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Sample records for detailed structural measurements

  1. Aircraft empennage structural detail design

    NASA Technical Reports Server (NTRS)

    Meholic, Greg; Brown, Rhonda; Hall, Melissa; Harvey, Robert; Singer, Michael; Tella, Gustavo

    1993-01-01

    This project involved the detailed design of the aft fuselage and empennage structure, vertical stabilizer, rudder, horizontal stabilizer, and elevator for the Triton primary flight trainer. The main design goals under consideration were to illustrate the integration of the control systems devices used in the tail surfaces and their necessary structural supports as well as the elevator trim, navigational lighting system, electrical systems, tail-located ground tie, and fuselage/cabin interface structure. Accommodations for maintenance, lubrication, adjustment, and repairability were devised. Weight, fabrication, and (sub)assembly goals were addressed. All designs were in accordance with the FAR Part 23 stipulations for a normal category aircraft.

  2. Aircraft empennage structural detail design

    NASA Technical Reports Server (NTRS)

    Lesnewski, David; Snow, Russ M.; Combs, Lisa M.; Paufler, David; Schnieder, George; Athousake, Roxanne

    1993-01-01

    The purpose of this project is to provide an empennage structural assembly that will withstand the operational loads defined in FAR Part 23, as well as those specified in the statement of work, i.e. snow, rain, humidity, tiedown forces, etc. The goal is to provide a simple yet durable lightweight structure that will transfer the aerodynamic forces produced by the tail surfaces through the most efficient load path to the airframe. The structure should be simple and cost-effective to manufacture and repair. All structures meet or exceed loading and fatigue criteria. The structure provides for necessary stiffness and ease of maintenance.

  3. Aircraft wing structure detail design

    NASA Technical Reports Server (NTRS)

    Sager, Garrett L.; Roberts, Ron; Mallon, Bob; Alameri, Mohamed; Steinbach, Bill

    1993-01-01

    The provisions of this project call for the design of the structure of the wing and carry-through structure for the Viper primary trainer, which is to be certified as a utility category trainer under FAR part 23. The specific items to be designed in this statement of work were Front Spar, Rear Spar, Aileron Structure, Wing Skin, and Fuselage Carry-through Structure. In the design of these parts, provisions for the fuel system, electrical system, and control routing were required. Also, the total weight of the entire wing planform could not exceed 216 lbs. Since this aircraft is to be used as a primary trainer, and the SOW requires a useful life of 107 cycles, it was decided that all of the principle stresses in the structural members would be kept below 10 ksi. The only drawback to this approach is a weight penalty.

  4. Detailed scour measurements around a debris accumulation

    USGS Publications Warehouse

    Mueller, David S.; Parola, Arthur C.

    1998-01-01

    Detailed scour measurements were made at Farm-Market 2004 over the Brazos River near Lake Jackson, Tex. during flooding in October 1994. Woody debris accumulations on bents 6, 7, and 8 obstructed flow through the bridge, causing scour of the streambed. Measurements at the site included three-dimensional velocities, channel bathymetry, water-surface elevations, water-surface slope, and discharge. Channel geometry upstream from the bridge caused approach conditions to be nonuniform.

  5. Instrumentation for detailed bridge-scour measurements

    USGS Publications Warehouse

    Landers, Mark N.; Mueller, David S.; Trent, Roy E.; ,

    1993-01-01

    A portable instrumentation system is being developed to obtain channel bathymetry during floods for detailed bridge-scour measurements. Portable scour measuring systems have four components: sounding instrument, horizontal positioning instrument, deployment mechanisms, and data storage device. The sounding instrument will be a digital fathometer. Horizontal position will be measured using a range-azimuth based hydrographic survey system. The deployment mechanism designed for this system is a remote-controlled boat using a small waterplane area, twin-hull design. An on-board computer and radio will monitor the vessel instrumentation, record measured data, and telemeter data to shore.

  6. The details of structural disconnectivity in psychotic disorder: A family-based study of non-FA diffusion weighted imaging measures.

    PubMed

    Michielse, Stijn; Gronenschild, Ed; Domen, Patrick; van Os, Jim; Marcelis, Machteld

    2017-09-15

    Diffusion tensor imaging (DTI) studies in psychotic disorder have shown reduced FA, often interpreted as disturbed white matter integrity. The observed 'dysintegrity' may be of multifactorial origin, as changes in FA are thought to reflect a combination of changes in myelination, fiber organization and number of axons. Examining the structural substrate of the diffusion tensor in individuals with (risk for) psychotic disorder may provide better understanding of the underlying structural changes. DTI scans were acquired from 85 patients with psychotic disorder, 93 siblings of patients with psychotic disorder and 80 controls. Cross-sectional group comparisons were performed using Tract-Based Spatial Statistics (TBSS) on six DTI measures: axial diffusivity (AXD), radial diffusivity (RD), mean diffusivity (MD), and the case linear (CL), case planar (CP) and case spherical (CS) tensor shape measures. AXD did not differ between the groups. RD and CS values were significantly increased in patients compared to controls and siblings, with no significant differences between the latter two groups. MD was higher in patients compared to controls (but not siblings), with no difference between siblings and controls. CL was smaller in patients than in siblings and controls, and CP was smaller in both patients and siblings as compared to controls. The differences between individuals with psychotic disorder and healthy controls, derived from detailed diffusion data analyses, suggest less fiber orientation and increased free water movement in the patients. There was some evidence for association with familial risk expressed by decreased fiber orientation. Copyright © 2017 Elsevier B.V. All rights reserved.

  7. Detailed Aerosol Characterization using Polarimetric Measurements

    NASA Astrophysics Data System (ADS)

    Hasekamp, Otto; di Noia, Antonio; Stap, Arjen; Rietjens, Jeroen; Smit, Martijn; van Harten, Gerard; Snik, Frans

    2016-04-01

    Anthropogenic aerosols are believed to cause the second most important anthropogenic forcing of climate change after greenhouse gases. In contrast to the climate effect of greenhouse gases, which is understood relatively well, the negative forcing (cooling effect) caused by aerosols represents the largest reported uncertainty in the most recent assessment of the International Panel on Climate Change (IPCC). To reduce the large uncertainty on the aerosol effects on cloud formation and climate, accurate satellite measurements of aerosol optical properties (optical thickness, single scattering albedo, phase function) and microphysical properties (size distribution, refractive index, shape) are essential. There is growing consensus in the aerosol remote sensing community that multi-angle measurements of intensity and polarization are essential to unambiguously determine all relevant aerosol properties. This presentations adresses the different aspects of polarimetric remote sensing of atmospheric aerosols, including retrieval algorithm development, validation, and data needs for climate and air quality applications. During past years, at SRON-Netherlands Instite for Space Research retrieval algorithms have been developed that make full use of the capabilities of polarimetric measurements. We will show results of detailed aerosol properties from ground-based- (groundSPEX), airborne- (NASA Research Scanning Polarimeter), and satellite (POLDER) measurements. Also we will discuss observational needs for future instrumentation in order to improve our understanding of the role of aerosols in climate change and air quality.

  8. Structural concepts and details for seismic design

    SciTech Connect

    Not Available

    1991-09-01

    This manual discusses building and building component behavior during earthquakes, and provides suggested details for seismic resistance which have shown by experience to provide adequate performance during earthquakes. Special design and construction practices are also described which, although they might be common in some high-seismic regions, may not be common in low and moderate seismic-hazard regions of the United States. Special attention is given to describing the level of detailing appropriate for each seismic region. The UBC seismic criteria for all seismic zones is carefully examined, and many examples of connection details are given. The general scope of discussion is limited to materials and construction types common to Department of Energy (DOE) sites. Although the manual is primarily written for professional engineers engaged in performing seismic-resistant design for DOE facilities, the first two chapters, plus the introductory sections of succeeding chapters, contain descriptions which are also directed toward project engineers who authorize, review, or supervise the design and construction of DOE facilities. 88 refs., 188 figs.

  9. Structured detailed opto-mechanical tolerance modeling

    NASA Astrophysics Data System (ADS)

    Swart, P. C.

    2016-02-01

    Opto-mechanical tolerancing is a complex art, which is often reduced to inadequate tabled data of allowable tilts and decentres. During the process the respective roles of optical- and mechanical designers can become entangled and a source of conflict. A framework of principles is introduced to guide the design team through these murky waters. From these principles the development of a catalogue of models, practices and past precedents are proposed. An example is presented to serve as illustration. The final result is a model, of opto-mechanical tolerances, which allows a structured flow of tolerances into optical performance prediction.

  10. Interior detail of structural elements section; camera facing east. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Interior detail of structural elements section; camera facing east. - Mare Island Naval Shipyard, Supply Building, Walnut Avenue, southeast corner of Walnut Avenue & Fifth Street, Vallejo, Solano County, CA

  11. Structural details below roadway, looking north from south abutment. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Structural details below roadway, looking north from south abutment. - Pleasantville Covered Bridge, Spanning Little Manatawny Creek at Covered Bridge Road (State Route 1030), Manatawny, Berks County, PA

  12. Crack propagation modelling for high strength steel welded structural details

    NASA Astrophysics Data System (ADS)

    Mecséri, B. J.; Kövesdi, B.

    2017-05-01

    Nowadays the barrier of applying HSS (High Strength Steel) material in bridge structures is their low fatigue strength related to yield strength. This paper focuses on the fatigue behaviour of a structural details (a gusset plate connection) made from NSS and HSS material, which is frequently used in bridges in Hungary. An experimental research program is carried out at the Budapest University of Technology and Economics to investigate the fatigue lifetime of this structural detail type through the same test specimens made from S235 and S420 steel grades. The main aim of the experimental research program is to study the differences in the crack propagation and the fatigue lifetime between normal and high strength steel structures. Based on the observed fatigue crack pattern the main direction and velocity of the crack propagation is determined. In parallel to the tests finite element model (FEM) are also developed, which model can handle the crack propagation. Using the measured strain data in the tests and the calculated values from the FE model, the approximation of the material parameters of the Paris law are calculated step-by-step, and their calculated values are evaluated. The same material properties are determined for NSS and also for HSS specimens as well, and the differences are discussed. In the current paper, the results of the experiments, the calculation method of the material parameters and the calculated values are introduced.

  13. 31. View southeast from north side of structure noting detail ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    31. View southeast from north side of structure noting detail of Section 2 of the Metal Bent portion of the structure. - Augustine Bridge, Brandywine River,Augustine Cutoff, Wilmington, New Castle County, DE

  14. View south, wharf B, showing western docking structure, decking detail ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    View south, wharf B, showing western docking structure, decking detail - U.S. Coast Guard Sandy Hook Station, Western Docking Structure, West of intersection of Canfield Road & Hartshorne Drive, Highlands, Monmouth County, NJ

  15. INTERIOR; DETAIL OF ROOF FRAMING STRUCTURE, LOOKING SOUTHWEST. Naval ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    INTERIOR; DETAIL OF ROOF FRAMING STRUCTURE, LOOKING SOUTHWEST. - Naval Computer & Telecommunications Area Master Station, Eastern Pacific, Radio Transmitter Facility Lualualei, Helix House No. 2, Base of Radio Antenna Structure No. 427, Makaha, Honolulu County, HI

  16. 21. Photocopy of 1897 measured drawing showing details of Solitude. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    21. Photocopy of 1897 measured drawing showing details of Solitude. Delineators: Charles L. Hillman and John McClintock. Original at the Free Library of Philadelphia, Philadelphia, Pa. - Solitude, Zoo grounds, Philadelphia, Philadelphia County, PA

  17. 22. Photocopy of 1897 measured drawing showing details of Solitude. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    22. Photocopy of 1897 measured drawing showing details of Solitude. Delineators: Charles L. Hillman and John McClintock. Original at the Free Library of Philadelphia, Philadelphia, Pa. - Solitude, Zoo grounds, Philadelphia, Philadelphia County, PA

  18. 13. DETAIL SHOWING EXPOSED VERTICAL LOG CONSTRUCTION WITH MEASURING TAPE, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    13. DETAIL SHOWING EXPOSED VERTICAL LOG CONSTRUCTION WITH MEASURING TAPE, WEST ROOM AT REAR OF HOUSE, FIRST FLOOR - Pierre Delassus DeLuziereHouse, U.S. Route 61, Sainte Genevieve, Ste. Genevieve County, MO

  19. Mapping hydrogeophysical structures with time--domain electromagnetic methods: Resolving small-scale details with large loops and three--component measurements

    NASA Astrophysics Data System (ADS)

    Weiss, C. J.; Li, Y.; Nabighian, M.

    2004-12-01

    One of the outstanding problems in managing water resources in geologically complex aquifers is to develop improved techniques for mapping compartmentalization due to faulting. And although the role of faults in aquifer dynamics can vary considerably, knowledge of their location is key to understanding aquifer recharge and developing a sensible model for predicting aquifer response due to anthropogenic loads. We have explored the application of time--domain electromagnetic methods for mapping shallow aquifer faults on the western flanks of the Estancia Basin, central New Mexico. The field site is underlain by massive Pennsylvanian limestones (Madera Group) subsequently faulted by Laramide tectonics of the Ancestral Rockies and Neogene extension of the Rio Grande Rift. Two experimental configurations were deployed: a large 50 × 40 m transmitter loop with receiver stations located on a 5 m grid over the loop's interior; and an azimuthal survey consisting of a smaller fixed transmitter with receiver stations at ˜2 m intervals along a 30 m radius circle centered on the transmitter. Three--component transients of magnetic field due to a fast linear ramp--off in the transmitter were recorded at each station. As a rapid reconnaisance tool, the azimuthal experiment is well--suited for identification of subsurface fault planes since symmetry constraints require a vanishing azimuthal ̂ φ component of magnetic field when the electrical strike, or fault plane, lies in the ̂ φ direction. However, each of the experimental configurations revealed that the site's electrical structure is far more three--dimensional than previously believed and is not dominated by the response of a previously identified fault plane. Instead, we have observed spatially coherent transient signals which may indicate compartmentalization over length scales as small as a few tens of meters. Sections of this work were performed at Sandia National Laboratories. Sandia is a multi--program laboratory

  20. Detailed electrical measurements on sago starch biopolymer solid electrolyte

    NASA Astrophysics Data System (ADS)

    Singh, Rahul; Baghel, Jaya; Shukla, S.; Bhattacharya, B.; Rhee, Hee-Woo; Singh, Pramod K.

    2014-12-01

    The biopolymer solid electrolyte has been synthesized and characterized. Potassium iodide (KI) has been added in polymer matrix to develop solid polymer electrolyte. Relationships between electrical, ionic transport parameter and mechanism have been studied in detail. Impedance spectroscopy reveals the detailed electrical studies and ion transport mechanism. The ion dissociation factor is compared with a measured dielectric constant at a fixed frequency. The dielectric data are calculated which support the ionic conductivity data.

  1. 91. Virginia Route 608 grade separation structure. Detail of the ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    91. Virginia Route 608 grade separation structure. Detail of the scored wing walls and T beams. Looking southeast. - Blue Ridge Parkway, Between Shenandoah National Park & Great Smoky Mountains, Asheville, Buncombe County, NC

  2. Section A, detail view parking structure, northwest stair tower, showing ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Section A, detail view parking structure, northwest stair tower, showing smoke damage under floors, looking north/northeast. (BH) - World Trade Center Site, Bounded by Vesey, Church, Liberty Streets, & Route 9A, New York County, NY

  3. 11. Interior detail showing truss structure at shop area ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    11. Interior detail showing truss structure at shop area - Fort Hood, World War II Temporary Buildings, Company Maintenance Shop & Arms Room, North of Park Avenue at Forty-ninth Street, Killeen, Bell County, TX

  4. 35. MISCELLANEOUS ARCHITECTURAL AND STRUCTURAL DETAILS. INEEL DRAWING NUMBER 200063300287106359. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    35. MISCELLANEOUS ARCHITECTURAL AND STRUCTURAL DETAILS. INEEL DRAWING NUMBER 200-0633-00-287-106359. FLUOR NUMBER 5775-CPP-633-A-9. - Idaho National Engineering Laboratory, Old Waste Calcining Facility, Scoville, Butte County, ID

  5. Interior detail of third level structural elements at south end; ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Interior detail of third level structural elements at south end; camera facing west. - Mare Island Naval Shipyard, Supply Building, Walnut Avenue, southeast corner of Walnut Avenue & Fifth Street, Vallejo, Solano County, CA

  6. 8. Interior of Building 1015 (land plane hangar), structural detail, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    8. Interior of Building 1015 (land plane hangar), structural detail, looking northeast - Naval Air Station Chase Field, Building 1015, Byrd Street, .82 mile South-southeast of intersection of Texas State Highway 202 & Independence Street, Beeville, Bee County, TX

  7. 7. Interior of Building 1015 (land plane hangar), structural detail, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    7. Interior of Building 1015 (land plane hangar), structural detail, looking northeast - Naval Air Station Chase Field, Building 1015, Byrd Street, .82 mile South-southeast of intersection of Texas State Highway 202 & Independence Street, Beeville, Bee County, TX

  8. 21. DETAIL OF STRUCTURAL BAY ON NORTH ELEVATION OF BUILDING ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    21. DETAIL OF STRUCTURAL BAY ON NORTH ELEVATION OF BUILDING 216 (AMMUNITION MAINTENANCE SHOP) IN ASSEMBLY AREA. - Loring Air Force Base, Weapons Storage Area, Northeastern corner of base at northern end of Maine Road, Limestone, Aroostook County, ME

  9. 9. Detail of viaduct's structural system with cattle pens beneath. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    9. Detail of viaduct's structural system with cattle pens beneath. View to northeast. - South Omaha Union Stock Yards, Buckingham Road Viaduct, Twenty-ninth Street spanning Stockyard Cattle Pens, Omaha, Douglas County, NE

  10. Detail of the wharf support structure with four pipes running ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Detail of the wharf support structure with four pipes running across - U.S. Naval Base, Pearl Harbor, Marine Railway No. 2, Crane Wharf, Near intersection of Avenue G & Third Street , Pearl City, Honolulu County, HI

  11. 12. Exterior detail view of roof structure at eave, showing ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    12. Exterior detail view of roof structure at eave, showing exposed rafter tails, skip sheathing and gutter - American Railway Express Company Freight Building, 1060 Northeast Division Street, Bend, Deschutes County, OR

  12. 5. CAR DUMP, VIEW SHOWING STRUCTURAL DETAIL BELOW CONTROL HOUSE, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    5. CAR DUMP, VIEW SHOWING STRUCTURAL DETAIL BELOW CONTROL HOUSE, BARNEY CAR CAN BE SEEN IN BACKROUND - Pennsylvania Railroad, Canton Coal Pier, Clinton Street at Keith Avenue (Canton area), Baltimore, Independent City, MD

  13. 20. Detail of lantern roof structure, with revolving lens beneath. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    20. Detail of lantern roof structure, with revolving lens beneath. (Blurred due to apparatus motion.) - Block Island Southeast Light, Spring Street & Mohegan Trail at Mohegan Bluffs, New Shoreham, Washington County, RI

  14. 11. DETAIL VIEW OF DAM 87, SHOWING STOPLOG STRUCTURE (PARTIALLY ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    11. DETAIL VIEW OF DAM 87, SHOWING STOPLOG STRUCTURE (PARTIALLY HIDDEN BY MARSH GRASSES IN LOWER PART OF PHOTO) AT RIGHT (WEST) END OF SPILLWAY - Upper Souris National Wildlife Refuge, Dam 87, Souris River Basin, Foxholm, Surrey (England), ND

  15. 22. Detail taken from center of bridge showing upper structure ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    22. Detail taken from center of bridge showing upper structure and roadway, from northwest. - Brady Street Bridge, Spanning Monongahela River at South Twenty-second Street, Pittsburgh, Allegheny County, PA

  16. 32. DETAIL OF BRIDGE COUNTERWEIGHTS AND SUSPENSION STRUCTURE BETWEEN BRIDGE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    32. DETAIL OF BRIDGE COUNTERWEIGHTS AND SUSPENSION STRUCTURE BETWEEN BRIDGE NOS. 12 AND 13. LOOKING EAST-SOUTHEAST. - Greenville Yard, Transfer Bridge System, Port of New York/New Jersey, Upper New York Bay, Jersey City, Hudson County, NJ

  17. 30. DETAIL OF COLLAPSED BRIDGE NO. 14 SUSPENSION STRUCTURE. LOOKING ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    30. DETAIL OF COLLAPSED BRIDGE NO. 14 SUSPENSION STRUCTURE. LOOKING SOUTHWEST. - Greenville Yard, Transfer Bridge System, Port of New York/New Jersey, Upper New York Bay, Jersey City, Hudson County, NJ

  18. 32. LOWER CHORD / FLOOR STRUCTURE DETAIL OF THROUGH TRUSS. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    32. LOWER CHORD / FLOOR STRUCTURE DETAIL OF THROUGH TRUSS. VIEW TO NORTH. - Abraham Lincoln Memorial Bridge, Spanning Missouri River on Highway 30 between Nebraska & Iowa, Blair, Washington County, NE

  19. 31. LOWER CHORD / FLOOR STRUCTURE DETAIL OF THROUGH TRUSS. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    31. LOWER CHORD / FLOOR STRUCTURE DETAIL OF THROUGH TRUSS. VIEW TO NORTH. - Abraham Lincoln Memorial Bridge, Spanning Missouri River on Highway 30 between Nebraska & Iowa, Blair, Washington County, NE

  20. 43. Detail, subdeck, east bridge land span showing typical structural ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    43. Detail, sub-deck, east bridge land span showing typical structural connections and relationship to stone pier. - Broadway Bridge, Spanning Foundry Street, MBTA Yard, Fort Point Channel, & Lehigh Street, Boston, Suffolk County, MA

  1. 18. DETAIL VIEW SHOWING SAWTOOTH MONITOR ROOF AND TYPICAL STRUCTURAL ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    18. DETAIL VIEW SHOWING SAWTOOTH MONITOR ROOF AND TYPICAL STRUCTURAL CONFIGURATION OF TOP STORY, NORTH SECTION, THIRD FLOOR, LOOKING WEST INTO SOUTH SECTION - Massachusetts Mills, Cloth Room-Section 15, 95 Bridge Street, Lowell, Middlesex County, MA

  2. 143. North Carolina route 181 grade separation structure. Detail of ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    143. North Carolina route 181 grade separation structure. Detail of the arch stones. View is east-southeast. - Blue Ridge Parkway, Between Shenandoah National Park & Great Smoky Mountains, Asheville, Buncombe County, NC

  3. 4. DETAIL VIEW OF CROSS SECTION OF STRUCTURE, SHOWING EXTERIOR ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. DETAIL VIEW OF CROSS SECTION OF STRUCTURE, SHOWING EXTERIOR FACINGS LINED WITH RUBBLE BACKING AND EARTH INFILL, LOOKING EAST - Rock Wall, North side of Battle Creek Canyon, Shingletown, Shasta County, CA

  4. 2. DETAIL OF STRUCTURAL SYSTEM FOR CANTILEVERED HOG RUN; BUILDING ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. DETAIL OF STRUCTURAL SYSTEM FOR CANTILEVERED HOG RUN; BUILDING 168 (1960 HOG KILL) IS BENEATH HOG RUN - Rath Packing Company, Cantilevered Hog Run, Sycamore Street between Elm & Eighteenth Streets, Waterloo, Black Hawk County, IA

  5. Visitor center flight room, detail of twin structural piers at ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Visitor center flight room, detail of twin structural piers at northeast corner supporting flight room dome - Wright Brothers National Memorial Visitor Center, Highway 158, Kill Devil Hills, Dare County, NC

  6. 11. Detail, southeast corner, showing decorative elements of main structure, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    11. Detail, southeast corner, showing decorative elements of main structure, and window at the second story of the hose tower. - Independent Hose Company No. 3, Nineteenth & Belmont Streets, Bellaire, Belmont County, OH

  7. 16. DETAIL VIEW OF TYPICAL STRUCTURAL ELEMENTS; CROSSBAY 3 BETWEEN ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    16. DETAIL VIEW OF TYPICAL STRUCTURAL ELEMENTS; CROSSBAY 3 BETWEEN D & E BAYS; LOOKING WSW. (Ryan) - Watervliet Arsenal, Building No. 135, Gillespie Road, South of Parker Road, Watervliet, Albany County, NY

  8. 6. DETAIL OF DRIVE TRUCK ASSEMBLY. MOBILE SERVICE STRUCTURE SPANNING ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. DETAIL OF DRIVE TRUCK ASSEMBLY. MOBILE SERVICE STRUCTURE SPANNING LAUNCHER BUILDING WITH FLAME DUCT FAR RIGHT; VIEW TO NORTHWEST. - Cape Canaveral Air Station, Launch Complex 17, Facility 28416, East end of Lighthouse Road, Cape Canaveral, Brevard County, FL

  9. 15. Photocopy of Engineering Drawing, Structural Steel Details (from City ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    15. Photocopy of Engineering Drawing, Structural Steel Details (from City of Norton Shores) - William S. Antisdale Memorial State Reward Bridge, Spanning Mona Lake at Henry Street, Norton Shores, Muskegon County, MI

  10. 21. INTERIOR DETAIL OF 1887 STRUCTURAL FRAMING, BUILDING 1. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    21. INTERIOR DETAIL OF 1887 STRUCTURAL FRAMING, BUILDING 1. - New Orleans City Railroad Company, Canal Station, Square 365, bounded by Canal, North Dupre, Iberville, & North White Streets, New Orleans, Orleans Parish, LA

  11. 23. INTERIOR DETAIL OF STRUCTURAL FRAMING, BUILDING 2. New ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    23. INTERIOR DETAIL OF STRUCTURAL FRAMING, BUILDING 2. - New Orleans City Railroad Company, Canal Station, Square 365, bounded by Canal, North Dupre, Iberville, & North White Streets, New Orleans, Orleans Parish, LA

  12. 14. Detail, crack evidencing structural failure, northeast rear, view to ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    14. Detail, crack evidencing structural failure, northeast rear, view to southwest, 90mm lens. Note failure of sandstone lintel above window. - Benicia Arsenal, Powder Magazine No. 5, Junction of Interstate Highways 680 & 780, Benicia, Solano County, CA

  13. 15. Detail, cracks evidencing structural failure, northeast rear, view to ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    15. Detail, cracks evidencing structural failure, northeast rear, view to southwest, 90mm lens. - Benicia Arsenal, Powder Magazine No. 5, Junction of Interstate Highways 680 & 780, Benicia, Solano County, CA

  14. 18. DETAIL VIEW OF THE HIGH BAY STRUCTURAL SYSTEM AND ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    18. DETAIL VIEW OF THE HIGH BAY STRUCTURAL SYSTEM AND WINDOW ILLUMINATION AT THE SHRINK PIT AREA, S END OF B BAY; LOOKING SSE. (Ceronie) - Watervliet Arsenal, Building No. 135, Gillespie Road, South of Parker Road, Watervliet, Albany County, NY

  15. 6. DETAILED INTERIOR VIEW OF SOUTH SECTION, SHOWING ROOF STRUCTURAL ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. DETAILED INTERIOR VIEW OF SOUTH SECTION, SHOWING ROOF STRUCTURAL SYSTEM, LOOKING NORTH AND UP - Marvine Colliery, Oil House, West side Boulevard Avenue, between East Parker Street & Route 380, Scranton, Lackawanna County, PA

  16. 6. Detail of heavy timber structural system at ground floor ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. Detail of heavy timber structural system at ground floor level of Tender Frame Shop. - Central of Georgia Railway, Savannah Repair Shops & Terminal Facilities, Tender Frame Shop, Bounded by West Broad, Jones, West Boundary & Hull Streets, Savannah, Chatham County, GA

  17. INTERIOR VIEW, DETAIL OF BARREL ROOF STRUCTURE, FACING NORTHEAST. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    INTERIOR VIEW, DETAIL OF BARREL ROOF STRUCTURE, FACING NORTHEAST. - Southern Branch of the National Home for Disabled Volunteer Soldiers, Building 13, Harris Avenue at its intersection of Black Avenue and Woodfin Street, Hampton, Hampton, VA

  18. Detailed analysis of structure and particle trajectories in sheared suspensions

    NASA Astrophysics Data System (ADS)

    Morris, Jeffrey; Katyal, Bhavana

    1999-11-01

    The structure and particle dynamics of sheared suspensions of hard spheres over a range of shear strength to Brownain motion (Péclet number, Pe) have been studied by detailed analysis of extended sampling of Stokesian Dynamics simulations of simple shear. The emphasis is upon large Pe. The structure has been analyzed by decomposition of the pair distribution function, g(r), into spherical harmonics; the harmonics are a complete set for the decompositon. The results indicate a profound and very marked change in structure due to shearing. It is shown that as Pe increases, the structure is increasingly distorted from teh equilibrium spherical symmetry and the number of harmonics required to recompose the original data to within an arbitrary accuracy increases, and this variation depends upon particle fraction. We present information on the content of the dominant harmonics as a function of radial distance for a pair, and interpret the results in terms of preferred directions in the material. Dynamic particle trajectories at time scales long relative to that used for the Brownian step are analyzed in a novel fashion by simple differential geometric measures, such as root mean square path curvature and torsion. Preliminary results illustrate that the path variation from mean flow correlates with the particle stress.

  19. DETAIL VIEW OF THE STRUCTURE OF THE BASE OF THE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    DETAIL VIEW OF THE STRUCTURE OF THE BASE OF THE TEST STAND AND THE TAIL SECTION OF A REDSTONE (JUPITER) ROCKET. NOTE THE FLAME DEFLECTOR BEHIND THE STRUCTURE IN THE FOREGROUND. - Marshall Space Flight Center, Redstone Rocket (Missile) Test Stand, Dodd Road, Huntsville, Madison County, AL

  20. Battery Berry Observation Station, detail, frame structure meeting older masonry ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Battery Berry Observation Station, detail, frame structure meeting older masonry building on west side of structure; view east - Fort McKinley, Battery Berry Observation Station, North side of Wood Side Drive approximately 80 feet east of Spring Cove Lane, Great Diamond Island, Portland, Cumberland County, ME

  1. 12. DETAIL VIEW OF STRUCTURE, FROM BELOW. VIEW OF THE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    12. DETAIL VIEW OF STRUCTURE, FROM BELOW. VIEW OF THE PARKER-MAYBERRY BRIDGE AND PART OF THE STRUCTURE OF THE COLORADO STREET BRIDGE, SEEN FROM THE ARROYO SECO BELOW THE COLORADO STREET BRIDGE - Colorado Street Bridge, Spanning Arroyo Seco at Colorado Boulevard, Pasadena, Los Angeles County, CA

  2. Photograph of elevation and details of structure 841, used for ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photograph of elevation and details of structure 841, used for repair project, dated 1973. Drawing in collection of Caretaker Site Office, Philadelphia Naval Business Center. - Naval Base Philadelphia-Philadelphia Naval Shipyard, Structure No. 841, Delaware Avenue between East Fourth Street & Webster Avenue, League Island, Philadelphia, Philadelphia County, PA

  3. 10. DETAIL SHOWING THRUST MEASURING SYSTEM. Looking up from the ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    10. DETAIL SHOWING THRUST MEASURING SYSTEM. Looking up from the test stand deck to east. - Edwards Air Force Base, Air Force Rocket Propulsion Laboratory, Test Stand 1-A, Test Area 1-120, north end of Jupiter Boulevard, Boron, Kern County, CA

  4. An Alternative Measure of Solar Activity from Detailed Sunspot Datasets

    NASA Astrophysics Data System (ADS)

    Muraközy, J.; Baranyi, T.; Ludmány, A.

    2016-11-01

    The sunspot number is analyzed by using detailed sunspot data, including aspects of observability, sunspot sizes, and proper identification of sunspot groups as discrete entities of solar activity. The tests show that in addition to the subjective factors there are also objective causes of the ambiguities in the series of sunspot numbers. To introduce an alternative solar-activity measure, the physical meaning of the sunspot number has to be reconsidered. It contains two components whose numbers are governed by different physical mechanisms and this is one source of the ambiguity. This article suggests an activity index, which is the amount of emerged magnetic flux. The only long-term proxy measure is the detailed sunspot-area dataset with proper calibration to the magnetic flux. The Debrecen sunspot databases provide an appropriate source for the establishment of the suggested activity index.

  5. Section A, detail view at parking structure of heatblistered paint ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Section A, detail view at parking structure of heat-blistered paint on column J3/10. Level B2, looking west/southwest. (BH) - World Trade Center Site, Bounded by Vesey, Church, Liberty Streets, & Route 9A, New York County, NY

  6. 5. Interior Detail of Roof Structure and Trusses Note: Photographs ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    5. Interior Detail of Roof Structure and Trusses Note: Photographs Nos. CA-1543F-6 through CA-1543F-19 are photocopies of construction drawings (various dates). Originals located at Mare Island Naval Shipyard-Staff Civil Engineer's Office. - Mare Island Naval Shipyard, Chemical Cleaning Facility, North of Fourteenth Street, between California & Railroad Avenue, Vallejo, Solano County, CA

  7. 31. Detail of Southeast Light lens and roof structure of ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    31. Detail of Southeast Light lens and roof structure of light gallery, 1985. Taken day after Hurricane Gloria, courtesy of Gerald F. Abbott and Block Island Historical Society. - Block Island Southeast Light, Spring Street & Mohegan Trail at Mohegan Bluffs, New Shoreham, Washington County, RI

  8. 35. DETAIL VIEW OF THE UNDERSIDE AND SUPPORT STRUCTURE OF ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    35. DETAIL VIEW OF THE UNDERSIDE AND SUPPORT STRUCTURE OF THE ORE BINS. VIEW WAS TAKEN FROM THE STAIR LANDING BETWEEN THE BREAKER LEVEL AND THE STAMP LEVEL. - Standard Gold Mill, East of Bodie Creek, Northeast of Bodie, Bodie, Mono County, CA

  9. Interior detail of the north side roof structure and windows ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Interior detail of the north side roof structure and windows in the sail loft. View facing east northeast - U.S. Naval Base, Pearl Harbor, Shipfitter's Shop, Seventh Street near Avenue C, Adjacent to Repair Basins, Pearl City, Honolulu County, HI

  10. 10. Exterior view, showing the structural details and tanks above ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    10. Exterior view, showing the structural details and tanks above at walk-in entry level (bottom) of Test Cell 7, Systems Integration Laboratory Building (T-28), looking west. - Air Force Plant PJKS, Systems Integration Laboratory, Systems Integration Laboratory Building, Waterton Canyon Road & Colorado Highway 121, Lakewood, Jefferson County, CO

  11. 6. Exterior view, showing structural details and instrumentation at the ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. Exterior view, showing structural details and instrumentation at the walk-in entry level (bottom) of Test Cell 6, Systems Integration Laboratory Building (T-28), looking southwest. - Air Force Plant PJKS, Systems Integration Laboratory, Systems Integration Laboratory Building, Waterton Canyon Road & Colorado Highway 121, Lakewood, Jefferson County, CO

  12. 26. DETAIL OF STRUCTURAL COLLAPSE OF TOP FLOOR OF MILL, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    26. DETAIL OF STRUCTURAL COLLAPSE OF TOP FLOOR OF MILL, ABOVE ORE BIN, LOOKING WEST FROM TOP OF STAIRWAY IN CA-290-25. THE PIPE AT CENTER WAS USED TO SPREAD CRUSHED ORE COMING FROM THE JAW CRUSHER EVENLY TO ALL AREA OF THE ORE BIN BELOW. - Skidoo Mine, Park Route 38 (Skidoo Road), Death Valley Junction, Inyo County, CA

  13. 16. STRUCTURAL DETAILS: CHANNEL, BIT & CLEAT, ANCHOR BOLTS & ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    16. STRUCTURAL DETAILS: CHANNEL, BIT & CLEAT, ANCHOR BOLTS & PLATES FOR PIERS 4, 5, AND 6, DWG. NO. 97, 1-1/2" = 1', MADE BY A.F., JUNE 13, 1908 - Baltimore Inner Harbor, Pier 5, South of Pratt Street between Market Place & Concord Street, Baltimore, Independent City, MD

  14. Structure A, architectural sections & details. Drawing no. H2, revised ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Structure A, architectural sections & details. Drawing no. H2, revised as-built dated October 11, 1951. Original drawing by Black & Veatch, consulting engineers, Kansas City, Missouri, prepared for the U.S. Department of the Army, Office of Engineers, Military Construction Division, Washington, D.C. dated October 1. - Travis Air Force Base, Building No. 925, W Street, Fairfield, Solano County, CA

  15. 52. INTERIOR OF BRIDGE SUSPENSION STRUCTURE AND DETAIL OF LIFTING ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    52. INTERIOR OF BRIDGE SUSPENSION STRUCTURE AND DETAIL OF LIFTING SCREW MACHINERY ABOVE BRIDGE NOS. 12 AND 11. LOOKING NORTH. - Greenville Yard, Transfer Bridge System, Port of New York/New Jersey, Upper New York Bay, Jersey City, Hudson County, NJ

  16. 73. DETAIL OF 'A' FRAME STRUCTURE LOOKING NORTH SHOWING PROJECTILE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    73. DETAIL OF 'A' FRAME STRUCTURE LOOKING NORTH SHOWING PROJECTILE CAR, CAMERA TOWER, CANTILEVERED WALKWAYS AND ELECTRICAL GEAR, August 17, 1948. (Original photograph in possession of Dave Willis, San Diego, California.) - Variable Angle Launcher Complex, Variable Angle Launcher, CA State Highway 39 at Morris Reservior, Azusa, Los Angeles County, CA

  17. Detail Hframe structure about five and onefourth miles southwest of ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Detail H-frame structure about five and one-fourth miles southwest of Morony Dam and Powerhouse showing one modern non-ceramic insulator and two historic porcelain suspension insulators - Morony Hydroelectric Facility, Morony-to-Rainbow 100 kV Transmission Line, West bank of the Missouri River, Great Falls, Cascade County, MT

  18. Detail of insulator array at first line structure showing historic ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Detail of insulator array at first line structure showing historic porcelain suspension insulators in strings of eight, porcelain jumper support insulators in strings of six, arch rings and ball weights - Morony Hydroelectric Facility, Morony-to-Rainbow 100 kV Transmission Line, West bank of the Missouri River, Great Falls, Cascade County, MT

  19. 5. STANDPIPE STRUCTURE DETAIL SHOWING CONNECTIONS TO PENSTOCKS, RIVETED SECTIONAL ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    5. STANDPIPE STRUCTURE DETAIL SHOWING CONNECTIONS TO PENSTOCKS, RIVETED SECTIONAL CONSTRUCTION OF TWO OF THE THREE ORIGINAL STANDPIPES (PHOTO RIGHT), WELDED SECTIONAL CONSTRUCTION OF FOURTH STANDPIPE, AND MODERN VENTILATION VALVES ON FIFTH PENSTOCK AT PHOTO LEFT CENTER BETWEEN FOURTH STANDPIPE AND ORIGINAL TWO. VIEW TO NORTHEAST. - Big Creek Hydroelectric System, Powerhouse 3 Penstock Standpipes, Big Creek, Big Creek, Fresno County, CA

  20. Detail of array structural elements through axis of array, looking ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Detail of array structural elements through axis of array, looking north-northeast - Over-the-Horizon Backscatter Radar Network, Columbia Falls Radar Site Receive Sector Two Antenna Array, At the end of Shadagee Ridge Road, Columbia Falls, Washington County, ME

  1. 26. DETAIL TO NORTH OF BUS STRUCTURE. NEW POWERHOUSE SECOND ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    26. DETAIL TO NORTH OF BUS STRUCTURE. NEW POWERHOUSE SECOND FLOOR, WITH OIL CIRCUIT BREAKER UNITS (LEFT) AND TANK LIFTER (CENTER) - Trenton Falls Hydroelectric Station, Powerhouse & Substation, On west bank of West Canada Creek, along Trenton Falls Road, 1.25 miles north of New York Route 28, Trenton Falls, Oneida County, NY

  2. Detail interior view of northeast stay tower at parking structure ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Detail interior view of northeast stay tower at parking structure in Section A showing graffiti, looking south between levels B3 and B4. Graffiti reads "God bless our local 3 brothers who gave their lives on 9-11-01 and all the rest! Amen" (BH) - World Trade Center Site, Bounded by Vesey, Church, Liberty Streets, & Route 9A, New York County, NY

  3. Hangar no. 2 interior detail of roof structures and interior ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Hangar no. 2 interior detail of roof structures and interior work spaces. Note concrete piers and cross bracing. Seen at trusses no. 42, 43, & 44. - Marine Corps Air Station Tustin, Southern Lighter Than Air Ship Hangar, Near intersection of Windmill Road & Johnson Street, Tustin, Orange County, CA

  4. ELECTRON MICROSCOPY OF STRUCTURAL DETAIL IN FROZEN BIOLOGICAL SPECIMENS

    PubMed Central

    Steere, Russell L.

    1957-01-01

    A procedure is described whereby preshadowed replicas can be obtained from frozen biological specimens which have been cut and then etched by sublimation of the ice from their surfaces. Electron micrographs showing details of the internal structure of plant virus crystals are presented to demonstrate the values of the procedure. Crystals of purified tobacco ringspot virus and squash mosaic virus and some portions of turnip yellow mosaic virus crystals have been shown to exhibit hexagonal packing. Sections through in situ crystals of tobacco mosaic virus show the rods to be parallel within each layer and arranged in a square net as viewed end on. Individual rods in each layer of the latter measure 300 mµ in length and are somewhat tilted with respect to the rods of adjacent layers. This results in the formation of a herring-bone appearance when a crystal is cut perpendicular to its hexagonal face. It is suggested that the procedure outlined here might well serve to supplement other procedures for the preparation of many cytological specimens for electron microscopy. PMID:13416310

  5. 12. "TEST STAND; STRUCTURAL; DEFLECTOR PIT DETAILS, SHEET NO. 1." ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    12. "TEST STAND; STRUCTURAL; DEFLECTOR PIT DETAILS, SHEET NO. 1." Specifications No. ENG-04-353-55-72; Drawing No. 60-09-12; sheet 41 of 148; file no. 1320/92, Rev. A. Stamped: RECORD DRAWING - AS CONSTRUCTED. Below stamp: Contract no. 4338, no change. - Edwards Air Force Base, Air Force Rocket Propulsion Laboratory, Test Stand 1-A Terminal Room, Test Area 1-120, north end of Jupiter Boulevard, Boron, Kern County, CA

  6. 9. "TEST STAND; STRUCTURAL; CABLE TUNNEL, PLAN, SECTIONS, DETAILS." Specifications ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    9. "TEST STAND; STRUCTURAL; CABLE TUNNEL, PLAN, SECTIONS, DETAILS." Specifications No. OC1-55-72-(Rev.); Drawing No. 60-09-12; sheet 43 of 148; file no. AF 1320/94, Rev. A. Stamped: RECORD DRAWING - AS CONSTRUCTED. Below stamp: Contract no. 4338, no change. - Edwards Air Force Base, Air Force Rocket Propulsion Laboratory, Test Stand 1-A Terminal Room, Test Area 1-120, north end of Jupiter Boulevard, Boron, Kern County, CA

  7. Detail View looking at the protected structure and landing gear ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Detail View looking at the protected structure and landing gear housing in the void created by the removal of the Forward Reaction Control System Module from the forward section of the Orbiter Discovery. This view was taken from the service platform in the Orbiter Processing Facility at Kennedy Space Center. - Space Transportation System, Orbiter Discovery (OV-103), Lyndon B. Johnson Space Center, 2101 NASA Parkway, Houston, Harris County, TX

  8. DETAIL VIEW, STRUCTURAL TIMBER AND FLOOR JOISTS, SOUTH GARRET. THIS ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    DETAIL VIEW, STRUCTURAL TIMBER AND FLOOR JOISTS, SOUTH GARRET. THIS TIMBER IS ONE OF TWO EXTENDING OUT FROM THE HOUSE AND JOINED TO VERTICAL POSTS LOCATED WITHIN THE WOOD TUSCAN COLUMNS LOCATED AT THE PORTICO’S TWO OUTER CORNERS. THE TIMBERS AND THE VISIBLE FLOOR JOISTS WERE PART OF THE HOUSE’S INITIAL CA. 1770 CONSTRUCTION - The Woodlands, 4000 Woodlands Avenue, Philadelphia, Philadelphia County, PA

  9. Detail of pier structure and wood fenders of Facility No. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Detail of pier structure and wood fenders of Facility No. B-1, showing floats in foreground and bollards on pier, view facing east - U.S. Naval Base, Pearl Harbor, South Quay Wall & Repair Wharf, L-shaped portion of quay walls starting at east side of mouth of Dry Dock No. 1, continuing along ocean side of Sixth Street, adjacent to Pier B-2, Pearl City, Honolulu County, HI

  10. 9. DETAIL OF DIVERSION STRUCTURE WEST OF DERBY LAKE (SECTION ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    9. DETAIL OF DIVERSION STRUCTURE WEST OF DERBY LAKE (SECTION 2) SHOWING DIVERSION GATE TO LAKE LADORA. - Highline Canal, Sand Creek Lateral, Beginning at intersection of Peoria Street & Highline Canal in Arapahoe County (City of Aurora), Sand Creek lateral Extends 15 miles Northerly through Araphoe County, City & County of Denver, & Adams County to its end point, approximately 1/4 mile Southest of intersectioin of D Street & Ninth Avenue in Adams County (Rocky Mountain Arsenal, Commerce City Vicinity), Commerce City, Adams County, CO

  11. 5. "TEST STAND 13, CONCRETE STRUCTURAL SECTIONS AND DETAILS." Specifications ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    5. "TEST STAND 1-3, CONCRETE STRUCTURAL SECTIONS AND DETAILS." Specifications No. OC12-50-10; Drawing No. 60-09-06; no sheet number within title block. D.O. SERIES 1109/17, Rev. A. Stamped: AS BUILT; NO CHANGES. Date of Revision A: 11/1/50. - Edwards Air Force Base, Air Force Rocket Propulsion Laboratory, Test Stand 1-3, Test Area 1-115, northwest end of Saturn Boulevard, Boron, Kern County, CA

  12. Structural details, pathways, and energetics of unfolding apomyoglobin.

    PubMed

    Onufriev, Alexey; Case, David A; Bashford, Donald

    2003-01-17

    Protein folding is often difficult to characterize experimentally because of the transience of intermediate states, and the complexity of the protein-solvent system. Atomistic simulations, which could provide more detailed information, have had to employ highly simplified models or high temperatures, to cope with the long time scales of unfolding; direct simulation of folding is even more problematic. We report a fully atomistic simulation of the acid-induced unfolding of apomyoglobin in which the protonation of acidic side-chains to simulate low pH is sufficient to induce unfolding at room temperature with no added biasing forces or other unusual conditions; and the trajectory is validated by comparison to experimental characterization of intermediate states. Novel insights provided by their analysis include: characterization of a dry swollen globule state forming a barrier to initial unfolding or final folding; observation of cooperativity in secondary and tertiary structure formation and its explanation in terms of dielectric environments; and structural details of the intermediate and the completely unfolded states. These insights involve time scales and levels of structural detail that are presently beyond the range of experiment, but come within reach through the simulation methods described here. An implicit solvation model is used to analyze the energetics of protein folding at various pH and ionic strength values, and a reasonable estimate of folding free energy is obtained. Electrostatic interactions are found to disfavor folding.

  13. Predicting contrast detail performance from objective measurements in digital mammography

    NASA Astrophysics Data System (ADS)

    Young, Kenneth C.; Alsager, Abdulaziz; Dance, David R.; Oduko, Jennifer M.; Gundogdu, Ozcan; Spyrou, Nicholas M.

    2009-02-01

    European Guidelines for quality control in digital mammography specify minimum and achievable standards of image quality in terms of threshold contrast, based on readings of images of the CDMAM test object by human observers. However the methodology is time-consuming and has large inter- and intra-observer error. To overcome these problems a software program is available to automatically read CDMAM images. An alternative approach would be to predict threshold contrast from measurements of DQE and MTF using a model of the imaging process. A simple signal-matched noise-integration model has been used to predict the contrast detail response of five different types of commercial digital mammography system (Siemens Inspiration, GE Senographe DS, and three types of Konica Minolta computerised radiography system). Measurements were made of the MTF and DQE of each detector and the noise equivalent apertures calculated. For each system sets of 16 images of the CDMAM test object were acquired at a range of dose levels and contrast-detail plots obtained using human observers and automated reading. The theoretically and experimentally determined threshold contrasts were compared. An encouragingly good level of agreement was found between the experimental data and theoretical predictions.

  14. Detailed stress tensor measurements in a centrifugal compressor vaneless diffuser

    SciTech Connect

    Pinarbasi, A.; Johnson, M.W.

    1996-04-01

    Detailed flow measurements have been made in the vaneless diffuser of a large low-speed centrifugal compressor using hot-wire anemometry. The three time mean velocity components and full stress tensor distributions have been determined on eight measurement plans within the diffuser. High levels of Reynolds stress result in the rapid mixing out of the blade wake. Although high levels of turbulent kinetic energy are found in the passage wake, they are not associated with strong Reynolds stresses and hence the passage wake mixes out only slowly. Low-frequency meandering of the wake position is therefore likely to be responsible for the high kinetic energy levels. The anisotropic nature of the turbulence suggests that Reynolds stress turbulence models are required for CFD modeling of diffuser flows.

  15. DETAIL VIEW OF UPPER TRAM TERMINAL STRUCTURE, LOOKING NORTHEAST TOWARD ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    DETAIL VIEW OF UPPER TRAM TERMINAL STRUCTURE, LOOKING NORTHEAST TOWARD THE REAR OF THE STRUCTURE. THE WHEELS AT THE TOP OF THE TRAM BUCKETS RODE OFF THE STATIONARY CABLES ONTO THE TRACK SUPPORTED BY THE "C" IRONS SUSPENDED FROM THE TOP TIMBERS, CLEARLY SEEN AT THE TOP OF THE FRAME. THE ANCHOR POINTS FOR THE TWO STATIONARY CABLES ARE AT BOTTOM CENTER, JUST BELOW THE CABLE WHEEL. THE MAIN CABLE WHEEL IS IN THE DISTANCE AT CENTER LEFT. THE ORE CHUTES COMING FROM THE ORE BIN ARE AT LEFT CENTER EDGE. TRAM BUCKETS WERE CHARGED HERE. - Keane Wonder Mine, Park Route 4 (Daylight Pass Cutoff), Death Valley Junction, Inyo County, CA

  16. Aircraft wing structural detail design (wing, aileron, flaps, and subsystems)

    NASA Technical Reports Server (NTRS)

    Downs, Robert; Zable, Mike; Hughes, James; Heiser, Terry; Adrian, Kenneth

    1993-01-01

    The goal of this project was to design, in detail, the wing, flaps, and ailerons for a primary flight trainer. Integrated in this design are provisions for the fuel system, the electrical system, and the fuselage/cabin carry-through interface structure. This conceptual design displays the general arrangement of all major components in the wing structure, taking into consideration the requirements set forth by the appropriate sections of Federal Aviation Regulation Part 23 (FAR23) as well as those established in the statement of work.

  17. Structural details of the glycosyltransferase step of peptidoglycan assembly.

    PubMed

    Lovering, Andrew L; Gretes, Michael; Strynadka, Natalie C J

    2008-10-01

    The importance of peptidoglycan in forming the basis of the bacterial cell wall has led to many studies investigating its synthesis. The step of cross-linkage via transpeptidation, and its inhibition by penicillins, has been extremely well characterized yet knowledge of the preceding glycosyltransfer reaction remained elusive until recently. The structures of two glycosyltransferase enzymes, catalyzing membrane-based polymerization of the lipid II monomer unit, have presented a means of elucidating the molecular details of this highly desirable antibiotic target. Evidence acquired before the publication of the structures is related here to these new findings, with particular emphasis on the recognition of substrates and inhibitors.

  18. Detailed signal model of coherent wind measurement lidar

    NASA Astrophysics Data System (ADS)

    Ma, Yuechao; Li, Sining; Lu, Wei

    2016-11-01

    Lidar is short for light detection and ranging, which is a tool to help measuring some useful information of atmosphere. In the recent years, more and more attention was paid to the research of wind measurement by lidar. Because the accurate wind information can be used not only in weather report, but also the safety guarantee of the airplanes. In this paper, a more detailed signal model of wind measurement lidar is proposed. It includes the laser transmitting part which describes the broadening of the spectral, the laser attenuation in the atmosphere, the backscattering signal and the detected signal. A Voigt profile is used to describe the broadening of the transmitting laser spectral, which is the most common situation that is the convolution of different broadening line shapes. The laser attenuation includes scattering and absorption. We use a Rayleigh scattering model and partially-Correlated quadratic-Velocity-Dependent Hard-Collision (pCqSDHC) model to describe the molecule scattering and absorption. When calculate the particles scattering and absorption, the Gaussian particles model is used to describe the shape of particles. Because of the Doppler Effect occurred between the laser and atmosphere, the wind velocity can be calculated by the backscattering signal. Then, a two parameter Weibull distribution is used to describe the wind filed, so that we can use it to do the future work. After all the description, the signal model of coherent wind measurement lidar is decided. And some of the simulation is given by MATLAB. This signal model can describe the system more accurate and more detailed, so that the following work will be easier and more efficient.

  19. Detailed Uncertainty Analysis of the ZEM-3 Measurement System

    NASA Technical Reports Server (NTRS)

    Mackey, Jon; Sehirlioglu, Alp; Dynys, Fred

    2014-01-01

    The measurement of Seebeck coefficient and electrical resistivity are critical to the investigation of all thermoelectric systems. Therefore, it stands that the measurement uncertainty must be well understood to report ZT values which are accurate and trustworthy. A detailed uncertainty analysis of the ZEM-3 measurement system has been performed. The uncertainty analysis calculates error in the electrical resistivity measurement as a result of sample geometry tolerance, probe geometry tolerance, statistical error, and multi-meter uncertainty. The uncertainty on Seebeck coefficient includes probe wire correction factors, statistical error, multi-meter uncertainty, and most importantly the cold-finger effect. The cold-finger effect plagues all potentiometric (four-probe) Seebeck measurement systems, as heat parasitically transfers through thermocouple probes. The effect leads to an asymmetric over-estimation of the Seebeck coefficient. A thermal finite element analysis allows for quantification of the phenomenon, and provides an estimate on the uncertainty of the Seebeck coefficient. The thermoelectric power factor has been found to have an uncertainty of +9-14 at high temperature and 9 near room temperature.

  20. Detailed Evaluation of MODIS Fire Radiative Power Measurements

    NASA Technical Reports Server (NTRS)

    Ichoku, Charles

    2010-01-01

    Satellite remote sensing is providing us tremendous opportunities to measure the fire radiative energy (FRE) release rate or power (FRP) from open biomass burning, which affects many vegetated regions of the world on a seasonal basis. Knowledge of the biomass burning characteristics and emission source strengths of different (particulate and gaseous) smoke constituents is one of the principal ingredients upon which the assessment, modeling, and forecasting of their distribution and impacts depend. This knowledge can be gained through accurate measurement of FRP, which has been shown to have a direct relationship with the rates of biomass consumption and emissions of major smoke constituents. Over the last decade or so, FRP has been routinely measured from space by both the MODIS sensors aboard the polar orbiting Terra and Aqua satellites, and the SEVIRI sensor aboard the Meteosat Second Generation (MSG) geostationary satellite. During the last few years, FRP has been gaining recognition as an important parameter for facilitating the development of various scientific studies relating to the quantitative characterization of biomass burning and their emissions. Therefore, we are conducting a detailed analysis of the FRP products from MODIS to characterize the uncertainties associated with them, such as those due to the MODIS bow-tie effects and other factors, in order to establish their error budget for use in scientific research and applications. In this presentation, we will show preliminary results of the MODIS FRP data analysis, including comparisons with airborne measurements.

  1. Partially Assembled Nucleosome Structures at Atomic Detail.

    PubMed

    Rychkov, Georgy N; Ilatovskiy, Andrey V; Nazarov, Igor B; Shvetsov, Alexey V; Lebedev, Dmitry V; Konev, Alexander Y; Isaev-Ivanov, Vladimir V; Onufriev, Alexey V

    2017-02-07

    The evidence is now overwhelming that partially assembled nucleosome states (PANS) are as important as the canonical nucleosome structure for the understanding of how accessibility to genomic DNA is regulated in cells. We use a combination of molecular dynamics simulation and atomic force microscopy to deliver, in atomic detail, structural models of three key PANS: the hexasome (H2A·H2B)·(H3·H4)2, the tetrasome (H3·H4)2, and the disome (H3·H4). Despite fluctuations of the conformation of the free DNA in these structures, regions of protected DNA in close contact with the histone core remain stable, thus establishing the basis for the understanding of the role of PANS in DNA accessibility regulation. On average, the length of protected DNA in each structure is roughly 18 basepairs per histone protein. Atomistically detailed PANS are used to explain experimental observations; specifically, we discuss interpretation of atomic force microscopy, Förster resonance energy transfer, and small-angle x-ray scattering data obtained under conditions when PANS are expected to exist. Further, we suggest an alternative interpretation of a recent genome-wide study of DNA protection in active chromatin of fruit fly, leading to a conclusion that the three PANS are present in actively transcribing regions in a substantial amount. The presence of PANS may not only be a consequence, but also a prerequisite for fast transcription in vivo.

  2. 115. Stage Level floor structure. Detail of the ends of ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    115. Stage Level floor structure. Detail of the ends of three movable stage floor sections. An inclined steel angle track attached to the web of the floor beam allows the sections to roll under the fixed floor. The upper section of the inclined track is hinged so it can be moved upward by a cam mechanism to raise the end of the movable section level with the stage floor. A similar mechanism was used to open and close the floor sections for the star lifts (see sheet 4 of 9, note 6; sheet 8 of 9, details 5, 6A and 6B; sheet 6 of 9, notes 2A, 2B, and 3; and photo IL-1007-120). The pulley, and tongue extending out from the end of the movable section, were used to move the sections back and forth. - Auditorium Building, 430 South Michigan Avenue, Chicago, Cook County, IL

  3. DETAIL VIEW OF UPPER TRAM TERMINAL STRUCTURE, LOOKING SOUTH TOWARD ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    DETAIL VIEW OF UPPER TRAM TERMINAL STRUCTURE, LOOKING SOUTH TOWARD THE FRONT OF THE STRUCTURE. THE WHEELS AT THE TOP OF THE TRAM BUCKETS RODE OFF THE STATIONARY CABLES ONTO THE TRACK SUPPORTED BY THE "C" IRONS SUSPENDED FROM THE TOP TIMBERS ON THE LEFT AND RIGHT. THE BUCKET OPENING MECHANISM IS ON THE LEFT, AND PART OF THE CLOSING MECHANISM ON THE RIGHT EDGE OF THE FRAME. THE TWO CABLES AT CENTER ARE THE STATIONARY TRAM CABLES THAT RUN ALONG THE TOP OF THE SUPPORT TOWERS ON WHICH THE WHEELS OF THE TRAM BUCKETS RODE. THEY ARE ANCHORED AT GROUND LEVEL JUST OFF FRAME TO THE LOWER LEFT. - Keane Wonder Mine, Park Route 4 (Daylight Pass Cutoff), Death Valley Junction, Inyo County, CA

  4. Detailed electromagnetic simulation for the structural color of butterfly wings.

    PubMed

    Lee, R Todd; Smith, Glenn S

    2009-07-20

    Many species of butterflies exhibit interesting optical phenomena due to structural color. The physical reason for this color is subwavelength features on the surface of a single scale. The exposed surface of a scale is covered with a ridge structure. The fully three-dimensional, periodic, finite-difference time-domain method is used to create a detailed electromagnetic model of a generic ridge. A novel method for presenting the three-dimensional observed color pattern is developed. Using these tools, the change in color that is a result of varying individual features of the scale is explored. Computational models are developed that are similar to three butterflies: Morpho rhetenor, Troides magellanus, and Ancyluris meliboeus.

  5. Detailed temporal structure of communication networks in groups of songbirds.

    PubMed

    Stowell, Dan; Gill, Lisa; Clayton, David

    2016-06-01

    Animals in groups often exchange calls, in patterns whose temporal structure may be influenced by contextual factors such as physical location and the social network structure of the group. We introduce a model-based analysis for temporal patterns of animal call timing, originally developed for networks of firing neurons. This has advantages over cross-correlation analysis in that it can correctly handle common-cause confounds and provides a generative model of call patterns with explicit parameters for the influences between individuals. It also has advantages over standard Markovian analysis in that it incorporates detailed temporal interactions which affect timing as well as sequencing of calls. Further, a fitted model can be used to generate novel synthetic call sequences. We apply the method to calls recorded from groups of domesticated zebra finch (Taeniopygia guttata) individuals. We find that the communication network in these groups has stable structure that persists from one day to the next, and that 'kernels' reflecting the temporal range of influence have a characteristic structure for a calling individual's effect on itself, its partner and on others in the group. We further find characteristic patterns of influences by call type as well as by individual.

  6. Detailed temporal structure of communication networks in groups of songbirds

    PubMed Central

    Clayton, David

    2016-01-01

    Animals in groups often exchange calls, in patterns whose temporal structure may be influenced by contextual factors such as physical location and the social network structure of the group. We introduce a model-based analysis for temporal patterns of animal call timing, originally developed for networks of firing neurons. This has advantages over cross-correlation analysis in that it can correctly handle common-cause confounds and provides a generative model of call patterns with explicit parameters for the influences between individuals. It also has advantages over standard Markovian analysis in that it incorporates detailed temporal interactions which affect timing as well as sequencing of calls. Further, a fitted model can be used to generate novel synthetic call sequences. We apply the method to calls recorded from groups of domesticated zebra finch (Taeniopygia guttata) individuals. We find that the communication network in these groups has stable structure that persists from one day to the next, and that ‘kernels’ reflecting the temporal range of influence have a characteristic structure for a calling individual's effect on itself, its partner and on others in the group. We further find characteristic patterns of influences by call type as well as by individual. PMID:27335223

  7. The impact of model detail on power grid resilience measures

    NASA Astrophysics Data System (ADS)

    Auer, S.; Kleis, K.; Schultz, P.; Kurths, J.; Hellmann, F.

    2016-05-01

    Extreme events are a challenge to natural as well as man-made systems. For critical infrastructure like power grids, we need to understand their resilience against large disturbances. Recently, new measures of the resilience of dynamical systems have been developed in the complex system literature. Basin stability and survivability respectively assess the asymptotic and transient behavior of a system when subjected to arbitrary, localized but large perturbations in frequency and phase. To employ these methods that assess power grid resilience, we need to choose a certain model detail of the power grid. For the grid topology we considered the Scandinavian grid and an ensemble of power grids generated with a random growth model. So far the most popular model that has been studied is the classical swing equation model for the frequency response of generators and motors. In this paper we study a more sophisticated model of synchronous machines that also takes voltage dynamics into account, and compare it to the previously studied model. This model has been found to give an accurate picture of the long term evolution of synchronous machines in the engineering literature for post fault studies. We find evidence that some stable fix points of the swing equation become unstable when we add voltage dynamics. If this occurs the asymptotic behavior of the system can be dramatically altered, and basin stability estimates obtained with the swing equation can be dramatically wrong. We also find that the survivability does not change significantly when taking the voltage dynamics into account. Further, the limit cycle type asymptotic behaviour is strongly correlated with transient voltages that violate typical operational voltage bounds. Thus, transient voltage bounds are dominated by transient frequency bounds and play no large role for realistic parameters.

  8. Investigating structural details of lipid-cholesterol-A β interactions

    NASA Astrophysics Data System (ADS)

    Rai, Durgesh; Anunciado, Divina; Heller, William; O'Neill, Hugh; Urban, Volker; Qian, Shuo

    2015-03-01

    Alzheimer's disease (AD) is the most common form of dementia and is predicted to affect 1 in 85 people around the world by 2050. Amyloid beta (A β) -peptide, a peptide composed of 40- 42 amino acids that is the product of cleavage from the amyloid precursor protein (APP), is regarded to play a major role in the development of AD. In addition, accumulating evidence points to a positive association between cholesterol and AD. Here, we present results from our studies about A β-peptide and cholesterol in bilayer by small-angle neutron scattering (SANS) using a combination of dimyristoyl, phosphocholine (DMPC) and partially deuterated cholesterol (cholesterol-d7) with and without A β. We compare the results using grazing incidence and transmission SANS on lipid bilayer films and unilamellar vesicles respectively. The structural details on vesicles and bilayers work in conjunction with the circular dichroism on peptide in solution and oriented circular dichroism in bilayer films. The studies confirm a positive association of A β with the membrane layers. The results from different studies will be compared and contrasted in presentation.

  9. Detailed slab and mantle structure beneath westernmost Mediterranean

    NASA Astrophysics Data System (ADS)

    Sun, D.; Miller, M. S.; Bezada, M. J.; Humphreys, E.

    2013-12-01

    The geological evolution of the westernmost Mediterranean holds an important piece of the puzzle of how whole western Mediterranean evolved due to the convergence of Africa with Eurasia. Detailed upper mantle seismological images are crucial to test two controversial ideas about the dynamic process of the westernmost Mediterranean during the Cenozoic: slab rollback and lithosphere delamination. Recent tomographic images based on the dense seismic network in Spain and northern Morocco reveal a high-resolution continuous high-velocity anomaly to the transition zone depth under the Alboran domain [Bezada and Humphreys, 2013], which was used to support the slab roll back hypothesis for the westernmost Mediterranean tectonic evolution. However, the slab shape, width, and sharpness of its edges are not well resolved. Furthermore, the deep 2010 earthquake beneath Granada, Spain suggests possible oceanic crust material existing at ~ 600 km depth, which cannot be resolved by current tomography models. The study of multipathing and waveform broadening around sharp features has proven an efficient way to study those features. Here, we use both P and S waveform data from the PICASSO array to produce a detailed image. For the deep Granada earthquake, high frequency second arrivals and long coda after the P and S arrivals are shown on stations in the Rif Mountains of Morocco. By fitting both SH and P waveform data, we suggest that a low-velocity layer (LVL, 2 km thickness, δVs = -10%), possibly old oceanic crust, sits on top of the slab. The seismic waves travel through the LVL as guided waves preserving their high frequency energy. The strength of the second arrivals are very sensitive to the relative location between the deep earthquake and the LVL, which indicates the 2010 deep earthquake was most-likely within the subducted oceanic crust. Using both teleseismic and regional data, we conclude that the width of the sub-vertical slab is ~150 km, which is sharper than the

  10. An array for measuring detailed soil temperature profiles

    USDA-ARS?s Scientific Manuscript database

    Soil temperature dynamics can provide insights into soil variables which are much more difficult or impossible to measure. We designed an array to measure temperature at precise depth increments. Data was collected to determine if the construction materials influence surface and near-surface tempera...

  11. Scanners for analytic print measurement: the devil in the details

    NASA Astrophysics Data System (ADS)

    Zeise, Eric K.; Williams, Don; Burns, Peter D.; Kress, William C.

    2007-01-01

    Inexpensive and easy-to-use linear and area-array scanners have frequently substituted as colorimeters and densitometers for low-frequency (i.e., large area) hard copy image measurement. Increasingly, scanners are also being used for high spatial frequency, image microstructure measurements, which were previously reserved for high performance microdensitometers. In this paper we address characteristics of flatbed reflection scanners in the evaluation of print uniformity, geometric distortion, geometric repeatability and the influence of scanner MTF and noise on analytic measurements. Suggestions are made for the specification and evaluation of scanners to be used in print image quality standards that are being developed.

  12. Detailed Measurement of Horizontal Groundwater Velocities Without a Borehole

    NASA Astrophysics Data System (ADS)

    Bakker, M.; Calje, R.; Van der Made, K. J.; Schaars, F.

    2014-12-01

    A new methodology has been developed to measure horizontal groundwater velocities in unconsolidated aquifers. Groundwater velocities are measured with a heat tracer experiment. Temperature is measured along fiber optic cables using a Distributed Temperature Sensing (DTS) system. Fiber optic cables and a separate heating cable are pushed into the ground to depths of tens of meters. The groundwater is heated with the heating cable and the response is measured along several nearby fiber optic cables. The measured temperature responses are used to estimate the distribution of the magnitude and direction of the horizontal groundwater velocity over the entire depth of the cables. The methodology has been applied in a phreatic aquifer in the dune area along the Dutch coast. Significant variations of groundwater velocities with depth were observed even though the dune sand is relatively homogeneous. Major advantages of the new methodology are that the fiber optic cables are in direct contact with the groundwater and that the cables and installation are relatively cheap. No expensive boreholes are needed and consequently measurements are not affected by movement and mixing of water inside a borehole.

  13. Detailed requirements for a next generation nuclear data structure.

    SciTech Connect

    Brown, D.

    2016-07-05

    This document attempts to compile the requirements for the top-levels of a hierarchical arrangement of nuclear data such as found in the ENDF format. This set of requirements will be used to guide the development of a new data structure to replace the legacy ENDF format.

  14. Detailed analysis of the structural consequences of railgun augumentation

    SciTech Connect

    Wellman, G.W.; Schuler, K.W.

    1988-06-01

    The advantage of augmenting a plasma railgun is to provide the same driving force on the projectile as in an unaugmented railgun at a lower plasma arc current, thus producing less erosion and barrel damage. However, there are structural consequences to railgun augmentation which must be overcome before the advantages of lower plasma arc currents can be realized. To investigate these consequences, a bolted V-block supporting structure is considered with two cores; unaugmented (a single pair of conducting rails), and augmented (conducting rails augmented by a second tandem set of conductors). For each core, a two-dimensional dynamic finite element structural analysis is performed. The loadings, applied sequentially, consist of the static bolt preload, the plasma pressure behind the projectile, and the magnetic pressure induced by currents flowing in the rails or augmenting conductors. The magnetic pressure induced by currents flowing in the rails or augmenting conductors. A maximum rail current is found for which the unaugmented railgun can be fired without permanent deformation of the gun bore, thus allowing repeated firings. For the augmented railgun, at the same projectile acceleration, large permanent deformations are shown. 7 refs., 41 figs., 2 tabs.

  15. Detailed structure-function correlations of Bacillus subtilis acetolactate synthase.

    PubMed

    Sommer, Bettina; von Moeller, Holger; Haack, Martina; Qoura, Farah; Langner, Clemens; Bourenkov, Gleb; Garbe, Daniel; Loll, Bernhard; Brück, Thomas

    2015-01-02

    Isobutanol is deemed to be a next-generation biofuel and a renewable platform chemical.1 Non-natural biosynthetic pathways for isobutanol production have been implemented in cell-based and in vitro systems with Bacillus subtilis acetolactate synthase (AlsS) as key biocatalyst.2-6 AlsS catalyzes the condensation of two pyruvate molecules to acetolactate with thiamine diphosphate and Mg(2+) as cofactors. AlsS also catalyzes the conversion of 2-ketoisovalerate into isobutyraldehyde, the immediate precursor of isobutanol. Our phylogenetic analysis suggests that the ALS enzyme family forms a distinct subgroup of ThDP-dependent enzymes. To unravel catalytically relevant structure-function relationships, we solved the AlsS crystal structure at 2.3 Å in the presence of ThDP, Mg(2+) and in a transition state with a 2-lactyl moiety bound to ThDP. We supplemented our structural data by point mutations in the active site to identify catalytically important residues. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  16. Detailed Structural Characterization of Unbound Protein Phosphatase 1 Inhibitors

    PubMed Central

    Dancheck, Barbara; Nairn, Angus C.; Peti, Wolfgang

    2009-01-01

    Protein Phosphatase 1 (PP1) is an essential and ubiquitous serine/threonine protein phosphatase that is regulated by more than 100 known inhibitor and targeting proteins. It is currently unclear how protein inhibitors distinctly and specifically regulate PP1 to enable rapid responses to cellular alterations. We demonstrate that two PP1 inhibitors, I-2 and DARPP-32, belong to the class of intrinsically unstructured proteins (IUPs). We show that both inhibitors have distinct preferences for transient local and long range structure. These preferences are likely their structural signature for their interaction with PP1. Furthermore, we show that upon phosphorylation of Thr34 in DARPP-32, which turns DARPP-32 into a potent inhibitor of PP1, neither local nor long range structure of DARPP-32 is altered. Therefore, our data suggests a role for these transient 3-dimensional topologies in binding mechanisms that enable extensive contacts with PP1's invariant surfaces. Together, these interactions enable potent and selective inhibition of PP1. PMID:18954090

  17. Cutinisation of tomato fruit epidermis: Structural and morphological details

    PubMed Central

    Segado, Patricia; Domínguez, Eva; Heredia, Antonio

    2016-01-01

    ABSTRACT In tomato, the ovary is covered with a thin, electron-dense and uniform cuticle. The first 10 d after anthesis are critical in the cutinisation of the outer epidermal wall. During this period, singular cytoplasmic domains have been identified in the epidermal cells which seem to be involved in lipid biosynthesis. Moreover, the inner side of the procuticle showed a globular structure with vesicle-like particles of different size that seemed to migrate from the cytoplasm to the procuticle. These electron-dense particles are postulated to play an important role in early cutin synthesis. PMID:27031163

  18. Content, Structure, and Sequence of the Detailing Discipline at Kendall College of Art and Design.

    ERIC Educational Resources Information Center

    Mulder, Bruce E.

    A study identified the appropriate general content, structure, and sequence for a detailing discipline that promoted student achievement to professional levels. Its focus was the detailing discipline, a sequence of studio courses within the furniture design program at Kendall College of Art and Design, Grand Rapids, Michigan. (Detailing, an…

  19. Detailed tuning of structure and intramolecular communication are dispensable for processive motion of myosin VI.

    PubMed

    Elting, Mary Williard; Bryant, Zev; Liao, Jung-Chi; Spudich, James A

    2011-01-19

    Dimeric myosin VI moves processively hand-over-hand along actin filaments. We have characterized the mechanism of this processive motion by measuring the impact of structural and chemical perturbations on single-molecule processivity. Processivity is maintained despite major alterations in lever arm structure, including replacement of light chain binding regions and elimination of the medial tail. We present kinetic models that can explain the ATP concentration-dependent processivities of myosin VI constructs containing either native or artificial lever arms. We conclude that detailed tuning of structure and intramolecular communication are dispensable for processive motion, and further show theoretically that one proposed type of nucleotide gating can be detrimental rather than beneficial for myosin processivity. Copyright © 2011 Biophysical Society. Published by Elsevier Inc. All rights reserved.

  20. Structural power flow measurement

    SciTech Connect

    Falter, K.J.; Keltie, R.F.

    1988-12-01

    Previous investigations of structural power flow through beam-like structures resulted in some unexplained anomalies in the calculated data. In order to develop structural power flow measurement as a viable technique for machine tool design, the causes of these anomalies needed to be found. Once found, techniques for eliminating the errors could be developed. Error sources were found in the experimental apparatus itself as well as in the instrumentation. Although flexural waves are the carriers of power in the experimental apparatus, at some frequencies longitudinal waves were excited which were picked up by the accelerometers and altered power measurements. Errors were found in the phase and gain response of the sensors and amplifiers used for measurement. A transfer function correction technique was employed to compensate for these instrumentation errors.

  1. Detailed flow-field measurements over a 75 deg swept delta wing

    NASA Technical Reports Server (NTRS)

    Kjelgaard, Scott O.; Sellers, William L., III

    1990-01-01

    Results from an experimental investigation documenting the flowfield over a 75 deg swept delta wing at an angle-of-attack of 20.5 deg are presented. Results obtained include surface flow visualization, off-body flow visualization, and detailed flowfield surveys for various Reynolds numbers. Flowfield surveys at Reynolds numbers of 0.5, 1.0, and 1.5 million based on the root chord were conducted with both a Pitot pressure probe and a 5-hole pressure probe; and 3-component laser velocimeter surveys were conducted at a Reynolds number of 1.0 million. The Pitot pressure surveys were obtained at 5 chordwise stations, the 5-hole probe surveys were obtained at 3 chordwise stations and the laser velocimeter surveys were obtained at one station. The results confirm the classical roll up of the flow into a pair of primary vortices over the delta wing. The velocity measurements indicate that Reynolds number has little effect on the global structure of the flowfield for the Reynolds number range investigated. Measurements of the non-dimensional axial velocity in the core of the vortex indicate a jet like flow with values greater than twice freestream. Comparisons between velocity measurements from the 5-hole pressure probe and the laser velocimeter indicate that the pressure probe does a reasonable job of measuring the flowfield quantities where the velocity gradients in the flowfield are low.

  2. 36. ARCHITECTURAL AND STRUCTURAL DETAILS OF ELEVATOR HOUSING, NaK HEATER ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    36. ARCHITECTURAL AND STRUCTURAL DETAILS OF ELEVATOR HOUSING, NaK HEATER STACK ROOF FLASHING, HOOD ELEVATION DETAIL. INCLUDES PARTIAL 'BILL OF MATERIAL.' INEEL DRAWING NUMBER 200-0633-00-287-106361. FLUOR NUMBER 5775-CPP-633-A-11. - Idaho National Engineering Laboratory, Old Waste Calcining Facility, Scoville, Butte County, ID

  3. Creating Imaginative Worlds: Unique Details and Structure in Norma Fox Mazer's Young Adult Fiction.

    ERIC Educational Resources Information Center

    Angel, Ann

    2001-01-01

    Discusses how writer Norma Fox Mazer has helped many readers make the leap between reality and imagination simply in the way she handles details in the lives of her characters. Explores the ideas of communicating with detail, experimenting with structure, and playing with time in crucial scenes. (SG)

  4. Creating Imaginative Worlds: Unique Details and Structure in Norma Fox Mazer's Young Adult Fiction.

    ERIC Educational Resources Information Center

    Angel, Ann

    2001-01-01

    Discusses how writer Norma Fox Mazer has helped many readers make the leap between reality and imagination simply in the way she handles details in the lives of her characters. Explores the ideas of communicating with detail, experimenting with structure, and playing with time in crucial scenes. (SG)

  5. 22. U.S. Route 60 grade separation structure. Detail of the ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    22. U.S. Route 60 grade separation structure. Detail of the arch stones on the east elevation. View facing north. - Blue Ridge Parkway, Between Shenandoah National Park & Great Smoky Mountains, Asheville, Buncombe County, NC

  6. Detail of antenna tower structure, looking northnorthwest OvertheHorizon Backscatter ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Detail of antenna tower structure, looking north-northwest - Over-the-Horizon Backscatter Radar Network, Tulelake Radar Site Receive Sector Five Antenna Array, Unnamed Road West of Double Head Road, Tulelake, Siskiyou County, CA

  7. View south; interior structural detail at column A13 south bay ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    View south; interior structural detail at column A13 south bay - Naval Base Philadelphia-Philadelphia Naval Shipyard, Foundry-Propeller Shop, North of Porter Avenue, west of Third Street West, Philadelphia, Philadelphia County, PA

  8. View northeast; interior structural detail Naval Base PhiladelphiaPhiladelphia Naval ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    View northeast; interior structural detail - Naval Base Philadelphia-Philadelphia Naval Shipyard, Foundry-Propeller Shop, North of Porter Avenue, west of Third Street West, Philadelphia, Philadelphia County, PA

  9. A Unified Approach to Measurement Error and Missing Data: Details and Extensions

    ERIC Educational Resources Information Center

    Blackwell, Matthew; Honaker, James; King, Gary

    2017-01-01

    We extend a unified and easy-to-use approach to measurement error and missing data. In our companion article, Blackwell, Honaker, and King give an intuitive overview of the new technique, along with practical suggestions and empirical applications. Here, we offer more precise technical details, more sophisticated measurement error model…

  10. Mass Spectrometric Characterization of Protein Structure Details Refines the Proteome Signature for Invasive Ductal Breast Carcinoma

    NASA Astrophysics Data System (ADS)

    Röwer, Claudia; Koy, Cornelia; Hecker, Michael; Reimer, Toralf; Gerber, Bernd; Thiesen, Hans-Jürgen; Glocker, Michael O.

    2011-03-01

    Early diagnosis as well as individualized therapies are necessary to reduce the mortality of breast cancer, and personalized patient care strategies rely on novel prognostic or predictive factors. In this study, with six breast cancer patients, 2D gel analysis was applied for studying protein expression differences in order to distinguish invasive ductal breast carcinoma, the most frequent breast tumor subtype, from control samples. In total, 1203 protein spots were assembled in a 2D reference gel. Differentially abundant spots were subjected to peptide mass fingerprinting for protein identification. Twenty proteins with their corresponding 38 differentially expressed 2D gel spots were contained in our previously reported proteome signature, suggesting that distinct protein forms were contributing. In-depth MS/MS measurements enabled analyses of protein structure details of selected proteins. In protein spots that significantly contributed to our signature, we found that glyceraldehyde-3-phosphate dehydrogenase was N-terminally truncated, pyruvate kinase M2 and nucleoside diphosphate kinase A but not other isoforms of these proteins were of importance, and nucleophosmin phosphorylation at serine residues 106 and 125 were clearly identified. Principle component analysis and hierarchical clustering with normalized quantitative data from the 38 spots resulted in accurate separation of tumor from control samples. Thus, separation of tissue samples as in our initial proteome signature could be confirmed even with a different proteome analysis platform. In addition, detailed protein structure investigations enabled refining our proteome signature for invasive ductal breast carcinoma, opening the way to structure-/function studies with respect to disease processes and/or therapeutic intervention.

  11. Detailed heat flow measurements over the Juan de Fuca ridge system

    SciTech Connect

    Davis, E.E.; Lister, C.R.B.; Wade, U.S.; Hyndman, R.D.

    1980-01-10

    Eleven detailed profiles of heat flow measurements have been completed over young oceanic crust of the Juan de Fuca ridge system. Individual measurements were spaced typically 0.4--1 km apart along multiple-penetration lines from 3 to 20 km in total length, and each measurement was located with respect to structural and sedimentary features by simultaneous seismic reflection profiling. In all cases, the average heat flow is well below that predicted by simple conductivity cooled spreading models even when the sediment cover is thick and the nearest basement outcrop is 15 km away. This disparity is attributed to ventilated convective circulation of water in the crust. Large heat flow variability is common along all profiles. Variations are present at two scales. Small-scale variations (from 1 km to a few kilometers between significant heat flow maxima), present in the younger profiles, probably reflect the influence of local venting and permeability variations on permeable layer cellular convection. Large-scale variations (10--20 km between significant heat flow maxima), present in all profiles, may reflect the influence of regional circulation driven by cold water recharge at isolated basement outcrops. Laboratory experimental data indicate that normal celluar convection can coexist with larger-scale bilateral flows, so that there is no simple way to extract the permeable layer thickness from the surface heat flow data. There is a considerable reduction in the amplitude of small-scale heat flow variability over the range of crustal age studied (0.1x12.5 m.y.). This is probably caused by the thermal filtering effects of the sediment cover which increases from about 50 m near the ridge crests to over 700 m on the flanks.

  12. Simulating photon scattering effects in structurally detailed ventricular models using a Monte Carlo approach

    PubMed Central

    Bishop, Martin J.; Plank, Gernot

    2014-01-01

    Light scattering during optical imaging of electrical activation within the heart is known to significantly distort the optically-recorded action potential (AP) upstroke, as well as affecting the magnitude of the measured response of ventricular tissue to strong electric shocks. Modeling approaches based on the photon diffusion equation have recently been instrumental in quantifying and helping to understand the origin of the resulting distortion. However, they are unable to faithfully represent regions of non-scattering media, such as small cavities within the myocardium which are filled with perfusate during experiments. Stochastic Monte Carlo (MC) approaches allow simulation and tracking of individual photon “packets” as they propagate through tissue with differing scattering properties. Here, we present a novel application of the MC method of photon scattering simulation, applied for the first time to the simulation of cardiac optical mapping signals within unstructured, tetrahedral, finite element computational ventricular models. The method faithfully allows simulation of optical signals over highly-detailed, anatomically-complex MR-based models, including representations of fine-scale anatomy and intramural cavities. We show that optical action potential upstroke is prolonged close to large subepicardial vessels than further away from vessels, at times having a distinct “humped” morphology. Furthermore, we uncover a novel mechanism by which photon scattering effects around vessels cavities interact with “virtual-electrode” regions of strong de-/hyper-polarized tissue surrounding cavities during shocks, significantly reducing the apparent optically-measured epicardial polarization. We therefore demonstrate the importance of this novel optical mapping simulation approach along with highly anatomically-detailed models to fully investigate electrophysiological phenomena driven by fine-scale structural heterogeneity. PMID:25309442

  13. Simulating photon scattering effects in structurally detailed ventricular models using a Monte Carlo approach.

    PubMed

    Bishop, Martin J; Plank, Gernot

    2014-01-01

    Light scattering during optical imaging of electrical activation within the heart is known to significantly distort the optically-recorded action potential (AP) upstroke, as well as affecting the magnitude of the measured response of ventricular tissue to strong electric shocks. Modeling approaches based on the photon diffusion equation have recently been instrumental in quantifying and helping to understand the origin of the resulting distortion. However, they are unable to faithfully represent regions of non-scattering media, such as small cavities within the myocardium which are filled with perfusate during experiments. Stochastic Monte Carlo (MC) approaches allow simulation and tracking of individual photon "packets" as they propagate through tissue with differing scattering properties. Here, we present a novel application of the MC method of photon scattering simulation, applied for the first time to the simulation of cardiac optical mapping signals within unstructured, tetrahedral, finite element computational ventricular models. The method faithfully allows simulation of optical signals over highly-detailed, anatomically-complex MR-based models, including representations of fine-scale anatomy and intramural cavities. We show that optical action potential upstroke is prolonged close to large subepicardial vessels than further away from vessels, at times having a distinct "humped" morphology. Furthermore, we uncover a novel mechanism by which photon scattering effects around vessels cavities interact with "virtual-electrode" regions of strong de-/hyper-polarized tissue surrounding cavities during shocks, significantly reducing the apparent optically-measured epicardial polarization. We therefore demonstrate the importance of this novel optical mapping simulation approach along with highly anatomically-detailed models to fully investigate electrophysiological phenomena driven by fine-scale structural heterogeneity.

  14. Legacy tree data: A national database of detailed tree measurements for volume, weight, and physical properties

    Treesearch

    P.J. Radtke; D.M. Walker; A.R. Weiskittel; J. Frank; J.W. Coulston; J.A. Westfall

    2015-01-01

    Forest mensurationists in the United States have expended considerable effort over the past century making detailed observations of trees’ dimensions. In recent decades efforts have focused increasingly on weights and physical properties. Work is underway to compile original measurements from past volume, taper, and weight or biomass studies for North American tree...

  15. Validations of CFD against detailed velocity and pressure measurements in water turbine runner flow

    NASA Astrophysics Data System (ADS)

    Nilsson, H.; Davidson, L.

    2003-03-01

    This work compares CFD results with experimental results of the flow in two different kinds of water turbine runners. The runners studied are the GAMM Francis runner and the Hölleforsen Kaplan runner. The GAMM Francis runner was used as a test case in the 1989 GAMM Workshop on 3D Computation of Incompressible Internal Flows where the geometry and detailed best efficiency measurements were made available. In addition to the best efficiency measurements, four off-design operating condition measurements are used for the comparisons in this work. The Hölleforsen Kaplan runner was used at the 1999 Turbine 99 and 2001 Turbine 99 - II workshops on draft tube flow, where detailed measurements made after the runner were used as inlet boundary conditions for the draft tube computations. The measurements are used here to validate computations of the flow in the runner.The computations are made in a single runner blade passage where the inlet boundary conditions are obtained from an extrapolation of detailed measurements (GAMM) or from separate guide vane computations (Hölleforsen). The steady flow in a rotating co-ordinate system is computed. The effects of turbulence are modelled by a low-Reynolds number k- turbulence model, which removes some of the assumptions of the commonly used wall function approach and brings the computations one step further.

  16. Measuring state trait properties of detail processing and global integration ability in eating disorders.

    PubMed

    Harrison, Amy; Tchanturia, Kate; Treasure, Janet

    2011-09-01

    Women with eating disorders (EDs) are reported to have strengths in local or detailed information processing and difficulties with coherence or global processing/integration. This study aimed to replicate these findings and additionally explore a global integration task which has not previously been reported for an ED group, the Fragmented Pictures Task (FPT). Two hundred and twenty-two women (50 with anorexia nervosa (AN), 48 with bulimia nervosa (BN), 35 recovered from AN and 89 controls (HC)) completed the Rey-Osterrieth Complex Figure Task (RCFT) to measure global/local processing strategies, the Group Embedded Figures Task (GEFT) to measure local processing and the FPT to measure global integration. Superior detail processing skills (GEFT) and a tendency to utilise detail processing strategies (RCFT) were associated with having AN, BN and being in recovery from AN. Global integration difficulties (FPT) were only observed in acute AN, whereas participants in the BN and recovered group performed similarly to HCs. People currently ill with, and recovered from EDs are skilled at detail processing. The acute phase of AN is associated with difficulties in global integration. © 2011 Informa Healthcare

  17. AN ASSESSMENT OF SIMPLIFIED VS. DETAILED METHODOLOGIES FOR SSI ANALYSES OF DEEPLY EMBEDDED STRUCTURES.

    SciTech Connect

    XU,J.MILLER,C.HOFMAYER,C.GRAVES,H.

    2004-03-04

    Sponsored by the US Nuclear Regulatory Commission (NRC), Brookhaven National Laboratory (BNL) is carrying out a research program to develop a technical basis to support the safety evaluation of deeply embedded and/or buried (DEB) structures as proposed for advanced reactor designs. In this program, the methods and computer programs established for the assessment of soil-structure interaction (SSI) effects for the current generation of light water reactors are evaluated to determine their applicability and adequacy in capturing the seismic behavior of DEB structures. This paper presents an assessment of the simplified vs. detailed methodologies for seismic analyses of DEB structures. In this assessment, a lump-mass beam model is used for the simplified approach and a finite element representation is employed for the detailed method. A typical containment structure embedded in a soil profile representative of a typical nuclear power plant site was utilized, considering various embedment depths from shallow to full burial. BNL used the CARES program for the simplified model and the SASSI2000 program for the detailed analyses. The calculated response spectra at the key locations of the DEB structure are used for the performance assessment of the applied methods for different depths of burial. Included in the paper are: (1) the description of both the simplified and detailed models for the SSI analyses of the DEB structure, (2) the comparison of the analysis results for the different depths of burial between the two methods, and (3) the performance assessment of the analysis methodologies for SSI analyses of DEB structures. The resulting assessment from this study has indicated that simplified methods may be capable of capturing the seismic response for much deeper embedded structures than would be normally allowed by the standard practice.

  18. Section A, detail view at parking structure of column J4/12 ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Section A, detail view at parking structure of column J4/12 at level B2, looking southeast, showing smoke damage at drop panel. (BH) - World Trade Center Site, Bounded by Vesey, Church, Liberty Streets, & Route 9A, New York County, NY

  19. PLUG STORAGE BUILDING, TRA611. STRUCTURAL DETAILS. FACE PLATE. FOURTEEN OPENINGS ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    PLUG STORAGE BUILDING, TRA-611. STRUCTURAL DETAILS. FACE PLATE. FOURTEEN OPENINGS LABELED FOR PLUGS FROM SPECIFIC SIZE GROUPS IN THE MTR. BLAW-KNOX 3150-811-2, 1/1951. INL INDEX NO. 531-0611-00-098-100694, REV. 1. - Idaho National Engineering Laboratory, Test Reactor Area, Materials & Engineering Test Reactors, Scoville, Butte County, ID

  20. Structure A, reinforcing details. Drawing No. H2302, as built, Original ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Structure A, reinforcing details. Drawing No. H2-302, as built, Original drawing by Black & Veatch, Consulting Engineers, Kansas City, Missouri, prepared for the U.S. Department of the Army, Office of Engineers, Military Construction Division, Washington, D.C. dated October 1, 1951. - Travis Air Force Base, Building No. 925, W Street, Fairfield, Solano County, CA

  1. STRUCTURAL DETAILS AND SECTIONS OF MAIN PROCESSING BUILDING (CPP601). INL ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    STRUCTURAL DETAILS AND SECTIONS OF MAIN PROCESSING BUILDING (CPP-601). INL DRAWING NUMBER 200-0601-00-291-103079. ALTERNATE ID NUMBER 542-11-B-73. - Idaho National Engineering Laboratory, Idaho Chemical Processing Plant, Fuel Reprocessing Complex, Scoville, Butte County, ID

  2. Detail of insulator array at Hframe structure on RyantoRainbow Line ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Detail of insulator array at H-frame structure on Ryan-to-Rainbow Line 1 about three miles southwest of Ryan Dam. Array has one historic porcelain suspension insulator and two non-ceramic insulators - Ryan Hydroelectric Facility, Ryan-to-Rainbow 100 kV Transmission Line, West bank of Missouri River, northeast of Great Falls, Great Falls, Cascade County, MT

  3. Detail of insulator array at Hframe structure on RyantoRainbow Line ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Detail of insulator array at H-frame structure on Ryan-to-Rainbow Line 2 about three and one-fourth miles southwest of Ryan Dam. Array has three historic porcelain suspension insulators - Ryan Hydroelectric Facility, Ryan-to-Rainbow 100 kV Transmission Line, West bank of Missouri River, northeast of Great Falls, Great Falls, Cascade County, MT

  4. Detail of MoronytoRainbow Hframe structure just east of Ryan Dam ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Detail of Morony-to-Rainbow H-frame structure just east of Ryan Dam Road showing three historic porcelain suspension insulators in strings of six. View to east - Morony Hydroelectric Facility, Morony-to-Rainbow 100 kV Transmission Line, West bank of the Missouri River, Great Falls, Cascade County, MT

  5. 177. U.S. Route 70 grade separation structure. Detail of the ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    177. U.S. Route 70 grade separation structure. Detail of the stone facing. Notice it is thicker at the base than at the top. Facing north-northeast. - Blue Ridge Parkway, Between Shenandoah National Park & Great Smoky Mountains, Asheville, Buncombe County, NC

  6. A&M. Outside turntable, TAN705. Structural plan and details. Ralph M. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    A&M. Outside turntable, TAN-705. Structural plan and details. Ralph M. Parsons 902-3-ANP-705-S-149. Date: January 1953. Approved by INEEL index code no. 034-0705-60-693-106793 - Idaho National Engineering Laboratory, Test Area North, Scoville, Butte County, ID

  7. A&M. TAN607. Storage pool vestibule wall. Sections and structural details. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    A&M. TAN-607. Storage pool vestibule wall. Sections and structural details. Ralph M. Parsons 902-3-ANP-607-S137. Date: December 1952. INEEL index code no. 034-0607-62-693-106781 - Idaho National Engineering Laboratory, Test Area North, Scoville, Butte County, ID

  8. Hangar no. 2 structural detail. Tool room/GSE between trusses no. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Hangar no. 2 structural detail. Tool room/GSE between trusses no. 38 an no. 39. South side of room seen from window. Note footing for concrete piers and cross bracing. Looking 180 S. - Marine Corps Air Station Tustin, Southern Lighter Than Air Ship Hangar, Near intersection of Windmill Road & Johnson Street, Tustin, Orange County, CA

  9. Hangar no. 2 structural detail. Tool room/GSE between trusses no. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Hangar no. 2 structural detail. Tool room/GSE between trusses no. 38 an no. 39. North side of room seen from door. Note footing for concrete piers and cross bracing. Looking 2 N. - Marine Corps Air Station Tustin, Southern Lighter Than Air Ship Hangar, Near intersection of Windmill Road & Johnson Street, Tustin, Orange County, CA

  10. Detailed Studies on the Structure and Dynamics of Reacting Dusty Flows at Normal and Microgravity

    NASA Technical Reports Server (NTRS)

    Andac, M. Gurhan; Cracchiola, Brad; Egolfopoulos, Fokion N.; Campbell, Charles S.

    1999-01-01

    Dusty reacting flows are of particular interest for a wide range of applications. Inert particles can alter the flammability and extinction limits of a combustible mixture. Reacting particles can release substantial amount of heat and can be used either for power generation or propulsion. Accumulation of combustible particles in air can result in explosions which, for example, can occur in grain elevators, during lumber milling and in mine galleries. Furthermore, inert particles are used as flow velocity markers in reacting flows, and their velocity is measured by non-intrusive laser diagnostic techniques. Despite their importance, dusty reacting flows have been less studied and understood compared to gas phase as well as sprays. The addition of solid particles in a flowing gas stream can lead to strong couplings between the two phases, which can be of dynamic, thermal, and chemical nature. The dynamic coupling between the two phases is caused by the inertia that causes the phases to move with different velocities. Furthermore, gravitational, thermophoretic, photophoretic, electrophoretic, diffusiophoretic, centrifugal, and magnetic forces can be exerted on the particles. In general, magnetic, electrophoretic, centrifugal, photophoretic, and diffusiophoretic can be neglected. On the other hand, thermophoretic forces, caused by steep temperature gradients, can be important. The gravitational forces are almost always present and can affect the dynamic response of large particles. Understanding and quantifying the chemical coupling between two phases is a challenging task. However, all reacting particles begin this process as inert particles, and they must be heated before they participate in the combustion process. Thus, one must first understand the interactions of inert particles in a combustion environment. The in-detail understanding of the dynamics and structure of dusty flows can be only advanced by considering simple flow geometries such as the opposed

  11. Detailed Studies on the Structure and Dynamics of Reacting Dusty Flows at Normal and Microgravity

    NASA Technical Reports Server (NTRS)

    Andac, M. Gurhan; Cracchiola, Brad; Egolfopoulos, Fokion N.; Campbell, Charles S.

    1999-01-01

    Dusty reacting flows are of particular interest for a wide range of applications. Inert particles can alter the flammability and extinction limits of a combustible mixture. Reacting particles can release substantial amount of heat and can be used either for power generation or propulsion. Accumulation of combustible particles in air can result in explosions which, for example, can occur in grain elevators, during lumber milling and in mine galleries. Furthermore, inert particles are used as flow velocity markers in reacting flows, and their velocity is measured by non-intrusive laser diagnostic techniques. Despite their importance, dusty reacting flows have been less studied and understood compared to gas phase as well as sprays. The addition of solid particles in a flowing gas stream can lead to strong couplings between the two phases, which can be of dynamic, thermal, and chemical nature. The dynamic coupling between the two phases is caused by the inertia that causes the phases to move with different velocities. Furthermore, gravitational, thermophoretic, photophoretic, electrophoretic, diffusiophoretic, centrifugal, and magnetic forces can be exerted on the particles. In general, magnetic, electrophoretic, centrifugal, photophoretic, and diffusiophoretic can be neglected. On the other hand, thermophoretic forces, caused by steep temperature gradients, can be important. The gravitational forces are almost always present and can affect the dynamic response of large particles. Understanding and quantifying the chemical coupling between two phases is a challenging task. However, all reacting particles begin this process as inert particles, and they must be heated before they participate in the combustion process. Thus, one must first understand the interactions of inert particles in a combustion environment. The in-detail understanding of the dynamics and structure of dusty flows can be only advanced by considering simple flow geometries such as the opposed

  12. Detailed high-accuracy megavoltage transmission measurements: A sensitive experimental benchmark of EGSnrc

    SciTech Connect

    Ali, E. S. M.; McEwen, M. R.; Rogers, D. W. O.

    2012-10-15

    Purpose: There are three goals for this study: (a) to perform detailed megavoltage transmission measurements in order to identify the factors that affect the measurement accuracy, (b) to use the measured data as a benchmark for the EGSnrc system in order to identify the computational limiting factors, and (c) to provide data for others to benchmark Monte Carlo codes. Methods: Transmission measurements are performed at the National Research Council Canada on a research linac whose incident electron parameters are independently known. Automated transmission measurements are made on-axis, down to a transmission value of {approx}1.7%, for eight beams between 10 MV (the lowest stable MV beam on the linac) and 30 MV, using fully stopping Be, Al, and Pb bremsstrahlung targets and no fattening filters. To diversify energy differentiation, data are acquired for each beam using low-Z and high-Z attenuators (C and Pb) and Farmer chambers with low-Z and high-Z buildup caps. Experimental corrections are applied for beam drifts (2%), polarity (2.5% typical maximum, 6% extreme), ion recombination (0.2%), leakage (0.3%), and room scatter (0.8%)-the values in parentheses are the largest corrections applied. The experimental setup and the detectors are modeled using EGSnrc, with the newly added photonuclear attenuation included (up to a 5.6% effect). A detailed sensitivity analysis is carried out for the measured and calculated transmission data. Results: The developed experimental protocol allows for transmission measurements with 0.4% uncertainty on the smallest signals. Suggestions for accurate transmission measurements are provided. Measurements and EGSnrc calculations agree typically within 0.2% for the sensitivity of the transmission values to the detector details, to the bremsstrahlung target material, and to the incident electron energy. Direct comparison of the measured and calculated transmission data shows agreement better than 2% for C (3.4% for the 10 MV beam) and

  13. Detailed high-accuracy megavoltage transmission measurements: a sensitive experimental benchmark of EGSnrc.

    PubMed

    Ali, E S M; McEwen, M R; Rogers, D W O

    2012-10-01

    There are three goals for this study: (a) to perform detailed megavoltage transmission measurements in order to identify the factors that affect the measurement accuracy, (b) to use the measured data as a benchmark for the EGSnrc system in order to identify the computational limiting factors, and (c) to provide data for others to benchmark Monte Carlo codes. Transmission measurements are performed at the National Research Council Canada on a research linac whose incident electron parameters are independently known. Automated transmission measurements are made on-axis, down to a transmission value of ∼1.7%, for eight beams between 10 MV (the lowest stable MV beam on the linac) and 30 MV, using fully stopping Be, Al, and Pb bremsstrahlung targets and no fattening filters. To diversify energy differentiation, data are acquired for each beam using low-Z and high-Z attenuators (C and Pb) and Farmer chambers with low-Z and high-Z buildup caps. Experimental corrections are applied for beam drifts (2%), polarity (2.5% typical maximum, 6% extreme), ion recombination (0.2%), leakage (0.3%), and room scatter (0.8%)-the values in parentheses are the largest corrections applied. The experimental setup and the detectors are modeled using EGSnrc, with the newly added photonuclear attenuation included (up to a 5.6% effect). A detailed sensitivity analysis is carried out for the measured and calculated transmission data. The developed experimental protocol allows for transmission measurements with 0.4% uncertainty on the smallest signals. Suggestions for accurate transmission measurements are provided. Measurements and EGSnrc calculations agree typically within 0.2% for the sensitivity of the transmission values to the detector details, to the bremsstrahlung target material, and to the incident electron energy. Direct comparison of the measured and calculated transmission data shows agreement better than 2% for C (3.4% for the 10 MV beam) and typically better than 1% for Pb. The

  14. Optical grating evaluator - A device for detailed measurement of diffraction grating efficiencies in the vacuum ultraviolet

    NASA Technical Reports Server (NTRS)

    Michels, D. J.; Hunter, W. R.; Mikes, T. L.

    1974-01-01

    A device for detailed measurement of diffraction grating efficiencies and over-all performance in the VUV has been designed and constructed at the Naval Research Laboratory. The system employs semiautomated mechanisms to scan the face of the grating with a narrow monochromatic beam, and an efficiency map of the grating surface is produced on a strip chart recorder. Grating efficiency in the various diffracted orders and intensity of light scattered between orders may also be measured. A unique feature is the ability to determine the angle and effectiveness of grating blaze and variations in blaze under different conditions of illumination.

  15. PROCESS WATER BUILDING, TRA605. BASEMENT FLOOR PLAN AND STRUCTURAL DETAILS. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    PROCESS WATER BUILDING, TRA-605. BASEMENT FLOOR PLAN AND STRUCTURAL DETAILS. SUMP TANK (DIAMETER 33 FEET; CAPACITY 100,000 GALLONS) LOCATION IN HIGH ROOF SECTION ON WEST SIDE. REPAIR SHOP AND STORAGE AREA IN LOW-ROOF AREA. WALL DETAILS: THICKNESS OF REINFORCED CONCRETE RANGES FROM 1'-6" TO 2' THICK. FOUNDATIONS FOR FIVE CELLS ENCLOSING PUMPS. BLAW-KNOX 3150-805-2, 12/1950. INL INDEX NO. 531-0605-62-098-100658, REV. 3. - Idaho National Engineering Laboratory, Test Reactor Area, Materials & Engineering Test Reactors, Scoville, Butte County, ID

  16. Improving wildlife habitat model performance: Sensitivity to the scale and detail of vegetation measurements

    NASA Astrophysics Data System (ADS)

    Roberts, Lance Jay, Jr.

    Monitoring the impacts of resource use and landscape change on wildlife habitat over large areas is a daunting assignment. Forest land managers could benefit from linking the frequent decisions of resource use (timber harvesting) with a system of wildlife habitat accounting, but to date these tools are not widely available. I examined aspects of wildlife habitat modeling that: (in Chapter 2) could potentially lead to the establishment of wildlife habitat accounting within a resource decision support tool, (in Chapter 3) improve our theoretical understanding and methods to interpret the accuracy of wildlife habitat models, (in Chapter 4) explore the effects of vegetation classification systems on wildlife habitat model results, and (in Chapter 5) show that forest structural estimates from satellite imagery can improve potential habitat distribution models (GAP) for forest bird species. The majority of the analyses in this dissertation were done using a forest resource inventory developed by the State of Michigan (IFMAP). Paired with field vegetation and bird samples from sites across the lower peninsula of Michigan, we compared the relative accuracy of wildlife habitat relationship models built with plot-scale vegetation samples and stand-scale forest inventory maps. Recursive partitioning trees were used to build wildlife habitat models for 30 bird species. The habitat distribution maps from the Michigan Gap Analysis (MIGAP) were used as a baseline for comparison of model accuracy results. Both the plot and stand-scale measurements achieved high accuracy and there were few large differences between plot and stand-scale models for any individual species. Where the plot and stand-scale models were different, they tended to be species associated with mixed habitats. This may be evidence that scale of vegetation measurement has a larger influence on species associated with edges and ecotones. Habitat models that were built solely with land cover data were less accurate

  17. Detailed requirements document for the integrated structural analysis system, phase B

    NASA Technical Reports Server (NTRS)

    Rainey, J. A.

    1976-01-01

    The requirements are defined for a software system entitled integrated Structural Analysis System (ISAS) Phase B which is being developed to provide the user with a tool by which a complete and detailed analysis of a complex structural system can be performed. This software system will allow for automated interface with numerous structural analysis batch programs and for user interaction in the creation, selection, and validation of data. This system will include modifications to the 4 functions developed for ISAS, and the development of 25 new functions. The new functions are described.

  18. Detailed measurements in the SSME high pressure fuel turbine with smooth rotor blades

    NASA Technical Reports Server (NTRS)

    Hudson, Susan T.

    1993-01-01

    Several tests of the Rocketdyne configuration of the Space Shuttle Main Engine (SSME) High Pressure Fuel Turbopump (HPFTP) Turbine have been completed in the Turbine Test Equipment (TTE) at Marshall Space Flight Center. The tests involved using scaled performance parameters and model measurements to predict the performance of the turbine. The overall performance has been the primary objective of the tests to date, but more detailed measurements are also of interest. During the most recent test of the Rocketdyne configuration of the HPFTP turbine with smooth rotor blades, several different measurement techniques were used to study the turbine inlet and exit velocity profiles, boundary layer thicknesses, turbulence intensities, etc. Data has been obtained using various hot film probes and three-hole cobra probes. Laser Velocimeter measurements were also made. The test plan and test data will be presented and discussed as well as lessons learned on how to obtain the various types of data.

  19. Detailed measurements in the SSME high pressure fuel turbine with smooth rotor blades

    NASA Astrophysics Data System (ADS)

    Hudson, Susan T.

    1993-07-01

    Several tests of the Rocketdyne configuration of the Space Shuttle Main Engine (SSME) High Pressure Fuel Turbopump (HPFTP) Turbine have been completed in the Turbine Test Equipment (TTE) at Marshall Space Flight Center. The tests involved using scaled performance parameters and model measurements to predict the performance of the turbine. The overall performance has been the primary objective of the tests to date, but more detailed measurements are also of interest. During the most recent test of the Rocketdyne configuration of the HPFTP turbine with smooth rotor blades, several different measurement techniques were used to study the turbine inlet and exit velocity profiles, boundary layer thicknesses, turbulence intensities, etc. Data has been obtained using various hot film probes and three-hole cobra probes. Laser Velocimeter measurements were also made. The test plan and test data will be presented and discussed as well as lessons learned on how to obtain the various types of data.

  20. Detailed Characteristics of Radiation Belt Electrons Revealed by CSSWE/REPTile Measurements

    NASA Astrophysics Data System (ADS)

    Zhang, K.; Li, X.; Schiller, Q.; Gerhardt, D. T.; Millan, R. M.

    2016-12-01

    The outer radiation belt electrons are highly dynamic. We study the detailed characteristics of the relativistic electrons in the outer belt using measurements from the Colorado Student Space Weather Experiment (CSSWE) mission, a low Earth orbit Cubesat, which transverses the radiation belt four times in one orbit ( 1.5 hr) and has the advantage of measuring the dynamic activities of the electrons including their rapid precipitations. Among the features of the relativistic electrons, we show the measured electron distribution as a function of geomagnetic activities and local magnetic field strength. Moreover, a specific precipitation band, which happened on 19 Jan 2013, is investigated based on the conjunctive measurement of CSSWE and the Balloon Array for Radiation belt Relativistic Electron Losses (BARREL). In this precipitation band event, the net loss of the 0.58 1.63 MeV electrons (L=3.5 6) is estimated to account for 6.84% of the total electron content.

  1. Processing of Uav Based Range Imaging Data to Generate Detailed Elevation Models of Complex Natural Structures

    NASA Astrophysics Data System (ADS)

    Kohoutek, T. K.; Eisenbeiss, H.

    2012-07-01

    Unmanned Aerial Vehicles (UAVs) are more and more used in civil areas like geomatics. Autonomous navigated platforms have a great flexibility in flying and manoeuvring in complex environments to collect remote sensing data. In contrast to standard technologies such as aerial manned platforms (airplanes and helicopters) UAVs are able to fly closer to the object and in small-scale areas of high-risk situations such as landslides, volcano and earthquake areas and floodplains. Thus, UAVs are sometimes the only practical alternative in areas where access is difficult and where no manned aircraft is available or even no flight permission is given. Furthermore, compared to terrestrial platforms, UAVs are not limited to specific view directions and could overcome occlusions from trees, houses and terrain structures. Equipped with image sensors and/or laser scanners they are able to provide elevation models, rectified images, textured 3D-models and maps. In this paper we will describe a UAV platform, which can carry a range imaging (RIM) camera including power supply and data storage for the detailed mapping and monitoring of complex structures, such as alpine riverbed areas. The UAV platform NEO from Swiss UAV was equipped with the RIM camera CamCube 2.0 by PMD Technologies GmbH to capture the surface structures. Its navigation system includes an autopilot. To validate the UAV-trajectory a 360° prism was installed and tracked by a total station. Within the paper a workflow for the processing of UAV-RIM data is proposed, which is based on the processing of differential GNSS data in combination with the acquired range images. Subsequently, the obtained results for the trajectory are compared and verified with a track of a UAV (Falcon 8, Ascending Technologies) carried out with a total station simultaneously to the GNSS data acquisition. The results showed that the UAV's position using differential GNSS could be determined in the centimetre to the decimetre level. The RIM

  2. Detailed noise measurements on the SR-7A propeller: Tone behavior with helical tip Mach number

    NASA Astrophysics Data System (ADS)

    Dittmar, James H.; Hall, David G.

    1991-12-01

    Detailed noise measurements were taken on the SR-7A propeller to investigate the behavior of the noise with helical tip Mach number and then to level off as Mach number was increased further. This behavior was further investigated by obtaining detailed pressure-time histories of data. The pressure-time histories indicate that a portion of the primary pressure pulse is progressively cancelled by a secondary pulse which results in the noise leveling off as the helical tip Mach number is increased. This second pulse appears to originate on the same blade as the primary pulse and is in some way connected to the blade itself. This leaves open the possibility of redesigning the blade to improve the cancellation; thereby, the propeller noise is reduced.

  3. Detailed noise measurements on the SR-7A propeller: Tone behavior with helical tip Mach number

    NASA Technical Reports Server (NTRS)

    Dittmar, James H.; Hall, David G.

    1991-01-01

    Detailed noise measurements were taken on the SR-7A propeller to investigate the behavior of the noise with helical tip Mach number and then to level off as Mach number was increased further. This behavior was further investigated by obtaining detailed pressure-time histories of data. The pressure-time histories indicate that a portion of the primary pressure pulse is progressively cancelled by a secondary pulse which results in the noise leveling off as the helical tip Mach number is increased. This second pulse appears to originate on the same blade as the primary pulse and is in some way connected to the blade itself. This leaves open the possibility of redesigning the blade to improve the cancellation; thereby, the propeller noise is reduced.

  4. Psychophysiological and behavioral measures for detecting concealed information: the role of memory for crime details.

    PubMed

    Nahari, Galit; Ben-Shakhar, Gershon

    2011-06-01

    This study examined the role of memory for crime details in detecting concealed information using the electrodermal measure, Symptom Validity Test, and Number Guessing Test. Participants were randomly assigned to three groups: guilty, who committed a mock theft; informed-innocents, who were exposed to crime-relevant items; and uninformed-innocents, who had no crime-relevant information. Participants were tested immediately or 1 week later. Results showed (a) all tests detected the guilty in the immediate condition, and combining the tests improved detection efficiency; (b) tests' efficiency declined in the delayed condition, mainly for peripheral details; (c) no distinction between guilty and informed innocents was possible in the immediate, yet some distinction emerged in the delayed condition. These findings suggest that, while time delay may somewhat reduce the ability to detect the guilty, it also diminishes the danger of accusing informed-innocents. Copyright © 2010 Society for Psychophysiological Research.

  5. EM-Fold: De novo atomic-detail protein structure determination from medium resolution density maps

    PubMed Central

    Lindert, Steffen; Alexander, Nathan; Wötzel, Nils; Karakaş, Mert; Stewart, Phoebe L.; Meiler, Jens

    2012-01-01

    Electron density maps of membrane proteins or large macromolecular complexes are frequently only determined at medium resolution between 4 Å and 10 Å, either by cryo-electron microscopy (cryoEM) or X-ray crystallography. In these density maps the general arrangement of secondary structure elements is revealed while their directionality and connectivity remain elusive. We demonstrate that the topology of proteins with up to 250 amino acids can be determined from such density maps when combined with a computational protein folding protocol. Furthermore, we accurately reconstruct atomic detail in loop regions and amino acid side chains not visible in the experimental data. The EM-Fold algorithm assembles the secondary structure elements de novo before atomic detail is added using Rosetta. In a benchmark of 27 proteins the protocol consistently and reproducibly achieves models with RMSD values smaller than 3 Å. PMID:22405005

  6. 12. "OBSERVATION POSTS, STRUCTURAL PLANS AND DETAILS." Specifications No. OC25572; ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    12. "OBSERVATION POSTS, STRUCTURAL PLANS AND DETAILS." Specifications No. OC2-55-72; Drawing No. 60-09-12; sheet 89 of 148; file no. 1321/40, Rev. A. Very faint stamp above note reads: RECORD DRAWING - AS CONSTRUCTED. Below stamp: Contract no. 4338, no change. - Edwards Air Force Base, Air Force Rocket Propulsion Laboratory, Observation Bunkers for Test Stand 1-A, Test Area 1-120, north end of Jupiter Boulevard, Boron, Kern County, CA

  7. PROCESS WATER BUILDING, TRA605. FIRST FLOOR PLAN WITH STRUCTURAL DETAILS. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    PROCESS WATER BUILDING, TRA-605. FIRST FLOOR PLAN WITH STRUCTURAL DETAILS. FLOOR SLABS AND HATCHES. SHOWER/LOCKER ROOM. STAIRWAYS. TWENTY-INCH-THICK WALL DIVIDES SUMP AND SEAL TANK CHAMBERS FROM REST OF FLOOR. BLAW-KNOX 3150-805-3, 1/1951. INL INDEX NO. 531-0605-62-098-100659, REV. 1. - Idaho National Engineering Laboratory, Test Reactor Area, Materials & Engineering Test Reactors, Scoville, Butte County, ID

  8. A&M. TAN607. Construction detail showing structural steel framework with reinforcing ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    A&M. TAN-607. Construction detail showing structural steel framework with reinforcing steel in place prior to pouring concrete for biparting doors between hot shop and special equipment service (SES) room. Facing north. Hot shop to left, SES room to right. slot for north half of door shows at upper left of view. Date: May 21, 1954. INEEL negative no. 10548 - Idaho National Engineering Laboratory, Test Area North, Scoville, Butte County, ID

  9. Structure A, protective alarm installation details. Drawing no. H3709, revised ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Structure A, protective alarm installation details. Drawing no. H3-709, revised as-built dated August 28, 1952. Original drawing by Black & Veatch, consulting engineers, Kansas City, Missouri, prepared for the U.S. Department of the Army, Office of Engineers, Military Construction Division, Washington, D.C. dated October 1, 1951. - Travis Air Force Base, Building No. 925, W Street, Fairfield, Solano County, CA

  10. Toward Mapping the Detailed Density Structure of Classical Be Circumstellar Disks

    NASA Technical Reports Server (NTRS)

    Wisniewski, J. P.; Kowalski, A. F.; Bjorkman, K. S.; Bjorkman, J. E.

    2005-01-01

    We present the preliminary results of near contemporaneous optical and infrared spectroscopic observations of select classical Be stars. We find strong evidence of oppositely oriented V/R hydrogen line profiles in the optical versus infrared spectra of zeta Tau, and briefly discuss how sustained contemporaneous optical and infrared spectroscopic observations might enable us to trace the detailed density structure of classical Be circumstellar disks.

  11. New contrast-detail phantoms for improved precision in lesion detection measurements.

    PubMed

    Smith, S W; Insana, M F; Lopez, H

    1989-01-01

    The previous design of our ultrasound contrast-detail (C-D) phantom is limited in its ability to evaluate the quality of diagnostic ultrasound imaging systems. There is uncertainty in the contrast-detail measurements due to the single available viewing angle for each target and the resulting single realization of the ultrasound speckle pattern. Two new contrast-detail phantom designs are described which enable many independent realizations of the speckle noise for observer C-D experiments of improved precision. In the first design, a single tissue-mimicking cone is located on the axis of a tissue-mimicking cylinder. Cross-sectional images of the cone which simulate focal lesions can be obtained from any orientation by rotating the cylinder under the transducer. In the second new design, a tissue-mimicking cone is positioned in a tissue-mimicking slurry of agar/graphite spheres. Gentle stirring of the slurry and rotation of the cone produce many independent realizations of the speckle. In both new phantoms, the lesion contrast can be specified and is frequency/transducer independent.

  12. NMR crystallography of enzyme active sites: probing chemically detailed, three-dimensional structure in tryptophan synthase.

    PubMed

    Mueller, Leonard J; Dunn, Michael F

    2013-09-17

    NMR crystallography--the synergistic combination of X-ray diffraction, solid-state NMR spectroscopy, and computational chemistry--offers unprecedented insight into three-dimensional, chemically detailed structure. Initially, researchers used NMR crystallography to refine diffraction data from organic and inorganic solids. Now we are applying this technique to explore active sites in biomolecules, where it reveals chemically rich detail concerning the interactions between enzyme site residues and the reacting substrate. Researchers cannot achieve this level of detail from X-ray, NMR,or computational methodologies in isolation. For example, typical X-ray crystal structures (1.5-2.5 Å resolution) of enzyme-bound intermediates identify possible hydrogen-bonding interactions between site residues and substrate but do not directly identify the protonation states. Solid-state NMR can provide chemical shifts for selected atoms of enzyme-substrate complexes, but without a larger structural framework in which to interpret them only empirical correlations with local chemical structure are possible. Ab initio calculations and molecular mechanics can build models for enzymatic processes, but they rely on researcher-specified chemical details. Together, however, X-ray diffraction, solid-state NMR spectroscopy, and computational chemistry can provide consistent and testable models for structure and function of enzyme active sites: X-ray crystallography provides a coarse framework upon which scientists can develop models of the active site using computational chemistry; they can then distinguish these models by comparing calculated NMR chemical shifts with the results of solid-state NMR spectroscopy experiments. Conceptually, each technique is a puzzle piece offering a generous view of the big picture. Only when correctly pieced together, however, can they reveal the big picture at the highest possible resolution. In this Account, we detail our first steps in the development of

  13. Restoring Detailed Geomagnetic and Environmental Information from Continuous Sediment Paleomagnetic Measurement through Optimised Deconvolution

    NASA Astrophysics Data System (ADS)

    Xuan, C.; Oda, H.

    2013-12-01

    The development of pass-through cryogenic magnetometers has greatly improved our efficiency in collecting paleomagnetic and rock magnetic data from continuous samples such as sediment half-core sections and u-channels. During a pass-through measurement, the magnetometer sensor response inevitably convolves with remanence of the continuous sample. The convolution process results in smoothed measurement and can seriously distort the paleomagnetic signal due to differences in sensor response along different measurement axes. Previous studies have demonstrated that deconvolution can effectively overcome the convolution effect of sensor response and improve the resolution for continuous paleomagnetic data. However, the lack of an easy-to-use deconvolution tool and the difficulty in accurately measuring the magnetometer sensor response have greatly hindered the application of deconvolution. Here, we acquire reliable estimate of sensor response of a pass-through cryogenic magnetometer at the Oregon State University by integrating repeated measurements of a magnetic point source. The point source is fixed in the center of a well-shaped polycarbonate cube with 5 mm edge length, and measured at every 1 mm position along a 40-cm interval while placing the polycarbonate cube at each of the 5 × 5 grid positions over a 2 × 2 cm2 area on the cross section. The acquired sensor response reveals that cross terms (i.e. response of pick-up coil for one axis to magnetic signal along other axes) that were often omitted in previous deconvolution practices are clearly not negligible. Utilizing the detailed estimate of magnetometer sensor response, we present UDECON, a graphical tool for convenient application of optimised deconvolution based on Akaike's Bayesian Information Criterion (ABIC) minimization (Oda and Shibuya, 1996). UDECON directly reads a paleomagnetic measurement file, and allows user to view, compare, and save data before and after deconvolution. Optimised deconvolution

  14. Measurement fidelity of heart rate variability signal processing: the devil is in the details.

    PubMed

    Jarrin, Denise C; McGrath, Jennifer J; Giovanniello, Sabrina; Poirier, Paul; Lambert, Marie

    2012-10-01

    Heart rate variability (HRV) is a particularly valuable quantitative marker of the flexibility and balance of the autonomic nervous system. Significant advances in software programs to automatically derive HRV have led to its extensive use in psychophysiological research. However, there is a lack of systematic comparisons across software programs used to derive HRV indices. Further, researchers report meager details on important signal processing decisions making synthesis across studies challenging. The aim of the present study was to evaluate the measurement fidelity of time- and frequency-domain HRV indices derived from three predominant signal processing software programs commonly used in clinical and research settings. Triplicate ECG recordings were derived from 20 participants using identical data acquisition hardware. Among the time-domain indices, there was strong to excellent correspondence (ICC(avg)=0.93) for SDNN, SDANN, SDNNi, rMSSD, and pNN50. The frequency-domain indices yielded excellent correspondence (ICC(avg)=0.91) for LF, HF, and LF/HF ratio, except for VLF which exhibited poor correspondence (ICC(avg)=0.19). Stringent user-decisions and technical specifications for nuanced HRV processing details are essential to ensure measurement fidelity across signal processing software programs.

  15. Measurement fidelity of heart rate variability signal processing: The devil is in the details

    PubMed Central

    Jarrin, Denise C.; McGrath, Jennifer J.; Giovanniello, Sabrina; Poirier, Paul; Lambert, Marie

    2017-01-01

    Heart rate variability (HRV) is a particularly valuable quantitative marker of the flexibility and balance of the autonomic nervous system. Significant advances in software programs to automatically derive HRV have led to its extensive use in psychophysiological research. However, there is a lack of systematic comparisons across software programs used to derive HRV indices. Further, researchers report meager details on important signal processing decisions making synthesis across studies challenging. The aim of the present study was to evaluate the measurement fidelity of time- and frequency-domain HRV indices derived from three predominant signal processing software programs commonly used in clinical and research settings. Triplicate ECG recordings were derived from 20 participants using identical data acquisition hardware. Among the time-domain indices, there was strong to excellent correspondence (ICCavg =0.93) for SDNN, SDANN, SDNNi, rMSSD, and pNN50. The frequency-domain indices yielded excellent correspondence (ICCavg =0.91) for LF, HF, and LF/HF ratio, except for VLF which exhibited poor correspondence (ICCavg =0.19). Stringent user-decisions and technical specifications for nuanced HRV processing details are essential to ensure measurement fidelity across signal processing software programs. PMID:22820268

  16. Seismic retroftting of RC columns with RC jackets and wing walls with different structural details

    NASA Astrophysics Data System (ADS)

    Chang, Shuenn-Yih; Chen, Ting-Wei; Tran, Ngoc-Cuong; Liao, Wen-I.

    2014-06-01

    An original reinforced concrete (RC) column and four strengthened specimens, two with RC jackets and two with wing walls, were tested in this study. The original column specimen was designed to comply with older (pre-1999) design standards so that the usual detailing deficiencies in existing school buildings in Taiwan could be simulated. Two different structural details were chosen to fabricate the full-scale specimens for each retrofitting technique. The study confirmed that either RC jacketing or the installation of wing walls with two different structural details can effectively improve the stiffness and strength of an existing column. RC jacketing shows a better improvement in energy dissipation and ductility when compared to the columns with wing walls installed. This is because the two RC jacketed columns experienced a flexural failure, while a shear failure was found in the two columns with the wing walls installed, and thus led to a drastic decrease of the maximum lateral strengths and ductility. Since many factors may affect the installation of a post-installed anchor, it is better to use standard hooks to replace post-installed anchors in some specific points when using RC jacketing or installing wing walls.

  17. Imaging the internal structure of fluid upflow zones with detailed digital Parasound echosounder surveys

    NASA Astrophysics Data System (ADS)

    Spiess, V.; Zuehlsdorff, L.; von Lom-Keil, H.; Schwenk, T.

    2001-12-01

    Sites of venting fluids both with continuous and episodic supply often reveal complex surface and internal structures, which are difficult to image and cause problems to transfer results from local sampling towards a structural reconstruction and a quantification of (average) flux rates. Detailed acoustic and seismic surveys would be required to retrieve this information, but also an appropriate environment, where fluid migration can be properly imaged from contrasts to unaffected areas. Hemipelagic sediments are most suitable, since typically reflectors are coherent and of low lateral amplitude variation and structures are continuous over distances much longer than the scale of fluid migration features. During RV Meteor Cruise M473 and RV Sonne Cruise SO 149 detailed studies were carried out in the vicinity of potential fluid upflow zones in the Lower Congo Basin at 5oS in 3000 m water depth and at the Northern Cascadia Margin in 1000 m water depth. Unexpected sampling of massive gas hydrates from the sea floor as well as of carbonate concretions, shell fragments and different liveforms indicated active fluid venting in a typically hemipelagic realm. The acoustic signature of such zones includes columnar blanking, pockmark depressions at the sea floor, association with small offset faults (< 1m). A dedicated survey with closely spaced grid lines was carried out with the Parasound sediment echosounder (4 kHz), which data were digitally acquired with the ParaDigMA System for further processing and display, to image the spatial structure of the upflow zones. Due to the high data density amplitudes and other acoustic properties could be investigated in a 3D volume and time slices as well as reflector surfaces were analyzed. Pronounced lateral variations of reflection amplitudes within a complex pattern indicate potential pathways for fluid/gas migration and occurrences of near-surface gas hydrate deposits, which may be used to trace detailed surface evidence from side

  18. Toward Mapping the Detailed Density Structure of Classical Be Circumstellar Disks

    NASA Astrophysics Data System (ADS)

    Wisniewski, J. P.; Kowalski, A. F.; Bjorkman, K. S.; Bjorkman, J. E.; Carciofi, A. C.

    2007-02-01

    The first results from a near-contemporaneous optical and infrared spectroscopic observing program designed to probe the detailed density structure of classical Be circumstellar disks are presented. We report the discovery of asymmetrical infrared emission lines of He I, O I, Fe II, and the Brackett, Paschen, and Pfund series lines of H I that exhibit an opposite V/R orientation (V>R) to that observed for the optical Balmer Hα line (Vdetailed theoretical modeling, is suggested to test this hypothesis.

  19. Three-dimensional surface models of detailed lumbosacral structures reconstructed from the Visible Korean.

    PubMed

    Shin, Dong Sun; Chung, Min Suk; Park, Jin Seo; Park, Hyung Seon; Lee, Seung-Bock; Lee, Sang-Ho; Choi, Ho-Nam; Riemer, Martin; Handels, Heinz; Lee, Jong Eun; Jung, Wonsug

    2011-02-20

    Unlike volume models, surface models representing hollow, three-dimensional images have a small file size; allowing them to be displayed, rotated, and modified in real time. Therefore, surface models of lumbosacral structures can be effectively used for interactive simulation of, e.g., virtual lumbar puncture, virtual surgery of herniated lumbar discs, and virtual epidural anesthesia. In this paper, we present surface models of extensive lumbosacral structures which can be used in medical simulation systems. One-hundred and thirty-eight chosen structures included the spinal cord, lumbar and sacral nerves, vertebrae, intervertebral discs, ligaments, muscles, arteries, and skin. The structures were outlined in the sectioned images from the Visible Korean. From these outlined images, serial outlines of each structure were stacked. Adopting commercial software (3D-DOCTOR, Maya), an advanced surface reconstruction technique was applied to create a surface model of the structure. In the surface models, we observed the anatomical relationships of the lumbosacral structures (e.g., cauda equina and ligaments) in detail. Additionally, the portions of some spinal nerves that could not be outlined were drawn and added to the surface models. These constructed models will hopefully facilitate development of high quality medical simulation of the lumbosacral region. Copyright © 2010 Elsevier GmbH. All rights reserved.

  20. Formulation of probabilistic models of protein structure in atomic detail using the reference ratio method.

    PubMed

    Valentin, Jan B; Andreetta, Christian; Boomsma, Wouter; Bottaro, Sandro; Ferkinghoff-Borg, Jesper; Frellsen, Jes; Mardia, Kanti V; Tian, Pengfei; Hamelryck, Thomas

    2014-02-01

    We propose a method to formulate probabilistic models of protein structure in atomic detail, for a given amino acid sequence, based on Bayesian principles, while retaining a close link to physics. We start from two previously developed probabilistic models of protein structure on a local length scale, which concern the dihedral angles in main chain and side chains, respectively. Conceptually, this constitutes a probabilistic and continuous alternative to the use of discrete fragment and rotamer libraries. The local model is combined with a nonlocal model that involves a small number of energy terms according to a physical force field, and some information on the overall secondary structure content. In this initial study we focus on the formulation of the joint model and the evaluation of the use of an energy vector as a descriptor of a protein's nonlocal structure; hence, we derive the parameters of the nonlocal model from the native structure without loss of generality. The local and nonlocal models are combined using the reference ratio method, which is a well-justified probabilistic construction. For evaluation, we use the resulting joint models to predict the structure of four proteins. The results indicate that the proposed method and the probabilistic models show considerable promise for probabilistic protein structure prediction and related applications. Copyright © 2013 Wiley Periodicals, Inc.

  1. Detailed design of an SMA-actuated self-locking device for rotary feed structure

    NASA Astrophysics Data System (ADS)

    Xiaoyu, Qin; Xiaojun, Yan; Xiaoyong, Zhang; Weibing, Wang; Lianghai, Li

    2016-03-01

    This paper presents a detailed design of a locking device which is used to lock the rotary feed structure of a space-borne microwave radiometer during the launching stage. This locking device employs two redundant shape memory alloy (SMA) wires as the actuating elements, uses a self-locking structure to achieve the locking function and a step structure to ensure a safety clearance after release. Based on the design concept, preliminary design of the locking/release unit and the clamp unit are performed. Then, a more accurate simulation of the release process and the cyclic property of the device is carried out by using an improved Brinson’s SMA constitutive model and a heat transfer equation. After the design and simulation, four prototypes are fabricated and their performance tests are carried out to evaluate the self-locking property, lifetime and thermal tolerance.

  2. A Detailed Study on the Low-Energy Structures of Charged Colloidal Clusters.

    PubMed

    Cruz, S M A; Marques, J M C

    2016-04-07

    The target of this investigation is the systematic characterization of the low-energy structures of charged colloidal clusters that may be important to understand the self-assembling process of biomolecules. The aggregation of charged colloidal particles is governed by the attractive short-ranged Morse potential and the Yukawa repulsive tail to describe the long-range charge effect. A global optimization strategy, based on our own evolutionary algorithm, was adopted to discover the low-energy structures of colloidal clusters composed of up to 20 particles. A detailed analysis of the low-energy structures involving charged particles shows that the appearance of the Bernal spiral as the most stable motif occurs, first, at N = 6, but it is favored for larger clusters (N ≥ 13); for 6 ≤ N ≤ 12, there is a competition between the spiral (which is favored for higher charges) and more spherical-like structures. Finally, we study binary clusters composed by two sets of differently charged colloidal particles. Although a great diversity of low-energy structures is observed (especially for aggregates with one of the components in excess), the global minimum is disputed by three structural motifs depending on the composition of the cluster and, in some cases, on the range of the Morse potential.

  3. The E-ELT project: the telescope main structure detailed design study

    NASA Astrophysics Data System (ADS)

    Marchiori, Gianpietro; Busatta, Andrea; Ghedin, Leonardo; De Lorenzi, Simone

    2012-09-01

    The European Extremely Large Telescope (E-ELT) is the biggest telescope in the world. Within the Detailed Design activities, ESO has awarded EIE GROUP (European Industrial Engineering) a contract for the Design of the Main Structure to the point where the concept of the telescope has been consolidated, from a construction point of view. All the Design activities have been developed in order to create an integrated system in terms of functionality and performance, while the engineering activities have been performed with the aim of obtaining a telescope that can be built, transported, integrated, with a reduced maintainability.

  4. Van Allen Probe Measurements of the Scale Sizes and Detailed Properties of EMIC Waves

    NASA Astrophysics Data System (ADS)

    Blum, L. W.; Bonnell, J. W.; Agapitov, O. V.; Mozer, F.

    2016-12-01

    Electromagnetic ion cyclotron (EMIC) waves are able to resonate with MeV electrons and cause precipitation loss of radiation belt electrons. EMIC waves can provide a strong source of electron pitch angle diffusion, but the waves are often quite localized - thus the spatial extents of these waves can have a large effect on their overall scattering efficiency. Using measurements from the dual Van Allen Probes, we characterize the spatial and temporal extents of EMIC wave active regions and how these depend on local time, radial distance, and wave properties (e.g. amplitude, frequency). Analysis of the detailed wave properties is also performed; we estimate the active region and coherence scales of EMIC waves and examine nonlinear features and parallel electric fields present in some events. These investigations help determine the nature of EMIC wave-particle interactions and support more accurate quantification of their effects on the outer radiation belt.

  5. A detailed procedure for measuring turbulent velocity fluctuations using constant-voltage anemometry

    NASA Astrophysics Data System (ADS)

    Mohammed-Taifour, Abdelouahab; Weiss, Julien; Sadeghi, Atabak; Vétel, Jérôme; Jondeau, Emmanuel; Comte-Bellot, Geneviève

    2015-09-01

    A detailed procedure to use a constant-voltage anemometer (CVA) for the accurate measurement of turbulent flows is proposed. The procedure is based on the usual small-perturbation analysis of hot-wire signals. It consists in three steps: (1) the calibration of internal elements, required to estimate the two main electrical parameters of the CVA circuitry that are needed in the data analysis, (2) a flow calibration to relate the CVA output voltage and the hot-wire time constant to the flow velocity, and (3) a data-processing algorithm to recover the fluctuating flow quantities from the output voltage. The procedure is tested in two classical turbulent flows: a zero-pressure-gradient boundary layer and a round jet. In both cases, the CVA results are shown to be essentially indistinguishable from the results obtained with a research-grade constant-temperature anemometer.

  6. Detailed heat transfer coefficient measurements and thermal analysis at engine conditions of a pedestal with fillet radii

    SciTech Connect

    Wang, Z.; Ireland, P.T.; Jones, T.V.

    1995-04-01

    Short pin-fin and pin-fin arrays are frequently used in turbine blade internal cooling systems to enhance cooling and stiffen the structure. The present work has shown that a knowledge of the detailed heat transfer coefficient distribution is required to predict the cooling effect of such devices accurately. The heat flow process has been numerically modeled at typical engine conditions with the detailed heat transfer distribution measured by the transient heat transfer method being used as the thermal boundary conditions. The heat transfer coefficient over the surface of a pedestal with fillet radii has been measured using thermochromic liquid crystals and the transient heat transfer method. The tests were performed at engine representative Reynolds numbers for a geometry typical of those used in turbine blade cooling systems. The heat conduction process that occurs in the engine was subsequently modeled numerically with a finite element discretization of the solid pedestal. The measured heat transfer coefficients were used to derive the exact boundary conditions applicable to the engine. The temperature field within the pedestal, calculated using the correct heat transfer coefficient distribution, is compared to that calculated using an area-averaged heat transfer coefficient. Metal temperature differences of 90 K are predicted across the blade wall.

  7. High-resolution crystal structure reveals molecular details of target recognition by bacitracin

    PubMed Central

    Economou, Nicoleta J.; Cocklin, Simon; Loll, Patrick J.

    2013-01-01

    Bacitracin is a metalloantibiotic agent that is widely used as a medicine and feed additive. It interferes with bacterial cell-wall biosynthesis by binding undecaprenyl-pyrophosphate, a lipid carrier that serves as a critical intermediate in cell wall production. Despite bacitracin’s broad use, the molecular details of its target recognition have not been elucidated. Here we report a crystal structure for the ternary complex of bacitracin A, zinc, and a geranyl-pyrophosphate ligand at a resolution of 1.1 Å. The antibiotic forms a compact structure that completely envelopes the ligand’s pyrophosphate group, together with flanking zinc and sodium ions. The complex adopts a highly amphipathic conformation that offers clues to antibiotic function in the context of bacterial membranes. Bacitracin’s efficient sequestration of its target represents a previously unseen mode for the recognition of lipid pyrophosphates, and suggests new directions for the design of next-generation antimicrobial agents. PMID:23940351

  8. Detailed analysis of surface asperity deformation mechanism in diffusion bonding of steel hollow structural components

    NASA Astrophysics Data System (ADS)

    Zhang, C.; Li, H.; Li, M. Q.

    2016-05-01

    This study focused on the detailed analysis of surface asperity deformation mechanism in similar diffusion bonding as well as on the fabrication of high quality martensitic stainless steel hollow structural components. A special surface with regular patterns was processed to be joined so as to observe the extent of surface asperity deformation under different bonding pressures. Results showed that an undamaged hollow structural component has been obtained with full interfacial contact and the same shear strength to that of base material. Fracture surface characteristic combined with surface roughness profiles distinctly revealed the enhanced surface asperity deformation as the applied pressure increases. The influence of surface asperity deformation mechanism on joint formation was analyzed: (a) surface asperity deformation not only directly expanded the interfacial contact areas, but also released deformation heat and caused defects, indirectly accelerating atomic diffusion, then benefits to void shrinkage; (b) surface asperity deformation readily introduced stored energy difference between two opposite sides of interface grain boundary, resulting in strain induced interface grain boundary migration. In addition, the influence of void on interface grain boundary migration was analyzed in detail.

  9. On the effect of accelerated winds on the wave growth through detailed laboratory measurements.

    NASA Astrophysics Data System (ADS)

    Ocampo-Torres, Francisco J.; Branger, Hubert; Osuna, Pedro; Hernández, Aldo

    2013-04-01

    The possible influence of accelerated winds on air-water momentum fluxes is being studied through detailed laboratory measurements in a large wind-wave flume. Wind stress over the water surface, waves and surface drift are measured in the 40m long wind-wave tank at IRPHE, Marseille. While momentum fluxes are estimated directly through the eddy correlation method in a station about the middle of the tank, they provide information corresponding to rather short non-dimensional fetch not previously reported. Wave evolution along the tank is determined through a series of wave gauges, and the wind-induced surface drift is obtained at one of the first measuring stations at the beginning of the tank. At each experimental run very low wind was on (about 1m/s) for a certain period and suddenly it was constantly accelerated to reach about 13 m/s (as well as 8 and 5 m/s during different runs) in about 15 sec to as long as 600 sec. The wind was kept constant at that high speed for 2 to 10 min, and then suddenly and constantly decelerate to 0. Data from the constant high winds provided us with reference equilibrium conditions for at least 3 different wind speed. We, nevertheless, focus in the recordings while wind was being constantly accelerated expecting some contribution to the understanding of gustiness, the implied wind wave growth and the onset of surface drift. Wind-wave growth is observed to lag behind the wind stress signal, and furthermore, a two regime wind stress is noticed, apparently well correlated with a) the incipient growth and appearance of the first waves and b) the arrival of waves from the up-wind section of the tank. Results of non-dimensional wave energy as a function of non-dimensional fetch represent an extension of at least 2 decades shorter non-dimensional fetch to the wave growth curves typically found in the literature. The linear tendency of wave growth compares very well only when wind is reaching its maximum, while during the accelerated wind

  10. An Empirical Investigation Of Variability In Contrast-Detail Diagram Measurements

    NASA Astrophysics Data System (ADS)

    Loo, Leh-Nien D.; Doi, Kunio; Ishida, Masamitsu; Metz, Charles E.; Chan, Heang-Ping; Higashida, Yoshiharu; Kodera, Yoshie

    1983-12-01

    The contrast-detail (C-D) diagram has been used widely yin the evaluation of imaging systems including screen-film combinations, computed tomography, and digital radiography. Despite its apparent simplicity and efficiency in generating observer performance data, the relationship between this method and the more rigorous ROC or forced-choice procedures is not well understood. With a high-quality image processing/simulation system, we made images by superimposing digitally simulated square patterns on radiographic noise. We then studied the statistical variability in the C-D diagram due to within- and between-reader differences, and the effect of different numbers of image samples. Results indicate that the percent standard deviations due to each of these variations are about 10-20%. We also compared the visibility thresholds measured by the C-D diagram method and by an 18-alternative forced-choice (18AFC) procedure. Although the thresholds defined in these two methods are fundamentally different, we found that the threshold contrasts measured by the two procedures have similar values.

  11. Detailed Measurements of Turbulent Rayleigh-Taylor Mixing at Large and Small Atwood Numbers

    SciTech Connect

    Malcolm J. Andrews, Ph.D.

    2004-12-14

    This project has two major tasks: Task 1. The construction of a new air/helium facility to collect detailed measurements of Rayleigh-Taylor (RT) mixing at high Atwood number, and the distribution of these data to LLNL, LANL, and Alliance members for code validation and design purposes. Task 2. The collection of initial condition data from the new Air/Helium facility, for use with validation of RT simulation codes at LLNL and LANL. Also, studies of multi-layer mixing with the existing water channel facility. Over the last twelve (12) months there has been excellent progress, detailed in this report, with both tasks. As of December 10, 2004, the air/helium facility is now complete and extensive testing and validation of diagnostics has been performed. Currently experiments with air/helium up to Atwood numbers of 0.25 (the maximum is 0.75, but the highest Reynolds numbers are at 0.25) are being performed. The progress matches the project plan, as does the budget, and we expect this to continue for 2005. With interest expressed from LLNL we have continued with initial condition studies using the water channel. This work has also progressed well, with one of the graduate Research Assistants (Mr. Nick Mueschke) visiting LLNL the past two summers to work with Dr. O. Schilling. Several journal papers are in preparation that describe the work. Two MSc.'s have been completed (Mr. Nick Mueschke, and Mr. Wayne Kraft, 12/1/03). Nick and Wayne are both pursuing Ph.D.s' funded by this DOE Alliances project. Presently three (3) Ph.D. graduate Research Assistants are supported on the project, and two (2) undergraduate Research Assistants. During the year two (2) journal papers and two (2) conference papers have been published, ten (10) presentations made at conferences, and three (3) invited presentations.

  12. Measuring the IMF and Detailed Abundance Patterns from the Integrated Light of Old Stellar Systems

    NASA Astrophysics Data System (ADS)

    Conroy, Charlie

    The spectral energy distributions (SEDs) of unresolved stellar systems holds key information regarding the detailed abundance pattern, star formation history, dust properties, and initial mass function (IMF) of the underlying stellar population(s). This information can only be extracted with the aid of stellar population synthesis (SPS) models. Such models have been employed to estimate basic properties such as the star formation rate, metallicity (Z, and in certain contexts, alpha-enhancement), and total stellar mass (assuming an IMF). However, much more information is available in the SED than can be extracted by the current generation of SPS models because existing models are plagued by incomplete and poorly calibrated ingredients. The proposers request funds to develop a next generation SPS model capable of measuring the IMF and detailed abundance patterns from the SEDs of composite stellar systems. In particular, we intend to develop an SPS model that makes accurate predictions for the SEDs (from 0.1-3mu m at a resolving power of ~5,000) of composite systems as a function of the IMF, stellar age, metallicity, and individual elemental abundances (including C, N, O, Na, Mg, Ca, Ti, Cr, Mn, Fe, Sr, and Ba). This will require the construction of a new synthetic stellar spectral library and a new isochrone library. This new model will be the first to make predictions for the full SED shape as a function of individual abundance ratios, age, and the IMF. We will extensively calibrate the model predictions against data on individual stars and globular clusters. The new model will be essential for interpreting optical-NIR spectra obtained from the James Webb Space Telescope as well as both present and future ground-based facilities.

  13. Congruent Strategies for Carbohydrate Sequencing. 1. Mining Structural Details by MSn

    PubMed Central

    Ashline, David; Singh, Suddham; Hanneman, Andy; Reinhold, Vernon

    2005-01-01

    This report is the first in a series of three focused on establishing congruent strategies for carbohydrate sequencing. The reports are divided into (i) analytical considerations that account for all aspects of small oligomer structure by MSn disassembly, (ii) database support using an ion fragment library and associated tools for highthroughput analysis, and (iii) a concluding algorithm for defining oligosaccharide topology from MSn disassembly pathways. The analytical contribution of this first report explores the limits of structural detail exposed by ion trap mass spectrometry with samples prepared as methyl derivatives and analyzed as metal ion adducts. This data mining effort focuses on correlating the fragments of small oligomers to stereospecific glycan structures, an outcome attributed to a combination of metal ion adduction and analyte conformation. Facile glycosidic cleavage introduces a point of lability (pyranosyl-1-ene) that upon collisional activation initiates subsequent ring fragmentation. Product masses and ion intensities vary with interresidue linkage, branching position, and monomer stereochemistry. Excessive fragmentation is the property of small oligomers where collisional energy within a smaller number of oscillators dissipates through extensive fragmentation. The procedures discussed in this report are unified into a singular strategy using an ion trap mass spectrometer with the sensitivity expected for electron multiplier detection. Although a small set of structures have been discussed, the basic principles considered are fully congruent, with ample opportunities for expansion. PMID:16194086

  14. Most Detailed Direct Measurements Yet of Turbidity Currents in the Deep Ocean: Monterey Coordinated Canyon Experiment

    NASA Astrophysics Data System (ADS)

    Paull, C. K.; Anderson, K.; Barry, J. P.; Caress, D. W.; Chaffey, M. R.; Gales, J. A.; Gwiazda, R.; Kieft, B.; Lundsten, E. M.; Maier, K. L.; McCann, M. P.; McGann, M.; O'Reilly, T. C.; Parsons, D. R.; Rosenberger, K. J.; Sumner, E.; Talling, P. J.; Xu, J.

    2016-12-01

    Submarine sediment gravity flows (turbidity currents) are among the most important sediment transport processes on Earth, yet there are remarkably few direct measurements of these events in action. The ongoing multi-institution Coordinated Canyon Experiment (CCE) is providing detailed measurements of turbidity currents using multiple sensors and sediment traps deployed in the axis of Monterey Canyon, offshore California, in 6-month long deployments from October 2015 to April 2017 together with seafloor sampling and repeated mapping of seafloor morphology. No previous study has deployed such a dense array of sensors along a turbidity current pathway. Instrumentation includes: an array of 6 moorings carrying downward looking acoustic Doppler current profilers (ADCP) and sediment traps distributed along the canyon axis from 270 to 1,850 m water depth; a benthic instrument node at 1,840 m holding ADCPs of three different frequencies recording on a common time base, as well as salinity, temperature, and turbidity sensors; a McLane profiler at 1,830 m monitoring the lower 500 m of the water column; an array of benthic event detectors (smart boulders) that record their transport within the base of a flow; and precision triangulation beacons to assess creep within the canyon floor. Repeated mapping of the canyon floor at nested grid resolutions ranging from 1-m to 1-cm is being conducted to understand changes in canyon floor morphology. The first 6-month long deployment has been completed and 8 sediment transport events recorded. Seven of these events were restricted to <520 m water depths. However, on January 15th 2016 a sediment-laden turbidity flow ran out for >50 km from <279 m to >1,860 m water depth with an average velocity of 5.4 m/sec. Individual moorings and instruments moved down-canyon up to 7.8 km during this event. The novel instrument array and mapping tools have successfully recorded the down-canyon evolution of the powerful flow in spectacular detail.

  15. Probing the Detailed Seismic Velocity Structure of Subduction Zones Using Advanced Seismic Tomography Methods

    NASA Astrophysics Data System (ADS)

    Zhang, H.; Thurber, C. H.

    2005-12-01

    Subduction zones are one of the most important components of the Earth's plate tectonic system. Knowing the detailed seismic velocity structure within and around subducting slabs is vital to understand the constitution of the slab, the cause of intermediate depth earthquakes inside the slab, the fluid distribution and recycling, and tremor occurrence [Hacker et al., 2001; Obara, 2002].Thanks to the ability of double-difference tomography [Zhang and Thurber, 2003] to resolve the fine-scale structure near the source region and the favorable seismicity distribution inside many subducting slabs, it is now possible to characterize the fine details of the velocity structure and earthquake locations inside the slab, as shown in the study of the Japan subduction zone [Zhang et al., 2004]. We further develop the double-difference tomography method in two aspects: the first improvement is to use an adaptive inversion mesh rather than a regular inversion grid and the second improvement is to determine a reliable Vp/Vs structure using various strategies rather than directly from Vp and Vs [see our abstract ``Strategies to solve for a better Vp/Vs model using P and S arrival time'' at Session T29]. The adaptive mesh seismic tomography method is based on tetrahedral diagrams and can automatically adjust the inversion mesh according to the ray distribution so that the inversion mesh nodes are denser where there are more rays and vice versa [Zhang and Thurber, 2005]. As a result, the number of inversion mesh nodes is greatly reduced compared to a regular inversion grid with comparable spatial resolution, and the tomographic system is more stable and better conditioned. This improvement is quite valuable for characterizing the fine structure of the subduction zone considering the highly uneven distribution of earthquakes within and around the subducting slab. The second improvement, to determine a reliable Vp/Vs model, lies in jointly inverting Vp, Vs, and Vp/Vs using P, S, and S

  16. Global Snow Mass Measurements and the Effect of Stratigraphic Detail on Inversion of Microwave Brightness Temperatures

    NASA Astrophysics Data System (ADS)

    Richardson, Mark; Davenport, Ian; Gurney, Robert

    2014-05-01

    Snow provides large seasonal storage of freshwater, and information about the distribution of snow mass as snow water equivalent (SWE) is important for hydrological planning and detecting climate change impacts. Large regional disagreements remain between estimates from reanalyses, remote sensing and modelling. Assimilating passive microwave information improves SWE estimates in many regions, but the assimilation must account for how microwave scattering depends on snow stratigraphy. Physical snow models can estimate snow stratigraphy, but users must consider the computational expense of model complexity versus acceptable errors. Using data from the National Aeronautics and Space Administration Cold Land Processes Experiment and the Helsinki University of Technology microwave emission model of layered snowpacks, it is shown that simulations of the brightness temperature difference between 19 and 37 GHz vertically polarised microwaves are consistent with advanced microwave scanning radiometer-earth observing system and special sensor microwave imager retrievals once known stratigraphic information is used. Simulated brightness temperature differences for an individual snow profile depend on the provided stratigraphic detail. Relative to a profile defined at the 10-cm resolution of density and temperature measurements, the error introduced by simplification to a single layer of average properties increases approximately linearly with snow mass. If this brightness temperature error is converted into SWE using a traditional retrieval method, then it is equivalent to ±13 mm SWE (7 % of total) at a depth of 100 cm. This error is reduced to ±5.6 mm SWE (3 % of total) for a two-layer model.

  17. Measurement of angle and axis of rotation in a carousel interferometer: a detailed analysis

    SciTech Connect

    Hussain, Ghazanfar; Ikram, Masroor

    2010-02-20

    A detailed analysis of a carousel interferometer is presented for the measurement of an unknown angle and axis of rotation. The technique exploits a set of compensator glass plates and a right-angle prism that is placed in each of the two arms of the interferometer. The two sets are placed at the same rotational stage, while the end mirrors of the interferometer are static. When rotation takes place, individual and relative optical path differences are generated in the two beams of the interferometer. The generated phase differences contribute toward finding the angle and axis of rotation. The analysis is presented for any initial position of the interferometer, i.e., the radial vector from the axis of rotation to the apex of one of the prisms used. The results show the slight variations in the error and nonlinearity when different parameters are manipulated. Moreover, the trade-off between the maximum size of the prisms and the radial distances are also presented.

  18. Deconvolution-Based CT and MR Brain Perfusion Measurement: Theoretical Model Revisited and Practical Implementation Details.

    PubMed

    Fieselmann, Andreas; Kowarschik, Markus; Ganguly, Arundhuti; Hornegger, Joachim; Fahrig, Rebecca

    2011-01-01

    Deconvolution-based analysis of CT and MR brain perfusion data is widely used in clinical practice and it is still a topic of ongoing research activities. In this paper, we present a comprehensive derivation and explanation of the underlying physiological model for intravascular tracer systems. We also discuss practical details that are needed to properly implement algorithms for perfusion analysis. Our description of the practical computer implementation is focused on the most frequently employed algebraic deconvolution methods based on the singular value decomposition. In particular, we further discuss the need for regularization in order to obtain physiologically reasonable results. We include an overview of relevant preprocessing steps and provide numerous references to the literature. We cover both CT and MR brain perfusion imaging in this paper because they share many common aspects. The combination of both the theoretical as well as the practical aspects of perfusion analysis explicitly emphasizes the simplifications to the underlying physiological model that are necessary in order to apply it to measured data acquired with current CT and MR scanners.

  19. Crystal Structures of a Poplar Xyloglucan Endotransglycosylase Reveal Details of Transglycosylation Acceptor Binding

    PubMed Central

    Johansson, Patrik; Brumer, Harry; Baumann, Martin J.; Kallas, Åsa M.; Henriksson, Hongbin; Denman, Stuart E.; Teeri, Tuula T.; Jones, T. Alwyn

    2004-01-01

    Xyloglucan endotransglycosylases (XETs) cleave and religate xyloglucan polymers in plant cell walls via a transglycosylation mechanism. Thus, XET is a key enzyme in all plant processes that require cell wall remodeling. To provide a basis for detailed structure–function studies, the crystal structure of Populus tremula x tremuloides XET16A (PttXET16A), heterologously expressed in Pichia pastoris, has been determined at 1.8-Å resolution. Even though the overall structure of PttXET16A is a curved β-sandwich similar to other enzymes in the glycoside hydrolase family GH16, parts of its substrate binding cleft are more reminiscent of the distantly related family GH7. In addition, XET has a C-terminal extension that packs against the conserved core, providing an additional β-strand and a short α-helix. The structure of XET in complex with a xyloglucan nonasaccharide, XLLG, reveals a very favorable acceptor binding site, which is a necessary but not sufficient prerequisite for transglycosylation. Biochemical data imply that the enzyme requires sugar residues in both acceptor and donor sites to properly orient the glycosidic bond relative to the catalytic residues. PMID:15020748

  20. Porous electrode apparatus for electrodeposition of detailed metal structures or microelectronic interconnections

    DOEpatents

    Griffiths, Stewart K.; Nilson, Robert H.; Hruby, Jill M.

    2002-01-01

    An apparatus and procedure for performing microfabrication of detailed metal structures by electroforming metal deposits within small cavities. Two primary areas of application are: the LIGA process which manufactures complex three-dimensional metal parts and the damascene process used for electroplating line and via interconnections of microelectronic devices. A porous electrode held in contact or in close proximity with a plating substrate or mold top to ensure one-dimensional and uniform current flow into all mold cavities is used. Electrolyte is pumped over the exposed surface of the porous electrode to ensure uniform ion concentrations at this external surface. The porous electrode prevents electrolyte circulation within individual mold cavities, avoiding preferential enhancement of ion transport in cavities having favorable geometries. Both current flow and ion transport are one-dimensional and identical in all mold cavities, so all metal deposits grow at the same rate eliminating nonuniformities of the prior art.

  1. Crystal structure of listeriolysin O reveals molecular details of oligomerization and pore formation

    NASA Astrophysics Data System (ADS)

    Köster, Stefan; van Pee, Katharina; Hudel, Martina; Leustik, Martin; Rhinow, Daniel; Kühlbrandt, Werner; Chakraborty, Trinad; Yildiz, Özkan

    2014-04-01

    Listeriolysin O (LLO) is an essential virulence factor of Listeria monocytogenes that causes listeriosis. Listeria monocytogenes owes its ability to live within cells to the pH- and temperature-dependent pore-forming activity of LLO, which is unique among cholesterol-dependent cytolysins. LLO enables the bacteria to cross the phagosomal membrane and is also involved in activation of cellular processes, including the modulation of gene expression or intracellular Ca2+ oscillations. Neither the pore-forming mechanism nor the mechanisms triggering the signalling processes in the host cell are known in detail. Here, we report the crystal structure of LLO, in which we identified regions important for oligomerization and pore formation. Mutants were characterized by determining their haemolytic and Ca2+ uptake activity. We analysed the pore formation of LLO and its variants on erythrocyte ghosts by electron microscopy and show that pore formation requires precise interface interactions during toxin oligomerization on the membrane.

  2. Structural Unemployment: Theory and Measurement.

    ERIC Educational Resources Information Center

    Penz, G. Peter

    The purpose of this monograph is to present a theoretical framework useful for measuring structural unemployment. Developed on the basis of a literature review, this framework was applied to Canadian data. The approach which explains structural unemployment in terms of the causes of labor displacement is inadequate because it ignores impediments…

  3. Measurement of Family Affective Structure.

    ERIC Educational Resources Information Center

    Lowman, Joseph

    1980-01-01

    Three studies demonstrate that the Inventory of Family Feelings, a measure of family affective structure, has high reliability and construct and concurrent validity. It is appropriate for affective comparisons by age, sex, and ordinal position of children and for measuring change after family or marital therapy, or after predictable stress…

  4. Possibility of supervision over detailed structure of ocean currents by MODIS

    NASA Astrophysics Data System (ADS)

    Sklyarov, V. E.

    2008-02-01

    The report focuses on the analysis of the detail structure of ocean currents in areas of dust storms distribution or intensive phytoplankton's development. Dust storms represent the global phenomenon occurring regularly and, thus, atmospheric streams transfer a significant amount of the sand and dust (more than 2000 million tons) from deserts of Gobi, Sahara, Namibia, and Arabian Peninsula etc. The dust from Sahara achieves Caribbean Sea and southeast areas of USA for 5-7 days, and traces of the Asian dust storm, which have crossed Pacific Ocean, were found out in Great Lakes. For the purposes of our research the influence of sand and a dust dropping out from atmosphere on optical properties of the top layer of the ocean is represented especially significant. We shall note, that this question is poorly covered in the scientific literature. On our data, there are only separate certificates that return dispersion in green area of a spectrum for the top layer of the ocean is considerably increased after passage of a dust storm. It occurs due to saturation of the ocean top layer sand particles were sunlight diffusion is good. On the other hand, these particles, being a passive tracer, are easily involved by separate jets of currents in local circulation. These factors create a real basis for space observations on details mesoscale ocean circulation. As a trial experiment, author of the report have leaded the multispectral analysis data from MODIS (satellite AQUA), received on a northwest part Indian Ocean and Gulf of Aden. Results of the analysis confirm the made hypothesis.

  5. Detailed structural features of lipopolysaccharide glycoforms in nontypeable Haemophilus influenzae strain 2019.

    PubMed

    Engskog, Mikael K R; Deadman, Mary; Li, Jianjun; Hood, Derek W; Schweda, Elke K H

    2011-07-15

    We have investigated the structure of the lipopolysaccharide (LPS) of nontypeable Haemophilus influenzae (NTHi) strain 2019, a prototype strain that is used for studies of NTHi biology and disease. Analysis of LPS from wild type and lex2B, lpt3 and pgm mutant strains using NMR techniques and ESI-MS on O-deacylated LPS and core oligosaccharide material (OS), as well as ESI-MS(n) on permethylated dephosphorylated OS, confirmed the previously established structure in which lactose is linked to the proximal heptose (HepI) of the conserved triheptosyl inner-core moiety, l-α-D-Hepp-(1→2)-[PEtn→6]-l-α-D-Hepp-(1→3)-l-α-D-Hepp-(1→5)-[PPEtn→4]-α-Kdo-(2→6)-lipid A. Importantly, our data provide further structural detail whereby extensions from the middle heptose (HepII) are now characterized as β-D-Galp-(1→4)-β-D-Glcp-(1→4)-α-D-Glcp-(1→3 and truncated versions thereof. PEtn substitutes O-3 of the distal heptose (HepIII) of the inner-core moiety. This PEtn substituent was absent in the lpt3 mutant indicating that Lpt3 is the transferase required to add PEtn to the distal heptose. Interestingly, in the lex2B mutant strain HepIII was found to be substituted at O-2 by β-D-Glcp which, in turn, can be further extended. Contrary to previous findings, LPS of the pgm mutant strain contained minor glycoforms having β-D-Glcp linked to O-4 of HepI and also glycoforms with an additional PEtn which could be assigned to HepIII. Acetate groups and one glycine residue further substitute HepIII in NTHi 2019. Copyright © 2011 Elsevier Ltd. All rights reserved.

  6. Detailed gravity mapping of the Panther Mountain circular structure, Catskill Mountains, New York

    SciTech Connect

    Isachsen, Y.W. ); Revetta, F.A. )

    1993-03-01

    The Panther Mountain circular structure is located in the Catskill Mountains near the eastern edge of the Allegheny Plateau where depth through the sedimentary section to basement is about 3200 m. The structure is distinguished from the rest of the Plateau only by its physiography. It is a circular mountain mass, 10 km in diameter, defined by an anomalous annular drainage pattern formed by Esopus Creek and its tributary Woodland Creek. Because of pervasive fluvial cross bedding in the sedimentary pile, the authors were unable to determine whether the structure is slightly domical, sightly basinal, or unwarped. North-south and east-west gravity profiles were next made and modeled to look for a subsurface explanation for the structure. The only computed profiles that matched the measured values were those for a shallowly-buried meteorite crater with its underlying breccia lens, lying beneath the Panther Mountain. Renewed interest in the structure led them to make 125 new gravity measurements, in a study that is continuing. Gravity values are corrected using the International Gravity Formula of 1967 and densities of 2.67 and 2.50 gms/cm[sup 3]. Terrain corrections were computed using an inner radius of .895 km and an outer radius of 166.70 km. The complete Bouguer gravity anomaly was separated into its regional and residual components to obtain a third order residual gravity map for computer modeling. The residual gravity map confirms the earlier detected gravity low and leaves the buried meteorite crater model as a viable model.

  7. The detailed crystal and electronic structures of the cotunnite-type ZrO2

    NASA Astrophysics Data System (ADS)

    Zhang, Yan; Duan, Li; Ji, Vincent

    2016-07-01

    The detailed crystal and orbital-decomposed electronic structures of cotunnite-type ZrO2 have been investigated by using the first-principles projector augmented wave (PAW) potential within the generalized gradient approximation as well as taking into account on-site Coulomb repulsive interaction (GGA+U). The optimized structure shows that the OI and OII anions are surrounded by an arbitrary tetrahedron of four Zr cations and an arbitrary pentahedron of five Zr cations, respectively, in turn, the Zr cation is surrounded by an arbitrary tetrakaidecahedron formed by nine oxygen ligands. Although one more Zr cation is coordinated to OII, the larger bond lengths between OII and its adjacent five Zr cations (dOII-Zr) than those between OI and its adjacent four Zr cations (dOI-Zr) makes density of states (DOS) of s and three p (px , py and pz) states of the OII anion driving down in lower energy region and driving up in higher energy region. No crystal-field splitting is observed between three p (px , py and pz) states of anions OI and OII (between three p (px , py and pz) states and five d (dxy , dyz , dxz , dz2 and dx2-y2) states of cation Zr) is resulted from the arrangements of the surrounding cations (anions) do not have any symmetry. The additional covalent character upon Zr-O ionic bonds is attributed to the hybridization of itinerant Zr(5s) and less filled Zr(4d) states to the separated O(2s) and O(2p) states.

  8. Unveiling the Detailed Density and Velocity Structures of the Protostellar Core B335

    NASA Astrophysics Data System (ADS)

    Kurono, Yasutaka; Saito, Masao; Kamazaki, Takeshi; Morita, Koh-Ichiro; Kawabe, Ryohei

    2013-03-01

    We present an observational study of the protostellar core B335 harboring a low-mass Class 0 source. The observations of the H13CO+(J = 1-0) line emission were carried out using the Nobeyama 45 m telescope and Nobeyama Millimeter Array. Our combined image of the interferometer and single-dish data depicts detailed structures of the dense envelope within the core. We found that the core has a radial density profile of n(r)vpropr -p and a reliable difference in the power-law indices between the outer and inner regions of the core: p ≈ 2 for r >~ 4000 AU and p ≈ 1.5 for r <~ 4000 AU. The dense core shows a slight overall velocity gradient of ~1.0 km s-1 over the scale of 20, 000 AU across the outflow axis. We believe that this velocity gradient represents a solid-body-like rotation of the core. The dense envelope has a quite symmetrical velocity structure with a remarkable line broadening toward the core center, which is especially prominent in the position-velocity diagram across the outflow axis. The model calculations of position-velocity diagrams do a good job of reproducing observational results using the collapse model of an isothermal sphere in which the core has an inner free-fall region and an outer region conserving the conditions at the formation stage of a central stellar object. We derived a central stellar mass of ~0.1 M ⊙, and suggest a small inward velocity, v_{r ≥ r_inf}˜ 0 km s^{-1} in the outer core at >~ 4000 AU. We concluded that our data can be well explained by gravitational collapse with a quasi-static initial condition, such as Shu's model, or by the isothermal collapse of a marginally critical Bonnor-Ebert sphere.

  9. STScI-PRC95-30 HUBBLE SEES DETAILED NEW STRUCTURES IN THREE RADIO GALAXIES

    NASA Technical Reports Server (NTRS)

    2002-01-01

    These Hubble Space Telescope images, combined with radio maps produced by the Very Large Array Radio Interferometer (blue contour lines), show surprisingly varied and intricate structures of gas and stars that suggest the mechanisms powering radio galaxies are more complex than thought previously. The bizarre, never before seen detail may be a combination of light from massive star forming regions, small satellite dwarf galaxies, and bow shocks caused by jets of hot gas blasted out of the galaxies' cores by suspected black holes. [LEFT] - 3C265. Hubble resolves numerous bright star clusters or dwarf 'satellite' galaxies surrounding a bright central compact structure. The line corresponds to the axis of the galaxy's radio emissions, which unlike other radio galaxies, is in a different direction from the optical region. The star forming regions might result from a collision between galaxies. The jet that produces the radio emissions might have further intensified star formation. [CENTER] - 3C324. A number of small interacting components are distributed roughly along the radio axis in this source. Comparison of the Hubble image with that from the United Kingdom Infrared Telescope suggests that the central regions of this galaxy are obscured by a large dust lane. [RIGHT] - 3C368. One of the best studied radio galaxies, this image is composed of a very smooth cigar-shaped emission region closely aligned with the radio axis, upon which is superimposed a string of bright knots that might be stars or dust. This suggests that a jet of high speed gas, presumably ejected from a black hole at the core of the galaxy, might be triggering star formation along its path. Credit: M. Longair (Cambridge University, England), NASA, and NRAO

  10. A Detailed Study of the Structure of the Nested Planetary Nebula, Hb 12, the Matryoshka Nebula

    NASA Astrophysics Data System (ADS)

    Clark, D. M.; López, J. A.; Edwards, M. L.; Winge, C.

    2014-11-01

    We present near-IR, integral field spectroscopic observations of the planetary nebula (PN) Hb 12 using Near-infrared Integral Field Spectrograph (NIFS) on Gemini-North. Combining NIFS with the adaptive optics system Altair, we provide a detailed study of the core and inner structure of this PN. We focus the analysis in the prominent emission lines [Fe II] (1.6436 μm), He I (2.0585 μm), H2 (2.1214 μm), and Brγ (2.16553 μm). We find that the [Fe II] emission traces a tilted system of bipolar lobes, with the northern lobe being redshifted and the southern lobe blueshifted. The [Fe II] emission is very faint at the core and only present close to the systemic velocity. There is no H2 emission in the core, whereas the core is prominent in the He I and Brγ recombination lines. The H2 emission is concentrated in equatorial arcs of emission surrounding the core and expanding at ~30 km s-1. These arcs are compared with Hubble Space Telescope images and shown to represent nested loops belonging to the inner sections of a much larger bipolar structure that replicates the inner one. The He I and Brγ emission from the core clearly show a cylindrical central cavity that seems to represent the inner walls of an equatorial density enhancement or torus. The torus is 0.''2 wide (≡200 AU radius at a distance of 2000 pc) and expanding at <=30 km s-1. The eastern wall of the inner torus is consistently more intense than the western wall, which could indicate the presence of an off-center star, such as is observed in the similar hourglass PN, MyCn 18. A bipolar outflow is also detected in Brγ emerging within 0.''1 from the core at ~ ± 40 km s-1.

  11. Atomically detailed folding simulation of the B domain of staphylococcal protein A from random structures

    PubMed Central

    Vila, Jorge A.; Ripoll, Daniel R.; Scheraga, Harold A.

    2003-01-01

    The conformational space of the 10–55 fragment of the B-domain of staphylococcal protein A has been investigated by using the electrostatically driven Monte Carlo (EDMC) method. The ECEPP/3 (empirical conformational energy program for peptides) force-field plus two different continuum solvation models, namely SRFOPT (Solvent Radii Fixed with atomic solvation parameters OPTimized) and OONS (Ooi, Oobatake, Némethy, and Scheraga solvation model), were used to describe the conformational energy of the chain. After an exhaustive search, starting from two different random conformations, three of four runs led to native-like conformations. Boltzmann-averaged root-mean-square deviations (RMSD) for all of the backbone heavy atoms with respect to the native structure of 3.35 Å and 4.54 Å were obtained with SRFOPT and OONS, respectively. These results show that the protein-folding problem can be solved at the atomic detail level by an ab initio procedure, starting from random conformations, with no knowledge except the amino acid sequence. To our knowledge, the results reported here correspond to the largest protein ever folded from a random conformation by an initial-value formulation with a full atomic potential, without resort to knowledge-based information. PMID:14638943

  12. The Detailed Vertical Structure of Pluto's Atmosphere from the 12 Jun 2006 Stellar Occultation.

    NASA Astrophysics Data System (ADS)

    Young, Eliot F.; Buie, M. W.; French, R. G.; Olkin, C. S.; Regester, J. R.; Ruhland, C. T.; Shoemaker, K.; Young, L. A.

    2006-09-01

    On 12 JUN 2006 Pluto passed in front of a 15th magnitude star, casting a shadow across southern latitudes that included southern Australia and New Zealand, where we deployed 4 teams of observers. Pluto stellar occultations provide an opportunity to derive the bulk column abundance and the pressure, density and temperature profiles. Previous occultations were observed in 1988 and 2002 (2). We obtained a high-quality lightcurve from the 4-m AAT at a frame rate of 5 Hz, corresponding to 15 samples per scale height with a S/N of at least 25 per sample. The lightcurve contains numerous spikes that are the result of local perturbations in the vertical index of refraction profile; we resolve most of these spikes into five or more points. We expect to present changes to Pluto's bulk column abundance in the context of 1988 and 2002 events (i.e., is Pluto's atmosphere continuing to increase?) as well as high-resolution structure that derives from the detailed shape, spikes and wiggles from the separate ingress and egress portions of the occultation lightcurve. This work is supported by grants from the NSF's Major Research Instrumentation program and NASA's Planetary Astronomy program.

  13. Detailed fault structure of the 2000 Western Tottori, Japan, earthquake sequence

    USGS Publications Warehouse

    Fukuyama, E.; Ellsworth, W.L.; Waldhauser, F.; Kubo, A.

    2003-01-01

    We investigate the faulting process of the aftershock region of the 2000 western Tottori earthquake (Mw 6.6) by combining aftershock hypocenters and moment tensor solutions. Aftershock locations were precisely determined by the double difference method using P- and S-phase arrival data of the Japan Meteorological Agency unified catalog. By combining the relocated hypocenters and moment tensor solutions of aftershocks by broadband waveform inversion of FREESIA (F-net), we successfully resolved very detailed fault structures activated by the mainshock. The estimated fault model resolves 15 individual fault segments that are consistent with both aftershock distribution and focal mechanism solutions. Rupture in the mainshock was principally confined to the three fault elements in the southern half of the zone, which is also where the earliest aftershocks concentrate. With time, the northern part of the zone becomes activated, which is also reflected in the postseismic deformation field. From the stress tensor analysis of aftershock focal mechanisms, we found a rather uniform stress field in the aftershock region, although fault strikes were scattered. The maximum stress direction is N107??E, which is consistent with the tectonic stress field in this region. In the northern part of the fault, where no slip occurred during the mainshock but postseismic slip was observed, the maximum stress direction of N130??E was possible as an alternative solution of stress tensor inversion.

  14. A global/local analysis method for treating details in structural design

    NASA Technical Reports Server (NTRS)

    Aminpour, Mohammad A.; Mccleary, Susan L.; Ransom, Jonathan B.

    1993-01-01

    A method for analyzing global/local behavior of plate and shell structures is described. In this approach, a detailed finite element model of the local region is incorporated within a coarser global finite element model. The local model need not be nodally compatible (i.e., need not have a one-to-one nodal correspondence) with the global model at their common boundary; therefore, the two models may be constructed independently. The nodal incompatibility of the models is accounted for by introducing appropriate constraint conditions into the potential energy in a hybrid variational formulation. The primary advantage of this method is that the need for transition modeling between global and local models is eliminated. Eliminating transition modeling has two benefits. First, modeling efforts are reduced since tedious and complex transitioning need not be performed. Second, errors due to the mesh distortion, often unavoidable in mesh transitioning, are minimized by avoiding distorted elements beyond what is needed to represent the geometry of the component. The method is applied reduced to a plate loaded in tension and transverse bending. The plate has a central hole, and various hole sixes and shapes are studied. The method is also applied to a composite laminated fuselage panel with a crack emanating from a window in the panel. While this method is applied herein to global/local problems, it is also applicable to the coupled analysis of independently modeled components as well as adaptive refinement.

  15. Numerical prediction of oblique detonation wave structures using detailed and reduced reaction mechanisms

    NASA Astrophysics Data System (ADS)

    Thaker, A. A.; Chelliah, H. K.

    1997-12-01

    Modelling of the structure and the limiting flow turning angles of an oblique detonation wave, established by a two-dimensional wedge, requires the implementation of detailed chemical kinetic models involving a large number of chemical species. In this paper, a method of reducing the computational effort involved in simulating such high-speed reacting flows by implementing a systematically reduced reaction mechanism is presented. For a hydrogen - air mixture, starting with an elementary mechanism having eight species in 12 reactions, three alternate four-step reduced reaction mechanisms are developed by introducing the steady-state approximation for the reaction intermediates HO2, O and OH, respectively. Additional reduction of the computational effort is achieved by introducing simplifications to the thermochemical data evaluations. The influence of the numerical grid used in predicting the induction process behind the shock is also investigated. Comparisons of the induction zone predicted by two-dimensional oblique detonation wave calculations with that of a static reactor model (with initial conditions of the gas mixture specified by those behind the nonreactive oblique shock wave) are also presented. The reasonably good agreement between the three four-step reduced mechanism predictions and the starting mechanism predictions indicates that further reduction to a two-step mechanism is feasible for the physical flow time scales (corresponding to inflow Mach numbers of 8 - 10) considered here, and needs to be pursued in the future.

  16. Water replacement hypothesis in atomic detail--factors determining the structure of dehydrated bilayer stacks.

    PubMed

    Golovina, Elena A; Golovin, Andrey V; Hoekstra, Folkert A; Faller, Roland

    2009-07-22

    According to the water replacement hypothesis, trehalose stabilizes dry membranes by preventing the decrease of spacing between membrane lipids under dehydration. In this study, we use molecular-dynamics simulations to investigate the influence of trehalose on the area per lipid (APL) and related structural properties of dehydrated bilayers in atomic detail. The starting conformation of a palmitoyloleolylphosphatidylcholine lipid bilayer in excess water was been obtained by self-assembly. A series of molecular-dynamics simulations of palmitoyloleolylphosphatidylcholine with different degrees of dehydration (28.5, 11.7, and 5.4 waters per lipid) and different molar trehalose/lipid ratios (<1:1, 1:1, and >1:1) were carried out in the NPT ensemble. Water removal causes the formation of multilamellar "stacks" through periodic boundary conditions. The headgroups reorient from pointing outward to inward with dehydration. This causes changes in the electrostatic interactions between interfaces, resulting in interface interpenetration. Interpenetration creates self-spacing of the bilayers and prevents gel-phase formation. At lower concentrations, trehalose does not separate the interfaces, and acting together with self-spacing, it causes a considerable increase of APL. APL decreases at higher trehalose concentrations when the layer of sugar physically separates the interfaces. When interfaces are separated, the model confirms the water replacement hypothesis.

  17. Detailed imaging of flowing structures at depth using microseismicity: a tool for site investigation?

    NASA Astrophysics Data System (ADS)

    Pytharouli, S.; Lunn, R. J.; Shipton, Z. K.

    2011-12-01

    Field evidence shows that faults and fractures can act as focused pathways or barriers for fluid migration. This is an important property for modern engineering problems, e.g., CO2 sequestration, geological radioactive waste disposal, geothermal energy exploitation, land reclamation and remediation. For such applications the detailed characterization of the location, orientation and hydraulic properties of existing fractures is necessary. These investigations are expensive, requiring the hire of expensive equipment (excavator or drill rigs), which incur standing charges when not in use. In addition, they only provide information for discrete sample 'windows'. Non-intrusive methods have the ability to gather information across an entire area. Methods including electrical resistivity/conductivity and ground penetrating radar (GRP), have been used as tools for site investigations. Their imaging ability is often restricted due to unfavourable on-site conditions e.g. GRP is not useful in cases where a layer of clay or reinforced concrete is present. Our research has shown that high quality seismic data can be successfully used in the detailed imaging of sub-surface structures at depth; using induced microseismicity data recorded beneath the Açu reservoir in Brazil we identified orientations and values of average permeability of open shear fractures at depths up to 2.5km. Could microseismicity also provide information on the fracture width in terms of stress drops? First results from numerical simulations showed that higher stress drop values correspond to narrower fractures. These results were consistent with geological field observations. This study highlights the great potential of using microseismicity data as a supplementary tool for site investigation. Individual large-scale shear fractures in large rock volumes cannot currently be identified by any other geophysical dataset. The resolution of the method is restricted by the detection threshold of the local

  18. Indoor and soil gas radon simultaneous measurements for the purpose of detail analysis of radon entry pathways into houses.

    PubMed

    Froňka, A

    2011-05-01

    Detailed knowledge of radon transport mechanisms from the subsoil into the indoor environment is essential for the correct interpretation of results of short-term indoor radon measurements and for proper and effective design of radon mitigation systems. Radon transfer factor time variations have been studied based on simultaneous continuous indoor and soil gas radon measurements within the framework of complex radon diagnosis of individual buildings. In this context, the key influencing factors have been identified and analysed in order to provide satisfactory explanation on radon entry variations under different measurement conditions. Moreover, a new significant manner of radon entry into the indoor environment has been identified and will be discussed in detail.

  19. Accuracy assessment of modeling architectural structures and details using terrestrial laser scanning

    NASA Astrophysics Data System (ADS)

    Kedzierski, M.; Walczykowski, P.; Orych, A.; Czarnecka, P.

    2015-08-01

    One of the most important aspects when performing architectural documentation of cultural heritage structures is the accuracy of both the data and the products which are generated from these data: documentation in the form of 3D models or vector drawings. The paper describes an assessment of the accuracy of modelling data acquired using a terrestrial phase scanner in relation to the density of a point cloud representing the surface of different types of construction materials typical for cultural heritage structures. This analysis includes the impact of the scanning geometry: the incidence angle of the laser beam and the scanning distance. For the purposes of this research, a test field consisting of samples of different types of construction materials (brick, wood, plastic, plaster, a ceramic tile, sheet metal) was built. The study involved conducting measurements at different angles and from a range of distances for chosen scanning densities. Data, acquired in the form of point clouds, were then filtered and modelled. An accuracy assessment of the 3D model was conducted by fitting it with the point cloud. The reflection intensity of each type of material was also analyzed, trying to determine which construction materials have the highest reflectance coefficients, and which have the lowest reflection coefficients, and in turn how this variable changes for different scanning parameters. Additionally measurements were taken of a fragment of a building in order to compare the results obtained in laboratory conditions, with those taken in field conditions.

  20. A detailed study of nucleon structure function in nuclei in the valence quark region

    SciTech Connect

    Bianchi, N.

    1994-04-01

    The so called {open_quotes}EMC effect{close_quotes} discovered during the 1980`s, has caused a big controversy in the community of nuclear and high energy physicists; during the last ten years, five experiments have been performed in different laboratories and several hundreds of papers about the possible interpretation of the modification of the nucleon structure function inside nuclei have been published. However, from the experimental point of view, the main goal of four experiments (EMC, BCDMS, NMC, FNAL) has been to emphasize the region of low x{sub b}, where shadowing effects appear. In the region of valence quarks and nuclear effects (x{sub b} > 0.1 - 0.2) the most reliable data presently available are from the SLAC E139 experiment performed in 1983 with only 80 hours of beam time. New precise data in the valence quark region are necessary to measure separate structure functions F{sub 2}(x{sub b}, Q{sup 2}) and R{sup lt}(x{sub b},Q{sup 2}) = {sigma}{sub l}/{sigma}{sub t}, and to investigate the real A-dependence of the ratio between bound and free-nucleon structure functions which is not completely defined by the SLAC data. Moreover, from the nuclear physics point of view, a measurement on some unexplored nuclei, like {sup 3}He and {sup 48}Ca, would be of great interest. The intermediate scaling region (0.1 < x{sub b} < 0.7) would be accessible at CEBAF if the machine energy will reach 6-8 GeV, as suggested by all the tests performed on the RF cavities. This physics program has been already presented in two letter of intents.

  1. A detailed study of the structure of the nested planetary nebula, Hb 12, the Matryoshka nebula

    SciTech Connect

    Clark, D. M.; López, J. A.; Edwards, M. L.; Winge, C. E-mail: jal@astrosen.unam.mx E-mail: cwinge@gemini.edu

    2014-11-01

    We present near-IR, integral field spectroscopic observations of the planetary nebula (PN) Hb 12 using Near-infrared Integral Field Spectrograph (NIFS) on Gemini-North. Combining NIFS with the adaptive optics system Altair, we provide a detailed study of the core and inner structure of this PN. We focus the analysis in the prominent emission lines [Fe II] (1.6436 μm), He I (2.0585 μm), H{sub 2} (2.1214 μm), and Br{sub γ} (2.16553 μm). We find that the [Fe II] emission traces a tilted system of bipolar lobes, with the northern lobe being redshifted and the southern lobe blueshifted. The [Fe II] emission is very faint at the core and only present close to the systemic velocity. There is no H{sub 2} emission in the core, whereas the core is prominent in the He I and Br{sub γ} recombination lines. The H{sub 2} emission is concentrated in equatorial arcs of emission surrounding the core and expanding at ∼30 km s{sup –1}. These arcs are compared with Hubble Space Telescope images and shown to represent nested loops belonging to the inner sections of a much larger bipolar structure that replicates the inner one. The He I and Br{sub γ} emission from the core clearly show a cylindrical central cavity that seems to represent the inner walls of an equatorial density enhancement or torus. The torus is 0.''2 wide (≡200 AU radius at a distance of 2000 pc) and expanding at ≤30 km s{sup –1}. The eastern wall of the inner torus is consistently more intense than the western wall, which could indicate the presence of an off-center star, such as is observed in the similar hourglass PN, MyCn 18. A bipolar outflow is also detected in Br{sub γ} emerging within 0.''1 from the core at ∼ ± 40 km s{sup –1}.

  2. UNVEILING THE DETAILED DENSITY AND VELOCITY STRUCTURES OF THE PROTOSTELLAR CORE B335

    SciTech Connect

    Kurono, Yasutaka; Saito, Masao; Kamazaki, Takeshi; Morita, Koh-Ichiro; Kawabe, Ryohei

    2013-03-10

    We present an observational study of the protostellar core B335 harboring a low-mass Class 0 source. The observations of the H{sup 13}CO{sup +}(J = 1-0) line emission were carried out using the Nobeyama 45 m telescope and Nobeyama Millimeter Array. Our combined image of the interferometer and single-dish data depicts detailed structures of the dense envelope within the core. We found that the core has a radial density profile of n(r){proportional_to}r {sup -p} and a reliable difference in the power-law indices between the outer and inner regions of the core: p Almost-Equal-To 2 for r {approx}> 4000 AU and p Almost-Equal-To 1.5 for r {approx}< 4000 AU. The dense core shows a slight overall velocity gradient of {approx}1.0 km s{sup -1} over the scale of 20, 000 AU across the outflow axis. We believe that this velocity gradient represents a solid-body-like rotation of the core. The dense envelope has a quite symmetrical velocity structure with a remarkable line broadening toward the core center, which is especially prominent in the position-velocity diagram across the outflow axis. The model calculations of position-velocity diagrams do a good job of reproducing observational results using the collapse model of an isothermal sphere in which the core has an inner free-fall region and an outer region conserving the conditions at the formation stage of a central stellar object. We derived a central stellar mass of {approx}0.1 M{sub Sun }, and suggest a small inward velocity, v{sub r{>=}r{sub i{sub n{sub f}}}}{approx}0 km s{sup -1} in the outer core at {approx}> 4000 AU. We concluded that our data can be well explained by gravitational collapse with a quasi-static initial condition, such as Shu's model, or by the isothermal collapse of a marginally critical Bonnor-Ebert sphere.

  3. Toward a detailed understanding of search trajectories in fragment assembly approaches to protein structure prediction

    PubMed Central

    Handl, Julia; Lovell, Simon C.

    2016-01-01

    ABSTRACT Energy functions, fragment libraries, and search methods constitute three key components of fragment‐assembly methods for protein structure prediction, which are all crucial for their ability to generate high‐accuracy predictions. All of these components are tightly coupled; efficient searching becomes more important as the quality of fragment libraries decreases. Given these relationships, there is currently a poor understanding of the strengths and weaknesses of the sampling approaches currently used in fragment‐assembly techniques. Here, we determine how the performance of search techniques can be assessed in a meaningful manner, given the above problems. We describe a set of techniques that aim to reduce the impact of the energy function, and assess exploration in view of the search space defined by a given fragment library. We illustrate our approach using Rosetta and EdaFold, and show how certain features of these methods encourage or limit conformational exploration. We demonstrate that individual trajectories of Rosetta are susceptible to local minima in the energy landscape, and that this can be linked to non‐uniform sampling across the protein chain. We show that EdaFold's novel approach can help balance broad exploration with locating good low‐energy conformations. This occurs through two mechanisms which cannot be readily differentiated using standard performance measures: exclusion of false minima, followed by an increasingly focused search in low‐energy regions of conformational space. Measures such as ours can be helpful in characterizing new fragment‐based methods in terms of the quality of conformational exploration realized. Proteins 2016; 84:411–426. © 2016 The Authors Proteins: Structure, Function, and Bioinformatics Published by Wiley Periodicals, Inc. PMID:26799916

  4. Detailed plasma potential measurements in a radio-frequency expanding plasma obtained from various electrostatic probes

    SciTech Connect

    Lafleur, T.; Charles, C.; Boswell, R. W.

    2009-04-15

    On-axis plasma potential measurements have been made with an emissive probe in a low pressure (0.044 Pa) rf expanding plasma containing an ion beam. The beam is detected with a retarding field energy analyzer (RFEA), and is seen to disappear at high pressure (0.39 Pa). The emissive probe measurements are in very good agreement with corresponding measurements made with two separate RFEAs, and the results indicate that the floating potential of the strongly emitting probe gives an accurate measure of the plasma potential under the present conditions.

  5. Toward a detailed understanding of search trajectories in fragment assembly approaches to protein structure prediction.

    PubMed

    Kandathil, Shaun M; Handl, Julia; Lovell, Simon C

    2016-04-01

    Energy functions, fragment libraries, and search methods constitute three key components of fragment-assembly methods for protein structure prediction, which are all crucial for their ability to generate high-accuracy predictions. All of these components are tightly coupled; efficient searching becomes more important as the quality of fragment libraries decreases. Given these relationships, there is currently a poor understanding of the strengths and weaknesses of the sampling approaches currently used in fragment-assembly techniques. Here, we determine how the performance of search techniques can be assessed in a meaningful manner, given the above problems. We describe a set of techniques that aim to reduce the impact of the energy function, and assess exploration in view of the search space defined by a given fragment library. We illustrate our approach using Rosetta and EdaFold, and show how certain features of these methods encourage or limit conformational exploration. We demonstrate that individual trajectories of Rosetta are susceptible to local minima in the energy landscape, and that this can be linked to non-uniform sampling across the protein chain. We show that EdaFold's novel approach can help balance broad exploration with locating good low-energy conformations. This occurs through two mechanisms which cannot be readily differentiated using standard performance measures: exclusion of false minima, followed by an increasingly focused search in low-energy regions of conformational space. Measures such as ours can be helpful in characterizing new fragment-based methods in terms of the quality of conformational exploration realized.

  6. A Detailed Derivation of Gaussian Orbital-Based Matrix Elements in Electron Structure Calculations

    ERIC Educational Resources Information Center

    Petersson, T.; Hellsing, B.

    2010-01-01

    A detailed derivation of analytic solutions is presented for overlap, kinetic, nuclear attraction and electron repulsion integrals involving Cartesian Gaussian-type orbitals. It is demonstrated how s-type orbitals can be used to evaluate integrals with higher angular momentum via the properties of Hermite polynomials and differentiation with…

  7. A Detailed Derivation of Gaussian Orbital-Based Matrix Elements in Electron Structure Calculations

    ERIC Educational Resources Information Center

    Petersson, T.; Hellsing, B.

    2010-01-01

    A detailed derivation of analytic solutions is presented for overlap, kinetic, nuclear attraction and electron repulsion integrals involving Cartesian Gaussian-type orbitals. It is demonstrated how s-type orbitals can be used to evaluate integrals with higher angular momentum via the properties of Hermite polynomials and differentiation with…

  8. Technique for direct measurement of thermal conductivity of elastomers and a detailed uncertainty analysis

    NASA Astrophysics Data System (ADS)

    Ralphs, Matthew I.; Smith, Barton L.; Roberts, Nicholas A.

    2016-11-01

    High thermal conductivity thermal interface materials (TIMs) are needed to extend the life and performance of electronic circuits. A stepped bar apparatus system has been shown to work well for thermal resistance measurements with rigid materials, but most TIMs are elastic. This work studies the uncertainty of using a stepped bar apparatus to measure the thermal resistance and a tensile/compression testing machine to estimate the compressed thickness of polydimethylsiloxane for a measurement on the thermal conductivity, k eff. An a priori, zeroth order analysis is used to estimate the random uncertainty from the instrumentation; a first order analysis is used to estimate the statistical variation in samples; and an a posteriori, Nth order analysis is used to provide an overall uncertainty on k eff for this measurement method. Bias uncertainty in the thermocouples is found to be the largest single source of uncertainty. The a posteriori uncertainty of the proposed method is 6.5% relative uncertainty (68% confidence), but could be reduced through calibration and correlated biases in the temperature measurements.

  9. Technical notes: A detailed study for the provision of measurement uncertainty and traceability for goniospectrometers

    NASA Astrophysics Data System (ADS)

    Peltoniemi, Jouni I.; Hakala, Teemu; Suomalainen, Juha; Honkavaara, Eija; Markelin, Lauri; Gritsevich, Maria; Eskelinen, Juho; Jaanson, Priit; Ikonen, Erkki

    2014-10-01

    The measurement uncertainty and traceability of the Finnish Geodetic Institutess field gonio-spectro-polarimeter FIGIFIGO have been assessed. First, the reference standard (Spectralon sample) was measured at the National Standard Laboratory of MIKES-Aalto. This standard was transferred to FGIs field reference standard (larger Spectralon sample), and from that to the unmanned aerial vehicle (UAV), reference standards (1 m2 plates). The reflectance measurement uncertainty of FIGIFIGO has been estimated to be 0.01 in ideal laboratory conditions, but about 0.02-0.05 in typical field conditions, larger at larger solar or observation zenith angles. Target specific uncertainties can increase total uncertainty even to 0.1-0.2. The angular reading uncertainty is between 1° and 3°, depending on user selection, and the polarisation uncertainty is around 0.01. For UAV, the transferred reflectance uncertainty is about 0.05-0.1, depending on, how ideal the measurement conditions are. The design concept of FIGIFIGO has been proved to have a number of advantages, such as a well-adopted user-friendly interface, a high level of automation and excellent suitability for the field measurements. It is a perfect instrument for collection of reference data on a given target in natural (and well-recorded) conditions. In addition to the strong points of FIGIFIGO, the current study reveals several issues that need further attention, such as the field of view, illumination quality, polarisation calibration, Spectralon reflectance and polarisation properties in the 1000-2400 nm range.

  10. Solution Synchrotron X-ray Diffraction Reveals Structural Details of Lipid Domains in Ternary Mixtures

    SciTech Connect

    Yuan, J.; Kiss, A; Pramudya, Y; Nguyen, L; Hirst, L

    2009-01-01

    The influence of cholesterol on lipid bilayer structure is significant and the effect of cholesterol on lipid sorting and phase separation in lipid-raft-forming model membrane systems has been well investigated by microscopy methods on giant vesicles. An important consideration however is the influence of fluorescence illumination on the phase state of these lipids and this effect must be carefully minimized. In this paper, we show that synchrotron x-ray scattering on solution lipid mixtures is an effective alternative technique for the identification and characterization of the l o (liquid ordered) and l d (liquid disordered) phases. The high intensity of synchrotron x rays allows the observation of up to 5 orders of diffraction from the l o phase, whereas only two are clearly visible when the l d phase alone is present. This data can be collected in approximately 1 min/sample, allowing rapid generation of phase data. In this paper, we measure the lamellar spacing in both the liquid-ordered and liquid-disordered phases simultaneously, as a function of cholesterol concentration in two different ternary mixtures. We also observe evidence of a third gel-phaselike population at 10-12 mol % cholesterol and determine the thickness of the bilayer for this phase. Importantly we are able to look at phase coexistence in the membrane independent of photoeffects.

  11. DETAILED MEASUREMENTS OF THE ELECTRON CYCLOTRON CURRENT DRIVE EFFICIENCY ON DIIID

    SciTech Connect

    PETTY, C.C.; PRATER, R.; LOHR, J.; LUCE, T.C.; FOX,W.R.; HARVEY, R.W.; KINSEY, J.E.; LAO, L.L.; MAKOWSKI, M.A.

    2002-05-01

    Electron cyclotron current drive (ECCD) experiments on the DIII-D tokamak are solidifying the physics basis for localized, off-axis current drive, the goal being to validate a predictive model for ECCD. The ECCD profiles are determined from the magnetic field pitch angles measured by motional Stark effect (MSE) polarimetry. The measured ECCD switches from the co to the counter direction as the toroidal injection angle is varied with a profile width that is in accordance with ray tracing calculations. Tests of electron trapping in low beta plasmas show that the ECCD efficiency decreases rapidly as the deposition is moved off-axis and towards the outboard side of the plasma, but the detrimental effects of electron trapping on the current drive are greatly reduced in high beta plasmas. Overall, the measured ECCD is in good agreement with theoretical calculations using a quasilinear Fokker-Planck code over a wide range of injection angles and plasma parameters.

  12. Obtaining detailed structural information about supramolecular systems on surfaces by combining high-resolution force microscopy with ab initio calculations.

    PubMed

    Kawai, Shigeki; Sadeghi, Ali; Xu, Feng; Feng, Xu; Peng, Lifen; Lifen, Peng; Pawlak, Rémy; Glatzel, Thilo; Willand, Alexander; Orita, Akihiro; Otera, Junzo; Goedecker, Stefan; Meyer, Ernst

    2013-10-22

    State-of-the art experimental techniques such as scanning tunneling microscopy have great difficulties in extracting detailed structural information about molecules adsorbed on surfaces. By combining atomic force microscopy and Kelvin probe force microscopy with ab initio calculations, we demonstrate that we can obtain a wealth of detailed structural information about the molecule itself and its environment. Studying an FFPB molecule on a gold surface, we are able to determine its exact location on the surface, the nature of its bonding properties with neighboring molecules that lead to the growth of one-dimensional strips, and the internal torsions and bendings of the molecule.

  13. Measuring Structural Gender Equality in Mexico: A State Level Analysis

    ERIC Educational Resources Information Center

    Frias, Sonia M.

    2008-01-01

    The main goal of this article is to assess the level of gender equality across the 32 Mexican states. After reviewing conceptual and methodological issues related to previous measures of structural inequality I detail the logic and methodology involved in the construction of a composite and multidimensional measure of gender equality, at the…

  14. Measuring Structural Gender Equality in Mexico: A State Level Analysis

    ERIC Educational Resources Information Center

    Frias, Sonia M.

    2008-01-01

    The main goal of this article is to assess the level of gender equality across the 32 Mexican states. After reviewing conceptual and methodological issues related to previous measures of structural inequality I detail the logic and methodology involved in the construction of a composite and multidimensional measure of gender equality, at the…

  15. In situ spatiotemporal measurements of the detailed azimuthal substructure of the substorm current wedge

    PubMed Central

    Forsyth, C; Fazakerley, A N; Rae, I J; J Watt, C E; Murphy, K; Wild, J A; Karlsson, T; Mutel, R; Owen, C J; Ergun, R; Masson, A; Berthomier, M; Donovan, E; Frey, H U; Matzka, J; Stolle, C; Zhang, Y

    2014-01-01

    The substorm current wedge (SCW) is a fundamental component of geomagnetic substorms. Models tend to describe the SCW as a simple line current flowing into the ionosphere toward dawn and out of the ionosphere toward dusk, linked by a westward electrojet. We use multispacecraft observations from perigee passes of the Cluster 1 and 4 spacecraft during a substorm on 15 January 2010, in conjunction with ground-based observations, to examine the spatial structuring and temporal variability of the SCW. At this time, the spacecraft traveled east-west azimuthally above the auroral region. We show that the SCW has significant azimuthal substructure on scales of 100 km at altitudes of 4000–7000 km. We identify 26 individual current sheets in the Cluster 4 data and 34 individual current sheets in the Cluster 1 data, with Cluster 1 passing through the SCW 120–240 s after Cluster 4 at 1300–2000 km higher altitude. Both spacecraft observed large-scale regions of net upward and downward field-aligned current, consistent with the large-scale characteristics of the SCW, although sheets of oppositely directed currents were observed within both regions. We show that the majority of these current sheets were closely aligned to a north-south direction, in contrast to the expected east-west orientation of the preonset aurora. Comparing our results with observations of the field-aligned current associated with bursty bulk flows (BBFs), we conclude that significant questions remain for the explanation of SCW structuring by BBF-driven “wedgelets.” Our results therefore represent constraints on future modeling and theoretical frameworks on the generation of the SCW. Key Points The substorm current wedge (SCW) has significant azimuthal structure Current sheets within the SCW are north-south aligned The substructure of the SCW raises questions for the proposed wedgelet scenario PMID:26167439

  16. Detailed Anatomical Orientations for Certain Types of Morphometric Measurements Can Be Determined Automatically With Geometric Algorithms.

    PubMed

    Boyer, Doug M; Winchester, Julia M; Glynn, Chris; Puente, Jesus

    2015-11-01

    Morphometric datasets only convey useful information about variation when measurement landmarks and relevant anatomical axes are clearly defined. We propose that anatomical axes of 3D digital models of bones can be standardized prior to measurement using an algorithm that automatically finds a universal geometric alignment among sampled bones. As a case study, we use teeth of "prosimian" primates. In this sample, equivalent occlusal planes are determined automatically using the R-package auto3dgm. The area of projection into the occlusal plane for each tooth is the measurement of interest. This area is used in computation of a shape metric called relief index (RFI), the natural log of the square root of crown area divided by the square root of occlusal plane projection area. We compare mean and variance parameters of area and RFI values computed from these automatically orientated tooth models with values computed from manually orientated tooth models. According to our results, the manual and automated approaches yield extremely similar mean and variance parameters. The only differences that plausibly modify interpretations of biological meaning slightly favor the automated treatment because a greater proportion of differences among subsamples in the automated treatment are correlated with dietary differences. We conclude that-at least for dental topographic metrics-automated alignment recovers a variance pattern that has meaning similar to previously published datasets based on manual data collection. Therefore, future applications of dental topography can take advantage of automatic alignment to increase objectivity and repeatability.

  17. Detailed flow and force measurements in a rotated triangular tube bundle subjected to two-phase cross-flow

    NASA Astrophysics Data System (ADS)

    Pettigrew, M. J.; Zhang, C.; Mureithi, N. W.; Pamfil, D.

    2005-05-01

    Two-phase cross-flow exists in many shell-and-tube heat exchangers. A detailed knowledge of the characteristics of two-phase cross-flow in tube bundles is required to understand and formulate flow-induced vibration parameters such as damping, fluidelastic instability, and random excitation due to turbulence. An experimental program was undertaken with a rotated-triangular array of cylinders subjected to air/water flow to simulate two-phase mixtures. The array is made of relatively large diameter cylinders (38 mm) to allow for detailed two-phase flow measurements between cylinders. Fiber-optic probes were developed to measure local void fraction. Local flow velocities and bubble diameters or characteristic lengths of the two-phase mixture are obtained by using double probes. Both the dynamic lift and drag forces were measured with a strain gauge instrumented cylinder.

  18. Measurements of Alpha-dicarbonyl Compounds: A Detailed Instrument Intercomparison at the European Photoreactor (EUPHORE)

    NASA Astrophysics Data System (ADS)

    Baeza Romero, M.; Rickard, A.; Peppe, S.; Muñoz, A.; Ball, S.; Ródenas, M.; Sánchez, P.; Daniels, M.; Volkamer, R.; Thalman, R.; Keutsch, F.; Henry, S.; Monks, P.; Goodall, I.; Borrás, E.; Vázquez, M.

    2012-04-01

    The α-dicarbonyl compounds glyoxal (GLY, CH(O)CHO) and methylglyoxal (MGLY, CH3C(O)CHO)) are ubiquitous intermediates formed in the photooxidation of a wide range of anthropogenic and biogenic volatile organic compounds (VOCs). Recent measurements demonstrate that large uncertainties exist in the amount of glyoxal formed from isoprene photooxidation, the dominant VOC emitted into the atmosphere (1, 2). In addition, α-dicarbonyls are known to be precursors of secondary organic aerosol (SOA) and can potentially form a significant fraction of the missing global SOA in atmospheric models (3, 4). However, the exact role of such compounds is still not well established. One of the main reasons for such uncertainties is the difficulty in measuring them, as they are very reactive and difficult to handle experimentally. In order to elucidate both the chemical and instrumental issues related to the quantitative measurement of these compounds, a short experimental chamber campaign was carried out in the EUPHORE photo-reactor in Valencia, Spain to compare a number of currently available techniques (both optical and spectrometric). The campaign comprised a set of experiments simulating typical urban and semi-rural conditions. Measurements were performed over a range of concentrations in order to investigate the impacts of the presence of potential interferants in the gas mixtures sampled from the chamber (i.e. aerosol, NOx, short chain carbonyls and ozone). The gas and aerosol phase compositional evolution was monitored simultaneously. Different amounts of GLY and/or MGLY were added directly to the chamber or were generated in-situ from the oxidation of various VOC precursors. The following instrumental techniques were employed during the campaign: (Blue) LED-CE-DOAS (cavity enhanced differential optical absorption spectroscopy), long-path DOAS, SPME (solid phase micro extraction) -GC/MS, Fourier Transform Infrared (FTIR) spectroscopy, GC-ECD (electron capture detection

  19. In situ spatiotemporal measurements of the detailed azimuthal substructure of the substorm current wedge.

    PubMed

    Forsyth, C; Fazakerley, A N; Rae, I J; J Watt, C E; Murphy, K; Wild, J A; Karlsson, T; Mutel, R; Owen, C J; Ergun, R; Masson, A; Berthomier, M; Donovan, E; Frey, H U; Matzka, J; Stolle, C; Zhang, Y

    2014-02-01

    The substorm current wedge (SCW) is a fundamental component of geomagnetic substorms. Models tend to describe the SCW as a simple line current flowing into the ionosphere toward dawn and out of the ionosphere toward dusk, linked by a westward electrojet. We use multispacecraft observations from perigee passes of the Cluster 1 and 4 spacecraft during a substorm on 15 January 2010, in conjunction with ground-based observations, to examine the spatial structuring and temporal variability of the SCW. At this time, the spacecraft traveled east-west azimuthally above the auroral region. We show that the SCW has significant azimuthal substructure on scales of 100 km at altitudes of 4000-7000 km. We identify 26 individual current sheets in the Cluster 4 data and 34 individual current sheets in the Cluster 1 data, with Cluster 1 passing through the SCW 120-240 s after Cluster 4 at 1300-2000 km higher altitude. Both spacecraft observed large-scale regions of net upward and downward field-aligned current, consistent with the large-scale characteristics of the SCW, although sheets of oppositely directed currents were observed within both regions. We show that the majority of these current sheets were closely aligned to a north-south direction, in contrast to the expected east-west orientation of the preonset aurora. Comparing our results with observations of the field-aligned current associated with bursty bulk flows (BBFs), we conclude that significant questions remain for the explanation of SCW structuring by BBF-driven "wedgelets." Our results therefore represent constraints on future modeling and theoretical frameworks on the generation of the SCW.

  20. Design details of Intelligent Instruments for PLC-free Cryogenic measurements, control and data acquisition

    NASA Astrophysics Data System (ADS)

    Antony, Joby; Mathuria, D. S.; Chaudhary, Anup; Datta, T. S.; Maity, T.

    2017-02-01

    Cryogenic network for linear accelerator operations demand a large number of Cryogenic sensors, associated instruments and other control-instrumentation to measure, monitor and control different cryogenic parameters remotely. Here we describe an alternate approach of six types of newly designed integrated intelligent cryogenic instruments called device-servers which has the complete circuitry for various sensor-front-end analog instrumentation and the common digital back-end http-server built together, to make crateless PLC-free model of controls and data acquisition. These identified instruments each sensor-specific viz. LHe server, LN2 Server, Control output server, Pressure server, Vacuum server and Temperature server are completely deployed over LAN for the cryogenic operations of IUAC linac (Inter University Accelerator Centre linear Accelerator), New Delhi. This indigenous design gives certain salient features like global connectivity, low cost due to crateless model, easy signal processing due to integrated design, less cabling and device-interconnectivity etc.

  1. Detailed simulation of structural color generation inspired by the Morpho butterfly.

    PubMed

    Steindorfer, Michael A; Schmidt, Volker; Belegratis, Maria; Stadlober, Barbara; Krenn, Joachim R

    2012-09-10

    The brilliancy and variety of structural colors found in nature has become a major scientific topic in recent years. Rapid-prototyping processes enable the fabrication of according structures, but the technical exploitation requires a profound understanding of structural features and material properties regarding the generation of reflected color. This paper presents an extensive simulation of the reflectance spectra of a simplified 2D Morpho butterfly wing model by utilizing the finite-difference time-domain method. The structural parameters are optimized for reflection in a given spectral range. A comparison to simpler models, such as a plane dielectric layer stack, provides an understanding of the origin of the reflection behavior. We find that the wavelength of the reflection maximum is mainly set by the lateral dimensions of the structures. Furthermore small variations of the vertical dimensions leave the spectral position of the reflectance wavelength unchanged, potentially reducing grating effects.

  2. Terrestrial bodies orbiter, LUNAR - A system for detailed global measurements of a planet's properties

    NASA Technical Reports Server (NTRS)

    Burke, J. D.

    1976-01-01

    The NASA Lunar Polar Orbiter, to be launched by a Delta vehicle in 1980, is designed to perform a global exploration of such moon properties as the gravity field, figure, and surface composition, as well as a lunar resource survey. The paper reviews the mission, spacecraft, and data system concepts in terms of baseline mission sequence, choice of orbits, spacecraft configuration requirements, mission sequence requirements and data system and operations. Scientific experiments planned for the Orbiter mission include geophysical altimetry and gravity experiments, heat flow experiment, magnetic field experiments, measurements of the moon's natural gamma-ray spectrum, X-ray fluorescence of lunar surface materials, sunlight reflectance spectroscopy, and spectro-stereo imaging. Characteristics of instruments designed for use in these investigations are examined. Through the use of advanced sensors and data-system techniques, coupled with well-developed spacecraft systems, the mission promises to return a very large quantity and variety of lunar data at a cost comparable with that of simpler missions in the past.

  3. Measure of the violation of the detailed balance criterion: A possible definition of a ``distance'' from equilibrium

    NASA Astrophysics Data System (ADS)

    Platini, T.

    2011-01-01

    Motivated by the classification of nonequilibrium steady states suggested by R. K. P. Zia and B. Schmittmann, in J. Stat. Mech.1742-546810.1088/1742-5468/2007/07/P07012 (2007) P07012, we propose to measure the violation of the detailed balance criterion by the p norm (||K*||p) of the matrix formed by the probability currents. Its asymptotic analysis, for the totally asymmetric simple exclusion process, motivates the definition of a “distance” from equilibrium K* obtained for p=1. In addition, we show that the latter quantity and the average activity are both related to the probability distribution of the entropy production. Finally, considering the open asymmetric simple exclusion process and open zero-range process, we show that the current of particles gives an exact measure of the violation of detailed balance.

  4. Structural biologists capture detailed image of gene regulator’s fleeting form | Center for Cancer Research

    Cancer.gov

    Using an ultrafast, high-intensity radiation source called an X-ray free-electron laser (XFEL), scientists have captured an atomic-level picture of an RNA structure called a riboswitch as it reorganizes itself to regulate protein production. The structure they visualized has never before been seen, and likely exists for only milliseconds after the riboswitch first encounters its activating molecule.  Read more...  

  5. Detailed Studies on the Structure and Dynamics of Reacting Dusty Flows at Normal and Microgravity

    NASA Technical Reports Server (NTRS)

    Egolfopoulos, Fokion N.; Campbell, Charles S.

    1997-01-01

    Two-phase reacting flows are substantially less understood compared to gas phase flows. While extensive work has been done on sprays, less attention has been given to the details of dusty reacting flows. Dusty flows are of particular interest for a wide range of applications. Particles can be present in a gas intentionally or unintentionally, and they can be inert or reacting. Inert particles can be also present in an otherwise reacting gas flow, and that can lead to flame cooling and modification of the extinction limits of a combustible mixture. Reacting solid particles can release substantial amounts of heat upon oxidation, and can be used either for propulsion (e.g. Al, B, Mg) or power generation (coal). Furthermore, accidents can occur when a reacting dust accumulates in air and which, in the presence of an ignition source, can cause explosion. Such explosions can occur during lumber milling, in grain elevators, and in mine galleries.

  6. Assembly dynamics and detailed structure of 1-propanethiol monolayers on Au(111) surfaces observed real time by in situ STM.

    PubMed

    Zhang, Jingdong; Chi, Qijin; Ulstrup, Jens

    2006-07-04

    1-Propanethiol is chosen as a model alkanethiol to probe detailed mechanisms of the self-assembled monolayer (SAM) formation at aqueous/Au(111) interfaces. The assembly processes, including initial physi- and chemisorption, pit formation, and domain growth, were recorded into movies in real-time with high resolution by in situ scanning tunneling microscopy (STM) under potential control. Two major adsorption steps were disclosed in the propanethiol SAM formation. The first step involves weak interactions accompanied by the lift of the Au(111) surface reconstruction, which depends reversibly on the electrochemical potentials. The second step is chemisorption to form a dense monolayer, accompanied by formation of pits as well as structural changes in the terrace edges. Pits emerged at the stage of the reconstruction lift and increased to a maximum surface coverage of 4.0 +/- 0.4% at the completion of the SAM formation. Well-defined triangular pits in the SAM were found on the large terraces (more than 300 nm wide), whereas few and small pinholes appeared at the terrace edge areas. Smooth edges were converted into saw-like structural features during the SAM formation, primarily along the Au(111) atomic rows. These observations suggest that shrinking and rearrangement of gold atoms are responsible for both formation of the pits and the shape changes of the terrace edges. STM images disclose a (2 square root 3 x 3)R30 degrees periodic lattice within the ordered domains. Along with electrochemical measurements, each lattice unit is assigned to contain four propanethiol molecules exhibiting different electronic contrasts, which might originate in different surface orientations of the adsorbed molecules.

  7. Mechanistic Details of Glutathione Biosynthesis Revealed by Crystal Structures of Saccharomyces cerevisiae Glutamate Cysteine Ligase

    SciTech Connect

    Biterova, Ekaterina I.; Barycki, Joseph J.

    2009-12-01

    Glutathione is a thiol-disulfide exchange peptide critical for buffering oxidative or chemical stress, and an essential cofactor in several biosynthesis and detoxification pathways. The rate-limiting step in its de novo biosynthesis is catalyzed by glutamate cysteine ligase, a broadly expressed enzyme for which limited structural information is available in higher eukaryotic species. Structural data are critical to the understanding of clinical glutathione deficiency, as well as rational design of enzyme modulators that could impact human disease progression. Here, we have determined the structures of Saccharomyces cerevisiae glutamate cysteine ligase (ScGCL) in the presence of glutamate and MgCl{sub 2} (2.1 {angstrom}; R = 18.2%, R{sub free} = 21.9%), and in complex with glutamate, MgCl{sub 2}, and ADP (2.7 {angstrom}; R = 19.0%, R{sub free} = 24.2%). Inspection of these structures reveals an unusual binding pocket for the {alpha}-carboxylate of the glutamate substrate and an ATP-independent Mg{sup 2+} coordination site, clarifying the Mg{sup 2+} dependence of the enzymatic reaction. The ScGCL structures were further used to generate a credible homology model of the catalytic subunit of human glutamate cysteine ligase (hGCLC). Examination of the hGCLC model suggests that post-translational modifications of cysteine residues may be involved in the regulation of enzymatic activity, and elucidates the molecular basis of glutathione deficiency associated with patient hGCLC mutations.

  8. Detailed Study of the TE band structure of two dimensional metallic photonic crystals with square symmetry

    NASA Astrophysics Data System (ADS)

    Sedghi, Aliasghar; Valiaghaie, Soma; Soufiani, Ahad Rounaghi

    2014-10-01

    By virtue of the efficiency of the Dirichlet-to-Neumann map method, we have calculated, for H-polarization (TE mode), the band structure of 2D photonic crystals with a square lattice composed of metallic rods embedded in an air background. The rod in the unit cell is chosen to be circular in shape. Here, from a practical point of view, in order to obtain maximum band gaps, we have studied the band structure as a function of the size of the rods. We have also studied the flat bands appearing in the band structures and have shown that for frequencies around the surface plasmon frequency, the modes are highly localized at the interface between the metallic rods and the air background.

  9. Detailed pressure distribution measurements obtained on several configurations of an aspect-ratio-7 variable twist wing

    NASA Technical Reports Server (NTRS)

    Holbrook, G. T.; Dunham, D. M.

    1985-01-01

    Detailed pressure distribution measurements were made for 11 twist configurations of a unique, multisegmented wing model having an aspect ratio of 7 and a taper ratio of 1. These configurations encompassed span loads ranging from that of an untwisted wing to simple flapped wings both with and without upper-surface spoilers attached. For each of the wing twist configurations, electronic scanning pressure transducers were used to obtain 580 surface pressure measurements over the wing in about 0.1 sec. Integrated pressure distribution measurements compared favorably with force-balance measurements of lift on the model when the model centerbody lift was included. Complete plots and tabulations of the pressure distribution data for each wing twist configuration are provided.

  10. Detailed Study of Emission Structures in the Vicinity of LkHα 198

    NASA Astrophysics Data System (ADS)

    Gevorgyan, M. H.; Movsessian, T. A.; Andreasyan, H. R.; Magakian, T. Yu.

    2016-09-01

    Results from a study of collimated flows near the star LkHα 198 are reported. Observations were made using the VAGR multipupil spectrograph installed on the 2.6-m telescope at the Byurakan Astrophysical Observatory. The morphology and kinematics of emission structures in the vicinity of LkHα 198, including HH 161, were studied and electron density charts obtained. Besides the HH 161 object, our data revealed an arc-shaped emission structure with LkHα 198 at its apex. A shape of this kind is usually a direct indication of the presence of a cavity in a dark cloud blown out by a directed outflow. In addition, a faint "tail" extending in the direction of the central star is observed in HH 161. A comparison of these results with radio frequency observations shows that the probable source of HH 161 is the binary system LkHα 198.

  11. The effects of design details on cost and weight of fuselage structures

    NASA Technical Reports Server (NTRS)

    Swanson, G. D.; Metschan, S. L.; Morris, M. R.; Kassapoglou, C.

    1993-01-01

    Crown panel design studies showing the relationship between panel size, cost, weight, and aircraft configuration are compared to aluminum design configurations. The effects of a stiffened sandwich design concept are also discussed. This paper summarizes the effect of a design cost model in assessing the cost and weight relationships for fuselage crown panel designs. Studies were performed using data from existing aircraft to assess the effects of different design variables on the cost and weight of transport fuselage crown panel design. Results show a strong influence of load levels, panel size, and material choices on the cost and weight of specific designs. A design tool being developed under the NASA ACT program is used in the study to assess these issues. The effects of panel configuration comparing postbuckled and buckle resistant stiffened laminated structure is compared to a stiffened sandwich concept. Results suggest some potential economy with stiffened sandwich designs for compression dominated structure with relatively high load levels.

  12. A detailed view of a ribosomal active site: the structure of the L11-RNA complex.

    PubMed

    Wimberly, B T; Guymon, R; McCutcheon, J P; White, S W; Ramakrishnan, V

    1999-05-14

    We report the crystal structure of a 58 nucleotide fragment of 23S ribosomal RNA bound to ribosomal protein L11. This highly conserved ribonucleoprotein domain is the target for the thiostrepton family of antibiotics that disrupt elongation factor function. The highly compact RNA has both familiar and novel structural motifs. While the C-terminal domain of L11 binds RNA tightly, the N-terminal domain makes only limited contacts with RNA and is proposed to function as a switch that reversibly associates with an adjacent region of RNA. The sites of mutations conferring resistance to thiostrepton and micrococcin line a narrow cleft between the RNA and the N-terminal domain. These antibiotics are proposed to bind in this cleft, locking the putative switch and interfering with the function of elongation factors.

  13. The detailed spatial structure of field-aligned currents comprising the substorm current wedge

    NASA Astrophysics Data System (ADS)

    Murphy, Kyle R.; Mann, Ian R.; Rae, I. Jonathan; Waters, Colin L.; Frey, Harald U.; Kale, Andy; Singer, Howard J.; Anderson, Brian J.; Korth, Haje

    2013-12-01

    We present a comprehensive two-dimensional view of the field-aligned currents (FACs) during the late growth and expansion phases for three isolated substorms utilizing in situ observations from the Active Magnetosphere and Planetary Electrodynamics Response Experiment and from ground-based magnetometer and optical instrumentation from the Canadian Array for Realtime Investigations of Magnetic Activity and Time History of Events and Macroscale Interactions during Substorms ground-based arrays. We demonstrate that the structure of FACs formed during the expansion phase and associated with the substorm current wedge is significantly more complex than a simple equivalent line current model comprising a downward FAC in the east and upward FAC in the west. This two-dimensional view demonstrates that azimuthal bands of upward and downward FACs with periodic structuring in latitude form across midnight and can span up to 8 h of magnetic local time. However, when averaged over latitude, the overall longitudinal structure of the net FACs resembles the simpler equivalent line current description of the substorm current wedge (SCW). In addition, we demonstrate that the upward FAC elements of the structured SCW are spatially very well correlated with discrete aurora during the substorm expansion phase and that discrete changes in the FAC topology are observed in the late growth phase prior to auroral substorm expansion phase onset. These observations have important implications for determining how the magnetosphere and ionosphere couple during the late growth phase and expansion phase, as well as providing important constraints on the magnetospheric generator of the FACs comprising the SCW.

  14. The structure of apo human glutamate dehydrogenase details subunit communication and allostery.

    PubMed

    Smith, Thomas J; Schmidt, Timothy; Fang, Jie; Wu, Jane; Siuzdak, Gary; Stanley, Charles A

    2002-05-03

    The structure of human glutamate dehydrogenase (GDH) has been determined in the absence of active site and regulatory ligands. Compared to the structures of bovine GDH that were complexed with coenzyme and substrate, the NAD binding domain is rotated away from the glutamate-binding domain. The electron density of this domain is more disordered the further it is from the pivot helix. Mass spectrometry results suggest that this is likely due to the apo form being more dynamic than the closed form. The antenna undergoes significant conformational changes as the catalytic cleft opens. The ascending helix in the antenna moves in a clockwise manner and the helix in the descending strand contracts in a manner akin to the relaxation of an extended spring. A number of spontaneous mutations in this antenna region cause the hyperinsulinism/hyperammonemia syndrome by decreasing GDH sensitivity to the inhibitor, GTP. Since these residues do not directly contact the bound GTP, the conformational changes in the antenna are apparently crucial to GTP inhibition. In the open conformation, the GTP binding site is distorted such that it can no longer bind GTP. In contrast, ADP binding benefits by the opening of the catalytic cleft since R463 on the pivot helix is pushed into contact distance with the beta-phosphate of ADP. These results support the previous proposal that purines regulate GDH activity by altering the dynamics of the NAD binding domain. Finally, a possible structural mechanism for negative cooperativity is presented.

  15. A new Monte Carlo method for investigating geometrical structures of lipid membranes with atomistic detail

    NASA Astrophysics Data System (ADS)

    Cheng, Sara; Qiu, Liming; Cheng, K.; Vaughn, Mark

    2011-10-01

    The distribution statistics of the surface area, volume and voids of lipid molecules are important parameters to characterize the structures of self-assembling lipid membranes. Traditional methods are mostly based on various assumptions of the thickness of the lipid membrane and the volumes of certain types of lipid molecules. However, those methods usually lead to an over- or underestimation of the average surface area of lipid molecules when compared to the experimental results of the pure lipid systems. We developed a new Monte Carlo method that is able to estimate the distributions and averages of surface area, volume and void space of the lipid molecules in the absence and presence of proteins of the MD simulation results of lipid membranes at the atomistic scale. We successfully validated our new method on an ordered hard-sphere system and on a phospholipid/cholesterol binary lipid system, all with known structural parameters. Using this new method, the structural perturbation of the conformal annular lipids in close proximity to the embedded protein in a lipid/protein system will also be presented.

  16. Crystal structure of α5β1 integrin ectodomain: Atomic details of the fibronectin receptor

    PubMed Central

    Nagae, Masamichi; Re, Suyong; Mihara, Emiko; Nogi, Terukazu; Sugita, Yuji

    2012-01-01

    Integrin α5β1 is a major cellular receptor for the extracellular matrix protein fibronectin and plays a fundamental role during mammalian development. A crystal structure of the α5β1 integrin headpiece fragment bound by an allosteric inhibitory antibody was determined at a 2.9-Å resolution both in the absence and presence of a ligand peptide containing the Arg-Gly-Asp (RGD) sequence. The antibody-bound β1 chain accommodated the RGD ligand with very limited structural changes, which may represent the initial step of cell adhesion mediated by nonactivated integrins. Furthermore, a molecular dynamics simulation pointed to an important role for Ca2+ in the conformational coupling between the ligand-binding site and the rest of the molecule. The RGD-binding pocket is situated at the center of a trenchlike exposed surface on the top face of α5β1 devoid of glycosylation sites. The structure also enabled the precise prediction of the acceptor residue for the auxiliary synergy site of fibronectin on the α5 subunit, which was experimentally confirmed by mutagenesis and kinetic binding assays. PMID:22451694

  17. Detailed Post-Soft Impact Progressive Damage Assessment for Hybrid Structure Jet Engines

    NASA Technical Reports Server (NTRS)

    Siddens, Aaron; Bayandor, Javid; Celestina, Mark L.

    2014-01-01

    Currently, certification of engine designs for resistance to bird strike is reliant on physical tests. Predictive modeling of engine structural damage has mostly been limited to evaluation of individual forward section components, such as fan blades within a fixed frame of reference, to direct impact with a bird. Such models must be extended to include interactions among engine components under operating conditions to evaluate the full extent of engine damage. This paper presents the results of a study aim to develop a methodology for evaluating bird strike damage in advanced propulsion systems incorporating hybrid composite/metal structures. The initial degradation and failure of individual fan blades struck by a bird were investigated. Subsequent damage to other fan blades and engine components due to resultant violent fan assembly vibrations and fragmentation was further evaluated. Various modeling parameters for the bird and engine components were investigated to determine guidelines for accurately capturing initial damage and progressive failure of engine components. Then, a novel hybrid structure modeling approach was investigated and incorporated into the crashworthiness methodology. Such a tool is invaluable to the process of design, development, and certification of future advanced propulsion systems.

  18. Silicon Isotopes doping experiments to measure quartz dissolution and precipitation rates at equilibrium and test the principle of detailed balance

    NASA Astrophysics Data System (ADS)

    Zhu, C.; Rimstidt, J. D.; Liu, Z.; Yuan, H.

    2016-12-01

    The principle of detailed balance (PDB) has been a cornerstone for irreversible thermodynamics and chemical kinetics for a long time, and its wide application in geochemistry has mostly been implicit and without experimental testing of its applicability. Nevertheless, many extrapolations based on PDB without experimental validation have far reaching impacts on society's mega environmental enterprises. Here we report an isotope doping method that independently measures simultaneous dissolution and precipitation rates and can test this principle. The technique reacts a solution enriched in a rare isotope of an element with a solid having natural isotopic abundances (Beck et al., 1992; Gaillardet, 2008; Gruber et al., 2013). Dissolution and precipitation rates are found from the changing isotopic ratios. Our quartz experiment doped with 29Si showed that the equilibrium dissolution rate remains unchanged at all degrees of undersaturation. We recommend this approach to test the validity of using the detailed balance relationship in rate equations for other substances.

  19. Unraveling of a detailed-balance-preserved quantum master equation and continuous feedback control of a measured qubit

    NASA Astrophysics Data System (ADS)

    Luo, JunYan; Jin, Jinshuang; Wang, Shi-Kuan; Hu, Jing; Huang, Yixiao; He, Xiao-Ling

    2016-03-01

    We present a generic unraveling scheme for a detailed-balance-preserved quantum master equation applicable for stochastic point processes in mesoscopic transport. It enables us to investigate continuous measurement of a qubit on the level of single quantum trajectories, where essential correlations between the inherent dynamics of the qubit and detector current fluctuations are revealed. Based on this unraveling scheme, feedback control of the charge qubit is implemented to achieve a desired pure state in the presence of the detailed-balance condition. With sufficient feedback strength, coherent oscillations of the measured qubit can be maintained for arbitrary qubit-detector coupling. Competition between the loss and restoration of coherence entailed, respectively, by measurement back action and feedback control is reflected in the noise power spectrum of the detector's output. It is demonstrated unambiguously that the signal-to-noise ratio is significantly enhanced with increasing feedback strength and could even exceed the well-known Korotkov-Averin bound in quantum measurement. The proposed unraveling and feedback scheme offers a transparent and straightforward approach to effectively sustaining ideal coherent oscillations of a charge qubit in the field of quantum computation.

  20. Unusual Lipid A from a Cold-Adapted Bacterium: Detailed Structural Characterization.

    PubMed

    Casillo, Angela; Ziaco, Marcello; Lindner, Buko; Parrilli, Ermenegilda; Schwudke, Dominik; Holgado, Aurora; Verstrepen, Lynn; Sannino, Filomena; Beyaert, Rudi; Lanzetta, Rosa; Tutino, Maria Luisa; Corsaro, Maria Michela

    2017-06-26

    Colwellia psychrerythraea 34H is a Gram-negative cold-adapted microorganism that adopts many strategies to cope with the limitations associated with the low temperatures of its habitat. In this study, we report the complete characterization of the lipid A moiety from the lipopolysaccharide of Colwellia. Lipid A and its partially deacylated derivative were completely characterized by high-resolution mass spectrometry, NMR spectroscopy, and chemical analysis. An unusual structure with a 3-hydroxy unsaturated tetradecenoic acid as a component of the primary acylation pattern was identified. In addition, the presence of a partially acylated phosphoglycerol moiety on the secondary acylation site at the 3-position of the reducing 2-amino-2-deoxyglucopyranose unit caused tremendous natural heterogeneity in the structure of lipid A. Biological-activity assays indicated that C. psychrerythraea 34H lipid A did not show an agonistic or antagonistic effect upon testing in human macrophages. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  1. Detailed design of a lattice composite fuselage structure by a mixed optimization method

    NASA Astrophysics Data System (ADS)

    Liu, D.; Lohse-Busch, H.; Toropov, V.; Hühne, C.; Armani, U.

    2016-10-01

    In this article, a procedure for designing a lattice fuselage barrel is developed. It comprises three stages: first, topology optimization of an aircraft fuselage barrel is performed with respect to weight and structural performance to obtain the conceptual design. The interpretation of the optimal result is given to demonstrate the development of this new lattice airframe concept for the fuselage barrel. Subsequently, parametric optimization of the lattice aircraft fuselage barrel is carried out using genetic algorithms on metamodels generated with genetic programming from a 101-point optimal Latin hypercube design of experiments. The optimal design is achieved in terms of weight savings subject to stability, global stiffness and strain requirements, and then verified by the fine mesh finite element simulation of the lattice fuselage barrel. Finally, a practical design of the composite skin complying with the aircraft industry lay-up rules is presented. It is concluded that the mixed optimization method, combining topology optimization with the global metamodel-based approach, allows the problem to be solved with sufficient accuracy and provides the designers with a wealth of information on the structural behaviour of the novel anisogrid composite fuselage design.

  2. Study of effects of design details on structural response to acoustic excitation

    NASA Technical Reports Server (NTRS)

    Rudder, F. F., Jr.

    1972-01-01

    The normal mode vibration characteristics of one-dimensional and two-dimensional panel arrays were investigated analytically and experimentally. The finite element displacement method was used to formulate the structural models. The structural models include a stiffness and consistent mass matrix for thin-walled open-section beams not previously reported, and a modification of a rectangular plate bending element to include a fundamental interior mode for the element as a generalized coordinate. Provision for adding lumped masses to represent accelerometers is also included. For the one-dimensional panel, the normal mode stress resultants are obtained by integrating the equilibrium equations directly. For the two-dimensional panel arrays, the solution for the stress resultants in the cover sheet was attempted by introducing stress functions dependent upon the displacement field of the plate element. This approach, although incomplete, is a natural extension of the one-dimensional analysis for plate elements. The exerimental program which was used to verify the analysis is described and experimental results are compared with the analysis.

  3. A detailed three-dimensional P-wave velocity structure in Italy from local earthquake tomography

    NASA Astrophysics Data System (ADS)

    di Stefano, Raffaele; Castello, Barbara; Chiarabba, Claudio; Grazia Ciaccio, Maria

    2010-05-01

    We here present an updated high resolution tomographic P-wave velocity model of the lithosphere in Italy, obtained by adding about 296,600 P-wave arrival observations from ~7.200 earthquakes, from the preliminary update of the CSI 2.0, recorded in the period 2003-2007, to the previously inverted dataset (165,000 P-wave arrivals).Additional events have been strictly selected for location quality (azimuthal gap < 135°; horizontal error <= 2km; vertical error <= 4km; rms < 1s) and a number of P-wave observations >= 8. Our results confirm the main structural features in the best resolved parts of the inverted volume and show a much better resolution in some of the previously less resolved areas, due to both the larger number of inverted phases and the more even distribution of seismic stations. Surface basins and relationships between the Adriatic, Tyrrhenian, and European plates are better imaged. The integrated analysis of 20 years of seismicity and the high resolution tomographic images obtained, allows us to add new constraints to the kynematics and the geodynamics of the lithosphere-asthenosphere system in this region. We also present preliminary results obtained by thickening the nodes spacing from 15km x15km to 10km x 10km and we finally compare the complex velocity structures imaged by the inversion of the two different grid spacing.

  4. Unveiling details of defect structures in chiral and achiral nematic droplets by improving simulations of optical images

    NASA Astrophysics Data System (ADS)

    Mur, Urban; Čopar, Simon; Ravnik, Miha; Čančula, Miha; Žumer, Slobodan

    2016-09-01

    There is a great increase of interest in the nematic defect structures, where interplay of confinement, elasticity, anchoring, and chirality leads to complex ordering fields with singular topological defects and nonsingular solitonic deformations. Beside numerous advanced microscopy techniques, the standard polarized optical microscopy is still an elementary first-to-take tool in use. To fully capture its potential and understand the limitations in unveiling the details of complex structures, we apply a recently extended Jones matrix approach based on ray-tracing that allows to include also effects of focusing and numerical aperture. The approach is illustrated with results of recent studies of cholesteric droplets.

  5. Deciphering fine molecular details of proteins' structure and function with a Protein Surface Topography (PST) method.

    PubMed

    Koromyslova, Anna D; Chugunov, Anton O; Efremov, Roman G

    2014-04-28

    Molecular surfaces are the key players in biomolecular recognition and interactions. Nowadays, it is trivial to visualize a molecular surface and surface-distributed properties in three-dimensional space. However, such a representation trends to be biased and ambiguous in case of thorough analysis. We present a new method to create 2D spherical projection maps of entire protein surfaces and manipulate with them--protein surface topography (PST). It permits visualization and thoughtful analysis of surface properties. PST helps to easily portray conformational transitions, analyze proteins' properties and their dynamic behavior, improve docking performance, and reveal common patterns and dissimilarities in molecular surfaces of related bioactive peptides. This paper describes basic usage of PST with an example of small G-proteins conformational transitions, mapping of caspase-1 intersubunit interface, and intrinsic "complementarity" in the conotoxin-acetylcholine binding protein complex. We suggest that PST is a beneficial approach for structure-function studies of bioactive peptides and small proteins.

  6. Detailed Analysis of the Structural Changes of Bone Matrix During the Demineralization Process Using Raman Spectroscopy

    NASA Astrophysics Data System (ADS)

    Timchenko, E. V.; Zherdeva, L. A.; Timchenko, P. E.; Volova, L. T.; Ponomareva, U. V.

    The results of experimental research of human cortical bone tissue depending on demineralization time were represented using Raman spectroscopy. Depending on demineralization time the ratio of the mineral (РO43- and CO32-) and organic components (amide I) of bone tissue, as well as changes in the spectral regions responsible for the structural integrity of the collagen fibers in bone tissue (1200-1460 cm-1 and 2880-3000 cm-1) were investigated. The observed changes show a decrease in mineral components: thus, the value of Raman band intensity at 956 and 1069 cm-1 for 5 minutes demineralization is 68.5 and 77.3%, for 20 minutes - 55.1 and 61.1%, for 120 minutes - 32.8 and 37% from Raman intensity values of not demineralized tissue objects respectively.

  7. The dimeric proto-ribosome: Structural details and possible implications on the origin of life.

    PubMed

    Agmon, Ilana

    2009-06-30

    A symmetric pocket-like entity, composed of two L-shaped RNA units, encircles the peptide synthesis site within the contemporary ribosome. This entity was suggested to be the vestige of a dimeric proto-ribosome, which could have formed spontaneously in the prebiotic world, catalyzing non-coded peptide bond formation and elongation. This structural element, beyond offering the initial step in the evolution of translation, is hypothesized here to be linked to the origin of life. By catalyzing the production of random peptide chains, the proto-ribosome could have enabled the formation of primary enzymes, launching a process of co-evolution of the translation apparatus and the proteins, thus presenting an alternative to the RNA world hypothesis.

  8. Preliminary System Development and Detailed Structural Design and Analysis for the CanX-7 Nanosatellite

    NASA Astrophysics Data System (ADS)

    Singarayar, Fiona

    Satellites placed in LEO can remain there for an indefinite period of time. To reduce the density of this orbit so as to avoid potential collisions with other satellites, the IADC has published a report that suggests any satellite in LEO should de-orbit within 25 years. CanX-7 is a de-orbiting technology demonstration mission intended to help solve the global space debris problem. The work summarized in this thesis describes the author's contribution to the CanX-7 preliminary system development, as well as to the deployment detection and structural subsystems. Discussed herein are the challenges of carrying forward multiple designs in parallel and the factors and design trades that aid the decision-making process. This thesis not only presents the description of the final design of the nanosatellite, but also the evolution of the spacecraft from when it was initially envisioned in 2010 to its current state at the time of this writing.

  9. Emergence and detailed structure of terraced surfaces produced by oblique-incidence ion sputtering

    NASA Astrophysics Data System (ADS)

    Harrison, Matt P.; Pearson, Daniel A.; Bradley, R. Mark

    2017-09-01

    We study the nanoscale terraced topographies that arise when a solid surface is bombarded with a broad ion beam that has a relatively high angle of incidence θ . We find that the surface is not completely flat between the regions in which the surface slope changes rapidly with position: Instead, small-amplitude ripples propagate along the surface. Our analytical work on these ripples yields their propagation velocity as well as the scaling behavior of their amplitude. Our simulations establish that the surfaces exhibit interrupted coarsening, i.e., the characteristic width and height of the surface disturbance grow for a time but ultimately asymptote to finite values as the fully terraced state develops. In addition, as θ is reduced, the surface can undergo a transition from a terraced morphology that changes little with time as it propagates over the surface to an unterraced state that appears to exhibit spatiotemporal chaos. For different ranges of the parameters, our equation of motion produces unterraced topographies that are remarkably similar to those seen in various experiments, including pyramidal structures that are elongated along the projected beam direction and isolated lenticular depressions.

  10. Detailed Structure of the Outer Disk Around HD 169142 with Polarized Light in H-band

    NASA Technical Reports Server (NTRS)

    Momose, Munetake; Morita, Ayaka; Fukagawa, Misato; Muto, Takayuki; Takeuchi, Taku; Hashimoto, Jun; Honda, Mitsuhiko; Kudo, Tomoyuki; Okamoto, Yoshiko K.; Kanagawa, Kazuhiro D.; Tanaka, Hidekazu; Grady, Carol A.; Sitko, Michael L.; Akiyama, Eiji; Currie, Thayne; Follette, Katherine B.; Mayama, Satoshi; Kusakabe, Nobuhiko; Abe, Lyu; Brandner, Wolfgang; Brandt, Timothy D.; Carson, Joseph C.; Egner, Sebastian; Feldt, Markus; McElwain, Michael W.

    2015-01-01

    Coronagraphic imagery of the circumstellar disk around HD 169142 in H-band polarized intensity (PI) with Subaru/HiCIAO is presented. The emission scattered by dust particles at the disk surface in 0.''2=r=1.''2, or 29=r=174 AU, is successfully detected. The azimuthally-averaged radial profile of the PI shows a double power-law distribution, in which the PIs in r = 29-52 AU and r = 81.2-145 AU respectively show r-3-dependence. These two power-law regions are connected smoothly with a transition zone (TZ), exhibiting an apparent gap in r = 40-70 AU. The PI in the inner power-law region shows a deep minimum whose location seems to coincide with the point source at lambda = 7 mm. This can be regarded as another sign of a protoplanet in TZ. The observed radial profile of the PI is reproduced by a minimally flaring disk with an irregular surface density distribution or with an irregular temperature distribution or with the combination of both. The depletion factor of surface density in the inner power-law region (r <50 AU) is derived to be =0.16 from a simple model calculation. The obtained PI image also shows small scale asymmetries in the outer power-law region. Possible origins for these asymmetries include corrugation of the scattering surface in the outer region, and shadowing effect by a puffed up structure in the inner power-law region.

  11. Conjugation of α-amylase with dextran for enhanced stability: process details, kinetics and structural analysis.

    PubMed

    Jadhav, Swati B; Singhal, Rekha S

    2012-11-06

    The influence of enzyme polysaccharide interaction on enzyme stability and activity was elucidated by covalently binding dextran to a model enzyme, α-amylase. The conjugation process was optimized with respect to concentration of oxidizing agent, pH of enzyme solution, ratio of dextran to enzyme concentration, temperature and time of conjugate formation, and was found to affect the stability of α-amylase. α-Amylase conjugated under optimized conditions showed 5% loss of activity but with enhanced thermal and pH stability. Lower inactivation rate constant of conjugated α-amylase within the temperature range of 60-80 °C implied its better stability. Activation energy for denaturation of α-amylase increased by 8.81 kJ/mol on conjugation with dextran. Analysis of secondary structure of α-amylase after covalent binding with dextran showed helix to turn conversion without loss of functional properties of α-amylase. Covalent bonding was found to be mandatory for the formation of conjugate.

  12. Validation of brief questionnaire measures of sun exposure and skin pigmentation against detailed and objective measures including vitamin D status.

    PubMed

    Cargill, Jessica; Lucas, Robyn M; Gies, Peter; King, Kerryn; Swaminathan, Ashwin; Allen, Martin W; Banks, Emily

    2013-01-01

    Self-reported sun exposure is commonly used in research, but how well this represents actual sun exposure is poorly understood. From February to July 2011, a volunteer sample (n = 47) of older adults (≥45 years) in Canberra, Australia, answered brief questions on time outdoors (weekdays and weekends) and natural skin color. They subsequently maintained a sun diary and wore an ultraviolet radiation (UVR) digital dosimeter for 7 days. Melanin density was estimated using reflectance spectrophotometry; lifetime sun damage was assessed using silicone casts of the back of the hand; and serum 25-hydroxyvitamin D (25(OH)D) concentration was assayed. Questionnaire-reported time outdoors correlated significantly with diary-recorded time outdoors (Spearman correlation r(s) = 0.66; 95% CI 0.46, 0.80; P < 0.001) and UVR dosimeter dose (r(s ) = 0.46; 95% CI 0.18, 0.68; P = 0.003), but not 25(OH)D concentration (r(s) = 0.24; 95% CI -0.05, 0.50; P = 0.10). Questionnaire-reported untanned skin color correlated significantly with measured melanin density at the inner upper arm (r(s) = 0.49; 95% CI 0.24, 0.68; P < 0.001). In a multiple linear regression model, statistically significant predictors of 25(OH)D concentration were self-reported frequency of physical activity, skin color and recent osteoporosis treatment (R(2) = 0.54). In this study, brief questionnaire items provided valid rankings of sun exposure and skin color, and enabled the development of a predictive model for 25(OH)D concentration.

  13. Effect of detailed cell structure on light scattering distribution: FDTD study of a B-cell with 3D structure constructed from confocal images

    NASA Astrophysics Data System (ADS)

    Brock, R. Scott; Hu, Xin-Hua; Weidner, Douglas A.; Mourant, Judith R.; Lu, Jun Q.

    2006-11-01

    Human B-cells play an important role in the immune system, and because of their relatively simple structures with a nearly spherically shaped cell membrane and a large nucleus, they provide a good case to study on how the details of cell structure affect light scattering properties. A finite-difference-time-domain (FDTD) method is used to calculate angle-resolved light scattering distributions from a B-cell. Published FDTD simulations to date have used a smooth shape with a certain degree of symmetry to approximate the actual cell shape. In contrast, for this work, the shapes of the cell and its nucleus were determined from confocal microscopy measurements. An automated procedure was developed to construct a realistic three-dimensional structure of a B-cell from a stack of two-dimensional confocal images. The angle-resolved Mueller matrix elements of the B-cell were calculated and averaged for 30 different angles of incidence using a parallel FDTD code. These results were compared with those from a homogeneous and a coated sphere. Scattering from the two sphere models and the B-cell were very similar for scattering angles less than 5°, and the coated sphere and B-cell agreed well for scattering angles up to 20°. However, at larger angles, the scattering from the B-cell was a much smoother function of angle than scattering from either sphere model. Additionally, the homogeneous sphere results were the most similar to the B-cell results for most angles between 120° and 150°, and at angles greater than 150°, the B-cell scattered more light than either of the spheres. These results yield strong evidence that accurate modeling of light scattering by biological cells requires not only the high accuracy of the employed numerical method but the realistic cellular structure as input information as well.

  14. Detailed studies on substrate structure requirements of glycoamidases A and F.

    PubMed

    Fan, J Q; Lee, Y C

    1997-10-24

    Glycoamidases (peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase, EC 3.5.1.52; also known as peptide: N-glycanases (PNGases) release N-linked oligosaccharides from glycopeptides and/or glycoproteins by hydrolyzing the glycosylated beta-amide bond of the asparagine side chain. The most widely used glycoamidases are those from Flavobacterium meningosepticum (glycoamidase F or PNGase F) and almond emulsin (glycoamidase A or PNGase A). To study the substrate structure requirement of these enzymes systematically, we synthesized >30 glycopeptides containing cellobiose, lactose, GlcNAc, and di-N,N'-acetylchitobiose (CTB). The length of the peptide was varied from one to five amino acids, and glycosylamines were linked to either Asn or Gln located at different positions in the peptide, including NH2 and COOH termini. Neither enzyme could cleave cellobiose and lactose glycopeptides, indicating that the 2-acetamido group on the Asn-linked GlcNAc is important in the recognition by both glycoamidases A and F. GlcNAc peptides could be cleaved by both enzymes, albeit not as effectively as CTB glycopeptides. Neither enzyme requires the Asn-Xaa-(Ser/Thr) sequence (required for N-glycosylation) for activity. Glycoamidase A could even hydrolyze a Gln-bound CTB glycopeptide, whereas the action of glycoamidase F on this substrate is minimal. While glycoamidase A could act on CTB dipeptides, glycoamidase F preferred a tripeptide or longer. The Km and Vmax values of glycoamidase A for t-butoxycarbonyl-(CTB)-Asn-Ala-Ser-OMe were 2.1 mM and 0.66 micromol/min/mg, respectively. A natural glycodipeptide, Man9-GlcNAc2-Asn-Phe, was also completely hydrolyzed by glycoamidase A.

  15. Detailed structure of the outer disk around HD 169142 with polarized light in H-band

    NASA Astrophysics Data System (ADS)

    Momose, Munetake; Morita, Ayaka; Fukagawa, Misato; Muto, Takayuki; Takeuchi, Taku; Hashimoto, Jun; Honda, Mitsuhiko; Kudo, Tomoyuki; Okamoto, Yoshiko K.; Kanagawa, Kazuhiro D.; Tanaka, Hidekazu; Grady, Carol A.; Sitko, Michael L.; Akiyama, Eiji; Currie, Thayne; Follette, Katherine B.; Mayama, Satoshi; Kusakabe, Nobuhiko; Abe, Lyu; Brandner, Wolfgang; Brandt, Timothy D.; Carson, Joseph C.; Egner, Sebastian; Feldt, Markus; Goto, Miwa; Guyon, Olivier; Hayano, Yutaka; Hayashi, Masahiko; Hayashi, Saeko S.; Henning, Thomas; Hodapp, Klaus W.; Ishii, Miki; Iye, Masanori; Janson, Markus; Kandori, Ryo; Knapp, Gillian R.; Kuzuhara, Masayuki; Kwon, Jungmi; Matsuo, Taro; McElwain, Michael W.; Miyama, Shoken; Morino, Jun-Ichi; Moro-Martin, Amaya; Nishimura, Tetsuo; Pyo, Tae-Soo; Serabyn, Eugene; Suenaga, Takuya; Suto, Hiroshi; Suzuki, Ryuji; Takahashi, Yasuhiro H.; Takami, Michihiro; Takato, Naruhisa; Terada, Hiroshi; Thalmann, Christian; Tomono, Daigo; Turner, Edwin L.; Watanabe, Makoto; Wisniewski, John; Yamada, Toru; Takami, Hideki; Usuda, Tomonori; Tamura, Motohide

    2015-10-01

    Coronagraphic imagery of the circumstellar disk around HD 169142 in H-band polarized intensity (PI) with Subaru/HiCIAO is presented. The emission scattered by dust particles at the disk surface in 0{^''.}2 ≤ r ≤ 1{^''.}2, or 29 ≤ r ≤ 174 au, is successfully detected. The azimuthally averaged radial profile of the PI shows a double power-law distribution, in which the PIs in r = 29-52 au and r = 81.2-145 au respectively show r-3 dependence. These two power-law regions are connected smoothly with a transition zone (TZ), exhibiting an apparent gap in r = 40-70 au. The PI in the inner power-law region shows a deep minimum whose location seems to coincide with the point source at λ = 7 mm. This can be regarded as another sign of a protoplanet in the TZ. The observed radial profile of the PI is reproduced by a minimally flaring disk with an irregular surface density distribution, an irregular temperature distribution, or with a combination of both. The depletion factor of surface density in the inner power-law region (r < 50 au) is derived to be ≥ 0.16 from a simple model calculation. The obtained PI image also shows small-scale asymmetries in the outer power-law region. Possible origins for these asymmetries include corrugation of the scattering surface in the outer region, and a shadowing effect by a puffed-up structure in the inner power-law region.

  16. Calculation of stellar structure. IV. Results using a detailed energy generation subroutine.

    NASA Astrophysics Data System (ADS)

    Rouse, C. A.

    1995-12-01

    The results from two solar model calculations using the "energy.for" energy generation and neutrino flux code (Bahcall & Pinsonneault 1992) are presented. The models of the present Sun were generated using the program described in the first three papers of this series and using only the helium abundance profile from the Bahcall & Ulrich (1988) (BU) standard model in the present model structure calculations. One model is a simulation of the BU model and yields a ^37^Cl solar neutrino counting rate of 7.0SNU (compared to 7.9SNU for the BU model) and a ^71^Ga neutrino experiment counting rate between 112 and 137SNU (compared to 132SNU for the BU model). The second model has a postulated small high-Z core (Rouse 1983) and yields a ^37^Cl neutrino experiment counting rate of 2.45SNU that is within one sigma of the Homestake Collaboration observed rate of (2.55+/-0.25)SNU (see Parke 1995). It yields a ^71^Ga neutrino experiment counting rate between 89 and 103SNU that is within one sigma of the GALLEX Collaboration neutrino experiment observed rate of (79+/-12)SNU (see Parke 1995). The theoretical ^8^B solar neutrino flux and the observed Kamiokande ^8^B flux (Hirata et al. 1989) are discussed regarding the puzzle of explaining both the chlorine experiment results and the Kamiokande results. The modification of the energy.for code for use in the current Rouse program is described. Consistency of a high-Z core solar model with theories of star formation from pre-stellar nuclei (Krat 1952; Urey 1956; Huang 1957) is suggested.

  17. NMR Crystallography of Enzyme Active Sites: Probing Chemically-Detailed, Three-Dimensional Structure in Tryptophan Synthase

    PubMed Central

    Dunn, Michael F.

    2013-01-01

    Conspectus NMR crystallography – the synergistic combination of X-ray diffraction, solid-state NMR spectroscopy, and computational chemistry – offers unprecedented insight into three-dimensional, chemically-detailed structure. From its initial role in refining diffraction data of organic and inorganic solids, NMR crystallography is now being developed for application to active sites in biomolecules, where it reveals chemically-rich detail concerning the interactions between enzyme site residues and the reacting substrate that is not achievable when X-ray, NMR, or computational methodologies are applied in isolation. For example, typical X-ray crystal structures (1.5 to 2.5 Å resolution) of enzyme-bound intermediates identify possible hydrogen-bonding interactions between site residues and substrate, but do not directly identify the protonation state of either. Solid-state NMR can provide chemical shifts for selected atoms of enzyme-substrate complexes, but without a larger structural framework in which to interpret them, only empirical correlations with local chemical structure are possible. Ab initio calculations and molecular mechanics can build models for enzymatic processes, but rely on chemical details that must be specified. Together, however, X-ray diffraction, solid-state NMR spectroscopy, and computational chemistry can provide consistent and testable models for structure and function of enzyme active sites: X-ray crystallography provides a coarse framework upon which models of the active site can be developed using computational chemistry; these models can be distinguished by comparison of their calculated NMR chemical shifts with the results of solid-state NMR spectroscopy experiments. Conceptually, each technique is a puzzle piece offering a generous view of the big picture. Only when correctly pieced together, however, can they reveal the big picture at highest resolution. In this Account, we detail our first steps in the development of NMR

  18. Detailed measurement of the magnitude and orientation of thermal gradients in lined boreholes for characterizing groundwater flow in fractured rock

    NASA Astrophysics Data System (ADS)

    Pehme, Peeter; Parker, Beth L.; Cherry, John A.; Blohm, Detlef

    2014-05-01

    Recent developments have led to revitalization of the use of temperature logging for characterizing flow through fractured rock. The sealing of boreholes using water-filled, flexible impermeable liners prevents vertical cross connection between fractures intersecting the hole and establishes a static water column with a temperature stratification that mimics that in the surrounding formation. Measurement of the temperature profile of the lined-hole, water column (using a high sensitivity single-point probe achieving resolution on the order of 0.001 °C) has identified fractures with active flow under ambient groundwater conditions (without cross connecting flow along the borehole). Detection of flow in fractures was further improved with the use of a heater to create thermal disequilibrium in the active line source (ALS) technique and eliminate normal depth limitations in the process. This paper presents another advancement; detailed measurement of the magnitude and direction of the thermal gradient to characterize flow through fractured rock. The temperature within the water column is measured along the length of the lined hole using a temperature vector probe (TVP): four high sensitivity sensors arranged in a tetrahedral pattern oriented using three directional magnetometers. Based on these data, the horizontal and vertical components of the thermal field, as well as the direction of temperature gradient are determined, typically at depth intervals of less than 0.01 m. This probe was assessed and refined by trials in over 30 lined boreholes; the results from two holes through a fractured dolostone aquifer in Guelph, Ontario are used as exampled. Since no other device exists for measuring flow magnitude and direction under the ambient flow condition created by lined holes, the performance of the TVP is assessed by examining the reproducibility of the temperature measurements through an ALS test, and by the consistency of the results relative to other types of

  19. EM-fold: de novo atomic-detail protein structure determination from medium-resolution density maps.

    PubMed

    Lindert, Steffen; Alexander, Nathan; Wötzel, Nils; Karakaş, Mert; Stewart, Phoebe L; Meiler, Jens

    2012-03-07

    Electron density maps of membrane proteins or large macromolecular complexes are frequently only determined at medium resolution between 4 Å and 10 Å, either by cryo-electron microscopy or X-ray crystallography. In these density maps, the general arrangement of secondary structure elements (SSEs) is revealed, whereas their directionality and connectivity remain elusive. We demonstrate that the topology of proteins with up to 250 amino acids can be determined from such density maps when combined with a computational protein folding protocol. Furthermore, we accurately reconstruct atomic detail in loop regions and amino acid side chains not visible in the experimental data. The EM-Fold algorithm assembles the SSEs de novo before atomic detail is added using Rosetta. In a benchmark of 27 proteins, the protocol consistently and reproducibly achieves models with root mean square deviation values <3 Å.

  20. Economic gains from targeted measures related to non-point pollution in agriculture based on detailed nitrate reduction maps.

    PubMed

    Jacobsen, Brian H; Hansen, Anne Lausten

    2016-06-15

    From 1990 to 2003, Denmark reduced N-leaching from the root zone by 50%. However, more measures are required, and in recent years, the focus has been on how to differentiate measures in order to ensure that they are implemented where the effect on N-loss reductions per ha is the greatest. The purpose of the NiCA project has been to estimate the natural nitrate reduction in the groundwater more precisely than before using a plot size down to 1ha. This article builds on these findings and presents the possible economic gains for the farmer when using this information to reach a given N-loss level. Targeted measures are especially relevant where the subsurface N-reduction varies significantly within the same farm and national analyses have shown that a cost reduction of around 20-25% using targeted measures is likely. The analyses show an increasing potential with increasing variation in N-reduction in the catchment. In this analysis, the knowledge of spatial variation in N-reduction potential is used to place measures like catch crops or set-a-side at locations with the greatest effect on 10 case farms in the Norsminde Catchment, Denmark. The findings suggest that the gains are from 0 to 32€/ha and the average farm would gain approximately 14-21€/ha/year from the targeted measures approach. The analysis indicates that the economic gain is greater than the costs of providing the detailed maps of 5-10€/ha/year. When N-loss reduction requirements are increased, the economic gains are greater. When combined with new measures like mini-wetlands and early sowing the economic advantage is increased further. The paper also shows that not all farms can use the detailed information on N-reduction and there is not a clear link between spatial variation in N-reduction at the farm level and possible economic gains for all these 10 farms. Copyright © 2016 Elsevier B.V. All rights reserved.

  1. Shaft Diameter Measurement Using Structured Light Vision

    PubMed Central

    Liu, Siyuan; Tan, Qingchang; Zhang, Yachao

    2015-01-01

    A method for measuring shaft diameters is presented using structured light vision measurement. After calibrating a model of the structured light measurement, a virtual plane is established perpendicular to the measured shaft axis and the image of the light stripe on the shaft is projected to the virtual plane. On the virtual plane, the center of the measured shaft is determined by fitting the projected image under the geometrical constraints of the light stripe, and the shaft diameter is measured by the determined center and the projected image. Experiments evaluated the measuring accuracy of the method and the effects of some factors on the measurement are analyzed. PMID:26274963

  2. Shaft Diameter Measurement Using Structured Light Vision.

    PubMed

    Liu, Siyuan; Tan, Qingchang; Zhang, Yachao

    2015-08-12

    A method for measuring shaft diameters is presented using structured light vision measurement. After calibrating a model of the structured light measurement, a virtual plane is established perpendicular to the measured shaft axis and the image of the light stripe on the shaft is projected to the virtual plane. On the virtual plane, the center of the measured shaft is determined by fitting the projected image under the geometrical constraints of the light stripe, and the shaft diameter is measured by the determined center and the projected image. Experiments evaluated the measuring accuracy of the method and the effects of some factors on the measurement are analyzed.

  3. First Results from Detailed Electric and Magnetic Field Measurements of the Interaction of a Laser-Produced and Ambient Plasma

    NASA Astrophysics Data System (ADS)

    Schaeffer, D. B.; Hofer, L. R.; Heuer, P. V.; Constantin, C. G.; Bondarenko, A. S.; Everson, E. T.; Clark, S. E.; Gekelman, W.; Niemann, C.

    2015-11-01

    Utilizing high-repetition lasers combined with a high-repetition ambient plasma allows for detailed 3D scans of the interaction of the laser-produced and ambient plasmas. We present the first results from experiments combining a newly-commissioned high-repetition (1 Hz) laser with the 1 Hz ambient plasma of the Large Plasma Device (LAPD) at the University of California, Los Angeles. The laser (20 J, 14 ns) was focused on a cylindrical plastic target embedded in the ambient LAPD plasma, resulting in an ablated debris-plasma that expanded perpendicular to the background magnetic field. The debris-ambient plasma interaction was studied with 3-axis magnetic flux probes, mounted on a 3D motion drive for detailed, high-resolution planar scans both along and perpendicular to the background field. Measurements were also taken using filtered fast-gate (ns) imaging, emissive Langmuir probes, and emissive spectroscopy. The results show that the debris ions are de-energized inside the diamagnetic cavity, while the ambient ions are accelerated through laminar electric fields.

  4. Measurements of glottal structure dynamics

    NASA Astrophysics Data System (ADS)

    Holzrichter, John F.; Ng, Lawrence C.; Burke, Gerry J.; Champagne, Nathan J.; Kallman, Jeffrey S.; Sharpe, Robert M.; Kobler, James B.; Hillman, Robert E.; Rosowski, John J.

    2005-03-01

    Low power, radarlike electromagnetic (EM) wave sensors, operating in a homodyne interferometric mode, are being used to measure tissue motions in the human vocal tract during speech. However, when these and similar sensors are used in front of the laryngeal region during voiced speech, there remains an uncertainty regarding the contributions to the sensor signal from vocal fold movements versus those from pressure induced trachea-wall movements. Several signal-source hypotheses are tested by performing experiments with a subject who had undergone tracheostomy, and who still was able to phonate when her stoma was covered (e.g., with a plastic plate). Laser-doppler motion-measurements of the subject's posterior trachea show small tissue movements, about 15 microns, that do not contribute significantly to signals from presently used EM sensors. However, signals from the anterior wall do contribute. EM sensor and air-pressure measurements, together with 3-D EM wave simulations, show that EM sensors measure movements of the vocal folds very well. The simulations show a surprisingly effective guiding of EM waves across the vocal fold membrane, which, upon glottal opening, are interrupted and reflected. These measurements are important for EM sensor applications to speech signal de-noising, vocoding, speech recognition, and diagnostics. .

  5. Hyperfine Structure measurements of 45Sc

    NASA Astrophysics Data System (ADS)

    Jones, K. D.; Rossi, D. M.; Minamisono, K.; Miller, A. J.; Asberry, H.; Mantica, P. F.

    2015-10-01

    A chain of charge radii shows discontinuity at nucleon magic numbers. This signature of the shell closure, however, is missing at the neutron magic number N = 20 for Ar, Ca and K isotopes. A collinear laser spectroscopy experiment on the stable 45Sc isotope, which is one proton added to Ca, was performed as a prerequisite of radioactive beam experiments on Sc across N = 20 to further investigate the abnormal behavior. The experiment was performed at BEam COoling and LAser spectroscopy (BECOLA) facility at NSCL and a hyperfine spectrum was measured for the electronic transition of 3 d 4 s 3D1 --> 3 d 4 p 3F2 at λ = 364 . 3 nm in 45ScII. The magnetic dipole and electric quadrupole hyperfine coupling constants A and B of both the lower and upper states were obtained from the hyperfine structure by fitting a pseudo-Voigt profile. The results obtained from these data are in good agreement with previous values and have smaller statistical errors. The detail of experiment and analysis will be discussed. This work was supported in part by NSF Grant No. PHY-11-02511.

  6. Coronal Structures Observed by Radio Propagation Measurements

    NASA Technical Reports Server (NTRS)

    Woo, R.

    1995-01-01

    This paper summarizes (1) advances in our knowledge of coronal structures inferred from radio propagation measurements, and (2) gains in our understanding of the relationship between radio propagation and white-light coronagraph measurements. Radio propagation measurements confirm that streamers are ray-like structures as depicted in coronagraph pictures, but also reveal a hierarchy of filamentary structures throughout the corona, extending from the size of streamers down to scale sizes as small as about 1 km at the Sun (10(ghe) arcsec). Doppler scintillation measurements, therefore, open a new window on small-scale structure that has long eluded coronagraph measurements. In addition, high precision ranging measurements make it possible to investigate large-scale structures not yet observed in corona graphs, such as plumes in equatorial coronal regions.

  7. Structural measures for multiplex networks

    NASA Astrophysics Data System (ADS)

    Battiston, Federico; Nicosia, Vincenzo; Latora, Vito

    2014-03-01

    Many real-world complex systems consist of a set of elementary units connected by relationships of different kinds. All such systems are better described in terms of multiplex networks, where the links at each layer represent a different type of interaction between the same set of nodes rather than in terms of (single-layer) networks. In this paper we present a general framework to describe and study multiplex networks, whose links are either unweighted or weighted. In particular, we propose a series of measures to characterize the multiplexicity of the systems in terms of (i) basic node and link properties such as the node degree, and the edge overlap and reinforcement, (ii) local properties such as the clustering coefficient and the transitivity, and (iii) global properties related to the navigability of the multiplex across the different layers. The measures we introduce are validated on a genuinely multiplex data set of Indonesian terrorists, where information among 78 individuals are recorded with respect to mutual trust, common operations, exchanged communications, and business relationships.

  8. Application of detailed temperature profile measurements for improving data quality check by Bowen Ratio/Energy Balance method

    NASA Astrophysics Data System (ADS)

    Pozníková, Gabriela; Fischer, Milan; Orság, Matěj; Trnka, Miroslav; Žalud, Zdeněk

    2015-04-01

    Water plays a key role in the functionality and sustainability of the ecosystems. In the light of the predicted climate change research should be focused on the water cycle and its individual components. Apart from the runoff, the major component of the water balance which drives the water from the ecosystems is represented by the evapotranspiration (ET). One of the standard methods for measuring ET is Bowen Ratio/Energy Balance method (BREB). It is based on the assumption that the water vapour and heat are transported by identical eddies with equal efficiency. In fact, this basic premise is based on a more complicated Monin-Obukhov similarity theory that explains the relationship between the profiles of wind, temperature and water vapour in the surface layer of the atmosphere. When BREB method is used we assume that the profiles of temperature and air humidity are ideally logarithmic or at least consistent. However, as this method is usually based on the measurements of temperature and humidity in only two heights, it is difficult to verify this assumption. We therefore conducted a field experiment using 4m high measurement-mast with 20 thermocouples connected to data-logger for detailed measurement of air temperature profile above different covers, e.g. grassland, spring barley, poplar plantation. The main goal of our effort was to capture so called "kink" in the profile of the temperature and verify if the assumptions made by BREB hold under various weather conditions and over different canopies testing the basic requirements of the BREB method use. Finally we devised a technique improving data selection for subsequent ET calculation. This study was funded by project "Building up a multidisciplinary scientific team focused on drought" No. CZ.1.07/2.3.00/20.0248,PASED - project supported by Czech program KONTAKT II No. LH12037 "Development of models for assessment of abiotic stresses in selected bioenergy plants" and LD130030 project supporting COST action ES1106.

  9. Measurement of elastic 12C+alpha scattering: details of the experiment, analysis, and discussion of phase shifts

    SciTech Connect

    Couture, Aaron Joseph; Detwiler, Rebecca; Gorres, Joachim; Stech, Edward J; Ugalde, Claudio; Wiescher, Michael C F; Heil, Michael; Kappeler, Franz; Azuma, Richard E; Buchmann, Lothar

    2009-01-01

    Recent global analyses of {sup 12}C({alpha},{gamma}){sup 16}O have incorporated both elastic-scallering and {beta}-decay data in addition to direct measurements. In that context, it has been shown that an improvement in the available elastic-scallering data could help determine the contribution of the two subthreshold states, 6.92(2{sup +}) and 7.12(1{sup -}) MeV, and with excellent statistics could restrict resonance parameters above the threshold. To this end angular distributions of {sup 12}C({alpha}, {alpha}){sup 12}C in the {alpha}-energy range of 2.6-8.2 MeV, at angles from 24 to 166 have been measured at the University of Notre Dame using an array of 32 silicon detectors. Details of the experiment are reported. In the present analysis, the phase shifts have been determined from our previously reported R-matrix fit to these data. The uncertainties in the R-matrix phase shifts ({ell} = 0...6) are derived by a new Monte Carlo analysis technique as described in the article. We provide these phase shifts here for general use, in particular for the improved analysis and extrapolation of the {alpha} radiative capture to low energies.

  10. An image-based model of the whole human heart with detailed anatomical structure and fiber orientation.

    PubMed

    Deng, Dongdong; Jiao, Peifeng; Ye, Xuesong; Xia, Ling

    2012-01-01

    Many heart anatomy models have been developed to study the electrophysiological properties of the human heart. However, none of them includes the geometry of the whole human heart. In this study, an anatomically detailed mathematical model of the human heart was firstly reconstructed from the computed tomography images. In the reconstructed model, the atria consisted of atrial muscles, sinoatrial node, crista terminalis, pectinate muscles, Bachmann's bundle, intercaval bundles, and limbus of the fossa ovalis. The atrioventricular junction included the atrioventricular node and atrioventricular ring, and the ventricles had ventricular muscles, His bundle, bundle branches, and Purkinje network. The epicardial and endocardial myofiber orientations of the ventricles and one layer of atrial myofiber orientation were then measured. They were calculated using linear interpolation technique and minimum distance algorithm, respectively. To the best of our knowledge, this is the first anatomically-detailed human heart model with corresponding experimentally measured fibers orientation. In addition, the whole heart excitation propagation was simulated using a monodomain model. The simulated normal activation sequence agreed well with the published experimental findings.

  11. Factor Structure of the Group Engagement Measure

    ERIC Educational Resources Information Center

    Macgowan, Mark J.; Newman, Frederick L.

    2005-01-01

    The Group Engagement Measure (GEM) assesses a commonly used, but rarely measured, process in group work. Earlier studies examined the reliability and validity of the GEM, but none empirically examined its factor structure. The authors examined the seven-factor, 37-item structure of the GEM, using confirmatory factor analysis involving a combined…

  12. Copper TESLA structure: measurements and control

    NASA Astrophysics Data System (ADS)

    Główka, Jakub; Maciaś, Mateusz

    2008-01-01

    Phase and amplitude stabilization of accelerating field is a challenging task, which usually requires dedicated hardware and software. In this contribution, we introduce briefly parameters of an accelerating structure and basic measurements on the test stand with copper structure, helping to improve control systems required for stable operation of accelerating structures.

  13. Details of Resonant Structures within a Nice Model Kuiper Belt: Predictions for High-perihelion TNO Detections

    NASA Astrophysics Data System (ADS)

    Pike, R. E.; Lawler, S. M.

    2017-10-01

    We analyze a detailed Nice model simulation of Kuiper Belt emplacement from Brasser & Morbidelli, where Neptune undergoes a high-eccentricity phase and migrates outward. In this work, which follows from Pike et al., we specifically focus on the details of structures within Neptune’s mean-motion resonances and in the high-pericenter population of simulated trans-Neptunian objects (TNOs). We find several characteristics of these populations that should be observable in the distant solar system in future large-scale TNO surveys as a diagnostic of whether or not this mode of Neptune migration occurred in the early solar system. We find that the leading asymmetric libration islands of the n:1 resonances are generally much more populated than the trailing islands. We also find the nonresonant high-q population of TNOs should have higher inclinations than the low-q population due to the importance of Kozai cycling during their emplacement histories. Finally, high-q TNOs should be present in roughly equal numbers on either side of distant mean-motion resonances. These predictions contrast with predictions from other Kuiper Belt emplacement simulations and will be testable by upcoming surveys.

  14. Detailed characterization of a Comparative Reactivity Method (CRM) instrument for ambient OH reactivity measurements: experiments vs. modeling

    NASA Astrophysics Data System (ADS)

    Michoud, Vincent; Locoge, Nadine; Dusanter, Sébastien

    2015-04-01

    The Hydroxyl radical (OH) is the main daytime oxidant in the troposphere, leading to the oxidation of Volatile Organic Compounds (VOCs) and the formation of harmful pollutants such as ozone (O3) and Secondary Organic Aerosols (SOA). While OH plays a key role in tropospheric chemistry, recent studies have highlighted that there are still uncertainties associated with the OH budget, i.e the identification of sources and sinks and the quantification of production and loss rates of this radical. It has been demonstrated that ambient measurements of the total OH loss rate (also called total OH reactivity) can be used to identify and reduce these uncertainties. In this context, the Comparative Reactivity Method (CRM), developed by Sinha et al. (ACP, 2008), is a promising technique to measure total OH reactivity in ambient air and has already been used during several field campaigns. This technique relies on monitoring competitive reactions of OH with ambient trace gases and a reference compound (pyrrole) in a sampling reactor to derive ambient OH reactivity. However, this technique requires a complex data processing chain that has yet to be carefully investigated in the laboratory. In this study, we present a detailed characterization of a CRM instrument developed at Mines Douai, France. Experiments have been performed to investigate the dependence of the CRM response on humidity, ambient NOx levels, and the pyrrole-to-OH ratio inside the sampling reactor. Box modelling of the chemistry occurring in the reactor has also been performed to assess our theoretical understanding of the CRM measurement. This work shows that the CRM response is sensitive to both humidity and NOx, which can be accounted for during data processing using parameterizations depending on the pyrrole-to-OH ratio. The agreement observed between laboratory studies and model results suggests a good understanding of the chemistry occurring in the sampling reactor and gives confidence in the CRM

  15. Detailed mapping of reservoir structural geometry in detached, shortened fold belts, Ortega (Aptian-Albian) field area, Girardot basin, Colombia

    SciTech Connect

    Allen, G.D. )

    1990-05-01

    Discovery and development of oil fields in shortened compressional fold belts require recognition that the largest reservoirs occur in intermediate or third-order scale folds. Third-order folds generally are preserved in the footwall of larger scale fold thrusts, and may be concealed beneath smaller, detached surface folds of nonreservoir condition. A successful reservoir mapping procedure involved (1) detailed surface mapping, (2) depth conversion of seismic data (3) construction of a network of true-scale balanced cross sections, and (4) contour mapping above and below the major zones of detachment. Structure at the 11 million bbl Ortega field consist of convergent third-order fold thrusts, with internal decollement. Tight flexural-slip folds imbricate and tectonically thicken upward on the west-verging Ortega anticline. The buried, east-vergent Salado anticline acts as a buttress to westward propagation at Ortega but retreats along strike to allow the Porvenir anticline to develop a low, broad, fault-bend fold geometry. At least four fault blocks in the Ortega field remain untested because balanced section analysis has not been employed to create additional control points for structure contour maps on the top of the reservoir. It is speculated that another 10-50 million bbl of primary recoverable reserves remain in the Ortega field. In addition, reservoirs like the Ortega field should occur elsewhere in the Girardot basin. These reservoirs likely will occur all along the footwall of fold-thrust structures on the flank of the intrabasin Pata high.

  16. A detailed Raman and X-ray study of UO2+x oxides and related structure transitions.

    PubMed

    Elorrieta, J M; Bonales, L J; Rodríguez-Villagra, N; Baonza, V G; Cobos, J

    2016-10-12

    This work presents a detailed study of hyperstoichiometric UO2+x (0 < x < 0.25) oxides and an assessment of the structural evolution taking place as oxidation proceeds. For this purpose, different UO2+x powder samples with controlled degree of non-stoichiometry have been identified by thermogravimetric analysis and characterized by X-ray diffraction (XRD) and Raman spectroscopy. XRD analysis reflects that the commonly assumed Vegard's law is not applicable over the whole hyperstoichiometry range, since a slight increase of the lattice constant is observed for 0.13 < x < 0.20. A quantitative Raman analysis of the UO2+x spectra as a function of the oxidation degree is also shown. A new method to characterize any UO2+x sample (for x < 0.20), based on the shift of the 630 cm(-1) band observed in the Raman spectrum, is proposed here for the first time. Moreover, three structure transitions have been detected at x = 0.05, 0.11 and 0.20, giving rise to four distinct regions associated with consecutive structural rearrangements over the hyperstoichiometry range: x < 0.05, 0.05 < x < 0.11, 0.11 < x < 0.20 and 0.20 < x < 0.25.

  17. Coupling a distributed hydrological model with detailed forest structural information for large-scale global change impact assessment

    NASA Astrophysics Data System (ADS)

    Eisner, Stephanie; Huang, Shaochun; Majasalmi, Titta; Bright, Ryan; Astrup, Rasmus; Beldring, Stein

    2017-04-01

    Forests are recognized for their decisive effect on landscape water balance with structural forest characteristics as stand density or species composition determining energy partitioning and dominant flow paths. However, spatial and temporal variability in forest structure is often poorly represented in hydrological modeling frameworks, in particular in regional to large scale hydrological modeling and impact analysis. As a common practice, prescribed land cover classes (including different generic forest types) are linked to parameter values derived from literature, or parameters are determined by calibration. While national forest inventory (NFI) data provide comprehensive, detailed information on hydrologically relevant forest characteristics, their potential to inform hydrological simulation over larger spatial domains is rarely exploited. In this study we present a modeling framework that couples the distributed hydrological model HBV with forest structural information derived from the Norwegian NFI and multi-source remote sensing data. The modeling framework, set up for the entire of continental Norway at 1 km spatial resolution, is explicitly designed to study the combined and isolated impacts of climate change, forest management and land use change on hydrological fluxes. We use a forest classification system based on forest structure rather than biomes which allows to implicitly account for impacts of forest management on forest structural attributes. In the hydrological model, different forest classes are represented by three parameters: leaf area index (LAI), mean tree height and surface albedo. Seasonal cycles of LAI and surface albedo are dynamically simulated to make the framework applicable under climate change conditions. Based on a hindcast for the pilot regions Nord-Trøndelag and Sør-Trøndelag, we show how forest management has affected regional hydrological fluxes during the second half of the 20th century as contrasted to climate variability.

  18. Understanding the structure of skill through a detailed analysis of Individuals' performance on the Space Fortress game.

    PubMed

    Towne, Tyler J; Boot, Walter R; Ericsson, K Anders

    2016-09-01

    In this paper we describe a novel approach to the study of individual differences in acquired skilled performance in complex laboratory tasks based on an extension of the methodology of the expert-performance approach (Ericsson & Smith, 1991) to shorter periods of training and practice. In contrast to more traditional approaches that study the average performance of groups of participants, we explored detailed behavioral changes for individual participants across their development on the Space Fortress game. We focused on dramatic individual differences in learning and skill acquisition at the individual level by analyzing the archival game data of several interesting players to uncover the specific structure of their acquired skill. Our analysis revealed that even after maximal values for game-generated subscores were reached, the most skilled participant's behaviors such as his flight path, missile firing, and mine handling continued to be refined and improved (Participant 17 from Boot et al., 2010). We contrasted this participant's behavior with the behavior of several other participants and found striking differences in the structure of their performance, which calls into question the appropriateness of averaging their data. For example, some participants engaged in different control strategies such as "world wrapping" or maintaining a finely-tuned circular flight path around the fortress (in contrast to Participant 17's angular flight path). In light of these differences, we raise fundamental questions about how skill acquisition for individual participants should be studied and described. Our data suggest that a detailed analysis of individuals' data is an essential step for generating a general theory of skill acquisition that explains improvement at the group and individual levels.

  19. Accelerator Structure Bead Pull Measurement at SLAC

    SciTech Connect

    Lewandowski, J.R.; Bowden, G.; Miller, R.H.; Wang, J.W.; /SLAC

    2005-05-13

    Microwave measurement and tuning of accelerator structures are important issues for the current and next generation of high energy physics machines. Application of these measurements both before and after high power processing can reveal information about the structure but may be misinterpreted if measurement conditions are not carefully controlled. For this reason extensive studies to characterize the microwave measurements have been made at SLAC. For the bead pull a reproducible measurement of less than 1 degree of phase accuracy in total phase drift is needed in order to resolve issues such as phase changes due to structure damage during high power testing. Factors contributing to measurement errors include temperature drift, mechanical vibration, and limitations of measurement equipment such as the network analyzer. Results of this continuing effort will be presented.

  20. Detailed off-gas measurements for improved modelling of the aeration performance at the WWTP of Eindhoven.

    PubMed

    Amerlinck, Y; Bellandi, G; Amaral, A; Weijers, S; Nopens, I

    2016-01-01

    At wastewater treatment plants (WWTPs), the aerobic conversion processes in the bioreactor are driven by the presence of dissolved oxygen (DO). Within these conversion processes, the oxygen transfer is a rate limiting step as well as being the largest energy consumer. Despite this high importance, WWTP models often lack detail on the aeration part. An extensive measurement campaign with off-gas tests was performed at the WWTP of Eindhoven to provide more information on the performance and behaviour of the aeration system. A high spatial and temporal variability in the oxygen transfer efficiency was observed. Applying this gathered system knowledge in the aeration model resulted in an improved prediction of the DO concentrations. Moreover, an important consequence of this was that ammonium predictions could be improved by resetting the ammonium half-saturation index for autotrophs to its default value. This again proves the importance of balancing sub-models with respect to the need for model calibration as well as model predictive power.

  1. Validation of Monte Carlo simulation of mammography with TLD measurement and depth dose calculation with a detailed breast model

    NASA Astrophysics Data System (ADS)

    Wang, Wenjing; Qiu, Rui; Ren, Li; Liu, Huan; Wu, Zhen; Li, Chunyan; Li, Junli

    2017-09-01

    Mean glandular dose (MGD) is not only determined by the compressed breast thickness (CBT) and the glandular content, but also by the distribution of glandular tissues in breast. Depth dose inside the breast in mammography has been widely concerned as glandular dose decreases rapidly with increasing depth. In this study, an experiment using thermo luminescent dosimeters (TLDs) was carried out to validate Monte Carlo simulations of mammography. Percent depth doses (PDDs) at different depth values were measured inside simple breast phantoms of different thicknesses. The experimental values were well consistent with the values calculated by Geant4. Then a detailed breast model with a CBT of 4 cm and a glandular content of 50%, which has been constructed in previous work, was used to study the effects of the distribution of glandular tissues in breast with Geant4. The breast model was reversed in direction of compression to get a reverse model with a different distribution of glandular tissues. Depth dose distributions and glandular tissue dose conversion coefficients were calculated. It revealed that the conversion coefficients were about 10% larger when the breast model was reversed, for glandular tissues in the reverse model are concentrated in the upper part of the model.

  2. Strategies and Techniques Measuring Historical Channel Change by Integrating Spatially-Robust Data with Detailed Site Measurements, Green River and Colorado River in Grand Canyon

    NASA Astrophysics Data System (ADS)

    Grams, P. E.; Schmidt, J. C.

    2001-12-01

    Analysis of river channel change and calculation of sediment budgets demands integration of detailed but spatially-limited topographic and stratigraphic data with spatially-robust, but temporally-limited, aerial photograph data. Geomorphologists typically rely on analysis of aerial photographs to assess channel change, because photos are widely available and provide spatially rich data. But air photos present several challenges: (1) aerial photos provide limited detail relative to ground-based measurements and historical aerial photos can be even more difficult to use, having shadows or poor resolution; (2) photos have poor temporal resolution and historical data are often limited to one flight per decade; and (3) long-term trends can be difficult to identify if there is high within-reach variability. We present several methods that we have used to integrate spatially-robust mapping from aerial photos with detailed site measurements and observations to develop robust analyses of channel change for over 400 km of the Green River in Utah and Colorado and for approximately 100 km of the Colorado River in Glen, Marble, and Grand Canyons. We improve the precision of our analyses by integrating aerial photo-based mapping with ground surveys, channel cross-section measurements, and historical oblique photos. We improve our temporal resolution by integrating aerial photo-based mapping with USGS gage station records. In the case of the Colorado River in Grand Canyon, we address the problems of variability by applying analyses and statistical methods that take advantage of the unique characteristics of eddy sand bars. Because sand bars do not migrate in reaches with fan-eddy complexes, the total extent of possible sediment storage in eddies can be objectively defined, allowing the derivation of metrics that describe the reach-average sediment storage condition for comparison with other reaches and other times. In alluvial reaches, we rely on analysis of temporally-detailed

  3. Dynamism & Detail

    ERIC Educational Resources Information Center

    Flannery, Maura C.

    2004-01-01

    New material discovered in the study of cell research is presented for the benefit of biology teachers. Huge amounts of data are being generated in fields like cellular dynamics, and it is felt that people's understanding of the cell is becoming much more complex and detailed.

  4. Dynamism & Detail

    ERIC Educational Resources Information Center

    Flannery, Maura C.

    2004-01-01

    New material discovered in the study of cell research is presented for the benefit of biology teachers. Huge amounts of data are being generated in fields like cellular dynamics, and it is felt that people's understanding of the cell is becoming much more complex and detailed.

  5. Structurally detailed coarse-grained model for Sec-facilitated co-translational protein translocation and membrane integration

    PubMed Central

    Miller, Thomas F.

    2017-01-01

    We present a coarse-grained simulation model that is capable of simulating the minute-timescale dynamics of protein translocation and membrane integration via the Sec translocon, while retaining sufficient chemical and structural detail to capture many of the sequence-specific interactions that drive these processes. The model includes accurate geometric representations of the ribosome and Sec translocon, obtained directly from experimental structures, and interactions parameterized from nearly 200 μs of residue-based coarse-grained molecular dynamics simulations. A protocol for mapping amino-acid sequences to coarse-grained beads enables the direct simulation of trajectories for the co-translational insertion of arbitrary polypeptide sequences into the Sec translocon. The model reproduces experimentally observed features of membrane protein integration, including the efficiency with which polypeptide domains integrate into the membrane, the variation in integration efficiency upon single amino-acid mutations, and the orientation of transmembrane domains. The central advantage of the model is that it connects sequence-level protein features to biological observables and timescales, enabling direct simulation for the mechanistic analysis of co-translational integration and for the engineering of membrane proteins with enhanced membrane integration efficiency. PMID:28328943

  6. Antifreeze (glyco)protein mimetic behavior of poly(vinyl alcohol): detailed structure ice recrystallization inhibition activity study.

    PubMed

    Congdon, Thomas; Notman, Rebecca; Gibson, Matthew I

    2013-05-13

    This manuscript reports a detailed study on the ability of poly(vinyl alcohol) to act as a biomimetic surrogate for antifreeze(glyco)proteins, with a focus on the specific property of ice-recrystallization inhibition (IRI). Despite over 40 years of study, the underlying mechanisms that govern the action of biological antifreezes are still poorly understood, which is in part due to their limited availability and challenging synthesis. Poly(vinyl alcohol) (PVA) has been shown to display remarkable ice recrystallization inhibition activity despite its major structural differences to native antifreeze proteins. Here, controlled radical polymerization is used to synthesize well-defined PVA, which has enabled us to obtain the first quantitative structure-activity relationships, to probe the role of molecular weight and comonomers on IRI activity. Crucially, it was found that IRI activity is "switched on" when the polymer chain length increases from 10 and 20 repeat units. Substitution of the polymer side chains with hydrophilic or hydrophobic units was found to diminish activity. Hydrophobic modifications to the backbone were slightly more tolerated than side chain modifications, which implies an unbroken sequence of hydroxyl units is necessary for activity. These results highlight that, although hydrophobic domains are key components of IRI activity, the random inclusion of addition hydrophobic units does not guarantee an increase in activity and that the actual polymer conformation is important.

  7. Structural health monitoring using piezoelectric impedance measurements.

    PubMed

    Park, Gyuhae; Inman, Daniel J

    2007-02-15

    This paper presents an overview and recent advances in impedance-based structural health monitoring. The basic principle behind this technique is to apply high-frequency structural excitations (typically greater than 30kHz) through surface-bonded piezoelectric transducers, and measure the impedance of structures by monitoring the current and voltage applied to the piezoelectric transducers. Changes in impedance indicate changes in the structure, which in turn can indicate that damage has occurred. An experimental study is presented to demonstrate how this technique can be used to detect structural damage in real time. Signal processing methods that address damage classifications and data compression issues associated with the use of the impedance methods are also summarized. Finally, a modified frequency-domain autoregressive model with exogenous inputs (ARX) is described. The frequency-domain ARX model, constructed by measured impedance data, is used to diagnose structural damage with levels of statistical confidence.

  8. Some experiments in swirling flows: Detailed velocity measurements of a vortex breakdown using a laser Doppler anemometer. Ph.D. Thesis - Cornell Univ. Final Report

    NASA Technical Reports Server (NTRS)

    Faler, J. H.

    1976-01-01

    The results of an experimental study of spiraling flows in a slightly diverging, circular duct are reported. Seven types of flow disturbances were observed. In addition to the spiral and axisymmetric vortex breakdowns and the double helix mode, four other forms were identified and are reported. The type and axial location of the disturbance depended on the Reynolds and circulation numbers of the flow. Detailed velocity measurements were made by using a laser Doppler anemometer. Measurements made far upstream of any disturbance showed that the introduction of swirl resulted in the formation of a high axial velocity jet centered around the vortex center. A mapping of the velocity field of a so-called axisymmetric breakdown, formed at a Reynolds number of 2560, revealed that the recirculation zone is a two-celled structure, with four stagnation points on the vortex axis marking the axial extremes of the concentric cells. The dominant feature of the flow inside the bubble was the strong, periodic velocity fluctuations. Existing theoretical models do not predict the two-celled structure and the temporal velocity fluctuations that were observed.

  9. Structural Integrity in Measures of Self Concept.

    ERIC Educational Resources Information Center

    Stenner, A. Jackson; Katzenmeyer, W.G.

    Structural integrity of a measure is defined in terms of its replicability, constancy, invariance, and stability. Work completed in the development and validation of the Self Observation Scales (SOS) Primary Level (Stenner and Katzenmeyer, 1973) serves to illustrate one method of establishing structural integrity. The name of each scale of the SOS…

  10. Detailed Structural Characterization of Sphingolipids via 193 nm Ultraviolet Photodissociation and Ultra High Resolution Tandem Mass Spectrometry

    NASA Astrophysics Data System (ADS)

    Ryan, Eileen; Nguyen, Catherine Quynh Nhu; Shiea, Christopher; Reid, Gavin E.

    2017-07-01

    Sphingolipids serve not only as components of cellular membranes but also as bioactive mediators of numerous cellular functions. As the biological activities of these lipids are dependent on their structures, and due to the limitations of conventional ion activation methods employed during tandem mass spectrometry (MS/MS), there is a recognized need for the development of improved structure-specific methods for their comprehensive identification and characterization. Here, positive-ionization mode 193 nm ultraviolet photodissociation (UVPD)-MS/MS has been implemented for the detailed structural characterization of lipid species from a range of sphingolipid classes introduced to the mass spectrometer via electrospray ionization as their lithiated or protonated adducts. These include sphingosine d18:1(4E), dihydrosphingosine (sphinganine) d18:0, sphingadiene d18:2(4E,11Z), the isomeric sphingolipids ceramide d18:1(4E)/18:0 and dihydroceramide d18:0/18:1(9Z), ceramide-1-phosphate d18:1(4Z)/16:0, sphingomyelin d18:1(4E)/18:1(9Z) the glycosphingolipids galactosyl ceramide d18:1(4E)/24:1(15Z) and lactosyl ceramide d18:1(4E)/24:0, and several endogenous lipids present within a porcine brain total lipid extract. In addition to the product ions formed by higher energy collision dissociation (HCD), UVPD is shown to yield a series of novel structurally diagnostic product ions resulting from cleavage of both sphingosine carbon-carbon and acyl chain carbon-carbon double bonds for direct localization of site(s) of unsaturation, as well as via diagnostic cleavages of the sphingosine backbone and N-C amide bond linkages. With activation timescales and dissociation efficiencies similar to those found in conventional MS/MS strategies, this approach is therefore a promising new tool in the arsenal of ion activation techniques toward providing complete structural elucidation in automated, high-throughput lipid analysis workflows.

  11. Advanced structural analysis of nanoporous materials by thermal response measurements.

    PubMed

    Oschatz, Martin; Leistner, Matthias; Nickel, Winfried; Kaskel, Stefan

    2015-04-07

    Thermal response measurements based on optical adsorption calorimetry are presented as a versatile tool for the time-saving and profound characterization of the pore structure of porous carbon-based materials. This technique measures the time-resolved temperature change of an adsorbent during adsorption of a test gas. Six carbide and carbon materials with well-defined nanopore architecture including micro- and/or mesopores are characterized by thermal response measurements based on n-butane and carbon dioxide as the test gases. With this tool, the pore systems of the model materials can be clearly distinguished and accurately analyzed. The obtained calorimetric data are correlated with the adsorption/desorption isotherms of the materials. The pore structures can be estimated from a single experiment due to different adsorption enthalpies/temperature increases in micro- and mesopores. Adsorption/desorption cycling of n-butane at 298 K/1 bar with increasing desorption time allows to determine the pore structure of the materials in more detail due to different equilibration times. Adsorption of the organic test gas at selected relative pressures reveals specific contributions of particular pore systems to the increase of the temperature of the samples and different adsorption mechanisms. The use of carbon dioxide as the test gas at 298 K/1 bar provides detailed insights into the ultramicropore structure of the materials because under these conditions the adsorption of this test gas is very sensitive to the presence of pores smaller than 0.7 nm.

  12. Detailed transient heme structures of Mb-CO in solution after CO dissociation: an X-ray transient absorption spectroscopic study.

    PubMed

    Stickrath, Andrew B; Mara, Michael W; Lockard, Jenny V; Harpham, Michael R; Huang, Jier; Zhang, Xiaoyi; Attenkofer, Klaus; Chen, Lin X

    2013-04-25

    Although understanding the structural dynamics associated with ligand photodissociation is necessary in order to correlate structure and function in biological systems, few techniques are capable of measuring the ultrafast dynamics of these systems in solution-phase at room temperature. We present here a detailed X-ray transient absorption (XTA) study of the photodissociation of CO-bound myoglobin (Fe(II)CO-Mb) in room-temperature aqueous buffer solution with a time resolution of 80 ps, along with a general procedure for handling biological samples under the harsh experimental conditions that transient X-ray experiments entail. The XTA spectra of (Fe(II)CO-Mb) exhibit significant XANES and XAFS alterations following 527 nm excitation, which remain unchanged for >47 μs. These spectral changes indicate loss of the CO ligand, resulting in a five-coordinate, domed heme, and significant energetic reorganization of the 3d orbitals of the Fe center. With the current experimental setup, each X-ray pulse in the pulse train, separated by ~153 ns, can be separately discriminated, yielding snapshots of the myoglobin evolution over time. These methods can be easily applied to other biological systems, allowing for simultaneous structural and electronic measurements of any biological system with both ultrafast and slow time resolutions, effectively mapping out all of the samples' relevant physiological processes.

  13. Attenuation tomography in the western central Andes: A detailed insight into the structure of a magmatic arc

    NASA Astrophysics Data System (ADS)

    Haberland, Christian; Rietbrock, Andreas

    2001-06-01

    High-quality data from 1498 local earthquakes recorded by the PISCO '94 (Proyecto de Investigatión Sismológica de la Cordillera Occidental, 1994) and ANCORP '96 (Andean Continental Research Project, 1996) temporary seismological networks allowed the detailed determination of the three-dimensional (3-D) attenuation structure (Qp-1) beneath the recent magmatic arc in the western central Andes (20° to 24°S). Assuming a frequency-independent Qp-1 in a frequency band between 1 and 30 Hz, whole path attenuation (t*) was estimated from the amplitude spectra of the P waves using spectral ratios and a spectral inversion technique. The damped least squares inversion (tomography) of the data reveals a complex attenuation structure. Crust and mantle of the forearc and subducting slab are generally characterized by low attenuation (Qp > 1000). Crust and mantle beneath the magmatic arc show elevated attenuation. The strongest anomaly of extremely low Qp is found in the crust between 22° and 23°S beneath the recent volcanic arc (Qp < 100). N-S variations can be observed: The western flank of the crustal attenuation anomaly follows the curved course of the volcanic front. North of 21°S the attenuation is less developed. In the northern part of the study area the low-Qp zone penetrates in the forearc mantle down to the subducting slab. In the south a deeper zone of high attenuation is resolved between 23° and 24°S directly above the subducting slab. Low Qp in the mantle correlates with earthquake clusters. The strong crustal attenuation is confined to the distribution of young ignimbrites and silicic volcanism and is interpreted as a thermally weakened zone with partial melts. The attenuation pattern in the upper mantle might reflect the variable extent of the asthenosphere and maps variations of subduction-related hydration processes in the mantle wedge from slab-derived fluids.

  14. A survey of molecular details in the human pineal gland in the light of phylogeny, structure, function and chronobiological diseases.

    PubMed

    Stehle, Jörg H; Saade, Anastasia; Rawashdeh, Oliver; Ackermann, Katrin; Jilg, Antje; Sebestény, Tamás; Maronde, Erik

    2011-08-01

    The human pineal gland is a neuroendocrine transducer that forms an integral part of the brain. Through the nocturnally elevated synthesis and release of the neurohormone melatonin, the pineal gland encodes and disseminates information on circadian time, thus coupling the outside world to the biochemical and physiological internal demands of the body. Approaches to better understand molecular details behind the rhythmic signalling in the human pineal gland are limited but implicitly warranted, as human chronobiological dysfunctions are often associated with alterations in melatonin synthesis. Current knowledge on melatonin synthesis in the human pineal gland is based on minimally invasive analyses, and by the comparison of signalling events between different vertebrate species, with emphasis put on data acquired in sheep and other primates. Together with investigations using autoptic pineal tissue, a remnant silhouette of premortem dynamics within the hormone's biosynthesis pathway can be constructed. The detected biochemical scenario behind the generation of dynamics in melatonin synthesis positions the human pineal gland surprisingly isolated. In this neuroendocrine brain structure, protein-protein interactions and nucleo-cytoplasmic protein shuttling indicate furthermore a novel twist in the molecular dynamics in the cells of this neuroendocrine brain structure. These findings have to be seen in the light that an impaired melatonin synthesis is observed in elderly and/or demented patients, in individuals affected by Alzheimer's disease, Smith-Magenis syndrome, autism spectrum disorder and sleep phase disorders. Already, recent advances in understanding signalling dynamics in the human pineal gland have significantly helped to counteract chronobiological dysfunctions through a proper restoration of the nocturnal melatonin surge.

  15. Academic detailing.

    PubMed

    Shankar, P R; Jha, N; Piryani, R M; Bajracharya, O; Shrestha, R; Thapa, H S

    2010-01-01

    There are a number of sources available to prescribers to stay up to date about medicines. Prescribers in rural areas in developing countries however, may not able to access some of them. Interventions to improve prescribing can be educational, managerial, and regulatory or use a mix of strategies. Detailing by the pharmaceutical industry is widespread. Academic detailing (AD) has been classically seen as a form of continuing medical education in which a trained health professional such as a physician or pharmacist visits physicians in their offices to provide evidence-based information. Face-to-face sessions, preferably on an individual basis, clear educational and behavioural objectives, establishing credibility with respect to objectivity, stimulating physician interaction, use of concise graphic educational materials, highlighting key messages, and when possible, providing positive reinforcement of improved practices in follow-up visits can increase success of AD initiatives. AD is common in developed countries and certain examples have been cited in this review. In developing countries the authors have come across reports of AD in Pakistan, Sudan, Argentina and Uruguay, Bihar state in India, Zambia, Cuba, Indonesia and Mexico. AD had a consistent, small but potentially significant impact on prescribing practices. AD has much less resources at its command compared to the efforts by the industry. Steps have to be taken to formally start AD in Nepal and there may be specific hindering factors similar to those in other developing nations.

  16. LASER BIOLOGY AND MEDICINE: Visualisation of details of a complicated inner structure of model objects by the method of diffusion optical tomography

    NASA Astrophysics Data System (ADS)

    Tret'yakov, Evgeniy V.; Shuvalov, Vladimir V.; Shutov, I. V.

    2002-11-01

    An approximate algorithm is tested for solving the problem of diffusion optical tomography in experiments on the visualisation of details of the inner structure of strongly scattering model objects containing scattering and semitransparent inclusions, as well as absorbing inclusions located inside other optical inhomogeneities. The stability of the algorithm to errors is demonstrated, which allows its use for a rapid (2 — 3 min) image reconstruction of the details of objects with a complicated inner structure.

  17. Measures of Complexity to quantify Bone Structure

    NASA Astrophysics Data System (ADS)

    Saparin, Peter; Gowin, Wolfgang; Kurths, Jürgen; Felsenberg, Dieter

    1998-03-01

    We propose a technique to assess structure of the bone in its spatial distribution by describing and quantifying the structural architecture as a whole. The concept of measures of complexity based on symbolic dynamics is applied to computed tomography (CT) - images obtained from human lumbar vertebra. CT-images have been transformed into images consisting of 5 different symbols, whereby both statical and dynamical coding are included. Different aspects of the bone structure are quantified by several measures which have been introduced: index of global ensemble of elements composing the bone; complexity, homogeneity and dynamics within the bone architecture; complexity and inhomogeneity of the trabecular net. This leads to new insides to the understanding of bone's internal structure. The results give the first experimental and quantitative evidence of the theoretical prediction that complexity of bone structure declines rapidly with the increased disintegration of bone structures leading to the loss of bone mass and specify experimentally that bone structure is exponentially related to its density. Especially, osteoporotic vertebrae are less complex organized than normal ones. In addition, this method is significantly sensitive to changes in bone structure and provides improvements of diagnostic of pathological structural loss.

  18. Crump Geyser Exploration and Drilling Project. High Precision Geophysics and Detailed Structural Exploration and Slim Well Drilling

    SciTech Connect

    Fairbank, Brian D.; Smith, Nicole

    2015-06-10

    The Crump Geyser Exploration and Drilling Project – High Precision Geophysics and Detailed Structural Exploration and Slim Well Drilling ran from January 29, 2010 to September 30, 2013. During Phase 1 of the project, collection of all geophysical surveys was completed as outlined in the Statement of Project Objectives. In addition, a 5000-foot full sized exploration well was drilled by Ormat, and preexisting drilling data was discovered for multiple temperature gradient wells within the project area. Three dimensional modeling and interpretation of results from the geophysical surveys and drilling data gave confidence to move to the project into Phase 2 drilling. Geological and geophysical survey interpretations combined with existing downhole temperature data provided an ideal target for the first slim-hole drilled as the first task in Phase 2. Slim-hole 35-34 was drilled in September 2011 and tested temperature, lithology, and permeability along the primary range-bounding fault zone near its intersection with buried northwest-trending faults that have been identified using geophysical methods. Following analysis of the results of the first slim-hole 35-34, the second slim hole was not drilled and subsequent project tasks, including flowing differential self-potential (FDSP) surveys that were designed to detail the affect of production and injection on water flow in the shallow aquifer, were not completed. NGP sold the Crump project to Ormat in August 2014, afterwards, there was insufficient time and interest from Ormat available to complete the project objectives. NGP was unable to continue managing the award for a project they did not own due to liability issues and Novation of the award was not a viable option due to federal award timelines. NGP submitted a request to mutually terminate the award on February 18, 2015. The results of all of the technical surveys and drilling are included in this report. Fault interpretations from surface geology, aeromag

  19. Input estimation from measured structural response

    SciTech Connect

    Harvey, Dustin; Cross, Elizabeth; Silva, Ramon A; Farrar, Charles R; Bement, Matt

    2009-01-01

    This report will focus on the estimation of unmeasured dynamic inputs to a structure given a numerical model of the structure and measured response acquired at discrete locations. While the estimation of inputs has not received as much attention historically as state estimation, there are many applications where an improved understanding of the immeasurable input to a structure is vital (e.g. validating temporally varying and spatially-varying load models for large structures such as buildings and ships). In this paper, the introduction contains a brief summary of previous input estimation studies. Next, an adjoint-based optimization method is used to estimate dynamic inputs to two experimental structures. The technique is evaluated in simulation and with experimental data both on a cantilever beam and on a three-story frame structure. The performance and limitations of the adjoint-based input estimation technique are discussed.

  20. On the structure and dynamics of Ellerman bombs. Detailed study of three events and modelling of Hα

    NASA Astrophysics Data System (ADS)

    Bello González, N.; Danilovic, S.; Kneer, F.

    2013-09-01

    Aims: We study the structure and dynamics of three Ellerman bombs (EBs) observed in an evolving active region. Methods: The active region NOAA 11271 was observed with the Vacuum Tower Telescope at Observatorio del Teide/Tenerife on August 18, 2011. We used the two-dimensional Triple Etalon SOlar Spectrometer (TESOS) to obtain time sequences of the active region and of EBs in Hα at a cadence of 15 s. Simultaneously, we obtained full Stokes profiles with the Tenerife Infrared Polarimeter (TIP II) in the two magnetically sensitive Fe i infrared lines (IR) at 1.56 μ, scanning spatial sections of the area with cadences of 28-46 s. The Hα data were reconstructed with speckle methods to study the evolution of the atmospheric stratification. Two methods were used to extract magnetic field information from the IR Stokes profiles: 1) fitting of the (Q,U,V) profiles by Gaussians; and 2) applying the Milne-Eddington approximation, assuming two separate magnetic structures in the resolution element and fitting by trial and error some profiles from the EB areas. Data from SDO-HMI and -AIA were also used. We performed two-dimensional (2D) non-LTE radiative transfer calculations of Hα in parameterised models of EBs. Results: The three EBs studied in detail occurred in a complex active region near sunspots. They were very bright with a factor of 1.5-2.8 brighter than the nearby area. They lived for 1/2 h and longer. They were related to broadband faculae, but the latter were not the brightest features in the field of view. The EBs occurred in magnetic field configurations with opposite polarity close together. One EB was located at the outskirts of a penumbra of a complex sunspot and showed repeated "flaring" in SDO-AIA data. Another was close to a strong field patch and moved into this during the end of its lifetime. The third EB showed clear changes of field structure during the time it was observed. We obtained from the 2D modelling that heating and increase in Hα opacity

  1. Assessing the Impact of Multi-Sensor Data Fusion on Command and Control Operations in the Halifax Class Frigate: Recommendations for Measures for Performance and Detailed Test Plan

    DTIC Science & Technology

    2002-02-01

    Recommendations for Measures of Performance and Detailed Test Plan. by: M.L. Matthews, R.D.G. Webb, A.R. Keeble Humansystems Incorporated® 111...and operational performance in the Halifax class operations room. The plan details an incremental approach to T&E that will generate reliable and...valid performance data for a range of critical tasks performed by the Ops Room team, with a general focus on the role of ORO. A series of data

  2. Differential Measurement Periodontal Structures Mapping System

    NASA Technical Reports Server (NTRS)

    Companion, John A. (Inventor)

    1998-01-01

    This invention relates to a periodontal structure mapping system employing a dental handpiece containing first and second acoustic sensors for locating the Cemento-Enamel Junction (CEJ) and measuring the differential depth between the CEJ and the bottom of the periodontal pocket. Measurements are taken at multiple locations on each tooth of a patient, observed, analyzed by an optical analysis subsystem, and archived by a data storage system for subsequent study and comparison with previous and subsequent measurements. Ultrasonic transducers for the first and second acoustic sensors are contained within the handpiece and in connection with a control computer. Pressurized water is provided for the depth measurement sensor and a linearly movable probe sensor serves as the sensor for the CEJ finder. The linear movement of the CEJ sensor is obtained by a control computer actuated by the prober. In an alternate embodiment, the CEJ probe is an optical fiber sensor with appropriate analysis structure provided therefor.

  3. COAXIAL WIRE MEASUREMENTS IN NLC ACCELERATING STRUCTURES

    SciTech Connect

    Jones, Roger M

    2002-06-20

    The coaxial wire method provides an experimental way of measuring wake fields without the need for a particle beam. A special setup has been designed and is in the process of being fabricated at SLAC to measure the loss factors and synchronous frequencies of dipole modes in both traveling and standing wave structures for the Next Linear Collider (NLC). The method is described and predictions based on electromagnetic field simulations are discussed.

  4. The Family Relationships Grid: Measuring Family Structure.

    ERIC Educational Resources Information Center

    Copeland, Anne P.; And Others

    This study examined the Family Relationships Grid (FRG), a new measure of family structure that evaluates alliances, identification, isolation, and the relative strength of sibling and marital relationships. Subjects were 52 female and 35 male adolescents who were recruited through a university course and who each had at least one sibling.…

  5. Th-substituted SmFeAsO: Structural details and superconductivity with Tc above 50 K

    NASA Astrophysics Data System (ADS)

    Zhigadlo, N. D.; Katrych, S.; Weyeneth, S.; Puzniak, R.; Moll, P. J. W.; Bukowski, Z.; Karpinski, J.; Keller, H.; Batlogg, B.

    2010-08-01

    We report structural, magnetic, and transport properties of polycrystalline samples and single crystals of superconducting Sm1-xThxFeAsO with maximal Tc above 50 K, prepared under high pressure. Bulk superconducting samples do not undergo a structural phase transition from tetragonal to orthorhombic symmetry at low temperatures. The unit-cell parameters a and c shrink with Th substitution and the fractional atomic coordinate of the As site zAs remains almost unchanged while that of Sm/Th zSm/Th increases. Upon warming from 5 to 295 K the increase in the FeAs layer thickness is dominant, while the changes in the other structural building blocks are minor, and they compensate each other, since the As-Sm/Th distance contracts by about the same amount as the O-Sm/Th expands. The polycrystalline and single-crystalline samples are characterized by a full diamagnetic response in low magnetic field, by a high intergrain critical current density for polycrystalline samples, and by a critical current density on the order of 8×105A/cm2 for single crystals at 2 K in fields up to 7 T. The magnetic penetration depth anisotropy γλ increases with decreasing temperature, in a similar way to that of SmFeAsO1-xFy single crystals. The upper critical field estimated from resistance measurements is anisotropic with slopes of ˜5.4T/K ( H∥ab plane) and ˜2.7T/K ( H∥c axis), at temperatures sufficiently far below Tc . The low-temperature upper critical field anisotropy γH is in the range of ˜2 , consistent with the tendency of a decreasing γH with decreasing temperature, previously reported for SmFeAsO1-xFy single crystals.

  6. Herschel far-infrared observations of the Carina Nebula complex. III. Detailed cloud structure and feedback effects

    NASA Astrophysics Data System (ADS)

    Roccatagliata, V.; Preibisch, T.; Ratzka, T.; Gaczkowski, B.

    2013-06-01

    Context. The star formation process in large clusters/associations can be strongly influenced by the feedback from high-mass stars. Whether the resulting net effect of the feedback is predominantly negative (cloud dispersal) or positive (triggering of star formation due to cloud compression) is still an open question. Aims: The Carina Nebula complex (CNC) represents one of the most massive star-forming regions in our Galaxy. We use our Herschel far-infrared observations to study the properties of the clouds over the entire area of the CNC (with a diameter of ≈3.2°, which corresponds to ≈125 pc at a distance of 2.3 kpc). The good angular resolution (10''-36'') of the Herschel maps corresponds to physical scales of 0.1-0.4 pc, and allows us to analyze the small-scale (i.e., clump-size) structures of the clouds. Methods: The full extent of the CNC was mapped with PACS and SPIRE in the 70, 160, 250, 350, and 500 μm bands. We determined temperatures and column densities at each point in these maps by modeling the observed far-infrared spectral energy distributions. We also derived a map showing the strength of the UV radiation field. We investigated the relation between the cloud properties and the spatial distribution of the high-mass stars and computed total cloud masses for different density thresholds. Results: Our Herschel maps resolve for the first time the small-scale structure of the dense clouds over the entire spatial extent of the CNC. Several particularly interesting regions, including the prominent pillars south of η Car, are analyzed in detail. We compare the cloud masses derived from the Herschel data with previous mass estimates based on sub-mm and molecular line data. Our maps also reveal a peculiar wave-like pattern in the northern part of the Carina Nebula. Finally, we characterize two prominent cloud complexes at the periphery of our Herschel maps, which are probably molecular clouds in the Galactic background. Conclusions: We find that the

  7. Structure of the full-length insecticidal protein Cry1Ac reveals intriguing details of toxin packaging into in vivo formed crystals

    PubMed Central

    Evdokimov, Artem G; Moshiri, Farhad; Sturman, Eric J; Rydel, Timothy J; Zheng, Meiying; Seale, Jeffrey W; Franklin, Sonya

    2014-01-01

    For almost half a century, the structure of the full-length Bacillus thuringiensis (Bt) insecticidal protein Cry1Ac has eluded researchers, since Bt-derived crystals were first characterized in 1965. Having finally solved this structure we report intriguing details of the lattice-based interactions between the toxic core of the protein and the protoxin domains. The structure provides concrete evidence for the function of the protoxin as an enhancer of native crystal packing and stability. PMID:25139047

  8. Investigation of detailed spatial structure of the Moscow urban heat island with application of the newest meteorological observations and regional climate modelling

    NASA Astrophysics Data System (ADS)

    Varentsov, Mikhail; Pavel, Konstantinov; Timofey, Samsonov

    2016-04-01

    During the last years, the network of metrological observation in Moscow megacity and its neighborhoods, forming the biggest urban agglomeration in Europe, was significantly extended. Several new weather stations and completely new dense network of air-quality monitoring appears during the last decade. In addition, several microwave meteorological profilers MTP 5, which are available to measure temperature at the heights from 0 to 1000 meters with 50-m resolution, were installed in the city and its surrounding. All these measurements allow revealing undiscovered features of Moscow urban climate and urban heat island (UHI). In our research, bases on this data, we covered several topics related to urban climatology: - Investigation of detailed spatial structure of Moscow UHI and its relationships with building features, such as land use and morphology of the street canyons, obtained by GIS-algorithms according (Samsonov et. al, 2015); - Investigation of three-dimensional structure of the UHI, including its vertical extend and influence on the stratification of the atmosphere, and three-dimensional structure of the urban heat island advection and urban heat plumes; - Application of the newest data for validation of the regional climate model COSMO-CLM, coupled with TEB urban scheme (Masson, 2000; Trusilova et. al., 2013), launched for Moscow region with 1-km spatial resolution. References: 1. Masson V. A. Physically-Based Scheme for the Urban Energy Budget in Atmospheric models. Bound. Layer Meteor. 2000. V. 94 (3). P. 357-397. 2. Trusilova K., Früh B., Brienen S., Walter A., Masson V., Pigeon G., Becker P. Implementation of an Urban Parameterization Scheme into the Regional Climate Model COSMO-CLM. J. Appl. Meteor. Climatol. V. 52. P. 2296-2311. 3. Samsonov T.E., Konstantinov P.I., Varentsov M.I. Object-oriented approach to urban canyon analysis and its applications in meteorological modeling. Urban Climate. 2015. Vol. 13. P. 122-139.

  9. A meta-structural understanding of measurement

    NASA Astrophysics Data System (ADS)

    Mari, Luca; Maul, Andrew; Torres Irribarra, David; Wilson, Mark

    2016-11-01

    It is not always clear to what extent the logic and vocabulary of measurement as used in different scientific disciplines are mutually coherent, nor how measurement can be demarcated from, say, opinion. In recent decades there have been a number of attempts to provide necessary and/or sufficient sets of conditions for when measurement is achieved, usually in terms either of inputs (e.g., whether an evaluated property is a quantity), or outputs (e.g., whether a procedure assigns numbers according to a rule). We argue instead that the public trust attributed to measurement is best justified in terms of the structural features of the process rather than of its inputs or outputs.

  10. Air Vehicle Integration and Technology Research (AVIATR). Delivery Order 0023: Predictive Capability for Hypersonic Structural Response and Life Prediction: Phase 2 - Detailed Design of Hypersonic Cruise Vehicle Hot-Structure

    DTIC Science & Technology

    2012-05-01

    AFRL-RQ-WP-TR-2012-0280 AIR VEHICLE INTEGRATION AND TECHNOLOGY RESEARCH (AVIATR) Delivery Order 0023: Predictive Capability for Hypersonic ...Structural Response and Life Prediction: Phase II - Detailed Design of Hypersonic Cruise Vehicle Hot-Structure Brian Zuchowski Lockheed Martin...Capability for Hypersonic Structural Response and Life Prediction: Phase II - Detailed Design of Hypersonic Cruise Vehicle Hot-Structure 5a. CONTRACT

  11. Structure in the Rotation Measure Sky

    NASA Astrophysics Data System (ADS)

    Stil, J. M.; Taylor, A. R.; Sunstrum, C.

    2011-01-01

    An analysis of structure in rotation measure (RM) across the sky based on the RM catalog of Taylor et al. is presented. Several resolved RM structures are identified with structure in the local interstellar medium, including radio loops I, II, and III, the Gum nebula, and the Orion-Eridanus superbubble. Structure functions (SFs) of RM are presented for selected areas, and maps of SF amplitude and slope across the sky are compared with Hα intensity and diffuse polarized intensity. RM variance on an angular scale of 1° is correlated with length of the line of sight through the Galaxy, with a contribution from local structures. The slope of the SFs is less concentrated to the Galactic plane and less correlated with length of the line of sight through the Galaxy, suggesting a more local origin for RM structure on angular scales ~10°. The RM variance is a factor of ~2 higher toward the South Galactic Pole than toward the North Galactic Pole, reflecting a more wide-spread asymmetry between the northern and southern Galactic hemispheres. Depolarization of diffuse Galactic synchrotron emission at latitudes <30° can be explained largely by Faraday dispersion related to small-scale variance in RM, but the errors allow a significant contribution from differential Faraday rotation along the line of sight.

  12. A dual resolution measurement based Monte Carlo simulation technique for detailed dose analysis of small volume organs in the skull base region

    NASA Astrophysics Data System (ADS)

    Yeh, Chi-Yuan; Tung, Chuan-Jung; Chao, Tsi-Chain; Lin, Mu-Han; Lee, Chung-Chi

    2014-11-01

    The purpose of this study was to examine dose distribution of a skull base tumor and surrounding critical structures in response to high dose intensity-modulated radiosurgery (IMRS) with Monte Carlo (MC) simulation using a dual resolution sandwich phantom. The measurement-based Monte Carlo (MBMC) method (Lin et al., 2009) was adopted for the study. The major components of the MBMC technique involve (1) the BEAMnrc code for beam transport through the treatment head of a Varian 21EX linear accelerator, (2) the DOSXYZnrc code for patient dose simulation and (3) an EPID-measured efficiency map which describes non-uniform fluence distribution of the IMRS treatment beam. For the simulated case, five isocentric 6 MV photon beams were designed to deliver a total dose of 1200 cGy in two fractions to the skull base tumor. A sandwich phantom for the MBMC simulation was created based on the patient's CT scan of a skull base tumor [gross tumor volume (GTV)=8.4 cm3] near the right 8th cranial nerve. The phantom, consisted of a 1.2-cm thick skull base region, had a voxel resolution of 0.05×0.05×0.1 cm3 and was sandwiched in between 0.05×0.05×0.3 cm3 slices of a head phantom. A coarser 0.2×0.2×0.3 cm3 single resolution (SR) phantom was also created for comparison with the sandwich phantom. A particle history of 3×108 for each beam was used for simulations of both the SR and the sandwich phantoms to achieve a statistical uncertainty of <2%. Our study showed that the planning target volume (PTV) receiving at least 95% of the prescribed dose (VPTV95) was 96.9%, 96.7% and 99.9% for the TPS, SR, and sandwich phantom, respectively. The maximum and mean doses to large organs such as the PTV, brain stem, and parotid gland for the TPS, SR and sandwich MC simulations did not show any significant difference; however, significant dose differences were observed for very small structures like the right 8th cranial nerve, right cochlea, right malleus and right semicircular canal. Dose

  13. Structural Loads Test Measurement Acquisition System (SLTMAS)

    NASA Technical Reports Server (NTRS)

    Patterson, Alan; Throckmorton, David A. (Technical Monitor)

    2001-01-01

    This presentation package, a PowerPoint presentation, will be presented at NASA's Sixteenth Annual Continual Improvement and Reinvention Conference as part of an Agency level competition highlighting continual improvements within NASA. The presentation provides a brief overview of the process used to improve the Structural and Dynamics Testing Group's data acquisition capabilities. Results measuring the success of the improvement cycle for the PC based SLTMAS will be presented.

  14. Nearly complete rRNA genes from 371 Animalia: updated structure-based alignment and detailed phylogenetic analysis.

    PubMed

    Mallatt, Jon; Craig, Catherine Waggoner; Yoder, Matthew J

    2012-09-01

    This study presents a manually constructed alignment of nearly complete rRNA genes from most animal clades (371 taxa from ~33 of the ~36 metazoan phyla), expanded from the 197 sequences in a previous study. This thorough, taxon-rich alignment, available at http://www.wsu.edu/~jmallatt/research/rRNAalignment.html and in the Dryad Repository (doi: http://dx.doi.org/10.5061/dryad.1v62kr3q), is based rigidly on the secondary structure of the SSU and LSU rRNA molecules, and is annotated in detail, including labeling of the erroneous sequences (contaminants). The alignment can be used for future studies of the molecular evolution of rRNA. Here, we use it to explore if the larger number of sequences produces an improved phylogenetic tree of animal relationships. Disappointingly, the resolution did not improve, neither when the standard maximum-likelihood method was used, nor with more sophisticated methods that partitioned the rRNA into paired and unpaired sites (stem, loop, bulge, junction), or accounted for the evolution of the paired sites. For example, no doublet model of paired-site substitutions (16-state, 16A and 16B, 7A-F, or 6A-C models) corrected the placement of any rogue taxa or increased resolution. The following findings are from the simplest, standard, ML analysis. The 371-taxon tree only imperfectly supported the bilaterian clades of Lophotrochozoa and Ecdysozoa, and this problem remained after 17 taxa with unstably positioned sequences were omitted from the analysis. The problem seems to stem from base-compositional heterogeneity across taxa and from an overrepresentation of highly divergent sequences among the newly added taxa (e.g., sequences from Cephalopoda, Rotifera, Acoela, and Myxozoa). The rogue taxa continue to concentrate in two locations in the rRNA tree: near the base of Arthropoda and of Bilateria. The approximately uncertain (AU) test refuted the monophyly of Mollusca and of Chordata, probably due to long-branch attraction of the highly

  15. Detailed histological structure of human hair follicle bulge region at different ages: a visible niche for nesting adult stem cells.

    PubMed

    Wang, Xiong; Shi, Ying; Zhou, Qiong; Liu, Xiaoming; Xu, Shizheng; Lei, Tiechi

    2012-10-01

    In the bulge region of the hair follicle, a densely and concentrically packed cell mass is encircled by the arrector pili muscle (APM), which offers a specilized microenvironment (niche) for housing heterogeneous adult stem cells. However, the detailed histological architecture and the cellular composition of the bulge region warrants intensive study and may have implications for the regulation of hair follicle growth regulation. This study was designed to define the gene-expression profiles of putative stem cells and lineage-specific precursors in the mid-portions of plucked hair follicles prepared according to the presence of detectable autofluorescence. The structure was also characterized by using a consecutive sectioning technique. The bulge region of the hair follicle with autofluorescence was precisely excised by employing a micro-dissection procedure. Semi-quantitative reverse transcription polymerase chain reaction (RT-PCR) was performed to identify the gene expression profiles specific for epithelial, melanocyte and stromal stem cells in the bulge region of the hair follicle visualized by autofluorescence. The morphology and its age-dependent changes of bulge region of the hair follicles with autofluorescence segment were also examined in 9 scalp skin specimens collected from patients aged 30 weeks to 75 years, by serial sectioning and immuno-staining. Gene expression profile analysis revealed that there were cells with mRNA transcripts of Dct(Hi)Tyrase(Lo)-Tyrp1(Lo)MC1R(Lo)MITF(Lo)/K15(Hi)/NPNT(Hi) in the bulge region of the hair follicle with autofluorescence segments, which differed from the patterns in hair bulbs. Small cell-protrusions that sprouted from the outer root sheath (ORS) were clearly observed at the APM inserting level in serial sections of hair follicles by immunohistological staining, which were characteristically replete with K15+/K19+expressing cells. Likewise, the muscle bundles of APM positive for smooth muscle actin intimately

  16. Measuring Structural Parameters Through Stacking Galaxy Images

    NASA Astrophysics Data System (ADS)

    Li, Yubin; Zheng, Xian Zhong; Gu, Qiu-Sheng; Wang, Yi-Peng; Wen, Zhang Zheng; Guo, Kexin; An, Fang Xia

    2016-12-01

    It remains challenging to detect the low surface brightness structures of faint high-z galaxies, which are key to understanding the structural evolution of galaxies. The technique of image stacking allows us to measure the averaged light profile beneath the detection limit and probe the extended structure of a group of galaxies. We carry out simulations to examine the recovery of the averaged surface brightness profile through stacking model Hubble Space Telescope/Advanced Camera for Surveys images of a set of galaxies as functions of the Sérsic index (n), effective radius (R e) and axis ratio (AR). The Sérsic profile best fitting the radial profile of the stacked image is taken as the recovered profile, in comparison with the intrinsic mean profile of the model galaxies. Our results show that, in general, the structural parameters of the mean profile can be properly determined through stacking, though systematic biases need to be corrected when spreads of R e and AR are counted. We find that the Sérsic index is slightly overestimated and R e is underestimated at {AR}\\lt 0.5 because the stacked image appears to be more compact due to the presence of inclined galaxies; the spread of R e biases the stacked profile to have a higher Sérsic index. We stress that the measurements of structural parameters through stacking should take these biases into account. We estimate the biases in the recovered structural parameters from stacks of galaxies when the samples have distributions of {R}{{e}}, AR and n seen in local galaxies.

  17. Measurements of the Ice Water Content of Cirrus in the Tropics and Subtropics. I; Instrument Details and Validation

    NASA Technical Reports Server (NTRS)

    Weinstock, E. M.; Smith, J. B.; Sayres, D.; Pittman, J. V.; Allen, N.; Demusz, J.; Greenberg, M.; Rivero, M.; Anderson, J. G.

    2003-01-01

    We describe an instrument mounted in a pallet on the NASA WB-57 aircraft that is designed to measure the sum of gas phase and solid phase water, or total water, in cirrus clouds. Using an isokinetic inlet, a 600-watt heater mounted directly in the flow, and Lyman-alpha photofragment fluorescence technique for detection, accurate measurements of total water have been made over almost three orders of magnitude. Isokinetic flow is achieved with an actively controlled roots pump by referencing aircraft pressure, temperature, and true air speed, together with instrument flow velocity, temperature, and pressure. During CRYSTAL FACE, the instrument operated at duct temperatures sufficiently warm to completely evaporate particles up to 150 microns diameter. In flight diagnostics, intercomparison with water measured by absorption in flight, as well as intercomparisons in clear air with water vapor measured by the Harvard water vapor instrument and the JPL infrared tunable diode laser hygrometer validate the detection sensitivity of the instrument and illustrate minimal hysteresis from instrument surfaces. The simultaneous measurement of total water and water vapor in cirrus clouds yields their ice water content.

  18. Direct Measurement of Large, Diffuse, Optical Structures

    NASA Technical Reports Server (NTRS)

    Saif, Babak N.; Keski-Kuha, Ritva; Feinberg, Lee; Wyant, J. C.; Atkinson, C.

    2004-01-01

    Digital Speckle Pattern Interferometry (DSPI) is a well-established method for the measurement of diffuse objects in experimental mechanics. DSPIs are phase shifting interferometers. Three or four bucket temporal phase shifting algorithms are commonly used to provide phase shifting. These algorithms are sensitive to vibrations and can not be used to measure large optical structures far away from the interferometer. In this research a simultaneous phase shifted interferometer, PhaseCam product of 4D Technology Corporation in Tucson Arizona, is modified to be a Simultaneous phase shifted Digital Speckle Pattern Interferometer (SDSPI). Repeatability, dynamic range, and accuracy of the SDSPI are characterized by measuring a 5 cm x 5 cm carbon fiber coupon.

  19. Continuous strife for better coverage and more details in ocean surface winds measurements - from Midori and ADEOS-2 to GCOM

    NASA Technical Reports Server (NTRS)

    Xie, X.; Liu, W.; Hu, H.; Tang, W.

    2001-01-01

    The series of joint U.S.-Japan spaceborne scatterometers missions to provide continuous measurements of ocean wind vectors is reviewed. Examples of the scientific impact of the continuous effort in improving spatial resolution and coverage are provided. The plan for the future is reviewed.

  20. In-situ spatio-temporal measurements of the detailed substructure of the substorm current wedge and its evolution (Invited)

    NASA Astrophysics Data System (ADS)

    Forsyth, C.; Fazakerley, A. N.; Rae, I. J.; Watt, C. E.; Murphy, K. R.; Wild, J. A.; Karlsson, T.; Mutel, R. L.; Owen, C. J.; Ergun, R.; Masson, A.; Donovan, E.; Frey, H. U.; Matzka, J.; Stolle, C.; Zhang, Y.

    2013-12-01

    The substorm current wedge (SCW) is a fundamental component of geomagnetic substorms. Models tend to describe the SCW as a simple line current flowing into the ionosphere towards dawn and out of the ionosphere towards dusk, linked by a westward electrojet. We use multi-spacecraft observations from perigee passes of the Cluster 1 and 4 spacecraft during a substorm on 15 Jan 2010, in conjunction with ground-based observations, to examine the spatial structuring and temporal variability of the SCW. At this time, the spacecraft travelled east-west azimuthally above the auroral region. We show that the SCW has significant azimuthal sub-structure on scales of 100s km at altitudes of 4,000-7,000 km. We identify 26 individual current sheets in the Cluster 4 data and 34 individual current sheets in the Cluster 1 data, with Cluster 1 passing through the SCW 120-240 s after Cluster 4 at 1,300-2,000 km higher altitude. Both spacecraft observed large-scale regions of net upward and downward field-aligned current, consistent with the large-scale characteristics of the SCW, although sheets of oppositely directed currents were observed within both regions. We show that the majority of these current sheets were closely aligned to a north-south direction, in contrast to the expected east-west orientation of the pre-onset aurora. Comparing our results with observations of the field-aligned current associated with bursty bulk flows (BBFs) we conclude that the structuring of the SCW cannot solely be due to BBF driven "wedgelets". Our results therefore represent constraints on future modeling and theoretical frameworks on the generation of the SCW.

  1. Detailed Project Report and Environmental Assessment on Upper Gordons Creek, Urban Flood Damage Reduction Measures at Hattiesburg, Mississippi.

    DTIC Science & Technology

    1986-09-01

    1 Jan 87 1 May 87 Real Estate Acquisition and Evacuation of Structures between Kamper Park and U.S. Highway 11 1 Jan 87 1 May 87 Channel Enlargement...Broad St. to Hardy St. 1 Jan 87 31 Dec 87 Non-Federal Real Estate Acquisition 1 Jan 87 1 May 87 Non-Federal Relocations 1 Jan 87 1 May 87 Plans and...40th Av. 1 Oct 88 31 Dec 89 Non-Federal Real Estate Acquisition 1 Oct 88 1 May 89 Non-Federal Relocations 1 Oct 88 1 May 89 Plans and Specifications 1

  2. Detailed heat transfer coefficient measurements and thermal analysis at engine conditions of a pedestal with fillet radii

    NASA Astrophysics Data System (ADS)

    Wang, Z.; Ireland, P. T.; Jones, T. V.

    1995-04-01

    The heat transfer coefficient over the surface of a pedestal with fillet radii has been measured using thermochromic liquid crystals and the transient heat transfer method. The tests were performed at engine representative Reynolds numbers for a geometry typical of those used in turbine blade cooling systems. The heat conduction process that occurs in the engine was subsequently modeled numerically with a finite element discretization of the solid pedestal. The measured heat transfer coefficients were used to derive the exact boundary conditions applicable to the engine. The temperature field within the pedestal, calculated using the correct heat transfer coefficient distribution, is compared to that calculated using an area-averaged heat transfer coefficient. Metal temperature differences of 90 K are predicted across the blade wall.

  3. Detailed measurements and shaping of gate profiles for microchannel-plate-based X-ray framing cameras

    SciTech Connect

    Landen, O.L.; Hammel, B.A.; Bell, P.M.; Abare, A. |; Bradley, D.K. |

    1994-10-03

    Gated, microchannel-plate-based (MCP) framing cameras are increasingly used worldwide for x-ray imaging of subnanosecond laser-plasma phenomena. Large dynamic range (> 1,000) measurements of gain profiles for gated microchannel plates (MCP) are presented. Temporal profiles are reconstructed for any point on the microstrip transmission line from data acquired over many shots with variable delay. No evidence for significant pulse distortion by voltage reflections at the ends of the microstrip is observed. The measured profiles compare well to predictions by a time-dependent discrete dynode model down to the 1% level. The calculations do overestimate the contrast further into the temporal wings. The role of electron transit time dispersion in limiting the minimum achievable gate duration is then investigated by using variable duration flattop gating pulses. A minimum gate duration of 50 ps is achieved with flattop gating, consistent with a fractional transit time spread of {approx} 15%.

  4. Detailed measurements of the H beta line shape in a transient plasma using a fiber optics slit system

    NASA Technical Reports Server (NTRS)

    Stickford, G. H., Jr.

    1972-01-01

    Through the use of fiber optics, a series of very narrow slits have been constructed and placed at the exit plane of a spectrograph. Plasma radiation which is dispersed by the spectrograph is incident on the slits and is transmitted to separate phototubes via the quartz fibers. With this technique, time resolved measurements of the spectral shape of the hydrogen H beta line have been made and used to determine the electron density of a transient plasma. Data obtained in a shock tube indicated that the thermodynamic conditions behind the reflected shock in a mixture of 20 percent H 80 percent He correspond to theoretically predicted conditions.

  5. Detailed measurements of local heat transfer coefficient and adiabatic wall temperature beneath an array of impinging jets

    SciTech Connect

    Van Treuren, K.W.; Wang, Z.; Ireland, P.T.; Jones, T.V. . Dept. of Engineering Science)

    1994-07-01

    A transient method of measuring the local heat transfer under an array of impinging jets has been developed. The use of a temperature-sensitive coating consisting of three encapsulated thermochromic liquid crystal materials has allowed the calculation of both the local adiabatic wall temperature and the local heat transfer coefficient over the complete surface of the target plate. The influence of the temperature of the plate through which the impingment gas flows on the target plate heat transfer has been quantified. Results are presented for a single in-line array configuration over a range of jet Reynolds numbers.

  6. Towards detailed knowledge of atomic nuclei—the past, present and future of nuclear structure investigations at GSI

    NASA Astrophysics Data System (ADS)

    Gerl, J.; Gorska, M.; Wollersheim, H. J.

    2016-10-01

    Selected experimental nuclear structure physics results are presented which have been obtained at GSI since the mid 70ties employing the UNILAC and the SIS/FRS accelerator facility. It is shown how stable heavy-ion beams as well as radioactive isotope beams of this facility together with state-of-the-art instrumentation produced many discoveries and led to a multitude of important results covering many aspects of nuclear structure. Finally, we discuss the future directions of nuclear structure research at GSI with the FAIR/NUSTAR project.

  7. Detailed beam and plasma measurements on the vessel for extraction and source plasma analyses (VESPA) Penning H⁻ ion source.

    PubMed

    Lawrie, S R; Faircloth, D C; Letchford, A P; Whitehead, M O; Wood, T

    2016-02-01

    A vessel for extraction and source plasma analyses (VESPA) is operational at the Rutherford Appleton Laboratory (RAL). This project supports and guides the overall ion source R&D effort for the ISIS spallation neutron and muon facility at RAL. The VESPA produces 100 mA of pulsed H(-) beam, but perveance scans indicate that the source is production-limited at extraction voltages above 12 kV unless the arc current is increased. A high resolution optical monochromator is used to measure plasma properties using argon as a diagnostic gas. The atomic hydrogen temperature increases linearly with arc current, up to 2.8 eV for 50 A; whereas the electron temperature has a slight linear decrease toward 2.2 eV. The gas density is 10(21) m(-3), whilst the electron density is two orders of magnitude lower. Densities follow square root relationships with arc current, with gas density decreasing whilst electron (and hence ion) density increases. Stopping and range of ions in matter calculations prove that operating a high current arc with an argon admixture is extremely difficult because cathode-coated cesium is heavily sputtered by argon.

  8. Detailed beam and plasma measurements on the vessel for extraction and source plasma analyses (VESPA) Penning H- ion source

    NASA Astrophysics Data System (ADS)

    Lawrie, S. R.; Faircloth, D. C.; Letchford, A. P.; Whitehead, M. O.; Wood, T.

    2016-02-01

    A vessel for extraction and source plasma analyses (VESPA) is operational at the Rutherford Appleton Laboratory (RAL). This project supports and guides the overall ion source R&D effort for the ISIS spallation neutron and muon facility at RAL. The VESPA produces 100 mA of pulsed H- beam, but perveance scans indicate that the source is production-limited at extraction voltages above 12 kV unless the arc current is increased. A high resolution optical monochromator is used to measure plasma properties using argon as a diagnostic gas. The atomic hydrogen temperature increases linearly with arc current, up to 2.8 eV for 50 A; whereas the electron temperature has a slight linear decrease toward 2.2 eV. The gas density is 1021 m-3, whilst the electron density is two orders of magnitude lower. Densities follow square root relationships with arc current, with gas density decreasing whilst electron (and hence ion) density increases. Stopping and range of ions in matter calculations prove that operating a high current arc with an argon admixture is extremely difficult because cathode-coated cesium is heavily sputtered by argon.

  9. Implications of Model Structure and Detail for Utility Planning: Scenario Case Studies Using the Resource Planning Model

    SciTech Connect

    Mai, Trieu; Barrows, Clayton; Lopez, Anthony; Hale, Elaine; Dyson, Mark; Eurek, Kelly

    2015-04-01

    In this report, we analyze the impacts of model configuration and detail in capacity expansion models, computational tools used by utility planners looking to find the least cost option for planning the system and by researchers or policy makers attempting to understand the effects of various policy implementations. The present analysis focuses on the importance of model configurations — particularly those related to capacity credit, dispatch modeling, and transmission modeling — to the construction of scenario futures. Our analysis is primarily directed toward advanced tools used for utility planning and is focused on those impacts that are most relevant to decisions with respect to future renewable capacity deployment. To serve this purpose, we develop and employ the NREL Resource Planning Model to conduct a case study analysis that explores 12 separate capacity expansion scenarios of the Western Interconnection through 2030.

  10. Predicted 3D structures of olfactory receptors with details of odorant binding to OR1G1

    NASA Astrophysics Data System (ADS)

    Kim, Soo-Kyung; Goddard, William A.

    2014-12-01

    Olfactory receptors (ORs) are responsible for mediating the sense of smell; they allow humans to recognize an enormous number of odors but the connection between binding and perception is not known. We predict the ensemble of low energy structures for the human OR1G1 (hOR1G1) and also for six other diverse ORs, using the G protein-coupled receptor Ensemble of Structures in Membrane BiLayer Environment complete sampling method that samples 13 trillion different rotations and tilts using four different templates to predict the 24 structures likely to be important in binding and activation. Our predicted most stable structures of hOR1G1 have a salt-bridge between the conserved D3.49 and K6.30 in the D(E)RY region, that we expect to be associated with an inactive form. The hOR1G1 structure also has specific interaction in transmembrane domains (TMD) 3-6 (E3.39 and H6.40), which is likely an important conformational feature for all hORs because of the 94 to 98 % conservation among all hOR sequences. Of the five ligands studied (nonanal, 9-decen-1-ol, 1-nonanol, camphor, and n-butanal), we find that the 4 expected to bind lead to similar binding energies with nonanol the strongest.

  11. Reflectron MALDI TOF and MALDI TOF/TOF mass spectrometry reveal novel structural details of native lipooligosaccharides.

    PubMed

    Sturiale, Luisa; Palmigiano, Angelo; Silipo, Alba; Knirel, Yuriy A; Anisimov, Andrei P; Lanzetta, Rosa; Parrilli, Michelangelo; Molinaro, Antonio; Garozzo, Domenico

    2011-11-01

    Lipooligosaccharides (LOS) are powerful Gram-negative glycolipids that evade the immune system and invade host animal and vegetal cells. The structural elucidation of LOS is pivotal to understanding the mechanisms of infection at the molecular level. The amphiphilic nature of LOS has been the main obstacle for structural analysis by matrix-assisted laser desorption/ionization (MALDI) mass spectrometry (MS). Our approach has resolved this important issue and has permitted us to obtain reflectron MALDI mass spectra of LOS to reveal the fine chemical structure with minimal structural variations. The high-quality MALDI mass spectra show LOS species characteristic of molecular ions and defined fragments due to decay in the ion source. The in-source decay yields B-type ions, which correspond to core oligosaccharide(s), and Y-type ions, which are related to lipid A unit(s). MALDI tandem time-of-flight (TOF/TOF) MS of lipid A allowed for the elucidation of its structure directly from purified intact LOS without the need for any chemical manipulations. These findings constitute a significant advancement in the analysis of such an important biomolecule by MALDI MS. Copyright © 2011 John Wiley & Sons, Ltd.

  12. The use of ultraviolet Thomson scattering as a versatile diagnostic for detailed measurements of a collisional laser produced plasma

    SciTech Connect

    Tracy, Mark David

    1993-01-08

    Collective Thomson scattering from ion-acoustic waves at 266nm is used to obtain spatially resolved, two-dimensional electron density, sound speed, and radial drift profiles of a collisional laser plasma. An ultraviolet diagnostic wavelength minimizes the complicating effects of inverse bremsstrahlung and refractive turning in the coronal region of interest, where the electron densities approach nc/10. Laser plasmas of this type are important because they model some of the aspects of the plasmas found in high-gain laser-fusion pellets irradiated by long pulse widths where the laser light is absorbed mostly in the corona. The experimental results and LASNEX simulations agree within a percent standard deviation of 40% for the electron density and 50% for the sound speed and radial drift velocity. Thus it is shown that the hydrodynamics equations with classical coefficients and the numerical approximations in LASNEX are valid models of laser-heated, highly collisional plasmas. The versatility of Thomson scattering is expanded upon by extending existing theory with a Fokker-Planck based model to include plasmas that are characterized by (0 ≤ kiaλii ≤ ∞) and ZTe/Ti, where kia is the ion- acoustic wave number, λii is the ion-ion mean free path, Z is the ionization state of the plasma, and Te. Ti are the electron and ion temperatures in electron volts respectively. The model is valid for plasmas in which the electrons are approximately collisionless, (kiaλei, kiaλee ≥ 1), and quasineutrality holds, (α ≥1), where α = 1/kλDE and λDe is the electron Debye length. This newly developed model predicts the lineshape of the ion-acoustic Thomson spectra and when fit to experimental data provides a direct measurement of the relative thermal flow velocity between the electrons and ions.

  13. Measurement of surface scratches on aircraft structures

    NASA Astrophysics Data System (ADS)

    Sarr, Dennis P.

    1996-01-01

    In assuring the quality of aircraft, the skin quality must be free of surface imperfections. Surface imperfections such as scratches are unacceptable for cosmetic and structural reasons. Scratches beyond a certain depth are not repairable, resulting in costly replacement of an aircraft's part. Measurements of aircraft exterior surfaces require a ladder or cherry picker for positioning the inspector. Commercially-available computer vision systems are not portable, easy to use, or ergonomic. The machine vision system must be designed with these criteria in mind. The scratch measurement system (SMS) uses computer vision, digital signal processing, and automated inspection methods. The system is portable and battery powered. It is certified for measuring the depth and width of the anomaly. The SMS provides a comprehensive, analytical, and accurate reading. A hardcopy output provides a permanent record of the analysis. The graphical data shows the surface profile and provides substantial information of the surface anomaly. The factory and flight line use the SMS at different stages of aircraft production. Six systems have been built for use within Boeing. A patent was issued for the SMS in February 1994.

  14. 10. DETAIL, CAB SIDE. DETAIL, END OF BOOM. DETAIL, LOWER ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    10. DETAIL, CAB SIDE. DETAIL, END OF BOOM. DETAIL, LOWER PART OF TOWER, SHOWING METAL WHEELS AND CABLE SPOOLS. DETAIL, LOOKING UP AT THE UNDERSIDE OF THE REVOLVING PLATFORM ATOP THE TOWER. - United Engineering Company Shipyard, Crane, 2900 Main Street, Alameda, Alameda County, CA

  15. Structural Characterization by Cross-linking Reveals the Detailed Architecture of a Coatomer-related Heptameric Module from the Nuclear Pore Complex*

    PubMed Central

    Shi, Yi; Fernandez-Martinez, Javier; Tjioe, Elina; Pellarin, Riccardo; Kim, Seung Joong; Williams, Rosemary; Schneidman-Duhovny, Dina; Sali, Andrej; Rout, Michael P.; Chait, Brian T.

    2014-01-01

    Most cellular processes are orchestrated by macromolecular complexes. However, structural elucidation of these endogenous complexes can be challenging because they frequently contain large numbers of proteins, are compositionally and morphologically heterogeneous, can be dynamic, and are often of low abundance in the cell. Here, we present a strategy for the structural characterization of such complexes that has at its center chemical cross-linking with mass spectrometric readout. In this strategy, we isolate the endogenous complexes using a highly optimized sample preparation protocol and generate a comprehensive, high-quality cross-linking dataset using two complementary cross-linking reagents. We then determine the structure of the complex using a refined integrative method that combines the cross-linking data with information generated from other sources, including electron microscopy, X-ray crystallography, and comparative protein structure modeling. We applied this integrative strategy to determine the structure of the native Nup84 complex, a stable hetero-heptameric assembly (∼600 kDa), 16 copies of which form the outer rings of the 50-MDa nuclear pore complex (NPC) in budding yeast. The unprecedented detail of the Nup84 complex structure reveals previously unseen features in its pentameric structural hub and provides information on the conformational flexibility of the assembly. These additional details further support and augment the protocoatomer hypothesis, which proposes an evolutionary relationship between vesicle coating complexes and the NPC, and indicates a conserved mechanism by which the NPC is anchored in the nuclear envelope. PMID:25161197

  16. Structural outline of the detailed mechanism for elongation factor Ts-mediated guanine nucleotide exchange on elongation factor Tu.

    PubMed

    Thirup, Søren S; Van, Lan Bich; Nielsen, Tine K; Knudsen, Charlotte R

    2015-07-01

    Translation elongation factor EF-Tu belongs to the superfamily of guanine-nucleotide binding proteins, which play key cellular roles as regulatory switches. All G-proteins require activation via exchange of GDP for GTP to carry out their respective tasks. Often, guanine-nucleotide exchange factors are essential to this process. During translation, EF-Tu:GTP transports aminoacylated tRNA to the ribosome. GTP is hydrolyzed during this process, and subsequent reactivation of EF-Tu is catalyzed by EF-Ts. The reaction path of guanine-nucleotide exchange is structurally poorly defined for EF-Tu and EF-Ts. We have determined the crystal structures of the following reaction intermediates: two structures of EF-Tu:GDP:EF-Ts (2.2 and 1.8Å resolution), EF-Tu:PO4:EF-Ts (1.9Å resolution), EF-Tu:GDPNP:EF-Ts (2.2Å resolution) and EF-Tu:GDPNP:pulvomycin:Mg(2+):EF-Ts (3.5Å resolution). These structures provide snapshots throughout the entire exchange reaction and suggest a mechanism for the release of EF-Tu in its GTP conformation. An inferred sequence of events during the exchange reaction is presented.

  17. Statistical Measures of Large-Scale Structure

    NASA Astrophysics Data System (ADS)

    Vogeley, Michael; Geller, Margaret; Huchra, John; Park, Changbom; Gott, J. Richard

    1993-12-01

    \\inv Mpc} To quantify clustering in the large-scale distribution of galaxies and to test theories for the formation of structure in the universe, we apply statistical measures to the CfA Redshift Survey. This survey is complete to m_{B(0)}=15.5 over two contiguous regions which cover one-quarter of the sky and include ~ 11,000 galaxies. The salient features of these data are voids with diameter 30-50\\hmpc and coherent dense structures with a scale ~ 100\\hmpc. Comparison with N-body simulations rules out the ``standard" CDM model (Omega =1, b=1.5, sigma_8 =1) at the 99% confidence level because this model has insufficient power on scales lambda >30\\hmpc. An unbiased open universe CDM model (Omega h =0.2) and a biased CDM model with non-zero cosmological constant (Omega h =0.24, lambda_0 =0.6) match the observed power spectrum. The amplitude of the power spectrum depends on the luminosity of galaxies in the sample; bright (L>L(*) ) galaxies are more strongly clustered than faint galaxies. The paucity of bright galaxies in low-density regions may explain this dependence. To measure the topology of large-scale structure, we compute the genus of isodensity surfaces of the smoothed density field. On scales in the ``non-linear" regime, <= 10\\hmpc, the high- and low-density regions are multiply-connected over a broad range of density threshold, as in a filamentary net. On smoothing scales >10\\hmpc, the topology is consistent with statistics of a Gaussian random field. Simulations of CDM models fail to produce the observed coherence of structure on non-linear scales (>95% confidence level). The underdensity probability (the frequency of regions with density contrast delta rho //lineρ=-0.8) depends strongly on the luminosity of galaxies; underdense regions are significantly more common (>2sigma ) in bright (L>L(*) ) galaxy samples than in samples which include fainter galaxies.

  18. Detailed structural study of β-artemether: Density functional theory (DFT) calculations of Infrared, Raman spectroscopy, and vibrational circular dichroism

    NASA Astrophysics Data System (ADS)

    Wang, Zhiqiang; Chen, Jianchao; Li, Linwei; Zhou, Zhixu; Geng, Yiding; Sun, Tiemin

    2015-10-01

    In this study, the experimental and theoretical studies on the structure of β-artemether are presented. The optimized molecular structure, Mulliken atomic charges, vibrational spectra (IR, Raman and vibrational circular dichroism), and molecular electrostatic potential have been calculated by density functional theory (DFT) using B3LYP method with the 6-311++G (2d, p) basis set. Reliable vibrational assignments for Artemether have been made on the basis of potential energy distribution (PED). The vibrational circular dichroism (VCD) has been explored by ab initio calculations, and then was used to compare with the experimental VCD. The consistence between them confirmed the absolute configuration of Artemether. In addition, HOMO-LUMO of the title compound as well as thermo-dynamical parameters has illustrated the stability of β-artemether.

  19. SMS crew station (C and D panels and forward structures). CEI part 1: Detail specification, type 1 data

    NASA Technical Reports Server (NTRS)

    1976-01-01

    Established are the requirements for performance, design, test and qualification of one type of equipment identified as SMS C&D panels and forward structures. This CEI is used to provide all hardware and wiring necessary for the C&D panels to be properly interfaced with the computer complex/signal conversion equipment (SCE), crew station, and software requirements as defined in other CEI specifications.

  20. Measurements of cellular structure in spray detonation

    SciTech Connect

    Papavassiliou, J.; Makris, A.; Knystautas, R.; Lee, J.H.; Westbrook, C.K.; Pitz, W.J.

    1991-10-01

    The cellular structure of heterogeneous detonations in a low vapor pressure fuel (decane) droplet mixture with oxygen and oxygen-nitrogen was studied in the present investigation. The aerosol was generated by an ultrasonic nebulizer and the fuel concentration of the mixture was regulated by monitoring the volume flow rate of oxygen and nitrogen through the nebulizer. The vertical detonation tube is 64 mm in diameter and 3 m long and ignition was by a powerful spark (120 joules stored energy) or a high explosive detonator. Velocity was measured with ionization probes, pressure by a PCB piezoelectric transducer and cell size by a smoked metallic foil inserted into the top end or centre of the detonation tube. The initial pressure of all the experiments was 1 atmosphere. In order to compare the time scales associated with the physical processes of droplet breakup, heat transfer, evaporation, and mixing, experiments were also carried out in the tube heated to 100{degree}C and 185{degree}C, using electrical heating tape, to ensure a homogeneous gas phase mixture of decane-oxygen-nitrogen. Comparison of the cell size for the same mixture in the cold and the heated tube permits one to separate the time scales associated with the physical processes and the chemical kinetic rate processes. The results from the heated tube for the homogeneous vapor phase decane detonations are similar to those for the common gaseous fuels in the alkane group (i.e. ethane, propane, butane). Corresponding results for the heterogeneous case (cold tube) of aerosol decane detonation indicate that the cell size is larger by a factor of about 2, for the present case of 5 {mu}m particle size. The measurements of cellular structure obtained experimentally have been compared to the computed results determined using the ZND chemical kinetic detonation model.

  1. Structural Imaging Measures of Brain Aging

    PubMed Central

    Lockhart, Samuel N.

    2014-01-01

    During the course of normal aging, biological changes occur in the brain that are associated with changes in cognitive ability. This review presents data from neuroimaging studies of primarily “normal” or healthy brain aging. As such, we focus on research in unimpaired or nondemented older adults, but also include findings from lifespan studies that include younger and middle aged individuals as well as from populations with prodromal or clinically symptomatic disease such as cerebrovascular or Alzheimer’s disease. This review predominantly addresses structural MRI biomarkers, such as volumetric or thickness measures from anatomical images, and measures of white matter injury and integrity respectively from FLAIR or DTI, and includes complementary data from PET and cognitive or clinical testing as appropriate. The findings reveal highly consistent age-related differences in brain structure, particularly frontal lobe and medial temporal regions that are also accompanied by age-related differences in frontal and medial temporal lobe mediated cognitive abilities. Newer findings also suggest that degeneration of specific white matter tracts such as those passing through the genu and splenium of the corpus callosum may also be related to age-related differences in cognitive performance. Interpretation of these findings, however, must be tempered by the fact that comorbid diseases such as cerebrovascular and Alzheimer’s disease also increase in prevalence with advancing age. As such, this review discusses challenges related to interpretation of current theories of cognitive aging in light of the common occurrence of these later-life diseases. Understanding the differences between “Normal” and “Healthy” brain aging and identifying potential modifiable risk factors for brain aging is critical to inform potential treatments to stall or reverse the effects of brain aging and possibly extend cognitive health for our aging society. PMID:25146995

  2. The electronic structure and second-order nonlinear optical properties of donor-acceptor acetylenes - A detailed investigation of structure-property relationships

    NASA Technical Reports Server (NTRS)

    Stiegman, A. E.; Graham, Eva; Khundkar, Lutfur R.; Perry, Joseph W.; Cheng, L.-T.; Perry, Kelly J.

    1991-01-01

    A series of donor-acceptor acetylene compounds was synthesized in which systematic changes in both the conjugation length and the donor-acceptor strength were made. The effect of these structural changes on the spectroscopic and electronic properties of the molecules and, ultimately, on the measured second-order molecular hyperpolarizabilities (beta) was investigated. It was found that increases in the donor-acceptor strength resulted in increases in the magnitude of beta. For this class of molecules, the increase is dominated by the energy of the intramolecular charge-transfer transition, while factors such as the ground to excited-state dipole moment change and the transition-moment integral are much less important. Increasing the conjugation length from one to two acetylene linkers did not result in an increase in the value of beta; however, beta increased sharply in going from two acetylenes to three. This increase is attributed to the superposition of several nearly isoenergetic excited states.

  3. Greenland annual accumulation along the EGIG line, 1959-2004, from ASIRAS airborne radar and detailed neutron-probe density measurements

    NASA Astrophysics Data System (ADS)

    Overly, T. B.; Hawley, R. L.; Helm, V.; Morris, E. M.; Chaudhary, R. N.

    2015-12-01

    We report annual snow accumulation rates from 1959 to 2004 along a 250 km segment of the Expéditions Glaciologiques Internationales au Groenland (EGIG) line across central Greenland using Airborne SAR/Interferometric Radar Altimeter System (ASIRAS) radar layers and detailed neutron-probe (NP) density profiles. ASIRAS-NP accumulation rates are not statistically different (C.I. 95 %) from in situ EGIG accumulation measurements from 1985 to 2004. Below 3000 m elevation, ASIRAS-NP increases by 20 % for the period 1995 to 2004 compared to 1985 to 1994. Above 3000 m elevation, accumulation increases by 13 % for 1995-2004 compared to 1985-1994. Model snow accumulation results from the calibrated Fifth Generation Mesoscale Model modified for polar climates (Polar MM5) underestimate mean annual accumulation by 16 % compared to ASIRAS-NP from 1985 to 2004. We test radar-derived accumulation rates sensitivity to density using modelled density profiles in place of detailed NP data. ASIRAS radar layers combined with Herron and Langway (1980) model density profiles (ASIRAS-HL) produce accumulation rates within 3.5 % of ASIRAS-NP estimates. We suggest using Herron and Langway (1980) density profiles to calibrate radar layers detected in dry snow regions of ice sheets lacking detailed in situ density measurements, such as those observed by the IceBridge campaign.

  4. Thermodynamics and Interior Structure Measurements of Ocean Worlds

    NASA Astrophysics Data System (ADS)

    Vance, S.; Brown, J. M.; Bollengier, O.; Bills, B. G.; Castillo, J. C.; Choukroun, M.; Jackson, J. M.; Kedar, S.; Tsai, V. C.

    2015-12-01

    Extending thermodynamics of aqueous solutions to elevated salinity and pressure is key to understanding icy moon oceans. Such a project is intrinsically linked to future seismic investigations, which would offer the most comprehensive views into the deep interiors of planetary bodies. The InSight Mars mission and Europa Lander mission concept both identify seismology as a critical measurement to constrain interior structure and thermal state of astrobiological targets. By pinpointing the radial depths of compositional interfaces, seismology in a broad frequency range can address uncertainty in interior structures inferred from gravity and magnetometry studies, such as those planned for the NASA's Europa and ESA's JUICE missions. Seismology also offers information about fluid motions within or beneath ice, which complement magnetic studies; and can record the dynamics of ice layers, which would reveal mechanisms and spatiotemporal occurrence of crack formation and propagation. Investigating these in the future calls for detailed modeling of seismic sources and signatures. Thermodynamic measurements of sound velocities and elastic moduli can provide needed seismic model inputs, as well as associated densities, thermal expansion, heat capacities, and chemical potentials for modeling interior structure. Sound speed profiles built from our internal structure models for Ganymede (Vance et al. 2014), using thermodynamically consistent data (Shaw 1986, Vance and Brown 2013) point to needed research, both in developing thermodynamic data from new laboratory measurements and applying them to problems in planetary geophysics. Comparing these profiles with simulated electrical conductivities of MgSO4 along the geotherms illustrates how dual seismology-magnetometry investigations can infer ocean density structure and salinity. Electrical conductivities are based on measurements by Larionov (1984) and Huang and Papangelakis (2006), and extrapolation to 273 K by Hand and Chyba

  5. Detailed Relationship Between Local Structure Polarons and Magnetization for La1-xCaxMnO3 (0.21 lt x lt 0.45)

    SciTech Connect

    F Bridges; L Downward; J Neumeier; T Tyson

    2011-12-31

    We present detailed local structure measurements (using the extended x-ray absorption fine structure technique) for the colossal magnetoresistive material La{sub 1-x}Ca{sub x}MnO{sub 3} (0.21 < x < 0.45) as a function of temperature and magnetic field. The local distortions of the Mn-O bonds are parameterized using {sigma}, the width of the Mn-O pair-distribution function (PDF). After subtracting thermal phonon contributions, we show that the contributions to {sigma}{sup 2} from polaron and Jahn-Teller (JT) distortions, {sigma}{sub JT/polaron}{sup 2}, are a universal function of the magnetization, independent of how the magnetization is achieved via changes in temperature or magnetic field. However this universal behavior is only observed for B fields {ge} 2 T, likely as a result of domain canting in low B fields. The resulting curve is well described by two straight lines with significantly different slopes. These regimes represent two distinctly differ distortions of the oxygen octahedra about the Mn. For low magnetizations up to {approx}65% of the theoretical maximum magnetization, M{sub T}, the slope is low and the distortion removed as the sample becomes magnetized is small - we argue this arises from polarons which have a low distortion around two (or possibly three) Mn sites. At high magnetizations large distortions per Mn site are removed as these sites become magnetized. The data are also analyzed in terms of a two Mn-O peak distribution using experimental standards for Mn-O. The results agree well with recent neutron PDF results but not with some earlier results. We discuss the limitations of assuming a two peak distribution in view of the two distortions needed to describe the Mn-O distortions as a function of T and B for B {ge} 2 T. It is likely that there is a distribution of longer bonds. Finally we show that with increasing B field, the Mn-Mn peak also has a small B-field-induced change - a measure at the unit cell level of magnetostriction but find

  6. Structure of nonevaporating sprays - Measurements and predictions

    NASA Technical Reports Server (NTRS)

    Solomon, A. S. P.; Shuen, J.-S.; Zhang, Q.-F.; Faeth, G. M.

    1984-01-01

    Structure measurements were completed within the dilute portion of axisymmetric nonevaporating sprays (SMD of 30 and 87 microns) injected into a still air environment, including: mean and fluctuating gas velocities and Reynolds stress using laser-Doppler anemometry; mean liquid fluxes using isokinetic sampling; drop sizes using slide impaction; and drop sizes and velocities using multiflash photography. The new measurements were used to evaluate three representative models of sprays: (1) a locally homogeneous flow (LHF) model, where slip between the phases was neglected; (2) a deterministic separated flow (DSF) model, where slip was considered but effects of drop interaction with turbulent fluctuations were ignored; and (3) a stochastic separated flow (SSF) model, where effects of both interphase slip and turbulent fluctuations were considered using random sampling for turbulence properties in conjunction with random-walk computations for drop motion. The LHF and DSF models were unsatisfactory for present test conditions-both underestimating flow widths and the rate of spread of drops. In contrast, the SSF model provided reasonably accurate predictions, including effects of enhanced spreading rates of sprays due to drop dispersion by turbulence, with all empirical parameters fixed from earlier work.

  7. Micro- and nano-structural details of a spider's filter for substrate vibrations: relevance for low-frequency signal transmission

    PubMed Central

    Erko, Maxim; Younes-Metzler, Osnat; Rack, Alexander; Zaslansky, Paul; Young, Seth L.; Milliron, Garrett; Chyasnavichyus, Marius; Barth, Friedrich G.; Fratzl, Peter; Tsukruk, Vladimir; Zlotnikov, Igor; Politi, Yael

    2015-01-01

    The metatarsal lyriform organ of the Central American wandering spider Cupiennius salei is its most sensitive vibration detector. It is able to sense a wide range of vibration stimuli over four orders of magnitude in frequency between at least as low as 0.1 Hz and several kilohertz. Transmission of the vibrations to the slit organ is controlled by a cuticular pad in front of it. While the mechanism of high-frequency stimulus transfer (above ca 40 Hz) is well understood and related to the viscoelastic properties of the pad's epicuticle, it is not yet clear how low-frequency stimuli (less than 40 Hz) are transmitted. Here, we study how the pad material affects the pad's mechanical properties and thus its role in the transfer of the stimulus, using a variety of experimental techniques, such as X-ray micro-computed tomography for three-dimensional imaging, X-ray scattering for structural analysis, and atomic force microscopy and scanning electron microscopy for surface imaging. The mechanical properties were investigated using scanning acoustic microscopy and nanoindentation. We show that large tarsal deflections cause large deformation in the distal highly hydrated part of the pad. Beyond this region, a sclerotized region serves as a supporting frame which resists the deformation and is displaced to push against the slits, with displacement values considerably scaled down to only a few micrometres. Unravelling the structural arrangement in such specialized structures may provide conceptual ideas for the design of new materials capable of controlling a technical sensor's specificity and selectivity, which is so typical of biological sensors. PMID:25631567

  8. On the structure of amorphous calcium carbonate--a detailed study by solid-state NMR spectroscopy.

    PubMed

    Nebel, Holger; Neumann, Markus; Mayer, Christian; Epple, Matthias

    2008-09-01

    The calcium carbonate phases calcite, aragonite, vaterite, monohydrocalcite (calcium carbonate monohydrate), and ikaite (calcium carbonate hexahydrate) were studied by solid-state NMR spectroscopy ( (1)H and (13)C). Further model compounds were sodium hydrogencarbonate, potassium hydrogencarbonate, and calcium hydroxide. With the help of these data, the structure of synthetically prepared additive-free amorphous calcium carbonate (ACC) was analyzed. ACC contains molecular water (as H 2O), a small amount of mobile hydroxide, and no hydrogencarbonate. This supports the concept of ACC as a transient precursor in the formation of calcium carbonate biominerals.

  9. Detailed cross sections of the Eocene Green River Formation along the north and east margins of the Piceance Basin, western Colorado, using measured sections and drill hole information

    USGS Publications Warehouse

    Johnson, Ronald C.

    2014-01-01

    This report presents two detailed cross sections of the Eocene Green River Formation in the Piceance Basin, northwestern Colorado, constructed from eight detailed measured sections, fourteen core holes, and two rotary holes. The Eocene Green River Formation in the Piceance Basin contains the world’s largest known oil shale deposit with more than 1.5 billion barrels of oil in place. It was deposited in Lake Uinta, a long-lived saline lake that once covered much of the Piceance Basin and the Uinta Basin to the west. The cross sections extend across the northern and eastern margins of the Piceance Basin and are intended to aid in correlating between surface sections and the subsurface in the basin.

  10. Inferring electromagnetic ion cyclotron wave intensity from low altitude POES proton flux measurements: A detailed case study with conjugate Van Allen Probes observations

    NASA Astrophysics Data System (ADS)

    Zhang, Yang; Shi, Run; Ni, Binbin; Gu, Xudong; Zhang, Xianguo; Zuo, Pingbing; Fu, Song; Xiang, Zheng; Wang, Qi; Cao, Xing; Zou, Zhengyang

    2017-03-01

    Electromagnetic ion cyclotron (EMIC) waves play an important role in the magnetospheric particle dynamics and can lead to resonant pitch-angle scattering and ultimate precipitation of ring current protons. Commonly, the statistics of in situ EMIC wave measurements is adopted for quantitative investigation of wave-particle interaction processes, which however becomes questionable for detailed case studies especially during geomagnetic storms and substorms. Here we establish a novel technique to infer EMIC wave amplitudes from low-altitude proton measurements onboard the Polar Operational Environmental Satellites (POES). The detailed procedure is elaborated regarding how to infer the EMIC wave intensity for one specific time point. We then test the technique with a case study comparing the inferred root-mean-square (RMS) EMIC wave amplitude with the conjugate Van Allen Probes EMFISIS wave measurements. Our results suggest that the developed technique can reasonably estimate EMIC wave intensities from low-altitude POES proton flux data, thereby providing a useful tool to construct a data-based, near-real-time, dynamic model of the global distribution of EMIC waves once the proton flux measurements from multiple POES satellites are available for any specific time period.

  11. Structural Details of Ufd1 Binding to p97 and Their Functional Implications in ER-Associated Degradation

    PubMed Central

    Le, Oanh Thi Tu; Lee, Sang Yoon; Yang, Jin Kuk

    2016-01-01

    The hexameric ATPase p97 has been implicated in diverse cellular processes through interactions with many different adaptor proteins at its N-terminal domain. Among these, the Ufd1-Npl4 heterodimer is a major adaptor, and the p97-Ufd1-Npl4 complex plays an essential role in endoplasmic reticulum-associated degradation (ERAD), acting as a segregase that translocates the ubiquitinated client protein from the ER membrane into the cytosol for proteasomal degradation. We determined the crystal structure of the complex of the N-terminal domain of p97 and the SHP box of Ufd1 at a resolution of 1.55 Å. The 11-residue-long SHP box of Ufd1 binds at the far-most side of the Nc lobe of the p97 N domain primarily through hydrophobic interactions, such that F225, F228, N233 and L235 of the SHP box contact hydrophobic residues on the surface of the p97 Nc lobe. Mutating these key interface residues abolished the interactions in two different binding experiments, isothermal titration calorimetry and co-immunoprecipitation. Furthermore, cycloheximide chase assays showed that these same mutations caused accumulation of tyrosinase-C89R, a well-known ERAD substrate, thus implying decreased rate of protein degradation due to their defects in ERAD function. Together, these results provide structural and biochemical insights into the interaction between p97 N domain and Ufd1 SHP box. PMID:27684549

  12. Structure and mutational analysis of the PhoN protein of Salmonella typhimurium provide insight into mechanistic details.

    PubMed

    Makde, Ravindra D; Mahajan, Suresh K; Kumar, Vinay

    2007-02-27

    The Salmonella typhimurium PhoN protein is a nonspecific acid phosphatase and belongs to the phosphatidic acid phosphatase type 2 (PAP2) superfamily. We report here the crystal structures of phosphate-bound PhoN, the PhoN-tungstate complex, and the T159D mutant of PhoN along with functional characterization of three mutants: L39T, T159D, and D201N. Invariant active site residues, Lys-123, Arg-130, Ser-156, Gly-157, His-158, and Arg-191, interact with phosphate and tungstate oxyanions. Ser-156 also accepts a hydrogen bond from Thr-159. The T159D mutation, surprisingly, severely diminishes phosphatase activity, apparently by disturbing the active site scaffold: Arg-191 is swung out of the active site resulting in conformational changes in His-158 and His-197 residues. Our results reveal a hitherto unknown functional role of Arg-191, namely, restricting the active conformation of catalytic His-158 and His-197 residues. Consistent with the conserved nature of Asp-201 in the PAP2 superfamily, the D201N mutation completely abolished phosphatase activity. On the basis of this observation and in silico analysis we suggest that the crucial mechanistic role of Asp-201 is to stabilize the positive charge on the phosphohistidine intermediate generated by the transfer of phosphoryl to the nucleophile, His-197, located within hydrogen bond distance to the invariant Asp-201. This is in contrast to earlier suggestions that Asp-201 stabilizes His-197 and the His197-Asp201 dyad facilitates formation of the phosphoenzyme intermediate through a charge-relay system. Finally, the L39T mutation in the conserved polyproline motif (39LPPPP43) of dimeric PhoN leads to a marginal reduction in activity, in contrast to the nearly 50-fold reduction observed for monomeric Prevotella intermedia acid phosphatase, suggesting that the varying quaternary structure of PhoN orthologues may have functional significance.

  13. Properties of sesame oil by detailed 1H and 13C NMR assignments before and after ozonation and their correlation with iodine value, peroxide value, and viscosity measurements.

    PubMed

    Sega, Alessandro; Zanardi, Iacopo; Chiasserini, Luisa; Gabbrielli, Alessandro; Bocci, Velio; Travagli, Valter

    2010-02-01

    Gaseous ozone chemically reacts with unsaturated triglyceride substrates leading to ozonated derivatives with a wide potential applications, ranging from the petrochemical to the pharmaceutical industry. To date, an ultimate understanding of the ozone reactivity during sesame oil ozonation process as well as detailed (1)H and (13)C NMR assignments are lacking. A practical advantage of NMR is that a single NMR sample measurement can explain many issues, while similar analysis by traditional methods may require several independent and time-consuming measurements. Moreover, significant relationships among NMR spectra and both conventional chemical analysis and viscosity measurements have been found. Eventually, NMR could play an important role for quality attributes of ozonated oil derivatives.

  14. Detailed crustal structure in the area of the southern Apennines-Calabrian Arc border from local earthquake tomography

    NASA Astrophysics Data System (ADS)

    Totaro, C.; Koulakov, I.; Orecchio, B.; Presti, D.

    2014-12-01

    We present a new seismic velocity model for the southern Apennines-Calabrian Arc border region with the aim to better define the crustal structures at the northern edge of the Ionian subduction zone. This sector also includes the Pollino Mts. area, where a seismic sequence of thousands of small to moderate earthquakes has been recorded between spring 2010 and 2013. In this sector a seismic gap was previously hypothesized by paleoseismological evidences associated with the lack of major earthquakes in historical catalogs. To perform the tomographic inversion we selected ca. 3600 earthquakes that have occurred in the last thirty years and recorded by permanent and temporary networks managed by INGV and Calabria University. Using for the first time the Local Tomography Software for passive tomography inversion (LOTOS hereinafter) to crustal analysis in southern Italy, we have computed the distribution of Vp, Vs, and the Vp/Vs ratio. The obtained velocity model, jointly evaluated with results of synthetic modeling, as well as with the hypocenter distribution and geological information, gives us new constraints on the geodynamical and structural knowledge of the study area. The comparison between the shallow tomography sections and surface geology shows good correlation between velocity patterns and the main geological features of the study area. In the upper crust a low-velocity anomaly of P- and S-waves is detectable beneath the Pollino Mts. area and seems to separate the Calabrian and southern Apennines domains, characterized by higher velocities. The distributions of high Vp/Vs ratio, representing strongly fractured rocks with likely high fluid content, clearly correlate with areas of significant seismicity. In the lower crust we detect a clear transition from high to low seismic velocities in correspondence with the Tyrrhenian coast of the study area, which may represent the transition from the thinner Tyrrhenian crust to the thicker one beneath Calabria. In this

  15. The GEISEIR Cruise: Detailed Investigation of the Southeast Indian Ridge Seeking for a Geochemical Scan of the Upper Mantle Structure

    NASA Astrophysics Data System (ADS)

    Hemond, C.; Albarede, F.

    2008-12-01

    Isotopic heterogeneities along mid-ocean ridges reflect the dynamics of the underlying mantle. Present studies on the Mid Atlantic Ridge obtained on a 50 km step sampling (nearly 500 isotopic analyses of Pb, Nd, Hf and Sr) have revealed that they are dominated by a range of wavelengths between 600 and 5 000 km, which we interpret as reflecting the stretching and refolding of ancient lithospheric plates by mantle convection. It is time to go back to the ridges to deepen our knowledge of the fine mantle source structure underneath them. Graham and Lyon coworkers (2006) recently discovered that, along the South-East Indian Ridge (SEIR), Hf isotope compositions of MORB toggle over some 3000 km between two groups of values separated by a prominent gap. We interpret this pattern as reflecting the presence of striations between isotopically distinct mantle sources. The cumulated number of "toggles" is proportional to the distance along the ridge, which demonstrates the Poissonian character of the striation occurrences (random mixing). This GEISEIR cruise aims at further exploring the hypothesis that the unique isotopic patterns observed along the SEIR reveal striations between ancient mantle sources and recycled material. The isotopic analysis of the 150 samples recovered by the cruises Boomerang 6 and Westward 10 between St Paul and the Australia- Antarctica Discordance is completed. We consider, however, that the present sampling (roughly at a 50 km step) is too crude for an efficient spectral analysis of the data set. In order to improve this, the GEISEIR cruise will allow us to fill up a few existing gaps at 50 km intervals between 82 et 89° E but also to sample the ridge with a step of 10 km between 89° et 96° E and a step of 5 km between 96 and 99° E. This will allow us to obtain statistical distributions for isotope compositions and to assess the effect of sample density by a local decimation of the data. This cruise is scheduled for January-February 2009 on

  16. High-resolution measurements of the spatial and temporal scalar structure of a turbulent plume

    NASA Astrophysics Data System (ADS)

    Crimaldi, J. P.; Koseff, J. R.

    Two techniques are described for measuring the scalar structure of turbulent flows. A planar laser-induced fluorescence technique is used to make highly resolved measurements of scalar spatial structure, and a single-point laser-induced fluorescence probe is used to make highly resolved measurements of scalar temporal structure. The techniques are used to measure the spatial and temporal structure of an odor plume released from a low-momentum, bed-level source in a turbulent boundary layer. For the experimental setup used in this study, a spatial resolution of 150μm and a temporal resolution of 1,000Hz are obtained. The results show a wide range of turbulent structures in rich detail; the nature of the structure varies significantly in different regions of the plume.

  17. Detailed quantification of delta subsidence, compaction and interaction with man-made structures: the case of the NCA airport, France

    NASA Astrophysics Data System (ADS)

    Cavalié, O.; Sladen, A.; Kelner, M.

    2015-06-01

    River deltas are dynamic costal systems and their evolutions are closely monitored as it often concentrates vital natural resources for the surrounding areas. Many deltas, worldwide, experience subsidence due to geological processes (sediment loading and compaction) or human activities (groundwater or hydrocarbon extraction, land reclamation). This causes shoreline erosion or wetland loss which represent serious issues for the population. In this study, we investigate the dynamic of the Var delta (France) where reclaimed lands over sea have been built to host the Nice côte d'Azur airport (NCA). Actually, the stability of this infrastructure is a permanent concern since, in 1979, a newly built extension of the runway platform collapsed in the sea, causing important damages. The project of land extension stopped, but the present airport platform is still located on reclaimed land. Factors that can trigger such catastrophic landslide are thought to be linked to the delta activity and the artificial airport platform load. We used, therefore, Envisat InSAR data to measure accurately the ground deformation of the area that includes the Var delta and NCA airport. Combining data from ascending and descending orbits, we estimated the east-west and vertical components of the deformation and obtained very accurate displacement rate (with a 1σ error of 0.25 mm yr-1). We found that nearly all the deformation is vertical and impacts the whole Var delta. The Var valley subsides at a very low rate (0.5-1 mm yr-1) but downstream the subsidence rate increases and a clear jump is observed at the transition with the reclaimed lands (1-2 mm yr-1). On average, the reclaimed lands subside at 3 mm yr-1. Since the subsidence rate increases in correlation with the sediment thickness, we interpret it as the compaction of the delta quaternary sedimentary wedge. In addition, three areas subsides faster (between 5 and 10 mm yr-1), with one calling for more attention as it is the largest and

  18. Detailed quantification of delta subsidence, compaction and interaction with man-made structures: the case of the NCA airport, France

    NASA Astrophysics Data System (ADS)

    Cavalié, O.; Sladen, A.; Kelner, M.

    2015-09-01

    River deltas are dynamic coastal systems and their evolutions are closely monitored as it often concentrates vital natural resources for the surrounding areas. Many deltas worldwide experience subsidence due to geological processes (sediment loading and compaction) or human activities (groundwater or hydrocarbon extraction, land reclamation). This causes shoreline erosion or wetland loss which represent serious issues for the population. In this study we investigate the dynamic of the Var delta (France) where reclaimed lands over sea have been built to host the Nice côte d'Azur airport (NCA). Actually, the stability of this infrastructure is a permanent concern since, in 1979, a newly built extension of the runway platform collapsed in the sea, causing important damages. The project of land extension stopped, but the present airport platform is still located on reclaimed land. Factors that can trigger such catastrophic landslide are thought to be linked to the delta activity and the artificial airport platform load. We used, therefore, Envisat InSAR data to measure accurately the ground deformation of the area that includes the Var delta and NCA airport. Combining data from ascending and descending orbits, we estimated the east-west and vertical components of the deformation and obtained very accurate displacement rate (with a 1σ error of 0.25 mm yr-1). We found that nearly all the deformation is vertical and impacts the whole Var delta. The Var valley subsides at a very low rate (0.5-1 mm yr-1) but downstream the subsidence rate increases and a clear jump is observed at the transition with the reclaimed lands (1-2 mm yr-1). On average, the reclaimed lands subside at 3 mm yr-1. Since the subsidence rate increases in correlation with the sediment thickness, we interpret it as the compaction of the delta quaternary sedimentary wedge. In addition, three areas subside faster (between 5 and 10 mm yr-1), with one calling for more attention as it is the largest and

  19. Crowdsourcing detailed flood data

    NASA Astrophysics Data System (ADS)

    Walliman, Nicholas; Ogden, Ray; Amouzad*, Shahrzhad

    2015-04-01

    Over the last decade the average annual loss across the European Union due to flooding has been 4.5bn Euros, but increasingly intense rainfall, as well as population growth, urbanisation and the rising costs of asset replacements, may see this rise to 23bn Euros a year by 2050. Equally disturbing are the profound social costs to individuals, families and communities which in addition to loss of lives include: loss of livelihoods, decreased purchasing and production power, relocation and migration, adverse psychosocial effects, and hindrance of economic growth and development. Flood prediction, management and defence strategies rely on the availability of accurate information and flood modelling. Whilst automated data gathering (by measurement and satellite) of the extent of flooding is already advanced it is least reliable in urban and physically complex geographies where often the need for precise estimation is most acute. Crowdsourced data of actual flood events is a potentially critical component of this allowing improved accuracy in situations and identifying the effects of local landscape and topography where the height of a simple kerb, or discontinuity in a boundary wall can have profound importance. Mobile 'App' based data acquisition using crowdsourcing in critical areas can combine camera records with GPS positional data and time, as well as descriptive data relating to the event. This will automatically produce a dataset, managed in ArcView GIS, with the potential for follow up calls to get more information through structured scripts for each strand. Through this local residents can provide highly detailed information that can be reflected in sophisticated flood protection models and be core to framing urban resilience strategies and optimising the effectiveness of investment. This paper will describe this pioneering approach that will develop flood event data in support of systems that will advance existing approaches such as developed in the in the UK

  20. Validity of Structure, Coherence, and Quality Measures in Writing.

    ERIC Educational Resources Information Center

    Spencer, Sharon L.; Fitzgerald, Jill

    1993-01-01

    Investigates convergent and divergent validity of inferences from selected measures of structure, coherence, and quality for compositions. Finds (1) strong support for validity of inferences from the structure measures, serious questions of inferences from coherence measures, and weak support for quality measures; (2) some evidence for the…

  1. Validity of Structure, Coherence, and Quality Measures in Writing.

    ERIC Educational Resources Information Center

    Spencer, Sharon L.; Fitzgerald, Jill

    1993-01-01

    Investigates convergent and divergent validity of inferences from selected measures of structure, coherence, and quality for compositions. Finds (1) strong support for validity of inferences from the structure measures, serious questions of inferences from coherence measures, and weak support for quality measures; (2) some evidence for the…

  2. Review of Ship Structural Details

    DTIC Science & Technology

    1977-01-01

    piece may have to be tapered tc assure continuity. 3-103 -*. te *. ’ |g||i||g|j^g —i -■■ -— — ~ ■ - aMUjJwM DECK I- LATINO t SNIPE fi"*li. \\ z...7.1.2 Ail :- ingle bottom vessels are to have center keelsons formed of continuous .ir intercostal center girder plates with horizontal top plates

  3. Measurement Systems Viewed as Cognitive Structures. Final Report.

    ERIC Educational Resources Information Center

    Batchelder, William H.

    This report contains a variety of material. There is first a brief summary of work done under the contract. This is followed by a detailed outline of a graduate seminar entitled "Modern Topics in Measurement and Scaling III." The six major divisions are: (1) introduction and philosophy of measurement; (2) mathematical and axiomatic foundations of…

  4. Measurement Systems Viewed as Cognitive Structures. Final Report.

    ERIC Educational Resources Information Center

    Batchelder, William H.

    This report contains a variety of material. There is first a brief summary of work done under the contract. This is followed by a detailed outline of a graduate seminar entitled "Modern Topics in Measurement and Scaling III." The six major divisions are: (1) introduction and philosophy of measurement; (2) mathematical and axiomatic foundations of…

  5. Geophysical Measurements of Basalt Intraflow Structures.

    DTIC Science & Technology

    1997-12-01

    cliff face just downstream from the Lucky Peak Dam . Visible in outcrop at this location are well developed intraflow structures common to basalt...just downstream from the Lucky Peak Dam . Visible in outcrop at this location are well developed intraflow structures common to basalt flows throughout...Profile and cross section of the Boise River canyon near Lucky Peak Dam 8 Figure 2.3 Well field map 12 Figure 2.4 Magnetic field strength along

  6. Detailed film cooling effectiveness and three component velocity field measurements on a first stage turbine vane subject to high freestream turbulence

    NASA Astrophysics Data System (ADS)

    Polanka, Marcus Damian

    1999-11-01

    This experimental program studied the effects of high freestream turbulence on film cooling for a turbine vane. This investigation focussed on the showerhead and pressure surface of an airfoil. An emphasis of this study was to acquire highly detailed film cooling effectiveness and velocity measurements in the showerhead region. Acquisition of both pieces of information resulted in detailed knowledge of the physics involved in the interaction of the coolant jets and the freestream flow in this region of an airfoil. By generating a 18% turbulence level at the leading edge of the airfoil, the impact of elevated freestream turbulence was also studied. Of further interest was the affect of a highly turbulent flow resulting from both the freestream flow as well as that generated from the showerhead jets themselves, further downstream. The impact of this turbulent approach flow will have significant consequence on downstream film cooling designs. In order to achieve the desired goals, modification to the existing closed loop wind tunnel facility was required. The new tunnel consisted of a test section containing a center, instrumented airfoil with inner and outer walls positioned to match the flow parameters around the center airfoil. The center airfoil was built at a nine times scale ratio. In utilizing this large scale vane and still matching the engine conditions, a better understanding of leading edge film cooling was gained. This was a result of the high spatial resolution of the flow field gained from the large scale of the airfoil. This benefited both the Laser Doppler Velocimeter (LDV) system for velocity measurements and the infrared camera used for thermal field measurements. High effectiveness levels were measured throughout the showerhead region. This was attributed to a build up of coolant along the span of the airfoil. The introduction of a high freestream turbulence level increased the uniformity at the expense of lower overall effectiveness levels

  7. MEASURING DETAILED CHEMICAL ABUNDANCES FROM CO-ADDED MEDIUM-RESOLUTION SPECTRA. I. TESTS USING MILKY WAY DWARF SPHEROIDAL GALAXIES AND GLOBULAR CLUSTERS

    SciTech Connect

    Yang Lei; Peng, Eric W.; Kirby, Evan N.; Guhathakurta, Puragra

    2013-05-01

    The ability to measure metallicities and {alpha}-element abundances in individual red giant branch (RGB) stars using medium-resolution spectra (R Almost-Equal-To 6000) is a valuable tool for deciphering the nature of Milky Way dwarf satellites and the history of the Galactic halo. Extending such studies to more distant systems like Andromeda is beyond the ability of the current generation of telescopes, but by co-adding the spectra of similar stars, we can attain the necessary signal-to-noise ratio (S/N) to make detailed abundance measurements. In this paper, we present a method to determine metallicities and {alpha}-element abundances using the co-addition of medium-resolution spectra. We test the method of spectral co-addition using high-S/N spectra of more than 1300 RGB stars from Milky Way globular clusters and dwarf spheroidal galaxies obtained with the Keck II telescope/DEIMOS spectrograph. We group similar stars using photometric criteria and compare the weighted ensemble average abundances ([Fe/H], [Mg/Fe], [Si/Fe], [Ca/Fe], and [Ti/Fe]) of individual stars in each group with the measurements made on the corresponding co-added spectrum. We find a high level of agreement between the two methods, which permits us to apply this co-added spectra technique to more distant RGB stars, like stars in the M31 satellite galaxies. This paper outlines our spectral co-addition and abundance measurement methodology and describes the potential biases in making these measurements.

  8. Measuring hospital medical staff organizational structure.

    PubMed Central

    Shortell, S M; Getzen, T E

    1979-01-01

    Based on organization theory and the work of Roemer and Friedman, seven dimensions of hospital medical staff organization structure are proposed and examined. The data are based on a 1973 nationwide survey of hospital medical staffs conducted by the American Hospital Association. Factor analysis yielded six relatively independent dimensions supporting a multidimensional view of medical staff organization structure. The six dimensions include 1) Resource Capability, 2) Generalist Physician Contractual Orientation, 3) Communication/Control, 4) Local Staff Orientation, 5) Participation in Decision Making, and 6) Hospital-Based Physician Contractual Orientation. It is suggested that these dimensions can be used to develop an empirical typology of hospital medical staff organization structure and to investigate the relationship between medical staff organization and public policy issues related to cost containment and quality assurance. PMID:511580

  9. Structural Measures to Track the Evolution of SNOMED CT Hierarchies

    PubMed Central

    Wei, Duo; Gu, Huanying (Helen); Perl, Yehoshua; Halper, Michael; Ochs, Christopher; Elhanan, Gai; Chen, Yan

    2015-01-01

    The Systematized Nomenclature of Medicine Clinical Terms (SNOMED CT) is an extensive reference terminology with an attendant amount of complexity. It has been updated continuously and revisions have been released semi-annually to meet users’ needs and to reflect the results of quality assurance (QA) activities. Two measures based on structural features are proposed to track the effects of both natural terminology growth and QA activities based on aspects of the complexity of SNOMED CT. These two measures, called the structural density measure and accumulated structural measure, are derived based on two abstraction networks, the area taxonomy and the partial-area taxonomy. The measures derive from attribute relationship distributions and various concept groupings that are associated with the abstraction networks. They are used to track the trends in the complexity of structures as SNOMED CT changes over time. The measures were calculated for consecutive releases of five SNOMED CT hierarchies, including the Specimen hierarchy. The structural density measure shows that natural growth tends to move a hierarchy’s structure toward a more complex state, whereas the accumulated structural measure shows that QA processes tend to move a hierarchy’s structure toward a less complex state. It is also observed that both the structural density and accumulated structural measures are useful tools to track the evolution of an entire SNOMED CT hierarchy and reveal internal concept migration within it. PMID:26260003

  10. Structural measures to track the evolution of SNOMED CT hierarchies.

    PubMed

    Wei, Duo; Helen Gu, Huanying; Perl, Yehoshua; Halper, Michael; Ochs, Christopher; Elhanan, Gai; Chen, Yan

    2015-10-01

    The Systematized Nomenclature of Medicine Clinical Terms (SNOMED CT) is an extensive reference terminology with an attendant amount of complexity. It has been updated continuously and revisions have been released semi-annually to meet users' needs and to reflect the results of quality assurance (QA) activities. Two measures based on structural features are proposed to track the effects of both natural terminology growth and QA activities based on aspects of the complexity of SNOMED CT. These two measures, called the structural density measure and accumulated structural measure, are derived based on two abstraction networks, the area taxonomy and the partial-area taxonomy. The measures derive from attribute relationship distributions and various concept groupings that are associated with the abstraction networks. They are used to track the trends in the complexity of structures as SNOMED CT changes over time. The measures were calculated for consecutive releases of five SNOMED CT hierarchies, including the Specimen hierarchy. The structural density measure shows that natural growth tends to move a hierarchy's structure toward a more complex state, whereas the accumulated structural measure shows that QA processes tend to move a hierarchy's structure toward a less complex state. It is also observed that both the structural density and accumulated structural measures are useful tools to track the evolution of an entire SNOMED CT hierarchy and reveal internal concept migration within it.

  11. Air Vehicle Integration and Technology Research (AVIATR). Task Order 0023: Predictive Capability for Hypersonic Structural Response and Life Prediction: Phase 2 - Detailed Design of Hypersonic Cruise Vehicle Hot-Structure

    DTIC Science & Technology

    2012-02-01

    Structural Response and Life Prediction: Phase II – Detailed Design of Hypersonic Cruise Vehicle Hot-Structure Rob Quiroz , Jon Embler, Rich Jacobs...5a. CONTRACT NUMBER FA8650-08-D-3857-0023 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 62201F 6. AUTHOR(S) Rob Quiroz , Jon Embler, Rich...officer for the program has been Ms. Genet Stewart. The Boeing team was composed of a core group consisting of Rob Quiroz , Rick Jacobs, George

  12. Details of meiosis

    SciTech Connect

    1993-12-31

    Chapter 18, discusses the details of meiosis, beginning with the structure and number of chiasmata, i.e., the cytological term for two homologous chromosomes forming a bivalent which begin to repel each other until they are held together only at the point of crossing-over. The synaptonemal complex which consists of two lateral elements which contain protein and RNA is also discussed. The chapter concludes with a description of meiosis in polyploids, human meiosis, and the behavior of X and Y chromosomes. 28 refs., 8 figs.

  13. The Convected Kappa Distribution Function at Jupiter: Details from the Voyager and Galileo Missions and a Comparison to Cassini Saturn Measurements

    NASA Astrophysics Data System (ADS)

    Kane, M.; Mitchell, D. G.; Mauk, B.; Carbary, J. F.; Hill, M. E.; Dialynas, K.; Krimigis, S. M.

    2016-12-01

    The Voyager and Galileo Missions allowed detailed measurements of 20 keV-2 MeV hot ion distributions in Jupiter's magnetosphere and beyond using the LECP detector on Voyager and EPD on Galileo. The normalized convected kappa distribution function, with isotropy assumed in the plasma convection frame, has well fit hot ion observed fluxes and thus has produced meaningful and ordered physical plasma parameters including the vector bulk velocity, the characteristic energy (temperature) of the distribution, and the high energy spectral index. The kappa model produces temperatures that indicate expansion and adiabatic cooling of hot ions in the nightside, but not in the dayside. Further, there are significant variations in the plasma parameters with time and local time. There is also a boundary layer present near but within the dawn magnetopause where distribution functions were generated from data analysis of the very distant Voyager 2 crossing of this region. Here the flow is apparently entrained into the magnetosheath flow, but temperatures are hot and consistent with rapid transport of plasma from regions of the magnetosphere closer to Jupiter. These observations have led to the proposal of an empirical model of the general convection pattern at Jupiter. Remarkably, application of the convected kappa distribution model to Saturn using Cassini INCA and CHEMS measurements produces a convection pattern and kappa distribution temperature profiles that are remarkably similar when scaled by the sub-solar magnetopause distance and radial size of the planets.

  14. The Crystal Structure of the Ivy delta4-16:0-ACP Desaturase Reveals Structural Details of the Oxidized Active Site and Potential Determinants of Regioselectivity

    SciTech Connect

    Guy,J.; Whittle, E.; Kumaran, D.; Lindqvist, Y.; Shanklin, J.

    2007-01-01

    The multifunctional acyl-acyl carrier protein (ACP) desaturase from Hedera helix (English ivy) catalyzes the {Delta}{sup 4} desaturation of 16:0-ACP and the{Delta}{sup 9} desaturation of 18:0-ACP and further desaturates{Delta}{sup 9}-16:1 or {Delta}{sup 9}-18:1 to the corresponding {Delta}{sup 4,9} dienes. The crystal structure of the enzyme has been solved to 1.95{angstrom} resolution, and both the iron-iron distance of 3.2{angstrom} and the presence of a {mu}-oxo bridge reveal this to be the only reported structure of a desaturase in the oxidized FeIII-FeIII form. Significant differences are seen between the oxidized active site and the reduced active site of the Ricinus communis (castor) desaturase; His{sup 227} coordination to Fe2 is lost, and the side chain of Glu{sup 224}, which bridges the two iron ions in the reduced structure, does not interact with either iron. Although carboxylate shifts have been observed on oxidation of other diiron proteins, this is the first example of the residue moving beyond the coordination range of both iron ions. Comparison of the ivy and castor structures reveal surface amino acids close to the annulus of the substrate-binding cavity and others lining the lower portion of the cavity that are potential determinants of their distinct substrate specificities. We propose a hypothesis that differences in side chain packing explains the apparent paradox that several residues lining the lower portion of the cavity in the ivy desaturase are bulkier than their equivalents in the castor enzyme despite the necessity for the ivy enzyme to accommodate three more carbons beyond the diiron site.

  15. Ring Details on Display

    NASA Image and Video Library

    2016-11-07

    This view from NASA's Cassini spacecraft showcases some of the amazingly detailed structure of Saturn's rings. The rings are made up of many smaller ringlets that blur together when seen from a distance. But when imaged up close, the rings' structures display quite a bit of variation. Ring scientists are debating the nature of these features -- whether they have always appeared this way or if their appearance has evolved over time. This view looks toward the sunlit side of the rings from about 4 degrees above the ring plane. The image was taken in visible light with the Cassini spacecraft wide-angle camera on Sept. 24, 2016. The view was acquired at a distance of approximately 283,000 miles (456,000 kilometers) from Saturn and at a Sun-Saturn-spacecraft, or phase, angle of 32 degrees. Image scale is 17 miles (27 kilometers) per pixel. http://photojournal.jpl.nasa.gov/catalog/PIA20506

  16. Detailed Structural and Quantitative Analysis Reveals the Spatial Organization of the Cell Walls of in Vivo Grown Mycobacterium leprae and in Vitro Grown Mycobacterium tuberculosis*

    PubMed Central

    Bhamidi, Suresh; Scherman, Michael S.; Jones, Victoria; Crick, Dean C.; Belisle, John T.; Brennan, Patrick J.; McNeil, Michael R.

    2011-01-01

    The cell wall of mycobacteria consists of an outer membrane, analogous to that of Gram-negative bacteria, attached to the peptidoglycan (PG) via a connecting polysaccharide arabinogalactan (AG). Although the primary structure of these components is fairly well deciphered, issues such as the coverage of the PG layer by covalently attached mycolates in the outer membrane and the spatial details of the mycolic acid attachment to the arabinan have remained unknown. It is also not understood how these components work together to lead to the classical acid-fast staining of mycobacteria. Because the majority of Mycobacterium tuberculosis bacteria in established experimental animal infections are acid-fast negative, clearly cell wall changes are occurring. To address both the spatial properties of mycobacterial cell walls and to begin to study the differences between bacteria grown in animals and cultures, the cell walls of Mycobacterium leprae grown in armadillos was characterized and compared with that of M. tuberculosis grown in culture. Most fundamentally, it was determined that the cell wall of M. leprae contained significantly more mycolic acids attached to PG than that of in vitro grown M. tuberculosis (mycolate:PG ratios of 21:10 versus 16:10, respectively). In keeping with this difference, more arabinogalactan (AG) molecules, linking the mycolic acids to PG, were found. Differences in the structures of the AG were also found; the AG of M. leprae is smaller than that of M. tuberculosis, although the same basic structural motifs are retained. PMID:21555513

  17. Detailed structural and quantitative analysis reveals the spatial organization of the cell walls of in vivo grown Mycobacterium leprae and in vitro grown Mycobacterium tuberculosis.

    PubMed

    Bhamidi, Suresh; Scherman, Michael S; Jones, Victoria; Crick, Dean C; Belisle, John T; Brennan, Patrick J; McNeil, Michael R

    2011-07-01

    The cell wall of mycobacteria consists of an outer membrane, analogous to that of gram-negative bacteria, attached to the peptidoglycan (PG) via a connecting polysaccharide arabinogalactan (AG). Although the primary structure of these components is fairly well deciphered, issues such as the coverage of the PG layer by covalently attached mycolates in the outer membrane and the spatial details of the mycolic acid attachment to the arabinan have remained unknown. It is also not understood how these components work together to lead to the classical acid-fast staining of mycobacteria. Because the majority of Mycobacterium tuberculosis bacteria in established experimental animal infections are acid-fast negative, clearly cell wall changes are occurring. To address both the spatial properties of mycobacterial cell walls and to begin to study the differences between bacteria grown in animals and cultures, the cell walls of Mycobacterium leprae grown in armadillos was characterized and compared with that of M. tuberculosis grown in culture. Most fundamentally, it was determined that the cell wall of M. leprae contained significantly more mycolic acids attached to PG than that of in vitro grown M. tuberculosis (mycolate:PG ratios of 21:10 versus 16:10, respectively). In keeping with this difference, more arabinogalactan (AG) molecules, linking the mycolic acids to PG, were found. Differences in the structures of the AG were also found; the AG of M. leprae is smaller than that of M. tuberculosis, although the same basic structural motifs are retained.

  18. Structural Studies of Medicago truncatula Histidinol Phosphate Phosphatase from Inositol Monophosphatase Superfamily Reveal Details of Penultimate Step of Histidine Biosynthesis in Plants.

    PubMed

    Ruszkowski, Milosz; Dauter, Zbigniew

    2016-05-06

    The penultimate enzyme in the histidine biosynthetic pathway catalyzes dephosphorylation of l-histidinol 1-phosphate (HOLP) into l-histidinol. The recently discovered in Arabidopsis thaliana plant-type histidinol phosphate phosphatase (HPP) shares no homology with the two other HPP superfamilies known previously in prokaryotes and resembles myo-inositol monophosphatases (IMPases). In this work, identification of an HPP enzyme from a model legume, Medicago truncatula (MtHPP) was based on the highest sequence identity to A. thaliana enzyme. Biochemical assays confirmed that MtHPP was able to cleave inorganic phosphate from HOLP but not from d-myo-inositol-1-phosphate, the main substrate of IMPases. Dimers of MtHPP, determined by size exclusion chromatography, in the presence of CO2 or formaldehyde form mutual, methylene-bridged cross-links between Lys(158) and Cys(245) residues. Four high resolution crystal structures, namely complexes with HOLP (substrate), l-histidinol (product), and PO4 (3-) (by-product) as well as the structure showing the cross-linking between two MtHPP molecules, provide detailed structural information on the enzyme. Based on the crystal structures, the enzymatic reaction mechanism of IMPases is accustomed to fit the data for MtHPP. The enzymatic reaction, which requires Mg(2+) cations, is catalyzed mainly by amino acid residues from the N-terminal domain. The C-terminal domain, sharing little identity with IMPases, is responsible for the substrate specificity (i.e. allows the enzyme to distinguish between HOLP and d-myo-inositol-1-phosphate). Structural features, mainly the presence of a conserved Asp(246), allow MtHPP to bind HOLP specifically.

  19. Threshold contrast detail detectability measurement of the fluoroscopic image quality of a dynamic solid-state digital x-ray image detector.

    PubMed

    Davies, A G; Cowen, A R; Kengyelics, S M; Bury, R F; Bruijns, T J

    2001-01-01

    Solid-state digital x-ray imaging detectors of flat-panel construction will play an increasingly important role in future medical imaging facilities. Solid-state detectors that will support both dynamic (including fluoroscopic) and radiographic image recording are under active development. The image quality of an experimental solid-state digital x-ray image detector operating in a continuous fluoroscopy mode has been investigated. The threshold contrast detail detectability (TCDD) technique was used to compare the fluoroscopic imaging performance of an experimental dynamic solid-state digital x-ray image detector with that of a reference image intensifier television (IITV) fluoroscopy system. The reference system incorporated Plumbicon TV. Results were presented as a threshold detection index, or H(T)(A), curves. Measurements were made over a range of mean entrance air kerma (EAK) rates typically used in conventional IITV fluoroscopy. At the upper and mid EAK rate range (440 and 220 nGy/s) the solid-state detector outperformed the reference IITV fluoroscopy system as measured by TCDD performance. At the lowest measured EAK rate (104 nGy/s), the solid-state detector produces slightly inferior TCDD performance compared with the reference system. Although not statistically significant at this EAK rate, the difference will increase as EAK is lowered further. Overall the TCDD results and early clinical experiences support the proposition that a current design of dynamic solid-state detector produces image quality competitive with that of modern IITV fluoroscopy systems. These findings encourage the development of compact and versatile universal x-ray imaging systems based upon solid-state detector technology to support R & F and vascular/interventional applications.

  20. Revealing the Detailed Structure of the Galactic Core-Collapse Supernova Remnant G292.0+1.8 with X-Ray Mapping

    NASA Astrophysics Data System (ADS)

    Bhalerao, Jayant; Park, Sangwook; Schenck, Andrew

    2017-01-01

    We present our results on the adaptive-mesh mapping of the chemical composition and thermodynamic parameters of the Galactic core-collapse supernova remnant G292.0+1.8 using our deep Chandra observation. Our maps cover the entire supernova remnant and show the detailed spatial distributions of the metal-rich ejecta, circumstellar medium, and the X-ray pulsar wind nebula-dominated regions. Our results suggest radial and azimuthal variations in the ejecta composition and the thermodynamic parameters, underscoring the rich and complex nature of this text book type supernova remnant. Combining our results from this study and our previous work on the ejecta radial velocity distribution (derived from our Chandra HETG data), we discuss the three dimensional structure of the remnant. Some implications on the nature of the progenitor star and explosion scenarios are discussed.

  1. High-density properties of integral-equation theories of fluids: Universal analytic structure and details for the one-component plasma

    NASA Astrophysics Data System (ADS)

    Rosenfeld, Yaakov

    1986-03-01

    We study the analytic properties of the hypernetted-chain (HNC) and soft-mean-spherical (SMSA) theories in the asymptotic high-density limit (AHDL). The scaling properties of the inverse power potentials lead to the introduction of the SMSA-Ewald functions, which correspond to the ``overlap-volume'' functions for hard spheres. The HNC and SMSA theories for soft interactions, as well as the Percus-Yevick theory for hard spheres, feature the same AHDL analytic structure of the pair correlation functions, which is dictated by the hard-sphere Ewald functions. The general discussion is supplemented by detailed results for the one-component plasma. Implications to the analysis of the density-functional theory, of dense matter, near its exact Thomas-Fermi limit are pointed out.

  2. Thermal Conductivity Measurements of Caged Structural Superconductors

    NASA Astrophysics Data System (ADS)

    Matsuzaki, H.; Hida, K.; Kase, N.; Nakano, T.; Takeda, N.

    Thermal conductivity of Ca3Rh4Sn13 and Sr3Ir4Sn13 were measured in magnetic fields to reveal superconducting state. From magnetic susceptibility χ(T) and electrical resistivity ρ(T) measurements, superconducting transition temperature Tc of Ca3Rh4Sn13 and Sr3Ir4Sn13 is determined to be 8 and 5 K, respectively. Thermal conductivity κ(T) of Ca3Rh4Sn13 indicates that superconducting state is nodeless s-wave, because residual thermal conductivity κ0/T in zero magnetic field is very small. On the other hand, κ(T) of Sr3Ir4Sn13 in zero magnetic field suggests that superconductivity possesses nodal gap rather than full gap. Whether nodal superconducting gap exists or not still remains to be clarified, because there is a possibility that the achieving temperature is insufficient to discuss superconducting state.

  3. Comparing the Performance of Three Land Models in Global C Cycle Simulations: A Detailed Structural Analysis: Structural Analysis of Land Models

    SciTech Connect

    Rafique, Rashid; Xia, Jianyang; Hararuk, Oleksandra; Leng, Guoyong; Asrar, Ghassem; Luo, Yiqi

    2016-04-01

    Land models are valuable tools to understand the dynamics of global carbon (C) cycle. Various models have been developed and used for predictions of future C dynamics but uncertainties still exist. Diagnosing the models’ behaviors in terms of structures can help to narrow down the uncertainties in prediction of C dynamics. In this study three widely used land surface models, namely CSIRO’s Atmosphere Biosphere Land Exchange (CABLE) with 9 C pools, Community Land Model (version 3.5) combined with Carnegie-Ames-Stanford Approach (CLM-CASA) with 12 C pools and Community Land Model (version 4) (CLM4) with 26 C pools were driven by the observed meteorological forcing. The simulated C storage and residence time were used for analysis. The C storage and residence time were computed globally for all individual soil and plant pools, as well as net primary productivity (NPP) and its allocation to different plant components’ based on these models. Remotely sensed NPP and statistically derived HWSD, and GLC2000 datasets were used as a reference to evaluate the performance of these models. Results showed that CABLE exhibited better agreement with referenced C storage and residence time for plant and soil pools, as compared with CLM-CASA and CLM4. CABLE had longer bulk residence time for soil C pools and stored more C in roots, whereas, CLM-CASA and CLM4 stored more C in woody pools due to differential NPP allocation. Overall, these results indicate that the differences in C storage and residence times in three models are largely due to the differences in their fundamental structures (number of C pools), NPP allocation and C transfer rates. Our results have implications in model development and provide a general framework to explain the bias/uncertainties in simulation of C storage and residence times from the perspectives of model structures.

  4. Experimental measurement of structural power flow on an aircraft fuselage

    NASA Technical Reports Server (NTRS)

    Cuschieri, J. M.

    1991-01-01

    An experimental technique is used to measure structural intensity through an aircraft fuselage with an excitation load applied near one of the wing attachment locations. The fuselage is a relatively large structure, requiring a large number of measurement locations to analyze the whole of the structure. For the measurement of structural intensity, multiple point measurements are necessary at every location of interest. A tradeoff is therefore required between the number of measurement transducers, the mounting of these transducers, and the accuracy of the measurements. Using four transducers mounted on a bakelite platform, structural intensity vectors are measured at locations distributed throughout the fuselage. To minimize the errors associated with using the four transducer technique, the measurement locations are selected to be away from bulkheads and stiffeners. Furthermore, to eliminate phase errors between the four transducer measurements, two sets of data are collected for each position, with the orientation of the platform with the four transducers rotated by 180 degrees and an average taken between the two sets of data. The results of these measurements together with a discussion of the suitability of the approach for measuring structural intensity on a real structure are presented.

  5. Measuring and modelling the structure of chocolate

    NASA Astrophysics Data System (ADS)

    Le Révérend, Benjamin J. D.; Fryer, Peter J.; Smart, Ian; Bakalis, Serafim

    2015-01-01

    The cocoa butter present in chocolate exists as six different polymorphs. To achieve the desired crystal form (βV), traditional chocolate manufacturers use relatively slow cooling (<2°C/min). A newer generation of rapid cooling systems has been suggested requiring further understanding of fat crystallisation. To allow better control and understanding of these processes and newer rapid cooling processes, it is necessary to understand both heat transfer and crystallization kinetics. The proposed model aims to predict the temperature in the chocolate products during processing as well as the crystal structure of cocoa butter throughout the process. A set of ordinary differential equations describes the kinetics of fat crystallisation. The parameters were obtained by fitting the model to a set of DSC curves. The heat transfer equations were coupled to the kinetic model and solved using commercially available CFD software. A method using single crystal XRD was developed using a novel subtraction method to quantify the cocoa butter structure in chocolate directly and results were compared to the ones predicted from the model. The model was proven to predict phase change temperature during processing accurately (±1°C). Furthermore, it was possible to correctly predict phase changes and polymorphous transitions. The good agreement between the model and experimental data on the model geometry allows a better design and control of industrial processes.

  6. Oceanic crustal structure from seismic measurements

    NASA Astrophysics Data System (ADS)

    Grevemeyer, Ingo

    2014-05-01

    The primary source of our knowledge of the structure of oceanic crust is the interpretation of seismic refraction experiments. The first classic compilation of seismic data of Raitt (in The Sea, 1963) subdivided the crust into three distinct layers, which have formed the reference basis for seismic profiles for the last decades. Today we know that the upper igneous crust (layer 2) is a region of strong velocity gradients, while the lower crust (layer 3) is relatively homogeneous, although it does show an increase in velocity with depth. Further, the upper crust has been sub-divided the in Layer 2A, composed of extruded basalts, and Layer 2B, formed by basaltic sheeted dikes. The lower crust, or Layer 3, often called the "oceanic layer", is inferred to be composed of gabbros. As crust ages, sediments accumulate on the igneous basement, creating layer 1. The velocity structure of the oceanic crust formed by seafloor spreading is inherently related to the process of mantle melting. The amount of melt produced by adiabatic decompression of the mantle and the composition of the resultant igneous crust depend on the temperature, composition, and water content of the mantle source. Normal oceanic crust with a thickness of 6-7 km and Mid-Ocean Ridge Basalt (MORB) like composition is the result of decompressional melting of a mantle source composed of dry pyrolite with a mantle temperature of ~1300°C. Thus, crustal formation occurs as passive response to seafloor spreading (i.e., passive upwelling). Higher mantle temperatures or compositional anomalies may cause buoyant upwelling of the mantle (i.e. active upwelling). The combination of active upwelling and higher mantle temperatures, or the presence of a more fertile mantle source, will produce larger amounts of melting and, likely, a thicker crust. Steady state mantle melting models can be used to investigate the relationship between mantle temperature, upwelling, and mantle composition on one hand and lower crustal

  7. Structural Implications of new Geologic Mapping and a Detailed Gravity Traverse in the Brooks Range Foothills, Chandler Lake Quadrangle, Northern Alaska

    NASA Astrophysics Data System (ADS)

    Peapples, P. R.; Saltus, R. W.; Swenson, R.; Brown, P. J.

    2005-12-01

    A fold and thrust belt in northern Alaska occupies the structural transition from the imbricate thrust sheets (or allochthons) of the Brooks Range to the North Slope coastal plain. Understanding this complexly deformed zone is critical to hydrocarbon assessment in the state-owned lands south of Prudhoe Bay. New geologic mapping and geophysical studies are focused on this important region. Detailed (1:63,360 scale) geologic mapping along the drainages of Tiglukpuk Creek and the Siksikpuk River documents exposures of deep structural levels and provides important constraints for a structural model of this region. A south-to-north structural transect encompasses the transition from the highly deformed thrust sheets of the Endicott Mountains Allochthon (EMA) at the mountain front to the inferred triangle zone at the Tuktu Escarpment 45 miles to the north. Mississippian Carbonates to Triassic siliciclastics make up the EMA north of the mountain front where there is an abrupt transition in structural style from north-vergent asymmetric overturned folding to gentle warping above shallowly dipping fault ramps. Tiglukpuk Anticline represents a fenster where the EMA is overlain in thrust contact by a melange of more distal Ipnavik River Allochthon (IRA) rocks. Parallel synclinoria contain the Okpikruak siliciclastics of the IRA assemblage and the Brookian syntectonic siliciclastics of the Fortress Mountain formation, carried atop the EMA thrust sheets during the latest phase of deformation. This complex structural style abruptly ends at the Tuktu Escarpment which likely represents a backthrust/triangle zone that places shallow north dipping coarse clastics of the Nanushuk Formation over the less competent and highly deformed Torok shale. The structural complexity and associated steeply dipping strata in the foothills belt were not well imaged by existing conventional seismic data in this region. To provide additional subsurface control, we collected ground station gravity

  8. Measurement of flow velocity profiles in tank structures using the prototype device OCM Pro LR.

    PubMed

    Klepiszewski, K; Teufel, M; Seiffert, S; Henry, E

    2011-01-01

    Generally, studies investigating the treatment efficiency of tank structures for storm water or waste water treatment observe pollutant flows in connection with conditions of hydraulic loading. Further investigations evaluate internal processes in tank structures using computational fluid dynamic (CFD) modelling or lab scale tests. As flow paths inside of tank structures have a considerable influence on the treatment efficiency, flow velocity profile (FVP) measurements can provide a possibility to calibrate CFD models and contribute to a better understanding of pollutant transport processes in these structures. This study focuses on tests carried out with the prototype FVP measurement device OCM Pro LR by NIVUS in a sedimentation tank with combined sewer overflow (CSO) situated in Petange, Luxembourg. The OCM Pro LR measurement system analyses the echo of ultrasonic signals of different flow depths to get a detailed FVP. A comparison of flow velocity measured by OCM Pro LR with a vane measurement showed good conformity. The FVPs measured by OCM Pro LR point out shortcut flows within the tank structure during CSO events, which could cause a reduction of the cleaning efficiency of the structure. The results prove the applicability of FVP measurements in large-scale structures.

  9. Estimating summary measures of health: a structured workbook approach.

    PubMed

    Flanagan, William; Boswell-Purdy, Jane; Le Petit, Christel; Berthelot, Jean-Marie

    2005-05-11

    BACKGROUND: Summary measures of health that combine mortality and morbidity into a single indicator are being estimated in the Canadian context for approximately 200 diseases and conditions. To manage the large amount of data and calculations for this many diseases, we have developed a structured workbook system with easy to use tools. We expect this system will be attractive to researchers from other countries or regions of Canada who are interested in estimating the health-adjusted life years (HALYs) lost to premature mortality and year-equivalents lost to reduced functioning, as well as population attributable fractions (PAFs) associated with risk factors. This paper describes the workbook system using cancers as an example, and includes the entire system as a free, downloadable package. METHODS: The workbook system was developed in Excel and runs on a personal computer. It is a database system that stores data on population structure, mortality, incidence, distributions of cases entering a multitude of health states, durations of time spent in health states, preference scores that weight for severity, life table estimates of life expectancies, and risk factor prevalence and relative risks. The tools are Excel files with embedded macro programs. The main tool generates workbooks that estimate HALY, one per disease, by copying data from the database into a pre-defined template. Other tools summarize the HALY results across diseases for easy analysis. RESULTS: The downloadable zip file contains the database files initialized with Canadian data for cancers, the tools, templates and workbooks that estimate PAF and a user guide. The workbooks that estimate HALY are generated from the system at a rate of approximately one minute per disease. The resulting workbooks are self-contained and can be used directly to explore the details of a particular disease. Results can be discounted at different rates through simple parameter modification. CONCLUSION: The structured

  10. Estimating summary measures of health: a structured workbook approach

    PubMed Central

    Flanagan, William; Boswell-Purdy, Jane; Le Petit, Christel; Berthelot, Jean-Marie

    2005-01-01

    Background Summary measures of health that combine mortality and morbidity into a single indicator are being estimated in the Canadian context for approximately 200 diseases and conditions. To manage the large amount of data and calculations for this many diseases, we have developed a structured workbook system with easy to use tools. We expect this system will be attractive to researchers from other countries or regions of Canada who are interested in estimating the health-adjusted life years (HALYs) lost to premature mortality and year-equivalents lost to reduced functioning, as well as population attributable fractions (PAFs) associated with risk factors. This paper describes the workbook system using cancers as an example, and includes the entire system as a free, downloadable package. Methods The workbook system was developed in Excel and runs on a personal computer. It is a database system that stores data on population structure, mortality, incidence, distributions of cases entering a multitude of health states, durations of time spent in health states, preference scores that weight for severity, life table estimates of life expectancies, and risk factor prevalence and relative risks. The tools are Excel files with embedded macro programs. The main tool generates workbooks that estimate HALY, one per disease, by copying data from the database into a pre-defined template. Other tools summarize the HALY results across diseases for easy analysis. Results The downloadable zip file contains the database files initialized with Canadian data for cancers, the tools, templates and workbooks that estimate PAF and a user guide. The workbooks that estimate HALY are generated from the system at a rate of approximately one minute per disease. The resulting workbooks are self-contained and can be used directly to explore the details of a particular disease. Results can be discounted at different rates through simple parameter modification. Conclusion The structured

  11. Detailed structure of the Philippine Sea plate subducting along the Nankai Trough, western Japan, inferred from high-frequency seismic wave analysis

    NASA Astrophysics Data System (ADS)

    Furumura, T.; Padhy, S.; Maeda, T.

    2012-12-01

    A detailed structure of the subducting Philippine Sea plate (PHP) along the Nankai trough in western Japan was studied by analyzing waveforms recorded at dense Hi-net stations in Japan. It is well recognized that the waveforms from intraplate earthquakes dominate in high-frequency (f >1 Hz) signals due to the waveguide effect of the subducting slab (Furumura and Kennett, 2005; 2008). This results in distorted pattern of intensity and peak ground acceleration (PGA) above the hypocenter with a substantial elongation of isoseismic contours correlated with the configuration of the isodepth contours of the subducting PHP beneath western Japan. A detailed analysis of the dense Hi-net waveform data from the intermediate-depth PHP event shows that the high-frequency S-wave signals suddenly disappear as the waves propagate the zone away from the Kii Channel to the boundary of Hyogo and Okayama prefectures and large S-to-P conversion occurs before the arrival of S-wave. Such anomalies do not occur for shallow and deep earthquakes occurring outside the PHP. These observations support the recent debate on the complexities of the configuration of the PHP subducting beneath western Japan such as that shown by Shiomi et al. (2008) based on receiver function images and the PHP-split model beneath the Kii channel shown by Ide et al.(2010) based on the analysis of comprehensive geophysical data. In order to explain the observations associated with sudden lateral change in the PHP structure, we conducted finite difference method (FDM) simulations of seismic wave propagation taking the detailed PHP model into account. It is confirmed that high-frequency guided wave energy decouple from waveguide where the shape of the PHP is suddenly deformed, which results in dramatic attenuation of high-frequency signals associating with large S-to-P conversions developed at sharp plate boundary. The present results also support the recently proposed complicated PHP-split model, however, further

  12. Measurements of turbulence and vegetation structure across a forest clearing

    NASA Astrophysics Data System (ADS)

    Queck, R.; Bernhofer, C.; Bienert, A.; Maas, H.-G.

    2012-04-01

    Detailed knowledge of the energy and mass exchange between forests and atmosphere is essential for the assessment of carbon sequestration of forests and their capacity for absorption and emission of atmospheric trace gases. Compared to agricultural land uses the vegetation layer of forests is much larger, involves significant currents of air and acts as storage for energy and gases. Advective fluxes within and above a forest canopy occur as a result of the heterogeneity of the soil conditions and the vegetation composition. Turbulent and advective fluxes change with meteorological conditions (e.g. radiation, wind speed and direction) but also with the state of the canopy. The influence of the canopy structure on the fluxes is rarely investigated. To address this topic and to improve the parameterisation of unresolved exchange effects at inhomogeneities in numerical models the TurbEFA experiment was designed. TurbEFA is the acronym for the interdisciplinary project "Turbulent Exchange processes between Forested areas and the Atmosphere", it encompasses the work of five groups applying terrestrial laser scanning, meteorological field measurements, wind tunnel measurements, boundary layer modelling and large eddy simulation. Subject of investigation is the FluxNet site `Anchor Station Tharandt' which is located about 20 km southwest of the city of Dresden in Germany (N 50°57'49", E 13°34'01", 380 m a.s.l.). From May 2008 to May 2009 intensive measurements took place across the forest clearing "Wildacker" in the vicinity of the FluxNet site. Sonic anemometers at 32 measurement positions in total are used to record the turbulent flow at 4 towers (heights: 40m, 40m, 40m, 30m) and five ground level positions (2 m). The forest stands around the clearing (500 m x 60 m) were scanned applying a terrestrial laser scanner. Thereby scans from different ground positions and from the top of two towers (height: 40m) were accomplished. The scans were filtered and combined to a

  13. Dual-scale hydrothermal circulation inferred from detailed heat flow measurements in the Suiyo Seamount Hydrothermal System, Izu-Bonin Arc

    NASA Astrophysics Data System (ADS)

    Gomado, M.; Kinoshita, M.

    2002-12-01

    Hydrothermal activity within the caldera of Suiyo Seamount was investigated in detail using manned or remotely-operated submersibles, and by deep-tow imagery and seismic surveys. Hydrothermal regime in the Suiyo-seamount is characterized by a geochemically uniform fluid, shallow reservoir depth, very permeable seafloor, and venting without creating big chimneys. Detailed heat flow surveys were carried out through four research cruises conducted in 2001-2002. Geothermal probes, called SAHF (Stand-Alone Heat Flow) meter, are 1m in length, and five thermistors are installed at 11-12 cm intervals. Heat flow is highest (> 10 W/m2) within the active area. These values were obtained close to black smokers, thus are affected by the venting or very shallow reservoirs. To the east, heat flow is uniform around 4 W/m2. Since there were no indications of discharge, this area is dominated by thermal conduction, and its heat source would be a hydrothermal reservoir capped by some impermeable layer. To the west, we detected very low heat flow values of less than 0.3 W/m2, only several tens of meters away from the active area. A similar heat flow anomaly was detected in the TAG hyudrothermal mound of the Mid-Atlantic Ridge (Becker et al., 1996). We penetrated at 1-2 m away from two isolated active sulfide mounds. At both sites subbottom temperatures were about 40 degC at 10-20 cm depth, then they decreased to about 20 degC at 30-40cm. The temperature reversals suggest a meter-scale hydrothermal circulation, where a hot fluid discharges as a branch flow from the main vent to the mound. An impermeable structure of the mound and a permeable sediment surrounding the mound would make this very local circulation possible. We suggest a dual scale hydrothermal circulation system, one with several meters scale, and the other with few tens of meters scale. The former would be driven by a suction created by discrete venting of high temperature fluid, and the latter is a regional

  14. The First Crystal Structure of a dTTP-bound Deoxycytidylate Deaminase Validates and Details the Allosteric-Inhibitor Binding Site*

    PubMed Central

    Marx, Ailie; Alian, Akram

    2015-01-01

    Deoxycytidylate deaminase is unique within the zinc-dependent cytidine deaminase family as being allosterically regulated, activated by dCTP, and inhibited by dTTP. Here we present the first crystal structure of a dTTP-bound deoxycytidylate deaminase from the bacteriophage S-TIM5, confirming that this inhibitor binds to the same site as the dCTP activator. The molecular details of this structure, complemented by structures apo- and dCMP-bound, provide insights into the allosteric mechanism. Although the positioning of the nucleoside moiety of dTTP is almost identical to that previously described for dCTP, protonation of N3 in deoxythymidine and not deoxycytidine would facilitate hydrogen bonding of dTTP but not dCTP and may result in a higher affinity of dTTP to the allosteric site conferring its inhibitory activity. Further the functional group on C4 (O in dTTP and NH2 in dCTP) makes interactions with nonconserved protein residues preceding the allosteric motif, and the relative strength of binding to these residues appears to correspond to the potency of dTTP inhibition. The active sites of these structures are also uniquely occupied by dTMP and dCMP resolving aspects of substrate specificity. The methyl group of dTMP apparently clashes with a highly conserved tyrosine residue, preventing the formation of a correct base stacking shown to be imperative for deamination activity. The relevance of these findings to the wider zinc-dependent cytidine deaminase family is also discussed. PMID:25404739

  15. The first crystal structure of a dTTP-bound deoxycytidylate deaminase validates and details the allosteric-inhibitor binding site.

    PubMed

    Marx, Ailie; Alian, Akram

    2015-01-02

    Deoxycytidylate deaminase is unique within the zinc-dependent cytidine deaminase family as being allosterically regulated, activated by dCTP, and inhibited by dTTP. Here we present the first crystal structure of a dTTP-bound deoxycytidylate deaminase from the bacteriophage S-TIM5, confirming that this inhibitor binds to the same site as the dCTP activator. The molecular details of this structure, complemented by structures apo- and dCMP-bound, provide insights into the allosteric mechanism. Although the positioning of the nucleoside moiety of dTTP is almost identical to that previously described for dCTP, protonation of N3 in deoxythymidine and not deoxycytidine would facilitate hydrogen bonding of dTTP but not dCTP and may result in a higher affinity of dTTP to the allosteric site conferring its inhibitory activity. Further the functional group on C4 (O in dTTP and NH2 in dCTP) makes interactions with nonconserved protein residues preceding the allosteric motif, and the relative strength of binding to these residues appears to correspond to the potency of dTTP inhibition. The active sites of these structures are also uniquely occupied by dTMP and dCMP resolving aspects of substrate specificity. The methyl group of dTMP apparently clashes with a highly conserved tyrosine residue, preventing the formation of a correct base stacking shown to be imperative for deamination activity. The relevance of these findings to the wider zinc-dependent cytidine deaminase family is also discussed. © 2015 by The American Society for Biochemistry and Molecular Biology, Inc.

  16. Local Surface Structure From Disparity Measurements

    NASA Astrophysics Data System (ADS)

    Jenkin, Michael R. M.; Jepson, Allan D.; Tsotsos, John K.

    1988-02-01

    Current theories of stereopsis involve three distinct stages: First, the two images of a stereo pair are processed separately to extract monocular features. One common choice of feature is the presence of a zero-crossing in a bandpassed versions of the image. Second, the monocular features in one image are matched with corresponding features found in the other image. In practice this second stage cannot be expected to produce only the correct matches, and a third stage must be considered in order to remove the incorrect matches ("false targets"). There are therefore three main issues the design of such a traditional algorithm for stereopsis, namely i) the choice of image features; the choice of matching criteria; and iii) the way false targets are avoided or eliminated. In this paper we introduce a different approach. We propose that symbolic features should not be extracted from the monocular images in the first stage of processing. Rather we examine a technique for measuring the local phase difference between the two images. We show how local phase difference in a bandpassed version of the image can be interpreted as disparity. This essentially combines the first two stages of the traditional approach. These disparity measurements may contain "false targets" which must be eliminated. Building upon the results of these disparty detectors, we show that a simple surface model based on object cohesiveness and local surface planarity across a range of spatial-frequency tuned channels can be used to reduce false matches. The resulting local planar surface support can be used to segment the image into planar regions in depth. Due to the independent nature of both the disparity detection and local planar support mechanism, this method is capable of dealing with both opaque and transparent stimuli.

  17. Measuring Dynamic Patterns in the Structure of Substate Economies.

    ERIC Educational Resources Information Center

    McHugh, Richard; And Others

    The objective of this study was to explore a new method of analyzing the performance of substate economies. Conventional analyses of economic diversity and growth are limited by their reliance on static measures of economic structure. Such measures do not capture the patterns of growth dynamics or structural change a region may be experiencing.…

  18. Using Hyperspectral Frame Images from Unmanned Airborne Vehicle for Detailed Measurement of Boreal Forest 3D Structure

    NASA Astrophysics Data System (ADS)

    de Oliveira, Raquel A.; Tommaselli, Antonio M. G.; Honkavaara, Eija

    2016-10-01

    Objective of this work was to investigate the feasibility of using multi-image matching and information extracted from image classification to improve strategies in generation of point clouds of 3D forest scene. Image data sets were collected by a Fabry-Pérot interferometer (FPI) based hyperspectral frame camera on-board a UAV in a boreal forest area. The results of the new method are analysed and compared with commercial software and LiDAR data. Experiments showed that the point clouds generated with the proposed algorithm fitted better with the LiDAR data at the ground level, which is favourable for digital terrain model (DTM) extraction.

  19. Wind-tunnel measurements in the wakes of structures

    NASA Technical Reports Server (NTRS)

    Woo, H. G. C.; Peterka, J. A.; Cermak, J. E.

    1977-01-01

    Detailed measurements of longitudinal mean velocity, turbulence intensity, space correlations, and spectra made in the wake of two rectangular scaled models in simulated atmospheric boundary-layer winds are presented. The model buildings were 1:50 scale models of two trailers. Results of a flow visualization study of the wake geometry are analyzed with some singular point theorems. Two hypothetical flow patterns of the detailed wake geometry are proposed. Some preliminary studies of the vortex wake, effects of the model size, model aspect ratios, and boundary layer characteristics on the decay rate and extent of the wake are also presented and discussed.

  20. The devil is in the details (or the surface): impact of surface structure and surface energetics on understanding the behavior of nanomaterials in the environment.

    PubMed

    Mudunkotuwa, Imali A; Grassian, Vicki H

    2011-05-01

    Metal and metal oxide nanomaterials are found in many consumer products for use in a wide range of applications including catalysis, sensors and contaminant remediation. Because of the extensive use of metal-based nanomaterials, there are concerns that these materials have the potential to get into the environment sometime during production, distribution, use and/or disposal. In particular, there exists the potential that they will make their way into water systems, e.g. drinking water systems, ground water systems, estuaries and lakes. In this review, some of the uncertainties in understanding nanoparticle behavior, which is often due to a lack of fundamental knowledge of the surface structure and surface energetics for very small particles, are discussed. Although classical models may provide guidance for understanding dissolution and aggregation of nanoparticles in water, it is the detailed surface structure and surface chemistry that are needed to accurately describe the surface free energy, a large component of the total free energy, in order to fully understand these processes. Without this information, it is difficult to develop a conceptual framework for understanding the fate, transport and potential toxicity of nanomaterials. Needed research areas to fill this void are discussed.

  1. Raman Spectroscopy Adds Complementary Detail to the High-Resolution X-Ray Crystal Structure of Photosynthetic PsbP from Spinacia oleracea

    PubMed Central

    Lapkouski, Mikalai; Hofbauerova, Katerina; Sovova, Zofie; Ettrichova, Olga; González-Pérez, Sergio; Dulebo, Alexander; Kaftan, David; Kuta Smatanova, Ivana; Revuelta, Jose L.; Arellano, Juan B.; Carey, Jannette; Ettrich, Rüdiger

    2012-01-01

    Raman microscopy permits structural analysis of protein crystals in situ in hanging drops, allowing for comparison with Raman measurements in solution. Nevertheless, the two methods sometimes reveal subtle differences in structure that are often ascribed to the water layer surrounding the protein. The novel method of drop-coating deposition Raman spectropscopy (DCDR) exploits an intermediate phase that, although nominally “dry,” has been shown to preserve protein structural features present in solution. The potential of this new approach to bridge the structural gap between proteins in solution and in crystals is explored here with extrinsic protein PsbP of photosystem II from Spinacia oleracea. In the high-resolution (1.98 Å) x-ray crystal structure of PsbP reported here, several segments of the protein chain are present but unresolved. Analysis of the three kinds of Raman spectra of PsbP suggests that most of the subtle differences can indeed be attributed to the water envelope, which is shown here to have a similar Raman intensity in glassy and crystal states. Using molecular dynamics simulations cross-validated by Raman solution data, two unresolved segments of the PsbP crystal structure were modeled as loops, and the amino terminus was inferred to contain an additional beta segment. The complete PsbP structure was compared with that of the PsbP-like protein CyanoP, which plays a more peripheral role in photosystem II function. The comparison suggests possible interaction surfaces of PsbP with higher-plant photosystem II. This work provides the first complete structural picture of this key protein, and it represents the first systematic comparison of Raman data from solution, glassy, and crystalline states of a protein. PMID:23071614

  2. Raman spectroscopy adds complementary detail to the high-resolution x-ray crystal structure of photosynthetic PsbP from Spinacia oleracea.

    PubMed

    Kopecky, Vladimir; Kohoutova, Jaroslava; Lapkouski, Mikalai; Hofbauerova, Katerina; Sovova, Zofie; Ettrichova, Olga; González-Pérez, Sergio; Dulebo, Alexander; Kaftan, David; Smatanova, Ivana Kuta; Revuelta, Jose L; Arellano, Juan B; Carey, Jannette; Ettrich, Rüdiger

    2012-01-01

    Raman microscopy permits structural analysis of protein crystals in situ in hanging drops, allowing for comparison with Raman measurements in solution. Nevertheless, the two methods sometimes reveal subtle differences in structure that are often ascribed to the water layer surrounding the protein. The novel method of drop-coating deposition Raman spectropscopy (DCDR) exploits an intermediate phase that, although nominally "dry," has been shown to preserve protein structural features present in solution. The potential of this new approach to bridge the structural gap between proteins in solution and in crystals is explored here with extrinsic protein PsbP of photosystem II from Spinacia oleracea. In the high-resolution (1.98 Å) x-ray crystal structure of PsbP reported here, several segments of the protein chain are present but unresolved. Analysis of the three kinds of Raman spectra of PsbP suggests that most of the subtle differences can indeed be attributed to the water envelope, which is shown here to have a similar Raman intensity in glassy and crystal states. Using molecular dynamics simulations cross-validated by Raman solution data, two unresolved segments of the PsbP crystal structure were modeled as loops, and the amino terminus was inferred to contain an additional beta segment. The complete PsbP structure was compared with that of the PsbP-like protein CyanoP, which plays a more peripheral role in photosystem II function. The comparison suggests possible interaction surfaces of PsbP with higher-plant photosystem II. This work provides the first complete structural picture of this key protein, and it represents the first systematic comparison of Raman data from solution, glassy, and crystalline states of a protein.

  3. Measuring unconscious knowledge: distinguishing structural knowledge and judgment knowledge.

    PubMed

    Dienes, Zoltán; Scott, Ryan

    2005-06-01

    This paper investigates the dissociation between conscious and unconscious knowledge in an implicit learning paradigm. Two experiments employing the artificial grammar learning task explored the acquisition of unconscious and conscious knowledge of structure (structural knowledge). Structural knowledge was contrasted to knowledge of whether an item has that structure (judgment knowledge). For both structural and judgment knowledge, conscious awareness was assessed using subjective measures. It was found that unconscious structural knowledge could lead to both conscious and unconscious judgment knowledge. When structural knowledge was unconscious, there was no tendency for judgment knowledge to become more conscious over time. Furthermore, conscious rather than unconscious structural knowledge produced more consistent errors in judgments, was facilitated by instructions to search for rules, and after such instructions was harmed by a secondary task. The dissociations validate the use of these subjective measures of conscious awareness.

  4. Detailing the relation between renal T2* and renal tissue pO2 using an integrated approach of parametric magnetic resonance imaging and invasive physiological measurements.

    PubMed

    Pohlmann, Andreas; Arakelyan, Karen; Hentschel, Jan; Cantow, Kathleen; Flemming, Bert; Ladwig, Mechthild; Waiczies, Sonia; Seeliger, Erdmann; Niendorf, Thoralf

    2014-08-01

    This study was designed to detail the relation between renal T2* and renal tissue pO2 using an integrated approach that combines parametric magnetic resonance imaging (MRI) and quantitative physiological measurements (MR-PHYSIOL). Experiments were performed in 21 male Wistar rats. In vivo modulation of renal hemodynamics and oxygenation was achieved by brief periods of aortic occlusion, hypoxia, and hyperoxia. Renal perfusion pressure (RPP), renal blood flow (RBF), local cortical and medullary tissue pO2, and blood flux were simultaneously recorded together with T2*, T2 mapping, and magnetic resonance-based kidney size measurements (MR-PHYSIOL). Magnetic resonance imaging was carried out on a 9.4-T small-animal magnetic resonance system. Relative changes in the invasive quantitative parameters were correlated with relative changes in the parameters derived from MRI using Spearman analysis and Pearson analysis. Changes in T2* qualitatively reflected tissue pO2 changes induced by the interventions. T2* versus pO2 Spearman rank correlations were significant for all interventions, yet quantitative translation of T2*/pO2 correlations obtained for one intervention to another intervention proved not appropriate. The closest T2*/pO2 correlation was found for hypoxia and recovery. The interlayer comparison revealed closest T2*/pO2 correlations for the outer medulla and showed that extrapolation of results obtained for one renal layer to other renal layers must be made with due caution. For T2* to RBF relation, significant Spearman correlations were deduced for all renal layers and for all interventions. T2*/RBF correlations for the cortex and outer medulla were even superior to those between T2* and tissue pO2. The closest T2*/RBF correlation occurred during hypoxia and recovery. Close correlations were observed between T2* and kidney size during hypoxia and recovery and for occlusion and recovery. In both cases, kidney size correlated well with renal vascular conductance

  5. Quantitative characterizations of phasic structure developments by local measurement methods in two-phase flow

    SciTech Connect

    Eberle, C.S.; Leung, W.H.; Wu, Q.; Ueno, T.; Ishii, M.

    1995-06-01

    An experimental study on the internal structure an a out in a 25.4 mm ID pipe. The local void fraction and interfacial area concentration were measured by a double-sensor probe. The flow structure development was visualized by measuring the radial distribution of these two parameters at three axial, locations (L/D = 12, 62, and 112). A more detailed study on the fully developed flow structure was conducted at L/D = 120. The interfacial structure were measured by the double- and four-sensor probes. A bubbly to-=slug transition region was defined according to the local data.The area-averaged void fraction measurements were given by a gamma densitometer. Other parameters such as the Taylor bubble film thickness, bubble length and slug unit length in slug flow were measured by a film robe. The redundant measurements were made to calibrate the local probe measurements. The quantitative representation of the phasic structure can then be used for modeling.

  6. A detailed staging scheme for late larval development in Strongylocentrotus purpuratus focused on readily-visible juvenile structures within the rudiment

    PubMed Central

    2014-01-01

    Background The purple sea urchin, Strongylocentrotus purpuratus, has long been the focus of developmental and ecological studies, and its recently-sequenced genome has spawned a diversity of functional genomics approaches. S. purpuratus has an indirect developmental mode with a pluteus larva that transforms after 1–3 months in the plankton into a juvenile urchin. Compared to insects and frogs, mechanisms underlying the correspondingly dramatic metamorphosis in sea urchins remain poorly understood. In order to take advantage of modern techniques to further our understanding of juvenile morphogenesis, organ formation, metamorphosis and the evolution of the pentameral sea urchin body plan, it is critical to assess developmental progression and rate during the late larval phase. This requires a staging scheme that describes developmental landmarks that can quickly and consistently be used to identify the stage of individual living larvae, and can be tracked during the final two weeks of larval development, as the juvenile is forming. Results Notable structures that are easily observable in developing urchin larvae are the developing spines, test and tube feet within the juvenile rudiment that constitute much of the oral portion of the adult body plan. Here we present a detailed staging scheme of rudiment development in the purple urchin using soft structures of the rudiment and the primordia of these juvenile skeletal elements. We provide evidence that this scheme is robust and applicable across a range of temperature and feeding regimes. Conclusions Our proposed staging scheme provides both a useful method to study late larval development in the purple urchin, and a framework for developing similar staging schemes across echinoderms. Such efforts will have a high impact on evolutionary developmental studies and larval ecology, and facilitate research on this important deuterostome group. PMID:24886415

  7. Structural details of HIV-1 recognition by the broadly neutralizing monoclonal antibody 2F5: epitope conformation, antigen-recognition loop mobility, and anion-binding site.

    PubMed

    Julien, Jean-Philippe; Bryson, Steve; Nieva, Jose L; Pai, Emil F

    2008-12-12

    2F5 is a monoclonal antibody with potent and broadly neutralizing activity against HIV-1. It targets the membrane-proximal external region (MPER) of the gp41 subunit of the envelope glycoprotein and interferes with the process of fusion between viral and host cell membranes. This study presents eight 2F5 F(ab)' crystal structures in complex with various gp41 peptide epitopes. These structures reveal several key features of this antibody-antigen interaction. (1) Whenever free of contacts caused by crystal artifacts, the extended complementarity-determining region H3 loop is mobile; this is true for ligand-free and epitope-bound forms. (2) The interaction between the antibody and the gp41 ELDKWA epitope core is absolutely critical, and there are also close and specific contacts with residues located N-terminal to the epitope core. (3) Residues located at the C-terminus of the gp41 ELDKWA core do not interact as tightly with the antibody. However, in the presence of a larger peptide containing the gp41 fusion peptide segment, these residues adopt a conformation consistent with the start of an alpha-helix. (4) At high sulfate concentrations, the electron density maps of 2F5 F(ab)'-peptide complexes contain a peak that may mark a binding site for phosphate groups of negatively charged lipid headgroups. The refined atomic-level details of 2F5 paratope-epitope interactions revealed here should contribute to a better understanding of the mechanism of 2F5-based virus neutralization, in general, and prove important for the design of potential vaccine candidates intended to elicit 2F5-like antibody production.

  8. Detailed magnetic and structural analysis mapping a robust magnetic C4 dome in Sr1-xNaxFe2As2

    DOE PAGES

    Taddei, K. M.; Allred, J. M.; Bugaris, D. E.; ...

    2016-04-20

    The recently discovered C4 tetragonal magnetic phase in hole-doped members of the iron-based superconductors provides new insights into the origin of unconventional superconductivity. Previously observed in Ba1-xNaxFe2As2 (with A = K, Na), the C4 magnetic phase exists within the well studied C2 spin-density wave (SDW) dome, arising just before the complete suppression of antiferromagnetic (AFM) order but after the onset of superconductivity. Here in this paper, we present detailed x-ray and neutron diffraction studies of Sr1-xNaxFe2As2 (0.10 ≤ x ≤ 0.60) to determine their structural evolution and the extent of the C4 phase. Spanning Δx ~ 0.14 in composition, themore » C4 phase is found to extend over a larger range of compositions, and to exhibit a significantly higher transition temperature, Tr ~ 65K, than in either of the other systems in which it has been observed. The onset of this phase is seen near a composition (x~0:30) where the bonding angles of the Fe2As2 layers approach the perfect 109.46° tetrahedral angle. We discuss the possible role of this return to a higher symmetry environment for the magnetic iron site in triggering the magnetic reorientation and the coupled re-entrance to the tetragonal structure. Finally, we present a new phase diagram, complete with the C4 phase, and use its observation in a third hole-doped 122 system to suggest the universality of this phase.« less

  9. SHOULD THE REORGANIZATION OF ADDICTION-RELATED RESEARCH ACROSS ALL THE NATIONAL INSTITUTES OF HEALTH BE STRUCTURAL?—THE DEVIL IS TRULY IN THE DETAILS

    PubMed Central

    Johnson, Bankole A.; Messing, Robert O.; Charness, Michael E.; Crabbe, John C.; Goldman, Mark S.; Harris, R. Adron; Kranzler, Henry R.; Mitchell, Mack C.; Nixon, Sara Jo; Riley, Edward P.; Schuckit, Marc A.; Sher, Kenneth J.; Thomas, Jennifer D.

    2011-01-01

    The recent proposal to dissolve the National Institute on Alcohol Abuse and Alcoholism and National Institute on Drug Abuse and create a new institute for substance use, abuse, and addiction will require significant effort by the staff of both institutes, the Advisory Councils, and outside experts to overcome complex challenges that could threaten its success. Although integration of the grants portfolios can be achieved, harmonization of goals and policies related to legal use of alcohol versus illegal consumption of drugs will present serious challenges. Consolidating the infrastructure of the two existing institutes would entail avoiding encroachment on grant funding. A new institute for substance use, abuse, and addiction would require an enormous amount of cooperation from other institutes since the portfolios of research on alcohol, tobacco, and other drug abuse should logically be transferred to the new institute. In the near term, a structural reorganization would be less efficient and more costly than the individual institutes are currently. Increasing efficiency and reducing costs over time will necessitate careful strategic planning. Success in this difficult task would be made easier and less costly by first implementing carefully placed building blocks of increasing functional reorganization. The newly created institute should increase opportunities for specialization within disorders of addiction, attract new leadership, and build a novel strategic plan that will energize scientists and staff and incorporate ideas of stakeholders to advance the public good in preventing and treating alcohol, tobacco, and all addictions. Attention must be paid to the devil in the details. PMID:21443646

  10. Should the reorganization of addiction-related research across all the National Institutes of Health be structural?--The devil is truly in the details.

    PubMed

    Johnson, Bankole A; Messing, Robert O; Charness, Michael E; Crabbe, John C; Goldman, Mark S; Harris, R Adron; Kranzler, Henry R; Mitchell, Mack C; Nixon, Sara Jo; Riley, Edward P; Schuckit, Marc A; Sher, Kenneth J; Thomas, Jennifer D

    2011-04-01

    The recent proposal to dissolve the National Institute on Alcohol Abuse and Alcoholism and National Institute on Drug Abuse and create a new institute for substance use, abuse, and addiction will require significant effort by the staff of both institutes, the Advisory Councils, and outside experts to overcome complex challenges that could threaten its success. Although integration of the grants portfolios can be achieved, harmonization of goals and policies related to legal use of alcohol versus illegal consumption of drugs will present serious challenges. Consolidating the infrastructure of the 2 existing institutes would entail avoiding encroachment on grant funding. A new institute for substance use, abuse, and addiction would require an enormous amount of cooperation from other institutes as the portfolios of research on alcohol, tobacco, and other drug abuse should logically be transferred to the new institute. In the near term, a structural reorganization would be less efficient and more costly than the individual institutes are currently. Increasing efficiency and reducing costs over time will necessitate careful strategic planning. Success in this difficult task would be made easier and less costly by first implementing carefully placed building blocks of increasing functional reorganization. The newly created institute should increase opportunities for specialization within disorders of addiction, attract new leadership, and build a novel strategic plan that will energize scientists and staff and incorporate ideas of stakeholders to advance the public good in preventing and treating alcohol, tobacco, and all addictions. Attention must be paid to the devil in the details.

  11. Detailed low-energy electron diffraction analysis of the (4×4) surface structure of C60 on Cu(111): Seven-atom-vacancy reconstruction

    NASA Astrophysics Data System (ADS)

    Xu, Geng; Shi, Xing-Qiang; Zhang, R. Q.; Pai, Woei Wu; Jeng, H. T.; Van Hove, M. A.

    2012-08-01

    A detailed and exhaustive structural analysis by low-energy electron diffraction (LEED) is reported for the C60-induced reconstruction of Cu(111), in the system Cu(111) + (4 × 4)-C60. A wide LEED energy range allows enhanced sensitivity to the crucial C60-metal interface that is buried below the 7-Å-thick molecular layer. The analysis clearly favors a seven-Cu-atom vacancy model (with Pendry R-factor Rp = 0.376) over a one-Cu-atom vacancy model (Rp = 0.608) and over nonreconstructed models (Rp = 0.671 for atop site and Rp = 0.536 for hcp site). The seven-Cu-atom vacancy forms a (4 × 4) lattice of bowl-like holes. In each hole, a C60 molecule can nestle by forming strong bonds (shorter than 2.30 Å) between 15 C atoms of the molecule and 12 Cu atoms of the outermost and second Cu layers.

  12. Determination of Cell Doubling Times from the Return-on-Investment Time of Photosynthetic Vesicles Based on Atomic Detail Structural Models.

    PubMed

    Hitchcock, Andrew; Hunter, C Neil; Sener, Melih

    2017-04-20

    Cell doubling times of the purple bacterium Rhodobacter sphaeroides during photosynthetic growth are determined experimentally and computationally as a function of illumination. For this purpose, energy conversion processes in an intracytoplasmic membrane vesicle, the chromatophore, are described based on an atomic detail structural model. The cell doubling time and its illumination dependence are computed in terms of the return-on-investment (ROI) time of the chromatophore, determined computationally from the ATP production rate, and the mass ratio of chromatophores in the cell, determined experimentally from whole cell absorbance spectra. The ROI time is defined as the time it takes to produce enough ATP to pay for the construction of another chromatophore. The ROI time of the low light-growth chromatophore is 4.5-2.6 h for a typical illumination range of 10-100 μmol photons m(-2) s(-1), respectively, with corresponding cell doubling times of 8.2-3.9 h. When energy expenditure is considered as a currency, the benefit-to-cost ratio computed for the chromatophore as an energy harvesting device is 2-8 times greater than for photovoltaic and fossil fuel-based energy solutions and the corresponding ROI times are approximately 3-4 orders of magnitude shorter for the chromatophore than for synthetic systems.

  13. Characterization of measurement errors using structure-from-motion and photogrammetry to measure marine habitat structural complexity.

    PubMed

    Bryson, Mitch; Ferrari, Renata; Figueira, Will; Pizarro, Oscar; Madin, Josh; Williams, Stefan; Byrne, Maria

    2017-08-01

    Habitat structural complexity is one of the most important factors in determining the makeup of biological communities. Recent advances in structure-from-motion and photogrammetry have resulted in a proliferation of 3D digital representations of habitats from which structural complexity can be measured. Little attention has been paid to quantifying the measurement errors associated with these techniques, including the variability of results under different surveying and environmental conditions. Such errors have the potential to confound studies that compare habitat complexity over space and time. This study evaluated the accuracy, precision, and bias in measurements of marine habitat structural complexity derived from structure-from-motion and photogrammetric measurements using repeated surveys of artificial reefs (with known structure) as well as natural coral reefs. We quantified measurement errors as a function of survey image coverage, actual surface rugosity, and the morphological community composition of the habitat-forming organisms (reef corals). Our results indicated that measurements could be biased by up to 7.5% of the total observed ranges of structural complexity based on the environmental conditions present during any particular survey. Positive relationships were found between measurement errors and actual complexity, and the strength of these relationships was increased when coral morphology and abundance were also used as predictors. The numerous advantages of structure-from-motion and photogrammetry techniques for quantifying and investigating marine habitats will mean that they are likely to replace traditional measurement techniques (e.g., chain-and-tape). To this end, our results have important implications for data collection and the interpretation of measurements when examining changes in habitat complexity using structure-from-motion and photogrammetry.

  14. Establishing a method to measure bone structure using spectral CT

    NASA Astrophysics Data System (ADS)

    Ramyar, M.; Leary, C.; Raja, A.; Butler, A. P. H.; Woodfield, T. B. F.; Anderson, N. G.

    2017-03-01

    Combining bone structure and density measurement in 3D is required to assess site-specific fracture risk. Spectral molecular imaging can measure bone structure in relation to bone density by measuring macro and microstructure of bone in 3D. This study aimed to optimize spectral CT methodology to measure bone structure in excised bone samples. MARS CT with CdTe Medipix3RX detector was used in multiple energy bins to calibrate bone structure measurements. To calibrate thickness measurement, eight different thicknesses of Aluminium (Al) sheets were scanned one in air and the other around a falcon tube and then analysed. To test if trabecular thickness measurements differed depending on scan plane, a bone sample from sheep proximal tibia was scanned in two orthogonal directions. To assess the effect of air on thickness measurement, two parts of the same human femoral head were scanned in two conditions (in the air and in PBS). The results showed that the MARS scanner (with 90μm voxel size) is able to accurately measure the Al (in air) thicknesses over 200μm but it underestimates the thicknesses below 200μm because of partial volume effect in Al-air interface. The Al thickness measured in the highest energy bin is overestimated at Al-falcon tube interface. Bone scanning in two orthogonal directions gives the same trabecular thickness and air in the bone structure reduced measurement accuracy. We have established a bone structure assessment protocol on MARS scanner. The next step is to combine this with bone densitometry to assess bone strength.

  15. Geological Features and Crustal Structure of the Cretaceous Middle Benue Trough, Nigeria: Insights from Detailed Analysis and Modelling of Magnetic and Gravity Data

    NASA Astrophysics Data System (ADS)

    Anudu, G. K.; Stephenson, R.; Macdonald, D.

    2015-12-01

    The middle Benue Trough is the middle (central) segment of the Nigerian Benue Trough, an intra-continental rift that developed during the second phase of rifting of the Gondwana supercontinent that resulted in the opening of the South Atlantic Ocean, Gulf of Guinea and separation of South America from Africa in the Late Jurassic to Early Cretaceous. Airborne magnetic and terrestrial gravity data from the area have been analysed and modelled in detail. Results obtained using a variety of edge enhancement (derivative) methods applied to high-resolution, airborne magnetic data reveal widespread magmatic intrusions (mainly volcanic/sub-volcanic rocks, with an areal extent greater than 12000 km2) and numerous geological structures. Rose (azimuth frequency) plots show that the geological structural trends are predominantly NE - SW, NW - SE and ESE - WNW with minor ENE -WSW/N - S trends and thus suggest that the area has undergone several phases of tectonic deformation at different geological times. Integrated two-dimensional (2-D) gravity and magnetic modelling along five profiles constrained by 2-D magnetic depth-to-source estimates and available seismological velocity models indicates the presence of a number of distinct crustal bodies and thin crust. Moho depth varies from ca. 21 - 29 km, while the crustal thickness ranges between ca. 19 and 29 km. Shallower Moho and thinner crust are observed along the trough axis. Results from the study also reveal that the amount of crustal thinning and crustal stretching factor (β) across the area varies from 3.3 - 14.5 km and 1.11 - 1.78, respectively. Broad positive to near positive Bouguer gravity anomalies in the region of the trough axis are due to the combined effects of dense (intermediate to basic) magmatic intrusions (both intra-sedimentary and intra-basement/crustal ones), shallow basement horsts (basement uplift zones) and thin crust replaced by dense abnormal upper mantle bodies. Reactivated intra-basement structures

  16. Model updating of nonlinear structures from measured FRFs

    NASA Astrophysics Data System (ADS)

    Canbaloğlu, Güvenç; Özgüven, H. Nevzat

    2016-12-01

    There are always certain discrepancies between modal and response data of a structure obtained from its mathematical model and experimentally measured ones. Therefore it is a general practice to update the theoretical model by using experimental measurements in order to have a more accurate model. Most of the model updating methods used in structural dynamics are for linear systems. However, in real life applications most of the structures have nonlinearities, which restrict us applying model updating techniques available for linear structures, unless they work in linear range. Well-established frequency response function (FRF) based model updating methods would easily be extended to a nonlinear system if the FRFs of the underlying linear system (linear FRFs) could be experimentally measured. When frictional type of nonlinearity co-exists with other types of nonlinearities, it is not possible to obtain linear FRFs experimentally by using low level forcing. In this study a method (named as Pseudo Receptance Difference (PRD) method) is presented to obtain linear FRFs of a nonlinear structure having multiple nonlinearities including friction type of nonlinearity. PRD method, calculates linear FRFs of a nonlinear structure by using FRFs measured at various forcing levels, and simultaneously identifies all nonlinearities in the system. Then, any model updating method can be used to update the linear part of the mathematical model. In this present work, PRD method is used to predict the linear FRFs from measured nonlinear FRFs, and the inverse eigensensitivity method is employed to update the linear finite element (FE) model of the nonlinear structure. The proposed method is validated with different case studies using nonlinear lumped single-degree of freedom system, as well as a continuous system. Finally, a real nonlinear T-beam test structure is used to show the application and the accuracy of the proposed method. The accuracy of the updated nonlinear model of the

  17. Measurement and Analysis of Structural Integrity of Reactor Core Support Structure in Pressurized Water Reactor (PWR) Plant

    NASA Astrophysics Data System (ADS)

    Ansari, Saleem A.; Haroon, Muhammad; Rashid, Atif; Kazmi, Zafar

    2017-02-01

    Extensive calculation and measurements of flow-induced vibrations (FIV) of reactor internals were made in a PWR plant to assess the structural integrity of reactor core support structure against coolant flow. The work was done to meet the requirements of the Fukushima Response Action Plan (FRAP) for enhancement of reactor safety, and the regulatory guide RG-1.20. For the core surveillance measurements the Reactor Internals Vibration Monitoring System (IVMS) has been developed based on detailed neutron noise analysis of the flux signals from the four ex-core neutron detectors. The natural frequencies, displacement and mode shapes of the reactor core barrel (CB) motion were determined with the help of IVMS. The random pressure fluctuations in reactor coolant flow due to turbulence force have been identified as the predominant cause of beam-mode deflection of CB. The dynamic FIV calculations were also made to supplement the core surveillance measurements. The calculational package employed the computational fluid dynamics, mode shape analysis, calculation of power spectral densities of flow & pressure fields and the structural response to random flow excitation forces. The dynamic loads and stiffness of the Hold-Down Spring that keeps the core structure in position against upward coolant thrust were also determined by noise measurements. Also, the boron concentration in primary coolant at any time of the core cycle has been determined with the IVMS.

  18. Structures of human sirtuin 3 complexes with ADP-ribose and with carba-NAD+ and SRT1720: binding details and inhibition mechanism.

    PubMed

    Nguyen, Giang Thi Tuyet; Schaefer, Susanne; Gertz, Melanie; Weyand, Michael; Steegborn, Clemens

    2013-08-01

    Sirtuins are NAD(+)-dependent protein deacetylases that regulate metabolism and aging processes and are considered to be attractive therapeutic targets. Most available sirtuin modulators are little understood mechanistically, hindering their improvement. SRT1720 was initially described as an activator of human Sirt1, but it also potently inhibits human Sirt3. Here, the molecular mechanism of the inhibition of Sirt3 by SRT1720 is described. A crystal structure of Sirt3 in complex with SRT1720 and an NAD(+) analogue reveals that the compound partially occupies the acetyl-Lys binding site, thus explaining the reported competition with the peptide substrate. The compound packs against a hydrophobic protein patch and binds with its opposite surface to the NAD(+)  nicotinamide, resulting in an exceptionally tight sandwich-like interaction. The observed arrangement rationalizes the uncompetitive inhibition with NAD(+), and binding measurements confirm that the nicotinamide moiety of NAD(+) supports inhibitor binding. Consistently, no inhibitor is bound in a second crystal structure of Sirt3 that was solved complexed with ADP-ribose and crystallized in the presence of SRT1720. These results reveal a novel sirtuin inhibitor binding site and mechanism, and provide a structural basis for compound improvement.

  19. Pluto's Surface in Detail

    NASA Image and Video Library

    2017-07-14

    On July 14, 2015, NASA's New Horizons spacecraft made its historic flight through the Pluto system. This detailed, high-quality global mosaic of Pluto was assembled from nearly all of the highest-resolution images obtained by the Long-Range Reconnaissance Imager (LORRI) and the Multispectral Visible Imaging Camera (MVIC) on New Horizons. The mosaic is the most detailed and comprehensive global view yet of Pluto's surface using New Horizons data. It includes topography data of the hemisphere visible to New Horizons during the spacecraft's closest approach. The topography is derived from digital stereo-image mapping tools that measure the parallax -- or the difference in the apparent relative positions -- of features on the surface obtained at different viewing angles during the encounter. Scientists use these parallax displacements of high and low terrain to estimate landform heights. The global mosaic has been overlain with transparent, colorized topography data wherever on the surface stereo data is available. Terrain south of about 30°S was in darkness leading up to and during the flyby, so is shown in black. Examples of large-scale topographic features on Pluto include the vast expanse of very flat, low-elevation nitrogen ice plains of Sputnik Planitia ("P") -- note that all feature names in the Pluto system are informal -- and, on the eastern edge of the encounter hemisphere, the aligned, high-elevation ridges of Tartarus Dorsa ("T") that host the enigmatic bladed terrain, mountains, possible cryovolcanos, canyons, craters and more. https://photojournal.jpl.nasa.gov/catalog/PIA21861

  20. Charon's Surface in Detail

    NASA Image and Video Library

    2017-07-14

    On July 14, 2015, NASA's New Horizons spacecraft made its historic flight through the Pluto system. This detailed, high-quality global mosaic of Pluto's largest moon, Charon, was assembled from nearly all of the highest-resolution images obtained by the Long-Range Reconnaissance Imager (LORRI) and the Multispectral Visible Imaging Camera (MVIC) on New Horizons. The mosaic is the most detailed and comprehensive global view yet of Charon's surface using New Horizons data. It includes topography data of the hemisphere visible to New Horizons during the spacecraft's closest approach. The topography is derived from digital stereo-image mapping tools that measure the parallax -- or the difference in the apparent relative positions -- of features on the surface obtained at different viewing angles during the encounter. Scientists use these parallax displacements of high and low terrain to estimate landform heights. The global mosaic has been overlain with transparent, colorized topography data wherever on the surface stereo data is available. Terrain south of about 30°S was in darkness leading up to and during the flyby, so is shown in black. All feature names on Pluto and Charon are informal. The global mosaic has been overlain with transparent, colorized topography data wherever on their surfaces stereo data is available. Standing out on Charon is the Caleuche Chasma ("C") in the far north, an enormous trough at least 350 kilometers (nearly 220 miles) long, and reaching 14 kilometers (8.5 miles) deep -- more than seven times as deep as the Grand Canyon. https://photojournal.jpl.nasa.gov/catalog/PIA21860

  1. Simultaneous dynamic electrical and structural measurements of functional materials

    NASA Astrophysics Data System (ADS)

    Vecchini, C.; Thompson, P.; Stewart, M.; Muñiz-Piniella, A.; McMitchell, S. R. C.; Wooldridge, J.; Lepadatu, S.; Bouchenoire, L.; Brown, S.; Wermeille, D.; Bikondoa, O.; Lucas, C. A.; Hase, T. P. A.; Lesourd, M.; Dontsov, D.; Cain, M. G.

    2015-10-01

    A new materials characterization system developed at the XMaS beamline, located at the European Synchrotron Radiation Facility in France, is presented. We show that this new capability allows to measure the atomic structural evolution (crystallography) of piezoelectric materials whilst simultaneously measuring the overall strain characteristics and electrical response to dynamically (ac) applied external stimuli.

  2. Simultaneous dynamic electrical and structural measurements of functional materials

    SciTech Connect

    Vecchini, C.; Stewart, M.; Muñiz-Piniella, A.; Wooldridge, J.; Thompson, P.; McMitchell, S. R. C.; Bouchenoire, L.; Brown, S.; Wermeille, D.; Lucas, C. A.; Lepadatu, S.; Bikondoa, O.; Hase, T. P. A.; Lesourd, M.; Dontsov, D.; Cain, M. G.

    2015-10-15

    A new materials characterization system developed at the XMaS beamline, located at the European Synchrotron Radiation Facility in France, is presented. We show that this new capability allows to measure the atomic structural evolution (crystallography) of piezoelectric materials whilst simultaneously measuring the overall strain characteristics and electrical response to dynamically (ac) applied external stimuli.

  3. Nickel(II), copper(II) and zinc(II) metallo-intercalators: structural details of the DNA-binding by a combined experimental and computational investigation.

    PubMed

    Lauria, Antonino; Bonsignore, Riccardo; Terenzi, Alessio; Spinello, Angelo; Giannici, Francesco; Longo, Alessandro; Almerico, Anna Maria; Barone, Giampaolo

    2014-04-28

    We present a thorough characterization of the interaction of novel nickel(II) (1), copper(II) (2) and zinc(II) (3) Schiff base complexes with native calf thymus DNA (ct-DNA), in buffered aqueous solution at pH 7.5. UV-vis absorption, circular dichroism (CD) and viscometry titrations provided clear evidence of the intercalative mechanism of the three square-planar metal complexes, allowing us to determine the intrinsic DNA-binding constants (K(b)), equal to 1.3 × 10(7), 2.9 × 10(6), and 6.2 × 10(5) M(-1) for 1, 2 and 3, respectively. Preferential affinity, of one order of magnitude, toward AT compared to GC base pair sequences was detected by UV-vis absorption titrations of 1 with [poly(dG-dC)]2 and [poly(dA-dT)]2. Structural details of the intercalation site of the three metal complexes within [dodeca(dA-dT)]2 were obtained by molecular dynamics (MD) simulations followed by density functional theory/molecular mechanics (DFT/MM) calculations. The calculations revealed that three major intermolecular interactions contribute to the strong affinity between DNA and the three metal complexes: (1) the electrostatic attraction between the two positively charged triethylammoniummethyl groups of the metal complexes and the negatively charged phosphate groups of the DNA backbone; (2) the intercalation of the naphthalene moiety within the four nitrogen bases of the intercalation site; (3) the metal coordination by exocyclic donor atoms of the bases, specifically the carbonyl oxygen and amine nitrogen atoms. Remarkably, the Gibbs formation free energy calculated for the intercalation complexes of 1, 2 and 3 with [dodeca(dA-dT)]2 in the implicit water solution is in agreement with the experimental Gibbs free energy values obtained from the DNA-binding constants as ΔG° = -RT ln(K(b)). In particular, the DNA-binding affinity trend, 1 > 2 > 3, is reproduced. Finally, the first shell coordination distances calculated for the intercalation complex 3/[dodeca(dA-dT)]2 are in

  4. Detailed Gas Chimney Structures in Joetsu Area at Southeastern Margin of Japan Sea, Revealed by High-Resolution 3D Seismic Survey (HR3D)

    NASA Astrophysics Data System (ADS)

    Ohkawa, S.; Hiruta, A.; Yanagimoto, Y.; Matsumoto, R.; Asakawa, E.

    2016-12-01

    To delineate the detailed structure of the gas chimneys, a high-resolution three-dimensional seismic survey (HR3D) was carried out in Joetsu area, at the southeastern margin of Japan Sea where hydrate-related mound and pockmark systems with gas chimneys are widely developed. HR3D data have successfully revealed the fine structure of gas chimneys which were not clearly imaged by the existing seismic data, such as sub-bottom profilers and conventional large-scale 3D surveys for petroleum exploration. HR3D data are also useful to interpolate and extrapolate spatially the geological/geophysical information obtained at wells most of which were drilled into the gas hydrate concentrated zones (GHCZs.) In the areas of low hydrate concentration, the reflections show a parallel-stratified pattern and the bottom simulating reflector (BSR) is parallel to the sea floor reflections. On the other hand, GHCZs are seismologically characterized by (1) strong sea floor reflections on the chimney mounds, (2) chaotic reflection patterns in the chimneys, and (3) pull-up of bottom simulating reflector (BSR) as shown in the attached figure. Strong sea floor reflections suggest that solid hydrates deposit in the very shallow part beneath the sea floor and the chaotic reflections indicate the hydrates are not continuously layered but interspersedly distributed. The BSR pull-up phenomena as much as 70 80msec are caused by high-velocity materials existing between the sea floor and the BSR. The sonic logs acquired by LWD at wells drilled into GHCZs show high velocity up to 3,800 m/s in the massive hydrates. The pull-up times estimated from the sonic data are consistent in general with the observed pull-up times on HR3D sections, suggesting the pull-up times could be useful for a preliminary evaluation of hydrate zones before drilling and/or in the areas without well data. This study was conducted under the commission from AIST as a part of the methane hydrate research project funded by METI

  5. Detailed Structure of Plate Boundary Revealed by Seismic Reflection Survey and Spatial Relation With Interplate Seismic Activity Indicated by Converted Waves, East off Boso Peninsula, Japan

    NASA Astrophysics Data System (ADS)

    Kimura, H.; Kasahara, K.

    2003-12-01

    Tokyo metropolitan area of Japan is located near Sagami trough where Philippine Sea(PHS) plate subducts beneath Kanto district and large earthquakes including Kanto Earthquake, 1923 took place repeatedly. Thus, for the purpose of damage mitigation in Tokyo metropolitan area, it is important to study the characteristics of plate boundary and relation with seismic activity. The area eastern off Boso peninsula is one of regions where interplate earthquakes are occurring at shallower part around Kanto district. We researched the detailed structure of plate boundary and spatial relation with seismic activity using seismic reflection survey data and waveform data of microearthquakes. In this region, multi-channel seismic surveys were conducted by NIED and JNOC(Japan National Oil Corporation). From the analysis of those data (Kimura and Kasahara, 1997; Kimura and Kasahara, 2001), the following results are obtained. 1)There exists clear sediment layer which consists of Quaternary and Tertiary layer(Kazusa, Shimousa and Miura group) with thickness of 0.2 - 2.0 sec in TWT. 2)Major deep reflectors(MDR) have been found dipping northward along the survey line coincident to the plate boundary between PHS plate and landward plate. 3)From the analysis of cross-correlation between reflected waves at acoustic basement and MDR, it is revealed that the polarity of upper reflector is reverse and that of lower is normal. 4)Crustal layer between acoustic basement and MDR is transparent. The candidates of MDR may be the upper and lower boundary of oceanic crust or other surface structure of PHS plate. Taking into consideration polarity of reflectors and results of past survey, it is thought that this layer would correspond to shallowest layer of Izu peninsula with acoustic velocity of 4.1 - 5.0 km/sec and with thickness of 1.0 - 2.0 km revealed by the explosion seismic survey(Asano et al., 1982). In the southern portion of survey line, TWT of MDR is 6.0 - 8.0 sec and suggesting that depth

  6. Evaluation of Strain Measurement Devices for Inflatable Structures

    NASA Technical Reports Server (NTRS)

    Litteken, Doug

    2017-01-01

    Inflatable structures provide a significant volume savings for future NASA deep space missions. The complexity of these structures, however, provides difficulty for engineers in designing, analyzing, and testing. Common strain measurement systems for metallic parts cannot be used directly on fabrics. New technologies must be developed and tested to accurately measure the strain of inflatable structures. This paper documents the testing of six candidate strain measurement devices for use on fabrics. The resistance devices tested showed significant hysteresis during creep and cyclic testing. The capacitive device, however, showed excellent results and little-to-no hysteresis. Because of this issue, only two out of the six proposed devices will continue in development. The resulting data and lessons learned from this effort provides direction for continued work to produce a structural health monitoring system for inflatable habitats.

  7. Simultaneous expansion and orthogonalization of measured modes for structure identification

    NASA Technical Reports Server (NTRS)

    Smith, Suzanne Weaver; Beattie, Christopher A.

    1990-01-01

    Tests of large structures on-orbit will be performed with measurements at a relatively few structure points. Values for the unmeasured degrees of freedom (dofs) can be estimated based on measured dofs and analytical model dynamic information. These 'expanded' mode shapes are useful for optimal-update identification and damage location as well as test/analysis correlation. A new method of expansion for test mode shape vectors is developed from the orthogonal Procrustes problem from computational linear algebra. A subspace defined by the set of measured dofs is compared to a subspace defined by mode shapes from an analytical model of the structure. The method simultaneously expands and orthogonalizes the mode shape vectors. Two demonstration problems are used to compare the new method to current expansion techniques. One demonstration uses test data from a laboratory scale-model truss structure. Performance of the new method is comparable or superior to that of the previous expansion methods which require separate orthogonalization.

  8. Evaluation of Strain Measurement Devices for Inflatable Structures

    NASA Technical Reports Server (NTRS)

    Litteken, Douglas A.

    2017-01-01

    Inflatable structures provide a significant volume savings for future NASA deep space missions. The complexity of these structures, however, provides difficulty for engineers in designing, analyzing, and testing. Common strain measurement systems for metallic parts cannot be used directly on fabrics. New technologies must be developed and tested to accuractly measure the strain of inflatable structures. This paper documents the testing of six candidate strain measurement devices for use on fabrics. The resistance devices tested showed significant hysteresis during creep and cyclic testing. The capacitive device, however, showed excellent results and little-to-no hysteresis. Because of this issue, only two out of the six proposed devices will continue in development. The resulting data and lessons learned from this effort provides direction for continued work to produce a structural health monitoring system for inflatable habitats.

  9. A Detailed 3D Seismic Velocity Structure of the Subducting Pacific Slab Beneath Hokkaido, Tohoku and Kanto, Japan, by Double-Difference Tomography

    NASA Astrophysics Data System (ADS)

    Tsuji, Y.; Nakajima, J.; Kita, S.; Okada, T.; Matsuzawa, T.; Hasegawa, A.

    2007-12-01

    Three-dimensional heterogeneous structure beneath northeastern (NE) Japan has been investigated by previous studies and an inclined seismic low-velocity zone is imaged in the mantle wedge sub-parallel to the down-dip direction of the subducting slab (Zhao et al., 1992, Nakajima et al., 2001). However, the heterogeneous structure within the slab has not been well studied even though it is very important to understand the whole process of water transportation from the slab to the surface. Here we show a detailed 3D seismic velocity structure within the subducted Pacific slab around Japan and propose a water-transportation path from the slab to the mantle wedge. In this study, we estimated 3D velocity structure within the Pacific slab by the double-difference tomography (Zhang and Thurber, 2003). We divided the study area, from Hokkaido to Kanto, into 6 areas due to the limitation of memory and computation time. In each area, arrival-time data of 7,500-17,000 events recorded at 70-170 stations were used in the analysis. The total number of absolute travel-time data was about 140,000-312,000 for P wave and 123,000-268,000 for S wave, and differential data were about 736,000-1,920,000 for P wave and 644,000-1,488,000 for S wave. Horizontal and vertical grid separations are 10-25 km and 6.5 km, respectively. RMS residuals of travel times for P wave decreased from 0.23s to 0.09s and for S wave from 0.35s to 0.13s. The obtained results are as follows: (1) a remarkable low-Vs zone exists in the uppermost part of the subducting slab, (2) it extends down to a depth of about 80 km, (3) the termination of this low-Vs zone almost corresponds to the "seismic belt" recently detected in the upper plane of the double seismic zone (Kita et al.,2006; Hasegawa et al., 2007), (4) at depths deeper than 80 km, a low-Vs and high-Vp/Vs zone is apparently distributed in the mantle wedge, immediately above the slab crust. We consider that these features reflect water-transportation processes

  10. An analysis of source structure effects in radio interferometry measurements

    NASA Technical Reports Server (NTRS)

    Thomas, J. B.

    1980-01-01

    To begin a study of structure effects, this report presents a theoretical framework, proposes an effective position approach to structure corrections based on brightness distribution measurements, and analyzes examples of analytical and measured brightness distributions. Other topics include the effect of the frequency dependence of a brightness distribution on bandwidth synthesis (BWS) delay, the determination of the absolute location of a measured brightness distribution, and structure effects in dual frequency calibration of charged particle delays. For the 10 measured distributions analyzed, it was found that the structure effect in BWS delay at X-band (3.6 cm) can reach 30 cm, but typically falls in the range of 0 to 5 cm. A trial limit equation that is dependent on visibility was successfully tested against the 10 measured brightness distributions (seven sources). If the validity of this particular equation for an upper limit can be established for nearly all sources, the structure effect in BWS delay could be greatly reduced without supplementary measurements of brightness distributions.

  11. Wheel pose measurement based on cross structure light

    NASA Astrophysics Data System (ADS)

    Zhao, Qiancheng; Ding, Xun; Wang, Xian; Zhao, Yafeng

    2016-01-01

    It's necessary for automobile to detect and adjust four-wheel alignment parameters regularly, due to the significant effect on improving stability, enhancing security and reducing tire wear of automobiles. In order to measure the parameters that determined by relative position and posture of four wheels to the automobile cab, this paper proposes a method which applies monocular vision of linear structure light to wheel pose measurement. Firstly, space coordinates of feature point cloud are calculated out from the principle of structured light. Then, an algorithm is designed to determine the normal vector of wheel tangent plane and measure the wheel pose. Finally, actual experiments that by evaluation of adjusted wheel angle measurement are carried out to verify the system accuracy. The corresponding studies can be applied in designing and developing 3D four-wheel alignment system that based on structured light.

  12. Similarity Measure for Molecular Structure: A Brief Review

    NASA Astrophysics Data System (ADS)

    Bero, S. A.; Muda, A. K.; Choo, Y. H.; Muda, N. A.; Pratama, S. F.

    2017-09-01

    Similarity or distance measures have been used widely to calculate the similarity or dissimilarity between two samples of dataset. Cheminformatics is known as the domain that dealing with chemical information and both similarity and distance coefficient have been an important role for matching, searching and classification of chemical information. There are various types of similarity/distance coefficient used in molecular structure similarity searching. Generally, the calculation using similarity/distance coefficient is focusing more on 2-dimensional (2D) rather than 3-dimensional (3D) structure. In this paper, the popular similarity/distance coefficients for molecular structure will be reviewed together with the review on 3D molecular structure.

  13. Development of Oceanic Core Complexes on the Mid-Atlantic Ridge at 13-14N: Deep-Towed Geophysical Measurements and Detailed Seafloor Sampling

    NASA Astrophysics Data System (ADS)

    Searle, R.; MacLeod, C.; Murton, B.; Mallows, C.; Casey, J.; Achenbach, K.; Unsworth, S.; Harris, M.

    2007-12-01

    The first scientific cruise of research vessel James Cook in March-April 2007 targeted the Mid-Atlantic Ridge at 13-14°N, to investigate details of lithospheric generation and development in a low-magmatic setting. Overall objectives were to 1) investigate the 3D pattern of mantle upwelling and melt focusing; 2) study how plate accretion and separation mechanisms differ between magma-rich and magma-poor areas; and 3) test mechanisms of detachment faulting and extensional strain localisation in the lower crust and upper mantle. Smith et al. (Nature 2006) had shown this to be an area of widespread detachment faulting and formation of oceanic core complexes (OCC), and published bathymetry showed an extensive area of blocky rather than lineated topography, which elsewhere has correlated with areas of low effusive magmatism. We conducted a TOBI deep-towed geophysical survey over a 70 km length of ridge extending to magnetic chron C2n (1.9 Ma) on each flank. This included sidescan sonar and high resolution bathymetry and magnetic measurements on 13 E-W tracks spaced 3 - 6 km apart. The area includes 1 active, 1 dying, and 1 defunct OCC and borders well-lineated, apparently magmatically robust seafloor to the north. The geophysical survey was complimented by recovery of 7 oriented and 18 unoriented core and 29 dredge samples, including some from a probable OCC south of the TOBI survey. Deep-towed sidescan, bathymetry and video show the OCCs typically comprise a steeply outward tilted volcanic ridge marking the breakaway (as suggested by Smith et al., 2006); a high, rugged central massif that is complexly deformed as a result of uplift and bending, and may be separated from the breakaway ridge by what we interpret as a late outward dipping normal fault; and a smooth, corrugated surface that generally dips c. 20° towards the ridge axis at the termination but gradually rotates to horizontal or gently outward dipping near its junction with the central massif. Older OCCs

  14. SU-E-T-170: Characterization of the Location, Extent, and Proximity to Critical Structures of Target Volumes Provides Detail for Improved Outcome Predictions Among Pancreatic Cancer Patients

    SciTech Connect

    Cheng, Z; Moore, J; Rosati, L; Mian, O; Narang, A; Herman, J; McNutt, T

    2015-06-15

    Purpose: In radiotherapy, size, location and proximity of the target to critical structures influence treatment decisions. It has been shown that proximity of the target predicts dosimetric sparing of critical structures. In addition to dosimetry, precise location of disease has further implications such as tumor invasion, or proximity to major arteries that inhibit surgery. Knowledge of which patients can be converted to surgical candidates by radiation may have high impact on future treat/no-treat decisions. We propose a method to improve our characterization of the location of pancreatic cancer and treatment volume extent with respect to nearby arteries with the goal of developing features to improve clinical predictions and decisions. Methods: Oncospace is a local learning health system that systematically captures clinical outcomes and all aspects of radiotherapy treatment plans, including overlap volume histograms (OVH) – a measure of spatial relationships between two structures. Minimum and maximum distances of PTV and OARs based on OVH, PTV volume, anatomic location by ICD-9 code, and surgical outcome were queried. Normalized distance to center from the left and right kidney was calculated to indicate tumor location and laterality. Distance to critical arteries (celiac, superior mesenteric, common hepatic) is validated by surgical status (borderline resectable, locally advanced converted to resectable). Results: There were 205 pancreas stereotactic body radiotherapy patients treated from 2009–2015 queried. Location/laterality of tumor based on kidney OVH show strong trends between location by OVH and by ICD-9. Compared to the locally advanced group, the borderline resectable group showed larger geometrical distance from critical arteries (p=0.03). Conclusion: Our platform enabled analysis of shape/size-location relationships. These data suggest that PTV volume and attention to distance between PTVs and surrounding OARs and major arteries may be

  15. Measuring the structure and composition of circumstellar debris disks

    NASA Astrophysics Data System (ADS)

    Ballering, Nicholas Paul

    In this dissertation, I measure the structure and composition of circumstellar debris disks to probe the underlying planetary systems. In Chapter 1, I provide an introduction to the field of debris disks. I highlight our current observational and theoretical understanding of the field, rather than providing a detailed history. This is intended to give the reader context and motivation for the subsequent chapters. I also describe important developments in debris disk science that are not the focus of this dissertation, but are nevertheless vital for a complete overview. In Chapter 2, I describe my analysis of a large sample of cold (<130 K) debris disks seen in Spitzer/IRS data. Previous work had suggested a common temperature for these disk components, regardless of spectral type. I find that there is trend with spectral type and argue that the locations of cold disks are not set by snow lines, but more likely by the formation/evolution of planets. This work was published in Ballering et al. (2013). In Chapter 3, I turn my focus to the warm (˜190 K) debris components identified in Chapter 2--specifically those exhibiting silicate emission features. I show that these features arise from exozodiacal dust in the habitable zones around these stars. This was published in Ballering et al. (2014). In Chapter 4, I examine the remainder of the warm disks to investigate what mechanism sets their location. I find that for many systems, the locations trace the water snow line in the primordial protoplanetary disk, rather than the current snow line. This favors the interpretation that warm debris components arise from asteroid belts in these systems. This study will be published soon. In Chapter 5, I analyze images of the debris disk around beta Pictoris at five different wavelengths, including in thermal emission and scattered light. I find that matching the disk brightness at all wavelengths constrains the composition of the dust, with a mixture of astronomical silicates and

  16. Isotopic quantum effects in water structure measured with high energy photon diffraction

    NASA Astrophysics Data System (ADS)

    Tomberli, B.; Benmore, C. J.; Egelstaff, P. A.; Neuefeind, J.; Honkimäki, V.

    2000-03-01

    High energy electromagnetic radiation scattering techniques have been used to measure the structural differences between light and heavy water: we have studied both intra- and intermolecular effects. These methods and our data analysis are described in detail. We have observed a maximum isotopic effect of 1.6% relative to the magnitude of the x-ray structure factor. Our uncertainties are an order of magnitude smaller than those of previous icons/Journals/Common/gamma" ALT="gamma" ALIGN="TOP"/> -ray measurements (Root J H, Egelstaff P A and Hime A 1986 Chem. Phys. 109 5164) and this has permitted us to test accurately the available quantum simulation results on water. The SPC and TIP4P potentials reproduce the measured results in r -space moderately well for intermolecular effects at distances greater than 2.5 Å. These results show that H2 O is a slightly more disordered liquid than D2 O at the same temperature.

  17. Experimental measurement of structural power flow on an aircraft fuselage

    NASA Technical Reports Server (NTRS)

    Cuschieri, J. M.

    1989-01-01

    An experimental technique is used to measure the structural power flow through an aircraft fuselage with the excitation near the wing attachment location. Because of the large number of measurements required to analyze the whole of an aircraft fuselage, it is necessary that a balance be achieved between the number of measurement transducers, the mounting of these transducers, and the accuracy of the measurements. Using four transducers mounted on a bakelite platform, the structural intensity vectors at locations distributed throughout the fuselage are measured. To minimize the errors associated with using a four transducers technique the measurement positions are selected away from bulkheads and stiffeners. Because four separate transducers are used, with each transducer having its own drive and conditioning amplifiers, phase errors are introduced in the measurements that can be much greater than the phase differences associated with the measurements. To minimize these phase errors two sets of measurements are taken for each position with the orientation of the transducers rotated by 180 deg and an average taken between the two sets of measurements. Results are presented and discussed.

  18. A Vision-Based Sensor for Noncontact Structural Displacement Measurement.

    PubMed

    Feng, Dongming; Feng, Maria Q; Ozer, Ekin; Fukuda, Yoshio

    2015-07-09

    Conventional displacement sensors have limitations in practical applications. This paper develops a vision sensor system for remote measurement of structural displacements. An advanced template matching algorithm, referred to as the upsampled cross correlation, is adopted and further developed into a software package for real-time displacement extraction from video images. By simply adjusting the upsampling factor, better subpixel resolution can be easily achieved to improve the measurement accuracy. The performance of the vision sensor is first evaluated through a laboratory shaking table test of a frame structure, in which the displacements at all the floors are measured by using one camera to track either high-contrast artificial targets or low-contrast natural targets on the structural surface such as bolts and nuts. Satisfactory agreements are observed between the displacements measured by the single camera and those measured by high-performance laser displacement sensors. Then field tests are carried out on a railway bridge and a pedestrian bridge, through which the accuracy of the vision sensor in both time and frequency domains is further confirmed in realistic field environments. Significant advantages of the noncontact vision sensor include its low cost, ease of operation, and flexibility to extract structural displacement at any point from a single measurement.

  19. A Vision-Based Sensor for Noncontact Structural Displacement Measurement

    PubMed Central

    Feng, Dongming; Feng, Maria Q.; Ozer, Ekin; Fukuda, Yoshio

    2015-01-01

    Conventional displacement sensors have limitations in practical applications. This paper develops a vision sensor system for remote measurement of structural displacements. An advanced template matching algorithm, referred to as the upsampled cross correlation, is adopted and further developed into a software package for real-time displacement extraction from video images. By simply adjusting the upsampling factor, better subpixel resolution can be easily achieved to improve the measurement accuracy. The performance of the vision sensor is first evaluated through a laboratory shaking table test of a frame structure, in which the displacements at all the floors are measured by using one camera to track either high-contrast artificial targets or low-contrast natural targets on the structural surface such as bolts and nuts. Satisfactory agreements are observed between the displacements measured by the single camera and those measured by high-performance laser displacement sensors. Then field tests are carried out on a railway bridge and a pedestrian bridge, through which the accuracy of the vision sensor in both time and frequency domains is further confirmed in realistic field environments. Significant advantages of the noncontact vision sensor include its low cost, ease of operation, and flexibility to extract structural displacement at any point from a single measurement. PMID:26184197

  20. Horizontal Cross Bracing Detail, Vertical Cross Bracing Detail, Horizontal Cross ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Horizontal Cross Bracing Detail, Vertical Cross Bracing Detail, Horizontal Cross Bracing Detail, Vertical Cross Bracing-End Detail - Cumberland Covered Bridge, Spanning Mississinewa River, Matthews, Grant County, IN

  1. A Detailed Developmental and Structural Study of the Transcriptional Effects of Insertion of the COPIA Transposon into the White Locus of DROSOPHILA MELANOGASTER

    PubMed Central

    Zachar, Zuzana; Davison, Dan; Garza, Dan; Bingham, Paul M.

    1985-01-01

    The copia insertion responsible for the wa mutation is 3' to the white promotor and in the same transcriptional orientation as white. First, we have analyzed the effects of the w a copia insertion on levels of polyadenylated white transcripts and find large, developmentally programmed effects. Second, we have isolated and sequenced an LTR-excision event involving the copia insertion at wa. This represents the first documented case of an LTR-excision event in Drosophila. This single copia LTR has developmentally programmed effects on white transcript levels qualitatively similar to the intact copia element. Third, we have characterized the structures of white transcripts from wa. We find polyadenylated white transcripts apparently having 3' termini in or near the 3' LTR of the wa copia insertion, as has been reported in limited studies of wa transcription in adults by others. These earlier studies also revealed wa transcripts apparently corresponding to polyadenylated terminus formation in the 5' LTR of the copia transposon; however, our more detailed studies reveal that these transcripts probably have other origins and that little, if any, polyadenylated terminus formation for white transcripts occurs in the 5' LTR of the wa copia insertion. Moreover, we find no polyadenylated terminus formation for white transcripts occurring in the single LTR of the wa LTR-excision product. Fourth, we find that each of three mutant alleles at su(wa) produces elevated levels of several classes of RNAs apparently corresponding to transcriptional readthrough of the wa copia transposon. Elevated levels of one presumptive readthrough transcript were observed previously in one su(w a)1 mutant strain. Fifth, we have confirmed the existence of a transcript initiated in the 3' LTR of the wa copia insertion and find the levels of this transcript to be strongly influenced by developmental stage and genetic background. Lastly, we have analyzed white transcripts produced by the whd81b11

  2. Dynamics of entropic measurement-induced nonlocality in structured reservoirs

    SciTech Connect

    Hu, Ming-Liang; Fan, Heng

    2012-09-15

    We propose the entropic measurement-induced nonlocality (MIN) as the maximal increment of von Neumann entropy induced by the locally non-disturbing measurement, and study its behaviors in both the independent and common structured reservoirs. We present schemes for preserving the MIN, and show that for certain initial states the MIN, including the quantum correlations, can even be enhanced by the common reservoir. Additionally, we also show that the different measures of MIN may give different qualitative characterizations of nonlocal properties, i.e., it is rather measure dependent than state dependent. - Highlights: Black-Right-Pointing-Pointer Features of the entropic measurement-induced nonlocality (MIN). Black-Right-Pointing-Pointer Comparison of MIN with other quantum correlation measures. Black-Right-Pointing-Pointer Enhancement of MIN and other quantum correlations by common reservoir. Black-Right-Pointing-Pointer Relativity of the geometric and entropic MIN measures.

  3. Estimating discharged plutonium using measurements of structural material activation products

    SciTech Connect

    Charlton, W. S.; Lumley-Woodyear, A. de; Budlong-Sylvester, K. W.

    2002-01-01

    As the US and Russia move to lower numbers of deployed nuclear weapons, transparency regarding the quantity of weapons usable fissile material available in each country may become more important. In some cases detailed historical information regarding material production at individual facilities may be incomplete or not readily available, e.g., at decommissioned facilities. In such cases tools may be needed to produce estimates of aggregate material production as part of a bilateral agreement. Such measurement techniques could also provide increased confidence in declared production quantities.

  4. GS-align for glycan structure alignment and similarity measurement

    PubMed Central

    Lee, Hui Sun; Jo, Sunhwan; Mukherjee, Srayanta; Park, Sang-Jun; Skolnick, Jeffrey; Lee, Jooyoung; Im, Wonpil

    2015-01-01

    Motivation: Glycans play critical roles in many biological processes, and their structural diversity is key for specific protein-glycan recognition. Comparative structural studies of biological molecules provide useful insight into their biological relationships. However, most computational tools are designed for protein structure, and despite their importance, there is no currently available tool for comparing glycan structures in a sequence order- and size-independent manner. Results: A novel method, GS-align, is developed for glycan structure alignment and similarity measurement. GS-align generates possible alignments between two glycan structures through iterative maximum clique search and fragment superposition. The optimal alignment is then determined by the maximum structural similarity score, GS-score, which is size-independent. Benchmark tests against the Protein Data Bank (PDB) N-linked glycan library and PDB homologous/non-homologous N-glycoprotein sets indicate that GS-align is a robust computational tool to align glycan structures and quantify their structural similarity. GS-align is also applied to template-based glycan structure prediction and monosaccharide substitution matrix generation to illustrate its utility. Availability and implementation: http://www.glycanstructure.org/gsalign. Contact: wonpil@ku.edu Supplementary information: Supplementary data are available at Bioinformatics online. PMID:25857669

  5. A fingerprint based metric for measuring similarities of crystalline structures

    SciTech Connect

    Zhu, Li; Fuhrer, Tobias; Schaefer, Bastian; Grauzinyte, Migle; Goedecker, Stefan; Amsler, Maximilian; Faraji, Somayeh; Rostami, Samare; Ghasemi, S. Alireza; Sadeghi, Ali; Wolverton, Chris

    2016-01-21

    Measuring similarities/dissimilarities between atomic structures is important for the exploration of potential energy landscapes. However, the cell vectors together with the coordinates of the atoms, which are generally used to describe periodic systems, are quantities not directly suitable as fingerprints to distinguish structures. Based on a characterization of the local environment of all atoms in a cell, we introduce crystal fingerprints that can be calculated easily and define configurational distances between crystalline structures that satisfy the mathematical properties of a metric. This distance between two configurations is a measure of their similarity/dissimilarity and it allows in particular to distinguish structures. The new method can be a useful tool within various energy landscape exploration schemes, such as minima hopping, random search, swarm intelligence algorithms, and high-throughput screenings.

  6. A fingerprint based metric for measuring similarities of crystalline structures.

    PubMed

    Zhu, Li; Amsler, Maximilian; Fuhrer, Tobias; Schaefer, Bastian; Faraji, Somayeh; Rostami, Samare; Ghasemi, S Alireza; Sadeghi, Ali; Grauzinyte, Migle; Wolverton, Chris; Goedecker, Stefan

    2016-01-21

    Measuring similarities/dissimilarities between atomic structures is important for the exploration of potential energy landscapes. However, the cell vectors together with the coordinates of the atoms, which are generally used to describe periodic systems, are quantities not directly suitable as fingerprints to distinguish structures. Based on a characterization of the local environment of all atoms in a cell, we introduce crystal fingerprints that can be calculated easily and define configurational distances between crystalline structures that satisfy the mathematical properties of a metric. This distance between two configurations is a measure of their similarity/dissimilarity and it allows in particular to distinguish structures. The new method can be a useful tool within various energy landscape exploration schemes, such as minima hopping, random search, swarm intelligence algorithms, and high-throughput screenings.

  7. Confocal stereology: an efficient tool for measurement of microscopic structures.

    PubMed

    Kubínová, Lucie; Janáček, Jiří

    2015-04-01

    Quantitative measurements of geometric forms or counting of objects in microscopic specimens is an essential tool in studies of microstructure. Confocal stereology represents a contemporary approach to the evaluation of microscopic structures by using a combination of stereological methods and confocal microscopy. 3-D images acquired by confocal microscopy can be used for the estimation of geometrical characteristics of microscopic structures by stereological methods, based on the evaluation of optical sections within a thick slice and using computer-generated virtual test probes. Such methods can be used for estimating volume, number, surface area and length using relevant spatial probes, which are generated by specific software. The interactions of the probes with the structure under study are interactively evaluated. An overview of the methods of confocal stereology developed during the past 30 years is presented. Their advantages and pitfalls in comparison with other methods for measurement of geometrical characteristics of microscopic structures are discussed.

  8. Pipelines subject to slow landslide movements: Structural modeling vs field measurement

    SciTech Connect

    Bruschi, R.; Glavina, S.; Spinazze, M.; Tomassini, D.; Bonanni, S.; Cuscuna, S.

    1996-12-01

    In recent years finite element techniques have been increasingly used to investigate the behavior of buried pipelines subject to soil movements. The use of these tools provides a rational basis for the definition of minimum wall thickness requirements in landslide crossings. Furthermore the design of mitigation measures or monitoring systems which control the development of undesirable strains in the pipe wall over time, requires a detailed structural modeling. The scope of this paper is to discuss the use of dedicated structural modeling with relevant calibration to field measurements. The strain measurements used were regularly gathered from pipe sections, in two different sites over a period of time long enough to record changes of axial strain due to soil movement. Detailed structural modeling of pipeline layout in both sites and for operating conditions, is applied. Numerical simulations show the influence of the distribution of soil movement acting on the pipeline with regards to the state of strain which can be developed in certain locations. The role of soil nature and direction of relative movements in the definition of loads transferred to the pipeline, is also discussed.

  9. Beam-cavity interaction measurements in a DAW structure

    SciTech Connect

    Iwashita, Y.; Schriber, S.O.; Potter, J.M.; Swenson, D.A.; Mavrogenes, G.S.

    1985-01-01

    Mode excitations induced by relativistic electron beams have been measured in a disk-and-washer (DAW) structure. The structure had three washers, each with four radial support stems, and half-disk end terminations. The design DAW operating frequency was 1300 MHz, the same as that used to accelerate the electron beam. Both short-pulse (35-ps, 800-Hz, 17-nC/pulse) and long-pulse (10-..mu..s, 2-A average) conditions were used in the beam-excitation experiments. Mode spectra were measured and identified using low-power techniques employed after the high-power beam measurements. Mode frequency calculations for the complete three-washer geometry were performed using URMEL for up to m = 7. Calculated results are compared with data determined from low-power and beam-driven excitation of the DAW structure. 5 refs., 2 figs.

  10. Beam-cavity interaction measurements in a DAW structure

    SciTech Connect

    Iwashita, Y.; Mavrogenes, G.S.; Potter, J.M.; Schriber, S.O.; Swenson, D.A.

    1985-10-01

    Mode excitations induced by relativistic electron beams have been measured in a disk-and-washer (DAW) structure. The structure had three washers, each with four radial support stems, and half-disk end terminations. The design DAW operating frequency was 1300 MHz, the same as that used to accelerate the electron beam. Both short-pulse (35-ps, 800-Hz, 17-nC/pulse) and long-pulse (10-..mu..s, 2-A average) conditions were used in the beam-excitation experiments. Mode spectra were measured and identified using lowpower techniques employed after the high-power beam measurements. Mode frequency calculations for the complete three-washer geometry were performed using URMEL for up to m = 7. Calculated results are compared with data determined from low-power and beamdriven excitation of the DAW structure.

  11. Beam-cavity interaction measurements in a DAW structure

    NASA Astrophysics Data System (ADS)

    Iwashita, Y.; Schriber, S. O.; Potter, J. M.; Swenson, D. A.; Mavrogenes, G. S.

    Mode excitations induced by relativistic electron beams have been measured in a disk and washer (DAW) structure. The structure had three washers, each with four radial support stems, and half disk end terminations. The design DAW operating frequency was 1300 MHz, the same as that used to accelerate the electron beam. Both short pulse (35-ps, 800-Hz, 17-nC/pulse) and long pulse (10-(MU)s, 2-A average) conditions were used in the beam excitation experiments. Mode spectra were measured and identified using low power techniques employed after the high power beam measurements. Mode frequency calculations for the complete three washer geometry were performed using URMEL for up to m = 7. Calculated results are compared with data determined from low power and beam driven excitation of the DAW structure.

  12. The refined 1.9-A X-ray crystal structure of D-Phe-Pro-Arg chloromethylketone-inhibited human alpha-thrombin: structure analysis, overall structure, electrostatic properties, detailed active-site geometry, and structure-function relationships.

    PubMed Central

    Bode, W.; Turk, D.; Karshikov, A.

    1992-01-01

    Thrombin is a multifunctional serine proteinase that plays a key role in coagulation while exhibiting several other key cellular bioregulatory functions. The X-ray crystal structure of human alpha-thrombin was determined in its complex with the specific thrombin inhibitor D-Phe-Pro-Arg chloromethylketone (PPACK) using Patterson search methods and a search model derived from trypsinlike proteinases of known spatial structure (Bode, W., Mayr, I., Baumann, U., Huber, R., Stone, S.R., & Hofsteenge, J., 1989, EMBO J. 8, 3467-3475). The crystallographic refinement of the PPACK-thrombin model has now been completed at an R value of 0.156 (8 to 1.92 A); in particular, the amino- and the carboxy-termini of the thrombin A-chain are now defined and all side-chain atoms localized; only proline 37 was found to be in a cis-peptidyl conformation. The thrombin B-chain exhibits the characteristic polypeptide fold of trypsinlike serine proteinases; 195 residues occupy topologically equivalent positions with residues in bovine trypsin and 190 with those in bovine chymotrypsin with a root-mean-square (r.m.s.) deviation of 0.8 A for their alpha-carbon atoms. Most of the inserted residues constitute novel surface loops. A chymotrypsinogen numbering is suggested for thrombin based on the topological equivalences. The thrombin A-chain is arranged in a boomeranglike shape against the B-chain globule opposite to the active site; it resembles somewhat the propeptide of chymotrypsin(ogen) and is similarly not involved in substrate and inhibitor binding. Thrombin possesses an exceptionally large proportion of charged residues. The negatively and positively charged residues are not distributed uniformly over the whole molecule, but are clustered to form a sandwichlike electrostatic potential; in particular, two extended patches of mainly positively charged residues occur close to the carboxy-terminal B-chain helix (forming the presumed heparin-binding site) and on the surface of loop segment 70

  13. Structural Measures for Network Biology Using QuACN

    PubMed Central

    2011-01-01

    Background Structural measures for networks have been extensively developed, but many of them have not yet demonstrated their sustainably. That means, it remains often unclear whether a particular measure is useful and feasible to solve a particular problem in network biology. Exemplarily, the classification of complex biological networks can be named, for which structural measures are used leading to a minimal classification error. Hence, there is a strong need to provide freely available software packages to calculate and demonstrate the appropriate usage of structural graph measures in network biology. Results Here, we discuss topological network descriptors that are implemented in the R-package QuACN and demonstrate their behavior and characteristics by applying them to a set of example graphs. Moreover, we show a representative application to illustrate their capabilities for classifying biological networks. In particular, we infer gene regulatory networks from microarray data and classify them by methods provided by QuACN. Note that QuACN is the first freely available software written in R containing a large number of structural graph measures. Conclusion The R package QuACN is under ongoing development and we add promising groups of topological network descriptors continuously. The package can be used to answer intriguing research questions in network biology, e.g., classifying biological data or identifying meaningful biological features, by analyzing the topology of biological networks. PMID:22195644

  14. Measuring Form Factors and Structure Functions with CLAS

    SciTech Connect

    G.P. Gilfoyle

    2007-09-10

    The physics program at the Thomas Jefferson National Accelerator Facility includes a strong effort to measure form factors and structure functions to probe the structure of hadronic matter, reveal the nature of confinement, and develop an understanding of atomic nuclei using quark-gluon degrees of freedom. The CLAS detector is a large acceptance device occupying one of the end stations. We discuss here two programs that use CLAS; measuring the magnetic form factor of the neutron and the virtual photon asymmetry of the proton. The form factor has been measured with unprecedented kinematic coverage and precision up to Q2=4.7 GeV2 and is consistent within 5%-10% of the dipole parameterization. The proton virtual photon asymmetry has been measured across a wide range in Bjorken x. The data exceed the SU(6)-symmetric quark prediction and show evidence of a smooth approach to the scaling limit prescribed by perturbative QCD.

  15. One Single Static Measurement Predicts Wave Localization in Complex Structures.

    PubMed

    Lefebvre, Gautier; Gondel, Alexane; Dubois, Marc; Atlan, Michael; Feppon, Florian; Labbé, Aimé; Gillot, Camille; Garelli, Alix; Ernoult, Maxence; Mayboroda, Svitlana; Filoche, Marcel; Sebbah, Patrick

    2016-08-12

    A recent theoretical breakthrough has brought a new tool, called the localization landscape, for predicting the localization regions of vibration modes in complex or disordered systems. Here, we report on the first experiment which measures the localization landscape and demonstrates its predictive power. Holographic measurement of the static deformation under uniform load of a thin plate with complex geometry provides direct access to the landscape function. When put in vibration, this system shows modes precisely confined within the subregions delineated by the landscape function. Also the maxima of this function match the measured eigenfrequencies, while the minima of the valley network gives the frequencies at which modes become extended. This approach fully characterizes the low frequency spectrum of a complex structure from a single static measurement. It paves the way for controlling and engineering eigenmodes in any vibratory system, especially where a structural or microscopic description is not accessible.

  16. Detailed Evaluation of the Geometric and Electronic Structures of One-electron Oxidized Group 10 (Ni, Pd, and Pt) Metal(II)-(Disalicylidene)diamine Complexes

    PubMed Central

    Stack, T. Daniel P.

    2009-01-01

    The geometric and electronic structures of a series of one-electron oxidized group 10 metal salens (Ni, Pd, Pt) have been investigated in solution and in the solid state. Ni (1) and Pd (2) complexes of the tetradentate salen ligand N,N’-bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediamine (H2Salcn) have been examined along with the Pt (3) complex of the salen ligand N,N’-bis(3,5-di-tert-butylsalicylidene)-1,2-ethylenediamine (H2Salen). All three oxidized compounds exist as ligand radical species in solution and in the solid state. The solid state structures of [1]+ and [3]+ exhibit a symmetric coordination sphere contraction relative to the neutral forms. By contrast, the coordination sphere of the Pd derivative [2]+ exhibits a pronounced asymmetry in the solid state. In solution, the oxidized derivatives display intense low-energy NIR transitions consistent with their classification as ligand radical compounds. Interestingly, the degree of communication between the phenolate moieties depends strongly on the central metal ion, within the Ni, Pd, and Pt series. Electrochemical measurements and UV-Vis-NIR spectroscopy, in conjunction with DFT calculations provide insights into the degree of delocalization of the one-electron hole in these systems. The Pd complex [2]+ is the least delocalized and is best described as a borderline Class II/III intervalence complex based on the Robin-Day classification system. The Ni [1]+ and Pt [3]+ analogues are Class III (fully delocalized) intervalence compounds. Delocalization is dependent on the electronic coupling between the redox-active phenolate ligands, mediated by overlap between the formally filled metal dxz orbital and the appropriate ligand molecular orbital. The degree of coupling increases in the order Pd < Ni < Pt for the one-electron oxidized group 10 metal salens. PMID:19639970

  17. Detailed evaluation of the geometric and electronic structures of one-electron oxidized group 10 (Ni, Pd, and Pt) metal(II)-(disalicylidene)diamine complexes.

    PubMed

    Shimazaki, Yuichi; Stack, T Daniel P; Storr, Tim

    2009-09-07

    The geometric and electronic structures of a series of one-electron oxidized group 10 metal salens (Ni, Pd, Pt) have been investigated in solution and in the solid state. Ni (1) and Pd (2) complexes of the tetradentate salen ligand N,N'-bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediamine (H(2)Salcn) have been examined along with the Pt (3) complex of the salen ligand N,N'-bis(3,5-di-tert-butylsalicylidene)-1,2-ethylenediamine (H(2)Salen). All three oxidized compounds exist as ligand radical species in solution and in the solid state. The solid state structures of [1](+) and [3](+) exhibit a symmetric coordination sphere contraction relative to the neutral forms. By contrast, the coordination sphere of the Pd derivative [2](+) exhibits a pronounced asymmetry in the solid state. In solution, the oxidized derivatives display intense low-energy NIR transitions consistent with their classification as ligand radical compounds. Interestingly, the degree of communication between the phenolate moieties depends strongly on the central metal ion, within the Ni, Pd, and Pt series. Electrochemical measurements and UV-vis-NIR spectroscopy, in conjunction with density functional theory calculations provide insights into the degree of delocalization of the one-electron hole in these systems. The Pd complex [2](+) is the least delocalized and is best described as a borderline Class II/III intervalence complex based on the Robin-Day classification system. The Ni [1](+) and Pt [3](+) analogues are Class III (fully delocalized) intervalence compounds. Delocalization is dependent on the electronic coupling between the redox-active phenolate ligands, mediated by overlap between the formally filled metal d(xz) orbital and the appropriate ligand molecular orbital. The degree of coupling increases in the order Pd < Ni < Pt for the one-electron oxidized group 10 metal salens.

  18. The direct measurement of structural mass, stiffness and damping properties

    NASA Astrophysics Data System (ADS)

    Lee, H. G.; Dobson, B. J.

    1991-02-01

    A method is described for directly evaluating the spatial properties (i.e., mass, stiffness and damping) of a structure from experimentally measured frequency response data. The resulting structural model can be compared directly with an equivalent finite element idealization. The effects of model reduction, such as the Guyan method, which can be employed to ensure that the experimental and theoretical models contain comparable degrees of freedom, are discussed. It is shown that it is possible to detect regions within the structure at which differences exist between the experimental and theoretical models. Further, it is demonstrated that the resulting experimentally derived models can be used to predict the effects of structural modifications upon the frequency response behaviour of the structure.

  19. The study of precision measurement of pelvis spatial structure

    NASA Astrophysics Data System (ADS)

    Ma, Xiang; Ouyang, Jianfei; Qu, Xinghua

    2009-12-01

    Osteometry is fundamental for anthropometry. It provides the key technology and value to the study of palaeoanthropology, medicine, and criminal investigation. The traditional osteometry that has been widely accepted and used since 18th century has no longer met the information demand for modern research and application. It is significant and necessary to create an advanced 3-dimensional osteometry technique for anthropometry. This paper presents a new quick and accurate method to measure human pelvis through mathematical modeling. The pelvis is a complex combination of bones, which consists of three connected parts: hipbones, sacrum, and coccyx. There are over 40 items to be measured for the 1-dimension characteristics. In this paper, a combined measuring technology is developed for pelvis measurement. It uses machine vision systems and a portable measuring arm to obtain key geometry parameters of the pelvis. The mathematics models of the pelvis spatial structure and its parts are created through the process of data collecting, digging, assembling, and modeling. The experiment shows that the proposed technology can meet traditional osteometry and obtain entire 1D geometric parameters of the pelvis, such as maximum breadth and height, diameter of obstetric conjugata, inclination angle, and sakralneigungswinkel, etc. at the same time after modeling. Besides making the measurements above, the proposed technology can measure the geometry characteristics of pelvis and its parts, such as volume, surface area, curvature, and spatial structure, which are almost impossible for traditional technology. The overall measuring error is less than 0.1mm.

  20. The study of precision measurement of pelvis spatial structure

    NASA Astrophysics Data System (ADS)

    Ma, Xiang; Ouyang, Jianfei; Qu, Xinghua

    2010-03-01

    Osteometry is fundamental for anthropometry. It provides the key technology and value to the study of palaeoanthropology, medicine, and criminal investigation. The traditional osteometry that has been widely accepted and used since 18th century has no longer met the information demand for modern research and application. It is significant and necessary to create an advanced 3-dimensional osteometry technique for anthropometry. This paper presents a new quick and accurate method to measure human pelvis through mathematical modeling. The pelvis is a complex combination of bones, which consists of three connected parts: hipbones, sacrum, and coccyx. There are over 40 items to be measured for the 1-dimension characteristics. In this paper, a combined measuring technology is developed for pelvis measurement. It uses machine vision systems and a portable measuring arm to obtain key geometry parameters of the pelvis. The mathematics models of the pelvis spatial structure and its parts are created through the process of data collecting, digging, assembling, and modeling. The experiment shows that the proposed technology can meet traditional osteometry and obtain entire 1D geometric parameters of the pelvis, such as maximum breadth and height, diameter of obstetric conjugata, inclination angle, and sakralneigungswinkel, etc. at the same time after modeling. Besides making the measurements above, the proposed technology can measure the geometry characteristics of pelvis and its parts, such as volume, surface area, curvature, and spatial structure, which are almost impossible for traditional technology. The overall measuring error is less than 0.1mm.

  1. Structural Modeling of Measurement Error in Generalized Linear Models with Rasch Measures as Covariates

    ERIC Educational Resources Information Center

    Battauz, Michela; Bellio, Ruggero

    2011-01-01

    This paper proposes a structural analysis for generalized linear models when some explanatory variables are measured with error and the measurement error variance is a function of the true variables. The focus is on latent variables investigated on the basis of questionnaires and estimated using item response theory models. Latent variable…

  2. Structural Modeling of Measurement Error in Generalized Linear Models with Rasch Measures as Covariates

    ERIC Educational Resources Information Center

    Battauz, Michela; Bellio, Ruggero

    2011-01-01

    This paper proposes a structural analysis for generalized linear models when some explanatory variables are measured with error and the measurement error variance is a function of the true variables. The focus is on latent variables investigated on the basis of questionnaires and estimated using item response theory models. Latent variable…

  3. Detailed Geological Modelling in Urban Areas focused on Structures relevant to the Near Surface Groundwater Flow in the context of Climatic Changes

    NASA Astrophysics Data System (ADS)

    Bach, T.; Pallesen, T. M.; Jensen, N. P.; Mielby, S.; Sandersen, P.; Kristensen, M.

    2015-12-01

    This case demonstrates a practical example from the city of Odense (DK) where new geological modeling techniques has been developed and used in the software GeoScene3D, to create a detailed voxel model of the anthropogenic layer. The voxel model has been combined with a regional hydrostratigraphic layer model. The case is part of a pilot project partly financed by VTU (Foundation for Development of Technology in the Danish Water Sector) and involves many different datatypes such as borehole information, geophysical data, human related elements (landfill, pipelines, basements, roadbeds etc). In the last few years, there has been increased focus on detailed geological modeling in urban areas. The models serve as important input to hydrological models. This focus is partly due to climate changes as high intensity rainfalls are seen more often than in the past, and water recharge is a topic too. In urban areas, this arises new challenges. There is a need of a high level of detailed geological knowledge for the uppermost zone of the soil, which typically are problematic due to practically limitations, especially when using geological layer models. Furthermore, to accommodate the need of a high detail, all relevant available data has to be used in the modeling process. Human activity has deeply changed the soil layers, e.g. by constructions as roadbeds, buildings with basements, pipelines, landfill etc. These elements can act as barriers or pathways regarding surface near groundwater flow and can attribute to local flooding or mobilization and transport of contaminants etc. A geological voxel model is built by small boxes (a voxel). Each box can contain several parameters, ex. lithology, transmissivity or contaminant concentration. Human related elements can be implemented using tools, which gives the modeler advanced options for making detailed small-scale models. This case demonstrates the workflow and the resulting geological model for the pilot area.

  4. Measuring RNA structure transcriptome-wide with icSHAPE.

    PubMed

    Chan, Dalen; Feng, Chao; Spitale, Robert C

    2017-03-20

    RNA molecules can be found at the heart of nearly every aspect of gene regulation: from gene expression to protein translation. The ability of RNA molecules to fold into intricate structures guides their function. Chemical methods to measure RNA structure have been part of the RNA biologists toolkit for several decades. These methods, although often cumbersome and difficult to perform on large RNAs, are notable for their accuracy and precision of structural measurements. Recent extension of these methods to transcriptome-wide analyses has opened the door to interrogating the structure of complete RNA molecules inside cells. Within this manuscript we describe the biochemical basis for the methodology behind a novel technology, icSHAPE, which measures RNA flexibility and single-strandedness in RNA. Novel methods such as icSHAPE have greatly expanded our understanding of RNA function and have paved the way to expansive analyses of large groups of RNA structures as they function inside the native environment of the cell.

  5. A Structured-Grid Quality Measure for Simulated Hypersonic Flows

    NASA Technical Reports Server (NTRS)

    Alter, Stephen J.

    2004-01-01

    A structured-grid quality measure is proposed, combining three traditional measurements: intersection angles, stretching, and curvature. Quality assesses whether the grid generated provides the best possible tradeoffs in grid stretching and skewness that enable accurate flow predictions, whereas the grid density is assumed to be a constraint imposed by the available computational resources and the desired resolution of the flow field. The usefulness of this quality measure is assessed by comparing heat transfer predictions from grid convergence studies for grids of varying quality in the range of [0.6-0.8] on an 8'half-angle sphere-cone, at laminar, perfect gas, Mach 10 wind tunnel conditions.

  6. Uncertainty Quantification for Monitoring of Civil Structures from Vibration Measurements

    NASA Astrophysics Data System (ADS)

    Döhler, Michael; Mevel, Laurent

    2014-05-01

    Health Monitoring of civil structures can be performed by detecting changes in the modal parameters of a structure, or more directly in the measured vibration signals. For a continuous monitoring the excitation of a structure is usually ambient, thus unknown and assumed to be noise. Hence, all estimates from the vibration measurements are realizations of random variables with inherent uncertainty due to (unknown) process and measurement noise and finite data length. In this talk, a strategy for quantifying the uncertainties of modal parameter estimates from a subspace-based system identification approach is presented and the importance of uncertainty quantification in monitoring approaches is shown. Furthermore, a damage detection method is presented, which is based on the direct comparison of the measured vibration signals without estimating modal parameters, while taking the statistical uncertainty in the signals correctly into account. The usefulness of both strategies is illustrated on data from a progressive damage action on a prestressed concrete bridge. References E. Carden and P. Fanning. Vibration based condition monitoring: a review. Structural Health Monitoring, 3(4):355-377, 2004. M. Döhler and L. Mevel. Efficient multi-order uncertainty computation for stochastic subspace identification. Mechanical Systems and Signal Processing, 38(2):346-366, 2013. M. Döhler, L. Mevel, and F. Hille. Subspace-based damage detection under changes in the ambient excitation statistics. Mechanical Systems and Signal Processing, 45(1):207-224, 2014.

  7. The prediction and measurement of sound radiated by structures

    NASA Technical Reports Server (NTRS)

    Lyon, R. H.; Brito, J. D.

    1976-01-01

    Theories regarding the radiation of sound are reviewed and the implementation in strategies for explaining or measuring the sound produced by practical strucutres are discussed. Particular attention is given to those aspects that relate to the determination of the relative amounts of sound generated by various parts of a machine or structure, which can be very useful information for noise reduction efforts.

  8. Skin phantoms with realistic vessel structure for OCT measurements

    NASA Astrophysics Data System (ADS)

    Bykov, A. V.; Popov, A. P.; Kinnunen, M.; Prykäri, T.; Priezzhev, A. V.; Myllylä, R.

    2010-11-01

    We present here a novel phantom for optical coherence tomography (OCT) made of polyvinyl chloride-plastisol (PVCP). The optical properties of PVCP were estimated by the Mie theory and deduced from OCT measurements. Titanium dioxide (TiO2) powder and black plastic colour (light-absorbing plastic ink) were used to introduce scattering to the phantom and create capillary structure, respectively.

  9. Factor Structure and Validation of a Set of Readiness Measures.

    ERIC Educational Resources Information Center

    Kaufman, Maurice; Lynch, Mervin

    A study was undertaken to identify the factor structure of a battery of readiness measures and to demonstrate the concurrent and predictive validity of one instrument in that battery--the Pre-Reading Screening Procedures (PSP). Concurrent validity was determined by examining the correlation of the PSP with the Metropolitan Readiness Test (MRT),…

  10. The Effect of Quantum-Mechanical Interference on Precise Measurements of the n = 2 Triplet P Fine Structure of Helium

    SciTech Connect

    Marsman, A.; Horbatsch, M.; Hessels, E. A.

    2015-09-15

    For many decades, improvements in both theory and experiment of the fine structure of the n = 2 triplet P levels of helium have allowed for an increasingly precise determination of the fine-structure constant. Recently, it has been observed that quantum-mechanical interference between neighboring resonances can cause significant shifts, even if such neighboring resonances are separated by thousands of natural widths. The shifts depend in detail on the experimental method used for the measurement, as well as the specific experimental parameters employed. Here, we review how these shifts apply for the most precise measurements of the helium 2{sup 3}P fine-structure intervals.

  11. The influence of construction measurement and structure storey on seismic performance of masonry structure

    NASA Astrophysics Data System (ADS)

    Sun, Baitao; Zhao, Hexian; Yan, Peilei

    2017-08-01

    The damage of masonry structures in earthquakes is generally more severe than other structures. Through the analysis of two typical earthquake damage buildings in the Wenchuan earthquake in Xuankou middle school, we found that the number of storeys and the construction measures had great influence on the seismic performance of masonry structures. This paper takes a teachers’ dormitory in Xuankou middle school as an example, selected the structure arrangement and storey number as two independent variables to design working conditions. Finally we researched on the seismic performance difference of masonry structure under two variables by finite element analysis method.

  12. A rail wear measurement method based on structured light scanning

    NASA Astrophysics Data System (ADS)

    Chen, Peng; Wang, Peijun; Lauer, Martin; Tang, Xiaomin; Wang, Jindong

    2017-02-01

    Rail wear measurement is a necessary task in railway infrastructure inspection. To acquire the wear amounts accurately with more continuous scanning data, a rail wear measurement method based on structured light scanning is proposed in this paper. The CAD model of the rail is converted into a point set, and the data registration is implemented by aligning the scanning data to the point cloud generated by the CAD model. On a cross section plane of the rail, the vertical and lateral wear amounts are calculated by the nearby points projected onto the plane. To verify the accuracy of wear measurement based on structured light scanning, the wear amounts calculated by laser scanning data are compared. For the comparison, an experiment is designed to ensure that the same plane is sliced in two different kinds of measurement. On the cross section plane, the wear amounts are calculated by the distances from these points to the 2D profile of the rail CAD model, and then the results are compared with those from laser scanning data for the accuracy evaluation. It indicates that the accuracy of the structured light scanning is sufficient for railway track wear measurement.

  13. Lidar Measurements of the Thermic Structure in the Troposphere

    NASA Technical Reports Server (NTRS)

    Werner, Ch.

    1973-01-01

    Lidar measurements by UTHE (1972) and similar measurements with acoustic radar by HALL (1972) have shown, that short time variations in the troposphere can be determined. Aerosol backscatter measurements give the vertical structure. A series of such results shows the time variation of the tropospheric structure. The Figure is an example for a measuring period during half an hour in summer 1972 (1 pulse per minute). These variations were produced by humidity variations. For example, at humidity variations from 75% to 77% aerosol particles with 1 micron radius change their radii during 50 to 100 milliseconds. By lidar technique it is possible to determine this effect qualitatively. With a pulse repetition rate of 1 per second we plan to investigate the thermic structure at different weather conditions. By simultaneous measurements of the nitrogen Raman component it would be possible to compare the short time variations by temperature and humidity. The influence of wind can be determined by scanning a defined region (region or space). The meteorologist is interested in results of short time variations in the troposphere (microscale). By this remote sensing method he can get these values continuously.

  14. Structural Measurements from Images of Noble Gas Diffusion

    NASA Astrophysics Data System (ADS)

    Cadman, Robert V.; Kadlecek, Stephen J.; Emami, Kiarash; MacDuffie Woodburn, John; Vahdat, Vahid; Ishii, Masaru; Rizi, Rahim R.

    2009-03-01

    Magnetic resonance imaging of externally polarized noble gases such as ^3He has been used for pulmonary imaging for more than a decade. Because gas diffusion is impeded by the alveoli, the diffusion coefficient of gas in the lung, measured on a time scale of milliseconds, is reduced compared to that of the same gas mixture in the absence of restrictions. When the alveolar walls decay, as in emphysema, diffusivity in the lung increases. In this paper, the relationship between diffusion measurements and the size of the restricting structures will be discussed. The simple case of diffusion in an impermeable cylinder, a structure similar to the upper respiratory airways in mammals, has been studied. A procedure will be presented by which airways of order 2 mm in diameter may be accurately measured; demonstration experiments with plastic tubes will also be presented. The additional developments needed before this technique becomes practical will be briefly discussed.

  15. Measurement of the proton structure function F 2 from the 1993 HERA data

    NASA Astrophysics Data System (ADS)

    Derrick, M.; Krakauer, D.; Magill, S.; Musgrave, B.; Repond, J.; Schlereth, J.; Stanek, R.; Talaga, R. L.; Thron, J.; Arzarello, F.; Ayad, R.; Bari, G.; Basile, M.; Bellagamba, L.; Boscherini, D.; Bruni, A.; Bruni, G.; Bruni, P.; Cara Romeo, G.; Castellini, G.; Chiarini, M.; Cifarelli, L.; Cindolo, F.; Ciralli, F.; Contin, A.; D'Auria, S.; Frasconi, F.; Giusti, P.; Iacobucci, G.; Laurenti, G.; Levi, G.; Margotti, A.; Massam, T.; Nania, R.; Nemoz, C.; Palmonari, F.; Polini, A.; Sartorelli, G.; Timellini, R.; Zamora Garcia, Y.; Zichichi, A.; Bargende, A.; Crittenden, J.; Desch, K.; Diekmann, B.; Doeker, T.; Feld, L.; Frey, A.; Geerts, M.; Geitz, G.; Grothe, M.; Hartmann, H.; Haun, D.; Heinloth, K.; Hilger, E.; Jakob, H.-P.; Katz, U. F.; Mari, S. M.; Mass, A.; Mengel, S.; Mollen, J.; Paul, E.; Rembser, Ch.; Schattevoy, R.; Schneider, J.-L.; Schramm, D.; Stamm, J.; Wedemeyer, R.; Campbell-Robson, S.; Cassidy, A.; Dyce, N.; Foster, B.; George, S.; Gilmore, R.; Heath, G. P.; Heath, H. F.; Llewellyn, T. J.; Morgado, C. J. S.; Norman, D. J. P.; O'Mara, J. A.; Tapper, R. J.; Wilson, S. S.; Yoshida, R.; Rau, R. R.; Arneodo, M.; Iannotti, L.; Schioppa, M.; Susinno, G.; Bernstein, A.; Caldwell, A.; Gialas, I.; Parsons, J. A.; Ritz, S.; Sciulli, F.; Straub, P. B.; Wai, L.; Yang, S.; Borzemski, P.; Chwastowski, J.; Eskreys, A.; Piotrzkowski, K.; Zachara, M.; Zawiejski, L.; Adamczyk, L.; Bednarek, B.; Eskreys, K.; Jeleń, K.; Kisielewska, D.; Kowalski, T.; Rulikowska-Zarębska, E.; Suszycki, L.; Zając, J.; Kędzierski, T.; Kotański, A.; Przybycień, M.; Bauerdick, L. A. T.; Behrens, U.; Bienlein, J. K.; Böttcher, S.; Coldewey, C.; Drews, G.; Flasiński, M.; Gilkinson, D. J.; Göttlicher, P.; Gutjahr, B.; Haas, T.; Hagge, L.; Hain, W.; Hasell, D.; Heßling, H.; Hultschig, H.; Iga, Y.; Joos, P.; Kasemann, M.; Klanner, R.; Koch, W.; Köpke, L.; Kötz, U.; Kowalski, H.; Kröger, W.; Krüger, J.; Labs, J.; Ladage, A.; Löhr, B.; Löwe, M.; Lüke, D.; Mainusch, J.; Mańczak, O.; Ng, J. S. T.; Nickel, S.; Notz, D.; Ohrenberg, K.; Roco, M.; Rohde, M.; Roldán, J.; Schneekloth, U.; Schulz, W.; Selonke, F.; Stiliaris, E.; Voß, T.; Westphal, D.; Wolf, G.; Youngman, C.; Grabosch, H. J.; Leich, A.; Meyer, A.; Rethfeldt, C.; Schlenstedt, S.; Barbagli, G.; Pelfer, P.; Anzivino, G.; Maccarrone, G.; de Pasquale, S.; Qian, S.; Votano, L.; Bamberger, A.; Freidhof, A.; Poser, T.; Söldner-Rembold, S.; Schroeder, J.; Theisen, G.; Trefzger, T.; Brook, N. H.; Bussey, P. J.; Doyle, A. T.; Fleck, I.; Jamieson, V. A.; Saxon, D. H.; Utley, M. L.; Wilson, A. S.; Dannemann, A.; Holm, U.; Horstmann, D.; Kammerlocher, H.; Krebs, B.; Neumann, T.; Sinkus, R.; Wick, K.; Badura, E.; Burow, B. D.; Fürtjes, A.; Lohrmann, E.; Milewski, J.; Nakahata, M.; Pavel, N.; Poelz, G.; Schott, W.; Terron, J.; Zetsche, F.; Bacon, T. C.; Beuselinck, R.; Butterworth, I.; Gallo, E.; Harris, V. L.; Hung, B. H.; Long, K. R.; Miller, D. B.; Morawitz, P. P. O.; Prinias, A.; Sedgbeer, J. K.; Whitfield, A. F.; Mallik, U.; McCliment, E.; Wang, M. Z.; Zhang, Y.; Cloth, P.; Filges, D.; An, S. H.; Hong, S. M.; Nam, S. W.; Park, S. K.; Suh, M. H.; Yon, S. H.; Imlay, R.; Kartik, S.; Kim, H.-J.; McNeil, R. R.; Metcalf, W.; Nadendla, V. K.; Barreiro, F.; Cases, G.; Graciani, R.; Hernández, J. M.; Hervás, L.; Labarga, L.; Del Peso, J.; Puga, J.; de Trocóniz, J. F.; Ikraiam, F.; Mayer, J. K.; Smith, G. R.; Corriveau, F.; Hanna, D. S.; Hartmann, J.; Hung, L. W.; Lim, J. N.; Matthews, C. G.; Mitchell, J. W.; Patel, P. M.; Sinclair, L. E.; Stairs, D. G.; St. Laurent, M.; Ullmann, R.; Bashkirov, V.; Dolgoshein, B. A.; Stifutkin, A.; Bashindzhagyan, G. L.; Ermolov, P. F.; Gladilin, L. K.; Golubkov, Y. A.; Kobrin, V. D.; Kuzmin, V. A.; Proskuryakov, A. S.; Savin, A. A.; Shcheglova, L. M.; Solomin, A. N.; Zotov, N. P.; Bentvelsen, S.; Botje, M.; Chlebana, F.; Dake, A.; Engelen, J.; de Jong, P.; de Kamps, M.; Kooijman, P.; Kruse, A.; O'Dell, V.; Tenner, A.; Tiecke, H.; Verkerke, W.; Vreeswijk, M.; Wiggers, L.; de Wolf, E.; van Woudenberg, R.; Acosta, D.; Bylsma, B.; Durkin, L. S.; Honscheid, K.; Li, C.; Ling, T. Y.; McLean, K. W.; Murray, W. N.; Park, I. H.; Romanowski, T. A.; Seidlein, R.; Bailey, D. S.; Blair, G. A.; Byrne, A.; Cashmore, R. J.; Cooper-Sarkar, A. M.; Daniels, D.; Devenish, R. C. E.; Harnew, N.; Lancaster, M.; Luffman, P. E.; Lindemann, L.; McFall, J.; Nath, C.; Quadt, A.; Uijterwaal, H.; Walczak, R.; Wilson, F. F.; Yip, T.; Abbiendi, G.; Bertolin, A.; Brugnera, R.; Carlin, R.; Dal Corso, F.; de Giorgi, M.; Dosselli, U.; Gasparini, F.; Limentani, S.; Morandin, M.; Posocco, M.; Stanco, L.; Stroili, R.; Voci, C.; Bulmahn, J.; Butterworth, J. M.; Feild, R. G.; Oh, B. Y.; Whitmore, J. J.; D'Agostini, G.; Iori, M.; Marini, G.; Mattioli, M.; Nigro, A.; Tassi, E.; Hart, J. C.; McCubbin, N. A.; Prytz, K.; Shah, T. P.; Short, T. L.; Barberis, E.; Cartiglia, N.; Dubbs, T.; Heusch, C.; van Hook, M.; Hubbard, B.; Lockman, W.; Rahn, J. T.; Sadrozinski, H. F.-W.; Seiden, A.; Biltzinger, J.; Seifert, R. J.; Walenta, A. H.; Zech, G.; Abramowicz, H.; Briskin, G.; Dagan, S.; Levy, A.; Hasegawa, T.; Hazumi, M.; Ishii, T.; Kuze, M.; Mine, S.; Nagasawa, Y.; Nagira, T.; Nakao, M.; Suzuki, I.; Tokushuku, K.; Yamada, S.; Yamazaki, Y.; Chiba, M.; Hamatsu, R.; Hirose, T.; Homma, K.; Kitamura, S.; Nagayama, S.; Nakamitsu, Y.; Cirio, R.; Costa, M.; Ferrero, M. I.; Lamberti, L.; Maselli, S.; Peroni, C.; Sacchi, R.; Solano, A.; Staiano, A.; Dardo, M.; Bandyopadhyay, D.; Benard, F.; Brkic, M.; Crombie, M. B.; Gingrich, D. M.; Hartner, G. F.; Joo, K. K.; Levman, G. M.; Martin, J. F.; Orr, R. S.; Sampson, C. R.; Teuscher, R. J.; Catterall, C. D.; Jones, T. W.; Kaziewicz, P. B.; Lane, J. B.; Saunders, R. L.; Shulman, J.; Blankenship, K.; Kochocki, J.; Lu, B.; Mo, L. W.; Bogusz, W.; Charchula, K.; Ciborowski, J.; Gajewski, J.; Grzelak, G.; Kasprzak, M.; Krzyżanowski, M.; Muchorowski, K.; Nowak, R. J.; Pawlak, J. M.; Tymieniecka, T.; Wróblewski, A. K.; Zakrzewski, J. A.; Żarnecki, A. F.; Adamus, M.; Eisenberg, Y.; Glasman, C.; Karshon, U.; Revel, D.; Shapira, A.; Ali, I.; Behrens, B.; Dasu, S.; Fordham, C.; Foudas, C.; Goussiou, A.; Loveless, R. J.; Reeder, D. D.; Silverstein, S.; Smith, W. H.; Tsurugai, T.; Bhadra, S.; Frisken, W. R.; Furutani, K. M.

    1995-09-01

    The ZEUS detector has been used to measure the proton structure function F 2. During 1993 HERA collided 26.7 GeV electrons on 820 GeV protons. The data sample corresponds to an integrated luminosity of 0.54 pb-1, representing a twenty fold increase in statistics compared to that of 1992. Results are presented for 7< Q 2<104 GeV2 and x values as low as 3×10-4. The rapid rise in F 2 as x decreases observed previously is now studied in greater detail and persists for Q 2 values up to 500 GeV2.

  16. Statistical measures on residue-level protein structural properties.

    PubMed

    Huang, Yuanyuan; Bonett, Stephen; Kloczkowski, Andrzej; Jernigan, Robert; Wu, Zhijun

    2011-07-01

    The atomic-level structural properties of proteins, such as bond lengths, bond angles, and torsion angles, have been well studied and understood based on either chemistry knowledge or statistical analysis. Similar properties on the residue-level, such as the distances between two residues and the angles formed by short sequences of residues, can be equally important for structural analysis and modeling, but these have not been examined and documented on a similar scale. While these properties are difficult to measure experimentally, they can be statistically estimated in meaningful ways based on their distributions in known proteins structures. Residue-level structural properties including various types of residue distances and angles are estimated statistically. A software package is built to provide direct access to the statistical data for the properties including some important correlations not previously investigated. The distributions of residue distances and angles may vary with varying sequences, but in most cases, are concentrated in some high probability ranges, corresponding to their frequent occurrences in either α-helices or β-sheets. Strong correlations among neighboring residue angles, similar to those between neighboring torsion angles at the atomic-level, are revealed based on their statistical measures. Residue-level statistical potentials can be defined using the statistical distributions and correlations of the residue distances and angles. Ramachandran-like plots for strongly correlated residue angles are plotted and analyzed. Their applications to structural evaluation and refinement are demonstrated. With the increase in both number and quality of known protein structures, many structural properties can be derived from sets of protein structures by statistical analysis and data mining, and these can even be used as a supplement to the experimental data for structure determinations. Indeed, the statistical measures on various types of

  17. Topography measurement of micro structure by modulation-based method

    NASA Astrophysics Data System (ADS)

    Zhou, Yi; Tang, Yan; Liu, Junbo; Deng, Qinyuan; Cheng, Yiguang; Hu, Song

    2016-10-01

    Dimensional metrology for micro structure plays an important role in addressing quality issues and observing the performance of micro-fabricated products. Different from the traditional white-light interferometry approach, the modulation-based method is expected to measure topography of micro structure by the obtained modulation of each interferometry image. Through seeking the maximum modulation of every pixel respectively in Z direction, the method could obtain the corresponding height of individual pixel and finally get topography of the structure. Owing to the characteristic of modulation, the proposed method which is not influenced by the change of background light intensity caused by instable light source and different reflection index of the structure could be widely applied with high stability. The paper both illustrates the principle of this novel method and conducts the experiment to verify the feasibility.

  18. Advanced optical measuring systems for measuring the properties of fluids and structures

    NASA Technical Reports Server (NTRS)

    Decker, A. J.

    1986-01-01

    Four advanced optical models are reviewed for the measurement of visualization of flow and structural properties. Double-exposure, diffuse-illumination, holographic interferometry can be used for three-dimensional flow visualization. When this method is combined with optical heterodyning, precise measurements of structural displacements or fluid density are possible. Time-average holography is well known as a method for displaying vibrational mode shapes, but it also can be used for flow visualization and flow measurements. Deflectometry is used to measure or visualize the deflection of light rays from collimation. Said deflection occurs because of refraction in a fluid or because of reflection from a tilted surface. The moire technique for deflectometry, when combined with optical heterodyning, permits very precise measurements of these quantities. The rainbow schlieren method of deflectometry allows varying deflection angles to be encoded with colors for visualization.

  19. NOSS Altimeter Detailed Algorithm specifications

    NASA Technical Reports Server (NTRS)

    Hancock, D. W.; Mcmillan, J. D.

    1982-01-01

    The details of the algorithms and data sets required for satellite radar altimeter data processing are documented in a form suitable for (1) development of the benchmark software and (2) coding the operational software. The algorithms reported in detail are those established for altimeter processing. The algorithms which required some additional development before documenting for production were only scoped. The algorithms are divided into two levels of processing. The first level converts the data to engineering units and applies corrections for instrument variations. The second level provides geophysical measurements derived from altimeter parameters for oceanographic users.

  20. Measuring the robustness of network community structure using assortativity.

    PubMed

    Shizuka, Daizaburo; Farine, Damien R

    2016-02-01

    The existence of discrete social clusters, or 'communities', is a common feature of social networks in human and nonhuman animals. The level of such community structure in networks is typically measured using an index of modularity, Q. While modularity quantifies the degree to which individuals associate within versus between social communities and provides a useful measure of structure in the social network, it assumes that the network has been well sampled. However, animal social network data is typically subject to sampling errors. In particular, the associations among individuals are often not sampled equally, and animal social network studies are often based on a relatively small set of observations. Here, we extend an existing framework for bootstrapping network metrics to provide a method for assessing the robustness of community assignment in social networks using a metric we call community assortativity (rcom). We use simulations to demonstrate that modularity can reliably detect the transition from random to structured associations in networks that differ in size and number of communities, while community assortativity accurately measures the level of confidence based on the detectability of associations. We then demonstrate the use of these metrics using three publicly available data sets of avian social networks. We suggest that by explicitly addressing the known limitations in sampling animal social network, this approach will facilitate more rigorous analyses of population-level structural patterns across social systems.