The StreamCat Dataset: Accumulated Attributes for NHDPlusV2 Catchments (Version 2.1) for the Conterminous United States: Dam Density and Storage Volume

EPA Pesticide Factsheets

This dataset represents the dam density and storage volumes within individual, local NHDPlusV2 catchments and upstream, contributing watersheds based on National Inventory of Dams (NID) data. Attributes were calculated for every local NHDPlusV2 catchment and accumulated to provide watershed-level metrics.(See Supplementary Info for Glossary of Terms) The NID database contains information about the dam??s location, size, purpose, type, last inspection, regulatory facts, and other technical data. Structures on streams reduce the longitudinal and lateral hydrologic connectivity of the system. For example, impoundments above dams slow stream flow, cause deposition of sediment and reduce peak flows. Dams change both the discharge and sediment supply of streams, causing channel incision and bed coarsening downstream. Downstream areas are often sediment deprived, resulting in degradation, i.e., erosion of the stream bed and stream banks. This database was improved upon by locations verified by work from the USGS National Map (Jeff Simley Group). It was observed that some dams, some of them major and which do exist, were not part of the 2009 NID, but were represented in the USGS National Map dataset, and had been in the 2006 NID. Approximately 1,100 such dams were added, based on the USGS National Map lat/long and the 2006 NID attributes (dam height, storage, etc.) Finally, as clean-up, a) about 600 records with duplicate NIDID were removed, and b) about 300 reco

Polio as a platform: using national immunization days to deliver vitamin A supplements.

PubMed Central

Goodman, T.; Dalmiya, N.; de Benoist, B.; Schultink, W.

2000-01-01

In 1988 the 41st World Health Assembly committed WHO to the goal of global eradication of poliomyelitis by 2000 "in ways which strengthen national immunization programmes and health infrastructure". The successful use of polio National Immunization Days (NIDs) to deliver vitamin A is an example of how polio eradication can serve as a platform to address other problems of child health. Importantly, this integration is helping to achieve the World Summit for Children goal of eliminating vitamin A deficiency by the year 2000. It is estimated that between 140 million and 250 million preschool children are at risk of subclinical vitamin A deficiency. In 1998 more than 60 million children at risk received vitamin A supplements during polio national immunization days (NIDs). While food fortification and dietary approaches are fundamental to combating vitamin A deficiency, the administration of vitamin A supplements during NIDs helps raise awareness, enhance technical capacity, improve assessment and establish a reporting system. Moreover, polio NIDs provide an entry point for the sustainable provision of vitamin A supplements with routine immunization services and demonstrate how immunization campaigns can be used for the delivery of other preventive health services. PMID:10812726

Vitamin A or E and a catechin synergize as vaccine adjuvant to enhance immune responses in mice by induction of early interleukin-15 but not interleukin-1β responses.

PubMed

Patel, Sapna; Akalkotkar, Archana; Bivona, Joseph J; Lee, Ji-Young; Park, Young-Ki; Yu, Mingke; Colpitts, Sara L; Vajdy, Michael

2016-08-01

Vitamins A and E and select flavonoids in the family of catechins are well-defined small molecules that, if proven to possess immunomodulatory properties, hold promise as vaccine adjuvants and various therapies. In an effort to determine the in vivo immunomodulatory properties of these molecules, we found that although mucosal and systemic vaccinations with a recombinant HIV-1BaL gp120 with either a catechin, epigallo catechin gallate (EGCG) or pro-vitamin A (retinyl palmitate) alone in a vegetable-oil-in-water emulsion (OWE) suppressed antigen-specific responses, the combination of EGCG and vitamin A or E in OWE (Nutritive Immune-enhancing Delivery System, NIDS) synergistically enhanced adaptive B-cell, and CD4(+) and CD8(+) T-cell responses, following induction of relatively low local and systemic innate tumour necrosis factor-α (TNF-α), interleukin-6 (IL-6) and IL-17, but relatively high levels of early systemic IL-15 responses. For induction of adaptive interferon-γ and TNF-α responses by CD4(+) and CD8(+) T cells, the adjuvant effect of NIDS was dependent on both IL-15 and its receptor. In addition, the anti-oxidant activity of NIDS correlated positively with higher expression of the superoxide dismutase 1, an enzyme involved in reactive oxygen species elimination but negatively with secretion of IL-1β. This suggests that the mechanism of action of NIDS is dependent on anti-oxidant activity and IL-15, but independent of IL-1β and inflammasome formation. These data show that this approach in nutritive vaccine adjuvant design holds promise for the development of potentially safer effective vaccines. © 2016 John Wiley & Sons Ltd.

Neuroleptic-induced deficit syndrome in bipolar disorder with psychosis

PubMed Central

Ueda, Satoshi; Sakayori, Takeshi; Omori, Ataru; Fukuta, Hajime; Kobayashi, Takashi; Ishizaka, Kousuke; Saijo, Tomoyuki; Okubo, Yoshiro

2016-01-01

Neuroleptics can induce not only physical adverse effects but also mental effects that produce deficit status in thought, affect, cognition, and behavior. This condition is known as neuroleptic-induced deficit syndrome (NIDS), which includes apathy, lack of initiative, anhedonia, indifference, blunted affect, and reduced insight into disease. Although this old concept now appears almost forgotten, neuroleptics, whether typical or atypical, can make depression or bipolar disorder resemble other more refractory conditions, readily leading to mistaken diagnosis and inappropriate treatment. The authors describe three cases of NIDS superimposed on depressive phase in bipolar disorder with psychosis, where the attending psychiatrist’s failure to recognize NIDS prevented patients from receiving effective treatment and achieving remission. All cases achieved remission after reduction of neuroleptics and intensive therapy, including electroconvulsive therapy, for bipolar depression. The concept of NIDS was originally introduced for schizophrenia, and it has rarely been highlighted in other diseases. In recent years, however, atypical antipsychotics are being more often administered to patients with bipolar disorder. Psychiatrists, therefore, should also remember and exercise caution regarding NIDS in the pharmacotherapy of bipolar disorder with and without psychosis. The authors believe that the concept of NIDS needs to be reappraised in current psychiatry. PMID:26893564

[Evaluation of the National Vaccination Day in Bogota, D.C., 2001].

PubMed

Prieto Alvarado, Franklyn E; de la Hoz Restrepo, Fernando P

2003-01-01

A national immunization day-NID, aimed at improving vaccination coverage, was carried out in Colombia in November 2001. The main objective of the study was to measure the proportion of children under 2 years either completing their immunization schedule or advancing through it by receiving doses during the NID. Besides, we also evaluated the proportion of lost opportunities for vaccination during the NID and the impact of the media (TV, ratio, newspapers, etc.) in advertising the NID. In order to evaluate the impact of immunization a cross sectional survey was carried out in Bogotá in the waiting rows of the 30 randomly selected vaccination posts; 623 participants were systematically chosen. The outcomes were analyzed by age, socioeconomic level and type of health insurance-SSS. Only children holding a vaccination card were considered eligible for the study. Most people become aware about NID through TV, 81%, followed by radio advertisements, 22%. After attending NID the proportion of fully vaccinated children, according to PAHO scheme, raised from 46% to 66%, a 43% increase. This increase was even higher among children aged less than 6 months (140% increment). There were no differences in the increment by social stratum or affiliation to the SSS. Among the children studied we identified a 24% of loss opportunities for vaccination that did not differ by socioeconomic level or SSS groups. Our results suggest that, despite its high costs, NID might be useful to transiently overcome barriers for adequate access to health services.

Correlation of West Nile Virus Incidence in Donated Blood with West Nile Neuroinvasive Disease Rates, United States, 2010-2012.

PubMed

Betsem, Edouard; Kaidarova, Zhanna; Stramer, Susan L; Shaz, Beth; Sayers, Merlyn; LeParc, German; Custer, Brian; Busch, Michael P; Murphy, Edward L

2017-02-01

Over the past decade, West Nile virus (WNV) has spread across the United States. We aggregated blood donor data from 2010-2012 and then calculated the incidence of WNV RNA-positive donations and compared the incidence with neuroinvasive disease (NID) case data from the ArboNET surveillance system. Of 10,107,853 donations, 640 were confirmed positive. The seasonal WNV incidence rate per 100,000 persons was 33.4 (95% CI 22-45) in 2010, 25.7 (95% CI 15-34) in 2011, and 119.9 (95% CI 98-141) in 2012. NID to blood donor ratios were 1 in 164 (95% CI 152-178) in 2010, 1 in 158 (95% CI 145-174) in 2011, and 1 in 131 (95% CI 127-136) in 2012. We updated estimates of the ratio of NID to WNV infection rates, demonstrating stable disease penetrance over the study period. Blood donor WNV RNA screening is a valuable public health tool for WNV surveillance.

Testbed Environment for Distributed Observation (testbed omgeving voor gedistribueerde waarneming)

DTIC Science & Technology

2006-05-01

het IP-adres en portnumnmer van de MID halen . Ook de naamn van de XML-file om de NID te beschrijven staat hierin vermeld (in dit geval ’CSD.xmId’) in...DeviceML beschrijving van de NID op te halen . Dit wordt gedaan door een TCP/IP verbinding op te zetten tussen de LUS en de NID (via de DeviceML port...vernisenigvuidigd! enlof openbaar gensaaki door middel van druk, fotokopie, microftinm of op welke andere wijze dan ook, zonder voorafgaande schrifielijke

Nickel deficiency disrupts metabolism of ureides, amino acids, and organic acids of young pecan foliage.

PubMed

Bai, Cheng; Reilly, Charles C; Wood, Bruce W

2006-02-01

The existence of nickel (Ni) deficiency is becoming increasingly apparent in crops, especially for ureide-transporting woody perennials, but its physiological role is poorly understood. We evaluated the concentrations of ureides, amino acids, and organic acids in photosynthetic foliar tissue from Ni-sufficient (Ni-S) versus Ni-deficient (Ni-D) pecan (Carya illinoinensis [Wangenh.] K. Koch). Foliage of Ni-D pecan seedlings exhibited metabolic disruption of nitrogen metabolism via ureide catabolism, amino acid metabolism, and ornithine cycle intermediates. Disruption of ureide catabolism in Ni-D foliage resulted in accumulation of xanthine, allantoic acid, ureidoglycolate, and citrulline, but total ureides, urea concentration, and urease activity were reduced. Disruption of amino acid metabolism in Ni-D foliage resulted in accumulation of glycine, valine, isoleucine, tyrosine, tryptophan, arginine, and total free amino acids, and lower concentrations of histidine and glutamic acid. Ni deficiency also disrupted the citric acid cycle, the second stage of respiration, where Ni-D foliage contained very low levels of citrate compared to Ni-S foliage. Disruption of carbon metabolism was also via accumulation of lactic and oxalic acids. The results indicate that mouse-ear, a key morphological symptom, is likely linked to the toxic accumulation of oxalic and lactic acids in the rapidly growing tips and margins of leaflets. Our results support the role of Ni as an essential plant nutrient element. The magnitude of metabolic disruption exhibited in Ni-D pecan is evidence of the existence of unidentified physiological roles for Ni in pecan.

Correlation of West Nile Virus Incidence in Donated Blood with West Nile Neuroinvasive Disease Rates, United States, 2010–2012

PubMed Central

Betsem, Edouard; Kaidarova, Zhanna; Stramer, Susan L.; Shaz, Beth; Sayers, Merlyn; LeParc, German; Custer, Brian

2017-01-01

Over the past decade, West Nile virus (WNV) has spread across the United States. We aggregated blood donor data from 2010–2012 and then calculated the incidence of WNV RNA–positive donations and compared the incidence with neuroinvasive disease (NID) case data from the ArboNET surveillance system. Of 10,107,853 donations, 640 were confirmed positive. The seasonal WNV incidence rate per 100,000 persons was 33.4 (95% CI 22–45) in 2010, 25.7 (95% CI 15–34) in 2011, and 119.9 (95% CI 98–141) in 2012. NID to blood donor ratios were 1 in 164 (95% CI 152–178) in 2010, 1 in 158 (95% CI 145–174) in 2011, and 1 in 131 (95% CI 127–136) in 2012. We updated estimates of the ratio of NID to WNV infection rates, demonstrating stable disease penetrance over the study period. Blood donor WNV RNA screening is a valuable public health tool for WNV surveillance. PMID:27935796

Nickel Deficiency Disrupts Metabolism of Ureides, Amino Acids, and Organic Acids of Young Pecan Foliage[OA

PubMed Central

Bai, Cheng; Reilly, Charles C.; Wood, Bruce W.

2006-01-01

The existence of nickel (Ni) deficiency is becoming increasingly apparent in crops, especially for ureide-transporting woody perennials, but its physiological role is poorly understood. We evaluated the concentrations of ureides, amino acids, and organic acids in photosynthetic foliar tissue from Ni-sufficient (Ni-S) versus Ni-deficient (Ni-D) pecan (Carya illinoinensis [Wangenh.] K. Koch). Foliage of Ni-D pecan seedlings exhibited metabolic disruption of nitrogen metabolism via ureide catabolism, amino acid metabolism, and ornithine cycle intermediates. Disruption of ureide catabolism in Ni-D foliage resulted in accumulation of xanthine, allantoic acid, ureidoglycolate, and citrulline, but total ureides, urea concentration, and urease activity were reduced. Disruption of amino acid metabolism in Ni-D foliage resulted in accumulation of glycine, valine, isoleucine, tyrosine, tryptophan, arginine, and total free amino acids, and lower concentrations of histidine and glutamic acid. Ni deficiency also disrupted the citric acid cycle, the second stage of respiration, where Ni-D foliage contained very low levels of citrate compared to Ni-S foliage. Disruption of carbon metabolism was also via accumulation of lactic and oxalic acids. The results indicate that mouse-ear, a key morphological symptom, is likely linked to the toxic accumulation of oxalic and lactic acids in the rapidly growing tips and margins of leaflets. Our results support the role of Ni as an essential plant nutrient element. The magnitude of metabolic disruption exhibited in Ni-D pecan is evidence of the existence of unidentified physiological roles for Ni in pecan. PMID:16415214

Characterization of computer network events through simultaneous feature selection and clustering of intrusion alerts

NASA Astrophysics Data System (ADS)

Chen, Siyue; Leung, Henry; Dondo, Maxwell

2014-05-01

As computer network security threats increase, many organizations implement multiple Network Intrusion Detection Systems (NIDS) to maximize the likelihood of intrusion detection and provide a comprehensive understanding of intrusion activities. However, NIDS trigger a massive number of alerts on a daily basis. This can be overwhelming for computer network security analysts since it is a slow and tedious process to manually analyse each alert produced. Thus, automated and intelligent clustering of alerts is important to reveal the structural correlation of events by grouping alerts with common features. As the nature of computer network attacks, and therefore alerts, is not known in advance, unsupervised alert clustering is a promising approach to achieve this goal. We propose a joint optimization technique for feature selection and clustering to aggregate similar alerts and to reduce the number of alerts that analysts have to handle individually. More precisely, each identified feature is assigned a binary value, which reflects the feature's saliency. This value is treated as a hidden variable and incorporated into a likelihood function for clustering. Since computing the optimal solution of the likelihood function directly is analytically intractable, we use the Expectation-Maximisation (EM) algorithm to iteratively update the hidden variable and use it to maximize the expected likelihood. Our empirical results, using a labelled Defense Advanced Research Projects Agency (DARPA) 2000 reference dataset, show that the proposed method gives better results than the EM clustering without feature selection in terms of the clustering accuracy.

Sumoylation of the net inhibitory domain (NID) is stimulated by PIAS1 and has a negative effect on the transcriptional activity of Net.

PubMed

Wasylyk, Christine; Criqui-Filipe, Paola; Wasylyk, Bohdan

2005-01-27

Net (Elk-3, Sap-2, Erp) and the related ternary complex factors Elk-1 and Sap-1 are effectors of multiple signalling pathways at the transcriptional level and play a key role in the dynamic regulation of gene expression. Net is distinct from Elk-1 and Sap-1, in that it is a strong repressor of transcription that is converted to an activator by the Ras/Erk signalling pathway. Two autonomous repression domains of Net, the NID and the CID, mediate repression. We have previously shown that the co-repressor CtBP is implicated in repression by the CID. In this report we show that repression by the NID involves a different pathway, sumoylation by Ubc9 and PIAS1. PIAS1 interacts with the NID in the two-hybrid assay and in vitro. Ubc9 and PIAS1 stimulate sumoylation in vivo of lysine 162 in the NID. Sumoylation of lysine 162 increases repression by Net and decreases the positive activity of Net. These results increase our understanding of how one of the ternary complex factors regulates transcription, and contribute to the understanding of how different domains of a transcription factor participate in the complexity of regulation of gene expression.

Detection of complex cyber attacks

NASA Astrophysics Data System (ADS)

Gregorio-de Souza, Ian; Berk, Vincent H.; Giani, Annarita; Bakos, George; Bates, Marion; Cybenko, George; Madory, Doug

2006-05-01

One significant drawback to currently available security products is their inabilty to correlate diverse sensor input. For instance, by only using network intrusion detection data, a root kit installed through a weak username-password combination may go unnoticed. Similarly, an administrator may never make the link between deteriorating response times from the database server and an attacker exfiltrating trusted data, if these facts aren't presented together. Current Security Information Management Systems (SIMS) can collect and represent diverse data but lack sufficient correlation algorithms. By using a Process Query System, we were able to quickly bring together data flowing from many sources, including NIDS, HIDS, server logs, CPU load and memory usage, etc. We constructed PQS models that describe dynamic behavior of complicated attacks and failures, allowing us to detect and differentiate simultaneous sophisticated attacks on a target network. In this paper, we discuss the benefits of implementing such a multistage cyber attack detection system using PQS. We focus on how data from multiple sources can be combined and used to detect and track comprehensive network security events that go unnoticed using conventional tools.

[Neglected infectious diseases: an ongoing challenge for public health and equity in Peru].

PubMed

Cabezas-Sánchez, César

2014-04-01

Neglected Infectious Diseases (NID) affect more than one billion people worldwide, and are associated with poverty, geographic isolation of populations, social stigma, lack of precise data on estimates on both the global and local burden of disease (underreporting of the diseases), inadequate financial and political resources to effective control measures, lack of lobbying on behalf of the most vulnerable population, as well as scarce drug and diagnostic methods development. In this article we describe the relationship between NID, poverty and inequality, we propose a new concept of disease in the tropics, expanding the list of diseases that share characteristics with NID in the Peruvian context, discuss the limited availability of drugs and diagnostic tests to properly deal with these diseases, as well as highlight the contributions by the Peruvian National Institute of Health, and as final thoughts, we state that the solution for the prevention and control of NID must include an integrated approach, including the social determinants of health in the context of the fight against poverty and inequality.

Costs of polio immunization days in China: implications for mass immunization campaign strategies.

PubMed

Zhang, J; Yu, J J; Zhang, R Z; Zhang, X L; Zhou, J; Wing, J S; Schnur, A; Wang, K A

1998-01-01

Ten provinces of China were selected to estimate the cost per immunization of the 1994-95 national immunization days (NIDs) at five levels (e.g. province, prefecture, county, township and village). Personnel costs accounted for the largest overall share of costs (39 per cent), followed by publicity and promotion costs (27 per cent), and logistic costs (15 per cent). Without consideration of vaccine costs, the major part of NID expenses were shouldered at the township level, which paid for 47 per cent of all incremental costs, while county and village level covered 28 per cent and 18 per cent respectively. Estimation of average costs per immunization was 2.86 RMB yuan, or $0.34, including vaccine costs, buildings and equipment amortization and salaries at all levels. The factors affecting average cost of NID included the output volume, socio-economic development and geographic features. Various approaches were recommended: to intensify the productivity of time and staff, to employ alternative inexpensive manpower resources, to make the best use of publicity and social promotion, the expansion of the age groups and utilization of multi-intervention strategies. Good planning at township level was a decisive factor to ensure an effective NID conducted in an efficient manner. The average cost of China's NID was the lowest among all mass immunization campaigns ever documented. Much of the reduced average cost was attributable to economies of scale.

Management, regulation and environmental impacts of nitrogen fertilization in Northwestern Europe under the Nitrates Directive; a benchmark study

NASA Astrophysics Data System (ADS)

van Grinsven, H. J. M.; ten Berge, H. F. M.; Dalgaard, T.; Fraters, B.; Durand, P.; Hart, A.; Hofman, G.; Jacobsen, B. H.; Lalor, S. T. J.; Lesschen, J. P.; Osterburg, B.; Richards, K. G.; Techen, A.-K.; Vertès, F.; Webb, J.; Willems, W. J.

2012-06-01

Implementation of the Nitrates Directive (NiD) and its environmental impacts were compared for member states in the Northwest of the European Union (Ireland, UK, Denmark, The Netherlands, Belgium, Northern France and Germany). The main sources of data were national reports for the third reporting period for the NiD (2004-2007) and results of the MITERRA-EUROPE model. Implementation of the NiD in the considered member states is fairly comparable regarding restrictions for where and when to apply fertilizer and manure, but very different regarding application limits for N fertilization. Issues of concern and improvement of the implementation of the NiD are accounting for the fertilizer value of nitrogen in manure, and relating application limits for total nitrogen (N) to potential crop yield and N removal. The most significant environmental effect of the implementation of the NiD since 1995 is a major contribution to the decrease of the soil N balance (N surplus), particularly in Belgium, Denmark, Ireland, The Netherlands and the UK. This decrease is accompanied by a modest decrease of nitrate concentrations since 2000 in fresh surface waters in most countries. This decrease is less prominent for groundwater in view of delayed response of nitrate in deep aquifers. In spite of improved fertilization practices, the southeast of The Netherlands, the Flemish Region and Brittany remain to be regions of major concern in view of a combination of a high nitrogen surplus, high leaching fractions to groundwater and tenacious exceedance of the water quality standards. On average the gross N balance in 2008 for the seven member states in EUROSTAT and in national reports was about 20 kg N ha-1 lower than by MITERRA. The major cause is higher estimates of N removal in national reports which can amount to more than 50kg N ha-1. Differences between procedures in member states to assess nitrogen balances and water quality and a lack of cross boundary policy evaluations are handicaps when benchmarking the effectiveness of the NiD. This provides a challenge for the European Commission and its member states as the NiD remains an important piece of legislation for protecting drinking water quality in regions with many private or small public production facilities and controlling aquatic eutrophication from agricultural sources.

Management, regulation and environmental impacts of nitrogen fertilization in northwestern Europe under the Nitrates Directive; a benchmark study

NASA Astrophysics Data System (ADS)

van Grinsven, H. J. M.; ten Berge, H. F. M.; Dalgaard, T.; Fraters, B.; Durand, P.; Hart, A.; Hofman, G.; Jacobsen, B. H.; Lalor, S. T. J.; Lesschen, J. P.; Osterburg, B.; Richards, K. G.; Techen, A.-K.; Vertès, F.; Webb, J.; Willems, W. J.

2012-12-01

Implementation of the Nitrates Directive (NiD) and its environmental impacts were compared for member states in the northwest of the European Union (Ireland, United Kingdom, Denmark, the Netherlands, Belgium, Northern France and Germany). The main sources of data were national reports for the third reporting period for the NiD (2004-2007) and results of the MITERRA-EUROPE model. Implementation of the NiD in the considered member states is fairly comparable regarding restrictions for where and when to apply fertilizer and manure, but very different regarding application limits for N fertilization. Issues of concern and improvement of the implementation of the NiD are accounting for the fertilizer value of nitrogen in manure, and relating application limits for total nitrogen (N) to potential crop yield and N removal. The most significant environmental effect of the implementation of the NiD since 1995 is a major contribution to the decrease of the soil N balance (N surplus), particularly in Belgium, Denmark, Ireland, the Netherlands and the United Kingdom. This decrease is accompanied by a modest decrease of nitrate concentrations since 2000 in fresh surface waters in most countries. This decrease is less prominent for groundwater in view of delayed response of nitrate in deep aquifers. In spite of improved fertilization practices, the southeast of the Netherlands, the Flemish Region and Brittany remain to be regions of major concern in view of a combination of a high nitrogen surplus, high leaching fractions to groundwater and tenacious exceedance of the water quality standards. On average the gross N balance in 2008 for the seven member states in EUROSTAT and in national reports was about 20 kg N ha-1 yr-1 lower than by MITERRA. The major cause is higher estimates of N removal in national reports which can amount to more than 50 kg N ha-1 yr-1. Differences between procedures in member states to assess nitrogen balances and water quality and a lack of cross-boundary policy evaluations are handicaps when benchmarking the effectiveness of the NiD. This provides a challenge for the European Commission and its member states, as the NiD remains an important piece of legislation for protecting drinking water quality in regions with many private or small public production facilities and controlling aquatic eutrophication from agricultural sources.

Design and evaluation of a computed tomography (CT)-compatible needle insertion device using an electromagnetic tracking system and CT images.

PubMed

Shahriari, Navid; Hekman, Edsko; Oudkerk, Matthijs; Misra, Sarthak

2015-11-01

Percutaneous needle insertion procedures are commonly used for diagnostic and therapeutic purposes. Although current technology allows accurate localization of lesions, they cannot yet be precisely targeted. Lung cancer is the most common cause of cancer-related death, and early detection reduces the mortality rate. Therefore, suspicious lesions are tested for diagnosis by performing needle biopsy. In this paper, we have presented a novel computed tomography (CT)-compatible needle insertion device (NID). The NID is used to steer a flexible needle (φ0.55 mm) with a bevel at the tip in biological tissue. CT images and an electromagnetic (EM) tracking system are used in two separate scenarios to track the needle tip in three-dimensional space during the procedure. Our system uses a control algorithm to steer the needle through a combination of insertion and minimal number of rotations. Noise analysis of CT images has demonstrated the compatibility of the device. The results for three experimental cases (case 1: open-loop control, case 2: closed-loop control using EM tracking system and case 3: closed-loop control using CT images) are presented. Each experimental case is performed five times, and average targeting errors are 2.86 ± 1.14, 1.11 ± 0.14 and 1.94 ± 0.63 mm for case 1, case 2 and case 3, respectively. The achieved results show that our device is CT-compatible and it is able to steer a bevel-tipped needle toward a target. We are able to use intermittent CT images and EM tracking data to control the needle path in a closed-loop manner. These results are promising and suggest that it is possible to accurately target the lesions in real clinical procedures in the future.

Detecting DNA methylation of the BCL2, CDKN2A and NID2 genes in urine using a nested methylation specific polymerase chain reaction assay to predict bladder cancer.

PubMed

Scher, Michael B; Elbaum, Michael B; Mogilevkin, Yakov; Hilbert, David W; Mydlo, Jack H; Sidi, A Ami; Adelson, Martin E; Mordechai, Eli; Trama, Jason P

2012-12-01

Detection of methylated DNA has been shown to be a good biomarker for bladder cancer. Bladder cancer has the highest recurrence rate of any cancer and, as such, patients are regularly monitored using invasive diagnostic techniques. As urine is easily attainable, bladder cancer is an optimal cancer to detect using DNA methylation. DNA methylation is highly specific in cancer detection. However, it is difficult to detect because of the limited amount of DNA present in the urine of patients with bladder cancer. Therefore, an improved, sensitive and noninvasive diagnostic test is needed. We developed a highly specific and sensitive nested methylation specific polymerase chain reaction assay to detect the presence of bladder cancer in small volumes of patient urine. The genes assayed for DNA methylation are BCL2, CDKN2A and NID2. The regions surrounding the DNA methylation sites were amplified in a methylation independent first round polymerase chain reaction and the amplification product from the first polymerase chain reaction was used in a real-time methylation specific polymerase chain reaction. Urine samples were collected from patients receiving treatment at Wolfson Medical Center in Holon, Israel. In a pilot clinical study using patient urine samples we were able to differentiate bladder cancer from other urogenital malignancies and nonmalignant conditions with a sensitivity of 80.9% and a specificity of 86.4%. We developed a novel methylation specific polymerase chain reaction assay for the detection and monitoring of bladder cancer using DNA extracted from patient urine. The assay may also be combined with other diagnostic tests to improve accuracy. Copyright © 2012 American Urological Association Education and Research, Inc. Published by Elsevier Inc. All rights reserved.

Community-Acquired Poliovirus Infection in Children with Primary Immunodeficiencies in Tunisia

PubMed Central

Triki, Hinda; Barbouche, Mohamed Ridha; Bahri, Olfa; Bejaoui, Mohamed; Dellagi, Koussay

2003-01-01

The global polio eradication program recommends the use of massive vaccination campaigns with live vaccine through National Immunization Days (NIDs) to displace the wild virus from the community. Immunodeficient patients may be indirectly infected and become chronic excretors and potential reservoirs of polioviruses, a concern for the posteradication era. This prospective study aimed to assess the risk of community-acquired infection of immunodeficient patients following NIDs, the dynamics of viral excretion and the genetic variation of excreted viruses. Sixteen children with various primary immunodeficiencies, who did not receive the vaccine during the campaign, were investigated. Stool samples were collected weekly, shortly after the NIDs, during at least 3 months, and were processed for viral isolation. Isolates were characterized by three intratypic differentiation methods and partial sequencing of the VP1/2A region. Polioviruses were detected in 4 out of 16 patients (serotype 1 in 3 patients and serotype 3 in 1 patient). Sequencing revealed more than 99% homology with homotypic Sabin strains, suggesting recent infection. Duration of viral excretion ranged from 1 to 7 weeks. Nine out of eleven isolates from the three poliovirus serotype 1-infected patients disclosed a non-Sabin-like phenotype by enzyme-linked immunosorbent assay and had recurrent mutations within or close to the neutralizing antigenic sites. In summary, the risk of secondary infection in immunodeficient patients is within the range previously reported for the general population. Although none of the four infected patients developed prolonged viral excretion, particular viral variants were selected and may be of epidemiological significance. PMID:12624052

An Evaluation of the NIDS (registered trademark) ACE (trademark) Test

DTIC Science & Technology

2014-06-30

included chemicals commonly used for drinking water disinfection (chlorine and chloramine), byproducts of cyanobacteria blooms (geosmin and 2...duration field toxicity test for Army drinking water . One component of the ESB the ACE Test) is an enzymatic assay designed to detect neurotoxicants...adverse health effects is the presence of toxic industrial chemicals (TICs) in drinking water . The current field water test kit – the water quality

Poiseuille equation for steady flow of fractal fluid

NASA Astrophysics Data System (ADS)

Tarasov, Vasily E.

2016-07-01

Fractal fluid is considered in the framework of continuous models with noninteger dimensional spaces (NIDS). A recently proposed vector calculus in NIDS is used to get a description of fractal fluid flow in pipes with circular cross-sections. The Navier-Stokes equations of fractal incompressible viscous fluids are used to derive a generalization of the Poiseuille equation of steady flow of fractal media in pipe.

Response of PAH-degrading genes to PAH bioavailability in the overlying water, suspended sediment, and deposited sediment of the Yangtze River.

PubMed

Xia, Xinghui; Xia, Na; Lai, Yunjia; Dong, Jianwei; Zhao, Pujun; Zhu, Baotong; Li, Zhihuang; Ye, Wan; Yuan, Yue; Huang, Junxiong

2015-06-01

The degrading genes of hydrophobic organic compounds (HOCs) serve as indicators of in situ HOC degradation potential, and the existing forms and bioavailability of HOCs might influence the distribution of HOC-degrading genes in natural waters. However, little research has been conducted to study the relationship between them. In the present study, nahAc and nidA genes, which act as biomarkers for naphthalene- and pyrene-degrading bacteria, were selected as model genotypes to investigate the response of polycyclic aromatic hydrocarbon (PAH)-degrading genes to PAH bioavailability in the overlying water, suspended sediment (SPS), and deposited sediment of the Yangtze River. The freely dissolved concentration, typically used to reflect HOC bioavailability, and total dissolved, as well as sorbed concentrations of PAHs were determined. Phylogenetic analysis showed that all the PAH-ring hydroxylating dioxygenase gene sequences of Gram-negative bacteria (PAH-RHD[GN]) were closely related to nahAc, nagAc, nidA, and uncultured PAH-RHD genes. The PAH-RHD[GN] gene diversity as well as nahAc and nidA gene copy numbers decreased in the following order: deposited sediment>SPS>overlying water. The nahAc and nidA gene abundance was not significantly correlated with environmental parameters but was significantly correlated with the bioavailable existing forms of naphthalene and pyrene in the three phases. The nahAc gene copy numbers in the overlying water and deposited sediment were positively correlated with freely dissolved naphthalene concentrations in the overlying and pore water phases, respectively, and so were nidA gene copy numbers. This study suggests that the distribution and abundance of HOC-degrading bacterial population depend on the HOC bioavailability in aquatic environments. Copyright © 2015 Elsevier Ltd. All rights reserved.

Dimensional Analysis in Mathematical Modeling Systems: A Simple Numerical Method

DTIC Science & Technology

1991-02-01

US Army Ballistic Research Laboratories, Aberden Proving Ground , NID, August 1975. [18] Hi1irlimann, T., and .J. lKohlas "LPL: A Structured Language...such systems can prove that (a’ + ab + b2 + ba) = (a + b) 2 . With some effort, since the laws of physical algebra are a minor variant on those of

Methyl-CpG-binding protein 2 mediates antifibrotic effects in scleroderma fibroblasts.

PubMed

He, Ye; Tsou, Pei-Suen; Khanna, Dinesh; Sawalha, Amr H

2018-05-14

Emerging evidence supports a role for epigenetic regulation in the pathogenesis of scleroderma (SSc). We aimed to assess the role of methyl-CpG-binding protein 2 (MeCP2), a key epigenetic regulator, in fibroblast activation and fibrosis in SSc. Dermal fibroblasts were isolated from patients with diffuse cutaneous SSc (dcSSc) and from healthy controls. MeCP2 expression was measured by qPCR and western blot. Myofibroblast differentiation was evaluated by gel contraction assay in vitro. Fibroblast proliferation was analysed by ki67 immunofluorescence staining. A wound healing assay in vitro was used to determine fibroblast migration rates. RNA-seq was performed with and without MeCP2 knockdown in dcSSc to identify MeCP2-regulated genes. The expression of MeCP2 and its targets were modulated by siRNA or plasmid. Chromatin immunoprecipitation followed by sequencing (ChIP-seq) using anti-MeCP2 antibody was performed to assess MeCP2 binding sites within MeCP2-regulated genes. Elevated expression of MeCP2 was detected in dcSSc fibroblasts compared with normal fibroblasts. Overexpressing MeCP2 in normal fibroblasts suppressed myofibroblast differentiation, fibroblast proliferation and fibroblast migration. RNA-seq in MeCP2-deficient dcSSc fibroblasts identified MeCP2-regulated genes involved in fibrosis, including PLAU , NID2 and ADA . Plasminogen activator urokinase (PLAU) overexpression in dcSSc fibroblasts reduced myofibroblast differentiation and fibroblast migration, while nidogen-2 (NID2) knockdown promoted myofibroblast differentiation and fibroblast migration. Adenosine deaminase (ADA) depletion in dcSSc fibroblasts inhibited cell migration rates. Taken together, antifibrotic effects of MeCP2 were mediated, at least partly, through modulating PLAU, NID2 and ADA. ChIP-seq further showed that MeCP2 directly binds regulatory sequences in NID2 and PLAU gene loci. This study demonstrates a novel role for MeCP2 in skin fibrosis and identifies MeCP2-regulated genes associated with fibroblast migration, myofibroblast differentiation and extracellular matrix degradation, which can be potentially targeted for therapy in SSc. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

Increase of perceived frequency of neighborhood domestic violence is associated with increase of women's depression symptoms in a nationally representative longitudinal study in South Africa.

PubMed

Meffert, Susan M; McCulloch, Charles E; Neylan, Thomas C; Gandhi, Monica; Lund, Crick

2015-04-01

Studies that examine the effects of neighborhood characteristics on mental health show that perceptions of general neighborhood violence are associated with depression across diverse populations (Clark et al., 2008; Velez-Gomez et al., 2013; Wilson-Genderson & Pruchno, 2013). However, to our knowledge, none have examined the specific effect of perceived frequency of neighborhood domestic violence (PFNDV) on residents' mental health, despite knowledge that domestic violence is a potent predictor of depression at the level of the individual. This study investigates the impact of PFNDV on mental health using the South African National Income Dynamics Study (SA-NIDS). NIDS Waves 2 and 3 measure the perceived frequency of six neighborhood violence subtypes through the NIDS household respondent questionnaire and depression through a questionnaire administered to all NIDS participants. Linear regression was used to model the relationship between change in depression symptoms and change in violence subtypes between Waves 2 and 3. We found that two-year increase in PFNDV was significantly correlated with increase of depression symptoms over the same time period for women, independently of individual, household and neighborhood level characteristics, including five other types of neighborhood violence. No other type of violence was associated with increased depression in women in the fully adjusted model. Research and policy implications are discussed. Copyright © 2015 Elsevier Ltd. All rights reserved.

Comparison of patients with and without intellectual disability under general anesthesia: A retrospective study.

PubMed

Sitilci, T; Demirgan, S; Akcay, C; Kahraman, N; Koseoglu, B G; Erdem, M A; Cankaya, A B

2017-04-01

We analyzed and retrospectively compared patients with and without intellectual disability (ID) who underwent oral surgery under general anesthesia at Istanbul University, Faculty of Dentistry, Department of General Anesthesia, between October 2012 and June 2013 with regard to the following categories: Demographic features, American Society of Anesthesiologists (ASA) classification, Mallampati score, type of anesthetic drug used during the operation, type of intubation used, any difficulties with tracheal intubation, presence of systemic diseases, and recovery times after ending general anesthesia. A total of 348 patients were selected from the Department of Maxillofacial Surgery and the Department of Pedodontics who underwent surgery with general anesthesia. Medical histories of all patients were taken, and their electrocardiography, chest X-rays, complete blood count, and blood clotting tests were checked during a preoperative assessment. Mallampati evaluations were also performed. Patients were grouped into ASA I, II, or III according to the ASA classification and were treated under general anesthesia. There was no significant difference between normal and intellectually disabled patients in terms of gender, Mallampati scores, intubation difficulties, mean anesthetic period, time to discharge, or postoperative nausea and vomiting. Epilepsy and genetic diseases in intellectually disabled patients were significantly more common than in non-ID (NID) patients. However, the frequency of diabetes and chronic obstructive pulmonary disease in NID patients was significantly higher than in the intellectually disabled patients. Dental treatment of intellectually disabled patients under general anesthesia can be performed just as safely as that with NID patients.

Looking the cow in the eye: deletion in the NID1 gene is associated with recessive inherited cataract in Romagnola cattle.

PubMed

Murgiano, Leonardo; Jagannathan, Vidhya; Calderoni, Valerio; Joechler, Monika; Gentile, Arcangelo; Drögemüller, Cord

2014-01-01

Cataract is a known condition leading to opacification of the eye lens causing partial or total blindness. Mutations are known to cause autosomal dominant or recessive inherited forms of cataracts in humans, mice, rats, guinea pigs and dogs. The use of large-sized animal models instead of those using mice for the study of this condition has been discussed due to the small size of rodent lenses. Four juvenile-onset cases of bilateral incomplete immature nuclear cataract were recently observed in Romagnola cattle. Pedigree analysis suggested a monogenic autosomal recessive inheritance. In addition to the cataract, one of the cases displayed abnormal head movements. Genome-wide association and homozygosity mapping and subsequent whole genome sequencing of a single case identified two perfectly associated sequence variants in a critical interval of 7.2 Mb on cattle chromosome 28: a missense point mutation located in an uncharacterized locus and an 855 bp deletion across the exon 19/intron 19 border of the bovine nidogen 1 (NID1) gene (c.3579_3604+829del). RT-PCR showed that NID1 is expressed in bovine lenses while the transcript of the second locus was absent. The NID1 deletion leads to the skipping of exon 19 during transcription and is therefore predicted to cause a frameshift and premature stop codon (p.1164fs27X). The truncated protein lacks a C-terminal domain essential for binding with matrix assembly complexes. Nidogen 1 deficient mice show neurological abnormalities and highly irregular crystal lens alterations. This study adds NID1 to the list of candidate genes for inherited cataract in humans and is the first report of a naturally occurring mutation leading to non-syndromic catarct in cattle provides a potential large animal model for human cataract.

Raising parents' awareness of the benefits of immunization by using a visual aid tool.

PubMed

Mulumba, Jose Gaby Tshikuka; Daoud, Saada; Kabang, Bandé

2007-07-01

A visual aid tool was used in two communities of Chad to raise parents' awareness of the benefits of immunization. In one community, the tool was administered by social workers two weeks before national immunization days (NIDs) and in the other community by vaccinators during NIDs. Parents' awareness significantly rose in both communities but was more significant in the community where the tool was administered by social workers. A significant association was found between parents' unawareness and children who missed immunization in both communities.

Anisotropic CMB distortions from non-Gaussian isocurvature perturbations

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ota, Atsuhisa; Sekiguchi, Toyokazu; Tada, Yuichiro

2015-03-01

We calculate the CMB μ-distortion, (μ), and the angular power spectrum of its cross-correlation with the temperature anisotropy, (μT), in the presence of the non-Gaussian neutrino isocurvature density (NID) mode. While the pure Gaussian NID perturbations give merely subdominant contributions to (μ) and do not create (μT), we show large (μT) can be realized in case where, especially, the NID perturbations S(x) are proportional to the square of a Gaussian field g(x), i.e. S(x)∝ g{sup 2}(x). Such Gaussian-squared perturbations contribute to not only the power spectrum, but also the bispectrum of CMB anisotropies. The constraints from the power spectrum ismore » given by P{sub SS}(k{sub 0})∼P{sub g}{sup 2}(k{sub 0})∼<10{sup −10} at k{sub 0}=0.05 Mpc{sup −1}. We also forecast constraints from the CMB temperature and E-mode polarisation bispectra, and show that P{sub g}(k{sub 0})∼<10{sup −5} would be allowed from the Planck data. We find that (μ) and |l(l+1)C{sup μT}{sub l}| can respectively be as large as 10{sup −9} and 10{sup −14} with uncorrelated scale-invariant NID perturbations for P{sub g}(k{sub 0})=10{sup −5}. When the spectrum of the Gaussian field is blue-tilted (with spectral index n{sub g}≅1.5), (μT) can be enhanced by an order of magnitude.« less

The enrichment behavior of natural radionuclides in pulverized oil shale-fired power plants.

PubMed

Vaasma, Taavi; Kiisk, Madis; Meriste, Tõnis; Tkaczyk, Alan Henry

2014-12-01

The oil shale industry is the largest producer of NORM (Naturally Occurring Radioactive Material) waste in Estonia. Approximately 11-12 million tons of oil shale containing various amounts of natural radionuclides is burned annually in the Narva oil shale-fired power plants, which accounts for approximately 90% of Estonian electricity production. The radionuclide behavior characteristics change during the fuel combustion process, which redistributes the radionuclides between different ash fractions. Out of 24 operational boilers in the power plants, four use circulating fluidized bed (CFB) technology and twenty use pulverized fuel (PF) technology. Over the past decade, the PF boilers have been renovated, with the main objective to increase the efficiency of the filter systems. Between 2009 and 2012, electrostatic precipitators (ESP) in four PF energy blocks were replaced with novel integrated desulphurization technology (NID) for the efficient removal of fly ash and SO2 from flue gases. Using gamma spectrometry, activity concentrations and enrichment factors for the (238)U ((238)U, (226)Ra, (210)Pb) and (232)Th ((232)Th, (228)Ra) family radionuclides as well as (40)K were measured and analyzed in different PF boiler ash fractions. The radionuclide activity concentrations in the ash samples increased from the furnace toward the back end of the flue gas duct. The highest values in different PF boiler ash fractions were in the last field of the ESP and in the NID ash, where radionuclide enrichment factors were up to 4.2 and 3.3, respectively. The acquired and analyzed data on radionuclide activity concentrations in different PF boiler ashes (operating with an ESP and a NID system) compared to CFB boiler ashes provides an indication that changes in the fuel (oil shale) composition and boiler working parameters, as well as technological enhancements in Estonian oil shale fired power plants, have had a combined effect on the distribution patterns of natural radionuclides in the oil shale combustion products. Copyright © 2014 Elsevier Ltd. All rights reserved.

Constraints on isocurvature models from the WMAP first-year data

DOE Office of Scientific and Technical Information (OSTI.GOV)

Moodley, K.; Astrophysics, University of Oxford, Denys Wilkinson Building, Keble Road, Oxford OX1 3RH; Bucher, M.

2004-11-15

We investigate the constraints imposed by the first-year Wilkinson Microwave Anisotropy Probe (WMAP) cosmic microwave background (CMB) data extended to higher multipoles by data from ACBAR, BOOMERANG, CBI, and the VSA and by the large-scale structure data from the 2dF galaxy redshift survey on the possible amplitude of primordial isocurvature modes. A flat universe with cold dark matter (CDM) and cosmological constant {lambda} is assumed, and the baryon, CDM isocurvature (CI), and neutrino density (NID), and velocity (NIV) isocurvature modes are considered. Constraints on the allowed isocurvature contributions are established from the data for various combinations of the adiabatic modemore » and one, two, and three isocurvature modes, with intermode cross correlations allowed. Since baryon and CDM isocurvature are observationally virtually indistinguishable, these modes are not considered separately. We find that when just a single isocurvature mode is added, the present data allows an isocurvature fraction, in terms of the nonadiabatic contribution to the power in the CMB anisotropy, as large as 13{+-}6, 7{+-}4, and 13{+-}7 percent for adiabatic plus the CI, NID, and NIV modes, respectively. When two isocurvature modes plus the adiabatic mode and cross correlations are allowed, these percentages rise to 47{+-}16, 34{+-}12, and 44{+-}12 for the combinations CI+NID, CI+NIV, and NID+NIV, respectively. Finally, when all three isocurvature modes and cross correlations are allowed, the admissible isocurvature fraction rises to 57{+-}9 percent. In our analysis we consider only scalar modes with a single common tilt parameter for all the modes and do not consider any possible primordial anisotropies in the local neutrino velocity distribution beyond quadrupole order. The sensitivity of the results to the choice of prior probability distribution is examined.« less

Activation cross sections of the 64Ni(d,2n) reaction for the production of the medical radionuclide 64Cu

NASA Astrophysics Data System (ADS)

Hermanne, A.; Tárkányi, F.; Takács, S.; Kovalev, S. F.; Ignatyuk, A.

2007-05-01

Deuteron particle induced reactions for generation of 64Cu used in diagnostic and therapeutic nuclear medicine and its possible short lived contaminant 61Cu were investigated with the stacked foil activation technique on natural nickel targets up to Ed = 20.5 MeV. Excitation functions for the reactions 64Ni(d,2n) 64Cu and natNi(d, x) 61Cu are obtained by gamma spectroscopy and are compared with earlier literature values. Thick target yields have been deduced from the experimental cross sections and the predictive capability of the ALICE-IPPE, EMPIRE II and GNASH model codes is tested.

[The road to elimination: an overview of neglected infectious diseases in Latin America and the Caribbean].

PubMed

Ault, Steven Kenyon; Catalá Pascual, Laura; Grados-Zavala, Maria Elena; Gonzálvez García, Guillermo; Castellanos, Luis Gerardo

2014-04-01

Neglected infectious diseases (NID) affect mainly isolated populations living in isolation and in poor socioeconomic conditions. These diseases, by their chronic and silent nature, often affect communities with a weak political voice. This translates into very little attention or political priority; which is reflected in minimal and insufficient preventive measures, monitoring and control. However, there is evidence this situation is changing favorably in some countries of the Americas. In recent years, several resolutions (official agreement of the member countries of the Pan American Health Organization / World Health Organization-PAHO / WHO), regional and global agreements on public health; with a greater commitment from the pharmaceutical industry, and other donors and international partners in combination with the development and use of integrated action plans have allowed countries to intensify public interventions to control these diseases and thus achieve target elimination of NID. Onchocerciasis, lymphatic filariasis, Chagas disease, leprosy and trachoma blindness, among others, have been eliminated in several countries and endemic areas, regardless of the level of development of the country or geographical area where they are located. The political decision reflected in adequate financial resources in the next decade will be crucial to achieving the goals of elimination of NID (regional and national).

Net (ERP/SAP2) one of the Ras-inducible TCFs, has a novel inhibitory domain with resemblance to the helix-loop-helix motif.

PubMed Central

Maira, S M; Wurtz, J M; Wasylyk, B

1996-01-01

The three ternary complex factors (TCFs), Net (ERP/ SAP-2), ELK-1 and SAP-1, are highly related ets oncogene family members that participate in the response of the cell to Ras and growth signals. Understanding the different roles of these factors will provide insights into how the signals result in coordinate regulation of the cell. We show that Net inhibits transcription under basal conditions, in which SAP-1a is inactive and ELK-1 stimulates. Repression is mediated by the NID, the Net Inhibitory Domain of about 50 amino acids, which autoregulates the Net protein and also inhibits when it is isolated in a heterologous fusion protein. Net is particularly sensitive to Ras activation. Ras activates Net through the C-domain, which is conserved between the three TCFs, and the NID is an efficient inhibitor of Ras activation. The NID, as well as more C-terminal sequences, inhibit DNA binding. Net is more refractory to DNA binding than the other TCFs, possibly due to the presence of multiple inhibitory elements. The NID may adopt a helix-loop-helix (HLH) structure, as evidenced by homology to other HLH motifs, structure predictions, model building and mutagenesis of critical residues. The sequence resemblance with myogenic factors suggested that Net may form complexes with the same partners. Indeed, we found that Net can interact in vivo with the basic HLH factor, E47. We propose that Net is regulated at the level of its latent DNA-binding activity by protein interactions and/or phosphorylation. Net may form complexes with HLH proteins as well as SRF on specific promotor sequences. The identification of the novel inhibitory domain provides a new inroad into exploring the different roles of the ternary complex factors in growth control and transformation. Images PMID:8918463

Endothelial dysfunction, abnormal vascular structure and lower urinary tract symptoms in men and women.

PubMed

Matsui, Shogo; Kajikawa, Masato; Maruhashi, Tatsuya; Iwamoto, Yumiko; Oda, Nozomu; Kishimoto, Shinji; Hashimoto, Haruki; Hidaka, Takayuki; Kihara, Yasuki; Chayama, Kazuaki; Hida, Eisuke; Goto, Chikara; Aibara, Yoshiki; Nakashima, Ayumu; Yusoff, Farina Mohamad; Noma, Kensuke; Kuwahara, Yoshitaka; Matsubara, Akio; Higashi, Yukihito

2018-06-15

Lower urinary tract symptoms (LUTS) is not only common symptoms in elderly men and women but also risk of future cardiovascular events. The purpose of this study was to evaluate the relationships of vascular function and structure with LUTS in men and women. We investigated flow-mediated vasodilation (FMD) and nitroglycerine-induced vasodilation (NID) as vascular function, brachial-ankle pulse wave velocity (baPWV) as vascular structure, and LUTS assessed by International Prostate Symptom Score (IPSS) in 287 men and 147 women. IPSS was significantly correlated with traditional cardiovascular risk factors, Framingham risk score, FMD, NID and baPWV. Moderate to severe LUTS was associated with the prevalence of coronary heart disease in men but not in women. In men, FMD and NID were significantly lower in the moderate to severe LUTS group than in the none to mild LUTS group (2.1 ± 2.0% vs. 4.0 ± 3.0% and 9.3 ± 6.1% vs. 12.8 ± 6.6%, P < 0.001, respectively). baPWV was significantly higher in the moderate to severe LUTS group than in the none to mild LUTS group (1722 ± 386 cm/s vs. 1509 ± 309 cm/s, P < 0.001). In multivariate analysis, FMD was independently associated with a decrease in the odds ratio of moderate to severe LUTS in men (OR: 0.83, 95% CI, 0.72-0.95; P = 0.008) but not in women. NID and baPWV were not independently associated with moderate to severe LUTS either in men or women. These findings suggest that endothelial dysfunction is associated with LUTS in men. LUTS in men may be useful for a predictor of cardiovascular events. URL for Clinical Trial: http://UMIN; Registration Number for Clinical Trial: UMIN000003409. Copyright © 2018 Elsevier B.V. All rights reserved.

Net (ERP/SAP2) one of the Ras-inducible TCFs, has a novel inhibitory domain with resemblance to the helix-loop-helix motif.

PubMed

Maira, S M; Wurtz, J M; Wasylyk, B

1996-11-01

The three ternary complex factors (TCFs), Net (ERP/ SAP-2), ELK-1 and SAP-1, are highly related ets oncogene family members that participate in the response of the cell to Ras and growth signals. Understanding the different roles of these factors will provide insights into how the signals result in coordinate regulation of the cell. We show that Net inhibits transcription under basal conditions, in which SAP-1a is inactive and ELK-1 stimulates. Repression is mediated by the NID, the Net Inhibitory Domain of about 50 amino acids, which autoregulates the Net protein and also inhibits when it is isolated in a heterologous fusion protein. Net is particularly sensitive to Ras activation. Ras activates Net through the C-domain, which is conserved between the three TCFs, and the NID is an efficient inhibitor of Ras activation. The NID, as well as more C-terminal sequences, inhibit DNA binding. Net is more refractory to DNA binding than the other TCFs, possibly due to the presence of multiple inhibitory elements. The NID may adopt a helix-loop-helix (HLH) structure, as evidenced by homology to other HLH motifs, structure predictions, model building and mutagenesis of critical residues. The sequence resemblance with myogenic factors suggested that Net may form complexes with the same partners. Indeed, we found that Net can interact in vivo with the basic HLH factor, E47. We propose that Net is regulated at the level of its latent DNA-binding activity by protein interactions and/or phosphorylation. Net may form complexes with HLH proteins as well as SRF on specific promotor sequences. The identification of the novel inhibitory domain provides a new inroad into exploring the different roles of the ternary complex factors in growth control and transformation.

Experimental study of the 66Ni(d ,p ) 67Ni one-neutron transfer reaction

NASA Astrophysics Data System (ADS)

Diriken, J.; Patronis, N.; Andreyev, A.; Antalic, S.; Bildstein, V.; Blazhev, A.; Darby, I. G.; De Witte, H.; Eberth, J.; Elseviers, J.; Fedosseev, V. N.; Flavigny, F.; Fransen, Ch.; Georgiev, G.; Gernhauser, R.; Hess, H.; Huyse, M.; Jolie, J.; Kröll, Th.; Krücken, R.; Lutter, R.; Marsh, B. A.; Mertzimekis, T.; Muecher, D.; Orlandi, R.; Pakou, A.; Raabe, R.; Randisi, G.; Reiter, P.; Roger, T.; Seidlitz, M.; Seliverstov, M.; Sotty, C.; Tornqvist, H.; Van De Walle, J.; Van Duppen, P.; Voulot, D.; Warr, N.; Wenander, F.; Wimmer, K.

2015-05-01

The quasi-SU(3) sequence of the positive parity ν g9 /2,d5 /2,s1 /2 orbitals above the N =40 shell gap are assumed to induce strong quadrupole collectivity in the neutron-rich Fe (Z =26 ) and Cr (Z =24 ) isotopes below the nickel region. In this paper the position and strength of these single-particle orbitals are characterized in the neighborhood of 68Ni (Z =28 ,N =40 ) through the 66Ni(d ,p )67Ni one-neutron transfer reaction at 2.95 MeV/nucleon in inverse kinematics, performed at the REX-ISOLDE facility in CERN. A combination of the Miniball γ -array and T-REX particle-detection setup was used and a delayed coincidence technique was employed to investigate the 13.3-μ s isomer at 1007 keV in 67Ni. Excited states up to an excitation energy of 5.8 MeV have been populated. Feeding of the ν g9 /2 (1007 keV) and ν d5 /2 (2207 keV and 3277 keV) positive-parity neutron states and negative parity (ν p f ) states have been observed at low excitation energy. The extracted relative spectroscopic factors, based on a distorted-wave Born approximation analysis, show that the ν d5 /2 single-particle strength is mostly split over these two excited states. The results are also compared to the distribution of the proton single-particle strength in the 90Zr region (Z =40 ,N =50 ) .

Using oral polio vaccine beyond the cold chain: a feasibility study conducted during the national immunization campaign in Mali.

PubMed

Halm, Ariane; Yalcouyé, Idrissa; Kamissoko, Mady; Keïta, Tenemakan; Modjirom, Ndoutabé; Zipursky, Simona; Kartoglu, Umit; Ronveaux, Olivier

2010-04-26

We conducted the first systematic documentation of using oral polio vaccine (OPV) out of the cold chain during national immunization day (NID) campaigns in Mali. Using a crossover intervention design, vaccinators compared the transport of OPV in vaccine carriers with or without ice packs. Vaccine integrity was assured through monitoring vaccine vial monitor (VVM) status. Despite ambient temperatures up to 40 degrees C, none of the VVMs on any of the vials used (n=956) reached their discard point. Over 90% of vaccinators and supervisors preferred conducting NIDs without ice packs. In addition, using OPV out of the cold chain reduced vaccine wastage resulting from melting ice packs causing labels to detach from the vial. Copyright 2010 Elsevier Ltd. All rights reserved.

75 FR 17305 - National Industrial Security Program Directive No. 1

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-06

... Top Secret; Communications Security, except classified keys used for data transfer; Restricted Data... clearance under an SSA to Top Secret unless an approved NID covering the prospective Top Secret access has...

Regulation of TCF ETS-domain transcription factors by helix-loop-helix motifs.

PubMed

Stinson, Julie; Inoue, Toshiaki; Yates, Paula; Clancy, Anne; Norton, John D; Sharrocks, Andrew D

2003-08-15

DNA binding by the ternary complex factor (TCF) subfamily of ETS-domain transcription factors is tightly regulated by intramolecular and intermolecular interactions. The helix-loop-helix (HLH)-containing Id proteins are trans-acting negative regulators of DNA binding by the TCFs. In the TCF, SAP-2/Net/ERP, intramolecular inhibition of DNA binding is promoted by the cis-acting NID region that also contains an HLH-like motif. The NID also acts as a transcriptional repression domain. Here, we have studied the role of HLH motifs in regulating DNA binding and transcription by the TCF protein SAP-1 and how Cdk-mediated phosphorylation affects the inhibitory activity of the Id proteins towards the TCFs. We demonstrate that the NID region of SAP-1 is an autoinhibitory motif that acts to inhibit DNA binding and also functions as a transcription repression domain. This region can be functionally replaced by fusion of Id proteins to SAP-1, whereby the Id moiety then acts to repress DNA binding in cis. Phosphorylation of the Ids by cyclin-Cdk complexes results in reduction in protein-protein interactions between the Ids and TCFs and relief of their DNA-binding inhibitory activity. In revealing distinct mechanisms through which HLH motifs modulate the activity of TCFs, our results therefore provide further insight into the role of HLH motifs in regulating TCF function and how the inhibitory properties of the trans-acting Id HLH proteins are themselves regulated by phosphorylation.

Models and Analogues for the Evaluation of Human Biodynamic Response, Performance and Protection

DTIC Science & Technology

1979-06-01

but in a point situated more ventrally . Nid-sagittal sacral curvature, length-width proportions and the height of the mid-sagittal curvature are...principal moments of che new ellipsoid are then calculated. I* , ioV- cm2 275 a:.s 1.981Iola - 82.99 225 175 125 75- 50 75 100 12S , S5 O75 Ix.,, to...along and three angulations about the three axes of the coordinate system. The complete descrip- tion of the behavior of a FSU can be obtained by

NID: ceasefire for the future.

PubMed

Tugbo, L P

1993-01-01

The goals of National Immunization Day (NID), which is held twice a year in the Philippines, include polio vaccination of all children less than 5 years of age, measles vaccination of all children aged 9 to 24 months, tetanus immunization of women aged 15 to 44 years, and vitamin A supplementation for all children under 5 years of age. This is in response to a World Declaration of the Survival, Protection, and Development of Children and a Plan of Action for the 1990s that were issued by the World Summit for Children (New York; September, 1990). The Plan has 7 major and 26 supporting goals. 3 of the goals, which are to be achieved by the end of the century, relate to micronutrient malnutrition and are as follows: 1) elimination of vitamin A deficiency disorders, 2) elimination of iodine deficiency disorders, and 3) reduction of iron deficiency anemia by 1/3. Another conference, "Ending Hidden Hunger", (Montreal, Canada; October, 1991) focused on the means and resources necessary to overcome micronutrient malnutrition. Health Secretary Juan Flavier utilized the mass media for the 1993 campaign. The messages emphasized in the campaign included 1) polio kills or cripples children for life; 2) vaccination with oral polio vaccine (OPV) is easily performed and prevents the disease without pain or injection; 3) NIDs will be held on every 3rd Wednesday of April and May from 1993 to 1995; 4) all children 0-59 months and all women 15 to 44 years are required to attend, even if previously immunized; 5) OPV given to a fully immunized child will boost immunity; 6) the Philippines will be free from polio by 1995 if all children ages 0-59 months are vaccinated on the NIDs; and 7) the participation of all filipinos is necessary to eradicate polio. Information, education, and communication (IEC) materials were distributed 2 weeks before the NID. Posters were placed in strategic government facilities, leaflets were distributed to mothers, and streamers were installed on the exterior of facilities. Immunization posts were established at all government health facilities (hospitals, lying-in centers, and barangay health stations), as well as at temporary sites at market places, shopping areas, schools, sports areas, bus and train stations, airports, and light rail transit stations. There were 2 types of posts; OPV, and EPI for measles vaccine and tetanus toxoid. The latter were staffed by trained health personnel. OPV and vitamin A were administered by nonhealth personnel, who were also part of mobile vaccination teams. Government agencies, nongovernmental organizations, international organizations, and the communities worked together. The Nutrition Center of the Philippines (NCP) staffed immunization posts in areas with NCP projects. Earlier, they had prepared lists of children, conducted orientation meetings, provided information on vitamin A, and arranged for site logistics. They provided vitamin A capsules and OPV to 1392 children.

"Data Acquisition Systems"

DOE Office of Scientific and Technical Information (OSTI.GOV)

Unterweger, Michael; Costrell, Louis deceased

2009-07-07

This project involved support for Lou Costrell and myself in the development of IEEE and IEC standards for nuclear counting and data acquisition systems. Over the years, as a result of this support, Lou and I were able to attend standards meetings of IEEE and IEC, which led directly to the publication of many standards for NIM systems, FastBus and CAMAC. We also chaired several writing committees as well as ANSI N42 (Nuclear instrumentation), IEEE NIM (NIM standard), IEEE NID (NPSS nuclear instruments and detector) and IEC TC45 WG9 (Nuclear instrumentation). Through this support we were able to assure thatmore » the interests of the US and DOE were expressed and implemented in the various standards.« less

Maintaining high vitamin A supplementation coverage in children: lessons from Niger.

PubMed

Aguayo, Victor M; Baker, Shawn K; Crespin, Xavier; Hamani, Harouna; MamadoulTaïbou, Aissa

2005-03-01

In 1997, the reduction of child mortality became a policy priority for the Government of Niger because Niger's child mortality rate was the highest in the world. The Ministry of Public Health, Helen Keller International (HKI), and UNICEF spearheaded a coalition-building process linking vitamin A deficiency (VAD) control to national child survival goals. An evidence-based advocacy strategy was developed around the child survival benefits of adequate and sustained VAD control with one unambiguous message: "VAD control can avert over 25,000 child deaths per year." As a result, in 1997 Niger became one of the first countries in Africa to effectively integrate vitamin A supplementation into National Immunization Days (NIDs) for polio eradication. The challenge was then to provide children with a second annual dose of vitamin A. This led in 1999 to the first ever National Micronutrient Days (NMDs) in Africa. NMDs are mobilization campaigns in which caregivers are actively encouraged to take their children for the delivery of vitamin A supplements. Since 1999, the combination of NIDs and NMDs has ensured that over 80% of children 6 to 59 months of age receive two vitamin A doses annually. The success of NIDs/NMDs has relied on five pillars: leadership and ownership by the Ministry of Public Health; district-level planning and implementation; effective training and flexible delivery mechanisms; effective social information, communication, and mobilization; and responsiveness and flexibility of Ministry of Public Health and development partners. This successful approach has been widely disseminated, notably through the West African Nutrition Focal Points Network.

Feedback to providers improves evidence-based implantable cardioverter-defibrillator programming and reduces shocks.

PubMed

Silver, Marc T; Sterns, Laurence D; Piccini, Jonathan P; Joung, Boyoung; Ching, Chi-Keong; Pickett, Robert A; Rabinovich, Rafael; Liu, Shufeng; Peterson, Brett J; Lexcen, Daniel R

2015-03-01

Implantable cardioverter-defibrillator (ICD) shocks are associated with increased anxiety, health care utilization, and potentially mortality. The purpose of the Shock-Less Study was to determine if providing feedback reports to physicians on their adherence to evidence-based shock reduction programming could improve their programming behavior and reduce shocks. Shock-Less enrolled primary prevention (PP) and secondary prevention (SP) ICD patients between 2009 and 2012 at 118 study centers worldwide and followed patients longitudinally after their ICD implant. Center-specific therapy programming reports (TPRs) were delivered to each center 9 to 12 months after their first enrollment. The reports detailed adherence to evidence-based programming targets: number of intervals to detect ventricular fibrillation (VF NID), longest treatment interval (LTI), supraventricular tachycardia (SVT) discriminators (Wavelet, PR Logic), SVT limit, Lead Integrity Alert (LIA), and antitachycardia pacing (ATP). Clinicians programmed ICDs at their discretion. The primary outcome measure was the change in utilization of evidence-based shock reduction programming before (phase I, n = 2694 patients) and after initiation of the TPR (phase II, n = 1438 patients). Patients implanted after feedback reports (phase II) were up to 20% more likely to have their ICDs programmed in line with evidence-based shock reduction programming (eg, VF NID in PP patients 30/40 in 33.5% vs 18.6%, P < .0001). Patients implanted in phase II had a lower risk of all-cause shock (adjusted hazard ratio 0.72, 95% confidence interval 0.58-0.90, P = .003). Providing programming feedback reports improves adherence to evidence-based shock reduction programming and is associated with lower risk of ICD shocks. Copyright © 2015 Heart Rhythm Society. Published by Elsevier Inc. All rights reserved.

An epigenetic marker panel for recurrence risk prediction of low grade papillary urothelial cell carcinoma (LGPUCC) and its potential use for surveillance after transurethral resection using urine

PubMed Central

Michailidi, Christina; Munari, Enrico; Driscoll, Tina; Schultz, Luciana; Bivalacqua, Trinity; Schoenberg, Mark; Sidransky, David; Netto, George J; Hoque, Mohammad Obaidul

2014-01-01

By a candidate gene approach, we analyzed the promoter methylation (PM) of 8 genes (ARF, TIMP3, RAR-β2, NID2, CCNA1, AIM1, CALCA and CCND2) by quantitative methylation specific PCR (QMSP) in the DNA of 17 non-recurrent and 19 recurrent noninvasive low grade papillary urothelial cell carcinoma (LGPUCC) archival tissues. Among the genes tested, by establishing an empiric cutoff value, CCND2, CCNA1, NID2, and CALCA showed higher frequency of methylation in recurrent than in non-recurrent LGPUCC: CCND2 10/19 (53%) vs. 2/17 (12%) (p=0.014); CCNA1 11/19 (58%) vs. 4/17 (23.5%) (p=0.048); NID2 13/19 (68%) vs. 3/17 (18%) (p=0.003) and CALCA 10/19 (53%) vs. 4/17 (23.5%) (p=0.097), respectively. We further analyzed PM of CCND2, CCNA1, and CALCA in urine DNA from UCC patients including LGPUCC and controls. The frequency of CCND2, CCNA1, and CALCA was significantly higher (p<0.0001) in urine of UCC cases [38/148 (26%), 50/73 (68%) and 94/148 (63.5%) respectively] than controls [0/56 (0%), 10/60 (17%) and 16/56 (28.5%), respectively)]. Most importantly we found at least one of the 3 markers were methylated positive in 25 out of 30 (83%) cytology negative LGPUCC cases. We also explored the biological function of CCNA1 in UCC. Prospective confirmatory studies are needed to develop a reliable tool for prediction of recurrence using primary LGPUCC tissues and/or urine. PMID:24980822

Effect of zinc imprinting and replacing inorganic zinc with organic zinc on early performance of broiler chicks

PubMed Central

Timmons, J.; Ao, T.; Paul, M.; Macalintal, L.; Pescatore, A.; Cantor, A.; Ford, M.; Dawson, K. A.

2017-01-01

Abstract The goal of this study was to determine the effects of feeding a zinc (Zn) deficient diet to broiler chicks for 96 h post-hatch followed by feeding diets with different Zn sources and supplemental levels (5 to 21 d) on the growth performance, tissue, and excreta Zn content. At the start of the study, four hundred 20-day-old male broiler chicks were divided into two groups. One group was fed a corn soybean meal based diet containing 25 mg of Zn/kg (imprinting diet, ID). The second group was fed the basal diet supplemented with 40 mg of Zn/kg from Zn oxide (ZnO) (non-imprinting diet, NID). Both groups were fed these diets for 96 h. At d 5, chicks from each group were randomly assigned to the dietary treatments consisting of the basal diet alone or the basal diet supplemented with 8 or 40 mg/kg Zn as ZnO or Zn proteinate. Main effects of post-hatch Zn ID were observed on feed intake and G:F. ID decreased (P < 0.05) feed intake and improved (P < 0.05) the gain to feed ratio (G:F) of 14 and 21 d old chicks compared to G:F of chicks fed NID. Additionally, G:F for 14 and 21 d was improved (P < 0.05) by interaction of Zn source × level. Furthermore, at d 21 chicks fed the ID had a lower (P < 0.05) Zn content in the tibia ash and excreta, and a higher (P < 0.05) Zn content in the pancreas tissue compared to chicks fed NID. These results suggest that Zn imprinting can affect body Zn stores and early performance. PMID:27664197

Bioinspired Non-iridescent Structural Color from Polymer Blend Thin Films

NASA Astrophysics Data System (ADS)

Nallapaneni, Asritha; Shawkey, Matthew; Karim, Alamgir

Colors exhibited in biological species are either due to natural pigments, sub-micron structural variation or both. Structural colors thus exhibited can be iridescent (ID) or non-iridescent (NID) in nature. NID colors originate due to interference and coherent scattering of light with quasi-ordered micro- and nano- structures. Specifically, in Eastern Bluebird (Sialia sialis) these nanostructures develop as a result of phase separation of β-keratin from cytoplasm present in cells. We replicate these structures via spinodal blend phase separation of PS-PMMA thin films. Colors of films vary from ultraviolet to blue. Scattering of UV-visible light from selectively leeched phase separated blends are studied in terms of varying domain spacing (200nm to 2 μm) of film. We control these parameters by tuning annealing time and temperature. Angle-resolved spectroscopy studies suggest that the films are weakly iridescent and scattering from phase-separated films is more diffused when compared to well-mixed films. This study offers solutions to several color-based application in paints and coatings industry.

Network Intrusion Dataset Assessment

DTIC Science & Technology

2013-03-01

Security, 6(1):173–180, October 2009. abs/0911.0787. 70 • Jungsuk Song, Hiroki Takakura, Yasuo Okabe, and Koji Nakao. “Toward a more practical...Inoue, and Koji Nakao. “Statistical analysis of honeypot data and building of Kyoto 2006+ dataset for NIDS evaluation”. BADGERS ’11: Proceedings of

Manual of Documentation Practices Applicable to Defence-Aerospace Scientific and Technical Information. Volume 3. Section 7 - Information Retrieval. Section 8 - Dissemination Practices. Section 9 - Microform Systems and Reprography

DTIC Science & Technology

1980-10-01

Location Flowchart has been drawn up to give guidance as to where to apply for various categories of reports. It also serves as an aid in deciding whether...or further disclosure S.l-. 72 NOTES 1. The flowchart is not intended to cover all possibilities; the following points are made for your guidance. 2...not followed the flowchart correctly - start again from ’BEGIN’. NEI N ’"A. 7-.1 %. 73 REPORT LOCATION BEGIN~ FLOWCHART rreporto aD-P.orriBR6N~I-D ubr

Pb-210 and Po-210 atmospheric releases via fly ash from oil shale-fired power plants.

PubMed

Vaasma, Taavi; Loosaar, Jüri; Gyakwaa, Francis; Kiisk, Madis; Özden, Banu; Tkaczyk, Alan H

2017-03-01

During high temperature processes in the furnace volatile and semi-volatile elements and radionuclides are partially emitted to the environment, depending on their chemical form in the original fuel, the technological set-up of the combustion system, and the prevailing combustion conditions. Two of the world's largest oil shale-fired power plants (PPs) have been operational in Estonia from the 1960s, during which time creation of significant environmental emissions and waste containing naturally occurring radionuclides has occurred. Pb-210 and 210 Po are considered natural radionuclides with the highest emission rates from PPs and possess elevated potential radiation exposure risks to humans and the environment. These radionuclides have the highest activity concentration values in fine ash fractions, especially in fractions remaining below 2.5 μm. To determine the activity concentrations of 210 Pb and 210 Po in the PPs' outlet, sampling was conducted from boilers operating on pulverized fuel (PF) technology with novel integrated desulphurization (NID) system and bag filters as well as with electrostatic precipitators (ESPs). The 210 Pb and 210 Po activity concentrations remained around 300 Bq kg -1 for the NID system compared to 60-80 Bq kg -1 in the ESP system. The dominant ash fraction in both systems was PM2.5, constituting over 50% of the fly ash mass collected from the outlet. The authors estimate that the total atmospherically emitted activity for the modernized PPs remains dominantly below 1% of the activity that is inserted via fuel. The implementation of higher efficiency purifications systems has significantly reduced the negative effect of these PPs. Based on annually emitted fly ash and boilers' working hours, the 210 Pb and 210 Po activity released relative to energy production were up to 68.3 kBq GWh el -1 for 210 Pb and 64.6 kBq GWh el -1 for 210 Po. These values are 1 to 2 orders of magnitude lower compared to the situation in the 1980s. These findings represent the first publicly available quantitative results estimating the 210 Po emissions from large oil shale-fired PPs. Copyright © 2016 Elsevier Ltd. All rights reserved.

76 FR 25685 - Pacific Gas and Electric Company; Notice of Application Tendered for Filing With the Commission...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-05

... of Project: Rollins Transmission Line Project. f. Location: The Rollins Transmission Line Project is... Greene, (202) 502-8865 or [email protected] . j. Status: This application is not ready for... mile from NID's Rollins powerhouse switchyard to PG&E's interconnected transmission grid. The project...

Effect of zinc imprinting and replacing inorganic zinc with organic zinc on early performance of broiler chicks.

PubMed

Mwangi, S; Timmons, J; Ao, T; Paul, M; Macalintal, L; Pescatore, A; Cantor, A; Ford, M; Dawson, K A

2017-04-01

The goal of this study was to determine the effects of feeding a zinc (Zn) deficient diet to broiler chicks for 96 h post-hatch followed by feeding diets with different Zn sources and supplemental levels (5 to 21 d) on the growth performance, tissue, and excreta Zn content. At the start of the study, four hundred 20-day-old male broiler chicks were divided into two groups. One group was fed a corn soybean meal based diet containing 25 mg of Zn/kg (imprinting diet, ID). The second group was fed the basal diet supplemented with 40 mg of Zn/kg from Zn oxide (ZnO) (non-imprinting diet, NID). Both groups were fed these diets for 96 h. At d 5, chicks from each group were randomly assigned to the dietary treatments consisting of the basal diet alone or the basal diet supplemented with 8 or 40 mg/kg Zn as ZnO or Zn proteinate. Main effects of post-hatch Zn ID were observed on feed intake and G:F. ID decreased (P < 0.05) feed intake and improved (P < 0.05) the gain to feed ratio (G:F) of 14 and 21 d old chicks compared to G:F of chicks fed NID. Additionally, G:F for 14 and 21 d was improved (P < 0.05) by interaction of Zn source × level. Furthermore, at d 21 chicks fed the ID had a lower (P < 0.05) Zn content in the tibia ash and excreta, and a higher (P < 0.05) Zn content in the pancreas tissue compared to chicks fed NID. These results suggest that Zn imprinting can affect body Zn stores and early performance. © The Author 2016. Published by Oxford University Press on behalf of Poultry Science Association.

7 CFR 1755.501 - Definitions applicable to §§ 1755.501 through 1755.510.

Code of Federal Regulations, 2011 CFR

2011-01-01

... travel use built on or permanently attached to a self-propelled motor vehicle chassis or on a chassis cab... the FCC rules in 47 CFR part 68. NID. Network interface device. Primary station protector. An assembly... and determined that: (1) Final assembly or manufacture of the equipment is completed in the United...

76 FR 35208 - Pacific Gas and Electric Company; Nevada Irrigation District; Notice of Environmental Site Review

Federal Register 2010, 2011, 2012, 2013, 2014

2011-06-16

...; Project No. 2266-102--California] Pacific Gas and Electric Company; Nevada Irrigation District; Notice of... Pacific Gas and Electric Company (PG&E) and Nevada Irrigation District (NID) (applicants) will conduct an... (recommend a 4-wheel drive vehicle), but car pooling to the extent possible is encouraged. We do not...

A Proposal for Kelly CriterionBased Lossy Network Compression

DTIC Science & Technology

2016-03-01

warehousing and data mining techniques for cyber security. New York (NY): Springer; 2007. p. 83–108. 34. Münz G, Li S, Carle G. Traffic anomaly...p. 188–196. 48. Kim NU, Park MW, Park SH, Jung SM, Eom JH, Chung TM. A study on ef- fective hash-based load balancing scheme for parallel nids. In

U.S. EPA, Pesticide Product Label, SECURITY POWERTOX COTTON SPRAY, 12/16/1983

EPA Pesticide Factsheets

2011-04-14

... NI.'D" end only 'or tlloN u_ covered by II .• Certilled Aula lIor ... J,' !)~1 .·.Y"· e'.El" d"~1 ... a~ tt')r VI>;, nc.oj_st.ri\\tiC"I. ~~o. 7GY-J7C'1 cL ...

Bone Mineral Density in Adults With Down Syndrome, Intellectual Disability, and Nondisabled Adults

ERIC Educational Resources Information Center

Geijer, Justin R.; Stanish, Heidi I.; Draheim, Christopher C.; Dengel, Donald R.

2014-01-01

Individuals with intellectual disability (ID) or Down syndrome (DS) may be at greater risk of osteoporosis. The purpose of this study was to compare bone mineral density (BMD) of DS, ID, and non-intellectually disabled (NID) populations. In each group, 33 participants between the ages of 28 and 60 years were compared. BMD was measured with…

The use of seismic tomograms for the identification of internal problems with earthen dams and levees

USDA-ARS?s Scientific Manuscript database

According to the National Inventory of dams (NID, 2009), out of the 84,134 dams in the US, more than 87% (73,423) are earthen dams. The majority of these earthen dams are past or approaching their design life expectancy of 50 years. According to the National committee on Levee Safety (NCLS, 2009),...

Efficient Aho-Corasick String Matching on Emerging Multicore Architectures

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tumeo, Antonino; Villa, Oreste; Secchi, Simone

String matching algorithms are critical to several scientific fields. Beside text processing and databases, emerging applications such as DNA protein sequence analysis, data mining, information security software, antivirus, ma- chine learning, all exploit string matching algorithms [3]. All these applica- tions usually process large quantity of textual data, require high performance and/or predictable execution times. Among all the string matching algorithms, one of the most studied, especially for text processing and security applica- tions, is the Aho-Corasick algorithm. 1 2 Book title goes here Aho-Corasick is an exact, multi-pattern string matching algorithm which performs the search in a time linearlymore » proportional to the length of the input text independently from pattern set size. However, depending on the imple- mentation, when the number of patterns increase, the memory occupation may raise drastically. In turn, this can lead to significant variability in the performance, due to the memory access times and the caching effects. This is a significant concern for many mission critical applications and modern high performance architectures. For example, security applications such as Network Intrusion Detection Systems (NIDS), must be able to scan network traffic against very large dictionaries in real time. Modern Ethernet links reach up to 10 Gbps, and malicious threats are already well over 1 million, and expo- nentially growing [28]. When performing the search, a NIDS should not slow down the network, or let network packets pass unchecked. Nevertheless, on the current state-of-the-art cache based processors, there may be a large per- formance variability when dealing with big dictionaries and inputs that have different frequencies of matching patterns. In particular, when few patterns are matched and they are all in the cache, the procedure is fast. Instead, when they are not in the cache, often because many patterns are matched and the caches are continuously thrashed, they should be retrieved from the system memory and the procedure is slowed down by the increased latency. Efficient implementations of string matching algorithms have been the fo- cus of several works, targeting Field Programmable Gate Arrays [4, 25, 15, 5], highly multi-threaded solutions like the Cray XMT [34], multicore proces- sors [19] or heterogeneous processors like the Cell Broadband Engine [35, 22]. Recently, several researchers have also started to investigate the use Graphic Processing Units (GPUs) for string matching algorithms in security applica- tions [20, 10, 32, 33]. Most of these approaches mainly focus on reaching high peak performance, or try to optimize the memory occupation, rather than looking at performance stability. However, hardware solutions supports only small dictionary sizes due to lack of memory and are difficult to customize, while platforms such as the Cell/B.E. are very complex to program.« less

Massive outbreak of poliomyelitis caused by type-3 wild poliovirus in Angola in 1999.

PubMed Central

Valente, F.; Otten, M.; Balbina, F.; Van de Weerdt, R.; Chezzi, C.; Eriki, P.; Van-Dúnnen, J.; Bele, J. M.

2000-01-01

The largest outbreak of poliomyelitis ever recorded in Africa (1093 cases) occurred from 1 March to 28 May 1999 in Luanda, Angola, and in surrounding areas. The outbreak was caused primarily by a type-3 wild poliovirus, although type-1 wild poliovirus was circulating in the outbreak area at the same time. Infected individuals ranged in age from 2 months to 22 years; 788 individuals (72%) were younger than 3 years. Of the 590 individuals whose vaccination status was known, 23% had received no vaccine and 54% had received fewer than three doses of oral poliovirus vaccine (OPV). The major factors that contributed to this outbreak were as follows: massive displacement of unvaccinated persons to urban settings; low routine OPV coverage; inaccessible populations during the previous three national immunization days (NIDs); and inadequate sanitation. This outbreak indicates the urgent need to improve accessibility to all children during NIDs and the dramatic impact that war can have by displacing persons and impeding access to routine immunizations. The period immediately after an outbreak provides an enhanced opportunity to eradicate poliomyelitis. If continuous access in all districts for acute flaccid paralysis surveillance and supplemental immunizations cannot be assured, the current war in Angola may threaten global poliomyelitis eradication. PMID:10812730

A novel retinoic acid, catechin hydrate and mustard oil-based emulsion for enhanced cytokine and antibody responses against multiple strains of HIV-1 following mucosal and systemic vaccinations

PubMed Central

Yu, Mingke; Vajdy, Michael

2011-01-01

Non-replicating protein- or DNA-based antigens generally require immune-enhancing adjuvants and delivery systems. It has been particularly difficult to raise antibodies against gp120 of HIV-1, which constitutes an important approach in HIV vaccine design. While almost all effort in adjuvant research has focused on mimicking the pathogens and the danger signals they engender in the host, relatively little effort has been spent on nutritive approaches. In this study, a new nutritive immune-enhancing delivery system (NIDS) composed of vitamin A, a polyphenol-flavonoid catechin hydrate, and mustard oil was tested for its adjuvant effect in immune responses against the gp120 protein of HIV-1CN54. Following a combination of two mucosal and two systemic vaccinations of mice, we found significant enhancement of both local and systemic antibodies as well as cytokine responses. These data have important implications for vaccine and adjuvant design against HIV-1 and other pathogens. PMID:21272602

Investigating the relationship between self-rated health and social capital in South Africa: a multilevel panel data analysis.

PubMed

Lau, Yan Kwan; Ataguba, John E

2015-03-19

The relationship between social capital and self-rated health has been documented in many developed compared to developing countries. Because social capital and health play important roles in development, it may be valuable to study their relationship in the context of a developing country with poorer health status. Further, the role of social capital research for health policy has not received much attention. This paper therefore examines the relationship between social capital and health in South Africa, a country with the history of colonialism and apartheid that has contributed to the social disintegration and destruction of social capital. This study uses data from the National Income Dynamics Study (NIDS), the first nationally representative panel study in South Africa. Two waves of the NIDS were used in this paper--Wave 1 (2008) and Wave 2 (2010). Self-rated health, social capital (individual- and contextual-level), and other covariates related to the social determinants of health (SDH) were obtained from the NIDS. Individual-level social capital included group participation, personalised trust and generalised trust while contextual-level or neighbourhood-level social capital was obtained by aggregating from the individual-level and household-level social capital variables to the neighbourhood. Mixed effects models were fitted to predict self-rated health in Wave 2, using lagged covariates (from Wave 1). Individual personalised trust, individual community service group membership and neighbourhood personalised trust were beneficial to self-rated health. Reciprocity, associational activity and other types of group memberships were not found to be significantly associated with self-rated health in South Africa. Results indicate that both individual- and contextual-level social capital are associated with self-rated health. Policy makers may want to consider policies that impact socioeconomic conditions as well as social capital. Some of these policies are linked to the SDH. We contend that the significant social capital including community service membership can be encouraged through policy in a way that is in line with the values of the people. This is likely to impact on health and quality of life generally and lead to a reduction in the burden of disease in South Africa considering the historic context of the country.

Community structure and PAH ring-hydroxylating dioxygenase genes of a marine pyrene-degrading microbial consortium.

PubMed

Gallego, Sara; Vila, Joaquim; Tauler, Margalida; Nieto, José María; Breugelmans, Philip; Springael, Dirk; Grifoll, Magdalena

2014-07-01

Marine microbial consortium UBF, enriched from a beach polluted by the Prestige oil spill and highly efficient in degrading this heavy fuel, was subcultured in pyrene minimal medium. The pyrene-degrading subpopulation (UBF-Py) mineralized 31 % of pyrene without accumulation of partially oxidized intermediates indicating the cooperation of different microbial components in substrate mineralization. The microbial community composition was characterized by culture dependent and PCR based methods (PCR-DGGE and clone libraries). Molecular analyses showed a highly stable community composed by Alphaproteobacteria (84 %, Breoghania, Thalassospira, Paracoccus, and Martelella) and Actinobacteria (16 %, Gordonia). The members of Thalasosspira and Gordonia were not recovered as pure cultures, but five additional strains, not detected in the molecular analysis, that classified within the genera Novosphingobium, Sphingopyxis, Aurantimonas (Alphaproteobacteria), Alcanivorax (Gammaproteobacteria) and Micrococcus (Actinobacteria), were isolated. None of the isolates degraded pyrene or other PAHs in pure culture. PCR amplification of Gram-positive and Gram-negative dioxygenase genes did not produce results with any of the cultured strains. However, sequences related to the NidA3 pyrene dioxygenase present in mycobacterial strains were detected in UBF-Py consortium, suggesting the representative of Gordonia as the key pyrene degrader, which is consistent with a preeminent role of actinobacteria in pyrene removal in coastal environments affected by marine oil spills.

Fog Evolution in the Visible and Infrared Spectral Regions and Its Meaning in Optical Modeling

DTIC Science & Technology

1979-12-01

8217 ilatiton flr -KmniCs Stret ’i-bite’ I’t, tnsmitttat’e ~Nit (il’.:’’ l )Nt-.5t;7.,*JtIl\\ 19175. .1. 111&1tiIo. .. , I nid It. .ttaigt’loe "BIallisti WiX ~ndI...8217’Temperature Nvasuroments in thet Stratosphere from Balloon- Borne Instrument Platforms , 1968-1975," E(’(M.5808, Decembiler 1976. 45. Mlonahan, II.11., ’’An

ISDAC Microphysics

DOE Data Explorer

McFarquhar, Greg

2011-07-25

Best estimate of cloud microphysical parameters derived using data collected by the cloud microphysical probes installed on the National Research Council (NRC) of Canada Convair-580 during ISDAC. These files contain phase, liquid and ice crystal size distributions (Nw(D) and Ni(D) respectively), liquid water content (LWC), ice water content (IWC), extinction of liquid drops (bw), extinction of ice crystals (bi), effective radius of water drops (rew) and of ice crystals (rei) and median mass diameter of liquid drops (Dmml) and of ice crystals (Dmmi) at 30 second resolution.

Why Does Mptcp Have To Make Things So Complicated : Cross Path Nids Evasion And Countermeasures

DTIC Science & Technology

2016-09-01

previously only establish communication channels over single network paths to communicate over multiple network paths. MPTCP is an enhancement toTCP that...the attacker would fail to create a Command and Control (C2) channel unless the attacker had created a new mapping to the target on the splicing...machine. This would allow the attacker to conduct C2 over a spliced channel . This may even make the attacker’s C2 more evasive. In fact, the effect

Evaluation of the testicular toxicity of prenatal exposure to bisphenol A based on microarray analysis combined with MeSH annotation.

PubMed

Tainaka, Hitoshi; Takahashi, Hikari; Umezawa, Masakazu; Tanaka, Hiromitsu; Nishimune, Yoshitake; Oshio, Shigeru; Takeda, Ken

2012-01-01

Bisphenol A (BPA) is known to be an endocrine disruptor that affects the development of reproductive system. The aim of the present study was to investigate a group of testicular genes dysregulated by prenatal exposure to BPA. Pregnant ICR mice were treated with BPA by subcutaneous administration on days 7 and 14 of pregnancy. Tissue and blood samples were collected from 6-week-old male offspring. Testes were subjected to gene expression analysis using a testis-specific microarray (Testis2), consisting of 2,482 mouse cDNA clones annotated with Medical Subject Headings (MeSH) terms indicative of testicular components and functions. To interpret the microarray data, we used the MeSH terms significantly associated with the altered genes. As a result, MeSH terms related to androgens and Sertoli cells were extracted in BPA-treated groups. Among the genes related to Sertoli cells, downregulation of Msi1h, Ncoa1, Nid1, Hspb2, and Gata6 were detected in the testis of mice treated with BPA (twice administered 50 mg/kg). The MeSH terms associated with this group of genes may provide useful means to interpret the testicular toxicity of BPA. This article concludes that prenatal BPA exposure downregulates expression of genes associated with Sertoli cell function and affects the reproductive function of male offspring. Additionally, a method using MeSH to extract a group of genes was useful for predicting the testicular and reproductive toxicity of prenatal BPA exposure.

[RELATIONSHIP BETWEEN THE PREVALENCE OF CHRONIC NONINFECTIOUS DISEASES AND ELECTROPHYSICAL STATE OF THE ENVIRONMENT].

PubMed

Rakhmanin, Yu A; Stekhin, A A; Yakovleva, G V; Karasev, A K; Marasanov, A V; Iksanova, T I; Ryabikov, V V

2015-01-01

In the paper there is evaluated the relationship of features of electronic state of the environment with a level of chronic, noninfectious diseases (CNID) in the regions of Russia, obtained on the basis of the monitoring measurements of the intensity of natural background electronic Bose condensate (BEBC) of natural ecosystems in a number of Russian regions and seas of the Arctic Ocean. The assessment of BEBC was implemented on results of measurements of redox state of distilled water being in the contact with natural water. The equilibrium redox state of distilled water, determined by the influx of electrons (quantum reduction) outside, is proportional to the intensity of BEBC. The obtained data attest to an increase in the intensity of the background of EBC in Siberia regions and, especially, within the limits ofwaters of Lake Baikal (the redox potential of the surface water in the lake ~ -70mV). Also there is observed a strong dependence of the background EBC in the latitudinal direction. Low levels of background EBC were noted in the Arkhangelsk region and the north-eastern Chukotka. Functioning of international systems of plasma sounding of ionosphere (such systems as HAARP) were established to have a detrimental effect on the background EBC in these regions. According to the results of measurements of the relative values of intensities of natural background of Bose condensate of electrons there was constructed the dependence reflecting the relationship of the prevalence of noninfectious diseases in the regions of Russia with the redox state of distilled water which can be characterized as a significant (regression coefficient R2 = 0.78). The relationship between noninfectious diseases (NID, %) with the intensity of the background of EBC (Ib rel. units) is estimated by the equation: NID [%] = 0.24Eh [mV]-25, where Eh ~ I/Ib. Numerical evaluations show that an increase in the biosphere redox potential of water by 90mV leads to an increase of the primary incidence by 20% (relatively to the average values for Russia). Analysis of results attests to the relationship of CNID with the electrophysical state of the environment that allows from different positions to arrive to true causes of their emergence, associated with changes in the electrophysical conditions of habitation and human activities that lead to the nascency of cellular metabolic disturbances.

Compensation of significant parametric uncertainties using sliding mode online learning

NASA Astrophysics Data System (ADS)

Schnetter, Philipp; Kruger, Thomas

An augmented nonlinear inverse dynamics (NID) flight control strategy using sliding mode online learning for a small unmanned aircraft system (UAS) is presented. Because parameter identification for this class of aircraft often is not valid throughout the complete flight envelope, aerodynamic parameters used for model based control strategies may show significant deviations. For the concept of feedback linearization this leads to inversion errors that in combination with the distinctive susceptibility of small UAS towards atmospheric turbulence pose a demanding control task for these systems. In this work an adaptive flight control strategy using feedforward neural networks for counteracting such nonlinear effects is augmented with the concept of sliding mode control (SMC). SMC-learning is derived from variable structure theory. It considers a neural network and its training as a control problem. It is shown that by the dynamic calculation of the learning rates, stability can be guaranteed and thus increase the robustness against external disturbances and system failures. With the resulting higher speed of convergence a wide range of simultaneously occurring disturbances can be compensated. The SMC-based flight controller is tested and compared to the standard gradient descent (GD) backpropagation algorithm under the influence of significant model uncertainties and system failures.

Israel’s Interests and Options in Syria

DTIC Science & Technology

2016-01-01

israel-syria-druze-golan-heights-assad-rebels-civil-war.html ———, “Israel Fears Return of Persian Empire,” Al-Monitor, September 21, 2015b. As of...December 14, 2015: http://www.al-monitor.com/pulse/originals/2015/09/ israel-fear- persian -empire-iran-shiite-hezbollah-axis-nuke.html ———, “Russia, Israeli...December 14, 2015: http://www.israeltoday.co.il/NewsItem/tabid/178/nid/23796/Default.aspx Peled, Daniella, “ISIS in Jordan: King Abdullah’s Battle for the

Combined use of Kappa Free Light Chain Index and Isoelectrofocusing of Cerebro-Spinal Fluid in Diagnosing Multiple Sclerosis: Performances and Costs.

PubMed

Crespi, Ilaria; Sulas, Maria Giovanna; Mora, Riccardo; Naldi, Paola; Vecchio, Domizia; Comi, Cristoforo; Cantello, Roberto; Bellomo, Giorgio

2017-03-01

Isoelectrofocusing (IEF) to detect oligoclonal bands (OBCs) in cerebrospinal fluid (CSF) is the gold standard approach for evaluating intrathecal immunoglobulin synthesis in multiple sclerosis (MS) but the kappa free light chain index (KFLCi) is emerging as an alternative marker, and the combined/sequential uses of IEF and KFLCi have never been challenged. CSF and serum albumin, IgG, kFLC and lFLC were measured by nephelometry; albumin, IgG and kFLC quotients as well as Link and kFLC indexes were calculated; OCBs were evaluated by immunofixation. A total of 150 consecutive patients: 48 with MS, 32 with other neurological inflammatory diseases (NID), 62 with neurological non-inflammatory diseases (NNID), and 8 without any detectable neurological disease (NND) were investigated. Both IEF and KFLCi showed a similar accuracy as diagnostic tests for multiple sclerosis. The high sensitivity and specificity associated with the lower cost of KFLCi suggested to use this test first, followed by IEF as a confirmative procedure. The sequential use of IEF and KFLCi showed high diagnostic efficiency with cost reduction of 43 and 21%, if compared to the contemporary use of both tests, or the unique use of IEF in all patients. The "sequential testing" using KFLCi followed by IEF in MS represents an optimal procedure with accurate performance and lower costs.

Rhizoremediation of phenanthrene and pyrene contaminated soil using wheat.

PubMed

Shahsavari, Esmaeil; Adetutu, Eric M; Taha, Mohamed; Ball, Andrew S

2015-05-15

Rhizoremediation, the use of the plant rhizosphere and associated microorganisms represents a promising method for the clean up of soils contaminated with polycyclic aromatic hydrocarbons (PAHs) including phenanthrene and pyrene, two model PAHs. Although numerous studies have been published reporting the degradation of phenanthrene and pyrene, very few evaluate the microbial basis of the rhizoremediation process through the application of molecular tools. The aim of this study was to investigate the effect of wheat on the degradation of two model PAHs (alone or in combination) and also on soil bacterial, fungal and nidA gene (i.e. a key gene in the degradation of pyrene) communities. The addition of wheat plants led to a significant enhancement in the degradation of both phenanthrene and pyrene. In pyrene-contaminated soils, the degradation rate increased from 15% (65 mg/kg) and 18% (90 mg/kg) in unplanted soils to 65% (280 mg/kg) and 70% (350 mg/kg) in planted treatments while phenanthrene reduction was enhanced from 97% (394 mg/kg) and 87% (392 mg/kg) for unplanted soils to 100% (406 mg/kg) and 98% (441 mg/kg) in the presence of wheat. PCR-DGGE results showed that the plant root let to some changes in the bacterial and fungal communities; these variations did not reflect any change in hydrocarbon-degrading communities. However, plate counting, traditional MPN and MPN-qPCR of nidA gene revealed that the wheat rhizosphere led to an increase in the total microbial abundance including PAH degrading organisms and these increased activities resulted in enhanced degradation of phenanthrene and pyrene. This clearer insight into the mechanisms underpinning PAH degradation will enable better application of this environmentally friendly technique. Copyright © 2015 Elsevier Ltd. All rights reserved.

Effect of teriparatide treatment on endothelial function, glucose metabolism and inflammation markers in patients with postmenopausal osteoporosis.

PubMed

Celer, Ozgen; Akalın, Aysen; Oztunali, Cigdem

2016-10-01

Teriparatide, an anabolic agent used in the treatment of postmenopausal osteoporosis, can induce effects similar to primary hyperparathyroidism. Our objective was to evaluate the effects of teriparatide on endothelial functions, glucose metabolism and inflammation markers in patients diagnosed with postmenopausal osteoporosis. This was a single-centre, single-arm, 6-month prospective study. Twenty-three postmenopausal women over 65 years old with a lumbar spine or femoral neck T-score of -4·0 or lower and having at least two compression fractures in thoracic or lumbar spine were studied. Low-dose intermittent teriparatide (20 μg/day) was supplemented with calcium carbonate (1000 mg elemental calcium) and 880 IU cholecalciferol for 6 months. The biochemical parameters for glucose metabolism, inflammation and atherosclerosis were determined. For the assessment of vascular endothelial function, carotid intima-media thickness (CIMT), brachial artery intima-media thickness (BIMT), per cent change in flow-mediated dilation (FMD%) and nitroglycerine-induced dilations (NID%) were measured on ultrasonography. The fasting plasma glucose, homoeostatic model assessment of insulin resistance, fibrinogen, homocysteine and high-density lipoprotein cholesterol increased significantly with teriparatide treatment (P < 0·05 for all). Baseline CIMT and BIMT did not change significantly with 6 months of teriparatide treatment (P > 0·05); however, FMD% and NID% showed significant decrease after treatment (P < 0·01 for both). Intermittent teriparatide treatment may adversely affect some parameters of glucose metabolism, inflammation and endothelial function. On the basis of our findings, further large-scale and controlled studies are needed to clarify the exact effect of teriparatide treatment on glucose metabolism, inflammation and endothelial function. © 2016 John Wiley & Sons Ltd.

Crystal structures of NiSO4·9H2O and NiSO4·8H2O: magnetic properties, stability with respect to morenosite (NiSO4·7H2O), the solid-solution series (Mg x Ni1-x )SO4·9H2O

NASA Astrophysics Data System (ADS)

Fortes, A. D.; Knight, K. S.; Gibbs, A. S.; Wood, I. G.

2018-02-01

Since being discovered initially in mixed-cation systems, a method of forming end-member NiSO4·9H2O and NiSO4·8H2O has been found. We have obtained powder diffraction data from protonated analogues (with X-rays) and deuterated analogues (using neutrons) of these compounds over a range of temperatures, allowing us to determine their crystal structures—including all H-atoms—and to characterise the transitions on warming from 220 to 278 K; glass → 9-hydrate → 8-hydrate + ice → 7-hydrate + ice → partial melt (7-hydrate + liquid). NiSO4·8D2O is triclinic, space-group P\\bar {1} , Z = 2, with unit cell parameters at 150 K, a = 6.12463(8) Å, b = 6.8401(1) Å, c = 12.5339(2) Å, α = 92.846(1)°, β = 97.822(1)°, γ = 96.627(1)° and V = 515.58(1) Å3. The structure consists of two symmetry-inequivalent Ni(D2O)6 octahedra on sites of \\bar {1} symmetry. These are directly joined by a water-water H-bond to form chains of octahedra parallel with the c-axis at x = 0. Two interstitial water molecules serve both to bridge the Ni(D2O)6 octahedral chains in the b-c plane and also to connect with the SO4 2- tetrahedral oxyanion. These tetrahedra are linked by the two interstitial water molecules in a reticular motif to form sheets perpendicular to c. NiSO4·9D2O is monoclinic, space-group P21/c, Z = 4, with unit-cell parameters at 150 K, a = 6.69739(6) Å, b = 11.8628(1) Å, c = 14.5667(1) Å, β = 94.9739(8)° and V = 1152.96(1) Å3. The structure is isotypic with the Mg analogue described elsewhere (Fortes et al., Acta Cryst B 73:47‒64, 2017b). It shares the motif of H-bonded octahedral chains with NiSO4·8D2O, although in the enneahydrate these run parallel with the b-axis at x = 0. Three interstitial water molecules bridge the Ni(D2O)6 octahedra to the SO4 2- tetrahedral oxyanion. The tetrahedra sit at x ≈ 0.5 and are linked by two of the three interstitial water molecules in a pentagonal motif to form ribbons parallel with b. A solid-solution series exists between Mg and Ni enneahydrate end-members where we observe preferential partitioning of Ni2+ into the octahedral sites on the 2c Wyckoff positions rather than the 2a sites. The solution is slightly non-ideal, as indicated by the small positive excess volume of mixing. Measurements of the DC magnetisation of quenched NiSO4 solutions reveal anomalies in the molar susceptibility on warming through the region from 221 to 225 K, probably due to devitrification of the (assumed) glassy specimen into a mixture of NiSO4·9H2O + ice Ih. Further temperature-dependent measurements on repeated warming and cooling provide no evidence of magnetic ordering and indicate a weak ferromagnetic coupling between neighbouring Ni2+ ions, likely via super-exchange through the H-bond between neighbouring Ni(H2O)6 octahedra.

Polycyclic aromatic hydrocarbons (PAHs) biodegradation potential and diversity of microbial consortia enriched from tsunami sediments in Miyagi, Japan.

PubMed

Bacosa, Hernando Pactao; Inoue, Chihiro

2015-01-01

The Great East Japan Earthquake caused tsunamis and resulted in widespread damage to human life and infrastructure. The disaster also resulted in contamination of the environment by chemicals such as polycyclic aromatic hydrocarbons (PAHs). This study was conducted to investigate the degradation potential and describe the PAH-degrading microbial communities from tsunami sediments in Miyagi, Japan. PAH-degrading bacteria were cultured by enrichment using PAH mixture or pyrene alone as carbon and energy sources. Among the ten consortia tested for PAH mixture, seven completely degraded fluorene and more than 95% of phenanthrene in 10 days, while only four consortia partially degraded pyrene. Six consortia partially degraded pyrene as a single substrate. Polymerase chain reaction-denaturing gradient gel electrophoresis (PCR-DGGE) revealed that each sample was dominated by unique microbial populations, regardless of sampling location. The consortia were dominated by known PAHs degraders including Sphingomonas, Pseudomonas, and Sphingobium; and previously unknown degraders such as Dokdonella and Luteimonas. A potentially novel and PAH-degrading Dokdonella was detected for the first time. PAH-ring hydroxylating dioxygenase (PAH-RHDα) gene was shown to be more effective than nidA in estimating pyrene-degrading bacteria in the enriched consortia. The consortia obtained in this study are potential candidates for remediation of PAHs contaminated soils. Copyright © 2014 Elsevier B.V. All rights reserved.

Modulation of microbial consortia enriched from different polluted environments during petroleum biodegradation.

PubMed

Omrani, Rahma; Spini, Giulia; Puglisi, Edoardo; Saidane, Dalila

2018-04-01

Environmental microbial communities are key players in the bioremediation of hydrocarbon pollutants. Here we assessed changes in bacterial abundance and diversity during the degradation of Tunisian Zarzatine oil by four indigenous bacterial consortia enriched from a petroleum station soil, a refinery reservoir soil, a harbor sediment and seawater. The four consortia were found to efficiently degrade up to 92.0% of total petroleum hydrocarbons after 2 months of incubation. Illumina 16S rRNA gene sequencing revealed that the consortia enriched from soil and sediments were dominated by species belonging to Pseudomonas and Acinetobacter genera, while in the seawater-derived consortia Dietzia, Fusobacterium and Mycoplana emerged as dominant genera. We identified a number of species whose relative abundances bloomed from small to high percentages: Dietzia daqingensis in the seawater microcosms, and three OTUs classified as Acinetobacter venetianus in all two soils and sediment derived microcosms. Functional analyses on degrading genes were conducted by comparing PCR results of the degrading genes alkB, ndoB, cat23, xylA and nidA1 with inferences obtained by PICRUSt analysis of 16S amplicon data: the two data sets were partly in agreement and suggest a relationship between the catabolic genes detected and the rate of biodegradation obtained. The work provides detailed insights about the modulation of bacterial communities involved in petroleum biodegradation and can provide useful information for in situ bioremediation of oil-related pollution.

Pulsed-neutron imaging by a high-speed camera and center-of-gravity processing

NASA Astrophysics Data System (ADS)

Mochiki, K.; Uragaki, T.; Koide, J.; Kushima, Y.; Kawarabayashi, J.; Taketani, A.; Otake, Y.; Matsumoto, Y.; Su, Y.; Hiroi, K.; Shinohara, T.; Kai, T.

2018-01-01

Pulsed-neutron imaging is attractive technique in the research fields of energy-resolved neutron radiography and RANS (RIKEN) and RADEN (J-PARC/JAEA) are small and large accelerator-driven pulsed-neutron facilities for its imaging, respectively. To overcome the insuficient spatial resolution of the conunting type imaging detectors like μ NID, nGEM and pixelated detectors, camera detectors combined with a neutron color image intensifier were investigated. At RANS center-of-gravity technique was applied to spots image obtained by a CCD camera and the technique was confirmed to be effective for improving spatial resolution. At RADEN a high-frame-rate CMOS camera was used and super resolution technique was applied and it was recognized that the spatial resolution was futhermore improved.

Preliminary Inventory of the Retired Records of the 1st United States Army Infantry Division during the Vietnam War, 2 October 1965-14 April 1970. Sanitized Version.

DTIC Science & Technology

1982-05-01

con Oft uh 6 to the appdsb feual Rec"It Comer for RECORDS TRANSMITTAL AND RECEIPT apm pro to shipaat of f Spse arcns aon rese. PAMIf A. TO 4i5 ASd5 * pv... gmo -M IN nm nd 10mi AV No*5 m General Orders; General Correspondence; Daily Staff Journals; Tactical Operatiod Center (TOC) Logs; Cmand Reports...AGENiCYwo m a gewn.uirm DIPSL " 1n 2,I (w l6_t 4,11A 4s. 41) pollo~ 01)S 10~e 1~e (1) (A)A. IndiOs Cap Ill StA SAC(G3O4NID: Th.&. record. were pros edfor

HABP2 p.G534E variant in patients with family history of thyroid and breast cancer

PubMed Central

Pinheiro, Maisa; Drigo, Sandra Aparecida; Tonhosolo, Renata; Andrade, Sonia C.S.; Marchi, Fabio Albuquerque; Jurisica, Igor; Kowalski, Luiz Paulo; Achatz, Maria Isabel; Rogatto, Silvia Regina

2017-01-01

Familial Papillary Thyroid Carcinoma (PTC) has been described as a hereditary predisposition cancer syndrome associated with mutations in candidate genes including HABP2. Two of 20 probands from families with history of PTC and breast carcinoma (BC) were evaluated by whole exome sequencing (WES) revealing HABP2 p.G534E. Sanger sequencing was used to confirm the involvement of this variant in three families (F1: 7 relatives; F2: 3 and F3: 3). The proband and his sister (with no malignant tumor so far) from F1 were homozygous for the variant whereas one relative with PTC from F2 was negative for the variant. Although the proband of the F3 with PTC was HABP2 wild type, three relatives presented the variant. Five of 170 healthy Brazilian individuals with no family history of BC or PTC and three of 50 sporadic PTC presented the p.G534E. These findings suggested no association of this variant with our familial PTC cases. Genes potentially associated with deregulation of the extracellular matrix organization pathway (CTSB, TNXB, COL4A3, COL16A1, COL24A1, COL5A2, NID1, LOXL2, MMP11, TRIM24 and MUSK) and DNA repair function (NBN and MSH2) were detected by WES, suggesting that other cancer-associated genes have pathogenic effects in the risk of familial PTC development. PMID:28402931

Microstructure of hydrogenated Mg2Ni studied by SANS

NASA Astrophysics Data System (ADS)

Mori, K.; Sugiyama, M.; Iwase, K.; Kawabe, S.; Onodera, Y.; Itoh, K.; Otomo, T.; Fukunaga, T.

2010-10-01

X-ray powder diffraction (XRD) and small-angle neutron scattering (SANS) experiments were carried out for the hydrogenated and duterated Mg2Ni, respectively. According to the results of XRD experiments, both of them coexisted with unhydrogenated (or undeuterated) Mg2Ni in the hydrogen absorbing cycle. Furthermore, in the SANS experiments, a slope of SANS curve, I(Q), was roughly evaluated by using the following power law: I(Q) propto Q-m, where Q is the magnitude of the scattering vector, and m can be equated with a fractal dimensionality, DS (= 6 - m). In conclusion, the hydrogenated and duterated Mg2Ni showed DS~ 3 and ~ 2, respectively. The significant difference between DS's can be understood by considering the scattering length densities, ρ, of Mg2Ni, Mg2NiH4, and Mg2NiD4.

Post-prior equivalence for transfer reactions with complex potentials

NASA Astrophysics Data System (ADS)

Lei, Jin; Moro, Antonio M.

2018-01-01

In this paper, we address the problem of the post-prior equivalence in the calculation of inclusive breakup and transfer cross sections. For that, we employ the model proposed by Ichimura et al. [Phys. Rev. C 32, 431 (1985), 10.1103/PhysRevC.32.431], conveniently generalized to include the part of the cross section corresponding the transfer to bound states. We pay particular attention to the case in which the unobserved particle is left in a bound state of the residual nucleus, in which case the theory prescribes the use of a complex potential, responsible for the spreading width of the populated single-particle states. We see that the introduction of this complex potential gives rise to an additional term in the prior cross-section formula, not present in the usual case of real binding potentials. The equivalence is numerically tested for the 58Ni(d ,p X ) reaction.

Defining dignity and its place in human rights.

PubMed

Michael, Lucy

2014-01-01

The concept of dignity is widely used in society, particularly in reference to human rights law and bioethics. Several conceptions of dignity are identified, falling broadly within two categories: full inherent dignity (FID) and non-inherent dignity (NID). FID is a quality belonging equally to every being with full moral status, including all members of the human natural kind; it is permanent, unconditional, indivisible and inviolable. Those beings with FID ought to be treated deferentially by others by virtue of their belonging to a noble caste. FID grounds fundamental human rights, such as the rights to freedom and equality. The concept of dignity forms a network of interconnected ideas related to worth and value particularly within legal and ethical discourse; it is a rich and meaningful concept, irreducible to one or two quasi-legal principles. Fundamentally, dignity matters because it forms the foundation of civilized society; without it, serious abuse of people is more likely to occur.

Mercury-Bridged Cobaltacarborane Complexes Containing B-Hg-B Three-Center Bonds. Synthesis and Structure of mu, mu’-((n5-C5R5)Co(CH3)2C2B3H4)Hg, mu-(n(5)-C5R5)Co(CH3)2C2B3H4)HgCl, (R=H, CH3) and Related Compounds.

DTIC Science & Technology

1980-11-01

MERCURY-BRIDGED COBALTACARBORANE COMPLEXES CONTAINING B-HG-B TH--ETC(U) NOV 80 D C FINSTER . R N GRIMES N0 0 0 1 4-75-0305 UNCLASSXFIED TR󈧨 NL ILn...C5R5) Co 3)2C2B3 4 2 5 .- -C5R5 )Co(CH3)2C2B3H4 ]HgCl, (R=H, CH3 ) and Related Compounds, David C./ Finster -- Russell N./Grimes ( Department of Chemistry...Compounds 1 \\David C. Finster And Russell N. Grimes* Abstract. Reactions of the nid~p-cobaltacarborane anions 01CR )(C 3 )C BH and [n (H 1oC ihH~5n 5

Effects of the breed, sex and age on cellular content and growth factor release from equine pure-platelet rich plasma and pure-platelet rich gel.

PubMed

Giraldo, Carlos E; López, Catalina; Álvarez, María E; Samudio, Ismael J; Prades, Marta; Carmona, Jorge U

2013-02-12

There is no information on the effects of the breed, gender and age on the cellular content and growth factor (GF) release from equine pure-platelet rich plasma (P-PRP) and pure-platelet rich gel (P-PRG). The objectives of this study were: 1) to compare the cellular composition of P-PRP with whole blood and platelet poor plasma (PPP); 2) to compare the concentration of transforming GF beta 1 (TGF-β1) and platelet derived GF isoform BB (PDGF-BB) between P-PRP treated with non-ionic detergent (P-PRP+NID), P-PRG (activated with calcium gluconate -CG-), PPP+NID, PPP gel (PPG), and plasma and; 3) to evaluate and to correlate the effect of the breed, gender and age on the cellular and GF concentration for each blood component. Forty adult horses, 20 Argentinean Creole Horses (ACH) and, 20 Colombian Creole Horses (CCH) were included. Data were analyzed by parametric (i.e.: t-test, one way ANOVA) and non parametric (Kruskal-Wallis test, Wilcoxon test) tests. Correlation analysis was also performed by using the Spearman and Pearson tests. A p ≤ 0.05 was set as significant for all tests. All the blood components were compared for platelet (PLT), leukocyte (WBC), TGF-β1 and PDGF-BB concentrations. The effect of the breed, gender and age on these variables was analyzed. A P ≤ 0.05 was accepted as significant for all the tests. PLT counts were 1.8 and 0.6 times higher in P-PRP than in whole blood and PPP, respectively; WBC counts were 0.5 and 0.1 times lower in P-PRP, in comparison with whole blood and PPP, respectively. TGF-β1 and PDGF-BB concentrations were 2.3 and 262 times higher, respectively, in P-PRG than in plasma, and 0.59 and 0.48 times higher, respectively, in P-PRG than in PPG. P-PRG derived from CCH females or young horses presented significantly (P < 0.001) higher PDGF-BB concentrations than P-PRG derived from ACH males or older horses. Our results indicated that P-PRP obtained by a manual method was affected by intrinsic factors such as the breed, gender and age. Equine practitioners should be aware that cellular and GF release from P-PRP/P-PRG could change according with the intrinsic variables associated with a patient in particular.

Genome-wide association studies in East Asians identify new loci for waist-hip ratio and waist circumference

PubMed Central

Wen, Wanqing; Kato, Norihiro; Hwang, Joo-Yeon; Guo, Xingyi; Tabara, Yasuharu; Li, Huaixing; Dorajoo, Rajkumar; Yang, Xiaobo; Tsai, Fuu-Jen; Li, Shengxu; Wu, Ying; Wu, Tangchun; Kim, Soriul; Guo, Xiuqing; Liang, Jun; Shungin, Dmitry; Adair, Linda S.; Akiyama, Koichi; Allison, Matthew; Cai, Qiuyin; Chang, Li-Ching; Chen, Chien-Hsiun; Chen, Yuan-Tsong; Cho, Yoon Shin; Choi, Bo Youl; Gao, Yutang; Go, Min Jin; Gu, Dongfeng; Han, Bok-Ghee; He, Meian; Hixson, James E.; Hu, Yanling; Huang, Tao; Isono, Masato; Jung, Keum Ji; Kang, Daehee; Kim, Young Jin; Kita, Yoshikuni; Lee, Juyoung; Lee, Nanette R.; Lee, Jeannette; Wang, Yiqin; Liu, Jian-Jun; Long, Jirong; Moon, Sanghoon; Nakamura, Yasuyuki; Nakatochi, Masahiro; Ohnaka, Keizo; Rao, Dabeeru; Shi, Jiajun; Sull, Jae Woong; Tan, Aihua; Ueshima, Hirotsugu; Wu, Chen; Xiang, Yong-Bing; Yamamoto, Ken; Yao, Jie; Ye, Xingwang; Yokota, Mitsuhiro; Zhang, Xiaomin; Zheng, Yan; Qi, Lu; Rotter, Jerome I.; Jee, Sun Ha; Lin, Dongxin; Mohlke, Karen L.; He, Jiang; Mo, Zengnan; Wu, Jer-Yuarn; Tai, E. Shyong; Lin, Xu; Miki, Tetsuro; Kim, Bong-Jo; Takeuchi, Fumihiko; Zheng, Wei; Shu, Xiao-Ou

2016-01-01

Sixty genetic loci associated with abdominal obesity, measured by waist circumference (WC) and waist-hip ratio (WHR), have been previously identified, primarily from studies conducted in European-ancestry populations. We conducted a meta-analysis of associations of abdominal obesity with approximately 2.5 million single nucleotide polymorphisms (SNPs) among 53,052 (for WC) and 48,312 (for WHR) individuals of Asian descent, and replicated 33 selected SNPs among 3,762 to 17,110 additional individuals. We identified four novel loci near the EFEMP1, ADAMTSL3 , CNPY2, and GNAS genes that were associated with WC after adjustment for body mass index (BMI); two loci near the NID2 and HLA-DRB5 genes associated with WHR after adjustment for BMI, and three loci near the CEP120, TSC22D2, and SLC22A2 genes associated with WC without adjustment for BMI. Functional enrichment analyses revealed enrichment of corticotropin-releasing hormone signaling, GNRH signaling, and/or CDK5 signaling pathways for those newly-identified loci. Our study provides additional insight on genetic contribution to abdominal obesity. PMID:26785701

IFP35 Is Involved in the Antiviral Function of Interferon by Association with the Viral Tas Transactivator of Bovine Foamy Virus▿

PubMed Central

Tan, Juan; Qiao, Wentao; Wang, Jian; Xu, Fengwen; Li, Yue; Zhou, Jun; Chen, Qimin; Geng, Yunqi

2008-01-01

Interferon-induced proteins (IFPs) exert multiple functions corresponding to diverse interferon signals. However, the intracellular functions of many IFPs are not fully characterized. Here, we report that IFP35, a member of the IFP family with a molecular mass of 35 kDa, can interact with the bovine Tas (BTas) regulatory protein of bovine foamy virus (BFV). The interaction involves NID2 (IFP35/Nmi homology domain) of IFP35 and the central domain of BTas. The overexpression of IFP35 disturbs the ability of BTas to activate viral-gene transcription and inhibits viral replication. The depletion of endogenous IFP35 by interfering RNA can promote the activation of BFV, suggesting an inhibitory function of IFP35 in viral-gene expression. In addition, IFP35 can interact with the homologous regulatory protein of prototype FV and arrest viral replication and repress viral transcription. Our study suggests that IFP35 may represent a novel pathway of interferon-mediated antiviral activity in host organisms that plays a role in the maintenance of FV latency. PMID:18305040

Corrosion of Alloy 690 process pot by sulfate containing high level radioactive waste at feed stage

NASA Astrophysics Data System (ADS)

Sengupta, P.; Soudamini, N.; Kaushik, C. P.; Jagannath; Mishra, R. K.; Kale, G. B.; Raj, K.; Das, D.; Sharma, B. P.

2008-02-01

Prolonged exposure of Alloy 690 process pot to sulfate containing high level radioactive waste leads to (a) depletion of Cr from the alloy, (b) intergranular attack and (c) building up of Cr 2O 3-Ni 2O 3-Fe 2O 3 mixed oxide surface layer containing Na and Cs sulfate precipitates. Time dependence of material loss from Alloy 690 is found to follow a linear relationship of the type Δ w (material loss) = -7.05 + 0.05 t. Corrosion rate calculated for 2400 h exposure is 3.66 mpy. Cr and Ni leach rates obtained for the same sample are 1.61 g m -2 d -1 and 2.52 g m -2 d -1, respectively. Ni leach rates followed a linear time dependence relationship of the type dNL Ni/d t (leach rate) = -0.09 + 0.027 t, whereas Cr leach rates obeyed a non-linear relationship of the type dNL Cr/d t (leach rate) = 0.241 + 0.027 t - 1.33 × 10 -4t1/2.

[Comparison of HbA1c, fructosamine and the main metabolic parameters in a non-insulin-dependent diabetic population].

PubMed

Magnati, G; Arsenio, L; Baroni, M C; Bodria, P; Bossi, S; Delsignore, R; Ippolito, L; Mineo, F; Strata, A

1990-01-01

Our objective was the checking of clinical data obtainable from the assay of some parameters in NID diabetic individuals. To this end, we studied 133 patients--57 males and 76 females, average age 74.36 +/- 1.01 years, 72.6% of which were above 65 years of age. The control population was subdivided as follows: 50 subjects, 26 F and 24 M; average age 71.25 +/- 1.32 years, with normal glucidic tolerance as assessed by OGTT. Current glycemia, average glycemia, fructosamine, glycosylated hemoglobin, triglycerides, LDL-cholesterol and apolipoprotein B were obviously much higher than normal in the individuals admitted to the study. A statistically significant correlation was found between average glycemia, glycosylated hemoglobin, LDL-cholesterol and blood triglycerides (p less than 0.05). No correlation was found between current glycemia, fructosamine and glycosylated hemoglobin. Similarly, serum fructosamine was unrelated to the parameters studied. In our study, fructosamine, glycosylated hemoglobin and current glycemia offered unrelatable data. Hence, in our opinion it is necessary to assay these three parameters contemporaneously for a reliable assessment of metabolic compensation.

Urine cell-based DNA methylation classifier for monitoring bladder cancer.

PubMed

van der Heijden, Antoine G; Mengual, Lourdes; Ingelmo-Torres, Mercedes; Lozano, Juan J; van Rijt-van de Westerlo, Cindy C M; Baixauli, Montserrat; Geavlete, Bogdan; Moldoveanud, Cristian; Ene, Cosmin; Dinney, Colin P; Czerniak, Bogdan; Schalken, Jack A; Kiemeney, Lambertus A L M; Ribal, Maria J; Witjes, J Alfred; Alcaraz, Antonio

2018-01-01

Current standard methods used to detect and monitor bladder cancer (BC) are invasive or have low sensitivity. This study aimed to develop a urine methylation biomarker classifier for BC monitoring and validate this classifier in patients in follow-up for bladder cancer (PFBC). Voided urine samples ( N  = 725) from BC patients, controls, and PFBC were prospectively collected in four centers. Finally, 626 urine samples were available for analysis. DNA was extracted from the urinary cells and bisulfite modificated, and methylation status was analyzed using pyrosequencing. Cytology was available from a subset of patients ( N  = 399). In the discovery phase, seven selected genes from the literature ( CDH13 , CFTR , NID2 , SALL3 , TMEFF2 , TWIST1 , and VIM2 ) were studied in 111 BC and 57 control samples. This training set was used to develop a gene classifier by logistic regression and was validated in 458 PFBC samples (173 with recurrence). A three-gene methylation classifier containing CFTR , SALL3 , and TWIST1 was developed in the training set (AUC 0.874). The classifier achieved an AUC of 0.741 in the validation series. Cytology results were available for 308 samples from the validation set. Cytology achieved AUC 0.696 whereas the classifier in this subset of patients reached an AUC 0.768. Combining the methylation classifier with cytology results achieved an AUC 0.86 in the validation set, with a sensitivity of 96%, a specificity of 40%, and a positive and negative predictive value of 56 and 92%, respectively. The combination of the three-gene methylation classifier and cytology results has high sensitivity and high negative predictive value in a real clinical scenario (PFBC). The proposed classifier is a useful test for predicting BC recurrence and decrease the number of cystoscopies in the follow-up of BC patients. If only patients with a positive combined classifier result would be cystoscopied, 36% of all cystoscopies can be prevented.

Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.

PubMed

Spracklen, Cassandra N; Chen, Peng; Kim, Young Jin; Wang, Xu; Cai, Hui; Li, Shengxu; Long, Jirong; Wu, Ying; Wang, Ya Xing; Takeuchi, Fumihiko; Wu, Jer-Yuarn; Jung, Keum-Ji; Hu, Cheng; Akiyama, Koichi; Zhang, Yonghong; Moon, Sanghoon; Johnson, Todd A; Li, Huaixing; Dorajoo, Rajkumar; He, Meian; Cannon, Maren E; Roman, Tamara S; Salfati, Elias; Lin, Keng-Hung; Guo, Xiuqing; Sheu, Wayne H H; Absher, Devin; Adair, Linda S; Assimes, Themistocles L; Aung, Tin; Cai, Qiuyin; Chang, Li-Ching; Chen, Chien-Hsiun; Chien, Li-Hsin; Chuang, Lee-Ming; Chuang, Shu-Chun; Du, Shufa; Fan, Qiao; Fann, Cathy S J; Feranil, Alan B; Friedlander, Yechiel; Gordon-Larsen, Penny; Gu, Dongfeng; Gui, Lixuan; Guo, Zhirong; Heng, Chew-Kiat; Hixson, James; Hou, Xuhong; Hsiung, Chao Agnes; Hu, Yao; Hwang, Mi Yeong; Hwu, Chii-Min; Isono, Masato; Juang, Jyh-Ming Jimmy; Khor, Chiea-Chuen; Kim, Yun Kyoung; Koh, Woon-Puay; Kubo, Michiaki; Lee, I-Te; Lee, Sun-Ju; Lee, Wen-Jane; Liang, Kae-Woei; Lim, Blanche; Lim, Sing-Hui; Liu, Jianjun; Nabika, Toru; Pan, Wen-Harn; Peng, Hao; Quertermous, Thomas; Sabanayagam, Charumathi; Sandow, Kevin; Shi, Jinxiu; Sun, Liang; Tan, Pok Chien; Tan, Shu-Pei; Taylor, Kent D; Teo, Yik-Ying; Toh, Sue-Anne; Tsunoda, Tatsuhiko; van Dam, Rob M; Wang, Aili; Wang, Feijie; Wang, Jie; Wei, Wen Bin; Xiang, Yong-Bing; Yao, Jie; Yuan, Jian-Min; Zhang, Rong; Zhao, Wanting; Chen, Yii-Der Ida; Rich, Stephen S; Rotter, Jerome I; Wang, Tzung-Dau; Wu, Tangchun; Lin, Xu; Han, Bok-Ghee; Tanaka, Toshihiro; Cho, Yoon Shin; Katsuya, Tomohiro; Jia, Weiping; Jee, Sun-Ha; Chen, Yuan-Tsong; Kato, Norihiro; Jonas, Jost B; Cheng, Ching-Yu; Shu, Xiao-Ou; He, Jiang; Zheng, Wei; Wong, Tien-Yin; Huang, Wei; Kim, Bong-Jo; Tai, E-Shyong; Mohlke, Karen L; Sim, Xueling

2017-05-01

Large-scale meta-analyses of genome-wide association studies (GWAS) have identified >175 loci associated with fasting cholesterol levels, including total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), and triglycerides (TG). With differences in linkage disequilibrium (LD) structure and allele frequencies between ancestry groups, studies in additional large samples may detect new associations. We conducted staged GWAS meta-analyses in up to 69,414 East Asian individuals from 24 studies with participants from Japan, the Philippines, Korea, China, Singapore, and Taiwan. These meta-analyses identified (P < 5 × 10-8) three novel loci associated with HDL-C near CD163-APOBEC1 (P = 7.4 × 10-9), NCOA2 (P = 1.6 × 10-8), and NID2-PTGDR (P = 4.2 × 10-8), and one novel locus associated with TG near WDR11-FGFR2 (P = 2.7 × 10-10). Conditional analyses identified a second signal near CD163-APOBEC1. We then combined results from the East Asian meta-analysis with association results from up to 187,365 European individuals from the Global Lipids Genetics Consortium in a trans-ancestry meta-analysis. This analysis identified (log10Bayes Factor ≥6.1) eight additional novel lipid loci. Among the twelve total loci identified, the index variants at eight loci have demonstrated at least nominal significance with other metabolic traits in prior studies, and two loci exhibited coincident eQTLs (P < 1 × 10-5) in subcutaneous adipose tissue for BPTF and PDGFC. Taken together, these analyses identified multiple novel lipid loci, providing new potential therapeutic targets. © The Author 2017. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

Protein-protein interaction network of gene expression in the hydrocortisone-treated keloid.

PubMed

Chen, Rui; Zhang, Zhiliang; Xue, Zhujia; Wang, Lin; Fu, Mingang; Lu, Yi; Bai, Ling; Zhang, Ping; Fan, Zhihong

2015-01-01

In order to explore the molecular mechanism of hydrocortisone in keloid tissue, the gene expression profiles of keloid samples treated with hydrocortisone were subjected to bioinformatics analysis. Firstly, the gene expression profiles (GSE7890) of five samples of keloid treated with hydrocortisone and five untreated keloid samples were downloaded from the Gene Expression Omnibus (GEO) database. Secondly, data were preprocessed using packages in R language and differentially expressed genes (DEGs) were screened using a significance analysis of microarrays (SAM) protocol. Thirdly, the DEGs were subjected to gene ontology (GO) function and KEGG pathway enrichment analysis. Finally, the interactions of DEGs in samples of keloid treated with hydrocortisone were explored in a human protein-protein interaction (PPI) network, and sub-modules of the DEGs interaction network were analyzed using Cytoscape software. Based on the analysis, 572 DEGs in the hydrocortisone-treated samples were screened; most of these were involved in the signal transduction and cell cycle. Furthermore, three critical genes in the module, including COL1A1, NID1, and PRELP, were screened in the PPI network analysis. These findings enhance understanding of the pathogenesis of the keloid and provide references for keloid therapy. © 2015 The International Society of Dermatology.

Effect of Ambipolar Diffusion on Ion Abundances in Contracting Protostellar Cores

NASA Astrophysics Data System (ADS)

Ciolek, Glenn E.; Mouschovias, Telemachos Ch.

1998-09-01

Numerical simulations and analytical solutions have established that ambipolar diffusion can reduce the dust-to-gas ratio in magnetically and thermally supercritical cores during the epoch of core formation. We study the effect that this has on the ion chemistry in contracting protostellar cores and present a simplified analytical method that allows one to calculate the ion power-law exponent k (≡d ln ni/d ln nn, where ni and nn are the ion and neutral densities, respectively) as a function of core density. We find that, as in earlier numerical simulations, no single value of k can adequately describe the ion abundance for nn <~ 109 cm-3, a result that is contrary to the ``canonical'' value of k = 1/2 found in previous static equilibrium chemistry calculations and often used to study the effect of ambipolar diffusion in interstellar clouds. For typical cloud and grain parameters, reduction of the abundance of grains results in k > 1/2 during the core formation epoch (densities <~105 cm-3). As a consequence, observations of the degree of ionization in cores could be used, in principle, to determine whether ambipolar diffusion is responsible for core formation in interstellar molecular clouds. For densities >>105 cm-3, k is generally <<1/2.

In which preterm labor-patients is intravenous maintenance tocolysis effective?

PubMed

Yoneda, Satoshi; Yoneda, Noriko; Fukuta, Kaori; Shima, Tomoko; Nakashima, Akitoshi; Shiozaki, Arihiro; Yoshino, Osamu; Kigawa, Mika; Yoshida, Taketoshi; Saito, Shigeru

2018-03-01

We evaluated whether maintenance tocolysis (intravenous ritodrine hydrochloride and/or magnesium sulfate) was effective in cases of spontaneous preterm labor with intact membranes. One hundred and thirty preterm labor patients who reached 36 weeks of gestation by maintenance tocolysis were selected. Immediate delivery (ID) after ceasing maintenance tocolysis was defined as an 'effective case'. The correlated factors between ID and no immediate delivery (NID) were statistically analyzed. Thirty-six patients delivered < two days after ceasing maintenance tocolysis (27.7%) and were defined as effective cases. Multiple logistic regression analysis revealed that amniotic fluid interleukin-8 at admission (≥ 2.3 ng/mL; odds ratio [OR] 5.6, 95% confidence interval [CI] 2.1-17.6; P < 0.001), pre-pregnancy body mass index (≤ 21.4; OR 5.3, 95% CI 2.0-16.2; P < 0.001) and cerclage (OR 3.6, 95% CI 1.1-11.8; P = 0.028) were independent factors correlated with ID (< 2 days). Maintenance tocolysis may be effective in limited cases with mild intra-amniotic inflammation, in lean women and in cerclage cases. Maintenance tocolysis should be ceased in cases without these clinical factors when clinical symptoms disappear. © 2017 Japan Society of Obstetrics and Gynecology.

A single amino acid substitution in the Bombyx-specific mucin-like membrane protein causes resistance to Bombyx mori densovirus.

PubMed

Ito, Katsuhiko; Kidokoro, Kurako; Katsuma, Susumu; Sezutsu, Hideki; Uchino, Keiro; Kobayashi, Isao; Tamura, Toshiki; Yamamoto, Kimiko; Mita, Kazuei; Shimada, Toru; Kadono-Okuda, Keiko

2018-05-09

Bombyx mori densovirus type 1 (BmDV) is a pathogen that causes flacherie disease in the silkworm. The absolute nonsusceptibility to BmDV among certain silkworm strains is determined independently by two genes, nsd-1 and Nid-1. However, neither of these genes has been molecularly identified to date. Here, we isolated the nsd-1 gene by positional cloning and characterized the properties of its product, NSD-1. Sequence and biochemical analyses revealed that this gene encodes a Bombyx-specific mucin-like glycoprotein with a single transmembrane domain. The NSD-1 protein was specifically expressed in the larval midgut epithelium, the known infection site of BmDV. Sequence analysis of the nsd-1 gene from 13 resistant and 12 susceptible strains suggested that a specific arginine residue in the extracellular tail of the NSD-1 protein was common among susceptible strains. Germline transformation of the susceptible-type nsd-1 (with a single nucleotide substitution) conferred partial susceptibility to resistant larvae, indicating that the +  nsd-1 gene is required for the susceptibility of B. mori larvae to BmDV and the susceptibility is solely a result of the substitution of a single amino acid with arginine. Taken together, our results provide striking evidence that a novel membrane-bound mucin-like protein functions as a cell-surface receptor for a densovirus.

Depression, disability and functional status among community dwelling older adults in South Africa: Evidence from the first South African National Income Dynamics Study

PubMed Central

Tomita, Andrew; Burns, Jonathan K

2013-01-01

Objectives This study examined the relationship between depression and functional status among a community-dwelling elderly population of 65 years and older in South Africa. Method Data from the first wave of the South African National Income Dynamics Study (SA-NIDS) was used, this being the first longitudinal panel survey of a nationally representative sample of households. The study focused on the data for resident adults 65 years and older (n=1,429). Depression was assessed using the 10-item version of the Center for Epidemiologic Studies Depression Scale (CES-D). Functional status, pertaining to both difficulty and dependency in activities of daily living (ADL), instrumental activities of daily living (IADL), and physical functioning and mobility (PFM), were assessed using 11 items. Results Functional challenges were generally higher in the older age group. There was a significant association between depression and functional dependency in ADL (adjusted OR=2.57 [CI: 1.03-6.41]), IADL (adjusted OR=2.76 [CI: 1.89-4.04]) and PFM (adjusted OR=1.66 [CI: 1.18-2.33]) but the relationship between depression and functional status, particularly PFM, appeared weaker in older age. Conclusion The relationship between depression symptoms and function is complex. Functional characteristics between older and younger older populations are diverse, and caution is indicated against overgeneralizing the challenges related to depression and function among this target population. PMID:23512338

The time course of taste bud regeneration after glossopharyngeal or greater superficial petrosal nerve transection in rats.

PubMed

St John, Steven J; Garcea, Mircea; Spector, Alan C

2003-01-01

We previously have published data detailing the time course of taste bud regeneration in the anterior tongue following transection of the chorda tympani (CT) nerve in the rat. This study extends the prior work by determining the time course of taste bud regeneration in the vallate papilla, soft palate and nasoincisor ducts (NID) following transection of either the glossopharyngeal (GL) or greater superficial petrosal (GSP) nerve. Following GL transection in rats (n = 6 per time point), taste buds reappeared in the vallate papilla between 15 and 28 days after surgery, and returned to 80.3% of control levels (n = 12) of taste buds by 70 days postsurgery. The first appearance and the final percentage of the normal complement of regenerated vallate taste buds after GL transection resembled that seen previously in the anterior tongue after CT transection. However, in the latter case, regenerated taste buds reached asymptotic levels by 42 days after surgery, whereas within the time frame of the present study, a clear asymptotic return of vallate taste buds was not observed. In contrast to the posterior (and anterior) tongue, only 25% of the normal complement of palatal taste buds regenerated by 112 days and 224 days after GSP transection (n = 9). The difference in regenerative capacity might relate to the surgical approach used to transect the GSP. These experiments provide useful parametric data for investigators studying the functional consequences of gustatory nerve transection and regeneration.

Inferring genome-wide functional modulatory network: a case study on NF-κB/RelA transcription factor.

PubMed

Li, Xueling; Zhu, Min; Brasier, Allan R; Kudlicki, Andrzej S

2015-04-01

How different pathways lead to the activation of a specific transcription factor (TF) with specific effects is not fully understood. We model context-specific transcriptional regulation as a modulatory network: triplets composed of a TF, target gene, and modulator. Modulators usually affect the activity of a specific TF at the posttranscriptional level in a target gene-specific action mode. This action may be classified as enhancement, attenuation, or inversion of either activation or inhibition. As a case study, we inferred, from a large collection of expression profiles, all potential modulations of NF-κB/RelA. The predicted modulators include many proteins previously not reported as physically binding to RelA but with relevant functions, such as RNA processing, cell cycle, mitochondrion, ubiquitin-dependent proteolysis, and chromatin modification. Modulators from different processes exert specific prevalent action modes on distinct pathways. Modulators from noncoding RNA, RNA-binding proteins, TFs, and kinases modulate the NF-κB/RelA activity with specific action modes consistent with their molecular functions and modulation level. The modulatory networks of NF-κB/RelA in the context epithelial-mesenchymal transition (EMT) and burn injury have different modulators, including those involved in extracellular matrix (FBN1), cytoskeletal regulation (ACTN1), and metastasis-associated lung adenocarcinoma transcript 1 (MALAT1), a long intergenic nonprotein coding RNA, and tumor suppression (FOXP1) for EMT, and TXNIP, GAPDH, PKM2, IFIT5, LDHA, NID1, and TPP1 for burn injury.

Cardiovascular disease and ABO blood-groups in Africans. Are blood-group A individuals at higher risk of ischemic disease?: A pilot study.

PubMed

Ba, Djibril Marie; Sow, Mamadou Saidou; Diack, Aminata; Dia, Khadidiatou; Mboup, Mouhamed Cherif; Fall, Pape Diadie; Fall, Moussa Daouda

2017-12-01

Since the discovery of the ABO blood group system by Karl Landsteiner in 1901, several reports have suggested an important involvement of the ABO blood group system in the susceptibility to thrombosis. Assessing that non-O blood groups in particular A blood group confer a higher risk of venous and arterial thrombosis than group O.Epidemiologic data are typically not available for all racial and ethnics groups.The purpose of this pilot study was to identify a link between ABO blood group and ischemic disease (ID) in Africans, and to analyze whether A blood group individuals were at higher risk of ischemic disease or not. A total of 299 medical records of patients over a three-year period admitted to the cardiology and internal medicine department of military hospital of Ouakam in Senegal were reviewed. We studied data on age, gender, past history of hypertension, diabetes, smoking, sedentarism, obesity, hyperlipidemia, use of estrogen-progestin contraceptives and blood group distribution.In each blood group type, we evaluated the prevalence of ischemic and non-ischemic cardiovascular disease. The medical records were then stratified into two categories to evaluate incidence of ischemic disease: Group 1: Patients carrying blood-group A and Group 2: Patients carrying blood group non-A (O, AB and B). Of the 299 patients whose medical records were reviewed, 92 (30.8%) were carrying blood group A, 175 (58.5%) had blood group O, 13 (4.3%) had blood group B, and 19 (6.4%) had blood group AB.The diagnosis of ischemic disease (ID) was higher in patients with blood group A (61.2%) than in other blood groups, and the diagnosis of non-ischemic disease (NID) was higher in patients with blood group O (73.6%) compared to other groups. In patients with blood group B or AB compared to non-B or non-AB, respectively there was no statistically significant difference in ID incidence.Main risk factor for ID was smoking (56.5%), hypertension (18.4%) and diabetes (14.3%).In our study, there was no statistical difference between blood group A and non-A in myocardial infarction (MI) incidence ( p  = 0.09, 95% CI = 0.99-2.83) but a statistically significant difference between blood group A and non-A in stroke and coronary artery disease (CAD) incidence (p < 0.0001, 95% CI = 1.80-3.37 and p  < 0.0001 95% CI = 1.82-3.41 respectively) was found.The incidence of ID in men was significantly higher in blood group A (95% CI = 2.26-4.57, p  < 0.0001) compared with non-A group, while there was no statistically significant difference in women ( p  = 0.35). However, an overall effect was detected to be statistically significant regardless of gender ( p  < 0.0001). Our study suggests an association between blood group A and ID in sub-Sahara Africans.In African countries, where most of health facilities are understaffed, more rigorous studies with a larger population are needed to give a high level of evidence to confirm this association in order to establish the need to be more aggressive in risk factor control in these individuals.

A multilevel analysis of the relationship between neighborhood social disorder and depressive symptoms: Evidence from the South African National Income Dynamics Study

PubMed Central

Tomita, Andrew; Labys, Charlotte A.; Burns, Jonathan K

2015-01-01

The apartheid regime that governed South Africa from 1948 – 1994 established spatial segregation that is understood to have contributed to the magnitude of neighborhood social disorder in the post-apartheid era. Although a number of neighborhood social disorder characteristics, such as perceived violence and crime in the community, are prominent issues in South Africa, the extent to which these perceived spatial attributes are linked to depression is unknown at the population-level. Multilevel modeling of data from the second wave of the South African National Income Dynamics Study (SA-NIDS) was utilized to examine the relationship between depressive symptomatology and neighborhood social disorder as indicated by the perceived frequency of violent, criminal and illicit activities in the community. Depressive symptomatology was assessed using the 10-item version of the Center for Epidemiologic Studies Depression Scale. A cut off score of ten or higher was used to indicate the presence of significant depressive symptomatology. Results showed that perception of neighborhood social disorder was independently associated with significant levels of depressive symptomatology. Gender, race/ethnicity, perceived health status, and education were significant for individual-level covariates of depression. Community intervention strategies that reduce the risk of neighborhood disorganization and emphasize positive social norms in the neighborhood are warranted. Taking into account the residential de-racialization of a country transitioning from apartheid to non-racial democracy, a longitudinal spatial study design assessing the dynamics between depression and the aforementioned perceptions of neighborhood attributes may also be warranted. PMID:25642654

Geographic assessment of access to health care in patients with cardiovascular disease in South Africa.

PubMed

Kapwata, Thandi; Manda, Samuel

2018-03-22

Noncommunicable diseases (NCDs) including cardiovascular diseases (CVDs), diabetes, cancer and chronic lung disease are increasingly emerging as major contributors to morbidity and mortality in developing countries. For example, in South Africa, 195 people died per day between 1997 and 2004 from CVDs related causes. Access to efficient and effective health facility and care is an important contributing factor to overall population health and addressing prognosis, care and management CVD disease burden. This study aimed to spatially evaluate geographic health care access of people diagnosed with CVD to health facilities and to evaluate the density of the existing health facility network in South Africa. Data was obtained from the National Income Dynamics Study (NIDS) conducted in 4 waves (phases) between 2008 and 2014. The participants who responded as having heart problems that were diagnosed by a health practitioner were extracted for use in this study. Network analyst in ArcGIS ® was used to generate a least-cost path, which refers to the best path that one can travel. The residential locations of participants diagnosed with heart problems were put into the network analysis model as origins and the location of health facilities were destinations. District averages were used to protect the identity of studied participants. There were a total of 51, 42, 43, 43 health districts out the 52 that had recorded subjects with a heart condition in the 2008, 2010-2011, 2012 and 2014-2015 waves, respectively. The mean distance from a case household to a health facility per wave was 2, 2.3, 2.1 and 2.1 km in 2008, 2010-2011 and 2014-2015 respectively. The maximum individual distances travelled per wave were 41.4 km, 40,5 km, 44,2 km and 39.6 km for the 2008, 2010-2011, 2012 and 2014-2015 waves respectively. For district level analysis, participants with CVD residing in the districts found to be among the poorest in the country travelled the longest distances. These were located in the provinces of Limpopo and KwaZulu Natal. It was also found that districts with large proportions of their population living in rural settings had among the lowest densities of health facilities. Significant percentages of study participants were exposed to numerous CVD risk factors, the commonly reported one being high blood pressure. A lack of regular exercise was also commonly reported in each of the waves. A lack of accessible healthcare in already impoverished municipalities could result in an increase lack of timely diagnosis, CVD case management. This could result in increased CVD-related morbidity and mortality. GIS methods have the potential to assist national health programs to develop policies that target issues such as areas or populations being underserved by health facilities and populations that must travel long distances to receive healthcare. These policies will be key in preventing and controlling the emerging CVD burden through an accessible primary healthcare system for early detection and case management.

Generalized Detectability for Discrete Event Systems

PubMed Central

Shu, Shaolong; Lin, Feng

2011-01-01

In our previous work, we investigated detectability of discrete event systems, which is defined as the ability to determine the current and subsequent states of a system based on observation. For different applications, we defined four types of detectabilities: (weak) detectability, strong detectability, (weak) periodic detectability, and strong periodic detectability. In this paper, we extend our results in three aspects. (1) We extend detectability from deterministic systems to nondeterministic systems. Such a generalization is necessary because there are many systems that need to be modeled as nondeterministic discrete event systems. (2) We develop polynomial algorithms to check strong detectability. The previous algorithms are based on observer whose construction is of exponential complexity, while the new algorithms are based on a new automaton called detector. (3) We extend detectability to D-detectability. While detectability requires determining the exact state of a system, D-detectability relaxes this requirement by asking only to distinguish certain pairs of states. With these extensions, the theory on detectability of discrete event systems becomes more applicable in solving many practical problems. PMID:21691432

Point pattern match-based change detection in a constellation of previously detected objects

DOEpatents

Paglieroni, David W.

2016-06-07

A method and system is provided that applies attribute- and topology-based change detection to objects that were detected on previous scans of a medium. The attributes capture properties or characteristics of the previously detected objects, such as location, time of detection, detection strength, size, elongation, orientation, etc. The locations define a three-dimensional network topology forming a constellation of previously detected objects. The change detection system stores attributes of the previously detected objects in a constellation database. The change detection system detects changes by comparing the attributes and topological consistency of newly detected objects encountered during a new scan of the medium to previously detected objects in the constellation database. The change detection system may receive the attributes of the newly detected objects as the objects are detected by an object detection system in real time.

Research of the absorbance detection and fluorescence detection for multifunctional nutrition analyzer

NASA Astrophysics Data System (ADS)

Ni, Zhengyuan; Yan, Huimin; Ni, Xuxiang; Zhang, Xiuda

2017-10-01

The research of the multifunctional analyzer which integrates absorbance detection, fluorescence detection, time-resolved fluorescence detection, biochemical luminescence detection methods, can make efficient detection and analysis for a variety of human body nutrients. This article focuses on the absorbance detection and fluorescence detection system. The two systems are modular in design and controlled by embedded system, to achieve automatic measurement according to user settings. In the optical path design, the application of confocal design can improve the optical signal acquisition capability, and reduce the interference. A photon counter is used for detection, and a high performance counter module is designed to measure the output of photon counter. In the experiment, we use neutral density filters and potassium dichromate solution to test the absorbance detection system, and use fluorescein isothiocyanate FITC for fluorescence detection system performance test. The experimental results show that the absorbance detection system has a detection range of 0 4OD, and has good linearity in the detection range, while the fluorescence detection system has a high sensitivity of 1pmol/L concentration.

46 CFR 108.405 - Fire detection system.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 4 2010-10-01 2010-10-01 false Fire detection system. 108.405 Section 108.405 Shipping... EQUIPMENT Fire Extinguishing Systems § 108.405 Fire detection system. (a) Each fire detection system and each smoke detection system on a unit must— (1) Be approved by the Commandant; and (2) Have a visual...

Clinical Forms of Canine Visceral Leishmaniasis in Naturally Leishmania infantum–Infected Dogs and Related Myelogram and Hemogram Changes

PubMed Central

Roatt, Bruno Mendes; Aguiar-Soares, Rodrigo Dian de Oliveira; Reis, Levi Eduardo Soares; Carvalho, Maria das Graças; Carneiro, Cláudia Martins; Giunchetti, Rodolfo Cordeiro; Bouillet, Leoneide Erica Maduro; Lemos, Denise Silveira; Coura-Vital, Wendel; Reis, Alexandre Barbosa

2013-01-01

Hematological analysis has limited applications for disease diagnosis in Leishmania infantum–infected dogs, but it can be very important in evaluating the clinical forms of the disease and in understanding the evolution of canine visceral leishmaniasis (CVL) pathogenesis. Recently, we demonstrated that alterations in leucopoiesis and erythropoiesis are related to clinical status and bone marrow parasite density in dogs naturally infected by L. infantum. To further characterize these alterations, we evaluated the association between the hematological parameters in bone marrow and peripheral blood alterations in groups of L. infantum–infected dogs: asymptomatic I (AD-I: serum negative/PCR+), asymptomatic II (AD-II: serum positive), oligosymptomatic (OD), and symptomatic (SD). Results were compared with those from noninfected dogs (NID). The SD group was found to present a decrease in erythropoietic lineage with concomitant reductions in erythrocytes, hemoglobin, and hematocrit parameters, resulting in anemia. The SD group also had increased neutrophils and precursors and decreased band eosinophils and eosinophils, leading to peripheral blood leucopenia. In the AD-II group, lymphocytosis occurred in both the peripheral blood and the bone marrow compartments. The SD group exhibited lymphocytosis in the bone marrow, with lymphopenia in the peripheral blood. In contrast, the AD-I group, showed no significant changes suggestive of CVL, presenting normal counts in bone marrow and peripheral blood. Our results showed for the first time that important changes in hematopoiesis and hematological parameters occur during ongoing CVL in naturally infected dogs, mainly in symptomatic disease. Taken together, our results based on myelogram and hemogram parameters enable better understanding of the pathogenesis of the anemia, lymphocytosis, and lymphopenia, as well as the leucopenia (eosinopenia and monocytopenia), that contribute to CVL prognosis. PMID:24376612

Exposure estimate for FD&C colour additives for the US population.

PubMed

Doell, Diana L; Folmer, Daniel E; Lee, Hyoung S; Butts, Kyla M; Carberry, Susan E

2016-05-01

Dietary exposures to the seven food, drug, and cosmetic (FD&C) colour additives that are approved for general use in food in the United States were estimated for the US population (aged 2 years and older), children (aged 2-5 years) and teenage boys (aged 13-18 years) based on analytical levels of the FD&C colour additives in foods. Approximately 600 foods were chosen for analysis, based on a survey of product labels, for the levels of FD&C colour additives. Dietary exposure was estimated using both 2-day food consumption data from the combined 2007-10 National Health and Nutrition Examination Survey (NHANES) and 10-14-day food consumption data from the 2007-10 NPD Group, Inc. National Eating Trends - Nutrient Intake Database (NPD NET-NID). Dietary exposure was estimated at the mean and 90th percentile using three different exposure scenarios: low exposure, average exposure and high exposure, to account for the range in the amount of each FD&C colour additive for a given food. For all populations and all exposure scenarios, the highest cumulative eaters-only exposures in food were determined for FD&C Red No. 40, FD&C Yellow No. 5 and FD&C Yellow No. 6. In addition, the eaters-only exposure was estimated for individual food categories in order to determine which food categories contributed the most to the exposure for each FD&C colour additive. Breakfast Cereal, Juice Drinks, Soft Drinks, and Frozen Dairy Desserts/Sherbet (also referred to as Ice Cream, Frozen Yogurt, Sherbet (including Bars, Sticks, Sandwiches)) were the major contributing food categories to exposure for multiple FD&C colour additives for all three populations.

Effect of mixed soil microbiomes on pyrene removal and the response of the soil microorganisms.

PubMed

Wang, Beibei; Teng, Ying; Xu, Yongfeng; Chen, Wei; Ren, Wenjie; Li, Yan; Christie, Peter; Luo, Yongming

2018-05-28

Mixed soil microbiomes were established by introducing aliquots of a paddy soil into a red soil. The new mixed microbiomes effectively metabolized high-molecular-weight polycyclic aromatic hydrocarbons (PAHs, pyrene) in the soil mixtures. The pyrene removal efficiencies were 19% and 98%, respectively, in the original red soil and the paddy soil. The pyrene removal effectiveness by the mixed microbial community was enhanced by increasing the amount of paddy soil inoculant and the pyrene removal rates were 93%, 58% and 27% in paddy soil/red soil mixtures of 1:1, 3:7 and 1:9 (w/w), respectively. Supplementation with sterile paddy soil and nutrients changed the soil environment but the pyrene removal efficiency was not enhanced, indicating that the microbial composition largely determined the extent of pyrene removal. Moreover, the pyrene removal rate was positively related to the pyrene dioxygenase gene (nidA) abundance. The greater the percentage of the paddy soil in the soil mixture the greater the similarity of the mixed microbiome to that of the original paddy soil itself. The community of the inoculated sterile paddy soil was similar to that of the red soil and the community diverged from those of the red soil and the paddy soil with increasing culture time. After culture for 42 days, some enriched genera were responsible for PAH degradation, notably Nevskia, Ralstonia, Gemmatimonas and Lysobacter, while some genera have no clear classification information or category name at the genus level, such as f__Acidobacteriaceae and o__JG30-KF-AS9. This study is very important in recognizing the role of natural soil in the formation of a mixed microbiome to stimulate the degradation of PAHs in a soil with low intrinsic PAH degradation capability. Copyright © 2018 Elsevier B.V. All rights reserved.

Research Resource: Preovulatory LH Surge Effects on Follicular Theca and Granulosa Transcriptomes

PubMed Central

Gunewardena, Sumedha; Hong, Xiaoman; Spitschak, Marion; Baufeld, Anja

2013-01-01

The molecular mechanisms that regulate the pivotal transformation processes observed in the follicular wall following the preovulatory LH surge, are still not established, particularly for cells of the thecal layer. To elucidate thecal cell (TC) and granulosa cell (GC) type-specific biologic functions and signaling pathways, large dominant bovine follicles were collected before and 21 hours after an exogenous GnRH-induced LH surge. Antral GCs (aGCs; aspirated by follicular puncture) and membrane-associated GCs (mGCs; scraped from the follicular wall) were compared with TC expression profiles determined by mRNA microarrays. Of the approximately 11 000 total genes expressed in the periovulatory follicle, only 2% of thecal vs 25% of the granulosa genes changed in response to the LH surge. The majority of the 203 LH-regulated thecal genes were also LH regulated in GCs, leaving a total of 57 genes as LH-regulated TC-specific genes. Of the 57 thecal-specific LH-regulated genes, 74% were down-regulated including CYP17A1 and NR5A1, whereas most other genes are being identified for the first time within theca. Many of the newly identified up-regulated thecal genes (eg, PTX3, RND3, PPP4R4) were also up-regulated in granulosa. Minimal expression differences were observed between aGCs and mGCs; however, transcripts encoding extracellular proteins (NID2) and matrix modulators (ADAMTS1, SASH1) dominated these differences. We also identified large numbers of unknown LH-regulated GC genes and discuss their putative roles in ovarian function. This Research Resource provides an easy-to-access global evaluation of LH regulation in TCs and GCs that implicates numerous molecular pathways heretofore unknown within the follicle. PMID:23716604

Research resource: preovulatory LH surge effects on follicular theca and granulosa transcriptomes.

PubMed

Christenson, Lane K; Gunewardena, Sumedha; Hong, Xiaoman; Spitschak, Marion; Baufeld, Anja; Vanselow, Jens

2013-07-01

The molecular mechanisms that regulate the pivotal transformation processes observed in the follicular wall following the preovulatory LH surge, are still not established, particularly for cells of the thecal layer. To elucidate thecal cell (TC) and granulosa cell (GC) type-specific biologic functions and signaling pathways, large dominant bovine follicles were collected before and 21 hours after an exogenous GnRH-induced LH surge. Antral GCs (aGCs; aspirated by follicular puncture) and membrane-associated GCs (mGCs; scraped from the follicular wall) were compared with TC expression profiles determined by mRNA microarrays. Of the approximately 11 000 total genes expressed in the periovulatory follicle, only 2% of thecal vs 25% of the granulosa genes changed in response to the LH surge. The majority of the 203 LH-regulated thecal genes were also LH regulated in GCs, leaving a total of 57 genes as LH-regulated TC-specific genes. Of the 57 thecal-specific LH-regulated genes, 74% were down-regulated including CYP17A1 and NR5A1, whereas most other genes are being identified for the first time within theca. Many of the newly identified up-regulated thecal genes (eg, PTX3, RND3, PPP4R4) were also up-regulated in granulosa. Minimal expression differences were observed between aGCs and mGCs; however, transcripts encoding extracellular proteins (NID2) and matrix modulators (ADAMTS1, SASH1) dominated these differences. We also identified large numbers of unknown LH-regulated GC genes and discuss their putative roles in ovarian function. This Research Resource provides an easy-to-access global evaluation of LH regulation in TCs and GCs that implicates numerous molecular pathways heretofore unknown within the follicle.

Exposure estimate for FD&C colour additives for the US population

PubMed Central

Folmer, Daniel E.; Lee, Hyoung S.; Butts, Kyla M.; Carberry, Susan E.

2016-01-01

Dietary exposures to the seven food, drug, and cosmetic (FD&C) colour additives that are approved for general use in food in the United States were estimated for the US population (aged 2 years and older), children (aged 2–5 years) and teenage boys (aged 13–18 years) based on analytical levels of the FD&C colour additives in foods. Approximately 600 foods were chosen for analysis, based on a survey of product labels, for the levels of FD&C colour additives. Dietary exposure was estimated using both 2-day food consumption data from the combined 2007–10 National Health and Nutrition Examination Survey (NHANES) and 10–14-day food consumption data from the 2007–10 NPD Group, Inc. National Eating Trends – Nutrient Intake Database (NPD NET-NID). Dietary exposure was estimated at the mean and 90th percentile using three different exposure scenarios: low exposure, average exposure and high exposure, to account for the range in the amount of each FD&C colour additive for a given food. For all populations and all exposure scenarios, the highest cumulative eaters-only exposures in food were determined for FD&C Red No. 40, FD&C Yellow No. 5 and FD&C Yellow No. 6. In addition, the eaters-only exposure was estimated for individual food categories in order to determine which food categories contributed the most to the exposure for each FD&C colour additive. Breakfast Cereal, Juice Drinks, Soft Drinks, and Frozen Dairy Desserts/Sherbet (also referred to as Ice Cream, Frozen Yogurt, Sherbet (including Bars, Sticks, Sandwiches)) were the major contributing food categories to exposure for multiple FD&C colour additives for all three populations. PMID:27092991

Raising gestational choline intake alters gene expression in DMBA-evoked mammary tumors and prolongs survival.

PubMed

Kovacheva, Vesela P; Davison, Jessica M; Mellott, Tiffany J; Rogers, Adrianne E; Yang, Shi; O'Brien, Michael J; Blusztajn, Jan Krzysztof

2009-04-01

Choline is an essential nutrient that serves as a donor of metabolic methyl groups used during gestation to establish the epigenetic DNA methylation patterns that modulate tissue-specific gene expression. Because the mammary gland begins its development prenatally, we hypothesized that choline availability in utero may affect the gland's susceptibility to cancer. During gestational days 11-17, pregnant rats were fed a control, choline-supplemented, or choline-deficient diet (8, 36, and 0 mmol/kg of choline, respectively). On postnatal day 65, the female offspring received 25 mg/kg of a carcinogen 7,12-dimethylbenz[alpha]anthracene. Approximately 70% of the rats developed mammary adenocarcinomas; prenatal diet did not affect tumor latency, incidence, size, and multiplicity. Tumor growth rate was inversely related to choline content in the prenatal diet, resulting in 50% longer survival until euthanasia, determined by tumor size, of the prenatally choline-supplemented rats compared with the prenatally choline-deficient rats. This was accompanied by distinct expression patterns of approximately 70 genes in tumors derived from the three dietary groups. Tumors from the prenatally choline-supplemented rats overexpressed genes that confer favorable prognosis in human cancers (Klf6, Klf9, Nid2, Ntn4, Per1, and Txnip) and underexpressed those associated with aggressive disease (Bcar3, Cldn12, Csf1, Jag1, Lgals3, Lypd3, Nme1, Ptges2, Ptgs1, and Smarcb1). DNA methylation within the tumor suppressor gene, stratifin (Sfn, 14-3-3sigma), was proportional to the prenatal choline supply and correlated inversely with the expression of its mRNA and protein in tumors, suggesting that an epigenetic mechanism may underlie the altered molecular phenotype and tumor growth. Our results suggest a role for adequate maternal choline nutrition during pregnancy in prevention/alleviation of breast cancer in daughters.

Imaging, object detection, and change detection with a polarized multistatic GPR array

DOE Office of Scientific and Technical Information (OSTI.GOV)

Beer, N. Reginald; Paglieroni, David W.

A polarized detection system performs imaging, object detection, and change detection factoring in the orientation of an object relative to the orientation of transceivers. The polarized detection system may operate on one of several modes of operation based on whether the imaging, object detection, or change detection is performed separately for each transceiver orientation. In combined change mode, the polarized detection system performs imaging, object detection, and change detection separately for each transceiver orientation, and then combines changes across polarizations. In combined object mode, the polarized detection system performs imaging and object detection separately for each transceiver orientation, and thenmore » combines objects across polarizations and performs change detection on the result. In combined image mode, the polarized detection system performs imaging separately for each transceiver orientation, and then combines images across polarizations and performs object detection followed by change detection on the result.« less

Intrusion Detection in Control Systems using Sequence Characteristics

NASA Astrophysics Data System (ADS)

Kiuchi, Mai; Onoda, Takashi

Intrusion detection is considered effective in control systems. Sequences of the control application behavior observed in the communication, such as the order of the control device to be controlled, are important in control systems. However, most intrusion detection systems do not effectively reflect sequences in the application layer into the detection rules. In our previous work, we considered utilizing sequences for intrusion detection in control systems, and demonstrated the usefulness of sequences for intrusion detection. However, manually writing the detection rules for a large system can be difficult, so using machine learning methods becomes feasible. Also, in the case of control systems, there have been very few observed cyber attacks, so we have very little knowledge of the attack data that should be used to train the intrusion detection system. In this paper, we use an approach that combines CRF (Conditional Random Field) considering the sequence of the system, thus able to reflect the characteristics of control system sequences into the intrusion detection system, and also does not need the knowledge of attack data to construct the detection rules.

Supporting the Development and Adoption of Automatic Lameness Detection Systems in Dairy Cattle: Effect of System Cost and Performance on Potential Market Shares

PubMed Central

Van Weyenberg, Stephanie; Van Nuffel, Annelies; Lauwers, Ludwig; Vangeyte, Jürgen

2017-01-01

Simple Summary Most prototypes of systems to automatically detect lameness in dairy cattle are still not available on the market. Estimating their potential adoption rate could support developers in defining development goals towards commercially viable and well-adopted systems. We simulated the potential market shares of such prototypes to assess the effect of altering the system cost and detection performance on the potential adoption rate. We found that system cost and lameness detection performance indeed substantially influence the potential adoption rate. In order for farmers to prefer automatic detection over current visual detection, the usefulness that farmers attach to a system with specific characteristics should be higher than that of visual detection. As such, we concluded that low system costs and high detection performances are required before automatic lameness detection systems become applicable in practice. Abstract Most automatic lameness detection system prototypes have not yet been commercialized, and are hence not yet adopted in practice. Therefore, the objective of this study was to simulate the effect of detection performance (percentage missed lame cows and percentage false alarms) and system cost on the potential market share of three automatic lameness detection systems relative to visual detection: a system attached to the cow, a walkover system, and a camera system. Simulations were done using a utility model derived from survey responses obtained from dairy farmers in Flanders, Belgium. Overall, systems attached to the cow had the largest market potential, but were still not competitive with visual detection. Increasing the detection performance or lowering the system cost led to higher market shares for automatic systems at the expense of visual detection. The willingness to pay for extra performance was €2.57 per % less missed lame cows, €1.65 per % less false alerts, and €12.7 for lame leg indication, respectively. The presented results could be exploited by system designers to determine the effect of adjustments to the technology on a system’s potential adoption rate. PMID:28991188

46 CFR 161.002-2 - Types of fire-protective systems.

Code of Federal Regulations, 2013 CFR

2013-10-01

..., but not be limited to, automatic fire and smoke detecting systems, manual fire alarm systems, sample extraction smoke detection systems, watchman's supervisory systems, and combinations of these systems. (b) Automatic fire detecting systems. For the purpose of this subpart, automatic fire and smoke detecting...

46 CFR 161.002-2 - Types of fire-protective systems.

Code of Federal Regulations, 2014 CFR

2014-10-01

..., but not be limited to, automatic fire and smoke detecting systems, manual fire alarm systems, sample extraction smoke detection systems, watchman's supervisory systems, and combinations of these systems. (b) Automatic fire detecting systems. For the purpose of this subpart, automatic fire and smoke detecting...

Detection probability of an in-stream passive integrated transponder (PIT) tag detection system for juvenile salmonids in the Klamath River, northern California, 2011

USGS Publications Warehouse

Beeman, John W.; Hayes, Brian; Wright, Katrina

2012-01-01

A series of in-stream passive integrated transponder (PIT) detection antennas installed across the Klamath River in August 2010 were tested using tagged fish in the summer of 2011. Six pass-by antennas were constructed and anchored to the bottom of the Klamath River at a site between the Shasta and Scott Rivers. Two of the six antennas malfunctioned during the spring of 2011 and two pass-through antennas were installed near the opposite shoreline prior to system testing. The detection probability of the PIT tag detection system was evaluated using yearling coho salmon implanted with a PIT tag and a radio transmitter and then released into the Klamath River slightly downstream of Iron Gate Dam. Cormack-Jolly-Seber capture-recapture methods were used to estimate the detection probability of the PIT tag detection system based on detections of PIT tags there and detections of radio transmitters at radio-telemetry detection systems downstream. One of the 43 PIT- and radio-tagged fish released was detected by the PIT tag detection system and 23 were detected by the radio-telemetry detection systems. The estimated detection probability of the PIT tag detection system was 0.043 (standard error 0.042). Eight PIT-tagged fish from other studies also were detected. Detections at the PIT tag detection system were at the two pass-through antennas and the pass-by antenna adjacent to them. Above average river discharge likely was a factor in the low detection probability of the PIT tag detection system. High discharges dislodged two power cables leaving 12 meters of the river width unsampled for PIT detections and resulted in water depths greater than the read distance of the antennas, which allowed fish to pass over much of the system with little chance of being detected. Improvements in detection probability may be expected under river discharge conditions where water depth over the antennas is within maximum read distance of the antennas. Improvements also may be expected if additional arrays of antennas are used.

The design method and research status of vehicle detection system based on geomagnetic detection principle

NASA Astrophysics Data System (ADS)

Lin, Y. H.; Bai, R.; Qian, Z. H.

2018-03-01

Vehicle detection systems are applied to obtain real-time information of vehicles, realize traffic control and reduce traffic pressure. This paper reviews geomagnetic sensors as well as the research status of the vehicle detection system. Presented in the paper are also our work on the vehicle detection system, including detection algorithms and experimental results. It is found that the GMR based vehicle detection system has a detection accuracy up to 98% with a high potential for application in the road traffic control area.

Detection technique of targets for missile defense system

NASA Astrophysics Data System (ADS)

Guo, Hua-ling; Deng, Jia-hao; Cai, Ke-rong

2009-11-01

Ballistic missile defense system (BMDS) is a weapon system for intercepting enemy ballistic missiles. It includes ballistic-missile warning system, target discrimination system, anti-ballistic-missile guidance systems, and command-control communication system. Infrared imaging detection and laser imaging detection are widely used in BMDS for surveillance, target detection, target tracking, and target discrimination. Based on a comprehensive review of the application of target-detection techniques in the missile defense system, including infrared focal plane arrays (IRFPA), ground-based radar detection technology, 3-dimensional imaging laser radar with a photon counting avalanche photodiode (APD) arrays and microchip laser, this paper focuses on the infrared and laser imaging detection techniques in missile defense system, as well as the trends for their future development.

Detection of cat-eye effect echo based on unit APD

NASA Astrophysics Data System (ADS)

Wu, Dong-Sheng; Zhang, Peng; Hu, Wen-Gang; Ying, Jia-Ju; Liu, Jie

2016-10-01

The cat-eye effect echo of optical system can be detected based on CCD, but the detection range is limited within several kilometers. In order to achieve long-range even ultra-long-range detection, it ought to select APD as detector because of the high sensitivity of APD. The detection system of cat-eye effect echo based on unit APD is designed in paper. The implementation scheme and key technology of the detection system is presented. The detection performances of the detection system including detection range, detection probability and false alarm probability are modeled. Based on the model, the performances of the detection system are analyzed using typical parameters. The results of numerical calculation show that the echo signal-to-noise ratio is greater than six, the detection probability is greater than 99.9% and the false alarm probability is less tan 0.1% within 20 km detection range. In order to verify the detection effect, we built the experimental platform of detection system according to the design scheme and carry out the field experiments. The experimental results agree well with the results of numerical calculation, which prove that the detection system based on the unit APD is feasible to realize remote detection for cat-eye effect echo.

46 CFR 27.203 - What are the requirements for fire detection on towing vessels?

Code of Federal Regulations, 2010 CFR

2010-10-01

... detection on towing vessels? You must have a fire-detection system installed on your vessel to detect engine... use an existing engine-room-monitoring system (with fire-detection capability) instead of a fire-detection system, if the monitoring system is operable and complies with this section. You must ensure that...

Fusion of local and global detection systems to detect tuberculosis in chest radiographs.

PubMed

Hogeweg, Laurens; Mol, Christian; de Jong, Pim A; Dawson, Rodney; Ayles, Helen; van Ginneken, Bramin

2010-01-01

Automatic detection of tuberculosis (TB) on chest radiographs is a difficult problem because of the diverse presentation of the disease. A combination of detection systems for abnormalities and normal anatomy is used to improve detection performance. A textural abnormality detection system operating at the pixel level is combined with a clavicle detection system to suppress false positive responses. The output of a shape abnormality detection system operating at the image level is combined in a next step to further improve performance by reducing false negatives. Strategies for combining systems based on serial and parallel configurations were evaluated using the minimum, maximum, product, and mean probability combination rules. The performance of TB detection increased, as measured using the area under the ROC curve, from 0.67 for the textural abnormality detection system alone to 0.86 when the three systems were combined. The best result was achieved using the sum and product rule in a parallel combination of outputs.

Development of a HIV-1 Virus Detection System Based on Nanotechnology.

PubMed

Lee, Jin-Ho; Oh, Byung-Keun; Choi, Jeong-Woo

2015-04-27

Development of a sensitive and selective detection system for pathogenic viral agents is essential for medical healthcare from diagnostics to therapeutics. However, conventional detection systems are time consuming, resource-intensive and tedious to perform. Hence, the demand for sensitive and selective detection system for virus are highly increasing. To attain this aim, different aspects and techniques have been applied to develop virus sensor with improved sensitivity and selectivity. Here, among those aspects and techniques, this article reviews HIV virus particle detection systems incorporated with nanotechnology to enhance the sensitivity. This review mainly focused on four different detection system including vertically configured electrical detection based on scanning tunneling microscopy (STM), electrochemical detection based on direct electron transfer in virus, optical detection system based on localized surface plasmon resonance (LSPR) and surface enhanced Raman spectroscopy (SERS) using plasmonic nanoparticle.

46 CFR 108.413 - Fusible element fire detection system.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 4 2010-10-01 2010-10-01 false Fusible element fire detection system. 108.413 Section... UNITS DESIGN AND EQUIPMENT Fire Extinguishing Systems § 108.413 Fusible element fire detection system. (a) A fusible element fire detection system may be installed. (b) The arrangements for the system...

An immunity-based anomaly detection system with sensor agents.

PubMed

Okamoto, Takeshi; Ishida, Yoshiteru

2009-01-01

This paper proposes an immunity-based anomaly detection system with sensor agents based on the specificity and diversity of the immune system. Each agent is specialized to react to the behavior of a specific user. Multiple diverse agents decide whether the behavior is normal or abnormal. Conventional systems have used only a single sensor to detect anomalies, while the immunity-based system makes use of multiple sensors, which leads to improvements in detection accuracy. In addition, we propose an evaluation framework for the anomaly detection system, which is capable of evaluating the differences in detection accuracy between internal and external anomalies. This paper focuses on anomaly detection in user's command sequences on UNIX-like systems. In experiments, the immunity-based system outperformed some of the best conventional systems.

Nucleic acid detection system and method for detecting influenza

DOEpatents

Cai, Hong; Song, Jian

2015-03-17

The invention provides a rapid, sensitive and specific nucleic acid detection system which utilizes isothermal nucleic acid amplification in combination with a lateral flow chromatographic device, or DNA dipstick, for DNA-hybridization detection. The system of the invention requires no complex instrumentation or electronic hardware, and provides a low cost nucleic acid detection system suitable for highly sensitive pathogen detection. Hybridization to single-stranded DNA amplification products using the system of the invention provides a sensitive and specific means by which assays can be multiplexed for the detection of multiple target sequences.

The estimation method on diffusion spot energy concentration of the detection system

NASA Astrophysics Data System (ADS)

Gao, Wei; Song, Zongxi; Liu, Feng; Dan, Lijun; Sun, Zhonghan; Du, Yunfei

2016-09-01

We propose a method to estimate the diffusion spot energy of the detection system. We do outdoor observation experiments in Xinglong Observatory, by using a detection system which diffusion spot energy concentration is estimated (the correlation coefficient is approximate 0.9926).The aperture of system is 300mm and limiting magnitude of system is 14.15Mv. Observation experiments show that the highest detecting magnitude of estimated system is 13.96Mv, and the average detecting magnitude of estimated system is about 13.5Mv. The results indicate that this method can be used to evaluate the energy diffusion spot concentration level of detection system efficiently.

46 CFR 108.411 - Smoke detection system.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 4 2010-10-01 2010-10-01 false Smoke detection system. 108.411 Section 108.411 Shipping... EQUIPMENT Fire Extinguishing Systems § 108.411 Smoke detection system. Each smoke accumulator in a smoke detection system must be located on the overhead of the compartment protected by the system in a location...

The simulation study on optical target laser active detection performance

NASA Astrophysics Data System (ADS)

Li, Ying-chun; Hou, Zhao-fei; Fan, Youchen

2014-12-01

According to the working principle of laser active detection system, the paper establishes the optical target laser active detection simulation system, carry out the simulation study on the detection process and detection performance of the system. For instance, the performance model such as the laser emitting, the laser propagation in the atmosphere, the reflection of optical target, the receiver detection system, the signal processing and recognition. We focus on the analysis and modeling the relationship between the laser emitting angle and defocus amount and "cat eye" effect echo laser in the reflection of optical target. Further, in the paper some performance index such as operating range, SNR and the probability of the system have been simulated. The parameters including laser emitting parameters, the reflection of the optical target and the laser propagation in the atmosphere which make a great influence on the performance of the optical target laser active detection system. Finally, using the object-oriented software design methods, the laser active detection system with the opening type, complete function and operating platform, realizes the process simulation that the detection system detect and recognize the optical target, complete the performance simulation of each subsystem, and generate the data report and the graph. It can make the laser active detection system performance models more intuitive because of the visible simulation process. The simulation data obtained from the system provide a reference to adjust the structure of the system parameters. And it provides theoretical and technical support for the top level design of the optical target laser active detection system and performance index optimization.

Real-time system for imaging and object detection with a multistatic GPR array

DOEpatents

Paglieroni, David W; Beer, N Reginald; Bond, Steven W; Top, Philip L; Chambers, David H; Mast, Jeffrey E; Donetti, John G; Mason, Blake C; Jones, Steven M

2014-10-07

A method and system for detecting the presence of subsurface objects within a medium is provided. In some embodiments, the imaging and detection system operates in a multistatic mode to collect radar return signals generated by an array of transceiver antenna pairs that is positioned across the surface and that travels down the surface. The imaging and detection system pre-processes the return signal to suppress certain undesirable effects. The imaging and detection system then generates synthetic aperture radar images from real aperture radar images generated from the pre-processed return signal. The imaging and detection system then post-processes the synthetic aperture radar images to improve detection of subsurface objects. The imaging and detection system identifies peaks in the energy levels of the post-processed image frame, which indicates the presence of a subsurface object.

46 CFR 108.405 - Fire detection system.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 46 Shipping 4 2013-10-01 2013-10-01 false Fire detection system. 108.405 Section 108.405 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) A-MOBILE OFFSHORE DRILLING UNITS DESIGN AND EQUIPMENT Fire Extinguishing Systems § 108.405 Fire detection system. (a) Each fire detection system and...

46 CFR 108.405 - Fire detection system.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 4 2011-10-01 2011-10-01 false Fire detection system. 108.405 Section 108.405 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) A-MOBILE OFFSHORE DRILLING UNITS DESIGN AND EQUIPMENT Fire Extinguishing Systems § 108.405 Fire detection system. (a) Each fire detection system and...

46 CFR 108.405 - Fire detection system.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 46 Shipping 4 2014-10-01 2014-10-01 false Fire detection system. 108.405 Section 108.405 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) A-MOBILE OFFSHORE DRILLING UNITS DESIGN AND EQUIPMENT Fire Extinguishing Systems § 108.405 Fire detection system. (a) Each fire detection system and...

46 CFR 108.405 - Fire detection system.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 46 Shipping 4 2012-10-01 2012-10-01 false Fire detection system. 108.405 Section 108.405 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) A-MOBILE OFFSHORE DRILLING UNITS DESIGN AND EQUIPMENT Fire Extinguishing Systems § 108.405 Fire detection system. (a) Each fire detection system and...

46 CFR 161.002-15 - Sample extraction smoke detection systems.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 6 2010-10-01 2010-10-01 false Sample extraction smoke detection systems. 161.002-15..., CONSTRUCTION, AND MATERIALS: SPECIFICATIONS AND APPROVAL ELECTRICAL EQUIPMENT Fire-Protective Systems § 161.002-15 Sample extraction smoke detection systems. The smoke detecting system must consist of a means for...

46 CFR 108.404 - Selection of fire detection system.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 4 2010-10-01 2010-10-01 false Selection of fire detection system. 108.404 Section 108... DESIGN AND EQUIPMENT Fire Extinguishing Systems § 108.404 Selection of fire detection system. (a) If a... space. (b) The fire detection system must be designed to minimize false alarms. ...

A stereo vision-based obstacle detection system in vehicles

NASA Astrophysics Data System (ADS)

Huh, Kunsoo; Park, Jaehak; Hwang, Junyeon; Hong, Daegun

2008-02-01

Obstacle detection is a crucial issue for driver assistance systems as well as for autonomous vehicle guidance function and it has to be performed with high reliability to avoid any potential collision with the front vehicle. The vision-based obstacle detection systems are regarded promising for this purpose because they require little infrastructure on a highway. However, the feasibility of these systems in passenger car requires accurate and robust sensing performance. In this paper, an obstacle detection system using stereo vision sensors is developed. This system utilizes feature matching, epipoplar constraint and feature aggregation in order to robustly detect the initial corresponding pairs. After the initial detection, the system executes the tracking algorithm for the obstacles. The proposed system can detect a front obstacle, a leading vehicle and a vehicle cutting into the lane. Then, the position parameters of the obstacles and leading vehicles can be obtained. The proposed obstacle detection system is implemented on a passenger car and its performance is verified experimentally.

Improvement of the Raman detection system for pesticide residues on/in fruits and vegetables

NASA Astrophysics Data System (ADS)

Li, Yan; Peng, Yankun; Zhai, Chen; Chao, Kuanglin; Qin, Jianwei

2017-05-01

Pesticide residue is one of the major challenges to fruits safety, while the traditional detection methods of pesticide residue on fruits and vegetables can't afford the demand of rapid detection in actual production because of timeconsuming. Thus rapid identification and detection methods for pesticide residue are urgently needed at present. While most Raman detection systems in the market are spot detection systems, which limits the range of application. In the study, our lab develops a Raman detection system to achieve area-scan thorough the self-developed spot detection Raman system with a control software and two devices. In the system, the scanning area is composed of many scanning spots, which means every spot needs to be detected and more time will be taken than area-scan Raman system. But lower detection limit will be achieved in this method. And some detection device is needed towards fruits and vegetables in different shape. Two detection devices are developed to detect spherical fruits and leaf vegetables. During the detection, the device will make spherical fruit rotate along its axis of symmetry, and leaf vegetables will be pressed in the test surface smoothly. The detection probe will be set to keep a proper distance to the surface of fruits and vegetables. It should make sure the laser shins on the surface of spherical fruit vertically. And two software are used to detect spherical fruits and leaf vegetables will be integrated to one, which make the operator easier to switch. Accordingly two detection devices for spherical fruits and leaf vegetables will also be portable devices to make it easier to change. In the study, a new way is developed to achieve area-scan result by spot-scan Raman detection system.

Supporting the Development and Adoption of Automatic Lameness Detection Systems in Dairy Cattle: Effect of System Cost and Performance on Potential Market Shares.

PubMed

Van De Gucht, Tim; Van Weyenberg, Stephanie; Van Nuffel, Annelies; Lauwers, Ludwig; Vangeyte, Jürgen; Saeys, Wouter

2017-10-08

Most automatic lameness detection system prototypes have not yet been commercialized, and are hence not yet adopted in practice. Therefore, the objective of this study was to simulate the effect of detection performance (percentage missed lame cows and percentage false alarms) and system cost on the potential market share of three automatic lameness detection systems relative to visual detection: a system attached to the cow, a walkover system, and a camera system. Simulations were done using a utility model derived from survey responses obtained from dairy farmers in Flanders, Belgium. Overall, systems attached to the cow had the largest market potential, but were still not competitive with visual detection. Increasing the detection performance or lowering the system cost led to higher market shares for automatic systems at the expense of visual detection. The willingness to pay for extra performance was €2.57 per % less missed lame cows, €1.65 per % less false alerts, and €12.7 for lame leg indication, respectively. The presented results could be exploited by system designers to determine the effect of adjustments to the technology on a system's potential adoption rate.

46 CFR 108.409 - Location and spacing of tubing in pneumatic fire detection system.

Code of Federal Regulations, 2010 CFR

2010-10-01

... detection system. 108.409 Section 108.409 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED... and spacing of tubing in pneumatic fire detection system. (a) All tubing in a pneumatic fire detection... exposed in the space. (c) A pneumatic fire detection system must be set to activate after approximately a...

21 CFR 866.5900 - Cystic fibrosis transmembrane conductance regulator (CFTR) gene mutation detection system.

Code of Federal Regulations, 2012 CFR

2012-04-01

... regulator (CFTR) gene mutation detection system. 866.5900 Section 866.5900 Food and Drugs FOOD AND DRUG...) gene mutation detection system. (a) Identification. The CFTR gene mutation detection system is a device used to simultaneously detect and identify a panel of mutations and variants in the CFTR gene. It is...

21 CFR 866.5900 - Cystic fibrosis transmembrane conductance regulator (CFTR) gene mutation detection system.

Code of Federal Regulations, 2013 CFR

2013-04-01

... regulator (CFTR) gene mutation detection system. 866.5900 Section 866.5900 Food and Drugs FOOD AND DRUG...) gene mutation detection system. (a) Identification. The CFTR gene mutation detection system is a device used to simultaneously detect and identify a panel of mutations and variants in the CFTR gene. It is...

21 CFR 866.5900 - Cystic fibrosis transmembrane conductance regulator (CFTR) gene mutation detection system.

Code of Federal Regulations, 2011 CFR

2011-04-01

... regulator (CFTR) gene mutation detection system. 866.5900 Section 866.5900 Food and Drugs FOOD AND DRUG...) gene mutation detection system. (a) Identification. The CFTR gene mutation detection system is a device used to simultaneously detect and identify a panel of mutations and variants in the CFTR gene. It is...

21 CFR 866.5900 - Cystic fibrosis transmembrane conductance regulator (CFTR) gene mutation detection system.

Code of Federal Regulations, 2014 CFR

2014-04-01

... regulator (CFTR) gene mutation detection system. 866.5900 Section 866.5900 Food and Drugs FOOD AND DRUG...) gene mutation detection system. (a) Identification. The CFTR gene mutation detection system is a device used to simultaneously detect and identify a panel of mutations and variants in the CFTR gene. It is...

Buried object detection in GPR images

DOEpatents

Paglieroni, David W; Chambers, David H; Bond, Steven W; Beer, W. Reginald

2014-04-29

A method and system for detecting the presence of subsurface objects within a medium is provided. In some embodiments, the imaging and detection system operates in a multistatic mode to collect radar return signals generated by an array of transceiver antenna pairs that is positioned across the surface and that travels down the surface. The imaging and detection system pre-processes the return signal to suppress certain undesirable effects. The imaging and detection system then generates synthetic aperture radar images from real aperture radar images generated from the pre-processed return signal. The imaging and detection system then post-processes the synthetic aperture radar images to improve detection of subsurface objects. The imaging and detection system identifies peaks in the energy levels of the post-processed image frame, which indicates the presence of a subsurface object.

An automatically tuning intrusion detection system.

PubMed

Yu, Zhenwei; Tsai, Jeffrey J P; Weigert, Thomas

2007-04-01

An intrusion detection system (IDS) is a security layer used to detect ongoing intrusive activities in information systems. Traditionally, intrusion detection relies on extensive knowledge of security experts, in particular, on their familiarity with the computer system to be protected. To reduce this dependence, various data-mining and machine learning techniques have been deployed for intrusion detection. An IDS is usually working in a dynamically changing environment, which forces continuous tuning of the intrusion detection model, in order to maintain sufficient performance. The manual tuning process required by current systems depends on the system operators in working out the tuning solution and in integrating it into the detection model. In this paper, an automatically tuning IDS (ATIDS) is presented. The proposed system will automatically tune the detection model on-the-fly according to the feedback provided by the system operator when false predictions are encountered. The system is evaluated using the KDDCup'99 intrusion detection dataset. Experimental results show that the system achieves up to 35% improvement in terms of misclassification cost when compared with a system lacking the tuning feature. If only 10% false predictions are used to tune the model, the system still achieves about 30% improvement. Moreover, when tuning is not delayed too long, the system can achieve about 20% improvement, with only 1.3% of the false predictions used to tune the model. The results of the experiments show that a practical system can be built based on ATIDS: system operators can focus on verification of predictions with low confidence, as only those predictions determined to be false will be used to tune the detection model.

Integrated Performance Testing Workshop, Modules 6 - 11

DOE Office of Scientific and Technical Information (OSTI.GOV)

Leach, Janice; Torres, Teresa M.

These modules cover performance testing of: Interior Detection Systems; Access Controls; Exterior Detection Systems; Video Assessment Systems; SNM / Contraband Detection Systems; Access Delay Elements

46 CFR 108.407 - Detectors for electric fire detection system.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 4 2010-10-01 2010-10-01 false Detectors for electric fire detection system. 108.407... DRILLING UNITS DESIGN AND EQUIPMENT Fire Extinguishing Systems § 108.407 Detectors for electric fire detection system. (a) Each detector in an electric fire detection system must be located where— (1) No...

Microcontroller based driver alertness detection systems to detect drowsiness

NASA Astrophysics Data System (ADS)

Adenin, Hasibah; Zahari, Rahimi; Lim, Tiong Hoo

2018-04-01

The advancement of embedded system for detecting and preventing drowsiness in a vehicle is a major challenge for road traffic accident systems. To prevent drowsiness while driving, it is necessary to have an alert system that can detect a decline in driver concentration and send a signal to the driver. Studies have shown that traffc accidents usually occur when the driver is distracted while driving. In this paper, we have reviewed a number of detection systems to monitor the concentration of a car driver and propose a portable Driver Alertness Detection System (DADS) to determine the level of concentration of the driver based on pixelated coloration detection technique using facial recognition. A portable camera will be placed at the front visor to capture facial expression and the eye activities. We evaluate DADS using 26 participants and have achieved 100% detection rate with good lighting condition and a low detection rate at night.

Data acquisition system

DOEpatents

Shapiro, Stephen L.; Mani, Sudhindra; Atlas, Eugene L.; Cords, Dieter H. W.; Holbrook, Britt

1997-01-01

A data acquisition circuit for a particle detection system that allows for time tagging of particles detected by the system. The particle detection system screens out background noise and discriminate between hits from scattered and unscattered particles. The detection system can also be adapted to detect a wide variety of particle types. The detection system utilizes a particle detection pixel array, each pixel containing a back-biased PIN diode, and a data acquisition pixel array. Each pixel in the particle detection pixel array is in electrical contact with a pixel in the data acquisition pixel array. In response to a particle hit, the affected PIN diodes generate a current, which is detected by the corresponding data acquisition pixels. This current is integrated to produce a voltage across a capacitor, the voltage being related to the amount of energy deposited in the pixel by the particle. The current is also used to trigger a read of the pixel hit by the particle.

Adaptable radiation monitoring system and method

DOEpatents

Archer, Daniel E [Livermore, CA; Beauchamp, Brock R [San Ramon, CA; Mauger, G Joseph [Livermore, CA; Nelson, Karl E [Livermore, CA; Mercer, Michael B [Manteca, CA; Pletcher, David C [Sacramento, CA; Riot, Vincent J [Berkeley, CA; Schek, James L [Tracy, CA; Knapp, David A [Livermore, CA

2006-06-20

A portable radioactive-material detection system capable of detecting radioactive sources moving at high speeds. The system has at least one radiation detector capable of detecting gamma-radiation and coupled to an MCA capable of collecting spectral data in very small time bins of less than about 150 msec. A computer processor is connected to the MCA for determining from the spectral data if a triggering event has occurred. Spectral data is stored on a data storage device, and a power source supplies power to the detection system. Various configurations of the detection system may be adaptably arranged for various radiation detection scenarios. In a preferred embodiment, the computer processor operates as a server which receives spectral data from other networked detection systems, and communicates the collected data to a central data reporting system.

Minimum detectable gas concentration performance evaluation method for gas leak infrared imaging detection systems.

PubMed

Zhang, Xu; Jin, Weiqi; Li, Jiakun; Wang, Xia; Li, Shuo

2017-04-01

Thermal imaging technology is an effective means of detecting hazardous gas leaks. Much attention has been paid to evaluation of the performance of gas leak infrared imaging detection systems due to several potential applications. The minimum resolvable temperature difference (MRTD) and the minimum detectable temperature difference (MDTD) are commonly used as the main indicators of thermal imaging system performance. This paper establishes a minimum detectable gas concentration (MDGC) performance evaluation model based on the definition and derivation of MDTD. We proposed the direct calculation and equivalent calculation method of MDGC based on the MDTD measurement system. We build an experimental MDGC measurement system, which indicates the MDGC model can describe the detection performance of a thermal imaging system to typical gases. The direct calculation, equivalent calculation, and direct measurement results are consistent. The MDGC and the minimum resolvable gas concentration (MRGC) model can effectively describe the performance of "detection" and "spatial detail resolution" of thermal imaging systems to gas leak, respectively, and constitute the main performance indicators of gas leak detection systems.

40 CFR 63.1184 - What do I need to know about the design specifications, installation, and operation of a bag leak...

Code of Federal Regulations, 2010 CFR

2010-07-01

... design specifications, installation, and operation of a bag leak detection system? 63.1184 Section 63... bag leak detection system? A bag leak detection system must meet the following requirements: (a) The bag leak detection system must be certified by the manufacturer to be capable of detecting PM...

A Survey on Anomaly Based Host Intrusion Detection System

NASA Astrophysics Data System (ADS)

Jose, Shijoe; Malathi, D.; Reddy, Bharath; Jayaseeli, Dorathi

2018-04-01

An intrusion detection system (IDS) is hardware, software or a combination of two, for monitoring network or system activities to detect malicious signs. In computer security, designing a robust intrusion detection system is one of the most fundamental and important problems. The primary function of system is detecting intrusion and gives alerts when user tries to intrusion on timely manner. In these techniques when IDS find out intrusion it will send alert massage to the system administrator. Anomaly detection is an important problem that has been researched within diverse research areas and application domains. This survey tries to provide a structured and comprehensive overview of the research on anomaly detection. From the existing anomaly detection techniques, each technique has relative strengths and weaknesses. The current state of the experiment practice in the field of anomaly-based intrusion detection is reviewed and survey recent studies in this. This survey provides a study of existing anomaly detection techniques, and how the techniques used in one area can be applied in another application domain.

Accurate mobile malware detection and classification in the cloud.

PubMed

Wang, Xiaolei; Yang, Yuexiang; Zeng, Yingzhi

2015-01-01

As the dominator of the Smartphone operating system market, consequently android has attracted the attention of s malware authors and researcher alike. The number of types of android malware is increasing rapidly regardless of the considerable number of proposed malware analysis systems. In this paper, by taking advantages of low false-positive rate of misuse detection and the ability of anomaly detection to detect zero-day malware, we propose a novel hybrid detection system based on a new open-source framework CuckooDroid, which enables the use of Cuckoo Sandbox's features to analyze Android malware through dynamic and static analysis. Our proposed system mainly consists of two parts: anomaly detection engine performing abnormal apps detection through dynamic analysis; signature detection engine performing known malware detection and classification with the combination of static and dynamic analysis. We evaluate our system using 5560 malware samples and 6000 benign samples. Experiments show that our anomaly detection engine with dynamic analysis is capable of detecting zero-day malware with a low false negative rate (1.16 %) and acceptable false positive rate (1.30 %); it is worth noting that our signature detection engine with hybrid analysis can accurately classify malware samples with an average positive rate 98.94 %. Considering the intensive computing resources required by the static and dynamic analysis, our proposed detection system should be deployed off-device, such as in the Cloud. The app store markets and the ordinary users can access our detection system for malware detection through cloud service.

Damage Detection and Verification System (DDVS) for In-Situ Health Monitoring

NASA Technical Reports Server (NTRS)

Williams, Martha K.; Lewis, Mark; Szafran, J.; Shelton, C.; Ludwig, L.; Gibson, T.; Lane, J.; Trautwein, T.

2015-01-01

Project presentation for Game Changing Program Smart Book Release. Detection and Verification System (DDVS) expands the Flat Surface Damage Detection System (FSDDS) sensory panels damage detection capabilities and includes an autonomous inspection capability utilizing cameras and dynamic computer vision algorithms to verify system health. Objectives of this formulation task are to establish the concept of operations, formulate the system requirements for a potential ISS flight experiment, and develop a preliminary design of an autonomous inspection capability system that will be demonstrated as a proof-of-concept ground based damage detection and inspection system.

Integration of the TDWR and LLWAS wind shear detection system

NASA Technical Reports Server (NTRS)

Cornman, Larry

1991-01-01

Operational demonstrations of a prototype TDWR/LLWAS (Terminal Doppler Weather Radar/Low Level Wind shear Alarm System) integrated wind shear detection system were conducted. The integration of wind shear detection systems is needed to provide end-users with a single, consensus source of information. A properly implemented integrated system provides wind shear warnings of a higher quality than stand-alone LLWAS or TDWR systems. The algorithmic concept used to generate the TDWR/LLWAS integrated products and several case studies are discussed, indicating the viability and potential of integrated wind shear detection systems. Implications for integrating ground and airborne wind shear detection systems are briefly examined.

46 CFR 111.05-21 - Ground detection.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 4 2011-10-01 2011-10-01 false Ground detection. 111.05-21 Section 111.05-21 Shipping... REQUIREMENTS Equipment Ground, Ground Detection, and Grounded Systems § 111.05-21 Ground detection. There must be ground detection for each: (a) Electric propulsion system; (b) Ship's service power system; (c...

46 CFR 111.05-21 - Ground detection.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 4 2010-10-01 2010-10-01 false Ground detection. 111.05-21 Section 111.05-21 Shipping... REQUIREMENTS Equipment Ground, Ground Detection, and Grounded Systems § 111.05-21 Ground detection. There must be ground detection for each: (a) Electric propulsion system; (b) Ship's service power system; (c...

76 FR 70075 - Proximity Detection Systems for Continuous Mining Machines in Underground Coal Mines

Federal Register 2010, 2011, 2012, 2013, 2014

2011-11-10

... Detection Systems for Continuous Mining Machines in Underground Coal Mines AGENCY: Mine Safety and Health... proposed rule addressing Proximity Detection Systems for Continuous Mining Machines in Underground Coal... Detection Systems for Continuous Mining Machines in Underground Coal Mines. MSHA conducted hearings on...

76 FR 63238 - Proximity Detection Systems for Continuous Mining Machines in Underground Coal Mines

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-12

... Detection Systems for Continuous Mining Machines in Underground Coal Mines AGENCY: Mine Safety and Health... Agency's proposed rule addressing Proximity Detection Systems for Continuous Mining Machines in... proposed rule for Proximity Detection Systems on Continuous Mining Machines in Underground Coal Mines. Due...

21 CFR 864.7280 - Factor V Leiden DNA mutation detection systems.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Factor V Leiden DNA mutation detection systems....7280 Factor V Leiden DNA mutation detection systems. (a) Identification. Factor V Leiden deoxyribonucleic acid (DNA) mutation detection systems are devices that consist of different reagents and...

21 CFR 864.7280 - Factor V Leiden DNA mutation detection systems.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 21 Food and Drugs 8 2011-04-01 2011-04-01 false Factor V Leiden DNA mutation detection systems....7280 Factor V Leiden DNA mutation detection systems. (a) Identification. Factor V Leiden deoxyribonucleic acid (DNA) mutation detection systems are devices that consist of different reagents and...

21 CFR 864.7280 - Factor V Leiden DNA mutation detection systems.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 21 Food and Drugs 8 2012-04-01 2012-04-01 false Factor V Leiden DNA mutation detection systems....7280 Factor V Leiden DNA mutation detection systems. (a) Identification. Factor V Leiden deoxyribonucleic acid (DNA) mutation detection systems are devices that consist of different reagents and...

21 CFR 864.7280 - Factor V Leiden DNA mutation detection systems.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 21 Food and Drugs 8 2013-04-01 2013-04-01 false Factor V Leiden DNA mutation detection systems....7280 Factor V Leiden DNA mutation detection systems. (a) Identification. Factor V Leiden deoxyribonucleic acid (DNA) mutation detection systems are devices that consist of different reagents and...

21 CFR 864.7280 - Factor V Leiden DNA mutation detection systems.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 21 Food and Drugs 8 2014-04-01 2014-04-01 false Factor V Leiden DNA mutation detection systems....7280 Factor V Leiden DNA mutation detection systems. (a) Identification. Factor V Leiden deoxyribonucleic acid (DNA) mutation detection systems are devices that consist of different reagents and...

Vision-based vehicle detection and tracking algorithm design

NASA Astrophysics Data System (ADS)

Hwang, Junyeon; Huh, Kunsoo; Lee, Donghwi

2009-12-01

The vision-based vehicle detection in front of an ego-vehicle is regarded as promising for driver assistance as well as for autonomous vehicle guidance. The feasibility of vehicle detection in a passenger car requires accurate and robust sensing performance. A multivehicle detection system based on stereo vision has been developed for better accuracy and robustness. This system utilizes morphological filter, feature detector, template matching, and epipolar constraint techniques in order to detect the corresponding pairs of vehicles. After the initial detection, the system executes the tracking algorithm for the vehicles. The proposed system can detect front vehicles such as the leading vehicle and side-lane vehicles. The position parameters of the vehicles located in front are obtained based on the detection information. The proposed vehicle detection system is implemented on a passenger car, and its performance is verified experimentally.

Advanced power system protection and incipient fault detection and protection of spaceborne power systems

NASA Technical Reports Server (NTRS)

Russell, B. Don

1989-01-01

This research concentrated on the application of advanced signal processing, expert system, and digital technologies for the detection and control of low grade, incipient faults on spaceborne power systems. The researchers have considerable experience in the application of advanced digital technologies and the protection of terrestrial power systems. This experience was used in the current contracts to develop new approaches for protecting the electrical distribution system in spaceborne applications. The project was divided into three distinct areas: (1) investigate the applicability of fault detection algorithms developed for terrestrial power systems to the detection of faults in spaceborne systems; (2) investigate the digital hardware and architectures required to monitor and control spaceborne power systems with full capability to implement new detection and diagnostic algorithms; and (3) develop a real-time expert operating system for implementing diagnostic and protection algorithms. Significant progress has been made in each of the above areas. Several terrestrial fault detection algorithms were modified to better adapt to spaceborne power system environments. Several digital architectures were developed and evaluated in light of the fault detection algorithms.

Farmers' preferences for automatic lameness-detection systems in dairy cattle.

PubMed

Van De Gucht, T; Saeys, W; Van Nuffel, A; Pluym, L; Piccart, K; Lauwers, L; Vangeyte, J; Van Weyenberg, S

2017-07-01

As lameness is a major health problem in dairy herds, a lot of attention goes to the development of automated lameness-detection systems. Few systems have made it to the market, as most are currently still in development. To get these systems ready for practice, developers need to define which system characteristics are important for the farmers as end users. In this study, farmers' preferences for the different characteristics of proposed lameness-detection systems were investigated. In addition, the influence of sociodemographic and farm characteristics on farmers' preferences was assessed. The third aim was to find out if preferences change after the farmer receives extra information on lameness and its consequences. Therefore, a discrete choice experiment was designed with 3 alternative lameness-detection systems: a system attached to the cow, a walkover system, and a camera system. Each system was defined by 4 characteristics: the percentage missed lame cows, the percentage false alarms, the system cost, and the ability to indicate which leg is lame. The choice experiment was embedded in an online survey. After answering general questions and choosing their preferred option in 4 choice sets, extra information on lameness was provided. Consecutively, farmers were shown a second block of 4 choice sets. Results from 135 responses showed that farmers' preferences were influenced by the 4 system characteristics. The importance a farmer attaches to lameness, the interval between calving and first insemination, and the presence of an estrus-detection system contributed significantly to the value a farmer attaches to lameness-detection systems. Farmers who already use an estrus detection system were more willing to use automatic detection systems instead of visual lameness detection. Similarly, farmers who achieve shorter intervals between calving and first insemination and farmers who find lameness highly important had a higher tendency to choose for automatic lameness detection. A sensor attached to the cow was preferred, followed by a walkover system and a camera system. In general, visual lameness detection was preferred over automatic detection systems, but this preference changed after informing farmers about the consequences of lameness. To conclude, the system cost and performance were important features, but dairy farmers should be sensitized on the consequences of lameness and its effect on farm profitability. Copyright © 2017 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.

Long distance high power optical laser fiber break detection and continuity monitoring systems and methods

DOEpatents

Rinzler, Charles C.; Gray, William C.; Faircloth, Brian O.; Zediker, Mark S.

2016-02-23

A monitoring and detection system for use on high power laser systems, long distance high power laser systems and tools for performing high power laser operations. In particular, the monitoring and detection systems provide break detection and continuity protection for performing high power laser operations on, and in, remote and difficult to access locations.

Human care system for heart-rate and human-movement trajectory in home and its application to detect mental disease

NASA Astrophysics Data System (ADS)

Hata, Yutaka; Kanazawa, Seigo; Endo, Maki; Tsuchiya, Naoki; Nakajima, Hiroshi

2012-06-01

This paper proposes a heart rate monitoring system for detecting autonomic nervous system by the heart rate variability using an air pressure sensor to diagnose mental disease. Moreover, we propose a human behavior monitoring system for detecting the human trajectory in home by an infrared camera. In day and night times, the human behavior monitoring system detects the human movement in home. The heart rate monitoring system detects the heart rate in bed in night time. The air pressure sensor consists of a rubber tube, cushion cover and pressure sensor, and it detects the heart rate by setting it to bed. It unconstraintly detects the RR-intervals; thereby the autonomic nervous system can be assessed. The autonomic nervous system analysis can examine the mental disease. While, the human behavior monitoring system obtains distance distribution image by an infrared camera. It classifies adult, child and the other object from distance distribution obtained by the camera, and records their trajectories. This behavior, i.e., trajectory in home, strongly corresponds to cognitive disorders. Thus, the total system can detect mental disease and cognitive disorders by uncontacted sensors to human body.

Spot restoration for GPR image post-processing

DOEpatents

Paglieroni, David W; Beer, N. Reginald

2014-05-20

A method and system for detecting the presence of subsurface objects within a medium is provided. In some embodiments, the imaging and detection system operates in a multistatic mode to collect radar return signals generated by an array of transceiver antenna pairs that is positioned across the surface and that travels down the surface. The imaging and detection system pre-processes the return signal to suppress certain undesirable effects. The imaging and detection system then generates synthetic aperture radar images from real aperture radar images generated from the pre-processed return signal. The imaging and detection system then post-processes the synthetic aperture radar images to improve detection of subsurface objects. The imaging and detection system identifies peaks in the energy levels of the post-processed image frame, which indicates the presence of a subsurface object.

Detecting impossible changes in infancy: a three-system account

PubMed Central

Wang, Su-hua; Baillargeon, Renée

2012-01-01

Can infants detect that an object has magically disappeared, broken apart or changed color while briefly hidden? Recent research suggests that infants detect some but not other ‘impossible’ changes; and that various contextual manipulations can induce infants to detect changes they would not otherwise detect. We present an account that includes three systems: a physical-reasoning, an object-tracking, and an object-representation system. What impossible changes infants detect depends on what object information is included in the physical-reasoning system; this information becomes subject to a principle of persistence, which states that objects can undergo no spontaneous or uncaused change. What contextual manipulations induce infants to detect impossible changes depends on complex interplays between the physical-reasoning system and the object-tracking and object-representation systems. PMID:18078778

Bayesian analysis of energy and count rate data for detection of low count rate radioactive sources.

PubMed

Klumpp, John; Brandl, Alexander

2015-03-01

A particle counting and detection system is proposed that searches for elevated count rates in multiple energy regions simultaneously. The system analyzes time-interval data (e.g., time between counts), as this was shown to be a more sensitive technique for detecting low count rate sources compared to analyzing counts per unit interval (Luo et al. 2013). Two distinct versions of the detection system are developed. The first is intended for situations in which the sample is fixed and can be measured for an unlimited amount of time. The second version is intended to detect sources that are physically moving relative to the detector, such as a truck moving past a fixed roadside detector or a waste storage facility under an airplane. In both cases, the detection system is expected to be active indefinitely; i.e., it is an online detection system. Both versions of the multi-energy detection systems are compared to their respective gross count rate detection systems in terms of Type I and Type II error rates and sensitivity.

Framework for evaluating public health surveillance systems for early detection of outbreaks: recommendations from the CDC Working Group.

PubMed

Buehler, James W; Hopkins, Richard S; Overhage, J Marc; Sosin, Daniel M; Tong, Van

2004-05-07

The threat of terrorism and high-profile disease outbreaks has drawn attention to public health surveillance systems for early detection of outbreaks. State and local health departments are enhancing existing surveillance systems and developing new systems to better detect outbreaks through public health surveillance. However, information is limited about the usefulness of surveillance systems for outbreak detection or the best ways to support this function. This report supplements previous guidelines for evaluating public health surveillance systems. Use of this framework is intended to improve decision-making regarding the implementation of surveillance for outbreak detection. Use of a standardized evaluation methodology, including description of system design and operation, also will enhance the exchange of information regarding methods to improve early detection of outbreaks. The framework directs particular attention to the measurement of timeliness and validity for outbreak detection. The evaluation framework is designed to support assessment and description of all surveillance approaches to early detection, whether through traditional disease reporting, specialized analytic routines for aberration detection, or surveillance using early indicators of disease outbreaks, such as syndromic surveillance.

Pothole Detection System Using a Black-box Camera.

PubMed

Jo, Youngtae; Ryu, Seungki

2015-11-19

Aging roads and poor road-maintenance systems result a large number of potholes, whose numbers increase over time. Potholes jeopardize road safety and transportation efficiency. Moreover, they are often a contributing factor to car accidents. To address the problems associated with potholes, the locations and size of potholes must be determined quickly. Sophisticated road-maintenance strategies can be developed using a pothole database, which requires a specific pothole-detection system that can collect pothole information at low cost and over a wide area. However, pothole repair has long relied on manual detection efforts. Recent automatic detection systems, such as those based on vibrations or laser scanning, are insufficient to detect potholes correctly and inexpensively owing to the unstable detection of vibration-based methods and high costs of laser scanning-based methods. Thus, in this paper, we introduce a new pothole-detection system using a commercial black-box camera. The proposed system detects potholes over a wide area and at low cost. We have developed a novel pothole-detection algorithm specifically designed to work with the embedded computing environments of black-box cameras. Experimental results are presented with our proposed system, showing that potholes can be detected accurately in real-time.

Sensitivity Comparison of Vapor Trace Detection of Explosives Based on Chemo-Mechanical Sensing with Optical Detection and Capacitive Sensing with Electronic Detection

PubMed Central

Strle, Drago; Štefane, Bogdan; Zupanič, Erik; Trifkovič, Mario; Maček, Marijan; Jakša, Gregor; Kvasič, Ivan; Muševič, Igor

2014-01-01

The article offers a comparison of the sensitivities for vapour trace detection of Trinitrotoluene (TNT) explosives of two different sensor systems: a chemo-mechanical sensor based on chemically modified Atomic Force Microscope (AFM) cantilevers based on Micro Electro Mechanical System (MEMS) technology with optical detection (CMO), and a miniature system based on capacitive detection of chemically functionalized planar capacitors with interdigitated electrodes with a comb-like structure with electronic detection (CE). In both cases (either CMO or CE), the sensor surfaces are chemically functionalized with a layer of APhS (trimethoxyphenylsilane) molecules, which give the strongest sensor response for TNT. The construction and calibration of a vapour generator is also presented. The measurements of the sensor response to TNT are performed under equal conditions for both systems, and the results show that CE system with ultrasensitive electronics is far superior to optical detection using MEMS. Using CMO system, we can detect 300 molecules of TNT in 10+12 molecules of N2 carrier gas, whereas the CE system can detect three molecules of TNT in 10+12 molecules of carrier N2. PMID:24977388

Simple colonoscopy reporting system checking the detection rate of colon polyps.

PubMed

Kim, Jae Hyun; Choi, Youn Jung; Kwon, Hye Jung; Park, Seun Ja; Park, Moo In; Moon, Won; Kim, Sung Eun

2015-08-21

To present a simple colonoscopy reporting system that can be checked easily the detection rate of colon polyps. A simple colonoscopy reporting system Kosin Gastroenterology (KG quality reporting system) was developed. The polyp detection rate (PDR), adenoma detection rate (ADR), serrated polyp detection rate (SDR), and advanced adenoma detection rate (AADR) are easily calculated to use this system. In our gastroenterology center, the PDR, ADR, SDR, and AADR test results from each gastroenterologist were updated, every month. Between June 2014, when the program was started, and December 2014, the overall PDR and ADR in our center were 62.5% and 41.4%, respectively. And the overall SDR and AADR were 7.5% and 12.1%, respectively. We envision that KG quality reporting system can be applied to develop a comprehensive system to check colon polyp detection rates in other gastroenterology centers.

Evaluation of a near-infrared-type contrast medium extravasation detection system using a swine model.

PubMed

Ishihara, Toshihiro; Kobayashi, Tatsushi; Ikeno, Naoya; Hayashi, Takayuki; Sakakibara, Masahiro; Niki, Noboru; Satake, Mitsuo; Moriyama, Noriyuki

2014-01-01

To refine the development and evaluate the near-infrared (NIR) extravasation detection system and its ability to detect extravasation during a contrast-enhanced computed tomography (CT) examination. The NIR extravasation detection system projects the NIR light through the surface of the human skin then, using its sensory system, will monitor the changes in the amount of NIR that reflected, which varies based on absorption properties.Seven female pigs were used to evaluate the contrast media extravasation detection system, using a 20-gauge intravenous catheter, when injected at a rate of 1 mL/s into 4 different locations just under the skin in the thigh section. Using 3-dimensional CT images, we evaluated the extravasations between time and volume, depth and volume, and finally depth and time to detect. We confirmed that the NIR light, 950-nm wavelength, used by the extravasation detection system is well absorbed by contrast media, making changes easy to detect. The average time to detect an extravasation was 2.05 seconds at a depth of 2.0 mm below the skin with a volume of 1.3 mL, 2.57 seconds at a depth between 2.1 and 5 mm below the skin and a volume of 3.47 mL, 10.5 seconds for depths greater than 5.1 mm and a volume of 11.1 mL. The detection accuracy was significantly deteriorated when the depth exceeded 5.0 mm (Tukey-Kramer, P < 0.05) CONCLUSIONS: The extravasation system detection system that is using NIR has a high level of detection sensitivity. The sensitivity enables the system to detect extravasation at depths less than 2 mm with a volume of 1.5 mL and at depths less than 5 mm with a volume of 3.5 mL. The extravasation detection system could be suitable for use during examinations.

46 CFR 95.05-1 - Fire detecting, manual alarm, and supervised patrol systems.

Code of Federal Regulations, 2014 CFR

2014-10-01

... provided a smoke detecting or other suitable type fire detecting system. (c) Enclosed spaces which are “specially suitable for vehicles” shall be fitted with an approved fire or smoke detecting system. [CGFR 66...

46 CFR 95.05-1 - Fire detecting, manual alarm, and supervised patrol systems.

Code of Federal Regulations, 2013 CFR

2013-10-01

... provided a smoke detecting or other suitable type fire detecting system. (c) Enclosed spaces which are “specially suitable for vehicles” shall be fitted with an approved fire or smoke detecting system. [CGFR 66...

14 CFR 25.858 - Cargo or baggage compartment smoke or fire detection systems.

Code of Federal Regulations, 2010 CFR

2010-01-01

... detection systems. 25.858 Section 25.858 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT... Construction Fire Protection § 25.858 Cargo or baggage compartment smoke or fire detection systems. If... must be met for each cargo or baggage compartment with those provisions: (a) The detection system must...

75 FR 81708 - Notice of Decision To Issue Buy American Waivers for Foreign Object Debris (FOD) Detection Equipment

Federal Register 2010, 2011, 2012, 2013, 2014

2010-12-28

... Circular 150/5220-24, Airport Foreign Object Debris (FOD) detection equipment, detailing system... produce sufficient and reasonable amounts of stationary FOD detection systems; the FAA issued a notice in... manufacturing stationary FOD detection systems in the United States: Trex Aviation Systems and QinetiQ. Although...

46 CFR 161.002-15 - Sample extraction smoke detection systems.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 46 Shipping 6 2014-10-01 2014-10-01 false Sample extraction smoke detection systems. 161.002-15...-15 Sample extraction smoke detection systems. The smoke detecting system must consist of a means for... smoke, together with visual and audible alarms for indicating the presence of smoke. [CGD 94-108, 61 FR...

46 CFR 161.002-15 - Sample extraction smoke detection systems.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 6 2011-10-01 2011-10-01 false Sample extraction smoke detection systems. 161.002-15...-15 Sample extraction smoke detection systems. The smoke detecting system must consist of a means for... smoke, together with visual and audible alarms for indicating the presence of smoke. [CGD 94-108, 61 FR...

46 CFR 161.002-15 - Sample extraction smoke detection systems.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 46 Shipping 6 2012-10-01 2012-10-01 false Sample extraction smoke detection systems. 161.002-15...-15 Sample extraction smoke detection systems. The smoke detecting system must consist of a means for... smoke, together with visual and audible alarms for indicating the presence of smoke. [CGD 94-108, 61 FR...

46 CFR 161.002-15 - Sample extraction smoke detection systems.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 46 Shipping 6 2013-10-01 2013-10-01 false Sample extraction smoke detection systems. 161.002-15...-15 Sample extraction smoke detection systems. The smoke detecting system must consist of a means for... smoke, together with visual and audible alarms for indicating the presence of smoke. [CGD 94-108, 61 FR...

Detection system of capillary array electrophoresis microchip based on optical fiber

NASA Astrophysics Data System (ADS)

Yang, Xiaobo; Bai, Haiming; Yan, Weiping

2009-11-01

To meet the demands of the post-genomic era study and the large parallel detections of epidemic diseases and drug screening, the high throughput micro-fluidic detection system is needed urgently. A scanning laser induced fluorescence detection system based on optical fiber has been established by using a green laser diode double-pumped solid-state laser as excitation source. It includes laser induced fluorescence detection subsystem, capillary array electrophoresis micro-chip, channel identification unit and fluorescent signal processing subsystem. V-shaped detecting probe composed with two optical fibers for transmitting the excitation light and detecting induced fluorescence were constructed. Parallel four-channel signal analysis of capillary electrophoresis was performed on this system by using Rhodamine B as the sample. The distinction of different samples and separation of samples were achieved with the constructed detection system. The lowest detected concentration is 1×10-5 mol/L for Rhodamine B. The results show that the detection system possesses some advantages, such as compact structure, better stability and higher sensitivity, which are beneficial to the development of microminiaturization and integration of capillary array electrophoresis chip.

Underwater electric field detection system based on weakly electric fish

NASA Astrophysics Data System (ADS)

Xue, Wei; Wang, Tianyu; Wang, Qi

2018-04-01

Weakly electric fish sense their surroundings in complete darkness by their active electric field detection system. However, due to the insufficient detection capacity of the electric field, the detection distance is not enough, and the detection accuracy is not high. In this paper, a method of underwater detection based on rotating current field theory is proposed to improve the performance of underwater electric field detection system. First of all, we built underwater detection system based on the theory of the spin current field mathematical model with the help of the results of previous researchers. Then we completed the principle prototype and finished the metal objects in the water environment detection experiments, laid the foundation for the further experiments.

Distributed intrusion detection system based on grid security model

NASA Astrophysics Data System (ADS)

Su, Jie; Liu, Yahui

2008-03-01

Grid computing has developed rapidly with the development of network technology and it can solve the problem of large-scale complex computing by sharing large-scale computing resource. In grid environment, we can realize a distributed and load balance intrusion detection system. This paper first discusses the security mechanism in grid computing and the function of PKI/CA in the grid security system, then gives the application of grid computing character in the distributed intrusion detection system (IDS) based on Artificial Immune System. Finally, it gives a distributed intrusion detection system based on grid security system that can reduce the processing delay and assure the detection rates.

Development of an adaptive failure detection and identification system for detecting aircraft control element failures

NASA Technical Reports Server (NTRS)

Bundick, W. Thomas

1990-01-01

A methodology for designing a failure detection and identification (FDI) system to detect and isolate control element failures in aircraft control systems is reviewed. An FDI system design for a modified B-737 aircraft resulting from this methodology is also reviewed, and the results of evaluating this system via simulation are presented. The FDI system performed well in a no-turbulence environment, but it experienced an unacceptable number of false alarms in atmospheric turbulence. An adaptive FDI system, which adjusts thresholds and other system parameters based on the estimated turbulence level, was developed and evaluated. The adaptive system performed well over all turbulence levels simulated, reliably detecting all but the smallest magnitude partially-missing-surface failures.

Object detection with a multistatic array using singular value decomposition

DOEpatents

Hallquist, Aaron T.; Chambers, David H.

2014-07-01

A method and system for detecting the presence of subsurface objects within a medium is provided. In some embodiments, the detection system operates in a multistatic mode to collect radar return signals generated by an array of transceiver antenna pairs that is positioned across a surface and that travels down the surface. The detection system converts the return signals from a time domain to a frequency domain, resulting in frequency return signals. The detection system then performs a singular value decomposition for each frequency to identify singular values for each frequency. The detection system then detects the presence of a subsurface object based on a comparison of the identified singular values to expected singular values when no subsurface object is present.

Radar signal pre-processing to suppress surface bounce and multipath

DOEpatents

Paglieroni, David W; Mast, Jeffrey E; Beer, N. Reginald

2013-12-31

A method and system for detecting the presence of subsurface objects within a medium is provided. In some embodiments, the imaging and detection system operates in a multistatic mode to collect radar return signals generated by an array of transceiver antenna pairs that is positioned across the surface and that travels down the surface. The imaging and detection system pre-processes that return signal to suppress certain undesirable effects. The imaging and detection system then generates synthetic aperture radar images from real aperture radar images generated from the pre-processed return signal. The imaging and detection system then post-processes the synthetic aperture radar images to improve detection of subsurface objects. The imaging and detection system identifies peaks in the energy levels of the post-processed image frame, which indicates the presence of a subsurface object.

Spatially assisted down-track median filter for GPR image post-processing

DOEpatents

Paglieroni, David W; Beer, N Reginald

2014-10-07

A method and system for detecting the presence of subsurface objects within a medium is provided. In some embodiments, the imaging and detection system operates in a multistatic mode to collect radar return signals generated by an array of transceiver antenna pairs that is positioned across the surface and that travels down the surface. The imaging and detection system pre-processes the return signal to suppress certain undesirable effects. The imaging and detection system then generates synthetic aperture radar images from real aperture radar images generated from the pre-processed return signal. The imaging and detection system then post-processes the synthetic aperture radar images to improve detection of subsurface objects. The imaging and detection system identifies peaks in the energy levels of the post-processed image frame, which indicates the presence of a subsurface object.

Spatially adaptive migration tomography for multistatic GPR imaging

DOEpatents

Paglieroni, David W; Beer, N. Reginald

2013-08-13

A method and system for detecting the presence of subsurface objects within a medium is provided. In some embodiments, the imaging and detection system operates in a multistatic mode to collect radar return signals generated by an array of transceiver antenna pairs that is positioned across the surface and that travels down the surface. The imaging and detection system pre-processes the return signal to suppress certain undesirable effects. The imaging and detection system then generates synthetic aperture radar images from real aperture radar images generated from the pre-processed return signal. The imaging and detection system then post-processes the synthetic aperture radar images to improve detection of subsurface objects. The imaging and detection system identifies peaks in the energy levels of the post-processed image frame, which indicates the presence of a subsurface object.

a Mini Multi-Gas Detection System Based on Infrared Principle

NASA Astrophysics Data System (ADS)

Zhijian, Xie; Qiulin, Tan

2006-12-01

To counter the problems of gas accidents in coal mines, family safety resulted from using gas, a new infrared detection system with integration and miniaturization has been developed. The infrared detection optics principle used in developing this system is mainly analyzed. The idea that multi gas detection is introduced and guided through analyzing single gas detection is got across. Through researching the design of cell structure, the cell with integration and miniaturization has been devised. The way of data transmission on Controller Area Network (CAN) bus is explained. By taking Single-Chip Microcomputer (SCM) as intelligence handling, the functional block diagram of gas detection system is designed with its hardware and software system analyzed and devised. This system designed has reached the technology requirement of lower power consumption, mini-volume, big measure range, and able to realize multi-gas detection.

Synthetic aperture integration (SAI) algorithm for SAR imaging

DOEpatents

Chambers, David H; Mast, Jeffrey E; Paglieroni, David W; Beer, N. Reginald

2013-07-09

A method and system for detecting the presence of subsurface objects within a medium is provided. In some embodiments, the imaging and detection system operates in a multistatic mode to collect radar return signals generated by an array of transceiver antenna pairs that is positioned across the surface and that travels down the surface. The imaging and detection system pre-processes the return signal to suppress certain undesirable effects. The imaging and detection system then generates synthetic aperture radar images from real aperture radar images generated from the pre-processed return signal. The imaging and detection system then post-processes the synthetic aperture radar images to improve detection of subsurface objects. The imaging and detection system identifies peaks in the energy levels of the post-processed image frame, which indicates the presence of a subsurface object.

Zero source insertion technique to account for undersampling in GPR imaging

DOEpatents

Chambers, David H; Mast, Jeffrey E; Paglieroni, David W

2014-02-25

A method and system for detecting the presence of subsurface objects within a medium is provided. In some embodiments, the imaging and detection system operates in a multistatic mode to collect radar return signals generated by an array of transceiver antenna pairs that is positioned across the surface and that travels down the surface. The imaging and detection system pre-processes the return signal to suppress certain undesirable effects. The imaging and detection system then generates synthetic aperture radar images from real aperture radar images generated from the pre-processed return signal. The imaging and detection system then post-processes the synthetic aperture radar images to improve detection of subsurface objects. The imaging and detection system identifies peaks in the energy levels of the post-processed image frame, which indicates the presence of a subsurface object.

Portable modular detection system

DOEpatents

Brennan, James S [Rodeo, CA; Singh, Anup [Danville, CA; Throckmorton, Daniel J [Tracy, CA; Stamps, James F [Livermore, CA

2009-10-13

Disclosed herein are portable and modular detection devices and systems for detecting electromagnetic radiation, such as fluorescence, from an analyte which comprises at least one optical element removably attached to at least one alignment rail. Also disclosed are modular detection devices and systems having an integrated lock-in amplifier and spatial filter and assay methods using the portable and modular detection devices.

Evaluation of 3M molecular detection system and ANSR pathogen detection system for rapid detection of salmonella from egg products

USDA-ARS?s Scientific Manuscript database

Loop-mediated isothermal amplification (LAMP) is a novel simple detection technology that amplifies DNA with high speed, efficiency, and specificity under isothermal conditions. The objective of this study was to evaluate the effectiveness of 3M Molecular Detection System (MDS) and ANSR Pathogen Det...

40 CFR 62.14690 - What monitoring equipment must I install and what parameters must I monitor?

Code of Federal Regulations, 2010 CFR

2010-07-01

... subpart, you must install, calibrate, maintain, and continuously operate a bag leak detection system as... detection system for each exhaust stack of the fabric filter. (2) Each bag leak detection system must be... specifications and recommendations. (3) The bag leak detection system must be certified by the manufacturer to be...

40 CFR 63.11553 - What are my notification, reporting, and recordkeeping requirements?

Code of Federal Regulations, 2010 CFR

2010-07-01

... operator that installs bag leak detection systems: “This facility has installed a bag leak detection system in accordance with § 63.11552(b)(3) or (c), has prepared a bag leak detection system monitoring plan in accordance with § 63.11552(c), and will operate each bag leak detection system according to the...

Detection of contamination of municipal water distribution systems

DOEpatents

Cooper, John F [Oakland, CA

2012-01-17

A system for the detection of contaminates of a fluid in a conduit. The conduit is part of a fluid distribution system. A chemical or biological sensor array is connected to the conduit. The sensor array produces an acoustic signal burst in the fluid upon detection of contaminates in the fluid. A supervisory control system connected to the fluid and operatively connected to the fluid distribution system signals the fluid distribution system upon detection of contaminates in the fluid.

Fluorescence detection system for microfluidic droplets

NASA Astrophysics Data System (ADS)

Chen, Binyu; Han, Xiaoming; Su, Zhen; Liu, Quanjun

2018-05-01

In microfluidic detection technology, because of the universality of optical methods in laboratory, optical detection is an attractive solution for microfluidic chip laboratory equipment. In addition, the equipment with high stability and low cost can be realized by integrating appropriate optical detection technology on the chip. This paper reports a detection system for microfluidic droplets. Photomultiplier tubes (PMT) is used as a detection device to improve the sensitivity of detection. This system improves the signal to noise ratio by software filtering and spatial filter. The fluorescence intensity is proportional to the concentration of the fluorescence and intensity of the laser. The fluorescence micro droplets of different concentrations can be distinguished by this system.

Development of Abnormality Detection System for Bathers using Ultrasonic Sensors

NASA Astrophysics Data System (ADS)

Ohnishi, Yosuke; Abe, Takehiko; Nambo, Hidetaka; Kimura, Haruhiko; Ogoshi, Yasuhiro

This paper proposes an abnormality detection system for bather sitting in bathtub. Increasing number of in-bathtub drowning accidents in Japan draws attention. Behind this large number of bathing accidents, Japan's unique social and cultural background come surface. For majority of people in Japan, bathing serves purpose in deep warming up of body, relax and enjoyable time. Therefore it is the custom for the Japanese to soak in bathtub. However overexposure to hot water may cause dizziness or fainting, which is possible to cause in-bathtub drowning. For drowning prevention, the system detects bather's abnormal state using an ultrasonic sensor array. The array, which has many ultrasonic sensors, is installed on the ceiling of bathroom above bathtub. The abnormality detection system uses the following two methods: posture detection and behavior detection. The function of posture detection is to estimate the risk of drowning by monitoring bather's posture. Meanwhile, the function of behavior detection is to estimate the risk of drowning by monitoring bather's behavior. By using these methods, the system detects bathers' different state from normal. As a result of experiment with a subject in the bathtub, the system was possible to detect abnormal state using subject's posture and behavior. Therefore the system is useful for monitoring bather to prevent drowning in bathtub.

An immuno-biosensor system based on quartz crystal microbalance for avian influenza virus detection

NASA Astrophysics Data System (ADS)

Liu, Shengping; Chen, Guoming; Zhou, Qi; Wei, Yunlong

2007-12-01

For the quick detection of Avian Influenza Virus (AIV), a biosensor based on Quartz Crystal Microbalance (QCM) was fabricated according to the specific bonding principle between antibody and antigen. Staphylococcal Protein A (SPA) was extracted from Staphylococcus and purified. Then SPA was coated on the surface of QCM for immobilizing AIV monoclonal antibodies. The use of AIV monoclonal antibody could enhance the specificity of the immuno-biosensor. A multi-channel piezoelectricity detection system for the immuno-biosensor was developed. The system can work for the quick detection of AIV antigen in the case of the entirely aqueous status owe to one special oscillating circuit designed in this work. The optimum conditions of SPA coating and AIV monoclonal antibody immobilization were investigated utilizing the multi-channel detection system. The preliminary application of the immuno-biosensor system for detection of AIV was evaluated. Results indicate that the immuno-biosensor system can detect the AIV antigens with a linear range of 3-200ng/ml. The system can accomplish the detection of AIV antigens around 40 minutes.

An Advanced Platform for Biomolecular Detection and Analysis Systems

DTIC Science & Technology

2005-02-01

AFRL-IF-RS-TR-2005-54 Final Technical Report February 2005 AN ADVANCED PLATFORM FOR BIOMOLECULAR DETECTION AND ANALYSIS SYSTEMS...SUBTITLE AN ADVANCED PLATFORM FOR BIOMOLECULAR DETECTION AND ANALYSIS SYSTEMS 6. AUTHOR(S) David J. Beebe 5. FUNDING NUMBERS G...detection, analysis and response as well as many non BC warfare applications such as environmental toxicology, clinical detection and diagnosis

The combination design for open and endoscopic surgery using fluorescence molecular imaging technology

NASA Astrophysics Data System (ADS)

Mao, Yamin; Jiang, Shixin; Ye, Jinzuo; An, Yu; Yang, Xin; Chi, Chongwei; Tian, Jie

2015-03-01

For clinical surgery, it is still a challenge to objectively determine tumor margins during surgery. With the development of medical imaging technology, fluorescence molecular imaging (FMI) method can provide real-time intraoperative tumor margin information. Furthermore, surgical navigation system based on FMI technology plays an important role for the aid of surgeons' precise tumor margin decision. However, detection depth is the most limitation exists in the FMI technique and the method convenient for either macro superficial detection or micro deep tissue detection is needed. In this study, we combined advantages of both open surgery and endoscopic imaging systems with FMI technology. Indocyanine green (ICG) experiments were performed to confirm the feasibility of fluorescence detection in our system. Then, the ICG signal was photographed in the detection area with our system. When the system connected with endoscope lens, the minimum quantity of ICG detected by our system was 0.195 ug. For aspect of C mount lens, the sensitivity of ICG detection with our system was 0.195ug. Our experiments results proved that it was feasible to detect fluorescence images with this combination method. Our system shows great potential in the clinical applications of precise dissection of various tumors

Systems and Methods for Automated Water Detection Using Visible Sensors

NASA Technical Reports Server (NTRS)

Rankin, Arturo L. (Inventor); Matthies, Larry H. (Inventor); Bellutta, Paolo (Inventor)

2016-01-01

Systems and methods are disclosed that include automated machine vision that can utilize images of scenes captured by a 3D imaging system configured to image light within the visible light spectrum to detect water. One embodiment includes autonomously detecting water bodies within a scene including capturing at least one 3D image of a scene using a sensor system configured to detect visible light and to measure distance from points within the scene to the sensor system, and detecting water within the scene using a processor configured to detect regions within each of the at least one 3D images that possess at least one characteristic indicative of the presence of water.

Early distinction system of mine fire in underground by using a neural-network system

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ohga, Kotaro; Higuchi, Kiyoshi

1996-12-31

In our laboratory, a new detection system using smell detectors was developed to detect the spontaneous combustion of coal and the combustion of other materials used underground. The results of experiments clearly the combustion of materials can be detected earlier by this detection system than by conventional detectors for gas and smoke, and there were significant differences between output data from each smell detector for coal, rubber, oil and wood. In order to discern the source of combustion gases, we have been developing a distinction system using a neural-network system. It has shown successful results in laboratory tests. This papermore » describes our detection system using smell detectors and our distinction system which uses a neural-network system, and presents results of experiments using both systems.« less

Laser-induced photo emission detection: data acquisition based on light intensity counting

NASA Astrophysics Data System (ADS)

Yulianto, N.; Yudasari, N.; Putri, K. Y.

2017-04-01

Laser Induced Breakdown Detection (LIBD) is one of the quantification techniques for colloids. There are two ways of detection in LIBD: optical detection and acoustic detection. LIBD is based on the detection of plasma emission due to the interaction between particle and laser beam. In this research, the changing of light intensity during plasma formations was detected by a photodiode sensor. A photo emission data acquisition system was built to collect and transform them into digital counts. The real-time system used data acquisition device National Instrument DAQ 6009 and LABVIEW software. The system has been tested on distilled water and tap water samples. The result showed 99.8% accuracy by using counting technique in comparison to the acoustic detection with sample rate of 10 Hz, thus the acquisition system can be applied as an alternative method to the existing LIBD acquisition system.

Confabulation Based Real-time Anomaly Detection for Wide-area Surveillance Using Heterogeneous High Performance Computing Architecture

DTIC Science & Technology

2015-06-01

system accuracy. The AnRAD system was also generalized for the additional application of network intrusion detection . A self-structuring technique...to Host- based Intrusion Detection Systems using Contiguous and Discontiguous System Call Patterns,” IEEE Transactions on Computer, 63(4), pp. 807...square kilometer areas. The anomaly recognition and detection (AnRAD) system was built as a cogent confabulation network . It represented road

Interference and deception detection technology of satellite navigation based on deep learning

NASA Astrophysics Data System (ADS)

Chen, Weiyi; Deng, Pingke; Qu, Yi; Zhang, Xiaoguang; Li, Yaping

2017-10-01

Satellite navigation system plays an important role in people's daily life and war. The strategic position of satellite navigation system is prominent, so it is very important to ensure that the satellite navigation system is not disturbed or destroyed. It is a critical means to detect the jamming signal to avoid the accident in a navigation system. At present, the detection technology of jamming signal in satellite navigation system is not intelligent , mainly relying on artificial decision and experience. For this issue, the paper proposes a method based on deep learning to monitor the interference source in a satellite navigation. By training the interference signal data, and extracting the features of the interference signal, the detection sys tem model is constructed. The simulation results show that, the detection accuracy of our detection system can reach nearly 70%. The method in our paper provides a new idea for the research on intelligent detection of interference and deception signal in a satellite navigation system.

Evaluation of video detection systems, volume 2 : effects of illumination conditions in the performance of video detection systems.

DOT National Transportation Integrated Search

2009-05-01

The evaluation of three Video Detection Systems (VDS) at an instrumented signalized intersection in Rantoul : Illinois, at both stop bar and advance detection zones, was performed under a wide range of lighting and : weather conditions. The evaluated...

A feasibility study of stateful automaton packet inspection for streaming application detection systems

NASA Astrophysics Data System (ADS)

Tseng, Kuo-Kun; Lo, Jiao; Liu, Yiming; Chang, Shih-Hao; Merabti, Madjid; Ng, Felix, C. K.; Wu, C. H.

2017-10-01

The rapid development of the internet has brought huge benefits and social impacts; however, internet security has also become a great problem for users, since traditional approaches to packet classification cannot achieve satisfactory detection performance due to their low accuracy and efficiency. In this paper, a new stateful packet inspection method is introduced, which can be embedded in the network gateway and used by a streaming application detection system. This new detection method leverages the inexact automaton approach, using part of the header field and part of the application layer data of a packet. Based on this approach, an advanced detection system is proposed for streaming applications. The workflow of the system involves two stages: the training stage and the detection stage. In the training stage, the system initially captures characteristic patterns from a set of application packet flows. After this training is completed, the detection stage allows the user to detect the target application by capturing new application flows. This new detection approach is also evaluated using experimental analysis; the results of this analysis show that this new approach not only simplifies the management of the state detection system, but also improves the accuracy of data flow detection, making it feasible for real-world network applications.

An FPGA-Based Rapid Wheezing Detection System

PubMed Central

Lin, Bor-Shing; Yen, Tian-Shiue

2014-01-01

Wheezing is often treated as a crucial indicator in the diagnosis of obstructive pulmonary diseases. A rapid wheezing detection system may help physicians to monitor patients over the long-term. In this study, a portable wheezing detection system based on a field-programmable gate array (FPGA) is proposed. This system accelerates wheezing detection, and can be used as either a single-process system, or as an integrated part of another biomedical signal detection system. The system segments sound signals into 2-second units. A short-time Fourier transform was used to determine the relationship between the time and frequency components of wheezing sound data. A spectrogram was processed using 2D bilateral filtering, edge detection, multithreshold image segmentation, morphological image processing, and image labeling, to extract wheezing features according to computerized respiratory sound analysis (CORSA) standards. These features were then used to train the support vector machine (SVM) and build the classification models. The trained model was used to analyze sound data to detect wheezing. The system runs on a Xilinx Virtex-6 FPGA ML605 platform. The experimental results revealed that the system offered excellent wheezing recognition performance (0.912). The detection process can be used with a clock frequency of 51.97 MHz, and is able to perform rapid wheezing classification. PMID:24481034

Development of a computer-aided detection system for lung cancer diagnosis

NASA Astrophysics Data System (ADS)

Suzuki, Hideo; Inaoka, Noriko; Takabatake, Hirotsugu; Mori, Masaki; Sasaoka, Soichi; Natori, Hiroshi; Suzuki, Akira

1992-06-01

This paper describes a modified system for automatic detection of lung nodules by means of chest x ray image processing techniques. The objective of the system is to help radiologists to improve their accuracy in cancer detection. It is known from retrospective studies of chest x- ray images that radiologists fail to detect about 30 percent of lung cancer cases. A computerized method for detecting lung nodules would be very useful for decreasing the proportion of such oversights. Our proposed system consists of five sub-systems, for image input, lung region determination, nodule detection, rule-based false-positive elimination, and statistical false-positive elimination. In an experiment with the modified system, using 30 lung cancer cases and 78 normal control cases, we obtained figures of 73.3 percent and 89.7 percent for the sensitivity and specificity of the system, respectively. The system has been developed to run on the IBM* PS/55* and IBM RISC System/6000* (RS/6000), and we give the processing time for each platform.

Evaluation of BACTEC 9240 blood culture system by using high-volume aerobic resin media.

PubMed Central

Schwabe, L D; Thomson, R B; Flint, K K; Koontz, F P

1995-01-01

The BACTEC 9240 blood culture system (Becton Dickinson Diagnostic Instrument Systems, Sparks, Md.) is one of three automated, continuous-monitoring systems that is widely used in clinical laboratories. The BACTEC 9240 was compared with the BACTEC NR 660 for the detection of organisms and bacteremic episodes; time to detection of positive cultures; number of false-positive and false-negative cultures; and time needed to load, process, and perform quality control functions by using high-volume aerobic media. Blood specimens (5,282) were inoculated in equal volumes (5 to 10 ml per bottle) into BACTEC Plus Aerobic/F (9240 system) and BACTEC Plus NR26 (660 system) bottles. Clinically significant isolates were detected in 6.6% of cultures, representing 348 microorganisms and 216 bacteremic episodes. Two hundred forty-eight microorganisms were detected by both systems, 48 by the 9240 only and 52 by the 660 only (P = not significant). Of the bacteremic episodes, 158 were detected by both systems, 27 by the 9240 only and 31 by the 660 only (P = not significant). Analysis of data by month revealed equivalent recovery rates for both systems, with the exception of a 30-day period at one study site during which the 660 system detected significantly more microorganisms. Following a proprietary hardware design retrofit of the 9240 instrument, detection rates were again equivalent for the remaining three months at this study site. Positive cultures detected by both systems were detected an average of 4.3 h faster by the 9240 system (21 versus 25.3 h). The numbers of false-positive cultures for the 9240 and 660 systems were 40 (1.0%) and 9 ( < 1.0%), respectively.(ABSTRACT TRUNCATED AT 250 WORDS) PMID:7494044

Research on IPv6 intrusion detection system Snort-based

NASA Astrophysics Data System (ADS)

Shen, Zihao; Wang, Hui

2010-07-01

This paper introduces the common intrusion detection technologies, discusses the work flow of Snort intrusion detection system, and analyzes IPv6 data packet encapsulation and protocol decoding technology. We propose the expanding Snort architecture to support IPv6 intrusion detection in accordance with CIDF standard combined with protocol analysis technology and pattern matching technology, and present its composition. The research indicates that the expanding Snort system can effectively detect various intrusion attacks; it is high in detection efficiency and detection accuracy and reduces false alarm and omission report, which effectively solves the problem of IPv6 intrusion detection.

Multi-Dimensional Damage Detection for Surfaces and Structures

NASA Technical Reports Server (NTRS)

Williams, Martha; Lewis, Mark; Roberson, Luke; Medelius, Pedro; Gibson, Tracy; Parks, Steen; Snyder, Sarah

2013-01-01

Current designs for inflatable or semi-rigidized structures for habitats and space applications use a multiple-layer construction, alternating thin layers with thicker, stronger layers, which produces a layered composite structure that is much better at resisting damage. Even though such composite structures or layered systems are robust, they can still be susceptible to penetration damage. The ability to detect damage to surfaces of inflatable or semi-rigid habitat structures is of great interest to NASA. Damage caused by impacts of foreign objects such as micrometeorites can rupture the shell of these structures, causing loss of critical hardware and/or the life of the crew. While not all impacts will have a catastrophic result, it will be very important to identify and locate areas of the exterior shell that have been damaged by impacts so that repairs (or other provisions) can be made to reduce the probability of shell wall rupture. This disclosure describes a system that will provide real-time data regarding the health of the inflatable shell or rigidized structures, and information related to the location and depth of impact damage. The innovation described here is a method of determining the size, location, and direction of damage in a multilayered structure. In the multi-dimensional damage detection system, layers of two-dimensional thin film detection layers are used to form a layered composite, with non-detection layers separating the detection layers. The non-detection layers may be either thicker or thinner than the detection layers. The thin-film damage detection layers are thin films of materials with a conductive grid or striped pattern. The conductive pattern may be applied by several methods, including printing, plating, sputtering, photolithography, and etching, and can include as many detection layers that are necessary for the structure construction or to afford the detection detail level required. The damage is detected using a detector or sensory system, which may include a time domain reflectometer, resistivity monitoring hardware, or other resistance-based systems. To begin, a layered composite consisting of thin-film damage detection layers separated by non-damage detection layers is fabricated. The damage detection layers are attached to a detector that provides details regarding the physical health of each detection layer individually. If damage occurs to any of the detection layers, a change in the electrical properties of the detection layers damaged occurs, and a response is generated. Real-time analysis of these responses will provide details regarding the depth, location, and size estimation of the damage. Multiple damages can be detected, and the extent (depth) of the damage can be used to generate prognostic information related to the expected lifetime of the layered composite system. The detection system can be fabricated very easily using off-the-shelf equipment, and the detection algorithms can be written and updated (as needed) to provide the level of detail needed based on the system being monitored. Connecting to the thin film detection layers is very easy as well. The truly unique feature of the system is its flexibility; the system can be designed to gather as much (or as little) information as the end user feels necessary. Individual detection layers can be turned on or off as necessary, and algorithms can be used to optimize performance. The system can be used to generate both diagnostic and prognostic information related to the health of layer composite structures, which will be essential if such systems are utilized for space exploration. The technology is also applicable to other in-situ health monitoring systems for structure integrity.

Aircraft IR/acoustic detection evaluation. Volume 2: Development of a ground-based acoustic sensor system for the detection of subsonic jet-powered aircraft

NASA Technical Reports Server (NTRS)

Kraft, Robert E.

1992-01-01

The design and performance of a ground-based acoustic sensor system for the detection of subsonic jet-powered aircraft is described and specified. The acoustic detection system performance criteria will subsequently be used to determine target detection ranges for the subject contract. Although the defined system has never been built and demonstrated in the field, the design parameters were chosen on the basis of achievable technology and overall system practicality. Areas where additional information is needed to substantiate the design are identified.

49 CFR 1544.213 - Use of explosives detection systems.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 9 2011-10-01 2011-10-01 false Use of explosives detection systems. 1544.213...: AIR CARRIERS AND COMMERCIAL OPERATORS Operations § 1544.213 Use of explosives detection systems. (a) Use of explosive detection equipment. If TSA so requires by an amendment to an aircraft operator's...

49 CFR 1544.213 - Use of explosives detection systems.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 49 Transportation 9 2014-10-01 2014-10-01 false Use of explosives detection systems. 1544.213...: AIR CARRIERS AND COMMERCIAL OPERATORS Operations § 1544.213 Use of explosives detection systems. (a) Use of explosive detection equipment. If TSA so requires by an amendment to an aircraft operator's...

49 CFR 1544.213 - Use of explosives detection systems.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 49 Transportation 9 2013-10-01 2013-10-01 false Use of explosives detection systems. 1544.213...: AIR CARRIERS AND COMMERCIAL OPERATORS Operations § 1544.213 Use of explosives detection systems. (a) Use of explosive detection equipment. If TSA so requires by an amendment to an aircraft operator's...

49 CFR 1544.213 - Use of explosives detection systems.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 49 Transportation 9 2012-10-01 2012-10-01 false Use of explosives detection systems. 1544.213...: AIR CARRIERS AND COMMERCIAL OPERATORS Operations § 1544.213 Use of explosives detection systems. (a) Use of explosive detection equipment. If TSA so requires by an amendment to an aircraft operator's...

46 CFR 161.002-9 - Automatic fire detecting system, power supply.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 6 2011-10-01 2011-10-01 false Automatic fire detecting system, power supply. 161.002-9 Section 161.002-9 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) EQUIPMENT...-9 Automatic fire detecting system, power supply. The power supply for an automatic fire detecting...

46 CFR 161.002-9 - Automatic fire detecting system, power supply.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 6 2010-10-01 2010-10-01 false Automatic fire detecting system, power supply. 161.002-9 Section 161.002-9 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) EQUIPMENT...-9 Automatic fire detecting system, power supply. The power supply for an automatic fire detecting...

Estimation and detection information trade-off for x-ray system optimization

NASA Astrophysics Data System (ADS)

Cushing, Johnathan B.; Clarkson, Eric W.; Mandava, Sagar; Bilgin, Ali

2016-05-01

X-ray Computed Tomography (CT) systems perform complex imaging tasks to detect and estimate system parameters, such as a baggage imaging system performing threat detection and generating reconstructions. This leads to a desire to optimize both the detection and estimation performance of a system, but most metrics only focus on one of these aspects. When making design choices there is a need for a concise metric which considers both detection and estimation information parameters, and then provides the user with the collection of possible optimal outcomes. In this paper a graphical analysis of Estimation and Detection Information Trade-off (EDIT) will be explored. EDIT produces curves which allow for a decision to be made for system optimization based on design constraints and costs associated with estimation and detection. EDIT analyzes the system in the estimation information and detection information space where the user is free to pick their own method of calculating these measures. The user of EDIT can choose any desired figure of merit for detection information and estimation information then the EDIT curves will provide the collection of optimal outcomes. The paper will first look at two methods of creating EDIT curves. These curves can be calculated using a wide variety of systems and finding the optimal system by maximizing a figure of merit. EDIT could also be found as an upper bound of the information from a collection of system. These two methods allow for the user to choose a method of calculation which best fits the constraints of their actual system.

Neural Detection of Malicious Network Activities Using a New Direct Parsing and Feature Extraction Technique

DTIC Science & Technology

2015-09-01

intrusion detection systems , neural networks 15. NUMBER OF PAGES 75 16. PRICE CODE 17. SECURITY CLASSIFICATION OF... detection system (IDS) software, which learns to detect and classify network attacks and intrusions through prior training data. With the added criteria of...BACKGROUND The growing threat of malicious network activities and intrusion attempts makes intrusion detection systems (IDS) a

33 CFR 149.421 - What is the requirement for a previously approved fire detection and alarm system on a deepwater...

Code of Federal Regulations, 2010 CFR

2010-07-01

... previously approved fire detection and alarm system on a deepwater port? 149.421 Section 149.421 Navigation... Requirements § 149.421 What is the requirement for a previously approved fire detection and alarm system on a deepwater port? An existing fire detection and alarm system on a deepwater port need not meet the...

33 CFR 149.421 - What is the requirement for a previously approved fire detection and alarm system on a deepwater...

Code of Federal Regulations, 2011 CFR

2011-07-01

... previously approved fire detection and alarm system on a deepwater port? 149.421 Section 149.421 Navigation... Requirements § 149.421 What is the requirement for a previously approved fire detection and alarm system on a deepwater port? An existing fire detection and alarm system on a deepwater port need not meet the...

33 CFR 149.421 - What is the requirement for a previously approved fire detection and alarm system on a deepwater...

Code of Federal Regulations, 2014 CFR

2014-07-01

... previously approved fire detection and alarm system on a deepwater port? 149.421 Section 149.421 Navigation... Requirements § 149.421 What is the requirement for a previously approved fire detection and alarm system on a deepwater port? An existing fire detection and alarm system on a deepwater port need not meet the...

33 CFR 149.421 - What is the requirement for a previously approved fire detection and alarm system on a deepwater...

Code of Federal Regulations, 2012 CFR

2012-07-01

... previously approved fire detection and alarm system on a deepwater port? 149.421 Section 149.421 Navigation... Requirements § 149.421 What is the requirement for a previously approved fire detection and alarm system on a deepwater port? An existing fire detection and alarm system on a deepwater port need not meet the...

33 CFR 149.421 - What is the requirement for a previously approved fire detection and alarm system on a deepwater...

Code of Federal Regulations, 2013 CFR

2013-07-01

... previously approved fire detection and alarm system on a deepwater port? 149.421 Section 149.421 Navigation... Requirements § 149.421 What is the requirement for a previously approved fire detection and alarm system on a deepwater port? An existing fire detection and alarm system on a deepwater port need not meet the...

Intelligent agent-based intrusion detection system using enhanced multiclass SVM.

PubMed

Ganapathy, S; Yogesh, P; Kannan, A

2012-01-01

Intrusion detection systems were used in the past along with various techniques to detect intrusions in networks effectively. However, most of these systems are able to detect the intruders only with high false alarm rate. In this paper, we propose a new intelligent agent-based intrusion detection model for mobile ad hoc networks using a combination of attribute selection, outlier detection, and enhanced multiclass SVM classification methods. For this purpose, an effective preprocessing technique is proposed that improves the detection accuracy and reduces the processing time. Moreover, two new algorithms, namely, an Intelligent Agent Weighted Distance Outlier Detection algorithm and an Intelligent Agent-based Enhanced Multiclass Support Vector Machine algorithm are proposed for detecting the intruders in a distributed database environment that uses intelligent agents for trust management and coordination in transaction processing. The experimental results of the proposed model show that this system detects anomalies with low false alarm rate and high-detection rate when tested with KDD Cup 99 data set.

Intelligent Agent-Based Intrusion Detection System Using Enhanced Multiclass SVM

PubMed Central

Ganapathy, S.; Yogesh, P.; Kannan, A.

2012-01-01

Intrusion detection systems were used in the past along with various techniques to detect intrusions in networks effectively. However, most of these systems are able to detect the intruders only with high false alarm rate. In this paper, we propose a new intelligent agent-based intrusion detection model for mobile ad hoc networks using a combination of attribute selection, outlier detection, and enhanced multiclass SVM classification methods. For this purpose, an effective preprocessing technique is proposed that improves the detection accuracy and reduces the processing time. Moreover, two new algorithms, namely, an Intelligent Agent Weighted Distance Outlier Detection algorithm and an Intelligent Agent-based Enhanced Multiclass Support Vector Machine algorithm are proposed for detecting the intruders in a distributed database environment that uses intelligent agents for trust management and coordination in transaction processing. The experimental results of the proposed model show that this system detects anomalies with low false alarm rate and high-detection rate when tested with KDD Cup 99 data set. PMID:23056036

Automated Nucleic Acid Extraction Systems for Detecting Cytomegalovirus and Epstein-Barr Virus Using Real-Time PCR: A Comparison Study Between the QIAsymphony RGQ and QIAcube Systems.

PubMed

Kim, Hanah; Hur, Mina; Kim, Ji Young; Moon, Hee Won; Yun, Yeo Min; Cho, Hyun Chan

2017-03-01

Cytomegalovirus (CMV) and Epstein-Barr virus (EBV) are increasingly important in immunocompromised patients. Nucleic acid extraction methods could affect the results of viral nucleic acid amplification tests. We compared two automated nucleic acid extraction systems for detecting CMV and EBV using real-time PCR assays. One hundred and fifty-three whole blood (WB) samples were tested for CMV detection, and 117 WB samples were tested for EBV detection. Viral nucleic acid was extracted in parallel by using QIAsymphony RGQ and QIAcube (Qiagen GmbH, Germany), and real-time PCR assays for CMV and EBV were performed with a Rotor-Gene Q real-time PCR cycler (Qiagen). Detection rates for CMV and EBV were compared, and agreements between the two systems were analyzed. The detection rate of CMV and EBV differed significantly between the QIAsymphony RGQ and QIAcube systems (CMV, 59.5% [91/153] vs 43.8% [67/153], P=0.0005; EBV, 59.0% [69/117] vs 42.7% [50/117], P=0.0008). The two systems showed moderate agreement for CMV and EBV detection (kappa=0.43 and 0.52, respectively). QIAsymphony RGQ showed a negligible correlation with QIAcube for quantitative EBV detection. QIAcube exhibited EBV PCR inhibition in 23.9% (28/117) of samples. Automated nucleic acid extraction systems have different performances and significantly affect the detection of viral pathogens. The QIAsymphony RGQ system appears to be superior to the QIAcube system for detecting CMV and EBV. A suitable sample preparation system should be considered for optimized nucleic acid amplification in clinical laboratories.

Research on moving object detection based on frog's eyes

NASA Astrophysics Data System (ADS)

Fu, Hongwei; Li, Dongguang; Zhang, Xinyuan

2008-12-01

On the basis of object's information processing mechanism with frog's eyes, this paper discussed a bionic detection technology which suitable for object's information processing based on frog's vision. First, the bionics detection theory by imitating frog vision is established, it is an parallel processing mechanism which including pick-up and pretreatment of object's information, parallel separating of digital image, parallel processing, and information synthesis. The computer vision detection system is described to detect moving objects which has special color, special shape, the experiment indicates that it can scheme out the detecting result in the certain interfered background can be detected. A moving objects detection electro-model by imitating biologic vision based on frog's eyes is established, the video simulative signal is digital firstly in this system, then the digital signal is parallel separated by FPGA. IN the parallel processing, the video information can be caught, processed and displayed in the same time, the information fusion is taken by DSP HPI ports, in order to transmit the data which processed by DSP. This system can watch the bigger visual field and get higher image resolution than ordinary monitor systems. In summary, simulative experiments for edge detection of moving object with canny algorithm based on this system indicate that this system can detect the edge of moving objects in real time, the feasibility of bionic model was fully demonstrated in the engineering system, and it laid a solid foundation for the future study of detection technology by imitating biologic vision.

Development of gas fire detection system using tunable diode laser absorption spectroscopy

NASA Astrophysics Data System (ADS)

Jiang, Y. L.; Li, G.; Yang, T.; Wang, J. J.

2017-01-01

The conventional fire detection methods mainly produce an alarm through detecting the changes in smoke concentration, flame radiation, heat and other physical parameters in the environment, but are unable to provide an early warning of a fire emergency. We have designed a gas fire detection system with a high detection sensitivity and high selectivity using the tunable semiconductor diode laser as a light source and combining wavelength modulation and harmonic detection technology. This system can invert the second harmonic signal obtained to obtain the concentration of carbon monoxide gas (a fire characteristic gas) so as to provide an early warning of fire. We reduce the system offset noise and the background noise generated due to the laser interference by deducting the system background spectrum lines from the second harmonic signal. This can also eliminate the interference of other gas spectral lines to a large extent. We detected the concentration of the carbon monoxide gas generated in smoldering sandalwood fire and open beech wood fire with the homemade fire simulator, and tested the lowest detectable limit of system. The test results show that the lowest detectable limit can reach 5×10-6 the system can maintain stable operation for a long period of time and can automatically trigger a water mist fire extinguishing system, which can fully meet the needs of early fire warning.

On resilience studies of system detection and recovery techniques against stealthy insider attacks

NASA Astrophysics Data System (ADS)

Wei, Sixiao; Zhang, Hanlin; Chen, Genshe; Shen, Dan; Yu, Wei; Pham, Khanh D.; Blasch, Erik P.; Cruz, Jose B.

2016-05-01

With the explosive growth of network technologies, insider attacks have become a major concern to business operations that largely rely on computer networks. To better detect insider attacks that marginally manipulate network traffic over time, and to recover the system from attacks, in this paper we implement a temporal-based detection scheme using the sequential hypothesis testing technique. Two hypothetical states are considered: the null hypothesis that the collected information is from benign historical traffic and the alternative hypothesis that the network is under attack. The objective of such a detection scheme is to recognize the change within the shortest time by comparing the two defined hypotheses. In addition, once the attack is detected, a server migration-based system recovery scheme can be triggered to recover the system to the state prior to the attack. To understand mitigation of insider attacks, a multi-functional web display of the detection analysis was developed for real-time analytic. Experiments using real-world traffic traces evaluate the effectiveness of Detection System and Recovery (DeSyAR) scheme. The evaluation data validates the detection scheme based on sequential hypothesis testing and the server migration-based system recovery scheme can perform well in effectively detecting insider attacks and recovering the system under attack.

State-Based Network Intrusion Detection Systems for SCADA Protocols: A Proof of Concept

NASA Astrophysics Data System (ADS)

Carcano, Andrea; Fovino, Igor Nai; Masera, Marcelo; Trombetta, Alberto

We present a novel Intrusion Detection System able to detect complex attacks to SCADA systems. By complex attack, we mean a set of commands (carried in Modbus packets) that, while licit when considered in isolation on a single-packet basis, interfere with the correct behavior of the system. The proposed IDS detects such attacks thanks to an internal representation of the controlled SCADA system and a corresponding rule language, powerful enough to express the system's critical states. Furthermore, we detail the implementation and provide experimental comparative results.

Study on nondestructive detection system based on x-ray for wire ropes conveyer belt

NASA Astrophysics Data System (ADS)

Miao, Changyun; Shi, Boya; Wan, Peng; Li, Jie

2008-03-01

A nondestructive detection system based on X-ray for wire ropes conveyer belt is designed by X-ray detection technology. In this paper X-ray detection principle is analyzed, a design scheme of the system is presented; image processing of conveyer belt is researched and image processing algorithms are given; X-ray acquisition receiving board is designed with the use of FPGA and DSP; the software of the system is programmed by C#.NET on WINXP/WIN2000 platform. The experiment indicates the system can implement remote real-time detection of wire ropes conveyer belt images, find faults and give an alarm in time. The system is direct perceived, strong real-time and high accurate. It can be used for fault detection of wire ropes conveyer belts in mines, ports, terminals and other fields.

A Support System for Mouse Operations Using Eye-Gaze Input

NASA Astrophysics Data System (ADS)

Abe, Kiyohiko; Nakayama, Yasuhiro; Ohi, Shoichi; Ohyama, Minoru

We have developed an eye-gaze input system for people with severe physical disabilities, such as amyotrophic lateral sclerosis (ALS) patients. This system utilizes a personal computer and a home video camera to detect eye-gaze under natural light. The system detects both vertical and horizontal eye-gaze by simple image analysis, and does not require special image processing units or sensors. Our conventional eye-gaze input system can detect horizontal eye-gaze with a high degree of accuracy. However, it can only classify vertical eye-gaze into 3 directions (up, middle and down). In this paper, we propose a new method for vertical eye-gaze detection. This method utilizes the limbus tracking method for vertical eye-gaze detection. Therefore our new eye-gaze input system can detect the two-dimension coordinates of user's gazing point. By using this method, we develop a new support system for mouse operation. This system can move the mouse cursor to user's gazing point.

Development of a Sensitive Luciferase-Based Sandwich ELISA System for the Detection of Human Extracellular Matrix 1 Protein.

PubMed

Li, Ya; Li, Yanqing; Zhao, Junli; Zheng, Xiaojing; Mao, Qinwen; Xia, Haibin

2016-12-01

Enzyme-linked immunosorbent assay (ELISA) has been one of the main methods for detecting an antigen in an aqueous sample for more than four decades. Nowadays, one of the biggest concerns for ELISA is still how to improve the sensitivity of the assay, and the luciferase-luciferin reaction system has been noticed as a new detection method with high sensitivity. In this study, a luciferin-luciferase reaction system was used as the detection method for a sandwich ELISA system. It was shown that this new system led to an increase in the detection sensitivity of at least two times when compared with the traditional horseradish peroxidase (HRP) detection method. Lastly, the serum levels of the human extracellular matrix 1 protein of breast cancer patients were determined by the new system, which were overall similar to the HRP chemiluminescent system. Furthermore, this new luciferase reporter can be implemented into other ELISA systems for the purpose of increasing the assay sensitivity.

An ultra-small, multi-point, and multi-color photo-detection system with high sensitivity and high dynamic range.

PubMed

Anazawa, Takashi; Yamazaki, Motohiro

2017-12-05

Although multi-point, multi-color fluorescence-detection systems are widely used in various sciences, they would find wider applications if they are miniaturized. Accordingly, an ultra-small, four-emission-point and four-color fluorescence-detection system was developed. Its size (space between emission points and a detection plane) is 15 × 10 × 12 mm, which is three-orders-of-magnitude smaller than that of a conventional system. Fluorescence from four emission points with an interval of 1 mm on the same plane was respectively collimated by four lenses and split into four color fluxes by four dichroic mirrors. Then, a total of sixteen parallel color fluxes were directly input into an image sensor and simultaneously detected. The emission-point plane and the detection plane (the image-sensor surface) were parallel and separated by a distance of only 12 mm. The developed system was applied to four-capillary array electrophoresis and successfully achieved Sanger DNA sequencing. Moreover, compared with a conventional system, the developed system had equivalent high fluorescence-detection sensitivity (lower detection limit of 17 pM dROX) and 1.6-orders-of-magnitude higher dynamic range (4.3 orders of magnitude).

Anomaly-based intrusion detection for SCADA systems

DOE Office of Scientific and Technical Information (OSTI.GOV)

Yang, D.; Usynin, A.; Hines, J. W.

2006-07-01

Most critical infrastructure such as chemical processing plants, electrical generation and distribution networks, and gas distribution is monitored and controlled by Supervisory Control and Data Acquisition Systems (SCADA. These systems have been the focus of increased security and there are concerns that they could be the target of international terrorists. With the constantly growing number of internet related computer attacks, there is evidence that our critical infrastructure may also be vulnerable. Researchers estimate that malicious online actions may cause $75 billion at 2007. One of the interesting countermeasures for enhancing information system security is called intrusion detection. This paper willmore » briefly discuss the history of research in intrusion detection techniques and introduce the two basic detection approaches: signature detection and anomaly detection. Finally, it presents the application of techniques developed for monitoring critical process systems, such as nuclear power plants, to anomaly intrusion detection. The method uses an auto-associative kernel regression (AAKR) model coupled with the statistical probability ratio test (SPRT) and applied to a simulated SCADA system. The results show that these methods can be generally used to detect a variety of common attacks. (authors)« less

The feasibility test of state-of-the-art face detection algorithms for vehicle occupant detection

NASA Astrophysics Data System (ADS)

Makrushin, Andrey; Dittmann, Jana; Vielhauer, Claus; Langnickel, Mirko; Kraetzer, Christian

2010-01-01

Vehicle seat occupancy detection systems are designed to prevent the deployment of airbags at unoccupied seats, thus avoiding the considerable cost imposed by the replacement of airbags. Occupancy detection can also improve passenger comfort, e.g. by activating air-conditioning systems. The most promising development perspectives are seen in optical sensing systems which have become cheaper and smaller in recent years. The most plausible way to check the seat occupancy by occupants is the detection of presence and location of heads, or more precisely, faces. This paper compares the detection performances of the three most commonly used and widely available face detection algorithms: Viola- Jones, Kienzle et al. and Nilsson et al. The main objective of this work is to identify whether one of these systems is suitable for use in a vehicle environment with variable and mostly non-uniform illumination conditions, and whether any one face detection system can be sufficient for seat occupancy detection. The evaluation of detection performance is based on a large database comprising 53,928 video frames containing proprietary data collected from 39 persons of both sexes and different ages and body height as well as different objects such as bags and rearward/forward facing child restraint systems.

Consistent detection of global predicates

NASA Technical Reports Server (NTRS)

Cooper, Robert; Marzullo, Keith

1991-01-01

A fundamental problem in debugging and monitoring is detecting whether the state of a system satisfies some predicate. If the system is distributed, then the resulting uncertainty in the state of the system makes such detection, in general, ill-defined. Three algorithms are presented for detecting global predicates in a well-defined way. These algorithms do so by interpreting predicates with respect to the communication that has occurred in the system.

System and Method for Multi-Wavelength Optical Signal Detection

NASA Technical Reports Server (NTRS)

McGlone, Thomas D. (Inventor)

2017-01-01

The system and method for multi-wavelength optical signal detection enables the detection of optical signal levels significantly below those processed at the discrete circuit level by the use of mixed-signal processing methods implemented with integrated circuit technologies. The present invention is configured to detect and process small signals, which enables the reduction of the optical power required to stimulate detection networks, and lowers the required laser power to make specific measurements. The present invention provides an adaptation of active pixel networks combined with mixed-signal processing methods to provide an integer representation of the received signal as an output. The present invention also provides multi-wavelength laser detection circuits for use in various systems, such as a differential absorption light detection and ranging system.

Video-based real-time on-street parking occupancy detection system

NASA Astrophysics Data System (ADS)

Bulan, Orhan; Loce, Robert P.; Wu, Wencheng; Wang, YaoRong; Bernal, Edgar A.; Fan, Zhigang

2013-10-01

Urban parking management is receiving significant attention due to its potential to reduce traffic congestion, fuel consumption, and emissions. Real-time parking occupancy detection is a critical component of on-street parking management systems, where occupancy information is relayed to drivers via smart phone apps, radio, Internet, on-road signs, or global positioning system auxiliary signals. Video-based parking occupancy detection systems can provide a cost-effective solution to the sensing task while providing additional functionality for traffic law enforcement and surveillance. We present a video-based on-street parking occupancy detection system that can operate in real time. Our system accounts for the inherent challenges that exist in on-street parking settings, including illumination changes, rain, shadows, occlusions, and camera motion. Our method utilizes several components from video processing and computer vision for motion detection, background subtraction, and vehicle detection. We also present three traffic law enforcement applications: parking angle violation detection, parking boundary violation detection, and exclusion zone violation detection, which can be integrated into the parking occupancy cameras as a value-added option. Our experimental results show that the proposed parking occupancy detection method performs in real-time at 5 frames/s and achieves better than 90% detection accuracy across several days of videos captured in a busy street block under various weather conditions such as sunny, cloudy, and rainy, among others.

GPU based cloud system for high-performance arrhythmia detection with parallel k-NN algorithm.

PubMed

Tae Joon Jun; Hyun Ji Park; Hyuk Yoo; Young-Hak Kim; Daeyoung Kim

2016-08-01

In this paper, we propose an GPU based Cloud system for high-performance arrhythmia detection. Pan-Tompkins algorithm is used for QRS detection and we optimized beat classification algorithm with K-Nearest Neighbor (K-NN). To support high performance beat classification on the system, we parallelized beat classification algorithm with CUDA to execute the algorithm on virtualized GPU devices on the Cloud system. MIT-BIH Arrhythmia database is used for validation of the algorithm. The system achieved about 93.5% of detection rate which is comparable to previous researches while our algorithm shows 2.5 times faster execution time compared to CPU only detection algorithm.

Note: An improved 3D imaging system for electron-electron coincidence measurements

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lin, Yun Fei; Lee, Suk Kyoung; Adhikari, Pradip

We demonstrate an improved imaging system that can achieve highly efficient 3D detection of two electrons in coincidence. The imaging system is based on a fast frame complementary metal-oxide semiconductor camera and a high-speed waveform digitizer. We have shown previously that this detection system is capable of 3D detection of ions and electrons with good temporal and spatial resolution. Here, we show that with a new timing analysis algorithm, this system can achieve an unprecedented dead-time (<0.7 ns) and dead-space (<1 mm) when detecting two electrons. A true zero dead-time detection is also demonstrated.

Early Forest Fire Detection Using Radio-Acoustic Sounding System

PubMed Central

Sahin, Yasar Guneri; Ince, Turker

2009-01-01

Automated early fire detection systems have recently received a significant amount of attention due to their importance in protecting the global environment. Some emergent technologies such as ground-based, satellite-based remote sensing and distributed sensor networks systems have been used to detect forest fires in the early stages. In this study, a radio-acoustic sounding system with fine space and time resolution capabilities for continuous monitoring and early detection of forest fires is proposed. Simulations show that remote thermal mapping of a particular forest region by the proposed system could be a potential solution to the problem of early detection of forest fires. PMID:22573967

Note: An improved 3D imaging system for electron-electron coincidence measurements

NASA Astrophysics Data System (ADS)

Lin, Yun Fei; Lee, Suk Kyoung; Adhikari, Pradip; Herath, Thushani; Lingenfelter, Steven; Winney, Alexander H.; Li, Wen

2015-09-01

We demonstrate an improved imaging system that can achieve highly efficient 3D detection of two electrons in coincidence. The imaging system is based on a fast frame complementary metal-oxide semiconductor camera and a high-speed waveform digitizer. We have shown previously that this detection system is capable of 3D detection of ions and electrons with good temporal and spatial resolution. Here, we show that with a new timing analysis algorithm, this system can achieve an unprecedented dead-time (<0.7 ns) and dead-space (<1 mm) when detecting two electrons. A true zero dead-time detection is also demonstrated.

Optimization of optical systems.

PubMed

Champagne, E B

1966-11-01

The power signal-to-noise ratios for coherent and noncoherent optical detection are presented, with the expression for noncoherent detection being examined in detail. It is found that for the long range optical system to compete with its microwave counterpart it is necessary to optimize the optical system. The optical system may be optimized by using coherent detection, or noncoherent detection if the signal is the dominate noise factor. A design procedure is presented which, in principle, always allows one to obtain signal shot-noise limited operation with noncoherent detection if pulsed operation is used. The technique should make reasonable extremely long range, high data rate systems of relatively simple design.

Road detection and buried object detection in elevated EO/IR imagery

NASA Astrophysics Data System (ADS)

Kennedy, Levi; Kolba, Mark P.; Walters, Joshua R.

2012-06-01

To assist the warfighter in visually identifying potentially dangerous roadside objects, the U.S. Army RDECOM CERDEC Night Vision and Electronic Sensors Directorate (NVESD) has developed an elevated video sensor system testbed for data collection. This system provides color and mid-wave infrared (MWIR) imagery. Signal Innovations Group (SIG) has developed an automated processing capability that detects the road within the sensor field of view and identifies potentially threatening buried objects within the detected road. The road detection algorithm leverages system metadata to project the collected imagery onto a flat ground plane, allowing for more accurate detection of the road as well as the direct specification of realistic physical constraints in the shape of the detected road. Once the road has been detected in an image frame, a buried object detection algorithm is applied to search for threatening objects within the detected road space. The buried object detection algorithm leverages textural and pixel intensity-based features to detect potential anomalies and then classifies them as threatening or non-threatening objects. Both the road detection and the buried object detection algorithms have been developed to facilitate their implementation in real-time in the NVESD system.

[A review of mixed gas detection system based on infrared spectroscopic technique].

PubMed

Dang, Jing-Min; Fu, Li; Yan, Zi-Hui; Zheng, Chuan-Tao; Chang, Yu-Chun; Chen, Chen; Wang, Yi-Din

2014-10-01

In order to provide the experiences and references to the researchers who are working on infrared (IR) mixed gas detection field. The proposed manuscript reviews two sections of the aforementioned field, including optical multiplexing structure and detection method. At present, the coherent light sources whose representative are quantum cascade laser (QCL) and inter-band cascade laser(ICL) become the mainstream light source in IR mixed gas detection, which replace the traditional non-coherent light source, such as IR radiation source and IR light emitting diode. In addition, the photon detector which has a super high detectivity and very short response time is gradually beyond thermal infrared detector, dominant in the field of infrared detector. The optical multiplexing structure is the key factor of IR mixed gas detection system, which consists of single light source multi-plexing detection structure and multi light source multiplexing detection structure. Particularly, single light source multiplexing detection structure is advantages of small volume and high integration, which make it a plausible candidate for the portable mixed gas detection system; Meanwhile, multi light source multiplexing detection structure is embodiment of time division multiplex, frequency division multiplexing and wavelength division multiplexing, and become the leading structure of the mixed gas detection system because of its wider spectral range, higher spectral resolution, etc. The detection method applied to IR mixed gas detection includes non-dispersive infrared (NDIR) spectroscopy, wavelength and frequency-modulation spectroscopy, cavity-enhanced spectroscopy and photoacoustic spectroscopy, etc. The IR mixed gas detection system designed by researchers after recognizing the whole sections of the proposed system, which play a significant role in industrial and agricultural production, environmental monitoring, and life science, etc.

A group filter algorithm for sea mine detection

NASA Astrophysics Data System (ADS)

Cobb, J. Tory; An, Myoung; Tolimieri, Richard

2005-06-01

Automatic detection of sea mines in coastal regions is a difficult task due to the highly variable sea bottom conditions present in the underwater environment. Detection systems must be able to discriminate objects which vary in size, shape, and orientation from naturally occurring and man-made clutter. Additionally, these automated systems must be computationally efficient to be incorporated into unmanned underwater vehicle (UUV) sensor systems characterized by high sensor data rates and limited processing abilities. Using noncommutative group harmonic analysis, a fast, robust sea mine detection system is created. A family of unitary image transforms associated to noncommutative groups is generated and applied to side scan sonar image files supplied by Naval Surface Warfare Center Panama City (NSWC PC). These transforms project key image features, geometrically defined structures with orientations, and localized spectral information into distinct orthogonal components or feature subspaces of the image. The performance of the detection system is compared against the performance of an independent detection system in terms of probability of detection (Pd) and probability of false alarm (Pfa).

Lexington incident detection system evaluation report : final report.

DOT National Transportation Integrated Search

2005-11-01

This report describes the evaluation of an experimental incident detection system implemented within the Lexington/Fayette County area by the Lexington Fayette Urban County Government Department of Traffic Engineering. The incident detection system i...

Colleges Fight Fire With Electronics.

ERIC Educational Resources Information Center

College & University Business, 1968

1968-01-01

Description of various electronic fire detection and alarm systems is presented. Explanation of detective systems includes--(1) fixed-temperature and rate-of-rise heat sensitive devices, (2) smoke detective devices, (3) ionization systems, and (4) infrared and ultraviolet radiation devices. Each system type is evaluated in terms of operation,…

Evaluation of a Portable Microchip Electrophoresis Fluorescence Detection System for the Analysis of Amino Acid Neurotransmitters in Brain Dialysis Samples

PubMed Central

OBORNY, Nathan J.; COSTA, Elton E. Melo; SUNTORNSUK, Leena; ABREU, Fabiane C.; LUNTE, Susan M.

2016-01-01

A portable fluorescence detection system for use with microchip electrophoresis was developed and compared to a benchtop system. Using this system, six neuroactive amines commonly found in brain dialysate—arginine, citrulline, taurine, histamine, glutamate, and aspartate—were derivatized offline with naphthalene-2,3-dicarboxaldehyde/cyanide, separated electrophoretically, and detected by fluorescence. Limits of detection for the analytes of interest were 50nM – 250nM for the benchtop system and 250 nM – 1.3 μM for the portable system, both of which were adequate for analyte determination in brain microdialysis samples. The portable system was then demonstrated for the detection of the same six amines in a rat brain microdialysis sample. PMID:26753703

Feasibility of fast neutron analysis for the detection of explosives buried in soil

NASA Astrophysics Data System (ADS)

Faust, A. A.; McFee, J. E.; Bowman, C. L.; Mosquera, C.; Andrews, H. R.; Kovaltchouk, V. D.; Ing, H.

2011-12-01

A commercialized thermal neutron analysis (TNA) sensor has been developed to confirm the presence of buried bulk explosives as part of a multi-sensor anti-tank landmine detection system. Continuing improvements to the TNA system have included the use of an electronic pulsed neutron generator that offers the possibility of applying fast neutron analysis (FNA) methods to improve the system's detection capability. This paper describes an investigation into the use of FNA as a complementary component in such a TNA system. The results of a modeling study using simple geometries and a full model of the TNA sensor head are presented, as well as preliminary results from an experimental associated particle imaging (API) system that supports the modeling study results. The investigation has concluded that the pulsed beam FNA approach would not improve the detection performance of a TNA system for landmine or buried IED detection in a confirmation role, and could not be made into a practical stand-alone detection system for buried anti-tank landmines. Detection of buried landmines and IEDs by FNA remains a possibility, however, through the use of the API technique.

Vision-based object detection and recognition system for intelligent vehicles

NASA Astrophysics Data System (ADS)

Ran, Bin; Liu, Henry X.; Martono, Wilfung

1999-01-01

Recently, a proactive crash mitigation system is proposed to enhance the crash avoidance and survivability of the Intelligent Vehicles. Accurate object detection and recognition system is a prerequisite for a proactive crash mitigation system, as system component deployment algorithms rely on accurate hazard detection, recognition, and tracking information. In this paper, we present a vision-based approach to detect and recognize vehicles and traffic signs, obtain their information, and track multiple objects by using a sequence of color images taken from a moving vehicle. The entire system consist of two sub-systems, the vehicle detection and recognition sub-system and traffic sign detection and recognition sub-system. Both of the sub- systems consist of four models: object detection model, object recognition model, object information model, and object tracking model. In order to detect potential objects on the road, several features of the objects are investigated, which include symmetrical shape and aspect ratio of a vehicle and color and shape information of the signs. A two-layer neural network is trained to recognize different types of vehicles and a parameterized traffic sign model is established in the process of recognizing a sign. Tracking is accomplished by combining the analysis of single image frame with the analysis of consecutive image frames. The analysis of the single image frame is performed every ten full-size images. The information model will obtain the information related to the object, such as time to collision for the object vehicle and relative distance from the traffic sings. Experimental results demonstrated a robust and accurate system in real time object detection and recognition over thousands of image frames.

Effect of agitation and terminal subcultures on yield and speed of detection of the Oxoid Signal blood culture system versus the BACTEC radiometric system

DOE Office of Scientific and Technical Information (OSTI.GOV)

Weinstein, M.P.; Mirrett, S.; Reimer, L.G.

1989-03-01

In an initial evaluation, we found the Oxoid Signal blood culture system inferior to the BACTEC radiometric system for detection of some microorganisms causing septicemia. To determine whether modified processing of the Oxoid Signal blood culture system could improve its yield and speed of detecting positive cultures relative to the BACTEC radiometric system, we agitated all Oxoid bottles during the first 24 to 48 h of incubation and performed aerobic and anaerobic subcultures of all Oxoid bottles negative after 7 days of incubation. These modifications improved the overall performance of the Oxoid system, particularly with regard to the yield ofmore » streptococci, members of the family Enterobacteriaceae, and Haemophilus, Neisseria, and Acinetobacter spp. The speed of detecting positive cultures also was improved, especially within the first 24 h of incubation. However, the BACTEC system still detected more positive cultures (P less than 0.005), especially of obligate aerobes such as Pseudomonas aeruginosa (P less than 0.05) and yeasts (P less than 0.005). The BACTEC system also detected positive cultures earlier than the Oxoid system (e.g., at 24 h of incubation, 70.5% of BACTEC positive cultures detected versus 62.1% of Oxoid positive cultures detected). Further modifications of the Oxoid system which might include a revised medium, additional processing modifications, altered headspace atmosphere, or a complementary second broth medium should be considered, since the system is attractive in concept and is easy to use in the clinical laboratory.« less

Active Detection for Exposing Intelligent Attacks in Control Systems

DOE Office of Scientific and Technical Information (OSTI.GOV)

Weerakkody, Sean; Ozel, Omur; Griffioen, Paul

In this paper, we consider approaches for detecting integrity attacks carried out by intelligent and resourceful adversaries in control systems. Passive detection techniques are often incorporated to identify malicious behavior. Here, the defender utilizes finely-tuned algorithms to process information and make a binary decision, whether the system is healthy or under attack. We demonstrate that passive detection can be ineffective against adversaries with model knowledge and access to a set of input/output channels. We then propose active detection as a tool to detect attacks. In active detection, the defender leverages degrees of freedom he has in the system to detectmore » the adversary. Specifically, the defender will introduce a physical secret kept hidden from the adversary, which can be utilized to authenticate the dynamics. In this regard, we carefully review two approaches for active detection: physical watermarking at the control input, and a moving target approach for generating system dynamics. We examine practical considerations for implementing these technologies and discuss future research directions.« less

Investigation of an Optimum Detection Scheme for a Star-Field Mapping System

NASA Technical Reports Server (NTRS)

Aldridge, M. D.; Credeur, L.

1970-01-01

An investigation was made to determine the optimum detection scheme for a star-field mapping system that uses coded detection resulting from starlight shining through specially arranged multiple slits of a reticle. The computer solution of equations derived from a theoretical model showed that the greatest probability of detection for a given star and background intensity occurred with the use of a single transparent slit. However, use of multiple slits improved the system's ability to reject the detection of undesirable lower intensity stars, but only by decreasing the probability of detection for lower intensity stars to be mapped. Also, it was found that the coding arrangement affected the root-mean-square star-position error and that detection is possible with error in the system's detected spin rate, though at a reduced probability.

Highly-sensitive and large-dynamic diffuse optical tomography system for breast tumor detection

NASA Astrophysics Data System (ADS)

Du, Wenwen; Zhang, Limin; Yin, Guoyan; Zhang, Yanqi; Zhao, Huijuan; Gao, Feng

2018-02-01

Diffuse optical tomography (DOT) as a new functional imaging has important clinical applications in many aspects such as benign and malignant breast tumor detection, tumor staging and so on. For quantitative detection of breast tumor, a three-wavelength continuous-wave DOT prototype system combined the ultra-high sensitivity of the photon-counting detection and the measurement parallelism of the lock-in technique was developed to provide high temporal resolution, high sensitivity, large dynamic detection range and signal-to-noise ratio. Additionally, a CT-analogous scanning mode was proposed to cost-effectively increase the detection data. To evaluate the feasibility of the system, a series of assessments were conducted. The results demonstrate that the system can obtain high linearity, stability and negligible inter-wavelength crosstalk. The preliminary phantom experiments show the absorption coefficient is able to be successfully reconstructed, indicating that the system is one of the ideal platforms for optical breast tumor detection.

Damage Detection Sensor System for Aerospace and Multiple Applications

NASA Technical Reports Server (NTRS)

Williams, M.; Lewis, M.; Gibson, T.; Medelius, P.; Lane, J.

2017-01-01

The damage detection sensory system is an intelligent damage detection ‘skin’ that can be embedded into rigid or flexible structures, providing a lightweight capability for in-situ health monitoring for applications such as spacecraft, expandable or inflatable structures, extravehicular activities (EVA) suits, smart wearables, and other applications where diagnostic impact damage monitoring might be critical. The sensor systems can be customized for detecting location, damage size, and depth, with velocity options and can be designed for particular environments for monitoring of impact or physical damage to a structure. The operation of the sensor detection system is currently based on the use of parallel conductive traces placed on a firm or flexible surface. Several detection layers can be implemented, where alternate layers are arranged in orthogonal direction with respect to the adjacent layers allowing for location and depth calculations. Increased flexibility of the damage detection sensor system designs will also be introduced.

Toward detecting deception in intelligent systems

NASA Astrophysics Data System (ADS)

Santos, Eugene, Jr.; Johnson, Gregory, Jr.

2004-08-01

Contemporary decision makers often must choose a course of action using knowledge from several sources. Knowledge may be provided from many diverse sources including electronic sources such as knowledge-based diagnostic or decision support systems or through data mining techniques. As the decision maker becomes more dependent on these electronic information sources, detecting deceptive information from these sources becomes vital to making a correct, or at least more informed, decision. This applies to unintentional disinformation as well as intentional misinformation. Our ongoing research focuses on employing models of deception and deception detection from the fields of psychology and cognitive science to these systems as well as implementing deception detection algorithms for probabilistic intelligent systems. The deception detection algorithms are used to detect, classify and correct attempts at deception. Algorithms for detecting unexpected information rely upon a prediction algorithm from the collaborative filtering domain to predict agent responses in a multi-agent system.

Factors influencing performance of internet-based biosurveillance systems used in epidemic intelligence for early detection of infectious diseases outbreaks.

PubMed

Barboza, Philippe; Vaillant, Laetitia; Le Strat, Yann; Hartley, David M; Nelson, Noele P; Mawudeku, Abla; Madoff, Lawrence C; Linge, Jens P; Collier, Nigel; Brownstein, John S; Astagneau, Pascal

2014-01-01

Internet-based biosurveillance systems have been developed to detect health threats using information available on the Internet, but system performance has not been assessed relative to end-user needs and perspectives. Infectious disease events from the French Institute for Public Health Surveillance (InVS) weekly international epidemiological bulletin published in 2010 were used to construct the gold-standard official dataset. Data from six biosurveillance systems were used to detect raw signals (infectious disease events from informal Internet sources): Argus, BioCaster, GPHIN, HealthMap, MedISys and ProMED-mail. Crude detection rates (C-DR), crude sensitivity rates (C-Se) and intrinsic sensitivity rates (I-Se) were calculated from multivariable regressions to evaluate the systems' performance (events detected compared to the gold-standard) 472 raw signals (Internet disease reports) related to the 86 events included in the gold-standard data set were retrieved from the six systems. 84 events were detected before their publication in the gold-standard. The type of sources utilised by the systems varied significantly (p<0001). I-Se varied significantly from 43% to 71% (p=0001) whereas other indicators were similar (C-DR: p=020; C-Se, p=013). I-Se was significantly associated with individual systems, types of system, languages, regions of occurrence, and types of infectious disease. Conversely, no statistical difference of C-DR was observed after adjustment for other variables. Although differences could result from a biosurveillance system's conceptual design, findings suggest that the combined expertise amongst systems enhances early detection performance for detection of infectious diseases. While all systems showed similar early detection performance, systems including human moderation were found to have a 53% higher I-Se (p=00001) after adjustment for other variables. Overall, the use of moderation, sources, languages, regions of occurrence, and types of cases were found to influence system performance.

Towards an integrated defense system for cyber security situation awareness experiment

NASA Astrophysics Data System (ADS)

Zhang, Hanlin; Wei, Sixiao; Ge, Linqiang; Shen, Dan; Yu, Wei; Blasch, Erik P.; Pham, Khanh D.; Chen, Genshe

2015-05-01

In this paper, an implemented defense system is demonstrated to carry out cyber security situation awareness. The developed system consists of distributed passive and active network sensors designed to effectively capture suspicious information associated with cyber threats, effective detection schemes to accurately distinguish attacks, and network actors to rapidly mitigate attacks. Based on the collected data from network sensors, image-based and signals-based detection schemes are implemented to detect attacks. To further mitigate attacks, deployed dynamic firewalls on hosts dynamically update detection information reported from the detection schemes and block attacks. The experimental results show the effectiveness of the proposed system. A future plan to design an effective defense system is also discussed based on system theory.

Design of oil pipeline leak detection and communication system based on optical fiber technology

NASA Astrophysics Data System (ADS)

Tu, Yaqing; Chen, Huabo

1999-08-01

The integrity of oil pipeline is always a major concern of operators. Pipeline leak not only leads to loss of oil, but pollutes environment. A new pipeline leak detection and communication system based on optical fiber technology to ensure the pipeline reliability is presented. Combined direct leak detection method with an indirect one, the system will greatly reduce the rate of false alarm. According, to the practical features of oil pipeline,the pipeline communication system is designed employing the state-of-the-art optic fiber communication technology. The system has such feature as high location accuracy of leak detection, good real-time characteristic, etc. which overcomes the disadvantages of traditional leak detection methods and communication system effectively.

46 CFR 108.404 - Selection of fire detection system.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 46 Shipping 4 2012-10-01 2012-10-01 false Selection of fire detection system. 108.404 Section 108.404 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) A-MOBILE OFFSHORE DRILLING UNITS DESIGN AND EQUIPMENT Fire Extinguishing Systems § 108.404 Selection of fire detection system. (a) If a...

46 CFR 108.411 - Smoke detection system.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 46 Shipping 4 2013-10-01 2013-10-01 false Smoke detection system. 108.411 Section 108.411 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) A-MOBILE OFFSHORE DRILLING UNITS DESIGN AND EQUIPMENT Fire Extinguishing Systems § 108.411 Smoke detection system. Each smoke accumulator in a smoke...

46 CFR 108.413 - Fusible element fire detection system.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 46 Shipping 4 2012-10-01 2012-10-01 false Fusible element fire detection system. 108.413 Section 108.413 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) A-MOBILE OFFSHORE DRILLING UNITS DESIGN AND EQUIPMENT Fire Extinguishing Systems § 108.413 Fusible element fire detection system...

46 CFR 108.411 - Smoke detection system.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 46 Shipping 4 2014-10-01 2014-10-01 false Smoke detection system. 108.411 Section 108.411 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) A-MOBILE OFFSHORE DRILLING UNITS DESIGN AND EQUIPMENT Fire Extinguishing Systems § 108.411 Smoke detection system. Each smoke accumulator in a smoke...

46 CFR 108.413 - Fusible element fire detection system.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 46 Shipping 4 2014-10-01 2014-10-01 false Fusible element fire detection system. 108.413 Section 108.413 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) A-MOBILE OFFSHORE DRILLING UNITS DESIGN AND EQUIPMENT Fire Extinguishing Systems § 108.413 Fusible element fire detection system...

46 CFR 108.404 - Selection of fire detection system.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 46 Shipping 4 2014-10-01 2014-10-01 false Selection of fire detection system. 108.404 Section 108.404 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) A-MOBILE OFFSHORE DRILLING UNITS DESIGN AND EQUIPMENT Fire Extinguishing Systems § 108.404 Selection of fire detection system. (a) If a...

46 CFR 108.413 - Fusible element fire detection system.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 46 Shipping 4 2013-10-01 2013-10-01 false Fusible element fire detection system. 108.413 Section 108.413 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) A-MOBILE OFFSHORE DRILLING UNITS DESIGN AND EQUIPMENT Fire Extinguishing Systems § 108.413 Fusible element fire detection system...

46 CFR 108.404 - Selection of fire detection system.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 46 Shipping 4 2013-10-01 2013-10-01 false Selection of fire detection system. 108.404 Section 108.404 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) A-MOBILE OFFSHORE DRILLING UNITS DESIGN AND EQUIPMENT Fire Extinguishing Systems § 108.404 Selection of fire detection system. (a) If a...

46 CFR 108.411 - Smoke detection system.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 4 2011-10-01 2011-10-01 false Smoke detection system. 108.411 Section 108.411 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) A-MOBILE OFFSHORE DRILLING UNITS DESIGN AND EQUIPMENT Fire Extinguishing Systems § 108.411 Smoke detection system. Each smoke accumulator in a smoke...

46 CFR 108.411 - Smoke detection system.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 46 Shipping 4 2012-10-01 2012-10-01 false Smoke detection system. 108.411 Section 108.411 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) A-MOBILE OFFSHORE DRILLING UNITS DESIGN AND EQUIPMENT Fire Extinguishing Systems § 108.411 Smoke detection system. Each smoke accumulator in a smoke...

46 CFR 108.404 - Selection of fire detection system.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 4 2011-10-01 2011-10-01 false Selection of fire detection system. 108.404 Section 108.404 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) A-MOBILE OFFSHORE DRILLING UNITS DESIGN AND EQUIPMENT Fire Extinguishing Systems § 108.404 Selection of fire detection system. (a) If a...

46 CFR 108.413 - Fusible element fire detection system.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 4 2011-10-01 2011-10-01 false Fusible element fire detection system. 108.413 Section 108.413 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) A-MOBILE OFFSHORE DRILLING UNITS DESIGN AND EQUIPMENT Fire Extinguishing Systems § 108.413 Fusible element fire detection system...

30 CFR 250.1629 - Additional production and fuel gas system requirements.

Code of Federal Regulations, 2014 CFR

2014-07-01

... structure. (4) Fire- and gas-detection system. (i) Fire (flame, heat, or smoke) sensors shall be installed... explosive limit. One approved method of providing adequate ventilation is a change of air volume each 5... detection systems shall be capable of continuous monitoring. Fire-detection systems and portions of...

30 CFR 250.1629 - Additional production and fuel gas system requirements.

Code of Federal Regulations, 2013 CFR

2013-07-01

... structure. (4) Fire- and gas-detection system. (i) Fire (flame, heat, or smoke) sensors shall be installed... explosive limit. One approved method of providing adequate ventilation is a change of air volume each 5... detection systems shall be capable of continuous monitoring. Fire-detection systems and portions of...

Market Survey: Biological Detectors. Guide for Selection of Detection Devices and Systems

DTIC Science & Technology

2006-02-01

samples. There are no real concerns with logistical or operational concerns, as issues such as size, weight, signature, transportation , additional equipment...of the detection system or device on support and logistical systems. 2.1 Transportation Measure. Ability to transport the detection system or device...supplied, such as water, fuel, batteries, chemical, power, etc.) that have to be transported to the site for detection. 100 0-1 consumable or

Luciferase-Zinc-Finger System for the Rapid Detection of Pathogenic Bacteria.

PubMed

Shi, Chu; Xu, Qing; Ge, Yue; Jiang, Ling; Huang, He

2017-08-09

Rapid and reliable detection of pathogenic bacteria is crucial for food safety control. Here, we present a novel luciferase-zinc finger system for the detection of pathogens that offers rapid and specific profiling. The system, which uses a zinc-finger protein domain to probe zinc finger recognition sites, was designed to bind the amplified conserved regions of 16S rDNA, and the obtained products were detected using a modified luciferase. The luciferase-zinc finger system not only maintained luciferase activity but also allowed the specific detection of different bacterial species, with a sensitivity as low as 10 copies and a linear range from 10 to 10 4 copies per microliter of the specific PCR product. Moreover, the system is robust and rapid, enabling the simultaneous detection of 6 species of bacteria in artificially contaminated samples with excellent accuracy. Thus, we envision that our luciferase-zinc finger system will have far-reaching applications.

An intelligent detecting system for permeability prediction of MBR.

PubMed

Han, Honggui; Zhang, Shuo; Qiao, Junfei; Wang, Xiaoshuang

2018-01-01

The membrane bioreactor (MBR) has been widely used to purify wastewater in wastewater treatment plants. However, a critical difficulty of the MBR is membrane fouling. To reduce membrane fouling, in this work, an intelligent detecting system is developed to evaluate the performance of MBR by predicting the membrane permeability. This intelligent detecting system consists of two main parts. First, a soft computing method, based on the partial least squares method and the recurrent fuzzy neural network, is designed to find the nonlinear relations between the membrane permeability and the other variables. Second, a complete new platform connecting the sensors and the software is built, in order to enable the intelligent detecting system to handle complex algorithms. Finally, the simulation and experimental results demonstrate the reliability and effectiveness of the proposed intelligent detecting system, underlying the potential of this system for the online membrane permeability for detecting membrane fouling of MBR.

SiPM electro-optical detection system noise suppression method

NASA Astrophysics Data System (ADS)

Bi, Xiangli; Yang, Suhui; Hu, Tao; Song, Yiheng

2014-11-01

In this paper, the single photon detection principle of Silicon Photomultipliers (SiPM) device is introduced. The main noise factors that infect the sensitivity of the electro-optical detection system are analyzed, including background light noise, detector dark noise, preamplifier noise and signal light noise etc. The Optical, electrical and thermodynamic methods are used to suppress the SiPM electro-optical detection system noise, which improved the response sensitivity of the detector. Using SiPM optoelectronic detector with a even high sensitivity, together with small field large aperture optical system, high cutoff narrow bandwidth filters, low-noise operational amplifier circuit, the modular design of functional circuit, semiconductor refrigeration technology, greatly improved the sensitivity of optical detection system, reduced system noise and achieved long-range detection of weak laser radiation signal. Theoretical analysis and experimental results show that the proposed methods are reasonable and efficient.

Subgenomic Reporter RNA System for Detection of Alphavirus Infection in Mosquitoes

PubMed Central

Steel, J. Jordan; Franz, Alexander W. E.; Sanchez-Vargas, Irma; Olson, Ken E.; Geiss, Brian J.

2013-01-01

Current methods for detecting real-time alphavirus (Family Togaviridae) infection in mosquitoes require the use of recombinant viruses engineered to express a visibly detectable reporter protein. These altered viruses expressing fluorescent proteins, usually from a duplicated viral subgenomic reporter, are effective at marking infection but tend to be attenuated due to the modification of the genome. Additionally, field strains of viruses cannot be visualized using this approach unless infectious clones can be developed to insert a reporter protein. To circumvent these issues, we have developed an insect cell-based system for detecting wild-type sindbis virus infection that uses a virus inducible promoter to express a fluorescent reporter gene only upon active virus infection. We have developed an insect expression system that produces sindbis virus minigenomes containing a subgenomic promoter sequence, which produces a translatable RNA species only when infectious virus is present and providing viral replication proteins. This subgenomic reporter RNA system is able to detect wild-type Sindbis infection in cultured mosquito cells. The detection system is relatively species specific and only detects closely related viruses, but can detect low levels of alphavirus specific replication early during infection. A chikungunya virus detection system was also developed that specifically detects chikungunya virus infection. Transgenic Aedes aegypti mosquito families were established that constitutively express the sindbis virus reporter RNA and were found to only express fluorescent proteins during virus infection. This virus inducible reporter system demonstrates a novel approach for detecting non-recombinant virus infection in mosquito cell culture and in live transgenic mosquitoes. PMID:24367703

Farm-specific economic value of automatic lameness detection systems in dairy cattle: From concepts to operational simulations.

PubMed

Van De Gucht, Tim; Saeys, Wouter; Van Meensel, Jef; Van Nuffel, Annelies; Vangeyte, Jurgen; Lauwers, Ludwig

2018-01-01

Although prototypes of automatic lameness detection systems for dairy cattle exist, information about their economic value is lacking. In this paper, a conceptual and operational framework for simulating the farm-specific economic value of automatic lameness detection systems was developed and tested on 4 system types: walkover pressure plates, walkover pressure mats, camera systems, and accelerometers. The conceptual framework maps essential factors that determine economic value (e.g., lameness prevalence, incidence and duration, lameness costs, detection performance, and their relationships). The operational simulation model links treatment costs and avoided losses with detection results and farm-specific information, such as herd size and lameness status. Results show that detection performance, herd size, discount rate, and system lifespan have a large influence on economic value. In addition, lameness prevalence influences the economic value, stressing the importance of an adequate prior estimation of the on-farm prevalence. The simulations provide first estimates for the upper limits for purchase prices of automatic detection systems. The framework allowed for identification of knowledge gaps obstructing more accurate economic value estimation. These include insights in cost reductions due to early detection and treatment, and links between specific lameness causes and their related losses. Because this model provides insight in the trade-offs between automatic detection systems' performance and investment price, it is a valuable tool to guide future research and developments. Copyright © 2018 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.

Molecular constituents of the extracellular matrix in rat liver mounting a hepatic progenitor cell response for tissue repair

PubMed Central

2013-01-01

Background Tissue repair in the adult mammalian liver occurs in two distinct processes, referred to as the first and second tiers of defense. We undertook to characterize the changes in molecular constituents of the extracellular matrix when hepatic progenitor cells (HPCs) respond in a second tier of defense to liver injury. Results We used transcriptional profiling on rat livers responding by a first tier (surgical removal of 70% of the liver mass (PHx protocol)) and a second tier (70% hepatectomy combined with exposure to 2-acetylaminofluorene (AAF/PHx protocol)) of defense to liver injury and compared the transcriptional signatures in untreated rat liver (control) with those from livers of day 1, day 5 and day 9 post hepatectomy in both protocols. Numerous transcripts encoding specific subunits of collagens, laminins, integrins, and various other extracellular matrix structural components were differentially up- or down-modulated (P < 0.01). The levels of a number of transcripts were significantly up-modulated, mainly in the second tier of defense (Agrn, Bgn, Fbn1, Col4a1, Col8a1, Col9a3, Lama5, Lamb1, Lamb2, Itga4, Igtb2, Itgb4, Itgb6, Nid2), and their signal intensities showed a strong or very strong correlation with Krt1-19, a well-established marker of a ductular/HPC reaction. Furthermore, a significant up-modulation and very strong correlation between the transcriptional profiles of Krt1-19 and St14 encoding matriptase, a component of a novel protease system, was found in the second tier of defense. Real-time PCR confirmed the modulation of St14 transcript levels and strong correlation to Krt-19 and also showed a significant up-modulation and strong correlation to Spint1 encoding HAI-1, a cognate inhibitor of matriptase. Immunodetection and three-dimensional reconstructions showed that laminin, Collagen1a1, agrin and nidogen1 surrounded bile ducts, proliferating cholangiocytes, and HPCs in ductular reactions regardless of the nature of defense. Similarly, matriptase and HAI-1 were expressed in cholangiocytes regardless of the tier of defense, but in the second tier of defense, a subpopulation of HPCs in ductular reactions co-expressed HAI-1 and the fetal hepatocyte marker Dlk1. Conclusion Transcriptional profiling and immunodetection, including three-dimensional reconstruction, generated a detailed overview of the extracellular matrix constituents expressed in a second tier of defense to liver injury. PMID:24359594

Threshold detection in an on-off binary communications channel with atmospheric scintillation

NASA Technical Reports Server (NTRS)

Webb, W. E.; Marino, J. T., Jr.

1974-01-01

The optimum detection threshold in an on-off binary optical communications system operating in the presence of atmospheric turbulence was investigated assuming a poisson detection process and log normal scintillation. The dependence of the probability of bit error on log amplitude variance and received signal strength was analyzed and semi-emperical relationships to predict the optimum detection threshold derived. On the basis of this analysis a piecewise linear model for an adaptive threshold detection system is presented. Bit error probabilities for non-optimum threshold detection system were also investigated.

Threshold detection in an on-off binary communications channel with atmospheric scintillation

NASA Technical Reports Server (NTRS)

Webb, W. E.

1975-01-01

The optimum detection threshold in an on-off binary optical communications system operating in the presence of atmospheric turbulence was investigated assuming a poisson detection process and log normal scintillation. The dependence of the probability of bit error on log amplitude variance and received signal strength was analyzed and semi-empirical relationships to predict the optimum detection threshold derived. On the basis of this analysis a piecewise linear model for an adaptive threshold detection system is presented. The bit error probabilities for nonoptimum threshold detection systems were also investigated.

Transistor-based particle detection systems and methods

DOEpatents

Jain, Ankit; Nair, Pradeep R.; Alam, Muhammad Ashraful

2015-06-09

Transistor-based particle detection systems and methods may be configured to detect charged and non-charged particles. Such systems may include a supporting structure contacting a gate of a transistor and separating the gate from a dielectric of the transistor, and the transistor may have a near pull-in bias and a sub-threshold region bias to facilitate particle detection. The transistor may be configured to change current flow through the transistor in response to a change in stiffness of the gate caused by securing of a particle to the gate, and the transistor-based particle detection system may configured to detect the non-charged particle at least from the change in current flow.

Goaf water detection using the grounded electrical source airborne transient electromagnetic system

NASA Astrophysics Data System (ADS)

Li, D.; Ji, Y.; Guan, S.; Wu, Y.; Wang, A.

2017-12-01

To detect the geoelectric characteristic of goaf water, the grounded electrical source airborne transient electromagnetic (GREATEM) system (developed by Jilin University, China) is applied to the goaf water detection since its advantages of considerable prospecting depth, lateral resolution and detection efficiency. For the test of GREATEM system in goaf water detection, an experimental survey was conducted at Qinshui coal mine (Shanxi province, China). After data acquisition, noise reduction and inversion, the resistivity profiles of survey area is presented. The results highly agree the investigation information provided by Shanxi Coal Geology Geophysical Surveying Exploration Institute (China), conforming that the GREATEM system is an effective technique for resistivity detection of goaf water.

Statistical Hypothesis Testing using CNN Features for Synthesis of Adversarial Counterexamples to Human and Object Detection Vision Systems

DOE Office of Scientific and Technical Information (OSTI.GOV)

Raj, Sunny; Jha, Sumit Kumar; Pullum, Laura L.

Validating the correctness of human detection vision systems is crucial for safety applications such as pedestrian collision avoidance in autonomous vehicles. The enormous space of possible inputs to such an intelligent system makes it difficult to design test cases for such systems. In this report, we present our tool MAYA that uses an error model derived from a convolutional neural network (CNN) to explore the space of images similar to a given input image, and then tests the correctness of a given human or object detection system on such perturbed images. We demonstrate the capability of our tool on themore » pre-trained Histogram-of-Oriented-Gradients (HOG) human detection algorithm implemented in the popular OpenCV toolset and the Caffe object detection system pre-trained on the ImageNet benchmark. Our tool may serve as a testing resource for the designers of intelligent human and object detection systems.« less

Factors Influencing Performance of Internet-Based Biosurveillance Systems Used in Epidemic Intelligence for Early Detection of Infectious Diseases Outbreaks

PubMed Central

Barboza, Philippe; Vaillant, Laetitia; Le Strat, Yann; Hartley, David M.; Nelson, Noele P.; Mawudeku, Abla; Madoff, Lawrence C.; Linge, Jens P.; Collier, Nigel; Brownstein, John S.; Astagneau, Pascal

2014-01-01

Background Internet-based biosurveillance systems have been developed to detect health threats using information available on the Internet, but system performance has not been assessed relative to end-user needs and perspectives. Method and Findings Infectious disease events from the French Institute for Public Health Surveillance (InVS) weekly international epidemiological bulletin published in 2010 were used to construct the gold-standard official dataset. Data from six biosurveillance systems were used to detect raw signals (infectious disease events from informal Internet sources): Argus, BioCaster, GPHIN, HealthMap, MedISys and ProMED-mail. Crude detection rates (C-DR), crude sensitivity rates (C-Se) and intrinsic sensitivity rates (I-Se) were calculated from multivariable regressions to evaluate the systems’ performance (events detected compared to the gold-standard) 472 raw signals (Internet disease reports) related to the 86 events included in the gold-standard data set were retrieved from the six systems. 84 events were detected before their publication in the gold-standard. The type of sources utilised by the systems varied significantly (p<0001). I-Se varied significantly from 43% to 71% (p = 0001) whereas other indicators were similar (C-DR: p = 020; C-Se, p = 013). I-Se was significantly associated with individual systems, types of system, languages, regions of occurrence, and types of infectious disease. Conversely, no statistical difference of C-DR was observed after adjustment for other variables. Conclusion Although differences could result from a biosurveillance system's conceptual design, findings suggest that the combined expertise amongst systems enhances early detection performance for detection of infectious diseases. While all systems showed similar early detection performance, systems including human moderation were found to have a 53% higher I-Se (p = 00001) after adjustment for other variables. Overall, the use of moderation, sources, languages, regions of occurrence, and types of cases were found to influence system performance. PMID:24599062

Computer systems for automatic earthquake detection

USGS Publications Warehouse

Stewart, S.W.

1974-01-01

U.S Geological Survey seismologists in Menlo park, California, are utilizing the speed, reliability, and efficiency of minicomputers to monitor seismograph stations and to automatically detect earthquakes. An earthquake detection computer system, believed to be the only one of its kind in operation, automatically reports about 90 percent of all local earthquakes recorded by a network of over 100 central California seismograph stations. The system also monitors the stations for signs of malfunction or abnormal operation. Before the automatic system was put in operation, all of the earthquakes recorded had to be detected by manually searching the records, a time-consuming process. With the automatic detection system, the stations are efficiently monitored continuously. 

Study and realization of an obstacle detection infrared system for automotive use

NASA Astrophysics Data System (ADS)

Alaouiamine, Mohammed

1991-08-01

The main technological options available in the field of obstacle detection are presented. Ultrasound, microwave, and infrared detection systems are reviewed. The reasons for choosing an infrared solution are outlined. The problems involved in developing an obstacle detection system in the near infrared are discussed. Weather condition effects, interference limitations due to multiple onboard sensors, and range detection influence are some of the problems studied. A collimated, mechanically scanned, and pulsed infrared beam is proposed to overcome some of these problems. Performances of a first and second prototype made using this system are presented.

Intrusion Detection in Database Systems

NASA Astrophysics Data System (ADS)

Javidi, Mohammad M.; Sohrabi, Mina; Rafsanjani, Marjan Kuchaki

Data represent today a valuable asset for organizations and companies and must be protected. Ensuring the security and privacy of data assets is a crucial and very difficult problem in our modern networked world. Despite the necessity of protecting information stored in database systems (DBS), existing security models are insufficient to prevent misuse, especially insider abuse by legitimate users. One mechanism to safeguard the information in these databases is to use an intrusion detection system (IDS). The purpose of Intrusion detection in database systems is to detect transactions that access data without permission. In this paper several database Intrusion detection approaches are evaluated.

Development of an assisting detection system for early infarct diagnosis

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sim, K. S.; Nia, M. E.; Ee, C. S.

2015-04-24

In this paper, a detection assisting system for early infarct detection is developed. This new developed method is used to assist the medical practitioners to diagnose infarct from computed tomography images of brain. Using this assisting system, the infarct could be diagnosed at earlier stages. The non-contrast computed tomography (NCCT) brain images are the data set used for this system. Detection module extracts the pixel data from NCCT brain images, and produces the colourized version of images. The proposed method showed great potential in detecting infarct, and helps medical practitioners to make earlier and better diagnoses.

An intelligent control system for failure detection and controller reconfiguration

NASA Technical Reports Server (NTRS)

Biswas, Saroj K.

1994-01-01

We present an architecture of an intelligent restructurable control system to automatically detect failure of system components, assess its impact on system performance and safety, and reconfigure the controller for performance recovery. Fault detection is based on neural network associative memories and pattern classifiers, and is implemented using a multilayer feedforward network. Details of the fault detection network along with simulation results on health monitoring of a dc motor have been presented. Conceptual developments for fault assessment using an expert system and controller reconfiguration using a neural network are outlined.

46 CFR 193.05-1 - Fire detecting, manual alarm, and supervised patrol systems.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 46 Shipping 7 2013-10-01 2013-10-01 false Fire detecting, manual alarm, and supervised patrol...) OCEANOGRAPHIC RESEARCH VESSELS FIRE PROTECTION EQUIPMENT Fire Detecting and Extinguishing Equipment, Where Required § 193.05-1 Fire detecting, manual alarm, and supervised patrol systems. (a) Fire detecting, manual...

46 CFR 193.05-1 - Fire detecting, manual alarm, and supervised patrol systems.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 46 Shipping 7 2012-10-01 2012-10-01 false Fire detecting, manual alarm, and supervised patrol...) OCEANOGRAPHIC RESEARCH VESSELS FIRE PROTECTION EQUIPMENT Fire Detecting and Extinguishing Equipment, Where Required § 193.05-1 Fire detecting, manual alarm, and supervised patrol systems. (a) Fire detecting, manual...

46 CFR 193.05-1 - Fire detecting, manual alarm, and supervised patrol systems.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 7 2011-10-01 2011-10-01 false Fire detecting, manual alarm, and supervised patrol...) OCEANOGRAPHIC RESEARCH VESSELS FIRE PROTECTION EQUIPMENT Fire Detecting and Extinguishing Equipment, Where Required § 193.05-1 Fire detecting, manual alarm, and supervised patrol systems. (a) Fire detecting, manual...

46 CFR 193.05-1 - Fire detecting, manual alarm, and supervised patrol systems.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 46 Shipping 7 2014-10-01 2014-10-01 false Fire detecting, manual alarm, and supervised patrol...) OCEANOGRAPHIC RESEARCH VESSELS FIRE PROTECTION EQUIPMENT Fire Detecting and Extinguishing Equipment, Where Required § 193.05-1 Fire detecting, manual alarm, and supervised patrol systems. (a) Fire detecting, manual...

46 CFR 95.05-1 - Fire detecting, manual alarm, and supervised patrol systems.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 4 2011-10-01 2011-10-01 false Fire detecting, manual alarm, and supervised patrol... AND MISCELLANEOUS VESSELS FIRE PROTECTION EQUIPMENT Fire Detecting and Extinguishing Equipment, Where Required § 95.05-1 Fire detecting, manual alarm, and supervised patrol systems. (a) Fire detecting, manual...

46 CFR 95.05-1 - Fire detecting, manual alarm, and supervised patrol systems.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 4 2010-10-01 2010-10-01 false Fire detecting, manual alarm, and supervised patrol... AND MISCELLANEOUS VESSELS FIRE PROTECTION EQUIPMENT Fire Detecting and Extinguishing Equipment, Where Required § 95.05-1 Fire detecting, manual alarm, and supervised patrol systems. (a) Fire detecting, manual...

46 CFR 193.05-1 - Fire detecting, manual alarm, and supervised patrol systems.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 7 2010-10-01 2010-10-01 false Fire detecting, manual alarm, and supervised patrol...) OCEANOGRAPHIC RESEARCH VESSELS FIRE PROTECTION EQUIPMENT Fire Detecting and Extinguishing Equipment, Where Required § 193.05-1 Fire detecting, manual alarm, and supervised patrol systems. (a) Fire detecting, manual...

46 CFR 95.05-1 - Fire detecting, manual alarm, and supervised patrol systems.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 46 Shipping 4 2012-10-01 2012-10-01 false Fire detecting, manual alarm, and supervised patrol... AND MISCELLANEOUS VESSELS FIRE PROTECTION EQUIPMENT Fire Detecting and Extinguishing Equipment, Where Required § 95.05-1 Fire detecting, manual alarm, and supervised patrol systems. (a) Fire detecting, manual...

Distributed road assessment system

DOEpatents

Beer, N. Reginald; Paglieroni, David W

2014-03-25

A system that detects damage on or below the surface of a paved structure or pavement is provided. A distributed road assessment system includes road assessment pods and a road assessment server. Each road assessment pod includes a ground-penetrating radar antenna array and a detection system that detects road damage from the return signals as the vehicle on which the pod is mounted travels down a road. Each road assessment pod transmits to the road assessment server occurrence information describing each occurrence of road damage that is newly detected on a current scan of a road. The road assessment server maintains a road damage database of occurrence information describing the previously detected occurrences of road damage. After the road assessment server receives occurrence information for newly detected occurrences of road damage for a portion of a road, the road assessment server determines which newly detected occurrences correspond to which previously detected occurrences of road damage.

MicroRNA-29a in Adult Muscle Stem Cells Controls Skeletal Muscle Regeneration During Injury and Exercise Downstream of Fibroblast Growth Factor-2.

PubMed

Galimov, Artur; Merry, Troy L; Luca, Edlira; Rushing, Elisabeth J; Mizbani, Amir; Turcekova, Katarina; Hartung, Angelika; Croce, Carlo M; Ristow, Michael; Krützfeldt, Jan

2016-03-01

The expansion of myogenic progenitors (MPs) in the adult muscle stem cell niche is critical for the regeneration of skeletal muscle. Activation of quiescent MPs depends on the dismantling of the basement membrane and increased access to growth factors such as fibroblast growth factor-2 (FGF2). Here, we demonstrate using microRNA (miRNA) profiling in mouse and human myoblasts that the capacity of FGF2 to stimulate myoblast proliferation is mediated by miR-29a. FGF2 induces miR-29a expression and inhibition of miR-29a using pharmacological or genetic deletion decreases myoblast proliferation. Next generation RNA sequencing from miR-29a knockout myoblasts (Pax7(CE/+) ; miR-29a(flox/flox) ) identified members of the basement membrane as the most abundant miR-29a targets. Using gain- and loss-of-function experiments, we confirm that miR-29a coordinately regulates Fbn1, Lamc1, Nid2, Col4a1, Hspg2 and Sparc in myoblasts in vitro and in MPs in vivo. Induction of FGF2 and miR-29a and downregulation of its target genes precedes muscle regeneration during cardiotoxin (CTX)-induced muscle injury. Importantly, MP-specific tamoxifen-induced deletion of miR-29a in adult skeletal muscle decreased the proliferation and formation of newly formed myofibers during both CTX-induced muscle injury and after a single bout of eccentric exercise. Our results identify a novel miRNA-based checkpoint of the basement membrane in the adult muscle stem cell niche. Strategies targeting miR-29a might provide useful clinical approaches to maintain muscle mass in disease states such as ageing that involve aberrant FGF2 signaling. © 2016 The Authors Stem Cells published by Wiley Periodicals, Inc. on behalf of AlphaMed Press.

Microbial community structure and biodegradation activity of particle-associated bacteria in a coal tar contaminated creek

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jennifer M. DeBruyn; Gary S. Sayler

The Chattanooga Creek Superfund site (Chattanooga, TN) is one of the most polluted waterways in the southeastern U.S. with high polycyclic aromatic hydrocarbon (PAH) concentrations in the sediments. PAHs associate with suspended solids in the water column, and may be redeposited onto the floodplain. These suspended particles represent an interesting but understudied environment for PAH-degrading microbial communities. This study tested the hypotheses that particle-associated bacterial (PAB) communities have genotypic potential (PAH-dioxygenase genes) and activity (naphthalene and pyrene mineralization), and can contribute to natural attenuation of PAHs in Chattanooga Creek. Upstream of the Superfund site, mineralization ranged from 0.2 to 2.0%more » of added {sup 14}C-naphthalene and 0 to 0.1% {sup 14}C-pyrene (after 40 h), with first order biodegradation rate constants (k{sub 1}) ranging from 1.09 to 9.18 x 10{sup -5} h{sup -1} and 0 to 1.13 x 10{sup -6} h{sup -1}, respectively. Mineralization was significantly greater in PAB communities within the contaminated zone, with 11.8 to 31.2% {sup 14}C-naphthalene (k{sup 1} 5.34 to 14.2 x 10-4 h{sup -1}) and 1.3 to 6.6% {sup 14}C-pyrene mineralized (k{sub 1} 2.89 to 15.0 x 10{sup -5} h{sup -1}). Abundances of nagAc (naphthalene dioxygenase) and nidA (pyrene dioxygenase) genes indicated that PAB communities harbored populations with genetic potential for both low- and high-molecular weight PAH degradation, and quantification of Mycobacterium 16S rDNA genes indicated that PAH-degrading mycobacteria are also prevalent in this environment. Phylogenetic comparisons (T-RFLPs) between PAB and sediments indicated these microbial communities were taxonomically distinct, but shared some functional similarities, namely PAH catabolic genotypes, mineralization capabilities, and community structuring along a contamination gradient. 38 refs., 4 figs., 2 tabs.« less

Genetic effects and correlations between production and fertility traits and their dependency on the lactation-stage in Holstein Friesians

PubMed Central

2012-01-01

Background This study focused on the dynamics of genome-wide effects on five milk production and eight fertility traits as well as genetic correlations between the traits. For 2,405 Holstein Friesian bulls, estimated breeding values (EBVs) were used. The production traits were additionally assessed in 10-day intervals over the first 60 lactation days, as this stage is physiologically the most crucial time in milk production. Results SNPs significantly affecting the EBVs of the production traits could be separated into three groups according to the development of the size of allele effects over time: 1) increasing effects for all traits; 2) decreasing effects for all traits; and 3) increasing effects for all traits except fat yield. Most of the significant markers were found within 22 haplotypes spanning on average 135,338 bp. The DGAT1 region showed high density of significant markers, and thus, haplotype blocks. Further functional candidate genes are proposed for haplotype blocks of significant SNPs (KLHL8, SICLEC12, AGPAT6 and NID1). Negative genetic correlations were found between yield and fertility traits, whilst content traits showed positive correlations with some fertility traits. Genetic correlations became stronger with progressing lactation. When correlations were estimated within genotype classes, correlations were on average 0.1 units weaker between production and fertility traits when the yield increasing allele was present in the genotype. Conclusions This study provides insight into the expression of genetic effects during early lactation and suggests possible biological explanations for the presented time-dependent effects. Even though only three markers were found with effects on fertility, the direction of genetic correlations within genotype classes between production and fertility traits suggests that alleles increasing the milk production do not affect fertility in a more negative way compared to the decreasing allele. PMID:23244492

Modular optical detector system

DOEpatents

Horn, Brent A [Livermore, CA; Renzi, Ronald F [Tracy, CA

2006-02-14

A modular optical detector system. The detector system is designed to detect the presence of molecules or molecular species by inducing fluorescence with exciting radiation and detecting the emitted fluorescence. Because the system is capable of accurately detecting and measuring picomolar concentrations it is ideally suited for use with microchemical analysis systems generally and capillary chromatographic systems in particular. By employing a modular design, the detector system provides both the ability to replace various elements of the detector system without requiring extensive realignment or recalibration of the components as well as minimal user interaction with the system. In addition, the modular concept provides for the use and addition of a wide variety of components, including optical elements (lenses and filters), light sources, and detection means, to fit particular needs.

Determination of total sulfur content via sulfur-specific chemiluminescence detection

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kubala, S.W.; Campbell, D.N.; DiSanzo, F.P.

A specially designed system, based upon sulfur-specific chemiluminescence detection (SSCD), was developed to permit the determination of total sulfur content in a variety of samples. This type of detection system possesses several advantages such as excellent linearity and selectivity, low minimum detectable levels, and an equimolar response to various sulfur compounds. This paper will focus on the design and application of a sulfur-specific chemiluminescence detection system for use in determining total sulfur content in gasoline.

Comparative evaluation of Oxoid Signal and BACTEC radiometric blood culture systems for the detection of bacteremia and fungemia

DOE Office of Scientific and Technical Information (OSTI.GOV)

Weinstein, M.P.; Mirrett, S.; Reller, L.B.

1988-05-01

The Oxoid Signal blood culture system is a newly described, innovative method for visually detecting growth of microorganisms. We did 5,999 paired comparisons of equal volumes (10 ml) of blood in the Oxoid Signal and BACTEC radiometric blood culture systems at two university hospitals that use identical methods of obtaining and processing specimens. Overall, more microorganisms were detected in the BACTEC system (P less than 0.001), in particular, streptococci (P less than 0.01), fungi (P less than 0.001), and nonfermentative gram-negative rods, especially Acinetobacter species (P less than 0.001). Trends favoring the BACTEC system for detection of Pseudomonas aeruginosa, Haemophilusmore » species, and Neisseria species were noted. There were no differences in the yield of staphylococci, members of the family Enterobacteriaceae, and anaerobic bacteria. When both systems detected sepsis, the BACTEC did so earlier (P less than 0.001). This advantage was most notable at 24 h (70% of BACTEC positives detected versus 48% of Oxoid positives). The proportion of positives detected after 48 h, however, was similar (BACTEC, 84%; Oxoid, 78%). Revisions in the Oxoid Signal system itself or in the processing of Oxoid bottles appear to be necessary to improve its performance in detecting certain microorganism groups, especially fungi.« less

Advances in developing rapid, reliable and portable detection systems for alcohol.

PubMed

Thungon, Phurpa Dema; Kakoti, Ankana; Ngashangva, Lightson; Goswami, Pranab

2017-11-15

Development of portable, reliable, sensitive, simple, and inexpensive detection system for alcohol has been an instinctive demand not only in traditional brewing, pharmaceutical, food and clinical industries but also in rapidly growing alcohol based fuel industries. Highly sensitive, selective, and reliable alcohol detections are currently amenable typically through the sophisticated instrument based analyses confined mostly to the state-of-art analytical laboratory facilities. With the growing demand of rapid and reliable alcohol detection systems, an all-round attempt has been made over the past decade encompassing various disciplines from basic and engineering sciences. Of late, the research for developing small-scale portable alcohol detection system has been accelerated with the advent of emerging miniaturization techniques, advanced materials and sensing platforms such as lab-on-chip, lab-on-CD, lab-on-paper etc. With these new inter-disciplinary approaches along with the support from the parallel knowledge growth on rapid detection systems being pursued for various targets, the progress on translating the proof-of-concepts to commercially viable and environment friendly portable alcohol detection systems is gaining pace. Here, we summarize the progress made over the years on the alcohol detection systems, with a focus on recent advancement towards developing portable, simple and efficient alcohol sensors. Copyright © 2017 Elsevier B.V. All rights reserved.

Propellant Feed System Leak Detection: Lessons Learned From the Linear Aerospike SR-71 Experiment (LASRE)

NASA Technical Reports Server (NTRS)

Hass, Neal; Mizukami, Masashi; Neal, Bradford A.; St. John, Clinton; Beil, Robert J.; Griffin, Timothy P.

1999-01-01

This paper presents pertinent results and assessment of propellant feed system leak detection as applied to the Linear Aerospike SR-71 Experiment (LASRE) program flown at the NASA Dryden Flight Research Center, Edwards, California. The LASRE was a flight test of an aerospike rocket engine using liquid oxygen and high-pressure gaseous hydrogen as propellants. The flight safety of the crew and the experiment demanded proven technologies and techniques that could detect leaks and assess the integrity of hazardous propellant feed systems. Point source detection and systematic detection were used. Point source detection was adequate for catching gross leakage from components of the propellant feed systems, but insufficient for clearing LASRE to levels of acceptability. Systematic detection, which used high-resolution instrumentation to evaluate the health of the system within a closed volume, provided a better means for assessing leak hazards. Oxygen sensors detected a leak rate of approximately 0.04 cubic inches per second of liquid oxygen. Pressure sensor data revealed speculated cryogenic boiloff through the fittings of the oxygen system, but location of the source(s) was indeterminable. Ultimately, LASRE was cancelled because leak detection techniques were unable to verify that oxygen levels could be maintained below flammability limits.

Combined hostile fire and optics detection

NASA Astrophysics Data System (ADS)

Brännlund, Carl; Tidström, Jonas; Henriksson, Markus; Sjöqvist, Lars

2013-10-01

Snipers and other optically guided weapon systems are serious threats in military operations. We have studied a SWIR (Short Wave Infrared) camera-based system with capability to detect and locate snipers both before and after shot over a large field-of-view. The high frame rate SWIR-camera allows resolution of the temporal profile of muzzle flashes which is the infrared signature associated with the ejection of the bullet from the rifle. The capability to detect and discriminate sniper muzzle flashes with this system has been verified by FOI in earlier studies. In this work we have extended the system by adding a laser channel for optics detection. A laser diode with slit-shaped beam profile is scanned over the camera field-of-view to detect retro reflection from optical sights. The optics detection system has been tested at various distances up to 1.15 km showing the feasibility to detect rifle scopes in full daylight. The high speed camera gives the possibility to discriminate false alarms by analyzing the temporal data. The intensity variation, caused by atmospheric turbulence, enables discrimination of small sights from larger reflectors due to aperture averaging, although the targets only cover a single pixel. It is shown that optics detection can be integrated in combination with muzzle flash detection by adding a scanning rectangular laser slit. The overall optics detection capability by continuous surveillance of a relatively large field-of-view looks promising. This type of multifunctional system may become an important tool to detect snipers before and after shot.

40 CFR 63.7833 - How do I demonstrate continuous compliance with the emission limitations that apply to me?

Code of Federal Regulations, 2010 CFR

2010-07-01

... baghouse equipped with a bag leak detection system, operating and maintaining each bag leak detection... requirements. If you increase or decrease the sensitivity of the bag leak detection system beyond the limits... event of a bag leak detection system alarm or when the hourly average opacity exceeded 5 percent, the...

Deep Recurrent Neural Networks for seizure detection and early seizure detection systems

DOE Office of Scientific and Technical Information (OSTI.GOV)

Talathi, S. S.

Epilepsy is common neurological diseases, affecting about 0.6-0.8 % of world population. Epileptic patients suffer from chronic unprovoked seizures, which can result in broad spectrum of debilitating medical and social consequences. Since seizures, in general, occur infrequently and are unpredictable, automated seizure detection systems are recommended to screen for seizures during long-term electroencephalogram (EEG) recordings. In addition, systems for early seizure detection can lead to the development of new types of intervention systems that are designed to control or shorten the duration of seizure events. In this article, we investigate the utility of recurrent neural networks (RNNs) in designing seizuremore » detection and early seizure detection systems. We propose a deep learning framework via the use of Gated Recurrent Unit (GRU) RNNs for seizure detection. We use publicly available data in order to evaluate our method and demonstrate very promising evaluation results with overall accuracy close to 100 %. We also systematically investigate the application of our method for early seizure warning systems. Our method can detect about 98% of seizure events within the first 5 seconds of the overall epileptic seizure duration.« less

Rapid detection of Bacillus anthracis spores using a super-paramagnetic lateral-flow immunological detection system.

PubMed

Wang, Dian-Bing; Tian, Bo; Zhang, Zhi-Ping; Deng, Jiao-Yu; Cui, Zong-Qiang; Yang, Rui-Fu; Wang, Xu-Ying; Wei, Hong-Ping; Zhang, Xian-En

2013-04-15

There is an urgent need for convenient, sensitive, and specific methods to detect the spores of Bacillus anthracis, the causative agent of anthrax, because of the bioterrorism threat posed by this bacterium. In this study, we firstly develop a super-paramagnetic lateral-flow immunological detection system for B. anthracis spores. This system involves the use of a portable magnetic assay reader, super-paramagnetic iron oxide particles, lateral-flow strips and two different monoclonal antibodies directed against B. anthracis spores. This detection system specifically recognises as few as 400 pure B. anthracis spores in 30 min. This system has a linear range of 4×10³-10⁶ CFU ml⁻¹ and reproducible detection limits of 200 spores mg⁻¹ milk powder and 130 spores mg⁻¹ soil for simulated samples. In addition, this approach shows no obvious cross-reaction with other related Bacillus spores, even at high concentrations, and has no significant dependence on the duration of the storage of the immunological strips. Therefore, this super-paramagnetic lateral-flow immunological detection system is a promising tool for the rapid and sensitive detection of Bacillus anthracis spores under field conditions. Copyright © 2012 Elsevier B.V. All rights reserved.

The Use of Electronic Book Theft Detection Systems in Libraries.

ERIC Educational Resources Information Center

Witt, Thomas B.

1996-01-01

Although electronic book theft detection systems can be a deterrent to library material theft, no electronic system is foolproof, and a total security program is necessary to ensure collection security. Describes how book theft detection systems work, their effectiveness, and the problems inherent in technology. A total security program considers…

Evaluating Fluorscence-Based Metrics for Early Detection of ...

EPA Pesticide Factsheets

Summary: This paper discusses the results of an ongoing Water Research Foundation project on developing a fluorescence sensor system for early detection of distribution system nitrification Summary: This paper discusses the results of an ongoing Water Research Foundation project on developing a fluorescence sensor system for early detection of distribution system nitrification

Real-time distributed fiber optic sensor for security systems: Performance, event classification and nuisance mitigation

NASA Astrophysics Data System (ADS)

Mahmoud, Seedahmed S.; Visagathilagar, Yuvaraja; Katsifolis, Jim

2012-09-01

The success of any perimeter intrusion detection system depends on three important performance parameters: the probability of detection (POD), the nuisance alarm rate (NAR), and the false alarm rate (FAR). The most fundamental parameter, POD, is normally related to a number of factors such as the event of interest, the sensitivity of the sensor, the installation quality of the system, and the reliability of the sensing equipment. The suppression of nuisance alarms without degrading sensitivity in fiber optic intrusion detection systems is key to maintaining acceptable performance. Signal processing algorithms that maintain the POD and eliminate nuisance alarms are crucial for achieving this. In this paper, a robust event classification system using supervised neural networks together with a level crossings (LCs) based feature extraction algorithm is presented for the detection and recognition of intrusion and non-intrusion events in a fence-based fiber-optic intrusion detection system. A level crossings algorithm is also used with a dynamic threshold to suppress torrential rain-induced nuisance alarms in a fence system. Results show that rain-induced nuisance alarms can be suppressed for rainfall rates in excess of 100 mm/hr with the simultaneous detection of intrusion events. The use of a level crossing based detection and novel classification algorithm is also presented for a buried pipeline fiber optic intrusion detection system for the suppression of nuisance events and discrimination of intrusion events. The sensor employed for both types of systems is a distributed bidirectional fiber-optic Mach-Zehnder (MZ) interferometer.

Improved dual-loop detection system for collecting real-time truck data

DOT National Transportation Integrated Search

2005-02-01

The WSDOTs dual-loop detectors capability of measuring vehicle lengths makes the dual-loop detection system a potential real-time truck data source for freight movement study. However, a previous study found the WSDOT dual-loop detection system...

A study on obstacle detection method of the frontal view using a camera on highway

NASA Astrophysics Data System (ADS)

Nguyen, Van-Quang; Park, Jeonghyeon; Seo, Changjun; Kim, Heungseob; Boo, Kwangsuck

2018-03-01

In this work, we introduce an approach to detect vehicles for driver assistance, or warning system. For driver assistance system, it must detect both lanes (left and right side lane), and discover vehicles ahead of the test vehicle. Therefore, in this study, we use a camera, it is installed on the windscreen of the test vehicle. Images from the camera are used to detect three lanes, and detect multiple vehicles. In lane detection, line detection and vanishing point estimation are used. For the vehicle detection, we combine the horizontal and vertical edge detection, the horizontal edge is used to detect the vehicle candidates, and then the vertical edge detection is used to verify the vehicle candidates. The proposed algorithm works with of 480 × 640 image frame resolution. The system was tested on the highway in Korea.

A miniaturised image based fluorescence detection system for point-of-care-testing of cocaine abuse

NASA Astrophysics Data System (ADS)

Walczak, Rafał; Krüger, Jan; Moynihan, Shane

2015-08-01

In this paper, we describe a miniaturised image-based fluorescence detection system and demonstrate its viability as a highly sensitive tool for point-of-care-analysis of drugs of abuse in human sweat with a focus on monitor individuals for drugs of abuse. Investigations of miniaturised and low power optoelectronic configurations and methodologies for real-time image analysis were successfully carried out. The miniaturised fluorescence detection system was validated against a reference detection system under controlled laboratory conditions by analysing spiked sweat samples in dip stick and then strip with sample pad. As a result of the validation studies, a 1 ng mL-1 limit of detection of cocaine in sweat and full agreement of test results with the reference detection system can be reported. Results of the investigations open the way towards a detection system that integrates a hand-held fluorescence reader and a wearable skinpatch, and which can collect and in situ analyse sweat for the presence of cocaine at any point for up to tenths hours.

40 CFR 265.19 - Construction quality assurance program.

Code of Federal Regulations, 2012 CFR

2012-07-01

...) Geomembranes (flexible membrane liners); (v) Leachate collection and removal systems and leak detection systems..., leachate collection and removal system, leak detection system, and final cover system, according to permit...

40 CFR 265.19 - Construction quality assurance program.

Code of Federal Regulations, 2014 CFR

2014-07-01

...) Geomembranes (flexible membrane liners); (v) Leachate collection and removal systems and leak detection systems..., leachate collection and removal system, leak detection system, and final cover system, according to permit...

40 CFR 265.19 - Construction quality assurance program.

Code of Federal Regulations, 2011 CFR

2011-07-01

...) Geomembranes (flexible membrane liners); (v) Leachate collection and removal systems and leak detection systems..., leachate collection and removal system, leak detection system, and final cover system, according to permit...

The architecture of a network level intrusion detection system

DOE Office of Scientific and Technical Information (OSTI.GOV)

Heady, R.; Luger, G.; Maccabe, A.

1990-08-15

This paper presents the preliminary architecture of a network level intrusion detection system. The proposed system will monitor base level information in network packets (source, destination, packet size, and time), learning the normal patterns and announcing anomalies as they occur. The goal of this research is to determine the applicability of current intrusion detection technology to the detection of network level intrusions. In particular, the authors are investigating the possibility of using this technology to detect and react to worm programs.

Combating Terrorism: 2005 TSWG Review

DTIC Science & Technology

2005-01-01

will have a greater capacity and will be more compact than existing kits. Advanced Hybrid Chemical Detection System Existing sensor systems to...detect chemical agents are either very expensive or provide limited sensitivity and response. Avir, LLC designed and built a hybrid detection system for... hybrid system at an equally low cost. The system has undergone live-agent testing and environmental testing. Extended field-testing in select buildings

Fuzzy Kernel k-Medoids algorithm for anomaly detection problems

NASA Astrophysics Data System (ADS)

Rustam, Z.; Talita, A. S.

2017-07-01

Intrusion Detection System (IDS) is an essential part of security systems to strengthen the security of information systems. IDS can be used to detect the abuse by intruders who try to get into the network system in order to access and utilize the available data sources in the system. There are two approaches of IDS, Misuse Detection and Anomaly Detection (behavior-based intrusion detection). Fuzzy clustering-based methods have been widely used to solve Anomaly Detection problems. Other than using fuzzy membership concept to determine the object to a cluster, other approaches as in combining fuzzy and possibilistic membership or feature-weighted based methods are also used. We propose Fuzzy Kernel k-Medoids that combining fuzzy and possibilistic membership as a powerful method to solve anomaly detection problem since on numerical experiment it is able to classify IDS benchmark data into five different classes simultaneously. We classify IDS benchmark data KDDCup'99 data set into five different classes simultaneously with the best performance was achieved by using 30 % of training data with clustering accuracy reached 90.28 percent.

Detection of Landmines by Neutron Backscattering: Effects of Soil Moisture on the Detection System

DOE Office of Scientific and Technical Information (OSTI.GOV)

Baysoy, D. Y.; Subasi, M.

2010-01-21

Detection of buried land mines by using neutron backscattering technique (NBS) is a well established method. It depends on detecting a hydrogen anomaly in dry soil. Since a landmine and its plastic casing contain much more hydrogen atoms than the dry soil, this anomaly can be detected by observing a rise in the number of neutrons moderated to thermal or epithermal energy. But, the presence of moisture in the soil limits the effectiveness of the measurements. In this work, a landmine detection system using the NBS technique was designed. A series of Monte Carlo calculations was carried out to determinemore » the limits of the system due to the moisture content of the soil. In the simulations, an isotropic fast neutron source ({sup 252}Cf, 100 mug) and a neutron detection system which consists of five {sup 3}He detectors were used in a practicable geometry. In order to see the effects of soil moisture on the efficiency of the detection system, soils with different water contents were tested.« less

Protecting against cyber threats in networked information systems

NASA Astrophysics Data System (ADS)

Ertoz, Levent; Lazarevic, Aleksandar; Eilertson, Eric; Tan, Pang-Ning; Dokas, Paul; Kumar, Vipin; Srivastava, Jaideep

2003-07-01

This paper provides an overview of our efforts in detecting cyber attacks in networked information systems. Traditional signature based techniques for detecting cyber attacks can only detect previously known intrusions and are useless against novel attacks and emerging threats. Our current research at the University of Minnesota is focused on developing data mining techniques to automatically detect attacks against computer networks and systems. This research is being conducted as a part of MINDS (Minnesota Intrusion Detection System) project at the University of Minnesota. Experimental results on live network traffic at the University of Minnesota show that the new techniques show great promise in detecting novel intrusions. In particular, during the past few months our techniques have been successful in automatically identifying several novel intrusions that could not be detected using state-of-the-art tools such as SNORT.

Sensor Failure Detection of FASSIP System using Principal Component Analysis

NASA Astrophysics Data System (ADS)

Sudarno; Juarsa, Mulya; Santosa, Kussigit; Deswandri; Sunaryo, Geni Rina

2018-02-01

In the nuclear reactor accident of Fukushima Daiichi in Japan, the damages of core and pressure vessel were caused by the failure of its active cooling system (diesel generator was inundated by tsunami). Thus researches on passive cooling system for Nuclear Power Plant are performed to improve the safety aspects of nuclear reactors. The FASSIP system (Passive System Simulation Facility) is an installation used to study the characteristics of passive cooling systems at nuclear power plants. The accuracy of sensor measurement of FASSIP system is essential, because as the basis for determining the characteristics of a passive cooling system. In this research, a sensor failure detection method for FASSIP system is developed, so the indication of sensor failures can be detected early. The method used is Principal Component Analysis (PCA) to reduce the dimension of the sensor, with the Squarred Prediction Error (SPE) and statistic Hotteling criteria for detecting sensor failure indication. The results shows that PCA method is capable to detect the occurrence of a failure at any sensor.

Detection of nuclei in 4D Nomarski DIC microscope images of early Caenorhabditis elegans embryos using local image entropy and object tracking

PubMed Central

Hamahashi, Shugo; Onami, Shuichi; Kitano, Hiroaki

2005-01-01

Background The ability to detect nuclei in embryos is essential for studying the development of multicellular organisms. A system of automated nuclear detection has already been tested on a set of four-dimensional (4D) Nomarski differential interference contrast (DIC) microscope images of Caenorhabditis elegans embryos. However, the system needed laborious hand-tuning of its parameters every time a new image set was used. It could not detect nuclei in the process of cell division, and could detect nuclei only from the two- to eight-cell stages. Results We developed a system that automates the detection of nuclei in a set of 4D DIC microscope images of C. elegans embryos. Local image entropy is used to produce regions of the images that have the image texture of the nucleus. From these regions, those that actually detect nuclei are manually selected at the first and last time points of the image set, and an object-tracking algorithm then selects regions that detect nuclei in between the first and last time points. The use of local image entropy makes the system applicable to multiple image sets without the need to change its parameter values. The use of an object-tracking algorithm enables the system to detect nuclei in the process of cell division. The system detected nuclei with high sensitivity and specificity from the one- to 24-cell stages. Conclusion A combination of local image entropy and an object-tracking algorithm enabled highly objective and productive detection of nuclei in a set of 4D DIC microscope images of C. elegans embryos. The system will facilitate genomic and computational analyses of C. elegans embryos. PMID:15910690

Upconverting nanoparticles for optimizing scintillator based detection systems

DOEpatents

Kross, Brian; McKisson, John E; McKisson, John; Weisenberger, Andrew; Xi, Wenze; Zom, Carl

2013-09-17

An upconverting device for a scintillation detection system is provided. The detection system comprises a scintillator material, a sensor, a light transmission path between the scintillator material and the sensor, and a plurality of upconverting nanoparticles particles positioned in the light transmission path.

Edge detection based on computational ghost imaging with structured illuminations

NASA Astrophysics Data System (ADS)

Yuan, Sheng; Xiang, Dong; Liu, Xuemei; Zhou, Xin; Bing, Pibin

2018-03-01

Edge detection is one of the most important tools to recognize the features of an object. In this paper, we propose an optical edge detection method based on computational ghost imaging (CGI) with structured illuminations which are generated by an interference system. The structured intensity patterns are designed to make the edge of an object be directly imaged from detected data in CGI. This edge detection method can extract the boundaries for both binary and grayscale objects in any direction at one time. We also numerically test the influence of distance deviations in the interference system on edge extraction, i.e., the tolerance of the optical edge detection system to distance deviation. Hopefully, it may provide a guideline for scholars to build an experimental system.

Analysis of Tyman green detection system based on polarization interference

NASA Astrophysics Data System (ADS)

Huang, Yaolin; Wang, Min; Shao, Xiaoping; Kou, Yuanfeng

2018-02-01

The optical surface deviation of the lens can directly affect the quality of the optical system.In order to effectively and accurately detect the surface shape, an optical surface on-line detection system based on polarization interference technology is designed and developed. The system is based on Tyman-Green interference optical path, join the polarization interference measuring technology. Based on the theoretical derivation of the optical path and the ZEMAX software simulation, the experimental optical path is constructed. The parallel light is used to detect the concave lens. The parallel light is used as the light source, the size of the polarization splitting prism, detection radius of curvature, the relations between and among the size of the lens aperture, a detection range is given.

Topological characterization and early detection of bifurcations and chaos in complex systems using persistent homology.

PubMed

Mittal, Khushboo; Gupta, Shalabh

2017-05-01

Early detection of bifurcations and chaos and understanding their topological characteristics are essential for safe and reliable operation of various electrical, chemical, physical, and industrial processes. However, the presence of non-linearity and high-dimensionality in system behavior makes this analysis a challenging task. The existing methods for dynamical system analysis provide useful tools for anomaly detection (e.g., Bendixson-Dulac and Poincare-Bendixson criteria can detect the presence of limit cycles); however, they do not provide a detailed topological understanding about system evolution during bifurcations and chaos, such as the changes in the number of subcycles and their positions, lifetimes, and sizes. This paper addresses this research gap by using topological data analysis as a tool to study system evolution and develop a mathematical framework for detecting the topological changes in the underlying system using persistent homology. Using the proposed technique, topological features (e.g., number of relevant k-dimensional holes, etc.) are extracted from nonlinear time series data which are useful for deeper analysis of the system behavior and early detection of bifurcations and chaos. When applied to a Logistic map, a Duffing oscillator, and a real life Op-amp based Jerk circuit, these features are shown to accurately characterize the system dynamics and detect the onset of chaos.

An explosives detection system for airline security using coherent x-ray scattering technology

NASA Astrophysics Data System (ADS)

Madden, Robert W.; Mahdavieh, Jacob; Smith, Richard C.; Subramanian, Ravi

2008-08-01

L-3 Communications Security and Detection Systems (SDS) has developed a new system for automated alarm resolution in airline baggage Explosive Detection Systems (EDS) based on coherent x-ray scattering spectroscopy. The capabilities of the system were demonstrated in tests with concealed explosives at the Transportation Security Laboratory and airline passenger baggage at Orlando International Airport. The system uses x-ray image information to identify suspicious objects and performs targeted diffraction measurements to classify them. This extra layer of detection capability affords a significant reduction in the rate of false alarm objects that must presently be resolved by opening passenger bags for hand inspection.

Distribution System Audits, Leak Detection, and Repair: Kirtland Air Force Base Leak Detection and Repair Program

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

Water Best Management Practice #3 Fact Seet: Outlines how a leak detection and repair program helped Kirtland Air Force Base perform distribution system audits, leak detection, and repair to conserve water site-wide.

Thermal background noise limitations

NASA Technical Reports Server (NTRS)

Gulkis, S.

1982-01-01

Modern detection systems are increasingly limited in sensitivity by the background thermal photons which enter the receiving system. Expressions for the fluctuations of detected thermal radiation are derived. Incoherent and heterodyne detection processes are considered. References to the subject of photon detection statistics are given.

DOE Office of Scientific and Technical Information (OSTI.GOV)

McCann, D.; White, D.

This paper reports on a smart alarm system installed on a number of offshore rigs and one land rig which can detect kicks more quickly than conventional systems. This rapid kick detection improves rig safety because the smaller the detected influx, the easier it is to control the well. The extensive computerized monitoring system helps drilling personnel detect fluid influxes and fluid losses before the changes in flow would normally be apparent.

Feasibility studies on explosive detection and homeland security applications using a neutron and x-ray combined computed tomography system

NASA Astrophysics Data System (ADS)

Sinha, V.; Srivastava, A.; Lee, H. K.; Liu, X.

2013-05-01

The successful creation and operation of a neutron and X-ray combined computed tomography (NXCT) system has been demonstrated by researchers at the Missouri University of Science and Technology. The NXCT system has numerous applications in the field of material characterization and object identification in materials with a mixture of atomic numbers represented. Presently, the feasibility studies have been performed for explosive detection and homeland security applications, particularly in concealed material detection and determination of the light atomic number materials. These materials cannot be detected using traditional X-ray imaging. The new system has the capability to provide complete structural and compositional information due to the complementary nature of X-ray and neutron interactions with materials. The design of the NXCT system facilitates simultaneous and instantaneous imaging operation, promising enhanced detection capabilities of explosive materials, low atomic number materials and illicit materials for homeland security applications. In addition, a sample positioning system allowing the user to remotely and automatically manipulate the sample makes the system viable for commercial applications. Several explosives and weapon simulants have been imaged and the results are provided. The fusion algorithms which combine the data from the neutron and X-ray imaging produce superior images. This paper is a compete overview of the NXCT system for feasibility studies of explosive detection and homeland security applications. The design of the system, operation, algorithm development, and detection schemes are provided. This is the first combined neutron and X-ray computed tomography system in operation. Furthermore, the method of fusing neutron and X-ray images together is a new approach which provides high contrast images of the desired object. The system could serve as a standardized tool in nondestructive testing of many applications, especially in explosives detection and homeland security research.

Flat Surface Damage Detection System (FSDDS)

NASA Technical Reports Server (NTRS)

Williams, Martha; Lewis, Mark; Gibson, Tracy; Lane, John; Medelius, Pedro; Snyder, Sarah; Ciarlariello, Dan; Parks, Steve; Carrejo, Danny; Rojdev, Kristina

2013-01-01

The Flat Surface Damage Detection system (FSDDS} is a sensory system that is capable of detecting impact damages to surfaces utilizing a novel sensor system. This system will provide the ability to monitor the integrity of an inflatable habitat during in situ system health monitoring. The system consists of three main custom designed subsystems: the multi-layer sensing panel, the embedded monitoring system, and the graphical user interface (GUI). The GUI LABVIEW software uses a custom developed damage detection algorithm to determine the damage location based on the sequence of broken sensing lines. It estimates the damage size, the maximum depth, and plots the damage location on a graph. Successfully demonstrated as a stand alone technology during 2011 D-RATS. Software modification also allowed for communication with HDU avionics crew display which was demonstrated remotely (KSC to JSC} during 2012 integration testing. Integrated FSDDS system and stand alone multi-panel systems were demonstrated remotely and at JSC, Mission Operations Test using Space Network Research Federation (SNRF} network in 2012. FY13, FSDDS multi-panel integration with JSC and SNRF network Technology can allow for integration with other complementary damage detection systems.

Robust Fault Detection for Switched Fuzzy Systems With Unknown Input.

PubMed

Han, Jian; Zhang, Huaguang; Wang, Yingchun; Sun, Xun

2017-10-03

This paper investigates the fault detection problem for a class of switched nonlinear systems in the T-S fuzzy framework. The unknown input is considered in the systems. A novel fault detection unknown input observer design method is proposed. Based on the proposed observer, the unknown input can be removed from the fault detection residual. The weighted H∞ performance level is considered to ensure the robustness. In addition, the weighted H₋ performance level is introduced, which can increase the sensibility of the proposed detection method. To verify the proposed scheme, a numerical simulation example and an electromechanical system simulation example are provided at the end of this paper.

A universal DNA-based protein detection system.

PubMed

Tran, Thua N N; Cui, Jinhui; Hartman, Mark R; Peng, Songming; Funabashi, Hisakage; Duan, Faping; Yang, Dayong; March, John C; Lis, John T; Cui, Haixin; Luo, Dan

2013-09-25

Protein immune detection requires secondary antibodies which must be carefully selected in order to avoid interspecies cross-reactivity, and is therefore restricted by the limited availability of primary/secondary antibody pairs. Here we present a versatile DNA-based protein detection system using a universal adapter to interface between IgG antibodies and DNA-modified reporter molecules. As a demonstration of this capability, we successfully used DNA nano-barcodes, quantum dots, and horseradish peroxidase enzyme to detect multiple proteins using our DNA-based labeling system. Our system not only eliminates secondary antibodies but also serves as a novel method platform for protein detection with modularity, high capacity, and multiplexed capability.

A Universal DNA-Based Protein Detection System

PubMed Central

Tran, Thua N. N.; Cui, Jinhui; Hartman, Mark R.; Peng, Songming; Funabashi, Hisakage; Duan, Faping; Yang, Dayong; March, John C.; Lis, John T.; Cui, Haixin; Luo, Dan

2014-01-01

Protein immune detection requires secondary antibodies which must be carefully selected in order to avoid interspecies cross-reactivity, and is therefore restricted by the limited availability of primary/secondary antibody pairs. Here we present a versatile DNA-based protein detection system using a universal adapter to interface between IgG antibodies and DNA-modified reporter molecules. As a demonstration of this capability, we successfully used DNA nano-barcodes, quantum dots, and horseradish peroxidase enzyme to detect multiple proteins using our DNA-based labeling system. Our system not only eliminates secondary antibodies but also serves as a novel method platform for protein detection with modularity, high capacity, and multiplexed capability. PMID:23978265

21 CFR 884.2980 - Telethermographic system.

Code of Federal Regulations, 2010 CFR

2010-04-01

... screening for detection of breast cancer or other uses—(1) Identification. A telethermographic system for adjunctive diagnostic screening for detection of breast cancer or other uses is an electrically powered... system intended for use alone in diagnostic screening for detection of breast cancer or other uses—(1...

21 CFR 884.2980 - Telethermographic system.

Code of Federal Regulations, 2011 CFR

2011-04-01

... screening for detection of breast cancer or other uses—(1) Identification. A telethermographic system for adjunctive diagnostic screening for detection of breast cancer or other uses is an electrically powered... system intended for use alone in diagnostic screening for detection of breast cancer or other uses—(1...

A dual-mode generalized likelihood ratio approach to self-reorganizing digital flight control system design

NASA Technical Reports Server (NTRS)

Bueno, R.; Chow, E.; Gershwin, S. B.; Willsky, A. S.

1975-01-01

The research is reported on the problems of failure detection and reliable system design for digital aircraft control systems. Failure modes, cross detection probability, wrong time detection, application of performance tools, and the GLR computer package are discussed.

21 CFR 884.2980 - Telethermographic system.

Code of Federal Regulations, 2012 CFR

2012-04-01

... screening for detection of breast cancer or other uses—(1) Identification. A telethermographic system for adjunctive diagnostic screening for detection of breast cancer or other uses is an electrically powered... system intended for use alone in diagnostic screening for detection of breast cancer or other uses—(1...

21 CFR 884.2980 - Telethermographic system.

Code of Federal Regulations, 2014 CFR

2014-04-01

... screening for detection of breast cancer or other uses—(1) Identification. A telethermographic system for adjunctive diagnostic screening for detection of breast cancer or other uses is an electrically powered... system intended for use alone in diagnostic screening for detection of breast cancer or other uses—(1...

21 CFR 884.2980 - Telethermographic system.

Code of Federal Regulations, 2013 CFR

2013-04-01

... screening for detection of breast cancer or other uses—(1) Identification. A telethermographic system for adjunctive diagnostic screening for detection of breast cancer or other uses is an electrically powered... system intended for use alone in diagnostic screening for detection of breast cancer or other uses—(1...

Hardware Evaluation Of Heavy Truck Side And Rear Object Detection Systems

DOT National Transportation Integrated Search

1995-01-01

This paper focuses on two types of electronics-based object detection systems for heavy truck applications: those sensing the presence of objects to the rear of the vehicle (referred to as Rear Object Detection Systems, or RODS) and those sensing the...

A Sensor System for Detection of Hull Surface Defects

PubMed Central

Navarro, Pedro; Iborra, Andrés; Fernández, Carlos; Sánchez, Pedro; Suardíaz, Juan

2010-01-01

This paper presents a sensor system for detecting defects in ship hull surfaces. The sensor was developed to enable a robotic system to perform grit blasting operations on ship hulls. To achieve this, the proposed sensor system captures images with the help of a camera and processes them in real time using a new defect detection method based on thresholding techniques. What makes this method different is its efficiency in the automatic detection of defects from images recorded in variable lighting conditions. The sensor system was tested under real conditions at a Spanish shipyard, with excellent results. PMID:22163590

Study to develop improved methods to detect leakage in fluid systems, phase 2

NASA Technical Reports Server (NTRS)

Janus, J. C.; Cimerman, I.

1971-01-01

An ultrasonic contact sensor engineering prototype leak detection system was developed and its capabilities under cryogenic operations demonstrated. The results from tests indicate that the transducer performed well on liquid hydrogen plumbing, that flow and valve actuation could be monitored, and that the phase change from gaseous to liquid hydrogen could be detected by the externally mounted transducers. Tests also demonstrate the ability of the system to detect internal leaks past valve seats and to function as a flow meter. Such a system demonstrates that it is not necessary to break into welded systems to locate internal leaks.

Quality detection system and method of micro-accessory based on microscopic vision

NASA Astrophysics Data System (ADS)

Li, Dongjie; Wang, Shiwei; Fu, Yu

2017-10-01

Considering that the traditional manual detection of micro-accessory has some problems, such as heavy workload, low efficiency and large artificial error, a kind of quality inspection system of micro-accessory has been designed. Micro-vision technology has been used to inspect quality, which optimizes the structure of the detection system. The stepper motor is used to drive the rotating micro-platform to transfer quarantine device and the microscopic vision system is applied to get graphic information of micro-accessory. The methods of image processing and pattern matching, the variable scale Sobel differential edge detection algorithm and the improved Zernike moments sub-pixel edge detection algorithm are combined in the system in order to achieve a more detailed and accurate edge of the defect detection. The grade at the edge of the complex signal can be achieved accurately by extracting through the proposed system, and then it can distinguish the qualified products and unqualified products with high precision recognition.

Performance analysis of a multispectral system for mine detection in the littoral zone

NASA Astrophysics Data System (ADS)

Hargrove, John T.; Louchard, Eric

2004-09-01

Science & Technology International (STI) has developed, under contract with the Office of Naval Research, a system of multispectral airborne sensors and processing algorithms capable of detecting mine-like objects in the surf zone. STI has used this system to detect mine-like objects in a littoral environment as part of blind tests at Kaneohe Marine Corps Base Hawaii, and Panama City, Florida. The airborne and ground subsystems are described. The detection algorithm is graphically illustrated. We report on the performance of the system configured to operate without a human in the loop. A subsurface (underwater bottom proud mine in the surf zone and moored mine in shallow water) mine detection capability is demonstrated in the surf zone, and in shallow water with wave spillage and foam. Our analysis demonstrates that this STI-developed multispectral airborne mine detection system provides a technical foundation for a viable mine counter-measures system for use prior to an amphibious assault.

Optical fiber strain sensor for application in intelligent intruder detection systems

NASA Astrophysics Data System (ADS)

Stańczyk, Tomasz; Tenderenda, Tadeusz; Szostkiewicz, Lukasz; Bienkowska, Beata; Kunicki, Daniel; Murawski, Michal; Mergo, Pawel; Nasilowski, Tomasz

2017-10-01

Nowadays technology allows to create highly effective Intruder Detection Systems (IDS), that are able to detect the presence of an intruder within a defined area. In such systems the best performance can be achieved by combining different detection techniques in one system. One group of devices that can be applied in an IDS, are devices based on Fiber Optic Sensors (FOS). The FOS benefits from numerous advantages of optical fibers like: small size, light weight or high sensitivity. In this work we present a novel Microstructured Optical Fiber (MOF) characterized by increased strain sensitivity dedicated to distributed acoustic sensing for intelligent intruder detection systems. By designing the MOF with large air holes in close proximity to a fiber core, we increased the effective refractive index sensitivity to longitudinal strain. The presented fiber can be easily integrated in a floor system in order to detect any movement in the investigated area. We believe that sensors, based on the presented MOF, due to its numerous advantages, can find application in intelligent IDS.

Setting up a mobile Lidar (DIAL) system for detecting chemical warfare agents

NASA Astrophysics Data System (ADS)

Kavosh Tehrani, M.; Mohammad, M. Malek; Jaafari, E.; Mobashery, A.

2015-03-01

The mobile light detection and ranging DIAL system of Malek Ashtar University of Technology has been developed for the detection of chemical warfare agents whose absorption wavelengths are in the range of 9.2-10.8 μm tunable CO2 lasers of the system. In this paper, this system is first described and then ammonia detection is analyzed experimentally. Also, experimental results of detecting a sarin agent simulant, dimethyl-methyl phosphonate (DMMP), are presented. The power levels received from different ranges to detect specific concentrations of NH3 and DMMP have been measured and debated. The primary test results with a 150 ns clipped pulse width by passive pinhole plasma shutter indicate that the system is capable of monitoring several species of pollutants in the range of about 1 km, with a 20 m spatial and 2 min temporal resolution.

Location precision analysis of stereo thermal anti-sniper detection system

NASA Astrophysics Data System (ADS)

He, Yuqing; Lu, Ya; Zhang, Xiaoyan; Jin, Weiqi

2012-06-01

Anti-sniper detection devices are the urgent requirement in modern warfare. The precision of the anti-sniper detection system is especially important. This paper discusses the location precision analysis of the anti-sniper detection system based on the dual-thermal imaging system. It mainly discusses the following two aspects which produce the error: the digital quantitative effects of the camera; effect of estimating the coordinate of bullet trajectory according to the infrared images in the process of image matching. The formula of the error analysis is deduced according to the method of stereovision model and digital quantitative effects of the camera. From this, we can get the relationship of the detecting accuracy corresponding to the system's parameters. The analysis in this paper provides the theory basis for the error compensation algorithms which are put forward to improve the accuracy of 3D reconstruction of the bullet trajectory in the anti-sniper detection devices.

Particle detection systems and methods

DOEpatents

Morris, Christopher L.; Makela, Mark F.

2010-05-11

Techniques, apparatus and systems for detecting particles such as muons and neutrons. In one implementation, a particle detection system employs a plurality of drift cells, which can be for example sealed gas-filled drift tubes, arranged on sides of a volume to be scanned to track incoming and outgoing charged particles, such as cosmic ray-produced muons. The drift cells can include a neutron sensitive medium to enable concurrent counting of neutrons. The system can selectively detect devices or materials, such as iron, lead, gold, uranium, plutonium, and/or tungsten, occupying the volume from multiple scattering of the charged particles passing through the volume and can concurrently detect any unshielded neutron sources occupying the volume from neutrons emitted therefrom. If necessary, the drift cells can be used to also detect gamma rays. The system can be employed to inspect occupied vehicles at border crossings for nuclear threat objects.

Electrochemical detection for microscale analytical systems: a review.

PubMed

Wang, Joseph

2002-02-11

As the field of chip-based microscale systems continues its rapid growth, there are urgent needs for developing compatible detection modes. Electrochemistry detection offers considerable promise for such microfluidic systems, with features that include remarkable sensitivity, inherent miniaturization and portability, independence of optical path length or sample turbidity, low cost, low-power requirements and high compatibility with advanced micromachining and microfabrication technologies. This paper highlights recent advances, directions and key strategies in controlled-potential electrochemical detectors for miniaturized analytical systems. Subjects covered include the design and integration of the electrochemical detection system, its requirements and operational principles, common electrode materials, derivatization reactions, electrical-field decouplers, typical applications and future prospects. It is expected that electrochemical detection will become a powerful tool for microscale analytical systems and will facilitate the creation of truly portable (and possibly disposable) devices.

A deep-learning based automatic pulmonary nodule detection system

NASA Astrophysics Data System (ADS)

Zhao, Yiyuan; Zhao, Liang; Yan, Zhennan; Wolf, Matthias; Zhan, Yiqiang

2018-02-01

Lung cancer is the deadliest cancer worldwide. Early detection of lung cancer is a promising way to lower the risk of dying. Accurate pulmonary nodule detection in computed tomography (CT) images is crucial for early diagnosis of lung cancer. The development of computer-aided detection (CAD) system of pulmonary nodules contributes to making the CT analysis more accurate and with more efficiency. Recent studies from other groups have been focusing on lung cancer diagnosis CAD system by detecting medium to large nodules. However, to fully investigate the relevance between nodule features and cancer diagnosis, a CAD that is capable of detecting nodules with all sizes is needed. In this paper, we present a deep-learning based automatic all size pulmonary nodule detection system by cascading two artificial neural networks. We firstly use a U-net like 3D network to generate nodule candidates from CT images. Then, we use another 3D neural network to refine the locations of the nodule candidates generated from the previous subsystem. With the second sub-system, we bring the nodule candidates closer to the center of the ground truth nodule locations. We evaluate our system on a public CT dataset provided by the Lung Nodule Analysis (LUNA) 2016 grand challenge. The performance on the testing dataset shows that our system achieves 90% sensitivity with an average of 4 false positives per scan. This indicates that our system can be an aid for automatic nodule detection, which is beneficial for lung cancer diagnosis.

Rapid Identification of Key Pathogens in Wound Infection by Molecular Means

DTIC Science & Technology

2006-01-01

diagnosis and monitoring of infectious diseases [4]. Rapid diagnosis can be achieved by the direct detection of characteristic bacterial genes in clinical... System ABI PRISM® 7500 Sequence Detection System (Applied Biosystems, Foster City, Calif.) was purchased, set up and standardized. This system ...integrated system for real-time detection of PCR. The system includes a built-in thermal cycler, a laser to induce fluorescence, CCD (charge-coupled device

[System design of open-path natural gas leakage detection based on Fresnel lens].

PubMed

Xia, Hui; Liu, Wen-Qing; Zhang, Yu-Jun; Kan, Rui-Feng; Cui, Yi-Ben; Wang, Min; He, Ying; Cui, Xiao-Juan; Ruan, Jun; Geng, Hui

2009-03-01

Based on the technology of tunable diode laser absorption spectroscopy (TDLAS) in conjunction with second harmonic wave detection, a long open-path TDLAS system using a 1.65 microm InGaAsP distributed feedback laser was developed, which is used for detecting pipeline leakage. In this system, a high cost performance Fresnel lens is used as the receiving optical system, which receives the laser-beam reflected by a solid corner cube reflector, and focuses the receiving laser-beam to the InGaAs detector. At the same time, the influences of the concentration to the fluctuation of light intensity were taken into account in the process of measurement, and were eliminated by the method of normalized light intensity. As a result, the measurement error caused by the fluctuation of light intensity was made less than 1%. The experiment of natural gas leakage detection was simulated, and the detection sensitivity is 0.1 x 10(-6) (ratio by volume) with a total path of 320 m. According to the receiving light efficiency of the optical system and the detectable minimum light intensity of the detector, the detectable maximal optical path of the system was counted to be 2 000 m. The results of experiment show that it is a feasible design to use the Fresnel lens as the receiving optical system and can satisfy the demand of the leakage detection of natural gas.

Wireless LAN security management with location detection capability in hospitals.

PubMed

Tanaka, K; Atarashi, H; Yamaguchi, I; Watanabe, H; Yamamoto, R; Ohe, K

2012-01-01

In medical institutions, unauthorized access points and terminals obstruct the stable operation of a large-scale wireless local area network (LAN) system. By establishing a real-time monitoring method to detect such unauthorized wireless devices, we can improve the efficiency of security management. We detected unauthorized wireless devices by using a centralized wireless LAN system and a location detection system at 370 access points at the University of Tokyo Hospital. By storing the detected radio signal strength and location information in a database, we evaluated the risk level from the detection history. We also evaluated the location detection performance in our hospital ward using Wi-Fi tags. The presence of electric waves outside the hospital and those emitted from portable game machines with wireless communication capability was confirmed from the detection result. The location detection performance showed an error margin of approximately 4 m in detection accuracy and approximately 5% in false detection. Therefore, it was effective to consider the radio signal strength as both an index of likelihood at the detection location and an index for the level of risk. We determined the location of wireless devices with high accuracy by filtering the detection results on the basis of radio signal strength and detection history. Results of this study showed that it would be effective to use the developed location database containing radio signal strength and detection history for security management of wireless LAN systems and more general-purpose location detection applications.

The Reliability and Effectiveness of a Radar-Based Animal Detection System

DOT National Transportation Integrated Search

2017-09-22

This document contains data on the reliability and effectiveness of an animal detection system along U.S. Hwy 95 near Bonners Ferry, Idaho. The system uses a Doppler radar to detect large mammals (e.g., deer and elk) when they approach the highway. T...

77 FR 26583 - Notice Pursuant to the National Cooperative Research and Production Act of 1993-Cooperative...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-04

... Production Act of 1993--Cooperative Research Group on Evaluation of Distributed Leak Detection Systems... Institute-- Cooperative Research Group on Evaluation of Distributed Leak Detection Systems--Performance... detection systems for offshore pipelines. Laboratory testing of distributed temperature and distributed...

The Reliability and Effectiveness of a Radar-Based Animal Detection System

DOT National Transportation Integrated Search

2017-09-01

This document contains data on the reliability and effectiveness of an animal detection system along U.S. Hwy 95 near Bonners Ferry, Idaho. The system uses a Doppler radar to detect large mammals (e.g., deer and elk) when they approach the highway. T...

Evaluation of video detection systems, volume 3 : effects of windy conditions in the performance of video detection systems.

DOT National Transportation Integrated Search

2008-05-01

The performance of three Video Detection Systems (VDS), namely Autoscope, Iteris, and Peek, was evaluated : at stop bar and advance locations, at an instrumented signalized intersection located in Rantoul, Illinois, utilizing : a side-by-side install...

Failure Detecting Method of Fault Current Limiter System with Rectifier

NASA Astrophysics Data System (ADS)

Tokuda, Noriaki; Matsubara, Yoshio; Asano, Masakuni; Ohkuma, Takeshi; Sato, Yoshibumi; Takahashi, Yoshihisa

A fault current limiter (FCL) is extensively needed to suppress fault current, particularly required for trunk power systems connecting high-voltage transmission lines, such as 500kV class power system which constitutes the nucleus of the electric power system. We proposed a new type FCL system (rectifier type FCL), consisting of solid-state diodes, DC reactor and bypass AC reactor, and demonstrated the excellent performances of this FCL by developing the small 6.6kV and 66kV model. It is important to detect the failure of power devices used in the rectifier under the normal operating condition, for keeping the excellent reliability of the power system. In this paper, we have proposed a new failure detecting method of power devices most suitable for the rectifier type FCL. This failure detecting system is simple and compact. We have adapted the proposed system to the 66kV prototype single-phase model and successfully demonstrated to detect the failure of power devices.

Board of Regents of the Nevada System of Higher Education, on behalf of the University of Nevada, Reno

DOEpatents

Adams, Jesse D.; Sulchek, Todd A.; Feigin, Stuart C.

2017-07-11

A disclosed chemical detection system for detecting a target material, such as an explosive material, can include a cantilevered probe, a probe heater coupled to the cantilevered probe, and a piezoelectric element disposed on the cantilevered probe. The piezoelectric element can be configured as a detector and/or an actuator. Detection can include, for example, detecting a movement of the cantilevered probe or a property of the cantilevered probe. The movement or a change in the property of the cantilevered probe can occur, for example, by adsorption of the target material, desorption of the target material, reaction of the target material and/or phase change of the target material. Examples of detectable movements and properties include temperature shifts, impedance shifts, and resonant frequency shifts of the cantilevered probe. The overall chemical detection system can be incorporated, for example, into a handheld explosive material detection system.

Research on the system scheme and experiment for the active laser polarization imaging

NASA Astrophysics Data System (ADS)

Fu, Qiang; Duan, Jin; Zhao, Rui; Li, Zheng; Zhang, Su; Zhan, Juntong; Zhu, Yong; Jiang, Hui-Lin

2015-10-01

The polarization imaging detection technology increased the polarization information on the basis of the intensity imaging, which is extensive application in the military and civil and other fields. The research present and development trend of polarization imaging detection technology was introduce, the system scheme of the active polarization imaging detection was put forward, and the key technologies such as the polarization information detection, optical system design, polarization radiation calibration and image fusion approach was analyzed. On this basis, detection system by existing equipment of laboratory was set up, and on the different materials such as wood, metal, plastic and goal was detected by polarization imaging to realize the active polarization imaging detection. The results show that image contrast of the metal and man-made objects is higher, the polarization effect is better, which provided the basis on the better performance of the polarization imaging instruments.

Detection systems for mass spectrometry imaging: a perspective on novel developments with a focus on active pixel detectors.

PubMed

Jungmann, Julia H; Heeren, Ron M A

2013-01-15

Instrumental developments for imaging and individual particle detection for biomolecular mass spectrometry (imaging) and fundamental atomic and molecular physics studies are reviewed. Ion-counting detectors, array detection systems and high mass detectors for mass spectrometry (imaging) are treated. State-of-the-art detection systems for multi-dimensional ion, electron and photon detection are highlighted. Their application and performance in three different imaging modes--integrated, selected and spectral image detection--are described. Electro-optical and microchannel-plate-based systems are contrasted. The analytical capabilities of solid-state pixel detectors--both charge coupled device (CCD) and complementary metal oxide semiconductor (CMOS) chips--are introduced. The Medipix/Timepix detector family is described as an example of a CMOS hybrid active pixel sensor. Alternative imaging methods for particle detection and their potential for future applications are investigated. Copyright © 2012 John Wiley & Sons, Ltd.

Reducing impaired-driving recidivism using advanced vehicle-based alcohol detection systems : a report to Congress

DOT National Transportation Integrated Search

2007-12-01

Vehicle-based alcohol detection systems use technologies designed to detect the presence of alcohol in a driver. Technology suitable for use in all vehicles that will detect an impaired driver faces many challenges including public acceptability, pas...

Determining root correspondence between previously and newly detected objects

DOEpatents

Paglieroni, David W.; Beer, N Reginald

2014-06-17

A system that applies attribute and topology based change detection to networks of objects that were detected on previous scans of a structure, roadway, or area of interest. The attributes capture properties or characteristics of the previously detected objects, such as location, time of detection, size, elongation, orientation, etc. The topology of the network of previously detected objects is maintained in a constellation database that stores attributes of previously detected objects and implicitly captures the geometrical structure of the network. A change detection system detects change by comparing the attributes and topology of new objects detected on the latest scan to the constellation database of previously detected objects.

Performance analysis of a multispectral framing camera for detecting mines in the littoral zone and beach zone

NASA Astrophysics Data System (ADS)

Louchard, Eric; Farm, Brian; Acker, Andrew

2008-04-01

BAE Systems Sensor Systems Identification & Surveillance (IS) has developed, under contract with the Office of Naval Research, a multispectral airborne sensor system and processing algorithms capable of detecting mine-like objects in the surf zone and land mines in the beach zone. BAE Systems has used this system in a blind test at a test range established by the Naval Surface Warfare Center - Panama City Division (NSWC-PCD) at Eglin Air Force Base. The airborne and ground subsystems used in this test are described, with graphical illustrations of the detection algorithms. We report on the performance of the system configured to operate with a human operator analyzing data on a ground station. A subsurface (underwater bottom proud mine in the surf zone and moored mine in shallow water) mine detection capability is demonstrated in the surf zone. Surface float detection and proud land mine detection capability is also demonstrated. Our analysis shows that this BAE Systems-developed multispectral airborne sensor provides a robust technical foundation for a viable system for mine counter-measures, and would be a valuable asset for use prior to an amphibious assault.

A CCTV system with SMS alert (CMDSA): An implementation of pixel processing algorithm for motion detection

NASA Astrophysics Data System (ADS)

Rahman, Nurul Hidayah Ab; Abdullah, Nurul Azma; Hamid, Isredza Rahmi A.; Wen, Chuah Chai; Jelani, Mohamad Shafiqur Rahman Mohd

2017-10-01

Closed-Circuit TV (CCTV) system is one of the technologies in surveillance field to solve the problem of detection and monitoring by providing extra features such as email alert or motion detection. However, detecting and alerting the admin on CCTV system may complicate due to the complexity to integrate the main program with an external Application Programming Interface (API). In this study, pixel processing algorithm is applied due to its efficiency and SMS alert is added as an alternative solution for users who opted out email alert system or have no Internet connection. A CCTV system with SMS alert (CMDSA) was developed using evolutionary prototyping methodology. The system interface was implemented using Microsoft Visual Studio while the backend components, which are database and coding, were implemented on SQLite database and C# programming language, respectively. The main modules of CMDSA are motion detection, capturing and saving video, image processing and Short Message Service (SMS) alert functions. Subsequently, the system is able to reduce the processing time making the detection process become faster, reduce the space and memory used to run the program and alerting the system admin instantly.

Fiber optic thermal/fast neutron and gamma ray scintillation detector

DOEpatents

Neal, John S.; Mihalczo, John T

2007-10-30

A system for detecting fissile and fissionable material originating external to the system includes: a .sup.6Li loaded glass fiber scintillator for detecting thermal neutrons, x-rays and gamma rays; a fast scintillator for detecting fast neutrons, x-rays and gamma rays, the fast scintillator conjoined with the glass fiber scintillator such that the fast scintillator moderates fast neutrons prior to their detection as thermal neutrons by the glass fiber scintillator; and a coincidence detection system for processing the time distributions of arriving signals from the scintillators.

A prototype implementation of a network-level intrusion detection system. Technical report number CS91-11

DOE Office of Scientific and Technical Information (OSTI.GOV)

Heady, R.; Luger, G.F.; Maccabe, A.B.

1991-05-15

This paper presents the implementation of a prototype network level intrusion detection system. The prototype system monitors base level information in network packets (source, destination, packet size, time, and network protocol), learning the normal patterns and announcing anomalies as they occur. The goal of this research is to determine the applicability of current intrusion detection technology to the detection of network level intrusions. In particular, the authors are investigating the possibility of using this technology to detect and react to worm programs.

Systems and methods for detecting a flame in a fuel nozzle of a gas turbine

DOEpatents

Kraemer, Gilbert Otto; Storey, James Michael; Lipinski, John; Mestroni, Julio Enrique; Williamson, David Lee; Marshall, Jason Randolph; Krull, Anthony

2013-05-07

A system may detect a flame about a fuel nozzle of a gas turbine. The gas turbine may have a compressor and a combustor. The system may include a first pressure sensor, a second pressure sensor, and a transducer. The first pressure sensor may detect a first pressure upstream of the fuel nozzle. The second pressure sensor may detect a second pressure downstream of the fuel nozzle. The transducer may be operable to detect a pressure difference between the first pressure sensor and the second pressure sensor.

RADIATION DETECTOR SYSTEM

DOEpatents

Gundlach, J.C.; Kelley, G.G.

1958-02-25

This patent relates to radiation detection devices and presents a unique detection system especialiy desirable for portable type instruments using a Geiger-Mueller for a high voltage battery, thereby reducing the size and weight of the instrument, by arranging a one-shot multivibrator to recharge a capacitance applying operating potential to tho Geiger-Mueller tube each time a nuclear particle is detected. When detection occurs, the multivibrator further delivers a pulse to an appropriate indicator doing away with the necessity for the pulse amplifier conventionally intermediate between the detector and indicator in pulse detection systems.

CPAD: Cyber-Physical Attack Detection

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ferragut, Erik M; Laska, Jason A

The CPAD technology relates to anomaly detection and more specifically to cyber physical attack detection. It infers underlying physical relationships between components by analyzing the sensor measurements of a system. It then uses these measurements to detect signs of a non-physically realizable state, which is indicative of an integrity attack on the system. CPAD can be used on any highly-instrumented cyber-physical system to detect integrity attacks and identify the component or components compromised. It has applications to power transmission and distribution, nuclear and industrial plants, and complex vehicles.

A Novel Technique to Detect Code for SAC-OCDMA System

NASA Astrophysics Data System (ADS)

Bharti, Manisha; Kumar, Manoj; Sharma, Ajay K.

2018-04-01

The main task of optical code division multiple access (OCDMA) system is the detection of code used by a user in presence of multiple access interference (MAI). In this paper, new method of detection known as XOR subtraction detection for spectral amplitude coding OCDMA (SAC-OCDMA) based on double weight codes has been proposed and presented. As MAI is the main source of performance deterioration in OCDMA system, therefore, SAC technique is used in this paper to eliminate the effect of MAI up to a large extent. A comparative analysis is then made between the proposed scheme and other conventional detection schemes used like complimentary subtraction detection, AND subtraction detection and NAND subtraction detection. The system performance is characterized by Q-factor, BER and received optical power (ROP) with respect to input laser power and fiber length. The theoretical and simulation investigations reveal that the proposed detection technique provides better quality factor, security and received power in comparison to other conventional techniques. The wide opening of eye in case of proposed technique also proves its robustness.

46 CFR 154.1350 - Flammable gas detection system.

Code of Federal Regulations, 2014 CFR

2014-10-01

... each flammable gas detection system that is in a gas-dangerous space or area must meet §§ 154.1000... 46 Shipping 5 2014-10-01 2014-10-01 false Flammable gas detection system. 154.1350 Section 154.1350 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS CARGOES...

46 CFR 154.1350 - Flammable gas detection system.

Code of Federal Regulations, 2012 CFR

2012-10-01

... each flammable gas detection system that is in a gas-dangerous space or area must meet §§ 154.1000... 46 Shipping 5 2012-10-01 2012-10-01 false Flammable gas detection system. 154.1350 Section 154.1350 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS CARGOES...

40 CFR 63.11457 - What are the recordkeeping requirements?

Code of Federal Regulations, 2010 CFR

2010-07-01

... calibration and maintenance records. (7) For each bag leak detection system, the records specified in paragraphs (a)(7)(i) through (iii) of this section. (i) Records of the bag leak detection system output; (ii) Records of bag leak detection system adjustments, including the date and time of the adjustment, the...

40 CFR 63.11552 - What are my monitoring requirements?

Code of Federal Regulations, 2010 CFR

2010-07-01

..., operate, and maintain a bag leak detection system for each fabric filter according to the requirements in..., operate, and maintain a bag leak detection system for each fabric filter according to paragraphs (c)(1) through (4) of this section. (1) Each bag leak detection system must meet the specifications and...

40 CFR 63.11583 - What are my monitoring requirements?

Code of Federal Regulations, 2010 CFR

2010-07-01

... preparation operation are in target HAP service: (a) Operate a bag leak detection system with alarm that will alert operators of a leak in the control device filter material. If a bag leak detection system with... install, calibrate, operate, and maintain each bag leak detection system and alarm according to...

40 CFR 270.17 - Specific part B information requirements for surface impoundments.

Code of Federal Regulations, 2010 CFR

2010-07-01

... double liner and leak (leachate) detection, collection, and removal system, if the surface impoundment... double liners and a leak detection, collection, and removal system or alternative design is sought as... detection system is located in a saturated zone, submit detailed plans and an engineering report explaining...

Automatic patient respiration failure detection system with wireless transmission

NASA Technical Reports Server (NTRS)

Dimeff, J.; Pope, J. M.

1968-01-01

Automatic respiration failure detection system detects respiration failure in patients with a surgically implanted tracheostomy tube, and actuates an audible and/or visual alarm. The system incorporates a miniature radio transmitter so that the patient is unencumbered by wires yet can be monitored from a remote location.

Evaluation of video detection systems, volume 4 : effects of adverse weather conditions in the performance of video detection systems.

DOT National Transportation Integrated Search

2009-03-01

The performance of three video detection systems (VDS): Iteris, Autoscope, and Peek, was evaluated : using a side-by-side installation at a signalized intersection under various adverse weather conditions including : rain and snow in both day and nig...

Evaluation of video detection systems, volume 1 : effects of configuration changes in the performance of video detection systems.

DOT National Transportation Integrated Search

2009-10-01

The effects of modifying the configuration of three video detection (VD) systems (Iteris, Autoscope, and Peek) : are evaluated in daytime and nighttime conditions. Four types of errors were used: false, missed, stuck-on, and : dropped calls. The thre...

Research on the attitude detection technology of the tetrahedron robot

NASA Astrophysics Data System (ADS)

Gong, Hao; Chen, Keshan; Ren, Wenqiang; Cai, Xin

2017-10-01

The traditional attitude detection technology can't tackle the problem of attitude detection of the polyhedral robot. Thus we propose a novel algorithm of multi-sensor data fusion which is based on Kalman filter. In the algorithm a tetrahedron robot is investigated. We devise an attitude detection system for the polyhedral robot and conduct the verification of data fusion algorithm. It turns out that the minimal attitude detection system we devise could capture attitudes of the tetrahedral robot in different working conditions. Thus the Kinematics model we establish for the tetrahedron robot is correct and the feasibility of the attitude detection system is proven.

Systems and methods of detecting force and stress using tetrapod nanocrystal

DOEpatents

Choi, Charina L.; Koski, Kristie J.; Sivasankar, Sanjeevi; Alivisatos, A. Paul

2013-08-20

Systems and methods of detecting force on the nanoscale including methods for detecting force using a tetrapod nanocrystal by exposing the tetrapod nanocrystal to light, which produces a luminescent response by the tetrapod nanocrystal. The method continues with detecting a difference in the luminescent response by the tetrapod nanocrystal relative to a base luminescent response that indicates a force between a first and second medium or stresses or strains experienced within a material. Such systems and methods find use with biological systems to measure forces in biological events or interactions.

Inertial navigation sensor integrated obstacle detection system

NASA Technical Reports Server (NTRS)

Bhanu, Bir (Inventor); Roberts, Barry A. (Inventor)

1992-01-01

A system that incorporates inertial sensor information into optical flow computations to detect obstacles and to provide alternative navigational paths free from obstacles. The system is a maximally passive obstacle detection system that makes selective use of an active sensor. The active detection typically utilizes a laser. Passive sensor suite includes binocular stereo, motion stereo and variable fields-of-view. Optical flow computations involve extraction, derotation and matching of interest points from sequential frames of imagery, for range interpolation of the sensed scene, which in turn provides obstacle information for purposes of safe navigation.

Eddy Current System for Detection of Cracking Beneath Braiding in Corrugated Metal Hose

NASA Astrophysics Data System (ADS)

Wincheski, Buzz; Simpson, John; Hall, George

2009-03-01

In this paper an eddy current system for the detection of partially-through-the-thickness cracks in corrugated metal hose is presented. Design criteria based upon the geometry and conductivity of the part are developed and applied to the fabrication of a prototype inspection system. Experimental data are used to highlight the capabilities of the system and an image processing technique is presented to improve flaw detection capabilities. A case study for detection of cracking damage in a space shuttle radiator retract flex hoses is also presented.

Eddy Current System for Detection of Cracking Beneath Braiding in Corrugated Metal Hose

NASA Technical Reports Server (NTRS)

Wincheski, Buzz; Simpson, John; Hall, George

2008-01-01

In this paper an eddy current system for the detection of partially-through-the-thickness cracks in corrugated metal hose is presented. Design criteria based upon the geometry and conductivity of the part are developed and applied to the fabrication of a prototype inspection system. Experimental data are used to highlight the capabilities of the system and an image processing technique is presented to improve flaw detection capabilities. A case study for detection of cracking damage in a space shuttle radiator retract flex hoses is also presented.

Photon Counting System for High-Sensitivity Detection of Bioluminescence at Optical Fiber End.

PubMed

Iinuma, Masataka; Kadoya, Yutaka; Kuroda, Akio

2016-01-01

The technique of photon counting is widely used for various fields and also applicable to a high-sensitivity detection of luminescence. Thanks to recent development of single photon detectors with avalanche photodiodes (APDs), the photon counting system with an optical fiber has become powerful for a detection of bioluminescence at an optical fiber end, because it allows us to fully use the merits of compactness, simple operation, highly quantum efficiency of the APD detectors. This optical fiber-based system also has a possibility of improving the sensitivity to a local detection of Adenosine triphosphate (ATP) by high-sensitivity detection of the bioluminescence. In this chapter, we are introducing a basic concept of the optical fiber-based system and explaining how to construct and use this system.

An ultrasound transient elastography system with coded excitation.

PubMed

Diao, Xianfen; Zhu, Jing; He, Xiaonian; Chen, Xin; Zhang, Xinyu; Chen, Siping; Liu, Weixiang

2017-06-28

Ultrasound transient elastography technology has found its place in elastography because it is safe and easy to operate. However, it's application in deep tissue is limited. The aim of this study is to design an ultrasound transient elastography system with coded excitation to obtain greater detection depth. The ultrasound transient elastography system requires tissue vibration to be strictly synchronous with ultrasound detection. Therefore, an ultrasound transient elastography system with coded excitation was designed. A central component of this transient elastography system was an arbitrary waveform generator with multi-channel signals output function. This arbitrary waveform generator was used to produce the tissue vibration signal, the ultrasound detection signal and the synchronous triggering signal of the radio frequency data acquisition system. The arbitrary waveform generator can produce different forms of vibration waveform to induce different shear wave propagation in the tissue. Moreover, it can achieve either traditional pulse-echo detection or a phase-modulated or a frequency-modulated coded excitation. A 7-chip Barker code and traditional pulse-echo detection were programmed on the designed ultrasound transient elastography system to detect the shear wave in the phantom excited by the mechanical vibrator. Then an elasticity QA phantom and sixteen in vitro rat livers were used for performance evaluation of the two detection pulses. The elasticity QA phantom's results show that our system is effective, and the rat liver results show the detection depth can be increased more than 1 cm. In addition, the SNR (signal-to-noise ratio) is increased by 15 dB using the 7-chip Barker coded excitation. Applying 7-chip Barker coded excitation technique to the ultrasound transient elastography can increase the detection depth and SNR. Using coded excitation technology to assess the human liver, especially in obese patients, may be a good choice.

Attribute and topology based change detection in a constellation of previously detected objects

DOEpatents

Paglieroni, David W.; Beer, Reginald N.

2016-01-19

A system that applies attribute and topology based change detection to networks of objects that were detected on previous scans of a structure, roadway, or area of interest. The attributes capture properties or characteristics of the previously detected objects, such as location, time of detection, size, elongation, orientation, etc. The topology of the network of previously detected objects is maintained in a constellation database that stores attributes of previously detected objects and implicitly captures the geometrical structure of the network. A change detection system detects change by comparing the attributes and topology of new objects detected on the latest scan to the constellation database of previously detected objects.

Design of a Multi-Sensor Cooperation Travel Environment Perception System for Autonomous Vehicle

PubMed Central

Chen, Long; Li, Qingquan; Li, Ming; Zhang, Liang; Mao, Qingzhou

2012-01-01

This paper describes the environment perception system designed for intelligent vehicle SmartV-II, which won the 2010 Future Challenge. This system utilizes the cooperation of multiple lasers and cameras to realize several necessary functions of autonomous navigation: road curb detection, lane detection and traffic sign recognition. Multiple single scan lasers are integrated to detect the road curb based on Z-variance method. Vision based lane detection is realized by two scans method combining with image model. Haar-like feature based method is applied for traffic sign detection and SURF matching method is used for sign classification. The results of experiments validate the effectiveness of the proposed algorithms and the whole system.

Characterization of System Status Signals for Multivariate Time Series Discretization Based on Frequency and Amplitude Variation

PubMed Central

2018-01-01

Many fault detection methods have been proposed for monitoring the health of various industrial systems. Characterizing the monitored signals is a prerequisite for selecting an appropriate detection method. However, fault detection methods tend to be decided with user’s subjective knowledge or their familiarity with the method, rather than following a predefined selection rule. This study investigates the performance sensitivity of two detection methods, with respect to status signal characteristics of given systems: abrupt variance, characteristic indicator, discernable frequency, and discernable index. Relation between key characteristics indicators from four different real-world systems and the performance of two fault detection methods using pattern recognition are evaluated. PMID:29316731

Arduino-based noise robust online heart-rate detection.

PubMed

Das, Sangita; Pal, Saurabh; Mitra, Madhuchhanda

2017-04-01

This paper introduces a noise robust real time heart rate detection system from electrocardiogram (ECG) data. An online data acquisition system is developed to collect ECG signals from human subjects. Heart rate is detected using window-based autocorrelation peak localisation technique. A low-cost Arduino UNO board is used to implement the complete automated process. The performance of the system is compared with PC-based heart rate detection technique. Accuracy of the system is validated through simulated noisy ECG data with various levels of signal to noise ratio (SNR). The mean percentage error of detected heart rate is found to be 0.72% for the noisy database with five different noise levels.

Prospects for detecting decreasing exoplanet frequency with main-sequence age using PLATO

NASA Astrophysics Data System (ADS)

Veras, Dimitri; Brown, David J. A.; Mustill, Alexander J.; Pollacco, Don

2015-10-01

The space mission PLATO will usher in a new era of exoplanetary science by expanding our current inventory of transiting systems and constraining host star ages, which are currently highly uncertain. This capability might allow PLATO to detect changes in planetary system architecture with time, particularly because planetary scattering due to Lagrange instability may be triggered long after the system was formed. Here, we utilize previously published instability time-scale prescriptions to determine PLATO's capability to detect a trend of decreasing planet frequency with age for systems with equal-mass planets. For two-planet systems, our results demonstrate that PLATO may detect a trend for planet masses which are at least as massive as super-Earths. For systems with three or more planets, we link their initial compactness to potentially detectable frequency trends in order to aid future investigations when these populations will be better characterized.

Prospects for detecting decreasing exoplanet frequency with main-sequence age using PLATO

NASA Astrophysics Data System (ADS)

Veras, D.; Brown, D. J. A.; Mustill, A. J.; Pollacco, D.

2017-09-01

The space mission PLATO will usher in a new era of exoplanetary science by expanding our current inventory of transiting systems and constraining host star ages, which are currently highly uncertain. This capability might allow PLATO to detect changes in planetary system architecture with time, particularly because planetary scattering due to Lagrange instability may be triggered long after the system was formed. Here, we utilize previously published instability time-scale prescriptions to determine PLATO's capability to detect a trend of decreasing planet frequency with age for systems with equal- mass planets. For two-planet systems, our results demonstrate that PLATO may detect a trend for planet masses which are at least as massive as super-Earths. For systems with three or more planets, we link their initial compactness to potentially detectable frequency trends in order to aid future investigations when these populations will be better characterized.

Systems for detecting charged particles in object inspection

DOEpatents

Morris, Christopher L.; Makela, Mark F.

2013-08-20

Techniques, apparatus and systems for detecting particles such as muons. In one implementation, a monitoring system has a cosmic ray-produced charged particle tracker with a plurality of drift cells. The drift cells, which can be for example aluminum drift tubes, can be arranged at least above and below a volume to be scanned to thereby track incoming and outgoing charged particles, such as cosmic ray-produced muons, while also detecting gamma rays. The system can selectively detect devices or materials, such as iron, lead, gold and/or tungsten, occupying the volume from multiple scattering of the charged particles passing through the volume and can also detect any radioactive sources occupying the volume from gamma rays emitted therefrom. If necessary, the drift tubes can be sealed to eliminate the need for a gas handling system. The system can be employed to inspect occupied vehicles at border crossings for nuclear threat objects.

Development of yarn breakage detection software system based on machine vision

NASA Astrophysics Data System (ADS)

Wang, Wenyuan; Zhou, Ping; Lin, Xiangyu

2017-10-01

For questions spinning mills and yarn breakage cannot be detected in a timely manner, and save the cost of textile enterprises. This paper presents a software system based on computer vision for real-time detection of yarn breakage. The system and Windows8.1 system Tablet PC, cloud server to complete the yarn breakage detection and management. Running on the Tablet PC software system is designed to collect yarn and location information for analysis and processing. And will be processed after the information through the Wi-Fi and http protocol sent to the cloud server to store in the Microsoft SQL2008 database. In order to follow up on the yarn break information query and management. Finally sent to the local display on time display, and remind the operator to deal with broken yarn. The experimental results show that the system of missed test rate not more than 5%o, and no error detection.

Flight elements: Fault detection and fault management

NASA Technical Reports Server (NTRS)

Lum, H.; Patterson-Hine, A.; Edge, J. T.; Lawler, D.

1990-01-01

Fault management for an intelligent computational system must be developed using a top down integrated engineering approach. An approach proposed includes integrating the overall environment involving sensors and their associated data; design knowledge capture; operations; fault detection, identification, and reconfiguration; testability; causal models including digraph matrix analysis; and overall performance impacts on the hardware and software architecture. Implementation of the concept to achieve a real time intelligent fault detection and management system will be accomplished via the implementation of several objectives, which are: Development of fault tolerant/FDIR requirement and specification from a systems level which will carry through from conceptual design through implementation and mission operations; Implementation of monitoring, diagnosis, and reconfiguration at all system levels providing fault isolation and system integration; Optimize system operations to manage degraded system performance through system integration; and Lower development and operations costs through the implementation of an intelligent real time fault detection and fault management system and an information management system.

Driver fatigue detection based on eye state.

PubMed

Lin, Lizong; Huang, Chao; Ni, Xiaopeng; Wang, Jiawen; Zhang, Hao; Li, Xiao; Qian, Zhiqin

2015-01-01

Nowadays, more and more traffic accidents occur because of driver fatigue. In order to reduce and prevent it, in this study, a calculation method using PERCLOS (percentage of eye closure time) parameter characteristics based on machine vision was developed. It determined whether a driver's eyes were in a fatigue state according to the PERCLOS value. The overall workflow solutions included face detection and tracking, detection and location of the human eye, human eye tracking, eye state recognition, and driver fatigue testing. The key aspects of the detection system incorporated the detection and location of human eyes and driver fatigue testing. The simplified method of measuring the PERCLOS value of the driver was to calculate the ratio of the eyes being open and closed with the total number of frames for a given period. If the eyes were closed more than the set threshold in the total number of frames, the system would alert the driver. Through many experiments, it was shown that besides the simple detection algorithm, the rapid computing speed, and the high detection and recognition accuracies of the system, the system was demonstrated to be in accord with the real-time requirements of a driver fatigue detection system.

Concept of electro-optical sensor module for sniper detection system

NASA Astrophysics Data System (ADS)

Trzaskawka, Piotr; Dulski, Rafal; Kastek, Mariusz

2010-10-01

The paper presents an initial concept of the electro-optical sensor unit for sniper detection purposes. This unit, comprising of thermal and daylight cameras, can operate as a standalone device but its primary application is a multi-sensor sniper and shot detection system. Being a part of a larger system it should contribute to greater overall system efficiency and lower false alarm rate thanks to data and sensor fusion techniques. Additionally, it is expected to provide some pre-shot detection capabilities. Generally acoustic (or radar) systems used for shot detection offer only "after-the-shot" information and they cannot prevent enemy attack, which in case of a skilled sniper opponent usually means trouble. The passive imaging sensors presented in this paper, together with active systems detecting pointed optics, are capable of detecting specific shooter signatures or at least the presence of suspected objects in the vicinity. The proposed sensor unit use thermal camera as a primary sniper and shot detection tool. The basic camera parameters such as focal plane array size and type, focal length and aperture were chosen on the basis of assumed tactical characteristics of the system (mainly detection range) and current technology level. In order to provide costeffective solution the commercially available daylight camera modules and infrared focal plane arrays were tested, including fast cooled infrared array modules capable of 1000 fps image acquisition rate. The daylight camera operates as a support, providing corresponding visual image, easier to comprehend for a human operator. The initial assumptions concerning sensor operation were verified during laboratory and field test and some example shot recording sequences are presented.

"Smoke": Characterization Of Smoke Particulate For Spacecraft Fire Detection

NASA Technical Reports Server (NTRS)

Urban, David L.; Mulholland, George W.; Yang, Jiann; Cleary, Thomas G.; Yuan, Zeng-Guang

2003-01-01

The "Smoke" experiment is a flight definition investigation that seeks to increase our understanding of spacecraft fire detection through measurements of particulate size distributions of preignition smokes from typical spacecraft materials. Owing to the catastrophic risk posed by even a very small fire in a spacecraft, the design goal for spacecraft fire detection is to detect the fire as quickly as possible, preferably in the preignition phase before a real flaming fire has developed. Consequently the target smoke for detection is typically not soot (typical of established hydrocarbon fires) but instead, pyrolysis products, and recondensed polymer particles. At the same time, false alarms are extremely costly as the crew and the ground team must respond quickly to every alarm. The U.S. Space Shuttle (STS: Space Transportation System) and the International Space Station (ISS) both use smoke detection as the primary means of fire detection. These two systems were designed in the absence of any data concerning low-gravity smoke particle (and background dust) size distributions. The STS system uses an ionization detector coupled with a sampling pump and the ISS system is a forward light scattering detector operating in the near IR. These two systems have significantly different sensitivities with the ionization detector being most sensitive (on a mass concentration basis) to smaller particulate and the light scattering detector being most sensitive to particulate that is larger than 1 micron. Since any smoke detection system has inherent size sensitivity characteristics, proper design of future smoke detection systems will require an understanding of the background and alarm particle size distributions that can be expected in a space environment.

Exploiting semantics for sensor re-calibration in event detection systems

NASA Astrophysics Data System (ADS)

Vaisenberg, Ronen; Ji, Shengyue; Hore, Bijit; Mehrotra, Sharad; Venkatasubramanian, Nalini

2008-01-01

Event detection from a video stream is becoming an important and challenging task in surveillance and sentient systems. While computer vision has been extensively studied to solve different kinds of detection problems over time, it is still a hard problem and even in a controlled environment only simple events can be detected with a high degree of accuracy. Instead of struggling to improve event detection using image processing only, we bring in semantics to direct traditional image processing. Semantics are the underlying facts that hide beneath video frames, which can not be "seen" directly by image processing. In this work we demonstrate that time sequence semantics can be exploited to guide unsupervised re-calibration of the event detection system. We present an instantiation of our ideas by using an appliance as an example--Coffee Pot level detection based on video data--to show that semantics can guide the re-calibration of the detection model. This work exploits time sequence semantics to detect when re-calibration is required to automatically relearn a new detection model for the newly evolved system state and to resume monitoring with a higher rate of accuracy.

Electro-optical system for gunshot detection: analysis, concept, and performance

NASA Astrophysics Data System (ADS)

Kastek, M.; Dulski, R.; Madura, H.; Trzaskawka, P.; Bieszczad, G.; Sosnowski, T.

2011-08-01

The paper discusses technical possibilities to build an effective electro-optical sensor unit for sniper detection using infrared cameras. This unit, comprising of thermal and daylight cameras, can operate as a standalone device but its primary application is a multi-sensor sniper and shot detection system. At first, the analysis was presented of three distinguished phases of sniper activity: before, during and after the shot. On the basis of experimental data the parameters defining the relevant sniper signatures were determined which are essential in assessing the capability of infrared camera to detect sniper activity. A sniper body and muzzle flash were analyzed as targets and the descriptions of phenomena which make it possible to detect sniper activities in infrared spectra as well as analysis of physical limitations were performed. The analyzed infrared systems were simulated using NVTherm software. The calculations for several cameras, equipped with different lenses and detector types were performed. The simulation of detection ranges was performed for the selected scenarios of sniper detection tasks. After the analysis of simulation results, the technical specifications of infrared sniper detection system were discussed, required to provide assumed detection range. Finally the infrared camera setup was proposed which can detected sniper from 1000 meters range.

Integrated analysis of error detection and recovery

NASA Technical Reports Server (NTRS)

Shin, K. G.; Lee, Y. H.

1985-01-01

An integrated modeling and analysis of error detection and recovery is presented. When fault latency and/or error latency exist, the system may suffer from multiple faults or error propagations which seriously deteriorate the fault-tolerant capability. Several detection models that enable analysis of the effect of detection mechanisms on the subsequent error handling operations and the overall system reliability were developed. Following detection of the faulty unit and reconfiguration of the system, the contaminated processes or tasks have to be recovered. The strategies of error recovery employed depend on the detection mechanisms and the available redundancy. Several recovery methods including the rollback recovery are considered. The recovery overhead is evaluated as an index of the capabilities of the detection and reconfiguration mechanisms.

Information Warfare-Worthy Jamming Attack Detection Mechanism for Wireless Sensor Networks Using a Fuzzy Inference System

PubMed Central

Misra, Sudip; Singh, Ranjit; Rohith Mohan, S. V.

2010-01-01

The proposed mechanism for jamming attack detection for wireless sensor networks is novel in three respects: firstly, it upgrades the jammer to include versatile military jammers; secondly, it graduates from the existing node-centric detection system to the network-centric system making it robust and economical at the nodes, and thirdly, it tackles the problem through fuzzy inference system, as the decision regarding intensity of jamming is seldom crisp. The system with its high robustness, ability to grade nodes with jamming indices, and its true-detection rate as high as 99.8%, is worthy of consideration for information warfare defense purposes. PMID:22319307

On Modeling of Adversary Behavior and Defense for Survivability of Military MANET Applications

DTIC Science & Technology

2015-01-01

anomaly detection technique. b) A system-level majority-voting based intrusion detection system with m being the number of verifiers used to perform...pp. 1254 - 1263. [5] R. Mitchell, and I.R. Chen, “Adaptive Intrusion Detection for Unmanned Aircraft Systems based on Behavior Rule Specification...and adaptively trigger the best attack strategies while avoiding detection and eviction. The second step is to model defense behavior of defenders

The Monitoring, Detection, Isolation and Assessment of Information Warfare Attacks Through Multi-Level, Multi-Scale System Modeling and Model Based Technology

DTIC Science & Technology

2004-01-01

login identity to the one under which the system call is executed, the parameters of the system call execution - file names including full path...Anomaly detection COAST-EIMDT Distributed on target hosts EMERALD Distributed on target hosts and security servers Signature recognition Anomaly...uses a centralized architecture, and employs an anomaly detection technique for intrusion detection. The EMERALD project [80] proposes a

Radiological Health Protection Issues Associated with Use of Active Detection Technology Systems for Detection of Radioactive Threat Materials

DTIC Science & Technology

2013-07-01

detection system available will simply register events resulting from natural background radiation if a suitable source emission is not employed. The...random fluctuations in the natural background radiation level. Noise within the detection system can result from any of the various components that...Uritani et al., 1994). Nothing can generally be done to reduce or stabilize the amount of natural background radiation present for nonstationary

Improved Detection System Description and New Method for Accurate Calibration of Micro-Channel Plate Based Instruments and Its Use in the Fast Plasma Investigation on NASA's Magnetospheric MultiScale Mission

NASA Technical Reports Server (NTRS)

Gliese, U.; Avanov, L. A.; Barrie, A. C.; Kujawski, J. T.; Mariano, A. J.; Tucker, C. J.; Chornay, D. J.; Cao, N. T.; Gershman, D. J.; Dorelli, J. C.;

Intrusion detection: systems and models

NASA Technical Reports Server (NTRS)

Sherif, J. S.; Dearmond, T. G.

2002-01-01

This paper puts forward a review of state of the art and state of the applicability of intrusion detection systems, and models. The paper also presents a classfication of literature pertaining to intrusion detection.

Cold-Rolled Strip Steel Stress Detection Technology Based on a Magnetoresistance Sensor and the Magnetoelastic Effect

PubMed Central

Guan, Ben; Zang, Yong; Han, Xiaohui; Zheng, Kailun

2018-01-01

Driven by the demands for contactless stress detection, technologies are being used for shape control when producing cold-rolled strips. This paper presents a novel contactless stress detection technology based on a magnetoresistance sensor and the magnetoelastic effect, enabling the detection of internal stress in manufactured cold-rolled strips. An experimental device was designed and produced. Characteristics of this detection technology were investigated through experiments assisted by theoretical analysis. Theoretically, a linear correlation exists between the internal stress of strip steel and the voltage output of a magneto-resistive sensor. Therefore, for this stress detection system, the sensitivity of the stress detection was adjusted by adjusting the supply voltage of the magnetoresistance sensor, detection distance, and other relevant parameters. The stress detection experimental results showed that this detection system has good repeatability and linearity. The detection error was controlled within 1.5%. Moreover, the intrinsic factors of the detected strip steel, including thickness, carbon percentage, and crystal orientation, also affected the sensitivity of the detection system. The detection technology proposed in this research enables online contactless detection and meets the requirements for cold-rolled steel strips. PMID:29883387

Cold-Rolled Strip Steel Stress Detection Technology Based on a Magnetoresistance Sensor and the Magnetoelastic Effect.

PubMed

Guan, Ben; Zang, Yong; Han, Xiaohui; Zheng, Kailun

2018-05-21

Driven by the demands for contactless stress detection, technologies are being used for shape control when producing cold-rolled strips. This paper presents a novel contactless stress detection technology based on a magnetoresistance sensor and the magnetoelastic effect, enabling the detection of internal stress in manufactured cold-rolled strips. An experimental device was designed and produced. Characteristics of this detection technology were investigated through experiments assisted by theoretical analysis. Theoretically, a linear correlation exists between the internal stress of strip steel and the voltage output of a magneto-resistive sensor. Therefore, for this stress detection system, the sensitivity of the stress detection was adjusted by adjusting the supply voltage of the magnetoresistance sensor, detection distance, and other relevant parameters. The stress detection experimental results showed that this detection system has good repeatability and linearity. The detection error was controlled within 1.5%. Moreover, the intrinsic factors of the detected strip steel, including thickness, carbon percentage, and crystal orientation, also affected the sensitivity of the detection system. The detection technology proposed in this research enables online contactless detection and meets the requirements for cold-rolled steel strips.

Field programmable gate array based fuzzy neural signal processing system for differential diagnosis of QRS complex tachycardia and tachyarrhythmia in noisy ECG signals.

PubMed

Chowdhury, Shubhajit Roy

2012-04-01

The paper reports of a Field Programmable Gate Array (FPGA) based embedded system for detection of QRS complex in a noisy electrocardiogram (ECG) signal and thereafter differential diagnosis of tachycardia and tachyarrhythmia. The QRS complex has been detected after application of entropy measure of fuzziness to build a detection function of ECG signal, which has been previously filtered to remove power line interference and base line wander. Using the detected QRS complexes, differential diagnosis of tachycardia and tachyarrhythmia has been performed. The entire algorithm has been realized in hardware on an FPGA. Using the standard CSE ECG database, the algorithm performed highly effectively. The performance of the algorithm in respect of QRS detection with sensitivity (Se) of 99.74% and accuracy of 99.5% is achieved when tested using single channel ECG with entropy criteria. The performance of the QRS detection system has been compared and found to be better than most of the QRS detection systems available in literature. Using the system, 200 patients have been diagnosed with an accuracy of 98.5%.

On-road vehicle detection: a review.

PubMed

Sun, Zehang; Bebis, George; Miller, Ronald

2006-05-01

Developing on-board automotive driver assistance systems aiming to alert drivers about driving environments, and possible collision with other vehicles has attracted a lot of attention lately. In these systems, robust and reliable vehicle detection is a critical step. This paper presents a review of recent vision-based on-road vehicle detection systems. Our focus is on systems where the camera is mounted on the vehicle rather than being fixed such as in traffic/driveway monitoring systems. First, we discuss the problem of on-road vehicle detection using optical sensors followed by a brief review of intelligent vehicle research worldwide. Then, we discuss active and passive sensors to set the stage for vision-based vehicle detection. Methods aiming to quickly hypothesize the location of vehicles in an image as well as to verify the hypothesized locations are reviewed next. Integrating detection with tracking is also reviewed to illustrate the benefits of exploiting temporal continuity for vehicle detection. Finally, we present a critical overview of the methods discussed, we assess their potential for future deployment, and we present directions for future research.

Terahertz imaging system for stand-off detection of threats

NASA Astrophysics Data System (ADS)

Hübers, H.-W.; Semenov, A. D.; Richter, H.; Böttger, U.

2007-04-01

Suicide bombers and hidden bombs or explosives have become serious threats especially for mass transportation. Until now there exists no established system which can be used against these threats. Therefore new technologies especially for stand-off detection of threats are required. Terahertz (THz) rays offer an alternative inspection method, which can cope with these new challenges. Major advantages of THz radiation as compared to other spectral regions are the possibility to penetrate through clothes and that THz radiation is not harmful for human health. In this report the design and results of a THz stand-off detection system will be presented. The sensor is based on active illumination of the object and sensitive heterodyne detection of reflected and backscattered radiation. The system operates at about 0.8 THz. A THz laser is used for illumination and a superconducting hot-electron bolometric mixer for detection. The local oscillator required for heterodyne detection is a multiplied microwave source. The optical system is designed to allow for stand-off detection at 20 m with a spatial resolution less than 2 cm.

A differential detection scheme of spectral shifts in long-period fiber gratings

NASA Astrophysics Data System (ADS)

Zhelyazkova, Katerina; Eftimov, Tinko; Smietana, Mateusz; Bock, Wojtek

2010-10-01

In this work we present an analysis of the response of a compact, simple and inexpensive optoelectronic sensor system intended to detect spectral shifts of a long-period fiber grating (LPG). The system makes use of a diffraction grating and a couple of receiving optical fibers that pick up signals at two different wavelengths. This differential detection system provides the same useful information from an LPG-based sensor as with a conventional laboratory system using optical spectrum analyzers for monitoring the minimum offset of LPG. The design of the fiber detection pair as a function of the parameters of the dispersion grating, the pick-up fiber and the LPG parameters, is presented in detail. Simulation of the detection system responses is presented using real from spectral shifts in nano-coated LPGs caused by the evaporation of various liquids such as water, ethanol and acetone, which are examples of corrosive, flammable and hazardous substances. Fiber optic sensors with similar detection can find applications in structural health monitoring for moisture detection, monitoring the spillage of toxic and flammable substances in industry etc.

46 CFR 154.1810 - Cargo manual.

Code of Federal Regulations, 2010 CFR

2010-10-01

... leakage. (4) The use of the firefighting systems on the vessel. (5) The features of the cargo containment... detection systems. (x) Alarm or safety indication systems. (xi) Cargo jettisoning system. (xii) The system...) A description of gas detection systems and alarm or safety systems. (15) A description of the...

Detection of Helicobacter pylori DNA in inflamed dental pulp specimens from Japanese children and adolescents.

PubMed

Ogaya, Yuko; Nomura, Ryota; Watanabe, Yoshiyuki; Nakano, Kazuhiko

2015-01-01

The oral cavity has been implicated as a source of Helicobacter pylori infection in childhood. Various PCR methods have been used to detect H. pylori DNA in oral specimens with various detection rates reported. Such disparity in detection rates complicates the estimation of the true infection rate of H. pylori in the oral cavity. In the present study, we constructed a novel PCR system for H. pylori detection and used it to analyse oral specimens. Firstly, the nucleotide alignments of genes commonly used for H. pylori detection were compared using the complete genome information for 48 strains registered in the GenBank database. Candidate primer sets with an estimated amplification size of approximately 300-400 bp were selected, and the specificity and sensitivity of the detection system using each primer set were evaluated. Five sets of primers targeting ureA were considered appropriate, of which a single primer set was chosen for inclusion in the PCR system. The sensitivity of the system was considered appropriate and its detection limit established as one to ten cells per reaction. The novel PCR system was used to examine H. pylori distribution in oral specimens (40 inflamed pulp tissues, 40 saliva samples) collected from Japanese children, adolescents and young adults. PCR analysis revealed that the detection rate of H. pylori in inflamed pulp was 15 %, whereas no positive reaction was found in any of the saliva specimens. Taken together, our novel PCR system was found to be reliable for detecting H. pylori. The results obtained showed that H. pylori was detected in inflamed pulp but not saliva specimens, indicating that an infected root canal may be a reservoir for H. pylori. © 2015 The Authors.

40 CFR 264.1101 - Design and operating standards.

Code of Federal Regulations, 2010 CFR

2010-07-01

... hazardous waste (e.g., upon detection of leakage from the primary barrier) the owner or operator must: (A... constituents into the barrier, and a leak detection system that is capable of detecting failure of the primary... requirements of the leak detection component of the secondary containment system are satisfied by installation...

Estimate of the influence of muzzle smoke on function range of infrared system

NASA Astrophysics Data System (ADS)

Luo, Yan-ling; Wang, Jun; Wu, Jiang-hui; Wu, Jun; Gao, Meng; Gao, Fei; Zhao, Yu-jie; Zhang, Lei

2013-09-01

Muzzle smoke produced by weapons shooting has important influence on infrared (IR) system while detecting targets. Based on the theoretical model of detecting spot targets and surface targets of IR system while there is muzzle smoke, the function range for detecting spot targets and surface targets are deduced separately according to the definition of noise equivalent temperature difference(NETD) and minimum resolution temperature difference(MRTD). Also parameters of muzzle smoke affecting function range of IR system are analyzed. Base on measured data of muzzle smoke for single shot, the function range of an IR system for detecting typical targets are calculated separately while there is muzzle smoke and there is no muzzle smoke at 8-12 micron waveband. For our IR system function range has reduced by over 10% for detecting tank if muzzle smoke exists. The results will provide evidence for evaluating the influence of muzzle smoke on IR system and will help researchers to improve ammo craftwork.

Design of DroDeASys (Drowsy Detection and Alarming System)

NASA Astrophysics Data System (ADS)

Juvale, Hrishikesh B.; Mahajan, Anant S.; Bhagwat, Ashwin A.; Badiger, Vishal T.; Bhutkar, Ganesh D.; Dhabe, Priyadarshan S.; Dhore, Manikrao L.

The paper discusses the Drowsy Detection & Alarming System that has been developed, using a non-intrusive approach. The system is basically developed to detect drivers dozing at the wheel at night time driving. The system uses a small infra-red night vision camera that points directly towards the driver`s face and monitors the driver`s eyes in order to detect fatigue. In such a case when fatigue is detected, a warning signal is issued to alert the driver. This paper discusses the algorithms that have been used to detect drowsiness. The decision whether the driver is dozing or not is taken depending on whether the eyes are open for a specific number of frames. If the eyes are found to be closed for a certain number of consecutive frames then the driver is alerted with an alarm.

Microwave frequency sensor for detection of biological cells in microfluidic channels.

PubMed

Nikolic-Jaric, M; Romanuik, S F; Ferrier, G A; Bridges, G E; Butler, M; Sunley, K; Thomson, D J; Freeman, M R

2009-08-12

We present details of an apparatus for capacitive detection of biomaterials in microfluidic channels operating at microwave frequencies where dielectric effects due to interfacial polarization are minimal. A circuit model is presented, which can be used to adapt this detection system for use in other microfluidic applications and to identify ones where it would not be suitable. The detection system is based on a microwave coupled transmission line resonator integrated into an interferometer. At 1.5 GHz the system is capable of detecting changes in capacitance of 650 zF with a 50 Hz bandwidth. This system is well suited to the detection of biomaterials in a variety of suspending fluids, including phosphate-buffered saline. Applications involving both model particles (polystyrene microspheres) and living cells-baker's yeast (Saccharomyces cerevisiae) and Chinese hamster ovary cells-are presented.

Toward detection of marine vehicles on horizon from buoy camera

NASA Astrophysics Data System (ADS)

Fefilatyev, Sergiy; Goldgof, Dmitry B.; Langebrake, Lawrence

2007-10-01

This paper presents a new technique for automatic detection of marine vehicles in open sea from a buoy camera system using computer vision approach. Users of such system include border guards, military, port safety and flow management, sanctuary protection personnel. The system is intended to work autonomously, taking images of the surrounding ocean surface and analyzing them on the subject of presence of marine vehicles. The goal of the system is to detect an approximate window around the ship and prepare the small image for transmission and human evaluation. The proposed computer vision-based algorithm combines horizon detection method with edge detection and post-processing. The dataset of 100 images is used to evaluate the performance of proposed technique. We discuss promising results of ship detection and suggest necessary improvements for achieving better performance.

Syndromic surveillance for health information system failures: a feasibility study.

PubMed

Ong, Mei-Sing; Magrabi, Farah; Coiera, Enrico

2013-05-01

To explore the applicability of a syndromic surveillance method to the early detection of health information technology (HIT) system failures. A syndromic surveillance system was developed to monitor a laboratory information system at a tertiary hospital. Four indices were monitored: (1) total laboratory records being created; (2) total records with missing results; (3) average serum potassium results; and (4) total duplicated tests on a patient. The goal was to detect HIT system failures causing: data loss at the record level; data loss at the field level; erroneous data; and unintended duplication of data. Time-series models of the indices were constructed, and statistical process control charts were used to detect unexpected behaviors. The ability of the models to detect HIT system failures was evaluated using simulated failures, each lasting for 24 h, with error rates ranging from 1% to 35%. In detecting data loss at the record level, the model achieved a sensitivity of 0.26 when the simulated error rate was 1%, while maintaining a specificity of 0.98. Detection performance improved with increasing error rates, achieving a perfect sensitivity when the error rate was 35%. In the detection of missing results, erroneous serum potassium results and unintended repetition of tests, perfect sensitivity was attained when the error rate was as small as 5%. Decreasing the error rate to 1% resulted in a drop in sensitivity to 0.65-0.85. Syndromic surveillance methods can potentially be applied to monitor HIT systems, to facilitate the early detection of failures.

Improved performance comparisons of radioxenon systems for low level releases in nuclear explosion monitoring.

PubMed

Haas, Derek A; Eslinger, Paul W; Bowyer, Theodore W; Cameron, Ian M; Hayes, James C; Lowrey, Justin D; Miley, Harry S

2017-11-01

The Comprehensive Nuclear-Test-Ban Treaty bans all nuclear tests and mandates development of verification measures to detect treaty violations. One verification measure is detection of radioactive xenon isotopes produced in the fission of actinides. The International Monitoring System (IMS) currently deploys automated radioxenon systems that can detect four radioxenon isotopes. Radioxenon systems with lower detection limits are currently in development. Historically, the sensitivity of radioxenon systems was measured by the minimum detectable concentration for each isotope. In this paper we analyze the response of radioxenon systems using rigorous metrics in conjunction with hypothetical representative releases indicative of an underground nuclear explosion instead of using only minimum detectable concentrations. Our analyses incorporate the impact of potential spectral interferences on detection limits and the importance of measuring isotopic ratios of the relevant radioxenon isotopes in order to improve discrimination from background sources particularly for low-level releases. To provide a sufficient data set for analysis, hypothetical representative releases are simulated every day from the same location for an entire year. The performance of three types of samplers are evaluated assuming they are located at 15 IMS radionuclide stations in the region of the release point. The performance of two IMS-deployed samplers and a next-generation system is compared with proposed metrics for detection and discrimination using representative releases from the nuclear test site used by the Democratic People's Republic of Korea. Copyright © 2017 Elsevier Ltd. All rights reserved.

A hierarchical detection method in external communication for self-driving vehicles based on TDMA.

PubMed

Alheeti, Khattab M Ali; Al-Ani, Muzhir Shaban; McDonald-Maier, Klaus

2018-01-01

Security is considered a major challenge for self-driving and semi self-driving vehicles. These vehicles depend heavily on communications to predict and sense their external environment used in their motion. They use a type of ad hoc network termed Vehicular ad hoc networks (VANETs). Unfortunately, VANETs are potentially exposed to many attacks on network and application level. This paper, proposes a new intrusion detection system to protect the communication system of self-driving cars; utilising a combination of hierarchical models based on clusters and log parameters. This security system is designed to detect Sybil and Wormhole attacks in highway usage scenarios. It is based on clusters, utilising Time Division Multiple Access (TDMA) to overcome some of the obstacles of VANETs such as high density, high mobility and bandwidth limitations in exchanging messages. This makes the security system more efficient, accurate and capable of real time detection and quick in identification of malicious behaviour in VANETs. In this scheme, each vehicle log calculates and stores different parameter values after receiving the cooperative awareness messages from nearby vehicles. The vehicles exchange their log data and determine the difference between the parameters, which is utilised to detect Sybil attacks and Wormhole attacks. In order to realize efficient and effective intrusion detection system, we use the well-known network simulator (ns-2) to verify the performance of the security system. Simulation results indicate that the security system can achieve high detection rates and effectively detect anomalies with low rate of false alarms.

Peripheral detection and resolution with mid-/long-wavelength and short-wavelength sensitive cone systems.

PubMed

Zhu, Hai-Feng; Zele, Andrew J; Suheimat, Marwan; Lambert, Andrew J; Atchison, David A

2016-08-01

This study compared neural resolution and detection limits of the human mid-/long-wavelength and short-wavelength cone systems with anatomical estimates of photoreceptor and retinal ganglion cell spacings and sizes. Detection and resolution limits were measured from central fixation out to 35° eccentricity across the horizontal visual field using a modified Lotmar interferometer. The mid-/long-wavelength cone system was studied using a green (550 nm) test stimulus to which S-cones have low sensitivity. To bias resolution and detection to the short-wavelength cone system, a blue (450 nm) test stimulus was presented against a bright yellow background that desensitized the M- and L-cones. Participants were three trichromatic males with normal visual functions. With green stimuli, resolution showed a steep central-peripheral gradient that was similar between participants, whereas the detection gradient was shallower and patterns were different between participants. Detection and resolution with blue stimuli were poorer than for green stimuli. The detection of blue stimuli was superior to resolution across the horizontal visual field and the patterns were different between participants. The mid-/long-wavelength cone system's resolution is limited by midget ganglion cell spacing and its detection is limited by the size of the M- and L-cone photoreceptors, consistent with previous observations. We found that no such simple relationships occur for the short-wavelength cone system between resolution and the bistratified ganglion cell spacing, nor between detection and the S-cone photoreceptor sizes.

Multiple pedestrian detection using IR LED stereo camera

NASA Astrophysics Data System (ADS)

Ling, Bo; Zeifman, Michael I.; Gibson, David R. P.

2007-09-01

As part of the U.S. Department of Transportations Intelligent Vehicle Initiative (IVI) program, the Federal Highway Administration (FHWA) is conducting R&D in vehicle safety and driver information systems. There is an increasing number of applications where pedestrian monitoring is of high importance. Visionbased pedestrian detection in outdoor scenes is still an open challenge. People dress in very different colors that sometimes blend with the background, wear hats or carry bags, and stand, walk and change directions unpredictably. The background is various, containing buildings, moving or parked cars, bicycles, street signs, signals, etc. Furthermore, existing pedestrian detection systems perform only during daytime, making it impossible to detect pedestrians at night. Under FHWA funding, we are developing a multi-pedestrian detection system using IR LED stereo camera. This system, without using any templates, detects the pedestrians through statistical pattern recognition utilizing 3D features extracted from the disparity map. A new IR LED stereo camera is being developed, which can help detect pedestrians during daytime and night time. Using the image differencing and denoising, we have also developed new methods to estimate the disparity map of pedestrians in near real time. Our system will have a hardware interface with the traffic controller through wireless communication. Once pedestrians are detected, traffic signals at the street intersections will change phases to alert the drivers of approaching vehicles. The initial test results using images collected at a street intersection show that our system can detect pedestrians in near real time.

Fault recovery for real-time, multi-tasking computer system

NASA Technical Reports Server (NTRS)

Hess, Richard (Inventor); Kelly, Gerald B. (Inventor); Rogers, Randy (Inventor); Stange, Kent A. (Inventor)

2011-01-01

System and methods for providing a recoverable real time multi-tasking computer system are disclosed. In one embodiment, a system comprises a real time computing environment, wherein the real time computing environment is adapted to execute one or more applications and wherein each application is time and space partitioned. The system further comprises a fault detection system adapted to detect one or more faults affecting the real time computing environment and a fault recovery system, wherein upon the detection of a fault the fault recovery system is adapted to restore a backup set of state variables.

40 CFR 270.21 - Specific part B information requirements for landfills.

Code of Federal Regulations, 2013 CFR

2013-07-01

... surface water at any future time; (ii) The double liner and leak (leachate) detection, collection, and... system, leachate collection and removal system, leak detection system, cover system, and appurtenances...

40 CFR 270.21 - Specific part B information requirements for landfills.

Code of Federal Regulations, 2012 CFR

2012-07-01

... surface water at any future time; (ii) The double liner and leak (leachate) detection, collection, and... system, leachate collection and removal system, leak detection system, cover system, and appurtenances...

40 CFR 270.21 - Specific part B information requirements for landfills.

Code of Federal Regulations, 2011 CFR

2011-07-01

... surface water at any future time; (ii) The double liner and leak (leachate) detection, collection, and... system, leachate collection and removal system, leak detection system, cover system, and appurtenances...

40 CFR 270.21 - Specific part B information requirements for landfills.

Code of Federal Regulations, 2014 CFR

2014-07-01

... surface water at any future time; (ii) The double liner and leak (leachate) detection, collection, and... system, leachate collection and removal system, leak detection system, cover system, and appurtenances...

Detection and treatment of chemical weapons and/or biological pathogens

DOEpatents

Mariella Jr., Raymond P.

2004-09-07

A system for detection and treatment of chemical weapons and/or biological pathogens uses a detector system, an electrostatic precipitator or scrubber, a circulation system, and a control. The precipitator or scrubber is activated in response to a signal from the detector upon the detection of chemical weapons and/or biological pathogens.

40 CFR 63.7830 - What are my monitoring requirements?

Code of Federal Regulations, 2010 CFR

2010-07-01

...) of this section. (1) Install, operate, and maintain a bag leak detection system according to § 63... § 63.7832; or (2) If you do not install and operate a bag leak detection system, you must install... bag leak detection system and COMS are not required for a baghouse that meets the requirements in...

Detection of Structural Abnormalities Using Neural Nets

NASA Technical Reports Server (NTRS)

Zak, M.; Maccalla, A.; Daggumati, V.; Gulati, S.; Toomarian, N.

1996-01-01

This paper describes a feed-forward neural net approach for detection of abnormal system behavior based upon sensor data analyses. A new dynamical invariant representing structural parameters of the system is introduced in such a way that any structural abnormalities in the system behavior are detected from the corresponding changes to the invariant.

40 CFR 63.10899 - What are my recordkeeping and reporting requirements?

Code of Federal Regulations, 2011 CFR

2011-07-01

... of each inspection, and the results of any maintenance performed on the bag filters. (ii) The date... applicable, you must keep records for bag leak detection systems as follows: (i) Records of the bag leak detection system output; (ii) Records of bag leak detection system adjustments, including the date and time...

Overseas testing of a multisensor landmine detection system: results and lessons learned

NASA Astrophysics Data System (ADS)

Keranen, Joe G.; Topolosky, Zeke

2009-05-01

The Nemesis detection system has been developed to provide an efficient and reliable unmanned, multi-sensor, groundbased platform to detect and mark landmines. The detection system consists of two detection sensor arrays: a Ground Penetrating Synthetic Aperture Radar (GPSAR) developed by Planning Systems, Inc. (PSI) and an electromagnetic induction (EMI) sensor array developed by Minelab Electronics, PTY. Limited. Under direction of the Night Vision and Electronic Sensors Directorate (NVESD), overseas testing was performed at Kampong Chhnang Test Center (KCTC), Cambodia, from May 12-30, 2008. Test objectives included: evaluation of detection performance, demonstration of real-time visualization and alarm generation, and evaluation of system operational efficiency. Testing was performed on five sensor test lanes, each consisting of a unique soil mixture and three off-road lanes which include curves, overgrowth, potholes, and non-uniform lane geometry. In this paper, we outline the test objectives, procedures, results, and lessons learned from overseas testing. We also describe the current state of the system, and plans for future enhancements and modifications including clutter rejection and feature-level fusion.

Novel vehicle detection system based on stacked DoG kernel and AdaBoost

PubMed Central

Kang, Hyun Ho; Lee, Seo Won; You, Sung Hyun

2018-01-01

This paper proposes a novel vehicle detection system that can overcome some limitations of typical vehicle detection systems using AdaBoost-based methods. The performance of the AdaBoost-based vehicle detection system is dependent on its training data. Thus, its performance decreases when the shape of a target differs from its training data, or the pattern of a preceding vehicle is not visible in the image due to the light conditions. A stacked Difference of Gaussian (DoG)–based feature extraction algorithm is proposed to address this issue by recognizing common characteristics, such as the shadow and rear wheels beneath vehicles—of vehicles under various conditions. The common characteristics of vehicles are extracted by applying the stacked DoG shaped kernel obtained from the 3D plot of an image through a convolution method and investigating only certain regions that have a similar patterns. A new vehicle detection system is constructed by combining the novel stacked DoG feature extraction algorithm with the AdaBoost method. Experiments are provided to demonstrate the effectiveness of the proposed vehicle detection system under different conditions. PMID:29513727

Interference Information Based Power Control for Cognitive Radio with Multi-Hop Cooperative Sensing

NASA Astrophysics Data System (ADS)

Yu, Youngjin; Murata, Hidekazu; Yamamoto, Koji; Yoshida, Susumu

Reliable detection of other radio systems is crucial for systems that share the same frequency band. In wireless communication channels, there is uncertainty in the received signal level due to multipath fading and shadowing. Cooperative sensing techniques in which radio stations share their sensing information can improve the detection probability of other systems. In this paper, a new cooperative sensing scheme that reduces the false detection probability while maintaining the outage probability of other systems is investigated. In the proposed system, sensing information is collected using multi-hop transmission from all sensing stations that detect other systems, and transmission decisions are based on the received sensing information. The proposed system also controls the transmit power based on the received CINRs from the sensing stations. Simulation results reveal that the proposed system can reduce the outage probability of other systems, or improve its link success probability.

A novel method about detecting missing holes on the motor carling

NASA Astrophysics Data System (ADS)

Xu, Hongsheng; Tan, Hao; Li, Guirong

2018-03-01

After a deep analysis on how to use an image processing system to detect the missing holes on the motor carling, we design the whole system combined with the actual production conditions of the motor carling. Afterwards we explain the whole system's hardware and software in detail. We introduce the general functions for the system's hardware and software. Analyzed these general functions, we discuss the modules of the system's hardware and software and the theory to design these modules in detail. The measurement to confirm the area to image processing, edge detection, randomized Hough transform to circle detecting is explained in detail. Finally, the system result tested in the laboratory and in the factory is given out.

An integrated knowledge system for the Space Shuttle hazardous gas detection system

NASA Technical Reports Server (NTRS)

Lo, Ching F.; Shi, George Z.; Bangasser, Carl; Fensky, Connie; Cegielski, Eric; Overbey, Glenn

1993-01-01

A computer-based integrated Knowledge-Based System, the Intelligent Hypertext Manual (IHM), was developed for the Space Shuttle Hazardous Gas Detection System (HGDS) at NASA Marshall Space Flight Center (MSFC). The IHM stores HGDS related knowledge and presents it in an interactive and intuitive manner. This manual is a combination of hypertext and an expert system which store experts' knowledge and experience in hazardous gas detection and analysis. The IHM's purpose is to provide HGDS personnel with the capabilities of: locating applicable documentation related to procedures, constraints, and previous fault histories; assisting in the training of personnel; enhancing the interpretation of real time data; and recognizing and identifying possible faults in the Space Shuttle sub-systems related to hazardous gas detection.

A Real-Time System for Lane Detection Based on FPGA and DSP

NASA Astrophysics Data System (ADS)

Xiao, Jing; Li, Shutao; Sun, Bin

2016-12-01

This paper presents a real-time lane detection system including edge detection and improved Hough Transform based lane detection algorithm and its hardware implementation with field programmable gate array (FPGA) and digital signal processor (DSP). Firstly, gradient amplitude and direction information are combined to extract lane edge information. Then, the information is used to determine the region of interest. Finally, the lanes are extracted by using improved Hough Transform. The image processing module of the system consists of FPGA and DSP. Particularly, the algorithms implemented in FPGA are working in pipeline and processing in parallel so that the system can run in real-time. In addition, DSP realizes lane line extraction and display function with an improved Hough Transform. The experimental results show that the proposed system is able to detect lanes under different road situations efficiently and effectively.

SSME propellant path leak detection real-time

NASA Technical Reports Server (NTRS)

Crawford, R. A.; Smith, L. M.

1994-01-01

Included are four documents that outline the technical aspects of the research performed on NASA Grant NAG8-140: 'A System for Sequential Step Detection with Application to Video Image Processing'; 'Leak Detection from the SSME Using Sequential Image Processing'; 'Digital Image Processor Specifications for Real-Time SSME Leak Detection'; and 'A Color Change Detection System for Video Signals with Applications to Spectral Analysis of Rocket Engine Plumes'.

Submarine Combat Systems Engineering Project Capstone Project

DTIC Science & Technology

2011-06-06

sonar , imaging, Electronic Surveillance (ES) and communications. These sensors passively detect contacts, which emit... passive sensors is included. A Search Detect Identify Track Decide Engage Assess 3 contact can be sensed by the system as either surface or... Detect Track Avoid Search Detect Identify Track Search Engage Assess Detect Track Avoid Search • SONAR •Imagery •TC • SONAR • SONAR •EW •Imagery •ESM

A CO trace gas detection system based on continuous wave DFB-QCL

NASA Astrophysics Data System (ADS)

Dang, Jingmin; Yu, Haiye; Sun, Yujing; Wang, Yiding

2017-05-01

A compact and mobile system was demonstrated for the detection of carbon monoxide (CO) at trace level. This system adopted a high-power, continuous wave (CW), distributed feedback quantum cascade laser (DFB-QCL) operating at ∼22 °C as excitation source. Wavelength modulation spectroscopy (WMS) as well as second harmonic detection was used to isolate complex, overlapping spectral absorption features typical of ambient pressures and to achieve excellent specificity and high detection sensitivity. For the selected P(11) absorption line of CO molecule, located at 2099.083 cm-1, a limit of detection (LoD) of 26 ppb by volume (ppbv) at atmospheric pressure was achieved with a 1 s acquisition time. Allan deviation analysis was performed to investigate the long term performance of the CO detection system, and a measurement precision of 3.4 ppbv was observed with an optimal integration time of approximate 114 s, which verified the reliable and robust operation of the developed system.

Modeling and Investigation of Heavy Oxide and Alkali-Halide Scintillators for Potential Use in Neutron and Gamma Detection Systems

DTIC Science & Technology

2015-06-01

INVESTIGATION OF HEAVY OXIDE AND ALKALI-HALIDE SCINTILLATORS FOR POTENTIAL USE IN NEUTRON AND GAMMA DETECTION SYSTEMS by Jeremy S. Cadiente June...AND ALKALI- HALIDE SCINTILLATORS FOR POTENTIAL USE IN NEUTRON AND GAMMA DETECTION SYSTEMS 5. FUNDING NUMBERS 6. AUTHOR(S) Jeremy S. Cadiente 7...fast neutron detection efficiencies well over 40%, were investigated for potential use as highly efficient gamma- neutron radiation detectors. The

System Detects Vibrational Instabilities

NASA Technical Reports Server (NTRS)

Bozeman, Richard J., Jr.

1990-01-01

Sustained vibrations at two critical frequencies trigger diagnostic response or shutdown. Vibration-analyzing electronic system detects instabilities of combustion in rocket engine. Controls pulse-mode firing of engine and identifies vibrations above threshold amplitude at 5.9 and/or 12kHz. Adapted to other detection and/or control schemes involving simultaneous real-time detection of signals above or below preset amplitudes at two or more specified frequencies. Potential applications include rotating machinery and encoders and decoders in security systems.

Insulation detection of electric vehicle batteries

NASA Astrophysics Data System (ADS)

Dai, Qiqi; Zhu, Zhongwen; Huang, Denggao; Du, Mingxing; Wei, Kexin

2018-06-01

In this paper, an electric vehicle insulation detection method with single side switching fixed resistance is designed, and the hardware and software design of the system are given. The experiment proves that the insulation detection system can detect the insulation resistance in a wide range of resistance values, and accurately report the fault level. This system can effectively monitor the insulation fault between the car body and the high voltage line and avoid the passengers from being injured.

Chemical contamination remote sensing

NASA Technical Reports Server (NTRS)

Carrico, J. P.; Phelps, K. R.; Webb, E. N.; Mackay, R. A.; Murray, E. R.

1986-01-01

A ground mobile laser test bed system was assembled to assess the feasibility of detection of various types of chemical contamination using Differential Scattering (DISC) and Differential Absorption (DIAL) Lidar techniques. Field experiments with the test bed system using chemical simulants were performed. Topographic reflection and range resolved DIAL detection of vapors as well as DISC detection of aerosols and surface contamination were achieved. Review of detection principles, design of the test bed system, and results of the experiments are discussed.

Astrometric detectability of systems with unseen companions: effects of the Earth orbital motion

NASA Astrophysics Data System (ADS)

Butkevich, Alexey G.

2018-06-01

The astrometric detection of an unseen companion is based on an analysis of the apparent motion of its host star around the system's barycentre. Systems with an orbital period close to 1 yr may escape detection if the orbital motion of their host stars is observationally indistinguishable from the effects of parallax. Additionally, an astrometric solution may produce a biased parallax estimation for such systems. We examine the effects of the orbital motion of the Earth on astrometric detectability in terms of a correlation between the Earth's orbital position and the position of the star relative to its system barycentre. The χ2 statistic for parallax estimation is calculated analytically, leading to expressions that relate the decrease in detectability and accompanying parallax bias to the position correlation function. The impact of the Earth's motion critically depends on the exoplanet's orbital period, diminishing rapidly as the period deviates from 1 yr. Selection effects against 1-yr-period systems is, therefore, expected. Statistical estimation shows that the corresponding loss of sensitivity results in a typical 10 per cent increase in the detection threshold. Consideration of eccentric orbits shows that the Earth's motion has no effect on detectability for e≳ 0.5. The dependence of the detectability on other parameters, such as orbital phases and inclination of the orbital plane to the ecliptic, are smooth and monotonic because they are described by simple trigonometric functions.

Requirements for the Development of Bacillus Anthracis Spore Reference Materials Used to Test Detection Systems

PubMed Central

Almeida, Jamie L.; Wang, Lili; Morrow, Jayne B.; Cole, Kenneth D.

2006-01-01

Bacillus anthracis spores have been used as biological weapons and the possibility of their further use requires surveillance systems that can accurately and reliably detect their presence in the environment. These systems must collect samples from a variety of matrices, process the samples, and detect the spores. The processing of the sample may include removal of inhibitors, concentration of the target, and extraction of the target in a form suitable for detection. Suitable reference materials will allow the testing of each of these steps to determine the sensitivity and specificity of the detection systems. The development of uniform and well-characterized reference materials will allow the comparison of different devices and technologies as well as assure the continued performance of detection systems. This paper discusses the special requirements of reference materials for Bacillus anthracis spores that could be used for testing detection systems. The detection of Bacillus anthracis spores is based on recognition of specific characteristics (markers) on either the spore surface or in the nucleic acids (DNA). We have reviewed the specific markers and their relevance to characterization of reference materials. We have also included the approach for the characterization of candidate reference materials that we are developing at the NIST laboratories. Additional applications of spore reference materials would include testing sporicidal treatments, techniques for sampling the environment, and remediation of spore-contaminated environments. PMID:27274929

Neural adaptive observer-based sensor and actuator fault detection in nonlinear systems: Application in UAV.

PubMed

Abbaspour, Alireza; Aboutalebi, Payam; Yen, Kang K; Sargolzaei, Arman

2017-03-01

A new online detection strategy is developed to detect faults in sensors and actuators of unmanned aerial vehicle (UAV) systems. In this design, the weighting parameters of the Neural Network (NN) are updated by using the Extended Kalman Filter (EKF). Online adaptation of these weighting parameters helps to detect abrupt, intermittent, and incipient faults accurately. We apply the proposed fault detection system to a nonlinear dynamic model of the WVU YF-22 unmanned aircraft for its evaluation. The simulation results show that the new method has better performance in comparison with conventional recurrent neural network-based fault detection strategies. Copyright © 2016 ISA. Published by Elsevier Ltd. All rights reserved.

Video copy protection and detection framework (VPD) for e-learning systems

NASA Astrophysics Data System (ADS)

ZandI, Babak; Doustarmoghaddam, Danial; Pour, Mahsa R.

2013-03-01

This Article reviews and compares the copyright issues related to the digital video files, which can be categorized as contended based and Digital watermarking copy Detection. Then we describe how to protect a digital video by using a special Video data hiding method and algorithm. We also discuss how to detect the copy right of the file, Based on expounding Direction of the technology of the video copy detection, and Combining with the own research results, brings forward a new video protection and copy detection approach in terms of plagiarism and e-learning systems using the video data hiding technology. Finally we introduce a framework for Video protection and detection in e-learning systems (VPD Framework).

A Protocol Specification-Based Intrusion Detection System for VoIP and Its Evaluation

NASA Astrophysics Data System (ADS)

Phit, Thyda; Abe, Kôki

We propose an architecture of Intrusion Detection System (IDS) for VoIP using a protocol specification-based detection method to monitor the network traffics and alert administrator for further analysis of and response to suspicious activities. The protocol behaviors and their interactions are described by state machines. Traffic that behaves differently from the standard specifications are considered to be suspicious. The IDS has been implemented and simulated using OPNET Modeler, and verified to detect attacks. It was found that our system can detect typical attacks within a reasonable amount of delay time.

Performance metrics for state-of-the-art airborne magnetic and electromagnetic systems for mapping and detection of unexploded ordnance

NASA Astrophysics Data System (ADS)

Doll, William E.; Bell, David T.; Gamey, T. Jeffrey; Beard, Les P.; Sheehan, Jacob R.; Norton, Jeannemarie

2010-04-01

Over the past decade, notable progress has been made in the performance of airborne geophysical systems for mapping and detection of unexploded ordnance in terrestrial and shallow marine environments. For magnetometer systems, the most significant improvements include development of denser magnetometer arrays and vertical gradiometer configurations. In prototype analyses and recent Environmental Security Technology Certification Program (ESTCP) assessments using new production systems the greatest sensitivity has been achieved with a vertical gradiometer configuration, despite model-based survey design results which suggest that dense total-field arrays would be superior. As effective as magnetometer systems have proven to be at many sites, they are inadequate at sites where basalts and other ferrous geologic formations or soils produce anomalies that approach or exceed those of target ordnance items. Additionally, magnetometer systems are ineffective where detection of non-ferrous ordnance items is of primary concern. Recent completion of the Battelle TEM-8 airborne time-domain electromagnetic system represents the culmination of nearly nine years of assessment and development of airborne electromagnetic systems for UXO mapping and detection. A recent ESTCP demonstration of this system in New Mexico showed that it was able to detect 99% of blind-seeded ordnance items, 81mm and larger, and that it could be used to map in detail a bombing target on a basalt flow where previous airborne magnetometer surveys had failed. The probability of detection for the TEM-8 in the blind-seeded study area was better than that reported for a dense-array total-field magnetometer demonstration of the same blind-seeded site, and the TEM-8 system successfully detected these items with less than half as many anomaly picks as the dense-array total-field magnetometer system.

Automated accident detection at intersections.

DOT National Transportation Integrated Search

2004-03-01

This research aims to provide a timely and accurate accident detection method at intersections, which is : very important for the Traffic Management System(TMS). This research uses acoustic signals to detect : accident at intersections. A system is c...

Overview of ISS U.S. Fire Detection and Suppression System

NASA Technical Reports Server (NTRS)

Whitaker, Alana

2003-01-01

This paper presents a general overview of the International Space Station's Fire Detection and Suppression System. The topics include: 1) Introduction to Fire Detection and Suppression (FDS); 2) Description of (FDS) Subsystems; 3) FDS System Component Location and Status; 4) FDS System Capabilities; 5) FDS Automatic and Manual Response; 6) Post Fire Atmosphere Restoration and Air Quality Assessment; and 7) FDS Research Needs. This paper is in viewgraph form.

A Context-Aware EEG Headset System for Early Detection of Driver Drowsiness.

PubMed

Li, Gang; Chung, Wan-Young

2015-08-21

Driver drowsiness is a major cause of mortality in traffic accidents worldwide. Electroencephalographic (EEG) signal, which reflects the brain activities, is more directly related to drowsiness. Thus, many Brain-Machine-Interface (BMI) systems have been proposed to detect driver drowsiness. However, detecting driver drowsiness at its early stage poses a major practical hurdle when using existing BMI systems. This study proposes a context-aware BMI system aimed to detect driver drowsiness at its early stage by enriching the EEG data with the intensity of head-movements. The proposed system is carefully designed for low-power consumption with on-chip feature extraction and low energy Bluetooth connection. Also, the proposed system is implemented using JAVA programming language as a mobile application for on-line analysis. In total, 266 datasets obtained from six subjects who participated in a one-hour monotonous driving simulation experiment were used to evaluate this system. According to a video-based reference, the proposed system obtained an overall detection accuracy of 82.71% for classifying alert and slightly drowsy events by using EEG data alone and 96.24% by using the hybrid data of head-movement and EEG. These results indicate that the combination of EEG data and head-movement contextual information constitutes a robust solution for the early detection of driver drowsiness.