow in Microgravity

NASA Technical Reports Server (NTRS)

Carter, Layne; O'Connor, Edward W.; Snowdon, Doug

2003-01-01

The Conductivity Sensor designed for use in the Node 3 Water Processor Assembly (WPA) was based on the existing Space Shuttle application for the fuel cell water system. However, engineering analysis has determined that this sensor design is potentially sensitive to two-phase fluid flow (gadliquid) in microgravity. The source for this sensitivity is the fact that gas bubbles will become lodged between the sensor probe and the wall of the housing without the aid of buoyancy in l-g. Once gas becomes lodged in the housing, the measured conductivity will be offset based on the volume of occluded gas. A development conductivity sensor was flown on the NASA Microgravity Plan to measure the offset, which was determined to range between 0 and 50%. Based on these findings, a development program was initiated at the sensor s manufacturer to develop a sensor design fully compatible with two-phase fluid flow in microgravity.

MSFC Sortie Laboratory Environmental Control System (ECS) phase B design study results

NASA Technical Reports Server (NTRS)

Ignatonis, A. J.; Mitchell, K. L.

1974-01-01

Phase B effort of the Sortie Lab program has concluded. Results of that effort are presented which pertain to the definitions of the environmental control system (ECS). Numerous design studies were performed in Phase B to investigate system feasibility, complexity, weight, and cost. The results and methods employed for these design studies are included. An autonomous Sortie Lab ECS was developed which utilizes a deployed space radiator. Total system weight was projected to be 1814.4 kg including the radiator and fluids. ECS power requirements were estimated at 950 watts.

Design & Technology Teaching: A Journal of New Approaches, 1994-95.

ERIC Educational Resources Information Center

Design and Technology Teaching, 1995

1995-01-01

This document consists of the three issues of the journal "Design & Technology Teaching" for the 1994-95 publishing year. This journal focuses on developments in design and technology across all phases of education. It provides a forum for sharing and developing expertise in all the contributing areas of design and technology: art and design,…

Space station wardroom habitability and equipment study

NASA Technical Reports Server (NTRS)

Nixon, David; Miller, Christopher; Fauquet, Regis

1989-01-01

Experimental designs in life-size mock-up form for the wardroom facility for the Space Station Habitability Module are explored and developed. In Phase 1, three preliminary concepts for the wardroom configuration are fabricated and evaluated. In Phase 2, the results of Phase 1 are combined with a specific range of program design requirements to provide the design criteria for the fabrication of an innovative medium-fidelity mock-up of a wardrobe configuration. The study also focuses on the design and preliminary prototyping of selected equipment items including crew exercise compartments, a meal/meeting table and a portable workstation. Design criteria and requirements are discussed and documented. Preliminary and final mock-ups and equipment prototypes are described and illustrated.

Designing a model for trauma system management using public health approach: the case of Iran.

PubMed

Tarighi, Payam; Tabibi, Seyed Jamaledin; Motevalian, Seyed Abbas; Tofighi, Shahram; Maleki, Mohammad Reza; Delgoshaei, Bahram; Panahi, Farzad; Masoomi, Gholam Reza

2012-01-01

Trauma is a leading cause of death and disability around the world. Injuries are responsible for about six million deaths annually, of which ninety percent occur in developing countries. In Iran, injuries are the most common cause of death among age groups below fifty. Trauma system development is a systematic and comprehensive approach to injury prevention and treatment whose effectiveness has been proved. The present study aims at designing a trauma system management model as the first step toward trauma system establishment in Iran. In this qualitative research, a conceptual framework was developed based on the public health approach and three well-known trauma system models. We used Benchmarks, Indicators and Scoring (BIS) to analyze the current situation of Iran trauma care system. Then the trauma system management was designed using the policy development phase of public health approach The trauma system management model, validated by a panel of experts, describes lead agency, trauma system plan, policy-making councils, and data-based control according to the four main functions of management: leading, planning, organizing and controlling. This model may be implemented in two phases: the exclusive phase, focusing on resource integration and the inclusive phase, which concentrates on system development. The model could facilitate the development of trauma system in Iran through pilot studies as the assurance phase of public health approach. Furthermore, the model can provide a practical framework for trauma system management at the international level.

Design, fabrication, testing and delivery of a solar collector

NASA Technical Reports Server (NTRS)

Sims, W. H.; Ballheim, R. W.; Bartley, S. M.; Smith, G. W.

1976-01-01

A two phase program encompassing the redesign and fabrication of a solar collector which is low in cost and aesthetically appealing is described. Phase one work reviewed the current collector design and developed a low-cost design based on specific design/performance/cost requirements. Throughout this phase selected collector component materials were evaluated by testing and by considering cost, installation, maintainability and durability. The resultant collector design was composed of an absorber plate, insulation, frame, cover, desiccant and sealant. In Phase two, three collector prototypes were fabricated and evaluated for both nonthermal and thermal characteristics. Tests included static load tests of covers, burst pressure tests of absorber plates, and tests for optical characteristics of selective absorber plate coatings. The three prototype collectors were shipped to Marshall Space Flight Center for use in their solar heating and cooling test facility.

Design of Training Systems, Phase II Report, Volume III; Model Program Descriptions and Operating Procedures. TAEG Report No. 12-2.

ERIC Educational Resources Information Center

Naval Training Equipment Center, Orlando, FL. Training Analysis and Evaluation Group.

The Design of Training Systems (DOTS) project was initiated by the Department of Defense (DOD) to develop tools for the effective management of military training organizations. Volume 3 contains the model and data base program descriptions and operating procedures designed for phase 2 of the project. Flow charts and program listings for the…

Evaluation of Current Practice for Illumination at Roundabouts : Safety and Illumination of Roundabouts (Phase I)

DOT National Transportation Integrated Search

2016-03-01

This report is for the first phase of a two-phase research program to develop recommended practices for GDOT for lighting rural roundabouts. Phase I of the study was designed to improve our understanding of the relationship between roundabout illumin...

The Design of Phase II Clinical Trials Testing Cancer Therapeutics: Consensus Recommendations from the Clinical Trial Design Task Force of the National Cancer Institute Investigational Drug Steering Committee

PubMed Central

Seymour, Lesley; Ivy, S. Percy; Sargent, Daniel; Spriggs, David; Baker, Laurence; Rubinstein, Larry; Ratain, Mark J; Le Blanc, Michael; Stewart, David; Crowley, John; Groshen, Susan; Humphrey, Jeffrey S; West, Pamela; Berry, Donald

2010-01-01

The optimal design of phase II studies continues to be the subject of vigorous debate, especially with regards to studies of newer molecularly targeted agents. The observations that many new therapeutics ‘fail’ in definitive phase III studies, coupled with the numbers of new agents to be tested as well as the increasing costs and complexity of clinical trials further emphasizes the critical importance of robust and efficient phase II design. The Clinical Trial Design Task Force(CTD-TF)of the NCI Investigational Drug Steering Committee (IDSC) has published a series of discussion papers on Phase II trial design in Clinical Cancer Research. The IDSC has developed formal recommendations regarding aspects of phase II trial design which are the subject of frequent debate such as endpoints(response vs. progression free survival), randomization(single arm designs vs. randomization), inclusion of biomarkers, biomarker based patient enrichment strategies, and statistical design(e.g. two stage designs vs. multiple-group adaptive designs). While these recommendations in general encourage the use of progression-free survival as the primary endpoint, the use of randomization, the inclusion of biomarkers and the incorporation of newer designs, we acknowledge that objective response as an endpoint, and single arm designs, remain relevant in certain situations. The design of any clinical trial should always be carefully evaluated and justified based on the characteristic specific to the situation. PMID:20215557

Implementation of adiabatic geometric gates with superconducting phase qubits.

PubMed

Peng, Z H; Chu, H F; Wang, Z D; Zheng, D N

2009-01-28

We present an adiabatic geometric quantum computation strategy based on the non-degenerate energy eigenstates in (but not limited to) superconducting phase qubit systems. The fidelity of the designed quantum gate was evaluated in the presence of simulated thermal fluctuations in a superconducting phase qubits circuit and was found to be quite robust against random errors. In addition, it was elucidated that the Berry phase in the designed adiabatic evolution may be detected directly via the quantum state tomography developed for superconducting qubits. We also analyze the effects of control parameter fluctuations on the experimental detection of the Berry phase.

Multiphase Flow Technology Impacts on Thermal Control Systems for Exploration

NASA Technical Reports Server (NTRS)

McQuillen, John; Sankovic, John; Lekan, Jack

2006-01-01

The Two-Phase Flow Facility (TPHIFFy) Project focused on bridging the critical knowledge gap by developing and demonstrating critical multiphase fluid products for advanced life support, thermal management and power conversion systems that are required to enable the Vision for Space Exploration. Safety and reliability of future systems will be enhanced by addressing critical microgravity fluid physics issues associated with flow boiling, condensation, phase separation, and system stability. The project included concept development, normal gravity testing, and reduced gravity aircraft flight campaigns, in preparation for the development of a space flight experiment implementation. Data will be utilized to develop predictive models that could be used for system design and operation. A single fluid, two-phase closed thermodynamic loop test bed was designed, assembled and tested. The major components in this test bed include: a boiler, a condenser, a phase separator and a circulating pump. The test loop was instrumented with flow meters, thermocouples, pressure transducers and both high speed and normal speed video cameras. A low boiling point surrogate fluid, FC-72, was selected based on scaling analyses using preliminary designs for operational systems. Preliminary results are presented which include flow regime transitions and some observations regarding system stability.

Miniature infrared data acquisition and telemetry system

NASA Technical Reports Server (NTRS)

Stokes, J. H.; Ward, S. M.

1985-01-01

The Miniature Infrared Data Acquisition and Telemetry (MIRDAT) Phase 1 study was performed to determine the technical and commercial feasibility of producing a miniaturized electro-optical telemetry system. This system acquires and transmits experimental data from aircraft scale models for realtime monitoring in wind tunnels. During the Phase 1 study, miniature prototype MIRDAT telemetry devices were constructed, successfully tested in the laboratory and delivered to the user for wind tunnel testing. A search was conducted for commercially available components and advanced hybrid techniques to further miniaturize the system during Phase 2 development. A design specification was generated from laboratory testing, user requirements and discussions with component manufacturers. Finally, a preliminary design of the proposed MIRDAT system was documented for Phase 2 development.

Surface based factory for the production of life support and technology support products

NASA Technical Reports Server (NTRS)

1987-01-01

The presence of a manned space colony on Mars may be expected to involve three phases in the utilization of planetary resources: (1) survival phase in which air, water, and food are produced, (2) self sufficiency phase in which chemicals, fuels, pharmaceuticals, polymers, and metals are produced, and (3) export to earth of materials and technology 1 phase in which the unique advantage of the extraterrestrial environment is fully exploited. The Advanced Design Project is administered as an interdisciplinary effort involving students and faculty throughout the College of Engineering. Senior students from Chemical, Civil, Electrical, and Mechanical Engineering are participating as a team. Multi discipline interfacing and coordination are stressed throughout the project. An interdisciplinary senior design course was developed and offered in the Spring of 1987. The first task of the survival phase is that of providing a supply of water and air adequate to support a ten person colony. The project has been divided into three subgroups: (1) design of a manufacturing and storage facility for air, (2) search and drill for water or water-bearing materials, and (3) retrieve, purify, and store potable water. The conceptual design phase has been completed and the project is being documented. The second task of the survival phase is that of providing a replenish able food supply. This task has two requirements: producing a supply of protein and providing an environment for growing plants for food. For the first requirement, we considered the design of a bioreactor system capable of growing beef cells for protein production. For the second, a design must be developed for a manufacturing system to produce materials needed to build a greenhouse farm.

Magnetic liquefier for hydrogen

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1992-12-31

This document summarizes work done at the Astronautics Technology Center of the Astronautics Corporation of America (ACA) in Phase 1 of a four phase program leading to the development of a magnetic liquefier for hydrogen. The project involves the design, fabrication, installation, and operation of a hydrogen liquefier providing significantly reduced capital and operating costs, compared to present liquefiers. To achieve this goal, magnetic refrigeration, a recently developed, highly efficient refrigeration technology, will be used for the liquefaction process. Phase 1 project tasks included liquefier conceptual design and analysis, preliminary design of promising configurations, design selection, and detailed design ofmore » the selected design. Fabrication drawings and vendor specifications for the selected design were completed during detailed design. The design of a subscale, demonstration magnetic hydrogen liquefier represents a significant advance in liquefaction technology. The cost reductions that can be realized in hydrogen liquefaction in both the subscale and, more importantly, in the full-scale device are expected to have considerable impact on the use of liquid hydrogen in transportation, chemical, and electronic industries. The benefits to the nation from this technological advance will continue to have importance well into the 21st century.« less

Calculating phase diagrams using PANDAT and panengine

NASA Astrophysics Data System (ADS)

Chen, S.-L.; Zhang, F.; Xie, F.-Y.; Daniel, S.; Yan, X.-Y.; Chang, Y. A.; Schmid-Fetzer, R.; Oates, W. A.

2003-12-01

Knowledge of phase equilibria or phase diagrams and thermodynamic properties is important in alloy design and materials-processing simulation. In principle, stable phase equilibrium is uniquely determined by the thermodynamic properties of the system, such as the Gibbs energy functions of the phases. PANDAT, a new computer software package for multicomponent phase-diagram calculation, was developed under the guidance of this principle.

One approach for evaluating the Distributed Computing Design System (DCDS)

NASA Technical Reports Server (NTRS)

Ellis, J. T.

1985-01-01

The Distributed Computer Design System (DCDS) provides an integrated environment to support the life cycle of developing real-time distributed computing systems. The primary focus of DCDS is to significantly increase system reliability and software development productivity, and to minimize schedule and cost risk. DCDS consists of integrated methodologies, languages, and tools to support the life cycle of developing distributed software and systems. Smooth and well-defined transistions from phase to phase, language to language, and tool to tool provide a unique and unified environment. An approach to evaluating DCDS highlights its benefits.

Shuttle unified navigation filter, revision 1

NASA Technical Reports Server (NTRS)

Muller, E. S., Jr.

1973-01-01

Equations designed to meet the navigation requirements of the separate shuttle mission phases are presented in a series of reports entitled, Space Shuttle GN and C Equation Document. The development of these equations is based on performance studies carried out for each particular mission phase. Although navigation equations have been documented separately for each mission phase, a single unified navigation filter design is embodied in these separate designs. The purpose of this document is to present the shuttle navigation equations in a form in which they would most likely be coded-as the single unified navigation filter used in each mission phase. This document will then serve as a single general reference for the navigation equations replacing each of the individual mission phase navigation documents (which may still be used as a description of a particular navigation phase).

Airfoil Vibration Dampers program

NASA Technical Reports Server (NTRS)

Cook, Robert M.

1991-01-01

The Airfoil Vibration Damper program has consisted of an analysis phase and a testing phase. During the analysis phase, a state-of-the-art computer code was developed, which can be used to guide designers in the placement and sizing of friction dampers. The use of this computer code was demonstrated by performing representative analyses on turbine blades from the High Pressure Oxidizer Turbopump (HPOTP) and High Pressure Fuel Turbopump (HPFTP) of the Space Shuttle Main Engine (SSME). The testing phase of the program consisted of performing friction damping tests on two different cantilever beams. Data from these tests provided an empirical check on the accuracy of the computer code developed in the analysis phase. Results of the analysis and testing showed that the computer code can accurately predict the performance of friction dampers. In addition, a valuable set of friction damping data was generated, which can be used to aid in the design of friction dampers, as well as provide benchmark test cases for future code developers.

Summary of development of 70 MW class model superconducting generator--research and development of superconducting for electric power application

NASA Astrophysics Data System (ADS)

Oishi, Ikuo; Nishijima, Kenichi

2002-03-01

A 70 MW class superconducting model generator was designed, manufactured, and tested from 1988 to 1999 as Phase I, which was Japan's national project on applications of superconducting technologies to electric power apparatuses that was commissioned by NEDO as part of New Sunshine Program of AIST and MITI. Phase II then is now being carried out by almost same organization as Phase I. With the development of the 70 MW class superconducting model generator, technologies for a 200 MW class pilot generator were established. The world's largest output (79 MW), world's longest continuous operation (1500 h), and other sufficient characteristics were achieved on the 70 MW class superconducting model generator, and key technologies of design and manufacture required for the 200 MW class pilot generator were established. This project contributed to progress of R&D of power apparatuses. Super-GM has started the next project (Phase II), which shall develop the key technologies for larger-capacity and more-compact machine and is scheduled from 2000 to 2003. Phase II shall be the first step for commercialization of superconducting generator.

Space station WP-04 power system. Volume 2: Study results

NASA Technical Reports Server (NTRS)

Hallinan, G. J.

1987-01-01

Results of the phase B study contract for the definition of the space station Electric Power System (EPS) are presented in detail along with backup information and supporting data. Systems analysis and trades, preliminary design, advanced development, customer accommodations, operations planning, product assurance, and design and development phase planning are addressed. The station design is a hybrid approach which provides user power of 25 kWe from the photovoltaic subsystem and 50 kWe from the solar dynamic subsystem. The electric power is distributed to users as a utility service; single phase at a frequency of 20 kHz and voltage of 440VAC. The solar array NiH2 batteries of the photovoltaic subsystem are based on commonality to those used on the co-orbiting and solar platforms.

Development of a prototype two-phase thermal bus system for Space Station

NASA Technical Reports Server (NTRS)

Myron, D. L.; Parish, R. C.

1987-01-01

This paper describes the basic elements of a pumped two-phase ammonia thermal control system designed for microgravity environments, the development of the concept into a Space Station flight design, and design details of the prototype to be ground-tested in the Johnson Space Center (JSC) Thermal Test Bed. The basic system concept is one of forced-flow heat transport through interface heat exchangers with anhydrous ammonia being pumped by a device expressly designed for two-phase fluid management in reduced gravity. Control of saturation conditions, and thus system interface temperatures, is accomplished with a single central pressure regulating valve. Flow control and liquid inventory are controlled by passive, nonelectromechanical devices. Use of these simple control elements results in minimal computer controls and high system reliability. Building on the basic system concept, a brief overview of a potential Space Station flight design is given. Primary verification of the system concept will involve testing at JSC of a 25-kW ground test article currently in fabrication.

High Cycle Fatigue (HCF) Science and Technology Program 2002 Annual Report

DTIC Science & Technology

2003-08-01

Turbine Engine Airfoils, Phase I 4.3 Probabilistic Design of Turbine Engine Airfoils, Phase II 4.4 Probabilistic Blade Design System 4.5...XTL17/SE2 7.4 Conclusion 8.0 TEST AND EVALUATION 8.1 Characterization Test Protocol 8.2 Demonstration Test Protocol 8.3 Development of Multi ...transparent and opaque overlays for processing. The objective of the SBIR Phase I program was to identify and evaluate promising methods for

Quality by Design approach in the development of hydrophilic interaction liquid chromatographic method for the analysis of iohexol and its impurities.

PubMed

Jovanović, Marko; Rakić, Tijana; Tumpa, Anja; Jančić Stojanović, Biljana

2015-06-10

This study presents the development of hydrophilic interaction liquid chromatographic method for the analysis of iohexol, its endo-isomer and three impurities following Quality by Design (QbD) approach. The main objective of the method was to identify the conditions where adequate separation quality in minimal analysis duration could be achieved within a robust region that guarantees the stability of method performance. The relationship between critical process parameters (acetonitrile content in the mobile phase, pH of the water phase and ammonium acetate concentration in the water phase) and critical quality attributes is created applying design of experiments methodology. The defined mathematical models and Monte Carlo simulation are used to evaluate the risk of uncertainty in models prediction and incertitude in adjusting the process parameters and to identify the design space. The borders of the design space are experimentally verified and confirmed that the quality of the method is preserved in this region. Moreover, Plackett-Burman design is applied for experimental robustness testing and method is fully validated to verify the adequacy of selected optimal conditions: the analytical column ZIC HILIC (100 mm × 4.6 mm, 5 μm particle size); mobile phase consisted of acetonitrile-water phase (72 mM ammonium acetate, pH adjusted to 6.5 with glacial acetic acid) (86.7:13.3) v/v; column temperature 25 °C, mobile phase flow rate 1 mL min(-1), wavelength of detection 254 nm. Copyright © 2015 Elsevier B.V. All rights reserved.

An Expert System-Driven Method for Parametric Trajectory Optimization During Conceptual Design

NASA Technical Reports Server (NTRS)

Dees, Patrick D.; Zwack, Mathew R.; Steffens, Michael; Edwards, Stephen; Diaz, Manuel J.; Holt, James B.

2015-01-01

During the early phases of engineering design, the costs committed are high, costs incurred are low, and the design freedom is high. It is well documented that decisions made in these early design phases drive the entire design's life cycle cost. In a traditional paradigm, key design decisions are made when little is known about the design. As the design matures, design changes become more difficult in both cost and schedule to enact. The current capability-based paradigm, which has emerged because of the constrained economic environment, calls for the infusion of knowledge usually acquired during later design phases into earlier design phases, i.e. bringing knowledge acquired during preliminary and detailed design into pre-conceptual and conceptual design. An area of critical importance to launch vehicle design is the optimization of its ascent trajectory, as the optimal trajectory will be able to take full advantage of the launch vehicle's capability to deliver a maximum amount of payload into orbit. Hence, the optimal ascent trajectory plays an important role in the vehicle's affordability posture yet little of the information required to successfully optimize a trajectory is known early in the design phase. Thus, the current paradigm of optimizing ascent trajectories involves generating point solutions for every change in a vehicle's design parameters. This is often a very tedious, manual, and time-consuming task for the analysts. Moreover, the trajectory design space is highly non-linear and multi-modal due to the interaction of various constraints. When these obstacles are coupled with the Program to Optimize Simulated Trajectories (POST), an industry standard program to optimize ascent trajectories that is difficult to use, expert trajectory analysts are required to effectively optimize a vehicle's ascent trajectory. Over the course of this paper, the authors discuss a methodology developed at NASA Marshall's Advanced Concepts Office to address these issues. The methodology is two-fold: first, capture the heuristics developed by human analysts over their many years of experience; and secondly, leverage the power of modern computing to evaluate multiple trajectories simultaneously and therefore enable the exploration of the trajectory's design space early during the pre- conceptual and conceptual phases of design. This methodology is coupled with design of experiments in order to train surrogate models, which enables trajectory design space visualization and parametric optimal ascent trajectory information to be available when early design decisions are being made.

Study and development of CW room temperature rebuncher for SARAF accelerator

NASA Astrophysics Data System (ADS)

Kaizer, B.; Rodnizki, J.; Farber, E.; Perry, A.; Danon, L.; Horvitz, Z.; Mazor, O.; Friedman, A.; Di Giacomo, M.; Leyge, J.-F.; Michel, M.; Toussaint, P.

2017-11-01

The SARAF 176 MHz accelerator is designed to provide CW proton/deuteron beams up to 5 mA current and 40 MeV accelerated ion energy. Phase I of SARAF (up to 4-5 MeV) has been installed, commissioned, and is available for experimental work. Phase II of SARAF is currently in the design and first prototyping stage and will contain longer MEBT with three rebunchers and four cryomodules, each consisting of SC HWRs and solenoids. Phase II MEBT line is designed to follow a 1.3 MeV/u RFQ, is 4.5 m long, and contains three 176 MHz rebunchers providing a field integral of 105 kV. Different rebuncher configurations have been studied in order to minimize the RF losses and maximize the shunt impedance. Different apertures have also been tested with the 40 mm diameter required by beam dynamics. The simulations were done using CST Microwave Studio. CEA leads the design for SARAF phase II linac including the MEBT rebunchers and has studied a mixed solid copper and Cu plated stainless steel, 3-gap cavity. SNRC is developing a 4-gap OFHC copper rebuncher as a risk reduction. Both designs are presented and discussed in the paper.

Contextualizing and assessing the social capital of seniors in congregate housing residences: study design and methods

PubMed Central

Moore, Spencer; Shiell, Alan; Haines, Valerie; Riley, Therese; Collier, Carrie

2005-01-01

Background This article discusses the study design and methods used to contextualize and assess the social capital of seniors living in congregate housing residences in Calgary, Alberta. The project is being funded as a pilot project under the Institute of Aging, Canadian Institutes for Health Research. Design/Methods Working with seniors living in 5 congregate housing residencies in Calgary, the project uses a mixed method approach to develop grounded measures of the social capital of seniors. The project integrates both qualitative and quantitative methods in a 3-phase research design: 1) qualitative, 2) quantitative, and 3) qualitative. Phase 1 uses gender-specific focus groups; phase 2 involves the administration of individual surveys that include a social network module; and phase 3 uses anamolous-case interviews. Not only does the study design allow us to develop grounded measures of social capital but it also permits us to test how well the three methods work separately, and how well they fit together to achieve project goals. This article describes the selection of the study population, the multiple methods used in the research and a brief discussion of our conceptualization and measurement of social capital. PMID:15836784

A review of ISEAS design

NASA Technical Reports Server (NTRS)

Bykat, Alex

1993-01-01

The Space Station Freedom will offer facilities for experimentation and testing not available and not feasible or possible on earth. Due to a restricted space availability on board, the experimentation equipment and its organization will be frequently changing. This requires careful attention to electromagnetic compatibility between experimentation and other SSF equipment. To analyze the interactions between different equipment modules, a software system ISEAS is under development. Development of ISEAS was approached in two phases. In the 1st phase a PC version prototype of ISEAS was developed. In the 2nd phase, the PC prototype will be adapted to a VAX range of computers. The purpose of this paper is to review the design of the VAX version of ISEAS, and to recommend any suitable changes.

Tropical Rainfall Measuring Mission (TRMM) project. VI - Spacecraft, scientific instruments, and launching rocket. Part 1 - Spacecraft

NASA Technical Reports Server (NTRS)

Keating, Thomas; Ihara, Toshio; Miida, Sumio

1990-01-01

A cooperative United States/Japan study was made for one year from 1987 to 1988 regarding the feasibility of the Tropical Rainfall Measuring Mission (TRMM). As part of this study a phase-A-level design of spacecraft for TRMM was developed by NASA/GSFC, and the result was documented in a feasibility study. The phase-A-level design is developed for the TRMM satellite utilizing a multimission spacecraft.

Development strategy and process models for phased automation of design and digital manufacturing electronics

NASA Astrophysics Data System (ADS)

Korshunov, G. I.; Petrushevskaya, A. A.; Lipatnikov, V. A.; Smirnova, M. S.

2018-03-01

The strategy of quality of electronics insurance is represented as most important. To provide quality, the processes sequence is considered and modeled by Markov chain. The improvement is distinguished by simple database means of design for manufacturing for future step-by-step development. Phased automation of design and digital manufacturing electronics is supposed. The MatLab modelling results showed effectiveness increase. New tools and software should be more effective. The primary digital model is proposed to represent product in the processes sequence from several processes till the whole life circle.

Design and Stability of an On-Orbit Attitude Control System Using Reaction Control Thrusters

NASA Technical Reports Server (NTRS)

Hall, Robert A.; Hough, Steven; Orphee, Carolina; Clements, Keith

2015-01-01

Principles for the design and stability of a spacecraft on-orbit attitude control system employing on-off Reaction Control System (RCS) thrusters is presented. Both the vehicle dynamics and the control system actuators are inherently nonlinear, hence traditional linear control system design approaches are not directly applicable. This paper has three main aspects: It summarizes key RCS control System design principles from the Space Shuttle and Space Station programs, it demonstrates a new approach to develop a linear model of a phase plane control system using describing functions, and applies each of these to the initial development of the NASA's next generation of upper stage vehicles. Topics addressed include thruster hardware specifications, phase plane design and stability, jet selection approaches, filter design metrics, and automaneuver logic.

Intelligent Engine Systems: Bearing System

NASA Technical Reports Server (NTRS)

Singh, Arnant P.

2008-01-01

The overall requirements necessary for sensing bearing distress and the related criteria to select a particular rotating sensor were established during the phase I. The current phase II efforts performed studies to evaluate the Robustness and Durability Enhancement of the rotating sensors, and to design, and develop the Built-in Telemetry System concepts for an aircraft engine differential sump. A generic test vehicle that can test the proposed bearing diagnostic system was designed, developed, and built. The Timken Company, who also assisted with testing the GE concept of using rotating sensors for the differential bearing diagnostics during previous phase, was selected as a subcontractor to assist General Electric (GE) for the design, and procurement of the test vehicle. A purchase order was prepared to define the different sub-tasks, and deliverables for this task. The University of Akron was selected to provide the necessary support for installing, and integrating the test vehicle with their newly designed test facility capable of simulating the operating environment for the planned testing. The planned testing with good and damaged bearings will be on hold pending further continuation of this effort during next phase.

Risk Evaluation in the Pre-Phase A Conceptual Design of Spacecraft

NASA Technical Reports Server (NTRS)

Fabisinski, Leo L., III; Maples, Charlotte Dauphne

2010-01-01

Typically, the most important decisions in the design of a spacecraft are made in the earliest stages of its conceptual design the Pre-Phase A stages. It is in these stages that the greatest number of design alternatives is considered, and the greatest number of alternatives is rejected. The focus of Pre-Phase A conceptual development is on the evaluation and comparison of whole concepts and the larger-scale systems comprising those concepts. This comparison typically uses general Figures of Merit (FOMs) to quantify the comparative benefits of designs and alternative design features. Along with mass, performance, and cost, risk should be one of the major FOMs in evaluating design decisions during the conceptual design phases. However, risk is often given inadequate consideration in conceptual design practice. The reasons frequently given for this lack of attention to risk include: inadequate mission definition, lack of rigorous design requirements in early concept phases, lack of fidelity in risk assessment methods, and under-evaluation of risk as a viable FOM for design evaluation. In this paper, the role of risk evaluation in early conceptual design is discussed. The various requirements of a viable risk evaluation tool at the Pre-Phase A level are considered in light of the needs of a typical spacecraft design study. A technique for risk identification and evaluation is presented. The application of the risk identification and evaluation approach to the conceptual design process is discussed. Finally, a computational tool for risk profiling is presented and applied to assess the risk for an existing Pre-Phase A proposal. The resulting profile is compared to the risks identified for the proposal by other means.

Optical Design of the WFIRST Phase-A Integral Field Channel

NASA Technical Reports Server (NTRS)

Gao, Guangjun; Pasquale, Bert A.; Marx, Catherine T.; Chambers, Victor

2017-01-01

WFIRST is one of NASA's Decadal Survey Missions and is currently in Phase-A development. The optical design of the WFIRST Integral Field Channel (IFC), one of three main optical channels of WFIRST, is presented, and the evolution of the IFC channel since Mission Concept Review (MCR, end of Pre-Phase A) is discussed. The IFC has two sub-channels: Supernova (IFC-S) and Galaxy (IFC-G) channels, with Fields of View of 3"x4.5" and 4.2"x9" respectively, and approximately R 75 spectral analysis over waveband 0.42 approximately 2.0 micrometers. The Phase-A IFC optical design meets image quality requirements over the FOV areas while balancing cost and volume constraints.

RASSP final technical report

NASA Astrophysics Data System (ADS)

1992-10-01

The overall objective of the DARPA/Tri-Service RASSP program is to demonstrate a capability to rapidly specify, produce, and yield domain-specific, affordable signal processors for use in Department of Defense systems such as automatic target acquisition, tracking, and recognition, electronic countermeasures, communications, and SIGINT. The objective of the study phase is to specify a recommended program plan for the government to use as a template for procurement of the RASSP design system and demonstration program. To accomplish that objective, the study phase program tasks are to specify a development methodology for signal processors (adaptable to various organizational design styles, and application areas), analyze the requirements in CAD/CAE tools to support the development methodology, identify the state and development plans of the industry relative to this area, and to recommend the additional developments not currently being addressed by the industry, which are recommended as RASSP developments. In addition, the RASSP study phase will define a linking approach for electronically linking design centers to manufacturing centers so a complete cycle for prototyping can be accomplished with significantly reduced cycle time.

Innovative grinding wheel design for cost-effective machining of advanced ceramics

DOE Office of Scientific and Technical Information (OSTI.GOV)

Licht, R.H.; Kuo, P.; Liu, S.

2000-05-01

This Final Report covers the Phase II Innovative Grinding Wheel (IGW) program in which Norton Company successfully developed a novel grinding wheel for cost-effective cylindrical grinding of advanced ceramics. In 1995, Norton Company successfully completed the 16-month Phase I technical effort to define requirements, design, develop, and evaluate a next-generation grinding wheel for cost-effective cylindrical grinding of advanced ceramics using small prototype wheels. The Phase II program was initiated to scale-up the new superabrasive wheel specification to larger diameters, 305-mm to 406-mm, required for most production grinding of cylindrical ceramic parts, and to perform in-house and independent validation grinding tests.

Shuttle: forever young?

PubMed

Sietzen, Frank

2002-01-01

NASA has started a 4-phase program of upgrades designed to increase safety and extend use of the space shuttles through the year 2020. Phase I is aimed at improving vehicle safety and supporting the space station. Phase II is aimed at combating obsolescence and includes a checkout launch and control system and protection from micrometeoroids and orbital debris. Phase III is designed to expand or enhance the capabilities of the shuttle and includes development of an auxiliary power unit, avionics, a channel-wall nozzle, extended nose landing gear, long-life fuel cells, a nontoxic orbital maneuvering system/reaction control system, and a water membrane evaporator. Phase IV is aimed at design of system changes that would alter the shuttle mold line and configuration; projects include a five-segment solid rocket booster, liquid flyback boosters, and a crew escape module.

Self Improving Methods for Materials and Process Design

DTIC Science & Technology

1998-08-31

using inductive coupling techniques. The first phase of the work focuses on developing an artificial neural network learning for function approximation...developing an artificial neural network learning algorithm for time-series prediction. The third phase of the work focuses on model selection. We have

A new trial design to accelerate tuberculosis drug development: the Phase IIC Selection Trial with Extended Post-treatment follow-up (STEP).

PubMed

Phillips, Patrick P J; Dooley, Kelly E; Gillespie, Stephen H; Heinrich, Norbert; Stout, Jason E; Nahid, Payam; Diacon, Andreas H; Aarnoutse, Rob E; Kibiki, Gibson S; Boeree, Martin J; Hoelscher, Michael

2016-03-23

The standard 6-month four-drug regimen for the treatment of drug-sensitive tuberculosis has remained unchanged for decades and is inadequate to control the epidemic. Shorter, simpler regimens are urgently needed to defeat what is now the world's greatest infectious disease killer. We describe the Phase IIC Selection Trial with Extended Post-treatment follow-up (STEP) as a novel hybrid phase II/III trial design to accelerate regimen development. In the Phase IIC STEP trial, the experimental regimen is given for the duration for which it will be studied in phase III (presently 3 or 4 months) and patients are followed for clinical outcomes of treatment failure and relapse for a total of 12 months from randomisation. Operating characteristics of the trial design are explored assuming a classical frequentist framework as well as a Bayesian framework with flat and sceptical priors. A simulation study is conducted using data from the RIFAQUIN phase III trial to illustrate how such a design could be used in practice. With 80 patients per arm, and two (2.5 %) unfavourable outcomes in the STEP trial, there is a probability of 0.99 that the proportion of unfavourable outcomes in a potential phase III trial would be less than 12 % and a probability of 0.91 that the proportion of unfavourable outcomes would be less than 8 %. With six (7.5 %) unfavourable outcomes, there is a probability of 0.82 that the proportion of unfavourable outcomes in a potential phase III trial would be less than 12 % and a probability of 0.41 that it would be less than 8 %. Simulations using data from the RIFAQUIN trial show that a STEP trial with 80 patients per arm would have correctly shown that the Inferior Regimen should not proceed to phase III and would have had a high chance (0.88) of either showing that the Successful Regimen could proceed to phase III or that it might require further optimisation. Collection of definitive clinical outcome data in a relatively small number of participants over only 12 months provides valuable information about the likelihood of success in a future phase III trial. We strongly believe that the STEP trial design described herein is an important tool that would allow for more informed decision-making and accelerate regimen development.

Quartz/fused silica chip carriers

NASA Technical Reports Server (NTRS)

1992-01-01

The primary objective of this research and development effort was to develop monolithic microwave integrated circuit (MMIC) packaging which will operate efficiently at millimeter-wave frequencies. The packages incorporated fused silica as the substrate material which was selected due to its favorable electrical properties and potential performance improvement over more conventional materials for Ka-band operation. The first step towards meeting this objective is to develop a package that meets standard mechanical and thermal requirements using fused silica and to be compatible with semiconductor devices operating up to at least 44 GHz. The second step is to modify the package design and add multilayer and multicavity capacity to allow for application specific integrated circuits (ASIC's) to control multiple phase shifters. The final step is to adapt the package design to a phased array module with integral radiating elements. The first task was a continuation of the SBIR Phase 1 work. Phase 1 identified fused silica as a viable substrate material by demonstrating various plating, machining, and adhesion properties. In Phase 2 Task 1, a package was designed and fabricated to validate these findings. Task 2 was to take the next step in packaging and fabricate a multilayer, multichip module (MCM). This package is the predecessor to the phased array module and demonstrates the ability to via fill, circuit print, laminate, and to form vertical interconnects. The final task was to build a phased array module. The radiating elements were to be incorporated into the package instead of connecting to it with wire or ribbon bonds.

The development of Drink Less: an alcohol reduction smartphone app for excessive drinkers.

PubMed

Garnett, Claire; Crane, David; West, Robert; Brown, Jamie; Michie, Susan

2018-05-04

Excessive alcohol consumption poses a serious problem for public health. Digital behavior change interventions have the potential to help users reduce their drinking. In accordance with Open Science principles, this paper describes the development of a smartphone app to help individuals who drink excessively to reduce their alcohol consumption. Following the UK Medical Research Council's guidance and the Multiphase Optimization Strategy, development consisted of two phases: (i) selection of intervention components and (ii) design and development work to implement the chosen components into modules to be evaluated further for inclusion in the app. Phase 1 involved a scoping literature review, expert consensus study and content analysis of existing alcohol apps. Findings were integrated within a broad model of behavior change (Capability, Opportunity, Motivation-Behavior). Phase 2 involved a highly iterative process and used the "Person-Based" approach to promote engagement. From Phase 1, five intervention components were selected: (i) Normative Feedback, (ii) Cognitive Bias Re-training, (iii) Self-monitoring and Feedback, (iv) Action Planning, and (v) Identity Change. Phase 2 indicated that each of these components presented different challenges for implementation as app modules; all required multiple iterations and design changes to arrive at versions that would be suitable for inclusion in a subsequent evaluation study. The development of the Drink Less app involved a thorough process of component identification with a scoping literature review, expert consensus, and review of other apps. Translation of the components into app modules required a highly iterative process involving user testing and design modification.

Understanding Preferences for Osteoporosis Information to Develop an Osteoporosis Patient Education Brochure.

PubMed

Edmonds, Stephanie W; Solimeo, Samantha L; Nguyen, Vu-Thuy; Wright, Nicole C; Roblin, Douglas W; Saag, Kenneth G; Cram, Peter

2017-01-01

Patient education materials can provide important information related to osteoporosis prevention and treatment. However, available osteoporosis education materials fail to follow best-practice guidelines for patient education. To develop an educational brochure on bone health for adults aged 50 years and older using mixed-method, semistructured interviews. This project consisted of 3 phases. In Phase 1, we developed written content that included information about osteoporosis. Additionally, we designed 2 graphic-rich brochures, Brochure A (photographs) and Brochure B (illustrations). In Phase 2, interviewers presented the text-only document and both brochure designs to 53 participants from an academic Medical Center in the Midwest and an outpatient clinic in the Southeastern region of the US. Interviewers used open- and closed-ended questions to elicit opinions regarding the brochures. In Phase 3, using feedback from Phase 2, we revised the brochure and presented it to 11 participants at a third site in the Southeastern US. Participants' comprehension of brochure text and acceptability of brochure design. We enrolled 64 participants. Most were women, white, and college-educated, with an average age of 66.1 years. Participants were able to restate the basic content of the brochure and preferred Brochure A's use of photographs. Using feedback from older adults, we developed and refined a brochure for communicating bone health information to older adults at risk of osteoporosis and fragility fractures. The methods outlined in this article may serve to guide others in developing health educational brochures for chronic medical conditions.

Design and performance analysis of generalised integrator-based controller for grid connected PV system

NASA Astrophysics Data System (ADS)

Saxena, Hemant; Singh, Alka; Rai, J. N.

2018-07-01

This article discusses the design and control of a single-phase grid-connected photovoltaic (PV) system. A 5-kW PV system is designed and integrated at the DC link of an H-bridge voltage source converter (VSC). The control of the VSC and switching logic is modelled using a generalised integrator (GI). The use of GI or its variants such as second-order GI have recently evolved for synchronisation and are being used as phase locked loop (PLL) circuits for grid integration. Design of PLL circuits and the use of transformations such as Park's and Clarke's are much easier in three-phase systems. But obtaining in-phase and quadrature components becomes an important and challenging issue in single-phase systems. This article addresses this issue and discusses an altogether different application of GI for the design of compensator based on the extraction of in-phase and quadrature components. GI is frequently used as a PLL; however, in this article, it is not used for synchronisation purposes. A new controller has been designed for a single-phase grid-connected PV system working as a single-phase active compensator. Extensive simulation results are shown for the working of integrated PV system under different atmospheric and operating conditions during daytime as well as night conditions. Experimental results showing the proposed control approach are presented and discussed for the hardware set-up developed in the laboratory.

Demonstration of improved vehicle fuel efficiency through innovative tire design, materials, and weight reduction technologies

DOE Office of Scientific and Technical Information (OSTI.GOV)

Donley, Tim

2014-12-31

Cooper completed an investigation into new tire technology using a novel approach to develop and demonstrate a new class of fuel efficient tires using innovative materials technology and tire design concepts. The objective of this work was to develop a new class of fuel efficient tires, focused on the “replacement market” that would improve overall passenger vehicle fuel efficiency by 3% while lowering the overall tire weight by 20%. A further goal of this project was to accomplish the objectives while maintaining the traction and wear performance of the control tire. This program was designed to build on what hasmore » already been accomplished in the tire industry for rolling resistance based on the knowledge and general principles developed over the past decades. Cooper’s CS4 (Figure #1) premium broadline tire was chosen as the control tire for this program. For Cooper to achieve the goals of this project, the development of multiple technologies was necessary. Six technologies were chosen that are not currently being used in the tire industry at any significant level, but that showed excellent prospects in preliminary research. This development was divided into two phases. Phase I investigated six different technologies as individual components. Phase II then took a holistic approach by combining all the technologies that showed positive results during phase one development.« less

Statistical considerations for a trial of Ebola virus disease therapeutics.

PubMed

Proschan, Michael A; Dodd, Lori E; Price, Dionne

2016-02-01

The 2014 West African outbreak of Ebola virus ravaged Liberia, Sierra Leone, and Guinea, causing hemorrhagic fever and death. The need to identify effective therapeutics was acute. The usual drug development paradigm of phase I, followed by phase II, and then phase III trials would take too long. These and other factors led to the design of a clinical trial of Ebola virus disease therapeutics that differs from more conventional clinical trial designs. This article describes the Ebola virus disease medical countermeasures trial design and the thinking behind it. © The Author(s) 2016.

Study on the Preliminary Design of ARGO-M Operation System

NASA Astrophysics Data System (ADS)

Seo, Yoon-Kyung; Lim, Hyung-Chul; Rew, Dong-Young; Jo, Jung Hyun; Park, Jong-Uk; Park, Eun-Seo; Park, Jang-Hyun

2010-12-01

Korea Astronomy and Space Science Institute has been developing one mobile satellite laser ranging system named as accurate ranging system for geodetic observation-mobile (ARGO-M). Preliminary design of ARGO-M operation system (AOS) which is one of the ARGO-M subsystems was completed in 2009. Preliminary design results are applied to the following development phase by performing detailed design with analysis of pre-defined requirements and analysis of the derived specifications. This paper addresses the preliminary design of the whole AOS. The design results in operation and control part which is a key part in the operation system are described in detail. Analysis results of the interface between operation-supporting hardware and the control computer are summarized, which is necessary in defining the requirements for the operation-supporting hardware. Results of this study are expected to be used in the critical design phase to finalize the design process.

C-Band Airport Surface Communications System Standards Development. Phase II Final Report. Volume 2: Test Bed Performance Evaluation and Final AeroMACS Recommendations

NASA Technical Reports Server (NTRS)

Hall, Edward; Magner, James

2011-01-01

This report is provided as part of ITT s NASA Glenn Research Center Aerospace Communication Systems Technical Support (ACSTS) contract NNC05CA85C, Task 7: New ATM Requirements-Future Communications, C-Band and L-Band Communications Standard Development and was based on direction provided by FAA project-level agreements for New ATM Requirements-Future Communications. Task 7 included two subtasks. Subtask 7-1 addressed C-band (5091- to 5150-MHz) airport surface data communications standards development, systems engineering, test bed and prototype development, and tests and demonstrations to establish operational capability for the Aeronautical Mobile Airport Communications System (AeroMACS). Subtask 7-2 focused on systems engineering and development support of the L-band digital aeronautical communications system (L-DACS). Subtask 7-1 consisted of two phases. Phase I included development of AeroMACS concepts of use, requirements, architecture, and initial high-level safety risk assessment. Phase II builds on Phase I results and is presented in two volumes. Volume I is devoted to concepts of use, system requirements, and architecture, including AeroMACS design considerations. Volume II (this document) describes an AeroMACS prototype evaluation and presents final AeroMACS recommendations. This report also describes airport categorization and channelization methodologies. The purposes of the airport categorization task were (1) to facilitate initial AeroMACS architecture designs and enable budgetary projections by creating a set of airport categories based on common airport characteristics and design objectives, and (2) to offer high-level guidance to potential AeroMACS technology and policy development sponsors and service providers. A channelization plan methodology was developed because a common global methodology is needed to assure seamless interoperability among diverse AeroMACS services potentially supplied by multiple service providers.

NALDA (Naval Aviation Logistics Data Analysis) CAI (computer aided instruction)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Handler, B.H.; France, P.A.; Frey, S.C.

Data Systems Engineering Organization (DSEO) personnel developed a prototype computer aided instruction CAI system for the Naval Aviation Logistics Data Analysis (NALDA) system. The objective of this project was to provide a CAI prototype that could be used as an enhancement to existing NALDA training. The CAI prototype project was performed in phases. The task undertaken in Phase I was to analyze the problem and the alternative solutions and to develop a set of recommendations on how best to proceed. The findings from Phase I are documented in Recommended CAI Approach for the NALDA System (Duncan et al., 1987). Inmore » Phase II, a structured design and specifications were developed, and a prototype CAI system was created. A report, NALDA CAI Prototype: Phase II Final Report, was written to record the findings and results of Phase II. NALDA CAI: Recommendations for an Advanced Instructional Model, is comprised of related papers encompassing research on computer aided instruction CAI, newly developing training technologies, instructional systems development, and an Advanced Instructional Model. These topics were selected because of their relevancy to the CAI needs of NALDA. These papers provide general background information on various aspects of CAI and give a broad overview of new technologies and their impact on the future design and development of training programs. The paper within have been index separately elsewhere.« less

The space station freedom flight telerobotic servicer. The design and evolution of a dexterous space robot

NASA Astrophysics Data System (ADS)

McCain, Harry G.; Andary, James F.; Hewitt, Dennis R.; Haley, Dennis C.

The Flight Telerobotic Servicer (FTS) Project at the Goddard Space Flight Center is developing an advanced telerobotic system to assist in and reduce crew extravehicular activity (EVA) for Space Station Freedom (SSF). The FTS will provide a telerobotic capability to the Freedom Station in the early assembly phases of the program and will be employed for assembly, maintenance, and inspection applications throughout the lifetime of the space station. Appropriately configured elements of the FTS will also be employed for robotic manipulation in remote satellite servicing applications and possibly the Lunar/Mars Program. In mid-1989, the FTS entered the flight system design and implementation phase (Phase C/D) of development with the signing of the FTS prime contract with Martin Marietta Astronautics Group in Denver, Colorado. The basic FTS design is now established and can be reported on in some detail. This paper will describe the FTS flight system design and the rationale for the specific design approaches and component selections. The current state of space technology and the general nature of the FTS task dictate that the FTS be designed with sophisticated teleoperation capabilities for its initial primary operating mode. However, there are technologies, such as advanced computer vision and autonomous planning techniques currently in research and advanced development phases which would greatly enhance the FTS capabilities to perform autonomously in less structured work environments. Therefore, a specific requirement on the initial FTS design is that it has the capability to evolve as new technology becomes available. This paper will describe the FTS design approach for evolution to more autonomous capabilities. Some specific task applications of the FTS and partial automation approaches of these tasks will also be discussed in this paper.

The Space Station Freedom Flight Telerobotic Servicer: the design and evolution of a dexterous space robot.

PubMed

McCain, H G; Andary, J F; Hewitt, D R; Haley, D C

1991-01-01

The Flight Telerobotic Servicer (FTS) Project at the Goddard Space Flight Center is developing an advanced telerobotic system to assist in and reduce crew extravehicular activity (EVA) for Space Station) Freedom (SSF). The FTS will provide a telerobotic capability to the Freedom Station in the early assembly phases of the program and will be employed for assembly, maintenance, and inspection applications throughout the lifetime of the space station. Appropriately configured elements of the FTS will also be employed for robotic manipulation in remote satellite servicing applications and possibly the Lunar/Mars Program. In mid-1989, the FTS entered the flight system design and implementation phase (Phase C/D) of development with the signing of the FTS prime contract with Martin Marietta Astronautics Group in Denver, Colorado. The basic FTS design is now established and can be reported on in some detail. This paper will describe the FTS flight system design and the rationale for the specific design approaches and component selections. The current state of space technology and the nature of the FTS task dictate that the FTS be designed with sophisticated teleoperation capabilities for its initial primary operating mode. However, there are technologies, such as advanced computer vision and autonomous planning techniques currently in research and advanced development phases which would greatly enhance the FTS capabilities to perform autonomously in less structured work environments. Therefore, a specific requirement on the initial FTS design is that it has the capability to evolve as new technology becomes available. This paper will describe the FTS design approach for evolution to more autonomous capabilities. Some specific task applications of the FTS and partial automation approaches of these tasks will also be discussed in this paper.

The Space Station Freedom Flight Telerobotic Servicer: the design and evolution of a dexterous space robot

NASA Technical Reports Server (NTRS)

McCain, H. G.; Andary, J. F.; Hewitt, D. R.; Haley, D. C.

1991-01-01

The Flight Telerobotic Servicer (FTS) Project at the Goddard Space Flight Center is developing an advanced telerobotic system to assist in and reduce crew extravehicular activity (EVA) for Space Station) Freedom (SSF). The FTS will provide a telerobotic capability to the Freedom Station in the early assembly phases of the program and will be employed for assembly, maintenance, and inspection applications throughout the lifetime of the space station. Appropriately configured elements of the FTS will also be employed for robotic manipulation in remote satellite servicing applications and possibly the Lunar/Mars Program. In mid-1989, the FTS entered the flight system design and implementation phase (Phase C/D) of development with the signing of the FTS prime contract with Martin Marietta Astronautics Group in Denver, Colorado. The basic FTS design is now established and can be reported on in some detail. This paper will describe the FTS flight system design and the rationale for the specific design approaches and component selections. The current state of space technology and the nature of the FTS task dictate that the FTS be designed with sophisticated teleoperation capabilities for its initial primary operating mode. However, there are technologies, such as advanced computer vision and autonomous planning techniques currently in research and advanced development phases which would greatly enhance the FTS capabilities to perform autonomously in less structured work environments. Therefore, a specific requirement on the initial FTS design is that it has the capability to evolve as new technology becomes available. This paper will describe the FTS design approach for evolution to more autonomous capabilities. Some specific task applications of the FTS and partial automation approaches of these tasks will also be discussed in this paper.

Technology verification phase. Dynamic isotope power system. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Halsey, D.G.

1982-03-10

The Phase I requirements of the Kilowatt Isotope Power System (KIPS) program were to make a detailed Flight System Conceptual Design (FSCD) for an isotope fueled organic Rankine cycle power system and to build and test a Ground Demonstration System (GDS) which simulated as closely as possible the operational characteristics of the FSCD. The activities and results of Phase II, the Technology Verification Phase, of the program are reported. The objectives of this phase were to increase system efficiency to 18.1% by component development, to demonstrate system reliability by a 5000 h endurance test and to update the flight systemmore » design. During Phase II, system performance was improved from 15.1% to 16.6%, an endurance test of 2000 h was performed while the flight design analysis was limited to a study of the General Purpose Heat Source, a study of the regenerator manufacturing technique and analysis of the hardness of the system to a laser threat. It was concluded from these tests that the GDS is basically prototypic of a flight design; all components necessary for satisfactory operation were demonstrated successfully at the system level; over 11,000 total h of operation without any component failure attested to the inherent reliability of this type of system; and some further development is required, specifically in the area of performance. (LCL)« less

Reading Treasures. Phase I and Phase II.

ERIC Educational Resources Information Center

Kansas State Dept. of Education, Topeka.

Based on the premise that a school reading program must focus on the learner and the text, this guidebook is designed to serve as a resource for school districts, groups, or individuals involved in planning, implementing, and evaluating reading programs. The guidebook is divided into two phases. Phase 1, "Guidelines for Developing and…

Heat storage capability of a rolling cylinder using Glauber's salt

NASA Technical Reports Server (NTRS)

Herrick, C. S.; Zarnoch, K. P.

1980-01-01

The rolling cylinder phase change heat storage concept was developed to the point where a prototype design is completed and a cost analysis is prepared. A series of experimental and analytical tasks are defined to establish the thermal, mechanical, and materials behavior of rolling cylinder devices. These tasks include: analyses of internal and external heat transfer; performance and lifetime testing of the phase change materials; corrosion evaluation; development of a mathematical model; and design of a prototype and associated test equipment.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Levy, E.; Mullens, M.; Rath, P.

The Advanced Envelope Research effort will provide factory homebuilders with high performance, cost-effective envelope designs that can be effectively integrated into the plant production process while meeting the thermal requirements of the 2012 IECC standards. Given the affordable nature of manufactured homes, impact on first cost is a major consideration in developing new envelope technologies. This work is part of a multi-phase effort. Phase 1 identified seven envelope technologies and provided a preliminary assessment of three methods for building high performance walls. Phase 2 focused on developing viable product designs, manufacturing strategies, addressing code and structural issues, and cost analysismore » of the three selected options. An industry advisory committee helped narrow the research focus to perfecting a stud wall design with exterior continuous insulation (CI). Phase 3, completed in two stages, continued the design development effort, exploring and evaluating a range or methods for applying CI to factory built homes. The scope also included material selection, manufacturing and cost analysis, and prototyping and testing. During this phase, a home was built with CI, evaluated, and placed in service. The experience of building a mock up wall section with CI and then constructing on line a prototype home resolved important concerns about how to integrate the material into the production process. First steps were taken toward finding least expensive approaches for incorporating CI in standard factory building practices and a preliminary assessment suggested that even at this early stage the technology is attractive when viewed from a life cycle cost perspective.« less

76 FR 6478 - Revision to Proposed Collection; Comment Request; The National Children's Study (NCS), Vanguard...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-02-04

...: The purpose of the proposed methodological study is to continue the Vanguard phase of the National... study design elements for a prospective, national longitudinal study of child health and development. In combination, the sub-studies encompassed by the Vanguard Phase will be used to inform the design of the Main...

Variable speed gas engine-driven air compressor system

NASA Astrophysics Data System (ADS)

Morgan, J. R.; Ruggles, A. E.; Chen, T. N.; Gehret, J.

1992-11-01

Tecogen Inc. and Ingersoll-Rand Co. as a subcontractor have designed a nominal 150-hp gas engine-driven air compressor utilizing the TECODRIVE 8000 engine and the Ingersoll-Rand 178.5-mm twin screw compressor. Phase 1 included the system engineering and design, economic and applications studies, and a draft commercialization plan. Phase 2 included controls development, laboratory prototype construction, and performance testing. The testing conducted verified that the compressor meets all design specifications.

Enhancing Teachers' Technological Pedagogical Knowledge and Practices: A Professional Development Model for Technology Teachers in Malawi

ERIC Educational Resources Information Center

Chikasanda, Vanwyk Khobidi Mbubzi; Otrel-Cass, Kathrin; Williams, John; Jones, Alister

2013-01-01

This paper reports on a professional development that was designed and implemented in an attempt to broaden teachers' knowledge of the nature of technology and also enhance their technological pedagogical practices. The professional development was organised in four phases with each phase providing themes for reflection and teacher learning in…

Principle Findings from Development of a Recirculated Exhaust Gas Intake Sensor (REGIS) Enabling Cost-Effective Fuel Efficiency Improvement

DOE Office of Scientific and Technical Information (OSTI.GOV)

Schnabel, Claus

Kick-off of the Bosch scope of work for the REGIS project started in October 2012. The primary work-packages included in the Bosch scope of work were the following: overall project management, development of the EGR sensor (design of sensor element, design of protection tube, and design of mounting orientation), development of EGR system control strategy, build-up of prototype sensors, evaluation of system performance with the new sensor and the new control strategy, long-term durability testing, and development of a 2nd generation sensor concept for continued technology development after the REGIS project. The University of Clemson was a partner with Boschmore » in the REGIS project. The Clemson scope of work for the REGIS project started in June 2013. The primary work-packages included in the Clemson scope of work were the following: development of EGR system control strategy, and evaluation of system performance with the new sensor and new control strategy. This project was split into phase I, phase II and phase III. Phase I work was completed by the end of June 2014 and included the following primary work packages: development of sensor technical requirements, assembly of engine testbench at Clemson, design concept for sensor housing, connector, and mounting orientation, build-up of EGR flow test benches at Bosch, and build-up of first sensor prototypes. Phase II work was completed by the end of June 2015 and included the following primary work pack ages: development of an optimizing function and demonstration of robustness of sensor, system control strategy implementation and initial validation, completion of engine in the loop testing of developed control algorithm, completion of sensor testing including characteristic line, synthetic gas test stand, and pressure dependency characterization, demonstration of benefits of control w/o sensing via simulation, development of 2nd generation sensor concept. Notable technical achievements from phase II were the following: publication of two new technical papers by Clemson detailing the control strategies used for the EGR system control. The two papers was published in the 2016 SAE World Congress in April 2016. The titles of each paper are, “Physics-Based Exhaust Pressure and Temperature Estimation for Low Pressure EGR Control in Turbocharged Gasoline Engines,” by K. Siokos, and “A Control Algorithm for Low Pressure – EGR Systems using a Smith Predictor with Intake Oxygen Sensor Feedback”, by R. Koli. All phase III work packages have been completed. The primary work packages in phase III were the following: completion of long-term sensor durability testing, final demonstration of benefits of EGR control w/o sensing, final decision of the second generation sensor development path.« less

Space Transportation Engine Program (STEP), phase B

NASA Technical Reports Server (NTRS)

1990-01-01

The Space Transportation Engine Program (STEP) Phase 2 effort includes preliminary design and activities plan preparation that will allow smooth and time transition into a Prototype Phase and then into Phases 3, 4, and 5. A Concurrent Engineering approach using Total Quality Management (TQM) techniques, is being applied to define an oxygen-hydrogen engine. The baseline from Phase 1/1' studies was used as a point of departure for trade studies and analyses. Existing STME system models are being enhanced as more detailed module/component characteristics are determined. Preliminary designs for the open expander, closed expander, and gas generator cycles were prepared, and recommendations for cycle selection made at the Design Concept Review (DCR). As a result of July '90 DCR, and information subsequently supplied to the Technical Review Team, a gas generator cycle was selected. Results of the various Advanced Development Programs (ADP's) for the Advanced Launch Systems (ALS) were contributive to this effort. An active vehicle integration effort is supplying the NASA, Air Force, and vehicle contractors with engine parameters and data, and flowing down appropriate vehicle requirements. Engine design and analysis trade studies are being documented in a data base that was developed and is being used to organize information. To date, seventy four trade studies were input to the data base.

Flow Pattern Phenomena in Two-Phase Flow in Microchannels

NASA Astrophysics Data System (ADS)

Keska, Jerry K.; Simon, William E.

2004-02-01

Space transportation systems require high-performance thermal protection and fluid management techniques for systems ranging from cryogenic fluid management devices to primary structures and propulsion systems exposed to extremely high temperatures, as well as for other space systems such as cooling or environment control for advanced space suits and integrated circuits. Although considerable developmental effort is being expended to bring potentially applicable technologies to a readiness level for practical use, new and innovative methods are still needed. One such method is the concept of Advanced Micro Cooling Modules (AMCMs), which are essentially compact two-phase heat exchangers constructed of microchannels and designed to remove large amounts of heat rapidly from critical systems by incorporating phase transition. The development of AMCMs requires fundamental technological advancement in many areas, including: (1) development of measurement methods/systems for flow-pattern measurement/identification for two-phase mixtures in microchannels; (2) development of a phenomenological model for two-phase flow which includes the quantitative measure of flow patterns; and (3) database development for multiphase heat transfer/fluid dynamics flows in microchannels. This paper focuses on the results of experimental research in the phenomena of two-phase flow in microchannels. The work encompasses both an experimental and an analytical approach to incorporating flow patterns for air-water mixtures flowing in a microchannel, which are necessary tools for the optimal design of AMCMs. Specifically, the following topics are addressed: (1) design and construction of a sensitive test system for two-phase flow in microchannels, one which measures ac and dc components of in-situ physical mixture parameters including spatial concentration using concomitant methods; (2) data acquisition and analysis in the amplitude, time, and frequency domains; and (3) analysis of results including evaluation of data acquisition techniques and their validity for application in flow pattern determination.

ROBIS: A new tool to assess risk of bias in systematic reviews was developed

PubMed Central

Whiting, Penny; Savović, Jelena; Higgins, Julian P.T.; Caldwell, Deborah M.; Reeves, Barnaby C.; Shea, Beverley; Davies, Philippa; Kleijnen, Jos; Churchill, Rachel

2016-01-01

Objective To develop ROBIS, a new tool for assessing the risk of bias in systematic reviews (rather than in primary studies). Study Design and Setting We used four-stage approach to develop ROBIS: define the scope, review the evidence base, hold a face-to-face meeting, and refine the tool through piloting. Results ROBIS is currently aimed at four broad categories of reviews mainly within health care settings: interventions, diagnosis, prognosis, and etiology. The target audience of ROBIS is primarily guideline developers, authors of overviews of systematic reviews (“reviews of reviews”), and review authors who might want to assess or avoid risk of bias in their reviews. The tool is completed in three phases: (1) assess relevance (optional), (2) identify concerns with the review process, and (3) judge risk of bias. Phase 2 covers four domains through which bias may be introduced into a systematic review: study eligibility criteria; identification and selection of studies; data collection and study appraisal; and synthesis and findings. Phase 3 assesses the overall risk of bias in the interpretation of review findings and whether this considered limitations identified in any of the phase 2 domains. Signaling questions are included to help judge concerns with the review process (phase 2) and the overall risk of bias in the review (phase 3); these questions flag aspects of review design related to the potential for bias and aim to help assessors judge risk of bias in the review process, results, and conclusions. Conclusions ROBIS is the first rigorously developed tool designed specifically to assess the risk of bias in systematic reviews. PMID:26092286

The development of mathematics courseware for learning line and angle

NASA Astrophysics Data System (ADS)

Halim, Noor Dayana Abd; Han, Ong Boon; Abdullah, Zaleha; Yusup, Junaidah

2015-05-01

Learning software is a teaching aid which is often used in schools to increase students' motivation, attract students' attention and also improve the quality of teaching and learning process. However, the development of learning software should be followed the phases in Instructional Design (ID) Model, therefore the process can be carried out systematic and orderly. Thus, this concept paper describes the application of ADDIE model in the development of mathematics learning courseware for learning Line and Angle named CBL-Math. ADDIE model consists of five consecutive phases which are Analysis, Design, Development, Implementation and Evaluation. Each phase must be properly planned in order to achieve the objectives stated. Other than to describe the processes occurring in each phase, this paper also demonstrating how cognitive theory of multimedia learning principles are integrated in the developed courseware. The principles that applied in the courseware reduce the students' cognitive load while learning the topic of line and angle. With well prepared development process and the integration of appropriate principles, it is expected that the developed software can help students learn effectively and also increase students' achievement in the topic of Line and Angle.

Airborne electronically steerable phased array

NASA Technical Reports Server (NTRS)

1972-01-01

The results are presented of the second stage of a program for the design and development of a phased array capable of simultaneous and separate transmission and reception of radio frequency signals at S-band frequencies. The design goals of this stage were the development of three major areas of interest required for the final prototype model. These areas are the construction and testing of the low-weight, full-scale 128-element array of antenna elements, the development of the RF manifold feed system, and the construction and testing of a working module containing diplexer and transmit and receive circuits.

Fault diagnostic instrumentation design for environmental control and life support systems

NASA Technical Reports Server (NTRS)

Yang, P. Y.; You, K. C.; Wynveen, R. A.; Powell, J. D., Jr.

1979-01-01

As a development phase moves toward flight hardware, the system availability becomes an important design aspect which requires high reliability and maintainability. As part of continous development efforts, a program to evaluate, design, and demonstrate advanced instrumentation fault diagnostics was successfully completed. Fault tolerance designs for reliability and other instrumenation capabilities to increase maintainability were evaluated and studied.

Advanced Percussive Drilling Technology for Geothermal Exploration and Development

DOE Office of Scientific and Technical Information (OSTI.GOV)

Su, Jiann; Raymond, David; Prasad, Somuri

Percussive hammers are a promising advance in drilling technology for geothermal since they rely upon rock reduction mechanisms that are well-suited for use in the hard, brittle rock characteristic of geothermal formations. The project research approach and work plan includes a critical path to development of a high-temperature (HT) percussive hammer using a two phase approach. The work completed in Phase I of the project demonstrated the viability of percussive hammers and that solutions to technical challenges in design, material technology, and performance are likely to be resolved. Work completed in Phase II focused on testing the findings from Phasemore » I and evaluating performance of the materials and designs at high operating temperatures. A high-operating temperature (HOT) drilling facility was designed, built, and used to test the performance of the DTH under extreme conditions. Results from the testing indicate that a high-temperature capable hammer can be developed and is a viable alternative for use in the driller’s toolbox.« less

Automated, Parametric Geometry Modeling and Grid Generation for Turbomachinery Applications

NASA Technical Reports Server (NTRS)

Harrand, Vincent J.; Uchitel, Vadim G.; Whitmire, John B.

2000-01-01

The objective of this Phase I project is to develop a highly automated software system for rapid geometry modeling and grid generation for turbomachinery applications. The proposed system features a graphical user interface for interactive control, a direct interface to commercial CAD/PDM systems, support for IGES geometry output, and a scripting capability for obtaining a high level of automation and end-user customization of the tool. The developed system is fully parametric and highly automated, and, therefore, significantly reduces the turnaround time for 3D geometry modeling, grid generation and model setup. This facilitates design environments in which a large number of cases need to be generated, such as for parametric analysis and design optimization of turbomachinery equipment. In Phase I we have successfully demonstrated the feasibility of the approach. The system has been tested on a wide variety of turbomachinery geometries, including several impellers and a multi stage rotor-stator combination. In Phase II, we plan to integrate the developed system with turbomachinery design software and with commercial CAD/PDM software.

Job Aid Manuals for Phase I--ANALYZE of the Instructional Systems Development Model.

ERIC Educational Resources Information Center

Schulz, Russel E.; Farrell, Jean R.

Designed to supplement the descriptive authoring flowcharts in a companion volume, this manual includes specific guidance, examples, and other information referred to in the flowcharts for the implementation of the first phase of the Instructional Systems Development Model (ISD). The introductory section includes definitions; descriptions of…

The Development of a Vocational Diagnostic Program. Interim Report.

ERIC Educational Resources Information Center

Barnard, William W.

A five-phased project is described which was designed to develop more specific diagnostic procedures and instrumentation that would allow both the vocational counselor and the prospective student to determine more effectively specific occupational programs and occupational objectives for education at the postsecondary level. Phases of the project…

7 CFR 3403.4 - Three-phase program.

Code of Federal Regulations, 2011 CFR

2011-01-01

... described in this section. The first two phases are designed to assist USDA in meeting its research or... experimental research and development related to described agency requirements. These requirements, as defined...

Design study: A 186 kW lightweight diesel aircraft engine

NASA Technical Reports Server (NTRS)

Brouwers, A. P.

1980-01-01

The design of an aircraft engine capable of developing 186 kW shaft power at a 7620 m altitude is described. The 186 kW design takes into account expected new developments in aircraft designs resulting in a reassessment of the power requirements at the cruise mode operation. Based on the results of this analysis a three phase technology development program is projected resulting in production dates of 1985, 1992, and 2000.

The design and construction of the CAD-1 airship

NASA Technical Reports Server (NTRS)

Kleiner, H. J.; Schneider, R.; Duncan, J. L.

1975-01-01

The background history, design philosophy and Computer application as related to the design of the envelope shape, stress calculations and flight trajectories of the CAD-1 airship, now under construction by Canadian Airship Development Corporation are reported. A three-phase proposal for future development of larger cargo carrying airships is included.

Developing Training Exemplars for the Requisite Components of Visual Threat Detection

DTIC Science & Technology

2012-09-01

construed as an official Department of the Army position, unless so designated by other authorized documents. i REPORT DOCUMENTATION PAGE 1... Design ............................................................................................................................. 34...activities in the OE. This report presents the findings from the final research phase and consists of a discussion of the design and development of the

Development status of LE-7 fuel turbopump

NASA Astrophysics Data System (ADS)

Nakano, T.; Nagao, R.; Ohta, T.; Warashina, S.; Watanabe, H.; Oguchi, H.

The liquid hydrogen turbopump (LH2 T/P) for the LE-7 engine has been developed since 1984. The component PDR was held in June 1988 and the basic troubles occurred at the development test were solved. Next, the component CDR-1 was held in December 1989 in order to feed back the test results of prototype LH2 T/P model to the design of qualification phase T/P. So, the production of these turbopumps was admitted. Recently, the component CDR-2 was held in February 1992 to reflect the counterparts adopted for some troubles (impeller and turbine blade cracks and so on) in long-time engine tests to the design of qualification phase T/P. In the qualification phase, the hydraulic characteristics and strength in the engine operating range were examined at the LH2 T/P component test, and its endurance confirmed at the engine tests. The LH2 turbopump component test was held at NASDA Kakuda and the engine test at Tashiro and Tanegashima. This paper describes the development status of LH2 T/P, containing the design description and the content of some troubles and its counterplans.

Methyl chloride via oxyhydrochlorination of methane: A building block for chemicals and fuels from natural gas

DOE Office of Scientific and Technical Information (OSTI.GOV)

Benson, R.L.; Brown, S.S.D.; Ferguson, S.P.

1995-12-31

The objectives of this program are to (a) develop a process for converting natural gas to methyl chloride via an oxyhydrochlorination route using highly selective, stable catalysts in a fixed-bed, (b) design a reactor capable of removing the large amount of heat generated in the process so as to control the reaction, (c) develop a recovery system capable of removing the methyl chloride from the product stream and (d) determine the economics and commercial viability of the process. The general approach has been as follows: (a) design and build a laboratory scale reactor, (b) define and synthesize suitable OHC catalystsmore » for evaluation, (c) select first generation OHC catalyst for Process Development Unit (PDU) trials, (d) design, construct and startup PDU, (e) evaluate packed bed reactor design, (f) optimize process, in particular, product recovery operations, (g) determine economics of process, (h) complete preliminary engineering design for Phase II and (i) make scale-up decision and formulate business plan for Phase II. Conclusions regarding process development and catalyst development are presented.« less

Apollo experience report: Guidance and control systems - Digital autopilot design development

NASA Technical Reports Server (NTRS)

Peters, W. H.; Cox, K. J.

1973-01-01

The development of the Apollo digital autopilots (the primary attitude control systems that were used for all phases of the lunar landing mission) is summarized. This report includes design requirements, design constraints, and design philosophy. The development-process functions and the essential information flow paths are identified. Specific problem areas that existed during the development are included. A discussion is also presented on the benefits inherent in mechanizing attitude-controller logic and dynamic compensation in a digital computer.

Phase 0 study for a geothermal superheated water proof of concept facility

NASA Technical Reports Server (NTRS)

Douglass, R. H.; Pearson, R. O.

1974-01-01

A Phase 0 study for the selection of a representative liquid-dominated geothermal resource of moderate salinity and temperature is discussed. Selection and conceptual design of a nominal 10-MWe energy conversion system, and implementation planning for Phase 1: subsystem (component, experiments) and Phase 2: final design, construction, and operation of experimental research facilities are reported. The objective of the overall program is to demonstrate the technical and economic viability of utilizing moderate temperature and salinity liquid-dominated resources with acceptable environmental impact, and thus encourage commercial scale development of geothermal electrical power generation.

Nitric oxide-sensing actuators for modulating structure in lipid-based liquid crystalline drug delivery systems.

PubMed

Liu, Qingtao; Hu, Jinming; Whittaker, Michael R; Davis, Thomas P; Boyd, Ben J

2017-12-15

Herein we report on the development of a nitric oxide-sensing lipid-based liquid crystalline (LLC) system specifically designed to release encapsulated drugs on exposure to NO through a stimulated phase change. A series of nitric oxide (NO)-sensing lipids compatible with phytantriol and GMO cubic phases were designed and synthesized, and utilized in enabling nitric oxide-sensing LLC systems. The nitric oxide (NO)-sensing lipids react with nitric oxide, resulting in hydrolysis of these lipids and phase transition of the LLC system. Specifically, the N-3-aminopyridinyl myristylamine (NAPyM)+phytantriol mixture formed a lamellar phase in excess aqueous environment. The NAPyM+phytantriol LLC responded to the nitric oxide gas as a chemical stimulus which triggers a phase transition from lamellar phase to inverse cubic and hexagonal phase. The nitric oxide-triggered phase transition of the LLC accelerated the release of encapsulated model drug from the LLC bulk phase, resulting in a 15-fold increase in the diffusion coefficient compared to the starting lamellar structure. The nitric oxide-sensing LLC system has potential application in the development of smart medicines to treat nitric oxide implicated diseases. Copyright © 2017 Elsevier Inc. All rights reserved.

Development of syntax of intuition-based learning model in solving mathematics problems

NASA Astrophysics Data System (ADS)

Yeni Heryaningsih, Nok; Khusna, Hikmatul

2018-01-01

The aim of the research was to produce syntax of Intuition Based Learning (IBL) model in solving mathematics problem for improving mathematics students’ achievement that valid, practical and effective. The subject of the research were 2 classes in grade XI students of SMAN 2 Sragen, Central Java. The type of the research was a Research and Development (R&D). Development process adopted Plomp and Borg & Gall development model, they were preliminary investigation step, design step, realization step, evaluation and revision step. Development steps were as follow: (1) Collected the information and studied of theories in Preliminary Investigation step, studied about intuition, learning model development, students condition, and topic analysis, (2) Designed syntax that could bring up intuition in solving mathematics problem and then designed research instruments. They were several phases that could bring up intuition, Preparation phase, Incubation phase, Illumination phase and Verification phase, (3) Realized syntax of Intuition Based Learning model that has been designed to be the first draft, (4) Did validation of the first draft to the validator, (5) Tested the syntax of Intuition Based Learning model in the classrooms to know the effectiveness of the syntax, (6) Conducted Focus Group Discussion (FGD) to evaluate the result of syntax model testing in the classrooms, and then did the revision on syntax IBL model. The results of the research were produced syntax of IBL model in solving mathematics problems that valid, practical and effective. The syntax of IBL model in the classroom were, (1) Opening with apperception, motivations and build students’ positive perceptions, (2) Teacher explains the material generally, (3) Group discussion about the material, (4) Teacher gives students mathematics problems, (5) Doing exercises individually to solve mathematics problems with steps that could bring up students’ intuition: Preparations, Incubation, Illumination, and Verification, (6) Closure with the review of students have learned or giving homework.

A distributed finite-element modeling and control approach for large flexible structures

NASA Technical Reports Server (NTRS)

Young, K. D.

1989-01-01

An unconventional framework is described for the design of decentralized controllers for large flexible structures. In contrast to conventional control system design practice which begins with a model of the open loop plant, the controlled plant is assembled from controlled components in which the modeling phase and the control design phase are integrated at the component level. The developed framework is called controlled component synthesis (CCS) to reflect that it is motivated by the well developed Component Mode Synthesis (CMS) methods which were demonstrated to be effective for solving large complex structural analysis problems for almost three decades. The design philosophy behind CCS is also closely related to that of the subsystem decomposition approach in decentralized control.

DESIGNING PHASE 0 CANCER CLINICAL TRIALS

PubMed Central

Murgo, Anthony J.; Kummar, Shivaani; Rubinstein, Larry; Gutierrez, Martin; Collins, Jerry; Kinders, Robert; Parchment, Ralph E.; Ji, Jiuping; Steinberg, Seth M.; Yang, Sherry X.; Hollingshead, Melinda; Chen, Alice; Helman, Lee; Wiltrout, Robert; Tomaszewski, Joseph E.; Doroshow, James H.

2008-01-01

Phase 0 trials are designed primarily to evaluate the pharmacodynamic and/or pharmacokinetic properties of selected investigational agents prior to initiating more traditional phase 1 testing. One of the major objectives of phase 0 trials is to interrogate and refine a target or biomarker assay for drug effect in human samples implementing procedures developed and validated in preclinical models. Thus, close collaboration between laboratory scientists and clinical investigators is essential to the design and conduct of phase 0 trials. Given the relatively small number of patients and tissue samples, demonstrating a significant drug effect in phase 0 trials requires precise and reproducible assay procedures and innovative statistical methodology. Furthermore, phase 0 trials involving limited exposure of study agent administered at low doses and/or for a short period allows them to be initiated under the FDA Exploratory IND Guidance with less preclinical toxicity data than usually required for traditional first-in-human studies. Because of the very limited drug exposure, phase 0 trials offer no chance of therapeutic benefit, which can impede patient enrollment, particularly if invasive tumor biopsies are required. However, the challenges to accrual are not insurmountable, and well-designed and executed phase 0 trials are feasible and have great potential for improving the efficiency and success of subsequent trials, particularly those evaluating molecularly targeted agents. PMID:18559582

Integrated Design Methodology for Highly Reliable Liquid Rocket Engine

NASA Astrophysics Data System (ADS)

Kuratani, Naoshi; Aoki, Hiroshi; Yasui, Masaaki; Kure, Hirotaka; Masuya, Goro

The Integrated Design Methodology is strongly required at the conceptual design phase to achieve the highly reliable space transportation systems, especially the propulsion systems, not only in Japan but also all over the world in these days. Because in the past some catastrophic failures caused some losses of mission and vehicle (LOM/LOV) at the operational phase, moreover did affect severely the schedule delays and cost overrun at the later development phase. Design methodology for highly reliable liquid rocket engine is being preliminarily established and investigated in this study. The sensitivity analysis is systematically performed to demonstrate the effectiveness of this methodology, and to clarify and especially to focus on the correlation between the combustion chamber, turbopump and main valve as main components. This study describes the essential issues to understand the stated correlations, the need to apply this methodology to the remaining critical failure modes in the whole engine system, and the perspective on the engine development in the future.

Organic Rankine Kilowatt Isotope Power System. Final phase I report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1978-07-15

On 1 August 1975 under Department of Energy Contract EN-77-C-02-4299, Sundstrand Energy Systems commenced development of a Kilowatt Isotope Power System (KIPS) directed toward satisfying the higher power requirements of satellites of the 1980s and beyond. The KIPS is a /sup 238/PuO/sub 2/ fueled organic Rankine cycle turbine power system which will provide design output power in the range of 500 to 2000 W/sub (e)/ with a minimum of system changes. The principal objectives of the Phase 1 development effort were to: conceptually design a flight system; design a Ground Demonstration System (GDS) that is prototypic of the flight systemmore » in order to prove the feasibility of the flight system design; fabricate and assemble the GDS; and performance and endurance test the GDS using electric heaters in lieu of the isotope heat source. Results of the work performed under the Phase 1 contract to 1 July 1978 are presented.« less

Warfighting Concepts to Future Weapon System Designs (WARCON)

DTIC Science & Technology

2003-09-12

34* Software design documents rise to litigation. "* A Material List "Cost information that may support, or may * Final Engineering Process Maps be...document may include design the system as derived from the engineering design, software development, SRD. MTS Technologies, Inc. 26 FOR OFFICIAL USE...document, early in the development phase. It is software engineers produce the vision of important to establish a standard, formal the design effort. As

Feasibility study of an Integrated Program for Aerospace vehicle Design (IPAD). Volume 6: IPAD system development and operation

NASA Technical Reports Server (NTRS)

Redhed, D. D.; Tripp, L. L.; Kawaguchi, A. S.; Miller, R. E., Jr.

1973-01-01

The strategy of the IPAD implementation plan presented, proposes a three phase development of the IPAD system and technical modules, and the transfer of this capability from the development environment to the aerospace vehicle design environment. The system and technical module capabilities for each phase of development are described. The system and technical module programming languages are recommended as well as the initial host computer system hardware and operating system. The cost of developing the IPAD technology is estimated. A schedule displaying the flowtime required for each development task is given. A PERT chart gives the developmental relationships of each of the tasks and an estimate of the operational cost of the IPAD system is offered.

Design of a digital multiradian phase detector and its application in fusion plasma interferometry.

PubMed

Mlynek, A; Schramm, G; Eixenberger, H; Sips, G; McCormick, K; Zilker, M; Behler, K; Eheberg, J

2010-03-01

We discuss the circuit design of a digital multiradian phase detector that measures the phase difference between two 10 kHz square wave TTL signals and provides the result as a binary number. The phase resolution of the circuit is 1/64 period and its dynamic range is 256 periods. This circuit has been developed for fusion plasma interferometry with submillimeter waves on the ASDEX Upgrade tokamak. The results from interferometric density measurement are discussed and compared to those obtained with the previously used phase detectors, especially with respect to the occurrence of phase jumps. It is illustrated that the new phase measurement provides a powerful tool for automatic real-time validation of the measured density, which is important for feedback algorithms that are sensitive to spurious density signals.

Miniature X-band GaAs MMIC analog and bi-phase modulators for spaceborne communications applications

NASA Technical Reports Server (NTRS)

Mysoor, Narayan R.; Ali, Fazal

1992-01-01

The design concepts, analyses, and the development of GaAs monolithic microwave integrated circuit (MMIC) linear-phase and digital modulators for the next generation of spaceborne communications systems are summarized. The design approach uses a very compact lumped-element, quadrature hybrid, and MESFET-varactors to provide low-loss and well-controlled phase performance for deep-space transponder (DST) applications. The measured results of the MESFET-diode show a capacitance range of 2:1 under reverse bias, and a Q of 38 at 10 GHz. Three cascaded sections of hybrid-coupled reflection phase shifters have been modeled and simulations performed to provide an X-band (8415 +/- 50 MHz) DST phase modulator with +/-2.5 radians of peak phase deviation.

Ka-Band Multibeam Aperture Phased Array Being Developed

NASA Technical Reports Server (NTRS)

Reinhart, Richard C.; Kacpura, Thomas J.

2004-01-01

Phased-array antenna systems offer many advantages to low-Earth-orbiting satellite systems. Their large scan angles and multibeam capabilities allow for vibration-free, rapid beam scanning and graceful degradation operation for high rate downlink of data to users on the ground. Technology advancements continue to reduce the power, weight, and cost of these systems to make phased arrays a competitive alternative in comparison to the gimbled reflector system commonly used in science missions. One effort to reduce the cost of phased arrays is the development of a Ka-band multibeam aperture (MBA) phased array by Boeing Corporation under a contract jointly by the NASA Glenn Research Center and the Office of Naval Research. The objective is to develop and demonstrate a space-qualifiable dual-beam Ka-band (26.5-GHz) phased-array antenna. The goals are to advance the state of the art in Ka-band active phased-array antennas and to develop and demonstrate multibeam transmission technology compatible with spacecraft in low Earth orbit to reduce the cost of future missions by retiring certain development risks. The frequency chosen is suitable for space-to-space and space-to-ground communication links. The phased-array antenna has a radiation pattern designed by combining a set of individual radiating elements, optimized with the type of radiating elements used, their positions in space, and the amplitude and phase of the currents feeding the elements. This arrangement produces a directional radiation pattern that is proportional to the number of individual radiating elements. The arrays of interest here can scan the main beam electronically with a computerized algorithm. The antenna is constructed using electronic components with no mechanical parts, and the steering is performed electronically, without any resulting vibration. The speed of the scanning is limited primarily by the control electronics. The radiation performance degrades gracefully if a portion of the elements fail. The arrays can be constructed to conform to a mounting surface, and multibeam capability is integral to the design. However, there are challenges for mission designers using monolithic-microwave-integrated-circuit- (MMIC-) based arrays because of reduced power efficiency, higher costs, and certain system effects that result in link degradations. The multibeam aperture phased-array antenna development is attempting to address some of these issues, particularly manufacturing, costs, and system performance.

Project 8, Phase III Design: Placing an eV-Scale Limit on the Neutrino Mass using Cyclotron Radiation Emission Spectroscopy

NASA Astrophysics Data System (ADS)

Oblath, Noah; Project 8 Collaboration

2016-09-01

We report on the design concept for Phase III of the Project 8 experiment. In the third phase of Project 8 we aim to place a limit on the neutrino mass that is similar to the current limits set by tritium beta-decay experiments, mν < 2eV . From the first two phases of Project 8 we move to a novel design consisting of a 100cm3 cylindrical volume of tritium gas instrumented with two 30-element rings of inward-facing antennas. Beam-forming techniques similar to those used in radioastronomy will be employed to search for and track electron signals in the fiducial volume. This talk will present the quantitative design concept for the phased-array receiver, and illustrate how we are progressing towards the Phase IV experiment, which will have sensitivity to the neutrino mass scale allowed by the inverted mass hierarchy. This work is supported by the DOE Office of Science Early Career Research Program, and the Laboratory Directed Research and Development Program at Pacific Northwest National Laboratory.

Study of nanometer-level precise phase-shift system used in electronic speckle shearography and phase-shift pattern interferometry

NASA Astrophysics Data System (ADS)

Jing, Chao; Liu, Zhongling; Zhou, Ge; Zhang, Yimo

2011-11-01

The nanometer-level precise phase-shift system is designed to realize the phase-shift interferometry in electronic speckle shearography pattern interferometry. The PZT is used as driving component of phase-shift system and translation component of flexure hinge is developed to realize micro displacement of non-friction and non-clearance. Closed-loop control system is designed for high-precision micro displacement, in which embedded digital control system is developed for completing control algorithm and capacitive sensor is used as feedback part for measuring micro displacement in real time. Dynamic model and control model of the nanometer-level precise phase-shift system is analyzed, and high-precision micro displacement is realized with digital PID control algorithm on this basis. It is proved with experiments that the location precision of the precise phase-shift system to step signal of displacement is less than 2nm and the location precision to continuous signal of displacement is less than 5nm, which is satisfied with the request of the electronic speckle shearography and phase-shift pattern interferometry. The stripe images of four-step phase-shift interferometry and the final phase distributed image correlated with distortion of objects are listed in this paper to prove the validity of nanometer-level precise phase-shift system.

IDEAS (Integrate, Design, Assess, and Share): A Framework and Toolkit of Strategies for the Development of More Effective Digital Interventions to Change Health Behavior

PubMed Central

Robinson, Thomas N; King, Abby C

2016-01-01

Developing effective digital interventions to change health behavior has been a challenging goal for academics and industry players alike. Guiding intervention design using the best combination of approaches available is necessary if effective technologies are to be developed. Behavioral theory, design thinking, user-centered design, rigorous evaluation, and dissemination each have widely acknowledged merits in their application to digital health interventions. This paper introduces IDEAS, a step-by-step process for integrating these approaches to guide the development and evaluation of more effective digital interventions. IDEAS is comprised of 10 phases (empathize, specify, ground, ideate, prototype, gather, build, pilot, evaluate, and share), grouped into 4 overarching stages: Integrate, Design, Assess, and Share (IDEAS). Each of these phases is described and a summary of theory-based behavioral strategies that may inform intervention design is provided. The IDEAS framework strives to provide sufficient detail without being overly prescriptive so that it may be useful and readily applied by both investigators and industry partners in the development of their own mHealth, eHealth, and other digital health behavior change interventions. PMID:27986647

Learning & Personality Types: A Case Study of a Software Design Course

ERIC Educational Resources Information Center

Ahmed, Faheem; Campbell, Piers; Jaffar, Ahmad; Alkobaisi, Shayma; Campbell, Julie

2010-01-01

The software industry has continued to grow over the past decade and there is now a need to provide education and hands-on training to students in various phases of software life cycle. Software design is one of the vital phases of the software development cycle. Psychological theories assert that not everybody is fit for all kind of tasks as…

An 8-PSK TDMA uplink modulation and coding system

NASA Technical Reports Server (NTRS)

Ames, S. A.

1992-01-01

The combination of 8-phase shift keying (8PSK) modulation and greater than 2 bits/sec/Hz drove the design of the Nyquist filter to one specified to have a rolloff factor of 0.2. This filter when built and tested was found to produce too much intersymbol interference and was abandoned for a design with a rolloff factor of 0.4. The preamble is limited to 100 bit periods of the uncoded bit period of 5 ns for a maximum preamble length of 500 ns or 40 8PSK symbol times at 12.5 ns per symbol. For 8PSK modulation, the required maximum degradation of 1 dB in -20 dB cochannel interference (CCI) drove the requirement for forward error correction coding. In this contract, the funding was not sufficient to develop the proposed codec so the codec was limited to a paper design during the preliminary design phase. The mechanization of the demodulator is digital, starting from the output of the analog to digital converters which quantize the outputs of the quadrature phase detectors. This approach is amenable to an application specific integrated circuit (ASIC) replacement in the next phase of development.

Studies on Single-phase and Multi-phase Heat Pipe for LED Panel for Efficient Heat Dissipation

NASA Astrophysics Data System (ADS)

Vyshnave, K. C.; Rohit, G.; Maithreya, D. V. N. S.; Rakesh, S. G.

2017-08-01

The popularity of LED panel as a source of illumination has soared recently due to its high efficiency. However, the removal of heat that is produced in the chip is still a major challenge in its design since this has an adverse effect on its reliability. If high junction temperature develops, the colour of the emitted light may diminish over prolonged usage or even a colour shift may occur. In this paper, a solution has been developed to address this problem by using a combination of heat pipe and heat fin technology. A single-phase and a two-phase heat pipes have been designed theoretically and computational simulations carried out using ANSYS FLUENT. The results of the theoretical calculations and those obtained from the simulations are found to be in agreement with each other.

Metallic Rotor Sizing and Performance Model for Flywheel Systems

NASA Technical Reports Server (NTRS)

Moore, Camille J.; Kraft, Thomas G.

2012-01-01

The NASA Glenn Research Center (GRC) is developing flywheel system requirements and designs for terrestrial and spacecraft applications. Several generations of flywheels have been designed and tested at GRC using in-house expertise in motors, magnetic bearings, controls, materials and power electronics. The maturation of a flywheel system from the concept phase to the preliminary design phase is accompanied by maturation of the Integrated Systems Performance model, where estimating relationships are replaced by physics based analytical techniques. The modeling can incorporate results from engineering model testing and emerging detail from the design process.

A Bayesian pick-the-winner design in a randomized phase II clinical trial.

PubMed

Chen, Dung-Tsa; Huang, Po-Yu; Lin, Hui-Yi; Chiappori, Alberto A; Gabrilovich, Dmitry I; Haura, Eric B; Antonia, Scott J; Gray, Jhanelle E

2017-10-24

Many phase II clinical trials evaluate unique experimental drugs/combinations through multi-arm design to expedite the screening process (early termination of ineffective drugs) and to identify the most effective drug (pick the winner) to warrant a phase III trial. Various statistical approaches have been developed for the pick-the-winner design but have been criticized for lack of objective comparison among the drug agents. We developed a Bayesian pick-the-winner design by integrating a Bayesian posterior probability with Simon two-stage design in a randomized two-arm clinical trial. The Bayesian posterior probability, as the rule to pick the winner, is defined as probability of the response rate in one arm higher than in the other arm. The posterior probability aims to determine the winner when both arms pass the second stage of the Simon two-stage design. When both arms are competitive (i.e., both passing the second stage), the Bayesian posterior probability performs better to correctly identify the winner compared with the Fisher exact test in the simulation study. In comparison to a standard two-arm randomized design, the Bayesian pick-the-winner design has a higher power to determine a clear winner. In application to two studies, the approach is able to perform statistical comparison of two treatment arms and provides a winner probability (Bayesian posterior probability) to statistically justify the winning arm. We developed an integrated design that utilizes Bayesian posterior probability, Simon two-stage design, and randomization into a unique setting. It gives objective comparisons between the arms to determine the winner.

High-performance packaging for monolithic microwave and millimeter-wave integrated circuits

NASA Technical Reports Server (NTRS)

Shalkhauser, K. A.; Li, K.; Shih, Y. C.

1992-01-01

Packaging schemes were developed that provide low-loss, hermetic enclosure for advanced monolithic microwave and millimeter-wave integrated circuits (MMICs). The package designs are based on a fused quartz substrate material that offers improved radio frequency (RF) performance through 44 gigahertz (GHz). The small size and weight of the packages make them appropriate for a variety of applications, including phased array antenna systems. Packages were designed in two forms; one for housing a single MMIC chip, the second in the form of a multi-chip phased array module. The single chip array module was developed in three separate sizes, for chips of different geometry and frequency requirements. The phased array module was developed to address packaging directly for antenna applications, and includes transmission line and interconnect structures to support multi-element operation. All packages are fabricated using fused quartz substrate materials. As part of the packaging effort, a test fixture was developed to interface the single chip packages to conventional laboratory instrumentation for characterization of the packaged devices. The package and test fixture designs were both developed in a generic sense, optimizing performance for a wide range of possible applications and devices.

Developing an inventor support service which performs early stage market and manufacturing evaluations. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1991-10-01

American businesses are learning the difficult high cost lesson of ignoring production and market factors (producibility, unit product cost (UPC), marketability, etc) during the engineering design phase of product development. Studies have shown that the Japanese spend three times as long as Americans in the design feasibility and decision process of new product introductions and one third the amount of time in the implementation of those products. There is a 20 to 1 cost benefit on effort applied in the design phase versus the production phase of the product life cycle. The number one goal of this project was tomore » establish an organization that has, as one of its purposes, the providing of services responsive to the needs of independent inventors. The number two goal was to demonstrate the value of providing marketing and manufacturing counsel at an early stage in the product development process. The first study goal was met by providing the materials and information necessary to establish an evaluation team and an organization to handle such evaluations. The second study goal was met by demonstrating the impact of early market analysis and manufacturing considerations on product design and therefore on the description of the invention for four different inventions. These inventions were selected at various stages of development. Regardless of stage of development, the marketing and manufacturing reviews resulted in significant changes in design and/or market positioning.« less

Developing an inventor support service which performs early stage market and manufacturing evaluations. [Final Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1991-10-01

American businesses are learning the difficult high cost lesson of ignoring production and market factors (producibility, unit product cost (UPC), marketability, etc) during the engineering design phase of product development. Studies have shown that the Japanese spend three times as long as Americans in the design feasibility and decision process of new product introductions and one third the amount of time in the implementation of those products. There is a 20 to 1 cost benefit on effort applied in the design phase versus the production phase of the product life cycle. The number one goal of this project was tomore » establish an organization that has, as one of its purposes, the providing of services responsive to the needs of independent inventors. The number two goal was to demonstrate the value of providing marketing and manufacturing counsel at an early stage in the product development process. The first study goal was met by providing the materials and information necessary to establish an evaluation team and an organization to handle such evaluations. The second study goal was met by demonstrating the impact of early market analysis and manufacturing considerations on product design and therefore on the description of the invention for four different inventions. These inventions were selected at various stages of development. Regardless of stage of development, the marketing and manufacturing reviews resulted in significant changes in design and/or market positioning.« less

General approach and scope. [rotor blade design optimization

NASA Technical Reports Server (NTRS)

Adelman, Howard M.; Mantay, Wayne R.

1989-01-01

This paper describes a joint activity involving NASA and Army researchers at the NASA Langley Research Center to develop optimization procedures aimed at improving the rotor blade design process by integrating appropriate disciplines and accounting for all of the important interactions among the disciplines. The disciplines involved include rotor aerodynamics, rotor dynamics, rotor structures, airframe dynamics, and acoustics. The work is focused on combining these five key disciplines in an optimization procedure capable of designing a rotor system to satisfy multidisciplinary design requirements. Fundamental to the plan is a three-phased approach. In phase 1, the disciplines of blade dynamics, blade aerodynamics, and blade structure will be closely coupled, while acoustics and airframe dynamics will be decoupled and be accounted for as effective constraints on the design for the first three disciplines. In phase 2, acoustics is to be integrated with the first three disciplines. Finally, in phase 3, airframe dynamics will be fully integrated with the other four disciplines. This paper deals with details of the phase 1 approach and includes details of the optimization formulation, design variables, constraints, and objective function, as well as details of discipline interactions, analysis methods, and methods for validating the procedure.

Optimization of Primary Drying in Lyophilization during Early Phase Drug Development using a Definitive Screening Design with Formulation and Process Factors.

PubMed

Goldman, Johnathan M; More, Haresh T; Yee, Olga; Borgeson, Elizabeth; Remy, Brenda; Rowe, Jasmine; Sadineni, Vikram

2018-06-08

Development of optimal drug product lyophilization cycles is typically accomplished via multiple engineering runs to determine appropriate process parameters. These runs require significant time and product investments, which are especially costly during early phase development when the drug product formulation and lyophilization process are often defined simultaneously. Even small changes in the formulation may require a new set of engineering runs to define lyophilization process parameters. In order to overcome these development difficulties, an eight factor definitive screening design (DSD), including both formulation and process parameters, was executed on a fully human monoclonal antibody (mAb) drug product. The DSD enables evaluation of several interdependent factors to define critical parameters that affect primary drying time and product temperature. From these parameters, a lyophilization development model is defined where near optimal process parameters can be derived for many different drug product formulations. This concept is demonstrated on a mAb drug product where statistically predicted cycle responses agree well with those measured experimentally. This design of experiments (DoE) approach for early phase lyophilization cycle development offers a workflow that significantly decreases the development time of clinically and potentially commercially viable lyophilization cycles for a platform formulation that still has variable range of compositions. Copyright © 2018. Published by Elsevier Inc.

UNIVERSITY OF ARIZONA CROSS-BORDER WATER TECHNOLOGY COLLABORATION

EPA Science Inventory

The outcome of Phase I of the University of Arizona Cross-border Water Technology Collaboration project was the development and testing of solar distillation designs and selection of the final design for implementation that could be built in a developing country...

A ground based phase control system for the solar power satellite. Executive summary, volume 1, phase 3

NASA Technical Reports Server (NTRS)

Chie, C. M.

1980-01-01

The Solar Power Satellite (SPS) concept and the reference phase control system investigated in earlier efforts are reviewed. A summary overview of the analysis and selection of the pilot signal and power transponder design is presented along with the SOLARSIM program development and the simulated SPS phase control performance. Evaluations of the ground based phase control system as an alternate phase control concept are summarized.

Low noise buffer amplifiers and buffered phase comparators for precise time and frequency measurement and distribution

NASA Technical Reports Server (NTRS)

Eichinger, R. A.; Dachel, P.; Miller, W. H.; Ingold, J. S.

1982-01-01

Extremely low noise, high performance, wideband buffer amplifiers and buffered phase comparators were developed. These buffer amplifiers are designed to distribute reference frequencies from 30 KHz to 45 MHz from a hydrogen maser without degrading the hydrogen maser's performance. The buffered phase comparators are designed to intercompare the phase of state of the art hydrogen masers without adding any significant measurement system noise. These devices have a 27 femtosecond phase stability floor and are stable to better than one picosecond for long periods of time. Their temperature coefficient is less than one picosecond per degree C, and they have shown virtually no voltage coefficients.

Bioremediation of chlorpyrifos contaminated soil by two phase bioslurry reactor: Processes evaluation and optimization by Taguchi's design of experimental (DOE) methodology.

PubMed

Pant, Apourv; Rai, J P N

2018-04-15

Two phase bioreactor was constructed, designed and developed to evaluate the chlorpyrifos remediation. Six biotic and abiotic factors (substrate-loading rate, slurry phase pH, slurry phase dissolved oxygen (DO), soil water ratio, temperature and soil micro flora load) were evaluated by design of experimental (DOE) methodology employing Taguchi's orthogonal array (OA). The selected six factors were considered at two levels L-8 array (2^7, 15 experiments) in the experimental design. The optimum operating conditions obtained from the methodology showed enhanced chlorpyrifos degradation from 283.86µg/g to 955.364µg/g by overall 70.34% of enhancement. In the present study, with the help of few well defined experimental parameters a mathematical model was constructed to understand the complex bioremediation process and optimize the approximate parameters upto great accuracy. Copyright © 2017 Elsevier Inc. All rights reserved.

Assessment of a web-based Guided Self-Determination intervention for adults with type 2 diabetes in general practice: a study protocol

PubMed Central

Karlsen, Bjørg; Oftedal, Bjørg; Stangeland Lie, Silje; Rokne, Berit; Peyrot, Mark; Zoffmann, Vibeke; Graue, Marit

2016-01-01

Introduction Self-management is deemed the cornerstone in overall diabetes management. Web-based self-management interventions have potential to support adults with type 2 diabetes (T2DM) in managing their disease. Owing to somewhat ambiguous results of such interventions, interventions should be theory-based and incorporate well-defined counselling methods and techniques for behavioural change. This study is designed to assess the effectiveness of a theory-driven web-based Guided Self-Determination (GSD) intervention among adults with T2DM in general practice to improve diabetes self-management behaviours and glycosylated haemoglobin (HbA1c). Methods and analysis A complex intervention design based on the framework of the UK Medical Research Council is employed as a guide for developing the intervention, assessing its feasibility and evaluating its effectiveness. The study consists of three phases: (1) the modelling phase adapting the original GSD programme for adults with T2DM, using a qualitative design, (2) feasibility assessment of the adapted intervention on the web, employing qualitative and quantitative methods and (3) evaluating the effectiveness of the intervention on diabetes self-management behaviours and HbA1c, using a quasi-experimental design. The first phase, which is completed, and the second phase, which is underway, will provide important information about the development of the intervention and its acceptability, whereas the third phase will assess the effectiveness of this systematically developed intervention. Ethics and dissemination The Norwegian Regional Committee for Medical and Health Research Ethics (REK west number 2015/60) has approved the study design. Patients recruited in the different phases will fill out an informed consent form prior to inclusion and will be guaranteed anonymity and the right to withdraw from the study at any time. The results of the study will be published in peer-reviewed journals, electronically and in print, and presented at research conferences. Trial registration number: NCT02575599. PMID:27965253

The importance of design thinking in medical education.

PubMed

Badwan, Basil; Bothara, Roshit; Latijnhouwers, Mieke; Smithies, Alisdair; Sandars, John

2018-04-01

Design thinking provides a creative and innovate approach to solve a complex problem. The discover, define, develop and delivery phases of design thinking lead to the most effective solution and this approach can be widely applied in medical education, from technology intervention projects to curriculum development. Participants in design thinking acquire essential transferable life-long learning skills in dealing with uncertainty and collaborative team working.

Creating meaningful learning experiences: Understanding students' perspectives of engineering design

NASA Astrophysics Data System (ADS)

Aleong, Richard James Chung Mun

There is a societal need for design education to prepare holistic engineers with the knowledge, skills, and attitudes to innovate and compete globally. Design skills are paramount to the espoused values of higher education, as institutions of higher learning strive to develop in students the cognitive abilities of critical thinking, problem solving, and creativity. To meet these interests from industry and academia, it is important to advance the teaching and learning of engineering design. This research aims to understand how engineering students learn and think about design, as a way for engineering educators to optimize instructional practice and curriculum development. Qualitative research methodology was used to investigate the meaning that engineering students' ascribe to engineering design. The recruitment of participants and corresponding collection of data occurred in two phases using two different data collection techniques. The first phase involved the distribution of a one-time online questionnaire to all first year, third year, and fourth year undergraduate engineering students at three Canadian Universities. After the questionnaire, students were asked if they would be willing to participate in the second phase of data collection consisting of a personal interview. A total of ten students participated in interviews. Qualitative data analysis procedures were conducted on students' responses from the questionnaire and interviews. The data analysis process consisted of two phases: a descriptive phase to code and categorize the data, followed by an interpretative phase to generate further meaning and relationships. The research findings present a conceptual understanding of students' descriptions about engineering design, structured within two educational orientations: a learning studies orientation and a curriculum studies orientation. The learning studies orientation captured three themes of students' understanding of engineering design: awareness, relevance, and transfer. With this framework of student learning, engineering educators can enhance learning experiences by engaging all three levels of students' understanding. The curriculum studies orientation applied the three holistic elements of curriculum---subject matter, society, and the individual---to conceptualize design considerations for engineering curriculum and teaching practice. This research supports the characterization of students' learning experiences to help educators and students optimize their teaching and learning of design education.

Production of Hydrogen by Superadiabatic Decomposition of Hydrogen Sulfide - Final Technical Report for the Period June 1, 1999 - September 30, 2000

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rachid B. Slimane; Francis S. Lau; Javad Abbasian

2000-10-01

The objective of this program is to develop an economical process for hydrogen production, with no additional carbon dioxide emission, through the thermal decomposition of hydrogen sulfide (H{sub 2}S) in H{sub 2}S-rich waste streams to high-purity hydrogen and elemental sulfur. The novel feature of the process being developed is the superadiabatic combustion (SAC) of part of the H{sub 2}S in the waste stream to provide the thermal energy required for the decomposition reaction such that no additional energy is required. The program is divided into two phases. In Phase 1, detailed thermochemical and kinetic modeling of the SAC reactor withmore » H{sub 2}S-rich fuel gas and air/enriched air feeds is undertaken to evaluate the effects of operating conditions on exit gas products and conversion efficiency, and to identify key process parameters. Preliminary modeling results are used as a basis to conduct a thorough evaluation of SAC process design options, including reactor configuration, operating conditions, and productivity-product separation schemes, with respect to potential product yields, thermal efficiency, capital and operating costs, and reliability, ultimately leading to the preparation of a design package and cost estimate for a bench-scale reactor testing system to be assembled and tested in Phase 2 of the program. A detailed parametric testing plan was also developed for process design optimization and model verification in Phase 2. During Phase 2 of this program, IGT, UIC, and industry advisors UOP and BP Amoco will validate the SAC concept through construction of the bench-scale unit and parametric testing. The computer model developed in Phase 1 will be updated with the experimental data and used in future scale-up efforts. The process design will be refined and the cost estimate updated. Market survey and assessment will continue so that a commercial demonstration project can be identified.« less

Systematic Evaluation Program (SEP) at Rocky Flats Plant: An overview of practical management issues for evaluation of natural phenomena hazards

DOE Office of Scientific and Technical Information (OSTI.GOV)

Badwan, F.M.; Herring, K.S.

1993-08-01

Many of the buildings at the Rocky Flats Plant were designed and built before modern standards were developed, including standards for protection against extreme natural phenomenon such as tornadoes, earthquakes, and floods. The purpose of the SEP is to establish an integrated approach to assessing the design adequacy of specific high and moderate hazard Rocky Flats facilities from a safety perspective and to establish a basis for defining any needed facility improvements. The SEP is to be carried out in three Phases. In Phase 1, topics to be evaluated and an evaluation plan for each topic were developed. Any differencesmore » between Current Design Requirements (CDR) or acceptance criteria and the design of existing facilities, will be identified during Phase 2 and assessed using an integrated systematic approach during Phase 3. The integrated assessment performed during Phase 3 provides a process for evaluating the differences between existing facility design and CDRs so that decisions on corrective actions can be made on the basis of relative risk reduction and cost effectiveness. These efforts will ensure that a balanced and integrated level of safety is achieved for long-term operation of these buildings. Through appropriate selection of topics and identification of the structures, systems, and components to be evaluated, the SEP will address outstanding design issues related to the prevention and mitigation of design basis accidents, including those arising from natural phenomena. The objective of the SEP is not to bring these buildings into strict compliance with current requirements, but rather to ensure that an adequate level of safety is achieved in an economical fashion.« less

Commercial Art. Project Report Phase I with Research Findings.

ERIC Educational Resources Information Center

Brown, Ted; Sappe', Hoyt

This report provides results of Phase I of a project that researched the occupational area of commercial art, established appropriate committees, and conducted task verification. These results are intended to guide development of a program designed to train commercial artists. Section 1 contains general information: purpose of Phase I; description…

A Risk Management Framework to Characterize Black Swan Risks: A Case Study of Lightning Effects on Insensitive High Explosives

NASA Astrophysics Data System (ADS)

Sanders, Gary A.

Effective and efficient risk management processes include the use of high fidelity modeling and simulation during the concept exploration phase as part of the technology and risk assessment activities, with testing and evaluation tasks occurring in later design development phases. However, some safety requirements and design architectures may be dominated by the low probability/high consequence "Black Swan" vulnerabilities that require very early testing to characterize and efficiently mitigate. Failure to address these unique risks has led to catastrophic systems failures including the space shuttle Challenger, Deepwater Horizon, Fukushima nuclear reactor, and Katrina dike failures. Discovering and addressing these risks later in the design and development process can be very costly or even lead to project cancellation. This paper examines the need for risk management process adoption of early hazard phenomenology testing to inform the technical risk assessment, requirements definition and conceptual design. A case study of the lightning design vulnerability of the insensitive high explosives being used in construction, mining, demolition, and defense industries will be presented to examine the impact of this vulnerability testing during the concept exploration phase of the design effort. While these insensitive high explosives are far less sensitive to accidental initiation by fire, impact, friction or even electrical stimuli, their full range of sensitivities have not been characterized and ensuring safe engineering design and operations during events such as lightning storms requires vulnerability testing during the risk assessment phase.

Space transfer vehicle concepts and requirements study. Volume 1: Executive summary

NASA Technical Reports Server (NTRS)

Weber, Gary A.

1991-01-01

A description of the study in terms of background, objectives, and issues is provided. NASA is currently studying new initiatives of space exploration involving both piloted and unpiloted missions to destinations throughout the solar system. Many of these missions require substantial improvements in launch vehicle and upper stage capabilities. This study provides a focused examination of the Space Transfer Vehicles (STV) required to perform these missions using the emerging national launch vehicle definition, the Space Station Freedom (SSF) definition, and the latest mission scenario requirements. The study objectives are to define preferred STV concepts capable of accommodating future exploration missions in a cost-effective manner, determine the technology development (if any) required to perform these missions, and develop a decision database of various programmatic approaches for the development of the STV family of vehicles. Special emphasis was given to examining space basing (stationing reusable vehicles at a space station), examining the piloted lunar mission as a primary design mission, and restricting trade studies to the high-performance, near-term cryogenics (LO2/LH2) as vehicle propellant. The study progressed through three distinct 6-month phases. The first phase concentrated on supporting a NASA 3 month definition of exploration requirements (the '90-day study') and during this phase developed and optimized the space-based point-of-departure (POD) 2.5-stage lunar vehicle. The second phase developed a broad decision database of 95 different vehicle options and transportation architectures. The final phase chose the three most cost-effective architectures and developed point designs to carry to the end of the study. These reference vehicle designs are mutually exclusive and correspond to different national choices about launch vehicles and in-space reusability. There is, however, potential for evolution between concepts.

Advanced Stirling receiver development program, phase 1

NASA Technical Reports Server (NTRS)

Lurio, Charles A.

1990-01-01

Critical technology experiments were designed and developed to evaluate the Stirling cavity heat pipe receiver for a space solar power system. Theoretical criteria were applied to the design of a module for containing energy storage phase change material while avoiding thermal ratcheting. Zero-g drop tower tests, without phase change, were conducted to affirm that the bubble location required to avoid ratcheting could be achieved without the use of container materials that are wetted by the phase change material. A full scale module was fabricated, but not tested. A fabrication method was successfully developed for the sodium evaporator dome, with a sintered screen wick, to be used as the focal point for the receiver. Crushing of the screen during hydroforming was substantially reduced over the results of other researchers by using wax impregnation. Superheating of the sodium in the wick under average flux conditions is expected to be under 10K. A 2000K furnace which will simulate solar flux conditions for testing the evaporator dome was successfully built and tested.

Development of the simulation system {open_quotes}IMPACT{close_quotes} for analysis of nuclear power plant severe accidents

DOE Office of Scientific and Technical Information (OSTI.GOV)

Naitoh, Masanori; Ujita, Hiroshi; Nagumo, Hiroichi

1997-07-01

The Nuclear Power Engineering Corporation (NUPEC) has initiated a long-term program to develop the simulation system {open_quotes}IMPACT{close_quotes} for analysis of hypothetical severe accidents in nuclear power plants. IMPACT employs advanced methods of physical modeling and numerical computation, and can simulate a wide spectrum of senarios ranging from normal operation to hypothetical, beyond-design-basis-accident events. Designed as a large-scale system of interconnected, hierarchical modules, IMPACT`s distinguishing features include mechanistic models based on first principles and high speed simulation on parallel processing computers. The present plan is a ten-year program starting from 1993, consisting of the initial one-year of preparatory work followed bymore » three technical phases: Phase-1 for development of a prototype system; Phase-2 for completion of the simulation system, incorporating new achievements from basic studies; and Phase-3 for refinement through extensive verification and validation against test results and available real plant data.« less

Human Engineering of Space Vehicle Displays and Controls

NASA Technical Reports Server (NTRS)

Whitmore, Mihriban; Holden, Kritina L.; Boyer, Jennifer; Stephens, John-Paul; Ezer, Neta; Sandor, Aniko

2010-01-01

Proper attention to the integration of the human needs in the vehicle displays and controls design process creates a safe and productive environment for crew. Although this integration is critical for all phases of flight, for crew interfaces that are used during dynamic phases (e.g., ascent and entry), the integration is particularly important because of demanding environmental conditions. This panel addresses the process of how human engineering involvement ensures that human-system integration occurs early in the design and development process and continues throughout the lifecycle of a vehicle. This process includes the development of requirements and quantitative metrics to measure design success, research on fundamental design questions, human-in-the-loop evaluations, and iterative design. Processes and results from research on displays and controls; the creation and validation of usability, workload, and consistency metrics; and the design and evaluation of crew interfaces for NASA's Crew Exploration Vehicle are used as case studies.

Instrumentation progress at the Giant Magellan Telescope project

NASA Astrophysics Data System (ADS)

Jacoby, George H.; Bernstein, R.; Bouchez, A.; Colless, M.; Crane, Jeff; DePoy, D.; Espeland, B.; Hare, Tyson; Jaffe, D.; Lawrence, J.; Marshall, J.; McGregor, P.; Shectman, Stephen; Sharp, R.; Szentgyorgyi, A.; Uomoto, Alan; Walls, B.

2016-08-01

Instrument development for the 24m Giant Magellan Telescope (GMT) is described: current activities, progress, status, and schedule. One instrument team has completed its preliminary design and is currently beginning its final design (GCLEF, an optical 350-950 nm, high-resolution and precision radial velocity echelle spectrograph). A second instrument team is in its conceptual design phase (GMACS, an optical 350-950 nm, medium resolution, 6-10 arcmin field, multi-object spectrograph). A third instrument team is midway through its preliminary design phase (GMTIFS, a near-IR YJHK diffraction-limited imager/integral-field-spectrograph), focused on risk reduction prototyping and design optimization. A fourth instrument team is currently fabricating the 5 silicon immersion gratings needed to begin its preliminary design phase (GMTNIRS, a simultaneous JHKLM high-resolution, AO-fed, echelle spectrograph). And, another instrument team is focusing on technical development and prototyping (MANIFEST, a facility robotic, multifiber feed, with a 20 arcmin field of view). In addition, a medium-field (6 arcmin, 0.06 arcsec/pix) optical imager will support telescope and AO commissioning activities, and will excel at narrow-band imaging. In the spirit of advancing synergies with other groups, the challenges of running an ELT instrument program and opportunities for cross-ELT collaborations are discussed.

Using pattern enumeration to accelerate process development and ramp yield

NASA Astrophysics Data System (ADS)

Zhuang, Linda; Pang, Jenny; Xu, Jessy; Tsai, Mengfeng; Wang, Amy; Zhang, Yifan; Sweis, Jason; Lai, Ya-Chieh; Ding, Hua

2016-03-01

During a new technology node process setup phase, foundries do not initially have enough product chip designs to conduct exhaustive process development. Different operational teams use manually designed simple test keys to set up their process flows and recipes. When the very first version of the design rule manual (DRM) is ready, foundries enter the process development phase where new experiment design data is manually created based on these design rules. However, these IP/test keys contain very uniform or simple design structures. This kind of design normally does not contain critical design structures or process unfriendly design patterns that pass design rule checks but are found to be less manufacturable. It is desired to have a method to generate exhaustive test patterns allowed by design rules at development stage to verify the gap of design rule and process. This paper presents a novel method of how to generate test key patterns which contain known problematic patterns as well as any constructs which designers could possibly draw based on current design rules. The enumerated test key patterns will contain the most critical design structures which are allowed by any particular design rule. A layout profiling method is used to do design chip analysis in order to find potential weak points on new incoming products so fab can take preemptive action to avoid yield loss. It can be achieved by comparing different products and leveraging the knowledge learned from previous manufactured chips to find possible yield detractors.

Assessing the feasibility, cost, and utility of developing models of human performance in aviation

NASA Technical Reports Server (NTRS)

Stillwell, William

1990-01-01

The purpose of the effort outlined in this briefing was to determine whether models exist or can be developed that can be used to address aviation automation issues. A multidisciplinary team has been assembled to undertake this effort, including experts in human performance, team/crew, and aviation system modeling, and aviation data used as input to such models. The project consists of two phases, a requirements assessment phase that is designed to determine the feasibility and utility of alternative modeling efforts, and a model development and evaluation phase that will seek to implement the plan (if a feasible cost effective development effort is found) that results from the first phase. Viewgraphs are given.

Development of wave and surge atlas for the design and protection of coastal bridges in south Louisiana - phase 2, tech summary.

DOT National Transportation Integrated Search

2016-08-01

The first phase of this project, documented in LTRC Final Report 528, developed meteorological/ : oceanographic (met/ocean) data for the 100-year storm return period in south Louisiana and presented the : data in a GIS platform known as the Wave and ...

Development of Interactive Learning Media on Kinetic Gas Theory at SMAN 2 Takalar

NASA Astrophysics Data System (ADS)

Yanti, M.; Ihsan, N.; Subaer

2017-02-01

Learning media is the one of the most factor in supporting successfully in the learning process. The purpose of this interactive media is preparing students to improve skills in laboratory practice without need for assistance and are not bound by time and place. The subject of this study was 30 students grade XI IPA SMAN 2 Takalar. This paper discuss about the development of learning media based in theory of gas kinetic. This media designed to assist students in learning independently. This media made using four software, they are Microsoft word, Snagit Editor, Macromedia Flash Player and Lectora. This media are interactive, dynamic and could support the users desires to learn and understand course of gas theory. The development produce followed the four D models. Consisted of definition phase, design phase, development phase and disseminate phase. The results showed 1) the media were valid and reliable, 2) learning tools as well as hardcopy and softcopy which links to website 3) activity learners above 80% and 4) according to the test results, the concept of comprehension of student was improved than before given interactive media.

Space Station ECLSS Integration Analysis

NASA Technical Reports Server (NTRS)

1993-01-01

The Space Station Environmental Control and Life Support System (ECLSS) contract with NASA MSFC covered the time frame from 9 May 1985 to 31 Dec. 1992. The contract roughly covered the period of Space Station Freedom (SSF) development from early Phase B through Phase C/D Critical Design Review (CDR). During this time, McDonnell Douglas Aerospace-Huntsville (formerly McDonnell Douglas Space Systems Company) performed an analytical support role to MSFC for the development of analytical math models and engineering trade studies related to the design of the ECLSS for the SSF.

Advanced Life Support Water Recycling Technologies Case Studies: Vapor Phase Catalytic Ammonia Removal and Direct Osmotic Concentration

NASA Technical Reports Server (NTRS)

Flynn, Michael

2004-01-01

Design for microgravity has traditionally not been well integrated early on into the development of advanced life support (ALS) technologies. NASA currently has a many ALS technologies that are currently being developed to high technology readiness levels but have not been formally evaluated for microgravity compatibility. Two examples of such technologies are the Vapor Phase Catalytic Ammonia Removal Technology and the Direct Osmotic Concentration Technology. This presentation will cover the design of theses two systems and will identify potential microgravity issues.

Recovery Act: High-Efficiency, Wideband Three-Phase Rectifiers and Adaptive Rectifier Management for Telecomm Central Office and Large Data Center Applications

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mark A. Johnson

2012-06-29

Lineage Power and Verizon teamed up to address a DOE funding opportunity focused on improving the power conversion chain in telecommunications facilities and data centers. The project had three significant elements: the design and development of high efficiency and high power three-phase rectifiers by Lineage Power, design and development of software to optimize overall plant energy efficiency by Lineage Power, and a field trial in active Verizon telecommunications facilities where energy consumption was measured before and after efficiency upgrades.

Design Tools for Cost-Effective Implementation of Planetary Protection Requirements

NASA Technical Reports Server (NTRS)

Hamlin, Louise; Belz, Andrea; Evans, Michael; Kastner, Jason; Satter, Celeste; Spry, Andy

2006-01-01

Since the Viking missions to Mars in the 1970s, accounting for the costs associated with planetary protection implementation has not been done systematically during early project formulation phases, leading to unanticipated costs during subsequent implementation phases of flight projects. The simultaneous development of more stringent planetary protection requirements, resulting from new knowledge about the limits of life on Earth, together with current plans to conduct life-detection experiments on a number of different solar system target bodies motivates a systematic approach to integrating planetary protection requirements and mission design. A current development effort at NASA's Jet Propulsion Laboratory is aimed at integrating planetary protection requirements more fully into the early phases of mission architecture formulation and at developing tools to more rigorously predict associated cost and schedule impacts of architecture options chosen to meet planetary protection requirements.

Evaluating a Professional Development Framework to Empower Chemistry Teachers to Design Context-Based Education

ERIC Educational Resources Information Center

Stolk, Machiel Johan; Bulte, Astrid; De Jong, Onno; Pilot, Albert

2012-01-01

Even experienced chemistry teachers require professional development when they are encouraged to become actively engaged in the design of new context-based education. This study briefly describes the development of a framework consisting of goals, learning phases, strategies and instructional functions, and how the framework was translated into a…

Design and implementation of ergonomic performance measurement system at a steel plant in India.

PubMed

Ray, Pradip Kumar; Tewari, V K

2012-01-01

Management of Tata Steel, the largest steel making company of India in the private sector, felt the need to develop a framework to determine the levels of ergonomic performance at its different workplaces. The objectives of the study are manifold: to identify and characterize the ergonomic variables for a given worksystem with regard to work efficiency, operator safety, and working conditions, to design a comprehensive Ergonomic Performance Indicator (EPI) for quantitative determination of the ergonomic status and maturity of a given worksystem. The study team of IIT Kharagpur consists of three faculty members and the management of Tata Steel formed a team of eleven members for implementation of EPI model. In order to design and develop the EPI model with total participation and understanding of the concerned personnel of Tata Steel, a three-phase action plan for the project was prepared. The project consists of three phases: preparation and data collection, detailed structuring and validation of EPI model. Identification of ergonomic performance factors, development of interaction matrix, design of assessment tool, and testing and validation of assessment tool (EPI) in varied situations are the major steps in these phases. The case study discusses in detail the EPI model and its applications.

Phase I Final Scientific Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lu, Xijia; Fetvedt, Jeremy; Dimmig, Walker

This Final Scientific Report addresses the accomplishments achieved during Phase I of DE- FE0023985, Coal Syngas Combustor Development for Supercritical CO 2 Power Cycles. The primary objective of the project was to develop a coal syngas-fueled combustor design for use with high-pressure, high-temperature, oxy-fuel, supercritical CO 2 power cycles, with particular focus given to the conditions required by the Allam Cycle. The primary goals, from the Statement of Project Objectives, were to develop: (1) a conceptual design of a syngas-fueled combustor-turbine block for a 300MWe high-pressure, oxy-fuel, sCO2 power plant; (2) the preliminary design of a 5MWt test combustor; andmore » (3) the definition of a combustor test program. Accomplishments for each of these goals are discussed in this report.« less

Design, fabrication, testing, and delivery of improved beam steering devices

NASA Technical Reports Server (NTRS)

1973-01-01

The development, manufacture, and testing of an optical steerer intended for use in spaceborne optical radar systems are described. Included are design principles and design modifications made to harden the device against launch and space environments, the quality program and procedures developed to insure consistent product quality throughout the manufacturing phase, and engineering qualification model testing and evaluation. The delivered hardware design is considered conditionally qualified pending action on further recommended design modifications.

Long-life 3-axis satellite attitude sensing, phase 1

NASA Technical Reports Server (NTRS)

Arild, Tor

1987-01-01

The purpose was to investigate the feasibility of new, moderate-cost, high reliability navigation sensors for high-altitude satellites, using stellar sources to obviate the use of gyroscopic devices. The primary investigation focused on the need for developing a star tracker model to replace an old star tracker which is still needed for current probe and satellite programs. One innovative element of the proposed star tracker was the design, development, and testing of technology components related to a phase scrambler plate. The purpose of the phase scrambler plate is to convert the impulse response of the optical system from a point image to a uniformly bright, square, angularly large, in-focus image of the star source. A collimated star source was built and tested. A breadboard star tracker with an 8 x 8 degree field of view was designed and built. It was tested in normal quad-cell mode (without the phase scrambler plate) and with the phase scrambler plate. Although the phase scrambler plate was crudely made, the performance of the star tracker breadboard was greatly improved using the phase scrambler plate, instead of system defocus. If further developed, the phase scrambler plate may be added as a low-cost retroconversion to any objective lens to greatly improve quad-cell or CCD array tracking; applications include star trackers, laser metrology, laser machining optics, and surveying instrumentation.

Modified Standard Penetration Test–based Drilled Shaft Design Method for Weak Rocks (Phase 2 Study)

DOT National Transportation Integrated Search

2017-12-15

In this project, Illinois-specific design procedures were developed for drilled shafts founded in weak shale or rock. In particular, a modified standard penetration test was developed and verified to characterize the in situ condition of weak shales ...

Bid opening report : Federal-aid highway construction contracts : first six months 2001

DOT National Transportation Integrated Search

2000-04-01

This research update provides general human factors design information relevant to the early phases of in-vehicle icon development and design. It reflects a subset of the results to date of a Federal Highway Administration project to develop a set of...

Crossbar H-mode drift-tube linac design with alternative phase focusing for muon linac

NASA Astrophysics Data System (ADS)

Otani, M.; Futatsukawa, K.; Hasegawa, K.; Kitamura, R.; Kondo, Y.; Kurennoy, S.

2017-07-01

We have developed a Crossbar H-mode (CH) drift-tube linac (DTL) design with an alternative phase focusing (APF) scheme for a muon linac, in order to measure the anomalous magnetic moment and electric dipole moment (EDM) of muons at the Japan Proton Accelerator Research Complex (J-PARC). The CH-DTL accelerates muons from β = v/c = 0.08 to 0.28 at an operational frequency of 324 MHz. The design and results are described in this paper.

Usability in product design--the importance and need for systematic assessment models in product development--Usa-Design Model (U-D) ©.

PubMed

Merino, Giselle Schmidt Alves Díaz; Teixeira, Clarissa Stefani; Schoenardie, Rodrigo Petry; Merino, Eugenio Andrés Diáz; Gontijo, Leila Amaral

2012-01-01

In product design, human factors are considered as an element of differentiation given that today's consumer demands are increasing. Safety, wellbeing, satisfaction, health, effectiveness, efficiency, and other aspects must be effectively incorporated into the product development process. This work proposes a usability assessment model that can be incorporated as an assessment tool. The methodological approach is settled in two stages. First a literature review focus specifically on usability and developing user-centred products. After this, a model of usability named Usa-Design (U-D©) is presented. Consisted of four phases: understanding the use context, pre-preliminary usability assessment (efficiency/effectiveness/satisfaction); assessment of usability principles and results, U-D© features are modular and flexible, allowing principles used in Phase 3 to be changed according to the needs and scenario of each situation. With qualitative/quantitative measurement scales of easy understanding and application, the model results are viable and applicable throughout all the product development process.

Automated solar panel assembly line

NASA Technical Reports Server (NTRS)

Somberg, H.

1981-01-01

The initial stage of the automated solar panel assembly line program was devoted to concept development and proof of approach through simple experimental verification. In this phase, laboratory bench models were built to demonstrate and verify concepts. Following this phase was machine design and integration of the various machine elements. The third phase was machine assembly and debugging. In this phase, the various elements were operated as a unit and modifications were made as required. The final stage of development was the demonstration of the equipment in a pilot production operation.

Implementation of an Expert System for Instructional Design: Phase 2. Design Document & Technical Report.

ERIC Educational Resources Information Center

Merrill, M. David; Li, Zhongmin

The purpose of this project was to develop a prototype expert instructional design system (ID Expert) which would demonstrate the feasibility of a consultation system for use by inexperienced instructional designers. The prototype gathers information from the designer and then makes recommendations for instructional design decisions. The output of…

Optimal design variable considerations in the use of phase change materials in indirect evaporative cooling

NASA Astrophysics Data System (ADS)

Chilakapaty, Ankit Paul

The demand for sustainable, energy efficient and cost effective heating and cooling solutions is exponentially increasing with the rapid advancement of computation and information technology. Use of latent heat storage materials also known as phase change materials (PCMs) for load leveling is an innovative solution to the data center cooling demands. These materials are commercially available in the form of microcapsules dispersed in water, referred to as the microencapsulated phase change slurries and have higher heat capacity than water. The composition and physical properties of phase change slurries play significant role in energy efficiency of the cooling systems designed implementing these PCM slurries. Objective of this project is to study the effect of PCM particle size, shape and volumetric concentration on overall heat transfer potential of the cooling systems designed with PCM slurries as the heat transfer fluid (HTF). In this study uniform volume heat source model is developed for the simulation of heat transfer potential using phase change materials in the form of bulk temperature difference in a fully developed flow through a circular duct. Results indicate the heat transfer potential increases with PCM volumetric concentration with gradually diminishing returns. Also, spherical PCM particles offer greater heat transfer potential when compared to cylindrical particles. Results of this project will aid in efficient design of cooling systems based on PCM slurries.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Flanigan, Tom; Pybus, Craig; Roy, Sonya

This report summarizes the results of the Pre-Front End Engineering Design (pre-FEED) phase of a proposed advanced oxy-combustion power generation plant to repower the existing 200 MWe Unit 4 at Ameren Energy Resources’ (AER) Meredosia Power Plant. AER has formed an alliance with Air Liquide Process and Construction, Inc. (ALPC) and Babcock & Wilcox Power Generation Group (B&W PGG) for the design, construction, and testing of the facility, and has contracted with URS Corporation (URS) for preliminary design and Owner’s engineering services. The Project employs oxy-combustion technology – combustion of coal with nearly pure oxygen and recycled flue gas (insteadmore » of air) – to capture approximately 90% of the flue gas CO2 for transport and sequestration by another Project. Plant capacity and configuration has been developed based on the B&W PGG-ALPC cool recycle process firing high-sulfur bituminous coal fuel, assuming baseload plant operation to maximize existing steam turbine capability, with limited consideration for plant redundancy and performance optimization in order to keep plant costs as low as practical. Activities and preliminary results from the pre-FEED phase addressed in this report include the following: Overall plant thermal performance; Equipment sizing and system configuration; Plant operation and control philosophy; Plant emissions and effluents; CO 2 production and recovery characteristics; Project cost estimate and economic evaluation; Integrated project engineering and construction schedule; Project risk and opportunity assessment; Development of Project permitting strategy and requirements During the Phase 2 of the Project, additional design details will be developed and the Phase 1 work products updated to support actual construction and operation of the facility in Phase 3. Additional information will be provided early in Phase 2 to support Ameren-Environmental in finalizing the appropriate permitting strategies and permit applications. Additional performance and reliability enhancements will also be evaluated in Phase 2 to try to improve overall project economics.« less

Microstructural Developments Leading to New Advanced High Strength Sheet Steels: A Historical Assessment of Critical Metallographic Observations

DOE Office of Scientific and Technical Information (OSTI.GOV)

Matlock, David K; Thomas, Larrin S; Taylor, Mark D

In the past 30+ years significant advancements have been made in the development of higher strength sheet steels with improved combinations of strength and ductility that have enabled important product improvements leading to safer, lighter weight, and more fuel efficient automobiles and in other applications. Properties of the primarily low carbon, low alloy steels are derived through careful control of time-temperature processing histories designed to produce multiphase ferritic based microstructures that include martensite and other constituents including retained austenite. The basis for these developments stems from the early work on dual-phase steels which was the subject of much interest. Inmore » response to industry needs, dual-phase steels have evolved as a unique class of advanced high strength sheet steels (AHSS) in which the thermal and mechanical processing histories have been specifically designed to produce constituent combinations for the purpose of simultaneously controlling strength and deformation behavior, i.e. stress-strain curve shapes. Improvements continue as enhanced dual-phase steels have recently been produced with finer microstructures, higher strengths, and better overall formability. Today, dual phase steels are the primary AHSS products used in vehicle manufacture, and several companies have indicated that the steels will remain as important design materials well into the future. In this presentation, fundamental results from the early work on dual-phase steels will be reviewed and assessed in light of recent steel developments. Specific contributions from industry/university cooperative research leading to product improvements will be highlighted. The historical perspective provided in the evolution of dual-phase steels represents a case-study that provides important framework and lessons to be incorporated in next generation AHSS products.« less

SBIR Phase II Final Report: Low cost Autonomous NMR and Multi-sensor Soil Monitoring Instrument

DOE Office of Scientific and Technical Information (OSTI.GOV)

Walsh, David O.

In this 32-month SBIR Phase 2 program, Vista Clara designed, assembled and successfully tested four new NMR instruments for soil moisture measurement and monitoring: An enhanced performance man-portable Dart NMR logging probe and control unit for rapid, mobile measurement in core holes and 2” PVC access wells; A prototype 4-level Dart NMR monitoring probe and prototype multi-sensor soil monitoring control unit for long-term unattended monitoring of soil moisture and other measurements in-situ; A non-invasive 1m x 1m Discus NMR soil moisture sensor with surface based magnet/coil array for rapid measurement of soil moisture in the top 50 cm of themore » subsurface; A non-invasive, ultra-lightweight Earth’s field surface NMR instrument for non-invasive measurement and mapping of soil moisture in the top 3 meters of the subsurface. The Phase 2 research and development achieved most, but not all of our technical objectives. The single-coil Dart in-situ sensor and control unit were fully developed, demonstrated and successfully commercialized within the Phase 2 period of performance. The multi-level version of the Dart probe was designed, assembled and demonstrated in Phase 2, but its final assembly and testing were delayed until close to the end of the Phase 2 performance period, which limited our opportunities for demonstration in field settings. Likewise, the multi-sensor version of the Dart control unit was designed and assembled, but not in time for it to be deployed for any long-term monitoring demonstrations. The prototype ultra-lightweight surface NMR instrument was developed and demonstrated, and this result will be carried forward into the development of a new flexible surface NMR instrument and commercial product in 2018.« less

Power management and distribution system for a More-Electric Aircraft (MADMEL) -- Program status

DOE Office of Scientific and Technical Information (OSTI.GOV)

Maldonado, M.A.; Shah, N.M.; Cleek, K.J.

1995-12-31

A number of technology breakthroughs in recent years have rekindled the concept of a more-electric aircraft. High-power solid-state switching devices, electrohydrostatic actuators (EHAs), electromechanical actuators (EMAs), and high-power generators are just a few examples of component developments that have made dramatic improvements in properties such as weight, size, power, and cost. However, these components cannot be applied piecemeal. A complete, and somewhat revolutionary, system design approach is needed to exploit the benefits that a more-electric aircraft can provide. A five-phase Power Management and Distribution System for a More-Electric Aircraft (MADMEL) program was awarded by the Air Force to the Northrop/Grumman,more » Military Aircraft Division team in September 1991. The objective of the program is to design, develop, and demonstrate an advanced electrical power generation and distribution system for a more-electric aircraft (MEA). The MEA emphasizes the use of electrical power in place of hydraulics, pneumatic, and mechanical power to optimize the performance and life cycle cost of the aircraft. This paper presents an overview of the MADMEL program and a top-level summary of the program results, development and testing of major components to date. In Phase 1 and Phase 2 studies, the electrical load requirements were established and the electrical power system architecture was defined for both near-term (NT-year 1996) and far-term (FT-year 2003) MEA application. The detailed design and specification for the electrical power system (EPS), its interface with the Vehicle Management System, and the test set-up were developed under the recently completed Phase 3. The subsystem level hardware fabrication and testing will be performed under the on-going Phase 4 activities. The overall system level integration and testing will be performed in Phase 5.« less

Development of a dome Fresnel lens/gallium arsenide photovoltaic concentrator for space applications

NASA Technical Reports Server (NTRS)

O'Neill, Mark J.; Piszczor, Michael F.

1987-01-01

A novel photovoltaic concentrator system is currently being developed. Phase I of the program, completed in late 1986, produced a conceptual design for the concentrator system, including an array weight and performance estimates based on optical, electrical, and thermal analyses. Phase II of the program, just underway, concerns the fabrication and testing of prototype concentrator panels of the design. The concentrator system uses dome Fresnel lenses for optical concentration; gallium arsenide concentrator cells for power generation; prismatic cell covers to eliminate gridline obscuration losses; a backplane radiator for heat rejection; and a honeycomb structure for the deployable panel assembly. The conceptual design of the system, its anticipated performance, and its estimated weight are reported.

Implementation of a production Ada project: The GRODY study

NASA Technical Reports Server (NTRS)

Godfrey, Sara; Brophy, Carolyn Elizabeth

1989-01-01

The use of the Ada language and design methodologies that encourage full use of its capabilities have a strong impact on all phases of the software development project life cycle. At the National Aeronautics and Space Administration/Goddard Space Flight Center (NASA/GSFC), the Software Engineering Laboratory (SEL) conducted an experiment in parallel development of two flight dynamics systems in FORTRAN and Ada. The differences observed during the implementation, unit testing, and integration phases of the two projects are described and the lessons learned during the implementation phase of the Ada development are outlined. Included are recommendations for future Ada development projects.

Labyrinth Seal Analysis. Volume 3. Analytical and Experimental Development of a Design Model for Labyrinth Seals

DTIC Science & Technology

1986-01-01

the information that has been determined experimentally. The Labyrinth Seal Analysis program was, therefore, directed to the develop - ment of an...labyrinth seal performance, the program included the development of an improved empirical design model to pro- j. .,’ vide the calculation of the flow... program . * Phase I was directed to the analytical development of both an *analysis* model and an improvwd empirical *design" model. Supporting rig tests

Prevention of Posttraumatic Contractures with Ketotifen (PERK)

DTIC Science & Technology

2017-10-01

opportunity to design a Phase III RCT on the use of ketotifen in post -traumatic joint contractures. The goal is to design and develop the infrastructure to...Research (CIHR) for the Phase III RCT. 2. KEYWORDS Post -traumatic contractures, elbow fractures, randomized clinical trial, multicenter, ketotifen...application to use ketotifen in post -traumatic joint contracture prevention was submitted to the Division of Pulmonary, Allergy, and Rheumatology

Burn Resuscitation Decision Support System (BRDSS)

DTIC Science & Technology

2013-09-01

effective for burn care in the deployed and en route care settings. In this period, we completed Human Factors studies, hardware testing , software design ... designated U.S. Army Institute of Surgical Research (USAISR) clinical team. Phase 1 System Requirements and Software Development Arcos will draft a...airworthiness testing . The hardware finalists will be sent to U.S. Army Aeromedical Research Laboratory (USAARL) for critical airworthiness testing . Phase

Development of a dual-field heteropoplar power converter

NASA Technical Reports Server (NTRS)

Eisenhaure, D. B.; Johnson, B.; Bliamptis, T.; St. George, E.

1981-01-01

The design and testing of a 400 watt, dual phase, dual rotor, field modulated inductor alternator is described. The system is designed for use as a flywheel to ac utility line or flywheel to dc bus (electric vehicle) power converter. The machine is unique in that it uses dual rotors and separately controlled fields to produce output current and voltage which are in phase with each other. Having the voltage and current in phase allows the power electronics to be made of simple low cost components. Based on analytical predictions and experimental results, development of a complete 22 kilowatt (30 Hp) power conversion system is recommended. This system would include power electronics and controls and would replace the inductor alternator with an improved electromagnetic conversion system.

Synchronization algorithm for three-phase voltages of an inverter and a grid

NASA Astrophysics Data System (ADS)

Nos, O. V.

2017-07-01

This paper presents the results of designing a joint phase-locked loop for adjusting the phase shifts (speed) and Euclidean norm of three-phase voltages of an inverter to the same grid parameters. The design can be used, in particular, to match the potentials of two parallel-connected power sources for the fundamental harmonic at the moments of switching the stator windings of an induction AC motor from a converter to a centralized power-supply system and back. Technical implementation of the developed synchronization algorithm will significantly reduce the inductance of the current-balancing reactor and exclude emergency operation modes in the electric motor power circuit.

Phase Response Design of Recursive All-Pass Digital Filters Using a Modified PSO Algorithm

PubMed Central

2015-01-01

This paper develops a new design scheme for the phase response of an all-pass recursive digital filter. A variant of particle swarm optimization (PSO) algorithm will be utilized for solving this kind of filter design problem. It is here called the modified PSO (MPSO) algorithm in which another adjusting factor is more introduced in the velocity updating formula of the algorithm in order to improve the searching ability. In the proposed method, all of the designed filter coefficients are firstly collected to be a parameter vector and this vector is regarded as a particle of the algorithm. The MPSO with a modified velocity formula will force all particles into moving toward the optimal or near optimal solution by minimizing some defined objective function of the optimization problem. To show the effectiveness of the proposed method, two different kinds of linear phase response design examples are illustrated and the general PSO algorithm is compared as well. The obtained results show that the MPSO is superior to the general PSO for the phase response design of digital recursive all-pass filter. PMID:26366168

The practical application of adaptive study design in early phase clinical trials: a retrospective analysis of time savings.

PubMed

Lorch, U; Berelowitz, K; Ozen, C; Naseem, A; Akuffo, E; Taubel, J

2012-05-01

The interest in adaptive study design is evident from the growing amount of clinical research employing this model in the mid to later stages of medicines development. Little has been published on the practical application and merits of adaptive study design in early phase clinical research. This paper describes a retrospective analysis performed on a sample of 29 industry lead adaptive early phase studies commencing between 1 January 2006 and 31 December 2010 in a clinical trials unit in London, England. All studies containing at least one adaptive feature in the original protocol were included in the analysis. The scope of the analysis was to assess whether the use of adaptive study designs provided tangible benefits over the use of conventional study designs using time savings as the main measure. We conclude that the use of adaptive study design saves time in early phase research programs. This is achieved by abolishing the need for substantial amendments or by mitigating their impact on timelines and by using adaptive scheduling efficiencies.

Design and analysis of low-loss linear analog phase modulator for deep space spacecraft X-band transponder (DST) application

NASA Technical Reports Server (NTRS)

Mysoor, Narayan R.; Mueller, Robert O.

1991-01-01

This paper summarizes the design concepts, analyses, and the development of an X-band transponder low-loss linear phase modulator for deep space spacecraft applications. A single section breadboard circulator-coupled reflection phase modulator has been analyzed, fabricated, and evaluated. Two- and three-cascaded sections have been modeled and simulations performed to provide an X-band DST phase modulator with +/- 2.5 radians of peak phase deviation to accommodate down-link signal modulation with composite telemetry data and ranging with a deviation linearity tolerance +/- 8 percent and insertion loss of less than 10 +/- 0.5 dB. A two-section phase modulator using constant gamma hyperabrupt varactors and an efficient modulator driver circuit was breadboarded. The measured results satisfy the DST phase modulator requirements, and excellent agreement with the predicted results.

Evolving Reliability and Maintainability Allocations for NASA Ground Systems

NASA Technical Reports Server (NTRS)

Munoz, Gisela; Toon, Jamie; Toon, Troy; Adams, Timothy C.; Miranda, David J.

2016-01-01

This paper describes the methodology that was developed to allocate reliability and maintainability requirements for the NASA Ground Systems Development and Operations (GSDO) program's subsystems. As systems progressed through their design life cycle and hardware data became available, it became necessary to reexamine the previously derived allocations. Allocating is an iterative process; as systems moved beyond their conceptual and preliminary design phases this provided an opportunity for the reliability engineering team to reevaluate allocations based on updated designs and maintainability characteristics of the components. Trade-offs in reliability and maintainability were essential to ensuring the integrity of the reliability and maintainability analysis. This paper will discuss the value of modifying reliability and maintainability allocations made for the GSDO subsystems as the program nears the end of its design phase.

Lessons learned in the transition to Ada from FORTRAN at NASA/Goddard

NASA Technical Reports Server (NTRS)

Brophy, Carolyn Elizabeth

1989-01-01

Two dynamics satellite simulators are developed from the same requirements, one in Ada and the other in FORTRAN. The purpose of the research was to find out how well the prescriptive Ada development model worked to develop the Ada simulator. The FORTRAN simulator development, as well as past FORTRAN developments, provided a baseline for comparison. Since this was the first simulator developed, the prescriptive Ada development model had many similarities to the usual FORTRAN development model. However, it was modified to include longer design and shorter testing phases, which is generally expected with Ada developments. One result was that the percentage of time the Ada project spent in the various development activities was very similar to the percentage of time spent in these activities when doing a FORTRAN project. Another finding was the difficulty the Ada team had with unit testing as well as with integration. It was realized that adding additional steps to the design phase, such as an abstract data type analysis, and certain guidelines to the implementation phase, such as to use primarily library units and nest sparingly, would have made development easier. These are among the recommendations made to be incorporated in a new Ada development model next time.

Some design considerations for a synthetic aperture optical telescope array

NASA Astrophysics Data System (ADS)

Scott, P. W.

1984-01-01

Several design considerations inherent in the configuration of phased array transmission of multiwavelength laser beams are discussed. Attention is focused on the U.S.A.F. phased array (PHASAR) demonstration project, where problems have been encountered in dividing the beam(s), controlling the optical path differences between subapertures, and expanding individual beams.A piston-driven path length adjustment mechanism has been selected, along with an active control system and proven components for stability maintenance. The necessity of developing broadband, high reflectivity low phase shift coatings for the system mirrors is stressed.

Absolute Stability Analysis of a Phase Plane Controlled Spacecraft

NASA Technical Reports Server (NTRS)

Jang, Jiann-Woei; Plummer, Michael; Bedrossian, Nazareth; Hall, Charles; Jackson, Mark; Spanos, Pol

2010-01-01

Many aerospace attitude control systems utilize phase plane control schemes that include nonlinear elements such as dead zone and ideal relay. To evaluate phase plane control robustness, stability margin prediction methods must be developed. Absolute stability is extended to predict stability margins and to define an abort condition. A constrained optimization approach is also used to design flex filters for roll control. The design goal is to optimize vehicle tracking performance while maintaining adequate stability margins. Absolute stability is shown to provide satisfactory stability constraints for the optimization.

Towards Risk Based Design for NASA's Missions

NASA Technical Reports Server (NTRS)

Tumer, Irem Y.; Barrientos, Francesca; Meshkat, Leila

2004-01-01

This paper describes the concept of Risk Based Design in the context of NASA s low volume, high cost missions. The concept of accounting for risk in the design lifecycle has been discussed and proposed under several research topics, including reliability, risk analysis, optimization, uncertainty, decision-based design, and robust design. This work aims to identify and develop methods to enable and automate a means to characterize and optimize risk, and use risk as a tradeable resource to make robust and reliable decisions, in the context of the uncertain and ambiguous stage of early conceptual design. This paper first presents a survey of the related topics explored in the design research community as they relate to risk based design. Then, a summary of the topics from the NASA-led Risk Colloquium is presented, followed by current efforts within NASA to account for risk in early design. Finally, a list of "risk elements", identified for early-phase conceptual design at NASA, is presented. The purpose is to lay the foundation and develop a roadmap for future work and collaborations for research to eliminate and mitigate these risk elements in early phase design.

Single-Crystal Sapphire Optical Fiber Sensor Instrumentation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pickrell, Gary; Scott, Brian; Wang, Anbo

2013-12-31

This report summarizes technical progress on the program “Single-Crystal Sapphire Optical Fiber Sensor Instrumentation,” funded by the National Energy Technology Laboratory of the U.S. Department of Energy, and performed by the Center for Photonics Technology of the Bradley Department of Electrical and Computer Engineering at Virginia Tech. This project was completed in three phases, each with a separate focus. Phase I of the program, from October 1999 to April 2002, was devoted to development of sensing schema for use in high temperature, harsh environments. Different sensing designs were proposed and tested in the laboratory. Phase II of the program, frommore » April 2002 to April 2009, focused on bringing the sensor technologies, which had already been successfully demonstrated in the laboratory, to a level where the sensors could be deployed in harsh industrial environments and eventually become commercially viable through a series of field tests. Also, a new sensing scheme was developed and tested with numerous advantages over all previous ones in Phase II. Phase III of the program, September 2009 to December 2013, focused on development of the new sensing scheme for field testing in conjunction with materials engineering of the improved sensor packaging lifetimes. In Phase I, three different sensing principles were studied: sapphire air-gap extrinsic Fabry-Perot sensors; intensity-based polarimetric sensors; and broadband polarimetric sensors. Black body radiation tests and corrosion tests were also performed in this phase. The outcome of the first phase of this program was the selection of broadband polarimetric differential interferometry (BPDI) for further prototype instrumentation development. This approach is based on the measurement of the optical path difference (OPD) between two orthogonally polarized light beams in a single-crystal sapphire disk. At the beginning of Phase II, in June 2004, the BPDI sensor was tested at the Wabash River coal gasifier facility in Terre Haute, Indiana. Due to business conditions at industrial partner and several logistical problems, this field test was not successful. An alternative high-temperature sensing system using sapphire wafer-based extrinsic Fabry-Perot interferometry was then developed as a significant improvement over the BPDI solution. From June 2006 to June 2008, three consecutive field tests were performed with the new sapphire wafer sensors at the TECO coal gasifier in Tampa, Florida. One of the sensors survived in the industrial coal gasifier for 7 months, over which time the existing thermocouples were replaced twice. The outcome of these TECO field tests suggests that the sapphire wafer sensor has very good potential to be commercialized. However packaging and sensor protection issues need additional development. During Phase III, several major improvements in the design and fabrication process of the sensor have been achieved through experiments and theoretical analysis. Studies on the property of the key components in the sensor head, including the sapphire fiber and sapphire wafer, were also conducted, for a better understanding of the sensor behavior. A final design based on all knowledge and experience has been developed, free of any issues encountered during the entire research. Sensors with this design performed well as expected in lab long-term tests, and were deployed in the sensing probe of the final coal-gasifier field test. Sensor packaging and protection was improved through materials engineering through testing of packaging designs in two blank probe packaging tests at Eastman Chemical in Kingsport, TN. Performance analysis of the blank probe packaging resulted in improve package designs culminating in a 3rd generation probe packaging utilized for the full field test of the sapphire optical sensor and materials designed sensor packaging.« less

A Multidisciplinary Approach to Decommissioning Offshore Wells Using Stakeholder Engagement, Risk Identification, and the United Nations Sustainable Development Goals

NASA Astrophysics Data System (ADS)

Battalora, L.; Prasad, M.

2017-12-01

Context/PurposeThe typical oil and gas project lifecycle includes acquisition, exploration, drilling, production, and decommissioning phases. The oil and gas industry (Industry) has become proactive in identifying and mitigating health, safety, security, environment, and social responsibility risks during these phases as well as designing for sustainable development. With many fields reaching the end stages of the lifecycle, Industry is faced with the challenge of identifying and evaluating risks in the decommissioning phase. The level of challenge is increased when planning for the decommissioning of offshore wells. This paper describes tools that can be applied in the multidisciplinary design of the decommissioning program including use of the United Nations Sustainable Development Goals (SDGs). MethodsStakeholder engagement is key to a successful project. Typical stakeholders in an oil and gas project include the community, regulatory agencies, federal, state, and local governments, private investors, academia, and non-governmental organizations. Before engagement begins, stakeholders must be identified as well as their level of influence in the project. Relationships between stakeholders are "mapped" providing a better understanding of priorities and areas of concentration. Project risks are identified and ranked according to likelihood and impact. Mitigations are matched to risks. Sustainable development is implemented through acknowledgement of societal, economic, and environmental impacts in engineering design. InterpretationRecently, the United Nations Development Programme (UNDP), the International Finance Corporation (IFC) and IPIECA, the global oil and gas industry association for environmental and social issues, partnered to develop the publication, Mapping the oil and gas industry to the Sustainable Development Goals: An Atlas. SDGs have been linked to Industry operations and can serve as a guide for the offshore decommissioning phase ConclusionA multidisciplinary approach using stakeholder engagement and risk identification tools and the United Nations Sustainable Development Goals is recommended for designing the decommissioning program of offshore wells. This recommendation also applies to onshore decommissioning programs.

A high order approach to flight software development and testing

NASA Technical Reports Server (NTRS)

Steinbacher, J.

1981-01-01

The use of a software development facility is discussed as a means of producing a reliable and maintainable ECS software system, and as a means of providing efficient use of the ECS hardware test facility. Principles applied to software design are given, including modularity, abstraction, hiding, and uniformity. The general objectives of each phase of the software life cycle are also given, including testing, maintenance, code development, and requirement specifications. Software development facility tools are summarized, and tool deficiencies recognized in the code development and testing phases are considered. Due to limited lab resources, the functional simulation capabilities may be indispensable in the testing phase.

Configuration-shape-size optimization of space structures by material redistribution

NASA Technical Reports Server (NTRS)

Vandenbelt, D. N.; Crivelli, L. A.; Felippa, C. A.

1993-01-01

This project investigates the configuration-shape-size optimization (CSSO) of orbiting and planetary space structures. The project embodies three phases. In the first one the material-removal CSSO method introduced by Kikuchi and Bendsoe (KB) is further developed to gain understanding of finite element homogenization techniques as well as associated constrained optimization algorithms that must carry along a very large number (thousands) of design variables. In the CSSO-KB method an optimal structure is 'carved out' of a design domain initially filled with finite elements, by allowing perforations (microholes) to develop, grow and merge. The second phase involves 'materialization' of space structures from the void, thus reversing the carving process. The third phase involves analysis of these structures for construction and operational constraints, with emphasis in packaging and deployment. The present paper describes progress in selected areas of the first project phase and the start of the second one.

Integrating nutrition and early child-development interventions among infants and preschoolers in rural India.

PubMed

Fernandez-Rao, Sylvia; Hurley, Kristen M; Nair, Krishnapillai Madhavan; Balakrishna, Nagalla; Radhakrishna, Kankipati V; Ravinder, Punjal; Tilton, Nicholas; Harding, Kimberly B; Reinhart, Greg A; Black, Maureen M

2014-01-01

This article describes the development, design, and implementation of an integrated randomized double-masked placebo-controlled trial (Project Grow Smart) that examines how home/preschool fortification with multiple micronutrient powder (MNP) combined with an early child-development intervention affects child development, growth, and micronutrient status among infants and preschoolers in rural India. The 1-year trial has an infant phase (enrollment age: 6-12 months) and a preschool phase (enrollment age: 36-48 months). Infants are individually randomized into one of four groups: placebo, placebo plus early learning, MNP alone, and MNP plus early learning (integrated intervention), conducted through home visits. The preschool phase is a cluster-randomized trial conducted in Anganwadi centers (AWCs), government-run preschools sponsored by the Integrated Child Development System of India. AWCs are randomized into MNP or placebo, with the MNP or placebo mixed into the children's food. The evaluation examines whether the effects of the MNP intervention vary by the quality of the early learning opportunities and communication within the AWCs. Study outcomes include child development, growth, and micronutrient status. Lessons learned during the development, design, and implementation of the integrated trial can be used to guide large-scale policy and programs designed to promote the developmental, educational, and economic potential of children in developing countries. © 2013 New York Academy of Sciences.

Modular space station phase B extension integrated ground operations

NASA Technical Reports Server (NTRS)

Selegue, D. F.

1971-01-01

Requirements for development test, manufacturing, facilities, GSE, training, logistics support, and launch operations are described. The prime integrating requirement is the early establishment of a common data base and its use throughout the design, development, and operational life of the station. The common data base is defined, and the concept of its use is presented. Development requirements for the station modules and subsystems are outlined along with a master development phasing chart.

Stud Walls With Continuous Exterior Insulation for Factory Built Housing: New York, New York (Fact Sheet), NREL (National Renewable Energy Laboratory)

DOE Office of Scientific and Technical Information (OSTI.GOV)

None, None

The Advanced Envelope Research effort will provide factory homebuilders with high performance, cost-effective alternative envelope designs. In the near term, these technologies will play a central role in meeting stringent energy code requirements. For manufactured homes, the thermal requirements, last updated by statute in 1994, will move up to the more rigorous IECC 2012 levels in 2013, the requirements of which are consistent with site built and modular housing. This places added urgency on identifying envelope technologies that the industry can implement in the short timeframe. The primary goal of this research is to develop wall designs that meet themore » thermal requirements based on 2012 IECC standards. Given the affordable nature of manufactured homes, impact on first cost is a major consideration in developing the new envelope technologies. This work is part of a four-phase, multi-year effort. Phase 1 identified seven envelope technologies and provided a preliminary assessment of three selected methods for building high performance wall systems. Phase 2 focused on the development of viable product designs, manufacturing strategies, addressing code and structural issues, and cost analysis of the three selected options. An industry advisory committee helped critique and select the most viable solution to move further in the research - stud walls with continuous exterior insulation. Phase 3, the subject of the current report, focused on the design development of the selected wall concept and explored variations on the use of exterior foam insulation. The scope also included material selection, manufacturing and cost analysis, and prototyping and testing.« less

Technology Solutions Case Study: Stud Walls with Continuous Exterior Insulation for Factory Built Housing

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

The Advanced Envelope Research effort will provide factory homebuilders with high performance, cost-effective alternative envelope designs. In the near term, these technologies will play a central role in meeting stringent energy code requirements. For manufactured homes, the thermal requirements, last updated by statute in 1994, will move up to the more rigorous IECC 2012 levels in 2013, the requirements of which are consistent with site built and modular housing. This places added urgency on identifying envelope technologies that the industry can implement in the short timeframe. The primary goal of this research is to develop wall designs that meet themore » thermal requirements based on 2012 IECC standards. Given the affordable nature of manufactured homes, impact on first cost is a major consideration in developing the new envelope technologies. This work is part of a four-phase, multi-year effort. Phase 1 identified seven envelope technologies and provided a preliminary assessment of three selected methods for building high performance wall systems. Phase 2 focused on the development of viable product designs, manufacturing strategies, addressing code and structural issues, and cost analysis of the three selected options. An industry advisory committee helped critique and select the most viable solution to move further in the research — stud walls with continuous exterior insulation. Phase 3, the subject of the current report, focused on the design development of the selected wall concept and explored variations on the use of exterior foam insulation. The scope also included material selection, manufacturing and cost analysis, and prototyping and testing.« less

Sheet Metal Contract. Project Report Phase I with Research Findings.

ERIC Educational Resources Information Center

Kirkpatrick, Thomas; Sappe', Hoyt

This report provides results of Phase I of a project that researched the occupational area of sheet metal, established appropriate committees, and conducted task verification. These results are intended to guide development of a program designed to train sheet metal workers. Section 1 contains general information: purpose of Phase I; description…

78 FR 9051 - Agency Information Collection Activities; Proposed Collection; Comment Request

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-07

... Information Technology Phase 1.'' In accordance with the Paperwork Reduction Act, 44 U.S.C. 3501-3521, AHRQ... Technology Phase 1 This project is the first phase in AHRQ's effort toward the development of a health information technology (HIT) enabled tool designed to aid adolescents and young adults with sickle cell...

Feasibility of MHD submarine propulsion

DOE Office of Scientific and Technical Information (OSTI.GOV)

Doss, E.D.; Sikes, W.C.

1992-09-01

This report describes the work performed during Phase 1 and Phase 2 of the collaborative research program established between Argonne National Laboratory (ANL) and Newport News Shipbuilding and Dry Dock Company (NNS). Phase I of the program focused on the development of computer models for Magnetohydrodynamic (MHD) propulsion. Phase 2 focused on the experimental validation of the thruster performance models and the identification, through testing, of any phenomena which may impact the attractiveness of this propulsion system for shipboard applications. The report discusses in detail the work performed in Phase 2 of the program. In Phase 2, a two Teslamore » test facility was designed, built, and operated. The facility test loop, its components, and their design are presented. The test matrix and its rationale are discussed. Representative experimental results of the test program are presented, and are compared to computer model predictions. In general, the results of the tests and their comparison with the predictions indicate that thephenomena affecting the performance of MHD seawater thrusters are well understood and can be accurately predicted with the developed thruster computer models.« less

Prediction of forces and moments for hypersonic flight vehicle control effectors

NASA Technical Reports Server (NTRS)

Maughmer, Mark D.; Long, Lyle N.; Guilmette, Neal; Pagano, Peter

1993-01-01

This research project includes three distinct phases. For completeness, all three phases of the work are briefly described in this report. The goal was to develop methods of predicting flight control forces and moments for hypersonic vehicles which could be used in a preliminary design environment. The first phase included a preliminary assessment of subsonic/supersonic panel methods and hypersonic local flow inclination methods for such predictions. While these findings clearly indicated the usefulness of such methods for conceptual design activities, deficiencies exist in some areas. Thus, a second phase of research was conducted in which a better understanding was sought for the reasons behind the successes and failures of the methods considered, particularly for the cases at hypersonic Mach numbers. This second phase involved using computational fluid dynamics methods to examine the flow fields in detail. Through these detailed predictions, the deficiencies in the simple surface inclination methods were determined. In the third phase of this work, an improvement to the surface inclination methods was developed. This used a novel method for including viscous effects by modifying the geometry to include the viscous/shock layer.

New Approach to Concept Feasibility and Design Studies for Astrophysics Missions

NASA Technical Reports Server (NTRS)

Deutsch, M. J.; McLaughlin, W.; Nichols, J.

1998-01-01

JPL has assembled a team of multidisciplinary experts with corporate knowledge of space mission and instrument development. The advanced Concept Design Team, known as Team X, provides interactive design trades including cost as a design parameter, and advanced visualization for pre-Phase A Studies.

Sand-control completion design, installation, and performance in high-rate gas wells

DOE Office of Scientific and Technical Information (OSTI.GOV)

Burton, R.C.; Boggan, S.A.

1998-09-01

The Jupiter fields consist of a number of separate Rotliegendes gas reservoirs located approximately 90 miles off the Lincolnshire coast of the UK. The fields that make up Jupiter are Ganymede, Calisto, Europa, Sinope, and Thebe. Originally discovered in 1970, initial appraisal wells indicated poor reservoir properties and low deliverabilities. Development was postponed until a reappraisal of the area in the 1990`s indicated significant upside potential. The initial phase of the Jupiter development plan called for development of Ganymede and Calisto fields, with subsequent phases tying in Europa and Thebe. Initial development planning indicated a need for high field deliverabilitymore » at low capital cost to meet economic targets. A small number of high-rate-potential wells were to be used to deplete the reservoir. Ganymede would be developed by use of a 10-slot platform and Calisto would be developed subsea and tied back to the Ganymede platform. The paper discusses the reservoir, formation assessment, productivity design, drilling design, screen installation, and completion performance.« less

75 FR 69680 - National Institute of Child Health and Human Development; Revision to Proposed Collection...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-11-15

... study design elements for a prospective, national longitudinal study of child health and development. In combination, the substudies encompassed by the Vanguard phase will be used to inform the design of the Main... that are to be used in the design of the NCS Main Study. The Vanguard Study begins prior to the NCS...

Development of a Test for an Experimental Research Program in Creative Problem Solving. Final Report.

ERIC Educational Resources Information Center

Miles, David T.

The purpose of this first phase of a continuing research program was the development of a test of creative problem solving in general design. A design class of 186 members was divided into an experimental and control group; a non-design control group (an educational psychology class) of 45 was also tested. Multivariate interpretation of creative…

Phase 1 Development Report for the SESSA Toolkit

DTIC Science & Technology

2014-09-01

data acquisition, data management, and data analysis. SESSA was designed to meet forensic crime scene needs as defined by the DoD’s Military Criminal...on the design , functional attributes, algorithm development, system architecture, and software programming include: Robert Knowlton, Brad Melton...Building Restoration Operations Optimization Model (BROOM). BROOM (Knowlton et al., 2012) was designed for consequence management activities (e.g

Microwave power transmitting phased array antenna research project

NASA Technical Reports Server (NTRS)

Dickinson, R. M.

1978-01-01

An initial design study and the development results of an S band RF power transmitting phased array antenna experiment system are presented. The array was to be designed, constructed and instrumented to permit wireless power transmission technology evaluation measurements. The planned measurements were to provide data relative to the achievable performance in the state of the art of flexible surface, retrodirective arrays, as a step in technically evaluating the satellite power system concept for importing to earth, via microwave beams, the nearly continuous solar power available in geosynchronous orbit. Details of the microwave power transmitting phased array design, instrumentation approaches, system block diagrams, and measured component and breadboard characteristics achieved are presented.

Defining Support Requirements During Conceptual Design of Reusable Launch Vehicles

NASA Technical Reports Server (NTRS)

Morris, W. D.; White, N. H.; Davis, W. T.; Ebeling, C. E.

1995-01-01

Current methods for defining the operational support requirements of new systems are data intensive and require significant design information. Methods are being developed to aid in the analysis process of defining support requirements for new launch vehicles during their conceptual design phase that work with the level of information available during this phase. These methods will provide support assessments based on the vehicle design and the operating scenarios. The results can be used both to define expected support requirements for new launch vehicle designs and to help evaluate the benefits of using new technologies. This paper describes the models, their current status, and provides examples of their use.

MMIC linear-phase and digital modulators for deep space spacecraft X-band transponder applications

NASA Technical Reports Server (NTRS)

Mysoor, Narayan R.; Ali, Fazal

1991-01-01

The design concepts, analyses, and development of GaAs monolithic microwave integrated circuit (MMIC) linear-phase and digital modulators for the next generation of space-borne communications systems are summarized. The design approach uses a compact lumped element quadrature hybrid and Metal Semiconductor Field Effect Transistors (MESFET)-varactors to provide low loss and well-controlled phase performance for deep space transponder (DST) applications. The measured results of the MESFET-diode show a capacitance range of 2:1 under reverse bias, and a Q of 38 at 10 GHz. Three cascaded sections of hybrid-coupled reflection phase shifters were modeled and simulations performed to provide an X-band (8415 +/- 50 MHz) DST phase modulator with +/- 2.5 radians of peak phase deviation. The modulator will accommodate downlink signal modulation with composite telemetry and ranging data, with a deviation linearity tolerance of +/- 8 percent and insertion loss of less than 8 +/- 0.5 dB. The MMIC digital modulator is designed to provide greater than 10 Mb/s of bi-phase modulation at X-band.

Trade-off results and preliminary designs of Near-Term Hybrid Vehicles

NASA Technical Reports Server (NTRS)

Sandberg, J. J.

1980-01-01

Phase I of the Near-Term Hybrid Vehicle Program involved the development of preliminary designs of electric/heat engine hybrid passenger vehicles. The preliminary designs were developed on the basis of mission analysis, performance specification, and design trade-off studies conducted independently by four contractors. THe resulting designs involve parallel hybrid (heat engine/electric) propulsion systems with significant variation in component selection, power train layout, and control strategy. Each of the four designs is projected by its developer as having the potential to substitute electrical energy for 40% to 70% of the petroleum fuel consumed annually by its conventional counterpart.

Design and development of high frequency matrix phased-array ultrasonic probes

NASA Astrophysics Data System (ADS)

Na, Jeong K.; Spencer, Roger L.

2012-05-01

High frequency matrix phased-array (MPA) probes have been designed and developed for more accurate and repeatable assessment of weld conditions of thin sheet metals commonly used in the auto industry. Unlike the line focused ultrasonic beam generated by a linear phased-array (LPA) probe, a MPA probe can form a circular shaped focused beam in addition to the typical beam steering capabilities of phased-array probes. A CIVA based modeling and simulation method has been used to design the probes in terms of various probe parameters such as number of elements, element size, overall dimensions, frequency etc. Challenges associated with the thicknesses of thin sheet metals have been resolved by optimizing these probe design parameters. A further improvement made on the design of the MPA probe proved that a three-dimensionally shaped matrix element can provide a better performing probe at a much lower probe manufacturing cost by reducing the total number of elements and lowering the operational frequency. This three dimensional probe naturally matches to the indentation shape of the weld on the thin sheet metals and hence a wider inspection area with the same level of spatial resolution obtained by a twodimensional flat MPA probe operating at a higher frequency. The two aspects, a wider inspection area and a lower probe manufacturing cost, make this three-dimensional MPA sensor more attractive to auto manufacturers demanding a quantitative nondestructive inspection method.

Railroad classification yard design methodology study Elkhart Yard Rehabilitation : a case study

DOT National Transportation Integrated Search

1980-02-01

This interim report documents the application of a railroad classification : yard design methodology to CONRAIL's Elkhart Yard Rehabilitation. This : case study effort represents Phase 2 of a larger effort to develop a yard : design methodology, and ...

Integrated low emissions cleanup system for direct coal-fueled turbines

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lippert, T.E.; Newby, R.A.; Alvin, M.A.

1992-01-01

The Westinghouse Electric Corporation, Science Technology Center (W-STC) is developing an Integrated Low Emissions Cleanup (ILEC) concept for high-temperature gas cleaning to meet environmental standards, as well as to economical gas turbine life. The ILEC concept simultaneously controls sulfur, particulate, and alkali contaminants in high-pressure fuel gases or combustion gases at temperatures up to 1850[degrees]F for advanced power generation systems (PFBC, APFBC, IGCC, DCF7). The objective of this program is to demonstrate, at a bench scale, the conceptual, technical feasibility of the REC concept. The ELEC development program has a 3 phase structure: Phase 1 - laboratory-scale testing; phase 2more » - bench-scale equipment; design and fabrication; and phase 3 - bench-scale testing. Phase 1 laboratory testing has been completed. In Phase 1, entrained sulfur and alkali sorbent kinetics were measured and evaluated, and commercial-scale performance was projected. Related cold flow model testing has shown that gas-particle contacting within the ceramic barrier filter vessel will provide a good reactor environment. The Phase 1 test results and the commercial evaluation conducted in the Phase 1 program support the bench-scale facility testing to be performed in Phase 3. Phase 2 is nearing completion with the design and assembly of a modified, bench-scale test facility to demonstrate the technical feasibility of the ILEC features. This feasibility testing will be conducted in Phase 3.« less

Safety Guided Design Based on Stamp/STPA for Manned Vehicle in Concept Design Phase

NASA Astrophysics Data System (ADS)

Ujiie, Ryo; Katahira, Masafumi; Miyamoto, Yuko; Umeda, Hiroki; Leveson, Nancy; Hoshino, Nobuyuki

2013-09-01

In manned vehicles, such as the Soyuz and the Space Shuttle, the crew and computer system cooperate to succeed in returning to the earth. While computers increase the functionality of system, they also increase the complexity of the interaction between the controllers (human and computer) and the target dynamics. In some cases, the complexity can produce a serious accident. To prevent such losses, traditional hazard analysis such as FTA has been applied to system development, however it can be used after creating a detailed system because it focuses on detailed component failures. As a result, it's more difficult to eliminate hazard cause early in the process when it is most feasible.STAMP/STPA is a new hazard analysis that can be applied from the early development phase, with the analysis being refined as more detailed decisions are made. In essence, the analysis and design decisions are intertwined and go hand-in-hand. We have applied STAMP/STPA to a concept design of a new JAXA manned vehicle and tried safety guided design of the vehicle. As a result of this trial, it has been shown that STAMP/STPA can be accepted easily by system engineers and the design has been made more sophisticated from a safety viewpoint. The result also shows that the consequences of human errors on system safety can be analysed in the early development phase and the system designed to prevent them. Finally, the paper will discuss an effective way to harmonize this safety guided design approach with system engineering process based on the result of this experience in this project.

Design, fabrication, test, qualification and price analysis of third generation design solar cell modules. Part 1: Intermediate load module

NASA Technical Reports Server (NTRS)

Bottenberg, W. R.

1981-01-01

The updated program plan and narrative reflects the design and development work done and progress made in establishing a viable design for these modules. Design alterations from the preproduction plan are discussed based on experience gained during the preproduction phase of the program.

Conception preliminaire de disques de turbine axiale pour moteurs d'aeronefs

NASA Astrophysics Data System (ADS)

Ouellet, Yannick

The preliminary design phase of a turbine rotor has an important impact on the architecture of a new engine definition, as it sets the technical orientation right from start and provides a good estimate of product performance, weight and cost. In addition, the execution speed at this preliminary phase has become critical into capturing business opportunities. Improving upfront accuracy also alleviates downstream detailed design work and therefore reduces overall product development cycle time. This preliminary phase contains elements slowing down its process, including low interoperability of currently used systems, incompatibility of software and ineffective management of data. In order to overcome these barriers, we have developed the first module of a new Design and Analysis (D&A) platform for the rotor disc. This complete platform ensures integration of different tools processing in batch mode, and is driven from a single graphical user interface. The platform developed has been linked with different optimization methods (algorithms, configuration) in order to automate the disc design and propose best practices for rotor structural optimization. This methodology allowed reduction in design cycle time and improvement of performance. It was applied on two reference P&WC axial discs. The platform's architecture was also used in the development of reference charts to better understand disc performance within given design space. Four high pressure rotor discs of P&WC turbofan and turboprop engines were used to generate the technical charts and understand the effect of various parameters. The new tools supporting disc D&A, combined with the optimization process and reference charts, has proven to be profitable in terms of component performance and engineering effort inputs.

Designing eHealth that Matters via a Multidisciplinary Requirements Development Approach.

PubMed

Van Velsen, Lex; Wentzel, Jobke; Van Gemert-Pijnen, Julia Ewc

2013-06-24

Requirements development is a crucial part of eHealth design. It entails all the activities devoted to requirements identification, the communication of requirements to other developers, and their evaluation. Currently, a requirements development approach geared towards the specifics of the eHealth domain is lacking. This is likely to result in a mismatch between the developed technology and end user characteristics, physical surroundings, and the organizational context of use. It also makes it hard to judge the quality of eHealth design, since it makes it difficult to gear evaluations of eHealth to the main goals it is supposed to serve. In order to facilitate the creation of eHealth that matters, we present a practical, multidisciplinary requirements development approach which is embedded in a holistic design approach for eHealth (the Center for eHealth Research roadmap) that incorporates both human-centered design and business modeling. Our requirements development approach consists of five phases. In the first, preparatory, phase the project team is composed and the overall goal(s) of the eHealth intervention are decided upon. Second, primary end users and other stakeholders are identified by means of audience segmentation techniques and our stakeholder identification method. Third, the designated context of use is mapped and end users are profiled by means of requirements elicitation methods (eg, interviews, focus groups, or observations). Fourth, stakeholder values and eHealth intervention requirements are distilled from data transcripts, which leads to phase five, in which requirements are communicated to other developers using a requirements notation template we developed specifically for the context of eHealth technologies. The end result of our requirements development approach for eHealth interventions is a design document which includes functional and non-functional requirements, a list of stakeholder values, and end user profiles in the form of personas (fictitious end users, representative of a primary end user group). The requirements development approach presented in this article enables eHealth developers to apply a systematic and multi-disciplinary approach towards the creation of requirements. The cooperation between health, engineering, and social sciences creates a situation in which a mismatch between design, end users, and the organizational context can be avoided. Furthermore, we suggest to evaluate eHealth on a feature-specific level in order to learn exactly why such a technology does or does not live up to its expectations.

Designing for sustained adoption: A model of developing educational innovations for successful propagation

NASA Astrophysics Data System (ADS)

Khatri, Raina; Henderson, Charles; Cole, Renée; Froyd, Jeffrey E.; Friedrichsen, Debra; Stanford, Courtney

2016-06-01

[This paper is part of the Focused Collection on Preparing and Supporting University Physics Educators.] The physics education research community has produced a wealth of knowledge about effective teaching and learning of college level physics. Based on this knowledge, many research-proven instructional strategies and teaching materials have been developed and are currently available to instructors. Unfortunately, these intensive research and development activities have failed to influence the teaching practices of many physics instructors. This paper describes interim results of a larger study to develop a model of designing materials for successful propagation. The larger study includes three phases, the first two of which are reported here. The goal of the first phase was to characterize typical propagation practices of education developers, using data from a survey of 1284 National Science Foundation (NSF) principal investigators and focus group data from eight disciplinary groups of NSF program directors. The goal of the second phase was to develop an understanding of successful practice by studying three instructional strategies that have been well propagated. The result of the first two phases is a tentative model of designing for successful propagation, which will be further validated in the third phase through purposeful sampling of additional well-propagated instructional strategies along with typical education development projects. We found that interaction with potential adopters was one of the key missing ingredients in typical education development activities. Education developers often develop a polished product before getting feedback, rely on mass-market communication channels for dissemination, and do not plan for supporting adopters during implementation. The tentative model resulting from this study identifies three key propagation activities: interactive development, interactive dissemination, and support of adopters. Interactive development uses significant feedback from potential adopters to develop a strong product suitable for use in many settings. Interactive dissemination uses personal interactions to reach and motivate potential users. Support of adopters is missing from typical propagation practice and is important to reduce the burden of implementation and increases the likelihood of successful adoption.

Integrated modeling tool for performance engineering of complex computer systems

NASA Technical Reports Server (NTRS)

Wright, Gary; Ball, Duane; Hoyt, Susan; Steele, Oscar

1989-01-01

This report summarizes Advanced System Technologies' accomplishments on the Phase 2 SBIR contract NAS7-995. The technical objectives of the report are: (1) to develop an evaluation version of a graphical, integrated modeling language according to the specification resulting from the Phase 2 research; and (2) to determine the degree to which the language meets its objectives by evaluating ease of use, utility of two sets of performance predictions, and the power of the language constructs. The technical approach followed to meet these objectives was to design, develop, and test an evaluation prototype of a graphical, performance prediction tool. The utility of the prototype was then evaluated by applying it to a variety of test cases found in the literature and in AST case histories. Numerous models were constructed and successfully tested. The major conclusion of this Phase 2 SBIR research and development effort is that complex, real-time computer systems can be specified in a non-procedural manner using combinations of icons, windows, menus, and dialogs. Such a specification technique provides an interface that system designers and architects find natural and easy to use. In addition, PEDESTAL's multiview approach provides system engineers with the capability to perform the trade-offs necessary to produce a design that meets timing performance requirements. Sample system designs analyzed during the development effort showed that models could be constructed in a fraction of the time required by non-visual system design capture tools.

Constellation Program (CxP) Crew Exploration Vehicle (CEV) Project Integrated Landing System

NASA Technical Reports Server (NTRS)

Baker, John D.; Yuchnovicz, Daniel E.; Eisenman, David J.; Peer, Scott G.; Fasanella, Edward L.; Lawrence, Charles

2009-01-01

Crew Exploration Vehicle (CEV) Chief Engineer requested a risk comparison of the Integrated Landing System design developed by NASA and the design developed by Contractor- referred to as the LM 604 baseline. Based on the results of this risk comparison, the CEV Chief engineer requested that the NESC evaluate identified risks and develop strategies for their reduction or mitigation. The assessment progressed in two phases. A brief Phase I analysis was performed by the Water versus Land-Landing Team to compare the CEV Integrated Landing System proposed by the Contractor against the NASA TS-LRS001 baseline with respect to risk. A phase II effort examined the areas of critical importance to the overall landing risk, evaluating risk to the crew and to the CEV Crew Module (CM) during a nominal land-landing. The findings of the assessment are contained in this report.

Using School-Level Interviews to Develop a Multisite PE Intervention Program

PubMed Central

Moe, Stacey G.; Pickrel, Julie; McKenzie, Thomas L.; Strikmiller, Patricia K.; Coombs, Derek; Murrie, Dale

2008-01-01

The Trial of Activity for Adolescent Girls (TAAG) is a randomized, multicenter field trial in middle schools that aims to reduce the decline of physical activity in adolescent girls. To inform the development of the TAAG intervention, two phases of formative research are conducted to gain information on school structure and environment and on the conduct of physical education classes. Principals and designated staff at 64 eligible middle schools were interviewed using the School Survey during Phase 1. The following year (Phase 2), physical education department heads of the 36 schools selected into TAAG were interviewed. Responses were examined to design a standardized, multicomponent physical activity intervention for six regions of the United States. This article describes the contribution of formative research to the development of the physical education intervention component and summarizes the alignment of current school policies and practices with national and state standards. PMID:16397159

Enhancing treatment fidelity in psychotherapy research: novel approach to measure the components of cognitive behavioural therapy for relapse prevention in first-episode psychosis.

PubMed

Alvarez-Jimenez, Mario; Wade, Darryl; Cotton, Sue; Gee, Donna; Pearce, Tracey; Crisp, Kingsley; McGorry, Patrick D; Gleeson, John F

2008-12-01

Establishing treatment fidelity is one of the most important aspects of psychotherapy research. Treatment fidelity refers to the methodological strategies used to examine and enhance the reliability and validity of psychotherapy. This study sought to develop and evaluate a measure specifically designed to assess fidelity to the different therapeutic components (i.e. therapy phases) of the individual intervention of a psychotherapy clinical trial (the EPISODE II trial). A representative sample of sessions stratified by therapy phase was assessed using a specifically developed fidelity measure (Relapse Prevention Therapy-Fidelity Scale, RPT-FS). Each RPT-FS subscale was designed to include a different component/phase of therapy and its major therapeutic ingredients. The measure was found to be reliable and had good internal consistency. The RPT-FS discriminated, almost perfectly, between therapy phases. The analysis of the therapeutic strategies implemented during the intervention indicated that treatment fidelity was good throughout therapy phases. While therapists primarily engaged in interventions from the appropriate therapeutic phase, flexibility in therapy was evident. This study described the development of a brief, reliable and internally consistent measure to determine both treatment fidelity and the therapy components implemented throughout the intervention. This methodology can be potentially useful to determine those components related to therapeutic change.

Feasibility of MHD submarine propulsion. Phase II, MHD propulsion: Testing in a two Tesla test facility

DOE Office of Scientific and Technical Information (OSTI.GOV)

Doss, E.D.; Sikes, W.C.

1992-09-01

This report describes the work performed during Phase 1 and Phase 2 of the collaborative research program established between Argonne National Laboratory (ANL) and Newport News Shipbuilding and Dry Dock Company (NNS). Phase I of the program focused on the development of computer models for Magnetohydrodynamic (MHD) propulsion. Phase 2 focused on the experimental validation of the thruster performance models and the identification, through testing, of any phenomena which may impact the attractiveness of this propulsion system for shipboard applications. The report discusses in detail the work performed in Phase 2 of the program. In Phase 2, a two Teslamore » test facility was designed, built, and operated. The facility test loop, its components, and their design are presented. The test matrix and its rationale are discussed. Representative experimental results of the test program are presented, and are compared to computer model predictions. In general, the results of the tests and their comparison with the predictions indicate that thephenomena affecting the performance of MHD seawater thrusters are well understood and can be accurately predicted with the developed thruster computer models.« less

Modular space station, phase B extension. Information management advanced development. Volume 2: Communications terminal breadboard

NASA Technical Reports Server (NTRS)

Gerber, C. R.

1972-01-01

The design and development of the communications terminal breadboard for the modular space station are discussed. The subjects presented are: (1) history of communications terminal breadboard, (2) requirements analysis, (3) technology goals in terminal design, and (4) communications terminal board integration tests.

Demonstration of enhanced human service transportation models: phase 1 - system development and design : the purchase area regional travel management coordination center (TMCC).

DOT National Transportation Integrated Search

2009-03-23

This report provides a comprehensive review of the policy, operational, and : technical design and development of the Purchase Area Transportation Management Coordination Center (TMCC) for : western Kentucky. The Purchase Area TMCC will facilitate si...

High-efficiency aperiodic two-dimensional high-contrast-grating hologram

NASA Astrophysics Data System (ADS)

Qiao, Pengfei; Zhu, Li; Chang-Hasnain, Connie J.

2016-03-01

High efficiency phase holograms are designed and implemented using aperiodic two-dimensional (2D) high-contrast gratings (HCGs). With our design algorithm and an in-house developed rigorous coupled-wave analysis (RCWA) package for periodic 2D HCGs, the structural parameters are obtained to achieve a full 360-degree phase-tuning range of the reflected or transmitted wave, while maintaining the power efficiency above 90%. For given far-field patterns or 3D objects to reconstruct, we can generate the near-field phase distribution through an iterative process. The aperiodic HCG phase plates we design for holograms are pixelated, and the local geometric parameters for each pixel to achieve desired phase alternation are extracted from our periodic HCG designs. Our aperiodic HCG holograms are simulated using the 3D finite-difference time-domain method. The simulation results confirm that the desired far-field patterns are successfully produced under illumination at the designed wavelength. The HCG holograms are implemented on the quartz wafers, using amorphous silicon as the high-index material. We propose HCG designs at both visible and infrared wavelengths, and our simulation confirms the reconstruction of 3D objects. The high-contrast gratings allow us to realize low-cost, compact, flat, and integrable holograms with sub-micrometer thicknesses.

Statistical controversies in clinical research: requiem for the 3 + 3 design for phase I trials.

PubMed

Paoletti, X; Ezzalfani, M; Le Tourneau, C

2015-09-01

More than 95% of published phase I trials have used the 3 + 3 design to identify the dose to be recommended for phase II trials. However, the statistical community agrees on the limitations of the 3 + 3 design compared with model-based approaches. Moreover, the mechanisms of action of targeted agents strongly challenge the hypothesis that the maximum tolerated dose constitutes the optimal dose, and more outcomes including clinical and biological activity increasingly need to be taken into account to identify the optimal dose. We review key elements from clinical publications and from the statistical literature to show that the 3 + 3 design lacks the necessary flexibility to address the challenges of targeted agents. The design issues raised by expansion cohorts, new definitions of dose-limiting toxicity and trials of combinations are not easily addressed by the 3 + 3 design or its extensions. Alternative statistical proposals have been developed to make a better use of the complex data generated by phase I trials. Their applications require a close collaboration between all actors of early phase clinical trials. © The Author 2015. Published by Oxford University Press on behalf of the European Society for Medical Oncology. All rights reserved. For permissions, please email: journals.permissions@oup.com.

Recognizing Risk-of-Failure in Communication Design Projects

ERIC Educational Resources Information Center

Yee, Joyce; Lievesley, Matthew; Taylor, Louise

2009-01-01

The pace of commercial graphic design practice presents very few opportunities to conduct user research after a project's launch. This makes the design team's ability to anticipate and address risks during the design development phase even more important, recognized in the astute observation from Tim Brown, CEO of leading international design…

Development of the CSI phase-3 evolutionary model testbed

NASA Technical Reports Server (NTRS)

Gronet, M. J.; Davis, D. A.; Tan, M. K.

1994-01-01

This report documents the development effort for the reconfiguration of the Controls-Structures Integration (CSI) Evolutionary Model (CEM) Phase-2 testbed into the CEM Phase-3 configuration. This step responds to the need to develop and test CSI technologies associated with typical planned earth science and remote sensing platforms. The primary objective of the CEM Phase-3 ground testbed is to simulate the overall on-orbit dynamic behavior of the EOS AM-1 spacecraft. Key elements of the objective include approximating the low-frequency appendage dynamic interaction of EOS AM-1, allowing for the changeout of components, and simulating the free-free on-orbit environment using an advanced suspension system. The fundamentals of appendage dynamic interaction are reviewed. A new version of the multiple scaling method is used to design the testbed to have the full-scale geometry and dynamics of the EOS AM-1 spacecraft, but at one-tenth the weight. The testbed design is discussed, along with the testing of the solar array, high gain antenna, and strut components. Analytical performance comparisons show that the CEM Phase-3 testbed simulates the EOS AM-1 spacecraft with good fidelity for the important parameters of interest.

Meteorological Sensor Array (MSA)-Phase I. Volume 3 (Pre-Field Campaign Sensor Calibration)

DTIC Science & Technology

2015-07-01

turbulence impact of the WSMR solar array. 4) Designing , developing, testing , and evaluating integrated Data Acquisition System (DAS) hardware and...ARL-TR-7362 ● JULY 2015 US Army Research Laboratory Meteorological Sensor Array (MSA)–Phase I, Volume 3 (Pre-Field Campaign...NOTICES Disclaimers The findings in this report are not to be construed as an official Department of the Army position unless so designated by

Mountaineer Commercial Scale Carbon Capture and Storage Project Topical Report: Preliminary Public Design Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Guy Cerimele

2011-09-30

This Preliminary Public Design Report consolidates for public use nonproprietary design information on the Mountaineer Commercial Scale Carbon Capture & Storage project. The report is based on the preliminary design information developed during the Phase I - Project Definition Phase, spanning the time period of February 1, 2010 through September 30, 2011. The report includes descriptions and/or discussions for: (1) DOE's Clean Coal Power Initiative, overall project & Phase I objectives, and the historical evolution of DOE and American Electric Power (AEP) sponsored projects leading to the current project; (2) Alstom's Chilled Ammonia Process (CAP) carbon capture retrofit technology andmore » the carbon storage and monitoring system; (3) AEP's retrofit approach in terms of plant operational and integration philosophy; (4) The process island equipment and balance of plant systems for the CAP technology; (5) The carbon storage system, addressing injection wells, monitoring wells, system monitoring and controls logic philosophy; (6) Overall project estimate that includes the overnight cost estimate, cost escalation for future year expenditures, and major project risks that factored into the development of the risk based contingency; and (7) AEP's decision to suspend further work on the project at the end of Phase I, notwithstanding its assessment that the Alstom CAP technology is ready for commercial demonstration at the intended scale.« less

Phosphoric and electric utility fuel cell technology development

NASA Astrophysics Data System (ADS)

Breault, R. D.; Briggs, T. A.; Congdon, J. V.; Demarche, T. E.; Gelting, R. L.; Goller, G. J.; Luoma, W. I.; McCloskey, M. W.; Mientek, A. P.; Obrien, J. J.

1984-01-01

The advancement of electric utility cell stack technology and reduction of cell stack cost was initiated. The cell stack has a nominal 10 ft (2) active area and operates at 120 psia/405(0)F. The program comprises six parallel phases, which culminate in a full height, 10-ft(2) stack verification test: (1) provides the information and services needed to manage the effort, including definition of the prototype commercial power plant; (2) develops the technical base for long term improvements to the cell stack; (3) develops materials and processing techniques for cell stack components incorporating the best available technology; (4) provides the design of hardware and conceptual processing layouts, and updates the power plant definition of Phase 1 to reflect the results of Phases 2 and 3; Phase 5 manufactures the hardware to verify the achievements of Phases 2 and 3, and analyzes the cost of this hardware; and Phase 6 tests the cell stacks assembled from the hardware of Phase 5 to assess the state of development.

Three-Man Solid Electrolyte Carbon Dioxide Electrolysis Breadboard

NASA Technical Reports Server (NTRS)

Isenberg, Arnold O.

1989-01-01

The development of the Three-Man (2.2 lb CO2/man-day) Solid Electrolyte CO2 Electrolysis Breadboard consisted of a Phase 1 and 2 effort. The Phase 1 effort constituted fabrication of three electrolysis cell types and performing parametric testing, off-design testing, and cell life testing. The Phase 2 consisted of the preliminary design, incorporation of palladium (Pd) tubes for hydrogen separation from the electrolyzer cathode feed gases, design support testing, final design, fabrication, and performance testing of the breadboard system. The results of performance tests demonstrated that CO2 electrolysis in an oxygen reclamation system for long duration space-based habitats is feasible. Closure of the oxygen system loop, therefore, can be achieved by CO2 electrolysis. In a two step process the metabolic CO2 and H2O vapor are electrolyzed into O2, H2, and CO. The CO can subsequently be disproportionated into carbon and CO2 in a carbon deposition reactor and the CO2 in turn be recycled and electrolyzed for total O2 recovery. The development effort demonstrated electrolyzer system can be designed and built to operate safely and reliably and the incorporation of Pd tubes for hydrogen diffusion can be integrated safely with predictable performance.

Supporting Creative Responses in Design Education--The Development and Application of the Graphic Design Composition Method

ERIC Educational Resources Information Center

Lu, Hui-Ping; Chen, Jun-Hong; Lee, Chang-Franw

2016-01-01

Inspiration is the primary element of good design. Designers, however, also risk not being able to find inspiration. Novice designers commonly find themselves to be depressed during the conceptual design phase when they fail to find inspiration and the information to be creative. Accordingly, under the graphic design parameter, we have developed…

Langley's CSI evolutionary model: Phase 2

NASA Technical Reports Server (NTRS)

Horta, Lucas G.; Reaves, Mercedes C.; Elliott, Kenny B.; Belvin, W. Keith; Teter, John E.

1995-01-01

Phase 2 testbed is part of a sequence of laboratory models, developed at NASA Langley Research Center, to enhance our understanding on how to model, control, and design structures for space applications. A key problem with structures that must perform in space is the appearance of unwanted vibrations during operations. Instruments, design independently by different scientists, must share the same vehicle causing them to interact with each other. Once in space, these problems are difficult to correct and therefore, prediction via analysis design, and experiments is very important. Phase 2 laboratory model and its predecessors are designed to fill a gap between theory and practice and to aid in understanding important aspects in modeling, sensor and actuator technology, ground testing techniques, and control design issues. This document provides detailed information on the truss structure and its main components, control computer architecture, and structural models generated along with corresponding experimental results.

Design of an ammonia two-phase Prototype Thermal Bus for Space Station

NASA Technical Reports Server (NTRS)

Brown, Richard F.; Gustafson, Eric; Parish, Richard

1987-01-01

The feasibility of two-phase heat transport systems for use on Space Station was demonstrated by testing the Thermal Bus Technology Demonstrator (TBTD) as part of the Integrated Two-Phase System Test in NASA-JSC's Thermal Test Bed. Under contract to NASA-JSC, Grumman is currently developing the successor to the TBTD, the Prototype Thermal Bus System (TBS). The TBS design, which uses ammonia as the working fluid, is intended to achieve a higher fidelity level than the TBTD by incorporating both improvements based on TBTD testing and realistic design margins, and by addressing Space Station issues such as redundancy and maintenance. The TBS is currently being fabricated, with testing scheduled for late 1987/early 1988. This paper describes the TBS design which features fully redundant plumbing loops, five evaporators designed to represent different heat acquisition interfaces, 14 condensers which mate with either space radiators or facility heat exchangers, and several modular components.

Deciding alternative left turn signal phases using expert systems

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chang, E.C.P.

1988-01-01

The Texas Transportation Institute (TTI) conducted a study to investigate the feasibility of applying artificial intelligence (AI) technology and expert systems (ES) design concepts to a traffic engineering problem. Prototype systems were developed to analyze user input, evaluate various reasoning, and suggest suitable left turn phase treatment. These systems were developed using AI programming tools on IBM PC/XT/AT-compatible microcomputers. Two slightly different systems were designed using AI languages; another was built with a knowledge engineering tool. These systems include the PD PROLOG and TURBO PROLOG AI programs, as well as the INSIGHT Production Rule Language.

Development of Permanent Magnet Synchronous Motor Control System for the Traction Purpose of the Gauge Changing Train

NASA Astrophysics Data System (ADS)

Kondo, Keiichiro; Hata, Hiroshi; Yuki, Kazuaki; Naganuma, Katsunori; Matsuoka, Koichi; Hasebe, Toshio

This paper is aimed at providing the designing method of a permanent magnet synchronous motor (PMSM) control system for the high-speed and the single-phase AC powered Gauge Changing Train (GCT). The state-of-the-art electrical motive unit is equipped with downsized direct drive type PMSMs for the simplified gauge changeable truck. Due to the feeding the AC single phase power, we propose a beat-less control for PMSMs. We verify the development results of designing procedures by the experimental results of operation on a high-speed test line in Colorado, USA.

Railroad classification yard design methodology study : East Deerfield Yard, a case study

DOT National Transportation Integrated Search

1980-02-01

This interim report documents the application of a railroad classification yard design methodology to Boston and Maine's East Deerfield Yard Rehabiliation. This case study effort represents Phase 2 of a larger effort to develop a yard design methodol...

Informing efficient randomised controlled trials: exploration of challenges in developing progression criteria for internal pilot studies

PubMed Central

Williamson, Paula R; Gamble, Carrol; O'Connell Francischetto, Elaine; Metcalfe, Chris; Davidson, Peter; Williams, Hywel; Blazeby, Jane M

2017-01-01

Objectives Designing studies with an internal pilot phase may optimise the use of pilot work to inform more efficient randomised controlled trials (RCTs). Careful selection of preagreed decision or ‘progression’ criteria at the juncture between the internal pilot and main trial phases provides a valuable opportunity to evaluate the likely success of the main trial and optimise its design or, if necessary, to make the decision not to proceed with the main trial. Guidance on the appropriate selection and application of progression criteria is, however, lacking. This paper outlines the key issues to consider in the optimal development and review of operational progression criteria for RCTs with an internal pilot phase. Design A structured literature review and exploration of stakeholders' opinions at a Medical Research Council (MRC) Hubs for Trials Methodology Research workshop. Key stakeholders included triallists, methodologists, statisticians and funders. Results There is considerable variation in the use of progression criteria for RCTs with an internal pilot phase, although 3 common issues predominate: trial recruitment, protocol adherence and outcome data. Detailed and systematic reporting around the decision-making process for stopping, amending or proceeding to a main trial is uncommon, which may hamper understanding in the research community about the appropriate and optimal use of RCTs with an internal pilot phase. 10 top tips for the development, use and reporting of progression criteria for internal pilot studies are presented. Conclusions Systematic and transparent reporting of the design, results and evaluation of internal pilot trials in the literature should be encouraged in order to facilitate understanding in the research community and to inform future trials. PMID:28213598

The development of interactive multimedia based on auditory, intellectually, repetition in repetition algorithm learning to increase learning outcome

NASA Astrophysics Data System (ADS)

Munir; Sutarno, H.; Aisyah, N. S.

2018-05-01

This research aims to find out how the development of interactive multimedia based on auditory, intellectually, and repetition can improve student learning outcomes. This interactive multimedia is developed through 5 stages. Analysis stages include the study of literature, questionnaire, interviews and observations. The design phase is done by the database design, flowchart, storyboards and repetition algorithm material while the development phase is done by the creation of web-based framework. Presentation material is adapted to the model of learning such as auditory, intellectually, repetition. Auditory points are obtained by recording the narrative material that presented by a variety of intellectual points. Multimedia as a product is validated by material and media experts. Implementation phase conducted on grade XI-TKJ2 SMKN 1 Garut. Based on index’s gain, an increasing of student learning outcomes in this study is 0.46 which is fair due to interest of student in using interactive multimedia. While the multimedia assessment earned 84.36% which is categorized as very well.

Lightweight solar array blanket tooling, laser welding and cover process technology

NASA Technical Reports Server (NTRS)

Dillard, P. A.

1983-01-01

A two phase technology investigation was performed to demonstrate effective methods for integrating 50 micrometer thin solar cells into ultralightweight module designs. During the first phase, innovative tooling was developed which allows lightweight blankets to be fabricated in a manufacturing environment with acceptable yields. During the second phase, the tooling was improved and the feasibility of laser processing of lightweight arrays was confirmed. The development of the cell/interconnect registration tool and interconnect bonding by laser welding is described.

Range and trend of expected toxicity level (ETL) in standard A + B designs: a report from the Children's Oncology Group.

PubMed

Chen, Zhengjia; Krailo, Mark D; Sun, Junfeng; Azen, Stanley P

2009-03-01

The traditional algorithm-based 3+3 designs are most widely used for their practical simplicity in phase I clinical trials. At early stage, a common belief was that the expected toxicity level (ETL) at the maximum tolerated dose (MTD) should be 33% [Storer, B. Design and analysis of phase I clinical trials. Biometrics 1989;45;925-937, Gorden, N., Willson, J. Using toxicity grades in the design and analysis of cancer phase I clinical trials. Statistics in Medicine 1992; 11: 2063-2075, Mick, R. Phase I Clinical Trial Design. In Schilsky, R., Milano, G., Ratain, M., eds. Principles of Antineoplastic Drug Development and Pharmacology New York, NY: Marcel Dekker, 1996; 29-36]. Recently, Kang and Ahn [Kang, S., Ahn, C. The expected toxicity rate at the maximum tolerated dose in the standard phase I cancer clinical trial design. Drug Information Journal 2001; 35:1189-1199, Kang, S., Ahn, C. An investigation of the traditional algorithm-based designs for phase I cancer clinical trials. Drug Information Journal 2002; 36:865-873] found that the ETL is between 17% and 21% and He et al [He, W., Liu, J., Binkowitz, B., Quan, H. A model-based approach in the estimation of the maximum tolerated dose in phase I cancer clinical trials. Statistics in Medicine 2006; 25(12):2027-42] further reported that the ETL ranges from 19% to 24%. However they only investigated designs where the number of dose levels was at most 20. It has practical significance in designing and conducting phase I clinical trial to definitely assess the full range and trend of ETL by all possible number of tested dose levels in traditional algorithm-based A+B designs, especially 3+3 designs. In this simulation study, we originally find that the ETL decreases monotonically from about 30% to 0% as the number of dose levels increase from 3 to infinity, which will correct the inaccuracy in the common belief among phase I trial investigators. To help better design and conduct phase I trials, we create a table as a reference for the association between ETL and number of dose levels considered in a design when the exact shape of the dose-toxicity relationship is not well understood. We conclude that the number of specified dose levels is an important factor affecting substantially the ETL at MTD and recommend that fewer than 20 dose levels be designated.

Design and analysis of a low-loss linear analog phase modulator for deep space spacecraft X-band transponder applications

NASA Technical Reports Server (NTRS)

Mysoor, N. R.; Mueller, R. O.

1991-01-01

This article summarizes the design concepts, analyses, and development of an X-band (8145 MHz) transponder low-loss linear phase modulator for deep space spacecraft applications. A single-section breadboard circulator-coupled reflection phase modulator has been analyzed, fabricated, and evaluated. A linear phase deviation of 92 deg with a linearity tolerance of +/- 8 percent was measured for this modulator from 8257 MHz to 8634 MHz over the temperature range -20 to 75 C. The measured insertion loss and the static delay variation with temperature were 2 +/- 0.3 dB and 0.16 psec/ C, respectively. Based on this design, cascaded sections have been modeled, and simulations were performed to provide an X-band deep space transponder (DST) phase modulator with +/- 2.5 radians (+/- 143 deg) of peak phase deviation to accommodate downlink signal modulation with composite telemetry data and ranging, with a deviation linearity tolerance of +/- 8 percent and insertion loss of less than 10 +/- 0.5 dB. A two-section phase modulator using constant gamma hyperabrupt varactors and an efficient modulator driver circuit was breadboarded. The measured results satisfy the DST phase-modulator requirements and show excellent agreement with the predicted results.

Integrated low emissions cleanup system for direct coal-fueled turbines

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lippert, T.E.; Newby, R.A.; Alvin, M.A.

1992-12-31

The Westinghouse Electric Corporation, Science & Technology Center (W-STC) is developing an Integrated Low Emissions Cleanup (ILEC) concept for high-temperature gas cleaning to meet environmental standards, as well as to economical gas turbine life. The ILEC concept simultaneously controls sulfur, particulate, and alkali contaminants in high-pressure fuel gases or combustion gases at temperatures up to 1850{degrees}F for advanced power generation systems (PFBC, APFBC, IGCC, DCF7). The objective of this program is to demonstrate, at a bench scale, the conceptual, technical feasibility of the REC concept. The ELEC development program has a 3 phase structure: Phase 1 - laboratory-scale testing; phasemore » 2 - bench-scale equipment; design and fabrication; and phase 3 - bench-scale testing. Phase 1 laboratory testing has been completed. In Phase 1, entrained sulfur and alkali sorbent kinetics were measured and evaluated, and commercial-scale performance was projected. Related cold flow model testing has shown that gas-particle contacting within the ceramic barrier filter vessel will provide a good reactor environment. The Phase 1 test results and the commercial evaluation conducted in the Phase 1 program support the bench-scale facility testing to be performed in Phase 3. Phase 2 is nearing completion with the design and assembly of a modified, bench-scale test facility to demonstrate the technical feasibility of the ILEC features. This feasibility testing will be conducted in Phase 3.« less

Design of analytical systems based on functionality of doped ice.

PubMed

Okada, Tetsuo

2014-01-01

Ice plays an important role for the circulations of some compounds in the global environment. Both the ice surface and the liquid phase developed in a frozen solution are involved in such reactions of the molecules of environmental importance. This leads to the idea that ice can be used to design novel analytical reaction systems. We devised ice chromatography, in which ice particles are used as the liquid chromatographic stationary phase, and have subsequently developed various analytical systems utilizing the functionality of ice. This review focuses our attention on the analytical facets of ice containing impurities such as salts; hereinafter, we call this "doped ice". The design of novel separation systems and use as microreactors with doped ice are mainly discussed.

Lafayette Parish Cooperative Jail Project--LPCJP. Phase III Final Report.

ERIC Educational Resources Information Center

Lafayette Parish School Board, LA.

A three-phase project was conducted to further the education of inmates in the Lafayette (Louisiana) Parish Correctional Center. Phase I of the project was designed to prepare inmates to be eligible to take the General Educational Development (GED) test, and/or to teach life-coping skills so that they would better function in society upon their…

Integrated Computational Materials Engineering Development of Alternative Cu-Be Alloys

DTIC Science & Technology

2012-08-01

Be alloy replacement in highly loaded wear applications . ● Development bushing designs for the enhancement of dynamic wear performance...Material Properties and Tribological Characterization Cu-Based and Co- Based Alloy Concept Selection Requirements Definition Bushing Design and...properties and cost for highly loaded bushing applications ● QuesTek’s NAVAIR-funded SBIR Phase II program demonstrated the feasibility of designing Be-free

The Impact of Early Design Phase Risk Identification Biases on Space System Project Performance

NASA Technical Reports Server (NTRS)

Reeves, John D., Jr.; Eveleigh, Tim; Holzer, Thomas; Sarkani, Shahryar

2012-01-01

Risk identification during the early design phases of complex systems is commonly implemented but often fails to result in the identification of events and circumstances that truly challenge project performance. Inefficiencies in cost and schedule estimation are usually held accountable for cost and schedule overruns, but the true root cause is often the realization of programmatic risks. A deeper understanding of frequent risk identification trends and biases pervasive during space system design and development is needed, for it would lead to improved execution of existing identification processes and methods.

Methods to Develop the Eye-tem Bank to Measure Ophthalmic Quality of Life.

PubMed

Khadka, Jyoti; Fenwick, Eva; Lamoureux, Ecosse; Pesudovs, Konrad

2016-12-01

There is an increasing demand for high-standard, comprehensive, and reliable patient-reported outcome (PRO) instruments in all the disciplines of health care including in ophthalmology and optometry. Over the past two decades, a plethora of PRO instruments have been developed to assess the impact of eye diseases and their treatments. Despite this large number of instruments, significant shortcomings exist for the measurement of ophthalmic quality of life (QoL). Most PRO instruments are short-form instruments designed for clinical use, but this limits their content coverage often poorly targeting any study population other than that which they were developed for. Also, existing instruments are static paper and pencil based and unable to be updated easily leading to outdated and irrelevant item content. Scores obtained from different PRO instruments may not be directly comparable. These shortcomings can be addressed using item banking implemented with computer-adaptive testing (CAT). Therefore, we designed a multicenter project (The Eye-tem Bank project) to develop and validate such PROs to enable comprehensive measurement of ophthalmic QoL in eye diseases. Development of the Eye-tem Bank follows four phases: Phase I, Content Development; Phase II, Pilot Testing and Item Calibration; Phase III, Validation; and Phase IV, Evaluation. This project will deliver technologically advanced comprehensive QoL PROs in the form of item banking implemented via a CAT system in eye diseases. Here, we present a detailed methodological framework of this project.

Technology Plan for the Terrestrial Planet Finder Interferometer

NASA Technical Reports Server (NTRS)

Lawson, Peter R. (Editor); Dooley, Jennifer A. (Editor)

2005-01-01

The technology plan for the Terrestrial Planet Finder Interferometer (TPF-I) describes the breadth of technology development currently envisaged to enable TPF-I to search for habitable worlds around nearby stars. TPF-I is currently in Pre-Phase A (the Advanced Study Phase) of its development. For planning purposes, it is expected to enter into Phase A in 2010 and be launched sometime before 2020. TPF-I is being developed concurrently with the Terrestrial Planet Finder Coronagraph (TPF-C), whose launch is anticipated in 201 6. The missions are being designed with the capability to detect Earth-like planets should they exist in the habitable zones of Sun-like (F,G, and K) stars out to a distance of about 60 light-years. Each mission will have the starlight-suppression and spectroscopic capability to enable the characterization of extrasolar planetary atmospheres, identifying biomarkers and signs of life. TPF-C is designed as a visible-light coronagraph; TPF-I is designed as a mid-infrared formation-flying interferometer. The two missions, working together, promise to yield unambiguous detections and characterizations of Earth-like planets. The challenges of planet detections with mid-infrared formation-flying interferometry are described within this technology plan. The approach to developing the technology is described through roadmaps that lead from our current state of the art through the different phases of mission development to launch. Technology metrics and milestones are given to measure progress. The emphasis of the plan is development and acquisition of technology during pre-Phase A to establish feasibility of the mission to enter Phase A sometime around 2010. Plans beyond 2010 are outlined. The plan contains descriptions of the development of new component technology as well as testbeds that demonstrate the viability of new techniques and technology required for the mission. Starlight-suppression (nulling) and formation-flying technology are highlighted. Although the techniques are described herein, the descriptions are only at a high-level, and tutorial material is not included. The reader is expected to have some familiarity with the principles of long-baseline mid-infrared interferometry. Selected references to existing literature are given where relevant.

The design, development and qualification of a lightweight antenna pointing mechanism

NASA Technical Reports Server (NTRS)

Shmulevitz, M.; Halsband, A.

1996-01-01

This paper describes the design, development, and qualification of a new lightweight and compact Antenna Pointing Mechanism (APM). The APM was specially designed to meet the stringent mass, envelope, and environmental requirements of OFFEQ experimental satellite. During the development phase, some problems were encountered with the brushless DC motors, slip ring contact resistance, and bearing drag torque. All of these problems were resolved, and two APM units have been operating successfully in orbit since April, 1995.

Job Aids: Descriptive Authoring Flowcharts for Phase II--DESIGN of the Instructional Systems Development Model.

ERIC Educational Resources Information Center

Schulz, Russel E.; Farrell, Jean R.

This resource guide for the use of job aids ("how-to-do-it" guidance) for activities identified in the second phase of the Instructional Systems Development Model (ISD) contains an introduction to the use of job aids, as well as descriptive authoring flowcharts for Blocks II.1 through II.4. The introduction includes definitions;…

Development and Validation of HPLC-DAD and UHPLC-DAD Methods for the Simultaneous Determination of Guanylhydrazone Derivatives Employing a Factorial Design.

PubMed

Azevedo de Brito, Wanessa; Gomes Dantas, Monique; Andrade Nogueira, Fernando Henrique; Ferreira da Silva-Júnior, Edeildo; Xavier de Araújo-Júnior, João; Aquino, Thiago Mendonça de; Adélia Nogueira Ribeiro, Êurica; da Silva Solon, Lilian Grace; Soares Aragão, Cícero Flávio; Barreto Gomes, Ana Paula

2017-08-30

Guanylhydrazones are molecules with great pharmacological potential in various therapeutic areas, including antitumoral activity. Factorial design is an excellent tool in the optimization of a chromatographic method, because it is possible quickly change factors such as temperature, mobile phase composition, mobile phase pH, column length, among others to establish the optimal conditions of analysis. The aim of the present work was to develop and validate a HPLC and UHPLC methods for the simultaneous determination of guanylhydrazones with anticancer activity employing experimental design. Precise, exact, linear and robust HPLC and UHPLC methods were developed and validated for the simultaneous quantification of the guanylhydrazones LQM10, LQM14, and LQM17. The UHPLC method was more economic, with a four times less solvent consumption, and 20 times less injection volume, what allowed better column performance. Comparing the empirical approach employed in the HPLC method development to the DoE approach employed in the UHPLC method development, we can conclude that the factorial design made the method development faster, more practical and rational. This resulted in methods that can be employed in the analysis, evaluation and quality control of these new synthetic guanylhydrazones.

Quality by design: a systematic and rapid liquid chromatography and mass spectrometry method for eprosartan mesylate and its related impurities using a superficially porous particle column.

PubMed

Kalariya, Pradipbhai D; Kumar Talluri, Murali V N; Gaitonde, Vinay D; Devrukhakar, Prashant S; Srinivas, Ragampeta

2014-08-01

The present work describes the systematic development of a robust, precise, and rapid reversed-phase liquid chromatography method for the simultaneous determination of eprosartan mesylate and its six impurities using quality-by-design principles. The method was developed in two phases, screening and optimization. During the screening phase, the most suitable stationary phase, organic modifier, and pH were identified. The optimization was performed for secondary influential parameters--column temperature, gradient time, and flow rate using eight experiments--to examine multifactorial effects of parameters on the critical resolution and generated design space representing the robust region. A verification experiment was performed within the working design space and the model was found to be accurate. This study also describes other operating features of the column packed with superficially porous particles that allow very fast separations at pressures available in most liquid chromatography instruments. Successful chromatographic separation was achieved in less than 7 min using a fused-core C18 (100 mm × 2.1 mm, 2.6 μm) column with linear gradient elution of 10 mM ammonium formate (pH 3.0) and acetonitrile as the mobile phase. The method was validated for specificity, linearity, accuracy, precision, and robustness in compliance with the International Conference on Harmonization Q2 (R1) guidelines. The impurities were identified by liquid chromatography with mass spectrometry. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Analog Design for Digital Deployment of a Serious Leadership Game

NASA Technical Reports Server (NTRS)

Maxwell, Nicholas; Lang, Tristan; Herman, Jeffrey L.; Phares, Richard

2012-01-01

This paper presents the design, development, and user testing of a leadership development simulation. The authors share lessons learned from using a design process for a board game to allow for quick and inexpensive revision cycles during the development of a serious leadership development game. The goal of this leadership simulation is to accelerate the development of leadership capacity in high-potential mid-level managers (GS-15 level) in a federal government agency. Simulation design included a mixed-method needs analysis, using both quantitative and qualitative approaches to determine organizational leadership needs. Eight design iterations were conducted, including three user testing phases. Three re-design iterations followed initial development, enabling game testing as part of comprehensive instructional events. Subsequent design, development and testing processes targeted digital application to a computer- and tablet-based environment. Recommendations include pros and cons of development and learner testing of an initial analog simulation prior to full digital simulation development.

Application of Mathematical and Three-Dimensional Computer Modeling Tools in the Planning of Processes of Fuel and Energy Complexes

NASA Astrophysics Data System (ADS)

Aksenova, Olesya; Nikolaeva, Evgenia; Cehlár, Michal

2017-11-01

This work aims to investigate the effectiveness of mathematical and three-dimensional computer modeling tools in the planning of processes of fuel and energy complexes at the planning and design phase of a thermal power plant (TPP). A solution for purification of gas emissions at the design development phase of waste treatment systems is proposed employing mathematical and three-dimensional computer modeling - using the E-nets apparatus and the development of a 3D model of the future gas emission purification system. Which allows to visualize the designed result, to select and scientifically prove economically feasible technology, as well as to ensure the high environmental and social effect of the developed waste treatment system. The authors present results of a treatment of planned technological processes and the system for purifying gas emissions in terms of E-nets. using mathematical modeling in the Simulink application. What allowed to create a model of a device from the library of standard blocks and to perform calculations. A three-dimensional model of a system for purifying gas emissions has been constructed. It allows to visualize technological processes and compare them with the theoretical calculations at the design phase of a TPP and. if necessary, make adjustments.

Development of 780MPa grade gal annealed dual phase steel sheets for automobile

NASA Astrophysics Data System (ADS)

Jiang, Yinghua; Xie, Chunqian; Kuang, Shuang

2018-01-01

As the weight reduction of automotive body and crash safety become much more important factors, in an effort to satisfy these requirements, Shougang has developed 780MPa grade galvannealed dual phase steel sheet. Steel chemistry with low C and low Si was designed for good zinc wettability and spot weldability. And some of elements were added to improve the hole expansibility and work hardening capacity of steel as these effectively refine the microstructure and introduce retained austenite. Newly developed 780MPa grade galvannealed dual phase steels have a high yield strength and a good hole expansibility.

Development of Improved Composite Pressure Vessels for Hydrogen Storage

DOE Office of Scientific and Technical Information (OSTI.GOV)

Newhouse, Norman L.

2016-04-29

Hexagon Lincoln started this DOE project as part of the Hydrogen Storage Engineering Center of Excellence (HSECoE) contract on 1 February 2009. The purpose of the HSECoE was the research and development of viable material based hydrogen storage systems for on-board vehicular applications to meet DOE performance and cost targets. A baseline design was established in Phase 1. Studies were then conducted to evaluate potential improvements, such as alternate fiber, resin, and boss materials. The most promising concepts were selected such that potential improvements, compared with the baseline Hexagon Lincoln tank, resulted in a projected weight reduction of 11 percent,more » volume increase of 4 percent, and cost reduction of 10 percent. The baseline design was updated in Phase 2 to reflect design improvements and changes in operating conditions specified by HSECoE Partners. Evaluation of potential improvements continued during Phase 2. Subscale prototype cylinders were designed and fabricated for HSECoE Partners’ use in demonstrating their components and systems. Risk mitigation studies were conducted in Phase 3 that focused on damage tolerance of the composite reinforcement. Updated subscale prototype cylinders were designed and manufactured to better address the HSECoE Partners’ requirements for system demonstration. Subscale Type 1, Type 3, and Type 4 tanks were designed, fabricated and tested. Laboratory tests were conducted to evaluate vacuum insulated systems for cooling the tanks during fill, and maintaining low temperatures during service. Full scale designs were prepared based on results from the studies of this program. The operating conditions that developed during the program addressed adsorbent systems operating at cold temperatures. A Type 4 tank would provide the lowest cost and lightest weight, particularly at higher pressures, as long as issues with liner compatibility and damage tolerance could be resolved. A Type 1 tank might be the choice if the liner and damage tolerance issues were not resolved, particularly if the operating pressure was reduced.« less

Knowledge-based reusable software synthesis system

NASA Technical Reports Server (NTRS)

Donaldson, Cammie

1989-01-01

The Eli system, a knowledge-based reusable software synthesis system, is being developed for NASA Langley under a Phase 2 SBIR contract. Named after Eli Whitney, the inventor of interchangeable parts, Eli assists engineers of large-scale software systems in reusing components while they are composing their software specifications or designs. Eli will identify reuse potential, search for components, select component variants, and synthesize components into the developer's specifications. The Eli project began as a Phase 1 SBIR to define a reusable software synthesis methodology that integrates reusabilityinto the top-down development process and to develop an approach for an expert system to promote and accomplish reuse. The objectives of the Eli Phase 2 work are to integrate advanced technologies to automate the development of reusable components within the context of large system developments, to integrate with user development methodologies without significant changes in method or learning of special languages, and to make reuse the easiest operation to perform. Eli will try to address a number of reuse problems including developing software with reusable components, managing reusable components, identifying reusable components, and transitioning reuse technology. Eli is both a library facility for classifying, storing, and retrieving reusable components and a design environment that emphasizes, encourages, and supports reuse.

Children and young people's preference of thematic design and colour for their hospital environment.

PubMed

Coad, Jane; Coad, Nigel

2008-03-01

In this innovative project, the views of children and young people were explored regarding their preference of thematic design and colour for their hospital environment in a new children's unit. The novelty of the approach was that it was driven by the preferred choices of children and young people through the use of 'child-friendly' interviews and questionnaires. Informing the study was the development of a group of children and young people who underwent research training, and with support, developed all data collection tools and helped to verify data analysis. A two-phased sequential study was undertaken. During phase 1, 40 interviews were performed with children and young people, including 10 with additional learning needs and physical disabilities while 140 questionnaires were analysed for phase 2 of the study. Notable issues emerged about preferred thematic designs of walls, doors and floors, while new findings were revealed regarding colour preferences for wards, entrances and outpatient areas.

Multi-phase CFD modeling of solid sorbent carbon capture system

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ryan, E. M.; DeCroix, D.; Breault, R.

2013-07-01

Computational fluid dynamics (CFD) simulations are used to investigate a low temperature post-combustion carbon capture reactor. The CFD models are based on a small scale solid sorbent carbon capture reactor design from ADA-ES and Southern Company. The reactor is a fluidized bed design based on a silica-supported amine sorbent. CFD models using both Eulerian–Eulerian and Eulerian–Lagrangian multi-phase modeling methods are developed to investigate the hydrodynamics and adsorption of carbon dioxide in the reactor. Models developed in both FLUENT® and BARRACUDA are presented to explore the strengths and weaknesses of state of the art CFD codes for modeling multi-phase carbon capturemore » reactors. The results of the simulations show that the FLUENT® Eulerian–Lagrangian simulations (DDPM) are unstable for the given reactor design; while the BARRACUDA Eulerian–Lagrangian model is able to simulate the system given appropriate simplifying assumptions. FLUENT® Eulerian–Eulerian simulations also provide a stable solution for the carbon capture reactor given the appropriate simplifying assumptions.« less

Multi-Phase CFD Modeling of Solid Sorbent Carbon Capture System

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ryan, Emily M.; DeCroix, David; Breault, Ronald W.

2013-07-30

Computational fluid dynamics (CFD) simulations are used to investigate a low temperature post-combustion carbon capture reactor. The CFD models are based on a small scale solid sorbent carbon capture reactor design from ADA-ES and Southern Company. The reactor is a fluidized bed design based on a silica-supported amine sorbent. CFD models using both Eulerian-Eulerian and Eulerian-Lagrangian multi-phase modeling methods are developed to investigate the hydrodynamics and adsorption of carbon dioxide in the reactor. Models developed in both FLUENT® and BARRACUDA are presented to explore the strengths and weaknesses of state of the art CFD codes for modeling multi-phase carbon capturemore » reactors. The results of the simulations show that the FLUENT® Eulerian-Lagrangian simulations (DDPM) are unstable for the given reactor design; while the BARRACUDA Eulerian-Lagrangian model is able to simulate the system given appropriate simplifying assumptions. FLUENT® Eulerian-Eulerian simulations also provide a stable solution for the carbon capture reactor given the appropriate simplifying assumptions.« less

Low-cost point-focus solar concentrator, phase 1

NASA Technical Reports Server (NTRS)

Nelson, E. V.; Derbidge, T. C.; Erskine, D.; Maraschin, R. A.; Niemeyer, W. A.; Matsushita, M. J.; Overly, P. T.

1979-01-01

The results of the preliminary design study for the low cost point focus solar concentrator (LCPFSC) development program are presented. A summary description of the preliminary design is given. The design philosophy used to achieve a cost effective design for mass production is described. The concentrator meets all design requirements specified and is based on practical design solutions in every possible way.

Launch vehicle design and GNC sizing with ASTOS

NASA Astrophysics Data System (ADS)

Cremaschi, Francesco; Winter, Sebastian; Rossi, Valerio; Wiegand, Andreas

2018-03-01

The European Space Agency (ESA) is currently involved in several activities related to launch vehicle designs (Future Launcher Preparatory Program, Ariane 6, VEGA evolutions, etc.). Within these activities, ESA has identified the importance of developing a simulation infrastructure capable of supporting the multi-disciplinary design and preliminary guidance navigation and control (GNC) design of different launch vehicle configurations. Astos Solutions has developed the multi-disciplinary optimization and launcher GNC simulation and sizing tool (LGSST) under ESA contract. The functionality is integrated in the Analysis, Simulation and Trajectory Optimization Software for space applications (ASTOS) and is intended to be used from the early design phases up to phase B1 activities. ASTOS shall enable the user to perform detailed vehicle design tasks and assessment of GNC systems, covering all aspects of rapid configuration and scenario management, sizing of stages, trajectory-dependent estimation of structural masses, rigid and flexible body dynamics, navigation, guidance and control, worst case analysis, launch safety analysis, performance analysis, and reporting.

Investigation of acoustic emission coupling techniques

NASA Technical Reports Server (NTRS)

Jolly, W. D.

1988-01-01

A three-phase research program was initiated by NASA in 1983 to investigate the use of acoustic monitoring techniques to detect incipient failure in turbopump bearings. Two prototype acoustic coupler probes were designed and evaluated, and four units of the final probe design were fabricated. Success in this program could lead to development of an on-board monitor which could detect bearing damage in flight and reduce or eliminate the need for disassembly after each flight. This final report reviews the accomplishments of the first two phases and presents the results of fabrication and testing completed in the final phase of the research program.

Design and application of gas-gap heat switches

NASA Technical Reports Server (NTRS)

Chan, C. K.; Ross, R. G., Jr.

1990-01-01

Gas-gap heat switches can serve as an effective means of thermally disconnecting a standby cryocooler when the primary (operating) cooler is connected and vice versa. The final phase of the development and test of a cryogenic heat switch designed for loads ranging from 2 watts at 8 K, to 100 watts at 80 K are described. Achieved heat-switch on/off conductance ratio ranged from 11,000 at 8 K to 2200 at 80 K. A particularly challenging element of heat-switch design is achieving satisfactory operation when large temperatures differentials exist across the switch. A special series of tests and analyses was conducted and used in this Phase-2 activity to evaluate the developed switches for temperature differentials ranging up to 200 K. Problems encountered at the maximum levels are described and analyzed, and means of avoiding the problems in the future are presented. A comprehensive summary of the overall heat-switch design methodology is also presented with special emphasis on lessons learned over the course of the 4-year development effort.

Experiences with an adaptive design for a dose-finding study in patients with osteoarthritis.

PubMed

Miller, Frank; Björnsson, Marcus; Svensson, Ola; Karlsten, Rolf

2014-03-01

Dose-finding studies in non-oncology areas are usually conducted in Phase II of the development process of a new potential medicine and it is key to choose a good design for such a study, as the results will decide if and how to proceed to Phase III. The present article has focus on the design of a dose-finding study for pain in osteoarthritis patients treated with the TRPV1 antagonist AZD1386. We describe different design alternatives in the planning of this study, the reasoning for choosing the adaptive design and experiences with conduct and interim analysis. Three alternatives were proposed: one single dose-finding study with parallel design, a programme with a smaller Phase IIa study followed by a Phase IIb dose-finding study, and an adaptive dose-finding study. We describe these alternatives in detail and explain why the adaptive design was chosen for the study. We give insights in design aspects of the adaptive study, which need to be pre-planned, like interim decision criteria, statistical analysis method and setup of a Data Monitoring Committee. Based on the interim analysis it was recommended to stop the study for futility since AZD1386 showed no significant pain decrease based on the primary variable. We discuss results and experiences from the conduct of the study with the novel design approach. Huge cost savings have been done compared to if the option with one dose-finding design for Phase II had been chosen. However, we point out several challenges with this approach. Copyright © 2014 Elsevier Inc. All rights reserved.

Maximizing return on socioeconomic investment in phase II proof-of-concept trials.

PubMed

Chen, Cong; Beckman, Robert A

2014-04-01

Phase II proof-of-concept (POC) trials play a key role in oncology drug development, determining which therapeutic hypotheses will undergo definitive phase III testing according to predefined Go-No Go (GNG) criteria. The number of possible POC hypotheses likely far exceeds available public or private resources. We propose a design strategy for maximizing return on socioeconomic investment in phase II trials that obtains the greatest knowledge with the minimum patient exposure. We compare efficiency using the benefit-cost ratio, defined to be the risk-adjusted number of truly active drugs correctly identified for phase III development divided by the risk-adjusted total sample size in phase II and III development, for different POC trial sizes, powering schemes, and associated GNG criteria. It is most cost-effective to conduct small POC trials and set the corresponding GNG bars high, so that more POC trials can be conducted under socioeconomic constraints. If δ is the minimum treatment effect size of clinical interest in phase II, the study design with the highest benefit-cost ratio has approximately 5% type I error rate and approximately 20% type II error rate (80% power) for detecting an effect size of approximately 1.5δ. A Go decision to phase III is made when the observed effect size is close to δ. With the phenomenal expansion of our knowledge in molecular biology leading to an unprecedented number of new oncology drug targets, conducting more small POC trials and setting high GNG bars maximize the return on socioeconomic investment in phase II POC trials. ©2014 AACR.

Development of components for an S-band phased array antenna subsystem

NASA Technical Reports Server (NTRS)

1975-01-01

The system requirements, module test data, and S-band phased array subsystem test data are discussed. Of the two approaches to achieving antenna gain (mechanically steered reflector or electronically steered phased array), the phased array approach offers the greatest simplicity and lowest cost (size, weight, power, and dollars) for this medium gain. A competitive system design is described as well as hardware evaluation which will lead to timely availability of this technology for implementing such a system. The objectives of the study were: to fabricate and test six engineering model transmit/receive microelectronics modules; to design, fabricate, and test one dc and logic multilayer manifold; and to integrate and test an S-band phased array antenna subsystem composed of antenna elements, seven T/R modules, RF manifolds and dc manifold.

Converging Redundant Sensor Network Information for Improved Building Control

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dale Tiller; D. Phil; Gregor Henze

2007-09-30

This project investigated the development and application of sensor networks to enhance building energy management and security. Commercial, industrial and residential buildings often incorporate systems used to determine occupancy, but current sensor technology and control algorithms limit the effectiveness of these systems. For example, most of these systems rely on single monitoring points to detect occupancy, when more than one monitoring point could improve system performance. Phase I of the project focused on instrumentation and data collection. During the initial project phase, a new occupancy detection system was developed, commissioned and installed in a sample of private offices and open-planmore » office workstations. Data acquisition systems were developed and deployed to collect data on space occupancy profiles. Phase II of the project demonstrated that a network of several sensors provides a more accurate measure of occupancy than is possible using systems based on single monitoring points. This phase also established that analysis algorithms could be applied to the sensor network data stream to improve the accuracy of system performance in energy management and security applications. In Phase III of the project, the sensor network from Phase I was complemented by a control strategy developed based on the results from the first two project phases: this controller was implemented in a small sample of work areas, and applied to lighting control. Two additional technologies were developed in the course of completing the project. A prototype web-based display that portrays the current status of each detector in a sensor network monitoring building occupancy was designed and implemented. A new capability that enables occupancy sensors in a sensor network to dynamically set the 'time delay' interval based on ongoing occupant behavior in the space was also designed and implemented.« less

Erosion Control and Environment Restoration Plan Development, Matagorda County, Texas. Phase 2. Preliminary Design

DTIC Science & Technology

2013-08-01

recommended groin system. ......................... 37  Figure 23. H1% and Hs at the groin toe as a function of storm surge...phases of work. Keep in mind, the recommended groin system design will advance the shoreline; however, without dune and vegetation management, it...will not create a wider dry beach. Since the existing beach is presumably in equili- brium, the dune and vegetation will advance with the shoreline

Seamless Phase IIa/IIb and enhanced dose-finding adaptive design.

PubMed

Yuan, Jiacheng; Pang, Herbert; Tong, Tiejun; Xi, Dong; Guo, Wenzhao; Mesenbrink, Peter

2016-01-01

In drug development, when the drug class has a relatively well-defined path to regulatory approval and the enrollment is slow with certain patient populations, one may want to consider combining studies of different phases. This article considers combining a proof of concept (POC) study and a dose-finding (DF) study with a control treatment. Conventional DF study designs sometimes are not efficient, or do not have a high probability to find the optimal dose(s) for Phase III trials. This article seeks more efficient DF strategies that allow the economical testing of more doses. Hypothetical examples are simulated to compare the proposed adaptive design vs. the conventional design based on different models of the overall quantitative representation of efficacy, safety, and tolerability. The results show that the proposed adaptive design tests more active doses with higher power and comparable or smaller sample size in a shorter overall study duration for POC and DF, compared with a conventional design.

Development of biology student worksheets to facilitate science process skills of student

NASA Astrophysics Data System (ADS)

Rahayu, Y. S.; Pratiwi, R.; Indana, S.

2018-01-01

This research aims to describe development of Biology student worksheets to facilitate science process skills of student, at the same time to facilitate thinking skills of students in senior high school are equipped with Assesment Sheets. The worksheets development refers to cycle which includes phase analysis (analysis), planning (planning), design (design), development (development), implementation (implementation), evaluation and revision (evaluation and revision). Phase evaluation and revision is an ongoing activity conducted in each phase of the development cycle. That is, after the evaluation of the results of these activities and make revisions at any phase, then continue to the next phase. Based on the test results for grade X, XI, and XII in St. Agnes Surabaya high school, obtained some important findings. The findings are as follows. (1) Developed biology student worksheets could be used to facilitate thinking ability of students in particular skills integrated process that includes components to formulate the problem, formulate hypotheses, determine the study variables, formulate an operational definition of variables, determine the steps in the research, planning data tables, organizing Data in the form of tables/charts, drawing conclusions, (2) Developed biology student worksheets could also facilitate the development of social interaction of students such as working together, listening/respect the opinions of others, assembling equipment and materials, discuss and share information and facilitate the upgrading of skills hands-on student activity. (3) Developed biology worksheets basically could be implemented with the guidance of the teacher step by step, especially for students who have never used a similar worksheet. Guidance at the beginning of this need, especially for worksheets that require special skills or understanding of specific concepts as a prerequisite, such as using a microscope, determine the heart rate, understand the mechanism of specific indicators.

Investigating the Impacts of Design Heuristics on Idea Initiation and Development

ERIC Educational Resources Information Center

Kramer, Julia; Daly, Shanna R.; Yilmaz, Seda; Seifert, Colleen M.; Gonzalez, Richard

2015-01-01

This paper presents an analysis of engineering students' use of Design Heuristics as part of a team project in an undergraduate engineering design course. Design Heuristics are an empirically derived set of cognitive "rules of thumb" for use in concept generation. We investigated heuristic use in the initial concept generation phase,…

Mars oxygen production system design

NASA Technical Reports Server (NTRS)

Cotton, Charles E.; Pillow, Linda K.; Perkinson, Robert C.; Brownlie, R. P.; Chwalowski, P.; Carmona, M. F.; Coopersmith, J. P.; Goff, J. C.; Harvey, L. L.; Kovacs, L. A.

1989-01-01

The design and construction phase is summarized of the Mars oxygen demonstration project. The basic hardware required to produce oxygen from simulated Mars atmosphere was assembled and tested. Some design problems still remain with the sample collection and storage system. In addition, design and development of computer compatible data acquisition and control instrumentation is ongoing.

Design, Test, Redesign: Simulation in Technology, Engineering, and Design Education Classrooms

ERIC Educational Resources Information Center

Swinson, Ronnie; Clark, Aaron C.; Ernst, Jeremy V.; Sutton, Kevin

2016-01-01

Today's engineers, designers, and technologists are often thrust into the role of problem solver, from the initial design phase of a product or process all the way to final development. Many engineers in manufacturing environments are tasked with solving problems and continuously improving processes to enhance company profitability, efficiency,…

Teacher Action Research: The Impact of Inquiry on Curriculum Improvement and Professional Development.

ERIC Educational Resources Information Center

Berlin, Donna F.

The Berlin-White Action Research Model (BWARM) described here was designed to prepare and support teachers in the development, implementation, and evaluation of innovation within their classroom. The year-long program consists of three interrelated phases over four academic quarters: (1) "Pedagogical Awareness," designed to provide knowledge and…

Using Design-Based Research to Improve the Lesson Study Approach to Professional Development in Camden (London)

ERIC Educational Resources Information Center

Brown, Chris; Taylor, Carol; Ponambalum, Lorna

2016-01-01

The Haverstock Primary to Secondary Transition Project was designed to improve the experience of transition to secondary school for vulnerable pupils in Camden (London). The project used lesson study to help primary and secondary practitioners work collaboratively, to develop effective cross-phase pedagogical approaches to teaching…

Man-machine Integration Design and Analysis System (MIDAS) Task Loading Model (TLM) experimental and software detailed design report

NASA Technical Reports Server (NTRS)

Staveland, Lowell

1994-01-01

This is the experimental and software detailed design report for the prototype task loading model (TLM) developed as part of the man-machine integration design and analysis system (MIDAS), as implemented and tested in phase 6 of the Army-NASA Aircrew/Aircraft Integration (A3I) Program. The A3I program is an exploratory development effort to advance the capabilities and use of computational representations of human performance and behavior in the design, synthesis, and analysis of manned systems. The MIDAS TLM computationally models the demands designs impose on operators to aide engineers in the conceptual design of aircraft crewstations. This report describes TLM and the results of a series of experiments which were run this phase to test its capabilities as a predictive task demand modeling tool. Specifically, it includes discussions of: the inputs and outputs of TLM, the theories underlying it, the results of the test experiments, the use of the TLM as both stand alone tool and part of a complete human operator simulation, and a brief introduction to the TLM software design.

Preliminary design of flight hardware for two-phase fluid research

NASA Technical Reports Server (NTRS)

Hustvedt, D. C.; Oonk, R. L.

1982-01-01

This study defined the preliminary designs of flight software for the Space Shuttle Orbiter for three two-phase fluid research experiments: (1) liquid reorientation - to study the motion of liquid in tanks subjected to small accelerations; (2) pool boiling - to study low-gravity boiling from horizontal cylinders; and (3) flow boiling - to study low-gravity forced flow boiling heat transfer and flow phenomena in a heated horizontal tube. The study consisted of eight major tasks: reassessment of the existing experiment designs, assessment of the Spacelab facility approach, assessment of the individual carry-on approach, selection of the preferred approach, preliminary design of flight hardware, safety analysis, preparation of a development plan, estimates of detailed design, fabrication and ground testing costs. The most cost effective design approach for the experiments is individual carry-ons in the Orbiter middeck. The experiments were designed to fit into one or two middeck lockers. Development schedules for the detailed design, fabrication and ground testing ranged from 15 1/2 to 18 months. Minimum costs (in 1981 dollars) ranged from $463K for the liquid reorientation experiment to $998K for the pool boiling experiment.

Hypersonic research engine project. Phase 2: Aerothermodynamic integration model development, data item no. 55-4-21

NASA Technical Reports Server (NTRS)

Jilly, L. F. (Editor)

1975-01-01

The design and development of the Aerothermodynamic Integration Model (AIM) of the Hypersonic Research Engine (HRE) is described. The feasibility of integrating the various analytical and experimental data available for the design of the hypersonic ramjet engine was verified and the operational characteristic and the overall performance of the selected design was determined. The HRE-AIM was designed for operation at speeds of Mach 3 through Mach 8.

Control system design for the MOD-5A 7.3 mW wind turbine generator

NASA Technical Reports Server (NTRS)

Barton, Robert S.; Hosp, Theodore J.; Schanzenbach, George P.

1995-01-01

This paper provides descriptions of the requirements analysis, hardware development and software development phases of the Control System design for the MOD-5A 7.3 mW Wind Turbine Generator. The system, designed by General Electric Company, Advanced Energy Programs Department, under contract DEN 3-153 with NASA Lewis Research Center and DOE, provides real time regulation of rotor speed by control of both generator torque and rotor torque. A variable speed generator system is used to provide both airgap torque control and reactive power control. The wind rotor is designed with segmented ailerons which are positioned to control blade torque. The central component of the control system, selected early in the design process, is a programmable controller used for sequencing, alarm monitoring, communication, and real time control. Development of requirements for use of aileron controlled blades and a variable speed generator required an analytical simulation that combined drivetrain, tower and blade elastic modes with wind disturbances and control behavior. An orderly two phase plan was used for controller software development. A microcomputer based turbine simulator was used to facilitate hardware and software integration and test.

Biomass power for rural development: Phase 2. Technical progress report, April 1--June 30, 1998

DOE Office of Scientific and Technical Information (OSTI.GOV)

Neuhauser, E.

1998-11-01

The project undertaken by the Salix Consortium is a multi-phased, multi-partner endeavor. Phase-1 focused on initial development and testing of the technology and agreements necessary to demonstrate commercial willow production in Phase-2. The Phase-1 objectives have been successfully completed: preparing final design plans for two utility pulverized coal boilers, developing fuel supply plans for the project, obtaining power production commitments from the power companies for Phase-2, obtaining construction and environmental permits, and developing an experimental strategy for crop production and power generation improvements needed to assure commercial success. The R and D effort also addresses environmental issues pertaining to introductionmore » of the willow energy system. Beyond those Phase-1 requirements the Consortium has already successfully demonstrated cofiring at Greenidge Station and developed the required nursery capacity for acreage scale-up. This past summer 105 acres were prepared in advance for the spring planting in 1998. Having completed the above tasks, the Consortium is well positioned to begin Phase-2. In phase-2 every aspect of willow production and power generation from willow will be demonstrated. The ultimate objective of Phase-2 is to transition the work performed under the Rural Energy for the Future project into a thriving, self-supported energy crop enterprise.« less

Space Mission Concept Development Using Concept Maturity Levels

NASA Technical Reports Server (NTRS)

Wessen, Randii R.; Borden, Chester; Ziemer, John; Kwok, Johnny

2013-01-01

Over the past five years, pre-project formulation experts at the Jet Propulsion Laboratory (JPL) has developed and implemented a method for measuring and communicating the maturity of space mission concepts. Mission concept development teams use this method, and associated tools, prior to concepts entering their Formulation Phases (Phase A/B). The organizing structure is Concept Maturity Level (CML), which is a classification system for characterizing the various levels of a concept's maturity. The key strength of CMLs is the ability to evolve mission concepts guided by an incremental set of assessment needs. The CML definitions have been expanded into a matrix form to identify the breadth and depth of analysis needed for a concept to reach a specific level of maturity. This matrix enables improved assessment and communication by addressing the fundamental dimensions (e.g., science objectives, mission design, technical risk, project organization, cost, export compliance, etc.) associated with mission concept evolution. JPL's collaborative engineering, dedicated concept development, and proposal teams all use these and other CML-appropriate design tools to advance their mission concept designs. This paper focuses on mission concept's early Pre-Phase A represented by CMLs 1- 4. The scope was limited due to the fact that CMLs 5 and 6 are already well defined based on the requirements documented in specific Announcement of Opportunities (AO) and Concept Study Report (CSR) guidelines, respectively, for competitive missions; and by NASA's Procedural Requirements NPR 7120.5E document for Projects in their Formulation Phase.

NCI–RTOG Translational Program Strategic Guidelines for the Early-Stage Development of Radiosensitizers

PubMed Central

2013-01-01

The addition of chemotherapeutic agents to ionizing radiation has improved survival in many malignancies. Cure rates may be further improved by adding novel targeted agents to current radiotherapy or radiochemotherapy regimens. Despite promising laboratory data, progress in the clinical development of new drugs with radiation has been limited. To define and address the problems involved, a collaborative effort between individuals within the translational research program of the Radiation Oncology Therapy Group and the National Cancer Institute was established. We discerned challenges to drug development with radiation including: 1) the limited relevance of preclinical work, 2) the pharmaceutical industry’s diminished interest, and 3) the important individual skills and institutional commitments required to ensure a successful program. The differences between early-phase trial designs with and without radiation are noted as substantial. The traditional endpoints for early-phase clinical trials—acute toxicity and maximum-tolerated dose—are of limited value when combining targeted agents with radiation. Furthermore, response rate is not a useful surrogate marker of activity in radiation combination trials.Consequently, a risk-stratified model for drug-dose escalation with radiation is proposed, based upon the known and estimated adverse effects. The guidelines discuss new clinical trial designs, such as the time-to-event continual reassessment method design for phase I trials, randomized phase II “screening” trials, and the use of surrogate endpoints, such as pathological response. It is hoped that by providing a clear pathway, this article will accelerate the rate of drug development with radiation. PMID:23231975

Phase holograms in polymethyl methacrylate

NASA Technical Reports Server (NTRS)

Maker, P. D.; Muller, R. E.

1992-01-01

A procedure is described for the fabrication of complex computer-generated phase holograms in polymethyl methacrylate (PMMA) by means of partial-exposure e-beam lithography and subsequent carefully controlled partial development. Following the development, the pattern appears (rendered in relief) in the PMMA, which then acts as the phase-delay medium. The devices fabricated were designed with 16 equal phase steps per retardation cycle, were up to 3 mm square, and consisted of up to 10 millions of 0.3-2.0-micron square pixels. Data files were up to 60 Mb-long, and the exposure times ranged to several hours. A Fresnel phase lens was fabricated with a diffraction-limited optical performance of 83-percent efficiency.

Application of the generalized reduced gradient method to conceptual aircraft design

NASA Technical Reports Server (NTRS)

Gabriele, G. A.

1984-01-01

The complete aircraft design process can be broken into three phases of increasing depth: conceptual design, preliminary design, and detail design. Conceptual design consists primarily of developing general arrangements and selecting the configuration that optimally satisfies all mission requirements. The result of the conceptual phase is a conceptual baseline configuration that serves as the starting point for the preliminary design phase. The conceptual design of an aircraft involves a complex trade-off of many independent variables that must be investigated before deciding upon the basic configuration. Some of these variables are discrete (number of engines), some represent different configurations (canard vs conventional tail) and some may represent incorporation of new technologies (aluminum vs composite materials). At Lockheed-Georgia, the sizing program is known as GASP (Generalized Aircraft Sizing Program). GASP is a large program containing analysis modules covering the many different disciplines involved fin defining the aricraft, such as aerodynamics, structures, stability and control, mission performance, and cost. These analysis modules provide first-level estimates the aircraft properties that are derived from handbook, experimental, and historical sources.

Design and validation of the eyesafe ladar testbed (ELT) using the LadarSIM system simulator

NASA Astrophysics Data System (ADS)

Neilsen, Kevin D.; Budge, Scott E.; Pack, Robert T.; Fullmer, R. Rees; Cook, T. Dean

2009-05-01

The development of an experimental full-waveform LADAR system has been enhanced with the assistance of the LadarSIM system simulation software. The Eyesafe LADAR Test-bed (ELT) was designed as a raster scanning, single-beam, energy-detection LADAR with the capability of digitizing and recording the return pulse waveform at up to 2 GHz for 3D off-line image formation research in the laboratory. To assist in the design phase, the full-waveform LADAR simulation in LadarSIM was used to simulate the expected return waveforms for various system design parameters, target characteristics, and target ranges. Once the design was finalized and the ELT constructed, the measured specifications of the system and experimental data captured from the operational sensor were used to validate the behavior of the system as predicted during the design phase. This paper presents the methodology used, and lessons learned from this "design, build, validate" process. Simulated results from the design phase are presented, and these are compared to simulated results using measured system parameters and operational sensor data. The advantages of this simulation-based process are also presented.

Application of Analytical Quality by Design concept for bilastine and its degradation impurities determination by hydrophilic interaction liquid chromatographic method.

PubMed

Terzić, Jelena; Popović, Igor; Stajić, Ana; Tumpa, Anja; Jančić-Stojanović, Biljana

2016-06-05

This paper deals with the development of hydrophilic interaction liquid chromatographic (HILIC) method for the analysis of bilastine and its degradation impurities following Analytical Quality by Design approach. It is the first time that the method for bilastine and its impurities is proposed. The main objective was to identify the conditions where an adequate separation in minimal analysis duration could be achieved within a robust region. Critical process parameters which have the most influence on method performance were defined as acetonitrile content in the mobile phase, pH of the aqueous phase and ammonium acetate concentration in the aqueous phase. Box-Behnken design was applied for establishing a relationship between critical process parameters and critical quality attributes. The defined mathematical models and Monte Carlo simulations were used to identify the design space. Fractional factorial design was applied for experimental robustness testing and the method is validated to verify the adequacy of selected optimal conditions: the analytical column Luna(®) HILIC (100mm×4.6mm, 5μm particle size); mobile phase consisted of acetonitrile-aqueous phase (50mM ammonium acetate, pH adjusted to 5.3 with glacial acetic acid) (90.5:9.5, v/v); column temperature 30°C, mobile phase flow rate 1mLmin(-1), wavelength of detection 275nm. Copyright © 2016 Elsevier B.V. All rights reserved.

Plan for the design, development, and implementation, and operation of the National Water Information System

USGS Publications Warehouse

Edwards, M.D.

1987-01-01

The Water Resources Division of the U.S. Geological Survey is developing a National Water Information System (NWIS) that will integrate and replace its existing water data and information systems of the National Water Data Storage and Retrieval System, National Water Data Exchange, National Water-Use Information, and Water Resources Scientific Information Center programs. It will be a distributed data system operated as part of the Division 's Distributed Information System, which is a network of computers linked together through a national telecommunication network known as GEONET. The NWIS is being developed as a series of prototypes that will be integrated as they are completed to allow the development and implementation of the system in a phased manner. It also is being developed in a distributed manner using personnel who work under the coordination of a central NWIS Project Office. Work on the development of the NWIS began in 1983 and it is scheduled for completion in 1990. This document presents an overall plan for the design, development, implementation, and operation of the system. Detailed discussions are presented on each of these phases of the NWIS life cycle. The planning, quality assurance, and configuration management phases of the life cycle also are discussed. The plan is intended to be a working document for use by NWIS management and participants in its design and development and to assist offices of the Division in planning and preparing for installation and operation of the system. (Author 's abstract)

A seamless phase IIB/III adaptive outcome trial: design rationale and implementation challenges.

PubMed

Chen, Y H Joshua; Gesser, Richard; Luxembourg, Alain

2015-02-01

The licensed four-valent prophylactic human papillomavirus vaccine is highly efficacious in preventing cervical, vulvar, vaginal, and anal cancers and related precancers caused by human papillomavirus types 6, 11, 16, and 18. These four types account for approximately 70% of cervical cancers. A nine-valent human papillomavirus vaccine, including the four original types (6, 11, 16, and 18) plus the next five most prevalent types in cervical cancer (31, 33, 45, 52, and 58) could provide approximately 90% overall cervical cancer coverage. To expedite the nine-valent human papillomavirus vaccine clinical development, an adaptive, seamless Phase IIB/III outcome trial with ∼ 15,000 subjects was conducted to facilitate dose formulation selection and provide pivotal evidence of safety and efficacy for regulatory registrations. We discuss the design rationale and implementation challenges of the outcome trial, focusing on the adaptive feature of the seamless Phase IIB/III design. Subjects were enrolled in two parts (Part A and Part B). Approximately 1240 women, 16-26 years of age, were enrolled in Part A for Phase IIB evaluation and equally randomized to one of three dose formulations of the nine-valent human papillomavirus vaccine or the four-valent human papillomavirus vaccine (active control). Based on an interim analysis of immunogenicity and safety, one dose formulation of the nine-valent human papillomavirus vaccine was selected for evaluation in the Phase III part of the study. Subjects enrolled in Part A who received the selected dose formulation of the nine-valent human papillomavirus vaccine or four-valent human papillomavirus vaccine continued to be followed up and contributed to the final efficacy and safety analyses. In addition, ∼ 13,400 women 16-26 years of age were enrolled in Part B, randomized to nine-valent human papillomavirus vaccine at the selected dose formulation or four-valent human papillomavirus vaccine, and followed for immunogenicity, efficacy, and safety. A seamless Phase IIB/III design was justified by the extensive pre-existing knowledge of the licensed four-valent human papillomavirus vaccine and the development objectives for the nine-valent human papillomavirus vaccine. Subjects enrolled in Part A who received either the selected nine-valent human papillomavirus formulation or four-valent human papillomavirus vaccine contributed ∼ 10% of person-years of follow-up due to its earlier start-thereby maximizing the overall efficiency of the trial. Some of the challenges encountered in the implementation of the adaptive design included practical considerations during Phase IIB formulation selection by internal and external committees, End-of-Phase II discussion with health authorities and managing changes in the assay for immunological endpoints. Application of the experience and lesson learned from this seamless adaptive design to other clinical programs may depend on case-by-case consideration. A seamless Phase IIB/III adaptive design was successfully implemented in this large outcome study. The development time of the second-generation nine-valent human papillomavirus vaccine was shortened due to improved statistical efficiency. © The Author(s) 2014.

MINOTAUR (Maryland's innovative orbital technologically advanced University rocket)

NASA Technical Reports Server (NTRS)

Lewis, Mark J.; Akin, Dave; Lind, Charles; Rice, T. (Editor); Vincent, W. (Editor)

1992-01-01

Over the past decade, there has been an increasing interest in designing small commercial launch vehicles. Some of these designs include OSC's Pegasus, and AMROC's Aquila. Even though these vehicles are very different in their overall design characteristics, they all share a common thread of being expensive to design and manufacture. Each of these vehicles has an estimated production and operations cost of over $15000/kg of payload. In response to this high cost factor, the University of Maryland is developing a cost-effective alternative launch vehicle, Maryland's Innovative Orbital Technologically Advanced University Rocket (MINOTAUR). A preliminary cost analysis projects that MINOTAUR will cost under $10000/kg of payload. MINOTAUR will also serve as an enriching project devoted to an entirely student-designed-and-developed launch vehicle. This preliminary design of MINOTAUR was developed entirely by undergraduates in the University of Maryland's Space Vehicle Design class. At the start of the project, certain requirements and priorities were established as a basis from which to begin the design phase: (1) carry a 100 kg payload into a 200 km circular orbit; (2) provide maximum student involvement in the design, manufacturing, and launch phases of the project; and (3) use hybrid propulsion throughout. The following is the list of the project's design priorities (from highest to lowest): (1) safety, (2) cost, (3) minimum development time, (4) maximum use of the off-the-shelf components, (5) performance, and (6) minimum use of pyrotechnics.

A Status Report on the Parachute Development for NASA's Next Manned Spacecraft

NASA Technical Reports Server (NTRS)

Sinclair, Robert

2008-01-01

NASA has determined that the parachute portion of the Landing System for the Crew Exploration Vehicle (CEV) will be Government Furnished Equipment (GFE). The Earth Landing System has been designated CEV Parachute Assembly System (CPAS). Thus a program team was developed consisting of NASA Johnson Space Center (JSC) and Jacobs Engineering through their Engineering and Science Contract Group (ESCG). Following a rigorous competitive phase, Airborne Systems North America was selected to provide the parachute design, testing and manufacturing role to support this team. The development program has begun with some early flight testing of a Generation 1 parachute system. Future testing will continue to refine the design and complete a qualification phase prior to manned flight of the spacecraft. The program team will also support early spacecraft system testing, including a Pad Abort Flight Test in the Fall of 2008

High reliability megawatt transformer/rectifier

NASA Technical Reports Server (NTRS)

Zwass, Samuel; Ashe, Harry; Peters, John W.

1991-01-01

The goal of the two phase program is to develop the technology and design and fabricate ultralightweight high reliability DC to DC converters for space power applications. The converters will operate from a 5000 V dc source and deliver 1 MW of power at 100 kV dc. The power weight density goal is 0.1 kg/kW. The cycle to cycle voltage stability goals was + or - 1 percent RMS. The converter is to operate at an ambient temperature of -40 C with 16 minute power pulses and one hour off time. The uniqueness of the design in Phase 1 resided in the dc switching array which operates the converter at 20 kHz using Hollotron plasma switches along with a specially designed low loss, low leakage inductance and a light weight high voltage transformer. This approach reduced considerably the number of components in the converter thereby increasing the system reliability. To achieve an optimum transformer for this application, the design uses four 25 kV secondary windings to produce the 100 kV dc output, thus reducing the transformer leakage inductance, and the ac voltage stresses. A specially designed insulation system improves the high voltage dielectric withstanding ability and reduces the insulation path thickness thereby reducing the component weight. Tradeoff studies and tests conducted on scaled-down model circuits and using representative coil insulation paths have verified the calculated transformer wave shape parameters and the insulation system safety. In Phase 1 of the program a converter design approach was developed and a preliminary transformer design was completed. A fault control circuit was designed and a thermal profile of the converter was also developed.

Human Modeling Evaluations in Microgravity Workstation and Restraint Development

NASA Technical Reports Server (NTRS)

Whitmore, Mihriban; Chmielewski, Cynthia; Wheaton, Aneice; Hancock, Lorraine; Beierle, Jason; Bond, Robert L. (Technical Monitor)

1999-01-01

The International Space Station (ISS) will provide long-term missions which will enable the astronauts to live and work, as well as, conduct research in a microgravity environment. The dominant factor in space affecting the crew is "weightlessness" which creates a challenge for establishing workstation microgravity design requirements. The crewmembers will work at various workstations such as Human Research Facility (HRF), Microgravity Sciences Glovebox (MSG) and Life Sciences Glovebox (LSG). Since the crew will spend considerable amount of time at these workstations, it is critical that ergonomic design requirements are integral part of design and development effort. In order to achieve this goal, the Space Human Factors Laboratory in the Johnson Space Center Flight Crew Support Division has been tasked to conduct integrated evaluations of workstations and associated crew restraints. Thus, a two-phase approach was used: 1) ground and microgravity evaluations of the physical dimensions and layout of the workstation components, and 2) human modeling analyses of the user interface. Computer-based human modeling evaluations were an important part of the approach throughout the design and development process. Human modeling during the conceptual design phase included crew reach and accessibility of individual equipment, as well as, crew restraint needs. During later design phases, human modeling has been used in conjunction with ground reviews and microgravity evaluations of the mock-ups in order to verify the human factors requirements. (Specific examples will be discussed.) This two-phase approach was the most efficient method to determine ergonomic design characteristics for workstations and restraints. The real-time evaluations provided a hands-on implementation in a microgravity environment. On the other hand, only a limited number of participants could be tested. The human modeling evaluations provided a more detailed analysis of the setup. The issues identified during the real-time testing were investigated in the human modeling analyses. In some cases, the opposite was true where preliminary human modeling analyses provided the design engineers with critical issues that needed to be addressed further. This extensive approach provided an effective means to fully address ergonomic design considerations and accurately identify critical issues.

Scaling of Two-Phase Flows to Partial-Earth Gravity

NASA Technical Reports Server (NTRS)

Hurlbert, Kathryn M.; Witte, Larry C.

2003-01-01

A report presents a method of scaling, to partial-Earth gravity, of parameters that describe pressure drops and other characteristics of two-phase (liquid/ vapor) flows. The development of the method was prompted by the need for a means of designing two-phase flow systems to operate on the Moon and on Mars, using fluid-properties and flow data from terrestrial two-phase-flow experiments, thus eliminating the need for partial-gravity testing. The report presents an explicit procedure for designing an Earth-based test bed that can provide hydrodynamic similarity with two-phase fluids flowing in partial-gravity systems. The procedure does not require prior knowledge of the flow regime (i.e., the spatial orientation of the phases). The method also provides for determination of pressure drops in two-phase partial-gravity flows by use of a generalization of the classical Moody chart (previously applicable to single-phase flow only). The report presents experimental data from Mars- and Moon-activity experiments that appear to demonstrate the validity of this method.

Using Android-Based Educational Game for Learning Colloid Material

NASA Astrophysics Data System (ADS)

Sari, S.; Anjani, R.; Farida, I.; Ramdhani, M. A.

2017-09-01

This research is based on the importance of the development of student’s chemical literacy on Colloid material using Android-based educational game media. Educational game products are developed through research and development design. In the analysis phase, material analysis is performed to generate concept maps, determine chemical literacy indicators, game strategies and set game paths. In the design phase, product packaging is carried out, then validation and feasibility test are performed. Research produces educational game based on Android that has the characteristics that is: Colloid material presented in 12 levels of game in the form of questions and challenges, presents visualization of discourse, images and animation contextually to develop the process of thinking and attitude. Based on the analysis of validation and trial results, the product is considered feasible to use.

Lessons learned in the transition to ADA from FORTRAN at NASA/Goddard. M.S. Thesis

NASA Technical Reports Server (NTRS)

Brophy, Carolyn Elizabeth

1989-01-01

A case study was done at Goddard Space Flight Center, in which two dynamics satellite simulators are developed from the same requirements, one in Ada and the other in FORTRAN. The purpose of the research was to find out how well the prescriptive Ada development model worked to develop the Ada simulator. The FORTRAN simulator development, as well as past FORTRAN developments, provided a baseline for comparison. Since this was the first simulator developed here, the prescriptive Ada development model had many similarities to the usual FORTRAN development model. However, it was modified to include longer design and shorter testing phases, which is generally expected with Ada development. One surprising result was that the percentage of time the Ada project spent in the various development activities was very similar to the percentage of time spent in these activities when doing a FORTRAN project. Another surprising finding was the difficulty the Ada team had with unit testing as well as with integration. In retrospect it is realized that adding additional steps to the design phase, such as an abstract data type analysis, and certain guidelines to the implementation phase, such as to use primarily library units and nest sparingly, would have made development much easier.

Software development for airborne radar

NASA Astrophysics Data System (ADS)

Sundstrom, Ingvar G.

Some aspects for development of software in a modern multimode airborne nose radar are described. First, an overview of where software is used in the radar units is presented. The development phases-system design, functional design, detailed design, function verification, and system verification-are then used as the starting point for the discussion. Methods, tools, and the most important documents are described. The importance of video flight recording in the early stages and use of a digital signal generators for performance verification is emphasized. Some future trends are discussed.

Automated CPX support system preliminary design phase

NASA Technical Reports Server (NTRS)

Bordeaux, T. A.; Carson, E. T.; Hepburn, C. D.; Shinnick, F. M.

1984-01-01

The development of the Distributed Command and Control System (DCCS) is discussed. The development of an automated C2 system stimulated the development of an automated command post exercise (CPX) support system to provide a more realistic stimulus to DCCS than could be achieved with the existing manual system. An automated CPX system to support corps-level exercise was designed. The effort comprised four tasks: (1) collecting and documenting user requirements; (2) developing a preliminary system design; (3) defining a program plan; and (4) evaluating the suitability of the TRASANA FOURCE computer model.

A process for prototyping onboard payload displays for Space Station Freedom

NASA Technical Reports Server (NTRS)

Moore, Loretta A.

1992-01-01

Significant advances have been made in the area of Human-Computer Interface design. However, there is no well-defined process for going from user interface requirements to user interface design. Developing and designing a clear and consistent user interface for medium to large scale systems is a very challenging and complex task. The task becomes increasingly difficult when there is very little guidance and procedures on how the development process should flow from one stage to the next. Without a specific sequence of development steps each design becomes difficult to repeat, to evaluate, to improve, and to articulate to others. This research contributes a process which identifies the phases of development and products produced as a result of each phase for a rapid prototyping process to be used to develop requirements for the onboard payload displays for Space Station Freedom. The functional components of a dynamic prototyping environment in which this process can be carried out is also discussed. Some of the central questions which are answered here include: How does one go from specifications to an actual prototype? How is a prototype evaluated? How is usability defined and thus measured? How do we use the information from evaluation in redesign of an interface? and Are there techniques which allow for convergence on a design?

A Semi-flexible 64-channel Receive-only Phased Array for Pediatric Body MRI at 3T

PubMed Central

Zhang, Tao; Grafendorfer, Thomas; Cheng, Joseph Y.; Ning, Peigang; Rainey, Bob; Giancola, Mark; Ortman, Sarah; Robb, Fraser J.; Calderon, Paul D.; Hargreaves, Brian A.; Lustig, Michael; Scott, Greig C.; Pauly, John M.; Vasanawala, Shreyas S.

2015-01-01

Purpose To design, construct, and validate a semi-flexible 64-channel receive-only phased array for pediatric body MRI at 3T. Methods A 64-channel receive-only phased array was developed and constructed. The designed flexible coil can easily conform to different patient sizes with non-overlapping coil elements in the transverse plane. It can cover a field of view of up to 44 × 28 cm2 and removes the need for coil repositioning for body MRI patients with multiple clinical concerns. The 64-channel coil was compared with a 32-channel standard coil for signal-to-noise ratio (SNR) and parallel imaging performances on different phantoms. With IRB approval and informed consent/assent, the designed coil was validated on 21 consecutive pediatric patients. Results The pediatric coil provided higher SNR than the standard coil on different phantoms, with the averaged SNR gain at least 23% over a depth of 7 cm along the cross-section of phantoms. It also achieved better parallel imaging performance under moderate acceleration factors. Good image quality (average score 4.6 out of 5) was achieved using the developed pediatric coil in the clinical studies. Conclusion A 64-channel semi-flexible receive-only phased array has been developed and validated to facilitate high quality pediatric body MRI at 3T. PMID:26418283

Hydrophilic interaction liquid chromatography in analysis of granisetron HCl and its related substances. Retention mechanisms and method development.

PubMed

Maksić, Jelena; Tumpa, Anja; Stajić, Ana; Jovanović, Marko; Rakić, Tijana; Jančić-Stojanović, Biljana

2016-05-10

In this paper separation of granisetron and its two related substances in HILIC mode is presented. Separation was done on silica column derivatized with sulfoalkylbetaine groups (ZIC-HILIC). Firstly, retention mechanisms were assessed whereby retention factors of substances were followed in wide range of acetonitrile content (80-97%), at constant concentration of aqueous buffer (10mM) as well as at constant pH value of 3.0. Further, in order to developed optimal HILIC method, Design of Experiments (DoE) methodology was applied. For optimization full factorial design 3(2) was employed. Influence of acetonitrile content and ammonium acetate concentration were investigated while pH of the water phase was kept at 3.3. Adequacy of obtained mathematical models was confirmed by ANOVA. Optimization goals (α>1.15 and minimal run time) were accomplished with 94.7% of acetonitrile in mobile phase and 70 mM of ammonium acetate in water phase. Optimal point was in the middle of defined Design Space. In the next phase, robustness was experimetally tested by Rechtschaffen design. The investigated factors and their levels were: acetonitrile content (±1%), ammonium acetate molarity in water phase (±2 mM), pH value of water phase (±0.2) and column temperature (±4 °C). The validation scope included selectivity, linearity, accuracy and precision as well as determination of limit of detection (LOD) and limit of quantification (LOQ) for the related substances. Additionally, the validation acceptance criteria were met in all cases. Finally, the proposed method could be successfully utilized for estimation of granisetron HCl and its related substances in tablets and parenteral dosage forms, as well as for monitoring degradation under various stress conditions. Copyright © 2016 Elsevier B.V. All rights reserved.

A Project to Design, Develop, Implement, Test, Evaluate and Disseminate an Associate Degree Curriculum to Train Solar Engineering Technicians.

ERIC Educational Resources Information Center

Lowenstein, Michael Z.; Orsak, Charles

Phase 1 of a project in curriculum design and course development identified and is now developing a two-year solar engineering curriculum in response to the immediate need for trained solar manpower as indicated by research. The student-centered curriculum involves courses flowing from device to theory, intermixing of support and technical courses…

Cost estimating methods for advanced space systems

NASA Technical Reports Server (NTRS)

Cyr, Kelley

1994-01-01

NASA is responsible for developing much of the nation's future space technology. Cost estimates for new programs are required early in the planning process so that decisions can be made accurately. Because of the long lead times required to develop space hardware, the cost estimates are frequently required 10 to 15 years before the program delivers hardware. The system design in conceptual phases of a program is usually only vaguely defined and the technology used is so often state-of-the-art or beyond. These factors combine to make cost estimating for conceptual programs very challenging. This paper describes an effort to develop parametric cost estimating methods for space systems in the conceptual design phase. The approach is to identify variables that drive cost such as weight, quantity, development culture, design inheritance and time. The nature of the relationships between the driver variables and cost will be discussed. In particular, the relationship between weight and cost will be examined in detail. A theoretical model of cost will be developed and tested statistically against a historical database of major research and development projects.

LSST (Hoop/Column) Maypole Antenna Development Program, phase 1, part 1

NASA Technical Reports Server (NTRS)

Sullivan, M. R.

1982-01-01

The first of a two-phase program was performed to develop the technology necessary to evaluate, design, manufacture, package, transport and deploy the hoop/column deployable antenna reflector by means of a ground based program. The hoop/column concept consists of a cable stiffened large diameter hoop and central column structure that supports and contours a radio frequency reflective mesh surface. Mission scenarios for communications, radiometer and radio astronomy, were studied. The data to establish technology drivers that resulted in a specification of a point design was provided. The point design is a multiple beam quadaperture offset antenna system wich provides four separate offset areas of illumination on a 100 meter diameter symmetrical parent reflector. The periphery of the reflector is a hoop having 48 segments that articulate into a small stowed volume around a center extendable column. The hoop and column are structurally connected by graphite and quartz cables. The prominence of cables in the design resulted in the development of advanced cable technology. Design verification models were built of the hoop, column, and surface stowage subassemblies. Model designs were generated for a half scale sector of the surface and a 1/6 scale of the complete deployable reflector.

Congestion management system/IVHS program study Birmingham, Alabama : phase 1, report

DOT National Transportation Integrated Search

1995-04-01

The Inter-modal Surface Transportation Efficiency Act of 1991 (ISTEA) required states and : metropolitan areas designated as transportation management areas develop congestion : management systems. The Birmingham Planning Area is designated as a non-...

Congestion Management System/IVHS Program Study for Birmingham, Alabama. Phase 1 Report

DOT National Transportation Integrated Search

1995-04-01

The Inter-modal Surface Transportation Efficiency Act of 1991 (ISTEA) required states and : metropolitan areas designated as transportation management areas develop congestion : management systems. The Birmingham Planning Area is designated as a non-...

Preliminary design of nine high speed civil transports

NASA Technical Reports Server (NTRS)

Sandlin, Doral; Vantriet, Robert; Soban, Dani; Hoang, TY

1992-01-01

Sixty senior design students at Cal Poly, SLO have completed a year-long project to design the next generation of High Speed Civil Transports (HSCT). The design process was divided up into three distinct phases. The first third of the project was devoted entirely to research into the special problems associated with an HSCT. These included economic viability, airport compatibility, high speed aerodynamics, sonic boom minimization, environmental impact, and structures and materials. The result of this research was the development of nine separate Requests for Proposal (RFP) that outlined reasonable yet challenging design criteria for the aircraft. All were designed to be technically feasible in the year 2015. The next phase of the project divided the sixty students into nine design groups. Each group, with its own RFP, completed a Class 1 preliminary design of an HSCT. The nine configurations varied from conventional double deltas to variable geometry wings to a pivoting oblique wing design. The final phase of the project included a more detailed Class 2 sizing as well as performance and stability and control analysis. Cal Poly, San Luis Obispo presents nine unique solutions to the same problem: that of designing an economically viable, environmentally acceptable, safe and comfortable supersonic transport.

IDEAS (Integrate, Design, Assess, and Share): A Framework and Toolkit of Strategies for the Development of More Effective Digital Interventions to Change Health Behavior.

PubMed

Mummah, Sarah Ann; Robinson, Thomas N; King, Abby C; Gardner, Christopher D; Sutton, Stephen

2016-12-16

Developing effective digital interventions to change health behavior has been a challenging goal for academics and industry players alike. Guiding intervention design using the best combination of approaches available is necessary if effective technologies are to be developed. Behavioral theory, design thinking, user-centered design, rigorous evaluation, and dissemination each have widely acknowledged merits in their application to digital health interventions. This paper introduces IDEAS, a step-by-step process for integrating these approaches to guide the development and evaluation of more effective digital interventions. IDEAS is comprised of 10 phases (empathize, specify, ground, ideate, prototype, gather, build, pilot, evaluate, and share), grouped into 4 overarching stages: Integrate, Design, Assess, and Share (IDEAS). Each of these phases is described and a summary of theory-based behavioral strategies that may inform intervention design is provided. The IDEAS framework strives to provide sufficient detail without being overly prescriptive so that it may be useful and readily applied by both investigators and industry partners in the development of their own mHealth, eHealth, and other digital health behavior change interventions. ©Sarah Ann Mummah, Thomas N Robinson, Abby C King, Christopher D Gardner, Stephen Sutton. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 16.12.2016.

Thermophotovoltaic space power system, phase 3

NASA Technical Reports Server (NTRS)

Horne, W. E.; Lancaster, C.

1987-01-01

Work performed on a research and development program to establish the feasibility of a solar thermophotovoltaic space power generation concept was summarized. The program was multiphased. The earlier work is summarized and the work on the current phase is detailed as it pertains to and extends the earlier work. Much of the experimental hardware and materials development was performed on the internal program. Experimental measurements and data evaluation were performed on the contracted effort. The objectives of the most recent phase were: to examine the thermal control design in order to optimize it for lightweight and low cost; to examine the concentrator optics in an attempt to relieve pointing accuracy requirements to + or - 2 degrees about the optical axis; and to use the results of the thermal and optical studies to synthesize a solar thermophotovoltaic (STPV) module design that is optimized for space application.

Design of a simulation environment for laboratory management by robot organizations

NASA Technical Reports Server (NTRS)

Zeigler, Bernard P.; Cellier, Francois E.; Rozenblit, Jerzy W.

1988-01-01

This paper describes the basic concepts needed for a simulation environment capable of supporting the design of robot organizations for managing chemical, or similar, laboratories on the planned U.S. Space Station. The environment should facilitate a thorough study of the problems to be encountered in assigning the responsibility of managing a non-life-critical, but mission valuable, process to an organized group of robots. In the first phase of the work, we seek to employ the simulation environment to develop robot cognitive systems and strategies for effective multi-robot management of chemical experiments. Later phases will explore human-robot interaction and development of robot autonomy.

Space Station Freedom electrical power system hardware commonality with the United States Polar Platform

NASA Technical Reports Server (NTRS)

Rieker, Lorra L.; Haraburda, Francis M.

1989-01-01

Information is presented on how the concept of commonality is being implemented with respect to electric power system hardware for the Space Station Freedom and the U.S. Polar Platform. Included is a historical account of the candidate common items which have the potential to serve the same power system functions on both Freedom and the Polar Platform. The Space Station program and objectives are described, focusing on the test and development responsibilities. The program definition and preliminary design phase and the design and development phase are discussed. The goal of this work is to reduce the program cost.

Solid polymer electrolyte water electrolysis system development. [to generate oxygen for manned space station applications

NASA Technical Reports Server (NTRS)

1975-01-01

Solid polymer electrolyte technology used in a water electrolysis system (WES) to generate oxygen and hydrogen for manned space station applications was investigated. A four-man rated, low pressure breadboard water electrolysis system with the necessary instrumentation and controls was fabricated and tested. A six man rated, high pressure, high temperature, advanced preprototype WES was developed. This configuration included the design and development of an advanced water electrolysis module, capable of operation at 400 psig and 200 F, and a dynamic phase separator/pump in place of a passive phase separator design. Evaluation of this system demonstrated the goal of safe, unattended automated operation at high pressure and high temperature with an accumulated gas generation time of over 1000 hours.

Advanced manufacturing development of a composite empennage component for L-1011 aircraft

NASA Technical Reports Server (NTRS)

Alva, T.; Henkel, J.; Johnson, R.; Carll, B.; Jackson, A.; Mosesian, B.; Brozovic, R.; Obrien, R.; Eudaily, R.

1982-01-01

This is the final report of technical work conducted during the fourth phase of a multiphase program having the objective of the design, development and flight evaluation of an advanced composite empennage component manufactured in a production environment at a cost competitive with those of its metal counterpart, and at a weight savings of at least 20 percent. The empennage component selected for this program is the vertical fin box of the L-1011 aircraft. The box structure extends from the fuselage production joint to the tip rib and includes front and rear spars. During Phase 4 of the program, production quality tooling was designed and manufactured to produce three sets of covers, ribs, spars, miscellaneous parts, and subassemblies to assemble three complete ACVF units. Recurring and nonrecurring cost data were compiled and documented in the updated producibility/design to cost plan. Nondestruct inspections, quality control tests, and quality acceptance tests were performed in accordance with the quality assurance plan and the structural integrity control plan. Records were maintained to provide traceability of material and parts throughout the manufacturing development phase. It was also determined that additional tooling would not be required to support the current and projected L-1011 production rate.

Synthesis and evaluation of phase detectors for active bit synchronizers

NASA Technical Reports Server (NTRS)

Mcbride, A. L.

1974-01-01

Self-synchronizing digital data communication systems usually use active or phase-locked loop (PLL) bit synchronizers. The three main elements of PLL synchronizers are the phase detector, loop filter, and the voltage controlled oscillator. Of these three elements, phase detector synthesis is the main source of difficulty, particularly when the received signals are demodulated square-wave signals. A phase detector synthesis technique is reviewed that provides a physically realizable design for bit synchronizer phase detectors. The development is based upon nonlinear recursive estimation methods. The phase detector portion of the algorithm is isolated and analyzed.

Benchmarking Evaluation Results for Prototype Extravehicular Activity Gloves

NASA Technical Reports Server (NTRS)

Aitchison, Lindsay; McFarland, Shane

2012-01-01

The Space Suit Assembly (SSA) Development Team at NASA Johnson Space Center has invested heavily in the advancement of rear-entry planetary exploration suit design but largely deferred development of extravehicular activity (EVA) glove designs, and accepted the risk of using the current flight gloves, Phase VI, for unique mission scenarios outside the Space Shuttle and International Space Station (ISS) Program realm of experience. However, as design reference missions mature, the risks of using heritage hardware have highlighted the need for developing robust new glove technologies. To address the technology gap, the NASA Game-Changing Technology group provided start-up funding for the High Performance EVA Glove (HPEG) Project in the spring of 2012. The overarching goal of the HPEG Project is to develop a robust glove design that increases human performance during EVA and creates pathway for future implementation of emergent technologies, with specific aims of increasing pressurized mobility to 60% of barehanded capability, increasing the durability by 100%, and decreasing the potential of gloves to cause injury during use. The HPEG Project focused initial efforts on identifying potential new technologies and benchmarking the performance of current state of the art gloves to identify trends in design and fit leading to establish standards and metrics against which emerging technologies can be assessed at both the component and assembly levels. The first of the benchmarking tests evaluated the quantitative mobility performance and subjective fit of four prototype gloves developed by Flagsuit LLC, Final Frontier Designs, LLC Dover, and David Clark Company as compared to the Phase VI. All of the companies were asked to design and fabricate gloves to the same set of NASA provided hand measurements (which corresponded to a single size of Phase Vi glove) and focus their efforts on improving mobility in the metacarpal phalangeal and carpometacarpal joints. Four test subjects representing the design ]to hand anthropometry completed range of motion, grip/pinch strength, dexterity, and fit evaluations for each glove design in both the unpressurized and pressurized conditions. This paper provides a comparison of the test results along with a detailed description of hardware and test methodologies used.

The Application of Concurrent Engineering Tools and Design Structure Matrix in Designing Tire

NASA Astrophysics Data System (ADS)

Ginting, Rosnani; Fachrozi Fitra Ramadhan, T.

2016-02-01

The development of automobile industry in Indonesia is growing rapidly. This phenomenon causes companies related to the automobile industry such as tire industry must develop products based on customers’ needs and considering the timeliness of delivering the product to the customer. It could be reached by applying strategic planning in developing an integrated concept of product development. This research was held in PT. XYZ that applied the sequential approach in designing and developing products. The need to improve in one stage of product development could occur re-designing that needs longer time in developing a new product. This research is intended to get an integrated product design concept of tire pertaining to the customer's needs using Concurrent Engineering Tools by implementing the two-phased of product development. The implementation of Concurrent Engineering approach results in applying the stage of project planning, conceptual design, and product modules. The product modules consist of four modules that using Product Architecture - Design Structure Matrix to ease the designing process of new product development.

A design procedure for fan inflow control structures

NASA Technical Reports Server (NTRS)

Gedge, M. R.

1980-01-01

Significant differences exist in the noise generated by engine in flight and engines operating on the test stand. It was observed that these differences can be reduced by use of an inflow control structure (ICS) in the static test configuration. The results of the second phase of a three phase program are described and the results of a test program conducted to assess and modify various theoretical models, leading to the development of an ICS design system is summarized.

Aeroservoelastic stabilization technique refinement for hypersonic flight vehicles

NASA Technical Reports Server (NTRS)

Cheng, Peter Y.; Chan, Samuel Y.; Myers, Thomas T.; Klyde, David H.; Mcruer, Duane T.

1992-01-01

Conventional gain-stabilization techniques introduce low frequency effective time delays which can be troublesome from the viewpoint of SSTOV vehicles' flying qualities. These time delays can be alleviated through a blending of gain-stabilization and phase-stabilization techniques; the resulting hybrid phase stabilization (HPS) for the low-frequency structural modes has been noted to have greater residual response than a conventional gain-stabilizer design. HPS design procedures are presently refined, and residual response metrics are developed.

A Summer Enrichment and Reinforcement Program in the School of Veterinary Medicine at Tuskegee Institute, Alabama. A Program Designed to Respond to a Challenge: Increased Minority and Disadvantaged Representation in Veterinary Medicine.

ERIC Educational Resources Information Center

Poole, Georgia C.; Adams, Eugene W.

This report describes a pre-entry summer program at the School of Veterinary Medicine at Tuskegee Institute, Alabama, designed to develop attitudinal readiness and coqnitive abilities of students who face a high risk of attrition because of inadequate learning skills. The program, which runs for eight weeks, consists of three phases: 1) phase one,…

History of San Marco

NASA Technical Reports Server (NTRS)

Caporale, A. J.

1968-01-01

A brief history is reported of the first San Marco project, a joint program of the United States and Italy. The Project was a three phase effort to investigate upper air density and associated ionosphere phenomena. The initial phase included the design and development of the spacecraft, the experiments, the launch complex, and a series of suborbital flights, from Wallops Island. The second phase, consisting of designing, fabricating, and testing a spacecraft for the first orbital mission, culminated in an orbital launch also from Wallops Island. The third phase consisted of further refining the experiments and spacecraft instrumentation and of establishing a full-bore scout complex in Kenya. The launch of San Marco B, in April 1967, from this complex into an equatorial orbit, concluded the initial San Marco effort.

An Integrated Approach to Risk Assessment for Concurrent Design

NASA Technical Reports Server (NTRS)

Meshkat, Leila; Voss, Luke; Feather, Martin; Cornford, Steve

2005-01-01

This paper describes an approach to risk assessment and analysis suited to the early phase, concurrent design of a space mission. The approach integrates an agile, multi-user risk collection tool, a more in-depth risk analysis tool, and repositories of risk information. A JPL developed tool, named RAP, is used for collecting expert opinions about risk from designers involved in the concurrent design of a space mission. Another in-house developed risk assessment tool, named DDP, is used for the analysis.

77 FR 40693 - Bureau of Political-Military Affairs: Directorate of Defense Trade Controls; Notifications to the...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-10

..., including technical data, and defense services for the design, development, manufacture, production... support the design, manufacturing and delivery phases of the SES-8 Commercial Communications Satellite... design, manufacture, test, on-ground launch-site delivery, completion of in-orbit testing and long-term...

Implementing E-Learning Designed Courses in General Education

ERIC Educational Resources Information Center

Nuangchalerm, Prasart; Sakkumduang, Krissada; Uhwha, Suleepornn; Chansirisira, Pacharawit

2014-01-01

The aim of this study is to implement e-learning designed course for general education. The study employed 3 phases for developing e-learning course: contextual study, designing, and implementing. Two courses general education, 217 undergraduate students are participated the study. Research tool consisted of interview about e-learning form and…

49 CFR 236.913 - Filing and approval of PSPs.

Code of Federal Regulations, 2011 CFR

2011-10-01

... architectural concepts; the PSP describes a product that uses design or safety assurance concepts considered... the end of the system design review phase of product development and 180 days prior to planned implementation, inviting FRA to participate in the design review process and receive periodic briefings and...

49 CFR 236.913 - Filing and approval of PSPs.

Code of Federal Regulations, 2010 CFR

2010-10-01

... architectural concepts; the PSP describes a product that uses design or safety assurance concepts considered... the end of the system design review phase of product development and 180 days prior to planned implementation, inviting FRA to participate in the design review process and receive periodic briefings and...

Designing Creative User Interactions for Learning

ERIC Educational Resources Information Center

Hong, Yi-Chun; Clinton, Gregory; Rieber, Lloyd P.

2014-01-01

Profitable creative ideas can emerge from within virtually any phase of the instructional design and development process. However, the design of user interactions is perhaps where learners can most directly experience the benefits of such ideas. In this article, the authors discuss principles of learner interaction as found in the instructional…

Leader Noticing of Facilitation in Videocases of Mathematics Professional Development

ERIC Educational Resources Information Center

Lesseig, Kristin; Elliott, Rebekah; Kazemi, Elham; Kelley-Petersen, Megan; Campbell, Matthew; Mumme, Judith; Carroll, Cathy

2017-01-01

In this article, we report on "Researching Mathematics Leader Learning" ("RMLL"), a project designed to support leaders in learning how to facilitate robust opportunities for teachers' mathematical learning. Our two-phase research design allowed us to construct a set of videocase seminars, enact the seminar design with leaders,…

Ergonomic risk assessment with DesignCheck to evaluate assembly work in different phases of the vehicle development process.

PubMed

Winter, Gabriele; Schaub, Karlheinz G; Großmann, Kay; Laun, Gerhard; Landau, Kurt; Bruder, Ralph

2012-01-01

Occupational hazards exist, if the design of the work situation is not in accordance with ergonomic design principles. At assembly lines ergonomics is applied to the design of work equipment and tasks and to work organisation. The ignoring of ergonomic principles in planning and design of assembly work leads to unfavourable working posture, action force and material handling. Disorders of the musculoskeletal system are of a common occurrence throughout Europe. Musculoskeletal disorders are a challenge against the background of disabled workers. The changes in a worker's capability have to be regarded in the conception of redesigned and new assembly lines. In this way ergonomics becomes progressively more important in planning and design of vehicles: The objective of ergonomic design in different stages of the vehicles development process is to achieve an optimal adaptation of the assembly work to workers. Hence the ergonomic screening tool "Design Check" (DC) was developed to identify ergonomic deficits in workplace layouts. The screening-tool is based on the current ergonomic state of the art in the design of physical work and relevant EU legal requirements. It was tested within a federal German research project at selected work stations at the assembly lines at Dr.-Ing. h.c. F. Porsche AG / Stuttgart. Meanwhile the application of the screening-tool DC is transferred in other parts of the Porsche AG, Stuttgart. It is also realized as an ergonomic standard method to perform assembly work in different phases of the vehicle development process.

Next Generation Solar Collectors for CSP

DOE Office of Scientific and Technical Information (OSTI.GOV)

Molnar, Attila; Charles, Ruth

The intent of “Next Generation Solar Collectors for CSP” program was to develop key technology elements for collectors in Phase 1 (Budget Period 1), design these elements in Phase 2 (Budget Period 2) and to deploy and test the final collector in Phase 3 (Budget Period 3). 3M and DOE mutually agreed to terminate the program at the end of Budget Period 1, primarily due to timeline issues. However, significant advancements were achieved in developing a next generation reflective material and panel that has the potential to significantly improve the efficiency of CSP systems.

Experimental clean combustor program, phase 2

NASA Technical Reports Server (NTRS)

Gleason, C. C.; Rogers, D. W.; Bahr, D. W.

1976-01-01

The primary objectives of this three-phase program are to develop technology for the design of advanced combustors with significantly lower pollutant emission levels than those of current combustors, and to demonstrate these pollutant emission reductions in CF6-50C engine tests. The purpose of the Phase 2 Program was to further develop the two most promising concepts identified in the Phase 1 Program, the double annular combustor and the radial/axial staged combustor, and to design a combustor and breadboard fuel splitter control for CF6-50 engine demonstration testing in the Phase 3 Program. Noise measurement and alternate fuels addendums to the basic program were conducted to obtain additional experimental data. Twenty-one full annular and fifty-two sector combustor configurations were evaluated. Both combustor types demonstrated the capability for significantly reducing pollutant emission levels. The most promising results were obtained with the double annular combustor. Rig test results corrected to CF-50C engine conditions produced EPA emission parameters for CO, HC, and NOX of 3.4, 0.4, and 4.5 respectively. These levels represent CO, HC, and NOX reductions of 69, 90, and 42 percent respectively from current combustor emission levels. The combustor also met smoke emission level requirements and development engine performance and installation requirements.

Phase Contrast Imaging on the HL-2A Tokamak

NASA Astrophysics Data System (ADS)

Yu, Yi; Gong, Shaobo; Xu, Min; Jiang, Wei; Zhong, Wulv; Shi, Zhongbin; Wang, Huajie; Wu, Yifan; Yuan, Boda; Lan, Tao; Ye, Minyou; Duan, Xuru; HL-2A Team

2016-10-01

In this article we present the design of a phase contrast imaging (PCI) system on the HL-2A tokamak. This diagnostic is developed to infer line integrated plasma density fluctuations by measuring the phase shift of an expanded CO2 laser beam passing through magnetically confined high temperature plasmas. This system is designed to diagnose plasma density fluctuations with the maximum wavenumber of 66 cm-1. The designed wavenumber resolution is 2.09cm-1, and the time resolution is higher than 0.2 μs. The broad kρs ranging from 0.34 to 13.37 makes it suitable for turbulence measurement. An upgraded PCI system is also discussed, which is designed for the HL-2M tokamak. Supported by the National Magnetic Confinement Fusion Energy Research Project (Grant No. 2015GB120002), the National Natural Science Foundation of China (Grant No. 11375053, 11105144, 10905057, 11535013).

Strategies for Time-resolved X-ray Diffraction of Phase Transitions with Laser Compression

NASA Astrophysics Data System (ADS)

Benedetti, Laura Robin; Eggert, J. H.; Bradley, D. K.; Bell, P. M.; Kilkenny, J. D.; Palmer, N.; Petre, R. B.; Rygg, J. R.; Sorce, C.; Collins, G. W.; Boehly, T. R.

2017-10-01

As part of a program to document kinetics of phase transitions under laser-driven dynamic compression, we are designing a platform to make multiple x-ray diffraction measurements during a single laser experiment. Our plans include experimental development at Omega-EP and eventual implementation at NIF. We will present our strategy for designing a robust platform that can effectively document a wide variety of phase transformations by utilizing both streaked and multiple-frame imaging detectors. Preliminary designs utilize a novel CMOS detector designed by Sandia National Lab. Our initial experiments include scoping studies that will focus on photometrics and shielding requirements in the high EMP environment close to the target. This work was performed under the auspices of the U.S. Department of Energy by Lawrence Livermore National Laboratory under Contract DE-AC52-07NA27344. Lawrence Livermore National Security, LLC, LLNL-ABS-734470.

Developing an Inflatable Solar Array

NASA Technical Reports Server (NTRS)

Malone, Patrick K.; Jankowski, Francis J.; Williams, Geoffery T.; Vendura, George J., Jr.

1992-01-01

Viewgraphs describing the development of an inflatable solar array as part of the Inflatable Torus Solar Array Technology (ITSAT) program are presented. Program phases, overall and subsystem designs, and array deployment are addressed.

Using Analytics to Transform a Problem-Based Case Library: An Educational Design Research Approach

ERIC Educational Resources Information Center

Schmidt, Matthew; Tawfik, Andrew A.

2018-01-01

This article describes the iterative design, development, and evaluation of a case-based learning environment focusing on an ill-structured sales management problem. We discuss our processes and situate them within the broader framework of educational design research. The learning environment evolved over the course of three design phases. A…

Designing eHealth that Matters via a Multidisciplinary Requirements Development Approach

PubMed Central

Wentzel, Jobke; Van Gemert-Pijnen, Julia EWC

2013-01-01

Background Requirements development is a crucial part of eHealth design. It entails all the activities devoted to requirements identification, the communication of requirements to other developers, and their evaluation. Currently, a requirements development approach geared towards the specifics of the eHealth domain is lacking. This is likely to result in a mismatch between the developed technology and end user characteristics, physical surroundings, and the organizational context of use. It also makes it hard to judge the quality of eHealth design, since it makes it difficult to gear evaluations of eHealth to the main goals it is supposed to serve. Objective In order to facilitate the creation of eHealth that matters, we present a practical, multidisciplinary requirements development approach which is embedded in a holistic design approach for eHealth (the Center for eHealth Research roadmap) that incorporates both human-centered design and business modeling. Methods Our requirements development approach consists of five phases. In the first, preparatory, phase the project team is composed and the overall goal(s) of the eHealth intervention are decided upon. Second, primary end users and other stakeholders are identified by means of audience segmentation techniques and our stakeholder identification method. Third, the designated context of use is mapped and end users are profiled by means of requirements elicitation methods (eg, interviews, focus groups, or observations). Fourth, stakeholder values and eHealth intervention requirements are distilled from data transcripts, which leads to phase five, in which requirements are communicated to other developers using a requirements notation template we developed specifically for the context of eHealth technologies. Results The end result of our requirements development approach for eHealth interventions is a design document which includes functional and non-functional requirements, a list of stakeholder values, and end user profiles in the form of personas (fictitious end users, representative of a primary end user group). Conclusions The requirements development approach presented in this article enables eHealth developers to apply a systematic and multi-disciplinary approach towards the creation of requirements. The cooperation between health, engineering, and social sciences creates a situation in which a mismatch between design, end users, and the organizational context can be avoided. Furthermore, we suggest to evaluate eHealth on a feature-specific level in order to learn exactly why such a technology does or does not live up to its expectations. PMID:23796508

The Development of SCORM-Conformant Learning Content Based on the Learning Cycle Using Participatory Design

ERIC Educational Resources Information Center

Su, C. Y.; Chiu, C. H.; Wang, T. I.

2010-01-01

This study incorporates the 5E learning cycle strategy to design and develop Sharable Content Object Reference Model-conformant materials for elementary science education. The 5E learning cycle that supports the constructivist approach has been widely applied in science education. The strategy consists of five phases: engagement, exploration,…

Near-term hybrid vehicle program, phase 1. Appendix B: Design trade-off studies report. Volume 3: Computer program listings

NASA Technical Reports Server (NTRS)

1979-01-01

A description and listing is presented of two computer programs: Hybrid Vehicle Design Program (HYVELD) and Hybrid Vehicle Simulation Program (HYVEC). Both of the programs are modifications and extensions of similar programs developed as part of the Electric and Hybrid Vehicle System Research and Development Project.

Balloon-borne three-meter telescope for far-infrared and submillimeter astronomy

NASA Technical Reports Server (NTRS)

Fazio, Giovanni G.; Hoffmann, William F.; Harper, Doyal A.

1988-01-01

The scientific objectives, engineering analysis and design, results of technology development, and focal-plane instrumentation for a two-meter balloon-borne telescope for far-infrared and submillimeter astronomy are presented. The unique capabilities of balloon-borne observations are discussed. A program summary emphasizes the development of the two-meter design. The relationship of the Large Deployable Reflector (LDR) is also discussed. Detailed treatment is given to scientific objectives, gondola design, the mirror development program, experiment accommodations, ground support equipment requirements, NSBF design drivers and payload support requirements, the implementation phase summary development plan, and a comparison of three-meter and two-meter gondola concepts.

Recent developments in the structural design and optimization of ITER neutral beam manifold

NASA Astrophysics Data System (ADS)

Chengzhi, CAO; Yudong, PAN; Zhiwei, XIA; Bo, LI; Tao, JIANG; Wei, LI

2018-02-01

This paper describes a new design of the neutral beam manifold based on a more optimized support system. A proposed alternative scheme has presented to replace the former complex manifold supports and internal pipe supports in the final design phase. Both the structural reliability and feasibility were confirmed with detailed analyses. Comparative analyses between two typical types of manifold support scheme were performed. All relevant results of mechanical analyses for typical operation scenarios and fault conditions are presented. Future optimization activities are described, which will give useful information for a refined setting of components in the next phase.

Design of a Bayesian adaptive phase 2 proof-of-concept trial for BAN2401, a putative disease-modifying monoclonal antibody for the treatment of Alzheimer's disease.

PubMed

Satlin, Andrew; Wang, Jinping; Logovinsky, Veronika; Berry, Scott; Swanson, Chad; Dhadda, Shobha; Berry, Donald A

2016-01-01

Recent failures in phase 3 clinical trials in Alzheimer's disease (AD) suggest that novel approaches to drug development are urgently needed. Phase 3 risk can be mitigated by ensuring that clinical efficacy is established before initiating confirmatory trials, but traditional phase 2 trials in AD can be lengthy and costly. We designed a Bayesian adaptive phase 2, proof-of-concept trial with a clinical endpoint to evaluate BAN2401, a monoclonal antibody targeting amyloid protofibrils. The study design used dose response and longitudinal modeling. Simulations were used to refine study design features to achieve optimal operating characteristics. The study design includes five active treatment arms plus placebo, a clinical outcome, 12-month primary endpoint, and a maximum sample size of 800. The average overall probability of success is ≥80% when at least one dose shows a treatment effect that would be considered clinically meaningful. Using frequent interim analyses, the randomization ratios are adapted based on the clinical endpoint, and the trial can be stopped for success or futility before full enrollment. Bayesian statistics can enhance the efficiency of analyzing the study data. The adaptive randomization generates more data on doses that appear to be more efficacious, which can improve dose selection for phase 3. The interim analyses permit stopping as soon as a predefined signal is detected, which can accelerate decision making. Both features can reduce the size and duration of the trial. This study design can mitigate some of the risks associated with advancing to phase 3 in the absence of data demonstrating clinical efficacy. Limitations to the approach are discussed.

Continued Water-Based Phase Change Material Heat Exchanger Development

NASA Technical Reports Server (NTRS)

Hansen, Scott; Poynot, Joe

2014-01-01

In a cyclical heat load environment such as low Lunar orbit, a spacecraft's radiators are not sized to reject the full heat load requirement. Traditionally, a supplemental heat rejection device (SHReD) such as an evaporator or sublimator is used to act as a "topper" to meet the additional heat rejection demands. Utilizing a Phase Change Material (PCM) heat exchanger (HX) as a SHReD provides an attractive alternative to evaporators and sublimators as PCM HXs do not use a consumable, thereby leading to reduced launch mass and volume requirements. In continued pursuit of water PCM HX development two full-scale, Orion sized water-based PCM HX's were constructed by Mezzo Technologies. These HX's were designed by applying prior research and experimentation to the full scale design. Design options considered included bladder restraint and clamping mechanisms, bladder manufacturing, tube patterns, fill/drain methods, manifold dimensions, weight optimization, and midplate designs. Design and construction of these HX's led to successful testing of both PCM HX's.

Developing a Free-Piston Stirling Convertor for advanced radioisotope space power systems

NASA Astrophysics Data System (ADS)

Qiu, Songgang; Augenblick, John E.; White, Maurice A.; Peterson, Allen A.; Redinger, Darin L.; Petersen, Stephen L.

2002-01-01

The Department of Energy (DOE) has selected Free-Piston Stirling Convertors as a technology for future advanced radioisotope space power systems. In August 2000, DOE awarded competitive Phase I, Stirling Radioisotope Generator (SRG) power system integration contracts to three major aerospace contractors, resulting in SRG conceptual designs in February 2001. All three contractors based their designs on the Technology Demonstration Convertor (TDC) developed by Stirling Technology Company (STC) for DOE. The contract award to a single system integration contractor for Phases II and III of the SRG program is anticipated in late 2001. The first potential SRG mission is targeted for a Mars rover. This paper provides a description of the Flight Prototype (FP) Stirling convertor design as compared to the previous TDC design. The initial flight prototype units are already undergoing performance tuning at STC. The new design will be hermetically scaled and will provide a weight reduction from approximately 4.8 kg to approximately 3.9 kg. .

Guidance, Navigation and Control (GN&C): Best Practices for Human-Rated Spacecraft Systems

NASA Technical Reports Server (NTRS)

Lebsock, Ken; West, John

2008-01-01

In 2007 the NESC completed an in-depth assessment to identify, define and document engineering considerations for the Design Development Test and Evaluation (DDT&E) of human-rated spacecraft systems. This study had been requested by the Astronaut Office at JSC to help them to better understand what is required to ensure safe, robust, and reliable human-rated spacecraft systems. The 22 GN&C engineering Best Practices described in this paper are a condensed version of what appears in the NESC Technical Report. These Best Practices cover a broad range from fundamental system architectural considerations to more specific aspects (e.g., stability margin recommendations) of GN&C system design and development. 15 of the Best Practices address the early phases of a GN&C System development project and the remaining 7 deal with the later phases. Some of these Best Practices will cross-over between both phases. We recognize that this set of GN&C Best Practices will not be universally applicable to all projects and mission applications.

Final Report - Enhanced LAW Glass Property - Composition Models - Phase 1 VSL-13R2940-1, Rev. 0, dated 9/27/2013

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kruger, Albert A.; Muller, I.; Gilbo, K.

2013-11-13

The objectives of this work are aimed at the development of enhanced LAW propertycomposition models that expand the composition region covered by the models. The models of interest include PCT, VHT, viscosity and electrical conductivity. This is planned as a multi-year effort that will be performed in phases with the objectives listed below for the current phase.  Incorporate property- composition data from the new glasses into the database.  Assess the database and identify composition spaces in the database that need augmentation.  Develop statistically-designed composition matrices to cover the composition regions identified in the above analysis.  Preparemore » crucible melts of glass compositions from the statistically-designed composition matrix and measure the properties of interest.  Incorporate the above property-composition data into the database.  Assess existing models against the complete dataset and, as necessary, start development of new models.« less

Engineering approaches and compromises in the design of small ion mobility spectrometers

NASA Technical Reports Server (NTRS)

Bradshaw, R. F. D.

1995-01-01

The engineering approaches in the design phase of small portable I.M.S.-based instruments are discussed. The choices available are described, and their effect on instrument dimensions analyzed. Possible future developments are outlined.

Bio-based renewable additives for anti-icing applications (phase one).

DOT National Transportation Integrated Search

2016-09-04

The performance and impacts of several bio-based anti-icers along with a traditional chloride-based anti-icer (salt brine) were evaluated. : A statistical design of experiments (uniform design) was employed for developing anti-icing liquids consistin...

Development and Optimization of HPLC Analysis of Metronidazole, Diloxanide, Spiramycin and Cliquinol in Pharmaceutical Dosage Forms Using Experimental Design.

PubMed

Elkhoudary, Mahmoud M; Abdel Salam, Randa A; Hadad, Ghada M

2016-11-01

A new simple, sensitive, rapid and accurate gradient reversed-phase high-performance liquid chromatography with photodiode array detector (RP-HPLC-DAD) was developed and validated for simultaneous analysis of Metronidazole (MNZ), Spiramycin (SPY), Diloxanidefuroate (DIX) and Cliquinol (CLQ) using statistical experimental design. Initially, a resolution V fractional factorial design was used in order to screen five independent factors: the column temperature (°C), pH, phosphate buffer concentration (mM), flow rate (ml/min) and the initial fraction of mobile phase B (%). pH, flow rate and initial fraction of mobile phase B were identified as significant, using analysis of variance. The optimum conditions of separation determined with the aid of central composite design were: (1) initial mobile phase concentration: phosphate buffer/methanol (50/50, v/v), (2) phosphate buffer concentration (50 mM), (3) pH (4.72), (4) column temperature 30°C and (5) mobile phase flow rate (0.8 ml min -1 ). Excellent linearity was observed for all of the standard calibration curves, and the correlation coefficients were above 0.9999. Limits of detection for all of the analyzed compounds ranged between 0.02 and 0.11 μg ml -1 ; limits of quantitation ranged between 0.06 and 0.33 μg ml -1 The proposed method showed good prediction ability. The optimized method was validated according to ICH guidelines. Three commercially available tablets were analyzed showing good % recovery and %RSD. © The Author 2016. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

Exploratory Development Research of U.S. Navy Marine Corps Personnel, Phase 1. Factors Affecting Attrition

DTIC Science & Technology

1977-09-30

havior. He has taught courses in research and has had con- siderable experience in the design and analysis of qualitative and quantitative research...name, serial number, unit, rank, or other identifying information was asked. Research pesign The research design was developed to determine if causes of...attrition have similar impach on men in various situations. The design includes three principal components. First, both attriters and adjusted men

Seneca Compressed Air Energy Storage (CAES) Project

DOE Office of Scientific and Technical Information (OSTI.GOV)

None, None

2012-11-30

Compressed Air Energy Storage (CAES) is a hybrid energy storage and generation concept that has many potential benefits especially in a location with increasing percentages of intermittent wind energy generation. The objectives of the NYSEG Seneca CAES Project included: for Phase 1, development of a Front End Engineering Design for a 130MW to 210 MW utility-owned facility including capital costs; project financials based on the engineering design and forecasts of energy market revenues; design of the salt cavern to be used for air storage; draft environmental permit filings; and draft NYISO interconnection filing; for Phase 2, objectives included plant constructionmore » with a target in-service date of mid-2016; and for Phase 3, objectives included commercial demonstration, testing, and two-years of performance reporting. This Final Report is presented now at the end of Phase 1 because NYSEG has concluded that the economics of the project are not favorable for development in the current economic environment in New York State. The proposed site is located in NYSEG’s service territory in the Town of Reading, New York, at the southern end of Seneca Lake, in New York State’s Finger Lakes region. The landowner of the proposed site is Inergy, a company that owns the salt solution mining facility at this property. Inergy would have developed a new air storage cavern facility to be designed for NYSEG specifically for the Seneca CAES project. A large volume, natural gas storage facility owned and operated by Inergy is also located near this site and would have provided a source of high pressure pipeline quality natural gas for use in the CAES plant. The site has an electrical take-away capability of 210 MW via two NYSEG 115 kV circuits located approximately one half mile from the plant site. Cooling tower make-up water would have been supplied from Seneca Lake. NYSEG’s engineering consultant WorleyParsons Group thoroughly evaluated three CAES designs and concluded that any of the designs would perform acceptably. Their general scope of work included development of detailed project construction schedules, capital cost and cash flow estimates for both CAES cycles, and development of detailed operational data, including fuel and compression energy requirements, to support dispatch modeling for the CAES cycles. The Dispatch Modeling Consultant selected for this project was Customized Energy Solutions (CES). Their general scope of work included development of wholesale electric and gas market price forecasts and development of a dispatch model specific to CAES technologies. Parsons Brinkerhoff Energy Storage Services (PBESS) was retained to develop an air storage cavern and well system design for the CAES project. Their general scope of work included development of a cavern design, solution mining plan, and air production well design, cost, and schedule estimates for the project. Detailed Front End Engineering Design (FEED) during Phase 1 of the project determined that CAES plant capital equipment costs were much greater than the $125.6- million originally estimated by EPRI for the project. The initial air storage cavern Design Basis was increased from a single five million cubic foot capacity cavern to three, five million cubic foot caverns with associated air production wells and piping. The result of this change in storage cavern Design Basis increased project capital costs significantly. In addition, the development time required to complete the three cavern system was estimated at approximately six years. This meant that the CAES plant would initially go into service with only one third of the required storage capacity and would not achieve full capability until after approximately five years of commercial operation. The market price forecasting and dispatch modeling completed by CES indicated that the CAES technologies would operate at only 10 to 20% capacity factors and the resulting overall project economics were not favorable for further development. As a result of all of these factors, the Phase 1 FEED developed an installed CAES plant cost estimate of approximately $2,300/KW for the 210MW CAES 1A and 2 cycles. The capital cost for the 136 MW CAES 1 cycle was even higher due to the lower generating capacity of the cycle. Notably, the large equipment could have generated additional capacity (up to 270MW) which would have improved the cost per KW; however, the output was limited by the night time transmission system capability. The research herein, therefore, is particular to the site-specific factors that influenced the design and the current and forecasted generation mix and energy prices in Upstate New York and may not necessarily indicate that CAES plants cannot be economically constructed in other places in New York State or the world.« less

A lunar base reference mission for the phased implementation of bioregenerative life support system components

NASA Technical Reports Server (NTRS)

Dittmer, Laura N.; Drews, Michael E.; Lineaweaver, Sean K.; Shipley, Derek E.; Hoehn, A.

1991-01-01

Previous design efforts of a cost effective and reliable regenerative life support system (RLSS) provided the foundation for the characterization of organisms or 'biological processors' in engineering terms and a methodology was developed for their integration into an engineered ecological LSS in order to minimize the mass flow imbalances between consumers and producers. These techniques for the design and the evaluation of bioregenerative LSS have now been integrated into a lunar base reference mission, emphasizing the phased implementation of components of such a BLSS. In parallel, a designers handbook was compiled from knowledge and experience gained during past design projects to aid in the design and planning of future space missions requiring advanced RLSS technologies. The lunar base reference mission addresses in particular the phased implementation and integration of BLS parts and includes the resulting infrastructure burdens and needs such as mass, power, volume, and structural requirements of the LSS. Also, operational aspects such as manpower requirements and the possible need and application of 'robotics' were addressed.

Design and Stability of an On-Orbit Attitude Control System Using Reaction Control Thrusters

NASA Technical Reports Server (NTRS)

Hall, Robert A.; Hough, Steven; Orphee, Carolina; Clements, Keith

2016-01-01

Basic principles for the design and stability of a spacecraft on-orbit attitude control system employing on-off Reaction Control System (RCS) thrusters are presented. Both vehicle dynamics and the control system actuators are inherently nonlinear, hence traditional linear control system design approaches are not directly applicable. This paper has two main aspects: It summarizes key RCS design principles from earlier NASA vehicles, notably the Space Shuttle and Space Station programs, and introduces advances in the linear modelling and analyses of a phase plane control system derived in the initial development of the NASA's next upper stage vehicle, the Exploration Upper Stage (EUS). Topics include thruster hardware specifications, phase plane design and stability, jet selection approaches, filter design metrics, and RCS rotational maneuver logic.

Development of the digital design environment ProjectWise(TM) - phase 1.

DOT National Transportation Integrated Search

2017-04-28

The goal of this research was to develop a project document management system capable of managing : Connecticut Department of Transportation (CTDOT) Capital Road and Bridge Program. Primary targets of : research and development included the system, c...

Mobile Food Ordering Application using Android OS Platform

NASA Astrophysics Data System (ADS)

Yosep Ricky, Michael

2014-03-01

The purpose of this research is making an ordering food application based on Android with New Order, Order History, Restaurant Profile, Order Status, Tracking Order, and Setting Profile features. The research method used in this research is water model of System Development Life Cycle (SDLC) method with following phases: requirement definition, analyzing and determining the features needed in developing application and making the detail definition of each features, system and software design, designing the flow of developing application by using storyboard design, user experience design, Unified Modeling Language (UML) design, and database structure design, implementation an unit testing, making database and translating the result of designs to programming language code then doing unit testing, integration and System testing, integrating unit program to one unit system then doing system testing, operation and maintenance, operating the result of system testing and if any changes and reparations needed then the previous phases could be back. The result of this research is an ordering food application based on Android for customer and courier user, and a website for restaurant and admin user. The conclusion of this research is to help customer in making order easily, to give detail information needed by customer, to help restaurant in receiving order, and to help courier while doing delivery.

Monolithic GaAs dual-gate FET phase shifter

NASA Astrophysics Data System (ADS)

Kumar, M.; Subbarao, S. N.; Menna, R.

1981-09-01

The objective of this program is to develop a monolithic GaAs dual-gate FET phase shifter, operating over the 4- to 8-GHz frequency band and capable of a continuously programmable phase shift from 0 deg through N times 360 deg where N is an integer. The phase shift is to be controllable to within +3 deg. This phase shifter will be capable of delivering an output power up to 0 dBm with an input and output VSWR of less than 1.5:1. Progress 1: The photomask of a 0 to 90 deg monolithic GaAs dual-gate FET phase shifter has been procured, and we are in the process of fabricating the phase shifter. 2: We have designed and fabricated a 50 ohm, 4-line interdigitated coupler. Also, we have designed and fabricated a 25-ohm, 6-line interdigitated coupler. The performance of both couplers agrees quite well with the theoretical results. Technical Problems: there was no major problem during this period.

Toward Phase IV, Populating the WOVOdat Database

NASA Astrophysics Data System (ADS)

Ratdomopurbo, A.; Newhall, C. G.; Schwandner, F. M.; Selva, J.; Ueda, H.

2009-12-01

One of challenges for volcanologists is the fact that more and more people are likely to live on volcanic slopes. Information about volcanic activity during unrest should be accurate and rapidly distributed. As unrest may lead to eruption, evacuation may be necessary to minimize damage and casualties. The decision to evacuate people is usually based on the interpretation of monitoring data. Over the past several decades, monitoring volcanoes has used more and more sophisticated instruments. A huge volume of data is collected in order to understand the state of activity and behaviour of a volcano. WOVOdat, The World Organization of Volcano Observatories (WOVO) Database of Volcanic Unrest, will provide context within which scientists can interpret the state of their own volcano, during and between crises. After a decision during the 2000 IAVCEI General Assembly to create WOVOdat, development has passed through several phases, from Concept Development (Phase-I in 2000-2002), Database Design (Phase-II, 2003-2006) and Pilot Testing (Phase-III in 2007-2008). For WOVOdat to be operational, there are still two (2) steps to complete, which are: Database Population (Phase-IV) and Enhancement and Maintenance (Phase-V). Since January 2009, the WOVOdat project is hosted by Earth Observatory of Singapore for at least a 5-year period. According to the original planning in 2002, this 5-year period will be used for completing the Phase-IV. As the WOVOdat design is not yet tested for all types of data, 2009 is still reserved for building the back-end relational database management system (RDBMS) of WOVOdat and testing it with more complex data. Fine-tuning of the WOVOdat’s RDBMS design is being done with each new upload of observatory data. The next and main phase of WOVOdat development will be data population, managing data transfer from multiple observatory formats to WOVOdat format. Data population will depend on two important things, the availability of SQL database in volcano observatories and their data sharing policy. Hence, a strong collaboration with every WOVO observatory is important. For some volcanoes where the data are not in an SQL system, the WOVOdat project will help scientists working on the volcano to start building an SQL database.

CAPS Simulation Environment Development

NASA Technical Reports Server (NTRS)

Murphy, Douglas G.; Hoffman, James A.

2005-01-01

The final design for an effective Comet/Asteroid Protection System (CAPS) will likely come after a number of competing designs have been simulated and evaluated. Because of the large number of design parameters involved in a system capable of detecting an object, accurately determining its orbit, and diverting the impact threat, a comprehensive simulation environment will be an extremely valuable tool for the CAPS designers. A successful simulation/design tool will aid the user in identifying the critical parameters in the system and eventually allow for automatic optimization of the design once the relationships of the key parameters are understood. A CAPS configuration will consist of space-based detectors whose purpose is to scan the celestial sphere in search of objects likely to make a close approach to Earth and to determine with the greatest possible accuracy the orbits of those objects. Other components of a CAPS configuration may include systems for modifying the orbits of approaching objects, either for the purpose of preventing a collision or for positioning the object into an orbit where it can be studied or used as a mineral resource. The Synergistic Engineering Environment (SEE) is a space-systems design, evaluation, and visualization software tool being leveraged to simulate these aspects of the CAPS study. The long-term goal of the SEE is to provide capabilities to allow the user to build and compare various CAPS designs by running end-to-end simulations that encompass the scanning phase, the orbit determination phase, and the orbit modification phase of a given scenario. Herein, a brief description of the expected simulation phases is provided, the current status and available features of the SEE software system is reported, and examples are shown of how the system is used to build and evaluate a CAPS detection design. Conclusions and the roadmap for future development of the SEE are also presented.

Low cost label-free live cell imaging for biological samples

NASA Astrophysics Data System (ADS)

Seniya, C.; Towers, C. E.; Towers, D. P.

2017-02-01

This paper reports the progress to develop a practical phase measuring microscope offering new capabilities in terms of phase measurement accuracy and quantification of cell:cell interactions over the longer term. A novel, low cost phase interference microscope for imaging live cells (label-free) is described. The method combines the Zernike phase contrast approach with a dual mirror design to enable phase modulation between the scattered and un-scattered optical fields. Two designs are proposed and demonstrated, one of which retains the common path nature of Zernike's original microscopy concept. In both setups the phase shift is simple to control via a piezoelectric driven mirror in the back focal plane of the imaging system. The approach is significantly cheaper to implement than those based on spatial light modulators (SLM) at approximately 20% of the cost. A quantitative assessment of the performance of a set of phase shifting algorithms is also presented, specifically with regard to broad bandwidth illumination in phase contrast microscopy. The simulation results show that the phase measurement accuracy is strongly dependent on the algorithm selected and the optical path difference in the sample.

Optics Design for the U.S. SKA Technology Development Project Design Verification Antenna

NASA Technical Reports Server (NTRS)

Imbriale, W. A.; Baker, L.; Cortes-Medellin, G.

2012-01-01

The U.S. design concept for the Square Kilometer Array (SKA) program is based on utilizing a large number of 15 meter dish antennas. The Technology Development Project (TDP) is planning to design and build the first of these antennas to provide a demonstration of the technology and a solid base on which to estimate costs. This paper describes the performance of the selected optics design. It is a dual-shaped offset Gregorian design with a feed indexer that can accommodate corrugated horns, wide band single pixel feeds or phased array feeds.

Problem Solving Model for Science Learning

NASA Astrophysics Data System (ADS)

Alberida, H.; Lufri; Festiyed; Barlian, E.

2018-04-01

This research aims to develop problem solving model for science learning in junior high school. The learning model was developed using the ADDIE model. An analysis phase includes curriculum analysis, analysis of students of SMP Kota Padang, analysis of SMP science teachers, learning analysis, as well as the literature review. The design phase includes product planning a science-learning problem-solving model, which consists of syntax, reaction principle, social system, support system, instructional impact and support. Implementation of problem-solving model in science learning to improve students' science process skills. The development stage consists of three steps: a) designing a prototype, b) performing a formative evaluation and c) a prototype revision. Implementation stage is done through a limited trial. A limited trial was conducted on 24 and 26 August 2015 in Class VII 2 SMPN 12 Padang. The evaluation phase was conducted in the form of experiments at SMPN 1 Padang, SMPN 12 Padang and SMP National Padang. Based on the development research done, the syntax model problem solving for science learning at junior high school consists of the introduction, observation, initial problems, data collection, data organization, data analysis/generalization, and communicating.

Definition of technology development missions for early space stations. Large space structures, phase 2, midterm review

NASA Technical Reports Server (NTRS)

1984-01-01

The large space structures technology development missions to be performed on an early manned space station was studied and defined and the resources needed and the design implications to an early space station to carry out these large space structures technology development missions were determined. Emphasis is being placed on more detail in mission designs and space station resource requirements.

A tactile paging system for deaf-blind people, phase 2

NASA Technical Reports Server (NTRS)

Baer, J. A.

1977-01-01

Control logic and the on-body radio transmitter is investigated. The control logic capability and studied methods for implementing the on-body portion of the logic in a small package are improved. A small low power, on-body transmitter was designed, developed, and tested with a wrist-strap antenna to extend the one-way communication system developed during Phase 1 to a two-way communication system.