NASA Technical Reports Server (NTRS)
Zhang, Ping; Imhoff, Marc L.; Bounoua, Lahouri; Wolfe, Robert E.
2011-01-01
Impervious surface area (ISA) from the National Land Cover Database (NLCD) 2001 and land surface temperature (LST) from MODIS averaged over three annual cycles (2003-2005) are used in a spatial analysis to assess the urban heat island (UHI) signature and its relationship to settlement size and shape, development intensity distribution, and land cover composition for 42 urban settlements embedded in forest biomes in the Northeastern United States. Development intensity zones, based on percent ISA, are defined for each urban area emanating outward from the urban core to nearby rural areas and are used to stratify land surface temperature. The stratification is further constrained by biome type and elevation to insure objective intercomparisons between urban zones within an urban settlement and between settlements. Stratification based on ISA allows the definition of hierarchically ordered urban zones that are consistent across urban settlements and scales. In addition to the surrounding ecological context, we find that the settlement size and shape as well as the development intensity distribution significantly influence the amplitude of summer daytime UHI. Within the Northeastern US temperate broadleaf mixed forest, UHI magnitude is positively related to the logarithm of the urban area size. Our study indicates that for similar urban area sizes, the development intensity distribution is one of the major drivers of UHI. In addition to urban area size and development intensity distribution, this analysis shows that both the shape of the urban area and the land cover composition in the surrounding rural area play an important role in modulating the UHI magnitude in different urban settlements. Our results indicate that remotely sensed urban area size and shape as well as the development intensity distribution influence UHI amplitude across regional scales.
Multi-keV X-ray area source intensity at SGII laser facility
NASA Astrophysics Data System (ADS)
Wang, Rui-rong; An, Hong-hai; Xie, Zhi-yong; Wang, Wei
2018-05-01
Experiments for investigating the feasibility of multi-keV backlighters for several different metallic foil targets were performed at the Shenguang II (SGII) laser facility in China. Emission spectra in the energy range of 1.65-7.0 keV were measured with an elliptically bent crystal spectrometer, and the X-ray source size was measured with a pinhole camera. The X-ray intensity near 4.75 keV and the X-ray source size for titanium targets at different laser intensity irradiances were studied. By adjusting the total laser energy at a fixed focal spot size, laser intensity in the range of 1.5-5.0 × 1015 W/cm2, was achieved. The results show that the line emission intensity near 4.75 keV and the X-ray source size are dependent on the laser intensity and increase as the laser intensity increases. However, an observed "peak" in the X-ray intensity near 4.75 keV occurs at an irradiance of 4.0 × 1015 W/cm2. For the employed experimental conditions, it was confirmed that the laser intensity could play a significant role in the development of an efficient multi-keV X-ray source. The experimental results for titanium indicate that the production of a large (˜350 μm in diameter) intense backlighter source of multi-keV X-rays is feasible at the SGII facility.
NASA Technical Reports Server (NTRS)
Hess, C. F.; Smart, A. E.; Espinosa, V. E.
1985-01-01
An instrument to measure the size and velocity of droplets was developed. The instrument uses one of two techniques, as appropriate. In the first technique two small laser beams of one color identify the center of a larger laser beam of a different color. This defines a region of almost uniform intensity where the light scattered by the individual droplets can be related to their size. The first technique uses the visibility of a Doppler burst and validates it against the peak intensity of the signal's pedestal. Results are presented for monodisperse, bimodal, trimodal, and polydisperse sprays produced by the Berglund-Liu droplet generator and a pressure nozzle. Size distributions of a given spray obtained using three different size ranges show excellent self-consistency in the overlapping region. Measurements of sprays of known characteristics exhibit errors in the order of 10%. The principles of operation and design criteria of the instrument are discussed in great detail.
Establishing intensively cultured hybrid poplar plantations for fuel and fiber.
Edward Hansen; Lincoln Moore; Daniel Netzer; Michael Ostry; Howard Phipps; Jaroslav Zavitkovski
1983-01-01
This paper describes a step-by-step procedure for establishing commercial size intensively cultured plantations of hybrid poplar and summarizes the state-of-knowledge as developed during 10 years of field research at Rhinelander, Wisconsin.
Hare, J Daniel
1980-01-01
Burr size is the major factor affecting variation in the intensity of predation by two species of insect on the seeds of the cocklebur, Xanthium strumarium. Mean burr size varied among 10 adjacent local populations studied over three years, as did intensity of seed predation. Seed predation was more intense in populations with low mean burr length and declined linearly with increasing burr length under field and experimental conditions. Seed predation thus is a selective factor influencing the evolution of both burr size and correlated protective characteristics such as burr spine length and wall thickness. As in some other plants, morphological rather than chemical features appear to pose the major barrier to attack by host-specific seed predators. The advantage of more highly developed tissues protecting seeds may occur at the expense of total seed production.
The role of cavitation in liposome formation.
Richardson, Eric S; Pitt, William G; Woodbury, Dixon J
2007-12-15
Liposome size is a vital parameter of many quantitative biophysical studies. Sonication, or exposure to ultrasound, is used widely to manufacture artificial liposomes, yet little is known about the mechanism by which liposomes are affected by ultrasound. Cavitation, or the oscillation of small gas bubbles in a pressure-varying field, has been shown to be responsible for many biophysical effects of ultrasound on cells. In this study, we correlate the presence and type of cavitation with a decrease in liposome size. Aqueous lipid suspensions surrounding a hydrophone were exposed to various intensities of ultrasound and hydrostatic pressures before measuring their size distribution with dynamic light scattering. As expected, increasing ultrasound intensity at atmospheric pressure decreased the average liposome diameter. The presence of collapse cavitation was manifested in the acoustic spectrum at high ultrasonic intensities. Increasing hydrostatic pressure was shown to inhibit the presence of collapse cavitation. Collapse cavitation, however, did not correlate with decreases in liposome size, as changes in size still occurred when collapse cavitation was inhibited either by lowering ultrasound intensity or by increasing static pressure. We propose a mechanism whereby stable cavitation, another type of cavitation present in sound fields, causes fluid shearing of liposomes and reduction of liposome size. A mathematical model was developed based on the Rayleigh-Plesset equation of bubble dynamics and principles of acoustic microstreaming to estimate the shear field magnitude around an oscillating bubble. This model predicts the ultrasound intensities and pressures needed to create shear fields sufficient to cause liposome size change, and correlates well with our experimental data.
NASA Astrophysics Data System (ADS)
Nicchio, Matheus A.; Nogueira, Francisco C. C.; Balsamo, Fabrizio; Souza, Jorge A. B.; Carvalho, Bruno R. B. M.; Bezerra, Francisco H. R.
2018-02-01
In this work we describe the deformation mechanisms and processes that occurred during the evolution of cataclastic deformation bands developed in the feldspar-rich conglomerates of the Rio do Peixe Basin, NE Brazil. We studied bands with different deformation intensities, ranging from single cm-thick tabular bands to more evolved clustering zones. The chemical identification of cataclastic material within deformation bands was performed using compositional mapping in SEM images, EDX and XRD analyses. Deformation processes were identified by microstructural analysis and by the quantification of comminution intensity, performed using digital image processing. The deformation bands are internally non homogeneous and developed during five evolutionary stages: (1) moderate grain size reduction, grain rotation and grain border comminution; (2) intense grain size reduction with preferential feldspar fragmentation; (3) formation of subparallel C-type slip zones; (4) formation of S-type structures, generating S-C-like fabric; and (5) formation of C‧-type slip zones, generating well-developed foliation that resembles S-C-C‧-type structures in a ductile environment. Such deformation fabric is mostly imparted by the preferential alignment of intensely comminuted feldspar fragments along thin slip zones developed within deformation bands. These processes were purely mechanical (i.e., grain crushing and reorientation). No clays or fluids were involved in such processes.
Tropical cyclone fullness: A new concept for interpreting storm intensity
NASA Astrophysics Data System (ADS)
Guo, Xi; Tan, Zhe-Min
2017-05-01
Intensity and size are two crucial factors in determining the destructiveness of a tropical cyclone (TC), but little is known about the relationship between them because of a lack of observations. TC fullness, a new concept, is proposed to quantitatively measure the storm wind structure, which is defined as the ratio of the extent of the outer-core wind skirt to the outer-core size of the TC. TC intensity is more strongly correlated with fullness than with other measures comprising just a single size parameter. A scale is introduced to classify TCs into four categories based on TC fullness (FS1 to FS4). Regardless of the specific inner-core and outer-core size, the FS4 fullness structure is necessary for an intense TC's development, while category FS1 and FS2 TCs are generally weak. Most major TCs achieve FS4 fullness structure earlier and more frequently than nonmajor TCs. Rapidly increasing fullness favors the intensification of TC.
Norazmi-Lokman, Nor Hakim; Purser, G. J.; Patil, Jawahar G.
2016-01-01
In most livebearing fish, the gravid spot is an excellent marker to identify brooding females, however its use to predict progress of embryonic development, brood size, timing of parturition and overall reproductive potential of populations remain unexplored. Therefore, to understand these relationships, this study quantified visual attributes (intensity and size) of the gravid spot in relation to key internal development in Gambusia holbrooki. Observations show that the colour of the gravid spot arises from progressive melanisation on the surface of the ovarian sac at its hind margin, rather than melanisation of the developing embryos or the skin of the brooding mother. More importantly, the gravid spot intensity and size were closely linked with both developmental stages and clutch size, suggesting their reliable use as external surrogates of key internal developmental in the species. Using predictive consistency of the gravid spot, we also determined the effect of rearing temperature (23°C and 25°C) on gestation period and parturition behaviour. The results show that gestation period was significantly reduced (F = 364.58; df = 1,48; P˃0.05) at 25°C. However there was no significant difference in average number of fry parturated in the two temperature groups (P<0.05), reaffirming that gravid spot intensity is a reliable predictor of reproductive output. The parturition in the species occurred predominantly in the morning and in contrast to earlier reports, tails of the fry emerged first with a few exceptions of head-first, twin and premature births. This study demonstrates utility of the gravid spot for downstream reproductive investigations in a live-bearing fish both in the field and laboratory. The reproducibility of the relationships (intensity with both developmental stage and clutch size), imply that they are also relevant to wild populations that experience varying temperature climes and stressors, significant deviations of which may serve as indicators of environmental health and climate variability. PMID:26808521
Li, Meng; Zhang, Lu; Davé, Rajesh N; Bilgili, Ecevit
2016-04-01
As a drug-sparing approach in early development, vibratory milling has been used for the preparation of nanosuspensions of poorly water-soluble drugs. The aim of this study was to intensify this process through a systematic increase in vibration intensity and bead loading with the optimal bead size for faster production. Griseofulvin, a poorly water-soluble drug, was wet-milled using yttrium-stabilized zirconia beads with sizes ranging from 50 to 1500 μm at low power density (0.87 W/g). Then, this process was intensified with the optimal bead size by sequentially increasing vibration intensity and bead loading. Additional experiments with several bead sizes were performed at high power density (16 W/g), and the results were compared to those from wet stirred media milling. Laser diffraction, scanning electron microscopy, X-ray diffraction, differential scanning calorimetry, and dissolution tests were used for characterization. Results for the low power density indicated 800 μm as the optimal bead size which led to a median size of 545 nm with more than 10% of the drug particles greater than 1.8 μm albeit the fastest breakage. An increase in either vibration intensity or bead loading resulted in faster breakage. The most intensified process led to 90% of the particles being smaller than 300 nm. At the high power intensity, 400 μm beads were optimal, which enhanced griseofulvin dissolution significantly and signified the importance of bead size in view of the power density. Only the optimally intensified vibratory milling led to a comparable nanosuspension to that prepared by the stirred media milling.
Effects of multiple fires on the structure of southwestern Washington forests
Andrew N. Gray; Jerry F. Franklin
1997-01-01
Fire frequcncy, intensity, and size can influence the nature of forest development, with potentially profound effects on ecosystem processes and the abundance of native species. The effect of an intense wildfire and subsequent severe fires within a short period (reburns) on forest establishment, composition, and structure was examined in the 16,000 ha Siouxon Creek...
A source to deliver mesoscopic particles for laser plasma studies
NASA Astrophysics Data System (ADS)
Gopal, R.; Kumar, R.; Anand, M.; Kulkarni, A.; Singh, D. P.; Krishnan, S. R.; Sharma, V.; Krishnamurthy, M.
2017-02-01
Intense ultrashort laser produced plasmas are a source for high brightness, short burst of X-rays, electrons, and high energy ions. Laser energy absorption and its disbursement strongly depend on the laser parameters and also on the initial size and shape of the target. The ability to change the shape, size, and material composition of the matter that absorbs light is of paramount importance not only from a fundamental physics point of view but also for potentially developing laser plasma sources tailored for specific applications. The idea of preparing mesoscopic particles of desired size/shape and suspending them in vacuum for laser plasma acceleration is a sparsely explored domain. In the following report we outline the development of a delivery mechanism of microparticles into an effusive jet in vacuum for laser plasma studies. We characterise the device in terms of particle density, particle size distribution, and duration of operation under conditions suitable for laser plasma studies. We also present the first results of x-ray emission from micro crystals of boric acid that extends to 100 keV even under relatively mild intensities of 1016 W/cm2.
NASA Astrophysics Data System (ADS)
Baker, Patrick; Oborne, Lisa
2015-04-01
Large, high-intensity fires have direct and long-lasting effects on forest ecosystems and present a serious threat to human life and property. However, even within the most catastrophic fires there is important variability in local-scale intensity that has important ramifications for forest mortality and regeneration. Quantifying this variability is difficult due to the rarity of catastrophic fire events, the extreme conditions at the time of the fires, and their large spatial extent. Instead fire severity is typically measured or estimated from observed patterns of vegetation mortality; however, differences in species- and size-specific responses to fires often makes fire severity a poor proxy for fire intensity. We developed a statistical method using simple, plot-based measurements of individual tree mortality to simultaneously estimate plot-level fire intensity and species-specific mortality patterns as a function of tree size. We applied our approach to an area of forest burned in the catastrophic Black Saturday fires that occurred near Melbourne, Australia, in February 2009. Despite being the most devastating fire in the past 70 years and our plots being located in the area that experienced some of the most intense fires in the 350,000 ha fire complex, we found that the estimated fire intensity was highly variable at multiple spatial scales. All eight tree species in our study differed in their susceptibility to fire-induced mortality, particularly among the largest size classes. We also found that seedling height and species richness of the post-fire seedling communities were both positively correlated with fire intensity. Spatial variability in disturbance intensity has important, but poorly understood, consequences for the short- and long-term dynamics of forests in the wake of catastrophic wildfires. Our study provides a tool to estimate fire intensity after a fire has passed, allowing new opportunities for linking spatial variability in fire intensity to forest ecosystem dynamics.
NASA Astrophysics Data System (ADS)
Akins, Meredith L.; Luby-Phelps, Katherine; Mahendroo, Mala
2010-03-01
We use second harmonic generation (SHG) microscopy to assess changes in collagen structure of murine cervix during cervical remodeling of normal pregnancy and in a preterm birth model. Visual inspection of SHG images revealed substantial changes in collagen morphology throughout normal gestation. SHG images collected in both the forward and backward directions were analyzed quantitatively for changes in overall mean intensity, forward to backward intensity ratio, collagen fiber size, and porosity. Changes in mean SHG intensity and intensity ratio take place in early pregnancy, suggesting that submicroscopic changes in collagen fibril size and arrangement occur before macroscopic changes become evident. Fiber size progressively increased from early to late pregnancy, while pores between collagen fibers became larger and farther apart. Analysis of collagen features in premature cervical remodeling show that changes in collagen structure are dissimilar from normal remodeling. The ability to quantify multiple morphological features of collagen that characterize normal cervical remodeling and distinguish abnormal remodeling in preterm birth models supports future studies aimed at development of SHG endoscopic devices for clinical assessment of collagen changes during pregnancy in women and for predicting risk of preterm labor which occurs in 12.5% of all pregnancies.
Kooken, Wendy Carter; Eckhardt, Ann L; McNutt-Dungan, Marianne; Woods, Jonathan
Most academic-clinical partnerships are described as formal agreements between schools of nursing at research-intensive universities and large teaching hospitals. This article demonstrates less formal versions of academic-clinical partnerships established between a small, private liberal arts university school of nursing and 2 regional clinical agencies. In both exemplars, students, faculty, and staff contributed to evidence-based practice projects. Schools of nursing in non-research-intensive environments can develop right-size academic-clinical partnerships that are beneficial for all parties involved.
Du, Guo-Qing; Xue, Jing-Yi; Guo, Yanhui; Chen, Shuang; Du, Pei; Wu, Yan; Wang, Yu-Hang; Zong, Li-Qiu; Tian, Jia-Wei
2015-09-01
Proper evaluation of myocardial microvascular perfusion and assessment of infarct size is critical for clinicians. We have developed a novel computer-aided diagnosis (CAD) approach for myocardial contrast echocardiography (MCE) to measure myocardial perfusion and infarct size. Rabbits underwent 15 min of coronary occlusion followed by reperfusion (group I, n = 15) or 60 min of coronary occlusion followed by reperfusion (group II, n = 15). Myocardial contrast echocardiography was performed before and 7 d after ischemia/reperfusion, and images were analyzed with the CAD system on the basis of eliminating particle swarm optimization clustering analysis. The myocardium was quickly and accurately detected using contrast-enhanced images, myocardial perfusion was quantitatively calibrated and a color-coded map calibrated by contrast intensity and automatically produced by the CAD system was used to outline the infarction region. Calibrated contrast intensity was significantly lower in infarct regions than in non-infarct regions, allowing differentiation of abnormal and normal myocardial perfusion. Receiver operating characteristic curve analysis documented that -54-pixel contrast intensity was an optimal cutoff point for the identification of infarcted myocardium with a sensitivity of 95.45% and specificity of 87.50%. Infarct sizes obtained using myocardial perfusion defect analysis of original contrast images and the contrast intensity-based color-coded map in computerized images were compared with infarct sizes measured using triphenyltetrazolium chloride staining. Use of the proposed CAD approach provided observers with more information. The infarct sizes obtained with myocardial perfusion defect analysis, the contrast intensity-based color-coded map and triphenyltetrazolium chloride staining were 23.72 ± 8.41%, 21.77 ± 7.8% and 18.21 ± 4.40% (% left ventricle) respectively (p > 0.05), indicating that computerized myocardial contrast echocardiography can accurately measure infarct size. On the basis of the results, we believe the CAD method can quickly and automatically measure myocardial perfusion and infarct size and will, it is hoped, be very helpful in clinical therapeutics. Copyright © 2015 World Federation for Ultrasound in Medicine & Biology. Published by Elsevier Inc. All rights reserved.
Forbes, Andrew B; Akram, Muhammad; Pilcher, David; Cooper, Jamie; Bellomo, Rinaldo
2015-02-01
Cluster randomised crossover trials have been utilised in recent years in the health and social sciences. Methods for analysis have been proposed; however, for binary outcomes, these have received little assessment of their appropriateness. In addition, methods for determination of sample size are currently limited to balanced cluster sizes both between clusters and between periods within clusters. This article aims to extend this work to unbalanced situations and to evaluate the properties of a variety of methods for analysis of binary data, with a particular focus on the setting of potential trials of near-universal interventions in intensive care to reduce in-hospital mortality. We derive a formula for sample size estimation for unbalanced cluster sizes, and apply it to the intensive care setting to demonstrate the utility of the cluster crossover design. We conduct a numerical simulation of the design in the intensive care setting and for more general configurations, and we assess the performance of three cluster summary estimators and an individual-data estimator based on binomial-identity-link regression. For settings similar to the intensive care scenario involving large cluster sizes and small intra-cluster correlations, the sample size formulae developed and analysis methods investigated are found to be appropriate, with the unweighted cluster summary method performing well relative to the more optimal but more complex inverse-variance weighted method. More generally, we find that the unweighted and cluster-size-weighted summary methods perform well, with the relative efficiency of each largely determined systematically from the study design parameters. Performance of individual-data regression is adequate with small cluster sizes but becomes inefficient for large, unbalanced cluster sizes. When outcome prevalences are 6% or less and the within-cluster-within-period correlation is 0.05 or larger, all methods display sub-nominal confidence interval coverage, with the less prevalent the outcome the worse the coverage. As with all simulation studies, conclusions are limited to the configurations studied. We confined attention to detecting intervention effects on an absolute risk scale using marginal models and did not explore properties of binary random effects models. Cluster crossover designs with binary outcomes can be analysed using simple cluster summary methods, and sample size in unbalanced cluster size settings can be determined using relatively straightforward formulae. However, caution needs to be applied in situations with low prevalence outcomes and moderate to high intra-cluster correlations. © The Author(s) 2014.
Enhancement of fluorescence intensity by silicon particles and its size effect.
Saitow, Ken-ichi; Suemori, Hidemi; Tamamitsu, Hironori
2014-02-04
Fluorescence-intensity enhancement of dye molecules was investigated using silicon submicron particles as a function of the particle size. Silicon particles with a size of 500 nm gave an enhancement factor up to 180. Measurement of scattering spectra revealed that the localized electric field at the particle enhances the fluorescence intensity.
NASA Astrophysics Data System (ADS)
Liu, Xingxing; Sun, Youbin; Vandenberghe, Jef; Li, Ying; An, Zhisheng
2018-06-01
Sedimentary sequences that developed on river terraces have been widely investigated to reconstruct high-resolution palaeoclimatic changes since the last deglaciation. However, frequent changes in sedimentary facies make palaeoenvironmental interpretation of grain-size variations relatively complicated. In this paper, we employed multiple grain-size parameters to discriminate the sedimentary characteristics of aeolian and fluvial facies in the Dadiwan (DDW) section on the western Chinese Loess Plateau. We found that wind and fluvial dynamics have quite different impacts on the grain-size compositions, with distinctive imprints on the distribution pattern. By using a lognormal distribution fitting approach, two major grain-size components sensitive to aeolian and fluvial processes, respectively, were distinguished from the grain-size compositions of the DDW terrace deposits. The fine grain-size component (GSC2) represents mixing of long-distance aeolian and short-distance fluvial inputs, whilst the coarse grain-size component (GSC3) is mainly transported by wind from short-distance sources. Thus GSC3 can be used to infer the wind intensity. Grain-size variations reveal that the wind intensity experienced a stepwise shift from large-amplitude variations during the last deglaciation to small-amplitude oscillations in the Holocene, corresponding well to climate changes from regional to global context.
NASA Technical Reports Server (NTRS)
Vakhtin, Andrei; Krasnoperov, Lev
2011-01-01
An affordable technology designed to facilitate extensive global atmospheric aerosol measurements has been developed. This lightweight instrument is compatible with newly developed platforms such as tethered balloons, blimps, kites, and even disposable instruments such as dropsondes. This technology is based on detection of light scattered by aerosol particles where an optical layout is used to enhance the performance of the laboratory prototype instrument, which allows detection of smaller aerosol particles and improves the accuracy of aerosol particle size measurement. It has been determined that using focused illumination geometry without any apertures is advantageous over using the originally proposed collimated beam/slit geometry (that is supposed to produce uniform illumination over the beam cross-section). The illumination source is used more efficiently, which allows detection of smaller aerosol particles. Second, the obtained integral scattered light intensity measured for the particle can be corrected for the beam intensity profile inhomogeneity based on the measured beam intensity profile and measured particle location. The particle location (coordinates) in the illuminated sample volume is determined based on the information contained in the image frame. The procedure considerably improves the accuracy of determination of the aerosol particle size.
Wang, Qian; Zhang, Qionghua; Dzakpasu, Mawuli; Lian, Bin; Wu, Yaketon; Wang, Xiaochang C
2018-03-01
Stormwater particles washed from road-deposited sediments (RDS) are traditionally characterized as either turbidity or total suspended solids (TSS). Although these parameters are influenced by particle sizes, neither of them characterizes the particle size distribution (PSD), which is of great importance in pollutant entrainment and treatment performance. Therefore, the ratio of turbidity to TSS (Tur/TSS) is proposed and validated as a potential surrogate for the bulk PSD and quality of stormwater runoff. The results show an increasing trend of Tur/TSS with finer sizes of both RDS and stormwater runoff. Taking heavy metals (HMs, including Cu, Pb, Zn, Cr, and Ni) as typical pollutants in stormwater runoff, the concentrations (mg/kg) were found to vary significantly during rainfall events and tended to increase significantly with Tur/TSS. Therefore, Tur/TSS is a valid parameter to characterize the PSD and quality of stormwater. The high negative correlations between Tur/TSS and rainfall intensity demonstrate that stormwater with higher Tur/TSS generates under low intensity and, thus, characterizes small volume, finer sizes, weak settleability, greater mobility, and bioavailability. Conversely, stormwater with lower Tur/TSS generates under high intensity and, thus, characterizes large volume, coarser sizes, good settleability, low mobility, and bioavailability. These results highlight the need to control stormwater with high Tur/TSS. Moreover, Tur/TSS can aid the selection of stormwater control measures with appropriate detention storage, pollution loading, and removal effectiveness of particles.
Computational Process Modeling for Additive Manufacturing
NASA Technical Reports Server (NTRS)
Bagg, Stacey; Zhang, Wei
2014-01-01
Computational Process and Material Modeling of Powder Bed additive manufacturing of IN 718. Optimize material build parameters with reduced time and cost through modeling. Increase understanding of build properties. Increase reliability of builds. Decrease time to adoption of process for critical hardware. Potential to decrease post-build heat treatments. Conduct single-track and coupon builds at various build parameters. Record build parameter information and QM Meltpool data. Refine Applied Optimization powder bed AM process model using data. Report thermal modeling results. Conduct metallography of build samples. Calibrate STK models using metallography findings. Run STK models using AO thermal profiles and report STK modeling results. Validate modeling with additional build. Photodiode Intensity measurements highly linear with power input. Melt Pool Intensity highly correlated to Melt Pool Size. Melt Pool size and intensity increase with power. Applied Optimization will use data to develop powder bed additive manufacturing process model.
Tittler, Rebecca; Messier, Christian; Fall, Andrew
2012-06-01
To maintain healthy ecosystems, natural-disturbance-based management aims to minimize differences between unmanaged and managed landscapes. Two related approaches may help accomplish this goal, either applied together or in isolation: (1) concentrating anthropogenic disturbance through zoning (with protected areas and intensive management); and (2) emulating natural disturbances. The purpose of this paper is to examine the effects of these two approaches, applied both in isolation and in combination, on the structure of the forest landscape. To do so, we use a spatially explicit landscape simulation model on a large fire-dominated landscape in eastern Canada. Specifically, we examine the effects of (1) increasing the maximum size of logged stands (cutblocks) to better emulate the full range of fire sizes in a fire-dominated landscape, (2) increasing protected areas, and (3) adding aggregated or dispersed intensive wood production areas to the landscape in addition to protected areas (triad management). We focus on maximizing the amount and minimizing the fragmentation of old-growth forest and on reducing road construction. Increasing maximum cutblock size and adding protected areas led to reduced road construction, while the latter also resulted in less fragmentation and more old growth. Although protected areas led to reduced harvest volume, the addition of an intensive production zone (triad management) counterbalanced this loss and resulted in more old growth than equivalent scenarios with protected areas but no intensive production zone. However, we found no differences between aggregated and dispersed intensive wood production. Our results imply that differences between unmanaged and managed landscapes can be reduced by concentrating logging efforts through a combination of protected areas and intensive wood production, and by creating some larger cutblocks. We conclude that the forest industry and regulators should therefore seek to increase protected areas through triad management and consider increasing maximum cutblock size. These results add to a growing body of literature indicating that intensive management on a small part of the landscape may be better than less intensive management spread out over a much larger part of the landscape, whether this is in the context of forestry, agriculture, or urban development.
Removal intensity and tree size effects on harvesting cost and profitability
R. Kluender; D. Lortz; W. McCoy; B. Stokes; J. Klepac
1997-01-01
Sixteen stands were harvested at intensities (proportion of basal area removed) ranging from 0.27 to 1.00. Logging contractors used chain saws and rubber-tired skidders. Harvested sites were similar in slope and tree size. Harvest cost per hundred cubic feet of wood (CCF) was inversely related to harvest intensity and tree size. Harvesting profitability per CCF was...
NASA Astrophysics Data System (ADS)
Rezaei Ashtiani, Hamid Reza; Zarandooz, Roozbeh
2015-09-01
A 2D axisymmetric electro-thermo-mechanical finite element (FE) model is developed to investigate the effect of current intensity, welding time, and electrode tip diameter on temperature distributions and nugget size in resistance spot welding (RSW) process of Inconel 625 superalloy sheets using ABAQUS commercial software package. The coupled electro-thermal analysis and uncoupled thermal-mechanical analysis are used for modeling process. In order to improve accuracy of simulation, material properties including physical, thermal, and mechanical properties have been considered to be temperature dependent. The thickness and diameter of computed weld nuggets are compared with experimental results and good agreement is observed. So, FE model developed in this paper provides prediction of quality and shape of the weld nuggets and temperature distributions with variation of each process parameter, suitably. Utilizing this FE model assists in adjusting RSW parameters, so that expensive experimental process can be avoided. The results show that increasing welding time and current intensity lead to an increase in the nugget size and electrode indentation, whereas increasing electrode tip diameter decreases nugget size and electrode indentation.
Lee, Dong Ryul; Kim, Yun Hee; Kim, Dong A; Lee, Jung Ah; Hwang, Pil Woo; Lee, Min Jin; You, Sung Hyun
2014-01-01
In children with cerebral palsy (CP), the never-learned-to-use (NLTU) effect and underutilization suppress the normal development of cortical plasticity in the paretic limb, which further inhibits its functional use and increases associated muscle weakness. To highlight the effects of a novel comprehensive hand repetitive intensive strengthening training system on neuroplastic changes associated with upper extremity (UE) muscle strength and motor performance in children with spastic hemiplegic CP. Two children with spastic hemiplegic CP were recruited. Intervention with the comprehensive hand repetitive intensive strengthening training system was provided for 60 min a day, three times a week, for 10 weeks. Neuroplastic changes, muscle size, strength, and associated motor function were measured using functional magnetic resonance imaging (MRI), ultrasound imaging, and standardized motor tests, respectively. The functional MRI data showed that the comprehensive hand repetitive intensive strengthening training intervention produced measurable neuroplastic changes in the neural substrates associated with motor control and learning. These neuroplastic changes were associated with increased muscle size, strength and motor function. These results provide compelling evidence of neuroplastic changes and associated improvements in muscle size and motor function following innovative upper extremity strengthening exercise.
The scaling of urban surface water abundance and impairment with city size
NASA Astrophysics Data System (ADS)
Steele, M. K.
2018-03-01
Urbanization alters surface water compared to nonurban landscapes, yet little is known regarding how basic aquatic ecosystem characteristics, such as the abundance and impairment of surface water, differ with population size or regional context. This study examined the abundance, scaling, and impairment of surface water by quantifying the stream length, water body area, and impaired stream length for 3520 cities in the United States with populations from 2500 to 18 million. Stream length, water body area, and impaired stream length were quantified using the National Hydrography Dataset and the EPA's 303(d) list. These metrics were scaled with population and city area using single and piecewise power-law models and related to biophysical factors (precipitation, topography) and land cover. Results show that abundance of stream length and water body area in cities actually increases with city area; however, the per person abundance decreases with population size. Relative to population, impaired stream length did not increase until city populations were > 25,000 people, then scaled linearly with population. Some variation in abundance and impairment was explained by biophysical context and land cover. Development intensity correlated with stream density and impairment; however, those relationships depended on the orientation of the land covers. When high intensity development occupied the local elevation highs (+ 15 m) and undeveloped land the elevation lows, the percentage of impaired streams was less than the opposite land cover orientation (- 15 m) or very flat land. These results show that surface water abundance and impairment across contiguous US cities are influenced by city size and by biophysical setting interacting with land cover intensity.
Coulomb explosion of hydrogen clusters irradiated by an ultrashort intense laser pulse
DOE Office of Scientific and Technical Information (OSTI.GOV)
Li Hongyu; Liu Jiansheng; Wang Cheng
The explosion dynamics of hydrogen clusters driven by an ultrashort intense laser pulse has been analyzed analytically and numerically by employing a simplified Coulomb explosion model. The dependence of average and maximum proton kinetic energy on cluster size, pulse duration, and laser intensity has been investigated respectively. The existence of an optimum cluster size allows the proton energy to reach the maximum when the cluster size matches with the intensity and the duration of the laser pulse. In order to explain our experimental results such as the measured proton energy spectrum and the saturation effect of proton energy, the effectsmore » of cluster size distribution as well as the laser intensity distribution on the focus spot should be considered. A good agreement between them is obtained.« less
Coulomb explosion of hydrogen clusters irradiated by an ultrashort intense laser pulse
NASA Astrophysics Data System (ADS)
Li, Hongyu; Liu, Jiansheng; Wang, Cheng; Ni, Guoquan; Li, Ruxin; Xu, Zhizhan
2006-08-01
The explosion dynamics of hydrogen clusters driven by an ultrashort intense laser pulse has been analyzed analytically and numerically by employing a simplified Coulomb explosion model. The dependence of average and maximum proton kinetic energy on cluster size, pulse duration, and laser intensity has been investigated respectively. The existence of an optimum cluster size allows the proton energy to reach the maximum when the cluster size matches with the intensity and the duration of the laser pulse. In order to explain our experimental results such as the measured proton energy spectrum and the saturation effect of proton energy, the effects of cluster size distribution as well as the laser intensity distribution on the focus spot should be considered. A good agreement between them is obtained.
Tools to Improve the Accuracy of Kidney Stone Sizing with Ultrasound
Dunmire, Barbrina; Hsi, Ryan S.; Cunitz, Bryan W.; Paun, Marla; Bailey, Michael R.; Sorensen, Mathew D.; Harper, Jonathan D.
2015-01-01
Abstract Purpose: Ultrasound (US) overestimates stone size when compared with CT. The purpose of this work was to evaluate the overestimation of stone size with US in an in vitro water bath model and investigate methods to reduce overestimation. Materials and Methods: Ten human stones (3–12 mm) were measured using B-mode (brightness mode) US by a sonographer blinded to the true stone size. Images were captured and compared using both a commercial US machine and software-based research US device. Image gain was adjusted between moderate and high stone intensities, and the transducer-to-stone depth was varied from 6 to 10 cm. A computerized stone-sizing program was developed to outline the stone width based on a grayscale intensity threshold. Results: Overestimation with the commercial device increased with both gain and depth. Average overestimation at moderate and high gain was 1.9±0.8 and 2.1±0.9 mm, respectively (p=0.6). Overestimation increased an average of 22% with an every 2-cm increase in depth (p=0.02). Overestimation using the research device was 1.5±0.9 mm and did not vary with depth (p=0.28). Overestimation could be reduced to 0.02±1.1 mm (p<0.001) with the computerized stone-sizing program. However, a standardized threshold consistent across depth, system, or system settings could not be resolved. Conclusion: Stone size is consistently overestimated with US. Overestimation increased with increasing depth and gain using the commercial machine. Overestimation was reduced and did not vary with depth, using the software-based US device. The computerized stone-sizing program shows the potential to reduce overestimation by implementing a grayscale intensity threshold for defining the stone size. More work is needed to standardize the approach, but if successful, such an approach could significantly improve stone-sizing accuracy and lead to automation of stone sizing. PMID:25105243
Alaoui, I
2003-01-01
Neonatal and pediatric intensive care poses a major challenge in developing countries where the socio-economic level is low and health care resources are limited. Given the large size of the pediatric population as well as of great socio-cultural and symbolic importance of the child, there is a natural, compelling need for management of serious diseases in newborns and infants. The lack of timely disease prevention and treatment accounts in part for the frequency and severity of cases. Thus the status of intensive care units can exist in this setting is a pertinent question. The purpose of this study was to attempt to answer this question by surveying neonatal and pediatric care in developing countries based on experience in Morocco over the last 25 years.
Arnup, Sarah J; McKenzie, Joanne E; Pilcher, David; Bellomo, Rinaldo; Forbes, Andrew B
2018-06-01
The cluster randomised crossover (CRXO) design provides an opportunity to conduct randomised controlled trials to evaluate low risk interventions in the intensive care setting. Our aim is to provide a tutorial on how to perform a sample size calculation for a CRXO trial, focusing on the meaning of the elements required for the calculations, with application to intensive care trials. We use all-cause in-hospital mortality from the Australian and New Zealand Intensive Care Society Adult Patient Database clinical registry to illustrate the sample size calculations. We show sample size calculations for a two-intervention, two 12-month period, cross-sectional CRXO trial. We provide the formulae, and examples of their use, to determine the number of intensive care units required to detect a risk ratio (RR) with a designated level of power between two interventions for trials in which the elements required for sample size calculations remain constant across all ICUs (unstratified design); and in which there are distinct groups (strata) of ICUs that differ importantly in the elements required for sample size calculations (stratified design). The CRXO design markedly reduces the sample size requirement compared with the parallel-group, cluster randomised design for the example cases. The stratified design further reduces the sample size requirement compared with the unstratified design. The CRXO design enables the evaluation of routinely used interventions that can bring about small, but important, improvements in patient care in the intensive care setting.
NASA Astrophysics Data System (ADS)
Zhu, Xiaotong; Li, Qingqing; Yu, Jinhua; Wu, Dan; Yao, Kai
2018-05-01
The geometric characteristics of tropical cyclone (TC) eyes before landfall in South China are examined using ground-based radar reflectivity. It is found that the median and mean eye area decrease with TC intensity, except for the severe typhoon category, and the eye size increases with height. The increasing rate of eye size is relatively greater in upper layers. Moreover, the ratio of eye size change in the vertical direction does not correlate with TC intensity. No relationship is presented between the ratio of eye size change in the vertical direction and the vertical wind shear. No relationship between the vertical change in eye size and the eye size at a certain level is found, inconsistent with other studies. No relationship exists between the vertical change in eye size and the intensity tendency. The eye roundness values range mainly from 0.5 to 0.7, and more intense TCs generally have eyes that are more circular.
Dependence of Raman Spectral Intensity on Crystal Size in Organic Nano Energetics.
Patel, Rajen B; Stepanov, Victor; Qiu, Hongwei
2016-08-01
Raman spectra for various nitramine energetic compounds were investigated as a function of crystal size at the nanoscale regime. In the case of 2,4,6,8,10,12-hexanitro-2,4,6,8,10,12-hexaazaisowurtzitane (CL-20), there was a linear relationship between intensity of Raman spectra and crystal size. Notably, the Raman modes between 120 cm(-1) and 220 cm(-1) were especially affected, and at the smallest crystal size, were completely eliminated. The Raman spectral intensity of octahydro-1,3,5,7-tetranitro-1,3,5,7-tetrazocine (HMX), like that of CL-20's, depended linearly on crystal size. The Raman spectral intensity of 1,3,5-trinitroperhydro-1,3,5-triazine (RDX), however, was not observably changed by crystal size. A non-nitramine explosive compound, 2,4,6-triamino-1,3,5- trinitrobenzene (TATB), was also investigated. Its spectral intensity was also found to correlate linearly with crystal size, although substantially less so than that of HMX and CL-20. To explain the observed trends, it is hypothesized that disordered molecular arrangement, originating from the crystal surface, may be responsible. In particular, it appears that the thickness of the disordered surface layer is dependent on molecular characteristics, including size and conformational flexibility. Furthermore, as the mean crystal size decreases, the volume fraction of disordered molecules within a specimen increases, consequently, weakening the Raman intensity. These results could have practical benefit for allowing the facile monitoring of crystal size during manufacturing. Finally, these findings could lead to deep insights into the general structure of the surface of crystals. © The Author(s) 2016.
The Dugdale model for the compact specimen
NASA Technical Reports Server (NTRS)
Mall, S.; Newman, J. C., Jr.
1983-01-01
Plastic zone size and crack tip opening displacement (CTOD) equations were developed. Boundary collocation analyses were used to analyze the compact specimen subjected to various loading conditions (pin loads, concentrated forces, and uniform pressure acting on the crack surface). Stress intensity factor and crack surface displacement equations for some of these loadings were developed and used to obtain the Dugdale model. The results from the equations for plastic zone size and CTOD agreed well with numerical values calculated by Terada for crack length to width ratios greater than 0.4.
NASA Astrophysics Data System (ADS)
Castagno, K. A.; Ruehr, S. A.; Donnelly, J. P.; Woodruff, J. D.
2017-12-01
Coastal populations have grown increasingly susceptible to the impacts of tropical cyclone events as they grow in size, wealth, and infrastructure. Changes in tropical cyclone frequency and intensity, augmented by a changing climate, pose an increasing threat of property damage and loss of life. Reconstructions of intense-hurricane landfalls from a series of southeastern New England sediment cores identify a series of events spanning the past 2,000 years. Though the frequency of these landfalls is well constrained, the intensity of these storms, particularly those for which no historical record exists, is not. This study analyzes the grain-size distribution of major storm event beds along a transect of sediment cores from a kettle pond in Falmouth, MA. The grain-size distribution of each event is determined using an image processing, size, and shape analyzer. The depositional patterns and changes in grain-size distribution in these fine-grained systems may both spatially and temporally reveal characteristics of both storm intensity and the nature of sediment deposition. An inverse-modeling technique using this kind of grain-size analysis to determine past storm intensity has been explored in back-barrier lagoon systems in the Caribbean, but limited research has assessed its utility to assess deposits from back-barrier ponds in the northeastern United States. Increases in hurricane intensity may be closely tied to increases in sea surface temperature. As such, research into these prehistoric intervals of increased frequency and/or intensity provides important insight into the current and future hurricane risks facing coastal communities in New England.
Nanofabrication by advanced electron microscopy using intense and focused beam∗.
Furuya, Kazuo
2008-01-01
The nanogrowth and nanofabrication of solid substances using an intense and focused electron beam are reviewed in terms of the application of scanning and transmission electron microscopy (SEM, TEM and STEM) to control the size, position and structure of nanomaterials. The first example discussed is the growth of freestanding nanotrees on insulator substrates by TEM. The growth process of the nanotrees was observed in situ and analyzed by high-resolution TEM (HRTEM) and was mainly controlled by the intensity of the electron beam. The second example is position- and size-controlled nanofabrication by STEM using a focused electron beam. The diameters of the nanostructures grown ranged from 4 to 20 nm depending on the size of the electron beam. Magnetic nanostructures were also obtained using an iron-containing precursor gas, Fe(CO) 5 . The freestanding iron nanoantennas were examined by electron holography. The magnetic field was observed to leak from the nanostructure body which appeared to act as a 'nanomagnet'. The third example described is the effect of a vacuum on the size and growth process of fabricated nanodots containing W in an ultrahigh-vacuum field-emission TEM (UHV-FE-TEM). The size of the dots can be controlled by changing the dose of electrons and the partial pressure of the precursor. The smallest particle size obtained was about 1.5 nm in diameter, which is the smallest size reported using this method. Finally, the importance of a smaller probe and a higher electron-beam current with atomic resolution is emphasized and an attempt to develop an ultrahigh-vacuum spherical aberration corrected STEM (Cs-corrected STEM) at NIMS is reported.
Nanofabrication by advanced electron microscopy using intense and focused beam∗
Furuya, Kazuo
2008-01-01
The nanogrowth and nanofabrication of solid substances using an intense and focused electron beam are reviewed in terms of the application of scanning and transmission electron microscopy (SEM, TEM and STEM) to control the size, position and structure of nanomaterials. The first example discussed is the growth of freestanding nanotrees on insulator substrates by TEM. The growth process of the nanotrees was observed in situ and analyzed by high-resolution TEM (HRTEM) and was mainly controlled by the intensity of the electron beam. The second example is position- and size-controlled nanofabrication by STEM using a focused electron beam. The diameters of the nanostructures grown ranged from 4 to 20 nm depending on the size of the electron beam. Magnetic nanostructures were also obtained using an iron-containing precursor gas, Fe(CO)5. The freestanding iron nanoantennas were examined by electron holography. The magnetic field was observed to leak from the nanostructure body which appeared to act as a ‘nanomagnet’. The third example described is the effect of a vacuum on the size and growth process of fabricated nanodots containing W in an ultrahigh-vacuum field-emission TEM (UHV-FE-TEM). The size of the dots can be controlled by changing the dose of electrons and the partial pressure of the precursor. The smallest particle size obtained was about 1.5 nm in diameter, which is the smallest size reported using this method. Finally, the importance of a smaller probe and a higher electron-beam current with atomic resolution is emphasized and an attempt to develop an ultrahigh-vacuum spherical aberration corrected STEM (Cs-corrected STEM) at NIMS is reported. PMID:27877936
Short-Term Space-Use Patterns of Translocated Mojave Desert Tortoise in Southern California
Farnsworth, Matthew L.; Dickson, Brett G.; Zachmann, Luke J.; Hegeman, Ericka E.; Cangelosi, Amanda R.; Jackson, Thomas G.; Scheib, Amanda F.
2015-01-01
Increasingly, renewable energy comprises a larger share of global energy production. Across the western United States, public lands are being developed to support renewable energy production. Where there are conflicts with threatened or endangered species, translocation can be used in an attempt to mitigate negative effects. For the threatened Mojave desert tortoise (Gopherus agassizii), we sought to compare habitat- and space-use patterns between short-distance translocated, resident, and control groups. We tested for differences in home range size based on utilization distributions and used linear mixed-effects models to compare space-use intensity, while controlling for demographic and environmental variables. In addition, we examined mean movement distances as well as home range overlap between years and for male and female tortoises in each study group. During the first active season post-translocation, home range size was greater and space-use intensity was lower for translocated tortoises than resident and control groups. These patterns were not present in the second season. In both years, there was no difference in home range size or space-use intensity between control and resident groups. Translocation typically resulted in one active season of questing followed by a second active season characterized by space-use patterns that were indistinguishable from control tortoises. Across both years, the number of times a tortoise was found in a burrow was positively related to greater space-use intensity. Minimizing the time required for translocated tortoises to exhibit patterns similar to non-translocated individuals may have strong implications for conservation by reducing exposure to adverse environmental conditions and predation. With ongoing development, our results can be used to guide future efforts aimed at understanding how translocation strategies influence patterns of animal space use. PMID:26352691
Short-Term Space-Use Patterns of Translocated Mojave Desert Tortoise in Southern California.
Farnsworth, Matthew L; Dickson, Brett G; Zachmann, Luke J; Hegeman, Ericka E; Cangelosi, Amanda R; Jackson, Thomas G; Scheib, Amanda F
2015-01-01
Increasingly, renewable energy comprises a larger share of global energy production. Across the western United States, public lands are being developed to support renewable energy production. Where there are conflicts with threatened or endangered species, translocation can be used in an attempt to mitigate negative effects. For the threatened Mojave desert tortoise (Gopherus agassizii), we sought to compare habitat- and space-use patterns between short-distance translocated, resident, and control groups. We tested for differences in home range size based on utilization distributions and used linear mixed-effects models to compare space-use intensity, while controlling for demographic and environmental variables. In addition, we examined mean movement distances as well as home range overlap between years and for male and female tortoises in each study group. During the first active season post-translocation, home range size was greater and space-use intensity was lower for translocated tortoises than resident and control groups. These patterns were not present in the second season. In both years, there was no difference in home range size or space-use intensity between control and resident groups. Translocation typically resulted in one active season of questing followed by a second active season characterized by space-use patterns that were indistinguishable from control tortoises. Across both years, the number of times a tortoise was found in a burrow was positively related to greater space-use intensity. Minimizing the time required for translocated tortoises to exhibit patterns similar to non-translocated individuals may have strong implications for conservation by reducing exposure to adverse environmental conditions and predation. With ongoing development, our results can be used to guide future efforts aimed at understanding how translocation strategies influence patterns of animal space use.
NASA Astrophysics Data System (ADS)
Ferdous, Nazneen; Bhat, Chandra R.
2013-01-01
This paper proposes and estimates a spatial panel ordered-response probit model with temporal autoregressive error terms to analyze changes in urban land development intensity levels over time. Such a model structure maintains a close linkage between the land owner's decision (unobserved to the analyst) and the land development intensity level (observed by the analyst) and accommodates spatial interactions between land owners that lead to spatial spillover effects. In addition, the model structure incorporates spatial heterogeneity as well as spatial heteroscedasticity. The resulting model is estimated using a composite marginal likelihood (CML) approach that does not require any simulation machinery and that can be applied to data sets of any size. A simulation exercise indicates that the CML approach recovers the model parameters very well, even in the presence of high spatial and temporal dependence. In addition, the simulation results demonstrate that ignoring spatial dependency and spatial heterogeneity when both are actually present will lead to bias in parameter estimation. A demonstration exercise applies the proposed model to examine urban land development intensity levels using parcel-level data from Austin, Texas.
Mean turbulence statistics in boundary layers over high-porosity foams
NASA Astrophysics Data System (ADS)
Efstathiou, Christoph; Luhar, Mitul
2018-04-01
This paper reports turbulent boundary layer measurements made over open-cell reticulated foams with varying pore size and thickness, but constant porosity ($\\epsilon \\approx 0.97$). The foams were flush-mounted into a cutout on a flat plate. A Laser Doppler Velocimeter (LDV) was used to measure mean streamwise velocity and turbulence intensity immediately upstream of the porous section, and at multiple measurement stations along the porous substrate. The friction Reynolds number upstream of the porous section was $Re_\\tau \\approx 1690$. For all but the thickest foam tested, the internal boundary layer was fully developed by $<10 \\delta$ downstream from the porous transition, where $\\delta$ is the boundary layer thickness. Fully developed mean velocity profiles showed the presence of a substantial slip velocity at the porous interface ($>30\\%$ of the free stream velocity) and a mean velocity deficit relative to the canonical smooth-wall profile further from the wall. While the magnitude of the mean velocity deficit increased with average pore size, the slip velocity remained approximately constant. Fits to the mean velocity profile suggest that the logarithmic region is shifted relative to a smooth wall, and that this shift increases with pore size until it becomes comparable to substrate thickness $h$. For all foams, the turbulence intensity was found to be elevated further into the boundary layer to $y/ \\delta \\approx 0.2$. An outer peak in intensity was also evident for the largest pore sizes. Velocity spectra indicate that this outer peak is associated with large-scale structures resembling Kelvin-Helmholtz vortices that have streamwise length scale $2\\delta-4\\delta$. Skewness profiles suggest that these large-scale structures may have an amplitude-modulating effect on the interfacial turbulence.
ERIC Educational Resources Information Center
Zhang, Xuesong; Dorn, Bradley
2012-01-01
Agile development has received increasing interest both in industry and academia due to its benefits in developing software quickly, meeting customer needs, and keeping pace with the rapidly changing requirements. However, agile practices and scrum in particular have been mainly tested in mid- to large-size projects. In this paper, we present…
NASA Astrophysics Data System (ADS)
Loisel, G.; Lake, P.; Gard, P.; Dunham, G.; Nielsen-Weber, L.; Wu, M.; Norris, E.
2016-11-01
At Sandia National Laboratories, the x-ray generator Manson source model 5 was upgraded from 10 to 25 kV. The purpose of the upgrade is to drive higher characteristics photon energies with higher throughput. In this work we present characterization studies for the source size and the x-ray intensity when varying the source voltage for a series of K-, L-, and M-shell lines emitted from Al, Y, and Au elements composing the anode. We used a 2-pinhole camera to measure the source size and an energy dispersive detector to monitor the spectral content and intensity of the x-ray source. As the voltage increases, the source size is significantly reduced and line intensity is increased for the three materials. We can take advantage of the smaller source size and higher source throughput to effectively calibrate the suite of Z Pulsed Power Facility crystal spectrometers.
Large-Scale Compute-Intensive Analysis via a Combined In-situ and Co-scheduling Workflow Approach
DOE Office of Scientific and Technical Information (OSTI.GOV)
Messer, Bronson; Sewell, Christopher; Heitmann, Katrin
2015-01-01
Large-scale simulations can produce tens of terabytes of data per analysis cycle, complicating and limiting the efficiency of workflows. Traditionally, outputs are stored on the file system and analyzed in post-processing. With the rapidly increasing size and complexity of simulations, this approach faces an uncertain future. Trending techniques consist of performing the analysis in situ, utilizing the same resources as the simulation, and/or off-loading subsets of the data to a compute-intensive analysis system. We introduce an analysis framework developed for HACC, a cosmological N-body code, that uses both in situ and co-scheduling approaches for handling Petabyte-size outputs. An initial inmore » situ step is used to reduce the amount of data to be analyzed, and to separate out the data-intensive tasks handled off-line. The analysis routines are implemented using the PISTON/VTK-m framework, allowing a single implementation of an algorithm that simultaneously targets a variety of GPU, multi-core, and many-core architectures.« less
NASA Astrophysics Data System (ADS)
Toosi, E. R.; Quigley, M.; Kravchenko, A. N.
2014-12-01
It has been reported that conversion of intensively cultivated lands to less disturbed systems enhances soil OM storage capacity, primarily through OM stabilization in macroaggregates. We hypothesized that the potential for OM stabilization inside macro-aggregates is influenced by presence and abundance of intra-aggregate pores. Pores determine microbial access to OM and regulate diffusion of solution/gases within aggregates which drives microbial functioning. We investigated the influence of longterm disturbance intensity on soil OM composition and its relation to pore size distribution within macroaggregates. We used quantitative FTIR to determine OM decomposition status and X-ray micro-tomography to assess pore size distribution in macroaggregates as affected by management and landuse. Macroaggregates 4-6 mm in size where selected from topsoil under long term conventional tillage (CT), cover-crop (CC), and native succession vegetation (NS) treatments at Kellogg Biological Station, Michigan. Comparison of main soil OM functional groups suggested that with increasing disturbance intensity, the proportion of aromatic and carboxylic/carbohydrates associated compounds increased and it was concomitant with a decrease in the proportion of aliphatic associated compounds and lignin derivatives. Further, FTIR-based decomposition indices revealed that overall decomposition status of macroaggregates followed the pattern of CT > CC ≈ NS. X-ray micro-tomography findings suggested that greater OM decomposition within the macroaggregates was associated with i) greater percent of pores >13 micron in size within the aggregates, as well as ii) greater proportion of small to medium pores (13-110 micron). The results develop previous findings, suggesting that shift in landuse or management indirectly affects soil OM stabilization through alteration of pore size distribution within macroaggregates that itself, is coupled with OM decomposition status.
NASA Astrophysics Data System (ADS)
Kim, Nam Won; Shin, Mun-Ju; Lee, Jeong Eun
2016-04-01
The analysis of storm effects on floods is essential step for designing hydraulic structure and flood plain. There are previous studies for analyzing the relationship between the storm patterns and peak flow, flood volume and durations for various sizes of the catchments, but they are not enough to analyze the natural storm effects on flood responses quantitatively. This study suggests a novel method of quantitative analysis using unique factors extracted from the time series of storms and floods to investigate the relationship between natural storms and their corresponding flood responses. We used a distributed rainfall-runoff model of Grid based Rainfall-runoff Model (GRM) to generate the simulated flow and areal rainfall for 50 catchments in Republic of Korea size from 5.6 km2 to 1584.2 km2, which are including overlapped dependent catchments and non-overlapped independent catchments. The parameters of the GRM model were calibrated to get the good model performances of Nash-Sutcliffe efficiency. Then Flood-Intensity-Duration Curve (FIDC) and Rainfall-Intensity-Duration Curve (RIDC) were generated by Flood-Duration-Frequency and Intensity-Duration-Frequency methods respectively using the time series of hydrographs and hyetographs. Time of concentration developed for the Korea catchments was used as a consistent measure to extract the unique factors from the FIDC and RIDC over the different size of catchments. These unique factors for the storms and floods were analyzed against the different size of catchments to investigate the natural storm effects on floods. This method can be easily used to get the intuition of the natural storm effects with various patterns on flood responses. Acknowledgement This research was supported by a grant (11-TI-C06) from Advanced Water Management Research Program funded by Ministry of Land, Infrastructure and Transport of Korean government.
New model for high-power electromagnetic field instability in transparent media
DOE Office of Scientific and Technical Information (OSTI.GOV)
Gruzdev, V.E.; Libenson, M.N.
A model of high-power field instability is developed to describe local abrupt increasing of electromagnetic field intensity in transparent dielectric. Small local enhancement of the field amplitude is initiated by low-absorbing spherical inclusion which size is less than radiation wavelength. Exceeding threshold of optical bistability results in abrupt increasing of field amplitude in the defect that also leads to local increasing of field amplitude in the host material in the vicinity of the inclusion. Bearing in mind nonlinear dependence of refractive index of the host material on light intensity we develop a model to describe spreading of initial defect upmore » to size appropriate for the first resonant field mode to be formed. Increasing of refraction index due to nonlinear light-matter interaction and existence of high-Q eigenmodes of dielectric sphere can both cause positive feedback`s and result in field instability in the medium. Estimates are obtained of the threshold value of incident-field amplitude.« less
NASA Astrophysics Data System (ADS)
Block, Stephan; Fast, Björn Johansson; Lundgren, Anders; Zhdanov, Vladimir P.; Höök, Fredrik
2016-09-01
Biological nanoparticles (BNPs) are of high interest due to their key role in various biological processes and use as biomarkers. BNP size and composition are decisive for their functions, but simultaneous determination of both properties with high accuracy remains challenging. Optical microscopy allows precise determination of fluorescence/scattering intensity, but not the size of individual BNPs. The latter is better determined by tracking their random motion in bulk, but the limited illumination volume for tracking this motion impedes reliable intensity determination. Here, we show that by attaching BNPs to a supported lipid bilayer, subjecting them to hydrodynamic flows and tracking their motion via surface-sensitive optical imaging enable determination of their diffusion coefficients and flow-induced drifts, from which accurate quantification of both BNP size and emission intensity can be made. For vesicles, the accuracy of this approach is demonstrated by resolving the expected radius-squared dependence of their fluorescence intensity for radii down to 15 nm.
Enhanced laser-energy coupling to dense plasmas driven by recirculating electron currents
NASA Astrophysics Data System (ADS)
Gray, R. J.; Wilson, R.; King, M.; Williamson, S. D. R.; Dance, R. J.; Armstrong, C.; Brabetz, C.; Wagner, F.; Zielbauer, B.; Bagnoud, V.; Neely, D.; McKenna, P.
2018-03-01
The absorption of laser energy and dynamics of energetic electrons in dense plasma is fundamental to a range of intense laser-driven particle and radiation generation mechanisms. We measure the total reflected and scattered laser energy as a function of intensity, distinguishing between the influence of pulse energy and focal spot size on total energy absorption, in the interaction with thin foils. We confirm a previously published scaling of absorption with intensity by variation of laser pulse energy, but find a slower scaling when changing the focal spot size. 2D particle-in-cell simulations show that the measured differences arise due to energetic electrons recirculating within the target and undergoing multiple interactions with the laser pulse, which enhances absorption in the case of large focal spots. This effect is also shown to be dependent on the laser pulse duration, the target thickness and the electron beam divergence. The parameter space over which this absorption enhancement occurs is explored via an analytical model. The results impact our understanding of the fundamental physics of laser energy absorption in solids and thus the development of particle and radiation sources driven by intense laser–solid interactions.
Gravitational Effects on Reproduction, Growth, and Development of Mammals
NASA Technical Reports Server (NTRS)
Oyama, J.
1985-01-01
The broad objective of this research program is to determine the role which gravity plays in the growth and development of mammalian animals. Current studies are focused on the effects of graded hypergravitatinal field intensities on mice, rats and other small sized laboratory animals using the chronic centrifugation technique. They include studies on reproduction and prenatal and postnatel growth and development. Among the important questions addressed are: (1) what stage or stages in animal development are affected by hypergravity and what are the effects? (2) is there a minimum or critical body size for hypergravity to produce a significant effect on growth and development? (3) are there field intensity thresholds for the preceding questions? From analysis of the body masses at birth of rats conceived and allowed to undergo gestation under 2.1G and under normal gravity (1G), it was found that there was no significant difference between the two groups. Futhermore, their growth rates postnatally were the same until they reached a body mass of approximately 50 grams when the 2.1G group showed a significantly slower rate. Results from these studies support the conclusion that prenatal as well as the early postnatal stages of growth and development of the rat are refractory to hyper-G.
Kinner, David A.; Moody, John A.
2008-01-01
Multiple rainfall intensities were used in rainfall-simulation experiments designed to investigate the infiltration and runoff from 1-square-meter plots on burned hillslopes covered by an ash layer of varying thickness. The 1-square-meter plots were on north- and south-facing hillslopes in an area burned by the Overland fire northwest of Boulder near Jamestown on the Front Range of Colorado. A single-nozzle, wide-angle, multi-intensity rain simulator was developed to investigate the infiltration and runoff on steep (30- to 40-percent gradient) burned hillslopes covered with ash. The simulated rainfall was evaluated for spatial variability, drop size, and kinetic energy. Fourteen rainfall simulations, at three intensities (about 20 millimeters per hour [mm/h], 35 mm/h, and 50 mm/h), were conducted on four plots. Measurements during and after the simulations included runoff, rainfall, suspended-sediment concentrations, surface ash layer thickness, soil moisture, soil grain size, soil lost on ignition, and plot topography. Runoff discharge reached a steady state within 7 to 26 minutes. Steady infiltration rates with the 50-mm/h application rainfall intensity approached 20?35 mm/h. If these rates are projected to rainfall application intensities used in many studies of burned area runoff production (about 80 mm/h), the steady discharge rates are on the lower end of measurements from other studies. Experiments using multiple rainfall intensities (three) suggest that runoff begins at rainfall intensities around 20 mm/h at the 1-square-meter scale, an observation consistent with a 10-mm/h rainfall intensity threshold needed for runoff initiation that has been reported in the literature.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Loisel, G., E-mail: gploise@sandia.gov; Lake, P.; Gard, P.
2016-11-15
At Sandia National Laboratories, the x-ray generator Manson source model 5 was upgraded from 10 to 25 kV. The purpose of the upgrade is to drive higher characteristics photon energies with higher throughput. In this work we present characterization studies for the source size and the x-ray intensity when varying the source voltage for a series of K-, L-, and M-shell lines emitted from Al, Y, and Au elements composing the anode. We used a 2-pinhole camera to measure the source size and an energy dispersive detector to monitor the spectral content and intensity of the x-ray source. As themore » voltage increases, the source size is significantly reduced and line intensity is increased for the three materials. We can take advantage of the smaller source size and higher source throughput to effectively calibrate the suite of Z Pulsed Power Facility crystal spectrometers.« less
Wu, Zhiwei; He, Hong S; Liu, Zhihua; Liang, Yu
2013-06-01
Fuel load is often used to prioritize stands for fuel reduction treatments. However, wildfire size and intensity are not only related to fuel loads but also to a wide range of other spatially related factors such as topography, weather and human activity. In prioritizing fuel reduction treatments, we propose using burn probability to account for the effects of spatially related factors that can affect wildfire size and intensity. Our burn probability incorporated fuel load, ignition probability, and spread probability (spatial controls to wildfire) at a particular location across a landscape. Our goal was to assess differences in reducing wildfire size and intensity using fuel-load and burn-probability based treatment prioritization approaches. Our study was conducted in a boreal forest in northeastern China. We derived a fuel load map from a stand map and a burn probability map based on historical fire records and potential wildfire spread pattern. The burn probability map was validated using historical records of burned patches. We then simulated 100 ignitions and six fuel reduction treatments to compare fire size and intensity under two approaches of fuel treatment prioritization. We calibrated and validated simulated wildfires against historical wildfire data. Our results showed that fuel reduction treatments based on burn probability were more effective at reducing simulated wildfire size, mean and maximum rate of spread, and mean fire intensity, but less effective at reducing maximum fire intensity across the burned landscape than treatments based on fuel load. Thus, contributions from both fuels and spatially related factors should be considered for each fuel reduction treatment. Published by Elsevier B.V.
Schuchmann, Maike; Siemers, Björn M
2010-09-17
Only recently data on bat echolocation call intensities is starting to accumulate. Yet, intensity is an ecologically crucial parameter, as it determines the extent of the bats' perceptual space and, specifically, prey detection distance. Interspecifically, we thus asked whether sympatric, congeneric bat species differ in call intensities and whether differences play a role for niche differentiation. Specifically, we investigated whether R. mehelyi that calls at a frequency clearly above what is predicted by allometry, compensates for frequency-dependent loss in detection distance by using elevated call intensity. Maximum echolocation call intensities might depend on body size or condition and thus be used as an honest signal of quality for intraspecific communication. We for the first time investigated whether a size-intensity relation is present in echolocating bats. We measured maximum call intensities and frequencies for all five European horseshoe bat species. Maximum intensity differed among species largely due to R. euryale. Furthermore, we found no compensation for frequency-dependent loss in detection distance in R. mehelyi. Intraspecifically, there is a negative correlation between forearm lengths and intensity in R. euryale and a trend for a negative correlation between body condition index and intensity in R. ferrumequinum. In R. hipposideros, females had 8 dB higher intensities than males. There were no correlations with body size or sex differences and intensity for the other species. Based on call intensity and frequency measurements, we estimated echolocation ranges for our study community. These suggest that intensity differences result in different prey detection distances and thus likely play some role for resource access. It is interesting and at first glance counter-intuitive that, where a correlation was found, smaller bats called louder than large individuals. Such negative relationship between size or condition and vocal amplitude may indicate an as yet unknown physiological or sexual selection pressure.
Schuchmann, Maike; Siemers, Björn M.
2010-01-01
Background Only recently data on bat echolocation call intensities is starting to accumulate. Yet, intensity is an ecologically crucial parameter, as it determines the extent of the bats' perceptual space and, specifically, prey detection distance. Interspecifically, we thus asked whether sympatric, congeneric bat species differ in call intensities and whether differences play a role for niche differentiation. Specifically, we investigated whether R. mehelyi that calls at a frequency clearly above what is predicted by allometry, compensates for frequency-dependent loss in detection distance by using elevated call intensity. Maximum echolocation call intensities might depend on body size or condition and thus be used as an honest signal of quality for intraspecific communication. We for the first time investigated whether a size-intensity relation is present in echolocating bats. Methodology/Principal Findings We measured maximum call intensities and frequencies for all five European horseshoe bat species. Maximum intensity differed among species largely due to R. euryale. Furthermore, we found no compensation for frequency-dependent loss in detection distance in R. mehelyi. Intraspecifically, there is a negative correlation between forearm lengths and intensity in R. euryale and a trend for a negative correlation between body condition index and intensity in R. ferrumequinum. In R. hipposideros, females had 8 dB higher intensities than males. There were no correlations with body size or sex differences and intensity for the other species. Conclusions/Significance Based on call intensity and frequency measurements, we estimated echolocation ranges for our study community. These suggest that intensity differences result in different prey detection distances and thus likely play some role for resource access. It is interesting and at first glance counter-intuitive that, where a correlation was found, smaller bats called louder than large individuals. Such negative relationship between size or condition and vocal amplitude may indicate an as yet unknown physiological or sexual selection pressure. PMID:20862252
NASA Astrophysics Data System (ADS)
Desai, Shraddha S.; Devan, Shylaja; Das, Amrita; Patkar, S. M.; Rao, Mala N.
2018-04-01
Neutron scattering instruments at Dhruva reactor are equipped with in house developed neutron beam flux monitors. Measurements of variations in intensity are essential to normalize the scattered neutron spectra against the reactor power fluctuations, energy of monochromatic beam, and various other factors. Two different beam monitor geometries are considered as per the beam size and optics. These detectors are fabricated with tailor-made designs to suit individual beam size and neutron flux. Pencil size beam monitors for integral intensity measurement are fabricated with coaxial geometry and BF3 fill gas for high n-gamma discrimination and count rate capability. Brass cathode design is modified to SS based rugged design, considering beam transmission. Coaxial beam monitor partially intercepts the collimated beam and gives relative magnitude of the flux with time. For certain experiments, size of beam varies due to use of focusing monochromator. Thus a beam monitor with square sensitive region covering entire beam is essential. Multiwire based planar detector for use in transmission mode is designed. Negligible absorption of neutron beam intensity within the detector hardware is ensured. Design of detectors is tailor made for beam geometry. Both these types of beam monitors are fabricated and characterized at G2 beam line and Triple Axis Spectrometer at Dhruva reactor. Performance of detector is suitable for the beam monitoring up to neutron flux ˜ 106 n/cm2/sec. Design aspects and performance details of these beam monitors are mentioned in the paper.
Duy, Pham K; Chun, Seulah; Chung, Hoeil
2017-11-21
We have systematically characterized Raman scatterings in solid samples with different particle sizes and investigated subsequent trends of particle size-induced intensity variations. For this purpose, both lactose powders and pellets composed of five different particle sizes were prepared. Uniquely in this study, three spectral acquisition schemes with different sizes of laser illuminations and detection windows were employed for the evaluation, since it was expected that the experimental configuration would be another factor potentially influencing the intensity of the lactose peak, along with the particle size itself. In both samples, the distribution of Raman photons became broader with the increase in particle size, as the mean free path of laser photons, the average photon travel distance between consecutive scattering locations, became longer under this situation. When the particle size was the same, the Raman photon distribution was narrower in the pellets since the individual particles were more densely packed in a given volume (the shorter mean free path). When the size of the detection window was small, the number of photons reaching the detector decreased as the photon distribution was larger. Meanwhile, a large-window detector was able to collect the widely distributed Raman photons more effectively; therefore, the trends of intensity change with the variation in particle size were dissimilar depending on the employed spectral acquisition schemes. Overall, the Monte Carlo simulation was effective at probing the photon distribution inside the samples and helped to support the experimental observations.
Evidence of size-selective evolution in the fighting conch from prehistoric subsistence harvesting.
O'Dea, Aaron; Shaffer, Marian Lynne; Doughty, Douglas R; Wake, Thomas A; Rodriguez, Felix A
2014-05-07
Intensive size-selective harvesting can drive evolution of sexual maturity at smaller body size. Conversely, prehistoric, low-intensity subsistence harvesting is not considered an effective agent of size-selective evolution. Uniting archaeological, palaeontological and contemporary material, we show that size at sexual maturity in the edible conch Strombus pugilis declined significantly from pre-human (approx. 7 ka) to prehistoric times (approx. 1 ka) and again to the present day. Size at maturity also fell from early- to late-prehistoric periods, synchronous with an increase in harvesting intensity as other resources became depleted. A consequence of declining size at maturity is that early prehistoric harvesters would have received two-thirds more meat per conch than contemporary harvesters. After exploring the potential effects of selection biases, demographic shifts, environmental change and habitat alteration, these observations collectively implicate prehistoric subsistence harvesting as an agent of size-selective evolution with long-term detrimental consequences. We observe that contemporary populations that are protected from harvesting are slightly larger at maturity, suggesting that halting or even reversing thousands of years of size-selective evolution may be possible.
Evidence of size-selective evolution in the fighting conch from prehistoric subsistence harvesting
O'Dea, Aaron; Shaffer, Marian Lynne; Doughty, Douglas R.; Wake, Thomas A.; Rodriguez, Felix A.
2014-01-01
Intensive size-selective harvesting can drive evolution of sexual maturity at smaller body size. Conversely, prehistoric, low-intensity subsistence harvesting is not considered an effective agent of size-selective evolution. Uniting archaeological, palaeontological and contemporary material, we show that size at sexual maturity in the edible conch Strombus pugilis declined significantly from pre-human (approx. 7 ka) to prehistoric times (approx. 1 ka) and again to the present day. Size at maturity also fell from early- to late-prehistoric periods, synchronous with an increase in harvesting intensity as other resources became depleted. A consequence of declining size at maturity is that early prehistoric harvesters would have received two-thirds more meat per conch than contemporary harvesters. After exploring the potential effects of selection biases, demographic shifts, environmental change and habitat alteration, these observations collectively implicate prehistoric subsistence harvesting as an agent of size-selective evolution with long-term detrimental consequences. We observe that contemporary populations that are protected from harvesting are slightly larger at maturity, suggesting that halting or even reversing thousands of years of size-selective evolution may be possible. PMID:24648229
Calculation of Stress Intensity Factors for Interfacial Cracks in Fiber Metal Laminates
NASA Technical Reports Server (NTRS)
Wang, John T.
2009-01-01
Stress intensity factors for interfacial cracks in Fiber Metal Laminates (FML) are computed by using the displacement ratio method recently developed by Sun and Qian (1997, Int. J. Solids. Struct. 34, 2595-2609). Various FML configurations with single and multiple delaminations subjected to different loading conditions are investigated. The displacement ratio method requires the total energy release rate, bimaterial parameters, and relative crack surface displacements as input. Details of generating the energy release rates, defining bimaterial parameters with anisotropic elasticity, and selecting proper crack surface locations for obtaining relative crack surface displacements are discussed in the paper. Even though the individual energy release rates are nonconvergent, mesh-size-independent stress intensity factors can be obtained. This study also finds that the selection of reference length can affect the magnitudes and the mode mixity angles of the stress intensity factors; thus, it is important to report the reference length used with the calculated stress intensity factors.
Quantifying extreme precipitation events and their hydrologic response in Southeastern Arizona
USDA-ARS?s Scientific Manuscript database
Design criteria such as rainfall intensities and runoff rates for small watersheds (<200km2) are needed for modeling, sizing and design of drainage and flood control structures. In the Southwest US the need for accurate information about these rates is increasingly important as development of range...
Ultrasound with low intensity assisted the synthesis of nanocrystalline TiO2 without calcination.
Ghows, Narjes; Entezari, Mohamad H
2010-06-01
A novel method has been developed for the preparation of nano-sized TiO(2) with anatase phase. Nanoparticles with diameter about 6 nm were prepared at a relatively low temperature (75 degrees C) and short time. The synthesis was carried out by the hydrolysis of titanium tetra-isopropoxide (TTIP) in the presence of water, ethanol, and dispersant under ultrasonic irradiation (500 kHz) at low intensity. The results show that variables such as water/ethanol ratio, irradiation time, and temperature have a great influence on the particle size and crystalline phases of TiO(2) nanoparticles. Characterization of the product was carried out by different techniques such as powder X-ray diffraction (XRD), transmission electron microscopy (TEM), high resolution transmission electron microscopy (HRTEM) and UV-vis spectroscopy. (c) 2010 Elsevier B.V. All rights reserved.
NASA Astrophysics Data System (ADS)
Kuo, Chun-Fu; Chu, Shu-Chun
2013-03-01
Optical vortices possess several special properties, including carrying optical angular momentum (OAM) and exhibiting zero intensity. Vortex array laser beams have attracts many interests due to its special mesh field distributions, which show great potential in the application of multiple optical traps and dark optical traps. Previously study developed an Ince-Gaussian Mode (IGM)-based vortex array laser beam1. This study develops a simulation model based on the discrete dipole approximation (DDA) method for calculating the resultant force acting on a micro-sized spherical dielectric particle that situated at the beam waist of the IGM-based vortex array laser beams1.
The Effect of the Laboratory Specimen on Fatigue Crack Growth Rate
NASA Technical Reports Server (NTRS)
Forth, S. C.; Johnston, W. M.; Seshadri, B. R.
2006-01-01
Over the past thirty years, laboratory experiments have been devised to develop fatigue crack growth rate data that is representative of the material response. The crack growth rate data generated in the laboratory is then used to predict the safe operating envelope of a structure. The ability to interrelate laboratory data and structural response is called similitude. In essence, a nondimensional term, called the stress intensity factor, was developed that includes the applied stresses, crack size and geometric configuration. The stress intensity factor is then directly related to the rate at which cracks propagate in a material, resulting in the material property of fatigue crack growth response. Standardized specimen configurations and experimental procedures have been developed for laboratory testing to generate crack growth rate data that supports similitude of the stress intensity factor solution. In this paper, the authors present laboratory fatigue crack growth rate test data and finite element analyses that show similitude between standard specimen configurations tested using the constant stress ratio test method is unobtainable.
Causes of intraspecific variation in body size among trematode metacercariae.
Saldanha, I; Leung, T L F; Poulin, R
2009-09-01
Inequalities in body size among adult helminths can result in inequalities in reproductive output, with consequences for population dynamics and genetics. These inequalities can result from growth differences among larval worms inside intermediate hosts that persist into the adult stage. Here, we investigate the effects of both host body size and intensity of infection on the sizes of metacercariae of the trematode Maritrema novaezealandensis (Microphallidae) inside their second intermediate host, the isopod Paridotea ungulata (Idoteidae). Among the more than 1500 metacercariae recovered and individually measured, there was no relationship between the mean diameter of metacercarial cysts per isopod and isopod body length. However, intensity of infection correlated negatively with the mean diameter of cysts within an isopod, i.e. metacercariae in crowded infections attained smaller sizes on average. In contrast, the variability in cyst sizes per isopod, measured as the coefficient of variation, was independent of both isopod body length and infection intensity. Our results show that a disproportionate number of relatively small metacercariae come from the relatively few hosts in which a large fraction of all metacercariae are aggregated. The combination of aggregation and intensity-dependent growth generates inequalities in sizes among metacercariae that will be passed on to adult worm populations in definitive hosts.
NASA Astrophysics Data System (ADS)
Yuksel, Heba; Davis, Christopher C.
2006-09-01
Intensity fluctuations at the receiver in free space optical (FSO) communication links lead to a received power variance that depends on the size of the receiver aperture. Increasing the size of the receiver aperture reduces the power variance. This effect of the receiver size on power variance is called aperture averaging. If there were no aperture size limitation at the receiver, then there would be no turbulence-induced scintillation. In practice, there is always a tradeoff between aperture size, transceiver weight, and potential transceiver agility for pointing, acquisition and tracking (PAT) of FSO communication links. We have developed a geometrical simulation model to predict the aperture averaging factor. This model is used to simulate the aperture averaging effect at given range by using a large number of rays, Gaussian as well as uniformly distributed, propagating through simulated turbulence into a circular receiver of varying aperture size. Turbulence is simulated by filling the propagation path with spherical bubbles of varying sizes and refractive index discontinuities statistically distributed according to various models. For each statistical representation of the atmosphere, the three-dimensional trajectory of each ray is analyzed using geometrical optics. These Monte Carlo techniques have proved capable of assessing the aperture averaging effect, in particular, the quantitative expected reduction in intensity fluctuations with increasing aperture diameter. In addition, beam wander results have demonstrated the range-cubed dependence of mean-squared beam wander. An effective turbulence parameter can also be determined by correlating beam wander behavior with the path length.
NASA Astrophysics Data System (ADS)
Yoon, Jinsik; Kim, Kibeom; Park, Wook
2017-07-01
We present an essential method for generating microparticles uniformly in a single ultraviolet (UV) light exposure area for optofluidic maskless lithography. In the optofluidic maskless lithography process, the productivity of monodisperse microparticles depends on the size of the UV exposure area. An effective fabrication area is determined by the size of the UV intensity profile map, satisfying the required uniformity of UV intensity. To increase the productivity of monodisperse microparticles in optofluidic maskless lithography, we expanded the effective UV exposure area by modulating the intensity of the desired UV light pattern based on the premeasured UV intensity profile map. We verified the improvement of the uniformity of the microparticles generated by the proposed modulation technique, providing histogram analyses of the conjugated fluorescent intensities and the sizes of the microparticles. Additionally, we demonstrated the generation of DNA uniformly encapsulated in microparticles.
Light scattering properties of spheroidal particles
NASA Technical Reports Server (NTRS)
Asano, S.
1979-01-01
In the present paper, the light scattering characteristics of spheroidal particles are evaluated within the framework of a scattering theory developed for a homogeneous isotropic spheroid. This approach is shown to be well suited for computing the scattering quantities of spheroidal particles of fairly large sizes (up to a size parameter of 30). The effects of particle size, shape, index of refraction, and orientation on the scattering efficiency factors and the scattering intensity functions are studied and interpreted physically. It is shown that, in the case of oblique incidence, the scattering properties of a long slender prolate spheroid resemble those of an infinitely long circular cylinder.
Effect of gold nanoparticle size on acoustic cavitation using chemical dosimetry method.
Shanei, Ahmad; Shanei, Mohammad Mahdi
2017-01-01
When a liquid is irradiated with high intensities of ultrasound irradiation, acoustic cavitation occurs. Acoustic cavitation generates free radicals from the breakdown of water and other molecules. Cavitation can be fatal to cells and is utilized to destroy cancer tumors. The existence of particles in liquid provides nucleation sites for cavitation bubbles and leads to decrease the ultrasonic intensity threshold needed for cavitation onset. In the present investigation, the effect of gold nanoparticles with appropriate amount and size on the acoustic cavitation activity has been shown by determining hydroxyl radicals in terephthalic acid solutions containing 15, 20, 28 and 35nm gold nanoparticles sizes by using 1MHz low level ultrasound. The effect of sonication intensity in hydroxyl radical production was considered. The recorded fluorescence signal in terephthalic acid solutions containing gold nanoparticles was considerably higher than the terephthalic acid solutions without gold nanoparticles at different intensities of ultrasound irradiation. Also, the results showed that the recorded fluorescence signal intensity in terephthalic acid solution containing finer size of gold nanoparticles was lower than the terephthalic acid solutions containing larger size of gold nanoparticles. Acoustic cavitation in the presence of gold nanoparticles can be used as a way for improving therapeutic effects on the tumors. Copyright © 2016 Elsevier B.V. All rights reserved.
Kato, Haruhisa; Nakamura, Ayako; Takahashi, Kayori; Kinugasa, Shinichi
2012-01-01
Accurate determination of the intensity-average diameter of polystyrene latex (PS-latex) by dynamic light scattering (DLS) was carried out through extrapolation of both the concentration of PS-latex and the observed scattering angle. Intensity-average diameter and size distribution were reliably determined by asymmetric flow field flow fractionation (AFFFF) using multi-angle light scattering (MALS) with consideration of band broadening in AFFFF separation. The intensity-average diameter determined by DLS and AFFFF-MALS agreed well within the estimated uncertainties, although the size distribution of PS-latex determined by DLS was less reliable in comparison with that determined by AFFFF-MALS. PMID:28348293
High temperatures disrupt Artemia franciscana mating patterns and impact sexual selection intensity
NASA Astrophysics Data System (ADS)
Santos, Maria R.; Vieira, Natividade; Monteiro, Nuno M.
2018-07-01
Temperature plays a critical role in survival and reproduction, especially in ectotherms. Therefore, it is important to understand the mechanisms influencing life history traits and reproductive behaviours in order to predict climate change impacts on species' occurrence and performance. Here, we used the crustacean Artemia franciscana to investigate the potential impacts of temperature on life history traits, mating patterns and intensity of sexual selection. We reared A. franciscana at three temperatures 20 °C, 25 °C, and 30 °C and measured life history traits such as growth, mortality or development of sexual traits. Our observations confirmed a clear link between life history traits and temperature, with advanced sexual maturity and increased mortality rates following temperature rises. Also, we found that mating is size assortative close to the ideal developmental temperature. Nevertheless, when temperatures deviate from the optimum, mating patterns were altered. Although selection intensity for females remained similar at all tested temperatures, as males preferentially mated with the larger females, size assortative mating disappeared at the highest temperature. Overall, our results highlight the potential for a temperature-dependent disruption of A. franciscana mating patterns. This disruption is especially pronounced under high temperatures as reproduction becomes progressively more random, thus entailing a relaxation of sexual selection intensity.
Herbrecht, Evelyn; Kievit, Esther; Spiegel, René; Dima, Diana; Goth, Kirstin; Schmeck, Klaus
2015-01-01
In autism spectrum disorders (ASDs), impairments in fundamental social abilities and a lack of interest in social stimuli become apparent early in life. These impairments are thought to negatively affect further brain and behavioural development. Early intensive interventions can help to attenuate social-development and other risk factors and, thus, to ameliorate the deficits associated with ASDs. We present FIAS, an intensive early intervention approach for young children with ASD, which aims at developing children's social motivation. During 18 days, therapists work continuously for 6 h a day with the affected child, involving the whole family in a day care setting. Follow-up care at home over 1 year as well as fresh-up interventions and inclusion in kindergarten or a play group should stabilise the effects and help to respond to further challenges. Here, we present observations from the first 12 patients (25-48 months of age) treated according to the FIAS approach. We evaluated changes in core autistic symptoms and level of functioning after the 18 days of intensive intervention. Beyond standardised assessment, two innovative video-based instruments (Autism Behaviour Coding System and Evaluationsfragebogen) have been developed to assess autistic symptoms and interaction parameters during intervention. Improvements were noted in most core autistic symptom domains, with the highest effect sizes in domains like eye contact, communication, repetitive behaviour, imitation, motivation and reciprocity. In addition, the level of functioning significantly improved. The first evaluation of the FIAS approach shows promising results, as the FIAS intervention appears to improve core autistic symptom domains as well as the level of everyday functioning. Limitations of this study are the small sample size and the lack of a control group. A more comprehensive and longitudinal evaluation is in progress; this will focus on the stability of the observed effects and will attempt to identify potential predictors of treatment response. © 2015 S. Karger AG, Basel.
NASA Astrophysics Data System (ADS)
Mehrübeoğlu, Mehrübe; McLauchlan, Lifford
2006-02-01
The goal of this project was to detect the intensity of traffic on a road at different times of the day during daytime. Although the work presented utilized images from a section of a highway, the results of this project are intended for making decisions on the type of intervention necessary on any given road at different times for traffic control, such as installation of traffic signals, duration of red, green and yellow lights at intersections, and assignment of traffic control officers near school zones or other relevant locations. In this project, directional patterns are used to detect and count the number of cars in traffic images over a fixed area of the road to determine local traffic intensity. Directional patterns are chosen because they are simple and common to almost all moving vehicles. Perspective vision effects specific to each camera orientation has to be considered, as they affect the size and direction of patterns to be recognized. In this work, a simple and fast algorithm has been developed based on horizontal directional pattern matching and perspective vision adjustment. The results of the algorithm under various conditions are presented and compared in this paper. Using the developed algorithm, the traffic intensity can accurately be determined on clear days with average sized cars. The accuracy is reduced on rainy days when the camera lens contains raindrops, when there are very long vehicles, such as trucks or tankers, in the view, and when there is very low light around dusk or dawn.
The application of computational chemistry to lignin
Thomas Elder; Laura Berstis; Nele Sophie Zwirchmayr; Gregg T. Beckham; Michael F. Crowley
2017-01-01
Computational chemical methods have become an important technique in the examination of the structure and reactivity of lignin. The calculations can be based either on classical or quantum mechanics, with concomitant differences in computational intensity and size restrictions. The current paper will concentrate on results developed from the latter type of calculations...
An aerial survey method to estimate sea otter abundance
Bodkin, James L.; Udevitz, Mark S.; Garner, Gerald W.; Amstrup, Steven C.; Laake, Jeffrey L.; Manly, Bryan F.J.; McDonald, Lyman L.; Robertson, Donna G.
1999-01-01
Sea otters (Enhydra lutris) occur in shallow coastal habitats and can be highly visible on the sea surface. They generally rest in groups and their detection depends on factors that include sea conditions, viewing platform, observer technique and skill, distance, habitat and group size. While visible on the surface, they are difficult to see while diving and may dive in response to an approaching survey platform. We developed and tested an aerial survey method that uses intensive searches within portions of strip transects to adjust for availability and sightability biases. Correction factors are estimated independently for each survey and observer. In tests of our method using shore-based observers, we estimated detection probabilities of 0.52-0.72 in standard strip-transects and 0.96 in intensive searches. We used the survey method in Prince William Sound, Alaska to estimate a sea otter population size of 9,092 (SE = 1422). The new method represents an improvement over various aspects of previous methods, but additional development and testing will be required prior to its broad application.
Association of unit size, resource utilization and occupancy with outcomes of preterm infants.
Shah, P S; Mirea, L; Ng, E; Solimano, A; Lee, S K
2015-07-01
Assess association of NICU size, and occupancy rate and resource utilization at admission with neonatal outcome. Retrospective cohort study of 9978 infants born at 23-32 weeks gestation and admitted to 23 tertiary-level Canadian NICUs during 2010-2012. Adjusted odds ratios (AOR) were estimated for a composite outcome of mortality/any major morbidity with respect to NICU size, occupancy rate and intensity of resource utilization at admission. A total of 2889 (29%) infants developed the composite outcome, the odds of which were higher for 16-29, 30-36 and >36-bed NICUs compared with <16-bed NICUs (AOR (95% CI): 1.47 (1.25-1.73); 1.49 (1.25-1.78); 1.55 (1.29-1.87), respectively) and for NICUs with higher resource utilization at admission (AOR: 1.30 (1.08-1.56), Q4 vs Q1) but not different according to NICU occupancy. Larger NICUs and more intense resource utilization at admission are associated with higher odds of a composite adverse outcome in very preterm infants.
Raindrop Characteristics in the Pacific Northwest
USDA-ARS?s Scientific Manuscript database
The U.S. Pacific Northwest, influenced by maritime air masses for most of the year, generally exhibits low rainfall intensities. The drop-size characteristics of such low-intensity storms are rarely studied. An investigation of natural drop sizes and their distribution was conducted at the Palouse ...
Microfluidic sorting of protein nanocrystals by size for X-ray free-electron laser diffraction
Abdallah, Bahige G.; Zatsepin, Nadia A.; Roy-Chowdhury, Shatabdi; Coe, Jesse; Conrad, Chelsie E.; Dörner, Katerina; Sierra, Raymond G.; Stevenson, Hilary P.; Camacho-Alanis, Fernanda; Grant, Thomas D.; Nelson, Garrett; James, Daniel; Calero, Guillermo; Wachter, Rebekka M.; Spence, John C. H.; Weierstall, Uwe; Fromme, Petra; Ros, Alexandra
2015-01-01
The advent and application of the X-ray free-electron laser (XFEL) has uncovered the structures of proteins that could not previously be solved using traditional crystallography. While this new technology is powerful, optimization of the process is still needed to improve data quality and analysis efficiency. One area is sample heterogeneity, where variations in crystal size (among other factors) lead to the requirement of large data sets (and thus 10–100 mg of protein) for determining accurate structure factors. To decrease sample dispersity, we developed a high-throughput microfluidic sorter operating on the principle of dielectrophoresis, whereby polydisperse particles can be transported into various fluid streams for size fractionation. Using this microsorter, we isolated several milliliters of photosystem I nanocrystal fractions ranging from 200 to 600 nm in size as characterized by dynamic light scattering, nanoparticle tracking, and electron microscopy. Sorted nanocrystals were delivered in a liquid jet via the gas dynamic virtual nozzle into the path of the XFEL at the Linac Coherent Light Source. We obtained diffraction to ∼4 Å resolution, indicating that the small crystals were not damaged by the sorting process. We also observed the shape transforms of photosystem I nanocrystals, demonstrating that our device can optimize data collection for the shape transform-based phasing method. Using simulations, we show that narrow crystal size distributions can significantly improve merged data quality in serial crystallography. From this proof-of-concept work, we expect that the automated size-sorting of protein crystals will become an important step for sample production by reducing the amount of protein needed for a high quality final structure and the development of novel phasing methods that exploit inter-Bragg reflection intensities or use variations in beam intensity for radiation damage-induced phasing. This method will also permit an analysis of the dependence of crystal quality on crystal size. PMID:26798818
Microfluidic sorting of protein nanocrystals by size for X-ray free-electron laser diffraction
Abdallah, Bahige G.; Zatsepin, Nadia A.; Roy-Chowdhury, Shatabdi; ...
2015-08-19
We report that the advent and application of the X-ray free-electron laser (XFEL) has uncovered the structures of proteins that could not previously be solved using traditional crystallography. While this new technology is powerful, optimization of the process is still needed to improve data quality and analysis efficiency. One area is sample heterogeneity, where variations in crystal size (among other factors) lead to the requirement of large data sets (and thus 10–100 mg of protein) for determining accurate structure factors. To decrease sample dispersity, we developed a high-throughput microfluidic sorter operating on the principle of dielectrophoresis, whereby polydisperse particles canmore » be transported into various fluid streams for size fractionation. Using this microsorter, we isolated several milliliters of photosystem I nanocrystal fractions ranging from 200 to 600 nm in size as characterized by dynamic light scattering, nanoparticle tracking, and electron microscopy. Sorted nanocrystals were delivered in a liquid jet via the gas dynamic virtual nozzle into the path of the XFEL at the Linac Coherent Light Source. We obtained diffraction to ~4 Å resolution, indicating that the small crystals were not damaged by the sorting process. We also observed the shape transforms of photosystem I nanocrystals, demonstrating that our device can optimize data collection for the shape transform-based phasing method. Using simulations, we show that narrow crystal size distributions can significantly improve merged data quality in serial crystallography. From this proof-of-concept work, we expect that the automated size-sorting of protein crystals will become an important step for sample production by reducing the amount of protein needed for a high quality final structure and the development of novel phasing methods that exploit inter-Bragg reflection intensities or use variations in beam intensity for radiation damage-induced phasing. Ultimately, this method will also permit an analysis of the dependence of crystal quality on crystal size.« less
NASA Technical Reports Server (NTRS)
Pitts, D. E.; Badhwar, G.
1980-01-01
The development of agricultural remote sensing systems requires knowledge of agricultural field size distributions so that the sensors, sampling frames, image interpretation schemes, registration systems, and classification systems can be properly designed. Malila et al. (1976) studied the field size distribution for wheat and all other crops in two Kansas LACIE (Large Area Crop Inventory Experiment) intensive test sites using ground observations of the crops and measurements of their field areas based on current year rectified aerial photomaps. The field area and size distributions reported in the present investigation are derived from a representative subset of a stratified random sample of LACIE sample segments. In contrast to previous work, the obtained results indicate that most field-size distributions are not log-normally distributed. The most common field size observed in this study was 10 acres for most crops studied.
Sensitivity of the simulation of tropical cyclone size to microphysics schemes
NASA Astrophysics Data System (ADS)
Chan, Kelvin T. F.; Chan, Johnny C. L.
2016-09-01
The sensitivity of the simulation of tropical cyclone (TC) size to microphysics schemes is studied using the Advanced Hurricane Weather Research and Forecasting Model (WRF). Six TCs during the 2013 western North Pacific typhoon season and three mainstream microphysics schemes-Ferrier (FER), WRF Single-Moment 5-class (WSM5) and WRF Single-Moment 6-class (WSM6)-are investigated. The results consistently show that the simulated TC track is not sensitive to the choice of microphysics scheme in the early simulation, especially in the open ocean. However, the sensitivity is much greater for TC intensity and inner-core size. The TC intensity and size simulated using the WSM5 and WSM6 schemes are respectively higher and larger than those using the FER scheme in general, which likely results from more diabatic heating being generated outside the eyewall in rainbands. More diabatic heating in rainbands gives higher inflow in the lower troposphere and higher outflow in the upper troposphere, with higher upward motion outside the eyewall. The lower-tropospheric inflow would transport absolute angular momentum inward to spin up tangential wind predominantly near the eyewall, leading to the increment in TC intensity and size (the inner-core size, especially). In addition, the inclusion of graupel microphysics processes (as in WSM6) may not have a significant impact on the simulation of TC track, intensity and size.
Cheng, Xinfeng; Zhang, Min; Xu, Baoguo; Adhikari, Benu; Sun, Jincai
2015-11-01
Ultrasonic processing is a novel and promising technology in food industry. The propagation of ultrasound in a medium generates various physical and chemical effects and these effects have been harnessed to improve the efficiency of various food processing operations. Ultrasound has also been used in food quality control as diagnostic technology. This article provides an overview of recent developments related to the application of ultrasound in low temperature and closely related processes such as freezing, thawing, freeze concentration and freeze drying. The applications of high intensity ultrasound to improve the efficiency of freezing process, to control the size and size distribution of ice crystals and to improve the quality of frozen foods have been discussed in considerable detail. The use of low intensity ultrasound in monitoring the ice content and to monitor the progress of freezing process has also been highlighted. Copyright © 2015 Elsevier B.V. All rights reserved.
Taisova, A S; Yakovlev, A G; Fetisova, Z G
2014-03-01
This work continuous a series of studies devoted to discovering principles of organization of natural antennas in photosynthetic microorganisms that generate in vivo large and highly effective light-harvesting structures. The largest antenna is observed in green photosynthesizing bacteria, which are able to grow over a wide range of light intensities and adapt to low intensities by increasing of size of peripheral BChl c/d/e antenna. However, increasing antenna size must inevitably cause structural changes needed to maintain high efficiency of its functioning. Our model calculations have demonstrated that aggregation of the light-harvesting antenna pigments represents one of the universal structural factors that optimize functioning of any antenna and manage antenna efficiency. If the degree of aggregation of antenna pigments is a variable parameter, then efficiency of the antenna increases with increasing size of a single aggregate of the antenna. This means that change in degree of pigment aggregation controlled by light-harvesting antenna size is biologically expedient. We showed in our previous work on the oligomeric chlorosomal BChl c superantenna of green bacteria of the Chloroflexaceae family that this principle of optimization of variable antenna structure, whose size is controlled by light intensity during growth of bacteria, is actually realized in vivo. Studies of this phenomenon are continued in the present work, expanding the number of studied biological materials and investigating optical linear and nonlinear spectra of chlorosomes having different structures. We show for oligomeric chlorosomal superantennas of green bacteria (from two different families, Chloroflexaceae and Oscillochloridaceae) that a single BChl c aggregate is of small size, and the degree of BChl c aggregation is a variable parameter, which is controlled by the size of the entire BChl c superantenna, and the latter, in turn, is controlled by light intensity in the course of cell culture growth.
Paradiso, Roberta; De Pascale, Stefania
2014-01-01
Mediterranean greenhouses for cultivation of Phalaenopsis orchids reproduce the warm, humid, and shaded environment of tropical underbrush. Heating represents the highest production cost, due to the high thermal requirements and the long unproductive phase of juvenility, in which plants attain the critical size for flowering. Our researches aimed to investigate the effect of plant size, temperature, and light intensity, during the phase of flower induction, on flowering of modern genotypes selected for Mediterranean greenhouses. Three experiments were carried out to compare (i) plant size: reduced size versus size considered optimal for flowering (hybrids "Sogo Yukidian," "Chain Xen Diamond," and "Pinlong"); (ii) temperature: moderate reduction of temperature versus standard thermal regime (hybrid "Premium"); (iii) light intensity: supplemental lighting versus reference light intensity (hybrid "Premium"). The premature exposure of plants to the inductive treatment delayed the beginning of flowering and reduced the flower stem quality, in all the tested hybrids. In "Premium," the lower temperature did not affect flowering earliness and commercial quality of flower stems compared to the standard regime, whereas it promoted stem branching. In the same hybrid, supplemental lighting anticipated flowering and promoted the emission of the second stem and the stem branching, compared to the reference light regime.
Vaugoyeau, Marie; Adriaensen, Frank; Artemyev, Alexandr; Bańbura, Jerzy; Barba, Emilio; Biard, Clotilde; Blondel, Jacques; Bouslama, Zihad; Bouvier, Jean-Charles; Camprodon, Jordi; Cecere, Francesco; Charmantier, Anne; Charter, Motti; Cichoń, Mariusz; Cusimano, Camillo; Czeszczewik, Dorota; Demeyrier, Virginie; Doligez, Blandine; Doutrelant, Claire; Dubiec, Anna; Eens, Marcel; Eeva, Tapio; Faivre, Bruno; Ferns, Peter N; Forsman, Jukka T; García-Del-Rey, Eduardo; Goldshtein, Aya; Goodenough, Anne E; Gosler, Andrew G; Grégoire, Arnaud; Gustafsson, Lars; Harnist, Iga; Hartley, Ian R; Heeb, Philipp; Hinsley, Shelley A; Isenmann, Paul; Jacob, Staffan; Juškaitis, Rimvydas; Korpimäki, Erkki; Krams, Indrikis; Laaksonen, Toni; Lambrechts, Marcel M; Leclercq, Bernard; Lehikoinen, Esa; Loukola, Olli; Lundberg, Arne; Mainwaring, Mark C; Mänd, Raivo; Massa, Bruno; Mazgajski, Tomasz D; Merino, Santiago; Mitrus, Cezary; Mönkkönen, Mikko; Morin, Xavier; Nager, Ruedi G; Nilsson, Jan-Åke; Nilsson, Sven G; Norte, Ana C; Orell, Markku; Perret, Philippe; Perrins, Christopher M; Pimentel, Carla S; Pinxten, Rianne; Richner, Heinz; Robles, Hugo; Rytkönen, Seppo; Senar, Juan Carlos; Seppänen, Janne T; Pascoal da Silva, Luis; Slagsvold, Tore; Solonen, Tapio; Sorace, Alberto; Stenning, Martyn J; Tryjanowski, Piotr; von Numers, Mikael; Walankiewicz, Wieslaw; Møller, Anders Pape
2016-08-01
The increase in size of human populations in urban and agricultural areas has resulted in considerable habitat conversion globally. Such anthropogenic areas have specific environmental characteristics, which influence the physiology, life history, and population dynamics of plants and animals. For example, the date of bud burst is advanced in urban compared to nearby natural areas. In some birds, breeding success is determined by synchrony between timing of breeding and peak food abundance. Pertinently, caterpillars are an important food source for the nestlings of many bird species, and their abundance is influenced by environmental factors such as temperature and date of bud burst. Higher temperatures and advanced date of bud burst in urban areas could advance peak caterpillar abundance and thus affect breeding phenology of birds. In order to test whether laying date advance and clutch sizes decrease with the intensity of urbanization, we analyzed the timing of breeding and clutch size in relation to intensity of urbanization as a measure of human impact in 199 nest box plots across Europe, North Africa, and the Middle East (i.e., the Western Palearctic) for four species of hole-nesters: blue tits (Cyanistes caeruleus), great tits (Parus major), collared flycatchers (Ficedula albicollis), and pied flycatchers (Ficedula hypoleuca). Meanwhile, we estimated the intensity of urbanization as the density of buildings surrounding study plots measured on orthophotographs. For the four study species, the intensity of urbanization was not correlated with laying date. Clutch size in blue and great tits does not seem affected by the intensity of urbanization, while in collared and pied flycatchers it decreased with increasing intensity of urbanization. This is the first large-scale study showing a species-specific major correlation between intensity of urbanization and the ecology of breeding. The underlying mechanisms for the relationships between life history and urbanization remain to be determined. We propose that effects of food abundance or quality, temperature, noise, pollution, or disturbance by humans may on their own or in combination affect laying date and/or clutch size.
NASA Astrophysics Data System (ADS)
Monfared, S. K.; Buttler, W. T.; Frayer, D. K.; Grover, M.; LaLone, B. M.; Stevens, G. D.; Stone, J. B.; Turley, W. D.; Schauer, M. M.
2015-06-01
We report on the development of a diagnostic to provide constraints on the size of particles ejected from shocked metallic surfaces. The diagnostic is based on measurements of the intensity of laser light transmitted through a cloud of ejected particles as well as the angular distribution of scattered light, and the analysis of the resulting data is done using the Mie solution. We describe static experiments to test our experimental apparatus and present initial results of dynamic experiments on Sn targets. Improvements for future experiments are briefly discussed.
Strong-Field Driven Dynamics of Metal and Dielectric Nanoparticles
NASA Astrophysics Data System (ADS)
Powell, Jeffrey
The motion of electrons in atoms, molecules, and solids in the presence of intense electromagnetic radiation is an important research topic in physics and physical chemistry because of its fundamental nature and numerous practical applications, ranging from precise machining of materials to optical control of chemical reactions and light-driven electronic devices. Mechanisms of light-matter interactions critically depend on the dimensions of the irradiated system and evolve significantly from single atoms or molecules to the macroscopic bulk. Nanoparticles provide the link between these two extremes. In this thesis, I take advantage of this bridge to study light-matter interactions as a function of nanoparticle size, shape, and composition. I present here three discrete, but interconnected, experiments contributing to our knowledge of nanoparticle properties and their response to intense, short-pulsed light fields. First, I investigate how individual nanoparticles interact with each other in solution, studying their temperature-dependent solubility. The interaction potential between 5.5nm gold nanoparticles, ligated by an alkanethiol was found to be -0.165eV, in reasonable agreement with a phenomenological model. The other two experiments explore ultrafast dynamics driven by intense femtosecond lasers in isolated, gas-phase metallic and dielectric nanoparticles. Photoelectron momentum imaging is applied to study the response of gold, silica, and gold-shell/silica-core nanoparticles (ranging from single to several hundred nanometers in size) with near-infrared (NIR), 25 fs laser pulses in the intensity range of 1011 - 1014 W/cm2. These measurements, which constitute the bulk of my graduate work, reveal the complex interplay between the external optical field and the induced near-field of the nanoparticle, resulting in the emission of very energetic electrons that are much faster than those emitted from isolated atoms or molecules exposed to the same light pulses. The highest photoelectron energies ("cutoffs") were measured as a function of laser intensity, nanoparticle material and size. We found that the energy cutoffs increase monotonically with laser intensity and nanoparticle size, except for the gold/silica hybrid where the plasmon resonance response modifies this behavior at low intensities. The measured photoelectron spectra for metallic nanoparticles display a large energy enhancement over silica. Finally, the last part of this thesis explores the possibility to apply time-resolved x-ray scattering as a probe of the ultrafast dynamics in isolated nanoparticles driven by very intense ( 1015 W/cm2) NIR laser radiation. To do this, I developed and built a nanoparticle source capable of injecting single, gas-phase nanoparticles with a narrow size distribution into the laser focus. We used femtosecond x-ray pulses from an x-ray free electron laser (XFEL) to map the evolution of the laser-irradiated nanoparticle. The ultrafast dynamics were observed in the single-shot x-ray diffraction patterns measured as a function of delay between the NIR and x-ray pulses, which allows for femtosecond temporal and nanometer spatial resolution. We found that the intense IR laser pulse rapidly ionizes the nanoparticle, effectively turning it into a nanoplasma within less than a picosecond, and observed signatures of the nanoparticle surface softening on a few hundred-femtosecond time scale.
Low pressure laser ablation coupled to inductively coupled plasma mass spectrometry
NASA Astrophysics Data System (ADS)
Fliegel, Daniel; Günther, Detlef
2006-07-01
The particle size distribution in laser ablation inductively coupled plasma mass spectrometry is known to be a critical parameter for complete vaporization of particles. Any strategy to reduce the particle size distribution of laser generated aerosols has the potential to increase the ion signal intensity and to reduce fractionation effects. Due to the fact that vapor generation, nucleation, condensation, and agglomeration take place within an extremely short period of time, ablation under atmospheric pressure might not allow influencing these processes while under reduced pressure condition the cooling of the aerosol and therefore the condensation is expected to be slower. In this study, a low pressure laser ablation cell for the generation of laser aerosols was coupled to an ICP-MS. In contrast to the previously developed trapped ablation mode, the newly designed cell allows the adjustment of the pressure in the ablation cell between 20 and 1400 mbar prior to the ablation. Ablation experiments carried out using this configuration showed a dependence of the aerosol properties (size distribution and particle structure) on the ablation cell pressure. The intensity ratio U/Th measured as a figure of merit for complete vaporization within the ICP indicated a change in the aerosol structure at approximately 500 mbar toward smaller particle size. A significant difference between low pressure and at ambient pressure ablated aerosol was observed. The intensity ratios (U/Th) of the ablated sample moves closer to the bulk composition at lower pressures at the expense of sensitivity. Therefore the decrease in the ICP-MS signal intensity in the low pressure cell can be attributed to vapor deposition within the ablation cell walls. Moreover, scanning electron microscope images of aerosols collected on filters after the low pressure ablation cell suggest the possibility of a slower cooling velocity of the aerosol, which was observed in the condensed material on the surface of ejected spherical particles. The expansion of the laser aerosol was also investigated using polished brass substrates in the expansion path-way for particle collection.
Characterization of x- and gamma- radiation in relativistically intense laser-solid interactions
NASA Astrophysics Data System (ADS)
Hou, Bixue; Zulick, Calvin; Zhao, Zhen; Nees, John; Batson, Thomas; Maksimchuk, Anatoly; Thomas, Alexander G. R.; Krushelnick, Karl; CenterUltrafast Optical Science Team
2013-10-01
Using a high resolution (λ/ Δλ > 100) high purity germanium detector, the angular and material dependence, and the intensity scaling, of bremsstrahlung gamma radiation from relativistically intense (I > 1018 W/cm2) laser-solid interactions have been characterized at energies between 0.1 and 1 MeV with the high-repetition rate (500 Hz) Lambda-Cubed laser facility. The bremsstrahlung spectra of SiO2, Mo, and Eu2O3 were observed to have two-temperature energy distributions, corresponding to two different groups of electrons and depending on both laser intensity and observation angle. The spectra and source sizes of hard x-radiation under 0.1 MeV are also studied. These x-ray sources are being developed for phase-contrast imaging. Support provided by DHS (EECS-0833499), AFOSR (FA99550-12-1-0310), ARO (W911NF-11-1-0116).
Intellectual Capital and Corporate Performance in Knowledge-Intensive SMEs
ERIC Educational Resources Information Center
Cohen, Sandra; Kaimenakis, Nikolaos
2007-01-01
Purpose: In recent years a significant number of intellectual capital (IC) metrics has been developed and applied in many organizations. However, there is still a strong need to specify the relations among the different categories of intellectual assets that exist in the context of small to medium-sized enterprises (SME), and to determine the way…
NASA Astrophysics Data System (ADS)
Lisé-Pronovost, Agathe; St-Onge, Guillaume; Gogorza, Claudia; Haberzettl, Torsten; Jouve, Guillaume; Francus, Pierre; Ohlendorf, Christian; Gebhardt, Catalina; Zolitschka, Bernd
2015-02-01
The sedimentary archive from Laguna Potrok Aike is the only continuous record reaching back to the last Glacial period in continental southeastern Patagonia. Located in the path of the Southern Hemisphere westerly winds and in the source region of dust deposited in Antarctica during Glacial periods, southern Patagonia is a vantage point to reconstruct past changes in aeolian activity. Here we use high-resolution rock-magnetic and physical grain size data from site 2 of the International Continental scientific Drilling Program (ICDP) Potrok Aike maar lake Sediment Archive Drilling prOject (PASADO) in order to develop magnetic proxies of dust and wind intensity at 52°S since 51,200 cal BP. Rock-magnetic analysis indicates the magnetic mineral assemblage is dominated by detrital magnetite. Based on the estimated flux of magnetite to the lake and comparison with distal dust records from the Southern Ocean and Antarctica, kLF is interpreted as a dust indicator in the dust source of southern Patagonia at the millennial time scale, when ferrimagnetic grain size and coercivity influence are minimal. Comparison to physical grain-size data indicates that the median destructive field of isothermal remanent magnetization (MDFIRM) mostly reflects medium to coarse magnetite bearing silts typically transported by winds for short-term suspension. Comparison with wind-intensity proxies from the Southern Hemisphere during the last Glacial period and with regional records from Patagonia since the last deglaciation including marine, lacustrine and peat bog sediments as well as speleothems reveals similar variability with MDFIRM up to the centennial time scale. MDFIRM is interpreted as a wind-intensity proxy independent of moisture changes for southeastern Patagonia, with stronger winds capable of transporting coarser magnetite bearing silts to the lake.
Genome size and metabolic intensity in tetrapods: a tale of two lines
Vinogradov, Alexander E; Anatskaya, Olga V
2005-01-01
We show the negative link between genome size and metabolic intensity in tetrapods, using the heart index (relative heart mass) as a unified indicator of metabolic intensity in poikilothermal and homeothermal animals. We found two separate regression lines of heart index on genome size for reptiles–birds and amphibians–mammals (the slope of regression is steeper in reptiles–birds). We also show a negative correlation between GC content and nucleosome formation potential in vertebrate DNA, and, consistent with this relationship, a positive correlation between genome GC content and nuclear size (independent of genome size). It is known that there are two separate regression lines of genome GC content on genome size for reptiles–birds and amphibians–mammals: reptiles–birds have the relatively higher GC content (for their genome sizes) compared to amphibians–mammals. Our results suggest uniting all these data into one concept. The slope of negative regression between GC content and nucleosome formation potential is steeper in exons than in non-coding DNA (where nucleosome formation potential is generally higher), which indicates a special role of non-coding DNA for orderly chromatin organization. The chromatin condensation and nuclear size are supposed to be key parameters that accommodate the effects of both genome size and GC content and connect them with metabolic intensity. Our data suggest that the reptilian–birds clade evolved special relationships among these parameters, whereas mammals preserved the amphibian-like relationships. Surprisingly, mammals, although acquiring a more complex general organization, seem to retain certain genome-related properties that are similar to amphibians. At the same time, the slope of regression between nucleosome formation potential and GC content is steeper in poikilothermal than in homeothermal genomes, which suggests that mammals and birds acquired certain common features of genomic organization. PMID:16519230
NASA Technical Reports Server (NTRS)
Craven, P. D.; Gary, G. A.
1972-01-01
The Mie theory of light scattering by spheres was used to calculate the scattered intensity functions resulting from single scattering in a polydispersed collection of spheres. The distribution used behaves according to the inverse fourth power law; graphs and tables for the angular dependence of the intensity and polarization for this law are given. The effects of the particle size range and the integration increment are investigated.
Dependence of Hurricane intensity and structures on vertical resolution and time-step size
NASA Astrophysics Data System (ADS)
Zhang, Da-Lin; Wang, Xiaoxue
2003-09-01
In view of the growing interests in the explicit modeling of clouds and precipitation, the effects of varying vertical resolution and time-step sizes on the 72-h explicit simulation of Hurricane Andrew (1992) are studied using the Pennsylvania State University/National Center for Atmospheric Research (PSU/NCAR) mesoscale model (i.e., MM5) with the finest grid size of 6 km. It is shown that changing vertical resolution and time-step size has significant effects on hurricane intensity and inner-core cloud/precipitation, but little impact on the hurricane track. In general, increasing vertical resolution tends to produce a deeper storm with lower central pressure and stronger three-dimensional winds, and more precipitation. Similar effects, but to a less extent, occur when the time-step size is reduced. It is found that increasing the low-level vertical resolution is more efficient in intensifying a hurricane, whereas changing the upper-level vertical resolution has little impact on the hurricane intensity. Moreover, the use of a thicker surface layer tends to produce higher maximum surface winds. It is concluded that the use of higher vertical resolution, a thin surface layer, and smaller time-step sizes, along with higher horizontal resolution, is desirable to model more realistically the intensity and inner-core structures and evolution of tropical storms as well as the other convectively driven weather systems.
The Influence of Small Class Size, Duration, Intensity, and Heterogeneity on Head Start Fade
ERIC Educational Resources Information Center
Huss, Christopher D.
2010-01-01
The researcher conducted a nonexperimental study to investigate and analyze the influence of reduced class sizes, intensity (all day and every day), duration (five years), and heterogeneity (random class assignment) on the Head Start Fade effect. The researcher employed retrospective data analysis using a longitudinal explanatory design on data…
Winter grazing can reduce wildfire size, intensity, and behavior in a shrub-grassland
USDA-ARS?s Scientific Manuscript database
1. An increase in mega-fires and wildfires in general is a global issue that is expected to become worse with climate change. Fuel treatments are often recommended to decrease the risk, size, intensity, and severity of wildfires; however, the extensive nature of rangelands limits the use of many po...
McMorris, Terry; Sproule, John; Turner, Anthony; Hale, Beverley J
2011-03-01
The purpose of this study was to compare, using meta-analytic techniques, the effect of acute, intermediate intensity exercise on the speed and accuracy of performance of working memory tasks. It was hypothesized that acute, intermediate intensity exercise would have a significant beneficial effect on response time and that effect sizes for response time and accuracy data would differ significantly. Random-effects meta-analysis showed a significant, beneficial effect size for response time, g=-1.41 (p<0.001) but a significant detrimental effect size, g=0.40 (p<0.01), for accuracy. There was a significant difference between effect sizes (Z(diff)=3.85, p<0.001). It was concluded that acute, intermediate intensity exercise has a strong beneficial effect on speed of response in working memory tasks but a low to moderate, detrimental one on accuracy. There was no support for a speed-accuracy trade-off. It was argued that exercise-induced increases in brain concentrations of catecholamines result in faster processing but increases in neural noise may negatively affect accuracy. 2010 Elsevier Inc. All rights reserved.
Laser cooling of nuclear spin 0 alkali 78Rb
NASA Astrophysics Data System (ADS)
Behr, J. A.; Gorelov, A.; Anholm, M.
2015-05-01
The textbook example for sub-Doppler cooling is a J = 1/2 I = 0 alkali atom in lin ⊥ lin molasses. In the σ+ σ- configuration of a standard MOT, the main sub-Doppler cooling mechanism relies on changing alignment (MF2 population) with the summed linear polarization orientation, but there is no such variation in AC Stark shift for F = 1/2. We have nevertheless looked for signs of sub-Doppler cooling by trapping I = 0 78Rb in a standard MOT and measuring the cloud size as a function of laser detuning and intensity. The 78Rb cloud size does not change significantly with lowered intensity, and expands slightly with detuning, consistent with minimal to no sub-Doppler cooling. Our geometry does show the well-known substantially smaller cloud size with detuning and intensity for I = 3/2 87Rb. Maintaining an I = 0 alkali cloud size with lowered intensity will help our planned β- ν correlation experiments in 38mK decay by suppressing possible production of photoassisted dimers. Supported by NSERC and NRC Canada through TRIUMF.
Impact of traffic intensity and pavement aggregate size on road dust particles loading
NASA Astrophysics Data System (ADS)
Amato, F.; Pandolfi, M.; Alastuey, A.; Lozano, A.; Contreras González, J.; Querol, X.
2013-10-01
Road dust emissions severely hamper PM10 urban air quality and their burden is expected to increase relatively to primary motor exhaust emissions. Beside the large influence of climate and meteorology, the emission potential varies widely also from one road to another due to numerous factors such as traffic conditions, pavement type and external sources. Nevertheless none of these factors is sufficiently known for a reliable description in emission modelling and for decision making in air quality management. In this study we carried out intensive road dust measurement campaigns in South Spain, with the aim of investigating the relationship between emission potential (i.e. road dust load) and traffic intensity, pavement aggregate size and distance from braking zones. Results indicate that, while no impact from braking activity can be drawn on the bulk road dust mass, an increase in traffic intensity or mean pavement aggregate size clearly reduce the single vehicle emission potential.
Fienen, Michael N.; Selbig, William R.
2012-01-01
A new sample collection system was developed to improve the representation of sediment entrained in urban storm water by integrating water quality samples from the entire water column. The depth-integrated sampler arm (DISA) was able to mitigate sediment stratification bias in storm water, thereby improving the characterization of suspended-sediment concentration and particle size distribution at three independent study locations. Use of the DISA decreased variability, which improved statistical regression to predict particle size distribution using surrogate environmental parameters, such as precipitation depth and intensity. The performance of this statistical modeling technique was compared to results using traditional fixed-point sampling methods and was found to perform better. When environmental parameters can be used to predict particle size distributions, environmental managers have more options when characterizing concentrations, loads, and particle size distributions in urban runoff.
NASA Astrophysics Data System (ADS)
Pedrozo-Acuña, A.; Magos-Hernández, J. A.; Sánchez-Peralta, J. A.; Blanco-Figueroa, J.; Breña-Naranjo, J. A.
2017-12-01
This contribution presents a real-time system for issuing warnings of intense precipitation events during major storms, developed for Mexico City, Mexico. The system is based on high-temporal resolution (Dt=1min) measurements of precipitation in 10 different points within the city, which report variables such as intensity, number of raindrops, raindrop size, kinetic energy, fall velocity, etc. Each one of these stations, is comprised of an optical disdrometer to measure size and fall velocity of hydrometeors, a solar panel to guarantee an uninterrupted power supply, a wireless broadband access to internet, and a resource constrained device known as Raspberry Pi3 for the processing, storage and sharing of the sensor data over the world wide web. The self-made developed platform follows a component-based system paradigm allowing users to implement custom algorithms and models depending on application requirements. The system is in place since July 2016, and continuous measurements of rainfall in real-time are published over the internet through the webpage www.oh-iiunam.mx. Additionally, the developed platform for the data collection and management interacts with the social network known as Twitter to enable real-time warnings of precipitation events. Key contribution of this development is the design and implementation of a scalable, easy to use, interoperable platform that facilitates the development of real-time precipitation sensor networks and warnings. The system is easy to implement and could be used as a prototype for systems in other regions of the world.
Sherrouse, Benson C.; Hester, David J.; Wein, Anne M.
2008-01-01
The Multi-Hazards Demonstration Project (MHDP) is a collaboration between the U.S. Geological Survey (USGS) and various partners from the public and private sectors and academia, meant to improve Southern California's resiliency to natural hazards (Jones and others, 2007). In support of the MHDP objectives, the ShakeOut Scenario was developed. It describes a magnitude 7.8 (M7.8) earthquake along the southernmost 300 kilometers (200 miles) of the San Andreas Fault, identified by geoscientists as a plausible event that will cause moderate to strong shaking over much of the eight-county (Imperial, Kern, Los Angeles, Orange, Riverside, San Bernardino, San Diego, and Ventura) Southern California region. This report contains an exposure and sensitivity analysis of small businesses in terms of labor and employment statistics. Exposure is measured as the absolute counts of labor market variables anticipated to experience each level of Instrumental Intensity (a proxy measure of damage). Sensitivity is the percentage of the exposure of each business establishment size category to each Instrumental Intensity level. The analysis concerns the direct effect of the earthquake on small businesses. The analysis is inspired by the Bureau of Labor Statistics (BLS) report that analyzed the labor market losses (exposure) of a M6.9 earthquake on the Hayward fault by overlaying geocoded labor market data on Instrumental Intensity values. The method used here is influenced by the ZIP-code-level data provided by the California Employment Development Department (CA EDD), which requires the assignment of Instrumental Intensities to ZIP codes. The ZIP-code-level labor market data includes the number of business establishments, employees, and quarterly payroll categorized by business establishment size.
Laser-driven Ion Acceleration using Nanodiamonds
NASA Astrophysics Data System (ADS)
D'Hauthuille, Luc; Nguyen, Tam; Dollar, Franklin
2016-10-01
Interactions of high-intensity lasers with mass-limited nanoparticles enable the generation of extremely high electric fields. These fields accelerate ions, which has applications in nuclear medicine, high brightness radiography, as well as fast ignition for inertial confinement fusion. Previous studies have been performed with ensembles of nanoparticles, but this obscures the physics of the interaction due to the wide array of variables in the interaction. The work presented here looks instead at the interactions of a high intensity short pulse laser with an isolated nanodiamond. Specifically, we studied the effect of nanoparticle size and intensity of the laser on the interaction. A novel target scheme was developed to isolate the nanodiamond. Particle-in-cell simulations were performed using the EPOCH framework to show the sheath fields and resulting energetic ion beams.
NASA Astrophysics Data System (ADS)
Ivanova, Violeta M.; Sousa, Rita; Murrihy, Brian; Einstein, Herbert H.
2014-06-01
This paper presents results from research conducted at MIT during 2010-2012 on modeling of natural rock fracture systems with the GEOFRAC three-dimensional stochastic model. Following a background summary of discrete fracture network models and a brief introduction of GEOFRAC, the paper provides a thorough description of the newly developed mathematical and computer algorithms for fracture intensity, aperture, and intersection representation, which have been implemented in MATLAB. The new methods optimize, in particular, the representation of fracture intensity in terms of cumulative fracture area per unit volume, P32, via the Poisson-Voronoi Tessellation of planes into polygonal fracture shapes. In addition, fracture apertures now can be represented probabilistically or deterministically whereas the newly implemented intersection algorithms allow for computing discrete pathways of interconnected fractures. In conclusion, results from a statistical parametric study, which was conducted with the enhanced GEOFRAC model and the new MATLAB-based Monte Carlo simulation program FRACSIM, demonstrate how fracture intensity, size, and orientations influence fracture connectivity.
Propagation of intense short laser pulses in the atmosphere.
Sprangle, P; Peñano, J R; Hafizi, B
2002-10-01
The propagation of short, intense laser pulses in the atmosphere is investigated theoretically and numerically. A set of three-dimensional (3D), nonlinear propagation equations is derived, which includes the effects of dispersion, nonlinear self-focusing, stimulated molecular Raman scattering, multiphoton and tunneling ionization, energy depletion due to ionization, relativistic focusing, and ponderomotively excited plasma wakefields. The instantaneous frequency spread along a laser pulse in air, which develops due to various nonlinear effects, is analyzed and discussed. Coupled equations for the power, spot size, and electron density are derived for an intense ionizing laser pulse. From these equations we obtain an equilibrium for a single optical-plasma filament, which involves a balancing between diffraction, nonlinear self-focusing, and plasma defocusing. The equilibrium is shown to require a specific distribution of power along the filament. It is found that in the presence of ionization a self-guided optical filament is not realizable. A method for generating a remote spark in the atmosphere is proposed, which utilizes the dispersive and nonlinear properties of air to cause a low-intensity chirped laser pulse to compress both longitudinally and transversely. For optimally chosen parameters, we find that the transverse and longitudinal focal lengths can be made to coincide, resulting in rapid intensity increase, ionization, and white light generation in a localized region far from the source. Coupled equations for the laser spot size and pulse duration are derived, which can describe the focusing and compression process in the low-intensity regime. More general examples involving beam focusing, compression, ionization, and white light generation near the focal region are studied by numerically solving the full set of 3D, nonlinear propagation equations.
Intensity distribution of the x ray source for the AXAF VETA-I mirror test
NASA Technical Reports Server (NTRS)
Zhao, Ping; Kellogg, Edwin M.; Schwartz, Daniel A.; Shao, Yibo; Fulton, M. Ann
1992-01-01
The X-ray generator for the AXAF VETA-I mirror test is an electron impact X-ray source with various anode materials. The source sizes of different anodes and their intensity distributions were measured with a pinhole camera before the VETA-I test. The pinhole camera consists of a 30 micrometers diameter pinhole for imaging the source and a Microchannel Plate Imaging Detector with 25 micrometers FWHM spatial resolution for detecting and recording the image. The camera has a magnification factor of 8.79, which enables measuring the detailed spatial structure of the source. The spot size, the intensity distribution, and the flux level of each source were measured with different operating parameters. During the VETA-I test, microscope pictures were taken for each used anode immediately after it was brought out of the source chamber. The source sizes and the intensity distribution structures are clearly shown in the pictures. They are compared and agree with the results from the pinhole camera measurements. This paper presents the results of the above measurements. The results show that under operating conditions characteristic of the VETA-I test, all the source sizes have a FWHM of less than 0.45 mm. For a source of this size at 528 meters away, the angular size to VETA is less than 0.17 arcsec which is small compared to the on ground VETA angular resolution (0.5 arcsec, required and 0.22 arcsec, measured). Even so, the results show the intensity distributions of the sources have complicated structures. These results were crucial for the VETA data analysis and for obtaining the on ground and predicted in orbit VETA Point Response Function.
Peng, Song; Zhang, Lian; Hu, Liang; Chen, Jinyun; Ju, Jin; Wang, Xi; Zhang, Rong; Wang, Zhibiao; Chen, Wenzhi
2015-04-01
The aim of this article is to analyze factors affecting sonication dose and build a dosimetry model of high-intensity focused ultrasound (HIFU) ablation for uterine fibroids. Four hundred and three patients with symptomatic uterine fibroids who underwent HIFU were retrospectively analyzed. The energy efficiency factor (EEF) was set as dependent variable, and the factors possibly affecting sonication dose included age, body mass index, size of uterine fibroid, abdominal wall thickness, the distance from uterine fibroid dorsal side to sacrum, the distance from uterine fibroid ventral side to skin, location of uterus, location of uterine fibroids, type of uterine fibroids, abdominal wall scar, signal intensity on T2-weighted imaging (T2WI), and enhancement type on T1-weighted imaging (T1WI) were set as predictors to build a multiple regression model. The size of uterine fibroid, distance from fibroid ventral side to skin, location of uterus, location of uterine fibroids, type of uterine fibroids, signal intensity on T2WI, and enhancement type on T1WI had a linear correlation with EEF. The distance from fibroid ventral side to skin, enhancement type on T1WI, size of uterine fibroid, and signal intensity on T2WI were eventually incorporated into the dosimetry model. The distance from fibroid ventral side to skin, enhancement type on T1WI, size of uterine fibroid, and signal intensity on T2WI can be used as dosimetric predictors for HIFU for uterine fibroids.
Toward the development of erosion-free ultrasonic cavitation cleaning with gas-supersaturated water
NASA Astrophysics Data System (ADS)
Yamashita, Tatsuya; Ando, Keita
2015-11-01
In ultrasonic cleaning, contaminant particles attached at target surfaces are removed by liquid flow or acoustic waves that are induced by acoustic cavitation bubbles. However, the inertial collapse of such bubbles often involve strong shock emission or water hammer by re-entrant jets, thereby giving rise to material erosion. Here, we aim at developing an erosion-free ultrasonic cleaning technique with the aid of gas-supersaturated water. The key idea is that (gaseous) cavitation is triggered easily even with low-intensity sonication in water where gases are dissolved beyond Henry's saturation limit, allowing us to buffer violent bubble collapse. In this presentation, we report on observations of the removal of micron/submicron-sized particles attached at glass surfaces by the action of gaseous cavitation bubbles under low-intensity sonication.
Frongillo, Edward A; Nguyen, Phuong H; Saha, Kuntal K; Sanghvi, Tina; Afsana, Kaosar; Haque, Raisul; Baker, Jean; Ruel, Marie T; Rawat, Rahul; Menon, Purnima
2017-02-01
Promoting adequate nutrition through interventions to improve infant and young child feeding (IYCF) has the potential to contribute to child development. We examined whether an intensive intervention package that was aimed at improving IYCF at scale through the Alive & Thrive initiative in Bangladesh also advanced language and gross motor development, and whether advancements in language and gross motor development were explained through improved complementary feeding. A cluster-randomized design compared 2 intervention packages: intensive interpersonal counseling on IYCF, mass media campaign, and community mobilization (intensive) compared with usual nutrition counseling and mass media campaign (nonintensive). Twenty subdistricts were randomly assigned to receive either the intensive or the nonintensive intervention. Household surveys were conducted at baseline (2010) and at endline (2014) in the same communities (n = ∼4000 children aged 0-47.9 mo for each round). Child development was measured by asking mothers if their child had reached each of multiple milestones, with some observed. Linear regression accounting for clustering was used to derive difference-in-differences (DID) impact estimates, and path analysis was used to examine developmental advancement through indicators of improved IYCF and other factors. The DID in language development between intensive and nonintensive groups was 1.05 milestones (P = 0.001) among children aged 6-23.9 mo and 0.76 milestones (P = 0.038) among children aged 24-47.9 mo. For gross motor development, the DID was 0.85 milestones (P = 0.035) among children aged 6-23.9 mo. The differences observed corresponded to age- and sex-adjusted effect sizes of 0.35 for language and 0.23 for gross motor development. Developmental advancement at 6-23.9 mo was partially explained through improved minimum dietary diversity and the consumption of iron-rich food. Intensive IYCF intervention differentially advanced language and gross motor development, which was partially explained through improved complementary feeding. Measuring a diverse set of child outcomes, including functional outcomes such as child development, is important when evaluating integrated nutrition programs. This trial was registered at clinicaltrials.gov as NCT01678716. © 2017 American Society for Nutrition.
Progress in FMIT test assembly development
DOE Office of Scientific and Technical Information (OSTI.GOV)
Opperman, E.K.; Vogel, M.A.; Shen, E.J.
Research and development supporting the completed design of the Fusion Materials Irradiation Test (FMIT) Facility is continuing at the Hanford Engineering Development Laboratory (HEDL) in Richland, Washington. The FMIT, a deuteron accelerator based (d + Li) neutron source, will produce an intense flux of high energy neutrons for use in radiation damage studies of fusion reactor materials. The most intense flux magnitude of greater than 10/sup 15/ n/cm/sup 2/-s is located close to the neutron producing lithium target and is distributed within a volume about the size of an American football. The conceptual design and development of FMIT experiments calledmore » Test Assemblies has progressed over the past five years in parallel with the design of the FMIT. The paper will describe the recent accomplishments made in developing test assemblies appropriate for use in the limited volume close to the FMIT target where high neutron flux and heating rates and the associated spacial gradients significantly impact design considerations.« less
Monfared, Shabnam Khalighi; Buttler, William Tillman; Frayer, Daniel K.; ...
2015-06-11
In this paper, we report on the development of a diagnostic to provide constraints on the size of particles ejected from shocked metallic surfaces. The diagnostic is based on measurements of the intensity of laser light transmitted through a cloud of ejected particles as well as the angular distribution of scattered light, and the analysis of the resulting data is done using the Mie solution. Finally, we describe static experiments to test our experimental apparatus and present initial results of dynamic experiments on Sn targets. Improvements for future experiments are briefly discussed.
Sepúlveda, Nuno; Drakeley, Chris
2015-04-03
In the last decade, several epidemiological studies have demonstrated the potential of using seroprevalence (SP) and seroconversion rate (SCR) as informative indicators of malaria burden in low transmission settings or in populations on the cusp of elimination. However, most of studies are designed to control ensuing statistical inference over parasite rates and not on these alternative malaria burden measures. SP is in essence a proportion and, thus, many methods exist for the respective sample size determination. In contrast, designing a study where SCR is the primary endpoint, is not an easy task because precision and statistical power are affected by the age distribution of a given population. Two sample size calculators for SCR estimation are proposed. The first one consists of transforming the confidence interval for SP into the corresponding one for SCR given a known seroreversion rate (SRR). The second calculator extends the previous one to the most common situation where SRR is unknown. In this situation, data simulation was used together with linear regression in order to study the expected relationship between sample size and precision. The performance of the first sample size calculator was studied in terms of the coverage of the confidence intervals for SCR. The results pointed out to eventual problems of under or over coverage for sample sizes ≤250 in very low and high malaria transmission settings (SCR ≤ 0.0036 and SCR ≥ 0.29, respectively). The correct coverage was obtained for the remaining transmission intensities with sample sizes ≥ 50. Sample size determination was then carried out for cross-sectional surveys using realistic SCRs from past sero-epidemiological studies and typical age distributions from African and non-African populations. For SCR < 0.058, African studies require a larger sample size than their non-African counterparts in order to obtain the same precision. The opposite happens for the remaining transmission intensities. With respect to the second sample size calculator, simulation unravelled the likelihood of not having enough information to estimate SRR in low transmission settings (SCR ≤ 0.0108). In that case, the respective estimates tend to underestimate the true SCR. This problem is minimized by sample sizes of no less than 500 individuals. The sample sizes determined by this second method highlighted the prior expectation that, when SRR is not known, sample sizes are increased in relation to the situation of a known SRR. In contrast to the first sample size calculation, African studies would now require lesser individuals than their counterparts conducted elsewhere, irrespective of the transmission intensity. Although the proposed sample size calculators can be instrumental to design future cross-sectional surveys, the choice of a particular sample size must be seen as a much broader exercise that involves weighting statistical precision with ethical issues, available human and economic resources, and possible time constraints. Moreover, if the sample size determination is carried out on varying transmission intensities, as done here, the respective sample sizes can also be used in studies comparing sites with different malaria transmission intensities. In conclusion, the proposed sample size calculators are a step towards the design of better sero-epidemiological studies. Their basic ideas show promise to be applied to the planning of alternative sampling schemes that may target or oversample specific age groups.
Zhao, Bin; Yang, Tianxi; Zhang, Zhiyun; Hickey, Michael E; He, Lili
2018-03-06
The large-scale manufacturing and use of titanium dioxide (TiO 2 ) particles in food and consumer products significantly increase the likelihood of human exposure and release into the environment. We present a simple and innovative approach to rapidly identify the type (anatase or rutile), as well as to estimate, the size and concentration of TiO 2 particles using Raman spectroscopy and surface-enhanced Raman spectroscopy (SERS). The identification and discrimination of rutile and anatase were based on their intrinsic Raman signatures. The concentration of the TiO 2 particles was determined based on Raman peak intensity. Particle sizes were estimated based on the ratio between the Raman intensity of TiO 2 and the SERS intensity of myricetin bound to the nanoparticles (NPs), which was proven to be independent of TiO 2 nanoparticle concentrations. The ratio that was calculated from the 100 nm particles was used as a cutoff value when estimating the presence of nanosized particles within a mixture. We also demonstrated the practical use of this approach when determining the type, concentration, and size of E171: a mixture that contains TiO 2 particles of various sizes which are commonly used in many food products as food additives. The presence of TiO 2 anatase NPs in E171 was confirmed using the developed approach and was validated by transmission electron micrographs. TiO 2 presence in pond water was also demonstrated to be an analytical capability of this method. Our approach shows great promise for the rapid screening of nanosized rutile and anatase TiO 2 particles in complex matrixes. This approach will strongly improve the measurement of TiO 2 quality during production, as well as the survey capacity and risk assessment of TiO 2 NPs in food, consumer goods, and environmental samples.
NASA Technical Reports Server (NTRS)
Fenton, D. L.; Purcell, R. Y.; Hrdina, D.; Knutson, E. O.
1980-01-01
The coefficient for the washout from a rocket exhaust cloud of HCl generated by the combustion of an ammonium perchlorate-based solid rocket propellant such as that to be used for the Space Shuttle Booster is determined. A mathematical model of HCl scavenging by rain is developed taking into account rain droplet size, fall velocity and concentration under various rain conditions, partitioning of exhaust HCl between liquid and gaseous phases, the tendency of HCl to promote water vapor condensation and the concentration and size of droplets within the exhaust cloud. The washout coefficient is calculated as a function of total cloud water content, total HCl content at 100% relative humidity, condensation nuclei concentration and rain intensity. The model predictions are compared with experimental results obtained in scavenging tests with solid rocket exhaust and raindrops of different sizes, and the large reduction in washout coefficient at high relative humidities predicted by the model is not observed. A washout coefficient equal to 0.0000512 times the -0.176 power of the mass concentration of HCl times the 0.773 power of the rainfall intensity is obtained from the experimental data.
Laboratory Reflectance Spectra in the Middle-infrared: Effects of Grain Size on Spectral Features
NASA Astrophysics Data System (ADS)
Le Bras, A.; Erard, S.; Fulchignoni, M.
2000-10-01
Since spectral mineral features are sensitive to surface parameters, interpretation of remote-sensing asteroids spectra in terms of mineral composition is not easy nor unique, and laboratory spectra are needed in order to understand the influence of each parameter. We developped an experimental program at IAS, using the 2.5-120 microns interferometer spectrometer, to study the influence of surface parameters on mineral features. We present here the results obtained variing the grain size. We studied grain size effects with two types of terrestrial rocks: anorthosite (bright) and basalte (dark) in the 2-40 microns range. We observed variations of the spectral contrast with grain size, shifts in wavelengths and variations of the intensity of some characteristic spectral features, and appearence of transparency features at wavelengths longer than 8 microns.
ERIC Educational Resources Information Center
Hasselhorn, Marcus; Linke-Hasselhorn, Kathrin
2013-01-01
Eight six-year old German children with development disabilities regarding such number competencies as have been demonstrated to be among the most relevant precursor skills for the acquisition of elementary mathematics received intensive training with the program "Mengen, zählen, Zahlen" ["quantities, counting, numbers"] (MZZ,…
C.H. Strauss
1991-01-01
Production costs for short rotation, intensive culture (SRIC) Populus biomass were developed from commercial-sized plantations under investigation throughout the eastern U.S. Populus hybrid planted on good quality plantation sites at a density of 850 cuttings/acre was projected to yield an average of 7 ovendry (OD) tons/acre/year....
Development of Adaptive Tilt Tracker that Utilizes QUAD-cell Detector to Track Extended Objects
2014-03-17
telescopes. When incident light encounters the atmosphere , it experiences a turbulent medium that distorts optical wavefronts. Without the AO...fluctuations which randomize optical path lengths. Figure 2 - The temporal and spatial aspects of atmospheric turbulence [6] Consider...the PTS are determined by atmospheric turbulence , optical set-up, and object characteristics such as size, shape, motion, and intensity
Prediction of treatment outcome in soft tissue sarcoma based on radiologically defined habitats
NASA Astrophysics Data System (ADS)
Farhidzadeh, Hamidreza; Chaudhury, Baishali; Zhou, Mu; Goldgof, Dmitry B.; Hall, Lawrence O.; Gatenby, Robert A.; Gillies, Robert J.; Raghavan, Meera
2015-03-01
Soft tissue sarcomas are malignant tumors which develop from tissues like fat, muscle, nerves, fibrous tissue or blood vessels. They are challenging to physicians because of their relative infrequency and diverse outcomes, which have hindered development of new therapeutic agents. Additionally, assessing imaging response of these tumors to therapy is also difficult because of their heterogeneous appearance on magnetic resonance imaging (MRI). In this paper, we assessed standard of care MRI sequences performed before and after treatment using 36 patients with soft tissue sarcoma. Tumor tissue was identified by manually drawing a mask on contrast enhanced images. The Otsu segmentation method was applied to segment tumor tissue into low and high signal intensity regions on both T1 post-contrast and T2 without contrast images. This resulted in four distinctive subregions or "habitats." The features used to predict metastatic tumors and necrosis included the ratio of habitat size to whole tumor size and components of 2D intensity histograms. Individual cases were correctly classified as metastatic or non-metastatic disease with 80.55% accuracy and for necrosis ≥ 90 or necrosis <90 with 75.75% accuracy by using meta-classifiers which contained feature selectors and classifiers.
Vesicle sizing by static light scattering: a Fourier cosine transform approach
NASA Astrophysics Data System (ADS)
Wang, Jianhong; Hallett, F. Ross
1995-08-01
A Fourier cosine transform method, based on the Rayleigh-Gans-Debye thin-shell approximation, was developed to retrieve vesicle size distribution directly from the angular dependence of scattered light intensity. Its feasibility for real vesicles was partially tested on scattering data generated by the exact Mie solutions for isotropic vesicles. The noise tolerance of the method in recovering unimodal and biomodal distributions was studied with the simulated data. Applicability of this approach to vesicles with weak anisotropy was examined using Mie theory for anisotropic hollow spheres. A primitive theory about the first four moments of the radius distribution about the origin, excluding the mean radius, was obtained as an alternative to the direct retrieval of size distributions.
Fully anharmonic IR and Raman spectra of medium-size molecular systems: accuracy and interpretation†
Barone, Vincenzo; Biczysko, Malgorzata; Bloino, Julien
2015-01-01
Computation of full infrared (IR) and Raman spectra (including absolute intensities and transition energies) for medium- and large-sized molecular systems beyond the harmonic approximation is one of the most interesting challenges of contemporary computational chemistry. Contrary to common beliefs, low-order perturbation theory is able to deliver results of high accuracy (actually often better than those issuing from current direct dynamics approaches) provided that anharmonic resonances are properly managed. This perspective sketches the recent developments in our research group toward the development a robust and user-friendly virtual spectrometer rooted into the second-order vibrational perturbation theory (VPT2) and usable also by non-specialists essentially as a black-box procedure. Several examples are explicitly worked out in order to illustrate the features of our computational tool together with the most important ongoing developments. PMID:24346191
Felling and skidding productivity and harvesting cost in southern pine forests
R.A. Kluender; B.J. Stokes
1996-01-01
Sixteen stands were harvested at various levels of basal area removed (intensity). Chainsaw felling productivity was more sensitive to stem diameter than harvest intensity. Skidding productivity was highest when removing large trees at high intensity. Harvesting cost was more sensitive to stem size than harvest intensity, although harvest intensity was a very important...
Wu, Xinliang; Wei, Yujie; Wang, Junguang; Xia, Jinwen; Cai, Chongfa; Wei, Zhiyuan
2018-04-15
Soil erosion poses a major threat to the sustainability of natural ecosystems. The main objective of this study was to investigate the effects of soil type and rainfall intensity on sheet erosion processes (hydrological, erosional processes and sediment characteristics) from temperate to tropical climate. Field plot experiments were conducted under pre-wetted bare fallow condition for five soil types (two Luvisols, an Alisol, an Acrisol and a Ferralsol) with heavy textures (silty clay loam, silty clay and clay) derived separately from loess deposits, quaternary red clays and basalt in central-south China. Rainfall simulations were performed at two rainfall intensities (45 and 90mmh -1 ) and lasted one hour after runoff generation. Runoff coefficient, sediment concentration, sediment yield rate and sediment effective size distribution were determined at 3-min intervals. Runoff temporal variations were similar at the high rainfall intensity, but exhibited a remarkable difference at the low rainfall intensity among soil types except for tropical Ferralsol. Illite was positively correlated with runoff coefficient (p<0.05). Rainfall intensity significantly contributed to the erosional process (p<0.001). Sediment concentration and yield rate were the smallest for the tropical Ferralsol and sediment concentration was the largest for the temperate Luvisol. The regimes (transport and detachment) limiting erosion varied under the interaction of rainfall characteristics (intensity and duration) and soil types, with amorphous iron oxides and bulk density jointly enhancing soil resistance to erosive forces (Adj-R 2 >88%, p<0.001). Sediment size was dominated by <0.1mm size fraction for the Luvisols and bimodally distributed with the peaks at <0.1mm and 1-0.5mm size for the other soil types. Exchangeable sodium decreased sediment size while rainfall intensity and clay content increased it (Adj-R 2 =96%, p<0.01). These results allow to better understand the climate effect on erosion processes at the spatial-temporal scale from the perspective of soil properties. Copyright © 2017 Elsevier B.V. All rights reserved.
Enhanced nanoparticle size control by extending LaMer’s mechanism
Vreeland, Erika C.; Watt, John; Schober, Gretchen B.; ...
2015-08-17
The synthesis of well-defined nanoparticle materials has been an area of intense investigation, but size control in nanoparticle syntheses is largely empirical. Here, we introduce a general method for fine size control in the synthesis of nanoparticles by establishing steady state growth conditions through the continuous, controlled addition of precursor, leading to a uniform rate of particle growth. This approach, which we term the “extended LaMer mechanism” allows for reproducibility in particle size from batch to batch as well as the ability to predict nanoparticle size by monitoring the early stages of growth. We have demonstrated this method by applyingmore » it to a challenging synthetic system: magnetite nanoparticles. To facilitate this reaction, we have developed a reproducible method for synthesizing an iron oleate precursor that can be used without purification. As a result, we then show how such fine size control affects the performance of magnetite nanoparticles in magnetic hyperthermia.« less
NASA Astrophysics Data System (ADS)
Takayabu, Yukari; Hamada, Atsushi; Mori, Yuki; Murayama, Yuki; Liu, Chuntao; Zipser, Edward
2015-04-01
While extreme rainfall has a huge impact upon human society, the characteristics of the extreme precipitation vary from region to region. Seventeen years of three dimensional precipitation measurements from the space-borne precipitation radar equipped with the Tropical Precipitation Measurement Mission satellite enabled us to describe the characteristics of regional extreme precipitation globally. Extreme rainfall statistics are based on rainfall events defined as a set of contiguous PR rainy pixels. Regional extreme rainfall events are defined as those in which maximum near-surface rainfall rates are higher than the corresponding 99.9th percentile in each 2.5degree x2.5degree horizontal resolution grid. First, regional extreme rainfall is characterized in terms of its intensity and event size. Regions of ''intense and extensive'' extreme rainfall are found mainly over oceans near coastal areas and are likely associated with tropical cyclones and convective systems associated with the establishment of monsoons. Regions of ''intense but less extensive'' extreme rainfall are distributed widely over land and maritime continents, probably related to afternoon showers and mesoscale convective systems. Regions of ''extensive but less intense'' extreme rainfall are found almost exclusively over oceans, likely associated with well-organized mesoscale convective systems and extratropical cyclones. Secondly, regional extremes in terms of surface rainfall intensity and those in terms of convection height are compared. Conventionally, extremely tall convection is considered to contribute the largest to the intense rainfall. Comparing probability density functions (PDFs) of 99th percentiles in terms of the near surface rainfall intensity in each regional grid and those in terms of the 40dBZ echo top heights, it is found that heaviest precipitation in the region is not associated with tallest systems, but rather with systems with moderate heights. Interestingly, this separation of extremely heavy precipitation from extremely tall convection is found to be quite universal, irrespective of regions. Rainfall characteristics and environmental conditions both indicate the importance of warm-rain processes in producing extreme rainfall rates. Thus it is demonstrated that, even in regions where severe convective storms are representative extreme weather events, the heaviest rainfall events are mostly associated with less intense convection. Third, the size effect of rainfall events on the precipitation intensity is investigated. Comparisons of normalized PDFs of foot-print size rainfall intensity for different sizes of rainfall events show that footprint-scale extreme rainfall becomes stronger as the rainfall events get larger. At the same time, stratiform ratio in area as well as in rainfall amount increases with the size, confirming larger sized features are more organized systems. After all, it is statistically shown that organization of precipitation not only brings about an increase in extreme volumetric rainfall but also an increase in probability of the satellite footprint scale extreme rainfall.
Age-related differences in muscle fatigue vary by contraction type: a meta-analysis.
Avin, Keith G; Law, Laura A Frey
2011-08-01
During senescence, despite the loss of strength (force-generating capability) associated with sarcopenia, muscle endurance may improve for isometric contractions. The purpose of this study was to perform a systematic meta-analysis of young versus older adults, considering likely moderators (ie, contraction type, joint, sex, activity level, and task intensity). A 2-stage systematic review identified potential studies from PubMed, CINAHL, PEDro, EBSCOhost: ERIC, EBSCOhost: Sportdiscus, and The Cochrane Library. Studies reporting fatigue tasks (voluntary activation) performed at a relative intensity in both young (18-45 years of age) and old (≥ 55 years of age) adults who were healthy were considered. Sample size, mean and variance outcome data (ie, fatigue index or endurance time), joint, contraction type, task intensity (percentage of maximum), sex, and activity levels were extracted. Effect sizes were (1) computed for all data points; (2) subgrouped by contraction type, sex, joint or muscle group, intensity, or activity level; and (3) further subgrouped between contraction type and the remaining moderators. Out of 3,457 potential studies, 46 publications (with 78 distinct effect size data points) met all inclusion criteria. A lack of available data limited subgroup analyses (ie, sex, intensity, joint), as did a disproportionate spread of data (most intensities ≥ 50% of maximum voluntary contraction). Overall, older adults were able to sustain relative-intensity tasks significantly longer or with less force decay than younger adults (effect size=0.49). However, this age-related difference was present only for sustained and intermittent isometric contractions, whereas this age-related advantage was lost for dynamic tasks. When controlling for contraction type, the additional modifiers played minor roles. Identifying muscle endurance capabilities in the older adult may provide an avenue to improve functional capabilities, despite a clearly established decrement in peak torque.
Size Effects in Nanoscale Structural Phenomena
NASA Astrophysics Data System (ADS)
McElhinny, Kyle Matthew
The creation of nanostructures offers the opportunity to modify and tune properties in ways inaccessible in bulk materials. A key component in this development is the introduction of size effects which reduce the physical size, dimensionality, and increase the contribution of surface effects. The size effects strongly modify the structural dynamics in nanoscale systems and leads to changes in the vibrational, electrical, and optical properties. An increased level of understanding and control of nanoscale structural dynamics will enable more precise control over nanomaterial transport properties. My work has shown that 1D spatial confinement through the creation of semiconducting nanomembranes modifies the phonon population and dispersion. X ray thermal diffuse scattering distributions show an excess in intensity for nanomembranes less than 100 nm in thickness, for phonon modes with wavevectors spanning the entire Brillouin zone. This excess intensity indicates the development of new low energy phonon modes or the softening of elastic constants. Furthermore, an additional anisotropy in the phonon dispersion is observed with a symmetry matching the direction of spatial confinement. This work has also extended x ray thermal diffuse scattering for use in studying nanomaterials. In electro- and photoactive monolayers a structural reconfiguration can be produced by external optical stimuli. I have developed an electro and photoactive molecular monolayers on oxide surfaces. Using x ray reflectivity, I have evaluated the organization and reconfiguration of molecular monolayers deposited by Langmuir Blodgett technique. I have designed and probed the reconfiguration of optically reconfigurable monolayers of azobenzene donor molecules on semiconducting surfaces. These monolayers reconfigure through a cooperative switching process leading to the development of large isomeric domains. This work represents an advancement in the interpretation of x ray reflectivity from molecular monolayers and inhomogeneous surfaces. The growth 2D materials depends on the interactions between the substrate and the 2D material. I have studied the competition between kinetics and surface energetics which lead to a faceted Ge surface during the growth of Graphene nanoribbons. As part of this work, I have developed new methodologies for interpreting x ray reflectivity patterns from surfaces with multiple reflections. A systematic analysis of the temperature dependence of the faceting process indicates that the process is thermodynamically dominated at high temperatures.
Carten, R.B.; Geraghty, E.P.; Walker, B.M.
1988-01-01
The Henderson porphyry molybdenum deposit was formed by the superposition of coupled alteration and mineralization events, of varying intensity and size, that were associated with each of at least 11 intrusions. Deposition of molybdenite was accompanied by time-equivalent silicic and potassic alteration. High-temperature alteration and mineralization are spatially and temporally linked to the crystallization of compositionally zoned magma in the apex of stocks. Differences in hydrothermal features associated with each intrusion (e.g., mass of ore, orientation and type of veins, density of veins, and intensity of alteration) correlate with differences in primary igneous features (e.g., composition, texture, morphology, and size). The systematic relations between hydrothermal and magmatic features suggest that primary magma compositions, including volatile contents, largely control the geometry, volume, level of emplacement, and mechanisms of crystallization of stocks. These elements in turn govern the orientations and densities of fractures, which ultimately determine the distribution patterns of hydrothermal alteration and mineralization. -from Authors
Effect of the Initial Vortex Size on Intensity Change in the WRF-ROMS Coupled Model
NASA Astrophysics Data System (ADS)
Zhao, Xiaohui; Chan, Johnny C. L.
2017-12-01
Numerous studies have demonstrated that the tropical cyclone (TC) induced sea surface temperature (SST) cooling strongly depends on the preexisting oceanic condition and TC characteristics. However, very few focused on the correlation of SST cooling and the subsequent intensity with TC size. Therefore, a series of idealized numerical experiments are conducted using the Weather Research Forecasting (WRF) model coupled with the Regional Ocean Model System (ROMS) model to understand how the vortex size is related to SST cooling and subsequent intensity changes of a stationary TC-like vortex. In the uncoupled experiments, the radius of maximum wind (RMW) and size (radius of gale-force wind (R17)) both depend on the initial size within the 72 h simulation. The initially small vortex is smaller than the medium and large vortices throughout its life cycle and is the weakest. In other words, thermodynamic processes do not contribute as much to the R17 change as the dynamic processes proposed (e.g., angular momentum transport) in previous studies. In the coupled experiments, the area-averaged SST cooling induced by medium and large TCs within the inner-core region is comparable due to the similar surface winds and thus mixing in the ocean. Although a stronger SST cooling averaged within a larger region outside the inner-core is induced by the larger TC, the intensity of the larger TC is more intense. This is because that the enthalpy flux in the inner-core region is higher in the larger TC than that in the medium and small TCs.
NASA Astrophysics Data System (ADS)
Carvalho, Sílvia C. P.; de Lima, João L. M. P.; de Lima, M. Isabel P.
2013-04-01
Rainfall simulators can be a powerful tool to increase our understanding of hydrological and geomorphological processes. Nevertheless, rainfall simulators' design and operation might be rather demanding, for achieving specific rainfall intensity distributions and drop characteristics. The pressurized simulators have some advantages over the non-pressurized simulators: drops do not rely on gravity to reach terminal velocity, but are sprayed out under pressure; pressurized simulators also yield a broad range of drop sizes in comparison with drop-formers simulators. The main purpose of this study was to explore in the laboratory the potential of combining spray nozzle simulators with meshes in order to change rainfall characteristics (rainfall intensity and diameters and fall speed of drops). Different types of spray nozzles were tested, such as single full-cone and multiple full-cone nozzles. The impact of the meshes on the simulated rain was studied by testing different materials (i.e. plastic and steel meshes), square apertures and wire thicknesses, and different vertical distances between the nozzle and the meshes underneath. The diameter and fall speed of the rain drops were measured using a Laser Precipitation Monitor (Thies Clima). The rainfall intensity range and coefficients of uniformity of the sprays and the drop size distribution, fall speed and kinetic energy were analysed. Results show that when meshes intercept drop trajectories the spatial distribution of rainfall intensity and the drop size distribution are affected. As the spray nozzles generate typically small drop sizes and narrow drop size distributions, meshes can be used to promote the formation of bigger drops and random their landing positions.
Advanced methods for processing ceramics
DOE Office of Scientific and Technical Information (OSTI.GOV)
Carter, W.B.
1997-04-01
Combustion chemical vapor deposition (combustion CVD) is being developed for the deposition of high temperature oxide coatings. The process is being evaluated as an alternative to more capital intensive conventional coating processes. The thrusts during this reporting period were the development of the combustion CVD process for depositing lanthanum monazite, the determination of the influence of aerosol size on coating morphology, the incorporation of combustion CVD coatings into thermal barrier coatings (TBCs) and related oxidation research, and continued work on the deposition of zirconia-yttria coatings.
Body size limits dim-light foraging activity in stingless bees (Apidae: Meliponini).
Streinzer, Martin; Huber, Werner; Spaethe, Johannes
2016-10-01
Stingless bees constitute a species-rich tribe of tropical and subtropical eusocial Apidae that act as important pollinators for flowering plants. Many foraging tasks rely on vision, e.g. spatial orientation and detection of food sources and nest entrances. Meliponini workers are usually small, which sets limits on eye morphology and thus quality of vision. Limitations are expected both on acuity, and thus on the ability to detect objects from a distance, as well as on sensitivity, and thus on the foraging time window at dusk and dawn. In this study, we determined light intensity thresholds for flight under dim light conditions in eight stingless bee species in relation to body size in a Neotropical lowland rainforest. Species varied in body size (0.8-1.7 mm thorax-width), and we found a strong negative correlation with light intensity thresholds (0.1-79 lx). Further, we measured eye size, ocelli diameter, ommatidia number, and facet diameter. All parameters significantly correlated with body size. A disproportionately low light intensity threshold in the minute Trigonisca pipioli, together with a large eye parameter P eye suggests specific adaptations to circumvent the optical constraints imposed by the small body size. We discuss the implications of body size in bees on foraging behavior.
USDA-ARS?s Scientific Manuscript database
A recent study by Davies et al. sought to test whether winter grazing could reduce wildfire size, fire behavior and intensity metrics, and fire-induced plant mortality in shrub-grasslands. The authors concluded that ungrazed rangelands may experience fire-induced mortality of native perennial bunchg...
A.R. Weiskittel; R.A. Monserud; R. Rose; E.C. Turnblom; Douglas A. Maguire
2006-01-01
Intensive management may adversely affect lumber yield and quality by increasing knot size and creating a more conical stem form with a greater average rate of taper. This study was initiated to examine the impact of management on simulated lumber yield and quality. Stem diameter and branch size and location of 223 Pseudotsuga menziesii (Mirb.)...
Prototype for measuring pupil size changes
NASA Astrophysics Data System (ADS)
Ventura, Liliane; Pergoraro Silva, Fernando; Rossi, Giuliano; Riul, Cassius
2007-02-01
The neurological control of the visual process is extremely complex and the pupil movement plays an important role. It controls the intensity of light entering the eye, is responsible for focusing depth and avoiding undesired paracentral rays. As such factors vary along the day for each patient individually, allied to the individual answer to determined light stimulation, it is not possible to predict the pupilar size change along the day, leading to undetermined image quality of the patient for a pre-existent condition. Among the clinical and surgical procedures in order to enhance the quality of the visual system of the patient, wave-front based surgeries are performed and its efficiency is strongly dependent on the pupilar position as well as the area to be ablated. In order to predict the individual behavior of the pupil change during an ordinary routine of the patient we have been developing a system to provide means for the personal refractive surgery to be the most efficient as possible. This work presents a method for monitoring the dynamics of the pupil. The methodology presented in this work provides measurements of the patient's pupil sizes along an entire day with light intensity conditioned to the one that the patient is exposed. A prototype has been developed using an eyeglass frame, where a dichroic mirror (70% transmittance) is attached to the frame, as well as a CMOS camera and an infrared illumination system. The image of the pupil is acquired every 4 minutes, its transferring is done by wireless serial communication (RS-232) and saved in a flash memory. Image processing and pupil size determination are done later separately from monitoring. The system is under preliminary tests.
Intensity Conserving Spectral Fitting
NASA Technical Reports Server (NTRS)
Klimchuk, J. A.; Patsourakos, S.; Tripathi, D.
2015-01-01
The detailed shapes of spectral line profiles provide valuable information about the emitting plasma, especially when the plasma contains an unresolved mixture of velocities, temperatures, and densities. As a result of finite spectral resolution, the intensity measured by a spectrometer is the average intensity across a wavelength bin of non-zero size. It is assigned to the wavelength position at the center of the bin. However, the actual intensity at that discrete position will be different if the profile is curved, as it invariably is. Standard fitting routines (spline, Gaussian, etc.) do not account for this difference, and this can result in significant errors when making sensitive measurements. Detection of asymmetries in solar coronal emission lines is one example. Removal of line blends is another. We have developed an iterative procedure that corrects for this effect. It can be used with any fitting function, but we employ a cubic spline in a new analysis routine called Intensity Conserving Spline Interpolation (ICSI). As the name implies, it conserves the observed intensity within each wavelength bin, which ordinary fits do not. Given the rapid convergence, speed of computation, and ease of use, we suggest that ICSI be made a standard component of the processing pipeline for spectroscopic data.
On the development of efficient algorithms for three dimensional fluid flow
NASA Technical Reports Server (NTRS)
Maccormack, R. W.
1988-01-01
The difficulties of constructing efficient algorithms for three-dimensional flow are discussed. Reasonable candidates are analyzed and tested, and most are found to have obvious shortcomings. Yet, there is promise that an efficient class of algorithms exist between the severely time-step sized-limited explicit or approximately factored algorithms and the computationally intensive direct inversion of large sparse matrices by Gaussian elimination.
Logging costs for a trial of intensive residue removal.
Thomas C. Adams
1980-01-01
Logging costs were developed in a study of residue removal to specified levels in each of three size classes: 1/4 to 3, 3.1 to 9, and over 9 inches in diameter. These levels were determined by an interdisciplinary team during initial sale planning and represented levels that would be desired to attain without slash burning. Cable yarding was specified. This trial was...
NASA Astrophysics Data System (ADS)
Bottyán, Zsolt; Kircsi, Andrea; Szegedi, Sándor; Unger, János
2005-03-01
The climate of built-up regions differs significantly from rural regions and the most important modifying effect of urbanization on local climate is the urban temperature excess, otherwise called the urban heat island (UHI).This study examines the influence of built-up areas on the near-surface air temperature field in the case of the medium-sized city of Debrecen, Hungary. Mobile measurements were used under different weather conditions between March 2002 and March 2003. Efforts concentrated on the determination of the spatial distribution of mean maximum UHI intensity with special regard to land-use features such as built-up ratio and its areal extensions.In both (heating and non-heating) seasons the spatial distribution of the UHI intensity field showed a basically concentric shape with local anomalies. The mean maximum UHI intensity reaches more than 2.0 °C (heating season) and 2.5 °C (non-heating season) in the centre of the city. We established the relationship between the above-mentioned land-use parameters and mean maximum UHI intensity by means of multiple linear regression analysis. As the measured and predicted mean maximum UHI intensity patterns show, there is an obvious connection between the spatial distribution of urban thermal excess and the land-use parameters examined, so these parameters play a significant role in the development of the strong UHI intensity field over the city.
Angular-dependent light scattering from cancer cells in different phases of the cell cycle.
Lin, Xiaogang; Wan, Nan; Weng, Lingdong; Zhou, Yong
2017-10-10
Cancer cells in different phases of the cell cycle result in significant differences in light scattering properties. In order to harvest cancer cells in particular phases of the cell cycle, we cultured cancer cells through the process of synchronization. Flow cytometric analysis was applied to check the results of cell synchronization and prepare for light scattering measurements. Angular-dependent light scattering measurements of cancer cells arrested in the G1, S, and G2 phases have been performed. Based on integral calculations for scattering intensities from 5° to 10° and from 110° to 150°, conclusions have been reached. Clearly, the sizes of the cancer cells in different phases of the cell cycle dominated the forward scatter. Accompanying the increase of cell size with the progression of the cell cycle, the forward scattering intensity also increased. Meanwhile, the DNA content of cancer cells in every phase of the cell cycle is responsible for light scattering at large scatter angles. The higher the DNA content of cancer cells was, the greater the positive effect on the high-scattering intensity. As expected, understanding the relationships between the light scattering from cancer cells and cell cycles will aid in the development of cancer diagnoses. Also, it may assist in the guidance of antineoplastic drugs clinically.
Fracture toughness of brittle materials determined with chevron notch specimens
NASA Technical Reports Server (NTRS)
Shannon, J. L., Jr.; Bursey, R. T.; Munz, D.; Pierce, W. S.
1980-01-01
The use of chevron-notch specimens for determining the plane strain fracture toughness (K sub Ic) of brittle materials is discussed. Three chevron-notch specimens were investigated: short bar, short rod, and four-point-bend. The dimensionless stress intensity coefficient used in computing K sub Ic is derived for the short bar specimen from the superposition of ligament-dependent and ligament-independent solutions for the straight through crack, and also from experimental compliance calibrations. Coefficients for the four-point-bend specimen were developed by the same superposition procedure, and with additional refinement using the slice model of Bluhm. Short rod specimen stress intensity coefficients were determined only by experimental compliance calibration. Performance of the three chevron-notch specimens and their stress intensity factor relations were evaluated by tests on hot-pressed silicon nitride and sintered aluminum oxide. Results obtained with the short bar and the four-point-bend specimens on silicon nitride are in good agreement and relatively free of specimen geometry and size effects within the range investigated. Results on aluminum oxide were affected by specimen size and chevron-notch geometry, believed due to a rising crack growth resistance curve for the material. Only the results for the short bar specimen are presented in detail.
NASA Astrophysics Data System (ADS)
Locatello, Lisa; Pizzolon, Matteo; Rasotto, Maria Berica
2012-10-01
Colourful ornaments are traditionally evaluated as one trait. However, they could consist of several components, such as total size, colour intensity and extension, each possibly bearing its own message about one aspect of quality. Males of the blenny Salaria pavo exhibit a colourful head crest and solely care for eggs. During the breeding season, the head crest shows a yellow colouration, the intensity and relative extension of which are independent of crest size. Here, we show that: (1) carotenoids are responsible for the head crest yellow patch; (2) activating the immune system by injecting the bacterial antigen lipopolysaccharides affects both the intensity and extent of the yellow colouration; and (3) females assess males on the basis of colour patch expression. However, the response of the yellow patch to the immune challenge was dependent on head crest size. Indeed, males with a larger head crest reacted better to the simulated infection, sustaining a level of yellow patch close to pre-challenge size.
NASA Astrophysics Data System (ADS)
Guo, Yanhui; Zhou, Chuan; Chan, Heang-Ping; Wei, Jun; Chughtai, Aamer; Sundaram, Baskaran; Hadjiiski, Lubomir M.; Patel, Smita; Kazerooni, Ella A.
2013-04-01
A 3D multiscale intensity homogeneity transformation (MIHT) method was developed to reduce false positives (FPs) in our previously developed CAD system for pulmonary embolism (PE) detection. In MIHT, the voxel intensity of a PE candidate region was transformed to an intensity homogeneity value (IHV) with respect to the local median intensity. The IHVs were calculated in multiscales (MIHVs) to measure the intensity homogeneity, taking into account vessels of different sizes and different degrees of occlusion. Seven new features including the entropy, gradient, and moments that characterized the intensity distributions of the candidate regions were derived from the MIHVs and combined with the previously designed features that described the shape and intensity of PE candidates for the training of a linear classifier to reduce the FPs. 59 CTPA PE cases were collected from our patient files (UM set) with IRB approval and 69 cases from the PIOPED II data set with access permission. 595 and 800 PEs were identified as reference standard by experienced thoracic radiologists in the UM and PIOPED set, respectively. FROC analysis was used for performance evaluation. Compared with our previous CAD system, at a test sensitivity of 80%, the new method reduced the FP rate from 18.9 to 14.1/scan for the PIOPED set when the classifier was trained with the UM set and from 22.6 to 16.0/scan vice versa. The improvement was statistically significant (p<0.05) by JAFROC analysis. This study demonstrated that the MIHT method is effective in reducing FPs and improving the performance of the CAD system.
Small-angle x-ray scattering in amorphous silicon: A computational study
NASA Astrophysics Data System (ADS)
Paudel, Durga; Atta-Fynn, Raymond; Drabold, David A.; Elliott, Stephen R.; Biswas, Parthapratim
2018-05-01
We present a computational study of small-angle x-ray scattering (SAXS) in amorphous silicon (a -Si) with particular emphasis on the morphology and microstructure of voids. The relationship between the scattering intensity in SAXS and the three-dimensional structure of nanoscale inhomogeneities or voids is addressed by generating large high-quality a -Si networks with 0.1%-0.3% volume concentration of voids, as observed in experiments using SAXS and positron annihilation spectroscopy. A systematic study of the variation of the scattering intensity in the small-angle scattering region with the size, shape, number density, and the spatial distribution of the voids in the networks is presented. Our results suggest that the scattering intensity in the small-angle region is particularly sensitive to the size and the total volume fraction of the voids, but the effect of the geometry or shape of the voids is less pronounced in the intensity profiles. A comparison of the average size of the voids obtained from the simulated values of the intensity, using the Guinier approximation and Kratky plots, with that of the same from the spatial distribution of the atoms in the vicinity of void surfaces is presented.
Flowability of lignocellusic biomass powders: influence of torrefaction intensity
NASA Astrophysics Data System (ADS)
Pachón-Morales, John; Colin, Julien; Pierre, Floran; Champavert, Thibaut; Puel, François; Perré, Patrick
2017-06-01
The poor flowability of powders produced from raw lignocellulosic biomass may be an economically issue for the production of second-generation biofuels. Torrefaction is a pre-treatment step of the gasification process that improves the physical characteristics of biomass by making it more coal-like. Particularly, the loss of resilience allows a reduction of the grinding energy consumption and is likely to improve the flow behaviour of woody powders. In this study, we investigated the effect of particle size and shape distribution on flow properties (unconfined yield stress and flowability factor) of powder from raw and torrefied biomass (Picea abies). Several intensities of torrefaction were tested, and its extent was quantified by the global mass loss, chosen as synthetic indicator of torrefaction intensity (its accounts for both the temperature level and the residence time). The intensity of torrefaction shifts the particle size distribution towards smaller sizes. An effect on the circularity and aspect ratio was also observed. A strong, positive correlation was obtained between the measured flowability of biomass powders at different consolidation stresses and the intensity of heat treatment. These results confirm the interest of torrefaction as a pre-treatment step and aim to provide new knowledge on rheological properties of biomass powders.
High-intensity and resistance training and elite young athletes.
Ratel, Sébastien
2011-01-01
Although in the past resistance and high-intensity exercise training among young children was the subject of numerous controversies, it is now well-documented that this training mode is a safe and effective means of developing maximal strength, maximal power output and athletic performance in youth, provided that exercises are performed with appropriate supervision and precautions. Muscular strength and power output values measured from vertical jump and Wingate anaerobic tests are higher in elite than in non-elite young athletes and normal children, and the specific training effects on maximal power output normalised for body size are clearly more distinct before puberty. At present, there is no scientific evidence to support the view that high-intensity and/or resistance training might hinder growth and maturation in young children. Pre-pubertal growth is not adversely affected by sport at a competitive level and anthropometric factors are of importance for choice of sport in children. However, coaches, teachers and parents should be aware that unsupervised high-intensity and resistance training programmes involving maximal loads or too frequently repeated resistance exercises increase the risk of injury. Resistance training alone is an effective additional means of developing athletic performance throughout planned youth sports training programmes. Strategies for enhancing the effectiveness and safety of youth resistance and high-intensity exercise training are discussed in this chapter. Copyright © 2011 S. Karger AG, Basel.
Li, Xiao-li; An, Shu-qing; Xu, Tie-min; Liu, Yi-bo; Zhang, Li-juan; Zeng, Jiang-ping; Wang, Na
2015-06-01
The main analysis error of pressed powder pellet of carbonate comes from particle-size effect and mineral effect. So in the article in order to eliminate the particle-size effect, the ultrafine pressed powder pellet sample preparation is used to the determination of multi-elements and carbon-dioxide in carbonate. To prepare the ultrafine powder the FRITSCH planetary Micro Mill machine and tungsten carbide media is utilized. To conquer the conglomeration during the process of grinding, the wet grinding is preferred. The surface morphology of the pellet is more smooth and neat, the Compton scatter effect is reduced with the decrease in particle size. The intensity of the spectral line is varied with the change of the particle size, generally the intensity of the spectral line is increased with the decrease in the particle size. But when the particle size of more than one component of the material is decreased, the intensity of the spectral line may increase for S, Si, Mg, or decrease for Ca, Al, Ti, K, which depend on the respective mass absorption coefficient . The change of the composition of the phase with milling is also researched. The incident depth of respective element is given from theoretical calculation. When the sample is grounded to the particle size of less than the penetration depth of all the analyte, the effect of the particle size on the intensity of the spectral line is much reduced. In the experiment, when grounded the sample to less than 8 μm(d95), the particle-size effect is much eliminated, with the correction method of theoretical α coefficient and the empirical coefficient, 14 major, minor and trace element in the carbonate can be determined accurately. And the precision of the method is much improved with RSD < 2%, except Na2O. Carbon is ultra-light element, the fluorescence yield is low and the interference is serious. With the manual multi-layer crystal PX4, coarse collimator, empirical correction, X-ray spectrometer can be used to determine the carbon dioxide in the carbonate quantitatively. The intensity of the carbon is increase with the times of the measurement and the time delay even the pellet is stored in the dessicator. So employing the latest pressed powder pellet is suggested.
Rohner, Patrick T; Blanckenhorn, Wolf U; Puniamoorthy, Nalini
2016-06-01
Sexual size dimorphism (SSD) arises when the net effects of natural and sexual selection on body size differ between the sexes. Quantitative SSD variation between taxa is common, but directional intraspecific SSD reversals are rare. We combined micro- and macroevolutionary approaches to study geographic SSD variation in closely related black scavenger flies. Common garden experiments revealed stark intra- and interspecific variation: Sepsis biflexuosa is monomorphic across the Holarctic, while S. cynipsea (only in Europe) consistently exhibits female-biased SSD. Interestingly, S. neocynipsea displays contrasting SSD in Europe (females larger) and North America (males larger), a pattern opposite to the geographic reversal in SSD of S. punctum documented in a previous study. In accordance with the differential equilibrium model for the evolution of SSD, the intensity of sexual selection on male size varied between continents (weaker in Europe), whereas fecundity selection on female body size did not. Subsequent comparative analyses of 49 taxa documented at least six independent origins of male-biased SSD in Sepsidae, which is likely caused by sexual selection on male size and mediated by bimaturism. Therefore, reversals in SSD and the associated changes in larval development might be much more common and rapid and less constrained than currently assumed. © 2016 The Author(s). Evolution © 2016 The Society for the Study of Evolution.
SIZE-SEGREGATED PARTICULATE MERCURY MEASUREMENTS IN STEUBENVILLE, OH AND DETROIT, MI, USA
This poster presents data on size-segregated particulate-phase mercury made during field intensive measurements in Steubenville, OH and Detroit, MI in 2004. The goal was to obtain information about size distribution of particle-associated mercury. A knowledge of size distributio...
Signals of vitellogenesis and estrus in female hawksbill turtles.
Kawazu, Isao; Kino, Masakatsu; Yanagisawa, Makio; Maeda, Konomi; Nakada, Ken; Yamaguchi, Yasuhiro; Sawamukai, Yutaka
2015-01-01
This study reports a viable means of identifying the vitellogenic cycle and limited estrus period in hawksbill turtles for the purposes of developing captive breeding program, based on the combination of blood metabolite parameters (triglyceride, total protein, and calcium levels), feeding status, and ovary condition. Follicle size of two focal captive females showed clear seasonal changes, with major development occurring between March and May (19.0-24.4 mm), and exceeding 25 mm between June and September. Triglyceride, total protein, and calcium levels dropped with follicular development and maintenance (March to October), and then began to rise when follicular retraction occurred from October onwards. The two focal turtles reduced food intake during intensive follicular development (April to May). These findings suggest that blood metabolite parameters and feeding conditions are inferred by the vitellogenic cycle. An additional 10 females exhibiting follicular development were mated with a single male for 7-day period between May and June. Follicle size was measured immediately prior to pairing, and a statistically significant difference in follicle size of 10 females was recorded between the seven failed (20.9 mm) and three successful (23.6 mm) mating events. This indicates follicle development is essential to successful mate and monitoring of vitellogenic cycle may help improve the success rates of captive hawksbill breeding programs.
Nosema ceranae Infection Promotes Proliferation of Yeasts in Honey Bee Intestines.
Ptaszyńska, Aneta A; Paleolog, Jerzy; Borsuk, Grzegorz
2016-01-01
Nosema ceranae infection not only damages honey bee (Apis melifera) intestines, but we believe it may also affect intestinal yeast development and its seasonal pattern. In order to check our hypothesis, infection intensity versus intestinal yeast colony forming units (CFU) both in field and cage experiments were studied. Field tests were carried out from March to October in 2014 and 2015. N. ceranae infection intensity decreased more than 100 times from 7.6 x 108 in March to 5.8 x 106 in October 2014. A similar tendency was observed in 2015. Therefore, in the European eastern limit of its range, N. ceranae infection intensity showed seasonality (spring peak and subsequent decline in the summer and fall), however, with an additional mid-summer peak that had not been recorded in other studies. Due to seasonal changes in the N. ceranae infection intensity observed in honey bee colonies, we recommend performing studies on new therapeutics during two consecutive years, including colony overwintering. A natural decrease in N. ceranae spore numbers observed from March to October might be misinterpreted as an effect of Nosema spp. treatment with new compounds. A similar seasonal pattern was observed for intestinal yeast population size in field experiments. Furthermore, cage experiments confirmed the size of intestinal yeast population to increase markedly together with the increase in the N. ceranae infection intensity. Yeast CFUs amounted to respectively 2,025 (CV = 13.04) and 11,150 (CV = 14.06) in uninfected and N. ceranae-infected workers at the end of cage experiments. Therefore, honey bee infection with N. ceranae supported additional opportunistic yeast infections, which may have resulted in faster colony depopulations.
The effect of El Chichon on the intensity and polarization of skylight at Mauna Loa
NASA Technical Reports Server (NTRS)
King, M. D.; Fraser, R. S.
1983-01-01
An empirical model of the stratospheric aerosol over Mauna Loa Observatory (MLO) has been developed, in order to study the effect of aerosol particles from the eruption of the El Chichon volcano on the intensity and degree of skylight polarization. The modeling computations were based on measurements of monthly mean optical thickness for July 1982, together with lidar measurements of the vertical distribution of aerosols. On the basis of the theoretical computations, it is shown that the number and location of polarization neutral points, and the location and magnitude of the peak polarization were both functions of the relatively narrow distribution of aerosol particle size near 0.4 microns.
Zimmerman, Guthrie S.; Sauer, John; Boomer, G. Scott; Devers, Patrick K.; Garrettson, Pamela R.
2017-01-01
The U.S. Fish and Wildlife Service (USFWS) uses data from the North American Breeding Bird Survey (BBS) to assist in monitoring and management of some migratory birds. However, BBS analyses provide indices of population change rather than estimates of population size, precluding their use in developing abundance-based objectives and limiting applicability to harvest management. Wood Ducks (Aix sponsa) are important harvested birds in the Atlantic Flyway (AF) that are difficult to detect during aerial surveys because they prefer forested habitat. We integrated Wood Duck count data from a ground-plot survey in the northeastern U.S. with AF-wide BBS, banding, parts collection, and harvest data to derive estimates of population size for the AF. Overlapping results between the smaller-scale intensive ground-plot survey and the BBS in the northeastern U.S. provided a means for scaling BBS indices to the breeding population size estimates. We applied these scaling factors to BBS results for portions of the AF lacking intensive surveys. Banding data provided estimates of annual survival and harvest rates; the latter, when combined with parts-collection data, provided estimates of recruitment. We used the harvest data to estimate fall population size. Our estimates of breeding population size and variability from the integrated population model (N̄ = 0.99 million, SD = 0.04) were similar to estimates of breeding population size based solely on data from the AF ground-plot surveys and the BBS (N̄ = 1.01 million, SD = 0.04) from 1998 to 2015. Integrating BBS data with other data provided reliable population size estimates for Wood Ducks at a scale useful for harvest and habitat management in the AF, and allowed us to derive estimates of important demographic parameters (e.g., seasonal survival rates, sex ratio) that were not directly informed by data.
Leinonen, Merja R; Raekallio, Marja R; Vainio, Outi M; Ruohoniemi, Mirja O; O'Brien, Robert T
2011-01-01
Contrast-enhanced ultrasound can be used to quantify tissue perfusion based on region of interest (ROI) analysis. The effect of the location and size of the ROI on the obtained perfusion parameters has been described in phantom, ex vivo and in vivo studies. We assessed the effects of location and size of the ROI on perfusion parameters in the renal cortex of 10 healthy, anesthetized cats using Definity contrast-enhanced ultrasound to estimate the importance of the ROI on quantification of tissue perfusion with contrast-enhanced ultrasound. Three separate sets of ROIs were placed in the renal cortex, varying in location, size or depth. There was a significant inverse association between increased depth or increased size of the ROI and peak intensity (P < 0.05). There was no statistically significant difference in the peak intensity between the ROIs placed in a row in the near field cortex. There was no significant difference in the ROIs with regard to arrival time, time to peak intensity and wash-in rate. When comparing two different ROIs in a patient with focal lesions, such as suspected neoplasia or infarction, the ROIs should always be placed at same depth and be as similar in size as possible.
NASA Astrophysics Data System (ADS)
Chen, Zi-Yu; Li, Jian-Feng; Yu, Yong; Wang, Jia-Xiang; Li, Xiao-Ya; Peng, Qi-Xian; Zhu, Wen-Jun
2012-11-01
The influences of lateral target size on hot electron production and electromagnetic pulse emission from laser interaction with metallic targets have been investigated. Particle-in-cell simulations at high laser intensities show that the yield of hot electrons tends to increase with lateral target size, because the larger surface area reduces the electrostatic field on the target, owing to its expansion along the target surface. At lower laser intensities and longer time scales, experimental data characterizing electromagnetic pulse emission as a function of lateral target size also show target-size effects. Charge separation and a larger target tending to have a lower target potential have both been observed. The increase in radiation strength and downshift in radiation frequency with increasing lateral target size can be interpreted using a simple model of the electrical capacity of the target.
Soleimani, A.; Rasta, S.H.; Banaei, T.; Asgharsharghi Bonab, A.
2017-01-01
Introduction: The aim of the present study was to determine burn intensity in retinal laser photocoagulation based on laser parameters; wavelength, power, beam size and pulse duration, using Optical Coherence Tomography (OCT), fundus camera, physical eye model and computer simulation in a clinical study. Materials and Methods: Participants were 10 adult patients between 50-80 years with proliferative diabetic retinopathy. A multicolor-photo coagulator with 532 nm green and 672 nm red for retina photocoagulation in diabetic retinopathy was used to investigate the participants. Lesion size was measured for spot sizes 50 and 100 μm, with 100 and 150 mW laser power, and pulse duration 50 and 100 ms by OCT. Artificial eye and Zemax-optical design software were used with the same laser parameters. Results: Appearance of OCT and fundus images showed direct relationship between retina burn size and lesion intensity with exposure time and power and also reverse relationship with laser spot size. Compared to red wavelength, burn size and lesion intensity increased in green wavelength. On the other hand, results from physical eye model were the same as clinical examination shown. Laser spot size in retina with Zemax simulation demonstrated that red wavelength was greater than green one. Conclusion: This study showed shorter pulses provide decrease in duration of laser surgery with significantly reduced pain. Results and calculations described in this article can help clinicians adjusting the required total coagulated area, the number of lesions and pattern density. PMID:29445713
Soleimani, A; Rasta, S H; Banaei, T; Asgharsharghi Bonab, A
2017-12-01
The aim of the present study was to determine burn intensity in retinal laser photocoagulation based on laser parameters; wavelength, power, beam size and pulse duration, using Optical Coherence Tomography (OCT), fundus camera, physical eye model and computer simulation in a clinical study. Participants were 10 adult patients between 50-80 years with proliferative diabetic retinopathy. A multicolor-photo coagulator with 532 nm green and 672 nm red for retina photocoagulation in diabetic retinopathy was used to investigate the participants. Lesion size was measured for spot sizes 50 and 100 μm, with 100 and 150 mW laser power, and pulse duration 50 and 100 ms by OCT. Artificial eye and Zemax-optical design software were used with the same laser parameters. Appearance of OCT and fundus images showed direct relationship between retina burn size and lesion intensity with exposure time and power and also reverse relationship with laser spot size. Compared to red wavelength, burn size and lesion intensity increased in green wavelength. On the other hand, results from physical eye model were the same as clinical examination shown. Laser spot size in retina with Zemax simulation demonstrated that red wavelength was greater than green one. This study showed shorter pulses provide decrease in duration of laser surgery with significantly reduced pain. Results and calculations described in this article can help clinicians adjusting the required total coagulated area, the number of lesions and pattern density.
A Millimetre-Wave Cuboid Solid Immersion Lens with Intensity-Enhanced Amplitude Mask Apodization
NASA Astrophysics Data System (ADS)
Yue, Liyang; Yan, Bing; Monks, James N.; Dhama, Rakesh; Wang, Zengbo; Minin, Oleg V.; Minin, Igor V.
2018-06-01
Photonic jet is a narrow, highly intensive, weak-diverging beam propagating into a background medium and can be produced by a cuboid solid immersion lens (SIL) in both transmission and reflection modes. Amplitude mask apodization is an optical method to further improve the spatial resolution of a SIL imaging system via reduction of waist size of photonic jet, but always leading to intensity loss due to central masking of the incoming plane wave. In this letter, we report a particularly sized millimetre-wave cuboid SIL with the intensity-enhanced amplitude mask apodization for the first time. It is able to simultaneously deliver extra intensity enhancement and waist narrowing to the produced photonic jet. Both numerical simulation and experimental verification of the intensity-enhanced apodization effect are demonstrated using a copper-masked Teflon cuboid SIL with 22-mm side length under radiation of a plane wave with 8-mm wavelength. Peak intensity enhancement and the lateral resolution of the optical system increase by about 36.0% and 36.4% in this approach, respectively.
Effects of Particle Size on the Attenuated Total Reflection Spectrum of Minerals.
Udvardi, Beatrix; Kovács, István J; Fancsik, Tamás; Kónya, Péter; Bátori, Miklósné; Stercel, Ferenc; Falus, György; Szalai, Zoltán
2017-06-01
This study focuses on particle size effect on monomineralic powders recorded using attenuated total reflection Fourier transform infrared (ATR FT-IR) spectroscopy. Six particle size fractions of quartz, feldspar, calcite, and dolomite were prepared (<2, 2-4, 4-8, 8-16, 16-32, and 32-63 µm). It is found that the width, intensity, and area of bands in the ATR FT-IR spectra of minerals have explicit dependence on the particle size. As particle size increases, the intensity and area of IR bands usually decrease while the width of bands increases. The band positions usually shifted to higher wavenumbers with decreasing particle size. Infrared spectra of minerals are the most intensive in the particle size fraction of 2-4 µm. However, if the particle size is very small (<2 µm), due to the wavelength and penetration depth of the IR light, intensity decreases. Therefore, the quantity of very fine-grained minerals may be underestimated compared to the coarser phases. A nonlinear regression analysis of the data indicated that the average coefficients and indices of the power trend line equation imply a very simplistic relationship between median particle diameter and absorbance at a given wavenumber. It is concluded that when powder samples with substantially different particle size are compared, as in regression analysis for modal predictions using ATR FT-IR, it is also important to report the grain size distribution or surface area of samples. The band area of water (3000-3620 cm -1 ) is similar in each mineral fraction, except for the particles below 2 µm. It indicates that the finest particles could have disproportionately more water adsorbed on their larger surface area. Thus, these higher wavenumbers of the ATR FT-IR spectra may be more sensitive to this spectral interference if the number of particles below 2 µm is considerable. It is also concluded that at least a proportion of the moisture could be very adhesive to the particles due to the band shift towards lower wavenumbers in the IR range of 3000-3620 cm -1 .
The Impact of Dry Midlevel Air on Hurricane Intensity in Idealized Simulations with No Mean Flow
NASA Technical Reports Server (NTRS)
Braun, Scott A.; Sippel, Jason A.; Nolan, David S.
2012-01-01
This study examines the potential negative influences of dry midlevel air on the development of tropical cyclones (specifically, its role in enhancing cold downdraft activity and suppressing storm development). The Weather Research and Forecasting model is used to construct two sets of idealized simulations of hurricane development in environments with different configurations of dry air. The first set of simulations begins with dry air located north of the vortex center by distances ranging from 0 to 270 km, whereas the second set of simulations begins with dry air completely surrounding the vortex, but with moist envelopes in the vortex core ranging in size from 0 to 150 km in radius. No impact of the dry air is seen for dry layers located more than 270 km north of the initial vortex center (approximately 3 times the initial radius of maximum wind). When the dry air is initially closer to the vortex center, it suppresses convective development where it entrains into the storm circulation, leading to increasingly asymmetric convection and slower storm development. The presence of dry air throughout the domain, including the vortex center, substantially slows storm development. However, the presence of a moist envelope around the vortex center eliminates the deleterious impact on storm intensity. Instead, storm size is significantly reduced. The simulations suggest that dry air slows intensification only when it is located very close to the vortex core at early times. When it does slow storm development, it does so primarily by inducing outward- moving convective asymmetries that temporarily shift latent heating radially outward away from the high-vorticity inner core.
Kukke, Sahana N; Paine, Rainer W; Chao, Chi-Chao; de Campos, Ana C; Hallett, Mark
2014-06-01
The purpose of this study is to develop a method to reliably characterize multiple features of the corticospinal system in a more efficient manner than typically done in transcranial magnetic stimulation studies. Forty transcranial magnetic stimulation pulses of varying intensity were given over the first dorsal interosseous motor hot spot in 10 healthy adults. The first dorsal interosseous motor-evoked potential size was recorded during rest and activation to create recruitment curves. The Boltzmann sigmoidal function was fit to the data, and parameters relating to maximal motor-evoked potential size, curve slope, and stimulus intensity leading to half-maximal motor-evoked potential size were computed from the curve fit. Good to excellent test-retest reliability was found for all corticospinal parameters at rest and during activation with 40 transcranial magnetic stimulation pulses. Through the use of curve fitting, important features of the corticospinal system can be determined with fewer stimuli than typically used for the same information. Determining the recruitment curve provides a basis to understand the state of the corticospinal system and select subject-specific parameters for transcranial magnetic stimulation testing quickly and without unnecessary exposure to magnetic stimulation. This method can be useful in individuals who have difficulty in maintaining stillness, including children and patients with motor disorders.
Tornadogensis within Hurricanes Based on the Orientation of the Rainband to the Coast after Landfall
NASA Astrophysics Data System (ADS)
Etten-Bohm, M.
2015-12-01
The focus of this study is to investigate the development of tornadoes within the rainband of a hurricane for various orientations of the rainband when a hurricane makes landfall. The rainband of a hurricane is a common area where tornadogenesis is found depending on the size, intensity, and orientation of the rain band when the storm makes landfall. As a hurricane approaches a coast line, land-surface roughness contributes to surface friction, which can contribute in tornadogenesis. The orientation of the rainband may play a part in the type of supercells that are formed in that rainband and the number and intensity of the tornadoes produced. This study will investigate if the orientation of the rainband leads to the direction in which the supercells rotate, whether clockwise or counter-clockwise, and the scale and intensity of the tornadoes produced.
Spatiotemporal Fluctuations and Triggers of Ebola Virus Spillover.
Schmidt, John Paul; Park, Andrew W; Kramer, Andrew M; Han, Barbara A; Alexander, Laura W; Drake, John M
2017-03-01
Because the natural reservoir of Ebola virus remains unclear and disease outbreaks in humans have occurred only sporadically over a large region, forecasting when and where Ebola spillovers are most likely to occur constitutes a continuing and urgent public health challenge. We developed a statistical modeling approach that associates 37 human or great ape Ebola spillovers since 1982 with spatiotemporally dynamic covariates including vegetative cover, human population size, and absolute and relative rainfall over 3 decades across sub-Saharan Africa. Our model (area under the curve 0.80 on test data) shows that spillover intensity is highest during transitions between wet and dry seasons; overall, high seasonal intensity occurs over much of tropical Africa; and spillover intensity is greatest at high (>1,000/km 2 ) and very low (<100/km 2 ) human population densities compared with intermediate levels. These results suggest strong seasonality in Ebola spillover from wild reservoirs and indicate particular times and regions for targeted surveillance.
Mao, Chen-Chen; Zhou, Xing-Yu; Zhu, Jian-Rong; Zhang, Chun-Hui; Zhang, Chun-Mei; Wang, Qin
2018-05-14
Recently Zhang et al [ Phys. Rev. A95, 012333 (2017)] developed a new approach to estimate the failure probability for the decoy-state BB84 QKD system when taking finite-size key effect into account, which offers security comparable to Chernoff bound, while results in an improved key rate and transmission distance. Based on Zhang et al's work, now we extend this approach to the case of the measurement-device-independent quantum key distribution (MDI-QKD), and for the first time implement it onto the four-intensity decoy-state MDI-QKD system. Moreover, through utilizing joint constraints and collective error-estimation techniques, we can obviously increase the performance of practical MDI-QKD systems compared with either three- or four-intensity decoy-state MDI-QKD using Chernoff bound analysis, and achieve much higher level security compared with those applying Gaussian approximation analysis.
NASA Astrophysics Data System (ADS)
Huang, Haijun; Shu, Da; Fu, Yanan; Zhu, Guoliang; Wang, Donghong; Dong, Anping; Sun, Baode
2018-06-01
The size of cavitation region is a key parameter to estimate the metallurgical effect of ultrasonic melt treatment (UST) on preferential structure refinement. We present a simple numerical model to predict the characteristic length of the cavitation region, termed cavitation depth, in a metal melt. The model is based on wave propagation with acoustic attenuation caused by cavitation bubbles which are dependent on bubble characteristics and ultrasonic intensity. In situ synchrotron X-ray imaging of cavitation bubbles has been made to quantitatively measure the size of cavitation region and volume fraction and size distribution of cavitation bubbles in an Al-Cu melt. The results show that cavitation bubbles maintain a log-normal size distribution, and the volume fraction of cavitation bubbles obeys a tanh function with the applied ultrasonic intensity. Using the experimental values of bubble characteristics as input, the predicted cavitation depth agrees well with observations except for a slight deviation at higher acoustic intensities. Further analysis shows that the increase of bubble volume and bubble size both leads to higher attenuation by cavitation bubbles, and hence, smaller cavitation depth. The current model offers a guideline to implement UST, especially for structural refinement.
NASA Astrophysics Data System (ADS)
Huang, Haijun; Shu, Da; Fu, Yanan; Zhu, Guoliang; Wang, Donghong; Dong, Anping; Sun, Baode
2018-04-01
The size of cavitation region is a key parameter to estimate the metallurgical effect of ultrasonic melt treatment (UST) on preferential structure refinement. We present a simple numerical model to predict the characteristic length of the cavitation region, termed cavitation depth, in a metal melt. The model is based on wave propagation with acoustic attenuation caused by cavitation bubbles which are dependent on bubble characteristics and ultrasonic intensity. In situ synchrotron X-ray imaging of cavitation bubbles has been made to quantitatively measure the size of cavitation region and volume fraction and size distribution of cavitation bubbles in an Al-Cu melt. The results show that cavitation bubbles maintain a log-normal size distribution, and the volume fraction of cavitation bubbles obeys a tanh function with the applied ultrasonic intensity. Using the experimental values of bubble characteristics as input, the predicted cavitation depth agrees well with observations except for a slight deviation at higher acoustic intensities. Further analysis shows that the increase of bubble volume and bubble size both leads to higher attenuation by cavitation bubbles, and hence, smaller cavitation depth. The current model offers a guideline to implement UST, especially for structural refinement.
Nathaniel M. Anderson; Rene H. Germain; Myrna H. Hall
2012-01-01
Between 1984 and 2000, the parcelization of family forests in the New York City Watershed caused a decline in average parcel size from 19 to 16 ac. However, little is known about the timing and intensity of development on subdivided parcels, which has the potential to negatively affect water quality by increasing nonpoint source pollution associated with nutrient...
Spatial Analysis of Great Lakes Regional Icing Cloud Liquid Water Content
NASA Technical Reports Server (NTRS)
Ryerson, Charles C.; Koenig, George G.; Melloh, Rae A.; Meese, Debra A.; Reehorst, Andrew L.; Miller, Dean R.
2003-01-01
Abstract Clustering of cloud microphysical conditions, such as liquid water content (LWC) and drop size, can affect the rate and shape of ice accretion and the airworthiness of aircraft. Clustering may also degrade the accuracy of cloud LWC measurements from radars and microwave radiometers being developed by the government for remotely mapping icing conditions ahead of aircraft in flight. This paper evaluates spatial clustering of LWC in icing clouds using measurements collected during NASA research flights in the Great Lakes region. We used graphical and analytical approaches to describe clustering. The analytical approach involves determining the average size of clusters and computing a clustering intensity parameter. We analyzed flight data composed of 1-s-frequency LWC measurements for 12 periods ranging from 17.4 minutes (73 km) to 45.3 minutes (190 km) in duration. Graphically some flight segments showed evidence of consistency with regard to clustering patterns. Cluster intensity varied from 0.06, indicating little clustering, to a high of 2.42. Cluster lengths ranged from 0.1 minutes (0.6 km) to 4.1 minutes (17.3 km). Additional analyses will allow us to determine if clustering climatologies can be developed to characterize cluster conditions by region, time period, or weather condition. Introduction
NASA Astrophysics Data System (ADS)
Samkoe, Kimberley S.; Bates, Brent D.; Tselepidakis, Niki N.; DSouza, Alisha V.; Gunn, Jason R.; Ramkumar, Dipak B.; Paulsen, Keith D.; Pogue, Brian W.; Henderson, Eric R.
2017-12-01
Wide local excision (WLE) of tumors with negative margins remains a challenge because surgeons cannot directly visualize the mass. Fluorescence-guided surgery (FGS) may improve surgical accuracy; however, conventional methods with direct surface tumor visualization are not immediately applicable, and properties of tissues surrounding the cancer must be considered. We developed a phantom model for sarcoma resection with the near-infrared fluorophore IRDye 800CW and used it to iteratively define the properties of connective tissues that typically surround sarcoma tumors. We then tested the ability of a blinded surgeon to resect fluorescent tumor-simulating inclusions with ˜1-cm margins using predetermined target fluorescence intensities and a Solaris open-air fluorescence imaging system. In connective tissue-simulating phantoms, fluorescence intensity decreased with increasing blood concentration and increased with increasing intralipid concentrations. Fluorescent inclusions could be resolved at ≥1-cm depth in all inclusion concentrations and sizes tested. When inclusion depth was held constant, fluorescence intensity decreased with decreasing volume. Using targeted fluorescence intensities, a blinded surgeon was able to successfully excise inclusions with ˜1-cm margins from fat- and muscle-simulating phantoms with inclusion-to-background contrast ratios as low as 2∶1. Indirect, subsurface FGS is a promising tool for surgical resection of cancers requiring WLE.
Age-Related Differences in Muscle Fatigue Vary by Contraction Type: A Meta-analysis
Avin, Keith G.
2011-01-01
Background During senescence, despite the loss of strength (force-generating capability) associated with sarcopenia, muscle endurance may improve for isometric contractions. Purpose The purpose of this study was to perform a systematic meta-analysis of young versus older adults, considering likely moderators (ie, contraction type, joint, sex, activity level, and task intensity). Data Sources A 2-stage systematic review identified potential studies from PubMed, CINAHL, PEDro, EBSCOhost: ERIC, EBSCOhost: Sportdiscus, and The Cochrane Library. Study Selection Studies reporting fatigue tasks (voluntary activation) performed at a relative intensity in both young (18–45 years of age) and old (≥55 years of age) adults who were healthy were considered. Data Extraction Sample size, mean and variance outcome data (ie, fatigue index or endurance time), joint, contraction type, task intensity (percentage of maximum), sex, and activity levels were extracted. Data Synthesis Effect sizes were (1) computed for all data points; (2) subgrouped by contraction type, sex, joint or muscle group, intensity, or activity level; and (3) further subgrouped between contraction type and the remaining moderators. Out of 3,457 potential studies, 46 publications (with 78 distinct effect size data points) met all inclusion criteria. Limitations A lack of available data limited subgroup analyses (ie, sex, intensity, joint), as did a disproportionate spread of data (most intensities ≥50% of maximum voluntary contraction). Conclusions Overall, older adults were able to sustain relative-intensity tasks significantly longer or with less force decay than younger adults (effect size=0.49). However, this age-related difference was present only for sustained and intermittent isometric contractions, whereas this age-related advantage was lost for dynamic tasks. When controlling for contraction type, the additional modifiers played minor roles. Identifying muscle endurance capabilities in the older adult may provide an avenue to improve functional capabilities, despite a clearly established decrement in peak torque. PMID:21616932
Evaluation of intrinsic respiratory signal determination methods for 4D CBCT adapted for mice
DOE Office of Scientific and Technical Information (OSTI.GOV)
Martin, Rachael; Pan, Tinsu, E-mail: tpan@mdanderson.org; Rubinstein, Ashley
Purpose: 4D CT imaging in mice is important in a variety of areas including studies of lung function and tumor motion. A necessary step in 4D imaging is obtaining a respiratory signal, which can be done through an external system or intrinsically through the projection images. A number of methods have been developed that can successfully determine the respiratory signal from cone-beam projection images of humans, however only a few have been utilized in a preclinical setting and most of these rely on step-and-shoot style imaging. The purpose of this work is to assess and make adaptions of several successfulmore » methods developed for humans for an image-guided preclinical radiation therapy system. Methods: Respiratory signals were determined from the projection images of free-breathing mice scanned on the X-RAD system using four methods: the so-called Amsterdam shroud method, a method based on the phase of the Fourier transform, a pixel intensity method, and a center of mass method. The Amsterdam shroud method was modified so the sharp inspiration peaks associated with anesthetized mouse breathing could be detected. Respiratory signals were used to sort projections into phase bins and 4D images were reconstructed. Error and standard deviation in the assignment of phase bins for the four methods compared to a manual method considered to be ground truth were calculated for a range of region of interest (ROI) sizes. Qualitative comparisons were additionally made between the 4D images obtained using each of the methods and the manual method. Results: 4D images were successfully created for all mice with each of the respiratory signal extraction methods. Only minimal qualitative differences were noted between each of the methods and the manual method. The average error (and standard deviation) in phase bin assignment was 0.24 ± 0.08 (0.49 ± 0.11) phase bins for the Fourier transform method, 0.09 ± 0.03 (0.31 ± 0.08) phase bins for the modified Amsterdam shroud method, 0.09 ± 0.02 (0.33 ± 0.07) phase bins for the intensity method, and 0.37 ± 0.10 (0.57 ± 0.08) phase bins for the center of mass method. Little dependence on ROI size was noted for the modified Amsterdam shroud and intensity methods while the Fourier transform and center of mass methods showed a noticeable dependence on the ROI size. Conclusions: The modified Amsterdam shroud, Fourier transform, and intensity respiratory signal methods are sufficiently accurate to be used for 4D imaging on the X-RAD system and show improvement over the existing center of mass method. The intensity and modified Amsterdam shroud methods are recommended due to their high accuracy and low dependence on ROI size.« less
An empirical investigation of theoretical loss and gambling intensity.
Auer, Michael; Griffiths, Mark D
2014-12-01
Many recent studies of internet gambling-particularly those that have analysed behavioural tracking data-have used variables such 'bet size' and 'number of games played' as proxy measures for 'gambling intensity'. In this paper it is argued that the most stable and reliable measure for 'gambling intensity' is the 'theoretical loss' (a product of total bet size and house advantage). In the long run, the theoretical loss corresponds with the Gross Gaming Revenue generated by commercial gaming operators. For shorter periods of time, theoretical loss is the most stable measure of gambling intensity as it is not distorted by gamblers' occasional wins. Even for single bets, the theoretical loss reflects the amount a player is willing to risk. Using behavioural tracking data of 100,000 players who played online casino, lottery and/or poker games, this paper also demonstrates that bet size does not equate to or explain theoretical loss as it does not take into account the house advantage. This lack of accuracy is shown to be even more pronounced for gamblers who play a variety of games.
Granton, Patrick V; Verhaegen, Frank
2013-05-21
Precision image-guided small animal radiotherapy is rapidly advancing through the use of dedicated micro-irradiation devices. However, precise modeling of these devices in model-based dose-calculation algorithms such as Monte Carlo (MC) simulations continue to present challenges due to a combination of very small beams, low mechanical tolerances on beam collimation, positioning and long calculation times. The specific intent of this investigation is to introduce and demonstrate the viability of a fast analytical source model (AM) for use in either investigating improvements in collimator design or for use in faster dose calculations. MC models using BEAMnrc were developed for circular and square fields sizes from 1 to 25 mm in diameter (or side) that incorporated the intensity distribution of the focal spot modeled after an experimental pinhole image. These MC models were used to generate phase space files (PSFMC) at the exit of the collimators. An AM was developed that included the intensity distribution of the focal spot, a pre-calculated x-ray spectrum, and the collimator-specific entrance and exit apertures. The AM was used to generate photon fluence intensity distributions (ΦAM) and PSFAM containing photons radiating at angles according to the focal spot intensity distribution. MC dose calculations using DOSXYZnrc in a water and mouse phantom differing only by source used (PSFMC versus PSFAM) were found to agree within 7% and 4% for the smallest 1 and 2 mm collimator, respectively, and within 1% for all other field sizes based on depth dose profiles. PSF generation times were approximately 1200 times faster for the smallest beam and 19 times faster for the largest beam. The influence of the focal spot intensity distribution on output and on beam shape was quantified and found to play a significant role in calculated dose distributions. Beam profile differences due to collimator alignment were found in both small and large collimators sensitive to shifts of 1 mm with respect to the central axis.
Sizing gaseous emboli using Doppler embolic signal intensity.
Banahan, Caroline; Hague, James P; Evans, David H; Patel, Rizwan; Ramnarine, Kumar V; Chung, Emma M L
2012-05-01
Extension of transcranial Doppler embolus detection to estimation of bubble size has historically been hindered by difficulties in applying scattering theory to the interpretation of clinical data. This article presents a simplified approach to the sizing of air emboli based on analysis of Doppler embolic signal intensity, by using an approximation to the full scattering theory that can be solved to estimate embolus size. Tests using simulated emboli show that our algorithm is theoretically capable of sizing 90% of "emboli" to within 10% of their true radius. In vitro tests show that 69% of emboli can be sized to within 20% of their true value under ideal conditions, which reduces to 30% of emboli if the beam and vessel are severely misaligned. Our results demonstrate that estimation of bubble size during clinical monitoring could be used to distinguish benign microbubbles from potentially harmful macrobubbles during intraoperative clinical monitoring. Copyright © 2012 World Federation for Ultrasound in Medicine & Biology. Published by Elsevier Inc. All rights reserved.
NASA Astrophysics Data System (ADS)
Esmaili, Rebekah Bradley
Global climate models, numerical weather prediction, and flood models rely on accurate satellite precipitation products, which are the only datasets that are continuous in time and space across the globe. While there are more earth observing satellites than ever before, gaps in precipitation retrievals exist due to sensor and orbital limitations of low-earth (LEO) satellites, which are overcome by merging data from different sensors in satellite precipitation products (SPPs). Using cloud tracking at higher resolutions than the spatio-temporal scales of LEO satellites, this thesis examines how clouds typically form in the atmosphere, the rate that cloud size and temperature evolve over the life cycle, and the time of day that cloud development take place. This thesis found that cloud evolution was non-linear, which disagrees with the linear interpolation schemes used in SPPs. Longer lasting clouds tended to achieve their temperature and size maturity milestones at different times, while these stages often occurred simultaneously in shorter lasting clouds. Over the ocean, longer lasting clouds were found to occur more frequently at night, while shorter lasting clouds were more common during the daytime. This thesis also examines whether large-scale Saharan dust outbreaks can impact the trajectories and intensity of cloud clusters in the tropical Atlantic, which is predicted by modeling studies. The presented results show that proximity to Saharan dust outbreaks shifts Atlantic cloud development northward and intense storms becoming more common, whereas on days with low dust loading small-scale, warmer clouds are more common. A simplified view of cloud evolution in merged rainfall retrievals is a possible source of errors, which can propagate into higher level analysis. This thesis investigates the difference in the intensity, duration, and frequency of precipitation in IMERG, a next-generation satellite precipitation product with ground radar observations over the contiguous United States. There was agreement on seasonal totals, but closer examination shows that the average intensity and duration of events is too high, and too infrequent compared to events detected on the ground. Awareness of the strengths and limitations, particularly in context of high-resolution cloud development, can enhance SPPs and can complement climate model simulations.
The Italian contribution to battery science and technology
NASA Astrophysics Data System (ADS)
Scrosati, Bruno
The activities in the battery field currently in progress in Italian academic and industrial laboratories will be briefly reviewed. After reporting the key achievements obtained in lead-acid batteries, the presentation will be focused on systems of more recent development with particular attention to the lithium batteries. Interestingly, there is in Italy quite an intense research and development activity on these new-concept batteries which are now the power sources of choice for popular electronic devices, e.g. cellular phones, and in prospect valid systems for powering electric vehicles. Basic research is carried out in various university and government centers with the aim of characterizing new lithium ion electrode and electrolyte materials. This intense research is backed by substantial development activity since few Italian industries are presently engaged in the production of lithium batteries of different size and characteristics. Italy is then well established in battery R&D, confirming the country's historical involvement in the field since Volta's pile invention in 1800.
The HMDS Coating Flaw Removal Tool
DOE Office of Scientific and Technical Information (OSTI.GOV)
Monticelli, M V; Nostrand, M C; Mehta, N
2008-10-24
In many high energy laser systems, optics with HMDS sol gel antireflective coatings are placed in close proximity to each other making them particularly susceptible to certain types of strong optical interactions. During the coating process, halo shaped coating flaws develop around surface digs and particles. Depending on the shape and size of the flaw, the extent of laser light intensity modulation and consequent probability of damaging downstream optics may increase significantly. To prevent these defects from causing damage, a coating flaw removal tool was developed that deploys a spot of decane with a syringe and dissolves away the coatingmore » flaw. The residual liquid is evacuated leaving an uncoated circular spot approximately 1mm in diameter. The resulting uncoated region causes little light intensity modulation and thus has a low probability of causing damage in optics downstream from the mitigated flaw site.« less
Breulmann, Marc; Masyutenko, Nina Petrovna; Kogut, Boris Maratovich; Schroll, Reiner; Dörfler, Ulrike; Buscot, François; Schulz, Elke
2014-11-01
The quality, stability and availability of organic carbon (OC) in soil organic matter (SOM) can vary widely between differently managed ecosystems. Several approaches have been developed for isolating SOM fractions to examine their ecological roles, but links between the bioavailability of the OC of size-density fractions and soil microbial communities have not been previously explored. Thus, in the presented laboratory study we investigated the potential bioavailability of OC and the structure of associated microbial communities in different particle-size and density fractions of SOM. For this we used samples from four grassland ecosystems with contrasting management intensity regimes and two soil types: a Haplic Cambisol and a typical Chernozem. A combined size-density fractionation protocol was applied to separate clay-associated SOM fractions (CF1, <1 μm; CF2, 1-2 μm) from light SOM fractions (LF1, <1.8 g cm(-3); LF2, 1.8-2.0 g cm(-3)). These fractions were used as carbon sources in a respiration experiment to determine their potential bioavailability. Measured CO2-release was used as an index of substrate accessibility and linked to the soil microbial community structure, as determined by phospholipid fatty acids (PLFA) analysis. Several key factors controlling decomposition processes, and thus the potential bioavailability of OC, were identified: management intensity and the plant community composition of the grasslands (both of which affect the chemical composition and turnover of OC) and specific properties of individual SOM fractions. The PLFA patterns highlighted differences in the composition of microbial communities associated with the examined grasslands, and SOM fractions, providing the first broad insights into their active microbial communities. From observed interactions between abiotic and biotic factors affecting the decomposition of SOM fractions we demonstrate that increasing management intensity could enhance the potential bioavailability of OC, not only in the active and intermediate SOM pools, but also in the passive pool. Copyright © 2014 Elsevier B.V. All rights reserved.
A novel fluorescent retrograde neural tracer: cholera toxin B conjugated carbon dots
NASA Astrophysics Data System (ADS)
Zhou, Nan; Hao, Zeyu; Zhao, Xiaohuan; Maharjan, Suraj; Zhu, Shoujun; Song, Yubin; Yang, Bai; Lu, Laijin
2015-09-01
The retrograde neuroanatomical tracing method is a key technique to study the complex interconnections of the nervous system. Traditional tracers have several drawbacks, including time-consuming immunohistochemical or immunofluorescent staining procedures, rapid fluorescence quenching and low fluorescence intensity. Carbon dots (CDs) have been widely used as a fluorescent bio-probe due to their ultrasmall size, excellent optical properties, chemical stability, biocompatibility and low toxicity. Herein, we develop a novel fluorescent neural tracer: cholera toxin B-carbon dot conjugates (CTB-CDs). It can be taken up and retrogradely transported by neurons in the peripheral nervous system of rats. Our results show that CTB-CDs possess high photoluminescence intensity, good optical stability, a long shelf-life and non-toxicity. Tracing with CTB-CDs is a direct and more economical way of performing retrograde labelling experiments. Therefore, CTB-CDs are reliable fluorescent retrograde tracers.The retrograde neuroanatomical tracing method is a key technique to study the complex interconnections of the nervous system. Traditional tracers have several drawbacks, including time-consuming immunohistochemical or immunofluorescent staining procedures, rapid fluorescence quenching and low fluorescence intensity. Carbon dots (CDs) have been widely used as a fluorescent bio-probe due to their ultrasmall size, excellent optical properties, chemical stability, biocompatibility and low toxicity. Herein, we develop a novel fluorescent neural tracer: cholera toxin B-carbon dot conjugates (CTB-CDs). It can be taken up and retrogradely transported by neurons in the peripheral nervous system of rats. Our results show that CTB-CDs possess high photoluminescence intensity, good optical stability, a long shelf-life and non-toxicity. Tracing with CTB-CDs is a direct and more economical way of performing retrograde labelling experiments. Therefore, CTB-CDs are reliable fluorescent retrograde tracers. Electronic supplementary information (ESI) available: PL spectra of CTB; absorption spectra of dialysate; fluorescence signal and immunohistochemical staining of CTB-CDs in L4 DRG. See DOI: 10.1039/c5nr04361a
Light-intensity modulator withstands high heat fluxes
NASA Technical Reports Server (NTRS)
Maples, H. G.; Strass, H. K.
1966-01-01
Mechanism modulates and controls the intensity of luminous radiation in light beams associated with high-intensity heat flux. This modulator incorporates two fluid-cooled, externally grooved, contracting metal cylinders which when rotated about their longitudinal axes present a circular aperture of varying size depending on the degree of rotation.
NASA Astrophysics Data System (ADS)
de Winter, W.; van Dam, D. B.; Delbecque, N.; Verdoodt, A.; Ruessink, B. G.; Sterk, G.
2018-04-01
The commonly observed over prediction of aeolian saltation transport on sandy beaches is, at least in part, caused by saltation intermittency. To study small-scale saltation processes, high frequency saltation sensors are required on a high spatial resolution. Therefore, we developed a low-cost Saltation Detection System (SalDecS) with the aim to measure saltation intensity at a frequency of 10 Hz and with a spatial resolution of 0.10 m in wind-normal direction. Linearity and equal sensitivity of the saltation sensors were investigated during wind tunnel and field experiments. Wind tunnel experiments with a set of 7 SalDec sensors revealed that the variability of sensor sensitivity is at maximum 9% during relatively low saltation intensities. During more intense saltation the variability of sensor sensitivity decreases. A sigmoidal fit describes the relation between mass flux and sensor output measured during 5 different wind conditions. This indicates an increasing importance of sensor saturation with increasing mass flux. We developed a theoretical model to simulate and describe the effect of grain size, grain velocity and saltation intensity on sensor saturation. Time-averaged field measurements revealed sensitivity equality for 85 out of a set of 89 horizontally deployed SalDec sensors. On these larger timescales (hours) saltation variability imposed by morphological features, such as sand strips, can be recognized. We conclude that the SalDecS can be used to measure small-scale spatiotemporal variabilities of saltation intensity to investigate saltation characteristics related to wind turbulence.
Ultrasonic synthesis of hydroxyapatite in non-cavitation and cavitation modes.
Nikolaev, A L; Gopin, A V; Severin, A V; Rudin, V N; Mironov, M A; Dezhkunov, N V
2018-06-01
The size control of materials is of great importance in research and technology because materials of different size and shape have different properties and applications. This paper focuses on the synthesis of hydroxyapatite in ultrasound fields of different frequencies and intensities with the aim to find the conditions which allow control of the particles size. The results are evaluated by X-ray diffraction, Transmission Electron Microscopy, morphological and sedimentation analyses. It is shown that the hydroxyapatite particles synthesized at low intensity non-cavitation regime of ultrasound have smaller size than those prepared at high intensity cavitation regime. The explanation of observed results is based on the idea of formation of vortices at the interface between phosphoric acid and calcium hydroxide solution where the nucleation of hydroxyapatite particles is taken place. Smaller vortices formed at high frequency non-cavitation ultrasound regime provide smaller nucleation sites and smaller resulting particles, compared to vortices and particles obtained without ultrasound. Discovered method has a potential of industrial application of ultrasound for the controlled synthesis of nanoparticles. Copyright © 2018 Elsevier B.V. All rights reserved.
Bubble performance of a novel dissolved air flotation(DAF) unit.
Chen, Fu-tai; Peng, Feng-xian; Wu, Xiao-qing; Luan, Zhao-kun
2004-01-01
ES-DAF, a novel DAF with low cost, high reliability and easy controllability, was studied. Without a costly air saturator, ES-DAF consists of an ejector and a static mixer between the pressure side and suction side of the recycle rotary pump. The bubble size distribution in this novel unit was studied in detail by using a newly developed CCD imagination through a microscope. Compared with M-DAF under the same saturation pressure, ES-DAF can produce smaller bubble size and higher bubble volume concentration, especially in lower pressure. In addition, the bubble size decreases with the increase of reflux ratio or decrease of superficial air-water ratio. These results suggested that smaller bubbles will be formed when the initial number of nucleation sites increases by enhancing the turbulence intensity in the saturation system.
NASA Astrophysics Data System (ADS)
Rykov, A. I.; Nomura, K.; Wang, J.
2013-08-01
We report on recent developments in the analysis of nuclear forward scattering (NFS) using the Fourier transformation of measured time spectra. In the frequency domain, it is shown that the lineshape is generally described by the convolution of two intensity factors. One of them is Lorentzian related to free decay. We derived the expressions for the second factor related to the Frenkel exciton polariton formed in Mössbauer media. For stray particles of a powder spread over a 2D surface the particle size distribution can be derived from Mössbauer thickness distribution. The thickness-related lineshape is deconvolved through sharpening the Fourier NFS spectra. The lineshapes in these sharpened spectra are theoretically expressed via the parameters of the particle size distributions. Through fitting the lineshapes with our theoretical expressions the particle size distribution parameters were determined.
Comparative measurements using different particle size instruments
NASA Technical Reports Server (NTRS)
Chigier, N.
1984-01-01
This paper discusses the measurement and comparison of particle size and velocity measurements in sprays. The general nature of sprays and the development of standard, consistent research sprays are described. The instruments considered in this paper are: pulsed laser photography, holography, television, and cinematography; laser anemometry and interferometry using visibility, peak amplitude, and intensity ratioing; and laser diffraction. Calibration is by graticule, reticle, powders with known size distributions in liquid cells, monosize sprays, and, eventually, standard sprays. Statistical analyses including spatial and temporal long-time averaging as well as high-frequency response time histories with conditional sampling are examined. Previous attempts at comparing instruments, the making of simultaneous or consecutive measurements with similar types and different types of imaging, interferometric, and diffraction instruments are reviewed. A program of calibration and experiments for comparing and assessing different instruments is presented.
NASA Technical Reports Server (NTRS)
Deguchi, Shuji; Watson, William D.
1988-01-01
Statistical methods are developed for gravitational lensing in order to obtain analytic expressions for the average surface brightness that include the effects of microlensing by stellar (or other compact) masses within the lensing galaxy. The primary advance here is in utilizing a Markoff technique to obtain expressions that are valid for sources of finite size when the surface density of mass in the lensing galaxy is large. The finite size of the source is probably the key consideration for the occurrence of microlensing by individual stars. For the intensity from a particular location, the parameter which governs the importance of microlensing is determined. Statistical methods are also formulated to assess the time variation of the surface brightness due to the random motion of the masses that cause the microlensing.
The Relation Between Dry Vortex Merger and Tropical Cyclone Genesis over the Atlantic Ocean
DOE Office of Scientific and Technical Information (OSTI.GOV)
Chen, Shu-Hua; Liu, Yi-Chin
2014-10-27
A strong, convective African tropical disturbance has a greater chance to develop into a Tropical 23 Depression (TD) if it merges with a shallow, dry vortex (D-vortex) from the north of the African 24 easterly jet (AEJ) after leaving the western coast. Using 11-year reanalysis data we found that the 25 western tip of a vortex strip at northwestern Africa can serve as dry vortices for the D-vortex 26 merger if it shifts southward. Another source of D-vortices is the westward propagating lows 27 along the southern edge of the Saharan air. The D-vortex merger process occurred for 63.5% ofmore » 28 tropical cyclones (TCs) or developing systems over the main development region of the Atlantic 29 Ocean, while it occurred for 54% of non-developing systems. TC genesis could be largely 30 controlled by the large-scale environment, but the differences in characteristics of vortices 31 associated with the D-vortex merger between developing and non-developing systems could 32 potentially help determine their destinies; in general, developing systems were dominated by a 33 more intense and moist south vortex, while non-developing systems were dominated by a north 34 vortex which was more intense, drier, and larger in size. Analysis also shows that 74% of intense 35 developing systems were involved with the D-vortex merger process. More attention needs to be 36 paid to the D-vortex merger and the characteristics of those vortices as they can play significant 37 roles or have a strong indication in Atlantic TC genesis.« less
Electrochemical Migration of Fine-Pitch Nanopaste Ag Interconnects
NASA Astrophysics Data System (ADS)
Tsou, Chia-Hung; Liu, Kai-Ning; Lin, Heng-Tien; Ouyang, Fan-Yi
2016-12-01
With the development of intelligent electronic products, usage of fine-pitch interconnects has become mainstream in high performance electronic devices. Electrochemical migration (ECM) of interconnects would be a serious reliability problem under temperature, humidity and biased voltage environments. In this study, ECM behavior of nanopaste Ag interconnects with pitch size from 20 μm to 50 μm was evaluated by thermal humidity bias (THB) and water drop (WD) tests with deionized water through in situ leakage current-versus-time (CVT) curve. The results indicate that the failure time of ECM in fine-pitch samples occurs within few seconds under WD testing and it increases with increasing pitch size. The microstructure examination indicated that intensive dendrite formation of Ag through the whole interface was found to bridge the two electrodes. In the THB test, the CVT curve exhibited two stages, incubation and ramp-up; failure time of ECM was about 173.7 min. In addition, intensive dendrite formation was observed only at the protrusion of the Ag interconnects due to the concentration of the electric field at the protrusion of the Ag interconnects.
Physical pretreatment – woody biomass size reduction – for forest biorefinery
J.Y. Zhu
2011-01-01
Physical pretreatment of woody biomass or wood size reduction is a prerequisite step for further chemical or biochemical processing in forest biorefinery. However, wood size reduction is very energy intensive which differentiates woody biomass from herbaceous biomass for biorefinery. This chapter discusses several critical issues related to wood size reduction: (1)...
Beyond eruptive scenarios: assessing tephra fallout hazard from Neapolitan volcanoes.
Sandri, Laura; Costa, Antonio; Selva, Jacopo; Tonini, Roberto; Macedonio, Giovanni; Folch, Arnau; Sulpizio, Roberto
2016-04-12
Assessment of volcanic hazards is necessary for risk mitigation. Typically, hazard assessment is based on one or a few, subjectively chosen representative eruptive scenarios, which use a specific combination of eruptive sizes and intensities to represent a particular size class of eruption. While such eruptive scenarios use a range of representative members to capture a range of eruptive sizes and intensities in order to reflect a wider size class, a scenario approach neglects to account for the intrinsic variability of volcanic eruptions, and implicitly assumes that inter-class size variability (i.e. size difference between different eruptive size classes) dominates over intra-class size variability (i.e. size difference within an eruptive size class), the latter of which is treated as negligible. So far, no quantitative study has been undertaken to verify such an assumption. Here, we adopt a novel Probabilistic Volcanic Hazard Analysis (PVHA) strategy, which accounts for intrinsic eruptive variabilities, to quantify the tephra fallout hazard in the Campania area. We compare the results of the new probabilistic approach with the classical scenario approach. The results allow for determining whether a simplified scenario approach can be considered valid, and for quantifying the bias which arises when full variability is not accounted for.
Zhang, Lai; Andersen, Ken H; Dieckmann, Ulf; Brännström, Åke
2015-09-07
We investigate how four types of interference competition - which alternatively affect foraging, metabolism, survival, and reproduction - impact the ecology and evolution of size-structured populations. Even though all four types of interference competition reduce population biomass, interference competition at intermediate intensity sometimes significantly increases the abundance of adult individuals and the population׳s reproduction rate. We find that foraging and metabolic interference evolutionarily favor smaller maturation size when interference is weak and larger maturation size when interference is strong. The evolutionary response to survival interference and reproductive interference is always larger maturation size. We also investigate how the four types of interference competition impact the evolutionary dynamics and resultant diversity and trophic structure of size-structured communities. Like other types of trait-mediated competition, all four types of interference competition can induce disruptive selection and thus promote initial diversification. Even though foraging interference and reproductive interference are more potent in promoting initial diversification, they catalyze the formation of diverse communities with complex trophic structure only at high levels of interference intensity. By contrast, survival interference does so already at intermediate levels, while reproductive interference can only support relatively smaller communities with simpler trophic structure. Taken together, our results show how the type and intensity of interference competition jointly affect coexistence patterns in structured population models. Copyright © 2015 Elsevier Ltd. All rights reserved.
Yuan, Baohong; Pei, Yanbo; Kandukuri, Jayanth
2013-01-01
Our recently developed ultrasound-switchable fluorescence (USF) imaging technique showed that it was feasible to conduct high-resolution fluorescence imaging in a centimeter-deep turbid medium. Because the spatial resolution of this technique highly depends on the ultrasound-induced temperature focal size (UTFS), minimization of UTFS becomes important for further improving the spatial resolution USF technique. In this study, we found that UTFS can be significantly reduced below the diffraction-limited acoustic intensity focal size via nonlinear acoustic effects and thermal confinement by appropriately controlling ultrasound power and exposure time, which can be potentially used for deep-tissue high-resolution imaging. PMID:23479498
NASA Astrophysics Data System (ADS)
Sarmiento, G.; Sanz, S.; Pujana, A.; Merino, J. M.; Iturbe, R.; Apiñaniz, S.; Nardelli, D.; Marino, I.
2014-05-01
Although renewable sector has started to take advantage of the offshore wind energy recently, the development is very intense. Turbines reliability, size, and cost are key aspects for the wind industry, especially in marine locations. A superconducting generator will allow a significant reduction in terms of weight and size, but cost and reliability are two aspects to deal with. MgB2 wire is presented as one promising option to be used in superconducting coils for wind generators. This work shows the experimental results in first cryogen-free MgB2 prototype coils, designed according to specific requirements of TECNALIA's wind generator concept.
Optimizing the selection of small-town wastewater treatment processes
NASA Astrophysics Data System (ADS)
Huang, Jianping; Zhang, Siqi
2018-04-01
Municipal wastewater treatment is energy-intensive. This high energy consumption causes high sewage treatment plant operating costs and increases the energy burden. To mitigate the adverse impacts of China’s development, sewage treatment plants should adopt effective energy-saving technologies. Artificial fortified natural water treatment and use of activated sludge and biofilm are all suitable technologies for small-town sewage treatment. This study features an analysis of the characteristics of small and medium-sized township sewage, an overview of current technologies, and a discussion of recent progress in sewage treatment. Based on this, an analysis of existing problems in municipal wastewater treatment is presented, and countermeasures to improve sewage treatment in small and medium-sized towns are proposed.
Comparison of absolute intensity between EAS with gamma-families and general EAS at Mount Norikura
NASA Technical Reports Server (NTRS)
Mitsumune, T.; Nakatsuka, T.; Nishikawa, K.; Saito, T.; Sakata, M.; Shima, M.; Yamamoto, Y.; Dake, S.; Kawamoto, M.; Kusumose, M.
1985-01-01
Gamma-families with total energy greater than 10 TeV, found in the EX chamber which was cooperated with the EAS array were combined with EAS triggered by big bursts. The absolute intensity of the size spectrum of these combined EAS was compared with that of general EAS obtained by AS trigger. The EAS with sizes greater than 2x1 million were always accompanied by gamma-families with sigma E sub gamma H 10 TeV, n sub gamma, H 2 and Emin=3 TeV, although the rate of EAS accompaning such gamma-families decreases rapidly as their sizes decrease.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Liu, W; Ding, X; Hu, Y
Purpose: To investigate how spot size and spacing affect plan quality, especially, plan robustness and the impact of interplay effect, of robustly-optimized intensity-modulated proton therapy (IMPT) plans for lung cancer. Methods: Two robustly-optimized IMPT plans were created for 10 lung cancer patients: (1) one for a proton beam with in-air energy dependent large spot size at isocenter (σ: 5–15 mm) and spacing (1.53σ); (2) the other for a proton beam with small spot size (σ: 2–6 mm) and spacing (5 mm). Both plans were generated on the average CTs with internal-gross-tumor-volume density overridden to irradiate internal target volume (ITV). Themore » root-mean-square-dose volume histograms (RVH) measured the sensitivity of the dose to uncertainties, and the areas under RVH curves were used to evaluate plan robustness. Dose evaluation software was developed to model time-dependent spot delivery to incorporate interplay effect with randomized starting phases of each field per fraction. Patient anatomy voxels were mapped from phase to phase via deformable image registration to score doses. Dose-volume-histogram indices including ITV coverage, homogeneity, and organs-at-risk (OAR) sparing were compared using Student-t test. Results: Compared to large spots, small spots resulted in significantly better OAR sparing with comparable ITV coverage and homogeneity in the nominal plan. Plan robustness was comparable for ITV and most OARs. With interplay effect considered, significantly better OAR sparing with comparable ITV coverage and homogeneity is observed using smaller spots. Conclusion: Robust optimization with smaller spots significantly improves OAR sparing with comparable plan robustness and similar impact of interplay effect compare to larger spots. Small spot size requires the use of larger number of spots, which gives optimizer more freedom to render a plan more robust. The ratio between spot size and spacing was found to be more relevant to determine plan robustness and the impact of interplay effect than spot size alone. This research was supported by the National Cancer Institute Career Developmental Award K25CA168984, by the Fraternal Order of Eagles Cancer Research Fund Career Development Award, by The Lawrence W. and Marilyn W. Matteson Fund for Cancer Research, by Mayo Arizona State University Seed Grant, and by The Kemper Marley Foundation.« less
Evaluation of a Progressive Mobility Protocol in Postoperative Cardiothoracic Surgical Patients.
Floyd, Shawn; Craig, Sarah W; Topley, Darla; Tullmann, Dorothy
2016-01-01
Cardiothoracic surgical patients are at high risk for complications related to immobility, such as increased intensive care and hospital length of stay, intensive care unit readmission, pressure ulcer development, and deep vein thrombosis/pulmonary embolus. A progressive mobility protocol was started in the thoracic cardiovascular intensive care unit in a rural academic medical center. The purpose of the progressive mobility protocol was to increase mobilization of postoperative patients and decrease complications related to immobility in this unique patient population. A matched-pairs design was used to compare a randomly selected sample of the preintervention group (n = 30) to a matched postintervention group (n = 30). The analysis compared outcomes including intensive care unit and hospital length of stay, intensive care unit readmission occurrence, pressure ulcer prevalence, and deep vein thrombosis/pulmonary embolism prevalence between the 2 groups. Although this comparison does not achieve statistical significance (P < .05) for any of the outcomes measured, it does show clinical significance in a reduction in hospital length of stay, intensive care unit days, in intensive care unit readmission rate, and a decline in pressure ulcer prevalence, which is the overall goal of progressive mobility. This study has implications for nursing, hospital administration, and therapy services with regard to staffing and cost savings related to fewer complications of immobility. Future studies with a larger sample size and other populations are warranted.
Technical Achievements in Communist China’s Electrical Equipment Industry
1960-09-15
products has also been , developed, including long rod type insulating porcelains and a new series of line porcelains . In 1958, oil sockets for 330...is now aimed at the creation of high intensity, high insulating , and small-size high-tension porcelain products. During the past 10 years, our...of lead-covered oil-immersed paper- insulated cables of 55 kilovolts and less, rubber-sheathed cables of 6,000 volts and less, and aluminum core
NASA Astrophysics Data System (ADS)
Kusagaya, T.; Uchida, T.; Tanaka, H. K. M.; Tanaka, M.
2012-04-01
We will present a real-time monitoring system for cosmic-ray muon radiography as an application of a readout module developed by T. Uchida et al [1,2]. The readout module was developed originally for probing the internal structure of volcanoes in 2008 [3]. Its features are small in size, low power consumption, and the capability to access remotely via Ethernet. The current statistics data of cosmic-ray muons can be read from a PC placed far from the module at anytime. By using this feature, we constructed a real-time monitoring system. As a test experiment, we observed fluid movement in a cylinder with a diameter of 112 meters water equivalent. In this work, we succeeded to resolve the fluid movement in the cylinder. We varied the fluid level inside the cylinder and measured the muon intensity. We found that the muon intensity correlates inversely with the fluid level: the muon intensity increases for the lower fluid level and decreases for the higher fluid level. Although the time resolution of muon radiography was sufficient to resolve changes in the fluid level, an adequate time window has to be chosen for different operating conditions. We anticipate that this system will be applicable to exploring high-speed phenomena in a gigantic object.
A risk assessment method for multi-site damage
NASA Astrophysics Data System (ADS)
Millwater, Harry Russell, Jr.
This research focused on developing probabilistic methods suitable for computing small probabilities of failure, e.g., 10sp{-6}, of structures subject to multi-site damage (MSD). MSD is defined as the simultaneous development of fatigue cracks at multiple sites in the same structural element such that the fatigue cracks may coalesce to form one large crack. MSD is modeled as an array of collinear cracks with random initial crack lengths with the centers of the initial cracks spaced uniformly apart. The data used was chosen to be representative of aluminum structures. The structure is considered failed whenever any two adjacent cracks link up. A fatigue computer model is developed that can accurately and efficiently grow a collinear array of arbitrary length cracks from initial size until failure. An algorithm is developed to compute the stress intensity factors of all cracks considering all interaction effects. The probability of failure of two to 100 cracks is studied. Lower bounds on the probability of failure are developed based upon the probability of the largest crack exceeding a critical crack size. The critical crack size is based on the initial crack size that will grow across the ligament when the neighboring crack has zero length. The probability is evaluated using extreme value theory. An upper bound is based on the probability of the maximum sum of initial cracks being greater than a critical crack size. A weakest link sampling approach is developed that can accurately and efficiently compute small probabilities of failure. This methodology is based on predicting the weakest link, i.e., the two cracks to link up first, for a realization of initial crack sizes, and computing the cycles-to-failure using these two cracks. Criteria to determine the weakest link are discussed. Probability results using the weakest link sampling method are compared to Monte Carlo-based benchmark results. The results indicate that very small probabilities can be computed accurately in a few minutes using a Hewlett-Packard workstation.
Automated Identification of Coronal Holes from Synoptic EUV Maps
NASA Astrophysics Data System (ADS)
Hamada, Amr; Asikainen, Timo; Virtanen, Ilpo; Mursula, Kalevi
2018-04-01
Coronal holes (CHs) are regions of open magnetic field lines in the solar corona and the source of the fast solar wind. Understanding the evolution of coronal holes is critical for solar magnetism as well as for accurate space weather forecasts. We study the extreme ultraviolet (EUV) synoptic maps at three wavelengths (195 Å/193 Å, 171 Å and 304 Å) measured by the Solar and Heliospheric Observatory/Extreme Ultraviolet Imaging Telescope (SOHO/EIT) and the Solar Dynamics Observatory/Atmospheric Imaging Assembly (SDO/AIA) instruments. The two datasets are first homogenized by scaling the SDO/AIA data to the SOHO/EIT level by means of histogram equalization. We then develop a novel automated method to identify CHs from these homogenized maps by determining the intensity threshold of CH regions separately for each synoptic map. This is done by identifying the best location and size of an image segment, which optimally contains portions of coronal holes and the surrounding quiet Sun allowing us to detect the momentary intensity threshold. Our method is thus able to adjust itself to the changing scale size of coronal holes and to temporally varying intensities. To make full use of the information in the three wavelengths we construct a composite CH distribution, which is more robust than distributions based on one wavelength. Using the composite CH dataset we discuss the temporal evolution of CHs during the Solar Cycles 23 and 24.
Film Dosimetry for Intensity Modulated Radiation Therapy
NASA Astrophysics Data System (ADS)
Benites-Rengifo, J.; Martínez-Dávalos, A.; Celis, M.; Lárraga, J.
2004-09-01
Intensity Modulated Radiation Therapy (IMRT) is an oncology treatment technique that employs non-uniform beam intensities to deliver highly conformal radiation to the targets while minimizing doses to normal tissues and critical organs. A key element for a successful clinical implementation of IMRT is establishing a dosimetric verification process that can ensure that delivered doses are consistent with calculated ones for each patient. To this end we are developing a fast quality control procedure, based on film dosimetry techniques, to be applied to the 6 MV Novalis linear accelerator for IMRT of the Instituto Nacional de Neurología y Neurocirugía (INNN) in Mexico City. The procedure includes measurements of individual fluence maps for a limited number of fields and dose distributions in 3D using extended dose-range radiographic film. However, the film response to radiation might depend on depth, energy and field size, and therefore compromise the accuracy of measurements. In this work we present a study of the dependence of Kodak EDR2 film's response on the depth, field size and energy, compared with those of Kodak XV2 film. The first aim is to devise a fast and accurate method to determine the calibration curve of film (optical density vs. doses) commonly called a sensitometric curve. This was accomplished by using three types of irradiation techniques: Step-and-shoot, dynamic and static fields.
DeSantis, Michael C; DeCenzo, Shawn H; Li, Je-Luen; Wang, Y M
2010-03-29
Standard deviation measurements of intensity profiles of stationary single fluorescent molecules are useful for studying axial localization, molecular orientation, and a fluorescence imaging system's spatial resolution. Here we report on the analysis of the precision of standard deviation measurements of intensity profiles of single fluorescent molecules imaged using an EMCCD camera.We have developed an analytical expression for the standard deviation measurement error of a single image which is a function of the total number of detected photons, the background photon noise, and the camera pixel size. The theoretical results agree well with the experimental, simulation, and numerical integration results. Using this expression, we show that single-molecule standard deviation measurements offer nanometer precision for a large range of experimental parameters.
Li, Ting; Zhong, Fulin; Pan, Boan; Li, Zebin; Huang, Chong; Deng, Zishan
2017-01-01
The optoelectronic sensor OPT101 have merits in advanced optoelectronic response characteristics at wavelength range for medical near-infrared spectroscopy and small-size chip design with build-in trans-impedance amplifier. Our lab is devoted to developing a series of portable near-infrared spectroscopy (NIRS) devices embedded with OPT101 for applications in intensive care unit clinics, based on NIRS principle. Here we review the characteristics and advantages of OPT101 relative to clinical NIRS instrumentation, and the most recent achievements, including early-diagnosis and therapeutic effect evaluation of thrombus, noninvasive monitoring of patients' shock severity, and fatigue evaluation. The future prospect on OPT101 improvements in noninvasive clinical applications is also discussed. PMID:28757564
Intensive Education: How It Affects Teachers' and Students' Work Conditions.
ERIC Educational Resources Information Center
Fallon, Karin
This qualitative study of a high school using intensive education shows how teaching and learning were improved when teachers taught and students attended one class daily for 6 weeks. Intensive education is an alternative scheduling and organizational format that reduces class size and extends class length by having teachers and students in one…
NASA Astrophysics Data System (ADS)
Spiteri, M.; Lewis, E.; Windridge, D.; Avula, S.
2015-03-01
Up to 25% of children who undergo brain tumour resection surgery in the posterior fossa develop posterior fossa syndrome (PFS). This syndrome is characterised by mutism and disturbance in speech. Our hypothesis is that there is a correlation between PFS and the occurrence of hypertrophic olivary degeneration (HOD) in lobes within the posterior fossa, known as the inferior olivary nuclei (ION). HOD is exhibited as an increase in size and intensity of the ION on an MR image. Intra-operative MRI (IoMRI) is used during surgical procedures at the Alder Hey Children's Hospital, Liver- pool, England, in the treatment of Posterior Fossa tumours and allows visualisation of the brain during surgery. The final MR scan on the IoMRI allows early assessment of the ION immediately after the surgical procedure. The longitudinal MRI data of 28 patients was analysed in a collaborative study with Alder Hey Children's Hospital, in order to identify the most relevant imaging features that relate to the development of PFS, specifically related to HOD. A semi-automated segmentation process was carried out to delineate the ION on each MRI. Feature selection techniques were used to identify the most relevant features amongst the MRI data, demographics and clinical data provided by the hospital. A support vector machine (SVM) was used to analyse the discriminative ability of the selected features. The results indicate the presence of HOD as the most efficient feature that correlates with the development of PFS, followed by the change in intensity and size of the ION and whether HOD occurred bilaterally or unilaterally.
Campo, J L; Turrado, H
1997-01-12
The effects of population size and selection intensity on the short-term response to selection were investigated in an experiment with Tribolium, using a two-trait empirical selection index for pupal and adult weights. Twenty lines were selected following a factorial design of five population sizes (1, 2, 4, 8, and 16 pairs of parents) and four selection intensities (20, 25, 33, and 50%), with three replicates. For each replicate, an unselected control with 16 pairs of parents was produced. There were four generations of selection per line. Selection response was significant in all lines with the 20% selection intensity and/or the 16-pair population size. Selection intensity and population size were significant effects and there was significant interaction between them. Higher selection intensities produced more overall significant response to selection (20% > (25% = 33%) > 50%); this significance was also found for the 16-pair population size. There was an overall significant difference among population sizes, with the larger population sizes giving more response than the smaller sizes (16-pair = 8-pair = 4-pair) > (2-pair = 1-pair); this significance was also found for the 20% selection intensity. There was a good agreement between observed and expected responses, except for the 50% selection intensity and/or 1-pair population size; expected values in generation 1 overestimated observed values. The realized heritability was similar in all lines. With equal and high numbers of individuals scored, it was better to choose a high selection intensity than a large population size. The results show that the effect of population size cannot be ignored, even in short-term selection response; the main influence of population size is through selection differential. RESUMEN: Los efectos del tamaño de población y la intensidad de selección sobre la respuesta a corto plazo para un índice de selección en Tribolium Los efectos del tamaño de población y la intensidad de selección sobre la respuesta a la selección a corto plazo fueron estudiados en un experimento con Tribolium usando un índice empírico de selección para dos caracteres (peso de pupa y peso adulto). Se seleccionaron 20 líneas siguiendo un modelo factorial de cinco tamaños de población (1, 2, 4, 8 y 16 pares de padres) y cuatro intensidades de selección (20, 25, 33 y 50%), con tres repeticiones. En cada repetición, había una línea control sin seleccionar con 16 pares de padres. Se hicieron cuatro generaciones de selección, por línea. La respuesta a la selección fue significativa en todas las líneas con el 20% de intensidad de selección y/o 16 pares de padres. Tanto la intensidad de selección como el tamaño de población fueron efectos significativos y hubo interacción significativa entre ellos. Las intensidades de selección más altas produjeron significativamente más respuesta en general (20% > (25% = 33%) > 50%), y esta significación se mantenía cuando el tamaño de población era de 16 pares de padres. Hubo diferencias significativas entre tamaños de población, dando los mayores tamaños más respuesta en general que los menores tamaños (16 pares = 8 pares = 4 pares) > (2 pares = 1 par), manteniendose esta significación para la intensidad de selección del 20%. La concordancia entre las respuestas observadas y las esperadas era buena, excepto cuando la intensidad de selección era 50% y/o el tamaño de población era 1 par de padres; los valores esperados en la generación 1 sobreestimaban los valores observados. La heredabilidad realizada fue similar en todas las líneas. Cuando el número total de animales era igual y alto, era mejor elegir una intensidad de selección alta que un tamaño de población grande. Los resultados indican que el efecto del tamaño de población no se puede ignorar incluso en experimentos de selección a corto plazo, y que la influencia principal de este efecto es a través del diferencial de selección. 1997 Blackwell Verlag GmbH.
NASA Astrophysics Data System (ADS)
Fan, Ranran; Lu, Fei; Li, Kaikai; Liu, Kaijing
2018-06-01
This paper investigated the controllable growth of Ge nanocrystal (nc-Ge) in (Ge, Er) co-doped ZnO film, and the relationship between the size of nc-Ge and the enhancement of Er3+ related 1.54 μm photoluminescence (PL). It was found that nc-Ge with size of ∼5 nm was formed by annealing treatment at 600 °C. The intensity of 1.54 μm was significantly enhanced due to the existence of nc-Ge and showed an obvious dependence on nanocrystal size. The size of nc-Ge increased with the increase of the annealing temperature, and the nanocrystal with size of ∼5 nm made the most obvious contribution to PL enhancement. Prolonging annealing time could improve the crystalline structure of ZnO matrix but had no effect on PL intensity. The experimental results showed that the PL enhancement was mainly achieved by transferring the energy to Er through the resonance absorption of nc-Ge.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Öztürk, Hande; Noyan, I. Cevdet
A rigorous study of sampling and intensity statistics applicable for a powder diffraction experiment as a function of crystallite size is presented. Our analysis yields approximate equations for the expected value, variance and standard deviations for both the number of diffracting grains and the corresponding diffracted intensity for a given Bragg peak. The classical formalism published in 1948 by Alexander, Klug & Kummer [J. Appl. Phys.(1948),19, 742–753] appears as a special case, limited to large crystallite sizes, here. It is observed that both the Lorentz probability expression and the statistics equations used in the classical formalism are inapplicable for nanocrystallinemore » powder samples.« less
Öztürk, Hande; Noyan, I. Cevdet
2017-08-24
A rigorous study of sampling and intensity statistics applicable for a powder diffraction experiment as a function of crystallite size is presented. Our analysis yields approximate equations for the expected value, variance and standard deviations for both the number of diffracting grains and the corresponding diffracted intensity for a given Bragg peak. The classical formalism published in 1948 by Alexander, Klug & Kummer [J. Appl. Phys.(1948),19, 742–753] appears as a special case, limited to large crystallite sizes, here. It is observed that both the Lorentz probability expression and the statistics equations used in the classical formalism are inapplicable for nanocrystallinemore » powder samples.« less
NASA Technical Reports Server (NTRS)
Kumar, Anil; Done, James; Dudhia, Jimy; Niyogi, Dev
2011-01-01
The predictability of Cyclone Sidr in the Bay of Bengal was explored in terms of track and intensity using the Advanced Research Hurricane Weather Research Forecast (AHW) model. This constitutes the first application of the AHW over an area that lies outside the region of the North Atlantic for which this model was developed and tested. Several experiments were conducted to understand the possible contributing factors that affected Sidr s intensity and track simulation by varying the initial start time and domain size. Results show that Sidr s track was strongly controlled by the synoptic flow at the 500-hPa level, seen especially due to the strong mid-latitude westerly over north-central India. A 96-h forecast produced westerly winds over north-central India at the 500-hPa level that were notably weaker; this likely caused the modeled cyclone track to drift from the observed actual track. Reducing the model domain size reduced model error in the synoptic-scale winds at 500 hPa and produced an improved cyclone track. Specifically, the cyclone track appeared to be sensitive to the upstream synoptic flow, and was, therefore, sensitive to the location of the western boundary of the domain. However, cyclone intensity remained largely unaffected by this synoptic wind error at the 500-hPa level. Comparison of the high resolution, moving nested domain with a single coarser resolution domain showed little difference in tracks, but resulted in significantly different intensities. Experiments on the domain size with regard to the total precipitation simulated by the model showed that precipitation patterns and 10-m surface winds were also different. This was mainly due to the mid-latitude westerly flow across the west side of the model domain. The analysis also suggested that the total precipitation pattern and track was unchanged when the domain was extended toward the east, north, and south. Furthermore, this highlights our conclusion that Sidr was influenced from the west side of the domain. The displacement error was significantly reduced after the domain size from the western model boundary was decreased. Study results demonstrate the capability and need of a high-resolution mesoscale modeling framework for simulating the complex interactions that contribute to the formation of tropical cyclones over the Bay of Bengal region
Barakat, Abdellatif; de Vries, Hugo; Rouau, Xavier
2013-04-01
The use of lignocellulosic biomass is promising for biofuels and materials and new technologies for the conversion need to be developed. However, the inherent properties of native lignocellulosic materials make them resistant to enzymatic and chemical degradation. Lignocellulosic biomass requires being pretreated to change the physical and chemical properties of lignocellulosic matrix in order to increase cell wall polymers accessibility and bioavailability. Mechanical size reduction may be chemical free intensive operation thanks to decreasing particles size and cellulose crystallinity, and increasing accessible surface area. Changes in these parameters improve the digestibility and the bioconversion of lignocellulosic biomass. However, mechanical size reduction requires cost-effective approaches from an energy input point of view. Therefore, the energy consumption in relation to physicochemical properties of lignocellulosic biomass was discussed. Even more, chemical treatments combined with physicochemical size reduction approaches are proposed to reduce energy consumption in this review. Copyright © 2013 Elsevier Ltd. All rights reserved.
Kinetics of antigen binding to arrays of antibodies in different sized spots
NASA Technical Reports Server (NTRS)
Sapsford, K. E.; Liron, Z.; Shubin, Y. S.; Ligler, F. S.
2001-01-01
A fluorescence-based array biosensor has been developed which can measure the binding kinetics of an antigen to an immobilized antibody in real time. A patterned array of antibodies immobilized on the surface of a planar waveguide was used to capture a Cy5-labeled antigen present in a solution that was continuously flowed over the surface. The CCD image of the waveguide was monitored continuously for 25 min. The resulting exponential rise in fluorescence signal was determined by image analysis software and fitted to a reaction-limited kinetics model, giving a kf of 3.6 x 10(5) M(-1) s(-1). Different spot sizes were then patterned on the surface of the waveguide using either a PDMS flow cell or laser exposure, producing width sizes ranging from 80 to 1145 microm. It was demonstrated that under flow conditions, the reduction of spot size did not alter the association rate of the antigen with immobilized antibody; however, as the spot width decreased to < 200 nm, the signal intensity also decreased.
Kinetic energy distribution of multiply charged ions in Coulomb explosion of Xe clusters.
Heidenreich, Andreas; Jortner, Joshua
2011-02-21
We report on the calculations of kinetic energy distribution (KED) functions of multiply charged, high-energy ions in Coulomb explosion (CE) of an assembly of elemental Xe(n) clusters (average size (n) = 200-2171) driven by ultra-intense, near-infrared, Gaussian laser fields (peak intensities 10(15) - 4 × 10(16) W cm(-2), pulse lengths 65-230 fs). In this cluster size and pulse parameter domain, outer ionization is incomplete∕vertical, incomplete∕nonvertical, or complete∕nonvertical, with CE occurring in the presence of nanoplasma electrons. The KEDs were obtained from double averaging of single-trajectory molecular dynamics simulation ion kinetic energies. The KEDs were doubly averaged over a log-normal cluster size distribution and over the laser intensity distribution of a spatial Gaussian beam, which constitutes either a two-dimensional (2D) or a three-dimensional (3D) profile, with the 3D profile (when the cluster beam radius is larger than the Rayleigh length) usually being experimentally realized. The general features of the doubly averaged KEDs manifest the smearing out of the structure corresponding to the distribution of ion charges, a marked increase of the KEDs at very low energies due to the contribution from the persistent nanoplasma, a distortion of the KEDs and of the average energies toward lower energy values, and the appearance of long low-intensity high-energy tails caused by the admixture of contributions from large clusters by size averaging. The doubly averaged simulation results account reasonably well (within 30%) for the experimental data for the cluster-size dependence of the CE energetics and for its dependence on the laser pulse parameters, as well as for the anisotropy in the angular distribution of the energies of the Xe(q+) ions. Possible applications of this computational study include a control of the ion kinetic energies by the choice of the laser intensity profile (2D∕3D) in the laser-cluster interaction volume.
Interspecific competition alters nonlinear selection on offspring size in the field.
Marshall, Dustin J; Monro, Keyne
2013-02-01
Offspring size is one of the most important life-history traits with consequences for both the ecology and evolution of most organisms. Surprisingly, formal estimates of selection on offspring size are rare, and the degree to which selection (particularly nonlinear selection) varies among environments remains poorly explored. We estimate linear and nonlinear selection on offspring size, module size, and senescence rate for a sessile marine invertebrate in the field under three different intensities of interspecific competition. The intensity of competition strongly modified the strength and form of selection acting on offspring size. We found evidence for differences in nonlinear selection across the three environments. Our results suggest that the fitness returns of a given offspring size depend simultaneously on their environmental context, and on the context of other offspring traits. Offspring size effects can be more pervasive with regards to their influence on the fitness returns of other traits than previously recognized, and we suggest that the evolution of offspring size cannot be understood in isolation from other traits. Overall, variability in the form and strength of selection on offspring size in nature may reduce the efficacy of selection on offspring size and maintain variation in this trait. © 2012 The Author(s). Evolution© 2012 The Society for the Study of Evolution.
Online submicron particle sizing by dynamic light scattering using autodilution
NASA Technical Reports Server (NTRS)
Nicoli, David F.; Elings, V. B.
1989-01-01
Efficient production of a wide range of commercial products based on submicron colloidal dispersions would benefit from instrumentation for online particle sizing, permitting real time monitoring and control of the particle size distribution. Recent advances in the technology of dynamic light scattering (DLS), especially improvements in algorithms for inversion of the intensity autocorrelation function, have made it ideally suited to the measurement of simple particle size distributions in the difficult submicron region. Crucial to the success of an online DSL based instrument is a simple mechanism for automatically sampling and diluting the starting concentrated sample suspension, yielding a final concentration which is optimal for the light scattering measurement. A proprietary method and apparatus was developed for performing this function, designed to be used with a DLS based particle sizing instrument. A PC/AT computer is used as a smart controller for the valves in the sampler diluter, as well as an input-output communicator, video display and data storage device. Quantitative results are presented for a latex suspension and an oil-in-water emulsion.
Alloy 740H Component Manufacturing Development
NASA Astrophysics Data System (ADS)
de Barbadillo, J. J.; Baker, B. A.; Gollihue, R. D.; Patel, S. J.
Alloy 740H was developed specifically for use in A-USC power plants. This alloy has been intensively evaluated in collaborative programs throughout the world, and the key properties have been verified and documented. In 2011 the alloy was approved for use in welded construction under ASME Code Case 2702. At present, alloy 740H is the only age-hardened nickel-base alloy that is ASME code approved. The emphasis for A-USC materials development is now on verification of the metalworking industry's capability to make the full range of mill product forms and sizes and to produce fittings and fabrications required for construction of a power plant. This paper presents the results of recent developments in component manufacture and evaluation.
Grain size indicators of sedimentary coupling between hillslopes and channels in a dryland basin
NASA Astrophysics Data System (ADS)
Hollings, Rory; Michealides, Katerina; Bliss Singer, Michael
2017-04-01
In dryland landscapes, heterogeneous and short-lived rainstorms generate runoff on slopes and streamflow in channels, which drive sediment movement from hillslope surfaces to channels and the transport of bed material sediment within channels. Long-term topographic evolution of drainage basins is partly determined by the relative balance of hillslope sediment supply to channels and the evacuation of channel sediment. However, it is not clear whether supply or evacuation is dominant over longer timescales (>>100 y) within dryland basins. One important indicator of local cumulative sediment transport is grain size (GS). On dryland hillslopes, grain size is governed over long timescales by weathering, but on short time scales (events to decades), is controlled by event-driven transport of the debris mantle. In the channel, GS reflects the input of hillslope sediment and the selective transport of particles along the bed. It is currently unknown how these two processes are expressed systematically within GS distributions on slopes and in channels within drylands, but this information could be useful to explain the history of the relative balance between hillslope sediment supply to channels and net sediment transport in the channel. We investigate this problem by combining field measurements of surface sediment grain size distributions in channels and on hillslopes with 1m LiDAR topography, >60 years of rainfall and channel discharge data from the Walnut Gulch Experimental Watershed (WGEW) in Arizona, and simple calculations of grain-sized based local stress distributions for various rainfall and discharge events. Hydrological scenarios of overland flow on hillslopes and channel flow conditions were derived from distributions of historic data at WGEW and were selected to reflect the wide range of storm intensities and durations, and channel discharges. 1) We used three quartiles of the entire distribution of measured discharge values for 80 locations throughout the channel network to represent low, medium and high flows. 2) For rainfall we used three quartiles of the entire distribution of measured rainfall intensity and duration from 85 rain gauges spanning the basin, to derive low, medium and high rainfall durations. We then calculated the corresponding rainfall intensities based on four intensity-duration curves that were characteristic of different parts of the phase space of the measured data-points. 3) The derived rainfall intensities and durations were converted into hillslope overland flow using Coup2D (a hillslope rainfall-runoff model) for 44 hillslopes within WGEW for which we have GS and topographic data. We employ the median grain size (D50) to compare stress metrics on hillslopes and in channel for each location. Typically, low-order streams experience greater influxes of hillslope derived sediment than is evacuated by the channel. However, the main channel stem is characterised by sediment removal in most scenarios including low discharge, long duration rainfall, suggesting most hillslope supplied sediment is balanced by channel evacuation. Near tributary junctions, and close to the mouth of the basin there are fluctuations in net balance of sediment transport from evacuation- to supply-dominance for different scenarios. These fluctuations could influence channel bed GS distribution and longitudinal profile development.
NASA Astrophysics Data System (ADS)
Yoshida, Yuki; Kitamoto, Shunji; Hoshino, Akio
2017-11-01
The X-ray line diagnostic method is a powerful tool for an investigation of plasma around accretion-powered X-ray pulsars. We point out an apparent intensity modulation of emission lines, with their rotation period of neutron stars, due to the finite speed of light (we call this effect the “finite light speed effect”) if the line emission mechanism is a kind of reprocessing, such as fluorescence or recombination after ionization by X-ray irradiation from pulsars. The modulation amplitude is determined by the size of the emission region, which is in competition with the smearing effect by the light crossing time in the emission region. This is efficient if the size of the emission region is roughly comparable to that of the rotation period multiplied by the speed of light. We apply this effect to a symbiotic X-ray pulsar, GX 1+4, where a spin modulation of the intense iron line of which has been reported. The finite light speed effect can explain the observed intensity modulation if its fluorescent region is the size of ˜ {10}12 cm.
Moderate and late preterm birth: effect on brain size and maturation at term-equivalent age.
Walsh, Jennifer M; Doyle, Lex W; Anderson, Peter J; Lee, Katherine J; Cheong, Jeanie L Y
2014-10-01
To compare the size of multiple brain structures, maturation in terms of both brain myelination and gyral development, and evidence of brain injury between moderate and late preterm (MLPT) and term-born infants at term-equivalent age. The study was approved by the human research ethics committees of the participating hospitals, and informed parental consent was obtained for all infants. One hundred ninety-nine MLPT and 50 term-born infants underwent 3-T magnetic resonance (MR) imaging brain examinations at 38-44 weeks of corrected gestational age. T1- and T2-weighted MR images were compared between groups for size of multiple cerebral structures, degree of myelination in the posterior limb of the internal capsule, gyral maturation, signal intensity abnormalities, and presence of cysts by a single assessor who was blinded to the gestational group and perinatal course of the infants. Group differences were compared by using linear regression for continuous variables and logistic regression for categorical variables, and interrater and intrarater reliability was assessed by using intraclass correlation coefficients. Compared with those in the term-born control group, measurements of brain biparietal diameter, corpus callosum, basal ganglia and thalami, and cerebellum were smaller in infants in the MLPT group (all P ≤ .01), while extracerebral space was larger (P < .0001). Myelination of the posterior limb of the internal capsule was less developed, and gyral maturation was delayed in the MLPT group (both P < .001). Signal intensity abnormalities and cysts were uncommon in both groups, with 13 (6.5%) MLPT infants and one (2%) term infant having abnormalities. Inter- and intrarater reliability was good for most measures, with intraclass correlation coefficients generally greater than 0.68. MLPT birth is associated with smaller brain size, less-developed myelination of the posterior limb of the internal capsule, and more immature gyral folding than those associated with full-term birth. These brain changes may form the basis of some of the long-term neurodevelopmental deficits observed in MLPT children. Online supplemental material is available for this article. © RSNA, 2014.
Liu, Chenbin; Schild, Steven E; Chang, Joe Y; Liao, Zhongxing; Korte, Shawn; Shen, Jiajian; Ding, Xiaoning; Hu, Yanle; Kang, Yixiu; Keole, Sameer R; Sio, Terence T; Wong, William W; Sahoo, Narayan; Bues, Martin; Liu, Wei
2018-06-01
To investigate how spot size and spacing affect plan quality, robustness, and interplay effects of robustly optimized intensity modulated proton therapy (IMPT) for lung cancer. Two robustly optimized IMPT plans were created for 10 lung cancer patients: first by a large-spot machine with in-air energy-dependent large spot size at isocenter (σ: 6-15 mm) and spacing (1.3 σ), and second by a small-spot machine with in-air energy-dependent small spot size (σ: 2-6 mm) and spacing (5 mm). Both plans were generated by optimizing radiation dose to internal target volume on averaged 4-dimensional computed tomography scans using an in-house-developed IMPT planning system. The dose-volume histograms band method was used to evaluate plan robustness. Dose evaluation software was developed to model time-dependent spot delivery to incorporate interplay effects with randomized starting phases for each field per fraction. Patient anatomy voxels were mapped phase-to-phase via deformable image registration, and doses were scored using in-house-developed software. Dose-volume histogram indices, including internal target volume dose coverage, homogeneity, and organs at risk (OARs) sparing, were compared using the Wilcoxon signed-rank test. Compared with the large-spot machine, the small-spot machine resulted in significantly lower heart and esophagus mean doses, with comparable target dose coverage, homogeneity, and protection of other OARs. Plan robustness was comparable for targets and most OARs. With interplay effects considered, significantly lower heart and esophagus mean doses with comparable target dose coverage and homogeneity were observed using smaller spots. Robust optimization with a small spot-machine significantly improves heart and esophagus sparing, with comparable plan robustness and interplay effects compared with robust optimization with a large-spot machine. A small-spot machine uses a larger number of spots to cover the same tumors compared with a large-spot machine, which gives the planning system more freedom to compensate for the higher sensitivity to uncertainties and interplay effects for lung cancer treatments. Copyright © 2018 Elsevier Inc. All rights reserved.
Constraining ejecta particle size distributions with light scattering
NASA Astrophysics Data System (ADS)
Schauer, Martin; Buttler, William; Frayer, Daniel; Grover, Michael; Lalone, Brandon; Monfared, Shabnam; Sorenson, Daniel; Stevens, Gerald; Turley, William
2017-06-01
The angular distribution of the intensity of light scattered from a particle is strongly dependent on the particle size and can be calculated using the Mie solution to Maxwell's equations. For a collection of particles with a range of sizes, the angular intensity distribution will be the sum of the contributions from each particle size weighted by the number of particles in that size bin. The set of equations describing this pattern is not uniquely invertible, i.e. a number of different distributions can lead to the same scattering pattern, but with reasonable assumptions about the distribution it is possible to constrain the problem and extract estimates of the particle sizes from a measured scattering pattern. We report here on experiments using particles ejected by shockwaves incident on strips of triangular perturbations machined into the surface of tin targets. These measurements indicate a bimodal distribution of ejected particle sizes with relatively large particles (median radius 2-4 μm) evolved from the edges of the perturbation strip and smaller particles (median radius 200-600 nm) from the perturbations. We will briefly discuss the implications of these results and outline future plans.
Size-effect of oligomeric cholesteric liquid-crystal microlenses on the optical specifications.
Bayon, Chloé; Agez, Gonzague; Mitov, Michel
2015-10-15
In cholesteric liquid-crystalline microlenses, we have studied the role of the microlens size on the focused light intensity and the focal length. We have found that the intensity is maximized by aiming a specific range for the diameter and the thickness of microlenses and that the focal length is adjusted by controlling the diameter and the annealing time of the optical film. Cholesteric microlenses may be used as wavelength-tunable directional light sources in organic soft-matter circuits.
A probabilistic tornado wind hazard model for the continental United States
DOE Office of Scientific and Technical Information (OSTI.GOV)
Hossain, Q; Kimball, J; Mensing, R
A probabilistic tornado wind hazard model for the continental United States (CONUS) is described. The model incorporates both aleatory (random) and epistemic uncertainties associated with quantifying the tornado wind hazard parameters. The temporal occurrences of tornadoes within the continental United States (CONUS) is assumed to be a Poisson process. A spatial distribution of tornado touchdown locations is developed empirically based on the observed historical events within the CONUS. The hazard model is an aerial probability model that takes into consideration the size and orientation of the facility, the length and width of the tornado damage area (idealized as a rectanglemore » and dependent on the tornado intensity scale), wind speed variation within the damage area, tornado intensity classification errors (i.e.,errors in assigning a Fujita intensity scale based on surveyed damage), and the tornado path direction. Epistemic uncertainties in describing the distributions of the aleatory variables are accounted for by using more than one distribution model to describe aleatory variations. The epistemic uncertainties are based on inputs from a panel of experts. A computer program, TORNADO, has been developed incorporating this model; features of this program are also presented.« less
Time Variations in Forecasts and Occurrences of Large Solar Energetic Particle Events
NASA Astrophysics Data System (ADS)
Kahler, S. W.
2015-12-01
The onsets and development of large solar energetic (E > 10 MeV) particle (SEP) events have been characterized in many studies. The statistics of SEP event onset delay times from associated solar flares and coronal mass ejections (CMEs), which depend on solar source longitudes, can be used to provide better predictions of whether a SEP event will occur following a large flare or fast CME. In addition, size distributions of peak SEP event intensities provide a means for a probabilistic forecast of peak intensities attained in observed SEP increases. SEP event peak intensities have been compared with their rise and decay times for insight into the acceleration and transport processes. These two time scales are generally treated as independent parameters describing the development of a SEP event, but we can invoke an alternative two-parameter description based on the assumption that decay times exceed rise times for all events. These two parameters, from the well known Weibull distribution, provide an event description in terms of its basic shape and duration. We apply this distribution to several large SEP events and ask what the characteristic parameters and their dependence on source longitudes can tell us about the origins of these important events.
Boundary Dpp promotes growth of medial and lateral regions of the Drosophila wing.
Barrio, Lara; Milán, Marco
2017-07-04
The gradient of Decapentaplegic (Dpp) in the Drosophila wing has served as a paradigm to characterize the role of morphogens in regulating patterning. However, the role of this gradient in regulating tissue size is a topic of intense debate as proliferative growth is homogenous. Here, we combined the Gal4/UAS system and a temperature-sensitive Gal80 molecule to induce RNAi-mediated depletion of dpp and characterise the spatial and temporal requirement of Dpp in promoting growth. We show that Dpp emanating from the AP compartment boundary is required throughout development to promote growth by regulating cell proliferation and tissue size. Dpp regulates growth and proliferation rates equally in central and lateral regions of the developing wing appendage and reduced levels of Dpp affects similarly the width and length of the resulting wing. We also present evidence supporting the proposal that graded activity of Dpp is not an absolute requirement for wing growth.
Yoon, Sung Jin; Lee, Moon Jin; Lee, Hyo Min; Lee, Jin Seok
2017-10-01
Several recent studies have reported that heat stress stimulates the activation of heat shock protein 72 (HSP72), leading to an increase in muscle synthesis. Some studies suggested that low-intensity resistance training combined with heat stress could improve muscle size and strength. This study aimed to identify the effect of low-intensity resistance training with heat stress over 12 weeks on the HSP72, anabolic hormones, muscle size, and strength in elderly women. The subjects were physically healthy women of 65-75 years, who were randomly assigned to one of three groups: a low-intensity resistance training with heating sheet group (HRT group, n = 8), a moderate-intensity resistance training (RT group, n = 6), and a heating sheet group (HEAT group, n = 7). Computed tomography scans, 1-repetition maximum (1RM), and blood samples were taken pre- and post-training. The HSP72 did not vary significantly between the different groups and times. The IGF-1 and 1RM had significantly increased in all three groups after the training (respectively, p < 0.05). Moreover, the cross-sectional area (CSA) of the quadriceps showed a significantly greater increase in the HRT group than in the HEAT group (p < 0.05). We found that low-intensity training with heat stress stimulated the anabolic hormones of elderly women, improving their muscle strength and hypertrophy. We believe that low-intensity training with heat stress is an effective way to prevent muscle atrophy and to improve muscle strength in elderly women.
Rakhmatullina, Ekaterina; Bossen, Anke; Bachofner, Kai K; Meier, Christoph; Lussi, Adrian
2013-11-01
Application of the specular reflection intensity was previously reported for the quantification of early dental erosion. Further development of the technique and assembly of the miniaturized pen-size instrument are described. The optical system was adjusted to fit into a handy device which could potentially access different positions in the oral cavity. The assembled instrument could successfully detect early erosion progression in both polished (n=70) and native (n=20) human enamels. Different severities of enamel erosion were induced by varying incubation time of polished enamel in 1% citric acid (pH=3.60, 0.5 to 10 min), while the native incisors were treated in the commercial orange juice (Tropicana Pure Premium®, pH=3.85, 10 to 60 min). The instrument provided a good differentiation between various severities of the erosion in vitro. The size of the measurement spot affected the erosion monitoring in native enamel (human incisors). The erosion measurement in the 0.7-mm (diameter) cervical spots showed systematically lower reflection intensities compared with the analysis of central and incisal small spots. The application of larger spot areas (2.3 mm) for the erosion monitoring revealed no effect (p>0.05) of the spot position on the reflection signal. High variation of the teeth susceptibility toward in vitro erosion was detected in native enamel.
Interlinking backscatter, grain size and benthic community structure
NASA Astrophysics Data System (ADS)
McGonigle, Chris; Collier, Jenny S.
2014-06-01
The relationship between acoustic backscatter, sediment grain size and benthic community structure is examined using three different quantitative methods, covering image- and angular response-based approaches. Multibeam time-series backscatter (300 kHz) data acquired in 2008 off the coast of East Anglia (UK) are compared with grain size properties, macrofaunal abundance and biomass from 130 Hamon and 16 Clamshell grab samples. Three predictive methods are used: 1) image-based (mean backscatter intensity); 2) angular response-based (predicted mean grain size), and 3) image-based (1st principal component and classification) from Quester Tangent Corporation Multiview software. Relationships between grain size and backscatter are explored using linear regression. Differences in grain size and benthic community structure between acoustically defined groups are examined using ANOVA and PERMANOVA+. Results for the Hamon grab stations indicate significant correlations between measured mean grain size and mean backscatter intensity, angular response predicted mean grain size, and 1st principal component of QTC analysis (all p < 0.001). Results for the Clamshell grab for two of the methods have stronger positive correlations; mean backscatter intensity (r2 = 0.619; p < 0.001) and angular response predicted mean grain size (r2 = 0.692; p < 0.001). ANOVA reveals significant differences in mean grain size (Hamon) within acoustic groups for all methods: mean backscatter (p < 0.001), angular response predicted grain size (p < 0.001), and QTC class (p = 0.009). Mean grain size (Clamshell) shows a significant difference between groups for mean backscatter (p = 0.001); other methods were not significant. PERMANOVA for the Hamon abundance shows benthic community structure was significantly different between acoustic groups for all methods (p ≤ 0.001). Overall these results show considerable promise in that more than 60% of the variance in the mean grain size of the Clamshell grab samples can be explained by mean backscatter or acoustically-predicted grain size. These results show that there is significant predictive capacity for sediment characteristics from multibeam backscatter and that these acoustic classifications can have ecological validity.
Large-scale atomistic calculations of clusters in intense x-ray pulses
DOE Office of Scientific and Technical Information (OSTI.GOV)
Ho, Phay J.; Knight, Chris
Here, we present the methodology of our recently developed Monte-Carlo/ Molecular-Dynamics method for studying the fundamental ultrafast dynamics induced by high-fluence, high-intensity x-ray free electron laser (XFEL) pulses in clusters. The quantum nature of the initiating ionization process is accounted for by a Monte Carlo method to calculate probabilities of electronic transitions, including photo absorption, inner-shell relaxation, photon scattering, electron collision and recombination dynamics, and thus track the transient electronic configurations explicitly. The freed electrons and ions are followed by classical particle trajectories using a molecular dynamics algorithm. These calculations reveal the surprising role of electron-ion recombination processes that leadmore » to the development of nonuniform spatial charge density profiles in x-ray excited clusters over femtosecond timescales. In the high-intensity limit, it is important to include the recombination dynamics in the calculated scattering response even for a 2- fs pulse. We also demonstrate that our numerical codes and algorithms can make e!cient use of the computational power of massively parallel supercomputers to investigate the intense-field dynamics in systems with increasing complexity and size at the ultrafast timescale and in non-linear x-ray interaction regimes. In particular, picosecond trajectories of XFEL clusters with attosecond time resolution containing millions of particles can be e!ciently computed on upwards of 262,144 processes.« less
Samkoe, Kimberley S; Bates, Brent D; Tselepidakis, Niki N; DSouza, Alisha V; Gunn, Jason R; Ramkumar, Dipak B; Paulsen, Keith D; Pogue, Brian W; Henderson, Eric R
2017-12-01
Wide local excision (WLE) of tumors with negative margins remains a challenge because surgeons cannot directly visualize the mass. Fluorescence-guided surgery (FGS) may improve surgical accuracy; however, conventional methods with direct surface tumor visualization are not immediately applicable, and properties of tissues surrounding the cancer must be considered. We developed a phantom model for sarcoma resection with the near-infrared fluorophore IRDye 800CW and used it to iteratively define the properties of connective tissues that typically surround sarcoma tumors. We then tested the ability of a blinded surgeon to resect fluorescent tumor-simulating inclusions with ∼1-cm margins using predetermined target fluorescence intensities and a Solaris open-air fluorescence imaging system. In connective tissue-simulating phantoms, fluorescence intensity decreased with increasing blood concentration and increased with increasing intralipid concentrations. Fluorescent inclusions could be resolved at ≥1-cm depth in all inclusion concentrations and sizes tested. When inclusion depth was held constant, fluorescence intensity decreased with decreasing volume. Using targeted fluorescence intensities, a blinded surgeon was able to successfully excise inclusions with ∼1-cm margins from fat- and muscle-simulating phantoms with inclusion-to-background contrast ratios as low as 2∶1. Indirect, subsurface FGS is a promising tool for surgical resection of cancers requiring WLE. (2017) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE).
Large-scale atomistic calculations of clusters in intense x-ray pulses
Ho, Phay J.; Knight, Chris
2017-04-28
Here, we present the methodology of our recently developed Monte-Carlo/ Molecular-Dynamics method for studying the fundamental ultrafast dynamics induced by high-fluence, high-intensity x-ray free electron laser (XFEL) pulses in clusters. The quantum nature of the initiating ionization process is accounted for by a Monte Carlo method to calculate probabilities of electronic transitions, including photo absorption, inner-shell relaxation, photon scattering, electron collision and recombination dynamics, and thus track the transient electronic configurations explicitly. The freed electrons and ions are followed by classical particle trajectories using a molecular dynamics algorithm. These calculations reveal the surprising role of electron-ion recombination processes that leadmore » to the development of nonuniform spatial charge density profiles in x-ray excited clusters over femtosecond timescales. In the high-intensity limit, it is important to include the recombination dynamics in the calculated scattering response even for a 2- fs pulse. We also demonstrate that our numerical codes and algorithms can make e!cient use of the computational power of massively parallel supercomputers to investigate the intense-field dynamics in systems with increasing complexity and size at the ultrafast timescale and in non-linear x-ray interaction regimes. In particular, picosecond trajectories of XFEL clusters with attosecond time resolution containing millions of particles can be e!ciently computed on upwards of 262,144 processes.« less
Theoretical Infrared Spectra for Polycyclic Aromatic Hydrocarbon Neutrals, Cations and Anions
NASA Technical Reports Server (NTRS)
Langhoff, Stephen R.
1995-01-01
Calculations are carried out using density functional theory (DFT) to determine the harmonic frequencies and intensities of the neutrals and cations of thirteen polycyclic aromatic hydrocarbons (PAHs) up to the size of ovalene. Calculations are also carried out for a few PAH anions. The DFT harmonic frequencies, when uniformly scaled by the factor of 0.958 to account primarily for anharmonicity, agree with the matrix isolation fundamentals to within an average error of about 10 per centimeter. Electron correlation is found to significantly reduce the intensities of many of the cation harmonics, bringing them into much better agreement with the available experimental data. While the theoretical infrared spectra agree well with the experimental data for the neutral systems and for many of the cations, there are notable discrepancies with the experimental matrix isolation data for some PAH cations that are difficult to explain in terms of limitations in the calculations. In agreement with previous theoretical work, the present calculations show that the relative intensities for the astronomical unidentified infrared (UIR) bands agree reasonably well with those for a distribution of polycyclic aromatic hydrocarbon (PAH) cations, but not with a distribution of PAH neutrals. We also observe that the infrared spectra of highly symmetrical cations such as coronene agree much better with astronomical observations than do those of, for example, the polyacenes such as tetracene and pentacene. The total integrated intensities for the neutral species are found to increase linearly with size, while the total integrated intensities are much larger for the cations and scale more nearly quadratically with size. We conclude that emission from moderate-sized highly symmetric PAH cations such as coronene and larger could account for the UIR bands.
Luo, Xiaoming; Cao, Juhang; He, Limin; Wang, Hongping; Yan, Haipeng; Qin, Yahua
2017-01-01
The coalescence process of binary droplets in oil under ultrasonic standing waves was investigated with high-speed photography. Three motion models of binary droplets in coalescence process were illustrated: (1) slight translational oscillation; (2) sinusoidal translational oscillation; (3) migration along with acoustic streaming. To reveal the droplets coalescence mechanisms, the influence of main factors (such as acoustic intensity, droplet size, viscosity and interfacial tension, etc) on the motion and coalescence of binary droplets was studied under ultrasonic standing waves. Results indicate that the shortest coalescence time is achieved when binary droplets show sinusoidal translational oscillation. The corresponding acoustic intensity in this case is the optimum acoustic intensity. Under the optimum acoustic intensity, drop size decrease will bring about coalescence time decrease by enhancing the binary droplets oscillation. Moreover, there is an optimum interfacial tension to achieve the shortest coalescence time. Copyright © 2016 Elsevier B.V. All rights reserved.
Analysis and testing of a new method for drop size measurement using laser scatter interferometry
NASA Technical Reports Server (NTRS)
Bachalo, W. D.; Houser, M. J.
1984-01-01
Research was conducted on a laser light scatter detection method for measuring the size and velocity of spherical particles. The method is based upon the measurement of the interference fringe pattern produced by spheres passing through the intersection of two laser beams. A theoretical analysis of the method was carried out using the geometrical optics theory. Experimental verification of the theory was obtained by using monodisperse droplet streams. Several optical configurations were tested to identify all of the parametric effects upon the size measurements. Both off-axis forward and backscatter light detection were utilized. Simulated spray environments and fuel spray nozzles were used in the evaluation of the method. The measurements of the monodisperse drops showed complete agreement with the theoretical predictions. The method was demonstrated to be independent of the beam intensity and extinction resulting from the surrounding drops. Signal processing concepts were considered and a method was selected for development.
Kumar, Vineet
2011-12-01
The grain size statistics, commonly derived from the grain map of a material sample, are important microstructure characteristics that greatly influence its properties. The grain map for nanomaterials is usually obtained manually by visual inspection of the transmission electron microscope (TEM) micrographs because automated methods do not perform satisfactorily. While the visual inspection method provides reliable results, it is a labor intensive process and is often prone to human errors. In this article, an automated grain mapping method is developed using TEM diffraction patterns. The presented method uses wide angle convergent beam diffraction in the TEM. The automated technique was applied on a platinum thin film sample to obtain the grain map and subsequently derive grain size statistics from it. The grain size statistics obtained with the automated method were found in good agreement with the visual inspection method.
Nonlinear dynamics of a vapor bubble expanding in a superheated region of finite size
DOE Office of Scientific and Technical Information (OSTI.GOV)
Annenkova, E. A., E-mail: a-a-annenkova@yandex.ru; Kreider, W.; Sapozhnikov, O. A.
2015-10-28
Growth of a vapor bubble in a superheated liquid is studied theoretically. Contrary to the typical situation of boiling, when bubbles grow in a uniformly heated liquid, here the superheated region is considered in the form of a millimeter-sized spherical hot spot. An initial micron-sized bubble is positioned at the hot spot center and a theoretical model is developed that is capable of studying bubble growth caused by vapor pressure inside the bubble and corresponding hydrodynamic and thermal processes in the surrounding liquid. Such a situation is relevant to the dynamics of vapor cavities that are created in soft biologicalmore » tissue in the focal region of a high-intensity focused ultrasound beam with a shocked pressure waveform. Such beams are used in the recently proposed treatment called boiling histotripsy. Knowing the typical behavior of vapor cavities during boiling histotripsy could help to optimize the therapeutic procedure.« less
NASA Astrophysics Data System (ADS)
Bauer, Rita A.; Kelemen, Lóránd; Nakano, Masami; Totsuka, Atsushi; Zrínyi, Miklós
2015-10-01
We have presented the first direct observation of electric field induced rotation of epoxy based polymer rotors. Polymer disks, hollow cylinders and gears were prepared in few micrometer dimensions as rotors. Electrorotation of these sub-millimeter sized tools was studied under uniform dc electric field. The effects of shape, size and thickness were investigated. The novel epoxy based micro devices show intensive spinning in a uniform dc electric field. The rotational speed of micron-sized polymer rotors can be conveniently tuned in a wide range (between 300 and 3000 rpm) by the electric field intensity, opening new perspectives for their use in several MEMS applications.
Using white-light spectroscopy for size determination of tissue phantoms
NASA Astrophysics Data System (ADS)
Vitol, Elina A.; Kurzweg, Timothy P.; Nabet, Bahram
2005-09-01
Along with breast and cervical cancer, esophageal adenocarcinoma is one of the most common types of cancers. The characteristic features of pre-cancerous tissues are the increase in cell proliferation rate and cell nuclei enlargement, which both take place in the epithelium of human body surfaces. However, in the early stages of cancer these changes are very small and difficult to detect, even for expert pathologists. The aim of our research is to develop an optical probe for in vivo detection of nuclear size changes using white light scattering from cell nuclei. The probe will be employed through an endoscope and will be used for the medical examination of the esophagus. The proposed method of examination will be noninvasive, cheap, and specific, compared to a biopsy. Before the construction of this probe, we have developed theory to determine the nuclei size from the reflection data. In this first stage of our research, we compare experimental and theoretical scattered light intensities. Our theoretical model includes the values of scatterer size from which we can extract the nuclei size value. We first performed the study of polystyrene microspheres, acting as a tissue phantom. Spectral and angular distributions of scattered white light from tissue phantoms were studied. Experimental results show significant differences between the spectra of microspheres of different sizes and demonstrate almost linear relation between the number of spectral oscillations and the size of microspheres. Best results were achieved when the scattered light spectrum was collected at 30° to the normal of the sample surface. We present these research results in this paper. In ongoing work, normal and cancerous mammalian cell studies are being performed in order to determine cell nuclei size correlation with the size of microspheres through the light scattering spectrum observation.
Deformation of olivine during phase transformation to wadsleyite
NASA Astrophysics Data System (ADS)
Mohiuddin, A.; Girard, J.; Karato, S. I.
2017-12-01
The strength of subducting slabs in the transition zone is critical in controlling the style of mantle convection. However, rheological properties of a subducted slab are elusive: low temperatures of a slab would make slabs strong, but in many regions there is evidence of intense deformation of slabs in the transition zone. One potential cause of intense deformation of subducting slabs is grain size reduction and accompanied microstructural changes during phase transformation of olivine to its higher-pressure polymorphs. There have been no experimental studies to quantify the influence of grain-size evolution. In addition to grain size reduction, distribution of small grains during phase transformation governs the degree of weakening during phase transformation (for e.g. load bearing framework vs. inter-connected layered framework). We conducted laboratory studies on the size and spatial distribution of new grains of wadsleyite after the transformation from olivine. Our results under static conditions show that an interconnected microstructure develops during the initial stage of phase transformation and that the grain size of the interconnected phase (wadsleyite) depends on the temperature at which the phase transformation occurs (smaller grains at lower temperatures). Development of an interconnected microstructure may lead to strain localization in the weaker phase, i.e. the fine-grained interconnected network accommodates most of the strain and therefore weakening of the entire composite. We will test this model through a series of two synchrotron in-situ deformation experiments: (i) Olivine aggregate will be deformed during slow pressure increase from deep upper mantle pressure ( 10 GPa) to transition zone pressure ( 15 GPa) at a given temperature simulating the deformation of a slab penetrating into the transition zone (ii) olivine is partially transformed to wadsleyite in a multi anvil apparatus at Yale and will be deformed within the stability field where olivine and wadsleyite coexist. We will use the Rotational Drickamer Apparatus (RDA) at a synchrotron facility (Argonne National Lab, 6-BM-B beamline, white beam and x-ray radiography) and characterize the stresses acting on olivine and wadsleyite during such simulations. We plan to present our preliminary results.
Nanomaterials-Based Optical Techniques for the Detection of Acetylcholinesterase and Pesticides
Xia, Ning; Wang, Qinglong; Liu, Lin
2015-01-01
The large amount of pesticide residues in the environment is a threat to global health by inhibition of acetylcholinesterase (AChE). Biosensors for inhibition of AChE have been thus developed for the detection of pesticides. In line with the rapid development of nanotechnology, nanomaterials have attracted great attention and have been intensively studied in biological analysis due to their unique chemical, physical and size properties. The aim of this review is to provide insight into nanomaterial-based optical techniques for the determination of AChE and pesticides, including colorimetric and fluorescent assays and surface plasmon resonance. PMID:25558991
Modeling Lidar Multiple Scattering
NASA Astrophysics Data System (ADS)
Sato, Kaori; Okamoto, Hajime; Ishimoto, Hiroshi
2016-06-01
A practical model to simulate multiply scattered lidar returns from inhomogeneous cloud layers are developed based on Backward Monte Carlo (BMC) simulations. The estimated time delay of the backscattered intensities returning from different vertical grids by the developed model agreed well with that directly obtained from BMC calculations. The method was applied to the Cloud-Aerosol Lidar and Infrared Pathfinder Satellite Observations (CALIPSO) satellite data to improve the synergetic retrieval of cloud microphysics with CloudSat radar data at optically thick cloud grids. Preliminary results for retrieving mass fraction of co-existing cloud particles and drizzle size particles within lowlevel clouds are demonstrated.
Progress in defect quantification in multi-layered structures using ultrasonic inspection
NASA Astrophysics Data System (ADS)
Dierken, Josiah; Aldrin, John C.; Holec, Robert; LaCivita, Michael; Shearer, Joshua; Lindgren, Eric
2013-01-01
This study investigates the ability to resolve flaws in aluminum panel stackups representative of aircraft structural components. Using immersion ultrasound techniques, the specimens were examined for known fatigue cracks and electric discharge machined (EDM) notches at various fastener sites. Initial assessments suggested a possible trend between measured ultrasound parameters of flaw intensity and size, and known physical defect length. To improve analytical reliability and efficiency, development of automated data analysis (ADA) algorithms has been initiated.
New coding technique for computer generated holograms.
NASA Technical Reports Server (NTRS)
Haskell, R. E.; Culver, B. C.
1972-01-01
A coding technique is developed for recording computer generated holograms on a computer controlled CRT in which each resolution cell contains two beam spots of equal size and equal intensity. This provides a binary hologram in which only the position of the two dots is varied from cell to cell. The amplitude associated with each resolution cell is controlled by selectively diffracting unwanted light into a higher diffraction order. The recording of the holograms is fast and simple.
Oh, Sungjin; Ahn, Jae-Hyun; Lee, Sangmin; Ko, Hyoungho; Seo, Jong Mo; Goo, Yong-Sook; Cho, Dong-il Dan
2015-01-01
Retinal prosthetic devices stimulate retinal nerve cells with electrical signals proportional to the incident light intensities. For a high-resolution retinal prosthesis, it is necessary to reduce the size of the stimulator pixels as much as possible, because the retinal nerve cells are concentrated in a small area of approximately 5 mm × 5 mm. In this paper, a miniaturized biphasic current stimulator integrated circuit is developed for subretinal stimulation and tested in vitro. The stimulator pixel is miniaturized by using a complementary metal-oxide-semiconductor (CMOS) image sensor composed of three transistors. Compared to a pixel that uses a four-transistor CMOS image sensor, this new design reduces the pixel size by 8.3%. The pixel size is further reduced by simplifying the stimulation-current generating circuit, which provides a 43.9% size reduction when compared to the design reported to be the most advanced version to date for subretinal stimulation. The proposed design is fabricated using a 0.35 μm bipolar-CMOS-DMOS process. Each pixel is designed to fit in a 50 μ m × 55 μm area, which theoretically allows implementing more than 5000 pixels in the 5 mm × 5 mm area. Experimental results show that a biphasic current in the range of 0 to 300 μA at 12 V can be generated as a function of incident light intensities. Results from in vitro experiments with rd1 mice indicate that the proposed method can be effectively used for retinal prosthesis with a high resolution.
The Merging of Fatigue and Fracture Mechanics Concepts: A Historical Perspective
NASA Technical Reports Server (NTRS)
Newman, James C., Jr.
1997-01-01
The seventh Jerry L. Swedlow Memorial Lecture presents a review of some of the technical developments, that have occurred during the past 40 years, which have led to the merger of fatigue and fracture mechanics concepts. This review is made from the viewpoint of 'crack propagation.' As methods to observe the 'fatigue' process have improved, the formation of fatigue micro-cracks have been observed earlier in life and the measured crack sizes have become smaller. These observations suggest that fatigue damage can now be characterized by 'crack size.' In parallel, the crack-growth analysis methods, using stress-intensity factors, have also improved. But the effects of material inhomogeneities, crack-fracture mechanisms, and nonlinear behavior must now be included in these analyses. The discovery of crack-closure mechanisms, such as plasticity, roughness, and oxide/corrosion/fretting product debris, and the use of the effective stress-intensity factor range, has provided an engineering tool to predict small- and large-crack-growth rate behavior under service loading, conditions. These mechanisms have also provided a rationale for developing, new, damage-tolerant materials. This review suggests that small-crack growth behavior should be viewed as typical behavior, whereas large-crack threshold behavior should be viewed as the anomaly. Small-crack theory has unified 'fatigue' and 'fracture mechanics' concepts; and has bridged the cap between safe-life and durability/damage-tolerance design concepts.
Beyond eruptive scenarios: assessing tephra fallout hazard from Neapolitan volcanoes
Sandri, Laura; Costa, Antonio; Selva, Jacopo; Tonini, Roberto; Macedonio, Giovanni; Folch, Arnau; Sulpizio, Roberto
2016-01-01
Assessment of volcanic hazards is necessary for risk mitigation. Typically, hazard assessment is based on one or a few, subjectively chosen representative eruptive scenarios, which use a specific combination of eruptive sizes and intensities to represent a particular size class of eruption. While such eruptive scenarios use a range of representative members to capture a range of eruptive sizes and intensities in order to reflect a wider size class, a scenario approach neglects to account for the intrinsic variability of volcanic eruptions, and implicitly assumes that inter-class size variability (i.e. size difference between different eruptive size classes) dominates over intra-class size variability (i.e. size difference within an eruptive size class), the latter of which is treated as negligible. So far, no quantitative study has been undertaken to verify such an assumption. Here, we adopt a novel Probabilistic Volcanic Hazard Analysis (PVHA) strategy, which accounts for intrinsic eruptive variabilities, to quantify the tephra fallout hazard in the Campania area. We compare the results of the new probabilistic approach with the classical scenario approach. The results allow for determining whether a simplified scenario approach can be considered valid, and for quantifying the bias which arises when full variability is not accounted for. PMID:27067389
Cellulose polymorphy, crystallite size, and the Segal crystallinity index
USDA-ARS?s Scientific Manuscript database
The X-ray diffraction-based Segal Crystallinity Index (CI) was calculated for simulated different sizes of crystallites for cellulose I' and II. The Mercury software was used, and different crystallite sizes were based on different input peak widths at half of the maximum peak intensity (pwhm). The ...
Relational Responding Modulates and Reverses Affective Ratings in Evaluative Conditioning
ERIC Educational Resources Information Center
Molet, Mikael; Macquet, Benjamin; Charley, Gregory
2013-01-01
Three experiments explored relational responding in evaluative conditioning. In Experiment 1, the participants were trained with a computer task to make relational responses by putting CSs of different sizes in boxes in order of size. Subsequently they were instructed that these different sized CSs represented different intensities of hypothetical…
USDA-ARS?s Scientific Manuscript database
Sprinkler drop size distribution and associated drop velocities have a major influence on sprinkler performance in regards to application intensity, uniformity of water application, wind drift, evaporation losses and kinetic energy transferred to the soil surface. Sprinkler drop size measurements a...
DOE Office of Scientific and Technical Information (OSTI.GOV)
Dai, Yang; Gorey, Timothy J.; Anderson, Scott L.
2016-12-12
X-ray absorption near-edge structure (XANES) is commonly used to probe the oxidation state of metal-containing nanomaterials, however, as the particle size in the material drops below a few nanometers, it becomes important to consider inherent size effects on the electronic structure of the materials. In this paper, we analyze a series of size-selected Pt n/SiO 2 samples, using X-ray photoelectron spectroscopy (XPS), low energy ion scattering, grazing-incidence small angle X-ray scattering, and XANES. The oxidation state and morphology are characterized both as-deposited in UHV, and after air/O 2 exposure and annealing in H 2. Here, the clusters are found tomore » be stable during deposition and upon air exposure, but sinter if heated above ~150 °C. XANES shows shifts in the Pt L 3 edge, relative to bulk Pt, that increase with decreasing cluster size, and the cluster samples show high white line intensity. Reference to bulk standards would suggest that the clusters are oxidized, however, XPS shows that they are not. Instead, the XANES effects are attributable to development of a band gap and localization of empty state wavefunctions in small clusters.« less
Probing size-dependent electrokinetics of hematite aggregates
DOE Office of Scientific and Technical Information (OSTI.GOV)
Kedra-Królik, Karolina; Rosso, Kevin M.; Zarzycki, Piotr
Aqueous particle suspensions of many kinds are stabilized by the electrostatic potential developed at their surfaces from reaction with water and ions. An important and less well understood aspect of this stabilization is the dependence of the electrostatic surface potential on particle size. Surface electrostatics are typically probed by measuring particle electrophoretic mobilities and quantified in the electrokinetic potential (f), using commercially available Zeta Potential Analyzers (ZPA). Even though ZPAs provide frequency-spectra (histograms) of electrophoretic mobility and hydrodynamic diameter, typically only the maximal-intensity values are reported, despite the information in the remainder of the spectra. Here we propose a mappingmore » procedure that inter-correlates these histograms to extract additional insight, in this case to probe particle size-dependent electrokinetics. Our method is illustrated for a suspension of prototypical iron (III) oxide (hematite, a-Fe2O3). We found that the electrophoretic mobility and f-potential are a linear function of the aggregate size. By analyzing the distribution of surface site types as a function of aggregate size we show that site coordination increases with increasing aggregate diameter. This observation explains why the acidity of the iron oxide particles decreases with increasing particle size.« less
Planning Training Workload in Football Using Small-Sided Games' Density.
Sangnier, Sebastien; Cotte, Thierry; Brachet, Olivier; Coquart, Jeremy; Tourny, Claire
2018-05-08
Sangnier, S, Cotte, T, Brachet, O, Coquart, J, and Tourny, C. Planning training workload in football using small-sided games density. J Strength Cond Res XX(X): 000-000, 2018-To develop the physical qualities, the small-sided games' (SSGs) density may be essential in soccer. Small-sided games are games in which the pitch size, players' number, and rules are different to those for traditional soccer matches. The purpose was to assess the relation between training workload and SSGs' density. The 33 densities data (41 practice games and 3 full games) were analyzed through global positioning system (GPS) data collected from 25 professional soccer players (80.7 ± 7.0 kg; 1.83 ± 0.05 m; 26.4 ± 4.9 years). From total distance, distance metabolic power, sprint distance, and acceleration distance, the data GPS were divided into 4 categories: endurance, power, speed, and strength. Statistical analysis compared the relation between GPS values and SSGs' densities, and 3 methods were applied to assess models (R-squared, root-mean-square error, and Akaike information criterion). The results suggest that all the GPS data match the player's essential athletic skills. They were all correlated with the game's density. Acceleration distance, deceleration distance, metabolic power, and total distance followed a logarithmic regression model, whereas distance and number of sprints follow a linear regression model. The research reveals options to monitor the training workload. Coaches could anticipate the load resulting from the SSGs and adjust the field size to the players' number. Taking into account the field size during SSGs enables coaches to target the most favorable density for developing expected physical qualities. Calibrating intensity during SSGs would allow coaches to assess each athletic skill in the same conditions of intensity as in the competition.
Scaling and efficiency of PRISM in adaptive simulations of turbulent premixed flames
DOE Office of Scientific and Technical Information (OSTI.GOV)
Tonse, Shaheen R.; Bell, J.B.; Brown, N.J.
1999-12-01
The dominant computational cost in modeling turbulent combustion phenomena numerically with high fidelity chemical mechanisms is the time required to solve the ordinary differential equations associated with chemical kinetics. One approach to reducing that computational cost is to develop an inexpensive surrogate model that accurately represents evolution of chemical kinetics. One such approach, PRISM, develops a polynomial representation of the chemistry evolution in a local region of chemical composition space. This representation is then stored for later use. As the computation proceeds, the chemistry evolution for other points within the same region are computed by evaluating these polynomials instead ofmore » calling an ordinary differential equation solver. If initial data for advancing the chemistry is encountered that is not in any region for which a polynomial is defined, the methodology dynamically samples that region and constructs a new representation for that region. The utility of this approach is determined by the size of the regions over which the representation provides a good approximation to the kinetics and the number of these regions that are necessary to model the subset of composition space that is active during a simulation. In this paper, we assess the PRISM methodology in the context of a turbulent premixed flame in two dimensions. We consider a range of turbulent intensities ranging from weak turbulence that has little effect on the flame to strong turbulence that tears pockets of burning fluid from the main flame. For each case, we explore a range of sizes for the local regions and determine the scaling behavior as a function of region size and turbulent intensity.« less
Light qualities and dose influence ascorbate pool size in detached oat leaves.
Mastropasqua, Linda; Borraccino, Giuseppe; Bianco, Laura; Paciolla, Costantino
2012-02-01
In this work, we studied the mechanism of light influence on AsA pool size in Avena sativa L. under the effects of low intensity light at different wavelengths. Exposure to low intensity light of oat leaf segments incubated in water or in l-galactono-1,4-lactone (GL), resulted in an increase in AsA content compared with the dark control. This increase was due to modulation of l-galactono-1,4-lactone dehydrogenase (GLDH; EC 1.3.2.3) light-dependent activity and was dependent on the size of the endogenous GL pool. Both blue and red light were effective in increasing AsA, and this increase depended on both exposure time and light intensity. Protein biosynthesis, photosynthesis and calcium were involved in controlling the level of light-dependent AsA. We suggest that multiple checkpoints correlated to the presence of light underlie the ascorbate pool size. The presence of a light-activated switch for the maintenance of an adequate AsA level seems to be necessary for the various tasks of scavenging reactive oxygen species, in response to the dark-light cycle which plants experience under natural conditions. Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.
Simple method for the characterization of intense Laguerre-Gauss vector vortex beams
NASA Astrophysics Data System (ADS)
Allahyari, E.; JJ Nivas, J.; Cardano, F.; Bruzzese, R.; Fittipaldi, R.; Marrucci, L.; Paparo, D.; Rubano, A.; Vecchione, A.; Amoruso, S.
2018-05-01
We report on a method for the characterization of intense, structured optical fields through the analysis of the size and surface structures formed inside the annular ablation crater created on the target surface. In particular, we apply the technique to laser ablation of crystalline silicon induced by femtosecond vector vortex beams. We show that a rapid direct estimate of the beam waist parameter is obtained through a measure of the crater radii. The variation of the internal and external radii of the annular crater as a function of the laser pulse energy, at fixed number of pulses, provides another way to evaluate the beam spot size through numerical fitting of the obtained experimental data points. A reliable estimate of the spot size is of paramount importance to investigate pulsed laser-induced effects on the target material. Our experimental findings offer a facile way to characterize focused, high intensity complex optical vector beams which are more and more applied in laser-matter interaction experiments.
A multidimensional stability model for predicting shallow landslide size and shape across landscapes
David G. Milledge; Dino Bellugi; Jim A. McKean; Alexander L. Densmore; William E. Dietrich
2014-01-01
The size of a shallow landslide is a fundamental control on both its hazard and geomorphic importance. Existing models are either unable to predict landslide size or are computationally intensive such that they cannot practically be applied across landscapes. We derive a model appropriate for natural slopes that is capable of predicting shallow landslide size but...
Alaverdashvili, Mariam; Paterson, Phyllis G.; Bradley, Michael P.
2015-01-01
Background The rat photothrombotic stroke model can induce brain infarcts with reasonable biological variability. Nevertheless, we observed unexplained high inter-individual variability despite using a rigorous protocol. Of the three major determinants of infarct volume, photosensitive dye concentration and illumination period were strictly controlled, whereas undetected fluctuation in laser power output was suspected to account for the variability. New method The frequently utilized Diode Pumped Solid State (DPSS) lasers emitting 532 nm (green) light can exhibit fluctuations in output power due to temperature and input power alterations. The polarization properties of the Nd:YAG and Nd:YVO4 crystals commonly used in these lasers are another potential source of fluctuation, since one means of controlling output power uses a polarizer with a variable transmission axis. Thus, the properties of DPSS lasers and the relationship between power output and infarct size were explored. Results DPSS laser beam intensity showed considerable variation. Either a polarizer or a variable neutral density filter allowed adjustment of a polarized laser beam to the desired intensity. When the beam was unpolarized, the experimenter was restricted to using a variable neutral density filter. Comparison with existing method(s) Our refined approach includes continuous monitoring of DPSS laser intensity via beam sampling using a pellicle beamsplitter and photodiode sensor. This guarantees the desired beam intensity at the targeted brain area during stroke induction, with the intensity controlled either through a polarizer or variable neutral density filter. Conclusions Continuous monitoring and control of laser beam intensity is critical for ensuring consistent infarct size. PMID:25840363
NASA Astrophysics Data System (ADS)
Park, Kyungjeen
This study aims to develop an objective hurricane initialization scheme which incorporates not only forecast model constraints but also observed features such as the initial intensity and size. It is based on the four-dimensional variational (4D-Var) bogus data assimilation (BDA) scheme originally proposed by Zou and Xiao (1999). The 4D-Var BDA consists of two steps: (i) specifying a bogus sea level pressure (SLP) field based on parameters observed by the Tropical Prediction Center (TPC) and (ii) assimilating the bogus SLP field under a forecast model constraint to adjust all model variables. This research focuses on improving the specification of the bogus SLP indicated in the first step. Numerical experiments are carried out for Hurricane Bonnie (1998) and Hurricane Gordon (2000) to test the sensitivity of hurricane track and intensity forecasts to specification of initial vortex. Major results are listed below: (1) A linear regression model is developed for determining the size of initial vortex based on the TPC observed radius of 34kt. (2) A method is proposed to derive a radial profile of SLP from QuikSCAT surface winds. This profile is shown to be more realistic than ideal profiles derived from Fujita's and Holland's formulae. (3) It is found that it takes about 1 h for hurricane prediction model to develop a conceptually correct hurricane structure, featuring a dominant role of hydrostatic balance at the initial time and a dynamic adjustment in less than 30 minutes. (4) Numerical experiments suggest that track prediction is less sensitive to the specification of initial vortex structure than intensity forecast. (5) Hurricane initialization using QuikSCAT-derived initial vortex produced a reasonably good forecast for hurricane landfall, with a position error of 25 km and a 4-h delay at landfalling. (6) Numerical experiments using the linear regression model for the size specification considerably outperforms all the other formulations tested in terms of the intensity prediction for both Hurricanes. For examples, the maximum track error is less than 110 km during the entire three-day forecasts for both hurricanes. The simulated Hurricane Gordon using the linear regression model made a nearly perfect landfall, with no position error and only 1-h error in landfalling time. (7) Diagnosis of model output indicates that the initial vortex specified by the linear regression model produces larger surface fluxes of sensible heat, latent heat and moisture, as well as stronger downward angular momentum transport than all the other schemes do. These enhanced energy supplies offset the energy lost caused by friction and gravity wave propagation, allowing for the model to maintain a strong and realistic hurricane during the entire forward model integration.
NASA Technical Reports Server (NTRS)
Dekany, Justin; Christensen, Justin; Dennison, J. R.; Jensen, Amberly Evans; Wilson, Gregory; Schneider, Todd; Bowers, Charles W.; Meloy, Robert
2015-01-01
Many contemporary spacecraft materials exhibit cathodoluminescence when exposed to electron flux from the space plasma environment. A quantitative, physics-based model has been developed to predict the intensity of the total glow as a function of incident electron current density and energy, temperature, and intrinsic material properties. We present a comparative study of the absolute spectral radiance for more than 20 types of dielectric and composite materials based on this model which spans more than three orders of magnitude. Variations in intensity are contrasted for different electron environments, different sizes of samples and sample sets, different testing and analysis methods, and data acquired at different test facilities. Together, these results allow us to estimate the accuracy and precision to which laboratory studies may be able to determine the response of spacecraft materials in the actual space environment. It also provides guidance as to the distribution of emissions that may be expected for sets of similar flight hardware under similar environmental conditions.
NASA Technical Reports Server (NTRS)
Dekany, Justin; Christensen, Justin; Dennison, J. R.; Jensen, Amberly Evans; Wilson, Gregory; Schneider, Todd A.; Bowers, Charles W.; Meloy, Robert
2014-01-01
Many contemporary spacecraft materials exhibit cathodoluminescence when exposed to electron flux from the space plasma environment. A quantitative, physics-based model has been developed to predict the intensity of the glow as a function of incident electron current density and energy, temperature, and intrinsic material properties. We present a comparative study of the absolute spectral radiance for several types of dielectric and composite materials based on this model which spans three orders of magnitude. Variations in intensity are contrasted for different electron environments, different sizes of samples and sample sets, different testing and analysis methods, and data acquired at different test facilities. Together, these results allow us to estimate the accuracy and precision to which laboratory studies may be able to determine the response of spacecraft materials in the actual space environment. It also provides guidance as to the distribution of emissions that may be expected for sets of similar flight hardware under similar environmental conditions.
Spatiotemporal Fluctuations and Triggers of Ebola Virus Spillover
Park, Andrew W.; Kramer, Andrew M.; Han, Barbara A.; Alexander, Laura W.; Drake, John M.
2017-01-01
Because the natural reservoir of Ebola virus remains unclear and disease outbreaks in humans have occurred only sporadically over a large region, forecasting when and where Ebola spillovers are most likely to occur constitutes a continuing and urgent public health challenge. We developed a statistical modeling approach that associates 37 human or great ape Ebola spillovers since 1982 with spatiotemporally dynamic covariates including vegetative cover, human population size, and absolute and relative rainfall over 3 decades across sub-Saharan Africa. Our model (area under the curve 0.80 on test data) shows that spillover intensity is highest during transitions between wet and dry seasons; overall, high seasonal intensity occurs over much of tropical Africa; and spillover intensity is greatest at high (>1,000/km2) and very low (<100/km2) human population densities compared with intermediate levels. These results suggest strong seasonality in Ebola spillover from wild reservoirs and indicate particular times and regions for targeted surveillance. PMID:28221131
Analysis of surface cracks in finite plates under tension or bending loads
NASA Technical Reports Server (NTRS)
Newman, J. C., Jr.; Raju, I. S.
1979-01-01
Stress-intensity factors calculated with a three-dimensional, finite-element analysis for shallow and deep semielliptical surface cracks in finite elastic isotropic plates subjected to tension or bending loads are presented. A wide range of configuration parameters was investigated. The ratio of crack depth to plate thickness ranged from 0.2 to 0.8 and the ratio of crack depth to crack length ranged from 0.2 to 2.0. The effects of plate width on stress-intensity variations along the crack front was also investigated. A wide-range equation for stress-intensity factors along the crack front as a function of crack depth, crack length, plate thickness, and plate width was developed for tension and bending loads. The equation was used to predict patterns of surface-crack growth under tension or bending fatigue loads. A modified form of the equation was also used to correlate surface-crack fracture data for a brittle epoxy material within + or - 10 percent for a wide range of crack shapes and crack sizes.
Short intense ion pulses for materials and warm dense matter research
NASA Astrophysics Data System (ADS)
Seidl, Peter A.; Persaud, Arun; Waldron, William L.; Barnard, John J.; Davidson, Ronald C.; Friedman, Alex; Gilson, Erik P.; Greenway, Wayne G.; Grote, David P.; Kaganovich, Igor D.; Lidia, Steven M.; Stettler, Matthew; Takakuwa, Jeffrey H.; Schenkel, Thomas
2015-11-01
We have commenced experiments with intense short pulses of ion beams on the Neutralized Drift Compression Experiment-II at Lawrence Berkeley National Laboratory, by generating beam spots size with radius r<1 mm within 2 ns FWHM and approximately 1010 ions/pulse. To enable the short pulse durations and mm-scale focal spot radii, the 1.2 MeV Li+ ion beam is neutralized in a 1.6-meter drift compression section located after the last accelerator magnet. An 8-Tesla short focal length solenoid compresses the beam in the presence of the large volume plasma near the end of this section before the target. The scientific topics to be explored are warm dense matter, the dynamics of radiation damage in materials, and intense beam and beam-plasma physics including selected topics of relevance to the development of heavy-ion drivers for inertial fusion energy. Here we describe the accelerator commissioning and time-resolved ionoluminescence measurements of yttrium aluminum perovskite using the fully integrated accelerator and neutralized drift compression components.
Pan, Yong-Le; Hill, Steven C; Coleman, Mark
2012-02-27
A new method is demonstrated for optically trapping micron-sized absorbing particles in air and obtaining their single-particle Raman spectra. A 488-nm Gaussian beam from an Argon ion laser is transformed by conical lenses (axicons) and other optics into two counter-propagating hollow beams, which are then focused tightly to form hollow conical beams near the trapping region. The combination of the two coaxial conical beams, with focal points shifted relative to each other along the axis of the beams, generates a low-light-intensity biconical region totally enclosed by the high-intensity light at the surface of the bicone, which is a type of bottle beam. Particles within this region are trapped by the photophoretic forces that push particles toward the low-intensity center of this region. Raman spectra from individual trapped particles made from carbon nanotubes are measured. This trapping technique could lead to the development of an on-line real-time single-particle Raman spectrometer for characterization of absorbing aerosol particles.
Normal and radial impact of composites with embedded penny-shaped cracks
NASA Technical Reports Server (NTRS)
Sih, G. C.
1979-01-01
A method is developed for the dynamic stress analysis of a layered composite containing an embedded penny-shaped crack and subjected to normal and radial impact. The material properties of the layers are chosen such that the crack lies in a layer of matrix material while the surrounding material possesses the average elastic properties of a two-phase medium consisting of a large number of fibers embedded in the matrix. Quantitatively, the time-dependent stresses near the crack border can be described by the dynamic stress intensity factors. Their magnitude depends on time, on the material properties of the composite and on the relative size of the crack compared to the composite local geometry. Results obtained show that, for the same material properties and geometry of the composite, the dynamic stress intensity factors for an embedded (penny-shaped) crack reach their peak values within a shorter period of time and with a lower magnitude than the corresponding dynamic stress intensity factors for a through-crack.
NASA Astrophysics Data System (ADS)
Liu, Ming-Ping; Liu, Bing-Bing; Liu, San-Qiu; Zhang, Fu-Yang; Liu, Jie
2013-08-01
Using a variational approach, the propagation of a moderately intense laser pulse in a parabolic preformed plasma channel is investigated. The effects of higher-order relativistic nonlinearity (HRN) and wakefield are included. The effect of HRN serves as an additional defocusing mechanism and has the same order of magnitude in the spot size as that of the transverse wakefield (TWF). The effect of longitudinal wakefield is much larger than those of HRN and TWF for an intense laser pulse with the pulse length equaling the plasma wavelength. The catastrophic focusing of the laser spot size would be prevented in the present of HRN and then it varies with periodic focusing oscillations.
Analytical solutions to trade-offs between size of protected areas and land-use intensity.
Butsic, Van; Radeloff, Volker C; Kuemmerle, Tobias; Pidgeon, Anna M
2012-10-01
Land-use change is affecting Earth's capacity to support both wild species and a growing human population. The question is how best to manage landscapes for both species conservation and economic output. If large areas are protected to conserve species richness, then the unprotected areas must be used more intensively. Likewise, low-intensity use leaves less area protected but may allow wild species to persist in areas that are used for market purposes. This dilemma is present in policy debates on agriculture, housing, and forestry. Our goal was to develop a theoretical model to evaluate which land-use strategy maximizes economic output while maintaining species richness. Our theoretical model extends previous analytical models by allowing land-use intensity on unprotected land to influence species richness in protected areas. We devised general models in which species richness (with modified species-area curves) and economic output (a Cobb-Douglas production function) are a function of land-use intensity and the proportion of land protected. Economic output increased as land-use intensity and extent increased, and species richness responded to increased intensity either negatively or following the intermediate disturbance hypothesis. We solved the model analytically to identify the combination of land-use intensity and protected area that provided the maximum amount of economic output, given a target level of species richness. The land-use strategy that maximized economic output while maintaining species richness depended jointly on the response of species richness to land-use intensity and protection and the effect of land use outside protected areas on species richness within protected areas. Regardless of the land-use strategy, species richness tended to respond to changing land-use intensity and extent in a highly nonlinear fashion. ©2012 Society for Conservation Biology.
Development and performance evaluation of air fine bubbles on water quality of thai catfish rearing
NASA Astrophysics Data System (ADS)
Subhan, Ujang; Muthukannan, Vanitha; Azhary, Sundoro Yoga; Mulhadi, Muhammad Fakhri; Rochima, Emma; Panatarani, Camellia; Joni, I. Made
2018-02-01
The efficiency and productivity of aquaculture strongly depends on the development of advanced technology for water quality management system. The most important factor for the success of intensive aquaculture system is controlling the water quality of fish rearing media. This paper reports the design of fine bubbles (FBs) generator and performance evaluation of the system to improve water quality in thai catfish media (10 g/ind) with density (16.66 ind./L). The FBs generator was designed to control the size distribution of bubble by controlling its air flow rate entry to the mixing chamber of the generator. The performance of the system was evaluated based on the produced debit, dissolved oxygen rate and ammonia content in the catfish medium. The size distribution was observed by using a high speed camera image followed by processing using ImageJ. freeware application. The results show that air flow rate 0.05 L/min and 0.1 L/min received average bubble size of 29 µm and 31 µm respectively. The generator produced bubbles with capacity of 6 L/min and dissolved oxygen rate 0.2 ppm/min/L. The obtained DO growth was 0.455 ppm/second/L while the average decay rate was 0.20 ppm/second/L. (0.011/0.005 fold). In contrast, the recieved DO growth rate is faster compared to the DO consumption rate of the Thai catfish. This results indicated that the potential application of FBs enhanced the density of thai catfish seed rearing. In addition, ammonia can be reduced at 0.0358 ppm/hour/L and it is also observed that the inhibition of bacterial growth of air FBs is postive to Aeromonas hydrophila bacteria compared to the negative control. It is concluded that as-developed FBs system can be potentially applied for intensive thai catfish culture and expected to improve the feeding efficiency rate.
Analytical coupled-wave model for photonic crystal surface-emitting quantum cascade lasers.
Wang, Zhixin; Liang, Yong; Yin, Xuefan; Peng, Chao; Hu, Weiwei; Faist, Jérôme
2017-05-15
An analytical coupled-wave model is developed for surface-emitting photonic-crystal quantum cascade lasers (PhC-QCLs). This model provides an accurate and efficient analysis of full three-dimensional device structure with large-area cavity size. Various laser properties of interest including the band structure, mode frequency, cavity loss, mode intensity profile, and far field pattern (FFP), as well as their dependence on PhC structures and cavity size, are investigated. Comparison with numerical simulations confirms the accuracy and validity of our model. The calculated FFP and polarization profile well explain the previously reported experimental results. In particular, we reveal the possibility of switching the lasing modes and generating single-lobed FFP by properly tuning PhC structures.
Ward, Nicholas S; Read, Richard; Afessa, Bekele; Kahn, Jeremy M
2012-02-01
Increases in the size and number of American intensive care units have not been accompanied by a comparable increase in the critical care physician workforce, raising concerns that intensivists are becoming overburdened by workload. This is especially concerning in academic intensive care units where attending physicians must couple teaching duties with patient care. We performed an in-person and electronic survey of the membership of the Association of Pulmonary and Critical Care Medicine Program Directors, soliciting information about patient workload, other hospital and medical education duties, and perceptions of the workplace and teaching environment of their intensive care units. Eighty-four out of a total 121 possible responses were received from program directors or their delegates, resulting in a response rate of 69%. The average daily (SD) census (as perceived by the respondents) was 18.8 ± 8.9 patients, and average (SD) maximum service size recalled was 24.1 ± 9.9 patients. Twenty-seven percent reported no policy setting an upper limit for the daily census. Twenty-eight percent of respondents felt the average census was "too many" and 71% felt the maximum size was "too many." The median (interquartile range) patient-to-attending physician ratio was 13 (10-16). When categorized according to this median, respondents from intensive care units with high patient/physician ratios (n = 31) perceived significantly more time constraints, more stress, and difficulties with teaching trainees than respondents with low patient/physician ratios (n = 40). The total number of non-nursing healthcare workers per patient was similar in both groups, suggesting that having more nonattending physician staff does not alleviate perceptions of overwork and stress in the attending physician. Academic intensive care unit physicians that direct fellowship programs frequently perceived being overburdened in the intensive care unit. Understaffing intensive care units with attending physicians may have a negative impact on teaching, patient care, and workforce stability.
Mekonnen, Zeleke; Meka, Selima; Ayana, Mio; Bogers, Johannes; Vercruysse, Jozef; Levecke, Bruno
2013-01-01
Background In veterinary parasitology samples are often pooled for a rapid assessment of infection intensity and drug efficacy. Currently, studies evaluating this strategy in large-scale drug administration programs to control human soil-transmitted helminths (STHs; Ascaris lumbricoides, Trichuris trichiura, and hookworm), are absent. Therefore, we developed and evaluated a pooling strategy to assess intensity of STH infections and drug efficacy. Methods/Principal Findings Stool samples from 840 children attending 14 primary schools in Jimma, Ethiopia were pooled (pool sizes of 10, 20, and 60) to evaluate the infection intensity of STHs. In addition, the efficacy of a single dose of mebendazole (500 mg) in terms of fecal egg count reduction (FECR; synonym of egg reduction rate) was evaluated in 600 children from two of these schools. Individual and pooled samples were examined with the McMaster egg counting method. For each of the three STHs, we found a significant positive correlation between mean fecal egg counts (FECs) of individual stool samples and FEC of pooled stool samples, ranging from 0.62 to 0.98. Only for A. lumbricoides was any significant difference in mean FEC of the individual and pooled samples found. For this STH species, pools of 60 samples resulted in significantly higher FECs. FECR for the different number of samples pooled was comparable in all pool sizes, except for hookworm. For this parasite, pools of 10 and 60 samples provided significantly higher FECR results. Conclusion/Significance This study highlights that pooling stool samples holds promise as a strategy for rapidly assessing infection intensity and efficacy of administered drugs in programs to control human STHs. However, further research is required to determine when and how pooling of stool samples can be cost-effectively applied along a control program, and to verify whether this approach is also applicable to other NTDs. PMID:23696905
Optical Multi-Channel Intensity Interferometry - Or: How to Resolve O-Stars in the Magellanic Clouds
NASA Astrophysics Data System (ADS)
Trippe, Sascha; Kim, Jae-Young; Lee, Bangwon; Choi, Changsu; Oh, Junghwan; Lee, Taeseok; Yoon, Sung-Chul; Im, Myungshin; Park, Yong-Sun
2014-12-01
Intensity interferometry, based on the Hanbury Brown--Twiss effect, is a simple and inexpensive method for optical interferometry at microarcsecond angular resolutions; its use in astronomy was abandoned in the 1970s because of low sensitivity. Motivated by recent technical developments, we argue that the sensitivity of large modern intensity interferometers can be improved by factors up to approximately 25,000, corresponding to 11 photometric magnitudes, compared to the pioneering Narrabri Stellar Interferometer. This is made possible by (i) using avalanche photodiodes (APD) as light detectors, (ii) distributing the light received from the source over multiple independent spectral channels, and (iii) use of arrays composed of multiple large light collectors. Our approach permits the construction of large (with baselines ranging from few kilometers to intercontinental distances) optical interferometers at the cost of (very) long-baseline radio interferometers. Realistic intensity interferometer designs are able to achieve limiting R-band magnitudes as good as m_R≈14, sufficient for spatially resolved observations of main-sequence O-type stars in the Magellanic Clouds. Multi-channel intensity interferometers can address a wide variety of science cases: (i) linear radii, effective temperatures, and luminosities of stars, via direct measurements of stellar angular sizes; (ii) mass--radius relationships of compact stellar remnants, via direct measurements of the angular sizes of white dwarfs; (iii) stellar rotation, via observations of rotation flattening and surface gravity darkening; (iv) stellar convection and the interaction of stellar photospheres and magnetic fields, via observations of dark and bright starspots; (v) the structure and evolution of multiple stars, via mapping of the companion stars and of accretion flows in interacting binaries; (vi) direct measurements of interstellar distances, derived from angular diameters of stars or via the interferometric Baade--Wesselink method; (vii) the physics of gas accretion onto supermassive black holes, via resolved observations of the central engines of luminous active galactic nuclei; and (viii) calibration of amplitude interferometers by providing a sample of calibrator stars.
USDA-ARS?s Scientific Manuscript database
The Segal method estimates the amorphous fraction of cellulose IB materials simply based on intensity at 18o 20 in an X-ray diffraction pattern and was extended to cellulose II using 16o 2O intensity. To address the dependency of Segal amorphous intensity on crystal size, cellulose polymorph, and th...
Study of fracture toughness of ZrO2 ceramics
NASA Astrophysics Data System (ADS)
Deryugin, Yevgeny; Narkevich, Natalya; Vlasov, Ilya; Panin, Victor; Danilenko, Igor; Schmauder, Siegfried
2017-12-01
The fracture toughness characteristics of ZrO2ceramics were determined experimentally using an original technique of wedging small-sized chevron notch specimens developed at the Institute of Strength Physics and Materials Science SB RAS (Russia) in the laboratory of physical mesomechanics of materials and non-destructive testing. Measurements have shown that inelastic displacements can be more than 22% of the total displacement of the consoles by the time of the specimen failure. The effect of the Y2O3 stabilizer on the critical stress intensity factor KIc was verified. It was shown that an increase in the Y2O3 stabilizer content from 3 to 8% significantly decreases the fracture toughness. The stress intensity factor KIc falls within the range from 5.7 to 2.35 MPa m1/2.
NASA Technical Reports Server (NTRS)
Thomas, P. G.; Gierasch, P.
1985-01-01
Large columns of dust have been discovered rising above plains on Mars. The storms are probably analogous to terrestrial dust devils, but their size indicates that they are more similar to tornadoes in intensity. They occur at locations where the soil has been strongly warmed by the Sun, and there the surface is smooth and fine grained. These are the same conditions that favor dust devils on Earth. Warm gas from the lowest atmospheric layer converges and rises in a thin column, with intense swirl developing at the edge of the column. In one area a mosaic of Viking images shows 97 vortices in a three day period. This represents a density of vortices of about one in each 900 square kilometers. Thus, these dust devils may be important in moving dust or starting over dust storms.
High-intensity laser-accelerated ion beam produced from cryogenic micro-jet target
Gauthier, M.; Kim, J. B.; Curry, C. B.; ...
2016-08-24
Here, we report on the successful operation of a newly developed cryogenic jet target at high intensity laser-irradiation. Using the frequency-doubled Titan short pulse laser system at Jupiter Laser Facility, Lawrence Livermore National Laboratory, we demonstrate the generation of a pure proton beam a with maximum energy of 2 MeV. Furthermore, we record a quasi-monoenergetic peak at 1.1 MeV in the proton spectrum emitted in the laser forward direction suggesting an alternative acceleration mechanism. Using a solid-density mixed hydrogen-deuterium target, we are also able to produce pure proton-deuteron ion beams. With its high purity, limited size, near-critical density, and high-repetitionmore » rate capability, this target is promising for future applications.« less
High-intensity laser-accelerated ion beam produced from cryogenic micro-jet target
DOE Office of Scientific and Technical Information (OSTI.GOV)
Gauthier, M., E-mail: maxence.gauthier@stanford.edu; Kim, J. B.; Curry, C. B.
2016-11-15
We report on the successful operation of a newly developed cryogenic jet target at high intensity laser-irradiation. Using the frequency-doubled Titan short pulse laser system at Jupiter Laser Facility, Lawrence Livermore National Laboratory, we demonstrate the generation of a pure proton beam a with maximum energy of 2 MeV. Furthermore, we record a quasi-monoenergetic peak at 1.1 MeV in the proton spectrum emitted in the laser forward direction suggesting an alternative acceleration mechanism. Using a solid-density mixed hydrogen-deuterium target, we are also able to produce pure proton-deuteron ion beams. With its high purity, limited size, near-critical density, and high-repetition ratemore » capability, this target is promising for future applications.« less
NASA Technical Reports Server (NTRS)
Sih, G. C.; Chen, E. P.
1980-01-01
A method is developed for the dynamic stress analysis of a layered composite containing an embedded penny-shaped crack and subjected to normal and radial impact. Quantitatively, the time-dependent stresses near the crack border can be described by the dynamic stress intensity factors. Their magnitude depends on time, on the material properties of the composite and on the relative size of the crack compared to the composite local geometry. Results obtained show that, for the same material properties and geometry of the composite, the dynamic stress intensity factors for an embedded (penny-shaped) crack reach their peak values within a shorter period of time and with a lower magnitude than the corresponding dynamic stress factors for a through-crack.
New non-linear photovoltaic effect in uniform bipolar semiconductor
DOE Office of Scientific and Technical Information (OSTI.GOV)
Volovichev, I.
2014-11-21
A linear theory of the new non-linear photovoltaic effect in the closed circuit consisting of a non-uniformly illuminated uniform bipolar semiconductor with neutral impurities is developed. The non-uniform photo-excitation of impurities results in the position-dependant current carrier mobility that breaks the semiconductor homogeneity and induces the photo-electromotive force (emf). As both the electron (or hole) mobility gradient and the current carrier generation rate depend on the light intensity, the photo-emf and the short-circuit current prove to be non-linear functions of the incident light intensity at an arbitrarily low illumination. The influence of the sample size on the photovoltaic effect magnitudemore » is studied. Physical relations and distinctions between the considered effect and the Dember and bulk photovoltaic effects are also discussed.« less
Fiber optic light-scattering measurement system for evaluation of embryo viability: model experiment
NASA Astrophysics Data System (ADS)
Itoh, Harumi; Arai, Tsunenori; Kikuchi, Makoto
1996-05-01
We evaluated the particle density detectability and particle size detectivity of our fiber-optic light-scattering measurement system. In order to prevent the multiple pregnancy on current in vitro fertilization-embryo transfer, we have aimed to develop a new quantitative and non- invasive method to select a single viable human embryo. We employed the measurement of mitochondria localization in an embryo, which may have the correlation with development ability. We applied the angular distribution measurement of the light-scattering intensity from the embryo to obtain the information originated from the mitochondria. The latex spheres with a diameter of 1.0 micrometers were used to simulate the scattering intensity of the mitochondria. The measurement probes of our system consisted of two fibers for illumination and sensing. They were arranged at a right angle to a microscope optical axis to measure the angular distribution of the light-scattering intensity. We observed that the light-scattering intensity increased monotonically in the range from 106 to 1010 particles per ml. Since the mitochondria density in a human embryo corresponded to 2.5 X 107 per ml in the measurement chamber, we may measure the mitochondria density in the human embryo. The angular dependence of light-scattering intensity changed with the sphere diameters. This result showed the possibility of the selective measurement of the mitochondria density in the embryo in spite of the presence of the other cell organelle. We think that our light-scattering measurement system might be applicable to the evaluation method for the embryo viability.
Numerical Study of the Influences of a Monsoon Gyre on Intensity Changes of Typhoon Chan-Hom (2015)
NASA Astrophysics Data System (ADS)
Liang, Jia; Wu, Liguang; Gu, Guojun
2018-05-01
Typhoon Chan-Hom (2015) underwent a weakening in the tropical western North Pacific (WNP) when it interacted with a monsoon gyre, but all operational forecasts failed to predict this intensity change. A recent observational study indicated that it resulted from its interaction with a monsoon gyre on the 15-30-day timescale. In this study, the results of two numerical experiments are presented to investigate the influence of the monsoon gyre on the intensity changes of Typhoon Chan-Hom (2015). The control experiment captures the main observed features of the weakening process of Chan-Hom (2015) during a sharp northward turn in the Philippine Sea, including the enlargement of the eye size, the development of strong convection on the eastern side of the monsoon gyre, and the corresponding strong outer inflow. The sensitivity experiment suggests that intensity changes of Chan-Hom (2015) were mainly associated with its interaction with the monsoon gyre. When Chan-Hom (2015) initially moved westward in the eastern part of the monsoon gyre, the monsoon gyre enhanced the inertial stability for the intensification of the typhoon. With its coalescence with the monsoon gyre, the development of the strong convection on the eastern side of the monsoon gyre prevented moisture and mass entering the inner core of Chan-Hom (2015), resulting in the collapse of the eyewall. Thus, the weakening happened in the deep tropical WNP region. The numerical simulations confirm the important effects of the interaction between tropical cyclones and monsoon gyres on tropical cyclone intensity.
Optical countermeasures against CLOS weapon systems
NASA Astrophysics Data System (ADS)
Toet, Alexander; Benoist, Koen W.; van Lingen, Joost N. J.; Schleijpen, H. Ric M. A.
2013-10-01
There are many weapon systems in which a human operator acquires a target, tracks it and designates it. Optical countermeasures against this type of systems deny the operator the possibility to fulfill this visual task. We describe the different effects that result from stimulation of the human visual system with high intensity (visible) light, and the associated potential operational impact. Of practical use are flash blindness, where an intense flash of light produces a temporary "blind-spot" in (part of) the visual field, flicker distraction, where strong intensity and/or color changes at a discomfortable frequency are produced, and disability glare where a source of light leads to contrast reduction. Hence there are three possibilities to disrupt the visual task of an operator with optical countermeasures such as flares or lasers or a combination of these; namely, by an intense flash of light, by an annoying light flicker or by a glare source. A variety of flares for this purpose is now available or under development: high intensity flash flares, continuous burning flares or strobe flares which have an oscillating intensity. The use of flare arrays seems particularly promising as an optical countermeasure. Lasers are particularly suited to interfere with human vision, because they can easily be varied in intensity, color and size, but they have to be directed at the (human) target, and issues like pointing and eye-safety have to be taken into account. Here we discuss the design issues and the operational impact of optical countermeasures against human operators.
Tagliolatto, Alícia Bertoloto; Guimarães, Suzana Machado; Lobo-Hajdu, Gisele; Monteiro-Neto, Cassiano
2016-10-27
Fibropapillomatosis (FP) is a multifactorial disease that affects all species of marine turtles, including green turtles Chelonia mydas (Linnaeus, 1758). It is characterised by the development of internal or external tumours that, depending on their locations and sizes, may intensely impact the health condition of sea turtles. The goal of this study was to characterise the disease in C. mydas found in a foraging area in southeastern Brazil, evaluate the prevalence in this region, and correlate presence and absence, size, body distribution, number of tumours, and disease severity with biometric variables of the captured green turtles. Between 2008 and 2014, the prevalence rate of FP was 43.09%, out of 246 green turtles. The size of the animals with FP was relatively greater than animals without tumours, and the prevalence of FP increased with animal size, peaking in the 60-80 cm size class. From 2013 to 2014, gross evaluation of fibropapillomas was performed. The number of tumours per turtle ranged from 1 to 158. The size of tumours ranged from <1 cm (Size A) to >10 cm (Size D); Size A tumours and turtles slightly affected by the disease (Score 1) predominated. Tumour progression (72.1%) and regression (32.8%) were seen in some recaptured individuals (n = 61). Moreover, 24.6% of these turtles showed both progressions and regressions of tumours.
McDonald, Linda S; Panozzo, Joseph F; Salisbury, Phillip A; Ford, Rebecca
2016-01-01
Field peas (Pisum sativum L.) are generally traded based on seed appearance, which subjectively defines broad market-grades. In this study, we developed an objective Linear Discriminant Analysis (LDA) model to classify market grades of field peas based on seed colour, shape and size traits extracted from digital images. Seeds were imaged in a high-throughput system consisting of a camera and laser positioned over a conveyor belt. Six colour intensity digital images were captured (under 405, 470, 530, 590, 660 and 850nm light) for each seed, and surface height was measured at each pixel by laser. Colour, shape and size traits were compiled across all seed in each sample to determine the median trait values. Defective and non-defective seed samples were used to calibrate and validate the model. Colour components were sufficient to correctly classify all non-defective seed samples into correct market grades. Defective samples required a combination of colour, shape and size traits to achieve 87% and 77% accuracy in market grade classification of calibration and validation sample-sets respectively. Following these results, we used the same colour, shape and size traits to develop an LDA model which correctly classified over 97% of all validation samples as defective or non-defective.
McDonald, Linda S.; Panozzo, Joseph F.; Salisbury, Phillip A.; Ford, Rebecca
2016-01-01
Field peas (Pisum sativum L.) are generally traded based on seed appearance, which subjectively defines broad market-grades. In this study, we developed an objective Linear Discriminant Analysis (LDA) model to classify market grades of field peas based on seed colour, shape and size traits extracted from digital images. Seeds were imaged in a high-throughput system consisting of a camera and laser positioned over a conveyor belt. Six colour intensity digital images were captured (under 405, 470, 530, 590, 660 and 850nm light) for each seed, and surface height was measured at each pixel by laser. Colour, shape and size traits were compiled across all seed in each sample to determine the median trait values. Defective and non-defective seed samples were used to calibrate and validate the model. Colour components were sufficient to correctly classify all non-defective seed samples into correct market grades. Defective samples required a combination of colour, shape and size traits to achieve 87% and 77% accuracy in market grade classification of calibration and validation sample-sets respectively. Following these results, we used the same colour, shape and size traits to develop an LDA model which correctly classified over 97% of all validation samples as defective or non-defective. PMID:27176469
DOE Office of Scientific and Technical Information (OSTI.GOV)
Coughlan, H. D.; Darmanin, C.; Kirkwood, H. J.
2016-03-14
Three-dimensional imaging of protein crystals during X-ray diffraction experiments opens up a range of possibilities for optimising crystal quality and gaining new insights into the fundamental processes that drive radiation damage. Obtaining this information at the appropriate lengthscales however is extremely challenging. One approach that has been recently demonstrated as a promising avenue for charactering the size and shape of protein crystals at nanometre lengthscales is Bragg Coherent Diffractive Imaging (BCDI). BCDI is a recently developed technique that is able to recover the phase of the continuous diffraction intensity signal around individual Bragg peaks. When data is collected at multiplemore » points on a rocking curve a Reciprocal Space Map (RSM) can be assembled and then inverted using BCDI to obtain a three-dimensional image of the crystal. The first demonstration of two-dimensional BCDI of protein crystals was reported by Boutet at al., recently this work was extended to the study of radiation damage of micron-sized crystals. Here we present the first three-dimensional reconstructions of a Lysozyme protein crystal using BDI. The results are validated against RSM and TEM data and have implications for both radiation damage studies and for developing new approaches to structure retrieval from micron-sized protein crystals.« less
Characterization of CVD micrometer-size diamond (abstract)
NASA Astrophysics Data System (ADS)
Ohsumi, K.; Hagiya, K.; Miyamoto, M.; Matsuda, J.; Ohmasa, M.
1989-07-01
In the field of material sciences, it has long been desired to develope the equipment to obtain crystallographic information of micrometer-size crystalline substances. Synchrotron radiation (SR) could be a candidate to deal with such a small specimen other than electron microscope. It seems more advantageous to utilize SR from the viewpoint that the processing of the diffraction data that has already been established for identification of the materials, structure analysis, and refinement. Even in the case of SR, special care should be taken for the measurement of very weak diffracted intensities. In the case not using SR, the size of 50 μm might be the limit for the specimen to be examined by the diffraction method. The diffracted intensity is proportional to the volume of the specimen, and that of micrometer-size crystal is estimated as 10-5 times of that of the limit mentioned above. The noise level of the experiment, therefore, should be as low as possible. If the noise level becomes negligibly small, the signal could be accumulated continually to the desired intensity level by adjusting measuring time. The experiment, for the purpose, should be carried out in vacuum with the stational crystal method and with very narrow collimated x-ray beams. The Laue method is employed by the above reason, as well as the fact that the intensity of each Bragg reflection on a reciprocal row passing through the origin of the reciprocal space is superposed with each other, which also intensifies a diffraction spot on the photographic plate. The Laue camera is set up at BL-4B of Photon Factory, sealed in vacuum and installed with a very narrow collimater. The development of the system has been performed to the level which several Bragg reflections of molybdenum single crystal with 0.8 μm in its diameter can be taken on the imaging plate for 50-min exposure with ring current from 128 to 125 mA. The origin of diamonds in meteorites has been a controversy as to whether they are formed from carbonaceous materials by impact shock or directly formed from vapor. Recent discovery of vapor-growth diamonds in carbonaceous chondrites has generated a renewed interest in the origin of ureilite diamonds. Two types of micrometer-size diamonds were prepared. One of them was grown under low pressure by chemical vapor deposition (CVD) from gaseous mixtures of H2 and CH4, and another was synthesized by shock effect (kindly offered by Nippon Oil & Fats Co., Ltd.) The micro-Laue method was applied to them in order to get information about their microstructures. Two characteristics are recognized in profiles of reflections themselves and in whole patterns of the Laue photographs. The reflections of CVD diamonds are elongated but symmetric in their profiles and are distributed regularly as they are indexed by the diamond lattice, while those of shock effect are also elongated and asymmetric, and are distributed at random as they cannot be indexed. The characteristics observed by the method may be useful to ascribe the origin to CVD or shock effect.
2D Process-based Microbialite Growth Model
NASA Astrophysics Data System (ADS)
Airo, A.; Smith, A.
2007-12-01
A 2D process-based microbialite growth model (MGM) has been developed that integrates the coupled effects of the microbialite growth and sediment distribution within a two-dimensional cross-section of a subaqueous bedrock profile. Sediment transport is realized through particle erosion and deposition that are a function of local wave energy which is computed on the basis of linear wave theory. Surface-normal microbialite growth is directly correlated to light intensity, which is computed for every point of the microbialite surface by using a Henyey- Greenstein-type relation for scattering and the Beer's Law for absorption in the water column. Shadowing effects by surrounding obstacles and/or overlying sediment are also considered. Sediment particles can be incorporated into the microbialite framework if growth occurs in the presence of sediment. The resulting meter-size microbialite constructs develop morphologies that correspond well to natural microbialites. Furthermore, changes of environmental factors such as light intensity, wave energy, and bedrock profile result in morphological variations of the microbialites that would be expected on the basis of the current understanding of microbialite growth and development.
NASA Technical Reports Server (NTRS)
Saeed, M.; Lieu, C.; Raber, G.; Mark, R. G.
2002-01-01
Development and evaluation of Intensive Care Unit (ICU) decision-support systems would be greatly facilitated by the availability of a large-scale ICU patient database. Following our previous efforts with the MIMIC (Multi-parameter Intelligent Monitoring for Intensive Care) Database, we have leveraged advances in networking and storage technologies to develop a far more massive temporal database, MIMIC II. MIMIC II is an ongoing effort: data is continuously and prospectively archived from all ICU patients in our hospital. MIMIC II now consists of over 800 ICU patient records including over 120 gigabytes of data and is growing. A customized archiving system was used to store continuously up to four waveforms and 30 different parameters from ICU patient monitors. An integrated user-friendly relational database was developed for browsing of patients' clinical information (lab results, fluid balance, medications, nurses' progress notes). Based upon its unprecedented size and scope, MIMIC II will prove to be an important resource for intelligent patient monitoring research, and will support efforts in medical data mining and knowledge-discovery.
Design and fabrication of a new electrolarynx and voice amplifier for laryngectomees.
Sundeep Krishna, M; Jayanthy, A K; Divakar, C; Mekhala, R
2005-01-01
A Laryngectomee is a person whose vocal cords i.e. voice box is surgically removed owing to cancer or due to automobile accidents, burns or trauma. The patient, therefore permanently loses the ability to speak normally. An Electrolarynx is an electronic speech aid that enables the Laryngectomee to communicate with other people as quickly as possible after the successful removal of the larynx. A neck type Electrolarynx has been designed. Earlier designs could not alter frequency and intensity simultaneously during conversation. The Electrolarynx developed can control both frequency and intensity simultaneously during conversation. The device has been tested on the patient and found to be very effective. A portable, pocket size, battery powered voice amplifier (PA system) has also been developed which uses an electret condenser microphone as the input. The voice amplifier developed is a two stage amplifier which uses a preamplifier stage and a power amplifier stage. The output of the power amplifier is connected to a speaker. The device is being used by the patient and found to be very useful.
Novel functionalized fluorescent polymeric nanoparticles for immobilization of biomolecules
NASA Astrophysics Data System (ADS)
Jain, Swati; Chattopadhyay, Sruti; Jackeray, Richa; Abid, C. K. V. Zainul; Singh, Harpal
2013-07-01
Novel, size controlled fluorescent polymeric nanoparticles (FPNP) were synthesized having acetoacetoxy functionality on the surface for immobilization of biomolecules which can be utilized as biomarkers and labels in fluoroimmunoassays. Core-shell nanoparticles of poly(styrene, St-methyl methacrylate, MMA-acetoacetoxy ethyl methacrylate, AAEM), stabilized by various concentrations of surfactant, sodium lauryl sulphate (SLS), were obtained by facile miniemulsion co-polymerization encapsulated with pyrene molecules in their hydrophobic core. Analytical, spectroscopic and imaging characterization techniques revealed the formation of stable, monodisperse, spherical nano sized particles exhibiting high luminescence properties. Particles with 1% SLS (S1) showed good dispersion stability and fluorescence intensity and were chosen as ideal candidates for further immobilization studies. Steady state fluorescence studies showed 10 times higher fluorescence intensity of S1 nanoparticles than that of pyrene solution in solvent-toluene at the same concentration. Environmental factors such as pH, ionic strength and time were found to have no effect on fluorescence intensity of FPNPs. Surface β-di-ketone groups were utilized for the covalent immobilization of enzyme conjugated antibodies without any activation or pre-treatment of nanoparticles.Novel, size controlled fluorescent polymeric nanoparticles (FPNP) were synthesized having acetoacetoxy functionality on the surface for immobilization of biomolecules which can be utilized as biomarkers and labels in fluoroimmunoassays. Core-shell nanoparticles of poly(styrene, St-methyl methacrylate, MMA-acetoacetoxy ethyl methacrylate, AAEM), stabilized by various concentrations of surfactant, sodium lauryl sulphate (SLS), were obtained by facile miniemulsion co-polymerization encapsulated with pyrene molecules in their hydrophobic core. Analytical, spectroscopic and imaging characterization techniques revealed the formation of stable, monodisperse, spherical nano sized particles exhibiting high luminescence properties. Particles with 1% SLS (S1) showed good dispersion stability and fluorescence intensity and were chosen as ideal candidates for further immobilization studies. Steady state fluorescence studies showed 10 times higher fluorescence intensity of S1 nanoparticles than that of pyrene solution in solvent-toluene at the same concentration. Environmental factors such as pH, ionic strength and time were found to have no effect on fluorescence intensity of FPNPs. Surface β-di-ketone groups were utilized for the covalent immobilization of enzyme conjugated antibodies without any activation or pre-treatment of nanoparticles. Electronic supplementary information (ESI) available: Resulting ATR-FTIR spectrum and procedure to study fluorescence of nanoparticles, effect of particle size, concentration, pH, ionic strength and time on Fl intensity of FPNP. See DOI: 10.1039/c3nr34100c
The size effect to O2- -Ce4+ charge transfer emission and band gap structure of Sr2 CeO4.
Wang, Wenjun; Pan, Yu; Zhang, Wenying; Liu, Xiaoguang; Li, Ling
2018-04-24
Sr 2 CeO 4 phosphors with different crystalline sizes were synthesized by the sol-gel method or the solid-state reaction. Their crystalline size, luminescence intensity of O 2- -Ce 4+ charge transfer and energy gaps were obtained through the characterization by X-ray diffraction, photoluminescence spectra, as well as UV-visible diffuse reflectance measurements. An inverse relationship between photoluminescence (PL) spectra and crystalline size was observed when the heating temperature was from 1000°C to 1300°C. In addition, band energy calculated for all samples showed that a reaction temperature of 1200°C for the solid-state method and 1100°C for sol-gel method gave the largest values, which corresponded with the smallest crystalline size. Correlation between PL intensity and crystalline size showed an inverse relationship. Band structure, density of states and partial density of states of the crystal were calculated to analyze the mechanism using the cambrige sequential total energy package (CASTEP) module integrated with Materials Studio software. Copyright © 2018 John Wiley & Sons, Ltd.
Surface-enhanced Raman spectroscopy on laser-engineered ruthenium dye-functionalized nanoporous gold
NASA Astrophysics Data System (ADS)
Schade, Lina; Franzka, Steffen; Biener, Monika; Biener, Jürgen; Hartmann, Nils
2016-06-01
Photothermal processing of nanoporous gold with a microfocused continuous-wave laser at λ = 532 nm provides a facile means in order engineer the pore and ligament size of nanoporous gold. In this report we take advantage of this approach in order to investigate the size-dependence of enhancement effects in surface-enhanced Raman spectroscopy (SERS). Surface structures with laterally varying pore sizes from 25 nm to ≥200 nm are characterized using scanning electron microscopy and then functionalized with N719, a commercial ruthenium complex, which is widely used in dye-sensitized solar cells. Raman spectroscopy reveals the characteristic spectral features of N719. Peak intensities strongly depend on the pore size. Highest intensities are observed on the native support, i.e. on nanoporous gold with pore sizes around 25 nm. These results demonstrate the particular perspectives of laser-fabricated nanoporous gold structures in fundamental SERS studies. In particular, it is emphasized that laser-engineered porous gold substrates represent a very well defined platform in order to study size-dependent effects with high reproducibility and precision and resolve conflicting results in previous studies.
Holsti, Liisa; Grunau, Ruth E
2007-06-01
Accurate assessment and treatment of pain and stress in preterm infants in neonatal intensive care units (NICU) is vital because pain and stress responses have been linked to long-term alterations in development in this population. To review the evidence of specific extremity movements in preterm infants as observed during stressful procedures. Five on-line databases were searched for relevant studies. For each study, levels of evidence were determined and effect size estimates were calculated. Each study was also evaluated for specific factors that presented potential threats to its validity. Eighteen studies were identified and seven comprised the review. The combined sample included 359 preterm infants. Six specific movements were associated with painful and intrusive procedures. A set of specific extremity movements, when combined with other reliable biobehavioural measures of pain and stress, can form the basis for future research and development of a clinical stress scale for preterm infants.
Crack propagation in aluminum sheets reinforced with boron-epoxy
NASA Technical Reports Server (NTRS)
Roderick, G. L.
1979-01-01
An analysis was developed to predict both the crack growth and debond growth in a reinforced system. The analysis was based on the use of complex variable Green's functions for cracked, isotropic sheets and uncracked, orthotropic sheets to calculate inplane and interlaminar stresses, stress intensities, and strain-energy-release rates. An iterative solution was developed that used the stress intensities and strain-energy-release rates to predict crack and debond growths, respectively, on a cycle-by-cycle basis. A parametric study was made of the effects of boron-epoxy composite reinforcement on crack propagation in aluminum sheets. Results show that the size of the debond area has a significant effect on the crack propagation in the aluminum. For small debond areas, the crack propagation rate is reduced significantly, but these small debonds have a strong tendency to enlarge. Debond growth is most likely to occur in reinforced systems that have a cracked metal sheet reinforced with a relatively thin composite sheet.
Stimulated Raman diagnostics in diesel droplets
NASA Astrophysics Data System (ADS)
Golombok, Michael
1991-09-01
Stimulated Raman spectroscopy (SRS) can simultaneously measure droplet sizes and the associated component concentrations in a fuel injection. As spray evaporation is crucial in determining the performance parameters of a diesel engine, such as cold start and particulate emission formation, the new application of the method for spatially and temporally resolved measurements is a useful new diagnostic, extending our understanding of spray processes. Droplet sizes can be obtained from single shot SRS spectra by measuring the separation between morphology-dependent resonances (MDR) that correspond to standing wave modes confined near the droplet circumference. Power spectrum analysis allows the measurement of more than one droplet from a spectrum using a pumped laser sheet in the fuel spray. The MDRs are responsible for the simultaneous stimulation of multiple Raman spectral lines over and above those seen in bulk liquids. The SRS method for concentration measurement is effectively self-calibrating in that the relative intensity of two adjacent lines is used to measure concentration. Any particular fuel has a unique ratio of SRS antisymmetric to symmetric C-H stretch intensity. If individual components in a fuel blend are characterized beforehand, one can monitor the evolution of the spray during injection by measuring signal intensity ratios which yield the volume fraction of the component of interest. The SRS technique is being used to examine a number of spray dynamics phenomena such as fuel atomization, droplet evolution and front-end volatility effects, which are of current interest in diesel development studies.
1986-05-01
8217..".. .4.-,: -, 4’.-. -I I" " " . " "" .. -"" " " " +,’" ŗŖ. -II O CHART -JON SECIJRITY CLASSIFICATION OF THIS PAGE (When DateEntered) REPORT ...DOCUMENTATION PAGE BEFORE COMPLETING FORM I. REPORT NUMBER 2. GOVT ACCESSION NO. 3. RECIPIENT’S CATALOG NUMBER ~AFIT/CI/NR-86-28T 4. TITLE (and Subtitle) S...TYPE OF REPORT & PERIOD COVERED Objective Analysis of Tropical Cyclone THESIS/ Intensity, Strength, and Size Using Routine Aircraft Reconnaissance
Laser scattering method applied to determine the concentration of alfa 1-antitrypsin
NASA Astrophysics Data System (ADS)
Riquelme, Bibiana D.; Foresto, Patricia; Valverde, Juana R.; Rasia, Rodolfo J.
2000-04-01
An optical method has been developed to find (alpha) 1- antitrypsin unknown concentrations in human serum samples. This method applies light scattering properties exhibited by initially formed enzyme-inhibitor complexes and uses the curves of aggregation kinetics. It is independent of molecular hydrodynamics. Theoretical approaches showed that scattering properties of transient complexes obey the Rayleigh-Debie conditions. Experiments were performed on the Trypsin/(alpha) 1-antitrypsin system. Measurements were performed in newborn, adult and pregnant sera containing (alpha) 1-antitrypsin in the Trypsin excess region. The solution was excite by a He-Ne laser beam. SO, the particles formed during the reaction are scattering centers for the interacting light. The intensity of the scattered light at 90 degrees from incident beam depends on the nature of those scattering centers. Th rate of increase in scattered intensity depends on the variation in size and shape of the scatterers, being independent of its original size. Peak values of the first derivative linearly correlate with the concentration of (alpha) 1-antitrypsin originally present in the sample. Results are displayed 5 minutes after the initiation of the experimental process. Such speed is of great importance in the immuno-biochemistry determinations.
Assessing the Urban Heat Island Effect Across Biomes in the Continental USA Using Landsat and MODIS
NASA Technical Reports Server (NTRS)
Imhoff, Marc L.; Bounoua, L.; Zhang, Ping; Wolfe, Robert
2011-01-01
Impervious surface area (ISA) from the Landsat TM and land surface temperature (LST) from MODIS averaged over three annual cycles (2003-2005) are used in a spatial analysis to assess the urban heat island (UHI) skin temperature amplitude and its relationship to development intensity, size, and ecological setting for 38 of the most populous cities in the continental United States. Development intensity zones based on %ISA are defined across urban gradients and used to stratify sampling of LST and NDVI. We find that ecological context significantly influences the amplitude of summer daytime UHI (urban - rural temperature difference) with the largest 8 C (average) for cities built in mixed forest biomes. For all cities ISA is the primary driver for increase in temperature explaining 70% of the total variance. Annually, urban areas are warmer than the non-urban fringe by 2.9 C, except in biomes with arid and semiarid climates. The average amplitude of the UHI is asymmetric with a 4.3 C difference in summer and 1.3 C in winter. In desert environments, UHI's point to a possible heat sink effect. Results show that the urban heat island amplitude increases with city size and is seasonally asymmetric for a large number of cities across most biomes. The implications are that for urban areas developed within forested ecosystems the summertime UHI can be quite high relative to the wintertime UHI suggesting that the residential energy consumption required for summer cooling is likely to increase with urban growth within those biomes.
Synthesis of suitable SiO2 nano particles as the core in core-shell nanostructured materials.
Ghahari, Mehdi; Aghababazadeh, Roya; Ebadzadeh, Touradj; Mirhabibi, Alireza; Brydson, Rik; Fabbri, Paola; Najafi, Farhod
2011-06-01
The effect of surfactant on the luminescent intensity of SiO2 @Y2O3:Eu3+ particles with a core shell structure is described. Core-shell particles are used in phosphor materials and employing spherical particles with a narrow size distribution is vital for the enhancement of luminescent properties. Three kinds of different surfactants were used to synthesis SiO2 nano particles via a sol gel process. The results demonstrated that comb polycarboxylic acid surfactant had a significant influence on the morphology and particle size distribution. Somehow, particles with 100 nm size and narrow size distribution were produced. These particles had relatively uniform packing, unlike particles produced with other surfactants or without surfactant which had irregular assembly. The photoluminescence intensity of SiO2 @Y2O3:Eu3+ particles that was synthesized by comb polycarboxylic acid surfactant was higher than those which were produced without surfactant.
NASA Astrophysics Data System (ADS)
Gray, Robert H. R.; Leslie, Thomas A.; Civale, John; Kennedy, James E.; ter Haar, Gail
2007-05-01
Real time ultrasound monitoring of tissue ablation in clinical HIFU treatments currently depends on the observation of the appearance of new hyperechoic regions within the target volume, allowing visually directed treatment. These grey-scale changes are attributed to the formation of gas or vapour bubbles. In this study, scanned track lesions have been formed in ex vivo bovine liver samples at a range of ablative intensities (free field spatial peak intensities 7 - 47 kW cm-2), and tracking speeds (1-2 mms-1). Their appearance on conventional B-mode ultrasound images has been assessed using digital imaging techniques over the first 60 seconds following HIFU exposure. The size of the lesion as seen on the ultrasound scan is compared to the macroscopic size of the lesion at dissection. It is seen that the lesion size is highly dependent on the intensity and scanning speed of the transducer. Reliable lesions can be created using scanned tracks at the lowest powers, with increased numbers of cycles, and grey-scale changes correlated strongly with the histological findings. Although not a highly sensitive indication of ablated area, ultrasound monitoring of treatment is highly specific thus confirming its clinical utility.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Beltran, C; Kamal, H
Purpose: To provide a multicriteria optimization algorithm for intensity modulated radiation therapy using pencil proton beam scanning. Methods: Intensity modulated radiation therapy using pencil proton beam scanning requires efficient optimization algorithms to overcome the uncertainties in the Bragg peaks locations. This work is focused on optimization algorithms that are based on Monte Carlo simulation of the treatment planning and use the weights and the dose volume histogram (DVH) control points to steer toward desired plans. The proton beam treatment planning process based on single objective optimization (representing a weighted sum of multiple objectives) usually leads to time-consuming iterations involving treatmentmore » planning team members. We proved a time efficient multicriteria optimization algorithm that is developed to run on NVIDIA GPU (Graphical Processing Units) cluster. The multicriteria optimization algorithm running time benefits from up-sampling of the CT voxel size of the calculations without loss of fidelity. Results: We will present preliminary results of Multicriteria optimization for intensity modulated proton therapy based on DVH control points. The results will show optimization results of a phantom case and a brain tumor case. Conclusion: The multicriteria optimization of the intensity modulated radiation therapy using pencil proton beam scanning provides a novel tool for treatment planning. Work support by a grant from Varian Inc.« less
Li, Aiyun; Song, Zhiqiang
2014-01-01
α-Keto acid of pefloxacin mesylate (PFLX) can form the complex with Terbium(III). The intramolecular energy from PFLX to Terbium(III) ion takes place when excited, and thus Terbium(III) excited state is formed and then emits the characteristic fluorescence of Terbium(III), locating at 490, 545, 580, and 620 nm. The second-order scattering (SOS) peak at 545 nm also appears for the complex with the exciting wavelength of 273 nm. When the silver nanoparticles are added to the system, the luminescence intensity at 545 nm greatly increased. So, with the adding of nanoparticles to the Terbium(III)-PFLX complex, not only is the intramolecular energy promoted but also the SOS intensity is enhanced. The experimental results show that it is the silver nanoparticles with certain size and certain concentration which can greatly enhance the fluorescence-SOS intensity, and the relative intensity at 545 nm is proportional to the amount of PFLX. Based on this phenomenon, a novel method for the determination of PFLX has been developed and applied to the determination of PFLX in capsule and serum samples. PMID:24892083
Turbulence in planetary occultations. IV - Power spectra of phase and intensity fluctuations
NASA Technical Reports Server (NTRS)
Haugstad, B. S.
1979-01-01
Power spectra of phase and intensity scintillations during occultation by turbulent planetary atmospheres are significantly affected by the inhomogeneous background upon which the turbulence is superimposed. Such coupling is particularly pronounced in the intensity, where there is also a marked difference in spectral shape between a central and grazing occultation. While the former has its structural features smoothed by coupling to the inhomogeneous background, such features are enhanced in the latter. Indeed, the latter power spectrum peaks around the characteristic frequency that is determined by the size of the free-space Fresnel zone and the ray velocity in the atmosphere; at higher frequencies strong fringes develop in the power spectrum. A confrontation between the theoretical scintillation spectra computed here and those calculated from the Mariner 5 Venus mission by Woo et al. (1974) is inconclusive, mainly because of insufficient statistical resolution. Phase and/or intensity power spectra computed from occultation data may be used to deduce characteristics of the turbulence and to distinguish turbulence from other perturbations in the refractive index. Such determinations are facilitated if observations are made at two or more frequencies (radio occultation) or in two or more colors (stellar occultation).
Baek, Sang-Soo; Choi, Dong-Ho; Jung, Jae-Woon; Lee, Hyung-Jin; Lee, Hyuk; Yoon, Kwang-Sik; Cho, Kyung Hwa
2015-12-01
Currently, continued urbanization and development result in an increase of impervious areas and surface runoff including pollutants. Also one of the greatest issues in pollutant emissions is the first flush effect (FFE), which implies a greater discharge rate of pollutant mass in the early part in the storm. Low impact development (LID) practices have been mentioned as a promising strategy to control urban stormwater runoff and pollution in the urban ecosystem. However, this requires many experimental and modeling efforts to test LID characteristics and propose an adequate guideline for optimizing LID management. In this study, we propose a novel methodology to optimize the sizes of different types of LID by conducting intensive stormwater monitoring and numerical modeling in a commercial site in Korea. The methodology proposed optimizes LID size in an attempt to moderate FFE on a receiving waterbody. Thereby, the main objective of the optimization is to minimize mass first flush (MFF), which is an indicator for quantifying FFE. The optimal sizes of 6 different LIDs ranged from 1.2 mm to 3.0 mm in terms of runoff depths, which significantly moderate the FFE. We hope that the new proposed methodology can be instructive for establishing LID strategies to mitigate FFE. Copyright © 2015 Elsevier Ltd. All rights reserved.
Data intensive computing at Sandia.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Wilson, Andrew T.
2010-09-01
Data-Intensive Computing is parallel computing where you design your algorithms and your software around efficient access and traversal of a data set; where hardware requirements are dictated by data size as much as by desired run times usually distilling compact results from massive data.
Korolev, Y N; Bobrovnitskii, I P; Geniatulina, M S; Nikulina, L A; Mikhailik, L V
2018-04-09
it has been demonstrated in various experimental studies that radiation exposure produces a negative impact on the processes of spermatogenesis associated with the disturbances of the microcirculation processes in the testes and the development of cellular and intracellular disintegration expressed as destructive changes in the cells leading to their death. The objective of the present study was to detect the ultrastructural abnormalities in the cells of Sertoli and spermatogonia under conditions of their exposure to radiation and to identify the peculiarities of their regeneration under the influence of the therapeutic and prophylactic application of low-intensity ultra-high frequency (UHF) electromagnetic radiation (EMR) and low-intensity low-frequency magnetic field (MF). The experiments were carried out on 28 non-pedigree mature male rats with the body weight 180-220 g that were divided into four groups. The first study group was comprised of the animals exposed to radiation followed by the application of low-intensity ultra-high frequency UHF electromagnetic radiation EMR. The rats in the second study group experienced effects of radiation and low-intensity low-frequency MF. The animals of the third (control) group were exposed to radiation alone, and those comprising the fourth group 1 (only radiation exposure) were considered to be intact. The studies with the use of electron microscopy showed that the therapeutic and prophylactic application of low-intensity ultra-high frequency (UHF) electromagnetic radiation and low-intensity low-frequency magnetic field caused the decrease in the number and the severity of post-radiation defects in the treated cells together with the increase of the number and size of mitochondria as well as hyperplasia of ribosomes; moreover, it promoted cellular and intracellular regeneration. UHF electromagnetic radiation had a more pronounced stimulating effect on the regeneration processes as compared with low-frequency MF. Particularly active processes of intracellular regeneration evolved in Sertoli cells; they were manifested as the increase in the number and size of mitochondria, enhanced hyperplasia of ribosomes, and formation of polysomes and new membranes of the granular endoplasmic reticulum. In spermatogonia, intracellular regeneration was less pronounced than in the Sertoli cells but was accompanied by enhanced cell regeneration and a greater number of reserve stem/progenitor cells. The results of the present study provide a rationale for the possibility of the application of a low-frequency magnetic field and especially UHF electromagnetic radiation for the further development of the promising therapeutic and preventive technologies with a view to their introduction into routine clinical practice dealing with radiation-induced pathology.
Phase Transitions of Nanoemulsions Using Ultrasound: Experimental Observations
Singh, Ram; Husseini, Ghaleb A.; Pitt, William G.
2012-01-01
The ultrasound-induced transformation of perfluorocarbon liquids to gases is of interest in the area of drug and gene delivery. In this study, three independent parameters (temperature, size, and perfluorocarbon species) were selected to investigate the effects of 476-kHz and 20-kHz ultrasound on nanoemulsion phase transition. Two levels of each factor (low and high) were considered at each frequency. The acoustic intensities at gas bubble formation and at the onset of inertial cavitation were recorded and subsequently correlated with the acoustic parameters. Experimental data showed that low frequencies are more effective in forming and collapsing a bubble. Additionally, as the size of the emulsion droplet increased, the intensity required for bubble formation decreased. As expected, perfluorohexane emulsions require greater intensity to form cavitating bubbles than perfluoropentane emulsions. PMID:22444691
Scott, Timothy C.; Wham, Robert M.
1988-01-01
A method and system for solvent extraction where droplets are shattered by a high intensity electric field. These shattered droplets form a plurality of smaller droplets which have a greater combined surface area than the original droplet. Dispersion, coalescence and phase separation are accomplished in one vessel through the use of the single pulsing high intensity electric field. Electric field conditions are chosen so that simultaneous dispersion and coalescence are taking place in the emulsion formed in the electric field. The electric field creates a large amount of interfacial surface area for solvent extraction when the droplet is disintegrated and is capable of controlling droplet size and thus droplet stability. These operations take place in the presence of a counter current flow of the continuous phase.
Biodetection using fluorescent quantum dots
NASA Astrophysics Data System (ADS)
Speckman, Donna M.; Jennings, Travis L.; LaLumondiere, Steven D.; Klimcak, Charles M.; Moss, Steven C.; Loper, Gary L.; Beck, Steven M.
2002-07-01
Multi-pathogen biosensors that take advantage of sandwich immunoassay detection schemes and utilize conventional fluorescent dye reporter molecules are difficult to make into extremely compact and autonomous packages. The development of a multi-pathogen, immunoassay-based, fiber optic detector that utilizes varying sized fluorescent semiconductor quantum dots (QDs) as the reporter labels has the potential to overcome these problems. In order to develop such a quantum dot-based biosensor, it is essential to demonstrate that QDs can be attached to antibody proteins, such that the specificity of the antibody is maintained. We have been involved in efforts to develop a reproducible method for attaching QDs to antibodies for use in biodetection applications. We have synthesized CdSe/ZnS core-shell QDs of differing size, functionalized their surfaces with several types of organic groups for water solubility, and covalently attached these functionalized QDs to rabbit anti-ovalbumin antibody protein. We also demonstrated that these labeled antibodies exhibit selective binding to ovalbumin antigen. We characterized the QDs at each step in the overall synthesis by UV-VIS absorption spectroscopy and by picosecond (psec) transient photoluminescence (TPL) spectroscopy. TPL spectroscopy measurements indicate that QD lifetime depends on the size of the QD, the intensity of the optical excitation source, and whether or not they are functionalized and conjugated to antibodies. We describe details of these experiments and discuss the impact of our results on our biosensor development program.
Characteristics of Landslide Size Distribution in Response to Different Rainfall Scenarios
NASA Astrophysics Data System (ADS)
Wu, Y.; Lan, H.; Li, L.
2017-12-01
There have long been controversies on the characteristics of landslide size distribution in response to different rainfall scenarios. For inspecting the characteristics, we have collected a large amount of data, including shallow landslide inventory with landslide areas and landslide occurrence times recorded, and a longtime daily rainfall series fully covering all the landslide occurrences. Three indexes were adopted to quantitatively describe the characteristics of landslide-related rainfall events, which are rainfall duration, rainfall intensity, and the number of rainy days. The first index, rainfall duration, is derived from the exceptional character of a landslide-related rainfall event, which can be explained in terms of the recurrence interval or return period, according to the extreme value theory. The second index, rainfall intensity, is the average rainfall in this duration. The third index is the number of rainy days in this duration. These three indexes were normalized using the standard score method to ensure that they are in the same order of magnitude. Based on these three indexes, landslide-related rainfall events were categorized by a k-means method into four scenarios: moderate rainfall, storm, long-duration rainfall, and long-duration intermittent rainfall. Then, landslides were in turn categorized into four groups according to the scenarios of rainfall events related to them. Inverse-gamma distribution was applied to characterize the area distributions of the four different landslide groups. A tail index and a rollover of the landslide size distribution can be obtained according to the parameters of the distribution. Characteristics of landslide size distribution show that the rollovers of the size distributions of landslides related to storm and long-duration rainfall are larger than those of landslides in the other two groups. It may indicate that the location of rollover may shift right with the increase of rainfall intensity and the extension of rainfall duration. In addition, higher rainfall intensities are prone to trigger larger rainfall-induced landslides since the tail index of landslide area distribution are smaller for higher rainfall intensities, which indicate higher probabilities of large landslides.
Simon, Julianna C.; Sapozhnikov, Oleg A.; Khokhlova, Vera A.; Wang, Yak-Nam; Crum, Lawrence A.; Bailey, Michael R.
2012-01-01
Atomization and fountain formation is a well-known phenomenon that occurs when a focused ultrasound wave in liquid encounters an air interface. High intensity focused ultrasound (HIFU) has been shown to fractionate tissue into submicron-size fragments in a process termed boiling histotripsy, wherein the focused ultrasound wave superheats the tissue at the focus, producing a millimetre-size boiling or vapour bubble in several milliseconds. Yet the question of how this millimetre-size boiling bubble creates submicron-size tissue fragments remains. The hypothesis of this work is that tissue can behave as a liquid such that it forms a fountain and atomization within the vapour bubble produced in boiling histotripsy. We describe an experiment, in which a 2-MHz HIFU transducer (maximum in situ intensity of 24,000 W/cm2) was aligned with an air-tissue interface meant to simulate the boiling bubble. Atomization and fountain formation were observed with high-speed photography and resulted in tissue erosion. Histological examination of the atomized tissue showed whole and fragmented cells and nuclei. Air-liquid interfaces were also filmed. Our conclusion was that HIFU can fountain and atomize tissue. Although this process does not entirely mimic what was observed in liquids, it does explain many aspects of tissue fractionation in boiling histotripsy. PMID:23159812
Pearce, R.D.; O'Shea, T.J.; Shankar, V.; Rupprecht, C.E.
2007-01-01
Recently, bat ectoparasites have been demonstrated to harbor pathogens of potential importance to humans. We evaluated antirabies antibody seroprevalence and the presence of ectoparasites in big brown bats (Eptesicus fuscus) sampled in 2002 and 2003 in Colorado to investigate if an association existed between ectoparasite intensity and exposure to rabies virus (RV). We used logistic regression and Akaike's Information Criteria adjusted for sample size (AICc) in a post-hoc analysis to investigate the relative importance of three ectoparasite species, as well as bat colony size, year sampled, age class, colony size, and year interaction on the presence of rabies virus neutralizing antibodies (VNA) in serum of wild E. fuscus. We obtained serum samples and ectoparasite counts from big brown bats simultaneously in 2002 and 2003. Although the presence of ectoparasites (Steatonyssus occidentalis and Spinturnix bakeri) were important in elucidating VNA seroprevalence, their intensities were higher in seronegative bats than in seropositive bats, and the presence of a third ectoparasite (Cimex pilosellus) was inconsequential. Colony size and year sampled were the most important variables in these AICc models. These findings suggest that these ectoparasites do not enhance exposure of big brown bats to RV. ?? 2007 Mary Ann Liebert, Inc.
Chan, W I; Liao, P H; Lo, K V
2010-11-01
Using the microwave-enhanced advanced oxidation process (MW/H2O2-AOP), the pH and irradiation intensity on waste activated sludge samples were investigated to provide insight to the athermal effects on nutrients release, solids destruction, particle size distribution and dewaterability, and to demonstrate their interrelationships. Carbonaceous matters and nutrients released into solution depended on the irradiation intensity and time. Higher irradiation levels tended to be more effective in the solubilization of nutrients and had more pronounced effects in the dewaterability of sludge. In terms of particle size distribution, detectable particles increased in size for treatments in acidic conditions, while the dewaterability of treated sludge was improved. In treatments under neutral and alkaline conditions, the particle size range increased, with more small particles formed, thereby significantly deteriorating the dewaterability of sludge treated in alkaline conditions. The best results for the solubilization of nutrients were in alkaline conditions with high irradiation power, but dewaterability of the sludge was compromised. Sludge treatment with the MW/H2O2-AOP in acidic conditions with high irradiation power yielded the best dewaterable sludge and significant nutrient solubilization; therefore, it is the recommended treatment condition for activated sludge.
Blood cell counting and classification by nonflowing laser light scattering method
NASA Astrophysics Data System (ADS)
Yang, Ye; Zhang, Zhenxi; Yang, Xinhui; Jiang, Dazong; Yeo, Joon Hock
1999-11-01
A new non-flowing laser light scattering method for counting and classifying blood cells is presented. A linear charge- coupled device with 1024 elements is used to detect the scattered light intensity distribution of the blood cells. A pinhole plate is combined with the CCD to compete the focusing of the measurement system. An isotropic sphere is used to simulate the blood cell. Mie theory is used to describe the scattering of blood cells. In order to inverse the size distribution of blood cells from their scattered light intensity distribution, Powell method combined with precision punishment method is used as a dependent model method for measurement red blood cells and blood plates. Non-negative constraint least square method combined with Powell method and precision punishment method is used as an independent model for measuring white blood cells. The size distributions of white blood cells and red blood cells, and the mean diameter of red blood cells are measured by this method. White blood cells can be divided into three classes: lymphocytes, middle-sized cells and neutrocytes according to their sizes. And the number of blood cells in unit volume can also be measured by the linear dependence of blood cells concentration on scattered light intensity.
Novy, Diane M; Engle, Mitchell P; Lai, Emily A; Cook, Christina; Martin, Emily C; Trahan, Lisa; Yu, Jun; Koyyalagunta, Dhanalakshmi
2016-07-01
The effectiveness of splanchnic nerve neurolysis (SNN) for cancer-related abdominal pain has been investigated using numeric pain intensity rating as an outcome variable. The outcome variable in this study used the grid method for obtaining a targeted pain drawing score on 60 patients with pain from pancreatic or gastro-intestinal primary cancers or metastatic disease to the abdominal region. Results demonstrate excellent inter-rater agreement (intra-class correlation [ICC] coefficient at pre-SNN = 0.97 and ICC at within one month post-SNN = 0.98) for the grid method of scoring the pain drawing and demonstrate psychometric generalizability among patients with cancer-related pain. Using the Wilcoxon signed rank test and associated effect sizes, results show significant improvement in dispersion of pain following SNN. Effect sizes for the difference in pre-SNN to 2 post-SNN time points were higher for the pain drawing than for pain intensity rating. Specifically, the effect size difference from pre- to within one month post-SNN was r = 0.42 for pain drawing versus r = 0.23 for pain intensity rating. Based on a smaller subset of patients who were seen within 1 - 6 months following SNN, the effect size difference from pre-SNN was r = 0.46 for pain drawing versus r = 0.00 for pain intensity rating. Collectively, these data support the use of the pain drawing as a reliable outcome measure among patients with cancer pain for procedures such as SNN that target specific location and dispersion of pain.
NASA Astrophysics Data System (ADS)
Shin, Jung-Wook; Park, Jinku; Choi, Jang-Geun; Jo, Young-Heon; Kang, Jae Joong; Joo, HuiTae; Lee, Sang Heon
2017-12-01
The aim of this study was to examine the size structure of phytoplankton under varying coastal upwelling intensities and to determine the resulting primary productivity in the southwestern East Sea. Samples of phytoplankton assemblages were collected on five occasions from the Hupo Bank, off the east coast of Korea, during 2012-2013. Because two major surface currents have a large effect on water mass transport in this region, we first performed a Backward Particle Tracking Experiment (BPTE) to determine the coastal sea from which the collected samples originated according to advection time of BPTE particles, following which we used upwelling age (UA) to determine the intensity of coastal upwelling in the region of origin for each sample. Only samples that were affected by coastal upwelling in the region of origin were included in subsequent analyses. We found that as UA increased, there was a decreasing trend in the concentration of picophytoplankton, and increasing trends in the concentration of nanophytoplankton and microphytoplankton. We also examined the relationship between the size structure of phytoplankton and primary productivity in the Ulleung Basin (UB), which has experienced significant variation over the past decade. We found that primary productivity in UB was closely related to the strength of the southerly wind, which is the most important mechanism for coastal upwelling in the southwestern East Sea. Thus, the size structure of phytoplankton is determined by the intensity of coastal upwelling, which is regulated by the southerly wind, and makes an important contribution to primary productivity.
Kic size effect study on two high-strength steels using notched bend specimens
NASA Technical Reports Server (NTRS)
Stonesifer, F. R.
1974-01-01
Five methods are used to calculate plane strain fracture toughness (K sub Q) values for bend-specimens of various sizes from two high-strength steels. None of the methods appeared to satisfactorily predict valid stress intensity factor (K sub IC) values from specimens of sizes well below that required by E399 standard tests.
Robinson, B F; Mervis, C B
1998-03-01
The early lexical and grammatical development of 1 male child is examined with growth curves and dynamic-systems modeling procedures. Lexical-development described a pattern of logistic growth (R2 = .98). Lexical and plural development shared the following characteristics: Plural growth began only after a threshold was reached in vocabulary size; lexical growth slowed as plural growth increased. As plural use reached full mastery, lexical growth began again to increase. It was hypothesized that a precursor model (P. van Geert, 1991) would fit these data. Subsequent testing indicated that the precursor model, modified to incorporate brief yet intensive plural growth, provided a suitable fit. The value of the modified precursor model for the explication of processes implicated in language development is discussed.
The role of emotions in the maintenance of cooperative behaviors
NASA Astrophysics Data System (ADS)
Zhang, Chunyan; Zhang, Jianlei; Weissing, Franz J.
2014-04-01
Our attention is focused on how individual emotions influence collective behaviors, which captures an aspect of reality missing from past studies: free riders may suffer some stress, which could adapt jointly with the individual stress intensity and size of the gaming group. With an evolutionary game theoretical approach, we gain the fixation probability for one mutant cooperator to invade and dominate the whole defecting population. When the stress intensity exceeds a threshold, natural selection favors cooperators replacing defectors in a finite population. We further infer that lower stress intensity is sufficient for one mutant cooperator to become fixed with an advantageous probability in a larger population. Moreover, when the gaming group is smaller than the population size, the more the return from the public goods, the lower the threshold of stress intensity required to facilitate the full dominance of cooperators. We hope our studies may show that individual sentiments or psychological activities will open up novel explanations for the puzzle of collective actions.
Income Disparities and the Global Distribution of Intensively Farmed Chicken and Pigs
Gilbert, Marius; Conchedda, Giulia; Van Boeckel, Thomas P.; Cinardi, Giuseppina; Linard, Catherine; Nicolas, Gaëlle; Thanapongtharm, Weerapong; D'Aietti, Laura; Wint, William; Newman, Scott H.; Robinson, Timothy P.
2015-01-01
The rapid transformation of the livestock sector in recent decades brought concerns on its impact on greenhouse gas emissions, disruptions to nitrogen and phosphorous cycles and on land use change, particularly deforestation for production of feed crops. Animal and human health are increasingly interlinked through emerging infectious diseases, zoonoses, and antimicrobial resistance. In many developing countries, the rapidity of change has also had social impacts with increased risk of marginalisation of smallholder farmers. However, both the impacts and benefits of livestock farming often differ between extensive (backyard farming mostly for home-consumption) and intensive, commercial production systems (larger herd or flock size, higher investments in inputs, a tendency towards market-orientation). A density of 10,000 chickens per km2 has different environmental, epidemiological and societal implications if these birds are raised by 1,000 individual households or in a single industrial unit. Here, we introduce a novel relationship that links the national proportion of extensively raised animals to the gross domestic product (GDP) per capita (in purchasing power parity). This relationship is modelled and used together with the global distribution of rural population to disaggregate existing 10 km resolution global maps of chicken and pig distributions into extensive and intensive systems. Our results highlight countries and regions where extensive and intensive chicken and pig production systems are most important. We discuss the sources of uncertainties, the modelling assumptions and ways in which this approach could be developed to forecast future trajectories of intensification. PMID:26230336
Income Disparities and the Global Distribution of Intensively Farmed Chicken and Pigs.
Gilbert, Marius; Conchedda, Giulia; Van Boeckel, Thomas P; Cinardi, Giuseppina; Linard, Catherine; Nicolas, Gaëlle; Thanapongtharm, Weerapong; D'Aietti, Laura; Wint, William; Newman, Scott H; Robinson, Timothy P
2015-01-01
The rapid transformation of the livestock sector in recent decades brought concerns on its impact on greenhouse gas emissions, disruptions to nitrogen and phosphorous cycles and on land use change, particularly deforestation for production of feed crops. Animal and human health are increasingly interlinked through emerging infectious diseases, zoonoses, and antimicrobial resistance. In many developing countries, the rapidity of change has also had social impacts with increased risk of marginalisation of smallholder farmers. However, both the impacts and benefits of livestock farming often differ between extensive (backyard farming mostly for home-consumption) and intensive, commercial production systems (larger herd or flock size, higher investments in inputs, a tendency towards market-orientation). A density of 10,000 chickens per km2 has different environmental, epidemiological and societal implications if these birds are raised by 1,000 individual households or in a single industrial unit. Here, we introduce a novel relationship that links the national proportion of extensively raised animals to the gross domestic product (GDP) per capita (in purchasing power parity). This relationship is modelled and used together with the global distribution of rural population to disaggregate existing 10 km resolution global maps of chicken and pig distributions into extensive and intensive systems. Our results highlight countries and regions where extensive and intensive chicken and pig production systems are most important. We discuss the sources of uncertainties, the modelling assumptions and ways in which this approach could be developed to forecast future trajectories of intensification.
Final Scientific Report: DE-SC0002194
DOE Office of Scientific and Technical Information (OSTI.GOV)
Seidler, Gerald
We provide the final scientific report for DE-SC0002194. During the term of this grant, 28 publications spanning a variety of topics were addressed under the rubric of advanced x-ray methods and their application to extreme conditions of time-resolution or x-ray intensities. Notable accomplishments include a new observation of XANES features associated with f-shell reconfiguration in lanthanides, size-dependent x-ray heating effects under XFEL illumination conditions, theoretical development of improved treatments of inelastic x-ray scattering for 'warm dense matter' conditions, and several new instrument develop efforts for atomic, molecular, and condensed phase studies in the lab and at major facility lightsources.
Fourier optics analysis of grating sensors with tilt errors.
Ferhanoglu, Onur; Toy, M Fatih; Urey, Hakan
2011-06-15
Dynamic diffraction gratings can be microfabricated with precision and offer extremely sensitive displacement measurements and light intensity modulation. The effect of pure translation of the moving part of the grating on diffracted order intensities is well known. This study focuses on the parameters that limit the intensity and the contrast of the interference. The effects of grating duty cycle, mirror reflectivities, sensor tilt and detector size are investigated using Fourier optics theory and Gaussian beam optics. Analytical findings reveal that fringe visibility becomes <0.3 when the optical path variation exceeds half the wavelength within the grating interferometer. The fringe visibility can be compensated by monitoring the interfering portion of the diffracted order light only through detector size reduction in the expense of optical power. Experiments were conducted with a grating interferometer that resulted in an eightfold increase in fringe visibility with reduced detector size, which is in agreement with theory. Findings show that diffraction grating readout principle is not limited to translating sensors but also can be used for sensors with tilt or other deflection modes.
Mechanisms of resonant low frequency Raman scattering from metallic nanoparticle Lamb modes
NASA Astrophysics Data System (ADS)
Girard, A.; Lermé, J.; Gehan, H.; Margueritat, J.; Mermet, A.
2017-05-01
The low frequency Raman scattering from gold nanoparticle bimodal assemblies with controlled size distributions has been studied. Special care has been paid to determining the size dependence of the Raman intensity corresponding to the quadrupolar Lamb mode. Existing models based on a microscopic description of the scattering mechanism in small particles (bond polarizability, dipole induced dipole models) predict, for any Raman-active Lamb modes, an inelastic intensity scaling as the volume of the nanoparticle. Surprisingly experimental intensity ratios are found to be anomalously much greater than theoretical ones, calling into question this scaling law. To explain these discrepancies, a simple mechanism of Raman scattering, based on the density fluctuations in the nanoparticles induced by the Lamb modes, is introduced. This modeling, in which the nanoparticle is described as an elastic isotropic continuous medium—as in Lamb theory, successfully explains the major features exhibited by low frequency Raman modes. Moreover this model provides a unified picture for any material, suitable for handling both small and large size ranges, as well as non-resonant and resonant excitation conditions in the case of metallic species.
Holdsworth, Clare; Haines, Kimberley J; Francis, Jill J; Marshall, Andrea; O'Connor, Denise; Skinner, Elizabeth H
2015-12-01
Early mobilization in intensive care unit (ICU) is safe, feasible, and beneficial. However, mobilization frequently does not occur in practice. The study objective was to elicit attitudinal, normative, and control beliefs (barriers and enablers) toward the mobilization of ventilated patients, to inform development of targeted implementation interventions. A 9-item elicitation questionnaire was administered electronically to a convenience sample of multidisciplinary staff in a tertiary ICU. A snowball recruitment approach was used to target a sample size of 20 to 25. Two investigators performed word count and thematic analyses independently. Themes were cross-checked by a third investigator. Twenty-two questionnaires were completed. Respondents wrote the most text about disadvantages. Positive attitudinal beliefs included better respiratory function, reduced functional decline, and reduced muscle wasting/weakness. The main negative attitudinal beliefs were that mobilization is perceived as time consuming and poses a risk of line dislodgement/disconnection. Positive control beliefs (enablers) included increased staff availability, positive staff attitudes, engagement, and teamwork. Negative control beliefs (barriers) included unstable patient physiology and negative workplace culture. Intensive care unit staff expressed positive and negative attitudinal, normative, and control beliefs across the spectrum, and disadvantages were most frequently reported. Identified beliefs can be used to inform development of future interventions. Copyright © 2015 Elsevier Inc. All rights reserved.
Reconstruction of structural damage based on reflection intensity spectra of fiber Bragg gratings
NASA Astrophysics Data System (ADS)
Huang, Guojun; Wei, Changben; Chen, Shiyuan; Yang, Guowei
2014-12-01
We present an approach for structural damage reconstruction based on the reflection intensity spectra of fiber Bragg gratings (FBGs). Our approach incorporates the finite element method, transfer matrix (T-matrix), and genetic algorithm to solve the inverse photo-elastic problem of damage reconstruction, i.e. to identify the location, size, and shape of a defect. By introducing a parameterized characterization of the damage information, the inverse photo-elastic problem is reduced to an optimization problem, and a relevant computational scheme was developed. The scheme iteratively searches for the solution to the corresponding direct photo-elastic problem until the simulated and measured (or target) reflection intensity spectra of the FBGs near the defect coincide within a prescribed error. Proof-of-concept validations of our approach were performed numerically and experimentally using both holed and cracked plate samples as typical cases of plane-stress problems. The damage identifiability was simulated by changing the deployment of the FBG sensors, including the total number of sensors and their distance to the defect. Both the numerical and experimental results demonstrate that our approach is effective and promising. It provides us with a photo-elastic method for developing a remote, automatic damage-imaging technique that substantially improves damage identification for structural health monitoring.
Hill, Ethan C; Housh, Terry J; Keller, Joshua L; Smith, Cory M; Schmidt, Richard J; Johnson, Glen O
2018-06-22
Low-intensity venous blood flow restriction (vBFR) resistance training has been shown to promote increases in muscle strength and size. Eccentric-only muscle actions are typically a more potent stimulus to increase muscle strength and size than concentric-only muscle actions performed at the same relative intensities. Therefore, the purpose of this investigation was to examine the time-course of changes in muscle strength, hypertrophy, and neuromuscular adaptations following 4 weeks of unilateral forearm flexion low-intensity eccentric vBFR (Ecc-vBFR) vs. low-intensity concentric vBFR (Con-vBFR) resistance training performed at the same relative intensity. Thirty-six women were randomly assigned to either Ecc-vBFR (n = 12), Con-vBFR (n = 12) or control (no intervention, n = 12) group. Ecc-vBFR trained at 30% of eccentric peak torque and Con-vBFR trained at 30% of concentric peak torque. All training and testing procedures were performed at an isokinetic velocity of 120° s - ¹. Muscle strength increased similarly from 0 to 2 and 4 weeks of training as a result of Ecc-vBFR (13.9 and 35.0%) and Con-vBFR (13.4 and 31.2%), but there were no changes in muscle strength for the control group. Muscle thickness increased similarly from 0 to 2 and 4 weeks of training as a result of Ecc-vBFR (11.4 and 12.8%) and Con-vBFR (9.1 and 9.9%), but there were no changes for the control group. In addition, there were no changes in any of the neuromuscular responses. The Ecc-vBFR and Con-vBFR low-intensity training induced comparable increases in muscle strength and size. The increases in muscle strength, however, were not associated with neuromuscular adaptations.
NASA Astrophysics Data System (ADS)
Hurlock, Ashley J.
Despite increased female participation in the workforce and females earning more undergraduate degrees than men over the past decade, women are still awarded fewer undergraduate degrees than men and hold less than 25% of jobs in the areas of science, technology, engineering and math, or STEM (Beede, et al., 2011). Research shows that females may be leaking from the STEM pipeline because they are not choosing to attend institutions that fulfill their interdisciplinary and non-academic interests or have learning environments that are supportive of their needs. The purpose of this quantitative, cross-sectional survey study, conducted at one non-research intensive university, was to identify institutional factors most pertinent to the decision to attend a non-research intensive university by a "STEM qualified" female undergraduate student. 23 of 45 factors were reported as positively influencing their decision regardless of major. The top six factors for both groups were: average class size, campus environment, a visit to campus, university population size, and major/department offered. The seven factors ranked statistically significantly different between STEM and non-STEM majors were undergraduate research opportunities, faculty reputation, graduate/professional school admission, academic support/tutoring, graduate program available, intramural sports, and off-campus housing. Only two of 17 factors negatively influenced STEM majors who were accepted to a research intensive university: the research intensive university's size and average class sizes were undesirable compared to their current institution. STEM qualified females weighed the importance of non-academic factors as high, or higher, than critical academic factors. STEM qualified females are also choosing to attend the non-research intensive university for a variety of reasons and not simply because another institution did not offer certain academic factors. Future studies should expanded to include other non-research intensive universities, research intensive universities, and high schools in order to further understand the impact that certain factors have on female choice of institution. The authors strongly feel that if institutions which provide a more supportive environment for female undergraduates create successful recruitment initiatives, their female students may be more likely to persist as STEM majors. This could potentially patch one of the substantial leaks in the STEM pipeline for women.
Building child trauma theory from longitudinal studies: a meta-analysis.
Alisic, Eva; Jongmans, Marian J; van Wesel, Floryt; Kleber, Rolf J
2011-07-01
Many children are exposed to traumatic events, with potentially serious psychological and developmental consequences. Therefore, understanding development of long-term posttraumatic stress in children is essential. We aimed to contribute to child trauma theory by focusing on theory use and theory validation in longitudinal studies. Forty studies measuring short-term predictors and long-term posttraumatic stress symptoms were identified and coded for theoretical grounding, sample characteristics, and correlational effect sizes. Explicit theoretical frameworks were present in a minority of the studies. Important predictors of long-term posttraumatic stress were symptoms of acute and short-term posttraumatic stress, depression, anxiety, and parental posttraumatic stress. Female gender, injury severity, duration of hospitalization, and elevated heart rate shortly after hospitalization yielded small effect sizes. Age, minority status, and socioeconomic status were not significantly related to long-term posttraumatic stress reactions. Since many other variables were not studied frequently enough to compute effect sizes, existing theoretical frameworks could only be partially confirmed or falsified. Child trauma theory-building can be facilitated by development of encouraging journal policies, the use of comparable methods, and more intense collaboration. Copyright © 2011 Elsevier Ltd. All rights reserved.
Modeling the Dependency Structure of Integrated Intensity Processes
Ma, Yong-Ki
2015-01-01
This paper studies an important issue of dependence structure. To model this structure, the intensities within the Cox processes are driven by dependent shot noise processes, where jumps occur simultaneously and their sizes are correlated. The joint survival probability of the integrated intensities is explicitly obtained from the copula with exponential marginal distributions. Subsequently, this result can provide a very useful guide for credit risk management. PMID:26270638
On the relative intensity of Poisson’s spot
NASA Astrophysics Data System (ADS)
Reisinger, T.; Leufke, P. M.; Gleiter, H.; Hahn, H.
2017-03-01
The Fresnel diffraction phenomenon referred to as Poisson’s spot or spot of Arago has, beside its historical significance, become relevant in a number of fields. Among them are for example fundamental tests of the super-position principle in the transition from quantum to classical physics and the search for extra-solar planets using star shades. Poisson’s spot refers to the positive on-axis wave interference in the shadow of any spherical or circular obstacle. While the spot’s intensity is equal to the undisturbed field in the plane wave picture, its intensity in general depends on a number of factors, namely the size and wavelength of the source, the size and surface corrugation of the diffraction obstacle, and the distances between source, obstacle and detector. The intensity can be calculated by solving the Fresnel-Kirchhoff diffraction integral numerically, which however tends to be computationally expensive. We have therefore devised an analytical model for the on-axis intensity of Poisson’s spot relative to the intensity of the undisturbed wave field and successfully validated it both using a simple light diffraction setup and numerical methods. The model will be useful for optimizing future Poisson-spot matter-wave diffraction experiments and determining under what experimental conditions the spot can be observed.
NASA Astrophysics Data System (ADS)
Le Hardy, David; Badri, Mohd Afeef; Rousseau, Benoit; Chupin, Sylvain; Rochais, Denis; Favennec, Yann
2017-06-01
In order to explain the macroscopic radiative behaviour of an open-cell ceramic foam, knowledge of its solid phase distribution in space and the radiative contributions by this solid phase is required. The solid phase in an open-cell ceramic foam is arranged as a porous skeleton, which is itself composed of an interconnected network of ligament. Typically, ligaments being based on the assembly of grains more or less compacted, exhibit an anisotropic geometry with a concave cross section having a lateral size of one hundred microns. Therefore, ligaments are likely to emit, absorb and scatter thermal radiation. This framework explains why experimental investigations at this scale must be developed to extract accurate homogenized radiative properties regardless the shape and size of ligaments. To support this development, a 3D numerical investigation of the radiative intensity propagation through a real world ligament, beforehand scanned by X-Ray micro-tomography, is presented in this paper. The Radiative Transfer Equation (RTE), applied to the resulting meshed volume, is solved by combining Discrete Ordinate Method (DOM) and Streamline upwind Petrov-Garlekin (SUPG) numerical scheme. A particular attention is paid to propose an improved discretization procedure (spatial and angular) based on ordinate parallelization with the aim to reach fast convergence. Towards the end of this article, we present the effects played by the local radiative properties of three ceramic materials (silicon carbide, alumina and zirconia), which are often used for designing open-cell refractory ceramic foams.
Weinberger, Dov; Bor-Shavit, Elite; Barliya, Tilda; Dahbash, Mor; Kinrot, Opher; Gaton, Dan D; Nisgav, Yael; Livnat, Tami
2017-11-01
This study aims to evaluate and standardize the reliability of a mobile laser indirect ophthalmoscope in the induction of choroidal neovascularization (CNV) in a mouse model. A diode laser indirect ophthalmoscope was used to induce CNV in pigmented male C57BL/6J mice. Standardization of spot size and laser intensity was determined using different aspheric lenses with increasing laser intensities applied around the optic disc. Development of CNV was evaluated 1, 5, and 14 days post laser application using fluorescein angiography (FA), histology, and choroidal flat mounts stained for the endothelial marker CD31 and FITC-dextran. Correlation between the number of laser hits to the number and size of developed CNV lesions was determined using flat mount choroid staining. The ability of intravitreally injected anti-human and anti-mouse VEGF antibodies to inhibit CNV induced by the mobile laser was evaluated. Laser parameters were standardized on 350 mW for 100 msec, using the 90 diopter lens to accomplish the highest incidence of Bruch's membrane rupture. CNV lesions' formation was validated on days 5 and 14 post laser injury, though FA showed leakage on as early as day 1. The number of laser hits was significantly correlated with the CNV area. CNV growth was successfully inhibited by both anti-human and mouse VEGF antibodies. The mobile laser indirect ophthalmoscope can serve as a feasible and a reliable alternative method for the CNV induction in a mouse model.
Running economy : the forgotten factor in elite performance.
Foster, Carl; Lucia, Alejandro
2007-01-01
Running performance depends on maximal oxygen uptake (VO(2max)), the ability to sustain a high percentage of VO(2max) for an extended period of time and running economy. Running economy has been studied relatively less than the other factors. Running economy, measured as steady state oxygen uptake (VO(2)) at intensities below the ventilatory threshold is the standard method. Extrapolation to a common running speed (268 m/min) or as the VO(2) required to run a kilometer is the standard method of assessment. Individuals of East African origin may be systematically more economical, although a smaller body size and a thinner lower leg may be the primary factors. Strategies for improving running economy remain to be developed, although it appears that high intensity running may be a common element acting to improve economy.
Compact illumination optic with three freeform surfaces for improved beam control.
Sorgato, Simone; Mohedano, Rubén; Chaves, Julio; Hernández, Maikel; Blen, José; Grabovičkić, Dejan; Benítez, Pablo; Miñano, Juan Carlos; Thienpont, Hugo; Duerr, Fabian
2017-11-27
Multi-chip and large size LEDs dominate the lighting market in developed countries these days. Nevertheless, a general optical design method to create prescribed intensity patterns for this type of extended sources does not exist. We present a design strategy in which the source and the target pattern are described by means of "edge wavefronts" of the system. The goal is then finding an optic coupling these wavefronts, which in the current work is a monolithic part comprising up to three freeform surfaces calculated with the simultaneous multiple surface (SMS) method. The resulting optic fully controls, for the first time, three freeform wavefronts, one more than previous SMS designs. Simulations with extended LEDs demonstrate improved intensity tailoring capabilities, confirming the effectiveness of our method and suggesting that enhanced performance features can be achieved by controlling additional wavefronts.
Laser-driven powerful kHz hard x-ray source
NASA Astrophysics Data System (ADS)
Li, Minghua; Huang, Kai; Chen, Liming; Yan, Wenchao; Tao, Mengze; Zhao, Jiarui; Ma, Yong; Li, Yifei; Zhang, Jie
2017-08-01
A powerful hard x-ray source based on laser plasma interaction is developed. By introducing the kHz, 800 nm pulses onto a rotating molybdenum (Mo) disk target, intense Mo Kα x-rays are emitted with suppressed bremsstrahlung background. Results obtained with different laser intensities suggest that the dominant absorption mechanism responsible for the high conversion efficiency is vacuum heating (VH). The high degree of spatial coherence is verified. With the high average flux and a source size comparable to the laser focus spot, absorption contrast imaging and phase contrast imaging are carried out to test the imaging capability of the source. Not only useful for imaging application, this compact x-ray source is also holding great potential for ultrafast x-ray diffraction (XRD) due to the intrinsic merits such as femtosecond pulse duration and natural synchronization with the driving laser pulses.
Nonrotating Convective Self-Aggregation in a Limited Area AGCM
NASA Astrophysics Data System (ADS)
Arnold, Nathan P.; Putman, William M.
2018-04-01
We present nonrotating simulations with the Goddard Earth Observing System (GEOS) atmospheric general circulation model (AGCM) in a square limited area domain over uniform sea surface temperature. As in previous studies, convection spontaneously aggregates into humid clusters, driven by a combination of radiative and moisture-convective feedbacks. The aggregation is qualitatively independent of resolution, with horizontal grid spacing from 3 to 110 km, with both explicit and parameterized deep convection. A budget for the spatial variance of column moist static energy suggests that longwave radiative and surface flux feedbacks help establish aggregation, while the shortwave feedback contributes to its maintenance. Mechanism-denial experiments confirm that aggregation does not occur without interactive longwave radiation. Ice cloud radiative effects help support the humid convecting regions but are not essential for aggregation, while liquid clouds have a negligible effect. Removing the dependence of parameterized convection on tropospheric humidity reduces the intensity of aggregation but does not prevent the formation of dry regions. In domain sizes less than (5,000 km)2, the aggregation forms a single cluster, while larger domains develop multiple clusters. Larger domains initialized with a single large cluster are unable to maintain them, suggesting an upper size limit. Surface wind speed increases with domain size, implying that maintenance of the boundary layer winds may limit cluster size. As cluster size increases, large boundary layer temperature anomalies develop to maintain the surface pressure gradient, leading to an increase in the depth of parameterized convective heating and an increase in gross moist stability.
NASA Astrophysics Data System (ADS)
Miecznik, Grzegorz; Illing, Rainer; Petroy, Shelley; Sokolik, Irina N.
2005-07-01
Linearly polarized radiation is sensitive to the microphysical properties of aerosols, namely, to the particle- size distribution and refractive index. The discriminating power of polarized radiation increases strongly with the increasing range of scattering angles and the addition of multiple wavelengths. The polarization and directionality of the Earth's reflectances (POLDER) missions demonstrate that some aerosol properties can be successfully derived from spaceborne polarimetric, multiangular measurements at two visible wavelengths. We extend the concept to analyze the retrieval capabilities of a spaceborne instrument with six polarimetric channels at 412, 445, 555, 865, 1250, and 2250 nm, measuring approximately 100 scattering angles covering a range between 50 and 150 deg. Our focus is development of an analysis methodology that can help quantify the benefits of such multiangular and multispectral polarimetric measurements. To that goal we employ a sensitivity metric approach in a framework of the principal-component analysis. The radiances and noise used to construct the sensitivity metric are calculated with the realistic solar flux for representative orbital viewing geometries, accounting for surface reflection from the ground, and statistical and calibration errors of a notional instrument. Spherical aerosol particles covering a range of representative microphysical properties (effective radius, effective variance, real and imaginary parts of the refractive index, single-scattering albedo) are considered in the calculations. We find that there is a limiting threshold for the effective size (approximately 0.7 μm), below which the weak scattering intensity results in a decreased signal-to-noise ratio and minimal polarization sensitivity, precluding reliable aerosol retrievals. For such small particles, close to the Rayleigh scattering limit, the total intensity provides a much stronger aerosol signature than the linear polarization, inspiring retrieval when the combined signals of intensities and the polarization fraction are used. We also find a strong correlation between aerosol parameters, in particular between the effective size and the variance, which forces one to simultaneously retrieve at least these two parameters.
NASA Astrophysics Data System (ADS)
Michibayashi, K.; Kakihata, Y.; Dick, H. J.
2017-12-01
Southwest Indian Ridge (SWIR) is located to the southwest of Rodriguez Triple Junction, where three Indian ocean ridges meet (Zhou & Dick, 2013, Nature). SWIR is one of the slowest spreading ocean ridges in the world. In this study, we studied microstructural development of 21 peridotite samples obtained from Prince Edward transform fault of SWIR by PROTEA5 cruise in 1983. The peridotites consist dominantly of olivine, orthopyroxene and clinopyroxene with minor amounts of amphibole and plagioclase as well as secondary minerals such as serpentine and magnetite. The peridotites were classified into four groups based on their microstructures: 3 ultramylonites mostly consisting of extremely fine crystals (3-5µm), 13 heterogeneous tectonites consisting of coarse-grained crystals and fine-grained matrix, 1 cataclasite and 4 intensely serpentinized peridotites. Olivine Mg# is 0.90-0.91 and spinel Cr# is 0.1-0.35. Amphibole crystals have chemical compositions of tremolite and magnesio-hornblende and they were intensely deformed within the ultramylonites and the heterogeneous tectonites, indicating that they have occurred before or during intense shearing in mantle. Moreover, extremely fine grain sizes of olivine and microboudin textures in both pyroxene and spinel crystals suggest that these peridotites have been sheared under high stress conditions. Furthermore, olivine crystal-fabrics within the amphibole bearing peridotites have B and E types that could be developed under hydrous conditions, whereas olivine fabrics within the other peridotites have A and D types that could be developed under anhydrous conditions (Karato et al., 2008, Annu. Rev. Earth Planet. Sci.). Consequently, the petrophysical characteristics of peridotites in this study indicate that the uppermost mantle below the Prince Edward transform fault has been locally but intensely hydrated during shearing due to transform movement.
Imaging of mesoscopic-scale organisms using selective-plane optoacoustic tomography.
Razansky, Daniel; Vinegoni, Claudio; Ntziachristos, Vasilis
2009-05-07
Mesoscopic-scale living organisms (i.e. 1 mm to 1 cm sized) remain largely inaccessible by current optical imaging methods due to intensive light scattering in tissues. Therefore, imaging of many important model organisms, such as insects, fishes, worms and similarly sized biological specimens, is currently limited to embryonic or other transparent stages of development. This makes it difficult to relate embryonic cellular and molecular mechanisms to consequences in organ function and animal behavior in more advanced stages and adults. Herein, we have developed a selective-plane illumination optoacoustic tomography technique for in vivo imaging of optically diffusive organisms and tissues. The method is capable of whole-body imaging at depths from the sub-millimeter up to centimeter range with a scalable spatial resolution in the order of magnitude of a few tenths of microns. In contrast to pure optical methods, the spatial resolution here is not determined nor limited by light diffusion; therefore, such performance cannot be achieved by any other optical imaging technology developed so far. The utility of the method is demonstrated on several whole-body models and small-animal extremities.
Quantification of intensive hybrid coastal reclamation for revealing its impacts on macrozoobenthos
NASA Astrophysics Data System (ADS)
Yan, Jiaguo; Cui, Baoshan; Zheng, Jingjing; Xie, Tian; Wang, Qing; Li, Shanze
2015-01-01
Managing and identifying the sources of anthropogenic stress in coastal wetlands requires an in-depth understanding of relationships between species diversity and human activities. Empirical and experimental studies provide clear evidence that coastal reclamation can have profound impacts on marine organisms, but the focus of such studies is generally on comparative or laboratory research. We developed a compound intensity index (reclamation intensity index, RI) on hybrid coastal reclamation, to quantify the impacts of reclamation on coastal ecosystems. We also made use of mean annual absolute changes to a number of biotic variables (biodiversity, species richness, biomass of total macrozoobenthos, and species richness and biomass of Polychaeta, Mollusca, Crustacea, and Echinodermata) to determine Hedges’d index, which is a measure of the potential effects of coastal reclamation. Our results showed that there was significant difference of coastal reclamation intensity between Yellow Sea, East China Sea and South China Sea, the biological changes in effect sizes of the three regions differed greatly over time. Our modelling analyses showed that hybrid coastal reclamation generally had significant negative impacts on species diversity and biomass of macrozoobenthos. These relationships varied among different taxonomic groups and included both linear and nonlinear relationships. The results indicated that a high-intensity of coastal reclamation contributed to a pronounced decline in species diversity and biomass, while lower-intensity reclamation, or reclamation within certain thresholds, resulted in a small increase in species diversity and biomass. These results have important implications for biodiversity conservation and the ecological restoration of coastal wetlands in face of the intensive reclamation activities.
The effect of luminous intensity on the attraction of phlebotomine sand flies to light traps.
Lima-Neto, Abdias R; Costa-Neta, Benedita M; da Silva, Apoliana Araújo; Brito, Jefferson M; Aguiar, João V C; Ponte, Islana S; Silva, Francinaldo S
2018-05-04
To improve the efficiency of light traps in collecting phlebotomine sand flies, the potential effects of luminous intensity on the attraction of these insects to traps were evaluated. Sand flies were collected with Hooper Pugedo (HP) light traps fitted with 5-mm light-emitting diodes (LED) bulbs: green (520 nm wavelength-10,000, 15,000 and 20,000 millicandela (mcd) and blue (470 nm-4,000, 12,000 and 15,000 mcd). A total of 3,264 sand flies comprising 13 species were collected. The collected species were Lutzomyia longipalpis (Lutz & Neiva) (Diptera: Psychodidae) (52.48%), Evandromyia evandroi (Costa Lima & Antunes, 1939) (Diptera: Psychodidae) (32.90%) and Micropygomyia goiana (Martins, Falcão, & Silva) (Diptera: Psychodidae) (9.76%). An increase in luminous intensity of the LEDs increased the size of the sand fly catch. The lower luminous intensity of green (10,000 mcd) attracted an average of 13.7 ± 2.8 sand flies/trap per night and the other luminous intensities accounted for a mean of 24.1 ± 4.0 (15,000 mcd) and 28.2 ± 5.0 (20,000 mcd) sand flies/trap per night. Regarding the blue wavelength, the lower luminous intensity (4,000 mcd) attracted an average of 27.4 ± 4.1 sand flies/trap per night, followed by 12,000 mcd (37.6 ± 8.7) and 15,000 mcd (40.5 ± 7.3). Based on our data, the luminous intensity of light traps should be considered when developing light traps for monitoring or controlling phlebotomine sand flies.
Intensity limits of the PSI Injector II cyclotron
NASA Astrophysics Data System (ADS)
Kolano, A.; Adelmann, A.; Barlow, R.; Baumgarten, C.
2018-03-01
We investigate limits on the current of the PSI Injector II high intensity separate-sector isochronous cyclotron, in its present configuration and after a proposed upgrade. Accelerator Driven Subcritical Reactors, neutron and neutrino experiments, and medical isotope production all benefit from increases in current, even at the ∼ 10% level: the PSI cyclotrons provide relevant experience. As space charge dominates at low beam energy, the injector is critical. Understanding space charge effects and halo formation through detailed numerical modelling gives clues on how to maximise the extracted current. Simulation of a space-charge dominated low energy high intensity (9.5 mA DC) machine, with a complex collimator set up in the central region shaping the bunch, is not trivial. We use the OPAL code, a tool for charged-particle optics calculations in large accelerator structures and beam lines, including 3D space charge. We have a precise model of the present (production) Injector II, operating at 2.2 mA current. A simple model of the proposed future (upgraded) configuration of the cyclotron is also investigated. We estimate intensity limits based on the developed models, supported by fitted scaling laws and measurements. We have been able to perform more detailed analysis of the bunch parameters and halo development than any previous study. Optimisation techniques enable better matching of the simulation set-up with Injector II parameters and measurements. We show that in the production configuration the beam current scales to the power of three with the beam size. However, at higher intensities, 4th power scaling is a better fit, setting the limit of approximately 3 mA. Currents of over 5 mA, higher than have been achieved to date, can be produced if the collimation scheme is adjusted.
NASA Astrophysics Data System (ADS)
Goyenola, Guillermo; Meerhof, Mariane; Teixeira de Mello, Franco; González-Bergonzoni, Ivan; Graeber, Daniel; Vidal, Nicolas; Mazzeo, Nestor; Ovesen, Niels; Jeppesen, Erik; Thodsen, Hans; Kronvang, Brian
2014-05-01
Climate is changing towards more extreme conditions all over the world. At the same time, land use is becoming more intensive worldwide and particularly in many developing countries, whereas several developed countries are trying to reduce the impacts of intensive agricultural production and lower the excessive nutrient loading and eutrophication symptoms in water bodies. In 2009, we initiated a comparative research project between the subtropical region (Uruguay) and the temperate region (Denmark) to compare the hydrology and nutrient fluxes in paired micro-catchments with extensive production or intensive agriculture. The four selected streams drained catchments of similar size (7 to 19 km2). We have established similarly equipped monitoring stations in the four micro-catchments in spring (November 2009, Uruguay; March 2010, Denmark) to monitor the effects of land use and agriculture intensity on stream hydrology and nutrient concentrations and fluxes under different climate conditions. We have conducted high frequency measurements in the four lowland streams with underwater probes (turbidity, pH, conductivity and oxygen measured every 15 minutes), fortnight grab sampling of water and automatic sampling of composite water samples for nutrient analysis (total and dissolved nitrogen and phosphorus; sampled every four hours and accumulated fortnightly). Moreover, water level and meteorological information (precipitation, air temperature, global radiation, humidity) has been recorded every 10 minutes and instantaneous flow measurements have been conducted at regular intervals, to facilitate the calculation of instantaneous discharge from continuous records of water level (stage-discharge relationships). We will show results of ca. 2 years from this comparative study between Uruguay and Denmark, and the importance of differences in climate and land use will be discussed.
Watts, Christopher R
2016-01-01
Reduced vocal intensity is a core impairment of hypokinetic dysarthria in Parkinson's disease (PD). Speech treatments have been developed to rehabilitate the vocal subsystems underlying this impairment. Intensive treatment programs requiring high-intensity voice and speech exercises with clinician-guided prompting and feedback have been established as effective for improving vocal function. Less is known, however, regarding long-term outcomes of clinical benefit in speakers with PD who receive these treatments. A retrospective cohort design was utilized. Data from 78 patient files across a three year period were analyzed. All patients received a structured, intensive program of voice therapy focusing on speaking intent and loudness. The dependent variable for all analyses was vocal intensity in decibels (dBSPL). Vocal intensity during sustained vowel production, reading, and novel conversational speech was compared at pre-treatment, post-treatment, six month follow-up, and twelve month follow-up periods. Statistically significant increases in vocal intensity were found at post-treatment, 6 months, and 12 month follow-up periods with intensity gains ranging from 5 to 17 dB depending on speaking condition and measurement period. Significant treatment effects were found in all three speaking conditions. Effect sizes for all outcome measures were large, suggesting a strong degree of practical significance. Significant increases in vocal intensity measured at 6 and 12 moth follow-up periods suggested that the sample of patients maintained treatment benefit for up to a year. These findings are supported by outcome studies reporting treatment outcomes within a few months post-treatment, in addition to prior studies that have reported long-term outcome results. The positive treatment outcomes experienced by the PD cohort in this study are consistent with treatment responses subsequent to other treatment approaches which focus on high-intensity, clinician guided motor learning for voice and speech production in PD. Theories regarding the underlying neurophysiological response to treatment will be discussed.
NASA Astrophysics Data System (ADS)
Pla-Sentís, Ildefonso; Nacci, Silvana
2010-05-01
Rainfall simulation has been used as a practical tool for evaluating the interaction of falling water drops on the soil surface, to measure both stability of soil aggregates to drop impact and water infiltration rates. In both cases it is tried to simulate the effects of natural rainfall, which usually occurs at very different, variable and erratic rates and intensities. One of the main arguments against the use of rainfall simulators is the difficulty to reproduce the size, final velocity and kinetic energy of the drops in natural rainfall. Since the early 70´s we have been developing and using different kinds of rainfall simulators, both at laboratory and field levels, and under tropical and Mediterranean soil and climate conditions, in flat and sloping lands. They have been mainly used to evaluate the relative effects of different land use and management, including different cropping systems, tillage practices, surface soil conditioning, surface covers, etc. on soil water infiltration, on runoff and on erosion. Our experience is that in any case it is impossible to reproduce the variable size distribution and terminal velocity of raindrops, and the variable changes in intensity of natural storms, under a particular climate condition. In spite of this, with the use of rainfall simulators it is possible to obtain very good information, which if it is properly interpreted in relation to each particular condition (land and crop management, rainfall characteristics, measurement conditions, etc.) may be used as one of the parameters for deducing and modelling soil water balance and soil moisture regime under different land use and management and variable climate conditions. Due to the possibility for a better control of the intensity of simulated rainfall and of the size of water drops, and the possibility to make more repeated measurements under very variable soil and land conditions, both in the laboratory and specially in the field, the better results have been obtained with small size 500-1000 cm2, easily dismantled, drop former simulators, than with larger, nozzle, or more sophisticated equipments. In this contribution there are presented some of the rainfall simulators developed and used by the main author, and some of the results obtained in different studies of practical problems under tropical and Mediterranean conditions. References Pla, I.,G.Campero, y R.Useche.1974.Physical degradación of agricultural soils in the Western Plains of Venezuela. "Trans.10th Int.Cong.Soil.Sci.Soc". 1:231-240. .Moscú Pla, I. 1975.Effects of bitumen emulsion and polyacrilamide on some physical properties of Venezuelan soils. En "Soil Sci. Soc. Am. Special Publication"• 7. 35-46. Madison. Wisconsin . (USA). Pla, I. 1977.Aggregate size and erosion control on sloping land treated with hydrophobic bitumen emulsion."Soil Conservation and Management in the Humid Tropics".109-115. John Wiley & Sons. Pla, I.1981.Simuladores de lluvia para el estudio de relaciones suelo-agua bajo agricultura de secano en los trópicos. Rev. Fac. Agron. XII(1-2):81-93.Maracay (Venezuela) Pla, I. 1986.A routine laboratory index to predict the effects of soil sealing on soil and water conservation. En "Assesment of Soil Surface Sealing and Crusting". 154-162.State Univ. of Ghent.Gante (Bélgica Pla, I., M.C. Ramos, S. Nacci, F. Fonseca y X. Abreu. 2005. Soil moisture regime in dryland vineyards of Catalunya (Spain) as influenced by climate, soil and land management. "Integrated Soil and Water Management for Orchard Development". FAO Land and Water Bulletin 10. 41-49. Roma (Italia).
Extinction of the soleus H reflex induced by conditioning stimulus given after test stimulus.
Hiraoka, Koichi
2002-02-01
To quantify the extinction of the soleus H reflex induced by a conditioning stimulus above the motor threshold to the post-tibial nerve applied 10-12 ms after a test stimulus (S2 method). Ten healthy subjects participated. The sizes of extinction induced by a test stimulus above the motor threshold (conventional method) and by the S2 method were measured. The size of the conditioned H reflex decreased as the intensity of the S2 conditioning stimulus increased. The decrease was less than that induced by the conventional method. The difference between the two methods correlated highly with the amount of orthodromically activated recurrent inhibition. When the S2 conditioning stimulus evoked an M wave that was roughly half of the maximum M wave, the decrease in the size of the conditioned H reflex depended on the size of the unconditioned H reflex. The S2 method allows us to observe extinction without changing the intensity of the test stimulus. The amount of the extinction depends partially on the size of the unconditioned H reflex. The difference in the sizes of extinction between the S2 and conventional methods should relate to recurrent inhibition.
Inequalities in body size among mermithid nematodes parasitizing earwigs.
Maure, Fanny; Poulin, Robert
2016-12-01
Variation among body sizes of adult parasitic worms determines the relative genetic contribution of individuals to the next generation as it affects the effective parasite population size. Here, we investigate inequalities in body size and how they are affected by intensity of infection in Mermis nigrescens (Mermithidae: Nematoda) parasitizing the European earwig Forficula auricularia in New Zealand. Among a population of pre-adult worms prior to their emergence from the host, we observed only modest inequalities in body length; however, among worms sharing the same individual host, inequalities in body sizes decreased with increasing intensity of infection. Thus, the more worms occurred in a host, the more the second-longest, third-longest and even fourth-longest worms approached the longest worm in body length. This pattern, also known from another mermithid species, suggests that worms sharing the same host may have infected it roughly simultaneously, when the host encountered a clump of eggs in the environment. Thus, the life history and mode of infection of the parasite may explain the modest inequalities in the sizes achieved by pre-adult worms, which are lower than those reported for endoparasitic helminths of vertebrates.
A Systems Approach to Scalable Transportation Network Modeling
DOE Office of Scientific and Technical Information (OSTI.GOV)
Perumalla, Kalyan S
2006-01-01
Emerging needs in transportation network modeling and simulation are raising new challenges with respect to scal-ability of network size and vehicular traffic intensity, speed of simulation for simulation-based optimization, and fidel-ity of vehicular behavior for accurate capture of event phe-nomena. Parallel execution is warranted to sustain the re-quired detail, size and speed. However, few parallel simulators exist for such applications, partly due to the challenges underlying their development. Moreover, many simulators are based on time-stepped models, which can be computationally inefficient for the purposes of modeling evacuation traffic. Here an approach is presented to de-signing a simulator with memory andmore » speed efficiency as the goals from the outset, and, specifically, scalability via parallel execution. The design makes use of discrete event modeling techniques as well as parallel simulation meth-ods. Our simulator, called SCATTER, is being developed, incorporating such design considerations. Preliminary per-formance results are presented on benchmark road net-works, showing scalability to one million vehicles simu-lated on one processor.« less
Powder Injection Molding for mass production of He-cooled divertor parts
NASA Astrophysics Data System (ADS)
Antusch, S.; Norajitra, P.; Piotter, V.; Ritzhaupt-Kleissl, H.-J.
2011-10-01
A He-cooled divertor for future fusion power plants has been developed at KIT. Tungsten and tungsten alloys are presently considered the most promising materials for functional and structural divertor components. The advantages of tungsten materials lie, e.g. in the high melting point, and low activation, the disadvantages are high hardness and brittleness. The machinig of tungsten, e.g. milling, is very complex and cost-intensive. Powder Injection Molding (PIM) is a method for cost effective mass production of near-net-shape parts with high precision. The complete W-PIM process route is outlined and, results of product examination discussed. A binary tungsten powder feedstock with a grain size distribution in the range 0.7-1.7 μm FSSS, and a solid load of 50 vol.% was developed. After heat treatment, the successfully finished samples showed promising results, i.e. 97.6% theoretical density, a grain size of approximately 5 μm, and a hardness of 457 HV0.1.
Boundary Dpp promotes growth of medial and lateral regions of the Drosophila wing
Barrio, Lara; Milán, Marco
2017-01-01
The gradient of Decapentaplegic (Dpp) in the Drosophila wing has served as a paradigm to characterize the role of morphogens in regulating patterning. However, the role of this gradient in regulating tissue size is a topic of intense debate as proliferative growth is homogenous. Here, we combined the Gal4/UAS system and a temperature-sensitive Gal80 molecule to induce RNAi-mediated depletion of dpp and characterise the spatial and temporal requirement of Dpp in promoting growth. We show that Dpp emanating from the AP compartment boundary is required throughout development to promote growth by regulating cell proliferation and tissue size. Dpp regulates growth and proliferation rates equally in central and lateral regions of the developing wing appendage and reduced levels of Dpp affects similarly the width and length of the resulting wing. We also present evidence supporting the proposal that graded activity of Dpp is not an absolute requirement for wing growth. DOI: http://dx.doi.org/10.7554/eLife.22013.001 PMID:28675372
Ramírez-Ponce, Andrés; Garfias-Lozano, Gabriela; Contreras-Ramos, Atilano
2017-01-01
The origin and function of exaggerated traits exhibited by a great number of species with sexual dimorphism remain largely unexplored. The usual model considered as the evolutionary mechanism for the development of these structures is sexual selection. The nature of growth of the postocular flange (POF) in three species of the dobsonfly genus Platyneuromus (Megaloptera, Corydalidae, Corydalinae) is analyzed to explore sexual size dimorphism and allometric scaling. Results involve positive allometry of POF in males of two species, and negative allometry in males of one species, in general with a female-biased sexual dimorphism. We suggest an ancestral condition of dual incipient ornamentation in Platyneuromus, with a subsequent departure of size and shape of POF in males, triggered by sexual selection. Different sexual selection intensities may explain the parallel or divergent growth of POF within the scheme of dual ornamentation. Empirical behavioral data as well as a phylogenetic framework are necessary to clarify possible causes of phenotypic development, time of origin, and evolution of the POF.
Automated mango fruit assessment using fuzzy logic approach
NASA Astrophysics Data System (ADS)
Hasan, Suzanawati Abu; Kin, Teoh Yeong; Sauddin@Sa'duddin, Suraiya; Aziz, Azlan Abdul; Othman, Mahmod; Mansor, Ab Razak; Parnabas, Vincent
2014-06-01
In term of value and volume of production, mango is the third most important fruit product next to pineapple and banana. Accurate size assessment of mango fruits during harvesting is vital to ensure that they are classified to the grade accordingly. However, the current practice in mango industry is grading the mango fruit manually using human graders. This method is inconsistent, inefficient and labor intensive. In this project, a new method of automated mango size and grade assessment is developed using RGB fiber optic sensor and fuzzy logic approach. The calculation of maximum, minimum and mean values based on RGB fiber optic sensor and the decision making development using minimum entropy formulation to analyse the data and make the classification for the mango fruit. This proposed method is capable to differentiate three different grades of mango fruit automatically with 77.78% of overall accuracy compared to human graders sorting. This method was found to be helpful for the application in the current agricultural industry.
The high intensity solar cell: Key to low cost photovoltaic power
NASA Technical Reports Server (NTRS)
Sater, B. L.; Goradia, C.
1975-01-01
The design considerations and performance characteristics of the 'high intensity' (HI) solar cell are presented. A high intensity solar system was analyzed to determine its cost effectiveness and to assess the benefits of further improving HI cell efficiency. It is shown that residential sized systems can be produced at less than $1000/kW peak electric power. Due to their superior high intensity performance characteristics compared to the conventional and VMJ cells, HI cells and light concentrators may be the key to low cost photovoltaic power.
Bingemann, Dieter; Allen, Rachel M.
2012-01-01
We describe a statistical method to analyze dual-channel photon arrival trajectories from single molecule spectroscopy model-free to identify break points in the intensity ratio. Photons are binned with a short bin size to calculate the logarithm of the intensity ratio for each bin. Stochastic photon counting noise leads to a near-normal distribution of this logarithm and the standard student t-test is used to find statistically significant changes in this quantity. In stochastic simulations we determine the significance threshold for the t-test’s p-value at a given level of confidence. We test the method’s sensitivity and accuracy indicating that the analysis reliably locates break points with significant changes in the intensity ratio with little or no error in realistic trajectories with large numbers of small change points, while still identifying a large fraction of the frequent break points with small intensity changes. Based on these results we present an approach to estimate confidence intervals for the identified break point locations and recommend a bin size to choose for the analysis. The method proves powerful and reliable in the analysis of simulated and actual data of single molecule reorientation in a glassy matrix. PMID:22837704
Cunha-Barros, M; Van Sluys, M; Vrcibradic, D; Galdino, C A; Hatano, F H; Rocha, C F
2003-08-01
We studied the parasitism by larvae of the chigger mite Eutrombicula alfreddugesi on the lizard community of Restinga de Jurubatiba, Rio de Janeiro State, Southeastern Brazil. We investigated the patterns of infestation (prevalence and intensity) of chigger mites in four sympatric lizards: Tropidurus torquatus, Mabuya agilis, M. macrorhyncha and Cnemidophorus littoralis. All lizards collected were checked for the presence of mites, which were counted under stereomicroscope. We tested the relationship between intensity of infestation and lizard body size for each species using regression analysis. The prevalences and mean intensities (+ one standard deviation) of infestation on each host species were, respectively: 100%; 86.4 + 94.6 in T. torquatus (n = 62); 100%; 20.9 + 9.3 in M. agilis (n = 7); 100%; 11.1 + 13.1 in M. macrorhyncha (n = 12); and 95.2%; 19.1 + 16.8 in C. littoralis (n = 21). Only for C. littoralis did body size significantly affect the intensity of infestation (r = 0.27, p = 0.02). For all lizard species, the body parts where chiggers occurred with the highest intensity were those of skin folds and joint regions.
Falcone, James A.; Stewart, Jana; Sobieszczyk, Steven; Dupree, Jean; McMahon, Gerard; Buell, Gary
2007-01-01
As part of the U.S. Geological Survey National Water-Quality Assessment Program, the effects of urbanization on stream ecosystems have been intensively investigated in six metropolitan areas in the United States. Approximately 30 watersheds in each area, ranging in size from 4 to 560 square kilometers (median is 50 square kilometers), and spanning a development gradient from very low to very high urbanization, were examined near Atlanta, Georgia; Raleigh, North Carolina; Denver, Colorado; Dallas-Fort Worth, Texas; Portland, Oregon; and Milwaukee-Green Bay, Wisconsin. These six studies are a continuation of three previous studies in Boston, Massachusetts; Birmingham, Alabama; and Salt Lake City, Utah. In each study, geographic information system data for approximately 300 variables were assembled to (a) characterize the environmental settings of the areas and (b) establish a consistent multimetric urban intensity index based on locally important land-cover, infrastructure, and socioeconomic variables. This paper describes the key features of urbanization and the urban intensity index for the study watersheds within each area, how they differ across study areas, and the relation between the environmental setting and the characteristics of urbanization. A number of features of urbanization were identified that correlated very strongly to population density in every study area. Of these, road density had the least variability across diverse geographic settings and most closely matched the multimetric nature of the urban intensity index. A common urban intensity index was derived that ranks watersheds across all six study areas. Differences in local natural settings and urban geography were challenging in (a) identifying consistent urban gradients in individual study areas and (b) creating a common urban intensity index that matched the site scores of the local urban intensity index in all areas. It is intended that the descriptions of the similarities and differences in urbanization and environmental settings across these study areas will provide a foundation for understanding and interpreting the effects of urbanization on stream ecosystems in the studies being conducted as part of the National Water-Quality Assessment Program.
Propagation properties of cylindrical sinc Gaussian beam
NASA Astrophysics Data System (ADS)
Eyyuboğlu, Halil T.; Bayraktar, Mert
2016-09-01
We investigate the propagation properties of cylindrical sinc Gaussian beam in turbulent atmosphere. Since an analytic solution is hardly derivable, the study is carried out with the aid of random phase screens. Evolutions of the beam intensity profile, beam size and kurtosis parameter are analysed. It is found that on the source plane, cylindrical sinc Gaussian beam has a dark hollow appearance, where the side lobes also start to emerge with increase in width parameter and Gaussian source size. During propagation, beams with small width and Gaussian source size exhibit off-axis behaviour, losing the dark hollow shape, accumulating the intensity asymmetrically on one side, whereas those with large width and Gaussian source size retain dark hollow appearance even at long propagation distances. It is seen that the beams with large widths expand more in beam size than the ones with small widths. The structure constant values chosen do not seem to alter this situation. The kurtosis parameters of the beams having small widths are seen to be larger than the ones with the small widths. Again the choice of the structure constant does not change this trend.
Long-term effective population size dynamics of an intensively monitored vertebrate population
Mueller, A-K; Chakarov, N; Krüger, O; Hoffman, J I
2016-01-01
Long-term genetic data from intensively monitored natural populations are important for understanding how effective population sizes (Ne) can vary over time. We therefore genotyped 1622 common buzzard (Buteo buteo) chicks sampled over 12 consecutive years (2002–2013 inclusive) at 15 microsatellite loci. This data set allowed us to both compare single-sample with temporal approaches and explore temporal patterns in the effective number of parents that produced each cohort in relation to the observed population dynamics. We found reasonable consistency between linkage disequilibrium-based single-sample and temporal estimators, particularly during the latter half of the study, but no clear relationship between annual Ne estimates () and census sizes. We also documented a 14-fold increase in between 2008 and 2011, a period during which the census size doubled, probably reflecting a combination of higher adult survival and immigration from further afield. Our study thus reveals appreciable temporal heterogeneity in the effective population size of a natural vertebrate population, confirms the need for long-term studies and cautions against drawing conclusions from a single sample. PMID:27553455
The ESI scale, an ethical approach to the evaluation of seismic hazards
NASA Astrophysics Data System (ADS)
Porfido, Sabina; Nappi, Rosa; De Lucia, Maddalena; Gaudiosi, Germana; Alessio, Giuliana; Guerrieri, Luca
2015-04-01
The dissemination of correct information about seismic hazard is an ethical duty of scientific community worldwide. A proper assessment of a earthquake severity and impact should not ignore the evaluation of its intensity, taking into account both the effects on humans, man-made structures, as well as on the natural evironment. We illustrate the new macroseismic scale that measures the intensity taking into account the effects of earthquakes on the environment: the ESI 2007 (Environmental Seismic Intensity) scale (Michetti et al., 2007), ratified by the INQUA (International Union for Quaternary Research) during the XVII Congress in Cairns (Australia). The ESI scale integrates and completes the traditional macroseismic scales, of which it represents the evolution, allowing to assess the intensity parameter also where buildings are absent or damage-based diagnostic elements saturate. Each degree reflects the corresponding strength of an earthquake and the role of ground effects, evaluating the Intensity on the basis of the characteristics and size of primary (e.g. surface faulting and tectonic uplift/subsidence) and secondary effects (e.g. ground cracks, slope movements, liquefaction phenomena, hydrological changes, anomalous waves, tsunamis, trees shaking, dust clouds and jumping stones). This approach can be considered "ethical" because helps to define the real scenario of an earthquake, regardless of the country's socio-economic conditions and level of development. Here lies the value and the relevance of macroseismic scales even today, one hundred years after the death of Giuseppe Mercalli, who conceived the homonymous scale for the evaluation of earthquake intensity. For an appropriate mitigation strategy in seismic areas, it is fundamental to consider the role played by seismically induced effects on ground, such as active faults (size in length and displacement) and secondary effects (the total area affecting). With these perspectives two different cases studies have been reviewed: the destructive 1976 February 4 Guatemala, earthquake (M 7.5) and the 1743 February 20 Nardò, historical earthquake (Salento, Southern Italy). The re-analysis of both earthquakes contributes to define more realistic seismic scenarios in terms of intensities assessment and consequent regional seismic hazards. References Michetti A.M., Esposito E., Guerrieri L., Porfido S., Serva L., Tatevossian R., Vittori E., Audemard F., Azuma T., Clague J., Comerci V., Gurpinar A., Mccalpin J., Mohammadioun B., Mörner N.A, Ota Y. And E. Roghozin - 2007. Intensity Scale ESI 2007, Mem. Descrittive della Carta Geologica d'Italia, Roma, 74, 53 pp
NASA Astrophysics Data System (ADS)
Nanko, K.; Levia, D. F., Jr.; Iida, S.; SUN, X.; Shinohara, Y.; Sakai, N.
2017-12-01
Scientists have been interested in throughfall drop size and its distribution because of its importance to soil erosion and the forest water balance. An indoor experiment was employed to deepen our understanding of throughfall drop generation processes to promote better management of forested ecosystems. The indoor experiment provides a unique opportunity to examine an array of constant rainfall intensities that are ideal conditions to pick up the effect of changing intensities and not found in the fields. Throughfall drop generation was examined for three species- Cryptomeria japonica D. Don (Japanese cedar), Chamaecyparis obtusa (Siebold & Zucc.) Endl. (Japanese cypress), and Zelkova serrata Thunb. (Japanese zelkova)- under both leafed and leafless conditions in the large-scale rainfall simulator in the National Research Institute for Earth Science and Disaster Resilience (Tsukuba, Japan) at varying rainfall intensities ranging from15 to 100 mm h-1. Drop size distributions of the applied rainfall and throughfall were measured simultaneously by 20 laser disdrometers. Utilizing the drop size dataset, throughfall was separated into three components: free throughfall, canopy drip, and splash throughfall. The temporal sequencing of the throughfall components were analyzed on a 1-min interval during each experimental run. The throughfall component percentage and drop size of canopy drip differed among tree species and rainfall intensities and by elapsed time from the beginning of the rainfall event. Preliminary analysis revealed that the time differences to produce branch drip as compared to leaf (or needle) drip was partly due to differential canopy wet-up processes and the disappearance of branch drips due to canopy saturation, leading to dissimilar throughfall drop size distributions beneath the various tree species examined. This research was supported by JSPS Invitation Fellowship for Research in Japan (Grant No.: S16088) and JSPS KAKENHI (Grant No.: JP15H05626).
Generation of nano-voids inside polylactide using femtosecond laser radiation
NASA Astrophysics Data System (ADS)
Viertel, Tina; Pabst, Linda; Olbrich, Markus; Ebert, Robby; Horn, Alexander; Exner, Horst
2017-12-01
The arrangement of nanometer-sized voids, induced by focusing intense laser radiation within transparent material can allow the generation of transparent components with dimensions in the micrometer to nanometre range due to internal contour cut and thus satisfy the progressive miniaturization of products in micro-optics and medical technologies. For further improvements in the precision of those components, a deep understanding of the involved processes during the interaction of laser radiation within the material is necessary. In this work, voids inside bulk polylactide (PLA), a bioabsorbable polymer, were generated using a femtosecond laser ( λ = 1030 nm, τH = 180 fs) with single and multiple pulse irradiation. The dependence of the spot size was examined by the use of four microscope objectives with focus radii of 4.9, 3.3, 2 and 1.2 µm. For the experiments, the pulse energy and focusing depth into the material were varied. The dimensions of the voids were experimentally determined as function of the intensity. Differences in the lateral and axial extents of the voids were obtained for different focus radii and focusing depths at same intensities. Furthermore, the intensity distribution of the laser radiation inside the material for the different focus radii and focusing depths, and their dependence on the lateral and axial sizes of the voids was simulated and compared with the experimental results.
NASA Astrophysics Data System (ADS)
Jux, Maximilian; Finke, Benedikt; Mahrholz, Thorsten; Sinapius, Michael; Kwade, Arno; Schilde, Carsten
2017-04-01
Several epoxy Al(OH)O (boehmite) dispersions in an epoxy resin are produced in a kneader to study the mechanistic correlation between the nanoparticle size and mechanical properties of the prepared nanocomposites. The agglomerate size is set by a targeted variation in solid content and temperature during dispersion, resulting in a different level of stress intensity and thus a different final agglomerate size during the process. The suspension viscosity was used for the estimation of stress energy in laminar shear flow. Agglomerate size measurements are executed via dynamic light scattering to ensure the quality of the produced dispersions. Furthermore, various nanocomposite samples are prepared for three-point bending, tension, and fracture toughness tests. The screening of the size effect is executed with at least seven samples per agglomerate size and test method. The variation of solid content is found to be a reliable method to adjust the agglomerate size between 138-354 nm during dispersion. The size effect on the Young's modulus and the critical stress intensity is only marginal. Nevertheless, there is a statistically relevant trend showing a linear increase with a decrease in agglomerate size. In contrast, the size effect is more dominant to the sample's strain and stress at failure. Unlike microscaled agglomerates or particles, which lead to embrittlement of the composite material, nanoscaled agglomerates or particles cause the composite elongation to be nearly of the same level as the base material. The observed effect is valid for agglomerate sizes between 138-354 nm and a particle mass fraction of 10 wt%.
Observing Evolutionary Entropy in Relation to Body Size Over Time
NASA Astrophysics Data System (ADS)
Idgunji, S.; Zhang, H.; Payne, J.; Heim, N. A.
2015-12-01
The Second Law of Thermodynamics, according to Clausius, states that entropy will always increase in the universe, meaning systems will break down and become simple and chaotic. However, this is seemingly contradicted by the existence of living organisms, which can have highly complex and organized systems. Furthermore, there is a greater contradiction in the theory of evolution, which sees organisms growing larger and becoming more complex over time. Our research project revolved around whether organisms actually became more complex over time, and correlating these findings with the body size of these organisms. We analyzed the relationship between body size and cell types of five different marine phyla: arthropods, brachiopods, chordates, echinoderms, and mollusks. We attempted to find a relation between the biovolume of these different phyla and the number of specialized cell types that they had, which is a common measure of biocomplexity. In addition, we looked at the metabolic intensity, which is the mass-specific rate of energy processing applied to an organism's size, because it is also correlated to genetic complexity. Using R programming, we tested for correlations between these factors. After applying a Pearson correlation test, we discovered a generally positive correlation between the body sizes, number of cell types, and metabolic intensities of these phyla. However, one exception is that there is a negative correlation between the body size and metabolic intensity of echinoderms. Overall, we can see that marine organisms tend to evolve larger and more complex over time, and that is a very interesting find. Our discovery yielded many research questions and problems that we would like to solve, such as how the environment is thermodynamically affected by these organisms.
Sakamoto, S; Kiger, W S; Harling, O K
1999-09-01
Sensitivity studies of epithermal neutron beam performance in boron neutron capture therapy are presented for realistic neutron beams with varying filter/moderator and collimator/delimiter designs to examine the relative importance of neutron beam spectrum, directionality, and size. Figures of merit for in-air and in-phantom beam performance are calculated via the Monte Carlo technique for different well-optimized designs of a fission converter-based epithermal neutron beam with head phantoms as the irradiation target. It is shown that increasing J/phi, a measure of beam directionality, does not always lead to corresponding monotonic improvements in beam performance. Due to the relatively low significance, for most configurations, of its effect on in-phantom performance and the large intensity losses required to produce beams with very high J/phi, beam directionality should not be considered an important figure of merit in epithermal neutron beam design except in terms of its consequences on patient positioning and collateral dose. Hardening the epithermal beam spectrum, while maintaining the specific fast neutron dose well below the inherent hydrogen capture dose, improves beam penetration and advantage depth and, as a desirable by-product, significantly increases beam intensity. Beam figures of merit are shown to be strongly dependent on beam size relative to target size. Beam designs with J/phi approximately 0.65-0.7, specific fast neutron doses of 2-2.6x10(-13) Gy cm2/n and beam sizes equal to or larger than the size of the head target produced the deepest useful penetration, highest therapeutic ratios, and highest intensities.
NASA Technical Reports Server (NTRS)
Duvoisin, Marc R.; Convertino, Victor A; Buchanan, Paul; Gollinick, Philip D.; Dudley, Gary A.
1989-01-01
During 30 days (d) of bedrest, the practicality of using Elec- troMyoStimulation (EMS) as a deterrent to atrophy and strength loss of lower limb musculature was examined. An EMS system was developed that provided variable but quantifiable levels of EMS, and measured torque. The dominant log of three male subjects was stimulated twice daily in a 3-d on/1-d off cycle during bedrest. The non-dominant leg of each subject acted as a control. A stimulator, using a 0.3 ms monophasic 60 Hz pulse waveform, activated muscle tissue for 4 s. The output waveform from the stimulator was sequenced to the Knee Extensors (KE), Knee Flex- ors (KF), Ankle Extensors (AE), and Ankle Flexors (AF), and caused three isometric contractions of each muscle group per minute. Subject tolerance determined EMS Intensity. Each muscle group received four 5-min bouts of EMS each session with a 10 -min rest between bouts. EMS and torque levels for each muscle action were recorded directly an a computer. Overall average EMS Intensity was 197, 197, 195, and 188 mA for the KE, KF, AF, and AE, respectively. Overall average torque development for these muscle groups was 70, 16, 12, and 27 Nm, respectively. EMS intensity doubled during the study, and average torque increased 2.5 times. Average maximum torque throughout a session reached 54% of maximal voluntary for the KE and 29% for the KF. Reductions in leg volume, muscle compartment size, cross-sectional area of slow and fast-twitch fibers, strength, and aerobic enzyme activities, and increased log compliance were attenuated in the legs which received EMS during bedrest. These results indicate that similar EMS levels induce different torques among different muscle groups and that repeated exposure to EMS increases tolerance and torque development. Longer orien- tation periods, therefore, may enhance its effectiveness. Our preliminary data suggest that the efficacy of EMS as an effective countermeasure for muscle atrophy and strength loss during long duration space travel warrants further investigation.
Intrinsic beam emittance of laser-accelerated electrons measured by x-ray spectroscopic imaging.
Golovin, G; Banerjee, S; Liu, C; Chen, S; Zhang, J; Zhao, B; Zhang, P; Veale, M; Wilson, M; Seller, P; Umstadter, D
2016-04-19
The recent combination of ultra-intense lasers and laser-accelerated electron beams is enabling the development of a new generation of compact x-ray light sources, the coherence of which depends directly on electron beam emittance. Although the emittance of accelerated electron beams can be low, it can grow due to the effects of space charge during free-space propagation. Direct experimental measurement of this important property is complicated by micron-scale beam sizes, and the presence of intense fields at the location where space charge acts. Reported here is a novel, non-destructive, single-shot method that overcame this problem. It employed an intense laser probe pulse, and spectroscopic imaging of the inverse-Compton scattered x-rays, allowing measurement of an ultra-low value for the normalized transverse emittance, 0.15 (±0.06) π mm mrad, as well as study of its subsequent growth upon exiting the accelerator. The technique and results are critical for designing multi-stage laser-wakefield accelerators, and generating high-brightness, spatially coherent x-rays.
Short intense ion pulses for materials and warm dense matter research
Seidl, Peter A.; Persaud, Arun; Waldron, William L.; ...
2015-08-14
We have commenced experiments with intense short pulses of ion beams on the Neutralized Drift Compression Experiment-II at Lawrence Berkeley National Laboratory, by generating beam spots size with radius r<1 mm within 2 ns FWHM and approximately 10 10 ions/pulse. To enable the short pulse durations and mm-scale focal spot radii, the 1.2 MeV Li + ion beam is neutralized in a 1.6-meter drift compression section located after the last accelerator magnet. An 8-Tesla short focal length solenoid compresses the beam in the presence of the large volume plasma near the end of this section before the target. The scientificmore » topics to be explored are warm dense matter, the dynamics of radiation damage in materials, and intense beam and beam-plasma physics including selected topics of relevance to the development of heavy-ion drivers for inertial fusion energy. Finally, we describe the accelerator commissioning and time-resolved ionoluminescence measurements of yttrium aluminum perovskite using the fully integrated accelerator and neutralized drift compression components.« less
Intrinsic beam emittance of laser-accelerated electrons measured by x-ray spectroscopic imaging
Golovin, G.; Banerjee, S.; Liu, C.; ...
2016-04-19
Here, the recent combination of ultra-intense lasers and laser-accelerated electron beams is enabling the development of a new generation of compact x-ray light sources, the coherence of which depends directly on electron beam emittance. Although the emittance of accelerated electron beams can be low, it can grow due to the effects of space charge during free-space propagation. Direct experimental measurement of this important property is complicated by micron-scale beam sizes, and the presence of intense fields at the location where space charge acts. Reported here is a novel, non-destructive, single-shot method that overcame this problem. It employed an intense lasermore » probe pulse, and spectroscopic imaging of the inverse-Compton scattered x-rays, allowing measurement of an ultra-low value for the normalized transverse emittance, 0.15 (±0.06) π mm mrad, as well as study of its subsequent growth upon exiting the accelerator. The technique and results are critical for designing multi-stage laser-wakefield accelerators, and generating high-brightness, spatially coherent x-rays.« less
Cluster mass inference via random field theory.
Zhang, Hui; Nichols, Thomas E; Johnson, Timothy D
2009-01-01
Cluster extent and voxel intensity are two widely used statistics in neuroimaging inference. Cluster extent is sensitive to spatially extended signals while voxel intensity is better for intense but focal signals. In order to leverage strength from both statistics, several nonparametric permutation methods have been proposed to combine the two methods. Simulation studies have shown that of the different cluster permutation methods, the cluster mass statistic is generally the best. However, to date, there is no parametric cluster mass inference available. In this paper, we propose a cluster mass inference method based on random field theory (RFT). We develop this method for Gaussian images, evaluate it on Gaussian and Gaussianized t-statistic images and investigate its statistical properties via simulation studies and real data. Simulation results show that the method is valid under the null hypothesis and demonstrate that it can be more powerful than the cluster extent inference method. Further, analyses with a single subject and a group fMRI dataset demonstrate better power than traditional cluster size inference, and good accuracy relative to a gold-standard permutation test.
Hospital-level changes in adult ICU bed supply in the United States
Wallace, David J.; Seymour, Christopher W.; Kahn, Jeremy M.
2017-01-01
Objective Although the number of intensive care beds in the United States is increasing, little is known about the hospitals responsible for this growth. We sought to better characterize national growth in intensive care beds by identifying hospital-level factors associated with increasing numbers of intensive care beds over time. Design We performed a repeated-measures time series analysis of hospital-level intensive care bed supply using data from Centers for Medicare and Medicaid Services. Setting All United States acute care hospitals with adult intensive care beds over the years 1996 to 2011. Measurements & Main Results We described the number of beds, teaching status, ownership, intensive care occupancy and urbanicity for each hospital in each year of the study. We then examined the relationship between increasing intensive care beds and these characteristics, controlling for other factors. The study included 4,457 hospitals and 55,865 hospital-years. Overall, the majority of intensive care bed growth occurred in teaching hospitals (net +13,471 beds, 72.1% of total growth), hospitals with 250 or more beds (net +18,327 beds, 91.8% of total growth) and hospitals in the highest quartile of occupancy (net +10,157 beds, 54.0% of total growth). In a longitudinal multivariable model, larger hospital size, teaching status, and high intensive care occupancy were associated with subsequent-year growth. Furthermore, the effects of hospital size and teaching status were modified by occupancy: the greatest odds of increasing intensive care unit beds were in hospitals with 500 or more beds in the highest quartile of occupancy (adjusted OR: 18.9; 95% CI: 14.0 – 25.5; p<0.01) and large teaching hospitals in the highest quartile of occupancy (adjusted OR: 7.3; 95% CI: 5.3 – 9.9; p<0.01). Conclusions Increasingly, intensive care bed expansion in the United States is occurring in larger hospitals and teaching centers, particularly following a year with high intensive care unit occupancy. PMID:27661861
NASA/FLAGRO - FATIGUE CRACK GROWTH COMPUTER PROGRAM
NASA Technical Reports Server (NTRS)
Forman, R. G.
1994-01-01
Structural flaws and cracks may grow under fatigue inducing loads and, upon reaching a critical size, cause structural failure to occur. The growth of these flaws and cracks may occur at load levels well below the ultimate load bearing capability of the structure. The Fatigue Crack Growth Computer Program, NASA/FLAGRO, was developed as an aid in predicting the growth of pre-existing flaws and cracks in structural components of space systems. The earlier version of the program, FLAGRO4, was the primary analysis tool used by Rockwell International and the Shuttle subcontractors for fracture control analysis on the Space Shuttle. NASA/FLAGRO is an enhanced version of the program and incorporates state-of-the-art improvements in both fracture mechanics and computer technology. NASA/FLAGRO provides the fracture mechanics analyst with a computerized method of evaluating the "safe crack growth life" capabilities of structural components. NASA/FLAGRO could also be used to evaluate the damage tolerance aspects of a given structural design. The propagation of an existing crack is governed by the stress field in the vicinity of the crack tip. The stress intensity factor is defined in terms of the relationship between the stress field magnitude and the crack size. The propagation of the crack becomes catastrophic when the local stress intensity factor reaches the fracture toughness of the material. NASA/FLAGRO predicts crack growth using a two-dimensional model which predicts growth independently in two directions based on the calculation of stress intensity factors. The analyst can choose to use either a crack growth rate equation or a nonlinear interpolation routine based on tabular data. The growth rate equation is a modified Forman equation which can be converted to a Paris or Walker equation by substituting different values into the exponent. This equation provides accuracy and versatility and can be fit to data using standard least squares methods. Stress-intensity factor numerical values can be computed for making comparisons or checks of solutions. NASA/FLAGRO can check for failure of a part-through crack in the mode of a through crack when net ligament yielding occurs. NASA/FLAGRO has a number of special subroutines and files which provide enhanced capabilities and easy entry of data. These include crack case solutions, cyclic load spectrums, nondestructive examination initial flaw sizes, table interpolation, and material properties. The materials properties files are divided into two types, a user defined file and a fixed file. Data is entered and stored in the user defined file during program execution, while the fixed file contains already coded-in property value data for many different materials. Prompted input from CRT terminals consists of initial crack definition (which can be defined automatically), rate solution type, flaw type and geometry, material properties (if they are not in the built-in tables of material data), load spectrum data (if not included in the loads spectrum file), and design limit stress levels. NASA/FLAGRO output includes an echo of the input with any error or warning messages, the final crack size, whether or not critical crack size has been reached for the specified stress level, and a life history profile of the crack propagation. NASA/FLAGRO is modularly designed to facilitate revisions and operation on minicomputers. The program was implemented on a DEC VAX 11/780 with the VMS operating system. NASA/FLAGRO is written in FORTRAN77 and has a memory requirement of 1.4 MB. The program was developed in 1986.
NASA Astrophysics Data System (ADS)
Sengbusch, Evan R.
Physical properties of proton interactions in matter give them a theoretical advantage over photons in radiation therapy for cancer treatment, but they are seldom used relative to photons. The primary barriers to wider acceptance of proton therapy are the technical feasibility, size, and price of proton therapy systems. Several aspects of the proton therapy landscape are investigated, and new techniques for treatment planning, optimization, and beam delivery are presented. The results of these investigations suggest a means by which proton therapy can be delivered more efficiently, effectively, and to a much larger proportion of eligible patients. An analysis of the existing proton therapy market was performed. Personal interviews with over 30 radiation oncology leaders were conducted with regard to the current and future use of proton therapy. In addition, global proton therapy market projections are presented. The results of these investigations serve as motivation and guidance for the subsequent development of treatment system designs and treatment planning, optimization, and beam delivery methods. A major factor impacting the size and cost of proton treatment systems is the maximum energy of the accelerator. Historically, 250 MeV has been the accepted value, but there is minimal quantitative evidence in the literature that supports this standard. A retrospective study of 100 patients is presented that quantifies the maximum proton kinetic energy requirements for cancer treatment, and the impact of those results with regard to treatment system size, cost, and neutron production is discussed. This study is subsequently expanded to include 100 cranial stereotactic radiosurgery (SRS) patients, and the results are discussed in the context of a proposed dedicated proton SRS treatment system. Finally, novel proton therapy optimization and delivery techniques are presented. Algorithms are developed that optimize treatment plans over beam angle, spot size, spot spacing, beamlet weight, the number of delivered beamlets, and the number of delivery angles. These methods are evaluated via treatment planning studies including left-sided whole breast irradiation, lung stereotactic body radiotherapy, nasopharyngeal carcinoma, and whole brain radiotherapy with hippocampal avoidance. Improvements in efficiency and efficacy relative to traditional proton therapy and intensity modulated photon radiation therapy are discussed.
Zhang, Xiaoyan; Li, Caixia; Gong, Zhiyuan
2014-01-01
Previously we have developed a transgenic zebrafish line (LiPan) with liver-specific red fluorescent protein (DsRed) expression under the fabp10a promoter. Since red fluorescence in the liver greatly facilitates the observation of liver in live LiPan fry, we envision that the LiPan zebrafish may provide a useful tool in analyses of hepatotoxicity based on changes of liver red fluorescence intensity and size. In this study, we first tested four well-established hepatotoxins (acetaminophen, aspirin, isoniazid and phenylbutazone) in LiPan fry and demonstrated that these hepatotoxins could significantly reduce both liver red fluorescence and liver size in a dosage-dependent manner, thus the two measurable parameters could be used as indicators of hepatotoxicity. We then tested the LiPan fry with nine other chemicals including environmental toxicants and human drugs. Three (mefenamic acid, lindane, and arsenate) behave like hepatotoxins in reduction of liver red fluorescence, while three others (17β-estradiol, TCDD [2,3,7,8-tetrachlorodibenzo-p-dioxin] and NDMA [N-nitrosodimethylamine]) caused increase of liver red fluorescence and the liver size. Ethanol and two other chemicals, amoxicillin (antibiotics) and chlorphenamine (pain killer) did not resulted in significant changes of liver red fluorescence and liver size. By quantitative RT-PCR analysis, we found that the changes of red fluorescence intensity caused by different chemicals correlated to the changes of endogenous fabp10a RNA expression, indicating that the measured hepatotoxicity was related to fatty acid transportation and metabolism. Finally we tested a mixture of four hepatotoxins and observed a significant reduction of red fluorescence in the liver at concentrations below the lowest effective concentrations of individual hepatotoxins, suggesting that the transgenic zebrafish assay is capable of reporting compound hepatotoxicity effect from chemical mixtures. Thus, the LiPan transgenic fry provide a rapid and convenient in vivo hepatotoxicity assay that should be applicable to high-throughput hepatotoxicity test in drug screening as well as in biomonitoring environmental toxicants. PMID:24626481
Measurement of bow tie profiles in CT scanners using a real-time dosimeter
DOE Office of Scientific and Technical Information (OSTI.GOV)
Whiting, Bruce R., E-mail: whitingbrucer@gmail.com; Evans, Joshua D.; Williamson, Jeffrey F.
2014-10-15
Purpose: Several areas of computed tomography (CT) research require knowledge about the intensity profile of the x-ray fan beam that is introduced by a bow tie filter. This information is considered proprietary by CT manufacturers, so noninvasive measurement methods are required. One method using real-time dosimeters has been proposed in the literature. A commercially available dosimeter was used to apply that method, and analysis techniques were developed to extract fan beam profiles from measurements. Methods: A real-time ion chamber was placed near the periphery of an empty CT gantry and the dose rate versus time waveform was recorded as themore » x-ray source rotated about the isocenter. In contrast to previously proposed analysis methods that assumed a pointlike detector, the finite-size ion chamber received varying amounts of coverage by the collimated x-ray beam during rotation, precluding a simple relationship between the source intensity as a function of fan beam angle and measured intensity. A two-parameter model for measurement intensity was developed that included both effective collimation width and source-to-detector distance, which then was iteratively solved to minimize the error between duplicate measurements at corresponding fan beam angles, allowing determination of the fan beam profile from measured dose-rate waveforms. Measurements were performed on five different scanner systems while varying parameters such as collimation, kVp, and bow tie filters. On one system, direct measurements of the bow tie profile were collected for comparison with the real-time dosimeter technique. Results: The data analysis method for a finite-size detector was found to produce a fan beam profile estimate with a relative error between duplicate measurement intensities of <5%. It was robust over a wide range of collimation widths (e.g., 1–40 mm), producing fan beam profiles that agreed with a relative error of 1%–5%. Comparison with a direct measurement technique on one system produced agreement with a relative error of 2%–6%. Fan beam profiles were found to differ for different filter types on a given system and between different vendors. Conclusions: A commercially available real-time dosimeter probe was found to be a convenient and accurate instrument for measuring fan beam profiles. An analysis method was developed that could handle a wide range of collimation widths by explicitly considering the finite width of the ion chamber. Relative errors in the profiles were found to be less than 5%. Measurements of five different clinical scanners demonstrate the variation in bow tie designs, indicating that generic bow tie models will not be adequate for CT system research.« less
Influence of local meshing size on stress intensity factor of orthopedic lag screw
NASA Astrophysics Data System (ADS)
Husain, M. N.; Daud, R.; Basaruddin, K. S.; Mat, F.; Bajuri, M. Y.; Arifin, A. K.
2017-09-01
Linear elastic fracture mechanics (LEFM) concept is generally used to study the influence of crack on the performance of structures. In order to study the LEFM concept on damaged structure, the usage of finite element analysis software is implemented to do the simulation of the structure. Mesh generation is one of the most crucial procedures in finite element method. For the structure that crack or damaged, it is very important to determine the accurate local meshing size at the crack tip of the crack itself in order to get the accurate value of stress intensity factor, KI. Pre crack will be introduced to the lag screw based on the von mises' stress result that had been performed in previous research. This paper shows the influence of local mesh arrangement on numerical value of the stress intensity factor, KI obtained by the displacement method. This study aims to simulate the effect of local meshing which is the singularity region on stress intensity factor, KI to the critical point of failure in screw. Five different set of wedges meshing size are introduced during the simulation of finite element analysis. The number of wedges used to simulate this research is 8, 10, 14, 16 and 20. There are three set of numerical equations used to validate the results which are brown and srawley, gross and brown and Tada equation. The result obtained from the finite element software (ANSYS APDL) has a positive agreement with the numerical analysis which is Brown and Srawley compared to other numerical formula. Radius of first row size of 0.014 and singularity element with 14 numbers of wedges is proved to be the best local meshing for this study.
Development, characterization and in vivo evaluation of benzocaine-loaded liposomes.
Mura, Paola; Maestrelli, Francesca; González-Rodríguez, Maria Luisa; Michelacci, Ilaria; Ghelardini, Carla; Rabasco, Antonio M
2007-08-01
This study reports the development and in vivo evaluation of a liposomal formulation of the local anaesthetic benzocaine. Multi-lamellar (MLV) and small uni-lamellar (SUV) vesicles entrapping benzocaine were prepared using 50:50 w/w phosphatidylcholine-cholesterol as lipophilic phase and 50:50 v/v ethanol-water as hydrophilic phase. Liposome size, Zeta-potential, encapsulation efficiency and skin penetration properties were determined. Drug permeation from liposomal dispersions, as such or formulated in Carbopol gel, was evaluated through artificial lipophilic membranes and excised abdominal rat skin, whereas in vivo anaesthetic effect was tested on rabbits. Interestingly, addition of the drug into the hydrophilic phase, rather than into the lipophilic one, during liposome preparation enabled an improvement of the MLV's entrapment efficiency from 29.7% to 82.3%. On the other hand, sonication conditions to obtain SUV influenced size and polydispersity index of the vesicles and reduced the entrapment efficiency by about 30%. All liposomal-benzocaine formulations showed sustained release properties and a more intense anaesthetic effect than plain drug. Permeation experiments from drug solutions in gel containing the same amount of ethanol as in the liposomal formulations made it possible to exclude a possible enhancer effect of this solvent, at least when not used in liposomal formulations. MLV with the drug added into the hydrophilic phase gave the most effective formulation, showing a permeability coefficient value 2.5 times higher than that of the plain drug and allowing a significant improvement (P<0.01) not only of intensity but also of duration of anaesthetic effect of benzocaine. These results suggest that a suitably developed liposomal formulation of benzocaine can be of actual value for improving its clinical effectiveness in topical anaesthesia.
NASA Astrophysics Data System (ADS)
Jaiswal, Neeru; Ha, Doan Thi Thu; Kishtawal, C. M.
2018-03-01
Tropical cyclone (TC) is one of the most intense weather hazards, especially for the coastal regions, as it causes huge devastation through gale winds and torrential floods during landfall. Thus, accurate prediction of TC is of great importance to reduce the loss of life and damage to property. Most of the cyclone track prediction model requires size of TC as an important parameter in order to simulate the vortex. TC size is also required in the impact assessment of TC affected regions. In the present work, the size of TCs formed in the North Indian Ocean (NIO) has been estimated using the high resolution surface wind observations from oceansat-2 scatterometer. The estimated sizes of cyclones were compared to the radius of outermost closed isobar (ROCI) values provided by Joint Typhoon warning Center (JTWC) by plotting their histograms and computing the correlation and mean absolute error (MAE). The correlation and MAE between the OSCAT wind based TC size estimation and JTWC-ROCI values was found 0.69 and 33 km, respectively. The results show that the sizes of cyclones estimated by OSCAT winds are in close agreement to the JTWC-ROCI. The ROCI values of JTWC were analyzed to study the variations in the size of tropical cyclones in NIO during different time of the diurnal cycle and intensity stages.
Reduced clot debris size using standing waves formed via high intensity focused ultrasound
NASA Astrophysics Data System (ADS)
Guo, Shifang; Du, Xuan; Wang, Xin; Lu, Shukuan; Shi, Aiwei; Xu, Shanshan; Bouakaz, Ayache; Wan, Mingxi
2017-09-01
The feasibility of utilizing high intensity focused ultrasound (HIFU) to induce thrombolysis has been demonstrated previously. However, clinical concerns still remain related to the clot debris produced via fragmentation of the original clot potentially being too large and hence occluding downstream vessels, causing hazardous emboli. This study investigates the use of standing wave fields formed via HIFU to disintegrate the thrombus while achieving a reduced clot debris size in vitro. The results showed that the average diameter of the clot debris calculated by volume percentage was smaller in the standing wave mode than in the travelling wave mode at identical ultrasound thrombolysis settings. Furthermore, the inertial cavitation dose was shown to be lower in the standing wave mode, while the estimated cavitation bubble size distribution was similar in both modes. These results show that a reduction of the clot debris size with standing waves may be attributed to the particle trapping of the acoustic potential well which contributed to particle fragmentation.
Johnson, J. H.; Nack, C.C.
2010-01-01
We examined feeding periodicity of three size groups of the rusty crayfish (Orconectes rusticus) at four-hour intervals over a 28-hour period during July in a headwater stream of the Susquehanna River drainage in central New York. Feeding activity was expressed as the ratio of stomach weight divided by the crayfish wet weight. The diel food consumption patterns of all three size groups of rusty crayfish (i.e., ??? 10 mm, 11-20 mm, and > 20 mm carapace length) were significantly different. Peak feeding of the smallest crayfish occurred during crepuscular periods. Food consumption of the intermediate size crayfish was highest at 2000 h, and feeding of large crayfish was consistently high from 1200 h to 0400 h. Feeding intensity of both small and intermediate size crayfish was highest when feeding intensity of large crayfsh was lowest. Ontogenetic differences in feeding periodicity may be associated with predation pressure from large rusty crayfish on smaller individuals.
Johnson, James H.; Nack, Christopher C.
2010-01-01
We examined feeding periodicity of three size groups of the rusty crayfish (Orconectes rusticus) at four-hour intervals over a 28-hour period during July in a headwater stream of the Susquehanna River drainage in central New York. Feeding activity was expressed as the ratio of stomach weight divided by the crayfish wet weight. The diel food consumption patterns of all three size groups of rusty crayfish (i.e., ≤ 10 mm, 11–20 mm, and > 20 mm carapace length) were significantly different. Peak feeding of the smallest crayfish occurred during crepuscular periods. Food consumption of the intermediate size crayfish was highest at 2000 h, and feeding of large crayfish was consistently high from 1200 h to 0400 h. Feeding intensity of both small and intermediate size crayfish was highest when feeding intensity of large crayfsh was lowest. Ontogenetic differences in feeding periodicity may be associated with predation pressure from large rusty crayfish on smaller individuals.
Function combined method for design innovation of children's bike
NASA Astrophysics Data System (ADS)
Wu, Xiaoli; Qiu, Tingting; Chen, Huijuan
2013-03-01
As children mature, bike products for children in the market develop at the same time, and the conditions are frequently updated. Certain problems occur when using a bike, such as cycle overlapping, repeating function, and short life cycle, which go against the principles of energy conservation and the environmental protection intensive design concept. In this paper, a rational multi-function method of design through functional superposition, transformation, and technical implementation is proposed. An organic combination of frog-style scooter and children's tricycle is developed using the multi-function method. From the ergonomic perspective, the paper elaborates on the body size of children aged 5 to 12 and effectively extracts data for a multi-function children's bike, which can be used for gliding and riding. By inverting the body, parts can be interchanged between the handles and the pedals of the bike. Finally, the paper provides a detailed analysis of the components and structural design, body material, and processing technology of the bike. The study of Industrial Product Innovation Design provides an effective design method to solve the bicycle problems, extends the function problems, improves the product market situation, and enhances the energy saving feature while implementing intensive product development effectively at the same time.
King, Randy L; Liu, Yunbo; Maruvada, Subha; Herman, Bruce A; Wear, Keith A; Harris, Gerald R
2011-07-01
A tissue-mimicking material (TMM) for the acoustic and thermal characterization of high-intensity focused ultrasound (HIFU) devices has been developed. The material is a high-temperature hydrogel matrix (gellan gum) combined with different sizes of aluminum oxide particles and other chemicals. The ultrasonic properties (attenuation coefficient, speed of sound, acoustical impedance, and the thermal conductivity and diffusivity) were characterized as a function of temperature from 20 to 70°C. The backscatter coefficient and nonlinearity parameter B/A were measured at room temperature. Importantly, the attenuation coefficient has essentially linear frequency dependence, as is the case for most mammalian tissues at 37°C. The mean value is 0.64f(0.95) dB·cm(-1) at 20°C, based on measurements from 2 to 8 MHz. Most of the other relevant physical parameters are also close to the reported values, although backscatter signals are low compared with typical human soft tissues. Repeatable and consistent temperature elevations of 40°C were produced under 20-s HIFU exposures in the TMM. This TMM is appropriate for developing standardized dosimetry techniques, validating numerical models, and determining the safety and efficacy of HIFU devices.
Advanced high efficiency wraparound contact solar cell
NASA Technical Reports Server (NTRS)
Scott-Monck, J. A.; Uno, F. M.; Thornhill, J. W.
1977-01-01
A significant advancement in the development of thin high efficiency wraparound contact silicon solar cells has been made by coupling space and terrestrial processing procedures. Although this new method for fabricating cells has not been completely reduced to practice, some of the initial cells have delivered over 20 mW/sq cm when tested at 25 C under AMO intensity. This approach not only yields high efficiency devices, but shows promise of allowing complete freedom of choice in both the location and size of the wraparound contact pad area.
Advanced high efficiency wraparound contact solar cell
NASA Technical Reports Server (NTRS)
Scott-Monck, J. A.; Uno, F. M.; Thornhill, J. W.
1977-01-01
A significant advancement in the development of thin high efficiency wraparound contact silicon solar cells has been made by coupling space and terrestrial processing procedures. Although this new method for fabricating cells has not been completely reduced to practice, some of the initial cells have delivered over 20 mW/sq cm when tested at 25 C under AMO intensity. This approach not only yields high efficiency devices, but shows promise of allowing complete freedom of choice in both the location and size of the wraparound contact pad area
A Fatigue Life Prediction Method Based on Strain Intensity Factor
Zhang, Wei; Liu, Huili; Wang, Qiang; He, Jingjing
2017-01-01
In this paper, a strain-intensity-factor-based method is proposed to calculate the fatigue crack growth under the fully reversed loading condition. A theoretical analysis is conducted in detail to demonstrate that the strain intensity factor is likely to be a better driving parameter correlated with the fatigue crack growth rate than the stress intensity factor (SIF), especially for some metallic materials (such as 316 austenitic stainless steel) in the low cycle fatigue region with negative stress ratios R (typically R = −1). For fully reversed cyclic loading, the constitutive relation between stress and strain should follow the cyclic stress-strain curve rather than the monotonic one (it is a nonlinear function even within the elastic region). Based on that, a transformation algorithm between the SIF and the strain intensity factor is developed, and the fatigue crack growth rate testing data of 316 austenitic stainless steel and AZ31 magnesium alloy are employed to validate the proposed model. It is clearly observed that the scatter band width of crack growth rate vs. strain intensity factor is narrower than that vs. the SIF for different load ranges (which indicates that the strain intensity factor is a better parameter than the stress intensity factor under the fully reversed load condition). It is also shown that the crack growth rate is not uniquely determined by the SIF range even under the same R, but is also influenced by the maximum loading. Additionally, the fatigue life data (strain-life curve) of smooth cylindrical specimens are also used for further comparison, where a modified Paris equation and the equivalent initial flaw size (EIFS) are involved. The results of the proposed method have a better agreement with the experimental data compared to the stress intensity factor based method. Overall, the strain intensity factor method shows a fairly good ability in calculating the fatigue crack propagation, especially for the fully reversed cyclic loading condition. PMID:28773049
Theoretical Prediction of Si 2–Si 33 Absorption Spectra
DOE Office of Scientific and Technical Information (OSTI.GOV)
Zhao, Li -Zhen; Lu, Wen -Cai; Qin, Wei
Here, the optical absorption spectra of Si 2–Si 33 clusters were systematically studied by a time-dependent density functional theory approach. The calculations revealed that the absorption spectrum becomes significantly broad with increasing cluster size, stretching from ultraviolet to the infrared region. The absorption spectra are closely related to the structural motifs. With increasing cluster size, the absorption intensity of cage structures gradually increases, but the absorption curves of the prolate and the Y-shaped structures are very sensitive to cluster size. If the transition energy reaches ~12 eV, it is noted that all the clusters have remarkable absorption in deep ultravioletmore » region of 100–200 nm, and the maximum absorption intensity is ~100 times that in the visible region. Further, the optical responses to doping in the Si clusters were studied.« less
Theoretical Prediction of Si 2–Si 33 Absorption Spectra
Zhao, Li -Zhen; Lu, Wen -Cai; Qin, Wei; ...
2017-07-07
Here, the optical absorption spectra of Si 2–Si 33 clusters were systematically studied by a time-dependent density functional theory approach. The calculations revealed that the absorption spectrum becomes significantly broad with increasing cluster size, stretching from ultraviolet to the infrared region. The absorption spectra are closely related to the structural motifs. With increasing cluster size, the absorption intensity of cage structures gradually increases, but the absorption curves of the prolate and the Y-shaped structures are very sensitive to cluster size. If the transition energy reaches ~12 eV, it is noted that all the clusters have remarkable absorption in deep ultravioletmore » region of 100–200 nm, and the maximum absorption intensity is ~100 times that in the visible region. Further, the optical responses to doping in the Si clusters were studied.« less
NASA Astrophysics Data System (ADS)
Friese, Carmen A.; van der Does, Michèlle; Merkel, Ute; Iversen, Morten H.; Fischer, Gerhard; Stuut, Jan-Berend W.
2016-09-01
The particle sizes of Saharan dust in marine sediment core records have been used frequently as a proxy for trade-wind speed. However, there are still large uncertainties with respect to the seasonality of the particle sizes of deposited Saharan dust off northwestern Africa and the factors influencing this seasonality. We investigated a three-year time-series of grain-size data from two sediment-trap moorings off Cape Blanc, Mauritania and compared them to observed wind-speed and precipitation as well as satellite images. Our results indicate a clear seasonality in the grain-size distributions: during summer the modal grain sizes were generally larger and the sorting was generally less pronounced compared to the winter season. Gravitational settling was the major deposition process during winter. We conclude that the following two mechanisms control the modal grain size of the collected dust during summer: (1) wet deposition causes increased deposition fluxes resulting in coarser modal grain sizes and (2) the development of cold fronts favors the emission and transport of coarse particles off Cape Blanc. Individual dust-storm events throughout the year could be recognized in the traps as anomalously coarse-grained samples. During winter and spring, intense cyclonic dust-storm events in the dust-source region explained the enhanced emission and transport of a larger component of coarse particles off Cape Blanc. The outcome of our study provides important implications for climate modellers and paleo-climatologists.
Experimental investigations of pupil accommodation factors.
Lee, Eui Chul; Lee, Ji Woo; Park, Kang Ryoung
2011-08-17
PURPOSE. The contraction and dilation of the iris muscle that controls the amount of light entering the retina causes pupil accommodation. In this study, experiments were performed and two of the three factors that influence pupil accommodation were analyzed: lighting conditions and depth fixations. The psychological benefits were not examined, because they could not be quantified. METHODS. A head-wearable eyeglasses-based, eye-capturing device was designed to measure pupil size. It included a near-infrared (NIR) camera and an NIR light-emitting diode. Twenty-four subjects watched two-dimensional (2D) and three-dimensional (3D) stereoscopic videos of the same content, and the changes in pupil size were measured by using the eye-capturing device and image-processing methods: RESULTS. The pupil size changed with the intensity of the videos and the disparities between the left and right images of a 3D stereoscopic video. There was correlation between the pupil size and average intensity. The pupil diameter could be estimated as being contracted from approximately 5.96 to 4.25 mm as the intensity varied from 0 to 255. Further, from the changes in the depth fixation for the pupil accommodation, it was confirmed that the depth fixation also affected accommodation of pupil size. CONCLUSIONS. It was confirmed that the lighting condition was an even more significant factor in pupil accommodation than was depth fixation (significance ratio: approximately 3.2:1) when watching 3D stereoscopic video. Pupil accommodation was more affected by depth fixation in the real world than was the binocular convergence in the 3D stereoscopic display.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Bastami, Tahereh Rohani; Entezari, Mohammad H., E-mail: moh_entezari@yahoo.com
2013-09-01
Graphical abstract: - Highlights: • The sonochemical synthesis of magnetite nanoparticles was carried out in EG without any surfactant. • The nanoparticles with sizes ∼24 nm were composed of small building blocks with sizes ∼2 nm. • The hydrophilic magnetite nanoparticles were stable in ethanol even after 8 months. • Ultrasonic intensity showed a crucial role on the obtained high stable magnetite nanoparticles in ethanol. - Abstract: The sonochemical synthesis of magnetite nanoparticles was carried out at relatively low temperature (80 °C) in ethylene glycol (EG) as a polyol solvent. The particle size was determined by transmission electron microscopy (TEM).more » The magnetite nanoparticles with an average size of 24 nm were composed of small building blocks with an average size of 2–3 nm and the particles exhibited nearly spherical shape. The surface characterization was investigated by using Fourier transform infrared (FTIR) spectroscopy, X-ray photoelectron spectroscopy (XPS), and thermogravimetric analysis (TGA). The stability of magnetite nanoparticles was studied in ethanol as a polar solvent. The nanoparticles showed an enhanced stability in ethanol which is due to the hydrophilic surface of the particles. The colloidal stability of magnetite nanoparticles in ethanol was monitored by UV–visible spectrophotometer. According to the results, the nanoparticles synthesized in 30 min of sonication with intensity of 35 W/cm{sup 2} (50%) led to a maximum stability in ethanol as a polar solvent with respect to the other applied intensities. The obtained magnetite nanoparticles were stable for more than12 months.« less
Luminescent LuVO4:Ln3+ (Ln = Eu, Sm, Dy, Er) hollow porous spheres for encapsulation of biomolecules
NASA Astrophysics Data System (ADS)
Li, Dan; Liu, Chunlei; Jiang, Lianzhou
2015-10-01
In this study, LuVO4:Ln3+ (Ln = Eu, Sm, Dy, Er) hollow porous spheres, synthesized via self-sacrificing templated route, are developed for enzyme immobilization and protein adsorption. The four LuVO4 hollow spheres with diameter of 180 nm, 280 nm, 370 nm and 480 nm were obtained. The size of LuVO4 hollow sphere is dependent on Lu(OH)CO3 template. Upon excitation by UV light, hollow LuVO4:Ln3+ (Ln = Eu, Sm, Dy, Er) spheres exhibit red (Eu3+), orange (Sm3+), yellow-green (Dy3+), and green (Er3+) emissions. The good biocompatibility of sample is validated by MTT assay. Due to structure feature and size of obtained sample, the rapid encapsulation of biomolecules within samples has been achieved. Furthermore, the hollow spheres show different biomolecules adsorption capacities at different buffer solution pH values. The release behaviors of two kinds of biomolecules (lysozyme and bovine serum albumin) are also investigated. LuVO4 hollow spheres are suitable carriers for biomolecules. The emission intensity of Eu3+ in the LuVO4:Eu3+ varies with the released amount of LYZ. This enables the monitoring of release process by the change in the luminescence intensity.
NASA Astrophysics Data System (ADS)
Austin, N. J.; Evans, B.; Dresen, G. H.; Rybacki, E.
2009-12-01
Deformed rocks commonly consist of several mineral phases, each with dramatically different mechanical properties. In both naturally and experimentally deformed rocks, deformation mechanisms and, in turn, strength, are commonly investigated by analyzing microstructural elements such as crystallographic preferred orientation (CPO) and recrystallized grain size. Here, we investigated the effect of variations in the volume fraction and the geometry of rigid second phases on the strength and evolution of CPO and grain size of synthetic calcite rocks. Experiments using triaxial compression and torsional loading were conducted at 1023 K and equivalent strain rates between ~2e-6 and 1e-3 s-1. The second phases in these synthetic assemblages are rigid carbon spheres or splinters with known particle size distributions and geometries, which are chemically inert at our experimental conditions. Under hydrostatic conditions, the addition of as little as 1 vol.% carbon spheres poisons normal grain growth. Shape is also important: for an equivalent volume fraction and grain dimension, carbon splinters result in a finer calcite grain size than carbon spheres. In samples deformed at “high” strain rates, or which have “large” mean free spacing of the pinning phase, the final recrystallized grain size is well explained by competing grain growth and grain size reduction processes, where the grain-size reduction rate is determined by the rate that mechanical work is done during deformation. In these samples, the final grain size is finer than in samples heat-treated hydrostatically for equivalent durations. The addition of 1 vol.% spheres to calcite has little effect on either the strength or CPO development. Adding 10 vol.% splinters increases the strength at low strains and low strain rates, but has little effect on the strength at high strains and/or high strain rates, compared to pure samples. A CPO similar to that in pure samples is observed, although the intensity is reduced in samples containing 10 vol.% splinters. When 10 vol.% spheres are added to calcite, the strength of the aggregate is reduced, and a distinct and strong CPO develops. Viscoplastic self consistent calculations were used to model the evolution of CPO in these materials, and these suggest a variation in the activity of the various slip systems within pure samples and those containing 10 vol.% spheres. The applicability of these laboratory observations has been tested with field-based observations made in the Morcles Nappe (Swiss Helvetic Alps). In the Morcles Nappe, calcite grain size becomes progressively finer as the thrust contact is approached, and there is a concomitant increase in CPO intensity, with the strongest CPO’s in the finest-grained, quartz-rich limestones, nearest the thrust contact, which are interpreted to have been deformed to the highest strains. Thus, our laboratory results may be used to provide insight into the distribution of strain observed in natural shear zones.
Hegab, Ahmed E; Kameyama, Naofumi; Kuroda, Aoi; Kagawa, Shizuko; Yin, Yongjun; Ornitz, David; Betsuyaku, Tomoko
2016-05-20
Lung cancer is the most lethal cancer in the world. Intensive research is ongoing worldwide to identify new therapies for lung cancer. Several mouse models of lung cancer are being used to study the mechanism of cancer development and to experiment with various therapeutic strategies. However, the absence of a real-time technique to identify the development of tumor nodules in mice lungs and to monitor the changes in their size in response to various experimental and therapeutic interventions hampers the ability to obtain an accurate description of the course of the disease and its timely response to treatments. In this study, a method using a micro-computed tomography (CT) scanner for the detection of the development of lung tumors in a mouse model of lung adenocarcinoma is described. Next, we show that monthly follow-up with micro-CT can identify dynamic changes in the lung tumor, such as the appearance of additional nodules, increase in the size of previously detected nodules, and decrease in the size or complete resolution of nodules in response to treatment. Finally, the accuracy of this real-time assessment method was confirmed with end-point histological quantification. This technique paves the way for planning and conducting more complex experiments on lung cancer animal models, and it enables us to better understand the mechanisms of carcinogenesis and the effects of different treatment modalities while saving time and resources.
Dynamics of Cavitation Clouds within a High-Intensity Focused Ultrasonic Beam
2012-03-01
the cloud size. I. INTRODUCTION High-intensity focused ultrasound ( HIFU ), along with the associated cavitation, is used in a variety of fields. The...this experimental study, we generate a 500 kHz high-intensity focused ultrasonic ( HIFU ) beam, with pressure amplitude in the focal zone of up to 1.9 MPa... focused ultrasonic ( HIFU ) beam, with pressure amplitude in the focal zone of up to 1.9 MPa, in initially quiescent water. The resulting pressure field
Shen, Zhenyao; Liu, Jin; Aini, Guzhanuer; Gong, Yongwei
2016-02-01
The deposition of pollutants on impervious surfaces is a serious problem associated with rapid urbanization, which results in non-point-source pollution. Characterizing the build-up and wash-off processes of pollutants in urban catchments is essential for urban planners. In this paper, the spatial variation and particle-size distributions of five heavy metals and two nutrients in surface dust were analyzed, and the runoff water first-flush effect (FF30) and event-mean concentrations (EMCs) of 10 common constituents were characterized. The relationships between runoff variables and stormwater characteristics were examined from three typical urban impervious surfaces in Beijing, China. Dust on road surfaces with smaller grain sizes had higher pollutant concentrations, whereas concentrations of Mn, Zn, Fe, and TP in roof surface dust increased with grain size. Particles with grain sizes of 38-74 and 125-300 μm contributed most to the total pollutant load in roads, while particles with the smallest grain sizes (<38 μm) contributed most on roofs (23.46-41.71 %). Event-mean concentrations (EMCs) and FF30 values for most runoff pollutants tended to be higher on roofs than on roads. The maximum intensity (I max) and the antecedent dry days (ADD) were critical parameters for EMCs in roads, while ADD was the only dominant parameter for EMCs on our studied roof. The rainfall intensity (RI) and maximum intensity (I max) were found to be the parameters with the strongest correlation to the first-flush effect on both roads and roofs. Significant correlations of total suspended solids (TSS) concentration in runoff with grain-size fractions of surface dust indicated that coarser particles (74-300 μm) are most likely to contribute to the solid-phase pollutants, and finer particles (<38 μm) are likely the main source of dissolved pollutants.
Acoustically levitated dancing drops: Self-excited oscillation to chaotic shedding.
Lin, Po-Cheng; I, Lin
2016-02-01
We experimentally demonstrate self-excited oscillation and shedding of millimeter-sized water drops, acoustically levitated in a single-node standing waves cavity, by decreasing the steady acoustic wave intensity below a threshold. The perturbation of the acoustic field by drop motion is a possible source for providing an effective negative damping for sustaining the growing amplitude of the self-excited motion. Its further interplay with surface tension, drop inertia, gravity and acoustic intensities, select various self-excited modes for different size of drops and acoustic intensity. The large drop exhibits quasiperiodic motion from a vertical mode and a zonal mode with growing coupling, as oscillation amplitudes grow, until falling on the floor. For small drops, chaotic oscillations constituted by several broadened sectorial modes and corresponding zonal modes are self-excited. The growing oscillation amplitude leads to droplet shedding from the edges of highly stretched lobes, where surface tension no longer holds the rapid expanding flow.
Acoustically levitated dancing drops: Self-excited oscillation to chaotic shedding
NASA Astrophysics Data System (ADS)
Lin, Po-Cheng; I, Lin
2016-02-01
We experimentally demonstrate self-excited oscillation and shedding of millimeter-sized water drops, acoustically levitated in a single-node standing waves cavity, by decreasing the steady acoustic wave intensity below a threshold. The perturbation of the acoustic field by drop motion is a possible source for providing an effective negative damping for sustaining the growing amplitude of the self-excited motion. Its further interplay with surface tension, drop inertia, gravity and acoustic intensities, select various self-excited modes for different size of drops and acoustic intensity. The large drop exhibits quasiperiodic motion from a vertical mode and a zonal mode with growing coupling, as oscillation amplitudes grow, until falling on the floor. For small drops, chaotic oscillations constituted by several broadened sectorial modes and corresponding zonal modes are self-excited. The growing oscillation amplitude leads to droplet shedding from the edges of highly stretched lobes, where surface tension no longer holds the rapid expanding flow.
Method and apparatus for inspecting reflection masks for defects
Bokor, Jeffrey; Lin, Yun
2003-04-29
An at-wavelength system for extreme ultraviolet lithography mask blank defect detection is provided. When a focused beam of wavelength 13 nm is incident on a defective region of a mask blank, three possible phenomena can occur. The defect will induce an intensity reduction in the specularly reflected beam, scatter incoming photons into an off-specular direction, and change the amplitude and phase of the electric field at the surface which can be monitored through the change in the photoemission current. The magnitude of these changes will depend on the incident beam size, and the nature, extent and size of the defect. Inspection of the mask blank is performed by scanning the mask blank with 13 nm light focused to a spot a few .mu.m in diameter, while measuring the reflected beam intensity (bright field detection), the scattered beam intensity (dark-field detection) and/or the change in the photoemission current.
How to predict the spread and intensity of forest and range fires
Richard C. Rothermel
1983-01-01
This manual documents procedures for estimating the rate of forward spread, intensity, flame length, and size of fires burning in forests and rangelands. Contains instructions for obtaining fuel and weather data, calculating fire behavior, and interpreting the results for application to actual fire problems. This is a companion publication to "
ERIC Educational Resources Information Center
Bauman, Laurie J.; Karasz, Alison; Hamilton, Adaoha
2007-01-01
Although interventions based on cognitive theories can reduce rates of unsafe sexual behavior in adolescents, effect sizes remain small. This study was a qualitative investigation of inner-city adolescents' intentions to use condoms following participation in an intensive safer sex program. In-depth interviews with 26 adolescents were analyzed…
Laser Intensity Scaling Through Stimulated Scattering in Optical Fibers
2001-12-17
Stokes beams transmitted through a 300 m multimode fiber. ..................................127 Figure 58: Circles (squares) indicate the measured size...circles) and first order Stokes (squares) beams at the fiber facet. (b,c) Pump (left) and Stokes (right) intensity distributions for a 300 m and...75 m fiber respectively. .......................................................................................130 Figure 61: Double clad fiber
NASA Astrophysics Data System (ADS)
Krissinel, Boris
2018-03-01
The paper reports the results of calculations of the center-to-limb intensity of optically thin line emission in EUV and FUV wavelength ranges. The calculations employ a multicomponent model for the quiescent solar corona. The model includes a collection of loops of various sizes, spicules, and free (inter-loop) matter. Theoretical intensity values are found from probabilities of encountering parts of loops in the line of sight with respect to the probability of absence of other coronal components. The model uses 12 loops with sizes from 3200 to 210000 km with different values of rarefaction index and pressure at the loop base and apex. The temperature at loop apices is 1 400 000 K. The calculations utilize the CHIANTI database. The comparison between theoretical and observed emission intensity values for coronal and transition region lines obtained by the SUMER, CDS, and EIS telescopes shows quite satisfactory agreement between them, particularly for the solar disk center. For the data acquired above the limb, the enhanced discrepancies after the analysis refer to errors in EIS measurements.
X-ray tomography investigation of intensive sheared Al–SiC metal matrix composites
DOE Office of Scientific and Technical Information (OSTI.GOV)
De Giovanni, Mario; Warnett, Jason M.; Williams, Mark A.
2015-12-15
X-ray computed tomography (XCT) was used to characterise three dimensional internal structure of Al–SiC metal matrix composites. The alloy composite was prepared by casting method with the application of intensive shearing to uniformly disperse SiC particles in the matrix. Visualisation of SiC clusters as well as porosity distribution were evaluated and compared with non-shearing samples. Results showed that the average particle size as well as agglomerate size is smaller in sheared sample compared to conventional cast samples. Further, it was observed that the volume fraction of porosity was reduced by 50% compared to conventional casting, confirming that the intensive shearingmore » helps in deagglomeration of particle clusters and decrease in porosity of Al–SiC metal matrix composites. - Highlights: • XCT was used to visualise 3D internal structure of Al-SiC MMC. • Al-SiC MMC was prepared by casting with the application of intensive shearing. • SiC particles and porosity distribution were evaluated. • Results show shearing deagglomerates particle clusters and reduces porosity in MMC.« less
Implications of the focal beam profile in serial femtosecond crystallography
DOE Office of Scientific and Technical Information (OSTI.GOV)
Galli, Lorenzo; Chapman, Henry N.; Metcalf, Peter
The photon density profile of an X-ray free-electron laser (XFEL) beam at the focal position is a critical parameter for serial femtosecond crystallography (SFX), but is difficult to measure because of the destructive power of the beam. A novel high intensity radiation induced phasing method (HIRIP) has been proposed as a general experimental approach for protein structure determination, but has proved to be sensitive to variations of the X-ray intensity, with uniform incident fluence desired for best performance. Here we show that experimental SFX data collected at the nano-focus chamber of the Coherent X-ray Imaging end-station at the Linac Coherentmore » Light Source using crystals with a limited size distribution suggests an average profile of the X-ray beam that has a large variation of intensity. We propose a new method to improve the quality of high fluence data for HI-RIP, by identifying and removing diffraction patterns from crystals exposed to the low intensity region of the beam. The method requires crystals of average size comparable to the width of the focal spot.« less
NASA Astrophysics Data System (ADS)
Flynn, Ryan
2007-12-01
The distribution of biological characteristics such as clonogen density, proliferation, and hypoxia throughout tumors is generally non-uniform, therefore it follows that the optimal dose prescriptions should also be non-uniform and tumor-specific. Advances in intensity modulated x-ray therapy (IMXT) technology have made the delivery of custom-made non-uniform dose distributions possible in practice. Intensity modulated proton therapy (IMPT) has the potential to deliver non-uniform dose distributions as well, while significantly reducing normal tissue and organ at risk dose relative to IMXT. In this work, a specialized treatment planning system was developed for the purpose of optimizing and comparing biologically based IMXT and IMPT plans. The IMXT systems of step-and-shoot (IMXT-SAS) and helical tomotherapy (IMXT-HT) and the IMPT systems of intensity modulated spot scanning (IMPT-SS) and distal gradient tracking (IMPT-DGT), were simulated. A thorough phantom study was conducted in which several subvolumes, which were contained within a base tumor region, were boosted or avoided with IMXT and IMPT. Different boosting situations were simulated by varying the size, proximity, and the doses prescribed to the subvolumes, and the size of the phantom. IMXT and IMPT were also compared for a whole brain radiation therapy (WBRT) case, in which a brain metastasis was simultaneously boosted and the hippocampus was avoided. Finally, IMXT and IMPT dose distributions were compared for the case of non-uniform dose prescription in a head and neck cancer patient that was based on PET imaging with the Cu(II)-diacetyl-bis(N4-methylthiosemicarbazone (Cu-ATSM) hypoxia marker. The non-uniform dose distributions within the tumor region were comparable for IMXT and IMPT. IMPT, however, was capable of delivering the same non-uniform dose distributions within a tumor using a 180° arc as for a full 360° rotation, which resulted in the reduction of normal tissue integral dose by a factor of up to three relative to IMXT, and the complete sparing of organs at risk distal to the tumor region.
The Impacts of Aerosols on Hurricane Katrina under the Effect of Air-Sea Coupling
NASA Astrophysics Data System (ADS)
Lin, Y.; Hsieh, J. S.; Wang, Y.; Zhang, R.
2017-12-01
Aerosols can affect the development of tropical cyclones, which often involve intense interactions with the ocean. Therefore, the impacts of aerosols on the tropical cyclones are reckoned closely associated with the effect of ocean feedback, a priori, which has often been omitted by most of the previous modeling studies about the aerosol effects on tropical cyclones. We investigate the synergetic effects of aerosols and ocean feedback on the development of hurricane Katrina using a convection-resolving coupled regional model (WRF-ROMS). In comparison with observations, our coupled simulation under pristine aerosol condition well captures the pressure drop near the center of Katrina with maximum mean sea level pressure in good agreement with the observation albeit the simulated maximal wind speed is relatively weaker than the observation. Preliminary results suggest that the ocean feedback tends to work with (against) aerosols to suppress (enhance) the hurricane's center pressure drop/maximum wind intensity at the developing (decaying) stage, suggesting a positive (negative) feedback to the aerosols' suppression effect on hurricanes. Moreover, the size of the simulated hurricane considerably expands due to the elevated polluted aerosols while the expansion is weakened, along with the increased precipitation, by the effect of air-sea interactions during the developing stage, which demonstrates intricate nonlinear interactions between aerosols, the hurricane and the ocean.
Wang, Xiaoyi; Wei, Ke; Yang, Zhongqi; Jennings, David E; Duan, Jian J
2016-05-19
Wing phenotype polymorphism is commonly observed in insects, yet little is known about the influence of environmental cues on the development or expression of the alternative phenotypes. Here, we report how both biotic and abiotic factors affect the wing morph differentiation of a bethylid parasitoid Sclerodermus pupariae. The percentage of winged female parasitoid progeny increased exponentially with temperature between 20 °C to 30 °C. Low intensity light and short-day photoperiod conditions also significantly induced the development of winged morphs. Interestingly, wingless maternal parasitoids produced more winged progeny. Furthermore, the degree of wing dimorphism was significantly influenced by the interactions between light intensity and maternal wing morphs. The percentage of winged female progeny was not significantly influenced by foundress densities, but increased significantly with parasitoid brood sizes. However, the percentage of male progeny increased significantly with the densities of maternal parasitoids. Our findings highlight the phenotypic partitioning of wing morphology and development in the parasitoid S. pupariae under varied environmental cues, and reveal the most favourable conditions for the production of winged females in this bethylid wasp. It is thus possible to increase winged female parasitoid production for the purposes of biological control by manipulation of biotic and abiotic conditions.
Determination of Atmospheric Aerosol Characteristics from the Polarization of Scattered Radiation
NASA Technical Reports Server (NTRS)
Harris, F. S., Jr.; McCormick, M. P.
1973-01-01
Aerosols affect the polarization of radiation in scattering, hence measured polarization can be used to infer the nature of the particles. Size distribution, particle shape, real and absorption parts of the complex refractive index affect the scattering. From Lorenz-Mie calculations of the 4-Stokes parameters as a function of scattering angle for various wavelengths the following polarization parameters were plotted: total intensity, intensity of polarization in plane of observation, intensity perpendicular to the plane of observation, polarization ratio, polarization (using all 4-Stokes parameters), plane of the polarization ellipse and its ellipticity. A six-component log-Gaussian size distribution model was used to study the effects of the nature of the polarization due to variations in the size distribution and complex refractive index. Though a rigorous inversion from measurements of scattering to detailed specification of aerosol characteristics is not possible, considerable information about the nature of the aerosols can be obtained. Only single scattering from aerosols was used in this paper. Also, the background due to Rayleigh gas scattering, the reduction of effects as a result of multiple scattering and polarization effects of possible ground background (airborne platforms) were not included.
Effective plasmonic mode-size converter.
Park, Hae-Ryeong; Park, Jong-Moon; Kim, Min-su; Ju, Jung Jin; Son, Jung-Han; Lee, Myung-Hyun
2011-10-24
Plasmonic mode-size converters (PMSCs) for long-range surface plasmon polaritons (LR-SPPs) at the wavelength of 1.55 μm are presented. The PMSC is composed of an insulator-metal-insulator waveguide (IMI-W), a laterally tapered insulator-metal-insulator-metal-insulator waveguide (LT-IMIMI-W), and an IMIMI-W in series. The mode-intensity sizes of the LR-SPPs for the IMI-W and the IMIMI-W were not only calculated using a finite element method but were also experimentally measured. The propagation losses of the IMI-W and the IMIMI-W as well as the coupling losses between them were analyzed by the cut-back method to investigate the effect of LT-IMIMI-Ws. By using the PMSC with a ~27 ° angled LT-IMIMI-W, the coupling loss between a polarization-maintaining fiber and a 3 μm-wide IMIMI-W was reduced by ~3.4 dB. Moreover, the resulting mode-intensity in the output of the PMSC was squeezed to ~35% of the mode-intensity in the input IMI-W. The PMSC may be potentially useful for bridging micro- to nano-plasmonic integrated circuits. © 2011 Optical Society of America
Anisimov, V N; Khavinsov, V Kh; Alimova, I N; Provintsiali, M; Manchini, R; Francheski, K
2002-02-01
Female transgenic FVB mice carrying breast cancer gene HER-2/neu were monthly injected with Vilon or Epithalon (1 microgram subcutaneously for 5 consecutive days) starting from the 2nd month of life. Epithalon markedly inhibited neoplasm development: the maximum size of breast adenocarcinomas was 33% lower than in the control (p < 0.05). The intensity of HER-2/neu mRNA expression in breast tumors of Epithalon-treated mice was 3.7 times lower than in control animals. These results indicate that Epithalon inhibits breast tumor development in transgenic mice, which is probably related to suppression of HER-2/neu expression.
US nonfuel mineral exploration: Selected findings for 1995-2009 from the USGS
Wilburn, David R.; Bleiwas, Donald I.
2012-01-01
The U.S. Geological Survey (USGS) has been systematically monitoring global nonfuel mineral exploration activities to anticipate the location and quantity of future nonfuel minerals supply for about 100 commodities, with an emphasis on precious and base metals. Since 1995, the USGS has developed an annual list of 100 noteworthy prospects that were considered to have a high level of potential for near-term development based on such criteria as intensity of drilling, level of capital investment, and size of resource. This study reviews the status of the U.S. sites included on these lists as of July 2011 and addresses domestic prospects not included on the lists that have come into production since 1995.
Wave-optical assessment of alignment tolerances in nano-focusing with ellipsoidal mirror
DOE Office of Scientific and Technical Information (OSTI.GOV)
Yumoto, Hirokatsu, E-mail: yumoto@spring8.or.jp; Koyama, Takahisa; Matsuyama, Satoshi
2016-01-28
High-precision ellipsoidal mirrors, which can efficiently focus X-rays to the nanometer dimension with a mirror, have not been realized because of the difficulties in the fabrication process. The purpose of our study was to develop nano-focusing ellipsoidal mirrors in the hard X-ray region. We developed a wave-optical focusing simulator for investigating alignment tolerances in nano-focusing with a designed ellipsoidal mirror, which produce a diffraction-limited focus size of 30 × 35 nm{sup 2} in full width at half maximum at an X-ray energy of 7 keV. The simulator can calculate focusing intensity distributions around the focal point under conditions of misalignment. Themore » wave-optical simulator enabled the calculation of interference intensity distributions, which cannot be predicted by the conventional ray-trace method. The alignment conditions with a focal length error of ≲ ±10 µm, incident angle error of ≲ ±0.5 µrad, and in-plane rotation angle error of ≲ ±0.25 µrad must be satisfied for nano-focusing.« less
Ghost imaging based on Pearson correlation coefficients
NASA Astrophysics Data System (ADS)
Yu, Wen-Kai; Yao, Xu-Ri; Liu, Xue-Feng; Li, Long-Zhen; Zhai, Guang-Jie
2015-05-01
Correspondence imaging is a new modality of ghost imaging, which can retrieve a positive/negative image by simple conditional averaging of the reference frames that correspond to relatively large/small values of the total intensity measured at the bucket detector. Here we propose and experimentally demonstrate a more rigorous and general approach in which a ghost image is retrieved by calculating a Pearson correlation coefficient between the bucket detector intensity and the brightness at a given pixel of the reference frames, and at the next pixel, and so on. Furthermore, we theoretically provide a statistical interpretation of these two imaging phenomena, and explain how the error depends on the sample size and what kind of distribution the error obeys. According to our analysis, the image signal-to-noise ratio can be greatly improved and the sampling number reduced by means of our new method. Project supported by the National Key Scientific Instrument and Equipment Development Project of China (Grant No. 2013YQ030595) and the National High Technology Research and Development Program of China (Grant No. 2013AA122902).
DOE Office of Scientific and Technical Information (OSTI.GOV)
Chang, Won; Stein, Michael L.; Wang, Jiali
Climate models robustly imply that some significant change in precipitation patterns will occur. Models consistently project that the intensity of individual precipitation events increases by approximately 6-7%/K, following the increase in atmospheric water content, but that total precipitation increases by a lesser amount (2-3%/K in the global average). Some other aspect of precipitation events must then change to compensate for this difference. We develop here a new methodology for identifying individual rainstorms and studying their physical characteristics - including starting location, intensity, spatial extent, duration, and trajectory - that allows identifying that compensating mechanism. We apply this technique to precipitationmore » over the contiguous U.S. from both radar-based data products and high-resolution model runs simulating 100 years of business-as-usual warming. In model studies, we find that the dominant compensating mechanism is a reduction of storm size. In summer, rainstorms become more intense but smaller; in winter, rainstorm shrinkage still dominates, but storms also become less numerous and shorter duration. These results imply that flood impacts from climate change will be less severe than would be expected from changes in precipitation intensity alone. We show also that projected changes are smaller than model-observation biases, implying that the best means of incorporating them into impact assessments is via "data-driven simulations" that apply model-projected changes to observational data. We therefore develop a simulation algorithm that statistically describes model changes in precipitation characteristics and adjusts data accordingly, and show that, especially for summertime precipitation, it outperforms simulation approaches that do not include spatial information.« less
NASA Technical Reports Server (NTRS)
Arnold, S. M.; Binienda, W. K.; Tan, H. Q.; Xu, M. H.
1992-01-01
Analytical derivations of stress intensity factors (SIF's) of a multicracked plate can be complex and tedious. Recent advances, however, in intelligent application of symbolic computation can overcome these difficulties and provide the means to rigorously and efficiently analyze this class of problems. Here, the symbolic algorithm required to implement the methodology described in Part 1 is presented. The special problem-oriented symbolic functions to derive the fundamental kernels are described, and the associated automatically generated FORTRAN subroutines are given. As a result, a symbolic/FORTRAN package named SYMFRAC, capable of providing accurate SIF's at each crack tip, was developed and validated. Simple illustrative examples using SYMFRAC show the potential of the present approach for predicting the macrocrack propagation path due to existing microcracks in the vicinity of a macrocrack tip, when the influence of the microcrack's location, orientation, size, and interaction are taken into account.
RECENT PROGRESS OF CRACK BRIDGING MODELING OF DUCTILE-PHASE-TOUGHENED W-CU COMPOSITES
DOE Office of Scientific and Technical Information (OSTI.GOV)
Setyawan, Wahyu; Henager, Charles H.; Wagner, Karla B.
2015-04-16
A crack bridging model using calculated Cu stress-strain curves has been developed to study the toughening of W-Cu composites. A strengthening factor and necking parameters have been added to the model for the ductile-phase bridges to incorporate constraint effects at small bridge sizes. Parametric studies are performed to investigate the effect of these parameters. The calculated maximum applied stress intensity, aKmax, to induce a 1-mm stable crack is compared to the experimental stress intensity at peak load, Kpeak. Without bridge necking, increasing the strengthening factor improves the agreement between aKmax and Kpeak when plotted vs. logarithm of the displacement rate.more » Improvement can also be achieved by allowing necking with a larger failure strain. While the slope is better matched with this latter approach, the calculated value of aKmax is significantly larger than Kpeak.« less
A rapid method for counting nucleated erythrocytes on stained blood smears by digital image analysis
Gering, E.; Atkinson, C.T.
2004-01-01
Measures of parasitemia by intraerythrocytic hematozoan parasites are normally expressed as the number of infected erythrocytes per n erythrocytes and are notoriously tedious and time consuming to measure. We describe a protocol for generating rapid counts of nucleated erythrocytes from digital micrographs of thin blood smears that can be used to estimate intensity of hematozoan infections in nonmammalian vertebrate hosts. This method takes advantage of the bold contrast and relatively uniform size and morphology of erythrocyte nuclei on Giemsa-stained blood smears and uses ImageJ, a java-based image analysis program developed at the U.S. National Institutes of Health and available on the internet, to recognize and count these nuclei. This technique makes feasible rapid and accurate counts of total erythrocytes in large numbers of microscope fields, which can be used in the calculation of peripheral parasitemias in low-intensity infections.
Temperate and boreal forest mega-fires: characteristics and challenges
Stephens, Scott L.; Burrows, Neil; Buyantuyev, Alexander; Gray, Robert W.; Keane, Robert E.; Kubian, Rick; Liu, Shirong; Seijo, Francisco; Shu, Lifu; Tolhurst, Kevin G.; Van Wagtendonk, Jan W.
2014-01-01
Mega-fires are often defined according to their size and intensity but are more accurately described by their socioeconomic impacts. Three factors – climate change, fire exclusion, and antecedent disturbance, collectively referred to as the “mega-fire triangle” – likely contribute to today's mega-fires. Some characteristics of mega-fires may emulate historical fire regimes and can therefore sustain healthy fire-prone ecosystems, but other attributes decrease ecosystem resiliency. A good example of a program that seeks to mitigate mega-fires is located in Western Australia, where prescribed burning reduces wildfire intensity while conserving ecosystems. Crown-fire-adapted ecosystems are likely at higher risk of frequent mega-fires as a result of climate change, as compared with other ecosystems once subject to frequent less severe fires. Fire and forest managers should recognize that mega-fires will be a part of future wildland fire regimes and should develop strategies to reduce their undesired impacts.
Liquid Metal Engineering by Application of Intensive Melt Shearing
NASA Astrophysics Data System (ADS)
Patel, Jayesh; Zuo, Yubo; Fan, Zhongyun
In all casting processes, liquid metal treatment is an essential step in order to produce high quality cast products. A new liquid metal treatment technology has been developed which comprises of a rotor/stator set-up that delivers high shear rate to the liquid melt. It generates macro-flow in a volume of melt for distributive mixing and intensive shearing for dispersive mixing. The high shear device exhibits significantly enhanced kinetics for phase transformations, uniform dispersion, distribution and size reduction of solid particles and gas bubbles, improved homogenisation of chemical composition and temperature fields and also forced wetting of usually difficult-to-wet solid particles in the liquid metal. Hence, it can benefit various casting processes to produce high quality cast products with refined microstructure and enhanced mechanical properties. Here, we report an overview on the application of the new high shear technology to the processing of light metal alloys.
COMPARISON OF VOLUMETRIC REGISTRATION ALGORITHMS FOR TENSOR-BASED MORPHOMETRY
Villalon, Julio; Joshi, Anand A.; Toga, Arthur W.; Thompson, Paul M.
2015-01-01
Nonlinear registration of brain MRI scans is often used to quantify morphological differences associated with disease or genetic factors. Recently, surface-guided fully 3D volumetric registrations have been developed that combine intensity-guided volume registrations with cortical surface constraints. In this paper, we compare one such algorithm to two popular high-dimensional volumetric registration methods: large-deformation viscous fluid registration, formulated in a Riemannian framework, and the diffeomorphic “Demons” algorithm. We performed an objective morphometric comparison, by using a large MRI dataset from 340 young adult twin subjects to examine 3D patterns of correlations in anatomical volumes. Surface-constrained volume registration gave greater effect sizes for detecting morphometric associations near the cortex, while the other two approaches gave greater effects sizes subcortically. These findings suggest novel ways to combine the advantages of multiple methods in the future. PMID:26925198
East African weathering dynamics controlled by vegetation-climate feedbacks
Ivory, Sarah J.; McGlue, Michael M.; Ellis, Geoffrey S.; Boehlke, Adam; Lézine, Anne-Marie; Vincens, Annie; Cohen, Andrew S.
2017-01-01
Tropical weathering has important linkages to global biogeochemistry and landscape evolution in the East African rift. We disentangle the influences of climate and terrestrial vegetation on chemical weathering intensity and erosion at Lake Malawi using a long sediment record. Fossil pollen, microcharcoal, particle size, and mineralogy data affirm that the detrital clays accumulating in deep water within the lake are controlled by feedbacks between climate and hinterland forest composition. Particle-size patterns are also best explained by vegetation, through feedbacks with lake levels, wildfires, and erosion. We develop a new source-to-sink framework that links lacustrine sedimentation to hinterland vegetation in tropical rifts. Our analysis suggests that climate-vegetation interactions and their coupling to weathering/erosion could threaten future food security and has implications for accurately predicting petroleum play elements in continental rift basins.
Mapping of radiation anomalies using UAV mini-airborne gamma-ray spectrometry.
Šálek, Ondřej; Matolín, Milan; Gryc, Lubomír
2018-02-01
Localization of size-limited gamma-ray anomalies plays a fundamental role in uranium prospecting and environmental studies. Possibilities of a newly developed mini-airborne gamma-ray spectrometric equipment were tested on a uranium anomaly near the village of Třebsko, Czech Republic. The measurement equipment was based on a scintillation gamma-ray spectrometer specially developed for unmanned aerial vehicles (UAV) mounted on powerful hexacopter. The gamma-ray spectrometer has two 103 cm 3 BGO scintillation detectors of relatively high sensitivity. The tested anomaly, which is 80 m by 40 m in size, was investigated by ground gamma-ray spectrometric measurement in a detail rectangular measurement grid. Average uranium concentration is 25 mg/kg eU attaining 700 mg/kg eU locally. The mini-airborne measurement across the anomaly was carried out on three 100 m long parallel profiles at eight flight altitudes from 5 to 40 m above the ground. The resulting 1 s 1024 channel gamma-ray spectra, recorded in counts per second (cps), were processed to concentration units of K, U and Th, while total count (TC) was reported in cps. Increased gamma ray intensity of the anomaly was indicated by mini-airborne measurement at all profiles and altitudes, including the highest altitude of 40 m, at which the recorded intensity is close to the natural radiation background. The reported instrument is able to record data with comparable quality as standard airborne survey, due to relative sensitive detector, lower flight altitude and relatively low flight speed of 1 m/s. The presented experiment brings new experience with using unmanned semi-autonomous aerial vehicles and the latest mini-airborne radiometric instrument. The experiment has demonstrated the instrument's ability to localize size-limited uranium anomalies. Copyright © 2017 Elsevier Ltd. All rights reserved.
Preparations of PbSe quantum dots in silicate glasses by a melt-annealing technique
NASA Astrophysics Data System (ADS)
Ma, D. W.; Cheng, C.; Zhang, Y. N.; Xu, Z. S.
2014-11-01
Silicate glass containing PbSe quantum dots (QDs) has important prospective applications in near infra-red optoelectronic devices. In this study, single-stage and double-stage heat-treatment methods were used respectively to prepare PbSe QDs in silicate glasses. Investigation results show that the double-stage heat-treatment is a favorable method to synthesize PbSe QDs with strong photoluminescence (PL) intensity and narrow full weight at half maximum (FWHM) in PL peak. Therefore, the method to prepare PbSe QDs was emphasized on the double-stage heat-treatment. Transmission electron microscopy measurements show that the standard deviations of the average QD sizes from the samples heat-treated at the development temperature of 550 °C fluctuate slightly in the range of 0.6-0.8 nm, while this deviation increases up to 1.2 nm for the sample with the development temperature of 600 °C. In addition, the linear relationship between the QD size and holding time indicates that the crystallization behavior of PbSe QDs in silicate glasses is interface-controlled growth in early stage of crystallization. The growth rates of PbSe QDs are determined to be 0.24 nm/h at 550 °C and 0.72 nm/h at 600 °C. In short, the double-stage heat-treatment at 450 °C for 20 h followed by heat-treatment at 550 °C for 5 h is a preferred process for the crystallization of PbSe QDs in silicate glass. Through this treatment, PbSe QDs with a narrow size dispersion of 5.0 ± 0.6 nm can be obtained, the PL peak from this sample is highest in intensity and narrowest in FWHM among all samples, and the peak is centered on 1575 nm, very close to the most common wavelength of 1550 nm in fiber-optic communication systems.
van der Meeren, Terje; Rønnestad, Ivar; Mangor-Jensen, Anders; Galloway, Trina F.; Kjørsvik, Elin; Hamre, Kristin
2015-01-01
The current commercial production protocols for Atlantic cod depend on enriched rotifers and Artemia during first-feeding, but development and growth remain inferior to fish fed natural zooplankton. Two experiments were conducted in order to identify the underlying factors for this phenomenon. In the first experiment (Exp-1), groups of cod larvae were fed either (a) natural zooplankton, mainly copepods, increasing the size of prey as the larvae grew or (b) enriched rotifers followed by Artemia (the intensive group). In the second experiment (Exp-2), two groups of larvae were fed as in Exp-1, while a third group was fed copepod nauplii (approximately the size of rotifers) throughout the larval stage. In both experiments, growth was not significantly different between the groups during the first three weeks after hatching, but from the last part of the rotifer feeding period and onwards, the growth of the larvae fed copepods was higher than that of the intensive group. In Exp-2, the growth was similar between the two copepod groups during the expeimental period, indicating that nutrient composition, not prey size caused the better growth on copepods. Analyses of the prey showed that total fatty acid composition and the ratio of phospholipids to total lipids was slightly different in the prey organisms, and that protein, taurine, astaxanthin and zinc were lower on a dry weight basis in rotifers than in copepods. Other measured nutrients as DHA, all analysed vitamins, manganese, copper and selenium were similar or higher in the rotifers. When compared to the present knowledge on nutrient requirements, protein and taurine appeared to be the most likely limiting nutrients for growth in cod larvae fed rotifers and Artemia. Larvae fed rotifers/Artemia had a higher whole body lipid content than larvae fed copepods at the end of the experiment (stage 5) after the fish had been fed the same formulated diet for approximately 2 weeks. PMID:26038712
Fluorescence imaging of tryptophan and collagen cross-links to evaluate wound closure ex vivo
NASA Astrophysics Data System (ADS)
Wang, Ying; Ortega-Martinez, Antonio; Farinelli, Bill; Anderson, R. R.; Franco, Walfre
2016-02-01
Wound size is a key parameter in monitoring healing. Current methods to measure wound size are often subjective, time-consuming and marginally invasive. Recently, we developed a non-invasive, non-contact, fast and simple but robust fluorescence imaging (u-FEI) method to monitor the healing of skin wounds. This method exploits the fluorescence of native molecules to tissue as functional and structural markers. The objective of the present study is to demonstrate the feasibility of using variations in the fluorescence intensity of tryptophan and cross-links of collagen to evaluate proliferation of keratinocyte cells and quantitate size of wound during healing, respectively. Circular dermal wounds were created in ex vivo human skin and cultured in different media. Two serial fluorescence images of tryptophan and collagen cross-links were acquired every two days. Histology and immunohistology were used to validate correlation between fluorescence and epithelialization. Images of collagen cross-links show fluorescence of the exposed dermis and, hence, are a measure of wound area. Images of tryptophan show higher fluorescence intensity of proliferating keratinocytes forming new epithelium, as compared to surrounding keratinocytes not involved in epithelialization. These images are complementary since collagen cross-links report on structure while tryptophan reports on function. HE and immunohistology show that tryptophan fluorescence correlates with newly formed epidermis. We have established a fluorescence imaging method for studying epithelialization processes during wound healing in a skin organ culture model, our approach has the potential to provide a non-invasive, non-contact, quick, objective and direct method for quantitative measurements in wound healing in vivo.
A study of the depth and size of concave cube Au nanoparticles as highly sensitive SERS probes
NASA Astrophysics Data System (ADS)
Romo-Herrera, J. M.; González, A. L.; Guerrini, L.; Castiello, F. R.; Alonso-Nuñez, G.; Contreras, O. E.; Alvarez-Puebla, R. A.
2016-03-01
High and uniform near fields are localized at the eight similar sharp corners of cubic gold nanoparticles. Moreover, by introducing concavity in the particle lateral planes, such field intensities can be further increased and tuned in the near infrared region without altering the overall size of the nanoparticles. Herein, we perform a thorough investigation of the morphological, crystallographic and plasmonic properties of concave gold nanocubes (GNCs) in the sub-70 nm size range, for their potential application as highly efficient SERS substrates in size-limiting cases. Theoretical calculations indicate that the highest increment of the near-field is located at the eight sharp tips and, interestingly, a medium near-field increment is also activated over the volume next to the concave surface. Remarkably, the plasmonic response of the concave cubic morphology showed great sensitivity to the concavity degree. Experimental SERS analysis nicely matches the outcome of the theoretical model, confirming that medium-sized concave GNCs (35 nm side length) possess the highest SERS activity upon excitation with a 633 nm laser, whereas larger 61 nm side concave GNCs dominate the optical response at 785 nm. Due to their size-intensity trade off, we envision that such small concave gold nanocubes can provide a highly active and efficient SERS platform for size-limiting applications, especially when near infrared excitations are required.High and uniform near fields are localized at the eight similar sharp corners of cubic gold nanoparticles. Moreover, by introducing concavity in the particle lateral planes, such field intensities can be further increased and tuned in the near infrared region without altering the overall size of the nanoparticles. Herein, we perform a thorough investigation of the morphological, crystallographic and plasmonic properties of concave gold nanocubes (GNCs) in the sub-70 nm size range, for their potential application as highly efficient SERS substrates in size-limiting cases. Theoretical calculations indicate that the highest increment of the near-field is located at the eight sharp tips and, interestingly, a medium near-field increment is also activated over the volume next to the concave surface. Remarkably, the plasmonic response of the concave cubic morphology showed great sensitivity to the concavity degree. Experimental SERS analysis nicely matches the outcome of the theoretical model, confirming that medium-sized concave GNCs (35 nm side length) possess the highest SERS activity upon excitation with a 633 nm laser, whereas larger 61 nm side concave GNCs dominate the optical response at 785 nm. Due to their size-intensity trade off, we envision that such small concave gold nanocubes can provide a highly active and efficient SERS platform for size-limiting applications, especially when near infrared excitations are required. Electronic supplementary information (ESI) available: Nanoparticle size distribution analysis (Fig. SI-1); extended TEM analysis on nanocubes morphology (Fig. SI-2, SI-3 and SI-4); comparison of GNCs size and concavity degree (Fig. SI-4); optical response calculations using the curved edges model (Fig. SI-5); simulated optical absorption spectra as a function of the concavity depth (Fig. SI-6); background SERS spectrum (Fig. SI-8) and details on the calculation of the SERS enhancement factors. See DOI: 10.1039/c6nr01155a
NASA Astrophysics Data System (ADS)
Sobol, N. V.; Gabbasova, I. M.; Komissarov, M. A.
2017-09-01
The effect of rainfall intensity on the erosion of residual calcareous agrogray soils and clay-illuvial agrochernozems in the Southern Cis-Ural region on slopes of different inclination and vegetation type has been studied by simulating with a small-size sprinkler. It has been shown that soil loss linearly depends on rainfall intensity (2, 4, and 6 mm/min) and slope inclination (3° and 7°). When the rainfall intensity and duration, and the slope inclination increase, soil loss by erosion from agrogray soils increases higher than from agrochernozems. On the plowland with a slope of 3°, runoff begins 12, 10, and 5 min, on the average, after the beginning of rains at these intensities. When the slope increases to 7°, runoff begins earlier by 7, 6, and 4 min, respectively. After the beginning of runoff and with its increase by 1 mm, the soil loss from slopes of 3° and 7° reaches 4.2 and 25.7 t/ha on agrogray soils and 1.4 and 4.7 t/ha on agrochernozems, respectively. Fallow soils have higher erosion resistance, and the soil loss little depends on the slope gradient: it gradually increases to 0.3-1.0 t/ha per 1 mm of runoff with increasing rainfall intensity and duration. The content of physical clay in eroded material is higher than in the original soils. Fine fractions prevail in this material, which increases their humus content. The increase in rainfall intensity and duration to 4 and 6 mm/min results in the entrapment of coarse silt and sand by runoff.
NASA Astrophysics Data System (ADS)
Celli, Jonathan P.; Rizvi, Imran; Evans, Conor L.; Abu-Yousif, Adnan O.; Hasan, Tayyaba
2010-09-01
Three-dimensional tumor models have emerged as valuable in vitro research tools, though the power of such systems as quantitative reporters of tumor growth and treatment response has not been adequately explored. We introduce an approach combining a 3-D model of disseminated ovarian cancer with high-throughput processing of image data for quantification of growth characteristics and cytotoxic response. We developed custom MATLAB routines to analyze longitudinally acquired dark-field microscopy images containing thousands of 3-D nodules. These data reveal a reproducible bimodal log-normal size distribution. Growth behavior is driven by migration and assembly, causing an exponential decay in spatial density concomitant with increasing mean size. At day 10, cultures are treated with either carboplatin or photodynamic therapy (PDT). We quantify size-dependent cytotoxic response for each treatment on a nodule by nodule basis using automated segmentation combined with ratiometric batch-processing of calcein and ethidium bromide fluorescence intensity data (indicating live and dead cells, respectively). Both treatments reduce viability, though carboplatin leaves micronodules largely structurally intact with a size distribution similar to untreated cultures. In contrast, PDT treatment disrupts micronodular structure, causing punctate regions of toxicity, shifting the distribution toward smaller sizes, and potentially increasing vulnerability to subsequent chemotherapeutic treatment.
Current methods for the size determination of nanomaterials in aqueous suspension include dynamic or static light scattering and electron or atomic force microscopy techniques. Light scattering techniques are limited by poor resolution and the scattering intensity dependence on p...
The mixing of rain with near-surface water
Dennis F. Houk
1976-01-01
Rain experiments were run with various temperature differences between the warm rain and the cool receiving water. The rain intensities were uniform and the raindrop sizes were usually uniform (2.2 mm, 3.6 mm, and 5.5 mm diameter drops). Two drop size distributions were also used.
Hydrologic Controls on Shallow Landslide Location, Size, and Shape
NASA Astrophysics Data System (ADS)
Bellugi, D.; Milledge, D.; Perron, T.; McKean, J. A.; Dietrich, W.; Rulli, M.
2012-12-01
Shallow landslides, typically involving just the soil mantle, are principally controlled by topography, soil and root strengths, and soil thickness, and are typically triggered by storm-induced increases in pore water pressure. The response of a landscape to landslide-triggering storms will thus depend on factors such as rainfall totals, storm intensity and duration, and antecedent moisture conditions. The two dominant mechanisms that generate high pore water pressures at a point are topographically-steered lateral subsurface flow (over timescales of days to weeks), and rapid vertical infiltration (over timescales of minutes to hours). We aim to understand the impact of different storm characteristics and hydrologic regimes on shallow landslide location, size, and shape. We have developed a regional-scale model, which applies a low-parameter grid-based multi-dimensional slope stability model within a novel search algorithm, to generate discrete landslide predictions. This model shows that the spatial organization of parameters such as root strength and pore water pressure has a strong control on shallow landslide location, size, and shape. We apply this model to a field site near Coos Bay, OR, where a ten-year landslide inventory has been mapped onto high-resolution topographic data. Our model predicts landslide size generally increases with increasing rainfall intensity, except when root strength is extremely high and pore pressures are topographically steered. The distribution of topographic index values (the ratios of contributing area to slope) of predicted landslides is a clear signature of the pore water pressure generation mechanism: as laterally dominated flow increases, landslides develop in locations with lower slopes and higher contributing areas; in contrast, in the case of vertically-dominated pore pressure rise, landslides are consistently found in locations with higher slopes and lower contributing areas. While in both cases landslides are found in the hollows, where the soils are sufficiently deep to overcome the effects of root strength, in the laterally-dominated case they are predicted to occur further down the hollows (which matches field observations). The size distribution of landslides is better predicted in our model when vertical infiltration dominates, but the observed distribution of topographic index values follows that predicted when lateral flow dominates. This suggests that both mechanisms must be taken into account in order to capture both location and size of shallow landslides (consistent with field observations). These results suggest that this modeling approach could allow us to use observed landslide locations and geometries to infer the dominant hydrologic triggering mechanisms. Furthermore, as the spatial and temporal resolution of precipitation forecasting improves, this model will enable us to more accurately predict both location and size of shallow landslides.
Naimi, Ladan J.; Sokhansanj, Shahabaddine; Bi, Xiaotao; ...
2015-11-25
Size reduction is an essential but energy-intensive process for preparing biomass for conversion processes. Three well-known scaling equations (Bond, Kick, and Rittinger) are used to estimate energy input for grinding minerals and food particles. Previous studies have shown that the Rittinger equation has the best fit to predict energy input for grinding cellulosic biomass. In the Rittinger equation, Rittinger's constant (k R) is independent of the size of ground particles, yet we noted large variations in k R among similar particle size ranges. In this research, the dependence of k R on the physical structure and chemical composition of amore » number of woody materials was explored. Branches from two softwood species (Douglas fir and pine) and two hardwood species (aspen and poplar) were ground in a laboratory knife mill. The recorded data included power input, mass flow rate, and particle size before and after grinding. Nine material properties were determined: particle density, solid density (pycnometer and x-ray diffraction methods), microfibril angle, fiber coarseness, fiber length, and composition (lignin and cellulose glucan contents). The correlation matrix among the nine properties revealed high degrees of interdependence between properties. The k R value had the largest positive correlation (+0.60) with particle porosity across the species tested. As a result, particle density was strongly correlated with lignin content (0.85), microfibril angle (0.71), fiber length (0.87), and fiber coarseness (0.78). An empirical model relating k R to particle density was developed.« less
DOE Office of Scientific and Technical Information (OSTI.GOV)
Naimi, Ladan J.; Sokhansanj, Shahabaddine; Bi, Xiaotao
Size reduction is an essential but energy-intensive process for preparing biomass for conversion processes. Three well-known scaling equations (Bond, Kick, and Rittinger) are used to estimate energy input for grinding minerals and food particles. Previous studies have shown that the Rittinger equation has the best fit to predict energy input for grinding cellulosic biomass. In the Rittinger equation, Rittinger's constant (k R) is independent of the size of ground particles, yet we noted large variations in k R among similar particle size ranges. In this research, the dependence of k R on the physical structure and chemical composition of amore » number of woody materials was explored. Branches from two softwood species (Douglas fir and pine) and two hardwood species (aspen and poplar) were ground in a laboratory knife mill. The recorded data included power input, mass flow rate, and particle size before and after grinding. Nine material properties were determined: particle density, solid density (pycnometer and x-ray diffraction methods), microfibril angle, fiber coarseness, fiber length, and composition (lignin and cellulose glucan contents). The correlation matrix among the nine properties revealed high degrees of interdependence between properties. The k R value had the largest positive correlation (+0.60) with particle porosity across the species tested. As a result, particle density was strongly correlated with lignin content (0.85), microfibril angle (0.71), fiber length (0.87), and fiber coarseness (0.78). An empirical model relating k R to particle density was developed.« less
Earthquake Hazard and the Environmental Seismic Intensity (ESI) Scale
NASA Astrophysics Data System (ADS)
Serva, Leonello; Vittori, Eutizio; Comerci, Valerio; Esposito, Eliana; Guerrieri, Luca; Michetti, Alessandro Maria; Mohammadioun, Bagher; Mohammadioun, Georgianna C.; Porfido, Sabina; Tatevossian, Ruben E.
2016-05-01
The main objective of this paper was to introduce the Environmental Seismic Intensity scale (ESI), a new scale developed and tested by an interdisciplinary group of scientists (geologists, geophysicists and seismologists) in the frame of the International Union for Quaternary Research (INQUA) activities, to the widest community of earth scientists and engineers dealing with seismic hazard assessment. This scale defines earthquake intensity by taking into consideration the occurrence, size and areal distribution of earthquake environmental effects (EEE), including surface faulting, tectonic uplift and subsidence, landslides, rock falls, liquefaction, ground collapse and tsunami waves. Indeed, EEEs can significantly improve the evaluation of seismic intensity, which still remains a critical parameter for a realistic seismic hazard assessment, allowing to compare historical and modern earthquakes. Moreover, as shown by recent moderate to large earthquakes, geological effects often cause severe damage"; therefore, their consideration in the earthquake risk scenario is crucial for all stakeholders, especially urban planners, geotechnical and structural engineers, hazard analysts, civil protection agencies and insurance companies. The paper describes background and construction principles of the scale and presents some case studies in different continents and tectonic settings to illustrate its relevant benefits. ESI is normally used together with traditional intensity scales, which, unfortunately, tend to saturate in the highest degrees. In this case and in unpopulated areas, ESI offers a unique way for assessing a reliable earthquake intensity. Finally, yet importantly, the ESI scale also provides a very convenient guideline for the survey of EEEs in earthquake-stricken areas, ensuring they are catalogued in a complete and homogeneous manner.
Guiding of Plasmons and Phonons in Complex Three Dimensional Structures
2013-01-01
typical sample. We employed X - ray diffraction (XRD) to measure the average grain size across the entire depth of the sample over spot sizes Figure...propagation distance L as the 1/e decay length of the field intensity along x ...as well as the network layout with subwavelegth gap size and internode distance on the order of the effective wavelength, a small 2 x 2 resonant
NASA Astrophysics Data System (ADS)
Kuo, Peng-Hsuan; Zhang, Bo-Cong; Su, Chie-Shaan; Liu, Jun-Jen; Sheu, Ming-Thau
2017-08-01
In this study, cooling sonocrystallization was used to recrystallize an active pharmaceutical ingredient, sulfathiazole, using methanol as the solvent. The effects of three operating parameters-sonication intensity, sonication duration, and solution concentration-on the recrystallization were investigated by using a 2k factorial design. The solid-state properties of sulfathiazole, including the mean particle size, crystal habit, and polymorphic form, were analyzed. Analysis of variance showed that the effect of the sonication intensity, cross-interaction effect of sonication intensity/sonication duration, and cross-interaction effect of sonication intensity/solution concentration on the recrystallization were significant. The results obtained using the 2k factorial design indicated that a combination of high sonication intensity and long sonication duration is not favorable for sonocrystallization, especially at a high solution concentration. A comparison of the solid-state properties of the original and the recrystallized sulfathiazole revealed that the crystal habit of the recrystallized sulfathiazole was more regular and that its mean particle size could be reduced to approximately 10 μm. Furthermore, the analytical results obtained using the PXRD, DSC, and FTIR spectroscopy indicated that the polymorphic purity of sulfathiazole improved from the original Form III/IV mixture to Form III after sonocrystallization.
NASA Astrophysics Data System (ADS)
Xia, Yong; Yin, Jianping
2005-03-01
We propose a new scheme to generate a focusing hollow beam (FHB) by use of an azimuthally distributed 2π-phase plate and a convergent thin lens. From the Fresnel diffraction theory, we calculate the intensity distributions of the FHB in free propagation space and study the relationship between the waist w0 of the incident Gaussian beam (or the focal length f of the lens) and the dark spot size (or the beam radius) at the focal point and the relationship between the maximum radial intensity of the FHB and the dark spot size (or the beam radius) at the focal point, respectively. Our study shows that the FHB can be used to cool and trap neutral atoms by intensity-gradient-induced Sisyphus cooling due to an extremely high intensity gradient of the FHB itself near the focal point, or to guide and focus a cold molecular beam. We also calculate the optical potential of the blue-detuned FHB for 85Rb atoms and find that in the focal plane, the smaller the dark spot size of the FHB is, the higher the optical potential is, and the greater the corresponding optimal detuning δ is; these qualities are beneficial to an atomic lens not only because it is profitable to obtain an atomic lens with a higher resolution, but also because it is helpful to reduce the spontaneous photon-scattering effect of atoms in the FHB.
Flume and field-based calibration of surrogate sensors for monitoring bedload transport
NASA Astrophysics Data System (ADS)
Mao, L.; Carrillo, R.; Escauriaza, C.; Iroume, A.
2016-01-01
Bedload transport assessment is important for geomorphological, engineering, and ecological studies of gravel-bed rivers. Bedload can be monitored at experimental stations that require expensive maintenance or by using portable traps, which allows measuring instantaneous transport rates but at a single point and at high costs and operational risks. The need for continuously measuring bedload intensity and dynamics has therefore increased the use and enhancement of surrogate methods. This paper reports on a set of flume experiments in which a Japanese acoustic pipe and an impact plate have been tested using four well-sorted and three poorly sorted sediment mixtures. Additional data were collected in a glacierized high-gradient Andean stream (Estero Morales) using a portable Bunte-type bedload sampler. Results show that the data provided by the acoustic pipe (which is amplified on 6 channels having different gains) can be calibrated for the grain size and for the intensity of transported sediments coarser than 9 mm (R2 = 0.93 and 0.88, respectively). Even if the flume-based calibration is very robust, upscaling the calibration to field applications is more challenging, and the bedload intensity could be predicted better than the grain size of transported sediments (R2 = 0.61 and 0.43, respectively). The inexpensive impact plate equipped with accelerometer could be calibrated for bedload intensity quite well in the flume but only poorly in the field (R2 = 0.16) and could not provide information on the size of transported sediments.
Energetic proton generation from intense Coulomb explosion of large-size ethane clusters
DOE Office of Scientific and Technical Information (OSTI.GOV)
Li Song; Zhou Zili; Tian Ye
An experimental investigation is performed on the interaction of intense femtosecond laser pulses at the intensity of 6 Multiplication-Sign 10{sup 17} W/cm{sup 2} (55 fs, 160 mJ at 800 nm) with ethane cluster (C{sub 2}H{sub 6}){sub N} jets prepared under the backing pressure of 30 bars at room temperature (298 K). The experiment results indicate the generation of energetic protons, whose average and maximum kinetic energies are 12.2 and 138.1 keV, respectively, by Coulomb explosion of (C{sub 2}H{sub 6}){sub N} clusters. (C{sub 2}H{sub 6}){sub N} clusters of 5 nm in radius are generated in the experiment, which are 1.7 timesmore » larger than that of (CH{sub 4}){sub N} clusters prepared in the same conditions. Empirical estimation suggests that (C{sub 2}H{sub 6}){sub N} clusters with radius of about 9.6 nm can be prepared at 80-bars backing pressure at 308 K. While (C{sub 2}H{sub 6}){sub N} clusters of so large size are irradiated by sufficiently intense laser pulses, the average energy of protons will be increased up to 50 keV. It is inferred that such large-size deuterated ethane clusters (C{sub 2}D{sub 6}){sub N} will favor more efficient neutron generation due to the significant increase of the D-D nuclear reaction cross section in laser-driven cluster nuclear fusion.« less
Investigating the Relation between Sunspots and Umbral Dots
NASA Astrophysics Data System (ADS)
Yadav, Rahul; Louis, Rohan E.; Mathew, Shibu K.
2018-03-01
Umbral dots (UDs) are transient, bright features observed in the umbral region of a sunspot. We study the physical properties of UDs observed in sunspots of different sizes. The aim of our study is to relate the physical properties of UDs with the large-scale properties of sunspots. For this purpose, we analyze high-resolution G-band images of 42 sunspots observed by Hinode/SOT, located close to disk center. The images were corrected for instrumental stray light and restored with the modeled point-spread function. An automated multilevel tracking algorithm was employed to identify the UDs located in selected G-band images. Furthermore, we employed Solar Dynamics Observatory/HMI, limb-darkening-corrected, full-disk continuum images to estimate the sunspot phase and epoch for the selected sunspots. The number of UDs identified in different umbrae exhibits a linear relation to the umbral size. The observed filling factor ranges from 3% to 7% and increases with the mean umbral intensity. Moreover, the filling factor shows a decreasing trend with the umbral size. We also found that the observed mean and maximum intensities of UDs are correlated with the mean umbral intensity. However, we do not find any significant relationship between the mean (and maximum) intensity and effective diameter of UDs and the sunspot area, epoch, and decay rate. We suggest that this lack of relation could be due to either the distinct transition of spatial scales associated with overturning convection in the umbra or the shallow depth associated with UDs, or both.
Connor, Richard C
2007-04-29
Bottlenose dolphins in Shark Bay, Australia, live in a large, unbounded society with a fission-fusion grouping pattern. Potential cognitive demands include the need to develop social strategies involving the recognition of a large number of individuals and their relationships with others. Patterns of alliance affiliation among males may be more complex than are currently known for any non-human, with individuals participating in 2-3 levels of shifting alliances. Males mediate alliance relationships with gentle contact behaviours such as petting, but synchrony also plays an important role in affiliative interactions. In general, selection for social intelligence in the context of shifting alliances will depend on the extent to which there are strategic options and risk. Extreme brain size evolution may have occurred more than once in the toothed whales, reaching peaks in the dolphin family and the sperm whale. All three 'peaks' of large brain size evolution in mammals (odontocetes, humans and elephants) shared a common selective environment: extreme mutual dependence based on external threats from predators or conspecific groups. In this context, social competition, and consequently selection for greater cognitive abilities and large brain size, was intense.
Apparatus for measuring particle properties
Rader, Daniel J.; Castaneda, Jaime N.; Grasser, Thomas W.; Brockmann, John E.
1998-01-01
An apparatus for determining particle properties from detected light scattered by the particles. The apparatus uses a light beam with novel intensity characteristics to discriminate between particles that pass through the beam and those that pass through an edge of the beam. The apparatus can also discriminate between light scattered by one particle and light scattered by multiple particles. The particle's size can be determined from the intensity of the light scattered. The particle's velocity can be determined from the elapsed time between various intensities of the light scattered.
Assessing hail risk for a building portfolio by generating stochastic events
NASA Astrophysics Data System (ADS)
Nicolet, Pierrick; Choffet, Marc; Demierre, Jonathan; Imhof, Markus; Jaboyedoff, Michel; Nguyen, Liliane; Voumard, Jérémie
2015-04-01
Among the natural hazards affecting buildings, hail is one of the most costly and is nowadays a major concern for building insurance companies. In Switzerland, several costly events were reported these last years, among which the July 2011 event, which cost around 125 million EUR to the Aargauer public insurance company (North-western Switzerland). This study presents the new developments in a stochastic model which aims at evaluating the risk for a building portfolio. Thanks to insurance and meteorological radar data of the 2011 Aargauer event, vulnerability curves are proposed by comparing the damage rate to the radar intensity (i.e. the maximum hailstone size reached during the event, deduced from the radar signal). From these data, vulnerability is defined by a two-step process. The first step defines the probability for a building to be affected (i.e. to claim damages), while the second, if the building is affected, attributes a damage rate to the building from a probability distribution specific to the intensity class. To assess the risk, stochastic events are then generated by summing a set of Gaussian functions with 6 random parameters (X and Y location, maximum hailstone size, standard deviation, eccentricity and orientation). The location of these functions is constrained by a general event shape and by the position of the previously defined functions of the same event. For each generated event, the total cost is calculated in order to obtain a distribution of event costs. The general events parameters (shape, size, …) as well as the distribution of the Gaussian parameters are inferred from two radar intensity maps, namely the one of the aforementioned event, and a second from an event which occurred in 2009. After a large number of simulations, the hailstone size distribution obtained in different regions is compared to the distribution inferred from pre-existing hazard maps, built from a larger set of radar data. The simulation parameters are then adjusted by trial and error, in order to get the best reproduction of the expected distributions. The value of the mean annual risk obtained using the model is also compared to the mean annual risk calculated using directly the hazard maps. According to the first results, the return period of an event inducing a total damage cost equal or greater than 125 million EUR for the Aargauer insurance company would be of around 10 to 40 years.
Life Cycle of Midlatitude Deep Convective Systems in a Lagrangian Framework
NASA Technical Reports Server (NTRS)
Feng, Zhe; Dong, Xiquan; Xie, Baike; McFarlane, Sally A.; Kennedy, Aaron; Lin, Bing; Minnis, Patrick
2012-01-01
Deep Convective Systems (DCSs) consist of intense convective cores (CC), large stratiform rain (SR) regions, and extensive non-precipitating anvil clouds (AC). This study focuses on the evolution of these three components and the factors that affect convective AC production. An automated satellite tracking method is used in conjunction with a recently developed multi-sensor hybrid classification to analyze the evolution of DCS structure in a Lagrangian framework over the central United States. Composite analysis from 4221 tracked DCSs during two warm seasons (May-August, 2010-2011) shows that maximum system size correlates with lifetime, and longer-lived DCSs have more extensive SR and AC. Maximum SR and AC area lag behind peak convective intensity and the lag increases linearly from approximately 1-hour for short-lived systems to more than 3-hours for long-lived ones. The increased lag, which depends on the convective environment, suggests that changes in the overall diabatic heating structure associated with the transition from CC to SR and AC could prolong the system lifetime by sustaining stratiform cloud development. Longer-lasting systems are associated with up to 60% higher mid-tropospheric relative humidity and up to 40% stronger middle to upper tropospheric wind shear. Regression analysis shows that the areal coverage of thick AC is strongly correlated with the size of CC, updraft strength, and SR area. Ambient upper tropospheric wind speed and wind shear also play an important role for convective AC production where for systems with large AC (radius greater than 120-km) they are 24% and 20% higher, respectively, than those with small AC (radius=20 km).
DOE Office of Scientific and Technical Information (OSTI.GOV)
Ma, Xuedan; Diroll, Benjamin T.; Cho, Wooje
Quasi-two-dimensional nanoplatelets (NPLs) possess fundamentally different excitonic properties from zero-dimensional quantum dots. We study lateral size-dependent photon emission statistics and carrier dynamics of individual NPLs using second-order photon correlation (g( 2)(τ)) spectroscopy and photoluminescence (PL) intensity-dependent lifetime analysis. Room-temperature radiative lifetimes of NPLs can be derived from maximum PL intensity periods in PL time traces. It first decreases with NPL lateral size and then stays constant, deviating from the electric dipole approximation. Analysis of the PL time traces further reveals that the single exciton quantum yield in NPLs decreases with NPL lateral size and increases with protecting shell thickness, indicatingmore » the importance of surface passivation on NPL emission quality. Second-order photon correlation (g( 2)(τ)) studies of single NPLs show that the biexciton quantum yield is strongly dependent on the lateral size and single exciton quantum yield of the NPLs. In large NPLs with unity single exciton quantum yield, the corresponding biexciton quantum yield can reach unity. In conclusion, these findings reveal that by careful growth control and core–shell material engineering, NPLs can be of great potential for light amplification and integrated quantum photonic applications.« less
DOE Office of Scientific and Technical Information (OSTI.GOV)
Young, P.E.
We are compiling a list of anticipated target spot sizes that are specified by the NIF users groups. This data will be used to anticipate demands for phase plates. The spot size also has an impact on the laser operation. Presently the phase plates are designed to sit in the leo section of the FOA (before the conversion crystals). Intensity modulations produced by the phase plates are nonlinearly proportional to the laser spot size. For spot sizes above 3 mm diameter, the intensity modulations are large enough that the damage threshold for the remainder of the FOA is exceeded. Formore » experiments requiring spot diameters larger than 3 ram, it is suggested that the phase plates sit in the 3{omega} section of the FOA. For planning purposes, the cost of the 3{omega} phase plates is presently projected to be more than that of a le0 phase plate due to the use of inclusion-free fused silica as the substrate material, This report is a summary of a meeting that we had on February 16, 2000 in order to catalogue the possible range of requested NIF spot sizes. Copies of the viewgraphs which were presented are also included.« less
NASA Astrophysics Data System (ADS)
Lipinska-Kalita, Kristina E.; Krol, Denise M.; Hemley, Russell J.; Mariotto, Gino; Kalita, Patricia E.; Ohki, Yoshimichi
2005-09-01
The precipitation and growth of copper nanoparticles in an optically transparent aluminosilicate glass matrix was investigated. The size of particles in this heterophase glass-based composite was modified in a controlled manner by isothermal heat treatments. A multitechnique approach, consisting of Raman scattering spectroscopy, high-resolution transmission electron microscopy, x-ray diffraction technique, and optical absorption spectroscopy, has been used to study the nucleation and crystallization processes. Optical absorption spectroscopy revealed the presence of intense absorption bands attributed to oscillations of free electrons, known as the surface-plasmon resonance band of copper particles, and confirmed a gradual increase of the particles' mean size and density with annealing time. The Raman scattering on acoustical phonons from Cu quantum dots in the glass matrix measured for off-resonance conditions demonstrated the presence of intense, inhomogeneously broadened peaks that have been assigned to the confined acoustic eigenmodes of copper nanoparticles. The particle-size dependence of the acoustic peak energies and the relation between the size distribution and bandwidths of these peaks were derived. High-resolution transmission electron microscopy was used to monitor the nucleation of the nanoparticles and to estimate their mean size.
Ma, Xuedan; Diroll, Benjamin T.; Cho, Wooje; ...
2017-08-08
Quasi-two-dimensional nanoplatelets (NPLs) possess fundamentally different excitonic properties from zero-dimensional quantum dots. We study lateral size-dependent photon emission statistics and carrier dynamics of individual NPLs using second-order photon correlation (g( 2)(τ)) spectroscopy and photoluminescence (PL) intensity-dependent lifetime analysis. Room-temperature radiative lifetimes of NPLs can be derived from maximum PL intensity periods in PL time traces. It first decreases with NPL lateral size and then stays constant, deviating from the electric dipole approximation. Analysis of the PL time traces further reveals that the single exciton quantum yield in NPLs decreases with NPL lateral size and increases with protecting shell thickness, indicatingmore » the importance of surface passivation on NPL emission quality. Second-order photon correlation (g( 2)(τ)) studies of single NPLs show that the biexciton quantum yield is strongly dependent on the lateral size and single exciton quantum yield of the NPLs. In large NPLs with unity single exciton quantum yield, the corresponding biexciton quantum yield can reach unity. In conclusion, these findings reveal that by careful growth control and core–shell material engineering, NPLs can be of great potential for light amplification and integrated quantum photonic applications.« less
Influence of mixing and ultrasound frequency on antisolvent crystallisation of sodium chloride.
Lee, Judy; Ashokkumar, Muthupandian; Kentish, Sandra E
2014-01-01
Ultrasound is known to promote nucleation of crystals and produce a narrower size distribution in a controlled and reproducible manner for the crystallisation process. Although there are various theories that suggest cavitation bubbles are responsible for sonocrystallisation, most studies use power ultrasonic horns that generate both intense shear and cavitation and this can mask the role that cavitation bubbles play. High frequency ultrasound from a plate transducer can be used to examine the effect of cavitation bubbles without the intense shear effect. This study reports the crystal size and morphology with various mixing speeds and ultrasound frequencies. The results show high frequency ultrasound produced sodium chloride crystals of similar size distribution as an ultrasonic horn. In addition, ultrasound generated sodium chloride crystals having a more symmetrical cubic structure compared to crystals produced by a high shear mixer. Copyright © 2013 Elsevier B.V. All rights reserved.
Molecular-like hierarchical self-assembly of monolayers of mixtures of particles
Singh, P.; Hossain, M.; Gurupatham, S. K.; Shah, K.; Amah, E.; Ju, D.; Janjua, M.; Nudurupati, S.; Fischer, I.
2014-01-01
We present a technique that uses an externally applied electric field to self-assemble monolayers of mixtures of particles into molecular-like hierarchical arrangements on fluid-liquid interfaces. The arrangements consist of composite particles (analogous to molecules) which are arranged in a pattern. The structure of a composite particle depends on factors such as the relative sizes of the particles and their polarizabilities, and the electric field intensity. If the particles sizes differ by a factor of two or more, the composite particle has a larger particle at its core and several smaller particles form a ring around it. The number of particles in the ring and the spacing between the composite particles depend on their polarizabilities and the electric field intensity. Approximately same sized particles form chains (analogous to polymeric molecules) in which positively and negatively polarized particles alternate. PMID:25510331
GPU-based ultra-fast dose calculation using a finite size pencil beam model.
Gu, Xuejun; Choi, Dongju; Men, Chunhua; Pan, Hubert; Majumdar, Amitava; Jiang, Steve B
2009-10-21
Online adaptive radiation therapy (ART) is an attractive concept that promises the ability to deliver an optimal treatment in response to the inter-fraction variability in patient anatomy. However, it has yet to be realized due to technical limitations. Fast dose deposit coefficient calculation is a critical component of the online planning process that is required for plan optimization of intensity-modulated radiation therapy (IMRT). Computer graphics processing units (GPUs) are well suited to provide the requisite fast performance for the data-parallel nature of dose calculation. In this work, we develop a dose calculation engine based on a finite-size pencil beam (FSPB) algorithm and a GPU parallel computing framework. The developed framework can accommodate any FSPB model. We test our implementation in the case of a water phantom and the case of a prostate cancer patient with varying beamlet and voxel sizes. All testing scenarios achieved speedup ranging from 200 to 400 times when using a NVIDIA Tesla C1060 card in comparison with a 2.27 GHz Intel Xeon CPU. The computational time for calculating dose deposition coefficients for a nine-field prostate IMRT plan with this new framework is less than 1 s. This indicates that the GPU-based FSPB algorithm is well suited for online re-planning for adaptive radiotherapy.
Development of a numerical model to predict physiological strain of firefighter in fire hazard.
Su, Yun; Yang, Jie; Song, Guowen; Li, Rui; Xiang, Chunhui; Li, Jun
2018-02-26
This paper aims to develop a numerical model to predict heat stress of firefighter under low-level thermal radiation. The model integrated a modified multi-layer clothing model with a human thermoregulation model. We took the coupled radiative and conductive heat transfer in the clothing, the size-dependent heat transfer in the air gaps, and the controlling active and controlled passive thermal regulation in human body into consideration. The predicted core temperature and mean skin temperature from the model showed a good agreement with the experimental results. Parametric study was conducted and the result demonstrated that the radiative intensity had a significant influence on the physiological heat strain. The existence of air gap showed positive effect on the physiological heat strain when air gap size is small. However, when the size of air gap exceeds 6 mm, a different trend was observed due to the occurrence of natural convection. Additionally, the time length for the existence of the physiological heat strain was greater than the existence of the skin burn under various heat exposures. The findings obtained in this study provide a better understanding of the physiological strain of firefighter and shed light on textile material engineering for achieving higher protective performance.
Location of Biomarkers and Reagents within Agarose Beads of a Programmable Bio-nano-chip
Jokerst, Jesse V.; Chou, Jie; Camp, James P.; Wong, Jorge; Lennart, Alexis; Pollard, Amanda A.; Floriano, Pierre N.; Christodoulides, Nicolaos; Simmons, Glennon W.; Zhou, Yanjie; Ali, Mehnaaz F.
2012-01-01
The slow development of cost-effective medical microdevices with strong analytical performance characteristics is due to a lack of selective and efficient analyte capture and signaling. The recently developed programmable bio-nano-chip (PBNC) is a flexible detection device with analytical behavior rivaling established macroscopic methods. The PBNC system employs ≈300 μm-diameter bead sensors composed of agarose “nanonets” that populate a microelectromechanical support structure with integrated microfluidic elements. The beads are an efficient and selective protein-capture medium suitable for the analysis of complex fluid samples. Microscopy and computational studies probe the 3D interior of the beads. The relative contributions that the capture and detection of moieties, analyte size, and bead porosity make to signal distribution and intensity are reported. Agarose pore sizes ranging from 45 to 620 nm are examined and those near 140 nm provide optimal transport characteristics for rapid (<15 min) tests. The system exhibits efficient (99.5%) detection of bead-bound analyte along with low (≈2%) nonspecific immobilization of the detection probe for carcinoembryonic antigen assay. Furthermore, the role analyte dimensions play in signal distribution is explored, and enhanced methods for assay building that consider the unique features of biomarker size are offered. PMID:21290601
Male Weaponry in a Fighting Cricket
Judge, Kevin A.; Bonanno, Vanessa L.
2008-01-01
Sexually selected male weaponry is widespread in nature. Despite being model systems for the study of male aggression in Western science and for cricket fights in Chinese culture, field crickets (Orthoptera, Gryllidae, Gryllinae) are not known to possess sexually dimorphic weaponry. In a wild population of the fall field cricket, Gryllus pennsylvanicus, we report sexual dimorphism in head size as well as the size of mouthparts, both of which are used when aggressive contests between males escalate to physical combat. Male G. pennsylvanicus have larger heads, maxillae and mandibles than females when controlling for pronotum length. We conducted two experiments to test the hypothesis that relatively larger weaponry conveys an advantage to males in aggressive contests. Pairs of males were selected for differences in head size and consequently were different in the size of maxillae and mandibles. In the first experiment, males were closely matched for body size (pronotum length), and in the second, they were matched for body mass. Males with proportionately larger weaponry won more fights and increasing differences in weaponry size between males increased the fighting success of the male with the larger weaponry. This was particularly true when contests escalated to grappling, the most intense level of aggression. However, neither contest duration nor intensity was related to weaponry size as predicted by models of contest settlement. These results are the first evidence that the size of the head capsule and mouthparts are under positive selection via male-male competition in field crickets, and validate 800-year-old Chinese traditional knowledge. PMID:19107188
Silicon-Etalon Fiber-Optic Temperature Sensor
NASA Technical Reports Server (NTRS)
Beheim, Glenn; Fritsch, Klaus; Flatico, Joseph M.; Azar, Massood Tabib
1993-01-01
Developmental temperature sensor consists of silicon Fabry-Perot etalon attached to end of optical fiber. Features immunity to electrical interference, small size, light weight, safety, and chemical inertness. Output encoded in ration of intensities at two different wavelengths, rather than in overall intensity, with result that temperature readings not degraded much by changes in transmittance of fiber-optic link.
NASA Astrophysics Data System (ADS)
Lv, Yan; Li, Xiang; Xu, Ting Ting; Cheng, Tian Tao; Yang, Xin; Chen, Jian Min; Iinuma, Yoshiteru; Herrmann, Hartmut
2016-03-01
In order to better understand the particle size distribution of polycyclic aromatic hydrocarbons (PAHs) and their source contribution to human respiratory system, size-resolved PAHs have been studied in ambient aerosols at a megacity Shanghai site during a 1-year period (2012-2013). The results showed the PAHs had a bimodal distribution with one mode peak in the fine-particle size range (0.4-2.1 µm) and another mode peak in the coarse-particle size range (3.3-9.0 µm). Along with the increase in ring number of PAHs, the intensity of the fine-mode peak increased, while the coarse-mode peak decreased. Plotting of log(PAH / PM) against log(Dp) showed that all slope values were above -1, suggesting that multiple mechanisms (adsorption and absorption) controlled the particle size distribution of PAHs. The total deposition flux of PAHs in the respiratory tract was calculated as being 8.8 ± 2.0 ng h-1. The highest lifetime cancer risk (LCR) was estimated at 1.5 × 10-6, which exceeded the unit risk of 10-6. The LCR values presented here were mainly influenced by accumulation mode PAHs which came from biomass burning (24 %), coal combustion (25 %), and vehicular emission (27 %). The present study provides us with a mechanistic understanding of the particle size distribution of PAHs and their transport in the human respiratory system, which can help develop better source control strategies.
Controlling the size and optical properties of ZnO nanoparticles by capping with SiO{sub 2}
DOE Office of Scientific and Technical Information (OSTI.GOV)
Babu, K. Sowri, E-mail: sowribabuk@gmail.com; Reddy, A. Ramachandra; Reddy, K. Venugopal
Graphical abstract: - Highlights: • Small and uniform sized ZnO nanoparticles were obtained with SiO{sub 2} coating. • ZnO and ZnO–SiO{sub 2} nanocomposite exhibited excitation wavelength dependent PL. • Maximum UV emission intensity was obtained with 353 nm excitation wavelength. • Excitation processes in SiO{sub 2} were also contributed to the UV intensity. • It was found that oxygen vacancies and interstitials enhanced with SiO{sub 2} coating. - Abstract: The size and shape of the ZnO nanoparticles synthesized through sol–gel method were controlled by capping with SiO{sub 2}. X-ray diffraction (XRD) and field emission scanning electron microscope (FE-SEM) and Highmore » Resolution Transmission Electron Microscope (HR-TEM) results demonstrated that the particle growth of the ZnO nanoparticles has been restricted to 5 nm with SiO{sub 2} capping. As a result, the absorption spectra of ZnO nanoparticles capped with SiO{sub 2} got blue shifted (toward lower wavelength side) due to strong quantum confinement effects. BET (Brunauer–Emmet–Teller) surface area pore size analyzer results showed that surface area of samples increased monotonously with increase of SiO{sub 2} concentration. It was observed that the absorption spectra of ZnO capped with SiO{sub 2} broadened with increase of SiO{sub 2} concentration. Absorption and photoluminescence excitation results (PLE) confirmed that this broadening is due to the absorption of non-bridging oxygen hole centers (NBOHC) of SiO{sub 2}. These results also indicated that ZnO nanoparticles capped with SiO{sub 2} are insensitive to Raman scattering. Maximum UV emission intensity was achieved with 353 nm excitation wavelength compared to 320 nm in ZnO as well as in SiO{sub 2} capped ZnO nanoparticles. Furthermore, there is an enhancement in the intensities of emission peaks related to oxygen vacancies and interstitials with SiO{sub 2} capping. The enhancement in the UV intensity is attributed to the surface passivation of ZnO nanoparticles and excitation processes in SiO{sub 2}.« less
Ghost hunting—an assessment of ghost particle detection and removal methods for tomographic-PIV
NASA Astrophysics Data System (ADS)
Elsinga, G. E.; Tokgoz, S.
2014-08-01
This paper discusses and compares several methods, which aim to remove spurious peaks, i.e. ghost particles, from the volume intensity reconstruction in tomographic-PIV. The assessment is based on numerical simulations of time-resolved tomographic-PIV experiments in linear shear flows. Within the reconstructed volumes, intensity peaks are detected and tracked over time. These peaks are associated with particles (either ghosts or actual particles) and are characterized by their peak intensity, size and track length. Peak intensity and track length are found to be effective in discriminating between most ghosts and the actual particles, although not all ghosts can be detected using only a single threshold. The size of the reconstructed particles does not reveal an important difference between ghosts and actual particles. The joint distribution of peak intensity and track length however does, under certain conditions, allow a complete separation of ghosts and actual particles. The ghosts can have either a high intensity or a long track length, but not both combined, like all the actual particles. Removing the detected ghosts from the reconstructed volume and performing additional MART iterations can decrease the particle position error at low to moderate seeding densities, but increases the position error, velocity error and tracking errors at higher densities. The observed trends in the joint distribution of peak intensity and track length are confirmed by results from a real experiment in laminar Taylor-Couette flow. This diagnostic plot allows an estimate of the number of ghosts that are indistinguishable from the actual particles.
Yoneyama, Takeshi; Watanabe, Tetsuyo; Kagawa, Hiroyuki; Hayashi, Yutaka; Nakada, Mitsutoshi
2017-03-01
In photodynamic diagnosis using 5-aminolevulinic acid (5-ALA), discrimination between the tumor and normal tissue is very important for a precise resection. However, it is difficult to distinguish between infiltrating tumor and normal regions in the boundary area. In this study, fluorescent intensity and bright spot analyses using a confocal microscope is proposed for the precise discrimination between infiltrating tumor and normal regions. From the 5-ALA-resected brain tumor tissue, the red fluorescent and marginal regions were sliced for observation under a confocal microscope. Hematoxylin and eosin (H&E) staining were performed on serial slices of the same tissue. According to the pathological inspection of the H&E slides, the tumor and infiltrating and normal regions on confocal microscopy images were investigated. From the fluorescent intensity of the image pixels, a histogram of pixel number with the same fluorescent intensity was obtained. The fluorescent bright spot sizes and total number were compared between the marginal and normal regions. The fluorescence intensity distribution and average intensity in the tumor were different from those in the normal region. The probability of a difference from the dark enhanced the difference between the tumor and the normal region. The bright spot size and number in the infiltrating tumor were different from those in the normal region. Fluorescence intensity analysis is useful to distinguish a tumor region, and a bright spot analysis is useful to distinguish between infiltrating tumor and normal regions. These methods will be important for the precise resection or photodynamic therapy of brain tumors. Copyright © 2016 Elsevier B.V. All rights reserved.
Analysis of Polder Polarization Measurements During Astex and Eucrex Experiments
NASA Technical Reports Server (NTRS)
Chen, Hui; Han, Qingyuan; Chou, Joyce; Welch, Ronald M.
1997-01-01
Polarization is more sensitive than intensity to cloud microstructure such as the particle size and shape, and multiple scattering does not wash out features in polarization as effectively as it does in the intensity. Polarization measurements, particularly in the near IR, are potentially a valuable tool for cloud identification and for studies of the microphysics of clouds. The POLDER instrument is designed to provide wide field of view bidirectional images in polarized light. During the ASTEX-SOFIA campaign on June 12th, 1992, over the Atlantic Ocean (near the Azores Islands), images of homogeneous thick stratocumulus cloud fields were acquired. During the EUCREX'94 (April, 1994) campaign, the POLDER instrument was flying over the region of Brittany (France), taking observations of cirrus clouds. This study involves model studies and data analysis of POLDER observations. Both models and data analysis show that POLDER can be used to detect cloud thermodynamic phases. Model results show that polarized reflection in the Lamda =0.86 micron band is sensitive to cloud droplet sizes but not to cloud optical thickness. Comparison between model and data analysis reveals that cloud droplet sizes during ASTEX are about 5 microns, which agrees very well with the results of in situ measurements (4-5 microns). Knowing the retrieved cloud droplet sizes, the total reflected intensity of the POLDER measurements then can be used to retrieve cloud optical thickness. The close agreement between data analysis and model results during ASTEX also suggests the homogeneity of the cloud layer during that campaign.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Shu, Yinan; Levine, Benjamin G., E-mail: levine@chemistry.msu.edu; Hohenstein, Edward G.
2015-01-14
Multireference quantum chemical methods, such as the complete active space self-consistent field (CASSCF) method, have long been the state of the art for computing regions of potential energy surfaces (PESs) where complex, multiconfigurational wavefunctions are required, such as near conical intersections. Herein, we present a computationally efficient alternative to the widely used CASSCF method based on a complete active space configuration interaction (CASCI) expansion built from the state-averaged natural orbitals of configuration interaction singles calculations (CISNOs). This CISNO-CASCI approach is shown to predict vertical excitation energies of molecules with closed-shell ground states similar to those predicted by state averaged (SA)-CASSCFmore » in many cases and to provide an excellent reference for a perturbative treatment of dynamic electron correlation. Absolute energies computed at the CISNO-CASCI level are found to be variationally superior, on average, to other CASCI methods. Unlike SA-CASSCF, CISNO-CASCI provides vertical excitation energies which are both size intensive and size consistent, thus suggesting that CISNO-CASCI would be preferable to SA-CASSCF for the study of systems with multiple excitable centers. The fact that SA-CASSCF and some other CASCI methods do not provide a size intensive/consistent description of excited states is attributed to changes in the orbitals that occur upon introduction of non-interacting subsystems. Finally, CISNO-CASCI is found to provide a suitable description of the PES surrounding a biradicaloid conical intersection in ethylene.« less
Zhang, Xiao-Lei; Zhang, Jie; Fan, Tuo; Ren, Wen-Jie; Lai, Chun-Hong
2014-09-01
In order to make surface-enhanced Raman scattering (SERS) substrates contained more "hot spots" in a three-dimensional (3D) focal volume, and can be adsorbed more probe molecules and metal nanoparticles, to obtain stronger Raman spectral signal, a new structure based on vertically aligned carbon nanotubes (CNTs) coated by Ag nanoparticles for surface Raman enhancement is presented. The vertically aligned CNTs are synthesized by chemical vapor deposition (CVD). A silver film is first deposited on the vertically aligned CNTs by magnetron sputtering. The samples are then annealed at different temperature to cause the different size silver nanoparticles to coat on the surface and sidewalls of vertically aligned CNTs. The result of scanning electron microscopy(SEM) shows that Ag nanoparticles are attached onto the sidewalls and tips of the vertically aligned CNTs, as the annealing temperature is different , pitch size, morphology and space between the silver nanoparticles is vary. Rhodamine 6G is served as the probe analyte. Raman spectrum measurement indicates that: the higher the concentration of R6G, the stronger the Raman intensity, but R6G concentration increase with the enhanced Raman intensity varies nonlinearly; when annealing temperature is 450 °C, the average size of silver nanoparticles is about 100 to 120 nm, while annealing temperature is 400 °C, the average size is about 70 nm, and the Raman intensity of 450 °C is superior to the annealing temperature that of 400 °C and 350 °C.
Simulating Bubble Plumes from Breaking Waves with a Forced-Air Venturi
NASA Astrophysics Data System (ADS)
Long, M. S.; Keene, W. C.; Maben, J. R.; Chang, R. Y. W.; Duplessis, P.; Kieber, D. J.; Beaupre, S. R.; Frossard, A. A.; Kinsey, J. D.; Zhu, Y.; Lu, X.; Bisgrove, J.
2017-12-01
It has been hypothesized that the size distribution of bubbles in subsurface seawater is a major factor that modulates the corresponding size distribution of primary marine aerosol (PMA) generated when those bubbles burst at the air-water interface. A primary physical control of the bubble size distribution produced by wave breaking is the associated turbulence that disintegrates larger bubbles into smaller ones. This leads to two characteristic features of bubble size distributions: (1) the Hinze scale which reflects a bubble size above which disintegration is possible based on turbulence intensity and (2) the slopes of log-linear regressions of the size distribution on either side of the Hinze scale that indicate the state of plume evolution or age. A Venturi with tunable seawater and forced air flow rates was designed and deployed in an artificial PMA generator to produce bubble plumes representative of breaking waves. This approach provides direct control of turbulence intensity and, thus, the resulting bubble size distribution characterizable by observations of the Hinze scale and the simulated plume age over a range of known air detrainment rates. Evaluation of performance in different seawater types over the western North Atlantic demonstrated that the Venturi produced bubble plumes with parameter values that bracket the range of those observed in laboratory and field experiments. Specifically, the seawater flow rate modulated the value of the Hinze scale while the forced-air flow rate modulated the plume age parameters. Results indicate that the size distribution of sub-surface bubbles within the generator did not significantly modulate the corresponding number size distribution of PMA produced via bubble bursting.
Spatial-temporal characteristics of lightning flash size in a supercell storm
NASA Astrophysics Data System (ADS)
Zhang, Zhixiao; Zheng, Dong; Zhang, Yijun; Lu, Gaopeng
2017-11-01
The flash sizes of a supercell storm, in New Mexico on October 5, 2004, are studied using the observations from the New Mexico Lightning Mapping Array and the Albuquerque, New Mexico, Doppler radar (KABX). First, during the temporal evolution of the supercell, the mean flash size is anti-correlated with the flash rate, following a unary power function, with a correlation coefficient of - 0.87. In addition, the mean flash size is linearly correlated with the area of reflectivity > 30 dBZ at 5 km normalized by the flash rate, with a correlation coefficient of 0.88. Second, in the horizontal, flash size increases along the direction from the region near the convection zone to the adjacent forward anvil. The region of minimum flash size usually corresponds to the region of maximum flash initiation and extent density. The horizontal correspondence between the mean flash size and the flash extent density can also be fitted by a unary power function, and the correlation coefficient is > 0.5 in 50% of the radar volume scans. Furthermore, the quality of fit is positively correlated to the convective intensity. Third, in the vertical direction, the height of the maximum flash initiation density is close to the height of maximum flash extent density, but corresponds to the height where the mean flash size is relatively small. In the discussion, the distribution of the small and dense charge regions when and where convection is vigorous in the storm, is deduced to be responsible for the relationship that flash size is temporally and spatially anti-correlated with flash rate and density, and the convective intensity.
NASA Astrophysics Data System (ADS)
Huh, Jangyong; Ji, Yunseo; Lee, Rena
2018-05-01
An X-ray control algorithm to modulate the X-ray intensity distribution over the FOV (field of view) has been developed by using numerical analysis and MCNP5, a particle transport simulation code on the basis of the Monte Carlo method. X-rays, which are widely used in medical diagnostic imaging, should be controlled in order to maximize the performance of the X-ray imaging system. However, transporting X-rays, like a liquid or a gas is conveyed through a physical form such as pipes, is not possible. In the present study, an X-ray control algorithm and technique to uniformize the Xray intensity projected on the image sensor were developed using a flattening filter and a collimator in order to alleviate the anisotropy of the distribution of X-rays due to intrinsic features of the X-ray generator. The proposed method, which is combined with MCNP5 modeling and numerical analysis, aimed to optimize a flattening filter and a collimator for a uniform distribution of X-rays. Their size and shape were estimated from the method. The simulation and the experimental results both showed that the method yielded an intensity distribution over an X-ray field of 6×4 cm2 at SID (source to image-receptor distance) of 5 cm with a uniformity of more than 90% when the flattening filter and the collimator were mounted on the system. The proposed algorithm and technique are not only confined to flattening filter development but can also be applied for other X-ray related research and development efforts.
Köhrmann, K U; Michel, M S; Steidler, A; Marlinghaus, E H; Kraut, O; Alken, P
2002-01-01
Therapeutic application of contactless thermoablation by high-intensity focused ultrasound (HIFU) demands precise physical definition of focal size and determination of control parameters. Our objective was to define the focal expansion of a new ultrasound generator and to evaluate the extent of tissue ablation under variable generator parameters in an ex vivo model. Axial and transversal distribution of ultrasound intensity in the area of the focal point was calculated by needle hydrophone. The extent of tissue necrosis after focused ultrasound was assessed in an ex vivo porcine kidney model applying generator power up to 400 Watt and pulse duration up to 8 s. The measurement of field distribution revealed a physical focal size of 32 x 4 mm. Sharp demarcation between coagulation necrosis and intact tissue was observed in our tissue model. Lesion size was kept under control by variation of both generator power and impulse duration. At a constant impulse duration of 2 s, generator power of 100 W remained below the threshold doses for induction of a reproducible lesion. An increase in power up to 200 W and 400 W, respectively, induced lesions with diameters up to 11.2 x 3 mm. Constant total energy (generator power x impulse duration) led to a larger lesion size under higher generator power. It is possible to induce sharply demarcated, reproducible thermonecrosis, which can be regulated by generator power and impulse duration, by means of a cylindrical piezo element with a paraboloid reflector at a focal distance of 10 cm. The variation of generator power was an especially suitable control parameter for the inducement of a defined lesion size.
Spatially explicit dynamic N-mixture models
Zhao, Qing; Royle, Andy; Boomer, G. Scott
2017-01-01
Knowledge of demographic parameters such as survival, reproduction, emigration, and immigration is essential to understand metapopulation dynamics. Traditionally the estimation of these demographic parameters requires intensive data from marked animals. The development of dynamic N-mixture models makes it possible to estimate demographic parameters from count data of unmarked animals, but the original dynamic N-mixture model does not distinguish emigration and immigration from survival and reproduction, limiting its ability to explain important metapopulation processes such as movement among local populations. In this study we developed a spatially explicit dynamic N-mixture model that estimates survival, reproduction, emigration, local population size, and detection probability from count data under the assumption that movement only occurs among adjacent habitat patches. Simulation studies showed that the inference of our model depends on detection probability, local population size, and the implementation of robust sampling design. Our model provides reliable estimates of survival, reproduction, and emigration when detection probability is high, regardless of local population size or the type of sampling design. When detection probability is low, however, our model only provides reliable estimates of survival, reproduction, and emigration when local population size is moderate to high and robust sampling design is used. A sensitivity analysis showed that our model is robust against the violation of the assumption that movement only occurs among adjacent habitat patches, suggesting wide applications of this model. Our model can be used to improve our understanding of metapopulation dynamics based on count data that are relatively easy to collect in many systems.
20. VIEW OF THE INTERIOR OF THE ADVANCED SIZE REDUCTION ...
20. VIEW OF THE INTERIOR OF THE ADVANCED SIZE REDUCTION FACILITY USED TO CUT PLUTONIUM CONTAMINATED GLOVE BOXES AND MISCELLANEOUS LARGE EQUIPMENT DOWN TO AN EASILY PACKAGED SIZE FOR DISPOSAL. ROUTINE OPERATIONS WERE PERFORMED REMOTELY, USING HOISTS, MANIPULATOR ARMS, AND GLOVE PORTS TO REDUCE BOTH INTENSITY AND TIME OF RADIATION EXPOSURE TO THE OPERATOR. (11/6/86) - Rocky Flats Plant, Plutonium Fabrication, Central section of Plant, Golden, Jefferson County, CO
Student Ratings of Instruction: Examining the Role of Academic Field, Course Level, and Class Size
ERIC Educational Resources Information Center
Laughlin, Anne M.
2014-01-01
This dissertation investigated the relationship between course characteristics and student ratings of instruction at a large research intensive university. Specifically, it examined the extent to which academic field, course level, and class size were associated with variation in mean class ratings. Past research consistently identifies…
Spatiotemporal variability of wildland fuels in US Northern Rocky Mountain forests
Robert E. Keane
2016-01-01
Fire regimes are ultimately controlled by wildland fuel dynamics over space and time; spatial distributions of fuel influence the size, spread, and intensity of individual fires, while the temporal distribution of fuel deposition influences fire's frequency and controls fire size. These "shifting fuel mosaics" are both a cause and a consequence...
NASA Astrophysics Data System (ADS)
Smith, S. L.; Vallina, S. M.; Merico, A.
2016-02-01
We examine Biodiversity and Ecosystem Function (BEF) in a model phytoplankton community, using two recently developed mechanisms for sustaining diversity. The Trait Diffusion (TD) formulation represents the maintenance of diversity via endogenous mechanisms, such as inter-generational trait plasticity and rapid evolution. The 'Kill-the-Winner' (KTW) formulation for grazing sustains prey biodiversity via the exogenous mechanism of active prey switching. We implement both TD and KTW in a continuous trait-distribution model using simplified size-scalings to define a gleaner-opportunist trade-off for a phytoplankton community. By simulating semi-continuous culture experiments with periodic external dilutions, we test the dynamic response of the phytoplankton community to different scenarios of pulsed nutrient supply. We quantify the short-term Adaptive Capacity (AC) of the community by the specific growth rate averaged over the first 3 days of perturbations, and the Long-term Productivity (LP) by its average over the entire 120 day period of perturbations. When either the frequency or intensity of pulses is low, both AC and LP tend to decrease with diversity (and vice versa). Trait diversity has more impact on AC, particularly for pulses of high frequency or intensity, for which it tends to increase gradually at first, then steeply, and then to saturate with increasing diversity. For pulses of moderate intensity and frequency, increasing trait diversity from low to moderate levels leads to a trade-off between enhancing AC while slightly decreasing LP. Ultimately, we find that sustaining diversity increases the speed at which the phytoplankton community changes its composition in terms of size and hence nutrient acquisition traits, which may have implications for the transfer of productivity through the foodweb.
Automatic detection of cardiovascular risk in CT attenuation correction maps in Rb-82 PET/CTs
NASA Astrophysics Data System (ADS)
Išgum, Ivana; de Vos, Bob D.; Wolterink, Jelmer M.; Dey, Damini; Berman, Daniel S.; Rubeaux, Mathieu; Leiner, Tim; Slomka, Piotr J.
2016-03-01
CT attenuation correction (CTAC) images acquired with PET/CT visualize coronary artery calcium (CAC) and enable CAC quantification. CAC scores acquired with CTAC have been suggested as a marker of cardiovascular disease (CVD). In this work, an algorithm previously developed for automatic CAC scoring in dedicated cardiac CT was applied to automatic CAC detection in CTAC. The study included 134 consecutive patients undergoing 82-Rb PET/CT. Low-dose rest CTAC scans were acquired (100 kV, 11 mAs, 1.4mm×1.4mm×3mm voxel size). An experienced observer defined the reference standard with the clinically used intensity level threshold for calcium identification (130 HU). Five scans were removed from analysis due to artifacts. The algorithm extracted potential CAC by intensity-based thresholding and 3D connected component labeling. Each candidate was described by location, size, shape and intensity features. An ensemble of extremely randomized decision trees was used to identify CAC. The data set was randomly divided into training and test sets. Automatically identified CAC was quantified using volume and Agatston scores. In 33 test scans, the system detected on average 469mm3/730mm3 (64%) of CAC with 36mm3 false positive volume per scan. The intraclass correlation coefficient for volume scores was 0.84. Each patient was assigned to one of four CVD risk categories based on the Agatston score (0-10, 11-100, 101-400, <400). The correct CVD category was assigned to 85% of patients (Cohen's linearly weighted κ0.82). Automatic detection of CVD risk based on CAC scoring in rest CTAC images is feasible. This may enable large scale studies evaluating clinical value of CAC scoring in CTAC data.
Local extension of HMGB1 in atherosclerotic lesions of human main cerebral and carotid arteries.
Umahara, T; Uchihara, T; Koyama, S; Hashimoto, T; Akimoto, J; Haraoka, J; Iwamoto, T
2014-02-01
High mobility group box 1 protein (HMGB1) is a non-histone chromosomal protein which is highly conserved, ubiquitous, and widely distributed. HMGB1 has multiple functions in the nucleus, including the maintenance of nucleosome structure, the regulation of gene transcription, and involvement in DNA recombination. HMBG1 is currently recognized to have a wide range of potential functions and pathological relevance. HMGB1 is released into the extracellular space from necrotic cells and from activated macrophages. HMGB1 binds to the receptor for advanced glycation end products, resulting in the induction of inflammatory cytokines, and to endothelial cell thrombomodulin. HMGB1 neutralization may also reduce the development of atherosclerosis and ameliorate brain infarction. We investigated the immunolocalization of HMGB1 in atherosclerotic lesions of human cerebral and carotid arteries using a specific antibody, and confirmed the detailed expression and cell type localization using double immunofluorolabeling. In the main cerebral arteries, this anti-HMGB1 antibody intensely immunolabeled both normal morphological vascular smooth muscle cells (VSMCs) within the tunica media and infiltrating VSMCs within the intima of thickened fibrous cap plaques. Endothelial cells were also positive for HMGB1. In carotid plaques, HMGB1-like immunoreactivity (IR) was intense in macrophages, although this IR decreased with increasing cell size. Medium-sized foam cells (50-150 μm) were the most intensely stained. This IR was also observed in the nuclei of foam cells and VSMCs. These findings may provide a basis for understanding the association of HMGB1 with atherosclerotic lesions of the cerebral and carotid arteries, and for constructing strategies to counteract atherosclerosis with anti-HMGB1 antibody.
The examinations of microorganisms by correlation optics method
NASA Astrophysics Data System (ADS)
Bilyi, Olexander I.
2004-06-01
In report described methods of correlation optics, which are based on the analysis of intensity changes of quasielastic light scattering by micro-organisms and allow the type of correlation function to obtain information about the size of dispersive particles. The principle of new optical method of verification is described. In this method the gauging of intensity of an indirect illumination is carried out by static spectroscopy and processing of observed data by a method of correlation spectroscopy. The given mode of gauging allows measuring allocation of micro-organisms in size interval of 0.1 - 10.0 microns. In the report results of examinations of cultures Pseudomonas aeruginosa, Escherichia coli, Micrococcus lutteus, Lamprocystis and Triocapsa bacteriachlorofil are considered.
2010-01-01
Background Previous studies have shown favourable results with intensive behavioural treatment for children with autism: evidence has emerged that treatment can be successfully implemented in a community setting and in adolescent participants. The aim of this study was to describe the 2-year adaptive functioning outcome of children and adolescents with autism treated intensively within the context of special autism centres, as well as to evaluate family satisfaction with the activity of the centres. Methods Sixty participants with autism (20 females and 40 males, aged between 4 and 18 years) attending the semi-residential rehabilitation centres for autism located in the Abruzzo region (Central Italy) were followed up and their adaptive functioning was evaluated both at baseline and after one and two years using the Vineland Adaptive Behaviour Scales (VABS). Parents' satisfaction with the service was evaluated using the Orbetello Satisfaction Scale for Children and Adolescent Mental Health. Results The increase in VABS scores was significant on several domains in the different gender and age categories. It is worth noting that male children had improved a great deal (roughly, an effect size >0.20) in the domains of communication, daily living and motor skills (effect sizes 0.34, 0.45 and 0.27 respectively) whereas in male adolescents, a notable increase in VABS scores was recorded in the domain of socialization only (effect size 0.23). On the other hand, adaptive behaviour in female children increased in the domains of socialization and motor skills (effect sizes 0.27 and 0.42 respectively) whereas in female adolescents, good results were achieved in the domains of daily living, socialization and motor skills (effect sizes 0.22, 0.26 and 0.20 respectively). The level of satisfaction of users of the service over time was found to be substantial, even when they had recently started the program. Conclusions Our results support the implementation of special autism treatment community centres, based on a parent co-directed rehabilitative, intensive and early intervention. Further experimental research designed to document the effectiveness of services provided to children and adolescents with autism in the community is recommended. PMID:20809976
NASA Astrophysics Data System (ADS)
Stern, Daniel P.
The vertical structure of the tangential wind field in tropical cyclones is investigated through observations, theory, and numerical simulations. First, a dataset of Doppler radar wind swaths obtained from NOAA/AOML/HRD is used to create azimuthal mean tangential wind fields for 7 storms on 17 different days. Three conventional wisdoms of vertical structure are reexamined: the outward slope of the Radius of Maximum Winds (RMW) decreases with increasing intensity, the slope increases with the size of the RMW, and the RMW is a surface of constant absolute angular momentum (M). The slopes of the RMW and of M surfaces are objectively determined. The slopes are found to increase linearly with the size of the low-level RMW, and to be independent of the intensity of the storm. While the RMW is approximately an M surface, M systematically decreases with height along the RMW. The steady-state analytical theory of Emanuel (1986) is shown to make specific predictions regarding the vertical structure of tropical cyclones. It is found that in this model, the slope of the RMW is a linear function of its size and is independent of intensity, and that the RMW is almost exactly an M surface. A simple time-dependent model which is governed by the same assumptions as the analytical theory yields the same results. Idealized hurricane simulations are conducted using the Weather Research and Forecasting (WRF) model. The assumptions of Emanuel's theory, slantwise moist neutrality and thermal wind balance, are both found to be violated. Nevertheless, the vertical structure of the wind field itself is generally well predicted by the theory. The percentage rate at which the winds decay with height is found to be nearly independent of both size and intensity, in agreement with observations and theory. Deviations from this decay profile are shown to be due to gradient wind imbalance. The slope of the RMW increases linearly with its size, but is systematically too large compared to observations. Also in contrast to observations, M generally increases with height along the RMW.
[A new method of processing quantitative PCR data].
Ke, Bing-Shen; Li, Guang-Yun; Chen, Shi-Min; Huang, Xiang-Yan; Chen, Ying-Jian; Xu, Jun
2003-05-01
Today standard PCR can't satisfy the need of biotechnique development and clinical research any more. After numerous dynamic research, PE company found there is a linear relation between initial template number and cycling time when the accumulating fluorescent product is detectable.Therefore,they developed a quantitative PCR technique to be used in PE7700 and PE5700. But the error of this technique is too great to satisfy the need of biotechnique development and clinical research. A better quantitative PCR technique is needed. The mathematical model submitted here is combined with the achievement of relative science,and based on the PCR principle and careful analysis of molecular relationship of main members in PCR reaction system. This model describes the function relation between product quantity or fluorescence intensity and initial template number and other reaction conditions, and can reflect the accumulating rule of PCR product molecule accurately. Accurate quantitative PCR analysis can be made use this function relation. Accumulated PCR product quantity can be obtained from initial template number. Using this model to do quantitative PCR analysis,result error is only related to the accuracy of fluorescence intensity or the instrument used. For an example, when the fluorescence intensity is accurate to 6 digits and the template size is between 100 to 1,000,000, the quantitative result accuracy will be more than 99%. The difference of result error is distinct using same condition,same instrument but different analysis method. Moreover,if the PCR quantitative analysis system is used to process data, it will get result 80 times of accuracy than using CT method.
NASA Astrophysics Data System (ADS)
Sekelsky, Stephen Michael
1995-11-01
The Microwave Remote Sensing Laboratory (MIRSL) st the University of Massachusetts has developed a unique single antenna, dual-frequency polarimetric Cloud Profiling Radar System (CPRS). This project was funded by the Department of Energy's Atmospheric Radiation Measurement (ARM) program, and was intended to help fill the void of ground-based remote sensors capable of characterizing cloud microphysical properties. CPRS is unique in that it can simultaneously measure the complex power backscattered from clouds at 33 GHz and 95 GHz through the same aperture. Both the 33 GHz and 95 GHz channels can transmit pulse-to-pulse selectable vertical or horizontal polarization, and simultaneously record both the copolarized and crosspolarized backscatter. CPRS Doppler, polarimetric and dual-wavelength reflectivity measurements combined with in situ cloud measurements should lead to the development of empirical models that can more accurately classify cloud-particle phase and habit, and make better quantitative estimates of particle size distribution parameters. This dissertation describes the CPRS hardware, and presents colocated 33 GHz and 95 GHz measurements that illustrate the use of dual-frequency measurements to estimate particle size when Mie scattering, is observed in backscatter from rain and ice-phase clouds. Polarimetric measurements are presented as a means of discriminating cloud phase (ice-water) and estimating crystal shape in cirrus clouds. Polarimetric and dual-wavelength observations of insects are also presented with a brief discussion of their impact on the interpretation of precipitation and liquid cloud measurements. In precipitation, Diermendjian's equations for Mie backscatter (1) and the Marshal-Palmer drop-size distribution are used to develop models relating differences in the reflectivity and mean velocity at 33 GHz and 95 GHz to the microphysical parameters of rain. These models are then used to estimate mean droplet size from CPRS measurements of drizzle, which were collected in July, 1993 during the system's first field test in Lincoln, NE. The dissertation also presents cirrus cloud and other measurements collected during the DOE-sponsored Remote Cloud Sensing Intensive Operations Period (RCS-IOP) experiment in April, 1994. Zenith-pointing cirrus measurements show small differences in 33 GHz and 95 GHz reflectivity, as models have predicted (2). Depolarization was also detected in a few cases when ice crystals precipitated from the base of a cloud. On May 29, 1994 CPRS observed a convective storm that produced a cirrus anvil cloud and hail. These storms are one 'engine' producing cirrus clouds and are currently a topic of intensive research by climatologists. Both zenith-pointing and range-height data formats are presented. Measurements of depolarization above the melting/layer are compared to in situ observations of particle size and shape. The RCS-IOP experiment also provided a first opportunity to verify our calibration with aircraft in situ measurements, and to compare our cloud measurements to those collected by other remote sensors. (Abstract shortened by UMI.).
The role of event water, a rapid shallow flow component, and catchment size in summer stormflow
Brown, V.A.; McDonnell, Jeffery J.; Burns, Douglas A.; Kendall, C.
1999-01-01
Seven nested headwater catchments (8 to 161 ha) were monitored during five summer rain events to evaluate storm runoff components and the effect of catchment size on water sources. Two-component isotopic hydrograph separation showed that event-water contributions near the time of peakflow ranged from 49% to 62% in the 7 catchments during the highest intensity event. The proportion of event water in stormflow was greater than could be accounted for by direct precipitation onto saturated areas. DOC concentrations in stormflow were strongly correlated with stream 18O composition. Bivariate mixing diagrams indicated that the large event water contributions were likely derived from flow through the soil O-horizon. Results from two-tracer, three-component hydrograph separations showed that the throughfall and O-horizon soil-water components together could account for the estimated contributions of event water to stormflow. End-member mixing analysis confirmed these results. Estimated event-water contributions were inversely related to catchment size, but the relation was significant for only the event with greatest rainfall intensity. Our results suggest that perched, shallow subsurface flow provides a substantial contribution to summer stormflow in these small catchments, but the relative contribution of this component decreases with catchment size.Seven nested headwater catchments (8 to 161 ha) were monitored during five summer rain events to evaluate storm runoff components and the effect of catchment size on water sources. Two-component isotopic hydrograph separation showed that event-water contributions near the time of peakflow ranged from 49% to 62% in the 7 catchments during the highest intensity event. The proportion of event water in stormflow was greater than could be accounted for by direct precipitation onto saturated areas. DOC concentrations in stormflow were strongly correlated with stream 18O composition. Bivariate mixing diagrams indicated that the large event water contributions were likely derived from flow through the soil O-horizon. Results from two-tracer, three-component hydrograph separations showed that the throughfall and O-horizon soil-water components together could account for the estimated contributions of event water to stormflow. End-member mixing analysis confirmed these results. Estimated event-water contributions were inversely related to catchment size, but the relation was significant for only the event with greatest rainfall intensity. Our results suggest that perched, shallow subsurface flow provides a substantial contribution to summer stormflow in these small catchments, but the relative contribution of this component decreases with catchment size.
Static Grain Growth in Contact Metamorphic Calcite: A Cathodoluminescence Study.
NASA Astrophysics Data System (ADS)
Vogt, B.; Heilbronner, R.; Herwegh, M.; Ramseyer, K.
2009-04-01
In the Adamello contact aureole, monomineralic mesozoic limestones were investigated in terms of grain size evolution and compared to results on numerical modeling performed by Elle. The sampled area shows no deformation and therefore represents an appropriate natural laboratory for the study of static grain growth (Herwegh & Berger, 2003). For this purpose, samples were collected at different distances to the contact to the pluton, covering a temperature range between 270 to 630°C. In these marbles, the grain sizes increase with temperature from 5 µm to about 1 cm as one approaches the contact (Herwegh & Berger, 2003). In some samples, photomicrographs show domains of variable cathodoluminescence (CL) intensities, which are interpreted to represent growth zonations. Microstructures show grains that contain cores and in some samples even several growth stages. The cores are usually not centered and the zones not concentric. They may be in touch with grain boundaries. These zonation patterns are consistent within a given aggregate but differ among the samples even if they come from the same location. Relative CL intensities depend on the Mn/Fe ratio. We assume that changes in trace amounts of Mn/Fe must have occurred during the grain size evolution, preserving local geochemical trends and their variations with time. Changes in Mn/Fe ratios can either be explained by (a) locally derived fluids (e.g. hydration reactions of sheet silicate rich marbles in the vicinity) or (b) by the infiltration of the calcite aggregates by externally derived (magmatic?) fluids. At the present stage, we prefer a regional change in fluid composition (b) because the growth zonations only occur at distances of 750-1250 m from the pluton contact (350-450°C). Closer to the contact, neither zonations nor cores were found. At larger distances, CL intensities differ from grain to grain, revealing diagenetic CL patterns that were incompletely recrystallized by grain growth. The role of infiltration of magmatic fluids is also manifest in the vicinity of dikes, where intense zonation patterns are prominent in the marbles. The software Elle was developed to simulate microstructural evolution in rocks. The numerical model with the title "Grain boundary sweeping" was performed by M. Jessell and was found on http://www.materialsknowledge.org/elle. It displays the grain size evolution and the development of growth zonations during grain boundary migration of a 2D foam structure. This simulation was chosen because the driving force is the minimization of isotropic surface energies. It will be compared to the natural microstructures. At the last stage of the simulation the average grain and core sizes have increased. All, even the smallest grains, show growth zonations. Grains can be divided into two groups: (a) initially larger grains, increasing their grain size and maintaining their core size and (b) initially smaller grains with decreasing grain and decreasing core size. Group (a) grains show large areas swept by grain boundaries into the direction of small grains. Grain boundaries between large grains move more slowly. Their cores do not touch any grain boundaries. Cores of group (b) grains are in contact with the grain boundary network and are on the way to be consumed. In the numerical model and in the natural example similar features can be observed: The cores are not necessarily centered, the zonations are not necessarily concentric and some of the cores touch the grain boundary network. In the simulation, grain boundary migration velocity between large grains is smaller than between a large and a small grain. From this we would predict that - given enough time - a well sorted grain size distribution of increased grain size could be generated. But since many small grains occur we infer that this equilibrium has not been obtained. Analytical results of some natural samples that could be analyzed up to now indicate a relatively well sorted grain size distribution suggesting a more mature state of static grain growth. In comparison to the simulation, grain and core boundaries in the marbles are not always straight. For lobate grain boundaries the surface area has not been minimized in respect to the grain size. An explanation for this might be grain boundary pinning or a local dynamic overprint. Some cores and growth zones in the investigated calcites show a continuous change in luminescence. This is interpreted to be an effect of late diffusion within the grain and/or a continuous change of fluid composition and supply. The absence of zonation in samples close to the contact might be explained by fast grain growth due to high temperatures and/or fast fluid transport. Possibly, this is combined with an enhanced component of volume diffusion. Thus concentration variations of Mn/Fe are diminished and not visible in form of a growth zonation. Herwegh M, Berger A (2003) Differences in grain growth of calcite: a field-based modeling approach. Contr. Min. Pet. 145: 600-611
Gabbett, Tim J; Abernethy, Bruce; Jenkins, David G
2012-02-01
The purpose of this study was to investigate the effect of changes in field size on the physiological and skill demands of small-sided games in elite junior and senior rugby league players. Sixteen elite senior rugby league players ([mean ± SE] age, 23.6 ± 0.5 years) and 16 elite junior rugby league players ([mean ± SE] age, 17.3 ± 0.3 years) participated in this study. On day 1, 2 teams played an 8-minute small-sided game on a small field (10-m width × 40-m length), whereas the remaining 2 teams played the small-sided game on a larger sized field (40-m width × 70-m length). On day 2, the groups were crossed over. Movement was recorded by a global positioning system unit sampling at 5 Hz. Games were filmed to count the number of possessions and the number and quality of disposals. The games played on a larger field resulted in a greater (p < 0.05) total distance covered, and distances covered in moderate, high, and very-high velocity movement intensities. Senior players covered more distance at moderate, high, and very-high intensities, and less distance at low and very-low intensities during small-sided games than junior players. Although increasing field size had no significant influence (p > 0.05) over the duration of recovery periods for junior players, larger field size significantly reduced (p < 0.05) the amount of short-, moderate-, and long-duration recovery periods in senior players. No significant between-group differences (p > 0.05) were detected for games played on a small or large field for the number or quality of skill involvements. These results suggest that increases in field size serve to increase the physiological demands of small-sided games but have minimal influence over the volume or quality of skill executions in elite rugby league players.
Cheng, Ren-Chung; Zhang, Shichang; Chen, Yu-Chun; Lee, Chia-Yi; Chou, Yi-Ling; Ye, Hui-Ying; Piorkowski, Dakota; Liao, Chen-Pan; Tso, I-Min
2017-06-15
While molting occurs in the development of many animals, especially arthropods, post-maturity molting (PMM, organisms continue to molt after sexual maturity) has received little attention. The mechanism of molting has been studied intensively; however, the mechanism of PMM remains unknown although it is suggested to be crucial for the development of body size. In this study, we investigated factors that potentially induce PMM in the golden orb-web spider Nephila pilipes , which has the greatest degree of sexual dimorphism among terrestrial animals. We manipulated the mating history and the nutrient consumption of the females to examine whether they affect PMM. The results showed that female spiders under low nutrition were more likely to molt as adults, and mating had no significant influence on the occurrence of PMM. Moreover, spiders that underwent PMM lived longer than those that did not and their body sizes were significantly increased. Therefore, we concluded that nutritional condition rather than mating history affect PMM. © 2017. Published by The Company of Biologists Ltd.
Variation in ancient Egyptian stature and body proportions.
Zakrzewski, Sonia R
2003-07-01
Stature and the pattern of body proportions were investigated in a series of six time-successive Egyptian populations in order to investigate the biological effects on human growth of the development and intensification of agriculture, and the formation of state-level social organization. Univariate analyses of variance were performed to assess differences between the sexes and among various time periods. Significant differences were found both in stature and in raw long bone length measurements between the early semipastoral population and the later intensive agricultural population. The size differences were greater in males than in females. This disparity is suggested to be due to greater male response to poor nutrition in the earlier populations, and with the increasing development of social hierarchy, males were being provisioned preferentially over females. Little change in body shape was found through time, suggesting that all body segments were varying in size in response to environmental and social conditions. The change found in body plan is suggested to be the result of the later groups having a more tropical (Nilotic) form than the preceding populations. Copyright 2003 Wiley-Liss, Inc.
Ramírez-Ponce, Andrés; Garfias-Lozano, Gabriela; Contreras-Ramos, Atilano
2017-01-01
The origin and function of exaggerated traits exhibited by a great number of species with sexual dimorphism remain largely unexplored. The usual model considered as the evolutionary mechanism for the development of these structures is sexual selection. The nature of growth of the postocular flange (POF) in three species of the dobsonfly genus Platyneuromus (Megaloptera, Corydalidae, Corydalinae) is analyzed to explore sexual size dimorphism and allometric scaling. Results involve positive allometry of POF in males of two species, and negative allometry in males of one species, in general with a female-biased sexual dimorphism. We suggest an ancestral condition of dual incipient ornamentation in Platyneuromus, with a subsequent departure of size and shape of POF in males, triggered by sexual selection. Different sexual selection intensities may explain the parallel or divergent growth of POF within the scheme of dual ornamentation. Empirical behavioral data as well as a phylogenetic framework are necessary to clarify possible causes of phenotypic development, time of origin, and evolution of the POF. PMID:28212437
Manufacturing information system
NASA Astrophysics Data System (ADS)
Allen, D. K.; Smith, P. R.; Smart, M. J.
1983-12-01
The size and cost of manufacturing equipment has made it extremely difficult to perform realistic modeling and simulation of the manufacturing process in university research laboratories. Likewise the size and cost factors, coupled with many uncontrolled variables of the production situation has even made it difficult to perform adequate manufacturing research in the industrial setting. Only the largest companies can afford manufacturing research laboratories; research results are often held proprietary and seldom find their way into the university classroom to aid in education and training of new manufacturing engineers. It is the purpose for this research to continue the development of miniature prototype equipment suitable for use in an integrated CAD/CAM Laboratory. The equipment being developed is capable of actually performing production operations (e.g. drilling, milling, turning, punching, etc.) on metallic and non-metallic workpieces. The integrated CAD/CAM Mini-Lab is integrating high resolution, computer graphics, parametric design, parametric N/C parts programmings, CNC machine control, automated storage and retrieval, with robotics materials handling. The availability of miniature CAD/CAM laboratory equipment will provide the basis for intensive laboratory research on manufacturing information systems.
Evidence for dust grain growth in young circumstellar disks.
Throop, H B; Bally, J; Esposito, L W; McCaughrean, M J
2001-06-01
Hundreds of circumstellar disks in the Orion nebula are being rapidly destroyed by the intense ultraviolet radiation produced by nearby bright stars. These young, million-year-old disks may not survive long enough to form planetary systems. Nevertheless, the first stage of planet formation-the growth of dust grains into larger particles-may have begun in these systems. Observational evidence for these large particles in Orion's disks is presented. A model of grain evolution in externally irradiated protoplanetary disks is developed and predicts rapid particle size evolution and sharp outer disk boundaries. We discuss implications for the formation rates of planetary systems.
NASA Astrophysics Data System (ADS)
Hong, Ruijin; Shao, Wen; Ji, Jialin; Tao, Chunxian; Zhang, Dawei
2018-06-01
Silver thin films with linear variable thickness were deposited at room temperature. The corresponding tunability of optical properties and Raman scattering intensity were realized by thermal annealing process. With the thickness increasing, the topography of as-annealed silver thin films was observed to develop from discontinued nanospheres into continuous structure with a redshift of the surface plasmon resonance wavelength in visible region. Both the various nanosphere sizes and states of aggregation of as-annealed silver thin films contributed to significantly increasing the sensitivity of surface enhanced Raman scattering (SERS).
Enabling Large-Scale Biomedical Analysis in the Cloud
Lin, Ying-Chih; Yu, Chin-Sheng; Lin, Yen-Jen
2013-01-01
Recent progress in high-throughput instrumentations has led to an astonishing growth in both volume and complexity of biomedical data collected from various sources. The planet-size data brings serious challenges to the storage and computing technologies. Cloud computing is an alternative to crack the nut because it gives concurrent consideration to enable storage and high-performance computing on large-scale data. This work briefly introduces the data intensive computing system and summarizes existing cloud-based resources in bioinformatics. These developments and applications would facilitate biomedical research to make the vast amount of diversification data meaningful and usable. PMID:24288665
Trophic strategies, animal diversity and body size
Lafferty, Kevin D.; Kuris, Armand M.
2002-01-01
A primary difference between predators and parasites is the number of victims that an individual attacks throughout a life-history stage. A key division within natural enemies is whether a successful attack eliminates the fitness of the prey or the host. A third distinctive axis for parasites is whether the host must die to further parasite development. The presence or absence of intensity-dependent pathology is a fourth factor that separates macroparasites from microparasites; this also distinguishes between social and solitary predators. Combining these four dichotomies defines seven types of parasitism, seven corresponding parasites, three forms of predation and, when one considers obligate and facultative combinations of these forms, four types of predator. Here, we argue that the energetics underlying the relative and absolute sizes of natural enemies and their victims is the primary selective factor responsible for the evolution of these different trophic strategies.
The effects of inter-cavity separation on optical coupling in dielectric bispheres.
Ashili, Shashanka P; Astratov, Vasily N; Sykes, E Charles H
2006-10-02
The optical coupling between two size-mismatched spheres was studied by using one sphere as a local source of light with whispering gallery modes (WGMs) and detecting the intensity of the light scattered by a second sphere playing the part of a receiver of electromagnetic energy. We developed techniques to control inter-cavity gap sizes between microspheres with ~30nm accuracy. We demonstrate high efficiencies (up to 0.2-0.3) of coupling between two separated cavities with strongly detuned eigenstates. At small separations (<1 microm) between the spheres, the mechanism of coupling is interpreted in terms of the Fano resonance between discrete level (true WGMs excited in a source sphere) and a continuum of "quasi"-WGMs with distorted shape which can be induced in the receiving sphere. At larger separations the spectra detected from the receiving sphere originate from scattering of the radiative modes.
Photoresponsive Passive Micromixers Based on Spiropyran Size-Tunable Hydrogels.
Ter Schiphorst, Jeroen; Melpignano, Giuseppe G; Amirabadi, Hossein Eslami; Houben, Menno H J M; Bakker, Sterre; den Toonder, Jaap M J; Schenning, Albertus P H J
2018-01-01
Microfluidic devices allow the manipulation of fluids down to the micrometer scale and are receiving a lot of attention for applications where low volumes and high throughputs are required. In these micro channels, laminar flow usually dominates, which requires long residence times of the fluids, limiting the flow speed and throughput. Here a switchable passive mixer has been developed to control mixing and to easily clean microchannels. The mixer is based on a photoresponsive spiropyran based hydrogel of which the dimensions can be tuned by changing the intensity of the light. The size-tunable gels have been used to fabricate a passive slanted groove mixer that can be switched off by light allowing to change mixing of microfluidics to non-mixed flows. These findings open new possibilities for multi-purpose microfluidic devices where mixers and valves can be tuned by light. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Development of composite calibration standard for quantitative NDE by ultrasound and thermography
NASA Astrophysics Data System (ADS)
Dayal, Vinay; Benedict, Zach G.; Bhatnagar, Nishtha; Harper, Adam G.
2018-04-01
Inspection of aircraft components for damage utilizing ultrasonic Non-Destructive Evaluation (NDE) is a time intensive endeavor. Additional time spent during aircraft inspections translates to added cost to the company performing them, and as such, reducing this expenditure is of great importance. There is also great variance in the calibration samples from one entity to another due to a lack of a common calibration set. By characterizing damage types, we can condense the required calibration sets and reduce the time required to perform calibration while also providing procedures for the fabrication of these standard sets. We present here our effort to fabricate composite samples with known defects and quantify the size and location of defects, such as delaminations, and impact damage. Ultrasonic and Thermographic images are digitally enhanced to accurately measure the damage size. Ultrasonic NDE is compared with thermography.
NASA Astrophysics Data System (ADS)
Li, Xin; Zhou, Shihong; Ma, Jing; Tan, Liying; Shen, Tao
2013-08-01
CMOS is a good candidate tracking detector for satellite optical communications systems with outstanding feature of sub-window for the development of APS (Active Pixel Sensor) technology. For inter-satellite optical communications it is critical to estimate the direction of incident laser beam precisely by measuring the centroid position of incident beam spot. The presence of detector noise results in measurement error, which degrades the tracking performance of systems. In this research, the measurement error of CMOS is derived taking consideration of detector noise. It is shown that the measurement error depends on pixel noise, size of the tracking sub-window (pixels number), intensity of incident laser beam, relative size of beam spot. The influences of these factors are analyzed by numerical simulation. We hope the results obtained in this research will be helpful in the design of CMOS detector satellite optical communications systems.
Interpixel crosstalk cancellation on holographic memory
NASA Astrophysics Data System (ADS)
Ishii, Toshiki; Fujimura, Ryushi
2017-09-01
In holographic memory systems, there have been no practical techniques to minimize interpixel crosstalk thus far. We developed an interpixel crosstalk cancellation technique using a checkerboard phase pattern with a phase difference of π/2, which can decrease the size of the spatial filter along the Fourier plane with the signal-to-noise ratio (SNR) kept high. This interpixel crosstalk cancellation technique is simple because it requires only one phase plate in the signal beam path. We verified the effect of such a cancellation technique by simulation. The improvement of SNR is maximized to 6.5 dB when the filter size specified in the Nyquist areal ratio is approximately 1.05 in ideal optical systems with no other fixed noise. The proposed technique can improve SNR by 0.85 in an assumed monocular architecture at an actual noise intensity. This improvement of SNR is very useful for realizing high-density recording or enhancing system robustness.
Airborne Laser Polar Nephelometer
NASA Technical Reports Server (NTRS)
Grams, Gerald W.
1973-01-01
A polar nephelometer has been developed at NCAR to measure the angular variation of the intensity of light scattered by air molecules and particles. The system has been designed for airborne measurements using outside air ducted through a 5-cm diameter airflow tube; the sample volume is that which is common to the intersection of a collimated source beam and the detector field of view within the airflow tube. The source is a linearly polarized helium-neon laser beam. The optical system defines a collimated field-of-view (0.5deg half-angle) through a series of diaphragms located behind a I72-mm focal length objective lens. A photomultiplier tube is located immediately behind an aperture in the focal plane of the objective lens. The laser beam is mechanically chopped (on-off) at a rate of 5 Hz; a two-channel pulse counter, synchronized to the laser output, measures the photomultiplier pulse rate with the light beam both on and off. The difference in these measured pulse rates is directly proportional to the intensity of the scattered light from the volume common to the intersection of the laser beam and the detector field-of-view. Measurements can be made at scattering angles from 15deg to 165deg with reference to the direction of propagation of the light beam. Intermediate angles are obtained by selecting the angular increments desired between these extreme angles (any multiple of 0.1deg can be selected for the angular increment; 5deg is used in normal operation). Pulses provided by digital circuits control a stepping motor which sequentially rotates the detector by pre-selected angular increments. The synchronous photon-counting system automatically begins measurement of the scattered-light intensity immediately after the rotation to a new angle has been completed. The instrument has been flown on the NASA Convair 990 airborne laboratory to obtain data on the complex index of refraction of atmospheric aerosols. A particle impaction device is operated simultaneously to collect particles from the same airflow tube used to make the scattered-light measurements. A size distribution function is obtained by analysis of the particles collected by the impaction device. Calculated values of the angular variation of the scattered-light intensity are obtained by applying Mie scattering theory to the observed size distribution function and assuming different values of the complex index of refraction of the particles. The calculated values are then compared with data on the actual variation of the scattered-light intensity obtained with the polar nephelometer. The most probable value of the complex refractive index is that which provides the best fit between the experimental light scattering data and the parameters calculated from the observed size distribution function.
Antimisting fuel breakup and flammability
NASA Technical Reports Server (NTRS)
Parikh, P.; Fleeter, R.; Sarohia, V.
1983-01-01
The breakup behavior and flammability of antimisting turbine fuels subjected to aerodynamic shear are investigated. Fuels tested were Jet A containing 0.3% FM-9 polymer at various levels of degradation ranging from virgin AMK to neat Jet A. The misting behavior of the fuels was quantified by droplet size distribution measurements. A technique based on high resolution laser photography and digital image processing of photographic records for rapid determination of droplet size distribution was developed. The flammability of flowing droplet-air mixtures was quantified by direct measurements of temperature rise in a flame established in the wake of a continuous ignition source. The temperature rise measurements were correlated with droplet size measurements. The flame anchoring phenomenon associated with the breakup of a liquid fuel in the wake of bluff body was shown to be important in the context of a survivable crash scenario. A pass/fail criterion for flammability testing of antimisting fuels, based on this flame-anchoring phenomenon, was proposed. The role of various ignition sources and their intensity in ignition and post-ignition behavior of antimisting fuels was also investigated.