Object-oriented technologies in a multi-mission data system

NASA Technical Reports Server (NTRS)

Murphy, Susan C.; Miller, Kevin J.; Louie, John J.

1993-01-01

The Operations Engineering Laboratory (OEL) at JPL is developing new technologies that can provide more efficient and productive ways of doing business in flight operations. Over the past three years, we have worked closely with the Multi-Mission Control Team to develop automation tools, providing technology transfer into operations and resulting in substantial cost savings and error reduction. The OEL development philosophy is characterized by object-oriented design, extensive reusability of code, and an iterative development model with active participation of the end users. Through our work, the benefits of object-oriented design became apparent for use in mission control data systems. Object-oriented technologies and how they can be used in a mission control center to improve efficiency and productivity are explained. The current research and development efforts in the JPL Operations Engineering Laboratory are also discussed to architect and prototype a new paradigm for mission control operations based on object-oriented concepts.

About the Frederick National Laboratory for Cancer Research | Frederick National Laboratory for Cancer Research

Cancer.gov

The Frederick National Laboratory is a Federally Funded Research and Development Center (FFRDC) sponsored by the National Cancer Institute (NCI) and currently operated by Leidos Biomedical Research, Inc. The laboratory addresses some of the most urge

Adaptation of Professional Skills in the Unit Operations Laboratory

ERIC Educational Resources Information Center

Rende, Deniz; Rende, Sevinc; Baysal, Nihat

2012-01-01

We introduce the design of three consecutive unit operations laboratory (UOL) courses that retain the academic rigor of the course while incorporating skills essential for professional careers, such as ability to propose ideas, develop practical solutions, participate in teamwork, meet deadlines, establish communication between technical support…

EPA LABORATORIES IMPLEMENT EMS PROGRAM

EPA Science Inventory

This paper highlights the breadth and magnitude of carrying out an effective Environmental Management System (EMS) program at the U.S. EPA's research and development laboratories. Federal research laboratories have unique operating challenges compared to more centralized industr...

LDRD 2016 Annual Report: Laboratory Directed Research and Development Program Activities

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hatton, D.

Each year, Brookhaven National Laboratory (BNL) is required to provide a program description and overview of its Laboratory Directed Research and Development Program (LDRD) to the Department of Energy (DOE) in accordance with DOE Order 413.2C dated October 22, 2015. This report provides a detailed look at the scientific and technical activities for each of the LDRD projects funded by BNL in FY 2016, as required. In FY 2016, the BNL LDRD Program funded 48 projects, 21 of which were new starts, at a total cost of $11.5M. The investments that BNL makes in its LDRD program support the Laboratory’smore » strategic goals. BNL has identified four Critical Outcomes that define the Laboratory’s scientific future and that will enable it to realize its overall vision. Two operational Critical Outcomes address essential operational support for that future: renewal of the BNL campus; and safe, efficient laboratory operations.« less

The Stem Cell Laboratory: Design, Equipment, and Oversight

PubMed Central

Wesselschmidt, Robin L.; Schwartz, Philip H.

2013-01-01

This chapter describes some of the major issues to be considered when setting up a laboratory for the culture of human pluripotent stem cells (hPSCs). The process of establishing a hPSC laboratory can be divided into two equally important parts. One is completely administrative and includes developing protocols, seeking approval, and establishing reporting processes and documentation. The other part of establishing a hPSC laboratory involves the physical plant and includes design, equipment and personnel. Proper planning of laboratory operations and proper design of the physical layout of the stem cell laboratory so that meets the scope of planned operations is a major undertaking, but the time spent upfront will pay long-term returns in operational efficiency and effectiveness. A well-planned, organized, and properly equipped laboratory supports research activities by increasing efficiency and reducing lost time and wasted resources. PMID:21822863

Laboratory Directed Research and Development Annual Report FY 2017

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sullivan, Kelly O.

A national laboratory must establish and maintain an environment in which creativity and innovation are encouraged and supported in order to fulfill its missions and remain viable in the long term. As such, multiprogram laboratories are given discretion to allocate a percentage of their operating budgets to support research and development projects that align to PNNL’s and DOE’s missions and support the missions of other federal agencies, including DHS, DOD, and others. DOE Order 413.2C sets forth DOE’s Laboratory Directed Research and Development (LDRD) policy and guidelines for DOE multiprogram laboratories, and it authorizes the national laboratories to allocate upmore » to 6 percent of their operating budgets to fund the program. LDRD is innovative research and development, selected by the Laboratory Director or his/her designee, for the purpose of maintaining the scientific and technological vitality of the Laboratory. The projects supported by LDRD funding all have demonstrable ties to DOE/DHS missions and may also be relevant to the missions of other federal agencies that sponsor work at the Laboratory. The program plays a key role in attracting the best and brightest scientific staff, which is needed to serve the highest priority DOE mission objectives. Individual project reports comprise the bulk of this LDRD report. The Laboratory focuses its LDRD research on scientific assets that often address more than one scientific discipline.« less

Laboratory Directed Research and Development Annual Report FY 2016

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sullivan, Kelly O.

A national laboratory must establish and maintain an environment in which creativity and innovation are encouraged and supported in order to fulfill its missions and remain viable in the long term. As such, multiprogram laboratories are given discretion to allocate a percentage of their operating budgets to support research and development projects that align to PNNL’s and DOE’s missions and support the missions of other federal agencies, including DHS, DOD, and others. DOE Order 413.2C sets forth DOE’s Laboratory Directed Research and Development (LDRD) policy and guidelines for DOE multiprogram laboratories, and it authorizes the national laboratories to allocate upmore » to 6 percent of their operating budgets to fund the program. LDRD is innovative research and development, selected by the Laboratory Director or his/her designee, for the purpose of maintaining the scientific and technological vitality of the Laboratory. The projects supported by LDRD funding all have demonstrable ties to DOE/DHS missions and may also be relevant to the missions of other federal agencies that sponsor work at the Laboratory. The program plays a key role in attracting the best and brightest scientific staff, which is needed to serve the highest priority DOE mission objectives. Individual project reports comprise the bulk of this LDRD report. The Laboratory focuses its LDRD research on scientific assets that often address more than one scientific discipline.« less

Operating environmental laboratories--an overview of analysis equipment procurement and management.

PubMed

Pandya, G H; Shinde, V M; Kanade, G S; Kondawar, V K

2003-10-01

Management of equipment in an environmental laboratory requires planning involving assessment of the workload on a particular equipment, establishment of criteria and specification for the purchase of equipment, creation of infrastructure for installation and testing of the equipment, optimization of analysis conditions, development of preventive maintenance procedures and establishment of in-house repair facilities. The paper reports the results of such an analysis carried for operating environmental laboratories associated with R& D work, serving as an Govt. laboratory or attached to an Industry for analysing industrial emissions.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bates, L.D.

Oak Ridge National Laboratory (ORNL) is a principle Department of Energy (DOE) Research Institution operated by the Union Carbide Corporation - Nuclear Division (UCC-ND) under direction of the DOE Oak Ridge Operations Office (DOE-ORO). The Laboratory was established in east Tennessee, near what is now the city of Oak Ridge, in the mid 1940s as a part of the World War II effort to develop a nuclear weapon. Since its inception, disposal of radioactively contaminated materials, both solid and liquid, has been an integral part of Laboratory operations. The purpose of this document is to provide a detailed description ofmore » the ORNL Solid Waste Storage Areas, to describe the practice and procedure of their operation, and to address the health and safety impacts and concerns of that operation.« less

A Methodical Approach to the Creation, Operation, and Enhancement of a General-use Microcomputer Laboratory.

ERIC Educational Resources Information Center

Seilheimer, Steven D.

1988-01-01

Outlines procedures for developing a microcomputer laboratory for use by students in an academic organization, based on experiences at Niagara University. The four phases described include: (1) needs assessment; (2) establishment, including software and hardware selection and physical facilities; (3) operation, including staffing, maintenance,…

The WHO/PEPFAR collaboration to prepare an operations manual for HIV prevention, care, and treatment at primary health centers in high-prevalence, resource-constrained settings: defining laboratory services.

PubMed

Spira, Thomas; Lindegren, Mary Lou; Ferris, Robert; Habiyambere, Vincent; Ellerbrock, Tedd

2009-06-01

The expansion of HIV/AIDS care and treatment in resource-constrained countries, especially in sub-Saharan Africa, has generally developed in a top-down manner. Further expansion will involve primary health centers where human and other resources are limited. This article describes the World Health Organization/President's Emergency Plan for AIDS Relief collaboration formed to help scale up HIV services in primary health centers in high-prevalence, resource-constrained settings. It reviews the contents of the Operations Manual developed, with emphasis on the Laboratory Services chapter, which discusses essential laboratory services, both at the center and the district hospital level, laboratory safety, laboratory testing, specimen transport, how to set up a laboratory, human resources, equipment maintenance, training materials, and references. The chapter provides specific information on essential tests and generic job aids for them. It also includes annexes containing a list of laboratory supplies for the health center and sample forms.

Flight and mission operations support for Voyager spacecraft launching and Viking-Mars mission

NASA Technical Reports Server (NTRS)

1978-01-01

The activities of the Jet Propulsion Laboratory during fiscal year 1976-1977 are summarized. Areas covered include ongoing and planned flight projects, DSN operations and development, research and advanced development in science and engineering, and civil systems projects. In addition, administrative and operational facilities and developments are described.

Design of a Clinical Information Management System to Support DNA Analysis Laboratory Operation

PubMed Central

Dubay, Christopher J.; Zimmerman, David; Popovich, Bradley

1995-01-01

The LabDirector system has been developed at the Oregon Health Sciences University to support the operation of our clinical DNA analysis laboratory. Through an iterative design process which has spanned two years, we have produced a system that is both highly tailored to a clinical genetics production laboratory and flexible in its implementation, to support the rapid growth and change of protocols and methodologies in use in the field. The administrative aspects of the system are integrated with an enterprise schedule management system. The laboratory side of the system is driven by a protocol modeling and execution system. The close integration between these two aspects of the clinical laboratory facilitates smooth operations, and allows management to accurately measure costs and performance. The entire application has been designed and documented to provide utility to a wide range of clinical laboratory environments.

Strategic establishment of an International Pharmacology Specialty Laboratory in a resource-limited setting.

PubMed

Mtisi, Takudzwa J; Maponga, Charles; Monera-Penduka, Tsitsi G; Mudzviti, Tinashe; Chagwena, Dexter; Makita-Chingombe, Faithful; DiFranchesco, Robin; Morse, Gene D

2018-01-01

A growing number of drug development studies that include pharmacokinetic evaluations are conducted in regions lacking a specialised pharmacology laboratory. This necessitated the development of an International Pharmacology Specialty Laboratory (IPSL) in Zimbabwe. The aim of this article is to describe the development of an IPSL in Zimbabwe. The IPSL was developed collaboratively by the University of Zimbabwe and the University at Buffalo Center for Integrated Global Biomedical Sciences. Key stages included infrastructure development, establishment of quality management systems and collaborative mentorship in clinical pharmacology study design and chromatographic assay development and validation. Two high performance liquid chromatography instruments were donated by an instrument manufacturer and a contract research organisation. Laboratory space was acquired through association with the Zimbabwe national drug regulatory authority. Operational policies, standard operating procedures and a document control system were established. Scientists and technicians were trained in aspects relevant to IPSL operations. A high-performance liquid chromatography method for nevirapine was developed with the guidance of the Clinical Pharmacology Quality Assurance programme and approved by the assay method review programme. The University of Zimbabwe IPSL is engaged with the United States National Institute of Allergy and Infectious Diseases Division of AIDS research networks and is poised to begin drug assays and pharmacokinetic analyses. An IPSL has been successfully established in a resource-limited setting through the efforts of an external partnership providing technical guidance and motivated internal faculty and staff. Strategic partnerships were beneficial in navigating challenges leading to laboratory development and training new investigators. The IPSL is now engaged in clinical pharmacology research.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rodriguez, J.R.; Ahrens, J.S.; Lowe, D.L.

Throughout the years, Sandia National Laboratories (SNL) has performed various laboratory evaluations of entry control devices, including biometric identity verifiers. The reports which resulted from this testing have been very well received by the physical security community. This same community now requires equally informative field study data. To meet this need we have conducted a field study in an effort to develop the tools and methods which our customers can use to translate laboratory data into operational field performance. The field testing described in this report was based on the Recognition Systems Inc.`s (RSI) model ID3D HandKey biometric verifier. Thismore » device was selected because it is referenced in DOE documents such as the Guide for Implementation of the DOE Standard Badge and is the de facto biometric standard for the DOE. The ID3D HandKey is currently being used at several DOE sites such as Hanford, Rocky Flats, Pantex, Savannah River, and Idaho Nuclear Engineering Laboratory. The ID3D HandKey was laboratory tested at SNL. It performed very well during this test, exhibiting an equal error point of 0.2 percent. The goals of the field test were to identify operational characteristics and design guidelines to help system engineers translate laboratory data into field performance. A secondary goal was to develop tools which could be used by others to evaluate system effectiveness or improve the performance of their systems. Operational characteristics were determined by installing a working system and studying its operation over a five month period. Throughout this test we developed tools which could be used by others to similarly gauge system effectiveness.« less

Definition of Life Sciences laboratories for shuttle/Spacelab. Volume 1: Executive summary

NASA Technical Reports Server (NTRS)

1975-01-01

Research requirements and the laboratories needed to support a Life Sciences research program during the shuttle/Spacelab era were investigated. A common operational research equipment inventory was developed to support a comprehensive but flexible Life Sciences program. Candidate laboratories and operational schedules were defined and evaluated in terms of accomodation with the Spacelab and overall program planning. Results provide a firm foundation for the initiation of a life science program for the shuttle era.

The Case for Laboratory Developed Procedures

PubMed Central

Sabatini, Linda M.; Tsongalis, Gregory J.; Caliendo, Angela M.; Olsen, Randall J.; Ashwood, Edward R.; Bale, Sherri; Benirschke, Robert; Carlow, Dean; Funke, Birgit H.; Grody, Wayne W.; Hayden, Randall T.; Hegde, Madhuri; Lyon, Elaine; Pessin, Melissa; Press, Richard D.; Thomson, Richard B.

2017-01-01

An explosion of knowledge and technology is revolutionizing medicine and patient care. Novel testing must be brought to the clinic with safety and accuracy, but also in a timely and cost-effective manner, so that patients can benefit and laboratories can offer testing consistent with current guidelines. Under the oversight provided by the Clinical Laboratory Improvement Amendments, laboratories have been able to develop and optimize laboratory procedures for use in-house. Quality improvement programs, interlaboratory comparisons, and the ability of laboratories to adjust assays as needed to improve results, utilize new sample types, or incorporate new mutations, information, or technologies are positive aspects of Clinical Laboratory Improvement Amendments oversight of laboratory-developed procedures. Laboratories have a long history of successful service to patients operating under Clinical Laboratory Improvement Amendments. A series of detailed clinical examples illustrating the quality and positive impact of laboratory-developed procedures on patient care is provided. These examples also demonstrate how Clinical Laboratory Improvement Amendments oversight ensures accurate, reliable, and reproducible testing in clinical laboratories. PMID:28815200

The Plymouth Laboratory and the institutionalization of experimental zoology in Britain in the 1920s.

PubMed

Erlingsson, Steindór J

2009-01-01

The Plymouth Laboratory of the Marine Biological Association of the United Kingdom (1884) was founded in 1888. In addition to conducting morphological and other biological research, the founders of the laboratory aimed at promoting research in experimental zoology which will be used in this paper as a synonym for e.g. experimental embryology, comparative physiology or general physiology. This dream was not fully realized until 1920. The Great War and its immediate aftermath had a positive impact on the development of the Plymouth Laboratory. The war greatly upset the operation of the Zoological Station in Naples and the ensuing crisis in its operations was closely related to the establishment of the physiological department in Plymouth in 1920. Two other key factors in the Plymouth story were the establishment of the Development Fund in 1909, which began contributing funds to the Plymouth Laboratory in 1912, and the patronage of the Cambridge zoologist George P. Bidder (1863-1954). This paper will focus on the combined influence of the Development Fund and Bidder on the development of the Plymouth Laboratory from around 1902 through the early 1920s, and the important role the laboratory played in promoting experimental zoology in Britain in the 1920s.

Smoke Detector Technology.

ERIC Educational Resources Information Center

Powell, Pamela, Ed.; Portugill, Jestyn, Ed.

This manual, one in a series developed for public education, provides information on smoke detector selection, installation, operation, and maintenance. For the prospective buyer, the importance of looking for the seal of a recognized national testing laboratory--such as Underwriters' Laboratories, Inc. (UL)--indicating adequate laboratory testing…

A Multi-User Remote Academic Laboratory System

ERIC Educational Resources Information Center

Barrios, Arquimedes; Panche, Stifen; Duque, Mauricio; Grisales, Victor H.; Prieto, Flavio; Villa, Jose L.; Chevrel, Philippe; Canu, Michael

2013-01-01

This article describes the development, implementation and preliminary operation assessment of Multiuser Network Architecture to integrate a number of Remote Academic Laboratories for educational purposes on automatic control. Through the Internet, real processes or physical experiments conducted at the control engineering laboratories of four…

Nuclear criticality safety staff training and qualifications at Los Alamos National Laboratory

DOE Office of Scientific and Technical Information (OSTI.GOV)

Monahan, S.P.; McLaughlin, T.P.

1997-05-01

Operations involving significant quantities of fissile material have been conducted at Los Alamos National Laboratory continuously since 1943. Until the advent of the Laboratory`s Nuclear Criticality Safety Committee (NCSC) in 1957, line management had sole responsibility for controlling criticality risks. From 1957 until 1961, the NCSC was the Laboratory body which promulgated policy guidance as well as some technical guidance for specific operations. In 1961 the Laboratory created the position of Nuclear Criticality Safety Office (in addition to the NCSC). In 1980, Laboratory management moved the Criticality Safety Officer (and one other LACEF staff member who, by that time, wasmore » also working nearly full-time on criticality safety issues) into the Health Division office. Later that same year the Criticality Safety Group, H-6 (at that time) was created within H-Division, and staffed by these two individuals. The training and education of these individuals in the art of criticality safety was almost entirely self-regulated, depending heavily on technical interactions between each other, as well as NCSC, LACEF, operations, other facility, and broader criticality safety community personnel. Although the Los Alamos criticality safety group has grown both in size and formality of operations since 1980, the basic philosophy that a criticality specialist must be developed through mentoring and self motivation remains the same. Formally, this philosophy has been captured in an internal policy, document ``Conduct of Business in the Nuclear Criticality Safety Group.`` There are no short cuts or substitutes in the development of a criticality safety specialist. A person must have a self-motivated personality, excellent communications skills, a thorough understanding of the principals of neutron physics, a safety-conscious and helpful attitude, a good perspective of real risk, as well as a detailed understanding of process operations and credible upsets.« less

Emergency Procedure Training for Reactor Operators at the High Flux Beam Reactor for Brookhaven National Laboratory.

ERIC Educational Resources Information Center

Reyer, Ronald

A project was conducted to analyze, design, develop, implement, and evaluate an instructional unit intended to improve the diagnostic skills of operating personnel in responding to abnormal and emergency conditions at the High Flux Beam Reactor at Brookhaven National Laboratory. Research was conducted on the occurrence of emergencies at similar…

National Laboratory Planning: Developing Sustainable Biocontainment Laboratories in Limited Resource Areas.

PubMed

Yeh, Kenneth B; Adams, Martin; Stamper, Paul D; Dasgupta, Debanjana; Hewson, Roger; Buck, Charles D; Richards, Allen L; Hay, John

2016-01-01

Strategic laboratory planning in limited resource areas is essential for addressing global health security issues. Establishing a national reference laboratory, especially one with BSL-3 or -4 biocontainment facilities, requires a heavy investment of resources, a multisectoral approach, and commitments from multiple stakeholders. We make the case for donor organizations and recipient partners to develop a comprehensive laboratory operations roadmap that addresses factors such as mission and roles, engaging national and political support, securing financial support, defining stakeholder involvement, fostering partnerships, and building trust. Successful development occurred with projects in African countries and in Azerbaijan, where strong leadership and a clear management framework have been key to success. A clearly identified and agreed management framework facilitate identifying the responsibility for developing laboratory capabilities and support services, including biosafety and biosecurity, quality assurance, equipment maintenance, supply chain establishment, staff certification and training, retention of human resources, and sustainable operating revenue. These capabilities and support services pose rate-limiting yet necessary challenges. Laboratory capabilities depend on mission and role, as determined by all stakeholders, and demonstrate the need for relevant metrics to monitor the success of the laboratory, including support for internal and external audits. Our analysis concludes that alternative frameworks for success exist for developing and implementing capabilities at regional and national levels in limited resource areas. Thus, achieving a balance for standardizing practices between local procedures and accepted international standards is a prerequisite for integrating new facilities into a country's existing public health infrastructure and into the overall international scientific community.

Developing a lean culture in the laboratory.

PubMed

Napoles, Leyda; Quintana, Maria

2006-07-25

The Director of Pathology at Jackson Memorial Hospital was interested in improving the operational efficiencies of the department in order to enhance the department's level of service in conjunction with the expansion of the overall health system. The decision was made to implement proven Lean practices in the laboratory under the direction of a major consulting firm. This article details the scope of the initial project as well as the operating principles of Lean manufacturing practices as applied to the clinical laboratory. The goals of the project were to improve turnaround times of laboratory results, reduce inventory and supply costs, improve staff productivity, maximize workflow, and eliminate waste. Extensive data gathering and analysis guided the work process by highlighting the areas of highest opportunity. This systematic approach resulted in recommendations for the workflow and physical layout of the laboratory. It also included the introduction of "standard workflow" and "visual controls" as critical items that streamlined operational efficiencies. The authors provide actual photographs and schematics of the reorganization and improvements to the physical layout of the laboratory. In conclusion, this project resulted in decreased turnaround times and increased productivity, as well as significant savings in the overall laboratory operations.

Laboratory Directed Research and Development annual report, fiscal year 1997

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1998-03-01

The Department of Energy Order 413.2(a) establishes DOE`s policy and guidelines regarding Laboratory Directed Research and Development (LDRD) at its multiprogram laboratories. As described in 413.2, LDRD is research and development of a creative and innovative nature which is selected by the Laboratory Director or his or her designee, for the purpose of maintaining the scientific and technological vitality of the Laboratory and to respond to scientific and technological opportunities in conformance with the guidelines in this Order. DOE Order 413.2 requires that each laboratory submit an annual report on its LDRD activities to the cognizant Secretarial Officer through themore » appropriate Operations Office Manager. The report provided in this document represents Pacific Northwest National Laboratory`s LDRD report for FY 1997.« less

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kalemci, Emrah

This work summarizes the efforts in Turkey to build a laboratory capable of building and testing high energy astrophysics detectors that work in space. The EC FP6 ASTRONS project contributed strongly to these efforts, and as a result a fully operational laboratory at Sabanci University have been developed. In this laboratory we test and develop Si and CdZnTe based room temperature semiconductor strip detectors and develop detector and electronics system to be used as a payload on potential small Turkish satellites.

Architectures for mission control at the Jet Propulsion Laboratory

NASA Technical Reports Server (NTRS)

Davidson, Reger A.; Murphy, Susan C.

1992-01-01

JPL is currently converting to an innovative control center data system which is a distributed, open architecture for telemetry delivery and which is enabling advancement towards improved automation and operability, as well as new technology, in mission operations at JPL. The scope of mission control within mission operations is examined. The concepts of a mission control center and how operability can affect the design of a control center data system are discussed. Examples of JPL's mission control architecture, data system development, and prototype efforts at the JPL Operations Engineering Laboratory are provided. Strategies for the future of mission control architectures are outlined.

Overview of EPA Pesticide Laboratories and Methods

EPA Pesticide Factsheets

EPA operates two pesticide laboratories that provide a variety of technical services to the Agency, other federal and state agencies, tribal groups and other organizations.The labs develop methods and procedures.

Lumber drying and heat sterilization research at the U.S. Forest Products Laboratory

Treesearch

William T. Simpson

2002-01-01

The Forest Products Laboratory (FPL) has a long history of research and technology transfer in lumber drying. Many of the dry kiln schedules used in industry today were developed by the staff of the Laboratory, and for many years the Laboratory conducted a kiln drying short course for training dry kiln operators. The purpose of this report is to describe the Laboratory...

Water Quality & Pollutant Source Monitoring: Field and Laboratory Procedures. Training Manual.

ERIC Educational Resources Information Center

Office of Water Program Operations (EPA), Cincinnati, OH. National Training and Operational Technology Center.

This training manual presents material on techniques and instrumentation used to develop data in field monitoring programs and related laboratory operations concerned with water quality and pollution monitoring. Topics include: collection and handling of samples; bacteriological, biological, and chemical field and laboratory methods; field…

Results of Laboratory Tests of the Filtration Characteristics of Clay-Cement Concrete

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sol’skii, S. V., E-mail: solskiysv@vniig.ru; Lopatina, M. G., E-mail: LoptainaMG@vniig.ru; Legina, E. E.

Laboratory studies of the filtration characteristics of clay-cement concrete materials for constructing filtering diaphragms of earth dams by the method of secant piles are reported. Areas for further study aimed at improving the quality of construction, increasing operational safety, and developing a standards base for the design, construction, and operation of these systems are discussed.

Emergency preparedness for genetics centers, laboratories, and patients: the Southeast Region Genetics Collaborative strategic plan.

PubMed

Andersson, Hans C; Perry, William; Bowdish, Bruce; Floyd-Browning, Phaidra

2011-10-01

Emergencies occur unpredictably and interrupt routine genetic care. The events after hurricanes Katrina and Rita have led to the recognition that a coherent plan is necessary to ensure continuity of operations for genetic centers and laboratories, including newborn screening. No geographic region is protected from the effects of a variety of potential emergencies. Regional and national efforts have begun to address the need for such preparedness, but a plan for ensuring continuity of operations by creating an emergency preparedness plan must be developed for each genetic center and laboratory, with attention to the interests of patients. This article describes the first steps in development of an emergency preparedness plan for individual centers.

Concept Verification Test - Evaluation of Spacelab/Payload operation concepts

NASA Technical Reports Server (NTRS)

Mcbrayer, R. O.; Watters, H. H.

1977-01-01

The Concept Verification Test (CVT) procedure is used to study Spacelab operational concepts by conducting mission simulations in a General Purpose Laboratory (GPL) which represents a possible design of Spacelab. In conjunction with the laboratory a Mission Development Simulator, a Data Management System Simulator, a Spacelab Simulator, and Shuttle Interface Simulator have been designed. (The Spacelab Simulator is more functionally and physically representative of the Spacelab than the GPL.) Four simulations of Spacelab mission experimentation were performed, two involving several scientific disciplines, one involving life sciences, and the last involving material sciences. The purpose of the CVT project is to support the pre-design and development of payload carriers and payloads, and to coordinate hardware, software, and operational concepts of different developers and users.

18. VIEW OF THE GENERAL CHEMISTRY LAB. THE LABORATORY PROVIDED ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

18. VIEW OF THE GENERAL CHEMISTRY LAB. THE LABORATORY PROVIDED GENERAL ANALYTICAL AND STANDARDS CALIBRATION, AS WELL AS DEVELOPMENT OPERATIONS INCLUDING WASTE TECHNOLOGY DEVELOPMENT AND DEVELOPMENT AND TESTING OF MECHANICAL SYSTEMS FOR WEAPONS SYSTEMS. (4/4/66) - Rocky Flats Plant, General Manufacturing, Support, Records-Central Computing, Southern portion of Plant, Golden, Jefferson County, CO

Fiscal Year 2012 United States Air Force Agency Financial Report

DTIC Science & Technology

2012-01-01

Air Force Research Laboratory (AFRL) and Lawrence Livermore National Laboratory (LLNL) aggressively designed and tested an advanced warhead to...Reaper procurement & RPA capabilities, Light Attack Armed Reconnaissance buys, Joint Strike Fighter, satellites). Research , Development, Test and...Military Personnel Operations, Readiness & Support Procurement Research , Development, Test & Evaluation

[Assessment of learning activities using streaming video for laboratory practice education: aiming for development of E-learning system that promotes self-learning].

PubMed

Takeda, Naohito; Takeuchi, Isao; Haruna, Mitsumasa

2007-12-01

In order to develop an e-learning system that promotes self-learning, lectures and basic operations in laboratory practice of chemistry were recorded and edited on DVD media, consisting of 8 streaming videos as learning materials. Twenty-six students wanted to watch the DVD, and answered the following questions after they had watched it: "Do you think the video would serve to encourage you to study independently in the laboratory practice?" Almost all students (95%) approved of its usefulness, and more than 60% of them watched the videos repeatedly in order to acquire deeper knowledge and skill of the experimental operations. More than 60% answered that the demonstration-experiment should be continued in the laboratory practice, in spite of distribution of the DVD media.

Towards optimizing two-qubit operations in three-electron double quantum dots

NASA Astrophysics Data System (ADS)

Frees, Adam; Gamble, John King; Mehl, Sebastian; Friesen, Mark; Coppersmith, S. N.

The successful implementation of single-qubit gates in the quantum dot hybrid qubit motivates our interest in developing a high fidelity two-qubit gate protocol. Recently, extensive work has been done to characterize the theoretical limitations and advantages in performing two-qubit operations at an operation point located in the charge transition region. Additionally, there is evidence to support that single-qubit gate fidelities improve while operating in the so-called ``far-detuned'' region, away from the charge transition. Here we explore the possibility of performing two-qubit gates in this region, considering the challenges and the benefits that may present themselves while implementing such an operational paradigm. This work was supported in part by ARO (W911NF-12-0607) (W911NF-12-R-0012), NSF (PHY-1104660), ONR (N00014-15-1-0029). The authors gratefully acknowledge support from the Sandia National Laboratories Truman Fellowship Program, which is funded by the Laboratory Directed Research and Development (LDRD) Program. Sandia is a multi-program laboratory managed and operated by Sandia Corporation, a wholly owned subsidiary of Lockheed Martin Corporation, for the US Department of Energy's National Nuclear Security Administration under Contract No. DE-AC04-94AL85000.

DSP-Based Hands-On Laboratory Experiments for Photovoltaic Power Systems

ERIC Educational Resources Information Center

Muoka, Polycarp I.; Haque, Md. Enamul; Gargoom, Ameen; Negnetvitsky, Michael

2015-01-01

This paper presents a new photovoltaic (PV) power systems laboratory module that was developed to experimentally reinforce students' understanding of design principles, operation, and control of photovoltaic power conversion systems. The laboratory module is project-based and is designed to support a renewable energy course. By using MATLAB…

Summary of 1971 pattern recognition program development

NASA Technical Reports Server (NTRS)

Whitley, S. L.

1972-01-01

Eight areas related to pattern recognition analysis at the Earth Resources Laboratory are discussed: (1) background; (2) Earth Resources Laboratory goals; (3) software problems/limitations; (4) operational problems/limitations; (5) immediate future capabilities; (6) Earth Resources Laboratory data analysis system; (7) general program needs and recommendations; and (8) schedule and milestones.

76 FR 72216 - Occupational Exposure to Hazardous Chemicals in Laboratories Standard; Extension of the Office of...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-11-22

... by developing a written Chemical Hygiene Plan (CHP) that describes standard operating procedures for...] Occupational Exposure to Hazardous Chemicals in Laboratories Standard; Extension of the Office of Management... requirements specified in the Standard on Occupational Exposure to Hazardous Chemicals in Laboratories (29 CFR...

Undergraduate Laboratory Module on Skin Diffusion

ERIC Educational Resources Information Center

Norman, James J.; Andrews, Samantha N.; Prausnitz, Mark R.

2011-01-01

To introduce students to an application of chemical engineering directly related to human health, we developed an experiment for the unit operations laboratory at Georgia Tech examining diffusion across cadaver skin in the context of transdermal drug delivery. In this laboratory module, students prepare mouse skin samples, set up diffusion cells…

Laboratory Directed Research and Development Program FY 2006 Annual Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sjoreen, Terrence P

2007-04-01

The Oak Ridge National Laboratory (ORNL) Laboratory Directed Research and Development (LDRD) Program reports its status to the US Departmental of Energy (DOE) in March of each year. The program operates under the authority of DOE Order 413.2B, 'Laboratory Directed Research and Development' (April 19, 2006), which establishes DOE's requirements for the program while providing the Laboratory Director broad flexibility for program implementation. LDRD funds are obtained through a charge to all Laboratory programs. This report includes summaries all ORNL LDRD research activities supported during FY 2006. The associated FY 2006 ORNL LDRD Self-Assessment (ORNL/PPA-2007/2) provides financial data about themore » FY 2006 projects and an internal evaluation of the program's management process.« less

National Laboratory Planning: Developing Sustainable Biocontainment Laboratories in Limited Resource Areas

PubMed Central

Adams, Martin; Stamper, Paul D.; Dasgupta, Debanjana; Hewson, Roger; Buck, Charles D.; Richards, Allen L.; Hay, John

2016-01-01

Strategic laboratory planning in limited resource areas is essential for addressing global health security issues. Establishing a national reference laboratory, especially one with BSL-3 or -4 biocontainment facilities, requires a heavy investment of resources, a multisectoral approach, and commitments from multiple stakeholders. We make the case for donor organizations and recipient partners to develop a comprehensive laboratory operations roadmap that addresses factors such as mission and roles, engaging national and political support, securing financial support, defining stakeholder involvement, fostering partnerships, and building trust. Successful development occurred with projects in African countries and in Azerbaijan, where strong leadership and a clear management framework have been key to success. A clearly identified and agreed management framework facilitate identifying the responsibility for developing laboratory capabilities and support services, including biosafety and biosecurity, quality assurance, equipment maintenance, supply chain establishment, staff certification and training, retention of human resources, and sustainable operating revenue. These capabilities and support services pose rate-limiting yet necessary challenges. Laboratory capabilities depend on mission and role, as determined by all stakeholders, and demonstrate the need for relevant metrics to monitor the success of the laboratory, including support for internal and external audits. Our analysis concludes that alternative frameworks for success exist for developing and implementing capabilities at regional and national levels in limited resource areas. Thus, achieving a balance for standardizing practices between local procedures and accepted international standards is a prerequisite for integrating new facilities into a country's existing public health infrastructure and into the overall international scientific community. PMID:27559843

Laboratory Directed Research and Development FY-15 Annual Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pillai, Rekha Sukamar

The Laboratory Directed Research and Development (LDRD) Program at Idaho National Laboratory (INL) reports its status to the U.S. Department of Energy (DOE) by March of each year. The program operates under the authority of DOE Order 413.2B, “Laboratory Directed Research and Development” (April 19, 2006), which establishes DOE’s requirements for the program while providing the laboratory director broad flexibility for program implementation. LDRD funds are obtained through a charge to all INL programs. This report includes summaries of all INL LDRD research activities supported during Fiscal Year (FY) 2015.

Development opportunities for hospital clinical laboratory joint ventures.

PubMed

Van Riper, J A

1995-01-01

Regional health-care providers are being given the opportunity to collaborate in specialty health-care services. Collaboration to achieve superior economies of scale is very effective in the clinical laboratory industry. National laboratory chains are consolidating and enhancing their control of the industry to ensure their historic profitability. National companies have closed many laboratory facilities and have laid off substantial numbers of laboratory personnel. Health-care providers can regain control of their locally generated laboratory health-care dollars by joining forces with clinical laboratory joint ventures. Laboratorians can assist the healthcare providers in bringing laboratory services and employment back to the local community. New capital for operational development and laboratory information systems will help bring the laboratory to the point of care. The independent regional laboratory is focused on supporting the medical needs of the community. The profit generated from a laboratory joint venture is shared among local health-care providers, supporting their economic viability. The laboratories' ability to contribute to the development of profit-making ventures will provide capital for new laboratory development. All of the above will ensure the clinical laboratories' role in providing quality health care to our communities and employment opportunities for laboratory personnel.

Exploration Laboratory Analysis FY13

NASA Technical Reports Server (NTRS)

Krihak, Michael; Perusek, Gail P.; Fung, Paul P.; Shaw, Tianna, L.

2013-01-01

The Exploration Laboratory Analysis (ELA) project supports the Exploration Medical Capability (ExMC) risk, which is stated as the Risk of Inability to Adequately Treat an Ill or Injured Crew Member, and ExMC Gap 4.05: Lack of minimally invasive in-flight laboratory capabilities with limited consumables required for diagnosing identified Exploration Medical Conditions. To mitigate this risk, the availability of inflight laboratory analysis instrumentation has been identified as an essential capability in future exploration missions. Mission architecture poses constraints on equipment and procedures that will be available to treat evidence-based medical conditions according to the Space Medicine Exploration Medical Conditions List (SMEMCL), and to perform human research studies on the International Space Station (ISS) that are supported by the Human Health and Countermeasures (HHC) element. Since there are significant similarities in the research and medical operational requirements, ELA hardware development has emerged as a joint effort between ExMC and HHC. In 2012, four significant accomplishments were achieved towards the development of exploration laboratory analysis for medical diagnostics. These achievements included (i) the development of high priority analytes for research and medical operations, (ii) the development of Level 1 functional requirements and concept of operations documentation, (iii) the selection and head-to-head competition of in-flight laboratory analysis instrumentation, and (iv) the phase one completion of the Small Business Innovation Research (SBIR) projects under the topic Smart Phone Driven Blood-Based Diagnostics. To utilize resources efficiently, the associated documentation and advanced technologies were integrated into a single ELA plan that encompasses ExMC and HHC development efforts. The requirements and high priority analytes was used in the selection of the four in-flight laboratory analysis performers. Based upon the competition results, a down select process will be performed in the upcoming year. Looking ahead, this unified effort has positioned each element for an in-flight lab analysis demonstration of select diagnostics measurements in the 2015 timeframe.

Comprehensive facilities plan

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1997-09-01

The Ernest Orlando Lawrence Berkeley National Laboratory`s Comprehensive Facilities Plan (CFP) document provides analysis and policy guidance for the effective use and orderly future development of land and capital assets at the Berkeley Lab site. The CFP directly supports Berkeley Lab`s role as a multiprogram national laboratory operated by the University of California (UC) for the Department of Energy (DOE). The CFP is revised annually on Berkeley Lab`s Facilities Planning Website. Major revisions are consistent with DOE policy and review guidance. Facilities planing is motivated by the need to develop facilities for DOE programmatic needs; to maintain, replace and rehabilitatemore » existing obsolete facilities; to identify sites for anticipated programmatic growth; and to establish a planning framework in recognition of site amenities and the surrounding community. The CFP presents a concise expression of the policy for the future physical development of the Laboratory, based upon anticipated operational needs of research programs and the environmental setting. It is a product of the ongoing planning processes and is a dynamic information source.« less

Laboratory-Directed Research and Development 2016 Summary Annual Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pillai, Rekha Sukamar; Jacobson, Julie Ann

The Laboratory-Directed Research and Development (LDRD) Program at Idaho National Laboratory (INL) reports its status to the U.S. Department of Energy (DOE) by March of each year. The program operates under the authority of DOE Order 413.2C, “Laboratory Directed Research and Development” (April 19, 2006), which establishes DOE’s requirements for the program while providing the laboratory director broad flexibility for program implementation. LDRD funds are obtained through a charge to all INL programs. This report includes summaries of all INL LDRD research activities supported during Fiscal Year (FY) 2016. INL is the lead laboratory for the DOE Office of Nuclearmore » Energy (DOE-NE). The INL mission is to discover, demonstrate, and secure innovative nuclear energy solutions, other clean energy options, and critical infrastructure with a vision to change the world’s energy future and secure our critical infrastructure. Operating since 1949, INL is the nation’s leading research, development, and demonstration center for nuclear energy, including nuclear nonproliferation and physical and cyber-based protection of energy systems and critical infrastructure, as well as integrated energy systems research, development, demonstration, and deployment. INL has been managed and operated by Battelle Energy Alliance, LLC (a wholly owned company of Battelle) for DOE since 2005. Battelle Energy Alliance, LLC, is a partnership between Battelle, BWX Technologies, Inc., AECOM, the Electric Power Research Institute, the National University Consortium (Massachusetts Institute of Technology, Ohio State University, North Carolina State University, University of New Mexico, and Oregon State University), and the Idaho university collaborators (i.e., University of Idaho, Idaho State University, and Boise State University). Since its creation, INL’s research and development (R&D) portfolio has broadened with targeted programs supporting national missions to advance nuclear energy, enable clean energy deployment, and secure and modernize critical infrastructure. INL’s research, development, and demonstration capabilities, its resources, and its unique geography enable integration of scientific discovery, innovation, engineering, operations, and controls into complex large-scale testbeds for discovery, innovation, and demonstration of transformational clean energy and security concepts. These attributes strengthen INL’s leadership as a demonstration laboratory. As a national resource, INL also applies its capabilities and skills to the specific needs of other federal agencies and customers through DOE’s Strategic Partnership Program.« less

Integrating standard operating procedures and industry notebook standards to evaluate students in laboratory courses.

PubMed

Wallert, Mark A; Provost, Joseph J

2014-01-01

To enhance the preparedness of graduates from the Biochemistry and Biotechnology (BCBT) Major at Minnesota State University Moorhead for employment in the bioscience industry we have developed a new Industry certificate program. The BCBT Industry Certificate was developed to address specific skill sets that local, regional, and national industry experts identified as lacking in new B.S. and B.A. biochemistry graduates. The industry certificate addresses concerns related to working in a regulated industry such as Good Laboratory Practices, Good Manufacturing Practices, and working in a Quality System. In this article we specifically describe how we developed a validation course that uses Standard Operating Procedures to describe grading policy and laboratory notebook requirements in an effort to better prepare students to transition into industry careers. © 2013 by The International Union of Biochemistry and Molecular Biology.

Moving up the automation S-curve: The role of the laboratory automation support function in successful pharmaceutical R&D

PubMed Central

Maddux, Randy J.

1995-01-01

The political and economic climate that exists today is a challenging one for the pharmaceutical industry. To effectively compete in today's marketplace, companies must discover and develop truly innovative medicines. The R&D organizations within these companies are under increasing pressure to hold down costs while accomplishing this mission. In this environment of level head count and operating budgets, it is imperative that laboratory management uses resources in the most effective, efficient ways possible. Investment in laboratory automation is a proven tool for doing just that. This paper looks at the strategy and tactics behind the formation and evolution of a central automation/laboratory technology support function at the Glaxo Research Institute. Staffing of the function is explained, along with operating strategy and alignment with the scientific client base. Using the S-curve model of technological progress, both the realized and potential impact on successful R&D automation and laboratory technology development are assessed. PMID:18925012

Pacific Northwest National Laboratory institutional plan: FY 1996--2001

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1996-01-01

This report contains the operation and direction plan for the Pacific Northwest National Laboratory of the US Department of Energy. The topics of the plan include the laboratory mission and core competencies, the laboratory strategic plan; the laboratory initiatives in molecular sciences, microbial biotechnology, global environmental change, complex modeling of physical systems, advanced processing technology, energy technology development, and medical technologies and systems; core business areas, critical success factors, and resource projections.

Implementation of Good Clinical Laboratory Practice (GCLP) guidelines within the External Quality Assurance Program Oversight Laboratory (EQAPOL).

PubMed

Todd, Christopher A; Sanchez, Ana M; Garcia, Ambrosia; Denny, Thomas N; Sarzotti-Kelsoe, Marcella

2014-07-01

The EQAPOL contract was awarded to Duke University to develop and manage global proficiency testing programs for flow cytometry-, ELISpot-, and Luminex bead-based assays (cytokine analytes), as well as create a genetically diverse panel of HIV-1 viral cultures to be made available to National Institutes of Health (NIH) researchers. As a part of this contract, EQAPOL was required to operate under Good Clinical Laboratory Practices (GCLP) that are traditionally used for laboratories conducting endpoint assays for human clinical trials. EQAPOL adapted these guidelines to the management of proficiency testing programs while simultaneously incorporating aspects of ISO/IEC 17043 which are specifically designed for external proficiency management. Over the first two years of the contract, the EQAPOL Oversight Laboratories received training, developed standard operating procedures and quality management practices, implemented strict quality control procedures for equipment, reagents, and documentation, and received audits from the EQAPOL Central Quality Assurance Unit. GCLP programs, such as EQAPOL, strengthen a laboratory's ability to perform critical assays and provide quality assessments of future potential vaccines. © 2013.

Making the Nanoworld Accessible: Nanoscience Education Using Scanning Probe Methods

NASA Astrophysics Data System (ADS)

Knorr, Daniel; Killgore, Jason; Gray, Tomoko; Ginger, David; Wei, Joseph; Chen, Yeechi; Sarikaya, Mehmet; Fong, Hanson; Griffith, Tom; Overney, Rene

2008-03-01

A partnership between researchers and educators at the University of Washington, North Seattle Community College and two companies, Nanosurf, AG and nanoScience Instruments has been forged to develop a nationally replicable model of a sustainable and up-to-date undergraduate teaching laboratory of scanning probe microscopy (SPM) methods applied to nanoscience and nanotechnology. Within this partnership a new paradigm of operating and maintaining a SPM laboratory has been developed that provides a truly hands-on experience in a classroom laboratory setting with a small student to instrument ratio involving a variety of SPM techniques and topics. To date, we have run a first successful undergraduate laboratory workshop, where students were able to have extensive hands-on experience on five SPM modes of operation including: electrostatic force microscopy involving photovoltaic polymeric materials, tunneling microscopy and the determination of the workfunction, and nanolithography using the dip-pen method. http://depts.washington.edu/nanolab/NUE/UNIQUE/NUE/UNIQUE.htm

Space station operating system study

NASA Technical Reports Server (NTRS)

Horn, Albert E.; Harwell, Morris C.

1988-01-01

The current phase of the Space Station Operating System study is based on the analysis, evaluation, and comparison of the operating systems implemented on the computer systems and workstations in the software development laboratory. Primary emphasis has been placed on the DEC MicroVMS operating system as implemented on the MicroVax II computer, with comparative analysis of the SUN UNIX system on the SUN 3/260 workstation computer, and to a limited extent, the IBM PC/AT microcomputer running PC-DOS. Some benchmark development and testing was also done for the Motorola MC68010 (VM03 system) before the system was taken from the laboratory. These systems were studied with the objective of determining their capability to support Space Station software development requirements, specifically for multi-tasking and real-time applications. The methodology utilized consisted of development, execution, and analysis of benchmark programs and test software, and the experimentation and analysis of specific features of the system or compilers in the study.

The Ames Project (1942-1946)

ScienceCinema

None

2018-04-26

The Ames Laboratory was officially founded on May 17, 1947, following development of a process to purify uranium metal for the historic Manhattan Project. From 1942 to 1946, Ames Lab scientists produced over two-million pounds of uranium metal. A U.S. Department of Energy national research laboratory, the Ames Laboratory creates materials and energy solutions. Iowa State University operates Ames Laboratory under contract with the DOE.

Concept for a commercial space station laboratory

NASA Technical Reports Server (NTRS)

Wood, P. W.; Stark, P. M.

1984-01-01

The concept of a privately owned and operated fee-for-service laboratory as an element of a civil manned space station, envisioned as the venture of a group of private investors and an experienced laboratory operator to be undertaken with the cooperation of NASA is discussed. This group would acquire, outfit, activate, and operate the labortory on a fee-for-service basis, providing laboratory services to commercial firms, universities, and government agencies, including NASA. This concept was developed to identify, stimulate, and assist potential commercial users of a manned space station. A number of the issues which would be related to the concept, including the terms under which NASA might consider permitting private ownership and operation of a major space station component, the policies with respect to international participation in the construction and use of the space station, the basis for charging users for services received from the space station, and the types of support that NASA might be willing to provide to assist private industry in carrying out such a venture are discussed.

Assessment of Sensor Technologies for Advanced Reactors

DOE Office of Scientific and Technical Information (OSTI.GOV)

Korsah, Kofi; Ramuhalli, Pradeep; Vlim, R.

2016-10-01

Sensors and measurement technologies provide information on processes, support operations and provide indications of component health. They are therefore crucial to plant operations and to commercialization of advanced reactors (AdvRx). This report, developed by a three-laboratory team consisting of Argonne National Laboratory (ANL), Oak Ridge National Laboratory (ORNL) and Pacific Northwest National Laboratory (PNNL), provides an assessment of sensor technologies and a determination of measurement needs for AdvRx. It provides the technical basis for identifying and prioritizing research targets within the instrumentation and control (I&C) Technology Area under the Department of Energy’s (DOE’s) Advanced Reactor Technology (ART) program and contributesmore » to the design and implementation of AdvRx concepts.« less

US Army Medical Bioengineering Research and Development Laboratory Annual Progress Report for FY 84. Volume 1

DTIC Science & Technology

1984-10-01

develop pollution abatement procedures for Army munition plants and military installations.n, t ftr Laboratory is also actively engaged in the...FACILITIES The physical plant provides over 100,000 square feet for research, development, testing, and administrative activities . Space is...protection of industrial workers and thq surrounding community at Army-controlled, industry-operated munition plants . G Environmental Quality program

Development of Individually Addressable Micro-Mirror-Arrays for Space Applications

NASA Technical Reports Server (NTRS)

Dutta, Sanghamitra B.; Ewin, Audrey J.; Jhabvala, Murzy; Kotecki, Carl A.; Kuhn, Jonathan L.; Mott, D. Brent

2000-01-01

We have been developing a 32 x 32 prototype array of individually addressable Micro-Mirrors capable of operating at cryogenic temperature for Earth and Space Science applications. Micro-Mirror-Array technology has the potential to revolutionize imaging and spectroscopy systems for NASA's missions of the 21st century. They can be used as programmable slits for the Next Generation Space Telescope, as smart sensors for a steerable spectrometer, as neutral density filters for bright scene attenuation etc. The, entire fabrication process is carried out in the Detector Development Laboratory at NASA, GSFC. The fabrication process is low temperature compatible and involves integration of conventional CMOS technology and surface micro-machining used in MEMS. Aluminum is used as the mirror material and is built on a silicon substrate containing the CMOS address circuit. The mirrors are 100 microns x l00 microns in area and deflect by +/- 10 deg induced by electrostatic actuation between two parallel plate capacitors. A pair of thin aluminum torsion straps allow the mirrors to tilt. Finite-element-analysis and closed form solutions using electrostatic and mechanical torque for mirror operation were developed and the results were compared with laboratory performance. The results agree well both at room temperature and at cryogenic temperature. The development demonstrates the first cryogenic operation of two-dimensional Micro-Mirrors with bi-state operation. Larger arrays will be developed meeting requirements for different science applications. Theoretical analysis, fabrication process, laboratory test results and different science applications will be described in detail.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Green, D.W.; Boparai, A.S.; Bowers, D.L.

This report summarizes the activities of the Analytical Chemistry Laboratory (ACL) at Argonne National Laboratory (ANL) for Fiscal Year (FY) 2000 (October 1999 through September 2000). This annual progress report, which is the seventeenth in this series for the ACL, describes effort on continuing projects, work on new projects, and contributions of the ACL staff to various programs at ANL. The ACL operates within the ANL system as a full-cost-recovery service center, but it has a mission that includes a complementary research and development component: The Analytical Chemistry Laboratory will provide high-quality, cost-effective chemical analysis and related technical support tomore » solve research problems of our clients--Argonne National Laboratory, the Department of Energy, and others--and will conduct world-class research and development in analytical chemistry and its applications. The ACL handles a wide range of analytical problems that reflects the diversity of research and development (R&D) work at ANL. Some routine or standard analyses are done, but the ACL operates more typically in a problem-solving mode in which development of methods is required or adaptation of techniques is needed to obtain useful analytical data. The ACL works with clients and commercial laboratories if a large number of routine analyses are required. Much of the support work done by the ACL is very similar to applied analytical chemistry research work.« less

Dual benefit robotics programs at Sandia National Laboratories

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jones, A.T.

Sandia National Laboratories has one of the largest integrated robotics laboratories in the United States. Projects include research, development, and application of one-of-a-kind systems, primarily for the Department of Energy (DOE) complex. This work has been underway for more than 10 years. It began with on-site activities that required remote operation, such as reactor and nuclear waste handling. Special purpose robot systems were developed using existing commercial manipulators and fixtures and programs designed in-house. These systems were used in applications such as servicing the Sandia pulsed reactor and inspecting remote roof bolts in an underground radioactive waste disposal facility. Inmore » the beginning, robotics was a small effort, but with increasing attention to the use of robots for hazardous operations, efforts now involve a staff of more than 100 people working in a broad robotics research, development, and applications program that has access to more than 30 robotics systems.« less

Optical fiber cable and wiring techniques for fiber to the home (FTTH)

NASA Astrophysics Data System (ADS)

Takai, Hirofumi; Yamauchi, Osamu

2009-08-01

NTT group's new medium-term management strategy calls for 20 million optical subscribers by 2010, and NTT Laboratories is pushing forward to meet this goal. Before that date, an efficient optical access network must be constructed, and afterwards, when the era of mass optical communications finally arrives, the facilities and equipment supporting the network will have to be effectively operated and maintained. At NTT Access Network Service Systems Laboratories, we are developing various technologies to correspond to the massive deployment of optical broadband services. We are also developing various new technologies for efficiently operating optical access network systems that will continue to expand in the future, and to supply our customers with good services. This paper provides an overview of the new optical access network system technologies that are being developed at NTT Access Network Service Systems Laboratories to address these issues.

Sweep-twist adaptive rotor blade : final project report.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ashwill, Thomas D.

2010-02-01

Knight & Carver was contracted by Sandia National Laboratories to develop a Sweep Twist Adaptive Rotor (STAR) blade that reduced operating loads, thereby allowing a larger, more productive rotor. The blade design used outer blade sweep to create twist coupling without angled fiber. Knight & Carver successfully designed, fabricated, tested and evaluated STAR prototype blades. Through laboratory and field tests, Knight & Carver showed the STAR blade met the engineering design criteria and economic goals for the program. A STAR prototype was successfully tested in Tehachapi during 2008 and a large data set was collected to support engineering and commercialmore » development of the technology. This report documents the methodology used to develop the STAR blade design and reviews the approach used for laboratory and field testing. The effort demonstrated that STAR technology can provide significantly greater energy capture without higher operating loads on the turbine.« less

Leading Antibacterial Laboratory Research by Integrating Conventional and Innovative Approaches: The Laboratory Center of the Antibacterial Resistance Leadership Group.

PubMed

Manca, Claudia; Hill, Carol; Hujer, Andrea M; Patel, Robin; Evans, Scott R; Bonomo, Robert A; Kreiswirth, Barry N

2017-03-15

The Antibacterial Resistance Leadership Group (ARLG) Laboratory Center (LC) leads the evaluation, development, and implementation of laboratory-based research by providing scientific leadership and supporting standard/specialized laboratory services. The LC has developed a physical biorepository and a virtual biorepository. The physical biorepository contains bacterial isolates from ARLG-funded studies located in a centralized laboratory and they are available to ARLG investigators. The Web-based virtual biorepository strain catalogue includes well-characterized gram-positive and gram-negative bacterial strains published by ARLG investigators. The LC, in collaboration with the ARLG Leadership and Operations Center, developed procedures for review and approval of strain requests, guidance during the selection process, and for shipping strains from the distributing laboratories to the requesting investigators. ARLG strains and scientific and/or technical guidance have been provided to basic research laboratories and diagnostic companies for research and development, facilitating collaboration between diagnostic companies and the ARLG Master Protocol for Evaluating Multiple Infection Diagnostics (MASTERMIND) initiative for evaluation of multiple diagnostic devices from a single patient sampling event. In addition, the LC has completed several laboratory-based studies designed to help evaluate new rapid molecular diagnostics by developing, testing, and applying a MASTERMIND approach using purified bacterial strains. In collaboration with the ARLG's Statistical and Data Management Center (SDMC), the LC has developed novel analytical strategies that integrate microbiologic and genetic data for improved and accurate identification of antimicrobial resistance. These novel approaches will aid in the design of future ARLG studies and help correlate pathogenic markers with clinical outcomes. The LC's accomplishments are the result of a successful collaboration with the ARLG's Leadership and Operations Center, Diagnostics and Devices Committee, and SDMC. This interactive approach has been pivotal for the success of LC projects. © The Author 2017. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: journals.permissions@oup.com.

Development, Testing and Operation of a Large Suspended Ocean Measurement Structure for Deep-Ocean Use

DTIC Science & Technology

1992-05-01

and systems for developing , testing, and operating the system. A new, lightweight cable de- used this evolving technology base in the ensuing years...Funding Numbers. Development , Testing, and Operation of a Large Suspended Ocean Contrac Measurement Structure for Deep-Ocean Use Program Element No...Research L.aboratory Report Number. Ocean Acoutics and Technology Directorate PR 91:132:253 Stennis Space Center, MS 39529-5004 9. Sponsoring

IDC Re-Engineering Phase 3 Development Plan.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Harris, James M.; Burns, John F.; Pollock, David L.

2017-01-01

Sandia National Laboratories has prepared a project development plan that proposes how the parties interested in the IDC Re-Engineering system will coordinate its development, testing and transition to operations.

Annotated Bibliography of USAARL Technical and Letter Reports. Volume 2. October 1988 - April 1991

DTIC Science & Technology

1991-05-01

G. Lilienthal, Robert S. Kennedy, Jennifer E. Fowlkes, and Dennis R. Baltzley. As technelogy has been developed to provide improved visual and motion...Gower, Jr., and Jennifer Fowlkes. The U.S. Army Aeromedical Research Laboratory conducted field studies of operational flight simulators to assess the...Daniel W. Gower, Jr., and Jennifer Fowlkes. The U.S. Army Aeromedical Research Laboratory conducted field studies of operational flight simulators to

NASA Glenn Research Center's Fuel Cell Stack, Ancillary and System Test and Development Laboratory

NASA Technical Reports Server (NTRS)

Loyselle, Patricia L.; Prokopius, Kevin P.; Becks, Larry A.; Burger, Thomas H.; Dick, Joseph F.; Rodriguez, George; Bremenour, Frank; Long, Zedock

2011-01-01

At the NASA Glenn Research Center, a fully operational fuel cell test and evaluation laboratory is available which is capable of evaluating fuel cell components and systems for future NASA missions. Components and subsystems of various types can be operated and monitored under a variety of conditions utilizing different reactants. This fuel cell facility can test the effectiveness of various component and system designs to meet NASA's needs.

Contingency Operations Support to NASA Johnson Space Center Medical Operations Division

NASA Technical Reports Server (NTRS)

Stepaniak, Philip; Patlach, Bob; Swann, Mark; Adams, Adrien

2005-01-01

The Wyle Laboratories Contingency Operations Group provides support to the NASA Johnson Space Center (JSC) Medical Operations Division in the event of a space flight vehicle accident or JSC mishap. Support includes development of Emergency Medical System (EMS) requirements, procedures, training briefings and real-time support of mishap investigations. The Contingency Operations Group is compliant with NASA documentation that provides guidance in these areas and maintains contact with the United States Department of Defense (DOD) to remain current on military plans to support NASA. The contingency group also participates in Space Operations Medical Support Training Courses (SOMSTC) and represents the NASA JSC Medical Operations Division at contingency exercises conducted worldwide by the DOD or NASA. The events of September 11, 2001 have changed how this country prepares and protects itself from possible terrorist attacks on high-profile targets. As a result, JSC is now considered a high-profile target and thus, must prepare for and develop a response to a Weapons of Mass Destruction (WMD) incident. The Wyle Laboratories Contingency Operations Group supports this plan, specifically the medical response, by providing expertise and manpower.

A distributed data acquisition software scheme for the Laboratory Telerobotic Manipulator

DOE Office of Scientific and Technical Information (OSTI.GOV)

Butler, P.L.; Glassell, R.L.; Rowe, J.C.

1990-01-01

A custom software architecture was developed for use in the Laboratory Telerobotic Manipulator (LTM) to provide support for the distributed data acquisition electronics. This architecture was designed to provide a comprehensive development environment that proved to be useful for both hardware and software debugging. This paper describes the development environment and the operational characteristics of the real-time data acquisition software. 8 refs., 5 figs.

Selected Lessons Learned over the ISS Design, Development, Assembly, and Operations: Applicability to International Cooperation for Standardization

NASA Technical Reports Server (NTRS)

Hirsch, David B.

2010-01-01

This slide presentation reviews some of the lessons learned in the sphere of international cooperation during the development, assembly and operation of the International Space Station. From the begining all Partners shared a common objective to build, operate and utilize a crewed laboratory in low orbit as an international partnership. The importance of standards is emphasized.

Point-of-care diagnostics: extending the laboratory network to reach the last mile.

PubMed

Drain, Paul K; Rousseau, Christine

2017-03-01

More point-of-care (POC) diagnostic tests are becoming available for HIV diagnosis and treatment in resource-limited settings. These novel technologies have the potential to foster decentralized HIV care and treatment for the benefit of clinical laboratories, HIV clinics, and HIV-infected patients. There continue to be many business, technological, and operational challenges that limit product development and regulatory approval, which limits products available for the required operational and cost-effectiveness studies and delays policy adoption and implementation. Although the rapid HIV diagnostic test has been widely successful, the pathways for POC CD4 cell count and HIV viral load assay analyzers have been more challenging. We describe significant hurdles for product development, approval, and implementation, which include the business case, technical development, clinical impact, and integrating laboratory and clinical networks. The objective of this review is to highlight the obstacles for developing and implementing appropriate strategies for POC HIV testing assays to improve the clinical services for HIV-infected patients in resource-limited settings.

Report on the Progress of Weld Development of Irradiated Materials at the Oak Ridge National Laboratory

DOE Office of Scientific and Technical Information (OSTI.GOV)

Feng, Zhili; Miller, Roger G.; Chen, Jian

This report summarizes recent welding activities on irradiated alloys in the advanced welding facility at the Radiochemical Engineering Development Center of Oak Ridge National Laboratory and the development of post-weld characterization capabilities and procedures that will be critical for assessing the ability of the advanced welding processes housed within the facility to make successful repairs on irradiated alloys. This facility and its capabilities were developed jointly by the U.S. Department of Energy, Office of Nuclear Energy, Light Water Reactor Sustainability Program and the Electric Power Research Institute, Long Term Operations Program (and the Welding and Repair Technology Center), with additionalmore » support from Oak Ridge National Laboratory. The significant, on-going effort to weld irradiated alloys with high Helium concentrations and comprehensively analyze the results will eventually yield validated repair techniques and guidelines for use by the nuclear industry in extending the operational lifetimes of nuclear power plants.« less

ORNLs Laboratory Directed Research and Development Program FY 2009 Annual Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

None, None

2010-03-01

The Laboratory Directed Research and Development (LDRD) program at Oak Ridge National Laboratory (ORNL) reports its status to the U.S. Department of Energy (DOE) in March of each year. The program operates under the authority of DOE Order 413.2B, “Laboratory Directed Research and Development” (April 19, 2006), which establishes DOE’s requirements for the program while providing the Laboratory Director broad flexibility for program implementation. LDRD funds are obtained through a charge to all Laboratory programs. This report includes summaries all ORNL LDRD research activities supported during FY 2009. The associated FY 2009 ORNL LDRD Self-Assessment (ORNL/PPA-2010/2) provides financial data andmore » an internal evaluation of the program’s management process.« less

ORNLs Laboratory Directed Research and Development Program FY 2013 Annual Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

None, None

2014-03-01

The Laboratory Directed Research and Development (LDRD) program at Oak Ridge National Laboratory (ORNL) reports its status to the US Department of Energy (DOE) in March of each year. The program operates under the authority of DOE Order 413.2B, “Laboratory Directed Research and Development” (April 19, 2006), which establishes DOE’s requirements for the program while providing the Laboratory Director broad flexibility for program implementation. LDRD funds are obtained through a charge to all Laboratory programs. This report includes summaries of all ORNL LDRD research activities supported during FY 2013. The associated FY 2013 ORNL LDRD Self-Assessment (ORNL/PPA-2014/2) provides financial datamore » and an internal evaluation of the program’s management process.« less

ORNLs Laboratory Directed Research and Development Program FY 2008 Annual Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

None, None

2009-03-01

The Oak Ridge National Laboratory (ORNL) Laboratory Directed Research and Development (LDRD) Program reports its status to the U.S. Department of Energy (DOE) in March of each year. The program operates under the authority of DOE Order 413.2B, “Laboratory Directed Research and Development” (April 19, 2006), which establishes DOE’s requirements for the program while providing the Laboratory Director broad flexibility for program implementation. LDRD funds are obtained through a charge to all Laboratory programs. This report includes summaries all ORNL LDRD research activities supported during FY 2008. The associated FY 2008 ORNL LDRD Self-Assessment (ORNL/PPA-2008/2) provides financial data and anmore » internal evaluation of the program’s management process.« less

ORNLs Laboratory Directed Research and Development Program FY 2012 Annual Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

None, None

2013-03-01

The Laboratory Directed Research and Development (LDRD) program at Oak Ridge National Laboratory (ORNL) reports its status to the US Department of Energy (DOE) in March of each year. The program operates under the authority of DOE Order 413.2B, “Laboratory Directed Research and Development” (April 19, 2006), which establishes DOE’s requirements for the program while providing the Laboratory Director broad flexibility for program implementation. LDRD funds are obtained through a charge to all Laboratory programs. This report includes summaries of all ORNL LDRD research activities supported during FY 2012. The associated FY 2012 ORNL LDRD Self-Assessment (ORNL/PPA-2012/2) provides financial datamore » and an internal evaluation of the program’s management process.« less

Lunar exploration rover program developments

NASA Technical Reports Server (NTRS)

Klarer, P. R.

1994-01-01

The Robotic All Terrain Lunar Exploration Rover (RATLER) design concept began at Sandia National Laboratories in late 1991 with a series of small, proof-of-principle, working scale models. The models proved the viability of the concept for high mobility through mechanical simplicity, and eventually received internal funding at Sandia National Laboratories for full scale, proof-of-concept prototype development. Whereas the proof-of-principle models demonstrated the mechanical design's capabilities for mobility, the full scale proof-of-concept design currently under development is intended to support field operations for experiments in telerobotics, autonomous robotic operations, telerobotic field geology, and advanced man-machine interface concepts. The development program's current status is described, including an outline of the program's work over the past year, recent accomplishments, and plans for follow-on development work.

A Strategy for an Enterprise-Wide Data Management Capability at the Jet Propulsion Laboratory

NASA Technical Reports Server (NTRS)

Fuhrman, D.

2000-01-01

The Jet Propulsion Laboratory (JPL) is a Federally Research and Development Center (FFRDC) operated by the California Institute of Technology that is engaged in the quest for knowledge about the solar system, the universe, and the Earth.

Cryogenics Testbed Laboratory Flange Baseline Configuration

NASA Technical Reports Server (NTRS)

Acuna, Marie Lei Ysabel D.

2013-01-01

As an intern at Kennedy Space Center (KSC), I was involved in research for the Fluids and Propulsion Division of the NASA Engineering (NE) Directorate. I was immersed in the Integrated Ground Operations Demonstration Units (IGODU) project for the majority of my time at KSC, primarily with the Ground Operations Demonstration Unit Liquid Oxygen (GODU L02) branch of IGODU. This project was established to develop advancements in cryogenic systems as a part of KSC's Advanced Exploration Systems (AES) program. The vision of AES is to develop new approaches for human exploration, and operations in and beyond low Earth orbit. Advanced cryogenic systems are crucial to minimize the consumable losses of cryogenic propellants, develop higher performance launch vehicles, and decrease operations cost for future launch programs. During my internship, I conducted a flange torque tracking study that established a baseline configuration for the flanges in the Simulated Propellant Loading System (SPLS) at the KSC Cryogenics Test Laboratory (CTL) - the testing environment for GODU L02.

Payload crew interface design criteria and techniques. Task 1: Inflight operations and training for payloads. [space shuttles

NASA Technical Reports Server (NTRS)

Carmean, W. D.; Hitz, F. R.

1976-01-01

Guidelines are developed for use in control and display panel design for payload operations performed on the aft flight deck of the orbiter. Preliminary payload procedures are defined. Crew operational concepts are developed. Payloads selected for operational simulations were the shuttle UV optical telescope (SUOT), the deep sky UV survey telescope (DUST), and the shuttle UV stellar spectrograph (SUSS). The advanced technology laboratory payload consisting of 11 experiments was selected for a detailed evaluation because of the availability of operational data and its operational complexity.

EVA Development and Verification Testing at NASA's Neutral Buoyancy Laboratory

NASA Technical Reports Server (NTRS)

Jairala, Juniper C.; Durkin, Robert; Marak, Ralph J.; Sipila, Stepahnie A.; Ney, Zane A.; Parazynski, Scott E.; Thomason, Arthur H.

2012-01-01

As an early step in the preparation for future Extravehicular Activities (EVAs), astronauts perform neutral buoyancy testing to develop and verify EVA hardware and operations. Neutral buoyancy demonstrations at NASA Johnson Space Center's Sonny Carter Training Facility to date have primarily evaluated assembly and maintenance tasks associated with several elements of the International Space Station (ISS). With the retirement of the Shuttle, completion of ISS assembly, and introduction of commercial players for human transportation to space, evaluations at the Neutral Buoyancy Laboratory (NBL) will take on a new focus. Test objectives are selected for their criticality, lack of previous testing, or design changes that justify retesting. Assembly tasks investigated are performed using procedures developed by the flight hardware providers and the Mission Operations Directorate (MOD). Orbital Replacement Unit (ORU) maintenance tasks are performed using a more systematic set of procedures, EVA Concept of Operations for the International Space Station (JSC-33408), also developed by the MOD. This paper describes the requirements and process for performing a neutral buoyancy test, including typical hardware and support equipment requirements, personnel and administrative resource requirements, examples of ISS systems and operations that are evaluated, and typical operational objectives that are evaluated.

Development of an advanced anaerobic digester design and a kinetic model for biogasification of water hyacinth/sludge blends

DOE Office of Scientific and Technical Information (OSTI.GOV)

Srivastava, V.; Fannin, K.F.; Biljetina, R.

1986-07-01

The Institute of Gas Technology (IGT) conducted a comprehensive laboratory-scale research program to develop and optimize the anaerobic digestion process for producing methane from water hyacinth and sludge blends. This study focused on digester design and operating techniques, which gave improved methane yields and production rates over those observed using conventional digesters. The final digester concept and the operating experience was utilized to design and operate a large-scale experimentla test unit (ETU) at Walt Disney World, Florida. This paper describes the novel digester design, operating techniques, and the results obtained in the laboratory. The paper also discusses a kinetic modelmore » which predicts methane yield, methane production rate, and digester effluent solids as a function of retention time. This model was successfully utilized to predict the performance of the ETU. 15 refs., 6 figs., 6 tabs.« less

Department of Defense In-House RDT&E Activities

DTIC Science & Technology

1986-10-30

Research Management, Air Force IResearch, Army Research . Navy Researche Research 19 ABSTRACT (Continue on reverse if necessary and identify by block...Aeromedical Research Laboratory ........................ 1 Air Defense Artillery Board ............................ 2 Airborne & Special Operations...NAVY Aerospace Medical Research Laboratory .................. 55 Air Development Center ................................. 56 Air Propulsion

Reflections on some early events related to behavior analysis of child development

PubMed Central

Bijou, Sidney W.

1996-01-01

A series of events related to the early application of behavioral principles to child behavior and development is described. The events began in the 1930s at Columbia University with a solicited letter from John B. Watson suggesting a master's degree thesis problem, and continued through the 1950s and 1960s at the University of Washington. Specifically, these happenings resulted in (a) research demonstrating that Skinner's laboratory method for studying nonhuman organisms could be profitably applied to the laboratory study of young normal children; (b) a demonstration that by successive approximations, a normal child can be operantly conditioned to respond to an arbitrary situation; (c) research showing that the effects of simple schedules of reinforcement obtained with nonhuman organisms could be duplicated in young normal and retarded children; (d) the demonstration that Skinner's operant laboratory method could be adapted to study young children in field situations; (e) research showing that operant principles can be successfully applied to the treatment of a young autistic boy with a serious visual handicap; (f) laboratory studies showing that mothers can be trained to treat their own young children who have behavior problems; (g) an in-home study demonstrating that a mother can treat her own child who has behavior problems; (h) a demonstration that operant principles can be applied effectively to teaching reading, writing, and arithmetic to children with retardation; and (i) publication of a book, Child Development: A Systematic and Empirical Theory, in collaboration with Donald M. Baer, by Prentice Hall in their Century Psychological Series. PMID:22478239

Development of a wideband pulse quaternary modulation system. [for an operational 400 Mbps baseband laser communication system

NASA Technical Reports Server (NTRS)

Federhofer, J. A.

1974-01-01

Laboratory data verifying the pulse quaternary modulation (PQM) theoretical predictions is presented. The first laboratory PQM laser communication system was successfully fabricated, integrated, tested and demonstrated. System bit error rate tests were performed and, in general, indicated approximately a 2 db degradation from the theoretically predicted results. These tests indicated that no gross errors were made in the initial theoretical analysis of PQM. The relative ease with which the entire PQM laboratory system was integrated and tested indicates that PQM is a viable candidate modulation scheme for an operational 400 Mbps baseband laser communication system.

Dynamics of Quantum Causal Structures

NASA Astrophysics Data System (ADS)

Castro-Ruiz, Esteban; Giacomini, Flaminia; Brukner, Časlav

2018-01-01

It was recently suggested that causal structures are both dynamical, because of general relativity, and indefinite, because of quantum theory. The process matrix formalism furnishes a framework for quantum mechanics on indefinite causal structures, where the order between operations of local laboratories is not definite (e.g., one cannot say whether operation in laboratory A occurs before or after operation in laboratory B ). Here, we develop a framework for "dynamics of causal structures," i.e., for transformations of process matrices into process matrices. We show that, under continuous and reversible transformations, the causal order between operations is always preserved. However, the causal order between a subset of operations can be changed under continuous yet nonreversible transformations. An explicit example is that of the quantum switch, where a party in the past affects the causal order of operations of future parties, leading to a transition from a channel from A to B , via superposition of causal orders, to a channel from B to A . We generalize our framework to construct a hierarchy of quantum maps based on transformations of process matrices and transformations thereof.

Six component robotic force-torque sensor

NASA Technical Reports Server (NTRS)

Grahn, Allen R.; Hutchings, Brad L.; Johnston, David R.; Parsons, David C.; Wyatt, Roland F.

1987-01-01

The results of a two-phase contract studying the feasibility of a miniaturized six component force-torque sensor and development of a working laboratory system were described. The principle of operation is based upon using ultrasonic pulse-echo ranging to determine the position of ultrasonic reflectors attached to a metal or ceramic cover plate. Because of the small size of the sensor, this technology may have application in robotics, to sense forces and torques at the finger tip of a robotic end effector. Descriptions are included of laboratory experiments evaluating materials and techniques for sensor fabrication and of the development of support electronics for data acquisition, computer interface, and operator display.

Real-Time Rocket/Vehicle System Integrated Health Management Laboratory For Development and Testing of Health Monitoring/Management Systems

NASA Technical Reports Server (NTRS)

Aguilar, R.

2006-01-01

Pratt & Whitney Rocketdyne has developed a real-time engine/vehicle system integrated health management laboratory, or testbed, for developing and testing health management system concepts. This laboratory simulates components of an integrated system such as the rocket engine, rocket engine controller, vehicle or test controller, as well as a health management computer on separate general purpose computers. These general purpose computers can be replaced with more realistic components such as actual electronic controllers and valve actuators for hardware-in-the-loop simulation. Various engine configurations and propellant combinations are available. Fault or failure insertion capability on-the-fly using direct memory insertion from a user console is used to test system detection and response. The laboratory is currently capable of simulating the flow-path of a single rocket engine but work is underway to include structural and multiengine simulation capability as well as a dedicated data acquisition system. The ultimate goal is to simulate as accurately and realistically as possible the environment in which the health management system will operate including noise, dynamic response of the engine/engine controller, sensor time delays, and asynchronous operation of the various components. The rationale for the laboratory is also discussed including limited alternatives for demonstrating the effectiveness and safety of a flight system.

Cost efficient operations for Discovery class missions

NASA Technical Reports Server (NTRS)

Cameron, G. E.; Landshof, J. A.; Whitworth, G. W.

1994-01-01

The Near Earth Asteroid Rendezvous (NEAR) program at The Johns Hopkins University Applied Physics Laboratory is scheduled to launch the first spacecraft in NASA's Discovery program. The Discovery program is to promote low cost spacecraft design, development, and mission operations for planetary space missions. The authors describe the NEAR mission and discuss the design and development of the NEAR Mission Operations System and the NEAR Ground System with an emphasis on those aspects of the design that are conducive to low-cost operations.

Configurable technology development for reusable control and monitor ground systems

NASA Technical Reports Server (NTRS)

Uhrlaub, David R.

1994-01-01

The control monitor unit (CMU) uses configurable software technology for real-time mission command and control, telemetry processing, simulation, data acquisition, data archiving, and ground operations automation. The base technology is currently planned for the following control and monitor systems: portable Space Station checkout systems; ecological life support systems; Space Station logistics carrier system; and the ground system of the Delta Clipper (SX-2) in the Single-Stage Rocket Technology program. The CMU makes extensive use of commercial technology to increase capability and reduce development and life-cycle costs. The concepts and technology are being developed by McDonnell Douglas Space and Defense Systems for the Real-Time Systems Laboratory at NASA's Kennedy Space Center under the Payload Ground Operations Contract. A second function of the Real-Time Systems Laboratory is development and utilization of advanced software development practices.

A finite difference model used to predict the consolidation of a ceramic waste form produced from the electrometallurgical treatment of spent nuclear fuel.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bateman, K. J.; Capson, D. D.

2004-03-29

Argonne National Laboratory (ANL) has developed a process to immobilize waste salt containing fission products, uranium, and transuranic elements as chlorides in a glass-bonded ceramic waste form. This salt was generated in the electrorefining operation used in the electrometallurgical treatment of spent Experimental Breeder Reactor-II (EBR-II) fuel. The ceramic waste process culminates with an elevated temperature operation. The processing conditions used by the furnace, for demonstration scale and production scale operations, are to be developed at Argonne National Laboratory-West (ANL-West). To assist in selecting the processing conditions of the furnace and to reduce the number of costly experiments, a finitemore » difference model was developed to predict the consolidation of the ceramic waste. The model accurately predicted the heating as well as the bulk density of the ceramic waste form. The methodology used to develop the computer model and a comparison of the analysis to experimental data is presented.« less

Performance of the Colorado wind-profiling network, part 1.5A

NASA Technical Reports Server (NTRS)

Strauch, R. G.; Earnshaw, K. B.; Merritt, D. A.; Moran, K. P.; Vandekamp, D. W.

1984-01-01

The Wave Propagation Laboratory (WPL) has operated a network of radar wind Profilers in Colorado for about 1 year. The network consists of four VHF (50-MHz) radars and a UHF (915-MHz) radar. The Platteville VHF radar was developed by the Aeronomy Laboratory (AL) and has been operated jointly by WPL and AL for several years. The other radars were installed between February and May 1983. Experiences with these radars and some general aspects of tropospheric wind measurements with Doppler radar are discussed.

KSC-2012-6221

NASA Image and Video Library

2012-11-08

CAPE CANAVERAL, Fla. -- Inside the Applied Physics Laboratory in the Operations and Checkout Building at NASA’s Kennedy Space Center in Florida, lead researcher Dr. Bob Youngquist demonstrates a technology developed for the Space Shuttle Program to a group of Society of Physics students. About 800 graduate and undergraduate physics students toured Kennedy facilities. A group of about 40 students toured laboratories in the Operations and Checkout Building and the EDL during their visit. The physics students were in Orlando for the 2012 Quadrennial Physics Congress. Photo credit: NASA/Cory Huston

KSC-2012-6220

NASA Image and Video Library

2012-11-08

CAPE CANAVERAL, Fla. -- Inside the Applied Physics Laboratory in the Operations and Checkout Building at NASA’s Kennedy Space Center in Florida, lead researcher Dr. Bob Youngquist describes technologies developed for the Space Shuttle Program to a group of Society of Physics students. About 800 graduate and undergraduate physics students toured Kennedy facilities. A group of about 40 students toured laboratories in the Operations and Checkout Building and the EDL during their visit. The physics students were in Orlando for the 2012 Quadrennial Physics Congress. Photo credit: NASA/Cory Huston

The Aerospace Energy Systems Laboratory: A BITBUS networking application

NASA Technical Reports Server (NTRS)

Glover, Richard D.; Oneill-Rood, Nora

1989-01-01

The NASA Ames-Dryden Flight Research Facility developed a computerized aircraft battery servicing facility called the Aerospace Energy Systems Laboratory (AESL). This system employs distributed processing with communications provided by a 2.4-megabit BITBUS local area network. Customized handlers provide real time status, remote command, and file transfer protocols between a central system running the iRMX-II operating system and ten slave stations running the iRMX-I operating system. The hardware configuration and software components required to implement this BITBUS application are required.

A computer-based maintenance reminder and record-keeping system for clinical laboratories.

PubMed

Roberts, B I; Mathews, C L; Walton, C J; Frazier, G

1982-09-01

"Maintenance" is all the activity an organization devotes to keeping instruments within performance specifications to assure accurate and precise operation. The increasing use of complex analytical instruments as "workhorses" in clinical laboratories requires more maintenance awareness by laboratory personnel. Record-keeping systems that document maintenance completion and that should prompt the continued performance of maintenance tasks have not kept up with instrumentation development. We report here a computer-based record-keeping and reminder system that lists weekly the maintenance items due for each work station in the laboratory, including the time required to complete each item. Written in BASIC, the system uses a DATABOSS data base management system running on a time-shared Digital Equipment Corporation PDP 11/60 computer with a RSTS V 7.0 operating system.

A mobile water analysis laboratory for the study of stream nutrient and DOC dynamics

NASA Astrophysics Data System (ADS)

Echevarria Roman, Y.; Pullin, M. J.; Schwingle, R.; Gabrielsen, P. J.

2013-12-01

The dynamics of nutrient and dissolved organic carbon (DOC) quantity and composition in streams vary with season and in response to hydrologic events. Periodic grab sampling can capture some of this variation, but has also been shown to miss high flow events. Sampling during winter, during thunderstorms, and at night is difficult and sometimes hazardous. For these reasons, we have developed a mobile laboratory that autonomously determines pH, Eh, conductivity, dissolved oxygen, turbidity, nitrate, phosphate, DOC, DIC, as well as DOC fluorescence and absorbance continuously on a minutes timescale. The laboratory includes a Labview operated computer system that allows remote control and interaction with pumps, pressure, temperature, and flow sensors as well as the analytical instruments. Climate control allows for operation in winter. The design and operation of this laboratory will be presented. We will also discuss example data showing diurnal changes and responses to hydrologic events in DOC quantity and quality in the East Fork of the Jemez River, New Mexico.

Bobi A. Garrett - Deputy Laboratory Director and Chief Operating Officer

Science.gov Websites

| NREL Bobi A. Garrett - Deputy Laboratory Director and Chief Operating Officer Bobi A. Garrett - Deputy Laboratory Director and Chief Operating Officer A photo of Bobi A. Garrett, Deputy Laboratory Director and Chief Operating Officer In her role as deputy laboratory director/chief operating officer (COO

Relationship between operational variables, fundamental physics and foamed cement properties in lab and field generated foamed cement slurries

DOE PAGES

Glosser, D.; Kutchko, B.; Benge, G.; ...

2016-03-21

Foamed cement is a critical component for wellbore stability. The mechanical performance of a foamed cement depends on its microstructure, which in turn depends on the preparation method and attendant operational variables. Determination of cement stability for field use is based on laboratory testing protocols governed by API Recommended Practice 10B-4 (API RP 10B-4, 2015). However, laboratory and field operational variables contrast considerably in terms of scale, as well as slurry mixing and foaming processes. Here in this paper, laboratory and field operational processes are characterized within a physics-based framework. It is shown that the “atomization energy” imparted by themore » high pressure injection of nitrogen gas into the field mixed foamed cement slurry is – by a significant margin – the highest energy process, and has a major impact on the void system in the cement slurry. There is no analog for this high energy exchange in current laboratory cement preparation and testing protocols. Quantifying the energy exchanges across the laboratory and field processes provides a basis for understanding relative impacts of these variables on cement structure, and can ultimately lead to the development of practices to improve cement testing and performance.« less

21 CFR 58.49 - Laboratory operation areas.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 21 Food and Drugs 1 2013-04-01 2013-04-01 false Laboratory operation areas. 58.49 Section 58.49... LABORATORY PRACTICE FOR NONCLINICAL LABORATORY STUDIES Facilities § 58.49 Laboratory operation areas... procedures required by nonclinical laboratory studies. [52 FR 33780, Sept. 4, 1987] ...

21 CFR 58.49 - Laboratory operation areas.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 21 Food and Drugs 1 2012-04-01 2012-04-01 false Laboratory operation areas. 58.49 Section 58.49... LABORATORY PRACTICE FOR NONCLINICAL LABORATORY STUDIES Facilities § 58.49 Laboratory operation areas... procedures required by nonclinical laboratory studies. [52 FR 33780, Sept. 4, 1987] ...

21 CFR 58.49 - Laboratory operation areas.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 21 Food and Drugs 1 2011-04-01 2011-04-01 false Laboratory operation areas. 58.49 Section 58.49... LABORATORY PRACTICE FOR NONCLINICAL LABORATORY STUDIES Facilities § 58.49 Laboratory operation areas... procedures required by nonclinical laboratory studies. [52 FR 33780, Sept. 4, 1987] ...

Development of a paperless, Y2K compliant exposure tracking database at Los Alamos National Laboratory.

PubMed

Conwell, J L; Creek, K L; Pozzi, A R; Whyte, H M

2001-02-01

The Industrial Hygiene and Safety Group at Los Alamos National Laboratory (LANL) developed a database application known as IH DataView, which manages industrial hygiene monitoring data. IH DataView replaces a LANL legacy system, IHSD, that restricted user access to a single point of data entry needed enhancements that support new operational requirements, and was not Year 2000 (Y2K) compliant. IH DataView features a comprehensive suite of data collection and tracking capabilities. Through the use of Oracle database management and application development tools, the system is Y2K compliant and Web enabled for easy deployment and user access via the Internet. System accessibility is particularly important because LANL operations are spread over 43 square miles, and industrial hygienists (IHs) located across the laboratory will use the system. IH DataView shows promise of being useful in the future because it eliminates these problems. It has a flexible architecture and sophisticated capability to collect, track, and analyze data in easy-to-use form.

Making adaptable systems work for mission operations: A case study

NASA Technical Reports Server (NTRS)

Holder, Barbara E.; Levesque, Michael E.

1993-01-01

The Advanced Multimission Operations System (AMMOS) at NASA's Jet Propulsion Laboratory is based on a highly adaptable multimission ground data system (MGDS) for mission operations. The goal for MGDS is to support current flight project science and engineering personnel and to meet the demands of future missions while reducing associated operations and software development costs. MGDS has become a powerful and flexible mission operations system by using a network of heterogeneous workstations, emerging open system standards, and selecting an adaptable tools-based architecture. Challenges in developing adaptable systems for mission operations and the benefits of this approach are described.

Simulator for SUPO, a Benchmark Aqueous Homogeneous Reactor (AHR)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Klein, Steven Karl; Determan, John C.

2015-10-14

A simulator has been developed for SUPO (Super Power) an aqueous homogeneous reactor (AHR) that operated at Los Alamos National Laboratory (LANL) from 1951 to 1974. During that period SUPO accumulated approximately 600,000 kWh of operation. It is considered the benchmark for steady-state operation of an AHR. The SUPO simulator was developed using the process that resulted in a simulator for an accelerator-driven subcritical system, which has been previously reported.

Antimicrobial Testing Methods & Procedures Developed by EPA's Microbiology Laboratory

EPA Pesticide Factsheets

We develop antimicrobial testing methods and standard operating procedures to measure the effectiveness of hard surface disinfectants against a variety of microorganisms. Find methods and procedures for antimicrobial testing.

Components of laboratory accreditation.

PubMed

Royal, P D

1995-12-01

Accreditation or certification is a recognition given to an operation or product that has been evaluated against a standard; be it regulatory or voluntary. The purpose of accreditation is to provide the consumer with a level of confidence in the quality of operation (process) and the product of an organization. Environmental Protection Agency/OCM has proposed the development of an accreditation program under National Environmental Laboratory Accreditation Program for Good Laboratory Practice (GLP) laboratories as a supplement to the current program. This proposal was the result of the Inspector General Office reports that identified weaknesses in the current operation. Several accreditation programs can be evaluated and common components identified when proposing a structure for accrediting a GLP system. An understanding of these components is useful in building that structure. Internationally accepted accreditation programs provide a template for building a U.S. GLP accreditation program. This presentation will discuss the traditional structure of accreditation as presented in the Organization of Economic Cooperative Development/GLP program, ISO-9000 Accreditation and ISO/IEC Guide 25 Standard, and the Canadian Association for Environmental Analytical Laboratories, which has a biological component. Most accreditation programs are managed by a recognized third party, either privately or with government oversight. Common components often include a formal review of required credentials to evaluate organizational structure, a site visit to evaluate the facility, and a performance evaluation to assess technical competence. Laboratory performance is measured against written standards and scored. A formal report is then sent to the laboratory indicating accreditation status. Usually, there is a scheduled reevaluation built into the program. Fee structures vary considerably and will need to be examined closely when building a GLP program.

Stationary Engineering Laboratory Manual--2.

ERIC Educational Resources Information Center

Steingress, Frederick M.; Frost, Harold J.

The Stationary Engineering Laboratory Manual 2 was designed for vocational/technical high school students who have received instruction in the basics of stationary engineering. It was developed for students who will be operating a live plant and who will be responsible for supplying steam for heating, cooking, and baking. Each lesson in the manual…

An Internet-Based Distributed Laboratory for Interactive Chemical Engineering Education

ERIC Educational Resources Information Center

Guo, Jing; Kettler, David J.; Al-Dahhan, Muthanna

2007-01-01

A common undergraduate chemical engineering experiment has been modified for on-line operation over the Internet. By adopting rapidly changing Internet and object component technologies, we developed a novel approach combining the Internet and regular laboratory equipment. The client-server applications use a Visual Basic and Labtech programming…

21 CFR 58.49 - Laboratory operation areas.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 21 Food and Drugs 1 2010-04-01 2010-04-01 false Laboratory operation areas. 58.49 Section 58.49... LABORATORY PRACTICE FOR NONCLINICAL LABORATORY STUDIES Facilities § 58.49 Laboratory operation areas. Separate laboratory space shall be provided, as needed, for the performance of the routine and specialized...

A Unique BSL-3 Cryo-Electron Microscopy Laboratory at UTMB

PubMed Central

Sherman, Michael B.; Freiberg, Alexander N.; Razmus, Dennis; Yazuka, Shintaro; Koht, Craig; Hilser, Vincent J.; Lemon, Stanley M.; Brocard, Anne-Sophie; Zimmerman, Dee; Chiu, Wah; Watowich, Stanley J.; Weaver, Scott C.

2010-01-01

This article describes a unique cryo-electron microscopy (CryoEM) facility to study the three-dimensional organization of viruses at biological safety level 3 (BSL-3). This facility, the W. M. Keck Center for Virus Imaging, has successfully operated for more than a year without incident and was cleared for select agent studies by the Centers for Disease Control and Prevention (CDC). Standard operating procedures for the laboratory were developed and implemented to ensure its safe and efficient operation. This facility at the University of Texas Medical Branch (Galveston, TX) is the only such BSL-3 CryoEM facility approved for select agent research. PMID:21852942

Operation of Grid-tied 5 kWDC solar array to develop Laboratory Experiments for Solar PV Energy System courses

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ramos, Jaime

2012-12-14

To unlock the potential of micro grids we plan to build, commission and operate a 5 kWDC PV array and integrate it to the UTPA Engineering building low voltage network, as a micro grid; and promote community awareness. Assisted by a solar radiation tracker providing on-line information of its measurements and performing analysis for the use by the scientific and engineering community, we will write, perform and operate a set of Laboratory experiments and computer simulations supporting Electrical Engineering (graduate and undergraduate) courses on Renewable Energy, as well as Senior Design projects.

40 CFR 160.49 - Laboratory operation areas.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Laboratory operation areas. 160.49 Section 160.49 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE PROGRAMS GOOD LABORATORY PRACTICE STANDARDS Facilities § 160.49 Laboratory operation areas. Separate laboratory...

40 CFR 160.49 - Laboratory operation areas.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 24 2011-07-01 2011-07-01 false Laboratory operation areas. 160.49 Section 160.49 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE PROGRAMS GOOD LABORATORY PRACTICE STANDARDS Facilities § 160.49 Laboratory operation areas. Separate laboratory...

International Cooperation of Payload Operations on the International Space Station

NASA Technical Reports Server (NTRS)

Melton, Tina; Onken, Jay

2003-01-01

One of the primary goals of the International Space Station (ISS) is to provide an orbiting laboratory to be used to conduct scientific research and commercial products utilizing the unique environment of space. The ISS Program has united multiple nations into a coalition with the objective of developing and outfitting this orbiting laboratory and sharing in the utilization of the resources available. The primary objectives of the real- time integration of ISS payload operations are to ensure safe operations of payloads, to avoid mutual interference between payloads and onboard systems, to monitor the use of integrated station resources and to increase the total effectiveness of ISS. The ISS organizational architecture has provided for the distribution of operations planning and execution functions to the organizations with expertise to perform each function. Each IPP is responsible for the integration and operations of their payloads within their resource allocations and the safety requirements defined by the joint program. Another area of international cooperation is the sharing in the development and on- orbit utilization of unique payload facilities. An example of this cooperation is the Microgravity Science Glovebox. The hardware was developed by ESA and provided to NASA as part of a barter arrangement.

Operating characteristic analysis of a 400 mH class HTS DC reactor in connection with a laboratory scale LCC type HVDC system

NASA Astrophysics Data System (ADS)

Kim, Sung-Kyu; Kim, Kwangmin; Park, Minwon; Yu, In-Keun; Lee, Sangjin

2015-11-01

High temperature superconducting (HTS) devices are being developed due to their advantages. Most line commutated converter based high voltage direct current (HVDC) transmission systems for long-distance transmission require large inductance of DC reactor; however, generally, copper-based reactors cause a lot of electrical losses during the system operation. This is driving researchers to develop a new type of DC reactor using HTS wire. The authors have developed a 400 mH class HTS DC reactor and a laboratory scale test-bed for line-commutated converter type HVDC system and applied the HTS DC reactor to the HVDC system to investigate their operating characteristics. The 400 mH class HTS DC reactor is designed using a toroid type magnet. The HVDC system is designed in the form of a mono-pole system with thyristor-based 12-pulse power converters. In this paper, the investigation results of the HTS DC reactor in connection with the HVDC system are described. The operating characteristics of the HTS DC reactor are analyzed under various operating conditions of the system. Through the results, applicability of an HTS DC reactor in an HVDC system is discussed in detail.

Dual Arm Work Package performance estimates and telerobot task network simulation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Draper, J.V.; Blair, L.M.

1997-02-01

This paper describes the methodology and results of a network simulation study of the Dual Arm Work Package (DAWP), to be employed for dismantling the Argonne National Laboratory CP-5 reactor. The development of the simulation model was based upon the results of a task analysis for the same system. This study was performed by the Oak Ridge National Laboratory (ORNL), in the Robotics and Process Systems Division. Funding was provided the US Department of Energy`s Office of Technology Development, Robotics Technology Development Program (RTDP). The RTDP is developing methods of computer simulation to estimate telerobotic system performance. Data were collectedmore » to provide point estimates to be used in a task network simulation model. Three skilled operators performed six repetitions of a pipe cutting task representative of typical teleoperation cutting operations.« less

Development and Use of a Web Site with Multimedia Contents as a Complement to Traditional Unit Operations Courses

ERIC Educational Resources Information Center

Tapia, Cristian; Muller, Mauricio; Sapag-Hagar, Jaime; Valenzuela, Fernando; Basualto, Carlos; Abugoch, Lilian

2005-01-01

The Unit Operations Laboratory offers 2 courses in unit operations. One is a 2-semester course for chemistry and food engineering students that is more demanding because it considers more unit operations and places more emphasis on solving exercises. The other is a 1-semester course for chemistry and pharmacy students that considers fewer unit…

Agile Development Methods for Space Operations

NASA Technical Reports Server (NTRS)

Trimble, Jay; Webster, Chris

2012-01-01

Main stream industry software development practice has gone from a traditional waterfall process to agile iterative development that allows for fast response to customer inputs and produces higher quality software at lower cost. How can we, the space ops community, adopt state of the art software development practice, achieve greater productivity at lower cost, and maintain safe and effective space flight operations? At NASA Ames, we are developing Mission Control Technologies Software, in collaboration with Johnson Space Center (JSC) and, more recently, the Jet Propulsion Laboratory (JPL).

The Effect of the Laboratory Specimen on Fatigue Crack Growth Rate

NASA Technical Reports Server (NTRS)

Forth, S. C.; Johnston, W. M.; Seshadri, B. R.

2006-01-01

Over the past thirty years, laboratory experiments have been devised to develop fatigue crack growth rate data that is representative of the material response. The crack growth rate data generated in the laboratory is then used to predict the safe operating envelope of a structure. The ability to interrelate laboratory data and structural response is called similitude. In essence, a nondimensional term, called the stress intensity factor, was developed that includes the applied stresses, crack size and geometric configuration. The stress intensity factor is then directly related to the rate at which cracks propagate in a material, resulting in the material property of fatigue crack growth response. Standardized specimen configurations and experimental procedures have been developed for laboratory testing to generate crack growth rate data that supports similitude of the stress intensity factor solution. In this paper, the authors present laboratory fatigue crack growth rate test data and finite element analyses that show similitude between standard specimen configurations tested using the constant stress ratio test method is unobtainable.

The Gravity Recovery and Interior Laboratory Mission

NASA Technical Reports Server (NTRS)

Lehman, David H.; Hoffman, Tom L.; Havens, Glen G.

2013-01-01

The Gravity Recovery and Interior Laboratory (GRAIL) mission, launched in September 2011, successfully completed its Primary Science Mission in June 2012 and is currently in Extended Mission operations. Competitively selected under a NASA Announcement of Opportunity in December 2007, GRAIL is a Discovery Program mission subject to a mandatory project cost cap. The purpose of the mission is to precisely map the gravitational field of the Moon to reveal its internal structure from crust to core, determine its thermal evolution, and extend this knowledge to other planets. The mission uses twin spacecraft flying in tandem to provide the gravity map. The GRAIL Flight System, consisting of the spacecraft and payload, was developed based on significant heritage from previous missions such an experimental U.S. Air Force satellite, the Mars Reconnaissance Orbiter (MRO) mission, and the Gravity Recovery and Climate Experiment (GRACE) mission. The Mission Operations System (MOS) was based on high-heritage multimission operations developed by NASA's Jet Propulsion Laboratory and Lockheed Martin. Both the Flight System and MOS were adapted to meet the unique challenges posed by the GRAIL mission design. This paper summarizes the implementation challenges and accomplishments of getting GRAIL ready for launch. It also discusses the in-flight challenges and experiences of operating two spacecraft, and mission results.

Developing and Demonstrating an Augmented Reality Colorimetric Titration Tool

ERIC Educational Resources Information Center

Tee, Nicholas Yee Kwang; Gan, Hong Seng; Li, Jonathan; Cheong, Brandon Huey-Ping; Tan, Han Yen; Liew, Oi Wah; Ng, Tuck Wah

2018-01-01

The handling of chemicals in the laboratory presents a challenge in instructing large class sizes and when students are relatively new to the laboratory environment. In this work, we describe and demonstrate an augmented reality colorimetric titration tool that operates out of the smartphone or tablet of students. It allows multiple students to…

Effluent-Monitoring Procedures: Basic Laboratory Skills. Student Reference Manual.

ERIC Educational Resources Information Center

Engel, William T.; And Others

This is one of several short-term courses developed to assist in the training of waste water treatment plant operational personnel in the tests, measurements, and report preparation required for compliance with their NPDES Permits. This Student Reference Manual provides a review of basic mathematics as it applies to the chemical laboratory. The…

Solid-Liquid and Liquid-Liquid Mixing Laboratory for Chemical Engineering Undergraduates

ERIC Educational Resources Information Center

Pour, Sanaz Barar; Norca, Gregory Benoit; Fradette, Louis; Legros, Robert; Tanguy, Philippe A.

2007-01-01

Solid-liquid and liquid-liquid mixing experiments have been developed to provide students with a practical experience on suspension and emulsification processes. The laboratory focuses on the characterization of the process efficiency, specifically the influence of the main operating parameters and the effect of the impeller type. (Contains 2…

Stationary Engineering Laboratory--2. Teacher's Guide.

ERIC Educational Resources Information Center

Steingress, Frederick M.; Frost, Harold J.

The Stationary Engineering Laboratory Manual 2 Teacher's Guide was designed as an aid to the instructors of vocational-technical high school students who have received instruction in the basics of stationary engineering. The course of study was developed for students who will be operating a live plant and who will be responsible for supplying…

DOE Office of Scientific and Technical Information (OSTI.GOV)

Glosser, D.; Kutchko, B.; Benge, G.

Foamed cement is a critical component for wellbore stability. The mechanical performance of a foamed cement depends on its microstructure, which in turn depends on the preparation method and attendant operational variables. Determination of cement stability for field use is based on laboratory testing protocols governed by API Recommended Practice 10B-4 (API RP 10B-4, 2015). However, laboratory and field operational variables contrast considerably in terms of scale, as well as slurry mixing and foaming processes. Here in this paper, laboratory and field operational processes are characterized within a physics-based framework. It is shown that the “atomization energy” imparted by themore » high pressure injection of nitrogen gas into the field mixed foamed cement slurry is – by a significant margin – the highest energy process, and has a major impact on the void system in the cement slurry. There is no analog for this high energy exchange in current laboratory cement preparation and testing protocols. Quantifying the energy exchanges across the laboratory and field processes provides a basis for understanding relative impacts of these variables on cement structure, and can ultimately lead to the development of practices to improve cement testing and performance.« less

40 CFR 792.49 - Laboratory operation areas.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 32 2011-07-01 2011-07-01 false Laboratory operation areas. 792.49... CONTROL ACT (CONTINUED) GOOD LABORATORY PRACTICE STANDARDS Facilities § 792.49 Laboratory operation areas. Separate laboratory space and other space shall be provided, as needed, for the performance of the routine...

Implementation of the OECD principles of good laboratory practice in test facilities complying with a quality system accredited to the ISO/IEC 17025 standard.

PubMed

Feller, Etty

2008-01-01

Laboratories with a quality system accredited to the ISO/IEC 17025 standard have a definite advantage, compared to non-accredited laboratories, when preparing their facilities for the implementation of the principles of good laboratory practice (GLP) of the Organisation for Economic Co-operation and Development (OECD). Accredited laboratories have an established quality system covering the administrative and technical issues specified in the standard. The similarities and differences between the ISO/IEC 17025 standard and the OECD principles of GLP are compared and discussed.

Comparison Between Simulated and Experimentally Measured Performance of a Four Port Wave Rotor

NASA Technical Reports Server (NTRS)

Paxson, Daniel E.; Wilson, Jack; Welch, Gerard E.

2007-01-01

Performance and operability testing has been completed on a laboratory-scale, four-port wave rotor, of the type suitable for use as a topping cycle on a gas turbine engine. Many design aspects, and performance estimates for the wave rotor were determined using a time-accurate, one-dimensional, computational fluid dynamics-based simulation code developed specifically for wave rotors. The code follows a single rotor passage as it moves past the various ports, which in this reference frame become boundary conditions. This paper compares wave rotor performance predicted with the code to that measured during laboratory testing. Both on and off-design operating conditions were examined. Overall, the match between code and rig was found to be quite good. At operating points where there were disparities, the assumption of larger than expected internal leakage rates successfully realigned code predictions and laboratory measurements. Possible mechanisms for such leakage rates are discussed.

Integrating research into operational practice

PubMed Central

Ross, Alastair

2015-01-01

Research and development can be classified into three categories: technology adoption, technology extension, and knowledge and technology creation. In general, technology adoption is embedded in operational forensic science laboratory practice but the latter two categories require partnerships with industry and/or academia both to conduct the research and implement the outcomes. In a 2012 survey, Australian and New Zealand forensic science laboratories identified a number of ‘roadblocks’ to undertaking research and operationalizing research outcomes. These included insufficient time and funding, a lack of in-house research experience and the absence of a tangible research culture. Allied to this is that, increasingly, forensic science research is conducted in a ‘commercial in confidence’ environment and the outcomes are not readily or cost-effectively available to be integrated into operational forensic science laboratories. The paper is predominantly reflective of the current situation in Australia and New Zealand PMID:26101286

[Microsurgery, a 'small' surgical revolution in the medical history of the 20th century].

PubMed

Haeseker, B

1999-04-17

Microsurgery in the twentieth century enabled surgeons to operate on very fine structures, which was impossible before the advent of the microscope. Since 1860 loupe magnification was employed in rare cases. In 1921 Nylén from Sweden transformed an ordinary laboratory microscope into an operation microscope for ear interventions. The eye specialists were the second group of doctors who employed the microscope in the operating theatre during the years 40-50 of this century. Since 1953 Zeiss in Germany has produced highly professional operation microscopes. In the sixties experimental laboratory studies were taken up to develop microsurgical techniques, microinstruments and suture material. Both plastic and reconstructive surgeons and neurosurgeons continued to develop microsurgery and indeed transformed their disciplines a great deal. Microsurgery is here to stay and still experiments are going on with video-assisted systems in order to further miniaturize the instruments for magnification and to gain a more comfortable working position for the surgeon.

Human operator performance of remotely controlled tasks: Teleoperator research conducted at NASA's George C. Marshall Space Flight Center. Executive summary

NASA Technical Reports Server (NTRS)

Shields, N., Jr.; Piccione, F.; Kirkpatrick, M., III; Malone, T. B.

1982-01-01

The combination of human and machine capabilities into an integrated engineering system which is complex and interactive interdisciplinary undertaking is discussed. Human controlled remote systems referred to as teleoperators, are reviewed. The human factors requirements for remotely manned systems are identified. The data were developed in three principal teleoperator laboratories and the visual, manipulator and mobility laboratories are described. Three major sections are identified: (1) remote system components, (2) human operator considerations; and (3) teleoperator system simulation and concept verification.

A new generation of high-performance operational quantum sensors (Conference Presentation)

NASA Astrophysics Data System (ADS)

Lautier-Gaud, Jean; Desruelle, Bruno; Ménoret, Vincent; Schaff, Jean-François; Stern, Guillaume; Vermeulen, Pierre

2016-04-01

After 30 years of academic research in cold atom sciences, intensive developments are being conducted to improve the compactness and the reliability of experimental set-ups in order to transfer such devices from laboratory-based research to an operational utilization outside of the laboratory. We will present the long-lasting developments that we have been carrying to provide the first industrial cold-atom absolute gravimeter and the first industrial cold-atom atomic clock. We will present in detail the principles of operation and the main features of our instruments. Their performances in terms of sensitivity, stability and accuracy and the latest results they achieved will be reviewed. We will then discuss their use to support other research activities. One of the key technology elements of such instruments that need to be addressed is the laser system used to cool down and manipulate the atoms. A specific focus on our latest developments in this area in terms of performances will be proposed.

21 CFR 111.110 - What quality control operations are required for laboratory operations associated with the...

Code of Federal Regulations, 2010 CFR

2010-04-01

... laboratory operations associated with the production and process control system? 111.110 Section 111.110 Food... OPERATIONS FOR DIETARY SUPPLEMENTS Production and Process Control System: Requirements for Quality Control... production and process control system? Quality control operations for laboratory operations associated with...

Sitewide Environmental Assessment for the National Renewable Energy Laboratory, Golden, Colorado

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1993-05-04

The Solar Energy Research, Development, and Demonstration Act of 1974 authorized a federal program to develop solar energy as a viable source of the nation`s future energy needs. Under this authority, the National Renewable Energy Laboratory (NREL) was created as a laboratory of the Department of Energy (DOE) to research a number of renewable energy possibilities. The laboratory conducts its operations both in government-owned facilities on the NREL South Table Mountain (STM) Site near Golden, Colorado, and in a number of leased facilities, particularly the Denver West Office Park. NREL operations include research in energy technologies, and other areas ofmore » national environmental and energy technology interest. Examples of these technologies include electricity from sunlight with solar cells (photovoltaics); energy from wind (windmills or wind turbines); conversion of plants and plant products (biomass) into liquid fuels (ethanol and methanol); heat from the sun (solar thermal) in place of wood, oil, gas, coal and other forms of heating; and solar buildings. NREL proposes to continue and expand the present R&D efforts in C&R energy by making infrastructure improvements and constructing facilities to eventually consolidate the R&D and associated support activities at its STM Site. In addition, it is proposed that operations continue in current leased space at the present levels of activity until site development is complete. The construction schedule proposed is designed to develop the site as rapidly as possible, dependent on Congressional funding, to accommodate not only the existing R&D that is being conducted in leased facilities off-site but to also allow for the 20-year projected growth. Impacts from operations currently conducted off-site are quantified and added to the cumulative impacts of the STM site. This environmental assessment provides information to determine the severity of impacts on the environment from the proposed action.« less

Development and experimentation of an eye/brain/task testbed

NASA Technical Reports Server (NTRS)

Harrington, Nora; Villarreal, James

1987-01-01

The principal objective is to develop a laboratory testbed that will provide a unique capability to elicit, control, record, and analyze the relationship of operator task loading, operator eye movement, and operator brain wave data in a computer system environment. The ramifications of an integrated eye/brain monitor to the man machine interface are staggering. The success of such a system would benefit users of space and defense, paraplegics, and the monitoring of boring screens (nuclear power plants, air defense, etc.)

An OSI architecture for the deep space network

NASA Technical Reports Server (NTRS)

Heuser, W. Randy; Cooper, Lynne P.

1993-01-01

The flexibility and robustness of a monitor and control system are a direct result of the underlying inter-processor communications architecture. A new architecture for monitor & Control at the Deep Space Network Communications Complexes has been developed based on the Open System Interconnection (OSI) standards. The suitability of OSI standards for DSN M&C has been proven in the laboratory. The laboratory success has resulted in choosing an OSI-based architecture for DSS-13 M&C. DSS-13 is the DSN experimental station and is not part of the 'operational' DSN; it's role is to provide an environment to test new communications concepts can be tested and conduct unique science experiments. Therefore, DSS-13 must be robust enough to support operational activities, while also being flexible enough to enable experimentation. This paper describes the M&C architecture developed for DSS-13 and the results from system and operational testing.

Cryogenic Pressure Calibrator for Wide Temperature Electronically Scanned (ESP) Pressure Modules

NASA Technical Reports Server (NTRS)

Faulcon, Nettie D.

2001-01-01

Electronically scanned pressure (ESP) modules have been developed that can operate in ambient and in cryogenic environments, particularly Langley's National Transonic Facility (NTF). Because they can operate directly in a cryogenic environment, their use eliminates many of the operational problems associated with using conventional modules at low temperatures. To ensure the accuracy of these new instruments, calibration was conducted in a laboratory simulating the environmental conditions of NTF. This paper discusses the calibration process by means of the simulation laboratory, the system inputs and outputs and the analysis of the calibration data. Calibration results of module M4, a wide temperature ESP module with 16 ports and a pressure range of +/- 4 psid are given.

Guidelines on Good Clinical Laboratory Practice

PubMed Central

Ezzelle, J.; Rodriguez-Chavez, I. R.; Darden, J. M.; Stirewalt, M.; Kunwar, N.; Hitchcock, R.; Walter, T.; D’Souza, M. P.

2008-01-01

A set of Good Clinical Laboratory Practice (GCLP) standards that embraces both the research and clinical aspects of GLP were developed utilizing a variety of collected regulatory and guidance material. We describe eleven core elements that constitute the GCLP standards with the objective of filling a gap for laboratory guidance, based on IND sponsor requirements, for conducting laboratory testing using specimens from human clinical trials. These GCLP standards provide guidance on implementing GLP requirements that are critical for laboratory operations, such as performance of protocol-mandated safety assays, peripheral blood mononuclear cell processing and immunological or endpoint assays from biological interventions on IND-registered clinical trials. The expectation is that compliance with the GCLP standards, monitored annually by external audits, will allow research and development laboratories to maintain data integrity and to provide immunogenicity, safety, and product efficacy data that is repeatable, reliable, auditable and that can be easily reconstructed in a research setting. PMID:18037599

The manned space-laboratories control centre - MSCC. Operational functions and its implementation

NASA Astrophysics Data System (ADS)

Brogl, H.; Kehr, J.; Wlaka, M.

This paper describes the functions of the MSCC during the operations of the Columbus Attached Laboratory and the Free Flying Laboratory as part of the In-Orbit-Infrastructure Ground Segment. For the Attached Laboratory, MSCC payload operations coordination for European experiments within the Attached Laboratory and elsewhere on the Space Station Freedom will be explained. The Free Flying Laboratory will be operated and maintained exclusively from the MSCC during its 30 years lifetime. Several operational scenarios will demonstrate the role of the MSCC during routine - and servicing operations: of main importance are the servicing activities of the Attached Laboratory and the Free Flyer at the Space Station as well as servicing of the Free Flyer by the European Space Plane Hermes. The MSCC will have complex operational-, communications-and management interfaces with the IOI Ground Segment, the Space Station User community and with the international partners. Columbus User Support Centres will be established in many European member states, which have to be coordinated by the MSCC to ensure the proper reception of the scientific data and to provide them with quick access to their experiments in space. For operations planning and execution of experiments in the Attached Laboratory, a close cooperation with the Space Station control authorities in the USA will be established. The paper will show the development of the MSCC being initially used for the upcoming Spacelab Mission D-2 (MSCC Phase-1) and later upgraded to a Columbus dedicated control centre (MSCC Phase-2). For the initial construction phase the establishing of MSCC requirements, the philosophie used for the definition of the 'basic infrastructure' and key features of the installed facilities will be addressed. Resulting from Columbus and D-2 requirements, the sizing of the building with respect to controlrooms, conference rooms, office spare and simulation high-bay areas will be discussed. The defined 'basic infrastructure', consisting of standardized controlroom consoles, intercom system, video system, simulation system, timing system, public address system, office communications system and the associated networks will be presented with their main performance data. The D-2 data processing concept and associated interfaces is presented as well; although this portion of the MSCC facilities is unlikely to be used in later IOI operations activities the experience gathered during D-2 operations will be relevant for defining the Columbus (MSCC - Phase 2) configuration. A summary of the available budget and the allocation to the discussed MSCC Phase-1 facilities will be given. One chapter of the paper will present the current status and objectives of the Detailed Definition Phase (DDP) contract with industry. The last part of this presentation will address the planned implementation integration and test approach for the MSCC as a facility suitable for Columbus operations.

Development and operation of a mobile test facility for education

NASA Astrophysics Data System (ADS)

Davis, Christopher T.

The automotive industry saw a large shift towards vehicle electrification after the turn of the century. It became necessary to ensure that new and existing engineers were qualified to design and calibrate these new systems. To ensure this training, Michigan Tech received a grant to develop a curriculum based around vehicle electrification. As part of this agenda, the Michigan Tech Mobile Laboratory was developed to provide hands-on training for professional engineers and technicians in hybrid electric vehicles and vehicle electrification. The Mobile Lab has since then increased the scope of the delivered curriculum to include other automotive areas and even customizable course content to meet specific needs. This thesis outlines the development of the Mobile Laboratory and its powertrain test facilities. The focus of this thesis is to discuss the different hardware and software systems within the lab and test cells. Detailed instructions on the operation and maintenance of each of the systems are discussed. In addition, this thesis outlines the setup and operation of the necessary equipment for several of the experiments for the on and off campus courses and seminars.

Tailpipe emissions and engine performance of a light-duty diesel engine operating on petro- and bio-diesel fuel blends.

DOT National Transportation Integrated Search

2014-06-01

This report summarizes the experimental apparatus developed in the Transportation Air Quality Laboratory (TAQ Lab) at the University of Vermont to compare light-duty diesel engine performance and exhaust emissions when operating on petroleum diesel (...

Air Force Research Laboratory Success Stories. A Review of 2003

DTIC Science & Technology

2003-01-01

Metal -Polymer Hybrid Signal Wiring for Aircraft and Spacecraft 27 Engineers Develop First Response Expeditionary Fire Vehicle 28 Engineers Rapidly...operational committees. Mr. Bruce Rasmussen and Mr. Juan Calzada, of the directorate’s Metals , Ceramics, and Nondestructive Evaluation Division; Mr...be the solution, since they provided a more efficient method of running the depot operation. Researchers Develop High-Performance, Metal -Polymer

Analytical control test plan and microbiological methods for the water recovery test

NASA Technical Reports Server (NTRS)

Traweek, M. S. (Editor); Tatara, J. D. (Editor)

1994-01-01

Qualitative and quantitative laboratory results are important to the decision-making process. In some cases, they may represent the only basis for deciding between two or more given options or processes. Therefore, it is essential that handling of laboratory samples and analytical operations employed are performed at a deliberate level of conscientious effort. Reporting erroneous results can lead to faulty interpretations and result in misinformed decisions. This document provides analytical control specifications which will govern future test procedures related to all Water Recovery Test (WRT) Phase 3 activities to be conducted at the National Aeronautics and Space Administration/Marshall Space Flight Center (NASA/MSFC). This document addresses the process which will be used to verify analytical data generated throughout the test period, and to identify responsibilities of key personnel and participating laboratories, the chains of communication to be followed, and ensure that approved methodology and procedures are used during WRT activities. This document does not outline specifics, but provides a minimum guideline by which sampling protocols, analysis methodologies, test site operations, and laboratory operations should be developed.

Performance model for grid-connected photovoltaic inverters.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Boyson, William Earl; Galbraith, Gary M.; King, David L.

2007-09-01

This document provides an empirically based performance model for grid-connected photovoltaic inverters used for system performance (energy) modeling and for continuous monitoring of inverter performance during system operation. The versatility and accuracy of the model were validated for a variety of both residential and commercial size inverters. Default parameters for the model can be obtained from manufacturers specification sheets, and the accuracy of the model can be further refined using measurements from either well-instrumented field measurements in operational systems or using detailed measurements from a recognized testing laboratory. An initial database of inverter performance parameters was developed based on measurementsmore » conducted at Sandia National Laboratories and at laboratories supporting the solar programs of the California Energy Commission.« less

Guidelines for safe work practices in human and animal medical diagnostic laboratories. Recommendations of a CDC-convened, Biosafety Blue Ribbon Panel.

PubMed

Miller, J Michael; Astles, Rex; Baszler, Timothy; Chapin, Kimberle; Carey, Roberta; Garcia, Lynne; Gray, Larry; Larone, Davise; Pentella, Michael; Pollock, Anne; Shapiro, Daniel S; Weirich, Elizabeth; Wiedbrauk, Danny

2012-01-06

Prevention of injuries and occupational infections in U.S. laboratories has been a concern for many years. CDC and the National Institutes of Health addressed the topic in their publication Biosafety in Microbiological and Biomedical Laboratories, now in its 5th edition (BMBL-5). BMBL-5, however, was not designed to address the day-to-day operations of diagnostic laboratories in human and animal medicine. In 2008, CDC convened a Blue Ribbon Panel of laboratory representatives from a variety of agencies, laboratory organizations, and facilities to review laboratory biosafety in diagnostic laboratories. The members of this panel recommended that biosafety guidelines be developed to address the unique operational needs of the diagnostic laboratory community and that they be science based and made available broadly. These guidelines promote a culture of safety and include recommendations that supplement BMBL-5 by addressing the unique needs of the diagnostic laboratory. They are not requirements but recommendations that represent current science and sound judgment that can foster a safe working environment for all laboratorians. Throughout these guidelines, quality laboratory science is reinforced by a common-sense approach to biosafety in day-to-day activities. Because many of the same diagnostic techniques are used in human and animal diagnostic laboratories, the text is presented with this in mind. All functions of the human and animal diagnostic laboratory--microbiology, chemistry, hematology, and pathology with autopsy and necropsy guidance--are addressed. A specific section for veterinary diagnostic laboratories addresses the veterinary issues not shared by other human laboratory departments. Recommendations for all laboratories include use of Class IIA2 biological safety cabinets that are inspected annually; frequent hand washing; use of appropriate disinfectants, including 1:10 dilutions of household bleach; dependence on risk assessments for many activities; development of written safety protocols that address the risks of chemicals in the laboratory; the need for negative airflow into the laboratory; areas of the laboratory in which use of gloves is optional or is recommended; and the national need for a central site for surveillance and nonpunitive reporting of laboratory incidents/exposures, injuries, and infections.

Scientific Hybrid Reality Environments (SHyRE): Bringing Field Work into the Laboratory

NASA Astrophysics Data System (ADS)

Miller, M. J.; Graff, T.; Young, K.; Coan, D.; Whelley, P.; Richardson, J.; Knudson, C.; Bleacher, J.; Garry, W. B.; Delgado, F.; Noyes, M.; Valle, P.; Buffington, J.; Abercromby, A.

2018-04-01

The SHyRE program aims to develop a scientifically-robust analog environment using a new and innovative hybrid reality setting that enables frequent operational testing and rapid protocol development for future planetary exploration.

SYSTEM DESIGN FOR A CONTINUOUS PROGRESS SCHOOL--PART III, THE INSTRUCTIONAL MATERIALS CENTER.

ERIC Educational Resources Information Center

COGSWELL, JOHN F.; EGBERT, ROBERT L.

THE INSTRUCTIONAL MATERIALS CENTER (IMC) OF THE CONTINUOUS PROGRESS SCHOOL WAS DESCRIBED. THE CONTINUOUS PROGRESS SCHOOL PLAN WAS DEVISED BY DR. EDWIN READ AND WAS BEING DEVELOPED AT THE LABORATORY SCHOOL OF BRIGHAM YOUNG UNIVERSITY. THIS REPORT DESCRIBED HOW AN IMC MIGHT OPERATE RATHER THAN HOW ONE IS OPERATING OR IS PLANNED TO OPERATE. AS…

Theoretical and practical considerations for teaching diagnostic electronic-nose technologies to clinical laboratory technicians

Treesearch

Alphus D. Wilson

2012-01-01

The rapid development of new electronic technologies and instruments, utilized to perform many current clinical operations in the biomedical field, is changing the way medical health care is delivered to patients. The majority of test results from laboratory analyses, performed with these analytical instruments often prior to clinical examinations, are frequently used...

An Embedded Systems Laboratory to Support Rapid Prototyping of Robotics and the Internet of Things

ERIC Educational Resources Information Center

Hamblen, J. O.; van Bekkum, G. M. E.

2013-01-01

This paper describes a new approach for a course and laboratory designed to allow students to develop low-cost prototypes of robotic and other embedded devices that feature Internet connectivity, I/O, networking, a real-time operating system (RTOS), and object-oriented C/C++. The application programming interface (API) libraries provided permit…

An expanded safeguards role for the DOE safeguards analytical laboratory

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bingham, C.D.

The New Brunswick Laboratory (NBL) is a Government-owned, Government-operated (GOGO) laboratory, with the mission to provide and maintain a nuclear material measurements and standards laboratory. The functional responsibilities of NBL serve as a technical response to the statutory responsibility of the Department of Energy (DOE) to assure the safeguarding of nuclear materials. In the execution of its mission, NBL carries out activities in six safeguards-related programs: measurement development, measurement evaluation, measurement services, safeguards assessment, reference and calibration materials and site-specific assistance. These program activities have been implemented by NBL for many years; their relative emphases, however, have been changed recentlymore » to address the priorities defined by the DOE Office of Safeguards and Security, Defense Programs (OSS/DP). As a consequence, NBL operations are in the ''mainstream'' of domestic safeguards activities. This expanded safeguards role for NBL is discussed in this paper.« less

Factors affecting the labor efficiency of hospital-based blood bank laboratories.

PubMed

Lam, H C; Kominski, G F; Petz, L D; Sofaer, S

1994-09-01

A variety of financing mechanisms and managerial innovations have been developed in the past decade to control hospital costs. Some evidence suggests that those changes have not produced substantial improvements in labor efficiency among employees in the hospital's technical level, such as in the blood bank laboratories. This study measured labor efficiency in 40 hospital-based blood bank laboratories in Southern California during the year from July 1989 to June 1990 and explored the impact of financial, managerial, and operational factors on labor efficiency. With standardized output measures used in all blood bank laboratories, a wide variation of labor efficiency was found. Multivariate analyses indicate that the labor efficiency of blood bank employees was not influenced by organizational financial incentives, but was affected by the managerial styles of blood bank managers. Interpretation of the findings suggests that labor efficiency is affected by operational designs intended to improve responses to variable workloads and reduce slack time.

A Multi-mission Event-Driven Component-Based System for Support of Flight Software Development, ATLO, and Operations first used by the Mars Science Laboratory (MSL) Project

NASA Technical Reports Server (NTRS)

Dehghani, Navid; Tankenson, Michael

2006-01-01

This viewgraph presentation reviews the architectural description of the Mission Data Processing and Control System (MPCS). MPCS is an event-driven, multi-mission ground data processing components providing uplink, downlink, and data management capabilities which will support the Mars Science Laboratory (MSL) project as its first target mission. MPCS is designed with these factors (1) Enabling plug and play architecture (2) MPCS has strong inheritance from GDS components that have been developed for other Flight Projects (MER, MRO, DAWN, MSAP), and are currently being used in operations and ATLO, and (3) MPCS components are Java-based, platform independent, and are designed to consume and produce XML-formatted data

Development of Operational Free-Space-Optical (FSO) Laser Communication Systems Final Report CRADA No. TC02093.0

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ruggiero, A.; Orgren, A.

This project was a collaborative effort between Lawrence Livermore National Security, LLC (formerly The Regents of the University of California)/Lawrence Livermore National Laboratory (LLNL) and LGS Innovations, LLC (formerly Lucent Technologies, Inc.), to develop long-range and mobile operational free-space optical (FSO) laser communication systems for specialized government applications. LLNL and LGS Innovations formerly Lucent Bell Laboratories Government Communications Systems performed this work for a United States Government (USG) Intelligence Work for Others (I-WFO) customer, also referred to as "Government Customer", or "Customer" and "Government Sponsor." The CRADA was a critical and required part of the LLNL technology transfer plan formore » the customer.« less

40 CFR 792.49 - Laboratory operation areas.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 31 2010-07-01 2010-07-01 true Laboratory operation areas. 792.49 Section 792.49 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES CONTROL ACT (CONTINUED) GOOD LABORATORY PRACTICE STANDARDS Facilities § 792.49 Laboratory operation areas...

Life Sciences Laboratories for the Shuttle/Spacelab

NASA Technical Reports Server (NTRS)

Schulte, L. O.; Kelly, H. B.; Secord, T. C.

1976-01-01

Space Shuttle and Spacelab missions will provide scientists with their first opportunity to participate directly in research in space for all scientific disciplines, particularly the Life Sciences. Preparations are already underway to ensure the success of these missions. The paper summarizes the results of the 1975 NASA-funded Life Sciences Laboratories definition study which defined several long-range life sciences research options and the laboratory designs necessary to accomplish high-priority life sciences research. The implications and impacts of Spacelab design and development on the life sciences missions are discussed. An approach is presented based upon the development of a general-purposs laboratory capability and an inventory of common operational research equipment for conducting life sciences research. Several life sciences laboratories and their capabilities are described to demonstrate the systems potentially available to the experimenter for conducting biological and medical research.

Practical experience with graphical user interfaces and object-oriented design in the clinical laboratory.

PubMed

Wells, I G; Cartwright, R Y; Farnan, L P

1993-12-15

The computing strategy in our laboratories evolved from research in Artificial Intelligence, and is based on powerful software tools running on high performance desktop computers with a graphical user interface. This allows most tasks to be regarded as design problems rather than implementation projects, and both rapid prototyping and an object-oriented approach to be employed during the in-house development and enhancement of the laboratory information systems. The practical application of this strategy is discussed, with particular reference to the system designer, the laboratory user and the laboratory customer. Routine operation covers five departments, and the systems are stable, flexible and well accepted by the users. Client-server computing, currently undergoing final trials, is seen as the key to further development, and this approach to Pathology computing has considerable potential for the future.

Design and development of a solar powered mobile laboratory

NASA Astrophysics Data System (ADS)

Jiao, L.; Simon, A.; Barrera, H.; Acharya, V.; Repke, W.

2016-08-01

This paper describes the design and development of a solar powered mobile laboratory (SPML) system. The SPML provides a mobile platform that schools, universities, and communities can use to give students and staff access to laboratory environments where dedicated laboratories are not available. The lab includes equipment like 3D printers, computers, and soldering stations. The primary power source of the system is solar PV which allows the laboratory to be operated in places where the grid power is not readily available or not sufficient to power all the equipment. The main system components include PV panels, junction box, battery, charge controller, and inverter. Not only is it used to teach students and staff how to use the lab equipment, but it is also a great tool to educate the public about solar PV technologies.

Keeping It Simple: Can We Estimate Malting Quality Potential Using an Isothermal Mashing Protocol and Common Laboratory Instrumentation?

USDA-ARS?s Scientific Manuscript database

Current methods for generating malting quality metrics have been developed largely to support commercial malting and brewing operations, providing accurate, reproducible analytical data to guide malting and brewing production. Infrastructure to support these analytical operations often involves sub...

Implementation and Analysis of Hemodialysis in the Unit Operations Laboratory

ERIC Educational Resources Information Center

Madihally, Sundararajan V.; Lewis, Randy S.

2007-01-01

To enhance bioengineering in the chemical engineering curriculum, a Unit Operations experiment simulating the hemodialysis of creatinine was implemented. The blood toxin creatinine was used for developing a more realistic dialysis experiment. A dialysis model is presented that allows students to assess the validity of model assumptions. This work…

Process for Managing and Customizing HPC Operating Systems

DOE Office of Scientific and Technical Information (OSTI.GOV)

Brown, David ML

2014-04-02

A process for maintaining a custom HPC operating system was developed at the Environmental Molecular Sciences Laboratory (EMSL) over the past ten years. This process is generic and flexible to manage continuous change as well as keep systems updated while managing communication through well defined pieces of software.

Training and Tactical Operationally Responsive Space Operations

NASA Astrophysics Data System (ADS)

Sorensen, B.; Strunce, R., Jr.

Current space assets managed by traditional space system control resources provide communication, navigation, intelligence, surveillance, and reconnaissance (ISR) capabilities using satellites that are designed for long life and high reliability. The next generation Operationally Responsive Space (ORS) systems are aimed at providing operational space capabilities which will provide flexibility and responsiveness to the tactical battlefield commander. These capabilities do not exist today. The ORS communication, navigation, and ISR satellites are being designed to replace or supplement existing systems in order to enhance the current space force. These systems are expected to rapidly meet near term space needs of the tactical forces. The ORS concept includes new tactical satellites specifically designed to support contingency operations such as increased communication bandwidth and ISR imagery over the theater for a limited period to support air, ground, and naval force mission. The Concept of Operations (CONOPS) that exists today specifies that in addition to operational control of the satellite, the tasking and scheduling of the ORS tactical satellite for mission data collection in support of the tactical warfighter will be accomplished within the Virtual Mission Operations Center (VMOC). This is very similar to what is currently being accomplished in a fixed Mission Operations Center on existing traditional ISR satellites. The VMOC is merely a distributed environment and the CONOPS remain virtually the same. As a result, there is a significant drawback to the current ORS CONOPS that does not account for the full potential of the ORS paradigm for supporting tactical forces. Although the CONOPS approach may be appropriate for experimental Tactical Satellites (TacSat), it ignores the issues associated with the In-Theater Commander's need to own and operate his dedicated TacSat for most effective warfighting as well as the Warfighter specific CONOPS. What is needed to realize the full potential of the ORS approach to the support of in-theater tactical forces is the development of satellite tasking, interface, and data retrieval capabilities and mission operations approaches from a warfighter centered perspective, and the development of realistic training and simulation capabilities that will allow development, demonstration, and assessment of ORS tactical CONOPS. A system for Training and Tactical ORS Operations (TATOO) is currently being developed. This system will support development and evaluation of ORS specific CONOPS approaches, and training and evaluation of those CONOPS implementations through dedicated training capabilities, facilities, and exercises. TATOO will support the operational side of ORS and will merge with the revolutionary ORS spacecraft development and deployment processes to make the ORS paradigm a reality. TATOO's primary objective is to support the In-Theater Commander and Warfighter by developing, training, and assessing ORS mission CONOPS for In-Theater tasking, scheduling, interface, and data retrieval for TacSats owned by In-Theater Commanders. TATOO provides a laboratory/classroom environment for the development, test and evaluation of ORS Tactical Mission CONOPS for In-Theater ORS operations. The TATOO laboratory will also be used to develop, evaluate, and document ORS Mission CONOPS for tactical ISR and other ORS missions. Within this framework, the laboratory/classroom can be used to develop the necessary training materials and procedures, as well as conduct training exercises that emphasize the training of In-Theater personal with regard to: Tactical Ground Station Mission Operations; Tactical Operations for Mission Tasking and Scheduling; Tactical Mission Data Retrieval; and, Support for Warfighter Operations.

Managing the Implementation of Mission Operations Automation

NASA Technical Reports Server (NTRS)

Sodano, R.; Crouse, P.; Odendahl, S.; Fatig, M.; McMahon, K.; Lakin, J.

2006-01-01

Reducing the cost of mission operations has necessitated a high level of automation both on spacecraft and ground systems. While automation on spacecraft is implemented during the design phase, ground system automation tends to be implemented during the prime mission operations phase. Experience has shown that this tendency for late automation development can be hindered by several factors: additional hardware and software resources may need to be procured; software must be developed and tested on a non-interference basis with primary operations with limited manpower; and established procedures may not be suited for automation requiring substantial rework. In this paper we will review the experience of successfully automating mission operations for seven on-orbit missions: the Compton Gamma Ray Observatory (CGRO), the Rossi X-Ray Timing Explorer (RXTE), the Advanced Composition Explorer (ACE), the Far Ultraviolet Spectroscopic Explorer (FUSE), Interplanetary Physics Laboratory (WIND), Polar Plasma Laboratory (POLAR), and the Imager for Magnetopause-to-Aurora Global Exploration (IMAGE). We will provide lessons learned in areas such as: spacecraft recorder management, procedure development, lights out commanding from the ground system vs. stored command loads, spacecraft contingency response time, and ground station interfaces. Implementing automation strategies during the mission concept and spacecraft integration and test phase as the most efficient method will be discussed.

40 CFR 63.601 - Definitions.

Code of Federal Regulations, 2011 CFR

2011-07-01

... rendering that product suitable for industrial, manufacturing or food grade uses. Research and development facility means research or laboratory operations whose primary purpose is to conduct research and...

40 CFR 63.601 - Definitions.

Code of Federal Regulations, 2013 CFR

2013-07-01

... rendering that product suitable for industrial, manufacturing or food grade uses. Research and development facility means research or laboratory operations whose primary purpose is to conduct research and...

40 CFR 63.601 - Definitions.

Code of Federal Regulations, 2014 CFR

2014-07-01

... rendering that product suitable for industrial, manufacturing or food grade uses. Research and development facility means research or laboratory operations whose primary purpose is to conduct research and...

Collaborative engagement experiment

NASA Astrophysics Data System (ADS)

Mullens, Katherine; Troyer, Bradley; Wade, Robert; Skibba, Brian; Dunn, Michael

2006-05-01

Unmanned ground and air systems operating in collaboration have the potential to provide future Joint Forces a significant capability for operations in complex terrain. Collaborative Engagement Experiment (CEE) is a consolidation of separate Air Force, Army and Navy collaborative efforts within the Joint Robotics Program (JRP) to provide a picture of the future of unmanned warfare. The Air Force Research Laboratory (AFRL), Material and Manufacturing Directorate, Aerospace Expeditionary Force Division, Force Protection Branch (AFRL/MLQF), The Army Aviation and Missile Research, Development and Engineering Center (AMRDEC) Joint Technology Center (JTC)/Systems Integration Laboratory (SIL), and the Space and Naval Warfare Systems Center - San Diego (SSC San Diego) are conducting technical research and proof of principle experiments for an envisioned operational concept for extended range, three dimensional, collaborative operations between unmanned systems, with enhanced situational awareness for lethal operations in complex terrain. This paper describes the work by these organizations to date and outlines some of the plans for future work.

A Graphical Operator Interface for a Telerobotic Inspection System

NASA Technical Reports Server (NTRS)

Kim, W. S.; Tso, K. S.; Hayati, S.

1993-01-01

Operator interface has recently emerged as an important element for efficient and safe operatorinteractions with the telerobotic system. Recent advances in graphical user interface (GUI) andgraphics/video merging technologies enable development of more efficient, flexible operatorinterfaces. This paper describes an advanced graphical operator interface newly developed for aremote surface inspection system at Jet Propulsion Laboratory. The interface has been designed sothat remote surface inspection can be performed by a single operator with an integrated robot controland image inspection capability. It supports three inspection strategies of teleoperated human visual inspection, human visual inspection with automated scanning, and machine-vision-based automated inspection.

Project Quality Assurance Plan for research and development services provided by Oak Ridge National Laboratory in support of the Westinghouse Materials Company of Ohio Operable Unit 1 Stabilization Development and Treatability Studies Program

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gilliam, T.M.

1991-05-01

This Project Quality Assurance Plan (PQAP) sets forth the quality assurance (QA) requirements that are applied to those elements of the Westinghouse Materials Company of Ohio (WMCO) Operable Unit 1 support at Oak Ridge National Laboratory (ORNL) project that involve research and development (R D) performed at ORNL. This is in compliance with the applicable criteria of 10 CFR Part 50, Appendix B, ANSI/ASME NQA-1, as specified by Department of Energy (DOE) Oak Ridge Operations (ORO) Order 5700.6B. For this application, NQA-1 is the core QA Program requirements document. QA policy, normally found in the requirements document, is contained herein.more » The requirements of this PQAP apply to project activities that affect the quality and reliability/credibility of research, development, and investigative data and documentation. These activities include the functions of attaining quality objectives and assuring that an appropriate QA program scope is established. The scope of activities affecting quality includes organization; personnel training and qualifications; design control; procurement; material handling and storage; operating procedures; testing, surveillance, and auditing; R D investigative activities and documentation; deficiencies; corrective actions; and QA record keeping. 12 figs.« less

Multiscale Multiphysics Developments for Accident Tolerant Fuel Concepts

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gamble, K. A.; Hales, J. D.; Yu, J.

2015-09-01

U 3Si 2 and iron-chromium-aluminum (Fe-Cr-Al) alloys are two of many proposed accident-tolerant fuel concepts for the fuel and cladding, respectively. The behavior of these materials under normal operating and accident reactor conditions is not well known. As part of the Department of Energy’s Accident Tolerant Fuel High Impact Problem program significant work has been conducted to investigate the U 3Si 2 and FeCrAl behavior under reactor conditions. This report presents the multiscale and multiphysics effort completed in fiscal year 2015. The report is split into four major categories including Density Functional Theory Developments, Molecular Dynamics Developments, Mesoscale Developments, andmore » Engineering Scale Developments. The work shown here is a compilation of a collaborative effort between Idaho National Laboratory, Los Alamos National Laboratory, Argonne National Laboratory and Anatech Corp.« less

A New Tool for Environmental and Economic Optimization of Hydropower Operations

NASA Astrophysics Data System (ADS)

Saha, S.; Hayse, J. W.

2012-12-01

As part of a project funded by the U.S. Department of Energy, researchers from Argonne, Oak Ridge, Pacific Northwest, and Sandia National Laboratories collaborated on the development of an integrated toolset to enhance hydropower operational decisions related to economic value and environmental performance. As part of this effort, we developed an analytical approach (Index of River Functionality, IRF) and an associated software tool to evaluate how well discharge regimes achieve ecosystem management goals for hydropower facilities. This approach defines site-specific environmental objectives using relationships between environmental metrics and hydropower-influenced flow characteristics (e.g., discharge or temperature), with consideration given to seasonal timing, duration, and return frequency requirements for the environmental objectives. The IRF approach evaluates the degree to which an operational regime meets each objective and produces a score representing how well that regime meets the overall set of defined objectives. When integrated with other components in the toolset that are used to plan hydropower operations based upon hydrologic forecasts and various constraints on operations, the IRF approach allows an optimal release pattern to be developed based upon tradeoffs between environmental performance and economic value. We tested the toolset prototype to generate a virtual planning operation for a hydropower facility located in the Upper Colorado River basin as a demonstration exercise. We conducted planning as if looking five months into the future using data for the recently concluded 2012 water year. The environmental objectives for this demonstration were related to spawning and nursery habitat for endangered fishes using metrics associated with maintenance of instream habitat and reconnection of the main channel with floodplain wetlands in a representative reach of the river. We also applied existing mandatory operational constraints for the facility during the demonstration. We compared the optimized virtual operation identified by the toolset to actual operations at the facility for the same time period to evaluate implications of the optimized operational regime on power/revenue generation and environmental performance. Argonne National Laboratory's work was part of a larger "Water-Use-Optimization" project supported by the U.S. Department of Energy Office of Energy Efficiency and Renewable Energy, Water Power Program, under Announcement DE-FOA-0000070. The submitted manuscript has been created by UChicago Argonne, LLC, Operator of Argonne National Laboratory ("Argonne"). Argonne, a U.S. Department of Energy Office of Science laboratory, is operated under Contract No. DE-AC02-06CH11357. The U.S. Government retains for itself, and others acting on its behalf, a paid-up nonexclusive, irrevocable worldwide license in said article to reproduce, prepare derivative works, distribute copies to the public, and perform publicly and display publicly, by or on behalf of the Government.

Integration of Weather Data into Airspace and Traffic Operations Simulation (ATOS) for Trajectory- Based Operations Research

NASA Technical Reports Server (NTRS)

Peters, Mark; Boisvert, Ben; Escala, Diego

2009-01-01

Explicit integration of aviation weather forecasts with the National Airspace System (NAS) structure is needed to improve the development and execution of operationally effective weather impact mitigation plans and has become increasingly important due to NAS congestion and associated increases in delay. This article considers several contemporary weather-air traffic management (ATM) integration applications: the use of probabilistic forecasts of visibility at San Francisco, the Route Availability Planning Tool to facilitate departures from the New York airports during thunderstorms, the estimation of en route capacity in convective weather, and the application of mixed-integer optimization techniques to air traffic management when the en route and terminal capacities are varying with time because of convective weather impacts. Our operational experience at San Francisco and New York coupled with very promising initial results of traffic flow optimizations suggests that weather-ATM integrated systems warrant significant research and development investment. However, they will need to be refined through rapid prototyping at facilities with supportive operational users We have discussed key elements of an emerging aviation weather research area: the explicit integration of aviation weather forecasts with NAS structure to improve the effectiveness and timeliness of weather impact mitigation plans. Our insights are based on operational experiences with Lincoln Laboratory-developed integrated weather sensing and processing systems, and derivative early prototypes of explicit ATM decision support tools such as the RAPT in New York City. The technical components of this effort involve improving meteorological forecast skill, tailoring the forecast outputs to the problem of estimating airspace impacts, developing models to quantify airspace impacts, and prototyping automated tools that assist in the development of objective broad-area ATM strategies, given probabilistic weather forecasts. Lincoln Laboratory studies and prototype demonstrations in this area are helping to define the weather-assimilated decision-making system that is envisioned as a key capability for the multi-agency Next Generation Air Transportation System [1]. The Laboratory's work in this area has involved continuing, operations-based evolution of both weather forecasts and models for weather impacts on the NAS. Our experience has been that the development of usable ATM technologies that address weather impacts must proceed via rapid prototyping at facilities whose users are highly motivated to participate in system evolution.

Implementation of a mentored professional development programme in laboratory leadership and management in the Middle East and North Africa.

PubMed

Perrone, L A; Confer, D; Scott, E; Livingston, L; Bradburn, C; McGee, A; Furtwangler, T; Downer, A; Mokdad, A H; Flandin, J F; Shotorbani, S; Asghar, H; Tolbah, H E; Ahmed, H J; Alwan, A; Martin, R

2017-02-01

Laboratories need leaders who can effectively utilize the laboratories' resources, maximize the laboratories'capacity to detect disease, and advocate for laboratories in a fluctuating health care environment. To address this need, the University of Washington, USA, created the Certificate Program in Laboratory Leadership and Management in partnership with WHO Regional Office for the Eastern Mediterranean, and implemented it with 17 participants and 11 mentors from clinical and public health laboratories in 10 countries (Egypt, Iraq, Jordan, Lebanon, Morocco, Oman, Pakistan, Qatar, Saudi Arabia, and Yemen) in 2014. Designed to teach leadership and management skills to laboratory supervisors, the programme enabled participants to improve laboratory testing quality and operations. The programme was successful overall, with 80% of participants completing it and making impactful changes in their laboratories. This success is encouraging and could serve as a model to further strengthen laboratory capacity in the Region.

NASA Johnson Space Center Biomedical Research Resources

NASA Technical Reports Server (NTRS)

Paloski, W. H.

1999-01-01

Johnson Space Center (JSC) medical sciences laboratories constitute a national resource for support of medical operations and life sciences research enabling a human presence in space. They play a critical role in evaluating, defining, and mitigation the untoward effect of human adaption to space flight. Over the years they have developed the unique facilities and expertise required to perform: biomedical sample analysis and physiological performance tests supporting medical evaluations of space flight crew members and scientific investigations of the operationally relevant medical, physiological, cellular, and biochemical issues associated with human space flight. A general overview of these laboratories is presented in viewgraph form.

KSC-2012-6218

NASA Image and Video Library

2012-11-08

CAPE CANAVERAL, Fla. -- Inside a laboratory in the Engineering Development Laboratory, or EDL, at NASA’s Kennedy Space Center in Florida, research scientist Michael Hogue, in the green plaid shirt, describes several technologies to a group of Society of Physics students. About 800 graduate and undergraduate physics students toured Kennedy facilities. A group of about 40 students toured laboratories in the Operations and Checkout Building and the EDL during their visit. The physics students were in Orlando for the 2012 Quadrennial Physics Congress. Photo credit: NASA/Cory Huston

KSC-2012-6215

NASA Image and Video Library

2012-11-08

CAPE CANAVERAL, Fla. -- Inside a laboratory in the Engineering Development Laboratory, or EDL, at NASA’s Kennedy Space Center in Florida, research physicist Phil Metzger describes lunar excavators and soil processing technologies to a group of Society of Physics students. About 800 graduate and undergraduate physics students toured Kennedy facilities. A group of about 40 students toured laboratories in the Operations and Checkout Building and the EDL during their visit. The physics students were in Orlando for the 2012 Quadrennial Physics Congress. Photo credit: NASA/Cory Huston

KSC-2012-6217

NASA Image and Video Library

2012-11-08

CAPE CANAVERAL, Fla. -- – Inside a laboratory in the Engineering Development Laboratory, or EDL, at NASA’s Kennedy Space Center in Florida, research scientist Michael Johansen, in the blue polo shirt, describes dust mitigation technology to a group of Society of Physics students. About 800 graduate and undergraduate physics students toured Kennedy facilities. A group of about 40 students toured laboratories in the Operations and Checkout Building and the EDL during their visit. The physics students were in Orlando for the 2012 Quadrennial Physics Congress. Photo credit: NASA/Cory Huston

KSC-2012-6216

NASA Image and Video Library

2012-11-08

CAPE CANAVERAL, Fla. -- Inside a laboratory in the Engineering Development Laboratory, or EDL, at NASA’s Kennedy Space Center in Florida, research physicist Phil Metzger describes lunar excavators and soil processing technologies to a group of Society of Physics students. About 800 graduate and undergraduate physics students toured Kennedy facilities. A group of about 40 students toured laboratories in the Operations and Checkout Building and the EDL during their visit. The physics students were in Orlando for the 2012 Quadrennial Physics Congress. Photo credit: NASA/Cory Huston

Battelle's Marine Research Laboratory, Sequim

DOE Office of Scientific and Technical Information (OSTI.GOV)

Becker, C.D.; Strand, J.A.

Scientists at Battelle's Marine Research Laboratory (MRL) in Sequim, Washington study the effect of human activities on marine ecosystems, with emphasis on near shore and estuarine environments. The laboratory provides research and development assistance to industry and government agencies engaged in management of marine technologies, operation of coastal power utilities, protection of the marine environment, and related areas. This paper outlines and discusses the functions of Battelle's MRL, it's history, it's unique features, it's areas of expertise, it's current programs, and it's cooperating agencies.

Laboratory for Computer Science Progress Report 19, 1 July 1981-30 June 1982.

DTIC Science & Technology

1984-05-01

Multiprocessor Architectures 202 4. TRIX Operating System 209 5. VLSI Tools 212 ’SYSTEMATIC PROGRAM DEVELOPMENT, 221 1. Introduction 222 2. Specification...exploring distributed operating systems and the architecture of single-user powerful computers that are interconnected by communication networks. The...to now. In particular, we expect to experiment with languages, operating systems , and applications that establish the feasibility of distributed

Complete Report on the Development of Welding Parameters for Irradiated Materials

DOE Office of Scientific and Technical Information (OSTI.GOV)

Frederick, Greg; Sutton, Benjamin J.; Tatman, Jonathan K.

The advanced welding facility at the Radiochemical Engineering Development Center of Oak Ridge National Laboratory, which was conceived to enable research and development of weld repair techniques for nuclear power plant life extension, is now operational. The development of the facility and its advanced welding capabilities, along with the model materials for initial welding trials, were funded jointly by the U.S. Department of Energy, Office of Nuclear Energy, Light Water Reactor Sustainability Program, the Electric Power Research Institute, Long Term Operations Program and the Welding and Repair Technology Center, with additional support from Oak Ridge National Laboratory. Welding of irradiatedmore » materials was initiated on November 17, 2017, which marked a significant step in the development of the facility and the beginning of extensive welding research and development campaigns on irradiated materials that will eventually produce validated techniques and guidelines for weld repair activities carried out to extend the operational lifetimes of nuclear power plants beyond 60 years. This report summarizes the final steps that were required to complete weld process development, initial irradiated materials welding activities, near-term plans for irradiated materials welding, and plans for post-weld analyses that will be carried out to assess the ability of the advanced welding processes to make repairs on irradiated materials.« less

Los Alamos National Security, LLC Request for Information from industrial entities that desire to commercialize Laboratory-developed Extremely Low Resource Optical Identifier (ELROI) tech

DOE Office of Scientific and Technical Information (OSTI.GOV)

Erickson, Michael Charles

Los Alamos National Security, LLC (LANS) is the manager and operator of the Los Alamos National Laboratory for the U.S. Department of Energy National Nuclear Security Administration under contract DE-AC52-06NA25396. LANS is a mission-centric Federally Funded Research and Development Center focused on solving the most critical national security challenges through science and engineering for both government and private customers.

Solving the AI Planning Plus Scheduling Problem Using Model Checking via Automatic Translation from the Abstract Plan Preparation Language (APPL) to the Symbolic Analysis Laboratory (SAL)

NASA Technical Reports Server (NTRS)

Butler, Ricky W.; Munoz, Cesar A.; Siminiceanu, Radu I.

2007-01-01

This paper describes a translator from a new planning language named the Abstract Plan Preparation Language (APPL) to the Symbolic Analysis Laboratory (SAL) model checker. This translator has been developed in support of the Spacecraft Autonomy for Vehicles and Habitats (SAVH) project sponsored by the Exploration Technology Development Program, which is seeking to mature autonomy technology for the vehicles and operations centers of Project Constellation.

The ideal laboratory information system.

PubMed

Sepulveda, Jorge L; Young, Donald S

2013-08-01

Laboratory information systems (LIS) are critical components of the operation of clinical laboratories. However, the functionalities of LIS have lagged significantly behind the capacities of current hardware and software technologies, while the complexity of the information produced by clinical laboratories has been increasing over time and will soon undergo rapid expansion with the use of new, high-throughput and high-dimensionality laboratory tests. In the broadest sense, LIS are essential to manage the flow of information between health care providers, patients, and laboratories and should be designed to optimize not only laboratory operations but also personalized clinical care. To list suggestions for designing LIS with the goal of optimizing the operation of clinical laboratories while improving clinical care by intelligent management of laboratory information. Literature review, interviews with laboratory users, and personal experience and opinion. Laboratory information systems can improve laboratory operations and improve patient care. Specific suggestions for improving the function of LIS are listed under the following sections: (1) Information Security, (2) Test Ordering, (3) Specimen Collection, Accessioning, and Processing, (4) Analytic Phase, (5) Result Entry and Validation, (6) Result Reporting, (7) Notification Management, (8) Data Mining and Cross-sectional Reports, (9) Method Validation, (10) Quality Management, (11) Administrative and Financial Issues, and (12) Other Operational Issues.

Flexible Control and Interprocess Communication on the Rogue GPS Receiver

NASA Technical Reports Server (NTRS)

Blau, R.

1999-01-01

The Rogue receivers are a series of custom high-accuracy Global Positioning System receivers being developed at NASA's Jet Propulsion Laboratory. This thesis describes two additions to the RogueOS, a custom operation system developed for these recievers.

Remote Systems Experience at the Oak Ridge National Laboratory--A Summary of Lessons Learned

DOE Office of Scientific and Technical Information (OSTI.GOV)

Noakes, Mark W; Burgess, Thomas W; Rowe, John C

2011-01-01

Oak Ridge National Laboratory (ORNL) has a long history in the development of remote systems to support the nuclear environment. ORNL, working in conjunction with Central Research Laboratories, created what is believed to be the first microcomputer-based implementation of dual-arm master-slave remote manipulation. As part of the Consolidated Fuel Reprocessing Program, ORNL developed the dual-arm advanced servomanipulator focusing on remote maintainability for systems exposed to high radiation fields. ORNL also participated in almost all of the various technical areas of the U.S. Department of Energy s Robotics Technology Development Program, while leading the Decontamination and Decommissioning and Tank Waste Retrievalmore » categories. Over the course of this involvement, ORNL has developed a substantial base of working knowledge as to what works when and under what circumstances for many types of remote systems tasks as well as operator interface modes, control bandwidth, and sensing requirements to name a few. By using a select list of manipulator systems that is not meant to be exhaustive, this paper will discuss history and outcome of development, field-testing, deployment, and operations from a lessons learned perspective. The final outcome is a summary paper outlining ORNL experiences and guidelines for transition of developmental remote systems to real-world hazardous environments.« less

Problem-based learning biotechnology courses in chemical engineering.

PubMed

Glatz, Charles E; Gonzalez, Ramon; Huba, Mary E; Mallapragada, Surya K; Narasimhan, Balaji; Reilly, Peter J; Saunders, Kevin P; Shanks, Jacqueline V

2006-01-01

We have developed a series of upper undergraduate/graduate lecture and laboratory courses on biotechnological topics to supplement existing biochemical engineering, bioseparations, and biomedical engineering lecture courses. The laboratory courses are based on problem-based learning techniques, featuring two- and three-person teams, journaling, and performance rubrics for guidance and assessment. Participants initially have found them to be difficult, since they had little experience with problem-based learning. To increase enrollment, we are combining the laboratory courses into 2-credit groupings and allowing students to substitute one of them for the second of our 2-credit chemical engineering unit operations laboratory courses.

Issues for laboratory outreach programs.

PubMed

1994-01-01

As we saw in the last "As We See It," many hospitals have begun outreach programs. We explored why outreach programs are established, the steps needed to develop a program, and the way to establish the proper business culture in a hospital laboratory for running a successful program. In this issue we identify the new skills laboratory managers need to be outreach managers, show how some programs maintain a competitive advantage, and explain some of the effects health-care reform will have on outreach services, as we ask: What are the requirements and issues involved in operating a successful laboratory outreach program?

Reduced Toxicity, High Performance Monopropellant at the U.S. Air Force Research Laboratory

DTIC Science & Technology

2010-04-27

develop reduced toxicity monopropellant formulations to replace spacecraft hydrazine monopropellant. The Air Force Research Laboratory’s (AFRL’s...Public Release, Distribution unlimited REDUCED TOXICITY, HIGH PERFORMANCE MONOPROPELLANT AT THE U.S. AIR FORCE RESEARCH LABORATORY T.W. Hawkins...information, including suggestions for reducing this burden to Department of Defense, Washington Headquarters Services, Directorate for Information Operations

A Study of Gaps in Network Knowledge Synthesis

DTIC Science & Technology

2016-10-14

Lincoln Laboratory MASSACHUSETTS INSTITUTE OF TECHNOLOGY LEXINGTON, MASSACHUSETTS Technical Report 1195 A Study of Gaps in Network...unlimited. This report is the result of studies performed at Lincoln Laboratory, a federally funded research and development center operated...specifically authorized by the U.S. Government may violate any copyrights that exist in this work. A Study of Gaps in Network Knowledge Synthesis

Using the Human Systems Simulation Laboratory at Idaho National Laboratory for Safety Focused Research

DOE Office of Scientific and Technical Information (OSTI.GOV)

Joe, Jeffrey .C; Boring, Ronald L.

Under the United States (U.S.) Department of Energy (DOE) Light Water Reactor Sustainability (LWRS) program, researchers at Idaho National Laboratory (INL) have been using the Human Systems Simulation Laboratory (HSSL) to conduct critical safety focused Human Factors research and development (R&D) for the nuclear industry. The LWRS program has the overall objective to develop the scientific basis to extend existing nuclear power plant (NPP) operating life beyond the current 60-year licensing period and to ensure their long-term reliability, productivity, safety, and security. One focus area for LWRS is the NPP main control room (MCR), because many of the instrumentation andmore » control (I&C) system technologies installed in the MCR, while highly reliable and safe, are now difficult to replace and are therefore limiting the operating life of the NPP. This paper describes how INL researchers use the HSSL to conduct Human Factors R&D on modernizing or upgrading these I&C systems in a step-wise manner, and how the HSSL has addressed a significant gap in how to upgrade systems and technologies that are built to last, and therefore require careful integration of analog and new advanced digital technologies.« less

Crisis action planning and replanning using SIPE-2

NASA Technical Reports Server (NTRS)

Skidmore, Jennifer D.

1993-01-01

Rome Laboratory and DARPA are jointly sponsoring an initiative to develop the next generation of AI planning and scheduling technology focused on military operations planning, especially for crisis situations. SRI International has demonstrated their knowledge-based planning technology in this domain with a system called SOCAP, System for Operations Crisis Action Planning. SOCAP's underlying power comes from SIPE-2, a hierarchical, domain-independent, nonlinear AI planner also developed at SRI. This paper discusses the features of SIPE-2 that made it an ideal choice for military operations planning and which contributed greatly to SOCAP's success.

Development of a Sonar Oil Tanker Cargo Measurement System.

DTIC Science & Technology

1980-08-01

used at any one time is dependent upon the capacity of the stripping system. The operation is conducted to strip at least as fast , if not faster, than...operational mode, measure the average value and variance of the thickness of an oil layer on an intermit - tent sampling basis. Laboratory testing

"Bioneering"--Teaching Biotechnology Entrepreneurship at the Undergraduate Level

ERIC Educational Resources Information Center

Collet, Chris; Wyatt, David

2005-01-01

Purpose - The authors have developed an educational model that operates at the undergraduate level and aims to produce graduates who can comfortably operate in the gulf between the laboratory bench and the commercial marketplace. The purpose of the paper is to describe the course, approaches, activities and initial outcomes of the Bachelor of…

Integration of National Laboratory and Low-Activity Waste Pre-Treatment System Technology Service Providers - 16435

DOE Office of Scientific and Technical Information (OSTI.GOV)

Subramanian, Karthik H.; Thien, Michael G.; Wellman, Dawn M.

The National Laboratories are a critical partner and provide expertise in numerous aspects of the successful execution of the Direct-Feed Low Activity Waste Program. The National Laboratories are maturing the technologies of the Low-Activity Waste Pre-Treatment System (LAWPS) consistent with DOE Order 413.3B “Program and Project Management for the Acquisition of Capital Assets” expectations. The National Laboratories continue to mature waste forms, i.e. glass and secondary waste grout, for formulations and predictions of long-term performance as inputs to performance assessments. The working processes with the National Laboratories have been developed in procurements, communications, and reporting to support the necessary delivery-basedmore » technology support. The relationship continues to evolve from planning and technology development to support of ongoing operations and integration of multiple highly coordinated facilities.« less

Systems integration for the Kennedy Space Center (KSC) Robotics Applications Development Laboratory (RADL)

NASA Technical Reports Server (NTRS)

Davis, V. Leon; Nordeen, Ross

1988-01-01

A laboratory for developing robotics technology for hazardous and repetitive Shuttle and payload processing activities is discussed. An overview of the computer hardware and software responsible for integrating the laboratory systems is given. The center's anthropomorphic robot is placed on a track allowing it to be moved to different stations. Various aspects of the laboratory equipment are described, including industrial robot arm control, smart systems integration, the supervisory computer, programmable process controller, real-time tracking controller, image processing hardware, and control display graphics. Topics of research include: automated loading and unloading of hypergolics for space vehicles and payloads; the use of mobile robotics for security, fire fighting, and hazardous spill operations; nondestructive testing for SRB joint and seal verification; Shuttle Orbiter radiator damage inspection; and Orbiter contour measurements. The possibility of expanding the laboratory in the future is examined.

The Max Rover submersible is tested at the Trident pier, Port Canaveral

NASA Technical Reports Server (NTRS)

1997-01-01

Thomas Lippitt of NASA's Advanced Systems Development (ASD) laboratory observes robotic operations as Chris Nicholson, owner of Deep Sea Systems, and Bill Jones of NASA's ASD laboratory operate the unmanned robotic submersible recovery system, known as Max Rover, during a test of the system at the Trident Pier at Port Canaveral. The submersible is seen in the water with the Diver Operated Plug (DOP). Kennedy Space Center's solid rocket booster (SRB) retrieval team and ASD laboratory staff hope that the new robotic technology will make the process of inserting the plug safer and less strenuous. Currently, scuba divers manually insert the DOP into the aft nozzle of a jettisoned SRB 60 to 70 feet below the surface of the Atlantic Ocean. After the plug is installed, water is pumped out of the booster allowing it to float horizontally. It is then towed back to Hangar AF at Cape Canaveral Air Station for refurbishment. Deep Sea Systems of Falmouth, Mass., built the submersible for NASA.

48 CFR 970.1504-1-3 - Special considerations: Laboratory management and operation.

Code of Federal Regulations, 2010 CFR

2010-10-01

...: Laboratory management and operation. 970.1504-1-3 Section 970.1504-1-3 Federal Acquisition Regulations System DEPARTMENT OF ENERGY AGENCY SUPPLEMENTARY REGULATIONS DOE MANAGEMENT AND OPERATING CONTRACTS Contracting by Negotiation 970.1504-1-3 Special considerations: Laboratory management and operation. (a) For the management...

Marie Curie during ORT4

NASA Technical Reports Server (NTRS)

2003-01-01

Marie Curie rover drives down the rear ramp during Operational Readiness Test (ORT) 4.

Pathfinder, a low-cost Discovery mission, is the first of a new fleet of spacecraft that are planned to explore Mars over thenext ten years. Mars Global Surveyor, already en route, arrives at Mars on September 11 to begin a two year orbital reconnaissance of the planet's composition, topography, and climate. Additional orbiters and landers will follow every 26 months.

The Jet Propulsion Laboratory, Pasadena, CA, developed and manages the Mars Pathfinder mission for NASA's Office of Space Science, Washington, D.C. JPL is an operating division of the California Institute of Technology (Caltech). The Imager for Mars Pathfinder (IMP) was developed by the University of Arizona Lunar and Planetary Laboratory under contract to JPL. Peter Smith is the Principal Investigator.

Computer simulation of on-orbit manned maneuvering unit operations

NASA Technical Reports Server (NTRS)

Stuart, G. M.; Garcia, K. D.

1986-01-01

Simulation of spacecraft on-orbit operations is discussed in reference to Martin Marietta's Space Operations Simulation laboratory's use of computer software models to drive a six-degree-of-freedom moving base carriage and two target gimbal systems. In particular, key simulation issues and related computer software models associated with providing real-time, man-in-the-loop simulations of the Manned Maneuvering Unit (MMU) are addressed with special attention given to how effectively these models and motion systems simulate the MMU's actual on-orbit operations. The weightless effects of the space environment require the development of entirely new devices for locomotion. Since the access to space is very limited, it is necessary to design, build, and test these new devices within the physical constraints of earth using simulators. The simulation method that is discussed here is the technique of using computer software models to drive a Moving Base Carriage (MBC) that is capable of providing simultaneous six-degree-of-freedom motions. This method, utilized at Martin Marietta's Space Operations Simulation (SOS) laboratory, provides the ability to simulate the operation of manned spacecraft, provides the pilot with proper three-dimensional visual cues, and allows training of on-orbit operations. The purpose here is to discuss significant MMU simulation issues, the related models that were developed in response to these issues and how effectively these models simulate the MMU's actual on-orbiter operations.

Life sciences payload definition and integration study. Volume 4: Appendix, costs, and data management requirements of the dedicated 30-day laboratory. [carry-on laboratory for Spacelab

NASA Technical Reports Server (NTRS)

1974-01-01

The results of the updated 30-day life sciences dedicated laboratory scheduling and costing activities are documented, and the 'low cost' methodology used to establish individual equipment item costs is explained in terms of its allowances for equipment that is commerical off-the-shelf, modified commercial, and laboratory prototype; a method which significantly lowers program costs. The costs generated include estimates for non-recurring development, recurring production, and recurring operations costs. A cost for a biomedical emphasis laboratory and a Delta cost to provide a bioscience and technology laboratory were also generated. All cost reported are commensurate with the design and schedule definitions available.

List of DOE radioisotope customers with summary of radioisotope shipments, FY 1979

DOE Office of Scientific and Technical Information (OSTI.GOV)

Burlison, J.S.

1980-06-01

The fifteenth edition of the radioisotope customer list was prepared at the request of the Division of Financial Services, Office of the Assistant Secretary for Environment, Department of Energy (DOE). This document lists DOE's radioisotope production and distribution activities by its facilities at Argonne National Laboratory; Pacific Northwest Laboratory; Brookhaven National Laboratory; Hanford Engineering Development Laboratory; Idaho Operations Office; Los Alamos Scientific Laboratory; Mound Facility; Oak Ridge National Laboratory; Rocky Flats Area Office; Savannah River Laboratory; and UNC Nuclear Industries, Inc. The information is divided into five sections: Isotope suppliers, facility, contracts and isotopes or services supplied; alphabetical list ofmore » customers, and isotopes purchased; alphabetical list of isotopes cross-referenced to customer numbers; geographical location of radioisotope customers; and radioisotope sales and transfers-FY 1979.« less

List of DOE radioisotope customers with summary of radioisotope shipments, FY 1981

DOE Office of Scientific and Technical Information (OSTI.GOV)

Burlison, J.S.

1982-09-01

The seventeenth edition of the radioisotope customer list was prepared at the request of the Office of Health and Environmental Research, Office of Energy Research, Department of Energy (DOE). This document lists DOE's radioisotope production and distribution activities by its facilities at Argonne National Laboratory: Pacific Northwest Laboratory; Brookhaven National Laboratory; Hanford Engineering Development Laboratory; Idaho Operations Office; Los Alamos Scientific Laboratory; Mound Facility; Oak Ridge National Laboratory; Savannah River Laboratory; and UNC Nuclear Industries, Inc. The information is divided into five sections: (1) isotope suppliers, facility, contracts and isotopes or services supplied; (2) alphabetical list of customers, and isotopesmore » purchased; (3) alphabetical list of isotopes cross-referenced to customer numbers; (4) geographical location of radioisotope customers; and (5) radioisotope sales and transfers-FY 1980.« less

Laboratory automation: trajectory, technology, and tactics.

PubMed

Markin, R S; Whalen, S A

2000-05-01

Laboratory automation is in its infancy, following a path parallel to the development of laboratory information systems in the late 1970s and early 1980s. Changes on the horizon in healthcare and clinical laboratory service that affect the delivery of laboratory results include the increasing age of the population in North America, the implementation of the Balanced Budget Act (1997), and the creation of disease management companies. Major technology drivers include outcomes optimization and phenotypically targeted drugs. Constant cost pressures in the clinical laboratory have forced diagnostic manufacturers into less than optimal profitability states. Laboratory automation can be a tool for the improvement of laboratory services and may decrease costs. The key to improvement of laboratory services is implementation of the correct automation technology. The design of this technology should be driven by required functionality. Automation design issues should be centered on the understanding of the laboratory and its relationship to healthcare delivery and the business and operational processes in the clinical laboratory. Automation design philosophy has evolved from a hardware-based approach to a software-based approach. Process control software to support repeat testing, reflex testing, and transportation management, and overall computer-integrated manufacturing approaches to laboratory automation implementation are rapidly expanding areas. It is clear that hardware and software are functionally interdependent and that the interface between the laboratory automation system and the laboratory information system is a key component. The cost-effectiveness of automation solutions suggested by vendors, however, has been difficult to evaluate because the number of automation installations are few and the precision with which operational data have been collected to determine payback is suboptimal. The trend in automation has moved from total laboratory automation to a modular approach, from a hardware-driven system to process control, from a one-of-a-kind novelty toward a standardized product, and from an in vitro diagnostics novelty to a marketing tool. Multiple vendors are present in the marketplace, many of whom are in vitro diagnostics manufacturers providing an automation solution coupled with their instruments, whereas others are focused automation companies. Automation technology continues to advance, acceptance continues to climb, and payback and cost justification methods are developing.

[Effects of the ISO 15189 accreditation on Nagoya University Hospital].

PubMed

Yoshiko, Kenichi

2012-07-01

The Department of Clinical Laboratory, Nagoya University Hospital acquired ISO 15189 accreditation in November, 2009. The operation of our Quality Management System (QMS) was first surveyed in October, 2010. In this paper, we reported the activity for the preparation and operation of our QMS and the effects of ISO 15189 accreditation. We investigated the changes in the number and content on nonconformities, incident reports and complaints before and after accreditation as indicators to evaluate the effect of ISO 15189 accreditation. Post accreditation, the number of nonconformities and incident reports decreased, seeming to show an improvement of quality of the laboratory activity; however, the number of complaints increased. We identified the increase of complaints at the phlebotomy station. There had been some problems with blood sampling in the past, but it seemed that staff had a high level of concern regarding these problems at the phlebotomy station and took appropriate measures to resolve the complaints. We confirmed that the ISO 15189 accreditation was instrumental in the improvements of the safety and efficiency on laboratory works. However there was a problem that increase of overtime works to operate the QMS. We deal with development of a laboratory management system using IT recourses to solve the problem.

A Comprehensive Laboratory Animal Facility Pandemic Response Plan

PubMed Central

Roble, Gordon S; Lingenhol, Naomi M; Baker, Bryan; Wilkerson, Amy; Tolwani, Ravi J

2010-01-01

The potential of a severe influenza pandemic necessitates the development of an organized, rational plan for continued laboratory animal facility operation without compromise of the welfare of animals. A comprehensive laboratory animal program pandemic response plan was integrated into a university-wide plan. Preparation involved input from all levels of organizational hierarchy including the IACUC. Many contingencies and operational scenarios were considered based on the severity and duration of the influenza pandemic. Trigger points for systematic action steps were based on the World Health Organization's phase alert criteria. One extreme scenario requires hibernation of research operations and maintenance of reduced numbers of laboratory animal colonies for a period of up to 6 mo. This plan includes active recruitment and cross-training of volunteers for essential personnel positions, protective measures for employee and family health, logistical arrangements for delivery and storage of food and bedding, the removal of waste, and the potential for euthanasia. Strategies such as encouraging and subsidizing cryopreservation of unique strains were undertaken to protect valuable research assets and intellectual property. Elements of this plan were put into practice after escalation of the pandemic alerts due to influenza A (H1N1) in April 2009. PMID:20858365

Development and operation of a quality assurance system for deviations from standard operating procedures in a clinical cell therapy laboratory.

PubMed

McKenna, D; Kadidlo, D; Sumstad, D; McCullough, J

2003-01-01

Errors and accidents, or deviations from standard operating procedures, other policy, or regulations must be documented and reviewed, with corrective actions taken to assure quality performance in a cellular therapy laboratory. Though expectations and guidance for deviation management exist, a description of the framework for the development of such a program is lacking in the literature. Here we describe our deviation management program, which uses a Microsoft Access database and Microsoft Excel to analyze deviations and notable events, facilitating quality assurance (QA) functions and ongoing process improvement. Data is stored in a Microsoft Access database with an assignment to one of six deviation type categories. Deviation events are evaluated for potential impact on patient and product, and impact scores for each are determined using a 0- 4 grading scale. An immediate investigation occurs, and corrective actions are taken to prevent future similar events from taking place. Additionally, deviation data is collectively analyzed on a quarterly basis using Microsoft Excel, to identify recurring events or developing trends. Between January 1, 2001 and December 31, 2001 over 2500 products were processed at our laboratory. During this time period, 335 deviations and notable events occurred, affecting 385 products and/or patients. Deviations within the 'technical error' category were most common (37%). Thirteen percent of deviations had a patient and/or a product impact score > or = 2, a score indicating, at a minimum, potentially affected patient outcome or moderate effect upon product quality. Real-time analysis and quarterly review of deviations using our deviation management program allows for identification and correction of deviations. Monitoring of deviation trends allows for process improvement and overall successful functioning of the QA program in the cell therapy laboratory. Our deviation management program could serve as a model for other laboratories in need of such a program.

DOE Office of Scientific and Technical Information (OSTI.GOV)

None, None

The Laboratory Directed Research and Development (LDRD) program at Oak Ridge National Laboratory (ORNL) reports its status to the U.S. Department of Energy (DOE) in March of each year. The program operates under the authority of DOE Order 413.2B, “Laboratory Directed Research and Development” (April 19, 2006), which establishes DOE’s requirements for the program while providing the Laboratory Director broad flexibility for program implementation. LDRD funds are obtained through a charge to all Laboratory programs. This report includes summaries of all ORNL LDRD research activities supported during FY 2011. The associated FY 2011 ORNL LDRD Self-Assessment (ORNL/PPA-2012/2) provides financial datamore » and an internal evaluation of the program’s management process.« less

DOE Office of Scientific and Technical Information (OSTI.GOV)

None, None

The Laboratory Directed Research and Development (LDRD) program at Oak Ridge National Laboratory (ORNL) reports its status to the U.S. Department of Energy (DOE) in March of each year. The program operates under the authority of DOE Order 413.2B, “Laboratory Directed Research and Development” (April 19, 2006), which establishes DOE’s requirements for the program while providing the Laboratory Director broad flexibility for program implementation. LDRD funds are obtained through a charge to all Laboratory programs. This report includes summaries of all ORNL LDRD research activities supported during FY 2010. The associated FY 2010 ORNL LDRD Self-Assessment (ORNL/PPA-2011/2) provides financial datamore » and an internal evaluation of the program’s management process.« less

Beneficial Reuse of Produced and Flowback Water

EPA Pesticide Factsheets

Water reuse and recycling is a significant issue in the development of oil and gas shale plays in the United StatesDrilling operations – 60,000 to 650,000 gallons per wellHydraulic fracturing operations – 3 million to 5 million gallons per wellDefinition of produced water and flowback waterInteractions of water quality constituents as they relate to water reuse and recyclingTesting criteria in the laboratory and field operations

The Early Development of Satellite Characterization Capabilities at the Air Force Laboratories

NASA Astrophysics Data System (ADS)

Lambert, J.; Kissell, K.

This presentation overviews the development of optical Space Object Identification (SOI) techniques at the Air Force laboratories during the two-decade "pre-operational" period prior to 1980 when the Groundbased Electro-Optical Deep Space Surveillance (GEODSS) sensors were deployed. Beginning with the launch of Sputnik in 1957, the United States Air Force has actively pursued the development and application of optical sensor technology for the detection, tracking, and characterization of artificial satellites. Until the mid-1980s, these activities were primarily conducted within Air Force research and development laboratories which supplied data to the operational components on a contributing basis. This presentation traces the early evolution of the optical space surveillance technologies from the early experimental sensors that led to the current generation of operationally deployed and research systems. The contributions of the participating Air Force organizations and facilities will be reviewed with special emphasis on the development of technologies for the characterization of spacecraft using optical signatures and imagery. The presentation will include descriptions and photographs of the early facilities and instrumentation, and examples of the SOI collection and analysis techniques employed. In this early period, computer support was limited so all aspects of space surveillance relied heavily on manual interaction. Many military, government, educational, and contractor agencies supported the development of instrumentation and analysis techniques. This overview focuses mainly on the role played by Air Force System Command and Office of Aerospace Research, and the closely related activities at the Department of Defense Advanced Research Projects Agency. The omission of other agencies from this review reflects the limitations of this presentation, not the significance of their contributions.

Life sciences payload definition and integration study. Volume 1: Executive summary. [carry-on laboratory for Spacelab

NASA Technical Reports Server (NTRS)

1974-01-01

The definition and integration tasks involved in the development of design concepts for a carry-on laboratory (COL), to be compatible with Spacelab operations, were divided into the following study areas: (1) identification of research and equipment requirements of the COL; (2) development of a number of conceptual layouts for COL based on the defined research of final conceptual designs; and (4) development of COL planning information for definition of COL/Spacelab interface data, cost data, and program cost schedules, including design drawings of a selected COL to permit fabrication of a functional breadboard.

Recent Developments at the Accelerator Laboratory in Jyvaeskylae

DOE Office of Scientific and Technical Information (OSTI.GOV)

Trzaska, Wladyslaw Henryk

Recent developments at the Accelerator Laboratory in Jyvaeskylae are described. In addition to the existing K = 130 a new cyclotron has been added. It is capable of producing of high current proton and deuteron beams at 30 and 15 MeV correspondingly. It should be fully operational in 2010. A new development in Jyvaeskylae is the growing commitment to astroparticle physics. Jyvaeskylae took the main scientific responsibility for a new cosmic-ray experiment EMMA and has joined the LAGUNA project working on the design of the next generation of very large volume detectors for underground observatories.

Operational benefits from the terminal configured vehicle

NASA Technical Reports Server (NTRS)

Reeder, J. P.; Schmitz, R. A.; Clark, L. V.

1979-01-01

The NASA Terminal Configured Vehicle is a flying laboratory used to conduct research and development on improved airborne systems (including avionics) and operational flight procedures, with particular emphasis on utilization in the terminal area environment. The objectives of this technology development activity, focused on conventional transport aircraft, are to develop and demonstrate improvements which can lead to increased airport and runway capacity, increased air traffic controller productivity, energy efficient terminal area operations, reduced weather minima with safety, and reduced community noise by use of appropriate procedures. This paper discusses some early results of this activity in addition to defining present efforts and future research plans.

Synchronous in-field application of life-detection techniques in planetary analog missions

NASA Astrophysics Data System (ADS)

Amador, Elena S.; Cable, Morgan L.; Chaudry, Nosheen; Cullen, Thomas; Gentry, Diana; Jacobsen, Malene B.; Murukesan, Gayathri; Schwieterman, Edward W.; Stevens, Adam H.; Stockton, Amanda; Yin, Chang; Cullen, David C.; Geppert, Wolf

2015-02-01

Field expeditions that simulate the operations of robotic planetary exploration missions at analog sites on Earth can help establish best practices and are therefore a positive contribution to the planetary exploration community. There are many sites in Iceland that possess heritage as planetary exploration analog locations and whose environmental extremes make them suitable for simulating scientific sampling and robotic operations. We conducted a planetary exploration analog mission at two recent lava fields in Iceland, Fimmvörðuháls (2010) and Eldfell (1973), using a specially developed field laboratory. We tested the utility of in-field site sampling down selection and tiered analysis operational capabilities with three life detection and characterization techniques: fluorescence microscopy (FM), adenine-triphosphate (ATP) bioluminescence assay, and quantitative polymerase chain reaction (qPCR) assay. The study made use of multiple cycles of sample collection at multiple distance scales and field laboratory analysis using the synchronous life-detection techniques to heuristically develop the continuing sampling and analysis strategy during the expedition. Here we report the operational lessons learned and provide brief summaries of scientific data. The full scientific data report will follow separately. We found that rapid in-field analysis to determine subsequent sampling decisions is operationally feasible, and that the chosen life detection and characterization techniques are suitable for a terrestrial life-detection field mission. In-field analysis enables the rapid obtainment of scientific data and thus facilitates the collection of the most scientifically relevant samples within a single field expedition, without the need for sample relocation to external laboratories. The operational lessons learned in this study could be applied to future terrestrial field expeditions employing other analytical techniques and to future robotic planetary exploration missions.

A cognitive operating system (COGNOSYS) for JPL's robot, phase 1 report

NASA Technical Reports Server (NTRS)

Mathur, F. P.

1972-01-01

The most important software requirement for any robot development is the COGNitive Operating SYStem (COGNOSYS). This report describes the Stanford University Artificial Intelligence Laboratory's hand eye software system from the point of view of developing a cognitive operating system for JPL's robot. In this, the Phase 1 of the JPL robot COGNOSYS task the installation of a SAIL compiler and a FAIL assembler on Caltech's PDP-10 have been accomplished and guidelines have been prepared for the implementation of a Stanford University type hand eye software system on JPL-Caltech's computing facility. The alternatives offered by using RAND-USC's PDP-10 Tenex operating sytem are also considered.

Reverberation Chamber Uniformity Validation and Radiated Susceptibility Test Procedures for the NASA High Intensity Radiated Fields Laboratory

NASA Technical Reports Server (NTRS)

Koppen, Sandra V.; Nguyen, Truong X.; Mielnik, John J.

2010-01-01

The NASA Langley Research Center's High Intensity Radiated Fields Laboratory has developed a capability based on the RTCA/DO-160F Section 20 guidelines for radiated electromagnetic susceptibility testing in reverberation chambers. Phase 1 of the test procedure utilizes mode-tuned stirrer techniques and E-field probe measurements to validate chamber uniformity, determines chamber loading effects, and defines a radiated susceptibility test process. The test procedure is segmented into numbered operations that are largely software controlled. This document is intended as a laboratory test reference and includes diagrams of test setups, equipment lists, as well as test results and analysis. Phase 2 of development is discussed.

The ESA Laboratory Support Equipment for the ISS.

PubMed

Petrivelli, A

2002-02-01

The Laboratory Support Equipment (LSE) for the International Space Station (ISS) is a suite of general-purpose items that will be available onboard the Station either as self-standing facilities or as equipment that can be used at defined locations. Dedicated to supporting system maintenance and payload operations, some LSE items are derived from commercial equipment, while others have been specifically developed for the ISS. ESA is currently engaged in developing three pressurised facilities and one pointing mechanism that will become part of the LSE complement, namely: the Minus Eighty degree centigrade Laboratory Freezer for the ISS (MELFI), the Microgravity Science Glovebox (MSG), the cryogenic storage and quick/snap freezer system (Cryosystem), the external-payload pointing system (Hexapod).

Space station operations management

NASA Technical Reports Server (NTRS)

Cannon, Kathleen V.

1989-01-01

Space Station Freedom operations management concepts must be responsive to the unique challenges presented by the permanently manned international laboratory. Space Station Freedom will be assembled over a three year period where the operational environment will change as significant capability plateaus are reached. First Element Launch, Man-Tended Capability, and Permanent Manned Capability, represent milestones in operational capability that is increasing toward mature operations capability. Operations management concepts are being developed to accomodate the varying operational capabilities during assembly, as well as the mature operational environment. This paper describes operations management concepts designed to accomodate the uniqueness of Space Station Freedoom, utilizing tools and processes that seek to control operations costs.

Regulatory issues in accreditation of toxicology laboratories.

PubMed

Bissell, Michael G

2012-09-01

Clinical toxicology laboratories and forensic toxicology laboratories operate in a highly regulated environment. This article outlines major US legal/regulatory issues and requirements relevant to accreditation of toxicology laboratories (state and local regulations are not covered in any depth). The most fundamental regulatory distinction involves the purposes for which the laboratory operates: clinical versus nonclinical. The applicable regulations and the requirements and options for operations depend most basically on this consideration, with clinical toxicology laboratories being directly subject to federal law including mandated options for accreditation and forensic toxicology laboratories being subject to degrees of voluntary or state government–required accreditation.

Development and operation of innovative scum to biodiesel pilot-system for the treatment of floatable wastewater scum.

PubMed

Anderson, Erik; Addy, Min; Chen, Paul; Ruan, Roger

2018-02-01

A novel process was developed for the biorefining of floatable wastewater scum and other waste oils from water treatment facilities into biodiesel and other value-added bio-products. To test the scalability and commercial potential of the technology, a 7000 l/year pilot-scale system was designed and built. Scum from a wastewater treatment facility, located in St. Paul, Mn, was collected and converted into methyl esters (biodiesel) according to the process chemistry. All of the incoming and outgoing process streams were sampled, tested, weighed and recorded to calculate both the process efficiency and product quality. Data from the pilot-scale system operation was compared to laboratory results and the theoretically expected values for each individual unit operation. The biodiesel was tested using a third party laboratory and confirmed it met all of the US EPA's test requirements for commercial-grade biodiesel. Copyright © 2017 Elsevier Ltd. All rights reserved.

Advanced Stirling Convertor Dual Convertor Controller Testing at NASA Glenn Research Center in the Radioisotope Power Systems System Integration Laboratory

NASA Technical Reports Server (NTRS)

Dugala, Gina M.; Taylor, Linda M.; Bell, Mark E.; Dolce, James L.; Fraeman, Martin; Frankford, David P.

2015-01-01

NASA Glenn Research Center developed a nonnuclear representation of a Radioisotope Power System (RPS) consisting of a pair of Advanced Stirling Convertors (ASCs), Dual Convertor Controller (DCC) EMs (engineering models) 2 and 3, and associated support equipment, which were tested in the Radioisotope Power Systems System Integration Laboratory (RSIL). The DCC was designed by the Johns Hopkins University Applied Physics Laboratory (JHU/APL) to actively control a pair of ASCs. The first phase of testing included a Dual Advanced Stirling Convertor Simulator (DASCS), which was developed by JHU/APL and simulates the operation and electrical behavior of a pair of ASCs in real time via a combination of hardware and software. RSIL provides insight into the electrical interactions between a representative radioisotope power generator, its associated control schemes, and realistic electric system loads. The first phase of integration testing included the following spacecraft bus configurations: capacitive, battery, and super-capacitor. A load profile, created based on data from several missions, tested the RPS's and RSIL's ability to maintain operation during load demands above and below the power provided by the RPS. The integration testing also confirmed the DCC's ability to disconnect from the spacecraft when the bus voltage dipped below 22 volts or exceeded 36 volts. Once operation was verified with the DASCS, the tests were repeated with actual operating ASCs. The goal of this integration testing was to verify operation of the DCC when connected to a spacecraft and to verify the functionality of the newly designed RSIL. The results of these tests are presented in this paper.

Compact, Automated, Frequency-Agile Microspectrofluorimeter

NASA Technical Reports Server (NTRS)

Fernandez, Salvador M.; Guignon, Ernest F.

1995-01-01

Compact, reliable, rugged, automated cell-culture and frequency-agile microspectrofluorimetric apparatus developed to perform experiments involving photometric imaging observations of single live cells. In original application, apparatus operates mostly unattended aboard spacecraft; potential terrestrial applications include automated or semiautomated diagnosis of pathological tissues in clinical laboratories, biomedical instrumentation, monitoring of biological process streams, and portable instrumentation for testing biological conditions in various environments. Offers obvious advantages over present laboratory instrumentation.

Naval Research Laboratory Major Facilities 2008

DTIC Science & Technology

2008-10-01

Development Laboratory • Secure Supercomputing Facility • CBD/Tilghman Island IR Field Evaluation Facility • Ultra-Short-Pulse Laser Effects Research...EMI Test Facility • Proximity Operations Testbed GENERAL INFORMATION • Maps EX EC U TI V E D IR EC TO RA TE Code 1100 – Institute for Nanoscience...facility: atomic force microscope (AFM); benchtop transmission electron microscope (TEM); cascade probe station; critical point dryer ; dual beam focused

ASK Magazine. No. 9

NASA Technical Reports Server (NTRS)

Post, Todd (Editor)

2002-01-01

Most of this issue is about ACE (Advanced Composition Explorer). We've collected stories by four members of the ACE management team: Don Margolies, the mission manager from Goddard Space Flight Center; Frandsen, science payloads manager from the Caltech Jet Propulsion Laboratory; Mary Chin, project manager in charge of spacecraft development at the Johns Hopkins Applied Physics Laboratory; and Frank Snow, operations and ground systems manager at Goddard.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tsai, H.; Chen, K.; Liu, Y.

The Packaging Certification Program (PCP) of US Department of Energy (DOE) Environmental Management (EM), Office of Safety Management and Operations (EM-60), has developed a radio frequency identification (RFID) system for the management of nuclear materials. Argonne National Laboratory, a PCP supporting laboratory, and Savi Technology, a Lockheed Martin Company, are collaborating in the development of the RFID system, a process that involves hardware modification (form factor, seal sensor and batteries), software development and irradiation experiments. Savannah River National Laboratory and Argonne will soon field test the active RFID system on Model 9975 drums, which are used for storage and transportationmore » of fissile and radioactive materials. Potential benefits of the RFID system are enhanced safety and security, reduced need for manned surveillance, real time access of status and history data, and overall cost effectiveness.« less

Documentation of operational protocol for the use of MAMA software

DOE Office of Scientific and Technical Information (OSTI.GOV)

Schwartz, Daniel S.

2016-01-21

Image analysis of Scanning Electron Microscope (SEM) micrographs is a complex process that can vary significantly between analysts. The factors causing the variation are numerous, and the purpose of Task 2b is to develop and test a set of protocols designed to minimize variation in image analysis between different analysts and laboratories, specifically using the MAMA software package, Version 2.1. The protocols were designed to be “minimally invasive”, so that expert SEM operators will not be overly constrained in the way they analyze particle samples. The protocols will be tested using a round-robin approach where results from expert SEM usersmore » at Los Alamos National Laboratory, Lawrence Livermore National Laboratory, Pacific Northwest National Laboratory, Savannah River National Laboratory, and the National Institute of Standards and Testing will be compared. The variation of the results will be used to quantify uncertainty in the particle image analysis process. The round-robin exercise will proceed with 3 levels of rigor, each with their own set of protocols, as described below in Tasks 2b.1, 2b.2, and 2b.3. The uncertainty will be developed using NIST standard reference material SRM 1984 “Thermal Spray Powder – Particle Size Distribution, Tungsten Carbide/Cobalt (Acicular)” [Reference 1]. Full details are available in the Certificate of Analysis, posted on the NIST website (http://www.nist.gov/srm/).« less

A whole body counting facility in a remote Enewetak Island setting.

PubMed

Bell, Thomas R; Hickman, David; Yamaguchi, Lance; Jackson, William; Hamilton, Terry

2002-08-01

The U.S. Department of Energy (DOE) has recently implemented a series of strategic initiatives to address long-term radiological surveillance needs at former U.S. test sites in the Marshall Islands. The plan is to engage local atoll communities in developing shared responsibilities for implementing radiation protection programs for resettled and resettling populations. As part of this new initiative, DOE agreed to design and construct a radiological laboratory on Enewetak Island, and help develop the necessary local resources to maintain and operate the facility. This cooperative effort was formalized in August 2000 between the DOE, the Republic of the Marshall Islands (RMI), and the Enewetak/Ujelang Local Atoll Government (EULGOV). The laboratory facility was completed in May 2001. The laboratory incorporates both a permanent whole body counting system to assess internal exposures to 137Cs, and clean living space for people providing 24-h void urine samples. DOE continues to provide on-going technical assistance, training, and data quality review while EULGOV provides manpower and infrastructure development to sustain facility operations on a full-time basis. This paper will detail the special construction, transportation and installation issues in establishing a whole body counting facility in an isolated, harsh environmental setting.

The Gravity Recovery and Interior Laboratory mission

NASA Astrophysics Data System (ADS)

Lehman, D. H.; Hoffman, T. L.; Havens, G. G.

The Gravity Recovery and Interior Laboratory (GRAIL) mission, launched in September 2011, successfully completed its Primary Science Mission in June 2012 and Extended Mission in December 2012. Competitively selected under a NASA Announcement of Opportunity in December 2007, GRAIL is a Discovery Program mission subject to a mandatory project cost cap. The purpose of the mission is to precisely map the gravitational field of the Moon to reveal its internal structure from crust to core, determine its thermal evolution, and extend this knowledge to other planets. The mission used twin spacecraft flying in tandem to provide the gravity map. The GRAIL Flight System, consisting of the spacecraft and payload, was developed based on significant heritage from previous missions such as an experimental U.S. Air Force satellite, the Mars Reconnaissance Orbiter (MRO) mission, and the Gravity Recovery and Climate Experiment (GRACE) mission. The Mission Operations System (MOS) was based on high-heritage multimission operations developed by NASA's Jet Propulsion Laboratory and Lockheed Martin. Both the Flight System and MOS were adapted to meet the unique challenges posed by the GRAIL mission design. This paper summarizes the implementation challenges and accomplishments of getting GRAIL ready for launch. It also discusses the in-flight challenges and experiences of operating two spacecraft, and mission results.

A study of electro-mechanical and infrastructure instrumentation facilities in environmental laboratory.

PubMed

Dhawangale, R M; Kawale, S M; Waghmare, Maya; Pandya, G H; Kondawar, V K

2006-01-01

Environmental laboratories carry out measurement and analysis of a number of physical, chemical and biological parameters. Each parameter requires some sort of instrument for its determination. Providing efficient instrumentation services to various departments of the Institute is an stupendous task. Instrumentation services in the form of installation, operation, repair and maintenanace of electro-mechanical equipment requires an in-depth experience and knowledge of the working, fabrication, design and repair of similar type of instruments so that the need of space, installation pre-requisites, budget constraints, availability of essential spares parts could be assessed. The paper discusses the operation of an environmental instrument repairs and maintenance, and audio-visual facilities. Suggestions for drafting of the proper specifications for procurement of laboratory equipments, such as ovens, furnaces, refrigerators, blowers, audio visual aids, and spares and accessories are given in this paper. The paper also gives the detailed information on various aspects that are needed for checking and testing of the equipment against specification before putting it in operational use. Development of a preventive maintenance program involving QC checks and keeping an inventory of essential spares required are also discussed in this paper. It is felt that such services are essential in providing smooth support to carry out research and development activities of the Institute.

LANDFILLS AS BIOREACTORS: RESEARH AT THE OUTER LOOP LANDFILL, LOUISVILLE, KENTUCKY; FIRST INTERIM REPORT

EPA Science Inventory

Interim report resulting from a cooperative research and development agreement (CRADA) between US EP A's Officeof Research and Development - National Risk Management Research Laboratory and a n ongoing field demonstration
of municipal waste landfills being operated as bioreact...

DEVELOPMENT AND APPLICATION OF METHODS TO ASSESS HUMAN EXPOSURE TO PESTICIDES

EPA Science Inventory

Note: this task is schedule to end September 2003. Two tasks will take its place: method development for emerging pesticides including chiral chemistry applications, and in-house laboratory operations. Field sampling methods are covered under a new task proposed this year.
<...

Proton Radiation Therapy in the Hospital Environment: Conception, Development, and Operation of the Initial Hospital-Based Facility

NASA Astrophysics Data System (ADS)

Slater, James M.; Slater, Jerry D.; Wroe, Andrew J.

The world's first hospital-based proton treatment center opened at Loma Linda University Medical Center in 1990, following two decades of development. Patients' needs were the driving force behind its conception, development, and execution; the primary needs were delivery of effective conformal doses of ionizing radiation and avoidance of normal tissue to the maximum extent possible. The facility includes a proton synchrotron and delivery system developed in collaboration with physicists and engineers at Fermi National Accelerator Laboratory and from other high-energy-physics laboratories worldwide. The system, operated and maintained by Loma Linda personnel, was designed to be safe, reliable, flexible in utilization, efficient in use, and upgradeable to meet demands of changing patient needs and advances in technology. Since the facility opened, nearly 14,000 adults and children have been treated for a wide range of cancers and other diseases. Ongoing research is expanding the applications of proton therapy, while reducing costs.

Flexible software architecture for user-interface and machine control in laboratory automation.

PubMed

Arutunian, E B; Meldrum, D R; Friedman, N A; Moody, S E

1998-10-01

We describe a modular, layered software architecture for automated laboratory instruments. The design consists of a sophisticated user interface, a machine controller and multiple individual hardware subsystems, each interacting through a client-server architecture built entirely on top of open Internet standards. In our implementation, the user-interface components are built as Java applets that are downloaded from a server integrated into the machine controller. The user-interface client can thereby provide laboratory personnel with a familiar environment for experiment design through a standard World Wide Web browser. Data management and security are seamlessly integrated at the machine-controller layer using QNX, a real-time operating system. This layer also controls hardware subsystems through a second client-server interface. This architecture has proven flexible and relatively easy to implement and allows users to operate laboratory automation instruments remotely through an Internet connection. The software architecture was implemented and demonstrated on the Acapella, an automated fluid-sample-processing system that is under development at the University of Washington.

Behavior of U 3Si 2 Fuel and FeCrAl Cladding under Normal Operating and Accident Reactor Conditions

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gamble, Kyle Allan Lawrence; Hales, Jason Dean; Barani, Tommaso

2016-09-01

As part of the Department of Energy's Nuclear Energy Advanced Modeling and Simulation program, an Accident Tolerant Fuel High Impact Problem was initiated at the beginning of fiscal year 2015 to investigate the behavior of \\usi~fuel and iron-chromium-aluminum (FeCrAl) claddings under normal operating and accident reactor conditions. The High Impact Problem was created in response to the United States Department of Energy's renewed interest in accident tolerant materials after the events that occurred at the Fukushima Daiichi Nuclear Power Plant in 2011. The High Impact Problem is a multinational laboratory and university collaborative research effort between Idaho National Laboratory, Losmore » Alamos National Laboratory, Argonne National Laboratory, and the University of Tennessee, Knoxville. This report primarily focuses on the engineering scale research in fiscal year 2016 with brief summaries of the lower length scale developments in the areas of density functional theory, cluster dynamics, rate theory, and phase field being presented.« less

PaR-PaR Laboratory Automation Platform

DOE Office of Scientific and Technical Information (OSTI.GOV)

Linshiz, G; Stawski, N; Poust, S

2013-05-01

Labor-intensive multistep biological tasks, such as the construction and cloning of DNA molecules, are prime candidates for laboratory automation. Flexible and biology-friendly operation of robotic equipment is key to its successful integration in biological laboratories, and the efforts required to operate a robot must be much smaller than the alternative manual lab work. To achieve these goals, a simple high-level biology-friendly robot programming language is needed. We have developed and experimentally validated such a language: Programming a Robot (PaR-PaR). The syntax and compiler for the language are based on computer science principles and a deep understanding of biological workflows. PaR-PaRmore » allows researchers to use liquid-handling robots effectively, enabling experiments that would not have been considered previously. After minimal training, a biologist can independently write complicated protocols for a robot within an hour. Adoption of PaR-PaR as a standard cross-platform language would enable hand-written or software-generated robotic protocols to be shared across laboratories.« less

PaR-PaR laboratory automation platform.

PubMed

Linshiz, Gregory; Stawski, Nina; Poust, Sean; Bi, Changhao; Keasling, Jay D; Hillson, Nathan J

2013-05-17

Labor-intensive multistep biological tasks, such as the construction and cloning of DNA molecules, are prime candidates for laboratory automation. Flexible and biology-friendly operation of robotic equipment is key to its successful integration in biological laboratories, and the efforts required to operate a robot must be much smaller than the alternative manual lab work. To achieve these goals, a simple high-level biology-friendly robot programming language is needed. We have developed and experimentally validated such a language: Programming a Robot (PaR-PaR). The syntax and compiler for the language are based on computer science principles and a deep understanding of biological workflows. PaR-PaR allows researchers to use liquid-handling robots effectively, enabling experiments that would not have been considered previously. After minimal training, a biologist can independently write complicated protocols for a robot within an hour. Adoption of PaR-PaR as a standard cross-platform language would enable hand-written or software-generated robotic protocols to be shared across laboratories.

Gate Set Tomography on a trapped ion qubit

NASA Astrophysics Data System (ADS)

Nielsen, Erik; Blume-Kohout, Robin; Gamble, John; Rundinger, Kenneth; Mizrahi, Jonathan; Sterk, Johathan; Maunz, Peter

2015-03-01

We present enhancements to gate-set tomography (GST), which is a framework in which an entire set of quantum logic gates (including preparation and measurement) can be fully characterized without need for pre-calibrated operations. Our new method, ``extended Linear GST'' (eLGST) uses fast, reliable analysis of structured long gate sequences to deliver tomographic precision at the Heisenberg limit with GST's calibration-free framework. We demonstrate this precision on a trapped-ion qubit, and show significant (orders of magnitude) advantage over both standard process tomography and randomized benchmarking. This work was supported by the Laboratory Directed Research and Development (LDRD) program at Sandia National Laboratories. Sandia is a multiprogram laboratory operated by Sandia Corporation, a Lockheed Martin Company, for the United States Department of Energy's National Nuclear Security Administration under Contract DE-AC04-94AL85000.

Nuclear deformation in the laboratory frame

NASA Astrophysics Data System (ADS)

Gilbreth, C. N.; Alhassid, Y.; Bertsch, G. F.

2018-01-01

We develop a formalism for calculating the distribution of the axial quadrupole operator in the laboratory frame within the rotationally invariant framework of the configuration-interaction shell model. The calculation is carried out using a finite-temperature auxiliary-field quantum Monte Carlo method. We apply this formalism to isotope chains of even-mass samarium and neodymium nuclei and show that the quadrupole distribution provides a model-independent signature of nuclear deformation. Two technical advances are described that greatly facilitate the calculations. The first is to exploit the rotational invariance of the underlying Hamiltonian to reduce the statistical fluctuations in the Monte Carlo calculations. The second is to determine quadruple invariants from the distribution of the axial quadrupole operator in the laboratory frame. This allows us to extract effective values of the intrinsic quadrupole shape parameters without invoking an intrinsic frame or a mean-field approximation.

A modern space simulation facility to accommodate high production acceptance testing

NASA Technical Reports Server (NTRS)

Glover, J. D.

1986-01-01

A space simulation laboratory that supports acceptance testing of spacecraft and associated subsystems at throughput rates as high as nine per year is discussed. The laboratory includes a computer operated 27' by 30' space simulation, a 20' by 20' by 20' thermal cycle chamber and an eight station thermal cycle/thermal vacuum test system. The design philosophy and unique features of each system are discussed. The development of operating procedures, test team requirements, test team integration, and other peripheral activation details are described. A discussion of special accommodations for the efficient utilization of the systems in support of high rate production is presented.

Safety in the Chemical Laboratory: Developing Departmental Safety Procedures.

ERIC Educational Resources Information Center

Renfrew, Malcolm M., Ed.; Palladino, George F.

1980-01-01

Presents rationale and guidelines for development of Safety Standard Operating Procedures (Safety SOP) specific for local conditions. Includes an outline of a Safety SOP developed for a department primarily focused on undergraduate education with a wide variety of expertise from common laborer to PhD with 20 years experience. (Author/JN)

User Guide: How to Use and Operate Virtual Reality Equipment in the Systems Assessment and Usability Laboratory (SAUL) for Conducting Demonstrations

DTIC Science & Technology

2017-08-01

ARL-TN-0839 ● AUG 2017 US Army Research Laboratory User Guide: How to Use and Operate Virtual Reality Equipment in the Systems...ARL-TN-0839 ● AUG 2017 US Army Research Laboratory User Guide: How to Use and Operate Virtual Reality Equipment in the Systems...September 2017 4. TITLE AND SUBTITLE User Guide: How to Use and Operate Virtual Reality Equipment in the Systems Assessment and Usability Laboratory

Marshall Space Flight Center Ground Systems Development and Integration

NASA Technical Reports Server (NTRS)

Wade, Gina

2016-01-01

Ground Systems Development and Integration performs a variety of tasks in support of the Mission Operations Laboratory (MOL) and other Center and Agency projects. These tasks include various systems engineering processes such as performing system requirements development, system architecture design, integration, verification and validation, software development, and sustaining engineering of mission operations systems that has evolved the Huntsville Operations Support Center (HOSC) into a leader in remote operations for current and future NASA space projects. The group is also responsible for developing and managing telemetry and command configuration and calibration databases. Personnel are responsible for maintaining and enhancing their disciplinary skills in the areas of project management, software engineering, software development, software process improvement, telecommunications, networking, and systems management. Domain expertise in the ground systems area is also maintained and includes detailed proficiency in the areas of real-time telemetry systems, command systems, voice, video, data networks, and mission planning systems.

Wernher von Braun

NASA Image and Video Library

1959-03-03

Dr. von Braun, Director of the Development Operations Divisons, and Dr. Debus, Director of the Missile Firing Laboratory; Army Ballistic Missile Agency (ABMA), in the blockhouse during the launch of the Pioneer IV, March 3, 1959.

Earth orbital teleoperator systems evaluation

NASA Technical Reports Server (NTRS)

Shields, N. L., Jr.; Slaughter, P. H.; Brye, R. G.; Henderson, D. E.

1979-01-01

The mechanical extension of the human operator to remote and specialized environments poses a series of complex operational questions. A technical and scientific team was organized to investigate these questions through conducting specific laboratory and analytical studies. The intent of the studies was to determine the human operator requirements for remotely manned systems and to determine the particular effects that various system parameters have on human operator performance. In so doing, certain design criteria based on empirically derived data concerning the ultimate control system, the human operator, were added to the Teleoperator Development Program.

An approach to quality and performance control in a computer-assisted clinical chemistry laboratory.

PubMed Central

Undrill, P E; Frazer, S C

1979-01-01

A locally developed, computer-based clinical chemistry laboratory system has been in operation since 1970. This utilises a Digital Equipment Co Ltd PDP 12 and an interconnected PDP 8/F computer. Details are presented of the performance and quality control techniques incorporated into the system. Laboratory performance is assessed through analysis of results from fixed-level control sera as well as from cumulative sum methods. At a simple level the presentation may be considered purely indicative, while at a more sophisticated level statistical concepts have been introduced to aid the laboratory controller in decision-making processes. PMID:438340

Remote sensing of smokestack emissions using a mobile environmental laboratory

NASA Astrophysics Data System (ADS)

Mosebach, Herbert W.; Eisenmann, T.; Schulz-Spahr, Y.; Neureither, I.; Bittner, Hermann; Rippel, Harald; Schaefer, Klaus; Wehner, Dieter; Haus, Rainer

1993-03-01

A mobile environmental laboratory has been developed. This laboratory consists of a van which is equipped with different environmental sensors. The FT-IR system K300 by Kayser- Threde is the key instrument. With this K300 the van can be used for remote measurements of the gaseous emissions from smoke stacks. In addition the laboratory is equipped with standard ambient air analyzers as well as meteorological sensors. A large battery system ensures current source free operation the whole day. Reloading of the batteries takes only one night. remote measurements with this van were carried out at different power plants. Several pollutants could be analyzed. First results are presented.

Accelerating the development of formal thinking in middle and high school students

NASA Astrophysics Data System (ADS)

Adey, Philip; Shayer, Michael

In an attempt to accelerate the development of formal operations in average young adolescents, intervention lessons relating to all formal schemata were designed in the context of school science courses. Over a period of two years, up to 30 intervention lessons were given by science teachers to their classes in eight schools. Boys who started the program aged 12+ showed a pre-posttest effect size on Piagetian tests of 0.89 SD compared with control classes. In terms of British norms for the development of operational thinking this was a mean change from the 51st to the 74th percentile. Neither the middle school students nor the 12+ girls showed greater gain than the controls. Gains were shown by girls in one 11+ class and in the two 11+ laboratory classes. In the laboratory school students given intervention lessons by the researchers maintained their gains over controls in formal operations at a delayed posttest one year after cessation of the program. There was no effect on tests of science achievement during the intervention. It was argued that the interventions needed to be accompanied by in-service training designed to enable teachers to change their teaching style in line with their students' increased operational thinking capacity.

Remedial Action Report for Operable Units 6-05 and 10-04, Phase III

DOE Office of Scientific and Technical Information (OSTI.GOV)

R. P. Wells

2007-08-15

This Phase III remedial action report addresses the remediation of lead-contaminated soils found at the Security Training Facility STF-02 Gun Range at the Idaho National Laboratory Site. Phase I, consisting of developing and implementing institutional controls at Operble Unit 10-04 sites and developing and implementing Idaho National Laboratory Site-wide plans for both institutional controls and ecological monitoring, was addressed in a previous report. Phase II will remediate sites contaminated with trinitrotoluene and Royal Demolition Explosive. Phase IV will remediate hazards from unexploded ordnance.

Science in 60 – Tabletop Fire Prediction

ScienceCinema

Cary, Lyle

2018-01-16

At the Interagency Fire Center at Los Alamos National Laboratory, experts rely on the state-of-the-art Simtable to help them predict the unpredictable. With algorithms that include camera-based object-tracking and projection developed by the Laboratory, the emergency operations team can simulate a wildland fire spreading across any terrain. The table system, developed and marketed by Simtable, a Santa Fe, N.M., company, takes into account weather, vegetation and fuel conditions. The project also received funding from the LANS Venture Acceleration Fund to improve the user interface.

Science in 60 – Tabletop Fire Prediction

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cary, Lyle

At the Interagency Fire Center at Los Alamos National Laboratory, experts rely on the state-of-the-art Simtable to help them predict the unpredictable. With algorithms that include camera-based object-tracking and projection developed by the Laboratory, the emergency operations team can simulate a wildland fire spreading across any terrain. The table system, developed and marketed by Simtable, a Santa Fe, N.M., company, takes into account weather, vegetation and fuel conditions. The project also received funding from the LANS Venture Acceleration Fund to improve the user interface.

List of DOE radioisotope customers with summary of radioisotope shipments, FY 1980

DOE Office of Scientific and Technical Information (OSTI.GOV)

Burlison, J.S.

1981-08-01

The sixteenth edition of the radioisotope customer list was prepared at the request of the Office of Health and Environmental Research, Office of energy Research, Department of Energy (DOE). This document lists DOE's radioisotope production and distribution activities by its facilities at Argonne National Laboratory; Pacific Northwest Laboratory; Brookhaven National Laboraory; Hanford Engineering Development Laboratory; Idaho Operations Office; Los Alamos Scientific Laboratory; Mound Facility; Oak Ridge National Laboratory; Savannah River Laboratory; and UNC Nuclear Industries, Inc. The information is divided into five sections: (1) isotope suppliers, facility, contracts and isotopes or services supplied; (2) alphabetical list of customers, and isotopesmore » purchased; (3) alphabetical list of isotopes cross-referenced to customer numbers; (4) geographical location of radioisotope customers; and (5) radioisotope sales and transfers-FY 1980.« less

Robot Handcontroller

NASA Technical Reports Server (NTRS)

1992-01-01

The PER-Force robotic handcontroller provides a sense of touch or "feel" to an operator manipulating robots. The force simulation and wide range of motion greatly enhances the efficiency of robotic and computer operations. The handcontroller was developed for the Space Station by Cybernet Systems Corporation under a Small Business Innovation Research (SBIR) contract. Commercial applications include underwater use, underground excavations, research laboratories, hazardous waste handling and in manufacturing operations in which it is unsafe or impractical for humans to work.

Application of fuzzy logic-neural network based reinforcement learning to proximity and docking operations

NASA Technical Reports Server (NTRS)

Jani, Yashvant

1992-01-01

As part of the Research Institute for Computing and Information Systems (RICIS) activity, the reinforcement learning techniques developed at Ames Research Center are being applied to proximity and docking operations using the Shuttle and Solar Max satellite simulation. This activity is carried out in the software technology laboratory utilizing the Orbital Operations Simulator (OOS). This interim report provides the status of the project and outlines the future plans.

Salaries and compensation practices in public health, environmental, and agricultural laboratories: findings from a 2010 national survey.

PubMed

DeBoy, John M; Boulton, Matthew L; Carpenter, David F

2013-01-01

The public health, environmental, and agricultural laboratory (PHEAL) workforce is a key component of the public health infrastructure. The national laboratory workforce faces an ongoing challenge of recruitment and retention of workers often related to pay and other compensation issues. To collect information on laboratory salaries and laboratory compensation practices using a national compensation survey targeting the PHEAL workforce. Seventy-three of 109 (67%) PHEAL directors in the 50 states and District of Columbia collectively employ 3723/4830 (77%) PHEAL employees in the United States. A standardized survey was developed and administered in 2010. Compensation data were compiled by job classification, geographic region, laboratory gross operating budget size, laboratory staff size, and laboratory type. Laboratory staff size ranged from 3 to 327 individuals (mean = 74 and median = 51). Median base salaries were lowest in the Southwest and South and highest in the Mountain and Pacific regions. Mean and median laboratory gross operating budgets for all participating PHEALs were $8 609 238 and $5 671 500, respectively. Extra cash compensation, used by 8 of 60 (13.3%) PHEALs, was more likely to go to a scientist-manager or scientist-supervisor. In 2010, a standardized national compensation survey of technical and scientific public health employees working in 73 PHEALs was effective in collecting previously unavailable data about laboratory salaries, laboratory budgets, and payroll practices. Laboratory salaries varied by geographic region and there was an uneven distribution of extra cash compensation among job classifications. The compensation data collected may be useful in characterizing and improving laboratory salary structures and practices to better support workforce recruitment and retention.

Analytical Chemistry Laboratory. Progress report for FY 1996

DOE Office of Scientific and Technical Information (OSTI.GOV)

Green, D.W.; Boparai, A.S.; Bowers, D.L.

The purpose of this report is to summarize the activities of the Analytical Chemistry Laboratory (ACL) at Argonne National Laboratory (ANL) for Fiscal Year (FY) 1996. This annual report is the thirteenth for the ACL. It describes effort on continuing and new projects and contributions of the ACL staff to various programs at ANL. The ACL operates in the ANL system as a full-cost-recovery service center, but has a mission that includes a complementary research and development component: The Analytical Chemistry Laboratory will provide high-quality, cost-effective chemical analysis and related technical support to solve research problems of our clients --more » Argonne National Laboratory, the Department of Energy, and others -- and will conduct world-class research and development in analytical chemistry and its applications. Because of the diversity of research and development work at ANL, the ACL handles a wide range of analytical chemistry problems. Some routine or standard analyses are done, but the ACL usually works with commercial laboratories if our clients require high-volume, production-type analyses. It is common for ANL programs to generate unique problems that require significant development of methods and adaption of techniques to obtain useful analytical data. Thus, much of the support work done by the ACL is very similar to our applied analytical chemistry research.« less

Basic development of a small balloon-mounted telemetry and its operation system by university students

NASA Astrophysics Data System (ADS)

Yamamoto, Masa-yuki; Kakinami, Yoshihiro; Kono, Hiroki

In Japan, the high altitude balloon for scientific observation has been continuously launched by JAXA. The balloon has a possibility to reach 50 km altitude without tight environmental condition for onboard equipments, operating with a cost lower than sounding rockets, however, development of the large-scale scientific observation balloons by university laboratories is still difficult. Being coupled with recent improvement of semiconductor sensors, laboratory-basis balloon experiments using small weather balloons has been becoming easily in these years. Owing to an advantage of wide land fields in continental regions, the launch of such small balloons has become to be carried out many times especially in continental countries (e.g. Near Space Ventures, Inc., 2013). Although the balloon is very small as its diameter of 6 feet, excluding its extra buoyancy and the weight of the balloon itself, it is expected that about 2 kg loading capacity is remained for payloads to send it up to about 35 km altitude. However, operation of such balloons in Japan is not in general because precise prediction of a landing area of the payload is difficult, thus high-risk situation for balloon releases is remained. In this study, we aim to achieve practical engineering experiments of weather balloons in Japan to be used for scientific observation within university laboratory level as an educational context. Here we report an approach of developing many devices for a small tethered balloon currently in progress. We evaluated an accuracy of altitude measurement by using a laboratory developed altitude data logger system that consists of a GPS-module and a barometric altimeter. Diameter of the balloon was about 1.4 m. Being fulfilled with about 1440 L helium, it produced buoyancy of about 15.7 N. Taking into account of total weight including the mooring equipments, available payload mass becomes to be about 1100 g. Applying an advantage of a 3D printer of FDM (Fused Deposition Modeling) method with a 3DCAD design software, we designed and manufactured a camera-platform type antenna rotator that automatically track the balloon direction based on the received GPS data as a balloon operation system on ground with automatic controlling software for the tracking system. In order to develop a future telemetry system onboard a small weather balloon, we have performed an onboard data logger system. In this presentation, system configuration of the automatic tracking system will be introduced more in detail. The telemetry system onboard the small balloon is currently under development. We have a plan to send the measured GPS coordinates, temperature, pressure, and humidity data detected by the onboard sensors to ground. A monitoring camera, a 3-axes accelerometer, geomagnetic azimuth measurement, and power monitoring were added to the developed data logger system. The acquired data will be stored in an SD card aboard as well as transmitted to the ground. Using a vacuum chamber with a pressure sensors and a constant-temperature reservoir in laboratory, environmental tests were operated. In this presentation, introducing the data obtained through the development of a prototype balloon system, our recent results and problems will be discussed.

Ice pack heat sink subsystem - phase 1, volume 2

NASA Technical Reports Server (NTRS)

Roebelen, G. J., Jr.

1973-01-01

The design, development, and test of a functional laboratory model ice pack heat sink subsystem are discussed. Operating instructions to include mechanical and electrical schematics, maintenance instructions, and equipment specifications are presented.

Exploring the Universe Within

ScienceCinema

John Marburger

2017-12-09

A guided tour of Brookhaven's Relativistic Heavy Ion Collider (RHIC) conducted by past Laboratory Director John Marburger. RHIC is a world-class scientific research facility that began operation in 2000, following 10 years of development and construction.

Spacelab user implementation assessment study (software requirements analysis). Volume 1: Executive study

NASA Technical Reports Server (NTRS)

1976-01-01

The primary objective of this study was to develop an integrated approach for the development, implementation, and utilization of all software that is required to efficiently and cost-effectively support advanced technology laboratory flight and ground operations. It was recognized that certain aspects of the operations would be mandatory computerized services; computerization of other aspects would be optional. Thus, the analyses encompassed not only alternate computer utilization and implementations but trade studies of the programmatic effects of non-computerized versus computerized approaches to the operations. A general overview of the study is presented.

Marie Curie during ORT6

NASA Technical Reports Server (NTRS)

2003-01-01

Marie Curie sits on the lander petal prior to deployment during the pre launch Operations Readiness Test (ORT) 6.

Pathfinder, a low-cost Discovery mission, is the first of a new fleet of spacecraft that are planned to explore Mars over thenext ten years. Mars Global Surveyor, already en route, arrives at Mars on September 11 to begin a two year orbital reconnaissance of the planet's composition, topography, and climate. Additional orbiters and landers will follow every 26 months.

The Jet Propulsion Laboratory, Pasadena, CA, developed and manages the Mars Pathfinder mission for NASA's Office of Space Science, Washington, D.C. JPL is an operating division of the California Institute of Technology (Caltech). The Imager for Mars Pathfinder (IMP) was developed by the University of Arizona Lunar and Planetary Laboratory under contract to JPL. Peter Smith is the Principal Investigator.

Mobile wireless network for the urban environment

NASA Astrophysics Data System (ADS)

Budulas, Peter; Luu, Brian; Gopaul, Richard

2005-05-01

As the Army transforms into the Future Force, particular attention must be paid to operations in Complex and Urban Terrain. Our adversaries increasingly draw us into operations in the urban environment and one can presume that this trend will continue in future battles. In order to ensure that the United States Army maintains battlefield dominance, the Army Research Laboratory (ARL) is developing technology to equip our soldiers for the urban operations of the future. Sophisticated soldier borne systems will extend sensing to the individual soldier, and correspondingly, allow the soldier to establish an accurate picture of their surrounding environment utilizing information from local and remote assets. Robotic platforms will be an integral part of the future combat team. These platforms will augment the team with remote sensing modalities, task execution capabilities, and enhanced communication systems. To effectively utilize the products provided by each of these systems, collected data must be exchanged in real time to all affected entities. Therefore, the Army Research Laboratory is also developing the technology that will be required to support high bandwidth mobile communication in urban environments. This technology incorporates robotic systems that will allow connectivity in areas unreachable by traditional systems. This paper will address some of the issues of providing wireless connectivity in complex and urban terrain. It will further discuss approaches developed by the Army Research Laboratory to integrate communications capabilities into soldier and robotic systems and provide seamless connectivity between the elements of a combat team, and higher echelons.

Counted Sb donors in Si quantum dots

NASA Astrophysics Data System (ADS)

Singh, Meenakshi; Pacheco, Jose; Bielejec, Edward; Perry, Daniel; Ten Eyck, Gregory; Bishop, Nathaniel; Wendt, Joel; Luhman, Dwight; Carroll, Malcolm; Lilly, Michael

2015-03-01

Deterministic control over the location and number of donors is critical for donor spin qubits in semiconductor based quantum computing. We have developed techniques using a focused ion beam and a diode detector integrated next to a silicon MOS single electron transistor to gain such control. With the diode detector operating in linear mode, the numbers of ions implanted have been counted and single ion implants have been detected. Poisson statistics in the number of ions implanted have been observed. Transport measurements performed on samples with counted number of implants have been performed and regular coulomb blockade and charge offsets observed. The capacitances to various gates are found to be in agreement with QCAD simulations for an electrostatically defined dot. This work was performed, in part, at the Center for Integrated Nanotechnologies, a U.S. DOE Office of Basic Energy Sciences user facility. The work was supported by Sandia National Laboratories Directed Research and Development Program. Sandia National Laboratories is a multi-program laboratory operated by Sandia Corporation, a Lockheed-Martin Company, for the U. S. Department of Energy under Contract No. DE-AC04-94AL85000.

Evolution of catalytic RNA in the laboratory

NASA Technical Reports Server (NTRS)

Joyce, Gerald F.

1992-01-01

We are interested in the biochemistry of existing RNA enzymes and in the development of RNA enzymes with novel catalytic function. The focal point of our research program has been the design and operation of a laboratory system for the controlled evolution of catalytic RNA. This system serves as working model of RNA-based life and can be used to explore the catalytic potential of RNA. Evolution requires the integration of three chemical processes: amplification, mutation, and selection. Amplification results in additional copies of the genetic material. Mutation operates at the level of genotype to introduce variability, this variability in turn being expressed as a range of phenotypes. Selection operates at the level of phenotype to reduce variability by excluding those individuals that do not conform to the prevailing fitness criteria. These three processes must be linked so that only the selected individuals are amplified, subject to mutational error, to produce a progeny distribution of mutant individuals. We devised techniques for the amplification, mutation, and selection of catalytic RNA, all of which can be performed rapidly in vitro within a single reaction vessel. We integrated these techniques in such a way that they can be performed iteratively and routinely. This allowed us to conduct evolution experiments in response to artificially-imposed selection constraints. Our objective was to develop novel RNA enzymes by altering the selection constraints in a controlled manner. In this way we were able to expand the catalytic repertoire of RNA. Our long-range objective is to develop an RNA enzyme with RNA replicase activity. If such an enzyme had the ability to produce additional copies of itself, then RNA evolution would operate autonomously and the origin of life will have been realized in the laboratory.

Laboratory and Workplace Assessments of Rivet Bucking Bar Vibration Emissions

PubMed Central

McDowell, Thomas W.; Warren, Christopher; Xu, Xueyan S.; Welcome, Daniel E.; Dong, Ren G.

2016-01-01

Sheet metal workers operating rivet bucking bars are at risk of developing hand and wrist musculoskeletal disorders associated with exposures to hand-transmitted vibrations and forceful exertions required to operate these hand tools. New bucking bar technologies have been introduced in efforts to reduce workplace vibration exposures to these workers. However, the efficacy of these new bucking bar designs has not been well documented. While there are standardized laboratory-based methodologies for assessing the vibration emissions of many types of powered hand tools, no such standard exists for rivet bucking bars. Therefore, this study included the development of a laboratory-based method for assessing bucking bar vibrations which utilizes a simulated riveting task. With this method, this study evaluated three traditional steel bucking bars, three similarly shaped tungsten alloy bars, and three bars featuring spring-dampeners. For comparison the bucking bar vibrations were also assessed during three typical riveting tasks at a large aircraft maintenance facility. The bucking bars were rank-ordered in terms of unweighted and frequency-weighted acceleration measured at the hand-tool interface. The results suggest that the developed laboratory method is a reasonable technique for ranking bucking bar vibration emissions; the lab-based riveting simulations produced similar rankings to the workplace rankings. However, the laboratory-based acceleration averages were considerably lower than the workplace measurements. These observations suggest that the laboratory test results are acceptable for comparing and screening bucking bars, but the laboratory measurements should not be directly used for assessing the risk of workplace bucking bar vibration exposures. The newer bucking bar technologies exhibited significantly reduced vibrations compared to the traditional steel bars. The results of this study, together with other information such as rivet quality, productivity, tool weight, comfort, worker acceptance, and initial cost can be used to make informed bucking bar selections. PMID:25381185

Laboratory and workplace assessments of rivet bucking bar vibration emissions.

PubMed

McDowell, Thomas W; Warren, Christopher; Xu, Xueyan S; Welcome, Daniel E; Dong, Ren G

2015-04-01

Sheet metal workers operating rivet bucking bars are at risk of developing hand and wrist musculoskeletal disorders associated with exposures to hand-transmitted vibrations and forceful exertions required to operate these hand tools. New bucking bar technologies have been introduced in efforts to reduce workplace vibration exposures to these workers. However, the efficacy of these new bucking bar designs has not been well documented. While there are standardized laboratory-based methodologies for assessing the vibration emissions of many types of powered hand tools, no such standard exists for rivet bucking bars. Therefore, this study included the development of a laboratory-based method for assessing bucking bar vibrations which utilizes a simulated riveting task. With this method, this study evaluated three traditional steel bucking bars, three similarly shaped tungsten alloy bars, and three bars featuring spring-dampeners. For comparison the bucking bar vibrations were also assessed during three typical riveting tasks at a large aircraft maintenance facility. The bucking bars were rank-ordered in terms of unweighted and frequency-weighted acceleration measured at the hand-tool interface. The results suggest that the developed laboratory method is a reasonable technique for ranking bucking bar vibration emissions; the lab-based riveting simulations produced similar rankings to the workplace rankings. However, the laboratory-based acceleration averages were considerably lower than the workplace measurements. These observations suggest that the laboratory test results are acceptable for comparing and screening bucking bars, but the laboratory measurements should not be directly used for assessing the risk of workplace bucking bar vibration exposures. The newer bucking bar technologies exhibited significantly reduced vibrations compared to the traditional steel bars. The results of this study, together with other information such as rivet quality, productivity, tool weight, comfort, worker acceptance, and initial cost can be used to make informed bucking bar selections. Published by Oxford University Press on behalf of the British Occupational Hygiene Society 2014.

Driving R&D for the Next Generation Work Truck; NREL (National Renewable Energy Laboratory)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Melendez, M.

2015-03-04

Improvements in medium- and heavy-duty work truck energy efficiency can dramatically reduce the use of petroleum-based fuels and the emissions of greenhouse gases. The National Renewable Energy Laboratory (NREL) is working with industry partners to develop fuel-saving, high-performance vehicle technologies, while examining fleet operational practices that can simulateneously improve fuel economy, decrease emissions, and support bottom-line goals.

Commercialization of Kennedy Space Center Instrumentation Developed to Improve Safety, Reliability, Cost Effectiveness of Space Shuttle Processing, Launch, and Landing

NASA Technical Reports Server (NTRS)

Helms, William R.; Starr, Stanley O.

1997-01-01

Priorities and achievements of the Kennedy Space Center (KSF) Instrumentation Laboratories in improving operational safety and decreasing processing costs associated with the Shuttle vehicle are addressed. Technologies that have been or are in the process of technology transfer are reviewed, and routes by which commercial concerns can obtain licenses to other KSF Instrumentation Laboratory technologies are discussed.

Overview and Status of the Laser Communication Relay Demonstration

NASA Technical Reports Server (NTRS)

Luzhanskiy, E.; Edwards, B.; Israel, D.; Cornwell, D.; Staren, J.; Cummings, N.; Roberts, T.; Patschke, R.

2016-01-01

NASA is presently developing first all optical high data rate satellite relay system, LCRD. To be flown on commercial geosynchronous satellite, it will communicate at DPSK and PPM modulation formats up to 1.244 Gbps. LCRD flight payload is being developed by NASA's Goddard Space Flight Center. The two ground stations, one on Table Mountain in CA, developed by NASA's Jet Propulsion Laboratory and another on Hawaiian island will enable bi-directional relay operation and ground sites diversity experiments. In this paper we will report on the current state of LCRD system development, planned operational scenarios and expected system performance.

2000-hour cyclic endurance test of a laboratory model multipropellant resistojet

NASA Technical Reports Server (NTRS)

Morren, W. Earl; Sovey, James S.

1987-01-01

The technological readiness of a long-life multipropellant resistojet for space station auxiliary propulsion is demonstrated. A laboratory model resistojet made from grain-stabilized platinum served as a test bed to evaluate the design characteristics, fabrication methods, and operating strategies for an engineering model multipropellant resistojet developed under contract by the Rocketdyne Division of Rockwell International and Technion Incorporated. The laboratory model thruster was subjected to a 2000-hr, 2400-thermal-cycle endurance test using carbon dioxide propellant. Maximum thruster temperatures were approximately 1400 C. The post-test analyses of the laboratory model thruster included an investigation of component microstructures. Significant observations from the laboratory model thruster are discussed as they relate to the design of the engineering model thruster.

A 2000-hour cyclic endurance test of a laboratory model multipropellant resistojet

NASA Technical Reports Server (NTRS)

Morren, W. Earl; Sovey, James S.

1987-01-01

The technological readiness of a long-life multipropellant resistojet for space station auxiliary propulsion is demonstrated. A laboratory model resistojet made from grain-stabilized platinum served as a test bed to evaluate the design characteristics, fabrication methods, and operating strategies for an engineering model multipropellant resistojet developed under contract by the Rocketdyne Division of Rockwell International and Technion Incorporated. The laboratory model thruster was subjected to a 2000-hr, 2400-thermal-cycle endurance test using carbon dioxide propellant. Maximum thruster temperatures were approximately 1400 C. The post-test analyses of the laboratory model thruster included an investigation of component microstructures. Significant observations from the laboratory model thruster are discussed as they relate to the design of the engineering model thruster.

Hanford Laboratories Operation monthly activities report, August 1959

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1959-09-15

This is the monthly report for the Hanford Laboratories Operation, August, 1959. Reactor fuels, chemistry, dosimetry, separation processes, reactor technology financial activities, visits, biology operation, physics and instrumentation research, employee relations, and operations research and synthesis operation are discussed.

Hanford Laboratories Operation monthly activities report, September 1961

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1961-10-16

This is the monthly report for the Hanford Laboratories Operation September 1961. Reactor fuels, chemistry, dosimetry, separation processes, reactor technology, financial activities, biology operation, physics and instrumentation research, operations research and synthesis, programming, and radiation protection operation are discussed.

The impact of SLMTA in improving laboratory quality systems in the Caribbean Region.

PubMed

Guevara, Giselle; Gordon, Floris; Irving, Yvette; Whyms, Ismae; Parris, Keith; Beckles, Songee; Maruta, Talkmore; Ndlovu, Nqobile; Albalak, Rachel; Alemnji, George

Past efforts to improve laboratory quality systems and to achieve accreditation for better patient care in the Caribbean Region have been slow. To describe the impact of the Strengthening of Laboratory Management Toward Accreditation (SLMTA) training programme and mentorship amongst five clinical laboratories in the Caribbean after 18 months. Five national reference laboratories from four countries participated in the SLMTA programme that incorporated classroom teaching and implementation of improvement projects. Mentors were assigned to the laboratories to guide trainees on their improvement projects and to assist in the development of Quality Management Systems (QMS). Audits were conducted at baseline, six months, exit (at 12 months) and post-SLMTA (at 18 months) using the Stepwise Laboratory Quality Improvement Process Towards Accreditation (SLIPTA) checklist to measure changes in implementation of the QMS during the period. At the end of each audit, a comprehensive implementation plan was developed in order to address gaps. Baseline audit scores ranged from 19% to 52%, corresponding to 0 stars on the SLIPTA five-star scale. After 18 months, one laboratory reached four stars, two reached three stars and two reached two stars. There was a corresponding decrease in nonconformities and development of over 100 management and technical standard operating procedures in each of the five laboratories. The tremendous improvement in these five Caribbean laboratories shows that SLMTA coupled with mentorship is an effective, user-friendly, flexible and customisable approach to the implementation of laboratory QMS. It is recommended that other laboratories in the region consider using the SLMTA training programme as they engage in quality systems improvement and preparation for accreditation.

GeoLab: A Geological Workstation for Future Missions

NASA Technical Reports Server (NTRS)

Evans, Cynthia; Calaway, Michael; Bell, Mary Sue; Li, Zheng; Tong, Shuo; Zhong, Ye; Dahiwala, Ravi

2014-01-01

The GeoLab glovebox was, until November 2012, fully integrated into NASA's Deep Space Habitat (DSH) Analog Testbed. The conceptual design for GeoLab came from several sources, including current research instruments (Microgravity Science Glovebox) used on the International Space Station, existing Astromaterials Curation Laboratory hardware and clean room procedures, and mission scenarios developed for earlier programs. GeoLab allowed NASA scientists to test science operations related to contained sample examination during simulated exploration missions. The team demonstrated science operations that enhance theThe GeoLab glovebox was, until November 2012, fully integrated into NASA's Deep Space Habitat (DSH) Analog Testbed. The conceptual design for GeoLab came from several sources, including current research instruments (Microgravity Science Glovebox) used on the International Space Station, existing Astromaterials Curation Laboratory hardware and clean room procedures, and mission scenarios developed for earlier programs. GeoLab allowed NASA scientists to test science operations related to contained sample examination during simulated exploration missions. The team demonstrated science operations that enhance the early scientific returns from future missions and ensure that the best samples are selected for Earth return. The facility was also designed to foster the development of instrument technology. Since 2009, when GeoLab design and construction began, the GeoLab team [a group of scientists from the Astromaterials Acquisition and Curation Office within the Astromaterials Research and Exploration Science (ARES) Directorate at JSC] has progressively developed and reconfigured the GeoLab hardware and software interfaces and developed test objectives, which were to 1) determine requirements and strategies for sample handling and prioritization for geological operations on other planetary surfaces, 2) assess the scientific contribution of selective in-situ sample characterization for mission planning, operations, and sample prioritization, 3) evaluate analytical instruments and tools for providing efficient and meaningful data in advance of sample return and 4) identify science operations that leverage human presence with robotic tools. In the first year of tests (2010), GeoLab examined basic glovebox operations performed by one and two crewmembers and science operations performed by a remote science team. The 2010 tests also examined the efficacy of basic sample characterization [descriptions, microscopic imagery, X-ray fluorescence (XRF) analyses] and feedback to the science team. In year 2 (2011), the GeoLab team tested enhanced software and interfaces for the crew and science team (including Web-based and mobile device displays) and demonstrated laboratory configurability with a new diagnostic instrument (the Multispectral Microscopic Imager from the JPL and Arizona State University). In year 3 (2012), the GeoLab team installed and tested a robotic sample manipulator and evaluated robotic-human interfaces for science operations.

Laboratory directed research and development program FY 1999

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hansen, Todd; Levy, Karin

2000-03-08

The Ernest Orlando Lawrence Berkeley National Laboratory (Berkeley Lab or LBNL) is a multi-program national research facility operated by the University of California for the Department of Energy (DOE). As an integral element of DOE's National Laboratory System, Berkeley Lab supports DOE's missions in fundamental science, energy resources, and environmental quality. Berkeley Lab programs advance four distinct goals for DOE and the nation: (1) To perform leading multidisciplinary research in the computing sciences, physical sciences, energy sciences, biosciences, and general sciences in a manner that ensures employee and public safety and protection of the environment. (2) To develop and operatemore » unique national experimental facilities for qualified investigators. (3) To educate and train future generations of scientists and engineers to promote national science and education goals. (4) To transfer knowledge and technological innovations and to foster productive relationships among Berkeley Lab's research programs, universities, and industry in order to promote national economic competitiveness. This is the annual report on Laboratory Directed Research and Development (LDRD) program for FY99.« less

ANNUAL REPORT, JULY 1, 1958

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

1959-02-01

This annual report of Brookhaven National Laboratory describes its program and activities for the fiscal year 1958. The progress and trends of the research program are presented along with a description of the operational, service, and administrative activities of the Laboratory. The scientific and technical details of the many research and development activities are covered more fully in scientific and technical periodicals and in the quarterly scientific progress reports and other scientiflc reports of the Laboratory. A list of all publications for July 1, 1957 to June 30, 1958, is given. Status and progress are given in fields of physics,more » accelerator development, instrumentation, applied mathematics, chemistry, nuclear engineering, biology, and medical research. (For preceding period see BNL-462.) (W.D.M.)« less

Bosch CO2 Reduction System Development

NASA Technical Reports Server (NTRS)

Holmes, R. F.; King, C. D.; Keller, E. E.

1976-01-01

Development of a Bosch process CO2 reduction unit was continued, and, by means of hardware modifications, the performance was substantially improved. Benefits of the hardware upgrading were demonstrated by extensive unit operation and data acquisition in the laboratory. This work was accomplished on a cold seal configuration of the Bosch unit.

Parent Handbook.

ERIC Educational Resources Information Center

Illinois Univ., Urbana. Child Development Lab.

This booklet contains information for parents whose children are enrolled in the Child Development Laboratory (CDL), a university-based preschool and child care program operated by the Department of Human and Community Development on the campus of the University of Illinois. The program provides half-day preschool for 2- to 4-year-old children and…

New seed-cotton reclaimer for high speed roller gins

USDA-ARS?s Scientific Manuscript database

An experimental laboratory prototype reclaimer is being developed by the USDA-ARS in cooperation with Lummus Corporation. The objective of the project is to develop a seed-cotton reclaimer for high speed roller ginning that has a higher operational capacity and reduced seed loss in comparison to cur...

The SLMTA programme: Transforming the laboratory landscape in developing countries

PubMed Central

Maruta, Talkmore; Luman, Elizabeth T.; Nkengasong, John N.

2014-01-01

Background Efficient and reliable laboratory services are essential to effective and well-functioning health systems. Laboratory managers play a critical role in ensuring the quality and timeliness of these services. However, few laboratory management programmes focus on the competencies required for the daily operations of a laboratory in resource-limited settings. This report provides a detailed description of an innovative laboratory management training tool called Strengthening Laboratory Management Toward Accreditation (SLMTA) and highlights some challenges, achievements and lessons learned during the first five years of implementation (2009–2013) in developing countries. Programme SLMTA is a competency-based programme that uses a series of short courses and work-based learning projects to effect immediate and measurable laboratory improvement, while empowering laboratory managers to implement practical quality management systems to ensure better patient care. A SLMTA training programme spans from 12 to 18 months; after each workshop, participants implement improvement projects supported by regular supervisory visits or on-site mentoring. In order to assess strengths, weaknesses and progress made by the laboratory, audits are conducted using the World Health Organization’s Regional Office for Africa (WHO AFRO) Stepwise Laboratory Quality Improvement Process Towards Accreditation (SLIPTA) checklist, which is based on International Organization for Standardization (ISO) 15189 requirements. These internal audits are conducted at the beginning and end of the SLMTA training programme. Conclusion Within five years, SLMTA had been implemented in 617 laboratories in 47 countries, transforming the laboratory landscape in developing countries. To our knowledge, SLMTA is the first programme that makes an explicit connection between the performance of specific management behaviours and routines and ISO 15189 requirements. Because of this close relationship, SLMTA is uniquely positioned to help laboratories seek accreditation to ISO 15189. PMID:26752335

An Expert System For Tuning Particle-Beam Accelerators

NASA Astrophysics Data System (ADS)

Lager, Darrel L.; Brand, Hal R.; Maurer, William J.; Searfus, Robert M.; Hernandez, Jose E.

1989-03-01

We have developed a proof-of-concept prototype of an expert system for tuning particle beam accelerators. It is designed to function as an intelligent assistant for an operator. In its present form it implements the strategies and reasoning followed by the operator for steering through the beam transport section of the Advanced Test Accelerator at Lawrence Livermore Laboratory's Site 300. The system is implemented in the language LISP using the Artificial Intelligence concepts of frames, daemons, and a representation we developed called a Monitored Decision Script.

Development of Carbon-14 Waste Destruction and Recovery System Using AC Plasma Torch Technology Final Report CRADA No. TC02108.0

DOE Office of Scientific and Technical Information (OSTI.GOV)

Althouse, P.; McKannay, R. H.

This was a collaborative effort between Lawrence Livermore National Security, LLC as manager and operator of Lawrence Livermore National Laboratory (LLNL) and ISOFLEX USA (ISOFLEX), to 1) develop and test a prototype waste destruction system ("System") using AC plasma torch technology to break down and drastically reduce the volume of Carbon-14 (C-14) contaminated medical laboratory wastes while satisfying all environmental regulations, and 2) develop and demonstrate methods for recovering 99%+ of the carbon including the C-14 allowing for possible re-use as a tagging and labeling tool in the biomedical industry.

Space Station laboratory module power loading analysis

NASA Astrophysics Data System (ADS)

Fu, S. J.

1994-07-01

The electrical power system of Space Station Freedom is an isolated electrical power generation and distribution network designed to meet the demands of a large number of electrical loads. An algorithm is developed to determine the power bus loading status under normal operating conditions to ensure the supply meets demand. The probabilities of power availability for payload operations (experiments) are also derived.

The Operation of a Specialized Scientific Information and Data Analysis Center With Computer Base and Associated Communications Network.

ERIC Educational Resources Information Center

Cottrell, William B.; And Others

The Nuclear Safety Information Center (NSIC) is a highly sophisticated scientific information center operated at Oak Ridge National Laboratory (ORNL) for the U.S. Atomic Energy Commission. Its information file, which consists of both data and bibliographic information, is computer stored and numerous programs have been developed to facilitate the…

A new 2 Kelvin Superconducting Half-Wave Cavity Cryomodule for PIP-II

NASA Astrophysics Data System (ADS)

Conway, Z. A.; Barcikowski, A.; Cherry, G. L.; Fischer, R. L.; Gerbick, S. M.; Jansma, W. G.; Kedzie, M. J.; Kelly, M. P.; Kim, S.-h.; Lebedev, V. A.; MacDonald, S. W. T.; Nicol, T. H.; Ostroumov, P. N.; Reid, T. C.; Shepard, K. W.; White, M. J.

2015-12-01

Argonne National Laboratory has developed and is implementing a novel 2 K superconducting cavity cryomodule operating at 162.5 MHz. This cryomodule is designed for the acceleration of 2 mA H-/proton beams from 2.1 to 10 MeV as part of the Fermilab Proton Improvement Project-II (PIP-II). This work is an evolution of techniques recently implemented in two previous heavy-ion accelerator cryomodules now operating at Argonne National Laboratory. The 2 K cryomodule is comprised of 8 half-wave cavities operated in the continuous wave mode with 8 superconducting magnets, one in front of each cavity. All of the solenoids and cavities operate off of a single gravity fed 2 K helium cryogenic system expected to provide up to 50 W of 2 K cooling. Here we review the mechanical design of the cavities and cryomodule which were developed using methods similar to those required in the ASME Boiler and Pressure Vessel Code. This will include an overview of the cryomodule layout, the alignment of the accelerator components via modifications of the cryomodule vacuum vessel and provide a status report on the cryomodule assembly.

Air Force Research Laboratory Spacecraft Cryocooler Endurance Evaluation Facility Closing Report

NASA Astrophysics Data System (ADS)

Armstrong, J.; Martin, K. W.; Fraser, T.

2015-12-01

The Air Force Research Laboratory (AFRL) Spacecraft Component Thermal Research Group has been devoted to evaluating lifetime performance of space cryocooler technology for over twenty years. Long-life data is essential for confirming design lifetimes for space cryocoolers. Continuous operation in a simulated space environment is the only accepted method to test for degradation. AFRL has provided raw data and detailed evaluations to cryocooler developers for advancing the technology, correcting discovered deficiencies, and improving cryocooler designs. At AFRL, units of varying design and refrigeration cycles were instrumented in state-of-the-art experiment stands to provide spacelike conditions and were equipped with software data acquisition to track critical cryocooler operating parameters. This data allowed an assessment of the technology's ability to meet the desired lifetime and documented any long-term changes in performance. This paper will outline a final report of the various flight cryocoolers tested in our laboratory. The data summarized includes the seven cryocoolers tested during 2014-2015. These seven coolers have a combined total of 433,326 hours (49.5 years) of operation.

A monitor for the laboratory evaluation of control integrity in digital control systems operating in harsh electromagnetic environments

NASA Technical Reports Server (NTRS)

Belcastro, Celeste M.; Fischl, Robert; Kam, Moshe

1992-01-01

This paper presents a strategy for dynamically monitoring digital controllers in the laboratory for susceptibility to electromagnetic disturbances that compromise control integrity. The integrity of digital control systems operating in harsh electromagnetic environments can be compromised by upsets caused by induced transient electrical signals. Digital system upset is a functional error mode that involves no component damage, can occur simultaneously in all channels of a redundant control computer, and is software dependent. The motivation for this work is the need to develop tools and techniques that can be used in the laboratory to validate and/or certify critical aircraft controllers operating in electromagnetically adverse environments that result from lightning, high-intensity radiated fields (HIRF), and nuclear electromagnetic pulses (NEMP). The detection strategy presented in this paper provides dynamic monitoring of a given control computer for degraded functional integrity resulting from redundancy management errors, control calculation errors, and control correctness/effectiveness errors. In particular, this paper discusses the use of Kalman filtering, data fusion, and statistical decision theory in monitoring a given digital controller for control calculation errors.

Ranking protective coatings: Laboratory vs. field experience

NASA Astrophysics Data System (ADS)

Conner, Jeffrey A.; Connor, William B.

1994-12-01

Environmentally protective coatings are used on a wide range of gas turbine components for survival in the harsh operating conditions of engines. A host of coatings are commercially available to protect hot-section components, ranging from simple aluminides to designer metallic overlays and ceramic thermal barrier coatings. A variety of coating-application processes are available, and they range from simple pack cementation processing to complex physical vapor deposition, which requires multimillion dollar facilities. Detailed databases are available for most coatings and coating/process combinations for a range of laboratory tests. Still, the analysis of components actually used in engines often yields surprises when compared against predicted coating behavior from laboratory testing. This paper highlights recent work to develop new laboratory tests that better simulate engine environments. Comparison of in-flight coating performance as well as industrial and factory engine testing on a range of hardware is presented along with laboratory predictions from standard testing and from recently developed cyclic burner-rig testing.

Hanford Laboratories monthly activities report, March 1964

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1964-04-15

The monthly report for the Hanford Laboratories Operation, March 1964. Reactor fuels, chemistry, dosimetry, separation processes, reactor technology, financial activities, biology operation, and physics and instrumentation research, and applied mathematics operation, and programming operations are discussed.

Medical operations: Crew surgeon's report. [in Skylab simulation test

NASA Technical Reports Server (NTRS)

Ross, C. E.

1973-01-01

To assure the safety and well being of the Skylab environment simulation crewmembers it was necessary to develop a medical safety plan with emergency procedures. All medical and nonmedical test and operations personnel, except those specifically exempted, were required to meet the medical standards and proficiency levels as established. Implemented programs included health care of the test crew and their families, occupational medical services for chamber operating personnel, clinical laboratory support and hypobaric and other emergency support.

Advanced Stirling Convertor Dual Convertor Controller Testing at NASA Glenn Research Center in the Radioisotope Power Systems System Integration Laboratory

NASA Technical Reports Server (NTRS)

Dugala, Gina M.; Taylor, Linda M.; Bell, Mark E.; Dolce, James L.; Fraeman, Martin; Frankford, David P.

2015-01-01

NASA Glenn Research Center (GRC) developed a non-nuclear representation of a Radioisotope Power System (RPS) consisting of a pair of Advanced Stirling Convertors (ASC), a Dual Convertor Controller (DCC) EM (engineering model) 2 & 3, and associated support equipment, which were tested in the Radioisotope Power Systems System Integration Laboratory (RSIL). The DCC was designed by the Johns Hopkins University/Applied Physics Laboratory (JHU/APL) to actively control a pair of Advanced Stirling Convertors (ASC). The first phase of testing included a Dual Advanced Stirling Convertor Simulator (DASCS) which was developed by JHU/APL and simulates the operation and electrical behavior of a pair of ASC's in real time via a combination of hardware and software. RSIL provides insight into the electrical interactions between a representative radioisotope power generator, its associated control schemes, and realistic electric system loads. The first phase of integration testing included the following spacecraft bus configurations: capacitive, battery, and supercapacitor. A load profile, created based on data from several missions, tested the RPS and RSIL ability to maintain operation during load demands above and below the power provided by the RPS. The integration testing also confirmed the DCC's ability to disconnect from the spacecraft when the bus voltage dipped below 22 V or exceeded 36 V. Once operation was verified with the DASCS, the tests were repeated with actual operating ASC's. The goal of this integration testing was to verify operation of the DCC when connected to a spacecraft and to verify the functionality of the newly designed RSIL. The results of these tests are presented in this paper.

Site Environmental Report for Calendar Year 2011. DOE Operations at The Boeing Company Santa Susana Field Laboratory, Area IV

DOE Office of Scientific and Technical Information (OSTI.GOV)

Liu, Ning; Rutherford, Phil; Dassler, David

2012-09-01

This Annual Site Environmental Report (ASER) for 2011 describes the environmental conditions related to work performed for the Department of Energy (DOE) at Area IV of Boeing’s Santa Susana Field Laboratory (SSFL). The Energy Technology Engineering Center (ETEC), a government-owned, company-operated test facility, was located in Area IV. The operations in Area IV included development, fabrication, operation and disassembly of nuclear reactors, reactor fuel, and other radioactive materials. Other activities in the area involved the operation of large-scale liquid metal facilities that were used for testing non-nuclear liquid metal fast breeder reactor components. All nuclear work was terminated in 1988,more » and all subsequent radiological work has been directed toward environmental restoration and decontamination and decommissioning (D&D) of the former nuclear facilities and their associated sites. Liquid metal research and development ended in 2002. Since May 2007, the D&D operations in Area IV have been suspended by the DOE, but the environmental monitoring and characterization programs have continued. Results of the radiological monitoring program for the calendar year 2011 continue to indicate that there are no significant releases of radioactive material from Area IV of SSFL. All potential exposure pathways are sampled and/or monitored, including air, soil, surface water, groundwater, direct radiation, transfer of property (land, structures, waste), and recycling.« less

Site Environmental Report For Calendar Year 2012. DOE Operations at The Boeing Company Santa Susana Field Laboratory, Area IV

DOE Office of Scientific and Technical Information (OSTI.GOV)

Liu, Ning; Rutherford, Phil; Dassler, David

2013-09-01

This Annual Site Environmental Report (ASER) for 2012 describes the environmental conditions related to work performed for the Department of Energy (DOE) at Area IV of Boeing’s Santa Susana Field Laboratory (SSFL). The Energy Technology Engineering Center (ETEC), a government-owned, company-operated test facility, was located in Area IV. The operations in Area IV included development, fabrication, operation and disassembly of nuclear reactors, reactor fuel, and other radioactive materials. Other activities in the area involved the operation of large-scale liquid metal facilities that were used for testing non-nuclear liquid metal fast breeder reactor components. All nuclear work was terminated in 1988,more » and all subsequent radiological work has been directed toward environmental restoration and decontamination and decommissioning (D&D) of the former nuclear facilities and their associated sites. Liquid metal research and development ended in 2002. Since May 2007, the D&D operations in Area IV have been suspended by the DOE, but the environmental monitoring and characterization programs have continued. Results of the radiological monitoring program for the calendar year 2012 continue to indicate that there are no significant releases of radioactive material from Area IV of SSFL. All potential exposure pathways are sampled and/or monitored, including air, soil, surface water, groundwater, direct radiation, transfer of property (land, structures, waste), and recycling.« less

Biases encountered in long-term monitoring studies of invertebrates and microflora: Australian examples of protocols, personnel, tools and site location.

PubMed

Greenslade, Penelope; Florentine, Singarayer K; Hansen, Brigita D; Gell, Peter A

2016-08-01

Monitoring forms the basis for understanding ecological change. It relies on repeatability of methods to ensure detected changes accurately reflect the effect of environmental drivers. However, operator bias can influence the repeatability of field and laboratory work. We tested this for invertebrates and diatoms in three trials: (1) two operators swept invertebrates from heath vegetation, (2) four operators picked invertebrates from pyrethrum knockdown samples from tree trunk and (3) diatom identifications by eight operators in three laboratories. In each trial, operators were working simultaneously and their training in the field and laboratory was identical. No variation in catch efficiency was found between the two operators of differing experience using a random number of net sweeps to catch invertebrates when sequence, location and size of sweeps were random. Number of individuals and higher taxa collected by four operators from tree trunks varied significantly between operators and with their 'experience ranking'. Diatom identifications made by eight operators were clustered together according to which of three laboratories they belonged. These three tests demonstrated significant potential bias of operators in both field and laboratory. This is the first documented case demonstrating the significant influence of observer bias on results from invertebrate field-based studies. Examples of two long-term trials are also given that illustrate further operator bias. Our results suggest that long-term ecological studies using invertebrates need to be rigorously audited to ensure that operator bias is accounted for during analysis and interpretation. Further, taxonomic harmonisation remains an important step in merging field and laboratory data collected by different operators.

Virtual and remote robotic laboratory using EJS, MATLAB and LabVIEW.

PubMed

Chaos, Dictino; Chacón, Jesús; Lopez-Orozco, Jose Antonio; Dormido, Sebastián

2013-02-21

This paper describes the design and implementation of a virtual and remote laboratory based on Easy Java Simulations (EJS) and LabVIEW. The main application of this laboratory is to improve the study of sensors in Mobile Robotics, dealing with the problems that arise on the real world experiments. This laboratory allows the user to work from their homes, tele-operating a real robot that takes measurements from its sensors in order to obtain a map of its environment. In addition, the application allows interacting with a robot simulation (virtual laboratory) or with a real robot (remote laboratory), with the same simple and intuitive graphical user interface in EJS. Thus, students can develop signal processing and control algorithms for the robot in simulation and then deploy them on the real robot for testing purposes. Practical examples of application of the laboratory on the inter-University Master of Systems Engineering and Automatic Control are presented.

Virtual and Remote Robotic Laboratory Using EJS, MATLAB and Lab VIEW

PubMed Central

Chaos, Dictino; Chacón, Jesús; Lopez-Orozco, Jose Antonio; Dormido, Sebastián

2013-01-01

This paper describes the design and implementation of a virtual and remote laboratory based on Easy Java Simulations (EJS) and LabVIEW. The main application of this laboratory is to improve the study of sensors in Mobile Robotics, dealing with the problems that arise on the real world experiments. This laboratory allows the user to work from their homes, tele-operating a real robot that takes measurements from its sensors in order to obtain a map of its environment. In addition, the application allows interacting with a robot simulation (virtual laboratory) or with a real robot (remote laboratory), with the same simple and intuitive graphical user interface in EJS. Thus, students can develop signal processing and control algorithms for the robot in simulation and then deploy them on the real robot for testing purposes. Practical examples of application of the laboratory on the inter-University Master of Systems Engineering and Automatic Control are presented. PMID:23429578

[Software for illustrating a cost-quality balance carried out by clinical laboratory practice].

PubMed

Nishibori, Masahiro; Asayama, Hitoshi; Kimura, Satoshi; Takagi, Yasushi; Hagihara, Michio; Fujiwara, Mutsunori; Yoneyama, Akiko; Watanabe, Takashi

2010-09-01

We have no proper reference indicating the quality of clinical laboratory practice, which should clearly illustrates that better medical tests require more expenses. Japanese Society of Laboratory Medicine was concerned about recent difficult medical economy and issued a committee report proposing a guideline to evaluate the good laboratory practice. According to the guideline, we developed software that illustrate a cost-quality balance carried out by clinical laboratory practice. We encountered a number of controversial problems, for example, how to measure and weight each quality-related factor, how to calculate costs of a laboratory test and how to consider characteristics of a clinical laboratory. Consequently we finished only prototype software within the given period and the budget. In this paper, software implementation of the guideline and the above-mentioned problems are summarized. Aiming to stimulate these discussions, the operative software will be put on the Society's homepage for trial

Advances in Discrete-Event Simulation for MSL Command Validation

NASA Technical Reports Server (NTRS)

Patrikalakis, Alexander; O'Reilly, Taifun

2013-01-01

In the last five years, the discrete event simulator, SEQuence GENerator (SEQGEN), developed at the Jet Propulsion Laboratory to plan deep-space missions, has greatly increased uplink operations capacity to deal with increasingly complicated missions. In this paper, we describe how the Mars Science Laboratory (MSL) project makes full use of an interpreted environment to simulate change in more than fifty thousand flight software parameters and conditional command sequences to predict the result of executing a conditional branch in a command sequence, and enable the ability to warn users whenever one or more simulated spacecraft states change in an unexpected manner. Using these new SEQGEN features, operators plan more activities in one sol than ever before.

Burner Rig in the Material and Stresses Building

NASA Image and Video Library

1969-11-21

A burner rig heats up a material sample in the Materials and Stresses Building at the National Aeronautics and Space Administration (NASA) Lewis Research Center. Materials technology is an important element in the successful development of advanced airbreathing and rocket propulsion systems. Different types of engines operate in different environments so an array of dependable materials is needed. NASA Lewis began investigating the characteristics of different materials shortly after World War II. In 1949 the materials group was expanded into its own division. The Lewis researchers sought to study and test materials in environments that simulate the environment in which they would operate. The Materials and Stresses Building, built in 1949, contained a number of laboratories to analyze the materials. They are subjected to high temperatures, high stresses, corrosion, irradiation, and hot gasses. The Physics of Solids Laboratory included a cyclotron, cloud chamber, helium cryostat, and metallurgy cave. The Metallographic Laboratory possessed six x-ray diffraction machines, two metalloscopes, and other equipment. The Furnace Room had two large induction machines, a 4500⁰ F graphite furnace, and heat treating equipment. The Powder Laboratory included 60-ton and 3000-ton presses. The Stresses Laboratory included stress rupture machines, fatigue machines, and tensile strength machines.

Online Analysis of Wind and Solar Part I: Ramping Tool

DOE Office of Scientific and Technical Information (OSTI.GOV)

Etingov, Pavel V.; Ma, Jian; Makarov, Yuri V.

2012-01-31

To facilitate wider penetration of renewable resources without compromising system reliability concerns arising from the lack of predictability of intermittent renewable resources, a tool for use by California Independent System Operator (CAISO) power grid operators was developed by Pacific Northwest National Laboratory (PNNL) in conjunction with CAISO with funding from California Energy Commission. This tool predicts and displays additional capacity and ramping requirements caused by uncertainties in forecasts of loads and renewable generation. The tool is currently operational in the CAISO operations center. This is one of two final reports on the project.

Clinical laboratory as an economic model for business performance analysis

PubMed Central

Buljanović, Vikica; Patajac, Hrvoje; Petrovečki, Mladen

2011-01-01

Aim To perform SWOT (strengths, weaknesses, opportunities, and threats) analysis of a clinical laboratory as an economic model that may be used to improve business performance of laboratories by removing weaknesses, minimizing threats, and using external opportunities and internal strengths. Methods Impact of possible threats to and weaknesses of the Clinical Laboratory at Našice General County Hospital business performance and use of strengths and opportunities to improve operating profit were simulated using models created on the basis of SWOT analysis results. The operating profit as a measure of profitability of the clinical laboratory was defined as total revenue minus total expenses and presented using a profit and loss account. Changes in the input parameters in the profit and loss account for 2008 were determined using opportunities and potential threats, and economic sensitivity analysis was made by using changes in the key parameters. The profit and loss account and economic sensitivity analysis were tools for quantifying the impact of changes in the revenues and expenses on the business operations of clinical laboratory. Results Results of simulation models showed that operational profit of €470 723 in 2008 could be reduced to only €21 542 if all possible threats became a reality and current weaknesses remained the same. Also, operational gain could be increased to €535 804 if laboratory strengths and opportunities were utilized. If both the opportunities and threats became a reality, the operational profit would decrease by €384 465. Conclusion The operational profit of the clinical laboratory could be significantly reduced if all threats became a reality and the current weaknesses remained the same. The operational profit could be increased by utilizing strengths and opportunities as much as possible. This type of modeling may be used to monitor business operations of any clinical laboratory and improve its financial situation by implementing changes in the next fiscal period. PMID:21853546

Clinical laboratory as an economic model for business performance analysis.

PubMed

Buljanović, Vikica; Patajac, Hrvoje; Petrovecki, Mladen

2011-08-15

To perform SWOT (strengths, weaknesses, opportunities, and threats) analysis of a clinical laboratory as an economic model that may be used to improve business performance of laboratories by removing weaknesses, minimizing threats, and using external opportunities and internal strengths. Impact of possible threats to and weaknesses of the Clinical Laboratory at Našice General County Hospital business performance and use of strengths and opportunities to improve operating profit were simulated using models created on the basis of SWOT analysis results. The operating profit as a measure of profitability of the clinical laboratory was defined as total revenue minus total expenses and presented using a profit and loss account. Changes in the input parameters in the profit and loss account for 2008 were determined using opportunities and potential threats, and economic sensitivity analysis was made by using changes in the key parameters. The profit and loss account and economic sensitivity analysis were tools for quantifying the impact of changes in the revenues and expenses on the business operations of clinical laboratory. Results of simulation models showed that operational profit of €470 723 in 2008 could be reduced to only €21 542 if all possible threats became a reality and current weaknesses remained the same. Also, operational gain could be increased to €535 804 if laboratory strengths and opportunities were utilized. If both the opportunities and threats became a reality, the operational profit would decrease by €384 465. The operational profit of the clinical laboratory could be significantly reduced if all threats became a reality and the current weaknesses remained the same. The operational profit could be increased by utilizing strengths and opportunities as much as possible. This type of modeling may be used to monitor business operations of any clinical laboratory and improve its financial situation by implementing changes in the next fiscal period.

Highly Integrated Quality Assurance – An Empirical Case

DOE Office of Scientific and Technical Information (OSTI.GOV)

Drake Kirkham; Amy Powell; Lucas Rich

2011-02-01

Highly Integrated Quality Assurance – An Empirical Case Drake Kirkham1, Amy Powell2, Lucas Rich3 1Quality Manager, Radioisotope Power Systems (RPS) Program, Idaho National Laboratory, P.O. Box 1625 M/S 6122, Idaho Falls, ID 83415-6122 2Quality Engineer, RPS Program, Idaho National Laboratory 3Quality Engineer, RPS Program, Idaho National Laboratory Contact: Voice: (208) 533-7550 Email: Drake.Kirkham@inl.gov Abstract. The Radioisotope Power Systems Program of the Idaho National Laboratory makes an empirical case for a highly integrated Quality Assurance function pertaining to the preparation, assembly, testing, storage and transportation of 238Pu fueled radioisotope thermoelectric generators. Case data represents multiple campaigns including the Pluto/New Horizons mission,more » the Mars Science Laboratory mission in progress, and other related projects. Traditional Quality Assurance models would attempt to reduce cost by minimizing the role of dedicated Quality Assurance personnel in favor of either functional tasking or peer-based implementations. Highly integrated Quality Assurance adds value by placing trained quality inspectors on the production floor side-by-side with nuclear facility operators to enhance team dynamics, reduce inspection wait time, and provide for immediate, independent feedback. Value is also added by maintaining dedicated Quality Engineers to provide for rapid identification and resolution of corrective action, enhanced and expedited supply chain interfaces, improved bonded storage capabilities, and technical resources for requirements management including data package development and Certificates of Inspection. A broad examination of cost-benefit indicates highly integrated Quality Assurance can reduce cost through the mitigation of risk and reducing administrative burden thereby allowing engineers to be engineers, nuclear operators to be nuclear operators, and the cross-functional team to operate more efficiently. Applicability of this case extends to any high-value, long-term project where traceability and accountability are determining factors.« less

Liquid-Phase Adsorption Fundamentals.

ERIC Educational Resources Information Center

Cooney, David O.

1987-01-01

Describes an experiment developed and used in the unit operations laboratory course at the University of Wyoming. Involves the liquid-phase adsorption of an organic compound from aqueous solution on activated carbon, and is relevant to adsorption processes in general. (TW)

Laboratory evaluation of alcohol safety interlock systems. Volume 1 : summary report

DOT National Transportation Integrated Search

1974-01-01

The report contains the results of an experimental and analytical evaluation of instruments and techniques designed to prevent an intoxicated driver from operating his automobile. The prototype 'Alcohol Safety Interlock Systems' tested were developed...

III-V infrared research at the Jet Propulsion Laboratory

NASA Astrophysics Data System (ADS)

Gunapala, S. D.; Ting, D. Z.; Hill, C. J.; Soibel, A.; Liu, John; Liu, J. K.; Mumolo, J. M.; Keo, S. A.; Nguyen, J.; Bandara, S. V.; Tidrow, M. Z.

2009-08-01

Jet Propulsion Laboratory is actively developing the III-V based infrared detector and focal plane arrays (FPAs) for NASA, DoD, and commercial applications. Currently, we are working on multi-band Quantum Well Infrared Photodetectors (QWIPs), Superlattice detectors, and Quantum Dot Infrared Photodetector (QDIPs) technologies suitable for high pixel-pixel uniformity and high pixel operability large area imaging arrays. In this paper we report the first demonstration of the megapixel-simultaneously-readable and pixel-co-registered dual-band QWIP focal plane array (FPA). In addition, we will present the latest advances in QDIPs and Superlattice infrared detectors at the Jet Propulsion Laboratory.

The Pathology Laboratory Act 2007 explained.

PubMed

Looi, Lai-Meng

2008-06-01

The past century has seen tremendous changes in the scope and practice of pathology laboratories in tandem with the development of the medical services in Malaysia. Major progress was made in the areas of training and specialization of pathologists and laboratory technical staff. Today the pathology laboratory services have entered the International arena, and are propelled along the wave of globalization. Many new challenges have emerged as have new players in the field. Landmark developments over the past decade include the establishment of national quality assurance programmes, the mushrooming of private pathology laboratories, the establishment of a National Accreditation Standard for medical testing laboratories based on ISO 15189, and the passing of the Pathology Laboratory Act in Parliament in mid-2007. The Pathology Laboratory Act 2007 seeks to ensure that the pathology laboratory is accountable to the public, meets required standards of practice, participates in Quality Assurance programmes, is run by qualified staff, complies with safety requirements and is subject to continuous audit. The Act is applicable to all private laboratories (stand alone or hospital) and laboratories in statutory bodies (Universities, foundations). It is not applicable to public laboratories (established and operated by the government) and side-room laboratories established in clinics of registered medical or dental practitioners for their own patients (tests as in the First and Second Schedules respectively). Tests of the Third Schedule (home test blood glucose, urine glucose, urine pregnancy test) are also exempted. The Act has 13 Parts and provides for control of the pathology laboratory through approval (to establish and maintain) and licensing (to operate or provide). The approval or license may only be issued to a sole proprietor, partnership or body corporate, and then only if the entity includes a registered medical practitioner. Details of personnel qualifications and laboratory practices are left to be specified by the Director-General of Health, providing for a formal recognition process and room for revision as pathology practices evolve. Encompassed in the responsibilities of the licensee is the requirement that samples are received and results issued through, and management vested in, a registered medical or dental practitioner. This effectively prohibits "walk-ins" to the laboratory and indiscriminate public screening. The requirement for a person-in-charge in accordance with class and speciality of laboratory ensures that the laboratory is under the charge of the pathology profession. Examined carefully, the requirements of the Act are similar to laboratory accreditation, but are backed by legislation. Many of these details will be spelt out in the Regulations, and these in turn are likely to fall back on National professional guidelines, as accreditation does. Although not at first obvious, enforcement of the Act is based on self-regulation by pathology laboratory professionals. Sincere professional input is thus required to embrace its philosophy, ensure rational and transparent enforcement of legislation, and develop National guidelines for good pathology practices upon which enforcement may be based.

[The development and implementation of polymerase chain reaction to detect in real-time operation mode yersinia pestis in field material].

PubMed

Afanas'ev, M V; Chipanin, E V; Shestakov, V E; Denisov, A V; Fomina, L A; Ostiak, A S; Balakhonov, S V

2013-03-01

The article presents the results of development and practical implementation of system of polymerase chain reaction testing in real-time operation mode to detect agent of plague infield material. In laboratory conditions the system demonstrated good results and hence it was applied in conditions of field laboratory of epidemiologic team during planned epizootologic examination of Gorno-Altaisk hot spot of plague. The sampling consisted of more than 1400 objects. It was demonstrated that high sensitivity and specificity is immanent to proposed system. The adaptation of the system to the real time amplifier "Smart Cycler" (Cephid, USA) having some specific technical characteristics makes it possible to consider the proposed test-system as an effective sensitive and precise instrument for screening studies in the process of regular epizootologic examinations of hot spots of plague.

A Multi-mission Event-Driven Component-Based System for Support of Flight Software Development, ATLO, and Operations first used by the Mars Science Laboratory (MSL) Project

NASA Technical Reports Server (NTRS)

Dehghani, Navid; Tankenson, Michael

2006-01-01

This paper details an architectural description of the Mission Data Processing and Control System (MPCS), an event-driven, multi-mission ground data processing components providing uplink, downlink, and data management capabilities which will support the Mars Science Laboratory (MSL) project as its first target mission. MPCS is developed based on a set of small reusable components, implemented in Java, each designed with a specific function and well-defined interfaces. An industry standard messaging bus is used to transfer information among system components. Components generate standard messages which are used to capture system information, as well as triggers to support the event-driven architecture of the system. Event-driven systems are highly desirable for processing high-rate telemetry (science and engineering) data, and for supporting automation for many mission operations processes.

ORNL Sustainable Campus Initiative

DOE Office of Scientific and Technical Information (OSTI.GOV)

Halford, Christopher K

2012-01-01

The research conducted at Oak Ridge National Laboratory (ORNL) spans many disciplines and has the potential for far-reaching impact in many areas of everyday life. ORNL researchers and operations staff work on projects in areas as diverse as nuclear power generation, transportation, materials science, computing, and building technologies. As the U.S. Department of Energy s (DOE) largest science and energy research facility, ORNL seeks to establish partnerships with industry in the development of innovative new technologies. The primary focus of this current research deals with developing technologies which improve or maintain the quality of life for humans while reducing themore » overall impact on the environment. In its interactions with industry, ORNL serves as both a facility for sustainable research, as well as a representative of DOE to the private sector. For these reasons it is important that the everyday operations of the Laboratory reflect a dedication to the concepts of stewardship and sustainability.« less

Technical developments at the NASA Space Radiation Laboratory.

PubMed

Lowenstein, D I; Rusek, A

2007-06-01

The NASA Space Radiation Laboratory (NSRL) located at Brookhaven National Laboratory (BNL) is a center for space radiation research in both the life and physical sciences. BNL is a multidisciplinary research facility operated for the Office of Science of the US Department of Energy (DOE). The BNL scientific research portfolio supports a large and diverse science and technology program including research in nuclear and high-energy physics, material science, chemistry, biology, medial science, and nuclear safeguards and security. NSRL, in operation since July 2003, is an accelerator-based facility which provides particle beams for radiobiology and physics studies (Lowenstein in Phys Med 17(supplement 1):26-29 2001). The program focus is to measure the risks and to ameliorate the effects of radiation encountered in space, both in low earth orbit and extended missions beyond the earth. The particle beams are produced by the Booster synchrotron, an accelerator that makes up part of the injector sequence of the DOE nuclear physics program's Relativistic Heavy Ion Collider. Ion species from protons to gold are presently available, at energies ranging from <100 to >1,000 MeV/n. The NSRL facility has recently brought into operation the ability to rapidly switch species and beam energy to supply a varied spectrum onto a given specimen. A summary of past operation performance, plans for future operations and recent and planned hardware upgrades will be described.

21 CFR 58.81 - Standard operating procedures.

Code of Federal Regulations, 2010 CFR

2010-04-01

... LABORATORY PRACTICE FOR NONCLINICAL LABORATORY STUDIES Testing Facilities Operation § 58.81 Standard operating procedures. (a) A testing facility shall have standard operating procedures in writing setting... following: (1) Animal room preparation. (2) Animal care. (3) Receipt, identification, storage, handling...

21 CFR 58.81 - Standard operating procedures.

Code of Federal Regulations, 2013 CFR

2013-04-01

... LABORATORY PRACTICE FOR NONCLINICAL LABORATORY STUDIES Testing Facilities Operation § 58.81 Standard operating procedures. (a) A testing facility shall have standard operating procedures in writing setting... following: (1) Animal room preparation. (2) Animal care. (3) Receipt, identification, storage, handling...

21 CFR 58.81 - Standard operating procedures.

Code of Federal Regulations, 2012 CFR

2012-04-01

... LABORATORY PRACTICE FOR NONCLINICAL LABORATORY STUDIES Testing Facilities Operation § 58.81 Standard operating procedures. (a) A testing facility shall have standard operating procedures in writing setting... following: (1) Animal room preparation. (2) Animal care. (3) Receipt, identification, storage, handling...

21 CFR 58.81 - Standard operating procedures.

Code of Federal Regulations, 2014 CFR

2014-04-01

... LABORATORY PRACTICE FOR NONCLINICAL LABORATORY STUDIES Testing Facilities Operation § 58.81 Standard operating procedures. (a) A testing facility shall have standard operating procedures in writing setting... following: (1) Animal room preparation. (2) Animal care. (3) Receipt, identification, storage, handling...

Establishment of Next-Generation Neurosurgery Research and Training Laboratory with Integrated Human Performance Monitoring.

PubMed

Bernardo, Antonio

2017-10-01

Quality of neurosurgical care and patient outcomes are inextricably linked to surgical and technical proficiency and a thorough working knowledge of microsurgical anatomy. Neurosurgical laboratory-based cadaveric training is essential for the development and refinement of technical skills before their use on a living patient. Recent biotechnological advances including 3-dimensional (3D) microscopy and endoscopy, 3D printing, virtual reality, surgical simulation, surgical robotics, and advanced neuroimaging have proved to reduce the learning curve, improve conceptual understanding of complex anatomy, and enhance visuospatial skills in neurosurgical training. Until recently, few means have allowed surgeons to obtain integrated surgical and technological training in an operating room setting. We report on a new model, currently in use at our institution, for technologically integrated surgical training and innovation using a next-generation microneurosurgery skull base laboratory designed to recreate the setting of a working operating room. Each workstation is equipped with a 3D surgical microscope, 3D endoscope, surgical drills, operating table with a Mayfield head holder, and a complete set of microsurgical tools. The laboratory also houses a neuronavigation system, a surgical robotic, a surgical planning system, 3D visualization, virtual reality, and computerized simulation for training of surgical procedures and visuospatial skills. In addition, the laboratory is equipped with neurophysiological monitoring equipment in order to conduct research into human factors in surgery and the respective roles of workload and fatigue on surgeons' performance. Copyright © 2017 Elsevier Inc. All rights reserved.

Mechanisms and kinetics of cellulose fermentation for protein production

NASA Technical Reports Server (NTRS)

Dunlap, C. A.

1971-01-01

The development of a process (and ancillary processing and analytical techniques) to produce bacterial single-cell protein of good nutritional quality from waste cellulose is discussed. A fermentation pilot plant and laboratory were developed and have been in operation for about two years. Single-cell protein (SCP) can be produced from sugarcane bagasse--a typical agricultural cellulosic waste. The optimization and understanding of this process and its controlling variables are examined. Both batch and continuous fermentation runs have been made under controlled conditions in the 535 liter pilot plant vessel and in the laboratory 14-liter fermenters.

Surgical simulation in orthopaedic skills training.

PubMed

Atesok, Kivanc; Mabrey, Jay D; Jazrawi, Laith M; Egol, Kenneth A

2012-07-01

Mastering rapidly evolving orthopaedic surgical techniques requires a lengthy period of training. Current work-hour restrictions and cost pressures force trainees to face the challenge of acquiring more complex surgical skills in a shorter amount of time. As a result, alternative methods to improve the surgical skills of orthopaedic trainees outside the operating room have been developed. These methods include hands-on training in a laboratory setting using synthetic bones or cadaver models as well as software tools and computerized simulators that enable trainees to plan and simulate orthopaedic operations in a three-dimensional virtual environment. Laboratory-based training offers potential benefits in the development of basic surgical skills, such as using surgical tools and implants appropriately, achieving competency in procedures that have a steep learning curve, and assessing already acquired skills while minimizing concerns for patient safety, operating room time, and financial constraints. Current evidence supporting the educational advantages of surgical simulation in orthopaedic skills training is limited. Despite this, positive effects on the overall education of orthopaedic residents, and on maintaining the proficiency of practicing orthopaedic surgeons, are anticipated.

Artificial intelligence in a mission operations and satellite test environment

NASA Technical Reports Server (NTRS)

Busse, Carl

1988-01-01

A Generic Mission Operations System using Expert System technology to demonstrate the potential of Artificial Intelligence (AI) automated monitor and control functions in a Mission Operations and Satellite Test environment will be developed at the National Aeronautics and Space Administration (NASA) Jet Propulsion Laboratory (JPL). Expert system techniques in a real time operation environment are being studied and applied to science and engineering data processing. Advanced decommutation schemes and intelligent display technology will be examined to develop imaginative improvements in rapid interpretation and distribution of information. The Generic Payload Operations Control Center (GPOCC) will demonstrate improved data handling accuracy, flexibility, and responsiveness in a complex mission environment. The ultimate goal is to automate repetitious mission operations, instrument, and satellite test functions by the applications of expert system technology and artificial intelligence resources and to enhance the level of man-machine sophistication.

Successful development of first-generation laser device; marking China's optoelectronic technology at world class level

NASA Astrophysics Data System (ADS)

1995-04-01

Bell Laboratories has developed the world's first optical information processor. Its core device is a self-excited electrooptical effect apparatus array of symmetric operation. After being developed in the United States, this high-technology device was successfully developed by China's scientists,thus making the fact that China's optoelectronic technology is among the most advanced in the world.

Intermediate quality control tests in the development of a superconducting RF cryomodule for CW operation

NASA Astrophysics Data System (ADS)

Pattalwar, Shrikant; Jones, Thomas; Strachan, John; Bate, Robert; Davies, Phil; McIntosh, Peter

2012-06-01

Through an international cryomodule collaboration, ASTeC at Daresbury Laboratory has taken the primary responsibility in leading the development of an optimised Superconducting RF (SRF) cryomodule, operating in CW mode for energy recovery facilities and other high duty cycle accelerators. For high beam current operation, Higher Order Mode (HOM) absorbers are critical components of the SRF Cryomodule, ensuring excessive heating of the accelerating structures and beam instabilities are effectively managed. This paper describes some of the cold tests conducted on the HOM absorbers and other critical components during the construction phase, to ensure that the quality and reliable cryomodule performance is maintained.

Development and operating experience of a short-period superconducting undulator at the Advanced Photon Source

DOE PAGES

Ivanyushenkov, Y.; Harkay, K.; Abliz, M.; ...

2015-04-01

In this study, a decade-long effort at the Advanced Photon Source (APS) of Argonne National Laboratory (ANL) on development of superconducting undulators culminated in December 2012 with the installation of the first superconducting undulator “SCU0” into Sector 6 of the APS storage ring. The device was commissioned in January 2013 and has been in user operation since. This paper presents the magnetic and cryogenic design of the SCU0 together with the results of stand-alone cold tests. The initial commissioning and characterization of SCU0 as well as its operating experience in the APS storage ring are described.

Autonomous Dome for a Robotic Telescope

NASA Astrophysics Data System (ADS)

Kumar, A.; Sengupta, A.; Ganesh, S.

2016-12-01

The Physical Research Laboratory operates a 50 cm robotic observatory at Mount Abu (Rajsthan, India). This Automated Telescope for Variability Studies (ATVS) makes use of the Remote Telescope System 2 (RTS2) for autonomous operations. The observatory uses a 3.5 m dome from Sirius Observatories. We have developed electronics using Arduino electronic circuit boards with home grown logic and software to control the dome operations. We are in the process of completing the drivers to link our Arduino based dome controller with RTS2. This document is a short description of the various phases of the development and their integration to achieve the required objective.

The impact of SLMTA in improving laboratory quality systems in the Caribbean Region

PubMed Central

Gordon, Floris; Irving, Yvette; Whyms, Ismae; Parris, Keith; Beckles, Songee; Maruta, Talkmore; Ndlovu, Nqobile; Albalak, Rachel; Alemnji, George

2014-01-01

Background Past efforts to improve laboratory quality systems and to achieve accreditation for better patient care in the Caribbean Region have been slow. Objective To describe the impact of the Strengthening of Laboratory Management Toward Accreditation (SLMTA) training programme and mentorship amongst five clinical laboratories in the Caribbean after 18 months. Method Five national reference laboratories from four countries participated in the SLMTA programme that incorporated classroom teaching and implementation of improvement projects. Mentors were assigned to the laboratories to guide trainees on their improvement projects and to assist in the development of Quality Management Systems (QMS). Audits were conducted at baseline, six months, exit (at 12 months) and post-SLMTA (at 18 months) using the Stepwise Laboratory Quality Improvement Process Towards Accreditation (SLIPTA) checklist to measure changes in implementation of the QMS during the period. At the end of each audit, a comprehensive implementation plan was developed in order to address gaps. Results Baseline audit scores ranged from 19% to 52%, corresponding to 0 stars on the SLIPTA five-star scale. After 18 months, one laboratory reached four stars, two reached three stars and two reached two stars. There was a corresponding decrease in nonconformities and development of over 100 management and technical standard operating procedures in each of the five laboratories. Conclusion The tremendous improvement in these five Caribbean laboratories shows that SLMTA coupled with mentorship is an effective, user-friendly, flexible and customisable approach to the implementation of laboratory QMS. It is recommended that other laboratories in the region consider using the SLMTA training programme as they engage in quality systems improvement and preparation for accreditation. PMID:27066396

DEVELOPMENT AND EVALUATION OF A CONTINUOUS COARSE (PM10-PM2.5) PARTICLE MONITOR

EPA Science Inventory

In this paper, we describe the development and laboratory and field evaluation of a continuous coarse (2.5-10 um) particle mass (PM) monitor that can provide reliable measurements of the coarse mass (CM) concentrations in time intervals as short as 5-10 min. The operating princ...

Establishing the Information System: An Operational Handbook. MOREL Regional Information System for Educators.

ERIC Educational Resources Information Center

Kromer, Charles; Doyle, James

This document is one of a series describing the background, functions, and utilization of the Regional Information System (RIS), developed by the Michigan-Ohio Regional Educational Laboratory (MOREL). RIS, which was developed to improve the accessibility of information for the educational practitioner, is described in this handbook. The handbook…

Integrating Standard Operating Procedures and Industry Notebook Standards to Evaluate Students in Laboratory Courses

ERIC Educational Resources Information Center

Wallert, Mark A.; Provost, Joseph J.

2014-01-01

To enhance the preparedness of graduates from the Biochemistry and Biotechnology (BCBT) Major at Minnesota State University Moorhead for employment in the bioscience industry we have developed a new Industry certificate program. The BCBT Industry Certificate was developed to address specific skill sets that local, regional, and national industry…

Expert Systems on Multiprocessor Architectures. Phase 1

DTIC Science & Technology

1988-08-01

great rate) as early experience indicates what alternative aspect of system operation should have been monitored in any given completed run. The... system operation should have been monitored in any given completed run. The design goals that emerged then were (1) that the simulation system should...ORGANIZATION 6b OFFICE SYMBOL 7a. NAME OF MONITORING ORGANIZATION Stanford University (If applicable) Knowledge Systems Laboratory Rome Air Development

Navy Manpower Planning and Programming: Basis for Systems Examination

DTIC Science & Technology

1974-10-01

IRE5EARCH AND DEVEl. INAVAL RESEARCH] CHIEF OF NAVAL OPERATIONS OFFICE CHIIf OF NAVAL OPERATIONS NAVAL MATERIAL COMMAND •LitMARTERS NAVAL MATERIAL...DIVISION COMPENSATION BRANCH MANPOWER PROGRAMMING ■RANCH JOURNAL/TRADE TALK BRANCH 06A ASSISTANT FOR COMPUTER SCIENCES SYSTEMS DEVELOPMENT BRANCH...Assistant Director, Life Sciences , Air Force Office of Scientific Research Technical Library, Air Force Human Resources Laboratory, Lackland Air Force Base

Production and aerial application of wood shreds as a post-fire hillslope erosion mitigation treatment

Treesearch

Peter R. Robichaud; Louise E. Ashmun; Randy B. Foltz; Charles G. Showers; J. Scott Groenier; Jennifer Kesler; Claire DeLeo; Mary Moore

2013-01-01

Guidelines for the production and aerial application of wood shred mulch as a post-fire hillslope treatment were developed from laboratory and field studies, several field operations, and the evaluations of professionals involved in those operations. At two early trial sites, the wood shred mulch was produced off-site and transported to the area of use. At the 2010...

Testing Report: Littleford-Day Dryer Operation: Dryer Operation Impacts of Proposed MIS Mitigation Changes

DOE Office of Scientific and Technical Information (OSTI.GOV)

Shimskey, Rick W.; Buchmiller, William C.; Elmore, Monte R.

2007-06-01

Pacific Northwest National Laboratory performed a series of tests using the Littleford Day 22-liter dryer during investigations that evaluated changes in the melter-feed composition for the Demonstration Bulk Vitrification System. During testing, a new melter-feed formulation was developed that improved dryer performance while improving the retention of waste salts in the melter feed during vitrification.

A validated methodology for determination of laboratory instrument computer interface efficacy

NASA Astrophysics Data System (ADS)

1984-12-01

This report is intended to provide a methodology for determining when, and for which instruments, direct interfacing of laboratory instrument and laboratory computers is beneficial. This methodology has been developed to assist the Tri-Service Medical Information Systems Program Office in making future decisions regarding laboratory instrument interfaces. We have calculated the time savings required to reach a break-even point for a range of instrument interface prices and corresponding average annual costs. The break-even analyses used empirical data to estimate the number of data points run per day that are required to meet the break-even point. The results indicate, for example, that at a purchase price of $3,000, an instrument interface will be cost-effective if the instrument is utilized for at least 154 data points per day if operated in the continuous mode, or 216 points per day if operated in the discrete mode. Although this model can help to ensure that instrument interfaces are cost effective, additional information should be considered in making the interface decisions. A reduction in results transcription errors may be a major benefit of instrument interfacing.

Nextgen Technologies for Mid-Term and Far-Term Air Traffic Control Operations

NASA Technical Reports Server (NTRS)

Prevot, Thomas

2009-01-01

This paper describes technologies for mid-term and far-term air traffic control operations in the Next Generation Air Transportation System (NextGen). The technologies were developed and evaluated with human-in-the-loop simulations in the Airspace Operations Laboratory (AOL) at the NASA Ames Research Center. The simulations were funded by several research focus areas within NASA's Airspace Systems program and some were co-funded by the FAA's Air Traffic Organization for Planning, Research and Technology.

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

Monsanto Research Corporation operates Mound Laboratory, a government-owned facility of the U.S. Energy Research and Development Administration, at Miamisburg, Ohio. Mound Laboratory is an integrated research, development, and production facility performing work in support of ERDA weapon and non-weapon programs with emphasis on explosive and nuclear technology. Mound Laboratory originated as a technical organization in 1943 when Monsanto Chemical Company was requested to accept responsibility for determining the chemical and metallurgical properties of polonium as a project of the Manhattan Engineering District. Work was carried on at Monsanto`s Central Research Department and several satellite units in the Dayton, Ohio area.more » Late in 1945, the Manhattan Engineering District determined that the research, development and production organization established by Monsanto at Dayton should become a permanent facility. A search for a suitable location in early 1946 led to the selection of a 180-acre tract adjacent to Miamisburg, about ten miles (16 km) south of Dayton.« less

Report for Task 8.4: Development of Control Room Layout Recommendations

DOE Office of Scientific and Technical Information (OSTI.GOV)

McDonald, Robert

Idaho National Laboratory (INL) has contracted Institutt for Energiteknikk (IFE) to support in the development of an end state vision for the US Nuclear industry and in particular for a utility that is currently moving forward with a control room modernization project. This support includes the development of an Overview display and technical support in conducting an operational study. Development of operational scenarios to be conducted using a full scope simulator at the INL HSSL. Additionally IFE will use the CREATE modelling tool to provide 3-D views of the potential and possible end state view after the completion of digitalmore » upgrade project.« less

The natural space environment: Effects on spacecraft

NASA Technical Reports Server (NTRS)

James, Bonnie F.; Norton, O. W. (Compiler); Alexander, Margaret B. (Editor)

1994-01-01

The effects of the natural space environments on spacecraft design, development, and operation are the topic of a series of NASA Reference Publications currently being developed by the Electromagnetics and Environments Branch, Systems Analysis and Integration Laboratory, Marshall Space Flight Center. This primer provides an overview of the natural space environments and their effect on spacecraft design, development, and operations, and also highlights some of the new developments in science and technology for each space environment. It is hoped that a better understanding of the space environment and its effect on spacecraft will enable program management to more effectively minimize program risks and costs, optimize design quality, and successfully achieve mission objectives.

Safety validation test equipment operation

NASA Astrophysics Data System (ADS)

Kurosaki, Tadaaki; Watanabe, Takashi

1992-08-01

An overview of the activities conducted on safety validation test equipment operation for materials used for NASA manned missions is presented. Safety validation tests, such as flammability, odor, offgassing, and so forth were conducted in accordance with NASA-NHB-8060.1C using test subjects common with those used by NASA, and the equipment used were qualified for their functions and performances in accordance with NASDA-CR-99124 'Safety Validation Test Qualification Procedures.' Test procedure systems were established by preparing 'Common Procedures for Safety Validation Test' as well as test procedures for flammability, offgassing, and odor tests. The test operation organization chaired by the General Manager of the Parts and Material Laboratory of NASDA (National Space Development Agency of Japan) was established, and the test leaders and operators in the organization were qualified in accordance with the specified procedures. One-hundred-one tests had been conducted so far by the Parts and Material Laboratory according to the request submitted by the manufacturers through the Space Station Group and the Safety and Product Assurance for Manned Systems Office.

Research on the Use of Robotics in Hazardous Environments at Sandia National Laboratories

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kwok, Kwan S.

Many hazardous material handling needs exist in remote unstructured environments. Currently these operations are accomplished using personnel in direct contact with the hazards. A safe and cost effective alternative to this approach is the use of intelligent robotic systems for safe handling, packaging, transport, and even excavation of hazardous materials. The Intelligent Systems and Robotics Center of Sandia National Laboratories has developed and deployed robotic technologies for use in hazardous environments, three of which have been deployed in DOE production facilities for handling of special nuclear materials. Other systems are currently under development for packaging special nuclear materials. This papermore » presents an overview of the research activities, including five delivered systems, at %ndia National Laboratories on the use of robotics in hazardous environments.« less

Importance of implementing an analytical quality control system in a core laboratory.

PubMed

Marques-Garcia, F; Garcia-Codesal, M F; Caro-Narros, M R; Contreras-SanFeliciano, T

2015-01-01

The aim of the clinical laboratory is to provide useful information for screening, diagnosis and monitoring of disease. The laboratory should ensure the quality of extra-analytical and analytical process, based on set criteria. To do this, it develops and implements a system of internal quality control, designed to detect errors, and compare its data with other laboratories, through external quality control. In this way it has a tool to detect the fulfillment of the objectives set, and in case of errors, allowing corrective actions to be made, and ensure the reliability of the results. This article sets out to describe the design and implementation of an internal quality control protocol, as well as its periodical assessment intervals (6 months) to determine compliance with pre-determined specifications (Stockholm Consensus(1)). A total of 40 biochemical and 15 immunochemical methods were evaluated using three different control materials. Next, a standard operation procedure was planned to develop a system of internal quality control that included calculating the error of the analytical process, setting quality specifications, and verifying compliance. The quality control data were then statistically depicted as means, standard deviations, and coefficients of variation, as well as systematic, random, and total errors. The quality specifications were then fixed and the operational rules to apply in the analytical process were calculated. Finally, our data were compared with those of other laboratories through an external quality assurance program. The development of an analytical quality control system is a highly structured process. This should be designed to detect errors that compromise the stability of the analytical process. The laboratory should review its quality indicators, systematic, random and total error at regular intervals, in order to ensure that they are meeting pre-determined specifications, and if not, apply the appropriate corrective actions. Copyright © 2015 SECA. Published by Elsevier Espana. All rights reserved.

Cryogenic performance of a cryocooler-cooled superconducting undulator

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fuerst, J. D.; Doose, C.; Hasse, Q.

2014-01-29

A cryocooler-cooled superconducting undulator has been installed and operated with beam at the Advanced Photon Source (APS) at Argonne National Laboratory (ANL). The device consists of a dual-core 42-pole magnet structure that is cooled to 4.2 K with a system of four cryocoolers operating in a zero-boil-off configuration. This effort represents the culmination of a development program to establish concept feasibility and evaluate cryostat design and cryocooler-based refrigeration. Cryostat performance is described including cool-down/warm-up, steady-state operation, cooling margin, and the impact of beam during operation in the APS storage ring. Plans for future devices with longer magnets, which will incorporatemore » lessons learned from the development program, are also discussed.« less

Laboratory evaluation of alcohol safety interlock systems. Volume 2 : instrument screening experiments

DOT National Transportation Integrated Search

1974-01-01

The report contains the results of an experimental and analytical evaluation of instruments and techniques designed to prevent an intoxicated driver from operating his automobile. The prototype 'Alcohol Safety Interlock Systems' tested were developed...

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

Monsanto Research Corporation operates Mound Laboratory, a government-owned facility of the U.S. Energy Research and Development Administration, at Miamisburg, Ohio. Mound Laboratory is an integrated, research, development, and production facility performing work in support of ERDA weapon and nonweapon programs with emphasis on explosive and nuclear technology. Mound Laboratory originated as a technical organization in 1943 when Monsanto Chemical Company was requested to accept responsibility for determining the chemical and metallurgical properties of polonium as a project of the Manhattan Engineering District. Work was carried on at Monsanto`s Central Research Department and several satellite units in the Dayton, Ohio area.more » Late in 1945, the Manhattan Engineering District determined that the research, development and production organization established by Monsanto at Dayton should become a permanent facility. A search for a suitable location in early 1946 led to the selection of a 180-acre tract adjacent to Miamisburg, about ten miles (16 km) south of Dayton. Construction of Mound Laboratory, which was named after the Miamisburg Indian Mound adjacent to the site, began in February 1947 and was completed in 1948. The new laboratory was the first permanent facility of the Atomic Energy Commission which had succeeded the Manhattan Engineering District.« less

Development and Use of a Virtual NMR Facility

NASA Astrophysics Data System (ADS)

Keating, Kelly A.; Myers, James D.; Pelton, Jeffrey G.; Bair, Raymond A.; Wemmer, David E.; Ellis, Paul D.

2000-03-01

We have developed a "virtual NMR facility" (VNMRF) to enhance access to the NMR spectrometers in Pacific Northwest National Laboratory's Environmental Molecular Sciences Laboratory (EMSL). We use the term virtual facility to describe a real NMR facility made accessible via the Internet. The VNMRF combines secure remote operation of the EMSL's NMR spectrometers over the Internet with real-time videoconferencing, remotely controlled laboratory cameras, real-time computer display sharing, a Web-based electronic laboratory notebook, and other capabilities. Remote VNMRF users can see and converse with EMSL researchers, directly and securely control the EMSL spectrometers, and collaboratively analyze results. A customized Electronic Laboratory Notebook allows interactive Web-based access to group notes, experimental parameters, proposed molecular structures, and other aspects of a research project. This paper describes our experience developing a VNMRF and details the specific capabilities available through the EMSL VNMRF. We show how the VNMRF has evolved during a test project and present an evaluation of its impact in the EMSL and its potential as a model for other scientific facilities. All Collaboratory software used in the VNMRF is freely available from http://www.emsl.pnl.gov:2080/docs/collab.

NASA's DC-8 flying laboratory seen at sunset after a flight supporting the AirSAR 2004 Mesoamerica campaign

NASA Image and Video Library

2004-03-06

NASA's DC-8 flying laboratory seen at sunset after a flight supporting the AirSAR 2004 Mesoamerica campaign. AirSAR 2004 Mesoamerica is a three-week expedition by an international team of scientists that uses an all-weather imaging tool, called the Airborne Synthetic Aperture Radar (AirSAR) which is located onboard NASA's DC-8 airborne laboratory. Scientists from many parts of the world including NASA's Jet Propulsion Laboratory are combining ground research done in several areas in Central America with NASA's AirSAR technology to improve and expand on the quality of research they are able to conduct. The radar, developed by NASA's Jet Propulsion Laboratory, can penetrate clouds and also collect data at night. Its high-resolution sensors operate at multiple wavelengths and modes, allowing AirSAR to see beneath treetops, through thin sand, and dry snow pack. AirSAR's 2004 campaign is a collaboration of many U.S. and Central American institutions and scientists, including NASA; the National Science Foundation; the Smithsonian Institution; National Geographic; Conservation International; the Organization of Tropical Studies; the Central American Commission for Environment and Development; and the Inter-American Development Bank.

Criticality safety strategy for the Fuel Cycle Facility electrorefiner at Argonne National Laboratory, West

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mariani, R.D.; Benedict, R.W.; Lell, R.M.

1993-09-01

The Integral Fast Reactor being developed by Argonne National Laboratory (ANL) combines the advantages of metal-fueled, liquid-metal-cooled reactors and a closed fuel cycle. Presently, the Fuel Cycle Facility (FCF) at ANL-West in Idaho Falls, Idaho is being modified to recycle spent metallic fuel from Experimental Breeder Reactor II as part of a demonstration project sponsored by the Department of Energy. A key component of the FCF is the electrorefiner (ER) in which the actinides are separated from the fission products. In the electrorefining process, the metal fuel is anodically dissolved into a high-temperature molten salt and refined uranium or uranium/plutoniummore » products are deposited at cathodes. In this report, the criticality safety strategy for the FCF ER is summarized. FCF ER operations and processes formed the basis for evaluating criticality safety and control during actinide metal fuel refining. In order to show criticality safety for the FCF ER, the reference operating conditions for the ER had to be defined. Normal operating envelopes (NOES) were then defined to bracket the important operating conditions. To keep the operating conditions within their NOES, process controls were identified that can be used to regulate the actinide forms and content within the ER. A series of operational checks were developed for each operation that wig verify the extent or success of an operation. The criticality analysis considered the ER operating conditions at their NOE values as the point of departure for credible and incredible failure modes. As a result of the analysis, FCF ER operations were found to be safe with respect to criticality.« less

Virtual Laboratories to Achieve Higher-Order Learning in Fluid Mechanics

NASA Astrophysics Data System (ADS)

Ward, A. S.; Gooseff, M. N.; Toto, R.

2009-12-01

Bloom’s higher-order cognitive skills (analysis, evaluation, and synthesis) are recognized as necessary in engineering education, yet these are difficult to achieve in traditional lecture formats. Laboratory components supplement traditional lectures in an effort to emphasize active learning and provide higher-order challenges, but these laboratories are often subject to the constraints of (a) increasing student enrollment, (b) limited funding for operational, maintenance, and instructional expenses and (c) increasing demands on undergraduate student credit requirements. Here, we present results from a pilot project implementing virtual (or online) laboratory experiences as an alternative to a traditional laboratory experience in Fluid Mechanics, a required third year course. Students and faculty were surveyed to identify the topics that were most difficult, and virtual laboratory and design components developed to supplement lecture material. Each laboratory includes a traditional lab component, requiring student analysis and evaluation. The lab concludes with a design exercise, which imposes additional problem constraints and allows students to apply their laboratory observations to a real-world situation.

DARHT: INTEGRATION OF AUTHORIZATION BASIS REQUIREMENTS AND WORKER SAFETY

DOE Office of Scientific and Technical Information (OSTI.GOV)

D. A. MC CLURE; C. A. NELSON; R. L. BOUDRIE

2001-04-01

This document describes the results of consensus agreements reached by the DARHT Safety Planning Team during the development of the update of the DARHT Safety Analysis Document (SAD). The SAD is one of the Authorization Basis (AB) Documents required by the Department prior to granting approval to operate the DARHT Facility. The DARHT Safety Planning Team is lead by Mr. Joel A. Baca of the Department of Energy Albuquerque Operations Office (DOE/AL). Team membership is drawn from the Department of Energy Albuquerque Operations Office, the Department of Energy Los Alamos Area Office (DOE/LAAO), and several divisions of the Los Alamosmore » National Laboratory. Revision 1 of the DARHT SAD had been written as part of the process for gaining approval to operate the Phase 1 (First Axis) Accelerator. Early in the planning stage for the required update of the SAD for the approval to operate both Phase 1 and Phase 2 (First Axis and Second Axis) DARHT Accelerator, it was discovered that a conflict existed between the Laboratory approach to describing the management of facility and worker safety.« less

Development of a preliminary design of a method to measure the effectiveness of virus exclusion during water process reclamation at zero-G

NASA Technical Reports Server (NTRS)

Fraser, A. S.; Wells, A. F.; Tenoso, H. J.; Linnecke, C. B.

1976-01-01

Organon Diagnostics has developed, under NASA sponsorship, a monitoring system to test the capability of a water recovery system to reject the passage of viruses into the recovered water. In this system, a non-pathogenic marker virus, bacteriophage F2, is fed into the process stream before the recovery unit and the reclaimed water is assayed for its presence. An engineering preliminary design has been performed as a parallel effort to the laboratory development of the marker virus test system. Engineering schematics and drawings present a preliminary instrument design of a fully functional laboratory prototype capable of zero-G operation.

Multi-Mission Simulation and Visualization for Real-Time Telemetry Display, Playback and EDL Event Reconstruction

NASA Technical Reports Server (NTRS)

Pomerantz, M. I.; Lim, C.; Myint, S.; Woodward, G.; Balaram, J.; Kuo, C.

2012-01-01

he Jet Propulsion Laboratory's Entry, Descent and Landing (EDL) Reconstruction Task has developed a software system that provides mission operations personnel and analysts with a real time telemetry-based live display, playback and post-EDL reconstruction capability that leverages the existing high-fidelity, physics-based simulation framework and modern game engine-derived 3D visualization system developed in the JPL Dynamics and Real Time Simulation (DARTS) Lab. Developed as a multi-mission solution, the EDL Telemetry Visualization (ETV) system has been used for a variety of projects including NASA's Mars Science Laboratory (MSL), NASA'S Low Density Supersonic Decelerator (LDSD) and JPL's MoonRise Lunar sample return proposal.

GEOS. User Tutorials

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fu, Pengchen; Settgast, Randolph R.; Johnson, Scott M.

2014-12-17

GEOS is a massively parallel, multi-physics simulation application utilizing high performance computing (HPC) to address subsurface reservoir stimulation activities with the goal of optimizing current operations and evaluating innovative stimulation methods. GEOS enables coupling of di erent solvers associated with the various physical processes occurring during reservoir stimulation in unique and sophisticated ways, adapted to various geologic settings, materials and stimulation methods. Developed at the Lawrence Livermore National Laboratory (LLNL) as a part of a Laboratory-Directed Research and Development (LDRD) Strategic Initiative (SI) project, GEOS represents the culmination of a multi-year ongoing code development and improvement e ort that hasmore » leveraged existing code capabilities and sta expertise to design new computational geosciences software.« less

DOE Office of Scientific and Technical Information (OSTI.GOV)

Greenwood, L. R.; Cantaloub, M. G.; Burnett, J. L.

PNNL has developed two low-background gamma-ray spectrometers in a new shallow underground laboratory, thereby significantly improving its ability to detect low levels of gamma-ray emitting fission or activation products in airborne particulate in samples from the IMS (International Monitoring System). Furthermore, the combination of cosmic veto panels, dry nitrogen gas to reduce radon and low background shielding results in a reduction of the background count rate by about a factor of 100 compared to detectors operating above ground at our laboratory.

Statement of Work Electrical Energy Storage System Installation at Sandia National Laboratories.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Schenkman, Benjamin L.

2017-03-01

Sandia is seeking to procure a 1 MWh energy storage system. It will be installed at the existing Energy Storage Test Pad, which is located at Sandia National Laboratories in Albuquerque, New Mexico. This energy storage system will be a daily operational system, but will also be used as a tool in our Research and development work. The system will be part of a showcase of Sandia distributed energy technologies viewed by many distinguished delegates.

Integrated Studies of Electric Propulsion Engines during Flights in the Earth's Ionosphere

NASA Astrophysics Data System (ADS)

Marov, M. Ya.; Filatyev, A. S.

2018-03-01

Fifty years ago, on October 1, 1966, the first Yantar satellite laboratory with a gas plasma-ion electric propulsion was launched into orbit as part of the Yantar Soviet space program. In 1966-1971, the program launched a total of four laboratories with thrusters operating on argon, nitrogen, and air with jet velocities of 40, 120, and 140 km/s, respectively. These space experiments were the first to demonstrate the long-term stable operation of these thrusters, which exceed chemical rocket engines in specific impulse by an order of magnitude and provide effective jet charge compensation, under the conditions of a real flight at altitudes of 100-400 km. In this article, we have analyzed the potential modern applications of the scientific results obtained by the Yantar space program for the development of air-breathing electric propulsion that ensure the longterm operation of spacecraft in very low orbits.

Laboratory on legs: an architecture for adjustable morphology with legged robots

NASA Astrophysics Data System (ADS)

Haynes, G. Clark; Pusey, Jason; Knopf, Ryan; Johnson, Aaron M.; Koditschek, Daniel E.

2012-06-01

For mobile robots, the essential units of actuation, computation, and sensing must be designed to fit within the body of the robot. Additional capabilities will largely depend upon a given activity, and should be easily reconfigurable to maximize the diversity of applications and experiments. To address this issue, we introduce a modular architecture originally developed and tested in the design and implementation of the X-RHex hexapod that allows the robot to operate as a mobile laboratory on legs. In the present paper we will introduce the specification, design and very earliest operational data of Canid, an actively driven compliant-spined quadruped whose completely different morphology and intended dynamical operating point are nevertheless built around exactly the same "Lab on Legs" actuation, computation, and sensing infrastructure. We will review as well, more briefly a second RHex variation, the XRL platform, built using the same components.

Autonomous Payload Operations Onboard the International Space Station

NASA Technical Reports Server (NTRS)

Stetson, Howard K.; Deitsch, David K.; Cruzen, Craig A.; Haddock, Angie T.

2007-01-01

Operating the International Space Station (ISS) involves many complex crew tended, ground operated and combined systems. Over the life of the ISS program, it has become evident that by having automated and autonomous systems on board, more can be accomplished and at the same time reduce the workload of the crew and ground operators. Engineers at the National Aeronautics and Space Administration's (NASA) Marshall Space Flight Center in Huntsville Alabama, working in collaboration with The Charles Stark Draper Laboratory have developed an autonomous software system that uses the Timeliner User Interface Language and expert logic to continuously monitor ISS payload systems, issue commands and signal ground operators as required. This paper describes the development history of the system, its concept of operation and components. The paper also discusses the testing process as well as the facilities used to develop the system. The paper concludes with a description of future enhancement plans for use on the ISS as well as potential applications to Lunar and Mars exploration systems.

Development of advanced strain diagnostic techniques for reactor environments.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fleming, Darryn D.; Holschuh, Thomas Vernon,; Miller, Timothy J.

2013-02-01

The following research is operated as a Laboratory Directed Research and Development (LDRD) initiative at Sandia National Laboratories. The long-term goals of the program include sophisticated diagnostics of advanced fuels testing for nuclear reactors for the Department of Energy (DOE) Gen IV program, with the future capability to provide real-time measurement of strain in fuel rod cladding during operation in situ at any research or power reactor in the United States. By quantifying the stress and strain in fuel rods, it is possible to significantly improve fuel rod design, and consequently, to improve the performance and lifetime of the cladding.more » During the past year of this program, two sets of experiments were performed: small-scale tests to ensure reliability of the gages, and reactor pulse experiments involving the most viable samples in the Annulated Core Research Reactor (ACRR), located onsite at Sandia. Strain measurement techniques that can provide useful data in the extreme environment of a nuclear reactor core are needed to characterize nuclear fuel rods. This report documents the progression of solutions to this issue that were explored for feasibility in FY12 at Sandia National Laboratories, Albuquerque, NM.« less

Theme: Land Laboratories--Urban Settings, Liability, Natural Resources Labs.

ERIC Educational Resources Information Center

Whaley, David, Ed.; And Others

1994-01-01

Includes "With a Little Imagination"; "From Fallow to Fertile"; "Operating a School Enterprise in Agriculture"; "Using a Nontraditional Greenhouse to Enhance Lab Instruction"; "Risk Management for Liability in Operating Land Laboratories"; "Working Land and Water Laboratory for Natural…

Automated solar panel assembly line

NASA Technical Reports Server (NTRS)

Somberg, H.

1981-01-01

The initial stage of the automated solar panel assembly line program was devoted to concept development and proof of approach through simple experimental verification. In this phase, laboratory bench models were built to demonstrate and verify concepts. Following this phase was machine design and integration of the various machine elements. The third phase was machine assembly and debugging. In this phase, the various elements were operated as a unit and modifications were made as required. The final stage of development was the demonstration of the equipment in a pilot production operation.

Development of a helmet-mounted PLZT thermal/flash protection system. [Protective goggles

DOE Office of Scientific and Technical Information (OSTI.GOV)

Harris, J.O. Jr.; Cutchen, J.T.; Pfoff, B.J.

1976-01-01

Sandia Laboratories is developing PLZT thermal/flash protective devices (TFPD's) goggles to prevent exposure and resultant eye damage from nuclear weapon detonations. The primary emphasis of the present program is to transfer technology and establish production capability for helmet-mounted PLZT/TFPD goggles for USAF flight crews, with a non-helmet-mounted configuration to follow. The first production units are anticipated in the fall of 1977. The operating principles of the PLZT/TFPD goggle device are briefly outlined, and the device configuration and operational characteristics are described.

Developing an SSAC Self-Assessment Tool for Operators and Regulators

DOE Office of Scientific and Technical Information (OSTI.GOV)

Frazar, Sarah L.; Innes-Jones, Gemma; Hamilton, Ian

Enabling an SSAC to understand why it is performing inefficiently can help it allocate resources more effectively to better support IAEA safeguards implementation. In collaboration with international consulting firm, Environmental Resources Management (ERM) and a U.S. based nuclear fuel cycle facility, the Pacific Northwest National Laboratory (PNNL) has been developing a framework for a future self-assessment tool for nuclear operators and regulators. This paper will describe the effort to date, with particular emphasis on the steps the team took to align the framework with relevant IAEA self-assessment tools.

Laboratory testing under managed care dominance in the USA

PubMed Central

Takemura, Y; Beck, J

2001-01-01

The uncontrolled escalation of total health care expenditure despite the government's endeavours during the past decades in the USA had led to the rapid infiltration of managed care organisations (MCOs). Traditional hospital based laboratories have been placed in a crucial situation with the advent of the managed care era. A massive reduction of in house testing urged them to develop strategies against financial difficulty. Consolidation and networking, participation in the outreach testing market, and emphasis on point of care/satellite laboratory testing in non-traditional, ambulatory settings are major strategies for the survival of hospital laboratories. Several physicians' office laboratories (POLS) have closed their doors in response both to regulatory restrictions imposed by the Clinical Laboratory Improvement Amendments of 1988 and to managed care infiltration. It seems likely that POLs and hospital laboratories will continue to reduce test volumes, whereas commercial reference laboratories will thrive through contracting with MCOs. In the current climate of managed care dominance in the USA, clinical laboratories are changing their basic operation focus and mission in response to the aggressively changing landscape. Key Words: laboratory testing • managed care organisations • survival strategies PMID:11215291

Advanced Stirling Convertor Control Unit Testing at NASA Glenn Research Center in the Radioisotope Power Systems System Integration Laboratory

NASA Technical Reports Server (NTRS)

Dugala, Gina M.; Taylor, Linda M.; Kussmaul, Michael; Casciani, Michael; Brown, Gregory; Wiser, Joel

2017-01-01

Future NASA missions could include establishing Lunar or Martian base camps, exploring Jupiters moons and travelling beyond where generating power from sunlight may be limited. Radioisotope Power Systems (RPS) provide a dependable power source for missions where inadequate sunlight or operational requirements make other power systems impractical. Over the past decade, NASA Glenn Research Center (GRC) has been supporting the development of RPSs. The Advanced Stirling Radioisotope Generator (ASRG) utilized a pair of Advanced Stirling Convertors (ASC). While flight development of the ASRG has been cancelled, much of the technology and hardware continued development and testing to guide future activities. Specifically, a controller for the convertor(s) is an integral part of a Stirling-based RPS. For the ASRG design, the controller maintains stable operation of the convertors, regulates the alternating current produced by the linear alternator of the convertor, provides a specified direct current output voltage for the spacecraft, synchronizes the piston motion of the two convertors in order to minimize vibration as well as manage and maintain operation with a stable piston amplitude and hot end temperature. It not only provides power to the spacecraft but also must regulate convertor operation to avoid damage to internal components and maintain safe thermal conditions after fueling. Lockheed Martin Coherent Technologies has designed, developed and tested an Engineering Development Unit (EDU) Advanced Stirling Convertor Control Unit (ACU) to support this effort. GRC used the ACU EDU as part of its non-nuclear representation of a RPS which also consists of a pair of Dual Advanced Stirling Convertor Simulator (DASCS), and associated support equipment to perform a test in the Radioisotope Power Systems System Integration Laboratory (RSIL). The RSIL was designed and built to evaluate hardware utilizing RPS technology. The RSIL provides insight into the electrical interactions between as many as 3 radioisotope power generators, associated control strategies, and typical electric system loads. The first phase of testing included a DASCS which was developed by Johns Hopkins UniversityApplied Physics Laboratory and simulates the operation and electrical behavior of a pair of ASCs in real time via a combination of hardware and software. Testing included the following spacecraft electrical energy storage configurations: capacitive, battery, and supercapacitor. Testing of the DASCS and ACU in each energy storage configuration included simulation of a typical mission profile, and transient voltage and current data during load turn-on/turn-off. Testing for these devices also included the initiation of several system faults such as short circuits, electrical bus over-voltage, under-voltage and a dead bus recovery to restore normal power operations. The goal of this testing was to verify operation of the ACU(s) when connected to a spacecraft electrical bus.

Site Environmental Report for Calendar Year 2009. DOE Operations at The Boeing Company Santa Susana Field Laboratory, Area IV

DOE Office of Scientific and Technical Information (OSTI.GOV)

Liu, Ning; Rutherford, Phil; Amar, Ravnesh

2010-09-01

This Annual Site Environmental Report (ASER) for 2009 describes the environmental conditions related to work performed for the Department of Energy (DOE) at Area IV of Boeing’s Santa Susana Field Laboratory (SSFL). The Energy Technology Engineering Center (ETEC), a government-owned, company-operated test facility, was located in Area IV. The operations in Area IV included development, fabrication, and disassembly of nuclear reactors, reactor fuel, and other radioactive materials. Other activities in the area involved the operation of large-scale liquid metal facilities that were used for testing non-nuclear liquid metal fast breeder reactor components. All nuclear work was terminated in 1988, andmore » all subsequent radiological work has been directed toward decontamination and decommissioning (D&D) of the former nuclear facilities and their associated sites. Liquid metal research and development ended in 2002. Since May 2007, the D&D operations in Area IV have been suspended by the DOE, but the environmental monitoring and characterization programs have continued. Results of the radiological monitoring program for the calendar year 2009 continue to indicate that there are no significant releases of radioactive material from Area IV of SSFL. All potential exposure pathways are sampled and/or monitored, including air, soil, surface water, groundwater, direct radiation, transfer of property (land, structures, waste), and recycling.« less

Site Environmental Report for Calendar Year 2010. DOE Operations at The Boeing Company Santa Susana Field Laboratory, Area IV

DOE Office of Scientific and Technical Information (OSTI.GOV)

Liu, Ning; Rutherford, Phil; Amar, Ravnesh

2011-09-01

This Annual Site Environmental Report (ASER) for 2010 describes the environmental conditions related to work performed for the Department of Energy (DOE) at Area IV of Boeing’s Santa Susana Field Laboratory (SSFL). The Energy Technology Engineering Center (ETEC), a government-owned, company-operated test facility, was located in Area IV. The operations in Area IV included development, fabrication, and disassembly of nuclear reactors, reactor fuel, and other radioactive materials. Other activities in the area involved the operation of large-scale liquid metal facilities that were used for testing non-nuclear liquid metal fast breeder reactor components. All nuclear work was terminated in 1988, andmore » all subsequent radiological work has been directed toward decontamination and decommissioning (D&D) of the former nuclear facilities and their associated sites. Liquid metal research and development ended in 2002. Since May 2007, the D&D operations in Area IV have been suspended by the DOE, but the environmental monitoring and characterization programs have continued. Results of the radiological monitoring program for the calendar year 2010 continue to indicate that there are no significant releases of radioactive material from Area IV of SSFL. All potential exposure pathways are sampled and/or monitored, including air, soil, surface water, groundwater, direct radiation, transfer of property (land, structures, waste), and recycling.« less

The changing role of the medical technologist from technologist to information specialist.

PubMed

Miller, W G

2000-01-01

Pathology laboratory services are dependent on the laboratory information system (LIS) to organize the work, manage the operation, and communicate the results for effective laboratory medicine. For maximum efficiency, staffing for the LIS should be an integral component of laboratory operations and is facilitated by a two-tier structure. A core LIS staff provides system support and continuous services. A group of bench medical technologists have multitasking responsibilities, including LIS support for a specific laboratory work area. The two components form a team that uses staff efficiently to provide ongoing operational services and flexibility for problem solving and new functionality implementation.

Hanford Laboratories Operation monthly activities report, September 1960

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1960-10-15

This is the monthly report for the Hanford Laboratories Operation, October, 1960. Metallurgy, reactor fuels, chemistry, dosimetry, separation processes, reactor technology, financial activities, visits, biology operation, physics and instrumentation research, and employee relations are discussed.

Hanford Laboratories Operation monthly activities report, November 1962

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1962-12-14

This is the monthly report for the Hanford Laboratories Operation, November 1962. Metallurgy, reactor fuels, chemistry, dosimetry, separation processes, reactor technology, financial activities, visits, biology operation, physics and instrumentation research, and employee relations are discussed.

Electromagnetic propulsion for spacecraft

NASA Technical Reports Server (NTRS)

Myers, Roger M.

1993-01-01

Three electromagnetic propulsion technologies, solid propellant pulsed plasma thrusters (PPT), magnetoplasmadynamic (MPD) thrusters, and pulsed inductive thrusters (PIT) have been developed for application to auxiliary and primary spacecraft propulsion. Both the PPT and MPD thrusters have been flown in space, though only PPTs have been used on operational satellites. The performance of operational PPTs is quite poor, providing only about 8 percent efficiency at about 1000 sec specific impulse. Laboratory PPTs yielding 34 percent efficiency at 5170 sec specific impulse have been demonstrated. Laboratory MPD thrusters have been demonstrated with up to 70 percent efficiency and 7000 sec specific impulse. Recent PIT performance measurements using ammonia and hydrazine propellants are extremely encouraging, reaching 50 percent efficiency for specific impulses between 4000 and 8000 sec.

Study and Development of an Air Conditioning System Operating on a Magnetic Heat Pump Cycle

NASA Technical Reports Server (NTRS)

Wang, Pao-Lien

1991-01-01

This report describes the design of a laboratory scale demonstration prototype of an air conditioning system operating on a magnetic heat pump cycle. Design parameters were selected through studies performed by a Kennedy Space Center (KSC) System Simulation Computer Model. The heat pump consists of a rotor turning through four magnetic fields that are created by permanent magnets. Gadolinium was selected as the working material for this demonstration prototype. The rotor was designed to be constructed of flat parallel disks of gadolinium with very little space in between. The rotor rotates in an aluminum housing. The laboratory scale demonstration prototype is designed to provide a theoretical Carnot Cycle efficiency of 62 percent and a Coefficient of Performance of 16.55.

Site Environmental Report for Calendar Year 2005. DOE Operations at The Boeing Company, Santa Susana Field Laboratory, Area IV

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

2006-09-30

This annual report describes the environmental monitoring programs related to the Department of Energy’s (DOE) activities at the Santa Susana Field Laboratory (SSFL) facility located in Ventura County, California during 2005. Part of the SSFL facility, known as Area IV, had been used for DOE’s activities since the 1950s. A broad range of energy related research and development (R&D) projects, including nuclear technologies projects, was conducted at the site. All the nuclear R&D operations in Area IV ceased in 1988. Current efforts are directed toward decontamination and decommissioning (D&D) of the former nuclear facilities and closure of facilities used formore » liquid metal research.« less

EXXON donor solvent coal liquefaction process

NASA Technical Reports Server (NTRS)

Epperly, W. R.; Swabb, L. E., Jr.; Tauton, J. W.

1978-01-01

A solvent coal liquefaction process to produce low-sulfur liquid products from a wide range of coals is described. An integrated program of laboratory and engineering research and development in conjunction with operation of a 250 T/D pilot plant is discussed.

Saturn S-2 Automatic Software System /SASS/

NASA Technical Reports Server (NTRS)

Parker, P. E.

1967-01-01

SATURN S-2 Automatic Software System /SASS/ was designed and implemented to aid SATURN S-2 program development and to increase the overall operating efficiency within the S-2 data laboratory. This program is written in FORTRAN 2 for SDS 920 computers.

Laboratory evaluation of alcohol safety interlock systems. Volume 3 : instrument performance at high BAL

DOT National Transportation Integrated Search

1974-01-01

This report contains the results of an experimental and analytical evaluation of instruments and techniques designed to prevent an intoxicated driver from operating his automobile. The prototype 'Alcohol Safety Interlock Systems' tested were develope...

About the Frederick National Laboratory for Cancer Research | FNLCR Staging

Cancer.gov

The Frederick National Lab is a Federally Funded Research and Development Center (FFRDC) sponsored by the National Cancer Institute (NCI) and operated by Leidos Biomedical Research, Inc. The lab addresses some of the most urgent and intractable probl

Enhanced control & sensing for the REMOTEC ANDROS Mk VI robot. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Spelt, P.F.; Harvey, H.W.

1997-08-01

This Cooperative Research and Development Agreement (CRADA) between Lockheed Marietta Energy Systems, Inc., and REMOTEC, Inc., explored methods of providing operator feedback for various work actions of the ANDROS Mk VI teleoperated robot. In a hazardous environment, an extremely heavy workload seriously degrades the productivity of teleoperated robot operators. This CRADA involved the addition of computer power to the robot along with a variety of sensors and encoders to provide information about the robot`s performance in and relationship to its environment. Software was developed to integrate the sensor and encoder information and provide control input to the robot. ANDROS Mkmore » VI robots are presently used by numerous electric utilities to perform tasks in reactors where substantial exposure to radiation exists, as well as in a variety of other hazardous environments. Further, this platform has potential for use in a number of environmental restoration tasks, such as site survey and detection of hazardous waste materials. The addition of sensors and encoders serves to make the robot easier to manage and permits tasks to be done more safely and inexpensively (due to time saved in the completion of complex remote tasks). Prior research on the automation of mobile platforms with manipulators at Oak Ridge National Laboratory`s Center for Engineering Systems Advanced Research (CESAR, B&R code KC0401030) Laboratory, a BES-supported facility, indicated that this type of enhancement is effective. This CRADA provided such enhancements to a successful working teleoperated robot for the first time. Performance of this CRADA used the CESAR laboratory facilities and expertise developed under BES funding.« less

A Dynamic Infrastructure for Interconnecting Disparate ISR/ISTAR Assets (the ITA Sensor Fabric)

DTIC Science & Technology

2009-07-01

areas of sensor identification, classification, interoperability and sensor data sharing, dissemination and consumability. This paper presents the ITA...sensors in the area of operations. This paper also presents a use case scenario developed in partnership with the U.S. Army Research Laboratory (ARL) and... paper we describe the Fabric, and its application to a simulated representative coalition operation scenario. The Fabric spans the network from the

A FEASIBILITY STUDY TO INVESTIGATE THE INSTRUMENTATION, ESTABLISHMENT, AND OPERATION OF A LEARNING LABORATORY FOR HARD-OF-HEARING CHILDREN, FINAL REPORT.

ERIC Educational Resources Information Center

STEPP, ROBERT E.

TEN CHILDREN AGED 5-8 WERE SELECTED TO TEST A SELF-INSTRUCTIONAL, SELF-OPERATING SYSTEM TO DEVELOP LIPREADING SKILLS. THEIR HEARING DEFICIENCY RANGED FROM HARD OF HEARING TO PROFOUNDLY DEAF. THE SYSTEM CONSISTED OF THREE STUDY CARRELS, AN 8-MM CARTRIDGE-LOADING SOUND MOTION PICTURE PROJECTOR, AND AN OBSERVATION BOOTH UTILIZING A ONE-WAY MIRROR.…

Optimizing Hydropower Day-Ahead Scheduling for the Oroville-Thermalito Project

NASA Astrophysics Data System (ADS)

Veselka, T. D.; Mahalik, M.

2012-12-01

Under an award from the U.S. Department of Energy, Office of Energy Efficiency and Renewable Energy, Water Power Program, a team of national laboratories is developing and demonstrating a suite of advanced, integrated analytical tools to assist managers and planners increase hydropower resources while enhancing the environment. As part of the project, Argonne National Laboratory is developing the Conventional Hydropower Energy and Environmental Systems (CHEERS) model to optimize day-ahead scheduling and real-time operations. We will present the application of CHEERS to the Oroville-Thermalito Project located in Northern California. CHEERS will aid California Department of Water Resources (CDWR) schedulers in making decisions about unit commitments and turbine-level operating points using a system-wide approach to increase hydropower efficiency and the value of power generation and ancillary services. The model determines schedules and operations that are constrained by physical limitations, characteristics of plant components, operational preferences, reliability, and environmental considerations. The optimization considers forebay and afterbay implications, interactions between cascaded power plants, turbine efficiency curves and rough zones, and operator preferences. CHEERS simultaneously considers over time the interactions among all CDWR power and water resources, hydropower economics, reservoir storage limitations, and a set of complex environmental constraints for the Thermalito Afterbay and Feather River habitats. Power marketers, day-ahead schedulers, and plant operators provide system configuration and detailed operational data, along with feedback on model design and performance. CHEERS is integrated with CDWR data systems to obtain historic and initial conditions of the system as the basis from which future operations are then optimized. Model results suggest alternative operational regimes that improve the value of CDWR resources to the grid while enhancing the environment and complying with water delivery obligations for non-power uses.

Advanced optical blade tip clearance measurement system

NASA Technical Reports Server (NTRS)

Ford, M. J.; Honeycutt, R. E.; Nordlund, R. E.; Robinson, W. W.

1978-01-01

An advanced electro-optical system was developed to measure single blade tip clearances and average blade tip clearances between a rotor and its gas path seal in an operating gas turbine engine. This system is applicable to fan, compressor, and turbine blade tip clearance measurement requirements, and the system probe is particularly suitable for operation in the extreme turbine environment. A study of optical properties of blade tips was conducted to establish measurement system application limitations. A series of laboratory tests was conducted to determine the measurement system's operational performance characteristics and to demonstrate system capability under simulated operating gas turbine environmental conditions. Operational and environmental performance test data are presented.

Initial Investigations of Controller Tools and Procedures for Schedule-Based Arrival Operations with Mixed Flight-Deck Interval Management Equipage

NASA Technical Reports Server (NTRS)

Callantine, Todd J.; Cabrall, Christopher; Kupfer, Michael; Omar, Faisal G.; Prevot, Thomas

2012-01-01

NASA?s Air Traffic Management Demonstration-1 (ATD-1) is a multi-year effort to demonstrate high-throughput, fuel-efficient arrivals at a major U.S. airport using NASA-developed scheduling automation, controller decision-support tools, and ADS-B-enabled Flight-Deck Interval Management (FIM) avionics. First-year accomplishments include the development of a concept of operations for managing scheduled arrivals flying Optimized Profile Descents with equipped aircraft conducting FIM operations, and the integration of laboratory prototypes of the core ATD-1 technologies. Following each integration phase, a human-in-the-loop simulation was conducted to evaluate and refine controller tools, procedures, and clearance phraseology. From a ground-side perspective, the results indicate the concept is viable and the operations are safe and acceptable. Additional training is required for smooth operations that yield notable benefits, particularly in the areas of FIM operations and clearance phraseology.

An Overview of Current Capabilities and Research Activities in the Airspace Operations Laboratory at NASA Ames Research Center

NASA Technical Reports Server (NTRS)

Prevot, Thomas; Smith, Nancy M.; Palmer, Everett; Callantine, Todd; Lee, Paul; Mercer, Joey; Homola, Jeff; Martin, Lynne; Brasil, Connie; Cabrall, Christopher

2014-01-01

The Airspace Operations Laboratory at NASA Ames conducts research to provide a better understanding of roles, responsibilities, and requirements for human operators and automation in future air traffic management (ATM) systems. The research encompasses developing, evaluating, and integrating operational concepts and technologies for near-, mid-, and far-term air traffic operations. Current research threads include efficient arrival operations, function allocation in separation assurance and efficient airspace and trajectory management. The AOL has developed powerful air traffic simulation capabilities, most notably the Multi Aircraft Control System (MACS) that is used for many air traffic control simulations at NASA and its partners in government, academia and industry. Several additional NASA technologies have been integrated with the AOL's primary simulation capabilities where appropriate. Using this environment, large and small-scale system-level evaluations can be conducted to help make near-term improvements and transition NASA technologies to the FAA, such as the technologies developed under NASA's Air Traffic Management Demonstration-1 (ATD-1). The AOL's rapid prototyping and flexible simulation capabilities have proven a highly effective environment to progress the initiation of trajectory-based operations and support the mid-term implementation of NextGen. Fundamental questions about accuracy requirements have been investigated as well as realworld problems on how to improve operations in some of the most complex airspaces in the US. This includes using advanced trajectory-based operations and prototype tools for coordinating arrivals to converging runways at Newark airport and coordinating departures and arrivals in the San Francisco and the New York metro areas. Looking beyond NextGen, the AOL has started exploring hybrid human/automation control strategies as well as highly autonomous operations in the air traffic control domain. Initial results indicate improved capacity, low operator workload, good situation awareness and acceptability for controllers teaming with autonomous air traffic systems. While much research and development needs to be conducted to make such concepts a reality, these approaches have the potential to truly transform the airspace system towards increased mobility, safe and efficient growth in global operations and enabling many of the new vehicles and operations that are expected over the next decades. This paper describes how the AOL currently contributes to the ongoing air transportation transformation.

Translational Partnership Development Lead | Center for Cancer Research

Cancer.gov

PROGRAM DESCRIPTION The Frederick National Laboratory for Cancer Research (FNLCR) is a Federally Funded Research and Development Center operated by Leidos Biomedical Research, Inc on behalf of the National Cancer Institute (NCI). The staff of FNLCR support the NCI’s mission in the fight against cancer and HIV/AIDS. Currently we are seeking a Translational Partnership

Development of USPS Laboratory and pilot-scale testing protocols

Treesearch

Carl Houtman; Nancy Ross Sutherland; David Bormett; Donald Donermeyer

2000-01-01

The ultimate goal of the US Postal Service (USPS) Environmentally Benign Stamp Program is to develop stamp adhesives that can be removed by unit operations found in recycling mills. The maintenance of final product quality specifications for a recycling mill while loading the feedstock with a significant quantity of adhesive is the criterion for success of this program...

Development of an Augmented Reality Game to Teach Abstract Concepts in Food Chemistry

ERIC Educational Resources Information Center

Crandall, Philip G.; Engler, Robert K.; Beck, Dennis E.; Killian, Susan A.; O'Bryan, Corliss A.; Jarvis, Nathan; Clausen, Ed

2015-01-01

One of the most pressing issues for many land grant institutions is the ever increasing cost to build and operate wet chemistry laboratories. A partial solution is to develop computer-based teaching modules that take advantage of animation, web-based or off-campus learning experiences directed at engaging students' creative experiences. We…

Nevada Renewable Energy Training Project: Geothermal Power Plant Operators

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jim, Nichols

2014-04-29

The purpose of this project was to develop and institute a training program for certified geothermal power plant operators (GPO). An advisory board consisting of subject matter experts from the geothermal energy industry and academia identified the critical skill sets required for this profession. A 34-credit Certificate of Achievement (COA), Geothermal Power Plant Operator, was developed using eight existing courses and developing five new courses. Approval from the Nevada System of Higher Education Board of Regents was obtained. A 2,400 sq. ft. geothermal/fluid mechanics laboratory and a 3,000 sq. ft. outdoor demonstration laboratory were constructed for hands-on training. Students alsomore » participated in field trips to geothermal power plants in the region. The majority of students were able to complete the program in 2-3 semesters, depending on their level of math proficiency. Additionally the COA allowed students to continue to an Associate of Applied Science (AAS), Energy Technologies with an emphasis in Geothermal Energy (26 additional credits), if they desired. The COA and AAS are stackable degrees, which provide students with an ongoing career pathway. Articulation agreements with other NSHE institutions provide students with additional opportunities to pursue a Bachelor of Applied Science in Management or Instrumentation. Job placement for COA graduates has been excellent.« less

Supply chain management in the clinical laboratory.

PubMed

McHugh, Thomas M

2006-01-31

Between 15 and 45 percent of a clinical laboratory's operating budget is spent on supplies. Given the size of this expenditure, laboratory managers must pay close attention to the supply chain and develop effective strategies to manage their inventory. Areas that need analysis include the carrying cost of supplies, the cost to generate a purchase order, methods to efficiently count supplies on hand, processes to ensure that lot number items are used before their expiration, and detailed analysis of the inventory. At the University of California-San Francisco Medical Center, we investigated options to manage our inventory and implemented a computerized system. The system required modifications to existing practices, which initially seemed unwieldy. However, after a relatively short learning curve, the improvement to operations has been significant, with a reduction in wasted reagents, fewer staff hours used to count supplies, and the ability to provide prompt analysis of the inventory for audits and discussions with administration. Focusing on the supply chain has allowed us to reduce inventory expenses by approximately 8 percent, reduce waste, given us a more focused understanding of our operations, and provided us with the ability to analyze our inventory easily.

A method for developing outcome measures in the clinical laboratory.

PubMed

Jones, J

1996-01-01

Measuring and reporting outcomes in health care is becoming more important for quality assessment, utilization assessment, accreditation standards, and negotiating contracts in managed care. How does one develop an outcome measure for the laboratory to assess the value of the services? A method is described which outlines seven steps in developing outcome measures for a laboratory service or process. These steps include the following: 1. Identify the process or service to be monitored for performance and outcome assessment. 2. If necessary, form an multidisciplinary team of laboratory staff, other department staff, physicians, and pathologists. 3. State the purpose of the test or service including a review of published data for the clinical pathological correlation. 4. Prepare a process cause and effect diagram including steps critical to the outcome. 5. Identify key process variables that contribute to positive or negative outcomes. 6. Identify outcome measures that are not process measures. 7. Develop an operational definition, identify data sources, and collect data. Examples, including a process cause and effect diagram, process variables, and outcome measures, are given using the Therapeutic Drug Monitoring service (TDM). A summary of conclusions and precautions for outcome measurement is then provided.

Manufacturing information system

NASA Astrophysics Data System (ADS)

Allen, D. K.; Smith, P. R.; Smart, M. J.

1983-12-01

The size and cost of manufacturing equipment has made it extremely difficult to perform realistic modeling and simulation of the manufacturing process in university research laboratories. Likewise the size and cost factors, coupled with many uncontrolled variables of the production situation has even made it difficult to perform adequate manufacturing research in the industrial setting. Only the largest companies can afford manufacturing research laboratories; research results are often held proprietary and seldom find their way into the university classroom to aid in education and training of new manufacturing engineers. It is the purpose for this research to continue the development of miniature prototype equipment suitable for use in an integrated CAD/CAM Laboratory. The equipment being developed is capable of actually performing production operations (e.g. drilling, milling, turning, punching, etc.) on metallic and non-metallic workpieces. The integrated CAD/CAM Mini-Lab is integrating high resolution, computer graphics, parametric design, parametric N/C parts programmings, CNC machine control, automated storage and retrieval, with robotics materials handling. The availability of miniature CAD/CAM laboratory equipment will provide the basis for intensive laboratory research on manufacturing information systems.

Analysis of Carbamate Pesticides: Validation of Semi-Volatile Analysis by HPLC-MS/MS by EPA Method MS666

DOE Office of Scientific and Technical Information (OSTI.GOV)

Owens, J; Koester, C

The Environmental Protection Agency's (EPA) Region 5 Chicago Regional Laboratory (CRL) developed a method for analysis of aldicarb, bromadiolone, carbofuran, oxamyl, and methomyl in water by high performance liquid chromatography tandem mass spectrometry (HPLC-MS/MS), titled Method EPA MS666. This draft standard operating procedure (SOP) was distributed to multiple EPA laboratories and to Lawrence Livermore National Laboratory, which was tasked to serve as a reference laboratory for EPA's Environmental Reference Laboratory Network (ERLN) and to develop and validate analytical procedures. The primary objective of this study was to validate and verify the analytical procedures described in MS666 for analysis of carbamatemore » pesticides in aqueous samples. The gathered data from this validation study will be used to: (1) demonstrate analytical method performance; (2) generate quality control acceptance criteria; and (3) revise the SOP to provide a validated method that would be available for use during a homeland security event. The data contained in this report will be compiled, by EPA CRL, with data generated by other EPA Regional laboratories so that performance metrics of Method EPA MS666 can be determined.« less

Analysis of Ethanolamines: Validation of Semi-Volatile Analysis by HPLC-MS/MS by EPA Method MS888

DOE Office of Scientific and Technical Information (OSTI.GOV)

Owens, J; Vu, A; Koester, C

The Environmental Protection Agency's (EPA) Region 5 Chicago Regional Laboratory (CRL) developed a method titled 'Analysis of Diethanolamine, Triethanolamine, n-Methyldiethanolamine, and n-Ethyldiethanolamine in Water by Single Reaction Monitoring Liquid Chromatography/Tandem Mass Spectrometry (LC/MS/MS): EPA Method MS888'. This draft standard operating procedure (SOP) was distributed to multiple EPA laboratories and to Lawrence Livermore National Laboratory, which was tasked to serve as a reference laboratory for EPA's Environmental Reference Laboratory Network (ERLN) and to develop and validate analytical procedures. The primary objective of this study was to validate and verify the analytical procedures described in 'EPA Method MS888' for analysis of themore » listed ethanolamines in aqueous samples. The gathered data from this validation study will be used to: (1) demonstrate analytical method performance; (2) generate quality control acceptance criteria; and (3) revise the SOP to provide a validated method that would be available for use during a homeland security event. The data contained in this report will be compiled, by EPA CRL, with data generated by other EPA Regional laboratories so that performance metrics of 'EPA Method MS888' can be determined.« less

Analysis of Thiodiglycol: Validation of Semi-Volatile Analysis by HPLC-MS/MS by EPA Method MS777

DOE Office of Scientific and Technical Information (OSTI.GOV)

Owens, J; Koester, C

The Environmental Protection Agency's (EPA) Region 5 Chicago Regional Laboratory (CRL) developed a method for the analysis of thiodiglycol, the breakdown product of the sulfur mustard HD, in water by high performance liquid chromatography tandem mass spectrometry (HPLC-MS/MS), titled Method EPA MS777 (hereafter referred to as EPA CRL SOP MS777). This draft standard operating procedure (SOP) was distributed to multiple EPA laboratories and to Lawrence Livermore National Laboratory, which was tasked to serve as a reference laboratory for EPA's Environmental Reference Laboratory Network (ERLN) and to develop and validate analytical procedures. The primary objective of this study was to verifymore » the analytical procedures described in MS777 for analysis of thiodiglycol in aqueous samples. The gathered data from this study will be used to: (1) demonstrate analytical method performance; (2) generate quality control acceptance criteria; and (3) revise the SOP to provide a validated method that would be available for use during a homeland security event. The data contained in this report will be compiled, by EPA CRL, with data generated by other EPA Regional laboratories so that performance metrics of Method EPA MS777 can be determined.« less

One tool - one team: the marriage of test and operations in a low-budget spacecraft development

NASA Astrophysics Data System (ADS)

Finley, Charles J.

2006-05-01

The Air Force Research Laboratory's Space Vehicles Directorate (AFRL/VS) and the Department of Defense Space Test Program (STP) are two organizations that have partnered on more than 85 missions since 1968 to develop, launch, and operate Research and Development, Test and Evaluation space missions. As valuable as these missions have been to the follow-on generation of Operational systems, they are consistently under-funded and forced to execute on excessively ambitious development schedules. Due to these constraints, space mission development teams that serve the RDT&E community are faced with a number of unique technical and programmatic challenges. AFRL and STP have taken various approaches throughout the mission lifecycle to accelerate their development schedules, without sacrificing cost or system reliability. In the areas of test and operations, they currently employ one of two strategies. Historically, they have sought to avoid the added cost and complexity associated with coupled development schedules and segregated the spacecraft development and test effort from the ground operations system development and test effort. However, because these efforts have far more in common than they have differences, they have more recently attempted to pursue parallel I&T and Operations development and readiness efforts. This paper seeks to compare and contrast the "decoupled test and operations" approach, used by such missions as C/NOFS and Coriolis, with the "coupled test and operations" approach, adopted by the XSS-11 and TacSat-2 missions.

Study of the application of advanced technologies to long-range transport aircraft. Volume 2: Research and development requirements

NASA Technical Reports Server (NTRS)

Lange, R. H.; Sturgeon, R. F.; Adams, W. E.; Bradley, E. S.; Cahill, J. F.; Eudaily, R. R.; Hancock, J. P.; Moore, J. W.

1972-01-01

Investigations were conducted to evaluate the relative benefits attainable through the exploitation of advanced technologies and to identify future research and development efforts required to permit the application of selected technologies to transport aircraft entering commercial operation in 1985. Results show that technology advances, particularly in the areas of composite materials, supercritical aerodynamics, and active control systems, will permit the development of long-range, high-payload commercial transports operating at high-subsonic speeds with direct operating costs lower than those of current aircraft. These advanced transports also achieve lower noise levels and lower engine pollutant emissions than current transports. Research and development efforts, including analytical investigations, laboratory test programs, and flight test programs, are required in essentially all technology areas to achieve the potential technology benefits.

Centralization of a regional clinical microbiology service: The Calgary experience

PubMed Central

Church, Deirdre L; Hall, Paula

1999-01-01

Diagnostic laboratory services in Alberta have been dramatically restructured over the past five years. In 1994, Alberta Health embarked on an aggressive laboratory restructuring that cut back approximately 30% of the overall monies previously paid to the laboratory service sector in Calgary. A unique service delivery model consolidated all institutional and community-based diagnostic testing in a company called Calgary Laboratory Services (CLS) in late 1996. CLS was formed by a public/private partnership between the Calgary Regional Health Care Authority (CRHA) and MDS-Kasper Laboratories. By virtue of its customer service base and scope of testing, CLS provides comprehensive regional laboratory services to the entire populace. Regional microbiology services within CLS have been successfully consolidated over the past three years into a centralized high volume laboratory (HVL). Because the HVL is not located in a hospital, rapid response laboratories (RRLs) are operated at each acute care site. Although the initial principle behind the proposed test menus for the RRLs was that only procedures requiring a clinical turnaround time of more than 2 h stay on-site, many other principles had to be used to develop and implement an efficient and clinically relevant RRL model for microbiology. From these guiding principles, a detailed assessment of the needs of each institution and extensive networking with user groups, the functions of the microbiology RRLs were established and a detailed implementation plan drawn up. The experience at CLS with regards to restructuring a regional microbiology service is described herein. A post-hoc analysis provides the pros and cons of directing and operating a regionalized microbiology service. PMID:22346397

The telerobot workstation testbed for the shuttle aft flight deck: A project plan for integrating human factors into system design

NASA Technical Reports Server (NTRS)

Sauerwein, Timothy

1989-01-01

The human factors design process in developing a shuttle orbiter aft flight deck workstation testbed is described. In developing an operator workstation to control various laboratory telerobots, strong elements of human factors engineering and ergonomics are integrated into the design process. The integration of human factors is performed by incorporating user feedback at key stages in the project life-cycle. An operator centered design approach helps insure the system users are working with the system designer in the design and operation of the system. The design methodology is presented along with the results of the design and the solutions regarding human factors design principles.

Low-background gamma-ray spectrometry for the international monitoring system

DOE PAGES

Greenwood, L. R.; Cantaloub, M. G.; Burnett, J. L.; ...

2016-12-28

PNNL has developed two low-background gamma-ray spectrometers in a new shallow underground laboratory, thereby significantly improving its ability to detect low levels of gamma-ray emitting fission or activation products in airborne particulate in samples from the IMS (International Monitoring System). Furthermore, the combination of cosmic veto panels, dry nitrogen gas to reduce radon and low background shielding results in a reduction of the background count rate by about a factor of 100 compared to detectors operating above ground at our laboratory.

University Research Consortium annual review meeting program

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1996-07-01

This brochure presents the program for the first annual review meeting of the University Research Consortium (URC) of the Idaho National Engineering Laboratory (INEL). INEL is a multiprogram laboratory with a distinctive role in applied engineering. It also conducts basic science research and development, and complex facility operations. The URC program consists of a portfolio of research projects funded by INEL and conducted at universities in the United States. In this program, summaries and participant lists for each project are presented as received from the principal investigators.

Idaho National Engineering Laboratory Waste Management Operations Roadmap Document

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bullock, M.

1992-04-01

At the direction of the Department of Energy-Headquarters (DOE-HQ), the DOE Idaho Field Office (DOE-ID) is developing roadmaps for Environmental Restoration and Waste Management (ER&WM) activities at Idaho National Engineering Laboratory (INEL). DOE-ID has convened a select group of contractor personnel from EG&G Idaho, Inc. to assist DOE-ID personnel with the roadmapping project. This document is a report on the initial stages of the first phase of the INEL`s roadmapping efforts.

Equipment Only - Solar Resources Measurements at the University of Texas at Austin, TX: Cooperative Research and Development Final Report, CRADA Number CRD-07-222

DOE Office of Scientific and Technical Information (OSTI.GOV)

Stoffel, T.

Faculty and staff at the University of Texas at Austin collected solar resource measurements at their campus using equipment on loan from the National Renewable Energy Laboratory. The equipment was used to train students on the operation and maintenance of solar radiometers and was returned to NREL's Solar Radiation Research Laboratory upon completion of the CRADA. The resulting data augment the solar resource climatology information required for solar resource characterizations in the U.S. The cooperative agreement was also consistent with NREL's goal of developing an educated workforce to advance renewable energy technologies.

Progress of research on water vapor lidar

NASA Technical Reports Server (NTRS)

Wilkerson, Thomas D.; Singh, U. N.

1989-01-01

Research is summarized on applications of stimulated Raman scattering (SRS) of laser light into near infrared wavelengths suitable for atmospheric monitoring. Issues addressed are conversion efficiency, spectral purity, optimization of operating conditions, and amplification techniques. A Raman cell was developed and built for the laboratory program, and is now available to NASA-Langley, either as a design or as a completed cell for laboratory or flight applications. The Raman cell has been approved for flight in NASA's DC-8 aircraft. The self-seeding SRS technique developed here is suggested as an essential improvement for tunable near-IR DIAL applications at wavelengths of order 1 micrometer or greater.

Facilities and Infrastructure FY 2017 Budget At-A-Glance

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

2016-03-01

The Facilities and Infrastructure Program includes EERE’s capital investments, operations and maintenance, and site-wide support of the National Renewable Energy Laboratory (NREL). It is the nation’s only national laboratory with a primary mission dedicated to the research, development and demonstration (RD&D) of energy efficiency, renewable energy and related technologies. EERE is NREL’s steward, primary client and sponsor of NREL’s designation as a Federally Funded Research and Development Center. The Facilities and Infrastructure (F&I) budget maintains NREL’s research and support infrastructure, ensures availability for EERE’s use, and provides a safe and secure workplace for employees.

Prototype development of a Geostationary Synthetic Thinned Aperture Radiometer, GeoSTAR

NASA Technical Reports Server (NTRS)

Tanner, A. B.; Wilson, W. J.; Kangaslahti, P. P.; Lambrigsten, B. H.; Dinardo, S. J.; Piepmeier, J. R.; Ruf, C. S.; Rogacki, S.; Gross, S. M.; Musko, S.

2004-01-01

Preliminary details of a 2-D synthetic aperture radiometer prototype operating from 50 to 55 GHz will be presented. The laboratory prototype is being developed to demonstrate the technologies and system design needed to do millimeter-wave atmospheric soundings with high spatial resolution from Geostationary orbit. The concept is to deploy a large thinned aperture Y-array on a geostationary satellite, and to use aperture synthesis to obtain images of the Earth without the need for a large mechanically scanned antenna. The laboratory prototype consists of a Y-array of 24 horn antennas, MMIC receivers, and a digital cross-correlation sub-system.

A 2-year study of patient safety competency assessment in 29 clinical laboratories.

PubMed

Reed, Robyn C; Kim, Sara; Farquharson, Kara; Astion, Michael L

2008-06-01

Competency assessment is critical for laboratory operations and is mandated by the Clinical Laboratory Improvement Amendments of 1988. However, no previous reports describe methods for assessing competency in patient safety. We developed and implemented a Web-based tool to assess performance of 875 laboratory staff from 29 laboratories in patient safety. Question categories included workplace culture, categorizing error, prioritization of patient safety interventions, strength of specific interventions, and general patient safety concepts. The mean score was 85.0%, with individual scores ranging from 56% to 100% and scores by category from 81.3% to 88.6%. Of the most difficult questions (<72% correct), 6 were about intervention strength, 3 about categorizing error, 1 about workplace culture, and 1 about prioritization of interventions. Of the 13 questions about intervention strength, 6 (46%) were in the lowest quartile, suggesting that this may be a difficult topic for laboratory technologists. Computer-based competency assessments help laboratories identify topics for continuing education in patient safety.

Performance indicators for quality in surgical and laboratory services at Muhimbili National Hospital (MNH) in Tanzania.

PubMed

Mbembati, Naboth A; Mwangu, Mugwira; Muhondwa, Eustace P Y; Leshabari, Melkizedek M

2008-04-01

Muhimbili National Hospital (MNH), a teaching and national referral hospital, is undergoing major reforms to improve the quality of health care. We performed a retrospective descriptive study using a set of performance indicators for the surgical and laboratory services of MNH in years 2001 and 2002, to help monitor and evaluate the impact of reforms on the quality of health care during and after the reform process. Hospital records were reviewed and information recorded for planned and postponed operations, laboratory equipment, reagents, laboratory tests and quality assurance programmes. In the year 2001 a total of 4332 non-emergency operations were planned, 3313 operations were performed and 1019 (23.5%) operations were postponed. In the year 2002, 4301 non-emergency operations were planned, 3046 were performed and 1255 (29%) were postponed. The most common reasons for operation postponement were "time-barred", interference by emergency operations, no show of patients and inoperable anaesthetic machines. Equipment problems and supply and staff shortages together accounted for one quarter of postponements. In the laboratory, a lack of equipment prevented some tests, but quality assurance was performed for most tests. Current surgical services at MNH are inadequate; operating theatres require modern, functioning equipment and adequate supplies of consumables to provide satisfactory care.

Processing liquid organic wastes at the NNL Preston laboratory

DOE Office of Scientific and Technical Information (OSTI.GOV)

Coppersthwaite, Duncan; Greenwood, Howard; Docrat, Tahera

2013-07-01

Organic compounds of various kinds have been used in the nuclear industry for numerous duties in uranium chemical, metal and ceramic processing plants. In the course of the various operations undertaken, these organic compounds have become contaminated with uranic material, either accidentally or as an inevitable part of the process. Typically, the chemical/physical form and/or concentration of the uranic content of the organics has prevented disposal. In order to address the issue of contaminated liquid organic wastes, the National Nuclear Laboratory (NNL) has developed a suite of treatments designed to recover uranium and to render the waste suitable for disposal.more » The developed processes are operated at industrial scale via the NNL Preston Laboratory Residue Processing Plant. The Oil Waste Leaching (OWL) Process is a fully industrialised process used for the treatment of contaminated oils with approximately 200 tonnes of uranium contaminated oil being treated to date. The process was originally developed for the treatment of contaminated tributyl phosphate and odourless kerosene which had been adsorbed onto sawdust. However, over the years, the OWL process has been refined for a range of oils including 'water emulsifiable' cutting oils, lubricating oils, hydraulic oils/fluids and 'Fomblin' (fully fluorinated) oils. Chemically, the OWL process has proved capable of treating solvents as well as oils but the highly volatile/flammable nature of many solvents has required additional precautions compared with those required for oil treatment. These additional precautions led to the development of the Solvent Treatment Advanced Rig (STAR), an installation operated under an inert atmosphere. STAR is a small 'module' (100 dm{sup 3} volume) which allows the treatment of both water miscible and immiscible solvents. This paper discusses the challenges associated with the treatment of liquid organic wastes and the process developments which have allowed a wide range of materials to be successfully treated. (authors)« less

International Space Station Payload Operations Integration

NASA Technical Reports Server (NTRS)

Fanske, Elizabeth Anne

2011-01-01

The Payload Operations Integrator (POINT) plays an integral part in the Certification of Flight Readiness process for the Mission Operations Laboratory and the Payload Operations Integration Function that supports International Space Station Payload operations. The POINTs operate in support of the POIF Payload Operations Manager to bring together and integrate the Certification of Flight Readiness inputs from various MOL teams through maintaining an open work tracking log. The POINTs create monthly metrics for current and future payloads that the Payload Operations Integration Function supports. With these tools, the POINTs assemble the Certification of Flight Readiness package before a given flight, stating that the Mission Operations Laboratory is prepared to support it. I have prepared metrics for Increment 29/30, maintained the Open Work Tracking Logs for Flights ULF6 (STS-134) and ULF7 (STS-135), and submitted the Mission Operations Laboratory Certification of Flight Readiness package for Flight 44P to the Mission Operations Directorate (MOD/OZ).

Mobile laboratories: An innovative and efficient solution for radiological characterization of sites under or after decommissioning.

PubMed

Goudeau, V; Daniel, B; Dubot, D

2017-04-21

During the operation and the decommissioning of a nuclear site the operator must assure the protection of the workers and the environment. It must furthermore identify and classify the various wastes, while optimizing the associated costs. At all stages of the decommissioning radiological measurements are performed to determine the initial situation, to monitor the demolition and clean-up, and to verify the final situation. Radiochemical analysis is crucial for the radiological evaluation process to optimize the clean-up operations and to the respect limits defined with the authorities. Even though these types of analysis are omnipresent in activities such as the exploitation, the monitoring, and the cleaning up of nuclear plants, some nuclear sites do not have their own radiochemical analysis laboratory. Mobile facilities can overcome this lack when nuclear facilities are dismantled, when contaminated sites are cleaned-up, or in a post-accident situation. The current operations for the characterization of radiological soils of CEA nuclear facilities, lead to a large increase of radiochemical analysis. To manage this high throughput of samples in a timely manner, the CEA has developed a new mobile laboratory for the clean-up of its soils, called SMaRT (Shelter for Monitoring and nucleAR chemisTry). This laboratory is dedicated to the preparation and the radiochemical analysis (alpha, beta, and gamma) of potentially contaminated samples. In this framework, CEA and Eichrom laboratories has signed a partnership agreement to extend the analytical capacities and bring on site optimized and validated methods for different problematic. Gamma-emitting radionuclides can usually be measured in situ as little or no sample preparation is required. Alpha and beta-emitting radionuclides are a different matter. Analytical chemistry laboratory facilities are required. Mobile and transportable laboratories equipped with the necessary tools can provide all that is needed. The main advantage of a mobile laboratory is its portability; the shelter can be placed in the vicinity of nuclear facilities under decommissioning, or of contaminated sites with infrastructures unsuitable for the reception and treatment of radioactive samples. Radiological analysis can then be performed without the disadvantages of radioactive material transport. This paper describes how this solution allows a fast response and control of costs, with a high analytical capacity. Copyright © 2017 Elsevier Ltd. All rights reserved.

Laboratory Information Systems.

PubMed

Henricks, Walter H

2015-06-01

Laboratory information systems (LISs) supply mission-critical capabilities for the vast array of information-processing needs of modern laboratories. LIS architectures include mainframe, client-server, and thin client configurations. The LIS database software manages a laboratory's data. LIS dictionaries are database tables that a laboratory uses to tailor an LIS to the unique needs of that laboratory. Anatomic pathology LIS (APLIS) functions play key roles throughout the pathology workflow, and laboratories rely on LIS management reports to monitor operations. This article describes the structure and functions of APLISs, with emphasis on their roles in laboratory operations and their relevance to pathologists. Copyright © 2015 Elsevier Inc. All rights reserved.

Implementation of a configurable laboratory information management system for use in cellular process development and manufacturing.

PubMed

Russom, Diana; Ahmed, Amira; Gonzalez, Nancy; Alvarnas, Joseph; DiGiusto, David

2012-01-01

Regulatory requirements for the manufacturing of cell products for clinical investigation require a significant level of record-keeping, starting early in process development and continuing through to the execution and requisite follow-up of patients on clinical trials. Central to record-keeping is the management of documentation related to patients, raw materials, processes, assays and facilities. To support these requirements, we evaluated several laboratory information management systems (LIMS), including their cost, flexibility, regulatory compliance, ongoing programming requirements and ability to integrate with laboratory equipment. After selecting a system, we performed a pilot study to develop a user-configurable LIMS for our laboratory in support of our pre-clinical and clinical cell-production activities. We report here on the design and utilization of this system to manage accrual with a healthy blood-donor protocol, as well as manufacturing operations for the production of a master cell bank and several patient-specific stem cell products. The system was used successfully to manage blood donor eligibility, recruiting, appointments, billing and serology, and to provide annual accrual reports. Quality management reporting features of the system were used to capture, report and investigate process and equipment deviations that occurred during the production of a master cell bank and patient products. Overall the system has served to support the compliance requirements of process development and phase I/II clinical trial activities for our laboratory and can be easily modified to meet the needs of similar laboratories.

A survey of Existing V&V, UQ and M&S Data and Knowledge Bases in Support of the Nuclear Energy - Knowledge base for Advanced Modeling and Simulation (NE-KAMS)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hyung Lee; Rich Johnson, Ph.D.; Kimberlyn C. Moussesau

2011-12-01

The Nuclear Energy - Knowledge base for Advanced Modeling and Simulation (NE-KAMS) is being developed at the Idaho National Laboratory in conjunction with Bettis Laboratory, Sandia National Laboratories, Argonne National Laboratory, Oak Ridge National Laboratory, Utah State University and others. The objective of this consortium is to establish a comprehensive knowledge base to provide Verification and Validation (V&V) and Uncertainty Quantification (UQ) and other resources for advanced modeling and simulation (M&S) in nuclear reactor design and analysis. NE-KAMS will become a valuable resource for the nuclear industry, the national laboratories, the U.S. NRC and the public to help ensure themore » safe operation of existing and future nuclear reactors. A survey and evaluation of the state-of-the-art of existing V&V and M&S databases, including the Department of Energy and commercial databases, has been performed to ensure that the NE-KAMS effort will not be duplicating existing resources and capabilities and to assess the scope of the effort required to develop and implement NE-KAMS. The survey and evaluation have indeed highlighted the unique set of value-added functionality and services that NE-KAMS will provide to its users. Additionally, the survey has helped develop a better understanding of the architecture and functionality of these data and knowledge bases that can be used to leverage the development of NE-KAMS.« less

Sandia National Laboratories: National Security Missions: Defense Systems

Science.gov Websites

Technology Partnerships Business, Industry, & Non-Profits Government Universities Center for Development Agreement (CRADA) Strategic Partnership Projects, Non-Federal Entity (SPP/NFE) Agreements New leadership for the national security community by delivering cutting-edge experimental and operational sensor

Crayfish for Research

ERIC Educational Resources Information Center

Poulos, C. Jean

1977-01-01

This article describes how Robert LeBleu's interest in aquatic life developed and that today he owns a large hydroculture operation supplying research crayfish nationwide. Suggested laboratory experiments with crayfish are described, as well as information on additional studies, equipment needs, and tours of the hatchery. (MA)

NASA DC-8 airborne research laboratory

NASA Technical Reports Server (NTRS)

Degreef, Leo H.

1991-01-01

Since the summer of 1987, NASA Ames Research Center has been operating a DC-8 equipped with CFM 56 engines as a flying research laboratory. In this relatively short time, the DC-8, with its tremendous capabilities, has made significant contributions to numerous scientific fields. Capable of staying aloft for over 12 hours, the DC-8 has flown directly over both the North and South Poles, gathering data relating to the ozone hole. Operating from a few thousand feet to over 40,000 feet above sea level the interchangeable payload capability of the DC-8 has made it a versatile scientific tool. The DC-8 also plays a vital role in the development of new satellite-borne sensors as very often those sensors are test-flown on the DC-8 before they are launched into space. The tremendous range and instrument carrying capability make the DC-8 an ideal flying laboratory. A few of the programs the DC-8 has participated in as well as a sampling of the instruments carried are outlined.

Research and Technology 1996: Innovation in Time and Space

NASA Technical Reports Server (NTRS)

1996-01-01

As the NASA Center responsible for assembly, checkout, servicing, launch, recovery, and operational support of Space Transportation System elements and payloads, the John F. Kennedy Space Center is placing increasing emphasis on its advanced technology development program. This program encompasses the efforts of the Engineering Development Directorate laboratories, most of the KSC operations contractors, academia, and selected commercial industries - all working in a team effort within their own areas of expertise. This edition of the Kennedy Space Center Research and Technology 1996 Annual Report covers efforts of all these contributors to the KSC advanced technology development program, as well as our technology transfer activities.

Estimates of emergency operating capacity in US manufacturing and nonmanufacturing industries

DOE Office of Scientific and Technical Information (OSTI.GOV)

Belzer, D.B.; Serot, D.E.; Kellogg, M.A.

1991-03-01

Development of integrated mobilization preparedness policies requires planning estimates of available productive capacity during national emergency conditions. Such estimates must be developed in a manner that allows evaluation of current trends in capacity and the consideration of uncertainties in various data inputs and in engineering assumptions. This study, conducted by Pacific Northwest Laboratory (PNL), developed estimates of emergency operating capacity (EOC) for 446 manufacturing industries at the 4-digit Standard Industrial Classification (SIC) level of aggregation and for 24 key non-manufacturing sectors. This volume presents tabular and graphical results of the historical analysis and projections for each SIC industry. (JF)

Simulation of General Physics laboratory exercise

NASA Astrophysics Data System (ADS)

Aceituno, P.; Hernández-Aceituno, J.; Hernández-Cabrera, A.

2015-01-01

Laboratory exercises are an important part of general Physics teaching, both during the last years of high school and the first year of college education. Due to the need to acquire enough laboratory equipment for all the students, and the widespread access to computers rooms in teaching, we propose the development of computer simulated laboratory exercises. A representative exercise in general Physics is the calculation of the gravity acceleration value, through the free fall motion of a metal ball. Using a model of the real exercise, we have developed an interactive system which allows students to alter the starting height of the ball to obtain different fall times. The simulation was programmed in ActionScript 3, so that it can be freely executed in any operative system; to ensure the accuracy of the calculations, all the input parameters of the simulations were modelled using digital measurement units, and to allow a statistical management of the resulting data, measurement errors are simulated through limited randomization.

Observations of the Performance of the U.S. Laboratory Architecture

NASA Technical Reports Server (NTRS)

Jones, Rod

2002-01-01

The United States Laboratory Module "Destiny" was the product of many architectural, technology, manufacturing, schedule and cost constraints which spanned 15 years. Requirements for the Space Station pressurized elements were developed and baselined in the mid to late '80's. Although the station program went through several design changes the fundamental requirements that drove the architecture did not change. Manufacturing of the U.S. Laboratory began in the early 90's. Final assembly and checkout testing completed in December of 2000. Destiny was launched, mated to the International Space Station and successfully activated on the STS-98 mission in February of 2001. The purpose of this paper is to identify key requirements, which directly or indirectly established the architecture of the U.S. Laboratory. Provide an overview of how that architecture affected the manufacture, assembly, test, and activation of the module on-orbit. And finally, through observations made during the last year of operation, provide considerations in the development of future requirements and mission integration controls for space habitats.

Managing Science: Management for R&D Laboratories

NASA Astrophysics Data System (ADS)

Gelès, Claude; Lindecker, Gilles; Month, Mel; Roche, Christian

1999-10-01

A unique "how-to" manual for the management of scientific laboratories This book presents a complete set of tools for the management of research and development laboratories and projects. With an emphasis on knowledge rather than profit as a measure of output and performance, the authors apply standard management principles and techniques to the needs of high-flux, open-ended, separately funded science and technology enterprises. They also propose the novel idea that failure, and incipient failure, is an important measure of an organization's potential. From the management of complex, round-the-clock, high-tech operations to strategies for long-term planning, Managing Science: Management for R&D Laboratories discusses how to build projects with the proper research and development, obtain and account for funding, and deal with rapidly changing technologies, facilities, and trends. The entire second part of the book is devoted to personnel issues and the impact of workplace behavior on the various functions of a knowledge-based organization. Drawing on four decades of involvement with the management of scientific laboratories, the authors thoroughly illustrate their philosophy with real-world examples from the physics field and provide tables and charts. Managers of scientific laboratories as well as scientists and engineers expecting to move into management will find Managing Science: Management for R&D Laboratories an invaluable practical guide.

Operational Concepts for a Generic Space Exploration Communication Network Architecture

NASA Technical Reports Server (NTRS)

Ivancic, William D.; Vaden, Karl R.; Jones, Robert E.; Roberts, Anthony M.

2015-01-01

This document is one of three. It describes the Operational Concept (OpsCon) for a generic space exploration communication architecture. The purpose of this particular document is to identify communication flows and data types. Two other documents accompany this document, a security policy profile and a communication architecture document. The operational concepts should be read first followed by the security policy profile and then the architecture document. The overall goal is to design a generic space exploration communication network architecture that is affordable, deployable, maintainable, securable, evolvable, reliable, and adaptable. The architecture should also require limited reconfiguration throughout system development and deployment. System deployment includes: subsystem development in a factory setting, system integration in a laboratory setting, launch preparation, launch, and deployment and operation in space.

Scientific Hybrid Realtiy Environments (SHyRE): Bringing Field Work into the Laboratory

NASA Technical Reports Server (NTRS)

Miller, M. J.; Graff, T.; Young, K.; Coan, D.; Whelley, P.; Richardson, J.; Knudson, C.; Bleacher, J.; Garry, W. B.; Delgado, F.;

A helium-3/helium-4 dilution cryocooler for operation in zero gravity

NASA Technical Reports Server (NTRS)

Hendricks, John B.

1988-01-01

This research effort covered the development of He-3/He-4 dilution cryocooler cycles for use in zero gravity. The dilution cryocooler is currently the method of choice for producing temperatures below 0.3 Kelvin in the laboratory. However, the current dilution cryocooler depends on gravity for their operation, so some modification is required for zero gravity operation. In this effort, we have demonstrated, by analysis, that the zero gravity dilution cryocooler is feasible. We have developed a cycle that uses He-3 circulation, and an alternate cycle that uses superfluid He-4 circulation. The key elements of both cycles were demonstrated experimentally. The development of a true 'zero-gravity' dilution cryocooler is now possible, and should be undertaken in a follow-on effort.

Protective clothing for pesticide operators: part II--data analysis of fabric characteristics.

PubMed

Shaw, Anugrah; Schiffelbein, Paul

2016-01-01

Development of objective measurements is an important requirement for establishing performance-based standards for protective clothing used while handling pesticide. This study, the second in a two-part series, reports on the work completed to evaluate the performance of approximately 100 fabrics that are either used or have the potential to be used for garments worn by operators while applying pesticides. Part I, published separately, provides an overview of these issues and describes research undertaken to select a test chemical for use in subsequent studies. The goals of this study were first to develop a comprehensive approach to evaluate the performance of garments currently being used by pesticide operators, and second, to use the laboratory and field data in the development of performance specifications.

Apollo Program Summary Report: Synopsis of the Apollo Program Activities and Technology for Lunar Exploration

NASA Technical Reports Server (NTRS)

1975-01-01

Overall program activities and the technology developed to accomplish lunar exploration are discussed. A summary of the flights conducted over an 11-year period is presented along with specific aspects of the overall program, including lunar science, vehicle development and performance, lunar module development program, spacecraft development testing, flight crew summary, mission operations, biomedical data, spacecraft manufacturing and testing, launch site facilities, equipment, and prelaunch operations, and the lunar receiving laboratory. Appendixes provide data on each of the Apollo missions, mission type designations, spacecraft weights, records achieved by Apollo crewmen, vehicle histories, and a listing of anomalous hardware conditions noted during each flight beginning with Apollo 4.

Law enforcement tools available at the Savannah River Site

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hofstetter, K.J.

A number of nuclear technologies developed and applied at the Savannah River Site in support of nuclear weapons material production and environmental remediation can be applied to problems in law enforcement. Techniques and equipment for high-sensitivity analyses of samples are available to identify and quantify trace elements and establish origins and histories of forensic evidence removed from crime scenes. While some of theses capabilities are available at local crime laboratories, state-of-the-art equipment and breakthroughs in analytical techniques are continually being developed at DOE laboratories. Extensive experience with the handling of radioactive samples at the DOE labs minimizes the chances ofmore » cross-contamination of evidence received from law enforcement. In addition to high-sensitivity analyses, many of the field techniques developed for use in a nuclear facility can assist law enforcement personnel in detecting illicit materials and operations, in retrieving of pertinent evidence and in surveying crime scenes. Some of these tools include chemical sniffers, hand-held detectors, thermal imaging, etc. In addition, mobile laboratories can be deployed to a crime scene to provide field screening of potential evidence. A variety of portable sensors can be deployed on vehicle, aerial, surface or submersible platforms to assist in the location of pertinent evidence or illicit operations. Several specific nuclear technologies available to law enforcement and their potential uses are discussed.« less

Automating the SMAP Ground Data System to Support Lights-Out Operations

NASA Technical Reports Server (NTRS)

Sanders, Antonio

2014-01-01

The Soil Moisture Active Passive (SMAP) Mission is a first tier mission in NASA's Earth Science Decadal Survey. SMAP will provide a global mapping of soil moisture and its freeze/thaw states. This mapping will be used to enhance the understanding of processes that link the terrestrial water, energy, and carbon cycles, and to enhance weather and forecast capabilities. NASA's Jet Propulsion Laboratory has been selected as the lead center for the development and operation of SMAP. The Jet Propulsion Laboratory (JPL) has an extensive history of successful deep space exploration. JPL missions have typically been large scale Class A missions with significant budget and staffing. SMAP represents a new area of JPL focus towards low cost Earth science missions. Success in this new area requires changes to the way that JPL has traditionally provided the Mission Operations System (MOS)/Ground Data System (GDS) functions. The operation of SMAP requires more routine operations activities and support for higher data rates and data volumes than have been achieved in the past. These activities must be addressed by a reduced operations team and support staff. To meet this challenge, the SMAP ground data system provides automation that will perform unattended operations, including automated commanding of the SMAP spacecraft.

[Construction and operation status of management system of laboratories of schistosomiasis control institutions in Hubei Province].

PubMed

Zhao-Hui, Zheng; Jun, Qin; Li, Chen; Hong, Zhu; Li, Tang; Zu-Wu, Tu; Ming-Xing, Zeng; Qian, Sun; Shun-Xiang, Cai

2016-10-09

To analyze the construction and operation status of management system of laboratories of schistosomiasis control institutions in Hubei Province, so as to provide the reference for the standardized detection and management of schistosomiasis laboratories. According to the laboratory standard of schistosomiasis at provincial, municipal and county levels, the management system construction and operation status of 60 schistosomiasis control institutions was assessed by the acceptance examination method from 2013 to 2015. The management system was already occupied over all the laboratories of schistosomiasis control institutions and was officially running. There were 588 non-conformities and the inconsistency rate was 19.60%. The non-conformity rate of the management system of laboratory quality control was 38.10% (224 cases) and the non-conformity rate of requirements of instrument and equipment was 23.81% (140 cases). The management system has played an important role in the standardized management of schistosomiasis laboratories.

Mars Science Laboratory Rover Mobility Bushing Development

NASA Technical Reports Server (NTRS)

Riggs, Benjamin

2008-01-01

NASA s Mars Science Laboratory (MSL) Project will send a six-wheeled rover to Mars in 2009. The rover will carry a scientific payload designed to search for organic molecules on the Martian surface during its primary mission. This paper describes the development and testing of a bonded film lubricated bushing system to be used in the mobility system of the rover. The MSL Rover Mobility System contains several pivots that are tightly constrained with respect to mass and volume. These pivots are also exposed to relatively low temperatures (-135 C) during operation. The combination of these constraints led the mobility team to consider the use of solid film lubricated metallic bushings and dry running polymeric bushings in several flight pivot applications. A test program was developed to mitigate the risk associated with using these materials in critical pivots on the MSL vehicle. The program was designed to characterize bushing friction and wear performance over the expected operational temperature range (-135 C to +70 C). Seven different bushing material / lubricant combinations were evaluated to aid in the selection of the final flight pivot bushing material / lubricant combination.

Experimental Performance of the NRL 8-Beam, 4-Cavity Multiple-Beam Klystron

NASA Astrophysics Data System (ADS)

Abe, D. K.; Pershing, D. E.; Nguyen, K. T.; Wood, F. N.; Myers, R. E.; Eisen, E. L.; Cusick, M.; Levush, B.

2006-01-01

Multiple-beam amplifiers (MBAs) represent a device technology with the potential to produce high-power, efficient amplifiers with relatively wide bandwidths that are compact, low-weight, low-noise, and operate at reduced voltages relative to comparable single-beam devices. To better understand the device physics and technical issues involved in the design, fabrication, and operation of these devices, the U.S. Naval Research Laboratory (NRL) has an on-going program to develop high peak power (> 600 kW) multiple-beam klystrons (MBKs) operating in S-band (˜3.3 GHz).

The workload book: Assessment of operator workload to engineering systems

NASA Technical Reports Server (NTRS)

Gopher, D.

1983-01-01

The structure and initial work performed toward the creation of a handbook for workload analysis directed at the operational community of engineers and human factors psychologists are described. The goal, when complete, will be to make accessible to such individuals the results of theoretically-based research that are of practical interest and utility in the analysis and prediction of operator workload in advanced and existing systems. In addition, the results of laboratory study focused on the development of a subjective rating technique for workload that is based on psychophysical scaling techniques are described.

New Earth Observation Capabilities For The Commercial Sector

NASA Technical Reports Server (NTRS)

Stefanov, William L.

2017-01-01

Earth observation data collected from orbital remote sensing systems are becoming increasingly critical to the short- and long-term operations of many commercial industries including agriculture, energy exploration, environmental management, transportation, and urban planning and operations. In this panel, I will present an overview of current and planned NASA remote sensing systems for Earth observation with relevance to commercial and industrial applications. Special emphasis will be given to the International Space Station (ISS) as a platform for both commercial technology demonstration/development and operational data collection through the ISS National Laboratory.

Development of a safe ground to space laser propagation system for the optical communications telescope laboratory

NASA Technical Reports Server (NTRS)

Wu, Janet P.

2003-01-01

Furthering pursuits in high bandwidth communications to future NASA deep space and neat-Earth probes, the Jet Propulsion Laboratory (JPL) is building the Optical communications Telescope Laboratory (OCTL) atop Table Mountain in Southern California. This R&D optical antenna will be used to develop optical communication strategies for future optical ground stations. Initial experiments to be conducted include propagating high-powered, Q-switched laser beams to retro-reflecting satellites. Yet laser beam propagation from the ground to space is under the cognizance of various government agencies, namely: the Occupational Safety and Health Administration (ISHA) that is responsible for protecting workforce personnel; the Federal Aviation Administration (FAA) responsible for protecting pilots and aircraft; and the Laser Clearinghouse of Space Command responsible for protecting space assets. To ensure that laser beam propagation from the OCTL and future autonomously operated ground stations comply with the guidelines of these organizations, JPL is developing a multi-tiered safety system that will meet the coordination, monitoring, and reporting functions required by the agencies. At Tier 0, laser operators will meet OSHA safety standards for protection and access to the high power lasers area will be restricted and interlocked. Tier 1, the area defined from the telescope dome out to a range of 3.4-km, will utilize long wave infrared camera sensors to alert operators of at risk aircraft in the FAA controlled airspace. Tier 2, defined to extend from 3.4-km out to the aircraft service ceiling in FAA airspace, will detect at risk aircraft by radar. Lastly, beam propagation into space, defined as Tier 3, will require coordination with the Laser Clearinghouse. A detailed description of the four tiers is presented along with the design of the integrated monitoring and beam transmission control system.

Development of a computed tomography-based scoring system for necrotizing soft-tissue infections.

PubMed

McGillicuddy, Edward A; Lischuk, Andrew W; Schuster, Kevin M; Kaplan, Lewis J; Maung, Adrian; Lui, Felix Y; Bokhari, S A Jamal; Davis, Kimberly A

2011-04-01

Necrotizing soft-tissue infections (NSTIs) are associated with significant morbidity and mortality, but a definitive nonsurgical diagnostic test remains elusive. Despite the widespread use of computed tomography (CT) as a diagnostic adjunct, there is little data that definitively correlate CT findings with the presence of NSTI. Our goal was the development of a CT-based scoring system to discriminate non-NSTI from NSTI. Patients older than 17 years undergoing CT for evaluation of soft-tissue infection at a tertiary care medical center over a 10-year period (2000-2009) were included. Abstracted data included comorbidities and social history, physical examination, laboratory findings, and operative and pathologic findings. NSTI was defined as soft-tissue necrosis in the dictated operative note or the accompanying pathology report. CT scans were reviewed by a radiologist blinded to clinical and laboratory data. A scoring system was developed and the area under the receiver operating characteristic curve was calculated. During the study period, 305 patients underwent CT scanning (57% men; mean age, 47.4 years). Forty-four patients (14.4%) evaluated had an NSTI. A scoring system was retrospectively developed (table). A score >6 points was 86.3% sensitive and 91.5% specific for the diagnosis of NSTI (positive predictive value, 63.3%; negative predictive value, 85.5%). The area under the receiver operating characteristic curve was 0.928 (95% confidence interval, 0.893-0.964). The mean score of the non-NSTI group was 2.74. We have developed a CT scoring system that is both sensitive and specific for the diagnosis of NSTIs. This system may allow clinicians to more accurately diagnose NSTIs. Prospective validation of this scoring system is planned.

The Tanzania experience: clinical laboratory testing harmonization and equipment standardization at different levels of a tiered health laboratory system.

PubMed

Massambu, Charles; Mwangi, Christina

2009-06-01

The rapid scale-up of the care and treatment programs in Tanzania during the preceding 4 years has greatly increased the demand for quality laboratory services for diagnosis of HIV and monitoring patients during antiretroviral therapy. Laboratory services were not in a position to cope with this demand owing to poor infrastructure, lack of human resources, erratic and/or lack of reagent supply and commodities, and slow manual technologies. With the limited human resources in the laboratory and the need for scaling up the care and treatment program, it became necessary to install automated equipment and train personnel for the increased volume of testing and new tests across all laboratory levels. With the numerous partners procuring equipment, the possibility of a multitude of equipment platforms with attendant challenges for procurement of reagents, maintenance of equipment, and quality assurance arose. Tanzania, therefore, had to harmonize laboratory tests and standardize laboratory equipment at different levels of the laboratory network. The process of harmonization of tests and standardization of equipment included assessment of laboratories, review of guidelines, development of a national laboratory operational plan, and stakeholder advocacy. This document outlines this process.

Radio frequency multicusp ion source development (invited)

NASA Astrophysics Data System (ADS)

Leung, K. N.

1996-03-01

The radio-frequency (rf) driven multicusp source was originally developed for use in the Superconducting Super Collider injector. It has been demonstrated that the source can meet the H- beam current and emittance requirements for this application. By employing a porcelain-coated antenna, a clean plasma discharge with very long-life operation can be achieved. Today, the rf source is used to generate both positive and negative hydrogen ion beams and has been tested in various particle accelerator laboratories throughout the world. Applications of this ion source have been extended to other fields such as ion beam lithography, oil-well logging, ion implantation, accelerator mass spectrometry and medical therapy machines. This paper summarizes the latest rf ion source technology and development at the Lawrence Berkeley National Laboratory.

Changes and challenges in the Software Engineering Laboratory

NASA Technical Reports Server (NTRS)

Pajerski, Rose

1994-01-01

Since 1976, the Software Engineering Laboratory (SEL) has been dedicated to understanding and improving the way in which one NASA organization, the Flight Dynamics Division (FDD), develops, maintains, and manages complex flight dynamics systems. The SEL is composed of three member organizations: NASA/GSFC, the University of Maryland, and Computer Sciences Corporation. During the past 18 years, the SEL's overall goal has remained the same: to improve the FDD's software products and processes in a measured manner. This requires that each development and maintenance effort be viewed, in part, as a SEL experiment which examines a specific technology or builds a model of interest for use on subsequent efforts. The SEL has undertaken many technology studies while developing operational support systems for numerous NASA spacecraft missions.

Development and performance of a laser heterodyne spectrometer using tunable semiconductor lasers as local oscillators

NASA Technical Reports Server (NTRS)

Glenar, D.; Kostiuk, T.; Jennings, D. E.; Mumma, M. J.

1980-01-01

A diode laser based IR heterodyne spectrometer for laboratory and field use was developed for high efficiency operation between 7.5 and 8.5 microns. The local oscillator is a PbSSe tunable diode laser kept continuously at operating temperatures of 12-60 K using a closed cycle cooler. The laser output frequency is controlled and stabilized using a high precision diode current supply, constant temperature controller, and a shock isolator mounted between the refrigerator cold tip and the diode mount. Single laser modes are selected by a grating placed in the local oscillator beam. The system employs reflecting optics throughout to minimize losses from internal reflection and absorption, and to eliminate chromatic effects. Spectral analysis of the diode laser output between 0 and 1 GHz reveals excess noise at many diode current settings, which limits the infrared spectral regions over which useful heterodyne operation can be achieved. System performance has been studied by making heterodyne measurements of etalon fringes and several Freon 13 (CF3Cl) absorption lines against a laboratory blackbody source. Preliminary field tests have also been performed using the Sun as a source.

Biobanking of different body fluids within the frame of IVF-a standard operating procedure to improve reproductive biology research.

PubMed

Schenk, Michael; Huppertz, Berthold; Obermayer-Pietsch, Barbara; Kastelic, Darja; Hörmann-Kröpfl, Martina; Weiss, Gregor

2017-02-01

The aim of the present study was to develop a standard operating procedure (SOP) for the collection, transport, and storage of human cumulus cells, follicular fluid, blood serum, seminal plasma, embryo culture supernatant, and embryo culture supernatant control obtained within the IVF process under approved protocols and written informed consent from participating patients. The SOP was developed at the Kinderwunsch Institut Schenk, Dobl, Austria, together with Biobank Graz of the Medical University of Graz, Austria. The SOP provides comprehensive details of laboratory procedures and sampling of the different fluids within the IVF process. Furthermore, information on sample coding, references of involved laboratory techniques (e.g., oocyte retrieval with a Steiner-TAN needle), ethical approvals, and biobanking procedures are presented. The result of the present study is a standard operating procedure. The SOP ensures a professional way for collection and scientific use of IVF samples by the Kinderwunsch Institut Schenk, Dobl, Austria, and Biobank Graz of the Medical University of Graz, Austria. It can be used as a template for other institutions to unify specimen collection procedures in the field of reproductive health research.

Development of a Long-Range Underwater Vehicle

DTIC Science & Technology

2014-09-30

lithium- seawater batteries . Specific objectives are (1) to test in the laboratory and ocean new lithium- seawater batteries developed and manufactured...by the PolyPlus Battery Company, (2) to discover how to mount and operate these cells to maximize their mass transfer with the ambient seawater and to...respectively. The achievable energy density for batteries is much less. PolyPlus Battery Company has developed a lithium- seawater battery (http

Accurate quantum Z rotations with less magic

NASA Astrophysics Data System (ADS)

Landahl, Andrew; Cesare, Chris

2013-03-01

We present quantum protocols for executing arbitrarily accurate π /2k rotations of a qubit about its Z axis. Unlike reduced instruction set computing (RISC) protocols which use a two-step process of synthesizing high-fidelity ``magic'' states from which T = Z (π / 4) gates can be teleported and then compiling a sequence of adaptive stabilizer operations and T gates to approximate Z (π /2k) , our complex instruction set computing (CISC) protocol distills magic states for the Z (π /2k) gates directly. Replacing this two-step process with a single step results in substantial reductions in the number of gates needed. The key to our construction is a family of shortened quantum Reed-Muller codes of length 2 k + 2 - 1 , whose distillation threshold shrinks with k but is greater than 0.85% for k <= 6 . AJL and CC were supported in part by the Laboratory Directed Research and Development program at Sandia National Laboratories. Sandia National Laboratories is a multi-program laboratory managed and operated by Sandia Corporation, a wholly owned subsidiary of Lockheed Martin Corporation, for the U.S. Department of Energy's National Nuclear Security Administration under contract DE-AC04-94AL85000.

Ion mobility spectrometry evaluation of cocaine occupational exposure in forensic laboratories.

PubMed

Armenta, Sergio; de la Guardia, Miguel; Alcalà, Manel; Blanco, Marcelo; Perez-Alfonso, Clara; Galipienso, Nieves

2014-12-01

An approach, based on ion mobility spectrometry (IMS) has been developed for the control of cocaine in air of the breathing zone of operators, in laboratory surfaces and in nasal mucus of employees to evaluate cocaine exposure in a forensic laboratory. The analytical methodology has been validated in terms of accuracy, precision and limits of detection and results obtained were statistically comparable with those obtained by liquid chromatography. Cocaine concentration in laboratory air increases from 100 ± 35 ng m(-3) of a normal day to 10,000 ng m(-3) during the manipulation of cocaine seizures. The occupational exposure limit (OEL) for cocaine has not been established which difficult the evaluation of the health effects of continuous exposition to very small doses of cocaine. Cocaine was also found in almost all the analyzed sample surfaces and also was found in nasal mucus of the police officers that were present during the manipulation of cocaine seizures without using a face mask. In summary, cocaine concentrations could present a health hazard to the employees and therefore warrants remediation and some modifications of the manipulation operations have been proposed. Copyright © 2014 Elsevier B.V. All rights reserved.

NASA's DC-8 flying laboratory takes off from Juan Santamaria International Airport in San Jose, Costa Rica, on NASA's AirSAR 2004 campaign

NASA Image and Video Library

2004-03-06

NASA's DC-8 flying laboratory takes off from Juan Santamaria International Airport in San Jose, Costa Rica, on NASA's AirSAR 2004 campaign. AirSAR 2004 Mesoamerica is a three-week expedition by an international team of scientists that uses an all-weather imaging tool, called the Airborne Synthetic Aperture Radar (AirSAR) which is located onboard NASA's DC-8 airborne laboratory. Scientists from many parts of the world including NASA's Jet Propulsion Laboratory are combining ground research done in several areas in Central America with NASA's AirSAR technology to improve and expand on the quality of research they are able to conduct. The radar, developed by NASA's Jet Propulsion Laboratory, can penetrate clouds and also collect data at night. Its high-resolution sensors operate at multiple wavelengths and modes, allowing AirSAR to see beneath treetops, through thin sand, and dry snow pack. AirSAR's 2004 campaign is a collaboration of many U.S. and Central American institutions and scientists, including NASA; the National Science Foundation; the Smithsonian Institution; National Geographic; Conservation International; the Organization of Tropical Studies; the Central American Commission for Environment and Development; and the Inter-American Development Bank.

7 CFR 58.442 - Laboratory and quality control tests.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Laboratory and quality control tests. 58.442 Section... Service 1 Operations and Operating Procedures § 58.442 Laboratory and quality control tests. (a) Chemical... Methods or by other methods giving equivalent results. (b) Weight or volume control. Representative...

7 CFR 58.442 - Laboratory and quality control tests.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 3 2011-01-01 2011-01-01 false Laboratory and quality control tests. 58.442 Section... Service 1 Operations and Operating Procedures § 58.442 Laboratory and quality control tests. (a) Chemical... Methods or by other methods giving equivalent results. (b) Weight or volume control. Representative...

Microbial ecology laboratory procedures manual NASA/MSFC

NASA Technical Reports Server (NTRS)

Huff, Timothy L.

1990-01-01

An essential part of the efficient operation of any microbiology laboratory involved in sample analysis is a standard procedures manual. The purpose of this manual is to provide concise and well defined instructions on routine technical procedures involving sample analysis and methods for monitoring and maintaining quality control within the laboratory. Of equal importance is the safe operation of the laboratory. This manual outlines detailed procedures to be followed in the microbial ecology laboratory to assure safety, analytical control, and validity of results.

Computational Simulation of a Water-Cooled Heat Pump

NASA Technical Reports Server (NTRS)

Bozarth, Duane

2008-01-01

A Fortran-language computer program for simulating the operation of a water-cooled vapor-compression heat pump in any orientation with respect to gravity has been developed by modifying a prior general-purpose heat-pump design code used at Oak Ridge National Laboratory (ORNL).

Development of a portable passive-acoustic bedload monitoring system

USDA-ARS?s Scientific Manuscript database

A hydrophone-based passive acoustic bedload-monitoring system was designed, tested and deployed by researchers at the University of Mississippi and the National Sedimentation Laboratory in Oxford, MS. The hydrophone system was designed to be easily deployed and operated by non-experts. In addition, ...

EFFICIENCY OPTIMIZATIN CONTROL OF AC INDUCTION MOTORS: INITIAL LABORATORY RESULTS

EPA Science Inventory

The report discusses the development of a fuzzy logic, energy-optimizing controller to improve the efficiency of motor/drive combinations that operate at varying loads and speeds. This energy optimizer is complemented by a sensorless speed controller that maintains motor shaft re...

10 CFR 26.157 - Procedures.

Code of Federal Regulations, 2010 CFR

2010-01-01

... of standard operating procedures for each assay performed for licensees and other entities for drug... 10 Energy 1 2010-01-01 2010-01-01 false Procedures. 26.157 Section 26.157 Energy NUCLEAR... Services § 26.157 Procedures. (a) HHS-certified laboratories shall develop, implement, and maintain clear...

10 CFR 26.157 - Procedures.

Code of Federal Regulations, 2013 CFR

2013-01-01

... of standard operating procedures for each assay performed for licensees and other entities for drug... 10 Energy 1 2013-01-01 2013-01-01 false Procedures. 26.157 Section 26.157 Energy NUCLEAR... Services § 26.157 Procedures. (a) HHS-certified laboratories shall develop, implement, and maintain clear...

10 CFR 26.157 - Procedures.

Code of Federal Regulations, 2011 CFR

2011-01-01

... of standard operating procedures for each assay performed for licensees and other entities for drug... 10 Energy 1 2011-01-01 2011-01-01 false Procedures. 26.157 Section 26.157 Energy NUCLEAR... Services § 26.157 Procedures. (a) HHS-certified laboratories shall develop, implement, and maintain clear...

10 CFR 26.157 - Procedures.

Code of Federal Regulations, 2014 CFR

2014-01-01

... of standard operating procedures for each assay performed for licensees and other entities for drug... 10 Energy 1 2014-01-01 2014-01-01 false Procedures. 26.157 Section 26.157 Energy NUCLEAR... Services § 26.157 Procedures. (a) HHS-certified laboratories shall develop, implement, and maintain clear...

10 CFR 26.157 - Procedures.

Code of Federal Regulations, 2012 CFR

2012-01-01

... of standard operating procedures for each assay performed for licensees and other entities for drug... 10 Energy 1 2012-01-01 2012-01-01 false Procedures. 26.157 Section 26.157 Energy NUCLEAR... Services § 26.157 Procedures. (a) HHS-certified laboratories shall develop, implement, and maintain clear...

NREL Technical Reports Guide the Way to 50% Energy Savings in Hospitals, Office Buildings (Fact Sheet)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

2011-02-01

Researchers at the National Renewable Energy Laboratory (NREL) have developed two technical reports that provide recommendations to help designers and operators of large office buildings and hospitals achieve at least a 50% energy savings using existing technology.

Differential Effects of Activity-Oriented vs. Textbook-Oriented Mathematics Instruction for Elementary School Children with Learning and Behavior Problems. Monograph No. 4.

ERIC Educational Resources Information Center

Dunlap, William; And Others

Compared were the effects of two experimental arithmetic treatments, called Laboratory and Textbook, upon achievement and attitude development of fourth grade children. Prior to the study, the experimenter employed task analysis procedures to develop hierarchies of skills for the four operations on whole numbers. During the instructional phase of…

System reliability analysis through corona testing

NASA Technical Reports Server (NTRS)

Lalli, V. R.; Mueller, L. A.; Koutnik, E. A.

1975-01-01

In the Reliability and Quality Engineering Test Laboratory at the NASA Lewis Research Center a nondestructive, corona-vacuum test facility for testing power system components was developed using commercially available hardware. The test facility was developed to simulate operating temperature and vacuum while monitoring corona discharges with residual gases. This facility is being used to test various high voltage power system components.

Rovers Pave the Way for Hospital Robots

NASA Technical Reports Server (NTRS)

2013-01-01

The Jet Propulsion Laboratory provided funding for the Massachusetts Institute of Technology to develop capabilities for robotics like Rocky 7. After developing the operating system, Daniel Theobald started working at Cambridge, Massachusetts-based Vecna Technologies. Today, Vecna's QC Bot incorporates systems based on the NASA work and is being used to ease logistics at hospitals. The technology has contributed to 20 new jobs.

How to evaluate a potential merger or acquisition.

PubMed

Horowitz, Richard E; Provizer, Harold; Barry, Michael J

2013-12-01

Economic imperatives in health care financing are compelling a variety of mergers, acquisitions, integrations, and other forms of amalgamation. As hospitals merge, their pathology practices are merging. Physicians are forming clinically integrated groups, both with and without hospitals. Universities, commercial laboratories, and even insurance companies are acquiring laboratories and pathology practices. There are few standards or guidelines to help the practicing pathologist respond to such new undertakings. In the present study, we present a "how-to" guide or template to assist pathologists in evaluating proposals to amalgamate and in managing the alliance. The procedure begins with an articulation of the cons and pros, followed by a series of assessments of the cultures, the market, the organization, and operations, as well as a legal and financial assessment and human resources appraisal of each of the entities. We then outline the method for developing an organizational and operational model for the new merged entity and for performing the feasibility analysis, making a final decision, drafting a contract, and developing the business plan for the new venture.

An Automated Thermocouple Calibration System

NASA Technical Reports Server (NTRS)

Bethea, Mark D.; Rosenthal, Bruce N.

1992-01-01

An Automated Thermocouple Calibration System (ATCS) was developed for the unattended calibration of type K thermocouples. This system operates from room temperature to 650 C and has been used for calibration of thermocouples in an eight-zone furnace system which may employ as many as 60 thermocouples simultaneously. It is highly efficient, allowing for the calibration of large numbers of thermocouples in significantly less time than required for manual calibrations. The system consists of a personal computer, a data acquisition/control unit, and a laboratory calibration furnace. The calibration furnace is a microprocessor-controlled multipurpose temperature calibrator with an accuracy of +/- 0.7 C. The accuracy of the calibration furnace is traceable to the National Institute of Standards and Technology (NIST). The computer software is menu-based to give the user flexibility and ease of use. The user needs no programming experience to operate the systems. This system was specifically developed for use in the Microgravity Materials Science Laboratory (MMSL) at the NASA LeRC.

Applications of ISES for meteorology

NASA Technical Reports Server (NTRS)

Try, Paul D.

1990-01-01

The results are summarized from an initial assessment of the potential real-time meteorological requirements for the data from Eos systems. Eos research scientists associated with facility instruments, investigator instruments, and interdisciplinary groups with data related to meteorological support were contacted, along with those from the normal operational user and technique development groups. Two types of activities indicated the greatest need for real-time Eos data: technology transfer groups (e.g., NOAA's Forecasting System Laboratory and the DOD development laboratories), and field testing groups with airborne operations. A special concern was expressed by several non-U.S. participants who desire a direct downlink to be sure of rapid receipt of the data for their area of interest. Several potential experiments or demonstrations are recommended for ISES which include support for hurricane/typhoon forecasting, space shuttle reentry, severe weather forecasting (using microphysical cloud classification techniques), field testing, and quick reaction of instrumented aircraft to measure such events as polar stratospheric clouds and volcanic eruptions.

Design Construction and Operation of a Supercritical Carbon Dioxide (sCO 2) Loop for Investigation of Dry Cooling and Natural Circulation Potential for Use in Advanced Small Modular Reactors Utilizing sCO 2 Power Conversion Cycles.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Middleton, Bobby D.; Rodriguez, Salvador B.; Carlson, Matthew David

This report outlines the work completed for a Laboratory Directed Research and Development project at Sandia National Laboratories from October 2012 through September 2015. An experimental supercritical carbon dioxide (sCO 2 ) loop was designed, built, and o perated. The experimental work demonstrated that sCO 2 can be uti lized as the working fluid in an air - cooled, natural circulation configuration to transfer heat from a source to the ultimate heat sink, which is the surrounding ambient environment in most ca ses. The loop was also operated in an induction - heated, water - cooled configuration that allows formore » measurements of physical parameters that are difficult to isolate in the air - cooled configuration. Analysis included the development of two computational flu id dynamics models. Future work is anticipated to answer questions that were not covered in this project.« less

A curriculum for real-time computer and control systems engineering

NASA Technical Reports Server (NTRS)

Halang, Wolfgang A.

1990-01-01

An outline of a syllabus for the education of real-time-systems engineers is given. This comprises the treatment of basic concepts, real-time software engineering, and programming in high-level real-time languages, real-time operating systems with special emphasis on such topics as task scheduling, hardware architectures, and especially distributed automation structures, process interfacing, system reliability and fault-tolerance, and integrated project development support systems. Accompanying course material and laboratory work are outlined, and suggestions for establishing a laboratory with advanced, but low-cost, hardware and software are provided. How the curriculum can be extended into a second semester is discussed, and areas for possible graduate research are listed. The suitable selection of a high-level real-time language and supporting operating system for teaching purposes is considered.

Processing of Mars Exploration Rover Imagery for Science and Operations Planning

NASA Technical Reports Server (NTRS)

Alexander, Douglass A.; Deen, Robert G.; Andres, Paul M.; Zamani, Payam; Mortensen, Helen B.; Chen, Amy C.; Cayanan, Michael K.; Hall, Jeffrey R.; Klochko, Vadim S.; Pariser, Oleg;

Laboratory medicine in France. A jeopardized situation.

PubMed

Valdiguié, P M; de Graeve, J S; Guerre, J P

1997-11-06

The expenses for health care in France have risen considerably during the present decade, ranking third after USA and Canada in the Western world. In spite of the very low cost of laboratory medicine (2.4% of the total expenditure in 1995), clinical laboratories have undergone a severe squeeze, due to two limiting factors; a decrease in the ordering of laboratory tests from private physicians and a reduction in the total expenses for laboratory services from the Social Security. Consequently, there has been unemployment of technical and secretarial staff and severe restriction in investment for buying new equipment. However, hospital laboratories will manage to assume their challenge in developing robotics, automation, molecular pathology techniques and expert systems. Private laboratories, in spite of their efforts to follow the technological advances in automation, will survive thanks to consolidation of regional networks that operate in a cooperative rather than competitive mode. Therefore, the challenge will be not in the adaptation of clinical laboratories, but in the limitation of overspending at the national level and in modification of the behaviour of irresponsible citizens accustomed to spending freely on health care services.

[Role of medium-sized independent laboratories in control of healthcare-associated infection].

PubMed

Anzai, Eiko; Fukui, Toru

2009-05-01

In 2006, the Ministry of Health and Welfare revised the regulations regarding the Medical Service Law. The amendments stipulate that all healthcare institutions are required to implement infection control programs. However, small hospitals and clinics have no clinical microbiology laboratories, whereas medium-sized hospitals have few medical technologists and the outsourcing of microbiology tests to independent laboratories is common. The decreasing number of laboratories and recent outsourcing tendency reflect the increasing commercialization, and, with it, the escalating number of commercially operating chains. Each independent laboratory is responsible for supporting activities related to the surveillance, control, and prevention of healthcare-associated infections in the associated small and medium-sized hospitals. The people responsible for infection control in these hospitals usually do not have a background in microbiology. The evaluation of communication between independent laboratory staff and hospital personnel, and rapid turnaround time of microbiology laboratory test reports are important elements ensuring the quality of independent laboratory work. With the pressures of financial constraints in the Japanese medical insurance system, the development of a cost-effective and practical protocol for quality assurance is a real dilemma.

The future of hospital laboratories. Position statement from the Royal Belgian Society of Clinical Chemistry (RBSCC).

PubMed

Langlois, Michel R; Wallemacq, Pierre

2009-01-01

To face the economic pressures arising from the current socio-economic conjuncture, hospital laboratories are endangered by an increasing trend towards the outsourcing of clinical laboratory tests to external (mega-) laboratories. This should allow hospitals to meet their economic requirements, but with an increased risk of loss of medical quality and, mid- to long-term, loss of cost effectiveness of healthcare at the national level. To anticipate current developments (economical and technological) that inevitably will affect the future of laboratory medicine, hospital laboratories should be proactive and enhance efficiency, reduce costs by consolidation, integrate into regional networks, and form alliances or partnerships. To create additional value, the core competency of laboratory professionals must be refocused to provide medical knowledge services (consultative support to clinicians) related to in vitro diagnostic testing. To integrate cost-efficiency with medical quality, implementation of a matricial organization - operational vs. biomedical level - could be an interesting approach. This integrated structure should create total quality of laboratory testing, managing the entire medical diagnostic cycle from the pre-preanalytical to post-postanalytical phase.

Using SFOC to fly the Magellan Venus mapping mission

NASA Technical Reports Server (NTRS)

Bucher, Allen W.; Leonard, Robert E., Jr.; Short, Owen G.

1993-01-01

Traditionally, spacecraft flight operations at the Jet Propulsion Laboratory (JPL) have been performed by teams of spacecraft experts utilizing ground software designed specifically for the current mission. The Jet Propulsion Laboratory set out to reduce the cost of spacecraft mission operations by designing ground data processing software that could be used by multiple spacecraft missions, either sequentially or concurrently. The Space Flight Operations Center (SFOC) System was developed to provide the ground data system capabilities needed to monitor several spacecraft simultaneously and provide enough flexibility to meet the specific needs of individual projects. The Magellan Spacecraft Team utilizes the SFOC hardware and software designed for engineering telemetry analysis, both real-time and non-real-time. The flexibility of the SFOC System has allowed the spacecraft team to integrate their own tools with SFOC tools to perform the tasks required to operate a spacecraft mission. This paper describes how the Magellan Spacecraft Team is utilizing the SFOC System in conjunction with their own software tools to perform the required tasks of spacecraft event monitoring as well as engineering data analysis and trending.

Improving ISR Radar Utilization (How I quit blaming the user and made the radar easier to use).

DOE Office of Scientific and Technical Information (OSTI.GOV)

Doerry, Armin Walter

In modern multi - sensor multi - mode Intelligence, Surveillance, and Reconnaissance ( ISR ) platforms, the plethora of options available to a sensor/payload operator are quite large, leading to an over - worked operator often down - selecting to favorite sensors an d modes. For example, Full Motion Video (FMV) is justifiably a favorite sensor at the expense of radar modes, even if radar modes can offer unique and advantageous information. The challenge is then to increase the utilization of the radar modes in a man ner attractive to the sensor/payload operator. We propose that this is best accomplishedmore » by combining sensor modes and displays into 'super - modes'. - 4 - Acknowledgements This report is the result of a n unfunded research and development activity . Sandia Natio nal Laboratories is a multi - program laboratory managed and operated by Sandia Corporation, a wholly owned subsidiary of Lockheed Martin Corporation, for the U.S. Department of Energy's National Nuclear Security Administration under contract DE - AC04 - 94AL850 00.« less

A Prototype Lisp-Based Soft Real-Time Object-Oriented Graphical User Interface for Control System Development

NASA Technical Reports Server (NTRS)

Litt, Jonathan; Wong, Edmond; Simon, Donald L.

1994-01-01

A prototype Lisp-based soft real-time object-oriented Graphical User Interface for control system development is presented. The Graphical User Interface executes alongside a test system in laboratory conditions to permit observation of the closed loop operation through animation, graphics, and text. Since it must perform interactive graphics while updating the screen in real time, techniques are discussed which allow quick, efficient data processing and animation. Examples from an implementation are included to demonstrate some typical functionalities which allow the user to follow the control system's operation.

A design strategy for autonomous systems

NASA Technical Reports Server (NTRS)

Forster, Pete

1989-01-01

Some solutions to crucial issues regarding the competent performance of an autonomously operating robot are identified; namely, that of handling multiple and variable data sources containing overlapping information and maintaining coherent operation while responding adequately to changes in the environment. Support for the ideas developed for the construction of such behavior are extracted from speculations in the study of cognitive psychology, an understanding of the behavior of controlled mechanisms, and the development of behavior-based robots in a few robot research laboratories. The validity of these ideas is supported by some simple simulation experiments in the field of mobile robot navigation and guidance.

Iris Transponder-Communications and Navigation for Deep Space

NASA Technical Reports Server (NTRS)

Duncan, Courtney B.; Smith, Amy E.; Aguirre, Fernando H.

2014-01-01

The Jet Propulsion Laboratory has developed the Iris CubeSat compatible deep space transponder for INSPIRE, the first CubeSat to deep space. Iris is 0.4 U, 0.4 kg, consumes 12.8 W, and interoperates with NASA's Deep Space Network (DSN) on X-Band frequencies (7.2 GHz uplink, 8.4 GHz downlink) for command, telemetry, and navigation. This talk discusses the Iris for INSPIRE, it's features and requirements; future developments and improvements underway; deep space and proximity operations applications for Iris; high rate earth orbit variants; and ground requirements, such as are implemented in the DSN, for deep space operations.

Design and implementation of a hospital-based usability laboratory: insights from a Department of Veterans Affairs laboratory for health information technology.

PubMed

Russ, Alissa L; Weiner, Michael; Russell, Scott A; Baker, Darrell A; Fahner, W Jeffrey; Saleem, Jason J

2012-12-01

Although the potential benefits of more usable health information technologies (HIT) are substantial-reduced HIT support costs, increased work efficiency, and improved patient safety--human factors methods to improve usability are rarely employed. The US Department of Veterans Affairs (VA) has emerged as an early leader in establishing usability laboratories to inform the design of HIT, including its electronic health record. Experience with a usability laboratory at a VA Medical Center provides insights on how to design, implement, and leverage usability laboratories in the health care setting. The VA Health Services Research and Development Service Human-Computer Interaction & Simulation Laboratory emerged as one of the first VA usability laboratories and was intended to provide research-based findings about HIT designs. This laboratory supports rapid prototyping, formal usability testing, and analysis tools to assess existing technologies, alternative designs, and potential future technologies. RESULTS OF IMPLEMENTATION: Although the laboratory has maintained a research focus, it has become increasingly integrated with VA operations, both within the medical center and on a national VA level. With this resource, data-driven recommendations have been provided for the design of HIT applications before and after implementation. The demand for usability testing of HIT is increasing, and information on how to develop usability laboratories for the health care setting is often needed. This article may assist other health care organizations that want to invest in usability resources to improve HIT. The establishment and utilization of usability laboratories in the health care setting may improve HIT designs and promote safe, high-quality care for patients.

Lessons Learned from the Puerto Rico Battery Energy Storage System

DOE Office of Scientific and Technical Information (OSTI.GOV)

BOYES, JOHN D.; DE ANA, MINDI FARBER; TORRES, WENCESLANO

1999-09-01

The Puerto Rico Electric Power Authority (PREPA) installed a distributed battery energy storage system in 1994 at a substation near San Juan, Puerto Rico. It was patterned after two other large energy storage systems operated by electric utilities in California and Germany. The U.S. Department of Energy (DOE) Energy Storage Systems Program at Sandia National Laboratories has followed the progress of all stages of the project since its inception. It directly supported the critical battery room cooling system design by conducting laboratory thermal testing of a scale model of the battery under simulated operating conditions. The Puerto Rico facility ismore » at present the largest operating battery storage system in the world and is successfully providing frequency control, voltage regulation, and spinning reserve to the Caribbean island. The system further proved its usefulness to the PREPA network in the fall of 1998 in the aftermath of Hurricane Georges. The owner-operator, PREPA, and the architect/engineer, vendors, and contractors learned many valuable lessons during all phases of project development and operation. In documenting these lessons, this report will help PREPA and other utilities in planning to build large energy storage systems.« less

Development of the HERMIES III mobile robot research testbed at Oak Ridge National Laboratory

DOE Office of Scientific and Technical Information (OSTI.GOV)

Manges, W.W.; Hamel, W.R.; Weisbin, C.R.

1988-01-01

The latest robot in the Hostile Environment Robotic Machine Intelligence Experiment Series (HERMIES) is now under development at the Center for Engineering Systems Advanced Research (CESAR) in the Oak Ridge National Laboratory. The HERMIES III robot incorporates a larger than human size 7-degree-of-freedom manipulator mounted on a 2-degree-of-freedom mobile platform including a variety of sensors and computers. The deployment of this robot represents a significant increase in research capabilities for the CESAR laboratory. The initial on-board computer capacity of the robot exceeds that of 20 Vax 11/780s. The navigation and vision algorithms under development make extensive use of the on-boardmore » NCUBE hypercube computer while the sensors are interfaced through five VME computers running the OS-9 real-time, multitasking operating system. This paper describes the motivation, key issues, and detailed design trade-offs of implementing the first phase (basic functionality) of the HERMIES III robot. 10 refs., 7 figs.« less

Occupational health hazards in the interventional laboratory: progress report of the Multispecialty Occupational Health Group.

PubMed

Miller, Donald L; Klein, Lloyd W; Balter, Stephen; Norbash, Alexander; Haines, David; Fairobent, Lynne; Goldstein, James A

2010-09-01

The Multispecialty Occupational Health Group (MSOHG), formed in 2005, is an informal coalition of societies representing professionals who work in, or are concerned with, interventional fluoroscopy. The group's long-term goals are to improve occupational health and operator and staff safety in the interventional laboratory while maintaining quality patient care and optimal use of the laboratory. MSOHG has conducted a dialogue with equipment manufacturers and has developed a list of specific objectives for research and development. The group has also represented the member societies in educating regulators, in educating interventionalists, and in fostering and collaborating on research into occupational health issues affecting interventionalists. Not least of the group's accomplishments, as a result of their collaboration in MSOHG, the group's members have developed a mutual respect that can serve as a basis for joint efforts in the future among interventionalists of different medical specialties. Copyright 2010 SIR. Published by Elsevier Inc. All rights reserved.

From the Research Laboratory to the Operating Company: How Information Travels.

ERIC Educational Resources Information Center

Coppin, Ann S.; Palmer, Linda L.

1980-01-01

Reviews transmission processes of Chevron Oil Field Research Company (COFRC) research results from laboratories to end-user operating companies worldwide. Information dissemination methods described included informal communication, intercompany meetings, visits by COFRC personnel to operating company offices, distribution of written reports,…

The NUITM-KEMRI P3 Laboratory in Kenya: Establishment, Features, Operation and Maintenance

PubMed Central

Inoue, Shingo; Wandera, Ernest; Miringu, Gabriel; Bundi, Martin; Narita, Chika; Ashur, Salame; Kwallah, Allan; Galata, Amina; Abubakar, Mwajuma; Suka, Sora; Mohamed, Shah; Karama, Mohamed; Horio, Masahiro; Shimada, Masaaki; Ichinose, Yoshio

2013-01-01

A biocontainment facility is a core component in any research setting due to the services it renders towards comprehensive biosafety observance. The NUITM-KEMRI P3 facility was set up in 2007 and has been actively in use since 2010 by researchers from this and other institutions. A number of hazardous agents have been handled in the laboratory among them MDR-TB and yellow fever viruses. The laboratory has the general physical and operational features of a P3 laboratory in addition to a number of unique features, among them the water-air filtration system, the eco-mode operation feature and automation of the pressure system that make the facility more efficient. It is equipped with biosafety and emergency response equipments alongside common laboratory equipments, maintained regularly using daily, monthly and yearly routines. Security and safety is strictly observed within the facility, enhanced by restricted entry, strict documentation and use of safety symbols. Training is also engrained within the operation of the laboratory and is undertaken and evaluated annually. Though the laboratory is in the process of obtaining accreditation, it is fully certified courtesy of the manufactures’ and constructed within specified standards. PMID:23533023

Incorporating Safety into a Unit Operations Laboratory Course.

ERIC Educational Resources Information Center

King, Julia A.

1998-01-01

Details the incorporation of safety procedures and issues into the curriculum of an undergraduate chemical engineering unit operations laboratory course. Includes checklists and sample reporting forms. (DDR)