Sample records for detection final technical

  1. Final Technical Report: PV Fault Detection Tool.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    King, Bruce Hardison; Jones, Christian Birk

    The PV Fault Detection Tool project plans to demonstrate that the FDT can (a) detect catastrophic and degradation faults and (b) identify the type of fault. This will be accomplished by collecting fault signatures using different instruments and integrating this information to establish a logical controller for detecting, diagnosing and classifying each fault.

  2. An Advanced Platform for Biomolecular Detection and Analysis Systems

    DTIC Science & Technology

    2005-02-01

    AFRL-IF-RS-TR-2005-54 Final Technical Report February 2005 AN ADVANCED PLATFORM FOR BIOMOLECULAR DETECTION AND ANALYSIS SYSTEMS...SUBTITLE AN ADVANCED PLATFORM FOR BIOMOLECULAR DETECTION AND ANALYSIS SYSTEMS 6. AUTHOR(S) David J. Beebe 5. FUNDING NUMBERS G...detection, analysis and response as well as many non BC warfare applications such as environmental toxicology, clinical detection and diagnosis

  3. Troubleshooting Instruction in Vocational-Technical Education Via Dynamic Simulation. Final Report.

    ERIC Educational Resources Information Center

    Finch, Curtis R.

    This study was designed to examine the feasibility of using simulation as a means of teaching vocational-technical students to detect and identify malfunctions in selected electrical and mechanical systems. A dynamic simulator was employed which features interchangeable panels and logic that permits the simulation of electrical or mechanical…

  4. Off-road axle detection sensor (ORADS) : occlusion feasibility study, final technical report, 27 August, 1997.

    DOT National Transportation Integrated Search

    1997-08-27

    The work accomplished under this initiative is in direct relation to the development effort proposed by Spectra : Research, Inc. (S*R) for an "Off-Road Axle Detection Sensor (ORADS)". The feasibility study was performed to : investigate potential occ...

  5. Sniper detection using infrared camera: technical possibilities and limitations

    NASA Astrophysics Data System (ADS)

    Kastek, M.; Dulski, R.; Trzaskawka, P.; Bieszczad, G.

    2010-04-01

    The paper discusses technical possibilities to build an effective system for sniper detection using infrared cameras. Descriptions of phenomena which make it possible to detect sniper activities in infrared spectra as well as analysis of physical limitations were performed. Cooled and uncooled detectors were considered. Three phases of sniper activities were taken into consideration: before, during and after the shot. On the basis of experimental data the parameters defining the target were determined which are essential in assessing the capability of infrared camera to detect sniper activity. A sniper body and muzzle flash were analyzed as targets. The simulation of detection ranges was done for the assumed scenario of sniper detection task. The infrared sniper detection system was discussed, capable of fulfilling the requirements. The discussion of the results of analysis and simulations was finally presented.

  6. PV Systems Reliability Final Technical Report: Ground Fault Detection

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lavrova, Olga; Flicker, Jack David; Johnson, Jay

    We have examined ground faults in PhotoVoltaic (PV) arrays and the efficacy of fuse, current detection (RCD), current sense monitoring/relays (CSM), isolation/insulation (Riso) monitoring, and Ground Fault Detection and Isolation (GFID) using simulations based on a Simulation Program with Integrated Circuit Emphasis SPICE ground fault circuit model, experimental ground faults installed on real arrays, and theoretical equations.

  7. Financial technical indicator based on chaotic bagging predictors for adaptive stock selection in Japanese and American markets

    NASA Astrophysics Data System (ADS)

    Suzuki, Tomoya; Ohkura, Yuushi

    2016-01-01

    In order to examine the predictability and profitability of financial markets, we introduce three ideas to improve the traditional technical analysis to detect investment timings more quickly. Firstly, a nonlinear prediction model is considered as an effective way to enhance this detection power by learning complex behavioral patterns hidden in financial markets. Secondly, the bagging algorithm can be applied to quantify the confidence in predictions and compose new technical indicators. Thirdly, we also introduce how to select more profitable stocks to improve investment performance by the two-step selection: the first step selects more predictable stocks during the learning period, and then the second step adaptively and dynamically selects the most confident stock showing the most significant technical signal in each investment. Finally, some investment simulations based on real financial data show that these ideas are successful in overcoming complex financial markets.

  8. Innovative Methodology For Detection of Fracture-Controlled Sweet Spots in the Northern Appalachian Basin

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Jacobi, Rober

    2007-03-28

    This Topical Report (#6 of 9) consists of the figures 3.6-13 to (and including) 3.6-18 (and appropriate figure captions) that accompany the Final Technical Progress Report entitled: “Innovative Methodology for Detection of Fracture-Controlled Sweet Spots in the Northern Appalachian Basin” for DOE/NETL Award DE-AC26-00NT40698.

  9. A Novel Passive Millimeter Imager for Broad-Area Search - Final Report on Project PL09-NPMI-PD07 (PNNL-55180)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Tedeschi, Jonathan R.; Bernacki, Bruce E.; Kelly, James F.

    2011-12-31

    This report describes research and development efforts toward a novel passive millimeter-wave (mm-wave) electromagnetic imaging device for broad-area search. It addresses the technical challenge of detecting anomalies that occupy a small fraction of a pixel. The purpose of the imager is to pinpoint suspicious locations for cuing subsequent higher-resolution imaging. The technical basis for the approach is to exploit thermal and polarization anomalies that distinguish man-made features from natural features.

  10. Final technical report for ITS for voluntary emission reduction : an ITS operational test using real-time vehicle emissions detection

    DOT National Transportation Integrated Search

    1998-05-01

    The Smart Sign project has successfully demonstrated the merging of two separate technological disciplines of highway messaging and on-road vehicle emissions sensing into an advanced ITS public information system. This operational test has demonstrat...

  11. UAS Integration in the NAS Project: Part Task 6 V & V Simulation: Primary Results

    NASA Technical Reports Server (NTRS)

    Rorie, Conrad; Fern, Lisa; Shively, Jay; Santiago, Confesor

    2016-01-01

    This is a presentation of the preliminary results on final V and V (Verification and Validation) activity of [RTCA (Radio Technical Commission for Aeronautics)] SC (Special Committee)-228 DAA (Detect and Avoid) HMI (Human-Machine Interface) requirements for display alerting and guidance.

  12. Electro-optical system for gunshot detection: analysis, concept, and performance

    NASA Astrophysics Data System (ADS)

    Kastek, M.; Dulski, R.; Madura, H.; Trzaskawka, P.; Bieszczad, G.; Sosnowski, T.

    2011-08-01

    The paper discusses technical possibilities to build an effective electro-optical sensor unit for sniper detection using infrared cameras. This unit, comprising of thermal and daylight cameras, can operate as a standalone device but its primary application is a multi-sensor sniper and shot detection system. At first, the analysis was presented of three distinguished phases of sniper activity: before, during and after the shot. On the basis of experimental data the parameters defining the relevant sniper signatures were determined which are essential in assessing the capability of infrared camera to detect sniper activity. A sniper body and muzzle flash were analyzed as targets and the descriptions of phenomena which make it possible to detect sniper activities in infrared spectra as well as analysis of physical limitations were performed. The analyzed infrared systems were simulated using NVTherm software. The calculations for several cameras, equipped with different lenses and detector types were performed. The simulation of detection ranges was performed for the selected scenarios of sniper detection tasks. After the analysis of simulation results, the technical specifications of infrared sniper detection system were discussed, required to provide assumed detection range. Finally the infrared camera setup was proposed which can detected sniper from 1000 meters range.

  13. Detection Of Malware Collusion With Static Dependence Analysis On Inter-App Communication

    DTIC Science & Technology

    2016-12-08

    DETECTION OF MALWARE COLLUSION WITH STATIC DEPENDENCE ANALYSIS ON INTER-APP COMMUNICATION VIRGINIA TECH DECEMBER 2016 FINAL TECHNICAL REPORT... DEPENDENCE ANALYSIS ON INTER-APP COMMUNICATION 5a. CONTRACT NUMBER FA8750-15-2-0076 5b. GRANT NUMBER N/A 5c. PROGRAM ELEMENT NUMBER 61101E 6. AUTHOR(S...exploited. 15. SUBJECT TERMS Malware Collusion; Inter-App Communication; Static Dependence Analysis 16. SECURITY CLASSIFICATION OF: 17. LIMITATION OF

  14. Drugs Off Campus. Final Technical Report. Appendixes.

    ERIC Educational Resources Information Center

    Austin Independent School District, TX. Office of Research and Evaluation.

    In the 1981-82 school year, the Austin Independent School District used trained dogs and handlers to detect illegal drugs and alcohol on the campuses of two high schools. The appendixes of the evaluation designed to gather useful data concerning program effectiveness are presented here. Data from a survey of staff and students, interviews with…

  15. Final Assessment of Manual Ultrasonic Examinations Applied to Detect Flaws in Primary System Dissimilar Metal Welds at North Anna Power Station

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Anderson, Michael T.; Diaz, Aaron A.; Cinson, Anthony D.

    2014-03-24

    PNNL conducted a technical assessment of the NDE issues and protocols that led to missed detections of several axially oriented flaws in a steam generator primary inlet dissimilar metal weld at North Anna Power Station, Unit 1 (NAPS-1). This particular component design exhibits a significant outside-diameter (OD) taper that is not included as a blind performance demonstration mock-up within the industry’s Performance Demonstration Initiative, administered by EPRI. For this reason, the licensee engaged EPRI to assist in the development of a technical justification to support the basis for a site-specific qualification. The service-induced flaws at NAPS-1 were eventually detected asmore » a result of OD surface machining in preparation for a full structural weld overlay. The machining operation uncovered the existence of two through-wall flaws, based on the observance of primary water leaking from the dissimilar metal weld. A total of five axially oriented flaws were detected in varied locations around the weld circumference. The field volumetric examination that was conducted at NAPS-1 was a non-encoded, real-time manual ultrasonic examination. PNNL conducted both an initial assessment, and subsequently, a more rigorous technical evaluation (reported here), which has identified an array of NDE issues that may have led to the subject missed detections. These evaluations were performed through technical reviews and discussions with NRC staff, EPRI NDE Center personnel, industry and ISI vendor personnel, and ultrasonic transducer manufacturers, and laboratory tests, to better understand the underlying issues at North Anna.« less

  16. Reproducibility and quantitation of amplicon sequencing-based detection

    PubMed Central

    Zhou, Jizhong; Wu, Liyou; Deng, Ye; Zhi, Xiaoyang; Jiang, Yi-Huei; Tu, Qichao; Xie, Jianping; Van Nostrand, Joy D; He, Zhili; Yang, Yunfeng

    2011-01-01

    To determine the reproducibility and quantitation of the amplicon sequencing-based detection approach for analyzing microbial community structure, a total of 24 microbial communities from a long-term global change experimental site were examined. Genomic DNA obtained from each community was used to amplify 16S rRNA genes with two or three barcode tags as technical replicates in the presence of a small quantity (0.1% wt/wt) of genomic DNA from Shewanella oneidensis MR-1 as the control. The technical reproducibility of the amplicon sequencing-based detection approach is quite low, with an average operational taxonomic unit (OTU) overlap of 17.2%±2.3% between two technical replicates, and 8.2%±2.3% among three technical replicates, which is most likely due to problems associated with random sampling processes. Such variations in technical replicates could have substantial effects on estimating β-diversity but less on α-diversity. A high variation was also observed in the control across different samples (for example, 66.7-fold for the forward primer), suggesting that the amplicon sequencing-based detection approach could not be quantitative. In addition, various strategies were examined to improve the comparability of amplicon sequencing data, such as increasing biological replicates, and removing singleton sequences and less-representative OTUs across biological replicates. Finally, as expected, various statistical analyses with preprocessed experimental data revealed clear differences in the composition and structure of microbial communities between warming and non-warming, or between clipping and non-clipping. Taken together, these results suggest that amplicon sequencing-based detection is useful in analyzing microbial community structure even though it is not reproducible and quantitative. However, great caution should be taken in experimental design and data interpretation when the amplicon sequencing-based detection approach is used for quantitative analysis of the β-diversity of microbial communities. PMID:21346791

  17. Final report for LDRD project 11-0029 : high-interest event detection in large-scale multi-modal data sets : proof of concept.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Rohrer, Brandon Robinson

    2011-09-01

    Events of interest to data analysts are sometimes difficult to characterize in detail. Rather, they consist of anomalies, events that are unpredicted, unusual, or otherwise incongruent. The purpose of this LDRD was to test the hypothesis that a biologically-inspired anomaly detection algorithm could be used to detect contextual, multi-modal anomalies. There currently is no other solution to this problem, but the existence of a solution would have a great national security impact. The technical focus of this research was the application of a brain-emulating cognition and control architecture (BECCA) to the problem of anomaly detection. One aspect of BECCA inmore » particular was discovered to be critical to improved anomaly detection capabilities: it's feature creator. During the course of this project the feature creator was developed and tested against multiple data types. Development direction was drawn from psychological and neurophysiological measurements. Major technical achievements include the creation of hierarchical feature sets created from both audio and imagery data.« less

  18. Use of Holographic Fringe Linearization Interferometry (FLI) for Detection of Defects.

    DTIC Science & Technology

    1985-11-01

    ei FINAL REPORT on Contract F49620-82-C-0001 USE OF HOLOGRAPHIC FRINGE LINEARIZATION INTERFEROMETRY (FLI) FOR DETECTION OF DEFECTS...TECHNICAL RESULTS OF RESEARCH EFFORT ADDITIONAL TO THOSE IN APPENDIXES A THROUGH EI , •5.1 FINITE ELEMENT ANALYSIS OF FLI EXPERIMENTS Throughout this...between exposures in holographic F1.1 appear to and f(x’,t) = ei k,1(x") in Eq. (4). The revised image of Eq. (5) be localized in the space on and about

  19. Micro-satellite for space debris observation by optical sensors

    NASA Astrophysics Data System (ADS)

    Thillot, Marc; Brenière, Xavier; Midavaine, Thierry

    2017-11-01

    The purpose of this theoretical study carried out under CNES contract is to analyze the feasibility of small space debris detection and classification with an optical sensor on-board micro-satellite. Technical solutions based on active and passive sensors are analyzed and compared. For the most appropriated concept an optimization was made and theoretical performances in terms of number of detection versus class of diameter were calculated. Finally we give some preliminary physical sensor features to illustrate the concept (weight, volume, consumption,…).

  20. Innovative Methodology for Detection of Fracture-Controlled Sweet Spots in the Northern Appalachian Basin

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Jacobi, Rober

    2007-03-31

    This Topical Report (#6 of 9) consists of the figures 3.6-13 to (and including) 3.6-18 (and appropriate figure captions) that accompany the Final Technical Progress Report entitled: "Fracture-Controlled Sweet Spots in the Northern Appalachian Basin” for DOE/NETL Award DE-AC26-00NT40698.

  1. Final Technical Report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Glasser, Alan H.

    Final technical report on DE-SC0016106. This is the final technical report for a portion of the multi-institutional CEMM project. This report is centered around 3 publications and a seminar presentation, which have been submitted to E-Link.

  2. 10 CFR 52.157 - Contents of applications; technical information in final safety analysis report.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ...; technical information in final safety analysis report. The application must contain a final safety analysis...) Information sufficient to demonstrate compliance with the applicable requirements regarding testing, analysis... 10 Energy 2 2013-01-01 2013-01-01 false Contents of applications; technical information in final...

  3. 10 CFR 52.157 - Contents of applications; technical information in final safety analysis report.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ...; technical information in final safety analysis report. The application must contain a final safety analysis...) Information sufficient to demonstrate compliance with the applicable requirements regarding testing, analysis... 10 Energy 2 2012-01-01 2012-01-01 false Contents of applications; technical information in final...

  4. 10 CFR 52.157 - Contents of applications; technical information in final safety analysis report.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ...; technical information in final safety analysis report. The application must contain a final safety analysis...) Information sufficient to demonstrate compliance with the applicable requirements regarding testing, analysis... 10 Energy 2 2014-01-01 2014-01-01 false Contents of applications; technical information in final...

  5. 10 CFR 52.157 - Contents of applications; technical information in final safety analysis report.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ...; technical information in final safety analysis report. The application must contain a final safety analysis...) Information sufficient to demonstrate compliance with the applicable requirements regarding testing, analysis... 10 Energy 2 2011-01-01 2011-01-01 false Contents of applications; technical information in final...

  6. Henry Taube and Coordination Chemistry

    Science.gov Websites

    Shifts Caused by Cr++ in Aqueous Solutions, DOE Technical Report, 1962 Reactions of Solvated Ions Final Report, DOE Technical Report, 1962 Isotopic Discrimination of Some Solutes in Liquid Ammonia, DOE Technical Report, 1966 Final Technical Report of Research, DOE Technical Report, 1972 Top Additional Web

  7. George A. Olah, Carbocation and Hydrocarbon Chemistry

    Science.gov Websites

    . Final Technical Report. [HF:BF{sub 2}/H{sub 2}] , DOE Technical Report, 1980 Superacid Catalyzed Coal Conversion Chemistry. 1st and 2nd Quarterly Technical Progress Reports, September 1, 1983-March 30, 1984 , DOE Technical Report, 1984 Superacid Catalyzed Coal Conversion Chemistry. Final Technical Report

  8. 77 FR 46306 - Fluxapyroxad; Pesticide Tolerances Technical Amendment

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-03

    ...; Pesticide Tolerances Technical Amendment AGENCY: Environmental Protection Agency (EPA). ACTION: Final rule; technical amendment. SUMMARY: EPA issued a final rule in the Federal Register of May 14, 2012, concerning.... Inadvertently, the terminology for the oilseed crop group and for dried plums was incorrect. This technical...

  9. Chemical warfare agent detection: a review of current trends and future perspective.

    PubMed

    Pacsial-Ong, Eden Joy; Aguilar, Zoraida P

    2013-01-01

    The World Health Organization recommends countries to create a public health system that can respond to the deliberate release of chemical warfare agents (CWAs). Procedures for preparedness, response, decontamination protocols and medical countermeasures against CWA attacks are described. Known CWAs, including their properties and pharmacological consequences upon exposure, are tabulated and discussed. Requirements imposed on detection systems by various applications and environmental needs are presented in order to assess the devices for detection and identification of specific CWAs. The review surveys current and near-term detection technologies and equipments, as well as devices that are currently available to the military and civilian first responders. Brief technical discussions of several detection technologies are presented, with emphasis placed in the principles of detection. Finally, enabling technologies that form the basis for advanced sensing systems and devices are described.

  10. 32 CFR 37.895 - How is the final performance report to be sent to the Defense Technical Information Center?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... How is the final performance report to be sent to the Defense Technical Information Center? (a... 32 National Defense 1 2014-07-01 2014-07-01 false How is the final performance report to be sent to the Defense Technical Information Center? 37.895 Section 37.895 National Defense Department of...

  11. 32 CFR 37.895 - How is the final performance report to be sent to the Defense Technical Information Center?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... How is the final performance report to be sent to the Defense Technical Information Center? (a... 32 National Defense 1 2011-07-01 2011-07-01 false How is the final performance report to be sent to the Defense Technical Information Center? 37.895 Section 37.895 National Defense Department of...

  12. 32 CFR 37.895 - How is the final performance report to be sent to the Defense Technical Information Center?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... How is the final performance report to be sent to the Defense Technical Information Center? (a... 32 National Defense 1 2013-07-01 2013-07-01 false How is the final performance report to be sent to the Defense Technical Information Center? 37.895 Section 37.895 National Defense Department of...

  13. 32 CFR 37.895 - How is the final performance report to be sent to the Defense Technical Information Center?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 32 National Defense 1 2012-07-01 2012-07-01 false How is the final performance report to be sent to the Defense Technical Information Center? 37.895 Section 37.895 National Defense Department of... How is the final performance report to be sent to the Defense Technical Information Center? (a...

  14. 76 FR 18624 - Research, Technical Assistance and Training Programs: Notice of Final Circular

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-04

    ... to FTA Circular 6100.1D, Research and Technical Assistance Training Program: Application Instructions... DEPARTMENT OF TRANSPORTATION Federal Transit Administration Research, Technical Assistance and Training Programs: Notice of Final Circular AGENCY: Federal Transit Administration (FTA), DOT. ACTION...

  15. Minnesota Deaf-Blind Technical Assistance Project. Final Report.

    ERIC Educational Resources Information Center

    Kloos, Eric

    This final report describes activities and accomplishments of the 3-year federally supported Minnesota Deaf-Blind Technical Assistance Project. The project provided training and technical assistance, information sharing, and support services to families of children with deaf-blindness. Activities and accomplishments included: collaboration with…

  16. 75 FR 56857 - Pilot, Flight Instructor, and Pilot School Certification

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-17

    ... of part 141. Discussion of Technical Amendment Section 141.5(d) establishes the quality of training... Certification AGENCY: Federal Aviation Administration, DOT. ACTION: Final rule; technical amendment. SUMMARY: The Federal Aviation Administration (FAA) is making minor technical changes to a final rule published...

  17. Simulation and experiment for the inspection of stainless steel bolts in servicing using an ultrasonic phased array

    NASA Astrophysics Data System (ADS)

    Chen, Jinzhong; He, Renyang; Kang, Xiaowei; Yang, Xuyun

    2015-10-01

    The non-destructive testing of small-sized (M12-M20) stainless steel bolts in servicing is always a technical problem. This article focuses on the simulation and experimental research of stainless steel bolts with an artificial defect reflector using ultrasonic phased array inspection. Based on the observation of the sound field distribution of stainless steel bolts in ultrasonic phased array as well as simulation modelling and analysis of the phased array probes' detection effects with various defect sizes, different artificial defect reflectors of M16 stainless steel bolts are machined in reference to the simulation results. Next, those bolts are tested using a 10-wafer phased array probe with 5 MHz. The test results finally prove that ultrasonic phased array can detect 1-mm cracks in diameter with different depths of M16 stainless steel bolts and a metal loss of Φ1 mm of through-hole bolts, which provides technical support for future non-destructive testing of stainless steel bolts in servicing.

  18. In-Vivo Proton Magnetic Resonance Spectroscopy of 2-Hydroxyglutarate in Isocitrate Dehydrogenase-Mutated Gliomas: A Technical Review for Neuroradiologists.

    PubMed

    Kim, Hyeonjin; Kim, Sungjin; Lee, Hyeong Hun; Heo, Hwon

    2016-01-01

    The diagnostic and prognostic potential of an onco-metabolite, 2-hydroxyglutarate (2HG) as a proton magnetic resonance spectroscopy (1H-MRS) detectable biomarker of the isocitrate dehydrogenase (IDH)-mutated (IDH-MT) gliomas has drawn attention of neuroradiologists recently. However, due to severe spectral overlap with background signals, quantification of 2HG can be very challenging. In this technical review for neuroradiologists, first, the biochemistry of 2HG and its significance in the diagnosis of IDH-MT gliomas are summarized. Secondly, various 1H-MRS methods used in the previous studies are outlined. Finally, wereview previous in vivo studies, and discuss the current status of 1H-MRS in the diagnosis of IDH-MT gliomas.

  19. 77 FR 29247 - Federal Motor Vehicle Safety Standards; Occupant Crash Protection

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-17

    ...). ACTION: Final rule; technical amendments. SUMMARY: This final rule makes technical amendments to Federal... advanced air bag requirements. As written now, the general warning label requirements contain an explicit... equipment requirements for restraint systems. This document makes technical amendments to several of the...

  20. Clinical outcome of double crown-retained implant overdentures with zirconia primary crowns

    PubMed Central

    Buergers, Ralf; Ziebolz, Dirk; Roediger, Matthias

    2015-01-01

    PURPOSE This retrospective study aims at the evaluation of implant-supported overdentures (IODs) supported by ceramo-galvanic double crowns (CGDCs: zirconia primary crowns + galvano-formed secondary crown). MATERIALS AND METHODS In a private practice, 14 patients were restored with 18 IODs (mandible: 11, maxilla: 7) retained by CGDCs on 4 - 8 implants and annually evaluated for technical and/or biological failures/complications. RESULTS One of the 86 inserted implants failed during the healing period (cumulative survival rate (CSR) implants: 98.8%). During the prosthetic functional period (mean: 5.9 ± 2.2 years), 1 implant demonstrated an abutment fracture (CSR-abutments: 98.2%), and one case of peri-implantitis was detected. All IODs remained in function (CSR-denture: 100%). A total of 15 technical complications required interventions to maintain function (technical complication rate: 0.178 treatments/patients/year). CONCLUSION Considering the small sample size, the use of CGDCs for the attachment of IODs is possible without an increased risk of technical complications. However, for a final evaluation, results from a larger cohort are required. PMID:26330981

  1. Vehicle Integrated Prognostic Reasoner (VIPR) Final Report

    NASA Technical Reports Server (NTRS)

    Bharadwaj, Raj; Mylaraswamy, Dinkar; Cornhill, Dennis; Biswas, Gautam; Koutsoukos, Xenofon; Mack, Daniel

    2013-01-01

    A systems view is necessary to detect, diagnose, predict, and mitigate adverse events during the flight of an aircraft. While most aircraft subsystems look for simple threshold exceedances and report them to a central maintenance computer, the vehicle integrated prognostic reasoner (VIPR) proactively generates evidence and takes an active role in aircraft-level health assessment. Establishing the technical feasibility and a design trade-space for this next-generation vehicle-level reasoning system (VLRS) is the focus of our work.

  2. Phase magnification by two-axis countertwisting for detection-noise robust interferometry

    NASA Astrophysics Data System (ADS)

    Anders, Fabian; Pezzè, Luca; Smerzi, Augusto; Klempt, Carsten

    2018-04-01

    Entanglement-enhanced atom interferometry has the potential of surpassing the standard quantum limit and eventually reaching the ultimate Heisenberg bound. The experimental progress is, however, hindered by various technical noise sources, including the noise in the detection of the output quantum state. The influence of detection noise can be largely overcome by exploiting echo schemes, where the entanglement-generating interaction is repeated after the interferometer sequence. Here, we propose an echo protocol that uses two-axis countertwisting as the main nonlinear interaction. We demonstrate that the scheme is robust to detection noise and its performance is superior compared to the already demonstrated one-axis twisting echo scheme. In particular, the sensitivity maintains the Heisenberg scaling in the limit of a large particle number. Finally, we show that the protocol can be implemented with spinor Bose-Einstein condensates. Our results thus outline a realistic approach to mitigate the detection noise in quantum-enhanced interferometry.

  3. 77 FR 30512 - Native American Career and Technical Education Program; Final Waivers and Extension of Project...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-23

    ... DEPARTMENT OF EDUCATION Native American Career and Technical Education Program; Final Waivers and... American Career and Technical Education Program Catalog of Federal Domestic Assistance (CFDA) Number: 84.101A. SUMMARY: For 60-month projects funded in fiscal year (FY) 2007 under the Native American Career...

  4. 48 CFR 1852.235-73 - Final Scientific and Technical Reports.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Final Scientific and Technical Reports. 1852.235-73 Section 1852.235-73 Federal Acquisition Regulations System NATIONAL..., including recommendations and conclusions based on the experience and results obtained. The final report...

  5. Coosa River Storage Annex, Talladega, Alabama Environmental Investigation, Final Management and Resources Utilization Plan

    DTIC Science & Technology

    1991-02-01

    to adequately assess the health and environmental risks associated with the closure and transfer of the Annex forI other use; and 3) identification of...1990); Draft Final Technical Plan, Draft Final Sampling Design Plan and Draft Final Health and Safety Plan, USATHAMA, June 1990. 2.1.2 Draft Final...Final Technical Plan, Sampling Design Plan and Health and Safety Plan) supplied by USATHAMA. The estimate may be revised, with USATHAMA approval, as

  6. Final Technical Report for ELF/VLF Electromagnetic Detection and Characterization of Deeply Buried Targets

    DTIC Science & Technology

    1998-06-22

    remote (e.g. HAARP /HIPAS), and natural sources (e.g. external noise); b) model the perturbed fields due to the specified underground structures...examined in this study are of three types • Remote man-made sources, e.g. HAARP /HIPAS • Local sources, e.g. metal-detector loop • Natural sources, e.g...The High Power Auroral Stimulation Observatory (HIPAS) and the High Frequency Active Auroral Research Program ( HAARP ) are capable of exciting plasma

  7. Recommendations for describing statistical studies and results in general readership science and engineering journals.

    PubMed

    Gardenier, John S

    2012-12-01

    This paper recommends how authors of statistical studies can communicate to general audiences fully, clearly, and comfortably. The studies may use statistical methods to explore issues in science, engineering, and society or they may address issues in statistics specifically. In either case, readers without explicit statistical training should have no problem understanding the issues, the methods, or the results at a non-technical level. The arguments for those results should be clear, logical, and persuasive. This paper also provides advice for editors of general journals on selecting high quality statistical articles without the need for exceptional work or expense. Finally, readers are also advised to watch out for some common errors or misuses of statistics that can be detected without a technical statistical background.

  8. 77 FR 50589 - Agreements and Memoranda of Understanding Between the Food and Drug Administration and Other...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-22

    ...: Final rule. SUMMARY: This final rule makes technical changes that will update a requirement that many of the written agreements and memoranda of understanding (MOUs) between the Food and Drug Administration.... This final rule, accordingly, eliminates it. We are making these technical changes to conserve Agency...

  9. 77 FR 30514 - Native Hawaiian Career and Technical Education Program; Final Waiver and Extension of Project Period

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-23

    ... DEPARTMENT OF EDUCATION Native Hawaiian Career and Technical Education Program; Final Waiver and.... ACTION: Notice. Overview Information Final Waiver and Extension of Project Period for the Native Hawaiian.... SUMMARY: For 36-month projects funded in fiscal year (FY) 2009 under the Native Hawaiian Career and...

  10. Large aperture and wide field of view space telescope for the detection of ultra high energy cosmic rays and neutrinos

    NASA Astrophysics Data System (ADS)

    Mazzinghi, Piero; Bratina, Vojko; Gambicorti, Lisa; Simonetti, Francesca; Zuccaro Marchi, Alessandro

    2017-11-01

    New technologies are proposed for large aperture and wide Field of View (FOV) space telescopes dedicated to detection of Ultra High Energy Cosmic Rays and Neutrinos flux, through observation of fluorescence traces in atmosphere and diffused Cerenkov signals. The presented advanced detection system is a spaceborne LEO telescope, with better performance than ground-based observatories, detecting up to 103 - 104 events/year. Different design approaches are implemented, all with very large FOV and focal surface detectors with sufficient segmentation and time resolution to allow precise reconstructions of the arrival direction. In particular, two Schmidt cameras are suggested as an appropriate solution to match most of the optical and technical requirements: large FOV, low f/#, reduction of stray light, optionally flat focal surface, already proven low-cost construction technologies. Finally, a preliminary proposal of a wideFOV retrofocus catadioptric telescope is explained.

  11. Historical Techniques of Lie Detection

    PubMed Central

    Vicianova, Martina

    2015-01-01

    Since time immemorial, lying has been a part of everyday life. For this reason, it has become a subject of interest in several disciplines, including psychology. The purpose of this article is to provide a general overview of the literature and thinking to date about the evolution of lie detection techniques. The first part explores ancient methods recorded circa 1000 B.C. (e.g., God’s judgment in Europe). The second part describes technical methods based on sciences such as phrenology, polygraph and graphology. This is followed by an outline of more modern-day approaches such as FACS (Facial Action Coding System), functional MRI, and Brain Fingerprinting. Finally, after the familiarization with the historical development of techniques for lie detection, we discuss the scope for new initiatives not only in the area of designing new methods, but also for the research into lie detection itself, such as its motives and regulatory issues related to deception. PMID:27247675

  12. Detection of Gunshot Residues Using Mass Spectrometry

    PubMed Central

    Blanes, Lucas; Cole, Nerida; Doble, Philip; Roux, Claude

    2014-01-01

    In recent years, forensic scientists have become increasingly interested in the detection and interpretation of organic gunshot residues (OGSR) due to the increasing use of lead- and heavy metal-free ammunition. This has also been prompted by the identification of gunshot residue- (GSR-) like particles in environmental and occupational samples. Various techniques have been investigated for their ability to detect OGSR. Mass spectrometry (MS) coupled to a chromatographic system is a powerful tool due to its high selectivity and sensitivity. Further, modern MS instruments can detect and identify a number of explosives and additives which may require different ionization techniques. Finally, MS has been applied to the analysis of both OGSR and inorganic gunshot residue (IGSR), although the “gold standard” for analysis is scanning electron microscopy with energy dispersive X-ray microscopy (SEM-EDX). This review presents an overview of the technical attributes of currently available MS and ionization techniques and their reported applications to GSR analysis. PMID:24977168

  13. 2005 v4.3 Technical Support Document

    EPA Pesticide Factsheets

    Emissions Modeling for the Final Mercury and Air Toxics Standards Technical Support Document describes how updated 2005 NEI, version 2 emissions were processed for air quality modeling in support of the final Mercury and Air Toxics Standards (MATS).

  14. The Center for Space Telemetering and Telecommunications Systems

    NASA Technical Reports Server (NTRS)

    Horan, S.; DeLeon, P.; Borah, D.; Lyman, R.

    2003-01-01

    This report comprises the final technical report for the research grant 'Center for Space Telemetering and Telecommunications Systems' sponsored by the National Aeronautics and Space Administration's Goddard Space Flight Center. The grant activities are broken down into the following technology areas: (1) Space Protocol Testing; (2) Autonomous Reconfiguration of Ground Station Receivers; (3) Satellite Cluster Communications; and (4) Bandwidth Efficient Modulation. The grant activity produced a number of technical reports and papers that were communicated to NASA as they were generated. This final report contains the final summary papers or final technical report conclusions for each of the project areas. Additionally, the grant supported students who made progress towards their degrees while working on the research.

  15. Promotion of the Equal Access of Girls and Women to Technical and Vocational Education. Studies on Technical and Vocational Education 7.

    ERIC Educational Resources Information Center

    United Nations Educational, Scientific, and Cultural Organization, Paris (France).

    This monograph includes the final report of the International Expert Meeting on the Promotion of Equal Access of Girls and Women to Technical and Vocational Education (TVE) held in Seoul, Republic of Korea, and country discussion papers. The final report is composed of an introduction that proposes that many Member States require special measures…

  16. Air Quality Modeling Technical Support Document for the Final Cross State Air Pollution Rule Update

    EPA Pesticide Factsheets

    In this technical support document (TSD) we describe the air quality modeling performed to support the final Cross State Air Pollution Rule for the 2008 ozone National Ambient Air Quality Standards (NAAQS).

  17. 7 CFR 614.7 - Preliminary technical determinations.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 6 2010-01-01 2010-01-01 false Preliminary technical determinations. 614.7 Section... Preliminary technical determinations. (a) A preliminary technical determination becomes final 30 days after... purpose of gathering additional information and discussing the facts relating to the preliminary technical...

  18. Technical specifications of low-frequency radio identification bedload tracking from field experiments: Differences in antennas, tags and operators

    NASA Astrophysics Data System (ADS)

    Arnaud, F.; Piégay, H.; Vaudor, L.; Bultingaire, L.; Fantino, G.

    2015-06-01

    Low-frequency passive integrated transponders (PIT tags) have been increasingly used for tracking bedload transport in gravel-bed rivers. Prior studies have reported high recovery rates in small streams, while recovery rates remained much lower in large systems, in large part because of the limited reading distance of the tags (< 1 m). Some laboratory tests have identified controlling factors for detection ranges (tag and antenna size, tag orientation, burial, submergence, etc.). Beyond these tests, improving our understanding of PIT tag functioning, using different equipment within different environments, is still needed in order to select the most suitable device for each geomorphic context. We address this knowledge gap with technical specifications for a low-frequency radio identification (RFID) device by working for the first time with real fluvial constraints, i.e., the gravel deposits and the aquatic channel. The three-dimensional detection envelopes of two types of tags and three types of antennas are quantified as well as the effect of practices (interoperator bias, battery power) on the detection. The interoperator variability and the intertag variability can be considered as negligible. The influence of burial in dry and water-saturated sediment and the influence of water immersion are shown to be minor. Finally, we summarize practical implications for RFID bedload tracking through these experiments.

  19. Cybersecurity Intrusion Detection and Monitoring for Field Area Network: Final Report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Pietrowicz, Stanley

    This report summarizes the key technical accomplishments, industry impact and performance of the I2-CEDS grant entitled “Cybersecurity Intrusion Detection and Monitoring for Field Area Network”. Led by Applied Communication Sciences (ACS/Vencore Labs) in conjunction with its utility partner Sacramento Municipal Utility District (SMUD), the project accelerated research on a first-of-its-kind cybersecurity monitoring solution for Advanced Meter Infrastructure and Distribution Automation field networks. It advanced the technology to a validated, full-scale solution that detects anomalies, intrusion events and improves utility situational awareness and visibility. The solution was successfully transitioned and commercialized for production use as SecureSmart™ Continuous Monitoring. Discoveries made withmore » SecureSmart™ Continuous Monitoring led to tangible and demonstrable improvements in the security posture of the US national electric infrastructure.« less

  20. Programs of Study as a State Policy Mandate: A Longitudinal Study of the South Carolina Personal Pathways to Success Initiative. Final Technical Report: Major Findings and Implications

    ERIC Educational Resources Information Center

    Hammond, Cathy; Drew, Sam F.; Withington, Cairen; Griffith, Cathy; Swiger, Caroline M.; Mobley, Catherine; Sharp, Julia L.; Stringfield, Samuel C.; Stipanovic, Natalie; Daugherty, Lindsay

    2013-01-01

    This is the final technical report from the National Research Center for Career and Technical Education's (NRCCTE's) five-year longitudinal study of South Carolina's Personal Pathway to Success initiative, which was authorized by the state's Education and Economic Development Act (EEDA) in 2005. NRCCTE-affiliated researchers at the National…

  1. Direct Final Rule: Nonroad Diesel Technical Amendments and Tier 3 Technical Relief Provision

    EPA Pesticide Factsheets

    Rule making certain technical corrections to the rules establishing emission standards for nonroad diesel engines and amending those rules to provide manufacturers with a production technical relief provision for Tier 3 equipment.

  2. Arizona Deafblind Project, 1995-1999. Final Report.

    ERIC Educational Resources Information Center

    Arizona State School for the Deaf and Blind, Tucson.

    This final report describes accomplishments of the four-year federally funded Arizona Deafblind Project which attempted to: (1) identify all deafblind children in Arizona; (2) deliver technical assistance to families; (3) deliver technical assistance to service providers; and (4) enhance community oversight, coordination, and collaboration with…

  3. Joint Common Architecture Demonstration (JCA Demo) Final Report

    DTIC Science & Technology

    2016-07-28

    approach for implementing open systems [16], formerly known as the Modular Open Systems Approach (MOSA). OSA is a business and technical strategy to... TECHNICAL REPORT RDMR-AD-16-01 JOINT COMMON ARCHITECTURE DEMONSTRATION (JCA DEMO) FINAL REPORT Scott A. Wigginton... Modular Avionics .......................................................................... 5 E. Model-Based Engineering

  4. 76 FR 80226 - Technical Amendments

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-23

    ... final rule, effective upon publication. Generally, the Administrative Procedure Act (APA) requires a.... Additionally, the APA requires that a final rule must have a delayed effective date of 30 days from the date of... delayed effective date requirement under the APA. 5 U.S.C. 553(d)(3). Again the technical change conforms...

  5. "Type Ia Supernovae: Tools for Studying Dark Energy" Final Technical Report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Woosley, Stan; Kasen, Dan

    2017-05-10

    Final technical report for project "Type Ia Supernovae: Tools for the Study of Dark Energy" awarded jointly to scientists at the University of California, Santa Cruz and Berkeley, for computer modeling, theory and data analysis relevant to the use of Type Ia supernovae as standard candles for cosmology.

  6. 76 FR 50202 - National Technical Assistance and Dissemination Center for Children Who Are Deaf-Blind; Final...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-12

    ... DEPARTMENT OF EDUCATION [CFDA No. 84.326T] National Technical Assistance and Dissemination Center for Children Who Are Deaf-Blind; Final Extension of Project Period and Waiver AGENCY: Office of Special Education Programs, Office of Special Education and Rehabilitative Services, Department of...

  7. TADS Final Evaluation Report, 1980-81. Appendix S.

    ERIC Educational Resources Information Center

    Suarez, Tanya M.; And Others

    The document contains the final report of the Technical Assistance Development System (TADS), a program which provided technical assistance (TA) services to 53 Handicapped Children's Early Education Program (HCEEP) demonstration projects and 13 State Implementation Grants (SIGs). The evaluation report is divided into five sections. Section 1…

  8. Antarctic atmospheric infrasound. Final technical report, 1 July 1981-30 September 1984

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wilson, C.R.; McKibben, B.N.

    1986-11-01

    In order to monitor atmospheric infrasonic waves in the passband from 0.1 to 0.01 Hz a digital infrasonic detection system was installed in Antarctica on the Ross Ice shelf near McMurdo Station on McMurdo Sound. An array of seven infrasonic microphones subtending an area of about 35 sg km was operated in Windless Bight. The analog microphone data were telemetered to McMurdo station where the infrasonic date were digitized and subjected to on-line real-time analysis to detect traveling infrasonic waves with periods from 10 to 100 seconds. During the period of operation of the Antartic infrasonic observatory, hundreds of infrasonicmore » signals were detected in association with many natural sources such as the aurora australis, marine storm sea-air interactions, volcanic eruptions, mountain generated lee-wave effects, large meteors and auroral electrojet supersonic motions.« less

  9. End-to-End System Test of the Relative Precision and Stability of the Photometric Method for Detecting Earth-Size Extrasolar Planets

    NASA Technical Reports Server (NTRS)

    Dunham, Edward W.

    2000-01-01

    We developed the CCD camera system for the laboratory test demonstration and designed the optical system for this test. The camera system was delivered to Ames in April, 1999 with continuing support mostly in the software area as the test progressed. The camera system has been operating successfully since delivery. The optical system performed well during the test. The laboratory demonstration activity is now nearly complete and is considered to be successful by the Technical Advisory Group, which met on 8 February, 2000 at the SETI Institute. A final report for the Technical Advisory Group and NASA Headquarters will be produced in the next few months. This report will be a comprehensive report on all facets of the test including those covered under this grant. A copy will be forwarded, if desired, when it is complete.

  10. [Analysis of effect of prevention and control technique training of human important parasitic diseases in Jiangsu Province in 2017].

    PubMed

    Bi-Xian, Ni; Xiang-Zhen, Xu; Xiao-Ting, Wang; Ming-Xue, Sheng; Yang, Dai; Xiao-Lin, Jin

    2017-07-24

    To evaluate the effect of the prevention and control technique training of human important parasitic diseases for basic professional and technical personnel in Jiangsu Province in 2017. A workshop including theory courses and practical operations was carried out for the basic professional and technical personnel. At the end of the workshop, the effects were evaluated through the theoretical and microscopic examinations. There were 132 trainees from 13 cities, and all of them took part in the final examinations. The average score of total was 118.36. There were significant differences among different regions ( χ 2 = 13.38, P < 0.01). The pass rate of the theory test was 92.4% with the average score of 79.05. There were significant differences of theory scores among different regions ( χ 2 =14.51, P < 0.01). The theory score of Northern Jiangsu Province was significantly higher than the scores of Southern and Central Jiangsu Province ( P < 0.001, P = 0.009). The pass rate of microscopic examinations was 89.4% with the average score of 39.32. There was no significant difference of micro-scopic examination scores among different regions ( F = 2.37, P = 0.09). Among the total 7 species, the detection rate of Paragonimus westermani was the highest (75%) and the rates of Schistosoma japonicum and Fasciolopsis buski were only 51.5% and 54.5% respectively. The detection rates of eggs of Trichuris trichiura , unfertilized Ascaris lumbricoides , Clonorchis sinensis and Taenia solium were 71.2%, 65.9%, 72.7% and 72.0% respectively. The training course has promoted the capability of prevention and control of parasitic diseases for basic technical personnel. Also it provides the technical supports for parasitic disease monitoring, control and risk assessment in the next step.

  11. New antibody and immunoassay pretreatment strategy to screen polychlorinated biphenyls in Korean transformer oil.

    PubMed

    Terakado, Shingo; Ohmura, Naoya; Park, Seok-Un; Lee, Seung-Min; Glass, Thomas R

    2013-01-01

    Development and modifications are described that expand the application of an immunoassay from the detection of Kanechlors (Japanese technical PCBs mixtures) to the detection of Aroclors (U. S. technical PCB mixtures, used in Korea) in contaminated Korean transformer oil. The first necessary modification was the development of a new antibody with a reactivity profile favorable for Aroclors. The second modification was the addition of a second column to the solid-phase extraction method to reduce assay interference caused by the Korean oil matrix. The matrix interference is suspected to be caused by the presence of synthetic oils (or similar materials) present as contaminants. The modified assay was validated by comparison to high-resolution gas chromatography/high-resolution mass spectrometry analysis, and was shown to be tolerant of up to 10% of several common synthetic insulating oils. Finally the screening performance of the modified assay was evaluated using 500 used transformer oil samples of Korean origin, and was shown to have good performance in terms of false positive and false negative rates. This report provides evidence for the first establishment of immunoassay screening for Aroclor based PCB contamination in Korean transformer oil.

  12. Evaluation of different heating methods for the detection of boar taint by means of the human nose.

    PubMed

    Bekaert, K M; Aluwé, M; Vanhaecke, L; Heres, L; Duchateau, L; Vandendriessche, F; Tuyttens, F A M

    2013-05-01

    No automated detection system for boar taint detection is currently available, thus boar taint at the slaughterline can currently only be assessed using the singeing method (olfactory scoring). This study compares several heating methods (microwave, soldering iron and pyropen) and evaluates the effect of habituation, cleaning the soldering iron, singeing the fat twice in the same place, and variations in the technical procedures. All methods seem to be suitable for detecting boar taint but the choice of heating method for sensory scoring of boar taint depends on habituation of the trained assessor and specific conditions applied. The pyropen seems to be most suitable because it does not contact the fat and is easy to handle (wireless). Finally, the intensity score may also be influenced by: contamination from not cleaning the soldering iron, singeing the fat twice in the same place, and the effect of habituation. Copyright © 2013 Elsevier Ltd. All rights reserved.

  13. 78 FR 57264 - Final Waiver and Extension of the Project Period for the Technical Assistance Coordination Center

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-18

    ...: 84.326Z.] Final Waiver and Extension of the Project Period for the Technical Assistance Coordination... project period. SUMMARY: The Secretary waives the requirements in the Education Department General Administrative Regulations that generally prohibit project periods exceeding five years and extensions of project...

  14. 77 FR 16923 - Agreements and Memoranda of Understanding Between the Food and Drug Administration and Other...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-23

    ...: Direct final rule. SUMMARY: This direct final rule makes technical changes that will update a requirement that many of our written agreements and memoranda of understanding (MOUs) with other departments..., accordingly, eliminates it. We are making these technical changes to conserve Agency time and resources...

  15. 1988 Underground Storage Tanks; Technical Requirements; Final Rule and Underground Storage Tanks Containing Petroleum-Financial Responsibility Requirements and State Program Approval Objective; Final Rule

    EPA Pesticide Factsheets

    EPA's 1988 regulations concerning USTs are contained in 40 CFR Part 280, 40 CFR Part 281 and 40 CFR Parts 282.50-282.105 and divided into three sections: technical requirements, financial responsibility requirements, and state program approval objectives.

  16. PITTSBURGH TECHNICAL HEALTH TRAINING INSTITUTE DEMONSTRATION PROJECT. FINAL REPORT, VOLUME II.

    ERIC Educational Resources Information Center

    KISHKUNAS, LOUIS J.

    APPENDIXES TO THE "FINAL REPORT," VOLUME I (VT 005 511), ARE INCLUDED--(1) A SCHEMATIC REPRESENTATION OF CURRICULUM DEVELOPMENT, (2) TECHNICAL BEHAVIOR CHECKLISTS, (3) PERFORMANCE INVENTORY FORMS USED IN ON-THE-JOB OBSERVATIONS, (4) REPORT FORM FOR TYPICAL JOB BEHAVIOR OF EMPLOYEE, (5) COOPERATING AREA HEALTH INSTITUTIONS, (6) TABLES OF Z SCORES…

  17. Invention and Writing in Technical Work: Representing the Object.

    ERIC Educational Resources Information Center

    Winsor, Dorothy A.

    1994-01-01

    Describes the way invention is relevant to the practice of technical writing. Studies three engineering students engaged in a real-world project. Shows how the students' technical work and invention for the final report were simultaneous activities. Claims that invention for and through writing overlaps with technical invention. (HB)

  18. Project T.E.A.M. (Technical Education Advancement Modules). Final Report.

    ERIC Educational Resources Information Center

    Greenville Technical Coll., SC.

    Project TEAM (Technical Education Advancement Modules), a cooperative demonstration program for high technology training, created an introductory technical training program and a consumer education package emphasizing the benefits of technical training. The curriculum and training focus of the project began with an assessment of employee needs in…

  19. 77 FR 39623 - Airworthiness Standards: Aircraft Engines; Technical Amendment

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-05

    ...] Airworthiness Standards: Aircraft Engines; Technical Amendment AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule; technical amendment. SUMMARY: This amendment clarifies aircraft engine... from applicants requesting FAA engine type certifications and aftermarket certifications, such as...

  20. 7 CFR 652.36 - Appeal of decertification decisions.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... technical service provider's written appeal, the Chief or his designee, will make a final determination, in... CONSERVATION SERVICE, DEPARTMENT OF AGRICULTURE SUPPORT ACTIVITIES TECHNICAL SERVICE PROVIDER ASSISTANCE... of the State Conservationist's decertification determination, the technical service provider may...

  1. Capturing Cognitive Fingerprints for Active Authentication

    DTIC Science & Technology

    2014-10-01

    CAPTURING COGNITIVE FINGERPRINTS FOR ACTIVE AUTHENTICATION IOWA STATE UNIVERSITY OF SCIENCE & TECHNOLOGY OCTOBER 2014 FINAL TECHNICAL REPORT...REPORT TYPE FINAL TECHNICAL REPORT 3. DATES COVERED (From - To) SEP 2013 – APR 2014 4. TITLE AND SUBTITLE CAPTURING COGNITIVE FINGERPRINTS FOR ACTIVE...The project ended before the IRB application was approved. 15. SUBJECT TERMS Active Authentication, Cognitive Fingerprints , Biometric Modalities

  2. Application of Communications Satellites to Educational Development. Final Technical Report, September 1, 1969-August 31, 1975.

    ERIC Educational Resources Information Center

    Morgan, Robert P.

    Research is summarized in a brief final report built around a four-section bibliography. The first section lists periodic progress reports and articles which provide an overview of the program, including articles which pertain primarily to educational rather than technical aspects of satellite utilization. Theses carried out in the fields of…

  3. Head Start Impact Study. Technical Report

    ERIC Educational Resources Information Center

    Puma, Michael; Bell, Stephen; Cook, Ronna; Heid, Camilla; Shapiro, Gary; Broene, Pam; Jenkins, Frank; Fletcher, Philip; Quinn, Liz; Friedman, Janet; Ciarico, Janet; Rohacek, Monica; Adams, Gina; Spier, Elizabeth

    2010-01-01

    This Technical Report is designed to provide technical detail to support the analysis and findings presented in the "Head Start Impact Study Final Report" (U.S. Department of Health and Human Services, January 2010). Chapter 1 provides an overview of the Head Start Impact Study and its findings. Chapter 2 provides technical information on the…

  4. Matching Community and Technical College Professional/Technical Education Capacity to Employer Demand. Final Report.

    ERIC Educational Resources Information Center

    Sommers, Paul; Heg, Deena

    A project was conducted to improve the state of Washington's community and technical college system by developing and using an improved occupational forecasting system to assess and respond to education and training needs. First, long-term occupational forecast data from Washington's Employment Security Department were matched with technical and…

  5. 75 FR 5784 - Guidance on Preparation of Market-Based Rate Filings and Electric Quarterly Reports by Public...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-04

    ... Preparation of Market-Based Rate Filings and Electric Quarterly Reports by Public Utilities; Notice of Technical Conference January 28, 2010. Take notice that Commission staff will convene a technical conference... final agenda of the technical conference. The March 3, 2010 technical conference will focus on the...

  6. A Revision of Technical Mathematics Based on the NCTM Standards. Final Report.

    ERIC Educational Resources Information Center

    Near, Barbara

    Between 1993 and 1996, Henry Ford Community College (Michigan) worked with business, industry, and technical instructors to revise their Technical Mathematics program in accordance with the National Council of Teachers of Mathematics (NCTM) Standards. The purpose of the project was to restructure the technical math curriculum and create a context…

  7. 76 FR 11327 - Technical Amendments to Rule 17a-8: Financial Recordkeeping and Reporting of Currency and Foreign...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-02

    ... SECURITIES AND EXCHANGE COMMISSION 17 CFR Part 240 [Release No. 34-63949] Technical Amendments to...: Securities and Exchange Commission. ACTION: Final rule; technical amendments. SUMMARY: The Securities and Exchange Commission (``Commission'') is adopting technical amendments to Rule 17a-8 under the Securities...

  8. Final priority; technical assistance to improve state data capacity--National Technical Assistance Center to improve state capacity to accurately collect and report IDEA data. Final priority.

    PubMed

    2013-05-20

    The Assistant Secretary for Special Education and Rehabilitative Services announces a priority under the Technical Assistance to Improve State Data Capacity program. The Assistant Secretary may use this priority for competitions in fiscal year (FY) 2013 and later years. We take this action to focus attention on an identified national need to provide technical assistance (TA) to States to improve their capacity to meet the data collection and reporting requirements of the Individuals with Disabilities Education Act (IDEA). We intend this priority to establish a TA center to improve State capacity to accurately collect and report IDEA data (Data Center).

  9. Technical Evaluation Motor No. 10 (TEM-10)

    NASA Technical Reports Server (NTRS)

    1993-01-01

    Technical Evaluation Motor No. 10 (TEM-10) was static fired on 27 Apr. 1993 at the Thiokol Corporation full-scale motor static test bay, T-24. This final test report documents the procedures, performance, and results of the static test firing of TEM-10. All observations, discussions, conclusions, and recommendations contained are final. Included is a presentation and discussion of TEM-10 performance, anomalies, and test results in concurrence with the objectives outlined in CTP-0110, Revision D, Space Shuttle Technical Evaluation Motor No. 10 (TEM-10) Static Fire Test Plan.

  10. Final priority; Technical Assistance on State Data Collection--IDEA Data Management Center. Final priority.

    PubMed

    2014-08-05

    The Assistant Secretary for the Office of Special Education and Rehabilitative Services (OSERS) announces a priority under the Technical Assistance on State Data Collection program. The Assistant Secretary may use this priority for competitions in fiscal year (FY) 2014 and later years. We take this action to fund a cooperative agreement to establish and operate an IDEA Data Management Center (Center) that will provide technical assistance (TA) to improve the capacity of States to meet the data collection requirements of the Individuals with Disabilities Education Act (IDEA).

  11. Technical Topic 3.2.2.d Bayesian and Non-Parametric Statistics: Integration of Neural Networks with Bayesian Networks for Data Fusion and Predictive Modeling

    DTIC Science & Technology

    2016-05-31

    and included explosives such as TATP, HMTD, RDX, RDX, ammonium nitrate , potassium perchlorate, potassium nitrate , sugar, and TNT. The approach...Distribution Unlimited UU UU UU UU 31-05-2016 15-Apr-2014 14-Jan-2015 Final Report: Technical Topic 3.2.2. d Bayesian and Non- parametric Statistics...of Papers published in non peer-reviewed journals: Final Report: Technical Topic 3.2.2. d Bayesian and Non-parametric Statistics: Integration of Neural

  12. Final June Revisions Rule Significant Contribution Assessment TSD

    EPA Pesticide Factsheets

    This Technical Support Document (TSD) presents quantitative assessments of the relationship between the final February revisions to the Transport Rule, the final June revisions rule, and the original analysis conducted for the final Transport Rule.

  13. Develop a Comprehensive Technical Training and Data Collection Program for Structural Welders and Fitters: Technical Proposal

    DTIC Science & Technology

    2006-05-30

    implementation Final Report 4 TECHNICAL PLAN AND RESULTS Task 1: Initiate the Project Management System Two senior NGSS production management...1 Technical Plan and Results...Third the system is hosted on a handheld unit which provides the foremen with an efficient daily planning tool. The Pilot System which entails

  14. Laser Technician Associate Degree Program. A Proposal Submitted to Wisconsin State Board of Vocational, Technical, and Adult Education. (Curriculum Development.) Final Report.

    ERIC Educational Resources Information Center

    North Central Technical Inst., Wausau, WI.

    This final report contains the program proposal with supporting data for developing curriculum materials for and implementing an associate-degree laser technology program at the North Central Technical Institute. The proposal outline provides this information: (1) objectives for the program designed to prepare a technician to safely operate,…

  15. California Deaf-Blind Services Final Report, October 1, 1995-September 30, 1999 [and] October 1, 1999-June 30, 2000 (No Cost Extension).

    ERIC Educational Resources Information Center

    Goertz, Lori; Franklin, Barbara

    This final report describes the activities and outcomes of the California Deaf-Blind Services (CDBS) program, a regionally based, family focused technical assistance and training project designed to improve services to children with deaf-blindness. The project conducted the following activities: (1) provided technical assistance to families and…

  16. New Jersey Technical Assistance Project (N.J. TAP): "Educational Resources and Support Services on Behalf of Children with Multiple Sensory Impairment." Final Report.

    ERIC Educational Resources Information Center

    New Jersey State Dept. of Education, Trenton.

    This final report describes activities and accomplishments of the New Jersey Technical Assistance Project, a project to improve educational resources and support services for students with multiple sensory impairment (deaf-blindness). Activities and accomplishments are presented in a tabular format for each project goal and objective. The project…

  17. 78 FR 77563 - Technical Amendments

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-24

    ... NATIONAL CREDIT UNION ADMINISTRATION 12 CFR Parts 700, 701, and 704 RIN 3133-AE33 Technical Amendments AGENCY: National Credit Union Administration (NCUA). ACTION: Final rule. SUMMARY: The NCUA Board... credit unions. The technical amendments conform the regulations to a recent policy change adopted by the...

  18. 75 FR 33682 - Export Administration Regulations; Technical Amendments

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-15

    ...-01] RIN 0694-AE93 Export Administration Regulations; Technical Amendments AGENCY: Bureau of Industry... Bureau of Industry and Security (BIS) makes a technical amendment to the Export Administration... review of final decisions and orders issued in BIS export control administrative enforcement proceedings...

  19. 78 FR 41331 - Defense Federal Acquisition Regulation Supplement; Technical Amendments

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-10

    ... DEPARTMENT OF DEFENSE Defense Acquisition Regulations System 48 CFR Part 225 Defense Federal Acquisition Regulation Supplement; Technical Amendments AGENCY: Defense Acquisition Regulations System, Department of Defense (DoD). ACTION: Final rule. SUMMARY: DoD is making technical amendment to the Defense...

  20. RNase H-assisted RNA-primed rolling circle amplification for targeted RNA sequence detection.

    PubMed

    Takahashi, Hirokazu; Ohkawachi, Masahiko; Horio, Kyohei; Kobori, Toshiro; Aki, Tsunehiro; Matsumura, Yukihiko; Nakashimada, Yutaka; Okamura, Yoshiko

    2018-05-17

    RNA-primed rolling circle amplification (RPRCA) is a useful laboratory method for RNA detection; however, the detection of RNA is limited by the lack of information on 3'-terminal sequences. We uncovered that conventional RPRCA using pre-circularized probes could potentially detect the internal sequence of target RNA molecules in combination with RNase H. However, the specificity for mRNA detection was low, presumably due to non-specific hybridization of non-target RNA with the circular probe. To overcome this technical problem, we developed a method for detecting a sequence of interest in target RNA molecules via RNase H-assisted RPRCA using padlocked probes. When padlock probes are hybridized to the target RNA molecule, they are converted to the circular form by SplintR ligase. Subsequently, RNase H creates nick sites only in the hybridized RNA sequence, and single-stranded DNA is finally synthesized from the nick site by phi29 DNA polymerase. This method could specifically detect at least 10 fmol of the target RNA molecule without reverse transcription. Moreover, this method detected GFP mRNA present in 10 ng of total RNA isolated from Escherichia coli without background DNA amplification. Therefore, this method can potentially detect almost all types of RNA molecules without reverse transcription and reveal full-length sequence information.

  1. Final Revisions Rule Significant Contribution Assessment TSD

    EPA Pesticide Factsheets

    This Technical Support Document (TSD) presents quantitative assessments of the relationship between final revisions to the Transport Rule and the original analysis conducted for the final Transport Rule.

  2. Weak Value Amplification is Suboptimal for Estimation and Detection

    NASA Astrophysics Data System (ADS)

    Ferrie, Christopher; Combes, Joshua

    2014-01-01

    We show by using statistically rigorous arguments that the technique of weak value amplification does not perform better than standard statistical techniques for the tasks of single parameter estimation and signal detection. Specifically, we prove that postselection, a necessary ingredient for weak value amplification, decreases estimation accuracy and, moreover, arranging for anomalously large weak values is a suboptimal strategy. In doing so, we explicitly provide the optimal estimator, which in turn allows us to identify the optimal experimental arrangement to be the one in which all outcomes have equal weak values (all as small as possible) and the initial state of the meter is the maximal eigenvalue of the square of the system observable. Finally, we give precise quantitative conditions for when weak measurement (measurements without postselection or anomalously large weak values) can mitigate the effect of uncharacterized technical noise in estimation.

  3. 75 FR 15342 - Advisory Committees; Technical Amendment

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-29

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration 21 CFR Part 14 [Docket No. FDA-2010-N-0001] Advisory Committees; Technical Amendment Agency: Food and Drug Administration, HHS. ACTION: Final rule; technical amendment. SUMMARY: The Food and Drug Administration (FDA) is amending its...

  4. 2012 Technical Corrections Fact Sheet

    EPA Pesticide Factsheets

    Final Rule: 2012 Technical Corrections, Clarifying and Other Amendments to theGreenhouse Gas Reporting Rule, and Confidentiality Determinations for Certain DataElements of the Fluorinated Gas Source Category

  5. Evaluation of Routine Atmospheric Sounding Measurements using Unmanned Systems (ERASMUS): Final Technical Report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    de Boer, Gijs; Lawrence, Dale; Palo, Scott

    2017-03-29

    This final technical report details activities undertaken as part of the referenced project. Included is information on the preparation of aircraft for deployment to Alaska, summaries of the three deployments covered under this project, and a brief description of the dataset and science directions pursued. Additionally, we provide information on lessons learned, publications, and presentations resulting from this work.

  6. Vocational Curriculum Modification. Teaching Technical Language to Learning Handicapped Students. Project HIRE: A Curriculum Management System for Instructing the Handicapped. Final Report, Volume 1.

    ERIC Educational Resources Information Center

    Gardner, David C.; And Others

    Volume 1 of the final report on Project HIRE reports the design, development, field-testing, and refining of self-instructional packages to teach entry level technical vocabulary to learning handicapped students mainstreamed in vocational programs. Volume 2, a management handbook, reports the methods and findings concerning development of…

  7. Joint Technical Architecture for Robotic Systems (JTARS)-Final Report

    NASA Technical Reports Server (NTRS)

    Bradley, Arthur T.; Holloway, Sidney E., III

    2006-01-01

    This document represents the final report for the Joint Technical Architecture for Robotic Systems (JTARS) project, funded by the Office of Exploration as part of the Intramural Call for Proposals of 2005. The project was prematurely terminated, without review, as part of an agency-wide realignment towards the development of a Crew Exploration Vehicle (CEV) and meeting the near-term goals of lunar exploration.

  8. Review of Final Year MSP Evaluations, Performance Period 2007. Analytic and Technical Support for Mathematics and Science Partnerships

    ERIC Educational Resources Information Center

    Bobronnikov, Ellen; Rhodes, Hilary; Bradley, Cay

    2010-01-01

    This final report culminates the evaluation and technical assistance provided for the U.S. Department of Education's Mathematics and Science Partnership (MSP) Program and its projects since 2005. As part of this support, Abt Associates looked across the portfolio of projects funded by the MSP program to draw lessons on best practices. This…

  9. Infrasound workshop for CTBT monitoring: Proceedings

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Christie, D.; Whitaker, R.

    1998-11-01

    It is expected that the establishment of new infrasound stations in the global IMS network by the Provisional Technical Secretariat of the CTBTO in Vienna will commence in the middle of 1998. Thus, decisions on the final operational design for IMS infrasound stations will have to be made within the next 12 months. Though many of the basic design problems have been resolved, it is clear that further work needs to be carried out during the coming year to ensure that IMS infrasound stations will operate with maximum capability in accord with the specifications determined during the May 1997 PrepCommore » Meeting. Some of the papers presented at the Workshop suggest that it may be difficult to design a four-element infrasound array station that will reliably detect and locate infrasound signals at all frequencies in the specified range from 0.02 to 4.0 Hz in all noise environments. Hence, if the basic design of an infrasound array is restricted to four array elements, the final optimized design may be suited only to the detection and location of signals in a more limited pass-band. Several participants have also noted that the reliable discrimination of infrasound signals could be quite difficult if the detection system leads to signal distortion. Thus, it has been emphasized that the detection system should not, if possible, compromise signal fidelity. This report contains the workshop agenda, a list of participants, and abstracts and viewgraphs from each presentation.« less

  10. Pacific Educational Computer Network Study. Final Report.

    ERIC Educational Resources Information Center

    Hawaii Univ., Honolulu. ALOHA System.

    The Pacific Educational Computer Network Feasibility Study examined technical and non-technical aspects of the formation of an international Pacific Area computer network for higher education. The technical study covered the assessment of the feasibility of a packet-switched satellite and radio ground distribution network for data transmission…

  11. Sensing systems efficiency evaluation and comparison for homeland security and homeland defense

    NASA Astrophysics Data System (ADS)

    Pakhomov, Alexander A.

    2010-04-01

    Designers and consumers of various security, intelligence, surveillance and reconnaissance (ISR) systems as well as various unattended ground sensors pay most attention to their commonly used performance characteristics such as probability of a target detection and probability of a false alarm. These characteristics are used for systems comparison and evaluation. However, it is not enough for end-users of these systems as well as for their total/final effectiveness assessment. This article presents and discusses a system approach to an efficiency estimation of the security and ISR systems. Presented approach aims at final result of the system's function and use. It allows setting up reasonable technical and structural requirements for the security and ISR systems, to make trustworthy comparison and practical application planning of such systems. It also allows finding forward-looking, perspective ways of systems development. Presented results can be guidance to both designers and consumers.

  12. Potential clinical impact of advanced imaging and computer-aided diagnosis in chest radiology: importance of radiologist's role and successful observer study.

    PubMed

    Li, Feng

    2015-07-01

    This review paper is based on our research experience in the past 30 years. The importance of radiologists' role is discussed in the development or evaluation of new medical images and of computer-aided detection (CAD) schemes in chest radiology. The four main topics include (1) introducing what diseases can be included in a research database for different imaging techniques or CAD systems and what imaging database can be built by radiologists, (2) understanding how radiologists' subjective judgment can be combined with technical objective features to improve CAD performance, (3) sharing our experience in the design of successful observer performance studies, and (4) finally, discussing whether the new images and CAD systems can improve radiologists' diagnostic ability in chest radiology. In conclusion, advanced imaging techniques and detection/classification of CAD systems have a potential clinical impact on improvement of radiologists' diagnostic ability, for both the detection and the differential diagnosis of various lung diseases, in chest radiology.

  13. Computational sciences in the upstream oil and gas industry

    PubMed Central

    Halsey, Thomas C.

    2016-01-01

    The predominant technical challenge of the upstream oil and gas industry has always been the fundamental uncertainty of the subsurface from which it produces hydrocarbon fluids. The subsurface can be detected remotely by, for example, seismic waves, or it can be penetrated and studied in the extremely limited vicinity of wells. Inevitably, a great deal of uncertainty remains. Computational sciences have been a key avenue to reduce and manage this uncertainty. In this review, we discuss at a relatively non-technical level the current state of three applications of computational sciences in the industry. The first of these is seismic imaging, which is currently being revolutionized by the emergence of full wavefield inversion, enabled by algorithmic advances and petascale computing. The second is reservoir simulation, also being advanced through the use of modern highly parallel computing architectures. Finally, we comment on the role of data analytics in the upstream industry. This article is part of the themed issue ‘Energy and the subsurface’. PMID:27597785

  14. Characterizing extrasolar planets

    NASA Astrophysics Data System (ADS)

    Brown, Timothy M.

    Transiting extrasolar planets provide the best current opportunities for characterizing the physical properties of extrasolar planets. In this review, I first describe the geometry of planetary transits, and methods for detecting and refining the observations of such transits. I derive the methods by which transit light curves and radial velocity data can be analyzed to yield estimates of the planetary radius, mass, and orbital parameters. I also show how visible-light and infrared spectroscopy can be valuable tools for understanding the composition, temperature, and dynamics of the atmospheres of transiting planets. Finally, I relate the outcome of a participatory lecture-hall exercise relating to one term in the Drake equation, namely the lifetime of technical civilizations.

  15. The Blue Dot Workshop: Spectroscopic Search for Life on Extrasolar Planets

    NASA Technical Reports Server (NTRS)

    Des Marais, David J. (Editor)

    1997-01-01

    This workshop explored the key questions and challenges associated with detecting life on an extrasolar planet. The final product will be a NASA Conference Publication which includes the abstracts from 21 talks, summaries of key findings, and recommendations for future research. The workshop included sessions on three related topics: the biogeochemistry of biogenic gases in the atmosphere, the chemistry and spectroscopy of planetary atmospheres, and the remote sensing of planetary atmospheres and surfaces. With the observation that planetary formation is probably a common phenomenon, together with the advent of the technical capability to locate and describe extrasolar planets, this research area indeed has an exciting future.

  16. Final Technical Report for DE-SC0008149

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Buchanan, Kristen

    The major goal of this project is to study spin waves in magnetic thin films, especially how spin waves respond to external stimuli. This is expected to lead to new insight into dynamic processes and new ideas for methods to control spin waves. Experimental studies are being done primarily using time- and spatially-resolved Brillouin light scattering (BLS) measurements on extended and patterned magnetic thin films. BLS is a versatile tool that provides a non-invasive probe of spin dynamics with frequencies of ~1 GHz to well over 100 GHz, diffraction-limited spatial resolution, 250-ps temporal resolution, and it is sensitive enough tomore » detect thermal magnons.« less

  17. Community College Technical Mathematics Project. Final Report.

    ERIC Educational Resources Information Center

    Self, Samuel L.

    The purpose of the research project was to develop an applied or technical mathematics curriculum which would meet the needs of vocational-technical students at the community college level. The research project was divided into three distinct phases: Identifying the mathematical concepts requisite for job-entry competencies in each of the…

  18. 7 CFR 614.10 - Appeals before the Farm Service Agency county committee.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... section are completed, provide the FSA county committee with a written technical determination in the form... part 780, a participant may appeal a final technical determination or a program decision to the FSA... appeal requests review of the technical determination by the applicable State Conservationist prior to...

  19. 77 FR 47495 - Final Priority; Technical Assistance on State Data Collection, Analysis, and Reporting-National...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-08

    ... intervention and preschool service providers with data on their qualifications, certification, and preparation... Priority; Technical Assistance on State Data Collection, Analysis, and Reporting--National IDEA Technical Assistance Center on Early Childhood Longitudinal Data Systems; Rule #0;#0;Federal Register / Vol. 77, No...

  20. 77 FR 18716 - Transportation Security Administration Postal Zip Code Change; Technical Amendment

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-28

    ... organizational changes and it has no substantive effect on the public. DATES: Effective March 28, 2012. FOR... No. 1572-9] Transportation Security Administration Postal Zip Code Change; Technical Amendment AGENCY: Transportation Security Administration, DHS. ACTION: Final rule. SUMMARY: This rule is a technical change to...

  1. Studying the Cost and Value of Library Services: Final Report. Technical Report APLAB/94-3/1,2,3,4.

    ERIC Educational Resources Information Center

    Kantor, Paul B.; And Others

    This is the final technical report (in three parts) of a 15-month long project to study the costs and value of library functions at five major research libraries. Twenty-one services or service aspects were studied, and numerous measures of the importance or benefit of the service to the users were made. These measures were studied together to lay…

  2. An Inquiry into Testing of Information Retrieval Systems. Comparative Systems Laboratory Final Technical Report, Part III: CSL Related Studies.

    ERIC Educational Resources Information Center

    Zull, Carolyn Gifford, Ed.; And Others

    This third volume of the Comparative Systems Laboratory (CSL) Final Technical Report is a collection of relatively independent studies performed on CSL materials. Covered in this document are studies on: (1) properties of files, including a study of the growth rate of a dictionary of index terms as influenced by number of documents in the file and…

  3. Programs of Study as a State Policy Mandate: A Longitudinal Study of the South Carolina Personal Pathways to Success Initiative. Unabridged Final Technical Report (Years 1-5)

    ERIC Educational Resources Information Center

    Hammond, Cathy; Withington, Cairen; Sharp, Julia L.; Mobley, Catherine; Drew, Sam F.; Stringfield, Samuel C.; Stipanovic, Natalie; Swiger, Caroline M.; Daugherty, Lindsay; Griffith, Cathy

    2014-01-01

    This final report presents findings from data collection and analysis conducted during a five-year study by the National Dropout Prevention Center (NDPC) at Clemson University, in conjunction with colleagues from the National Research Center for Career and Technical Education (NRCCTE) at the University of Louisville. This project was one of three…

  4. Ground-Based Radiometric Measurements of Slant Path Attenuation in the V/W Bands

    DTIC Science & Technology

    2016-04-01

    GROUND-BASED RADIOMETRIC MEASUREMENTS OF SLANT PATH ATTENUATION IN THE V/W BANDS APRIL 2016 FINAL TECHNICAL REPORT APPROVED FOR PUBLIC RELEASE...2. REPORT TYPE FINAL TECHNICAL REPORT 3. DATES COVERED (From - To) OCT 2012 – SEP 2015 4. TITLE AND SUBTITLE GROUND-BASED RADIOMETRIC MEASUREMENTS ...SUPPLEMENTARY NOTES 14. ABSTRACT Ground-based radiometric techniques were applied to measure the slant path attenuation cumulative distribution function to

  5. Final Technical Progress Report: Development of Low-Cost Suspension Heliostat; December 7, 2011 - December 6, 2012

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bender, W.

    2013-01-01

    Final technical progress report of SunShot Incubator Solaflect Energy. The project succeeded in demonstrating that the Solaflect Suspension Heliostat design is viable for large-scale CSP installations. Canting accuracy is acceptable and is continually improving as Solaflect improves its understanding of this design. Cost reduction initiatives were successful, and there are still many opportunities for further development and further cost reduction.

  6. Advanced Transportation System Studies Technical Area 2 (TA-2) Heavy Lift Launch Vehicle Development Contract. Volume 2; Technical Results

    NASA Technical Reports Server (NTRS)

    1995-01-01

    The purpose of the Advanced Transportation System Studies (ATSS) Technical Area 2 (TA-2) Heavy Lift Launch Vehicle Development contract was to provide advanced launch vehicle concept definition and analysis to assist NASA in the identification of future launch vehicle requirements. Contracted analysis activities included vehicle sizing and performance analysis, subsystem concept definition, propulsion subsystem definition (foreign and domestic), ground operations and facilities analysis, and life cycle cost estimation. This document is Volume 2 of the final report for the contract. It provides documentation of selected technical results from various TA-2 analysis activities, including a detailed narrative description of the SSTO concept assessment results, a user's guide for the associated SSTO sizing tools, an SSTO turnaround assessment report, an executive summary of the ground operations assessments performed during the first year of the contract, a configuration-independent vehicle health management system requirements report, a copy of all major TA-2 contract presentations, a copy of the FLO launch vehicle final report, and references to Pratt & Whitney's TA-2 sponsored final reports regarding the identification of Russian main propulsion technologies.

  7. Technical Evaluation Motor No. 7 (TEM-7)

    NASA Technical Reports Server (NTRS)

    Hughes, Phil

    1991-01-01

    The Technical Evaluation Motor No. 7 (TEM-7) test was a full-scale, full duration static test firing of a high performance motor-configuration solid rocket motor with nozzle vectoring. The final test report documents the procedures, performance, and results of the static test firing of TEM-7. All observations, discussions, conclusions, and recommendations included in the report are complete and final except for the TEM-7 fixed housing unbond investigation. A presentation and discussion of TEM-7 performance, anomalies, and test result concurrence with the objectives outlined in CTP-0107, Rev A, Space Shuttle Technical Evaluation Motor No. 7 (TEM-7) Static Fire Test Plan are included.

  8. Building Stronger State Energy Partnerships with the U.S. Department of Energy

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Marks, Kate

    2011-09-30

    This final technical report details the results of total work efforts and progress made from October 2007 – September 2011 under the National Association of State Energy Officials (NASEO) cooperative agreement DE-FC26-07NT43264, Building Stronger State Energy Partnerships with the U.S. Department of Energy. Major topical project areas in this final report include work efforts in the following areas: Energy Assurance and Critical Infrastructure, State and Regional Technical Assistance, Regional Initiative, Regional Coordination and Technical Assistance, and International Activities in China. All required deliverables have been provided to the National Energy Technology Laboratory and DOE program officials.

  9. Final Technical Report of Project DE-FG02-96ER14647

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lundeen, Stephen R.

    This is the final technical report of work completed under DOE support over the period Sept. 1, 1996 until May 31, 2015. The title of the project was "Ion/Excited Atom Collision Studies with a Rydberg Target and a CO2 Laser" from 9/1/96 to 10/31/06, and "Properties of Actinide Ions from Measurements of Rydberg Ion Fine Structure" from 11/1/06 until 5/31/15. The primary technical results were a detailed experimental study of resonant charge transfer between Rydberg atoms and highly-charged ions, and unique measurements of many properties of multiply-charged Thorium ions.

  10. 78 FR 34392 - Guidance for Industry and Food and Drug Administration Staff: Technical Considerations for Pen...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-07

    ...] Guidance for Industry and Food and Drug Administration Staff: Technical Considerations for Pen, Jet, and... availability of a final guidance document entitled ``Technical Considerations for Pen, Jet, and Related... developing information to support a marketing application for a pen, jet, or related injector device intended...

  11. Florida Study of Career and Technical Education. Final Report

    ERIC Educational Resources Information Center

    Jacobson, Louis; Mokher, Christine

    2014-01-01

    A key goal of the "Carl D. Perkins Career and Technical Education Act of 2006" ("Perkins IV") is to ensure career and technical education (CTE) programs are widely available for preparing high school and college students for "high skill, high wage, or high demand occupations in current or emerging professions"…

  12. Final Technical Report for Award DESC0011912, "Trimodal Tapping Mode Atomic Force Microscopy: Simultaneous 4D Mapping of Conservative and Dissipative Probe-Sample Interactions of Energy-Relevant Materials”

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Solares, Santiago D.

    The final project report covering the period 7/1/14-6/30/17 provides an overview of the technical accomplishments in the areas of (i) fundamental viscoelasticity, (ii) multifrequency atomic force microscopy, and (iii) characterization of energy-relevant materials with atomic force microscopy. A list of publications supported by the project is also provided.

  13. Application of Knowledge-Based Techniques to Tracking Function

    DTIC Science & Technology

    2006-09-01

    38394041 42434445 46474849 505152 53545556 57585960 616263 646566 676869 707172 737475 7677 7879 8081 8283 8485 8687 8889 9091 9293 9495 969798 99100...Knowledge-based applications to adaptive space-time processing. Volume I: Summary”, AFRL-SN-TR-2001-146 Vol. I (of Vol. VI ), Final Technical Report, July...2001-146 Vol. IV (of Vol. VI ), Final Technical Report, July 2001. [53] C. Morgan, L. Moyer, “Knowledge-based applications to adaptive space-time

  14. Forecasting the Future Food Service World of Work. Final Report. Volume III. Technical Papers on the Future of the Food Service Industry. Service Management Reports.

    ERIC Educational Resources Information Center

    Powers, Thomas F., Ed.; Swinton, John R., Ed.

    This third and final volume of a study on the future of the food service industry contains the technical papers on which the information in the previous two volumes was based. The papers were written by various members of the Pennsylvania State University departments of economics, food science, nutrition, social psychology, and engineering and by…

  15. Final Technical Report for contract number DE-FG02-05ER15670

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Glazebrook, Jane

    This is the final technical report for contract number DE-FG02-05ER15670. The project is now complete, and results of the project have been published. Two papers were published based on work done in the last three-year funding period. The DOIs of these papers are included below. The abstracts of the papers, providing summaries of the work, are included in the body of the report.

  16. Astrobee Periodic Technical Review (PTR) Delta 3

    NASA Technical Reports Server (NTRS)

    Provencher, Christopher; Smith, Marion F.; Smith, Ernest Everett; Bualat, Maria Gabriele; Barlow, Jonathan Spencer

    2017-01-01

    Astrobee is a free flying robot for the inside of the International Space Station (ISS). The Periodic Technical Review (PTR) delta 3 is the final design review of the system presented to stakeholders.

  17. Polar source analysis : technical memorandum

    DOT National Transportation Integrated Search

    2017-09-29

    The following technical memorandum describes the development, testing and analysis of various polar source data sets. The memorandum also includes recommendation for potential inclusion in future releases of AEDT. This memorandum is the final deliver...

  18. 2005 v4.2 Technical Support Document

    EPA Pesticide Factsheets

    Technical Support Document for the Final Transport Rule describes how updated 2005 NEI, version 2 emissions and were processed for air quality modeling in support of the Cross-state Air Pollution Rule (CSAPR).

  19. Direct Final Rule for Technical Amendments for Marine Spark-Ignition Engines and Vessels

    EPA Pesticide Factsheets

    Rule published September 16, 2010 to make technical amendments to the design standard for portable marine fuel tanks. This rule incorporates safe recommended practices, developed through industry consensus.

  20. Research on the EDM Technology for Micro-holes at Complex Spatial Locations

    NASA Astrophysics Data System (ADS)

    Y Liu, J.; Guo, J. M.; Sun, D. J.; Cai, Y. H.; Ding, L. T.; Jiang, H.

    2017-12-01

    For the demands on machining micro-holes at complex spatial location, several key technical problems are conquered such as micro-Electron Discharge Machining (micro-EDM) power supply system’s development, the host structure’s design and machining process technical. Through developing low-voltage power supply circuit, high-voltage circuit, micro and precision machining circuit and clearance detection system, the narrow pulse and high frequency six-axis EDM machining power supply system is developed to meet the demands on micro-hole discharging machining. With the method of combining the CAD structure design, CAE simulation analysis, modal test, ODS (Operational Deflection Shapes) test and theoretical analysis, the host construction and key axes of the machine tool are optimized to meet the position demands of the micro-holes. Through developing the special deionized water filtration system to make sure that the machining process is stable enough. To verify the machining equipment and processing technical developed in this paper through developing the micro-hole’s processing flow and test on the real machine tool. As shown in the final test results: the efficient micro-EDM machining pulse power supply system, machine tool host system, deionized filtration system and processing method developed in this paper meet the demands on machining micro-holes at complex spatial locations.

  1. Blurred digital mammography images: an analysis of technical recall and observer detection performance.

    PubMed

    Ma, Wang Kei; Borgen, Rita; Kelly, Judith; Millington, Sara; Hilton, Beverley; Aspin, Rob; Lança, Carla; Hogg, Peter

    2017-03-01

    Blurred images in full-field digital mammography are a problem in the UK Breast Screening Programme. Technical recalls may be due to blurring not being seen on lower resolution monitors used for review. This study assesses the visual detection of blurring on a 2.3-MP monitor and a 5-MP report grade monitor and proposes an observer standard for the visual detection of blurring on a 5-MP reporting grade monitor. 28 observers assessed 120 images for blurring; 20 images had no blurring present, whereas 100 images had blurring imposed through mathematical simulation at 0.2, 0.4, 0.6, 0.8 and 1.0 mm levels of motion. Technical recall rate for both monitors and angular size at each level of motion were calculated. χ 2 tests were used to test whether significant differences in blurring detection existed between 2.3- and 5-MP monitors. The technical recall rate for 2.3- and 5-MP monitors are 20.3% and 9.1%, respectively. The angular size for 0.2- to 1-mm motion varied from 55 to 275 arc s. The minimum amount of motion for visual detection of blurring in this study is 0.4 mm. For 0.2-mm simulated motion, there was no significant difference [χ 2 (1, N = 1095) = 1.61, p = 0.20] in blurring detection between the 2.3- and 5-MP monitors. According to this study, monitors ≤2.3 MP are not suitable for technical review of full-field digital mammography images for the detection of blur. Advances in knowledge: This research proposes the first observer standard for the visual detection of blurring.

  2. Blurred digital mammography images: an analysis of technical recall and observer detection performance

    PubMed Central

    Borgen, Rita; Kelly, Judith; Millington, Sara; Hilton, Beverley; Aspin, Rob; Lança, Carla; Hogg, Peter

    2017-01-01

    Objective: Blurred images in full-field digital mammography are a problem in the UK Breast Screening Programme. Technical recalls may be due to blurring not being seen on lower resolution monitors used for review. This study assesses the visual detection of blurring on a 2.3-MP monitor and a 5-MP report grade monitor and proposes an observer standard for the visual detection of blurring on a 5-MP reporting grade monitor. Methods: 28 observers assessed 120 images for blurring; 20 images had no blurring present, whereas 100 images had blurring imposed through mathematical simulation at 0.2, 0.4, 0.6, 0.8 and 1.0 mm levels of motion. Technical recall rate for both monitors and angular size at each level of motion were calculated. χ2 tests were used to test whether significant differences in blurring detection existed between 2.3- and 5-MP monitors. Results: The technical recall rate for 2.3- and 5-MP monitors are 20.3% and 9.1%, respectively. The angular size for 0.2- to 1-mm motion varied from 55 to 275 arc s. The minimum amount of motion for visual detection of blurring in this study is 0.4 mm. For 0.2-mm simulated motion, there was no significant difference [χ2 (1, N = 1095) = 1.61, p = 0.20] in blurring detection between the 2.3- and 5-MP monitors. Conclusion: According to this study, monitors ≤2.3 MP are not suitable for technical review of full-field digital mammography images for the detection of blur. Advances in knowledge: This research proposes the first observer standard for the visual detection of blurring. PMID:28134567

  3. Seattle To Portland Inter-City ITS Corridor Study And Communications Plan, Final Report

    DOT National Transportation Integrated Search

    1996-03-01

    THIS DOCUMENT IS THE FINAL REPORT PRESENTING THE SEATTLE TO PORTLAND INTELLIGENT TRANSPORTATION SYSTEM (ITS) EARLY DEPLOYMENT PLAN. THE FINAL REPORT SYNTHESIZES INFORMATION FROM TECHNICAL MEMORANDUMS 1 THROUGH 5; INCLUDING EXISTING AND FUTURE CONDITI...

  4. Benchmark Analysis of Career and Technical Education in Lenawee County. Final Report.

    ERIC Educational Resources Information Center

    Hollenbeck, Kevin

    The career and technical education (CTE) provided in grades K-12 in the county's vocational-technical center and 12 local public school districts of Lenawee County, Michigan, was benchmarked with respect to its attention to career development. Data were collected from the following sources: structured interviews with a number of key respondents…

  5. Transesophageal echocardiography and intracardiac echocardiography differently predict potential technical challenges or failures of interatrial shunts catheter-based closure.

    PubMed

    Rigatelli, Gianluca; Rigateli, Gianluca; Cardaioli, Paolo; Braggion, Gabriele; Aggio, Silvio; Giordan, Massimo; Magro, Beatrice; Nascimben, Alberto; Favaro, Alberto; Roncon, Loris; Rincon, Loris

    2007-02-01

    We sought to prospectively assess the role of transesophageal (TEE) and intracardiac echocardiography (ICE) in detecting potential technical difficulties or failures in patients submitted to interatrial shunts percutaneous closure. We prospectively enrolled 46 consecutive patients (mean age 35+/-28, 8 years, 30 female) referred to our center for catheter-based closure of interatrial shunts. All patients were screened with TEE before the intervention. Patients who met the inclusion criteria underwent ICE study before the closure attempt (40 patients). TEE detected potential technical difficulties in 22.5% (9/40) patients, whereas ICE detected technical difficulties in 32.5% (13/40 patients). In patients with positive TEE/ICE the procedural success (92.4% versus 100% and, P = ns) and follow-up failure rate (7.7% versus 0%, P = ns) were similar to patients with negative TEE/ICE, whereas the fluoroscopy time (7 +/- 1.2 versus 5 +/- 0.7 minutes, P < 0.03), the procedural time (41 +/- 4.1 versus 30 +/- 8.2 minutes, P +/- 0.03), and technical difficulties rate (23.1% versus 0%, P = 0.013) were higher. Differences between ICE and TEE in the evaluation of rims, measurement of ASD or fossa ovalis, and detection of venous valve and embryonic septal membrane remnants impacted on technical challenges and on procedural and fluoroscopy times but did not influence the success rate and follow-up failure rate.

  6. International Project on Technical and Vocational Education (UNEVOC). International Advisory Committee (Third Session, Paris, France, October 2-4, 1995). Final Report = Projet International pour l'Enseignement Technique et Professionnel (UNEVOC). Comite Consultatif International (Troisieme Session, Paris, France, 2-4 octobre 1995). Rapport Final.

    ERIC Educational Resources Information Center

    United Nations Educational, Scientific, and Cultural Organization, Paris (France).

    The international advisory committee of the International Project on Technical and Vocational Education (UNEVOC) held its third session in Paris in October 1995. Advisory committee members and observers from the United Nations' specialized, intergovernmental, and nongovernmental organizations reviewed the major UNEVOC project activities undertaken…

  7. International Project on Technical and Vocational Education (UNEVOC). International Advisory Committee (Second Session, Paris, France, December 12-14, 1994). Final Report = Projet International pour l'Enseignement Technique et Professionnel (UNEVOC). Comite Consultatif International (Deuxieme Session, Paris, France, 12-14 decembre 1994). Rapport Final.

    ERIC Educational Resources Information Center

    United Nations Educational, Scientific, and Cultural Organization, Paris (France).

    The international advisory committee of the International Project on Technical and Vocational Education (UNEVOC) held its second session in Paris in December 1994. Nine advisory committee members and observers from the United Nations' specialized, intergovernmental, and nongovernmental organizations reviewed the major UNEVOC project activities…

  8. Final Technical Report for ARRA Funding

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Rusack, Roger; Mans, Jeremiah; Poling, Ronald

    Final technical report of the University of Minnesota experimental high energy physics group for ARRA support. The Cryogenic Dark Matter Experiment (CDMS) used the funds received to construct a new passive shield to protect a high-purity germanium detector located in the Soudan mine in Northern Minnesota from cosmic rays. The BESIII and the CMS groups purchased computing hardware to assemble computer farms for data analysis and to generate large volumes of simulated data for comparison with the data collected.

  9. Making a Difference in the Lives of Infants and Toddlers and Their Families: The Impacts of Early Head Start. Volumes I-III: Final Technical Report [and] Appendixes [and] Local Contributions to Understanding the Programs and Their Impacts.

    ERIC Educational Resources Information Center

    Love, John M.; Kisker, Ellen Eliason; Ross, Christine M.; Schochet, Peter Z.; Brooks-Gunn, Jeanne; Paulsell, Diane; Boller, Kimberly; Constantine, Jill; Vogel, Cheri; Fuligni, Alison Sidle; Brady-Smith, Christy

    Early Head Start was designed in 1994 as a 2-generation program to enhance children's development and health, strengthen family and community partnerships, and support the staff delivering new services to low-income families with pregnant women, infants, or toddlers. This document contains the final technical report, appendixes, and local…

  10. International Project on Technical and Vocational Education (UNEVOC). International Advisory Committee (First Session, Berlin, Germany, September 20-22, 1993). Final Report = Projet International pour l'Enseignement Technique et Professionnel (UNEVOC). Comite Consultatif International (Premiere Session, Berlin, Germany, 20-22 septembre 1993). Rapport Final.

    ERIC Educational Resources Information Center

    United Nations Educational, Scientific, and Cultural Organization, Paris (France).

    The international advisory committee of the International Project on Technical and Vocational Education (UNEVOC) held its first session in Berlin in September 1993. The advisory committee's 10 members and observers from the United Nations' specialized, intergovernmental, and nongovernmental organizations discussed educational policy, links between…

  11. Airborne Laser Remote Sensor for Oil Detection and Classification : Engineering Requirements and Technical Considerations Relevant to a Performance Specification

    DOT National Transportation Integrated Search

    1975-08-01

    This report outlines the engineering requirements for an Airborne Laser Remote Sensor for Oil Detection and Classification System. Detailed engineering requirements are given for the major units of the system. Technical considerations pertinent to a ...

  12. Illinois Clean Coal Institute 2005 annual report. Final technical report for the period September 1st, 2004, through August 31, 2005 on projects funded by the Illinois Department of Commerce and Economic Opportunity

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    NONE

    2005-11-08

    This final technical report contains the abstracts and executive summaries of projects funded through the Illinois Clean Coal Institute solicitation entitled 'Request for proposals No. 04-1(ICCI/RFP04-1)'. Support of these projects is by the Office of Coal Development and Department of Commerce and Economic Opportunity. The projects fall into the following categories: advanced coal mining technologies; coal preparation and coal production business practice; management of coal combustion byproducts; commercialization and technology transfer. Final project extensions are also recorded.

  13. Grid Stability Awareness System (GSAS) Final Scientific/Technical Report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Feuerborn, Scott; Ma, Jian; Black, Clifton

    The project team developed a software suite named Grid Stability Awareness System (GSAS) for power system near real-time stability monitoring and analysis based on synchrophasor measurement. The software suite consists of five analytical tools: an oscillation monitoring tool, a voltage stability monitoring tool, a transient instability monitoring tool, an angle difference monitoring tool, and an event detection tool. These tools have been integrated into one framework to provide power grid operators with both real-time or near real-time stability status of a power grid and historical information about system stability status. These tools are being considered for real-time use in themore » operation environment.« less

  14. Study on the key alignment technology of the catadioptric optical system

    NASA Astrophysics Data System (ADS)

    Song, Chong; Fu, Xing; Fu, Xi-hong; Kang, Xiao-peng; Liu, Kai

    2017-02-01

    Optical system alignment has a great influence on the whole system accuracy. In this paper, the processing of optical system alignment was mainly studied, the processing method of optics on the primary and secondary mirrors, front correction lens group and behind correction lens group with high precision centering lathe and internal focusing telescope. Then using the height indicator complete the system alignment of the primary mirror, secondary mirror, front correction group and behind correction group. Finally, based on the zygo interferometer detect the wavefront information. Using this alignment program for catadioptric optical system, the wavefront aberration of optical system, focal length, modulation transfer function (MTF) and other technical indicators have reached the requirements.

  15. Renewable Fuel Standard (RFS2): Final Rule Additional Resources

    EPA Pesticide Factsheets

    The final rule of fuels and fuel additives: renewable fuel standard program is published on March 26, 2010 and is effective on July 1, 2010. You will find the links to this final rule and technical amendments supporting this rule.

  16. 75 FR 48273 - Technical Service Provider Assistance

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-10

    ... DEPARTMENT OF AGRICULTURE Natural Resources Conservation Service 7 CFR Part 652 RIN 0578-AA48 Technical Service Provider Assistance AGENCY: Natural Resources Conservation Service, United States Department of Agriculture. ACTION: Final rule; Correcting amendment. SUMMARY: The Natural Resources...

  17. Partial Withdrawal and Final Rule for Nonroad Technical Amendments

    EPA Pesticide Factsheets

    Amendments to the technical hardship provisions under the Transition Program for Equipment Manufacturers related to the Tier 4 standards for nonroad diesel engines, and to the replacement engine exemption generally applicable to new nonroad engines.

  18. Wolffian duct derivative anomalies: technical considerations when encountered during robot-assisted radical prostatectomy.

    PubMed

    Acharya, Sujeet S; Gundeti, Mohan S; Zagaja, Gregory P; Shalhav, Arieh L; Zorn, Kevin C

    2009-04-01

    Although malformations of the genitourinary tract are typically identified during childhood, they can remain silent until incidental detection in evaluation and treatment of other pathologies during adulthood. The advent of the minimally invasive era in urologic surgery has given rise to unique challenges in the surgical management of anomalies of the genitourinary tract. This article reviews the embryology of anomalies of Wolffian duct (WD) derivatives with specific attention to the seminal vesicles, vas deferens, ureter, and kidneys. This is followed by a discussion of the history of the laparoscopic approach to WD derivative anomalies. Finally, we present two cases to describe technical considerations when managing these anomalies when encountered during robotic-assisted radical prostatectomy. The University of Chicago Robotic Laparoscopic Radical Prostatectomy (RLRP) database was reviewed for cases where anomalies of WD derivatives were encountered. We describe how modifications in technique allowed for completion of the procedure without difficulty. None Of the 1230 RLRP procedures performed at our institution by three surgeons, only two cases (0.16%) have been noted to have a WD anomaly. These cases were able to be completed without difficulty by making simple modifications in technique. Although uncommon, it is important for the urologist to be familiar with the origin and surgical management of WD anomalies, particularly when detected incidentally during surgery. Simple modifications in technique allow for completion of RLRP without difficulty.

  19. RAS testing in metastatic colorectal cancer: advances in Europe.

    PubMed

    Van Krieken, J Han J M; Rouleau, Etienne; Ligtenberg, Marjolijn J L; Normanno, Nicola; Patterson, Scott D; Jung, Andreas

    2016-04-01

    Personalized medicine shows promise for maximizing efficacy and minimizing toxicity of anti-cancer treatment. KRAS exon 2 mutations are predictive of resistance to epidermal growth factor receptor-directed monoclonal antibodies in patients with metastatic colorectal cancer. Recent studies have shown that broader RAS testing (KRAS and NRAS) is needed to select patients for treatment. While Sanger sequencing is still used, approaches based on various methodologies are available. Few CE-approved kits, however, detect the full spectrum of RAS mutations. More recently, "next-generation" sequencing has been developed for research use, including parallel semiconductor sequencing and reversible termination. These techniques have high technical sensitivities for detecting mutations, although the ideal threshold is currently unknown. Finally, liquid biopsy has the potential to become an additional tool to assess tumor-derived DNA. For accurate and timely RAS testing, appropriate sampling and prompt delivery of material is critical. Processes to ensure efficient turnaround from sample request to RAS evaluation must be implemented so that patients receive the most appropriate treatment. Given the variety of methodologies, external quality assurance programs are important to ensure a high standard of RAS testing. Here, we review technical and practical aspects of RAS testing for pathologists working with metastatic colorectal cancer tumor samples. The extension of markers from KRAS to RAS testing is the new paradigm for biomarker testing in colorectal cancer.

  20. The Technical and Biological Reproducibility of Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry (MALDI-TOF MS) Based Typing: Employment of Bioinformatics in a Multicenter Study.

    PubMed

    Oberle, Michael; Wohlwend, Nadia; Jonas, Daniel; Maurer, Florian P; Jost, Geraldine; Tschudin-Sutter, Sarah; Vranckx, Katleen; Egli, Adrian

    2016-01-01

    The technical, biological, and inter-center reproducibility of matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI TOF MS) typing data has not yet been explored. The aim of this study is to compare typing data from multiple centers employing bioinformatics using bacterial strains from two past outbreaks and non-related strains. Participants received twelve extended spectrum betalactamase-producing E. coli isolates and followed the same standard operating procedure (SOP) including a full-protein extraction protocol. All laboratories provided visually read spectra via flexAnalysis (Bruker, Germany). Raw data from each laboratory allowed calculating the technical and biological reproducibility between centers using BioNumerics (Applied Maths NV, Belgium). Technical and biological reproducibility ranged between 96.8-99.4% and 47.6-94.4%, respectively. The inter-center reproducibility showed a comparable clustering among identical isolates. Principal component analysis indicated a higher tendency to cluster within the same center. Therefore, we used a discriminant analysis, which completely separated the clusters. Next, we defined a reference center and performed a statistical analysis to identify specific peaks to identify the outbreak clusters. Finally, we used a classifier algorithm and a linear support vector machine on the determined peaks as classifier. A validation showed that within the set of the reference center, the identification of the cluster was 100% correct with a large contrast between the score with the correct cluster and the next best scoring cluster. Based on the sufficient technical and biological reproducibility of MALDI-TOF MS based spectra, detection of specific clusters is possible from spectra obtained from different centers. However, we believe that a shared SOP and a bioinformatics approach are required to make the analysis robust and reliable.

  1. Assay techniques for detection of exposure to sulfur mustard, cholinesterase inhibitors, sarin, soman, GF, and cyanide. Technical bulletin

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    NONE

    1996-05-01

    This technical bulletin provides analytical techniques to identify toxic chemical agents in urine or blood samples. It is intended to provide the clinician with laboratory tests to detect exposure to sulfur mustard, cholinesterase inhibitors, sarin, soman, GF, and cyanide.

  2. A Pilot Program to Provide Ownership Skills to Seniors in the Vocational Technical Schools and Other Educational Institutions, Year Two. Final Report.

    ERIC Educational Resources Information Center

    Norwich Regional Vocational Technical School, CT.

    Responding to a Small Business Administration statement that technical school graduates lack knowledge of business principles, the Norwich (Connecticut) Regional Vocational Technical School conducted a course in small business ownership/management for all of its seniors. The required course, a fifty-four-hour module, replaced one English,…

  3. A Case Study of Technical Assistance to Demonstration Programs for Young Handicapped Children. Part III.

    ERIC Educational Resources Information Center

    Behr, Shirley K.; And Others

    The report describes the third and final year of a 3-year case study of the technical assistance process as implemented by the Technical Assistance Development System (TADS) for the staffs of two demonstration programs for preschool handicapped children and their families. Following a review of TADS and the two demonstration programs, the…

  4. Chemical Durability Improvement and Static Fatigue of Glasses.

    DTIC Science & Technology

    1982-08-01

    Afl-Alla 837 RENSSELAER POLYIECmfJ!C INST TRtOY NY DEPT OF MATERIAL--ETC F/6 ii/ CHEMICAL DURABILITY IMPROVEMENT AND STATIC FATIGUE OF GLASSESW AUC2...82 M TOMOZAWA NOGGIN 7A-C-0315 UNC LASS IF IED N ENEEEEEE FINAL TECHNICAL REPORT For the period April 1, 1978 "u March 31, 198200 CHEMICAL DURABILITY...REPORT A PERIOD COVERED Chemical Durability Improvement and Static Final Technical Report Fatiue o GlasesApril 1, 1978"’,March 31, 1982 S. PERFORMING ORG

  5. Experimental Program Final Technical Progress Report: 15 February 2007 to 30 September 2012

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kinney, Edward R.

    2014-09-12

    This is the final technical report of the grant DE-FG02-04ER41301 to the University of Colorado at Boulder entitled "Intermediate Energy Nuclear Physics" and describes the results of our funded activities during the period 15 February 2007 to 30 September 2012. These activities were primarily carried out at Fermilab, RHIC, and the German lab DESY. Significant advances in these experiments were carried out by members of the Colorado group and are described in detail.

  6. Final Technical Report - Center for Technology for Advanced Scientific Component Software (TASCS)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sussman, Alan

    2014-10-21

    This is a final technical report for the University of Maryland work in the SciDAC Center for Technology for Advanced Scientific Component Software (TASCS). The Maryland work focused on software tools for coupling parallel software components built using the Common Component Architecture (CCA) APIs. Those tools are based on the Maryland InterComm software framework that has been used in multiple computational science applications to build large-scale simulations of complex physical systems that employ multiple separately developed codes.

  7. Iowa Hill Pumped Storage Project Investigations - Final Technical Report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hanson, David

    2016-07-01

    This Final Technical Report is a summary of the activities and outcome of the Department of Energy (DOE) Assistance Agreement DE-EE0005414 with the Sacramento Municipal Utility District (SMUD). The Assistance Agreement was created in 2012 to support investigations into the Iowa Hill Pumped-storage Project (Project), a new development that would add an additional 400 MW of capacity to SMUD’s existing 688MW Upper American River Hydroelectric Project (UARP) in the Sierra Nevada mountains east of Sacramento, California.

  8. Renewable Fuel Standard Program (RFS1): Final Rule Additional Resources

    EPA Pesticide Factsheets

    The final rule of fuels and fuel additives: renewable fuel standard program is published on May 1, 2007 and is effective on September 1, 2007. You will find the links to this final rule and technical amendments supporting this rule.

  9. Assurance Penalty Level Analysis Final Rule TSD

    EPA Pesticide Factsheets

    This Technical Support Document (TSD) supports EPA’s determination that the final Transport Rule’s assurance provision penalty requirement provides sufficient deterrence against a state exceeding its assurance level.

  10. Final Rule for Technical Amendments to the Highway and Nonroad Diesel Regulations

    EPA Pesticide Factsheets

    This action corrects errors and omissions from the previous rules, makes minor changes to the regulations to assist entities with regulatory compliance, and makes technical amendments that resulted from discussions with various diesel stakeholders.

  11. Final priority. Rehabilitation Training: Job-Driven Vocational Rehabilitation Technical Assistance Center. Final priority.

    PubMed

    2014-08-19

    The Assistant Secretary for Special Education and Rehabilitative Services announces a priority under the Rehabilitation Training program to establish a Job-Driven Vocational Rehabilitation Technical Assistance Center (JDVRTAC). The Assistant Secretary may use this priority for competitions in fiscal year (FY) 2014 and later years. We take this action to focus on training in an area of national need. Specifically, this priority responds to the Presidential Memorandum to Federal agencies directing them to take action to address job-driven training for the Nation's workers. The JDVRTAC will provide technical assistance (TA) to State vocational rehabilitation (VR) agencies to help them develop for individuals with disabilities training and employment opportunities that meet the needs of today's employers.

  12. National Security Science and Technology Initiative: Air Cargo Screening, Final Report for CRADA Number NFE-07-01081

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bingham, Philip; Bush, John; Bowerman, Biays

    The non-intrusive inspection (NII) of consolidated air cargo carried on commercial passenger aircraft continues to be a technically challenging, high-priority requirement of the Department of Homeland Security’s Science and Technology Directorate (DHS S&T), the Transportation Security Agency and the Federal Aviation Administration. The goal of deploying a screening system that can reliably and cost-effectively detect explosive threats in consolidated cargo without adversely affecting the flow of commerce will require significant technical advances that will take years to develop. To address this critical National Security need, the Battelle Memorial Institute (Battelle), under a Cooperative Research and Development Agreement (CRADA) with fourmore » of its associated US Department of Energy (DOE) National Laboratories (Oak Ridge, Pacific Northwest, Idaho, and Brookhaven), conducted a research and development initiative focused on identifying, evaluating, and integrating technologies for screening consolidated air cargo for the presence of explosive threats. Battelle invested $8.5M of internal research and development funds during fiscal years 2007 through 2009.« less

  13. NASA's Pursuit of Low-Noise Propulsion for Low-Boom Commercial Supersonic Vehicles

    NASA Technical Reports Server (NTRS)

    Bridges, James; Brown, Clifford A.; Seidel, Jonathan A.

    2018-01-01

    Since 2006, when the Fundamental Aeronautics Program was instituted within NASA's Aeronautics Mission Directorate, there has been a Project looking at the technical barriers to commercial supersonic flight. Among the barriers is the noise produced by aircraft during landing and takeoff. Over the years that followed, research was carried out at NASA aeronautics research centers, often in collaboration with academia and industry, addressing the problem. In 2013, a high-level milestone was established, described as a Technical Challenge, with the objective of demonstrating the feasibility of a low-boom supersonic airliner that could meet current airport noise regulations. The Technical Challenge was formally called "Low Noise Propulsion for Low Boom Aircraft", and was completed in late 2016. This paper reports the technical findings from this Technical Challenge, reaching back almost 10 years to review the technologies and tools that were developed along the way. It also discusses the final aircraft configuration and propulsion systems required for a supersonic civilian aircraft to meet noise regulations using the technologies available today. Finally, the paper documents the model-scale tests that validated the acoustic performance of the study aircraft.

  14. NASA's Pursuit of Low-Noise Propulsion for Low-Boom Commercial Supersonic Vehicles

    NASA Technical Reports Server (NTRS)

    Bridges, James; Brown, Clifford A.; Seidel, Jonathan

    2018-01-01

    Since 2006, when the Fundamental Aeronautics Program was instituted within NASA's Aeronautics Mission Directorate, there has been a Project looking at the technical barriers to commercial supersonic flight. Among the barriers is the noise produced by aircraft during landing and takeoff. Over the years that followed, research was carried out at NASA aeronautics research centers, often in collaboration with academia and industry, addressing the problem. In 2013, a high-level milestone was established, described as a Technical Challenge, with the objective of demonstrating the feasibility of a low-boom supersonic airliner that could meet current airport noise regulations. The Technical Challenge was formally called a Low Noise Propulsion for Low Boom Aircraft and was completed in late 2016. This paper reports the technical findings from this Technical Challenge, reaching back almost 10 years to review the technologies and tools that were developed along the way. It also discusses the final aircraft configuration and propulsion systems required for a supersonic civilian aircraft to meet noise regulations using the technologies available today. Finally, the paper documents the model-scale tests that validated the acoustic performance of the study aircraft.

  15. Final Revisions Rule State Budgets and New Unit Set-Asides TSD

    EPA Pesticide Factsheets

    This technical support document shows the underlying data and calculations used to quantify the state budget revisions and new unit set-aside revisions made in the final revisions rule, as well as those revisions included in the direct final revisions rule

  16. Lunar Prospector: First Results and Lessons Learned

    NASA Astrophysics Data System (ADS)

    Scott Hubbard, G.; Feldman, William; Cox, Sylvia A.; Smith, Marcie A.; Chu-Thielbar, Lisa

    2002-01-01

    Lunar Prospector, the first competitively selected mission in NASA's Discovery Program, is conducting a one-year orbital survey of the Moon's composition and structure. Launched on January 6 1998, the suite of five instruments is measuring water/ice to a sensitivity of 50 ppm (hydrogen), detecting key elemental constituents, gas release events and mapping the Moon's gravitational and magnetic fields. The mission is described with emphasis on the first scientific results and lessons learned from managing a very low cost project. A mission overview and systems description is given along with final mission trajectories. Lessons learned from government-industry teaming, new modes of project management, and novel contractual arrangements are discussed. The suite of five instruments (neutron spectrometer, alpha particle spectrometer, gamma-ray spectrometer, electron reflectometer and magnetometer) is outlined with attention to final technical performance as well as development on a constrained budget and schedule. A review of our novel approaches to education and public outreach is discussed and a summary with suggestions and implications for future missions is provided.

  17. 77 FR 37284 - Technical Amendments

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-21

    ... DEPARTMENT OF LABOR Office of Workers' Compensation Programs 20 CFR Parts 701, 702, 703, 725, and 726 RIN 1240-AA05 Technical Amendments AGENCY: Office of Workers' Compensation Programs, Labor. ACTION: Final rule. SUMMARY: The Office of Workers' Compensation Programs is making [[Page 37285

  18. Vehicle infrastructure integration proof of concept : technical description--vehicle : final report

    DOT National Transportation Integrated Search

    2009-05-19

    This report provides the technical description of the VII system developed for the Cooperative Agreement VII Program between the USDOT and the VII Consortium. The basic architectural elements are summarized and detailed descriptions of the hardware a...

  19. Research on detecting heterogeneous fibre from cotton based on linear CCD camera

    NASA Astrophysics Data System (ADS)

    Zhang, Xian-bin; Cao, Bing; Zhang, Xin-peng; Shi, Wei

    2009-07-01

    The heterogeneous fibre in cotton make a great impact on production of cotton textile, it will have a bad effect on the quality of product, thereby affect economic benefits and market competitive ability of corporation. So the detecting and eliminating of heterogeneous fibre is particular important to improve machining technics of cotton, advance the quality of cotton textile and reduce production cost. There are favorable market value and future development for this technology. An optical detecting system obtains the widespread application. In this system, we use a linear CCD camera to scan the running cotton, then the video signals are put into computer and processed according to the difference of grayscale, if there is heterogeneous fibre in cotton, the computer will send an order to drive the gas nozzle to eliminate the heterogeneous fibre. In the paper, we adopt monochrome LED array as the new detecting light source, it's lamp flicker, stability of luminous intensity, lumens depreciation and useful life are all superior to fluorescence light. We analyse the reflection spectrum of cotton and various heterogeneous fibre first, then select appropriate frequency of the light source, we finally adopt violet LED array as the new detecting light source. The whole hardware structure and software design are introduced in this paper.

  20. NetView technical research

    NASA Technical Reports Server (NTRS)

    1993-01-01

    This is the Final Technical Report for the NetView Technical Research task. This report is prepared in accordance with Contract Data Requirements List (CDRL) item A002. NetView assistance was provided and details are presented under the following headings: NetView Management Systems (NMS) project tasks; WBAFB IBM 3090; WPAFB AMDAHL; WPAFB IBM 3084; Hill AFB; McClellan AFB AMDAHL; McClellan AFB IBM 3090; and Warner-Robins AFB.

  1. Inventory of greenhouse gas emissions from on-road vehicles in Midwestern USA States and integrated approach to achieving environmental sustainability in transportation : USDOT Region V Regional University Transportation Center final report : technical su

    DOT National Transportation Integrated Search

    2016-12-29

    Two project objectives one technical and one educational- were laid out in this project. The technical objective was to assess current inventory of greenhouse gases (GHG) in the six Midwestern states of the nation and to estimate improvements as ...

  2. Emissions Inventory Final Rule TSD

    EPA Pesticide Factsheets

    This technical support document (TSD) provides the details of emissions data processing done in support of EPA's final rulemaking effort for the Federal Transport Rule, now known as the Cross-State Air Pollution Rule.

  3. The simulation study on optical target laser active detection performance

    NASA Astrophysics Data System (ADS)

    Li, Ying-chun; Hou, Zhao-fei; Fan, Youchen

    2014-12-01

    According to the working principle of laser active detection system, the paper establishes the optical target laser active detection simulation system, carry out the simulation study on the detection process and detection performance of the system. For instance, the performance model such as the laser emitting, the laser propagation in the atmosphere, the reflection of optical target, the receiver detection system, the signal processing and recognition. We focus on the analysis and modeling the relationship between the laser emitting angle and defocus amount and "cat eye" effect echo laser in the reflection of optical target. Further, in the paper some performance index such as operating range, SNR and the probability of the system have been simulated. The parameters including laser emitting parameters, the reflection of the optical target and the laser propagation in the atmosphere which make a great influence on the performance of the optical target laser active detection system. Finally, using the object-oriented software design methods, the laser active detection system with the opening type, complete function and operating platform, realizes the process simulation that the detection system detect and recognize the optical target, complete the performance simulation of each subsystem, and generate the data report and the graph. It can make the laser active detection system performance models more intuitive because of the visible simulation process. The simulation data obtained from the system provide a reference to adjust the structure of the system parameters. And it provides theoretical and technical support for the top level design of the optical target laser active detection system and performance index optimization.

  4. Transportation Network Data Requirements for Assessing Criticality for Resiliency and Adaptation Planning

    DOT National Transportation Integrated Search

    2017-11-01

    This report is one of two NCST Research Report documents produced as part of a project to advance the technical modeling tools for resiliency and adaptation planning, especially those used for criticality rankings. The official final technical report...

  5. Comment Deadlines Established Regarding the LightSquared Technical Working Group Report

    DOT National Transportation Integrated Search

    2011-06-30

    On June 30, 2011, LightSquared Subsidiary LLC (LightSquared) submitted a final report of the : technical working group co-chaired by LightSquared and the United States Global Positioning System : (GPS) Industry Council (USGIC)1 and organized in respo...

  6. Technical report on prototype intelligent network flow optimization (INFLO) dynamic speed harmonization and queue warning.

    DOT National Transportation Integrated Search

    2015-06-01

    This Technical Report on Prototype Intelligent Network Flow Optimization (INFLO) Dynamic Speed Harmonization and Queue Warning is the final report for the project. It describes the prototyping, acceptance testing and small-scale demonstration of the ...

  7. NUSC Technical Publications Guide.

    DTIC Science & Technology

    1985-05-01

    Facility personnel especially that of A. Castelluzzo, E. Deland, J. Gesel , and E. Szlosek (all of Code 4343). Reviewed and Approved: 14 July 1980 D...their technical content and format. Review and approve the manual outline, the review manuscript, and the final camera - reproducible copy. Conduct in

  8. Cross-State Air Pollution Rule Update Allowance Allocation Final Rule TSD

    EPA Pesticide Factsheets

    This Technical Support Document (TSD) provides information that supports EPA’s determination of unit-level allocations for existing and new units under the final Cross-State Air Pollution Rule Update.

  9. Guidelines for producing training films and videos.

    PubMed

    Harper, P B

    1991-01-01

    Drawing from experience in producing a film on the surgical procedure of female sterilization, 4 guidelines to technical film production for training purposes are presented and discussed in this paper. In order of presentation in the text, the paper 1st encourages identifying and securing a technical expert, then clearly identifying steps of the technical procedure, involving trainees and trainers in the production process, and working with experienced producers, scriptwriters, and crew members. Returning to the 1st guideline, the technical advisor will have a central presence during all photography and editing, and ideally should not have any personal investment in the procedure being shown. Prior to script finalization and sorting, research is urged to ensure concrete procedural steps. Printed materials, slides, interviews of experienced clinicians, procedure observation, and test videotape shooting may be called upon and employed as parts of the research phase. Trainees should participate during preliminary research, script development, and pretesting of early film versions, their suggestions for change incorporated where appropriate in the final version. On the final point of securing experienced workers, country nationals sensitive to relevant cultural and background dynamics should be included in the team. The special concerns of airport security regulation and customs requirements knowledge are essential, as well as their attention to assuring adequate on-site electricity for camera equipment.

  10. Northeast Corridor Improvement Project Electrification - New Haven, CT to Boston, MA : Final Environmental Statement/Report : v. 2. Technical Studies

    DOT National Transportation Integrated Search

    1994-10-31

    This document is the final environmental impact statement and final environmental impact report (FEIS/R) on the proposal by the National Railroad Passenger Corporation (Amtrak) to complete the electrification of the Northeast Corridor main line by ex...

  11. Health care fraud and abuse data collection program: technical revisions to Healthcare Integrity and Protection Data Bank data collection activities. Final rule.

    PubMed

    2004-09-21

    The rule finalizes technical changes to the Healthcare Integrity and Protection Data Bank (HIPDB) data collection reporting requirements by clarifying the types of personal numeric identifiers that may be reported to the data bank in connection with adverse actions. The rule clarifies that in lieu of a Social Security Number (SSN), an individual taxpayer identification number (ITIN) may be reported to the data bank when, in those limited situations, an individual does not have an SSN.

  12. Recovery Act-SmartGrid regional demonstration transmission and distribution (T&D) Infrastructure

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hedges, Edward T.

    This document represents the Final Technical Report for the Kansas City Power & Light Company (KCP&L) Green Impact Zone SmartGrid Demonstration Project (SGDP). The KCP&L project is partially funded by Department of Energy (DOE) Regional Smart Grid Demonstration Project cooperative agreement DE-OE0000221 in the Transmission and Distribution Infrastructure application area. This Final Technical Report summarizes the KCP&L SGDP as of April 30, 2015 and includes summaries of the project design, implementation, operations, and analysis performed as of that date.

  13. Final Technical Report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sobecky, Patricia A; Taillefert, Martial

    This final technical report describes results and findings from a research project to examine the role of microbial phosphohydrolase enzymes in naturally occurring subsurface microorganisms for the purpose of promoting the immobilization of the radionuclide uranium through the production of insoluble uranium phosphate minerals. The research project investigated the microbial mechanisms and the physical and chemical processes promoting uranium biomineralization and sequestration in oxygenated subsurface soils. Uranium biomineralization under aerobic conditions can provide a secondary biobarrier strategy to immobilize radionuclides should the metal precipitates formed by microbial dissimilatory mechanisms remobilize due to a change in redox state.

  14. Waveguide Studies for Fiber Optics and Optical Signal Processing Applications.

    DTIC Science & Technology

    1980-04-01

    AO-A086 115 UNI!VERtSIT? OF SOUTIUR CALEPCRNA LOS AMUSS / 5 WAVGUIDE STUIES15 FOR FEB53 OpTECS AND OpTICAL SEOSA.o P /0Ksu-y "/6 UNLSIIDAPR N0 E...SAMUE Flola-??-c-sa UNCASZFIORAC-M-8042 U Final Technical Report (1 1April 1950 L V ~ WAVEGUIDE STUDIES FOR FIBER OPTICS AND OPTICAL SIGNAL PROCESSING...and Subtitle) 081 6&4𔃾JODO )EI YAVECUIDESTUDIES FOR JIBER OPTICS ANDL 7 Final ,T/echnical epoErt, OPTICAL SI’tNAL PROCESSING APPLICATIONS.4 11 Se 77

  15. SELECTIVE DISSEMINATION OF INFORMATION (SDI). VOLUME I, PILOT TEST AT U.S. ARMY NATICK LABORATORIES. FINAL REPORT. ARMY TECHNICAL LIBRARY IMPROVEMENT STUDIES (ATLIS), REPORT NO. 15.

    ERIC Educational Resources Information Center

    BIVONA, WILLIAM A.

    THIS VOLUME PRESENTS THE RESULTS OF A NINE-MONTH TEST OF A PROTOTYPE SELECTIVE DISSEMINATION OF INFORMATION (SDI) SYSTEM DEVELOPED FOR THE ARMY TECHNICAL LIBRARIES. DURING THE PILOT TEST ONE THOUSAND DOCUMENTS WERE CATALOGED, INDEXED, AND DISSEMINATED TO TWENTY-FIVE SCIENTIFIC AND TECHNICAL PERSONNEL. MATCHING OF THE INTEREST PROFILES OF THESE…

  16. Ceramic High Efficiency Particulate Air (HEPA) Filter Final Report CRADA No. TC02160.0

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mitchell, M.; Bergman, W.

    2017-08-25

    The technical objective of this project was to develop a ceramic HEPA filter technology, by initially producing and testing coupon ceramics, small scale prototypes, and full scale prototype HEPA filters, and to address relevant manufacturing and commercialization technical issues.

  17. 7 CFR 614.6 - Agency records and decision notices.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... notifies participants of the agency's preliminary and final technical determinations and program decisions... decision notice within 10 working days of rendering a technical determination or program decision. In lieu of certified mail, NRCS may hand deliver notices to participants with written acknowledgment of...

  18. ECOS E-MATRIX Methane and Volatile Organic Carbon (VOC) Emissions Best Practices Database

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Parisien, Lia

    2016-01-31

    This final scientific/technical report on the ECOS e-MATRIX Methane and Volatile Organic Carbon (VOC) Emissions Best Practices Database provides a disclaimer and acknowledgement, table of contents, executive summary, description of project activities, and briefing/technical presentation link.

  19. 77 FR 18914 - National Motor Vehicle Title Information System (NMVTIS): Technical Corrections

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-29

    ... 1121-AA79 National Motor Vehicle Title Information System (NMVTIS): Technical Corrections AGENCY... (OJP) is promulgating this direct final rule for its National Motor Vehicle Title Information System... INFORMATION CONTACT paragraph. II. Background The National Motor Vehicle Title Information System was...

  20. Intelligent transportation system (ITS) study for the Buffalo and Niagara Falls metropolitan area, Erie and Niagara Counties, New York : final report, technical summary

    DOT National Transportation Integrated Search

    1997-06-18

    This document provides a technical summary for the seven working papers prepared for the New York State Department of Transportation (NYSDOT) Buffalo and Niagara Falls Intelligent Transportation System (ITS) Study.

  1. 77 FR 8095 - Technical Corrections to Commission Regulations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-14

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission 18 CFR Part 2 [Docket No. RM11-30-000; Order No. 756] Technical Corrections to Commission Regulations Issued February 8, 2012. AGENCY: Federal Energy Regulatory Commission, DOE. ACTION: Final rule: correcting amendment. SUMMARY: This document adds...

  2. 78 FR 13543 - Defense Federal Acquisition Regulation Supplement; Technical Amendments

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-28

    ... DEPARTMENT OF DEFENSE Defense Acquisition Regulations System 48 CFR Parts 201, 204, 215, 225, 227, 242, 245, and 252 Defense Federal Acquisition Regulation Supplement; Technical Amendments AGENCY: Defense Acquisition Regulations System, Department of Defense (DoD). ACTION: Final rule. SUMMARY: DoD is...

  3. Technical Insights into Highly Sensitive Isolation and Molecular Characterization of Fixed and Live Circulating Tumor Cells for Early Detection of Tumor Invasion.

    PubMed

    Laget, Sophie; Broncy, Lucile; Hormigos, Katia; Dhingra, Dalia M; BenMohamed, Fatima; Capiod, Thierry; Osteras, Magne; Farinelli, Laurent; Jackson, Stephen; Paterlini-Bréchot, Patrizia

    2017-01-01

    Circulating Tumor Cells (CTC) and Circulating Tumor Microemboli (CTM) are Circulating Rare Cells (CRC) which herald tumor invasion and are expected to provide an opportunity to improve the management of cancer patients. An unsolved technical issue in the CTC field is how to obtain highly sensitive and unbiased collection of these fragile and heterogeneous cells, in both live and fixed form, for their molecular study when they are extremely rare, particularly at the beginning of the invasion process. We report on a new protocol to enrich from blood live CTC using ISET® (Isolation by SizE of Tumor/Trophoblastic Cells), an open system originally developed for marker-independent isolation of fixed tumor cells. We have assessed the impact of our new enrichment method on live tumor cells antigen expression, cytoskeleton structure, cell viability and ability to expand in culture. We have also explored the ISET® in vitro performance to collect intact fixed and live cancer cells by using spiking analyses with extremely low number of fluorescent cultured cells. We describe results consistently showing the feasibility of isolating fixed and live tumor cells with a Lower Limit of Detection (LLOD) of one cancer cell per 10 mL of blood and a sensitivity at LLOD ranging from 83 to 100%. This very high sensitivity threshold can be maintained when plasma is collected before tumor cells isolation. Finally, we have performed a comparative next generation sequencing (NGS) analysis of tumor cells before and after isolation from blood and culture. We established the feasibility of NGS analysis of single live and fixed tumor cells enriched from blood by our system. This study provides new protocols for detection and characterization of CTC collected from blood at the very early steps of tumor invasion.

  4. Estimating abundance

    USGS Publications Warehouse

    Sutherland, Chris; Royle, Andy

    2016-01-01

    This chapter provides a non-technical overview of ‘closed population capture–recapture’ models, a class of well-established models that are widely applied in ecology, such as removal sampling, covariate models, and distance sampling. These methods are regularly adopted for studies of reptiles, in order to estimate abundance from counts of marked individuals while accounting for imperfect detection. Thus, the chapter describes some classic closed population models for estimating abundance, with considerations for some recent extensions that provide a spatial context for the estimation of abundance, and therefore density. Finally, the chapter suggests some software for use in data analysis, such as the Windows-based program MARK, and provides an example of estimating abundance and density of reptiles using an artificial cover object survey of Slow Worms (Anguis fragilis).

  5. Estimating abundance: Chapter 27

    USGS Publications Warehouse

    Royle, J. Andrew

    2016-01-01

    This chapter provides a non-technical overview of ‘closed population capture–recapture’ models, a class of well-established models that are widely applied in ecology, such as removal sampling, covariate models, and distance sampling. These methods are regularly adopted for studies of reptiles, in order to estimate abundance from counts of marked individuals while accounting for imperfect detection. Thus, the chapter describes some classic closed population models for estimating abundance, with considerations for some recent extensions that provide a spatial context for the estimation of abundance, and therefore density. Finally, the chapter suggests some software for use in data analysis, such as the Windows-based program MARK, and provides an example of estimating abundance and density of reptiles using an artificial cover object survey of Slow Worms (Anguis fragilis).

  6. Performance calculation and simulation system of high energy laser weapon

    NASA Astrophysics Data System (ADS)

    Wang, Pei; Liu, Min; Su, Yu; Zhang, Ke

    2014-12-01

    High energy laser weapons are ready for some of today's most challenging military applications. Based on the analysis of the main tactical/technical index and combating process of high energy laser weapon, a performance calculation and simulation system of high energy laser weapon was established. Firstly, the index decomposition and workflow of high energy laser weapon was proposed. The entire system was composed of six parts, including classical target, platform of laser weapon, detect sensor, tracking and pointing control, laser atmosphere propagation and damage assessment module. Then, the index calculation modules were designed. Finally, anti-missile interception simulation was performed. The system can provide reference and basis for the analysis and evaluation of high energy laser weapon efficiency.

  7. Technical aspects and limitations of fractional flow reserve measurement.

    PubMed

    Jerabek, Stepan; Kovarnik, Tomas

    2018-02-27

    The only indication for coronary revascularization is elimination of ischaemia. Invasive hemodynamic methods (fractional flow reserve - FFR and instantaneous wave-free ratio (iFR) are superior to coronary angiography in detection of lesions causing myocardial ischaemia. Current European guidelines for myocardial revascularization recommend using of FFR for detection of functional assessment of lesions severity in category IA and number of these procedures increases. However, routine usage of these methods requires knowledge of technical requirements and limitations. The aim of the study is to summarise good clinical practice for FFR and iFR measurements with explanation of possible technical challenges, that are necessary for increasing of measurement accuracy. Authors describe frequent technical mistakes and malpractice during invasive assessment of lesion severity in coronary arteries.

  8. Comparative biochemistry and physiology of iron-respiring bacteria from acidic and neutral-pH environments: Final Technical Report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Magnuson, T S

    2009-04-07

    Acidophilic dissimilatory iron-reducing bacteria (DIRB) are now being detected in a variety of ‘extreme’ low-pH, radionuclide- and heavy-metal contaminated habitats where Fe(III) reduction is taking place, and may represent a significant proportion of metal-transforming organisms in these environments. Acidiphilium cryptum is our model organism, a facultative iron-respiring Alphaproteobacterium. Major findings of this project have been 1) Discovery of novel outer-membrane and periplasmic cytochromes c in acidophiles that are reactive with Fe and Cr, 2) Discovery of Cr(VI) reduction mechanisms in acidophiles, mediated by c-type cytochromes and other reductase activity, 3) Development of enzyme detection methods specific for Cr-reducing enzymes, 4)more » Characterization of biofilm formation in A. cryptum, and 5) Annotation of the Acidiphilium cryptum genome (Magnuson, Kusel, and Cummings, DOE-JGI 2005-2006). Two manuscripts and one book chapter have been published, and several more mauscripts are prepared for submission.« less

  9. Missing data and technical variability in single-cell RNA-sequencing experiments.

    PubMed

    Hicks, Stephanie C; Townes, F William; Teng, Mingxiang; Irizarry, Rafael A

    2017-11-06

    Until recently, high-throughput gene expression technology, such as RNA-Sequencing (RNA-seq) required hundreds of thousands of cells to produce reliable measurements. Recent technical advances permit genome-wide gene expression measurement at the single-cell level. Single-cell RNA-Seq (scRNA-seq) is the most widely used and numerous publications are based on data produced with this technology. However, RNA-seq and scRNA-seq data are markedly different. In particular, unlike RNA-seq, the majority of reported expression levels in scRNA-seq are zeros, which could be either biologically-driven, genes not expressing RNA at the time of measurement, or technically-driven, genes expressing RNA, but not at a sufficient level to be detected by sequencing technology. Another difference is that the proportion of genes reporting the expression level to be zero varies substantially across single cells compared to RNA-seq samples. However, it remains unclear to what extent this cell-to-cell variation is being driven by technical rather than biological variation. Furthermore, while systematic errors, including batch effects, have been widely reported as a major challenge in high-throughput technologies, these issues have received minimal attention in published studies based on scRNA-seq technology. Here, we use an assessment experiment to examine data from published studies and demonstrate that systematic errors can explain a substantial percentage of observed cell-to-cell expression variability. Specifically, we present evidence that some of these reported zeros are driven by technical variation by demonstrating that scRNA-seq produces more zeros than expected and that this bias is greater for lower expressed genes. In addition, this missing data problem is exacerbated by the fact that this technical variation varies cell-to-cell. Then, we show how this technical cell-to-cell variability can be confused with novel biological results. Finally, we demonstrate and discuss how batch-effects and confounded experiments can intensify the problem. © The Author 2017. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  10. Alternatives for Jet Engine Control. Volume 1: Modelling and Control Design with Jet Engine Data

    NASA Technical Reports Server (NTRS)

    Sain, M. K.

    1985-01-01

    This document compiles a comprehensive list of publications supported by, or related to, National Aeronautics and Space Administration Grant NSG-3048, entitled "Alternatives for Jet Engine Control". Dr. Kurt Seldner was the original Technical Officer for the grant, at Lewis Research Center. Dr. Bruce Lehtinen was the final Technical Officer. At the University of Notre Dame, Drs. Michael K. Sain and R. Jeffrey Leake were the original Project Directors, with Dr. Sain becoming the final Project Director. Publications cover work over a ten-year period. The Final Report is divided into two parts. Volume i, "Modelling and Control Design with Jet Engine Data", follows in this report. Volume 2, "Modelling and Control Design with Tensors", has been bound separately.

  11. 32 CFR 2001.51 - Technical security.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Surveillance Countermeasures and TEMPEST necessary to detect or deter exploitation of classified information..., TEMPEST Countermeasures for Facilities, and SPB Issuance 6-97, National Policy on Technical Surveillance...

  12. 32 CFR 2001.51 - Technical security.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Surveillance Countermeasures and TEMPEST necessary to detect or deter exploitation of classified information..., TEMPEST Countermeasures for Facilities, and SPB Issuance 6-97, National Policy on Technical Surveillance...

  13. 32 CFR 2001.51 - Technical security.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Surveillance Countermeasures and TEMPEST necessary to detect or deter exploitation of classified information..., TEMPEST Countermeasures for Facilities, and SPB Issuance 6-97, National Policy on Technical Surveillance...

  14. 32 CFR 2001.51 - Technical security.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Surveillance Countermeasures and TEMPEST necessary to detect or deter exploitation of classified information..., TEMPEST Countermeasures for Facilities, and SPB Issuance 6-97, National Policy on Technical Surveillance...

  15. 32 CFR 2001.51 - Technical security.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Surveillance Countermeasures and TEMPEST necessary to detect or deter exploitation of classified information..., TEMPEST Countermeasures for Facilities, and SPB Issuance 6-97, National Policy on Technical Surveillance...

  16. First results of ground-based LWIR hyperspectral imaging remote gas detection

    NASA Astrophysics Data System (ADS)

    Zheng, Wei-jian; Lei, Zheng-gang; Yu, Chun-chao; Wang, Hai-yang; Fu, Yan-peng; Liao, Ning-fang; Su, Jun-hong

    2014-11-01

    The new progress of ground-based long-wave infrared remote sensing is presented. The LWIR hyperspectral imaging by using the windowing spatial and temporal modulation Fourier spectroscopy, and the results of outdoor ether gas detection, verify the features of LWIR hyperspectral imaging remote sensing and technical approach. It provides a new technical means for ground-based gas remote sensing.

  17. 48 CFR 252.235-7011 - Final scientific or technical report.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... technical report. 252.235-7011 Section 252.235-7011 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CLAUSES AND FORMS SOLICITATION PROVISIONS AND CONTRACT... of the report; and (c) For submission of reports in other than paper copy, contact the Defense...

  18. 48 CFR 252.235-7011 - Final scientific or technical report.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... technical report. 252.235-7011 Section 252.235-7011 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CLAUSES AND FORMS SOLICITATION PROVISIONS AND CONTRACT... of the report; and (c) For submission of reports in other than paper copy, contact the Defense...

  19. 48 CFR 252.235-7011 - Final scientific or technical report.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... technical report. 252.235-7011 Section 252.235-7011 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CLAUSES AND FORMS SOLICITATION PROVISIONS AND CONTRACT... of the report; and (c) For submission of reports in other than paper copy, contact the Defense...

  20. 48 CFR 252.235-7011 - Final scientific or technical report.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... technical report. 252.235-7011 Section 252.235-7011 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CLAUSES AND FORMS SOLICITATION PROVISIONS AND CONTRACT... of the report; and (c) For submission of reports in other than paper copy, contact the Defense...

  1. 48 CFR 252.235-7011 - Final scientific or technical report.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... technical report. 252.235-7011 Section 252.235-7011 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CLAUSES AND FORMS SOLICITATION PROVISIONS AND CONTRACT... of the report; and (c) For submission of reports in other than paper copy, contact the Defense...

  2. Vocational Outreach Involving Community Exchange (VOICE). Final Report.

    ERIC Educational Resources Information Center

    Huckabee, Johnni

    A Jonesboro, Arkansas project was designed and implemented to increase the awareness of vocational education, increase community support and involvement in vocational education, and establish improved communication in the vocational-technical education field. Interaction between the vocational-technical school and the local school community was a…

  3. Technical Challenges for a Comprehensive Test Ban: A historical perspective to frame the future (Invited)

    NASA Astrophysics Data System (ADS)

    Wallace, T. C.

    2013-12-01

    In the summer of 1958 scientists from the Soviet block and the US allies met in Geneva to discuss what it would take to monitor a forerunner to a Comprehensive Test Ban Treaty at the 'Conference of Experts to Study the Possibility of Detecting Violations of a Possible Agreement on Suspension of Nuclear Tests'. Although armed with a limited resume of observations, the conference recommended a multi-phenomenology approach (air sampling, acoustics, seismic and electromagnetic) deployed it a network of 170 sites scattered across the Northern Hemisphere, and hypothesized a detection threshold of 1kt for atmospheric tests and 5kt for underground explosions. The conference recommendations spurred vigorous debate, with strong disagreement with the stated detection hypothesis. Nevertheless, the technical challenges posed lead to a very focused effort to improve facilities, methodologies and, most importantly, research and development on event detection, location and identification. In the ensuing 50 years the various challenges arose and were eventually 'solved'; these included quantifying yield determination to enter a Limited Threshold Test Ban, monitoring broad areas of emerging nuclear nations, and after the mid-1990s lowering the global detection threshold to sub-kiloton levels for underground tests. Today there is both an international monitoring regime (ie, the International Monitoring System, or IMS) and a group of countries that have their own national technical means (NTM). The challenges for the international regime are evolving; the IMS has established itself as a very credible monitoring system, but the demand of a CTBT to detect and identify a 'nuclear test' of diminished size (zero yield) poses new technical hurdles. These include signal processing and understanding limits of resolution, location accuracy, integration of heterogeneous data, and accurately characterizing anomalous events. It is possible to extrapolate past technical advances to predict what should be available by 2020; detection of coupled explosions to 100s of tons for all continental areas, as well as a probabilistic assessment of event identification.

  4. King County Metro Transit Hybrid Articulated Buses: Final Evaluation Results

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Chandler, K.; Walkowicz, K.

    2006-12-01

    Final technical report compares and evaluates new diesel and diesel hybrid-electric articulated buses operated as part of the King County Metro Transit (KC Metro) fleet in Seattle, Washington. The evaluation lasted 12 months.

  5. 78 FR 1143 - Explosive Siting Requirements; Correction

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-08

    ... launch site operators in site planning for the storage and handling of energetic liquids and explosives...: For technical questions concerning this final rule, contact Yvonne Tran, Commercial Space... this final rule, contact Laura Montgomery, AGC 200, [[Page 1144

  6. Final June Revisions Rule State Budgets and New Unit Set-Asides TSD

    EPA Pesticide Factsheets

    This technical support document (TSD) for the final revisions to the Transport Rule shows the underlying data and calculations used to quantify the state budget revisions and new unit set-aside revisions.

  7. Department of Defense Access to Intellectual Property for Weapon Systems Sustainment

    DTIC Science & Technology

    2017-05-01

    and acquiring technical data rights …  The cost benefit analysis of including a priced contract option for the future delivery of technical data...entail in terms of cost and benefits , while one of the activities to be finalized is the contract-specific technical data elements.66...Virginia 22311-1882 May 2017 Approved for public release; distribution is unlimited. IDA Paper P-8266 Log: H 17-000030 About This Publication This

  8. 10 CFR 51.92 - Supplement to the final environmental impact statement.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... changes in the proposed action that are relevant to environmental concerns; or (2) There are new and..., technical, and other benefits and costs of the proposed action, to the extent that the final environmental... costs; (5) Include an analysis of other energy alternatives, to the extent that the final environmental...

  9. Dissemination of Continuing Education Materials Via Television Delivery Systems. Final Technical Report and Final Report.

    ERIC Educational Resources Information Center

    Munushian, Jack

    In 1972, the University of Southern California School of Engineering established a 4-channel interactive instructional television network. It was designed to allow employees of participating industries to take regular university science and engineering courses and special continuing education courses at or near their work locations. Final progress…

  10. The role of non-technical skills in surgery

    PubMed Central

    Agha, Riaz A.; Fowler, Alexander J.; Sevdalis, Nick

    2015-01-01

    Non-technical skills are of increasing importance in surgery and surgical training. A traditional focus on technical skills acquisition and competence is no longer enough for the delivery of a modern, safe surgical practice. This review discusses the importance of non-technical skills and the values that underpin successful modern surgical practice. This narrative review used a number of sources including written and online, there was no specific search strategy of defined databases. Modern surgical practice requires; technical and non-technical skills, evidence-based practice, an emphasis on lifelong learning, monitoring of outcomes and a supportive institutional and health service framework. Finally these requirements need to be combined with a number of personal and professional values including integrity, professionalism and compassionate, patient-centred care. PMID:26904193

  11. 75 FR 16345 - Administrative Practices and Procedures; Good Guidance Practices; Technical Amendment

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-01

    .... FDA-1999-N-3539] (formerly Docket No. 1999N-4783) Administrative Practices and Procedures; Good Guidance Practices; Technical Amendment AGENCY: Food and Drug Administration, HHS. ACTION: Final rule... Subjects in 21 CFR Part 10 Administrative practice and procedure, News media. 0 Therefore, under the...

  12. Final report : for the period of December 1999 through November 30, 2000 : Florida Transit Training Program (1999/2000) : Florida Technical Assistance Program (1999/2000)

    DOT National Transportation Integrated Search

    2000-01-01

    The following progress report is intended to highlight the significant activities of the Florida Transit Training Program and Florida Technical Assistant Program. The following progress report is intended to highlight the significant activities of th...

  13. 78 FR 34264 - Technical Corrections to the HIPAA Privacy, Security, and Enforcement Rules

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-07

    ...-AA03 Technical Corrections to the HIPAA Privacy, Security, and Enforcement Rules AGENCY: Office for... corrections address certain inadvertent errors and omissions in the HIPAA Privacy, Security, and Enforcement... (HHS or ``the Department'') published a final rule to implement changes to the HIPAA Privacy, Security...

  14. 76 FR 11414 - Defense Federal Acquisition Regulation Supplement; Independent Research and Development Technical...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-02

    ... Acquisition Regulation Supplement; Independent Research and Development Technical Descriptions (DFARS Case... (DFARS) to require contractors to report independent research and development (IR&D) projects generating... the address shown below on or before May 2, 2011, to be considered in the formation of the final rule...

  15. Professional Personnel Evaluation System: 1983-84 Final Technical Report.

    ERIC Educational Resources Information Center

    Doss, David A.

    This technical report summarizes the evaluation ratings given to professionals on probation or up for contract renewal in the Austin Independent School District. Graphs, tables, and rankings are presented for each specified population: all district teachers combined; teachers by school level (elementary, junior high, senior high); teachers by…

  16. High School Graduation Minimum Competency Requirements. Final Technical Report.

    ERIC Educational Resources Information Center

    Austin Independent School District, TX. Office of Research and Evaluation.

    This technical report details the testing results and analyses supporting the evaluation findings related to the Austin (Texas) Independent School District (AISD) minimum competency graduation requirements. The graduation competency status of all AISD students in grades 8 to 12 are documented. The report provides additional information on the data…

  17. 76 FR 16531 - Technical Correction for Neurological Listing Cross-Reference

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-24

    ... 1-800-325-0778, or visit our Internet site, Social Security Online, at http://www.socialsecurity.gov... SOCIAL SECURITY ADMINISTRATION 20 CFR Part 404 [Docket No. SSA-2011-0019] RIN 0960-AH33 Technical Correction for Neurological Listing Cross-Reference AGENCY: Social Security Administration. ACTION: Final...

  18. Improving Vocational Education in Post-High School Institutions. Final Report.

    ERIC Educational Resources Information Center

    MacArthur, Earl W.

    Four ongoing programs in postsecondary vocational-technical education were examined in a national institute attended by 59 representatives from 31 states. Institutions reporting programs were: (1) Los Angeles Trade and Technical College, California, (2) Washtenaw Community College, Ann Arbor, Michigan, (3) Rockingham Community College, Wentworth,…

  19. Chicago Manufacturing Tech Prep. Fiscal Year 1991 Final Report.

    ERIC Educational Resources Information Center

    Chicago City Colleges, IL.

    During its first year of development in 1991, the Chicago Manufacturing Technical Preparation (Tech Prep) Program established a plan for implementing an industry-driven, articulated 4-year manufacturing technology course of study that integrates applied academic courses with technical courses and meets industry hiring standards. The project…

  20. 78 FR 29239 - Final Priority; Technical Assistance To Improve State Data Capacity-National Technical Assistance...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-20

    ... reporting requirements. Changes: None. Focus TA on Assessment and Discipline Data Comment: Three commenters agreed with the importance of focusing on assessment and discipline data, and two commenters agreed with... decisions and actions associated with data collection and reporting. One commenter stated that assessment...

  1. Modular Radioisotope Thermoelectric Generator (RTG) Program. Final technical report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    1992-12-31

    Section 2.0 of this report summarizes the MOD-RTG reference flight design, and Section 3.0 discusses the Ground Demonstration System design. Multicouple technology development is discussed in Section 4.0, and Section 5.0 lists all published technical papers prepared during the course of the contract.

  2. Methodology in Seeking Stakeholder Perceptions of Effective Technical Oral Presentations: An Exploratory Pilot Study

    ERIC Educational Resources Information Center

    Bhattacharyya, Ena; Patil, Arun; Sargunan, Rajeswary Appacutty

    2010-01-01

    Engineering communication studies indicate the importance of oral presentations as an indispensable component of workplace oral communication activities; however, since there is limited literature regarding stakeholder perceptions of effective presentation skills and attributes in technical oral presentations or final year engineering project…

  3. Additional Final Area Designations and Technical Amendment for the 2012 Annual Fine Particle Standard Established in 2012 - Mar 2015

    EPA Pesticide Factsheets

    EPA is establishing or revising initial area designations and a technical amendment to correct an inadvertent error in the initial designation for one area for the 2012 annual national ambient air quality standards for fine particle pollution.

  4. 75 FR 41404 - List of Approved Spent Fuel Storage Casks: NUHOMS®

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-16

    .... The NRC is taking this action because the applicant identified that a certain Technical Specification (TS) for Boral characterization was not written precisely. Specifically, the requirements for meeting... changes to the technical specifications. The NRC also published a direct final rule on May 6, 2010 (75 FR...

  5. Research in Automatic Russian-English Scientific and Technical Lexicography. Final Report.

    ERIC Educational Resources Information Center

    Wayne State Univ., Detroit, MI.

    Techniques of reversing English-Russian scientific and technical dictionaries into Russian-English versions through semi-automated compilation are described. Sections on manual and automatic processing discuss pre- and post-editing, the task program, updater (correction of errors and revision by specialist in a given field), the system employed…

  6. National Data Program for the Marine Environment Technical Development Plan. Final Report, Volume Two.

    ERIC Educational Resources Information Center

    System Development Corp., Santa Monica, CA.

    A national data program for the marine environment is recommended. Volume 2 includes: (1) objectives, scope, and methodology; (2) summary of the technical development plan; (3) agency development plans - Great Lakes and coastal development and (4) marine data network development plans. (Author)

  7. Course of Study Project. Final Report. Vocational-Technical Education Departmental Report, Vol. 17, No. 18.

    ERIC Educational Resources Information Center

    Pennsylvania State Univ., University Park. Div. of Occupational and Vocational Studies.

    Designed for use by area vocational-technical schools and other vocational programs, this project developed courses of study in eight occupational areas: commercial art, appliance repair, automotive mechanics, graphic arts, building trades maintenance, building construction trades, diesel mechanics, and welding. Course-of-study development…

  8. Seminar for Preparation of Professional Personnel for Vocational-Technical Education. Final Report.

    ERIC Educational Resources Information Center

    Dillon, Roy D.; Horner, James T.

    Seminar participants included college administrative officers, state vocational education directors, vocational-technical teacher educators, and Office of Education staff. The purpose of the June, 1968 seminar was to consider strategies for resolving critical vocational education personnel supply and demand problems. Presentations included in the…

  9. 75 FR 33167 - Technical Amendment Language Change From “Wholly” to “Fully”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-11

    ... SOCIAL SECURITY ADMINISTRATION 20 CFR Parts 404, 405, 408, 416, and 418 [Docket No. SSA-2009-0062] RIN 0960-AH16 Technical Amendment Language Change From ``Wholly'' to ``Fully'' AGENCY: Social Security... these final rules, call Brian J. Rudick, Office of Regulations, Social Security Administration, 6401...

  10. 76 FR 58144 - Defense Federal Acquisition Regulation Supplement; Presumption of Development Exclusively at...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-20

    ... technical data package, in cases where the Government may have funded only a small portion of the... subcontractor's asserted restrictions on technical data and computer software. DATES: Effective date: September... data and computer software. More specifically, the final rule affects these validation procedures in...

  11. 75 FR 49408 - Navigation and Navigable Waters; Technical, Organizational, and Conforming Amendments, Bridges

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-13

    ... Conforming Amendments, Bridges AGENCY: Coast Guard, DHS. ACTION: Final rule. SUMMARY: This rule makes non... technical corrections to Coast Guard bridge and navigable waters regulations. This rule will have no... announces or gathers public opinion or other information regarding bridge matters, nor will it change the...

  12. Research in network management techniques for tactical data communications networks

    NASA Astrophysics Data System (ADS)

    Boorstyn, R.; Kershenbaum, A.; Maglaris, B.; Sarachik, P.

    1982-09-01

    This is the final technical report for work performed on network management techniques for tactical data networks. It includes all technical papers that have been published during the control period. Research areas include Packet Network modelling, adaptive network routing, network design algorithms, network design techniques, and local area networks.

  13. A System for Evaluating Microcomputer Courseware for Vocational and Technical Education. Final Report.

    ERIC Educational Resources Information Center

    Chase, Shirley A.; And Others

    A project was conducted to design a system for evaluating microcomputer courseware for vocational and technical education. Through a literature review and contacts with organizations and individuals involved in courseware evaluation and use, project staff identified and acquired for review documents pertaining to courseware evaulation, vocational…

  14. UAS Integration in the NAS Project: Flight Test 3 Data Analysis of JADEM-Autoresolver Detect and Avoid System

    NASA Technical Reports Server (NTRS)

    Gong, Chester; Wu, Minghong G.; Santiago, Confesor

    2016-01-01

    The Unmanned Aircraft Systems Integration in the National Airspace System project, or UAS Integration in the NAS, aims to reduce technical barriers related to safety and operational challenges associated with enabling routine UAS access to the NAS. The UAS Integration in the NAS Project conducted a flight test activity, referred to as Flight Test 3 (FT3), involving several Detect-and-Avoid (DAA) research prototype systems between June 15, 2015 and August 12, 2015 at the Armstrong Flight Research Center (AFRC). This report documents the flight testing and analysis results for the NASA Ames-developed JADEM-Autoresolver DAA system, referred to as 'Autoresolver' herein. Four flight test days (June 17, 18, 22, and July 22) were dedicated to Autoresolver testing. The objectives of this test were as follows: 1. Validate CPA prediction accuracy and detect-and-avoid (DAA, formerly known as self-separation) alerting logic in realistic flight conditions. 2. Validate DAA trajectory model including maneuvers. 3. Evaluate TCAS/DAA interoperability. 4. Inform final Minimum Operating Performance Standards (MOPS). Flight test scenarios were designed to collect data to directly address the objectives 1-3. Objective 4, inform final MOPS, was a general objective applicable to the UAS in the NAS project as a whole, of which flight test is a subset. This report presents analysis results completed in support of the UAS in the NAS project FT3 data review conducted on October 20, 2015. Due to time constraints and, to a lesser extent, TCAS data collection issues, objective 3 was not evaluated in this analysis.

  15. Application of surface enhanced Raman scattering and competitive adaptive reweighted sampling on detecting furfural dissolved in transformer oil

    NASA Astrophysics Data System (ADS)

    Chen, Weigen; Zou, Jingxin; Wan, Fu; Fan, Zhou; Yang, Dingkun

    2018-03-01

    Detecting the dissolving furfural in mineral oil is an essential technical method to evaluate the ageing condition of oil-paper insulation and the degradation of mechanical properties. Compared with the traditional detection method, Raman spectroscopy is obviously convenient and timesaving in operation. This study explored the method of applying surface enhanced Raman scattering (SERS) on quantitative analysis of the furfural dissolved in oil. Oil solution with different concentration of furfural were prepared and calibrated by high-performance liquid chromatography. Confocal laser Raman spectroscopy (CLRS) and SERS technology were employed to acquire Raman spectral data. Monte Carlo cross validation (MCCV) was used to eliminate the outliers in sample set, then competitive adaptive reweighted sampling (CARS) was developed to select an optimal combination of informative variables that most reflect the chemical properties of concern. Based on selected Raman spectral features, support vector machine (SVM) combined with particle swarm algorithm (PSO) was used to set up a furfural quantitative analysis model. Finally, the generalization ability and prediction precision of the established method were verified by the samples made in lab. In summary, a new spectral method is proposed to quickly detect furfural in oil, which lays a foundation for evaluating the ageing of oil-paper insulation in oil immersed electrical equipment.

  16. Detection of coal mine workings using high-resolution earth resistivity techniques. Final technical report, September 1979-September 1980

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Peters, W.R.; Campbell, T.M.; Sturdivant, V.R.

    1980-09-26

    Shallow underground voids resulting from early coal mining and other resource recovery activities over the past several decades are now being recognized as a significant cause of ground subsidence problems in developing urban areas. Uncertain knowledge of abandoned coal mines also imposes potential hazards in coal excavation operations since water inundation or the release of methane gas is a principal hazard when mine excavation operations break into an abandoned mine. US Army requirements for an effective method for detecting and mapping subversive abandoned tunnels have resulted in a surface-operated automatic earth resistivity survey system with a digital computer data processingmore » system. Field tests aimed at demonstrating the system performance resulted in successful detection of tunnels having depth-to-diameter ratios up to 15 to 1. Under the sponsorship of the Bureau of Mines, a similar system was designed and constructed for use in the detection of coal mine workings. This report discusses the hardware and software aspects of the system and the application of the high-resolution earth resistivity method to the survey and mapping of abandoned coal mine workings. In the field tests reported, the targets of interest were both air- and water-filled workings.« less

  17. Final Technical Report, Wind Generator Project (Ann Arbor)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Geisler, Nathan

    A Final Technical Report (57 pages) describing educational exhibits and devices focused on wind energy, and related outreach activities and programs. Project partnership includes the City of Ann Arbor, MI and the Ann Arbor Hands-on Museum, along with additional sub-recipients, and U.S. Department of Energy/Office of Energy Efficiency and Renewable Energy (EERE). Report relays key milestones and sub-tasks as well as numerous graphics and images of five (5) transportable wind energy demonstration devices and five (5) wind energy exhibits designed and constructed between 2014 and 2016 for transport and use by the Ann Arbor Hands-on Museum.

  18. Final Technical Report- Virginia Solar Pathways Project

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bond, Katharine; Cosby, Sarah

    This Report provides a technical review of the final results of a funding award to Virginia Electric and Power Company (Dominion Energy Virginia (DEV) or the Company) for a project under the U.S. Department of Energy’s Solar Energy Technologies Office. The three-year project was formally known as the Virginia Solar Pathways Project (VSPP or the Project). The purpose of the VSPP was to develop a collaborative utility-administered solar strategy (Solar Strategy) for DEV’s service territory in the Commonwealth that could serve as a replicable model for other states with similar policy environments.

  19. Technical interventions to increase adenoma detection rate in colonoscopy.

    PubMed

    Rondonotti, Emanuele; Andrealli, Alida; Amato, Arnaldo; Paggi, Silvia; Conti, Clara Benedetta; Spinzi, Giancarlo; Radaelli, Franco

    2016-12-01

    Adenoma detection rate (ADR) is the most robust colonoscopy quality metric and clinical studies have adopted it as the ideal method to assess the impact of technical interventions. Areas covered: We reviewed papers focusing on the impact of colonoscopy technical issues on ADR, including withdrawal time and technique, second evaluation of the right colon, patient positional changes, gastrointestinal assistant participation during colonoscopy, water-aided technique, optimization of bowel preparation and antispasmodic administration. Expert commentary: Overall, technical interventions are inexpensive, available worldwide and easy to implement. Some of them, such as the adoption of split dose regimen and slow scope withdrawal to allow a careful inspection, have been demonstrated to significantly improve ADR. Emerging data support the use of water-exchange colonoscopy. According to published studies, other technical interventions seem to provide only marginal benefit to ADR. Unfortunately, the available evidence has methodological limitations, such as small sample sizes, the inclusion of expert endoscopists only and the evaluation of single technical interventions. Additionally, larger studies are needed to clarify whether these interventions might have a higher benefit on low adenoma detectors and whether the implementation of a bundle of them, instead of a single technical maneuver, might have a greater impact on ADR.

  20. M-X Environmental Technical Report. Socioeconomic Impact Estimates for White Pine County, Nevada. Detailed Tables.

    DTIC Science & Technology

    1980-12-22

    8217AP0A095 772 HENNINGSON DURHAM AND RICHARDSON SANTA BARBARA CA F/G 16/1 B-B ENVIRONMENTAL TECHNICAL REPORT. SOCIOECONOMIC IMPACT ESTIMA--ETC(U) DEC... Environmental Technical Reports,. 53ocioeconctnic’ Final r1eport Impact . Estimates for White Pine County, Nevada. ____________ Detailed Tables 6. PERFORMING...background information for the analysis contained in the M-X Deploment Area Selection and Land Withirawal/Acquisition Draft Environmental Impact Statement

  1. Optical fiber sensors for materials and structures characterization

    NASA Technical Reports Server (NTRS)

    Lindner, D. K.; Claus, R. O.

    1991-01-01

    The final technical report on Optical Fiber Sensors for Materials and Structures Characterization, covering the period August 1990 through August 1991 is presented. Research programs in the following technical areas are described; sapphire optical fiber sensors; vibration analysis using two-mode elliptical core fibers and sensors; extrinsic Fabry-Perot interferometer development; and coatings for fluorescent-based sensor. Research progress in each of these areas was substantial, as evidenced by the technical publications which are included as appendices.

  2. A joint university-government technical editing program

    NASA Technical Reports Server (NTRS)

    Stohrer, Freda F.; Pinelli, Thomas E.

    1978-01-01

    The NASA Langley Research Center (LaRC) and Old Dominion University have designed a mutually useful technical editing program. A university team made up of an English instructor and two graduate students - one from English, one from engineering - works with a senior editor from LaRC to prepare technical reports for publication. A round-robin technique gives the university team editorial commentary from both language and technical specialists; the senior editor from LaRC supervises reports through final publication. To date, the system has provided LaRC with a respectable product and university students with valuable on-the-job training.

  3. FINAL TECHNICAL REPORT: Underwater Active Acoustic Monitoring Network For Marine And Hydrokinetic Energy Projects

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Stein, Peter J.; Edson, Patrick L.

    2013-12-20

    This project saw the completion of the design and development of a second generation, high frequency (90-120 kHz) Subsurface-Threat Detection Sonar Network (SDSN). The system was deployed, operated, and tested in Cobscook Bay, Maine near the site the Ocean Renewable Power Company TidGen™ power unit. This effort resulted in a very successful demonstration of the SDSN detection, tracking, localization, and classification capabilities in a high current, MHK environment as measured by results from the detection and tracking trials in Cobscook Bay. The new high frequency node, designed to operate outside the hearing range of a subset of marine mammals, wasmore » shown to detect and track objects of marine mammal-like target strength to ranges of approximately 500 meters. This performance range results in the SDSN system tracking objects for a significant duration - on the order of minutes - even in a tidal flow of 5-7 knots, potentially allowing time for MHK system or operator decision-making if marine mammals are present. Having demonstrated detection and tracking of synthetic targets with target strengths similar to some marine mammals, the primary hurdle to eventual automated monitoring is a dataset of actual marine mammal kinematic behavior and modifying the tracking algorithms and parameters which are currently tuned to human diver kinematics and classification.« less

  4. A New Undergraduate Course on the Physics of Space Situational Awareness

    NASA Astrophysics Data System (ADS)

    Jost, T.; Dearborn, M.; Chun, F.; McHarg, G.

    As documented in the National Defense Authorization Act for fiscal year 2010, space situational awareness (SSA) is a high priority for the DoD and intelligence community. A fundamental understanding of the technical issues involved with SSA requires knowledge in many different scientific areas. The mission of the United States Air Force Academy (USAFA) is to educate, train, and inspire men and women to become officers of character motivated to lead the United States Air Force in service to our Nation. The physics department is implementing the USAFA mission and the need for technically competent officers in SSA through a comprehensive SSA Initiative. As part of the Initiative, we are developing a course to provide junior or senior cadets with the scientific background necessary to understand the challenges associated with SSA missions and systems. This presentation introduces the planned course objectives and includes a discussion of topics to be covered. Examples of topics include, optically resolved imaging, radiometry and photometry, radar detection and tracking, orbital prediction, debris and collision avoidance, detection of proximity operations and modeling and simulation tools. Cadets will have hands-on opportunities to collect metrics of a designated object using Academy assets such as the 41 cm telescope. Cadets will convert telescope gimbal angles into an orbital data. Cadets will synthesize what they learned in the course by completing the semester with a final project where the collected data is merged with a notional scenario to present a mock decision briefing. This class will be open to cadets of any academic major, since the intent is to prepare officers with basic technical competence in SSA applications. This is critical since graduates of the Academy become commissioned officers in the military and serve in a large variety of leadership positions -- from the researcher to the warfighter. Since we are currently developing the course, the SSA community will be invited to send online feedback to USAFA physics department faculty and to participate by providing materials that may be integrated into course.

  5. InfoDROUGHT: Technical reliability assessment using crop yield data at the Spanish-national level

    NASA Astrophysics Data System (ADS)

    Contreras, Sergio; Garcia-León, David; Hunink, Johannes E.

    2017-04-01

    Drought monitoring (DM) is a key component of risk-centered drought preparedness plans and drought policies. InfoDROUGHT (www.infosequia.es) is a a site- and user-tailored and fully-integrated DM system which combines functionalities for: a) the operational satellite-based weekly-1km tracking of severity and spatial extent of drought impacts, b) the interactive and faster query and delivery of drought information through a web-mapping service. InfoDROUGHT has a flexible and modular structure. The calibration (threshold definitions) and validation of the system is performed by combining expert knowledge and auxiliary impact assessments and datasets. Different technical solutions (basic or advanced versions) or deployment options (open-standard or restricted-authenticated) can be purchased by end-users and customers according to their needs. In this analysis, the technical reliability of InfoDROUGHT and its performance for detecting drought impacts on agriculture has been evaluated in the 2003-2014 period by exploring and quantifying the relationships among the drought severity indices reported by InfoDROUGHT and the annual yield anomalies observed for different rainfed crops (maize, wheat, barley) at Spain. We hypothesize a positive relationship between the crop anomalies and the drought severity level detected by InfoDROUGHT. Annual yield anomalies were computed at the province administrative level as the difference between the annual yield reported by the Spanish Annual Survey of Crop Acreages and Yields (ESYRCE database) and the mean annual yield estimated during the study period. Yield anomalies were finally compared against drought greenness-based and thermal-based drought indices (VCI and TCI, respectively) to check the coherence of the outputs and the hypothesis stated. InfoDROUGHT has been partly funded by the Spanish Ministry of Economy and Competiveness through a Torres-Quevedo grant, and by the H2020-EU project "Bridging the Gap for Innovations in Disaster Resilience" (www.brigaid.eu).

  6. Mature Programs of Study: Examining Policy Implementation at the Local Level. Final Report

    ERIC Educational Resources Information Center

    Alfeld, Corinne; Bhattacharya, Sharika

    2013-01-01

    The 2006 Carl D. Perkins Career and Technical Education Act required that all career technical education (CTE) programs offer secondary to postsecondary programs of study (POS), which integrate rigorous academics, offer dual enrollment options, and lead to an industry-recognized degree or credential. Focused on improving students' transition to…

  7. 75 FR 37722 - OMB Approvals Under the Paperwork Reduction Act; Technical Amendment

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-30

    ... since its last update. B. Why is this Technical Amendment Issued as a Final Rule? The information... provisions since the last update of this table. The paperwork burden associated with these new provisions was... amendment updates the table that lists the Office of Management and Budget (OMB) control numbers issued...

  8. United States Air Force Training Line Simulator. Final Report.

    ERIC Educational Resources Information Center

    Nauta, Franz; Pierce, Michael B.

    This report describes the technical aspects and potential applications of a computer-based model simulating the flow of airmen through basic training and entry-level technical training. The objective of the simulation is to assess the impacts of alternative recruit classification and training policies under a wide variety of assumptions regarding…

  9. Final recovery plan of the southwestern willow flycatcher (Empidonax traillii extimus)

    Treesearch

    Deborah M. Finch; Stephen I. Rothstein; Jon C. Boren; William L. Graf; Jerry L. Holechek; Barbara E. Kus; Robert M. Marshall; Molly M. Pohl; Susan J. Sferra; Mark K. Sogge; Julie C. Stromberg; Bradley A. Valentine; Mary J. Whitfield; Sartor O. Williams

    2002-01-01

    The Southwestern Willow Flycatcher Recovery Team is composed of a Technical Subgroup (pg. ii), six Implementation Subgroups (Appendix A), and a Tribal Working Group. The Technical Subgroup consists of 14 academic scientists, researchers, and resource managers with a wide range of expertise in avian biology and ecology, southwestern willow flycatcher ecology, cowbird...

  10. Local/State Bilingual Project. 1981-82 Final Technical Report. Appendixes.

    ERIC Educational Resources Information Center

    Austin Independent School District, TX. Office of Research and Evaluation.

    The 1981-82 Local/State Bilingual Program Technical Report addresses the evaluation questions of the Local/State Bilingual Program Evaluation Design. It is organized into six appendixes. Each appendix reports the information collected by a specific measure. Each appendix consists of (1) an instrument description, (2) purpose of the measure, (3)…

  11. 77 FR 26444 - Revisions to Final Response To Petition From New Jersey Regarding SO2

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-04

    ... modeling or other technical analyses and no new analyses were necessary to make the revisions. III. Public... this modeling approach. Therefore, no new technical analyses or any changes to the modeling are...) modeling analysis submitted with the September 2010 petition identified NAAQS violations at receptors in...

  12. 77 FR 45282 - NRC Position on the Relationship Between General Design Criteria and Technical Specification...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-31

    ..., are described in the final safety analysis report (FSAR). The staff safety evaluation documents the acceptability of these analyses, and it is the combination of the FSAR analyses and the staff safety evaluation... analysis, maintain their capability to perform their safety functions. Technical Specification Operability...

  13. A Dissemination Model for New Technical Education Programs. Final Report.

    ERIC Educational Resources Information Center

    Hull, Daniel M.

    The Technical Education Research Center-SW has conceived, tested, and refined a model for disseminating newly developed programs and materials throughout the nation. The model performed successfully in the dissemination of more than 50,000 educational units (modules) of Laser/Electro-Optics Technician (LEOT) materials during a four-year period…

  14. 75 FR 28499 - Medical Certification Requirements as Part of the Commercial Driver's License (CDL); Technical...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-21

    ... Driver's License (CDL); Technical, Organizational, and Conforming Amendments AGENCY: Federal Motor... ``medical examiner's license or certificate number'' to refer to the number on a medical examiner's license... examiner qualifies him or her to drive. This inconsistency has been clarified in today's final rule so that...

  15. A Simulation of DNA Sequencing Utilizing 3M Post-It[R] Notes

    ERIC Educational Resources Information Center

    Christensen, Doug

    2009-01-01

    An inexpensive and equipment free approach to teaching the technical aspects of DNA sequencing. The activity described requires an instructor with a familiarity of DNA sequencing technology but provides a straight forward method of teaching the technical aspects of sequencing in the absence of expensive sequencing equipment. The final sequence…

  16. Installation and Assimilation of Educational Innovations in Vocational/Technical Programs in Post-Secondary Institutions. Final Report.

    ERIC Educational Resources Information Center

    Appel, Victor H.; Roueche, John E.

    The factors which contribute to the successful installation and assimilation of educational innovations were examined in relation to vocational/technical programs in eight post-secondary institutions. About 555 instructors, administrators, and non-teaching professional staff were surveyed regarding the level and extent of use of individualized…

  17. Final Technical Report on the Institute for Advanced Study in Student Personnel Work.

    ERIC Educational Resources Information Center

    Callis, Robert

    This document reports the planning, implementation, and evaluation of a 9-month institute held at the University of Missouri-Columbia to prepare participants (approximately 20) for leadership positions in student personnel work at junior colleges and technical institutes. The following aspects of the instructional program are discussed and…

  18. Demonstration and Research Program for Teaching Young String Players. Final Report.

    ERIC Educational Resources Information Center

    Yarborough, William

    This report explains a system for rapidly training beginning students in the technical aspects of playing a stringed instrument. The program also affords them a well-rounded, basic knowledge of music. A "numerical" method of notation and concentrated muscular exercises greatly speeded the technical learning process. The daily coordination of ear…

  19. Special Project for Research Training in Vocational Education: Research Training Series. Final Report.

    ERIC Educational Resources Information Center

    Vivian, Neal E.

    To upgrade research and research utilization competence of vocational educators, The Center for Vocational and Technical Education and The American Vocational Association planned four 1-week research training programs on: (1) Planning Vocational/Technical Education Programs Based on Manpower Research, (2) Patterns of Career Development as Applied…

  20. 78 FR 4030 - Designation of Low-Income Status; Acceptance of Secondary Capital Accounts by Low-Income...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-18

    ... writing that it wishes to accept the designation. The final rule extends an FCU's response time from 30..., nonsubstantive technical amendments to NCUA's requirements for insurance regulation to reflect current agency... requirements for insurance regulation. These technical corrections are necessary to reflect current agency...

  1. SURVEY OF INFORMATION ON VOCATIONAL AND TECHNICAL EDUCATION IN THE STATE OF ILLINOIS. FINAL REPORT.

    ERIC Educational Resources Information Center

    Corplan Associates, Chicago, IL. Technology Center.

    THE BASIC OBJECTIVE OF THE SURVEY WAS TO GATHER INFORMATION HELPFUL IN PLANNING AND DEVELOPING VOCATIONAL AND TECHNICAL EDUCATION PRIMARILY WITHIN THE PUBLIC SCHOOL SYSTEM. OCCUPATIONAL NEEDS WERE IDENTIFIED FROM FORECASTS OF CHANGES IN CURRENT OCCUPATIONS, AN ANALYSIS OF THE IMPLICATIONS OF SCIENTIFIC AND TECHNOLOGICAL DEVELOPMENTS, AND…

  2. 75 FR 47211 - Navigation and Navigable Waters; Technical, Organizational, and Conforming Amendments, Sector...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-05

    ... Puget Sound, WA AGENCY: Coast Guard, DHS. ACTION: Final rule. SUMMARY: This rule makes non-substantive... technical corrections to reflect the renaming of Sector Seattle to Sector Puget Sound as part of the Coast... organizational structure. Sector Seattle has been disestablished and Sector Puget Sound has been established in...

  3. Statewide Curriculum Articulation Project for Vocational-Technical Education in Minnesota. Final Report.

    ERIC Educational Resources Information Center

    Burger, Laura J.; And Others

    The goal of this project was to develop, validate, and utilize a process for vertically articulating curriculum between secondary and post secondary levels of vocational technical education throughout the state of Minnesota. Procedures involved the identification of two areas of staff responsibility: research and development, and service to local…

  4. Delivery of Instruction via Television. Final Report.

    ERIC Educational Resources Information Center

    Wisconsin State Board of Vocational, Technical, and Adult Education, Madison.

    During 1985, the Wisconsin Board of Vocational, Technical, and Adult Education (VTAE) expanded its delivery of instruction via television. Approximately 3,000 persons at 170 sites throughout the United States and Canada participated in the VTAE's Technical School of the Air. In addition to delivering six to eight courses per semester, the network…

  5. O*NET Final Technical Report. Volume I [and] Volume II [and] Volume III.

    ERIC Educational Resources Information Center

    Peterson, Norman G.; Mumford, Michael D.; Borman, Walter C.; Jeanneret, P. Richard; Fleishman, Edwin A.; Levin, Kerry Y.

    This document contains the three volumes of the technical report for development of the prototype of the Occupational Information Network (O*NET), which is intended to replace the "Dictionary of Occupational Titles.""General Introduction" (Norman G. Peterson) presents an overview of O*NET's purpose, content, and structure.…

  6. 78 FR 34920 - Technical Amendments To Reflect the Authorizing Legislation of the Institute of Museum and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-11

    ... NATIONAL FOUNDATION ON THE ARTS AND THE HUMANITIES Institute of Museum and Library Services 45 CFR... Museum and Library Services AGENCY: Institute of Museum and Library Services (IMLS), NFAH. ACTION: Technical amendment; final rule. SUMMARY: The Institute of Museum and Library amends its grants regulations...

  7. Final report on technical work accomplished under contract NASw-2953

    NASA Technical Reports Server (NTRS)

    Fredricks, R. W.

    1977-01-01

    A report is given on the technical work accomplished in the area of plasma physics. The subjects covered are: (1) oblique whistler instabilities, (2) current-limited electron beam injection, (3) three-dimensional ion sound turbulence, (4) theoretical aspects of sounder antenna operation and (5) whistler modes in bow shock structures.

  8. Development of German-English Machine Translation System. Final Technical Report.

    ERIC Educational Resources Information Center

    Lehmann, Winfred P.; Stachowitz, Rolf A.

    This report describes work on a pilot system for a fully automatic, high-quality translation of German scientific and technical text into English and gives the results of an experiment designed to show the system's capability to produce quality mechanical translation. The areas considered were: (1) grammar formalism, mainly involving the addition…

  9. The Technical and Biological Reproducibility of Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry (MALDI-TOF MS) Based Typing: Employment of Bioinformatics in a Multicenter Study

    PubMed Central

    Oberle, Michael; Wohlwend, Nadia; Jonas, Daniel; Maurer, Florian P.; Jost, Geraldine; Tschudin-Sutter, Sarah; Vranckx, Katleen; Egli, Adrian

    2016-01-01

    Background The technical, biological, and inter-center reproducibility of matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI TOF MS) typing data has not yet been explored. The aim of this study is to compare typing data from multiple centers employing bioinformatics using bacterial strains from two past outbreaks and non-related strains. Material/Methods Participants received twelve extended spectrum betalactamase-producing E. coli isolates and followed the same standard operating procedure (SOP) including a full-protein extraction protocol. All laboratories provided visually read spectra via flexAnalysis (Bruker, Germany). Raw data from each laboratory allowed calculating the technical and biological reproducibility between centers using BioNumerics (Applied Maths NV, Belgium). Results Technical and biological reproducibility ranged between 96.8–99.4% and 47.6–94.4%, respectively. The inter-center reproducibility showed a comparable clustering among identical isolates. Principal component analysis indicated a higher tendency to cluster within the same center. Therefore, we used a discriminant analysis, which completely separated the clusters. Next, we defined a reference center and performed a statistical analysis to identify specific peaks to identify the outbreak clusters. Finally, we used a classifier algorithm and a linear support vector machine on the determined peaks as classifier. A validation showed that within the set of the reference center, the identification of the cluster was 100% correct with a large contrast between the score with the correct cluster and the next best scoring cluster. Conclusions Based on the sufficient technical and biological reproducibility of MALDI-TOF MS based spectra, detection of specific clusters is possible from spectra obtained from different centers. However, we believe that a shared SOP and a bioinformatics approach are required to make the analysis robust and reliable. PMID:27798637

  10. Day one sustainability

    NASA Astrophysics Data System (ADS)

    Orr, John; Ibell, Timothy; Evernden, Mark; Darby, Antony

    2015-05-01

    Emissions reductions targets for the UK set out in the Climate Change Act for the period to 2050 will only be achieved with significant changes to the built environment, which is currently estimated to account for 50% of the UK's carbon emissions. The socio-technological nature of Civil Engineering means that this field is uniquely placed to lead the UK through such adaptations. This paper discusses the importance of interdisciplinary teaching to produce multi-faceted team approaches to sustainable design solutions. Methods for measuring success in education are often not fit for purpose, producing good students but poor engineers. Real-world failures to apply sustainable design present a serious, difficult to detect, and ultimately economically negative situation. Techniques to replace summative examinations are presented and discussed, with the aim of enhancing core technical skills alongside those required for sustainable design. Finally, the role of our future engineers in policy-making is discussed. In addition to carbon, the provision of water and food will heavily influence the work of civil engineers in the coming decades. Leadership from civil engineers with the technical knowledge and social awareness to tackle these issues will be required. This provides both opportunities and challenges for engineering education in the UK.

  11. Scaling production and improving efficiency in DEA: an interactive approach

    NASA Astrophysics Data System (ADS)

    Rödder, Wilhelm; Kleine, Andreas; Dellnitz, Andreas

    2017-10-01

    DEA models help a DMU to detect its (in-)efficiency and to improve activities, if necessary. Efficiency is only one economic aim for a decision-maker; however, up- or downsizing might be a second one. Improving efficiency is the main topic in DEA; the long-term strategy towards the right production size should attract our attention as well. Not always the management of a DMU primarily focuses on technical efficiency but rather is interested in gaining scale effects. In this paper, a formula for returns to scale (RTS) is developed, and this formula is even applicable for interior points of technology. Particularly, technical and scale inefficient DMUs need sophisticated instruments to improve their situation. Considering RTS as well as efficiency, in this paper, we give an advice for each DMU to find an economically reliable path from its actual situation to better activities and finally to most productive scale size (mpss), perhaps. For realizing this path, we propose an interactive algorithm, thus harmonizing the scientific findings and the interests of the management. Small numerical examples illustrate such paths for selected DMUs; an empirical application in theatre management completes the contribution.

  12. The Independent Technical Analysis Process Final Report 2006-2007.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Duberstein, Corey; Ham, Kenneth; Dauble, Dennis

    2007-03-01

    The Bonneville Power Administration (BPA) contracted with the Pacific Northwest National Laboratory (PNNL) to provide technical analytical support for system-wide fish passage information (BPA Project No. 2006-010-00). The goal of this project was to produce rigorous technical analysis products using independent analysts and anonymous peer reviewers. This project provided an independent technical source for non-routine fish passage analyses while allowing routine support functions to be performed by other well-qualified entities. The Independent Technical Analysis Process (ITAP) was created to provide non-routine analysis for fish and wildlife agencies and tribes in particular and the public in general on matters related tomore » juvenile and adult salmon and steelhead passage through the mainstem hydrosystem. The process was designed to maintain the independence of analysts and reviewers from parties requesting analyses, to avoid potential bias in technical products. The objectives identified for this project were to administer a rigorous, transparent process to deliver unbiased technical assistance necessary to coordinate recommendations for storage reservoir and river operations that avoid potential conflicts between anadromous and resident fish. Seven work elements, designated by numbered categories in the Pisces project tracking system, were created to define and accomplish project goals as follows: (1) 118 Coordination - Coordinate technical analysis and review process: (a) Retain expertise for analyst/reviewer roles. (b) Draft research directives. (c) Send directive to the analyst. (d) Coordinate two independent reviews of the draft report. (e) Ensure reviewer comments are addressed within the final report. (2) 162 Analyze/Interpret Data - Implement the independent aspects of the project. (3) 122 Provide Technical Review - Implement the review process for the analysts. (4) 132 Produce Annual Report - FY06 annual progress report with Pisces Disseminate (5) 161 Disseminate Raw/Summary Data and Results - Post technical products on the ITAP web site. (6) 185-Produce Pisces Status Report - Provide periodic status reports to BPA. (7) 119 Manage and Administer Projects - project/contract administration.« less

  13. Boron neutron capture therapy (BNCT) in Finland: technological and physical prospects after 20 years of experiences.

    PubMed

    Savolainen, Sauli; Kortesniemi, Mika; Timonen, Marjut; Reijonen, Vappu; Kuusela, Linda; Uusi-Simola, Jouni; Salli, Eero; Koivunoro, Hanna; Seppälä, Tiina; Lönnroth, Nadja; Välimäki, Petteri; Hyvönen, Heini; Kotiluoto, Petri; Serén, Tom; Kuronen, Antti; Heikkinen, Sami; Kosunen, Antti; Auterinen, Iiro

    2013-05-01

    Boron Neutron Capture Therapy (BNCT) is a binary radiotherapy method developed to treat patients with certain malignant tumours. To date, over 300 treatments have been carried out at the Finnish BNCT facility in various on-going and past clinical trials. In this technical review, we discuss our research work in the field of medical physics to form the groundwork for the Finnish BNCT patient treatments, as well as the possibilities to further develop and optimize the method in the future. Accordingly, the following aspects are described: neutron sources, beam dosimetry, treatment planning, boron imaging and determination, and finally the possibilities to detect the efficacy and effects of BNCT on patients. Copyright © 2012 Associazione Italiana di Fisica Medica. Published by Elsevier Ltd. All rights reserved.

  14. Infrared Absorption Spectroscopy and Chemical Kinetics of Free Radicals, Final Technical Report

    DOE R&D Accomplishments Database

    Curl, Robert F.; Glass, Graham P.

    2004-11-01

    This research was directed at the detection, monitoring, and study of the chemical kinetic behavior by infrared absorption spectroscopy of small free radical species thought to be important intermediates in combustion. Work on the reaction of OH with acetaldehyde has been completed and published and work on the reaction of O({sup 1}D) with CH{sub 4} has been completed and submitted for publication. In the course of our investigation of branching ratios of the reactions of O({sup 1}D) with acetaldehyde and methane, we discovered that hot atom chemistry effects are not negligible at the gas pressures (13 Torr) initially used. Branching ratios of the reaction of O({sup 1}D) with CH{sub 4} have been measured at a tenfold higher He flow and fivefold higher pressure.

  15. Non-invasive current and voltage imaging techniques for integrated circuits using scanning probe microscopy. Final report, LDRD Project FY93 and FY94

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Campbell, A.N.; Cole, E.I. Jr.; Tangyunyong, Paiboon

    This report describes the first practical, non-invasive technique for detecting and imaging currents internal to operating integrated circuits (ICs). This technique is based on magnetic force microscopy and was developed under Sandia National Laboratories` LDRD (Laboratory Directed Research and Development) program during FY 93 and FY 94. LDRD funds were also used to explore a related technique, charge force microscopy, for voltage probing of ICs. This report describes the technical work performed under this LDRD as well as the outcomes of the project in terms of publications and awards, intellectual property and licensing, synergistic work, potential future work, hiring ofmore » additional permanent staff, and benefits to DOE`s defense programs (DP).« less

  16. Site Operator technical report. Final report (1992--1996)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    NONE

    1996-12-01

    The Southern California Edison Company (SCE) and the US Department of Energy (DOE) entered into cooperative agreement No. DE-FC07-91ID13077 on August 23, 1991, which expired on August 3, 1996. This cooperative agreement provided SCE with DOE cofunding for participation in the DOE`s Electric and Hybrid Vehicle Site Operator Program. In return, SCE provided the DOE with quarterly progress reports which include operating and maintenance data for the electric (EVs) vehicles in SCE`s fleet. Herein is SCE`s final report for the 1992 to 1996 agreement period. As of September 1, 1996 the SCE fleet had 65 electric vehicles in service. Amore » total of 578,200 miles had been logged. During the agreement period, SCE sent the DOE a total of 19 technical reports (Appendix B). This report summarizes the technical achievements which took place during a long, productive and rewarding, relationship with the DOE.« less

  17. Current Technical Approaches for the Early Detection of Foodborne Pathogens: Challenges and Opportunities.

    PubMed

    Cho, Il-Hoon; Ku, Seockmo

    2017-09-30

    The development of novel and high-tech solutions for rapid, accurate, and non-laborious microbial detection methods is imperative to improve the global food supply. Such solutions have begun to address the need for microbial detection that is faster and more sensitive than existing methodologies (e.g., classic culture enrichment methods). Multiple reviews report the technical functions and structures of conventional microbial detection tools. These tools, used to detect pathogens in food and food homogenates, were designed via qualitative analysis methods. The inherent disadvantage of these analytical methods is the necessity for specimen preparation, which is a time-consuming process. While some literature describes the challenges and opportunities to overcome the technical issues related to food industry legal guidelines, there is a lack of reviews of the current trials to overcome technological limitations related to sample preparation and microbial detection via nano and micro technologies. In this review, we primarily explore current analytical technologies, including metallic and magnetic nanomaterials, optics, electrochemistry, and spectroscopy. These techniques rely on the early detection of pathogens via enhanced analytical sensitivity and specificity. In order to introduce the potential combination and comparative analysis of various advanced methods, we also reference a novel sample preparation protocol that uses microbial concentration and recovery technologies. This technology has the potential to expedite the pre-enrichment step that precedes the detection process.

  18. 7 CFR 1944.419 - Final grantee evaluation.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ...) PROGRAM REGULATIONS (CONTINUED) HOUSING Self-Help Technical Assistance Grants § 1944.419 Final grantee... Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, RURAL BUSINESS..., application, this regulation, and any amendments. (a) This is a quantitative evaluation of the grantee to...

  19. Near Real-Time Optimal Prediction of Adverse Events in Aviation Data

    NASA Technical Reports Server (NTRS)

    Martin, Rodney Alexander; Das, Santanu

    2010-01-01

    The prediction of anomalies or adverse events is a challenging task, and there are a variety of methods which can be used to address the problem. In this paper, we demonstrate how to recast the anomaly prediction problem into a form whose solution is accessible as a level-crossing prediction problem. The level-crossing prediction problem has an elegant, optimal, yet untested solution under certain technical constraints, and only when the appropriate modeling assumptions are made. As such, we will thoroughly investigate the resilience of these modeling assumptions, and show how they affect final performance. Finally, the predictive capability of this method will be assessed by quantitative means, using both validation and test data containing anomalies or adverse events from real aviation data sets that have previously been identified as operationally significant by domain experts. It will be shown that the formulation proposed yields a lower false alarm rate on average than competing methods based on similarly advanced concepts, and a higher correct detection rate than a standard method based upon exceedances that is commonly used for prediction.

  20. ECLSS medical support activities

    NASA Technical Reports Server (NTRS)

    Crump, William J.; Kilgore, Melvin V., Jr.

    1991-01-01

    During the period from April 10, 1990 to April 9, 1991, the Consortium for the Space Life Sciences provided technical assistance to the NASA/MSFC water recovery efforts. This assistance was in the form of literature reviews, technical recommendations, and presentations. This final report summarizes the activities completed during this period and identifies those areas requiring additional efforts. The tasks which the University of Alabama in Huntsville (UAH) water recovery team addressed were either identified by MSFC technical representatives or chosen from those outlined in the subject statement of work.

  1. Switching gears and changing lanes

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hammock, Earlene C.

    2002-01-01

    From musing over Shakespeare's fine lines and metaphors to teaching technical writing and editing, and finally, to cranking out scientific and technical documents, writing articles, and editing publications-how'd a nice girl like me end up in a place like this? Twice, after having prepared for an academic career of teaching and research, I found myself in a technical communications position-first, at the University of Texas at El Paso College of Engineering and later, at Los Alamos National Laboratory. What happened?

  2. A Socio-Technical Approach to Preventing, Mitigating, and Recovering from Ransomware Attacks.

    PubMed

    Sittig, Dean F; Singh, Hardeep

    2016-01-01

    Recently there have been several high-profile ransomware attacks involving hospitals around the world. Ransomware is intended to damage or disable a user's computer unless the user makes a payment. Once the attack has been launched, users have three options: 1) try to restore their data from backup; 2) pay the ransom; or 3) lose their data. In this manuscript, we discuss a socio-technical approach to address ransomware and outline four overarching steps that organizations can undertake to secure an electronic health record (EHR) system and the underlying computing infrastructure. First, health IT professionals need to ensure adequate system protection by correctly installing and configuring computers and networks that connect them. Next, the health care organizations need to ensure more reliable system defense by implementing user-focused strategies, including simulation and training on correct and complete use of computers and network applications. Concomitantly, the organization needs to monitor computer and application use continuously in an effort to detect suspicious activities and identify and address security problems before they cause harm. Finally, organizations need to respond adequately to and recover quickly from ransomware attacks and take actions to prevent them in future. We also elaborate on recommendations from other authoritative sources, including the National Institute of Standards and Technology (NIST). Similar to approaches to address other complex socio-technical health IT challenges, the responsibility of preventing, mitigating, and recovering from these attacks is shared between health IT professionals and end-users.

  3. A Socio-Technical Approach to Preventing, Mitigating, and Recovering from Ransomware Attacks

    PubMed Central

    Singh, Hardeep

    2016-01-01

    Summary Recently there have been several high-profile ransomware attacks involving hospitals around the world. Ransomware is intended to damage or disable a user’s computer unless the user makes a payment. Once the attack has been launched, users have three options: 1) try to restore their data from backup; 2) pay the ransom; or 3) lose their data. In this manuscript, we discuss a socio-technical approach to address ransomware and outline four overarching steps that organizations can undertake to secure an electronic health record (EHR) system and the underlying computing infrastructure. First, health IT professionals need to ensure adequate system protection by correctly installing and configuring computers and networks that connect them. Next, the health care organizations need to ensure more reliable system defense by implementing user-focused strategies, including simulation and training on correct and complete use of computers and network applications. Concomitantly, the organization needs to monitor computer and application use continuously in an effort to detect suspicious activities and identify and address security problems before they cause harm. Finally, organizations need to respond adequately to and recover quickly from ransomware attacks and take actions to prevent them in future. We also elaborate on recommendations from other authoritative sources, including the National Institute of Standards and Technology (NIST). Similar to approaches to address other complex socio-technical health IT challenges, the responsibility of preventing, mitigating, and recovering from these attacks is shared between health IT professionals and end-users. PMID:27437066

  4. NASA/DOD Aerospace Knowledge Diffusion Research Project. Paper 32: A new era in international technical communication: American-Russian collaboration

    NASA Technical Reports Server (NTRS)

    Flammia, Madelyn; Barclay, Rebecca O.; Pinelli, Thomas E.; Keene, Michael L.; Burger, Robert H.; Kennedy, John M.

    1993-01-01

    Until the recent dissolution of the Soviet Union, the Communist Party exerted a strict control of access to and dissemination of scientific and technical information (STI). This article presents models of the Soviet-style information society and the Western-style information society and discusses the effects of centralized governmental control of information on Russian technical communication practices. The effects of political control on technical communication are then used to interpret the results of a survey of Russian and U.S. aerospace engineers and scientists concerning the time devoted to technical communication, their collaborative writing practices and their attitudes toward collaboration, the kinds of technical documents they produce and use, their views regarding the appropriate content for an undergraduate technical communication course, and their use of computer technology. Finally, the implications of these findings for future collaboration between Russian and U.S. engineers and scientists are examined.

  5. NASA/DoD Aerospace Knowledge Diffusion Research Project. XXXII - A new era in international technical communication: American-Russian collaboration

    NASA Technical Reports Server (NTRS)

    Flammia, Madelyn; Barclay, Rebecca O.; Pinelli, Thomas E.; Keene, Michael L.; Burger, Robert H.; Kennedy, John M.

    1993-01-01

    Until the recent dissolution of the Soviet Union, the Communist Party exerted a strict control of access to and dissemination of scientific and technical information. This article presents models of the Soviet-style information society and the Western-style information society and discusses the effects of centralized governmental control of information on Russian technical communication practices. The effects of political control on technical communication are then used to interpret the results of a survey of Russian and U.S. aerospace engineers and scientists concerning the time devoted to technical communication, their collaborative writing practices and their attitudes toward collaboration, the kinds of technical documents they produce and use, their views regarding the appropriate content for an undergraduate technical communication course, and their use of computer technology. Finally, the implications of these findings for future collaboration between Russian and U.S. engineers and scientists are examined.

  6. Pattern uniformity control in integrated structures

    NASA Astrophysics Data System (ADS)

    Kobayashi, Shinji; Okada, Soichiro; Shimura, Satoru; Nafus, Kathleen; Fonseca, Carlos; Biesemans, Serge; Enomoto, Masashi

    2017-03-01

    In our previous paper dealing with multi-patterning, we proposed a new indicator to quantify the quality of final wafer pattern transfer, called interactive pattern fidelity error (IPFE). It detects patterning failures resulting from any source of variation in creating integrated patterns. IPFE is a function of overlay and edge placement error (EPE) of all layers comprising the final pattern (i.e. lower and upper layers). In this paper, we extend the use cases with Via in additional to the bridge case (Block on Spacer). We propose an IPFE budget and CD budget using simple geometric and statistical models with analysis of a variance (ANOVA). In addition, we validate the model with experimental data. From the experimental results, improvements in overlay, local-CDU (LCDU) of contact hole (CH) or pillar patterns (especially, stochastic pattern noise (SPN)) and pitch walking are all critical to meet budget requirements. We also provide a special note about the importance of the line length used in analyzing LWR. We find that IPFE and CD budget requirements are consistent to the table of the ITRS's technical requirement. Therefore the IPFE concept can be adopted for a variety of integrated structures comprising digital logic circuits. Finally, we suggest how to use IPFE for yield management and optimization requirements for each process.

  7. RTO Technical Report: A Quarterly Listing

    NASA Technical Reports Server (NTRS)

    2002-01-01

    This is a listing of recent unclassified RTO technical publications processed by the NASA Center for AeroSpace Information from April 1,2002 through June 30, 2002. Topics covered include: intrusion detection and design loads for aircraft.

  8. Communication Platform Payload Definition (CPPD) study. Volume 2: Technical report

    NASA Technical Reports Server (NTRS)

    Hunter, E. M.; Driggers, T.; Jorasch, R.

    1986-01-01

    This is Volume 2 (Technical Report) of the Ford Aerospace & Communications Corporation Final Report for the Communication Platform Payload Definition (CPPD) Study program conducted for NASA Lewis Research Center under contract No. NAS3-24235. This report presents the results of the study effort leading to five potential platform payloads to service CONUS and WARC Region 2 traffic demand as projected to the year 2008. The report addresses establishing the data bases, developing service aggregation scenarios, selecting and developing 5 payload concepts, performing detailed definition of the 5 payloads, costing them, identifying critical technology, and finally comparing the payloads with each other and also with non-aggregated equivalent services.

  9. Best Practices for Continuous Monitoring of Temperature and Flow in Wadeable Streams (Final Report)

    EPA Science Inventory

    This final report is a technical "best practices" document describing sensor deployment for and collection of continuous temperature and flow data at ungaged sites in wadeable streams. This document addresses questions related to equipment needs; configuration, placement, and ins...

  10. Hazardous Waste Management System - Identification and Listing of Hazardous Waste - Recycled Used Oil Management Standards - Federal Register Notice, May 3, 1993

    EPA Pesticide Factsheets

    This action corrects several technical errors and provides clarifying amendments to the final recycled used oil management standards rule. The final rule was published on September 10, 1992 (57 FR 41566).

  11. 75 FR 6839 - Technical Service Provider Assistance

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-12

    ... Executive Order 12866, the Office of Management and Budget determined that this final rule is not a... or are eligible to participate in conservation programs to help them make land management decisions...: Covered Programs. The interim final rule incorporated reference to the Agricultural Management Assistance...

  12. Charlotte Circle Outreach. Final Report.

    ERIC Educational Resources Information Center

    Calhoun, Mary Lynne; Rose, Terry L.; Prendergast, Donna

    This final report details the activities of the Charlotte Circle Outreach, a program designed to provide technical assistance and training to early intervention programs offering services to infants and young children with substantial disabilities, ages birth through two years. This mission was accomplished through cooperative planning with…

  13. Determination of the Biologically Relevant Sampling Depth for Terrestrial and Aquatic Ecological Risk Assessments (Final Report)

    EPA Science Inventory

    The Ecological Risk Assessment Support Center (ERASC) announced the release of the final report, Determination of the Biologically Relevant Sampling Depth for Terrestrial and Aquatic Ecological Risk Assessments. This technical paper provides defensible approximations fo...

  14. A Program of Technical Assistance to Industry in Twenty-Six Mississippi Counties and the Choctaw Indian Reservation. Final Report.

    ERIC Educational Resources Information Center

    Phillips, Jane; Sewell, Charles

    A broad technical assistance program has been established in 25 EDA (Economic Development Administration) contract counties and on the Choctaw Indian Reservation Nashoba County) to stimulate new job opportunities by solving operational problems which limit the expansion and diversification of existing industry; professional services in evaluating…

  15. For Work-Force Training, a Plan to Give College Credit Where It's Due

    ERIC Educational Resources Information Center

    Sander, Libby

    2008-01-01

    After nearly three years of planning, Ohio's higher-education officials are finalizing an ambitious program to grant college credit for some technical courses offered at the state's adult-education centers. The program, called the Career-Technical Credit Transfer, is the latest in a string of state efforts to more closely link work-force training…

  16. Improving the Dissemination of Scientific and Technical Information: A Practitioner's Guide to Innovation. (Final Report).

    ERIC Educational Resources Information Center

    Capital Systems Group, Inc., Rockville, MD.

    The aim of this guide is to alert persons with an operational interest in scientific communication to new ideas, techniques, and equipment in the field of communication media and publications. The focus is on the dissemination of scientific information via the technical journal or its equivalent. Secondary dissemination of information such as…

  17. Unified Technical Concepts--Phase II. Expand Application to Industrial Technologies and Adult Education. Final Report.

    ERIC Educational Resources Information Center

    Technical Education Research Center, Waco, TX.

    A project was conducted to develop a laboratory-based instructional system in physics for two-year technician programs that emphasizes both the analogies between basic physical principles and the applications of the principles in modern technology. The Unified Technical Concepts (UTC) system that was developed is (1) a reorganization of physics…

  18. THE DEVELOPMENT OF ACHIEVEMENT MEASURES FOR TRADE AND TECHNICAL EDUCATION. PROGRESS REPORT NUMBER THREE.

    ERIC Educational Resources Information Center

    BALDWIN, THOMAS S.

    DURING THIS PERIOD FROM SEPTEMBER 1 THROUGH NOVEMBER 30, 1966, 35 FIELD CONSULTANTS COMPLETED ANALYSIS OF THEIR INDIVIDUAL TRADE AND TECHNICAL CURRICULUMS. THESE ANALYSES WERE DEVELOPED INTO AN OUTLINE TO SERVE AS A GUIDE FOR DEVELOPING ACHIEVEMENT TESTS. THE FINAL OUTLINE WAS DIVIDED INTO AS MANY DIFFERENT AREAS AS THE CONSULTANTS FELT NECESSARY…

  19. Word Lists to Simplify Vocabulary of Technical Information. Final Report.

    ERIC Educational Resources Information Center

    Kincaid, J. Peter; And Others

    This report describes eight word lists developed for use as part of the computer readability editing system (CRES), which was developed to serve as an author's aid in improving the ease of comprehending Navy technical manuals and training materials. The system has features which flag uncommon and misspelled words and long sentences, suggest simple…

  20. 77 FR 1889 - Drivers of CMVs: Restricting the Use of Cellular Phones; Technical Amendment

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-12

    ... DEPARTMENT OF TRANSPORTATION Federal Motor Carrier Safety Administration 49 CFR Part 391 [Docket No. FMCSA-2010-0096] RIN 2126-AB29 Drivers of CMVs: Restricting the Use of Cellular Phones; Technical... Cellular Phones final rule (76 FR 75470) had a clerical error in Sec. 391.15(f)(1) that stated ``paragraph...

  1. 27 Years of Impact: Vocational-Technical Education in Ohio. Final Annual Report under Federal Law.

    ERIC Educational Resources Information Center

    Ohio State Council on Vocational Education, Westerville.

    The Ohio Council on Vocational Education (OCOVE) was created to strengthen the career, vocational, and technical education services provided for Ohioans as a practical, efficient, and sure way to enhance the competitiveness of individual workers and the state and national economy. Some of the accomplishments of OCOVE during its 27 years of…

  2. Vocational-Technical Education Interface with Ohio's High Technology Business and Industrial Sector. Final Report.

    ERIC Educational Resources Information Center

    McCormick, Robert W.

    This study explored the relationship of vocational-technical educational institutions in Ohio with business and industry using high-technology applications. The study attempted to determine what high-technology applications will be adopted by Ohio's business and industry in the next 5 years, what experience the schools have had in working with…

  3. National Institute of Statistical Sciences Data Confidentiality Technical Panel: Final Report. NCES 2011-608

    ERIC Educational Resources Information Center

    Karr, Alan

    2011-01-01

    NCES asked the National Institute of Statistical Sciences (NISS) to convene a technical panel of survey and policy experts to examine the NCES current and planned data dissemination strategies for confidential data with respect to: mandates and directives that NCES make data available; current and prospective technologies for protecting and…

  4. [Municipalities as a Model for New Careers and Redirection of Vocational-Technical Education Programs.] Final Report.

    ERIC Educational Resources Information Center

    Institute for Local Self Government, Berkeley, CA.

    To meet the manpower needs of local governments, the model developed for this project redirects national and technical education toward new careers programs. Designed by task forces of professional personnel, the model utilizes existing local government resources, including funds for new career activities. Accomplishments of the project include:…

  5. Social Science Research Institutes in the Quality American University. Final Technical Report.

    ERIC Educational Resources Information Center

    Totman, Theodore L.

    The technical report presents a chapter outline and thesis summary of an investigation of social science research institutes in American universities. The bulk of the report presents the thesis in four sections. Section I proposes a typology of organized social research units (OSRUs) in the 11 universities studied. Dimensions used to classify the…

  6. Expanding Horizons: A Program for Students Entering Nontraditional Technical Occupations. PY95 Final Detailed Report.

    ERIC Educational Resources Information Center

    Austin Community Coll., TX.

    The Expanding Horizons Project at Austin Community College successfully achieved its goals for Project Year 1994-95. During the year, the project accomplished the following: raised public awareness of the need to overcome gender bias, promoted career opportunities in nontraditional technical occupations to more than 1,200 prospective students,…

  7. Technical Assistance and Training from the Document Design Project. Final Report.

    ERIC Educational Resources Information Center

    American Institutes for Research, Washington, DC.

    Contained in this report is a description of the technical assistance and training phase of the Document Design Project, a program funded by the National Institute of Education and intended to address and correct the readability problems posed by public documents. The first section of the report provides background material on the assistance and…

  8. Determining and Validating Barriers to Post-Secondary Vocational, Technical and Adult Education Programs in Wisconsin. Final Report.

    ERIC Educational Resources Information Center

    Farning, Max; Borden, Sally

    A consortium of five Wisconsin Vocational, Technical, and Adult Education (VTAE) Districts (Gateway, Indianhead, Mid-State, Milwaukee, and Southwest) were utilized to identify, verify, and alleviate barriers to enrollment. A VTAE survey in 1976 identified six major reasons for individuals' failing to attend school after indicating an interest in…

  9. Sociometric Clique Identification. Final Report.

    ERIC Educational Resources Information Center

    Kadushin, Charles

    This report consists of four parts. The first part is a non-technical summary of the basic problem and an attempted solution. The second part is a technical review of the literature and a description of the basic algorithm used in the solution. The third part describes the use of the Sociogram System. The fourth part describes the use of CHAIN, a…

  10. An Assessment of Workplace Skills Acquired by Students of Vocational and Technical Education Institutions

    ERIC Educational Resources Information Center

    Bakar, Ab Rahim; Mohamed, Shamsiah; Hamzah, Ramlah

    2013-01-01

    This study was performed to identify the employability skills of technical students from the Industrial Training Institutes (ITI) and Indigenous People's Trust Council (MARA) Skills Training Institutes (IKM) in Malaysia. The study sample consisted of 850 final year trainees of IKM and ITI. The sample was chosen by a random sampling procedure from…

  11. Wisconsin Technical College System Board Equity Staff Development Workshops and Services--Phase IV. Final Report.

    ERIC Educational Resources Information Center

    Baldus, Lorayne

    A staff development program on gender equity was conducted for personnel in Wisconsin's technical colleges using the train-the-trainer method. The training took two approaches: a class for college personnel and career challenge training for project directors of single parent and displaced homemaker grants. The inservice class resulted in increased…

  12. A Technical, User and Cost Comparison Study of Microfiche Duplicate Film Material. Final Report.

    ERIC Educational Resources Information Center

    Prevel, James J.

    A technical, user and cost comparison study was undertaken to provide the Educational Resources Information Clearinghouse (ERIC) staff with data on silver halide, diazo, and vesicular type films for microfiche duplication. This information will allow ERIC to determine if diazo and/or vesicular films should be considered in producing ERIC duplicate…

  13. Building Diagnostic Market Deployment - Final Report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Katipamula, S.; Gayeski, N.

    2012-04-30

    Operational faults are pervasive across the commercial buildings sector, wasting energy and increasing energy costs by up to about 30% (Mills 2009, Liu et al. 2003, Claridge et al. 2000, Katipamula and Brambley 2008, and Brambley and Katipamula 2009). Automated fault detection and diagnostic (AFDD) tools provide capabilities essential for detecting and correcting these problems and eliminating the associated energy waste and costs. The U.S. Department of Energy's (DOE) Building Technology Program (BTP) has previously invested in developing and testing of such diagnostic tools for whole-building (and major system) energy use, air handlers, chillers, cooling towers, chilled-water distribution systems, andmore » boilers. These diagnostic processes can be used to make the commercial buildings more energy efficient. The work described in this report was done as part of a Cooperative Research and Development Agreement (CRADA) between the U.S. Department of Energy's Pacific Northwest National Laboratory (PNNL) and KGS Building LLC (KGS). PNNL and KGS both believe that the widespread adoption of AFDD tools will result in significant reduction to energy and peak energy consumption. The report provides an introduction and summary of the various tasks performed under the CRADA. The CRADA project had three major focus areas: (1) Technical Assistance for Whole Building Energy Diagnostician (WBE) Commercialization, (2) Market Transfer of the Outdoor Air/Economizer Diagnostician (OAE), and (3) Development and Deployment of Automated Diagnostics to Improve Large Commercial Building Operations. PNNL has previously developed two diagnostic tools: (1) whole building energy (WBE) diagnostician and (2) outdoor air/economizer (OAE) diagnostician. WBE diagnostician is currently licensed non-exclusively to one company. As part of this CRADA, PNNL developed implementation documentation and provided technical support to KGS to implement the tool into their software suite, Clockworks. PNNL also provided validation data sets and the WBE software tool to validate the KGS implementation. OAE diagnostician automatically detects and diagnoses problems with outdoor air ventilation and economizer operation for air handling units (AHUs) in commercial buildings using data available from building automation systems (BASs). As part of this CRADA, PNNL developed implementation documentation and provided technical support to KGS to implement the tool into their software suite. PNNL also provided validation data sets and the OAE software tool to validate the KGS implementation. Finally, as part of this CRADA project, PNNL developed new processes to automate parts of the re-tuning process and transfer those process to KGS for integration into their software product. The transfer of DOE-funded technologies will transform the commercial buildings sector by making buildings more energy efficient and also reducing the carbon footprint from the buildings. As part of the CRADA with PNNL, KGS implemented the whole building energy diagnostician, a portion of outdoor air economizer diagnostician and a number of measures that automate the identification of re-tuning measures.« less

  14. Technical Aspects for the Creation of a Multi-Dimensional Land Information System

    NASA Astrophysics Data System (ADS)

    Ioannidis, Charalabos; Potsiou, Chryssy; Soile, Sofia; Verykokou, Styliani; Mourafetis, George; Doulamis, Nikolaos

    2016-06-01

    The complexity of modern urban environments and civil demands for fast, reliable and affordable decision-making requires not only a 3D Land Information System, which tends to replace traditional 2D LIS architectures, but also the need to address the time and scale parameters, that is, the 3D geometry of buildings in various time instances (4th dimension) at various levels of detail (LoDs - 5th dimension). This paper describes and proposes solutions for technical aspects that need to be addressed for the 5D modelling pipeline. Such solutions include the creation of a 3D model, the application of a selective modelling procedure between various time instances and at various LoDs, enriched with cadastral and other spatial data, and a procedural modelling approach for the representation of the inner parts of the buildings. The methodology is based on automatic change detection algorithms for spatial-temporal analysis of the changes that took place in subsequent time periods, using dense image matching and structure from motion algorithms. The selective modelling approach allows a detailed modelling only for the areas where spatial changes are detected. The procedural modelling techniques use programming languages for the textual semantic description of a building; they require the modeller to describe its part-to-whole relationships. Finally, a 5D viewer is developed, in order to tackle existing limitations that accompany the use of global systems, such as the Google Earth or the Google Maps, as visualization software. An application based on the proposed methodology in an urban area is presented and it provides satisfactory results.

  15. Estimation for aerial detection effectiveness with cooperation efficiency factors of early-warning aircraft in early-warning detection SoS under BSC framework

    NASA Astrophysics Data System (ADS)

    Zhu, Feng; Hu, Xiaofeng; He, Xiaoyuan; Guo, Rui; Li, Kaiming; Yang, Lu

    2017-11-01

    In the military field, the performance evaluation of early-warning aircraft deployment or construction is always an important problem needing to be explored. As an effective approach of enterprise management and performance evaluation, Balanced Score Card (BSC) attracts more and more attentions and is studied more and more widely all over the world. It can also bring feasible ideas and technical approaches for studying the issue of the performance evaluation of the deployment or construction of early-warning aircraft which is the important component in early-warning detection system of systems (SoS). Therefore, the deep explored researches are carried out based on the previously research works. On the basis of the characteristics of space exploration and aerial detection effectiveness of early-warning detection SoS and the cardinal principle of BSC are analyzed simply, and the performance evaluation framework of the deployment or construction of early-warning aircraft is given, under this framework, aimed at the evaluation issue of aerial detection effectiveness of early-warning detection SoS with the cooperation efficiency factors of the early-warning aircraft and other land based radars, the evaluation indexes are further designed and the relative evaluation model is further established, especially the evaluation radar chart being also drawn to obtain the evaluation results from a direct sight angle. Finally, some practical computer simulations are launched to prove the validity and feasibility of the research thinking and technologic approaches which are proposed in the paper.

  16. Outlier detection for particle image velocimetry data using a locally estimated noise variance

    NASA Astrophysics Data System (ADS)

    Lee, Yong; Yang, Hua; Yin, ZhouPing

    2017-03-01

    This work describes an adaptive spatial variable threshold outlier detection algorithm for raw gridded particle image velocimetry data using a locally estimated noise variance. This method is an iterative procedure, and each iteration is composed of a reference vector field reconstruction step and an outlier detection step. We construct the reference vector field using a weighted adaptive smoothing method (Garcia 2010 Comput. Stat. Data Anal. 54 1167-78), and the weights are determined in the outlier detection step using a modified outlier detector (Ma et al 2014 IEEE Trans. Image Process. 23 1706-21). A hard decision on the final weights of the iteration can produce outlier labels of the field. The technical contribution is that the spatial variable threshold motivation is embedded in the modified outlier detector with a locally estimated noise variance in an iterative framework for the first time. It turns out that a spatial variable threshold is preferable to a single spatial constant threshold in complicated flows such as vortex flows or turbulent flows. Synthetic cellular vortical flows with simulated scattered or clustered outliers are adopted to evaluate the performance of our proposed method in comparison with popular validation approaches. This method also turns out to be beneficial in a real PIV measurement of turbulent flow. The experimental results demonstrated that the proposed method yields the competitive performance in terms of outlier under-detection count and over-detection count. In addition, the outlier detection method is computational efficient and adaptive, requires no user-defined parameters, and corresponding implementations are also provided in supplementary materials.

  17. RNA-seq: technical variability and sampling

    PubMed Central

    2011-01-01

    Background RNA-seq is revolutionizing the way we study transcriptomes. mRNA can be surveyed without prior knowledge of gene transcripts. Alternative splicing of transcript isoforms and the identification of previously unknown exons are being reported. Initial reports of differences in exon usage, and splicing between samples as well as quantitative differences among samples are beginning to surface. Biological variation has been reported to be larger than technical variation. In addition, technical variation has been reported to be in line with expectations due to random sampling. However, strategies for dealing with technical variation will differ depending on the magnitude. The size of technical variance, and the role of sampling are examined in this manuscript. Results In this study three independent Solexa/Illumina experiments containing technical replicates are analyzed. When coverage is low, large disagreements between technical replicates are apparent. Exon detection between technical replicates is highly variable when the coverage is less than 5 reads per nucleotide and estimates of gene expression are more likely to disagree when coverage is low. Although large disagreements in the estimates of expression are observed at all levels of coverage. Conclusions Technical variability is too high to ignore. Technical variability results in inconsistent detection of exons at low levels of coverage. Further, the estimate of the relative abundance of a transcript can substantially disagree, even when coverage levels are high. This may be due to the low sampling fraction and if so, it will persist as an issue needing to be addressed in experimental design even as the next wave of technology produces larger numbers of reads. We provide practical recommendations for dealing with the technical variability, without dramatic cost increases. PMID:21645359

  18. Chemical Frustration. A Design Principle for the Discovery of New Complex Alloy and Intermetallic Phases, Final Report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Fredrickson, Daniel C

    2015-06-23

    Final technical report for "Chemical Frustration: A Design Principle for the Discovery of New Complex Alloy and Intermetallic Phases" funded by the Office of Science through the Materials Chemistry Program of the Office of Basic Energy Sciences.

  19. Technical support for geopressured-geothermal activities in Louisiana. Final geological report, 1 November 1981-31 October 1982

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Pilger, R.H.

    1984-06-25

    This report contains the component Site-Specific Studies-Geophysics, Diagenesis, Geochemistry. Work for Site-Specific Studies is finished, and the results presented in this report are final. Individual studies have been entered separately into the data base. (ACR)

  20. 78 FR 54566 - Energy Labeling Rule

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-05

    ... FEDERAL TRADE COMMISSION 16 CFR Part 305 RIN 3084-AB03 Energy Labeling Rule AGENCY: Federal Trade Commission. ACTION: Final rule; correction. SUMMARY: The Federal Trade Commission published a final rule on July 23, 2013 revising its Energy Labeling Rule. This document makes a technical correction to the...

  1. Wyoming Deaf/Blind Grant. Final Report.

    ERIC Educational Resources Information Center

    Whitson, Joanne B.

    This final report describes activities and accomplishments of the Wyoming Deaf-Blind Grant, a 3-year federally supported project to identify children who have deaf-blindness and to provide technical assistance in the development of educational services for these children. Major accomplishments of the project included: identification of more…

  2. Suitability of Strain Gage Sensors for Integration into Smart Sport Equipment: A Golf Club Example.

    PubMed

    Umek, Anton; Zhang, Yuan; Tomažič, Sašo; Kos, Anton

    2017-04-21

    Wearable devices and smart sport equipment are being increasingly used in amateur and professional sports. Smart sport equipment employs various sensors for detecting its state and actions. The correct choice of the most appropriate sensor(s) is of paramount importance for efficient and successful operation of sport equipment. When integrated into the sport equipment, ideal sensors are unobstructive, and do not change the functionality of the equipment. The article focuses on experiments for identification and selection of sensors that are suitable for the integration into a golf club with the final goal of their use in real time biofeedback applications. We tested two orthogonally affixed strain gage (SG) sensors, a 3-axis accelerometer, and a 3-axis gyroscope. The strain gage sensors are calibrated and validated in the laboratory environment by a highly accurate Qualisys Track Manager (QTM) optical tracking system. Field test results show that different types of golf swing and improper movement in early phases of golf swing can be detected with strain gage sensors attached to the shaft of the golf club. Thus they are suitable for biofeedback applications to help golfers to learn repetitive golf swings. It is suggested that the use of strain gage sensors can improve the golf swing technical error detection accuracy and that strain gage sensors alone are enough for basic golf swing analysis. Our final goal is to be able to acquire and analyze as many parameters of a smart golf club in real time during the entire duration of the swing. This would give us the ability to design mobile and cloud biofeedback applications with terminal or concurrent feedback that will enable us to speed-up motor skill learning in golf.

  3. Suitability of Strain Gage Sensors for Integration into Smart Sport Equipment: A Golf Club Example

    PubMed Central

    Umek, Anton; Zhang, Yuan; Tomažič, Sašo; Kos, Anton

    2017-01-01

    Wearable devices and smart sport equipment are being increasingly used in amateur and professional sports. Smart sport equipment employs various sensors for detecting its state and actions. The correct choice of the most appropriate sensor(s) is of paramount importance for efficient and successful operation of sport equipment. When integrated into the sport equipment, ideal sensors are unobstructive, and do not change the functionality of the equipment. The article focuses on experiments for identification and selection of sensors that are suitable for the integration into a golf club with the final goal of their use in real time biofeedback applications. We tested two orthogonally affixed strain gage (SG) sensors, a 3-axis accelerometer, and a 3-axis gyroscope. The strain gage sensors are calibrated and validated in the laboratory environment by a highly accurate Qualisys Track Manager (QTM) optical tracking system. Field test results show that different types of golf swing and improper movement in early phases of golf swing can be detected with strain gage sensors attached to the shaft of the golf club. Thus they are suitable for biofeedback applications to help golfers to learn repetitive golf swings. It is suggested that the use of strain gage sensors can improve the golf swing technical error detection accuracy and that strain gage sensors alone are enough for basic golf swing analysis. Our final goal is to be able to acquire and analyze as many parameters of a smart golf club in real time during the entire duration of the swing. This would give us the ability to design mobile and cloud biofeedback applications with terminal or concurrent feedback that will enable us to speed-up motor skill learning in golf. PMID:28430147

  4. Detection of Noble Gas Radionuclides from an Underground Nuclear Explosion During a CTBT On-Site Inspection

    NASA Astrophysics Data System (ADS)

    Carrigan, Charles R.; Sun, Yunwei

    2014-03-01

    The development of a technically sound approach to detecting the subsurface release of noble gas radionuclides is a critical component of the on-site inspection (OSI) protocol under the Comprehensive Nuclear Test Ban Treaty. In this context, we are investigating a variety of technical challenges that have a significant bearing on policy development and technical guidance regarding the detection of noble gases and the creation of a technically justifiable OSI concept of operation. The work focuses on optimizing the ability to capture radioactive noble gases subject to the constraints of possible OSI scenarios. This focus results from recognizing the difficulty of detecting gas releases in geologic environments—a lesson we learned previously from the non-proliferation experiment (NPE). Most of our evaluations of a sampling or transport issue necessarily involve computer simulations. This is partly due to the lack of OSI-relevant field data, such as that provided by the NPE, and partly a result of the ability of computer-based models to test a range of geologic and atmospheric scenarios far beyond what could ever be studied by field experiments, making this approach very highly cost effective. We review some highlights of the transport and sampling issues we have investigated and complete the discussion of these issues with a description of a preliminary design for subsurface sampling that addresses some of the sampling challenges discussed here.

  5. Development of GEM detector for plasma diagnostics application: simulations addressing optimization of its performance

    NASA Astrophysics Data System (ADS)

    Chernyshova, M.; Malinowski, K.; Kowalska-Strzęciwilk, E.; Czarski, T.; Linczuk, P.; Wojeński, A.; Krawczyk, R. D.

    2017-12-01

    The advanced Soft X-ray (SXR) diagnostics setup devoted to studies of the SXR plasma emissivity is at the moment a highly relevant and important for ITER/DEMO application. Especially focusing on the energy range of tungsten emission lines, as plasma contamination by W and its transport in the plasma must be understood and monitored for W plasma-facing material. The Gas Electron Multiplier, with a spatial and energy-resolved photon detecting chamber, based SXR radiation detection system under development by our group may become such a diagnostic setup considering and solving many physical, technical and technological aspects. This work presents the results of simulations aimed to optimize a design of the detector's internal chamber and its performance. The study of the effect of electrodes alignment allowed choosing the gap distances which maximizes electron transmission and choosing the optimal magnitudes of the applied electric fields. Finally, the optimal readout structure design was identified suitable to collect a total formed charge effectively, basing on the range of the simulated electron cloud at the readout plane which was in the order of ~ 2 mm.

  6. Control technology appendices for pollution control technical manuals. Final report, June 1982-February 1983

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    1983-04-01

    The document is one of six technical handbooks prepared by EPA to help government officials granting permits to build synfuels facilities, synfuels process developers, and other interested parties. They provide technical data on waste streams from synfuels facilities and technologies capable of controlling them. Process technologies covered in the manuals include coal gasification, coal liquefaction by direct and idirect processing, and the extraction of oil from shale. The manuals offer no regulatory guidance, allowing the industry flexibility in deciding how best to comply with environmental regulations.

  7. NATO Scientific and Technical Information Service (NSTIS): functional description. Final report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Molholm, K.N.; Blados, W.N.; Bulca, C.

    1987-08-01

    This report provides a functional description of the requirements for a NATO Scientific and Technical Information Service (NSTIS). The user requirements and much of the background information in this report were derived primarily from interviews with more than 60 NATO Headquarters staff members between 2 March and 25 March 1987. In addition, representatives of the Supreme Headquarters Applied Powers Europe (SHAPE) Technical Centre (STC), the Supreme Allied Commander Atlantic (Anti-Submarine Warfare Research) Centre (SACLANTCEN), the NATO Communications and Information Systems Agency (NACISA), The Advisory Group for Aerospace Research and Development (AGARD), the U.S. Defense Technical Information Center (DTIC), and themore » Technical Documentation Center for the Armed Forces in the Netherlands (TDCK), were interviewed, either in person or by telephone.« less

  8. Job Skills Education Program. Final Technical Report.

    ERIC Educational Resources Information Center

    Florida State Univ., Tallahassee. Center for Educational Technology.

    This publication provides materials developed by a project designed to transfer a U.S. Army computer-based basic skills curriculum to applications in the vocational skills development of civilian adults. An executive summary of the final report describes the Job Skills Education Program (JSEP), which teaches academic skills that support vocational…

  9. The Vocational Education Component of the Rhode Island Educational Management Information System.

    ERIC Educational Resources Information Center

    Galamaga, Donald P.; Bartolomeo, Paul A.

    The document describes the implementation (Phase Two) of the Vocational Educational module--one component of an educational management information system. Phase Two entails the technical effort of final system design, final output specifications, edit specifications, system software selection, computer programing, systems documentation and the…

  10. Services for Children with Deaf-Blindness in Louisiana. Final Performance Report.

    ERIC Educational Resources Information Center

    Teddlie, Charles

    This final report describes activities and accomplishments of the Services for Children with Deaf-Blindness project, a 1-year federally supported project in Louisiana to improve identification and curriculum for these children by providing technical assistance and training to parents, school systems, and agency personnel. Project activities…

  11. Evaluating Potential Exposures to Ecological Receptors Due to Transport of Hydrophobic Organic Contaminants in Subsurface Systems (Final Report)

    EPA Science Inventory

    EPA's Ecological Risk Assessment Support Center (ERASC) announced the release of the final report, Evaluating Potential Exposures to Ecological Receptors Due to Transport of Hydrophobic Organic Contaminants in Subsurface Systems. This technical paper recommends several ty...

  12. 78 FR 12955 - Final Requirements, Definitions, and Selection Criteria-Native American Career and Technical...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-26

    ... has established under the Elementary and Secondary Education Act of 1965, as amended (20 U.S.C. 6301..., cooperative education, school-based enterprises, entrepreneurship, community service learning, and job... DEPARTMENT OF EDUCATION 34 CFR Chapter IV [Docket ID ED-2012-OVAE-0053] Final Requirements...

  13. 78 FR 73083 - Compassionate Release

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-05

    ... district in which the inmate was sentenced; and the final decision is subject to the general supervision... rule making a technical change to the regulations on February 28, 2013 (78 FR 13478). We now withdraw... the inmate was sentenced; and (2) clarifying that the final decision is subject to the general...

  14. SIAM Conference on Geometric Design and Computing. Final Technical Report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    None

    2002-03-11

    The SIAM Conference on Geometric Design and Computing attracted 164 domestic and international researchers, from academia, industry, and government. It provided a stimulating forum in which to learn about the latest developments, to discuss exciting new research directions, and to forge stronger ties between theory and applications. Final Report

  15. High/Scope Outreach Project. Final Report. October 1, 1983-September 30, 1984.

    ERIC Educational Resources Information Center

    High/Scope Educational Research Foundation, Ypsilanti, MI.

    The final report reviews accomplishments of an outreach project designed to provide technical assistance and training to early childhood programs for handicapped children. The project features the Cognitively Oriented Preschool Curriculum, a developmental approach based on Piagetian theory and explained to build on the child's accomplishments. A…

  16. Comparison of Final Grades between a Traditional Classroom and Learning Community Classroom at Northeast Wisconsin Technical College.

    ERIC Educational Resources Information Center

    Van Beek, Dianne

    This study examines courses in the marketing program at Northeast Wisconsin Technical College to compare the academic performance of students in traditional and learning community classroom settings. Two sections of students, a traditional 17-week course and a block scheduled 5-week course, served as the sample in the study. The block scheduling…

  17. Classified Information and Technical Libraries. Final Report. Army Technical Library Improvement Studies (ATLIS), Report No. 11.

    ERIC Educational Resources Information Center

    Luger, Herbert P.; Booser, Ronald J.

    A survey of the literature in the last ten years and interviews with library and security personnel indicated: (1)the problems of handling classified information in libraries have been scanted; (2) there is wide divergence in policies and practices of disseminating such materials; (3)interlibrary cooperation with respect to classified holdings is…

  18. Field Testing Competency-Based Vocational Education Student Learning Guides Developed at Ridge Vocational-Technical Center. From August 1, 1981 to June 30, 1982. Final Report.

    ERIC Educational Resources Information Center

    Andreyka, Robert E.

    This project's main objective was to field test competency-based vocational education (CBVE) student learning guides developed during 1979-1981 at Ridge Vocational-Technical Center (RVTC) (Florida). The learning guides were for six programs: clerical occupations, cosmetology, heavy duty truck/bus mechanics, industrial electricity, masonry, and…

  19. 78 FR 17871 - Changes To Implement the Technical Corrections to the Leahy-Smith America Invents Act as to Inter...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-25

    ... rule eliminates the nine-month ``dead zone'' for filing an inter partes review petition challenging a..., section 1(d) of the AIA Technical Corrections Act and this final rule eliminate the nine-month ``dead zone... the nine-month ``dead zone'' as to first-to-invent patents and reissue patents. Costs and Benefits...

  20. Research in Fiber Optics: Implications for Fiber Optics in Vocational-Technical Education. Final Report 1984-85.

    ERIC Educational Resources Information Center

    Bergen County Vocational-Technical High School, Hackensack, NJ.

    This project was conducted to determine the vocational, technical, and scientific skills and knowledge needed to work with the fiber optics applications that are in all areas of technology. A research assistant was hired by the project director to collect data and develop a research base for the project. Information was gathered through a…

  1. The California spotted owl: a technical assessment of its current status

    Treesearch

    Jared Verner; Kevin S. McKelvey; Barry R. Noon; R. J. Gutierrez; Gordon I. Jr. Gould; Thomas W. Beck

    1992-01-01

    This report is based an the Final Repart submitted on May 8, 1992 by the Technical Assessment Team to the interagency Steering Committee for the California Spotted Owl Assessment. The 13 chapters cover the assessment of the current status of the California spotted owl, its biology and habitat use, and forests where the subspecies occurs in the Sierra Nevada and...

  2. Unified Technical Concepts - Phase I. (Modularizing Instructional Materials Using Applications of Technical Concepts). Final Report.

    ERIC Educational Resources Information Center

    Technical Education Research Center, Waco, TX.

    To evolve a new methodology and system for teaching physics to students aspiring to become (or to become more competent as) technicians in a variety of technologies, this research and development effort was initiated. The project's thesis stemmed from a notion that the study of physics would be more accepted and assimilated by students if concepts…

  3. Establishment of the Center for Advanced Separation Technologies

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Christopher E. Hull

    2006-09-30

    This Final Technical Report covers the eight sub-projects awarded in the first year and the five projects awarded in the second year of Cooperative Agreement DE-FC26-01NT41091: Establishment of the Center for Advanced Separation Technologies. This work is summarized in the body of the main report: the individual sub-project Technical Progress Reports are attached as Appendices.

  4. Moka with Ristretto

    DTIC Science & Technology

    2017-11-01

    MOKA WITH RISTRETTO ASSURED INFORMATION SECURITY, INC. NOVEMBER 2017 FINAL TECHNICAL REPORT APPROVED FOR PUBLIC RELEASE; DISTRIBUTION UNLIMITED...STINFO COPY AIR FORCE RESEARCH LABORATORY INFORMATION DIRECTORATE AFRL-RI-RS-TR-2017-223  UNITED STATES AIR FORCE  ROME, NY 13441 AIR FORCE...report is available to the general public, including foreign nations. Copies may be obtained from the Defense Technical Information Center (DTIC

  5. Development of a Screening Methodology for Entry into Medical Technical Training Courses. Final Report for Period October 1975-April 1977.

    ERIC Educational Resources Information Center

    Leisey, Sandra A.; Guinn, Nancy

    At the request of the Air Force School of Aviation Medicine, a project was initiated to evaluate the current screening process used for entry into three medical technical training courses: Aeromedical Specialist, Environmental Health Specialist, and Physiological Training Specialist. A sample of 1,003 students were administered the General…

  6. Summer Institute to Train Data Processing Teachers for the New Oklahoma State-Wide Computer Science System, Phase II. Final Report.

    ERIC Educational Resources Information Center

    Tuttle, Francis

    Twenty-three instructors participated in an 8-week summer institute to develop their technical competency to teach the second year of a 2-year Technical Education Computer Science Program. Instructional material covered the following areas: (1) compiler languages and systems design, (2) cost studies, (3) business organization, (4) advanced…

  7. Technical bases and guidance for the use of composite soil sampling for demonstrating compliance with radiological release criteria

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Vitkus, Timothy J.

    2012-04-24

    This guidance provides information on methodologies and the technical bases that licensees should consider for incorporating composite sampling strategies into final status survey (FSS) plans. In addition, this guidance also includes appropriate uses of composite sampling for generating the data for other decommissioning site investigations such as characterization or other preliminary site investigations.

  8. FIELD CHECK MANUAL FOR LANGUAGE LABORATORIES, A SERIES OF TESTS WHICH A NON-TECHNICAL PERSON CAN CONDUCT TO VERIFY SPECIFICATIONS.

    ERIC Educational Resources Information Center

    GRITTNER, FRANK; PAVLAT, RUSSELL

    IN ORDER TO ASSIST NON-TECHNICAL PEOPLE IN SCHOOLS TO CONDUCT A FIELD CHECK OF LANGUAGE LABORATORY EQUIPMENT BEFORE THEY MAKE FINAL PAYMENTS, THIS MANUAL OFFERS CRITERIA, TESTS, AND METHODS OF SCORING THE QUALITY OF THE EQUIPMENT. CHECKLISTS ARE PROVIDED FOR EVALUATING CONSOLE FUNCTIONS, TAPE RECORDERS, AMPLIFIERS, SOUND QUALITY (INCLUDING…

  9. Organic and Hybrid Organic Solid-State Photovoltaic Materials and Devices

    DTIC Science & Technology

    2014-03-06

    Microscopy Research, 2012, 7, 158-169. Organic photovoltaic materials, hybrid organic devices, solar cells 6 1 FINAL TECHNICAL REPORT 1... hybrids have potential applications in solar cells and may thus provide mobile energy sources for aircraft and soldier technologies. Modeling and...modeling and simulation developed in this project are encouraging further development. 2. Technical Activities Hybrid organic solar cells are an

  10. Space station automation study: Autonomous systems and assembly, volume 2

    NASA Technical Reports Server (NTRS)

    Bradford, K. Z.

    1984-01-01

    This final report, prepared by Martin Marietta Denver Aerospace, provides the technical results of their input to the Space Station Automation Study, the purpose of which is to develop informed technical guidance in the use of autonomous systems to implement space station functions, many of which can be programmed in advance and are well suited for automated systems.

  11. Novel Hierarchical Fall Detection Algorithm Using a Multiphase Fall Model.

    PubMed

    Hsieh, Chia-Yeh; Liu, Kai-Chun; Huang, Chih-Ning; Chu, Woei-Chyn; Chan, Chia-Tai

    2017-02-08

    Falls are the primary cause of accidents for the elderly in the living environment. Reducing hazards in the living environment and performing exercises for training balance and muscles are the common strategies for fall prevention. However, falls cannot be avoided completely; fall detection provides an alarm that can decrease injuries or death caused by the lack of rescue. The automatic fall detection system has opportunities to provide real-time emergency alarms for improving the safety and quality of home healthcare services. Two common technical challenges are also tackled in order to provide a reliable fall detection algorithm, including variability and ambiguity. We propose a novel hierarchical fall detection algorithm involving threshold-based and knowledge-based approaches to detect a fall event. The threshold-based approach efficiently supports the detection and identification of fall events from continuous sensor data. A multiphase fall model is utilized, including free fall, impact, and rest phases for the knowledge-based approach, which identifies fall events and has the potential to deal with the aforementioned technical challenges of a fall detection system. Seven kinds of falls and seven types of daily activities arranged in an experiment are used to explore the performance of the proposed fall detection algorithm. The overall performances of the sensitivity, specificity, precision, and accuracy using a knowledge-based algorithm are 99.79%, 98.74%, 99.05% and 99.33%, respectively. The results show that the proposed novel hierarchical fall detection algorithm can cope with the variability and ambiguity of the technical challenges and fulfill the reliability, adaptability, and flexibility requirements of an automatic fall detection system with respect to the individual differences.

  12. Novel Hierarchical Fall Detection Algorithm Using a Multiphase Fall Model

    PubMed Central

    Hsieh, Chia-Yeh; Liu, Kai-Chun; Huang, Chih-Ning; Chu, Woei-Chyn; Chan, Chia-Tai

    2017-01-01

    Falls are the primary cause of accidents for the elderly in the living environment. Reducing hazards in the living environment and performing exercises for training balance and muscles are the common strategies for fall prevention. However, falls cannot be avoided completely; fall detection provides an alarm that can decrease injuries or death caused by the lack of rescue. The automatic fall detection system has opportunities to provide real-time emergency alarms for improving the safety and quality of home healthcare services. Two common technical challenges are also tackled in order to provide a reliable fall detection algorithm, including variability and ambiguity. We propose a novel hierarchical fall detection algorithm involving threshold-based and knowledge-based approaches to detect a fall event. The threshold-based approach efficiently supports the detection and identification of fall events from continuous sensor data. A multiphase fall model is utilized, including free fall, impact, and rest phases for the knowledge-based approach, which identifies fall events and has the potential to deal with the aforementioned technical challenges of a fall detection system. Seven kinds of falls and seven types of daily activities arranged in an experiment are used to explore the performance of the proposed fall detection algorithm. The overall performances of the sensitivity, specificity, precision, and accuracy using a knowledge-based algorithm are 99.79%, 98.74%, 99.05% and 99.33%, respectively. The results show that the proposed novel hierarchical fall detection algorithm can cope with the variability and ambiguity of the technical challenges and fulfill the reliability, adaptability, and flexibility requirements of an automatic fall detection system with respect to the individual differences. PMID:28208694

  13. NESC Independent Review of the Mars Reconnaissance Orbiter (MRO) Contamination Thermal/Vacuum (T/V) Anomaly Technical Consultation Report

    NASA Technical Reports Server (NTRS)

    Sutter, James K.; Leidecker, Henning W.; Panda, Binayak; Piascik, Robert S.; Muirhead, Brian K.; Peeler, Debra

    2009-01-01

    The NESC eras requested by the NASA Jet Propulsion Laboratory (JPL) to conduct an independent review of the Mars Reconnaissance Orbiter (MRO) Thermal/Vacuum (T/V) Anomaly Assessment. Because the anomaly resulted in the surface contamination of the MRO, selected members of the Materials Super Problem Resolution Team (SPRT) and the NASA technical community having technical expertise relative to contamination issues were chosen for the independent review. The consultation consisted of a review of the MRO Project's reported response to the assessment findings, a detailed review of JPL technical assessment final report, and detailed discussions with the JPL assessment team relative to their findings.

  14. 76 FR 73727 - Biweekly Notice; Applications and Amendments to Facility Operating Licenses Involving No...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-29

    ... Detection Instrumentation,'' to define a new time limit for restoring inoperable RCS leakage detection... Specifications Section 3.4.15 regarding reactor coolant leakage detection instrumentation to be consistent with... amendments revised the Technical Specifications (TSs) ``RCS [reactor coolant system] Leakage Detection...

  15. Final Technical Report for DE-FG02-98ER45737

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ade, Harald W.

    This document represents the cumulative, final technical report for Grant No. DE-FG02- 98ER45737, the title of which has changed with each funding period, but the research pursued is within a coherent overall theme of methods and technique developments that exploit contrast at the carbon absorption edge to characterize complex organic materials and the use of these synchrotron radiation-based methods for important research challenges in polymer physics and Materials Science. The last three funding periods focused on organic devices and in particular organic solar cells (OSCs), owing to their extra-ordinarily complex morphology, yet high potential as a cheap and printable power-conversionmore » technology.« less

  16. Collaborative study on the effect of grinding on the detection of bones from processed animal proteins in feed by light microscopy.

    PubMed

    Veys, Pascal; Planchon, Viviane; Colbert, Ruairi; Cruz, Clara; Frick, Geneviève; Ioannou, Ioannis; Marchis, Daniela; Nordkvist, Erik; Paradies-Severin, Inge; Pohto, Arja; Weiss, Roland; Baeten, Vincent; Berben, Gilbert

    2017-08-01

    Bone fragments are essential structures for the detection of processed animal proteins (PAPs) in feed by light microscopy for official controls according to Annex VI of European Union Regulation EC/152/2009. The preparation of samples submitted for analysis requires a grinding step to make them suitable for microscopic slide preparation and observation. However, there are no technical guidelines set down for this step despite the fact that it can lead to an increase in bone numbers due to fragmentation. This was demonstrated by an in-house study carried out by the Irish National Reference Laboratory (NRL) for animal protein detection. The present collaborative study investigated the possible effects of three different grinding conditions on the final result for a feed adulterated with 0.05 and 0.01% (w/w) of PAP. The microscopic analysis either combined or not with an Alizarin Red staining was carried out by 10 different laboratories. The results demonstrated that although a large variation in the numbers of bone fragments was noted, five of the six different grinding/staining combinations applied at two levels of PAP adulteration did not significantly (at p = 0.05) differ from one another. The only exception occurred when grinding the feed containing 0.05% of PAP with a rotor mill equipped with a 0.5-mm sieve and combined with a staining which resulted in a greater number of bone fragments by forced fragmentation. Overall, the impact of the grinding/staining combinations on the final results was shown to be negligible when considering the regulatory limit of detection (LOD) requirement for the method and the current rules of implementation of the light microscopic method. From a total of 180 analyses carried out on the feed matrix containing 0.05% of PAP no false-negative result was observed, and at a level of 0.01% PAP only 10 false-negative results occurred.

  17. A Review of Organic and Inorganic Biomaterials for Neural Interfaces

    PubMed Central

    Fattahi, Pouria; Yang, Guang; Kim, Gloria

    2015-01-01

    Recent advances in nanotechnology have generated wide interest in applying nanomaterials for neural prostheses. An ideal neural interface should create seamless integration into the nervous system and performs reliably for long periods of time. As a result, many nanoscale materials not originally developed for neural interfaces become attractive candidates to detect neural signals and stimulate neurons. In this comprehensive review, an overview of state-of-the-art microelectrode technologies provided first, with focus on the material properties of these microdevices. The advancements in electro active nanomaterials are then reviewed, including conducting polymers, carbon nanotubes, graphene, silicon nanowires, and hybrid organic-inorganic nanomaterials, for neural recording, stimulation, and growth. Finally, technical and scientific challenges are discussed regarding biocompatibility, mechanical mismatch, and electrical properties faced by these nanomaterials for the development of long-lasting functional neural interfaces. PMID:24677434

  18. A review of organic and inorganic biomaterials for neural interfaces.

    PubMed

    Fattahi, Pouria; Yang, Guang; Kim, Gloria; Abidian, Mohammad Reza

    2014-03-26

    Recent advances in nanotechnology have generated wide interest in applying nanomaterials for neural prostheses. An ideal neural interface should create seamless integration into the nervous system and performs reliably for long periods of time. As a result, many nanoscale materials not originally developed for neural interfaces become attractive candidates to detect neural signals and stimulate neurons. In this comprehensive review, an overview of state-of-the-art microelectrode technologies provided fi rst, with focus on the material properties of these microdevices. The advancements in electro active nanomaterials are then reviewed, including conducting polymers, carbon nanotubes, graphene, silicon nanowires, and hybrid organic-inorganic nanomaterials, for neural recording, stimulation, and growth. Finally, technical and scientific challenges are discussed regarding biocompatibility, mechanical mismatch, and electrical properties faced by these nanomaterials for the development of long-lasting functional neural interfaces.

  19. Applications of Aptamers as Sensors

    NASA Astrophysics Data System (ADS)

    Cho, Eun Jeong; Lee, Joo-Woon; Ellington, Andrew D.

    2009-07-01

    Aptamers are ligand-binding nucleic acids whose affinities and selectivities can rival those of antibodies. They have been adapted to analytical applications not only as alternatives to antibodies, but as unique reagents in their own right. In particular, aptamers can be readily site-specifically modified during chemical or enzymatic synthesis to incorporate particular reporters, linkers, or other moieties. Also, aptamer secondary structures can be engineered to undergo analyte-dependent conformational changes, which, in concert with the ability to specifically place chemical agents, opens up a wealth of possible signal transduction schemas, irrespective of whether the detection modality is optical, electrochemical, or mass based. Finally, because aptamers are nucleic acids, they are readily adapted to sequence- (and hence signal-) amplification methods. However, application of aptamers without a basic knowledge of their biochemistry or technical requirements can cause serious analytical difficulties.

  20. Technical Insights into Highly Sensitive Isolation and Molecular Characterization of Fixed and Live Circulating Tumor Cells for Early Detection of Tumor Invasion

    PubMed Central

    Laget, Sophie; Dhingra, Dalia M.; BenMohamed, Fatima; Capiod, Thierry; Osteras, Magne; Farinelli, Laurent; Jackson, Stephen; Paterlini-Bréchot, Patrizia

    2017-01-01

    Circulating Tumor Cells (CTC) and Circulating Tumor Microemboli (CTM) are Circulating Rare Cells (CRC) which herald tumor invasion and are expected to provide an opportunity to improve the management of cancer patients. An unsolved technical issue in the CTC field is how to obtain highly sensitive and unbiased collection of these fragile and heterogeneous cells, in both live and fixed form, for their molecular study when they are extremely rare, particularly at the beginning of the invasion process. We report on a new protocol to enrich from blood live CTC using ISET® (Isolation by SizE of Tumor/Trophoblastic Cells), an open system originally developed for marker-independent isolation of fixed tumor cells. We have assessed the impact of our new enrichment method on live tumor cells antigen expression, cytoskeleton structure, cell viability and ability to expand in culture. We have also explored the ISET® in vitro performance to collect intact fixed and live cancer cells by using spiking analyses with extremely low number of fluorescent cultured cells. We describe results consistently showing the feasibility of isolating fixed and live tumor cells with a Lower Limit of Detection (LLOD) of one cancer cell per 10 mL of blood and a sensitivity at LLOD ranging from 83 to 100%. This very high sensitivity threshold can be maintained when plasma is collected before tumor cells isolation. Finally, we have performed a comparative next generation sequencing (NGS) analysis of tumor cells before and after isolation from blood and culture. We established the feasibility of NGS analysis of single live and fixed tumor cells enriched from blood by our system. This study provides new protocols for detection and characterization of CTC collected from blood at the very early steps of tumor invasion. PMID:28060956

  1. Environmental information acquisition and maintenance techniques: reference guide. Final report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Riggins, R.E.; Young, V.T.; Goran, W.D.

    1980-08-01

    This report provides a guide to techniques for collecting, using and maintaining data about each of the 13 environmental technical specialties in the Environmental Impact Computer System (EICS). The technical specialties are: (1) ecology, (2) environmental health, (3) air, (4) surface water, (5) ground water, (6) sociology, (7) economics, (8) earth science, (9) land use, (10) noise, (11) transportation, (12) aesthetics, and (13) energy and resource conservation. Acquisition techniques are classified by the following general categories: (1) secondary data, (2) remote sensing, (3) mathematical modeling, (4) field work, (5) mapping/maps and (6) expert opinion. A matrix identifies the most appropriatemore » techniques for collecting information on the EICS technical specialties. After selecting a method, the user may read an abstract of the report explaining that technique, and may also wish to obtain the original document for detailed information about applying the technique. Finally, this report offers guidelines on storing environmental information for future use, and on presenting that information effectively in environmental documents.« less

  2. NEET-AMM Final Technical Report on Laser Direct Manufacturing (LDM) for Nuclear Power Components

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Anderson, Scott; Baca, Georgina; O'Connor, Michael

    2015-12-31

    Final technical report summarizes the program progress and technical accomplishments of the Laser Direct Manufacturing (LDM) for Nuclear Power Components project. A series of experiments varying build process parameters (scan speed and laser power) were conducted at the outset to establish the optimal build conditions for each of the alloys. Fabrication was completed in collaboration with Quad City Manufacturing Laboratory (QCML). The density of all sample specimens was measured and compared to literature values. Optimal build process conditions giving fabricated part densities close to literature values were chosen for making mechanical test coupons. Test coupons whose principal axis is onmore » the x-y plane (perpendicular to build direction) and on the z plane (parallel to build direction) were built and tested as part of the experimental build matrix to understand the impact of the anisotropic nature of the process.. Investigations are described 316L SS, Inconel 600, 718 and 800 and oxide dispersion strengthed 316L SS (Yttria) alloys.« less

  3. An approach to developing independent learning and non-technical skills amongst final year mining engineering students

    NASA Astrophysics Data System (ADS)

    Knobbs, C. G.; Grayson, D. J.

    2012-06-01

    There is mounting evidence to show that engineers need more than technical skills to succeed in industry. This paper describes a curriculum innovation in which so-called 'soft' skills, specifically inter-personal and intra-personal skills, were integrated into a final year mining engineering course. The instructional approach was designed to promote independent learning and to develop non-technical skills, essential for students on the threshold of becoming practising engineers. Three psychometric tests were administered at the beginning of the course to make students aware of their own and their classmates' characteristics. Substantial prescribed reading assignments preceded weekly group discussions. Several projects during the course required team work skills and application of content knowledge to real-world contexts. Results obtained from students' reflection papers, assignments related to 'soft' skills and end of course evaluations suggest that students' appreciation of the need for these skills, as well as their own perceived competence, increased during the course. Their ability to function as independent learners also increased.

  4. Identification of usual interstitial pneumonia pattern using RNA-Seq and machine learning: challenges and solutions.

    PubMed

    Choi, Yoonha; Liu, Tiffany Ting; Pankratz, Daniel G; Colby, Thomas V; Barth, Neil M; Lynch, David A; Walsh, P Sean; Raghu, Ganesh; Kennedy, Giulia C; Huang, Jing

    2018-05-09

    We developed a classifier using RNA sequencing data that identifies the usual interstitial pneumonia (UIP) pattern for the diagnosis of idiopathic pulmonary fibrosis. We addressed significant challenges, including limited sample size, biological and technical sample heterogeneity, and reagent and assay batch effects. We identified inter- and intra-patient heterogeneity, particularly within the non-UIP group. The models classified UIP on transbronchial biopsy samples with a receiver-operating characteristic area under the curve of ~ 0.9 in cross-validation. Using in silico mixed samples in training, we prospectively defined a decision boundary to optimize specificity at ≥85%. The penalized logistic regression model showed greater reproducibility across technical replicates and was chosen as the final model. The final model showed sensitivity of 70% and specificity of 88% in the test set. We demonstrated that the suggested methodologies appropriately addressed challenges of the sample size, disease heterogeneity and technical batch effects and developed a highly accurate and robust classifier leveraging RNA sequencing for the classification of UIP.

  5. Key team physical and technical performance indicators indicative of team quality in the soccer Chinese super league.

    PubMed

    Yang, Gai; Leicht, Anthony S; Lago, Carlos; Gómez, Miguel-Ángel

    2018-01-01

    The aim of this study was to identify the key physical and technical performance variables related to team quality in the Chinese Super League (CSL). Teams' performance variables were collected from 240 matches and analysed via analysis of variance between end-of-season-ranked groups and multinomial logistic regression. Significant physical performance differences between groups were identified for sprinting (top-ranked group vs. upper-middle-ranked group) and total distance covered without possession (upper and upper-middle-ranked groups and lower-ranked group). For technical performance, teams in the top-ranked group exhibited a significantly greater amount of possession in opponent's half, number of entry passes in the final 1/3 of the field and the Penalty Area, and 50-50 challenges than lower-ranked teams. Finally, time of possession increased the probability of a win compared with a draw. The current study identified key performance indicators that differentiated end-season team quality within the CSL.

  6. Analysis and Characterization of Polychlorinated Hydroxybornanes as Metabolites of Toxaphene Using a Polar Bear Model.

    PubMed

    Reger, Lea; Gallistl, Christoph; Skírnisson, Karl; Vetter, Walter

    2017-08-01

    Abiotic and biotic transformation of toxaphene (camphechlor) results in the selective enrichment of recalcitrant congeners while other, less persistent compounds of technical toxaphene (CTTs) are degraded. Until now, there has been little knowledge on oxidation transformation of toxaphene. For instance, the existence of hydroxylated CTTs (OH-CTTs) in authentic environmental and food samples has not been proven. For this reason, we synthesized a mixture consisting of tetra- to heptachlorinated OH-CTTs and simplified it by countercurrent chromatography (CCC). Thus, 227 OH-CTTs were detected in the CCC fractions (12 tetra-, 117 penta-, 81 hexa-, and 17 heptachlorinated OH-CTTs), which was >50% more than detected before the fractionation. One CCC fraction consisting of only 18 OH-CTTs was used to develop a sample cleanup method which aimed to remove CTTs, isobaric PCBs, and sample matrix. The final cleanup procedure consisted of (i) gel permeation chromatography (GPC) and adsorption chromatography using (ii) deactivated and (iii) activated silica gel. Hence, up to 320 and 4350 μg/kg lipid weight of octa- and nonachlorinated CTTs were detected in four liver samples and adipose tissue of polar bears, respectively. Furthermore, the presence of one hexachlorinated OH-CTT isomer could be verified in the samples, which was about 1% of the octachlorinated CTTs determined in the liver samples.

  7. Intracellular in situ labeling of TiO 2 nanoparticles for fluorescence microscopy detection

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Brown, Koshonna; Thurn, Ted; Xin, Lun

    Titanium dioxide (TiO 2) nanoparticles are produced for many different purposes, including development of therapeutic and diagnostic nanoparticles for cancer detection and treatment, drug delivery, induction of DNA double-strand breaks, and imaging of specific cells and subcellular structures. Currently, the use of optical microscopy, an imaging technique most accessible to biology and medical pathology, to detect TiO 2 nanoparticles in cells and tissues ex vivo is limited with low detection limits, while more sensitive imaging methods (transmission electron microscopy, X-ray fluorescence microscopy, etc.) have low throughput and technical and operational complications. In this paper, we describe two in situ posttreatmentmore » labeling approaches to stain TiO 2 nanoparticles taken up by the cells. The first approach utilizes fluorescent biotin and fluorescent streptavidin to label the nanoparticles before and after cellular uptake; the second approach is based on the copper-catalyzed azide-alkyne cycloaddition, the so-called Click chemistry, for labeling and detection of azide-conjugated TiO 2 nanoparticles with alkyneconjugated fluorescent dyes such as Alexa Fluor 488. To confirm that optical fluorescence signals of these nanoparticles match the distribution of the Ti element, we used synchrotron X-ray fluorescence microscopy (XFM) at the Advanced Photon Source at Argonne National Laboratory. Titanium-specific XFM showed excellent overlap with the location of optical fluorescence detected by confocal microscopy. Finally and therefore, future experiments with TiO 2 nanoparticles may safely rely on confocal microscopy after in situ nanoparticle labeling using approaches described here.« less

  8. Intracellular in situ labeling of TiO 2 nanoparticles for fluorescence microscopy detection

    DOE PAGES

    Brown, Koshonna; Thurn, Ted; Xin, Lun; ...

    2017-07-19

    Titanium dioxide (TiO 2) nanoparticles are produced for many different purposes, including development of therapeutic and diagnostic nanoparticles for cancer detection and treatment, drug delivery, induction of DNA double-strand breaks, and imaging of specific cells and subcellular structures. Currently, the use of optical microscopy, an imaging technique most accessible to biology and medical pathology, to detect TiO 2 nanoparticles in cells and tissues ex vivo is limited with low detection limits, while more sensitive imaging methods (transmission electron microscopy, X-ray fluorescence microscopy, etc.) have low throughput and technical and operational complications. In this paper, we describe two in situ posttreatmentmore » labeling approaches to stain TiO 2 nanoparticles taken up by the cells. The first approach utilizes fluorescent biotin and fluorescent streptavidin to label the nanoparticles before and after cellular uptake; the second approach is based on the copper-catalyzed azide-alkyne cycloaddition, the so-called Click chemistry, for labeling and detection of azide-conjugated TiO 2 nanoparticles with alkyneconjugated fluorescent dyes such as Alexa Fluor 488. To confirm that optical fluorescence signals of these nanoparticles match the distribution of the Ti element, we used synchrotron X-ray fluorescence microscopy (XFM) at the Advanced Photon Source at Argonne National Laboratory. Titanium-specific XFM showed excellent overlap with the location of optical fluorescence detected by confocal microscopy. Finally and therefore, future experiments with TiO 2 nanoparticles may safely rely on confocal microscopy after in situ nanoparticle labeling using approaches described here.« less

  9. [NASA/DOD Aerospace Knowledge Diffusion Research Project. Report 1, part 1:] Technical communications in aeronautics: Results of an exploratory study

    NASA Technical Reports Server (NTRS)

    Pinelli, Thomas E.; Glassman, Myron; Oliu, Walter E.; Barclay, Rebecca O.

    1989-01-01

    A study was undertaken that explored several aspects of technical communications in aeronautics. The study, which utilized survey research in the form of a self-administered questionnaire, was sent to 2,000 randomly selected members of the American Institute of Aeronautics and Astronautics. Six hundred and six usable questionnaires (30.3 percent) were received by the established cut off date. The study had five objectives. The first was to solicit the opinions of aeronautical engineers and scientists regarding the importance of technical communications to their profession; second, to determine their use and production of technical communications; third, to seek their views on the content of an undergraduate course in technical communications; fourth, to determine their use of libraries/technical information centers; and finally, to determine the use and importance of computer and information technology to them. The findings add considerable information to the knowledge of technical communications practices among aeronautical engineers and scientists and reinforce some of the conventional wisdom about technical communications and question other widely-held notions.

  10. The Assessment of Liver Reserve Function by Spectrophotometry based on Determination of Phenacetin and Paracetamol.

    PubMed

    Ren, Rui; Ma, Yongmei; Ma, Wanshan; Lu, Sumei

    2015-01-01

    To establish a technical system for assessing liver reserve function based on spectrophotometry by detection of phenacetin and paracetamol in blood samples. Taking detected contents of phenacetin and paracetamol by high performance liquid chromatography (HPLC) as standard, which was proved to be able to detect drug concentrations with high resolution and accuracy, we established a technical system based on the spectrophotometric technique to assay phenacetin and paracetamol, including the color system, the maximum absorption wavelength, the influence factors of color system, and the optimal conditions for hydrolysis. Then we verified our established system compared with that under HPLC by recovery test. This study established a technical system to detect phenacetin and paracetamol in blood samples using spectrophotometry. Mainly, 3 mol/L hydrochloric acid (HCl) was added to samples for hydrolysis for 30 minutes, then, adding 0.02% 1,2-naphthoquinone-4-sulfonate (NQS), 1% cetyltrimethyl ammonium bromide (CTA) and 2% sodium hydroxide (or 3% sodium carbonate) (ratio of 1:6:1:2 or 3), and the absorbance was measured at 500 nm and 570 nm to calculate their concentrations. Using an established spectrophotometric system to detect phenacetin and paracetamol in blood samples could assess liver reserve function, which was proved comparable with HPLC in resolution and repeatability.

  11. Ultrasonic Imaging and Automated Flaw Detection System

    DTIC Science & Technology

    1986-03-01

    176 007 !----------------------------- DS 176 500 ------------------------- ! STEPPER MOOC TOR MAP 176 ~ ~ IGR 509------------------- I I28 * 4W...ATTN: SMCAR-CCB-R 2 -R (ELLEN FOGARTY) 1 -RA 1 -RM 1 -RP I -RT TECHNICAL LIBRARY 5 ATTN: SMCAR-CCB-TL TECHNICAL PUBLICATIONS & EDITING UNIT 2 ATTN...WEAPONS CTR ATTN: TECHNICAL LIBRARY CODE X212 DAIILGREN, VA 22448 ’.1 -_ NOTE: PLEASE NOTIFY COMMANDER, ARMAMENT RESEARCH AND DEVELOPMENT CENTER, US

  12. Feasibility of Computer Processing of Technical Information on the Design of Instructional Systems. Final Report for the Period 1 July 1972 through 31 March 1973.

    ERIC Educational Resources Information Center

    Scheffler, F. L.; And Others

    A feasibility study examined the capability of a computer-based system's handling of technical information pertinent to the design of instructional systems. Structured interviews were held to assess the information needs of both researchers and practitioners and an investigation was conducted of 10 computer-based information storage and retrieval…

  13. Task Force on the Role of General Education in Associate Science Degree Programs. Final Report and Recommendations.

    ERIC Educational Resources Information Center

    Weyers, Lori; Langerman, Philip

    In 1989-90, the General Education Task Force of the Wisconsin Technical College System (WTCS) was convened to determine the role of the general education curriculum in the attainment of skills that enhance the likelihood of success among technical college graduates in their careers, homes and communities. The Task Force consisted of at least one…

  14. Adlai E. Stevenson High School, Bilingual Academic and Technical Education for Youth Program. O.E.E. Evaluation Report, 1982-1983.

    ERIC Educational Resources Information Center

    Keyes, Jose Luis; Collins, Carla

    The Bilingual Academic and Technical Education for Youth (BATEY) Program completed its third and final year of funding at Adlai E. Stevenson High School, Bronx, New York. In 1982-83, the program offered bilingual instruction and support services to approximately 300 Hispanic students of limited English proficiency in grades 9-12. Although the…

  15. 77 FR 57186 - Technical Report on Fatality Risk, Mass, and Footprint of Model Year 2000-2007 Passenger Cars and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-17

    ...-0152] Technical Report on Fatality Risk, Mass, and Footprint of Model Year 2000-2007 Passenger Cars and..., and Footprint in Model Year 2000-2007 Passenger Cars and LTVs--Final Report. DATES: Comments must be... comprised MY 2000-2007 cars and LTVs in CY 2002-2008 crashes. Fatality rates were derived from FARS data, 13...

  16. A Planning Study for the Conversion of Recorded Books and Magazines from Rigid Discs to Cassettes and Flexible Discs. Final Report.

    ERIC Educational Resources Information Center

    Innovative Systems Research, Inc., Pennsauken, NJ.

    Twelve different conversion plans were delineated and evaluated in the performance of this study effort. An indepth technical, financial, and cost/benefit analysis was included. One plan was determined to be distinctively more cost-effective than any of the other plans because it provided a technically feasible system that assured the maximum…

  17. Technical Feasibility Study of an Effective Low-Toxicity Obscurant Material

    DTIC Science & Technology

    2012-08-01

    2. REPORT TYPE FINAL 3. DATES COVERED (From - To) 04/2011 – 07/2012 4 . TITLE AND SUBTITLE 5a. CONTRACT NUMBER W912HQ-11-C-0034 Technical...6 4 Work Package 3 – Laboratory-scale tests...chemistry to sea-salt aerosol. 4 The major component of sea-salt is sodium chloride. Sodium chloride can be very simply generated by the combustion

  18. The Attitudes of the Final Students of Technical Education Faculty at Kocaeli University towards Their Faculty's Closing Down

    ERIC Educational Resources Information Center

    Ira, Nejat

    2015-01-01

    The purpose of the research is to identify the attitudes of the students at Kocaeli University towards closing down of Technical Education Faculty. These faculties were decided to be closed down in 2009. Since then, both the students and the instructors have been in ambiguity about their future careers. This situation has also affected them…

  19. A Proposed Modified Technical Order System and Its Impact on Maintenance, Personnel and Training. Final Report for Period December 1974-September 1975.

    ERIC Educational Resources Information Center

    Foley, John P., Jr.

    The document presents immediate and long range plans for the systematic injection of Symbolic Integrated Maintenance Systems (SIMS) and Fully Proceduralized Job Performance Aids (FPJPA) materials into the current technical order system and the inclusion of job-oriented training matched to FPJPA into the training system of the Air Force. The text…

  20. Advanced Authoring Technologies, Capabilities and Opportunities (Technologies avancees d’authoring, possibilites et opportunites)

    DTIC Science & Technology

    2011-02-01

    NORTH ATLANTIC TREATY ORGANISATION RESEARCH AND TECHNOLOGY ORGANISATION AC/323(HFM-129)TP/349 www.rto.nato.int RTO TECHNICAL REPORT TR...Final Report of Task Group HFM-129. Published February 2011 Distribution and Availability on Back Cover...NORTH ATLANTIC TREATY ORGANISATION RESEARCH AND TECHNOLOGY ORGANISATION AC/323(HFM-129)TP/349 www.rto.nato.int RTO TECHNICAL REPORT TR-HFM

  1. The Ability of Standardized Test Instruments to Differentiate Membership in Different Vocational-Technical Curricula. Project MINI-SCORE, Final Technical Report.

    ERIC Educational Resources Information Center

    Pucel, David J.; And Others

    Using post-secondary vocational education students as the populations, these two sub-studies of the Project MINI-SCORE sought to determine the extent to which pre-enrollment standardized test data can be used to predict vocational success. For the purpose of the study, vocational success was defined either as successful graduation or successful…

  2. Learning from Experience Case Studies of the Hyper-X Project

    NASA Technical Reports Server (NTRS)

    Peebles, Curtis

    2009-01-01

    The Hyper-X project (X-43A) provides a number of "lessons learned" which can be applied to other aerospace project. The specific areas examined were the selection of the goals of the Hyper-X. How the technical unknowns and assumptions were handled. The final lesson was the ambiguous nature of risk assessment, and how trying to remove a technical unknown can have unintended consequences.

  3. Helicopter Dynamic Performance Program. Volume 2. User’s Manual

    DTIC Science & Technology

    1980-07-01

    Technologies Corporation Stratford, Connecticut 06602 July 1980 Final Report / • ., . Approved for public release; I distribution unlimited. ; A - Prepared...for : APPLIED TECHNOLOGY LABORATORY U. S. ARMY RESEARCH AND TECHNOLOGY LABORATORIES (AVRADCOM) Fort Eustis, Va. 23604 80 8 27 D APPLIED TECHNOLOGY ... Technology Division. Technic31 review of this report was also pro- vided by Messrs. W_ A. Pleasants of Design Integration and Analysis Technical Area

  4. A Study of Placing Army Requirements on Contract

    DTIC Science & Technology

    2016-04-01

    perhaps being unable to control the external environment, has management authority over business and technical aspects of a specific program. The PM...research is the last element of the planning phase addressing both business and technical considerations. The acquisition team equips themselves with...report is the final product utilizing documented findings and supports the business strategy (DoD, Guidebook for the Acquisition of Services, 2011

  5. Comparison of Effectiveness of Collaborative Learning Methods and Traditional Methods in Physics Classes at Northern Maine Technical College.

    ERIC Educational Resources Information Center

    Overlock, Terrence H., Sr.

    To determine the effect of collaborative learning methods on the success rate of physics students at Northern Maine Technical College (NMTC), a study was undertaken to compare the mean final exam scores of a students in a physics course taught by traditional lecture/lab methods to those in a group taught by collaborative techniques. The…

  6. Impact of Entrepreneurship Education on the Entrepreneurial Intentions of Students in Technical and Vocational Education and Training Institutions (TVET) in Malaysia

    ERIC Educational Resources Information Center

    Ibrahim, Wan Nur Azlina; Bakar, Ab. Rahim; Asimiran, Soaib; Mohamed, Shamsiah; Zakaria, Noor Syamilah

    2015-01-01

    The purpose of this study was to determine the entrepreneurial intention level of vocational and technical students in Malaysia. A total of 289 final year students who were enrolled at two different TVET institutions (community colleges and National Youth and Skills Institutes) were chosen to participate in the study. The findings indicated that…

  7. A Pilot Research Project to Determine the Feasibility of Developing Health Related Occupations Curricula at Nicolet College and Technical Institute. Final Report.

    ERIC Educational Resources Information Center

    Maney, Thomas J.; Boyd, Linda

    Personal interviews with each employer of health care workers in the Nicolet Vocational, Technical and Adult Education (VTAE) District were conducted to determine: (1) the extent of need for trained health occupations personnel in the district; (2) the projected need for such personnel in the future; (3) which specific health occupations currently…

  8. Final Report of Technical Assistance Provided to Guarantee Agencies with Recommendations for Further Improving Program Performance.

    ERIC Educational Resources Information Center

    Touche Ross and Co., Washington, DC.

    Technical assistance provided to loan guarantee agencies by Touche Ross and Co. under contract to the U.S. Office of Education (OE) is described. Objectives of the report are: to summarize the work performed and the results of each of the projects that were conducted; to describe certain prototype systems that were developed for the guarantee…

  9. INTEREST AND INTELLECTUAL INDICES RELATED TO SUCCESSFUL AND NON-SUCCESSFUL MALE COLLEGE STUDENTS IN TECHNICAL AND ASSOCIATE DEGREE PROGRAMS. FINAL REPORT.

    ERIC Educational Resources Information Center

    HECKER, DONALD L.; TAYLOR, RONALD G.

    THE PURPOSE OF THE PROJECT WAS TO STUDY THE DIFFERENCES AND SIMILARITIES IN INTEREST, ABILITY, AND PREVIOUS ACHIEVEMENT PATTERNS OF 941 MEN STUDENTS WHO ENROLLED IN VARIOUS TECHNICAL AND ASSOCIATE DEGREE 2-YEAR PROGRAMS AND TO DETERMINE WHICH VARIABLES COULD DIFFERENTIATE BETWEEN STUDENTS WHO COMPLETED, CHANGED TO AN ALTERNATE PROGRAM, OR WITHDREW…

  10. Sub-Project 7 of Wisconsin 553, Part F, EPDA--Industry/Exchange Program: Final Report.

    ERIC Educational Resources Information Center

    Wisconsin Univ. - Stout, Menomonie. Center for Vocational, Technical and Adult Education.

    The final report describes a study to develop a statewide teacher/industry exchange program in Wisconsin that would provide vocational-technical instructors with occupational experience opportunities. Three plans for implementing the program were developed: (A) swapping the positions of a business or industrial person with that of a vocational…

  11. 2+2+2 Dissemination Project Final Report.

    ERIC Educational Resources Information Center

    Sloane, Diana; And Others

    An overview is provided in this three-part final report of a project designed to disseminate information to assist California high schools, Regional Occupation Programs, and colleges in developing and strengthening 2+2+2 programs. Part I reviews the following project objectives: (1) hire a project coordinator and technical assistant; (2) develop a…

  12. State Compensatory Education. Final Technical Report 1975-76. Appendixes.

    ERIC Educational Resources Information Center

    Austin Independent School District, TX. Office of Research and Evaluation.

    This material consists of ten appendixes to the Final Report for 1976-77 on the implementation of the Texas state-supported compensatory education program in the Austin Independent School District as evaluated by that district's Office of Research and Evaluation. The instruments used in the evaluation process are described or presented in full,…

  13. Pacific Basin Deaf-Blind Project. State & Multi State Projects for Children with Deaf-Blindness. Final Report, 1992-1995.

    ERIC Educational Resources Information Center

    Kelly, Dotty; Guerrero, Vincent Leon

    This final report describes activities and accomplishments of the Pacific Basin Deaf-Blind Project, a 3-year federally funded project to provide technical assistance to public and private agencies, institutions, and organizations providing early intervention, educational, transitional, vocational, early identification, and related services to…

  14. An Integrated Parent-Teacher-Related Service Team Approach to Communication Intervention. Final Report.

    ERIC Educational Resources Information Center

    Stremel, Kathleen; Wilson, Rebecca

    This final report describes a federally funded 3-year project for integrating related services within educational objectives for children (ages 3-10) with dual vision and hearing impairments. A Training-Utilization model of inservice training and technical assistance was developed, implemented, and evaluated to address the communication needs of…

  15. ADAAG Review Federal Advisory Committee Recommendations for a New ADAAG. Final Report.

    ERIC Educational Resources Information Center

    Architectural and Transportation Barriers Compliance Board, Washington, DC.

    This report presents the final recommendations, in the form of a new set of guidelines, of a federal advisory committee concerning revisions to the Americans with Disabilities Act Accessibility Guidelines (ADAAG). The guidelines provide scoping and technical requirements for the design, construction, and alteration of sites, facilities, buildings,…

  16. 76 FR 78141 - Pilot, Flight Instructor, and Pilot School Certification; Technical Amendment

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-16

    ... command under IFR or in weather conditions less than the minimums prescribed for VFR. Finally, this... pilot in command under IFR or in weather conditions less than the minimums prescribed for VFR. Under... command under IFR or in weather conditions less than the minimums prescribed for VFR. In the 2009 final...

  17. 76 FR 10516 - Transfer and Reorganization of Bank Secrecy Act Regulations-Technical Amendment.

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-25

    ... concerning mutual funds and the other concerning the confidentiality of a report of suspicious activity (SAR... compliance date of the mutual fund rule. Additionally, the Chapter X Final Rule contained an inadvertent..., 2010, FinCEN issued a final rule to include mutual funds within the general definition of ``financial...

  18. Providing Computer-Based Information Services to an Academic Community. Final Technical Report.

    ERIC Educational Resources Information Center

    Bayer, Bernard

    The Mechanized Information Center (MIC) at the Ohio State University conducts retrospective and current awareness searches for faculty, students, and staff using data bases for agriculture, chemistry, education, psychology, and social sciences, as well as a multidisciplinary data base. The final report includes (1) a description of the background…

  19. Project CREATE Final Report. Cooperative Resources To Enhance Access to Technology Education.

    ERIC Educational Resources Information Center

    Hampden County Employment and Training Consortium, Springfield, MA.

    These materials have been developed by Project CREATE (Cooperative Resources to Enhance Access to Jobs through Technical Education), a demonstration program designed to develop a network, specific activities, and resources that would provide education and support services to a wide audience. A 13-page final report describes the hands-on training…

  20. Digital-Computer Processing of Graphical Data. Final Report.

    ERIC Educational Resources Information Center

    Freeman, Herbert

    The final report of a two-year study concerned with the digital-computer processing of graphical data. Five separate investigations carried out under this study are described briefly, and a detailed bibliography, complete with abstracts, is included in which are listed the technical papers and reports published during the period of this program.…

  1. 48 CFR 1852.235-73 - Final Scientific and Technical Reports.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... regarding appropriate electronic formats for final reports is available at http://www.sti.nasa.gov under....nasa.gov under the “Get Help” link. (e) In accordance with paragraph (d) of the Rights in Data—General... contained in NPR 2200.2, Guidelines for Documentation, Approval, and Dissemination of NASA Scientific and...

  2. 48 CFR 1852.235-73 - Final Scientific and Technical Reports.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... regarding appropriate electronic formats for final reports is available at http://www.sti.nasa.gov under....nasa.gov under the “Get Help” link. (e) In accordance with paragraph (d) of the Rights in Data—General... contained in NPR 2200.2, Guidelines for Documentation, Approval, and Dissemination of NASA Scientific and...

  3. 48 CFR 1852.235-73 - Final Scientific and Technical Reports.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... regarding appropriate electronic formats for final reports is available at http://www.sti.nasa.gov under....nasa.gov under the “Get Help” link. (e) In accordance with paragraph (d) of the Rights in Data—General... contained in NPR 2200.2, Guidelines for Documentation, Approval, and Dissemination of NASA Scientific and...

  4. 48 CFR 1852.235-73 - Final Scientific and Technical Reports.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... regarding appropriate electronic formats for final reports is available at http://www.sti.nasa.gov under....nasa.gov under the “Get Help” link. (e) In accordance with paragraph (d) of the Rights in Data—General... contained in NPR 2200.2, Guidelines for Documentation, Approval, and Dissemination of NASA Scientific and...

  5. 10 CFR 52.79 - Contents of applications; technical information in final safety analysis report.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... assurance program will be implemented; (26) The applicant's organizational structure, allocations or... presents a safety analysis of the structures, systems, and components of the facility as a whole. The final... contain an analysis and evaluation of the major structures, systems, and components of the facility that...

  6. PFBC HGCU Test Facility. Technical progress report No. 24, Third quarter, CY 1995

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    NONE

    This is the twenty-fourth and final Technical Progress Report submitted to the Department of Energy (DOE) in connection with the cooperative agreement between the DOE and Ohio Power Company for the Tidd PFBC Hot Gas Clean Up Test Facility. This report covers the work completed during the Third Quarter of CY 1995. All activity this quarter was directed toward the completion of the program final report. A draft copy of the final report was forwarded to DOE during this quarter, and DOE submitted their comments on the report to AEPSC. DOE requested that Westinghouse write an appendix to the reportmore » covering the performance of the fail-safe regenerator devices during Tad operation, and Westinghouse subsequently prepared the appendix. Additional DOE comments were incorporated into the report, and it will be issued in camera-ready form by the end of October, 1995, which is the program end date. Appendix 1 presents the results of filter candle posttest examination by Westinghouse performed on selected filter candles following final shutdown of the system.« less

  7. Conceptual framework of public health surveillance and action and its application in health sector reform.

    PubMed

    McNabb, Scott J N; Chungong, Stella; Ryan, Mike; Wuhib, Tadesse; Nsubuga, Peter; Alemu, Wondi; Carande-Kulis, Vilma; Rodier, Guenael

    2002-01-01

    Because both public health surveillance and action are crucial, the authors initiated meetings at regional and national levels to assess and reform surveillance and action systems. These meetings emphasized improved epidemic preparedness, epidemic response, and highlighted standardized assessment and reform. To standardize assessments, the authors designed a conceptual framework for surveillance and action that categorized the framework into eight core and four support activities, measured with indicators. In application, country-level reformers measure both the presence and performance of the six core activities comprising public health surveillance (detection, registration, reporting, confirmation, analyses, and feedback) and acute (epidemic-type) and planned (management-type) responses composing the two core activities of public health action. Four support activities - communications, supervision, training, and resource provision - enable these eight core processes. National, multiple systems can then be concurrently assessed at each level for effectiveness, technical efficiency, and cost. This approach permits a cost analysis, highlights areas amenable to integration, and provides focused intervention. The final public health model becomes a district-focused, action-oriented integration of core and support activities with enhanced effectiveness, technical efficiency, and cost savings. This reform approach leads to sustained capacity development by an empowerment strategy defined as facilitated, process-oriented action steps transforming staff and the system.

  8. Multiplex Preamplification of Serum DNA to Facilitate Reliable Detection of Extremely Rare Cancer Mutations in Circulating DNA by Digital PCR.

    PubMed

    Jackson, Jennifer B; Choi, Daniel S; Luketich, James D; Pennathur, Arjun; Ståhlberg, Anders; Godfrey, Tony E

    2016-03-01

    Tumor-specific mutations can be identified in circulating, cell-free DNA in plasma or serum and may serve as a clinically relevant alternative to biopsy. Detection of tumor-specific mutations in the plasma, however, is technically challenging. First, mutant allele fractions are typically low in a large background of wild-type circulating, cell-free DNA. Second, the amount of circulating, cell-free DNA acquired from plasma is also low. Even when using digital PCR (dPCR), rare mutation detection is challenging because there is not enough circulating, cell-free DNA to run technical replicates and assay or instrument noise does not easily allow for mutation detection <0.1%. This study was undertaken to improve on the robustness of dPCR for mutation detection. A multiplexed, preamplification step using a high-fidelity polymerase before dPCR was developed to increase total DNA and the number of targets and technical replicates that can be assayed from a single sample. We were able to detect multiple cancer-relevant mutations within tumor-derived samples down to 0.01%. Importantly, the signal/noise ratio was improved for all preamplified targets, allowing for easier discrimination of low-abundance mutations against false-positive signal. Furthermore, we used this protocol on clinical samples to detect known, tumor-specific mutations in patient sera. This study provides a protocol for robust, sensitive detection of circulating tumor DNA for future clinical applications. Copyright © 2016 American Society for Investigative Pathology and the Association for Molecular Pathology. Published by Elsevier Inc. All rights reserved.

  9. Seismicity of the North Atlantic as measured by the International Data Centre using waveform cross correlation

    NASA Astrophysics Data System (ADS)

    Given, J. W.; Bobrov, D.; Kitov, I. O.; Spiliopoulos, S.

    2012-12-01

    The Technical Secretariat (TS) of the Comprehensive Nuclear Test-Ban Treaty Organization (CTBTO) will carry out the verification of the CTBT which obligates each State Party not to carry out any nuclear explosions, independently of their size and purpose. The International Data Centre (IDC) receives, collects, processes, analyses, reports on and archives data from the International Monitoring System(IMS). The IDC is responsible for automatic and interactive processing of the IMS data and for standard IDC products. The IDC is also required by the Treaty to progressively enhance its technical capabilities. In this study, we use waveform cross correlation as a technique to improve the detection capability and reliability of the seismic part of the IMS. In order to quantitatively estimate the gain obtained by cross correlation on the current sensitivity of automatic and interactive processing we compared seismic bulletins built for the North Atlantic (NA), which is an isolated region with earthquakes concentrating around the Mid-Atlantic Ridge. This avoids the influence of adjacent seismic regions on the final bulletins: the Reviewed Event Bulletin (REB) issued by the International Data Centre and the cross correlation Standard Event List (XSEL). We have cross correlated waveforms from ~1500 events reported in the REB since 2009. The resulting cross correlation matrix revealed the best candidates for master events. High-quality signals (SNR>5.0) recorded at eighteen array stations from approximately 50 master events evenly distributed over the seismically active zone in the NA were selected as templates. These templates are used for a continuous calculation of cross correlation coefficients since 2011. All detections obtained by cross-correlation are then used to build events according to the current IDC definition, i.e. at least three primary stations with accurate arrival times, azimuth and slowness estimates. The qualified event hypotheses populated the XSEL. In order to confirm the XSEL events not found in the REB, a portion of the newly built events was reviewed interactively by experienced analysts. The influence of all defining parameters (cross correlation coefficient threshold and SNR, F-statistics and fk-analysis, azimuth and slowness estimates, relative magnitude, etc.) on the final XSEL has been studied using the relevant frequency distributions for all detections vs only for those which were associated with the XSEL events. These distributions are also station and master dependent. This allows estimating the thresholds for all defining parameters, which may be adjusted to balance the rate of missed events and false alarms.

  10. 77 FR 49489 - Oil and Natural Gas Sector: New Source Performance Standards and National Emission Standards for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-16

    ...This action finalizes the review of new source performance standards for the listed oil and natural gas source category. In this action the EPA revised the new source performance standards for volatile organic compounds from leaking components at onshore natural gas processing plants and new source performance standards for sulfur dioxide emissions from natural gas processing plants. The EPA also established standards for certain oil and gas operations not covered by the existing standards. In addition to the operations covered by the existing standards, the newly established standards will regulate volatile organic compound emissions from gas wells, centrifugal compressors, reciprocating compressors, pneumatic controllers and storage vessels. This action also finalizes the residual risk and technology review for the Oil and Natural Gas Production source category and the Natural Gas Transmission and Storage source category. This action includes revisions to the existing leak detection and repair requirements. In addition, the EPA has established in this action emission limits reflecting maximum achievable control technology for certain currently uncontrolled emission sources in these source categories. This action also includes modification and addition of testing and monitoring and related notification, recordkeeping and reporting requirements, as well as other minor technical revisions to the national emission standards for hazardous air pollutants. This action finalizes revisions to the regulatory provisions related to emissions during periods of startup, shutdown and malfunction.

  11. Lessons for surgeons in the final moments of Air France Flight 447.

    PubMed

    Bhangu, Aneel; Bhangu, Sonia; Stevenson, James; Bowley, Douglas M

    2013-06-01

    All surgeons make mistakes, and learning from critical incidents may help improve performance. The present study aimed to highlight lessons for surgeons from analysis of the final moments of Air France Flight 447. All of the authors work in teams and situations where safety, technical performance, and non-technical skills are critical. This review was born out of discussions regarding the events of Flight 447; specifically, whether the airline disaster was relevant to their work, and whether they could learn anything from it. The study is based on review of the crash reports of Flight 447, which lost flight speed indication after formation of ice prevented air from entering flight speed indicators during a storm. Following a subsequent stall, the aircraft fell at a rate of >10,000 feet/min until it crashed into the Atlantic Ocean, killing 228 passengers and crew. There were errors in decision making, reasoning, communication, and teamwork. Such non-technical skills failures have been recognized previously and can be addressed by existing non-technical skills training. A reliance on autopilot meant that the pilots were unfamiliar with high-altitude flying when the autopilot is disengaged. They were unprepared for and affected by such a sudden and serious problem; an event called "surprise and startle" by the accident investigation. The absence of the senior pilot (who was on a scheduled break) in the critical final minutes slowed error recognition and recovery. Unintended consequences of modern safety strategies may be under-recognized and can lead to adverse events. Both simulation-based and non-simulation-based training should include "surprise and startle" events beyond the scenarios trainees might expect. Likewise, in the face of increasing reliance on modern technology, surgeons should ensure that they would be able to perform procedures in the absence of such technologies. Specific training may improve surgeons' non-technical skills, and recognition of such skills could also be used to help select future surgeons.

  12. Memory effects in stock price dynamics: evidences of technical trading

    PubMed Central

    Garzarelli, Federico; Cristelli, Matthieu; Pompa, Gabriele; Zaccaria, Andrea; Pietronero, Luciano

    2014-01-01

    Technical trading represents a class of investment strategies for Financial Markets based on the analysis of trends and recurrent patterns in price time series. According standard economical theories these strategies should not be used because they cannot be profitable. On the contrary, it is well-known that technical traders exist and operate on different time scales. In this paper we investigate if technical trading produces detectable signals in price time series and if some kind of memory effects are introduced in the price dynamics. In particular, we focus on a specific figure called supports and resistances. We first develop a criterion to detect the potential values of supports and resistances. Then we show that memory effects in the price dynamics are associated to these selected values. In fact we show that prices more likely re-bounce than cross these values. Such an effect is a quantitative evidence of the so-called self-fulfilling prophecy, that is the self-reinforcement of agents' belief and sentiment about future stock prices' behavior. PMID:24671011

  13. Memory effects in stock price dynamics: evidences of technical trading

    NASA Astrophysics Data System (ADS)

    Garzarelli, Federico; Cristelli, Matthieu; Pompa, Gabriele; Zaccaria, Andrea; Pietronero, Luciano

    2014-03-01

    Technical trading represents a class of investment strategies for Financial Markets based on the analysis of trends and recurrent patterns in price time series. According standard economical theories these strategies should not be used because they cannot be profitable. On the contrary, it is well-known that technical traders exist and operate on different time scales. In this paper we investigate if technical trading produces detectable signals in price time series and if some kind of memory effects are introduced in the price dynamics. In particular, we focus on a specific figure called supports and resistances. We first develop a criterion to detect the potential values of supports and resistances. Then we show that memory effects in the price dynamics are associated to these selected values. In fact we show that prices more likely re-bounce than cross these values. Such an effect is a quantitative evidence of the so-called self-fulfilling prophecy, that is the self-reinforcement of agents' belief and sentiment about future stock prices' behavior.

  14. Apparently low reproducibility of true differential expression discoveries in microarray studies.

    PubMed

    Zhang, Min; Yao, Chen; Guo, Zheng; Zou, Jinfeng; Zhang, Lin; Xiao, Hui; Wang, Dong; Yang, Da; Gong, Xue; Zhu, Jing; Li, Yanhui; Li, Xia

    2008-09-15

    Differentially expressed gene (DEG) lists detected from different microarray studies for a same disease are often highly inconsistent. Even in technical replicate tests using identical samples, DEG detection still shows very low reproducibility. It is often believed that current small microarray studies will largely introduce false discoveries. Based on a statistical model, we show that even in technical replicate tests using identical samples, it is highly likely that the selected DEG lists will be very inconsistent in the presence of small measurement variations. Therefore, the apparently low reproducibility of DEG detection from current technical replicate tests does not indicate low quality of microarray technology. We also demonstrate that heterogeneous biological variations existing in real cancer data will further reduce the overall reproducibility of DEG detection. Nevertheless, in small subsamples from both simulated and real data, the actual false discovery rate (FDR) for each DEG list tends to be low, suggesting that each separately determined list may comprise mostly true DEGs. Rather than simply counting the overlaps of the discovery lists from different studies for a complex disease, novel metrics are needed for evaluating the reproducibility of discoveries characterized with correlated molecular changes. Supplementaty information: Supplementary data are available at Bioinformatics online.

  15. Liver CT image processing: a short introduction of the technical elements.

    PubMed

    Masutani, Y; Uozumi, K; Akahane, Masaaki; Ohtomo, Kuni

    2006-05-01

    In this paper, we describe the technical aspects of image analysis for liver diagnosis and treatment, including the state-of-the-art of liver image analysis and its applications. After discussion on modalities for liver image analysis, various technical elements for liver image analysis such as registration, segmentation, modeling, and computer-assisted detection are covered with examples performed with clinical data sets. Perspective in the imaging technologies is also reviewed and discussed.

  16. Enhancement of the Probabilistic CEramic Matrix Composite ANalyzer (PCEMCAN) Computer Code

    NASA Technical Reports Server (NTRS)

    Shah, Ashwin

    2000-01-01

    This report represents a final technical report for Order No. C-78019-J entitled "Enhancement of the Probabilistic Ceramic Matrix Composite Analyzer (PCEMCAN) Computer Code." The scope of the enhancement relates to including the probabilistic evaluation of the D-Matrix terms in MAT2 and MAT9 material properties card (available in CEMCAN code) for the MSC/NASTRAN. Technical activities performed during the time period of June 1, 1999 through September 3, 1999 have been summarized, and the final version of the enhanced PCEMCAN code and revisions to the User's Manual is delivered along with. Discussions related to the performed activities were made to the NASA Project Manager during the performance period. The enhanced capabilities have been demonstrated using sample problems.

  17. Technological Innovations in Magnetic Resonance for Early Detection of Cardiovascular Diseases.

    PubMed

    Santarelli, Maria F; Positano, Vincenzo; Martini, Nicola; Valvano, Giuseppe; Landini, Luigi

    2016-01-01

    Most recent technical innovations in cardiovascular MR imaging (CMRI) are presented in this review. They include hardware and software developments, and novelties in parametric mapping. All these recent improvements lead to high spatial and temporal resolution and quantitative information on the heart structure and function. They make it achievable ambitious goals in the field of magnetic resonance, such as the early detection of cardiovascular pathologies. In this review article, we present recent innovations in CMRI, emphasizing the progresses performed and the solutions proposed to some yet opened technical problems.

  18. The anatomy of the gyroscope, part 3

    NASA Astrophysics Data System (ADS)

    Cousins, Frank W.; Hollington, John L.

    1990-03-01

    The gyroscope and its applications are collated with the technical information to be found in the patent literature, augmented by that found in textbooks and technical journels. A detailed consideration is given to early mechanical gyroscopes. Included is a discussion of gyroscopic gears, vibratory gyroscopes, interferometric gyroscopes, and the use of the gyroscope in optical and related devices and deals finally with the difficult problem of gyroscopic inertial drives.

  19. Query Storage and Relay in Research Root (LACREND RR)

    DTIC Science & Technology

    2017-05-30

    QUERY STORAGE AND RELAY IN RESEARCH ROOT (LACREND-RR) UNIVERSITY OF SOUTHERN CALIFORNIA MAY 2017 FINAL TECHNICAL REPORT APPROVED FOR PUBLIC ...exempt from public affairs security and policy review in accordance with SAF/AQR memorandum dated 10 Dec 08 and AFRL/CA policy clarification...memorandum dated 16 Jan 09. This report is available to the general public , including foreign nationals. Copies may be obtained from the Defense Technical

  20. The Chrysler-Weldtech Approach to Retraining Displaced Workers. A Model Project to Develop Specialized Welding Skills Required for Modern Auto Assembly Operations. Final Technical Report.

    ERIC Educational Resources Information Center

    Lyons, Thomas M.; Knight, Glen A.

    A model project was conducted to demonstrate how Chrysler, in partnership with the education community and the government, could provide technical training to enable displaced workers to contribute to the "H-Body" car launch, to improve their job skills, and to enhance their future employability. The training was conducted on a pilot…

  1. Heat pump assisted geothermal heating system for Felix Spa, Romania

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Rosca, Marcel; Maghiar, Teodor

    1996-01-24

    The paper presents a pre-feasibility type study of a proposed heat pump assisted geothermal heating system for an average hotel in Felix Spa, Romania. After a brief presentation of the geothermal reservoir, the paper gives the methodology and the results of the technical and economical calculations. The technical and economical viability of the proposed system is discussed in detail in the final part of the paper.

  2. Heat pump assisted geothermal heating system for Felix Spa, Romania

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Rosca, M.; Maghiar, T.

    1996-12-31

    The paper presents a pre-feasibility type study of a proposed heat pump assisted geothermal heating system for an average hotel in Felix Spa, Romania. After a brief presentation of the geothermal reservoir, the paper gives the methodology and the results of the technical and economical calculations. The technical and economical viability of the proposed system is discussed in detail in the final part of the paper.

  3. The 1990 Johnson Space Center bibliography of scientific and technical papers

    NASA Technical Reports Server (NTRS)

    1991-01-01

    Abstracts are presented of scientific and technical papers written and/or presented by L. B. Johnson Space Center (JSC) authors, including civil servants, contractors, and grantees, during the calendar year of 1990. Citations include conference and symposium presentations, papers published in proceedings or other collective works, seminars, and workshop results, NASA formal report series (including contractually required final reports), and articles published in professional journals.

  4. Solar Heating and Cooling of Buildings: Phase 0. Feasibility and Planning Study. Volume 1: Executive Summary. Document No. 74SD419. Final Report.

    ERIC Educational Resources Information Center

    General Electric Co., Philadelphia, PA. Space Div.

    The purpose of this study was to establish the technical and economic feasibility of using solar energy for the heating and cooling of buildings and to provide baseline information for the widespread application of solar energy. The initial step in this program was a study of the technical, economic, societal, legal, and environmental factors…

  5. Prototype development and demonstration for response, emergency staging, communications, uniform management, and evacuation (R.E.S.C.U.M.E.) : technical report on prototype development and field testing of R.E.S.C.U.M.E. applications.

    DOT National Transportation Integrated Search

    2015-04-01

    This document is the final project technical report for the development and field testing of the Response, Emergency Staging, Communications, Uniform Management, and Evacuation (R.E.S.C.U.M.E.) application bundle, with a focus on the Incident Zone (I...

  6. Review of Military Mountain Medicine Technology and Research Barriers

    DTIC Science & Technology

    2011-09-01

    NORTH ATLANTIC TREATY ORGANISATION RESEARCH AND TECHNOLOGY ORGANISATION AC/323(HFM-146)TP/387 www.rto.nato.int RTO TECHNICAL REPORT TR...montagne et les freins à la recherche) Final Report of Task Group HFM-146. Published September 2011 Distribution and Availability...323(HFM-146)TP/387 www.rto.nato.int RTO TECHNICAL REPORT TR-HFM-146 Review of Military Mountain Medicine Technology and Research Barriers (Point

  7. SELECTIVE DISSEMINATION OF INFORMATION--REVIEW OF SELECTED SYSTEMS AND A DESIGN FOR ARMY TECHNICAL LIBRARIES. FINAL REPORT. ARMY TECHNICAL LIBRARY IMPROVEMENT STUDIES (ATLIS), REPORT NO. 8.

    ERIC Educational Resources Information Center

    BIVONA, WILLIAM A.

    THIS REPORT PRESENTS AN ANALYSIS OF OVER EIGHTEEN SMALL, INTERMEDIATE, AND LARGE SCALE SYSTEMS FOR THE SELECTIVE DISSEMINATION OF INFORMATION (SDI). SYSTEMS ARE COMPARED AND ANALYZED WITH RESPECT TO DESIGN CRITERIA AND THE FOLLOWING NINE SYSTEM PARAMETERS--(1) INFORMATION INPUT, (2) METHODS OF INDEXING AND ABSTRACTING, (3) USER INTEREST PROFILE…

  8. Air Force Research Laboratory Wright Site Guide to Technical Publishing

    DTIC Science & Technology

    2005-04-01

    Scientific and Technical Reports—Elements, Organization, and Design manual (and a version modified for documents generated for AFRL) • Merriam-Webster’s...notice page --SF 298 --original graphics /halftones Indicate the following on the letter of transmittal sheet: --quantity of copies required for...Elements, Organization and Design ? The WRS CDRL for a final report requires that the standard be followed. The only exception is SBIR Phase 1

  9. The Effect of Drycleaning Moisture on Fused Cloth Systems

    DTIC Science & Technology

    1989-03-01

    TECHNICAL REPORT NATICK/TR-89/024 et, THE EFFECT OF DRYCLEANING MOISTURE ON FUSED CLOTH SYSTEMS BY ELIZABETH J. MORELAND International...MOISTUP.E ON FUSED CLOTH SYSTEMS 12. PERSONAL AUTMOR(S) Elizabeth J. MorelanJ 13«. TYPE OF REPORT Final Technical Report 13b. TIME COVERED...This project was initiated to investigate the effect of moisture in drycleaning systems on preselected fused cloth structures. Adverse surface

  10. Annual National Leadership Development Seminar for State Directors of Vocational Education (4th, Las Vegas, Nev., September 14-17, 1971). Comprehensive Personnel Development for Vocational-Technical Education. Final Report.

    ERIC Educational Resources Information Center

    Kazarian, Edward N., Ed.; Ward, Darrell, L., Ed.

    The proceedings of this seminar, attended by state directors and other leaders in vocational and technical education from 41 states, the District of Columbia, Saipan and Puerto Rico, contain presentations by 18 leaders from industry, government, and education. Specific objectives were to: (1) provide a forum for presentations concerning personnel…

  11. Leader Identity, Individual Differences, and Leader Self-Development

    DTIC Science & Technology

    2012-09-01

    and Social Sciences Approved for public release; distribution is unlimited. U.S. Army Research Institute for the Behavioral and Social ... Social Sciences, Attn: DAPC-ARI-MS, 6000 6th Street, Fort Belvoir, VA 22060-5586. FINAL DISPOSITION: Destroy this Technical Report when it is no...longer needed. Do not return it to the U.S. Army Research Institute for the Behavioral and Social Sciences. NOTE: The findings in this Technical

  12. Optimizing Operational Physical Fitness (Optimisation de L’Aptitude Physique Operationnelle)

    DTIC Science & Technology

    2009-01-01

    NORTH ATLANTIC TREATY ORGANISATION RESEARCH AND TECHNOLOGY ORGANISATION AC/323(HFM-080)TP/200 www.rto.nato.int RTO TECHNICAL REPORT TR... RESEARCH AND TECHNOLOGY ORGANISATION AC/323(HFM-080)TP/200 www.rto.nato.int RTO TECHNICAL REPORT TR-HFM-080 Optimizing Operational Physical...Fitness (Optimisation de l’aptitude physique opérationnelle) Final Report of Task Group 019. ii RTO-TR-HFM-080 The Research and

  13. Rating Training Continuum: Development Procedures

    DTIC Science & Technology

    1992-01-01

    During the workshop, the SMEs will need to review technical documents to refresh their memory and resolve any technical issues. It is important that a...endorsement. 7 additional memory space was very useful. The computers with the 80-megabyte hard disk drive were used to collect all final PPPs and TLAs...description, general, and documentation). If you reed to refresh your memory , refer to Figure 3-5 for the definitions associated with the indirectly

  14. Test Plan Development for Plastic Ammunition Containers. Volume 1

    DTIC Science & Technology

    1989-03-15

    1850 Black Canyon Stage¶I Packaging division (SMCAR-AEP) Picatinny Phoenix, Arizona 85027 Arsenal, New Jersey 07806-5000 86. NAME OF FUNDING...packaging containers. The report is presented in two separate volumes. Volume I contains the Final Technical Report and includes the analysis of... Division of the U.S. Army Armament Research, Development and Engineering Center. Mr. Jasper C. Griggs and Mr. D. E. Jones served as technical consultants

  15. Final technical report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Richman, M.

    1996-08-01

    Granular flows of nearly elastic, identical spheres down bumpy inclines are described. A numerical technique is developed to overcome the difficulties associated with the ill-defined `tops` of these flows.

  16. TEAM TRAINING. FINAL TECHNICAL REPORT FEBRUARY 1966-FEBRUARY 1967.

    ERIC Educational Resources Information Center

    BRIGGS, GEORGE E.; JOHNSTON, WILLIAM A.

    THIS IS THE FINAL REPORT ON A FOUR-YEAR PROGRAM OF LABORATORY RESEARCH ON TEAM TRAINING IN A COMBAT INFORMATION CENTER (CIC) CONTEXT. THE RESEARCH LITERATURE ON TEAM TRAINING IS REVIEWED, AND A SET OF CONCLUSIONS IS DRAWN WITH REGARD TO TEAM PERFORMANCE AS A FUNCTION OF TASK, TRAINING, AND COMMUNICATIONS VARIABLES. IN ADDITION, THE IMPLICATIONS…

  17. Development of Advanced Technologies to Reduce Design, Fabrication and Construction Costs for Future Nuclear Power Plants

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    DiNunzio, Camillo A.; Gupta, Abhinav; Golay, Michael

    2002-11-30

    This report presents a summation of the third and final year of a three-year investigation into methods and technologies for substantially reducing the capital costs and total schedule for future nuclear plants. In addition, this is the final technical report for the three-year period of studies.

  18. Validation of Technical Recommendations. Final Report. ISSOE Managing Student Progress.

    ERIC Educational Resources Information Center

    Ridley, Dennis; And Others

    This report is organized to provide a complete, logical presentation of the major steps taken in the third phase of research on dynamics of dissemination of the Instructional Support System for Occupational Education (ISSOE). It reports on the confirmation and validation of the Phase II Final Report on Dissemination Issues and the Phase III…

  19. Georgia Deaf-Blind Project. Final Report, 1992-1995. State and Multi-State Projects for Children with Deaf-Blindness.

    ERIC Educational Resources Information Center

    Georgia State Dept. of Education, Atlanta.

    This final report describes activities and accomplishments of the Georgia Deaf-Blind Project, a 3-year federally supported project encompassing 159 counties and providing technical assistance to 237 infants, children, and youth with deaf-blindness along with their families and their service providers. Project accomplishments included: (1) more…

  20. 78 FR 72641 - Request for Public Comments on Draft Final Report on the Technical Investigation of the May 22...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-03

    ..., 2011 Tornado in Joplin, Missouri AGENCY: National Institute of Standards and Technology, United States... for public comment of the draft final report of the investigation conducted by NIST into the tornado... found on the Joplin Investigation Web page http://www.nist.gov/el/disasterstudies/weather/joplin_tornado...

  1. The Indiana Deafblind Services Project: Services for Children with Deafblindness Program. Final Performance Report.

    ERIC Educational Resources Information Center

    Indiana State Univ., Terre Haute. Blumberg Center for Interdisciplinary Studies in Special Education.

    This final report describes activities and accomplishments of the Indiana Deaf-Blind Services Project, a 4-year federally funded project to enhance and further develop coordinated direct services to children and youth, birth through 2 and ages 18 through 21. The project also was designed to provide technical assistance to public and private…

  2. Two Different Approaches to Teaching Final-Year Projects for Mechanical Engineers and Biotechnologists at Ngee Ann Polytechnic--Case Studies Approach.

    ERIC Educational Resources Information Center

    Walsh, Kath; Rebaczonok-Padulo, Michael

    1993-01-01

    Ngee Ann Polytechnic, a leading postsecondary technical institution in Singapore, offers English for academic and occupational purposes to prepare students for writing their final year projects. This article discusses the approaches used in Mechanical Engineering and Biotechnology projects. A sample exercise is appended. (Contains two references.)…

  3. Computation in the Wild: Moving Beyond the Metaphor

    DTIC Science & Technology

    2006-03-01

    AFRL-IF-RS-TR-2006-105 Final Technical Report March 2006 COMPUTATION IN THE WILD: MOVING BEYOND THE METAPHOR University...Government. AIR FORCE RESEARCH LABORATORY INFORMATION DIRECTORATE ROME RESEARCH SITE ROME, NEW YORK STINFO FINAL REPORT This... report has been reviewed by the Air Force Research Laboratory, Information Directorate, Public Affairs Office (IFOIPA) and is releasable to the National

  4. Illinois State Project: Services for Children with Deaf-Blindness Program. Final Performance Report.

    ERIC Educational Resources Information Center

    Dorsey, Christine

    This final report describes activities and accomplishments of the Illinois state project on services for children with deaf-blindness, a 3-year federally supported project to address the needs of children (ages birth to 21) who are deaf-blind. Project activities included inservice training and technical assistance, development of a comprehensive…

  5. PROJECT PATS: "Potentially Academically Talented Students." Final Technical Report, 10/1/80-6/30/82.

    ERIC Educational Resources Information Center

    Pfeffer, J. S.; And Others

    The final report describes a 2-year pilot project to identify and program for disadvantaged potentially gifted students in grades 5-8. Two goals of the program are stated: (1) to establish a working partnership among public and nonpublic schools and higher education; and (2) to integrate disadvantaged potentially gifted with nondisadvantaged…

  6. Exploration studies technical report, FY1988 status. Volume 1: Technical summary

    NASA Technical Reports Server (NTRS)

    1988-01-01

    The Office of Exploration (OEXP) at NASA Headquarters has been tasked with defining and recommending alternatives for an early 1990's nationaL decision on a focused program of human exploration of the solar system. The Mission Analysis and System Engineering (MASE) group, which is managed by the Exploration Studies Office at the Lyndon B. Johnson Space Center, is responsible for coordinating the technical studies necessary for accomplishing such a task. This technical report, produced by the MASE, describes the process that has been developed in a case study approach. The four case studies developed in FY88 include: (1) Human Expedition to Phobos; (2) Human Expedition to Mars; (3) Lunar Observatory; and (4) Lunar Outpost to Early Mars Evolution. The final outcome of this effort is a set of programmatic and technical conclusions and recommendations for the following year's work.

  7. NASA/DOD Aerospace Knowledge Diffusion Research Project. Paper 37: The impact of political control on technical communications: A comparative study of Russian and US aerospace engineers and scientists

    NASA Technical Reports Server (NTRS)

    Barclay, Rebecca O.; Pinelli, Thomas E.; Flammia, Madelyn; Kennedy, John M.

    1994-01-01

    Until the recent dissolution of the Soviet Union, the Communist Party exerted a strict control of access to and dissemination of scientific and technical information (STI). This article presents models of the Soviet-style information society and the Western-style information society and discusses the effects of centralized governmental control of information on Russian technical communication practices. The effects of political control on technical communication are then used to interpret the results of a survey of Russian and U.S. aerospace engineers and scientists concerning the time devoted to technical communication, their collaborative writing practices and their attitudes toward collaboration, the kinds of technical documents they produce and use, and their use of computer technology, and their use of and the importance to them of libraries and technical information centers. The data are discussed in terms of tentative conclusions drawn from the literature. Finally, we conclude with four questions concerning government policy, collaboration, and the flow of STI between Russian and U.S. aerospace engineers and scientists.

  8. Perfluoro(Methylcyclohexane) Tracer Tagging Test and Demonstration

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sigman, M.E.

    On February 14 and 15, 2000, a demonstration of current perfluorocarbon tagging technology and the future potential of these methods was held at Oak Ridge National Laboratory (ORNL). The demonstration consisted of a brief technical discussion followed by a laboratory demonstration. The laboratory demonstrations included the detection of letters, parcels, briefcases and lockers containing perfluorocarbon-tagged papers. Discrimination between tagged and non-tagged items and between three perfluorocarbon tags was demonstrated along with the detection of perfluorocarbon in a background of non-fluorinated volatile organic solvent. All demonstrations involved real-time detection using a direct sampling ion trap mass spectrometer. The technical results obtainedmore » at ORNL during and in preparation for the demonstration are presented in Appendix 1 to assist Tracer Detection Technology Corp. in further evaluating their position on development and marketing of perfluorocarbon tracer technology.« less

  9. Application of infrared uncooled cameras in surveillance systems

    NASA Astrophysics Data System (ADS)

    Dulski, R.; Bareła, J.; Trzaskawka, P.; PiÄ tkowski, T.

    2013-10-01

    The recent necessity to protect military bases, convoys and patrols gave serious impact to the development of multisensor security systems for perimeter protection. One of the most important devices used in such systems are IR cameras. The paper discusses technical possibilities and limitations to use uncooled IR camera in a multi-sensor surveillance system for perimeter protection. Effective ranges of detection depend on the class of the sensor used and the observed scene itself. Application of IR camera increases the probability of intruder detection regardless of the time of day or weather conditions. It also simultaneously decreased the false alarm rate produced by the surveillance system. The role of IR cameras in the system was discussed as well as technical possibilities to detect human being. Comparison of commercially available IR cameras, capable to achieve desired ranges was done. The required spatial resolution for detection, recognition and identification was calculated. The simulation of detection ranges was done using a new model for predicting target acquisition performance which uses the Targeting Task Performance (TTP) metric. Like its predecessor, the Johnson criteria, the new model bounds the range performance with image quality. The scope of presented analysis is limited to the estimation of detection, recognition and identification ranges for typical thermal cameras with uncooled microbolometer focal plane arrays. This type of cameras is most widely used in security systems because of competitive price to performance ratio. Detection, recognition and identification range calculations were made, and the appropriate results for the devices with selected technical specifications were compared and discussed.

  10. Passive Detection of Misbehaving Name Servers

    DTIC Science & Technology

    2013-10-01

    Passive Detection of Misbehaving Name Servers Leigh B. Metcalf Jonathan M. Spring October 2013 TECHNICAL REPORT CMU/SEI-2013-TR-010 ESC-TR...Detection of Misbehaving Name Servers 5. FUNDING NUMBERS FA8721-05-C-0003 6. AUTHOR(S) Leigh B. Metcalf and Jonathan M. Spring 7. PERFORMING

  11. Towards a just, courageous, and honest resolution of the futility debate.

    PubMed

    Tong, R

    1995-04-01

    This essay discusses the history of the "futility debate" and the motives that sometimes prompt health care professionals, health care providers, patients, and surrogates to take different sides in it. Changes in the health care system, financial responsibility shifts, technical medical advances, and medical care rationing are analyzed as contributors to the futility debate. So too are variations in the definition of futility examined as part of the current controversy. The respective attitudes of professionals, providers, patients, and surrogates in accepting the goals, capabilities, and limits of medicine are also explored. In particular, the lack of honest communication between health care professionals/health care providers on the one hand and patients/surrogates on the other is acknowledged as a major roadblock in the building of care-focused futility policies. Finally, various initial attempts of hospitals to create futility guidelines are evaluated in order to detect problem areas and to suggest lines of improvement.

  12. Massively parallel digital transcriptional profiling of single cells

    PubMed Central

    Zheng, Grace X. Y.; Terry, Jessica M.; Belgrader, Phillip; Ryvkin, Paul; Bent, Zachary W.; Wilson, Ryan; Ziraldo, Solongo B.; Wheeler, Tobias D.; McDermott, Geoff P.; Zhu, Junjie; Gregory, Mark T.; Shuga, Joe; Montesclaros, Luz; Underwood, Jason G.; Masquelier, Donald A.; Nishimura, Stefanie Y.; Schnall-Levin, Michael; Wyatt, Paul W.; Hindson, Christopher M.; Bharadwaj, Rajiv; Wong, Alexander; Ness, Kevin D.; Beppu, Lan W.; Deeg, H. Joachim; McFarland, Christopher; Loeb, Keith R.; Valente, William J.; Ericson, Nolan G.; Stevens, Emily A.; Radich, Jerald P.; Mikkelsen, Tarjei S.; Hindson, Benjamin J.; Bielas, Jason H.

    2017-01-01

    Characterizing the transcriptome of individual cells is fundamental to understanding complex biological systems. We describe a droplet-based system that enables 3′ mRNA counting of tens of thousands of single cells per sample. Cell encapsulation, of up to 8 samples at a time, takes place in ∼6 min, with ∼50% cell capture efficiency. To demonstrate the system's technical performance, we collected transcriptome data from ∼250k single cells across 29 samples. We validated the sensitivity of the system and its ability to detect rare populations using cell lines and synthetic RNAs. We profiled 68k peripheral blood mononuclear cells to demonstrate the system's ability to characterize large immune populations. Finally, we used sequence variation in the transcriptome data to determine host and donor chimerism at single-cell resolution from bone marrow mononuclear cells isolated from transplant patients. PMID:28091601

  13. Large-scale purification of 90Sr from nuclear waste materials for production of 90Y, a therapeutic medical radioisotope.

    PubMed

    Wester, Dennis W; Steele, Richard T; Rinehart, Donald E; DesChane, Jaquetta R; Carson, Katharine J; Rapko, Brian M; Tenforde, Thomas S

    2003-07-01

    A major limitation on the supply of the short-lived medical isotope 90Y (t1/2 = 64 h) is the available quantity of highly purified 90Sr generator material. A radiochemical production campaign was therefore undertaken to purify 1,500 Ci of 90Sr that had been isolated from fission waste materials. A series of alkaline precipitation steps removed all detectable traces of 137Cs, alpha emitters, and uranium and transuranic elements. Technical obstacles such as the buildup of gas pressure generated upon mixing large quantities of acid with solid 90Sr carbonate were overcome through safety features incorporated into the custom-built equipment used for 90Sr purification. Methods are described for analyzing the chemical and radiochemical purity of the final product and for accurately determining by gravimetry the quantities of 90Sr immobilized on stainless steel filters for future use.

  14. Admiralty Inlet Pilot Tidal Project Final Technical Report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Collar, Craig

    This document represents the final report for the Admiralty Inlet Pilot Tidal Project, located in Puget Sound, Washington, United States. The Project purpose was to license, permit, and install a grid-connected deep-water tidal turbine array (two turbines) to be used as a platform to gather operational and environmental data on tidal energy generation. The data could then be used to better inform the viability of commercial tidal energy generation from technical, economic, social, and environmental standpoints. This data would serve as a critical step towards the responsible advancement of commercial scale tidal energy in the United States and around themore » world. In late 2014, Project activities were discontinued due to escalating costs, and the DOE award was terminated in early 2015. Permitting, licensing, and engineering design activities were completed under this award. Final design, deployment, operation, and monitoring were not completed. This report discusses the results and accomplishments achieved under the subject award.« less

  15. Dispersive detection of radio-frequency-dressed states

    NASA Astrophysics Data System (ADS)

    Jammi, Sindhu; Pyragius, Tadas; Bason, Mark G.; Florez, Hans Marin; Fernholz, Thomas

    2018-04-01

    We introduce a method to dispersively detect alkali-metal atoms in radio-frequency-dressed states. In particular, we use dressed detection to measure populations and population differences of atoms prepared in their clock states. Linear birefringence of the atomic medium enables atom number detection via polarization homodyning, a form of common path interferometry. In order to achieve low technical noise levels, we perform optical sideband detection after adiabatic transformation of bare states into dressed states. The balanced homodyne signal then oscillates independently of field fluctuations at twice the dressing frequency, thus allowing for robust, phase-locked detection that circumvents low-frequency noise. Using probe pulses of two optical frequencies, we can detect both clock states simultaneously and obtain population difference as well as the total atom number. The scheme also allows for difference measurements by direct subtraction of the homodyne signals at the balanced detector, which should technically enable quantum noise limited measurements with prospects for the preparation of spin squeezed states. The method extends to other Zeeman sublevels and can be employed in a range of atomic clock schemes, atom interferometers, and other experiments using dressed atoms.

  16. Detection of Rare Drug Resistance Mutations by Digital PCR in a Human Influenza A Virus Model System and Clinical Samples

    PubMed Central

    Bushell, Claire A.; Grant, Paul R.; Cowen, Simon; Gutierrez-Aguirre, Ion; O'Sullivan, Denise M.; Žel, Jana; Milavec, Mojca; Foy, Carole A.; Nastouli, Eleni; Garson, Jeremy A.; Huggett, Jim F.

    2015-01-01

    Digital PCR (dPCR) is being increasingly used for the quantification of sequence variations, including single nucleotide polymorphisms (SNPs), due to its high accuracy and precision in comparison with techniques such as quantitative PCR (qPCR) and melt curve analysis. To develop and evaluate dPCR for SNP detection using DNA, RNA, and clinical samples, an influenza virus model of resistance to oseltamivir (Tamiflu) was used. First, this study was able to recognize and reduce off-target amplification in dPCR quantification, thereby enabling technical sensitivities down to 0.1% SNP abundance at a range of template concentrations, a 50-fold improvement on the qPCR assay used routinely in the clinic. Second, a method was developed for determining the false-positive rate (background) signal. Finally, comparison of dPCR with qPCR results on clinical samples demonstrated the potential impact dPCR could have on clinical research and patient management by earlier (trace) detection of rare drug-resistant sequence variants. Ultimately this could reduce the quantity of ineffective drugs taken and facilitate early switching to alternative medication when available. In the short term such methods could advance our understanding of microbial dynamics and therapeutic responses in a range of infectious diseases such as HIV, viral hepatitis, and tuberculosis. Furthermore, the findings presented here are directly relevant to other diagnostic areas, such as the detection of rare SNPs in malignancy, monitoring of graft rejection, and fetal screening. PMID:26659206

  17. Detection of Rare Drug Resistance Mutations by Digital PCR in a Human Influenza A Virus Model System and Clinical Samples.

    PubMed

    Whale, Alexandra S; Bushell, Claire A; Grant, Paul R; Cowen, Simon; Gutierrez-Aguirre, Ion; O'Sullivan, Denise M; Žel, Jana; Milavec, Mojca; Foy, Carole A; Nastouli, Eleni; Garson, Jeremy A; Huggett, Jim F

    2016-02-01

    Digital PCR (dPCR) is being increasingly used for the quantification of sequence variations, including single nucleotide polymorphisms (SNPs), due to its high accuracy and precision in comparison with techniques such as quantitative PCR (qPCR) and melt curve analysis. To develop and evaluate dPCR for SNP detection using DNA, RNA, and clinical samples, an influenza virus model of resistance to oseltamivir (Tamiflu) was used. First, this study was able to recognize and reduce off-target amplification in dPCR quantification, thereby enabling technical sensitivities down to 0.1% SNP abundance at a range of template concentrations, a 50-fold improvement on the qPCR assay used routinely in the clinic. Second, a method was developed for determining the false-positive rate (background) signal. Finally, comparison of dPCR with qPCR results on clinical samples demonstrated the potential impact dPCR could have on clinical research and patient management by earlier (trace) detection of rare drug-resistant sequence variants. Ultimately this could reduce the quantity of ineffective drugs taken and facilitate early switching to alternative medication when available. In the short term such methods could advance our understanding of microbial dynamics and therapeutic responses in a range of infectious diseases such as HIV, viral hepatitis, and tuberculosis. Furthermore, the findings presented here are directly relevant to other diagnostic areas, such as the detection of rare SNPs in malignancy, monitoring of graft rejection, and fetal screening. Copyright © 2016 Whale et al.

  18. Cost comparison of axillary sentinel lymph node detection and axillary lymphadenectomy in early breast cancer. A national study based on a prospective multi-institutional series of 985 patients ‘on behalf of the Group of Surgeons from the French Unicancer Federation’

    PubMed Central

    Classe, J. M.; Baffert, S.; Sigal-Zafrani, B.; Fall, M.; Rousseau, C.; Alran, S.; Rouanet, P.; Belichard, C.; Mignotte, H.; Ferron, G.; Marchal, F.; Giard, S.; Tunon de Lara, C.; Le Bouedec, G.; Cuisenier, J.; Werner, R.; Raoust, I.; Rodier, J.-F.; Laki, F.; Colombo, P.-E.; Lasry, S.; Faure, C.; Charitansky, H.; Olivier, J.-B.; Chauvet, M.-P.; Bussières, E.; Gimbergues, P.; Flipo, B.; Houvenaeghel, G.; Dravet, F.; Livartowski, A.

    2012-01-01

    Background: Our objective was to assess the global cost of the sentinel lymph node detection [axillary sentinel lymph node detection (ASLND)] compared with standard axillary lymphadenectomy [axillary lymph node dissection (ALND)] for early breast cancer patients. Patients and methods: We conducted a prospective, multi-institutional, observational, cost comparative analysis. Cost calculations were realized with the micro-costing method from the diagnosis until 1 month after the last surgery. Results: Eight hundred and thirty nine patients were included in the ASLND group and 146 in the ALND group. The cost generated for a patient with an ASLND, with one preoperative scintigraphy, a combined method for sentinel node detection, an intraoperative pathological analysis without lymphadenectomy, was lower than the cost generated for a patient with lymphadenectomy [€2947 (σ = 580) versus €3331 (σ = 902); P = 0.0001]. Conclusion: ASLND, involving expensive techniques, was finally less expensive than ALND. The length of hospital stay was the cost driver of these procedures. The current observational study points the heterogeneous practices for this validated and largely diffused technique. Several technical choices have an impact on the cost of ASLND, as intraoperative analysis allowing to reduce rehospitalization rate for secondary lymphadenectomy or preoperative scintigraphy, suggesting possible savings on hospital resources. PMID:21896543

  19. Final Technical Report for Years 1-4 of the Early Career Research Project "Viscosity and equation of state of hot and dense QCD matter" - ARRA portion

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Molnar, Denes

    2014-04-14

    The Section below summarizes research activities and achievements during the first four years of the PI’s Early Career Research Project (ECRP). Two main areas have been advanced: i) radiative 3 ↔ 2 radiative transport, via development of a new computer code MPC/Grid that solves the Boltzmann transport equation in full 6+1D (3X+3V+time) on both single-CPU and parallel computers; ii) development of a self-consistent framework to convert viscous fluids to particles, and application of this framework to relativistic heavy-ion collisions, in particular, determination of the shear viscosity. Year 5 of the ECRP is under a separate award number, and therefore itmore » has its own report document ’Final Technical Report for Year 5 of the Early Career Research Project “Viscosity and equation of state of hot and dense QCDmatter”’ (award DE-SC0008028). The PI’s group was also part of the DOE JET Topical Collaboration, a multi-institution project that overlapped in time significantly with the ECRP. Purdue achievements as part of the JET Topical Collaboration are in a separate report “Final Technical Report summarizing Purdue research activities as part of the DOE JET Topical Collaboration” (award DE-SC0004077).« less

  20. Internal dosimetry technical basis manual

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    1990-12-20

    The internal dosimetry program at the Savannah River Site (SRS) consists of radiation protection programs and activities used to detect and evaluate intakes of radioactive material by radiation workers. Examples of such programs are: air monitoring; surface contamination monitoring; personal contamination surveys; radiobioassay; and dose assessment. The objectives of the internal dosimetry program are to demonstrate that the workplace is under control and that workers are not being exposed to radioactive material, and to detect and assess inadvertent intakes in the workplace. The Savannah River Site Internal Dosimetry Technical Basis Manual (TBM) is intended to provide a technical and philosophicalmore » discussion of the radiobioassay and dose assessment aspects of the internal dosimetry program. Detailed information on air, surface, and personal contamination surveillance programs is not given in this manual except for how these programs interface with routine and special bioassay programs.« less

  1. SSME propellant path leak detection real-time

    NASA Technical Reports Server (NTRS)

    Crawford, R. A.; Smith, L. M.

    1994-01-01

    Included are four documents that outline the technical aspects of the research performed on NASA Grant NAG8-140: 'A System for Sequential Step Detection with Application to Video Image Processing'; 'Leak Detection from the SSME Using Sequential Image Processing'; 'Digital Image Processor Specifications for Real-Time SSME Leak Detection'; and 'A Color Change Detection System for Video Signals with Applications to Spectral Analysis of Rocket Engine Plumes'.

  2. Navajo Electrification Demonstraiton Project

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Larry Ahasteen, Project Manager

    2006-07-17

    This is a final technical report required by DOE for the Navajo Electrification Demonstration Program, This report covers the electric line extension project for Navajo families that currently without electric power.

  3. Cattail-to-alcohol project. Final technical report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    None

    1982-01-01

    Harvesting, grinding, and fermentation of cattails and/or their rhizomes are described. The use of antibiotics to prevent massive contamination of microorganisms and cessation of fermentation is discussed.

  4. National Training Center (NTC) Analysis

    DTIC Science & Technology

    1981-05-29

    CONTRACT FOR S100K NTC CONCEPT STUDY PRESENTATION TO DARPA/TRADOC SIOOK ADD- ON FOR FURTHER NTC CONCEPT DEVELOPMENT SAI CONCEPT FOR 1-ALPHA...Technical Report 29 May 1981 I I I This document is submitted in fulfillment of contract No. DAAK 40-78-C-0198. It is the final report on Phase 1...many technical reports have been published previously. This report draws on these earlier reports and presents a comprehensive summary and overview

  5. A Review and Evaluation of the Langley Research Center's Scientific and Technical Information Program. Results of Phase I--Knowledge and Attitudes Survey, LaRC Research Personnel. Final Report.

    ERIC Educational Resources Information Center

    Pinelli, Thomas E.; And Others

    As Phase I of a comprehensive evaluation of the NASA-affiliated Langley Research Center's (LaRC) scientific and technical information (STI) program, an internal survey was conducted to obtain feedback from LaRC scientists and engineers concerning the effectiveness of the STI program. The first stage of the survey, which involved interviews with 64…

  6. A Review and Evaluation of the Langley Research Center's Scientific and Technical Information Program. Results of Phase IV--Knowledge and Attitudes Survey, Academic and Industrial Personnel. Final Report.

    ERIC Educational Resources Information Center

    Pinelli, Thomas E.; And Others

    As Phase IV of a comprehensive evaluation of the NASA-affiliated Langley Research Center's (LaRC) scientific and technical information (STI) program, a study was conducted to assess the usage, importance, and perceived quality of Langley-generated STI among academic and industrial research personnel, and to determine ways in which that information…

  7. Microelectronics Status Analysis and Secondary Part Procureability Assessment of the THAAD Weapon System

    DTIC Science & Technology

    1999-10-01

    Technical Report 5-20448 & 5- 20449 Contract No. DAAH01-98-D-R001 Delivery Order No. 34 Microelectronics Status Analysis and Secondary Part...Procureability Assessment of the THAAD Weapon System. (5-20448 & 5- 20449 ) Final Technical Report for Period 21 January 1999 through 30 September 1999...Huntsville Huntsville, AL 35899 5. FUNDING NUMBERS 8. PERFORMING ORGANIZATION REPORT NUMBER 5-20448 & 5- 20449 9. SPONSORING/MONITORING AGENCY

  8. Final Technical Report: "Achieving Regional Energy Efficiency Potential in the Southeast”

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mahoney, Mandy

    The overall objective of this award was to facilitate sharing of DOE resources and best practices as well as provide technical assistance to key stakeholders to support greater compliance with energy efficiency standards and increased energy savings. The outcomes of this award include greater awareness among key stakeholders on energy efficiency topics, increased deployment and utilization of DOE resources, and effective policies and programs to support energy efficiency in the Southeast.

  9. Triple Helix

    DTIC Science & Technology

    2008-08-01

    and sponsoring FIRST teams at the Junior FIRST Lego League (JFLL) and the FIRST Lego League (FLL) levels in elementary and middle school . As such, the...a Final Technical Report for Year I Grant W911NF-07-1-0663 with the Newport News Public School District for the Menchville High School Robotics Team...August 2008 TRIPL HELIX 0 Menchville High School Newport News, VA 20080829081 w DEFENSE TECHNICAL INFORMATION CENTER bfro do.A icfr tkw, Def&*ue, Cow

  10. Review of Interventions for Reducing Enlisted Attrition in the U.S. Military: An Update

    DTIC Science & Technology

    2009-06-01

    by ARI. Please address correspondence concerning distribution of reports to: U.S. Research Institute for the Behavioral and Social Sciences, Attn...DAPE-ARI-ZXM, 2511 Jefferson Davis Highway, Arlington, Virginia 22202-3926 FINAL DISPOSITION: This Technical Report may be destroyed when it...this Technical Report are not to be construed as an official Department of the Army position, unless so designated by other authorized documents. i

  11. Navy Technical Information Presentation System (NTIPS) Test and Implementation Strategy

    DTIC Science & Technology

    1981-12-01

    IC AROEROCK I NAOI S ~ i P RF R M N C AVI AT OIO N A N DDEPARTMENT STIPRUCTRMNES COMPUATIONAN DEPARTMENT -MATHEMATICS AND 17 LOGISTICS DEPARTMENT leI...and Subtitle) S . TYPE OF REPORT & PERIOD COVERED NAVY TECHNICAL INFORMATION PRESENTATION Final SYSTEM (NTIPS) TEST AND IMPLEMENTATION 6. PERFORMING...CLASSIFICATION OP THIS PAGE (1nor. Data Enteed) ock 20 continued) system operation, training, maintenance, and logistics support. This system was

  12. Equipment Loan Inventory

    DTIC Science & Technology

    1993-03-01

    1993 A Final Technical Report B 0 RF A Approved for public release; distribution is unlimited. T 0 R 93-12309;.801 01 7 lllli/liillU!ll11!tl AIR FORCE... publication is for illustration purposes and does not constitute endorsement or recommendaticn for usc by th• United States Air Force. The Office of... Public Affairs has reviewed this report, and it is releasable to the National Technical Information Service, where it will be available to the general

  13. From embodied mind to embodied robotics: humanities and system theoretical aspects.

    PubMed

    Mainzer, Klaus

    2009-01-01

    After an introduction (1) the article analyzes the evolution of the embodied mind (2), the innovation of embodied robotics (3), and finally discusses conclusions of embodied robotics for human responsibility (4). Considering the evolution of the embodied mind (2), we start with an introduction of complex systems and nonlinear dynamics (2.1), apply this approach to neural self-organization (2.2), distinguish degrees of complexity of the brain (2.3), explain the emergence of cognitive states by complex systems dynamics (2.4), and discuss criteria for modeling the brain as complex nonlinear system (2.5). The innovation of embodied robotics (3) is a challenge of future technology. We start with the distinction of symbolic and embodied AI (3.1) and explain embodied robots as dynamical systems (3.2). Self-organization needs self-control of technical systems (3.3). Cellular neural networks (CNN) are an example of self-organizing technical systems offering new avenues for neurobionics (3.4). In general, technical neural networks support different kinds of learning robots (3.5). Finally, embodied robotics aim at the development of cognitive and conscious robots (3.6).

  14. Advanced transportation system studies technical area 2(TA-2): Heavy lift launch vehicle development. volume 1; Executive summary

    NASA Technical Reports Server (NTRS)

    McCurry, J.

    1995-01-01

    The purpose of the TA-2 contract was to provide advanced launch vehicle concept definition and analysis to assist NASA in the identification of future launch vehicle requirements. Contracted analysis activities included vehicle sizing and performance analysis, subsystem concept definition, propulsion subsystem definition (foreign and domestic), ground operations and facilities analysis, and life cycle cost estimation. This document is part of the final report for the TA-2 contract. The final report consists of three volumes: Volume 1 is the Executive Summary, Volume 2 is Technical Results, and Volume 3 is Program Cost Estimates. The document-at-hand, Volume 1, provides a summary description of the technical activities that were performed over the entire contract duration, covering three distinct launch vehicle definition activities: heavy-lift (300,000 pounds injected mass to low Earth orbit) launch vehicles for the First Lunar Outpost (FLO), medium-lift (50,000-80,000 pounds injected mass to low Earth orbit) launch vehicles, and single-stage-to-orbit (SSTO) launch vehicles (25,000 pounds injected mass to a Space Station orbit).

  15. Identification of technical item flaws leads to improvement of the quality of single best Multiple Choice Questions.

    PubMed

    Fayyaz Khan, Humaira; Farooq Danish, Khalid; Saeed Awan, Azra; Anwar, Masood

    2013-05-01

    The purpose of the study was to identify technical item flaws in the multiple choice questions submitted for the final exams for the years 2009, 2010 and 2011. This descriptive analytical study was carried out in Islamic International Medical College (IIMC). The Data was collected from the MCQ's submitted by the faculty for the final exams for the year 2009, 2010 and 2011. The data was compiled and evaluated by a three member assessment committee. The data was analyzed for frequency and percentages the categorical data was analyzed by chi-square test. Overall percentage of flawed item was 67% for the year 2009 of which 21% were for testwiseness and 40% were for irrelevant difficulty. In year 2010 the total item flaws were 36% and 11% testwiseness and 22% were for irrelevant difficulty. The year 2011 data showed decreased overall flaws of 21%. The flaws of testwisness were 7%, irrelevant difficulty were 11%. Technical item flaws are frequently encountered during MCQ construction, and the identification of flaws leads to improved quality of the single best MCQ's.

  16. Advanced High Temperature Polymer Matrix Composites for Gas Turbine Engines Program Expansion

    NASA Technical Reports Server (NTRS)

    Hanley, David; Carella, John

    1999-01-01

    This document, submitted by AlliedSignal Engines (AE), a division of AlliedSignal Aerospace Company, presents the program final report for the Advanced High Temperature Polymer Matrix Composites for Gas Turbine Engines Program Expansion in compliance with data requirements in the statement of work, Contract No. NAS3-97003. This document includes: 1 -Technical Summary: a) Component Design, b) Manufacturing Process Selection, c) Vendor Selection, and d) Testing Validation: 2-Program Conclusion and Perspective. Also, see the Appendix at the back of this report. This report covers the program accomplishments from December 1, 1996, to August 24, 1998. The Advanced High Temperature PMC's for Gas Turbine Engines Program Expansion was a one year long, five task technical effort aimed at designing, fabricating and testing a turbine engine component using NASA's high temperature resin system AMB-21. The fiber material chosen was graphite T650-35, 3K, 8HS with UC-309 sizing. The first four tasks included component design and manufacturing, process selection, vendor selection, component fabrication and validation testing. The final task involved monthly financial and technical reports.

  17. Determination of technical grade isocyanates used in the production of polyurethane plastics.

    PubMed

    Marand, Asa; Dahlin, Jakob; Karlsson, Daniel; Skarping, Gunnar; Dalene, Marianne

    2004-07-01

    A method for determination of technical grade isocyanates used in the production of polyurethane (PUR) is presented. The isocyanates in technical grade products were characterised as di-n-butylamine (DBA) derivatives using LC-MS and LC-chemiluminescent nitrogen detection (CLND) and the total isocyanate content was compared to a titration assay. For collection of isocyanates in air, an impinger-filter sampling technique with DBA as derivatisation reagent was used. Characterised DBA and nonadeuterium labelled DBA derivatives of isocyanates in technical products were used as calibration standards and internal standards, respectively, in the analysis of air samples. Three workplaces were studied where PUR products were produced either by spraying or by moulding. In both technical products and in air samples, a number of monomeric, oligomeric and prepolymeric isocyanates of e.g. methylenebisphenyl diisocyanate (MDI) and hexamethylene diisocyanate (HDI) were characterised. Several of these have not previously been described in workplace atmospheres. In the technical isocyanate products, between 69 and 102% of the NCO content determined by titration was accounted for by LC-CLND. Quantifications of a wide range of isocyanates in air samples were performed with correlation coefficients in the range 0.988-0.999 (n= 8) and the instrumental detection limits were 0.7-25 pg. At the two workplaces where MDI- and HDI isocyanurate-based products were sprayed, the isocyanate composition in the air reflected the composition in the technical product. At the workplace where a MDI-based product was used in a moulding process, only the monomeric isocyanates were found in the air. The advantage of using characterised technical grade isocyanates as analytical standards was clearly demonstrated and the possibility of using index compounds when monitoring isocyanate exposure is discussed.

  18. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Tagestad, Jerry D.; Bolte, John; Guzy, Michael

    During this final year of the Pacific Northwest Regional Collaboratory we focused significantly on continuing the relationship between technical teams and government end-users. The main theme of the year was integration. This took the form of data integration via our web portal and integration of our technologies with the end users. The PNWRC's technical portfolio is based on EOS strategies, and focuses on 'applications of national priority: water management, invasive species, coastal management and ecological forecasting.' The products of our technical approaches have been well received by the community of focused end-users. The objective this year was to broaden thatmore » community and develop external support to continue and operationalize product development.« less

  19. Diverse knowledges and competing interests: an essay on socio-technical problem-solving.

    PubMed

    di Norcia, Vincent

    2002-01-01

    Solving complex socio-technical problems, this paper claims, involves diverse knowledges (cognitive diversity), competing interests (social diversity), and pragmatism. To explain this view, this paper first explores two different cases: Canadian pulp and paper mill pollution and siting nuclear reactors in systematically sensitive areas of California. Solving such socio-technically complex problems involves cognitive diversity as well as social diversity and pragmatism. Cognitive diversity requires one to not only recognize relevant knowledges but also to assess their validity. Finally, it is suggested, integrating the resultant set of diverse relevant and valid knowledges determines the parameters of the solution space for the problem.

  20. Deep neural network-based computer-assisted detection of cerebral aneurysms in MR angiography.

    PubMed

    Nakao, Takahiro; Hanaoka, Shouhei; Nomura, Yukihiro; Sato, Issei; Nemoto, Mitsutaka; Miki, Soichiro; Maeda, Eriko; Yoshikawa, Takeharu; Hayashi, Naoto; Abe, Osamu

    2018-04-01

    The usefulness of computer-assisted detection (CAD) for detecting cerebral aneurysms has been reported; therefore, the improved performance of CAD will help to detect cerebral aneurysms. To develop a CAD system for intracranial aneurysms on unenhanced magnetic resonance angiography (MRA) images based on a deep convolutional neural network (CNN) and a maximum intensity projection (MIP) algorithm, and to demonstrate the usefulness of the system by training and evaluating it using a large dataset. Retrospective study. There were 450 cases with intracranial aneurysms. The diagnoses of brain aneurysms were made on the basis of MRA, which was performed as part of a brain screening program. Noncontrast-enhanced 3D time-of-flight (TOF) MRA on 3T MR scanners. In our CAD, we used a CNN classifier that predicts whether each voxel is inside or outside aneurysms by inputting MIP images generated from a volume of interest (VOI) around the voxel. The CNN was trained in advance using manually inputted labels. We evaluated our method using 450 cases with intracranial aneurysms, 300 of which were used for training, 50 for parameter tuning, and 100 for the final evaluation. Free-response receiver operating characteristic (FROC) analysis. Our CAD system detected 94.2% (98/104) of aneurysms with 2.9 false positives per case (FPs/case). At a sensitivity of 70%, the number of FPs/case was 0.26. We showed that the combination of a CNN and an MIP algorithm is useful for the detection of intracranial aneurysms. 4 Technical Efficacy: Stage 1 J. Magn. Reson. Imaging 2018;47:948-953. © 2017 International Society for Magnetic Resonance in Medicine.

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