Developing of Environmental Education Textbook Based on Local Potencies

ERIC Educational Resources Information Center

Ilma, Silfia; Wijarini, Fitri

2017-01-01

Environmental education subject aims to form students who have the character to maintain the environment. One effort to achieve the objectives of the Environmental education subject is the local Environmental Education Textbook Based on Local Potencies. This research was aimed to produce textbook of environment-based education subject…

Advisory Encounters towards a Sustainable Farm Development-Interaction between Systems and Shared Lifeworlds

ERIC Educational Resources Information Center

Hockert, Jenny; Ljung, Magnus

2013-01-01

Purpose: The purpose of this article is to describe and critically analyse recent advisory efforts and the prevailing discourses that have affected the advisory service in Sweden over the past 15 years. The focus is on those efforts that have had a declared aim to support farmers to become more competitive and viable. We also analyse why the…

Population Growth and Economic and Social Development.

ERIC Educational Resources Information Center

Clausen, A. W.

Because evidence is clear that in many developing countries development will be postponed indefinitely unless slower population growth can be achieved soon, the international community must work together in a renewed effort to slow population growth. Assistance can be accomplished in three ways: (1) encouraging dialog aimed at forging…

Community Development in the School Workplace

ERIC Educational Resources Information Center

Brouwer, Patricia; Brekelmans, Mieke; Nieuwenhuis, Loek; Simons, Robert-Jan

2012-01-01

Purpose: The aim of this study is to explore whether and to what degree community development of teacher teams takes place and how community development comes about, that is, what community-building efforts teacher teams undertake. Design/methodology/approach: Using a multi method approach, quantitative and qualitative data were gathered from…

Basic features of the predictive tools of early warning systems for water-related natural hazards: examples for shallow landslides

NASA Astrophysics Data System (ADS)

Greco, Roberto; Pagano, Luca

2017-12-01

To manage natural risks, an increasing effort is being put in the development of early warning systems (EWS), namely, approaches facing catastrophic phenomena by timely forecasting and alarm spreading throughout exposed population. Research efforts aimed at the development and implementation of effective EWS should especially concern the definition and calibration of the interpretative model. This paper analyses the main features characterizing predictive models working in EWS by discussing their aims and their features in terms of model accuracy, evolutionary stage of the phenomenon at which the prediction is carried out and model architecture. Original classification criteria based on these features are developed throughout the paper and shown in their practical implementation through examples of flow-like landslides and earth flows, both of which are characterized by rapid evolution and quite representative of many applications of EWS.

Viewing clinical research career development through the lens of social cognitive career theory.

PubMed

Bakken, Lori L; Byars-Winston, Angela; Wang, Min-Fen

2006-02-01

Issues such as, over commitment, insufficient time, and lack of funding, threaten physicians' entry and sustainability in a research career pathway. Social cognitive career theory is presented as a conceptual framework to critically examine the limitations of the National Institutes of Health's (NIH) efforts to promote the career development of physician-scientists. Special attention is given to the unique challenges of promoting this career pathway for women and underrepresented minorities. The authors propose enhanced recommendations for the career development of physician-scientists and research questions for future studies and program development aimed at advancing the nation's efforts to promote clinical research.

Aiming for Results: Stronger Families and Healthier Children in Georgia. A Report about the Family Connection.

ERIC Educational Resources Information Center

Family Connection, Atlanta, GA.

This report presents activities of the Family Connection initiative in Georgia, whose aim is systemic change and improvement in child health, child development, family functioning, school performance, and family economic capacity. Section 1, "The National Context," illustrates how Family Connection efforts reflect a national recognition…

A change roadmap towards research paradigm in low-resource countries: retinoblastoma model in Egypt.

PubMed

Alfaar, Ahmad Samir; Nour, Radwa; Bakry, Mohamed Sabry; Kamal, Mohamed; Hassanain, Omneya; Labib, Rania M; Rashed, Wafaa M; Elzomor, Hossam; Alieldin, Adel; Taha, Hala; Zaghloul, Mohamed Saad; Ezzat, Sameera; AboElnaga, Sherif

2017-02-01

Research on childhood diseases represents a great global challenge. This challenge is maximized in both childhood cancer disciplines and developing world. In this paper, we aim at describing our institution experience in starting a structured childhood cancer research program in one of the developing countries in a short time based on philanthropic efforts. We used retinoblastoma as an example for what was conducted in this program. Starting in 2008, this program included improving clinical practice and its related supporting services besides developing new research services that both complement the clinical activities and pave the way towards creating a research foundation in the country. Results included developing hospital standard treatment protocols, developing national clinical trials, joining international consortia for childhood cancers clinical trials, developing data collection tools and real-time analytics, establishing a biobanking facility, and developing highly qualified team for conducting clinical, epidemiologic, and translational research studies. Moreover, this effort resulted in improving both clinical practice and patients' awareness nationally. This model can be used for other startup facilities that aim at finding answers for their national health problems in low-resource setting.

COASTAL EUTROPHICATION MONITORING FOR RESEARCH AND MANAGEMENT

EPA Science Inventory

The US EPA=s Atlantic Ecology Division (AED) has embarked on a multi-year research program aimed at developing empirical nitrogen load-response models for small well-flushed embayments in southern New England. This is part of a national EPA effort to develop nutrient load-respon...

Building a stakeholder network for the Indiana Climate Change Impacts Assessment

NASA Astrophysics Data System (ADS)

Dukes, J. S.; Widhalm, M.

2017-12-01

The Indiana Climate Change Impacts Assessment (IN CCIA) is a stakeholder-informed, service-driven resource developed under the coordination of the Purdue Climate Change Research Center (PCCRC) and with involvement from a diverse mix of contributors throughout the state. The IN CCIA brings together the best available climate change research into a series of reports aimed at helping Hoosiers better understand climate change-related risks so they can prepare for challenges and capitalize on opportunities. The IN CCIA development process aims to 1) increase the dialogue about climate change across the state, 2) provide Indiana decision makers with accessible, credible climate impact information, and 3) build a network of experts and stakeholders to support ongoing assessment efforts and knowledge sharing. This presentation will report on our experience with developing and maintaining a diverse stakeholder network. We will describe our efforts to connect with stakeholders before, during, and after the development of assessment reports and share the top themes that emerged from our pre-assessment inquires and other interactions.

The Collaborative Production of Meaningful Measure(ment)s: Preliminary Insights into a Work in Progress

ERIC Educational Resources Information Center

Bormann, Inka; Michelsen, Gerd

2010-01-01

This article introduces a tri-national research and development project which aims to develop indicators for the cross-sectoral and interdisciplinary educational task "education for sustainable development" (ESD). These indicators are meant to help monitor the implementation of ESD efforts in schools and institutions of higher education…

''Vulnerability'' in AIDS-Affected States: Rethinking Child Rights, Educational Institutions, and Development Paradigms

ERIC Educational Resources Information Center

Kendall, Nancy

2008-01-01

The article interrogates current international development constructs of childhood, rights, vulnerability, and schooling in light of the daily experiences of two Malawian children affected by HIV/AIDS. It aims to better understand how development efforts targeted at these children function in practice, and suggests that current development…

Objective Assessment of Listening Effort: Coregistration of Pupillometry and EEG.

PubMed

Miles, Kelly; McMahon, Catherine; Boisvert, Isabelle; Ibrahim, Ronny; de Lissa, Peter; Graham, Petra; Lyxell, Björn

2017-01-01

Listening to speech in noise is effortful, particularly for people with hearing impairment. While it is known that effort is related to a complex interplay between bottom-up and top-down processes, the cognitive and neurophysiological mechanisms contributing to effortful listening remain unknown. Therefore, a reliable physiological measure to assess effort remains elusive. This study aimed to determine whether pupil dilation and alpha power change, two physiological measures suggested to index listening effort, assess similar processes. Listening effort was manipulated by parametrically varying spectral resolution (16- and 6-channel noise vocoding) and speech reception thresholds (SRT; 50% and 80%) while 19 young, normal-hearing adults performed a speech recognition task in noise. Results of off-line sentence scoring showed discrepancies between the target SRTs and the true performance obtained during the speech recognition task. For example, in the SRT80% condition, participants scored an average of 64.7%. Participants' true performance levels were therefore used for subsequent statistical modelling. Results showed that both measures appeared to be sensitive to changes in spectral resolution (channel vocoding), while pupil dilation only was also significantly related to their true performance levels (%) and task accuracy (i.e., whether the response was correctly or partially recalled). The two measures were not correlated, suggesting they each may reflect different cognitive processes involved in listening effort. This combination of findings contributes to a growing body of research aiming to develop an objective measure of listening effort.

Preventing a Continuum of Disordered Eating: Going beyond the Individual

ERIC Educational Resources Information Center

Russell-Mayhew, Shelly

2007-01-01

Efforts aimed at the prevention of eating disorders need to consider the context within which these disorders develop and aim to promote not only healthy eating and physical activity but also address mental health factors, such as body image. Exploring the relationship between body image and eating disorders will provide a foundation and further…

Identifying Key Early Literacy and School Readiness Issues: Exploring a Strategy for Assessing Community Needs

ERIC Educational Resources Information Center

Weigel, Daniel J.; Martin, Sally S.

2006-01-01

Much effort has been expended in developing intervention programs to help improve the early literacy and school readiness skills of young children. This article presents the results of a needs assessment project aimed at identifying priorities for community intervention programs aimed at ensuring that young children enter school ready to learn. A…

Developing and Implementing Monitoring and Evaluation Methods in the New Era of Expanded Care and Treatment of HIV/AIDS

ERIC Educational Resources Information Center

Wolf, R. Cameron; Bicego, George; Marconi, Katherine; Bessinger, Ruth; van Praag, Eric; Noriega-Minichiello, Shanti; Pappas, Gregory; Fronczak, Nancy; Peersman, Greet; Fiorentino, Renee K.; Rugg, Deborah; Novak, John

2004-01-01

The sharp rise in the HIV/AIDS burden worldwide has elicited calls for increased efforts to combat the spread and impact of HIV/AIDS. Efforts must continue with the aim to decrease new infections. At the same time, care and treatment services for those already infected can lead to longer, productive lives, thereby minimizing negative effects on…

Gender and theory of mind in preschoolers' group effort: evidence for timing differences behind children's earliest social loafing.

PubMed

Thompson, R Bruce; Thornton, Bill

2014-01-01

This study explored mental state reasoning within the context of group effort and possible differences in development between boys and girls. Preschool children (59 girls, 47 boys) were assessed for theory of mind (ToM) ability using classic false belief tests. Children participated in group effort conditions that alternated from one condition, where individual effort was transparent and obvious, to one where individual effort remained anonymous. The aim was to investigate if emergent mental state reasoning, after controlling for age, was associated with the well-known phenomenon of reduced effort in group tasks ("social loafing"). Girls had slightly higher ToM scores and social loafing than boys. Hierarchical regression, controlling for age, indicated that understanding of others' false beliefs uniquely predicted social loafing and interacted weakly with gender status.

NASA photovoltaic research and technology

NASA Technical Reports Server (NTRS)

Flood, Dennis J.

1988-01-01

NASA photovoltaic R and D efforts address future Agency space mission needs through a comprehensive, integrated program. Activities range from fundamental studies of materials and devices to technology demonstrations of prototype hardware. The program aims to develop and apply an improved understanding of photovoltaic energy conversion devices and systems that will increase the performance, reduce the mass, and extend the lifetime of photovoltaic arrays for use in space. To that end, there are efforts aimed at improving cell efficiency, reducing the effects of space particulate radiation damage (primarily electrons and protons), developing ultralightweight cells, and developing advanced ray component technology for high efficiency concentrator arrays and high performance, ultralightweight arrays. Current goals that have been quantified for the program are to develop cell and array technology capable of achieving 300 watts/kg for future missions for which mass is a critical factor, or 300 watts/sq m for future missions for which array size is a major driver (i.e., Space Station). A third important goal is to develop cell and array technology which will survive the GEO space radiation environment for at least 10 years.

Increasing Pupil Physical Activity: A Comprehensive Professional Development Effort

ERIC Educational Resources Information Center

Kulinna, Pamela Hodges

2012-01-01

Study aim: To determine if pupil physical activity and Body Mass Index classifications maintained or improved after a one-year professional development program involving both classroom and physical education teachers. Guskey's model of teacher change guided this study. Material and methods: Indigenous children from ten schools (N = 320) in grades…

Children & Race.

ERIC Educational Resources Information Center

Milner, David

The major aims of this book are to provide an account of racial attitude development in young children and to describe the effects of racism on the development of black children, specifically in the United Kingdom. The book draws freely on American and British research in an effort to illuminate the British experience. The first two chapters…

Evaluating the Design and Development of an Adaptive E-Tutorial Module: A Rasch-Measurement Approach

ERIC Educational Resources Information Center

Barefah, Allaa; McKay, Elspeth

2016-01-01

Courseware designers aim to innovate information communications technology (ICT) tools to increase learning experiences, spending many hours developing eLearning programmes. This effort gives rise to a dynamic technological pedagogical environment. However, it is difficult to recognise whether these online programmes reflect an instructional…

Reaching Out: IDRC-HDFS Research Network (India). Final Report.

ERIC Educational Resources Information Center

Saraswathi, T. S.; And Others

This report documents the activities of the Research Network, a coordinated effort of the International Development Research Center (IDRC) and the Human Development and Family Studies (HDFS) Department of Baroda University (India) during the period January 1990 to June 1993. The Research Network aimed to establish a network of consultative…

Case-Based Long-Term Professional Development of Science Teachers

ERIC Educational Resources Information Center

Dori, Yehudit J.; Herscovitz, Orit

2005-01-01

Reform efforts are often unsuccessful because they failed to understand that teachers play a key role in making educational reforms successful. This paper describes a long-term teacher professional development (PD) program aimed at educating and training teachers to teach interdisciplinary topics using case-based method in science. The research…

Anticipated emotions and effort allocation in weight goal striving.

PubMed

Nelissen, Rob M A; de Vet, Emely; Zeelenberg, Marcel

2011-02-01

This study aimed to investigate the influence of anticipated emotions on preventive health behaviour if specified at the level of behavioural outcomes. Consistent with predictions from a recently developed model of goal pursuit, we hypothesized that the impact of emotions on effort levels depended on the perceived proximity to the goal. Participants with weight-loss intentions were randomly selected from an Internet panel and completed questionnaires at three points in time, baseline (T1; N= 725), 2 weeks later at T2 (N= 582) and again 2 months later at T3 (N= 528). Questionnaires assessed anticipated emotions (at T1) and experienced emotions (at T2) towards goal attainment and non-attainment. Goal proximity, goal desirability, and effort levels in striving for weight loss were assessed at both T1 and T2. Current and target weights were reported at all three assessments. In line with predictions, we found that negative anticipated emotions towards goal non-attainment resulted in increased effort but only if people perceived themselves in close proximity to their goal. Effort, in turn, predicted weight loss and goal achievement. The current data bear important practical implications as they identify anticipated emotions as targets of behaviour change interventions aimed to stimulate effort in striving for broad, health-related goals like weight loss. ©2010 The British Psychological Society.

Relative-Change Theory: Examining the Impact of Patriarchy, Paternalism, and Poverty on the Education of Women in Kenya

ERIC Educational Resources Information Center

Omwami, Edith Mukudi

2011-01-01

Forty-five years have passed since Kenya gained independence and almost 30 years since the feminist revolution ushered in a global gender and development agenda. While Kenya's development agenda had a functionalist orientation aimed at modernisation, the outcome of efforts to promote education development cannot be understood without an…

Assessing Intercultural Competence as a Result of Internationalization at Home Efforts: A Case Study From the Nightingale Mentoring Program

ERIC Educational Resources Information Center

Prieto-Flores, Òscar; Feu, Jordi; Casademont, Xavier

2016-01-01

In the last decades, many higher education institutions have developed practices of internationalization of curricula aiming at developing intercultural competences among the non-mobile majority of students. Some of them have developed service-learning activities focusing on working with underserved communities from different cultures. This…

Case Study of Science Teachers' Professional Development in Saudi Arabia: Challenges and Improvements

ERIC Educational Resources Information Center

Alshehry, Amel

2018-01-01

Professional development has a major role in addressing the skill gaps of teachers. Recently, much effort has been focused on improving teaching practices in Saudi Arabia. Here we aim to determine Saudi teachers professional development needs in the higher educational system. We also focus on skill needs, training programs, factors affecting…

Perspective of Game Theory in Education for Sustainable Development

ERIC Educational Resources Information Center

Ahrens, A.; Zascerinska, J.

2012-01-01

The sustainable development of society has attracted a lot of research efforts. A strategic aspect to the society's evolution is introduced by the game theory (Fernandez, 2011, p. 1). The research question is as follows: how to organize the process of teaching and learning in education for sustainable development? The aim of the research is to…

ENVIRONMENTALLY-BENIGN MULTIPHASE CATALYSIS. (R826034)

EPA Science Inventory

Environmental concerns stemming from the use of conventional solvents and from hazardous waste generation have propelled research efforts aimed at developing benign chemical processing techniques that either eliminate or significantly mitigate pollution at the source. This pap...

Establishment of a Bioenergy-Focused Microalgae Strain Collection Using Rapid, High-Throughput Methodologies: Cooperative Research and Development Final Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pienkos, Philip T.

2013-11-01

This project is part of the overall effort by and among NREL, Colorado State University, University of Colorado, and Colorado School of Mines known as the Colorado Center for Biorefining and Biofuels. This is part of a larger statewide effort provided for in House Bill 06-1322, establishing a Colorado Collaboratory that envisions these four institutions working together as part of the state'senergy plan. This individual project with Colorado School of Mines is the first of many envisioned in this overall effort. The project focuses on development of high throughput procedures aimed at rapidly isolating and purifying novel microalgal strains (specificallymore » green alga and diatoms) from water samples obtained from unique aquatic environments.« less

The Global Education Agenda and the Delivery of Aid to Pacific Education

ERIC Educational Resources Information Center

Coxon, Eve; Munce, Karen

2008-01-01

In recent years the international development community's concern to redress the apparent failure of half a century of "development" efforts, has given rise to a number of global initiatives aimed at both reducing worldwide poverty and enhancing international security. One outcome of these initiatives has been a refocusing on the…

Design for a Study of American Youth.

ERIC Educational Resources Information Center

Flanagan, John C.; And Others

Project TALENT is a large-scale, long-range educational research effort aimed at developing methods for the identification, development, and utilization of human talents, which has involved some 440,000 students in 1,353 public, private, and parochial secondary schools in all parts of the country. Data collected through teacher-administered tests,…

Development of Independence among Future Primary School Teachers by Applying Interactive Learning Methods

ERIC Educational Resources Information Center

Rotova, Natalia Alexandrovna

2018-01-01

The necessity to develop independence among future primary school teachers during the process of studying in higher education institutions is substantiated. The essentials of independence notion are disclosed as efforts of students aimed at reaching the goals single-handedly. The results of the ascertaining experiment on defining the level of…

Examining the Technology Integration Planning Cycle Model of Professional Development to Support Teachers' Instructional Practices

ERIC Educational Resources Information Center

Hutchison, Amy C.; Woodward, Lindsay

2018-01-01

Background: Presently, models of professional development aimed at supporting teachers' technology integration efforts are often short and decontextualized. With many schools across the country utilizing standards that require students to engage with digital tools, a situative model that supports building teachers' knowledge within their…

Sustainable Landscapes Assessment for the Philippines

Treesearch

Oliver Agoncillo; Jennifer Conje; Susan Cordell; James Halperin; Roopa Karia; Beth Lebow

2011-01-01

As part of their development of a new Country Development Strategy, and with potential for incoming Sustainable Landscapes funding, USAID/Philippines commissioned the U.S. Forest Service to work with them on an assessment of efforts aimed at Reducing Emissions from Deforestation and Forest Degradation (REDD+) in the Philippines, including the role of conservation,...

Development and Experiment in College Teaching, No. 7.

ERIC Educational Resources Information Center

Committee on Institutional Cooperation.

This report comprises a collection of summaries of exploratory efforts by college professors at the Committee on Institutional Cooperation member institutions to develop new and better ways of teaching. Usually these are local experiments aimed at improving the conditions for learning in a specific subject-matter area, but many of the procedures…

Guide to Working with Model Providers.

ERIC Educational Resources Information Center

Walter, Katie; Hassel, Bryan C.

Often a central feature of a school's improvement efforts is the adoption of a Comprehensive School Reform (CSR) model, an externally developed research-based design for school improvement. Adopting a model is only the first step in CSR. Another important step is forging partnerships with developers of CSR models. This guide aims to help schools…

Superconducting Meissner Effect Bearings for Cryogenic Turbomachines

DTIC Science & Technology

1993-05-01

Maximum 200 words) This report describes the second year efforts to develop a Meissner bearing system for miniature cryogenic turboexpanders used in... Turboexpander ....................................................................... 6 4.3. Task 7-Management and Reporting...The program is aimed at the development of a Meissner bearing system for miniature cryogenic turboexpanders used in Brayton cycle cryocoolers. "TIM

DAS photonics developments for analogue and digital photonic links for intra-satellite communications

NASA Astrophysics Data System (ADS)

Blasco, Julián.; Rico, Eloy; Genovard, Pablo; Sáez, Cristina; Navasquillo, Olga; Martí, Javier

2017-11-01

During past years, special efforts have been invested to develop optical links, both digital and analogue, for space applications, such as reference signal distribution or digital communication cables. The aim of this paper is to present the current DAS developments for these applications as well as future work to increase TRL levels and flight opportunities.

A Military-Centered Approach to Neuroprotection for Traumatic Brain Injury

PubMed Central

Shear, Deborah A.; Tortella, Frank C.

2013-01-01

Studies in animals show that many compounds and therapeutics have the potential to greatly reduce the morbidity and post-injury clinical sequela for soldiers experiencing TBI. However, to date there are no FDA approved drugs for the treatment of TBI. In fact, expert opinion suggests that combination therapies will be necessary to treat any stage of TBI recovery. Our approach to this research effort is to conduct comprehensive pre-clinical neuroprotection studies in military-relevant animal models of TBI using the most promising neuroprotective agents. In addition, emerging efforts incorporating novel treatment strategies such as stem cell based therapies and alternative therapeutic approaches will be discussed. The development of a non-surgical, non-invasive brain injury therapeutic clearly addresses a major, unresolved medical problem for the Combat Casualty Care Research Program. Since drug discovery is too expensive to be pursued by DOD in the TBI arena, this effort capitalizes on partnerships with the Private Sector (Pharmaceutical Companies) and academic collaborations (Operation Brain Trauma Therapy Consortium) to study therapies already under advanced development. Candidate therapies selected for research include drugs that are aimed at reducing the acute and delayed effects of the traumatic incident, stem cell therapies aimed at brain repair, and selective brain cooling to stabilize cerebral metabolism. Each of these efforts can also focus on combination therapies targeting multiple mechanisms of neuronal injury. PMID:23781213

Advanced public transportation systems : evaluation guidelines

DOT National Transportation Integrated Search

1994-01-01

The Federal Transit Administration has developed the Advanced Public Transportation Systems (APTS) Program which is an integral part of the overall U.S. DOT Intelligent Vehicle Highway Systems (IVHS) effort. A major aim of the APTS Program is to prom...

ENDOCRINE DISRUPTORS: LESSONS LEARNED

EPA Science Inventory

For more than ten years, major international efforts have been aimed at understanding the mechanism and extent of endocrine disruption in experimental models, wildlife, and people; its occurrence in the real world; and in developing tools for screening and prediction of risk. Mu...

State-Level Reforms That Support College-Level Program Changes in North Carolina

ERIC Educational Resources Information Center

Bowling, R. Edward; Morrissey, Sharon; Fouts, George M.

2014-01-01

This chapter describes the concurrent reforms occurring in North Carolina--both campus-level changes focused on such issues as developing structured programs of study and state-level reforms aimed at supporting the campus efforts.

To boost or to CRUNCH? Effect of effortful encoding on episodic memory in older adults is dependent on executive functioning

PubMed Central

Fu, Li; Maes, Joseph H. R.; Kessels, Roy P. C.; Daselaar, Sander M.

2017-01-01

It is essential to develop effective interventions aimed at ameliorating age-related cognitive decline. Previous studies found that effortful encoding benefits episodic memory in older adults. However, to date it is unclear whether this benefit is different for individuals with strong versus weak executive functioning (EF). Fifty-one older adults were recruited and divided into low (N = 26) and high (N = 25) functioning groups, based on their EF capacity. All participants performed a semantic and a perceptual incidental encoding task. Each encoding task was performed under four difficulty levels to establish different effort levels. Encoding was followed by a recognition task. Results showed that the high EF group benefitted from increased effort in both tasks. However, the low EF group only showed a beneficial effect under low levels of effort. Results are consistent with the Compensation-Related Utilization of Neural Circuits Hypothesis (CRUNCH) and suggest that future research directed at developing efficient memory strategies to reduce negative cognitive aging effects should take individual cognitive differences among older adults into account, such as differences in EF. PMID:28328979

Development of a conceptual framework toward an integrated transportation system (continued).

DOT National Transportation Integrated Search

2011-07-01

As a continuing effort documented in the first phase project UMAR19-13, this research focuses : on the design of a prototype application under the framework toward an Integrated : Transportation System. More specifically, this research aims at improv...

CURRENT CHALLENGES ON ENDOCRINE DISRUPTORS

EPA Science Inventory

For over ten years, major international efforts have been aimed at understanding the mechanism and extent of endocrine disruption in experimental models, wildlife, and people; the occurrence of this in the real world and in developing tools for screening and prediction of risk. ...

An accurate binding interaction model in de novo computational protein design of interactions: if you build it, they will bind.

PubMed

London, Nir; Ambroggio, Xavier

2014-02-01

Computational protein design efforts aim to create novel proteins and functions in an automated manner and, in the process, these efforts shed light on the factors shaping natural proteins. The focus of these efforts has progressed from the interior of proteins to their surface and the design of functions, such as binding or catalysis. Here we examine progress in the development of robust methods for the computational design of non-natural interactions between proteins and molecular targets such as other proteins or small molecules. This problem is referred to as the de novo computational design of interactions. Recent successful efforts in de novo enzyme design and the de novo design of protein-protein interactions open a path towards solving this problem. We examine the common themes in these efforts, and review recent studies aimed at understanding the nature of successes and failures in the de novo computational design of interactions. While several approaches culminated in success, the use of a well-defined structural model for a specific binding interaction in particular has emerged as a key strategy for a successful design, and is therefore reviewed with special consideration. Copyright © 2013 Elsevier Inc. All rights reserved.

Undertaking Individual Transdisciplinary PhD Research for Sustainable Development: Case Studies from South Africa

ERIC Educational Resources Information Center

van Breda, John; Musango, Josephine; Brent, Alan

2016-01-01

Purpose: This paper aims to improve the understanding of individual transdisciplinary PhD research in a developing country context, focusing on three individual PhD case studies in South Africa. Design/Methodology/Approach: Multiple-case method was used, and three completed transdisciplinary PhD research efforts undertaken at the Stellenbosch…

Games as a Platform for Student Participation in Authentic Scientific Research

ERIC Educational Resources Information Center

Magnussen, Rikke; Hansen, Sidse Damgaard; Planke, Tilo; Sherson, Jacob Friis

2014-01-01

This paper presents results from the design and testing of an educational version of Quantum Moves, a Scientific Discovery Game that allows players to help solve authentic scientific challenges in the effort to develop a quantum computer. The primary aim of developing a game-based platform for student-research collaboration is to investigate if…

Does Mother Tongue Education Support Development of Environmental Literacy in Turkey? An Analysis of Turkish Course Books

ERIC Educational Resources Information Center

Uyar, Yusuf; Ensar, Ferhat

2016-01-01

Development of environmental literacy needs an interdisciplinary effort. Especially language classes, with environment related texts, have potential to support environmental literacy. In this research it is aimed to analyze the Turkish language course books in terms of components of environmental literacy. To this end, four Turkish course books…

The Development of improved willow clones for eastern North America

Treesearch

R. F. Kopp; L. B. Smart; C. A. Maynard; J. G. Isebrands; G. A. Tuskan; L. P. Abrahamson

2001-01-01

Efforts aimed at genetic improvement of Salix are increasing in North America.Most of these are directed towards developing improved clones for biomass production, phytoremediation, nutrient filters, and stream bank stabilization in the Northeast and North-central United States. Native species are of primary interest, but a small number of clones containing non-native...

Developing a Mobile Application "Educational Process Remote Management System" on the Android Operating System

ERIC Educational Resources Information Center

Abildinova, Gulmira M.; Alzhanov, Aitugan K.; Ospanova, Nazira N.; Taybaldieva, Zhymatay; Baigojanova, Dametken S.; Pashovkin, Nikita O.

2016-01-01

Nowadays, when there is a need to introduce various innovations into the educational process, most efforts are aimed at simplifying the learning process. To that end, electronic textbooks, testing systems and other software is being developed. Most of them are intended to run on personal computers with limited mobility. Smart education is…

What Motivates Biology Instructors to Engage and Persist in Teaching Professional Development?

ERIC Educational Resources Information Center

McCourt, Jill S.; Andrews, Tessa C.; Knight, Jennifer K.; Merrill, John E.; Nehm, Ross H.; Pelletreau, Karen N.; Prevost, Luanna B.; Smith, Michelle K.; Urban-Lurain, Mark; Lemons, Paula P.

2017-01-01

We conducted a study of 19 biology instructors participating in small, local groups at six research-intensive universities connected to the Automated Analysis of Constructed Response (AACR) project (www.msu.edu/~aacr). Our aim was to uncover participants' motivation to persist in a long-term teaching professional development effort, a topic that…

Leveraging University Research to Serve Economic Development: An Analysis of Policy Dynamics in and across Three US States

ERIC Educational Resources Information Center

Warshaw, Jarrett B.; Hearn, James C.

2014-01-01

As economic competition becomes more global and knowledge-based, US states have independently pursued initiatives in research and development (R&D) and science and technology (S&T). Policy efforts often entwine government, universities, and industry, aiming to stimulate socially optimal levels of innovation and economic growth.…

The Right to Education from Proclamation to Achievement 1948-1968.

ERIC Educational Resources Information Center

Francois, Louis

The aim of this booklet is to describe and explain efforts over the past twenty years for the right to education in the world's nations. The theme focuses upon an attempt to actualize the ideals in the Universal Declaration of Human Rights which concern and affect universal education in developing as well as developed countries. Eleven chapters…

Millennium Development Goal 5 and adolescents: looking back, moving forward

PubMed Central

Vogel, Joshua P; Pileggi-Castro, Cynthia; Chandra-Mouli, Venkatraman; Pileggi, Vicky Nogueira; Souza, João Paulo; Chou, Doris; Say, Lale

2015-01-01

Since the Millennium Declaration in 2000, unprecedented progress has been made in the reduction of global maternal mortality. Millennium Development Goal 5 (MDG 5; improving maternal health) includes two primary targets, 5A and 5B. Target 5A aimed for a 75% reduction in the global maternal mortality ratio (MMR), and 5B aimed to achieve universal access to reproductive health. Globally, maternal mortality since 1990 has nearly halved and access to reproductive health services in developing countries has substantially improved. In setting goals and targets for the post-MDG era, the global maternal health community has recognised that ultimate goal of ending preventable maternal mortality is now within reach. The new target of a global MMR of <70 deaths per 100 000 live births by 2030 is ambitious, yet achievable and to reach this target a significantly increased effort to promote and ensure universal, equitable access to reproductive, maternal and newborn services for all women and adolescents will be required. In this article, as we reflect on patterns, trends and determinants of maternal mortality, morbidity and other key MDG5 indicators among adolescents, we aim to highlight the importance of promoting and protecting the sexual and reproductive health and rights of adolescents as part of renewed global efforts to end preventable maternal mortality. PMID:25613967

Health Reform: A Community Experience Using Design Research as a Guide

PubMed Central

Severson, Mary A.; Wood, Douglas L.; Chastain, Christine N.; Lee, Laura G.; Rees, Adam C.; Agerter, David C.; Holtz, Carol P.; Broers, Joan K.; Savoleinen, Kimberly H.; Spurrier, Barbara R.; LaRusso, Nicholas F.

2011-01-01

Meaningful health reform in the United States must improve the health of the population while lowering costs. In an effort to provide a framework for doing so, the Institute of Health Care Improvement created the triple aim, which encompasses the goals of (1) improving individual health and experience with the health care system, (2) improving population health, and (3) decreasing the rate of per capita health care costs. Current reform efforts have focused on the development of Patient-Centered Medical Homes (an innovative team-based model of care that facilitates a partnership between the patient’s personal physician coordinating care throughout a patient’s lifetime to maximize health outcomes), but these relatively narrow efforts are focused on office practice and payment methods and are not generally oriented toward community needs. We sought to apply design research in assessing a community opportunity to apply the triple aim as a strategy to transform health care delivery. Mixed methodology provides greater insight into the unexpressed health needs of individuals and into the creation of delivery systems more likely to achieve the triple aim. In a small, midwestern town, a mixed methods approach was used to assess community health needs to facilitate design and implementation of care delivery systems. The research findings suggest that health system design concepts should focus on the creation of health, not health care; foster simplicity; create nurturing relationships; eliminate user fear; and contain costs. These observations can be helpful to health care professionals who are developing new methods of care delivery and policymakers and payers contemplating new payment systems to achieve the goals of the triple aim. PMID:21964174

Pointing and Tracking Concepts for Deep Space Missions

NASA Technical Reports Server (NTRS)

Alexander, J. W.; Lee, S.; Chen, C.

2000-01-01

This paper summarizes part of a FY1998 effort on the design and development of an optical communications (Opcomm) subsystem for the Advanced Deep Space System Development (ADSSD) Project. This study was funded by the JPL X2000 program to develop an optical communications (Opcomm) subsystem for use in future planetary missions. The goal of this development effort was aimed at providing prototype hardware with the capability of performing uplink, downlink, and ranging functions from deep space distances. Such a system was envisioned to support future deep space missions in the Outer Planets/Solar Probe (OPSP) mission set such as the Pluto express and Europa orbiter by providing a significant enhancement of data return capability. A study effort was initiated to develop a flyable engineering model optical terminal to support the proposed Europa Orbiter mission - as either the prime telecom subsystem or for mission augmentation. The design concept was to extend the prototype lasercom terminal development effort currently conducted by JPL's Optical Communications Group. The subsystem would track the sun illuminated Earth at Europa and farther distances for pointing reference. During the course of the study, a number of challenging issues were found. These included thermo-mechanical distortion, straylight control, and pointing. This paper focuses on the pointing aspects required to locate and direct a laser beam from a spacecraft (S/C) near Jupiter to a receiving station on Earth.

Helwan University Project Developing Primary School Pupils' Abilities and Skills at Some Egyptian Underprivileged Areas (Slums). (Field Study)

ERIC Educational Resources Information Center

El-Tayeb, Mahmoud N.; El Nashar, Mohamed; Zeid, Mai M.; El-Sayed, Magda; Ramadan, Mohamed A.; Hamdi, Safia M.; El-Affy, Nabila; Ebeid, Amina K.; El-Marasi, Sonia S.; Abou-Elmahty, Maher

2010-01-01

Through directing concerted efforts and educational services of seven Faculties of Helwan University towards socially underprivileged pupils in slum areas (EL-Marg area in big Cairo) this research project had two main aims: firstly, modifying a set of arbitrary behaviors of those pupils, in a trial to develop some behavior skills associated with…

Development and application of a probabilistic method for wildfire suppression cost modeling

Treesearch

Matthew P. Thompson; Jessica R. Haas; Mark A. Finney; David E. Calkin; Michael S. Hand; Mark J. Browne; Martin Halek; Karen C. Short; Isaac C. Grenfell

2015-01-01

Wildfire activity and escalating suppression costs continue to threaten the financial health of federal land management agencies. In order to minimize and effectively manage the cost of financial risk, agencies need the ability to quantify that risk. A fundamental aim of this research effort, therefore, is to develop a process for generating risk-based metrics for...

Sustainable Development Policies as Indicators and Pre-Conditions for Sustainability Efforts at Universities: Fact or Fiction?

ERIC Educational Resources Information Center

Leal Filho, Walter; Brandli, Luciana Londero; Becker, Deisi; Skanavis, Constantina; Kounani, Aristea; Sardi, Chrysoula; Papaioannidou, Dimitra; Paço, Arminda; Azeiteiro, Ulisses; de Sousa, Luiza Olim; Raath, Schalk; Pretorius, Rudi Wessel; Shiel, Christine; Vargas, Valeria; Trencher, Gregory; Marans, Robert W.

2018-01-01

Purpose: There is a widely held belief that sustainable development (SD) policies are essential for universities to successfully engage in matters related to sustainability, and are an indicator of the extent to which they are active in this field. This paper aims to examine the evidence which currently exists to support this assumption. It…

Promoting Good Mental Health from Primary to Early Secondary Grades--Preventive Interventions in Schools.

ERIC Educational Resources Information Center

Jason, Leonard A.; Ferone, Louise

1980-01-01

The paper describes a four-year research effort aimed at developing preventive educational interventions for children with behavior problems in inner city schools. The implications of switching the emphasis from early secondary to primary preventive programs are discussed. (Author)

Malaria vaccine development and how external forces shape it: an overview.

PubMed

Lorenz, Veronique; Karanis, Gabriele; Karanis, Panagiotis

2014-06-30

The aim of this paper is to analyse the current status and scientific value of malaria vaccine approaches and to provide a realistic prognosis for future developments. We systematically review previous approaches to malaria vaccination, address how vaccine efforts have developed, how this issue may be fixed, and how external forces shape vaccine development. Our analysis provides significant information on the various aspects and on the external factors that shape malaria vaccine development and reveal the importance of vaccine development in our society.

New Approaches to HSCT Multidisciplinary Design and Optimization

NASA Technical Reports Server (NTRS)

Schrage, D. P.; Craig, J. I.; Fulton, R. E.; Mistree, F.

1996-01-01

The successful development of a capable and economically viable high speed civil transport (HSCT) is perhaps one of the most challenging tasks in aeronautics for the next two decades. At its heart it is fundamentally the design of a complex engineered system that has significant societal, environmental and political impacts. As such it presents a formidable challenge to all areas of aeronautics, and it is therefore a particularly appropriate subject for research in multidisciplinary design and optimization (MDO). In fact, it is starkly clear that without the availability of powerful and versatile multidisciplinary design, analysis and optimization methods, the design, construction and operation of im HSCT simply cannot be achieved. The present research project is focused on the development and evaluation of MDO methods that, while broader and more general in scope, are particularly appropriate to the HSCT design problem. The research aims to not only develop the basic methods but also to apply them to relevant examples from the NASA HSCT R&D effort. The research involves a three year effort aimed first at the HSCT MDO problem description, next the development of the problem, and finally a solution to a significant portion of the problem.

Overview of NASA's Thermal Control System Development for Exploration Project

NASA Technical Reports Server (NTRS)

Stephan, Ryan A.

2011-01-01

The now-cancelled Constellation Program included the Orion, Altair, and Lunar Surface Systems project offices. The first two elements, Orion and Altair, were planned to be manned space vehicles while the third element was much more diverse and included several sub-elements. Among other things, these sub-elements were Rovers and a Lunar Habitat. The planned missions involving these systems and vehicles included several risks and design challenges. Due to the unique thermal operating environment, many of these risks and challenges were associated with the vehicles thermal control system. NASA s Exploration Technology Development Program (ETDP) consisted of various technology development projects. The project chartered with mitigating the aforementioned thermal risks and design challenges was the Thermal Control System Development for Exploration Project. These risks and design challenges were being addressed through a rigorous technology development process that was planned to culminate with an integrated thermal control system test. Although the technologies being developed were originally aimed towards mitigating specific Constellation risks, the technology development process is being continued within a new program. This continued effort is justified by the fact that many of the technologies are generically applicable to future spacecraft thermal control systems. The current paper summarizes the development efforts being performed by the technology development project. The development efforts involve heat acquisition and heat rejection hardware including radiators, heat exchangers, and evaporators. The project has also been developing advanced phase change material heat sinks and performing a material compatibility assessment for a promising thermal control system working fluid. The to-date progress and lessons-learned from these development efforts will be discussed throughout the paper.

Effort-reward imbalance and burnout among German nurses in medical compared with psychiatric hospital settings.

PubMed

Schulz, M; Damkröger, A; Heins, C; Wehlitz, L; Löhr, M; Driessen, M; Behrens, J; Wingenfeld, K

2009-04-01

The aim of this study was to investigate whether nurses' efforts and rewards, as well as the effort-reward imbalance (ERI) and burnout, differ between subjects working in psychiatric vs. medical hospitals and between nurses under education and examined nurses respectively. Furthermore, the relationship between ERI and burnout was evaluated. Nursing is associated with high levels of emotional strain and heavy workloads. Burnout and a negative ERI can result in high absenteeism and turnover and have been identified as reasons why nurses leave their profession. In the last decade, working conditions of the nursing profession have changed in Germany, but somatic and psychiatric hospitals developed in different ways. This development may lead to different profiles. A sample of 389 nurses (78.8% female) in four German hospitals was investigated. A total of 147 nurses worked in psychiatric hospitals and 236 nurses worked in medical (somatic) hospitals. Fifty participants were still under education. The Effort-Reward Imbalance Inventory measures effort, reward and overcommitment at job and provides an imbalance score between effort and reward. The Maslach Burnout Inventory with the subscales, emotional exhaustion, lack of accomplishment and depersonalization, was also used. Nurses working in medical hospitals reported more burnout and had higher ERI scores. Subjects under education were comparable to examined nurses in terms of burnout but had lower ERI scores. Multiple regression analyses showed all ERI scales to be significant predictors for emotional exhaustion, while age, field of work and educational status further predict effort or ERI respectively. At present, the working situation of nurses in different settings appears to be characterized by a perceived imbalance of effort and reward and is associated with a high risk of developing burnout symptoms.

Process development

NASA Technical Reports Server (NTRS)

Bickler, D. B.

1985-01-01

An overview is given of seven process development activities which were presented at this session. Pulsed excimer laser processing of photovoltaic cells was presented. A different pulsed excimer laser annealing was described using a 50 w laser. Diffusion barrier research focused on lowering the chemical reactivity of amorphous thin film on silicon. In another effort adherent and conductive films were successfully achieved. Other efforts were aimed at achieving a simultaneous front and back junction. Microwave enhanced plasma deposition experiments were performed. An updated version of the Solar Array Manufacturing Industry Costing Standards (SAMICS) was presented, along with a life cycle cost analysis of high efficiency cells. The last presentation was on the evaluation of the ethyl vinyl acetate encapsulating system.

The National Plan for Research and Development In Support of Critical Infrastructure Protection

DTIC Science & Technology

2004-01-01

vulnerabilities and highlight areas for improvement. As part of this effort, CIP &CP has cre- ated a research and development agenda aimed at improving...Infrastructure Protection Research and Development Plan 13 LONG-TERM DIRECTION PROVIDED BY THE CIP R&D PLAN The creation of a national critical...Research and Development Plan 20 Mapping to Other National R&D Plans The many R&D plans outside the direct context of CIP underway within DHS, other

Assessing Cyberbullying in Higher Education

ERIC Educational Resources Information Center

Kamali, Ali

2015-01-01

This project aims to expose information educators to various aspects of cyberbullying for the purpose of policy development in an environment of higher education. The preponderance of nation-wide research on cyberbullying is concentrated on adolescents; such efforts in college campuses are limited to individual endeavors. Cyberbullying research on…

Fission Energy and Other Sources of Energy

ERIC Educational Resources Information Center

Alfven, Hannes

1974-01-01

Discusses different forms of energy sources and basic reasons for the opposition to the use of atomic energy. Suggests that research efforts should also be aimed toward the fission technology to make it acceptable besides major research studies conducted in the development of alternative energy sources. (CC)

Keep a Focus on Meaningful Reform Efforts Instead of Political Agendas

ERIC Educational Resources Information Center

Curtis, Deborah; Bordelon, Deborah; Teitelbaum, Kenneth

2010-01-01

This article draws contrasts between useful, research-based recommendations for the further development and assessment of teacher- and leader-preparation programs and those studies aiming at total "reform" that are frequently distinguished by their questionable methods, faulty assumptions, and complete disregard for the established…

Glenn Research Center Human Research Program: Overview

NASA Technical Reports Server (NTRS)

Nall, Marsha M.; Myers, Jerry G.

2013-01-01

The NASA-Glenn Research Centers Human Research Program office supports a wide range of technology development efforts aimed at enabling extended human presence in space. This presentation provides a brief overview of the historical successes, current 2013 activities and future projects of NASA-GRCs Human Research Program.

Trait responses of invasive aquatic macrophyte congeners: colonizing diploid outperforms polyploid

USDA-ARS?s Scientific Manuscript database

Understanding traits underlying colonization and niche breadth of invasive plants is key to developing sustainable management solutions to curtail invasions at the establishment phase, when efforts are often most effective. The aim of this study was to evaluate how two invasive congeners differing i...

Component technology for stirling power converters

NASA Technical Reports Server (NTRS)

Thieme, Lanny G.

1991-01-01

NASA Lewis Research Center has organized a component technology program as part of the efforts to develop Stirling converter technology for space power applications. The Stirling Space Power Program is part of the NASA High Capacity Power Project of the Civil Space Technology Initiative (CSTI). NASA Lewis is also providing technical management for the DOE/Sandia program to develop Stirling converters for solar terrestrial power producing electricity for the utility grid. The primary contractors for the space power and solar terrestrial programs develop component technologies directly related to their goals. This Lewis component technology effort, while coordinated with the main programs, aims at longer term issues, advanced technologies, and independent assessments. An overview of work on linear alternators, engine/alternator/load interactions and controls, heat exchangers, materials, life and reliability, and bearings is presented.

Characterisation of Best Practices in the Development of Cross-Curricular Competences in Vocational Education and Training: Case Study in the Basque Country

ERIC Educational Resources Information Center

Eizagirre Sagardia, Ana; Imaz Bengoetxea, Jose Inazio; Rekalde Rodríguez, Itziar

2018-01-01

This paper presents the most important results of a research project aimed at gathering empirical evidence on current efforts to foster and develop cross-curricular competences (CCC) in Vocational Education and Training (VET) Centres located in the Basque Country (Spain). The case study research method was used, with data being gathered by means…

Hands-on Workshops Aim to Strengthen Tobacco Control Efforts in Indonesia

Cancer.gov

The Global Adult Tobacco Survey (GATS), conducted in 2011 by the Indonesian National Institute of Health Research and Development and the U.S. Center for Disease Control and Prevention, showed that more than 67% of men and almost 40% of boys aged 13-15 use tobacco.

Preservation Health Check: Monitoring Threats to Digital Repository Content

ERIC Educational Resources Information Center

Kool, Wouter; van der Werf, Titia; Lavoie, Brian

2014-01-01

The Preservation Health Check (PHC) project, undertaken as a joint effort by Open Planets Foundation (OPF) and OCLC Research, aims to evaluate the usefulness of the preservation metadata created and maintained by operational repositories for assessing basic preservation properties. The PHC project seeks to develop an implementable logic to support…

Marketing Needed to Make Universities Globally Competitive

ERIC Educational Resources Information Center

Naik, B. M.

2016-01-01

The article aims at improving the quality of higher and technical education in India to world class standard. Institutions in knowledge economy are reckoned to be the drivers of development. Indian institutions are making efforts, investing money, appointing professors, students are studying hard but due to the lack of marketing strategy, their…

An Interoperable Electronic Medical Record-Based Platform for Personalized Predictive Analytics

ERIC Educational Resources Information Center

Abedtash, Hamed

2017-01-01

Precision medicine refers to the delivering of customized treatment to patients based on their individual characteristics, and aims to reduce adverse events, improve diagnostic methods, and enhance the efficacy of therapies. Among efforts to achieve the goals of precision medicine, researchers have used observational data for developing predictive…

Intellectual Estuaries: Connecting Learning and Creativity in Programs of Advanced Academics

ERIC Educational Resources Information Center

Beghetto, Ronald A.; Kaufman, James C.

2009-01-01

Academic learning and creativity should be overlapping goals that can be simultaneously pursued in programs of advanced academics. However, efforts aimed at nurturing creativity and academic learning sometimes are represented as two related but separate paths; this separation is unnecessary and can undermine the development of creative and…

Assessing and Promoting Cultural Relativism in Students of Counseling

ERIC Educational Resources Information Center

Mcauliffe, Garrett John; Grothaus, Tim; Jensen, Margaret; Michel, Rebecca

2012-01-01

Multicultural counseling is often promoted as a core element in counselor development. As such, educational efforts aim to increase counselors' cultural relativism, or their ability to recognize their own enculturation and to appreciate the value of other cultural norms. This mixed qualitative-quantitative study explored the relationship between…

Preparing Current and Future Practitioners to Integrate Research in Real Practice Settings

ERIC Educational Resources Information Center

Thyer, Bruce A.

2015-01-01

Past efforts aimed at promoting a better integration between research and practice are reviewed. These include the empirical clinical practice movement (ECP), originating within social work; the empirically supported treatment (EST) initiative of clinical psychology; and the evidence-based practice (EBP) model developed within medicine. The…

Education for International Understanding: The Case of Ethiopia.

ERIC Educational Resources Information Center

International Bureau of Education, Paris (France).

This study reviews Ethiopia's efforts, experiences, and achievements with respect to developing education for international understanding over the past two decades in response to the United Nations recognition of the role education plays in promoting peace. It is an overture aimed at sharing ideas and experiences with all concerned for the…

MOOC Learning Experience Design: Issues and Challenges

ERIC Educational Resources Information Center

Fournier, Hélène; Kop, Rita

2015-01-01

This paper will present current work on various frameworks that are aimed at guiding the research, development, and evaluation efforts around Massive Open Online Courses (MOOCs). Initiatives and activities, including current work by the National Research Council (NRC) in the context of Learning and Performance Support Systems and MOOCs, will be…

Exploratory Practice and Soft Systems Methodology

ERIC Educational Resources Information Center

Tajino, Akira; Smith, Craig

2005-01-01

This paper aims to demonstrate that Soft Systems Methodology (SSM), a soft systems approach developed in management studies (see Checkland, 1981), can be usefully linked with Exploratory Practice (EP), a form of practitioner research for language classrooms. Some compatible SSM and EP characteristics, in tandem, could enhance continual efforts to…

Natural hazard modeling and uncertainty analysis [Chapter 2

Treesearch

Matthew Thompson; Jord J. Warmink

2017-01-01

Modeling can play a critical role in assessing and mitigating risks posed by natural hazards. These modeling efforts generally aim to characterize the occurrence, intensity, and potential consequences of natural hazards. Uncertainties surrounding the modeling process can have important implications for the development, application, evaluation, and interpretation of...

End-User Applications of Real-Time Earthquake Information in Europe

NASA Astrophysics Data System (ADS)

Cua, G. B.; Gasparini, P.; Giardini, D.; Zschau, J.; Filangieri, A. R.; Reakt Wp7 Team

2011-12-01

The primary objective of European FP7 project REAKT (Strategies and Tools for Real-Time Earthquake Risk Reduction) is to improve the efficiency of real-time earthquake risk mitigation methods and their capability of protecting structures, infrastructures, and populations. REAKT aims to address the issues of real-time earthquake hazard and response from end-to-end, with efforts directed along the full spectrum of methodology development in earthquake forecasting, earthquake early warning, and real-time vulnerability systems, through optimal decision-making, and engagement and cooperation of scientists and end users for the establishment of best practices for use of real-time information. Twelve strategic test cases/end users throughout Europe have been selected. This diverse group of applications/end users includes civil protection authorities, railway systems, hospitals, schools, industrial complexes, nuclear plants, lifeline systems, national seismic networks, and critical structures. The scale of target applications covers a wide range, from two school complexes in Naples, to individual critical structures, such as the Rion Antirion bridge in Patras, and the Fatih Sultan Mehmet bridge in Istanbul, to large complexes, such as the SINES industrial complex in Portugal and the Thessaloniki port area, to distributed lifeline and transportation networks and nuclear plants. Some end-users are interested in in-depth feasibility studies for use of real-time information and development of rapid response plans, while others intend to install real-time instrumentation and develop customized automated control systems. From the onset, REAKT scientists and end-users will work together on concept development and initial implementation efforts using the data products and decision-making methodologies developed with the goal of improving end-user risk mitigation. The aim of this scientific/end-user partnership is to ensure that scientific efforts are applicable to operational, real-world problems.

Small Groups, Big Change: Preliminary Findings from the Sparks for Change Institute

NASA Astrophysics Data System (ADS)

Kirsch, R.; Batchelor, R. L.; Habtes, S. Y.; King, B.; Crockett, J.

2017-12-01

The geoscience professoriate continues to under represent women and minorities, yet the value of diversity, both for science as well as recruiting and retaining diverse students, is well known. While there are growing numbers of early career tenure-track minority faculty, low retention rates pose a challenge for sustained diversity in the professoriate. Part of this challenge is the lack of institutional support and recognition in tenure and promotion pathways for faculty who undertake broadening participation efforts. Sparks for Change is a NSF Geoscience Opportunities for Leadership in Diversity (GOLD)-funded project that aims to change departmental culture to better value and reward inclusion and broadening participation efforts. By encouraging, recognizing, and rewarding diversity, equity, and inclusion (DEI) efforts at the department level, we aim to support and retain underrepresented minority (URM) faculty, who often disproportionately undertake these efforts, and to build more inclusive environments for faculty, staff and students alike. Sparks for Change utilizes a small group theory of change, arguing that the effort of a small group of committed individuals inside the organization is the best way to overcome the institutional inertia of academic departments that makes them resistant to change. For this effort, we propose that the ideal composition of these small groups is a junior faculty URM who is interested in DEI in the geosciences, a senior member of that same department who can lend weight to efforts and is positioned to help enact department policy, and an external broadening participation expert who can share best practices and provide accountability for the group. Eleven of these small groups, representing a range of institutions, will be brought together at the Sparks for Change Institute in Boulder, CO, in September. There they will receive leadership training on adaptive, transformative, and solidarity practices, share DEI experiences and best practices, build a community of "change agents", and develop department-specific action plans for their own institution. In this talk we will discuss our findings from the institute and highlight some of the action plans the small groups developed for changing their department.

Autonomous Operations System: Development and Application

NASA Technical Reports Server (NTRS)

Toro Medina, Jaime A.; Wilkins, Kim N.; Walker, Mark; Stahl, Gerald M.

2016-01-01

Autonomous control systems provides the ability of self-governance beyond the conventional control system. As the complexity of mechanical and electrical systems increases, there develops a natural drive for developing robust control systems to manage complicated operations. By closing the bridge between conventional automated systems to knowledge based self-awareness systems, nominal control of operations can evolve into relying on safe critical mitigation processes to support any off-nominal behavior. Current research and development efforts lead by the Autonomous Propellant Loading (APL) group at NASA Kennedy Space Center aims to improve cryogenic propellant transfer operations by developing an automated control and health monitoring system. As an integrated systems, the center aims to produce an Autonomous Operations System (AOS) capable of integrating health management operations with automated control to produce a fully autonomous system.

Synthetic antibodies: concepts, potential and practical considerations.

PubMed

Miersch, S; Sidhu, S S

2012-08-01

The last 100 years of enquiry into the fundamental basis of humoral immunity has resulted in the identification of antibodies as key molecular sentinels responsible for the in vivo surveillance, neutralization and clearance of foreign substances. Intense efforts aimed at understanding and exploiting their exquisite molecular specificity have positioned antibodies as a cornerstone supporting basic research, diagnostics and therapeutic applications [1]. More recently, efforts have aimed to circumvent the limitations of developing antibodies in animals by developing wholly in vitro techniques for designing antibodies of tailored specificity. This has been realized with the advent of synthetic antibody libraries that possess diversity outside the scope of natural immune repertoires and are thus capable of yielding specificities not otherwise attainable. This review examines the convergence of technologies that have contributed to the development of combinatorial phage-displayed antibody libraries. It further explores the practical concepts that underlie phage display, antibody diversity and the methods used in the generation of and selection from phage-displayed synthetic antibody libraries, highlighting specific applications in which design approaches gave rise to specificities that could not easily be obtained with libraries based upon natural immune repertories. Copyright © 2012 Elsevier Inc. All rights reserved.

Space industrialization: A national perspective

NASA Technical Reports Server (NTRS)

Reis, V. H.

1984-01-01

Space industrialization (or commercialization) has the potential to be a major player in America's space program. If this potential is to be realized, however, industrialization efforts must be considered within the context of the other major portions of the space program: shuttle, space station, and civil remote sensing. Further, development efforts must be based upon a sound scientific and technical understanding of the products and processes, and there must be a trained cadre of dedicated individuals willing to devote time and effort to this effort. There remain considerable risks and uncertainties. Given all this, the best path to follow would seem to be a long term, balanced commitment, emphasizing government, industry, and academia partnerships. Several points are addressed: (1) the place of space industrialization in the overall national space program; (2) the meaning of space industrialization with respect to the historic, national aims of space; and (3) specifically what is being industrialized.

Reconfigurable, Intelligently-Adaptive, Communication System, an SDR Platform

NASA Technical Reports Server (NTRS)

Roche, Rigoberto

2016-01-01

The Space Telecommunications Radio System (STRS) provides a common, consistent framework to abstract the application software from the radio platform hardware. STRS aims to reduce the cost and risk of using complex, configurable and reprogrammable radio systems across NASA missions. The Glenn Research Center (GRC) team made a software-defined radio (SDR) platform STRS compliant by adding an STRS operating environment and a field programmable gate array (FPGA) wrapper, capable of implementing each of the platforms interfaces, as well as a test waveform to exercise those interfaces. This effort serves to provide a framework toward waveform development on an STRS compliant platform to support future space communication systems for advanced exploration missions. Validated STRS compliant applications provided tested code with extensive documentation to potentially reduce risk, cost and efforts in development of space-deployable SDRs. This paper discusses the advantages of STRS, the integration of STRS onto a Reconfigurable, Intelligently-Adaptive, Communication System (RIACS) SDR platform, the sample waveform, and wrapper development efforts. The paper emphasizes the infusion of the STRS Architecture onto the RIACS platform for potential use in next generation SDRs for advance exploration missions.

Tax, price and cigarette smoking: evidence from the tobacco documents and implications for tobacco company marketing strategies

PubMed Central

Chaloupka, F; Cummings, K; Morley, C.; Horan, J.

2002-01-01

Methods: Data for this study come from tobacco industry documents contained in the Youth and Marketing database created by the Roswell Park Cancer Institute and available through http:// roswell.tobaccodocuments.org, supplemented with documents obtained from http://www.tobaccodocuments.org. Results: Tobacco company documents provide clear evidence on the impact of cigarette prices on cigarette smoking, describing how tax related and other price increases lead to significant reductions in smoking, particularly among young persons. This information was very important in developing the industry's pricing strategies, including the development of lower price branded generics and the pass through of cigarette excise tax increases, and in developing a variety of price related marketing efforts, including multi-pack discounts, couponing, and others. Conclusions: Pricing and price related promotions are among the most important marketing tools employed by tobacco companies. Future tobacco control efforts that aim to raise prices and limit price related marketing efforts are likely to be important in achieving reductions in tobacco use and the public health toll caused by tobacco. PMID:11893816

Thriving Together: Connecting Rural School Improvement and Community Development = Prosperando juntos: La conexion entre el mejoramiento de la escuela rural y el desarrollo comunitario.

ERIC Educational Resources Information Center

Boethel, Martha

Available in English or Spanish, this resource guide aims to help rural schools and communities learn ways of supporting each other so that both can thrive. Background information and basic tools are provided for starting a joint school-community development effort. Chapters contain: (1) outline of the guide and statement of beliefs about…

COLLABORATIVE RESEARCH AND DEVELOPMENT (CR&D) Delivery Order 0067: Molecular Simulations for Hydrated Polymer Fuel Membranes

DTIC Science & Technology

2007-11-01

proton transfer. 1. INTRODUCTION While polymer electrolyte membrane fuel cells ( PEMFCs ) hold out the possibility for providing several important...Among the broader aims of the research is to develop PEMFC systems which can operate at higher temperatures than presently achievable while still...efforts have provided insight into the mechanisms which enable proton conduction in PEMFCs . Hydrated membranes are two-phase systems, an

The harvested side of edges: effect of retained forests on the re-establishement of biodiversity in adjacent harvested areas

Treesearch

Susan C. Baker; Thomas A. Spies; Timothy J. Wardlaw; Jayne Balmer; Jerry F. Franklin

2013-01-01

Most silvicultural methods have been developed with the principal aim of ensuring adequate regeneration of commercial tree species after harvesting. Much less effort has been directed towards developing methods that benefit the re-establishment of all forest biodiversity. The concept of ‘forest influence’ relates the probability of species re-establishment to the...

Measuring a hospital's ability to improve.

PubMed

Meurer, Steven J; Counte, Michael A; Rubio, Doris M; Arrington, Barbara

2004-01-01

The aim of this study was to test whether a recently developed measure of Continuous Quality Improvement (CQI) implementation can provide health care researchers and administrators with a tool to assist in understanding and with developing an appropriate structure for improvement efforts in hospitals. Two hundred respondents from 40 Missouri hospitals completed a 28-item survey addressing 8 domains of CQI. Overall, hospital scores showed low implementation of a structure that supports improvement efforts. All survey domains showed acceptable psychometric results. Leadership proved to be the most important domain of CQI because it differentiated well between all levels of the scale. Because of its ease of administration and analysis, and its reliability, validity, and level differentiation results, the researchers recommend the widespread use of this tool to understand and develop a hospital's organizational structure to support improvement activities.

Electronic health records approaches and challenges: a comparison between Malaysia and four East Asian countries.

PubMed

Abd Ghani, Mohd Khanapi; Bali, Rajeev K; Naguib, Raouf N G; Marshall, Ian M

2008-01-01

An integrated Lifetime Health Record (LHR) is fundamental for achieving seamless and continuous access to patient medical information and for the continuum of care. However, the aim has not yet been fully realised. The efforts are actively progressing around the globe. Every stage of the development of the LHR initiatives had presented peculiar challenges. The best lessons in life are those of someone else's experiences. This paper presents an overview of the development approaches undertaken by four East Asian countries in implementing a national Electronic Health Record (EHR) in the public health system. The major challenges elicited from the review including integration efforts, process reengineering, funding, people, and law and regulation will be presented, compared, discussed and used as lessons learned for the further development of the Malaysian integrated LHR.

Achievement goal profiles and developments in effort and achievement in upper elementary school.

PubMed

Hornstra, Lisette; Majoor, Marieke; Peetsma, Thea

2017-12-01

The multiple goal perspective posits that certain combinations of achievement goals are more favourable than others in terms of educational outcomes. This study aimed to examine longitudinally whether students' achievement goal profiles and transitions between profiles are associated with developments in self-reported and teacher-rated effort and academic achievement in upper elementary school. Participants were 722 fifth-grade students and their teachers in fifth and sixth grade (N = 68). Students reported on their achievement goals and effort in language and mathematics three times in grade 5 to grade 6. Teachers rated students' general school effort. Achievement scores were obtained from school records. Goal profiles were derived with latent profile and transition analyses. Longitudinal multilevel analyses were conducted. Theoretically favourable goal profiles (high mastery and performance-approach goals, low on performance-avoidance goals), as well as transitions from less to more theoretically favourable goal profiles, were associated with higher levels and more growth in effort for language and mathematics and with stronger language achievement gains. Overall, these results provide support for the multiple goal perspective and show the sustained benefits of favourable goal profiles beyond effects of cognitive ability and background characteristics. © 2017 The Authors. British Journal of Education Psychology published by John Wiley & Sons Ltd on behalf of British Psychological Society.

Knowledge, expertise and enthusiasm. Governments need the collaboration of the private sector including NGOs in effectively and timely tackling the global issues.

PubMed

Taniguchi, H

1998-01-01

This article describes the US and Japan's "Common Agenda for Cooperation in Global Perspective." This agenda was launched in July 1993. The aim was to use a bilateral partnership to address critical global challenges in 1) Promotion of Health and Human Development; 2) Protection of the Environment; 3) Responses to Challenges to Global Stability; and 4) Advancement of Science and Technology. The bilateral effort has resulted in 18 initiatives worldwide. Six major accomplishments have occurred in coping with natural disasters in Kobe, Japan, and Los Angeles, US; coral reefs; assistance for women in developing countries; AIDS, children's health; and population problems. The bilateral effort has been successful due to the active involvement of the private sector, including businesses and nongovernmental organizations (NGOs). Many initiatives are developed and implemented in cooperation with local NGOs. The government needs the private sector's technical and managerial fields of expertise. Early investment in NGO efforts ensures the development of self-sustaining programs and public support. An Open Forum was held in March 12-13, 1998, as a commemoration of the 5-year cooperative bilateral effort. Over 300 people attended the Forum. Plenary sessions were devoted to the partnership between public and private sectors under the US-Japan Agenda. Working sessions focused on health and conservation. Participants suggested improved legal systems and social structures for facilitating activities of NGOs, further development by NGOs of their capacities, and support to NGOs from corporations.

Can nurse practitioners and physicians beat parochialism into plowshares?

PubMed

Phillips, Robert L; Harper, Doreen C; Wakefield, Mary; Green, Larry A; Fryer, George E

2002-01-01

Nurse practitioners have evolved into a large and flexible workforce. Far too often, nurse practitioner and physician professional organizations do not work together but rather expend considerable effort jousting in policy arenas. Turf battles interfere with joint advocacy for needed health system change and delay development of interdisciplinary teams that could help patients. A combined, consistent effort is urgently needed for studying, training, and deploying a collaborative, integrated workforce aimed at improving the health care system of tomorrow. The country can ill afford doctors and nurses who ignore one another's capabilities and fail to maximize each other's contributions cost-effectively.

Teachers' Dilemmatic Decision-Making: Reconciling Coexisting Policies of Increased Student Retention and Performance

ERIC Educational Resources Information Center

Jonasson, Charlotte; Mäkitalo, Åsa; Nielsen, Klaus

2015-01-01

In recent years, many countries within the Organisation for Economic Co-operation and Development have formulated educational policies aimed at providing better education to more students. However, this may be perceived as constituting dilemmatic spaces, where teachers must make efforts to reconcile coexisting political demands in their everyday…

Analysing Teachers' Operations When Teaching Students: What Constitutes Scientific Theories?

ERIC Educational Resources Information Center

Holmqvist, Mona O.; Olander, Clas

2017-01-01

The aim of the study is to analyse teachers' efforts to develop secondary school students' knowledge and argumentation skills of what constitutes scientific theories. The analysis is based on Leontiev's three-level structure of activity (activity, action, and operation), as these levels correspond to the questions why, what, and how content is…

Measuring Personal Networks and Their Relationship with Scientific Production

ERIC Educational Resources Information Center

Villanueva-Felez, Africa; Molas-Gallart, Jordi; Escribá-Esteve, Alejandro

2013-01-01

The analysis of social networks has remained a crucial and yet understudied aspect of the efforts to measure Triple Helix linkages. The Triple Helix model aims to explain, among other aspects of knowledge-based societies, "the current research system in its social context" (Etzkowitz and Leydesdorff 2000:109). This paper develops a novel…

Turbocharged Diesels

NASA Technical Reports Server (NTRS)

1984-01-01

In a number of feasibility studies of turbine rotor designs, engineers of Cummins Engine Company, Inc.'s turbocharger group have utilized a computer program from COSMIC. Part of Cummins research effort is aimed toward introduction of advanced turbocharged engines that deliver extra power with greater fuel efficiency. Company claims use of COSMIC program substantially reduced software development costs.

Science and Me: A Student-Driven Science Outreach Program for Lay Adult Audiences

ERIC Educational Resources Information Center

Alexander, Hannah; Waldron, Anna M.; Abell, Sandra K.

2011-01-01

The increasing need for communicating science to the public suggests that future scientists and science educators should be educated in science outreach and trained to communicate with lay audiences. We present a recently developed novel graduate course, which trains students in outreach efforts aimed to increase the public's understanding of…

Manufacturing. Technology Education-Mathematics and Science Interface Project.

ERIC Educational Resources Information Center

Smith, Kenneth L., Ed.

The curriculum materials contained in this document were developed through a cooperative effort by educators in the state of Maryland. It was a curriculum project aimed at the meaningful integration of mathematics and science. It is suggested that these materials be used in two significant ways. First, this document can serve as an instructional…

Construction. Technology Education-Mathematics and Science Interface Project.

ERIC Educational Resources Information Center

Maryland State Dept. of Education, Baltimore. Div. of Vocational-Technical Education.

The curriculum materials contained in this document were developed through a cooperative effort by educators in the state of Maryland. It was a curriculum project aimed at the meaningful integration of mathematics and science. It is suggested that these materials be used in two significant ways. First, this document can serve as an instructional…

Status and prospects for the yellow perch genetic improvement program in Milwaukee, Wisconsin

USDA-ARS?s Scientific Manuscript database

In 2004, a broodstock improvement program was initiated with the aim of developing defined geographic strains of yellow perch that have been selected for improved growth. Following a survey of 19 populations ranging from the Mid-West to the Eastern coast of the United States, and subsequent efforts ...

Access-enabling architectures : new hybrid multi-modal spatial prototypes towards resource and social sustainability : USDOT Region V Regional University Transportation Center final report.

DOT National Transportation Integrated Search

2016-12-19

The efforts of this project aim to capture and engage these potentials through a design-research method that incorporates a top down, data-driven approach with bottom-up stakeholder perspectives to develop prototypical scenario-based design solutions...

Directory of Nature Centers and Related Environmental Education Facilities. Third Revision.

ERIC Educational Resources Information Center

National Audubon Society, New York, NY.

This directory is part of a continuing effort to identify facilities actively involved in environmental education. Designed as a guide for the casual visitor as well as the professional person, it aims to stimulate interest in nature centers, improve communication among facilities, and encourage development of new and better ones. This third…

Asian American Giving to US Higher Education

ERIC Educational Resources Information Center

Tsunoda, Kozue

2010-01-01

Asian Americans have had significant impacts on and within mainstream US society, and their great efforts and gifts in the name of charitable causes are no exception. This study aims to examine perceptions within American university development offices about Asian American giving to US higher education. The article begins with a literature review…

Factors Influencing Students' Adoption of E-Learning: A Structural Equation Modeling Approach

ERIC Educational Resources Information Center

Tarhini, Ali; Masa'deh, Ra'ed; Al-Busaidi, Kamla Ali; Mohammed, Ashraf Bany; Maqableh, Mahmoud

2017-01-01

Purpose: This research aims to examine the factors that may hinder or enable the adoption of e-learning systems by university students. Design/methodology/approach: A conceptual framework was developed through extending the unified theory of acceptance and use of technology (performance expectancy, effort expectancy, hedonic motivation, habit,…

Towards Next Generation Activity-Based Learning Systems

ERIC Educational Resources Information Center

Sampson, Demetrios G.; Karampiperis, Pythagoras

2006-01-01

The need for e-learning systems that support a diverse set of pedagogical requirements has been identified as an important issue in web-based education. Until now, significant research and development effort has been devoted to aiming towards web-based educational systems tailored to specific pedagogical approaches. The most advanced of them are…

Transportation. Technology Education-Mathematics and Science Interface Project.

ERIC Educational Resources Information Center

Smith, Kenneth L., Ed.

The curriculum materials contained in this document were developed through a cooperative effort by educators in the state of Maryland. It was a curriculum project aimed at the meaningful integration of mathematics and science. It is suggested that these materials be used in two significant ways. First, this document can serve as an instructional…

Delivering the Lee Silverman Voice Treatment (LSVT) by Web Camera: A Feasibility Study

ERIC Educational Resources Information Center

Howell, Susan; Tripoliti, Elina; Pring, Tim

2009-01-01

Background: Speech disorders are a feature of Parkinson's disease, typically worsening as the disease progresses. The Lee Silverman Voice Treatment (LSVT) was developed to address these difficulties. It targets vocal loudness as a means of increasing vocal effort and improving coordination across the subsystems of speech. Aims: Currently LSVT is…

The Skills to Pay the Bills: An Evaluation of an Effort to Help Nonprofits Manage Their Finances

ERIC Educational Resources Information Center

Walker, Karen; Grossman, Jean; Andrews, Kristine; Carrington, Nicholas; Rojas, Angela

2015-01-01

This study examines a Wallace Foundation-sponsored initiative aimed at improving the financial management skills and practices of 25 Chicago afterschool providers through training and coaching. Two models for this professional development were provided and each produced long-lasting improvements. Moreover, organizations receiving the…

Patterns of Place-Based Self-Regulation and Associated Mental Health of Urban Adolescents

ERIC Educational Resources Information Center

Mason, Michael J.; Korpela, Kalevi; Mennis, Jeremy; Coatsworth, J. Douglas; Valente, Thomas W.; Pomponio, Amber; Pate, Patricia A.

2010-01-01

Efforts to simultaneously address adolescent self-regulation, activity space (routine locations), and mental health represent a promising social ecological approach aimed at understanding the lives and development of urban youth. This type of examination of contextual influences on self-regulation is considered an important area of developmental…

How to Visit a Museum.

ERIC Educational Resources Information Center

Rebetez, Pierre

The primary aim of this study is to encourage schools and museums to unite their efforts to further the use of the museum for teaching purposes and to promote the full development of creative faculties. The educational function of the museum is explored in consideration of the thirteen to eighteen year old age group. A recurring theme throughout…

Children out of School. Issues.

ERIC Educational Resources Information Center

Department for International Development, London (England).

This paper aims to provide a clear understanding of the circumstances of children who are not in school, as a background for a step-change in national and international efforts to make progress toward the Millennium Development Goals of achieving Universal Primary Education (UPE) by 2015 and the elimination of gender disparities in primary and…

Decentralization of Educational Development Reforms in Nigeria: A Comparative Perspective

ERIC Educational Resources Information Center

Ikoya, Peter O.

2007-01-01

Purpose: The purpose of this paper is to seek to appraise regional compliance to decentralization laws establishing Education Boards and Committees since the Nigerian Government has for some time now been making efforts aimed at reforming her educational system. Design/methodology/approach: Employing ex post facto design, the study uses survey…

An Exploratory Study of Chinese University Undergraduates' Global Competence: Effects of Internationalisation at Home and Motivation

ERIC Educational Resources Information Center

Meng, Qian; Zhu, Chang; Cao, Chun

2017-01-01

Global competence is categorised into three dimensions: knowledge, skills/experience and attitudes. This study aims to investigate the global competence discrepancies of Chinese undergraduates in universities and regions of different development levels, as well as the effects of internationalisation efforts at home and students' motivation on…

Development of a Robotic System for Enhancing Children's Motivation in Constraint Induced Movement Therapy (CIMT).

PubMed

Psychouli, Pavlina; Cheng, Pericles; Dimopoulos, Christos

2017-01-01

This paper presents a novel robotic system, which aims to enhance children's motivation through the gamification of the CIMT process. The system offers adjustability of the required movement skills, ensuring children will put increasingly more effort to achieve the rehabilitation goal, while keeping the task fun and engaging.

A Navy Shore Activity Manpower Planning System for Civilians. Technical Report No. 24.

ERIC Educational Resources Information Center

Niehaus, R. J.; Sholtz, D.

This report describes the U.S. Navy Shore Activity Manpower Planning System (SAMPS) advanced development research project. This effort is aimed at large-scale feasibility tests of manpower models for large Naval installations. These local planning systems are integrated with Navy-wide information systems on a data-communications network accessible…

Developing Teachers' Reasoning about Comparing Distributions: A Cross-Institutional Effort

ERIC Educational Resources Information Center

Tran, Dung; Lee, Hollylynne; Doerr, Helen

2016-01-01

The research reported here uses a pre/post-test model and stimulated recall interviews to assess teachers' statistical reasoning about comparing distributions, when enrolled in a graduate-level statistics education course. We discuss key aspects of the course design aimed at improving teachers' learning and teaching of statistics, and the…

Conducting Qualitative Research on Desertification in Western Lesvos, Greece

ERIC Educational Resources Information Center

Iosifides, Theodoros; Politidis, Theodoros

2005-01-01

The main aim of this article is to present some critical methodological strategies employed in a qualitative research study on local socioeconomic development and desertification in western Lesvos, Greece. Through in-depth qualitative interviews with local producers in western Lesvos, Greece, an effort was made to identify and analyze the links…

Renewables-Friendly Grid Development Strategies. Experience in the United States, Potential Lessons for China

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hurlbut, David; Zhou, Ella; Porter, Kevin

2015-10-01

This report aims to help China's reform effort by providing a concise summary of experience in the United States with "renewables-friendly"" grid management, focusing on experiences that might be applicable to China. It focuses on utility-scale renewables and sets aside issues related to distributed generation.

United Nations Human Space Technology Initiative (HSTI)

NASA Astrophysics Data System (ADS)

Ochiai, Mika; Niu, Aimin; Steffens, Heike; Balogh, Werner; Haubold, Hans; Othman, Mazlan; Doi, Takao

2014-11-01

The Human Space Technology Initiative was launched in 2010 within the framework of the United Nations Programme on Space Applications implemented by the Office for Outer Space Affairs of the United Nations. It aims to involve more countries in activities related to human spaceflight and space exploration and to increase the benefits from the outcome of such activities through international cooperation, to make space exploration a truly international effort. The role of the Initiative in these efforts is to provide a platform to exchange information, foster collaboration between partners from spacefaring and non-spacefaring countries, and encourage emerging and developing countries to take part in space research and benefit from space applications. The Initiative organizes expert meetings and workshops annually to raise awareness of the current status of space exploration activities as well as of the benefits of utilizing human space technology and its applications. The Initiative is also carrying out primary science activities including the Zero-Gravity Instrument Project and the Drop Tower Experiment Series aimed at promoting capacity-building activities in microgravity science and education, particularly in developing countries.

Perception of effort in Exercise Science: Definition, measurement and perspectives.

PubMed

Pageaux, Benjamin

2016-11-01

Perception of effort, also known as perceived exertion or sense of effort, can be described as a cognitive feeling of work associated with voluntary actions. The aim of the present review is to provide an overview of what is perception of effort in Exercise Science. Due to the addition of sensations other than effort in its definition, the neurophysiology of perceived exertion remains poorly understood. As humans have the ability to dissociate effort from other sensations related to physical exercise, the need to use a narrower definition is emphasised. Consequently, a definition and some brief guidelines for its measurement are provided. Finally, an overview of the models present in the literature aiming to explain its neurophysiology, and some perspectives for future research are offered.

Python in Astronomy 2016

NASA Astrophysics Data System (ADS)

Jenness, Tim; Robitaille, Thomas; Tollerud, Erik; Mumford, Stuart; Cruz, Kelle

2016-04-01

The second Python in Astronomy conference will be held from 21-25 March 2016 at the University of Washington eScience Institute in Seattle, WA, USA. Similarly to the 2015 meeting (which was held at the Lorentz Center), we are aiming to bring together researchers, Python developers, users, and educators. The conference will include presentations, tutorials, unconference sessions, and coding sprints. In addition to sharing information about state-of-the art Python Astronomy packages, the workshop will focus on improving interoperability between astronomical Python packages, providing training for new open-source contributors, and developing educational materials for Python in Astronomy. The meeting is therefore not only aimed at current developers, but also users and educators who are interested in being involved in these efforts.

Development of Non-Tracking Solar Thermal Technology

NASA Astrophysics Data System (ADS)

Winston, Roland; Johnston, Bruce; Balkowski, Kevin

2011-11-01

The aims of this research is to develop high temperature solar thermal collectors that do not require complex solar tracking devices to maintain optimal performance. The collector technology developed through these efforts uses non-imaging optics and is referred to as an external compound parabolic concentrator. It is able to operate with a solar thermal efficiency of approximately 50% at a temperature of 200 ° C and can be readily manufactured at a cost between 15 and 18 per square foot.

Clustering excellence to exert transformative change: the Hartford Geriatric Nursing Initiative (HGNI).

PubMed

McBride, Angela Barron; Watman, Rachael; Escobedo, Marcus; Beilenson, John

2011-01-01

This paper describes how the John A. Hartford Foundation sought to maximize the influence of its various geriatric nursing projects by organizing and managing them collectively as the Hartford Geriatric Nursing Initiative (HGNI). This initiative aimed to develop a shared identity, encouraged cross-pollination of efforts, convened project leaders to address opportunities and problems, launched across-project collaborations, and created tools and resources to support overall efforts. This paper ends with some reflections on the processes implemented to maximize HGNI effectiveness, particularly the importance of forging a common identity in order to encourage expanded solutions. The HGNI can serve as an example of how intersecting interests can fuel new ideas, thus helping others think more strategically about change efforts in the future. Copyright © 2011 Elsevier Inc. All rights reserved.

Developing U.S. oversight strategies for nanobiotechnology: learning from past oversight experiences.

PubMed

Paradise, Jordan; Wolf, Susan M; Kuzma, Jennifer; Kuzhabekova, Aliya; Tisdale, Alison W; Kokkoli, Efrosini; Ramachandran, Gurumurthy

2009-01-01

The emergence of nanotechnology, and specifically nanobiotechnology, raises major oversight challenges. In the United States, government, industry, and researchers are debating what oversight approaches are most appropriate. Among the federal agencies already embroiled in discussion of oversight approaches are the Food and Drug Administration (FDA), Environmental Protection Agency (EPA), Department of Agriculture (USDA), Occupational Safety and Health Administration (OSHA), and National Institutes of Health (NIH). All can learn from assessment of the successes and failures of past oversight efforts aimed at emerging technologies. This article reports on work funded by the National Science Foundation (NSF) aimed at learning the lessons of past oversight efforts. The article offers insights that emerge from comparing five oversight case studies that examine oversight of genetically engineered organisms (GEOs) in the food supply, pharmaceuticals, medical devices, chemicals in the workplace, and gene therapy. Using quantitative and qualitative analysis, the authors present a new way of evaluating oversight.

Developing a Multiple Caregiver Group for Caregivers of Adolescents With Disruptive Behaviors.

PubMed

Oruche, Ukamaka M; Robb, Sheri L; Aalsma, Matt; Pescosolido, Bernice; Brown-Podgorski, Brittany; Draucker, Claire Burke

2017-12-01

This article describes the development of a 6-week multiple caregiver group intervention for primary caregivers of adolescents diagnosed with Oppositional Defiant Disorder or Conduct Disorder in low-income African American families. The intervention is aimed at increasing the primary caregivers' self-efficacy in managing interactions within the family and especially with child serving educational, mental health, juvenile justice, and child welfare systems. Development of the intervention involved seven iterative activities performed in a collaborative effort between an interdisciplinary academic team, community engagement specialists, members of the targeted population, and clinical partners from a large public mental health system. The intervention development process described in this article can provide guidance for teams that aim to develop new mental health interventions that target specific outcomes in populations with unique needs. Copyright © 2017 Elsevier Inc. All rights reserved.

Adapting a large database of point of care summarized guidelines: a process description.

PubMed

Delvaux, Nicolas; Van de Velde, Stijn; Aertgeerts, Bert; Goossens, Martine; Fauquert, Benjamin; Kunnamo, Ilka; Van Royen, Paul

2017-02-01

Questions posed at the point of care (POC) can be answered using POC summarized guidelines. To implement a national POC information resource, we subscribed to a large database of POC summarized guidelines to complement locally available guidelines. Our challenge was in developing a sustainable strategy for adapting almost 1000 summarized guidelines. The aim of this paper was to describe our process for adapting a database of POC summarized guidelines. An adaptation process based on the ADAPTE framework was tailored to be used by a heterogeneous group of participants. Guidelines were assessed on content and on applicability to the Belgian context. To improve efficiency, we chose to first aim our efforts towards those guidelines most important to primary care doctors. Over a period of 3 years, we screened about 80% of 1000 international summarized guidelines. For those guidelines identified as most important for primary care doctors, we noted that in about half of the cases, remarks were made concerning content. On the other hand, at least two-thirds of all screened guidelines required no changes when evaluating their local usability. Adapting a large body of POC summarized guidelines using a formal adaptation process is possible, even when faced with limited resources. This can be done by creating an efficient and collaborative effort and ensuring user-friendly procedures. Our experiences show that even though in most cases guidelines can be adopted without adaptations, careful review of guidelines developed in a different context remains necessary. Streamlining international efforts in adapting international POC information resources and adopting similar adaptation processes may lessen duplication efforts and prove more cost-effective. © 2015 The Authors. Journal of Evaluation in Clinical Practice published by John Wiley & Sons, Ltd.

Marginalised social groups in contemporary weee management within social enterprises investments: A study in Greece.

PubMed

Papaoikonomou, K; Kipouros, S; Kungolos, A; Somakos, L; Aravossis, K; Antonopoulos, I; Karagiannidis, A

2009-05-01

This paper deals with the creation of appropriate conditions aimed at developing social services for reuse and recycling of waste electrical and electronic equipment (WEEE), by the inclusion of handicapped and Roma people in the workforce. Application areas for the project are the Hellenic (Greek) regions of Thessaly and North Aegean, where these groups suffer from professional and social exclusion. The efforts to reduce unemployment in the two aforementioned groups, together with the efforts to implement related Greek and European legislation for sustainable WEEE management, are examined here. Furthermore, networking and cooperation at local, regional and central levels between small enterprises, entrepreneurships and local authorities are examined, so that these social enterprises and their corresponding investments may support the development of the Greek alternative WEEE recycling system.

An Update on Design Tools for Optimization of CMC 3D Fiber Architectures

NASA Technical Reports Server (NTRS)

Lang, J.; DiCarlo, J.

2012-01-01

Objective: Describe and up-date progress for NASA's efforts to develop 3D architectural design tools for CMC in general and for SIC/SiC composites in particular. Describe past and current sequential work efforts aimed at: Understanding key fiber and tow physical characteristics in conventional 2D and 3D woven architectures as revealed by microstructures in the literature. Developing an Excel program for down-selecting and predicting key geometric properties and resulting key fiber-controlled properties for various conventional 3D architectures. Developing a software tool for accurately visualizing all the key geometric details of conventional 3D architectures. Validating tools by visualizing and predicting the Internal geometry and key mechanical properties of a NASA SIC/SIC panel with a 3D orthogonal architecture. Applying the predictive and visualization tools toward advanced 3D orthogonal SiC/SIC composites, and combining them into a user-friendly software program.

Soft computing techniques toward modeling the water supplies of Cyprus.

PubMed

Iliadis, L; Maris, F; Tachos, S

2011-10-01

This research effort aims in the application of soft computing techniques toward water resources management. More specifically, the target is the development of reliable soft computing models capable of estimating the water supply for the case of "Germasogeia" mountainous watersheds in Cyprus. Initially, ε-Regression Support Vector Machines (ε-RSVM) and fuzzy weighted ε-RSVMR models have been developed that accept five input parameters. At the same time, reliable artificial neural networks have been developed to perform the same job. The 5-fold cross validation approach has been employed in order to eliminate bad local behaviors and to produce a more representative training data set. Thus, the fuzzy weighted Support Vector Regression (SVR) combined with the fuzzy partition has been employed in an effort to enhance the quality of the results. Several rational and reliable models have been produced that can enhance the efficiency of water policy designers. Copyright © 2011 Elsevier Ltd. All rights reserved.

Processing of Lunar Soil Simulant for Space Exploration Applications

NASA Technical Reports Server (NTRS)

Sen, Subhayu; Ray, Chandra S.; Reddy, Ramana

2005-01-01

NASA's long-term vision for space exploration includes developing human habitats and conducting scientific investigations on planetary bodies, especially on Moon and Mars. To reduce the level of up-mass processing and utilization of planetary in-situ resources is recognized as an important element of this vision. Within this scope and context, we have undertaken a general effort aimed primarily at extracting and refining metals, developing glass, glass-ceramic, or traditional ceramic type materials using lunar soil simulants. In this paper we will present preliminary results on our effort on carbothermal reduction of oxides for elemental extraction and zone refining for obtaining high purity metals. In additions we will demonstrate the possibility of developing glasses from lunar soil simulant for fixing nuclear waste from potential nuclear power generators on planetary bodies. Compositional analysis, x-ray diffraction patterns and differential thermal analysis of processed samples will be presented.

Quality management as knowledge sharing: experiences of the Napa County Health and Human Services Agency.

PubMed

Harrison, Lindsay

2012-01-01

Lacking a coordinated effort in utilizing data and tracking program outcomes, one agency developed a Quality Management (QM) division to facilitate and manage more effective data use. To support this process, the agency sought to develop a collective, agency-wide understanding and investment in improving and measuring client outcomes. Similarly, the agency also focused efforts on creating a culture of transparency and accountability, with goals of improving service, increasing agency integrity, meeting regulatory compliance, and engaging in effective risk management. Operationalizing the QM initiative involved developing procedures, systems, and guidelines that would facilitate the generation of reliable and accurate data that could be used to inform program change and decision-making. This case study describes this agency's experience in successfully creating and implementing a QM initiative aimed at engaging in greater knowledge sharing. Copyright © Taylor & Francis Group, LLC

Analysis Methods for Progressive Damage of Composite Structures

NASA Technical Reports Server (NTRS)

Rose, Cheryl A.; Davila, Carlos G.; Leone, Frank A.

2013-01-01

This document provides an overview of recent accomplishments and lessons learned in the development of general progressive damage analysis methods for predicting the residual strength and life of composite structures. These developments are described within their State-of-the-Art (SoA) context and the associated technology barriers. The emphasis of the authors is on developing these analysis tools for application at the structural level. Hence, modeling of damage progression is undertaken at the mesoscale, where the plies of a laminate are represented as a homogenous orthotropic continuum. The aim of the present effort is establish the ranges of validity of available models, to identify technology barriers, and to establish the foundations of the future investigation efforts. Such are the necessary steps towards accurate and robust simulations that can replace some of the expensive and time-consuming "building block" tests that are currently required for the design and certification of aerospace structures.

Students' responses to authentic assessment designed to develop commitment to performing at their best

NASA Astrophysics Data System (ADS)

Guzzomi, Andrew L.; Male, Sally A.; Miller, Karol

2017-05-01

Engineering educators should motivate and support students in developing not only technical competence but also professional competence including commitment to excellence. We developed an authentic assessment to improve students' understanding of the importance of 'perfection' in engineering - whereby 50% good enough will not be acceptable in industry. Subsequently we aimed to motivate them to practise performing at their best when they practice engineering. Students in a third-year mechanical and mechatronic engineering unit completed a team design project designed with authentic assessment features to replicate industry expectations and a novel marking scheme to encourage the pursuit of excellence. We report mixed responses from students. Students' ratings of their levels of effort on this assessment indicate that many perceived a positive influence on their effort. However, students' comments included several that were consistent with students experiencing the assessment as alienating.

Feedback, Goal Setting, and Incentives Effects on Organizational Productivity.

ERIC Educational Resources Information Center

Pritchard, Robert D.; And Others

This technical paper is one of three produced by a large-scale effort aimed at implementing a new approach to measuring productivity, and using that approach to assess the impact of feedback, goal setting, and incentives on productivity. The productivity measurement system was developed for five units in the maintenance and supply areas at an Air…

Aiming to Meet Workforce Needs: An Evaluation of the Economic and Workforce Development Program

ERIC Educational Resources Information Center

Jez, Su Jin; Adan, Sara

2016-01-01

California's dynamic economy depends on having a large and skilled workforce; consequently, the state must continually support and refine efforts to provide workers with employer-valued competencies. Given the wide range of regional and state needs across this vast state, ensuring that the workforce has the training to keep up with labor market…

The Economics of Reduced Impact Logging in the American Tropics: A Review of Recent Initiatives

Treesearch

Frederick Boltz; Thomas P. Holmes; Douglas R. Carter

1999-01-01

Programs aimed at developing and implementing reduced-impact logging (RIL) techniques are currently underway in important forest regions of Latin America, given the importance of timber production in the American tropics to national and global markets. RIL efforts focus upon planning and extraction methods which lessen harvest impact on residual commercial timber...

Teachers' Professional Agency and Learning--From Adaption to Active Modification in the Teacher Community

ERIC Educational Resources Information Center

Pyhältö, Kirsi; Pietarinen, Janne; Soini, Tiina

2015-01-01

The aim of this study was to examine teacher learning in terms of teachers' professional agency in the professional community of the school. Altogether 2310 Finnish comprehensive school teachers completed a survey. Results showed that teachers' active efforts to learn in the professional community and to promote school development cannot be…

Life in a Democratic Society: A Primary School Civics Course for Poland.

ERIC Educational Resources Information Center

Brzakalik, Krystayna; And Others

This document summarizes a civics course for primary schools in Poland, grades 6-8. The curriculum was developed as part of the Education for Democratic Citizenship in Poland Project, a cooperative effort of the Polish Ministry of National Education and the Mershon Center, The Ohio State University (United States). The project aims to help schools…

An environmental DNA assay for detecting Arctic grayling in the upper Missouri River basin, North America

Treesearch

K. J. Carim; J. C. S. Dysthe; Michael Young; Kevin McKelvey; Michael Schwartz

2016-01-01

The upper Missouri River basin in the northwestern US contains disjunct Arctic grayling (Thymallus arcticus) populations of conservation concern. To assist efforts aimed at understanding Artic grayling distribution, we developed a quantitative PCR assay to detect the presence of Arctic grayling DNA in environmental samples. The assay amplified low...

Power and Energy. Technology Education-Mathematics and Science Interface Project.

ERIC Educational Resources Information Center

Maryland State Dept. of Education, Baltimore. Div. of Vocational-Technical Education.

The curriculum materials contained in this document were developed through a cooperative effort by educators in the state of Maryland. It was a curriculum project aimed at the meaningful integration of mathematics and science. It is suggested that these materials be used in two significant ways. First, this document can serve as an instructional…

Community and School Practices to Reduce Delinquent Behavior: Intervening on the School-to-Prison Pipeline

ERIC Educational Resources Information Center

Shippen, Margaret E.; Patterson, DaShaunda; Green, Kemeche L.; Smitherman, Tracy

2012-01-01

Youth at risk for school failure need community and school supports to reduce the likelihood of developing delinquent behavior. This article provides an overview of community and school approaches aimed at intervening on the school-to-prison pipeline. Community and school efforts are emerging that take into account empirical evidence demonstrating…

Sustainable Design Re-Examined: Integrated Approach to Knowledge Creation for Sustainable Interior Design

ERIC Educational Resources Information Center

Lee, Young S.

2014-01-01

The article focuses on a systematic approach to the instructional framework to incorporate three aspects of sustainable design. It also aims to provide an instruction model for sustainable design stressing a collective effort to advance knowledge creation as a community. It develops a framework conjoining the concept of integrated process in…

Yes, You Can!: A Critical Questions Approach for Developing and Incorporating Intercultural Sensitivity Efforts into ANY Classroom

ERIC Educational Resources Information Center

Osborne, Randall

2016-01-01

The educational literature has blossomed with information on becoming interculturally sensitive (e.g., Bennett, 2004, 2009), discussions on theory and practice for education aimed at enhancing intercultural sensitivity in students (e.g., Bleszynska, 2008), or how to identify and assess intercultural sensitivity as a learning outcome (e.g.,…

Gateway to the Pacific: The Columbia River. Teacher's Resource Book, Grades 5-7.

ERIC Educational Resources Information Center

Osis, Vicki; And Others

Developed as part of an international curriculum effort, this unit aims to provide information to students about the interdependence of Pacific nations and the importance of the Columbia River and its ports in international trade. Geared for grades 5-7, the materials focus on harbors both as natural ecosystems and as locations of international…

Recycling Resources. [Student Handbook, Sound Filmstrips, 12-Inch Record, Pollution Simulation Game, Teacher's Manual

ERIC Educational Resources Information Center

Hatch, C. Richard

A 15- to 20-hour course on materials recycling, teaching junior high school students about environmental problems and solutions, is developed in this set of materials. It attempts to stimulate them to participate in community efforts aimed at improving the environment. Items in the kit include: (1) teacher's manual, with lesson plans enumerating…

An environmental DNA marker for detecting nonnative brown trout (Salmo trutta)

Treesearch

K. J. Carim; T. M. Wilcox; M. Anderson; D. Lawrence; Michael Young; Kevin McKelvey; Michael Schwartz

2016-01-01

Brown trout (Salmo trutta) are widely introduced in western North America where their presence has led to declines of several native species. To assist conservation efforts aimed at early detection and eradication of this species, we developed a quantitative PCR marker to detect the presence of brown trout DNA in environmental samples. The marker strongly...

Cooperative Efforts in Urban Literacy: Learnings from the Urban Literacy Network's Grant Projects.

ERIC Educational Resources Information Center

Williams, Martha

One of the major activities of the Urban Literacy Network (ULN) is a grants program aimed at supporting cooperative, collaborative approaches to developing resources and support systems for literacy in urban areas. Eleven grants were awarded in 1987-1988 in the following urban areas: Boston; Chicago; Denver; El Paso; Houston; Nashville; Oklahoma…

Protecting the Environment for the Sake of Our Common Future. Special Report 4.

ERIC Educational Resources Information Center

Born, Sigrid, Ed.

In June 1992, representatives of more than 170 countries met in Rio de Janeiro, at the United Nations Conference on Environment and Development, to consider international cooperation aimed at preserving the sources of human life. This report presents Germany's involvement in that cooperative effort. The report is presented in six sections: (1) an…

Development of a Model for Minority Recruitment at the United States Naval Academy.

ERIC Educational Resources Information Center

Corpin, Owen D.

The study proposes a recruiting model, which is a coordinated and integrated recruiting effort employing the professional aid of the National Urban League and an expanded minority recruiting staff at the Naval Academy. The model aims to promote interest in the Academy's professional naval education among the black urban community. It is hoped this…

Science Teachers' Utilisation of Innovative Strategies for Teaching Senior School Science in Ilorin, Nigeria

ERIC Educational Resources Information Center

Oyelekan, Oloyede Solomon; Igbokwe, Emoyoke Faith; Olorundare, Adekunle Solomon

2017-01-01

Efforts have been made to improve science teaching in secondary schools in Nigeria, yet, students continue to perform poorly in science subjects. Many innovative teaching strategies have been developed by educators and found to impact significantly on students' academic performance when utilised. Hence, this study was aimed at examining science…

Past Intestinal Parasites.

PubMed

Le Bailly, Matthieu; Araújo, Adauto

2016-08-01

This chapter aims to provide some key points for researchers interested in the study of ancient gastrointestinal parasites. These few pages are dedicated to my colleague and friend, Prof. Adauto Araújo (1951-2015), who participated in the writing of this chapter. His huge efforts in paleoparasitology contributed to the development and promotion of the discipline during more than 30 years.

Next-generation sequencing: hype and hope for development of personalized radiation therapy?

PubMed

Tinhofer, Ingeborg; Niehr, Franziska; Konschak, Robert; Liebs, Sandra; Munz, Matthias; Stenzinger, Albrecht; Weichert, Wilko; Keilholz, Ulrich; Budach, Volker

2015-08-28

The introduction of next-generation sequencing (NGS) in the field of cancer research has boosted worldwide efforts of genome-wide personalized oncology aiming at identifying predictive biomarkers and novel actionable targets. Despite considerable progress in understanding the molecular biology of distinct cancer entities by the use of this revolutionary technology and despite contemporaneous innovations in drug development, translation of NGS findings into improved concepts for cancer treatment remains a challenge. The aim of this article is to describe shortly the NGS platforms for DNA sequencing and in more detail key achievements and unresolved hurdles. A special focus will be given on potential clinical applications of this innovative technique in the field of radiation oncology.

Integration of the enterprise electronic health record and anesthesia information management systems.

PubMed

Springman, Scott R

2011-09-01

Fewer than 5% of anesthesia departments use an electronic medical record (EMR) that is anesthesia specific. Many anesthesia information management systems (AIMS) have been developed with a focus only on the unique needs of anesthesia providers, without being fully integrated into other electronic health record components of the entire enterprise medical system. To understand why anesthesia providers should embrace health information technology (HIT) on a health system-wide basis, this article reviews recent HIT history and reviews HIT concepts. The author explores current developments in efforts to expand enterprise HIT, and the pros and cons of full enterprise integration with an AIMS. Copyright © 2011 Elsevier Inc. All rights reserved.

Parallelizing a peanut butter sandwich

NASA Astrophysics Data System (ADS)

Quenette, S. M.

2005-12-01

This poster aims to demonstrate, in a novel way, why contemporary computational code development is seemingly hard to a geodynamics modeler (i.e. a non-computer-scientist). For example, to utilise comtemporary computer hardware, parallelisation is required. But why do we chose the explicit approach (MPI) over an implicit (OpenMP) one? How does this relate to the typical geodynamics codes. And do we face this same style of problems in every day life? We aim to demonstrate that the little bit of complexity, fore-thought and effort is worth its while.

Evolution of State Outreach Efforts Under SCHIP

PubMed Central

Williams, Susan R.; Rosenbach, Margo L.

2007-01-01

States have shown creativity and adaptability in developing outreach strategies to promote State Children's Health Insurance Program (SCHIP) enrollment. As the program has matured and the fiscal environment has tightened, States have learned what efforts are successful and have tailored their approaches accordingly This article reviews the evolution of State outreach strategies under SCHIP, using qualitative information from all 50 States and the District of Columbia. Early campaigns were aimed at building broad awareness of SCHIP. Over time, States have adapted their outreach campaigns to close the gaps in enrolling hard-to-reach populations, by modifying their target populations, messages, methods, organizational strategies, and emphasis. PMID:17722754

Improving a data-acquisition software system with abstract data type components

NASA Technical Reports Server (NTRS)

Howard, S. D.

1990-01-01

Abstract data types and object-oriented design are active research areas in computer science and software engineering. Much of the interest is aimed at new software development. Abstract data type packages developed for a discontinued software project were used to improve a real-time data-acquisition system under maintenance. The result saved effort and contributed to a significant improvement in the performance, maintainability, and reliability of the Goldstone Solar System Radar Data Acquisition System.

Development of Advanced Technologies for Complete Genomic and Proteomic Characterization of Quantized Human Tumor Cells

DTIC Science & Technology

2013-07-01

AVAILABILITY STATEMENT Approved for Public Release; Distribution Unlimited 13. SUPPLEMENTARY NOTES 14. ABSTRACT With the establishment of GBM cell lines...and quantized cell populations form these GBM patients tumor samples we are able to complete some of our aims of our project. We will continue to...collect tumor samples with consent from families of GBM patients in preparation to perform the molecular analysis of these. Our efforts in the development

Prioritization Methodology for Chemical Replacement

NASA Technical Reports Server (NTRS)

Cruit, W.; Schutzenhofer, S.; Goldberg, B.; Everhart, K.

1993-01-01

This project serves to define an appropriate methodology for effective prioritization of efforts required to develop replacement technologies mandated by imposed and forecast legislation. The methodology used is a semiquantitative approach derived from quality function deployment techniques (QFD Matrix). This methodology aims to weigh the full environmental, cost, safety, reliability, and programmatic implications of replacement technology development to allow appropriate identification of viable candidates and programmatic alternatives. The results are being implemented as a guideline for consideration for current NASA propulsion systems.

Combining traditional dietary assessment methods with novel metabolomics techniques: present efforts by the Food Biomarker Alliance.

PubMed

Brouwer-Brolsma, Elske M; Brennan, Lorraine; Drevon, Christian A; van Kranen, Henk; Manach, Claudine; Dragsted, Lars Ove; Roche, Helen M; Andres-Lacueva, Cristina; Bakker, Stephan J L; Bouwman, Jildau; Capozzi, Francesco; De Saeger, Sarah; Gundersen, Thomas E; Kolehmainen, Marjukka; Kulling, Sabine E; Landberg, Rikard; Linseisen, Jakob; Mattivi, Fulvio; Mensink, Ronald P; Scaccini, Cristina; Skurk, Thomas; Tetens, Inge; Vergeres, Guy; Wishart, David S; Scalbert, Augustin; Feskens, Edith J M

2017-11-01

FFQ, food diaries and 24 h recall methods represent the most commonly used dietary assessment tools in human studies on nutrition and health, but food intake biomarkers are assumed to provide a more objective reflection of intake. Unfortunately, very few of these biomarkers are sufficiently validated. This review provides an overview of food intake biomarker research and highlights present research efforts of the Joint Programming Initiative 'A Healthy Diet for a Healthy Life' (JPI-HDHL) Food Biomarkers Alliance (FoodBAll). In order to identify novel food intake biomarkers, the focus is on new food metabolomics techniques that allow the quantification of up to thousands of metabolites simultaneously, which may be applied in intervention and observational studies. As biomarkers are often influenced by various other factors than the food under investigation, FoodBAll developed a food intake biomarker quality and validity score aiming to assist the systematic evaluation of novel biomarkers. Moreover, to evaluate the applicability of nutritional biomarkers, studies are presently also focusing on associations between food intake biomarkers and diet-related disease risk. In order to be successful in these metabolomics studies, knowledge about available electronic metabolomics resources is necessary and further developments of these resources are essential. Ultimately, present efforts in this research area aim to advance quality control of traditional dietary assessment methods, advance compliance evaluation in nutritional intervention studies, and increase the significance of observational studies by investigating associations between nutrition and health.

A Policy Guide on Integrated Care (PGIC): Lessons Learned from EU Project INTEGRATE and Beyond

PubMed Central

Devroey, Dirk

2017-01-01

Efforts are underway in many European countries to channel efforts into creating improved integrated health and social care services. But most countries lack a strategic plan that is sustainable over time, and that reflects a comprehensive systems perspective. The Policy Guide on Integrated Care (PGIC) as presented in this paper resulted from experiences with the EU Project INTEGRATE and our own work with healthcare reform for patients with chronic conditions at the national and international level. This project is one of the largest EU funded projects on Integrated Care, conducted over a four-year period (2012–2016) and included partners from nine European countries. Project Integrate aimed to gain insights into the leadership, management and delivery of integrated care to support European care systems to respond to the challenges of ageing populations and the rise of people living with long-term conditions. The objective of this paper is to describe the PGIC as both a tool and a reasoning flow that aims at supporting policy makers at the national and international level with the development and implementation of integrated care. Any Policy Guide on Integrated should build upon three building blocks, being a mission, vision and a strategy that aim at capturing the large amount of factors that directly or indirectly influence the successful development of integrated care. PMID:29588631

A Policy Guide on Integrated Care (PGIC): Lessons Learned from EU Project INTEGRATE and Beyond.

PubMed

Borgermans, Liesbeth; Devroey, Dirk

2017-09-25

Efforts are underway in many European countries to channel efforts into creating improved integrated health and social care services. But most countries lack a strategic plan that is sustainable over time, and that reflects a comprehensive systems perspective. The Policy Guide on Integrated Care (PGIC) as presented in this paper resulted from experiences with the EU Project INTEGRATE and our own work with healthcare reform for patients with chronic conditions at the national and international level. This project is one of the largest EU funded projects on Integrated Care, conducted over a four-year period (2012-2016) and included partners from nine European countries. Project Integrate aimed to gain insights into the leadership, management and delivery of integrated care to support European care systems to respond to the challenges of ageing populations and the rise of people living with long-term conditions. The objective of this paper is to describe the PGIC as both a tool and a reasoning flow that aims at supporting policy makers at the national and international level with the development and implementation of integrated care. Any Policy Guide on Integrated should build upon three building blocks, being a mission, vision and a strategy that aim at capturing the large amount of factors that directly or indirectly influence the successful development of integrated care.

Emergency communication and information issues in terrorist events involving radioactive materials.

PubMed

Becker, Steven M

2004-01-01

With the threat posed by terrorism involving radioactive materials now high on the nation's agenda, local, state, and federal agencies are moving to enhance preparedness and response capabilities. Crucial to these efforts is the development of effective risk communication strategies. This article reports findings from an ongoing study of risk communication issues in nuclear/radiological terrorism situations. It is part of a larger CDC-funded effort that aims to better understand communication challenges associated with weapons of mass destruction terrorism incidents. Presented here are formative research findings from 16 focus groups (n = 163) in which a multi-part, hypothetical radioactive materials terrorism situation was discussed. Twelve of the focus groups were carried out with members of the general public (drawn from a variety of ethnic backgrounds and geographic locations), and four groups were composed of first responders, hospital emergency department personnel, and public health professionals. One aim of the focus groups was to elicit detailed information on people's knowledge, views, perceptions, reactions, and concerns related to a nuclear/radiological terrorism event, and to better understand people's specific information needs and preferred information sources. A second aim was to pretest draft informational materials prepared by CDC and NIOSH. Key findings for the public and professional groups are presented, and the implications of the research for developing messages in radiological/nuclear terrorism situations are explored.

Dynamical Nuclear Magnetic Resonance Imaging of Micron-scale Liquids

NASA Astrophysics Data System (ADS)

Sixta, Aimee; Choate, Alexandra; Maeker, Jake; Bogat, Sophia; Tennant, Daniel; Mozaffari, Shirin; Markert, John

We report our efforts in the development of Nuclear Magnetic Resonance Force Microscopy (NMRFM) for dynamical imaging of liquid media at the micron scale. Our probe contains microfluidic samples sealed in thin-walled (µm) quartz tubes, with a micro-oscillator sensor nearby in vacuum to maintain its high mechanical resonance quality factor. Using 10 µm spherical permalloy magnets at the oscillator tips, a 3D T1-resolved image of spin density can be obtained by reconstruction from our magnetostatics-modelled resonance slices; as part of this effort, we are exploring single-shot T1 measurements for faster dynamical imaging. We aim to further enhance imaging by using a 2 ω technique to eliminate artifact signals during the cyclic inversion of nuclear spins. The ultimate intent of these efforts is to perform magnetic resonance imaging of individual biological cells.

Project Responder: technology needs for local emergency response

NASA Astrophysics Data System (ADS)

Beakley, Guy; Garwin, Thomas; Pollard, Neal A.; Singley, George T., III; Tuohy, Robert V.; Lupo, Jasper

2003-09-01

Since April 2001, the Oklahoma City National Memorial Institute for the Prevention of Terrorism has funded an effort by Hicks &Associates, Inc. and the Terrorism Research Center, Inc., aimed ultimately at improving local, state, and federal emergency responders" capabilities for mitigating the effects of chemical, biological, radiological, nuclear or explosive/ incendiary (CBRNE) terrorism. This effort, titled "Project Responder," began by developing an understanding of how state and local responders view their current capabilities, shortfalls, and needs. This paper discusses some of the results of this first phase of the effort that has resulted in a comprehensive report titled "Emergency Responders" Needs, Goals, and Priorities." This paper addresses two of the capabilities from that report which we believe are of most interest to this conference. There are ten other capabilities discussed in the report, which may also be of interest.

Review of Building Data Frameworks across Countries: Lessons for India

DOE Office of Scientific and Technical Information (OSTI.GOV)

Iyer, Maithili; Stratton, Hannah; Mathew, Sangeeta

The report outlines the initial explorations carried out by LBNL on available examples of energy data collection frameworks for buildings. Specifically, this monograph deals with European experience in the buildings sector, the US experience in the commercial buildings sector, and examples of data collection effort in Singapore and China to capture the Asian experience in the commercial sector. The review also provides a summary of the past efforts in India to collect and use commercial building energy data and its strengths and weaknesses. The overall aim of this activity is to help understand the use cases that drive the granularitymore » of data being collected and the range of methodologies adopted for the data collection effort. This review is a key input and reference for developing a data collection framework for India, and also clarifies general thinking on the institutional structure that may be amenable for data collection effort to match the needs and requirements of commercial building sector in India.« less

Novel Concepts for HIV Vaccine Vector Design.

PubMed

Alayo, Quazim A; Provine, Nicholas M; Penaloza-MacMaster, Pablo

2017-01-01

The unprecedented challenges of developing effective vaccines against intracellular pathogens such as HIV, malaria, and tuberculosis have resulted in more rational approaches to vaccine development. Apart from the recent advances in the design and selection of improved epitopes and adjuvants, there are also ongoing efforts to optimize delivery platforms. Viral vectors are the best-characterized delivery tools because of their intrinsic adjuvant capability, unique cellular tropism, and ability to trigger robust adaptive immune responses. However, a known limitation of viral vectors is preexisting immunity, and ongoing efforts are aimed at developing novel vector platforms with lower seroprevalence. It is also becoming increasingly clear that different vectors, even those derived from phylogenetically similar viruses, can elicit substantially distinct immune responses, in terms of quantity, quality, and location, which can ultimately affect immune protection. This review provides a summary of the status of viral vector development for HIV vaccines, with a particular focus on novel viral vectors and the types of adaptive immune responses that they induce.

NASA Work Breakdown Structure (WBS) Handbook

NASA Technical Reports Server (NTRS)

Fleming, Jon F.; Poole, Kenneth W.

2016-01-01

The purpose of this document is to provide program/project teams necessary instruction and guidance in the best practices for Work Breakdown Structure (WBS) and WBS dictionary development and use for project implementation and management control. This handbook can be used for all types of NASA projects and work activities including research, development, construction, test and evaluation, and operations. The products of these work efforts may be hardware, software, data, or service elements (alone or in combination). The aim of this document is to assist project teams in the development of effective work breakdown structures that provide a framework of common reference for all project elements. The WBS and WBS dictionary are effective management processes for planning, organizing, and administering NASA programs and projects. The guidance contained in this document is applicable to both in-house, NASA-led effort and contracted effort. It assists management teams from both entities in fulfilling necessary responsibilities for successful accomplishment of project cost, schedule, and technical goals. Benefits resulting from the use of an effective WBS include, but are not limited to: providing a basis for assigned project responsibilities, providing a basis for project schedule and budget development, simplifying a project by dividing the total work scope into manageable units, and providing a common reference for all project communication.

Work Breakdown Structure (WBS) Handbook

NASA Technical Reports Server (NTRS)

2010-01-01

The purpose of this document is to provide program/project teams necessary instruction and guidance in the best practices for Work Breakdown Structure (WBS) and WBS dictionary development and use for project implementation and management control. This handbook can be used for all types of NASA projects and work activities including research, development, construction, test and evaluation, and operations. The products of these work efforts may be hardware, software, data, or service elements (alone or in combination). The aim of this document is to assist project teams in the development of effective work breakdown structures that provide a framework of common reference for all project elements. The WBS and WBS dictionary are effective management processes for planning, organizing, and administering NASA programs and projects. The guidance contained in this document is applicable to both in-house, NASA-led effort and contracted effort. It assists management teams from both entities in fulfilling necessary responsibilities for successful accomplishment of project cost, schedule, and technical goals. Benefits resulting from the use of an effective WBS include, but are not limited to: providing a basis for assigned project responsibilities, providing a basis for project schedule development, simplifying a project by dividing the total work scope into manageable units, and providing a common reference for all project communication.

Policy Change and the National Essential Medicines List Development Process in Brazil between 2000 and 2014: Has the Essential Medicine Concept been Abandoned?

PubMed

Osorio-de-Castro, Claudia G S; Azeredo, Thiago B; Pepe, Vera L E; Lopes, Luciane C; Yamauti, Sueli; Godman, Brian; Gustafsson, Lars L

2018-04-01

Brazil has had a National Essential Medicines List (EML) since 1964. From 2000 to 2010, five consecutive evidence-based editions were produced, building on the essential medicine concept. In 2012, the government changed course to establish a new paradigm, introducing adoption of new medicines as the main aim within the recommendation process. The objective of the article was to report efforts to develop Brazil's national EML, policy changes from 2000 to 2014, discussing results, challenges and perspectives. Brazilian EML history and development process were collected from legislation, minutes, reports and legal ordinances, from 2000 to 2014. The Brazilian EML and the WHO Model Lists were compared using the Anatomical Therapeutic Chemical system. Overlap between lists was verified, and linear trends were produced. Type of membership, inclusion criteria, procedures, flow and listed medicines varied greatly between the selection committees acting before and after 2012. Paradigm-changing legislation aiming at linking list compliance to public financing in 2012 produced (i) greater importance given to political and administrative stakeholders, (ii) increasing trends in number of medicines over the years, (iii) decrease in use of WHO Model List as a reference and (iv) substitution of an essential medicines list review and update process by an adoption decision output. Other issues remained unchanged. Insufficient efforts for list implementation, such as lack of physician education, presented consequences to the health system. Substantial efforts were made to produce and update the list from 2000 to 2014. However, continuous and intense health litigation disproves process outcome effectiveness. © 2017 Nordic Association for the Publication of BCPT (former Nordic Pharmacological Society).

Vids: Version 2.0 Alpha Visualization Engine

DTIC Science & Technology

2018-04-25

fidelity than existing efforts. Vids is a project aimed at producing more dynamic and interactive visualization tools using modern computer game ...move through and interact with the data to improve informational understanding. The Vids software leverages off-the-shelf modern game development...analysis and correlations. Recently, an ARL-pioneered project named Virtual Reality Data Analysis Environment (VRDAE) used VR and a modern game engine

Understanding and Enabling Marketplace Literacy in Subsistence Contexts: The Development of a Consumer and Entrepreneurial Literacy Educational Program in South India

ERIC Educational Resources Information Center

Viswanathan, Madhubalan; Gajendiran, S.; Venkatesan, R.

2008-01-01

To function in the economic realm, two important resources that individuals need are finances and know-how. Whereas there has been considerable attention on microfinancing, we describe an educational program that focuses on enabling generic skills about the marketplace and complements these important efforts. We conducted research aimed at…

Integrated Multidisciplinary Design of High Pressure Multistage Compressor Systems (la Conception integree des compresseurs multi-etage a haute performance)

DTIC Science & Technology

1998-09-01

development ONERA and SNECMA and is described in [Nicoud, 91]. This methodology [ Karadimas , 1997]. The aim of all efforts method solves the Quasi-3D...computer power, 1994 2-11 BERTHILLIER, M., DUPONT, C., MONDAL, R., KARADIMAS , G. : New Ways for the Design the BARRAU, J.J. : Blade Forced Response

Health Education Efforts in Uncertain Times: Helping to Ensure Healthy Pregnancies in a Time of Crisis

ERIC Educational Resources Information Center

Flores, Alina L.; Weber, Mary Kate; Kilker, Katie P.; Dang, Elizabeth P.; Lindsey, Lisa L. Massi

2007-01-01

Hurricane Katrina caused immense upheaval and disrupted many lives. Among those affected were pregnant women. A public service announcement, website content, and a fact sheet were developed to inform pregnant women about the issues that could potentially affect their health and that of their babies. The aim of these products was to provide health…

Specially Made for Science: Researchers Develop Online Tools For Collaborations

ERIC Educational Resources Information Center

Guterman, Lila

2008-01-01

Blogs, wikis, and social-networking sites such as Facebook may get media buzz these days, but for scientists, engineers, and doctors, they are not even on the radar. The most effective tools of the Internet for such people tend to be efforts more narrowly aimed at their needs, such as software that helps geneticists replicate one another's…

Laying the Groundwork for an Interdisciplinary Effort Aimed at Prevention of Pregnancy among Middle School Students. Final Report, from July 1978 to June 1979.

ERIC Educational Resources Information Center

Morse, Betty R.; And Others

This report presents results of a project to provide useful information for planning pregnancy prevention programs. It focuses on five project objectives: (1) identification of factors associated with adolescent sexual behavior, contraceptive behavior, and pregnancy; (2) development of instructional objectives or skills associated with pregnancy…

Latin America Report.

DTIC Science & Technology

1985-08-09

They acknowledged the importance of tourism to promote the economic integra- tion and development of the two countries and stated their intention to...adopt measures aimed at increasing tourism through coordinated and joint efforts by national authorities. This work will be done by a commission to...6 [Article by Anthony Forbes] [Excerpts] FOREIGN and Tourism Minister Clement Maynard said today that the governments of the Bahamas and other

A Recent Swedish Attempt to Weaken State Control and Strengthen School Autonomy: The Experiment with Local Time Schedules

ERIC Educational Resources Information Center

Ronnberg, Linda

2007-01-01

In 1999, after a series of far-reaching reforms aiming at decentralisation, deregulation and increased local autonomy in Swedish education, the Government decided to introduce a five-year experiment, which would develop these reform efforts even further. Even though Swedish compulsory schools already were the most autonomous in Europe with regard…

Validation of a Questionnaire to Measure Mastery Motivation among Chinese Preschool Children

ERIC Educational Resources Information Center

Leung, Cynthia; Lo, S. K.

2013-01-01

The aim of this study was to validate a questionnaire on mastery motivation (task and effort) for use with Chinese preschool children in Hong Kong. A parent version and a teacher version were developed and evaluated. Participants included 457 children (230 boys and 227 girls) aged four and five years old, their preschool teachers and their…

Arbiters of Effectiveness and Efficiency: The Frames and Strategies of Management Consulting Firms in US Higher Education Reform

ERIC Educational Resources Information Center

McClure, Kevin R.

2017-01-01

A growing number of public colleges and universities in the United States have hired management consulting firms to help develop strategies aimed at increasing institutional effectiveness and efficiency. The purpose of this paper is to explore the frames and strategies of consultants in US public higher education reform efforts. Drawing upon a…

Establishing a Formal Cross-Cultural Mentoring Organization and Program: A Case Study of International Student Mentor Association in a Higher Education Context

ERIC Educational Resources Information Center

Kim, Sewon; Egan, Toby

2011-01-01

Purpose: The aim of this paper is to offer potential insight regarding formal cross-cultural mentoring organization and program development in higher education contexts and beyond, by elaborating regarding the founding and programmatic efforts of an International Student Mentor Association (ISMA) at a large university in North America.…

Knowledge to serve the city: insights from an emerging knowledge-action network to address vulnerability and sustainability in San Juan, Puerto Rico

Treesearch

T.A. Munoz-Erickson; A.E. Lugo; E. Melendez-Ackerman; L.E. Santiago-Acevedo; J. Seguinot-Barbosa; P. Mendez-Lazaro

2014-01-01

This paper presents initial efforts to establish the San Juan Urban Long-Term Research Area Exploratory (ULTRA-Ex), a long-term program aimed at developing transdisciplinary social-ecological system (SES) research to address vulnerability and sustainability for the municipality of San Juan. Transdisciplinary approaches involve the collaborations between researchers,...

"They'll Grow up and Be Adults Wanting to Take Care of Our Environment": The Story of Jan and Critical Literacy

ERIC Educational Resources Information Center

Gove, Mary K.; Still, Kristine L.

2014-01-01

Two university professors and 11 urban school faculty collaborated on a professional development (PD) effort focused on critical literacy to explore literacy practices aimed to reshape definitions of literacy that involved questioning power relationships concerning the environment and social justice. We examined the journey of a veteran teacher,…

Relationships between the Family Environment and School-Based Obesity Prevention Efforts: Can School Programs Help Adolescents Who Are Most in Need?

ERIC Educational Resources Information Center

Bauer, K. W.; Neumark-Sztainer, D.; Hannan, P. J.; Fulkerson, J. A.; Story, M.

2011-01-01

Identifying factors that contribute to students' behavior and weight improvements during school-based obesity prevention interventions is critical for the development of effective programs. The current study aims to determine whether the support and resources that adolescent girls received from their families were associated with improvements in…

Toward Inclusive STEM Classrooms: What Personal Role Do Faculty Play?

PubMed Central

Killpack, Tess L.; Melón, Laverne C.

2016-01-01

Private and public policies are increasingly aimed at supporting efforts to broaden participation of a diverse body of students in higher education. Unfortunately, this increase in student diversity does not always occur alongside changes in institutional culture. Unexamined biases in institutional culture can prevent diverse students from thriving and persisting in science, technology, engineering, and mathematics (STEM) fields. Given the daily personal interactions that faculty have with students, we suggest that individual educators have the opportunity, and responsibility, to improve the retention and persistence of diverse students. However, in our experience, faculty professional development programs often limit discussions of diversity to “comfortable” topics (such as learning styles) and miss opportunities to explore deeper issues related to faculty privilege, implicit bias, and cues for stereotype threat that we all bring to the classroom. In this essay, we present a set of social science concepts that we can extend to our STEM courses to inform our efforts at inclusive excellence. We have recommended strategies for meaningful reflection and professional development with respect to diversity and inclusion, and aim to empower faculty to be change agents in their classrooms as a means to broadening participation in STEM fields. PMID:27496362

The Kaiser Permanente Clinician Cultural and Linguistic Assessment Initiative: Research and Development in Patient–Provider Language Concordance

PubMed Central

MSN, Gayle Tang; Lanza, Oscar; Rodriguez, Fátima Marinely; Chang, Annie

2011-01-01

Patient–clinician language concordance is a critical component of the language access equation and is considered the gold standard for communication. As a result of lack of validated testing standards, measures, and tools, Kaiser Permanente developed the Clinician Cultural and Linguistic Assessment Initiative to ensure verifiable linguistic proficiency in clinical encounters and has established a standard level whereby the clinician is deemed to have a qualifying level of proficiency in communicating directly with patients independent of an interpreter. Our benchmarking efforts in language concordance have been rooted with the key aim to identify talented bilingual and bicultural clinician workforce and to establish the systems foundation to coordinate appropriate language services. We share accomplishments, lessons learned, and promising practices to inform future efforts in language concordance. PMID:21228282

Standard Hardware Acquisition and Reliability Program's (SHARP's) efforts in incorporating fiber optic interconnects into standard electronic module (SEM) connectors

NASA Astrophysics Data System (ADS)

Riggs, William R.

1994-05-01

SHARP is a Navy wide logistics technology development effort aimed at reducing the acquisition costs, support costs, and risks of military electronic weapon systems while increasing the performance capability, reliability, maintainability, and readiness of these systems. Lower life cycle costs for electronic hardware are achieved through technology transition, standardization, and reliability enhancement to improve system affordability and availability as well as enhancing fleet modernization. Advanced technology is transferred into the fleet through hardware specifications for weapon system building blocks of standard electronic modules, standard power systems, and standard electronic systems. The product lines are all defined with respect to their size, weight, I/O, environmental performance, and operational performance. This method of defining the standard is very conducive to inserting new technologies into systems using the standard hardware. This is the approach taken thus far in inserting photonic technologies into SHARP hardware. All of the efforts have been related to module packaging; i.e. interconnects, component packaging, and module developments. Fiber optic interconnects are discussed in this paper.

Rational Design and Nanoscale Integration of Multi-Heterostructures as Highly Efficient Photocatalysts

DOE Office of Scientific and Technical Information (OSTI.GOV)

Duan, Xiangfeng

2017-11-03

The central goal of this project is to design and synthesize complex multi-hetero-nanostructures and fundamental investigation of their potential as efficient and robust photocatalysts. Specifically, the project aims to develop a nanoscale light-harvesting antenna that can efficiently convert solar photon energy into excited electrons and holes, and integrate such antenna with efficient redox nanocatalysts that can harness the photo-generated carriers for productive electrochemical processes. Focusing on this central goal, we have investigated several potential light-harvesting antennas including: silicon nanowires, nitrogen-doped TiO2 nanowires and the emerging perovskite materials. We also devoted considerable effort in developing electrocatalysts including: hydrogen evolution reaction (HER)more » catalysts, oxygen evolution reaction (OER) catalysts and oxygen reduction reaction catalysts (ORR). In previous annual reports, we have described our effort in the synthesis and photoelectrochemical properties of silicon, TiO2, perovskite-based materials and heterostructures. Here, we focus our discussion on the recent effort in investigating charge transport dynamics in organolead halide perovskites, as well as carbon nanostructure and platinum nanostructure-based electrocatalysts for energy conversion and storage.« less

RedeAmericas: building research capacity in young leaders for sustainable growth in community mental health services in Latin America.

PubMed

Yang, L; Pratt, C; Valencia, E; Conover, S; Fernández, R; Burrone, M S; Cavalcanti, M T; Lovisi, G; Rojas, G; Alvarado, R; Galea, S; Price, L N; Susser, E

2017-01-01

The purpose of this paper is to describe the development and initial accomplishments of a training program of young leaders in community mental health research as part of a Latin American initiative known as RedeAmericas. RedeAmericas was one of five regional 'Hubs' funded by the National Institute of Mental Health (NIMH) to improve community mental health care and build mental health research capacity in low- and middle-income countries. It included investigators in six Latin American cities - Santiago, Chile; Medellín, Colombia; Rio de Janeiro, Brazil; and Córdoba, Neuquén, and Buenos Aires in Argentina - working together with a team affiliated with the Global Mental Health program at Columbia University in New York City. One component of RedeAmericas was a capacity-building effort that included an Awardee program for early career researchers in the mental health field. We review the aims of this component, how it developed, and what was learned that would be useful for future capacity-building efforts, and also comment on future prospects for maintaining this type of effort.

Data collection for cooperative water resources modeling in the Lower Rio Grande Basin, Fort Quitman to the Gulf of Mexico.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Passell, Howard David; Pallachula, Kiran; Tidwell, Vincent Carroll

2004-10-01

Water resource scarcity around the world is driving the need for the development of simulation models that can assist in water resources management. Transboundary water resources are receiving special attention because of the potential for conflict over scarce shared water resources. The Rio Grande/Rio Bravo along the U.S./Mexican border is an example of a scarce, transboundary water resource over which conflict has already begun. The data collection and modeling effort described in this report aims at developing methods for international collaboration, data collection, data integration and modeling for simulating geographically large and diverse international watersheds, with a special focus onmore » the Rio Grande/Rio Bravo. This report describes the basin, and the data collected. This data collection effort was spatially aggregated across five reaches consisting of Fort Quitman to Presidio, the Rio Conchos, Presidio to Amistad Dam, Amistad Dam to Falcon Dam, and Falcon Dam to the Gulf of Mexico. This report represents a nine-month effort made in FY04, during which time the model was not completed.« less

Prioritization methodology for chemical replacement

NASA Technical Reports Server (NTRS)

Goldberg, Ben; Cruit, Wendy; Schutzenhofer, Scott

1995-01-01

This methodology serves to define a system for effective prioritization of efforts required to develop replacement technologies mandated by imposed and forecast legislation. The methodology used is a semi quantitative approach derived from quality function deployment techniques (QFD Matrix). QFD is a conceptual map that provides a method of transforming customer wants and needs into quantitative engineering terms. This methodology aims to weight the full environmental, cost, safety, reliability, and programmatic implications of replacement technology development to allow appropriate identification of viable candidates and programmatic alternatives.

Development of Lightweight CubeSat with Multi-Functional Structural Battery Systems

NASA Technical Reports Server (NTRS)

Karkkainen, Ryan L.; Hunter, Roger C.; Baker, Christopher

2017-01-01

This collaborative multi-disciplinary effort aims to develop a lightweight, 1-unit (1U) CubeSat (10x10x10 cm) which utilizes improved and fully integrated structural battery materials for mission life extension, larger payload capability, and significantly reduced mass.The electrolytic carbon fiber material serves the multifunctional capacitive energy system as both a lightweight, load bearing structure and an electrochemical battery system. This implementation will improve traditional multifunctional energy storage concepts with a highly effective energy storage capability.

Pleasure: An under-utilised 'P' in social marketing for healthy eating.

PubMed

Pettigrew, Simone

2016-09-01

The escalating obesity crisis has resulted in a wide range of efforts to develop more effective prevention approaches. This review article explores the potential for the concept of food pleasure to take centre stage in social marketing programs that aim to encourage healthy eating. Literature relating to food motivations is reviewed and the various strategic phases involved in developing social marketing programs are outlined in the context of incorporating a food pleasure focus. Copyright © 2015 Elsevier Ltd. All rights reserved.

'Emerging technologies for the changing global market' - Prioritization methodology for chemical replacement

NASA Technical Reports Server (NTRS)

Cruit, Wendy; Schutzenhofer, Scott; Goldberg, Ben; Everhart, Kurt

1993-01-01

This project served to define an appropriate methodology for effective prioritization of technology efforts required to develop replacement technologies mandated by imposed and forecast legislation. The methodology used is a semiquantitative approach derived from quality function deployment techniques (QFD Matrix). This methodology aims to weight the full environmental, cost, safety, reliability, and programmatic implications of replacement technology development to allow appropriate identification of viable candidates and programmatic alternatives. The results will be implemented as a guideline for consideration for current NASA propulsion systems.

Emerging technologies for the changing global market

NASA Technical Reports Server (NTRS)

Cruit, Wendy; Schutzenhofer, Scott; Goldberg, Ben; Everhart, Kurt

1993-01-01

This project served to define an appropriate methodology for effective prioritization of technology efforts required to develop replacement technologies mandated by imposed and forecast legislation. The methodology used is a semi-quantative approach derived from quality function deployment techniques (QFD Matrix). This methodology aims to weight the full environmental, cost, safety, reliability, and programmatic implications of replacement technology development to allow appropriate identification of viable candidates and programmatic alternatives. The results will be implemented as a guideline for consideration for current NASA propulsion systems.

Analytical prediction of digital signal crosstalk of FCC

NASA Technical Reports Server (NTRS)

Belleisle, A. P.

1972-01-01

The results are presented of study effort whose aim was the development of accurate means of analyzing and predicting signal cross-talk in multi-wire digital data cables. A complete analytical model is developed n + 1 wire systems of uniform transmission lines with arbitrary linear boundary conditions. In addition, a minimum set of parameter measurements required for the application of the model are presented. Comparisons between cross-talk predicted by this model and actual measured cross-talk are shown for a six conductor ribbon cable.

Metallic Scaffolds for Bone Regeneration

PubMed Central

Alvarez, Kelly; Nakajima, Hideo

2009-01-01

Bone tissue engineering is an emerging interdisciplinary field in Science, combining expertise in medicine, material science and biomechanics. Hard tissue engineering research is focused mainly in two areas, osteo and dental clinical applications. There is a lot of exciting research being performed worldwide in developing novel scaffolds for tissue engineering. Although, nowadays the majority of the research effort is in the development of scaffolds for non-load bearing applications, primarily using soft natural or synthetic polymers or natural scaffolds for soft tissue engineering; metallic scaffolds aimed for hard tissue engineering have been also the subject of in vitro and in vivo research and industrial development. In this article, descriptions of the different manufacturing technologies available to fabricate metallic scaffolds and a compilation of the reported biocompatibility of the currently developed metallic scaffolds have been performed. Finally, we highlight the positive aspects and the remaining problems that will drive future research in metallic constructs aimed for the reconstruction and repair of bone.

Evaluation of Commercially-Available Equipment for the ...

EPA Pesticide Factsheets

Report The Underground Transport Restoration (UTR) project is an inter-agency effort. This effort aims to improve the capability for transit systems to quickly and efficiently recover from a biological contamination incident by refining existing methods, tools and protocols for characterization, clean-up, and clearance of contamination in physical structures (i.e., tunnels, stations) and rolling stock (i.e., subway trains). The aim was to evaluate existing sampling, characterization, and decontamination technologies through experimentation, table-top exercises and operational demonstrations to develop guidance and decision frameworks and support tools through interactions of local, state and federal partners. In this investigation, a survey of commercially-available or fielded equipment was conducted and resulted in three pieces of identified equipment that could be used or rapidly modified for use in dispensing liquid chemicals to decontaminate surfaces following a biological contamination incident. documenting lab-scale testing, field-scale testing, and an equipment demonstration of commercial equipment used to decontaminate subway infrastructure following a biological incident.

A Research Agenda to Underpin Malaria Eradication

PubMed Central

Alonso, Pedro L.; Brown, Graham; Arevalo-Herrera, Myriam; Binka, Fred; Chitnis, Chetan; Collins, Frank; Doumbo, Ogobara K.; Greenwood, Brian; Hall, B. Fenton; Levine, Myron M.; Mendis, Kamini; Newman, Robert D.; Plowe, Christopher V.; Rodríguez, Mario Henry; Sinden, Robert; Slutsker, Laurence; Tanner, Marcel

2011-01-01

The interruption of malaria transmission worldwide is one of the greatest challenges for international health and development communities. The current expert view suggests that, by aggressively scaling up control with currently available tools and strategies, much greater gains could be achieved against malaria, including elimination from a number of countries and regions; however, even with maximal effort we will fall short of global eradication. The Malaria Eradication Research Agenda (malERA) complements the current research agenda—primarily directed towards reducing morbidity and mortality—with one that aims to identify key knowledge gaps and define the strategies and tools that will result in reducing the basic reproduction rate to less than 1, with the ultimate aim of eradication of the parasite from the human population. Sustained commitment from local communities, civil society, policy leaders, and the scientific community, together with a massive effort to build a strong base of researchers from the endemic areas will be critical factors in the success of this new agenda. PMID:21311579

Global hunger: a challenge to agricultural, food, and nutritional sciences.

PubMed

Wu, Shiuan-Huei; Ho, Chi-Tang; Nah, Sui-Lin; Chau, Chi-Fai

2014-01-01

Hunger has been a concern for generations and has continued to plague hundreds of millions of people around the world. Although many efforts have been devoted to reduce hunger, challenges such as growing competitions for natural resources, emerging climate changes and natural disasters, poverty, illiteracy, and diseases are posing threats to food security and intensifying the hunger crisis. Concerted efforts of scientists to improve agricultural and food productivity, technology, nutrition, and education are imperative to facilitate appropriate strategies for defeating hunger and malnutrition. This paper provides some aspects of world hunger issues and summarizes the efforts and measures aimed to alleviate food problems from the food and nutritional sciences perspectives. The prospects and constraints of some implemented strategies for alleviating hunger and achieving sustainable food security are also discussed. This comprehensive information source could provide insights into the development of a complementary framework for dealing with the global hunger issue.

Providing oceanographic data and information for Pacific Island communities

NASA Astrophysics Data System (ADS)

Potemra, James; Maurer, John; Burns, Echelle

2016-04-01

The Pacific Islands Ocean Observing System (PacIOOS; http://pacioos.org) is a data-serving group that relies on and promotes data interoperability. The PacIOOS "enterprise" is part of a large, US National effort aimed at providing information about the ocean environment to a wide range of users. These users range from casual beach-goers interested in the latest weather forecast or wave conditions to federal agencies responsible for public safety. In an effort to bridge the gap between the scientific community, who are responsible for making measurements and running forecast models, and the wide-ranging end-users, the data management group in PacIOOS has developed the infrastructure to host and distribute ocean-related data. The efficiency of this system has also allowed the group to build web-based tools to further help users. In this presentation we describe these efforts in more detail.

Ion irradiation testing and characterization of FeCrAl candidate alloys

DOE Office of Scientific and Technical Information (OSTI.GOV)

Anderoglu, Osman; Aydogan, Eda; Maloy, Stuart Andrew

2014-10-29

The Fuel Cycle Research and Development program’s Advanced Fuels Campaign has initiated a multifold effort aimed at facilitating development of accident tolerant fuels. This effort involves development of fuel cladding materials that will be resistant to oxidizing environments for extended period of time such as loss of coolant accident. Ferritic FeCrAl alloys are among the promising candidates due to formation of a stable Al₂O₃ oxide scale. In addition to being oxidation resistant, these promising alloys need to be radiation tolerant under LWR conditions (maximum dose of 10-15 dpa at 250 – 350°C). Thus, in addition to a number of commerciallymore » available alloys, nuclear grade FeCrAl alloys developed at ORNL were tested using high energy proton irradiations and subsequent characterization of irradiation hardening and damage microstructure. This report summarizes ion irradiation testing and characterization of three nuclear grade FeCrAl cladding materials developed at ORNL and four commercially available Kanthal series FeCrAl alloys in FY14 toward satisfying FCRD campaign goals.« less

Astronomy for Development: Path to Global Impact

NASA Astrophysics Data System (ADS)

Venugopal, R.; Govender, K.; Grant, E.

2017-07-01

The IAU established its Office of Astronomy for Development in 2011 in Cape Town, South Africa, in partnership with the South African National Research Foundation, and hosted at the South African Astronomical Observatory. The primary purpose of the office has been to implement the IAU's decadal strategic plan which aims to use astronomy to stimulate education and development globally. Since its inception there have been nine regional offices established, including one in the Latin American region which focuses on Andean countries. Following a very positive external review in 2015, as well as a supportive resolution by the 2015 IAU General Assembly to continue the work of the office, the OAD is now in a position to move beyond the setting up of structures to a more intensive effort aimed at measuring and delivering programmes with broader global impact.

Accessing multimedia content from mobile applications using semantic web technologies

NASA Astrophysics Data System (ADS)

Kreutel, Jörn; Gerlach, Andrea; Klekamp, Stefanie; Schulz, Kristin

2014-02-01

We describe the ideas and results of an applied research project that aims at leveraging the expressive power of semantic web technologies as a server-side backend for mobile applications that provide access to location and multimedia data and allow for a rich user experience in mobile scenarios, ranging from city and museum guides to multimedia enhancements of any kind of narrative content, including e-book applications. In particular, we will outline a reusable software architecture for both server-side functionality and native mobile platforms that is aimed at significantly decreasing the effort required for developing particular applications of that kind.

Biomedical Big Data Training Collaborative (BBDTC): An effort to bridge the talent gap in biomedical science and research.

PubMed

Purawat, Shweta; Cowart, Charles; Amaro, Rommie E; Altintas, Ilkay

2017-05-01

The BBDTC (https://biobigdata.ucsd.edu) is a community-oriented platform to encourage high-quality knowledge dissemination with the aim of growing a well-informed biomedical big data community through collaborative efforts on training and education. The BBDTC is an e-learning platform that empowers the biomedical community to develop, launch and share open training materials. It deploys hands-on software training toolboxes through virtualization technologies such as Amazon EC2 and Virtualbox. The BBDTC facilitates migration of courses across other course management platforms. The framework encourages knowledge sharing and content personalization through the playlist functionality that enables unique learning experiences and accelerates information dissemination to a wider community.

Proceedings of the 1988 International Meeting on Reduced Enrichment for Research and Test Reactors

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1993-07-01

The international effort to develop and implement new research reactor fuels utilizing low-enriched uranium, instead of highly- enriched uranium, continues to make solid progress. This effort is the cornerstone of a widely shared policy aimed at reducing, and possibly eliminating, international traffic in highly-enriched uranium and the nuclear weapon proliferation concerns associated with this traffic. To foster direct communication and exchange of ideas among the specialists in this area, the Reduced Enrichment Research and Test Reactor (RERTR) Program, at Argonne National Laboratory, sponsored this meeting as the eleventh of a series which began 1978. Individual papers presented at the meetingmore » have been cataloged separately.« less

Fathers' views on their financial situations, father-child activities, and preventing child injuries.

PubMed

Olsen, Lise L; Oliffe, John L; Brussoni, Mariana; Creighton, Genevieve

2015-01-01

Unintentional injuries are a leading public health problem for children, particularly among those living at lower socioeconomic levels. Parents play an important preventive role, and the aim of this study was to examine fathers' views on the role of their family financial situation in preventing children's injuries. In-depth interviews were conducted with 15 fathers of children 2 to 7 years living in western Canada. Questions solicited fathers' views about their financial situation and their child injury prevention efforts. Data analysis was underpinned by masculinity theory and guided by constant comparative grounded theory methods. Findings included that fathers living with fewer financial limitations emphasized use of safety equipment and aligned themselves with provider and protector masculine ideals. Fathers with moderate financial constraint described more child-centered safety efforts and efforts to manage finances. Those facing greatest constraint demonstrated aspects of marginalized masculinities, whereby they acknowledged their economic provider limitations while strongly aligning with the protector role. These findings hold relevance for development of interventions aimed at reducing child injury risk inequities. Taking into account how masculinities may shape their beliefs and practices can inform design of father-centered interventions for men living at different points on the socioeconomic spectrum. © The Author(s) 2013.

Philosophy in medical education: a means of protecting mental health.

PubMed

Keller, Eric J

2014-08-01

This study sought to identify and examine less commonly discussed challenges to positive mental health faced by medical students, residents, and physicians with hopes of improving current efforts to protect the mental health of these groups. Additionally, this work aimed to suggest an innovative means of preventing poor mental health during medical education. Literature on medical student, resident, and physician mental health was carefully reviewed and a number of psychiatrists who treat physician-patients were interviewed. The culture of medicine, medical training, common physician psychology and identity, and conflicting professional expectations all seem to contribute to poor mental health among medical students, residents, and physicians. Many current efforts may be more successful by better addressing the negative effects of these characteristics of modern medicine. Programs aimed at promoting healthy mental lifestyles during medical education should continue to be developed and supported to mitigate the deleterious effects of the challenging environment of modern medicine. To improve these efforts, educators may consider incorporating philosophical discussions on meaning and fulfillment in life between medical students and faculty. Through medical school faculty members sharing and living out their own healthy outlooks on life, students may emulate these habits and the culture of medicine may become less challenging for positive mental health.

The Majorana Double Beta Decay Experiment:. Present Status

NASA Astrophysics Data System (ADS)

Aguayo, E.; Avignone, F. T.; Back, H. O.; Barabash, A. S.; Beene, J. R.; Bergevin, M.; Bertrand, F. E.; Boswell, M.; Brudanin, V.; Busch, M.; Chan, Y.-D.; Christofferson, C. D.; Collar, J. I.; Combs, D. C.; Cooper, R. J.; Detwiler, J. A.; Doe, P. J.; Efremenko, Yu.; Egorov, V.; Ejiri, H.; Elliott, S. R.; Esterline, J.; Fast, J. E.; Fields, N.; Finnerty, P.; Fraenkle, F. M.; Gehman, V. M.; Giovanetti, G. K.; Green, M. P.; Guiseppe, V. E.; Gusey, K.; Hallin, A. L.; Hazama, R.; Henning, R.; Hime, A.; Hoppe, E. W.; Horton, M.; Howard, S.; Howe, M. A.; Johnson, R. A.; Keeter, K. J.; Keller, C.; Kidd, M. F.; Knecht, A.; Kochetov, O.; Konovalov, S. I.; Kouzes, R. T.; Laferriere, B. D.; Laroque, B. H.; Leon, J.; Leviner, L. E.; Loach, J. C.; Macmullin, S.; Marino, M. G.; Martin, R. D.; Mei, D.-M.; Merriman, J. H.; Miller, M. L.; Mizouni, L.; Nomachi, M.; Orrell, J. L.; Overman, N. R.; Phillips, D. G.; Poon, A. W. P.; Perumpilly, G.; Prior, G.; Radford, D. C.; Rielage, K.; Robertson, R. G. H.; Ronquest, M. C.; Schubert, A. G.; Shima, T.; Shirchenko, M.; Snavely, K. J.; Steele, D.; Strain, J.; Thomas, K.; Timkin, V.; Tornow, W.; Vanyushin, I.; Varner, R. L.; Vetter, K.; Vorren, K.; Wilkerson, J. F.; Yakushev, E.; Young, A. R.; Yu, C.-H.; Yumatov, V. I.; Zhang, C.

2013-11-01

The Majorana collaboration is actively pursuing research and development aimed at a tonne-scale 76Ge neutrinoless double-beta decay (0νββ) experiment. The current, primary focus is the construction of the Majorana Demonstrator experiment, an R&D effort that will field approximately 40 kg of germanium detectors with mixed enrichment levels. This article provides a status update on the construction of the Demonstrator.

Minority Recruiting in The New York City Police Department: Part I. The Attraction of Candidates, Part II. The Retention of Candidates.

ERIC Educational Resources Information Center

Hunt, Isaac C., Jr.; Cohen, Bernard

In an effort to increase the proportion of minority group members on the New York City police force, this study was commissioned: (1) to learn the reasons for present difficulties in minority recruitment, (2) to analyze the effectiveness of current recruiting strategies and programs, and (3) to develop new approaches aimed at improving minority…

A Study of the Views of Information Technologies Teachers Regarding In-Service Training

ERIC Educational Resources Information Center

Arslan, Halit; Sahin, Ismail; Akturk, Ahmet Oguz; Celik, Ismail

2014-01-01

Today, the means of following the developments in the area of science and technology is to keep up with the pace of the advancements in this area. As is in every profession, apart from their personal efforts, the training of teachers in the period after they start their careers is only possible through in-service training. The aim of the present…

Initial Results: An Ultra-Low-Background Germanium Crystal Array

DTIC Science & Technology

2010-09-01

data (focused on γ -γ coincidence signatures) (Smith et al., 2004) and the Multi- Isotope Coincidence Analysis code (MICA) (Warren et al., 2006). The...The follow-on “CASCADES” project aims to develop a multicoincidence data- analysis package and make robust fission-product demonstration measurements...sensitivity. This effort is focused on improving gamma analysis capabilities for nuclear detonation detection (NDD) applications, e.g., nuclear treaty

Europlanet Prize for Public Engagement

NASA Astrophysics Data System (ADS)

Fouchet, Thierry

2016-10-01

The Europlanet Prize for Public Engagement with Planetary Science is awarded annually. Through the Prize, Europlanet aims to recognise achievements in engaging European citizens with planetary science and to raise the profile of outreach within the scientific community. It is awarded to individuals or groups who have developed innovative practices in planetary science communication and whose efforts have significantly contributed to a wider public engagement with planetary science.

Around Marshall

NASA Image and Video Library

2003-05-01

Students at Williams Technology Middle School in Huntsville were featured in a new segment of NASA CONNECT, a video series aimed to enhance the teaching of math, science, and technology to middle school students. The segment premiered nationwide May 15, 2003, and helped viewers understand Sir Isaac Newton's first, second, and third laws of gravity and how they relate to NASA's efforts in developing the next generation of space transportation.

Hypersonic research engine project. Phase 2: Aerothermodynamic integration model development

NASA Technical Reports Server (NTRS)

Jilly, L. F. (Editor)

1970-01-01

The analytical effort was directed towards (1) completing the design of the combustor exit instrumentation assembly, (2) analyzing the coolant flow distribution of the cowl leading edge tip section, (3) determining effects of purge gas pressure on AIM performance analysis, and (4) analyzing heat transfer and associated stress problems related to the cowl leading edge tip section and the nozzle shroud assembly for test conditions.

Efforts to Improve Teacher Competence in Developing a Lesson Plan through Sustainable Guidance in SMKN 1 Mamuju

ERIC Educational Resources Information Center

Sudirman

2017-01-01

This study aims to improve the competence of teachers in preparing a lesson plan through continuous guidance in SMK 1 Mamuju, West Sulawesi province. Action research school is implemented through two cycles to see an increase in the competence of teachers write eleven components in the lesson plan. In the first cycle (first) all Master (twelve)…

Building a Networked Improvement Community to Promote Equitable, Coherent Systems of Science Education: How a State-Level Team Can Support District-Level Change Efforts

ERIC Educational Resources Information Center

Penuel, William R.; Shaw, Sam; Bell, Philip; Hopkins, Megan; Neill, Tiffany; Farrell, Caitlin C.

2018-01-01

This paper describes a Networked Improvement Community comprised of a network of 13 states focused on improving coherence and equity in state systems of science education. Grounded in principles of improvement science adapted from healthcare, we are developing and testing resources for formative assessment in science, with the aim of developing…

Environmental Action and Student Environmental Leaders: Exploring the Influence of Environmental Attitudes, Locus of Control, and Sense of Personal Responsibility

ERIC Educational Resources Information Center

Ernst, Julie; Blood, Nathaniel; Beery, Thomas

2017-01-01

The Student Climate and Conservation Congress (SC3) is a joint educational effort between the United States Fish and Wildlife Service and the Green Schools Alliance that aims to develop the next generation of conservation leaders through fostering action competence in youth. Data from SC3 participants was used to investigate four predictors of…

Effectiveness and implementation of a community-based prevention programme targeting anabolic androgenic steroid use in gyms: study protocol of a quasi-experimental control group study.

PubMed

Molero, Yasmina; Gripenberg, Johanna; Bakshi, Ann-Sofie

2016-01-01

During the past decades, concerns about increased anabolic androgenic steroid (AAS) use among recreational sportspeople have been raised, yet there is a paucity of AAS prevention efforts targeting this group. Accordingly, doping prevention efforts aimed at gyms have been recommended. The overall objective of the present project is to examine a prevention programme named 100% Pure Hard Training (100% PHT), which targets AAS use among recreational sportspeople training in gyms. Specifically, the project aims to: 1) assess the prevalence of AAS, and its associations with alcohol, illicit drugs, and nutritional supplements use; 2) examine whether 100% PHT can decrease AAS use in gyms, and 3) provide insights into which factors facilitate and/or impede implementation of the programme. The intervention group consists of 27 gyms, and 27 gyms serve as controls. Intervention gyms take part in 100% PHT, a community-based programme involving several components: (a) training of key stakeholders (i.e., gym staff, gym owners, local police, and municipal prevention coordinators) regarding AAS use; (b) developing an action plan for AAS prevention for each gym; (c) certification of gyms that follow 100% PHT; (d) cooperative relationship between stakeholders; (e) annual follow-up of gyms. The project consists of two studies: Study A will examine the prevalence of AAS use and the effectiveness of 100% PHT (aims 1 and 2), and data for Study A will be collected using questionnaires distributed to gym attendees at two assessment points: baseline (pre-intervention) and follow-up (post-intervention). Study B will evaluate the implementation of 100% PHT (aim 3), and semi-structured interviews with participating stakeholders will be carried out post-intervention. Knowledge gained from the present project can be used to develop community-based doping prevention efforts aimed at recreational sportspeople training in gyms. Furthermore, it can provide insights into which factors are important for successful implementation of AAS prevention programmes that target gyms. Results are also expected to yield information on the prevalence of AAS use as well as associations between the use of AAS and other licit and illicit substances, including nutritional supplements, among recreational sportspeople. The study was registered retrospectively at isrctn.com (Identifier: ISRCTN11655041; Registration date: 3 November 2016;).

Prediction of forces and moments for flight vehicle control effectors: Workplan

NASA Technical Reports Server (NTRS)

Maughmer, Mark D.

1989-01-01

Two research activities directed at hypersonic vehicle configurations are currently underway. The first involves the validation of a number of classical local surface inclination methods commonly employed in preliminary design studies of hypersonic flight vehicles. Unlike studies aimed at validating such methods for predicting overall vehicle aerodynamics, this effort emphasizes validating the prediction of forces and moments for flight control studies. Specifically, several vehicle configurations for which experimental or flight-test data are available are being examined. By comparing the theoretical predictions with these data, the strengths and weaknesses of the local surface inclination methods can be ascertained and possible improvements suggested. The second research effort, of significance to control during take-off and landing of most proposed hypersonic vehicle configurations, is aimed at determining the change due to ground effect in control effectiveness of highly swept delta planforms. Central to this research is the development of a vortex-lattice computer program which incorporates an unforced trailing vortex sheet and an image ground plane. With this program, the change in pitching moment of the basic vehicle due to ground proximity, and whether or not there is sufficient control power available to trim, can be determined. In addition to the current work, two different research directions are suggested for future study. The first is aimed at developing an interactive computer program to assist the flight controls engineer in determining the forces and moments generated by different types of control effectors that might be used on hypersonic vehicles. The first phase of this work would deal in the subsonic portion of the flight envelope, while later efforts would explore the supersonic/hypersonic flight regimes. The second proposed research direction would explore methods for determining the aerodynamic trim drag of a generic hypersonic flight vehicle and ways in which it can be minimized through vehicle design and trajectory optimization.

Potential reduction of non-residential solid waste in Sukomanunggal district West Surabaya

NASA Astrophysics Data System (ADS)

Warmadewanthi, I. D. A. A.; Reswari, S. A.

2018-01-01

Sukomanunggal district a development unit 8 with the designation as a regional trade and services, industrial, education, healthcare, offices, and shopping center. The development of this region will make an increasing solid waste generation, especially waste from non-residential facilities. The aims of this research to know the potential reduction of waste source. The method used is the Likert scale questionnaire to determine the knowledge, attitude, and behavior of non-residential facilities manager. Results from this research are the existing reduction of non-residential solid waste is 5.34%, potential reduction of the waste source is optimization of plastic and paper waste with the reduction rate up to 19,52%. The level of public participation existing amounted to 46.79% with a willingness to increase recycling efforts amounted to 72.87%. Efforts that can be developed to increase public awareness of 3R are providing three types of bins, modification of solid waste collection schedule according to a type of waste that has been sorted, the provision of the communal bin.

The Ecology of Sustainable Implementation: Reflection on a 10-Year Case History Illustration.

PubMed

Rimehaug, Tormod

2014-01-01

The primary aim of this paper is to illustrate the strategic and ecological nature of implementation. The ultimate aim of implementation is not dissemination but sustainability beyond the implementation effort. A case study is utilized to illustrate these broad and long-term perspectives of sustainable implementation based on qualitative analyses of a 10-year implementation effort. The purveyors aimed to develop selective community prevention services for children in families burdened by parental psychiatric or addictive problems. Services were gradually disseminated to 23 sites serving 40 municipalities by 2013. Up to 2013, only one site terminated services after initial implementation. Although many sites suspended services for shorter periods, services are still offered at 22 sites. This case analysis is based on project reports, user evaluations, practitioner interviews, and service statistics. The paper focuses on the analyses and strategies utilized to cope with quality decay and setbacks as well as progress and success in disseminating and sustaining the services and their quality. Low-cost multilevel strategies to implement services at the community level were organized by a prevention unit in child psychiatry, supervised by a university department (purveyors). The purveyors were also involved in national and international collaboration and development. Multilevel strategies included manualized intervention, in-practice training methods, organizational responsibility, media strategies, service evaluation, staff motivation maintenance, quality assurance, and proposals for new law regulations. These case history aspects will be discussed in relation to the implementation literature, focusing on possible applicability across settings.

Development and Testing of Carbon-Carbon Nozzle Extensions for Upper Stage Liquid Rocket Engines

NASA Technical Reports Server (NTRS)

Valentine, Peter G.; Gradl, Paul R.; Greene, Sandra E.

2017-01-01

Carbon-carbon (C-C) composite nozzle extensions are of interest for use on a variety of launch vehicle upper stage engines and in-space propulsion systems. The C-C nozzle extension technology and test capabilities being developed are intended to support National Aeronautics and Space Administration (NASA) and Department of Defense (DOD) requirements, as well as those of the broader Commercial Space industry. For NASA, C-C nozzle extension technology development primarily supports the NASA Space Launch System (SLS) and NASA's Commercial Space partners. Marshall Space Flight Center (MSFC) efforts are aimed at both (a) further developing the technology and databases needed to enable the use of composite nozzle extensions on cryogenic upper stage engines, and (b) developing and demonstrating low-cost capabilities for testing and qualifying composite nozzle extensions. Recent, on-going, and potential future work supporting NASA, DOD, and Commercial Space needs will be discussed. Information to be presented will include (a) recent and on-going mechanical, thermal, and hot-fire testing, as well as (b) potential future efforts to further develop and qualify domestic C-C nozzle extension solutions for the various upper stage engines under development.

Biomaterial delivery of morphogens to mimic the natural healing cascade in bone

PubMed Central

Mehta, Manav; Schmidt-Bleek, Katharina; Duda, Georg N; Mooney, David J

2012-01-01

Complications in treatment of large bone defects using bone grafting still remain. Our understanding of the endogenous bone regeneration cascade has inspired the exploration of a wide variety of growth factors (GFs) in an effort to mimic the natural signaling that controls bone healing. Biomaterial-based delivery of single exogenous GFs has shown therapeutic efficacy, and this likely relates to its ability to recruit and promote replication of cells involved in tissue development and the healing process. However, as the natural bone healing cascade involves the action of multiple factors, each acting in a specific spatiotemporal pattern, strategies aiming to mimic the critical aspects of this process will likely benefit from the usage of multiple therapeutic agents. This article reviews the current status of approaches to deliver single GFs, as well as ongoing efforts to develop sophisticated delivery platforms to deliver multiple lineage-directing morphogens (multiple GFs) during bone healing. PMID:22626978

Future orientation: a construct with implications for adolescent health and wellbeing.

PubMed

Johnson, Sarah R Lindstrom; Blum, Robert W; Cheng, Tina L

2014-01-01

Multidisciplinary research has supported a relationship between adolescent future orientation (the ability to set future goals and plans) and positive adolescent health and development outcomes. Many preventive strategies - for example, contracepting, exercising - are based on taking actions in the present to avoid unwanted or negative future consequences. However, research has been hampered by unclear and often divergent conceptualizations of the future orientation construct. The present paper aims to integrate previous conceptual and operational definitions into a conceptual framework that can inform programs and services for youth and efforts to evaluate future orientation as a target for intervention. Recommendations focus on furthering the study of the construct through measurement synthesis as well as studies of the normative development of future orientation. Also suggested is the need to pair environmental intervention strategies with individual level efforts to improve future orientation in order to maximize benefits.

Future Orientation: A Construct with Implications for Adolescent Health and Wellbeing

PubMed Central

Lindstrom Johnson, Sarah; Blum, Robert W; Cheng, Tina L.

2016-01-01

Multi-disciplinary research has supported a relationship between adolescent future orientation (the ability to set future goals and plans) and positive adolescent health and development outcomes. Many preventive strategies—for example contracepting, exercising—are based on taking actions in the present to avoid unwanted or negative future consequences. However, research has been hampered by unclear and often divergent conceptualizations of the future orientation construct. The present paper aims to integrate previous conceptual and operational definitions into a conceptual framework that can inform programs and services for youth and efforts to evaluate future orientation as a target for intervention. Recommendations focus on furthering the study of the construct through measurement synthesis as well as studies of the normative development of future orientation. Also suggested is the need to pair environmental intervention strategies with individual level efforts to improve future orientation in order to maximize benefits. PMID:24523304

The current state of GPCR-based drug discovery to treat metabolic disease.

PubMed

Sloop, Kyle W; Emmerson, Paul J; Statnick, Michael A; Willard, Francis S

2018-02-02

One approach of modern drug discovery is to identify agents that enhance or diminish signal transduction cascades in various cell types and tissues by modulating the activity of GPCRs. This strategy has resulted in the development of new medicines to treat many conditions, including cardiovascular disease, psychiatric disorders, HIV/AIDS, certain forms of cancer and Type 2 diabetes mellitus (T2DM). These successes justify further pursuit of GPCRs as disease targets and provide key learning that should help guide identifying future therapeutic agents. This report reviews the current landscape of GPCR drug discovery with emphasis on efforts aimed at developing new molecules for treating T2DM and obesity. We analyse historical efforts to generate GPCR-based drugs to treat metabolic disease in terms of causal factors leading to success and failure in this endeavour. © 2018 The British Pharmacological Society.

Rational drug design paradigms: the odyssey for designing better drugs.

PubMed

Kellici, Tahsin; Ntountaniotis, Dimitrios; Vrontaki, Eleni; Liapakis, George; Moutevelis-Minakakis, Panagiota; Kokotos, George; Hadjikakou, Sotiris; Tzakos, Andreas G; Afantitis, Antreas; Melagraki, Georgia; Bryant, Sharon; Langer, Thierry; Di Marzo, Vincenzo; Mavromoustakos, Thomas

2015-01-01

Due to the time and effort requirements for the development of a new drug, and the high attrition rates associated with this developmental process, there is an intense effort by academic and industrial researchers to find novel ways for more effective drug development schemes. The first step in the discovery process of a new drug is the identification of the lead compound. The modern research tendency is to avoid the synthesis of new molecules based on chemical intuition, which is time and cost consuming, and instead to apply in silico rational drug design. This approach reduces the consumables and human personnel involved in the initial steps of the drug design. In this review real examples from our research activity aiming to discover new leads will be given for various dire warnings diseases. There is no recipe to follow for discovering new leads. The strategy to be followed depends on the knowledge of the studied system and the experience of the researchers. The described examples constitute successful and unsuccessful efforts and reflect the reality which medicinal chemists have to face in drug design and development. The drug stability is also discussed in both organic molecules and metallotherapeutics. This is an important issue in drug discovery as drug metabolism in the body can lead to various toxic and undesired molecules.

Issues impacting therapeutic outcomes in pediatric patients: an overview.

PubMed

Kalra, Atin; Goindi, Shishu

2014-01-01

The quest for achieving optimal therapeutic outcomes in pediatric patients has evaded the healthcare professionals for long and often lack of child specific dosage forms and the associated events that follow with it have been considered to be major contributor towards suboptimal outcomes. Consequently, there have been sustained efforts over the years to address this issue with the enactment of legislations like Best Pharmaceutical for Children Act (BPCA), Pediatric Research Equity Act (PREA) and Pediatric Regulation by European Union (EU) to incentivise the participation of pharmaceutical industry towards development of child friendly dosage forms. Initiatives taken in past by organisations like World Health Organisation (WHO) and Drugs for Neglected Diseases Initiative (DNDi) to spur the development of child friendly dosage forms has helped to address issues pertaining to management of Human Immunodeficiency Virus (HIV) and malaria in pediatric patients. Present efforts aimed at developing child friendly dosage forms include oro-dispersible platforms including thin films and mini-tablets. Despite these leaps and advancements in developing better dosage forms for children, lower therapeutic outcomes in pediatric patients continue to remain an unresolved issue because of detrimental effects of additional factors such as parents understanding of label instructions and complexities involved in executing pediatric clinical studies thus requiring a concerted effort from pharmaceutical companies, academic researchers, parents and healthcare providers to work for better treatment outcomes in children.

Advances in Projection Moire Interferometry Development for Large Wind Tunnel Applications

NASA Technical Reports Server (NTRS)

Fleming, Gary A.; Soto, Hector L.; South, Bruce W.; Bartram, Scott M.

1999-01-01

An instrument development program aimed at using Projection Moire Interferometry (PMI) for acquiring model deformation measurements in large wind tunnels was begun at NASA Langley Research Center in 1996. Various improvements to the initial prototype PMI systems have been made throughout this development effort. This paper documents several of the most significant improvements to the optical hardware and image processing software, and addresses system implementation issues for large wind tunnel applications. The improvements have increased both measurement accuracy and instrument efficiency, promoting the routine use of PMI for model deformation measurements in production wind tunnel tests.

Climatic response variability and machine learning: development of a modular technology framework for predicting bio-climatic change in pacific northwest ecosystems"

NASA Astrophysics Data System (ADS)

Seamon, E.; Gessler, P. E.; Flathers, E.

2015-12-01

The creation and use of large amounts of data in scientific investigations has become common practice. Data collection and analysis for large scientific computing efforts are not only increasing in volume as well as number, the methods and analysis procedures are evolving toward greater complexity (Bell, 2009, Clarke, 2009, Maimon, 2010). In addition, the growth of diverse data-intensive scientific computing efforts (Soni, 2011, Turner, 2014, Wu, 2008) has demonstrated the value of supporting scientific data integration. Efforts to bridge this gap between the above perspectives have been attempted, in varying degrees, with modular scientific computing analysis regimes implemented with a modest amount of success (Perez, 2009). This constellation of effects - 1) an increasing growth in the volume and amount of data, 2) a growing data-intensive science base that has challenging needs, and 3) disparate data organization and integration efforts - has created a critical gap. Namely, systems of scientific data organization and management typically do not effectively enable integrated data collaboration or data-intensive science-based communications. Our research efforts attempt to address this gap by developing a modular technology framework for data science integration efforts - with climate variation as the focus. The intention is that this model, if successful, could be generalized to other application areas. Our research aim focused on the design and implementation of a modular, deployable technology architecture for data integration. Developed using aspects of R, interactive python, SciDB, THREDDS, Javascript, and varied data mining and machine learning techniques, the Modular Data Response Framework (MDRF) was implemented to explore case scenarios for bio-climatic variation as they relate to pacific northwest ecosystem regions. Our preliminary results, using historical NETCDF climate data for calibration purposes across the inland pacific northwest region (Abatzoglou, Brown, 2011), show clear ecosystems shifting over a ten-year period (2001-2011), based on multiple supervised classifier methods for bioclimatic indicators.

Multispectral Linear Array detector technology

NASA Astrophysics Data System (ADS)

Tower, J. R.; McCarthy, B. M.; Pellon, L. E.; Strong, R. T.; Elabd, H.

1984-01-01

The Multispectral Linear Array (MLA) program sponsored by NASA has the aim to extend space-based remote sensor capabilities. The technology development effort involves the realization of very large, all-solid-state, pushbroom focal planes. The pushbroom, staring focal planes will contain thousands of detectors with the objective to provide two orders of magnitude improvement in detector dwell time compared to present Landsat mechanically scanned systems. Attenton is given to visible and near-infrared sensor development, the shortwave infrared sensor, aspects of filter technology development, the packaging concept, and questions of system performance. First-sample, four-band interference filters have been fabricated successfully, and a hybrid packaging technology is being developed.

Restoring the biological crust cover of soils across biomes in arid North America

NASA Astrophysics Data System (ADS)

Garcia-Pichel, Ferran; Antoninka, Anita; Bowker, Matthew; Giraldo Silva, Ana; Nelson, Corey; Velasco Ayuso, Sergio; Barger, Nichole; Belnap, Jayne; Reed, Sasha; Duniway, Michael

2015-04-01

Biological soil crust communities provide important ecosystem services to arid lands, particularly regarding soil fertility and stability against erosion. In North America, and in many other areas of the globe, increasingly intense human activities, ranging from cattle grazing to military training, have resulted in the significant deterioration of biological soil surface cover of soils. With the intent of attaining sustainable land use practices, we are conducting a 5-year, multi-institutional research effort to develop feasible soil crusts restoration strategies for US military lands. We are including field sites of varying climatic regions (warm and cold deserts, in the Chihuahuan Desert and in the Great Basin, respectively) and varying edaphic characteristics (sandy and silty soils in each). We have multiple aims. First, we aim to establishing effective "biocrust nurseries" that produce viable and pedigreed inoculum, as a supply center for biocrust restoration and for research and development. Second, we aim to develop optimal field application methods of biocrust inoculum in a series of field trials. Currently in our second year of research, we will be reporting on significant advances made on optimizing methodologies for the large-scale supply of inoculum based on a) pedigreed laboratory cultures that match the microbial community structure of the original sites, and b) "in soil" biomass enhancement, whereby small amounts of local crusts are nursed under greenhouse conditions to yield hundred-fold increases in biomass without altering significantly community structure. We will also report on field trials for methodologies in field application, which included shading, watering, application of chemical polymers, and soil surface roughening. In a soon-to-be-initiated effort we also aim to evaluate soil and plant responses to biocrust restoration with respect to plant community structure, soil fertility, and soil stability, in multi-factorial field experiments. An important part of the plan will be to construct effective channels for sharing challenges and solutions in biocrust restoration with military and federal land managers.

NASA and Superalloys: A Customer, a Participant, and a Referee

NASA Technical Reports Server (NTRS)

Nathal, Michael V.

2008-01-01

NASA has had a long history of research and development in the field of superalloys. These efforts have continued today, where the latest advancements in turbine disk and blade technologies are being developed. Although NASA does support military flight systems, its predominant role is in supporting civilian air transportation systems, and thus has goals for improving fuel efficiency, emissions, noise, and safety of today s aircraft. NASA has traditionally served several distinct but complimentary roles as participants in multi-disciplinary research teams, as customers who fund research and development efforts at industry and universities, and as referees who can address broad issues that affect the entire aeronautics community. Because of our longer range viewpoint, we can take on higher risk, higher reward research topics. NASA can also serve as an intermediary between the basic research performed primarily at universities and the development efforts emphasized by industry. By interacting with individual companies, NASA can identify areas of general interest and problems common to a large portion of the aeronautics community, and devise programs aimed at solving these problems. In space missions, NASA is a direct customer responsible for developing vehicles. In the case of the Space Shuttle, NASA has worked with various contractors to design and build numerous components out of superalloys. Another fascinating area for the use of superalloys is in power systems for long life applications in space. Potential missions include providing electric power for deep space missions, surface rovers, including lunar and Mars, and stationary power generators on the lunar surface.

The Development of Sensor Applications in the Sectors of Energy and Environment in Italy, 1976–2015

PubMed Central

Di Francia, Girolamo

2017-01-01

Although sensor technologies have been developing quite similarly all over the world, the investigation of their applications has been more affected by the specific industrial and economic characteristics of each country. This paper aims to investigate the development of applications based on sensor devices in the sectors of energy and the environment, in Italy, throughout the last forty years (1976–2015), examining the most relevant papers published by Italian R & D groups working in this field. Italy depends on foreign imports for more than 80% of its primary energy needs, and this has directed the research effort on the development of sensor applications both to improve load shaping and consumers’ awareness and to develop specific equipment to maximize renewable energy production. Similarly, for the environment sector, there are increasing efforts to develop solutions to support a more and more capillary control of the environment itself using a cooperative approach. In both the sectors it seems that the solutions proposed can help to relieve the structural problems that Italy suffers and that the scientific and technical results obtained so far also have significant international relevance. PMID:28387739

Farmers’s perception and strategies for the development of sustainable livelihoods in disaster prone areas

NASA Astrophysics Data System (ADS)

Anantanyu, S.; Suwarto; Suminah

2018-03-01

Empowerment is a strategy to develop and build economy and community in both physically and mentally. One effort is to help generate a plan for community development in disaster-prone areas. For that, this study aims to develop farmers profile, to describe farmer perception towards farming effort and to formulate the empowerment strategies in the development of sustainable livelihoods in disaster prone areas. This study uses mixed methods. Farmers population use in this study were live in two villages of landslides prone areas, that are Beruk and Wonorejo which belongs Jatiyoso Subdistrict Karanganyar regency (Central Java). In depth structured interview was conducted to 150 farmers under Focus Group Discussion (FGD) followed with. data analysis using SWOT analysis. The results showed level of farm management is in anxiety level, perception of farmers toward the availability of agricultural inputs is at a reasonable level and the agricultural information becomes the reduction factors. The result of QSPM matrix calculation through SWOT analysis on livelihood of agricultural, resulting some strategy according to the priority level that are development of conservation farming, strengthening the farmers capacity in agricultural products processing, strengthening farmer groups and improving the performance of agriculture extensionist.

ExMC Work Prioritization Process

NASA Technical Reports Server (NTRS)

Simon, Matthew

2015-01-01

Last year, NASA's Human Research Program (HRP) introduced the concept of a "Path to Risk Reduction" (PRR), which will provide a roadmap that shows how the work being done within each HRP element can be mapped to reducing or closing exploration risks. Efforts are currently underway within the Exploration Medical Capability (ExMC) Element to develop a structured, repeatable process for prioritizing work utilizing decision analysis techniques and risk estimation tools. The goal of this effort is to ensure that the work done within the element maximizes risk reduction for future exploration missions in a quantifiable way and better aligns with the intent and content of the Path to Risk Reduction. The Integrated Medical Model (IMM) will be used to identify those conditions that are major contributors of medical risk for a given design reference mission. For each of these conditions, potential prevention, screening, diagnosis, and treatment methods will be identified. ExMC will then aim to prioritize its potential investments in these mitigation methods based upon their potential for risk reduction and other factors such as vehicle performance impacts, near term schedule needs, duplication with external efforts, and cost. This presentation will describe the process developed to perform this prioritization and inform investment discussions in future element planning efforts. It will also provide an overview of the required input information, types of process participants, figures of merit, and the expected outputs of the process.

Development and Hover Testing of the Active Elevon Rotor

DTIC Science & Technology

2012-05-01

typically aimed at reducing vibration, improving rotor performance, and/or reducing blade -vortex interaction (BVI) or in-plane noise . These efforts...will become unstable, either through a 1-DOF (degree of freedom) flutter or some kind of aeroservoelastic coupling with the rotor blade and/or wake ... blade CAEAs did exhibit electrical arcing (audible noise ), even at oscillatory voltages below ±200 V. This arcing/ noise suggests a latent deficiency

Development of Personalized Cancer Therapy for Men with Advanced Prostate Cancer

DTIC Science & Technology

2017-10-01

cascade is significantly associated with the beta isoform. Based on these studies , we hypothesize that FGFR1 alpha and beta confers different phenotypes...Goals: This is an open label study to determine the effect of Alpharadin on the bone marrow microenvironment in patients with castrate resistant...and analysis of studies using high-throughput technologies. Effort added. Specific Aims: Same as above. Role: Co-Investigator Prostate Moon Shot

The Holdridge life zones of the conterminous United States in relation to ecosystem mapping

Treesearch

A.E. Lugo; S. L. Brown; R. Dodson; T. S Smith; H. H. Shugart

1999-01-01

Aim Our main goals were to develop a map of the life zones for the conterminous United States, based on the Holdridge Life Zone system, as a tool for ecosystem mapping, and to compare the map of Holdridge life zones with other global vegetation classification and mapping efforts. Location The area of interest is the forty-eight contiguous states of the United States....

Analyzing Item Generation with Natural Language Processing Tools for the "TOEIC"® Listening Test. Research Report. ETS RR-17-52

ERIC Educational Resources Information Center

Yoon, Su-Youn; Lee, Chong Min; Houghton, Patrick; Lopez, Melissa; Sakano, Jennifer; Loukina, Anastasia; Krovetz, Bob; Lu, Chi; Madani, Nitin

2017-01-01

In this study, we developed assistive tools and resources to support TOEIC® Listening test item generation. There has recently been an increased need for a large pool of items for these tests. This need has, in turn, inspired efforts to increase the efficiency of item generation while maintaining the quality of the created items. We aimed to…

Iran With Nuclear Weapons: Anticipating the Consequences for U.S. Policy

DTIC Science & Technology

2008-09-01

per response, including the time for reviewing instructions, searching existing data sources, gathering and maintaining the data needed, and completing...and, at the same time , develop and/ or acquire more sophisticated defensive technologies to protect high-value aim-points, including nuclear weapons...efforts to shape the political agendas of its Persian Gulf neighbors at a time when allies or coalition partners might not agree about the nature and

Huntsville Area Students Appear in Episode of NASA CONNECT

NASA Technical Reports Server (NTRS)

2003-01-01

Students at Williams Technology Middle School in Huntsville were featured in a new segment of NASA CONNECT, a video series aimed to enhance the teaching of math, science, and technology to middle school students. The segment premiered nationwide May 15, 2003, and helped viewers understand Sir Isaac Newton's first, second, and third laws of gravity and how they relate to NASA's efforts in developing the next generation of space transportation.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lee, Dominic F.; Burwell, Malcolm; Stillman, H.

This report documents the findings at an Ultraconductive Copper Strategy Meeting held on March 11, 2015 in Washington DC. The aim of this meeting was to bring together researchers of ultraconductive copper in the U.S. to identify and prioritize critical non-proprietary research activities that will enhance the understanding in the material and accelerate its development into practical conductors. Every effort has been made to ensure that the discussion and findings are accurately reported in this document.

Improved Training Method for Rapid Rehabilitation of Amputees

DTIC Science & Technology

2015-05-01

Falls Overall Project Summary This report describes a four year research effort to develop and test a novel training technique aimed at increasing...month post training assessment. One subject moved after completing the training and did not return for follow-up. Three subjects failed to respond to...training (n=5) Reasons: Moved, revisions, suicide attempt, time conflict Completed Training (n= 20) Completed post - testing (n=20). Lost to

New Trends in Two-Way Time and Frequency Transfer via Satellite

DTIC Science & Technology

1999-12-01

Recent developments performed with SATRE two-way time transfer ( TWSTFT ) modems resulted in significant performance upgrades and operational...improvements of the TWSTFT method These are aimed to reduce : manpower effort and to provide reliable, real-time data via a centralized monitoring and...collection have been used throughout the experiment INTRODUCTION Two-Way Time and Frequency Transfer via Satellite ( TWSTFT ) is a well established method to

'Renewables-Friendly' Grid Development Strategies: Experience in the United States, Potential Lessons for China (Chinese Translation) (in Chinese)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hurlbut, David; Zhou, Ella; Porter, Kevin

2015-10-03

This is a Chinese translation of NREL/TP-6A20-64940. This report aims to help China's reform effort by providing a concise summary of experience in the United States with 'renewables-friendly' grid management, focusing on experiences that might be applicable to China. It focuses on utility-scale renewables and sets aside issues related to distributed generation.

Revisiting the AIDS Epidemic in Pakistan: Where We Stand and What We Must Aim For.

PubMed

Dar, Hamza Arshad; Mubashir, Areeba; Adil, Manal; Farzeen, Aiman; Naseer, Hasaan; Ayub, Gohar; Mansoor, Sajid; Javed, Aneela

2017-10-01

Human immunodeficiency virus type 1 (HIV-1) is the major cause of acquired immunodeficiency syndrome (AIDS) in humans, where the immune system totally succumbs to the virus. A large proportion of the AIDS infected belong to developing countries and AIDS prevalence is intensified by severe poverty, malnutrition, and famine; fatal illnesses with a scorn shortage of medical amenities complemented with the lack of education and development. Current Pakistani health system setting is in a dire need of improvement. Low literacy rates, high birth rates, and associated maternal mortality plus a lack of clean drinking water and appropriate sanitation system have a serious impact on general living conditions contributing to a relatively short lifespan. HIV is, therefore, becoming a growing health concern in Pakistan with a rapid rise in the reported cases. AIDS is most prevalent among injection drug users (IDUs), male/female sex workers, and unchecked deported migrant workforce. To combat this virus, the Pakistan Government has been working hard over the past few years with local bodies and international organizations in an effort to combat this menace. This review aims to discuss the risk factors for the rise of this epidemic in the country and the recommendations, efforts to be done to address this alarming issue.

Access to Drinking Water and Sanitation in Rural Kazakhstan

PubMed Central

Tussupova, Kamshat; Hjorth, Peder; Berndtsson, Ronny

2016-01-01

The Sustainable Development Goals (SDGs) require nations to ensure adequate water supply for all. For Kazakhstan, this means that rural areas will need much stronger attention as they have been rather neglected in efforts to comply with the Millennium Development Goals (MDGs). This study aims to establish a baseline data concerning the current situation in villages that will need interventions according to the SDGs. The study was performed by means of questionnaires. The results should be seen as initial guidelines that can help to illuminate some of the uncounted challenges in future efforts to meet the SDG targets. As hardly any information exists about sanitation in rural Kazakhstan, the study essentially focuses on water services. The results show that 65% of rural dwellers want to connect and pay for the piped water supply. At the same time, about 80% have toilets outside their home. Consequently, the water program aiming at providing 80% of rural people with access to tap water from a centralized piped system will not be possible. However, by carefully managing the existing water supply and sanitation system in joint collaboration with the local users, significant progress can be made. The present results show the important first steps that need to be taken in this direction. PMID:27834889

Researching Together: A CTSA Partnership of Academicians and Communities for Translation

PubMed Central

Nearing, Kathryn; Felzien, Maret; Green, Larry; Calonge, Ned; Pineda‐Reyes, Fernando; Jones, Grant; Tamez, Montelle; Miller, Sara; Kramer, Andrew

2013-01-01

Abstract Background The Colorado Clinical and Translational Sciences Institute (CCTSI) aims to translate discovery into clinical practice. The Partnership of Academicians and Communities for Translation (PACT) represents a robust campus–community partnership. Methods The CCTSI collected data on all PACT activities including meeting notes, staff activity logs, stakeholder surveys and interviews, and several key component in‐depth evaluations. Data analysis by Evaluation and Community Engagement Core and PACT Council members identified critical shifts that changed the trajectory of community engagement efforts. Results Ten “critical shifts” in six broad rubrics created change in the PACT. Critical shifts were decision points in the development of the PACT that represented quantitative and qualitative changes in the work and trajectory. Critical shifts occurred in PACT management and leadership, financial control and resource allocation, and membership and voice. Discussion The development of a campus–community partnership is not a smooth linear path. Incremental changes lead to major decision points that represent an opportunity for critical shifts in developmental trajectory. We provide an enlightening, yet cautionary, tale to others considering a campus–community partnership so they may prepare for crucial decisions and critical shifts. The PACT serves as a genuine foundational platform for dynamic research efforts aimed at eliminating health disparities. PMID:24127922

Access to Drinking Water and Sanitation in Rural Kazakhstan.

PubMed

Tussupova, Kamshat; Hjorth, Peder; Berndtsson, Ronny

2016-11-09

The Sustainable Development Goals (SDGs) require nations to ensure adequate water supply for all. For Kazakhstan, this means that rural areas will need much stronger attention as they have been rather neglected in efforts to comply with the Millennium Development Goals (MDGs). This study aims to establish a baseline data concerning the current situation in villages that will need interventions according to the SDGs. The study was performed by means of questionnaires. The results should be seen as initial guidelines that can help to illuminate some of the uncounted challenges in future efforts to meet the SDG targets. As hardly any information exists about sanitation in rural Kazakhstan, the study essentially focuses on water services. The results show that 65% of rural dwellers want to connect and pay for the piped water supply. At the same time, about 80% have toilets outside their home. Consequently, the water program aiming at providing 80% of rural people with access to tap water from a centralized piped system will not be possible. However, by carefully managing the existing water supply and sanitation system in joint collaboration with the local users, significant progress can be made. The present results show the important first steps that need to be taken in this direction.

Two Papers on Canadian Indians; Education and Economic Development: The Case of Indian Reserves in Canada. [and] The Capitalization of a Traditional Pursuit: The Case of Wild Rice in Manitoba. Center for Settlement Studies, Series 5: Occasional Papers Nos. 5 and 6.

ERIC Educational Resources Information Center

Deprez, Paul; Lithman, Yngve Georg

The first paper aims to give a certain relativity to the significance of education and to indicate the limitations of any educational effort. The thinking underlying the current approach to the economic development of native communities and reserves is discussed as well as the implications and consequences of such thinking. It is argued that the…

Corporate visual identity: a case in hospitals.

PubMed

Alkibay, Sanem; Ozdogan, F Bahar; Ermec, Aysegul

2007-01-01

This paper aims to present a perspective to better understand corporate identity through examining the perceptions of Turkish patients and develop a corporate visual identity scale. While there is no study related to corporate identity research on hospitals in Turkey as a developing country, understanding consumer's perceptions about corporate identity efforts of hospitals could provide different perspectives for recruiters. When the hospitals are considered in two different groups as university and state hospitals, the priority of the characteristics of corporate visual identity may change, whereas the top five characteristics remain the same for all the hospitals.

Advanced CO 2 Leakage Mitigation using Engineered Biomineralization Sealing Technologies

DOE Office of Scientific and Technical Information (OSTI.GOV)

Spangler, Lee; Cunningham, Alfred; Phillips, Adrienne

2015-03-31

This research project addresses one of the goals of the DOE Carbon Sequestration Program (CSP). The CSP core R&D effort is driven by technology and is accomplished through laboratory and pilot scale research aimed at new technologies for greenhouse gas mitigation. Accordingly, this project was directed at developing novel technologies for mitigating unwanted upward leakage of carbon dioxide (CO 2) injected into the subsurface as part of carbon capture and storage (CCS) activities. The technology developed by way of this research project is referred to as microbially induced calcite precipitation (MICP).

Microgravity Investigation of Crew Reactions in 0-G (MICR0-G): Ground-Based Development Effort

NASA Technical Reports Server (NTRS)

Newman, Dava J.

2002-01-01

This report describes the technology development of an advanced load sensor ground-based prototype and details the preliminary tests in microgravity during parabolic flights. The research effort is entitled, the Microgravity Investigation and Crew Reactions in 0-G (MICR0-G), a ground-based research effort funded by the National Aeronautics and Space Administration (NASA). The MICR0-G project was a follow-on to the Enhanced Dynamic Load Sensors (EDLS) spaceflight experiment flown on the Russian Space Station Mir. The technology development of the advanced load sensor prototype has been carried out by the Massachusetts Institute of Technology (MIT), with collaboration from Politecnico di Milano University and the Italian Space Agency (ASI). The key hardware of the advanced sensor prototype is a set of two types of load sensors - a hand-hold and foot restraints - similar in appearance to the mobility aids found in the Space Shuttle orbiter to assist the crew in moving inside the spacecraft, but able to measure the applied forces and moments about the x-, y-, and z- axes. The aim of Chapter 1 is to give a brief overview of the report contents. The first section summarizes the previous research efforts on astronaut-induced loads in microgravity. The second section provides information on the MICR0-G research project and the technology development work conducted at MIT. Section 1.3 details the motivation for designing a new generation of load sensors and describes the main enhancements and contributions of the MICR0-G advanced load sensors system compared to the EDLS system. Finally, the last section presents the outline of the report.

Contribution mapping: a method for mapping the contribution of research to enhance its impact

PubMed Central

2012-01-01

Background At a time of growing emphasis on both the use of research and accountability, it is important for research funders, researchers and other stakeholders to monitor and evaluate the extent to which research contributes to better action for health, and find ways to enhance the likelihood that beneficial contributions are realized. Past attempts to assess research 'impact' struggle with operationalizing 'impact', identifying the users of research and attributing impact to research projects as source. In this article we describe Contribution Mapping, a novel approach to research monitoring and evaluation that aims to assess contributions instead of impacts. The approach focuses on processes and actors and systematically assesses anticipatory efforts that aim to enhance contributions, so-called alignment efforts. The approach is designed to be useful for both accountability purposes and for assisting in better employing research to contribute to better action for health. Methods Contribution Mapping is inspired by a perspective from social studies of science on how research and knowledge utilization processes evolve. For each research project that is assessed, a three-phase process map is developed that includes the main actors, activities and alignment efforts during research formulation, production and knowledge extension (e.g. dissemination and utilization). The approach focuses on the actors involved in, or interacting with, a research project (the linked actors) and the most likely influential users, who are referred to as potential key users. In the first stage, the investigators of the assessed project are interviewed to develop a preliminary version of the process map and first estimation of research-related contributions. In the second stage, potential key-users and other informants are interviewed to trace, explore and triangulate possible contributions. In the third stage, the presence and role of alignment efforts is analyzed and the preliminary results are shared with relevant stakeholders for feedback and validation. After inconsistencies are clarified or described, the results are shared with stakeholders for learning, improvement and accountability purposes. Conclusion Contribution Mapping provides an interesting alternative to existing methods that aim to assess research impact. The method is expected to be useful for research monitoring, single case studies, comparing multiple cases and indicating how research can better be employed to contribute to better action for health. PMID:22748169

A study on nonlinear estimation of submaximal effort tolerance based on the generalized MET concept and the 6MWT in pulmonary rehabilitation

PubMed Central

Szczegielniak, Jan; Łuniewski, Jacek; Stanisławski, Rafał; Bogacz, Katarzyna; Krajczy, Marcin; Rydel, Marek

2018-01-01

Background The six-minute walk test (6MWT) is considered to be a simple and inexpensive tool for the assessment of functional tolerance of submaximal effort. The aim of this work was 1) to background the nonlinear nature of the energy expenditure process due to physical activity, 2) to compare the results/scores of the submaximal treadmill exercise test and those of 6MWT in pulmonary patients and 3) to develop nonlinear mathematical models relating the two. Methods The study group included patients with the COPD. All patients were subjected to a submaximal exercise test and a 6MWT. To develop an optimal mathematical solution and compare the results of the exercise test and the 6MWT, the least squares and genetic algorithms were employed to estimate parameters of polynomial expansion and piecewise linear models. Results Mathematical analysis enabled to construct nonlinear models for estimating the MET result of submaximal exercise test based on average walk velocity (or distance) in the 6MWT. Conclusions Submaximal effort tolerance in COPD patients can be effectively estimated from new, rehabilitation-oriented, nonlinear models based on the generalized MET concept and the 6MWT. PMID:29425213

A review of HIV/AIDS system-level interventions

PubMed Central

Bauermeister, José A.; Tross, Susan; Ehrhardt, Anke A.

2010-01-01

The escalating HIV/AIDS epidemic worldwide demands that on-going prevention efforts be strengthened, disseminated, and scaled-up. System-level interventions refer to programs aiming to improve the functioning of an agency as well as the delivery of its services to the community. System-level interventions are a promising approach to HIV/AIDS prevention because they focus on (a) improving the agency’s ability to adopt evidence-based HIV prevention and care programs; (b) develop and establish policies and procedures that maximize the sustainability of on-going prevention and care efforts; and (c) improve decision-making processes such as incorporating the needs of communities into their tailored services. We reviewed studies focusing on system-level interventions by searching multiple electronic abstracting indices, including PsycInfo, PubMed, and ProQuest. Twenty-three studies out of 624 peer-reviewed studies (published from January 1985 to February 2007) met study criteria. Most of the studies focused on strengthening agency infrastructure, while other studies included collaborative partnerships and technical assistance programs. Our findings suggest that system-level interventions are promising in strengthening HIV/AIDS prevention and treatment efforts. Based on our findings, we propose recommendations for future work in developing and evaluating system-level interventions. PMID:18369722

Gender Transformative Approaches to Engaging Men in Gender-Based Violence Prevention: A Review and Conceptual Model.

PubMed

Casey, Erin; Carlson, Juliana; Two Bulls, Sierra; Yager, Aurora

2018-04-01

Engaging men and boys as participants and stakeholders in gender-based violence (GBV) prevention initiatives is an increasingly institutionalized component of global efforts to end GBV. Accordingly, evidence of the impact of men's engagement endeavors is beginning to emerge, particularly regarding interventions aimed at fostering gender equitable and nonviolent attitudes and behaviors among men. This developing evidence base suggests that prevention programs with a "gender transformative" approach, or an explicit focus on questioning gender norms and expectations, show particular promise in achieving GBV prevention outcomes. Interventions targeting attitude and behavior change, however, represent just one kind of approach within a heterogeneous collection of prevention efforts around the globe, which can also include community mobilization, policy change, and social activism. The degree to which gender transformative principles inform this broader spectrum of men's engagement work is unclear. The goals of this article are twofold. First, we offer a conceptual model that captures and organizes a broader array of men's antiviolence activities in three distinct but interrelated domains: (1) initial outreach and recruitment of previously unengaged males, (2) interventions intended to promote gender-equitable attitudes and behavior among men, and (3) gender equity-related social action aimed at eradicating GBV, inclusive of all genders' contributions. Second, we review empirical literature in each of these domains. Across these two goals, we critically assess the degree to which gender transformative principles inform efforts within each domain, and we offer implications for the continuing conceptualization and assessment of efforts to increase men's participation in ending GBV.

We Don't Need a "Geoengineering" Research Program

NASA Astrophysics Data System (ADS)

Caldeira, K.

2011-12-01

Most approaches commonly labeled as 'geoengineering' can be divided into two categories: approaches that attempt to reduce the change in atmospheric composition caused by anthropogenic emissions (commonly labeled CDR, for Carbon Dioxide Removal), and approaches that attempt to reduce the change in climate caused by changes in atmospheric composition (commonly labeled SRM, for Sunlight Reflection Methods or Solar Radiation Management). CDR is relatively uncontroversial (apart from ocean fertilization), and the primary issues are typically cost, effectiveness, local environmental consequences, and verification. In contrast, SRM has provoked much controversy, because large-scale SRM deployments necessarily would affect everyone on this planet. Several proposals have been tabled for SRM-specific or geoengineering-specific research and governance structures, treating SRM or geoengineering research as a thing apart. We should instead view CDR and SRM research as part of a broader continuum of activities aimed at understanding Earth system dynamics and reducing risks associated with climate change. The scope of existing research efforts should be broadened so that CDR and SRM approaches are, at this stage in development, treated as an extension of what we are already doing. What is 'geoengineering research'? A primary need at this time is for expansion of scope of and funding for existing climate-related research efforts. For examples: Scientists studying the role of aerosols in clouds or stratospheric processes can expand the domain of concern to consider effects of intentionally introduced aerosols (and not just natural aerosols and aerosols we introduce as a byproduct of civilization's normal functioning). Scientists studying effects of land-surface change on global and regional climates can expand the domain of concern beyond inadvertent effects to consider effects of land-surface changes undertaken with the intent to affect these climates. Research programs aimed at removing carbon dioxide from power plant flue gases can be broadened to consider industrial approaches to remove carbon dioxide that has already been released to the atmosphere. There appears to be little need for new overarching research structures or institutions at this time for activities for which there are no plans for deployment. Defining the scope of reference of 'geoengineering' and related terms (eg, 'geoengineering experiment') is a linguistic distraction and a waste of time. We should focus instead on substantive issues of primary concern. If our goal is to reduce risk from scientific experiments, then let's develop approaches aimed at governing risky experiments. Governance efforts can be aimed at eliminating unjustified risk independently of whether some people might want to apply labels like 'geoengineering' to those activities. We do not need 'a geoengineering research program'. We need to expand existing research programs to consider a broader range of activities and conditions. We do not need efforts to govern 'geoengineering experiments' although we may need efforts to govern scientific experiments that pose unjustified risks. Let's focus on gaining knowledge and managing risks, and not let our brains be addled by emotionally-charged language.

The Case of Nuclear Propulsion

NASA Technical Reports Server (NTRS)

Koroteev, Anatoly S.; Ponomarev-Stepnoi, Nicolai N.; Smetannikov, Vladimir P.; Gafarov, Albert A.; Houts, Mike; VanDyke, Melissa; Godfroy, Tom; Martin, James; Bragg-Sitton, Shannon; Dickens, Ricky

2003-01-01

Fission technology can enable rapid, affordable access to any point in the solar system. If fission propulsion systems are to be developed to their full potential; however, near-term customers must be identified and initial fission systems successfully developed, launched, and utilized. Successful utilization will simultaneously develop the infrastructure and experience necessary for developing even higher power and performance systems. To be successful, development programs must devise strategies for rapidly converting paper reactor concepts into actual flight hardware. One approach to accomplishing this is to design highly testable systems, and to structure the program to contain frequent, significant hardware milestones. This paper discusses ongoing efforts in Russia and the United States aimed at enabling near-term utilization of space fission systems.

Preventing Continuous Positive Airway Pressure Failure: Evidence-Based and Physiologically Sound Practices from Delivery Room to the Neonatal Intensive Care Unit.

PubMed

Wright, Clyde J; Sherlock, Laurie G; Sahni, Rakesh; Polin, Richard A

2018-06-01

Routine use of continuous positive airway pressure (CPAP) to support preterm infants with respiratory distress is an evidenced-based strategy to decrease incidence of bronchopulmonary dysplasia. However, rates of CPAP failure remain unacceptably high in very premature neonates, who are at high risk for developing bronchopulmonary dysplasia. Using the GRADE framework to assess the quality of available evidence, this article reviews strategies aimed at decreasing CPAP failure, starting with delivery room interventions and followed through to system-based efforts in the neonatal intensive care unit. Despite best efforts, some very premature neonates fail CPAP. Also reviewed are predictors of CPAP failure in this vulnerable population. Copyright © 2018 Elsevier Inc. All rights reserved.

Technical, analytical and computer support

NASA Technical Reports Server (NTRS)

1972-01-01

The development of a rigorous mathematical model for the design and performance analysis of cylindrical silicon-germanium thermoelectric generators is reported that consists of two parts, a steady-state (static) and a transient (dynamic) part. The material study task involves the definition and implementation of a material study that aims to experimentally characterize the long term behavior of the thermoelectric properties of silicon-germanium alloys as a function of temperature. Analytical and experimental efforts are aimed at the determination of the sublimation characteristics of silicon germanium alloys and the study of sublimation effects on RTG performance. Studies are also performed on a variety of specific topics on thermoelectric energy conversion.

Monitoring and evaluation of disaster response efforts undertaken by local health departments: a rapid realist review.

PubMed

Gossip, Kate; Gouda, Hebe; Lee, Yong Yi; Firth, Sonja; Bermejo, Raoul; Zeck, Willibald; Jimenez Soto, Eliana

2017-06-29

Local health departments are often at the forefront of a disaster response, attending to the immediate trauma inflicted by the disaster and also the long term health consequences. As the frequency and severity of disasters are projected to rise, monitoring and evaluation (M&E) efforts are critical to help local health departments consolidate past experiences and improve future response efforts. Local health departments often conduct M&E work post disaster, however, many of these efforts fail to improve response procedures. We undertook a rapid realist review (RRR) to examine why M&E efforts undertaken by local health departments do not always result in improved disaster response efforts. We aimed to complement existing frameworks by focusing on the most basic and pragmatic steps of a M&E cycle targeted towards continuous system improvements. For these purposes, we developed a theoretical framework that draws on the quality improvement literature to 'frame' the steps in the M&E cycle. This framework encompassed a M&E cycle involving three stages (i.e., document and assess, disseminate and implement) that must be sequentially completed to learn from past experiences and improve future disaster response efforts. We used this framework to guide our examination of the literature and to identify any context-mechanism-outcome (CMO) configurations which describe how M&E may be constrained or enabled at each stage of the M&E cycle. This RRR found a number of explanatory CMO configurations that provide valuable insights into some of the considerations that should be made when using M&E to improve future disaster response efforts. Firstly, to support the accurate documentation and assessment of a disaster response, local health departments should consider how they can: establish a culture of learning within health departments; use embedded training methods; or facilitate external partnerships. Secondly, to enhance the widespread dissemination of lessons learned and facilitate inter-agency learning, evaluation reports should use standardised formats and terminology. Lastly, to increase commitment to improvement processes, local health department leaders should possess positive leadership attributes and encourage shared decision making. This study is among the first to conduct a synthesis of the CMO configurations which facilitate or hinder M&E efforts aimed at improving future disaster responses. It makes a significant contribution to the disaster literature and provides an evidence base that can be used to provide pragmatic guidance for improving M&E efforts of local health departments. PROSPERO 2015: CRD42015023526 .

Advanced Technology Development for Stirling Convertors

NASA Technical Reports Server (NTRS)

Thieme, Lanny G.; Schreiber, Jeffrey G.

2004-01-01

A high-efficiency Stirling Radioisotope Generator (SRG) for use on potential NASA Space Science missions is being developed by the Department of Energy, Lockheed Martin, Stirling Technology Company, and NASA Glenn Research Center (GRC). These missions may include providing spacecraft onboard electric power for deep space missions or power for unmanned Mars rovers. GRC is also developing advanced technology for Stirling convertors, aimed at substantially improving the specific power and efficiency of the convertor and the overall power system. Performance and mass improvement goals have been established for second- and thirdgeneration Stirling radioisotope power systems. Multiple efforts are underway to achieve these goals, both in-house at GRC and under various grants and contracts. The status and results to date for these efforts will be discussed in this paper. Cleveland State University (CSU) is developing a multi-dimensional Stirling computational fluid dynamics code, capable of modeling complete convertors. A 2-D version of the code is now operational, and validation efforts at both CSU and the University of Minnesota are complementing the code development. A screening of advanced superalloy, refractory metal alloy, and ceramic materials has been completed, and materials have been selected for creep and joining characterization as part of developing a high-temperature heater head. A breadboard characterization is underway for an advanced controller using power electronics for active power factor control with a goal of eliminating the heavy tuning capacitors that are typically needed to achieve near unity power factors. Key Stirling developments just initiated under recent NRA (NASA Research Announcement) awards will also be discussed. These include a lightweight convertor to be developed by Sunpower Inc. and an advanced microfabricated regenerator to be done by CSU.

RELAP-7 Code Assessment Plan and Requirement Traceability Matrix

DOE Office of Scientific and Technical Information (OSTI.GOV)

Yoo, Junsoo; Choi, Yong-joon; Smith, Curtis L.

2016-10-01

The RELAP-7, a safety analysis code for nuclear reactor system, is under development at Idaho National Laboratory (INL). Overall, the code development is directed towards leveraging the advancements in computer science technology, numerical solution methods and physical models over the last decades. Recently, INL has also been putting an effort to establish the code assessment plan, which aims to ensure an improved final product quality through the RELAP-7 development process. The ultimate goal of this plan is to propose a suitable way to systematically assess the wide range of software requirements for RELAP-7, including the software design, user interface, andmore » technical requirements, etc. To this end, we first survey the literature (i.e., international/domestic reports, research articles) addressing the desirable features generally required for advanced nuclear system safety analysis codes. In addition, the V&V (verification and validation) efforts as well as the legacy issues of several recently-developed codes (e.g., RELAP5-3D, TRACE V5.0) are investigated. Lastly, this paper outlines the Requirement Traceability Matrix (RTM) for RELAP-7 which can be used to systematically evaluate and identify the code development process and its present capability.« less

U.S. DOE Progress Towards Developing Low-Cost, High Performance, Durable Polymer Electrolyte Membranes for Fuel Cell Applications.

PubMed

Houchins, Cassidy; Kleen, Greg J; Spendelow, Jacob S; Kopasz, John; Peterson, David; Garland, Nancy L; Ho, Donna Lee; Marcinkoski, Jason; Martin, Kathi Epping; Tyler, Reginald; Papageorgopoulos, Dimitrios C

2012-12-18

Low cost, durable, and selective membranes with high ionic conductivity are a priority need for wide-spread adoption of polymer electrolyte membrane fuel cells (PEMFCs) and direct methanol fuel cells (DMFCs). Electrolyte membranes are a major cost component of PEMFC stacks at low production volumes. PEMFC membranes also impose limitations on fuel cell system operating conditions that add system complexity and cost. Reactant gas and fuel permeation through the membrane leads to decreased fuel cell performance, loss of efficiency, and reduced durability in both PEMFCs and DMFCs. To address these challenges, the U.S. Department of Energy (DOE) Fuel Cell Technologies Program, in the Office of Energy Efficiency and Renewable Energy, supports research and development aimed at improving ion exchange membranes for fuel cells. For PEMFCs, efforts are primarily focused on developing materials for higher temperature operation (up to 120 °C) in automotive applications. For DMFCs, efforts are focused on developing membranes with reduced methanol permeability. In this paper, the recently revised DOE membrane targets, strategies, and highlights of DOE-funded projects to develop new, inexpensive membranes that have good performance in hot and dry conditions (PEMFC) and that reduce methanol crossover (DMFC) will be discussed.

Enhancing retention of occupational therapists working in mental health: relationships between wellbeing at work and turnover intention.

PubMed

Scanlan, Justin Newton; Meredith, Pamela; Poulsen, Anne A

2013-12-01

Occupational therapists working in mental health who experience burnout, low work engagement or poor job satisfaction are at risk of poor wellbeing at work and may be more likely to leave their jobs. The aim of this project was to explore factors associated with wellbeing at work and turnover intention in a sample of occupational therapists working in mental health. One hundred and three occupational therapists working in mental health in Queensland completed a survey exploring work/life balance, effort invested in work, rewards received from work, wellbeing at work (job satisfaction, burnout and work engagement) and turnover intention. Analyses were conducted to explore relationships between work/life balance, effort, reward, wellbeing at work and turnover intention. All measures of wellbeing at work were significantly associated with turnover intention. A large proportion (33%) of the variance in turnover intention was predicted by job satisfaction. Perceptions of both work/life balance and effort invested in work, as well as perceived rewards in terms of recognition, prestige and personal satisfaction were significantly associated with work-related wellbeing scores. Results from this study deepen the understanding of factors associated with wellbeing at work and turnover intention for occupational therapists in mental health. This knowledge will support the development of interventions aimed at reducing turnover intention and enhancing retention of occupational therapists in the mental health workforce. © 2013 Occupational Therapy Australia.

Enhancing the contribution of research to health care policy-making: a case study of the Dutch Health Care Performance Report.

PubMed

Hegger, Ingrid; Marks, Lisanne K; Janssen, Susan W J; Schuit, Albertine J; van Oers, Hans A M

2016-01-01

The Dutch Health Care Performance Report, issued by the National Institute of Public Health and the Environment, aims to monitor health care performance in The Netherlands. Both the National Institute and the Ministry of Health wish to increase the contribution of the Report to health care policy-making. Our aim was to identify ways to achieve that. We used contribution mapping as a theoretical framework that recognizes alignment of research as crucial to managing contributions to policy-making. To investigate which areas need alignment efforts by researchers and/or policy-makers, we interviewed National Institute researchers and policy-makers from the Ministry of Health and assessed the process for developing the 2010 Report. We identified six areas where alignment is specifically relevant for enhancing the contributions of future versions of the Dutch Health Care Performance Report: well-balanced information for different ministerial directorates; backstage work; double role actors; reports of other knowledge institutes; data collection/generation and presentation forms. The contribution of health care performance reporting to policy-making is complex and requires continuous alignment efforts between researchers and policy-makers. These efforts should form an inseparable part of health care performance reporting and although this demands considerable resources, it is worth considering since it may pay back in better contributions to policy-making. © The Author(s) 2015.

Formative research and strategic development of a physical activity component to a social marketing campaign for obesity prevention in preschoolers.

PubMed

Bellows, Laura; Anderson, Jennifer; Gould, Susan Martin; Auld, Garry

2008-06-01

The prevalence of overweight in childhood, including preschoolers, continues to rise. While efforts focusing on school-aged children are encouraging, obesity prevention programs to address nutrition and physical activity in the child care center are lacking. Food Friends is a successfully evaluated nutrition program aimed at enhancing preschoolers' food choices, the addition of a physical activity program would improve the programs overall efforts to establish healthful habits early in life. This study describes the formative research conducted with secondary influencers of preschoolers-teachers and parents-for the development of a physical activity program. Key informant interviews and focus group discussions were conducted with preschool teachers and parents, respectively, to examine current physical activity practices, as well as attitudes, opinions, and desired wants and needs for physical activity materials. Findings illustrate that teachers provided physical activity; however, most did not use a structured program. Teachers identified time, space and equipment as barriers to providing activity in their classroom. Focus group findings identified activities of preschoolers', parents' perceptions of the adequacy of activity levels, and items to help parents engage their children in more physical activity. Barriers were also identified by parents and included time, safety, inclement weather, and lack of knowledge and self-efficacy. Findings from this formative research were used to develop a marketing strategy to guide the development of a physical activity component, Food Friends Get Movin' with Mighty Moves , as part of a larger social marketing campaign aimed to decrease the risk for obesity in low-income preschoolers.

No Equity, No Triple Aim: Strategic Proposals to Advance Health Equity in a Volatile Policy Environment

PubMed Central

Sager, Alan; Selig, Sara; Antonelli, Richard; Morton, Samantha; Hirsch, Gail; Lee, Celeste Reid; Ortiz, Abigail; Fox, Durrell; Lupi, Monica Valdes; Acuff, Cecilia; Wachman, Madeline

2017-01-01

Health professionals, including social workers, community health workers, public health workers, and licensed health care providers, share common interests and responsibilities in promoting health equity and improving social determinants of health—the conditions in which people live, work, play, and learn. We summarize the underlying causes of health inequity and comparatively poor health outcomes in the United States. We describe barriers to realizing the hope embedded in the 2010 Patient Protection and Affordable Care Act, that moving away from fee-for-service payments will naturally drive care upstream as providers respond to greater financial risk by undertaking greater prevention efforts for the health of their patients. We assert that health equity should serve as the guiding framework for achieving the Triple Aim of health care reform and outline practical opportunities for improving care and promoting stronger efforts to address social determinants of health. These proposals include developing a dashboard of measures to assist providers committed to health equity and community-based prevention and to promote institutional accountability for addressing socioeconomic factors that influence health. PMID:29236539

"The Delinquents": Censorship and Youth Culture in Recent U.S. History.

ERIC Educational Resources Information Center

Cohen, Ronald D.

1997-01-01

Describes the efforts of authorities to respond to the burgeoning youth culture of the 1950s. Details the censorship efforts aimed at those aspects of youth culture (comic books, rock and roll) that were viewed as dangerous and subversive. Identifies these effort within the corresponding social, political, and cultural climate. (MJP)

Trust and Extra Effort Implementing Curriculum Reform: The Mediating Effects of Collaboration

ERIC Educational Resources Information Center

Cerit, Yusuf

2013-01-01

This study aims to examine the relationship between trust and extra effort implementing reform, and relationship between trust and extra effort are mediated by collaboration. The study was carried out in elementary schools in Turkey. Faculty trust in schools was measured using the Omnibus T-Scale, collaboration was measured using collaboration…

Hard facts about soft skills.

PubMed

Ray, Joel D; Overman, Angela S

2014-02-01

This is the third article in a series on leadership coordinated by the American Organization of Nurse Executives (AONE) that highlights how nurses are leading change efforts in hospitals. It describes work done in conjunction with the AONE's Care Innovation and Transformation initiative, which provides leadership development and educational opportunities to nurse managers and staff aimed at supporting nurses at the point of care in making changes to improve the quality and safety of patient care.

Improving National Capacity to Respond to Complex Emergencies, The U.S. Experience

DTIC Science & Technology

1998-04-01

effort. As one who was responsible for operations in Africa , Europe, and the Middle East, I can attest to the lack of a systematic process for de...social, and economic. 7 Humanitarian assistance aims to meet the basic subsistence needs of the population: food, water , shelter, and health care...organization could specialize in reforming civilian police, while another develops a capability for water purification. Specifying roles can lead to

Climatic factors related to land-use planning in the Puget Sound basin, Washington

USGS Publications Warehouse

Foxworthy, B.L.; Richardson, Donald

1973-01-01

The purpose of this study is to review available data related to the climate of the Puget Sound basin and to present selected climatic information along with an evaluation of its significance and general adequacy for planning purposes. This is part of continuing efforts aimed at imporving the accessibility and usefulness of environmental and other data needed for land-use planning, resource development, and environmental protection. 

From good intentions to healthy habits: towards integrated computational models of goal striving and habit formation.

PubMed

Pirolli, Peter

2016-08-01

Computational models were developed in the ACT-R neurocognitive architecture to address some aspects of the dynamics of behavior change. The simulations aim to address the day-to-day goal achievement data available from mobile health systems. The models refine current psychological theories of self-efficacy, intended effort, and habit formation, and provide an account for the mechanisms by which goal personalization, implementation intentions, and remindings work.

Alkaline static feed electrolyzer based oxygen generation system

NASA Technical Reports Server (NTRS)

Noble, L. D.; Kovach, A. J.; Fortunato, F. A.; Schubert, F. H.; Grigger, D. J.

1988-01-01

In preparation for the future deployment of the Space Station, an R and D program was established to demonstrate integrated operation of an alkaline Water Electrolysis System and a fuel cell as an energy storage device. The program's scope was revised when the Space Station Control Board changed the energy storage baseline for the Space Station. The new scope was aimed at the development of an alkaline Static Feed Electrolyzer for use in an Environmental Control/Life Support System as an oxygen generation system. As a result, the program was divided into two phases. The phase 1 effort was directed at the development of the Static Feed Electrolyzer for application in a Regenerative Fuel Cell System. During this phase, the program emphasized incorporation of the Regenerative Fuel Cell System design requirements into the Static Feed Electrolyzer electrochemical module design and the mechanical components design. The mechanical components included a Pressure Control Assembly, a Water Supply Assembly and a Thermal Control Assembly. These designs were completed through manufacturing drawing during Phase 1. The Phase 2 effort was directed at advancing the Alkaline Static Feed Electrolyzer database for an oxygen generation system. This development was aimed at extending the Static Feed Electrolyzer database in areas which may be encountered from initial fabrication through transportation, storage, launch and eventual Space Station startup. During this Phase, the Program emphasized three major areas: materials evaluation, electrochemical module scaling and performance repeatability and Static Feed Electrolyzer operational definition and characterization.

Recruitment of multiple stakeholders to health services research: lessons from the front lines.

PubMed

Kho, Michelle E; Rawski, Ellen; Makarski, Julie; Brouwers, Melissa C

2010-05-13

Self-administered surveys are an essential methodological tool for health services and knowledge translation research, and engaging end-users of the research is critical. However, few documented accounts of the efforts invested in recruitment of multiple different stakeholders to one health services research study exist. Here, we highlight the challenges of recruiting key stakeholders (policy-makers, clinicians, guideline developers) to a Canadian Institutes of Health Research (CIHR) funded health services research (HSR) study aimed to develop an updated and refined version of a guideline appraisal tool, the AGREE. Using evidence-based methods of recruitment, our goal was to recruit 192 individuals: 80 international guideline developers, 80 Canadian clinicians and 32 Canadian policy/decision-makers. We calculated the participation rate and the recruitment efficiency. We mailed 873 invitation letters. Of 838 approached, our participation rate was 29%(240) and recruitment efficiency, 19%(156). One policy-maker manager did not allow policy staff to participate in the study. Based on the results from this study, we suggest that future studies aiming to engage similar stakeholders in HSR over sample by at least 5 times to achieve their target sample size and allow for participant withdrawals. We need continued efforts to communicate the value of research between researchers and end-users of research (policy-makers, clinicians, and other researchers), integration of participatory research strategies, and promotion of the value of end-user involvement in research. Future research to understand methods of improving recruitment efficiency and engaging key stakeholders in HSR is warranted.

Associations between occupational stress, burnout and well-being among manufacturing workers: mediating roles of psychological capital and self-esteem.

PubMed

Wang, Ziyue; Liu, Hongbo; Yu, Haijian; Wu, Yanwen; Chang, Shuai; Wang, Lie

2017-11-15

Occupational stress is an important risk factor for mental health among occupational population. Exploring related mediators of workers' mental health are important to improve their health and performance. Our study aims to explore the relationships between work stress, positive psychological resources, burnout and well-being. The study was performed during the period of June and July in 2015. A questionnaire that consisted of the Effort-reward Imbalance Scale, the Maslach Burnout Inventory-General Survey, the Psychological Capital Questionnaire, the Rosenberg Self-esteem Scale, the Flourishing Scale, as well as demographic and working factors. Psychological capital mediated the associations of effort-reward imbalance and emotional exhaustion, cynicism, professional efficacy and well-being. Self-esteem mediated the associations of effort-reward imbalance ratio with cynicism, professional efficacy and well-being, and mediated the associations of overcommitment and cynicism, professional efficacy and well-being. The findings indicated that enhancing positive psychological resources could be considered in developing intervention strategies for psychological health among manufacturing employees.

Roles for specialty societies and vascular surgeons in accountable care organizations

PubMed Central

Goodney, Philip P.; Fisher, Elliott S.; Cambria, Richard P.

2012-01-01

With the passage of the Affordable Care Act, accountable care organizations (ACOs) represent a new paradigm in healthcare payment reform. Designed to limit growth in spending while preserving quality, these organizations aim to incant physicians to lower costs by returning a portion of the savings realized by cost-effective, evidence-based care back to the ACO. In this review, first, we will explore the development of ACOs within the context of prior attempts to control Medicare spending, such as the sustainable growth rate and managed care organizations. Second, we describe the evolution of ACOs, the demonstration projects that established their feasibility, and their current organizational structure. Third, because quality metrics are central to the use and implementation of ACOs, we describe current efforts to design, collect, and interpret quality metrics in vascular surgery. And fourth, because a “seat at the table” will be an important key to success for vascular surgeons in these efforts, we discuss how vascular surgeons can participate and lead efforts within ACOs. PMID:22370029

A Review of Research on Impulsive Loading of Marine Composites

NASA Astrophysics Data System (ADS)

Porfiri, Maurizio; Gupta, Nikhil

Impulsive loading conditions, such as those produced by blast waves, are being increasingly recognized as relevant in marine applications. Significant research efforts are directed towards understanding the impulsive loading response of traditional naval materials, such as aluminum and steel, and advanced composites, such as laminates and sandwich structures. Several analytical studies are directed towards establishing predictive models for structural response and failure of marine structures under blast loading. In addition, experimental research efforts are focused on characterizing structural response to blast loading. The aim of this review is to provide a general overview of the state of the art on analytical and experimental studies in this field that can serve as a guideline for future research directions. Reported studies cover the Office of Naval Research-Solid Mechanics Program sponsored research along with other worldwide research efforts of relevance to marine applications. These studies have contributed to developing a fundamental knowledge of the mechanics of advanced materials subjected to impulsive loading, which is of interest to all Department of Defense branches.

A unique degree program for pre-pharmacy education: An undergraduate degree in pharmaceutical sciences.

PubMed

Jafari, Mahtab

2018-02-01

Within the coming decade, the demand for well-trained pharmacists is expected to only increase, especially with the aging of the United States (US) population. To help fill this growing demand, the University of California, Irvine (UCI) aims to offer a unique pre-pharmacy degree program and has developed a Bachelor of Science (BS) degree in Pharmaceutical Sciences to help achieve this goal. In this commentary, we share our experience with our curriculum and highlight its features in an effort to encourage other institutions to enhance the learning experience of their pre-pharmacy students. The efforts of the UCI Department of Pharmaceutical Sciences has resulted in UCI being consistently ranked as one of the top feeder institutions by the Pharmacy College Application Service (PharmCAS) in recent years. The UCI Pharmaceutical Sciences Bachelor of Science offers a unique pre-pharmacy educational experience in an effort to better prepare undergraduates for the rigors of the doctorate of pharmacy curriculum. Copyright © 2017. Published by Elsevier Inc.

NASA Work Breakdown Structure (WBS) Handbook

NASA Technical Reports Server (NTRS)

Terrell, Stefanie M.

2018-01-01

The purpose of this document is to provide program/project teams necessary instruction and guidance in the best practices for Work Breakdown Structure (WBS) and WBS dictionary development and use for project implementation and management control. This handbook can be used for all types of NASA projects and work activities including research, development, construction, test and evaluation, and operations. The products of these work efforts may be hardware, software, data, or service elements (alone or in combination). The aim of this document is to assist project teams in the development of effective work breakdown structures that provide a framework of common reference for all project elements.

State of the Art Assessment of Simulation in Advanced Materials Development

NASA Technical Reports Server (NTRS)

Wise, Kristopher E.

2008-01-01

Advances in both the underlying theory and in the practical implementation of molecular modeling techniques have increased their value in the advanced materials development process. The objective is to accelerate the maturation of emerging materials by tightly integrating modeling with the other critical processes: synthesis, processing, and characterization. The aims of this report are to summarize the state of the art of existing modeling tools and to highlight a number of areas in which additional development is required. In an effort to maintain focus and limit length, this survey is restricted to classical simulation techniques including molecular dynamics and Monte Carlo simulations.

Application of improved technology to a preprototype vapor compression distillation /VCD/ water recovery subsystem

NASA Technical Reports Server (NTRS)

Johnson, K. L.; Reysa, R. P.; Fricks, D. H.

1981-01-01

Vapor compression distillation (VCD) is considered the most efficient water recovery process for spacecraft application. This paper reports on a preprototype VCD which has undergone the most extensive operational and component development testing of any VCD subsystem to date. The component development effort was primarily aimed at eliminating corrosion and the need for lubrication, upgrading electronics, and substituting nonmetallics in key rotating components. The VCD evolution is documented by test results on specific design and/or materials changes. Innovations worthy of further investigation and additional testing are summarized for future VCD subsystem development reference. Conclusions on experience gained are presented.

Evolution of Autonomous Self-Righting Behaviors for Articulated Nanorovers

NASA Technical Reports Server (NTRS)

Tunstel, Edward

1999-01-01

Miniature rovers with articulated mobility mechanisms are being developed for planetary surface exploration on Mars and small solar system bodies. These vehicles are designed to be capable of autonomous recovery from overturning during surface operations. This paper describes a computational means of developing motion behaviors that achieve the autonomous recovery function. It proposes a control software design approach aimed at reducing the effort involved in developing self-righting behaviors. The approach is based on the integration of evolutionary computing with a dynamics simulation environment for evolving and evaluating motion behaviors. The automated behavior design approach is outlined and its underlying genetic programming infrastructure is described.

Rural migration: The driving force behind tropical deforestation on the settlement frontier

PubMed Central

Carr, David

2009-01-01

This paper reviews the state of knowledge and develops a conceptual model for researching frontier migration in the developing world with a focus on Latin America. Since only a small fraction of migrants move to forest frontiers, identifying people and place characteristics associated with this phenomenon could usefully inform policies aimed at forest conservation and rural development. Yet population scholars train their efforts on urban and international migration while land use/cover change researchers pay scant attention to these migration flows which directly antecede the most salient footprint of human occupation on the earth's surface: the conversion of forest to agricultural land. PMID:20485541

Monitoring osseointegration and developing intelligent systems (Conference Presentation)

NASA Astrophysics Data System (ADS)

Salvino, Liming W.

2017-05-01

Effective monitoring of structural and biological systems is an extremely important research area that enables technology development for future intelligent devices, platforms, and systems. This presentation provides an overview of research efforts funded by the Office of Naval Research (ONR) to establish structural health monitoring (SHM) methodologies in the human domain. Basic science efforts are needed to utilize SHM sensing, data analysis, modeling, and algorithms to obtain the relevant physiological and biological information for human-specific health and performance conditions. This overview of current research efforts is based on the Monitoring Osseointegrated Prosthesis (MOIP) program. MOIP develops implantable and intelligent prosthetics that are directly anchored to the bone of residual limbs. Through real-time monitoring, sensing, and responding to osseointegration of bones and implants as well as interface conditions and environment, our research program aims to obtain individualized actionable information for implant failure identification, load estimation, infection mitigation and treatment, as well as healing assessment. Looking ahead to achieve ultimate goals of SHM, we seek to expand our research areas to cover monitoring human, biological and engineered systems, as well as human-machine interfaces. Examples of such include 1) brainwave monitoring and neurological control, 2) detecting and evaluating brain injuries, 3) monitoring and maximizing human-technological object teaming, and 4) closed-loop setups in which actions can be triggered automatically based on sensors, actuators, and data signatures. Finally, some ongoing and future collaborations across different disciplines for the development of knowledge automation and intelligent systems will be discussed.

Enabling Data Access for Environmental Monitoring: SERVIR West Africa

NASA Astrophysics Data System (ADS)

Yetman, G.; de Sherbinin, A. M.

2017-12-01

SERVIR is a join effort between NASA and the U.S. Agency for International Development to form regional partnerships and bring satellite-based earth monitoring and geographic information technologies to bear on environmental issues. The recently established SERVIR node for West Africa aims to "connect space to villages" and enable response to environmental change at the national and local level through partnering with a network of organizations in the region. Comprehensive services—data streams, analysis methods and algorithms, and information products for decision making—to support environmental monitoring of five critical issues identified by West African network members are being designed and developed: ephemeral water, charcoal production, locusts, groundwater, and land use/land cover change. Additionally, climate change information is critical for planning and context in each of these issues. The selection of data and methods is a collaborative effort, with experts in the region working with experts at NASA and the scientific community to best meet information monitoring requirements. Design and delivery of these services requires capacity development in a number of areas, including best practices in data management, analysis methods for combining multiple data streams, and information technology infrastructure. Two research centers at Columbia University are implementing partners for SERVIR West Africa, acting to support capacity development in network members through a combination of workshops, training, and implementation of technologies in the region. The presentation will focus on efforts by these centers to assess current capabilities and improve capacity through gathering requirements, system design, technology selection, technology deployment, training, and workshops.

A CMMI-based approach for medical software project life cycle study.

PubMed

Chen, Jui-Jen; Su, Wu-Chen; Wang, Pei-Wen; Yen, Hung-Chi

2013-01-01

In terms of medical techniques, Taiwan has gained international recognition in recent years. However, the medical information system industry in Taiwan is still at a developing stage compared with the software industries in other nations. In addition, systematic development processes are indispensable elements of software development. They can help developers increase their productivity and efficiency and also avoid unnecessary risks arising during the development process. Thus, this paper presents an application of Light-Weight Capability Maturity Model Integration (LW-CMMI) to Chang Gung Medical Research Project (CMRP) in the Nuclear medicine field. This application was intended to integrate user requirements, system design and testing of software development processes into three layers (Domain, Concept and Instance) model. Then, expressing in structural System Modeling Language (SysML) diagrams and converts part of the manual effort necessary for project management maintenance into computational effort, for example: (semi-) automatic delivery of traceability management. In this application, it supports establishing artifacts of "requirement specification document", "project execution plan document", "system design document" and "system test document", and can deliver a prototype of lightweight project management tool on the Nuclear Medicine software project. The results of this application can be a reference for other medical institutions in developing medical information systems and support of project management to achieve the aim of patient safety.

2005 NASA Seal/Secondary Air System Workshop, Volume 1

NASA Technical Reports Server (NTRS)

Steinetz, Bruce M. (Editor); Hendricks, Robert C. (Editor)

2006-01-01

The 2005 NASA Seal/Secondary Air System workshop covered the following topics: (i) Overview of NASA s new Exploration Initiative program aimed at exploring the Moon, Mars, and beyond; (ii) Overview of the NASA-sponsored Propulsion 21 Project; (iii) Overview of NASA Glenn s seal project aimed at developing advanced seals for NASA s turbomachinery, space, and reentry vehicle needs; (iv) Reviews of NASA prime contractor, vendor, and university advanced sealing concepts including tip clearance control, test results, experimental facilities, and numerical predictions; and (v) Reviews of material development programs relevant to advanced seals development. Turbine engine studies have shown that reducing high-pressure turbine (HPT) blade tip clearances will reduce fuel burn, lower emissions, retain exhaust gas temperature margin, and increase range. Several organizations presented development efforts aimed at developing faster clearance control systems and associated technology to meet future engine needs. The workshop also covered several programs NASA is funding to develop technologies for the Exploration Initiative and advanced reusable space vehicle technologies. NASA plans on developing an advanced docking and berthing system that would permit any vehicle to dock to any on-orbit station or vehicle. Seal technical challenges (including space environments, temperature variation, and seal-on-seal operation) as well as plans to develop the necessary "androgynous" seal technologies were reviewed. Researchers also reviewed tests completed for the shuttle main landing gear door seals.

Automated Work Package: Conceptual Design and Data Architecture

DOE Office of Scientific and Technical Information (OSTI.GOV)

Al Rashdan, Ahmad; Oxstrand, Johanna; Agarwal, Vivek

The automated work package (AWP) is one of the U.S. Department of Energy’s (DOE) Light Water Reactor Sustainability Program efforts to enhance the safety and economics of the nuclear power industry. An AWP is an adaptive and interactive work package that intelligently drives the work process according to the plant condition, resources status, and users progress. The AWP aims to automate several manual tasks of the work process to enhance human performance and reduce human errors. Electronic work packages (eWPs), studied by the Electric Power Research Institute (EPRI), are work packages that rely to various extent on electronic data processingmore » and presentation. AWPs are the future of eWPs. They are envisioned to incorporate the advanced technologies of the future, and thus address the unresolved deficiencies associated with the eWPs in a nuclear power plant. In order to define the AWP, it is necessary to develop an ideal envisioned scenario of the future work process without any current technology restriction. The approach followed to develop this scenario is specific to every stage of the work process execution. The scenario development resulted in fifty advanced functionalities that can be part of the AWP. To rank the importance of these functionalities, a survey was conducted involving several U.S. nuclear utilities. The survey aimed at determining the current need of the nuclear industry with respect to the current work process, i.e. what the industry is satisfied with, and where the industry envisions potential for improvement. The survey evaluated the most promising functionalities resulting from the scenario development. The results demonstrated a significant desire to adopt the majority of these functionalities. The results of the survey are expected to drive the Idaho National Laboratory (INL) AWP research and development (R&D). In order to facilitate this mission, a prototype AWP is needed. Since the vast majority of earlier efforts focused on the frontend aspects of the AWP, the backend data architecture was researched and developed in this effort. The backend design involved data architecture aspects. It was realized through this effort that the key aspects of this design are hierarchy, data configuration and live information, data templates and instances, the flow of work package execution, the introduction of properties, and the means to interface the backend to the frontend. After the backend design was developed, a data structure was built to reflect the developed data architecture. The data structure was developed to accommodate the fifty functionalities identified by the envisioned scenario development. The data structure was evaluated by incorporating an example work order from the nuclear power industry. The implementation resulted in several optimization iterations of the data structure. In addition, the rearrangement of the work order information to fit the data structure highlighted several possibilities for improvement in the current work order design, and significantly reduced the size of the work order.« less

Developing tools for digital radar image data evaluation

NASA Technical Reports Server (NTRS)

Domik, G.; Leberl, F.; Raggam, J.

1986-01-01

The refinement of radar image analysis methods has led to a need for a systems approach to radar image processing software. Developments stimulated through satellite radar are combined with standard image processing techniques to create a user environment to manipulate and analyze airborne and satellite radar images. One aim is to create radar products for the user from the original data to enhance the ease of understanding the contents. The results are called secondary image products and derive from the original digital images. Another aim is to support interactive SAR image analysis. Software methods permit use of a digital height model to create ortho images, synthetic images, stereo-ortho images, radar maps or color combinations of different component products. Efforts are ongoing to integrate individual tools into a combined hardware/software environment for interactive radar image analysis.

Educational Effectiveness, Target, and Content for Prudent Antibiotic Use

PubMed Central

Lee, Chang-Ro; Lee, Jung Hun; Kang, Lin-Woo; Jeong, Byeong Chul; Lee, Sang Hee

2015-01-01

Widespread antimicrobial use and concomitant resistance have led to a significant threat to public health. Because inappropriate use and overuse of antibiotics based on insufficient knowledge are one of the major drivers of antibiotic resistance, education about prudent antibiotic use aimed at both the prescribers and the public is important. This review investigates recent studies on the effect of interventions for promoting prudent antibiotics prescribing. Up to now, most educational efforts have been targeted to medical professionals, and many studies showed that these educational efforts are significantly effective in reducing antibiotic prescribing. Recently, the development of educational programs to reduce antibiotic use is expanding into other groups, such as the adult public and children. The investigation of the contents of educational programs for prescribers and the public demonstrates that it is important to develop effective educational programs suitable for each group. In particular, it seems now to be crucial to develop appropriate curricula for teaching medical and nonmedical (pharmacy, dentistry, nursing, veterinary medicine, and midwifery) undergraduate students about general medicine, microbial virulence, mechanism of antibiotic resistance, and judicious antibiotic prescribing. PMID:25945327

NASA developments in solid state power amplifiers

NASA Technical Reports Server (NTRS)

Leonard, Regis F.

1990-01-01

Over the last ten years, NASA has undertaken an extensive program aimed at development of solid state power amplifiers for space applications. Historically, the program may be divided into three phases. The first efforts were carried out in support of the advanced communications technology satellite (ACTS) program, which is developing an experimental version of a Ka-band commercial communications system. These first amplifiers attempted to use hybrid technology. The second phase was still targeted at ACTS frequencies, but concentrated on monolithic implementations, while the current, third phase, is a monolithic effort that focusses on frequencies appropriate for other NASA programs and stresses amplifier efficiency. The topics covered include: (1) 20 GHz hybrid amplifiers; (2) 20 GHz monolithic MESFET power amplifiers; (3) Texas Instruments' (TI) 20 GHz variable power amplifier; (4) TI 20 GHz high power amplifier; (5) high efficiency monolithic power amplifiers; (6) GHz high efficiency variable power amplifier; (7) TI 32 GHz monolithic power amplifier performance; (8) design goals for Hughes' 32 GHz variable power amplifier; and (9) performance goals for Hughes' pseudomorphic 60 GHz power amplifier.

Detection, discrimination, and real-time tracking of cracks in rotating disks

NASA Astrophysics Data System (ADS)

Haase, Wayne C.; Drumm, Michael J.

2002-06-01

The purpose of this effort was to develop a system* to detect, discriminate and track fatigue cracks in rotating disks. Aimed primarily at jet engines in flight applications, the system also has value for detecting cracks in a spin pit during low cycle fatigue testing, and for monitoring the health of steam turbines and land-based gas turbine engines for maintenance purposes. The results of this effort produced: a physics-based model that describes the change in the center of mass of a rotating disk using damping ratio, initial unbalance and crack size as parameters; the development of a data acquisition and analysis system that can detect and discriminate a crack using a single cycle of data; and initial validation of the model through testing in a spin pit. The development of the physics-based model also pointed to the most likely regimes for crack detection; identified specific powers of (omega) search for in specific regimes; dictated a particular type of data acquisition for crack discrimination; and demonstrated a need for a higher signal-to-noise ratio in the measurement of the basic vibration signal.

Precision Casting via Advanced Simulation and Manufacturing

NASA Technical Reports Server (NTRS)

1997-01-01

A two-year program was conducted to develop and commercially implement selected casting manufacturing technologies to enable significant reductions in the costs of castings, increase the complexity and dimensional accuracy of castings, and reduce the development times for delivery of high quality castings. The industry-led R&D project was cost shared with NASA's Aerospace Industry Technology Program (AITP). The Rocketdyne Division of Boeing North American, Inc. served as the team lead with participation from Lockheed Martin, Ford Motor Company, Howmet Corporation, PCC Airfoils, General Electric, UES, Inc., University of Alabama, Auburn University, Robinson, Inc., Aracor, and NASA-LeRC. The technical effort was organized into four distinct tasks. The accomplishments reported herein. Task 1.0 developed advanced simulation technology for core molding. Ford headed up this task. On this program, a specialized core machine was designed and built. Task 2.0 focused on intelligent process control for precision core molding. Howmet led this effort. The primary focus of these experimental efforts was to characterize the process parameters that have a strong impact on dimensional control issues of injection molded cores during their fabrication. Task 3.0 developed and applied rapid prototyping to produce near net shape castings. Rocketdyne was responsible for this task. CAD files were generated using reverse engineering, rapid prototype patterns were fabricated using SLS and SLA, and castings produced and evaluated. Task 4.0 was aimed at developing technology transfer. Rocketdyne coordinated this task. Casting related technology, explored and evaluated in the first three tasks of this program, was implemented into manufacturing processes.

NASA and Superalloys: A Customer, a Participant, and a Referee

NASA Technical Reports Server (NTRS)

Nathal, Michael V.

2008-01-01

NASA has had a long history of research and development in the field of superalloys. These efforts have continued today, where the latest advancements in turbine disk and blade technologies are being developed Although NASA does support military flight systems, it s predominant role is in supporting civilian air transportation systems, and thus has goals for improving fuel efficiency, emissions, noise, and safety of today s aircraft. NASA has traditionally served several distinct but complimentary roles as participants in multi-disciplinary research teams, as customers who fund research and development efforts at industry and universities, and as referees who can address broad issues that affect the entire aeronautics community. Because of our longer range viewpoint, we can take on higher risk, higher reward research topics. NASA can also serve as an intermediary between the basic research performed primarily at universities and the development efforts emphasized by industry. By interacting with individual companies, NASA can identify areas of general interest and problems common to a large portion of the aeronautics community, and devise programs aimed at solving these problems. In space missions, NASA is a direct customer responsible for developing vehicles. In the case of the Space Shuttle, NASA has worked with various contractors to design and build numerous components out of superalloys. Another fascinating area for the use of superalloys is in power systems for long life applications in space. Potential missions include providing electric power for deep space missions, surface rovers, including lunar and Mars, and stationary power generators on the lunar surface.

Experiences with Text Mining Large Collections of Unstructured Systems Development Artifacts at JPL

NASA Technical Reports Server (NTRS)

Port, Dan; Nikora, Allen; Hihn, Jairus; Huang, LiGuo

2011-01-01

Often repositories of systems engineering artifacts at NASA's Jet Propulsion Laboratory (JPL) are so large and poorly structured that they have outgrown our capability to effectively manually process their contents to extract useful information. Sophisticated text mining methods and tools seem a quick, low-effort approach to automating our limited manual efforts. Our experiences of exploring such methods mainly in three areas including historical risk analysis, defect identification based on requirements analysis, and over-time analysis of system anomalies at JPL, have shown that obtaining useful results requires substantial unanticipated efforts - from preprocessing the data to transforming the output for practical applications. We have not observed any quick 'wins' or realized benefit from short-term effort avoidance through automation in this area. Surprisingly we have realized a number of unexpected long-term benefits from the process of applying text mining to our repositories. This paper elaborates some of these benefits and our important lessons learned from the process of preparing and applying text mining to large unstructured system artifacts at JPL aiming to benefit future TM applications in similar problem domains and also in hope for being extended to broader areas of applications.

Schools, Families, and the Prevention of Child Maltreatment: Lessons That Can Be Learned From a Literature Review.

PubMed

Admon Livny, Karen; Katz, Carmit

2018-04-01

Child maltreatment is a worldwide social problem that receives considerable attention. However, prevention efforts remain rare, allowing the phenomenon to continue and spread. The aim of the current article is to systematically review evidence-based prevention efforts that address schools and families as key stakeholders for preventing child maltreatment. Using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, a thorough literature review revealed that only five programs matched the inclusion criteria for the current article. These programs were analyzed for several domains, including level of prevention, target population, participants, and the programs' outcomes. The current review highlights the urgent needs to develop, modify, and further evaluate prevention programs for child maltreatment in the context of the ecological model. More specifically, it illuminates the need to create and champion programs that enhance the collaboration between families and schools, both of which are key stakeholders within the phenomenon of child maltreatment. Collaboration between policymakers, researchers, and practitioners should guide future efforts by promoting cultural adaptation to such programs and by integrating children's perceptions to improve these efforts and to benefit everyone involved.

Analyzing and Predicting Effort Associated with Finding and Fixing Software Faults

NASA Technical Reports Server (NTRS)

Hamill, Maggie; Goseva-Popstojanova, Katerina

2016-01-01

Context: Software developers spend a significant amount of time fixing faults. However, not many papers have addressed the actual effort needed to fix software faults. Objective: The objective of this paper is twofold: (1) analysis of the effort needed to fix software faults and how it was affected by several factors and (2) prediction of the level of fix implementation effort based on the information provided in software change requests. Method: The work is based on data related to 1200 failures, extracted from the change tracking system of a large NASA mission. The analysis includes descriptive and inferential statistics. Predictions are made using three supervised machine learning algorithms and three sampling techniques aimed at addressing the imbalanced data problem. Results: Our results show that (1) 83% of the total fix implementation effort was associated with only 20% of failures. (2) Both safety critical failures and post-release failures required three times more effort to fix compared to non-critical and pre-release counterparts, respectively. (3) Failures with fixes spread across multiple components or across multiple types of software artifacts required more effort. The spread across artifacts was more costly than spread across components. (4) Surprisingly, some types of faults associated with later life-cycle activities did not require significant effort. (5) The level of fix implementation effort was predicted with 73% overall accuracy using the original, imbalanced data. Using oversampling techniques improved the overall accuracy up to 77%. More importantly, oversampling significantly improved the prediction of the high level effort, from 31% to around 85%. Conclusions: This paper shows the importance of tying software failures to changes made to fix all associated faults, in one or more software components and/or in one or more software artifacts, and the benefit of studying how the spread of faults and other factors affect the fix implementation effort.

Competing Discourses of Academic Spanish in the Texas-Mexico Borderlands

ERIC Educational Resources Information Center

Guerrero, Michael D.; Guerrero, Maria Consuelo

2017-01-01

In this descriptive study the efforts of a faculty to prepare a cohort of pre-service bilingual education teachers to pass a newly adopted state certification test of academic Spanish are presented. The faculty's efforts were aimed at offsetting a low pass rate on this test, but unfortunately efforts fell short. To unpack this outcome, the authors…

Scaling up access to oral rehydration solution for diarrhea: Learning from historical experience in low– and high–performing countries

PubMed Central

Wilson, Shelby E.; Morris, Saul S.; Gilbert, Sarah Skye; Mosites, Emily; Hackleman, Rob; Weum, Kristoffer L.M.; Pintye, Jillian; Manhart, Lisa E.; Hawes, Stephen E.

2013-01-01

Aim This paper aims to identify factors that systematically predict why some countries that have tried to scale up oral rehydration solution (ORS) have succeeded, and others have not. Methods We examined ORS coverage over time, across countries, and through case studies. We conducted expert interviews and literature and data searches to better understand the history of ORS scale–up efforts and why they failed or succeeded in nine countries. We used qualitative, pairwise (or three–country) comparisons of geographically or otherwise similar countries that had different outcomes in terms of ORS scale–up. An algorithm was developed which scored country performance across key supply, demand and financing activities to quantitatively assess the scale–up efforts in each country. Results The vast majority of countries have neither particularly low nor encouragingly high ORS use rates. We observed three clearly identifiable contrasts between countries that achieved and sustained high ORS coverage and those that did not. Key partners across sectors have critical roles to play to effectively address supply– and demand–side barriers. Efforts must synchronize demand generation, private provider outreach and public sector work. Many donor funds are either suspended or redirected in the event of political instability, exacerbating the health challenges faced by countries in these contexts. We found little information on the cost of scale–up efforts. Conclusions We identified a number of characteristics of successful ORS scale–up programs, including involvement of a broad range of key players, addressing supply and demand generation together, and working with both public and private sectors. Dedicated efforts are needed to launch and sustain success, including monitoring and evaluation plans to track program costs and impacts. These case studies were designed to inform programmatic decision–making; thus, rigorous academic methods to qualitatively and quantitatively evaluate country ORS scale–up programs might yield additional, critical insights and confirm our conclusions. PMID:23826508

Aerospace manpower transfer to small business enterprises

NASA Technical Reports Server (NTRS)

Green, M. K.

1972-01-01

The feasibility of a program to effect transfer of aerospace professional people from the ranks of the unemployed into gainful employment in the small business community was investigated. The effectiveness of accomplishing transfer of technology from the aerospace effort into the private sector through migration of people rather than products or hardware alone was also studied. Two basic methodologies were developed. One involves the matching of ex-aerospace professionals and small companies according to their mutual needs. A training and indoctrination program is aimed at familiarizing the professional with the small company environment, and a program of follow-up counseling is defined. The second methodology incorporates efforts to inform and arouse interest among the nonaerospace business community toward affirmative action programs that will serve mutual self-interests of the individuals, companies, and communities involved.

Airway smooth muscle: a potential target for asthma therapy.

PubMed

Dowell, Maria L; Lavoie, Tera L; Solway, Julian; Krishnan, Ramaswamy

2014-01-01

Asthma is a major public health problem that afflicts nearly one in 20 people worldwide. Despite available treatments, asthma symptoms remain poorly controlled in a significant minority of asthma patients, especially those with severe disease. Accordingly, much ongoing effort has been directed at developing new therapeutic strategies; these efforts are described in detail below. Although mucus hypersecretion is an important component of asthma pathobiology, the primary mechanism of morbidity and mortality in asthma is excessive narrowing of the airway. The key end- effector of excessive airway narrowing is airway smooth muscle (ASM) contraction; overcoming ASM contraction is therefore a prominent therapeutic strategy. Here, we review exciting new advances aimed at ASM relaxation. Exciting advances in ASM biology have identified new therapeutic targets for the prevention or reversal of bronchoconstriction in asthma.

On Achieving Transdisciplinary Outcomes from Synergistic Research Efforts in the Northern Gulf of Mexico

NASA Astrophysics Data System (ADS)

Hagen, S. C.

2017-12-01

Multiple federal initiatives aim to evaluate and enhance sustainability and resilience at the coastal-land margin. Progressive efforts undertaken in the northern Gulf of Mexico for more than ten years have resulted in synergistic research with multiple means of federal support. Major grants include the FEMA Flood Insurance Studies, the NOAA / NOS Ecological Effects of Sea Level Rise Program, as well as the NSF Coastal SEES Program. Through a careful development of a collective enterprise the results from these and other individual programs (e.g., NOAA Sea Grant College, DHS Center of Excellence, NSF Rapid Response) have been elevated to achieve transdisciplinary outcomes. A direct product of the synergy is a system of systems approach to bio-geophysical science with the inclusion of socioeconomic processes.

A preliminary design study for a cosmic X-ray spectrometer

NASA Technical Reports Server (NTRS)

1972-01-01

The results are described of theoretical and experimental investigations aimed at the development of a curved crystal cosmic X-ray spectrometer to be used at the focal plane of the large orbiting X-ray telescope on the third High Energy Astronomical Observatory. The effort was concentrated on the development of spectrometer concepts and their evaluation by theoretical analysis, computer simulation, and laboratory testing with breadboard arrangements of crystals and detectors. In addition, a computer-controlled facility for precision testing and evaluation of crystals in air and vacuum was constructed. A summary of research objectives and results is included.

A focal plane metrology system and PSF centroiding experiment

NASA Astrophysics Data System (ADS)

Li, Haitao; Li, Baoquan; Cao, Yang; Li, Ligang

2016-10-01

In this paper, we present an overview of a detector array equipment metrology testbed and a micro-pixel centroiding experiment currently under development at the National Space Science Center, Chinese Academy of Sciences. We discuss on-going development efforts aimed at calibrating the intra-/inter-pixel quantum efficiency and pixel positions for scientific grade CMOS detector, and review significant progress in achieving higher precision differential centroiding for pseudo star images in large area back-illuminated CMOS detector. Without calibration of pixel positions and intrapixel response, we have demonstrated that the standard deviation of differential centroiding is below 2.0e-3 pixels.

Multilayer Fiber Interfaces for Improved Environmental Resistance and Slip in Carbon Fiber Reinforced Composites

NASA Technical Reports Server (NTRS)

Babcock, Jason R.; Ramachandran, Gautham; Williams, Brian E.; Effinger, Michael R.

2004-01-01

Ultraviolet-enhanced chemical vapor deposition (UVCVD) has been developed to lower the required substrate temperature thereby allowing for the application of metal oxide-based coatings to carbon and ceramic fibers without causing significant fiber damage. An effort to expand this capability to other ceramic phases chosen to maximize oxidation protection in the likely event of matrix cracking and minimize possible reaction between the coating and fiber during long-term high temperature use will be presented along with studies aimed at the demonstration of these and other benefits for the next-generation interface coating systems being developed herein.

Genetic Design Automation: engineering fantasy or scientific renewal?

PubMed Central

Lux, Matthew W.; Bramlett, Brian W.; Ball, David A.; Peccoud, Jean

2013-01-01

Synthetic biology aims to make genetic systems more amenable to engineering, which has naturally led to the development of Computer-Aided Design (CAD) tools. Experimentalists still primarily rely on project-specific ad-hoc workflows instead of domain-specific tools, suggesting that CAD tools are lagging behind the front line of the field. Here, we discuss the scientific hurdles that have limited the productivity gains anticipated from existing tools. We argue that the real value of efforts to develop CAD tools is the formalization of genetic design rules that determine the complex relationships between genotype and phenotype. PMID:22001068

Timeline: Targeted Treatment of Hepatitis C Virus.

PubMed

Teitzel, Gail

2016-09-22

Chronic hepatitis C virus infection can cause liver cirrhosis and cancer, and early treatment options were non-specific and could be toxic. Work aimed at elucidating the viral life cycle has led to better treatment options through the development of direct-acting antivirals, as exemplified by the work of Ralf Bartenschlager, Charles Rice, and Michael Sofia who have received the Lasker∼DeBakey Clinical Medical Research Award for their work on this effort. Key events in understanding HCV replication and development of direct-acting antivirals are shown in this Timeline. Copyright © 2016 Elsevier Inc. All rights reserved.

Fuel cycle cost reduction through Westinghouse fuel design and core management

DOE Office of Scientific and Technical Information (OSTI.GOV)

Frank, F.J.; Scherpereel, L.R.

1985-11-01

This paper describes advances in Westinghouse nuclear fuel and their impact on fuel cycle cost. Recent fabrication development has been aimed at maintaining high integrity, increased operating flexibility, longer operating cycles, and improved core margins. Development efforts at Westinghouse toward meeting these directions have culminated in VANTAGE 5 fuel. The current trend toward longer operating cycles provides a further driving force to minimize the resulting inherent increase in fuel cycle costs by further increases in region discharge burnup. Westinghouse studies indicate the capability of currently offered products to meet cycle lengths up to 24 months.

NSSDC activities with 12-inch optical disk drives

NASA Technical Reports Server (NTRS)

Lowrey, Barbara E.; Lopez-Swafford, Brian

1986-01-01

The development status of optical-disk data transfer and storage technology at the National Space Science Data Center (NSSDC) is surveyed. The aim of the R&D program is to facilitate the exchange of large volumes of data. Current efforts focus on a 12-inch 1-Gbyte write-once/read-many disk and a disk drive which interfaces with VAX/VMS computer systems. The history of disk development at NSSDC is traced; the results of integration and performance tests are summarized; the operating principles of the 12-inch system are explained and illustrated with diagrams; and the need for greater standardization is indicated.

The Glycan Microarray Story from Construction to Applications.

PubMed

Hyun, Ji Young; Pai, Jaeyoung; Shin, Injae

2017-04-18

Not only are glycan-mediated binding processes in cells and organisms essential for a wide range of physiological processes, but they are also implicated in various pathological processes. As a result, elucidation of glycan-associated biomolecular interactions and their consequences is of great importance in basic biological research and biomedical applications. In 2002, we and others were the first to utilize glycan microarrays in efforts aimed at the rapid analysis of glycan-associated recognition events. Because they contain a number of glycans immobilized in a dense and orderly manner on a solid surface, glycan microarrays enable multiple parallel analyses of glycan-protein binding events while utilizing only small amounts of glycan samples. Therefore, this microarray technology has become a leading edge tool in studies aimed at elucidating roles played by glycans and glycan binding proteins in biological systems. In this Account, we summarize our efforts on the construction of glycan microarrays and their applications in studies of glycan-associated interactions. Immobilization strategies of functionalized and unmodified glycans on derivatized glass surfaces are described. Although others have developed immobilization techniques, our efforts have focused on improving the efficiencies and operational simplicity of microarray construction. The microarray-based technology has been most extensively used for rapid analysis of the glycan binding properties of proteins. In addition, glycan microarrays have been employed to determine glycan-protein interactions quantitatively, detect pathogens, and rapidly assess substrate specificities of carbohydrate-processing enzymes. More recently, the microarrays have been employed to identify functional glycans that elicit cell surface lectin-mediated cellular responses. Owing to these efforts, it is now possible to use glycan microarrays to expand the understanding of roles played by glycans and glycan binding proteins in biological systems.

Advanced lightweight optics development for space applications

NASA Astrophysics Data System (ADS)

Bilbro, James W.

1998-01-01

A considerable amount of effort over the past year has been devoted to exploring ultra-lightweight optics for two specific NASA programs, the Next Generation Space Telescope (NGST), and the High Throughput X-ray Spectrometer (HTXS). Experimental investigations have been undertaken in a variety of materials including glass, composites, nickel, beryllium, Carbon fiber reinforced Silicon Carbide (CSiC), Reaction Bonded Silicon Carbide, Chemical Vapor Deposited Silicon Carbide, and Silicon. Overall results of these investigations will be summarized, and specific details will be provided concerning the in-house development of ultra-lightweight nickel replication for both grazing incidence and normal incidence optics. This will include x-ray test results of the grazing incidence optic and cryogenic test results of the normal incidence optic. The status of two 1.5 meter diameter demonstration mirrors for NGST will also be presented. These two demonstrations are aimed at establishing the capability to manufacture and test mirrors that have an areal density of 15 kilograms per square meter. Efforts in thin membrane mirrors and Fresnel lenses will also be briefly discussed.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Trivelpiece, A.W.

In January 1996, when the management and operation (M and O) contract for the Oak Ridge National Laboratory (ORNL) was awarded to Lockheed Martin Energy Research Corporation, they were presented with the opportunity to develop and implement a management structure tailored to the Laboratory's needs and functions. In response, they launched a Laboratory-wide reengineering effort and undertook other work with the goal of fostering excellence, relevance, and stewardship in all aspects of the Laboratory's operations. This effort is paying off in improvements in their ability to meet the expectations established for ORNL as a Department of Energy laboratory overseen bymore » the Office of Science: delivering advances in science and technology, securing new capabilities, improving the ability to operate safely and efficiently at reasonable cost, and being a good neighbor. The development of critical outcomes and objectives, now under way in partnership with the Department's Oak Ridge Operations Office, is aimed at providing a performance-based means of determining how ORNL measures up to these expectations.« less

Towards a Global Wetland Observation System: The Geo-Wetlands Initiative

NASA Astrophysics Data System (ADS)

Strauch, Adrian; Geller, Gary; Grobicki, Ania; Hilarides, Lammert; Muro, Javier; Paganini, Marc; Weise, Kathrin

2016-08-01

Wetlands are hot spots of biodiversity and provide a wide range of valuable ecosystem services, but at the same time they globally are one of the fastest declining and most endangered ecosystems. The development of a Global Wetland Observation System (GWOS) that is supported by the Ramsar Convention on Wetlands since 2007 is seen as a step towards improved capabilities for global mapping, monitoring and assessment of wetland ecosystems and their services, status and trends. A newly proposed GEO-Wetlands initiative is taking up this effort and developing the necessary governance and management structures, a community of practice and the necessary scientific and technical outputs to set up this system and maintain it over the long term. This effort is aiming at directly supporting the needs of global conventions and monitoring frameworks as well as users of wetland information on all levels (local to global) to build a platform that provides a knowledge-hub as a baseline for informed ecosystem management and decision-making.

Biomaterial delivery of morphogens to mimic the natural healing cascade in bone.

PubMed

Mehta, Manav; Schmidt-Bleek, Katharina; Duda, Georg N; Mooney, David J

2012-09-01

Complications in treatment of large bone defects using bone grafting still remain. Our understanding of the endogenous bone regeneration cascade has inspired the exploration of a wide variety of growth factors (GFs) in an effort to mimic the natural signaling that controls bone healing. Biomaterial-based delivery of single exogenous GFs has shown therapeutic efficacy, and this likely relates to its ability to recruit and promote replication of cells involved in tissue development and the healing process. However, as the natural bone healing cascade involves the action of multiple factors, each acting in a specific spatiotemporal pattern, strategies aiming to mimic the critical aspects of this process will likely benefit from the usage of multiple therapeutic agents. This article reviews the current status of approaches to deliver single GFs, as well as ongoing efforts to develop sophisticated delivery platforms to deliver multiple lineage-directing morphogens (multiple GFs) during bone healing. Copyright © 2012 Elsevier B.V. All rights reserved.

Spacecraft environmental interactions: A joint Air Force and NASA research and technology program

NASA Technical Reports Server (NTRS)

Pike, C. P.; Purvis, C. K.; Hudson, W. R.

1985-01-01

A joint Air Force/NASA comprehensive research and technology program on spacecraft environmental interactions to develop technology to control interactions between large spacecraft systems and the charged-particle environment of space is described. This technology will support NASA/Department of Defense operations of the shuttle/IUS, shuttle/Centaur, and the force application and surveillance and detection missions, planning for transatmospheric vehicles and the NASA space station, and the AFSC military space system technology model. The program consists of combined contractual and in-house efforts aimed at understanding spacecraft environmental interaction phenomena and relating results of ground-based tests to space conditions. A concerted effort is being made to identify project-related environmental interactions of concern. The basic properties of materials are being investigated to develop or modify the materials as needed. A group simulation investigation is evaluating basic plasma interaction phenomena to provide inputs to the analytical modeling investigation. Systems performance is being evaluated by both groundbased tests and analysis.

COINS: A composites information database system

NASA Technical Reports Server (NTRS)

Siddiqi, Shahid; Vosteen, Louis F.; Edlow, Ralph; Kwa, Teck-Seng

1992-01-01

An automated data abstraction form (ADAF) was developed to collect information on advanced fabrication processes and their related costs. The information will be collected for all components being fabricated as part of the ACT program and include in a COmposites INformation System (COINS) database. The aim of the COINS development effort is to provide future airframe preliminary design and fabrication teams with a tool through which production cost can become a deterministic variable in the design optimization process. The effort was initiated by the Structures Technology Program Office (STPO) of the NASA LaRC to implement the recommendations of a working group comprised of representatives from the commercial airframe companies. The principal working group recommendation was to re-institute collection of composite part fabrication data in a format similar to the DOD/NASA Structural Composites Fabrication Guide. The fabrication information collection form was automated with current user friendly computer technology. This work in progress paper describes the new automated form and features that make the form easy to use by an aircraft structural design-manufacturing team.

Automating the parallel processing of fluid and structural dynamics calculations

NASA Technical Reports Server (NTRS)

Arpasi, Dale J.; Cole, Gary L.

1987-01-01

The NASA Lewis Research Center is actively involved in the development of expert system technology to assist users in applying parallel processing to computational fluid and structural dynamic analysis. The goal of this effort is to eliminate the necessity for the physical scientist to become a computer scientist in order to effectively use the computer as a research tool. Programming and operating software utilities have previously been developed to solve systems of ordinary nonlinear differential equations on parallel scalar processors. Current efforts are aimed at extending these capabilities to systems of partial differential equations, that describe the complex behavior of fluids and structures within aerospace propulsion systems. This paper presents some important considerations in the redesign, in particular, the need for algorithms and software utilities that can automatically identify data flow patterns in the application program and partition and allocate calculations to the parallel processors. A library-oriented multiprocessing concept for integrating the hardware and software functions is described.

Recent advances in engineering topography mediated antibacterial surfaces

PubMed Central

Hasan, Jafar

2015-01-01

The tendency of bacterial cells to adhere and colonize a material surface leading to biofilm formation is a fundamental challenge underlying many different applications including microbial infections associated with biomedical devices and products. Although, bacterial attachment to surfaces has been extensively studied in the past, the effect of surface topography on bacteria–material interactions has received little attention until more recently. We review the recent progress in surface topography based approaches for engineering antibacterial surfaces. Biomimicry of antibacterial surfaces in nature is a popular strategy. Whereas earlier endeavors in the field aimed at minimizing cell attachment, more recent efforts have focused on developing bactericidal surfaces. However, not all such topography mediated bactericidal surfaces are necessarily cytocompatible thus underscoring the need for continued efforts for research in this area for developing antibacterial and yet cytocompatible surfaces for use in implantable biomedical applications. This mini-review provides a brief overview of the current strategies and challenges in the emerging field of topography mediated antibacterial surfaces. PMID:26372264

Enabling personalized cancer medicine decisions: The challenging pharmacological approach of PBPK models for nanomedicine and pharmacogenomics (Review).

PubMed

Vizirianakis, Ioannis S; Mystridis, George A; Avgoustakis, Konstantinos; Fatouros, Dimitrios G; Spanakis, Marios

2016-04-01

The existing tumor heterogeneity and the complexity of cancer cell biology critically demand powerful translational tools with which to support interdisciplinary efforts aiming to advance personalized cancer medicine decisions in drug development and clinical practice. The development of physiologically based pharmacokinetic (PBPK) models to predict the effects of drugs in the body facilitates the clinical translation of genomic knowledge and the implementation of in vivo pharmacology experience with pharmacogenomics. Such a direction unequivocally empowers our capacity to also make personalized drug dosage scheme decisions for drugs, including molecularly targeted agents and innovative nanoformulations, i.e. in establishing pharmacotyping in prescription. In this way, the applicability of PBPK models to guide individualized cancer therapeutic decisions of broad clinical utility in nanomedicine in real-time and in a cost-affordable manner will be discussed. The latter will be presented by emphasizing the need for combined efforts within the scientific borderlines of genomics with nanotechnology to ensure major benefits and productivity for nanomedicine and personalized medicine interventions.

Recent advances in engineering topography mediated antibacterial surfaces

NASA Astrophysics Data System (ADS)

Hasan, Jafar; Chatterjee, Kaushik

2015-09-01

The tendency of bacterial cells to adhere and colonize a material surface leading to biofilm formation is a fundamental challenge underlying many different applications including microbial infections associated with biomedical devices and products. Although, bacterial attachment to surfaces has been extensively studied in the past, the effect of surface topography on bacteria-material interactions has received little attention until more recently. We review the recent progress in surface topography based approaches for engineering antibacterial surfaces. Biomimicry of antibacterial surfaces in nature is a popular strategy. Whereas earlier endeavors in the field aimed at minimizing cell attachment, more recent efforts have focused on developing bactericidal surfaces. However, not all such topography mediated bactericidal surfaces are necessarily cytocompatible thus underscoring the need for continued efforts for research in this area for developing antibacterial and yet cytocompatible surfaces for use in implantable biomedical applications. This mini-review provides a brief overview of the current strategies and challenges in the emerging field of topography mediated antibacterial surfaces.

Advancing therapeutic strategies for inherited retinal degeneration: recommendations from the Monaciano Symposium.

PubMed

Thompson, Debra A; Ali, Robin R; Banin, Eyal; Branham, Kari E; Flannery, John G; Gamm, David M; Hauswirth, William W; Heckenlively, John R; Iannaccone, Alessandro; Jayasundera, K Thiran; Khan, Naheed W; Molday, Robert S; Pennesi, Mark E; Reh, Thomas A; Weleber, Richard G; Zacks, David N

2015-02-09

Although rare in the general population, retinal dystrophies occupy a central position in current efforts to develop innovative therapies for blinding diseases. This status derives, in part, from the unique biology, accessibility, and function of the retina, as well as from the synergy between molecular discoveries and transformative advances in functional assessment and retinal imaging. The combination of these factors has fueled remarkable progress in the field, while at the same time creating complex challenges for organizing collective efforts aimed at advancing translational research. The present position paper outlines recent progress in gene therapy and cell therapy for this group of disorders, and presents a set of recommendations for addressing the challenges remaining for the coming decade. It is hoped that the formulation of these recommendations will stimulate discussions among researchers, funding agencies, industry, and policy makers that will accelerate the development of safe and effective treatments for retinal dystrophies and related diseases. Copyright 2015 The Association for Research in Vision and Ophthalmology, Inc.

Park system concept for environmental sustainabilityin urban spatial development

NASA Astrophysics Data System (ADS)

Uniaty, Q.

2018-01-01

Urban Park System is an integrated concept between nature system and urban life. The problems caused by urban population activity resulted in the need to increase the balance between two systems. Establishment of urban park system is a response to the need for resilience of urban space structures. As an ideal requirement it needs to be built integration between the ecological, social, economic, aesthetic aspects of urban landscape architecture. The methodology was developed based on an approach to issues affecting the conditions due to urban issues and its relation to the development efforts of urban park system; Observation of Jakarta problem was obtained based on published studies and data, literature, characteristic and potential analyzes, local physical, from limited field observations. Both are simple methods aimed to describe the nature of a condition as well as form characteristics of problems in controlling the development of region, to examine the causes and symptoms. This method try to assess an object study compared between the conditions before and after. The benefits of urban park system development will not only improve the urban environment, but the value of urban pride, identity and control urban growth in line with efforts to improve the balance between conservation and development. Integrated urban park system will enhance the multifunctional role, connectivity, habitability, durability, identity and investment.

Suicide in developing countries (1): frequency, distribution, and association with socioeconomic indicators.

PubMed

Vijayakumar, Lakshmi; Nagaraj, K; Pirkis, Jane; Whiteford, Harvey

2005-01-01

Suicide is a global public health problem, but relatively little epidemiological investigation of the phenomenon has occurred in developing countries. This paper aims to (1) examine the availability of rate data in developing countries, (2) provide a description of the frequency and distribution of suicide in those countries for which data are available, and (3) explore the relationship between country-level socioeconomic factors and suicide rates. It is accompanied by two companion papers that consider risk factors and preventive efforts associated with suicide in developing countries, respectively. Using World Health Organization data, we calculated the average annual male, female, and total suicide rates during the 1990s for individual countries and regions (classified according to the Human Development Index [HDI]), and examined the association between a range of socioeconomic indicators and suicide rates. For reasons of data availability, we concentrated on medium HDI countries. Suicide rates in these countries were variable. They were generally comparable with those in high HDI countries from the same region, with some exceptions. High education levels, high telephone density, and high per capita levels of cigarette consumption were associated with high suicide rates; high levels of inequality were associated with low suicide rates. Epidemiological investigations of this kind have the potential to inform suicide prevention efforts in developing countries, and should be encouraged.

International Outreach in Africa - Complementary Efforts Using Common Cyberinfrastructure

NASA Astrophysics Data System (ADS)

Yoksas, T.; Almeida, W. G.; Pandya, R.; Bruintjes, R.; Foote, B.; Heck, S.; Herrmann, S.; Hoswell, E.; Konate, M.; Kucera, P.; Laing, A.; Lamptey, B.; Moncrieff, M.; Ramamurthy, M.; Roberts, R.; Traore, A.; Spangler, T.; Warner, T.; Weingroff, M.; Ribeiro, N. A.; Soares, E.; Nascimento, A.; Lona, J.; Real, J. C.

2008-05-01

For the past few years, the U.S. Unidata Program Center (Unidata, a program in UCAR) and Brazil's Centro de Previsão de Tempo e Estudos Climáticos (CPTEC, a division of INPE) have collaborated in outreach efforts where free-and-open exchange of hydro-meteorological data and the provision of free analysis/visualization tools are helping to build a hemispheric community where data, tools, and best practices in education and research are shared. Data sharing capabilities are being provided by Unidata's Internet Data Distribution (IDD) system, a community-based effort that has been the primary source of real-time meteorological data in the U.S. university community for over a decade. Unidata-CPTEC efforts have resulted in the creation of the Brazilian peer of the North American IDD, the IDD-Brasil, a data sharing network that has extended access to real-time data to over 15 institutions in South America and most recently countries in West Africa and the African Sahel. UCAR and CPTEC are involved in separate, but philosophically-related and complementary outreach efforts in Africa: UCAR has embarked on an effort, The UCAR Africa Initiative, whose goal is assisting in building sustainable atmospheric-sciences capacity in Africa. CPTEC is collaborating with national weather services in three West African countries, universities in Brazil and Portugal, and one private Portuguese company in SICLIMAD, a project aimed at contributing to sustainable development in West Africa. This presentation will provide an overview of the efforts being undertaken as part of The UCAR Africa Initiative; an overview and update on CPTEC's efforts in SICLIMAD; and explore avenues for greater collaboration on African issues and endeavors.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Henzlova, Daniela; Kouzes, R.; McElroy, R.

International safeguards inspectorates (e.g., International Atomic Energy Agency {IAEA}, or Euratom) rely heavily on neutron assay techniques, and in particular, on coincidence counters for the verification of declared nuclear materials under safeguards and for monitoring purposes. While 3He was readily available, the reliability, safety, ease of use, gamma-ray insensitivity, and high intrinsic thermal neutron detection efficiency of 3He-based detectors obviated the need for alternative detector technologies. However, the recent decline of the 3He gas supply has triggered international efforts to develop and field neutron detectors that make use of alternative materials. In response to this global effort, the U.S. Departmentmore » of Energy’s (DOE) National Nuclear Security Administration (NNSA) and Euratom launched a joint effort aimed at bringing together international experts, technology users and developers in the field of nuclear safeguards to discuss and evaluate the proposed 3He alternative materials and technologies. The effort involved a series of two workshops focused on detailed overviews and viability assessments of various 3He alternative technologies for use in nuclear safeguards applications. The key objective was to provide a platform for collaborative discussions and technical presentations organized in a compact, workshop-like format to stimulate interactions among the participants. The meetings culminated in a benchmark exercise providing a unique opportunity for the first inter-comparison of several available alternative technologies. This report provides an overview of the alternative technology efforts presented during the two workshops along with a summary of the benchmarking activities and results. The workshop recommendations and key consensus observations are discussed in the report, and used to outline a proposed path forward and future needs foreseeable in the area of 3He-alternative technologies.« less

Establishing a Framework for Community Modeling in Hydrologic Science: Recommendations from the CUAHSI CHyMP Initiative

NASA Astrophysics Data System (ADS)

Arrigo, J. S.; Famiglietti, J. S.; Murdoch, L. C.; Lakshmi, V.; Hooper, R. P.

2012-12-01

The Consortium of Universities for the Advancement of Hydrologic Science, Inc. (CUAHSI) continues a major effort towards supporting Community Hydrologic Modeling. From 2009 - 2011, the Community Hydrologic Modeling Platform (CHyMP) initiative held three workshops, the ultimate goal of which was to produce recommendations and an implementation plan to establish a community modeling program that enables comprehensive simulation of water anywhere on the North American continent. Such an effort would include connections to and advances in global climate models, biogeochemistry, and efforts of other disciplines that require an understanding of water patterns and processes in the environment. To achieve such a vision will require substantial investment in human and cyber-infrastructure and significant advances in the science of hydrologic modeling and spatial scaling. CHyMP concluded with a final workshop, held March 2011, and produced several recommendations. CUAHSI and the university community continue to advance community modeling and implement these recommendations through several related and follow on efforts. Key results from the final 2011 workshop included agreement among participants that the community is ready to move forward with implementation. It is recognized that initial implementation of this larger effort can begin with simulation capabilities that currently exist, or that can be easily developed. CHyMP identified four key activities in support of community modeling: benchmarking, dataset evaluation and development, platform evaluation, and developing a national water model framework. Key findings included: 1) The community supported the idea of a National Water Model framework; a community effort is needed to explore what the ultimate implementation of a National Water Model is. A true community modeling effort would support the modeling of "water anywhere" and would include all relevant scales and processes. 2) Implementation of a community modeling program could initially focus on continental scale modeling of water quantity (rather than quality). The goal of this initial model is the comprehensive description of water stores and fluxes in such a way to permit linkage to GCM's, biogeochemical, ecological, and geomorphic models. This continental scale focus allows systematic evaluation of our current state of knowledge and data, leverages existing efforts done by large scale modelers, contributes to scientific discovery that informs globally and societal relevant questions, and provides an initial framework to evaluate hydrologic information relevant to other disciplines and a structure into which to incorporate other classes of hydrologic models. 3) Dataset development will be a key aspect of any successful national water model implementation. Our current knowledge of the subsurface is limiting our ability to truly integrate soil and groundwater into large scale models, and to answering critical science questions with societal relevance (i.e. groundwater's influence on climate). 4) The CHyMP workshops and efforts to date have achieved collaboration between university scientists, government agencies and the private sector that must be maintained. Follow on efforts in community modeling should aim at leveraging and maintaining this collaboration for maximum scientific and societal benefit.

New catalysts for coal liquefaction and new nanocrystalline catalysts synthesis methods

DOE Office of Scientific and Technical Information (OSTI.GOV)

Linehan, J.C.; Matson, D.W.; Darab, J.G.

1994-09-01

The use of coal as a source of transportation fuel is currently economically unfavorable due to an abundant world petroleum supply and the relatively high cost of coal liquefaction. Consequently, a reduction in the cost of coal liquefaction, for example by using less and/or less costly catalysts or lower liquefaction temperatures, must be accomplished if coal is to play an significant role as a source of liquid feedstock for the petrochemical industry. The authors and others have investigated the applicability of using inexpensive iron-based catalysts in place of more costly and environmentally hazardous metal catalysts for direct coal liquefaction. Iron-basedmore » catalysts can be effective in liquefying coal and in promoting carbon-carbon bond cleavage in model compounds. The authors have been involved in an ongoing effort to develop and optimize iron-based powders for use in coal liquefaction and related petrochemical applications. Research efforts in this area have been directed at three general areas. The authors have explored ways to optimize the effectiveness of catalyst precursor species through use of nanocrystalline materials and/or finely divided powders. In this effort, the authors have developed two new nanophase material production techniques, Modified Reverse Micelle (MRM) and the Rapid Thermal Decomposition of precursors in Solution (RTDS). A second effort has been aimed at optimizing the effectiveness of catalysts by variations in other factors. To this, the authors have investigated the effect that the crystalline phase has on the capacity of iron-based oxide and oxyhydroxide powders to be effectively converted to an active catalyst phase under liquefaction conditions. And finally, the authors have developed methods to produce active catalyst precursor powders in quantities sufficient for pilot-scale testing. Major results in these three areas are summarized.« less

The Application of Modeling and Simulation in Capacity Management within the ITIL Framework

NASA Technical Reports Server (NTRS)

Rahmani, Sonya; vonderHoff, Otto

2010-01-01

Tightly integrating modeling and simulation techniques into Information Technology Infrastructure Library (ITIL) practices can be one of the driving factors behind a successful and cost-effective capacity management effort for any Information Technology (IT) system. ITIL is a best practices framework for managing IT infrastructure, development and operations. Translating ITIL theory into operational reality can be a challenge. This paper aims to highlight how to best integrate modeling and simulation into an ITIL implementation. For cases where the project team initially has difficulty gaining consensus on investing in modeling and simulation resources, a clear definition for M&S implementation into the ITIL framework, specifically its role in supporting Capacity Management, is critical to gaining the support required to garner these resources. This implementation should also help to clearly define M&S support to the overall system mission. This paper will describe the development of an integrated modeling approach and how best to tie M&S to definitive goals for evaluating system capacity and performance requirements. Specifically the paper will discuss best practices for implementing modeling and simulation into ITIL. These practices hinge on implementing integrated M&S methods that 1) encompass at least two or more predictive modeling techniques, 2) complement each one's respective strengths and weaknesses to support the validation of predicted results, and 3) are tied to the system's performance and workload monitoring efforts. How to structure two forms of modeling: statistical and simUlation in the development of "As Is" and "To Be" efforts will be used to exemplify the integrated M&S methods. The paper will show how these methods can better support the project's overall capacity management efforts.

The Challenge: To Change the Odds for Youth by Changing the Way We Do Business--All Youth Ready for College, Work & Life

ERIC Educational Resources Information Center

Forum for Youth Investment, 2008

2008-01-01

The Challenge is the definitive guide to the key ideas and resources behind Ready by 21. The Ready by 21 challenge aims to develop a solution for a common dilemma--too few young people are entering adulthood ready and our collective efforts to make a difference are far too fragmented to have a big impact. As part of the Forum's solution, leaders…

Development of a Combination Therapy for Prostate Cancer by Targeting Stat3 and HIF-1alpha

DTIC Science & Technology

2011-07-01

isolated several novel molecules from Chinese herbal medicines. After activity tests of these molecules, we found one compound, TEL, that is a...research plan with three aims to expand these efforts. (1) To isolate and synthesize additional novel compounds from Chinese herbal medicines for... supplemented with 10% FBS, 100 units/ml penicillin, and 100 units/ ml streptomycin and maintained in a 378C CO2 incubator. 2 Reddyet al. The Prostate

The Higher Education Act, Title II-C Program: Strengthening Research Library Resources. A Ten-Year Profile and an Assessment of the Program's Effects upon the Nation's Scholarship.

ERIC Educational Resources Information Center

Streit, Samuel Allen

The aim of this study is to trace how the Title II-C program has facilitated scholarly access to research materials across the United States. It is intended to give evidence of the importance of the Title II-C Program to libraries' efforts toward developing, preserving, and sharing their resources with the nation's scholars. The study consists of…

Optical and acoustic metamaterials: superlens, negative refractive index and invisibility cloak

NASA Astrophysics Data System (ADS)

Wong, Zi Jing; Wang, Yuan; O'Brien, Kevin; Rho, Junsuk; Yin, Xiaobo; Zhang, Shuang; Fang, Nicholas; Yen, Ta-Jen; Zhang, Xiang

2017-08-01

Metamaterials are artificially engineered materials that exhibit novel properties beyond natural materials. By carefully designing the subwavelength unit cell structures, unique effective properties that do not exist in nature can be attained. Our metamaterial research aims to develop new subwavelength structures with unique physics and experimentally demonstrate unprecedented properties. Here we review our research efforts in optical and acoustic metamaterials in the past 15 years which may lead to exciting applications in communications, sensing and imaging.

Modeling Near-Crack-Tip Plasticity from Nano- to Micro-Scales

NASA Technical Reports Server (NTRS)

Glaessgen, Edward H.; Saether, Erik; Hochhalter, Jake D.; Yamakov, Vesselin I.

2010-01-01

Several efforts that are aimed at understanding the plastic deformation mechanisms related to crack propagation at the nano-, meso- and micro-length scales including atomistic simulation, discrete dislocation plasticity, strain gradient plasticity and crystal plasticity are discussed. The paper focuses on discussion of newly developed methodologies and their application to understanding damage processes in aluminum and its alloys. Examination of plastic mechanisms as a function of increasing length scale illustrates increasingly complex phenomena governing plasticity

Bridging the health security divide: department of defense support for the global health security agenda.

PubMed

Moudy, Robin M; Ingerson-Mahar, Michael; Kanter, Jordan; Grant, Ashley M; Fisher, Dara R; Jones, Franca R

2014-01-01

In 2011, President Obama addressed the United Nations General Assembly and urged the global community to come together to prevent, detect, and fight every kind of biological danger, whether a pandemic, terrorist threat, or treatable disease. Over the past decade, the United States and key international partners have addressed these dangers through a variety of programs and strategies aimed at developing and enhancing countries' capacity to rapidly detect, assess, report, and respond to acute biological threats. Despite our collective efforts, however, an increasingly interconnected world presents heightened opportunities for human, animal, and zoonotic diseases to emerge and spread globally. Further, the technical capabilities required to develop biological agents into a weapon are relatively low. The launch of the Global Health Security Agenda (GHSA) provides an opportunity for the international community to enhance the linkages between the health and security sectors, accelerating global efforts to prevent avoidable epidemics and bioterrorism, detect threats early, and respond rapidly and effectively to biological threats. The US Department of Defense (DoD) plays a key role in achieving GHSA objectives through its force health protection, threat reduction, and biodefense efforts at home and abroad. This article focuses on GHSA activities conducted in the DoD Office of the Assistant Secretary of Defense for Nuclear, Chemical, and Biological Defense.

Sustained attention in infancy as a longitudinal predictor of self-regulatory functions.

PubMed

Johansson, Maria; Marciszko, Carin; Gredebäck, Gustaf; Nyström, Pär; Bohlin, Gunilla

2015-11-01

Previous literature suggests that attention processes such as sustained attention would constitute a developmental foundation for the self-regulatory functions executive functioning and effortful control (e.g., Garon, Bryson, & Smith, 2008; Rothbart, Derryberry, & Posner, 1994). Our main aim was to test this hypothesis by studying whether sustained attention at age 1 year can predict individual differences in self-regulatory functions at age 2 years. Longitudinal data from 66 infants and their parents were included in the study. Sustained attention was assessed during free play at age 1 year; executive functioning, measured using an eye-tracking version of the A-not-B task, and effortful control, measured using parental ratings, were assessed at both age 1 and age 2 years. The results did support a longitudinal prediction of individual differences in 2-year-olds' self-regulatory functions as a function of sustained attention at age 1 year. We also found significant improvement in both executive functioning and effortful control over time, and the two self-regulatory constructs were related in toddlerhood but not in infancy. The study helps increase our understanding of the early development of self-regulatory functions necessary for identifying developmental risks and, in the future, for developing new interventions. Copyright © 2015 Elsevier Inc. All rights reserved.

Lidar Technology at the Goddard Laser and Electro-Optics Branch

NASA Technical Reports Server (NTRS)

Heaps, William S.; Obenschain, Arthur F. (Technical Monitor)

2000-01-01

The Laser and Electro-Optics Branch at Goddard Space flight Center was established about three years ago to provide a focused center of engineering support and technology development in these disciplines with an emphasis on spaced based instruments for Earth and Space Science. The Branch has approximately 15 engineers and technicians with backgrounds in physics, optics, and electrical engineering. Members of the Branch are currently supporting a number of space based lidar efforts as well as several technology efforts aimed at enabling future missions. The largest effort within the Branch is support of the Ice, Cloud, and land Elevation Satellite (ICESAT) carrying the Geoscience Laser Altimeter System (GLAS) instrument. The ICESAT/GLAS primary science objectives are: 1) To determine the mass balance of the polar ice sheets and their contributions to global sea level change; and 2) To obtain essential data for prediction of future changes in ice volume and sea-level. The secondary science objectives are: 1) To measure cloud heights and the vertical structure of clouds and aerosols in the atmosphere; 2) To map the topography of land surfaces; and 3) To measure roughness, reflectivity, vegetation heights, snow-cover, and sea-ice surface characteristics. Our efforts have concentrated on the GLAS receiver component development, the Laser Reference Sensor for the Stellar Reference System, the GLAS fiber optics subsystems, and the prelaunch calibration facilities. We will report on our efforts in the development of the space qualified interference filter [Allan], etalon filter, photon counting detectors, etalor/laser tracking system, and instrument fiber optics, as well as specification and selection of the star tracker and development of the calibration test bed. We are also engaged in development work on lidar sounders for chemical species. We are developing new lidar technology to enable a new class of miniature lidar instruments that are compatible with small Discovery-class orbiters now in the NASA planetary program. The purpose of the lidar is to continuously profile the water vapor and dust in the Mars atmosphere from orbit in order to quantify its dynamics, their relationship in the diurnal cycles, and to infer water vapor exchange with the Mars surface. To remotely measure the water-vapor height profiles, we will use the differential absorption lidar (DIAL) technique. We are also developing a laser sensor for measuring the total column content of CO2 in the atmosphere of the earth. CO2 is the principal greenhouse gas and has increased by roughly 80 ppm in the last century and a half. We will report our efforts in the development of the laser transmitter and photon counting detector components for a Mars Orbiting DIAL system and for the CO2 sounder.

Aiming High and Falling Short: California's Eighth-Grade Algebra-for-All Effort

ERIC Educational Resources Information Center

Domina, Thurston; McEachin, Andrew; Penner, Andrew; Penner, Emily

2015-01-01

The United States is in the midst of an effort to intensify middle school mathematics curricula by enrolling more 8th graders in Algebra. California is at the forefront of this effort, and in 2008, the state moved to make Algebra the accountability benchmark test for 8th-grade mathematics. This article takes advantage of this unevenly implemented…

Progress in the Visualization and Mining of Chemical and Target Spaces.

PubMed

Medina-Franco, José L; Aguayo-Ortiz, Rodrigo

2013-12-01

Chemogenomics is a growing field that aims to integrate the chemical and target spaces. As part of a multi-disciplinary effort to achieve this goal, computational methods initially developed to visualize the chemical space of compound collections and mine single-target structure-activity relationships, are being adapted to visualize and mine complex relationships in chemogenomics data sets. Similarly, the growing evidence that clinical effects are many times due to the interaction of single or multiple drugs with multiple targets, is encouraging the development of novel methodologies that are integrated in multi-target drug discovery endeavors. Herein we review advances in the development and application of approaches to generate visual representations of chemical space with particular emphasis on methods that aim to explore and uncover relationships between chemical and target spaces. Also, progress in the data mining of the structure-activity relationships of sets of compounds screened across multiple targets are discussed in light of the concept of activity landscape modeling. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Burnout and effort-reward-imbalance in a sample of 949 German teachers.

PubMed

Unterbrink, Thomas; Hack, Anna; Pfeifer, Ruth; Buhl-Griesshaber, Veronika; Müller, Udo; Wesche, Helmut; Frommhold, Markus; Scheuch, Klaus; Seibt, Reingard; Wirsching, Michael; Bauer, Joachim

2007-04-01

High rates of teachers' premature retirement initiated a research investigating their occupational burden. The aim of this study was to elaborate on and extend previous investigations exploring (1) teacher burnout and (2) the relationship between teachers' efforts and their rewards. A sample of 949 German teachers in 10 Gymnasien (grammar schools) and 79 Hauptschulen (secondary modern schools) was investigated applying the Maslach Burnout Inventory (MBI-D) and the Effort Reward Imbalance Inventory (ERI). Compared with other studies investigating burnout in employees, we found high rates of burnout symptoms such as emotional exhaustion, depersonalisation, and low personal accomplishment. Male teachers showed significantly lower personal accomplishment and more depersonalization than female teachers. With respect to school types, teachers in Hauptschulen were more often affected by emotional exhaustion and showed more depersonalization. Part-time teachers felt less personal accomplishment than full-time teachers. The ERI cut off was exceeded by 21.6% of all teachers indicating that this subgroup is affected by an imbalance between too much effort and too little reward. With respect to the ERI, significant differences were found for school types, with a higher proportion of Hauptschulen teachers being above this cut off. At present, the working situation of teachers appears to be characterized by a perceived imbalance of effort and reward and is associated with a high risk of developing burnout symptoms.

Associations of Occupational Stressors, Perceived Organizational Support, and Psychological Capital with Work Engagement among Chinese Female Nurses.

PubMed

Wang, Xiaoxi; Liu, Li; Zou, Futing; Hao, Junhui; Wu, Hui

2017-01-01

This study aimed to explore the associations of occupational stressors (extrinsic effort, reward, and overcommitment), perceived organizational support (POS), and psychological capital (PsyCap) and its components (self-efficacy, hope, resilience, and optimism) with work engagement and the mediating roles of PsyCap and its components among Chinese female nurses within the framework of the job demands-resources (JD-R) model. A cross-sectional sample (1,330) completed the Utrecht Work Engagement Scale, Effort-Reward Imbalance Scale, Survey of POS, and PsyCap Questionnaire, and effective respondents were 1,016 (76.4%). Hierarchical regression analysis and Preacher and Hayes' asymptotic and resampling strategies were used. Extrinsic effort was negatively associated with vigor, dedication, and absorption, while POS, PsyCap, and hope were positively associated with them. Reward and overcommitment were positively associated with dedication and absorption. Optimism was positively associated with vigor and dedication. Optimism mediated the associations of extrinsic effort, reward, and POS with vigor and dedication. PsyCap and hope mediated the associations of POS with vigor, dedication, and absorption. There is a low level of work engagement among Chinese female nurses. Extrinsic effort could reduce work engagement, while reward, overcommitment, POS, PsyCap, hope, and optimism could enhance work engagement. Hospital managers should develop the PsyCap of female nurses through controlling occupational stressors and establishing supportive organizational climate to enhance their work engagement.

Associations of Occupational Stressors, Perceived Organizational Support, and Psychological Capital with Work Engagement among Chinese Female Nurses

PubMed Central

Wang, Xiaoxi; Zou, Futing; Hao, Junhui

2017-01-01

This study aimed to explore the associations of occupational stressors (extrinsic effort, reward, and overcommitment), perceived organizational support (POS), and psychological capital (PsyCap) and its components (self-efficacy, hope, resilience, and optimism) with work engagement and the mediating roles of PsyCap and its components among Chinese female nurses within the framework of the job demands-resources (JD-R) model. A cross-sectional sample (1,330) completed the Utrecht Work Engagement Scale, Effort-Reward Imbalance Scale, Survey of POS, and PsyCap Questionnaire, and effective respondents were 1,016 (76.4%). Hierarchical regression analysis and Preacher and Hayes' asymptotic and resampling strategies were used. Extrinsic effort was negatively associated with vigor, dedication, and absorption, while POS, PsyCap, and hope were positively associated with them. Reward and overcommitment were positively associated with dedication and absorption. Optimism was positively associated with vigor and dedication. Optimism mediated the associations of extrinsic effort, reward, and POS with vigor and dedication. PsyCap and hope mediated the associations of POS with vigor, dedication, and absorption. There is a low level of work engagement among Chinese female nurses. Extrinsic effort could reduce work engagement, while reward, overcommitment, POS, PsyCap, hope, and optimism could enhance work engagement. Hospital managers should develop the PsyCap of female nurses through controlling occupational stressors and establishing supportive organizational climate to enhance their work engagement. PMID:28168198

Genomics Education for the Public: Perspectives of Genomic Researchers and ELSI Advisors

PubMed Central

Jones, Sondra Smolek; Markey, Janell M.; Byerly, Katherine W.; Roberts, Megan C.

2014-01-01

Aims: For more than two decades genomic education of the public has been a significant challenge. As genomic information becomes integrated into daily life and routine clinical care, the need for public education is even more critical. We conducted a pilot study to learn how genomic researchers and ethical, legal, and social implications advisors who were affiliated with large-scale genomic variation studies have approached the issue of educating the public about genomics. Methods/Results: Semi-structured telephone interviews were conducted with researchers and advisors associated with the SNP/HAPMAP studies and the Cancer Genome Atlas Study. Respondents described approach(es) associated with educating the public about their study. Interviews were audio-recorded, transcribed, coded, and analyzed by team review. Although few respondents described formal educational efforts, most provided recommendations for what should/could be done, emphasizing the need for an overarching entity(s) to take responsibility to lead the effort to educate the public. Opposing views were described related to: who this should be; the overall goal of the educational effort; and the educational approach. Four thematic areas emerged: What is the rationale for educating the public about genomics?; Who is the audience?; Who should be responsible for this effort?; and What should the content be? Policy issues associated with these themes included the need to agree on philosophical framework(s) to guide the rationale, content, and target audiences for education programs; coordinate previous/ongoing educational efforts; and develop a centralized knowledge base. Suggestions for next steps are presented. Conclusion: A complex interplay of philosophical, professional, and cultural issues can create impediments to genomic education of the public. Many challenges, however, can be addressed by agreement on a guiding philosophical framework(s) and identification of a responsible entity(s) to provide leadership for developing/overseeing an appropriate infrastructure to support the coordination/integration/sharing and evaluation of educational efforts, benefiting consumers and professionals. PMID:24495163

Nanoparticles: pharmacological and toxicological significance

PubMed Central

Medina, C; Santos-Martinez, M J; Radomski, A; Corrigan, O I; Radomski, M W

2007-01-01

Nanoparticles are tiny materials (<1000 nm in size) that have specific physicochemical properties different to bulk materials of the same composition and such properties make them very attractive for commercial and medical development. However, nanoparticles can act on living cells at the nanolevel resulting not only in biologically desirable, but also in undesirable effects. In contrast to many efforts aimed at exploiting desirable properties of nanoparticles for medicine, there are limited attempts to evaluate potentially undesirable effects of these particles when administered intentionally for medical purposes. Therefore, there is a pressing need for careful consideration of benefits and side effects of the use of nanoparticles in medicine. This review article aims at providing a balanced update of these exciting pharmacological and potentially toxicological developments. The classes of nanoparticles, the current status of nanoparticle use in pharmacology and therapeutics, the demonstrated and potential toxicity of nanoparticles will be discussed. PMID:17245366

Healthy Eating and Activity Across the Lifespan (HEAL): A call to action to integrate research, clinical practice, policy, and community resources to address weight-related health disparities.

PubMed

Berge, Jerica M; Adamek, Margaret; Caspi, Caitlin; Loth, Katie A; Shanafelt, Amy; Stovitz, Steven D; Trofholz, Amanda; Grannon, Katherine Y; Nanney, Marilyn S

2017-08-01

Despite intense nationwide efforts to improve healthy eating and physical activity across the lifespan, progress has plateaued. Moreover, health inequities remain. Frameworks that integrate research, clinical practice, policy, and community resources to address weight-related behaviors are needed. Implementation and evaluation of integration efforts also remain a challenge. The purpose of this paper is to: (1) Describe the planning and development process of an integrator entity, HEAL (Healthy Eating and Activity across the Lifespan); (2) present outcomes of the HEAL development process including the HEAL vision, mission, and values statements; (3) define the planned integrator functions of HEAL; and (4) describe the ongoing evaluation of the integration process. HEAL team members used a theoretically-driven, evidence-based, systemic, twelve-month planning process to guide the development of HEAL and to lay the foundation for short- and long-term integration initiatives. Key development activities included a review of the literature and case studies, identifying guiding principles and infrastructure needs, conducting stakeholder/key informant interviews, and continuous capacity building among team members. Outcomes/deliverables of the first year of HEAL included a mission, vision, and values statements; definitions of integration and integrator functions and roles; a set of long-range plans; and an integration evaluation plan. Application of the HEAL integration model is currently underway through community solicited initiatives. Overall, HEAL aims to lead real world integrative work that coalesce across research, clinical practice, and policy with community resources to inspire a culture of health equity aimed at improving healthy eating and physical activity across the lifespan. Copyright © 2017 Elsevier Inc. All rights reserved.

Evidence-based medicine training in a resource-poor country, the importance of leveraging personal and institutional relationships

PubMed Central

Tomatis, Cristina; Taramona, Claudia; Rizo-Patrón, Emiliana; Hernández, Fiorela; Rodríguez, Patricia; Piscoya, Alejandro; Gonzales, Elsa; Gotuzzo, Eduardo; Heudebert, Gustavo; Centor, Robert M.; Estrada, Carlos A.

2011-01-01

Rationale, aims and objectives Efforts to implement evidence-based medicine (EBM) training in developing countries are limited. We describe the results of an international effort to improve research capacity in a developing country; we conducted a course aimed at improving basic EBM attitudes and identified challenges. Method Between 2005 and 2009, we conducted an annual 3-day course in Perú consisting of interactive lectures and case-based workshops. We assessed self-reported competence and importance in EBM using a Likert scale (1 = low, 5 = high). Results Totally 220 clinicians participated. For phase I (2005–2007), self-reported EBM competence increased from a median of 2 to 3 (P < 0.001) and the perceived importance of EBM did not change (median = 5). For phase II (2008–2009), before the course, 8–72% graded their competence very low (score of 1–2). After the course, 67–92% of subjects graded their increase in knowledge very high (score of 4–5). The challenges included limited availability of studies relevant to the local reality written in Spanish, participants’ limited time and lack of long-term follow-up on practice change. Informal discussion and written evaluation from participants were universally in agreement that more training in EBM is needed. Conclusions In an EBM course in a resource-poor country, the baseline self-reported competence and experience on EBM were low, and the course had measurable improvements of self-reported competence, perceived utility and readiness to incorporate EBM into their practices. Similar to developed countries, translational research and building the research capacity in developing countries is critical for translating best available evidence into practice. PMID:21276140

Activities for the remediation of TEPCO's Fukushima Daiichi nuclear power plant

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kinoshita, Hirofumi; Kometani, Yutaka; Asano, Takashi

2013-07-01

With the aim of fulfilling recovery work for the Fukushima Daiichi NPP, technological efforts have been made for the development of a survey robot system, adequate communication infrastructure technologies, high radiation environment compatible gamma cameras, heavy machinery-type robots (ASTACO-SoRa), remote decontamination devices (AROUNDER), and contaminated waste water treatment system. We have developed a new type of absorbents which remove cesium (Cs) and strontium (Sr) simultaneously at a high removal rate of 99 % or more. We will provide valuable solutions and rational systems for waste water treatment using this developed adsorbent as well as other various adsorbents for the recoverymore » of Fukushima Daiichi NPP.« less

Defining attributes of patient safety through a concept analysis.

PubMed

Kim, Linda; Lyder, Courtney H; McNeese-Smith, Donna; Leach, Linda Searle; Needleman, Jack

2015-11-01

The aim of this study was to report an analysis of the concept of patient safety. Despite recent increase in the number of work being done to clarify the concept and standardize measurement of patient safety, there are still huge variations in how the term is conceptualized and how to measure patient safety data across various healthcare settings and in research. Concept analysis. A literature search was conducted through PubMed and Cumulative Index to Nursing and Allied Health Literature, Plus using the terms 'patient safety' in the title and 'concept analysis,' 'attributes' or 'definition' in the title and or abstract. All English language literature published between 2002-2014 were considered for the review. Walker and Avant's method guided this analysis. The defining attributes of patient safety include prevention of medical errors and avoidable adverse events, protection of patients from harm or injury and collaborative efforts by individual healthcare providers and a strong, well-integrated healthcare system. The application of Collaborative Alliance of Nursing Outcomes indicators as empirical referents would facilitate the measurement of patient safety. With the knowledge gained from this analysis, nurses may improve patient surveillance efforts that identify potential hazards before they become adverse events and have a stronger voice in health policy decision-making that influence implementation efforts aimed at promoting patient safety, worldwide. Further studies are needed on development of a conceptual model and framework that can aid with collection and measurement of standardized patient safety data. © 2015 John Wiley & Sons Ltd.

Leadership Class Configuration Interaction Code - Status and Opportunities

NASA Astrophysics Data System (ADS)

Vary, James

2011-10-01

With support from SciDAC-UNEDF (www.unedf.org) nuclear theorists have developed and are continuously improving a Leadership Class Configuration Interaction Code (LCCI) for forefront nuclear structure calculations. The aim of this project is to make state-of-the-art nuclear structure tools available to the entire community of researchers including graduate students. The project includes codes such as NuShellX, MFDn and BIGSTICK that run a range of computers from laptops to leadership class supercomputers. Codes, scripts, test cases and documentation have been assembled, are under continuous development and are scheduled for release to the entire research community in November 2011. A covering script that accesses the appropriate code and supporting files is under development. In addition, a Data Base Management System (DBMS) that records key information from large production runs and archived results of those runs has been developed (http://nuclear.physics.iastate.edu/info/) and will be released. Following an outline of the project, the code structure, capabilities, the DBMS and current efforts, I will suggest a path forward that would benefit greatly from a significant partnership between researchers who use the codes, code developers and the National Nuclear Data efforts. This research is supported in part by DOE under grant DE-FG02-87ER40371 and grant DE-FC02-09ER41582 (SciDAC-UNEDF).

U.S. DOE Progress Towards Developing Low-Cost, High Performance, Durable Polymer Electrolyte Membranes for Fuel Cell Applications

PubMed Central

Houchins, Cassidy; Kleen, Greg J.; Spendelow, Jacob S.; Kopasz, John; Peterson, David; Garland, Nancy L.; Ho, Donna Lee; Marcinkoski, Jason; Martin, Kathi Epping; Tyler, Reginald; Papageorgopoulos, Dimitrios C.

2012-01-01

Low cost, durable, and selective membranes with high ionic conductivity are a priority need for wide-spread adoption of polymer electrolyte membrane fuel cells (PEMFCs) and direct methanol fuel cells (DMFCs). Electrolyte membranes are a major cost component of PEMFC stacks at low production volumes. PEMFC membranes also impose limitations on fuel cell system operating conditions that add system complexity and cost. Reactant gas and fuel permeation through the membrane leads to decreased fuel cell performance, loss of efficiency, and reduced durability in both PEMFCs and DMFCs. To address these challenges, the U.S. Department of Energy (DOE) Fuel Cell Technologies Program, in the Office of Energy Efficiency and Renewable Energy, supports research and development aimed at improving ion exchange membranes for fuel cells. For PEMFCs, efforts are primarily focused on developing materials for higher temperature operation (up to 120 °C) in automotive applications. For DMFCs, efforts are focused on developing membranes with reduced methanol permeability. In this paper, the recently revised DOE membrane targets, strategies, and highlights of DOE-funded projects to develop new, inexpensive membranes that have good performance in hot and dry conditions (PEMFC) and that reduce methanol crossover (DMFC) will be discussed. PMID:24958432

Development and field testing of a consumer shared decision-making training program for adults with low literacy.

PubMed

Muscat, Danielle M; Morony, Suzanne; Shepherd, Heather L; Smith, Sian K; Dhillon, Haryana M; Trevena, Lyndal; Hayen, Andrew; Luxford, Karen; Nutbeam, Don; McCaffery, Kirsten

2015-10-01

Given the scarcity of shared decision-making (SDM) interventions for adults with low literacy, we created a SDM training program tailored to this population to be delivered in adult education settings. Formative evaluation during program development included a review of the problem and previous efforts to address it, qualitative interviews with the target population, program planning and field testing. A comprehensive SDM training program was developed incorporating core SDM elements. The program aimed to improve students' understanding of SDM and to provide them with the necessary skills (understanding probabilistic risks and benefits, personal values and preferences) and self-efficacy to use an existing set of questions (the AskShareKnow questions) as a means to engage in SDM during healthcare interactions. There is an ethical imperative to develop SDM interventions for adults with lower literacy. Generic training programs delivered direct-to-consumers in adult education settings offer promise in a national and international environment where too few initiatives exist. Formative evaluation of the program offers practical insights into developing consumer-focused SDM training. The content of the program can be used as a guide for future efforts to engage consumers in SDM. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

Technical Education Outreach in Materials Science and Technology Based on NASA's Materials Research

NASA Technical Reports Server (NTRS)

Jacobs, James A.

2003-01-01

The grant NAG-1 -2125, Technical Education Outreach in Materials Science and Technology, based on NASA s Materials Research, involves collaborative effort among the National Aeronautics and Space Administration s Langley Research Center (NASA-LaRC), Norfolk State University (NSU), national research centers, private industry, technical societies, colleges and universities. The collaboration aims to strengthen math, science and technology education by providing outreach related to materials science and technology (MST). The goal of the project is to transfer new developments from LaRC s Center for Excellence for Structures and Materials and other NASA materials research into technical education across the nation to provide educational outreach and strengthen technical education. To achieve this goal we are employing two main strategies: 1) development of the gateway website and 2) using the National Educators Workshop: Update in Engineering Materials, Science and Technology (NEW:Updates). We have also participated in a number of national projects, presented talks at technical meetings and published articles aimed at improving k-12 technical education. Through the three years of this project the NSU team developed the successful MST-Online site and continued to upgrade and update it as our limited resources permitted. Three annual NEW:Updates conducted from 2000 though 2002 overcame the challenges presented first by the September 11,2001 terrorist attacks and the slow U.S. economy and still managed to conduct very effective workshops and expand our outreach efforts. Plans began on NEW:Update 2003 to be hosted by NASA Langley as a part of the celebration of the Centennial of Controlled Flight.

2006 NASA Seal/Secondary Air System Workshop; Volume 1

NASA Technical Reports Server (NTRS)

Steinetz, Bruce, M. (Editor); Hendricks, Robert C. (Editor); Delgado, Irebert (Editor)

2007-01-01

The 2006 NASA Seal/Secondary Air System workshop covered the following topics: (i) Overview of NASA s new Exploration Initiative program aimed at exploring the Moon, Mars, and beyond; (ii) Overview of NASA s new fundamental aeronautics technology project; (iii) Overview of NASA Glenn Research Center s seal project aimed at developing advanced seals for NASA s turbomachinery, space, and reentry vehicle needs; (iv) Reviews of NASA prime contractor, vendor, and university advanced sealing concepts including tip clearance control, test results, experimental facilities, and numerical predictions; and (v) Reviews of material development programs relevant to advanced seals development. Turbine engine studies have shown that reducing seal leakages as well as high-pressure turbine (HPT) blade tip clearances will reduce fuel burn, lower emissions, retain exhaust gas temperature margin, and increase range. Several organizations presented development efforts aimed at developing faster clearance control systems and associated technology to meet future engine needs. The workshop also covered several programs NASA is funding to develop technologies for the Exploration Initiative and advanced reusable space vehicle technologies. NASA plans on developing an advanced docking and berthing system that would permit any vehicle to dock to any on-orbit station or vehicle. Seal technical challenges (including space environments, temperature variation, and seal-on-seal operation) as well as plans to develop the necessary "androgynous" seal technologies were reviewed. Researchers also reviewed seal technologies employed by the Apollo command module that serve as an excellent basis for seals for NASA s new Crew Exploration Vehicle (CEV).

Views of nature of science questionnaire: Toward valid and meaningful assessment of learners' conceptions of nature of science

NASA Astrophysics Data System (ADS)

Lederman, Norm G.; Abd-El-Khalick, Fouad; Bell, Randy L.; Schwartz, Renée S.

2002-08-01

Helping students develop informed views of nature of science (NOS) has been and continues to be a central goal for kindergarten through Grade 12 (K-12) science education. Since the early 1960s, major efforts have been undertaken to enhance K-12 students and science teachers' NOS views. However, the crucial component of assessing learners' NOS views remains an issue in research on NOS. This article aims to (a) trace the development of a new open-ended instrument, the Views of Nature of Science Questionnaire (VNOS), which in conjunction with individual interviews aims to provide meaningful assessments of learners' NOS views; (b) outline the NOS framework that underlies the development of the VNOS; (c) present evidence regarding the validity of the VNOS; (d) elucidate the use of the VNOS and associated interviews, and the range of NOS aspects that it aims to assess; and (e) discuss the usefulness of rich descriptive NOS profiles that the VNOS provides in research related to teaching and learning about NOS. The VNOS comes in response to some calls within the science education community to go back to developing standardized forced-choice paper and pencil NOS assessment instruments designed for mass administrations to large samples. We believe that these calls ignore much of what was learned from research on teaching and learning about NOS over the past 30 years. The present state of this line of research necessitates a focus on individual classroom interventions aimed at enhancing learners' NOS views, rather than on mass assessments aimed at describing or evaluating students' beliefs.

The American College of Academic International Medicine 2017 Consensus Statement on International Medical Programs: Establishing a system of objective valuation and quantitative metrics to facilitate the recognition and incorporation of academic international medical efforts into existing promotion and tenure paradigms

PubMed Central

Peck, Gregory L.; Garg, Manish; Arquilla, Bonnie; Gracias, Vicente H.; Anderson III, Harry L.; Miller, Andrew C.; Hansoti, Bhakti; Ferrada, Paula; Firstenberg, Michael S.; Galwankar, Sagar C.; Gist, Ramon E.; Jeanmonod, Donald; Jeanmonod, Rebecca; Krebs, Elizabeth; McDonald, Marian P.; Nwomeh, Benedict; Orlando, James P.; Paladino, Lorenzo; Papadimos, Thomas J.; Ricca, Robert L.; Sakran, Joseph V.; Sharpe, Richard P.; Swaroop, Mamta; Stawicki, Stanislaw P.

2017-01-01

The growth of academic international medicine (AIM) as a distinct field of expertise resulted in increasing participation by individual and institutional actors from both high-income and low-and-middle-income countries. This trend resulted in the gradual evolution of international medical programs (IMPs). With the growing number of students, residents, and educators who gravitate toward nontraditional forms of academic contribution, the need arose for a system of formalized metrics and quantitative assessment of AIM- and IMP-related efforts. Within this emerging paradigm, an institution's “return on investment” from faculty involvement in AIM and participation in IMPs can be measured by establishing equivalency between international work and various established academic activities that lead to greater institutional visibility and reputational impact. The goal of this consensus statement is to provide a basic framework for quantitative assessment and standardized metrics of professional effort attributable to active faculty engagement in AIM and participation in IMPs. Implicit to the current work is the understanding that the proposed system should be flexible and adaptable to the dynamically evolving landscape of AIM – an increasingly important subset of general academic medical activities. PMID:29291172

Diary of a Dabbler: Ecological Influences on an EFL Teacher's Efforts to Study Japanese Informally

ERIC Educational Resources Information Center

Casanave, Christine Pearson

2012-01-01

In this diary study, the author draws from journals written over the course of 8 years working as an English instructor at a Japanese university, with the aim of documenting the influences on her desire to invest effort in the self-study of Japanese (what she refers to as the "ecology of effort"). An ecological perspective reveals the…

Consumer Views on Transportation and Advanced Vehicle Technologies

DOE Office of Scientific and Technical Information (OSTI.GOV)

Singer, Mark

Vehicle manufacturers, U.S. Department of Energy laboratories, universities, private researchers, and organizations from countries around the globe are pursuing advanced vehicle technologies that aim to reduce gasoline and diesel consumption. This report details study findings of broad American public sentiments toward issues surrounding advanced vehicle technologies and is supported by the U.S. Department of Energy Vehicle Technology Office (VTO) in alignment with its mission to develop and deploy these technologies to improve energy security, increase mobility flexibility, reduce transportation costs, and increase environmental sustainability. Understanding and tracking consumer sentiments can influence the prioritization of development efforts by identifying barriers tomore » and opportunities for broad acceptance of new technologies. Predicting consumer behavior toward developing technologies and products is inherently inexact. A person's stated preference given in an interview about a hypothetical setting may not match the preference that is demonstrated in an actual situation. This difference makes tracking actual consumer actions ultimately more valuable in understanding potential behavior. However, when developing technologies are not yet available and actual behaviors cannot be tracked, stated preferences provide some insight into how consumers may react in new circumstances. In this context this report provides an additional source to validate data and a new resource when no data are available. This report covers study data captured from December 2005 through June 2015 relevant to VTO research efforts at the time of the studies. Broadly the report covers respondent sentiments about vehicle fuel economy, future vehicle technology alternatives, ethanol as a vehicle fuel, plug-in electric vehicles, and willingness to pay for vehicle efficiency. This report represents a renewed effort to publicize study findings and make consumer sentiment data available to researchers, policy makers, and the public. Planned reports will follow detailing data from new studies targeting the primary challenges to and opportunities for advanced vehicle technology deployment. The effort continually refines study content to maintain and improve the relevance and validity of results.« less

Assessment of the U.S. Department of Defense Efforts to Develop an Effective Medical Logistics System within the Afghan National Security Forces

DTIC Science & Technology

2011-06-14

aggressively to strengthen measures aimed at ensuring a successful ANSF transition. Ongoing actions include: • Working with CURE International and the ANSF...sustainability include the following ongoing actions: • Working with CURE International and the MoD and MoI to complete, promulgate and implement Standards of Care...approximately June-August 2011. In addition, NTM-A/CSTC-A previously awarded an approximately $1.57M contract with the NGO CURE International to

Post Landsat-D advanced concept evaluation /PLACE/

NASA Technical Reports Server (NTRS)

Alexander, L. D.; Alvarado, U. R.; Flatow, F. S.

1979-01-01

The aim of the Post Landsat-D Advanced Concept Evaluation (PLACE) program was to identify the key technology requirements of earth resources satellite systems for the 1985-2000 period. The program involved four efforts: (1) examination of future needs in the earth resources area, (2) creation of a space systems technology model capable of satisfying these needs, (3) identification of key technology requirements posed by this model, and (4) development of a methodology (PRISM) to assist in the priority structuring of the resulting technologies.

Comprehensive report of the work done under contract AT(40-1)-3329 during the years 1970--1973

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bernheim, F.; Ottolenghi, A.

1973-11-01

During the past three years of the project the principal aims of the effort have been: (1) to establish the quantitative relationship between eosinophilic leukocytes and phospholipase B in all major areas of distribution of these cells; and (2) to develop procedures and approaches for studying the kinetics and regulatory mechanisms of the peripheral eosinophilic population. Both objectives have been accomplished and a number of related and new aspects of the problem have been brought to light. (auth)

Development of Advanced Technologies for Complete Genomic and Proteomic Characterization of Quantized Human Tumor Cells

DTIC Science & Technology

2014-07-01

13. SUPPLEMENTARY NOTES 14. ABSTRACT With the establishment of Glioblastoma ( GBM ) cell lines from GBM patient’s tumor samples and quantized cell...populations of each of the parental GBM cell lines, we have completed most of our major aims of this project. We will continue in our efforts in the...signatures. Whole genome sequencing from two families of GBM patients are now well established and from the basis of the molecular characterization of

Using Mindfulness- and Acceptance-Based Treatments with Clients from Nondominant Cultural and/or Marginalized Backgrounds: Clinical Considerations, Meta-Analysis Findings, and Introduction to the Special Series--Clinical Considerations in Using Acceptance- and Mindfulness-Based Treatments with Diverse Populations

ERIC Educational Resources Information Center

Fuchs, Cara; Lee, Jonathan K.; Roemer, Lizabeth; Orsillo, Susan M.

2013-01-01

A growing body of research suggests that mindfulness- and acceptance-based principles can increase efforts aimed at reducing human suffering and increasing quality of life. A critical step in the development and evaluation of these new approaches to treatment is to determine the acceptability and efficacy of these treatments for clients from…

Cyber Security Assessment Report: Adventium Labs

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

2007-12-31

Major control system components often have life spans of 15-20 years. Many systems in our Nation's critical infrastructure were installed before the Internet became a reality and security was a concern. Consequently, control systems are generally insecure. Security is now being included in the development of new control system devices; however, legacy control systems remain vulnerable. Most efforts to secure control systems are aimed at protecting network borers, but if an intruder gets inside the network these systems are vulnerable to a cyber attack.

History, Current Situation, and Future Development of Endoscopic Neurosurgery in China.

PubMed

Li, Chuzhong; Zhu, Haibo; Zong, Xuyi; Wang, Xinsheng; Gui, Songbai; Zhao, Peng; Zhang, Yazhuo

2018-02-01

During the past few decades, Chinese endoscopic neurosurgery has rapidly developed in synchrony with the rest of the world. The aim of this article is to review the development of Chinese endoscopic neurosurgery, including its birth, growth, current situation, and prospects. The history of Chinese endoscopic neurosurgery development can be divided into 3 stages: cognition and initial stage (1964-1995), exploration and maturity stage (1995-2006), and rapid development and promotion stage (2006-present). In the first stage, we mainly began to become aware of endoscopic neurosurgery from the translation and review of literature. In the mid to late 1990s, Chinese neurosurgery pioneers began using neuroendoscopic techniques. In the following decade, many leading neurosurgeons made persistent efforts to push the development of Chinese endoscopic neurosurgery forward, focusing on advocating for and promoting and popularizing neuroendoscopic technology. In the rapid development and promotion stage, many representative national and regional neurosurgical centers became skilled and efficient in the application of neuroendoscopic technology and became new advocates of the technology. The number of cases, level of technology, and treatment effectiveness are gradually nearing international standards. However, future development requires promotion of balanced development to decrease regional disparities, further strengthen international exchanges, follow the latest developments, and constantly innovate for continuous improvement. Following the dramatic efforts of several pioneers, development of Chinese endoscopic neurosurgery has been considerable, and it has become an important component of neurosurgery worldwide. Copyright © 2017 Elsevier Inc. All rights reserved.

In the national interest: the PCSD puts population growth back on the agenda.

PubMed

Dixon, B

1995-01-01

In 1972, President Nixon launched the Rockefeller Commission on Population Growth and the American Future. The US population has grown by more than 50 million people since 1972. In 1995, a report by the President's Council on Sustainable Development (PCSD) states that failure on the part of the US to stabilize its population will jeopardize any effort to achieve sustainable development. As a follow-up to the Earth Summit, President Clinton established the PCSD in 1993 to identify ways to encourage sustainable development in the US. The Council has 25 members representing government, business, and public interest organizations and has 8 critical issues task forces, including Energy, Transportation, Sustainable Community, Education and Outreach, Natural Resources, Eco Efficiency and Sustainable Agriculture. Timothy Wirth, Under Secretary of State for Global Affairs, spearheaded efforts to create a task force on the twin issues of population and consumption. The Population and Consumption Task Force, which began its official discussions in the spring of 1994, aimed to solicit public comment on critical population-related issues. These meetings sought both general public and expert participation on subjects such as teen pregnancy, resource use, and economic indicators. Among these recommendations are improving access to family planning services for all Americans; focusing on special efforts to reduce teen pregnancy and childbearing; improving external factors such as poverty and a lack of economic opportunities for girls and women; and reducing immigration to the US. A combination of actions are needed, including a tax shift from labor and earnings to natural resource use; development of environmentally sound technologies; and public understanding of the importance of sustainable life style and consumption choices. Individual and community action is crucial since the current Congress is unlikely to adopt policies to promote sustainable development without significant public pressure.

[Role of researchers and employees of the Military Medical Academy in development of the system of military medical supply].

PubMed

Miroshnichenko, Iu V; Kononov, V N; Perfil'ev, A B

2013-12-01

The Military Medical Academy has been solving theoretical and practical issues, concerning development of military medical supply, for 215 years. At different time periods and according to needs of military medicine and pharmacy researches and employees of the Academy aimed efforts to: development of the theory and practice of medical supply organization, regulatory basis of the system of medical supply, development of new samples of medical equipment, development of medicine manufacturing technologies and methods of quality control, researches in the area of medicine radiochemistry, forensic chemistry and toxicology, herbal and mineral water analysis and etc. At the present time there are the following education programs at the Academy: "Pharmacy", magister program "Management of medical supply", program for resident physicians "Management and economics of pharmacy".

Quality measurement in diabetes care.

PubMed

Leas, Brian F; Berman, Bettina; Kash, Kathryn M; Crawford, Albert G; Toner, Richard W; Goldfarb, Neil I; Nash, David B

2009-10-01

This study aimed to evaluate diabetes quality measurement efforts, assess their strengths and areas for improvement, and identify gaps not adequately addressed by these measures. We conducted an environmental scan of diabetes quality measures, focusing on metrics included in the National Quality Measures Clearinghouse or promulgated by leading measurement organizations. Key informant interviews were also completed with thought leaders who develop, promote, and use quality measures. The environmental scan identified 146 distinct measures spanning 31 clinical processes or outcomes. This suggests a measurement system that is both redundant and inconsistent, with many different measures assessing the same clinical indicators. Interviewees believe that current diabetes measurement efforts are excessively broad and complex and expressed a need for better harmonization of these measures. Several gaps were also found, including a lack of measures focusing on population health, structural elements of health care, and prevention of diabetes.

The Application of Modeling and Simulation to the Behavioral Deficit of Autism

NASA Technical Reports Server (NTRS)

Anton, John J.

2010-01-01

This abstract describes a research effort to apply technological advances in virtual reality simulation and computer-based games to create behavioral modification programs for individuals with Autism Spectrum Disorder (ASD). The research investigates virtual social skills training within a 3D game environment to diminish the impact of ASD social impairments and to increase learning capacity for optimal intellectual capability. Individuals with autism will encounter prototypical social contexts via computer interface and will interact with 3D avatars with predefined roles within a game-like environment. Incremental learning objectives will combine to form a collaborative social environment. A secondary goal of the effort is to begin the research and development of virtual reality exercises aimed at triggering the release of neurotransmitters to promote critical aspects of synaptic maturation at an early age to change the course of the disease.

Distracted driving: prevalence, problems, and prevention.

PubMed

Overton, Tiffany L; Rives, Terry E; Hecht, Carrie; Shafi, Shahid; Gandhi, Rajesh R

2015-01-01

While the number of motor vehicle crashes has declined over the years, crashes resulting from distracted driving are increasing in the United States resulting in significant morbidity and mortality. The national public seems to be aware of the dangers associated with using technology while driving, but continues to engage in this dangerous behaviour, and may be unaware of or underestimate the impact of cell phone use on their own driving performance. Problems associated with distracted driving are not limited to novice or teenage drivers; multifaceted universal prevention efforts aimed at impacting large segments of the population may have the greatest impact. Legislation limiting drivers' cell phone use has had little impact, possibly due to low regulation and enforcement. Behaviour change programmes, improved vehicle safety, and public awareness campaigns have been developed as potential preventive efforts to reduce accidents caused by distracted drivers.

Taking aim at novel vaccines market.

PubMed

Awasthi, Sita

2009-10-01

The World Vaccine Congress Washington 2009 was held in Chantilly, VA USA April 2O -23rd. The Vaccine congress attracted over 400 participants from across the world, including leading vaccine manufacturers, biotechs, governmental agencies, NGOs, research and academic institutes, venture capital and legal firms, contract service and equipment manufacturers. The speakers covered a wide range of topics, including the role of government and regulatory agencies, funding availability, research and development, manufacturing, packaging and post vaccine evaluations. Past vaccine development efforts have historically focused on infectious diseases. With advancements in the field of immunology, molecular biology and vaccinology, the vaccine field has begun moving in new directions. "Taking aim at novel vaccines market" session chaired by Dr. Una Ryan, Chief Executive Officer of Waltham Technologies, was focused on traditional approaches to novel targets (nosocomial infections), novel approaches to traditional targets (flu and rabies), novel approaches to novel targets (Type 1 diabetes, multiple sclerosis and smoking) and vaccines for developing markets (TB, malaria, rabies). The importance of collaborations among academic institutions, industries, and philanthropic foundations for developing markets was also emphasized.

Progress of MCT Detector Technology at AIM Towards Smaller Pitch and Lower Dark Current

NASA Astrophysics Data System (ADS)

Eich, D.; Schirmacher, W.; Hanna, S.; Mahlein, K. M.; Fries, P.; Figgemeier, H.

2017-09-01

We present our latest results on cooled p-on- n planar mercury cadmium telluride (MCT) photodiode technology. Along with a reduction in dark current for raising the operating temperature ( T op), AIM INFRAROT-MODULE GmbH (AIM) has devoted its development efforts to shrinking the pixel size. Both are essential requirements to meet the market demands for reduced size, weight and power and high-operating temperature applications. Detectors based on the p-on- n technology developed at AIM now span the spectrum from the mid-wavelength infrared (MWIR) to the very long wavelength infrared (VLWIR) with cut-off wavelengths from 5 μm to about 13.5 μm at 80 K. The development of the p-on- n technology for VLWIR as well as for MWIR is mainly implemented in a planar photodetector design with a 20- μm pixel pitch. For the VLWIR, dark currents significantly reduced as compared to `Tennant's Rule 07' are demonstrated for operating temperatures between 30 K and 100 K. This allows for the same dark current performance at a 20 K higher operating temperature than with previous AIM technology. For MWIR detectors with a 20- μm pitch, noise equivalent temperature differences of less than 30 mK are obtained up to 170 K. This technology has been transferred to our small pixel pitch high resolution (XGA) MWIR detector with 1024 × 768 pixels at a 10- μm pitch. Excellent performance at an operating temperature of 160 K is demonstrated.

Bringing Technology into High School Physics Classrooms

NASA Astrophysics Data System (ADS)

Zettili, Nouredine

2005-04-01

In an effort to help high school physics teachers bring technology into their classrooms, we at JSU have been offering professional development to secondary education teachers. This effort is part of Project IMPACTSEED (IMproving Physics And Chemistry Teaching in SEcondary Education), a No-Child Left Behind (NCLB) grant funded by the Alabama Commission on Higher Education, serving high school physics teachers in Northeast Alabama. This project is motivated by a major pressing local need: A large number of high school physics teachers teach out of field. To achieve IMPACTSEED's goals, we have forged a functional collaboration with school districts from about ten counties. This collaboration is aimed at achieving a double aim: (a) to make physics and chemistry understandable and fun to learn within a hands-on, inquiry-based setting; (b) to overcome the fear- factor for physics and chemistry among students. Through a two-week long summer institute, a series of weekend technology workshops, and onsite support, we have been providing year-round support to the physics/chemistry teachers in this area. This outreach initiative has helped provide our students with a physics/chemistry education that enjoys a great deal of continuity and consistency from high school to college.

Making the State of the Art the Classroom Benchmark: A Climate Change Curriculum Based on Synthesis Science

NASA Astrophysics Data System (ADS)

Nicholas, K. A.

2014-12-01

A hallmark of science in the Anthropocene is the increasing use of synthesis efforts to distill ever-growing data into the best available scientific knowledge. Thousands of scientists contribute substantial amounts of time towards these efforts, with the aim of producing authoritative work as a basis for informing both further research priorities and policy decisions. Organizations such as the IPCC are increasing their efforts to disseminate their scientific findings to broader audiences, for example, using text and video summaries targeted for policymakers. However, the results of such synthesis efforts have rarely been disseminated further back in the pipeline, in the classrooms where scientific literacy is shaped. Here, I will describe an emerging initiative to develop a program to translate state-of-the-art scientific synthesis findings into a modular, flexible climate change curriculum. This initiative is envisioned to compliment rather than compete with existing curriculum development efforts. Examples from innovation labs in healthcare delivery and other fields will be used to demonstrate a model for how a small, interdisciplinary team of early-career experts can use their content and pedagogical knowledge to transform synthesis results into ready-to-use teaching materials. The benefits of such a curriculum include improved student learning through constructive alignment of thoughtfully designed teaching and learning activities and assessment activities to promote intended learning outcomes, as well as the real-world illustration of the method of scientific inquiry applied to socially relevant problems. The curriculum can also improve teaching experiences through increased efficiency in course preparation, and in sharing best practices with participating colleagues. Initial scoping will examine the needs of university teachers of climate change courses as the constituents of this curriculum, and possible support models to mainstream such efforts. Ultimately, using scientific syntheses as the basis for university curricula would help close the gap between research and classroom learning, promote increased scientific understanding, and help ensure that the resources devoted to scientific synthesis efforts are translated to broader benefits for society.

The Brazilian version of the effort-reward imbalance questionnaire to assess job stress.

PubMed

Chor, Dóra; Werneck, Guilherme Loureiro; Faerstein, Eduardo; Alves, Márcia Guimarães de Mello; Rotenberg, Lúcia

2008-01-01

The effort-reward imbalance (ERI) model has been used to assess the health impact of job stress. We aimed at describing the cross-cultural adaptation of the ERI questionnaire into Portuguese and some psychometric properties, in particular internal consistency, test-retest reliability, and factorial structure. We developed a Brazilian version of the ERI using a back-translation method and tested its reliability. The test-retest reliability study was conducted with 111 health workers and University staff. The current analyses are based on 89 participants, after exclusion of those with missing data. Reproducibility (interclass correlation coefficients) for the "effort", "'reward", and "'overcommitment"' dimensions of the scale was estimated at 0.76, 0.86, and 0.78, respectively. Internal consistency (Cronbach's alpha) estimates for these same dimensions were 0.68, 0.78, and 0.78, respectively. The exploratory factorial structure was fairly consistent with the model's theoretical components. We conclude that the results of this study represent the first evidence in favor of the application of the Brazilian Portuguese version of the ERI scale in health research in populations with similar socioeconomic characteristics.

Roles for specialty societies and vascular surgeons in accountable care organizations.

PubMed

Goodney, Philip P; Fisher, Elliott S; Cambria, Richard P

2012-03-01

With the passage of the Affordable Care Act, accountable care organizations (ACOs) represent a new paradigm in healthcare payment reform. Designed to limit growth in spending while preserving quality, these organizations aim to incant physicians to lower costs by returning a portion of the savings realized by cost-effective, evidence-based care back to the ACO. In this review, first, we will explore the development of ACOs within the context of prior attempts to control Medicare spending, such as the sustainable growth rate and managed care organizations. Second, we describe the evolution of ACOs, the demonstration projects that established their feasibility, and their current organizational structure. Third, because quality metrics are central to the use and implementation of ACOs, we describe current efforts to design, collect, and interpret quality metrics in vascular surgery. And fourth, because a "seat at the table" will be an important key to success for vascular surgeons in these efforts, we discuss how vascular surgeons can participate and lead efforts within ACOs. Copyright © 2012 Society for Vascular Surgery. Published by Mosby, Inc. All rights reserved.

A Multi-targeted Approach to Suppress Tumor-Promoting Inflammation

PubMed Central

Samadi, Abbas K.; Georgakilas, Alexandros G.; Amedei, Amedeo; Amin, Amr; Bishayee, Anupam; Lokeshwar, Bal L.; Grue, Brendan; Panis, Carolina; Boosani, Chandra S.; Poudyal, Deepak; Stafforini, Diana M.; Bhakta, Dipita; Niccolai, Elena; Guha, Gunjan; Rupasinghe, H.P. Vasantha; Fujii, Hiromasa; Honoki, Kanya; Mehta, Kapil; Aquilano, Katia; Lowe, Leroy; Hofseth, Lorne J.; Ricciardiello, Luigi; Ciriolo, Maria Rosa; Singh, Neetu; Whelan, Richard L.; Chaturvedi, Rupesh; Ashraf, S. Salman; Kumara, HMC Shantha; Nowsheen, Somaira; Mohammed, Sulma I.; Helferich, William G.; Yang, Xujuan

2015-01-01

Cancers harbor significant genetic heterogeneity and patterns of relapse following many therapies are due to evolved resistance to treatment. While efforts have been made to combine targeted therapies, significant levels of toxicity have stymied efforts to effectively treat cancer with multi-drug combinations using currently approved therapeutics. We discuss the relationship between tumor-promoting inflammation and cancer as part of a larger effort to develop a broad-spectrum therapeutic approach aimed at a wide range of targets to address this heterogeneity. Specifically, macrophage migration inhibitory factor, cyclooxygenase-2, transcription factor nuclear factor-kappaB, tumor necrosis factor alpha, inducible nitric oxide synthase, protein kinase B, and CXC chemokines are reviewed as important antiinflammatory targets while curcumin, resveratrol, epigallocatechin gallate, genistein, lycopene, and anthocyanins are reviewed as low-cost, low toxicity means by which these targets might all be reached simultaneously. Future translational work will need to assess the resulting synergies of rationally designed antiinflammatory mixtures (employing low-toxicity constituents), and then combine this with similar approaches targeting the most important pathways across the range of cancer hallmark phenotypes. PMID:25951989

Temporal Allocation of Foraging Effort in Female Australian Fur Seals (Arctocephalus pusillus doriferus)

PubMed Central

Hoskins, Andrew J.; Arnould, John P. Y.

2013-01-01

Across an individual's life, foraging decisions will be affected by multiple intrinsic and extrinsic drivers that act at differing timescales. This study aimed to assess how female Australian fur seals allocated foraging effort and the behavioural changes used to achieve this at three temporal scales: within a day, across a foraging trip and across the final six months of the lactation period. Foraging effort peaked during daylight hours (57% of time diving) with lulls in activity just prior to and after daylight. Dive duration reduced across the day (196 s to 168 s) but this was compensated for by an increase in the vertical travel rate (1500–1600 m·h−1) and a reduction in postdive duration (111–90 s). This suggests physiological constraints (digestive costs) or prey availability may be limiting mean dive durations as a day progresses. During short trips (<2.9 d), effort remained steady at 55% of time diving, whereas, on long trips (>2.9 d) effort increased up to 2–3 d and then decreased. Dive duration decreased at the same rate in short and long trips, respectively, before stabilising (long trips) between 4–5 d. Suggesting that the same processes (digestive costs or prey availability) working at the daily scale may also be present across a trip. Across the lactation period, foraging effort, dive duration and vertical travel rate increased until August, before beginning to decrease. This suggests that as the nutritional demands of the suckling pup and developing foetus increase, female effort increases to accommodate this, providing insight into the potential constraints of maternal investment in this species. PMID:24244511

A knowledge platform to inform on the effects of trawling on benthic communities

NASA Astrophysics Data System (ADS)

Muntadas, Alba; Lample, Michel; Demestre, Montserrat; Ballé-Béganton, Johanna; de Juan, Silvia; Maynou, Francesc; Bailly, Denis

2018-02-01

For a successful implementation of an Ecosystem Approach to Fisheries (EAF) management, it is necessary that all stakeholders involved in fisheries management are aware of the implications of fishing impacts on ecosystems and agree with the adopted measures to mitigate these impacts. In this context, there is a need for tools to share knowledge on the ecosystem effects of fisheries among these stakeholders. When managing bottom trawl fisheries under an EAF framework, one of the main concerns is the direct and indirect consequences of trawling impacts on benthic ecosystems. We developed a platform using the ExtendSim® software with a user-friendly interface that combines a simulation model based on existing knowledge, data collection and representation of predicted trawling impacts on the seabed. The platform aims to be a deliberation support tool for fisheries' stakeholders and, simultaneously, raise public awareness of the need for good benthic community knowledge to appropriately inform EAF management plans. The simulation procedure assumes that trawling affects benthic communities with an intensity that depends on the level of fishing effort exerted on benthic communities and on the habitat characteristics (i.e. sediment grain size). Data to build the simulation comes from epifaunal samples from 18 study sites located in Mediterranean continental shelves subjected to different levels of fishing effort. In this work, we present the simulation outputs of a 50% fishing effort increase (and decrease) in four of the study sites which cover different habitats and different levels of fishing effort. We discuss the platform strengths and weaknesses and potential future developments.

Binaural fusion and listening effort in children who use bilateral cochlear implants: a psychoacoustic and pupillometric study.

PubMed

Steel, Morrison M; Papsin, Blake C; Gordon, Karen A

2015-01-01

Bilateral cochlear implants aim to provide hearing to both ears for children who are deaf and promote binaural/spatial hearing. Benefits are limited by mismatched devices and unilaterally-driven development which could compromise the normal integration of left and right ear input. We thus asked whether children hear a fused image (ie. 1 vs 2 sounds) from their bilateral implants and if this "binaural fusion" reduces listening effort. Binaural fusion was assessed by asking 25 deaf children with cochlear implants and 24 peers with normal hearing whether they heard one or two sounds when listening to bilaterally presented acoustic click-trains/electric pulses (250 Hz trains of 36 ms presented at 1 Hz). Reaction times and pupillary changes were recorded simultaneously to measure listening effort. Bilaterally implanted children heard one image of bilateral input less frequently than normal hearing peers, particularly when intensity levels on each side were balanced. Binaural fusion declined as brainstem asymmetries increased and age at implantation decreased. Children implanted later had access to acoustic input prior to implantation due to progressive deterioration of hearing. Increases in both pupil diameter and reaction time occurred as perception of binaural fusion decreased. Results indicate that, without binaural level cues, children have difficulty fusing input from their bilateral implants to perceive one sound which costs them increased listening effort. Brainstem asymmetries exacerbate this issue. By contrast, later implantation, reflecting longer access to bilateral acoustic hearing, may have supported development of auditory pathways underlying binaural fusion. Improved integration of bilateral cochlear implant signals for children is required to improve their binaural hearing.

Development of Bone Remodeling Model for Spaceflight Bone Physiology Analysis

NASA Technical Reports Server (NTRS)

Pennline, James A.; Werner, Christopher R.; Lewandowski, Beth; Thompson, Bill; Sibonga, Jean; Mulugeta, Lealem

2015-01-01

Current spaceflight exercise countermeasures do not eliminate bone loss. Astronauts lose bone mass at a rate of 1-2% a month (Lang et al. 2004, Buckey 2006, LeBlanc et al. 2007). This may lead to early onset osteoporosis and place the astronauts at greater risk of fracture later in their lives. NASA seeks to improve understanding of the mechanisms of bone remodeling and demineralization in 1g in order to appropriately quantify long term risks to astronauts and improve countermeasures. NASA's Digital Astronaut Project (DAP) is working with NASA's bone discipline to develop a validated computational model to augment research efforts aimed at achieving this goal.

Development of a protective decorative fire resistant low smoke emitting, thermally stable coating material

NASA Technical Reports Server (NTRS)

1976-01-01

The development of suitable electrocoatings and subsequent application to nonconductive substrates are discussed. Substrates investigated were plastics or resin-treated materials such as FX-resin (phenolic-type resin) impregnated fiberglass mat, polyphenylene sulfide, polyether sulfone and polyimide-impregnated unidirectional fiberglass. Efforts were aimed at formulating a fire-resistant, low smoke emitting, thermally stable, easily cleaned coating material. The coating is to be used for covering substrate panels, such as aluminum, silicate foam, polymeric structural entities, etc., all of which are applied in the aircraft cabin interior and thus subject to the spillages, scuffing, spotting and the general contaminants which prevail in aircraft passenger compartments.

The road to worldwide sexuality education.

PubMed

Edwards, M

1997-01-01

The articles in this "SIECUS Report" document the organization's involvement in the development of sexuality education programs around the world. Topics covered by the articles in this issue include efforts by the Bolivian Government to increase understanding and acceptance of family planning methods, work with the Soros Foundation to train teachers to teach health education, a sexuality education pilot project in Russia, development of a culturally sensitive sex education program in Indonesia, and life education for youth in India. In the year ahead, SIECUS will implement country-specific programs in Nigeria, Swaziland, Russia, and India aimed at establishing frameworks for reproductive health, family planning, acquired immunodeficiency syndrome prevention, and population education programs.

Study on Collaborative SCM of Construction Enterprises Based on Information-Sharing

NASA Astrophysics Data System (ADS)

Wang, Lianyue

Economic globalization and the integration process has led to competition among construction enterprises become increasingly fierce, which are adjusting their development strategies and efforts to seek for the knowledge economy and network environment to promote enterprise survival and development, enhancing the competitiveness of enterprises in the new business management models and ideas. This paper first discussed the concept of the supply chain collaboration of the construction enterprise and constituted a information management platform of the general contracting project. At last, the paper puts forward tactics which aims at helping construction enterprises realize supply chain collaboration and enhance the competitiveness of enterprises.

Automation and Robotics for Human Mars Exploration (AROMA)

NASA Technical Reports Server (NTRS)

Hofmann, Peter; von Richter, Andreas

2003-01-01

Automation and Robotics (A&R) systems are a key technology for Mars exploration. All over the world initiatives in this field aim at developing new A&R systems and technologies for planetary surface exploration. From December 2000 to February 2002 Kayser-Threde GmbH, Munich, Germany lead a study called AROMA (Automation and Robotics for Human Mars Exploration) under ESA contract in order to define a reference architecture of A&R elements in support of a human Mars exploration program. One of the goals of this effort is to initiate new developments and to maintain the competitiveness of European industry within this field. c2003 Published by Elsevier Science Ltd.

Fire Island National Seashore

USGS Publications Warehouse

Brock, John C.; Wright, C. Wayne; Patterson, Matt; Nayagandhi, Amar; Patterson, Judd

2007-01-01

These lidar-derived topographic maps were produced as a collaborative effort between the U.S. Geological Survey (USGS) Coastal and Marine Geology Program, the National Park Service (NPS), Northeast Coastal and Barrier Network, Inventory and Monitoring Program, and the National Aeronautics and Space Administration (NASA) Wallops Flight Facility. The aims of the partnership that created this product are to develop advanced survey techniques for mapping barrier island geomorphology and habitats, and to enable the monitoring of ecological and geological change within National Seashores. This product is based on data from an innovative airborne lidar instrument under development at the NASA Wallops Flight Facility, the NASA Experimental Advanced Airborne Research Lidar (EAARL).

Genetic design automation: engineering fantasy or scientific renewal?

PubMed

Lux, Matthew W; Bramlett, Brian W; Ball, David A; Peccoud, Jean

2012-02-01

The aim of synthetic biology is to make genetic systems more amenable to engineering, which has naturally led to the development of computer-aided design (CAD) tools. Experimentalists still primarily rely on project-specific ad hoc workflows instead of domain-specific tools, which suggests that CAD tools are lagging behind the front line of the field. Here, we discuss the scientific hurdles that have limited the productivity gains anticipated from existing tools. We argue that the real value of efforts to develop CAD tools is the formalization of genetic design rules that determine the complex relationships between genotype and phenotype. Copyright © 2011 Elsevier Ltd. All rights reserved.

Automation and Robotics for Human Mars Exploration (AROMA).

PubMed

Hofmann, Peter; von Richter, Andreas

2003-01-01

Automation and Robotics (A&R) systems are a key technology for Mars exploration. All over the world initiatives in this field aim at developing new A&R systems and technologies for planetary surface exploration. From December 2000 to February 2002 Kayser-Threde GmbH, Munich, Germany lead a study called AROMA (Automation and Robotics for Human Mars Exploration) under ESA contract in order to define a reference architecture of A&R elements in support of a human Mars exploration program. One of the goals of this effort is to initiate new developments and to maintain the competitiveness of European industry within this field. c2003 Published by Elsevier Science Ltd.

The effects of work alienation on organisational commitment, work effort and work-to-family enrichment.

PubMed

Tummers, Lars G; Den Dulk, Laura

2013-09-01

The aim of this study was to analyse the effects of work alienation on organisational commitment, work effort and work-to-family enrichment. There is substantial research on the effects of work alienation on passive job performance, such as organisational commitment. However, studies analysing work alienation on active performance, such as work effort, and outside work, such as work-to-family enrichment, are scarce. Two dimensions of work alienation are considered: powerlessness and meaninglessness. Hypotheses are tested using surveys collected among a national sample of midwives in the Netherlands (respondents: 790, response rate 61%). the findings indicate that work alienation (powerlessness and meaninglessness) influence organisational commitment, work effort and--to a lesser extent--work-to-family enrichment. High work meaninglessness, in particular, has negative effects on these outcomes. When people feel that they have no influence in their work (hence, when they feel 'powerless') and especially when the feel that their work is not worthwhile (when they feel 'meaningless') this has substantial negative effects. Managers should increase the meaningfulness that people attach to their work, thereby maintaining a high-quality workforce. Possible strategies include: (1) improving person-job fit, (2) developing high-quality relationships, (3) better communicating the results people help to deliver. © 2013 John Wiley & Sons Ltd.

Targeting women or transforming institutions? Policy lessons from NGO anti-poverty efforts.

PubMed

Kabeer, N

1995-05-01

Some research has found that the extent of gender-based discrimination in market-based institutions and unfair advantages within domestic and market institutions meant women were less successful in translating education and work into income and purchasing power. Anti-poverty programs functioned without specifically addressing the implications for women and children. Women-in-development efforts attempted to compensate for prior deficiencies by promotion of income generation schemes for women. In this article, the suggestion is made for policy makers to design projects with goals, objectives, and strategies that are clear, consistent, and well-informed about gender. Efforts should be made to avoid debates about women-only versus integrated projects. The experiences of nongovernmental organizations (NGOs) in the South Asian context offer lessons in good policy efforts to address all forms of marginalization. The definition of women's needs must be provided by women themselves; openness and flexibility are recommended. Participatory approaches serve the aims of needs identification, involvement in democratic processes, and awareness of constraints on women's use of resources. In credit lending, constraints were overcome by compensating for the absence of material collateral, guaranteeing physical access, simplifying procedures, and subsidizing access rather than interest rates. Underlying structural conditions that reinforce inequalities by gender are in need of change. Empowerment of women would assure that marginalization would not occur.

Probing sunspots with two-skip time-distance helioseismology

NASA Astrophysics Data System (ADS)

Duvall, Thomas L., Jr.; Cally, Paul S.; Przybylski, Damien; Nagashima, Kaori; Gizon, Laurent

2018-06-01

Context. Previous helioseismology of sunspots has been sensitive to both the structural and magnetic aspects of sunspot structure. Aims: We aim to develop a technique that is insensitive to the magnetic component so the two aspects can be more readily separated. Methods: We study waves reflected almost vertically from the underside of a sunspot. Time-distance helioseismology was used to measure travel times for the waves. Ray theory and a detailed sunspot model were used to calculate travel times for comparison. Results: It is shown that these large distance waves are insensitive to the magnetic field in the sunspot. The largest travel time differences for any solar phenomena are observed. Conclusions: With sufficient modeling effort, these should lead to better understanding of sunspot structure.

Health Disparities in Women

PubMed Central

Hornbuckle, Lyndsey M; Amutah-Onukagha, Ndidiamaka; Bryan, Alicia; Skidmore Edwards, Elizabeth; Madzima, Takudzwa; Massey, Kelly; May, Linda; Robinson, Leah E

2017-01-01

AIMS AND SCOPE Clinical Medicine Insights: Women’s Health is an international, open-access, peer-reviewed journal which considers manuscripts on all aspects of the diagnosis, management, and prevention of disorders specific to women, in addition to related genetic, pathophysiological, and epidemiological topics. Clinical Medicine Insights: Women’s Health aims to provide researchers working in this complex, quickly developing field with online, open access to highly relevant scholarly articles by leading international researchers. In a field where the literature is ever-expanding, researchers increasingly need access to up-to-date, high-quality scholarly articles on areas of specific contemporary interest. This supplement is on Health Disparities in Women. This supplement aims to address this by presenting high-quality articles that allow readers to distinguish the signal from the noise. The editor in chief hopes that through this effort, practitioners and researchers will be aided in finding answers to some of the most complex and pressing issues of our time. PMID:28579867

Health Security and Risk Aversion.

PubMed

Herington, Jonathan

2016-09-01

Health security has become a popular way of justifying efforts to control catastrophic threats to public health. Unfortunately, there has been little analysis of the concept of health security, nor the relationship between health security and other potential aims of public health policy. In this paper I develop an account of health security as an aversion to risky policy options. I explore three reasons for thinking risk avoidance is a distinctly worthwhile aim of public health policy: (i) that security is intrinsically valuable, (ii) that it is necessary for social planning and (iii) that it is an appropriate response to decision-making in contexts of very limited information. Striking the right balance between securing and maximizing population health thus requires a substantive, and hitherto unrecognized, value judgment. Finally, I critically evaluate the current health security agenda in light of this new account of the concept and its relationship to the other aims of public health policy. © 2016 John Wiley & Sons Ltd.

Moving formal methods into practice. Verifying the FTPP Scoreboard: Results, phase 1

NASA Technical Reports Server (NTRS)

Srivas, Mandayam; Bickford, Mark

1992-01-01

This report documents the Phase 1 results of an effort aimed at formally verifying a key hardware component, called Scoreboard, of a Fault-Tolerant Parallel Processor (FTPP) being built at Charles Stark Draper Laboratory (CSDL). The Scoreboard is part of the FTPP virtual bus that guarantees reliable communication between processors in the presence of Byzantine faults in the system. The Scoreboard implements a piece of control logic that approves and validates a message before it can be transmitted. The goal of Phase 1 was to lay the foundation of the Scoreboard verification. A formal specification of the functional requirements and a high-level hardware design for the Scoreboard were developed. The hardware design was based on a preliminary Scoreboard design developed at CSDL. A main correctness theorem, from which the functional requirements can be established as corollaries, was proved for the Scoreboard design. The goal of Phase 2 is to verify the final detailed design of Scoreboard. This task is being conducted as part of a NASA-sponsored effort to explore integration of formal methods in the development cycle of current fault-tolerant architectures being built in the aerospace industry.

All About EVE: Education and Public Outreach for the Extreme Ultraviolet Variability Experiment (EVE) of the NASA Solar Dynamic Observatory

NASA Astrophysics Data System (ADS)

Eparvier, F. G.; McCaffrey, M. S.; Buhr, S. M.

2008-12-01

With the aim of meeting NASA goals for education and public outreach as well as support education reform efforts including the National Science Education Standards, a suite of education materials and strategies have been developed by the Cooperative Institute for Environmental Sciences (CIRES) with the Laboratory for Atmospheric and Space Physics (LASP) at the University of Colorado for the Extreme Ultraviolet Variability Experiment (EVE), which is an instrument aboard the Solar Dynamic Observatory. This paper will examine the education materials that have been developed for teachers in the classroom and scientists who are conducting outreach, including handouts, a website on space weather for teachers, a slideshow presentation about the overall Solar Dynamic Observatory mission, and a DVD with videos explaining the construction and goals of the EVE instrument, a tour of LASP, and an overview of space science careers. The results and potential transferability of a pilot project developed through this effort that engaged English Second Language learners in a semester-long course on space weather that incorporated the used of a Sudden Ionospheric Disturbance (SID) Monitor will be highlighted.

Antimalarial compounds in Phase II clinical development.

PubMed

Held, Jana; Jeyaraj, Sankarganesh; Kreidenweiss, Andrea

2015-03-01

Malaria is a major health problem in endemic countries and chemotherapy remains the most important tool in combating it. Treatment options are limited and essentially rely on a single drug class - the artemisinins. Efforts are ongoing to restrict the evolving threat of artemisinin resistance but declining sensitivity has been reported. Fueled by the ambitious aim of malaria eradication, novel antimalarial compounds, with improved properties, are now in the progressive phase of drug development. Herein, the authors describe antimalarial compounds currently in Phase II clinical development and present the results of these investigations. Thanks to recent efforts, a number of promising antimalarial compounds are now in the pipeline. First safety data have been generated for all of these candidates, although their efficacy as antimalarials is still unclear for most of them. Of particular note are KAE609, KAF156 and DSM265, which are of chemical scaffolds new to malaria chemotherapy and would truly diversify antimalarial options. Apart from SAR97276, which also has a novel chemical scaffold that has had its development stopped, all other compounds in the pipeline belong to already known substance classes, which have been chemically modified. At this moment in time, there is not one standout compound that will revolutionize malaria treatment but several compounds that will add to its control in the future.

The development and performance of smud grid-connected photovoltaic projects

DOE Office of Scientific and Technical Information (OSTI.GOV)

Osborn, D.E.; Collier, D.E.

1995-11-01

The utility grid-connected market has been identified as a key market to be developed to accelerate the commercialization of photovoltaics. The Sacramento Municipal Utility District (SMUD) has completed the first two years of a continuing commercialization effort based on two years of a continuing commercialization effort based on the sustained, orderly development of the grid-connected, utility PV market. This program is aimed at developing the experience needed to successfully integrate PV as distributed generation into the utility system and to stimulate the collaborative processes needed to accelerate the cost reductions necessary for PV to be cost-effective in these applications bymore » the year 2000. In the first two years, SMUD has installed over 240 residential and commercial building, grid-connected, rooftop, {open_quotes}PV Pioneer{close_quotes} systems totaling over 1MW of capacity and four substation sited, grid-support PV systems totaling 600 kW bringing the SMUD distributed PV power systems to over 3.7 MW. The 1995 SMUD PV Program will add another approximately 800 kW of PV systems to the District`s distributed PV power system. SMUD also established a partnership with its customers through the PV Pioneer {open_quotes}green pricing{close_quotes} program to advance PV commercialization.« less

IYA2009 Programs in Canada: The "Big Picture” In June, 2008

NASA Astrophysics Data System (ADS)

Hesser, James E.; Lane, D.; Langill, P. P. L.; Percy, J. R.; Canada Committee, IYA

2008-05-01

The Canadian partnership--Royal Astronomical Society of Canada (RASC), Fédération des astronomes amateurs du Québec (FAAQ) and Canadian Astronomical Society (CASCA)--is implementing elements designed to offer an engaging astronomy experience to every Canadian during 2009. Our goals for all themes envision creating long-lasting impacts, especially in the education and inspiration of youth. Wherever possible we seek to leverage and extend existing programs, and we aim to provide materials in both English and French. To make IYA2009 successful, both the RASC and FAAQ have committed significant funds over and above their extensive in-kind contributions of volunteer time. Through The Galileo Moment theme we aim to get more than one million Canadians to look through a telescope, or participate in cultural and outreach events that bring a strong sense of personal astronomical discovery. An Astronomy Kit of physical and virtual components is under development. A partnership led by Cape Breton University faculty proposes extensive participation by Canada's Aboriginal Communities, including a series of activities designed to bring elders and youth together. Reinvigoration of the RASC's long-standing efforts to create Dark Sky Preserves is another cross-cutting theme. Outreach programs of Canada's major Planetaria and Science Centres, a National Astronomy Lecture Series, as well as partnerships with Arts and Cultural Organizations, offer hopes of reaching both traditional and non-traditional audiences in fun, engaging ways. Individual volunteer efforts are emerging to implement From the Earth to the Universe astronomical image exhibits from material developed by both IAU and Canadian curatorial teams in high-traffic locales. Efforts are underway to secure commemorative stamps and coins, with recent encouraging news about the former. The Canadian Space Agency has agreed to launch in 2010 a CD/DVD with names of the Canadians who register their Galileo Moment experience. Fund raising is underway in earnest. See www.astronomy2009.ca for current information.

IYA2009 Programmes in Canada: The ``Big Picture'' in June 2008

NASA Astrophysics Data System (ADS)

Hesser, J. E.; Lane, D.; Langill, P. P.; Percy, J. R.

2008-11-01

The Canadian partnership---Royal Astronomical Society of Canada (RASC), Fédération des astronomes amateurs du Québec (FAAQ), and Canadian Astronomical Society (CASCA)---is implementing elements designed to offer an engaging astronomy experience to every Canadian during 2009. Our goals for all themes envision creating long-lasting impacts, especially in the education and inspiration of youth. Wherever possible we seek to leverage and extend existing programmes, and we aim to provide materials in both English and French. To make IYA2009 successful, both the RASC and FAAQ have committed significant funds over and above their extensive in-kind contributions of volunteer time. Through the `Galileo Moment' theme we aim to get more than one million Canadians to look through a telescope, or participate in cultural and outreach events that bring a strong sense of personal astronomical discovery. An Astronomy Kit of physical and/or virtual components is under development. A partnership led by Cape Breton University faculty proposes extensive participation by Canada's Aboriginal Communities, including a series of activities designed to bring elders and youth together. Reinvigoration of the RASC's long-standing efforts to create Dark Sky Preserves is another cross-cutting theme. Outreach programmes of Canada's major planetaria and science centres, a national astronomy lecture series, as well as partnerships with arts and cultural organizations, offer hopes of reaching both traditional and non-traditional audiences in fun, engaging ways. Individual volunteer efforts are emerging to implement in high-traffic locales From the Earth to the Universe astronomical image exhibits from material developed by both IAU and Canadian curatorial teams. Our proposal for commemorative stamps has been accepted, and efforts are underway to secure commemorative coins, as well. The Canadian Space Agency has agreed to launch in 2010 a DVD with names of the Canadians who register their Galileo Moment experience. Fund raising is underway in earnest. See http://www.astronomy2009.ca for current information.

Strength in Numbers: Opportunities for Enhancing the Development of Effective Treatments for Type 1 Diabetes-The TrialNet Experience.

PubMed

Greenbaum, Carla J; Speake, Cate; Krischer, Jeffrey; Buckner, Jane; Gottlieb, Peter A; Schatz, Desmond A; Herold, Kevan C; Atkinson, Mark A

2018-07-01

The early to mid-1980s were an inflection point in the history of type 1 diabetes research. Two landmark events occurred: the initiation of immune-based interventions seeking to prevent type 1 diabetes and the presentation of an innovative model describing the disorder's natural history. Both formed the basis for hundreds of subsequent studies designed to achieve a dramatic therapeutic goal-a means to prevent and/or reverse type 1 diabetes. However, the need to screen large numbers of individuals and prospectively monitor them using immunologic and metabolic tests for extended periods of time suggested such efforts would require a large collaborative network. Hence, the National Institutes of Health formed the landmark Diabetes Prevention Trial-Type 1 (DPT-1) in the mid-1990s, an effort that led to Type 1 Diabetes TrialNet. TrialNet studies have helped identify novel biomarkers; delineate type 1 diabetes progression, resulting in identification of highly predictable stages defined by the accumulation of autoantibodies (stage 1), dysglycemia (stage 2), and disease meeting clinical criteria for diagnosis (stage 3); and oversee numerous clinical trials aimed at preventing disease progression. Such efforts pave the way for stage-specific intervention trials with improved hope that a means to effectively disrupt the disorder's development will be identified. © 2018 by the American Diabetes Association.

A New Simulation Framework for the Electron-Ion Collider

NASA Astrophysics Data System (ADS)

Arrington, John

2017-09-01

Last year, a collaboration between Physics Division and High-Energy Physics at Argonne was formed to enable significantly broader contributions to the development of the Electron-Ion Collider. This includes efforts in accelerator R&D, theory, simulations, and detector R&D. I will give a brief overview of the status of these efforts, with emphasis on the aspects aimed at enabling the community to more easily become involved in evaluation of physics, detectors, and details of spectrometer designs. We have put together a new, easy-to-use simulation framework using flexible software tools. The goal is to enable detailed simulations to evaluate detector performance and compare detector designs. In addition, a common framework capable of providing detailed simulations of different spectrometer designs will allow for fully consistent evaluations of the physics reach of different spectrometer designs or detector systems for a variety of physics channels. In addition, new theory efforts will provide self-consistent models of GPDs (including QCD evolution) and TMDs in nucleons and light nuclei, as well as providing more detailed physics input for the evaluation of some new observables. This material is based upon work supported by Laboratory Directed Research and Development (LDRD) funding from Argonne National Laboratory, provided by the Director, Office of Science, of the U.S. Department of Energy under Contract DE-AC02-06CH11357.

Federal STEM Policy and Politics and Their Impact on Astronomy EPO: Reflections and Provocations

NASA Astrophysics Data System (ADS)

Schultz, G.; Storksdieck, M.; Canright, S.

2015-11-01

The federal government invests more than $3 billion each year across its various units in supporting STEM education and outreach. Efforts in recent years to understand and better coordinate these investments have resulted in considerable pushback, particularly those efforts that aimed at consolidation and elimination of programs deemed ineffective or duplicative. While initial plans to streamline federal STEM education were defeated, many agencies nonetheless saw cuts and elimination, and a high-level effort to coordinate STEM education at the cross-agency level is now gaining steam (CoSTEM: Committee on Science, Technology, Engineering, and Mathematics Education). What do all of these developments mean for education and public outreach in astronomy and related fields? How should this community operate within the opportunities and threats that CoSTEM might pose? Former director of the National Academy of Science's Board on Science Education, and now director of the Center for Research on Lifelong STEM Learning, Martin Storksdieck, reflected on past and recent developments from the perspective of a close observer, and from the perspective of someone who has been involved in astronomy education research and evaluation for nearly 20 years. Shelley Canright, Senior Advisor for Education Integration at the NASA Office of Education, shared her insights and perspectives with respect to CoSTEM and EPO, in particular from co-chairing the Federal Coordination in Science, Technology, Engineering, and Mathematics Education (FC-STEM) group.

Recent results from advanced research on space solar cells at NASA

NASA Technical Reports Server (NTRS)

Flood, Dennis J.

1990-01-01

The NASA program in space photovoltaic research and development encompasses a wide range of emerging options for future space power systems, and includes both cell and array technology development. The long range goals are to develop technology capable of achieving 300 W/kg for planar arrays, and 300 W/sq m for concentrator arrays. InP and GaAs planar and concentrator cell technologies are under investigation for their potential high efficiency and good radiation resistance. The Advanced Photovoltaic Solar Array (APSA) program is a near term effort aimed at demonstrating 130 W/kg beginning of life specific power using thin (62 pm) silicon cells. It is intended to be technology transparent to future high efficiency cells and provides the baseline for development of the 300 W/kg array.

NASA advanced space photovoltaic technology-status, potential and future mission applications

NASA Technical Reports Server (NTRS)

Flood, Dennis J.; Piszczor, Michael, Jr.; Stella, Paul M.; Bennett, Gary L.

1989-01-01

The NASA program in space photovoltaic research and development encompasses a wide range of emerging options for future space power systems, and includes both cell and array technology development. The long range goals are to develop technology capable of achieving 300 W/kg for planar arrays, and 300 W/sq m for concentrator arrays. InP and GaAs planar and concentrator cell technologies are under investigation for their potential high efficiency and good radiation resistance. The Advanced Photovoltaic Solar Array (APSA) program is a near term effort aimed at demonstrating 130 W/kg beginning of life specific power using thin (62 micrometer) silicon cells. It is intended to be technology transparent to future high efficiency cells and provides the baseline for development of the 300 W/kg array.

VESPA: Developing the Planetary Science Virtual Observatory in H2020

NASA Astrophysics Data System (ADS)

Erard, S.; Cecconi, B.; Le Sidaner, P.; Capria, T.; Rossi, A. P.; Schmitt, B.; André, N.; Vandaele, A.-C.; Scherf, M.; Hueso, R.; Maattanen, A.; Thuillot, W.; Achilleos, N.; Marmo, C.; Santolik, O.; Benson, K.; Bollard, Ph.

2015-10-01

The Europlanet H2020 programme will develop a research infrastructure in Horizon 2020. The programme includes a follow-on to the FP7 activity aimed at developing the Planetary Science Virtual Observatory (VO). This activity is called VESPA, which stands for Virtual European Solar and Planetary Access. Building on the IDIS activity of Europlanet FP7, VESPA will distribute more data, will improve the connected tools and infrastructure, and will help developing a community of both users and data providers. One goal of the Europlanet FP7 programme was to set the basis for a European Virtual Observatory in Planetary Science. A prototype has been set up during FP7, most of the activity being dedicated to the definition of standards to handle data in this field. The aim was to facilitate searches in big archives as well as sparse databases, to make on-line data access and visualization possible, and to allow small data providers to make their data available in an interoperable environment with minimum effort. This system makes intensive use of studies and developments led in Astronomy (IVOA), Solar Science (HELIO), plasma physics (SPASE), and space archive services (IPDA). It remains consistent with extensions of IVOA standards.

VESPA: developing the planetary science Virtual Observatory in H2020

NASA Astrophysics Data System (ADS)

Erard, Stéphane; Cecconi, Baptiste; Le Sidaner, Pierre; Capria, Teresa; Rossi, Angelo Pio

2016-04-01

The Europlanet H2020 programme will develop a research infrastructure in Horizon 2020. The programme includes a follow-on to the FP7 activity aimed at developing the Planetary Science Virtual Observatory (VO). This activity is called VESPA, which stands for Virtual European Solar and Planetary Access. Building on the IDIS activity of Europlanet FP7, VESPA will distribute more data, will improve the connected tools and infrastructure, and will help developing a community of both users and data providers. One goal of the Europlanet FP7 programme was to set the basis for a European Virtual Observatory in Planetary Science. A prototype has been set up during FP7, most of the activity being dedicated to the definition of standards to handle data in this field. The aim was to facilitate searches in big archives as well as sparse databases, to make on-line data access and visualization possible, and to allow small data providers to make their data available in an interoperable environment with minimum effort. This system makes intensive use of studies and developments led in Astronomy (IVOA), Solar Science (HELIO), plasma physics (SPASE), and space archive services (IPDA). It remains consistent with extensions of IVOA standards.

Motivations and Barriers for Policymakers to Developing State Adaptation Plans

NASA Astrophysics Data System (ADS)

Miller, R.; Sylak-Glassman, E.

2016-12-01

Current approaches for developing high-quality adaptation plan require significant resources. In recent years, communities have grown to embrace adaptive plans across multiple forms, including adaptive capacity assessments, resilience strategies, and vulnerability assessments. Across the United States, as of this writing, 14 states have established adaptation plans, with another 8 states having begun the process. Given the high resources requirements and increasing interest in the development of adaptation plans, we aim to examine patterns behind the establishment of resilience plans at the state level. We examine demographic, financial, political, and physical characteristics associated with different states in an effort to explore the reasoning behind investing in the development of adaptation plans. This analysis considers quantitative and qualitative factors, including recent elections for political parties, politicians' climate-related statements and campaign promises, demographics, budgets, and regional climate threats. The analysis aims to identify motivations for state leadership taking action to develop adaptation plans. Results from the analysis seek to identify the primary drivers and barriers associated with state-wide resilience planning. These results could inform the design of scientific communication tools or approaches to aid future adaptation responses to climate change.

Modern Vaccines/Adjuvants Formulation Session 6: Vaccine &Adjuvant Formulation & Production 15-17 May 2013, Lausanne, Switzerland.

PubMed

Fox, Christopher B

2013-09-01

The Modern Vaccines/Adjuvants Formulation meeting aims to fill a critical gap in current vaccine development efforts by bringing together formulation scientists and immunologists to emphasize the importance of rational formulation design in order to optimize vaccine and adjuvant bioactivity, safety, and manufacturability. Session 6 on Vaccine and Adjuvant Formulation and Production provided three examples of this theme, with speakers emphasizing the need for extensive physicochemical characterization of adjuvant-antigen interactions, the rational formulation design of a CD8+ T cell-inducing adjuvant based on immunological principles, and the development and production of a rabies vaccine by a developing country manufacturer. Throughout the session, the practical importance of sound formulation and manufacturing design accompanied by analytical characterization was highlighted.

Addressing medication nonadherence by mobile phone: development and delivery of tailored messages.

PubMed

Gatwood, Justin; Balkrishnan, Rajesh; Erickson, Steven R; An, Lawrence C; Piette, John D; Farris, Karen B

2014-01-01

Medication nonadherence remains a significant public health problem, and efforts to improve adherence have shown only limited impact. The tailoring of messages has become a popular method of developing communication to influence specific health-related behaviors but the development and impact of tailored text messages on medication use is poorly understood. The aim of this paper is to describe an approach to developing theory-based tailored messages for delivery via mobile phone to improve medication adherence among patients with diabetes. Kreuter's five-step tailoring process was followed to create tailored messages for mobile phone delivery. Two focus group sessions, using input from 11 people, and expert review of message content were used to adapt the survey instrument on which the messages were tailored and edit the developed messages for the target population. Following established tailoring methods a library of 168 theory-driven and 128 medication-specific tailored messages were developed and formatted for automated delivery to mobile phones. Concepts from the Health Belief Model and Self-Determination Theory were used to craft the messages and an algorithm was applied to determine the order and timing of messages with the aim of progressively influencing disease and treatment-related beliefs driving adherence to diabetes medication. The process described may be applied to future investigations aiming to improve medication adherence in patients with diabetes and the effectiveness of the current messages will be tested in a planned analysis. Copyright © 2014 Elsevier Inc. All rights reserved.

Mapping Fishing Effort through AIS Data

PubMed Central

Natale, Fabrizio; Gibin, Maurizio; Alessandrini, Alfredo; Vespe, Michele; Paulrud, Anton

2015-01-01

Several research initiatives have been undertaken to map fishing effort at high spatial resolution using the Vessel Monitoring System (VMS). An alternative to the VMS is represented by the Automatic Identification System (AIS), which in the EU became compulsory in May 2014 for all fishing vessels of length above 15 meters. The aim of this paper is to assess the uptake of the AIS in the EU fishing fleet and the feasibility of producing a map of fishing effort with high spatial and temporal resolution at European scale. After analysing a large AIS dataset for the period January-August 2014 and covering most of the EU waters, we show that AIS was adopted by around 75% of EU fishing vessels above 15 meters of length. Using the Swedish fleet as a case study, we developed a method to identify fishing activity based on the analysis of individual vessels’ speed profiles and produce a high resolution map of fishing effort based on AIS data. The method was validated using detailed logbook data and proved to be sufficiently accurate and computationally efficient to identify fishing grounds and effort in the case of trawlers, which represent the largest portion of the EU fishing fleet above 15 meters of length. Issues still to be addressed before extending the exercise to the entire EU fleet are the assessment of coverage levels of the AIS data for all EU waters and the identification of fishing activity in the case of vessels other than trawlers. PMID:26098430

Mapping Fishing Effort through AIS Data.

PubMed

Natale, Fabrizio; Gibin, Maurizio; Alessandrini, Alfredo; Vespe, Michele; Paulrud, Anton

2015-01-01

Several research initiatives have been undertaken to map fishing effort at high spatial resolution using the Vessel Monitoring System (VMS). An alternative to the VMS is represented by the Automatic Identification System (AIS), which in the EU became compulsory in May 2014 for all fishing vessels of length above 15 meters. The aim of this paper is to assess the uptake of the AIS in the EU fishing fleet and the feasibility of producing a map of fishing effort with high spatial and temporal resolution at European scale. After analysing a large AIS dataset for the period January-August 2014 and covering most of the EU waters, we show that AIS was adopted by around 75% of EU fishing vessels above 15 meters of length. Using the Swedish fleet as a case study, we developed a method to identify fishing activity based on the analysis of individual vessels' speed profiles and produce a high resolution map of fishing effort based on AIS data. The method was validated using detailed logbook data and proved to be sufficiently accurate and computationally efficient to identify fishing grounds and effort in the case of trawlers, which represent the largest portion of the EU fishing fleet above 15 meters of length. Issues still to be addressed before extending the exercise to the entire EU fleet are the assessment of coverage levels of the AIS data for all EU waters and the identification of fishing activity in the case of vessels other than trawlers.

Core Noise Reduction

NASA Technical Reports Server (NTRS)

Hultgren, Lennart S.

2011-01-01

This presentation is a technical summary of and outlook for NASA-internal and NASA-sponsored external research on core (combustor and turbine) noise funded by the Fundamental Aeronautics Program Subsonic Fixed Wing (SFW) Project. Sections of the presentation cover: the SFW system-level noise metrics for the 2015, 2020, and 2025 timeframes; turbofan design trends and their aeroacoustic implications; the emerging importance of core noise and its relevance to the SFW Reduce-Perceived-Noise Technical Challenge; and the current research activities in the core noise area. Recent work1 on the turbine-transmission loss of combustor noise is briefly described, two2,3 new NRA efforts in the core-noise area are outlined, and an effort to develop CMC-based acoustic liners for broadband noise reduction suitable for turbofan-core application is delineated. The NASA Fundamental Aeronautics Program has the principal objective of overcoming today's national challenges in air transportation. The reduction of aircraft noise is critical to enabling the anticipated large increase in future air traffic. The Subsonic Fixed Wing Project's Reduce-Perceived-Noise Technical Challenge aims to develop concepts and technologies to dramatically reduce the perceived aircraft noise outside of airport boundaries.

Combining computation and experiment to accelerate the discovery of new hydrogen storage materials

NASA Astrophysics Data System (ADS)

Siegel, Donald

2009-03-01

The potential of emerging technologies such as fuel cells (FCs) and photovoltaics for environmentally-benign power generation has sparked renewed interest in the development of novel materials for high density energy storage. For applications in the transportation sector, the demands placed upon energy storage media are especially stringent, as a potential replacement for fossil-fuel-powered internal combustion engines -- namely, the proton exchange membrane FC -- utilizes hydrogen as a fuel. Although hydrogen has about three times the energy density of gasoline by weight, its volumetric energy density (even at 700 bar) is roughly a factor of six smaller. Consequently, the safe and efficient storage of hydrogen has been identified as one of the key materials-based challenges to realizing a transition to FC vehicles. This talk will present an overview of recent efforts at Ford aimed at developing new materials for reversible, solid state hydrogen storage. A tight coupling between first-principles modeling and experiments has greatly accelerated our efforts, and several examples illustrating the benefits of this approach will be presented.

HIV reservoirs: the new frontier.

PubMed

Iglesias-Ussel, Maria D; Romerio, Fabio

2011-01-01

Current antiretroviral therapies suppress viremia to very low levels, but are ineffective in eliminating reservoirs of persistent HIV infection. Efforts toward the development of therapies aimed at HIV reservoirs are complicated by the evidence that HIV establishes persistent productive and nonproductive infection in a number of cell types and through a variety of mechanisms. Moreover, immunologically privileged sites such as the brain also act as HIV sanctuaries. To facilitate the advancement of our knowledge in this new area of research, in vitro models of HIV persistence in different cellular reservoirs have been developed, particularly in CD4+ T-cells that represent the largest pool of persistently infected cells in the body. Whereas each model presents clear advantages, they all share one common limitation: they are systems attempting to recapitulate extremely complex virus-cell interactions occurring in vivo, which we know very little about. Potentially conflicting results arising from different models may be difficult to interpret without validation with clinical samples. Addressing these issues, among others, merits careful consideration for the identification of valid targets and the design of effective strategies for therapy, which may increase the success of efforts toward HIV eradication.

Quantitative non-destructive testing

NASA Technical Reports Server (NTRS)

Welch, C. S.

1985-01-01

The work undertaken during this period included two primary efforts. The first is a continuation of theoretical development from the previous year of models and data analyses for NDE using the Optical Thermal Infra-Red Measurement System (OPTITHIRMS) system, which involves heat injection with a laser and observation of the resulting thermal pattern with an infrared imaging system. The second is an investigation into the use of the thermoelastic effect as an effective tool for NDE. As in the past, the effort is aimed towards NDE techniques applicable to composite materials in structural applications. The theoretical development described produced several models of temperature patterns over several geometries and material types. Agreement between model data and temperature observations was obtained. A model study with one of these models investigated some fundamental difficulties with the proposed method (the primitive equation method) for obtaining diffusivity values in plates of thickness and supplied guidelines for avoiding these difficulties. A wide range of computing speeds was found among the various models, with a one-dimensional model based on Laplace's integral solution being both very fast and very accurate.

Transforming exoelectrogens for biotechnology using synthetic biology.

PubMed

TerAvest, Michaela A; Ajo-Franklin, Caroline M

2016-04-01

Extracellular electron transfer pathways allow certain bacteria to transfer energy between intracellular chemical energy stores and extracellular solids through redox reactions. Microorganisms containing these pathways, exoelectrogens, are a critical part of microbial electrochemical technologies that aim to impact applications in bioenergy, biosensing, and biocomputing. However, there are not yet any examples of economically viable microbial electrochemical technologies due to the limitations of naturally occurring exoelectrogens. Here we first briefly summarize recent discoveries in understanding extracellular electron transfer pathways, then review in-depth the creation of customized and novel exoelectrogens for biotechnological applications. We analyze engineering efforts to increase current production in native exoelectrogens, which reveals that modulating certain processes within extracellular electron transfer are more effective than others. We also review efforts to create new exoelectrogens and highlight common challenges in this work. Lastly, we summarize work utilizing engineered exoelectrogens for biotechnological applications and the key obstacles to their future development. Fueled by the development of genetic tools, these approaches will continue to expand and genetically modified organisms will continue to improve the outlook for microbial electrochemical technologies. © 2015 Wiley Periodicals, Inc.

Harmonisation of ICD-11 and DSM-V: opportunities and challenges.

PubMed

First, Michael B

2009-11-01

Differences in the ICD-10 and DSM-IV definitions for the same disorder impede international communication and research efforts. The forthcoming parallel development of DSM-V and ICD-11 offers an opportunity to harmonise the two classifications. This paper aims to facilitate the harmonisation process by identifying diagnostic differences between the two systems. DSM-IV-TR criteria sets and the ICD-10 Diagnostic Criteria for Research were compared and categorised into those with identical definitions, those with conceptually based differences and those in which differences are not conceptually based and appear to be unintentional. Of the 176 criteria sets in both systems, only one, transient tic disorder, is identical. Twenty-one per cent had conceptually based differences and 78% had non-conceptually based differences. Harmonisation of criteria sets, especially those with non-conceptually based differences, should be prioritised in the DSM-V and ICD-11 development process. Prior experience with the DSM-IV and ICD-10 harmonisation effort suggests that for the process to be successful steps should be taken as early as possible.

Experimental study of visual accommodation

NASA Technical Reports Server (NTRS)

Cornsweet, T. N.; Crane, H. D.

1972-01-01

A summary report of a research effort related to the human visual accommodation system is presented. A theoretical study of the accommodation system was made. Subsequent effort was aimed at the development of specialized instrumentation for experiments designed to lead to understanding the nature of the control system in human accommodation. The necessary instrumentation consisted primarily of: (1) an automatic optometer to measure the state of eye focus, (2) a focus stimulator device to control the apparent optical distance to any target, and (3) a two-dimensional eye tracker. The concepts and designs of the first two instruments have been published in the open literature, but this report contains the first detailed treatment of the Purkinje eye tracker developed under this program. The report also discusses an accommodation lag model to explain the ability of the eye to apparently know the polarity of focus error even though the blur on the retina is to a first-approximation an even function. The interaction of the accommodation and eye movement systems is also discussed, as is the ability to train the visual accommodation system to a surprisingly responsive condition in only a few hours of training.

AIM satellite-based research bridges the unique scientific aspects of the mission to informal education programs globally

NASA Astrophysics Data System (ADS)

Robinson, D.; Maggi, B.

2003-04-01

The Education and Public Outreach (EPO) component of the satellite-based research mission "Aeronomy of Ice In the Mesosphere" (AIM) will bridge the unique scientific aspects of the mission to informal education organizations. The informal education materials developed by the EPO will utilize AIM data and educate the public about the environmental implications associated with the data. This will assist with creating a scientifically literate workforce and in developing a citizenry capable of making educated decisions related to environmental policies and laws. The objective of the AIM mission is to understand the mechanisms that cause Polar Mesospheric Clouds (PMCs) to form, how their presence affects the atmosphere, and how change in the atmosphere affects them. PMCs are sometimes known as Noctilucent Clouds (NLCs) because of their visibility during the night from appropriate locations. The phenomenon of PMCs is an observable indicator of global change, a concern to all citizens. Recent sightings of these clouds over populated regions have compelled AIM educators to expand informal education opportunities to communities worldwide. Collaborations with informal organizations include: Museums/Science Centers; NASA Sun-Earth Connection Forum; Alaska Native Ways of Knowing Project; Amateur Noctilucent Cloud Observers Organization; National Parks Education Programs; After School Science Clubs; Public Broadcasting Associations; and National Public Radio. The Native Ways of Knowing Project is an excellent example of informal collaboration with the AIM EPO. This Alaska based project will assist native peoples of the state with photographing NLCs for the EPO website. It will also aid the EPO with developing materials for informal organizations that incorporate traditional native knowledge and science, related to the sky. Another AIM collaboration that will offer citizens lasting informal education opportunities is the one established with the United States National Parks. AIM educators will work directly with the National Parks to develop education packets and web-based materials for their Junior Ranger and Parks as Classrooms programs. AIM education materials will be developed and distributed to park rangers north of 400 in an effort to include NLC observations in their night hikes. This will have a long-term impact reaching out to parents and children in an informal setting for years to come. Each of the AIM informal education collaborations will allow citizens globally an opportunity to share the excitement of the AIM mission.

School climate and delinquency among Chinese adolescents: analyses of effortful control as a moderator and deviant peer affiliation as a mediator.

PubMed

Bao, Zhenzhou; Li, Dongping; Zhang, Wei; Wang, Yanhui

2015-01-01

School climate is the quality and character of school life and reflects the norms, goals, values, interpersonal relationships, teaching and learning practices, and the organizational structure of a school. There is substantial literature documenting the negative association between positive school climate and adolescent delinquency, but little is known about the moderating and mediating mechanisms underlying this relationship. The aim of this study was to examine whether the direct and indirect pathways between school climate and adolescent delinquency would be moderated by effortful control. A sample of 2,758 Chinese adolescents (M age = 13.53 years, SD = 1.06) from 10 middle schools completed anonymous questionnaires regarding school climate, effortful control, deviant peer affiliation, and delinquency. After gender, age, geographical area, and socioeconomic status were included as covariates, the results revealed that school climate was significantly associated with adolescent delinquent behavior. This direct association was moderated by effortful control, such that the negative relationship between positive school climate and delinquency was only significant among adolescents low in effortful control. Moreover, the indirect association between school climate and delinquency via deviant peer affiliation was also moderated by effortful control. Specifically, the moderating effect of effortful control was not only manifested in the relationship between school climate and deviant peer affiliation, but also in the relationship between deviant peer affiliation and delinquency. These findings contribute to understanding the mechanisms through which positive school climate might reduce delinquent behavior and have important implications for prevention efforts aimed at diminishing adolescent delinquency.

Bridging the sanitation gap between disaster relief and development.

PubMed

Lai, Ka-Man; Ramirez, Claudia; Liu, Weilong; Kirilova, Darina; Vick, David; Mari, Joe; Smith, Rachel; Lam, Ho-Yin; Ostovari, Afshin; Shibakawa, Akifumi; Liu, Yang; Samant, Sidharth; Osaro, Lucky

2015-10-01

By interpreting disasters as opportunities to initiate the fulfilment of development needs, realise the vulnerability of the affected community and environment, and extend the legacy of relief funds and effort, this paper builds upon the concept linking relief, rehabilitation and development (LRRD) in the sanitation sector. It aims to use a composite of case studies to devise a framework for a semi-hypothetical scenario to identify critical components and generic processes for a LRRD action plan. The scenario is based on a latrine wetland sanitation system in a Muslim community. Several sub-frameworks are developed: (i) latrine design; (ii) assessment of human waste treatment; (iii) connective sanitation promotion strategy; and (iv) ecological systems and environmental services for sanitation and development. This scenario illustrates the complex issues involved in LRRD in sanitation work and provides technical notes and references for a legacy plan for disaster relief and development. © 2015 The Author(s). Disasters © Overseas Development Institute, 2015.

Developing a science of clinical utility in diagnostic classification systems field study strategies for ICD-11 mental and behavioral disorders.

PubMed

Keeley, Jared W; Reed, Geoffrey M; Roberts, Michael C; Evans, Spencer C; Medina-Mora, María Elena; Robles, Rebeca; Rebello, Tahilia; Sharan, Pratap; Gureje, Oye; First, Michael B; Andrews, Howard F; Ayuso-Mateos, José Luís; Gaebel, Wolfgang; Zielasek, Juergen; Saxena, Shekhar

2016-01-01

The World Health Organization (WHO) Department of Mental Health and Substance Abuse has developed a systematic program of field studies to evaluate and improve the clinical utility of the proposed diagnostic guidelines for mental and behavioral disorders in the Eleventh Revision of the International Classification of Diseases and Related Health Problems (ICD-11). The clinical utility of a diagnostic classification is critical to its function as the interface between health encounters and health information, and to making the ICD-11 be a more effective tool for helping the WHO's 194 member countries, including the United States, reduce the global disease burden of mental disorders. This article describes the WHO's efforts to develop a science of clinical utility in regard to one of the two major classification systems for mental disorders. We present the rationale and methodologies for an integrated and complementary set of field study strategies, including large international surveys, formative field studies of the structure of clinicians' conceptualization of mental disorders, case-controlled field studies using experimental methodologies to evaluate the impact of proposed changes to the diagnostic guidelines on clinicians' diagnostic decision making, and ecological implementation field studies of clinical utility in the global settings in which the guidelines will ultimately be implemented. The results of these studies have already been used in making decisions about the structure and content of ICD-11. If clinical utility is indeed among the highest aims of diagnostic systems for mental disorders, as their developers routinely claim, future revision efforts should continue to build on these efforts. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

Using strategic planning and organizational development principles for health promotion in an Alaska native community.

PubMed

Lardon, Cecile; Soule, Susan; Kernak, Douglas; Lupie, Henry

2011-01-01

Health promotion aims to support people in their efforts to increase control over factors that impact health and well-being. This emphasis on empowerment and contextual influences allows for a more holistic conceptualization of health and approaches to promoting health that are anchored in principles of community development and systems change. Piciryaratgun Calritllerkaq (Healthy Living Through A Healthy Lifestyle) is a collaboration between a Yup'ik village in rural Alaska and researchers from the University of Alaska Fairbanks. The goal was to improve nutrition, increase exercise, and decrease stress. The project utilized elements of organization development and strategic planning to develop a local infrastructure and process and to promote local expertise. The project team developed goals, objectives, action, and evaluation plans that integrated local traditions, Yup'ik culture, and research.

Mining and Development of Novel SSR Markers Using Next Generation Sequencing (NGS) Data in Plants.

PubMed

Taheri, Sima; Lee Abdullah, Thohirah; Yusop, Mohd Rafii; Hanafi, Mohamed Musa; Sahebi, Mahbod; Azizi, Parisa; Shamshiri, Redmond Ramin

2018-02-13

Microsatellites, or simple sequence repeats (SSRs), are one of the most informative and multi-purpose genetic markers exploited in plant functional genomics. However, the discovery of SSRs and development using traditional methods are laborious, time-consuming, and costly. Recently, the availability of high-throughput sequencing technologies has enabled researchers to identify a substantial number of microsatellites at less cost and effort than traditional approaches. Illumina is a noteworthy transcriptome sequencing technology that is currently used in SSR marker development. Although 454 pyrosequencing datasets can be used for SSR development, this type of sequencing is no longer supported. This review aims to present an overview of the next generation sequencing, with a focus on the efficient use of de novo transcriptome sequencing (RNA-Seq) and related tools for mining and development of microsatellites in plants.

Using strategic planning and organizational development principles for health promotion in an Alaska Native community

PubMed Central

Lardon, Cécile; Soule, Susan; Kernak, Douglas; Lupie, Henry

2011-01-01

SUMMARY Health promotion aims to support people in their efforts to increase control over factors that impact health and well-being. This emphasis on empowerment and contextual influences allows for a more holistic conceptualization of health and approaches to promoting health that are anchored in principles of community development and systems change. Piciryaratgun Calritllerkaq (Healthy Living Through A Healthy Lifestyle) is a collaboration between a Yup’ik village in rural Alaska and researchers from the University of Alaska Fairbanks. The goal was to improve nutrition, increase exercise and decrease stress. The project utilized elements of organization development and strategic planning to develop a local infrastructure and process and to promote local expertise. The project team developed goals, objectives, action and evaluation plans that integrated local traditions, Yup’ik culture, and research. PMID:21271433

Identifying Cognitive Mechanisms Targeted for Treatment Development in Schizophrenia: An Overview of the First Meeting of the Cognitive Neuroscience Treatment Research to Improve Cognition in Schizophrenia (CNTRICS) Initiative

PubMed Central

Carter, Cameron S.; Barch, Deanna M.; Buchanan, Robert W.; Bullmore, Ed; Krystal, John H.; Cohen, Jonathan; Geyer, Mark; Green, Michael; Nuechterlein, Keith H.; Robbins, Trevor; Silverstein, Steven; Smith, Edward E.; Strauss, Milton; Wykes, Til; Heinssen, Robert

2008-01-01

This overview describes the generation and development of the ideas that led to the Cognitive Neuroscience Treatment Research to Improve Cognition in Schizophrenia (CNTRICS) initiative. It also describes the organization, process and products of the first meeting. The CNTRICS initiative involves a series of three conferences that will systematically address barriers to translating paradigms developed in the basic animal and human cognitive neuroscience fields for use in translational research aimed at developing novel treatments for cognitive impairments in schizophrenia. The articles in this special section report on the results of the first conference, which used a criterion based consensus-building process to develop a set of cognitive constructs to be targeted for translation efforts. PMID:18466880

Sustainability of State-Level Substance Abuse Prevention Infrastructure After the Completion of the SPF SIG.

PubMed

Edwards, Jessica M; Stein-Seroussi, Al; Flewelling, Robert L; Orwin, Robert G; Zhang, Lei

2015-06-01

Recent national substance abuse prevention efforts that have been disseminated at the state level have provided fertile ground for addressing the dearth of systematic research on state-level substance abuse prevention infrastructure. The Strategic Prevention Framework State Incentive Grant Program (SPF SIG), a national public health initiative sponsored by the US Substance Abuse and Mental Health Services Administration and its Center for Substance Abuse Prevention, is one such effort, providing an opportunity to examine state-level substance abuse prevention infrastructure across the country. The aims of the SPF SIG initiative include reducing substance abuse and its related problems, as well as enhancing state and local prevention infrastructure and capacity. In this article, we describe the status of state-level substance abuse prevention infrastructure and capacity 1 year after the first 26 funded states ended their projects, based on follow-up interviews with state prevention decision-makers. We found that, in five of the six prevention domains we measured, prevention infrastructure capacity increased during the 12-month period after the grants ended. The evidence for further SPF capacity development even after the conclusion of the grants suggests that states recognized the benefits of using the SPF and took deliberate steps to sustain and enhance the integration of this framework into their state prevention systems. In addition, the findings suggest that state agencies and organizations can benefit from time-limited resources aimed at increasing their capacity and that such efforts can have a lasting impact on measures of state prevention system capacity.

Lessons Learned for Collaborative Clinical Content Development

PubMed Central

Collins, S.A.; Bavuso, K.; Zuccotti, G.; Rocha, R.A.

2013-01-01

Background Site-specific content configuration of vendor-based Electronic Health Records (EHRs) is a vital step in the development of standardized and interoperable content that can be used for clinical decision-support, reporting, care coordination, and information exchange. The multi-site, multi-stakeholder Acute Care Documentation (ACD) project at Partners Healthcare Systems (PHS) aimed to develop highly structured clinical content with adequate breadth and depth to meet the needs of all types of acute care clinicians at two academic medical centers. The Knowledge Management (KM) team at PHS led the informatics and knowledge management effort for the project. Objectives We aimed to evaluate the role, governance, and project management processes and resources for the KM team’s effort as part of the standardized clinical content creation. Methods We employed the Center for Disease Control’s six step Program Evaluation Framework to guide our evaluation steps. We administered a forty-four question, open-ended, semi-structured voluntary survey to gather focused, credible evidence from members of the KM team. Qualitative open-coding was performed to identify themes for lessons learned and concluding recommendations. Results Six surveys were completed. Qualitative data analysis informed five lessons learned and thirty specific recommendations associated with the lessons learned. The five lessons learned are: 1) Assess and meet knowledge needs and set expectations at the start of the project; 2) Define an accountable decision-making process; 3) Increase team meeting moderation skills; 4) Ensure adequate resources and competency training with online asynchronous collaboration tools; 5) Develop focused, goal-oriented teams and supportive, consultative service based teams. Conclusions Knowledge management requirements for the development of standardized clinical content within a vendor-based EHR among multi-stakeholder teams and sites include: 1) assessing and meeting informatics knowledge needs, 2) setting expectations and standardizing the process for decision-making, and 3) ensuring the availability of adequate resources and competency training. PMID:23874366

Development of quality measures for monitoring and improving care in gastroenterology.

PubMed

Germansky, Katharine A; Leffler, Daniel A

2011-06-01

Over the past decade, most quality assurance (QA) efforts in gastroenterology have been aimed at endoscopy. Endoscopic quality improvement was the rational area to begin QA work in gastroenterology due to the relatively acute nature of complications and the high volume of procedures performed. While endoscopy is currently the focus of most quality assurance (QA) measures in gastroenterology, more recent efforts have begun to address clinical gastroenterology practices both in the outpatient and inpatient settings. Clinical outpatient and inpatient gastroenterology is laden with areas where standardization could benefit patient care. While data and experience in clinical gastroenterology QA is relatively limited, it is clear that inconsistent use of guidelines and practice variations in gastroenterology can lead to lower quality care. In this review, we review a variety of areas in clinical gastroenterology where existing guidelines and published data suggest both the need and practicality of active QA measures. Copyright © 2011 Elsevier Ltd. All rights reserved.

Fretting Fatigue of Single Crystal/Polycrystalline Nickel Subjected to Blade/Disk Contact Loading

NASA Astrophysics Data System (ADS)

Matlik, J. F.; Murthy, H.; Farris, T. N.

2002-01-01

Fretting fatigue describes the formation and growth of cracks at the edge-of-contact of nominally clamped components subjected to cyclic loading. Components that are known to be subject to fretting fatigue include riveted lap joints and blade/disk contacts in launch vehicle turbomachinery. Recent efforts have shown that conventional mechanics tools, both fatigue and fracture based, can be used to model fretting fatigue experiments leading to successful life predictions. In particular, experiments involving contact load configurations similar to those that occur in the blade/disk connection of gas turbine engines have been performed extensively. Predictions of fretting fatigue life have been compared favorably to experimental observations [1]. Recent efforts are aimed at performing experiments at higher temperatures as shown in the photograph below along with a sample fracture surface. The talk will describe the status of these experiments as will as model developments relevant to the single crystal material properties.

Sustainability and optimal control of an exploited prey predator system through provision of alternative food to predator.

PubMed

Kar, T K; Ghosh, Bapan

2012-08-01

In the present paper, we develop a simple two species prey-predator model in which the predator is partially coupled with alternative prey. The aim is to study the consequences of providing additional food to the predator as well as the effects of harvesting efforts applied to both the species. It is observed that the provision of alternative food to predator is not always beneficial to the system. A complete picture of the long run dynamics of the system is discussed based on the effort pair as control parameters. Optimal augmentations of prey and predator biomass at final time have been investigated by optimal control theory. Also the short and large time effects of the application of optimal control have been discussed. Finally, some numerical illustrations are given to verify our analytical results with the help of different sets of parameters. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

A glossary of theories for understanding policymaking.

PubMed

Smith, Katherine Elizabeth; Katikireddi, Srinivasa Vittal

2013-02-01

Public health practitioners and researchers often seek to influence public policies in order to improve population health and/or reduce health inequalities. However, these efforts frequently appear to be uninformed by the many empirically-based theories about policymaking that have been developed within political science. This glossary provides a brief overview of some of the most popular of these theories, describing how each: frames the policymaking process; portrays the relationships and influence of specific policy actors; and depicts the potential for policy change (or inertia). Examples of their application to public health are provided to help improve understanding of the material presented. Throughout the article, the implications of the different theories for public health researchers and advocates seeking to inform policy decisions are emphasised. The glossary aims to provide an accessible overview to key theories about policy and decision-making, with a view to supporting public health efforts to achieve healthier public policies.

Ethical Dilemmas in Disaster Medicine

PubMed Central

Ozge Karadag, C; Kerim Hakan, A

2012-01-01

Background Disasters may lead to ethical challenges that are different from usual medical practices. In addition, disaster situations are related with public health ethics more than medical ethics, and accordingly may require stronger effort to achieve a balance between individual and collective rights. This paper aims to review some ethical dilemmas that arise in disasters and mainly focuses on health services. Disasters vary considerably with respect to their time, place and extent; therefore, ethical questions may not always have `one-size-fits-all` answers. On the other hand, embedding ethical values and principles in every aspect of health-care is of vital importance. Reviewing legal and organizational regulations, developing health-care related guidelines, and disaster recovery plans, establishing on-call ethics committees as well as adequate in-service training of health-care workers for ethical competence are among the most critical steps. It is only by making efforts before disasters, that ethical challenges can be minimized in disaster responses. PMID:23285411

Cardiovascular health in the Americas: facts, priorities and the UN high-level meeting on non-communicable diseases.

PubMed

Ordúñez, Pedro

2011-10-01

Population aging, smoking, unhealthy diet and physical inactivity, in the context of globalization and unregulated urbanization, explain the high prevalences of hypertension, hypercholesterolemia and diabetes in the Americas, making cardiovascular diseases the main cause of death. Moreover, cardiovascular diseases and their risk factors disproportionately affect the poorest people, obstructing antipoverty efforts and further deepening health and other inequities. The global crisis of chronic non-communicable diseases has reached such proportions that the UN General Assembly called a high-level meeting in September 2011 to address the issue as one of human development, aiming to stimulate political commitment to a concerted global effort to stem the pandemic. In reference to the Americas, this article reviews the burden of cardiovascular diseases and describes priorities for strategies and action in the region and their relation to the results of the UN meeting.

Regeneration of the anterior cruciate ligament: Current strategies in tissue engineering

PubMed Central

Nau, Thomas; Teuschl, Andreas

2015-01-01

Recent advancements in the field of musculoskeletal tissue engineering have raised an increasing interest in the regeneration of the anterior cruciate ligament (ACL). It is the aim of this article to review the current research efforts and highlight promising tissue engineering strategies. The four main components of tissue engineering also apply in several ACL regeneration research efforts. Scaffolds from biological materials, biodegradable polymers and composite materials are used. The main cell sources are mesenchymal stem cells and ACL fibroblasts. In addition, growth factors and mechanical stimuli are applied. So far, the regenerated ACL constructs have been tested in a few animal studies and the results are encouraging. The different strategies, from in vitro ACL regeneration in bioreactor systems to bio-enhanced repair and regeneration, are under constant development. We expect considerable progress in the near future that will result in a realistic option for ACL surgery soon. PMID:25621217

An Assessment of New Satellite Data Products for the Development of a Long-Term Global Solar Resource at 10-100 km

DOE Office of Scientific and Technical Information (OSTI.GOV)

Stackhouse Jr., Paul W.; Minnis, Patrick; Perez, Richard

A project representing an effort to reprocess the NASA based solar resource data sets is reviewed. The effort represented a collaboration between NASA, NOAA, NREL and the SUNY-Albany and aimed to deliver a 10 km resolution, 3-hourly data set spanning from 1983 through near-present. Part of the project was to transition project capability to NREL for annual processing to extend data set. Due to delays in the key input project called ISCCP, we evaluate only Beta versions of this data set and also introduce the potential use of another NASA Langley based cloud data set for the CERES project. Themore » CERES project uses these cloud properties to compute global top-of-atmosphere and surface fluxes at the 1x1 degree resolution. Here, we also briefly discuss these data sets in potential usage for solar resource benchmarking.« less

Agreement for NASA/OAST - USAF/AFSC space interdependency on spacecraft environment interaction

NASA Technical Reports Server (NTRS)

Pike, C. P.; Stevens, N. J.

1980-01-01

A joint AF/NASA comprehensive program on spacecraft environment interactions consists of combined contractual and in house efforts aimed at understanding spacecraft environment ineraction phenomena and relating ground test results to space conditions. Activities include: (1) a concerted effort to identify project related environmental interactions; (2) a materials investigation to measure the basic properties of materials and develop or modify materials as needed; and (3) a ground simulation investigation to evaluate basic plasma interaction phenomena and provide inputs to the analytical modeling investigation. Systems performance is evaluated by both ground tests and analysis. There is an environmental impact investigation to determine the effect of future large spacecraft on the charged particle environment. Space flight investigations are planned to verify the results. The products of this program are test standards and design guidelines which summarize the technology, specify test criteria, and provide techniques to minimize or eliminate system interactions with the charged particle environment.

Coproduction of healthcare service

PubMed Central

Batalden, Maren; Batalden, Paul; Margolis, Peter; Seid, Michael; Armstrong, Gail; Opipari-Arrigan, Lisa; Hartung, Hans

2016-01-01

Efforts to ensure effective participation of patients in healthcare are called by many names—patient centredness, patient engagement, patient experience. Improvement initiatives in this domain often resemble the efforts of manufacturers to engage consumers in designing and marketing products. Services, however, are fundamentally different than products; unlike goods, services are always ‘coproduced’. Failure to recognise this unique character of a service and its implications may limit our success in partnering with patients to improve health care. We trace a partial history of the coproduction concept, present a model of healthcare service coproduction and explore its application as a design principle in three healthcare service delivery innovations. We use the principle to examine the roles, relationships and aims of this interdependent work. We explore the principle's implications and challenges for health professional development, for service delivery system design and for understanding and measuring benefit in healthcare services. PMID:26376674

Teaching Introductory Astronomy "Open and Out" & Looking Forward to the 2017 Solar Eclipse

NASA Astrophysics Data System (ADS)

Chu, I.-Wen Mike; Cronkhite, Jeff

2016-01-01

We present a new effort on teaching introductory astronomy addressing the specific challenges facing small colleges including limited resources, changing generational behavior and new technological trends. The approach adopts open source solutions into the developmental learning materials aiming for standardization and wide-scale applicability. In addition we utilize events and resources outside classroom into the learning. Among examples of the development are laboratory exercises based on the planetarium software Stellarium and remediation exercises using Khan Academy instructional videos. As the eventual goal is to move toward greater autonomy the cycles of improvement necessarily require student feedback in an entirely different instructional style based on egalitarian dialogues. We highlight a laboratory exercise on Earth-Moon distance estimation using parallax of the upcoming 2017 solar eclipse to illustrate the "open and out" philosophy. Achievements, limitations and some diagnostics of the current effort are also presented.

An Assessment of New Satellite Data Products for the Development of a Long-Term Global Solar Resource at 10-100 km

NASA Technical Reports Server (NTRS)

Stackhouse, Paul W., Jr.; Minnis, Patrick; Perez, Richard; Sengupta, Manajit; Knapp, Kenneth; Mikovitz, J. Colleen; Schlemmer, James; Scarino, Benjamin; Zhang, Taiping; Cox, Stephen J.

2016-01-01

A project representing an effort to reprocess the NASA based solar resource data sets is reviewed. The effort represented a collaboration between NASA, NOAA, NREL and the SUNY-Albany and aimed to deliver a 10 km resolution, 3-hourly data set spanning from 1983 through near-present. Part of the project was to transition project capability to NREL for annual processing to extend data set. Due to delays in the key input project called ISCCP, we evaluate only Beta versions of this data set and also introduce the potential use of another NASA Langley based cloud data set for the CERES project. The CERES project uses these cloud properties to compute global top-of-atmosphere and surface fluxes at the 1x1 degree resolution. Here, we also briefly discuss these data sets in potential usage for solar resource benchmarking.

The RCSB Protein Data Bank: views of structural biology for basic and applied research and education

PubMed Central

Rose, Peter W.; Prlić, Andreas; Bi, Chunxiao; Bluhm, Wolfgang F.; Christie, Cole H.; Dutta, Shuchismita; Green, Rachel Kramer; Goodsell, David S.; Westbrook, John D.; Woo, Jesse; Young, Jasmine; Zardecki, Christine; Berman, Helen M.; Bourne, Philip E.; Burley, Stephen K.

2015-01-01

The RCSB Protein Data Bank (RCSB PDB, http://www.rcsb.org) provides access to 3D structures of biological macromolecules and is one of the leading resources in biology and biomedicine worldwide. Our efforts over the past 2 years focused on enabling a deeper understanding of structural biology and providing new structural views of biology that support both basic and applied research and education. Herein, we describe recently introduced data annotations including integration with external biological resources, such as gene and drug databases, new visualization tools and improved support for the mobile web. We also describe access to data files, web services and open access software components to enable software developers to more effectively mine the PDB archive and related annotations. Our efforts are aimed at expanding the role of 3D structure in understanding biology and medicine. PMID:25428375

Teaching With and About Nature of Science, and Science Teacher Knowledge Domains

NASA Astrophysics Data System (ADS)

Abd-El-Khalick, Fouad

2013-09-01

The ubiquitous goals of helping precollege students develop informed conceptions of nature of science (NOS) and experience inquiry learning environments that progressively approximate authentic scientific practice have been long-standing and central aims of science education reforms around the globe. However, the realization of these goals continues to elude the science education community partly because of a persistent, albeit not empirically supported, coupling of the two goals in the form of `teaching about NOS with inquiry'. In this context, the present paper aims, first, to introduce the notions of, and articulate the distinction between, teaching with and about NOS, which will allow for the meaningful coupling of the two desired goals. Second, the paper aims to explicate science teachers' knowledge domains requisite for effective teaching with and about NOS. The paper argues that research and development efforts dedicated to helping science teachers develop deep, robust, and integrated NOS understandings would have the dual benefits of not only enabling teachers to convey to students images of science and scientific practice that are commensurate with historical, philosophical, sociological, and psychological scholarship (teaching about NOS), but also to structure robust inquiry learning environments that approximate authentic scientific practice, and implement effective pedagogical approaches that share a lot of the characteristics of best science teaching practices (teaching with NOS).

The Recovery Spectrum

PubMed Central

Tucker, Jalie A.; Simpson, Cathy A.

2011-01-01

Recent innovations in alcohol-focused interventions are aimed at closing the gap between population need and the currently uncommon use of alcohol treatment services. Guided by population data showing the heterogeneity of alcohol problems and the occurrence of natural remissions from problem drinking without treatment, alcohol services have begun to expand beyond clinical treatment to offer the untreated majority of individuals with alcohol-related problems accessible, less-intensive services that use the tools of public health practice. These services often are opportunistic, meaning they can be provided in primary-care or other unspecialized health care or community settings. They also can be delivered by nonspecialists, or can be used by people themselves to address problems with alcohol without entering the health care system. This developing spectrum of services includes screening and brief interventions, guided self-change programs, and telehealth options that often are targeted and tailored for high-risk groups (e.g., college drinkers). Other efforts aimed at reducing barriers to care and increasing motivation to seek help have utilized individual, organizational, and public health strategies. Together, these efforts have potential for helping the treatment field reach people who have realized that they have a drinking problem but have not yet experienced the severe negative consequences that may eventually drive them to seek treatment. Although the evidence supporting several innovations in alcohol services is preliminary, some approaches are well established, and collectively they form an emerging continuum of care for alcohol problems aimed at increasing service availability and improving overall impact on population health. PMID:23580021

Predicting Consumer Effort in Finding and Paying for Health Care: Expert Interviews and Claims Data Analysis.

PubMed

Long, Sandra; Monsen, Karen A; Pieczkiewicz, David; Wolfson, Julian; Khairat, Saif

2017-10-12

For consumers to accept and use a health care information system, it must be easy to use, and the consumer must perceive it as being free from effort. Finding health care providers and paying for care are tasks that must be done to access treatment. These tasks require effort on the part of the consumer and can be frustrating when the goal of the consumer is primarily to receive treatments for better health. The aim of this study was to determine the factors that result in consumer effort when finding accessible health care. Having an understanding of these factors will help define requirements when designing health information systems. A panel of 12 subject matter experts was consulted and the data from 60 million medical claims were used to determine the factors contributing to effort. Approximately 60 million claims were processed by the health care insurance organization in a 12-month duration with the population defined. Over 292 million diagnoses from claims were used to validate the panel input. The results of the study showed that the number of people in the consumer's household, number of visits to providers outside the consumer's insurance network, number of adjusted and denied medical claims, and number of consumer inquiries are a proxy for the level of effort in finding and paying for care. The effort level, so measured and weighted per expert panel recommendations, differed by diagnosis. This study provides an understanding of how consumers must put forth effort when engaging with a health care system to access care. For higher satisfaction and acceptance results, health care payers ideally will design and develop systems that facilitate an understanding of how to avoid denied claims, educate on the payment of claims to avoid adjustments, and quickly find providers of affordable care. ©Sandra Long, Karen A. Monsen, David Pieczkiewicz, Julian Wolfson, Saif Khairat. Originally published in JMIR Medical Informatics (http://medinform.jmir.org), 12.10.2017.

Concepts and challenges in quantitative pharmacology and model-based drug development.

PubMed

Zhang, Liping; Pfister, Marc; Meibohm, Bernd

2008-12-01

Model-based drug development (MBDD) has been recognized as a concept to improve the efficiency of drug development. The acceptance of MBDD from regulatory agencies, industry, and academia has been growing, yet today's drug development practice is still distinctly distant from MBDD. This manuscript is aimed at clarifying the concept of MBDD and proposing practical approaches for implementing MBDD in the pharmaceutical industry. The following concepts are defined and distinguished: PK-PD modeling, exposure-response modeling, pharmacometrics, quantitative pharmacology, and MBDD. MBDD is viewed as a paradigm and a mindset in which models constitute the instruments and aims of drug development efforts. MBDD covers the whole spectrum of the drug development process instead of being limited to a certain type of modeling technique or application area. The implementation of MBDD requires pharmaceutical companies to foster innovation and make changes at three levels: (1) to establish mindsets that are willing to get acquainted with MBDD, (2) to align processes that are adaptive to the requirements of MBDD, and (3) to create a closely collaborating organization in which all members play a role in MBDD. Pharmaceutical companies that are able to embrace the changes MBDD poses will likely be able to improve their success rate in drug development, and the beneficiaries will ultimately be the patients in need.

Standards Draw Heat in States

ERIC Educational Resources Information Center

Ujifusa, Andrew

2013-01-01

Opponents of the Common Core State Standards are ramping up legislative pressure and public relations efforts aimed at getting states to scale back--or even abandon--the high-profile initiative, even as implementation proceeds and tests aligned with the standards loom. Critics of the common core have focused recent lobbying and media efforts on…

Managerialism and the Risky Business of Quality Assurance in Universities

ERIC Educational Resources Information Center

Davis, Annemarie

2017-01-01

Purpose: This paper aims to identify what is needed to enhance academic quality assurance in a university, with specific efforts to reduce the risks associated with ritualised quality assurance practices. Design/methodology/approach: The aspects to enhance academic quality assurance efforts in managerial universities are identified through a…

77 FR 38277 - Wind and Water Power Program

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-27

..., modeling, and database efforts. This meeting will be a technical discussion to provide those involved in... ecological survey, modeling, and database efforts in the waters off the Mid-Atlantic. The workshop aims to... models and compatible Federal and regional databases. It is not the object of this session to obtain any...

School Reform Efforts for Lesbian, Gay, Bisexual, and Transgendered Students

ERIC Educational Resources Information Center

Mayberry, Maralee

2006-01-01

Recent efforts of school personnel across the country to implement a variety of initiatives aimed at providing safe and tolerant learning environments for lesbian, gay, bisexual, and transgendered (LGBT) students have resulted in inclusion of homosexual identities in school curricula, identification of positive role models, counseling programs,…

2013 Snapshot of NGSI Human Capital Development and Future Roadmap

DOE Office of Scientific and Technical Information (OSTI.GOV)

Scholz, Melissa A; Poe, Sarah M; Dewji, Shaheen A

2013-01-01

Since its creation in 2008, the Human Capital Development (HCD) subprogram of NNSA s Next Generation Safeguards Initiative (NGSI) has been striving to develop sustainable academic and technical programs that support the recruitment, education, training, and retention of the next generation of international safeguards professionals. This effort endeavors to develop additional human resources to equip a new cadre of safeguards and nonproliferation experts to meet the needs of both the United States and the International Atomic Energy Agency (IAEA) for decades to come, specifically in response to data that indicates that 82% of the 2009 safeguards experts at U.S. Laboratoriesmore » will have left the workforce within 15 years. This paper provides an update on the status of the program since its last presentation at the INMM Annual Meeting in 2010, including strengthened and integrated efforts in the areas of graduate and post-doctoral fellowships, young and mid-career professional support, additional short safeguards coursework, and expanded university engagement. In particular, the paper will cover the NGSI Human Capital Roadmap currently being developed in safeguards and nonproliferation education, training, and knowledge retention. The NGSI Human Capital Roadmap aims to provide additional data points and metrics on where the human capital demand lies, which disciplines and skill sets are needed in the field, and how NGSI HCD can best address these issues to meet future demand.« less

Speech adjustments for room acoustics and their effects on vocal effort

PubMed Central

Bottalico, Pasquale

2016-01-01

Objectives The aims of the present study are: (1) to analyze the effects of the acoustical environment and the voice style on time dose (Dt_p,) and fundamental frequency (mean fo and standard deviation std_fo), while taking into account the effect of short term vocal fatigue; (2) to predict the self-reported vocal effort from the voice acoustical parameters. Methods Ten male and ten female subjects were recorded while reading a text in normal and loud styles, in three rooms - anechoic, semi-reverberant and reverberant –with and without acrylic glass panels 0.5 m from the mouth, which increased external auditory feedback. Subjects quantified how much effort was required to speak in each condition on a visual analogue scale after each task. Results (Aim1) In the loud style, Dt_p, fo and std_fo increased. The Dt_p was higher in the reverberant room compared to the other two rooms. Both genders tended to increase fo in less reverberant environments, while a more monotonous speech was produced in rooms with greater reverberation. All three voice parameters increased with short-term vocal fatigue. (Aim2) A model of the vocal effort to acoustic vocal parameters is proposed. The SPL (Sound Pressure Level) contributed to 66% of the variance explained by the model, followed by the fundamental frequency (30%) and the modulation in amplitude (4%). Conclusions The results provide insight into how voice acoustical parameters can predict vocal effort. In particular, it increased when SPL and fo increased and when the amplitude voice modulation (std_ΔSPL) decreased. PMID:28029555

Semantic Support for Complex Ecosystem Research Environments

NASA Astrophysics Data System (ADS)

Klawonn, M.; McGuinness, D. L.; Pinheiro, P.; Santos, H. O.; Chastain, K.

2015-12-01

As ecosystems come under increasing stresses from diverse sources, there is growing interest in research efforts aimed at monitoring, modeling, and improving understanding of ecosystems and protection options. We aimed to provide a semantic infrastructure capable of representing data initially related to one large aquatic ecosystem research effort - the Jefferson project at Lake George. This effort includes significant historical observational data, extensive sensor-based monitoring data, experimental data, as well as model and simulation data covering topics including lake circulation, watershed runoff, lake biome food webs, etc. The initial measurement representation has been centered on monitoring data and related provenance. We developed a human-aware sensor network ontology (HASNetO) that leverages existing ontologies (PROV-O, OBOE, VSTO*) in support of measurement annotations. We explicitly support the human-aware aspects of human sensor deployment and collection activity to help capture key provenance that often is lacking. Our foundational ontology has since been generalized into a family of ontologies and used to create our human-aware data collection infrastructure that now supports the integration of measurement data along with simulation data. Interestingly, we have also utilized the same infrastructure to work with partners who have some more specific needs for specifying the environmental conditions where measurements occur, for example, knowing that an air temperature is not an external air temperature, but of the air temperature when windows are shut and curtains are open. We have also leveraged the same infrastructure to work with partners more interested in modeling smart cities with data feeds more related to people, mobility, environment, and living. We will introduce our human-aware data collection infrastructure, and demonstrate how it uses HASNetO and its supporting SOLR-based search platform to support data integration and semantic browsing. Further we will present learnings from its use in three relatively diverse large ecosystem research efforts and highlight some benefits and challenges related to our semantically-enhanced foundation.

Does increased effort compensate for performance debilitating test anxiety?

PubMed

Putwain, David W; Symes, Wendy

2018-05-24

It is well established that test anxiety is negatively related to examination performance. Based on attentional control theory, the aim of this study was to examine whether increased effort can protect against performance debilitating test anxiety. Four hundred and sixty-six participants (male = 228; 48.9%; White = 346, 74.3%; mean age = 15.7 years) completed self-report measures of test anxiety and effort that were matched to performance on a high-stakes secondary school examination. The worry and bodily symptoms components of test anxiety were negatively, and effort, positively related to examination performance. Effort moderated the negative relation between bodily symptoms and examination performance. At low effort, the negative relationship was amplified and at high effort was attenuated. Compensatory effort protects performance against bodily symptoms but not worry. It is possible that the cognitive load on working memory arising from the combination of worry and examination demands may be too high to be compensated by effort. (PsycINFO Database Record (c) 2018 APA, all rights reserved).

Community Evaluation for Economic Development. Small Town Strategy.

ERIC Educational Resources Information Center

Gault, George H.; Coppedge, Robert O.

Many communities have economic development efforts, which are generally undertaken in an attempt to create productive employment opportunities and to strengthen the local tax base. Unfortunatley, the economic development efforts of many communities, especially rural communities, are not productive ones. Many rural development efforts fail because…

A Brief History of Airborne Self-Spacing Concepts

NASA Technical Reports Server (NTRS)

Abbott, Terence S.

2009-01-01

This paper presents a history of seven of the more significant airborne and airborne-assisted aircraft spacing concepts that have been developed and evaluated during the past 40 years. The primary focus of the earlier concepts was on enhancing airport terminal area productivity and reducing air traffic controller workload. The more recent efforts were designed to increase runway throughput through improved aircraft spacing precision at landing. The latest concepts are aimed at supporting more fuel efficient and lower community noise operations while maintaining or increasing runway throughput efficiency.

Progress report No. 2, design of new pile area {open_quotes}G,{close_quotes} Project C-300, Atomic Energy Commission Directive HW-104

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lowe, P.E.

1950-01-16

This document is the progress report for the design and development of Pile Area {open_quotes}G{close_quotes}, to cover the period June 1, 1949 to December 31, 1949. This project represents the major effort of the Reactor Division of the Design and Construction Divisions. It is being pursued with the aim of being able to incorporate the major project objectives in a finished pile design if that design is begun about January, 1951.

Design approaches to more energy efficient engines

NASA Technical Reports Server (NTRS)

Saunders, N. T.; Colladay, R. S.; Macioce, L. E.

1978-01-01

The status of NASA's Energy Efficient Engine Project, a comparative government-industry effort aimed at advancing the technology base for the next generation of large turbofan engines for civil aircraft transports is summarized. Results of recently completed studies are reviewed. These studies involved selection of engine cycles and configurations that offer potential for at least 12% lower fuel consumption than current engines and also are economically attractive and environmentally acceptable. Emphasis is on the advancements required in component technologies and systems design concepts to permit future development of these more energy efficient engines.

Special Issue: Materials for Electrochemical Capacitors and Batteries.

PubMed

Wang, Jian-Gan; Wei, Bingqing

2017-04-22

Electrochemical capacitors and rechargeable batteries have received worldwide attention due to their excellent energy storage capability for a variety of applications. The rapid development of these technologies is propelled by the advanced electrode materials and new energy storage systems. It is believed that research efforts can improve the device performance to meet the ever-increasing requirements of high energy density, high power density and long cycle life. This Special Issue aims to provide readers with a glimpse of different kinds of electrode materials for electrochemical capacitors and batteries.

A Better Way to Excise Inhibitory Molecules (CSPGs) from a Spinal Cord Injury Scar to Promote Regeneration

DTIC Science & Technology

2011-10-01

19145984) Zhang, G. ,R.-L. Lin, M. Wiggers, D.M. Snow, and L.-Y. Lee. (2008) Altered expression of TRPV1 and sensitivity to capsaicin in pulmonary...neurons. "Role of TRPV1 in Airway Hypersensitivity Induced by Inflammation" - ACTIVE PI: Lu-Yuan Lee; Co-I: D. Snow, 5% effort; 9/1/09 - 8/31/11...Agency: NIH - National Heart, Lung and Blood Institute; 1R01 (HL096914-01) Aims: To investigate the role of TRPV1 in the development of airway

Stratospheric cruise emission reduction program

NASA Technical Reports Server (NTRS)

Diehl, L. A.; Reck, G. M.; Marek, C. J.; Szaniszlo, A. J.

1977-01-01

A recently implemented NASA effort specifically aimed at reducing cruise oxides of nitrogen from high-altitude aircraft is discussed. The desired emission levels and the combustor technology required to achieve them are discussed. A brief overview of the SCERP operating plan is given. Lean premixed-prevaporized combustion and some of the potential difficulties that are associated with applying this technique to gas turbine combustors are examined. Base technology was developed in several key areas. These fundamental studies are viewed as a requirement for successful implementation of the lean premixed combustion technique.

Imaging and characterization of primary and secondary radiation in ion beam therapy

NASA Astrophysics Data System (ADS)

Granja, Carlos; Martisikova, Maria; Jakubek, Jan; Opalka, Lukas; Gwosch, Klaus

2016-07-01

Imaging in ion beam therapy is an essential and increasingly significant tool for treatment planning and radiation and dose deposition verification. Efforts aim at providing precise radiation field characterization and online monitoring of radiation dose distribution. A review is given of the research and methodology of quantum-imaging, composition, spectral and directional characterization of the mixed-radiation fields in proton and light ion beam therapy developed by the IEAP CTU Prague and HIT Heidelberg group. Results include non-invasive imaging of dose deposition and primary beam online monitoring.

(abstract) Scaling Nominal Solar Cell Impedances for Array Design

NASA Technical Reports Server (NTRS)

Mueller, Robert L; Wallace, Matthew T.; Iles, Peter

1994-01-01

This paper discusses a task the objective of which is to characterize solar cell array AC impedance and develop scaling rules for impedance characterization of large arrays by testing single solar cells and small arrays. This effort is aimed at formulating a methodology for estimating the AC impedance of the Mars Pathfinder (MPF) cruise and lander solar arrays based upon testing single cells and small solar cell arrays and to create a basis for design of a single shunt limiter for MPF power control of flight solar arrays having very different inpedances.

An Integrative Review of Cybercivility in Health Professions Education.

PubMed

De Gagne, Jennie C; Choi, Min; Ledbetter, Leila; Kang, Hee Sun; Clark, Cynthia M

2016-01-01

Although incivility in higher education has been widely described, little evidence exists regarding incivility among health professions students in online environments. This study aims to integrate literature on cybercivility in health professions education. The extent to which health professions students and faculty experience cyberincivility, the direct and indirect effects and actions taken after cyberincivility, and themes that guide facilitation of cybercivility are discussed. Efforts to prevent cyberincivility can be achieved through focused education on cybercivility, development of clear policies related to its consequences, and formulation of guidelines for both student and faculty behavior online.

Informatics for neglected diseases collaborations.

PubMed

Bost, Frederic; Jacobs, Robert T; Kowalczyk, Paul

2010-05-01

Many different public and private organizations from across the globe are collaborating on neglected diseases drug-discovery and development projects with the aim of identifying a cure for tropical infectious diseases. These neglected diseases collaborations require a global, secure, multi-organization data-management solution, combined with a platform that facilitates communication and supports collaborative work. This review discusses the solutions offered by 'Software as a Service' (SaaS) web-based platforms, despite notable challenges, and the evolution of these platforms required to foster efficient virtual research efforts by geographically dispersed scientists.

Approaches to virtual screening and screening library selection.

PubMed

Wildman, Scott A

2013-01-01

The ease of access to virtual screening (VS) software in recent years has resulted in a large increase in literature reports. Over 300 publications in the last year report the use of virtual screening techniques to identify new chemical matter or present the development of new virtual screening techniques. The increased use is accompanied by a corresponding increase in misuse and misinterpretation of virtual screening results. This review aims to identify many of the common difficulties associated with virtual screening and allow researchers to better assess the reliability of their virtual screening effort.

A Variable Diameter Short Haul Civil Tiltrotor

NASA Technical Reports Server (NTRS)

Wang, James M.; Jones, Christopher T.; Nixon, Mark W.

1999-01-01

The Short-Haul-Civil-tiltrotor (SHCT) component of the NASA Aviation System Capacity Program is an effort to develop the technologies needed for a potential 40-passenger civil tiltrotor. The variable diameter tiltrotor (VDTR) is a Sikorsky concept aimed at improving tiltrotor hover and cruise performance currently limited by disk loading that is much higher in hover than conventional helicopter, and much lower in cruise than turbo-prop systems. This paper describes the technical merits of using a VDTR on a SHCT aircraft. The focus will be the rotor design.

X-37 C-Sic CMC Control Surface Components Development [Status of the NASA/Boeing/USAF Orbital Vehicle and Related Efforts

NASA Technical Reports Server (NTRS)

Valentine, Peter G; Rivers, H. Kevin; Chen, Victor L.

2004-01-01

Carbon/Silicon-Carbide (C-Sic) ceramic matrix composite (CMC) flaperon and ruddervator control surface components are being developed for the X-37 Orbital Vehicle (OV). The results of the prior NASA LaRC led work, aimed at developing C-Sic flaperon and ruddervator components for the X-37, will be reviewed. The status of several on-going and/or planned NASA, USAF, and Boeing programs that will support the development of control surface components for the X-37 OV will also be reviewed. The overall design and development philosophy being employed to assemble a team(s) to develop both: (a) C-Sic hot structure control surface components for the X-37 OV, and (b) carbon-carbon (C-C) hot structure components (a risk-reduction backup option for the OV), will be presented.

Lessons learned from a health record bank start-up.

PubMed

Yasnoff, W A; Shortliffe, E H

2014-01-01

This article is part of a Focus Theme of METHODS of Information in Medicine on Health Record Banking. In late summer 2010, an organization was formed in greater Phoenix, Arizona (USA), to introduce a health record bank (HRB) in that community. The effort was initiated after market research and was aimed at engaging 200,000 individuals as members in the first year (5% of the population). It was also intended to evaluate a business model that was based on early adoption by consumers and physicians followed by additional revenue streams related to incremental services and secondary uses of clinical data, always with specific permission from individual members, each of whom controlled all access to his or her own data. To report on the details of the HRB experience in Phoenix, to describe the sources of problems that were experienced, and to identify lessons that need to be considered in future HRB ventures. We describe staffing for the HRB effort, the computational platform that was developed, the approach to marketing, the engagement of practicing physicians, and the governance model that was developed to guide the HRB design and implementation. Despite efforts to engage the physician community, limited consumer advertising, and a carefully considered financial strategy, the experiment failed due to insufficient enrollment of individual members. It was discontinued in April 2011. Although the major problem with this HRB project was undercapitalization, we believe this effort demonstrated that basic HRB accounts should be free for members and that physician engagement and participation are key elements in constructing an effective marketing channel. Local community governance is essential for trust, and the included population must be large enough to provide sufficient revenues to sustain the resource in the long term.

Binaural Fusion and Listening Effort in Children Who Use Bilateral Cochlear Implants: A Psychoacoustic and Pupillometric Study

PubMed Central

Steel, Morrison M.; Papsin, Blake C.; Gordon, Karen A.

2015-01-01

Bilateral cochlear implants aim to provide hearing to both ears for children who are deaf and promote binaural/spatial hearing. Benefits are limited by mismatched devices and unilaterally-driven development which could compromise the normal integration of left and right ear input. We thus asked whether children hear a fused image (ie. 1 vs 2 sounds) from their bilateral implants and if this “binaural fusion” reduces listening effort. Binaural fusion was assessed by asking 25 deaf children with cochlear implants and 24 peers with normal hearing whether they heard one or two sounds when listening to bilaterally presented acoustic click-trains/electric pulses (250 Hz trains of 36 ms presented at 1 Hz). Reaction times and pupillary changes were recorded simultaneously to measure listening effort. Bilaterally implanted children heard one image of bilateral input less frequently than normal hearing peers, particularly when intensity levels on each side were balanced. Binaural fusion declined as brainstem asymmetries increased and age at implantation decreased. Children implanted later had access to acoustic input prior to implantation due to progressive deterioration of hearing. Increases in both pupil diameter and reaction time occurred as perception of binaural fusion decreased. Results indicate that, without binaural level cues, children have difficulty fusing input from their bilateral implants to perceive one sound which costs them increased listening effort. Brainstem asymmetries exacerbate this issue. By contrast, later implantation, reflecting longer access to bilateral acoustic hearing, may have supported development of auditory pathways underlying binaural fusion. Improved integration of bilateral cochlear implant signals for children is required to improve their binaural hearing. PMID:25668423