van Londen, G J; Beckjord, E B; Dew, M A; Cooper, K L; Davidson, N E; Bovbjerg, D H; Donovan, H S; Thurston, R C; Morse, J Q; Nutt, S; Rechis, R
2014-04-01
Breast cancer survivors often receive long-term adjuvant endocrine therapy (AET) to reduce recurrence risk. Adherence to AET is suboptimal, which may be due to the experience of symptoms and/or concerns. Few studies have comprehensively assessed self-reported concerns between those who currently, previously or have never received AET. The study objective is to describe self-reported physical and emotional concerns of breast cancer survivors who are current, prior, or never-recipients of AET. Secondary analysis was performed on a subset of survey data collected in the 2010 LIVESTRONG Survey. Breast cancer survivors (n = 1,013, mean 5.4 years post-diagnosis) reported on 14 physical and eight emotional concerns that began after diagnosis and were experienced within 6 months of participation in the survey. Bivariate analyses examined the prevalence of each concern by AET status. The relationships between AET and burden of physical or emotional concerns were modeled with logistic regression. More than 50% of the participants reported currently experiencing cognitive issues, fatigue, fear of recurrence, emotional distress, and identity/grief issues. Thyroid dysfunction and stigma concerns were more common among participants with prior AET (p < 0.01), while fear of recurrence, emotional distress, and concern about appearance were more common among those currently receiving AET (p < 0.01). Fatigue, sexual dysfunction, and pain were more common among prior and current AET recipients (p < 0.01). In adjusted models, receipt of AET was associated with a higher number of physical, but not emotional concerns. A higher number of concerns was associated with younger age, having children, receipt of chemotherapy, longer duration of cancer treatment, and shorter time since diagnosis (p < 0.01). Breast cancer survivors who received AET were at risk of developing a variety of physical and emotional concerns, many of which persisted after treatment. These findings suggest the importance of developing individualized, supportive resources for breast cancer survivors.
Augmentative Communication Services in the Schools.
ERIC Educational Resources Information Center
Blackstone, Sarah W.
1989-01-01
The article considers current issues concerning service delivery systems and practices concerning augmentative and alternative communication (AAC) services in U.S. schools. Concerns in AAC program development are noted and service delivery models (center-based, community-based, or collaborative) are compared. (DB)
Individual Educational Programs: Issues and Options for Change. Final Report.
ERIC Educational Resources Information Center
McLaughlin, Margaret J.; And Others
Major issues concerning the Individualized Education Program (IEP) are reviewed and modifications are proposed. The history of the IEP and current legal requirements for developing IEPs are considered. Current issues with the IEP include the cost of development, the lack of parent involvement in IEP development, and the use of the IEP for…
Physical and Cognitive Development in the First Two Years.
ERIC Educational Resources Information Center
Caulfield, Rick
1996-01-01
Reviews current research on infant and toddler physical development, cognitive development, and language acquisition. Provides a list of suggested activities, safety concerns, and opportunities for caregivers to enhance child development. (SD)
ERIC Educational Resources Information Center
Rockel, Jean
2014-01-01
This paper critically examines current concerns regarding professional issues in labour force development for teachers with children up to two years of age (UtoT). The concerns in New Zealand (NZ) relate to whether initial teacher-education (ITE) qualifications prepare teachers to work with children UtoT, involving synergy between ITE and the…
Balancing Scientific Publication and National Security Concerns: Issues for Congress
2003-01-10
because of its potential relevance to biological weapons of mass destruction. Whether the current method of only using classification to limit the...terrorist groups in developing weapons of mass destruction. In 2000, researchers at the Co-operative Research Centre for the Biological Control of Pest...development of chemical, biological , or nuclear weapons is not made accessible to terrorists or countries of proliferation concern. The resolution
Comprehensive Nuclear-Test-Ban Treaty: Background and Current Developments
2008-04-30
resumed testing, and has no plans to test. It has reduced the time needed to conduct a nuclear test. Critics raised concerns about the implications of...lieu of the current treaty.1 On October 24, Senator Jon Kyl delivered a speech critical of the CTBT and of Section 3122 in H.R. 1585, the FY2008...2007. Critics expressed concern about the implications of these policies for testing and new weapons. A statement by Physicians for Social
76 FR 45651 - Proposed Collection; Comment Request
Federal Register 2010, 2011, 2012, 2013, 2014
2011-07-29
... DEPARTMENT OF THE TREASURY Community Development Financial Institutions Fund Proposed Collection...)). Currently, the Community Development Financial Institutions Fund (the ``CDFI Fund'') within the Department of the Treasury is soliciting comments concerning the Community Development Financial Institutions...
Ruck, Jessica M; Van Pilsum Rasmussen, Sarah E; Henderson, Macey L; Massie, Allan B; Segev, Dorry L
2018-06-08
Efforts are underway to improve living kidney donor (LKD) education, but current LKD concerns and information-gathering preferences have not been ascertained to inform evidence-based resource development. As a result, prior studies have found that donors desire information that is not included in current informed consent and/or educational materials. We conducted semi-structured interviews with 50 LKDs who donated at our center to assess (1) concerns about donation that they either had personally before or after donation or heard from family members or friends, (2) information that they had desired before donation, and (3) where they sought information about donation. We used thematic analysis of verbatim interview transcriptions to identify donation-related concerns. We compared the demographic characteristics of participants reporting specific concerns using Fisher's exact test. We identified 19 unique concerns that participants had or heard about living kidney donation. 20% of participants reported having had no pre-donation concerns; 38% reported no post-donation concerns. The most common concern pre-donation was future kidney failure (22%), post-donation was the recovery process (24%), and from family was endangering their family unit (16%). 44% of participants reported being less concerned than family. 26% of participants wished they had had additional information prior to donating, including practical advice for recovery (10%) and information about specific complications (14%). Caucasian participants were more likely to hear at least one concern from family (76% vs. 33%, p = 0.02). The most commonly consulted educational resources were health care providers (100%) and websites (79% of donors since 2000). 26% of participants had had contact with other donors; an additional 20% desired contact with other LKDs. Potential donors not only have personal donation-related concerns but frequently hear donation-related concerns from family members and friends. Current gaps in donor education include an absence of practical, peer-to-peer advice about donation from other prior donors and materials directed and potential donors' family members and friends. These findings can inform the development of new educational practices and resources targeted not only at LKDs but at their social networks.
Adaptive Variable Bias Magnetic Bearing Control
NASA Technical Reports Server (NTRS)
Johnson, Dexter; Brown, Gerald V.; Inman, Daniel J.
1998-01-01
Most magnetic bearing control schemes use a bias current with a superimposed control current to linearize the relationship between the control current and the force it delivers. With the existence of the bias current, even in no load conditions, there is always some power consumption. In aerospace applications, power consumption becomes an important concern. In response to this concern, an alternative magnetic bearing control method, called Adaptive Variable Bias Control (AVBC), has been developed and its performance examined. The AVBC operates primarily as a proportional-derivative controller with a relatively slow, bias current dependent, time-varying gain. The AVBC is shown to reduce electrical power loss, be nominally stable, and provide control performance similar to conventional bias control. Analytical, computer simulation, and experimental results are presented in this paper.
Review of Research in Curriculum.
ERIC Educational Resources Information Center
Johnson, Mauritz
This paper examines research concerned with the definition, development, and effects of curriculum. Ten aspects of current curriculum scholarship are examined. The first three (the state of the field, the scope of the field, and the revolt against scientism and rationality) concern curriculum study as a whole. Despite the assessment that the field…
Perspective taking and empathic concern in adolescence: gender differences in developmental changes.
Van der Graaff, Jolien; Branje, Susan; De Wied, Minet; Hawk, Skyler; Van Lier, Pol; Meeus, Wim
2014-03-01
Empathy is an important social skill and is believed to play an essential role in moral development (Hoffman, 2000). In the present longitudinal study, the authors investigated adolescents' development of perspective taking and empathic concern from age 13 to 18 years (mean age at Wave 1 = 13 years, SD = 0.46) and examined its association with pubertal status. Adolescents (283 boys, 214 girls) reported for 6 consecutive years on their dispositional perspective taking and empathic concern and for 4 consecutive years on pubertal status. Latent growth curve modeling revealed gender differences in levels and developmental trends. Gender differences in perspective taking emerged during adolescence, with girls' increases being steeper than those of the boys. Girls also showed higher levels of empathic concern than did boys. Whereas girls' empathic concern remained stable across adolescence, boys showed a decrease from early to middle adolescence with a rebound to the initial level thereafter. Boys who were physically more mature also reported lower empathic concern than did their less physically developed peers. The current study supports theoretical notions that perspective taking develops during adolescence as a result of cognitive development. Moreover, the results suggest that pubertal maturation plays a role in boys' development of empathic concern. PsycINFO Database Record (c) 2014 APA, all rights reserved.
A multi-machine scaling of halo current rotation
NASA Astrophysics Data System (ADS)
Myers, C. E.; Eidietis, N. W.; Gerasimov, S. N.; Gerhardt, S. P.; Granetz, R. S.; Hender, T. C.; Pautasso, G.; Contributors, JET
2018-01-01
Halo currents generated during unmitigated tokamak disruptions are known to develop rotating asymmetric features that are of great concern to ITER because they can dynamically amplify the mechanical stresses on the machine. This paper presents a multi-machine analysis of these phenomena. More specifically, data from C-Mod, NSTX, ASDEX Upgrade, DIII-D, and JET are used to develop empirical scalings of three key quantities: (1) the machine-specific minimum current quench time, \
A multi-machine scaling of halo current rotation
DOE Office of Scientific and Technical Information (OSTI.GOV)
Myers, C. E.; Eidietis, N. W.; Gerasimov, S. N.
Halo currents generated during unmitigated tokamak disruptions are known to develop rotating asymmetric features that are of great concern to ITER because they can dynamically amplify the mechanical stresses on the machine. This paper presents a multi-machine analysis of these phenomena. More specifically, data from C-Mod, NSTX, ASDEX Upgrade, DIII-D, and JET are used to develop empirical scalings of three key quantities: the machine-specific minimum current quench time,more » $$ \
A multi-machine scaling of halo current rotation
Myers, C. E.; Eidietis, N. W.; Gerasimov, S. N.; ...
2017-12-12
Halo currents generated during unmitigated tokamak disruptions are known to develop rotating asymmetric features that are of great concern to ITER because they can dynamically amplify the mechanical stresses on the machine. This paper presents a multi-machine analysis of these phenomena. More specifically, data from C-Mod, NSTX, ASDEX Upgrade, DIII-D, and JET are used to develop empirical scalings of three key quantities: the machine-specific minimum current quench time,more » $$ \
The Development of an Elementary School Student Handbook.
ERIC Educational Resources Information Center
Aaland, Janine; And Others
One of the challenges facing school systems is creating an effective student handbook of current school policies. This report reviews the literature concerning federal and state statutes, district policies, and the professional literature concerning the implementation of a school wide discipline policy and plan that can be codified in a handbook.…
Cole, Scott N; Berntsen, Dorthe
2016-01-01
Our overriding hypothesis was that future thinking would be linked with goals to a greater extent than memories; conceptualizing goals as current concerns (i.e., uncompleted personal goals). We also hypothesized that current-concern-related events would differ from non-current-concern-related events on a set of phenomenological characteristics. We report novel data from a study examining involuntary and voluntary mental time travel using an adapted laboratory paradigm. Specifically, after autobiographical memories or future thoughts were elicited (between participants) in an involuntary and voluntary retrieval mode (within participants), participants self-generated five current concerns and decided whether each event was relevant or not to their current concerns. Consistent with our hypothesis, compared with memories, a larger percentage of involuntary and voluntary future thoughts reflected current concerns. Furthermore, events related to current concerns differed from non-concern-related events on a range of cognitive, representational, and affective phenomenological measures. These effects were consistent across temporal direction. In general, our results agree with the proposition that involuntary and voluntary future thinking is important for goal-directed cognition and behaviour.
Developing estimates of potential demand for renewable wood energy products in Alaska
Allen M. Brackley; Valerie A. Barber; Cassie Pinkel
2010-01-01
Goal three of the current U.S. Department of Agriculture, Forest Service strategy for improving the use of woody biomass is to help develop and expand markets for woody biomass products. This report is concerned with the existing volumes of renewable wood energy products (RWEP) that are currently used in Alaska and the potential demand for RWEP for residential and...
Current Topics in Early Childhood Education. Volume II.
ERIC Educational Resources Information Center
Katz, Lilian G., Ed.; And Others
The ten papers in this volume present integrative reviews, analyses and syntheses of research and development of current concern to early childhood educators. Four papers represent investigations and reports of programmatic or educational activities. House and Hutchins critically analyze Abt Associates' national evaluation of Project Follow…
Federal Register 2010, 2011, 2012, 2013, 2014
2010-06-21
...., Asian Star Development, Inc., Associated Golf Management, Inc. (n/k/a Delta Mining & Exploration Corp... of current and accurate information concerning the securities of Asian Star Development, Inc. because...
Rethinking Giftedness and Talent in Sport
ERIC Educational Resources Information Center
Tranckle, Peter; Cushion, Christopher J.
2006-01-01
The purpose of this paper is to understand how gifts are discovered and talents developed within sport. The current literature is critically discussed, highlighting contributions and gaps in current knowledge. Due to issues concerning terminology and the nature versus nurture debate, research on talent faces challenges relating to continuity and…
On the Development of Information Science
ERIC Educational Resources Information Center
Salton, G.
1973-01-01
The citations appearing in two recent comprehensive bibliographies in information science and technology are reviewed, and a comparison is made with bibliographies dating back to 1962. Some conclusions are drawn concerning the development and current state of information science. (5 references) (Author)
Le, Kimdy; Donnellan, M Brent; Conger, Rand
2014-02-01
Investigations concerning adult personality development have increasingly focused on factors that are associated with apparent personality trait changes. The current study contributes to this literature by replicating and extending previous research concerning personality trait development in young adulthood and perceptions of workplace conditions. Analyses were based on up to 442 individuals who participated in the ongoing Family Transitions Project (e.g., Conger & Conger, 2002). The current analyses included personality trait data from 1994 and 2003, high school grades and socioeconomic status indicators from 1994, and reports about work conditions in 2001, 2003, and 2005. Personality attributes were prospectively associated with work conditions and income. Findings also support the corresponsive principle of personality development (e.g., Roberts, Caspi, & Moffitt, 2003): Traits that were prospectively associated with particular workplace conditions often seemed to be accentuated by those conditions. Personality traits are prospectively associated with perceptions of the workplace. Workplace conditions are also associated with trait development. © 2013 Wiley Periodicals, Inc.
Le, Kimdy; Donnellan, M. Brent; Conger, Rand
2013-01-01
Objective Investigations concerning adult personality development have increasingly focused on factors that are associated with apparent personality trait changes. The current study contributes to this literature by replicating and extending previous research concerning personality trait development in young adulthood and perceptions of workplace conditions. Method Analyses were based on up to 442 individuals who participated in the ongoing Family Transitions Project (e.g., Conger & Conger, 2002). The current analyses included personality trait data from 1994 and 2003, high-school grades and SES indicators from 1994, and reports about work conditions in 2001, 2003, and 2005. Results Personality attributes were prospectively associated with work conditions and income. Findings also support the corresponsive principle of personality development (e.g. Roberts, Caspi, & Moffitt, 2003): Traits that were prospectively associated with particular workplace conditions often seemed to be accentuated by those conditions. Conclusions Personality traits are prospectively associated with perceptions of the workplace. Workplace conditions are also associated with trait development. PMID:23336723
ERIC Educational Resources Information Center
Gambrill, Eileen
2016-01-01
The integration of research and practice is of concern in all helping professions. Has social work become an evidence-based profession as some claim? Characteristics of current-day social work are presented that dispute this view, related continuing concerns are suggested, and promising developments (mostly outside social work) are described that…
ERIC Educational Resources Information Center
Thorpe, Anthony; Garside, Diane
2017-01-01
The professional development of middle leaders in higher education is little considered in existing research, though there are general concerns being raised about the suitability of the professional development opportunities currently available. This article develops and explores the use of meta-reflection as a method for professional development,…
Current State and Future Prospects of Education for Sustainable Development (ESD) in Japan
ERIC Educational Resources Information Center
Tanaka, Haruhiko
2017-01-01
The UN Decade of Education for Sustainable Development (ESD) ran from 2005 to 2014. This study concerns the concepts of Sustainable Development (SD) and ESD. The term "sustainable development" was coined by the Brundtland Commission in 1987 as the key word in integrating environment and development. SD achieved international consensus at…
Gruskin, Sofia; Cottingham, Jane; Hilber, Adriane Martin; Kismodi, Eszter; Lincetto, Ornella; Roseman, Mindy Jane
2008-08-01
We describe the historical development of how maternal and neonatal mortality in the developing world came to be seen as a public-health concern, a human rights concern, and ultimately as both, leading to the development of approaches using human rights concepts and methods to advance maternal and neonatal health. We describe the different contributions of the international community, women's health advocates and human rights activists. We briefly present a recent effort, developed by WHO with the Harvard Program on International Health and Human Rights, that applies a human rights framework to reinforce current efforts to reduce maternal and neonatal mortality.
Bauquier, Charlotte; Pannard, Myriam; Préau, Marie
2017-10-02
Community-based research drives innovation in major fields of public health, HIV/AIDS being the most emblematic example (Demange, Henry & Préau, 2012), and hepatitis. However, this type of research appears to be more difficult to develop in certain specific diseases, such as cancer (Shankand, Saïas & Friboulet, 2009). This article proposes various approaches concerning current citizen mobilization in relation to cancer research, including potential new levers to the development of participative and community-based research based on the recent creation of the Seintinelles platform, designed to federate researchers and citizens concerned by the problem of cancer. This reflection will be supported by more global issues concerning health democracy.
Wilks, Matti; Redshaw, Jonathan; Nielsen, Mark
2018-01-01
Prominent theorists have made the argument that modern humans express moral concern for a greater number of entities than at any other time in our past. Moreover, adults show stable patterns in the degrees of concern they afford certain entities over others, yet it remains unknown when and how these patterns of moral decision-making manifest in development. Children aged 4 to 10 years (N = 151) placed 24 pictures of human, animal, and environmental entities on a stratified circle representing three levels of moral concern. Although younger and older children expressed similar overall levels of moral concern, older children demonstrated a more graded understanding of concern by including more entities within the outer reaches of their moral circles (i.e., they were less likely to view moral inclusion as a simple in vs. out binary decision). With age children extended greater concern to humans than other forms of life, and more concern to vulnerable groups, such as the sick and disabled. Notably, children’s level of concern for human entities predicted their prosocial behavior. The current research provides novel insights into the development of our moral reasoning and its structure within childhood. PMID:29813134
Neldner, Karri; Crimston, Daniel; Wilks, Matti; Redshaw, Jonathan; Nielsen, Mark
2018-01-01
Prominent theorists have made the argument that modern humans express moral concern for a greater number of entities than at any other time in our past. Moreover, adults show stable patterns in the degrees of concern they afford certain entities over others, yet it remains unknown when and how these patterns of moral decision-making manifest in development. Children aged 4 to 10 years (N = 151) placed 24 pictures of human, animal, and environmental entities on a stratified circle representing three levels of moral concern. Although younger and older children expressed similar overall levels of moral concern, older children demonstrated a more graded understanding of concern by including more entities within the outer reaches of their moral circles (i.e., they were less likely to view moral inclusion as a simple in vs. out binary decision). With age children extended greater concern to humans than other forms of life, and more concern to vulnerable groups, such as the sick and disabled. Notably, children's level of concern for human entities predicted their prosocial behavior. The current research provides novel insights into the development of our moral reasoning and its structure within childhood.
USSR Report, Political and Sociological Affairs No. 1402.
1983-04-29
party’s current agricultural policy . The party and Soviet bodies, the initial party organizations and leaders of agroindustrial enterprises and...the preparation and education of the cadres so that they correspond with the current agricultural policy of the party. This particularly concerns...agricultural output volume and explains the tasks to speed up the intensive development of production. Our party’s current agricultural policy , which
Appropriate utilization of data from toxicogenomic studies ins an ongoing concern of the regulated industries and the agencies charged with assessing safety or risk. An area of current interest is the possibility of toxicogenomics to enhance our ability to develop higher or high-...
2006-05-01
In addition to NBC concerns, there are issues in many current military settings for exposures to toxic industrial chemicals or materials (TICs or TIMs...Significant health issues caused by use of legacy chemicals have emphasized the need for more effective predication of chemical toxicity . This paper...current military settings for exposures to toxic industrial chemicals or materials (TICs or TIMs). Significant health issues caused by use of legacy
The Fertility Problem Inventory: measuring perceived infertility-related stress.
Newton, C R; Sherrard, W; Glavac, I
1999-07-01
To develop a reliable, valid instrument to evaluate perceived infertility-related stress. Prospective study. University-affiliated teaching hospital. Consecutively referred patients (1,153 women and 1,149 men) seen for infertility treatment. None. Participants' infertility-related stress was assessed by written questionnaire using the Fertility Problem Inventory. Current levels of anxiety, depression, and marital satisfaction also were determined. Women described greater global stress than men and higher specific stress in terms of social concerns, sexual concerns, and need for parenthood. Both men and women facing male infertility reported higher global stress and more social and sexual concerns than men and women experiencing female infertility. Social, sexual, and relationship concerns related to infertility were more effective predictors of depression and marital dissatisfaction than expressed needs for parenthood or attitudes toward child-free living. The Fertility Problem Inventory provides a reliable measure of perceived infertility-related stress and specific information on five separate domains of patient concern. Patterns of infertility-related stress differed depending on gender, fertility history, and infertility diagnosis. Among patients receiving treatment, social, sexual, and relationship concerns appear central to current distress. Counseling interventions that target these domains appear likely to offer maximal therapeutic benefit.
Diffusion of Technical Agricultural Information in Chile.
ERIC Educational Resources Information Center
Brown, Marion Ray
This study examined current thought concerning the role of mass communication in economic development in developing nations; analyzed existing efforts to diffuse agricultural technology in Chile; assessed the effectiveness of various approaches; and tested the effects (primarily on knowledge levels) of an experimental technical information service…
Policies and Initiatives: Reforming Teacher Education in Nigeria
ERIC Educational Resources Information Center
Amadi, Martha Nkechinyere
2012-01-01
Much discussion surrounding educational policy currently is international in character. Governments, policy makers, stakeholders and many international organizations of both developed and developing countries have become concerned with how policies, practices, and outcomes in one country can be compared with those in other countries. Comparative…
ERIC Educational Resources Information Center
Spencer, Natalie F.; Dowden, Angel Riddick
2014-01-01
Gifted African American students are underrepresented and underserved in gifted education. The current article provides an overview of proper identification, racial identity development implications, psycho-social concerns and the importance of family involvement in the development of gifted African American students. A case study is presented to…
Integrated Child Development in Rural China.
ERIC Educational Resources Information Center
Xie, Qing; Young, Mary Eming
Since two thirds of the country's children reside in the countryside, improving child development services in rural areas is one of China's most pressing concerns. This report details the current situation of children in rural and urban China and identifies problems related to child development. The report also presents evidence of the effect of…
Mechanisms of Drug-Resistance in Kinases
Barouch-Bentov, Rina; Sauer, Karsten
2010-01-01
Introduction Because of their important roles in disease and excellent “druggability”, kinases have become the second-largest drug target family. The great success of the BCR-ABL inhibitor imatinib in treating CML illustrates the high potential of kinase inhibitor (KI) therapeutics, but also unveiled a major limitation: the development of drug-resistance. This is a significant concern as KIs reach large patient populations for an expanding array of indications. Areas covered We provide an up-to-date understanding of the mechanisms through which KIs function, and through which cells can become KI-resistant. We review current and future approaches to overcome KI-resistance, focussing on currently approved KIs and KIs in clinical trials. We then discuss approaches to improve KI efficacy and overcome drug-resistance and novel approaches to develop less drug-resistance prone KI-therapeutics. Expert opinion Although drug-resistance is a concern for current KI-therapeutics, recent progress in our understanding of the underlying mechanisms and promising technological advances may overcome this limitation and provide powerful new therapeutics. PMID:21235428
Littleton, Heather; Breitkopf, Carmen Radecki
2008-12-01
Dysmorphic appearance concern encompasses preoccupation with a perceived appearance defect, defect checking and camouflaging, and social avoidance. The current study sought to evaluate the internal consistency, factor structure, and convergent validity of a measure of dysmorphic appearance concern, the Body Image Concern Inventory, as well as evaluate the psychometric properties of a Spanish version of the instrument. Women recruited as part of a reproductive clinic-based clinical trial completed the BICI and other self-report measures of distress. A total of 1043 women completed the measures in English (M=29 years, range=18-55 years) and 573 women completed the measures in Spanish (M=32 years, range=18-55 years). Both the English and Spanish BICI were internally consistent and correlated moderately with measures of current psychological distress (STAI-S, CES-D). Confirmatory factor analyses replicated the measure's proposed factor structure. Applications of the BICI for future research are discussed.
Development and experimental study of oil-free capacitor module for plasma focus device
NASA Astrophysics Data System (ADS)
Sharma, Ravindra Kumar; Sharma, Archana
2017-03-01
This development is concerned with the compact capacitor module for a plasma focus device. Oil-free, non-standard geometry capacitors are designed and developed for high current delivery in sub-microseconds time. Metalized dielectric film based pulse capacitor becomes progressively less viable at currents above 10 kA. It is due to reliability and energy scaling difficulties, based on effects such as vaporization, high resistivity, and end connection. Bipolar electrolytic capacitors are also not preferred due to their limited life and comparatively low peak current delivery. Bi-axially oriented polypropylene (BOPP) film with extended aluminum foil is a combination to deliver moderately high power. But, electrically weak points, relative permittivity, and the edge gap margins have made its adoption difficult. A concept has been developed in lab for implementing the above combination in a less complex and costly manner. This paper concerns the development and testing process techniques for quite different hollow cylindrical, oil-free capacitors (4 μ F , 10 kV, 20 nH). Shot life of 1000 has been experimentally performed on the test bed at its rated energy density level. The technological methods and engineering techniques are now available and utilized for manufacturing and testing of BOPP film based oil-free capacitors.
Development and experimental study of oil-free capacitor module for plasma focus device.
Sharma, Ravindra Kumar; Sharma, Archana
2017-03-01
This development is concerned with the compact capacitor module for a plasma focus device. Oil-free, non-standard geometry capacitors are designed and developed for high current delivery in sub-microseconds time. Metalized dielectric film based pulse capacitor becomes progressively less viable at currents above 10 kA. It is due to reliability and energy scaling difficulties, based on effects such as vaporization, high resistivity, and end connection. Bipolar electrolytic capacitors are also not preferred due to their limited life and comparatively low peak current delivery. Bi-axially oriented polypropylene (BOPP) film with extended aluminum foil is a combination to deliver moderately high power. But, electrically weak points, relative permittivity, and the edge gap margins have made its adoption difficult. A concept has been developed in lab for implementing the above combination in a less complex and costly manner. This paper concerns the development and testing process techniques for quite different hollow cylindrical, oil-free capacitors (4 μF, 10 kV, 20 nH). Shot life of 1000 has been experimentally performed on the test bed at its rated energy density level. The technological methods and engineering techniques are now available and utilized for manufacturing and testing of BOPP film based oil-free capacitors.
Workgroup Report: Public Health Strategies for Reducing Aflatoxin Exposure in Developing Countries
Strosnider, Heather; Azziz-Baumgartner, Eduardo; Banziger, Marianne; Bhat, Ramesh V.; Breiman, Robert; Brune, Marie-Noel; DeCock, Kevin; Dilley, Abby; Groopman, John; Hell, Kerstin; Henry, Sara H.; Jeffers, Daniel; Jolly, Curtis; Jolly, Pauline; Kibata, Gilbert N.; Lewis, Lauren; Liu, Xiumei; Luber, George; McCoy, Leslie; Mensah, Patience; Miraglia, Marina; Misore, Ambrose; Njapau, Henry; Ong, Choon-Nam; Onsongo, Mary T.K.; Page, Samuel W.; Park, Douglas; Patel, Manish; Phillips, Timothy; Pineiro, Maya; Pronczuk, Jenny; Rogers, Helen Schurz; Rubin, Carol; Sabino, Myrna; Schaafsma, Arthur; Shephard, Gordon; Stroka, Joerg; Wild, Christopher; Williams, Jonathan T.; Wilson, David
2006-01-01
Consecutive outbreaks of acute aflatoxicosis in Kenya in 2004 and 2005 caused > 150 deaths. In response, the Centers for Disease Control and Prevention and the World Health Organization convened a workgroup of international experts and health officials in Geneva, Switzerland, in July 2005. After discussions concerning what is known about aflatoxins, the workgroup identified gaps in current knowledge about acute and chronic human health effects of aflatoxins, surveillance and food monitoring, analytic methods, and the efficacy of intervention strategies. The workgroup also identified public health strategies that could be integrated with current agricultural approaches to resolve gaps in current knowledge and ultimately reduce morbidity and mortality associated with the consumption of aflatoxin-contaminated food in the developing world. Four issues that warrant immediate attention were identified: a) quantify the human health impacts and the burden of disease due to aflatoxin exposure; b) compile an inventory, evaluate the efficacy, and disseminate results of ongoing intervention strategies; c) develop and augment the disease surveillance, food monitoring, laboratory, and public health response capacity of affected regions; and d) develop a response protocol that can be used in the event of an outbreak of acute aflatoxicosis. This report expands on the workgroup’s discussions concerning aflatoxin in developing countries and summarizes the findings. PMID:17185282
Developing Tools and Techniques to Increase Communication Effectiveness
NASA Technical Reports Server (NTRS)
Hayes, Linda A.; Peterson, Doug
1997-01-01
The Public Affairs Office (PAO) of the Johnson Space Center (JSC) is responsible for communicating current JSC Space Program activities as well as goals and objectives to the American Public. As part of the 1996 Strategic Communications Plan, a review of PAO' s current communication procedures was conducted. The 1996 Summer Faculty Fellow performed research activities to support this effort by reviewing current research concerning NASA/JSC's customers' perceptions and interests, developing communications tools which enable PAO to more effectively inform JSC customers about the Space Program, and proposing a process for developing and using consistent messages throughout PAO. Note that this research does not attempt to change or influence customer perceptions or interests but, instead, incorporates current customer interests into PAO's communication process.
Safety analysis of interchanges
DOT National Transportation Integrated Search
2007-06-01
The objectives of this research are to synthesize the current state of knowledge concerning the safety assessment of new or modified interchanges; develop a spreadsheet-based computational tool for performing safety assessments of interchanges; and i...
Coast, Joanna; Flynn, Terry; Sutton, Eileen; Al-Janabi, Hareth; Vosper, Jane; Lavender, Sarita; Louviere, Jordan; Peters, Tim
2008-10-01
This paper deals with three concerns about the evaluative framework that is currently dominant within health economics. These concerns are: that the evaluative framework is concerned entirely with health; that the evaluative framework has an individualistic focus on patients alone; and that the methods used to estimate 'health' within the current evaluative framework could be improved both in terms of the generation of descriptive systems and in using valuation methods that rely less on people's ability to express their preferences on a cardinal scale. In exploring these issues the Investigating Choice Experiments for Preferences of Older People (ICEPOP) programme has explicitly focused on both the topic of older people and the methods of discrete choice experiments. A capability index has been developed and attributes for an economic measure of end-of-life care are currently being generated, providing the possibility of extending the evaluative framework beyond health alone. A measure of carer's experience and a framework for extending measurement in end-of-life care to loved ones are both also in development, thus extending the evaluative framework beyond the patient alone. Rigorous qualitative methods employing an iterative approach have been developed for use in constructing attributes, and best-worst scaling has been utilized to reduce task complexity and provide insights into heterogeneity. There are a number of avenues for further research in all these areas, but in particular there is need for greater attention to be paid to the theory underlying the evaluative framework within health economics.
ERIC Educational Resources Information Center
Mannheimer, Steve
2016-01-01
The author of this thought-provoking article joins an impressive cohort of current commentators and scholars united in their concern over the state of the art of reading. Mostly, they are concerned with the sustained, silent, generally solitary process of reading in which the reader is deeply focused on and immersed in the text. Their fear is that…
Trends in Mobile Application Development
NASA Astrophysics Data System (ADS)
Holzer, Adrian; Ondrus, Jan
Major software companies, such as Apple and Google, are disturbing the relatively safe and established actors of the mobile application business. These newcomers have caused significant structural changes by imposing and enforcing their own rules for the future of mobile application development. The implications of these changes do not only concern the mobile network operators and mobile phone manufacturers. This changed environment also brings additional opportunities and constraints for current mobile application developers. Therefore, developers need to assess what their options are and how they can take advantages of these current trends. In this paper, we take a developer’s perspective in order to explore how the structural changes will influence the mobile application development markets. Moreover, we discuss what aspects developers need to take into account in order to position themselves within the current trends.
Environmental contaminants of emerging concern in seafood – European database on contaminant levels
DOE Office of Scientific and Technical Information (OSTI.GOV)
Vandermeersch, Griet, E-mail: griet.vandermeersch@ilvo.vlaanderen.be; Lourenço, Helena Maria; Alvarez-Muñoz, Diana
Marine pollution gives rise to concern not only about the environment itself but also about the impact on food safety and consequently on public health. European authorities and consumers have therefore become increasingly worried about the transfer of contaminants from the marine environment to seafood. So-called “contaminants of emerging concern” are chemical substances for which no maximum levels have been laid down in EU legislation, or substances for which maximum levels have been provided but which require revision. Adequate information on their presence in seafood is often lacking and thus potential risks cannot be excluded. Assessment of food safety issuesmore » related to these contaminants has thus become urgent and imperative. A database ( (www.ecsafeseafooddbase.eu)), containing available information on the levels of contaminants of emerging concern in seafood and providing the most recent data to scientists and regulatory authorities, was developed. The present paper reviews a selection of contaminants of emerging concern in seafood including toxic elements, endocrine disruptors, brominated flame retardants, pharmaceuticals and personal care products, polycyclic aromatic hydrocarbons and derivatives, microplastics and marine toxins. Current status on the knowledge of human exposure, toxicity and legislation are briefly presented and the outcome from scientific publications reporting on the levels of these compounds in seafood is presented and discussed. - Highlights: • Development of a European database regarding contaminants of emerging concern. • Current status on knowledge of human exposure, toxicity and legislation. • Review on the occurrence of contaminants of emerging concern in seafood.« less
Treatment optimization in MS: Canadian MS Working Group updated recommendations.
Freedman, Mark S; Selchen, Daniel; Arnold, Douglas L; Prat, Alexandre; Banwell, Brenda; Yeung, Michael; Morgenthau, David; Lapierre, Yves
2013-05-01
The Canadian Multiple Sclerosis Working Group (CMSWG) developed practical recommendations in 2004 to assist clinicians in optimizing the use of disease-modifying therapies (DMT) in patients with relapsing multiple sclerosis. The CMSWG convened to review how disease activity is assessed, propose a more current approach for assessing suboptimal response, and to suggest a scheme for switching or escalating treatment. Practical criteria for relapses, Expanded Disability Status Scale (EDSS) progression and MRI were developed to classify the clinical level of concern as Low, Medium and High. The group concluded that a change in treatment may be considered in any RRMS patient if there is a high level of concern in any one domain (relapses, progression or MRI), a medium level of concern in any two domains, or a low level of concern in all three domains. These recommendations for assessing treatment response should assist clinicians in making more rational choices in their management of relapsing MS patients.
Lesson Study: Developing a Knowledge Base for Elementary Writing Instruction
ERIC Educational Resources Information Center
McQuitty, Vicki
2011-01-01
Concern about students' writing skills has led to recommendations that elementary teachers receive more professional development in how to teach writing (National Commission on Writing, 2006). However, there is currently little evidence about the knowledge teachers need to teach writing well, and it is therefore difficult for teacher…
Developing Employability Skills: Peer Assessment in Higher Education
ERIC Educational Resources Information Center
Cassidy, Simon
2006-01-01
Purpose: Reports examining graduate employment issues suggest that employers are concerned by the lack of employability skills exhibited by entry-level job applications. It is also suggested that employers consider it the responsibility of educational institutions to develop such skills. The current study seeks to identify peer assessment as a…
Culture and Self in Career Development: Working with American Indians
ERIC Educational Resources Information Center
Juntunen, Cindy L.; Cline, Kara
2010-01-01
The career development concerns of American Indians continue to receive limited attention in the vocational or career literature. To address this deficit, the current article will apply the cultural formulation approach to career counseling with American Indians. This article presents information on factors related to cultural and self-identity…
Consumer Education in Vocational Homemaking Education in Texas. Summary Report.
ERIC Educational Resources Information Center
Texas Tech. Univ., Lubbock. School of Home Economics.
A study examined the perceptions of present and former high school students enrolled in vocational homemaking education courses in Texas concerning the usefulness of consumer education concepts developed in the homemaking education program. Using a project-developed survey instrument, researchers collected data from 490 current and 416 randomly…
Islam and Citizenship Education in Singapore: Challenges and Implications
ERIC Educational Resources Information Center
Tan, Charlene
2007-01-01
The religious diversity of Singapore, coupled with the current phenomenon of Islamic revivalism, makes the management of religion a paramount concern for the Singapore government. By examining the developments of Islam in Singapore, this article explores the challenges and implications these developments have on citizenship education in the…
LWIR and VLWIR detectors development at SOFRADIR for space applications
NASA Astrophysics Data System (ADS)
Terrier, Bertrand; Delannoy, Anne; Chorier, Philippe; Maillard, Magalie; Rubaldo, Laurent
2010-10-01
SOFRADIR is one of the leading companies involved in the development and manufacturing of infrared detectors. Its offer covers the infrared spectrum from visible range (0.4 μm) up to very long wavelength range (15 μm). The need in this last field is driven by space activities, especially by meteorological instruments using imagery or spectrometry. In the frame of Meteosat Third Generation mission, ESA has launched pre-development activities to address the critical equipments for risk reduction. VLWIR detectors for FCI and IRS have been considered as challenging ones and thus SOFRADIR has been involved for manufacturing and testing 2D arrays with long cut-off wavelength (14.9μm at 50K) in order to evaluate their compliance to MTG requirements as far as dark current behaviour, quantum efficiency, photoresponse uniformity, spatial response, operability and reliability are concerned. In parallel, trends of space and tactical applications call for dark current reduction technology in order to improve systems performances in terms of operating temperature and signal to noise ratio. In the frame of its common laboratory DEFIR with CEA-LETI, Sofradir has developed a new MCT p on n technology to answer this need. First demonstrations were made with success (640x512, pitch 15μm and cut-off 9.5μm) and Sofradir is now industrializing this technology in particular for tactical application. Thanks to the communality between space and tactical activity at Sofradir, these results will benefit advantageously also to space activity. In this paper, we present a review of latest Sofradir results concerning LWIR and VLWIR technology. In particular, latest data, concerning development and characterization of generic VLWIR technology up to 15 μm cut-off wavelength, are presented as well as data concerning the promising p on n LWIR technology.
Implementation of a Quality Assurance Review System for the Scalable Development of Online Courses
ERIC Educational Resources Information Center
Ozdemir, Devrim; Loose, Rich
2014-01-01
With the growing demand for quality online education in the US, developing quality online courses and online programs, and more importantly maintaining this quality, have been an inevitable concern for higher education institutes. Current literature on quality assurance in online education mostly focuses on the development of review models and…
Federal Register 2010, 2011, 2012, 2013, 2014
2011-10-24
... Development Corp., and Arcland Energy Corp.; Order of Suspension of Trading October 20, 2011. It appears to... current and accurate information concerning the securities of American Enterprise Development Corp... securities of Arcland Energy Corp. because it has not filed any periodic reports since the period ended April...
The New Agent: A Qualitative Study to Strategically Adapt New Agent Professional Development
ERIC Educational Resources Information Center
Baker, Lauri M.; Hadley, Gregg
2014-01-01
The qualitative study reported here assessed the needs of agents related to new agent professional development to improve the current model. Agents who participated in new agent professional development within the last 5 years were selected to participate in focus groups to determine concerns and continued needs. Agents enjoyed networking and…
78 FR 32696 - China Properties Developments, Inc.; Order of Suspension of Trading
Federal Register 2010, 2011, 2012, 2013, 2014
2013-05-31
... SECURITIES AND EXCHANGE COMMISSION [File No. 500-1] China Properties Developments, Inc.; Order of Suspension of Trading May 29, 2013. It appears to the Securities and Exchange Commission that there is a lack of current and accurate information concerning the securities of China Properties Developments, Inc. because it has not filed any periodic...
Weight Concerns and Use of Cigarettes and E-Cigarettes among Young Adults.
Bennett, Brooke L; Pokhrel, Pallav
2018-05-28
Higher weight concerns have been associated with higher cigarette smoking, particularly among women, partly because smoking is perceived to limit appetite for food. E-cigarettes are increasingly used as an alternative to combustible cigarettes and are widely believed to be less harmful than cigarettes. Currently it is not known whether weight concerns are associated with e-cigarette use among young adults. In this study, we tested the association between weight concerns and cigarette and e-cigarette use and use susceptibility among young adults. Cross-sectional data were collected from college students (N = 470; M age = 20.9; SD = 2.1; 65% women). Results indicated that weight concerns were significantly associated with lifetime and current cigarette smoking status, current cigarette smoking frequency and cigarette use susceptibility (among never smokers), adjusting for demographics variables. Weight concerns were not associated with lifetime or current e-cigarette use status or e-cigarette use susceptibility, adjusting for demographics and cigarette use status. However, higher weight concerns were associated with higher frequency of current e-cigarette use, adjusting for demographic variables and current cigarette smoking frequency. These findings imply that even though weight concerns may not motivate e-cigarette use as strongly as cigarette use, weight concerns may influence higher intensity of e-cigarette use among users.
Elucidating Bioethics with Undergraduates.
ERIC Educational Resources Information Center
Hoskins, Betty B.; Shannon, Thomas A.
1977-01-01
Discusses the importance of developing bioethics programs for undergraduate students. Two aspects are considered: (1) current areas of concern and sources of bibliographic information; and (2) problems encountered in undergraduate projects. A list of references is provided. (HM)
Influenza Vaccines: Unmet Needs and Recent Developments
Noh, Ji Yun
2013-01-01
Influenza is a worldwide public health concern. Since the introduction of trivalent influenza vaccine in 1978, vaccination has been the primary means of prevention and control of influenza. Current influenza vaccines have moderate efficacy, good safety, and acceptable tolerability; however, they have unsatisfactory efficacy in older adults, are dependent on egg supply for production, and are time-consuming to manufacture. This review outlines the unmet medical needs of current influenza vaccines. Recent developments in influenza vaccines are also described. PMID:24475351
ERIC Educational Resources Information Center
Thomas, Charles R.
This document is one of the 5 sections of the Data Element Dictionary developed as part of the WICHE Management Information Systems (MIS) Program. The elements in this section apply to both the current and historical data concerning finance. The purpose of the WICHE MIS Program is to make it possible to derive data which will be truly comparable…
Safety assessment and detection methods of genetically modified organisms.
Xu, Rong; Zheng, Zhe; Jiao, Guanglian
2014-01-01
Genetically modified organisms (GMOs), are gaining importance in agriculture as well as the production of food and feed. Along with the development of GMOs, health and food safety concerns have been raised. These concerns for these new GMOs make it necessary to set up strict system on food safety assessment of GMOs. The food safety assessment of GMOs, current development status of safety and precise transgenic technologies and GMOs detection have been discussed in this review. The recent patents about GMOs and their detection methods are also reviewed. This review can provide elementary introduction on how to assess and detect GMOs.
Garfield, S; Smith, F; Francis, S A; Chalmers, C
2007-06-01
The current study aimed to develop a model of patients' preferences for involvement in decision-making concerning the use of medicines for chronic conditions in the UK and test it in a large representative sample of patients with one of two clinical conditions. Following a structured literature review, an instrument was developed which measured the variables that had been identified as predictors of patients' preferences for involvement in decision making in previous research. Five hundred and sixteen patients with rheumatoid arthritis or type 2 diabetes were recruited from outpatient and primary care clinics and asked to complete the instrument. Multivariate analysis revealed that age, social class and clinical condition were associated with preferences for involvement in decision-making concerning the use of medicines for chronic illness but gender, ethnic group, concerns about medicines, beliefs about necessity of medicines, health status, quality of life and time since diagnosis were not. In total, the fitted model explained only 14% of the variance. This study has demonstrated that current research does not provide a basis for predicting patients' preferences for involvement in decision-making. Building concordant relationships may depend on practitioners developing strategies to establish individuals' preferences for involvement in decision-making as part of the ongoing prescriber-patient relationship.
Safety Concerns Surrounding Quinolone Use in Children
Patel, Karisma; Goldman, Jennifer L.
2016-01-01
Fluoroquinolones are highly effective antibiotics with many desirable pharmacokinetic and pharmacodynamic properties including high bioavailability, large volume of distribution, and a broad spectrum of antimicrobial activity. Despite their attractive profile as anti-infective agents, their use in children is limited, primarily due to safety concerns. In this review we highlight the pharmacological properties of fluoroquinolones and describe their current use in pediatrics. In addition, we provide a comprehensive assessment of the safety data associated with fluoroquinolone use in children. Although permanent or destructive arthropathy remains a significant concern, currently available data demonstrate that arthralgia and arthropathy are relatively uncommon in children and resolve following cessation of fluoroquinolone exposure without resulting in long-term sequelae. The concern for safety and risk of adverse events associated with pediatric fluoroquinolone use is likely driving the limited prescribing of this drug class in pediatrics. However, in adults, fluoroquinolones are the most commonly prescribed broad-spectrum antibiotics, resulting in the development of drug-resistant bacteria that can be challenging to treat effectively. The consequence of misuse and overuse of fluoroquinolones leading to drug resistance is a greater, but frequently overlooked, safety concern that applies to both children and adults and one that should be considered at the point of prescribing. PMID:26865283
Scabies: an ancient global disease with a need for new therapies.
Thomas, Jackson; Peterson, Greg M; Walton, Shelley F; Carson, Christine F; Naunton, Mark; Baby, Kavya E
2015-07-01
Scabies is an ancient disease (documented as far back as 2500 years ago). It affects about 300 million people annually worldwide, and the prevalence is as high as about 60% in Indigenous and Torres Strait Islander children in Australia. This is more than six times the rate seen in the rest of the developed world. Scabies is frequently complicated by bacterial infection leading to the development of skin sores and other more serious consequences such as septicaemia and chronic heart and kidney diseases. This causes a substantial social and economic burden especially in resource poor communities around the world. Very few treatment options are currently available for the management of scabies infection. In this manuscript we briefly discuss the clinical consequences of scabies and the problems found (studies conducted in Australia) with the currently used topical and oral treatments. Current scabies treatment options are fairly ineffective in preventing treatment relapse, inflammatory skin reactions and associated bacterial skin infections. None have ovicidal, antibacterial, anti-inflammatory and/or anti-pruritic properties. Treatments which are currently available for scabies can be problematic with adverse effects and perhaps of greater concern the risk of treatment failure. The development of new chemical entities is doubtful in the near future. Though there may be potential for immunological control, the development of a vaccine or other immunotherapy modalities may be decades away. The emergence of resistance among scabies mites to classical scabicides and ineffectiveness of current treatments (in reducing inflammatory skin reactions and secondary bacterial infections associated with scabies), raise serious concerns regarding current therapy. Treatment adherence difficulties, and safety and efficacy uncertainties in the young and elderly, all signal the need to identify new treatments for scabies.
Conceptual Knowledge Acquisition in Biomedicine: A Methodological Review
Payne, Philip R.O.; Mendonça, Eneida A.; Johnson, Stephen B.; Starren, Justin B.
2007-01-01
The use of conceptual knowledge collections or structures within the biomedical domain is pervasive, spanning a variety of applications including controlled terminologies, semantic networks, ontologies, and database schemas. A number of theoretical constructs and practical methods or techniques support the development and evaluation of conceptual knowledge collections. This review will provide an overview of the current state of knowledge concerning conceptual knowledge acquisition, drawing from multiple contributing academic disciplines such as biomedicine, computer science, cognitive science, education, linguistics, semiotics, and psychology. In addition, multiple taxonomic approaches to the description and selection of conceptual knowledge acquisition and evaluation techniques will be proposed in order to partially address the apparent fragmentation of the current literature concerning this domain. PMID:17482521
Extending the diffuse layer model of surface acidity behavior: I. Model development
Considerable disenchantment exists within the environmental research community concerning our current ability to accurately model surface-complexation-mediated low-porewater-concentration ionic contaminant partitioning with natural surfaces. Several authors attribute this unaccep...
ERIC Educational Resources Information Center
Thomas, Lewis
1981-01-01
Presents a viewpoint concerning the impact of recent scientific advances on society. Discusses biological discoveries, space exploration, computer technology, development of new astronomical theories, the behavioral sciences, and basic research. Challenges to keeping science current with technological advancement are also discussed. (DS)
Principal Concerns in Indiana: Focus on Developing Current Principals. Data Brief
ERIC Educational Resources Information Center
Martin, Katherine; DeArmond, Michael
2012-01-01
Common sense and recent research make it clear that successful schools need strong principals. Strong principals help drive school performance in many ways, from shaping a school's mission and culture to hiring, developing, and retaining good teachers. Even so, principals often get short shrift in today's debates about human capital in public…
A Discrepancy in Teachers and Principals Perceptions of Educational Initiatives
ERIC Educational Resources Information Center
Ifat, Linder; Eyal, Weissblueth
2017-01-01
The current study was set to examine the role of school principals in Israel in the professional development process of their teachers following the implementation of a new professional reform. 159 teachers and 13 principals responded to a questionnaire designed to collect data concerning the involvement of principals in initiatives developed by…
Drivers of change for lakewater clarity
Lawrence A. Baker; Johanna E. Schussler; Stephanie A. Snyder
2008-01-01
Lakes in the Upper Midwest have undergone extensive lakeshore development over the past 30 years, raising concerns about eutrophication. We examined 11 case study lakes in Minnesota that had undergone substantial shoreline development over the past 30 years to evaluate drivers of change in clarity. Relationships between current Secchi disk transparency (SDT) and the...
Investigating Students' Perceptions of Graduate Learning Outcomes in Mathematics
ERIC Educational Resources Information Center
King, Deborah; Varsavsky, Cristina; Belward, Shaun; Matthews, Kelly
2017-01-01
The purpose of this study is to explore the perceptions mathematics students have of the knowledge and skills they develop throughout their programme of study. It addresses current concerns about the employability of mathematics graduates by contributing much needed insight into how degree programmes are developing broader learning outcomes for…
Effects of altered food intake during pubertal development in male and female Wistar rats
The U.S.EPA is currently validating assays that will be used in a Tier I Screening Battery to detect endocrine disrupting chemicals. A primary concern with the Protocols for the Assessment of Pubertal Development and Thyroid Function in Juvenile Male and Female Rats is that a non...
Huang, David B; Wu, Jashin J; Tyring, Stephen K
2004-10-01
Viral vaccines could be considered among the most important medical achievements of the 20th century. They have prevented much suffering and saved many lives. Although some curative antiviral drugs exist, we desperately depend on efforts by academic, governmental and industrial scientists in the advancement of viral vaccines in the prevention and control of infectious diseases. In the next decade, we hope to see advancement in the development of current and investigational viral vaccines against childhood and adult infections. In this article, we will review the licensed viral vaccines, some of their safety concerns, and the advances in the development of investigational viral vaccines.
Social Competence as a Positive Youth Development Construct: A Conceptual Review
Ma, Hing Keung
2012-01-01
Social competence is defined in terms of interpersonal relationships, self and group identities, and development of citizenship. While the focus of the author's previous research is on relationship and identity, the main focus of this paper is on the development of citizenship. A 4-stage developmental model of citizenship is proposed. A brief discussion of the educational implication of each of the stages is presented. The issues concerning the assessment of social competence are clearly delineated, and the discussion serves as a basis for future studies. Finally, five current issues concerning the launch of the “Moral and National Education (MNE) Subject” in Hong Kong primary and secondary schools are discussed. PMID:22645418
Utter, Jennifer; Denny, Simon; Lucassen, Mathijs; Dyson, Ben
2016-08-10
Learning how to cook is an important skill for developing healthy eating behaviors. Moreover, involvement in home cooking may offer young people opportunities for skill building, identity development and social engagement with their families. Recently, there have been concerns that the current generation of young people may not have the opportunities to develop sufficient cooking skills. These concerns have been addressed by the initiation of numerous, localized interventions. Yet, little is known about where the current generation of young people learn cooking skills. The objective of this study was to describe where the current generation of young people report learning to cook, drawing on nationally representative data from New Zealand. Data were collected as part of Youth2012, a nationally representative survey of secondary school students (n=8500) in New Zealand. Almost all students reported learning to cook and from multiple sources. Almost all students reported learning to cook from a family member (mother, father, or other family member), approximately 60% of students reported that they learned to cook from certain media (cookbooks, TV, or the Internet) and half of all students reported learning to cook at school. There were numerous differences in where students learned to cook by socio-demographic characteristics. Findings from the current research highlight the important role that families play in teaching young people to cook and will be useful for those working with young people to develop these skills.
Gene and Cell Doping: The New Frontier - Beyond Myth or Reality.
Neuberger, Elmo W I; Simon, Perikles
2017-01-01
The advent of gene transfer technologies in clinical studies aroused concerns that these technologies will be misused for performance-enhancing purposes in sports. However, during the last 2 decades, the field of gene therapy has taken a long and winding road with just a few gene therapeutic drugs demonstrating clinical benefits in humans. The current state of gene therapy is that viral vector-mediated gene transfer shows the now long-awaited initial success for safe, and in some cases efficient, gene transfer in clinical trials. Additionally, the use of small interfering RNA promises an efficient therapy through gene silencing, even though a number of safety concerns remain. More recently, the development of the molecular biological CRISPR/Cas9 system opened new possibilities for efficient and highly targeted genome editing. This chapter aims to define and consequently demystify the term "gene doping" and discuss the current reality concerning gene- and cell-based physical enhancement strategies. The technological progress in the field of gene therapy will be illustrated, and the recent clinical progress as well as technological difficulties will be highlighted. Comparing the attractiveness of these technologies with conventional doping practices reveals that current gene therapy technologies remain unattractive for doping purposes and unlikely to outperform conventional doping. However, future technological advances may raise the attractiveness of gene doping, thus making it easier to develop detection strategies. Currently available detection strategies are introduced in this chapter showing that many forms of genetic manipulation can already be detected in principle. © 2017 S. Karger AG, Basel.
Is new always better than old?: The development of human vaccines for anthrax.
Baillie, Leslie W
2009-12-01
Anthrax is caused by a Gram-positive aerobic spore-forming bacillus called Bacillus anthracis. Although primarily a disease of animals, it can also infect man, sometimes with fatal consequences. As a result of concerns over the illicit use of this organism, considerable effort is focused on the development of therapies capable of conferring protection against anthrax. while effective concerns over the toxicity of the current vaccines have driven the development of second-generation products. Recombinant Protective Antigen (rPA), the nontoxic cell-binding component of anthrax lethal toxin, is the principal immunogen of the vaccines currently undergoing human clinical trials. While these new vaccines are likely to show reduced side effects they will still require multiple needle based dosing and the inclusion of the adjuvant alum which will make them expensive to administer and stockpile. To address these issues, researchers are seeking to develop vaccine formulations capable of stimulating rapid protection following needle-free injection which are stable at room temperature to facilitate stockpiling and mass vaccination programs. Recent concerns over the potential use of molecular biology to engineer vaccine resistant strains has prompted investigators to identify additional vaccine targets with which to extend the spectrum of protection conferred by rPA. While the injection of research dollars has seen a dramatic expansion of the anthrax vaccine field it is sobering to remember that work to develop the current second generation vaccines began around the time of the first gulf war. Almost two decades and millions of dollars later we still do not have a replacement vaccine and even when we do some argue that the spectrum of protection that it confers will not be as broad as the vaccine it replaces. If we are to respond effectively to emerging biological threats we need to develop processes that generate protective vaccines in a meaningful time frame and yield products in months not decades!
Kroes, Rob
2017-01-01
This paper's central concern is with signs of fascism in recent political developments in a number of European countries and the United States. It takes the reader back to earlier periods in European and American history when this same anguished question was raised. Thus a longer intellectual history of concerns about the viability of democratic systems is drawn to guide us in our current political evaluations.
Craft, Elena S; Donnelly, Kirby C; Neamtiu, Iulia; McCarty, Kathleen M; Bruce, Erica; Surkova, Irina; Kim, David; Uhnakova, Iveta; Gyorffy, Erika; Tesarova, Eva; Anderson, Beth
2006-12-01
As the next generation of scientists enters the field of environmental health, it is imperative that they view their contributions in the context of global environmental stewardship. In this commentary, a group of international graduate students facilitated by three experienced environmental health scientists present their views on what they consider to be the global environmental health concerns of today. This group convened initially in October 2004 at an international health conference in Prague, Czech Republic. In this report we identify perceived environmental health concerns that exist around the world, with a focus on Central and Eastern Europe. Additionally, we address these perceived problems and offers some potential solutions. At the meeting, students were invited to participate in two panel discussions. One group of young international scientists identified several significant global environmental health concerns, including air pollution, occupational hazards, and risk factors that may exacerbate current environmental health issues. The second panel determined that communication, education, and regulation were the mechanisms for addressing current environmental challenges. In this commentary we expand on the views presented at the meeting and represent the concerns of young investigators from nine different countries. We provide ideas about and support the exchange of information between developed and developing countries on how to handle the environmental health challenges that face the world today.
Locomotive crashworthiness research : volume 1 : model development and validation
DOT National Transportation Integrated Search
1995-07-01
This report is the first of four volumes concerning a study to investigate the costs and benefits of equipping locomotives with various crashworthiness features beyond those currently specified by the Association of American Railroads S-580 specifica...
In-service inspection methods for graphite-epoxy structures on commercial transport aircraft
NASA Technical Reports Server (NTRS)
Phelps, M. L.
1981-01-01
In-service inspection methods for graphite-epoxy composite structures on commercial transport aircraft are determined. Graphite/epoxy structures, service incurred defects, current inspection practices and concerns of the airline and manufacturers, and other related information were determind by survey. Based on this information, applicable inspection nondestructive inspection methods are evaluated and inspection techniques determined. Technology is developed primarily in eddy current inspection.
Ethical issues in perinatal mental health research.
Brandon, Anna R; Shivakumar, Geetha; Lee, Simon Craddock; Inrig, Stephen J; Sadler, John Z
2009-11-01
To review the background of current ethical standards for the conduct of perinatal mental health research and describe the ethical challenges in this research domain. Current literature reflects a growing sentiment in the scientific community that having no information regarding the impact of psychiatric treatment on the mother and developing fetus/infant poses dangers that may exceed the risks involved in research. However, without sufficient consensus across the scientific community, both regulatory bodies and perinatal researchers find themselves without a framework for decision making that satisfactorily limits the risks and facilitates the benefits of participation of pregnant and lactating women in clinical research. Psychiatric research in perinatal mental health is critically important as it enables clinicians and patients to participate in informed decision-making concerning treatment for psychiatric disorders. Specific areas of concern include fetal safety, maternal risk, the therapeutic misconception, commercial interests, forensic/legal issues, the informed consent process, and study design. Developing guidelines that address ethical challenges and include the views and concerns of multiple stakeholders could improve the access of perinatal women to the benefits of participation in mental health research in addition to providing evidence-based mental healthcare for this subpopulation.
Blumberg, Stephen J; Zablotsky, Benjamin; Avila, Rosa M; Colpe, Lisa J; Pringle, Beverly A; Kogan, Michael D
2016-10-01
Autism spectrum disorder diagnoses sometimes change due to misdiagnosis, maturation, or treatment. This study uses a probability-based national survey-the Survey of Pathways to Diagnosis and Services-to compare currently diagnosed (n = 1420) and previously diagnosed (n = 187) children aged 6-17 years based on retrospective parental reports of early concerns about their children's development, responses to those concerns by doctors and other healthcare providers, the type of provider who made the first autism spectrum disorder diagnosis, and the autism spectrum disorder subtype diagnoses received (if any). Propensity score matching was used to control for differences between the groups on children's current level of functioning and other current characteristics that may have been related to diagnosis loss. Approximately 13% of the children ever diagnosed with autism spectrum disorder were estimated to have lost the diagnosis, and parents of 74% of them believed it was changed due to new information. Previously diagnosed children were less likely to have parents with early concerns about verbal skills, nonverbal communication, learning, and unusual gestures or movements. They were also less likely to have been referred to and diagnosed by a specialist. Previously diagnosed children were less likely to have ever received a diagnosis of Asperger's disorder or autistic disorder. © The Author(s) 2015.
Blumberg, Stephen J; Zablotsky, Benjamin; Avila, Rosa M; Colpe, Lisa J; Pringle, Beverly A; Kogan, Michael D
2016-01-01
Autism spectrum disorder (ASD) diagnoses sometimes change due to misdiagnosis, maturation, or treatment. This study uses a probability-based national survey—the Survey of Pathways to Diagnosis and Services—to compare currently diagnosed (n=1420) and previously diagnosed (n=187) children aged 6–17 years based on retrospective parental reports of early concerns about their children’s development, responses to those concerns by doctors and other health care providers, the type of provider who made the first ASD diagnosis, and the ASD subtype diagnoses received (if any). Propensity score matching was used to control for differences between the groups on children’s current level of functioning and other current characteristics that may have been related to diagnosis loss. Approximately 13% of the children ever diagnosed with ASD were estimated to have lost the diagnosis, and parents of 74% of them believe it was changed due to new information. Previously diagnosed children were less likely to have parents with early concerns about verbal skills, nonverbal communication, learning, and unusual gestures or movements. They were also less likely to have been referred to and diagnosed by a specialist. Previously diagnosed children were less likely to have ever received a diagnosis of Asperger’s disorder or autistic disorder. PMID:26489772
Assessment of Peruvian biofuel resources and alternatives
DOE Office of Scientific and Technical Information (OSTI.GOV)
Harper, J.P.; Smith, W.; Mariani, E.
1979-08-01
Comprehensive assessment of the biofuel potential of Peru is based on: determination of current biofuel utilization practices, evauation of Peruvian biomass productivity, identification of Peruvian agricultural and forestry resources, assessment of resource development and management concerns, identification of market considerations, description of biofuel technological options, and identification of regional biofuel technology applications. Discussion of current biofuel utilization centers on a qualitative description of the main conversion approaches currently being practiced in Peru. Biomass productivity evaluations consider the terrain and soil, and climatic conditions found in Peru. The potential energy from Peruvian agricultural and forestry resources is described quantitatively. Potental regionalmore » production of agricultural residues and forest resources that could supply energy are identified. Assessment of resource development and management concerns focuses on harvesting, reforestation, training, and environmental consequences of utilization of forest resources. Market factors assessed include: importation, internal market development, external market development, energy policy and pricing, and transportation. Nine biofuel technology options for Peru are identified: (1) small-to-medium-scale gasification, (2) a wood waste inventory, (3) stationary and mobile charcoal production systems, (4) wood distillation, (5) forest resource development and management, (6) electrical cogeneration, (7) anaerobic digestion technology, (8) development of ethanol production capabilities, and (9) agricultural strategies for fuel production. Applications of these biofuel options are identified for each of the three major regions - nine applications for the Costa Region, eight for the Sierra Region, and ten for the Selva Region.« less
Lemos, Rayla Amaral; Veríssimo, Maria de La Ó Ramallo
2015-12-01
Understanding the conceptions of premature children caregivers on child development and associated factors. An exploratory-descriptive qualitative study of 12 families with children under three years of age. Interviews were submitted to thematic content analysis, systematized into the categories of Bioecological Theory of Human Development: Process, Person, Context and Time, and in the Functional Development category. There are concerns about impairment in the current and future development of a Person/child defined as fragile as a result of premature birth (Time dimension), minimized by the scope of observable competencies such as motor skills. The Context, especially family and health services, and Proximal Processes, described as one-way caregiver interactions, are considered determinants of development. Functional Development is considered a natural consequence and result of education. The support network is crucial, supporting or limiting care. Concerns about the development mobilize caregivers to stimulate the premature child/person and requests family and healthcare assistance.
Comparison of thruster configurations in attitude control systems. M.S. Thesis. Progress Report
NASA Technical Reports Server (NTRS)
Boland, J. S., III; Drinkard, D. M., Jr.; White, L. R.; Chakravarthi, K. R.
1973-01-01
Several aspects concerning reaction control jet systems as used to govern the attitude of a spacecraft were considered. A thruster configuration currently in use was compared to several new configurations developed in this study. The method of determining the error signals which control the firing of the thrusters was also investigated. The current error determination procedure is explained and a new method is presented. Both of these procedures are applied to each of the thruster configurations which are developed and comparisons of the two methods are made.
Meeting the Challenge: Quality Systems in Private Higher Education in Kuwait
ERIC Educational Resources Information Center
Al-Atiqi, Imad M.; Alharbi, Lafi M.
2009-01-01
In Kuwait, as in other rapidly-developing higher education systems, one major area of concern is ensuring the quality of education offered by private providers. This paper briefly reviews the history of the development of higher education in Kuwait since its inception in 1936. It considers various quality systems currently in place in other…
The Potential of School-Linked Centers To Promote Adolescent Health and Development. Working Paper.
ERIC Educational Resources Information Center
Millstein, Susan G.
The future of school-linked adolescent health centers cannot be determined without further evaluation. The recent development of school-linked health centers stems from concerns about the special health needs of adolescents. Currently there are 125 school-based and school-linked centers in operation. Characteristics include the following: (1) most…
Social Media and Marketing Education: A Review of Current Practices in Curriculum Development
ERIC Educational Resources Information Center
Brocato, E. Deanne; White, Nathan James; Bartkus, Kenneth; Brocato, Ashley Ann
2015-01-01
Given the presumed importance of social media to marketing, along with the apparent lack of research concerning social media curriculum development, the purpose of this study is to conduct a systematic analysis of social media curriculum through the evaluation of undergraduate course syllabi in the United States. This research is intended to…
Teaching Energy as Part of Education for Sustainability
ERIC Educational Resources Information Center
Tas, Maarten; McKeon, Frankie; Charnley, Fiona; Fleming, Margaret
2014-01-01
This article describes how energy issues and education for sustainable development (ESD) are part of the agenda for two current European projects, CoDeS and SUSTAIN. The latter is mainly concerned with the development of inquiry-based primary and lower secondary science education while the former is a network that aims to learn more about…
Child Labour and Educational Success in Portugal
ERIC Educational Resources Information Center
Goulart, Pedro; Bedi, Arjun S.
2008-01-01
The current debate on child labour focuses on developing countries. However, Portugal is an example of a relatively developed country where child labour is still a matter of concern as between 8% and 12% of Portuguese children may be classified as workers. This paper studies the patterns of child labour in Portugal and assesses the consequences of…
ERIC Educational Resources Information Center
Makel, Matthew C.; Wai, Jonathan; Putallaz, Martha; Malone, Patrick S.
2015-01-01
Despite growing concern about the need to develop talent across the globe, relatively little empirical research has examined how students develop their academic talents. Toward this end, the current study explored how academically talented students from the United States and India spend their time both in and out of school. Indian students…
Cotton Production in Mali: Subsidies or Sustainable Development?
ERIC Educational Resources Information Center
Moore, Lindsey
2007-01-01
Current trade rules concerning cotton subsidies are intricately linked with poverty and hunger in Mali. Over half of Mali's economy and over 30 million people depend directly on cotton. It is the main cash crop and the most important source of export revenue. Cotton also plays a key role in development policies and in the fight against poverty by…
Developing an urban forest carbon market
M. Armstrong; J. Siry; Michael Bowker
2009-01-01
Countries, states, localities, businesses, and individuals are taking action to mitigate greenhouse gas levels and production as a response to concerns over climate change. Europe currently has mandatory greenhouse gas emission legislation and a large developed emission trading market, as opposed to the U.S. where voluntary markets to reduce green house gas emissions...
Lifelong Teacher Education and the Community School. UIE Monographs 10.
ERIC Educational Resources Information Center
Dove, Linda A.
This monograph synthesizes and summarizes current ideas and actions concerning teacher-community linkages. Its main emphasis is on developing countries, where primary and lower secondary schools are major policy tools in the drive for national and economic development and where most people live and will continue to live in rural areas. Based on an…
Predicting user concerns about online privacy in Hong Kong.
Yao, Mike Z; Zhang, Jinguang
2008-12-01
Empirical studies on people's online privacy concerns have largely been conducted in the West. The global threat of privacy violations on the Internet calls for similar studies to be done in non-Western regions. To fill this void, the current study develops a path model to investigate the influence of people's Internet use-related factors, their beliefs in the right to privacy, and psychological need for privacy on Hong Kong people's concerns about online privacy. Survey responses from 332 university students were analyzed. Results from this study show that people's belief in the right to privacy was the most important predictor of their online privacy concerns. It also significantly mediated the relationship between people's psychological need for privacy and their concerns with privacy violations online. Moreover, while frequent use of the Internet may increase concerns about online privacy issues, Internet use diversity may actually reduce such worries. The final model, well supported by the observed data, successfully explained 25% of the variability in user concerns about online privacy.
2009-07-01
ship with five large switchboards. Two motor drives control two permanent magnet motors (PMM), which are currently in development, powering hybrid...an 80 percent MCR and a full hotel load. The next important decision that was made concerned the motor. Induction motors and permanent magnet motors were
DOT National Transportation Integrated Search
1984-01-01
This report reviews the literature concerning written driver license examinations. The research literature shows that current written examinations are poor predictors of unsafe drivers. Although some studies demonstrate significant relationships betw...
Controlled Nuclear Fusion: Status and Outlook
ERIC Educational Resources Information Center
Rose, David J.
1971-01-01
Presents the history, current concerns and potential developments of nuclear fusion as a major energy source. Controlled fusion research is summarized, technological feasibility is discussed and environmental factors are examined. Relationships of alternative energy sources as well as energy utilization are considered. (JM)
ERIC Educational Resources Information Center
Wentling, Rose Mary; Palma-Rivas, Nilda
1998-01-01
In-depth interviews with 12 diversity experts identified organizational and individual barriers inhibiting development of a diverse workforce. Primary reasons for diversity initiatives included improving productivity, enhancing social responsibility, and addressing legal concerns. (SK)
Effects of perfluorinated chemicals on adipocyte development
Obesity is a growing concern in the US population. Current interest is high in the role played by environmental factors called obesogens that may contribute to obesity through developmental exposure. One class of potential obesogens is the family of perfluorinated chemicals used ...
Deleterious Effects From Occupational Exposure to Ethylene Thiourea in Pregnant Women.
Mutic, Abby D; Baker, Brenda J; McCauley, Linda A
2017-12-01
Human exposure to endocrine disrupting chemicals (EDCs) has become common as a result of widespread application of these chemicals to the food supply, environmental contamination, and occupational exposures (Caserta et al., 2011). However, relatively little is known about the effects of EDCs such as ethylene thiourea (ETU) in developing fetuses and the lasting implications of this disruption on human development from birth through adulthood. Of highest concern are chronic, low-dose exposures among industrial and agricultural workers. Current knowledge regarding the significance of endocrine thyroid signaling on normal human development raises serious concerns about the possible deleterious effects of EDCs in the developing fetus, children, and mature adults. Occupational health nurses are critical in identifying women and families at increased risk of ETU exposure and mitigating early exposures in pregnancy.
Comprehensive Nuclear-Test-Ban Treaty: Background and Current Developments
2008-09-18
needed to conduct a nuclear test. Critics raised concerns about the implications of these policies for testing and new weapons. At present, Congress...as it is reduced, is reliable and safe. So he has not ruled out testing in the future, but there are no plans to do so.’”4 Critics expressed concern...ten-year-old moratorium on nuclear weapons testing.”5 Another critic felt that increased funding for test readiness would in effect give prior
Radioactive and mixed waste - risk as a basis for waste classification. Symposium proceedings No. 2
DOE Office of Scientific and Technical Information (OSTI.GOV)
NONE
The management of risks from radioactive and chemical materials has been a major environmental concern in the United states for the past two or three decades. Risk management of these materials encompasses the remediation of past disposal practices as well as development of appropriate strategies and controls for current and future operations. This symposium is concerned primarily with low-level radioactive wastes and mixed wastes. Individual reports were processed separately for the Department of Energy databases.
ERIC Educational Resources Information Center
Relyea, Harold C.; Halchin, L. Elaine; Hogue, Henry B.; Agnew, Grace; Martin, Mairead; Schottlaender, Brian E. C.; Jackson, Mary E.
2003-01-01
Theses five reports address five special issues: the effects of the September 11 attacks on information management, including homeland security, Web site information removal, scientific and technical information, and privacy concerns; federal policy for electronic government information; digital rights management and libraries; library Web portal…
Anesthesia and the developing brain.
Aker, John; Block, Robert I; Biddle, Chuck
2015-04-01
Despite the profound evolution in the safety and efficacy of neonatal and pediatric anesthesia, questions remain concerning the long-term neurotoxic and neurocognitive effects of the drugs used in anesthetic care. A variety of prospective animal models and retrospective human studies exist that inconsistently demonstrate a detrimental effect of early life exposure to anesthetic drugs and subsequent learning performance. Limitations associated with both non-human and human observational studies are critiqued. Research currently underway is briefly described. A framework for discussing the relevant issues with concerned parents is presented.
High accuracy switched-current circuits using an improved dynamic mirror
NASA Technical Reports Server (NTRS)
Zweigle, G.; Fiez, T.
1991-01-01
The switched-current technique, a recently developed circuit approach to analog signal processing, has emerged as an alternative/compliment to the well established switched-capacitor circuit technique. High speed switched-current circuits offer potential cost and power savings over slower switched-capacitor circuits. Accuracy improvements are a primary concern at this stage in the development of the switched-current technique. Use of the dynamic current mirror has produced circuits that are insensitive to transistor matching errors. The dynamic current mirror has been limited by other sources of error including clock-feedthrough and voltage transient errors. In this paper we present an improved switched-current building block using the dynamic current mirror. Utilizing current feedback the errors due to current imbalance in the dynamic current mirror are reduced. Simulations indicate that this feedback can reduce total harmonic distortion by as much as 9 dB. Additionally, we have developed a clock-feedthrough reduction scheme for which simulations reveal a potential 10 dB total harmonic distortion improvement. The clock-feedthrough reduction scheme also significantly reduces offset errors and allows for cancellation with a constant current source. Experimental results confirm the simulated improvements.
Direct Lending: How To Improve Implementation.
ERIC Educational Resources Information Center
Jepsen, Keith
This evaluation study developed 29 recommendations concerning the implementation of direct loans in providing financial assistance to postsecondary school students. The investigation included examination of a current Department of Education (ED) pilot program, a video teleconference to discuss direct lending with 23 individuals in education…
NEXT GENERATION SEDIMENT TOXICITY TESTING VIA DNA MICROARRAYS - PHASE I
The current SBIR solicitation states that the EPA is seeking “better sampling, analysis, and monitoring technologies” to improve hazardous waste management. Development of new methods for testing contaminated sediments is an area of particular concern because many industri...
10 CFR 784.4 - Advance waiver.
Code of Federal Regulations, 2012 CFR
2012-01-01
... the contract objectives are concerned with the public health, public safety, or public welfare; (k... public, the Secretary or designee (currently the Assistant General Counsel for Technology Transfer and... utilization of the research, development, and demonstration results; (e) The extent to which the Government...
10 CFR 784.4 - Advance waiver.
Code of Federal Regulations, 2011 CFR
2011-01-01
... the contract objectives are concerned with the public health, public safety, or public welfare; (k... public, the Secretary or designee (currently the Assistant General Counsel for Technology Transfer and... utilization of the research, development, and demonstration results; (e) The extent to which the Government...
10 CFR 784.4 - Advance waiver.
Code of Federal Regulations, 2014 CFR
2014-01-01
... the contract objectives are concerned with the public health, public safety, or public welfare; (k... public, the Secretary or designee (currently the Assistant General Counsel for Technology Transfer and... utilization of the research, development, and demonstration results; (e) The extent to which the Government...
Cardiovascular (CV) safety concerns are a significant source of drug development attrition in the pharmaceutical industry today. Though current nonclinical testing paradigms have largely prevented catastrophic CV events in Phase I studies, many challenges relating to the inabil...
Integration of DNA barcoding approaches into aquatic bioassessments
The Clean Water Act directs states to protect water resources by developing criteria based in part on biological assessments of natural aquatic ecosystems. Current protocols can be limited by the availability of taxonomic expertise and concerns about precision and accuracy in mor...
Expert and Knowledge Based Systems.
ERIC Educational Resources Information Center
Demaid, Adrian; Edwards, Lyndon
1987-01-01
Discusses the nature and current state of knowledge-based systems and expert systems. Describes an expert system from the viewpoints of a computer programmer and an applications expert. Addresses concerns related to materials selection and forecasts future developments in the teaching of materials engineering. (ML)
DOT National Transportation Integrated Search
2010-01-01
The current project, funded by MIOH-UTC for the period 1/1/2009- 4/30/2010, is concerned : with the development of the framework for a transportation facility inspection system using : advanced image processing techniques. The focus of this study is ...
ERIC Educational Resources Information Center
Wickwire, Pat Nellor, Ed.
2001-01-01
This journal of the California Association for Counseling and Development attempts to identify the current issues of concern in the counseling field and share research to help improve the professional learning community. The articles in this issue include: "The Editor's Message" (Pat Nellor Wickwire); "The CACD President's…
Explaining Family Interactions.
ERIC Educational Resources Information Center
Fitzpatrick, Mary Anne, Ed.; Vangelisti, Anita L., Ed.
A detailed review of current research and state-of-the-art ideas concerning both communication processes and family functioning is presented in this collection of articles. The volume is organized around three sections. Part 1, "The Development of Family Communication Patterns," contains: (1) "Communication in Infancy"…
Developing cost effective plans for low volume bridges
DOT National Transportation Integrated Search
2006-09-01
There is currently an escalating concern across the state of Kansas with respect to the age : and condition of low volume bridges and methods available to modify or replace them. A : high percentage of low volume bridges in the state of Kansas requir...
ERIC Educational Resources Information Center
Wickwire, Pat Nellor, Ed.
2000-01-01
This journal of the California Association for Counseling and Development attempts to identify the current issues of concern in the counseling field and share research to help improve the professional learning community. The articles in this issue include: "The Editor's Message" (Pat Nellor Wickwire); "The CACD President's…
Adaptation Research in Rehabilitation Counseling
ERIC Educational Resources Information Center
Parker, Randall M.
2007-01-01
This paper reviews current research concerning psychosocial adaptation to chronic illness and disability and presents recommendations for future development of theories in this area. First, those who craft or adapt theories must use nondisabling, respectful, and empowering language. Rehabilitation professionals must avoid terms that connote…
Uses and Doses of Local Anesthetics in Fish, Amphibians, and Reptiles.
Chatigny, Frederic; Kamunde, Collins; Creighton, Catherine M; Stevens, E Don
2017-05-01
Local anesthetics are an integral part of routine pain management in mammals, yet their use is relatively limited in fish, amphibians and reptiles. These animals frequently undergo potentially painful surgical procedures and therefore could possibly benefit from those drugs. Some recommendations are currently available in the literature concerning analgesic use in these animals. However the pharmacological properties, safety and often efficacy of local anesthetic drugs have not been investigated yet in fish, amphibians, or reptiles. This review compiled current information concerning the use of those agents in fish, reptiles and amphibians to help clinicians make an informed decision as to which dose and drug to use. The resulting literature search showed that the literature concerning use of local analgesics in fish and amphibians is very limited while the literature for reptiles is more extensive. We found few experimental studies evaluating the efficacy of local anesthetics. Further studies would provide additional information for developing guidelines to improve the welfare of fish, amphibians and reptiles.
Uses and Doses of Local Anesthetics in Fish, Amphibians, and Reptiles
Chatigny, Frederic; Kamunde, Collins; Creighton, Catherine M; Stevens, E Don
2017-01-01
Local anesthetics are an integral part of routine pain management in mammals, yet their use is relatively limited in fish, amphibians and reptiles. These animals frequently undergo potentially painful surgical procedures and therefore could possibly benefit from those drugs. Some recommendations are currently available in the literature concerning analgesic use in these animals. However the pharmacological properties, safety and often efficacy of local anesthetic drugs have not been investigated yet in fish, amphibians, or reptiles. This review compiled current information concerning the use of those agents in fish, reptiles and amphibians to help clinicians make an informed decision as to which dose and drug to use. The resulting literature search showed that the literature concerning use of local analgesics in fish and amphibians is very limited while the literature for reptiles is more extensive. We found few experimental studies evaluating the efficacy of local anesthetics. Further studies would provide additional information for developing guidelines to improve the welfare of fish, amphibians and reptiles. PMID:28535859
NASA Technical Reports Server (NTRS)
Elrad, Tzilla (Editor); Filman, Robert E. (Editor); Bader, Atef (Editor)
2001-01-01
Computer science has experienced an evolution in programming languages and systems from the crude assembly and machine codes of the earliest computers through concepts such as formula translation, procedural programming, structured programming, functional programming, logic programming, and programming with abstract data types. Each of these steps in programming technology has advanced our ability to achieve clear separation of concerns at the source code level. Currently, the dominant programming paradigm is object-oriented programming - the idea that one builds a software system by decomposing a problem into objects and then writing the code of those objects. Such objects abstract together behavior and data into a single conceptual and physical entity. Object-orientation is reflected in the entire spectrum of current software development methodologies and tools - we have OO methodologies, analysis and design tools, and OO programming languages. Writing complex applications such as graphical user interfaces, operating systems, and distributed applications while maintaining comprehensible source code has been made possible with OOP. Success at developing simpler systems leads to aspirations for greater complexity. Object orientation is a clever idea, but has certain limitations. We are now seeing that many requirements do not decompose neatly into behavior centered on a single locus. Object technology has difficulty localizing concerns invoking global constraints and pandemic behaviors, appropriately segregating concerns, and applying domain-specific knowledge. Post-object programming (POP) mechanisms that look to increase the expressiveness of the OO paradigm are a fertile arena for current research. Examples of POP technologies include domain-specific languages, generative programming, generic programming, constraint languages, reflection and metaprogramming, feature-oriented development, views/viewpoints, and asynchronous message brokering. (Czarneclu and Eisenecker s book includes a good survey of many of these technologies).
Sire: An Automated Software Development Environment.
1983-12-01
understanding the fundamental nature of the software process" (Osterweil, 1981: 35). In fact, the optimal environment for most applications is found by extending... resource planning and other management concerns that cause these problems. Therefore, a complete ASDE should attempt to provide the -21...management with some type of control over the project without impeding the actual development process. Facilities that estimate current resource
ERIC Educational Resources Information Center
Snell, Julia; Andrews, Richard
2017-01-01
The issue of whether a regional accent and/or dialect impact(s) on the development of literacy skills remains current in the UK. For decades the issue has dogged debate concerning education outcomes, portable skills and employability. This article summarises research on the topic using systematic review methodology. A scoping review was undertaken…
ERIC Educational Resources Information Center
Openshaw, Roger
2007-01-01
Throughout Australasia, indigenous educational issues remain a subject of considerable debate. In New Zealand, Maori underachievement in education has long been a matter of widespread concern. Currently the most highly visible professional development programme now operating in New Zealand mainstream secondary schools, Te Kotahitanga claims to…
ERIC Educational Resources Information Center
Quinn, Diana
2010-01-01
Purpose: The purpose of this paper is to examine current approaches to teaching used in academic development services and consider the diversity of their learners (academic faculty). Faculty engagement with teaching issues and innovations remains a concern for the higher education sector. The academic population contains large numbers of…
ERIC Educational Resources Information Center
Hathorn, Conley; Dillon, Anna Marie
2018-01-01
This paper is concerned with exploring the microsystem of teachers' experiences with education reform within the action research (AR) model for professional development (PD). Within the macrosystem of current major education reform in the UAE, it is timely to explore teachers' experiences of AR as PD to improve pedagogy. The process of engaging in…
ERIC Educational Resources Information Center
Jessup, Michael Hyle
This study is concerned with the historical development of certain areas of university extension--credit and noncredit courses, correspondence study, and conferences, institutes, and short courses--which appear widespread and important in current extension programs. Credit and noncredit courses and correspondence study were among the earliest…
African Americans and Self-Help Education: The Missing Link in Adult Education. ERIC Digest No. 222.
ERIC Educational Resources Information Center
Rowland, Michael L.
Self-help education and self-help literature is important in the lives of African American adults, but the basic models of learning, development, and program planning in adult education have often been developed with little concern for the unique needs of African Americans. In addition, current theories of adult learning often lack understanding…
Bud removal affects shoot, root, and callus development of hardwood Populus cuttings
A.H. Wiese; J.A. Zalesny; D.M. Donner; Ronald S., Jr. Zalesny
2006-01-01
The inadvertent removal and/or damage of buds during processing and planting of hardwood poplar (Populus spp.) cuttings are a concern because of their potential impact on shoot and root development during establishment. The objective of the current study was to test for differences in shoot dry mass, root dry mass, number of roots, length of the...
ERIC Educational Resources Information Center
Pardhan, Almina
2011-01-01
In the current global push to explore the diverse and complex ways in which the school culture contributes to the shaping of young children's gender identity, early childhood teachers' role in this process is an area of concern which has received limited attention. Furthermore, the schooling experiences of early years children in developing world…
ERIC Educational Resources Information Center
Kidder, Sherri L.
The general development of the concept of self-esteem is reviewed, and concerns about the research strategies and issues are discussed. This paper focuses on adolescent self-esteem. Research is presented on global self-esteem, domain specific self-esteem as it relates to global self-esteem, and the identification of self-esteem trajectories.…
WORK SITE CLINICAL AND NEUROBEHAVIORAL ASSESSMENT OF SOLVENT EXPOSED MICROELECTRONICS WORKERS
A group of 25 workers currently (5), or formerly (20), involved in the manufacture of hybrid microcircuits underwent clinical evaluations at the request of a management-union committee concerned about chronic solvent exposures in a research and development laboratory. attery of n...
Developing cost effective plans for low volume bridges
DOT National Transportation Integrated Search
2006-09-01
There is currently an escalating concern across the state of Kansas with respect to the age and condition of low volume bridges and methods available to modify or replace them. A high percentage of low volume bridges in the state of Kansas require or...
Antibody Protection Against Botulinum Neurotoxin Intoxication In Mice
USDA-ARS?s Scientific Manuscript database
Adulteration of food or feed with any of the seven serotypes of botulinum neurotoxin (BoNT) is a potential bioterrorism concern. Currently, there is strong interest in the development of detection reagents, vaccines, therapeutics and other countermeasures. A sensitive immunoassay for detecting BoNT/...
Head Start Combats Baby Bottle Tooth Decay Among Native American Families.
ERIC Educational Resources Information Center
Phillips, Margaret G.; Stubbs, Phyllis E.
1987-01-01
Presents current developments concerning nursing bottle caries--"baby bottle tooth decay"--and spotlights a program funded by Head Start to reduce the prevalence of these painful and disfiguring, but preventable, children's dental diseases among American Indians and Alaska Native families. (Author/BB)
ERIC Educational Resources Information Center
Trustee Quarterly, 1991
1991-01-01
These four issues of "Trustee Quarterly" focus on topics of current concern to community college trustees. The winter 1991 issue contains articles examining the trustee role in helping diverse students achieve, a reconceptualization of community college finance, the development of a statewide communications plan by the Washington trustees, an…
Chapekar, M S
1996-01-01
Several biologic-biomaterial combinations are currently under development in an attempt to modulate tissue or organ function in patients. The FDA regulations on combination products and the intercenter agreements among the Center for Biologics Evaluation and Research (CBER), the Center for Devices and Radiological Health (CDRH), and the Center for Drugs Evaluation and Research (CDER) provide further guidance on center jurisdiction of combination products and other products where there are jurisdictional concerns. The biological component of biologic-biomaterial combinations raises a number of issues that relate to the safety and bioactivity of the final product. For example, transmission of adventitious agents to patients via somatic cells, tissue, or cell-derived products is a major safety concern as are in vivo inflammatory responses elicited by the biomaterial component. CBER has drafted a number of "Points to Consider" documents to provide further guidance in the development of biological products. The intent of this article is to provide the highlights of the FDA regulations for combination products and the intercenter agreement between CBER and CDRH delineating the responsibilities of each center for medical device activities. In addition, the article focuses on the CBER's concerns related to the development of somatic cell-biomaterial combinations for therapeutic use.
The concerns and interests of expectant and new parents: assessing learning needs.
Svensson, Jane; Barclay, Lesley; Cooke, Margaret
2006-01-01
Antenatal education is an important component of antenatal care in the developed world, but research indicates that it may not be meeting consumer needs. This article provides an overview of a needs assessment that aimed to determine the concerns and interests of expectant and new parents and how they prefer to learn during the periods of pregnancy and the early weeks of parenthood. The findings could be used to develop an innovative approach to antenatal education in order to prepare expectant and new parents for the birth experience and the early weeks of parenthood. The current study's results identified that expectant and new parents' concerns and interests during pregnancy, childbirth, and new parenting fall within five interrelated conceptual areas: 1) perceiving achievement or failure; 2) taking on "risk"; 3) riding an emotional "roller coaster" of joy, anxiety, and uncertainty; 4) needing to "know...what is normal"; and 5) needing help to "perform well."
Ebola vaccine development plan: ethics, concerns and proposed measures.
Folayan, Morenike Oluwatoyin; Yakubu, Aminu; Haire, Bridget; Peterson, Kristin
2016-02-08
The global interest in developing therapies for Ebola infection management and its prevention is laudable. However the plan to conduct an emergency immunization program specifically for healthcare workers using experimental vaccines raises some ethical concerns. This paper shares perspectives on these concerns and suggests how some of them may best be addressed. The recruitment of healthcare workers for Ebola vaccine research has challenges. It could result in coercion of initially dissenting healthcare workers to assist in the management of EVD infected persons due to mistaken beliefs that the vaccine offers protection. It could also affect equity and justice. For example, where people who are not skilled health care professionals but who provide care to patients infected with Ebola (such as in home care settings) are not prioritized for vaccination. The possibility of study participants contracting Ebola infection despite the use of experimental vaccine, and the standard of care they would receive, needs to be addressed clearly, transparently and formalized as part of the ethics review process. Future access to study products in view of current status of the TRIPS agreement needs to be addressed. Finally, broad stakeholder engagement at local, regional and international levels needs to be promoted using available communication channels to engage local, regional and international support. These same concerns are applicable for current and future epidemics. Successful Ebola vaccine development research requires concerted efforts at public dialogue to address misconceptions, equity and justice in participant selection, and honest discussions about risks, benefits and future access. Public dialogue about Ebola vaccine research plans is crucial and should be conducted by trusted locals and negotiated between communities, researchers and ethics committees in research study sites.
Fraser, Ashley M; Padilla-Walker, Laura M; Coyne, Sarah M; Nelson, Larry J; Stockdale, Laura A
2012-05-01
Exposure to media violence, including violent video gaming, can have a cognitive desensitization effect, lowering empathic concern for others in need. Since emerging adulthood offers increased opportunities to volunteer, strengthen relationships, and initiate new relationships, decreases in empathic concern and prosocial behavior may prove inhibitive to optimal development during this time. For these reasons, the current study investigated associations between violent video gaming, empathic responding, and prosocial behavior enacted toward strangers, friends, and family members. Participants consisted of 780 emerging adults (M age = 19.60, SD = 1.86, range = 18–29, 69% female, 69% Caucasian) from four universities in the United States. Results showed small to moderate effects between playing violent video gaming and lowered empathic concern for both males and females. In addition, lowered empathic concern partially mediated the pathways between violent video gaming and prosocial behavior toward all three targets (at the level of a trend for females), but was most strongly associated with lower prosocial behavior toward strangers. Discussion highlights how violent video gaming is associated with lower levels of prosocial behavior through the mechanism of decreased empathic concern, how this association can affect prosocial behavior differently across target, and finally what implications this might have for development during emerging adulthood.
1987-05-01
possibilities and the latter providing a photodetector with low dark currents . Some mention will also be made of structures devised by Nakagawa7 ,8...developments concerning the growth and the characterization of Hgl_xCdxTe-Cdte SLs and related Hg based superlattice systems. These SLs are now currently ...minority carriers in the base region. When a current is flowing, the drift velocities of minority and majority carriers are oppositely directed, and
Breaking up is hard to do: lessons learned from a pharma-free practice transformation.
Evans, David; Hartung, Daniel M; Beasley, Denise; Fagnan, Lyle J
2013-01-01
Academic medical centers are examining relationships with the pharmaceutical industry and making changes to limit interactions. Most doctors, however, practice outside of academic institutions and see pharmaceutical detailers and accept drug samples and gifts. Little guidance for practicing physicians exists about transforming practices to become pharma-free. Consideration must be given to the impact on practice culture, staff views, and patient needs. A small private practice, setting out to transform into a pharma-free clinic, used a practice transformation process that examined the industry presence in the clinic, educated the doctors on potential conflicts of interest, and improved practice flow. Staff were given the opportunity to share concerns, and their issues were acknowledged. Educational interventions were developed to help providers keep current. Finally, efforts were made to educate patients about the policy. The clinic recorded the degree to which it was detailed. Loss of gifts, keeping current with new drugs, and managing without samples were noted concerns. Policy change champions developed strategies to address concerns. A shift in practice culture to a pharma-free clinic is achievable and maintainable over time. Barriers to success can be identified and overcome with attention given to careful gathering of information, staff input, and stakeholder education.
[Obesity in children. Current concerns].
Casado de Frías, Enrique
2006-01-01
In the last years there has been a growing interest in chilhood obesity in all developed countries. There is a great concern that is prevalence has raised 2-3 fold during the last 20 years. In the spanish chilhood population the obesity prevalence is estimated around 13%. Of note also, a number of other pathologies develop concomitantly with obesity during chilhood. These include type 2 diabetes, a range of respiratory problems, a metabolic syndrome, liver steatosis and seudotumor cerebri among others. Taking for granted that chilhood obesity in its roots is an exogenous disorder, preventive interventions should focus on modifying those ethiologies, improving the ways and nature of chilhood nutrition and its social and ludic behaviours.
Shoulder arthroplasty options in young (<50 years old) patients: review of current concepts.
Johnson, Michael H; Paxton, E Scott; Green, Andrew
2015-02-01
Prosthetic shoulder arthroplasty provides excellent pain relief and functional restoration for patients with glenohumeral arthritis, but concerns of survivorship have limited its use in younger patients. Despite general reports of high long-term survivorship, implant failure and functional deterioration after total shoulder arthroplasty are major concerns in the management of younger patients. In addition to having a longer life expectancy, younger patients also tend to be more active and can be expected to place greater demands on their shoulder arthroplasty. Alternative strategies have been developed and used for shoulder arthroplasty in younger patients. This manuscript reviews current concepts of shoulder arthroplasty in young patients. Copyright © 2015 Journal of Shoulder and Elbow Surgery Board of Trustees. Published by Elsevier Inc. All rights reserved.
Development and current applications of assisted fertilization.
Palermo, Gianpiero D; Neri, Queenie V; Monahan, Devin; Kocent, Justin; Rosenwaks, Zev
2012-02-01
Since the very early establishment of in vitro insemination, it became clear that one of the limiting steps is the achievement of fertilization. Among the different assisted fertilization methods, intracytoplasmic sperm injection emerged as the ultimate technique to allow fertilization with ejaculated, epididymal, and testicular spermatozoa. This work describes the early steps that brought forth the development of intracytoplasmic sperm injection and its role in assisted reproductive techniques. The current methods to select the preferential male gamete will be elucidated and the concerns related to the offspring of severe male factor couples will be discussed. Copyright © 2012. Published by Elsevier Inc.
Welschehold, Michael; Kraus, Eva
2004-11-01
In this study, the medical directors of all Bavarian district psychiatric hospitals evaluated certain aspects of the integration of their hospitals into the development of regional community psychiatry networks ("Gemeindepsychiatrische Verbunde" - GPVs). They were asked to rate the actual quantity of cooperation between their hospitals and diverse community based services and to express their requests concerning the quality of cooperation. An estimation of possible advantages of the hospitals' integration in GPVs and expectations to future perspectives of GPV development were also investigated. The data were collected by a written questionnaire. The results of the survey indicate that a high relevance is attached to GPV: inspite of current heterogenous developments and inspite of existing skepticism concerning the feasibility of a complete GPV structure, medical directors strongly approve of seeing their hospitals actively engaged in the further development of community psychiatry networks.
Health concerns associated with unconventional gas mining in rural Australia.
Haswell, Melissa R; Bethmont, Anna
2016-01-01
Many governments globally are investigating the benefits and risks associated with unconventional gas mining for shale, tight and coal seam gas (coalbed methane) to determine whether the industry should proceed in their jurisdiction. Most locations likely to be developed are in rural areas, with potential impact on farmers and small communities. Despite significant health concerns, public health knowledge and growing evidence are often overlooked in decision-making. It is difficult to gain a broad but accurate understanding of the health concerns for rural communities because the evidence has grown very recently and rapidly, is complex and largely based in the USA, where the industry is advanced. In 2016, a concerned South Australian beef and lamb farmer in an area targeted for potential unconventional gas development organised visits to homes in developed unconventional gas areas of Pennsylvania and forums with leading researchers and lawyers in Pennsylvania and New York. Guided by priorities identified during this trip, this communication concisely distils the research evidence on these key concerns, highlighting the Australian situation where evidence exists. It summarises key information of particular concern to rural regions, using Australia as an example, to assist rural health professionals to be better prepared to engage in decision-making and address the challenges associated with this new industry. Discussions with communities and experts, supported by the expanding research from the USA and Australia, revealed increasing health concerns in six key areas. These are absence of a safe solution to the toxic wastewater management problems, air pollution, land and water competition, mental health and psychosocial wellbeing risks, fugitive methane emissions and lack of proven regulatory regimes. Emerging epidemiological studies suggesting interference with foetal development and birth outcomes, and exacerbation of asthma conditions, are particularly concerning to rural families and livestock. Rural residents in potentially affected areas should be supported to access and interpret the best current evidence regarding the multiple health concerns associated with unconventional gas mining. This knowledge should be part of wider discourse and decision-making processes driving local economic development and national and global energy choices.
Lam, Pik-Ling; Wong, Wai-Yeung; Bian, Zhaoxiang; Chui, Chung-Hin; Gambari, Roberto
2017-02-01
Nanotechnology manipulates therapeutic agents at the nanoscale for the development of nanomedicines. However, there are current concerns over nanomedicines, mainly related to the possible toxicity of nanomaterials used for health medications. Due to their small size, they can enter the human body more readily than larger sized particles. Green chemistry encompasses the green synthesis of drug-loaded nanoparticles by reducing the use of hazardous materials in the synthesis process, thus reducing the adverse health impacts of pharmaceutics. This would greatly expand their potential in biomedical treatments. This review highlights the potential risks of nanomedicine formulations to health, delivery routes of green nanomedicines, recent advances in the development of green nanoscale systems for biomedical applications and future perspectives for the green development of nanomedicines.
Green, Shari
2013-11-01
Orofacial myologists are frequently called upon to address retained oral habit concerns. During this process, current I.A.O.M. recommended treatment includes addressing tongue, lip, and jaw rest posture concerns. Following digit sucking remediation, we may also be called upon to address these rest posture issues, and tongue thrust more aggressively together. In this process, facial growth and development and jaw structure may coincidentally improve as a result of 'nature taking its course' by addressing both swallow AND rest posture. In a select subset of clients, dramatic improvements may occur if the timing is right. This article discusses one such case that appears to have yielded a significant improvement in oral postures influencing improved facial and oral growth and development.
Porter, Laura S; Pollak, Kathryn I; Farrell, David; Cooper, Meredith; Arnold, Robert M; Jeffreys, Amy S; Tulsky, James A
2015-10-01
Patients often struggle to express their emotional concerns to their oncology providers and may therefore experience unmet needs. This paper describes the development and implementation of an online program that teaches patients how to communicate their emotions to their oncology providers. The intervention was developed by a multidisciplinary team consisting of palliative care physicians, psychologists, and an intervention software developer and included input from patients. It incorporated elements of Social Cognitive Theory and validated cognitive behavioral strategies for communication skills training. Strategies to increase intervention adherence were implemented midway through the study. The intervention consists of four interactive, online modules to teach patients strategies for expressing emotional concerns to their providers and asking for support. In addition to skill-building, the intervention was designed to raise patients' expectations that expressing emotional concerns to providers would be helpful, to enhance their self-efficacy for doing so, and to help them overcome barriers to having these conversations. After implementing strategies to improve adherence, usage rates increased from 47 to 64 %. This intervention addresses an unmet educational need for patients with advanced cancer. Strategies to increase adherence led to improvements in usage rates in this population of older patients. We are currently evaluating the intervention in a randomized clinical trial to determine its efficacy in increasing patient expression of emotional concerns and requests for support. If successful, this intervention could serve as a model for future online patient education programs.
Porter, Laura S.; Pollak, Kathryn I.; Farrell, David; Cooper, Meredith; Arnold, Robert M.; Jeffreys, Amy S.; Tulsky, James A.
2015-01-01
Purpose Patients often struggle to express their emotional concerns to their oncology providers, and may therefore experience unmet needs. This paper describes the development and implementation of an online program that teaches patients how to communicate their emotions to their oncology providers. Methods The intervention was developed by a multidisciplinary team consisting of palliative care physicians, psychologists, and an intervention software developer, and included input from patients. It incorporated elements of Social Cognitive Theory and validated cognitive behavioral strategies for communication skills training. Strategies to increase intervention adherence were implemented midway through the study. Results The intervention consists of four interactive, online modules to teach patients strategies for expressing emotional concerns to their providers and asking for support. In addition to skill-building, the intervention was designed to raise patients’ expectations that expressing emotional concerns to providers would be helpful, to enhance their self-efficacy for doing so, and to help them overcome barriers to having these conversations. After implementing strategies to improve adherence, usage rates increased from 47% to 64%. Conclusions This intervention addresses an unmet educational need for patients with advanced cancer. Strategies to increase adherence led to improvements in usage rates in this population of older patients. We are currently evaluating the intervention in a randomized clinical trial to determine its efficacy in increasing patient expression of emotional concerns and requests for support. If successful, this intervention could serve as a model for future online patient education programs. PMID:25701437
Natural Language Processing: Toward Large-Scale, Robust Systems.
ERIC Educational Resources Information Center
Haas, Stephanie W.
1996-01-01
Natural language processing (NLP) is concerned with getting computers to do useful things with natural language. Major applications include machine translation, text generation, information retrieval, and natural language interfaces. Reviews important developments since 1987 that have led to advances in NLP; current NLP applications; and problems…
There are many concerns and challenges in current remediation strategies for sediments contaminated with polychlorinated biphenyls (PCBs). Our efforts have been geared toward the development of granular activated carbon (GAC) impregnated with reactive iron/palladium (Fe/Pd) bime...
Taking the High Road: Teaching for Transfer in an FYC Program
ERIC Educational Resources Information Center
Fishman, Jenn; Reiff, Mary Jo
2008-01-01
Current theoretical conversations in the field of Rhetoric and Composition, particularly conversations related to first-year curricular design, are increasingly concerned with the issue of "teaching for transfer." While developing successful transfer pedagogy is a challenging undertaking, one that may require writing instructors to…
ERIC Educational Resources Information Center
Wickwire, Pat Nellor, Ed.
1999-01-01
This publication of the California Association for Counseling and Development for 1998-1999 supports the organizational goals of leadership, inquiry, discovery, excellence, and innovation. It attempts to identify the current issues of concern in the counseling field and to share research to help improve the professional learning community. As a…
PASSwrite: Recalibrating Student Academic Literacies Development
ERIC Educational Resources Information Center
Williamson, Frances; Goldsmith, Rosalie
2013-01-01
Concern about student retention and success remains paramount in universities both in Australia and overseas, especially in the light of the ongoing massification of higher education, yet current strategies are not necessarily dealing successfully with the changing demographics of student populations. This is particularly so in the realm of…
Adolescence: Guiding Youth through the Perilous Ordeal. First Edition.
ERIC Educational Resources Information Center
Newton, Miller
Adolescence is becoming an increasingly dangerous time of life, with increased violent deaths, juvenile delinquency, and sexual activity. Designed for therapists in psychology, social work, school psychology, family therapy, guidance counseling, and other areas, this book outlines current knowledge concerning adolescent development, along with the…
Postgraduate Training in Student Learning and Teaching.
ERIC Educational Resources Information Center
Alpay, E.; Mendes-Tatsis, M. A.
2000-01-01
Presents an experiential postgraduate training program for student learning and supervision involving laboratory and pilot plant supervisions in the chemical engineering field. The program addresses some of the current concerns about non-technical training and the further development of the broad science and engineering knowledge of postgraduate…
Educational Challenges of the 80's.
ERIC Educational Resources Information Center
Carroll, Constance M.
Growing conservatism, dwindling resources, and the increased diversity of students require that the California community colleges develop a plan to meet the challenges of the future. First, efforts must be made to ameliorate the current crisis in educational leadership caused by excessive concern with quantitative management techniques, reporting…
Social Bonds and Internet Pornographic Exposure among Adolescents
ERIC Educational Resources Information Center
Mesch, Gustavo S.
2009-01-01
Concern has grown regarding possible harm to the social and psychological development of children and adolescents exposed to Internet pornography. Parents, academics and researchers have documented pornography from the supply side, assuming that its availability explains consumption satisfactorily. The current paper explored the user's dimension,…
An Exploration of African American Students' Attitudes toward Online Learning
ERIC Educational Resources Information Center
Okwumabua, Theresa M.; Walker, Kristin M.; Hu, Xiangen; Watson, Andrea
2011-01-01
The current work presents exploratory research findings concerning African American students' attitudes toward online learning. The Online Tutoring Attitudes Scale (OTAS; Graff, 2003) was administered to 124 African American students in a positive youth development program. Findings suggest that African American students' attitudes toward…
Evaluation of Educator & Student Use of & Attitudes toward Dissection & Dissection Alternatives
ERIC Educational Resources Information Center
Osenkowski, Pamela; Green, Che; Tjaden, Anne; Cunniff, Peggy
2015-01-01
Animal dissection has been routinely practiced in American biology classrooms for decades. With technological advancements, more states adopting student choice measures, and increased awareness about ethical concerns surrounding dissection, many useful dissection alternatives have been developed. To understand the current use of animal dissection…
Johnston, Rory; Adams, Krystyna; Bishop, Lisa; Crooks, Valorie A; Snyder, Jeremy
2015-02-03
Many countries have demonstrated interest in expanding their medical tourism sectors because of its potential economic and health system benefits. However, medical tourism poses challenges to the equitable distribution of health resources between international and local patients and private and public medical facilities. Currently, very little is known about how medical tourism is perceived among front line workers and users of health systems in medical tourism 'destinations'. Barbados is one such country currently seeking to expand its medical tourism sector. Barbadian nurses and health care users were consulted about the challenges and benefits posed by ongoing medical tourism development there. Focus groups were held with two stakeholder groups in May, 2013. Nine (n = 9) citizens who use the public health system participated in the first focus group and seven (n = 7) nurses participated in the second. Each focus group ran for 1.5 hours and was digitally recorded. Following transcription, thematic analysis of the digitally coded focus group data was conducted to identify cross-cutting themes and issues. Three core concerns regarding medical tourism's health equity impacts were raised; its potential to 1) incentivize migration of health workers from public to private facilities, 2) burden Barbados' lone tertiary health care centre, and 3) produce different tiers of quality of care within the same health system. These concerns were informed and tempered by the existing a) health system structure that incorporates both universal public healthcare and a significant private medical sector, b) international mobility among patients and health workers, and c) Barbados' large recreational tourism sector, which served as the main reference in discussions about medical tourism's impacts. Incorporating these concerns and contextual influences, participants' shared their expectations of how medical tourism should locally develop and operate. By engaging with local health workers and users, we begin to unpack how potential health equity impacts of medical tourism in an emerging destination are understood by local stakeholders who are not directing sector development. This further outlines how these groups employ knowledge from their home context to ground and reconcile their hopes and concerns for the impacts posed by medical tourism.
Improving aircraft energy efficiency
NASA Technical Reports Server (NTRS)
Povinelli, F. P.; Klineberg, J. M.; Kramer, J. J.
1976-01-01
Investigations conducted by a NASA task force concerning the development of aeronautical fuel-conservation technology are considered. The task force estimated the fuel savings potential, prospects for implementation in the civil air-transport fleet, and the impact of the technology on air-transport fuel use. Propulsion advances are related to existing engines in the fleet, to new production of current engine types, and to new engine designs. Studies aimed at the evolutionary improvement of aerodynamic design and a laminar flow control program are discussed and possibilities concerning the use of composite structural materials are examined.
Use of Statins in Patients with Chronic Liver Disease and Cirrhosis: Current Views and Prospects.
Vargas, Jose Ignacio; Arrese, Marco; Shah, Vijay H; Arab, Juan Pablo
2017-09-01
The purpose of this study is to analyze the current evidence regarding the use of statins in patients with chronic liver disease and cirrhosis. Chronic liver disease (CLD), cirrhosis, and its complications, including hepatocellular carcinoma (HCC), are significant public health problems. The use of statins in patients with CLD has been a matter of concern, and physicians are often reluctant to its prescription in these patients. This mainly relates to the potential occurrence of drug-induced liver injury. However, newer evidence from pre-clinical and clinical research has shown that statins are drugs with a potentially beneficial impact on the natural history of cirrhosis, on portal hypertension, and in HCC prevention. In this review, we summarize current evidence regarding the influence of statins in endothelial dysfunction in CLD, their ability to modulate hepatic fibrogenesis, and their vasoprotective effects in portal hypertension; we also focus on existing data about the impact of statins in cirrhosis development, progression, and complications and critically assess the current concerns about its use in patients with CLD.
Vitamin D in adolescents: Are current recommendations enough?
Smith, Taryn J; Lanham-New, Susan A; Hart, Kathryn H
2017-10-01
Vitamin D is essential for bone development during adolescence and low vitamin D status during this critical period of growth may impact bone mineralization, potentially reducing peak bone mass and consequently increasing the risk of osteoporosis in adulthood. Therefore, the high prevalence of vitamin D inadequacy and deficiency in adolescent populations is of great concern. However, there is currently a lack of consensus on the 25-hydroxyvitamin D [25(OH)D] concentration, the widely accepted biomarker of vitamin D status, that defines adequacy, and the vitamin D intake requirements to maintain various 25(OH)D thresholds are not well established. While the current intake recommendations of 10-15μg/day may be sufficient to prevent vitamin D deficiency (25(OH)D<25-30nmol/l), greater intakes may be needed to achieve the higher threshold levels proposed to represent adequacy (25(OH)D>50nmol/l). This review will address these concerns and consider if the current dietary recommendations for vitamin D in adolescents are sufficient. Crown Copyright © 2017. Published by Elsevier Ltd. All rights reserved.
Leveraging Facebook to Brand Radiology.
Tso, Hilda H; Parikh, Jay R
2018-03-30
In the current health care climate, radiologists should consider developing their brand. Facebook is the market leader for social media networking in the United States. The authors describe how radiologists can leverage Facebook to develop and market organizational, group, and individual brands. The authors then address concerns related to the use of social media by radiologists. Copyright © 2018 American College of Radiology. Published by Elsevier Inc. All rights reserved.
ERIC Educational Resources Information Center
British Council, London (England).
Proceedings of a seminar on the role of English second language (ELT) training in British technical assistance projects for economic development are presented in the form of a brief analysis of current issues and concerns to participants, a summary of the conference, and related appended materials. This conference focused on defining project…
Wave energy: a Pacific perspective.
Paasch, Robert; Ruehl, Kelley; Hovland, Justin; Meicke, Stephen
2012-01-28
This paper illustrates the status of wave energy development in Pacific rim countries by characterizing the available resource and introducing the region's current and potential future leaders in wave energy converter development. It also describes the existing licensing and permitting process as well as potential environmental concerns. Capabilities of Pacific Ocean testing facilities are described in addition to the region's vision of the future of wave energy.
ERIC Educational Resources Information Center
Noss, Richard
This document, the second part of the third volume of a study concerned with the role of institutions of higher education in the development of countries in South-East Asia, discusses the problems aroused by language in the region. Chapters I-IV cover assumptions of the study, common problems of the region, current solutions, and future outlook.…
ERIC Educational Resources Information Center
Council of Ontario Universities, Toronto.
This brief was submitted to the Standing Committee on Social Development of the Ontario Legislature in connection with Bill 42, which is intended to limit university deficits. The following concerns are examined: current university funding levels in relation to enrollment and student demand, research responsibilities, tuition fee levels, and…
The Perfect Womb: Promoting Equality of (Fetal) Opportunity.
Kendal, Evie
2017-06-01
This paper aims to address how artificial gestation might affect equality of opportunity for the unborn and any resultant generation of "ectogenetic" babies. It will first explore the current legal obstacles preventing the development of ectogenesis, before looking at the benefits of allowing this technology to control fetal growth and development. This will open up a discussion of the treatment/enhancement divide regarding the use of reproductive technologies, a topic featured in various bioethical debates on the subject. Using current maternity practices in Western society as a comparator, this paper will conclude that neither naturally nor artificially gestated fetuses have interests that can conflict with those of potential parents who might want to use this technology to control fetal development. Such control may include selective implantation of embryos of a desired gender, deliberate choice of genetic traits, or maintenance of an ideal incubation environment to avoid fetal damage. Objections on the basis of disability as well as concerns regarding eugenics will be addressed. The paper will conclude that none of these objections are compelling grounds to prevent the development and use of ectogenesis technologies for the purpose of achieving specific reproductive goals, particularly when compared to current practices in pre-implantation genetic diagnosis and selective abortion on the grounds of undesired traits. As such, when deciding whether to support ectogenesis research, the enduring interests of parents must be the primary consideration, with societal concerns regarding potential misuse the only valid secondary consideration.
Antidepressants and the adolescent brain.
Cousins, Lesley; Goodyer, Ian M
2015-05-01
Major unipolar depression is a significant global health problem, with the highest incident risk being during adolescence. A depressive illness during this period is associated with negative long-term consequences including suicide, additional psychiatric comorbidity, interpersonal relationship problems, poor educational performance and poor employment attainment well into adult life. Despite previous safety concerns, selective serotonin reuptake inhibitors (SSRIs) remain a key component of the treatment of moderate to severe depression episodes in adolescents. The impact of SSRIs on the developing adolescent brain, however, remains unclear. In this review we first consider what is currently known about the developing brain during adolescence and how these development processes may be affected by a depressive illness. We then review our understanding of the action of SSRIs, their effects on the brain and how these may differ between adults and adolescents. We conclude that there is currently little evidence to indicate that the human adolescent brain is at developmental risk from SSRIs. Furthermore, there is no clear-cut evidence to support the concerns of marked suicidal adverse side effects accruing in depressed adolescents being treated with SSRIs. Neither, however, is there irrefutable evidence to dismiss all such concerns. This makes SSRI prescribing a matter of medical judgement, ensuring the benefits outweigh the risks for the individual patients, as with so much in therapeutics. Overall, SSRIs show clinical benefits that we judge to outweigh the risks to neurodevelopment and are an important therapeutic choice in the treatment of moderate to severe adolescent depression. © The Author(s) 2015.
Current challenges in the development of vaccines for pneumonic plague
Smiley, Stephen T
2008-01-01
Inhalation of Yersinia pestis bacilli causes pneumonic plague, a rapidly progressing and exceptionally virulent disease. Extensively antibiotic-resistant Y. pestis strains exist and we currently lack a safe and effective pneumonic plague vaccine. These facts raise concern that Y. pestis may be exploited as a bioweapon. Here, I review the history and status of plague vaccine research and advocate that pneumonic plague vaccines should strive to prime both humoral and cellular immunity. PMID:18324890
Current Topics in Canine and Feline Obesity.
Hamper, Beth
2016-09-01
The domestication and urbanization of dogs and cats has dramatically altered their environment and behavior. Human and pet obesity is a global concern, particularly in developed countries. An increased incidence of chronic disease is associated with obesity secondary to low-grade systemic inflammation. This article reviews current research into the genetic, dietary, and physiologic factors associated with obesity, along with use of "omics" technology to better understand and characterize this disease. Copyright © 2016 Elsevier Inc. All rights reserved.
Malaria on the Guiana Shield: a review of the situation in French Guiana
Musset, Lise; Pelleau, Stéphane; Girod, Romain; Ardillon, Vanessa; Carvalho, Luisiane; Dusfour, Isabelle; Gomes, Margarete SM; Djossou, Félix; Legrand, Eric
2014-01-01
In a climate of growing concern that Plasmodium falciparum may be developing a drug resistance to artemisinin derivatives in the Guiana Shield, this review details our current knowledge of malaria and control strategy in one part of the Shield, French Guiana. Local epidemiology, test-treat-track strategy, the state of parasite drug resistance and vector control measures are summarised. Current issues in terms of mobile populations and legislative limitations are also discussed. PMID:25184998
Privacy and the Private Eye in Space.
ERIC Educational Resources Information Center
Smith, William E.
Land remote-sensing satellites are developing as a commercial communications technology after years under a government monopoly. The shift to the private sector and improving quality of the pictures produced have given rise to increased concerns about the potential for violations of privacy rights. Although satellites can currently photograph only…
Transforming the University Campus into a Sustainable Community
ERIC Educational Resources Information Center
Norton, Richard K.; Brix, Andrew; Brydon, Trevor; Davidian, Elijah; Dinse, Keely; Vidyarthi, Sanjeev
2007-01-01
This study addresses several common shortcomings of current university campus sustainability initiatives, including a lack of attention to integrative issues such as land use, housing, and transportation, and a generally reactive rather than proactive approach to sustainability. To engage these concerns, we develop a model for assessing the…
Developing Personalised Education for Personal Mobile Technologies with the Pluralisation Agenda
ERIC Educational Resources Information Center
Kucirkova, Natalia; Littleton, Karen
2017-01-01
This paper makes a distinctive contribution to the current debates concerning the role of personal mobile technologies (PMTs) in public education. It does this through drawing attention to the imperative to integrate digitally-mediated personalised education with teacher-mediated pluralised education. Premised on the notion that children's…
Questioning Intuition through Reflective Engagement
ERIC Educational Resources Information Center
Schmidt, Christopher D.
2014-01-01
Current literature on ethics and moral development focuses on discussion concerning the impact of intuition on moral decision-making. Through the use of student journal reflections over the course of one semester, this study utilized a grounded theory approach in order to explore and understand participant levels of awareness and understanding of…
[Radiological dose and metadata management].
Walz, M; Kolodziej, M; Madsack, B
2016-12-01
This article describes the features of management systems currently available in Germany for extraction, registration and evaluation of metadata from radiological examinations, particularly in the digital imaging and communications in medicine (DICOM) environment. In addition, the probable relevant developments in this area concerning radiation protection legislation, terminology, standardization and information technology are presented.
Teachers' Perceptions of a Community Participation Programme for Preschoolers with Autism
ERIC Educational Resources Information Center
Mak, Candice; Zhang, Kaili Chen
2013-01-01
Preschoolers with autism face a number of challenges in integrating into different community activities owing to behavioural, communication and emotional concerns. Since the year 2009, the Hong Kong Heep Hong Society has developed a training programme for enhancing community participation among individuals with autism. The current project reports…
The Missing Disciplinary Substance of Formative Assessment
ERIC Educational Resources Information Center
Coffey, Janet E.; Hammer, David; Levin, Daniel M.; Grant, Terrance
2011-01-01
We raise concerns about the current state of research and development in formative assessment, specifically to argue that in its concentration on "strategies for the teacher", the literature overlooks the "disciplinary substance" of what teachers and students assess. Our argument requires analysis of specific instances in the literature, and so we…
Effects of Marijuana on Fetal Development.
ERIC Educational Resources Information Center
Hoyt, Les Leanne
1981-01-01
Presents an historical perspective of the public view of marijuana and examines current empirical research concerning the consequences of marijuana use on the human fetus. Included are 1979 university survey results which explore respondents' knowledge about the effects of marijuana and the relationship this has to the mass media. (Author)
Physics Teachers' Perceptions of the Difficulty of Teaching Electricity
ERIC Educational Resources Information Center
Gunstone, Richard; Mulhall, Pamela; McKittrick, Brian
2009-01-01
As part of a project concerned with developing a better understanding of the detail of appropriate teaching of direct current (DC) electricity concepts, extensive individual interviews were conducted with a number of experienced senior high school physics teachers. These interviews explored teachers' perceptions of difficulties in student learning…
NEW TECHNOLOGIES TO SOLVE OLD PROBLEMS AND ADDRESS ISSUES IN RISK ASSESSMENT
Appropriate utilization of data is an ongoing concern of the regulated industries and the agencies charged with assessing safety or risk. An area of current interest is the possibility that toxicogenomics will enhance our ability to develop higher or high-throughput models for pr...
International and Citizenship Education: Need and Nexus.
ERIC Educational Resources Information Center
Branson, Margaret Stimmann
Two major efforts to redirect the school curriculum that are currently of special concern, not only to educators but to the general citizenry as well, are citizenship education and international or global education. Both deal with the development of competent and responsible citizens whose perspectives, knowledge, and skills will enable them to…
Federal Information Policies in the 1990s: Views and Perspectives.
ERIC Educational Resources Information Center
Hernon, Peter, Ed.; And Others
This book uses a cross-disciplinary approach to profile developments through November 1995 concerning important U.S. government information policy issues. Information policy analyses benefit from a historical perspective while seeking to identify current areas of agreement and disagreement, especially at a time when the United States is moving…
Law-and-Education Research: Past and Future.
ERIC Educational Resources Information Center
Yudof, Mark G.
1979-01-01
The author traces the development of this new field of legal study concerning the interface of law and educational policy. Finding the field's current approach misdirected through overemphasis on reform and the Constitution, he suggests a new paradigm, law-in-action, with a broader focus drawn from related disciplines. (SJL)
Gas alternatives to carbon dioxide for euthanasia: A piglet perspective
USDA-ARS?s Scientific Manuscript database
The identification and validation of a humane method to euthanize piglets is critical to address concern that current methods are not acceptable. This research sought to: 1) identify a method of scientifically determining if pigs find a specific euthanasia method aversive, and 2) develop an innovati...
Ankerl, G
1983-01-01
A review of current urbanization trends around the world is presented, with particular reference to the situation in Tropical Africa. Topics considered include overurbanization, development, and migration. The elements of both short- and long-term policies concerning urbanization are outlined.
Public Schools and the Juvenile Justice System: Facilitating Relationships
ERIC Educational Resources Information Center
Mazzotti, Valerie L.; Higgins, Kyle
2006-01-01
This article describes the importance of facilitating relationships between schools and the Juvenile Justice System. Emphasis is placed on statistics concerning children/youth involved in the Juvenile Justice System and the current state of school programs. Strategies for developing integrated programs between schools and the Juvenile Justice…
ERIC Educational Resources Information Center
Scottish Educational Studies, 1977
1977-01-01
This first report--necessarily a selective account--is an attempt to give a broad view of current developmental work in the field of language, increasingly a focus of concern in these post-bullock times. (Editor)
Deployment and evaluation of an active RFID tracking system for finishing pigs
USDA-ARS?s Scientific Manuscript database
Modern swine facilities were developed mainly based on logistics of feeding and moving animals. In recent years, the public has become increasingly concerned about animal care and well-being. A better understanding of the animal space utilization in current facilities could lead to improved facilit...
DOT National Transportation Integrated Search
2010-12-01
The current climate crisis and recent world events, including a global economic crisis and growing concerns over the availability and cost of petroleum fuels, has sparked a global interest in developing alternative, sustainable, clean fuel technologi...
The Role of Evaluation and Plans for Evaluating the Current Testing Program.
ERIC Educational Resources Information Center
Winters, Lynn
The Palos Verdes Peninsula Unified School District Office of Program Evaluation and Research is responsible for providing information for program development and improvement; providing test information to special programs coordinators; and acting as a clearinghouse for all information concerning tests, evaluation methodology, and educational…
There is considerable public concern that the majority of commercial chemicals have not been evaluated for their potential to cause developmental neurotoxicity. Although several chemicals are assessed annually under the current developmental neurotoxicity guidelines, time, resour...
Brave Forms of Mentoring Supported by Technology in Teacher Education
ERIC Educational Resources Information Center
Charbonneau-Gowdy, Paula; Capredoni, Rosana; Gonzalez, Sebastian; Jayo, María José; Raby, Pablo
2016-01-01
Quality education is undoubtedly a global concern, tied closely to preoccupations with economic and social development. Increasingly, the adoption and effective use of current technology tools are being recognized as visible signs of that quality. Scholars are providing increasing evidence of the kinds of empowered teacher identities that will…
Helping the Underachiever in Reading. ERIC Digest.
ERIC Educational Resources Information Center
Quatroche, Diana J.
Noting that the development of effective intervention programs and instructional strategies for the struggling or underachieving reader continues to be a topic of concern, this Digest first reviews the current status of reading performance, based on the 1998 National Assessment of Educational Progress. It then reports on the importance of early…
Back to the Future: Anticipating and Preparing for Change.
ERIC Educational Resources Information Center
Lapin, Joel D.
1992-01-01
Explains how colleges can take control of their futures by anticipating needs and demands. Describes environmental scanning, a way of identifying future concerns based on current trends and emerging issues. Provides examples of colleges that used forecasting and scanning to develop new courses and refine mission statements. (DMM)
Building Public Health Capacity through Online Global Learning
ERIC Educational Resources Information Center
Madhok, Rajan; Frank, Erica; Heller, Richard Frederick
2018-01-01
Rising disease burden and health inequalities remain global concerns, highlighting the need for health systems strengthening with a sufficient and appropriately trained workforce. The current models for developing such a workforce are inadequate and newer approaches are needed. In this paper we describe a model for public health capacity building…
A Comparative Survey of Education Systems: Structure, Organization and Development.
ERIC Educational Resources Information Center
King, Edmund
1990-01-01
Education must disengage from current accountancy concerns and serve learners now and in their real contexts. The massive efficiency of our industrialized apparatus for processing people in formal education prevents us from recognizing that a new approach is needed to satisfy tomorrow's uncertain and unlimited requirements. An international…
Library Systems: Current Developments and Future Directions.
ERIC Educational Resources Information Center
Healy, Leigh Watson
This report was commissioned in response to concerns expressed about the gap between institutional digital library initiatives and the products offered by library systems vendors. The study analyzes from the perspective of libraries the strategies, visions, and products that vendors of integrated library systems are offering as solutions. Case…
Some Current Problems in Simulator Design, Testing and Use.
ERIC Educational Resources Information Center
Caro, Paul W.
Concerned with the general problem of the effectiveness of simulator training, this report reflects information developed during the conduct of aircraft simulator training research projects sponsored by the Air Force, Army, Navy, and Coast Guard. Problems are identified related to simulator design, testing, and use, all of which impact upon…
Three In-Course Assessment Reforms to Improve Higher Education Learning Outcomes
ERIC Educational Resources Information Center
Sadler, D. Royce
2016-01-01
A current international concern is that, for too large a proportion of graduates, their higher order cognitive and practical capabilities are below acceptable levels. The constituent courses of academic programmes are the most logical sites for developing these capabilities. Contributing to patchy attainment are deficiencies in three particular…
Personalizing health care: feasibility and future implications.
Godman, Brian; Finlayson, Alexander E; Cheema, Parneet K; Zebedin-Brandl, Eva; Gutiérrez-Ibarluzea, Inaki; Jones, Jan; Malmström, Rickard E; Asola, Elina; Baumgärtel, Christoph; Bennie, Marion; Bishop, Iain; Bucsics, Anna; Campbell, Stephen; Diogene, Eduardo; Ferrario, Alessandra; Fürst, Jurij; Garuoliene, Kristina; Gomes, Miguel; Harris, Katharine; Haycox, Alan; Herholz, Harald; Hviding, Krystyna; Jan, Saira; Kalaba, Marija; Kvalheim, Christina; Laius, Ott; Lööv, Sven-Ake; Malinowska, Kamila; Martin, Andrew; McCullagh, Laura; Nilsson, Fredrik; Paterson, Ken; Schwabe, Ulrich; Selke, Gisbert; Sermet, Catherine; Simoens, Steven; Tomek, Dominik; Vlahovic-Palcevski, Vera; Voncina, Luka; Wladysiuk, Magdalena; van Woerkom, Menno; Wong-Rieger, Durhane; Zara, Corrine; Ali, Raghib; Gustafsson, Lars L
2013-08-13
Considerable variety in how patients respond to treatments, driven by differences in their geno- and/ or phenotypes, calls for a more tailored approach. This is already happening, and will accelerate with developments in personalized medicine. However, its promise has not always translated into improvements in patient care due to the complexities involved. There are also concerns that advice for tests has been reversed, current tests can be costly, there is fragmentation of funding of care, and companies may seek high prices for new targeted drugs. There is a need to integrate current knowledge from a payer's perspective to provide future guidance. Multiple findings including general considerations; influence of pharmacogenomics on response and toxicity of drug therapies; value of biomarker tests; limitations and costs of tests; and potentially high acquisition costs of new targeted therapies help to give guidance on potential ways forward for all stakeholder groups. Overall, personalized medicine has the potential to revolutionize care. However, current challenges and concerns need to be addressed to enhance its uptake and funding to benefit patients.
Personalizing health care: feasibility and future implications
2013-01-01
Considerable variety in how patients respond to treatments, driven by differences in their geno- and/ or phenotypes, calls for a more tailored approach. This is already happening, and will accelerate with developments in personalized medicine. However, its promise has not always translated into improvements in patient care due to the complexities involved. There are also concerns that advice for tests has been reversed, current tests can be costly, there is fragmentation of funding of care, and companies may seek high prices for new targeted drugs. There is a need to integrate current knowledge from a payer’s perspective to provide future guidance. Multiple findings including general considerations; influence of pharmacogenomics on response and toxicity of drug therapies; value of biomarker tests; limitations and costs of tests; and potentially high acquisition costs of new targeted therapies help to give guidance on potential ways forward for all stakeholder groups. Overall, personalized medicine has the potential to revolutionize care. However, current challenges and concerns need to be addressed to enhance its uptake and funding to benefit patients. PMID:23941275
ERIC Educational Resources Information Center
Alhomairi, Abdulqadir Obaidallah A.
2018-01-01
Saudi Arabia's Vision for 2030 in development is exceedingly concerned with curriculum development. It believes that the current curriculum does no longer support the students' preparation for both life and work. Therefore, the present study aimed to reach a consensus by a set of educational experts on the importance of providing the science…
Necessary conditions for the globalization of traditional Chinese medicine.
Yu, Bei-Bei; Gong, Xiu-Lin
2011-03-01
With the current trend of globalization, unprecedented opportunities and enormous changes have emerged for the global development of traditional Chinese medicine (TCM). However, many old and new challenges and problems still remain, including partial or limited comprehension of acupuncture, oriental medicine and TCM, the existence of non-standardized institutes of TCM and acupuncture training schools, unqualified TCM practitioners, and problems concerning Chinese herbal medicine and inexperience in conducting TCM business. These problems will doubtlessly impede the further development of TCM worldwide in the foreseeable future. It is also clear that the globalization of TCM will require a large scale systematic project and constitute an arduous historical task. This paper aims to consolidate 6 strategic development modes to reinforce and facilitate the process of TCM globalization through a detailed analysis of both the present status and existing problems concerning the development of TCM in the United States.
Technoeconomic evaluation of urban plant factories: The case of basil (Ocimum basilicum).
Liaros, Stelios; Botsis, Konstantinos; Xydis, George
2016-06-01
Greece is currently in a turmoil, experiencing the effects of more than half a decade of economic crisis. Public health and welfare, jobs and wages, labor market concerning employment as long as employability of the work force, inequality, life satisfaction and housing, tourism and environment, economic and energy poverty are heavily impacted by Greece's disadvantageous economic situation. Real estate market could not have gotten away from the financial commotion, being currently in a halt after years of rapid decline. Fired from the present situation of Greece's real estate market, the present study is concerned with the investigation of alternative ways to support the local real estate market. With respect to sustainable development's ethics, the development, implementation, installation and operation of small, inexpensive plant factories within the urban environment is evaluated. Installations such are those, will encourage the penetration of a new market for the untapped buildings' resource, advancing new investing opportunities, promoting economic growth and productivity while creating a new labor market. The study will rely on the basic principles of Life Cycle Costing Assessment and develop a methodology upon which different scenarios will be evaluated against the "Do Nothing" scenario. Copyright © 2016 Elsevier B.V. All rights reserved.
Three-dimensionality development inside standard parallelepipedic lid-driven cavities at /Re=1000
NASA Astrophysics Data System (ADS)
Migeon, C.; Pineau, G.; Texier, A.
2003-04-01
This paper considers the problem of the time-dependent laminar incompressible flow motion within parallelepipedic cavities in which one wall moves with uniform velocity after an impulsive start using a particle-streak and a dye-emission techniques. Of particular concern is the examination of the spanwise structures of the flow in view to point out how three-dimensionality arises and develops with time for a Reynolds number of 1000. For this purpose, attention is focused on the spanwise currents, the end-wall corner vortices and the structures resulting from the centrifugal instability. Among others, the study clearly shows the scenario of propagation of the spanwise currents by giving quantitative information on their velocity and on the time from which a given cross-plane becomes affected by such a 3-D perturbation. Furthermore, the numerous visualizations reveal the existence of only one corner-vortex on each end-wall; this vortex is quasi-toroidal shaped. Finally, concerning flow instability, the present results show that no well-formed counter-rotating vortices emerge for /Re=1000 during the start-up phase contrary to what was asserted so far. However, two successive initial phases of this instability development are revealed for the first time.
Hemetek, U; Ernert, A; Wiegand, S; Bau, A-M
2015-11-01
The alarming increase in the prevalence of childhood obesity is recognised as a major public health concern. Currently, structured multi-modal therapy programmes present the gold standard of therapy strategies for obese children and adolescents. However, effects of these treatments are still a matter of discussion. Failure to isolate and understand the external and internal factors contributing to successful, long-term weight reduction may well be contributing to the ineffectiveness of current treatment interventions. A qualitative approach was chosen in order to identify subjectively perceived resources and barriers to weight maintenance after previous weight reduction. The research question focused on how these resources and barriers affect success of participants. Additionally the question arose as to how and to what extent parents should and could be involved in the therapy process. The results can deliver important starting points for the development of therapy programmes and future research. 7 participants of a weight reduction and maintenance programme and 7 of their parents were interviewed on their personal experiences during and after the treatment. The interviews were analysed based on the qualitative content analysis. Continuous motivation, especially after the initial weight reduction phase, was identified as the strongest predictor of successful weight maintenance. Successful weight maintainers generally showed characteristics of higher self-efficacy, internal motivation concerning physical activity and flexible self-control concerning food intake. Unsuccessful weight gainers stated a lack of motivation concerning physical activity and lost control over their eating habits. Concerning the role of parents in the therapy process, the results show that higher parental involvement does not predict greater success. The general relationship between parents and their children seems to be more significant, especially concerning the issues of responsibility. It is disputable to what extent the post treatment intervention contributed to the development of intrinsic motivation. More attention should be paid to the age (children or adolescents) of participants of therapy programmes, especially concerning the involvement of parents. It is assumed that general aspects of education should be discussed with parents. © Georg Thieme Verlag KG Stuttgart · New York.
Nanotechnology in food science: Functionality, applicability, and safety assessment.
He, Xiaojia; Hwang, Huey-Min
2016-10-01
Rapid development of nanotechnology is expected to transform many areas of food science and food industry with increasing investment and market share. In this article, current applications of nanotechnology in food systems are briefly reviewed. Functionality and applicability of food-related nanotechnology are highlighted in order to provide a comprehensive view on the development and safety assessment of nanotechnology in the food industry. While food nanotechnology offers great potential benefits, there are emerging concerns arising from its novel physicochemical properties. Therefore, the safety concerns and regulatory policies on its manufacturing, processing, packaging, and consumption are briefly addressed. At the end of this article, the perspectives of nanotechnology in active and intelligent packaging applications are highlighted. Copyright © 2016. Published by Elsevier B.V.
MAGNESIUM ALLOYS IN US MILITARY APPLICATIONS: PAST, CURRENT AND FUTURE SOLUTIONS
DOE Office of Scientific and Technical Information (OSTI.GOV)
Mathaudhu, Suveen N.; Nyberg, Eric A.
2010-02-26
Since the 1940’s Mg-alloys have been used for military applications, from aircraft components to ground vehicles. The drive for usage was primarily availability and lightweighting of military systems. But the promise of widespread military usage was not met largely based on corrosion and flammability concerns, poor mechanical behavior and inferior ballistic response. This review paper will cover historical, current and potential future applications with a focus on scientific, engineering and social barriers relevant to integration of Mg-alloy. It will also present mechanical and physical property improvements solutions which are currently being developed to address these issues.
A Few Examples of Spacecraft Anomalies Attributed to Transient Voltages and Currents Issues
NASA Technical Reports Server (NTRS)
Perez, Ray
2006-01-01
It is easy to address voltage and current transient related issues when the hardware in question or similar type of hardware is always available to you and when such issues are deterministic in nature. Unexpected or unforeseen transient related problems are not always a challenge but become a severe concern when a unique piece of the hardware, which developed the problem, is in space; as it is with all satellites. This paper addresses in a qualitative manner, a few examples of voltage and current events of transient origin which disabled space hardware.
Use of animals in the development and control of viral vaccines.
Minor, P D
1996-01-01
Animal models were central to the development of poliovaccines and remain essential in some form in the routine quality control of both live and killed vaccines. The necessity of an animal model is illustrated by the examples of mumps and measles vaccines where the existing materials, while satisfactory, have a number of drawbacks and where changes in current practice raise concerns for safety and efficacy.
Current perspectives in robotic assisted surgery.
Binet, Aurélien; Ballouhey, Quentin; Chaussy, Yann; de Lambert, Guénolée; Braïk, Karim; Villemagne, Thierry; Becmeur, François; Fourcade, Laurent; Lardy, Hubert
2018-02-23
From classical surgery to Robotic Assisted Surgery, there is a long way allowed by Minimal Invasive Surgery' improvements. The last three decades have witnessed a prodigious development of minimally invasive surgery (MIS) and especially in the field of laparoscopic pediatric surgery but there are several limitations in the use of conventional laparoscopic surgery and Robotic Assisted Surgery was developed to relieve these drawbacks. This new technology enables today the performance of a wide variety of procedures in children with a minimally invasive approach. As for all new technologies, an objective evaluation is essential with the need to respond to several questions: Is the technology feasible? Is the technology safe? Is the technology efficient? Does it bring about benefits compared with current technology? What are the procedures derived from most benefits of robotic assistance? How to assume the transition from open surgery to Minimal Invasive access for RAS? In the first part of this article, the authors give details about technical concerns and then describe the implementation process with its organization, pitfalls, successes, and issues from human resources and financial standpoints. The learning curve is then described and a special focus on small children weighing less than 15 Kg is developed. Finally, the concept of evaluation of this emerging technology is evocated and financial concerns are developed.
Recent Developments in Low-Level Lead Exposure and Intellectual Impairment in Children
Koller, Karin; Brown, Terry; Spurgeon, Anne; Levy, Len
2004-01-01
In the last decade children’s blood lead levels have fallen significantly in a number of countries, and current mean levels in developed countries are in the region of 3 μg/dL. Despite this reduction, childhood lead poisoning continues to be a major public health problem for certain at-risk groups of children, and concerns remain over the effects of lead on intellectual development in infants and children. The evidence for lowered cognitive ability in children exposed to lead has come largely from prospective epidemiologic studies. The current World Health Organization/Centers for Disease Control and Prevention blood level of concern reflects this and stands at 10 μg/dL. However, a recent study on a cohort of children whose lifetime peak blood levels were consistently < 10 μg/dL has extended the association of blood lead and intellectual impairment to lower levels of lead exposure and suggests there is no safety margin at existing exposures. Because of the importance of this finding, we reviewed this study in detail along with other recent developments in the field of low-level lead exposure and children’s cognitive development. We conclude that these findings are important scientifically, and efforts should continue to reduce childhood exposure. However, from a public health perspective, exposure to lead should be seen within the many other risk factors impacting on normal childhood development, in particular the influence of the learning environment itself. Current lead exposure accounts for a very small amount of variance in cognitive ability (1–4%), whereas social and parenting factors account for 40% or more. PMID:15198918
2012-01-01
Background In recent years, computer simulation models have supported development of pandemic influenza preparedness policies. However, U.S. policymakers have raised several concerns about the practical use of these models. In this review paper, we examine the extent to which the current literature already addresses these concerns and identify means of enhancing the current models for higher operational use. Methods We surveyed PubMed and other sources for published research literature on simulation models for influenza pandemic preparedness. We identified 23 models published between 1990 and 2010 that consider single-region (e.g., country, province, city) outbreaks and multi-pronged mitigation strategies. We developed a plan for examination of the literature based on the concerns raised by the policymakers. Results While examining the concerns about the adequacy and validity of data, we found that though the epidemiological data supporting the models appears to be adequate, it should be validated through as many updates as possible during an outbreak. Demographical data must improve its interfaces for access, retrieval, and translation into model parameters. Regarding the concern about credibility and validity of modeling assumptions, we found that the models often simplify reality to reduce computational burden. Such simplifications may be permissible if they do not interfere with the performance assessment of the mitigation strategies. We also agreed with the concern that social behavior is inadequately represented in pandemic influenza models. Our review showed that the models consider only a few social-behavioral aspects including contact rates, withdrawal from work or school due to symptoms appearance or to care for sick relatives, and compliance to social distancing, vaccination, and antiviral prophylaxis. The concern about the degree of accessibility of the models is palpable, since we found three models that are currently accessible by the public while other models are seeking public accessibility. Policymakers would prefer models scalable to any population size that can be downloadable and operable in personal computers. But scaling models to larger populations would often require computational needs that cannot be handled with personal computers and laptops. As a limitation, we state that some existing models could not be included in our review due to their limited available documentation discussing the choice of relevant parameter values. Conclusions To adequately address the concerns of the policymakers, we need continuing model enhancements in critical areas including: updating of epidemiological data during a pandemic, smooth handling of large demographical databases, incorporation of a broader spectrum of social-behavioral aspects, updating information for contact patterns, adaptation of recent methodologies for collecting human mobility data, and improvement of computational efficiency and accessibility. PMID:22463370
Developmental Neurotoxicology: History and Outline of ...
The present work provides a brief review of basic concepts in developmental neurotoxicology, as well as current representative testing guidelines for evaluating developmental neurotoxicity (DNT) of xenobiotics. Historically, DNT was initially recognized as a “functional” teratogenicity: the main concern was that prenatal and/or early postnatal exposures to chemicals during critical periods of central nervous system (CNS) development would cause later functional abnormalities of the brain. Current internationally harmonized DNT study guidelines are thus intended to predict adverse effects of test compounds on the developing CNS by observing such postnatal parameters as motor activity, startle response, and learning and memory, as well as neropathological alterations. The reliability of current DNT study guidelines and sensitivity of testing methodologies recommended in these guidelines have been confirmed by retrospective evaluations of the many international and domestic collaborative validation studies in developed nations including Japan. Invited review with brief review of basic concepts in developmental neurotoxicology, as well as current representative testing guidelines for evaluating developmental neurotoxicity (DNT) of xenobiotics.
Practical cryptographic strategies in the post-quantum era
NASA Astrophysics Data System (ADS)
Kabanov, I. S.; Yunusov, R. R.; Kurochkin, Y. V.; Fedorov, A. K.
2018-02-01
Quantum key distribution technologies promise information-theoretic security and are currently being deployed in com-mercial applications. We review new frontiers in information security technologies in communications and distributed storage applications with the use of classical, quantum, hybrid classical-quantum, and post-quantum cryptography. We analyze the cur-rent state-of-the-art, critical characteristics, development trends, and limitations of these techniques for application in enterprise information protection systems. An approach concerning the selection of practical encryption technologies for enterprises with branched communication networks is discussed.
Standardising Responsibility? The Significance of Interstitial Spaces.
Wickson, Fern; Forsberg, Ellen-Marie
2015-10-01
Modern society is characterised by rapid technological development that is often socially controversial and plagued by extensive scientific uncertainty concerning its socio-ecological impacts. Within this context, the concept of 'responsible research and innovation' (RRI) is currently rising to prominence in international discourse concerning science and technology governance. As this emerging concept of RRI begins to be enacted through instruments, approaches, and initiatives, it is valuable to explore what it is coming to mean for and in practice. In this paper we draw attention to a realm that is often backgrounded in the current discussions of RRI but which has a highly significant impact on scientific research, innovation and policy-namely, the interstitial space of international standardization. Drawing on the case of nanoscale sciences and technologies to make our argument, we present examples of how international standards are already entangled in the development of RRI and yet, how the process of international standardization itself largely fails to embody the norms proposed as characterizing RRI. We suggest that although current models for RRI provide a promising attempt to make research and innovation more responsive to societal needs, ethical values and environmental challenges, such approaches will need to encompass and address a greater diversity of innovation system agents and spaces if they are to prove successful in their aims.
Polydiacetylene-Based Liposomes: An "Optical Tongue" for Bacteria Detection and Identification
ERIC Educational Resources Information Center
West, Matthew R.; Hanks, Timothy W.; Watson, Rhett T.
2009-01-01
Food- and water-borne bacteria are a major health concern worldwide. Current detection methods are time-consuming and require sophisticated equipment that is not always readily available. However, new techniques based on nanotechnology are under development that will result in a new generation of sensors. In this experiment, liposomes are…
Plugged In: Electronics Use in Youth and Young Adults with Autism Spectrum Disorder
ERIC Educational Resources Information Center
MacMullin, Jennifer A.; Lunsky, Yona; Weiss, Jonathan A.
2016-01-01
Although electronic technology currently plays an integral role for most youth, there are growing concerns of its excessive and compulsive use. This study documents patterns and impact of electronics use in individuals with autism spectrum disorder compared to typically developing peers. Participants included 172 parents of typically developing…
Education, Fair Competition, and Concern for the Worst Off
ERIC Educational Resources Information Center
Giesinger, Johannes
2011-01-01
In this essay, Johannes Giesinger comments on the current philosophical debate on educational justice. He observes that while authors like Elizabeth Anderson and Debra Satz develop a so-called adequacy view of educational justice, Harry Brighouse and Adam Swift defend an egalitarian principle. Giesinger focuses his analysis on the main objection…
Targets and Witnesses: Middle School Students' Sexual Harassment Experiences
ERIC Educational Resources Information Center
Lichty, Lauren F.; Campbell, Rebecca
2012-01-01
School-based peer-to-peer sexual harassment (SH) emerged as an issue of concern in the early 1990s. As a developing field, this literature has several notable gaps. The current study extends previous research by, (a) exploring the understudied experiences of middle school students, (b) assessing students' experiences witnessing SH, and (c)…
ERIC Educational Resources Information Center
Campbell, Malcolm B.
This paper identifies issues currently arising in efforts to coordinate public policy concerning competing sectors of postsecondary education in the Organisation for Economic Cooperation and Development Countries (OECD). It is presented as a result of the OECD's advisement that these industrialized countries need to further strengthen education…
ERIC Educational Resources Information Center
Barnes, R. H.
1972-01-01
Emphasizes that from a practical point of view, it is important that studies with malnourished children emphasize the interactions between nutrition and environment rather than attempt complex, costly experiments which hopefully will assess the contribution of each of the components alone. (Author/JM)
The presence of human enteric viruses in drinking water is of public health concern. It is therefore important to be able to reliably detect these viruses in contaminating water sources. Cell culture methods are time consuming and also not all enteric viruses can currently be p...
ERIC Educational Resources Information Center
Gollin, George D.
2009-01-01
The global demand for higher education currently exceeds the world's existing university capacity. This shortfall is likely to persist for the foreseeable future, raising concerns that frustrated students might choose to purchase fraudulent credentials from counterfeiters or diploma mills. International efforts to encourage the development of…
Educational Equity Research in the Mainland of China: A Historical Perspective
ERIC Educational Resources Information Center
Zhang, Hongzhi
2016-01-01
Since the establishment of the People's Republic of China in 1949, there have been various discussions concerning educational equity in the different stages of education development. This paper focuses on the history and current situation of educational equity research in China. It examines the changes in the discourse on Chinese educational…
Saving Ohio's Historic Neighborhood Schools: A Primer for School Preservation Advocates.
ERIC Educational Resources Information Center
National Trust for Historic Preservation, Washington, DC.
This publication was developed to assist concerned citizens faced with the loss of their neighborhood schools. It recounts a brief history of school reform in Ohio, leading to the current crisis, and suggests strategies advocates for the preservation of their neighborhood schools can use to save their neighborhood assets. Broad issues addressed…
Integrating forest products with ecosystem services: a global perspective
Robert L. Deal; Rachel White
2012-01-01
Around the world forests provide a broad range of vital ecosystem services. Sustainable forest management and forest products play an important role in global carbon management, but one of the major forestry concerns worldwide is reducing the loss of forestland from development. Currently, deforestation accounts for approximately 20% of total greenhouse gas emissions....
Eating and Scraping Away at Practice with Two-Year-Olds
ERIC Educational Resources Information Center
Barron, Ian; Taylor, Lisa
2017-01-01
This paper examines how early childhood policy initiatives in the United Kingdom and internationally currently reflect neoliberal concerns with school readiness in the development of human capital and what diverse theoretical perspectives might offer. The focus is a project involving a group of early childhood academics from one university and a…
Sidelines and Separate Spaces: Making Education Anti-Racist for Students of Color
ERIC Educational Resources Information Center
Blackwell, Deanna M.
2010-01-01
The way in which anti-racist education is currently conceptualized and practiced holds very few benefits for students of color. By using whiteness theory and the politics of identity and difference, many educators have developed pedagogical interventions that are concerned with bringing white students into a consciousness about racism and white…
Reappraisal of Social Network Research in Educational Contexts.
ERIC Educational Resources Information Center
Scherer, Jacqueline
Three network studies in education are reviewed in order to assess the current "state of the art." New directions for developing social network analysis (SNA) in education, based upon experiences from a study of school-community relations in Pontiac, Michigan, are suggested. One concern for the future of SNA stems from the elevation of…
The State as a Work of Art: Statecraft for the 21st Century.
ERIC Educational Resources Information Center
Caldwell, Lynton K.
1996-01-01
Maintains that in the future the state will have to move beyond the politics of particular advantage (individual and group rights) to politics serving the general advantage (environmental concerns, economic development). Argues that current politics are dangerously outmoded in everything from their theoretical assumptions to data collecting. (MJP)
Alternative Conceptions Concerning the Earth's Interior Exhibited by Honduran Students
ERIC Educational Resources Information Center
Capps, Daniel K.; McAllister, Meredith; Boone, William J.
2013-01-01
Although multiple studies of misconceptions in Earth science have been completed using samples of North American and European students and teachers, little research has been conducted on alternative Earth science conceptions in developing countries. The current study was conducted in 5th- and 6th-grade classrooms in eastern Honduras, Central…
Resilience and Learning: A Conspectus for Environmental Education
ERIC Educational Resources Information Center
Lundholm, Cecilia; Plummer, Ryan
2010-01-01
There has been an increasing interest in how environmental education contributes to sustainability dating from the 1977 UNESCO conference in Tbilisi to the current Decade of Education for Sustainable Development, which in 2009, reached mid term. There is also a growing interest and concern in the complexity, uncertainty and changing nature of…
ERIC Educational Resources Information Center
Bilsland, Christine; Nagy, Helga; Smith, Phil
2014-01-01
Currently, there is little research into how Western universities can establish and implement effective WIL (Work Integrated Learning) in their offshore campuses. Given global concern with university graduates' general work-readiness, combined with a need for foreign universities to deliver relevant outcomes to its offshore students, greater…
ERIC Educational Resources Information Center
Benzie, Helen Joy
2010-01-01
The current concern about low levels of English proficiency among international students who graduate from degree courses--that students' English language skills are not being developed during their higher education experience--reflects negatively on the quality of Australian higher education and its graduates. More careful selection of students…
ERIC Educational Resources Information Center
Jiang, Hui; Davis, Dawn
2017-01-01
Let's Know! is a language-focused curriculum supplement developed through the Institute of Education Sciences' Reading for Understanding initiative aimed at supporting prekindergarten through grade 3 students' listening and reading comprehension. The current study reports results concerning the impacts of 2 instantiations of Let's Know! on…
Occasional Papers in Open and Distance Learning, Number 13.
ERIC Educational Resources Information Center
Donnan, Peter, Ed.
Each of the four papers in this collection is concerned with open learning in one form or another. "Open Learning: Some Current Perspectives" (Ian Barnard) addresses the topic of open learning in general, commenting on contemporary views and developments, and defining the term as a collective for approaches and practices that focus on…
Grammar and Good Taste: Reforming the American Language.
ERIC Educational Resources Information Center
Baron, Dennis E.
Tracing both current concern for correctness in speech and writing and continued suspicion of formal language regulation, this book explores the history of American language reform and failure. The first three chapters examine early attitudes toward the English language in the New World, and the development of the concept of Federal English in…
Child Care Subsidies and Child Development
ERIC Educational Resources Information Center
Herbst, Chris M.; Tekin, Erdal
2010-01-01
Child care subsidies are an important part of federal and state efforts to move welfare recipients into employment. One of the criticisms of the current subsidy system, however, is that it overemphasizes work and does little to encourage parents to purchase high-quality child care. Consequently, there are reasons to be concerned about the…
Developing an Instrument to Measure Bias in CME
ERIC Educational Resources Information Center
Takhar, Jatinder; Dixon, Dave; Donahue, Jill; Marlow, Bernard; Campbell, Craig; Silver, Ivan; Eadie, Jason; Monette, Celine; Rohan, Ivan; Sriharan, Abi; Raymond, Kathryn; Macnab, Jennifer
2007-01-01
Introduction: The pharmaceutical industry, by funding over 60% of programs in the United States and Canada, plays a major role in continuing medical education (CME), but there are concerns about bias in such CME programs. Bias is difficult to define, and currently no tool is available to measure it. Methods: Representatives from industry and…
Navigating the Health Care System: An Adolescent Health Literacy Unit for High Schools
ERIC Educational Resources Information Center
Hughes, Denise; Maiden, Kristin
2018-01-01
Background: Currently, no intervention concerning transition of health care responsibilities from parents to teens exists for adolescents in the general population. The purpose of this intervention was to evaluate teacher satisfaction and student knowledge gain of a health unit developed for adolescents on becoming their own health care advocates.…
Probing High School Physics Students' Views and Concerns about Learning Activities
ERIC Educational Resources Information Center
Langley, Dorothy; Eylon, Bat-Sheva
2006-01-01
The current study is framed within an ongoing effort of probing students' attitudes and expectations about knowing and learning physics, which has driven several investigations during the past decade. The questionnaire we developed focuses on physics students' views regarding a variety of specific learning activities, which are presented by title…
Minnesota Education Yearbook, 2000: The Status of Pre-K-12 Education in Minnesota.
ERIC Educational Resources Information Center
Minnesota Univ., Minneapolis. Coll. of Education and Human Development.
The Office of Educational Accountability has compiled and analyzed indicators of progress in developing a statewide accountability system in Minnesota. This report focuses on the state as a whole, not on specific schools or districts. Chapter 1 is an introduction to Minnesota's accountability history and current concerns. Chapter 2 examines…
Toward the Thinking Curriculum: Current Cognitive Research. 1989 ASCD Yearbook.
ERIC Educational Resources Information Center
Resnick, Lauren B., Ed.; Klopfer, Leopold E., Ed.
A project of the Center for the Study of Learning at the University of Pittsburgh, this yearbook combines the two major trends/concerns impacting the future of educational development for the next decade: knowledge and thinking. The yearbook comprises the following chapters: (1) "Toward the Thinking Curriculum: An Overview" (Lauren B.…
Gender Equity: Still Knocking at the Classroom Door.
ERIC Educational Resources Information Center
Sadker, David
2000-01-01
Examines the salient and current research on gender progress and problems in U.S. schools, discussing some of the disturbing cultural developments that have distorted and politicized educational equity. Focuses on the top 10 gender bias problems found in the schools and discusses the effect of social resistance to feminism, female concerns, and…
Applying an Appreciative Inquiry Process to a Course Evaluation in Higher Education
ERIC Educational Resources Information Center
Kung, Susie; Giles, David; Hagan, Bill
2013-01-01
While appreciative inquiry (AI) has its origins in organizational development, this article considers the application of AI within a course evaluation in higher education. An AI process was deemed appropriate given its concern for peak performance or life-centric experiences. Former students of a particular course, along with current students,…
Understanding and (Dis)trusting Food Assurance Schemes: Consumer Confidence and the "Knowledge Fix"
ERIC Educational Resources Information Center
Eden, Sally; Bear, Christopher; Walker, Gordon
2008-01-01
This paper uses evidence from focus groups with consumers in England to consider how consumers understand and evaluate a range of proxies or intermediary organisations that offer assurance about food and consumer products, particularly voluntary certification schemes. This addresses the current concern in developed economies about providing…
Safe Schools: Unified Emergency Contingency Plan for Schools.
ERIC Educational Resources Information Center
Illinois State Police, Springfield.
This contingency plan is intended to stimulate emergency planning and provide an organizational tool for Illinois schools to use in the development of individual emergency plans. It may accommodate and complement a school's current contingency plan and will allow for the inclusion of additional material concerning school safety. It is intended as…
Designing and Developing a Work Experience Component for a Vocational Education Curriculum.
ERIC Educational Resources Information Center
Santos, Otto, Jr.; Olinzock, Anthony
A work experience component for vocational educator teacher education based on demonstrated competence is proposed. Its basis is research concerning vocational education; sociometric conditions and needs; analyses of the past, present, and future of vocational education; and the current state of the art relative to curriculum systems. This…
17 CFR 232.313 - Identification of investment company type and series and/or class (or contract).
Code of Federal Regulations, 2013 CFR
2013-04-01
... company type and series and/or class (or contract). 232.313 Section 232.313 Commodity and Securities... series and/or class (or contract). (a) Registered investment companies and business development companies... keep current, information concerning their existing and new series and/or classes (or contracts, in the...
17 CFR 232.313 - Identification of investment company type and series and/or class (or contract).
Code of Federal Regulations, 2010 CFR
2010-04-01
... company type and series and/or class (or contract). 232.313 Section 232.313 Commodity and Securities... series and/or class (or contract). (a) Registered investment companies and business development companies... keep current, information concerning their existing and new series and/or classes (or contracts, in the...
Gender, Assessment and Students' Literacy Learning: Implications for Formative Assessment
ERIC Educational Resources Information Center
Murphy, Patricia; Ivinson, Gabrielle
2005-01-01
Formative assessment is intended to develop students' capacity to learn and increase the effectiveness of teaching. However, the extent to which formative assessment can meet these aims depends on the relationship between its conception and current conceptions of learning. In recent years concern about sex group differences in achievement has led…
A Bright Promise but a Dim Future. Researchers Examine Potential of Educational Technology.
ERIC Educational Resources Information Center
Pitts, Marcella R., Ed.
Concerns about the current educational technology movement are discussed in these four papers which were presented during a seminar of 20 representatives from 10 Council for Educational Development and Research (CEDaR) member institutions. The first by Marcella Pitts and E. Joseph Schneider provides an overview of the educational technology…
Management of Learning. New Dimensions in Higher Education. Number 5.
ERIC Educational Resources Information Center
Duryea, E. D.; Hatch, Winslow R.
Areas of academic administration with which current thinking is concerned are indicated, and a conceptual scheme reflecting these areas and pointing to directions for future studies is suggested. Published and unpublished work that develops new insights into the theory, process, and operations of college and university administration is reviewed.…
Pestereva, N M; Khechumyan, A F; Udovenko, I L; Bekhterev, V N
2016-01-01
The present review summarizes the data published in the domestic and foreign literature concerning the history of climatic therapy, the current concepts of the mechanisms of action of the climatic and weather factors on the human body, the modern therapeutic modalities and technologies for health promotion. We consider not only the achievements but also the problems arising from insufficient knowledge of the impacts of current climate and extreme weather conditions on the state of human health and some disputable issues of the new methods and technologies of climatic therapy. the promising areas of further research and developments pertaining to climatic therapy as practiced under conditions of the Black Sea coast resorts.
Brown, Matt A; Bishnoi, Ram J; Dholakia, Sara; Velligan, Dawn I
2016-01-20
Recent failures to detect efficacy in clinical trials investigating pharmacological treatments for schizophrenia raise concerns regarding the potential contribution of methodological shortcomings to this research. This review provides an examination of two key methodological issues currently suspected of playing a role in hampering schizophrenia drug development; 1) limitations on the translational utility of preclinical development models, and 2) methodological challenges posed by increased placebo effects. Recommendations for strategies to address these methodological issues are addressed.
Bharucha, Tehmina; Ming, Damien; Breuer, Judith
2017-08-03
HZ/Su, branded as 'Shingrix', is one of the newest vaccines to be submitted for multi-national regulatory approval. It is targeted to prevent shingles, a global concern with aging populations. A live attenuated vaccine for shingles has been available for over a decade, however it is contraindicated in specific subgroups of people, and there are added concerns regarding long-term immunogenicity. HZ/Su is the first subunit vaccine developed to protect against shingles. This paper provides a critical appraisal of current evidence regarding HZ/Su.
Vaccination of Ferrets for Rabies and Distemper.
Wade, Laura L
2018-01-01
Companion ferrets need to be vaccinated against 2 viral diseases that cause neurologic illness: canine distemper and rabies. Although not common in ferrets, both viruses are fatal in ferrets and rabies virus is also fatal in humans. In this article, we provide a basic review of the 2 diseases, highlighting key neurologic concerns. We also review and update current vaccine concerns from a practitioner's perspective, including available vaccines, vaccine schedule recommendations, vaccine reactions, and risk assessment. Last, we mention the ferret and its use in cutting-edge vaccine development. Copyright © 2017 Elsevier Inc. All rights reserved.
Heikkilä, Teppo Juhani; Hyppölä, Harri; Aine, Tiina; Halila, Hannu; Vänskä, Jukka; Kujala, Santero; Virjo, Irma; Mattila, Kari
2014-02-01
Though there are a number of studies investigating the career choices of physicians, there are only few concerning doctors' choices of workplace. A random sample (N=7758) of physicians licensed in Finland during the years 1977-2006 was surveyed. Respondents were asked: "To what extent did the following motives affect your choice of your current workplace?" Respondents were grouped based on several background variables. The groups were used as independent variables in univariate analysis of covariance (ANCOVA). The factors Good workplace, Career and professional development, Non-work related issues, Personal contacts and Salary were formed and used as dependent variables. There were significant differences between groups of physicians, especially in terms of gender, working sector and specialties. The association of Good workplace, Career and professional development, and Non-work related issues with the choice of a workplace significantly decreased with age. Female physicians were more concerned with Career and professional development and Non-work related issues. Since more females are entering the medical profession and there is an ongoing change of generations, health care organizations and policy makers need to develop a new philosophy in order to attract physicians. This will need to include more human-centric management and leadership, better possibilities for continuous professional development, and more personalized working arrangements depending on physician's personal motives. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.
Werner, Angela K; Vink, Sue; Watt, Kerrianne; Jagals, Paul
2015-02-01
Rapid global expansion of unconventional natural gas development (UNGD) raises environmental health concerns. Many studies present information on these concerns, yet the strength of epidemiological evidence remains tenuous. This paper is a review of the strength of evidence in scientific reporting of environmental hazards from UNGD activities associated with adverse human health outcomes. Studies were drawn from peer-reviewed and grey literature following a systematic search. Five databases were searched for studies published from January 1995 through March 2014 using key search terms relevant to environmental health. Studies were screened, ranked and then reviewed according to the strength of the evidence presented on adverse environmental health outcomes associated with UNGD. The initial searches yielded >1000 studies, but this was reduced to 109 relevant studies after the ranking process. Only seven studies were considered highly relevant based on strength of evidence. Articles spanned several relevant topics, but most focussed on impacts on typical environmental media, such as water and air, with much of the health impacts inferred rather than evidenced. Additionally, the majority of studies focussed on short-term, rather than long-term, health impacts, which is expected considering the timeframe of UNGD; therefore, very few studies examined health outcomes with longer latencies such as cancer or developmental outcomes. Current scientific evidence for UNGD that demonstrates associations between adverse health outcomes directly with environmental health hazards resulting from UNGD activities generally lacks methodological rigour. Importantly, however, there is also no evidence to rule out such health impacts. While the current evidence in the scientific research reporting leaves questions unanswered about the actual environmental health impacts, public health concerns remain intense. This is a clear gap in the scientific knowledge that requires urgent attention. Copyright © 2014. Published by Elsevier B.V.
Description of research interests and current work related to automating software design
NASA Technical Reports Server (NTRS)
Kaindl, Hermann
1992-01-01
Enclosed is a list of selected and recent publications. Most of these publications concern applied research in the areas of software engineering and human-computer interaction. It is felt that domain-specific knowledge plays a major role in software development. Additionally, it is believed that improvements in the general software development process (e.g., object-oriented approaches) will have to be combined with the use of large domain-specific knowledge bases.
The development of language and literacy: evaluating the stereotypes.
Goodman, Judith C; Wagovich, Stacy A
2009-01-01
People hold many stereotypes about the development of language and reading. We review current data concerning three stereotypes: (1) Girls learn language faster than boys; (2) Biological factors determine the time course of language acquisition; and (3) Dyslexia is a visual problem involving the reversal of letters. In each case, recent data leads to a different picture of the acquisition of language and literacy and deepens our understanding of the processes involved.
Shen, Xiaoyun; Orson, Frank M.; Kosten, Thomas R.
2012-01-01
Current medications for drug abuse have had only limited success. Anti-addiction vaccines to elicit antibodies that block the pharmacological effects of drugs have great potential for treating drug abuse. We review the status for two vaccines that are undergoing clinical trials (cocaine and nicotine) and two that are still in pre-clinical development (methamphetamine and heroin). We also outline the challenges and ethical concerns for anti-addiction vaccine development and their use as future therapeutics. PMID:22130115
3-D Numerical Simulations of Biofilm Dynamics with Quorum Sensing in a Flow Cell
2014-01-01
resistant mutants [?]. Inspired by experimental findings, researchers have come up with some mathematical models to study biofilm formation and function...develop a full 3D mathematical model to study how quorum sensing regulates biofilm formation and development as well as the pros and cons of quorum...have given an overview of current advances in mathematical modeling of biofilms. Concerning coupling biofilm growth with quorum sensing features
ERIC Educational Resources Information Center
Osman, Omer M.
Current and future issues concerning Arab higher education are discussed, along with the structure and growth of the economy and the development of general education. Economic data for 21 Arab countries are provided for 1979 that cover the per capita national income; annual rate of growth in national income; and the share of growth by the labor…
Alternative Future Scenarios: Development of a Modeling Information System
2003-04-22
the Nation’s population by the year 2020. Riverside County is of particular concern to Joshua Tree National Park because of the rapid rate of...not display a currently valid OMB control number. 1. REPORT DATE 22 APR 2003 2. REPORT TYPE 3. DATES COVERED 00-00-2003 to 00-00-2003 4. TITLE...4 DoD cannot afford to ignore the hierarchical effects of development pressures........................ 5 TYPES OF MODELS/MODEL ENVIRONMENT
China’s Currency: Economic Issues and Options for U.S. Trade Policy
2007-07-15
a policy that is practiced by a variety of developing countries . Chinese officials have expressed concern that abandoning the current currency...has been proven to be unreliable in reality: prices are consistently lower in developing countries than industrialized countries . Some economists have...not caused by the exchange rate policy of one country , but rather the shortfall between U.S. saving and investment. That being said, there are a
Zhao, Haichao; Qiao, Lei; Fan, Dongqiong; Zhang, Shuyue; Turel, Ofir; Li, Yonghui; Li, Jun; Xue, Gui; Chen, Antao; He, Qinghua
2017-01-01
Transcranial direct current stimulation (tDCS) is a widely-used tool to induce neuroplasticity and modulate cortical function by applying weak direct current over the scalp. In this review, we first introduce the underlying mechanism of action, the brief history from discovery to clinical scientific research, electrode positioning and montages, and parameter setup of tDCS. Then, we review tDCS application in clinical samples including people with drug addiction, major depression disorder, Alzheimer's disease, as well as in children. This review covers the typical characteristics and the underlying neural mechanisms of tDCS treatment in such studies. This is followed by a discussion of safety, especially when the current intensity is increased or the stimulation duration is prolonged. Given such concerns, we provide detailed suggestions regarding safety procedures for tDCS operation. Lastly, future research directions are discussed. They include foci on the development of multi-tech combination with tDCS such as with TMS and fMRI; long-term behavioral and morphological changes; possible applications in other research domains, and more animal research to deepen the understanding of the biological and physiological mechanisms of tDCS stimulation. PMID:28539894
Moving toward a paradigm shift in the regulatory requirements for pediatric medicines.
Chin, William Wei Lim; Joos, Angelika
2016-12-01
Over the past two decades, there has been growing concern over the lack of proper medication for children. This review attempts to evaluate the current progress of EU Pediatric Regulation made since 2007. The lack of properly evaluated pediatric medication has for long been a source of concern in the European Union. The drugs that were used in the past were often not properly evaluated, and dosage was arbitrarily calculated. Therefore, it was necessary to establish the Pediatric Regulation (EC no. 1901/2006) in the EU which would mandate research for pediatric drugs. Current legislations in place not only require mandatory research by pharma industry but also have guidelines to direct the quality of pediatric research performed. The main aim of this regulation was to advance high-quality research and development of pediatric drugs, thereby increasing the availability of safe and effective drugs for children. It also aimed to improve the information available on existing pediatric drugs. It has been 9 years since the pediatric regulation was framed. The pharma industry now sees pediatric research as an integral process of development. Drug companies which develop plans for a new drug, new form of drug, new indication, or new route of administration for adults are obliged to integrate in their development plan similar research for pediatric populations as well. It is hoped that the implementation of the current legislation will be reflected better in the future by the marketing of better and safer drugs for the pediatric population. The upcoming assessment to the European Commission in 2017 will further inform us on the impact after 10 years implementation of the legislation. What is Known: • The lack of properly evaluated pediatric medication has for long been a source of concern in the European Union. • Therefore, it was necessary to establish the EU Pediatric Regulation which would mandate research for pediatric drugs. What is New: • It has been 9 years since the pediatric regulation was framed, and the teething problems are slowly being overcome and the regulation is being used with increasing confidence. • As the Regulation is due for revision in 2017, this paper gives a current perspective on the impact of the regulation on availability and access to medicine for children.
Tobacco and the developing world.
Mackay, J; Crofton, J
1996-01-01
Tobacco consumption is increasing in developing countries, which will bear the brunt of the tobacco epidemic in the 21st century. If current smoking patterns continue, 7 of the world's 10 million annual deaths from tobacco in 2025 will occur in developing countries. Compared with developed countries, more men and fewer women currently smoke in developing countries, but smoking among girls and women is increasing. While indigenous tobacco production and consumption remain a major problem, of particular concern is the penetration by the transnational tobacco companies, bringing with them denial of the health evidence, sophisticated advertising and promotion, threats of trade sanctions based on tobacco trade, and opposition to tobacco control measures, in particular promotional bans and tobacco tax policy. Developing countries must urgently devise and implement national tobacco control policies, but many governments have little experience in the new noncommunicable disease epidemic or in countering the transnational tobacco companies.
Gonzales, Cara B.; Young, Veronica; Ketchum, Norma S.; Bone, Jamie; Oates, Thomas W.; Mungia, Rahma
2015-01-01
Bisphosphonate-induced osteonecrosis of the jaw (BONJ) represents a growing concern for dentists and patients, in that it may alter clinical care. This study assesses the knowledge and perceptions of practicing dentists in relation to the risk of BONJ and how their knowledge and perceptions influence their decisions when developing treatment plans. For this study, a sample of dentists (n = 93) in South Texas completed a 38-item survey about BONJ knowledge and perception and their current clinical practices for patients undergoing bisphosphonate therapy. Knowledge score groupings reflected differences between low-knowledge and high-knowledge dentists in terms of their behavior concerning medical history, alternative treatments offered, and routine blood testing for patients on bisphosphonate therapy. PMID:25734289
Challenges in reducing dengue burden; diagnostics, control measures and vaccines.
Lam, Sai Kit
2013-09-01
Dengue is a major public health concern worldwide, with the number of infections increasing globally. The illness imposes the greatest economic and human burden on developing countries that have limited resources to deal with the scale of the problem. No cure for dengue exists; treatment is limited to rehydration therapy, and with vector control strategies proving to be relatively ineffective, a vaccine is an urgent priority. Despite the numerous challenges encountered in the development of a dengue vaccine, several vaccine candidates have shown promise in clinical development and it is believed that a vaccination program would be at least as cost-effective as current vector control programs. The lead candidate vaccine is a tetravalent, live attenuated, recombinant vaccine, which is currently in Phase III clinical trials. Vaccine introduction is a complex process that requires consideration and is discussed here. This review discusses the epidemiology, burden and pathogenesis of dengue, as well as the vaccine candidates currently in clinical development.
Biorefineries for the production of top building block chemicals and their derivatives.
Choi, Sol; Song, Chan Woo; Shin, Jae Ho; Lee, Sang Yup
2015-03-01
Due to the growing concerns on the climate change and sustainability on petrochemical resources, DOE selected and announced the bio-based top 12 building blocks and discussed the needs for developing biorefinery technologies to replace the current petroleum based industry in 2004. Over the last 10 years after its announcement, many studies have been performed for the development of efficient technologies for the bio-based production of these chemicals and derivatives. Now, ten chemicals among these top 12 chemicals, excluding the l-aspartic acid and 3-hydroxybutyrolactone, have already been commercialized or are close to commercialization. In this paper, we review the current status of biorefinery development for the production of these platform chemicals and their derivatives. In addition, current technological advances on industrial strain development for the production of platform chemicals using micro-organisms will be covered in detail with case studies on succinic acid and 3-hydroxypropionic acid as examples. Copyright © 2015 International Metabolic Engineering Society. Published by Elsevier Inc. All rights reserved.
The Tension Between Data Sharing and the Protection of Privacy in Genomics Research
Kaye, Jane
2014-01-01
Next-generation sequencing and global data sharing challenge many of the governance mechanisms currently in place to protect the privacy of research participants. These challenges will make it more difficult to guarantee anonymity for participants, provide information to satisfy the requirements of informed consent, and ensure complete withdrawal from research when requested. To move forward, we need to improve the current governance systems for research so that they are responsive to individual privacy concerns but can also be effective at a global level. We need to develop a system of e-governance that can complement existing governance systems but that places greater reliance on the use of technology to ensure compliance with ethical and legal requirements. These new governance structures must be able to address the concerns of research participants while at the same time ensuring effective data sharing that promotes public trust in genomics research. PMID:22404490
The tension between data sharing and the protection of privacy in genomics research.
Kaye, Jane
2012-01-01
Next-generation sequencing and global data sharing challenge many of the governance mechanisms currently in place to protect the privacy of research participants. These challenges will make it more difficult to guarantee anonymity for participants, provide information to satisfy the requirements of informed consent, and ensure complete withdrawal from research when requested. To move forward, we need to improve the current governance systems for research so that they are responsive to individual privacy concerns but can also be effective at a global level. We need to develop a system of e-governance that can complement existing governance systems but that places greater reliance on the use of technology to ensure compliance with ethical and legal requirements. These new governance structures must be able to address the concerns of research participants while at the same time ensuring effective data sharing that promotes public trust in genomics research.
Mixtures and their risk assessment in toxicology.
Mumtaz, Moiz M; Hansen, Hugh; Pohl, Hana R
2011-01-01
For communities generally and for persons living in the vicinity of waste sites specifically, potential exposures to chemical mixtures are genuine concerns. Such concerns often arise from perceptions of a site's higher than anticipated toxicity due to synergistic interactions among chemicals. This chapter outlines some historical approaches to mixtures risk assessment. It also outlines ATSDR's current approach to toxicity risk assessment. The ATSDR's joint toxicity assessment guidance for chemical mixtures addresses interactions among components of chemical mixtures. The guidance recommends a series of steps that include simple calculations for a systematic analysis of data leading to conclusions regarding any hazards chemical mixtures might pose. These conclusions can, in turn, lead to recommendations such as targeted research to fill data gaps, development of new methods using current science, and health education to raise awareness of residents and health care providers. The chapter also provides examples of future trends in chemical mixtures assessment.
"At this point now": older workers' reflections on their current employment experiences.
Noonan, Anne E
2005-01-01
Despite the frequently referenced graying of the U.S. workforce, we know relatively little about the work-related concerns and experiences of older workers--those aged 55+. This qualitative study addresses that gap by examining the current employment situations of a purposive sample of 37 older workers. Thematic content analysis revealed a vast diversity in the concerns and experiences of contemporary older workers, with participants being actively involved in all of the traditional stages of work-life development. Findings suggest a deepened or more nuanced view of the principal meanings of work--in particular, identity and social interaction--and highlight several negative aspects of later-life employment such as pension insecurity, unemployment, age discrimination, not having found one's "niche," and chronic interpersonal difficulties with co-workers. Findings are discussed against the backdrop of a rapidly changing workplace and dramatically shifting work-retirement trajectories in which job stability and predictable retirement are less common.
Psychosocial Concerns in the Postoperative Oncology Patient.
Ercolano, Elizabeth
2017-02-01
To describe psychosocial concerns associated with the postoperative cancer patient and to discuss current psychosocial evidence-based approaches to manage these psychosocial concerns. Published peer-reviewed literature. The postoperative phase of cancer care may be associated with a range of overlapping acute and chronic psychosocial concerns related to the surgery itself, the cancer diagnosis, and the need for ongoing cancer treatments. The postoperative period of cancer care represents an essential time to detect unmet psychosocial concerns and begin timely interventions for these concerns. Nurses are in a key position to detect, triage, refer, or manage psychosocial concerns in the postoperative patient with cancer. Current psychosocial evidence-based approaches may be used by surgical oncology nurses or other nurses who care for cancer patients during postoperative recovery. Copyright © 2016. Published by Elsevier Inc.
Chan, Sarah
2017-10-01
Probably the most serious problem facing the field of regenerative medicine today is the challenge of effective translation and development of viable stem cell-based therapies. Particular concerns have been raised over the growing market in unproven cell therapies. In this article, I explore recent developments in the stem cell therapy landscape and argue that while the sale of unproven therapies undoubtedly poses ethical concerns, it must be understood as part of a larger problem at the interface between biomedicine, healthcare, publics, policy and the market. Addressing this will require a broader perspective incorporating the shifting relationships between different stakeholder groups, the global politics of research and innovation, and the evolving role of publics and patients with respect to science.
Patterson, Steven L; Dancy, Blair C R; Ippolito, Danielle L; Stallings, Jonathan D
2017-11-01
: This paper presents environmental health risks which are prevalent in dense urban environments.We review the current literature and recommendations proposed by environmental medicine experts in a 2-day symposium sponsored by the Department of Defense and supported by the Johns Hopkins University Applied Physics Laboratory.Key hazards in the dense urban operational environment include toxic industrial chemicals and materials, water pollution and sewage, and air pollution. Four critical gaps in environmental medicine were identified: prioritizing chemical and environmental concerns, developing mobile decision aids, personalized health assessments, and better real-time health biomonitoring.As populations continue to concentrate in cities, civilian and military leaders will need to meet emerging environmental health concerns by developing and delivering adequate technology and policy solutions.
Chan, Sarah
2017-01-01
Probably the most serious problem facing the field of regenerative medicine today is the challenge of effective translation and development of viable stem cell-based therapies. Particular concerns have been raised over the growing market in unproven cell therapies. In this article, I explore recent developments in the stem cell therapy landscape and argue that while the sale of unproven therapies undoubtedly poses ethical concerns, it must be understood as part of a larger problem at the interface between biomedicine, healthcare, publics, policy and the market. Addressing this will require a broader perspective incorporating the shifting relationships between different stakeholder groups, the global politics of research and innovation, and the evolving role of publics and patients with respect to science. PMID:29119870
DOE Office of Scientific and Technical Information (OSTI.GOV)
Darby, John L.
2011-05-01
As the nuclear weapon stockpile ages, there is increased concern about common degradation ultimately leading to common cause failure of multiple weapons that could significantly impact reliability or safety. Current acceptable limits for the reliability and safety of a weapon are based on upper limits on the probability of failure of an individual item, assuming that failures among items are independent. We expanded the current acceptable limits to apply to situations with common cause failure. Then, we developed a simple screening process to quickly assess the importance of observed common degradation for both reliability and safety to determine if furthermore » action is necessary. The screening process conservatively assumes that common degradation is common cause failure. For a population with between 100 and 5000 items we applied the screening process and conclude the following. In general, for a reliability requirement specified in the Military Characteristics (MCs) for a specific weapon system, common degradation is of concern if more than 100(1-x)% of the weapons are susceptible to common degradation, where x is the required reliability expressed as a fraction. Common degradation is of concern for the safety of a weapon subsystem if more than 0.1% of the population is susceptible to common degradation. Common degradation is of concern for the safety of a weapon component or overall weapon system if two or more components/weapons in the population are susceptible to degradation. Finally, we developed a technique for detailed evaluation of common degradation leading to common cause failure for situations that are determined to be of concern using the screening process. The detailed evaluation requires that best estimates of common cause and independent failure probabilities be produced. Using these techniques, observed common degradation can be evaluated for effects on reliability and safety.« less
Agriculture for improved nutrition: the current research landscape.
Turner, Rachel; Hawkes, Corinna; Jeff, Waage; Ferguson, Elaine; Haseen, Farhana; Homans, Hilary; Hussein, Julia; Johnston, Deborah; Marais, Debbi; McNeill, Geraldine; Shankar, Bhavani
2013-12-01
Concern about food security and its effect on persistent undernutrition has increased interest in how agriculture could be used to improve nutritional outcomes in developing countries. Yet the evidence base for the impact of agricultural interventions targeted at improved nutrition is currently poor. To map the extent and nature of current and planned research on agriculture for improved nutrition in order to identify gaps where more research might be useful. The research, which was conducted from April to August 2012, involved developing a conceptual framework linking agriculture and nutrition, identifying relevant research projects and programs, devising and populating a "template" with details of the research projects in relation to the conceptual framework, classifying the projects, and conducting a gap analysis. The study identified a large number of research projects covering a broad range of themes and topics. There was a strong geographic focus on sub-Saharan Africa, and many studies were explicitly concerned with nutritional impacts on women and children. Although the study revealed a diverse and growing body of research, it also identified research gaps. Few projects consider the entire evidence chain linking agricultural input or practice to nutritional outcomes. There is comparatively little current research on indirect effects of agriculture on nutrition, or the effect of policies or governance, rather than technical interventions. Most research is focused on undernutrition and small farmer households, and few studies target consumers generally, urban populations, or nutrition-related non-communicable diseases. There is very little work on the cost-effectiveness of agricultural interventions. On the basis of these findings, we make suggestions for research investment and for broader engagement of researchers and disciplines in developing approaches to design and evaluate agricultural programs for improved nutrition.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Not Available
1979-08-01
A comprehensive assessment of the biofuel potential of Peru is presented. Topics discussed cover current biofuel utilization practices; evaluation of Peruvian biomass productivity; identification of Peruvian agricultural and forestry resources; assessment of resource development and management concerns; identification of market considerations; description of biofuel technological options; and regional identification of biofuel technology applications. The discussion of current biofuel utilization centers on a qualitative description of the main conversion approaches now being practiced in Peru. Biomass productivity is evaluated in the context of the terrain, soil, and climatic conditions found in Peru. A quantitative description of the energy potential that couldmore » be realized from agricultural and forestry resources of Peru follows. A regional picture is given for the production of agricultural residues and forest resources that could potentially supply energy. The assessment of resource development and management concerns focuses on harvesting, reforestation, training, and the environmental consequences of utilization of forest resources. Market factors assessed include: importation, internal market development, external market development, energy policy and pricing, and transportation. Ten biofuel technology options for Peru were identified: small- to medium-scale gasification, a wood waste inventory, stationary and mobile charcoal production systems, wood distillation, forest resource development and management, electrical cogeneration, anaerobic digestion technology, development of ethanol production capabilities, and agricultural strategies for fuel production.Based upon these biofuel options, nine applications were identified for the Costa Region, eight for the Sierra Region, and ten for the Selva Region.« less
Colquhoun, Amy; Aplin, Laura; Geary, Janis; Goodman, Karen J; Hatcher, Juanita
2012-05-08
Population health data are vital for the identification of public health problems and the development of public health strategies. Challenges arise when attempts are made to disseminate or access anonymised data that are deemed to be potentially identifiable. In these situations, there is debate about whether the protection of an individual's privacy outweighs potentially beneficial public health initiatives developed using potentially identifiable information. While these issues have an impact at planning and policy levels, they pose a particular dilemma when attempting to examine and address community concerns about a specific health problem. Research currently underway in northern Canadian communities on the frequency of Helicobacter pylori infection and associated diseases, such as stomach cancer, is used in this article to illustrate the challenges that data controls create on the ability of researchers and health officials to address community concerns. Barriers are faced by public health professionals and researchers when endeavouring to address community concerns; specifically, provincial cancer surveillance departments and community-driven participatory research groups face challenges related to data release or access that inhibit their ability to effectively address community enquiries. The resulting consequences include a limited ability to address misinformation or to alleviate concerns when dealing with health problems in small communities. The development of communication tools and building of trusting relationships are essential components of a successful investigation into community health concerns. It may also be important to consider that public wellbeing may outweigh the value of individual privacy in these situations. As such, a re-evaluation of data disclosure policies that are applicable in these circumstances should be considered.
ERIC Educational Resources Information Center
Collins, Helen
This workbook, which is intended as a practical guide for human resource managers, trainers, and others concerned with developing and implementing equal opportunities training programs in British workplaces, examines issues in and methods for equal opportunities training. The introduction gives an overview of current training trends and issues.…
ERIC Educational Resources Information Center
Delahunty, Thomas; Seery, Niall; Lynch, Raymond
2018-01-01
Currently, there is significant interest being directed towards the development of STEM education to meet economic and societal demands. While economic concerns can be a powerful driving force in advancing the STEM agenda, care must be taken that such economic imperative does not promote research approaches that overemphasize pragmatic application…
USDA-ARS?s Scientific Manuscript database
Fusarium Head Blight is a worldwide disease of small cereals grains such as wheat. The disease is food safety concern because it produces the metabolite, deoxynivalenol (DON), which is moderately toxic to humans and non-ruminant animals. The current study was implemented to develop more efficient me...
ERIC Educational Resources Information Center
Deagle, Elena; D'Amico, Miranda
2016-01-01
The current study is a qualitative analysis of the results of a literacy skills intervention with a group comprising of three individuals with Down syndrome and three individuals with other developmental disabilities. The intervention was developed to address the concern that individuals in this population are often only exposed to functional…
Reaching Boys: An International Study of Effective Teaching Practices
ERIC Educational Resources Information Center
Reichert, Michael; Hawley, Richard
2010-01-01
Despite a continuing stream of concern on the part of researchers, demographers, and cultural pundits about a crisis in boys' social development and schooling, surprisingly little attention has been paid to what is perhaps the richest pool of data: current, observable teaching practices that clearly work with boys. In schools of all types in all…
A Pilot Evaluation of an Art Therapy Program for Refugee Youth from Burma
ERIC Educational Resources Information Center
Kowitt, Sarah Dorothy; Emmerling, Dane; Gavarkavich, Diane; Mershon, Claire-Helene; Linton, Kristin; Rubesin, Hillary; Agnew-Brune, Christine; Eng, Eugenia
2016-01-01
Art therapy is a promising form of therapy to address mental health concerns for refugee youth. This article describes the development and implementation of a pilot evaluation of an art therapy program for refugee adolescents from Burma currently living in the United States. Evaluation activities were based on the Centers for Disease Control and…
ERIC Educational Resources Information Center
Hodgson, Devon Rachelle
2009-01-01
Researchers argue that a California Community College's capacity for improvement and reform, given the multitude of concerns and organizational barriers associated with education institutions will require transformation of current practices to influence organizational learning (O'Banion, 1997; Cohen, 1996). Extant literature has demonstrated the…
Extensive Writing in Foreign-Language Classrooms: A Blogging Approach
ERIC Educational Resources Information Center
Sun, Yu-Chih
2010-01-01
A weblog (blog or Web log) has recently become one of the most widely used Internet applications. The current study concerns developing a blog specifically designed for learners learning English as a foreign language. The study investigated the effects of extensive writing by comparing the writing performance in the first three and the last three…
ERIC Educational Resources Information Center
Evans, Roy
Emphasizing that for any known teratogen no safe dosage level exists, this case-illustrated review identifies the bases for current concern about the pollution of the environment, reflects on the promise and complexities of the emerging disciplines of behavioral toxicology and behavioral teratology, and describes existing evidence of teratogenic…
ERIC Educational Resources Information Center
Choi, Jung-Min
2010-01-01
The primary concern in current interaction design is focused on how to help users solve problems and achieve goals more easily and efficiently. While users' sufficient knowledge acquisition of operating a product or system is considered important, their acquisition of problem-solving knowledge in the task domain has largely been disregarded. As a…
Practical Implementation of Global Citizenship Education at the Slovak University of Agriculture
ERIC Educational Resources Information Center
Mravcová, Anna
2016-01-01
Global citizenship is still a relatively new concept concerned mainly with the growing prominence of global and development education issues. The importance of this phenomenon is increasing in the area of education, which must be able to respond to the interconnection and interdependency of the current world. There is an effort to support…
1982-05-01
insufficient need for a hard metric version of the ASME Boiler and Pressure Vessel Code and industry would not support the metric version. The Code Is not...aircraft industry is concerned with certification requirements in metric units. The inch-pound Boiler and Pressure Vessel Code is the current standard
Management of a river recreation resource: the Lower Kananaskis River--a case study
Kimberley Rae; Paul F.J. Eagles
2008-01-01
This study examined recreational use of the Lower Kananaskis River in Southwestern Alberta, Canada. Surveys and participant observations helped develop a better understanding of current use levels and interviews with key policy leaders explored management issues and concerns. Users suggested the need for improvements to river infrastructure both on and off the river....
Descending the Tower: Lessons Learned in a First Grade Classroom.
ERIC Educational Resources Information Center
Ford, Michael P.
In light of concerns that previous staff development projects did not truly capture life in the classroom, and that there may be a gap between one's previous elementary and current university teaching experiences, a teacher educator used a semester sabbatical to shadow six first-grade teachers in order to inform thinking and practice in teaching…
ERIC Educational Resources Information Center
Edwards, Nancy Joan
The development, current status, and future prospects of community colleges are examined in this study with special emphasis on finance and funding concerns. Introductory material outlines study objectives, methodology, and purposes; defines key terms; and emphasizes the importance of college planning. Chapter 1 presents a history of the community…
ERIC Educational Resources Information Center
McLachlan, Claire; Smith, Jessica; McLaughlin, Tara; Ali, Ajmol; Conlon, Cathryn; Mugridge, Owen; Foster, Sophie
2017-01-01
In order to support children's physical health and well-being in early childhood education programmes, it is important to understand how teacher practices concerned with physical activity and nutrition can be addressed effectively. Current evidence suggests that young children's opportunities for physical activity in early childhood are…
ERIC Educational Resources Information Center
Morn, Frank T.
Current developments concerning criminology and criminal justice education are viewed historically and placed within a broader perspective of academic professionalization, and a few of the debates going on within and between the two fields are considered. Some early sociologists made considerable claim to studies of crime, and criminology and…
Teachers' Attitudes toward Technology Integration in Schools: A Four-Year Study
ERIC Educational Resources Information Center
Liu, Yuliang; Szabo, Zsuzsanna
2009-01-01
This trend study was designed to examine a current trend and pattern, as well as a development of teachers' concerns about technology integration in the curriculum. The study was conducted by repeated cross-sectional studies, applying the same research instrument to different samples of subjects at different points, over a period of four years…
Recruitment and Retention of Substance-Using Pregnant and Parenting Women: Lessons Learned.
ERIC Educational Resources Information Center
Laken, Marilyn Poland; Hutchins, Ellen
According to current estimates, approximately 5.5 percent of all American pregnant women use an illicit drug during pregnancy. National concern for drug-exposed infants prompted interest in the needs of substance using pregnant women and in the development of drug treatment programs for them. A total of 147 comprehensive programs have been funded…
On Organizing Educational Research Communication in Europe: Past Experiences and Possible Futures
ERIC Educational Resources Information Center
Lindblad, Sverker
2015-01-01
In this note I will comment on the development of the European Educational Research Association (EERA) as a European educational research organization and the current situation. In doing so I will put forward a few matters concerning the social and intellectual organization of the EERA and the visibility of educational research in Europe.
ERIC Educational Resources Information Center
Hayes, Deborah
2017-01-01
Inactivity amongst children and adults in the UK is currently of great concern. Attitudes towards physical activity develop during childhood and may influence physical activity patterns in later life. This research investigated the experiences and perceptions of physical education (P.E.) amongst primary school pupils. The study established overall…
Suicide Interventions Targeted toward At-Risk Youth
ERIC Educational Resources Information Center
Langhinrichsen-Rohling, Jennifer; Lamis, Dorian A.; McCullars, Adrianne
2012-01-01
Suicide is currently the third leading cause of death among youth; it has been named a public health concern. A number of programs have been developed to prevent suicide; many of these involve intervening with youth who are known to be at-risk because of their depression, expressed suicide ideation, or previous suicide attempts. This paper serves…
The Art of Peace: Dissuading China from Developing Counter Space Weapons
2005-06-01
103 ix ABBREVIATIONS AND ACRONYMS AEGIS Airborne Early Warning Ground Environment Interface Segment AOR Area of...13 Figure 4. Defense Policy Gray Area (Friend or Foe?) ....................................................20 Figure 5. U.S. Defense Policies (at...1 Furthermore, current U.S. leadership has explicitly identified one particular area of concern. In particular, Asia is gradually emerging as a
An Approach to the Development of International Jurisdiction to Deal with Environmental Problems.
ERIC Educational Resources Information Center
Howell, John M.
The purposes of the report are to assess international rules currently available for compulsory settlement of environmental disputes and to describe a basis for jurisdiction by United Nations agencies over disputes not covered by existing rules. A history of international concern with the environment since the Stockholm Conference on the Human…
USDA-ARS?s Scientific Manuscript database
The current outbreak of Zika virus in the Americas has highlighted the need for improved methods of control. This concern is exacerbated if we consider that all three major arboviruses (Zika, dengue, and chikungunya virus) are transmitted efficiently by two wide spread mosquito vectors: Aedes aegypt...
Development of issue-relevant state level analyses of fragmentation and urbanization
Rachel Riemann; Tonya Lister; Andy Lister; Dacia Meneguzzo; Sarah Parks
2009-01-01
There has been considerable research concerning the extent and effect of urbanization and fragmentation and the importance of monitoring current and potential magnitudes of change is recognized. However, there are limited guidelines for interpreting fragmentation data or for their application for analysis and statewide planning efforts. In this study we take a first...
Coggan, J M; Crandall, L A
1995-01-01
The use of rural sites to train badly needed primary care providers requires access to sophisticated medical information not traditionally available outside of academic health centers. Medical reference librarians can play a key role in the development of primary care training sites in rural settings. Electronic information technologies, with proactive support from medical reference librarians, can provide current and detailed information without concern for distance from the health science center library. This paper discusses recent developments in technology, describes current challenges to the application of this technology in rural settings, and provides policy recommendations for medical reference librarians to enhance rural primary care training.
Crowley, Sheila A; Foley, Sallie M; Wittmann, Daniela; Jagielski, Christina H; Dunn, Rodney L; Clark, Patricia M; Griggs, Jennifer J; Peterson, Catherine; Leonard, Marcia; An, Lawrence C; Wei, John T; Montie, James E; Janz, Nancy K
2016-09-01
While it is recognized that cancer treatment can contribute to problems in sexual function, much less is currently known about the specific sexual health concerns and information needs of cancer survivors. This study tested a new instrument to measure cancer survivors' sexual health concerns and needs for sexual information after cancer treatment. The Information on Sexual Health: Your Needs after Cancer (InSYNC), developed by a multidisciplinary team of experts, is a novel 12-item questionnaire to measure sexual health concerns and information needs of cancer survivors. We tested the measure with a sample of breast and prostate cancer survivors. A convenience sample of 114 cancer survivors (58 breast, 56 prostate) was enrolled. Results of the InSYNC questionnaire showed high levels of sexual concern among cancer survivors. Areas of concern differed by cancer type. Prostate cancer survivors were most concerned about being able to satisfy their partners (57 %) while breast cancer survivors were most concerned with changes in how their bodies worked sexually (46 %). Approximately 35 % of all cancer survivors wanted more information about sexual health. Sexual health concerns and unmet information needs are common among breast and prostate cancer survivors, varying in some aspects by type of cancer. Routine screening for sexual health concerns should be included in comprehensive cancer survivorship care to appropriately address health care needs. The InSYNC questionnaire is one tool that may help clinicians identify concerns facing their patients.
Integrating interface slicing into software engineering processes
NASA Technical Reports Server (NTRS)
Beck, Jon
1993-01-01
Interface slicing is a tool which was developed to facilitate software engineering. As previously presented, it was described in terms of its techniques and mechanisms. The integration of interface slicing into specific software engineering activities is considered by discussing a number of potential applications of interface slicing. The applications discussed specifically address the problems, issues, or concerns raised in a previous project. Because a complete interface slicer is still under development, these applications must be phrased in future tenses. Nonetheless, the interface slicing techniques which were presented can be implemented using current compiler and static analysis technology. Whether implemented as a standalone tool or as a module in an integrated development or reverse engineering environment, they require analysis no more complex than that required for current system development environments. By contrast, conventional slicing is a methodology which, while showing much promise and intuitive appeal, has yet to be fully implemented in a production language environment despite 12 years of development.
Kairy, Dahlia; Rushton, Paula W.; Archambault, Philippe; Pituch, Evelina; Torkia, Caryne; El Fathi, Anas; Stone, Paula; Routhier, François; Forget, Robert; Demers, Louise; Pineau, Joelle; Gourdeau, Richard
2014-01-01
Power wheelchairs (PWCs) can have a positive impact on user well-being, self-esteem, pain, activity and participation. Newly developed intelligent power wheelchairs (IPWs), allowing autonomous or collaboratively-controlled navigation, could enhance mobility of individuals not able to use, or having difficulty using, standard PWCs. The objective of this study was to explore the perspectives of PWC users (PWUs) and their caregivers regarding if and how IPWs could impact on current challenges faced by PWUs, as well as inform current development of IPWs. A qualitative exploratory study using individual interviews was conducted with PWUs (n = 12) and caregivers (n = 4). A semi-structured interview guide and video were used to facilitate informed discussion regarding IPWs. Thematic analysis revealed three main themes: (1) “challenging situations that may be overcome by an IPW” described how the IPW features of obstacle avoidance, path following, and target following could alleviate PWUs’ identified mobility difficulties; (2) “cautious optimism concerning IPW use revealed participants” addresses concerns regarding using an IPW as well as technological suggestions; (3) “defining the potential IPW user” revealed characteristics of PWUs that would benefit from IPW use. Findings indicate how IPW use may help overcome PWC difficulties and confirm the importance of user input in the ongoing development of IPWs. PMID:24566051
Kairy, Dahlia; Rushton, Paula W; Archambault, Philippe; Pituch, Evelina; Torkia, Caryne; El Fathi, Anas; Stone, Paula; Routhier, François; Forget, Robert; Demers, Louise; Pineau, Joelle; Gourdeau, Richard
2014-02-21
Power wheelchairs (PWCs) can have a positive impact on user well-being, self-esteem, pain, activity and participation. Newly developed intelligent power wheelchairs (IPWs), allowing autonomous or collaboratively-controlled navigation, could enhance mobility of individuals not able to use, or having difficulty using, standard PWCs. The objective of this study was to explore the perspectives of PWC users (PWUs) and their caregivers regarding if and how IPWs could impact on current challenges faced by PWUs, as well as inform current development of IPWs. A qualitative exploratory study using individual interviews was conducted with PWUs (n = 12) and caregivers (n = 4). A semi-structured interview guide and video were used to facilitate informed discussion regarding IPWs. Thematic analysis revealed three main themes: (1) "challenging situations that may be overcome by an IPW" described how the IPW features of obstacle avoidance, path following, and target following could alleviate PWUs' identified mobility difficulties; (2) "cautious optimism concerning IPW use revealed participants" addresses concerns regarding using an IPW as well as technological suggestions; (3) "defining the potential IPW user" revealed characteristics of PWUs that would benefit from IPW use. Findings indicate how IPW use may help overcome PWC difficulties and confirm the importance of user input in the ongoing development of IPWs.
Developmental neurotoxicants in e-waste: an emerging health concern.
Chen, Aimin; Dietrich, Kim N; Huo, Xia; Ho, Shuk-mei
2011-04-01
Electronic waste (e-waste) has been an emerging environmental health issue in both developed and developing countries, but its current management practice may result in unintended developmental neurotoxicity in vulnerable populations. To provide updated information about the scope of the issue, presence of known and suspected neurotoxicants, toxicologic mechanisms, and current data gaps, we conducted this literature review. We reviewed original articles and review papers in PubMed and Web of Science regarding e-waste toxicants and their potential developmental neurotoxicity. We also searched published reports of intergovernmental and governmental agencies and nongovernmental organizations on e-waste production and management practice. We focused on the potential exposure to e-waste toxicants in vulnerable populations-that is, pregnant women and developing children-and neurodevelopmental outcomes. In addition, we summarize experimental evidence of developmental neurotoxicity and mechanisms. In developing countries where most informal and primitive e-waste recycling occurs, environmental exposure to lead, cadmium, chromium, polybrominated diphenyl ethers, polychlorinated biphenyls, and polycyclic aromatic hydrocarbons is prevalent at high concentrations in pregnant women and young children. Developmental neurotoxicity is a serious concern in these regions, but human studies of adverse effects and potential mechanisms are scarce. The unprecedented mixture of exposure to heavy metals and persistent organic pollutants warrants further studies and necessitates effective pollution control measures. Pregnant women and young children living close to informal e-waste recycling sites are at risk of possible perturbations of fetus and child neurodevelopment.
NASA Astrophysics Data System (ADS)
Olmstead, Dean A.; Schertler, Ronald R.; Randall, Laura A.
1992-03-01
The Advanced Communications Technology Satellite (ACTS), now under development and scheduled for launch in early 1993, is the current focus of NASA's commercial communications satellite program. The full power of the key technologies on ACTS can only be realized if industry assumes an active role in the conduct of experiments and demonstrations. This paper discusses the current market-driven rationale behind the ACTS Experiments Program activities aimed at getting industry involved - a rationale that addresses industry concerns and responds to industry inputs.
Electronic reserves: copyright and permissions
Graves, Karen J.
2000-01-01
Electronic reserves present a new service option for libraries to provide needed materials during hours that the library is not open and to user groups located some distance from library collections. Possible changes to current copyright law and publishers permissions policies have delayed the development of electronic reserves in many libraries. This paper reviews the current state of electronic reserves materials in the publishing and library communities and presents the results of a survey of publishers to determine permissions policies for electronic materials. Issues of concern to both libraries and publishers are discussed. PMID:10658960
Radiation safety standards and their application: international policies and current issues.
González, Abel J
2004-09-01
This paper briefly describes the current policies of the United Nations Scientific Committee on the Effects of Atomic Radiation and the International Commission on Radiological Protection and how these policies are converted into international radiation safety standards by the International Atomic Energy Agency, which is the only global organization-within the United Nations family of international agencies-with a statutory mandate not only to establish such standards but also to provide for their application. It also summarizes the current status of the established corpus of such international standards, and of it foreseeable evolution, as well as of legally binding undertakings by countries around the world that are linked to these standards. Moreover, this paper also reviews some major current global issues related to the application of international standards, including the following: strengthening of national infrastructures for radiation safety, including technical cooperation programs for assisting developing countries; occupational radiation safety challenges, including the protection of pregnant workers and their unborn children, dealing with working environments with high natural radiation levels, and occupational attributability of health effects (probability of occupational causation); restricting discharges of radioactive substances into the environment: reviewing current international policies vis-a-vis the growing concern on the radiation protection of the "environment;" radiological protection of patients undergoing radiodiagnostic and radiotherapeutic procedures: the current International Action Plan; safety and security of radiation sources: post-11 September developments; preparedness and response to radiation emergencies: enhancing the international network; safe transport of radioactive materials: new apprehensions; safety of radioactive waste management: concerns and connections with radiation protection; and radioactive residues remaining after the termination of activities: radiation protection response to the forthcoming wave of decommissioning of installations with radioactive materials. The ultimate aim of this paper is to encourage information exchange, cooperation, and collaboration within the radiation protection professional community. In particular, the paper tries to facilitate consolidation of the growing international regime on radiation safety, including the expansion of legally binding undertakings by countries, the strengthening of the current corpus of international radiation safety standards, and the development of international provisions for ensuring the proper worldwide application of these standards, such as a system of international appraisals by peer review.
Is it only the regulatory status? Broadening the debate on cisgenic plants.
van Hove, Lilian; Gillund, Frøydis
2017-01-01
In current debates on emerging technologies for plant breeding in Europe, much attention has been given to the regulatory status of these techniques and their public acceptance. At present, both genetically modified plants with cisgenic approaches-using genes from crossable species-as well as transgenic approaches-using genes from different species-fall under GMO regulation in the EU and both are mandatorily labelled as GMOs. Researchers involved in the early development of cisgenic GM plants convey the message that the potential use and acceptance of cisgenic approaches will be seriously hindered if GMO regulations are not adjusted. Although the similar treatment and labelling of transgenic and cisgenic plants may be a legitimate concern for the marketability of a cisgenic GM plant, there are concerns around their commercialization that reach beyond the current focus on (de)regulation. In this paper, we will use the development of the cisgenic GM potato that aims to overcome 'late blight'-the most devastating potato disease worldwide-as a case to argue that it is important to recognize, reflect and respond to broader concerns than the dominant focus on the regulatory 'burden' and consumer acceptance. Based on insights we gained from discussing this case with diverse stakeholders within the agricultural sector and potato production in Norway during a series of workshops, we elaborate on additional issues such as the (technical) solution offered; different understandings of the late blight problem; the durability of the potato plant resistance; and patenting and ownership. Hence, this paper contributes to empirical knowledge on stakeholder perspectives on emerging plant breeding technologies, underscoring the importance to broaden the scope of the debate on the opportunities and challenges of agricultural biotechnologies, such as cisgenic GM plants. The paper offers policy-relevant input to ongoing efforts to broaden the scope of risk assessments of agricultural biotechnologies. We aim to contribute to the recognition of the complex socio-ecological, legal and political dimensions in which these technological developments are entangled as a means to acknowledge, discuss and respond to these concerns and thereby contribute to more comprehensive and responsible developments within agricultural biotechnology.
Domain analysis for the reuse of software development experiences
NASA Technical Reports Server (NTRS)
Basili, V. R.; Briand, L. C.; Thomas, W. M.
1994-01-01
We need to be able to learn from past experiences so we can improve our software processes and products. The Experience Factory is an organizational structure designed to support and encourage the effective reuse of software experiences. This structure consists of two organizations which separates project development concerns from organizational concerns of experience packaging and learning. The experience factory provides the processes and support for analyzing, packaging, and improving the organization's stored experience. The project organization is structured to reuse this stored experience in its development efforts. However, a number of questions arise: What past experiences are relevant? Can they all be used (reused) on our current project? How do we take advantage of what has been learned in other parts of the organization? How do we take advantage of experience in the world-at-large? Can someone else's best practices be used in our organization with confidence? This paper describes approaches to help answer these questions. We propose both quantitative and qualitative approaches for effectively reusing software development experiences.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Faydide, B.
1997-07-01
This paper presents the current and planned numerical development for improving computing performance in case of Cathare applications needing real time, like simulator applications. Cathare is a thermalhydraulic code developed by CEA (DRN), IPSN, EDF and FRAMATOME for PWR safety analysis. First, the general characteristics of the code are presented, dealing with physical models, numerical topics, and validation strategy. Then, the current and planned applications of Cathare in the field of simulators are discussed. Some of these applications were made in the past, using a simplified and fast-running version of Cathare (Cathare-Simu); the status of the numerical improvements obtained withmore » Cathare-Simu is presented. The planned developments concern mainly the Simulator Cathare Release (SCAR) project which deals with the use of the most recent version of Cathare inside simulators. In this frame, the numerical developments are related with the speed up of the calculation process, using parallel processing and improvement of code reliability on a large set of NPP transients.« less
Growing better brains? Pregnancy and neuroscience discourses in English social and welfare policies
Lowe, Pam; Lee, Ellie; Macvarish, Jan
2015-01-01
In recent years, English welfare and health policy has started to include pregnancy within the foundation stage of child development. The foetus is also increasingly designated as ‘at risk’ from pregnant women. In this article, we draw on an analysis of a purposive sample of English social and welfare policies and closely related advocacy documents to trace the emergence of neuroscientific claims-making in relation to the family. In this article, we show that a specific deterministic understanding of the developing brain that only has a loose relationship with current scientific evidence is an important component in these changes. We examine the ways in which pregnancy is situated in these debates. In these debates, maternal stress is identified as a risk to the foetus; however, the selective concern with women living in disadvantage undermines biological claims. The policy claim of neurological ‘critical windows’ also seems to be influenced by social concerns. Hence, these emerging concerns over the foetus’ developing brain seem to be situated within the gendered history of policing women’s pregnant bodies rather than acting on new insights from scientific discoveries. By situating these developments within the broader framework of risk consciousness, we can link these changes to wider understandings of the ‘at risk’ child and intensified surveillance over family life. PMID:25810690
NASA Technical Reports Server (NTRS)
Wolf, R. A.; Kamide, Y.
1983-01-01
Advanced techniques considered by Kamide et al. (1981) seem to have the potential for providing observation-based high time resolution pictures of the global ionospheric current and electric field patterns for interesting events. However, a reliance on the proposed magnetogram-inversion schemes for the deduction of global ionospheric current and electric field patterns requires proof that reliable results are obtained. 'Theoretical' tests of the accuracy of the magnetogram inversion schemes have, therefore, been considered. The present investigation is concerned with a test, involving the developed KRM algorithm and the Rice Convection Model (RCM). The test was successful in the sense that there was overall agreement between electric fields and currents calculated by the RCM and KRM schemes.
Answering Public Health Concerns Over Japanese Nuclear Disaster | ORAU
Allen, Leeanna; Vasconez, Rachel
2018-05-11
When the Fukushima Daiichi Nuclear Power Plant became crippled following Japan's March 2011 earthquake and tsunami, some U.S. citizens became concerned about whether radiation would disperse across the Pacific Ocean. As the Centers for Disease Control and Prevention prepared to assist in the U.S. response effort, ORAU provided the CDC with onsite, staff support at its Joint Information Center. ORAU also had a lead role in the development and execution of the CDC's first-ever Bridging the Gaps: Public Health and Radiation Emergency Preparedness conference, which took place 10 days after the earthquake and served as a forum for discussing the current state of radiation emergency preparedness.
Bad bugs, no drugs: no ESKAPE! An update from the Infectious Diseases Society of America.
Boucher, Helen W; Talbot, George H; Bradley, John S; Edwards, John E; Gilbert, David; Rice, Louis B; Scheld, Michael; Spellberg, Brad; Bartlett, John
2009-01-01
The Infectious Diseases Society of America (IDSA) continues to view with concern the lean pipeline for novel therapeutics to treat drug-resistant infections, especially those caused by gram-negative pathogens. Infections now occur that are resistant to all current antibacterial options. Although the IDSA is encouraged by the prospect of success for some agents currently in preclinical development, there is an urgent, immediate need for new agents with activity against these panresistant organisms. There is no evidence that this need will be met in the foreseeable future. Furthermore, we remain concerned that the infrastructure for discovering and developing new antibacterials continues to stagnate, thereby risking the future pipeline of antibacterial drugs. The IDSA proposed solutions in its 2004 policy report, "Bad Bugs, No Drugs: As Antibiotic R&D Stagnates, a Public Health Crisis Brews," and recently issued a "Call to Action" to provide an update on the scope of the problem and the proposed solutions. A primary objective of these periodic reports is to encourage a community and legislative response to establish greater financial parity between the antimicrobial development and the development of other drugs. Although recent actions of the Food and Drug Administration and the 110th US Congress present a glimmer of hope, significant uncertainly remains. Now, more than ever, it is essential to create a robust and sustainable antibacterial research and development infrastructure--one that can respond to current antibacterial resistance now and anticipate evolving resistance. This challenge requires that industry, academia, the National Institutes of Health, the Food and Drug Administration, the Centers for Disease Control and Prevention, the US Department of Defense, and the new Biomedical Advanced Research and Development Authority at the Department of Health and Human Services work productively together. This report provides an update on potentially effective antibacterial drugs in the late-stage development pipeline, in the hope of encouraging such collaborative action.
The Water-Energy-Food Nexus in a Rapidly Developing Resource Sector
NASA Astrophysics Data System (ADS)
Allen, D. M.; Kirste, D. M.
2014-12-01
Technological advances and access to global markets have changed the rate at which resource exploitation takes place. The environmental impact of the rapid development and distribution of resources such as minerals and hydrocarbons has led to a greater potential for significant stress on water resources both in terms of quality and quantity. How and where those impacts manifest is crucial to determining appropriate risk management strategies. North East British Columbia has an abundance of shale gas reserves that are anticipated to be exploited at a large scale in coming years, primarily for export as liquefied natural gas (LNG). However, there is growing concern that fracking and other activities related to shale gas development pose risks to water quality and quantity in the region. Water lies at the center of the water-energy-food nexus, with an accelerating water demand for fracking and industrial operations as well as for domestic, environmental and agricultural uses. Climate change is also anticipated to alter the hydrologic regime, posing added stress to the water resource. This case study examines the water-energy-food nexus in the context of a region that is impacted by a rapidly developing resource sector, encompassing water demand/supply, climate change, interaction between deep aquifers and shallow aquifers/surface waters, water quality concerns related to fracking, land use disturbance, and community impacts. Due to the rapid rate of development, there are significant knowledge gaps in our understanding of the water resource. Currently agencies are undertaking water resource assessments and establishing monitoring sites. This research aims to assess water security in North East British Columbia in a coordinated fashion through various partnerships. In addition to collecting baseline knowledge and data, the study will evaluate risk and resilience indicators in relation to water security. A risk assessment framework specific to the shale gas development context will be developed to evaluate the various components of risk spatially and temporally. Resilience is currently being assessed through a comprehensive examination of the current regulatory and policy regime.
Limits of acceptable change as tool for tourism development sustainability in Pangandaran West Java
NASA Astrophysics Data System (ADS)
Komsary, K. C.; Tarigan, W. P.; Wiyana, T.
2018-03-01
Pangandaran since 2006 has become a model of sustainable tourism development. A program aimed to empower local communities to prepare work plans and activities to enrich the various potential development of sustainable tourism. By empowering local community, business competition has led to the undesired development of the tourism sector. This becomes the concern of the negative impact of physical changes in the area. This study aims to identify and measure the acceptable changes (limits of acceptable change-LAC) of tourism development in Pangandaran to remain adaptable as a tourist attraction. This study considers how to determine acceptable levels of impact that occurs in the Pangandaran area. This method involves stakeholders in determining the values, issues, and concerns the acceptable levels of impact for this region. The result of acceptance rate then compared with the effects of the current state. Through review and analysis methods used in this study, the LAC situation in Pangandaran outlined. Results from this study are expected to identify indicators of sustainable development of tourism sector through LAC approach.
EMERGING ENVIRONMENTAL CONTAMINANTS AND CURRENT ISSUES
Much has been achieved in the way of environmental protection over the last 30 years. However, as we learn more, new concerns arise. This presentation will discuss emerging environmental contaminants that the U.S. EPA and other agencies are currently concerned about. Emerging c...
Cornish, Amelia; Raubenheimer, David; McGreevy, Paul
2016-11-16
Population growth and rising consumption of meat, dairy, eggs and fish are forcing the world to face the intersecting challenges of how to sustainably feed a population expected to exceed 9 billion by 2050, while also controlling the impact of food production on the planet, on people and on animals. This review acknowledges the absence of a globally accepted definition of animal welfare and then explores the literature regarding different levels of concern for animal welfare in food production by such stakeholders as veterinarians, farmers, and the general public. It focuses on the evidence that the general public's level of concern for animal welfare is linked to various demographic and personal characteristics, such as age, gender, religion, location, meat eating, and knowledge of animal welfare. Certain animals have characteristics that influence concern for their welfare, with those species that are considered more intelligent being afforded more concern. There is compelling evidence that the general public's understanding of animal welfare in food production is poor. Acknowledging that public concern can be a driving force to change current production methods, the authors suggest widespread consciousness raising to redefine socially acceptable methods of food production from animals and to ensure that it remains in step with societal concerns.
Zoonotic diseases: health aspects of Canadian geese.
Dieter, R A; Dieter, R S; Dieter, R A; Gulliver, G
2001-11-01
Review zoonotic diseases associated with Canadian geese. Review article: A review of the multiple physical, microbiologic and safety concerns, and methods used in controlling this potential problem. Over the last decade the Canadian goose population (protected by international treaties and protection acts) has increased rapidly such that in many cities they have become a pest rather than an admired wild bird. Their increasing numbers have caused a number of potential healthcare concerns including: physical, bacterial, parasitic, allergic and viral potential problems. The Canadian goose fecal droppings of one per minute have caused falls and the flying geese have caused air traffic accidents. Bacterial concerns, including botulism, salmonella and E. coli have all been reviewed and presented concerns. The viral Newcastle disease may be detected with hemagglutination studies and the Giardia psittaci parasites have been repeatedly found in their droppings. The Cryptosporidium parvum oocytes have been present on stool study. Definite links to human infectious diseases have been difficult to prove. Revision of the current laws and new control programs must be developed.
ENVIRONMENTAL CHEMISTRY: EMERGING CONTAMINANTS AND CURRENT ISSUES
Much has been achieved in the way of environmental protection over the last 30 years. However, as we learn more, new concerns arise. This presentation will discuss chemical and microbial contaminants that the U.S. EPA and other agencies are currently concerned about. In this gr...
ERIC Educational Resources Information Center
Wozniak, Carl
2010-01-01
Administrator perspectives regarding current and potential increased participation in post-secondary educational opportunities by Michigan high school students were explored in this descriptive quantitative study. Targeted concerns included current institutional levels of involvement, personal knowledge concerning program rules and regulations,…
Comprehensive Nuclear-Test-Ban Treaty: Background and Current Developments
2013-06-10
subcritical; that is, no critical mass is formed and no self-sustaining nuclear chain reaction can occur; thus, there is no nuclear explosion.”211 SCEs...45 The National Academy of Sciences Study and Its Critics ...the future, but there are no plans to do so.”8 Critics expressed concern about the implications of these policies for testing and new weapons
Comprehensive Nuclear-Test-Ban Treaty: Background and Current Developments
2012-08-03
Academy of Sciences Study and Its Critics ....................................................... 39 Chronology... criticisms of that report. On February 13, the Administration rolled out its FY2013 budget request, which included funds for the CTBT Organization...So he has not ruled out testing in the future, but there are no plans to do so.”4 Critics expressed concern about the implications of these policies
ERIC Educational Resources Information Center
Wildemeersch, Danny, Ed.; Finger, Matthias, Ed.; Jansen, Theo, Ed.
In this book, 16 authors from Europe, Africa, and the United States reflect on the transformations that are currently taking place in the field of adult and continuing education. The 12 chapters are "Reconciling the Irreconcilable? Adult and Continuing Education Between Personal Development, Corporate Concerns, and Public Responsibility"…
ERIC Educational Resources Information Center
Farrell, R. V.; Papagiannis, George
This study examines the advocacy of education for sustainability in a contemporary world driven by the powerful forces of globalization and development. A brief overview of the current ecological crisis in the world is presented, and concerns about environmental degradation, social injustice, and social inequalities are discussed. The vision of…
ERIC Educational Resources Information Center
Association of American Colleges, Washington, DC. Project on the Status and Education of Women.
Educators are increasingly seeking information about minority women as they attempt to develop realistic, viable programs to benefit them. This paper summarizes some of the relevant data concerning the educational and economic status of Spanish speaking women. Whenever possible, ethnic variations are noted. In general, the data are divided into…
ERIC Educational Resources Information Center
Butterfield, Barbara; Forrester, Tricia; McCallum, Faye; Chinnappan, Mohan
2013-01-01
A current concern is student learning outcomes and these are largely a function of teachers' knowledge and their practice. This position paper is premised on the notion that certain knowledge is required for the teaching of mathematics. An exploration of literature demonstrates that such professional knowledge development can be supported by…
Just Care: Learning from and with Graduate Students in a Doctor of Nursing Practice Program
ERIC Educational Resources Information Center
Boquet, Elizabeth; Kazer, Meredith; Manister, Nancy; Lucas, Owen; Shaw, Michael; Madaffari, Valerie; Gannett, Cinthia
2015-01-01
In 2010, Fairfield University, a Jesuit Carnegie Masters Level 1 University located in the Northeast, established its first doctoral-level program: the Doctorate of Nursing Practice (DNP). In a developing program such as the DNP, some of the most pressing concerns of current rhetoric and writing in the disciplines align and interact with the…
ERIC Educational Resources Information Center
Mecca, Christyna E.
Listed in this directory are individuals concerned currently with marine activities on the coasts of North Carolina, South Carolina, and Georgia, and the adjacent offshore area, known administratively as the Coastal Plains Region. The categories for the listings include educational institutions, state and county agencies, and federal agencies. The…
ERIC Educational Resources Information Center
Hayward, E. Louise; Hutchinson, Carolyn
2013-01-01
Scotland, in common with many other countries internationally, has paid considerable attention to the development of assessment for learning. Currently, schools in Scotland are engaged in a major programme of curriculum and assessment reform, entitled Curriculum for Excellence. As part of the reform process, there is concern amongst practitioners,…
ERIC Educational Resources Information Center
Tulodziecki, Gerhard; Grafe, Silke
2012-01-01
German approaches to media literacy education are concerned with the questions, how the variety of media can be used in a meaningful way for learning and teaching and what educational tasks result from the extensive use of media. Considering these questions there are various conceptual ideas, research and development projects as well as…
ERIC Educational Resources Information Center
Miyake, Saori; Renouf, Marguerite; Peterson, Ann; McAlpine, Clive; Smith, Carl
2012-01-01
Recent energy and climate policies, particularly in the developed world, have increased demand for bioenergy as an alternative, which has led to both direct and indirect land-use changes and an array of environmental and socio-economic concerns. A comprehensive understanding of the land-use dynamics of bioenergy crop production is essential for…
Novel Magnetic Fluids for Breast Cancer Therapy
2005-04-01
synthesis and characterization efforts concerning nickel-based alloys have been reported previously [5]. Nano-material has been obtained using an inverse...gar gel d ork his task regularly accompanies the synthesis work. Characterization analysis includes size, composition, magnetic pro perties. The...currently available magnetic fluids used in hyperthermia. The specific goals are: 1. Develop a synthesis process to fabricate magnetic nano
ERIC Educational Resources Information Center
Austin, Vance L.
2011-01-01
This article presents the findings of a short-term quantitative/qualitative study concerning the attitudes of Vietnamese educators towards individuals with disabilities and its possible implications relative to the development of inclusion and special education in Vietnam. The current conditions regarding the education of students with and without…
ERIC Educational Resources Information Center
Valette, Rebecca M.; Linder, Cathy
Current developments in the field of language testing are synthesized with emphasis on their practical application in the classroom. The main areas of concern are: (1) the role of testing in the schools; (2) identifying and measuring teacher and student variables, such as, language proficiency of teachers; teacher effectiveness in the classroom;…
ERIC Educational Resources Information Center
Keddie, Amanda
2009-01-01
This paper tracks the development of gender equity and schooling policy in Australia from the "National Policy on the Education of Girls in 1987", to current policy concerns with boys' educational underperformance. The paper's key focus is on the ways in which feminist informed equity policy has been undermined by broader imperatives of…
ERIC Educational Resources Information Center
Smith, Elaine Lois
2012-01-01
Quality and safety in healthcare is a national concern. It has been proposed that nurses and other clinicians need to develop a new set of competencies in order to make significant improvements in the quality and safety of patient care. These new competencies include: patient-centered care; teamwork and collaboration; evidence-based practice;…
Labour Market Developments and Their Significance for VET in England: Current Concerns and Debates
ERIC Educational Resources Information Center
Laczik, Andrea; Mayhew, Ken
2015-01-01
This chapter discusses the relationship between the labour market and vocational education and training in England. For decades British governments have emphasised the need for more people to stay longer in the formal education system and at the same time have attempted to improve work-based training. They have also emphasised the centrality of…
The worldwide epidemiology of acute rheumatic fever and rheumatic heart disease
Seckeler, Michael D; Hoke, Tracey R
2011-01-01
Acute rheumatic fever (ARF) and rheumatic heart disease (RHD) are significant public health concerns around the world. Despite decreasing incidence, there is still a significant disease burden, especially in developing nations. This review provides background on the history of ARF, its pathology and treatment, and the current reported worldwide incidence of ARF and prevalence of RHD. PMID:21386976
Current Issues: Critical Issues Confronting the Nation and the World. 1989 Edition.
ERIC Educational Resources Information Center
Sass, Charles R., Ed.
This book investigates a variety of contemporary issues, both domestic U.S. concerns and those of an international focus that involve the United States. The introduction develops the context of the book by discussing the Reagan legacy, the 101st Congress, the Supreme Court, and the making of the U.S. federal budget. The domestic policy issues of…
Adderall for All: A Defense of Pediatric Neuroenhancement.
Flanigan, Jessica
2013-08-20
I argue that young patients should be able to access neuroenhancing drugs without a diagnosis of ADHD. The current framework of consent for pediatric patients can be adapted to accommodate neuroenhancement. After a brief overview of pediatric neuroenhancement, I develop three arguments in favor of greater acceptance of neuroenhancement for young patients. First, ADHD is not relevantly different from other disadvantages that could be treated with stimulant medication. Second, establishing a legitimate framework for pediatric neuroenhancement would mitigate the bad effects of diversion and improve research on neuroenhancement and ADHD. Third, some pediatric patients have rights to access neuroenhancements. I then consider several objections to pediatric neuroenhancement. I address concerns about addiction, advertising, authentic development, the parent-child relationship and equal opportunity and conclude that these concerns may inform a framework for prescribing neuroenhancement but they do not justify limits on prescribing.
Sridhar, Devi
2008-01-01
This paper discusses the politics of access to essential medicines and identifies ‘space’ in the current system where health concerns can be strengthened relative to trade. This issue is addressed from a global governance perspective focusing on the main actors who can have the greatest impact. These include developing country coalitions and citizens in developed countries though participation in civil society organisations. These actors have combined forces to tackle this issue successfully, resulting in the 2001 Doha Declaration on Public Health. The collaboration has been so powerful due to the assistance of the media as well as the decision to compromise with pharmaceutical companies and their host countries. To improve access to essential medicines, six C's are needed: coalitions, civil society, citizenship, compromise, communication and collaboration. PMID:19461853
An improved source model for aircraft interior noise studies
NASA Technical Reports Server (NTRS)
Mahan, J. R.; Fuller, C. R.
1985-01-01
There is concern that advanced turboprop engines currently being developed may produce excessive aircraft cabin noise levels. This concern has stimulated renewed interest in developing aircraft interior noise reduction methods that do not significantly increase take off weight. An existing analytical model for noise transmission into aircraft cabins was utilized to investigate the behavior of an improved propeller source model for use in aircraft interior noise studies. The new source model, a virtually rotating dipole, is shown to adequately match measured fuselage sound pressure distributions, including the correct phase relationships, for published data. The virtually rotating dipole is used to study the sensitivity of synchrophasing effectiveness to the fuselage sound pressure trace velocity distribution. Results of calculations are presented which reveal the importance of correctly modeling the surface pressure phase relations in synchrophasing and other aircraft interior noise studies.
An improved source model for aircraft interior noise studies
NASA Technical Reports Server (NTRS)
Mahan, J. R.; Fuller, C. R.
1985-01-01
There is concern that advanced turboprop engines currently being developed may produce excessive aircraft cabin noise level. This concern has stimulated renewed interest in developing aircraft interior noise reduction methods that do not significnatly increase take off weight. An existing analytical model for noise transmission into aircraft cabins was utilized to investigate the behavior of an improved propeller source model for use in aircraft interior noise studies. The new source model, a virtually rotating dipole, is shown to adequately match measured fuselage sound pressure distributions, including the correct phase relationships, for published data. The virtually rotating dipole is used to study the sensitivity of synchrophasing effectiveness to the fuselage sound pressure trace velocity distribution. Results of calculations are presented which reveal the importance of correctly modeling the surface pressure phase relations in synchrophasing and other aircraft interior noise studies.
The mental and physical health of homeless youth: a literature review.
Edidin, Jennifer P; Ganim, Zoe; Hunter, Scott J; Karnik, Niranjan S
2012-06-01
Youth homelessness is a growing concern in the United States. Despite difficulties studying this population due to inconsistent definitions of what it means to be a youth and homeless, the current body of research indicates that abuse, family breakdown, and disruptive family relationships are common contributing factors to youth homelessness. Moreover, the experience of homelessness appears to have numerous adverse implications and to affect neurocognitive development and academics, as well as mental and physical health. Substance use, sexually transmitted infections, and psychiatric disorders are particularly prevalent in this population. Whereas some of these problems may be short-lived, the chronic stress and deprivation associated with homelessness may have long-term effects on development and functioning. Further, difficulties accessing adequate and developmentally-appropriate health care contribute to more serious health concerns. Suggestions for future research and interventions are discussed.
Asteroseismology and the Virtual Observatory
NASA Astrophysics Data System (ADS)
Suárez, J. C.
2010-12-01
Virtual Observatory is an international project aiming at solving the problem of interoperability among astronomical archives and the scalability in the classical methods of retrieving and analyzing astronomical data in order to deal with huge amounts of datasets. This is being tackled thanks to the standardization of astronomical archives favoring their access in a efficient manner. This project, which is nowadays a reality, is more and more adopted by many fields of Science. In the present paper I will describe the origin of a new era in Stellar Physics whose main role is played by the relationship between asteroseismology and V.O. I will summarize the main concerns of both fields and the current development of VO tools for the development of what we could name as asteroseismology online, in which not only observed datasets are concerned but also the management of model databases.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Owens, J. E.; Vu, A. K.; Esser, B. K.
2010-08-20
The Groundwater Ambient Monitoring and Assessment (GAMA) Program is a comprehensive groundwater quality monitoring program managed by the California State Water Resources Control Board (SWRCB). The GAMA Special Studies project provides analyses and interpretation of constituents of concern that allow assessment of current groundwater conditions. In addition, the Special Studies project develops analyses that will enhance the monitoring and assessment effort by focusing on specific constituents of concern and water quality parameters, such as disinfection byproducts (DBP), wastewater indicators, and redox conditions, as it relates to irrigation and groundwater management. This study developed a robust analytical method for the quantitationmore » of CBZ, OXC, CBZ-E, CBZ-DiOH, and CBZ-10-OH in wastewater treatement plant (WWTP) effluent and in groundwater in the parts per trillion range.« less
A review of electric propulsion systems and mission applications
NASA Technical Reports Server (NTRS)
Vondra, R.; Nock, K.; Jones, R.
1984-01-01
The satisfaction of growing demands for access to space resources will require new developments related to advanced propulsion and power technologies. A key technology in this context is concerned with the utilization of electric propulsion. A brief review of the current state of development of electric propulsion systems on an international basis is provided, taking into account advances in the USSR, the U.S., Japan, West Germany, China and Brazil. The present investigation, however, is mainly concerned with the U.S. program. The three basic types of electric thrusters are considered along with the intrinsic differences between chemical and electric propulsion, the resistojet, the augmented hydrazine thruster, the arcjet, the ion auxiliary propulsion system flight test, the pulsed plasma thruster, magnetoplasmadynamic propulsion, a pulsed inductive thruster, and rail accelerators. Attention is also given to the applications of electric propulsion.
Receptivity to transformative change in the Dutch urban water management sector.
de Graaf, R E; Dahm, R J; Icke, J; Goetgeluk, R W; Jansen, S J T; van de Ven, F H M
2009-01-01
Worldwide, the need for transformative change in urban water management is acknowledged by scientists and policy makers. The effects of climate change and developments such as urbanization, the European Water Framework Directive, and societal concerns about the sustainability of urban water system force the sector to adapt. In The Netherlands, a shift towards integration of spatial planning and water management can be observed. Despite major changes in water management policy and approach, changes in the physical urban water management infrastructure remain limited to incremental solutions and demonstration projects. Policy studies show that institutional factors and professional perceptions are important factors for application of innovations in urban water management. An online survey among Dutch urban water management professionals demonstrates that according to most respondents, optimization of the current system is sufficient to achieve both European and national objectives for sustainable urban water management. The respondents are most concerned with the effects of climate change on urban water systems. In contrast to current policy of the national government, priority factors that should be addressed to achieve a more sustainable urban water system are improving knowledge of local urban water systems, capacity building, developing trust between stakeholders, and improving involvement of elected officials and citizens.
Geodynamics in Modular Course System at Vienna High School
NASA Astrophysics Data System (ADS)
Pitzl-Reinbacher, Robert
2017-04-01
In Austria there are currently some major reforms concerning high school education underway. At our school, the Bundesgymnasium and Bundesrealgymnasium Draschestrasse, a school belonging to the Vienna Bilingual Schooling branch, we have developed a course system in which pupils can select courses and determine individually which areas of study they want to focus on. Specially devised courses have been developed which fit within the framework of natural and applied sciences but go beyond the basic curriculum in physics. Geodynamics is the title of one of these courses, with an emphasis on weather, climate and geodynamic processes of the earth's crust. The course „The restless earth" deals specifically with plate tectonics, vulcanism, formation of mountains and processes such as ocean currents and the physics involved. Apart from theoretical basics we use manifold media and approaches concerning visualization: graphics, map data taken from Google Maps, satellite pictures, and others. The knowledge acquired in this course is broadened and consolidated by means of excursions to the Vienna Natural History Museum where additional instructional materials and visual aids are on display. Based on this experience pupils are requested to hold presentations (individually or in groups) at the end of the course.
Trends in ecosystem service research: early steps and current drivers.
Vihervaara, Petteri; Rönkä, Mia; Walls, Mari
2010-06-01
Over the past 50 years, human beings have influenced ecosystems more rapidly than at any similar time in human history, drastically altering ecosystem functioning. Along with ecosystem transformation and degradation, a number of studies have addressed the functioning, assessment and management of ecosystems. The concept of ecosystem services has been developed in the scientific literature since the end of the 1970s. However, ecosystem service research has focused on certain service categories, ecosystem types, and geographical areas, while substantial knowledge gaps remain concerning several aspects. We assess the development and current status of ecosystem service research on the basis of publications collected from the Web of Science. The material consists of (1) articles (n = 353) from all the years included in the Web of Science down to the completion of the Millennium Ecosystem Assessment and (2) more recent articles (n = 687) published between 2006 and 2008. We also assess the importance of international processes, such as the Convention on Biological Diversity, the Kyoto Protocol and the Millennium Ecosystem Assessment, as drivers of ecosystem service research. Finally, we identify future prospects and research needs concerning the assessment and management of ecosystem services.
Faulkner, Larry R; Tivnan, Patricia W; Winstead, Daniel K; Reus, Victor I; Andrade, Naleen N; Brooks, Beth Ann; Colenda, Christopher C; Mrazek, David A; Reifler, Burton V; Schneidman, Barbara
2008-01-01
To describe the American Board of Psychiatry and Neurology (ABPN) Maintenance of Certification Program, its underlying rationale, how it will be implemented now, and what it might look like in the future. The authors describe the philosophical foundation, specific components, and the implementation timeline of the ABPN Maintenance of Certification Program; the development of specific products that might be used by ABPN diplomates to meet its requirements; and several unanswered questions about its current status and future development. The ABPN Maintenance of Certification Program consists of specific requirements pertaining to professional standing, self-assessment and lifelong learning, performance in practice, and cognitive expertise that will be implemented incrementally over the next decade. The ABPN Maintenance of Certification Program has been implemented in a manner that is as consistent as possible with its underlying philosophical beliefs as well as the current and expected public and political concerns, diplomate needs, and the requirements of organizations responsible for licensure, credentialing, privileging, accreditation, professional development, and physician reimbursement.
1982-04-23
explained the limited scope of his study and in doing so shed some light on the current thought concerning Schofield’s later career: Viewing the Civil War...war became the preoc- cupation of military forces in times of peace. In light of these developments, officership became universally recog- nized as a...calculated method of combat leadership reflected his urbane , sophisticated personality. While he did not achieve the spectacular results that commanders
Recent advances in the development and transfer of machine vision technologies for space
NASA Technical Reports Server (NTRS)
Defigueiredo, Rui J. P.; Pendleton, Thomas
1991-01-01
Recent work concerned with real-time machine vision is briefly reviewed. This work includes methodologies and techniques for optimal illumination, shape-from-shading of general (non-Lambertian) 3D surfaces, laser vision devices and technology, high level vision, sensor fusion, real-time computing, artificial neural network design and use, and motion estimation. Two new methods that are currently being developed for object recognition in clutter and for 3D attitude tracking based on line correspondence are discussed.
A ranking algorithm for spacelab crew and experiment scheduling
NASA Technical Reports Server (NTRS)
Grone, R. D.; Mathis, F. H.
1980-01-01
The problem of obtaining an optimal or near optimal schedule for scientific experiments to be performed on Spacelab missions is addressed. The current capabilities in this regard are examined and a method of ranking experiments in order of difficulty is developed to support the existing software. Experimental data is obtained from applying this method to the sets of experiments corresponding to Spacelab mission 1, 2, and 3. Finally, suggestions are made concerning desirable modifications and features of second generation software being developed for this problem.
Third-Party Software's Trust Quagmire.
Voas, J; Hurlburt, G
2015-12-01
Current software development has trended toward the idea of integrating independent software sub-functions to create more complete software systems. Software sub-functions are often not homegrown - instead they are developed by unknown 3 rd party organizations and reside in software marketplaces owned or controlled by others. Such software sub-functions carry plausible concern in terms of quality, origins, functionality, security, interoperability, to name a few. This article surveys key technical difficulties in confidently building systems from acquired software sub-functions by calling out the principle software supply chain actors.
NASA Technical Reports Server (NTRS)
Smith, C. C.; Warner, D. B.; Dajani, J. S.
1977-01-01
The technical, economic, and environmental problems restricting commercial helicopter passenger operations are reviewed. The key considerations for effective assessment procedures are outlined and a preliminary model for the environmental analysis of helicopters is developed. It is recommended that this model, or some similar approach, be used as a common base for the development of comprehensive environmental assessment methods for each of the federal agencies concerned with helicopters. A description of the critical environmental research issues applicable to helicopters is also presented.
Blanchard, Jack J; Kring, Ann M; Horan, William P; Gur, Raquel
2011-03-01
Negative symptoms in schizophrenia are related to poor functional outcome, persistent over time, a source of burden for caregivers, and only minimally responsive to currently available medications. A major challenge to developing efficacious interventions concerns the valid and reliable assessment of negative symptoms. In a recent consensus statement on negative symptoms, a central recommendation was the need to develop new assessment approaches that address the limitations of existing instruments. In the current report, we summarize the background and rationale for the Collaboration to Advance Negative Symptom Assessment in Schizophrenia (CANSAS). The CANSAS project is an National Institute of Mental Health-funded multisite study that is constructing a next-generation negative symptom scale, the Clinical Assessment Interview for Negative Symptoms (CAINS). The CAINS is being developed within a data-driven iterative process that seeks to ensure the measure's reliability, validity, and utility for both basic psychopathology and treatment development research.
Vasseur, Liette; Horning, Darwin; Thornbush, Mary; Cohen-Shacham, Emmanuelle; Andrade, Angela; Barrow, Ed; Edwards, Steve R; Wit, Piet; Jones, Mike
2017-11-01
Sustainable development aims at addressing economic, social, and environmental concerns, but the current lack of responsive environmental governance hinders progress. Short-term economic development has led to limited actions, unsustainable resource management, and degraded ecosystems. The UN Sustainable Development Goals (SDGs) may continue to fall short of achieving significant progress without a better understanding of how ecosystems contribute to achieving sustainability for all people. Ecosystem governance is an approach that integrates the social and ecological components for improved sustainability and includes principles such as adaptive ecosystem co-management, subsidiarity, and telecoupling framework, as well as principles of democracy and accountability. We explain the importance of ecosystem governance in achieving the SDGs, and suggest some ways to ensure that ecosystem services are meaningfully considered. This paper reflects on how integration of these approaches into policies can enhance the current agenda of sustainability.
Federal Register 2010, 2011, 2012, 2013, 2014
2013-08-16
... lack of current and accurate information concerning the securities of Cargo Connection Logistics... Group BDC, Inc., Cargo Connection Logistics Holding, Inc., Diapulse Corporation of America, Globus... current and accurate information concerning the securities of Altus Pharmaceuticals, Inc. because it has...
Current Concerns for Austrian School Facilities.
ERIC Educational Resources Information Center
Schwarz-Viechtbauer, Karin
2003-01-01
Summarizes four recent concerns of the Austrian Institute for School and Sport Facilities, which is responsible for current issues and problems related to educational buildings in the country: schools as low energy buildings, electromagnetic fields and school buildings, chairs and tables for educational buildings, and school grounds (learnscapes).…
ENVIRONMENTAL MASS SPECTROMETRY: EMERGING CONTAMINANTS AND CURRENT ISSUES
Much has been achieved in the way of environmental protection over the last 30 years. However, as we learn more, new concerns arise. This presentation will discuss chemical and microbial contaminants that the U.S. EPA and other agencies are currently concerned about. In this gr...
Slater, Amy; Tiggemann, Marika
2006-07-01
This study aimed to investigate the effects of both past and current physical activity and media use on women's body image. A sample of 144 female undergraduate students completed measures of current physical activity, media use and body image, as well as providing retrospective reports of their physical activity participation and media usage during childhood and adolescence. Regression analyses showed that childhood experiences of physical activity and media use predicted adult body-image concerns more strongly than current activities. It was concluded that early experiences of both physical activity and media use during childhood and adolescence play an important role in the development of adult women's body image.
Using guided debates to teach current issues.
Hanna, Debra R
2014-06-01
A guided-debate strategy was developed for a graduate-level core course in current issues based on the Jesuit method of discernment (group decision making). The strategy encourages students to use up-to-date Internet sources to determine the range of opinions on current controversies in the discipline. In addition to providing a structured process to engage in persuasive discussion of difficult issues, the strategy facilitates critical thinking about the quality of the debate itself. Thus, students learn to avoid the pitfalls associated with consensus, such as failing to express reservations or negative opinions that might be important, while learning how to express concerns that might not be easily received by others in a group. Copyright 2014, SLACK Incorporated.
A current-carrying coil design with improved liquid cooling arrangement
NASA Astrophysics Data System (ADS)
Ricci, Leonardo; Martini, Luca Matteo; Franchi, Matteo; Bertoldi, Andrea
2013-06-01
The design of an electromagnet requires the compliance with a number of constraints such as power supply characteristics, coil inductance and resistance, and, above all, heat dissipation, which poses the limit to the maximum achievable magnetic field. A common solution consists in using copper tubes in which a coolant flows. This approach, however, introduces further hydrodynamic concerns. To overcome these difficulties, we developed a new kind of electromagnet in which the pipe concept is replaced by a duct formed by the windings. Here we report on the realization and characterization of a compact model system in which the conductors carry a current that is one order of magnitude higher than the current allowable with conventional designs.
A question of balance: nutrition, health and gastronomy.
Coveney, J; Santich, B
1997-06-01
Given the higher proportion of manufactured foods now available which meet current dietary recommendations, the food supply in developed countries like Australia could be said to be "healthier". Yet the "health" of the diet is often achieved at the expense of the "health" of the environment since ecological problems created a current food production and distribution methods remain unaddressed. Further, nutritional modifications which produce foods that are low in fat, sugar, salt and high in fibre do not necessarily address the concerns consumers have about the food supply. An emphasis solely on the physical health of populations, through improved diet, is out of keeping with current views on health which recognise the importance of overall well-being. Through the development of the concept of "sustaining gastronomy", consumers, food manufacturers and producers, and food regulators can better address the problems inherent in the food system, including those of an environmental nature.
Future land-use related water demand in California
Wilson, Tamara; Sleeter, Benjamin M.; Cameron, D. Richard
2016-01-01
Water shortages in California are a growing concern amidst ongoing drought, earlier spring snowmelt, projected future climate warming, and currently mandated water use restrictions. Increases in population and land use in coming decades will place additional pressure on already limited available water supplies. We used a state-and-transition simulation model to project future changes in developed (municipal and industrial) and agricultural land use to estimate associated water use demand from 2012 to 2062. Under current efficiency rates, total water use was projected to increase 1.8 billion cubic meters(+4.1%) driven primarily by urbanization and shifts to more water intensive crops. Only if currently mandated 25% reductions in municipal water use are continuously implemented would water demand in 2062 balance to water use levels in 2012. This is the first modeling effort of its kind to examine regional land-use related water demand incorporating historical trends of both developed and agricultural land uses.
Horcajada, Juan Pablo; Torre-Cisneros, Julián; Peña, Carmen; Fariñas, María Carmen
2014-12-01
The emergence and spread of carbapenemase-producing Enterobacteriaceae is an important and very concerning problem. There is an urgent need of new antibimicrobials for treating these infections. Currently there are some options in the pipeline. Several new beta-lactamase and carbapenemase inhibitors as avibactam and MK-7655, combined with old or new betalactams are a very interesting option. Some combinations as ceftazidime-avibactam are in the late stages of clinical development and could reach the market in the next years. New aminoglycosides as plazomicin, tetracycline derivates as eravacycline, and several other new molecules as monosulfactams are currently in different stages of development. Copyright © 2014 Elsevier España, S.L.U. All rights reserved.
Distributed-current-feed and distributed-energy-store railguns
NASA Astrophysics Data System (ADS)
Holland, L. D.
1984-03-01
In connection with advances in railgun technology evolution toward the development of systems for specific applications, investigations are being conducted regarding a wide variety of power supply and railgun systems. The present study is concerned with the development of the distributed railguns and the introduction of a new type of railgun system specifically designed for applications requiring long accelerators. It is found that the distributed railguns offer a solution to the limits on performance of the breech-fed railguns as the length of the rails becomes large. Attention is given to the pulse-forming network and breech-fed railgun, the breech-fed railgun with parallel pulse-forming network, a distributed-energy-store railgun, a distributed-current-feed (DCF) railgun, and a DCF railgun launcher.
Academic Patents and Access to Medicines in Developing Countries
2009-01-01
There is a widespread and growing concern that patents hinder access to life-saving drugs in developing countries. Recent student movements and legislative initiatives emphasize the potential role that research universities in developed countries could have in ameliorating this “access gap.” These efforts are based on the assumption that universities own patents on a substantial number of drugs and that patents on these drugs are currently filed in developing countries. I provide empirical evidence regarding these issues and explore the feasibility and desirability of proposals to change university patenting and licensing practices to promote access to medicines in the developing world. PMID:19008514
Staebler, Suzanne; Campbell, Jane; Cornelius, Patsy; Fallin-Bennett, Amanda; Fry-Bowers, Eileen; Kung, Ying Mai; LaFevers, David; Miller, Janice
To better understand policy/advocacy concepts and methodology utilized in all levels of nursing educational programs and develop clarity concerning structure of policy content and integration across all levels of education. Cross-sectional analysis of data obtained from a survey sent to 19,043 nursing faculty in the United States; 598 total responses; 514 complete responses. Quantitative data points were analyzed using SPSS and qualitative data was grouped and analyzed by theme. Barriers and perceptions of student engagement and student learning outcomes along with institutional and faculty development barriers were explored in baccalaureate, masters, and doctoral level nursing programs. Thirty-six percent of respondents reported having experience in development and implementation of policy, ranging from local to international spheres and 21% reported active involvement in current state and federal policy development. Seventy percent of respondents have advocated for the nursing profession through professional organizations while 44% report current activity in legislative advocacy. The value of nursing policy education, advocacy, and analysis must be valued in higher education. Copyright © 2017 Elsevier Inc. All rights reserved.
NASA Technical Reports Server (NTRS)
Nessler, Phillip J., Jr.
1998-01-01
The subject of outdoor use of lasers relative to air traffic has become a diverse and dynamic topic. During the past several decades, the use of lasers in outdoor research activities have increased significantly. Increases in the outdoor use of lasers and increases in air traffic densities have changed the levels of risk involved. To date there have been no documented incidents of air traffic interference from research lasers; however, incidents involving display lasers have shown a marked increase. As a result of the national response to these incidents, new concerns over lasers have arisen. Through the efforts of the SAE G-10T Laser Safety Hazards Subcommittee and the ANSI Z136.6 development committee, potential detrimental effects to air traffic beyond the traditional eye damage concerns have been identified. An increased emphasis from the Federal Aviation Administration (FAA), the Center for Devices and Radiological Hazards (CDRH), and the National Transportation Safety Board (NTSB) along with increased concern by the public have resulted in focused scrutiny of potential hazards presented by lasers. The research community needs to rethink the traditional methods of risk evaluation and application of protective measures. The best current approach to assure adequate protection of air traffic is the application of viable hazard and risk analysis and the use of validated protective measures. Standards making efforts and regulatory development must be supported by the research community to assure that reasonable measures are developed. Without input, standards and regulations can be developed that are not compatible with the needs of the research community. Finally, support is needed for the continued development and validation of protective measures.
Predicted aircraft effects on stratospheric ozone
NASA Technical Reports Server (NTRS)
Ko, Malcolm K. W.; Wofsy, Steve; Kley, Dieter; Zhadin, Evgeny A.; Johnson, Colin; Weisenstein, Debra; Prather, Michael J.; Wuebbles, Donald J.
1991-01-01
The possibility that the current fleet of subsonic aircraft may already have caused detectable changes in both the troposphere and stratosphere has raised concerns about the impact of such operations on stratospheric ozone and climate. Recent interest in the operation of supersonic aircraft in the lower stratosphere has heightened such concerns. Previous assessments of impacts from proposed supersonic aircraft were based mostly on one-dimensional model results although a limited number of multidimensional models were used. In the past 15 years, our understanding of the processes that control the atmospheric concentrations of trace gases has changed dramatically. This better understanding was achieved through accumulation of kinetic data and field observations as well as development of new models. It would be beneficial to start examining the impact of subsonic aircraft to identify opportunities to study and validate the mechanisms that were proposed to explain the ozone responses. The two major concerns are the potential for a decrease in the column abundance of ozone leading to an increase in ultraviolet radiation at the ground, and redistribution of ozone in the lower stratosphere and upper troposphere leading to changes in the Earth's climate. Two-dimensional models were used extensively for ozone assessment studies, with a focus on responses to chlorine perturbations. There are problems specific to the aircraft issues that are not adequately addressed by the current models. This chapter reviews the current status of the research on aircraft impact on ozone with emphasis on immediate model improvements necessary for extending our understanding. The discussion will be limited to current and projected commercial aircraft that are equipped with air-breathing engines using conventional jet fuel. The impacts are discussed in terms of the anticipated fuel use at cruise altitude.
EMERGING ENVIRONMENTAL CONTAMINANTS AND CURRENT ISSUES, MEETING IN SEATTLE, WA
Much has been achieved in the way of environmental protection over the last 30 years. However, as we learn more, new concerns arise. This presentation will discuss chemical and microbial contaminants that the U.S. EPA and other agencies are currently concerned about. In this gr...
DOE Office of Scientific and Technical Information (OSTI.GOV)
Marshall, Rachael E., E-mail: rmarsh01@uoguelph.ca; Farahbakhsh, Khosrow, E-mail: khosrowf@uoguelph.ca
Highlights: ► Five drivers led developed countries to current solid waste management paradigm. ► Many unique factors challenge developing country solid waste management. ► Limited transferability of developed country approaches to developing countries. ► High uncertainties and decision stakes call for post-normal approaches. ► Systems thinking needed for multi-scale, self-organizing eco-social waste systems. - Abstract: Solid waste management (SWM) has become an issue of increasing global concern as urban populations continue to rise and consumption patterns change. The health and environmental implications associated with SWM are mounting in urgency, particularly in the context of developing countries. While systems analyses largelymore » targeting well-defined, engineered systems have been used to help SWM agencies in industrialized countries since the 1960s, collection and removal dominate the SWM sector in developing countries. This review contrasts the history and current paradigms of SWM practices and policies in industrialized countries with the current challenges and complexities faced in developing country SWM. In industrialized countries, public health, environment, resource scarcity, climate change, and public awareness and participation have acted as SWM drivers towards the current paradigm of integrated SWM. However, urbanization, inequality, and economic growth; cultural and socio-economic aspects; policy, governance, and institutional issues; and international influences have complicated SWM in developing countries. This has limited the applicability of approaches that were successful along the SWM development trajectories of industrialized countries. This review demonstrates the importance of founding new SWM approaches for developing country contexts in post-normal science and complex, adaptive systems thinking.« less
NASA Technical Reports Server (NTRS)
Sun, Yushi; Sun, Changhong; Zhu, Harry; Wincheski, Buzz
2006-01-01
Stress corrosion cracking in the relief radius area of a space shuttle primary reaction control thruster is an issue of concern. The current approach for monitoring of potential crack growth is nondestructive inspection (NDI) of remaining thickness (RT) to the acoustic cavities using an eddy current or remote field eddy current probe. EDM manufacturers have difficulty in providing accurate RT calibration standards. Significant error in the RT values of NDI calibration standards could lead to a mistaken judgment of cracking condition of a thruster under inspection. A tool based on eddy current principle has been developed to measure the RT at each acoustic cavity of a calibration standard in order to validate that the standard meets the sample design criteria.
Faculty application of the American Psychological Association style.
Morse, Gwen Goetz
2009-10-01
This article explores current faculty methods with the application and evaluation of the American Psychological Association (APA) style. Specific aims were to determine concerns related to APA style, review faculty grading practices, identify institutional resources, and report potential solutions for improving application of APA style. A survey with an exploratory descriptive research design was developed and distributed online to academic chairs and deans, requesting their support in distributing the survey to their faculty. Responses (N = 704) were grouped into five categories: departmental and personal concerns; faculty grading practices; institutional resources; format, writing style, and grammar; and suggestions and potential solutions. Sixty percent reported that application and evaluation of APA style is a concern in their department. Content analysis identified four categories as proposed solutions: consistency, education, resources, and dialogue. On the basis of the feedback of the participants, the CRED program is proposed for the issues that were identified. Copyright 2009, SLACK Incorporated.
Space mechanisms needs for future NASA long duration space missions
NASA Technical Reports Server (NTRS)
Fusaro, Robert L.
1991-01-01
Future NASA long duration missions will require high performance, reliable, long lived mechanical moving systems. In order to develop these systems, high technology components, such as bearings, gears, seals, lubricants, etc., will need to be utilized. There has been concern in the NASA community that the current technology level in these mechanical component/tribology areas may not be adequate to meet the goals of long duration NASA mission such as Space Exploration Initiative (SEI). To resolve this concern, NASA-Lewis sent a questionnaire to government and industry workers (who have been involved in space mechanism research, design, and implementation) to ask their opinion if the current space mechanisms technology (mechanical components/tribology) is adequate to meet future NASA Mission needs and goals. In addition, a working group consisting of members from each NASA Center, DoD, and DOE was established to study the technology status. The results of the survey and conclusions of the working group are summarized.
Bioethics for human geneticists: models for reasoning and methods for teaching.
Parker, L. S.
1994-01-01
The ethical issues raised by the Human Genome Project (HGP) and by human genetics in general are not entirely novel. In fact, the ethical issues surrounding genetic research and the provision of genetic services fit into the evolution of bioethics, a field of inquiry which has its roots in concerns of the 1970s, concerns about the dignity and self-determination of individuals and about the development of medical technologies. Although bioethics has been largely occupied with patient-centered concerns, attention is currently shifting toward socially oriented issues, such as the justice of the existing health-care system. Genetic counseling has already incorporated many of the lessons of early bioethics and, as a profession, adheres to a consultand-centered ethic which reflects the values incorporated into the doctrine of informed consent, which is a cornerstone of bioethics. The mandate of the Ethical, Legal, and Social Implications Program of the HGP--to anticipate ethical problems arising from advances in genetics and to educate the public about genetics--reflects not only the nonpaternalistic approach of early bioethics but also bioethics' increasing attention to the ethical import of systemic and institutional factors, as well as an anticipatory and preventive approach to dealing with ethical concerns. Because bioethics has so much to contribute to current consideration of ethical issues in human genetics, it is important to provide training in ethics to those working in the field. Guidelines for using a case-oriented approach are suggested. PMID:8279464
Licensed pertussis vaccines in the United States. History and current state.
Klein, Nicola P
2014-01-01
The United States switched from whole cell to acellular pertussis vaccines in the 1990s following global concerns with the safety of the whole cell vaccines. Despite high levels of acellular pertussis vaccine coverage, the United States and other countries are experiencing large pertussis outbreaks. The aim of this article is to describe the historical context which led to acellular pertussis vaccine development, focusing on vaccines currently licensed in the US, and to review evidence that waning protection following licensed acellular pertussis vaccines have been significant factors in the widespread reappearance of pertussis.
A platform for evolving intelligently interactive adversaries.
Fogel, David B; Hays, Timothy J; Johnson, Douglas R
2006-07-01
Entertainment software developers face significant challenges in designing games with broad appeal. One of the challenges concerns creating nonplayer (computer-controlled) characters that can adapt their behavior in light of the current and prospective situation, possibly emulating human behaviors. This adaptation should be inherently novel, unrepeatable, yet within the bounds of realism. Evolutionary algorithms provide a suitable method for generating such behaviors. This paper provides background on the entertainment software industry, and details a prior and current effort to create a platform for evolving nonplayer characters with genetic and behavioral traits within a World War I combat flight simulator.
Silver in medicine: a brief history BC 335 to present.
Barillo, David J; Marx, David E
2014-12-01
Silver is a naturally occurring element. Similar to other metals, the ionized form of silver (Ag(+1)) has known antimicrobial properties. A number of wound dressings incorporating silver ion or silver compounds have recently been developed and marketed. In addition, the antimicrobial effects of silver are currently being promoted in consumer products such as clothing and household appliances. The present use of silver in medical and consumer products has prompted concerns for potential toxicity and ecological effects, including induction of microbial resistance to antibiotics. These concerns ignore the fact that silver has been used for medicinal purposes for several thousand years. A historical review of the uses of silver in medicine is presented.
Acute stress responses: A review and synthesis of ASD, ASR, and CSR.
Isserlin, Leanna; Zerach, Gadi; Solomon, Zahava
2008-10-01
Toward the development of a unifying diagnosis for acute stress responses this article attempts to find a place for combat stress reaction (CSR) within the spectrum of other defined acute stress responses. This article critically compares the diagnostic criteria of acute stress disorder (ASD), acute stress reaction (ASR), and CSR. Prospective studies concerning the predictive value of ASD, ASR, and CSR are reviewed. Questions, recommendations, and implications for clinical practice are raised concerning the completeness of the current acute stress response diagnoses, the heterogeneity of different stressors, the scope of expected outcomes, and the importance of decline in function as an indicator of future psychological, psychiatric, and somatic distress. PsycINFO Database Record 2009 APA.
Answering Public Health Concerns Over Japanese Nuclear Disaster | ORAU
DOE Office of Scientific and Technical Information (OSTI.GOV)
Allen, Leeanna; Vasconez, Rachel
When the Fukushima Daiichi Nuclear Power Plant became crippled following Japan's March 2011 earthquake and tsunami, some U.S. citizens became concerned about whether radiation would disperse across the Pacific Ocean. As the Centers for Disease Control and Prevention prepared to assist in the U.S. response effort, ORAU provided the CDC with onsite, staff support at its Joint Information Center. ORAU also had a lead role in the development and execution of the CDC's first-ever Bridging the Gaps: Public Health and Radiation Emergency Preparedness conference, which took place 10 days after the earthquake and served as a forum for discussing themore » current state of radiation emergency preparedness.« less
Environmental study of ERTS-1 imagery: Lake Champlain and Vermont
NASA Technical Reports Server (NTRS)
Lind, A. O.; Henson, E. B.; Pelton, J. O.
1973-01-01
Environmental concerns of the State of Vermont currently being stressed include water quality in Lake Champlain and a state-wide land use and capability plan. Significant results obtained from ERTS-1 relate directly to the above concerns. Industrial water pollution and turbidity in Lake Champlain have been identified and mapped and the ERTS pollution data will be used in the developing court suit which Vermont has initiated against the polluters. ERTS imagery has also provided a foundation for updating and revising land use inventories. Major classes of land use have been identified and mapped, and substantial progress has been made toward the mapping of such land use divisions as crop and forest type, and wetlands.
Comprehensive Nuclear-Test-Ban Treaty: Background and Current Developments
2013-01-02
41 The National Academy of Sciences Study and Its Critics ...reliable and safe. So he has not ruled out testing in the future, but there are no plans to do so.”6 Critics expressed concern about the...nuclear weapons testing.”7 Another critic felt that increased funding for test readiness would in effect give prior approval for testing. In July 2002 a
ERIC Educational Resources Information Center
Schlaen, Norah
This analytical bibliography describes a group of selected documents that examine the current status and extent of development of adult education in Latin America. Documents were selected for inclusion based upon their focus on and concern for international and national goals and needs of adult education programs and for distribution to countries…
ERIC Educational Resources Information Center
Cheng, Doris Pui-Wah
2012-01-01
For centuries, educators and psychologists have advocated "play" as the ideal activity for the development of young children. Actually, play has been found currently to be the central pedagogy in the learning of young children in 21 countries in the world. However, the quality of play-based pedagogy is becoming a key concern across…
ERIC Educational Resources Information Center
Branscome, Eric E.
2012-01-01
President Obama recently described America's current economic, societal, educational, and technological circumstances as "our generation's 'Sputnik' moment." If history repeats itself in the twenty-first century, music educators may face a situation similar to that which developed in the 1960s concerning the impact of education reform on…
International nuclear fuel cycle fact book. Revision 6
DOE Office of Scientific and Technical Information (OSTI.GOV)
Harmon, K.M.; Lakey, L.T.; Leigh, I.W.
1986-01-01
The International Fuel Cycle Fact Book has been compiled in an effort to provide (1) an overview of worldwide nuclear power and fuel cycle programs and (2) current data concerning fuel cycle and waste management facilities, R and D programs and key personnel. Additional information on each country's program is available in the International Source Book: Nuclear Fuel Cycle Research and Development, PNL-2478, Rev. 2.
ERIC Educational Resources Information Center
FengLiang, Li; Morgan, W. John
2008-01-01
The development of private higher education in China is an important area of policy concern and for academic research, especially under the conditions of globalization. This article reviews the current situation and forecasts the likely trend in several key areas, such as governmental regulation, funds and competition for enrolments. The article…
[Three centuries with the Fleet (to the 300th anniversary of the Saint-Petersburg naval hospital)].
Buzov, E Ya; Kasatkin, V I; Makarenko, B G; Shilov, S A
2015-09-01
The authors analysed the history of the Saint-Petersburg naval hospital, founded in October, 1715 by Peter the Great, defined its role in the key historical events during organisation of medical, aid delivery to wounded and patients, discussed current tasks, concerning development of hospital art when forming modern image of the navy of the Russian Federation.
ERIC Educational Resources Information Center
Martínez, Anabella; Borjas, Mónica; Herrera, Mariela; Valencia, Jorge
2015-01-01
Undergraduate student attrition is a major concern in higher education. It is usually explained by the impact of student attributes; however, recent developments in student success literature point to the need of exploring institutional practices that may impact a student's decision to abandon their studies. The current weight of academic quality…
ERIC Educational Resources Information Center
Odumuh, Adama Emmanuel
A discussion of the current state of education in Nigeria looks at two systems of education introduced in different post-colonial administrations (universal primary education and the 6/3/3/4-year scheme) and examines language policy in education, particularly the provisions concerning use of native language as the medium of instruction under the…
ERIC Educational Resources Information Center
Baxter, Susan; Enderby, Pam; Evans, Philippa; Judge, Simon
2012-01-01
Background: There has been a rapid growth in recent years of available technologies for individuals with communication difficulties. Research in the area is currently underdeveloped with practitioners having a limited body of work on which to draw to guide the process of intervention. Concerns have been raised that this newly developed technology…
Towards a For-Profit University in Dublin: Another Brick in the Wall of Neo-Liberalism?
ERIC Educational Resources Information Center
Limond, David
2010-01-01
This article concerns the provision of for-profit higher education in the Republic of Ireland (RoI), particularly in Dublin. It briefly sketches the general development of university/college provision in the RoI and, more importantly, it describes certain aspects of the current state of play and makes a tentative prediction for the future--namely,…
Nishiura, Hiroshi; Imai, Hirohisa; Nakao, Hiroyuki; Tsukino, Hiromasa; Kuroda, Yoshiki; Katoh, Takahiko
2002-11-01
Current and future trends regarding genetically modified (GM) crops and food stuffs were reviewed, with a particular focus on public acceptance and safety assessment. While GM foods, foods derived from biotechnology, are popular with growers and producers, they are still a matter of some concern among consumers. In fact, our recent surveys showed that Japanese consumers had become uneasy about the potential health risks of genetically modified foods. Many Japanese consumers have only vague ideas about the actual health risks, and they appear to be making decisions simply by rejecting GM food because of non-informed doubts. Although the debate about GM foods has increased in the mass media and scientific journals, few articles concerning direct studies on the potential toxicity or adverse health effects of GM foods have appeared. The roles of relevant international regulatory bodies in ensuring that GM crops and food are safe are therefore have summarized. Finally, the current debate on use of GM crops in agriculture and future trends for development of GM foods with enriched nutrients, better functionality, and medicinal ingredients, which will be of direct benefit to the consumer, are covered.
Developmental Neurotoxicants in E-Waste: An Emerging Health Concern
Chen, Aimin; Dietrich, Kim N.; Huo, Xia; Ho, Shuk-mei
2011-01-01
Objective Electronic waste (e-waste) has been an emerging environmental health issue in both developed and developing countries, but its current management practice may result in unintended developmental neurotoxicity in vulnerable populations. To provide updated information about the scope of the issue, presence of known and suspected neurotoxicants, toxicologic mechanisms, and current data gaps, we conducted this literature review. Data sources We reviewed original articles and review papers in PubMed and Web of Science regarding e-waste toxicants and their potential developmental neurotoxicity. We also searched published reports of intergovernmental and governmental agencies and nongovernmental organizations on e-waste production and management practice. Data extraction We focused on the potential exposure to e-waste toxicants in vulnerable populations—that is, pregnant women and developing children—and neurodevelopmental outcomes. In addition, we summarize experimental evidence of developmental neurotoxicity and mechanisms. Data synthesis In developing countries where most informal and primitive e-waste recycling occurs, environmental exposure to lead, cadmium, chromium, polybrominated diphenyl ethers, polychlorinated biphenyls, and polycyclic aromatic hydrocarbons is prevalent at high concentrations in pregnant women and young children. Developmental neurotoxicity is a serious concern in these regions, but human studies of adverse effects and potential mechanisms are scarce. The unprecedented mixture of exposure to heavy metals and persistent organic pollutants warrants further studies and necessitates effective pollution control measures. Conclusions Pregnant women and young children living close to informal e-waste recycling sites are at risk of possible perturbations of fetus and child neurodevelopment. PMID:21081302
Overview of current capabilities and research and technology developments for planetary protection
NASA Astrophysics Data System (ADS)
Frick, Andreas; Mogul, Rakesh; Stabekis, Pericles; Conley, Catharine A.; Ehrenfreund, Pascale
2014-07-01
The pace of scientific exploration of our solar system provides ever-increasing insights into potentially habitable environments, and associated concerns for their contamination by Earth organisms. Biological and organic-chemical contamination has been extensively considered by the COSPAR Panel on Planetary Protection (PPP) and has resulted in the internationally recognized regulations to which spacefaring nations adhere, and which have been in place for 40 years. The only successful Mars lander missions with system-level “sterilization” were the Viking landers in the 1970s. Since then different cleanliness requirements have been applied to spacecraft based on their destination, mission type, and scientific objectives. The Planetary Protection Subcommittee of the NASA Advisory Council has noted that a strategic Research & Technology Development (R&TD) roadmap would be very beneficial to encourage the timely availability of effective tools and methodologies to implement planetary protection requirements. New research avenues in planetary protection for ambitious future exploration missions can best be served by developing an over-arching program that integrates capability-driven developments with mission-driven implementation efforts. This paper analyzes the current status concerning microbial reduction and cleaning methods, recontamination control and bio-barriers, operational analysis methods, and addresses concepts for human exploration. Crosscutting research and support activities are discussed and a rationale for a Strategic Planetary Protection R&TD Roadmap is outlined. Such a roadmap for planetary protection provides a forum for strategic planning and will help to enable the next phases of solar system exploration.
Shepherd, Jennifer H; Screen, Hazel R C
2013-01-01
Tendon injuries, often called tendinopathies, are debilitating and painful conditions, generally considered to develop as a result of tendon overuse. The aetiology of tendinopathy remains poorly understood, and whilst tendon biopsies have provided some information concerning tendon appearance in late-stage disease, there is still little information concerning the mechanical and cellular events associated with disease initiation and progression. Investigating this in situ is challenging, and numerous models have been developed to investigate how overuse may generate tendon fatigue damage and how this may relate to tendinopathy conditions. This article aims to review these models and our current understanding of tendon fatigue damage. We review the strengths and limitations of different methodologies for characterizing tendon fatigue, considering in vitro methods that adopt both viable and non-viable samples, as well as the range of different in vivo approaches. By comparing data across model systems, we review the current understanding of fatigue damage development. Additionally, we compare these findings with data from tendinopathic tissue biopsies to provide some insights into how these models may relate to the aetiology of tendinopathy. Fatigue-induced damage consistently highlights the same microstructural, biological and mechanical changes to the tendon across all model systems and also correlates well with the findings from tendinopathic biopsy tissue. The multiple testing routes support matrix damage as an important contributor to tendinopathic conditions, but cellular responses to fatigue appear complex and often contradictory. PMID:23837793
Kwan, Mun Yee; Gordon, Kathryn H; Minnich, Allison M
2018-01-01
Empirical evidence suggests the importance of considering acculturative stress and perceived discrimination in understanding the mental health of ethnic minority groups, including their eating behaviors and associated psychopathology. The current study examined the effect of acculturative stress and perceived discrimination on eating disorder symptoms among ethnic minority undergraduate students. A total of 187 ethnic minority undergraduate students (41.2% men) completed this cross-sectional study by completing self-report questionnaires on a secure online system. Regression analyses revealed a main effect of acculturative stress on eating concern, shape concern, weight concern, drive for thinness, and bulimia but not restraint or body dissatisfaction. Gender moderated the effect of acculturative stress on drive for muscularity, suggesting that this effect was only significant in women, but not men. The main effect of perceived discrimination was significant for restraint, eating concern, shape concern, weight concern, and drive for muscularity but not drive for thinness, bulimia, or body dissatisfaction. Acculturative stress and perceived discrimination are important factors to consider in understanding the development and maintenance of eating disorder symptoms among ethnic minority populations. Targeting these two factors may improve the effectiveness of intervention programs for eating disorder symptoms among ethnic minority undergraduate students. Copyright © 2018 Elsevier Ltd. All rights reserved.
Children and computers: new technology--old concerns.
Wartella, E A; Jennings, N
2000-01-01
Computer technology has ushered in a new era of mass media, bringing with it great promise and great concerns about the effect on children's development and well-being. Although we tend to see these issues as being new, similar promises and concerns have accompanied each new wave of media technology throughout the past century: films in the early 1900s, radio in the 1920s, and television in the 1940s. With the introduction of each of these technologies, proponents touted the educational benefits for children, while opponents voiced fears about exposure to inappropriate commercial, sexual, and violent content. This article places current studies on children and computers in a historical context, noting the recurrent themes and patterns in media research during the twentieth century. Initial research concerning each innovation has tended to focus on issues of access and the amount of time children were spending with the new medium. As use of the technology became more prevalent, research shifted to issues related to content and its effects on children. Current research on children's use of computers is again following this pattern. But the increased level of interactivity now possible with computer games and with the communication features of the Internet has heightened both the promise of greatly enriched learning and the concerns related to increased risk of harm. As a result, research on the effects of exposure to various types of content has taken on a new sense of urgency. The authors conclude that to help inform and sustain the creation of more quality content for children, further research is needed on the effects of media on children, and new partnerships must be forged between industry, academia, and advocacy groups.
Koh, Liling; Glaetzer, Christoph; Chuen Li, Shu; Zhang, Meng
2016-05-01
China is investing considerably in health care reforms to address issues in its health care system. An example is access to innovative drugs, which remains challenging because it is largely dependent on patient self-pay. Recognizing this, the government has invested considerably in its basic medical insurance. As health care expenditure increases, there are growing concerns on budget control. Several health policy tools have been discussed recently such as health technology assessment, international reference pricing, and hospital budget control tools, which can be viewed as addressing the affordability concerns of the government budget. China has also listed her health outcomes goals in "Healthy China 2020" initiative. This article aimed to discuss the "fit-for-purpose" of these tools to address budget concerns and support China in reaching her health outcomes goals. The findings are informed by a panel discussion at ISPOR Asia Pacific 2014, literature review, and authors' experience. This review looks at the current developments in China and the considerations and implications for using these tools by drawing experiences from countries where they are used. These tools are generally used in countries with advanced health care systems. China's health care spending is still below that of countries with advanced health care systems and below World Health Organization recommendation. China has not yet reached the "critical mass" necessary for the effective use of these tools. As China continues its health care reforms, increase in health care spending to balance the health needs of the population would be key. Copyright © 2015. Published by Elsevier Inc.
NASA Technical Reports Server (NTRS)
Sheth, Rubik B.; Stephan, Ryan A.; Hawkins-Reynolds Ebony
2011-01-01
Liquid/Liquid Heat Exchangers (L/L HX) are an integral portion of any spacecraft active thermal control system. For this study the X-38 L/L HX was used as a baseline. As detailed in a previous ICES manuscript, NASA paired with Pacific Northwest National Laboratory to develop a Microchannel L/L HX (MHX). This microchannel HX was designed to meet the same performance characteristics as the aforementioned X-38 HX. The as designed Microchannel HX has a 26% and 60% reduction in mass and volume, respectively. Due to the inherently smaller flow passages the design team was concerned about fouling affecting performance during extended missions. To address this concern, NASA has developed a test stand and is currently performing an 18 month life test on the MHX. This report will detail the up-to-date performance of the MHX during life testing.
Mlyniec, Wallace J
2010-01-01
The Convention on the Rights of the Child (CRC) guarantees that children accused of crimes will have the right to fair court procedures and humane sentences. Current U.S. laws concerning the child's age when a court has jurisdiction, and others concerning sentencing practices and the place of confinement, contravene the provisions of the CRC. Some U.S. laws are consistent with the treaty but are nonetheless not enforced. Recent developments, including increasing understanding of brain development, U.S. Supreme Court decisions on the constitutionality of punishments for children, and the Committee on the Rights of the Child General Comment 10, will have substantial impacts on U.S. ratification. This article discusses Articles 37 and 40 of the CRC and their effect on U.S. practices if the treaty is ratified.
[Therapeutic use of hematopoietic growth factors. II. GM-CSF and G-CSF].
Royer, B; Arock, M
1998-01-01
The second part of this review on haematopoietic growth factors is focused on the therapeutic use of GM-CSF and G-CSF. Such therapeutic applications have raised very great hopes for clinical haematology. However, it should not be forgotten that these haematopoietic growth factors, which are very costly, are powerful two-edged weapons capable of triggering a cascade of reactions, and have a field of activity that often goes beyond the single highly specific property which it is hoped they possess. The risks and costs of their use are currently being evaluated. Waited developments concerning these molecules focus on three axes: a best use of factors already commercialized, especially concerning adaptation of posologies and new indications, the development of hybrid molecules from already known haematopoietic growth factors, possessing the advantages of respective factors, but not their disadvantages, the discovery of new haematopoietic growth factors with potential therapeutic application.
Regulation of stem cell-based therapies in Canada: current issues and concerns.
von Tigerstrom, Barbara; Nguyen, Thu Minh; Knoppers, Bartha Maria
2012-09-01
Stem cell therapies offer enormous potential for the treatment of a wide range of diseases and conditions. Despite the excitement over such advances, regulators are faced with the challenge of determining criteria to ensure stem cells and their products are safe and effective for human use. However, stem cell-based products and therapies present unique regulatory challenges because standard drug development models do not wholly apply given the complexity and diversity of these products and therapies. As a result, regulatory requirements are often unclear and ambiguous creating unnecessary barriers for research. In order to better understand the barriers that might affect Canadian stem cell researchers, we sought feedback from stakeholders regarding areas of uncertainty or concern about existing regulatory oversight of cell therapies. A selection of Canadian researchers and clinicians working in the area of stem cell research were interviewed to assess certain key questions: 1) whether current regulatory requirements are easily accessible and well understood; 2) whether regulatory requirements create important challenges or barriers; and 3) whether there is a need for further guidance on the issue. The results of this survey are summarized and compared to issues and concerns experienced in other countries, as reported in the literature, to identify challenges which may be on the horizon and to provide possible solutions for regulatory reform.
Ongoing ethical issues concerning authorship in biomedical journals: an integrative review
Kornhaber, Rachel Anne; McLean, Loyola M; Baber, Rodney J
2015-01-01
Health professionals publishing within the field of health sciences continue to experience issues concerning appropriate authorship, which have clinical, ethical, and academic implications. This integrative review sought to explore the key issues concerning authorship from a bioethical standpoint, aiming to explore the key features of the authorship debate. Studies were identified through an electronic search, using the PubMed, Cumulative Index to Nursing and Allied Health Literature (CINAHL), and Scopus databases of peer-reviewed research, published between 2009 and 2014, limited to English language research, with search terms developed to reflect the current issues of authorship. From among the 279 papers identified, 20 research papers met the inclusion criteria. Findings were compiled and then arranged to identify themes and relationships. The review incorporated a wide range of authorship issues encompassing equal-credited authors, honorary (guest/gift) and ghost authorship, perception/experiences of authorship, and guidelines/policies. This review suggests that the International Committee of Medical Journal Editors’ (ICMJE) recommended guidelines for authorship are not reflected in current authorship practices within the domain of health sciences in both low-and high-impact-factor journals. This devaluing of the true importance of authorship has the potential to affect the validity of authorship, diminish the real contributions of the true authors, and negatively affect patient care. PMID:26257520
Ongoing ethical issues concerning authorship in biomedical journals: an integrative review.
Kornhaber, Rachel Anne; McLean, Loyola M; Baber, Rodney J
2015-01-01
Health professionals publishing within the field of health sciences continue to experience issues concerning appropriate authorship, which have clinical, ethical, and academic implications. This integrative review sought to explore the key issues concerning authorship from a bioethical standpoint, aiming to explore the key features of the authorship debate. Studies were identified through an electronic search, using the PubMed, Cumulative Index to Nursing and Allied Health Literature (CINAHL), and Scopus databases of peer-reviewed research, published between 2009 and 2014, limited to English language research, with search terms developed to reflect the current issues of authorship. From among the 279 papers identified, 20 research papers met the inclusion criteria. Findings were compiled and then arranged to identify themes and relationships. The review incorporated a wide range of authorship issues encompassing equal-credited authors, honorary (guest/gift) and ghost authorship, perception/experiences of authorship, and guidelines/policies. This review suggests that the International Committee of Medical Journal Editors' (ICMJE) recommended guidelines for authorship are not reflected in current authorship practices within the domain of health sciences in both low-and high-impact-factor journals. This devaluing of the true importance of authorship has the potential to affect the validity of authorship, diminish the real contributions of the true authors, and negatively affect patient care.
Relatives’ level of satisfaction with advanced cancer care in Greenland – a mixed methods study
Augustussen, Mikaela; Hounsgaard, Lise; Pedersen, Michael Lynge; Sjøgren, Per; Timm, Helle
2017-01-01
ABSTRACT Palliative cancer care in Greenland is provided by health professionals at local level, the national Queen Ingrid’s Hospital and at Rigshospitalet in Denmark. To improve and develop care for relatives of patients with advanced cancer, we conducted a mixed method study examining relatives’ level of satisfaction with care and treatment and their current main concerns. The aim was to investigate relatives’ level of satisfaction with advanced cancer care and bring to light their current main concerns. The FAMCARE-20 questionnaire was translated to Greenlandic and pilot tested. The questionnaire was supplemented by open-ended questions about relative’s current main concerns and analyzed with a phenomenological hermeneutical approach. Greenlandic patients with advanced cancer who were previously participating in a prospective study were asked if their closest adult relative would participate in the study. Telephone interviews were conducted and relatives responded to the questionnaire. A total of thirty-two relatives were contacted by telephone and 30 (94%) completed the FAMCARE-20 questionnaire and answered open-ended questions. The highest rate of satisfaction was with the availability of a hospital bed (66%) and relatives were the most dissatisfied with the lack of inclusion in decision making related to treatment and care (71%) and the length of time required to diagnose cancer (70%). Responses to the open-ended questions revealed that relatives faced challenges in gaining access to information from health professionals. They experienced a lack of security, worries about the future and a lack of support at home. The study showed a substantial level of dissatisfaction among relatives of patients with advanced cancer. We strongly recommend a focus on psychosocial care, more access to information and to include relatives in decision making and in the future planning of palliative care services. An assessment of relatives’ needs is essential to develop an adequate palliative care in a range of settings. PMID:28613119
Plastics, the environment and human health: current consensus and future trends
Thompson, Richard C.; Moore, Charles J.; vom Saal, Frederick S.; Swan, Shanna H.
2009-01-01
Plastics have transformed everyday life; usage is increasing and annual production is likely to exceed 300 million tonnes by 2010. In this concluding paper to the Theme Issue on Plastics, the Environment and Human Health, we synthesize current understanding of the benefits and concerns surrounding the use of plastics and look to future priorities, challenges and opportunities. It is evident that plastics bring many societal benefits and offer future technological and medical advances. However, concerns about usage and disposal are diverse and include accumulation of waste in landfills and in natural habitats, physical problems for wildlife resulting from ingestion or entanglement in plastic, the leaching of chemicals from plastic products and the potential for plastics to transfer chemicals to wildlife and humans. However, perhaps the most important overriding concern, which is implicit throughout this volume, is that our current usage is not sustainable. Around 4 per cent of world oil production is used as a feedstock to make plastics and a similar amount is used as energy in the process. Yet over a third of current production is used to make items of packaging, which are then rapidly discarded. Given our declining reserves of fossil fuels, and finite capacity for disposal of waste to landfill, this linear use of hydrocarbons, via packaging and other short-lived applications of plastic, is simply not sustainable. There are solutions, including material reduction, design for end-of-life recyclability, increased recycling capacity, development of bio-based feedstocks, strategies to reduce littering, the application of green chemistry life-cycle analyses and revised risk assessment approaches. Such measures will be most effective through the combined actions of the public, industry, scientists and policymakers. There is some urgency, as the quantity of plastics produced in the first 10 years of the current century is likely to approach the quantity produced in the entire century that preceded. PMID:19528062
Plastics, the environment and human health: current consensus and future trends.
Thompson, Richard C; Moore, Charles J; vom Saal, Frederick S; Swan, Shanna H
2009-07-27
Plastics have transformed everyday life; usage is increasing and annual production is likely to exceed 300 million tonnes by 2010. In this concluding paper to the Theme Issue on Plastics, the Environment and Human Health, we synthesize current understanding of the benefits and concerns surrounding the use of plastics and look to future priorities, challenges and opportunities. It is evident that plastics bring many societal benefits and offer future technological and medical advances. However, concerns about usage and disposal are diverse and include accumulation of waste in landfills and in natural habitats, physical problems for wildlife resulting from ingestion or entanglement in plastic, the leaching of chemicals from plastic products and the potential for plastics to transfer chemicals to wildlife and humans. However, perhaps the most important overriding concern, which is implicit throughout this volume, is that our current usage is not sustainable. Around 4 per cent of world oil production is used as a feedstock to make plastics and a similar amount is used as energy in the process. Yet over a third of current production is used to make items of packaging, which are then rapidly discarded. Given our declining reserves of fossil fuels, and finite capacity for disposal of waste to landfill, this linear use of hydrocarbons, via packaging and other short-lived applications of plastic, is simply not sustainable. There are solutions, including material reduction, design for end-of-life recyclability, increased recycling capacity, development of bio-based feedstocks, strategies to reduce littering, the application of green chemistry life-cycle analyses and revised risk assessment approaches. Such measures will be most effective through the combined actions of the public, industry, scientists and policymakers. There is some urgency, as the quantity of plastics produced in the first 10 years of the current century is likely to approach the quantity produced in the entire century that preceded.
Incentives for organ donation in the United States: feasible alternative or forthcoming apocalypse?
Hippen, Benjamin; Matas, Arthur
2009-04-01
Several factors have generated interest in proposals to offer incentives in exchange for kidneys from living donors, including the growing shortage of available organs, the apparent asymptote of traditional means of organ procurement, and the intimate link between the inadequacies of organ procurement policies in developed countries with the flourishing of underground organ trafficking in developing countries. Herein, we review the scope and dimensions of the growing shortage of organs in the United States, with attention to how each of the proposed solutions to same has proven insufficient. With special attention to the concerns leveled by Gabriel Danovitch in his 'Open Letter,' we conclude that each of his concerns are unfounded, and offer a prospectus on how a trial of such systems might be pursued in the United States. The failure of current approaches to organ procurement in the United States and other developed countries has led to unnecessary suffering and death, with morally unacceptable consequences for developing countries. For these reasons, a structured trial of incentives for organ procurement in the United States is a moral imperative.
Challenges in the clinical development of new antiepileptic drugs.
Franco, Valentina; French, Jacqueline A; Perucca, Emilio
2016-01-01
Despite the current availability in the market of over two dozen antiepileptic drugs (AEDs), about one third of people with epilepsy fail to achieve complete freedom from seizures with existing medications. Moreover, currently available AEDs have significant limitations in terms of safety, tolerability and propensity to cause or be a target for clinically important adverse drug interactions. A review of the evidence shows that there are many misperceptions about the viability of investing into new therapies for epilepsy. In fact, there are clear incentives to develop newer and more efficacious medications. Developing truly innovative drugs requires a shift in the paradigms for drug discovery, which is already taking place by building on greatly expanded knowledge about the mechanisms involved in epileptogenesis, seizure generation, seizure spread and development of co-morbidities. AED development can also benefit by a review of the methodology currently applied in clinical AED development, in order to address a number of ethical and scientific concerns. As discussed in this article, many processes of clinical drug development, from proof-of-concept-studies to ambitious programs aimed at demonstrating antiepileptogenesis and disease-modification, can be facilitated by a greater integration of preclinical and clinical science, and by application of knowledge acquired during decades of controlled epilepsy trials. Copyright © 2015 Elsevier Ltd. All rights reserved.
Khushf, George
2010-06-01
Many accounts of the historical development of neurological criteria for determination of death insufficiently distinguish between two strands of interpretation advanced by advocates of a "whole-brain" criterion. One strand focuses on the brain as the organ of integration. Another provides a far more complex and nuanced account, both of death and of a policy on the determination of death. Current criticisms of the whole-brain criterion are effective in refuting the first interpretation, but not the second, which is advanced in the 2008 President's Council report on the determination of death. In this essay, I seek to further develop this second strand of interpretation. I argue that policy on determination of death aligns moral, biological, and ontological death concepts. Morally, death marks the stage when respect is no longer owed. Biologically, death concerns integrated functioning of an organism as a whole. But the biological concepts are underdetermined. The moral concerns lead to selection of strong individuality concepts rather than weak ones. They also push criteria to the "far side" of the dying process. There is a countervailing consideration associated with optimizing the number of available organs, and this pushes to the "near side" of death. Policy is governed by a conviction that it is possible to align these moral and biological death concepts, but this conviction simply lays out an agenda. There is also a prescription-integral to the dead donor rule-that lexically prioritizes the deontic concerns and that seeks to balance the countervailing tendencies by using science-based refinements to make the line between life and death more precise. After showing how these concerns have been effectively aligned in the current policy, I present a modified variant of a "division" scenario and show how an "inverse decapitation problem" leads to a conclusive refutation of the nonbrain account of death.
The evolution of the high-speed civil transport
NASA Technical Reports Server (NTRS)
Spearman, M. Leroy
1994-01-01
Current research directed toward the technology requirements for a high-speed civil transport (HSCT) airplane is an outgrowth of many years of activity related to air transportation. The purpose was to review some of the events that provided the background upon which current research programs are built. The review will include the subsonic era of transport aircraft and some events of the supersonic era that are related to the development of commercial supersonic transport aircraft. These events include the early NASA in-house studies and industry evaluations, the U.S. Supersonic Transport (SST) Program, the follow-on NASA supersonic cruise research programs, and the issuance of the National Aeronautical Research and Development (R&D) goals. Observations are made concerning some of the factors, both technical and nontechnical, that have had an impact on HSCT studies.
Studies on the current state of water quality in the Segamat River
NASA Astrophysics Data System (ADS)
Razelan, Faridah Mohd; Tahir, Wardah; E. M Yahaya, Nasehir Khan
2018-04-01
Nowadays, pollution has become a major concern in developed and developing countries. In a study on the current state of Segamat River water quality; on-site data collection and observation and also laboratory data analysis have been implemented. Studies showed that the downstream of the Segamat River has recorded a significant reduction in quality of water during the dry season compared to the wet season. The deterioration of water quality is caused by the activities along the river such as palm oil plantation, municipal waste and waste from settlements. It was also recorded that the point sources were dominating the pollution at Segamat River during the dry season. However, during the wet season, the water quality was impaired by the non-point sources which originated from the upstream of the river.
NASA Astrophysics Data System (ADS)
Dörner, Ralf; Lok, Benjamin; Broll, Wolfgang
Backed by a large consumer market, entertainment and education applications have spurred developments in the fields of real-time rendering and interactive computer graphics. Relying on Computer Graphics methodologies, Virtual Reality and Augmented Reality benefited indirectly from this; however, there is no large scale demand for VR and AR in gaming and learning. What are the shortcomings of current VR/AR technology that prevent a widespread use in these application areas? What advances in VR/AR will be necessary? And what might future “VR-enhanced” gaming and learning look like? Which role can and will Virtual Humans play? Concerning these questions, this article analyzes the current situation and provides an outlook on future developments. The focus is on social gaming and learning.
Electrostatically focused intensified charge coupled devices
NASA Technical Reports Server (NTRS)
Walker, J. W.
1977-01-01
Work performed to develop intensified charge coupled devices (ICCDs) is presented. Four ICCDs, containing 100 x 160 arrays, were fabricated. Electron gains up to 3200 at 15 keV were achieved. Photocathode sensitivities ranged from 190 to 410 micro A/lumen. Dark currents varied from 11 nA/sq cm to 37 nA/sq cm. There was serious concern about the reliability of the bonding scheme for ICCDs due to occassional bond failure. Two solutions to this problem were developed. One involved a modification of the existing bonding technique, and the other was the development of a protected bond pad employing a barrier metal between the aluminum metallization and the gold bond wire. An accumulation process was characterized with respect to its most critical variable. This characterization led to the achievement of reproducible spectral response and the discovery and elimination of dark current increase associated with this process.
Aquinas's account of human embryogenesis and recent interpretations.
Eberl, Jason T
2005-08-01
In addressing bioethical issues at the beginning of human life, such as abortion, in vitro fertilization, and embryonic stem cell research, one primary concern regards establishing when a developing human embryo or fetus can be considered a person. Thomas Aquinas argues that an embryo or fetus is not a human person until its body is informed by a rational soul. Aquinas's explicit account of human embryogenesis has been generally rejected by contemporary scholars due to its dependence upon medieval biological data, which has been far surpassed by current scientific research. A number of scholars, however, have attempted to combine Aquinas's basic metaphysical account of human nature with current embryological data to develop a contemporary Thomistic account of a human person's beginning. In this article, I discuss two recent interpretations in which it is argued that a human person does not begin to exist until a fetus has developed a functioning cerebral cortex.
Modeling local chemistry in PWR steam generator crevices
DOE Office of Scientific and Technical Information (OSTI.GOV)
Millett, P.J.
1997-02-01
Over the past two decades steam generator corrosion damage has been a major cost impact to PWR owners. Crevices and occluded regions create thermal-hydraulic conditions where aggressive impurities can become highly concentrated, promoting localized corrosion of the tubing and support structure materials. The type of corrosion varies depending on the local conditions, with stress corrosion cracking being the phenomenon of most current concern. A major goal of the EPRI research in this area has been to develop models of the concentration process and resulting crevice chemistry conditions. These models may then be used to predict crevice chemistry based on knowledgemore » of bulk chemistry, thereby allowing the operator to control corrosion damage. Rigorous deterministic models have not yet been developed; however, empirical approaches have shown promise and are reflected in current versions of the industry-developed secondary water chemistry guidelines.« less
The Technical Problems of Anti-theft Diagnostics in a Traction Network
NASA Astrophysics Data System (ADS)
Mikulski, Jerzy; Młynczak, Jakub
2012-02-01
The paper presents an analysis of traction lines theft in the Katowice division of the Railroad Development Company (Zakład Linii Kolejowych - ZLK) as well as the principles for the anti-theft protection system, currently in development. The problem of theft is a very important issue concerning the safety of rail transportation. It is also a significant economic problem, as the cost of recreating a stolen network is very high. Moreover, the Administrator of the infrastructure bears the cost of compensation for any delays in train schedules.
VMEbus based computer and real-time UNIX as infrastructure of DAQ
DOE Office of Scientific and Technical Information (OSTI.GOV)
Yasu, Y.; Fujii, H.; Nomachi, M.
1994-12-31
This paper describes what the authors have constructed as the infrastructure of data acquisition system (DAQ). The paper reports recent developments concerned with HP VME board computer with LynxOS (HP742rt/HP-RT) and Alpha/OSF1 with VMEbus adapter. The paper also reports current status of developing a Benchmark Suite for Data Acquisition (DAQBENCH) for measuring not only the performance of VME/CAMAC access but also that of the context switching, the inter-process communications and so on, for various computers including Workstation-based systems and VME board computers.
Roberts, Thomas G
2008-01-01
The development of "targeted biologics" as cancer therapy has made the field ripe for investment from the private sector and is changing the face of cancer medicine, while also raising important policy concerns about price, profit, and continued innovation. In this interview Barbara Culliton talks with Thomas Roberts, who sees this world from a unique perspective. Roberts, an oncologist, has practiced at the Massachusetts General Hospital and is currently thinking about innovation as a hedge fund manager.
Space station environmental control and life support systems conceptual studies
NASA Technical Reports Server (NTRS)
Humphries, W. R.; Powell, L. E.
1985-01-01
It is pointed out that the establishment of a permanent manned Space Station requires the development of a comprehensive approach which combines new technologies and existing spacecraft subsystem capabilities into an optimum design. The present paper is concerned with studies which were conducted in connection with the development of the regenerative Environmental Control and Life Support Systems (ECLSS) for the Space Station. Attention is given to the current state of the ECLSS subsystems and system level analytical selection and group studies related to the integrated system conceptual design.
NASA Technical Reports Server (NTRS)
Goochee, Charles F.
1987-01-01
The purpose is to review some of the physical/metabolic factors which must be considered in the development of an operating strategy for a mammalian cell bioreactor. Emphasis is placed on the dissolved oxygen and carbon dioxide requirements of growing mammalian epithelial cells. Literature reviews concerning oxygen and carbon dioxide requirements are discussed. A preliminary, dynamic model which encompasses the current features of the NASA bioreactor is presented. The implications of the literature survey and modeling effort on the design and operation of the NASA bioreactor are discussed.
Current Status Of Ergonomic Standards
NASA Astrophysics Data System (ADS)
Lynch, Gene
1984-05-01
The last five years have seen the development and adoption of new kinds of standards for the display industry. This standardization activity deals with the complex human computer interface. Here the concerns involve health, safety, productivity, and operator well-being. The standards attempt to specify the "proper" use of visual display units. There is a wide range of implications for the display industry - as manufacturers of displays, as employers, and as users of visual display units. In this paper we examine the development of these standards, their impact on the display industry and implications for the future.
Compressible Navier-Stokes equations: A study of leading edge effects
NASA Technical Reports Server (NTRS)
Hariharan, S. I.; Karbhari, P. R.
1987-01-01
A computational method is developed that allows numerical calculations of the time dependent compressible Navier-Stokes equations.The current results concern a study of flow past a semi-infinite flat plate.Flow develops from given inflow conditions upstream and passes over the flat plate to leave the computational domain without reflecting at the downstream boundary. Leading edge effects are included in this paper. In addition, specification of a heated region which gets convected with the flow is considered. The time history of this convection is obtained, and it exhibits a wave phenomena.
Global trends on fears and concerns of genetic discrimination: a systematic literature review.
Wauters, Annet; Van Hoyweghen, Ine
2016-04-01
Since the 1990s, developments in the field of genetics have led to many questions on the use and possible misuse of genetic information. 'Genetic discrimination' has been defined as the differential treatment of asymptomatic individuals or their relatives on the basis of their real or assumed genetic characteristics. Despite the public policy attention around genetic discrimination, there is currently still much confusion surrounding this phenomenon. On the one hand, there is little evidence of the occurrence of genetic discrimination. On the other hand, it appears that people remain concerned about this theme, and this fear influences their health and life choices. This article makes use of a systematic literature review to investigate what is already known about the nature, extent and background of these fears and concerns. The 42 included studies have found considerable levels of concerns about genetic discrimination. Concerns dominate in insurance contexts and within personal interactions. The extent of concerns appears to vary depending on the type of genetic illness. Furthermore, installed laws prohibiting genetic discrimination do not seem to alleviate existing fears. This raises important questions as to the origins of these fears. Based on the findings, recommendations for future research are made. First, research on the background of fears is needed. Second, future research needs to assess more fully all different forms (for example, direct and indirect) of genetic discrimination. Thirdly, it has to be studied whether genetic discrimination is a form of discrimination that is distinguishable from discrimination based on an illness or disability. Finally, a last element that should be addressed in future research is the most recent developments in research on genomics, such as next-generation sequencing or genome-wide association studies.
Preliminary Screening Procedures and Criteria for Replacements for Halons 1211 and 1301
1991-07-01
suppressants that meet current environmental and toxicological concerns. However, as the multiple and evolving performance constraints tighten, a new...massive trial-and-error study now may find suppressants that meet current environmental and toxicological concerns. However, as the multiple and...Extinguishment Concentration vs. Ratio of Linear Vapor Velocities, Elevated/hot ..................................................... 59 10. NIST PMMA Burner
Understanding Teachers' Professional Learning Goals from Their Current Professional Concerns
ERIC Educational Resources Information Center
Louws, Monika L.; Meirink, Jacobiene A.; van Veen, Klaas; van Driel, Jan H.
2018-01-01
In the day-to-day workplace teachers direct their own learning, but little is known about what drives their decisions about what they would like to learn. These decisions are assumed to be influenced by teachers' current professional concerns. Also, teachers in different professional life phases have different reasons for engaging in professional…
ERIC Educational Resources Information Center
Cooper, Leigh A.; Nickerson, Amanda B.
2013-01-01
In this study, parent history of bullying was examined in terms of general involvement with bullying, specific types of bullying experienced, level of hurtfulness associated with the experience, and when bullying occurred. Parent current views, levels of concern, and strategies used to cope with bullying were also evaluated. Finally, the…
Speaking out on Matters of Public Concern: The Precarious Nature of School Administrator Speech
ERIC Educational Resources Information Center
Geisel, Richard T.
2015-01-01
The purpose of this paper is to highlight current U.S. Supreme Court precedents regarding public employee speech on matters of public concern, and how those precedents are being applied by lower federal courts to public school administrators. Surveying the current legal landscape reveals a heightened vulnerability for school administrators…
Interplanetary magnetic field effects on high latitude ionospheric convection
NASA Technical Reports Server (NTRS)
Heelis, R. A.
1985-01-01
Relations between the electric field and the electric current in the ionosphere can be established on the basis of a system of mathematical and physical equations provided by the equations of current continuity and Ohm's law. For this reason, much of the synthesis of electric field and plasma velocity data in the F-region is made with the aid of similar data sets derived from field-aligned current and horizontal current measurements. During the past decade, the development of a self-consistent picture of the distribution and behavior of these measurements has proceeded almost in parallel. The present paper is concerned with the picture as it applies to the electric field and plasma drift velocity and its dependence on the interplanetary magnetic field. Attention is given to the southward interplanetary magnetic field and the northward interplanetary magnetic field.
Bakhiyi, Bouchra; Labrèche, France; Zayed, Joseph
2014-12-01
As it supplies solar power, a priori considered harmless for the environment and human health compared with fossil fuels, the photovoltaic (PV) industry seems to contribute optimally to reduce greenhouse gas emissions and, overall, to sustainable development. However, considering the forecast for rapid growth, its use of potentially toxic substances and manufacturing processes presenting health and safety problems may jeopardize its benefits. This paper aims to establish a profile of the PV industry in order to determine current and emerging environmental and health concerns. A review of PV system life cycle assessments, in light of the current state of the industry and its developmental prospects, reveals information deficits concerning some sensitive life cycle indicators and environmental impacts, together with incomplete information on toxicological data and studies of workers' exposure to different chemical and physical hazards. Although solar panel installation is generally considered relatively safe, the occupational health concerns related to the growing number of hazardous materials handled in the PV industry warrants an all-inclusive occupational health and safety approach in order to achieve an optimal equilibrium with sustainability. To prevent eco-health problems from offsetting the benefits currently offered by the PV industry, manufacturers should cooperate actively with workers, researchers and government agencies toward improved and more transparent research, the adoption of specific and stricter regulations, the implementation of preventive risk management of occupational health and safety and, lastly, greater responsibilization toward PV systems from their design until their end of life. Copyright © 2014 Elsevier Ltd. All rights reserved.
ERIC Educational Resources Information Center
Horne, Arthur M.
2013-01-01
The predoctoral relationship that counseling psychology programs have had with master's programs over the decades is being challenged in current times. A model that is developing is one that provides greater responsibility for program definition and then full faculty engagement from doctoral program faculty. With change occurring in training…
A report of a Conference on Advanced Composites: An Assessment of the Future
NASA Technical Reports Server (NTRS)
Harris, L. A.
1977-01-01
A conference was held to evaluate the current status and future commitment to composites by government and industry. This reassessment, was felt needed because of an apparent transition in the acceptance of composites. The management of government agencies restated their progress and commitment to the development of composites and industrial management defined their concerns and requirements to commit to the future use of composites.
ERIC Educational Resources Information Center
Hand, Brian; Cavagnetto, Andy; Chen, Ying-Chih; Park, Soonhye
2016-01-01
Given current concerns internationally about student performance in science and the need to shift how science is being learnt in schools, as a community, we need to shift how we approach the issue of learning and teaching in science. In the future, we are going to have to close the gap between how students construct and engage with knowledge in a…
Fairer global trade, better local health.
Mussi, Aldo
2008-01-01
Trade is an inevitable part of human interaction, and our current economy is concerned more with quantity than with quality of trade. Trade justice is an essential part of sustainable development, and the Fairtrade movement allows us in the rich world to make clear commitment to this. The health benefits are not just in the poor world but benefit the rich too because of the importance of the social environment to our health.
Broschard, Thomas H; Glowienke, Susanne; Bruen, Uma S; Nagao, Lee M; Teasdale, Andrew; Stults, Cheryl L M; Li, Kim L; Iciek, Laurie A; Erexson, Greg; Martin, Elizabeth A; Ball, Douglas J
2016-11-01
Leachables from pharmaceutical container closure systems can present potential safety risks to patients. Extractables studies may be performed as a risk mitigation activity to identify potential leachables for dosage forms with a high degree of concern associated with the route of administration. To address safety concerns, approaches to toxicological safety evaluation of extractables and leachables have been developed and applied by pharmaceutical and biologics manufacturers. Details of these approaches may differ depending on the nature of the final drug product. These may include application, the formulation, route of administration and length of use. Current regulatory guidelines and industry standards provide general guidance on compound specific safety assessments but do not provide a comprehensive approach to safety evaluations of leachables and/or extractables. This paper provides a perspective on approaches to safety evaluations by reviewing and applying general concepts and integrating key steps in the toxicological evaluation of individual extractables or leachables. These include application of structure activity relationship studies, development of permitted daily exposure (PDE) values, and use of safety threshold concepts. Case studies are provided. The concepts presented seek to encourage discussion in the scientific community, and are not intended to represent a final opinion or "guidelines." Copyright © 2016 Elsevier Inc. All rights reserved.
NCI Think Tank Concerning the Identifiability of Biospecimens and “-Omic” Data
Weil, Carol J.; Mechanic, Leah E.; Green, Tiffany; Kinsinger, Christopher; Lockhart, Nicole C.; Nelson, Stefanie A.; Rodriguez, Laura L.; Buccini, Laura D.
2014-01-01
On June 11 and 12, 2012, the National Cancer Institute (NCI) hosted a think tank concerning the identifiability of biospecimens and “omic” Data in order to explore challenges surrounding this complex and multifaceted topic. The think tank brought together forty-six leaders from several fields, including cancer genomics, bioinformatics, human subject protection, patient advocacy, and commercial genetics. The first day involved presentations regarding the state of the science of re-identification; current and proposed regulatory frameworks for assessing identifiability; developments in law, industry and biotechnology; and the expectations of patients and research participants. The second day was spent by think tank participants in small break-out groups designed to address specific sub-topics under the umbrella issue of identifiability, including considerations for the development of best practices for data sharing and consent, and targeted opportunities for further empirical research. We describe the outcomes of this two day meeting, including two complimentary themes that emerged from moderated discussions following the presentations on Day 1, and ideas presented for further empirical research to discern the preferences and concerns of research participants about data sharing and individual identifiability. PMID:23579437
Van Nieuwenhove, I; Tytgat, L; Ryx, M; Blondeel, P; Stillaert, F; Thienpont, H; Ottevaere, H; Dubruel, P; Van Vlierberghe, S
2017-11-01
There is a clear and urgent clinical need to develop soft tissue fillers that outperform the materials currently used for adipose tissue reconstruction. Recently, extensive research has been performed within this field of adipose tissue engineering as the commercially available products and the currently existing techniques are concomitant with several disadvantages. Commercial products are highly expensive and associated with an imposing need for repeated injections. Lipofilling or free fat transfer has an unpredictable outcome with respect to cell survival and potential resorption of the fat grafts. Therefore, researchers are predominantly investigating two challenging adipose tissue engineering strategies: in situ injectable materials and porous 3D printed scaffolds. The present work provides an overview of current research encompassing synthetic, biopolymer-based and extracellular matrix-derived materials with a clear focus on emerging fabrication technologies and developments realized throughout the last decade. Moreover, clinical relevance of the most promising materials will be discussed, together with potential concerns associated with their application in the clinic. Copyright © 2017 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved.
DOT National Transportation Integrated Search
2017-06-01
Road safety concerns are a legitimate concern when promoting increased bicycle use. Currently, bicyclist traffic fatalities and injuries present both a public health concern and a disincentive to people taking up or continuing to bicycle for transpor...
Welfare of apes in captive environments: comments on, and by, a specific group of apes.
Savage-Rumbaugh, Sue; Wamba, Kanzi; Wamba, Panbanisha; Wamba, Nyota
2007-01-01
Accurately determining the proper captive environment for apes requires adequately assessing the psychological similarities between apes and humans. Scientists currently believe apes lack mental complexity (Millikan, 2006), raising questions concerning the evolution of human culture from ape-like societies (Tomasello, 1999). A long-term cultural study with bonobos suggests less intellectual divergence from humans than currently postulated (Savage-Rumbaugh, 2005). Because humans view apes as mentally limited, some current captive environments may appear idyllic while offering only an illusion of appropriate care, derived from a simplistic view of what apes are, rather than what they might be. This perception of apes determines their handling, which determines their mental development, which perpetuates the prevailing perception. Only breaking this cycle will allow the current perception of apes to change. Their usual captive environment limits any demonstration of culture. However, the bonobo study reveals what ape culture can become, which should affect future welfare considerations for at least those species genetically close to humans (bonobos and chimpanzees). Development of a languaged bonobo culture allows these nonhuman animals to provide their own responses regarding adequate ape welfare.
Comparing Teaching Approaches About Maxwell's Displacement Current
NASA Astrophysics Data System (ADS)
Karam, Ricardo; Coimbra, Debora; Pietrocola, Maurício
2014-08-01
Due to its fundamental role for the consolidation of Maxwell's equations, the displacement current is one of the most important topics of any introductory course on electromagnetism. Moreover, this episode is widely used by historians and philosophers of science as a case study to investigate several issues (e.g. the theory-experiment relationship). Despite the consensus among physics educators concerning the relevance of the topic, there are many possible ways to interpret and justify the need for the displacement current term. With the goal of understanding the didactical transposition of this topic more deeply, we investigate three of its domains: (1) The historical development of Maxwell's reasoning; (2) Different approaches to justify the term insertion in physics textbooks; and (3) Four lectures devoted to introduce the topic in undergraduate level given by four different professors. By reflecting on the differences between these three domains, significant evidence for the knowledge transformation caused by the didactization of this episode is provided. The main purpose of this comparative analysis is to assist physics educators in developing an epistemological surveillance regarding the teaching and learning of the displacement current.
Stormy weather: race, gene expression, and the science of health disparities.
Krieger, Nancy
2005-12-01
In the current US political climate, conservative foundations are seeking to frame debates over determinants of racial/ethnic health disparities as a matter of "politically correct" unscientific ideology (concerning the health impacts of discrimination) vs scientific yet "politically incorrect" expertise rooted in biological facts (concerning genes). I draw on historical and contemporary examples to place conservative polemics in context, and also highlight fundamental flaws in their arguments involving the use of spurious categories (e.g., Caucasian), logical fallacies, temporal fallacies, and an erroneous emphasis on gene frequency over gene expression. The larger goal is to strengthen development of a more critical, reflexive, and rigorous science capable of generating evidence useful for rectifying--rather than perpetuating--social disparities in health.
Developing a pharmaceutical purchasing strategy.
Hynniman, C E
1992-09-01
The process commonly used by group purchasing organizations to contract for multisource pharmaceuticals and a strategic approach for the director of pharmacy in working with the purchasing group and the P & T Committee is described. The pharmacist should be knowledgeable concerning the group's contract commitment requirements, product specifications, terms and conditions and procedures for vendor selection, product award, contract implementation, and performance monitoring. To ensure results that meet the needs of the medical staff, it is important that the P & T Committee actively participate. The P & T Committee should understand the reasons for selecting a particular purchasing group, understand the necessary steps in obtaining the most favorable economic advantage, review products with potential brand interchange concerns, recommend product specifications, and reaffirm formulary procedures regarding the principle of current consent.
Membrane lipids and the origin of life
NASA Technical Reports Server (NTRS)
Oro, J.; Holzer, G.; Rao, M.; Tornabene, T. G.
1981-01-01
The current state of knowledge regarding the development of biological systems is briefly reviewed. At a crucial stage concerning the evolution of such systems, the mechanisms leading to more complex structures must have evolved within the confines of a protected microenvironment, similar to those provided by the contemporary cell membranes. The major components found normally in biomembranes are phospholipids. The structure of the biomembrane is examined, and attention is given to questions concerning the availability of the structural components which are necessary in the formation of primitive lipid membranes. Two approaches regarding the study of protomembranes are discussed. The probability of obtaining ether lipids under prebiotic conditions is considered, taking into account the formation of cyclic and acyclic isoprenoids by the irradiation of isoprene with UV.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Litchfield, J.W.; Watts, R.L.; Gurwell, W.E.
A materials assessment methodology for identifying specific critical material requirements that could hinder the implementation of solar energy has been developed and demonstrated. The methodology involves an initial screening process, followed by a more detailed materials assessment. The detailed assessment considers such materials concerns and constraints as: process and production constraints, reserve and resource limitations, lack of alternative supply sources, geopolitical problems, environmental and energy concerns, time constraints, and economic constraints. Data for 55 bulk and 53 raw materials are currently available on the data base. These materials are required in the example photovoltaic systems. One photovoltaic system and thirteenmore » photovoltaic cells, ten solar heating and cooling systems, and two agricultural and industrial process heat systems have been characterized to define their engineering and bulk material requirements.« less
Stormy Weather: Race, Gene Expression, and the Science of Health Disparities
Krieger, Nancy
2005-01-01
In the current US political climate, conservative foundations are seeking to frame debates over determinants of racial/ethnic health disparities as a matter of “politically correct” unscientific ideology (concerning the health impacts of discrimination) vs scientific yet “politically incorrect” expertise rooted in biological facts (concerning genes). I draw on historical and contemporary examples to place conservative polemics in context, and also highlight fundamental flaws in their arguments involving the use of spurious categories (e.g., Caucasian), logical fallacies, temporal fallacies, and an erroneous emphasis on gene frequency over gene expression. The larger goal is to strengthen development of a more critical, reflexive, and rigorous science capable of generating evidence useful for rectifying—rather than perpetuating—social disparities in health. PMID:16257941
Principles of a multistack electrochemical wastewater treatment design
NASA Astrophysics Data System (ADS)
Elsahwi, Essam S.; Dawson, Francis P.; Ruda, Harry E.
2018-02-01
Electrolyzer stacks in a bipolar architecture (cells connected in series) are desirable since power provided to a stack can be transferred at high voltages and low currents and thus the losses in the power bus can be reduced. The anode electrodes (active electrodes) considered as part of this study are single sided but there are manufacturing cost advantages to implementing double side anodes in the future. One of the main concerns with a bipolar stack implementation is the existence of leakage currents (bypass currents). The leakage current is associated with current paths that are not between adjacent anode and cathode pairs. This leads to non uniform current density distributions which compromise the electrochemical conversion efficiency of the stack and can also lead to unwanted side reactions. The objective of this paper is to develop modelling tools for a bipolar architecture consisting of two single sided cells that use single sided anodes. It is assumed that chemical reactions are single electron transfer rate limited and that diffusion and convection effects can be ignored. The design process consists of the flowing two steps: development of a large signal model for the stack, and then the extraction of a small signal model from the large signal model. The small signal model facilitates the design of a controller that satisfies current or voltage regulation requirements. A model has been developed for a single cell and two cells in series but can be generalized to more than two cells in series and to incorporate double sided anode configurations in the future. The developed model is able to determine the leakage current and thus provide a quantitative assessment on the performance of the cell.
NASA Astrophysics Data System (ADS)
Masaitis, Alexandra
2014-05-01
New economic, environmental and social challenges for the mining industry in the USA show the need to implement "responsible" mining practices that include improved community involvement. Conflicts which occur in the US territory and with US mining companies around the world are now common between the mining proponents, NGO's and communities. These conflicts can sometimes be alleviated by early development of modes of communication, and a formal discussion format that allows airing of concerns and potential resolution of problems. One of the methods that can formalize this process is to establish a Good Neighbor Agreement (GNA), which deals specifically with challenges in relationships between mining operations and the local communities. It is a new practice related to mining operations that are oriented toward social needs and concerns of local communities that arise during the normal life of a mine, which can achieve sustainable mining practices. The GNA project being currently developed at the University of Nevada, USA in cooperation with the Newmont Mining Corporation has a goal of creating an open company/community dialog that will help identify and address sociological and environmental concerns associated with mining. Discussion: The Good Neighbor Agreement currently evolving will address the following: 1. Identify spheres of possible cooperation between mining companies, government organizations, and NGO's. 2. Provide an economically viable mechanism for developing a partnership between mining operations and the local communities that will increase mining industry's accountability and provide higher levels of confidence for the community that a mine is operated in a safe and sustainable manner. Implementation of the GNA can help identify and evaluate conflict criteria in mining/community relationships; determine the status of concerns; determine the role and responsibilities of stakeholders; analyze problem resolution feasibility; maintain the community involvement and support through economic benefits and environmental safeguards; develop options for the concerns resolution. Difficulties in establishing the GNA standards include lack of insurance/bonding policies, and by the lack of audit and monitoring that could determine the level of exposure of the local community and the environment to the contaminants released at the mine sites. Since many problems of mines can occur during closure and post-closure, GNA's should address those issues also. The goal of the GNA is to have open access for the public to the safety, health, and environmental information pertaining to the mining operation, as well as to educate the local communities about mining practices that promote mutual acknowledgment of the need to build a relationship amenable to each other's needs. Frequent conflicts between mining companies and surrounding communities lead to work disruptions or even mine closures and show the necessity of a less confrontational approach to environmental and social justice. The Good Neighbor Agreement is a unique way to provide the benefits for the both mining operations and local community to provide a mechanism for risk redaction and communication that offer the potential to protect both mining and community interests.
Phocas, F; Belloc, C; Bidanel, J; Delaby, L; Dourmad, J Y; Dumont, B; Ezanno, P; Fortun-Lamothe, L; Foucras, G; Frappat, B; González-García, E; Hazard, D; Larzul, C; Lubac, S; Mignon-Grasteau, S; Moreno, C R; Tixier-Boichard, M; Brochard, M
2016-11-01
Agroecology uses ecological processes and local resources rather than chemical inputs to develop productive and resilient livestock and crop production systems. In this context, breeding innovations are necessary to obtain animals that are both productive and adapted to a broad range of local contexts and diversity of systems. Breeding strategies to promote agroecological systems are similar for different animal species. However, current practices differ regarding the breeding of ruminants, pigs and poultry. Ruminant breeding is still an open system where farmers continue to choose their own breeds and strategies. Conversely, pig and poultry breeding is more or less the exclusive domain of international breeding companies which supply farmers with hybrid animals. Innovations in breeding strategies must therefore be adapted to the different species. In developed countries, reorienting current breeding programmes seems to be more effective than developing programmes dedicated to agroecological systems that will struggle to be really effective because of the small size of the populations currently concerned by such systems. Particular attention needs to be paid to determining the respective usefulness of cross-breeding v. straight breeding strategies of well-adapted local breeds. While cross-breeding may offer some immediate benefits in terms of improving certain traits that enable the animals to adapt well to local environmental conditions, it may be difficult to sustain these benefits in the longer term and could also induce an important loss of genetic diversity if the initial pure-bred populations are no longer produced. As well as supporting the value of within-breed diversity, we must preserve between-breed diversity in order to maintain numerous options for adaptation to a variety of production environments and contexts. This may involve specific public policies to maintain and characterize local breeds (in terms of both phenotypes and genotypes), which could be used more effectively if they benefited from the scientific and technical resources currently available for more common breeds. Last but not least, public policies need to enable improved information concerning the genetic resources and breeding tools available for the agroecological management of livestock production systems, and facilitate its assimilation by farmers and farm technicians.
Or, Calvin K.L.; Valdez, Rupa S.; Casper, Gail R.; Carayon, Pascale; Burke, Laura J.; Brennan, Patricia Flatley; Karsh, Ben-Tzion
2010-01-01
Sicker patients with greater care needs are being discharged to their homes to assume responsibility for their own care with fewer nurses available to aid them. This situation brings with it a host of human factors and ergonomic (HFE) concerns, both for the home care nurse and the home dwelling patient, that can affect quality of care and patient safety. Many of these concerns are related to the critical home care tasks of information access, communication, and patient self-monitoring and self-management. Currently, a variety of health information technologies (HITs) are being promoted as possible solutions to those problems, but those same technologies bring with them a new set of HFE concerns. This paper reviews the HFE considerations for information access, communication, and patients self-monitoring and self-management, discusses how HIT can potentially mitigate current problems, and explains how the design and implementation of HIT itself requires careful HFE attention. PMID:19713630
NASA Technical Reports Server (NTRS)
Laperriere, A. J.
1975-01-01
Past, present, and proposed applications of LANDSAT data for renewable resource assessments in Alaska are described. Specific projects briefly discussed include: a feasibility investigation applying LANDSAT data to caribou habitat mapping in northeast Alaska, analysis of a native corporate region in southwest Alaska, analysis of a game management unit in interior Alaska, and two proposed analyses in northwest Alaska. These analyses principally address range evaluations concerning caribou, moose, and Dall sheep, but results have application to other renewable resource themes. Application of resource assessment results to a statewide land use management plan is discussed.
The antibacterial peptide ABP-CM4: the current state of its production and applications.
Li, Jian Feng; Zhang, Jie; Xu, Xing Zhou; Han, Yang Yang; Cui, Xian Wei; Chen, Yu Qing; Zhang, Shuang Quan
2012-06-01
The increasing resistance of bacteria and fungi to currently available antibiotics is a major concern worldwide, leading to enormous efforts to develop new antibiotics with new modes of actions. Antibacterial peptide CM4 (ABP-CM4) is a small cationic peptide with broad-spectrum activities against bacteria, fungi, and tumor cells, which may possibly be used as a promising candidate for a new antibiotic. For pharmaceutical applications, a large quantity of antimicrobial peptides needs to be produced economically. In this communication, the progress in the structural characteristics, heterologous production, and biological evaluation of ABP-CM4 are reviewed.
NASA Astrophysics Data System (ADS)
Dodson, Maria
The underrepresentation of women enrolled in the physical sciences continues to challenge academic leaders despite over 40 years of programming to promote gender equity within these curricula. This study employed a quantitative, causal comparative method to explore if and to what extent career concerns differed among female and male undergraduate physical and biological science students. The theory of planned behavior and life-span, life-space theory served as the theoretical framework for the study. Quantitative survey data were collected from 43 students at four institutions across the United States. The findings indicated that undergraduate women in physical science programs of study had a significantly different level of concern about the Innovating sub-category of the third stage of career development, Maintenance, as compared to undergraduate women in biological science curricula [F(1,33) = 6.244, p = 0.018]. Additionally, there was a statistically significant difference between female undergraduate physical science students and undergraduate male science students in the sub-categories of Implementation [F(1,19) = 7.228, p = 0.015], Advancing [F(1,19) = 11.877, p = 0.003], and Innovating [F(1,19) = 11.782, p = 0.003] within the first three stages of career development (Exploration, Establishment, and Maintenance). The comparative differences among the study groups offers new information about undergraduate career concerns that may contribute to the underrepresentation of women enrolled in the physical sciences. Suggestions for future research and programs within higher education targeted at reducing the career concerns of current and prospective female students in physical science curricula are discussed.
Climate change and food security in East Asia.
Su, Yi-Yuan; Weng, Yi-Hao; Chiu, Ya-Wen
2009-01-01
Climate change causes serious food security risk for East Asian countries. The United Nations Framework Convention on Climate Change (UNFCCC) has recognized that the climate change will impact agriculture and all nations should prepare adaptations to the impacts on food security. This article reviews the context of adaptation rules and current policy development in East Asian region. The UNFCCC and Kyoto Protocol have established specific rules for countries to develop national or regional adaptation policies and measurements. The current development of the ASEAN Strategic Plan on food security is inspiring, but the commitments to implementation by its members remain an issue of concern. We suggest that the UNFCCC enhances co-operation with the Food and Agriculture Organization (FAO) and other international organizations to further develop methodologies and technologies for all parties. Our findings suggest that agriculture is one of the most vulnerable sectors in terms of risks associated with climate change and distinct programmatic initiatives are necessary. It's imperative to promote co-operation among multilateral organizations, including the UNFCCC, FAO, World Health Organization, and others.
Mdege, Noreen Dadirai; Chevo, Tafadzwa; Toner, Paul
There is increasing recognition of the potential significant contribution that pharmacy personnel can make to improve the public's health. However, there is an evidence gap in developing countries on the public health role of pharmacy personnel. This study aimed to explore the current public health activities that pharmacy professionals in Zimbabwe are currently involved in, and the potential of expanding this role. The study utilized individual, face-to-face, semi-structured qualitative interviews with 9 key informants. The sample reflected the diversity of pharmacy practice groups and levels as well as professional experience, and included a representative from a patient group, and a non-pharmacist national level public health expert. Data collection and analysis was an iterative process informed both by the currently available literature on the topic, as well as themes emerging from the data. Framework analysis was utilized with two independent analyses performed. There was a general consensus among participants that pharmacy practice in Zimbabwe was mainly focused on curative services, with very limited involvement in public health oriented activities. The following were identified as pharmacists' current public health activities: supply chain management of pharmaceutical products, provision of medications and other pharmaceutical products to patients, therapy monitoring, identification and monitoring of chronic illnesses, information provision and training of pharmacists. Nevertheless, there were concerns regarding the quality of some of these services, and lack of consistency in provision across pharmacies. Other potential areas for pharmacists' public health practice were identified as emergency response, drug abuse, addressing social determinants of health particularly promoting healthy lifestyles, applied health research, counterfeit and substandard medicines, and advocacy. There is perceived potential for Zimbabwean pharmacists to become more involved in public health oriented services. However, concerns regarding the quality of services and lack of consistency in provision need to be addressed. Copyright © 2015 Elsevier Inc. All rights reserved.
Aquatic Organic Matter Fluorescence - from phenomenon to application
NASA Astrophysics Data System (ADS)
Reynolds, Darren
2014-05-01
The use of fluorescence to quantify and characterise aquatic organic matter in river, ocean, ground water and drinking and waste waters has come along way since its discovery as a phenomenon in the early 20th century. For example, there are over 100 papers published each year in international peer reviewed journals, an order of magnitude increase since a decade ago (see Figure taken from ISI database from 1989 to 2007 for publications in the fields of river water and waste water). Since then it has been extensively used as a research tool since the 1990's by scientists and is currently used for a wide variety of applications within a number of sectors. Universities, organisations and companies that research into aquatic organic matter have either recently readily use appropriate fluorescence based techniques and instrumentation. In industry and government, the technology is being taken up by environmental regulators and water and wastewater companies. This keynote presentation will give an overview of aquatic organic matter fluorescence from its conception as a phenomenon through to its current use in a variety of emerging applications within the sectors concerned with understanding, managing and monitoring the aquatic environment. About the Speaker Darren Reynolds pioneered the use of fluorescence spectroscopy for the analysis of wastewaters in the 1990's. He currently leads a research group within the Centre for Research in Biosciences and sits on the Scientific Advisory Board for the Institute of Bio-Sensing Technology at the University of the West of England, Bristol. He is a multidisciplinary scientist concerned with the development of technology platforms for applications in the fields of environment/agri-food and health. His current research interests include the development of optical technologies and techniques for environmental and biological sensing and bio-prospecting applications. He is currently involved in the development and use of synthetic biology (bioluminescent reporter bacteria) for the discovery and characterization of bacteriophage and to assess their potential use as a bio-control/antimicrobial in the health and agri-food sectors. Presently, he is developing, in collaboration with industrial partners, in-situ fluorescence sensors to help further understand the role of dissolved organic matter in underpinning the microbial processes in aquatic systems through time, a project funded by the Natural Environment Research Council, UK.
Technical and operational users' opinions of a handheld device to detect directed energy.
Boyd, Andrew D; Naiman, Melissa; Stevenson, Greer W; Preston, Richard; Valenta, Annette L
2013-05-01
Lasers, a form of directed energy (DE), are a threat to pilots and Air Force personnel. In light of this threat, a handheld medical device called the "Tricorder" is under development to improve situational awareness of DE. Current operational procedures do not include methods for recording or handling new information regarding DE. The purpose of this study was to understand Air Force personnel opinions and beliefs about desired features and operational use to enhance user acceptance of the Tricorder. Q-methodology was implemented to study opinions and beliefs related to DE. Two groups were approached, medical personnel in the Illinois Air National Guard and four active duty members of an Air Force Rescue Squadron. Both groups completed the same Q-sort of both operational and equipment concerns. Six opinion sets regarding operational concerns described 61% of the total variation in perceptions among participants. The factors were: concern over health effects, implications to individuals, combat/tactical concerns, force health protection, and theater/tactical concerns. Five opinion sets described 68% of the variation in the equipment functions perceived as most important. The participants indicated that ideally the device should measure exposure, enhance laser detection/response, support night vision and ease of use, detect threats, and enhance combat medicine. This survey revealed the complexity of equipment and the operational implications of detecting DE. Q-methodology is a unique strategy to both evaluate technology and explore users' concerns.
Defending Against Smallpox: a Focus on Vaccines
Voigt, Emily A.; Kennedy, Richard B.; Poland, Gregory A.
2016-01-01
Smallpox has shaped human history, from the earliest human civilizations well into the 20th century. With high mortality rates, rapid transmission, and serious long-term effects on survivors, smallpox was a much-feared disease. The eradication of smallpox represents an unprecedented medical victory for the lasting benefit of human health and prosperity. Concerns remain, however, about the development and use of the smallpox virus as a biological weapon, which necessitates the need for continued vaccine development. Smallpox vaccine development is thus a much-reviewed topic of high interest. This review focuses on the current state of smallpox vaccines and their context in biodefense efforts. PMID:27049653
Defending against smallpox: a focus on vaccines.
Voigt, Emily A; Kennedy, Richard B; Poland, Gregory A
2016-09-01
Smallpox has shaped human history, from the earliest human civilizations well into the 20th century. With high mortality rates, rapid transmission, and serious long-term effects on survivors, smallpox was a much-feared disease. The eradication of smallpox represents an unprecedented medical victory for the lasting benefit of human health and prosperity. Concerns remain, however, about the development and use of the smallpox virus as a biological weapon, which necessitates the need for continued vaccine development. Smallpox vaccine development is thus a much-reviewed topic of high interest. This review focuses on the current state of smallpox vaccines and their context in biodefense efforts.
Henson, Spencer; Humphrey, John
2010-01-01
The increasing prevalence of private standards governing food safety, food quality and environmental and social impacts of agri-food systems has raised concerns about the effects on developing countries, as well as the governance of agri-food value chains more broadly. It is argued that current debates have been 'clouded' by a failure to recognise the diversity of private standards in terms of their institutional form, who develops and adopts these standards and why. In particular, there is a need to appreciate the close inter-relationships between public regulations and private standards and the continuing ways in which private standards evolve.
Ferrario, Daniele; Rabbit, Richard R
2012-01-01
On June 12, 2009, the European Commission adopted a proposal for a Regulation concerning the placement on the market and use of biocidal products, which, when it enters into force on January 1, 2013, will repeal and replace Directive 98/8/EC. The main reason for the revision of the current Directive was to promote best practices for environmental and human health protection, along with implementation of current developments in safety testing in order to create safer biocides. Moreover, the proposed Regulation aims to take into consideration the newest legislation on chemicals. This article evaluates the proposed Regulation in comparison to Directive 98/8/EC. Although the new proposal requires the sharing of vertebrate animal test data, both for product authorization and for newly developed active substances, it misses - in contrast to REACH - the opportunity to recognize the accelerating development of alternative approaches to animal testing, most recently with new momentum provided by "Toxicity Testing for the 21st Century", and to support the evolution of toxicology towards a new approach to testing. The new methods promise not only to decrease animal pain and suffering, but also to provide faster results and better prediction for human risk assessment compared to traditional methods. Unfortunately, methods mandated for human risk assessment in the proposal are still mainly based on traditional animal study extrapolation. We put forward and discuss possible alternative strategies, such as in vitro testing, integrated testing strategies, toxicokinetics, "omics", systems biology, bioinformatics, and computational modeling, all of which could be more encouraged by the proposal. Current opportunities to improve our tools for biocide risk assessment are discussed, delineating advantages, limitations, and development needs. It is suggested to open the proposed Regulation to alternative approaches that are based on human biology more than on extrapolation from animals to humans.
Pest management under climate change: The importance of understanding tritrophic relations.
Castex, V; Beniston, M; Calanca, P; Fleury, D; Moreau, J
2018-03-01
Plants and insects depend on climatic factors (temperature, solar radiation, precipitations, relative humidity and CO 2 ) for their development. Current knowledge suggests that climate change can alter plants and insects development and affect their interactions. Shifts in tritrophic relations are of particular concern for Integrated Pest Management (IPM), because responses at the highest trophic level (natural enemies) are highly sensitive to warmer temperature. It is expected that natural enemies could benefit from better conditions for their development in northern latitudes and IPM could be facilitated by a longer period of overlap. This may not be the case in southern latitudes, where climate could become too warm. Adapting IPM to future climatic conditions requires therefore understanding of changes that occur at the various levels and their linkages. The aim of this review is to assess the current state of knowledge and highlights the gaps in the existing literature concerning how climate change can affect tritrophic relations. Because of the economic importance of wine production, the interactions between grapevine, Vitis vinifera (1st), Lobesia botrana (2nd) and Trichogramma spp., (3rd), an egg parasitoid of Lobesia botrana, are considered as a case study for addressing specific issues. In addition, we discuss models that could be applied in order quantify alterations in the synchrony or asynchrony patterns but also the shifts in the timing and spatial distribution of hosts, pests and their natural enemies. Copyright © 2017 Elsevier B.V. All rights reserved.
Kufel, Wesley D; Zayac, Adam S; Lehmann, David F; Miller, Christopher D
2016-11-01
Despite prescribing guidance, limited data exist to describe the use of apixaban in patients with end-stage renal disease (ESRD) requiring hemodialysis (HD). Current apixaban dosing recommendations for this patient population are based largely on a single-dose pharmacokinetic study of eight patients. We describe the clinical application and pharmacodynamic monitoring of apixaban in a 62-year-old 156-kg African-American woman with nonvalvular atrial fibrillation and ESRD requiring hemodialysis who developed calciphylaxis while receiving warfarin therapy. Based on a multidisciplinary clinical judgment decision due to concern for drug accumulation after multiple doses in patients with ESRD receiving HD, she was anticoagulated with apixaban 2.5 mg twice/day, as opposed to 5 mg twice/day as recommended by the package insert. Antifactor Xa monitoring was used, and resultant peak and trough apixaban concentrations were above the upper limit of detection for our clinical laboratory (more than 2.00 IU/ml). On day 7 of her hospitalization, the patient developed gastrointestinal bleeding, and apixaban was discontinued; no further clinical signs of bleeding occurred during her subsequent hospitalization course. Use of the Naranjo Adverse Drug Reaction Probability Scale indicated a probable relationship (score of 6) between apixaban exposure and the manifestation of gastrointestinal bleeding. The patient ultimately died 44 days after the acute bleeding event; however, coagulation concerns were not implicated in the patient's death. To our knowledge, this is the first case report that describes apixaban use and associated antifactor Xa monitoring in a patient with ESRD receiving HD, and it provides concern for current apixaban dosing recommendations in this patient population. Further pharmacokinetic and clinical data are likely necessary to better characterize apixaban use in these patients to optimize safety and efficacy. © 2016 Pharmacotherapy Publications, Inc.
OVERVIEW OF EMERGING CONTAMINANTS OF CONCERN IN DRINKING WATER
Much has been achieved in the way of environmental protection over the last 30 years. However, as we learn more, new concerns arise. This presentation will discuss chemical and microbial contaminants that the U.S. EPA and other agencies are currently concerned about. In this grou...
NASA Astrophysics Data System (ADS)
Jia, Shenli; Mo, Yongpeng; Shi, Zongqian; Li, Junliang; Wang, Lijun
2017-10-01
The post-arc dielectric recovery process has a decisive effect on the current interruption performance in a vacuum circuit breaker. The dissipation of residual plasma at the moment of current zero under the transient recovery voltage, which is the first stage of the post-arc dielectric recovery process and forms the post-arc current, has attracted many concerns. A one-dimensional particle-in-cell model is developed to simulate the measured post-arc current in the vacuum circuit breaker in this paper. At first, the parameters of the residual plasma are estimated roughly by the waveform of the post-arc current which is taken from measurements. After that, different components of the post-arc current, which are formed by the movement of charged particles in the residual plasma, are discussed. Then, the residual plasma density is adjusted according to the proportion of electrons and ions absorbed by the post-arc anode derived from the particle-in-cell simulation. After this adjustment, the post-arc current waveform obtained from the simulation is closer to that obtained from measurements.
Zapata-Vanegas, Mario A
2014-01-01
Characterizing and contrasting the current state of affairs concerning patients' rights-associated accreditation standards in a sample of drug-addiction treatment centers in Colombia. This was mixed methodology research (i.e. descriptive and hermeneutic); a pilot sample of 21 drug-addiction treatment centers in Colombia was used for determining the current state of patients' rights accreditation standards. The possible relationship or independence between categorical variables was evaluated by using Fisher's exact test (0.05 significance level). A contrasting documentary review was made at the same time. Drug-addiction treatment centers provided more information for families (95 %) than patients (90 %) or minors (81 %). Possible barriers to gaining access for treatment were being HIV positive (29 %), being part of the LGTB population (14 %) and being female (10 %); religion and ethnicity were not seen as grounds for discrimination or treatment barriers. The patients' rights standards group coincided with Colombia's accreditation system and Joint Commission standards; however, the latter accreditation entity has made significant progress regarding a specific manual for drug-addiction treatment centers. The centers assessed in Colombia had made advances regarding accrediting patients' rights, but such standards require revision for being adapted to international developments and specific matters involved in treating addicts and the specific conditions for institutions dealing with such treatment.
Modeling Translation in Protein Synthesis with TASEP: A Tutorial and Recent Developments
NASA Astrophysics Data System (ADS)
Zia, R. K. P.; Dong, J. J.; Schmittmann, B.
2011-07-01
The phenomenon of protein synthesis has been modeled in terms of totally asymmetric simple exclusion processes (TASEP) since 1968. In this article, we provide a tutorial of the biological and mathematical aspects of this approach. We also summarize several new results, concerned with limited resources in the cell and simple estimates for the current (protein production rate) of a TASEP with inhomogeneous hopping rates, reflecting the characteristics of real genes.
2012-03-01
HSSP), the In-College Schol - arship Program (ICSP), and the Enlisted Commissioning Program (ECP) [1]. The 5 entire scholarship program is managed by...and for which they are interested in volunteering. AFROTC is currently interested in developing techniques to better allocate schol - arships and...institutions are also concerned with ensuring that they enroll the most qualified students into their programs. Camarena-Anthony [8] examines schol - arship