Sample records for diagnostic flow chart

  1. Evaluation of a diagnostic flow chart applying medical thoracoscopy, adenosine deaminase and T-SPOT.TB in diagnosis of tuberculous pleural effusion.

    PubMed

    He, Y; Zhang, W; Huang, T; Wang, X; Wang, M

    2015-10-01

    To evaluate a diagnostic flow chart applying medical thoracoscoy (MT), adenosine deaminase (ADA) and T-SPOT.TB in diagnosis of tuberculous pleural effusion (TPE) at a high TB burden country. 136 patients with pleural effusion (PE) were enrolled and divided into TPE and Non-TPE group. MT (histology), PE ADA and T-SPOT.TB were conducted on all patients. ROC analysis was performed for the best cut-off value of PE ADA in detection of TPE. The diagnostic flow chart applying MT, ADA and T-SPOT.TB was evaluated for improving the limitations of each diagnostic method. ROC analysis showed that the best cut-off value of PE ADA was 30U/L. The sensitivity and specificity of these tests were calculated respectively to be: 71.4% (58.5%-81.6%) and 100% (95.4-100.0%) for MT, 92.9% (83.0-97.2%) and 68.8% (57.9-77.9%) for T-SPOT.TB, and 80.0% (69.6-88.1%) and 92.9% (82.7-98.0%) for PE ADA. The sensitivity, specificity, positive likelihood ratio, negative likelihood ratio, positive predictive value and negative predictive value of the diagnostic flow chart were 96.4% (87.9-99.0%), 96.3% (89.6-98.7%), 25.714, 0.037, 97.4 and 94.9, respectively. The diagnostic flow chart applying MT, ADA and T-SPOT.TB is an accurate and rapid diagnostic method in detection of TPE.

  2. Computer assisted uroflowmetry diagnostic system

    NASA Astrophysics Data System (ADS)

    Makal, Jarosław; Idźkowski, Adam; Walendziuk, Wojciech

    2006-10-01

    In this paper an original uroflowmeter (called Adalbertus) has been presented. The device draws the flow chart and measures the parameters of urine flow. It is used in urological surgeries as an assistance in diagnosis of lower urinary track diseases like Benign Prostatic Hyperplasia (BPH). The measuring track and its main part - weight sensor have been described. Also the way of uncertainty calculation is mentioned. An example flow chart has been shown and the achieved results have been compared with a commercial product.

  3. An algorithmic approach to the brain biopsy--part I.

    PubMed

    Kleinschmidt-DeMasters, B K; Prayson, Richard A

    2006-11-01

    The formulation of appropriate differential diagnoses for a slide is essential to the practice of surgical pathology but can be particularly challenging for residents and fellows. Algorithmic flow charts can help the less experienced pathologist to systematically consider all possible choices and eliminate incorrect diagnoses. They can assist pathologists-in-training in developing orderly, sequential, and logical thinking skills when confronting difficult cases. To present an algorithmic flow chart as an approach to formulating differential diagnoses for lesions seen in surgical neuropathology. An algorithmic flow chart to be used in teaching residents. Algorithms are not intended to be final diagnostic answers on any given case. Algorithms do not substitute for training received from experienced mentors nor do they substitute for comprehensive reading by trainees of reference textbooks. Algorithmic flow diagrams can, however, direct the viewer to the correct spot in reference texts for further in-depth reading once they hone down their diagnostic choices to a smaller number of entities. The best feature of algorithms is that they remind the user to consider all possibilities on each case, even if they can be quickly eliminated from further consideration. In Part I, we assist the resident in learning how to handle brain biopsies in general and how to distinguish nonneoplastic lesions that mimic tumors from true neoplasms.

  4. An algorithmic approach to the brain biopsy--part II.

    PubMed

    Prayson, Richard A; Kleinschmidt-DeMasters, B K

    2006-11-01

    The formulation of appropriate differential diagnoses for a slide is essential to the practice of surgical pathology but can be particularly challenging for residents and fellows. Algorithmic flow charts can help the less experienced pathologist to systematically consider all possible choices and eliminate incorrect diagnoses. They can assist pathologists-in-training in developing orderly, sequential, and logical thinking skills when confronting difficult cases. To present an algorithmic flow chart as an approach to formulating differential diagnoses for lesions seen in surgical neuropathology. An algorithmic flow chart to be used in teaching residents. Algorithms are not intended to be final diagnostic answers on any given case. Algorithms do not substitute for training received from experienced mentors nor do they substitute for comprehensive reading by trainees of reference textbooks. Algorithmic flow diagrams can, however, direct the viewer to the correct spot in reference texts for further in-depth reading once they hone down their diagnostic choices to a smaller number of entities. The best feature of algorithms is that they remind the user to consider all possibilities on each case, even if they can be quickly eliminated from further consideration. In Part II, we assist the resident in arriving at the correct diagnosis for neuropathologic lesions containing granulomatous inflammation, macrophages, or abnormal blood vessels.

  5. Sinus pericranii: diagnosis and management in 21 pediatric patients.

    PubMed

    Pavanello, Marco; Melloni, Ilaria; Antichi, Eleonora; Severino, Mariasavina; Ravegnani, Marcello; Piatelli, Gianluca; Cama, Armando; Rossi, Andrea; Gandolfo, Carlo

    2015-01-01

    Sinus pericranii (SP) is a rare venous anomaly abnormally connecting the intracranial dural sinuses with the epicranial veins. In the present study the authors aimed to clarify this clinicoradiological entity, define the role of angiography in its preoperative assessment, and suggest a diagnostic-therapeutic flow chart for management purposes. The authors retrospectively reviewed the clinical charts and neuroimages of 21 patients with SP. All patients underwent brain MRI, MR venography, and craniocerebral CT. Diagnostic digital subtraction angiography was performed in 19 of 21 patients, and the SPs were categorized as dominant (draining the majority of the intracranial venous outflow) or accessory (draining only a minority of the intracranial venous outflow). SP was median or paramedian in 20 patients and lateral in 1 patient. There were 5 dominant and 14 accessory SPs. The dominant SPs were not treated. Among the patients with accessory SP, 4 were not treated, 2 underwent surgical ligature, and 8 were treated endovascularly (with either transvenous or percutaneous embolization). No complications were observed, and symptoms disappeared after treatment in all cases. Accepted guidelines or recommendations concerning the management, diagnosis, and treatment of SP are still lacking. The authors define here a diagnostic-therapeutic flow chart, in which angiography plays a crucial role in the classification of SP and choice of the optimal treatment. Only accessory SP is amenable to treatment, whereas dominant SP must be preserved. The endovascular approach is becoming increasingly relevant and has proven to be safe and effective.

  6. Automatic Target Recognition Classification System Evaluation Methodology

    DTIC Science & Technology

    2002-09-01

    Testing Set of Two-Class XOR Data (250 Samples)......................................... 2-59 2.27 Decision Analysis Process Flow Chart...ROC curve meta - analysis , which is the estimation of the true ROC curve of a given diagnostic system through ROC analysis across many studies or...technique can be very effective in sensitivity analysis ; trying to determine which data points have the most effect on the solution, and in

  7. Umbilical venous catheters placement evaluation on frontal radiogram: application of a simplified flow-chart for radiology residents.

    PubMed

    Salerno, Sergio; Tudisca, Chiara; Murmura, Elena; Matranga, Domenica; La Tona, Giuseppe; Lo Re, Giuseppe; Lo Casto, Antonio

    2017-05-01

    Umbilical Venous Catheter (UVC) are commonly used in neonatal period; they can be not correctly positioned and could be associated with complications. The purpose of this article is to suggest a flow-chart to evaluate the placement of UVC, testing it in young radiologists-in-training. We developed a simple flow-chart to asses, steps by step, UVC placement considering its course and tip location (ideally placed in the atriocaval junction). We tested the flow-chart impact asking to 20 residents to evaluate the placement of 10 UVC before and after they familiarized with the flow-chart and the anatomical findings of a newborn. The agreement among the 20 students was evaluated too. The number of correct characterizations was different due to the administration of the flow-chart. One hundred and six correct UVC assessments at the beginning switched to 196 after the administration of the flow-chart (p = 0.0001). The observed agreement among the twenty radiology residents was statistically significant, both before (kappa = 0.41, p < 0.001) and after (kappa = 0.37, p < 0.001) the flow-chart administration. The developed flow-chart demonstrated to be useful in increasing residents performance in UVC placement assessment.

  8. The Use of Flow Charts in Sediment Routing Analysis

    Treesearch

    Leslie M. Reid

    1982-01-01

    Flow charts are a widely used means of diagramming relationships among transport processes and storage sites during analyses of sediment routing. Because they have taken so many different forms, however, it is very difficult to use published flow charts to compare geomorphic systems. Though they generally are constructed to achieve the same purpose, flow charts...

  9. Diagnostic Value of Run Chart Analysis: Using Likelihood Ratios to Compare Run Chart Rules on Simulated Data Series

    PubMed Central

    Anhøj, Jacob

    2015-01-01

    Run charts are widely used in healthcare improvement, but there is little consensus on how to interpret them. The primary aim of this study was to evaluate and compare the diagnostic properties of different sets of run chart rules. A run chart is a line graph of a quality measure over time. The main purpose of the run chart is to detect process improvement or process degradation, which will turn up as non-random patterns in the distribution of data points around the median. Non-random variation may be identified by simple statistical tests including the presence of unusually long runs of data points on one side of the median or if the graph crosses the median unusually few times. However, there is no general agreement on what defines “unusually long” or “unusually few”. Other tests of questionable value are frequently used as well. Three sets of run chart rules (Anhoej, Perla, and Carey rules) have been published in peer reviewed healthcare journals, but these sets differ significantly in their sensitivity and specificity to non-random variation. In this study I investigate the diagnostic values expressed by likelihood ratios of three sets of run chart rules for detection of shifts in process performance using random data series. The study concludes that the Anhoej rules have good diagnostic properties and are superior to the Perla and the Carey rules. PMID:25799549

  10. Decompressive craniectomy and hydrocephalus: proposal of a therapeutic flow chart.

    PubMed

    Peraio, Simone; Calcagni, Maria Lucia; Mattoli, Maria Vittoria; Marziali, Giammaria; DE Bonis, Pasquale; Pompucci, Angelo; Anile, Carmelo; Mangiola, Annunziato

    2017-12-01

    Decompressive craniectomy (DC) may be necessary to save the lives of patients suffering from intracranial hypertension. However, this procedure is not complication-free. Its two main complications are hydrocephalus and the sinking skin-flap syndrome (SSFS). The radiological findings and the clinical evaluation may be not enough to decide when and/or how to treat hydrocephalus in a decompressed patient. SSFS and hydrocephalus may be not unrelated. In fact, a patient affected by hydrocephalus, after the ventriculo-peritoneal shunt, can develop SSFS; on the other hand, SSFS per se can cause hydrocephalus. Treating hydrocephalus in decompressed patients can be challenging. Radiological findings and clinical evaluation may not be enough to define the most appropriate therapeutic strategy. Cerebrospinal fluid (CSF) dynamics and metabolic evaluations can represent important diagnostic tools for assessing the need of a CSF shunt in patients with a poor baseline neurologic status. Based on our experience, we propose a flow chart for treating decompressed patients affected by ventriculomegaly.

  11. Differential diagnosis and diagnostic flow chart of joint hypermobility syndrome/ehlers-danlos syndrome hypermobility type compared to other heritable connective tissue disorders.

    PubMed

    Colombi, Marina; Dordoni, Chiara; Chiarelli, Nicola; Ritelli, Marco

    2015-03-01

    Joint hypermobility syndrome/Ehlers-Danlos syndrome hypermobility type (JHS/EDS-HT) is an evolving and protean disorder mostly recognized by generalized joint hypermobility and without a defined molecular basis. JHS/EDS-HT also presents with other connective tissue features affecting a variety of structures and organs, such as skin, eye, bone, and internal organs. However, most of these signs are present in variable combinations and severity in many other heritable connective tissue disorders. Accordingly, JHS/EDS-HT is an "exclusion" diagnosis which needs the absence of any consistent feature indicative of other partially overlapping connective tissue disorders. While both Villefranche and Brighton criteria include such an exclusion as a mandatory item, a systematic approach for reaching a stringent clinical diagnosis of JHS/EDS-HT is still lacking. The absence of a consensus on the diagnostic approach to JHS/EDS-HT concerning its clinical boundaries with similar conditions contribute to limit our actual understanding of the pathologic and molecular bases of this disorder. In this review, we revise the differential diagnosis of JHS/EDS-HT with those heritable connective tissue disorders which show a significant overlap with the former and mostly include EDS classic, vascular and kyphoscoliotic types, osteogenesis imperfecta, Marfan syndrome, Loeys-Dietz syndrome, arterial tortuosity syndrome, and lateral meningocele syndrome. A diagnostic flow chart is also offered with the attempt to support the less experienced clinician in stringently recognizing JHS/EDS-HT and stimulate the debate in the scientific community for both management and research purposes. © 2015 Wiley Periodicals, Inc.

  12. Predictive ability and efficacy for shortening door-to-balloon time of a new prehospital electrocardiogram-transmission flow chart in patients with ST-elevation myocardial infarction - Results of the CASSIOPEIA study.

    PubMed

    Sakai, Toshiaki; Nishiyama, Osamu; Onodera, Masayuki; Matsuda, Shigekatsu; Wakisawa, Shinobu; Nakamura, Motoyuki; Morino, Yoshihiro; Itoh, Tomonori

    2018-05-24

    The purposes of this study were to create a new flow-chart of prehospital electrocardiography (ECG)-transmission, evaluate its predictive ability for ST-elevation myocardial infarction (STEMI) and shorten door-to-balloon time (DTBT). The new transmission flow-chart was created using symptoms from previous medical records of STEMI patients. A total of 4090 consecutive patients transferred emergently to our hospital were divided into two groups: those in ambulances with an ECG-transmission device with the new flow-chart (ECGT-FC) and those transferred without an ECG-transmission device (non-ECGT) groups. A STEMI group comprising walk-in patients during the same period was used as a control group. The predictive ability of STEMI and the effectiveness of shortening the DTBT by the new flow-chart of ECG-transmission was evaluated. In the ECGT-FC group, the prevalence of STEMI in the ECG-transmission by the new flow-chart were significantly higher than in the non-ECG-transmission patients (6.71% vs. 0.19%; p<0.001). The sensitivity and specificity of the new ECG-transmission flow-chart were 83.3% and 88.1%, respectively. The median DTBT was significantly shortened (p=0.045) and the prevalence of DTBT<90min was significantly higher in the ECGT-FC group (p=0.018) than the other groups. The sensitivity and specificity of the new flow-chart for ECG-transmission were high. The new flow-chart combined with an ECG-transmission device could detect STEMI efficiently and shorten DTBT. Copyright © 2018 Japanese College of Cardiology. Published by Elsevier Ltd. All rights reserved.

  13. Glucose-6-phosphate dehydrogenase laboratory assay: How, when, and why?

    PubMed

    Minucci, Angelo; Giardina, Bruno; Zuppi, Cecilia; Capoluongo, Ettore

    2009-01-01

    Glucose 6-phosphate dehydrogenase (G6PD) deficiency is the most common defect of red blood cells. Although some different laboratory techniques or methods are employed for the biochemical screening, a strict relationship between biochemists, clinicians, and molecular biologists is necessary for a definitive diagnosis. This article represents an overview on the current laboratory tests finalized to the screening or to the definitive diagnosis of G6PD-deficiency, underlying the problems regarding the biochemical and molecular identification of heterozygote females other than those regarding the standardization of the clinical and laboratory diagnostic procedures. Finally, this review is aimed to give a flow-chart for the complete diagnostic approach of G6PD-deficiency.

  14. Flow Charts: Visualization of Vector Fields on Arbitrary Surfaces

    PubMed Central

    Li, Guo-Shi; Tricoche, Xavier; Weiskopf, Daniel; Hansen, Charles

    2009-01-01

    We introduce a novel flow visualization method called Flow Charts, which uses a texture atlas approach for the visualization of flows defined over curved surfaces. In this scheme, the surface and its associated flow are segmented into overlapping patches, which are then parameterized and packed in the texture domain. This scheme allows accurate particle advection across multiple charts in the texture domain, providing a flexible framework that supports various flow visualization techniques. The use of surface parameterization enables flow visualization techniques requiring the global view of the surface over long time spans, such as Unsteady Flow LIC (UFLIC), particle-based Unsteady Flow Advection Convolution (UFAC), or dye advection. It also prevents visual artifacts normally associated with view-dependent methods. Represented as textures, Flow Charts can be naturally integrated into hardware accelerated flow visualization techniques for interactive performance. PMID:18599918

  15. BASIC Language Flow Charting Program (BASCHART). Technical Note 3-82.

    ERIC Educational Resources Information Center

    Johnson, Charles C.; And Others

    This document describes BASCHART, a computer aid designed to decipher and automatically flow chart computer program logic; it also provides the computer code necessary for this process. Developed to reduce the labor intensive manual process of producing a flow chart for an undocumented or inadequately documented program, BASCHART will…

  16. Formulae and Flow-Diagrams

    ERIC Educational Resources Information Center

    Willson, William Wynne

    1977-01-01

    The author recommends the use of flow charting to help students understand the manipulation of algebraic formulae. He identifies some problems with flow charts and suggests an alternative method of constructing flow diagrams. (SD)

  17. How to Read an LLNL Energy Flow Chart (Sankey Diagram)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Simon, A. J.

    Each year, the Lawrence Livermore National Laboratory releases energy flow charts that illustrate the nation's consumption and use of energy. A.J. Simon, group leader for LLNL’s energy program, breaks the 2015 chart down in this video, describing how to read the chart and what year-to-year trends he sees.

  18. Control of Technology Transfer at JPL

    NASA Technical Reports Server (NTRS)

    Oliver, Ronald

    2006-01-01

    Controlled Technology: 1) Design: preliminary or critical design data, schematics, technical flow charts, SNV code/diagnostics, logic flow diagrams, wirelist, ICDs, detailed specifications or requirements. 2) Development: constraints, computations, configurations, technical analyses, acceptance criteria, anomaly resolution, detailed test plans, detailed technical proposals. 3) Production: process or how-to: assemble, operated, repair, maintain, modify. 4) Manufacturing: technical instructions, specific parts, specific materials, specific qualities, specific processes, specific flow. 5) Operations: how-to operate, contingency or standard operating plans, Ops handbooks. 6) Repair: repair instructions, troubleshooting schemes, detailed schematics. 7) Test: specific procedures, data, analysis, detailed test plan and retest plans, detailed anomaly resolutions, detailed failure causes and corrective actions, troubleshooting, trended test data, flight readiness data. 8) Maintenance: maintenance schedules and plans, methods for regular upkeep, overhaul instructions. 9) Modification: modification instructions, upgrades kit parts, including software

  19. How to Read an LLNL Energy Flow Chart (Sankey Diagram)

    ScienceCinema

    Simon, A. J.

    2018-01-16

    Each year, the Lawrence Livermore National Laboratory releases energy flow charts that illustrate the nation's consumption and use of energy. A.J. Simon, group leader for LLNL’s energy program, breaks the 2015 chart down in this video, describing how to read the chart and what year-to-year trends he sees.

  20. School Mathematics Study Group, Unit Number Two. Chapter 3 - Informal Algorithms and Flow Charts. Chapter 4 - Applications and Mathematics Models.

    ERIC Educational Resources Information Center

    Stanford Univ., CA. School Mathematics Study Group.

    This is the second unit of a 15-unit School Mathematics Study Group (SMSG) mathematics text for high school students. Topics presented in the first chapter (Informal Algorithms and Flow Charts) include: changing a flat tire; algorithms, flow charts, and computers; assignment and variables; input and output; using a variable as a counter; decisions…

  1. 21 CFR 886.1150 - Visual acuity chart.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Visual acuity chart. 886.1150 Section 886.1150 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES OPHTHALMIC DEVICES Diagnostic Devices § 886.1150 Visual acuity chart. (a) Identification...

  2. Energy measurement using flow computers and chromatography

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Beeson, J.

    1995-12-01

    Arkla Pipeline Group (APG), along with most transmission companies, went to electronic flow measurement (EFM) to: (1) Increase resolution and accuracy; (2) Real time correction of flow variables; (3) Increase speed in data retrieval; (4) Reduce capital expenditures; and (5) Reduce operation and maintenance expenditures Prior to EFM, mechanical seven day charts were used which yielded 800 pressure and differential pressure readings. EFM yields 1.2-million readings, a 1500 time improvement in resolution and additional flow representation. The total system accuracy of the EFM system is 0.25 % compared with 2 % for the chart system which gives APG improved accuracy.more » A typical APG electronic measurement system includes a microprocessor-based flow computer, a telemetry communications package, and a gas chromatograph. Live relative density (specific gravity), BTU, CO{sub 2}, and N{sub 2} are updated from the chromatograph to the flow computer every six minutes which provides accurate MMBTU computations. Because the gas contract length has changed from years to monthly and from a majority of direct sales to transports both Arkla and its customers wanted access to actual volumes on a much more timely basis than is allowed with charts. The new electronic system allows volumes and other system data to be retrieved continuously, if EFM is on Supervisory Control and Data Acquisition (SCADA) or daily if on dial up telephone. Previously because of chart integration, information was not available for four to six weeks. EFM costs much less than the combined costs of telemetry transmitters, pressure and differential pressure chart recorders, and temperature chart recorder which it replaces. APG will install this equipment on smaller volume stations at a customers expense. APG requires backup measurement on metering facilities this size. It could be another APG flow computer or chart recorder, or the other companies flow computer or chart recorder.« less

  3. Diagnostic precision of mentally estimated home blood pressure means.

    PubMed

    Ouattara, Franck Olivier; Laskine, Mikhael; Cheong, Nathalie Ng; Birnbaum, Leora; Wistaff, Robert; Bertrand, Michel; van Nguyen, Paul; Kolan, Christophe; Durand, Madeleine; Rinfret, Felix; Lamarre-Cliche, Maxime

    2018-05-07

    Paper home blood pressure (HBP) charts are commonly brought to physicians at office visits. The precision and accuracy of mental calculations of blood pressure (BP) means are not known. A total of 109 hypertensive patients were instructed to measure and record their HBP for 1 week and to bring their paper charts to their office visit. Study section 1: HBP means were calculated electronically and compared to corresponding in-office BP estimates made by physicians. Study section 2: 100 randomly ordered HBP charts were re-examined repetitively by 11 evaluators. Each evaluator estimated BP means four times in 5, 15, 30, and 60 s (random order) allocated for the task. BP means and diagnostic performance (determination of therapeutic systolic and diastolic BP goals attained or not) were compared between physician estimates and electronically calculated results. Overall, electronically and mentally calculated BP means were not different. Individual analysis showed that 83% of in-office physician estimates were within a 5-mmHg systolic BP range. There was diagnostic disagreement in 15% of cases. Performance improved consistently when the time allocated for BP estimation was increased from 5 to 15 s and from 15 to 30 s, but not when it exceeded 30 s. Mentally calculating HBP means from paper charts can cause a number of diagnostic errors. Chart evaluation exceeding 30 s does not significantly improve accuracy. BP-measuring devices with modern analytical capacities could be useful to physicians.

  4. Screening pregnant women for suicidal behavior in electronic medical records: diagnostic codes vs. clinical notes processed by natural language processing.

    PubMed

    Zhong, Qiu-Yue; Karlson, Elizabeth W; Gelaye, Bizu; Finan, Sean; Avillach, Paul; Smoller, Jordan W; Cai, Tianxi; Williams, Michelle A

    2018-05-29

    We examined the comparative performance of structured, diagnostic codes vs. natural language processing (NLP) of unstructured text for screening suicidal behavior among pregnant women in electronic medical records (EMRs). Women aged 10-64 years with at least one diagnostic code related to pregnancy or delivery (N = 275,843) from Partners HealthCare were included as our "datamart." Diagnostic codes related to suicidal behavior were applied to the datamart to screen women for suicidal behavior. Among women without any diagnostic codes related to suicidal behavior (n = 273,410), 5880 women were randomly sampled, of whom 1120 had at least one mention of terms related to suicidal behavior in clinical notes. NLP was then used to process clinical notes for the 1120 women. Chart reviews were performed for subsamples of women. Using diagnostic codes, 196 pregnant women were screened positive for suicidal behavior, among whom 149 (76%) had confirmed suicidal behavior by chart review. Using NLP among those without diagnostic codes, 486 pregnant women were screened positive for suicidal behavior, among whom 146 (30%) had confirmed suicidal behavior by chart review. The use of NLP substantially improves the sensitivity of screening suicidal behavior in EMRs. However, the prevalence of confirmed suicidal behavior was lower among women who did not have diagnostic codes for suicidal behavior but screened positive by NLP. NLP should be used together with diagnostic codes for future EMR-based phenotyping studies for suicidal behavior.

  5. Results of a multicentre randomised controlled trial of statistical process control charts and structured diagnostic tools to reduce ward-acquired meticillin-resistant Staphylococcus aureus: the CHART Project.

    PubMed

    Curran, E; Harper, P; Loveday, H; Gilmour, H; Jones, S; Benneyan, J; Hood, J; Pratt, R

    2008-10-01

    Statistical process control (SPC) charts have previously been advocated for infection control quality improvement. To determine their effectiveness, a multicentre randomised controlled trial was undertaken to explore whether monthly SPC feedback from infection control nurses (ICNs) to healthcare workers of ward-acquired meticillin-resistant Staphylococcus aureus (WA-MRSA) colonisation or infection rates would produce any reductions in incidence. Seventy-five wards in 24 hospitals in the UK were randomised into three arms: (1) wards receiving SPC chart feedback; (2) wards receiving SPC chart feedback in conjunction with structured diagnostic tools; and (3) control wards receiving neither type of feedback. Twenty-five months of pre-intervention WA-MRSA data were compared with 24 months of post-intervention data. Statistically significant and sustained decreases in WA-MRSA rates were identified in all three arms (P<0.001; P=0.015; P<0.001). The mean percentage reduction was 32.3% for wards receiving SPC feedback, 19.6% for wards receiving SPC and diagnostic feedback, and 23.1% for control wards, but with no significant difference between the control and intervention arms (P=0.23). There were significantly more post-intervention 'out-of-control' episodes (P=0.021) in the control arm (averages of 0.60, 0.28, and 0.28 for Control, SPC and SPC+Tools wards, respectively). Participants identified SPC charts as an effective communication tool and valuable for disseminating WA-MRSA data.

  6. A novel diagram and complement to the CONSORT chart for presenting multimodal clinical trials.

    PubMed

    Schuller, Jan C; Mayer, Michael; Lanz, Doris; Schmitz, Shu-Fang Hsu; Brauchli, Peter; Leupin, Nicolas

    2009-05-01

    We developed a novel diagram to depict patient flow and outcomes in clinical trials. In contrast to flow diagrams such as the CONSORT chart, our diagram enables individual patient histories to be traced and depicts important patterns of treatment administration and outcomes, such as response and adverse events. Also, it is particularly useful for multimodal treatments or a sequence of different therapies where the CONSORT flow chart is less informative and can be confusing.

  7. Experimenting With Ore: Creating the Taconite Process; flow chart of ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Experimenting With Ore: Creating the Taconite Process; flow chart of process - Mines Experiment Station, University of Minnesota, Twin Cities Campus, 56 East River Road, Minneapolis, Hennepin County, MN

  8. [Prospective comparison of the flow chart for laboratory investigations for anaemia from the Dutch College of General Practitioners' guideline 'Anaemia' with a self-developed, substantive and logistical alternative flow chart].

    PubMed

    Oosterhuis, W P; van der Horst, M; van Dongen, K; Ulenkate, H J L M; Volmer, M; Wulkan, R W

    2007-10-20

    To compare the flow diagram for the diagnosis of anaemia from the guideline 'Anaemia' from the Dutch College of General Practitioners (NHG) with a substantive and logistical alternative protocol. Prospective. For evaluation of anaemia, 124 patients from primary care reported to the laboratories of the St. Elisabeth Hospital in Tilburg (n = 94) and the Scheper Hospital in Emmen (n = 30), the Netherlands. Two flow charts were used: the NHG's flow chart and a self-developed chart in which not mean corpuscular volume, but ferritin concentration occupies the central position. All the laboratory tests mentioned in both flow charts were carried out in every patient with, for practical reasons, the exception of Hgb electrophoresis and bone marrow investigations. General practitioners were approached and patient dossiers were consulted to obtain further clinical data. According to the NHG protocol, on the grounds of the laboratory investigations, 64 (52%) of patients could not be put in a specific category. The majority were patients with normocytary anaemia who did not fulfil the criteria for iron deficiency anaemia or the anaemia of chronic disease. According to the alternative chart, in 36 (29%) patients no diagnosis was made. These were patients in whom no abnormal laboratory findings were observed, other than low haemoglobin values. The majority of the patients had normocytary anaemia, in some cases this was interpreted as the anaemia of chronic disease, but more often the anaemia could not be assigned to a particular category. A large number ofpatients had a raised creatinine value. This value did not appear in the NHG protocol. In 15% of patients, more than one cause for anaemia was found. The NHG protocol did not enable these multiple diagnoses to be made. Accordingly, the NHG protocol was difficult to implement in the laboratory. Using the NHG flow diagram a large percentage of patients could not be assigned to a particular category. Using the alternative flow diagram, which procedure is easier to carry out in the laboratory, it was possible to make multiple diagnoses.

  9. 23 CFR Appendix D to Subpart D of... - Equal Opportunity Compliance Review Process Flow Chart

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 23 Highways 1 2010-04-01 2010-04-01 false Equal Opportunity Compliance Review Process Flow Chart D Appendix D to Subpart D of Part 230 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION..., Subpt. D, App. D Appendix D to Subpart D of Part 230—Equal Opportunity Compliance Review Process Flow...

  10. Usefulness of a Regional Health Care Information System in primary care: a case study.

    PubMed

    Maass, Marianne C; Asikainen, Paula; Mäenpää, Tiina; Wanne, Olli; Suominen, Tarja

    2008-08-01

    The goal of this paper is to describe some benefits and possible cost consequences of computer based access to specialised health care information. A before-after activity analysis regarding 20 diabetic patients' clinical appointments was performed in a Health Centre in Satakunta region in Finland. Cost data, an interview, time-and-motion studies, and flow charts based on modelling were applied. Access to up-to-date diagnostic information reduced redundant clinical re-appointments, repeated tests, and mail orders for missing data. Timely access to diagnostic information brought about several benefits regarding workflow, patient care, and disease management. These benefits resulted in theoretical net cost savings. The study results indicated that Regional Information Systems may be useful tools to support performance and improve efficiency. However, further studies are required in order to verify how the monetary savings would impact the performance of Health Care Units.

  11. Unstop the Logjams in Your Cash Flow.

    ERIC Educational Resources Information Center

    Everett, R. E.

    1989-01-01

    A cash flow analysis is charting expenditures and revenues against a factor of time. Explains how school systems can, by charting the congruency of revenues and expenditures carefully, develop an investment program to take maximum advantage of a positive cash position. (MLF)

  12. The stability cycle—A universal pathway for the stability of films over topography

    NASA Astrophysics Data System (ADS)

    Schörner, Mario; Aksel, Nuri

    2018-01-01

    In the present study on the linear stability of gravity-driven Newtonian films flowing over inclined topographies, we consider a fundamental question: Is there a universal principle, being valid to describe the parametric evolution of the flow's stability chart for variations of different system parameters? For this sake, we first screened all experimental and numerical stability charts available in the literature. In a second step, we performed experiments to fill the gaps which remained. Variations of the fluid's viscosity and the topography's specific shape, amplitude, wavelength, tip width, and inclination were considered. That way, we identified a set of six characteristic patterns of stability charts to be sufficient to describe and unify all results on the linear stability of Newtonian films flowing over undulated inclines. We unveiled a universal pathway—the stability cycle—along which the linear stability charts of all considered Newtonian films flowing down periodically corrugated inclines evolved when the system parameters were changed.

  13. AMPS data management requirements study, appendix 1. [user manuals (computer programs)/display devices - computerized simulation/experimentation/ionosphere

    NASA Technical Reports Server (NTRS)

    1975-01-01

    Flow charts and display formats for the simulation of five experiments are given. The experiments are: (1) electromagnetic wave transmission; (2) passive observations of ambient plasma; (3) ionospheric measurements with subsatellite; (4) electron accelerator beam measurements; and (5) measurement of acoustical gravity waves in the sodium layer using lasers. A detailed explanation of the simulation procedure, definition of variables, and an explanation of how the experimenter makes display choices is also presented. A functional description is included on each flow chart and the assumptions and definitions of terms and scope of the flow charts and displays are presented.

  14. Design and performance of a large vocabulary discrete word recognition system. Volume 2: Appendixes. [flow charts and users manual

    NASA Technical Reports Server (NTRS)

    1973-01-01

    The users manual for the word recognition computer program contains flow charts of the logical diagram, the memory map for templates, the speech analyzer card arrangement, minicomputer input/output routines, and assembly language program listings.

  15. Honors: Getting Started.

    ERIC Educational Resources Information Center

    Etheridge, Sandra Y.

    This paper provides a description of the development of an honors program at Gulf Coast Community College (GCCC). The description is organized around three flow charts corresponding to different stages in the program's development, and which are followed by more detailed explanations. The first flow chart deals with program planning and…

  16. Recommendations on nuclear and multimodality imaging in IE and CIED infections.

    PubMed

    Erba, Paola Anna; Lancellotti, Patrizio; Vilacosta, Isidre; Gaemperli, Oliver; Rouzet, Francois; Hacker, Marcus; Signore, Alberto; Slart, Riemer H J A; Habib, Gilbert

    2018-05-24

    In the latest update of the European Society of Cardiology (ESC) guidelines for the management of infective endocarditis (IE), imaging is positioned at the centre of the diagnostic work-up so that an early and accurate diagnosis can be reached. Besides echocardiography, contrast-enhanced CT (ce-CT), radiolabelled leucocyte (white blood cell, WBC) SPECT/CT and [ 18 F]FDG PET/CT are included as diagnostic tools in the diagnostic flow chart for IE. Following the clinical guidelines that provided a straightforward message on the role of multimodality imaging, we believe that it is highly relevant to produce specific recommendations on nuclear multimodality imaging in IE and cardiac implantable electronic device infections. In these procedural recommendations we therefore describe in detail the technical and practical aspects of WBC SPECT/CT and [ 18 F]FDG PET/CT, including ce-CT acquisition protocols. We also discuss the advantages and limitations of each procedure, specific pitfalls when interpreting images, and the most important results from the literature, and also provide recommendations on the appropriate use of multimodality imaging.

  17. Flow Chart for Mineral Separation from Granitic Rocks.

    ERIC Educational Resources Information Center

    Mursky, Gregory

    1987-01-01

    Provided is a flow chart for the separation and purification of major, minor, and accessory minerals from granitic rocks. With careful use of heavy liquids, and a Franz Isodynamic Magnetic Separator, it is possible to obtain mineral concentrates with a purity of 95 percent or better. (Author/RH)

  18. SeaWiFS Science Algorithm Flow Chart

    NASA Technical Reports Server (NTRS)

    Darzi, Michael

    1998-01-01

    This flow chart describes the baseline science algorithms for the Sea-viewing Wide Field-of-view Sensor (SeaWiFS) Data Processing System (SDPS). As such, it includes only processing steps used in the generation of the operational products that are archived by NASA's Goddard Space Flight Center (GSFC) Distributed Active Archive Center (DAAC). It is meant to provide the reader with a basic understanding of the scientific algorithm steps applied to SeaWiFS data. It does not include non-science steps, such as format conversions, and places the greatest emphasis on the geophysical calculations of the level-2 processing. Finally, the flow chart reflects the logic sequences and the conditional tests of the software so that it may be used to evaluate the fidelity of the implementation of the scientific algorithm. In many cases however, the chart may deviate from the details of the software implementation so as to simplify the presentation.

  19. Flow Charts for Determining Your Requirements: Nine Metal Fabrication and Finishing Source Categories Area Sources National Emission Standards for Hazardous Air Pollutants (NESHAP) Subpart XXXXXX

    EPA Pesticide Factsheets

    This page contains a July 2008 document that has flow charts to help determine if this National Emission Standards for Hazardous Air Pollutants (NESHAP) rule for Nine metal Fabrication and Finishing Area Source Categories applies to your facility.

  20. Problem Solving in a Middle School Robotics Design Classroom

    NASA Astrophysics Data System (ADS)

    Norton, Stephen J.; McRobbie, Campbell J.; Ginns, Ian S.

    2007-07-01

    Little research has been conducted on how students work when they are required to plan, build and evaluate artefacts in technology rich learning environments such as those supported by tools including flow charts, Labview programming and Lego construction. In this study, activity theory was used as an analytic tool to examine the social construction of meaning. There was a focus on the effect of teachers’ goals and the rules they enacted upon student use of the flow chart planning tool, and the tools of the programming language Labview and Lego construction. It was found that the articulation of a teacher’s goals via rules and divisions of labour helped to form distinct communities of learning and influenced the development of different problem solving strategies. The use of the planning tool flow charting was associated with continuity of approach, integration of problem solutions including appreciation of the nexus between construction and programming, and greater educational transformation. Students who flow charted defined problems in a more holistic way and demonstrated more methodical, insightful and integrated approaches to their use of tools. The findings have implications for teaching in design dominated learning environments.

  1. Use of Audible and Chart-recorded Ultrasonography to Monitor Fetal Heart Rate and Uterine Blood Flow Parameters in Cattle

    USDA-ARS?s Scientific Manuscript database

    The objective of the present study was to evaluate the use of audible chart-recorded doppler ultrasonography (DUS) to monitor both uterine blood flow and fetal heart rate (FHR) during pregnancy in dairy cattle. Possible applications of DUS include the monitoring of fetal distress when a pregnancy be...

  2. Using Statistical Process Control to Make Data-Based Clinical Decisions.

    ERIC Educational Resources Information Center

    Pfadt, Al; Wheeler, Donald J.

    1995-01-01

    Statistical process control (SPC), which employs simple statistical tools and problem-solving techniques such as histograms, control charts, flow charts, and Pareto charts to implement continual product improvement procedures, can be incorporated into human service organizations. Examples illustrate use of SPC procedures to analyze behavioral data…

  3. Primary Gastrointestinal Lymphoma

    PubMed Central

    Chen, Yinting; Chen, Yanzhu; Chen, Shaojie; Wu, Lili; Xu, Lishu; Lian, Guoda; Yang, Kege; Li, Yaqing; Zeng, Linjuan; Huang, Kaihong

    2015-01-01

    Abstract Primary gastrointestinal lymphoma (PGIL) is a rare malignant tumor without standard diagnosis and treatment methods. This study is aimed to systematically analyze its clinical characteristics and draw out an appropriate flow chart of diagnosis and treatment process for PGIL in China. This study retrospectively analyzed the clinicopathological characteristics, diagnostic approaches, prognostic factors, and therapeutic modalities in 415 cases of PGIL in Chinese province of Guangdong. A systematic review was conducted in 118 studies containing 5075 patients to further identify clinical manifestations and mortalities of therapeutic modalities. The most common clinical presentations were abdominal pain and bloody stools. Endoscopic biopsy was an important diagnostic means, and usually more than once to make a definite diagnosis. Retrospective multicenter clinical study showed that younger onset age (<60 years), female, one region involved, one lesion, early stage, International Prognostic Index (IPI ≤1), normal lactate dehydrogenase (LDH), normal albumin, and nonemergency operation were significant prognostic factors for B-cell lymphoma; non-B symptom, tumor restricted to gastric or ileocecal region, one lesion, performance status (PS ≤1), normal LDH, and nonsurgery alone were significant prognostic factors for T-cell lymphoma. Site of origin and IPI were independent prognostic factors for B-cell lymphoma; PS was the independent prognostic factor for T-cell lymphoma. And T-cell lymphoma had worse overall survival (OS) and progression-free survival (PFS) than B-cell lymphoma. Among different therapeutic modalities, chemotherapy alone or combined with surgery showed better OS and PFS than surgery alone for diffuse large B-cell lymphoma (DLBCL) of stage I/II E and T-cell lymphoma. For DLBCL of stage III E/IV and mucosa-associated lymphoid tissue lymphoma, OS and PFS did not differ among different therapeutic groups. In meta-analysis, surgery plus chemotherapy showed lowest mortality. Chemotherapy alone or combined with surgery may be the first-line treatment for DLBCL of stage I/II E and T-cell lymphoma. A flow chart of diagnosis and treatment process for PGIL was approximately drew out. PMID:26632732

  4. A Quantitative Methodology for Determining the Critical Benchmarks for Project 2061 Strand Maps

    ERIC Educational Resources Information Center

    Kuhn, G.

    2008-01-01

    The American Association for the Advancement of Science (AAAS) was tasked with identifying the key science concepts for science literacy in K-12 students in America (AAAS, 1990, 1993). The AAAS Atlas of Science Literacy (2001) has organized roughly half of these science concepts or benchmarks into fifty flow charts. Each flow chart or strand map…

  5. Tularosa Basin Play Fairway Analysis: Methodology Flow Charts

    DOE Data Explorer

    Adam Brandt

    2015-11-15

    These images show the comprehensive methodology used for creation of a Play Fairway Analysis to explore the geothermal resource potential of the Tularosa Basin, New Mexico. The deterministic methodology was originated by the petroleum industry, but was custom-modified to function as a knowledge-based geothermal exploration tool. The stochastic PFA flow chart uses weights of evidence, and is data-driven.

  6. 9. Photocopy of command flow chart of NIKE Battalion, Headquarters ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    9. Photocopy of command flow chart of NIKE Battalion, Headquarters Battery and Missile Battery from Procedures and Drills for NIKE Ajax System, Department of the Army Field Manual, FM-44-80 from Institute for Military History, Carlisle Barracks, Carlisle, PA 1956 - NIKE Missile Battery PR-79, East Windsor Road south of State Route 101, Foster, Providence County, RI

  7. Development of a weight/sizing design synthesis computer program. Volume 2: Program Description

    NASA Technical Reports Server (NTRS)

    Garrison, J. M.

    1973-01-01

    The program for the computerized analysis of weight estimation relationships for those elements of the space shuttle vehicle which contribute a significant portion of the inert weight is discussed. A listing of each module and subroutine of the program is presented. Included are a generalized flow chart describing the subroutine linkage of the complete program and detailed flow charts for each subprogram.

  8. Application of machine learning and expert systems to Statistical Process Control (SPC) chart interpretation

    NASA Technical Reports Server (NTRS)

    Shewhart, Mark

    1991-01-01

    Statistical Process Control (SPC) charts are one of several tools used in quality control. Other tools include flow charts, histograms, cause and effect diagrams, check sheets, Pareto diagrams, graphs, and scatter diagrams. A control chart is simply a graph which indicates process variation over time. The purpose of drawing a control chart is to detect any changes in the process signalled by abnormal points or patterns on the graph. The Artificial Intelligence Support Center (AISC) of the Acquisition Logistics Division has developed a hybrid machine learning expert system prototype which automates the process of constructing and interpreting control charts.

  9. Evaluation of audit-based performance measures for dental care plans.

    PubMed

    Bader, J D; Shugars, D A; White, B A; Rindal, D B

    1999-01-01

    Although a set of clinical performance measures, i.e., a report card for dental plans, has been designed for use with administrative data, most plans do not have administrative data systems containing the data needed to calculate the measures. Therefore, we evaluated the use of a set of proxy clinical performance measures calculated from data obtained through chart audits. Chart audits were conducted in seven dental programs--three public health clinics, two dental health maintenance organizations (DHMO), and two preferred provider organizations (PPO). In all instances audits were completed by clinical staff who had been trained using telephone consultation and a self-instructional audit manual. The performance measures were calculated for the seven programs, audit reliability was assessed in four programs, and for one program the audit-based proxy measures were compared to the measures calculated using administrative data. The audit-based measures were sensitive to known differences in program performance. The chart audit procedures yielded reasonably reliable data. However, missing data in patient charts rendered the calculation of some measures problematic--namely, caries and periodontal disease assessment and experience. Agreement between administrative and audit-based measures was good for most, but not all, measures in one program. The audit-based proxy measures represent a complex but feasible approach to the calculation of performance measures for those programs lacking robust administrative data systems. However, until charts contain more complete diagnostic information (i.e., periodontal charting and diagnostic codes or reason-for-treatment codes), accurate determination of these aspects of clinical performance will be difficult.

  10. Analyzing Vehicle Operator Deviations

    DTIC Science & Technology

    2008-07-01

    Organization Report No. Scarborough A, Bailey L, Pounds J 9. Performing Organization Name and Address 10. Work Unit No. ( TRAIS ) FAA Civil...Investigation Reporting Form Instructions Use the accompanying flow charts (D4-D14) and Data Reporting Form (D15-D18) to document the results of the...happened, use the Entry Level Flow Chart (D3) to identify the relevant mental processes that were involved in the VOD. For each mental process identified

  11. System Study at SUNY College Bookstore/Oswego

    ERIC Educational Resources Information Center

    DeVita, Richard; And Others

    1975-01-01

    A system study of the textbook ordering department is presented including systems flow chart, chart of activities, and description of operations and procedures for utilizing the computer system. Changes based on the study are noted. (JT)

  12. Performance Charts for the Turbojet Engine

    NASA Technical Reports Server (NTRS)

    Pinkel, Benjamin; Karp, Irving M.

    1947-01-01

    Charts are presented for computing the thrust, fuel consumption, and other performance values of a turbojet engine for any given set of operating conditions and component efficiencies. The effects of the pressure losses in the inlet duct and combustion chamber, the variation in the physical properties of the gas as it passes through the cycle, and the change in mass flow by the addition of fuel are included. The principle performance charts show the effects of the primary variables and correction charts provide the effects of the secondary variables.

  13. Toward a New Brewing Control Chart for the 21st Century.

    PubMed

    Melrose, John; Roman-Corrochano, Borja; Montoya-Guerra, Marcela; Bakalis, Serafim

    2018-04-23

    This paper describes new results from a base model of brewing from a bed of packed coffee grains. The model solves for the diffusion of soluble species out of a distribution of particles into the flow through the bed pore space. It requires a limited set of input parameters. It gives a simple picture of the basic physics of coffee brewing and sets out a set of reduced variables for this process. The importance of bed extraction efficiency is elucidated. A coffee brewing control chart has been widely used to describe the region of ideal coffee brewing for some 50 years. A new chart is needed, however, one that connects actual brewing conditions (weight, flow rate, brew time, grind, etc.) to the yield and strength of brews. The paper shows a new approach to brewing control charts, including brew time and bed extraction efficiency as control parameters. Using the base model, an example chart will be given for a particular grind ratio of coarse to fine particles, and an "espresso regime" will be picked out. From such a chart yield, volume and strength of a brew can be read off at will.

  14. Validation of Living Donor Nephrectomy Codes

    PubMed Central

    Lam, Ngan N.; Lentine, Krista L.; Klarenbach, Scott; Sood, Manish M.; Kuwornu, Paul J.; Naylor, Kyla L.; Knoll, Gregory A.; Kim, S. Joseph; Young, Ann; Garg, Amit X.

    2018-01-01

    Background: Use of administrative data for outcomes assessment in living kidney donors is increasing given the rarity of complications and challenges with loss to follow-up. Objective: To assess the validity of living donor nephrectomy in health care administrative databases compared with the reference standard of manual chart review. Design: Retrospective cohort study. Setting: 5 major transplant centers in Ontario, Canada. Patients: Living kidney donors between 2003 and 2010. Measurements: Sensitivity and positive predictive value (PPV). Methods: Using administrative databases, we conducted a retrospective study to determine the validity of diagnostic and procedural codes for living donor nephrectomies. The reference standard was living donor nephrectomies identified through the province’s tissue and organ procurement agency, with verification by manual chart review. Operating characteristics (sensitivity and PPV) of various algorithms using diagnostic, procedural, and physician billing codes were calculated. Results: During the study period, there were a total of 1199 living donor nephrectomies. Overall, the best algorithm for identifying living kidney donors was the presence of 1 diagnostic code for kidney donor (ICD-10 Z52.4) and 1 procedural code for kidney procurement/excision (1PC58, 1PC89, 1PC91). Compared with the reference standard, this algorithm had a sensitivity of 97% and a PPV of 90%. The diagnostic and procedural codes performed better than the physician billing codes (sensitivity 60%, PPV 78%). Limitations: The donor chart review and validation study was performed in Ontario and may not be generalizable to other regions. Conclusions: An algorithm consisting of 1 diagnostic and 1 procedural code can be reliably used to conduct health services research that requires the accurate determination of living kidney donors at the population level. PMID:29662679

  15. The convergence of personality disorder diagnoses across different methods among monolingual (Spanish-speaking only) Hispanic patients in substance use treatment.

    PubMed

    Samuel, Douglas B; Añez, Luis M; Paris, Manuel; Grilo, Carlos M

    2014-04-01

    Methods for diagnosing personality disorders (PDs) within clinical settings typically diverge from those used in treatment research. Treatment groups in research studies are routinely diagnosed using semistructured interviews or self-report questionnaires, yet these methods show poor agreement with clinical diagnoses recorded in medical charts or assigned by treating clinicians, reducing the potential for evidence-based practice. Furthermore, existing research has been limited by focusing on primarily White and English-speaking participants. Our study extended prior research by comparing 4 independent methods of PD diagnosis, including self-report questionnaire, semistructured interview, chart diagnoses, and ratings by treating clinicians, within a clinical series of 130 monolingual (Spanish only) Hispanic persons (69% male; M age 37.4), in treatment for substance use. The authors examined the convergence of the Diagnostic and Statistical Manual of Mental Disorders (4th ed.; DSM-IV) PD diagnoses across these methods. PD diagnoses appeared infrequently within medical charts but were diagnosed at higher levels by independent treating clinicians, self-report questionnaires, and semistructured interviews. Nonetheless, diagnostic concordance between clinical diagnoses and the other methods were poor (κ < .20). Convergence of PD diagnoses across diagnostic methods for Spanish-speaking Hispanic persons are comparable to other groups allaying concerns about cross-cultural application of PD diagnoses. Additionally, the results of this study echo previous research in suggesting that clinicians' PD diagnoses overlap little with self-report questionnaires or semistructured diagnostic interviews and suggest that PDs are underdiagnosed using standard diagnostic approaches. Implications for the clinical application of empirically supported research are discussed. PsycINFO Database Record (c) 2014 APA, all rights reserved

  16. Alternative diagnosis in the putative ventilator-associated pneumonia patient not meeting lavage-based diagnostic criteria.

    PubMed

    Schoemakers, Rik J; Schnabel, Ronny; Oudhuis, Guy J; Linssen, Catharina F M; van Mook, Walther N K A; Verbon, Annelies; Bergmans, Dennis C J J

    2014-12-01

    The clinical picture of ventilator-associated pneumonia (VAP) can be mimicked by other infectious and non-infectious diseases. The aim of this study was to determine the alternative diagnoses and to develop a diagnostic flow chart for patients suspected of having VAP not meeting the diagnostic broncho-alveolar lavage (BAL) criteria. Adult intensive care patients with a clinical suspicion of VAP and negative BAL results were included. The clinical suspicion of VAP was based on the combination of clinical, radiological, and microbiological criteria. BAL was considered positive if cell differentiation revealed ≥ 2% cells with intracellular organisms and/or quantitative culture results of ≥ 10(4) cfu/ml. The most likely alternative diagnosis of fever and pulmonary densities was retrospectively determined by two authors independently. In all, 110 of 207 patients with suspected VAP did not meet the diagnostic BAL criteria and required further diagnostic evaluation. In 67 patients an alternative diagnosis for fever could be found. In 51 patients an alternative diagnosis of both fever and pulmonary densities could be established. In almost 40% of patients no alternative diagnosis could be provided. Non-bacterial pneumonia was diagnosed in 10 patients with Herpes simplex virus 1 (HSV-1) as the most common pathogen. In eight patients non-infectious pneumonitis was diagnosed. Due to the wide range of alternative diagnoses and applied tests the diagnostic work-up proved to be necessarily individualized and guided by repeated clinical assessment. The most frequently found alternative diagnoses were viral pneumonia and non-infectious pneumonitis.

  17. An Approach for Implementing a Microcomputer Based Report Origination System in the Ada Programming Language

    DTIC Science & Technology

    1983-03-01

    Decision Tree -------------------- 62 4-E. PACKAGE unitrep Action/Area Selection flow Chart 82 4-7. PACKAGE unitrep Control Flow Chart...the originetor wculd manually draft simple, readable, formatted iressages using "-i predef.ined forms and decision logic trees . This alternative was...Study Analysis DATA CCNTENT ERRORS PERCENT OF ERRORS Character Type 2.1 Calcvlations/Associations 14.3 Message Identification 4.? Value Pisiratch 22.E

  18. A Thermodynamic Study of the Turbojet Engine

    NASA Technical Reports Server (NTRS)

    Pinkel, Benjamin; Karp, Irvin M

    1947-01-01

    Charts are presented for computing thrust, fuel consumption, and other performance values of a turbojet engine for any given set of operating conditions and component efficiencies. The effects of pressure losses in the inlet duct and the combustion chamber, of variation in physical properties of the gas as it passes through the system, of reheating of the gas due to turbine losses, and of change in mass flow by the addition of fuel are included. The principle performance chart shows the effects of primary variables and correction charts provide the effects of secondary variables and of turbine-loss reheat on the performance of the system. The influence of characteristics of a given compressor and turbine on performance of a turbojet engine containing a matched set of these given components is discussed for cases of an engine with a centrifugal-flow compressor and of an engine with an axial-flow compressor.

  19. Program and charts for determining shock tube, and expansion tunnel flow quantities for real air

    NASA Technical Reports Server (NTRS)

    Miller, C. G., III; Wilder, S. E.

    1975-01-01

    A computer program in FORTRAN 4 language was written to determine shock tube, expansion tube, and expansion tunnel flow quantities for real-air test gas. This program permits, as input data, a number of possible combinations of flow quantities generally measured during a test. The versatility of the program is enhanced by the inclusion of such effects as a standing or totally reflected shock at the secondary diaphragm, thermochemical-equilibrium flow expansion and frozen flow expansion for the expansion tube and expansion tunnel, attenuation of the flow in traversing the acceleration section of the expansion tube, real air as the acceleration gas, and the effect of wall boundary layer on the acceleration section air flow. Charts which provide a rapid estimation of expansion tube performance prior to a test are included.

  20. Design of Customizable Automated Low Cost Eye Testing System

    PubMed Central

    K, Ganesan; D, Shalini

    2014-01-01

    Background and Objectives: In many underdeveloped and third world countries, eye care is often neglected due to illiteracy. Particularly people in rural areas suffer with eye problems due to mal nutrition. The government is spending lot of money and efforts in screening the people at periodic intervals. One of the challenges faced by the doctors is screening the school children. Materials and Methods: The standard Snellen letter chart based diagnostic system does not work always. There are instances where the first few students who undergo this diagnostic system, memorize the letter sequence of the Snellen letter chart and convey the same to other fellow students. Hence other students simply read out the Snellen letter sequence from their memory, not by looking at the Snellen letter chart. Thus there is a need of randomizing the sequence of letters being displayed on the Snellen letter chart for every student to be diagnosed for eye testing. Conclusion: In the present paper we are proposing a customizable, software based, cost effective solution which involves a standard personal computer (PC) fitted with a camera, headphone and speaker system. The envisaged system can be administered even by the trained persons. The proposed system is also suitable for remote diagnosis of patients, particularly in the field of telemedicine. PMID:24783089

  1. Performance Charts for a Turbojet System

    NASA Technical Reports Server (NTRS)

    Karp, Irving M.

    1947-01-01

    Convenient charts are presented for computing the thrust, fuel consumption, and other performance values of a turbojet system. These charts take into account the effects of ram pressure, compressor pressure ratio, ratio of combustion-chamber-outlet temperature to atmospheric temperature, compressor efficiency, turbine efficiency, combustion efficiency, discharge-nozzle coefficient, losses in total pressure in the inlet to the jet-propulsion unit and in the combustion chamber, and variation in specific heats with temperature. The principal performance charts show clearly the effects of the primary variables and correction charts provide the effects of the secondary variables. The performance of illustrative cases of turbojet systems is given. It is shown that maximum thrust per unit mass rate of air flow occurs at a lower compressor pressure ratio than minimum specific fuel consumption. The thrust per unit mass rate of air flow increases as the combustion-chamber discharge temperature increases. For minimum specific fuel consumption, however, an optimum combustion-chamber discharge temperature exists, which in some cases may be less than the limiting temperature imposed by the strength temperature characteristics of present materials.

  2. Coding and Flow Charting as Applied to UICSM Programed Texts (1962-1963 Versions). Comparative Studies of Principles for Programming Mathematics in Automated Instruction. Technical Report.

    ERIC Educational Resources Information Center

    Stolurow, Lawrence M.; And Others

    Coding systems need to be developed to account for computer decisions on every frame of a self-instructional program. In flow charts of the UICSM high school math programed series, each frame or page is represented by a diagramatic convention: diamond if a mainline frame, a rectangle if a quiz frame, a bottom-heavy trapezoid if a review or…

  3. The study of insect blood-feeding behaviour. 2. Recording techniques and the use of flow charts.

    PubMed

    Smith, J J; Friend, W G

    1987-01-01

    This paper continues a discussion of approaches and methodologies we have used in our studies of feeding in haematophagous insects. Described are techniques for directly monitoring behaviour: electrical recording of feeding behaviour via resistance changes in the food canal, optical methods for monitoring mouthpart activity, and a computer technique for behavioural event recording. Also described is the use of "flow charts" or "decision diagrams" to model interrelated sequences of behaviours.

  4. Evaluation of Shiryaev-Roberts procedure for on-line environmental radiation monitoring.

    PubMed

    Watson, Mara M; Seliman, Ayman F; Bliznyuk, Valery N; DeVol, Timothy A

    2018-04-30

    Water can become contaminated as a result of a leak from a nuclear facility, such as a waste facility, or from clandestine nuclear activity. Low-level on-line radiation monitoring is needed to detect these events in real time. A Bayesian control chart method, Shiryaev-Roberts (SR) procedure, was compared with classical methods, 3-σ and cumulative sum (CUSUM), for quantifying an accumulating signal from an extractive scintillating resin flow-cell detection system. Solutions containing 0.10-5.0 Bq/L of 99 Tc, as T99cO 4 - were pumped through a flow cell packed with extractive scintillating resin used in conjunction with a Beta-RAM Model 5 HPLC detector. While T99cO 4 - accumulated on the resin, time series data were collected. Control chart methods were applied to the data using statistical algorithms developed in MATLAB. SR charts were constructed using Poisson (Poisson SR) and Gaussian (Gaussian SR) probability distributions of count data to estimate the likelihood ratio. Poisson and Gaussian SR charts required less volume of radioactive solution at a fixed concentration to exceed the control limit in most cases than 3-σ and CUSUM control charts, particularly solutions with lower activity. SR is thus the ideal control chart for low-level on-line radiation monitoring. Once the control limit was exceeded, activity concentrations were estimated from the SR control chart using the control chart slope on a semi-logarithmic plot. A linear regression fit was applied to averaged slope data for five activity concentration groupings for Poisson and Gaussian SR control charts. A correlation coefficient (R 2 ) of 0.77 for Poisson SR and 0.90 for Gaussian SR suggest this method will adequately estimate activity concentration for an unknown solution. Copyright © 2018 Elsevier Ltd. All rights reserved.

  5. Visualizing human communication in business process simulations

    NASA Astrophysics Data System (ADS)

    Groehn, Matti; Jalkanen, Janne; Haho, Paeivi; Nieminen, Marko; Smeds, Riitta

    1999-03-01

    In this paper a description of business process simulation is given. Crucial part in the simulation of business processes is the analysis of social contacts between the participants. We will introduce a tool to collect log data and how this log data can be effectively analyzed using two different kind of methods: discussion flow charts and self-organizing maps. Discussion flow charts revealed the communication patterns and self-organizing maps are a very effective way of clustering the participants into development groups.

  6. THE DIFFERENTIAL DIAGNOSIS OF NON-SPECIFIC PARAESTHESIA ABOUT THE WRIST OR HAND USING A FLOW CHART

    PubMed Central

    Reggars, John W.

    1993-01-01

    A common clinical presentation in the Chiropractor's office is that of vague and unilateral paraesthesia of the wrist or hand. Often the patient is unable to identify any definite dermatomal pattern and in such cases an accurate diagnosis becomes somewhat difficult. The following paper, incorporating a flow chart, provides the clinician with a logical sequence for the clinical exam in an attempt to arrive at the correct diagnosis, particularly those with mechanical causes. PMID:17989743

  7. Twenty-Four-Hour Voiding Diaries Versus 3-Day Voiding Diaries: A Clinical Comparison.

    PubMed

    Elmer, Caroline; Murphy, Amber; Elliott, John O; Book, Nicole M

    This study aimed to determine if 24-hour versus 3-day voiding diary affects medical decision making for women with urinary incontinence. A retrospective chart review was conducted of patients presenting to the OhioHealth Urogynecology Physician group for urinary incontinence from 2009 to 2011. Practice protocol includes patient completion of a 3-day voiding diary before their appointment. Diagnostic and treatment plans were extracted based on the initial patient encounter and 3-day voiding diary. A chart review was then completed with the first 24 hours of the same diaries, principal history, and physical examination data compiled into a separate chart. These charts were then reevaluated by the same physician who initially provided care to the patient but were blinded to their previous orders, impressions, and plans. New plans were then created based on the 24-hour diaries and compared with the original plans. One hundred eighty-six charts were reviewed. There was good agreement between 24-hour and 3-day diaries in recommendations for first-line behavioral modifications (Κ > 0.6) and moderate agreement between diaries in initiation of medical therapy or trial of incontinence pessary (Κ > 0.4). However, 24-hour diaries resulted in a statistically significant increase in invasive diagnostic tests (P < 0.019) and other treatment recommendations when compared with 3-day diaries. Use of 24-hour diaries may result in increased testing when compared with 3-day diaries. It may be prudent to postpone invasive testing in those patients who initially are noncompliant with a longer diary until a more complete history can be obtained.

  8. The Deming Method: Systems Theory for Educational Technology Services.

    ERIC Educational Resources Information Center

    Richie, Mark L.

    1993-01-01

    Discusses quality management principles as taught by W. Edwards Deming and describes their applications to educational technology services. Traditional organizational charts are explained; and benefits of using flow charts in Deming's systems are described, including better communications between departments, building teamwork, and opportunities…

  9. Teaching Electricity.

    ERIC Educational Resources Information Center

    Iona, Mario

    1982-01-01

    To clarify the meaning of electrical terms, a chart is used to compare electrical concepts and relationships with a more easily visualized system in which water flows from a hilltop reservoir through a pipe to drive a mill at the bottom of the hill. A diagram accompanies the chart. (Author/SK)

  10. Wisconsin Recertification Manual for Public Librarians.

    ERIC Educational Resources Information Center

    Fox, Robert; And Others

    Designed to assist public librarians certified after May 1, 1979, this manual explains Wisconsin recertification requirements based on continuing education. It provides continuing education guidelines, a flow chart of the recertification process, an individual learning activity form, an annual report form, a conversion chart for assignment of…

  11. Structured Analysis and the Data Flow Diagram: Tools for Library Analysis.

    ERIC Educational Resources Information Center

    Carlson, David H.

    1986-01-01

    This article discusses tools developed to aid the systems analysis process (program evaluation and review technique, Gantt charts, organizational charts, decision tables, flowcharts, hierarchy plus input-process-output). Similarities and differences among techniques, library applications of analysis, structured systems analysis, and the data flow…

  12. Binding blocks: building the Universe one nucleus at a time

    NASA Astrophysics Data System (ADS)

    Diget, C. Aa; Pastore, A.; Leech, K.; Haylett, T.; Lock, S.; Sanders, T.; Shelley, M.; Willett, H. V.; Keegans, J.; Sinclair, L.; Simpson, E. C.; Binding Blocks Collaboration

    2017-03-01

    We present a new teaching and outreach activity based around the construction of a three-dimensional chart of isotopes using \\text{LEG}{{\\text{O}}\\circledR} bricks5. The activity, binding blocks, demonstrates nuclear and astrophysical processes through a seven-meter chart of all nuclear isotopes, built from over 26 000 \\text{LEG}{{\\text{O}}\\circledR} bricks. It integrates A-Level and GCSE curricula across areas of nuclear physics, astrophysics, and chemistry, including: nuclear decays (through the colours in the chart); nuclear binding energy (through tower heights); production of chemical elements in the cosmos; fusion processes in stars and fusion energy on Earth; as well as links to medical physics, particularly diagnostics and radiotherapy.

  13. ANMCO/GICR-IACPR/SICI-GISE Consensus Document: the clinical management of chronic ischaemic cardiomyopathy

    PubMed Central

    Gulizia, Michele Massimo; Colivicchi, Furio; Di Lenarda, Andrea; Musumeci, Giuseppe; Faggiano, Pompilio Massimo; Abrignani, Maurizio Giuseppe; Rossini, Roberta; Fattirolli, Francesco; Valente, Serafina; Mureddu, Gian Francesco; Temporelli, Pier Luigi; Olivari, Zoran; Amico, Antonio Francesco; Casolo, Giancarlo; Fresco, Claudio; Menozzi, Alberto; Nardi, Federico

    2017-01-01

    Stable coronary artery disease (CAD) is a clinical entity of great epidemiological importance. It is becoming increasingly common due to the longer life expectancy, being strictly related to age and to advances in diagnostic techniques and pharmacological and non-pharmacological interventions. Stable CAD encompasses a variety of clinical and anatomic presentations, making the identification of its clinical and anatomical features challenging. Therapeutic interventions should be defined on an individual basis according to the patient’s risk profile. To this aim, management flow charts have been reviewed based on sustainability and appropriateness derived from recent evidence. Special emphasis has been placed on non-pharmacological interventions, stressing the importance of lifestyle changes, including smoking cessation, regular physical activity, and diet. Adherence to therapy as an emerging risk factor is also discussed. PMID:28533729

  14. Best practice guidelines for molecular genetic diagnosis of cystic fibrosis and CFTR-related disorders--updated European recommendations.

    PubMed

    Dequeker, Els; Stuhrmann, Manfred; Morris, Michael A; Casals, Teresa; Castellani, Carlo; Claustres, Mireille; Cuppens, Harry; des Georges, Marie; Ferec, Claude; Macek, Milan; Pignatti, Pier-Franco; Scheffer, Hans; Schwartz, Marianne; Witt, Michal; Schwarz, Martin; Girodon, Emmanuelle

    2009-01-01

    The increasing number of laboratories offering molecular genetic analysis of the CFTR gene and the growing use of commercial kits strengthen the need for an update of previous best practice guidelines (published in 2000). The importance of organizing regional or national laboratory networks, to provide both primary and comprehensive CFTR mutation screening, is stressed. Current guidelines focus on strategies for dealing with increasingly complex situations of CFTR testing. Diagnostic flow charts now include testing in CFTR-related disorders and in fetal bowel anomalies. Emphasis is also placed on the need to consider ethnic or geographic origins of patients and individuals, on basic principles of risk calculation and on the importance of providing accurate laboratory reports. Finally, classification of CFTR mutations is reviewed, with regard to their relevance to pathogenicity and to genetic counselling.

  15. Helicopter rotor wake geometry and its influence in forward flight. Volume 2: Wake geometry charts

    NASA Technical Reports Server (NTRS)

    Egolf, T. A.; Landgrebe, A. J.

    1983-01-01

    Isometric and projection view plots, inflow ratio nomographs, undistorted axial displacement nomographs, undistorted longitudinal and lateral coordinates, generalized axial distortion nomographs, blade/vortex passage charts, blade/vortex intersection angle nomographs, and fore and aft wake boundary charts are discussed. Example condition, in flow ratio, undistorted axial location, longitudinal and lateral coordinates, axial coordinates distortions, blade/tip vortex intersections, angle of intersection, and fore and aft wake boundaries are also discussed.

  16. Syntax Flowcharts for Advanced French Courses.

    ERIC Educational Resources Information Center

    Bryant, William H.

    1983-01-01

    The use of syntax flow charts as a graphic illustration of syntactic rules is suggested as both an instructional and a heuristic tool. Charts for these French structures are presented: negating of verbal expressions; balancing of conditional tenses; use of imperfect versus compound; agreement of past participles; and subjunctive sequences. (MSE)

  17. Estimated Water Flows in 2005: United States

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Smith, C A; Belles, R D; Simon, A J

    2011-03-16

    Flow charts depicting water use in the United States have been constructed from publicly available data and estimates of water use patterns. Approximately 410,500 million gallons per day of water are managed throughout the United States for use in farming, power production, residential, commercial, and industrial applications. Water is obtained from four major resource classes: fresh surface-water, saline (ocean) surface-water, fresh groundwater and saline (brackish) groundwater. Water that is not consumed or evaporated during its use is returned to surface bodies of water. The flow patterns are represented in a compact 'visual atlas' of 52 state-level (all 50 states inmore » addition to Puerto Rico and the Virgin Islands) and one national water flow chart representing a comprehensive systems view of national water resources, use, and disposition.« less

  18. Getting With It: Flow Diagrams

    ERIC Educational Resources Information Center

    Ritchie, W. A.

    1975-01-01

    The use of flow charts in the teaching of college mathematics enhances students' understanding of mathematical processes. Used appropriately in elementary and secondary schools they could also nurture understanding of algorithms. (SD)

  19. Programmers manual for static and dynamic reusable surface insulation stresses (resist)

    NASA Technical Reports Server (NTRS)

    Ogilvie, P. L.; Levy, A.; Austin, F.; Ojalvo, I. U.

    1974-01-01

    Programming information for the RESIST program for the dynamic and thermal stress analysis of the space shuttle surface insulation is presented. The overall flow chart of the program, overlay chart, data set allocation, and subprogram calling sequence are given along with a brief description of the individual subprograms and typical subprogram output.

  20. Tables for the Rapid Estimation of Downwash and Sidewash Behind Wings Performing Various Motions at Supersonic Speeds

    NASA Technical Reports Server (NTRS)

    Bobbitt, Percy J.

    1959-01-01

    Equations for the downwash and sidewash due to supersonic yawed and unswept horseshoe vortices have been utilized in formulating tables and charts to permit a rapid estimation of the flow velocities behind wings performing various steady motions. Tabulations are presented of the downwash and sidewash in the wing vertical plane of symmetry due to a unit-strength yawed horseshoe vortex located at 20 equally spaced spanwise positions along lifting lines of various sweeps. (The bound portion of the yawed vortex is coincident with the lifting line.) Charts are presented for the purpose of estimating the spanwise variations of the flow-field velocities and give longitudinal variations of the downwash and sidewash at a nuMber of vertical and spanwise locations due to a unit-strength unswept horseshoe vortex. Use of the tables and charts to calculate wing downwash or sidewash requires a knowledge of the wing spanwise distribution of circulation. Sample computations for the rolling sidewash and angle-of-attack downwash behind a typical swept wing are presented to demonstrate the use of the tables and charts.

  1. Using Flow Charts to Visualize the Decision-Making Process in Space Weather Forecasting

    NASA Astrophysics Data System (ADS)

    Aung, M. T. Y.; Myat, T.; Zheng, Y.; Mays, M. L.; Ngwira, C.; Damas, M. C.

    2016-12-01

    Our society today relies heavily on technological systems such as satellites, navigation systems, power grids and aviation. These systems are very sensitive to space weather disturbances. When Earth-directed space weather driven by the Sun arrives at the Earth, it causes changes to the Earth's radiation environment and the magnetosphere. Strong disturbances in the magnetosphere of the Earth are responsible for geomagnetic storms that can last from hours to days depending on strength of storms. Geomagnetic storms can severely impact critical infrastructure on Earth, such as the electric power grid, and Solar Energetic Particles that can endanger life in outer space. How can we lessen these adverse effects? They can be lessened through the early warning signals sent by space weather forecasters before CME or high-speed stream arrives. A space weather forecaster's duty is to send predicted notifications to high-tech industries and NASA missions so that they could take extra measures for protection. NASA space weather forecasters make prediction decisions by following certain steps and processes from the time an event occurs at the sun all the way to the impact locations. However, there has never been a tool that helps these forecasters visualize the decision process until now. A flow chart is created to help forecasters visualize the decision process. This flow chart provides basic knowledge of space weather and can be used to train future space weather forecasters. It also helps to cut down the training period and increase consistency in forecasting. The flow chart is also a great reference for people who are already familiar with space weather.

  2. Prenatal Genetic Testing Chart

    MedlinePlus

    ... www.acog.org/Patients/FAQs/Prenatal-Genetic-Diagnostic-Tests › › Resources & Publications Committee Opinions Practice Bulletins Patient Education Green Journal Clinical Updates Practice Management Coding Health Info Technology Professional Liability Managing Your Practice Patient Safety & Quality ...

  3. [Oral contraception].

    PubMed

    Montloin, A

    1990-11-01

    This brief discussion of the different types of oral contraceptives (OCs) makes abundant use of flow charts, tables, and diagrams to present information and stress specific points. The work begins by defining the different hypothalamic, pituitary, and ovarian hormones and diagramming and describing the menstrual cycle. A discussion of combined OCs defines and diagrams monophasic, biphasic, and triphasic pills, distinguishes between different dose levels, and describes the mechanisms of action of OCs. Sequential pills and their mechanism of action are briefly discussed. The discussion of OCs containing progestins distinguishes between low does pills and high dose pills and describes the use of injectable progestins. A table then lists the dose-dependent side effects of estrogens and progestins. Simple instructions are provided for administering pills beginning on the 1st cycle day and for actions to take in the event a pill is forgotten. A flow chart taking into account age and presence or absence of vascular and gynecologic risk factors indicates which type of OC should be selected. Some advantages of OCs are identified, including maximum effectiveness and prevention of benign breast disease and perhaps of some type of rheumatoid arthritis. Another flow chart, on patient monitoring, identifies the contraindications that should be ruled out before OCs are prescribed and the routine follow-up examinations required for safe use. Other charts list absolute and relative contraindications and possible drug interferences.

  4. Dealing with the Surgical and Medical Challenges of Penetrating Brain Injuries

    PubMed Central

    Syrmos, Nikolaos; Ganau, Mario; De Carlo, Antonella; Prisco, Lara; Ganau, Laura; Valadakis, Vasileios; Grigoriou, Kostantinos; Iliadis, Charalampos; Arvanitakis, Dimitrios

    2013-01-01

    Peacetime has reduced the overall incidence of penetrating brain injuries (PBI), and those related to missile penetration are not common anymore at least in western countries. Nevertheless, PBI still occur, and car crashes or work accidents are their main causes. The management of such cases is characterized by many challenges, not only from a surgical and medical point of view, but also for the different and sometimes bizarre dynamics by which they present. Herein we report an unusual deep penetrating brain injury, due to a high-energy crash against a metallic rod in a construction site, with a good surgical outcome despite dramatic clinical conditions on admission. A discussion of the surgical results and functional outcome related to PBI, as found in the English medical literature, is provided. Moreover the most common postoperative complications along with the diagnostic flow charts and therapeutic options useful to prevent inappropriate treatment are highlighted. PMID:23365777

  5. Banning PRF programmer's manual. [considering MOS integrated circuits

    NASA Technical Reports Server (NTRS)

    Kuelthau, R. L.

    1970-01-01

    This manual describes a modification of the Banning placement routing folding program. The modifications to this program have been made to implement it on a Sigma 5 computer. Flow charts of various levels, beginning with high level functional diagrams and working down to the level of detail deemed necessary to understand the operations of the various sections of the program are included. Along with the flow charts of each subroutine is a narrative description of its functional operation and definitions of its arrays and key variables, and a section to assist the programmer in dimensioning the program's arrays.

  6. HAL/SM system functional design specification. [systems analysis and design analysis of central processing units

    NASA Technical Reports Server (NTRS)

    Ross, C.; Williams, G. P. W., Jr.

    1975-01-01

    The functional design of a preprocessor, and subsystems is described. A structure chart and a data flow diagram are included for each subsystem. Also a group of intermodule interface definitions (one definition per module) is included immediately following the structure chart and data flow for a particular subsystem. Each of these intermodule interface definitions consists of the identification of the module, the function the module is to perform, the identification and definition of parameter interfaces to the module, and any design notes associated with the module. Also described are compilers and computer libraries.

  7. How well do commonly used data presentation formats support comparative effectiveness evaluations?

    PubMed Central

    Dolan, James G.; Qian, Feng; Veazie, Peter J.

    2012-01-01

    Background Good decisions depend on an accurate understanding of the comparative effectiveness of decision alternatives. The best way convey data needed to support these comparisons is unknown. Objective To determine how well five commonly used data presentation formats convey comparative effectiveness information. Design Internet survey using a factorial design. Subjects 279 members of an online survey panel. Intervention Study participants compared outcomes associated with three hypothetical screening test options relative to five possible outcomes with probabilities ranging from 2 per 5,000 (0.04%) to 500 per 1,000 (50%). Data presentation formats included a table, a “magnified” bar chart, a risk scale, a frequency diagram, and an icon array. Measurements Outcomes included the number of correct ordinal judgments regarding the more likely of two outcomes, the ratio of perceived versus actual relative likelihoods of the paired outcomes, the inter-subject consistency of responses, and perceived clarity. Results The mean number of correct ordinal judgments was 12 of 15 (80%), with no differences among data formats. On average, there was a 3.3-fold difference between perceived and actual likelihood ratios,95%CI: 3.0 to 3.6. Comparative judgments based on flow charts, icon arrays, and tables were all significantly more accurate and consistent than those based on risk scales and bar charts, p < 0.001. The most clearly perceived formats were the table and the flow chart. Low subjective numeracy was associated with less accurate and more variable data interpretations and lower perceived clarity for icon displays, bar charts, and flow diagrams. Conclusions None of the data presentation formats studied can reliably provide patients, especially those with low subjective numeracy, with an accurate understanding of comparative effectiveness information. PMID:22618998

  8. The Two-By-Two Array: An Aid in Conceptualization and Problem Solving

    ERIC Educational Resources Information Center

    Eberhart, James

    2004-01-01

    The fields of mathematics, science, and engineering are replete with diagrams of many varieties. They range in nature from the Venn diagrams of symbolic logic to the Periodic Chart of the Elements; and from the fault trees of risk assessment to the flow charts used to describe laboratory procedures, industrial processes, and computer programs. All…

  9. Towards first principle medical diagnostics: on the importance of disease-disease and sign-sign interactions

    NASA Astrophysics Data System (ADS)

    Ramezanpour, Abolfazl; Mashaghi, Alireza

    2017-07-01

    A fundamental problem in medicine and biology is to assign states, e.g. healthy or diseased, to cells, organs or individuals. State assignment or making a diagnosis is often a nontrivial and challenging process and, with the advent of omics technologies, the diagnostic challenge is becoming more and more serious. The challenge lies not only in the increasing number of measured properties and dynamics of the system (e.g. cell or human body) but also in the co-evolution of multiple states and overlapping properties, and degeneracy of states. We develop, from first principles, a generic rational framework for state assignment in cell biology and medicine, and demonstrate its applicability with a few simple theoretical case studies from medical diagnostics. We show how disease-related statistical information can be used to build a comprehensive model that includes the relevant dependencies between clinical and laboratory findings (signs) and diseases. In particular, we include disease-disease and sign-sign interactions and study how one can infer the probability of a disease in a patient with given signs. We perform comparative analysis with simple benchmark models to check the performances of our models. We find that including interactions can significantly change the statistical importance of the signs and diseases. This first principles approach, as we show, facilitates the early diagnosis of disease by taking interactions into accounts, and enables the construction of consensus diagnostic flow charts. Additionally, we envision that our approach will find applications in systems biology, and in particular, in characterizing the phenome via the metabolome, the proteome, the transcriptome, and the genome.

  10. Small-for-gestational age and large-for-gestational age thresholds to predict infants at risk of adverse delivery and neonatal outcomes: are current charts adequate? An observational study from the Born in Bradford cohort

    PubMed Central

    Norris, T; Johnson, W; Farrar, D; Tuffnell, D; Wright, J; Cameron, N

    2015-01-01

    Objectives Construct an ethnic-specific chart and compare the prediction of adverse outcomes using this chart with the clinically recommended UK-WHO and customised birth weight charts using cut-offs for small-for-gestational age (SGA: birth weight <10th centile) and large-for-gestational age (LGA: birth weight >90th centile). Design Prospective cohort study. Setting Born in Bradford (BiB) study, UK. Participants 3980 White British and 4448 Pakistani infants with complete data for gestational age, birth weight, ethnicity, maternal height, weight and parity. Main outcome measures Prevalence of SGA and LGA, using the three charts and indicators of diagnostic utility (sensitivity, specificity and area under the receiver operating characteristic (AUROC)) of these chart-specific cut-offs to predict delivery and neonatal outcomes and a composite outcome. Results In White British and Pakistani infants, the prevalence of SGA and LGA differed depending on the chart used. Increased risk of SGA was observed when using the UK-WHO and customised charts as opposed to the ethnic-specific chart, while the opposite was apparent when classifying LGA infants. However, the predictive utility of all three charts to identify adverse clinical outcomes was poor, with only the prediction of shoulder dystocia achieving an AUROC>0.62 on all three charts. Conclusions Despite being recommended in national clinical guidelines, the UK-WHO and customised birth weight charts perform poorly at identifying infants at risk of adverse neonatal outcomes. Being small or large may increase the risk of an adverse outcome; however, size alone is not sensitive or specific enough with current detection to be useful. However, a significant amount of missing data for some of the outcomes may have limited the power needed to determine true associations. PMID:25783424

  11. Systematic review of proposed definitions of nocturnal polyuria and population-based evidence of their diagnostic accuracy.

    PubMed

    Olesen, Tine Kold; Denys, Marie-Astrid; Vande Walle, Johan; Everaert, Karel

    2018-02-06

    Background Evidence of diagnostic accuracy for proposed definitions of nocturnal polyuria is currently unclear. Purpose Systematic review to determine population-based evidence of the diagnostic accuracy of proposed definitions of nocturnal polyuria based on data from frequency-volume charts. Methods Seventeen pre-specified search terms identified 351 unique investigations published from 1990 to 2016 in BIOSIS, Embase, Embase Alerts, International Pharmaceutical Abstract, Medline, and Cochrane. Thirteen original communications were included in this review based on pre-specified exclusion criteria. Data were extracted from each paper regarding subject age, sex, ethnicity, health status, sample size, data collection methods, and diagnostic discrimination of proposed definitions including sensitivity, specificity, positive and negative predictive value. Results The sample size of study cohorts, participant age, sex, ethnicity, and health status varied considerably in 13 studies reporting on the diagnostic performance of seven different definitions of nocturnal polyuria using frequency-volume chart data from 4968 participants. Most study cohorts were small, mono-ethnic, including only Caucasian males aged 50 or higher with primary or secondary polyuria that were compared to a control group of healthy men without nocturia in prospective or retrospective settings. Proposed definitions had poor discriminatory accuracy in evaluations based on data from subjects independent from the original study cohorts with findings being similar regarding the most widely evaluated definition endorsed by ICS. Conclusions Diagnostic performance characteristics for proposed definitions of nocturnal polyuria show poor to modest discrimination and are not based on sufficient level of evidence from representative, multi-ethnic population-based data from both females and males of all adult ages.

  12. College Algebra I.

    ERIC Educational Resources Information Center

    Benjamin, Carl; And Others

    Presented are student performance objectives, a student progress chart, and assignment sheets with objective and diagnostic measures for the stated performance objectives in College Algebra I. Topics covered include: sets; vocabulary; linear equations; inequalities; real numbers; operations; factoring; fractions; formulas; ratio, proportion, and…

  13. Automated Methodologies for the Design of Flow Diagrams for Development and Maintenance Activities

    NASA Astrophysics Data System (ADS)

    Shivanand M., Handigund; Shweta, Bhat

    The Software Requirements Specification (SRS) of the organization is a text document prepared by strategic management incorporating the requirements of the organization. These requirements of ongoing business/ project development process involve the software tools, the hardware devices, the manual procedures, the application programs and the communication commands. These components are appropriately ordered for achieving the mission of the concerned process both in the project development and the ongoing business processes, in different flow diagrams viz. activity chart, workflow diagram, activity diagram, component diagram and deployment diagram. This paper proposes two generic, automatic methodologies for the design of various flow diagrams of (i) project development activities, (ii) ongoing business process. The methodologies also resolve the ensuing deadlocks in the flow diagrams and determine the critical paths for the activity chart. Though both methodologies are independent, each complements other in authenticating its correctness and completeness.

  14. Applicability of the 2001 revised diagnostic criteria in Brazilian Vogt-Koyanagi-Harada disease patients.

    PubMed

    Cardoso, Isabel Habeyche; Zajdenweber, Moysés Eduardo; Muccioli, Cristina; Fimamor, Luciana Peixoto; Belfort, Rubens

    2008-01-01

    To determine the applicability of the international revised diagnostic criteria for Vogt-Koyanagi-Harada disease. Retrospective study. Medical charts of 140 patients with the diagnosis of Vogt-Koyanagi-Harada disease, from the Uveitis Sector of the Federal University of Sao Paulo (UNIFESP), were revised and classified following the revised diagnostic criteria. Of the 140 patients, 12.85% fulfilled the criteria for complete disease, 29.28% incomplete disease, 28.57% "probable" Vogt-Koyanagi-Harada disease and 28.27% were considered not Vogt-Koyanagi-Harada disease. The authors consider that the international revised diagnostic criteria have good applicability and are very useful to help in the diagnosis of Vogt-Koyanagi-Harada disease.

  15. Progress of Icelandic Lava Flows Charted by NASA EO-1 Spacecraft

    NASA Image and Video Library

    2014-09-09

    On the night of Sept. 6, 2014 NASA Earth Observing 1 EO-1 spacecraft observed the ongoing eruption at Holuhraun, Iceland. Partially covered by clouds, this scene shows the extent of the lava flows that have been erupting.

  16. Psychiatric Resident and Attending Diagnostic and Prescribing Practices

    ERIC Educational Resources Information Center

    Tripp, Adam C.; Schwartz, Thomas L.

    2008-01-01

    Objective: This study investigates whether two patient population groups, under resident or attending treatment, are equivalent or different in the distribution of patient characteristics, diagnoses, or pharmacotherapy. Methods: Demographic data, psychiatric diagnoses, and pharmacotherapy data were collected for 100 random patient charts of…

  17. MO-A-BRB-03: Integration Issues in Electronic Charting for External Beam Therapy

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sutlief, S.

    2015-06-15

    The process of converting to an electronic chart for radiation therapy can be daunting. It requires a dedicated committee to first research and choose appropriate software, to review the entire documentation policy and flow of the clinic, to convert this system to electronic form or if necessary, redesign the system to more easily conform to the electronic process. Those making the conversion and those who already use electronic charting would benefit from the shared experience of those who have been through the process in the past. Therefore TG262 was convened to provide guidance on electronic charting for external beam radiationmore » therapy and brachytherapy. This course will present the results of an internal survey of task group members on EMR practices in External Beam Radiation Therapy as well as discuss important issues in EMR development and structure for both EBRT and brachytherapy. Learning Objectives: Be familiarized with common practices and pitfalls in development and maintenance of an electronic chart in Radiation Oncology Be familiarized with important issues related to electronic charting in External Beam Radiation Therapy Be familiarized with important issues related to electronic charting in Brachytherapy.« less

  18. MO-A-BRB-02: Considerations and Issues in Electronic Charting for Brachytherapy

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Richardson, S.

    2015-06-15

    The process of converting to an electronic chart for radiation therapy can be daunting. It requires a dedicated committee to first research and choose appropriate software, to review the entire documentation policy and flow of the clinic, to convert this system to electronic form or if necessary, redesign the system to more easily conform to the electronic process. Those making the conversion and those who already use electronic charting would benefit from the shared experience of those who have been through the process in the past. Therefore TG262 was convened to provide guidance on electronic charting for external beam radiationmore » therapy and brachytherapy. This course will present the results of an internal survey of task group members on EMR practices in External Beam Radiation Therapy as well as discuss important issues in EMR development and structure for both EBRT and brachytherapy. Learning Objectives: Be familiarized with common practices and pitfalls in development and maintenance of an electronic chart in Radiation Oncology Be familiarized with important issues related to electronic charting in External Beam Radiation Therapy Be familiarized with important issues related to electronic charting in Brachytherapy.« less

  19. The problem of obesity among adolescents in Hong Kong: a comparison using various diagnostic criteria

    PubMed Central

    Ko, Gary TC; Ozaki, Risa; Wong, Gary WK; Kong, Alice PS; So, Wing-Yee; Tong, Peter CY; Chan, Michael HM; Ho, Chung-Shun; Lam, Christopher WK; Chan, Juliana CN

    2008-01-01

    Background Obesity is now a global epidemic. In this study, we aimed to assess the rates of obesity using several major diagnostic criteria in Chinese school adolescents in Hong Kong. Methods This is a cross-sectional study. Using a computer-generated coding system, we randomly selected schools from different geographical regions in Hong Kong to obtain a representative sample. Subjects aged 11–18 years of age were randomly selected from different class of the schools. Their rates of obesity according to four different international and local criteria were compared [International Obesity Task Force (IOTF) 2000 criterion; the Group of China Obesity Task Force (COTF) 2004 criterion; Centers for Disease Control and Prevention (CDC) 2000 Growth Charts and the Hong Kong Growth Survey (HKGS) charts in 1993]. Results Of the 2098 adolescents [982 (46.8%) boys and 1116 (53.2%) girls], the mean age (± SD) was 15.1 ± 1.8 years (range: 11–18 years; median: 15.0 years). The crude rates of obesity were similar based on IOTF, COTF or CDC criteria (boys: 3.9–6.0%, girls: 1.8–3.7%), however, the rate increased to 11–27% if the HKGS charts were used. Obesity rate varied markedly according to age. It decreased from 8–10% among those aged 12–13 years to 2–4% among those aged 17–18 years. Conclusion The prevalence of obesity in Hong Kong adolescents using various diagnostic criteria were similar except for the 1993 HKGS criteria, which gave an exceeding high figure. Using the IOTF, COTF or CDC criteria, the adolescent obesity in Hong Kong varied from 1.8% to 6.0%. PMID:18315886

  20. A full three dimensional Navier-Stokes numerical simulation of flow field inside a power plant Kaplan turbine using some model test turbine hill chart points

    NASA Astrophysics Data System (ADS)

    Hosseinalipour, S. M.; Raja, A.; Hajikhani, S.

    2012-06-01

    A full three dimensional Navier - Stokes numerical simulation has been performed for performance analysis of a Kaplan turbine which is installed in one of the Irans south dams. No simplifications have been enforced in the simulation. The numerical results have been evaluated using some integral parameters such as the turbine efficiency via comparing the results with existing experimental data from the prototype Hill chart. In part of this study the numerical simulations were performed in order to calculate the prototype turbine efficiencies in some specific points which comes from the scaling up of the model efficiency that are available in the model experimental Hill chart. The results are very promising which shows the good ability of the numerical techniques for resolving the flow characteristics in these kind of complex geometries. A parametric study regarding the evaluation of turbine performance in three different runner angles of the prototype is also performed and the results are cited in this paper.

  1. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mechalakos, J.

    The process of converting to an electronic chart for radiation therapy can be daunting. It requires a dedicated committee to first research and choose appropriate software, to review the entire documentation policy and flow of the clinic, to convert this system to electronic form or if necessary, redesign the system to more easily conform to the electronic process. Those making the conversion and those who already use electronic charting would benefit from the shared experience of those who have been through the process in the past. Therefore TG262 was convened to provide guidance on electronic charting for external beam radiationmore » therapy and brachytherapy. This course will present the results of an internal survey of task group members on EMR practices in External Beam Radiation Therapy as well as discuss important issues in EMR development and structure for both EBRT and brachytherapy. Learning Objectives: Be familiarized with common practices and pitfalls in development and maintenance of an electronic chart in Radiation Oncology Be familiarized with important issues related to electronic charting in External Beam Radiation Therapy Be familiarized with important issues related to electronic charting in Brachytherapy.« less

  2. Long-Term Aripiprazole in Youth with Developmental Disabilities Including Autism

    ERIC Educational Resources Information Center

    Hellings, Jessica A.; Boehm, Danna; Yeh, Hung Wen; Butler, Merlin G.; Schroeder, Stephen R.

    2011-01-01

    We retrospectively reviewed clinic charts of 21 children and adolescents with developmental disabilities including autism spectrum disorders (ASD) treated consecutively with aripiprazole (ARI) for irritability and severe challenging behaviors. Data extracted include age, sex, and race; level of intellectual disability (ID); "Diagnostic and…

  3. Are Anxiety and Depression Addressed in Primary Care Patients With Chronic Obstructive Pulmonary Disease? A Chart Review

    PubMed Central

    Roundy, Kent; Cully, Jeffrey A.; Stanley, Melinda A.; Veazey, Connie; Souchek, Julianne; Wray, Nelda P.; Kunik, Mark E.

    2005-01-01

    Objective: Screening for mental illness in primary care is widely recommended, but little is known about the evaluation, treatment, and long-term management processes that follow screening. The aim of this study was to examine and describe the quality of mental health care for persons with chronic obstructive pulmonary disease (COPD) and anxiety/depressive disorders, as measured by adherence to practice guidelines. Method: This retrospective chart review examined data for 102 primary care and mental health care patients with COPD who were diagnosed, using Structured Clinical Interview for DSM-IV criteria, with major depressive disorder, dysthymia, depression not otherwise specified, generalized anxiety disorder, or anxiety not otherwise specified. Data were gathered from primary care progress notes from the year prior to enrollment in a randomized controlled trial (enrollment was from July 2002 to April 2004). We compared the care received by these patients over 1 year with that recommended by practice guidelines. Charts were abstracted using a checklist of recommended practice guidelines for diagnostic evaluation, acute treatment, and long-term management of anxiety and depressive disorders. Results: Fifty (49%) of the 102 patients were recognized during the review year as having an anxiety or depressive disorder. Eighteen patients were newly assessed for depressive or anxiety disorders during the chart review year. Patients followed in primary care alone, compared with those who were comanaged by mental health care providers, were less likely to have guideline-adherent care. Conclusion: Depressive and anxiety disorders are recognized in about half of patients; however, guideline-supported diagnostic evaluation, acute treatment (except for medications), and long-term management rarely occur in the primary care setting. To improve the treatment of depressive and anxiety disorders in primary care, the process of care delivery must be understood and changed. PMID:16308576

  4. A Structural Weight Estimation Program (SWEEP) for Aircraft. Volume 6 - Wing and Empennage Module. Appendix A: General Information for Module Flow Charts and Listings. Appendix B: Program Flow Charts, Overlays (8,0), (14,0), (15,0), (16,0) and (17,0)

    DTIC Science & Technology

    1974-06-01

    reimi /oifi I mew oo n ni I • I t»M • »’ - (I/O.. -iISIII »7. . ISIll • »I/ISM • ^■>l niKii • mi i Wi’iOui...flll>»tlllll"r A ’ torn». • rami nm • reiMi ni»i • ocm .. • cioie • i it CKDIII • nsiiii 1 IMIBl • TCIII TWllTI ■ TCm miai • «ein

  5. Issues to be Considered in the Evaluation of Technical Proposals from the Ada (Trademark) Language Perspective.

    DTIC Science & Technology

    1985-06-10

    flowcharts - hierarchical charts - data flow diagrams - finite state diagrams - control flow diagrams - decision tables/trees - entity-relationship...and beginners ; for example, is prompting via menus provided for beginners and single keystroke capability provided for experienced users? 2-13 - input

  6. Capital Budgeting Decisions with Post-Audit Information

    DTIC Science & Technology

    1990-06-08

    estimates that were used during project selection. In similar fashion, this research introduces the equivalent sample size concept that permits the... equivalent sample size is extended to include the user’s prior beliefs. 4. For a management tool, the concepts for Cash Flow Control Charts are...Acoxxting Research , vol. 7, no. 2, Autumn 1969, pp. 215-244. [9] Gaynor, Edwin W., "Use of Control Charts in Cost Control ", National Association of Cost

  7. Microscopic esophagitis and Barrett's esophagus: the histology report.

    PubMed

    Fiocca, Roberto; Mastracci, Luca; Milione, Massimo; Parente, Paola; Savarino, Vincenzo

    2011-03-01

    Gastro-esophageal reflux disease (GERD) is the most common digestive disease in industrialized countries (Europe and North America) and is associated with microscopic changes in the squamous epithelium. However, biopsy is not presently included in the routine diagnostic flow chart of GERD. In contrast, esophageal biopsy is mandatory when diagnosing Barrett's esophagus. High quality histology reports are necessary to provide information on diagnosis and can also be important for research and epidemiological studies. It has been evident for decades that pathology reports vary between institutions and even within a single institution. Standardization of reporting is the best way to ensure that information necessary for patient management is included in pathology reports. This paper details the histological criteria for diagnosing GERD-associated microscopic esophagitis, other forms of esophagitis with specific features and columnar metaplasia in the lower esophagus (Barrett's esophagus). It provides a detailed description of appropriate sampling criteria, individual lesions and how they contribute to the histology report. Copyright © 2011 Editrice Gastroenterologica Italiana S.r.l. Published by Elsevier Ltd.. All rights reserved.

  8. 14 CFR 93.57 - General rules: All segments.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... Area shall conform to the flow of traffic depicted on the appropriate aeronautical charts. (c) Each person operating a helicopter shall operate it in a manner so as to avoid the flow of airplanes. (d...) AIR TRAFFIC AND GENERAL OPERATING RULES SPECIAL AIR TRAFFIC RULES Anchorage, Alaska, Terminal Area...

  9. 14 CFR 93.57 - General rules: All segments.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Area shall conform to the flow of traffic depicted on the appropriate aeronautical charts. (c) Each person operating a helicopter shall operate it in a manner so as to avoid the flow of airplanes. (d...) AIR TRAFFIC AND GENERAL OPERATING RULES SPECIAL AIR TRAFFIC RULES Anchorage, Alaska, Terminal Area...

  10. 14 CFR 93.57 - General rules: All segments.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... Area shall conform to the flow of traffic depicted on the appropriate aeronautical charts. (c) Each person operating a helicopter shall operate it in a manner so as to avoid the flow of airplanes. (d...) AIR TRAFFIC AND GENERAL OPERATING RULES SPECIAL AIR TRAFFIC RULES Anchorage, Alaska, Terminal Area...

  11. 14 CFR 93.57 - General rules: All segments.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Area shall conform to the flow of traffic depicted on the appropriate aeronautical charts. (c) Each person operating a helicopter shall operate it in a manner so as to avoid the flow of airplanes. (d...) AIR TRAFFIC AND GENERAL OPERATING RULES SPECIAL AIR TRAFFIC RULES Anchorage, Alaska, Terminal Area...

  12. 14 CFR 93.57 - General rules: All segments.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Area shall conform to the flow of traffic depicted on the appropriate aeronautical charts. (c) Each person operating a helicopter shall operate it in a manner so as to avoid the flow of airplanes. (d...) AIR TRAFFIC AND GENERAL OPERATING RULES SPECIAL AIR TRAFFIC RULES Anchorage, Alaska, Terminal Area...

  13. A Pulsatile Cardiovascular Computer Model for Teaching Heart-Blood Vessel Interaction.

    ERIC Educational Resources Information Center

    Campbell, Kenneth; And Others

    1982-01-01

    Describes a model which gives realistic predictions of pulsatile pressure, flow, and volume events in the cardiovascular system. Includes computer oriented laboratory exercises for veterinary and graduate students; equations of the dynamic and algebraic models; and a flow chart for the cardiovascular teaching program. (JN)

  14. A general representation for axial-flow fans and turbines

    NASA Technical Reports Server (NTRS)

    Perl, W; Tucker, M

    1945-01-01

    A general representation of fan and turbine arrangements on a single classification chart is presented that is made possible by a particular definition of the stage of an axial-flow fan or turbine. Several unconventional fan and turbine arrangements are indicated and the applications of these arrangements are discussed.

  15. Verification of examination procedures in clinical laboratory for imprecision, trueness and diagnostic accuracy according to ISO 15189:2012: a pragmatic approach.

    PubMed

    Antonelli, Giorgia; Padoan, Andrea; Aita, Ada; Sciacovelli, Laura; Plebani, Mario

    2017-08-28

    Background The International Standard ISO 15189 is recognized as a valuable guide in ensuring high quality clinical laboratory services and promoting the harmonization of accreditation programmes in laboratory medicine. Examination procedures must be verified in order to guarantee that their performance characteristics are congruent with the intended scope of the test. The aim of the present study was to propose a practice model for implementing procedures employed for the verification of validated examination procedures already used for at least 2 years in our laboratory, in agreement with the ISO 15189 requirement at the Section 5.5.1.2. Methods In order to identify the operative procedure to be used, approved documents were identified, together with the definition of performance characteristics to be evaluated for the different methods; the examination procedures used in laboratory were analyzed and checked for performance specifications reported by manufacturers. Then, operative flow charts were identified to compare the laboratory performance characteristics with those declared by manufacturers. Results The choice of performance characteristics for verification was based on approved documents used as guidance, and the specific purpose tests undertaken, a consideration being made of: imprecision and trueness for quantitative methods; diagnostic accuracy for qualitative methods; imprecision together with diagnostic accuracy for semi-quantitative methods. Conclusions The described approach, balancing technological possibilities, risks and costs and assuring the compliance of the fundamental component of result accuracy, appears promising as an easily applicable and flexible procedure helping laboratories to comply with the ISO 15189 requirements.

  16. A Catalog of NASA Special Publications

    DTIC Science & Technology

    1981-01-01

    Properties and Mollier Perfect Carbon Dioxide and Nitrogen Chart for Hydrogen From 300 K to Mixtures 20 000 K Wt’. P. Peterson R. F. Kubin, L. L. Presley...human per- Avail NTIS 1964 formance. NASA SP-3006 Equilibrium Thermodynamic Properties N73-15091 938 pp of Carbon Dioxide Avail GPO 1973 H. E. Bailey...N64-25017 4 27 pp Avail GPO 1964 39 Charts for Equilibrium Flow Properties Equilibrium Thermodynamic Properties of Carbon Dioxide in Hypervelocity of

  17. Depreciation Accounting in the Uniform Chart of Accounts.

    DTIC Science & Technology

    1982-12-01

    footage of building occupied. Reason( s ) for Compute full cost of Rate setting, cash accounting for patient care flow generation and fund- depreciation ing... Horngren , Charles T., Cost Accounting ; A Managerial Emphasis, Prentice-Hall Inc., 1972. 32. Sawyer, Lawrence B., The Practice of Modern Internal Auditing...Awd ubtlft) S . TYPE or RE PORT a PE*IoO CovIERWO Master’s Thesis; Depreciation Accounting in the Uniform Dembr18 Chart of Accounts .PSOiwON.EORlumm

  18. THE ENERGETIC CHARACTERISTIC OF IONIZATION CHAMBERS (TYPE KID) DESIGNED FOR DIAGNOSTIC AND THERAPEUTIC X-RAY APPARATUS (in Polish)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lobodziec, W.

    1963-01-01

    ABS>The energy dependence characteristics of ionization chambers were determined for x rays generated in the range from 50 to 250 kev with various filtrations (Cu + Al), (Sn + Cu + Al), (simple Al) and used for diagnostic and therapeutic purposes. Tables and charts depict the results of measurements. (auth) An experimental series of counters was made with active 8 mm in order to determine the influence of miniaturization upon their characteristics. A schematic drawing shows the construction of the counter. Its cathode is made of pure

  19. Muscle Tension Dysphagia: Symptomology and Theoretical Framework.

    PubMed

    Kang, Christina H; Hentz, Joseph G; Lott, David G

    2016-11-01

    To identify symptoms, common diagnostic findings, pattern of treatments and referrals offered, and their efficacy in a group of patients with idiopathic functional dysphagia in an otolaryngology setting with multiple providers. Case series with chart review. Tertiary academic center. Following Mayo Clinic Institutional Review Board approval, a retrospective chart review was conducted of patients with dysphagia who had a videofluoroscopic swallow study between January 1, 2013, and April 30, 2015. Each patient's dysphagia symptomology, videofluoroscopic swallow study, flexible laryngoscopy, and medical chart were reviewed to identify the treatment paradigms that were utilized. Sixty-seven adult patients met the inclusion criteria. Abnormal laryngeal muscle tension was present in 97% of patients. Eighty-two percent of patients also demonstrated signs of laryngeal hyperresponsiveness. Nonspecific laryngeal inflammation was evident in 52% of patients. Twenty-seven patients were referred to speech-language pathology for evaluation. Thirteen patients completed a course of voice therapy directed toward unloading muscle tension. All 13 patients self-reported resolution of dysphagia symptoms. The study results suggest that laryngeal muscle tension may be a factor in the underlying etiology in patients with idiopathic functional dysphagia. We propose the diagnostic term muscle tension dysphagia to describe a subset of patients with functional dysphagia. Further prospective studies are needed to better evaluate potential gastroesophageal confounders in this group of patients and to identify an effective paradigm for treatment. In our limited series, speech-language pathology intervention directed toward unloading muscle tension appears effective. © American Academy of Otolaryngology—Head and Neck Surgery Foundation 2016.

  20. Multidisciplinary Developmental Evaluation Improves Early Diagnosis of Infantile Autism.

    ERIC Educational Resources Information Center

    Siegel, B.; And Others

    A life-course perspective of the diagnostic histories of 75 autistic individuals (ages 4-25) was obtained through the use of parent surveys and a review of their charts. The study was made to understand better how children who presented with uneven or unusual behavioral development are identified as developmentally multihandicapped. Areas examined…

  1. [3-channels data acquisition system based on single-chip-microcomputer used in the measurement of coronary sinus blood flow].

    PubMed

    Li, Z; Fan, Y; Chen, G

    1999-07-01

    The coronary sinus blood flow can be figured out, which based on the principle of thermodilution, so long as gets the temperature of blood, indicator and mixture of blood and indicator respectively. This system is a smart slave module with single-chip-microcomputer. The structure and principles of hardware and the flow chart of software are described in detail.

  2. Equations and charts for the rapid estimation of hinge-moment and effectiveness parameters for trailing-edge controls having leading and trailing edges swept ahead of the Mach lines

    NASA Technical Reports Server (NTRS)

    Goin, Kennith L

    1951-01-01

    Existing conical-flow solutions have been used to calculate the hinge-moments and effectiveness parameters of trailing-edge controls having leading and trailing edges swept ahead of the Mach lines and having streamwise root and tip chords. Equations and detailed charts are presented for the rapid estimation of these parameters. Also included is an approximate method by which these parameters may be corrected for airfoil-section thickness.

  3. Diagnostic laryngeal electromyography: The Wake Forest experience 1995-1999.

    PubMed

    Koufman, J A; Postma, G N; Whang, C S; Rees, C J; Amin, M R; Belafsky, P C; Johnson, P E; Connolly, K M; Walker, F O

    2001-06-01

    Laryngeal electromyography (LEMG) is a valuable diagnostic/prognostic test for patients with suspected laryngeal neuromuscular disorders. To report our experience with diagnostic LEMG at the Center for Voice Disorders of Wake Forest University and to evaluate the impact of LEMG on clinical management. Retrospective chart review of 415 patients who underwent diagnostic LEMG over a 5-year period (1995-1999). Of 415 studies, 83% (346 of 415) were abnormal, indicating a neuropathic process. LEMG results altered the diagnostic evaluation (eg, the type of radiographic imaging) in 11% (46 of 415) of the patients. Unexpected LEMG findings (eg, contralateral neuropathy) were found in 26% (107 of 415) of the patients, and LEMG results differentiated vocal fold paralysis from fixation in 12% (49 of 415). Finally, LEMG results altered the clinical management (eg, changed the timing and/or type of surgical procedure) in 40% (166 of 415) of the patients. LEMG is a valuable diagnostic test that aids the clinician in the diagnosis and management of laryngeal neuromuscular disorders.

  4. A methodology for post-EIS (environmental impact statement) monitoring

    USGS Publications Warehouse

    Marcus, Linda Graves

    1979-01-01

    A methodology for monitoring the impacts predicted in environmental impact statements (EIS's) was developed using the EIS on phosphate development in southeastern Idaho as a case study. A monitoring system based on this methodology: (1) coordinates a comprehensive, intergovernmental monitoring effort; (2) documents the major impacts that result, thereby improving the accuracy of impact predictions in future EIS's; (3) helps agencies control impacts by warning them when critical impact levels are reached and by providing feedback on the success of mitigating measures; and (4) limits monitoring data to the essential information that agencies need to carry out their regulatory and environmental protection responsibilities. The methodology is presented as flow charts accompanied by tables that describe the objectives, tasks, and products for each work element in the flow chart.

  5. Table and charts of equilibrium normal-shock and shock-tube properties for pure carbon dioxide with velocities from 1 to 16 km/sec

    NASA Technical Reports Server (NTRS)

    Miller, C. G., III; Wilder, S. E.

    1976-01-01

    Equilibrium thermodynamic and flow properties are presented in tabulated and graphical form for moving, standing, and reflected normal shock waves in pure CO2. Properties include pressure, temperature, density, enthalpy, speed of sound, entropy, molecular weight ratio, isentropic exponent, velocity, and species mole fractions. Incident (moving) shock velocities are varied from 1 to 16 km/sec for a range of initial pressure of 5 N/sq m to 500 kN/sq m. The present results are applicable to shock tube flows and to freeflight conditions for a blunt body at high velocities. Working charts illustrating idealized shock tube performance with CO2 test gas and heated helium and hydrogen driver gases are also presented.

  6. Flow Field Investigations of a Simulated Weapons Cavity at Mach 3.

    DTIC Science & Technology

    1981-12-01

    AD-Alll 843 ARMO" ENGINEERING. DEVELOPMENT CENTER ARNOLD AFS TN F/9 14/2 FLOW FIELD INVESTIGATIONS OF A SIMULATED WEAPONS CAVITY AT MACN--ETC(U) DEC...TEST CHART .. AEDC-TSR-81-V37 FLOW FIELD INVESTIGATIONS OF A _____SIMULATED WEAPONS CAVITY AT MACH 3 _~W. A. Crosby Calspan Field Services, Inc...TYPE OF REPORT & PERIOD COVERED Final Report FLOW FIELD INVESTIGATIONS OF A SIMULATED WEAPONS 27 October 1981 CAVITY AT MACH 3 6. PERFORMING O1G

  7. Knowledge Representation and Communication: Imparting Current State Information Flow to CPR Stakeholders

    PubMed Central

    de la Cruz, Norberto B.; Spiece, Leslie J.

    2000-01-01

    Understanding and communicating the who, what, where, when, why, and how of the clinics and services for which the computerized patient record (CPR) will be built is an integral part of the implementation process. Formal methodologies have been developed to diagram information flow -- flow charts, state-transition diagram (STDs), data flow diagrams (DFDs). For documentation of the processes at our ambulatory CPR pilot site, flowcharting was selected as the preferred method based upon its versatility and understandability.

  8. Feedback systems for nontraditional medicines: a case for the signal flow diagram.

    PubMed

    Tice, B S

    1998-11-01

    The signal flow diagram is a graphic method used to represent complex data that is found in the field of biology and hence the field of medicine. The signal flow diagram is analyzed against a table of data and a flow chart of data and evaluated on the clarity and simplicity of imparting this information. The data modeled is from previous clinical studies and nontraditional medicine from Africa, China, and South America. This report is a development from previous presentations of the signal flow diagram.1-4

  9. Adolescent and Caregiver use of a Tethered Personal Health Record System

    PubMed Central

    Hong, Matthew K.; Wilcox, Lauren; Feustel, Clayton; Wasileski-Masker, Karen; Olson, Thomas A.; Simoneaux, Stephen F.

    2016-01-01

    Supporting adolescent patient engagement in care is an important yet underexplored topic in consumer health informatics. Personal Health Records (PHRs) show potential, but designing PHR systems to accommodate both emerging adults and their parents is challenging. We conducted a mixed-methods study with teenage adolescent patients (ages 13-17) with cancer and blood disorders, and their parents, to investigate their experiences with My-Chart, a tethered PHR system. Through analyses of usage logs and independently-conducted surveys and interviews, we found that patients and parents both valued MyChart, but had different views about the role of the PHR for care communication and management, and different attitudes about its impact on the patient’s ability to manage care. Specific motivations for using MyChart included patient–parent coordination of care activities, communication around hospital encounters, and support for transitioning to adult care. Finally, some parents had concerns about certain diagnostic test results being made available to their children. PMID:28269859

  10. The CMC/3DPNS computer program for prediction of three-dimensional, subsonic, turbulent aerodynamic juncture region flow. Volume 3: Programmers' manual

    NASA Technical Reports Server (NTRS)

    Orzechowski, J. A.

    1982-01-01

    The CMC fluid mechanics program system was developed to transmit the theoretical evolution of finite element numerical solution methodology, applied to nonlinear field problems into a versatile computer code for comprehensive flow field analysis. A detailed view of the code from the standpoint of a computer programmer's use is presented. A system macroflow chart and detailed flow charts of several routines necessary to interact with a theoretican/user to modify the operation of this program are presented. All subroutines and details of usage, primarily for input and output routines are described. Integer and real scalars and a cross reference list denoting subroutine usage for these scalars are outlined. Entry points in dynamic storage vector IZ; the lengths of each vector accompanying the scalar definitions are described. A listing of the routines peculiar to the standard test case and a listing of the input deck and printout for this case are included.

  11. 40 CFR 161.162 - Description of production process.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... PROGRAMS DATA REQUIREMENTS FOR REGISTRATION OF ANTIMICROBIAL PESTICIDES Product Chemistry Data Requirements...) A flow chart of the chemical equations of each intended reaction occurring at each step of the...

  12. Resource impact factor (RIF) approach to optimal use of energy resources

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Jones, R.R.

    1976-10-01

    A concept called the Resource Impact Factor (RIF) is presented as a means to quantify the social value of energy resources for buildings. The flow of various raw resources from the point of extraction to the building project boundary is shown, and a flow chart indicating the decision making process is given. (PMA)

  13. Space bioreactor: Design/process flow

    NASA Technical Reports Server (NTRS)

    Cross, John H.

    1987-01-01

    The design of the space bioreactor stems from three considerations. First, and foremost, it must sustain cells in microgravity. Closely related is the ability to take advantage of the weightlessness and microgravity. Lastly, it should fit into a bioprocess. The design of the space bioreactor is described in view of these considerations. A flow chart of the bioreactor is presented and discussed.

  14. Dr. Quincy, Move Over!

    ERIC Educational Resources Information Center

    Mason, David H.

    1988-01-01

    Introduces a life science classroom activity for developing a knowledge of the human skeletal system, environmental poisoning, and bone growth pattern. Provides the situation, an organizational flow chart, relevant information materials, and directions. (YP)

  15. Association between hospital size and quality improvement for pharmaceutical services.

    PubMed

    Nau, David P; Garber, Mathew C; Lipowski, Earlene E; Stevenson, James G

    2004-01-15

    The relationship between hospital size and quality improvement (QI) for pharmaceutical services was studied. A questionnaire on QI was sent to hospital pharmacy directors in Michigan and Florida in 2002. The questionnaire included items on QI lead-team composition, QI tools, QI training, and QI culture. Usable responses were received from 162 (57%) of 282 pharmacy directors. Pharmacy QI lead teams were present in 57% of institutions, with larger teams in large hospitals (> or = 300 patients). Only two QI tools were used by a majority of hospitals: root-cause analysis (62%) and flow charts (66%). Small hospitals (< 50 patients) were less likely than medium-sized hospitals (50-299 patients) and large hospitals to use several QI tools, including control charts, cause-and-effect diagrams, root-cause analysis, flow charts, and histograms. Large hospitals were more likely than small and medium-sized hospitals to use root-cause analysis and control charts. There was no relationship between hospital size and the frequency with which physician or patient satisfaction with pharmaceutical services was measured. There were no differences in QI training or QI culture across hospital size categories. A survey suggested that a majority of hospital pharmacies in Michigan and Florida have begun to adopt QI techniques but that most are not using rigorous QI tools. Pharmacies in large hospitals had more QI lead-team members and were more likely to use certain QI tools, but there was no relationship between hospital size and satisfaction measurements, QI training, or QI culture.

  16. CHARTING A COURSE TOWARD DIAGNOSTIC MONITORING: A CONTINUING REVIEW OF CORAL REEF ATTRIBUTES AND A RESEARCH STRATEGY FOR CREATING CORAL REEF INDEXES OF BIOTIC INTEGRITY. (R825284)

    EPA Science Inventory

    The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Concl...

  17. Safe, Effective Use of Pesticides, A Manual for Commercial Applicators: Ornamental and Turf Pest Control.

    ERIC Educational Resources Information Center

    Extension Service (USDA), Washington, DC.

    This manual is intended to assist pesticide applicators in the area of ornamental and turf pest control prepare for certification under the Michigan Pesticide Control Act of 1976. The three sections presented describe: (1) Ornamentals; (2) Turfgrass; and (3) Pest Control. Section one discusses the diagnostic chart for plant problems, non-pest…

  18. ROMPS critical design review. Volume 3: Furnace module design documentation

    NASA Technical Reports Server (NTRS)

    Dobbs, M. E.

    1992-01-01

    As part of the furnace module design documentation, the furnace module Easylab programs definitions and command variables are described. Also included are Easylab commands flow charts and fault conditions.

  19. Early Grades Ideas.

    ERIC Educational Resources Information Center

    Classroom Computer Learning, 1984

    1984-01-01

    Five computer-oriented classroom activities are suggested. They include: Logo programming to help students develop estimation, logic and spatial skills; creating flow charts; inputting data; making snowflakes using Logo; and developing and using a database management program. (JN)

  20. 16 CFR 1211.5 - General testing parameters.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... condition flow chart shown in figure 1 shall be used: (1) To conduct a failure-mode and effect analysis (FMEA); (2) In investigating the performance during the Environmental Stress Tests; and (3) During the...

  1. Possible Aural Activities in the Listening Class.

    ERIC Educational Resources Information Center

    Zhiqian, Wu

    1989-01-01

    Some aural activities are described that can help language students with their listening comprehension. They include dictation, a "who am I?" exercise, sketch-drawing, chart completion, a comparison exercise, and a flow diagram. (LB)

  2. Children's growth: a health indicator and a diagnostic tool.

    PubMed

    Gelander, Lars

    2006-05-01

    The publication of Werner and Bodin in Acta Paediatrica should inspire countries to use the growth of children as an indicator of health. The development of databases that cover all measurements of all children that have contact with healthcare and medical care will provide new knowledge in this area. Such databases will give us the opportunity to explore health in different areas of the country and to evaluate community projects in order to prevent obesity. Growth charts that are used to identify sick children or children that have other causes for growth disturbances must reflect how a healthy child should grow. If such prescriptive growth charts are computerized together with regional databases, they will provide necessary growth data for descriptive health surveys.

  3. Paper to Electronic Questionnaires: Effects on Structured Questionnaire Forms

    NASA Technical Reports Server (NTRS)

    Trujillo, Anna C.

    2009-01-01

    With the use of computers, paper questionnaires are being replaced by electronic questionnaires. The formats of traditional paper questionnaires have been found to effect a subject's rating. Consequently, the transition from paper to electronic format can subtly change results. The research presented begins to determine how electronic questionnaire formats change subjective ratings. For formats where subjects used a flow chart to arrive at their rating, starting at the worst and middle ratings of the flow charts were the most accurate but subjects took slightly more time to arrive at their answers. Except for the electronic paper format, starting at the worst rating was the most preferred. The paper and electronic paper versions had the worst accuracy. Therefore, for flowchart type of questionnaires, flowcharts should start at the worst rating and work their way up to better ratings.

  4. Fundamental aerodynamic characteristics of delta wings with leading-edge vortex flows

    NASA Technical Reports Server (NTRS)

    Wood, R. M.; Miller, D. S.

    1985-01-01

    An investigation of the aerodynamics of sharp leading-edge delta wings at supersonic speeds has been conducted. The supporting experimental data for this investigation were taken from published force, pressure, and flow-visualization data in which the Mach number normal to the wing leading edge is always less than 1.0. The individual upper- and lower-surface nonlinear characteristics for uncambered delta wings are determined and presented in three charts. The upper-surface data show that both the normal-force coefficient and minimum pressure coefficient increase nonlinearly with a decreasing slope with increasing angle of attack. The lower-surface normal-force coefficient was shown to be independent of Mach number and to increase nonlinearly, with an increasing slope, with increasing angle of attack. These charts are then used to define a wing-design space for sharp leading-edge delta wings.

  5. Tables and charts of equilibrium normal shock and shock tube solutions for pure CO2 with velocities to 16 km/second

    NASA Technical Reports Server (NTRS)

    Miller, C. G., III; Wilder, S. E.

    1974-01-01

    Equilibrium thermodynamic and flow properties are presented in tabulated and graphical form for moving, standing, and reflected normal shock waves in pure CO2, representative of Mars and Venus atmospheres. Properties include pressure, temperature, density, enthalpy, speed of sound, entropy, molecular weight ratio, isentropic exponent, velocity and species mole fractions. Incident (moving) shock velocities are varied from 1 to 16 km/sec for a range of initial pressure of 5 Newtons per square meter to 500 kilo Newtons per square meter. The present results are applicable to shock tube flows, and to free-flight conditions for a blunt body at high velocities. Working charts illustrating idealized shock-tube performance with CO2 test gas and heated helium and hydrogen driver gases are also presented.

  6. Improving the performance of univariate control charts for abnormal detection and classification

    NASA Astrophysics Data System (ADS)

    Yiakopoulos, Christos; Koutsoudaki, Maria; Gryllias, Konstantinos; Antoniadis, Ioannis

    2017-03-01

    Bearing failures in rotating machinery can cause machine breakdown and economical loss, if no effective actions are taken on time. Therefore, it is of prime importance to detect accurately the presence of faults, especially at their early stage, to prevent sequent damage and reduce costly downtime. The machinery fault diagnosis follows a roadmap of data acquisition, feature extraction and diagnostic decision making, in which mechanical vibration fault feature extraction is the foundation and the key to obtain an accurate diagnostic result. A challenge in this area is the selection of the most sensitive features for various types of fault, especially when the characteristics of failures are difficult to be extracted. Thus, a plethora of complex data-driven fault diagnosis methods are fed by prominent features, which are extracted and reduced through traditional or modern algorithms. Since most of the available datasets are captured during normal operating conditions, the last decade a number of novelty detection methods, able to work when only normal data are available, have been developed. In this study, a hybrid method combining univariate control charts and a feature extraction scheme is introduced focusing towards an abnormal change detection and classification, under the assumption that measurements under normal operating conditions of the machinery are available. The feature extraction method integrates the morphological operators and the Morlet wavelets. The effectiveness of the proposed methodology is validated on two different experimental cases with bearing faults, demonstrating that the proposed approach can improve the fault detection and classification performance of conventional control charts.

  7. Prevalence of Autism Spectrum Disorder in Children Referred for Diagnostic Autism Evaluation.

    PubMed

    Monteiro, Sonia A; Spinks-Franklin, Adiaha; Treadwell-Deering, Diane; Berry, Leandra; Sellers-Vinson, Sherry; Smith, Eboni; Proud, Monica; Voigt, Robert G

    2015-12-01

    Increased public awareness of autism spectrum disorders (ASD) and routine screening in primary care have contributed to increased requests for diagnostic ASD evaluations. However, given the scarcity of subspecialty autism diagnostic resources, overreferral of children suspected of having ASD may be contributing to long waiting lists at tertiary care autism centers and delaying diagnosis for those children who truly have ASD. To determine whether children are being excessively referred to ASD-specific diagnostic clinics, our objective was to determine the prevalence of true ASD diagnoses in children referred for diagnostic ASD evaluation. Charts of all patients referred to a regional autism center between April 2011 and August 2012 for suspicion of a possible ASD were retrospectively reviewed and demographic and clinical diagnoses abstracted. Only 214 of 348 patients evaluated (61%) received an ASD diagnosis. Thus, concerns about autism are not confirmed by an ASD diagnosis in a significant number of children. © The Author(s) 2015.

  8. The clinical evaluation of infantile nystagmus: What to do first and why

    PubMed Central

    Bertsch, Morgan; Floyd, Michael; Kehoe, Taylor; Pfeifer, Wanda; Drack, Arlene V.

    2017-01-01

    Introduction Infantile nystagmus has many causes, some life threatening. We determined the most common diagnoses in order to develop a testing algorithm. Methods Retrospective chart review. Exclusion criteria were no nystagmus, acquired after 6 months, or lack of examination. Data collected: pediatric eye examination findings, ancillary testing, order of testing, referral, and final diagnoses. Final diagnosis was defined as meeting published clinical criteria and/or confirmed by diagnostic testing. Patients with a diagnosis not meeting the definition were “unknown.” Patients with incomplete testing were “incomplete.” Patients with multiple plausible etiologies were “multifactorial.” Patients with negative complete workup were “motor.” Results 284 charts were identified; 202 met inclusion criteria. The 3 most common causes were Albinism(19%), Leber Congenital Amaurosis(LCA)(14%) and Non-LCA retinal dystrophy (13%). Anatomic retinal disorders comprised 10%, motor another 10%. The most common first test was MRI (74/202) with a diagnostic yield of 16%. For 28 MRI-first patients, nystagmus alone was the indication; for 46 MRI-first patients other neurologic signs were present. 0/28 nystagmus-only patients had a diagnostic MRI while 14/46 (30%) with neurologic signs did. Yield of ERG as first test was 56%, OCT 55%, and molecular genetic testing 47%. 90% of patients had an etiology identified. Conclusion The most common causes of infantile nystagmus were retinal disorders (56%), however the most common first test was brain MRI. For patients without other neurologic stigmata complete pediatric eye examination, ERG, OCT and molecular genetic testing had a higher yield than MRI scan. If MRI is not diagnostic, a complete ophthalmologic workup should be pursued. PMID:28177849

  9. A simulation model for wind energy storage systems. Volume 3: Program descriptions

    NASA Technical Reports Server (NTRS)

    Warren, A. W.; Edsinger, R. W.; Burroughs, J. D.

    1977-01-01

    Program descriptions, flow charts, and program listings for the SIMWEST model generation program, the simulation program, the file maintenance program, and the printer plotter program are given. For Vol 2, see .

  10. Epidemiology, Diagnosis, and Treatment of Scabies in a Dermatology Office.

    PubMed

    Anderson, Kathryn L; Strowd, Lindsay C

    Scabies is a neglected skin disease, and little is known about current incidence and treatment patterns in the United States. The purpose of this study was to examine demographic data, treatment types, success of treatment, and misdiagnosis rate of scabies in an outpatient dermatology clinic. A retrospective chart review of patients diagnosed with scabies within the past 5 years was performed. A total of 459 charts were identified, with 428 meeting inclusion criteria. Demographic data, diagnostic method, treatment choice, misdiagnosis rate, treatment failure, and itching after scabies are also reported. Children were the largest age group diagnosed with scabies, at 38%. Males (54%) were diagnosed with scabies more than females. The majority of diagnoses were made by visualizing ova, feces, or mites on light microscopy (58%). At the time of diagnosis, 45% of patients had been misdiagnosed by another provider. Topical permethrin was the most common treatment used (69%), followed by a combination of topical permethrin and oral ivermectin (23%), oral ivermectin (7%), and other treatments (1%). Our findings suggest that more accurate and faster diagnostic methods are needed to limit unnecessary treatment and expedite appropriate therapy for scabies. © Copyright 2017 by the American Board of Family Medicine.

  11. Predictive values of diagnostic codes for identifying serious hypocalcemia and dermatologic adverse events among women with postmenopausal osteoporosis in a commercial health plan database.

    PubMed

    Wang, Florence T; Xue, Fei; Ding, Yan; Ng, Eva; Critchlow, Cathy W; Dore, David D

    2018-04-10

    Post-marketing safety studies of medicines often rely on administrative claims databases to identify adverse outcomes following drug exposure. Valid ascertainment of outcomes is essential for accurate results. We aim to quantify the validity of diagnostic codes for serious hypocalcemia and dermatologic adverse events from insurance claims data among women with postmenopausal osteoporosis (PMO). We identified potential cases of serious hypocalcemia and dermatologic events through ICD-9 diagnosis codes among women with PMO within claims from a large US healthcare insurer (June 2005-May 2010). A physician adjudicated potential hypocalcemic and dermatologic events identified from the primary position on emergency department (ED) or inpatient claims through medical record review. Positive predictive values (PPVs) and 95% confidence intervals (CIs) quantified the fraction of potential cases that were confirmed. Among 165,729 patients with PMO, medical charts were obtained for 40 of 55 (73%) potential hypocalcemia cases; 16 were confirmed (PPV 40%, 95% CI 25-57%). The PPV was higher for ED than inpatient claims (82 vs. 24%). Among 265 potential dermatologic events (primarily urticaria or rash), we obtained 184 (69%) charts and confirmed 128 (PPV 70%, 95% CI 62-76%). The PPV was higher for ED than inpatient claims (77 vs. 39%). Diagnostic codes for hypocalcemia and dermatologic events may be sufficient to identify events giving rise to emergency care, but are less accurate for identifying events within hospitalizations.

  12. A Brain-Machine-Brain Interface for Rewiring of Cortical Circuitry after Traumatic Brain Injury

    DTIC Science & Technology

    2011-09-01

    cerebral cortex of a rat’s brain. The flow chart for spike discrimination algorithm is also shown. Negative threshold level (not shown in bottom left...portion of the transistor drain current can flow into its bulk due to impact ionization effect [40], greatly degrading the output impedance of the...current source. This can be solved by connecting the bulk and source of together, as also seen in Fig. 4, allowing its drain-bulk current to also flow

  13. Glutamate Receptor Aptamers and ALS

    DTIC Science & Technology

    2008-01-01

    XXGATC ACC Consensus sequence RNA library Cloning and sequencing SELEX DIAGRAM Fig. 1. (a) Flow chart of SELEX. The library we used for SELEX...recording electrode and placed ~100 µm away from the hole. The linear flow rate of the solution is 1-4 cm/s. An optical fiber through which laser light for...channel recording (26) GluR6Q 1.1 × 104 4.2 × 102 Laser-pulse photolysis (67) 1.0 × 104 4.4 × 102 Fitting (52) 1.0 × 104 Flow measurement (46

  14. High Fidelity Modeling of Field-Reversed Configuration (FRC) Thrusters (Briefing Charts)

    DTIC Science & Technology

    2017-05-24

    Converged Math → Irrelevant Solutions? Validation: Fluids Example Stoke’s Flow MARTIN, SOUSA, TRAN (AFRL/RQRS) DISTRIBUTION A - APPROVED FOR PUBLIC RELEASE...Convergence Tests Converged Math → Irrelevant Solutions? Must be Aware of Valid Assumption Regions Validation: Fluids Example Stoke’s Flow Potential...AND VALIDATION Verification: Asymptotic Models → Analytical Solutions Yields Exact Convergence Tests Converged Math → Irrelevant Solutions? Must be

  15. Diagnostic value of the flow profile in the distal descending aorta by phase-contrast magnetic resonance for predicting severe coarctation of the aorta.

    PubMed

    Muzzarelli, Stefano; Ordovas, Karen Gomes; Hope, Michael D; Meadows, Jeffery J; Higgins, Charles B; Meadows, Alison Knauth

    2011-06-01

    To compare aortic flow profiles at the level of the proximal descending (PDAo) and distal descending aorta (DDAo) in patients investigated for coarctation of the aorta (CoA), and compare their respective diagnostic value for predicting severe CoA. Diastolic flow decay in the PDAo predicts severe CoA, but flow measurements at this level are limited by flow turbulence, aliasing, and stent-related artifacts. We studied 49 patients evaluated for CoA with phase contrast magnetic resonance imaging (PC-MRI). Parameters of diastolic flow decay in the PDAo and DDAo were compared. Their respective diagnostic value was compared with the standard reference of transcatheter peak gradient ≥20 mmHg. Flow measurement in the PDAo required repeated acquisition with adjustment of encoding velocity or location of the imaging plane in 69% of patients; measurement in the DDAo was achieved in single acquisition in all cases. Parameters of diastolic flow decay in the PDAo and DDAo, including rate-corrected (RC) deceleration time and RC flow deceleration yielded a good correlation (r = 0.78; P < 0.01, and r = 0.92; P < 0.01), and a similar diagnostic value for predicting severe CoA. The highest diagnostic accuracy was achieved by RC deceleration time at DDAo (sensitivity 85%, specificity 85%). Characterization of aortic flow profiles at the DDAo offers a quick and reliable noninvasive means of assessing hemodynamically significant CoA. Copyright © 2011 Wiley-Liss, Inc.

  16. Measurement Techniques for Flow Diagnostic in ITAM Impulse Wind Tunnels

    DTIC Science & Technology

    2010-04-01

    time of wind - tunnel operation, so that oscillations caused by initial shock loads could decay and a comparatively long time period with constant flow...Flow Diagnostic in ITAM Impulse Wind Tunnels 7 - 4 RTO-EN-AVT-186 A strain-gauge pressure probe is an elastic element (membrane) in a sealed...Diagnostic in ITAM Impulse Wind Tunnels RTO-EN-AVT-186 7 - 5 probes are individually calibrated. Piezoelectric pressure gauges are based

  17. Gas dynamics. Second edition

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    John, J.E.A.

    1984-01-01

    The book treats the basic fundamentals of compressible flow and gas dynamics using a wide breadth of topical coverage. It emphasizes the clear, logical development of basic theory and applies theory to real engineering systems. New in this edition is a complete changeover from English units to SI units. New charts for computing flows containing conical shock waves and expanded tables for isentropic flow and normal shocks are featured. The text emphasizes one dimensional and internal flow, and contains: improved illustrations; many new homework problems; examples and problems involving current applications; and new Mollier diagrams for computing real gas effects.

  18. A PROPOSED CHEMICAL INFORMATION AND DATA SYSTEM. VOLUME I.

    DTIC Science & Technology

    CHEMICAL COMPOUNDS, *DATA PROCESSING, *INFORMATION RETRIEVAL, * CHEMICAL ANALYSIS, INPUT OUTPUT DEVICES, COMPUTER PROGRAMMING, CLASSIFICATION...CONFIGURATIONS, DATA STORAGE SYSTEMS, ATOMS, MOLECULES, PERFORMANCE( ENGINEERING ), MAINTENANCE, SUBJECT INDEXING, MAGNETIC TAPE, AUTOMATIC, MILITARY REQUIREMENTS, TYPEWRITERS, OPTICS, TOPOLOGY, STATISTICAL ANALYSIS, FLOW CHARTING.

  19. As-built design specification for CAMS Development Dot Data System (CDDDS)

    NASA Technical Reports Server (NTRS)

    Wehmanen, O. A.

    1979-01-01

    The CAMS development dot data system is described. Listings and flow charts of the eight programs used to maintain the data base and the 15 subroutines used in FORTRAN programs to process the data are presented.

  20. MPD thruster technology

    NASA Technical Reports Server (NTRS)

    Myers, Roger M.

    1991-01-01

    Inhouse magnetoplasmadynamic (MPD) thruster technology is discussed. The study focussed on steady state thrusters at powers of less than 1 MW. Performance measurement and diagnostics technologies were developed for high power thrusters. Also developed was a MPD computer code. The stated goals of the program are to establish: performance and life limitation; influence of applied fields; propellant effects; and scaling laws. The presentation is mostly through graphs and charts.

  1. Assessing electronic health record phenotypes against gold-standard diagnostic criteria for diabetes mellitus.

    PubMed

    Spratt, Susan E; Pereira, Katherine; Granger, Bradi B; Batch, Bryan C; Phelan, Matthew; Pencina, Michael; Miranda, Marie Lynn; Boulware, Ebony; Lucas, Joseph E; Nelson, Charlotte L; Neely, Benjamin; Goldstein, Benjamin A; Barth, Pamela; Richesson, Rachel L; Riley, Isaretta L; Corsino, Leonor; McPeek Hinz, Eugenia R; Rusincovitch, Shelley; Green, Jennifer; Barton, Anna Beth; Kelley, Carly; Hyland, Kristen; Tang, Monica; Elliott, Amanda; Ruel, Ewa; Clark, Alexander; Mabrey, Melanie; Morrissey, Kay Lyn; Rao, Jyothi; Hong, Beatrice; Pierre-Louis, Marjorie; Kelly, Katherine; Jelesoff, Nicole

    2017-04-01

    We assessed the sensitivity and specificity of 8 electronic health record (EHR)-based phenotypes for diabetes mellitus against gold-standard American Diabetes Association (ADA) diagnostic criteria via chart review by clinical experts. We identified EHR-based diabetes phenotype definitions that were developed for various purposes by a variety of users, including academic medical centers, Medicare, the New York City Health Department, and pharmacy benefit managers. We applied these definitions to a sample of 173 503 patients with records in the Duke Health System Enterprise Data Warehouse and at least 1 visit over a 5-year period (2007-2011). Of these patients, 22 679 (13%) met the criteria of 1 or more of the selected diabetes phenotype definitions. A statistically balanced sample of these patients was selected for chart review by clinical experts to determine the presence or absence of type 2 diabetes in the sample. The sensitivity (62-94%) and specificity (95-99%) of EHR-based type 2 diabetes phenotypes (compared with the gold standard ADA criteria via chart review) varied depending on the component criteria and timing of observations and measurements. Researchers using EHR-based phenotype definitions should clearly specify the characteristics that comprise the definition, variations of ADA criteria, and how different phenotype definitions and components impact the patient populations retrieved and the intended application. Careful attention to phenotype definitions is critical if the promise of leveraging EHR data to improve individual and population health is to be fulfilled. © The Author 2016. Published by Oxford University Press on behalf of the American Medical Informatics Association. All rights reserved. For Permissions, please email: journals.permissions@oup.com

  2. The diagnostic plot analysis of artesian aquifers with case studies in Table Mountain Group of South Africa

    NASA Astrophysics Data System (ADS)

    Sun, Xiaobin; Xu, Yongxin; Lin, Lixiang

    2015-05-01

    Parameter estimates of artesian aquifers where piezometric head is above ground level are largely made through free-flowing and recovery tests. The straight-line method proposed by Jacob-Lohman is often used for interpretation of flow rate measured at flowing artesian boreholes. However, the approach fails to interpret the free-flowing test data from two artesian boreholes in the fractured-rock aquifer in Table Mountain Group (TMG) of South Africa. The diagnostic plot method using the reciprocal rate derivative is adapted to evaluate the artesian aquifer properties. The variation of the derivative helps not only identify flow regimes and discern the boundary conditions, but also facilitates conceptualization of the aquifer system and selection of an appropriate model for data interpretation later on. Test data from two free-flowing tests conducted in different sites in TMG are analysed using the diagnostic plot method. Based on the results, conceptual models and appropriate approaches are developed to evaluate the aquifer properties. The advantages and limitations of using the diagnostic plot method on free-flowing test data are discussed.

  3. The Endocrine Machinery.

    ERIC Educational Resources Information Center

    Fillman, David

    1987-01-01

    Promotes a reductionist approach to teaching about the endocrine system in high school biology and anatomy courses. Encourages the study of how hormones travel to the cells and affect them. Provides suggestions for activities and discussion questions, along with sample diagrams and flow charts. (TW)

  4. Airport landside volume V : appendix B ALSIM subroutines.

    DOT National Transportation Integrated Search

    1982-06-01

    This Appendix describes the operation of ten subroutines used to support the AUXILIARY and MAIN programs of ALSIM. Flow charts and listings of all programs are provided. The major portion describes the FORTRAN subprogram FORTM which is used to read i...

  5. Sensory processing issues in young children presenting to an outpatient feeding clinic.

    PubMed

    Davis, Ann M; Bruce, Amanda S; Khasawneh, Rima; Schulz, Trina; Fox, Catherine; Dunn, Winifred

    2013-02-01

    The aim of the study was to describe the relation between sensory issues and medical complexity in a series of patients presenting to an outpatient multidisciplinary feeding team for evaluation, by a standardized measure of sensory-processing abilities. A retrospective chart review of all of the patients seen from 2004 to 2009 on 2 key variables: medical diagnostic category and short sensory profile (SSP) score. On the SSP, 67.6% of children scored in the clinical ("definite difference") range. The most common diagnostic categories were developmental (n = 23), gastrointestinal (n = 16), and neurological (n = 13). Behavioral and cardiorespiratory medical diagnostic categories were significantly related to SSP total score and SSP definite difference score. Children who present for feeding evaluation do indeed tend to have clinically elevated scores regarding sensory processing, and these elevated scores are significantly related to certain medical diagnostic categories. Future research is needed to determine why these significant relations exist as well as their implications for treatment of feeding-related issues.

  6. AST Combustion Workshop: Diagnostics Working Group Report

    NASA Technical Reports Server (NTRS)

    Locke, Randy J.; Hicks, Yolanda R.; Hanson, Ronald K.

    1996-01-01

    A workshop was convened under NASA's Advanced Subsonics Technologies (AST) Program. Many of the principal combustion diagnosticians from industry, academia, and government laboratories were assembled in the Diagnostics/Testing Subsection of this workshop to discuss the requirements and obstacles to the successful implementation of advanced diagnostic techniques to the test environment of the proposed AST combustor. The participants, who represented the major relevant areas of advanced diagnostic methods currently applied to combustion and related fields, first established the anticipated AST combustor flowfield conditions. Critical flow parameters were then examined and prioritized as to their importance to combustor/fuel injector design and manufacture, environmental concerns, and computational interests. Diagnostic techniques were then evaluated in terms of current status, merits and obstacles for each flow parameter. All evaluations are presented in tabular form and recommendations are made on the best-suited diagnostic method to implement for each flow parameter in order of applicability and intrinsic value.

  7. Antibiotic and Diagnostic Discordance Between ED Physicians and Hospitalists for Pediatric Respiratory Illness.

    PubMed

    Coon, Eric R; Maloney, Christopher G; Shen, Mark W

    2015-03-01

    Imperfect diagnostic tools make it difficult to know the extent to which a bacterial process is contributing to respiratory illness, complicating the decision to prescribe antibiotics. We sought to quantify diagnostic and antibiotic prescribing disagreements between emergency department (ED) and pediatric hospitalist physicians for children admitted with respiratory illness. Manual chart review was used to identify testing, diagnostic, and antibiotic prescribing decisions for consecutive children admitted for respiratory illness in a winter (starting February 20, 2012) and a summer (starting August 20, 2012) season to a tertiary, freestanding children's hospital. Respiratory illness diagnoses were grouped into 3 categories: bacterial, viral, and asthma. A total of 181 children admitted for respiratory illness were studied. Diagnostic discordance was significant for all 3 types of respiratory illness but greatest for bacterial (P<.001). Antibiotic prescribing discordance was significant (P<.001), with pediatric hospitalists changing therapy for 93% of patients prescribed antibiotics in the ED, including stopping antibiotics altogether for 62% of patients. Significant diagnostic and antibiotic discordance between ED and pediatric hospitalist physicians exists for children admitted to the hospital for respiratory illness. Copyright © 2015 by the American Academy of Pediatrics.

  8. The role of anti-cyclic citrullinated peptide antibodies in predicting rheumatoid arthritis.

    PubMed

    Rexhepi, Sylejman; Rexhepi, Mjellma; Sahatçiu-Meka, Vjollca; Tafaj, Argjend; Izairi, Remzi; Rexhepi, Blerta

    2011-01-01

    The study presents the results of predicting role of anti-cyclic citrullinated peptide antibodies in rheumatoid arthritis, compared to rheumatoid factor. 32 patients with rheumatoid arthritis were identified from a retrospective chart review. The results of our study show that presence of the rheumatoid factor has less diagnostic and prognostic significance than the anti-cyclic citrullinated peptide, and suggests its superiority in predicting an erosive disease course.

  9. Interrelated effects of substance use diagnosis, race, and smoking severity on abstinence initiation in dually dependent male smokers: results of a retrospective chart review.

    PubMed

    Heffner, Jaimee L; Blom, Thomas J; Camerota, Elaine; Sansone, Linda E; Bodie, Linda; Smith, Joshua; Lin, Show; Drake, J Michael; Meyer, Corey; Anthenelli, Robert M

    2007-12-01

    : Study goals were 2-fold: 1) to examine differences in demographic and clinical characteristics of smokers who fell into 3 diagnostic groups: alcohol abuse/dependence only (ALC), cocaine abuse/dependence only (COC), and mixed alcohol and cocaine abuse/dependence (ALC + COC); and 2) to determine the degree to which diagnostic grouping predicted short-term abstinence from smoking. : Retrospective chart reviews were conducted by using the treatment records of male veterans (N = 175) who participated in a voluntary smoking cessation program during their stay in residential substance dependence treatment. : The ALC group smoked more heavily, had higher levels of nicotine dependence, and reported more emotional problems than the other 2 groups. Short-term abstinence rates were high across the 3 groups (38%, 58%, and 57% for the ALC, COC, and ALC + COC groups, respectively). Lighter smoking at treatment entry, non-white race, and a diagnosis of cocaine abuse/dependence (with or without alcohol abuse/dependence) predicted short-term abstinence in the program. : Substance misusers motivated to quit smoking can initiate smoking abstinence at relatively high rates with the aid of combined pharmacotherapy and intensive group counseling. White subjects who smoke more heavily and have a diagnosis of alcohol abuse/dependence only have lower success rates for abstinence initiation.

  10. Individualized Human CAD Models: Anthropmetric Morphing and Body Tissue Layering

    DTIC Science & Technology

    2014-07-31

    Part Flow Chart of the Interaction among VBA Macros, Excel® Spreadsheet, and SolidWorks Front View of the Male and Female Soldier CAD Model...yellow highlighting. The spreadsheet is linked to the CAD model by macros created with the Visual Basic for Application ( VBA ) editor in Microsoft Excel...basically three working parts to the anthropometric morphing that are all interconnected ( VBA macros, Excel spreadsheet, and SolidWorks). The flow

  11. Documentation: Motivation and training or automation

    NASA Technical Reports Server (NTRS)

    Mouton, M. L.

    1970-01-01

    The road blocks and mental blocks in areas where automation is not taking care of basic documentation problems are discussed. Original project documentation, documentation for project maintenance, and comparison of preliminary and final documentation are described. The use of flow charts is also mentioned.

  12. 48 CFR 852.211-70 - Service data manuals.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... applicable, flow charts and narrative descriptions of software shall be provided. If programming is either...) Section IV, Principles of Operation. This section shall describe in narrative form the principles of... the recommended frequency of performance shall be included for visual inspection, cleaning...

  13. Map Your Way to a Better Lab.

    ERIC Educational Resources Information Center

    Roth, Wolff-Michael

    1990-01-01

    The use of concept maps, Vee diagrams, flow charts, and productive questions to increase student understanding of laboratory exercises and to improve student attitudes toward lab classes is discussed. Examples of each are provided. Student responses to these teaching methods are described. (CW)

  14. Multivariate statistical process control of a continuous pharmaceutical twin-screw granulation and fluid bed drying process.

    PubMed

    Silva, A F; Sarraguça, M C; Fonteyne, M; Vercruysse, J; De Leersnyder, F; Vanhoorne, V; Bostijn, N; Verstraeten, M; Vervaet, C; Remon, J P; De Beer, T; Lopes, J A

    2017-08-07

    A multivariate statistical process control (MSPC) strategy was developed for the monitoring of the ConsiGma™-25 continuous tablet manufacturing line. Thirty-five logged variables encompassing three major units, being a twin screw high shear granulator, a fluid bed dryer and a product control unit, were used to monitor the process. The MSPC strategy was based on principal component analysis of data acquired under normal operating conditions using a series of four process runs. Runs with imposed disturbances in the dryer air flow and temperature, in the granulator barrel temperature, speed and liquid mass flow and in the powder dosing unit mass flow were utilized to evaluate the model's monitoring performance. The impact of the imposed deviations to the process continuity was also evaluated using Hotelling's T 2 and Q residuals statistics control charts. The influence of the individual process variables was assessed by analyzing contribution plots at specific time points. Results show that the imposed disturbances were all detected in both control charts. Overall, the MSPC strategy was successfully developed and applied. Additionally, deviations not associated with the imposed changes were detected, mainly in the granulator barrel temperature control. Copyright © 2017 Elsevier B.V. All rights reserved.

  15. Guideline attribute and implementation preferences among physicians in multiple health systems.

    PubMed

    Stone, Tamara T; Schweikhart, Sharon B; Mantese, Annamarie; Sonnad, Seema S

    2005-01-01

    Although practice guidelines are effective in assisting providers with clinical decision making, ineffective implementation strategies often prevent their use in practice. This study aimed to understand physician preferences for guideline format, placement, content, evidence, and learning strategies in different clinical environments. Semistructured telephone interviews were conducted with 500 randomly selected physicians from 4 major US health systems who were involved in the treatment of patients with acute myocardial infarction or pediatric asthma. Paired sample t tests and Tukey's method of comparisons determined the relative ranking of physicians' guideline implementation preferences. Physicians preferred guidelines located on the front of the patient chart, in palm pilots, or in progress notes and presented as flow charts/flow diagrams, algorithms, or preprinted orders that contain strategies to minimize readmits/encourage self-management and immediate treatment flows. Discussions with colleagues and continuing medical education are the most effective strategies for encouraging guideline use, and randomized controlled trials remain the most persuasive medical evidence. Health care organizations must align guideline implementation efforts with physician preferences to encourage utilization. The results of this study reveal systematic physician preferences for guideline implementation that can be applied to clinical settings to encourage guideline use by physicians.

  16. A Multisite Survey Study of EMR Review Habits, Information Needs, and Display Preferences among Medical ICU Clinicians Evaluating New Patients.

    PubMed

    Nolan, Matthew E; Cartin-Ceba, Rodrigo; Moreno-Franco, Pablo; Pickering, Brian; Herasevich, Vitaly

    2017-10-01

    The electronic chart review habits of intensive care unit (ICU) clinicians admitting new patients are largely unknown but necessary to inform the design of existing and future critical care information systems. We conducted a survey study to assess the electronic chart review practices, information needs, workflow, and data display preferences among medical ICU clinicians admitting new patients. We surveyed rotating residents, critical care fellows, advanced practice providers, and attending physicians at three Mayo Clinic sites (Minnesota, Florida, and Arizona) via email with a single follow-up reminder message. Of 234 clinicians invited, 156 completed the full survey (67% response rate). Ninety-two percent of medical ICU clinicians performed electronic chart review for the majority of new patients. Clinicians estimated spending a median (interquartile range (IQR)) of 15 (10-20) minutes for a typical case, and 25 (15-40) minutes for complex cases, with no difference across training levels. Chart review spans 3 or more years for two-thirds of clinicians, with the most relevant categories being imaging, laboratory studies, diagnostic studies, microbiology reports, and clinical notes, although most time is spent reviewing notes. Most clinicians (77%) worry about overlooking important information due to the volume of data (74%) and inadequate display/organization (63%). Potential solutions are chronologic ordering of disparate data types, color coding, and explicit data filtering techniques. The ability to dynamically customize information display for different users and varying clinical scenarios is paramount. Electronic chart review of historical data is an important, prevalent, and potentially time-consuming activity among medical ICU clinicians who would benefit from improved information display systems. Schattauer GmbH Stuttgart.

  17. Deriving temperature and age appropriate heart rate centiles for children with acute infections.

    PubMed

    Thompson, M; Harnden, A; Perera, R; Mayon-White, R; Smith, L; McLeod, D; Mant, D

    2009-05-01

    To describe the reference range for heart rate in children aged 3 months-10 years presenting to primary care with self-limiting infections. Cross-sectional study of children presenting to primary care with suspected acute infection. Heart rate was measured using a pulse oximeter and axillary temperature using an electronic thermometer. Centile charts of heart rates expected at given temperatures for children with self-limiting infections were calculated. Ten general practice surgeries and two out-of-hours centres in England. 1933 children presenting with suspected acute infections were recruited from in-hours general practice surgeries (1050 or 54.3%) or out-of-hours centres (883 or 45.7%). After excluding children who subsequently attended hospital and those without a final diagnosis of acute infection, 1589 children were used to create the centile charts of whom (859 or 54.1%) had upper respiratory tract infections and (215 or 13.5%) non-specific viral illness. Median, 75th, 90th and 97th centiles of heart rate at each temperature level. Heart rate increased by 9.9-14.1 bpm with each 1 degrees C increment in temperature. The 50th, 75th, 90th and 97th centiles of heart rate at each temperature level are presented graphically. Age-specific centile charts of heart rates expected at different temperatures should be used by clinicians in the initial assessment of children with acute infections. The charts will identify children who have a heart rate higher than expected for a given temperature and facilitate the interpretation of changes in heart rate on reassessment. Further research on the predictive value of the centile charts is needed to optimise their diagnostic utility.

  18. Towards sensible toxicity testing for nanomaterials: proposal for the specification of test design

    NASA Astrophysics Data System (ADS)

    Potthoff, Annegret; Weil, Mirco; Meißner, Tobias; Kühnel, Dana

    2015-12-01

    During the last decade, nanomaterials (NM) were extensively tested for potential harmful effects towards humans and environmental organisms. However, a sound hazard assessment was so far hampered by uncertainties and a low comparability of test results. The reason for the low comparability is a high variation in the (1) type of NM tested with regard to raw material, size and shape and (2) procedures before and during the toxicity testing. This calls for tailored, nanomaterial-specific protocols. Here, a structured approach is proposed, intended to lead to test protocols not only tailored to specific types of nanomaterials, but also to respective test system for toxicity testing. There are existing standards on single procedures involving nanomaterials, however, not all relevant procedures are covered by standards. Hence, our approach offers a detailed way of weighting several plausible alternatives for e.g. sample preparation, in order to decide on the procedure most meaningful for a specific nanomaterial and toxicity test. A framework of several decision trees (DT) and flow charts to support testing of NM is proposed as a basis for further refinement and in-depth elaboration. DT and flow charts were drafted for (1) general procedure—physicochemical characterisation, (2) choice of test media, (3) decision on test scenario and application of NM to liquid media, (4) application of NM to the gas phase, (5) application of NM to soil and sediments, (6) dose metrics, (S1) definition of a nanomaterial, and (S2) dissolution. The applicability of the proposed approach was surveyed by using experimental data retrieved from studies on nanoscale CuO. This survey demonstrated the DT and flow charts to be a convenient tool to systematically decide upon test procedures and processes, and hence pose an important step towards harmonisation of NM testing.

  19. Outpatients flow management and ophthalmic electronic medical records system in university hospital using Yahgee Document View.

    PubMed

    Matsuo, Toshihiko; Gochi, Akira; Hirakawa, Tsuyoshi; Ito, Tadashi; Kohno, Yoshihisa

    2010-10-01

    General electronic medical records systems remain insufficient for ophthalmology outpatient clinics from the viewpoint of dealing with many ophthalmic examinations and images in a large number of patients. Filing systems for documents and images by Yahgee Document View (Yahgee, Inc.) were introduced on the platform of general electronic medical records system (Fujitsu, Inc.). Outpatients flow management system and electronic medical records system for ophthalmology were constructed. All images from ophthalmic appliances were transported to Yahgee Image by the MaxFile gateway system (P4 Medic, Inc.). The flow of outpatients going through examinations such as visual acuity testing were monitored by the list "Ophthalmology Outpatients List" by Yahgee Workflow in addition to the list "Patients Reception List" by Fujitsu. Patients' identification number was scanned with bar code readers attached to ophthalmic appliances. Dual monitors were placed in doctors' rooms to show Fujitsu Medical Records on the left-hand monitor and ophthalmic charts of Yahgee Document on the right-hand monitor. The data of manually-inputted visual acuity, automatically-exported autorefractometry and non-contact tonometry on a new template, MaxFile ED, were again automatically transported to designated boxes on ophthalmic charts of Yahgee Document. Images such as fundus photographs, fluorescein angiograms, optical coherence tomographic and ultrasound scans were viewed by Yahgee Image, and were copy-and-pasted to assigned boxes on the ophthalmic charts. Ordering such as appointments, drug prescription, fees and diagnoses input, central laboratory tests, surgical theater and ward room reservations were placed by functions of the Fujitsu electronic medical records system. The combination of the Fujitsu electronic medical records and Yahgee Document View systems enabled the University Hospital to examine the same number of outpatients as prior to the implementation of the computerized filing system.

  20. Towards sensible toxicity testing for nanomaterials: proposal for the specification of test design.

    PubMed

    Potthoff, Annegret; Weil, Mirco; Meißner, Tobias; Kühnel, Dana

    2015-12-01

    During the last decade, nanomaterials (NM) were extensively tested for potential harmful effects towards humans and environmental organisms. However, a sound hazard assessment was so far hampered by uncertainties and a low comparability of test results. The reason for the low comparability is a high variation in the (1) type of NM tested with regard to raw material, size and shape and (2) procedures before and during the toxicity testing. This calls for tailored, nanomaterial-specific protocols. Here, a structured approach is proposed, intended to lead to test protocols not only tailored to specific types of nanomaterials, but also to respective test system for toxicity testing. There are existing standards on single procedures involving nanomaterials, however, not all relevant procedures are covered by standards. Hence, our approach offers a detailed way of weighting several plausible alternatives for e.g. sample preparation, in order to decide on the procedure most meaningful for a specific nanomaterial and toxicity test. A framework of several decision trees (DT) and flow charts to support testing of NM is proposed as a basis for further refinement and in-depth elaboration. DT and flow charts were drafted for (1) general procedure-physicochemical characterisation, (2) choice of test media, (3) decision on test scenario and application of NM to liquid media, (4) application of NM to the gas phase, (5) application of NM to soil and sediments, (6) dose metrics, (S1) definition of a nanomaterial, and (S2) dissolution. The applicability of the proposed approach was surveyed by using experimental data retrieved from studies on nanoscale CuO. This survey demonstrated the DT and flow charts to be a convenient tool to systematically decide upon test procedures and processes, and hence pose an important step towards harmonisation of NM testing.

  1. Modelling a radiology department service using a VDL integrated approach.

    PubMed

    Guglielmino, Maria Gabriella; Celano, Giovanni; Costa, Antonio; Fichera, Sergio

    2009-01-01

    The healthcare industry is facing several challenges such as the reduction of costs and quality improvement of the provided services. Engineering studies could be very useful in supporting organizational and management processes. Healthcare service efficiency depends on a strong collaboration between clinical and engineering experts, especially when it comes to analyzing the system and its constraints in detail and subsequently, when it comes to deciding on the reengineering of some key activities. The purpose of this paper is to propose a case study showing how a mix of representation tools allow a manager of a radiology department to solve some human and technological resource re-organizational issues, which have to be faced due to the introduction of a new technology and a new portfolio of services. In order to simulate the activities within the radiology department and examine the relationship between human and technological resources, different visual diagrammatic language (VDL) techniques have been implemented to get knowledge about the heterogeneous factors related to the healthcare service delivery. In particular, flow charts, IDEFO diagrams and Petri nets have been integrated each other with success as a modelisation tools. The simulation study performed through the application of the aforementioned VDL techniques suggests the opportunity of re-organizing the nurse activities within the radiology department. The re-organization of a healthcare service and in particular of a radiology department by means of joint flow charts, IDEF0 diagrams and Petri nets is a poorly investigated topic in literature. This paper demonstrates how flow charts and IDEF0 can help people working within the department to understand the weak points of their organization and constitute an efficient base of knowledge for the implementation of a Petri net aimed at improving the departmental performance.

  2. Table and charts of equilibrium normal shock and shock tube properties for pure argon with velocities to 18 km/sec

    NASA Technical Reports Server (NTRS)

    Miller, C. G., III; Wilder, S. E.

    1976-01-01

    Equilibrium thermodynamic and flow properties are presented in tabulated and graphical form for moving, standing, and reflected normal shock waves in pure argon. Properties include pressure, temperature, density, enthalpy, speed of sound, entropy, molecular-weight ratio, isentropic exponent, velocity, and species mole fractions. Incident (moving) shock velocities are varied from 2 to 18 km/sec for a range of initial pressure of 5 N/sq m to 500 kN/sq m. Working charts illustrating shock tube performance with argon test gas and heated helium and hydrogen driver gases are also presented.

  3. Birth-weight charts and immigrant populations: A critical review.

    PubMed

    Urquia, Marcelo L; Sørbye, Ingvil K; Wanigaratne, Susitha

    2016-04-01

    There is an increasing body of literature focusing on differences in newborn size between different population subgroups defined by racial, ethnic, and immigration status. The interpretation of these differences as pathological or as merely reflecting normal variability is not straightforward and may have consequences for the provision of obstetric and neonatal care to minority populations. In this review, we critically assess some methodological issues affecting the assessment of newborn size and their potential implications for minority populations. In particular, we discuss the pros and cons of different types of newborn birth-weight (BW) charts (i.e., single local population-based references, minority-specific references, and a single international standard) to determine abnormal newborn size, with emphasis on immigrant populations. We conclude that size alone is not enough to inform clinical decisions and that all newborn size charts should be used as screening tools, not as diagnostic tools. Parental minority status may be regarded as a marker and used to further inquire about individual risk factors, particularly among immigrants who may not have a complete medical history in the new country. Finally, we outline areas for further research and recommendations for clinical practice. Copyright © 2015 Elsevier Ltd. All rights reserved.

  4. Technique charts for Kodak EC-L film screen system for portal localization in a 6MV X-ray beam.

    PubMed

    Sandilos, P; Antypas, C; Paraskevopoulou, C; Kouvaris, J; Vlachos, L

    2006-01-01

    Port films are used in radiotherapy for visual evaluation of the radiation fields and subsequent quantitative analysis. Common port films suffer from poor image quality compared to the simulator-diagnostic films and is desirable to determine the appropriate exposure required for the best image contrast. The aim of this work is to generate technique charts for the Kodak EC-L film screen system for use in a 6MV x-ray beam. Three homogeneous water phantoms were used to simulate head-neck, thorax and abdomen dimensions of adult human, correspondingly. The film screen system was calibrated in a 6MV x-ray beam and under various irradiation conditions. The film screen system behavior was studied as a function of phantom thickness, field size and air gap between the phantom and the film screen system. In each case the optimum film exposure which produces the maximum image contrast was determined. The generated technique charts for the EC-L film screen system and for a 6 MV x-ray beam are used in our radiotherapy department for daily quality assurance of the radiotherapy procedure.

  5. Neuroimaging of classic neuralgic amyotrophy.

    PubMed

    Lieba-Samal, Doris; Jengojan, Suren; Kasprian, Gregor; Wöber, Christian; Bodner, Gerd

    2016-12-01

    Neuralgic amyotrophy (NA) often imposes diagnostic problems. Recently, MRI and high-resolution ultrasound (HRUS) have proven useful in diagnosing peripheral nerve disorders. We performed a chart and imaging review of patients who were examined using neuroimaging and who were referred because of clinically diagnosed NA between March 1, 2014 and May 1, 2015. Six patients were included. All underwent HRUS, and 5 underwent MRI. Time from onset to evaluation ranged from 2 weeks to 6 months. HRUS showed segmental swelling of all clinically affected nerves/trunks. Atrophy of muscles was detected in those assessed >1 month after onset. MRI showed T2-weighted hyperintensity in all clinically affected nerves, except for the long thoracic nerve, and denervation edema of muscles. HRUS and MRI are valuable diagnostic tools in NA. This could change the diagnostic approach from one now focused on excluding other disorders to confirming NA through imaging markers. Muscle Nerve 54: 1079-1085, 2016. © 2016 Wiley Periodicals, Inc.

  6. Troubleshooting Computer Problems--a Teachers' Guide.

    ERIC Educational Resources Information Center

    Zeitz, Leigh

    1995-01-01

    Presents a troubleshooting flow chart for teachers and others to use when trying to figure out why their computers do not work correctly. Written mainly for Macintosh computers, the purpose of this guide is to save school technology coordinators time and to help educate teachers. (Author/LRW)

  7. Development of an Aeromedical Scientific Information System for Aviation Safety

    DTIC Science & Technology

    2008-01-01

    math- ematics, engineering, computer hardware, software , and networking, was assembled to glean the most knowledge from the complicated aeromedical...9, SPlus Enterprise Developer 8, and Insightful Miner version 7. Process flow charts were done with SmartDraw Suite Edition version 7. Static and

  8. ACHP | Section 106 Regulations Flow Chart

    Science.gov Websites

    undertaking/no potential to cause effects Undertaking is type that might affect historic properties Identify No historic properties affected Historic properties are affected Assess Adverse Effects Apply affected Resolve Adverse Effects Continue consultation Memorandum of Agreement FAILURE TO AGREE COUNCIL

  9. A Primer on Functional Analysis

    ERIC Educational Resources Information Center

    Yoman, Jerome

    2008-01-01

    This article presents principles and basic steps for practitioners to complete a functional analysis of client behavior. The emphasis is on application of functional analysis to adult mental health clients. The article includes a detailed flow chart containing all major functional diagnoses and behavioral interventions, with functional assessment…

  10. Program to Optimize Simulated Trajectories (POST). Volume 3: Programmer's manual

    NASA Technical Reports Server (NTRS)

    Brauer, G. L.; Cornick, D. E.; Habeger, A. R.; Petersen, F. M.; Stevenson, R.

    1975-01-01

    Information pertinent to the programmer and relating to the program to optimize simulated trajectories (POST) is presented. Topics discussed include: program structure and logic, subroutine listings and flow charts, and internal FORTRAN symbols. The POST core requirements are summarized along with program macrologic.

  11. Firefighting and Emergency Response Study of Advanced Composites Aircraft; Objective 1: Composite Material Damage in Minor Aircraft Fires

    DTIC Science & Technology

    2013-05-18

    26 4.3. 1-D Heat Transfer Model with Pyrolysis and Thermal Damage...Improvements and Added Features ........................................................................31 4.3.4. Pyrolysis Model Calibration... Pyrolysis Model ................................................32 Figure 25. Updated Heat Transfer Algorithm Flow Chart

  12. Tables and charts of equilibrium normal shock and shock-tube solutions for helium-hydrogen mixtures with velocities to 70 km/sec

    NASA Technical Reports Server (NTRS)

    Miller, C. G., III; Wilder, S. E.

    1974-01-01

    Equilibrium thermodynamic and flow properties are presented in tabulated and graphical form for moving, standing, and reflected normal shock waves into helium-hydrogen mixtures representative of proposed outer planet atmospheres. The volumetric compositions of these mixtures are 0.35He-0.65H2, 0.20He-0.80H2, and 0.05He-0.95H2. Properties include pressure, temperature, density, enthalpy, speed of sound, entropy, molecular-weight ratio, isentropic exponent, velocity, and species mole fractions. Incident (moving) shock velocities are varied from 4 to 70 km/sec for a range of initial pressure of 5 N/sq m to 100 kN/sq m. The present results are applicable to shock-tube flows and to free-flight conditions for a blunt body at high velocities. A working chart illustrating idealized shock-tube performance with a 0.20He-0.80H2 test gas and heated helium driver gas is also presented.

  13. An Analysis of Community Health Nurses Documentation: The Best Approach to Computerization

    PubMed Central

    Chalmers, M.

    1988-01-01

    The study explored and analyzed the actual patient-related documentation performed by a sample of community health nurses working in voluntary home health agencies. The outcome of the study was a system flow chart of that documentation and included: common components of the documentation, where in the existing systems they are recorded, when they are recorded by the nurse and why they are used by the nurses and administrative personnel in the agencies. The flow chart is suitable for use as a prototype for the development of a computer software package for the computerization of the patient-related documentation by community health nurses. General System and communication theories were used as a framework for this study. A thorough analysis of the documenation resulted in a complete and exhaustive explication of the documentation by community health nurses, as well as the identification of what parts of that documentation lend themselves most readily to computerization and what areas, if any, may not readily adapt to computerization.

  14. How can we maximize the diagnostic utility of uroflow?: ICI-RS 2017.

    PubMed

    Gammie, Andrew; Rosier, Peter; Li, Rui; Harding, Chris

    2018-01-09

    To gauge the current level of diagnostic utility of uroflowmetry and to suggest areas needing research to improve this. A summary of the debate held at the 2017 meeting of the International Consultation on Incontinence Research Society, with subsequent analysis by the authors. Limited diagnostic sensitivity and specificity exist for maximum flow rates, multiple uroflow measurements, and flow-volume nomograms. There is a lack of clarity in flow rate curve shape description and uroflow time measurement. There is a need for research to combine uroflowmetry with other non-invasive indicators. Better standardizations of test technique, flow-volume nomograms, uroflow shape descriptions, and time measurements are required. © 2017 Wiley Periodicals, Inc.

  15. A New Mixing Diagnostic and Gulf Oil Spill Movement

    NASA Astrophysics Data System (ADS)

    Mezić, Igor; Loire, S.; Fonoberov, Vladimir A.; Hogan, P.

    2010-10-01

    Chaotic advection has served as the paradigm for mixing in fluid flows with simple time dependence. Its skeletal structure is based on analysis of invariant attracting and repelling manifolds in fluid flows. Here we develop a finite-time theory for two-dimensional incompressible fluid flows with arbitrary time dependence and introduce a new mixing diagnostic based on it. Besides stretching events around attracting and repelling manifolds, this allows us to detect hyperbolic mixing zones. We used the new diagnostic to forecast the spatial location and timing of oil washing ashore in Plaquemines Parish and Grand Isle, Louisiana, and Pensacola, Florida, in May 2010 and the flow of oil toward Panama City Beach, Florida, in June 2010.

  16. Stability Analysis of High-Speed Boundary-Layer Flow with Gas Injection (Briefing Charts)

    DTIC Science & Technology

    2014-06-01

    Vitaly G. Soudakov; Ivett A Leyva 5e. TASK NUMBER 5f. WORK UNIT NUMBER Q0AF 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) 8. PERFORMING...cases of low injection rates in which the N -factors in the near field region are below the critical level, shaping can produce a significant...Release; Distribution Unlimited Stability analysis of high-speed boundary-layer flow with gas injection Alexander Fedorov and Vitaly Soudakov Moscow

  17. Simple Model of the Circulation.

    ERIC Educational Resources Information Center

    Greenway, Clive A.

    1980-01-01

    Describes a program in BASIC-11 that explores the relationships between various variables in the circulatory system and permits manipulation of several semiindependent variables to model the effects of hemorrhage, drug infusions, etc. A flow chart and accompanying sample printout are provided; the program is listed in the appendix. (CS)

  18. ACHP | Section 106 Regulations Users Guide

    Science.gov Websites

    related rules, policy issues, opinions, and guidance documents Section 106: The Rules Regulations Text Flow Chart and Explanatory Material Section-by-Section Questions and Answers Policy Statements ACHP Policy Statement on Historic Preservation and Community Revitalization Policy Statement on the ACHP's

  19. Model Experiment of Two-Dimentional Brownian Motion by Microcomputer.

    ERIC Educational Resources Information Center

    Mishima, Nobuhiko; And Others

    1980-01-01

    Describes the use of a microcomputer in studying a model experiment (Brownian particles colliding with thermal particles). A flow chart and program for the experiment are provided. Suggests that this experiment may foster a deepened understanding through mutual dialog between the student and computer. (SK)

  20. Historical and projected power requirements

    NASA Technical Reports Server (NTRS)

    Wolfe, M. G.

    1978-01-01

    Policy planning for projected space power requirements is discussed. Topics of discussion cover: (1) historical space power trends (prime power requirements and power system costs); and (2) two approaches to future space power requirements (mission/traffic model approach and advanced system scenario approach). Graphs, tables, and flow charts are presented.

  1. Systematic Technology Planning: GSFC Perspective

    NASA Technical Reports Server (NTRS)

    Steiner, Mark

    2004-01-01

    This viewgraph presentation describes the experiences of Goddard Space Flight Center (GSFC) in integrating systematic technology investment planning into the process of architecting NASA space missions. The presentation uses the assessment of a lidar mission as a case study, and illustrates integration strategies through flow charts and dynamic systems models.

  2. 40 CFR 49.139 - Rule for non-Title V operating permits.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ..., the Tribal governing body, and the Tribal, State, and local air pollution authorities having... limitation. (C) A description of the production processes and a related flow chart. (D) Identification of...; (ii) Mass balance calculations; (iii) Published, verifiable emission factors that are applicable to...

  3. Programmer's guide for the GNAT computer program (numerical analysis of stratification in supercritical oxygen)

    NASA Technical Reports Server (NTRS)

    Heinmiller, J. P.

    1971-01-01

    This document is the programmer's guide for the GNAT computer program developed under MSC/TRW Task 705-2, Apollo cryogenic storage system analysis, subtask 2, is reported. Detailed logic flow charts and compiled program listings are provided for all program elements.

  4. DORCA 2 computer program. Volume 2: Programmer's manual

    NASA Technical Reports Server (NTRS)

    Gold, B. J.

    1972-01-01

    A guide for coding the Dynamic Operational Requirements and Cost Analysis Program (DORCA 2) is presented. The manual provides a detailed operation of every subroutine, the layout in core of the major matrices and arrays, and the meaning of all program values. Flow charts are included.

  5. 40 CFR 161.162 - Description of production process.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... applicant must submit information on the production (reaction) processes used to produce the active... continuous (a single reaction process from starting materials to active ingredient), but is accomplished in...) A flow chart of the chemical equations of each intended reaction occurring at each step of the...

  6. 40 CFR 161.162 - Description of production process.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... applicant must submit information on the production (reaction) processes used to produce the active... continuous (a single reaction process from starting materials to active ingredient), but is accomplished in...) A flow chart of the chemical equations of each intended reaction occurring at each step of the...

  7. Knowledge Engineering (Or, Catching Black Cats in Dark Rooms).

    ERIC Educational Resources Information Center

    Ruyle, Kim E.

    1993-01-01

    Discusses knowledge engineering, its relationship to artificial intelligence, and possible applications to developing expert systems, job aids, and technical training. The educational background of knowledge engineers is considered; the role of subject matter experts is described; and examples of flow charts, lists, and pictorial representations…

  8. Structured Programming on the 380-Z.

    ERIC Educational Resources Information Center

    Horton, Graeme

    1983-01-01

    With the production of SBAS, a combination of language and machine allowing for a disciplined and error-free approach to teaching programming is available. Instructional strategies for use with SBAS and basic concepts (decisions, repetitions/iterations, actions/processes) are discussed. Sample flow charts and program listings are provided. (JN)

  9. Design Document. EKG Interpretation Program.

    ERIC Educational Resources Information Center

    Webb, Sandra M.

    This teaching plan is designed to assist nursing instructors assigned to advanced medical surgical nursing courses in acquainting students with the basic skills needed to perform electrocardiographic (ECG or EKG) interpretations. The first part of the teaching plan contains a statement of purpose; audience recommendations; a flow chart detailing…

  10. Calculations of Laminar Heat Transfer Around Cylinders of Arbitrary Cross Section and Transpiration-Cooled Walls with Application to Turbine Blade Cooling

    NASA Technical Reports Server (NTRS)

    Eckert, E.R.G.; Livingood, John N.B.

    1951-01-01

    An approximate method for development of flow and thermal boundary layers in laminar regime on cylinders with arbitrary cross section and transpiration-cooled walls is obtained by use of Karman's integrated momentum equation and an analogous heat-flow equation. Incompressible flow with constant property values throughout boundary layer is assumed. Shape parameters for approximated velocity and temperature profiles and functions necessary for solution of boundary-layer equations are presented as charts, reducing calculations to a minimum. The method is applied to determine local heat-transfer coefficients and surface temperature-cooled turbine blades for a given flow rate. Coolant flow distributions necessary for maintaining uniform blade temperatures are also determined.

  11. Multispectral colour analysis for quantitative evaluation of pseudoisochromatic color deficiency tests

    NASA Astrophysics Data System (ADS)

    Ozolinsh, Maris; Fomins, Sergejs

    2010-11-01

    Multispectral color analysis was used for spectral scanning of Ishihara and Rabkin color deficiency test book images. It was done using tunable liquid-crystal LC filters built in the Nuance II analyzer. Multispectral analysis keeps both, information on spatial content of tests and on spectral content. Images were taken in the range of 420-720nm with a 10nm step. We calculated retina neural activity charts taking into account cone sensitivity functions, and processed charts in order to find the visibility of latent symbols in color deficiency plates using cross-correlation technique. In such way the quantitative measure is found for each of diagnostics plate for three different color deficiency carrier types - protanopes, deutanopes and tritanopes. Multispectral color analysis allows to determine the CIE xyz color coordinates of pseudoisochromatic plate design elements and to perform statistical analysis of these data to compare the color quality of available color deficiency test books.

  12. Luteal phase deficiency and infertility: difficulties encountered in diagnosis and treatment.

    PubMed

    Annos, T; Thompson, I E; Taymor, M L

    1980-06-01

    Uncertainty concerning the importance of luteal phase defects as a cause of female infertility is closely related to problems of diagnosis. A study was undertaken of the consistency of the parameters used in daignosing luteal phase deficiency in 14 patients; results of randomized treatment regimens were also compared. Specific diagnostic criteria utilizing the basal body temperature (BBT) chart, endometrial biopsy, and progesterone levels were used. Prolactin and luteinizing hormone levels were measured at the time of progesterone determinations. Of the 29 cycles studied, only one third showed consistent abnormalities in BBT chart, endometrial biopsy, and progesterone levels. Discrepancy between the endometrial biopsy and the progesterone level occurred in at least 50% of all cycles studied. Prolactin levels were elevated in only 1 patient, suggesting a minor role for altered prolactin metabolism in luteal phase deficiency. Randomized treatment with progesterone vaginal suppositories, clomiphene citrate, and no treatment resulted in pregnancy in 5 of 14 patients (36%).

  13. Diagnosis, treatment, and prevention of selected common HIV-related opportunistic infections in the Caribbean region.

    PubMed

    Kaplan, Jonathan E

    The Caribbean region, like other resource-limited areas, lacks many of the diagnostic and treatment modalities taken for granted in richer areas of the world. The Caribbean Guidelines for the Treatment of Opportunistic Infections in Adults and Adolescents Infected With the Human Immunodeficiency Virus provides guidelines for the region for preventing and treating more than 20 opportunistic diseases reflecting the variable availability of diagnostic and treatment resources. Elements of diagnosis and prevention of tuberculosis, Pneumocystis jiroveci pneumonia, and other common opportunistic conditions in this resource-limited setting were discussed by Jonathan E. Kaplan, MD, at the first CHART Caribbean Conference on the Clinical Management of HIV/AIDS in Montego Bay, Jamaica, in June 2004.

  14. Development of Doppler Global Velocimetry as a Flow Diagnostics Tool

    NASA Technical Reports Server (NTRS)

    Meyers, James F.

    1995-01-01

    The development of Doppler global velocimetry is described from its inception to its use as a flow diagnostics tool. Its evolution is traced from an elementary one-component laboratory prototype, to a full three-component configuration operating in a wind tunnel at focal distances exceeding 15 m. As part of the developmental process, several wind tunnel flow field investigations were conducted. These included supersonic flow measurements about an oblique shock, subsonic and supersonic measurements of the vortex flow above a delta wing, and three-component measurements of a high-speed jet.

  15. Multiplexed lateral flow biosensors: Technological advances for radically improving point-of-care diagnoses.

    PubMed

    Li, Jia; Macdonald, Joanne

    2016-09-15

    Lateral flow biosensors are a leading technology in point-of-care diagnostics due to their simplicity, rapidness and low cost. Their primacy in this arena continues through technological breakthroughs such as multiplexing: the detection of more than one biomarker in a single assay. Multiplexing capacity is critical for improving diagnostic efficiency, enhancing the diagnostic precision for specific diseases and reducing diagnostic cost. Here we review, for the first time, the various types and strategies employed for creating multiplexed lateral flow biosensors. These are classified into four main categories in terms of specific application or multiplexing level, namely linear, parameter, spatial and conceptual. We describe the practical applications and implications for each approach and compare their advantages and disadvantages. Importantly, multiplexing is still subject to limitations of the traditional lateral flow biosensor, such as sensitivity and specificity. However, by pushing the limitations of the traditional medium into the multiplex arena, several technological breakthroughs are emerging with novel solutions that further expand the utility of lateral flow biosensing for point-of-care applications. Copyright © 2016 Elsevier B.V. All rights reserved.

  16. Diagnostic accuracy of referral criteria for head circumference to detect hydrocephalus in the first year of life.

    PubMed

    van Dommelen, Paula; Deurloo, Jacqueline A; Gooskens, Rob H; Verkerk, Paul H

    2015-04-01

    Increased head circumference is often the first and main sign leading to the diagnosis of hydrocephalus. Our aim is to investigate the diagnostic accuracy of referral criteria for head circumference to detect hydrocephalus in the first year of life. A reference group with longitudinal head circumference data (n = 1938) was obtained from the Social Medical Survey of Children Attending Child Health Clinics study. The case group comprised infants with hydrocephalus treated in a tertiary pediatric hospital who had not already been detected during pregnancy (n = 125). Head circumference data were available for 43 patients. Head circumference data were standardized according to gestational age-specific references. Sensitivity and specificity of a very large head circumference (>2.5 standard deviations on the growth chart) were, respectively, 72.1% (95% confidence interval [CI]: 56.3-84.7) and 97.1% (95% CI:96.2-97.8). These figures were, respectively, 74.4% (95% CI: 58.8-86.5) and 93.0% (95% CI:91.8-94.1) for a large head circumference (>2.0 standard deviation), and 76.7% (95% CI:61.4-88.2) and 96.5% (95% CI:95.6-97.3) for a very large head circumference and/or a very large (>2.5 standard deviation) progressive growth of head circumference. A very large head circumference and/or a very large progressive growth of head circumference shows the best diagnostic accuracy to detect hydrocephalus at an early stage. Gestational age-specific growth charts are recommended. Further improvements may be possible by taking into account parental head circumference. Copyright © 2015 Elsevier Inc. All rights reserved.

  17. Interobserver reproducibility in pathologist interpretation of columnar-lined esophagus.

    PubMed

    Mastracci, Luca; Piol, Nataniele; Molinaro, Luca; Pitto, Francesca; Tinelli, Carmine; De Silvestri, Annalisa; Fiocca, Roberto; Grillo, Federica

    2016-02-01

    Confirmation of endoscopically suspected esophageal metaplasia (ESEM) requires histology, but confusion in the histological definition of columnar-lined esophagus (CLE) is a longstanding problem. The aim of this study is to evaluate interpathologist variability in the interpretation of CLE. Thirty pathologists were invited to review three ten-case sets of CLE biopsies. In the first set, the cases were provided with descriptive endoscopy only; in the second and the third sets, ESEM extent using Prague criteria was provided. Moreover, participants were required to refer to a diagnostic chart for evaluation of the third set. Agreement was statistically assessed using Randolph's free-marginal multirater kappa. While substantial agreement in recognizing columnar epithelium (K = 0.76) was recorded, the overall concordance in clinico-pathological diagnosis was low (K = 0.38). The overall concordance rate improved from the first (K = 0.27) to the second (K = 0.40) and third step (K = 0.46). Agreement was substantial when diagnosing Barrett's esophagus (BE) with intestinal metaplasia or inlet patch (K = 0.65 and K = 0.89), respectively, in the third step, while major problems in interpretation of CLE were observed when only cardia/cardia-oxyntic atrophic-type epithelium was present (K = 0.05-0.29). In conclusion, precise endoscopic description and the use of a diagnostic chart increased consistency in CLE interpretation of esophageal biopsies. Agreement was substantial for some diagnostic categories (BE with intestinal metaplasia and inlet patch) with a well-defined clinical profile. Interpretation of cases with cardia/cardia-oxyntic atrophic-type epithelium, with or without ESEM, was least consistent, which reflects lack of clarity of definition and results in variable management of this entity.

  18. SPICE: exploration and analysis of post-cytometric complex multivariate datasets.

    PubMed

    Roederer, Mario; Nozzi, Joshua L; Nason, Martha C

    2011-02-01

    Polychromatic flow cytometry results in complex, multivariate datasets. To date, tools for the aggregate analysis of these datasets across multiple specimens grouped by different categorical variables, such as demographic information, have not been optimized. Often, the exploration of such datasets is accomplished by visualization of patterns with pie charts or bar charts, without easy access to statistical comparisons of measurements that comprise multiple components. Here we report on algorithms and a graphical interface we developed for these purposes. In particular, we discuss thresholding necessary for accurate representation of data in pie charts, the implications for display and comparison of normalized versus unnormalized data, and the effects of averaging when samples with significant background noise are present. Finally, we define a statistic for the nonparametric comparison of complex distributions to test for difference between groups of samples based on multi-component measurements. While originally developed to support the analysis of T cell functional profiles, these techniques are amenable to a broad range of datatypes. Published 2011 Wiley-Liss, Inc.

  19. Rates of Autism Spectrum Disorder Diagnosis Under the DSM-5 Criteria Compared to DSM-IV-TR Criteria in a Hospital-Based Clinic.

    PubMed

    Hartley-McAndrew, Michelle; Mertz, Jana; Hoffman, Martin; Crawford, Donald

    2016-04-01

    We aimed to determine whether there was a decrease in the number of children diagnosed on the autism spectrum after the implementation of the new diagnostic criteria as outlined in the Diagnostic and Statistical Manual of Mental Health Disorders Fifth Edition published in May 2013. We reviewed 1552 charts of children evaluated at the Women and Children's Hospital of Buffalo, Autism Spectrum Disorders Clinic. A comparison was made of children diagnosed with autism spectrum disorder (autism, Asperger disorder, pervasive developmental disorder-not otherwise specified) from 2010 to May 2013 using the Diagnostic and Statistical Manual of Mental Health Disorders Fourth Edition, Text Revision criteria with children diagnosed from June 2013 through June 2015 under the Diagnostic and Statistical Manual of Mental Health Disorders Fifth Edition. Using χ(2) analysis, the 2013-2015 rate of autism spectrum disorder diagnosis (39%) was significantly lower (P < 0.01) than the 2010 to May 2013 sample years rate (50%). The rate of autism spectrum disorder diagnosis was significantly lower under the recently implemented Diagnostic and Statistical Manual of Mental Health Disorders Fifth Edition criteria. Published by Elsevier Inc.

  20. Diagnosing collisions of magnetized, high energy density plasma flows using a combination of collective Thomson scattering, Faraday rotation, and interferometry (invited).

    PubMed

    Swadling, G F; Lebedev, S V; Hall, G N; Patankar, S; Stewart, N H; Smith, R A; Harvey-Thompson, A J; Burdiak, G C; de Grouchy, P; Skidmore, J; Suttle, L; Suzuki-Vidal, F; Bland, S N; Kwek, K H; Pickworth, L; Bennett, M; Hare, J D; Rozmus, W; Yuan, J

    2014-11-01

    A suite of laser based diagnostics is used to study interactions of magnetised, supersonic, radiatively cooled plasma flows produced using the Magpie pulse power generator (1.4 MA, 240 ns rise time). Collective optical Thomson scattering measures the time-resolved local flow velocity and temperature across 7-14 spatial positions. The scattering spectrum is recorded from multiple directions, allowing more accurate reconstruction of the flow velocity vectors. The areal electron density is measured using 2D interferometry; optimisation and analysis are discussed. The Faraday rotation diagnostic, operating at 1053 nm, measures the magnetic field distribution in the plasma. Measurements obtained simultaneously by these diagnostics are used to constrain analysis, increasing the accuracy of interpretation.

  1. The Allocation of Teachers in Schools--An Alternative to the Class Size Dialogue.

    ERIC Educational Resources Information Center

    Loader, David N.

    1978-01-01

    This article looks beyond class size to such specifics as teachers' load, subject electives available, subject load, and different class groupings in developing a flow chart that gives added understanding and control over the variables relating to the deployment of teachers. (Author/IRT)

  2. Think Quality! The Deming Approach Does Work in Libraries.

    ERIC Educational Resources Information Center

    Mackey, Terry; Mackey, Kitty

    1992-01-01

    Presents W. Edwards Deming's Total Quality Management method and advocates its adoption in libraries. The 14 points that form the basis of Deming's philosophy are discussed in the context of the library setting. A flow chart of the reference process and user survey questions are included. (MES)

  3. The High Cost of Eating.

    ERIC Educational Resources Information Center

    Slesnick, Irwin L.

    1983-01-01

    Discusses and provides questions for use in "Energy Flow in a Wetland," a game in which energy is examined as it passes through a wetland's food chain. Includes full-color, poster-size game board, rules, and an energy loss chart which lists calorie-consuming events organisms encounter during their lives. (JN)

  4. Public Opinion Poll Question Databases: An Evaluation

    ERIC Educational Resources Information Center

    Woods, Stephen

    2007-01-01

    This paper evaluates five polling resource: iPOLL, Polling the Nations, Gallup Brain, Public Opinion Poll Question Database, and Polls and Surveys. Content was evaluated on disclosure standards from major polling organizations, scope on a model for public opinion polls, and presentation on a flow chart discussing search limitations and usability.

  5. Blade loss transient dynamics analysis. Volume 3: User's manual for TETRA program

    NASA Technical Reports Server (NTRS)

    Black, G. R.; Gallardo, V. C.; Storace, A. S.; Sagendorph, F.

    1981-01-01

    The users manual for TETRA contains program logic, flow charts, error messages, input sheets, modeling instructions, option descriptions, input variable descriptions, and demonstration problems. The process of obtaining a NASTRAN 17.5 generated modal input file for TETRA is also described with a worked sample.

  6. Distance-Based and Distributed Learning: A Decision Tool for Education Leaders.

    ERIC Educational Resources Information Center

    McGraw, Tammy M.; Ross, John D.

    This decision tool presents a progression of data collection and decision-making strategies that can increase the effectiveness of distance-based or distributed learning instruction. A narrative and flow chart cover the following steps: (1) basic assumptions, including purpose of instruction, market scan, and financial resources; (2) needs…

  7. 14 CFR 93.69 - Special requirements, Lake Campbell and Sixmile Lake Airports.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ..., DEPARTMENT OF TRANSPORTATION (CONTINUED) AIR TRAFFIC AND GENERAL OPERATING RULES SPECIAL AIR TRAFFIC RULES... person operating an aircraft to or from Lake Campbell or Sixmile Lake Airport shall conform to the flow of traffic for the Lake operations that are depicted on the appropriate aeronautical charts. ...

  8. 14 CFR 93.69 - Special requirements, Lake Campbell and Sixmile Lake Airports.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ..., DEPARTMENT OF TRANSPORTATION (CONTINUED) AIR TRAFFIC AND GENERAL OPERATING RULES SPECIAL AIR TRAFFIC RULES... person operating an aircraft to or from Lake Campbell or Sixmile Lake Airport shall conform to the flow of traffic for the Lake operations that are depicted on the appropriate aeronautical charts. ...

  9. 14 CFR 93.69 - Special requirements, Lake Campbell and Sixmile Lake Airports.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ..., DEPARTMENT OF TRANSPORTATION (CONTINUED) AIR TRAFFIC AND GENERAL OPERATING RULES SPECIAL AIR TRAFFIC RULES... person operating an aircraft to or from Lake Campbell or Sixmile Lake Airport shall conform to the flow of traffic for the Lake operations that are depicted on the appropriate aeronautical charts. ...

  10. 14 CFR 93.67 - General rules: Bryant segment.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Airport shall conform to the flow of traffic shown on the appropriate aeronautical charts, and while in the traffic pattern, shall operate that airplane at an altitude of at least 1,000 feet MSL until... (CONTINUED) AIR TRAFFIC AND GENERAL OPERATING RULES SPECIAL AIR TRAFFIC RULES Anchorage, Alaska, Terminal...

  11. 14 CFR 93.67 - General rules: Bryant segment.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Airport shall conform to the flow of traffic shown on the appropriate aeronautical charts, and while in the traffic pattern, shall operate that airplane at an altitude of at least 1,000 feet MSL until... (CONTINUED) AIR TRAFFIC AND GENERAL OPERATING RULES SPECIAL AIR TRAFFIC RULES Anchorage, Alaska, Terminal...

  12. 14 CFR 93.69 - Special requirements, Lake Campbell and Sixmile Lake Airports.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ..., DEPARTMENT OF TRANSPORTATION (CONTINUED) AIR TRAFFIC AND GENERAL OPERATING RULES SPECIAL AIR TRAFFIC RULES... person operating an aircraft to or from Lake Campbell or Sixmile Lake Airport shall conform to the flow of traffic for the Lake operations that are depicted on the appropriate aeronautical charts. ...

  13. 14 CFR 93.67 - General rules: Bryant segment.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... Airport shall conform to the flow of traffic shown on the appropriate aeronautical charts, and while in the traffic pattern, shall operate that airplane at an altitude of at least 1,000 feet MSL until... (CONTINUED) AIR TRAFFIC AND GENERAL OPERATING RULES SPECIAL AIR TRAFFIC RULES Anchorage, Alaska, Terminal...

  14. 14 CFR 93.67 - General rules: Bryant segment.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... Airport shall conform to the flow of traffic shown on the appropriate aeronautical charts, and while in the traffic pattern, shall operate that airplane at an altitude of at least 1,000 feet MSL until... (CONTINUED) AIR TRAFFIC AND GENERAL OPERATING RULES SPECIAL AIR TRAFFIC RULES Anchorage, Alaska, Terminal...

  15. 14 CFR 93.69 - Special requirements, Lake Campbell and Sixmile Lake Airports.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ..., DEPARTMENT OF TRANSPORTATION (CONTINUED) AIR TRAFFIC AND GENERAL OPERATING RULES SPECIAL AIR TRAFFIC RULES... person operating an aircraft to or from Lake Campbell or Sixmile Lake Airport shall conform to the flow of traffic for the Lake operations that are depicted on the appropriate aeronautical charts. ...

  16. 40 CFR 49.139 - Rule for non-Title V operating permits.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... the air pollution source, the Tribal governing body, and the Tribal, State, and local air pollution... limitation. (C) A description of the production processes and a related flow chart. (D) Identification of...; (ii) Mass balance calculations; (iii) Published, verifiable emission factors that are applicable to...

  17. 40 CFR 49.139 - Rule for non-Title V operating permits.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... the air pollution source, the Tribal governing body, and the Tribal, State, and local air pollution... limitation. (C) A description of the production processes and a related flow chart. (D) Identification of...; (ii) Mass balance calculations; (iii) Published, verifiable emission factors that are applicable to...

  18. 40 CFR 49.139 - Rule for non-Title V operating permits.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... the air pollution source, the Tribal governing body, and the Tribal, State, and local air pollution... limitation. (C) A description of the production processes and a related flow chart. (D) Identification of...; (ii) Mass balance calculations; (iii) Published, verifiable emission factors that are applicable to...

  19. 40 CFR 49.139 - Rule for non-Title V operating permits.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... the air pollution source, the Tribal governing body, and the Tribal, State, and local air pollution... limitation. (C) A description of the production processes and a related flow chart. (D) Identification of...; (ii) Mass balance calculations; (iii) Published, verifiable emission factors that are applicable to...

  20. ILLIAC 4 systems characteristics and programming manual

    NASA Technical Reports Server (NTRS)

    1973-01-01

    The latest edition is presented of the Systems Characteristics and Programming Manual of the ILLIAC 4 array and parallel disc memory system. The major aspects of the array described include: the array systems characteristics, programming characteristics, definition and flow charts, and timing. A glossary of terms, and an instruction index are included.

  1. Hello! Are You Registered?

    ERIC Educational Resources Information Center

    Institute for Political/Legal Education, Sewell, NJ.

    Organizational procedures and appropriate forms for high school students to conduct a community survey of non-registered voters are provided. Duties for student coordinator, field staff, and clerical staff are described and a flow chart depicts the relationship of personnel to one another and to the community. Students are instructed to notify…

  2. A Programmable Calculator Activity, x = 1/x + 1.

    ERIC Educational Resources Information Center

    Snover, Stephen L.; Spikell, Mark A.

    An activity for secondary schools is presented and discussed which may be explored with a programmable calculator. The activity is non-standard and could not be easily explored without the use of a programmable calculator. Related activities are also discussed. Flow charts and programs for different programmable calculators are presented. (MP)

  3. Competencies and Standards for Psychological Assessment, Intervention and Follow-Up.

    ERIC Educational Resources Information Center

    Grimes, Jeff; And Others

    Intended for self evaluation and improvement of school psychological services, the document lists competencies and standards for psychological assessment, intervention, and followup of children with suspected handicapping conditions. The first section presents a flow chart and a list of standards for seven competencies: referral; definition of…

  4. A Simple Exposition of the Social Security Trust Fund.

    ERIC Educational Resources Information Center

    Holahan, William L.; Schug, Mark C.

    2000-01-01

    Discusses a strategy for teaching students about how the Social Security Trust Fund works. Explains that a flow chart is presented to the students; four terms are defined (deficit, surplus, debt, and reserve); and a new graph is prepared to show the paths of these four variables. (CMK)

  5. Lexivisions: Making Meaning through Imaging.

    ERIC Educational Resources Information Center

    Iovino, Linda

    In a high school writing workshop, students frequently would go through multiple essay drafts and conferences with the teacher and fellow students before realizing that their theses were incorrect. A teacher devised the "lexivision" to address this problem. Students used Venn diagrams, graphs, or flow charts to represent concepts in the…

  6. Transonic Compressor: Program System TXCO for Data Acquisition and On-Line Reduction.

    DTIC Science & Technology

    1980-10-01

    IMONIDAYIYEARIHOUR,IMINISEC) OS16 C ............................................................... (0S17 C 0SiB C Gel dole ond line and convert the...linear curve fits SECON real intercept of linear curve fit (as from CURVE) 65 - . FLOW CHART SUBROUTINE CALIB - - - Aso C’A / oonre& *Go wSAt*irc

  7. Teaching Economics: A Cooperative Learning Model.

    ERIC Educational Resources Information Center

    Caropreso, Edward J.; Haggerty, Mark

    2000-01-01

    Describes an alternative approach to introductory economics based on a cooperative learning model, "Learning Together." Discussion of issues in economics education and cooperative learning in higher education leads to explanation of how to adapt the Learning Together Model to lesson planning in economics. A flow chart illustrates the process for a…

  8. Patterns in Liberal Arts Curricula: A Survey of Program Models.

    ERIC Educational Resources Information Center

    Kolling, Orland W.

    Characteristics of liberal arts education and different approaches to educational modeling are examined. Attention is directed to: applications of graphic depictions; Venn-Euler diagrams to represent inclusion-exclusion phenomena as well as areas of commonality in learning processes and liberal education; the uses of flow charts for describing…

  9. Teaching the Visual Learner: The Use of Visual Summaries in Marketing Education

    ERIC Educational Resources Information Center

    Clarke, Irvine, III.; Flaherty, Theresa B.; Yankey, Michael

    2006-01-01

    Approximately 40% of college students are visual learners, preferring to be taught through pictures, diagrams, flow charts, timelines, films, and demonstrations. Yet marketing instruction remains heavily reliant on presenting content primarily through verbal cues such as written or spoken words. Without visual instruction, some students may be…

  10. Real-World Flowcharting--Willy Wonka Style!

    ERIC Educational Resources Information Center

    Noe, Kelly

    2015-01-01

    The purpose of this paper is to discuss the development, implementation and outcome of a field-based learning flow-charting project that was conducted in an accounting information systems (AIS) course. The emphasis for the project was strengthening the students' critical thinking skills. This paper advances AIS education by sharing a field-based…

  11. Solving Quantitative Problems: Guidelines for Teaching Derived from Research.

    ERIC Educational Resources Information Center

    Kramers-Pals, H.; Pilot, A.

    1988-01-01

    Presents four guidelines for teaching quantitative problem-solving based on research results: analyze difficulties of students, develop a system of heuristics, select and map key relations, and design instruction with proper orientation, exercise, and feedback. Discusses the four guidelines and uses flow charts and diagrams to show how the…

  12. Statistical and Microscopic Approach to Gas Phase Chemical Kinetics.

    ERIC Educational Resources Information Center

    Perez, J. M.; Quereda, R.

    1983-01-01

    Describes advanced undergraduate laboratory exercise examining the dependence of the rate constants and the instantaneous concentrations with the nature and energy content in a gas-phase complex reaction. Computer program (with instructions and computation flow charts) used with the exercise is available from the author. (Author/JN)

  13. Basic aerodynamic research facility for comparative studies of flow diagnostic techniques

    NASA Technical Reports Server (NTRS)

    Jones, Gregory S.; Gartrell, Luther R.; Stainback, P. Calvin

    1987-01-01

    Current flow diagnostic research efforts are focusing on higher order flow field data bases, such as those generated by laser velocimetry (LV), hot-wire anemometry, and multi-hole pressure probes. Recent low-speed comparisons of results obtained with LV and hot wires have revealed strengths and weaknesses of each instrument. A seeding study will be initiated to determine particulate tracking ability.

  14. Whole Exome Sequencing in Pediatric Neurology Patients: Clinical Implications and Estimated Cost Analysis.

    PubMed

    Nolan, Danielle; Carlson, Martha

    2016-06-01

    Genetic heterogeneity in neurologic disorders has been an obstacle to phenotype-based diagnostic testing. The authors hypothesized that information compiled via whole exome sequencing will improve clinical diagnosis and management of pediatric neurology patients. The authors performed a retrospective chart review of patients evaluated in the University of Michigan Pediatric Neurology clinic between 6/2011 and 6/2015. The authors recorded previous diagnostic testing, indications for whole exome sequencing, and whole exome sequencing results. Whole exome sequencing was recommended for 135 patients and obtained in 53 patients. Insurance barriers often precluded whole exome sequencing. The most common indication for whole exome sequencing was neurodevelopmental disorders. Whole exome sequencing improved the presumptive diagnostic rate in the patient cohort from 25% to 48%. Clinical implications included family planning, medication selection, and systemic investigation. Compared to current second tier testing, whole exome sequencing can result in lower long-term charges and more timely diagnosis. Overcoming barriers related to whole exome sequencing insurance authorization could allow for more efficient and fruitful diagnostic neurological evaluations. © The Author(s) 2016.

  15. The Elimination of Transfer Distances Is an Important Part of Hospital Design.

    PubMed

    Karvonen, Sauli; Nordback, Isto; Elo, Jussi; Havulinna, Jouni; Laine, Heikki-Jussi

    2017-04-01

    The objective of the present study was to describe how a specific patient flow analysis with from-to charts can be used in hospital design and layout planning. As part of a large renewal project at a university hospital, a detailed patient flow analysis was applied to planning the musculoskeletal surgery unit (orthopedics and traumatology, hand surgery, and plastic surgery). First, the main activities of the unit were determined. Next, the routes of all patients treated over the course of 1 year were studied, and their physical movements in the current hospital were calculated. An ideal layout of the new hospital was then generated to minimize transfer distances by placing the main activities with close to each other, according to the patient flow analysis. The actual architectural design was based on the ideal layout plan. Finally, we compared the current transfer distances to the distances patients will move in the new hospital. The methods enabled us to estimate an approximate 50% reduction in transfer distances for inpatients (from 3,100 km/year to 1,600 km/year) and 30% reduction for outpatients (from 2,100 km/year to 1,400 km/year). Patient transfers are nonvalue-added activities. This study demonstrates that a detailed patient flow analysis with from-to charts can substantially shorten transfer distances, thereby minimizing extraneous patient and personnel movements. This reduction supports productivity improvement, cross-professional teamwork, and patient safety by placing all patient flow activities close to each other. Thus, this method is a valuable additional tool in hospital design.

  16. Simulation Crisis Team Training Effect on Rural Hospital Safety Climate (SIMCRITTER)

    DTIC Science & Technology

    2008-09-01

    etc. 8. Aid Run labs, get chart, assist ICU RN Central Venous Cannulation Training S b t ti l d ti fu s an a re uc on o Related Infections Health...accurately Y Y % 100% 100% Deliver meds to bedside assistant Defibrillate/cardiovert/pace Treatment leader 0 Acquire history : AMPLE Yes 0 0 Make diagnostic...cardiac cause. Prioritize intervening in myocardial event. III. Educational Level: All levels IV. Pre-event History and Physical: See below

  17. “Waiting for DAAs”: A retrospective chart review of patients with untreated hepatitis C in Rwanda

    PubMed Central

    Gupta, Neil; Kabahizi, Jules; Mukabatsinda, Constance; Walker, Timothy David; Musabeyezu, Emmanuel; Kiromera, Athanase; Steiner, Kevin; Mukherjee, Joia; Nsanzimana, Sabin; Mbituyumuremyi, Aimable

    2017-01-01

    Background Access to treatment for hepatitis C virus (HCV) in sub-Saharan Africa is extremely limited. With the advent of direct acting antivirals (DAAs), highly effective and easy-to-deliver oral regimens are now available on the global market. This study was conducted to understand the background and characteristics of a national cohort of patients with HCV infection enrolled in care and awaiting therapy with DAAs. Methods and findings We conducted a retrospective chart review of all adult patients with confirmed HCV infection who were currently enrolled in care and treatment at the four existing hepatitis referral centers in Rwanda. Patient charts at these centers were reviewed, and routinely collected data were recorded and analyzed. Overall, 253 patients were identified; median age was 56 years (IQR: 43, 65), and 149 (58.9%) were female. Median viral load was 688,736 IU/ml and 96.7% were HCV genotype 4. As classified by FIB-4 score, 64.8% of the patients had moderate to severe fibrosis. Fibrosis stage was associated with age (OR 1.12, CI 1.09–1.17), but not with time since diagnosis, gender, treatment center, or type of insurance. There was a low frequency of documented co-morbid conditions, including hypertension, diabetes, HIV, and hepatitis B virus. Conclusions Compared to an estimated 55,000 patients eligible for HCV treatment in Rwanda, this study identified only 253 patients currently diagnosed and engaged in care, highlighting an immense treatment gap in HCV, likely due to the lack of accessible and affordable screening, diagnostic, and treatment modalities. The patients that were enrolled in care had a disproportionately advanced fibrosis stage, possibly indicating late presentation to care or lack of treatment options. In the context of newly available and effective treatment options, this study supports the overall need to accelerate access to HCV screening, diagnostics, and care and treatment services in resource-limited settings in sub-Saharan Africa. PMID:28323868

  18. "Waiting for DAAs": A retrospective chart review of patients with untreated hepatitis C in Rwanda.

    PubMed

    Gupta, Neil; Kabahizi, Jules; Mukabatsinda, Constance; Walker, Timothy David; Musabeyezu, Emmanuel; Kiromera, Athanase; Van Nuil, Jennifer Ilo; Steiner, Kevin; Mukherjee, Joia; Nsanzimana, Sabin; Mbituyumuremyi, Aimable

    2017-01-01

    Access to treatment for hepatitis C virus (HCV) in sub-Saharan Africa is extremely limited. With the advent of direct acting antivirals (DAAs), highly effective and easy-to-deliver oral regimens are now available on the global market. This study was conducted to understand the background and characteristics of a national cohort of patients with HCV infection enrolled in care and awaiting therapy with DAAs. We conducted a retrospective chart review of all adult patients with confirmed HCV infection who were currently enrolled in care and treatment at the four existing hepatitis referral centers in Rwanda. Patient charts at these centers were reviewed, and routinely collected data were recorded and analyzed. Overall, 253 patients were identified; median age was 56 years (IQR: 43, 65), and 149 (58.9%) were female. Median viral load was 688,736 IU/ml and 96.7% were HCV genotype 4. As classified by FIB-4 score, 64.8% of the patients had moderate to severe fibrosis. Fibrosis stage was associated with age (OR 1.12, CI 1.09-1.17), but not with time since diagnosis, gender, treatment center, or type of insurance. There was a low frequency of documented co-morbid conditions, including hypertension, diabetes, HIV, and hepatitis B virus. Compared to an estimated 55,000 patients eligible for HCV treatment in Rwanda, this study identified only 253 patients currently diagnosed and engaged in care, highlighting an immense treatment gap in HCV, likely due to the lack of accessible and affordable screening, diagnostic, and treatment modalities. The patients that were enrolled in care had a disproportionately advanced fibrosis stage, possibly indicating late presentation to care or lack of treatment options. In the context of newly available and effective treatment options, this study supports the overall need to accelerate access to HCV screening, diagnostics, and care and treatment services in resource-limited settings in sub-Saharan Africa.

  19. A review of reporting of participant recruitment and retention in RCTs in six major journals

    PubMed Central

    Toerien, Merran; Brookes, Sara T; Metcalfe, Chris; de Salis, Isabel; Tomlin, Zelda; Peters, Tim J; Sterne, Jonathan; Donovan, Jenny L

    2009-01-01

    Background Poor recruitment and retention of participants in randomised controlled trials (RCTs) is problematic but common. Clear and detailed reporting of participant flow is essential to assess the generalisability and comparability of RCTs. Despite improved reporting since the implementation of the CONSORT statement, important problems remain. This paper aims: (i) to update and extend previous reviews evaluating reporting of participant recruitment and retention in RCTs; (ii) to quantify the level of participation throughout RCTs. Methods We reviewed all reports of RCTs of health care interventions and/or processes with individual randomisation, published July–December 2004 in six major journals. Short, secondary or interim reports, and Phase I/II trials were excluded. Data recorded were: general RCT details; inclusion of flow diagram; participant flow throughout trial; reasons for non-participation/withdrawal; target sample sizes. Results 133 reports were reviewed. Overall, 79% included a flow diagram, but over a third were incomplete. The majority reported the flow of participants at each stage of the trial after randomisation. However, 40% failed to report the numbers assessed for eligibility. Percentages of participants retained at each stage were high: for example, 90% of eligible individuals were randomised, and 93% of those randomised were outcome assessed. On average, trials met their sample size targets. However, there were some substantial shortfalls: for example 21% of trials reporting a sample size calculation failed to achieve adequate numbers at randomisation, and 48% at outcome assessment. Reporting of losses to follow up was variable and difficult to interpret. Conclusion The majority of RCTs reported the flow of participants well after randomisation, although only two-thirds included a complete flow chart and there was great variability over the definition of "lost to follow up". Reporting of participant eligibility was poor, making assessments of recruitment practice and external validity difficult. Reporting of participant flow throughout RCTs could be improved by small changes to the CONSORT chart. PMID:19591685

  20. A review of reporting of participant recruitment and retention in RCTs in six major journals.

    PubMed

    Toerien, Merran; Brookes, Sara T; Metcalfe, Chris; de Salis, Isabel; Tomlin, Zelda; Peters, Tim J; Sterne, Jonathan; Donovan, Jenny L

    2009-07-10

    Poor recruitment and retention of participants in randomised controlled trials (RCTs) is problematic but common. Clear and detailed reporting of participant flow is essential to assess the generalisability and comparability of RCTs. Despite improved reporting since the implementation of the CONSORT statement, important problems remain. This paper aims: (i) to update and extend previous reviews evaluating reporting of participant recruitment and retention in RCTs; (ii) to quantify the level of participation throughout RCTs. We reviewed all reports of RCTs of health care interventions and/or processes with individual randomisation, published July-December 2004 in six major journals. Short, secondary or interim reports, and Phase I/II trials were excluded. Data recorded were: general RCT details; inclusion of flow diagram; participant flow throughout trial; reasons for non-participation/withdrawal; target sample sizes. 133 reports were reviewed. Overall, 79% included a flow diagram, but over a third were incomplete. The majority reported the flow of participants at each stage of the trial after randomisation. However, 40% failed to report the numbers assessed for eligibility. Percentages of participants retained at each stage were high: for example, 90% of eligible individuals were randomised, and 93% of those randomised were outcome assessed. On average, trials met their sample size targets. However, there were some substantial shortfalls: for example 21% of trials reporting a sample size calculation failed to achieve adequate numbers at randomisation, and 48% at outcome assessment. Reporting of losses to follow up was variable and difficult to interpret. The majority of RCTs reported the flow of participants well after randomisation, although only two-thirds included a complete flow chart and there was great variability over the definition of "lost to follow up". Reporting of participant eligibility was poor, making assessments of recruitment practice and external validity difficult. Reporting of participant flow throughout RCTs could be improved by small changes to the CONSORT chart.

  1. The role of flow cytometry in companion animal diagnostic medicine.

    PubMed

    Tarrant, Jacqueline M

    2005-11-01

    Flow cytometry is a powerful tool for characterising the composition of complex cell populations. The accuracy and precision of this technology for describing and enumerating cells exceeds traditional methods. The number of diagnostic veterinary laboratories with access to a dedicated machine is increasing, and there is the potential to offer a clinical flow cytometry service. The improved availability of monoclonal antibodies (mAb) to cell markers expressed by the leukocytes of companion animals, permits the implementation of comprehensive mAb panels suitable for diagnosis of lympho- and myeloproliferative disease. Reticulated erythrocyte and platelet quantification, antiglobulin assays for immune-mediated cytopenias, lymphocyte subset analysis, and immunophenotyping of lymphoma and leukemia, have been validated for companion animal samples on the flow cytometer. It is now timely to consider the role of flow cytometry in diagnostic practice, and the requirement for quality assurance and standardization of testing procedures.

  2. Multi-objective Operation Chart Optimization for Aquatic Species Habitat Conservation of Cascaded Hydropower System on Yuan River, Southwestern China

    NASA Astrophysics Data System (ADS)

    Wen, X.; Lei, X.; Fang, G.; Huang, X.

    2017-12-01

    Extensive cascading hydropower exploitation in southwestern China has been the subject of debate and conflict in recent years. Introducing limited ecological curves, a novel approach for derivation of hydropower-ecological joint operation chart of cascaded hydropower system was proposed, aiming to optimize the general hydropower and ecological benefits, and to alleviate the ecological deterioration in specific flood/dry conditions. The physical habitat simulation model is proposed initially to simulate the relationship between streamflow and physical habitat of target fish species and to determine the optimal ecological flow range of representative reach. The ecological—hydropower joint optimization model is established to produce the multi-objective operation chart of cascaded hydropower system. Finally, the limited ecological guiding curves were generated and added into the operation chart. The JS-MDS cascaded hydropower system on the Yuan River in southwestern China is employed as the research area. As the result, the proposed guiding curves could increase the hydropower production amount by 1.72% and 5.99% and optimize ecological conservation degree by 0.27% and 1.13% for JS and MDS Reservoir, respectively. Meanwhile, the ecological deterioration rate also sees a decrease from 6.11% to 1.11% for JS Reservoir and 26.67% to 3.89% for MDS Reservoir.

  3. Immune Response to Mycobacterial Infection: Lessons from Flow Cytometry

    PubMed Central

    Rovina, Nikoletta; Panagiotou, Marios; Koulouris, Nikolaos G.

    2013-01-01

    Detecting and treating active and latent tuberculosis are pivotal elements for effective infection control; yet, due to their significant inherent limitations, the diagnostic means for these two stages of tuberculosis (TB) to date remain suboptimal. This paper reviews the current diagnostic tools for mycobacterial infection and focuses on the application of flow cytometry as a promising method for rapid and reliable diagnosis of mycobacterial infection as well as discrimination between active and latent TB: it summarizes diagnostic biomarkers distinguishing the two states of infection and also features of the distinct immune response against Mycobacterium tuberculosis (Mtb) at certain stages of infection as revealed by flow cytometry to date. PMID:24376464

  4. Immune response to mycobacterial infection: lessons from flow cytometry.

    PubMed

    Rovina, Nikoletta; Panagiotou, Marios; Pontikis, Konstantinos; Kyriakopoulou, Magdalini; Koulouris, Nikolaos G; Koutsoukou, Antonia

    2013-01-01

    Detecting and treating active and latent tuberculosis are pivotal elements for effective infection control; yet, due to their significant inherent limitations, the diagnostic means for these two stages of tuberculosis (TB) to date remain suboptimal. This paper reviews the current diagnostic tools for mycobacterial infection and focuses on the application of flow cytometry as a promising method for rapid and reliable diagnosis of mycobacterial infection as well as discrimination between active and latent TB: it summarizes diagnostic biomarkers distinguishing the two states of infection and also features of the distinct immune response against Mycobacterium tuberculosis (Mtb) at certain stages of infection as revealed by flow cytometry to date.

  5. Use of a microwave diagnostics technique to measure the temperature of an axisymmetric ionized gas flow

    NASA Astrophysics Data System (ADS)

    Tsel'Sov, Iu. G.; Kondrat'ev, A. S.

    1990-12-01

    A method is developed for determining the temperature of an ionized gas on the basis of electron-density sounding. This technique is used to measure the cross-sectional temperature distribution of an axisymmetric ionized gas flow using microwave diagnostics.

  6. Syndromic surveillance using veterinary laboratory data: data pre-processing and algorithm performance evaluation

    PubMed Central

    Dórea, Fernanda C.; McEwen, Beverly J.; McNab, W. Bruce; Revie, Crawford W.; Sanchez, Javier

    2013-01-01

    Diagnostic test orders to an animal laboratory were explored as a data source for monitoring trends in the incidence of clinical syndromes in cattle. Four years of real data and over 200 simulated outbreak signals were used to compare pre-processing methods that could remove temporal effects in the data, as well as temporal aberration detection algorithms that provided high sensitivity and specificity. Weekly differencing demonstrated solid performance in removing day-of-week effects, even in series with low daily counts. For aberration detection, the results indicated that no single algorithm showed performance superior to all others across the range of outbreak scenarios simulated. Exponentially weighted moving average charts and Holt–Winters exponential smoothing demonstrated complementary performance, with the latter offering an automated method to adjust to changes in the time series that will likely occur in the future. Shewhart charts provided lower sensitivity but earlier detection in some scenarios. Cumulative sum charts did not appear to add value to the system; however, the poor performance of this algorithm was attributed to characteristics of the data monitored. These findings indicate that automated monitoring aimed at early detection of temporal aberrations will likely be most effective when a range of algorithms are implemented in parallel. PMID:23576782

  7. Syndromic surveillance using veterinary laboratory data: data pre-processing and algorithm performance evaluation.

    PubMed

    Dórea, Fernanda C; McEwen, Beverly J; McNab, W Bruce; Revie, Crawford W; Sanchez, Javier

    2013-06-06

    Diagnostic test orders to an animal laboratory were explored as a data source for monitoring trends in the incidence of clinical syndromes in cattle. Four years of real data and over 200 simulated outbreak signals were used to compare pre-processing methods that could remove temporal effects in the data, as well as temporal aberration detection algorithms that provided high sensitivity and specificity. Weekly differencing demonstrated solid performance in removing day-of-week effects, even in series with low daily counts. For aberration detection, the results indicated that no single algorithm showed performance superior to all others across the range of outbreak scenarios simulated. Exponentially weighted moving average charts and Holt-Winters exponential smoothing demonstrated complementary performance, with the latter offering an automated method to adjust to changes in the time series that will likely occur in the future. Shewhart charts provided lower sensitivity but earlier detection in some scenarios. Cumulative sum charts did not appear to add value to the system; however, the poor performance of this algorithm was attributed to characteristics of the data monitored. These findings indicate that automated monitoring aimed at early detection of temporal aberrations will likely be most effective when a range of algorithms are implemented in parallel.

  8. Estimated United States Transportation Energy Use 2005

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Smith, C A; Simon, A J; Belles, R D

    A flow chart depicting energy flow in the transportation sector of the United States economy in 2005 has been constructed from publicly available data and estimates of national energy use patterns. Approximately 31,000 trillion British Thermal Units (trBTUs) of energy were used throughout the United States in transportation activities. Vehicles used in these activities include automobiles, motorcycles, trucks, buses, airplanes, rail, and ships. The transportation sector is powered primarily by petroleum-derived fuels (gasoline, diesel and jet fuel). Biomass-derived fuels, electricity and natural gas-derived fuels are also used. The flow patterns represent a comprehensive systems view of energy used within themore » transportation sector.« less

  9. Workshop on Laser Diagnostics in Fluid Mechanics and Combustion Held in Fishermens Bend, Victoria on 30 September-1 October 1993

    DTIC Science & Technology

    1993-10-01

    S...... ~ t i . .. . . . . . . FOREWORD The development of laser- based methods for observation and measurement of fluid dynamic phenomena has...Hypersonic Flows ......................... 18 P.C. Palma, A.F.P. Houwing and R.J. Sandeman Timing Problems in Laser Based Combustion Diagnostics...A.F.P. Houwing and R.J. Sandeman Laser- Based Methods for Hypervelocity Flow and Combustion Diagnostics ...... 21 H. Rubinsztein-Dunlop, P. Barker, A

  10. Compliance Timeline and Applicability Determination for Paper and Other Web Coating National Emission Standards for Hazardous Air Pollutants (NESHAP)

    EPA Pesticide Factsheets

    This February 2003 document contains a diagram of dates and events for compliance with the NESHAP for Paper and Other Web Coating. Also on this page is an April 2004 flow chart to determine if the NESHAP applies to your facility.

  11. SRM Manual, Selected Resource Materials: Description and Evaluation.

    ERIC Educational Resources Information Center

    Alberta Dept. of Education, Edmonton. Special Educational Services Branch.

    Provided in the manual is descriptive and evaluative information on 67 instructional materials or programs frequently used with exceptional children in Alberta schools. A flow chart describes the three methods of using the manual: l) to obtain descriptive and evaluative information of an instruction program in the manual 2) to classify and record…

  12. Decision Support Systems: Applications in Statistics and Hypothesis Testing.

    ERIC Educational Resources Information Center

    Olsen, Christopher R.; Bozeman, William C.

    1988-01-01

    Discussion of the selection of appropriate statistical procedures by educators highlights a study conducted to investigate the effectiveness of decision aids in facilitating the use of appropriate statistics. Experimental groups and a control group using a printed flow chart, a computer-based decision aid, and a standard text are described. (11…

  13. STEADY-STATE DESIGN OF VERTICAL WELLS FOR LIQUIDS ADDITION AT BIOREACTOR LANDFILLS

    EPA Science Inventory

    This paper presents design charts that a landfill engineer can use for the design of a vertical well system for liquids addition at bioreactor landfills. The flow rate and lateral and vertical zones of impact of a vertical well were estimated as a function of input variables su...

  14. A Computer Course for Business Students: Teacher's Guide.

    ERIC Educational Resources Information Center

    Waterhouse, Ann

    This teacher's guide is for a course designed to teach business students the fundamentals of the BASIC language and computer programming using a series of business-oriented programs. Each lesson contains an introduction, flow charts, and computer programs. The six lesson topics are print-out and format control, count-average, withholding tax…

  15. 49 CFR 173.124 - Class 4, Divisions 4.1, 4.2 and 4.3-Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... material must be determined using the testing protocol from Figure 14.2 (Flow Chart for Assigning Self... HAZARDOUS MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION HAZARDOUS MATERIALS REGULATIONS... Assignments and Exceptions for Hazardous Materials Other Than Class 1 and Class 7 § 173.124 Class 4, Divisions...

  16. Biochemical Evolution of Iron and Copper Proteins, Substances Vital to Life

    ERIC Educational Resources Information Center

    Frieden, Earl

    1974-01-01

    Summarizes studies in the area of biochemical evolution of iron, copper, and heme proteins to provide an historical outline. Included are lists of major kinds of proteins and enzymes and charts illustrating electron flow in a cytochrome electron transport system and interconversion of jerrous to ferric ion in iron metabolism. (CC)

  17. An Improved Qualitative Analysis Procedure for Aluminum Subgroup Cations.

    ERIC Educational Resources Information Center

    Kistner, C. R.; Robinson, Patricia J.

    1983-01-01

    Describes a procedure for the qualitative analysis of aluminum subgroup cations designed to avoid failure to obtain lead or barium chromate precipitates or failure to report aluminum hydroxide when present (due to staining). Provides a flow chart and step-by-step explanation for the new procedure, indicating significantly improved student results.…

  18. Johnson-O'Malley Annual Report, Fiscal Year 1972.

    ERIC Educational Resources Information Center

    Bureau of Indian Affairs (Dept. of Interior), Washington, DC.

    Presenting narrative and tabular data re: American Indians and the Johnson-O'Malley Program, this 1972 annual report includes the following: an introduction to the JOM Program; 1972 program participation by states and districts; an historical synopsis of the JOM Program; a map of the JOM administrative areas; a flow chart depicting JOM…

  19. Installation Restoration Program. Phase I: Records Search Willow Grove Air Reserve Facility, Willow Grove, Pennsylvania.

    DTIC Science & Technology

    1984-11-01

    FLOW CHART Complet List of Location/Shtes Evaluation of Past Operations at LUste SNMe * ~Potential Hazard to Healh WelareS Reglaor Agencon consolidat...siting studies were also a part of this tions, soil, groundwater sampling and large complex project. analysis, and remedial concept engi- neering. Project

  20. Feasibility study of an Integrated Program for Aerospace-vehicle Design (IPAD) system. Volume 3: Engineering creative/evaluation processes, phase 1, task 2

    NASA Technical Reports Server (NTRS)

    Garrocq, C. A.; Hosek, J. J.

    1973-01-01

    A series of functional flow charts are considered that were developed to properly identify and record the degree of participation of the disciplines considered in this feasibility study and the type of data required in the design process.

  1. 19 CFR Appendix B to Part 191 - Sample Formats for Applications for Specific Manufacturing Drawback Rulings

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    .... When applicable, give equations of the chemical reactions. The attachment of a flow chart in addition... measurement of the merchandise used. This loss or gain is caused by atmospheric conditions, chemical reactions... finished article is intended. When applicable, give equations of the chemical reactions. The attachment of...

  2. 19 CFR Appendix B to Part 191 - Sample Formats for Applications for Specific Manufacturing Drawback Rulings

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    .... When applicable, give equations of the chemical reactions. The attachment of a flow chart in addition... measurement of the merchandise used. This loss or gain is caused by atmospheric conditions, chemical reactions... finished article is intended. When applicable, give equations of the chemical reactions. The attachment of...

  3. 19 CFR Appendix B to Part 191 - Sample Formats for Applications for Specific Manufacturing Drawback Rulings

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    .... When applicable, give equations of the chemical reactions. The attachment of a flow chart in addition... measurement of the merchandise used. This loss or gain is caused by atmospheric conditions, chemical reactions... finished article is intended. When applicable, give equations of the chemical reactions. The attachment of...

  4. Advanced Electronics. Curriculum Development. Bulletin 1778.

    ERIC Educational Resources Information Center

    Eppler, Thomas

    This document is a curriculum guide for a 180-hour course in advanced electronics for 11th and 12th grades that has four instructional units. The instructional units are orientation, discrete components, integrated circuits, and electronic systems. The document includes a course flow chart; a two-page section that describes the course, lists…

  5. 75 FR 59411 - Defense Federal Acquisition Regulation Supplement; Patents, Data, and Copyrights (DFARS Case 2010...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-27

    ....'' The items ``design details, algorithms, processes, flow charts, formulas, and related material that describe the design, organization, or structure'' of computer software had been added to the current... 252.227-7018, which serves as the post-award complement to the pre-award identification and assertion...

  6. Schedule Risk Assessment

    NASA Technical Reports Server (NTRS)

    Smith, Greg

    2003-01-01

    Schedule risk assessments determine the likelihood of finishing on time. Each task in a schedule has a varying degree of probability of being finished on time. A schedule risk assessment quantifies these probabilities by assigning values to each task. This viewgraph presentation contains a flow chart for conducting a schedule risk assessment, and profiles applicable several methods of data analysis.

  7. Assistive Technology for Students with Mild Disabilities: Update 2002. ERIC Digest.

    ERIC Educational Resources Information Center

    Behrmann, Michael; Jerome, Marci Kinas

    This digest discusses six identified areas of instruction in which assistive technology can aid students with mild disabilities. It begins by discussing how assistive technology can help the student's organization. Low-tech solutions are explained, including teaching students to organize their thoughts or work using flow-charting, task analysis,…

  8. Human Behavior Based Exploratory Model for Successful Implementation of Lean Enterprise in Industry

    ERIC Educational Resources Information Center

    Sawhney, Rupy; Chason, Stewart

    2005-01-01

    Currently available Lean tools such as Lean Assessments, Value Stream Mapping, and Process Flow Charting focus on system requirements and overlook human behavior. A need is felt for a tool that allows one to baseline personnel, determine personnel requirements and align system requirements with personnel requirements. Our exploratory model--The…

  9. ROMPS critical design review. Volume 2: Robot module design documentation

    NASA Technical Reports Server (NTRS)

    Dobbs, M. E.

    1992-01-01

    The robot module design documentation for the Remote Operated Materials Processing in Space (ROMPS) experiment is compiled. This volume presents the following information: robot module modifications; Easylab commands definitions and flowcharts; Easylab program definitions and flowcharts; robot module fault conditions and structure charts; and C-DOC flow structure and cross references.

  10. Flow-Field Surveys for Rectangular Nozzles. Supplement

    NASA Technical Reports Server (NTRS)

    Zaman, K. B. M. Q.

    2012-01-01

    Flow field survey results for three rectangular nozzles are presented for a low subsonic condition obtained primarily by hot-wire anemometry. The three nozzles have aspect ratios of 2:1, 4:1 and 8:1. A fourth case included has 2:1 aspect ratio with chevrons added to the long edges. Data on mean velocity, turbulent normal and shear stresses as well as streamwise vorticity are presented covering a streamwise distance up to sixteen equivalent diameters from the nozzle exit. These detailed flow properties, including initial boundary layer characteristics, are usually difficult to measure in high speed flows and the primary objective of the study is to aid ongoing and future computational and noise modeling efforts. This supplement contains data files, charts and source code.

  11. Flow field analysis of aircraft configurations using a numerical solution to the three-dimensional unified supersonic/hypersonic small disturbance equations, part 1

    NASA Technical Reports Server (NTRS)

    Gunness, R. C., Jr.; Knight, C. J.; Dsylva, E.

    1972-01-01

    The unified small disturbance equations are numerically solved using the well-known Lax-Wendroff finite difference technique. The method allows complete determination of the inviscid flow field and surface properties as long as the flow remains supersonic. Shock waves and other discontinuities are accounted for implicity in the numerical method. This technique was programed for general application to the three-dimensional case. The validity of the method is demonstrated by calculations on cones, axisymmetric bodies, lifting bodies, delta wings, and a conical wing/body combination. Part 1 contains the discussion of problem development and results of the study. Part 2 contains flow charts, subroutine descriptions, and a listing of the computer program.

  12. The relative frequency of common neuromuscular diagnoses in a reference center.

    PubMed

    Cotta, Ana; Paim, Júlia Filardi; Carvalho, Elmano; da-Cunha-Júnior, Antonio Lopes; Navarro, Monica M; Valicek, Jaquelin; Menezes, Miriam Melo; Nunes, Simone Vilela; Xavier-Neto, Rafael; Baptista, Sidney; Lima, Luciano Romero; Takata, Reinaldo Issao; Vargas, Antonio Pedro

    2017-11-01

    The diagnostic procedure in neuromuscular patients is complex. Knowledge of the relative frequency of neuromuscular diseases within the investigated population is important to allow the neurologist to perform the most appropriate diagnostic tests. To report the relative frequency of common neuromuscular diagnoses in a reference center. A 17-year chart review of patients with suspicion of myopathy. Among 3,412 examinations, 1,603 (46.98%) yielded confirmatory results: 782 (48.78%) underwent molecular studies, and 821 (51.21%) had muscle biopsies. The most frequent diagnoses were: dystrophinopathy 460 (28.70%), mitochondriopathy 330 (20.59%), spinal muscular atrophy 158 (9.86%), limb girdle muscular dystrophy 157 (9.79%), Steinert myotonic dystrophy 138 (8.61%), facioscapulohumeral muscular dystrophy 99 (6.17%), and other diagnoses 261 (16.28%). Using the presently-available diagnostic techniques in this service, a specific limb girdle muscular dystrophy subtype diagnosis was reached in 61% of the patients. A neuromuscular-appropriate diagnosis is important for genetic counseling, rehabilitation orientation, and early treatment of respiratory and cardiac complications.

  13. Research Electronic Data Capture (REDCap®) used as an audit tool with a built-in database.

    PubMed

    Kragelund, Signe H; Kjærsgaard, Mona; Jensen-Fangel, Søren; Leth, Rita A; Ank, Nina

    2018-05-01

    The aim of this study was to develop an audit tool with a built-in database using Research Electronic Data Capture (REDCap®) as part of an antimicrobial stewardship program at a regional hospital in the Central Denmark Region, and to analyse the need, if any, to involve more than one expert in the evaluation of cases of antimicrobial treatment, and the level of agreement among the experts. Patients treated with systemic antimicrobials in the period from 1 September 2015 to 31 August 2016 were included, in total 722 cases. Data were collected retrospectively and entered manually. The audit was based on seven flow charts regarding: (1) initiation of antimicrobial treatment (2) infection (3) prescription and administration of antimicrobials (4) discontinuation of antimicrobials (5) reassessment within 48 h after the first prescription of antimicrobials (6) microbiological sampling in the period between suspicion of infection and the first administration of antimicrobials (7) microbiological results. The audit was based on automatic calculations drawing on the entered data and on expert assessments. Initially, two experts completed the audit, and in the cases in which they disagreed, a third expert was consulted. In 31.9% of the cases, the two experts agreed on all elements of the audit. In 66.2%, the two experts reached agreement by discussing the cases. Finally, 1.9% of the cases were completed in cooperation with a third expert. The experts assessed 3406 flow charts of which they agreed on 75.8%. We succeeded in creating an audit tool with a built-in database that facilitates independent expert evaluation using REDCap. We found a large inter-observer difference that needs to be considered when constructing a project based on expert judgements. Our two experts agreed on most of the flow charts after discussion, whereas the third expert's intervention did not have any influence on the overall assessment. Copyright © 2018 Elsevier Inc. All rights reserved.

  14. A Review of Recruitment, Adherence and Drop-Out Rates in Omega-3 Polyunsaturated Fatty Acid Supplementation Trials in Children and Adolescents.

    PubMed

    van der Wurff, Inge S M; Meyer, Barbara J; de Groot, Renate H M

    2017-05-10

    The influence of n -3 long-chain polyunsaturated fatty acids ( n -3 LCPUFA) supplementation on health outcomes has been studied extensively with randomized controlled trials (RCT). In many research fields, difficulties with recruitment, adherence and high drop-out rates have been reported. However, what is unknown is how common these problems are in n -3 LCPUFA supplementation studies in children and adolescents. Therefore, this paper will review n -3 LCPUFA supplementation studies in children and adolescents with regard to recruitment, adherence and drop-out rates. The Web of Science, PubMed and Ovid databases were searched for papers reporting on RCT supplementing children and adolescents (2-18 years) with a form of n -3 LCPUFA (or placebo) for at least four weeks. As a proxy for abiding to CONSORT guidelines, we noted whether manuscripts provided a flow-chart and provided dates defining the period of recruitment and follow-up. Ninety manuscripts (reporting on 75 studies) met the inclusion criteria. The majority of the studies did not abide by the CONSORT guidelines: 55% did not provide a flow-chart, while 70% did not provide dates. The majority of studies provided minimal details about the recruitment process. Only 25 of the 75 studies reported an adherence rate which was on average 85%. Sixty-five of the 75 studies included drop-out rates which were on average 17%. Less than half of the included studies abided by the CONSORT guidelines (45% included a flow chart, while 30% reported dates). Problems with recruitment and drop-out seem to be common in n -3 LCPUFA supplementation trials in children and adolescents. However, reporting about recruitment, adherence and dropout rates was very heterogeneous and minimal in the included studies. Some techniques to improve recruitment, adherence and dropout rates were identified from the literature, however these techniques may need to be tailored to n -3 LCPUFA supplementation studies in children and adolescents.

  15. Scaling of Two-Phase Flows to Partial-Earth Gravity

    NASA Technical Reports Server (NTRS)

    Hurlbert, Kathryn M.; Witte, Larry C.

    2003-01-01

    A report presents a method of scaling, to partial-Earth gravity, of parameters that describe pressure drops and other characteristics of two-phase (liquid/ vapor) flows. The development of the method was prompted by the need for a means of designing two-phase flow systems to operate on the Moon and on Mars, using fluid-properties and flow data from terrestrial two-phase-flow experiments, thus eliminating the need for partial-gravity testing. The report presents an explicit procedure for designing an Earth-based test bed that can provide hydrodynamic similarity with two-phase fluids flowing in partial-gravity systems. The procedure does not require prior knowledge of the flow regime (i.e., the spatial orientation of the phases). The method also provides for determination of pressure drops in two-phase partial-gravity flows by use of a generalization of the classical Moody chart (previously applicable to single-phase flow only). The report presents experimental data from Mars- and Moon-activity experiments that appear to demonstrate the validity of this method.

  16. Age, gender, and voided volume dependency of peak urinary flow rate and uroflowmetry nomogram in the Indian population

    PubMed Central

    Kumar, Vikash; Dhabalia, Jayesh V.; Nelivigi, Girish G.; Punia, Mahendra S.; Suryavanshi, Manav

    2009-01-01

    Objectives: The objective of this study was measurement of urine flow parameters by a non invasive urodynamic test. Variation of flow rates based on voided volume, age, and gender are described. Different nomograms are available for different populations and racial differences of urethral physiology are described. Currently, there has been no study from the Indian population on uroflow parameters. So the purpose of this study was to establish normal reference ranges of maximum and average flow rates, to see the influence of age, gender, and voided volume on flow rates, and to chart these values in the form of a nomogram. Methods: We evaluated 1,011 uroflowmetry tests in different age groups in a healthy population (healthy relatives of our patients) 16-50 year old males, >50 year old males, 5-15 year old children, and >15 year pre-menopausal and post-menopausal females. The uroflowmetry was done using the gravitimetric method. Flow chart parameters were analyzed and statistical calculations were used for drawing uroflow nomograms. Results: Qmax values in adult males were significantly higher than in the elderly and Qmax values in young females were significantly higher than in young males. Qmax values in males increased with age until 15 years old; followed by a slow decline until reaching 50 years old followed by a rapid decline after 50 years old even after correcting voided volume. Qmax values in females increased with age until they reached age 15 followed by decline in flow rate until a pre-menopausal age followed by no significant decline in post-menopausal females. Qmax values increased with voided volume until 700 cc followed by a plateau and decline. Conclusions: Qmax values more significantly correlated with age and voided volume than Qavg. Nomograms were drawn in centile form to provide normal reference ranges. Qmax values in our population were lower than described in literature. Patients with voided volume up to 50 ml could be evaluated with a nomogram. PMID:19955668

  17. Effects of pre-analytical variables on flow cytometric diagnosis of canine lymphoma: A retrospective study (2009-2015).

    PubMed

    Comazzi, S; Cozzi, M; Bernardi, S; Zanella, D R; Aresu, L; Stefanello, D; Marconato, L; Martini, V

    2018-02-01

    Flow cytometry (FC) is increasingly being used for immunophenotyping and staging of canine lymphoma. The aim of this retrospective study was to assess pre-analytical variables that might influence the diagnostic utility of FC of lymph node (LN) fine needle aspirate (FNA) specimens from dogs with lymphoproliferative diseases. The study included 987 cases with LN FNA specimens sent for immunophenotyping that were submitted to a diagnostic laboratory in Italy from 2009 to 2015. Cases were grouped into 'diagnostic' and 'non-diagnostic'. Pre-analytical factors analysed by univariate and multivariate analyses were animal-related factors (breed, age, sex, size), operator-related factors (year, season, shipping method, submitting veterinarian) and sample-related factors (type of sample material, cellular concentration, cytological smears, artefacts). The submitting veterinarian, sample material, sample cellularity and artefacts affected the likelihood of having a diagnostic sample. The availability of specimens from different sites and of cytological smears increased the odds of obtaining a diagnostic result. Major artefacts affecting diagnostic utility included poor cellularity and the presence of dead cells. Flow cytometry on LN FNA samples yielded conclusive results in more than 90% of cases with adequate sample quality and sampling conditions. Copyright © 2018 Elsevier Ltd. All rights reserved.

  18. 21 CFR 870.1435 - Single-function, preprogrammed diagnostic computer.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 8 2014-04-01 2014-04-01 false Single-function, preprogrammed diagnostic computer... Single-function, preprogrammed diagnostic computer. (a) Identification. A single-function, preprogrammed diagnostic computer is a hard-wired computer that calculates a specific physiological or blood-flow parameter...

  19. 21 CFR 870.1435 - Single-function, preprogrammed diagnostic computer.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 8 2012-04-01 2012-04-01 false Single-function, preprogrammed diagnostic computer... Single-function, preprogrammed diagnostic computer. (a) Identification. A single-function, preprogrammed diagnostic computer is a hard-wired computer that calculates a specific physiological or blood-flow parameter...

  20. 21 CFR 870.1435 - Single-function, preprogrammed diagnostic computer.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 8 2013-04-01 2013-04-01 false Single-function, preprogrammed diagnostic computer... Single-function, preprogrammed diagnostic computer. (a) Identification. A single-function, preprogrammed diagnostic computer is a hard-wired computer that calculates a specific physiological or blood-flow parameter...

  1. 21 CFR 870.1435 - Single-function, preprogrammed diagnostic computer.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 8 2011-04-01 2011-04-01 false Single-function, preprogrammed diagnostic computer... Single-function, preprogrammed diagnostic computer. (a) Identification. A single-function, preprogrammed diagnostic computer is a hard-wired computer that calculates a specific physiological or blood-flow parameter...

  2. Nonenhanced magnetic resonance angiography (MRA) of the calf arteries at 3 Tesla: intraindividual comparison of 3D flow-dependent subtractive MRA and 2D flow-independent non-subtractive MRA.

    PubMed

    Knobloch, Gesine; Lauff, Marie-Teres; Hirsch, Sebastian; Schwenke, Carsten; Hamm, Bernd; Wagner, Moritz

    2016-12-01

    To prospectively compare 3D flow-dependent subtractive MRA vs. 2D flow-independent non-subtractive MRA for assessment of the calf arteries at 3 Tesla. Forty-two patients with peripheral arterial occlusive disease underwent nonenhanced MRA of calf arteries at 3 Tesla with 3D flow-dependent subtractive MRA (fast spin echo sequence; 3D-FSE-MRA) and 2D flow-independent non-subtractive MRA (balanced steady-state-free-precession sequence; 2D-bSSFP-MRA). Moreover, all patients underwent contrast-enhanced MRA (CE-MRA) as standard-of-reference. Two readers performed a per-segment evaluation for image quality (4 = excellent to 0 = non-diagnostic) and severity of stenosis. Image quality scores of 2D-bSSFP-MRA were significantly higher compared to 3D-FSE-MRA (medians across readers: 4 vs. 3; p < 0.0001) with lower rates of non-diagnostic vessel segments on 2D-bSSFP-MRA (reader 1: <1 % vs. 15 %; reader 2: 1 % vs. 29 %; p < 0.05). Diagnostic performance of 2D-bSSFP-MRA and 3D-FSE-MRA across readers showed sensitivities of 89 % (214/240) vs. 70 % (168/240), p = 0.0153; specificities: 91 % (840/926) vs. 63 % (585/926), p < 0.0001; and diagnostic accuracies of 90 % (1054/1166) vs. 65 % (753/1166), p < 0.0001. 2D flow-independent non-subtractive MRA (2D-bSSFP-MRA) is a robust nonenhanced MRA technique for assessment of the calf arteries at 3 Tesla with significantly higher image quality and diagnostic accuracy compared to 3D flow-dependent subtractive MRA (3D-FSE-MRA). • 2D flow-independent non-subtractive MRA (2D-bSSFP-MRA) is a robust NE-MRA technique at 3T • 2D-bSSFP-MRA outperforms 3D flow-dependent subtractive MRA (3D-FSE-MRA) as NE-MRA of calf arteries • 2D-bSSFP-MRA is a promising alternative to CE-MRA for calf PAOD evaluation.

  3. A case study of printing industry plant layout for effective production

    NASA Astrophysics Data System (ADS)

    Viswajit, T.; Teja, T. Ravi; Deepthi, Y. P.

    2017-07-01

    This paper presents the overall picture of the processes happening in printing industry. This research is aimed to improve the plant layout of existing plant. The travel time was reduced by relocating machinery. Relocation is based on systematic layout planning (SLP). The complete process of raw material entering the industry to dispatching of finished product is shown in 3-D Flow diagram. The process happening in each floor explained in detail using Flow Process chart. Travel time is reduced by 25% after modifying existing plant layout.

  4. R2D2-A Fortran Program for Two-Dimensional Chemically Reacting, Hyperthermal, Internal Flows, Volume II.

    DTIC Science & Technology

    1980-01-01

    is identified in the flow chart simply as "Compute VECT’s ( predictor solution)" and "Compute V’s ( corrector solution)." A significant portion of the...TrintoTo Tm ANDera ionT SToION 28 ITIME :1 PRINCIPAL SUBROUTINES WALLPOINT (ITER,DT) ITER - iteration index for MacCormack Algorithm (ITER=1 for predictor ...WEILERSTEIN, R RAY, 6 MILLER F33615-7- C -3016UNLASSIFIED GASL-TR-254-VBL-2 AFFDL-TR-79-3162-VOL-2 NII III hImllllllllll EIEIIIIIIEIIEE EEIIIIIIIIIIII H

  5. Studies on transonic Double Circular Arc (DCA) profiles of axial flow compressor calculations of profile design

    NASA Astrophysics Data System (ADS)

    Rugun, Y.; Zhaoyan, Q.

    1986-05-01

    In this paper, the concepts and methods for design of high-Mach-number airfoils of axial flow compressor are described. The correlation-equations of main parameters such as geometries of airfoil and cascade, stream parameters and wake characteristic parameters of compressor are provided. For obtaining the total pressure loss coefficients of cascade and adopting the simplified calculating method, several curves and charts are provided by authors. The testing results and calculating values are compared, and both the results are in better agreement.

  6. The effect of prewhirl on the internal aerodynamics and performance of a mixed flow research centrifugal compressor

    NASA Technical Reports Server (NTRS)

    Bryan, William B.; Fleeter, Sanford

    1987-01-01

    The internal three-dimensional steady and time-varying flow through the diffusing elements of a centrifugal impeller were investigated using a moderate scale, subsonic, mixed flow research compressor facility. The characteristics of the test facility which permit the measurement of internal flow conditions throughout the entire research compressor and radial diffuser for various operating conditions are described. Results are presented in the form of graphs and charts to cover a range of mass flow rates with inlet guide vane settings varying from minus 15 degrees to plus 45 degrees. The static pressure distributions in the compressor inlet section and on the impeller and exit diffuser vanes, as well as the overall pressure and temperature rise and mass flow rate, were measured and analyzed at each operating point to determine the overall performance as well as the detailed aerodynamics throughout the compressor.

  7. Role of sampling times and serum cortisol cut-off concentrations on the routine assessment of adrenal function using the standard cosyntropin test in an academic hospital from Spain: a retrospective chart review.

    PubMed

    Ortiz-Flores, Andrés E; Santacruz, Elisa; Jiménez-Mendiguchia, Lucía; García-Cano, Ana; Nattero-Chávez, Lia; Escobar-Morreale, Héctor F; Luque-Ramírez, Manuel

    2018-05-05

    Aiming to validate the use of a single poststimulus sampling protocol for cosyntropin test short standard high-dose test (SST) in our institution, our primary objectives were (1) to determine the concordance between 30 and 60 min serum cortisol (SC) measurements during SST; and (2) to evaluate the diagnostic agreement between both sampling times when using classic or assay-specific and sex-specific SC cut-off values. The secondary objectives included (1) estimating the specificity and positive predictive value of 30 and 60 min sampling times while considering the suspected origin of adrenal insufficiency (AI); and (2) obtaining assay-specific cut-off values for SC after SST in a group of subjects with normal hypothalamic-pituitary-adrenal (HPA) axis. This is a retrospective chart review study conducted at a Spanish academic hospital from 2011 to 2015. Two groups were evaluated: (1) a main study group including 370 patients in whom SC was measured at 30 and 60 min during SST; and (2) a confirmative group that included 150 women presenting with a normal HPA axis in whom SST was conducted to rule out late-onset congenital adrenal hyperplasia. Diagnostic agreement between both sampling times was assessed by considering both classic (500 nmol/L) and assay-specific SC cut-off concentrations. Diagnostic agreement between both sampling times was greater when applying sex-specific and assay-specific cut-off values instead of the classic cut-off values. For suspected primary AI, 30 min SC determination was enough to establish a diagnosis in over 95% of cases, without missing any necessary treatment. When central AI is suspected, 60 min SC measurement was more specific, establishing a diagnosis in over 97% of cases. Sex-specific and assay-specific SC cut-off values improve the diagnostic accuracy of SST. For primary disease, a subnormal SC response at 30 min is a reliable marker of adrenal dysfunction. On the contrary, when central AI is suspected, 60 min SC measurement improves the diagnostic accuracy of the test. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  8. Positive and negative life events and personality traits in predicting course of depression and anxiety.

    PubMed

    Spinhoven, P; Elzinga, B M; Hovens, J G F M; Roelofs, K; van Oppen, P; Zitman, F G; Penninx, B W J H

    2011-12-01

    To examine the prognostic value of personality dimensions and negative and positive life events for diagnostic and symptom course trajectories in depressive and anxiety disorder. A total of 1209 subjects (18-65 years) with depressive and/or anxiety disorder were recruited in primary and specialized mental health care. Personality dimensions at baseline were assessed with the NEO-FFI and incidence and date of life events retrospectively with a structured interview at 2-year follow-up. DSM-IV-based diagnostic interviews as well as life chart assessments allowed course assessment at both the diagnostic and symptom trajectory level over 2 years. Life events were significantly related to diagnostic and symptom course trajectories of depression and anxiety also after correcting for sociodemographic and clinical characteristics. Only negative life events prospectively predicted longer time to remission of depressive disorder. Prospective associations of neuroticism and extraversion with prognosis of anxiety and depression were greatly reduced after correcting for baseline severity and duration of index disorder. Personality traits did not moderate the effect of life events on 2-year course indicators. Negative life events have an independent effect on diagnostic and symptom course trajectories of depression and to a lesser extent anxiety unconfounded by sociodemographic, clinical, and personality characteristics. © 2011 John Wiley & Sons A/S.

  9. Optical Diagnostics for Flow Control on Small Wings

    DTIC Science & Technology

    2016-07-13

    AFRL-AFOSR-VA-TR-2016-0250 Optical diagnostics for flow control on small wings GEOFF SPEDDING UNIVERSITY OF SOUTHERN CALIFORNIA LOS ANGELES...Control on Small Wings 5a. CONTRACT NUMBER 5b. GRANT NUMBER FA9550-15-1-0255 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Geoffrey R Spedding 5d. PROJECT...Nd:YAG laser has been purchased, installed, and heavily-used in essential work. Two most recent investigations concern the flow over a complex wing

  10. The effect of general anesthesia versus intravenous sedation on diagnostic yield and success in electromagnetic navigation bronchoscopy.

    PubMed

    Bowling, Mark R; Kohan, Matthew W; Walker, Paul; Efird, Jimmy; Ben Or, Sharon

    2015-01-01

    Navigational bronchoscopy is utilized to guide biopsies of peripheral lung nodules and place fiducial markers for treatment of limited stage lung cancer with stereotactic body radiotherapy. The type of sedation used for this procedure remains controversial. We performed a retrospective chart review to evaluate the differences of diagnostic yield and overall success of the procedure based on anesthesia type. Electromagnetic navigational bronchoscopy was performed using the superDimension software system. Once the targeted lesion was within reach, multiple tissue samples were obtained. Statistical analysis was used to correlate the yield with the type of sedation among other factors. A successful procedure was defined if a diagnosis was made or a fiducial marker was adequately placed. Navigational bronchoscopy was performed on a total of 120 targeted lesions. The overall complication rate of the procedure was 4.1%. The diagnostic yield and success of the procedure was 74% and 87%, respectively. Duration of the procedure was the only significant difference between the general anesthesia and IV sedation groups (mean, 58 vs. 43 min, P=0.0005). A larger tumor size was associated with a higher diagnostic yield (P=0.032). All other variables in terms of effect on diagnostic yield and an unsuccessful procedure did not meet statistical significance. Navigational bronchoscopy is a safe and effective pulmonary diagnostic tool with relatively low complication rate. The diagnostic yield and overall success of the procedure does not seem to be affected by the type of sedation used.

  11. Identification of a Genomic Signature Predicting for Recurrence in Early Stage Ovarian Cancer

    DTIC Science & Technology

    2014-10-01

    55 Fruit St Boston, MA 02114-2554 9. SPONSORING / MONITORING AGENCY NAME(S) AND ADDRESS(ES) 10. SPONSOR/MONITOR’S ACRONYM(S) U.S. Army Medical...Sections were then dehydrated in 100% EtOH and air-dried before macro- dissection using a sterile, RNase-free scalpel. Figure 2. Flow-chart of

  12. Basic Electricity/Electronics (Industrial Arts). Vocational Education Curriculum Guide. Bulletin 1724.

    ERIC Educational Resources Information Center

    Louisiana State Dept. of Education, Baton Rouge. Div. of Vocational Education.

    This curriculum guide is designed to assist industrial arts teachers, counselors, and administrators in improving instruction in the areas of electricity and basic electronics. Included in the first part of the guide are a course flow chart, a course description, a discussion of target grade levels and prerequisites, course goals and objectives,…

  13. Return to the red planet: The Mars Observer Mission

    NASA Technical Reports Server (NTRS)

    French, Bevan M.; Young, Carolynn (Editor)

    1993-01-01

    An overview of the Mars Observer Mission is discussed. Highlights include: (1) the spacecraft; (2) the instrumentation and science experiments; (3) the countries involved; (4) the flight teams; and (5) the planet Mars itself (a brief history). Photographs and flow charts are included, along with diagrams of instrumentation and a brief historical narrative of space observation and exploration.

  14. Improving The Prototyping Process In Department Of Defense Acquisition

    DTIC Science & Technology

    2014-06-01

    System Flow Chart ................................................. 39 Figure 13. TRL Definitions (from ASD [R&E] 2011... ASD (R&E) Assistant Secretary of Defense for Research and Engineering BCL Business Capability Life cycle CDD Capability Development Document CDR...TRL 6 cannot be attained until the technology has been demonstrated in a relevant operational environment ( ASD [R&E] 2011). A technology that has

  15. Operation Prime Program (Central Junior High School), Title I Evaluation, 1973-76.

    ERIC Educational Resources Information Center

    Granite School District, Salt Lake City, UT.

    This document consists of reports (for the 1973-1974, 1974-1975, and 1975-1976 school years) of an individualized reading and math program designed for secondary school students functioning below their grade level. The program involves a management system using flow charts, independent study, student motivation provided by free time in a…

  16. Pennsylvania Environmental Education Master Plan. New Direction Across the State... ...For the Total Community.

    ERIC Educational Resources Information Center

    Pennsylvania State Dept. of Environmental Resources, Harrisburg.

    This document is Pennsylvania's master plan for environmental education (EE). It includes: (1) a list of planning principles and guidelines to enhance implementation of the master plan; (2) a flow chart illustrating feasibility, planning, action, and impact phases for the years 1983-85; (3) a summary of major recommendations; (4) a chart…

  17. Section I: Basic Electricity. Syllabus in Trade Electricity-Electronics.

    ERIC Educational Resources Information Center

    New York State Education Dept., Albany. Bureau of Occupational and Career Curriculum Development.

    This section describes the first of a three part curriculum in trade electricity-electronics (each part is described in a separate volume). It presents a unit of 6 to 10 weeks duration which develops only those competencies necessary to all electricity or electronics employment. A flow chart indicates how an individual student's program can be…

  18. Compliance Timeline, Compliance Options, and Required Notifications for Surface Coating of Wood Building Products National Emission Standards for Hazardous Air Pollutants (NESHAP)

    EPA Pesticide Factsheets

    This January 2005 document contains a diagram of dates and events for compliance with the NESHAP for surface coating of wood building products. Also on this page is a January 2005 document with flow charts to demonstrate compliance options for the NESHAP

  19. Planning for Schools of Choice: Achieving Equity and Excellence. Book II--Planning Guide.

    ERIC Educational Resources Information Center

    Clinchy, Evans; Kolb, Frances Arick, Ed.

    Designed to aid school personnel considering school choice as a possible desegregation method, this booklet explains the principles of controlled choice, presents an overall plan and flow chart, and reviews the types of organizations that might be developed. Controlled choice is a desegregation method that is voluntary, empowers parents and school…

  20. Analysis of a Digital Technique for Frequency Transposition of Speech.

    DTIC Science & Technology

    1985-09-01

    scaled excitation function drives the vocal tract model. In a phone interview with James Kaiser of Bell Laboratories, he mentioned that current thinking...is processed using the Fast Fourier Transform (FFT) and then low pass filtered if desired. mAbe (Pb) FFT LPF- nih ~a s5ee.. S. 4Nrf#Nr Flow Chart for

  1. Mathematics for the Technical Student: The Use of the Computer in the Systems Approach to Instruction.

    ERIC Educational Resources Information Center

    Capps, Joan P.

    An instructional method using flow-chart symbols to make mathematical abstractions more concrete was implemented for a year in a technical mathematics course. Students received instruction in computer applications and programming in the BASIC language in order to increase motivation and firm the mathematical skills and problem-solving approaches…

  2. Automated Program Recognition by Graph Parsing

    DTIC Science & Technology

    1992-07-01

    structures (cliches) in a program can help an experienced programmer understand the program. Based on the known relationships between the clichis, a...Graph Parsing Linda Mary Wills Abstract The recognition of standard computational structures (cliches) in a program can help an experienced programmer...3.4.1 Structure -Sharing ....... ............................ 76 3.4.2 Aggregation ....................................... 80 2 3.5 Chart Parsing Flow

  3. Statistical Measures, Hypotheses, and Tests in Applied Research

    ERIC Educational Resources Information Center

    Saville, David J.; Rowarth, Jacqueline S.

    2008-01-01

    This article reviews and discusses the use of statistical concepts in a natural resources and life sciences journal on the basis of a census of the articles published in a recent issue of the "Agronomy Journal" and presents a flow chart and a graph that display the inter-relationships between the most commonly used statistical terms. It also…

  4. Identifying, Tracking, and Prioritizing Parts Unavailability

    DTIC Science & Technology

    2013-03-01

    of RFM with MRP Equivalents in Parentheses ................ 13 Figure 2. Flow Chart of Repair Process...by the Air Force is the Reparability Forecast Model (RFM). The RFM operates similar to a Material Requirements Planning ( MRP ) system, where it...Outputs of RFM with MRP Equivalents in Parentheses (Gaudette et al, 2002: 7) The Reparability Forecast Model does not determine stock levels or

  5. Calculus: A Computer Oriented Presentation, Part 1 [and] Part 2.

    ERIC Educational Resources Information Center

    Stenberg, Warren; Walker, Robert J.

    Parts one and two of a one-year computer-oriented calculus course (without analytic geometry) are presented. The ideas of calculus are introduced and motivated through computer (i.e., algorithmic) concepts. An introduction to computing via algorithms and a simple flow chart language allows the book to be self-contained, except that material on…

  6. Orbital transfer vehicle studies overview

    NASA Technical Reports Server (NTRS)

    Perkinson, Don

    1987-01-01

    An overview is given in viewgraph form of orbital transfer vehicle concept definition and systems analysis studies. Project development flow charts are shown for key milestones from 1985 until 1997. Diagrams of vehicles are given. Information is presented in outline form on technology requirements, cooling of propellant tanks, cryogenic fluid management, quick connect/disconnect fluid interfaces and propellant mass transfer.

  7. JPRS Report, Science & Technology, China, 16th International Congress of the International Society for Photogrammetry and Remote Sensing -- Vol. 1

    DTIC Science & Technology

    1989-01-26

    introduction, review and prospects." AUTOCARTO 8 pp 510-519. [VOY 10] VOYER: " Moteurs de systemes experts." Eyrolles editions 61, Bd. St.-Germain 75005...each knowlege Output of Extrated Results Oceanic Conditions Extraction Meta -Rule Base Figure 3. General Flow Chart of the System 207

  8. Skylab S-191 spectrometer single spectral scan analysis program. [user manual

    NASA Technical Reports Server (NTRS)

    Downes, E. L.

    1974-01-01

    Documentation and user information for the S-191 single spectral scan analysis program are reported. A breakdown of the computational algorithms is supplied, followed by the program listing and examples of sample output. A copy of the flow chart which describes the driver routine in the body of the main program segment is included.

  9. Mapping individual logical processes in information searching

    NASA Technical Reports Server (NTRS)

    Smetana, F. O.

    1974-01-01

    An interactive dialog with a computerized information collection was recorded and plotted in the form of a flow chart. The process permits one to identify the logical processes employed in considerable detail and is therefore suggested as a tool for measuring individual thought processes in a variety of situations. A sample of an actual test case is given.

  10. Power/Energy (Industrial Arts). Vocational Education Curriculum Guide. Bulletin 1723.

    ERIC Educational Resources Information Center

    Louisiana State Dept. of Education, Baton Rouge. Div. of Vocational Education.

    This curriculum guide is designed to assist industrial arts practitioners in improving instruction in the areas of energy and power technology. Included in the first part of the guide are a course flow chart, a course description, a discussion of target grade levels and prerequisites, course goals and objectives, an introduction, and a course…

  11. College Achievement Through Self-Help. A Planning and Guidance Manual For Minority Students.

    ERIC Educational Resources Information Center

    Nieves, Luis

    In this manual for minority students in higher education, advice is provided on the following topics: (1) methods of self personality assessment, including lists, questions, and flow charts; (2) suggestions for budgeting study time in an individual schedule; (3) relaxation techniques to combat anxiety; (4) methods of self-management in cases of…

  12. New York State Educational Information System (NYSEIS) Systems Design. Volume I, Phase II. Final Report.

    ERIC Educational Resources Information Center

    Price Waterhouse and Co., New York, NY.

    This volume on Phase II of the New York State Educational Information System (NYSEIS) describes the Gross Systems Analysis and Design, which includes the general flow diagram and processing chart for each of the student, personnel, and financial subsystems. Volume II, Functional Specifications, includes input/output requirements and file…

  13. A Classroom Note on: Modeling Functions with the TI-83/84 Calculator

    ERIC Educational Resources Information Center

    Lubowsky, Jack

    2011-01-01

    In Pre-Calculus courses, students are taught the composition and combination of functions to model physical applications. However, when combining two or more functions into a single more complicated one, students may lose sight of the physical picture which they are attempting to model. A block diagram, or flow chart, in which each block…

  14. Teaching Inferential Statistics to Social Work Students: A Decision-Making Flow Chart

    ERIC Educational Resources Information Center

    Calderwood, Kimberly A.

    2012-01-01

    Given that social work research courses are typically built on modernist principles of teaching and content, it is not surprising that the majority of social work students dread these courses. Few attempts have been made to better align the modernist content of quantitative research with the postmodern philosophy and values inherent in current…

  15. Treatment of breast cancer patients from a public healthcare system in a private center: costs of care for a pilot public-private partnership in oncology

    PubMed Central

    Kaliks, Rafael Aliosha; Pontes, Lucíola de Barros; Bognar, Cinthia Leite Frizzera Borges; Santos, Kelly Cristine Carvalho; Bromberg, Sílvio Eduardo; do Amaral, Paulo Gustavo Tenório; Karnakis, Theodora; Chen, Michael; de Andrade, Cláudia Toledo; Dantas, Joacira; Escobosa, Daísa de Mesquita; Giglio, Auro Del

    2013-01-01

    ABSTRACT Objective: To describe the flow and costs associated with the diagnosis and treatment of patients with breast cancer who come from the public healthcare system and were treated at Hospital Israelita Albert Einstein. Methods: Between August 2009, and December 2011, 51 patients referred by the Unified Public Healthcare System (SUS) had access to Hospital Israelita Albert Einstein for diagnostic radiology, medical oncology, radiotherapy, and oncologic/ breast reconstruction surgery. The data were collected retrospectively from the hospital records, patient charts, pharmacy records, and from the hospital billing system. Results: The total sum spent for diagnosis and treatment of these 51 patients was US$ 1,457,500.00. This value encompassed expenses with a total of 85 hospitalizations, 2,875 outpatient visits, 16 emergency room visits, and all expenses associated with these stays at the hospital. The expenditure for treatment of each patient submitted to biopsy, breast conserving surgery, adjuvant chemotherapy without trastuzumab (a regime with taxane followed by anthracycline), radiotherapy, and 5 years of tamoxifen was approximately US$ 25,500.00. Conclusion: Strategies for cost-reduction of treatment in the private setting are necessary to enable future large-scale public-private partnerships in oncology. PMID:23843064

  16. Central precocious puberty: from physiopathological mechanisms to treatment.

    PubMed

    Chirico, V; Lacquaniti, A; Salpietro, V; Buemi, M; Salpietro, C; Arrigo, T

    2014-01-01

    Puberty is a complex, coordinated biological process with multiple levels of regulations. The timing of puberty varies greatly in children and it is influenced by environmental, endocrine and genetic factors. Precocious puberty (PP) is an important issue, affecting between 1 in 5.000-10.000 children. The physiopathological mechanism is still unknown. From an etiological point of view, PP may be subdivided into gonadotropin-releasing hormone (GnRH) -dependent and independent causes. GnRH-dependent PP, often called central precocious puberty (CPP), is based on hypothalamic-pituitary-gonadal axis activation associated with progressive pubertal development, accelerated growth rate and advancement of skeletal age. Conversely, peripheral precocious puberty (PPP) is related to sex steroid exposure, independently of hypothalamic-–pituitary-–gonadal (HPG) axis activation. Kisspeptins play a central role in the modulation of GnRH secretion with peripheral factors that influence the timing of puberty, such as adipokines and endocrine disrupting chemicals. Moreover, PP could be related to genetic disorders, involving pivotal genes of the HPG axis. The standard test used to verify HPG activity is the gonadotropin response to administered GnRH analogs. We describe the physiopathological mechanisms of PP and its clinical implications, analysing diagnostic flow-chart and new potential biomarkers that could reveal PP. An update of the current literature was also carried out regarding the recent novelty for treatment.

  17. Validation of an Electronic System for Recording Medical Student Patient Encounters

    PubMed Central

    Nkoy, Flory L.; Petersen, Sarah; Matheny Antommaria, Armand H.; Maloney, Christopher G.

    2008-01-01

    The Liaison Committee for Medical Education requires monitoring of the students’ clinical experiences. Student logs, typically used for this purpose, have a number of limitations. We used an electronic system called Patient Tracker to passively generate student encounter data. The data contained in Patient Tracker was compared to the information reported on student logs and data abstracted from the patients’ charts. Patient Tracker identified 30% more encounters than the student logs. Compared to the student logs, Patient Tracker contained a higher average number of diagnoses per encounter (2.28 vs. 1.03, p<0.01). The diagnostic data contained in Patient Tracker was also more accurate under 4 different definitions of accuracy. Only 1.3% (9/677) of diagnoses in Patient Tracker vs. 16.9% (102/601) diagnoses in the logs could not be validated in patients’ charts (p<0.01). Patient Tracker is a more effective and accurate tool for documenting student clinical encounters than the conventional student logs. PMID:18999155

  18. Resource utilization in children with tuberous sclerosis complex and associated seizures: a retrospective chart review study.

    PubMed

    Lennert, Barb; Farrelly, Eileen; Sacco, Patricia; Pira, Geraldine; Frost, Michael

    2013-04-01

    Seizures are a hallmark manifestation of tuberous sclerosis complex, yet data characterizing resource utilization are lacking. This retrospective chart review was performed to assess the economic burden of tuberous sclerosis complex with neurologic manifestations. Demographic and resource utilization data were collected for 95 patients for up to 5 years after tuberous sclerosis complex diagnosis. Mean age at diagnosis was 3.1 years, with complex partial and infantile spasms as the most common seizure types. In the first 5 years post-diagnosis, 83.2% required hospitalization, 30.5% underwent surgery, and the majority of patients (90.5%) underwent ≥3 testing procedures. In 79 patients with a full 5 years of data, hospitalizations, intensive care unit stays, diagnostic testing, and rehabilitation services decreased over the 5-year period. Resource utilization is cost-intensive in children with tuberous sclerosis complex and associated seizures during the first few years following diagnosis. Improving seizure control and reducing health care costs in this population remain unmet needs.

  19. Integration of platinum nanoparticles with a volumetric bar-chart chip for biomarker assays.

    PubMed

    Song, Yujun; Xia, Xuefeng; Wu, Xifeng; Wang, Ping; Qin, Lidong

    2014-11-10

    Platinum nanoparticles (PtNPs) efficiently catalyze the transformation of H2 O2 into oxygen gas. However, owing to the lack of an efficient approach or device that can measure the produced oxygen gas, the catalytic reaction has never been used for diagnostic applications. Microfluidics technology provides a platform that meets these requirements. The volumetric bar-chart chip (V-Chip) volumetrically measures the production of oxygen gas by PtNPs and can be integrated with ELISA technology to provide visible and quantitative readouts without expensive instrumentation or complicated data processing. Herein we show that PtNPs outperform catalase with respect to stability at high H2 O2 concentrations or temperatures or in long-term reactions, and are resistant to most catalase inhibitors. We also show that the catalase-like activity of PtNPs can be used in combination with the V-Chip to sensitively and specifically detect cancer biomarkers both in serum and on the cell surface. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  20. A versatile quantitation platform based on platinum nanoparticles incorporated volumetric bar-chart chip for highly sensitive assays.

    PubMed

    Wang, Yuzhen; Zhu, Guixian; Qi, Wenjin; Li, Ying; Song, Yujun

    2016-11-15

    Platinum nanoparticles incorporated volumetric bar-chart chip (PtNPs-V-Chip) is able to be used for point-of-care tests by providing quantitative and visualized readout without any assistance from instruments, data processing, or graphic plotting. To improve the sensitivity of PtNPs-V-Chip, hybridization chain reaction was employed in this quantitation platform for highly sensitive assays that can detect as low as 16 pM Ebola Virus DNA, 0.01ng/mL carcinoembryonic antigen (CEA), and the 10 HER2-expressing cancer cells. Based on this amplified strategy, a 100-fold decrease of detection limit was achieved for DNA by improving the number of platinum nanoparticle catalyst for the captured analyte. This quantitation platform can also distinguish single base mismatch of DNA hybridization and observe the concentration threshold of CEA. The new strategy lays the foundation for this quantitation platform to be applied in forensic analysis, biothreat detection, clinical diagnostics and drug screening. Copyright © 2016 Elsevier B.V. All rights reserved.

  1. Aerodynamic Design of Axial-flow Compressors. Volume III

    NASA Technical Reports Server (NTRS)

    Johnson, Irving A; Bullock, Robert O; Graham, Robert W; Costilow, Eleanor L; Huppert, Merle C; Benser, William A; Herzig, Howard Z; Hansen, Arthur G; Jackson, Robert J; Yohner, Peggy L; hide

    1956-01-01

    Chapters XI to XIII concern the unsteady compressor operation arising when compressor blade elements stall. The fields of compressor stall and surge are reviewed in Chapters XI and XII, respectively. The part-speed operating problem in high-pressure-ratio multistage axial-flow compressors is analyzed in Chapter XIII. Chapter XIV summarizes design methods and theories that extend beyond the simplified two-dimensional approach used previously in the report. Chapter XV extends this three-dimensional treatment by summarizing the literature on secondary flows and boundary layer effects. Charts for determining the effects of errors in design parameters and experimental measurements on compressor performance are given in Chapters XVI. Chapter XVII reviews existing literature on compressor and turbine matching techniques.

  2. Does the Alpha-defensin Immunoassay or the Lateral Flow Test Have Better Diagnostic Value for Periprosthetic Joint Infection? A Systematic Review.

    PubMed

    Eriksson, Hannah K; Nordström, Jakob; Gabrysch, Katja; Hailer, Nils P; Lazarinis, Stergios

    2018-05-01

    Measuring alpha-defensin concentrations in synovial fluid may help to diagnose periprosthetic joint infection (PJI). There are two commercially available methods for measuring alpha-defensin in synovial fluid: the enzyme-linked immunosorbent assay-based Synovasure® alpha-defensin immunoassay, which gives a numeric readout within 24 hours, and the Synovasure lateral flow test, which gives a binary readout within 20 minutes. There is no compilation of the existing literature to support the use of one of these two tests over the other. Does the immunoassay or the lateral flow test have better diagnostic value (sensitivity and specificity) in diagnosing PJI? We followed PRISMA guidelines and identified all studies on alpha-defensin concentration in synovial fluid as a PJI diagnostic marker, indexed to April 14, 2017, in PubMed, JSTOR, Google Scholar, and OVID databases. The search retrieved 1578 records. All prospective and retrospective studies on alpha-defensin as a PJI marker (PJI classified according to the criteria of the Musculoskeletal Infection Society) after THA or TKA were included in the analysis. All studies used only one of the two commercially available test methods, but none of them was comparative. After excluding studies with overlapping patient populations, four studies investigating the alpha-defensin immunoassay and three investigating the lateral flow test remained. Alpha-defensin immunoassay studies included 482 joints and lateral flow test studies included 119. The quality of the trials was assessed according to the Quality Assessment of Diagnostic Accuracy Studies (QUADAS-2) tool. The heterogeneity among studies was evaluated by the I index, indicating that the heterogeneity of the included studies was low. Pooled sensitivity, specificity, positive and negative likelihood ratios, and receiver operating curves were calculated for each method and compared with each other. The alpha-defensin immunoassay had superior overall diagnostic value compared with the lateral flow test (area under the curve, 0.98 versus 0.75) with higher sensitivity (96% [90%-98%] versus 71% [55%-83%], p < 0.001), but no difference in specificity with the numbers available (96% [93%-97%] versus 90% [81%-95%], p = 0.060). Measurement of alpha-defensin in synovial fluid is a valuable complement to existing diagnostic criteria, and the immunoassay test detects PJI more accurately than the lateral flow test. The lateral flow test has lower sensitivity, making it difficult to rule out infection, but its relatively high specificity combined with the advantage of a quick response time can make it useful to rule in infection perioperatively. Level III, diagnostic study.

  3. Diagnostic blood-flow monitoring during therapeutic interventions using color Doppler optical coherence tomography

    NASA Astrophysics Data System (ADS)

    Yazdanfar, Siavash; Kulkarni, Manish D.; Wong, Richard C. K.; Sivak, Michael J., Jr.; Willis, Joseph; Barton, Jennifer K.; Welch, Ashley J.; Izatt, Joseph A.

    1998-04-01

    A recently developed modality for blood flow measurement holds high promise in the management of bleeding ulcers. Color Doppler optical coherence tomography (CDOCT) uses low- coherence interferometry and digital signal processing to obtain precise localization of tissue microstructure simultaneous with bi-directional quantitation of blood flow. We discuss CDOCT as a diagnostic tool in the management of bleeding gastrointestinal lesions. Common treatments for bleeding ulcers include local injection of a vasoconstrictor, coagulation of blood via thermal contact or laser treatment, and necrosis of surrounding tissue with a sclerosant. We implemented these procedures in a rat dorsal skin flap model, and acquired CDOCT images before and after treatment. In these studies, CDOCT succeeded in identifying cessation of flow before it could be determined visually. Hence, we demonstrate the diagnostic capabilities of CDOCT in the regulation of bleeding in micron-scale vessels.

  4. Effects of cigarette smoking on diagnostic tests for work-related hypersensitivity pneumonitis: data from an outbreak of lung disease in metalworkers.

    PubMed

    Dangman, Kenneth H; Storey, Eileen; Schenck, Paula; Hodgson, Michael J

    2004-05-01

    It is widely believed that development of hypersensitivity pneumonitis (HP) is forestalled in cigarette smokers. We encountered the largest outbreak of HP in metalworkers yet reported [Hodgson et al. (2001): Am J Ind Med 39:616-628] and subsequently did a chart review of the 61 patients seen in connection with the outbreak [Dangman et al. (2002a): Am J Resp Crit Care Med 165(8):A528; Dangman et al. (2002b): Am J Ind Med 42:150-162], developing a diagnostic index for this disease. A re-examination of data from the chart review was carried out to explore possible effects of cigarette smoking on the clinical tests used to diagnose HP [Hodgson et al. (2001): Am J Ind Med 39:616-628]. Cigarette smokers with HP were less likely than non-smokers with HP to develop crackles in the lungs, elevated erythrocyte sedimentation rates (ESRs), and restrictive spirometry. Smoking habits had little effect on diffusion capacity and alveolar-arterial oxygen gradients in the patients with HP. Smokers were more likely to have abnormal gallium scans than non-smokers. It appears that cigarette smoking can affect the physical examination findings, spirometry, and ESR changes associated with HP, making these tests less sensitive and specific, and potentially obscuring the diagnosis. Such changes may contribute to the apparent "protective" effect of smoking on the development of HP.

  5. Colorectal cancer screening in patients with spinal cord injury yields similar results to the general population with an effective bowel preparation: a retrospective chart audit.

    PubMed

    Teng, Brandon J; Song, Shawn H; Svircev, Jelena N; Dominitz, Jason A; Burns, Stephen P

    2018-03-01

    Retrospective chart audit. To compare adequacy of colonoscopy bowel preparation and diagnostic findings between persons with SCI receiving an extended inpatient bowel preparation and the general population. Veterans Affairs Puget Sound Healthcare System, Seattle, WA, USA. We reviewed an electronic database of all colonoscopies performed at a tertiary Veterans Affairs medical center between 7/12/13 and 15/10/15. Patients with SCI received a multi-day bowel preparation with magnesium citrate, and 8-10 liters of polyethylene glycol-3350 and electrolyte colonic lavage solution (PEG-ELS) over two and one half days. The control population received a standard bowel preparation consisting of magnesium citrate and 4 liters of PEG-ELS over 1 day. Two hundred and fifty-five patients were included in the study, including 85 patients with SCI. Average risk screening was a more common colonoscopy indication in patients with SCI vs. the control population (24 vs. 13% p = 0.03). There was no difference in adequacy of bowel preparation (87 vs. 85%, p = 0.73) or adenoma detection rate (55 vs. 51%, p = 0.59) when comparing patients with SCI with the control population. No difference in polyp histopathology was detected (p = 0.748). Our study demonstrated that an extended bowel preparation for patients with SCI produces similar bowel preparation results and diagnostic yield when compared to patients without SCI undergoing colonoscopy.

  6. The prevalence of depressive symptoms in frontotemporal dementia: a meta-analysis.

    PubMed

    Chakrabarty, Trisha; Sepehry, Amir A; Jacova, Claudia; Hsiung, Ging-Yuek Robin

    2015-01-01

    Depression is common in Alzheimer's and vascular dementia and is associated with poorer outcomes; however, less is known about the impact of depression on frontotemporal dementia (FTD). Here, we conducted a meta-analysis of diagnostic methods and the prevalence of depressive symptoms in FTD. PubMed, EMBASE and PsychINFO were queried for 'depression' and/or 'depressive mood' in behavioral- and language-variant FTD. The prevalence and diagnosis of depressive symptoms were extracted from relevant studies and the results pooled using a random-effects model. We included 29 studies in this meta-analysis, with sample sizes ranging from 3 to 73 (n = 870). The omnibus estimated event rate of depressed mood was 0.334 (33%; 95% CI: 0.268-0.407). Symptoms were most commonly assessed via standardized neuropsychiatric rating scales, with other methods including subjective caregiver reports and chart reviews. The study results were heterogeneous due to the variability in diagnostic methods. Depressive symptoms similar to those in other dementias are commonly detected in FTD. However, the diagnostic methods are heterogeneous, and symptoms of depression often overlap with manifestations of FTD. Having a standardized diagnostic approach to depression in FTD will greatly facilitate future research in this area.

  7. Endobronchial Ultrasound-guided Transbronchial Needle Aspiration Using 19-G Needle for Sarcoidosis.

    PubMed

    Balwan, Akshu

    2018-05-16

    Flexible bronchoscopy with endobronchial ultrasound (EBUS)-guided transbronchial needle aspiration (TBNA) is increasingly being used to obtain pathology specimens for diagnosis of sarcoidosis. There is wide variation in reported diagnostic yield in literature. New TBNA needles are available in the market but data are lacking about their diagnostic yield especially for sarcoidosis. This study reports the diagnostic yield of bronchoscopy with EBUS-TBNA using ViziShot FLEX 19-G needle in a series of patients with suspected sarcoidosis. This is a retrospective chart review for diagnostic yield of the 19-G EBUS-TBNA needle for suspected sarcoidosis. Eighty-six EBUS bronchoscopies were performed, 15 were done with clinical suspicion of sarcoidosis. The 19-G needle was used for all cases of suspected sarcoidosis. The procedure was diagnostic of sarcoidosis in 14 (93.3%) patients by TBNA with 1 nondiagnostic bronchoscopy. Procedural diagnostic yield was 93.3%. Eighty-five percent (28/33) of sampled lymph nodes were positive for noncaseating granulomas. The yield of transbronchial lung biopsy (TBLB) and endobronchial lung biopsy was 38% (5/13) and 43% (6/14), respectively. TBLB and endobronchial lung biopsy did not add to the diagnostic yield of the procedure. No significant adverse events were noted. This series reports a higher diagnostic yield than most other published studies and opens platform for direct comparison of each available needle. It also adds to the safety data for this larger needle. In addition, it raises doubt into utility of TBLB for diagnosis of sarcoidosis, which can increase the procedural complications.

  8. A spectral chart method for estimating the mean turbulent kinetic energy dissipation rate

    NASA Astrophysics Data System (ADS)

    Djenidi, L.; Antonia, R. A.

    2012-10-01

    We present an empirical but simple and practical spectral chart method for determining the mean turbulent kinetic energy dissipation rate < \\varepsilon rangle in a variety of turbulent flows. The method relies on the validity of the first similarity hypothesis of Kolmogorov (C R (Doklady) Acad Sci R R SS, NS 30:301-305, 1941) (or K41) which implies that spectra of velocity fluctuations scale on the kinematic viscosity ν and < \\varepsilon rangle at large Reynolds numbers. However, the evidence, based on the DNS spectra, points to this scaling being also valid at small Reynolds numbers, provided effects due to inhomogeneities in the flow are negligible. The methods avoid the difficulty associated with estimating time or spatial derivatives of the velocity fluctuations. It also avoids using the second hypothesis of K41, which implies the existence of a -5/3 inertial subrange only when the Taylor microscale Reynods number R λ is sufficiently large. The method is in fact applied to the lower wavenumber end of the dissipative range thus avoiding most of the problems due to inadequate spatial resolution of the velocity sensors and noise associated with the higher wavenumber end of this range.The use of spectral data (30 ≤ R λ ≤ 400) in both passive and active grid turbulence, a turbulent mixing layer and the turbulent wake of a circular cylinder indicates that the method is robust and should lead to reliable estimates of < \\varepsilon rangle in flows or flow regions where the first similarity hypothesis should hold; this would exclude, for example, the region near a wall.

  9. FlowSOM: Using self-organizing maps for visualization and interpretation of cytometry data.

    PubMed

    Van Gassen, Sofie; Callebaut, Britt; Van Helden, Mary J; Lambrecht, Bart N; Demeester, Piet; Dhaene, Tom; Saeys, Yvan

    2015-07-01

    The number of markers measured in both flow and mass cytometry keeps increasing steadily. Although this provides a wealth of information, it becomes infeasible to analyze these datasets manually. When using 2D scatter plots, the number of possible plots increases exponentially with the number of markers and therefore, relevant information that is present in the data might be missed. In this article, we introduce a new visualization technique, called FlowSOM, which analyzes Flow or mass cytometry data using a Self-Organizing Map. Using a two-level clustering and star charts, our algorithm helps to obtain a clear overview of how all markers are behaving on all cells, and to detect subsets that might be missed otherwise. R code is available at https://github.com/SofieVG/FlowSOM and will be made available at Bioconductor. © 2015 International Society for Advancement of Cytometry.

  10. International Retrospective Chart Review of Treatment Patterns in Severe Familial Mediterranean Fever, Tumor Necrosis Factor Receptor-Associated Periodic Syndrome, and Mevalonate Kinase Deficiency/Hyperimmunoglobulinemia D Syndrome.

    PubMed

    Ozen, Seza; Kuemmerle-Deschner, Jasmin B; Cimaz, Rolando; Livneh, Avi; Quartier, Pierre; Kone-Paut, Isabelle; Zeft, Andrew; Spalding, Steve; Gul, Ahmet; Hentgen, Veronique; Savic, Sinisa; Foeldvari, Ivan; Frenkel, Joost; Cantarini, Luca; Patel, Dony; Weiss, Jeffrey; Marinsek, Nina; Degun, Ravi; Lomax, Kathleen G; Lachmann, Helen J

    2017-04-01

    Periodic fever syndrome (PFS) conditions are characterized by recurrent attacks of fever and localized inflammation. This study examined the diagnostic pathway and treatments at tertiary centers for familial Mediterranean fever (FMF), tumor necrosis factor receptor-associated periodic syndrome (TRAPS), and mevalonate kinase deficiency (MKD)/hyperimmunoglobulinemia D syndrome (HIDS). PFS specialists at medical centers in the US, the European Union, and the eastern Mediterranean participated in a retrospective chart review, providing de-identified data in an electronic case report form. Patients were treated between 2008 and 2012, with at least 1 year of followup; all had clinical and/or genetically proven disease and were on/eligible for biologic treatment. A total of 134 patients were analyzed: FMF (n = 49), TRAPS (n = 47), and MKD/HIDS (n = 38). Fever was commonly reported as severe across all indications. Other frequently reported severe symptoms were serositis for FMF patients and elevated acute-phase reactants and gastrointestinal upset for TRAPS and MKD/HIDS. A long delay from disease onset to diagnosis was seen within TRAPS and MKD/HIDS (5.8 and 7.1 years, respectively) compared to a 1.8-year delay in FMF patients. An equal proportion of TRAPS patients first received anti-interleukin-1 (anti-IL-1) and anti-tumor necrosis factor (anti-TNF) biologic agents, whereas IL-1 blockade was the main choice for FMF patients resistant to colchicine and MKD/HIDS patients. For TRAPS patients, treatment with anakinra versus anti-TNF treatments as first biologic agent resulted in significantly higher clinical and biochemical responses (P = 0.03 and P < 0.01, respectively). No significant differences in responses were observed between biologic agents among other cohorts. Referral patterns and diagnostic delays highlight the need for greater awareness and improved diagnostics for PFS. This real-world treatment assessment supports the need for further refinement of treatment practices. © 2016, American College of Rheumatology.

  11. An analytical approach to thermal modeling of Bridgman type crystal growth: One dimensional analysis. Computer program users manual

    NASA Technical Reports Server (NTRS)

    Cothran, E. K.

    1982-01-01

    The computer program written in support of one dimensional analytical approach to thermal modeling of Bridgman type crystal growth is presented. The program listing and flow charts are included, along with the complete thermal model. Sample problems include detailed comments on input and output to aid the first time user.

  12. A Study of Acoustic Forcing on Gas Centered Swirl Coaxial Reacting Flows (Conference Paper with Briefing Charts)

    DTIC Science & Technology

    2017-01-09

    intensifier with a Semrock filter (FF01-425/26). The reflective surface of this dichroic mirror rejected the blue light portion from the broadband...chemiluminescence was also imaged using a HiCATT intensifier with a Semrock filter (FF01-320/40). The shadowgraph camera was set to a gate of 7 µs

  13. An Integrated Approach to the Use of Complementary Visual Learning Tools in an Undergraduate Microbiology Class

    ERIC Educational Resources Information Center

    McCabe, Bernadette

    2011-01-01

    The ability to appreciate the inter-connectedness of complex biological relationships can be difficult for many students. Graphical knowledge in the form of concept maps and flow charts are learning tools which can assist students to recognise the inter-connectivity. This report focuses on a trial which incorporates these two related visual…

  14. Digital adaptive controllers for VTOL vehicles. Volume 2: Software documentation

    NASA Technical Reports Server (NTRS)

    Hartmann, G. L.; Stein, G.; Pratt, S. G.

    1979-01-01

    The VTOL approach and landing test (VALT) adaptive software is documented. Two self-adaptive algorithms, one based on an implicit model reference design and the other on an explicit parameter estimation technique were evaluated. The organization of the software, user options, and a nominal set of input data are presented along with a flow chart and program listing of each algorithm.

  15. Study of EPR/ESR Dosimetry in Fingernails as a Method for Assessing Dose of Victims of Radiological Accidents/Incidents

    DTIC Science & Technology

    2008-06-17

    dosimeters . .............................................................................................. 117 Figure 4-2. Flow chart illustrating...alanine, various sugars, quartz in rocks and sulfates, as EPR dosimeters [15]. Alternatively, radiation-induced EPR signals have been detected using...the medical response to radiological accidents, as a method for estimating radiation dose without the use of physical dosimeters and using exposed

  16. Sizing-tube-fin space radiators

    NASA Technical Reports Server (NTRS)

    Peoples, J. A.

    1978-01-01

    Temperature and size considerations of the tube fin space radiator were characterized by charts and equations. An approach of accurately assessing rejection capability commensurate with a phase A/B level output is reviewed. A computer program, based on Mackey's equations, is also presented which sizes the rejection area for a given thermal load. The program also handles the flow and thermal considerations of the film coefficient.

  17. Calculations for interpretation of solar vector magnetograph data. [sunspots - spectrum analysis/data correlation

    NASA Technical Reports Server (NTRS)

    Dunn, A. R.

    1975-01-01

    Computer techniques for data analysis of sunspot observations are presented. Photographic spectra were converted to digital form and analyzed. Methods of determining magnetic field strengths, i.e., the Zeeman effect, are discussed. Errors originating with telescope equipment and the magnetograph are treated. Flow charts of test programs and procedures of the data analysis are shown.

  18. The GLAS Science Algorithm Software (GSAS) Detailed Design Document Version 6. Volume 16

    NASA Technical Reports Server (NTRS)

    Lee, Jeffrey E.

    2013-01-01

    The Geoscience Laser Altimeter System (GLAS) is the primary instrument for the ICESat (Ice, Cloud and Land Elevation Satellite) laser altimetry mission. ICESat was the benchmark Earth Observing System (EOS) mission for measuring ice sheet mass balance, cloud and aerosol heights, as well as land topography and vegetation characteristics. From 2003 to 2009, the ICESat mission provided multi-year elevation data needed to determine ice sheet mass balance as well as cloud property information, especially for stratospheric clouds common over polar areas. It also provided topography and vegetation data around the globe, in addition to the polar-specific coverage over the Greenland and Antarctic ice sheets.This document describes the detailed design of GLAS Science Algorithm Software (GSAS). The GSAS is used to create the ICESat GLAS standard data products. The National Snow and Ice Data Center (NSDIC) distribute these products. The document contains descriptions, flow charts, data flow diagrams, and structure charts for each major component of the GSAS. The purpose of this document is to present the detailed design of the GSAS. It is intended as a reference source to assist the maintenance programmer in making changes that fix or enhance the documented software.

  19. Endodontic-related inferior alveolar nerve injuries: A review and a therapeutic flow chart.

    PubMed

    Castro, R; Guivarc'h, M; Foletti, J M; Catherine, J H; Chossegros, C; Guyot, L

    2018-05-03

    Inferior alveolar nerve (IAN) lesions related to endodontic treatments can be explained by the anatomical proximity between the apices of the mandibular posterior teeth and the mandibular canal. The aim of this article is to review the management of inferior alveolar nerve lesions due to endodontic treatments and to establish a therapeutic flow chart. A review of publications reporting IAN damage related to endodontic treatment over the past 20 years has been conducted, using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses checklist; it combines an electronic search of the Pubmed ® and Google Scholar ® databasis. Forty-two full-text articles corresponding to 115 clinical cases have been selected. Two personal clinical cases were additionally reported. IAN lesions due to endodontic treatments require urgent management. Early surgical removal of the excess of endodontic material, in contact with the nerve allows the best recovery prognosis (72h). Beyond this delay, irreversible nervous lesions prevail and a medical symptomatic treatment, most of the time with pregabalin, must be/can be carried out. A delayed surgical procedure shows some good benefits for patients. However, the healing prognosis remains poorly predictable. Copyright © 2018. Published by Elsevier Masson SAS.

  20. Generically Used Expert Scheduling System (GUESS): User's Guide Version 1.0

    NASA Technical Reports Server (NTRS)

    Liebowitz, Jay; Krishnamurthy, Vijaya; Rodens, Ira

    1996-01-01

    This user's guide contains instructions explaining how to best operate the program GUESS, a generic expert scheduling system. GUESS incorporates several important features for a generic scheduler, including automatic scheduling routines to generate a 'first' schedule for the user, a user interface that includes Gantt charts and enables the human scheduler to manipulate schedules manually, diagnostic report generators, and a variety of scheduling techniques. The current version of GUESS runs on an IBM PC or compatible in the Windows 3.1 or Windows '95 environment.

  1. A 4-cylinder Stirling engine computer program with dynamic energy equations

    NASA Technical Reports Server (NTRS)

    Daniele, C. J.; Lorenzo, C. F.

    1983-01-01

    A computer program for simulating the steady state and transient performance of a four cylinder Stirling engine is presented. The thermodynamic model includes both continuity and energy equations and linear momentum terms (flow resistance). Each working space between the pistons is broken into seven control volumes. Drive dynamics and vehicle load effects are included. The model contains 70 state variables. Also included in the model are piston rod seal leakage effects. The computer program includes a model of a hydrogen supply system, from which hydrogen may be added to the system to accelerate the engine. Flow charts are provided.

  2. Theoretical and Measured Attenuation of Mufflers at Room Temperature Without Flow, with Comments on Engine-exhaust Muffler Design

    NASA Technical Reports Server (NTRS)

    Davis, Don D , Jr; Stevens, George L , Jr; Moore, Dewey; Stokes, George M

    1953-01-01

    Equations are presented for the attenuation characteristics of several types of mufflers. Experimental curves of attenuation plotted against frequency are presented for 77 different mufflers and the results are compared with theory. The experiments were made at room temperature without flow and the sound source was a loud-speaker. A method is given for including the tail pipe in the calculations. The application of the theory to the design of engine-exhaust mufflers is discussed, and charts have been included for the assistance of the designer.

  3. Development and evaluation of virtual refrigerant mass flow sensors for fault detection and diagnostics

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kim, Woohyun; Braun, J.

    Refrigerant mass flow rate is an important measurement for monitoring equipment performance and enabling fault detection and diagnostics. However, a traditional mass flow meter is expensive to purchase and install. A virtual refrigerant mass flow sensor (VRMF) uses a mathematical model to estimate flow rate using low-cost measurements and can potentially be implemented at low cost. This study evaluates three VRMFs for estimating refrigerant mass flow rate. The first model uses a compressor map that relates refrigerant flow rate to measurements of inlet and outlet pressure, and inlet temperature measurements. The second model uses an energy-balance method on the compressormore » that uses a compressor map for power consumption, which is relatively independent of compressor faults that influence mass flow rate. The third model is developed using an empirical correlation for an electronic expansion valve (EEV) based on an orifice equation. The three VRMFs are shown to work well in estimating refrigerant mass flow rate for various systems under fault-free conditions with less than 5% RMS error. Each of the three mass flow rate estimates can be utilized to diagnose and track the following faults: 1) loss of compressor performance, 2) fouled condenser or evaporator filter, 3) faulty expansion device, respectively. For example, a compressor refrigerant flow map model only provides an accurate estimation when the compressor operates normally. When a compressor is not delivering the expected flow due to a leaky suction or discharge valve or other internal fault, the energy-balance or EEV model can provide accurate flow estimates. In this paper, the flow differences provide an indication of loss of compressor performance and can be used for fault detection and diagnostics.« less

  4. Rocket Engine Oscillation Diagnostics

    NASA Technical Reports Server (NTRS)

    Nesman, Tom; Turner, James E. (Technical Monitor)

    2002-01-01

    Rocket engine oscillating data can reveal many physical phenomena ranging from unsteady flow and acoustics to rotordynamics and structural dynamics. Because of this, engine diagnostics based on oscillation data should employ both signal analysis and physical modeling. This paper describes an approach to rocket engine oscillation diagnostics, types of problems encountered, and example problems solved. Determination of design guidelines and environments (or loads) from oscillating phenomena is required during initial stages of rocket engine design, while the additional tasks of health monitoring, incipient failure detection, and anomaly diagnostics occur during engine development and operation. Oscillations in rocket engines are typically related to flow driven acoustics, flow excited structures, or rotational forces. Additional sources of oscillatory energy are combustion and cavitation. Included in the example problems is a sampling of signal analysis tools employed in diagnostics. The rocket engine hardware includes combustion devices, valves, turbopumps, and ducts. Simple models of an oscillating fluid system or structure can be constructed to estimate pertinent dynamic parameters governing the unsteady behavior of engine systems or components. In the example problems it is shown that simple physical modeling when combined with signal analysis can be successfully employed to diagnose complex rocket engine oscillatory phenomena.

  5. Advanced Laser-Based Techniques for Gas-Phase Diagnostics in Combustion and Aerospace Engineering.

    PubMed

    Ehn, Andreas; Zhu, Jiajian; Li, Xuesong; Kiefer, Johannes

    2017-03-01

    Gaining information of species, temperature, and velocity distributions in turbulent combustion and high-speed reactive flows is challenging, particularly for conducting measurements without influencing the experimental object itself. The use of optical and spectroscopic techniques, and in particular laser-based diagnostics, has shown outstanding abilities for performing non-intrusive in situ diagnostics. The development of instrumentation, such as robust lasers with high pulse energy, ultra-short pulse duration, and high repetition rate along with digitized cameras exhibiting high sensitivity, large dynamic range, and frame rates on the order of MHz, has opened up for temporally and spatially resolved volumetric measurements of extreme dynamics and complexities. The aim of this article is to present selected important laser-based techniques for gas-phase diagnostics focusing on their applications in combustion and aerospace engineering. Applicable laser-based techniques for investigations of turbulent flows and combustion such as planar laser-induced fluorescence, Raman and Rayleigh scattering, coherent anti-Stokes Raman scattering, laser-induced grating scattering, particle image velocimetry, laser Doppler anemometry, and tomographic imaging are reviewed and described with some background physics. In addition, demands on instrumentation are further discussed to give insight in the possibilities that are offered by laser flow diagnostics.

  6. Detecting and diagnosing hotspots for the enhanced management of hospital emergency departments in Queensland, Australia

    PubMed Central

    2013-01-01

    Background Predictive tools are already being implemented to assist in Emergency Department bed management by forecasting the expected total volume of patients. Yet these tools are unable to detect and diagnose when estimates fall short. Early detection of hotspots, that is subpopulations of patients presenting in unusually high numbers, would help authorities to manage limited health resources and communicate effectively about emerging risks. We evaluate an anomaly detection tool that signals when, and in what way Emergency Departments in 18 hospitals across the state of Queensland, Australia, are significantly exceeding their forecasted patient volumes. Methods The tool in question is an adaptation of the Surveillance Tree methodology initially proposed in Sparks and Okugami (IntStatl 1:2–24, 2010). for the monitoring of vehicle crashes. The methodology was trained on presentations to 18 Emergency Departments across Queensland over the period 2006 to 2008. Artificial increases were added to simulated, in-control counts for these data to evaluate the tool’s sensitivity, timeliness and diagnostic capability. The results were compared with those from a univariate control chart. The tool was then applied to data from 2009, the year of the H1N1 (or ‘Swine Flu’) pandemic. Results The Surveillance Tree method was found to be at least as effective as a univariate, exponentially weighted moving average (EWMA) control chart when increases occurred in a subgroup of the monitored population. The method has advantages over the univariate control chart in that it allows for the monitoring of multiple disease groups while still allowing control of the overall false alarm rate. It is also able to detect changes in the makeup of the Emergency Department presentations, even when the total count remains unchanged. Furthermore, the Surveillance Tree method provides diagnostic information useful for service improvements or disease management. Conclusions Multivariate surveillance provides a useful tool in the management of hospital Emergency Departments by not only efficiently detecting unusually high numbers of presentations, but by providing information about which groups of patients are causing the increase. PMID:24313914

  7. Development of the Technology of Vortex Diagnostics to Improve the Safety of Operation of Nuclear Reactors

    NASA Astrophysics Data System (ADS)

    Mitrofanova, O. V.; Ivlev, O. A.; Pozdeeva, I. G.; Urtenov, D. S.

    2017-11-01

    The results of studies are aimed at developing theoretical foundations and instrumentation system to ensure a technology of vortex diagnostics of the state of flows of fluids for nuclear power installations with power water reactors and fast neutrons reactors with liquid-metal coolants. The technology of vortex diagnostics is based on the study of acoustic, magneto-hydrodynamic and resonant effects related to the formation of stable vortex structures. For creation a system of monitoring and diagnostics of the crisis phenomena due to hydrodynamics of the flow, it is proposed to use acoustic method to record the radiation of elastic waves in the fluids caused by the dynamic local rearrangement of its structure.

  8. Estimated United States Residential Energy Use in 2005

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Smith, C A; Johnson, D M; Simon, A J

    2011-12-12

    A flow chart depicting energy flow in the residential sector of the United States economy in 2005 has been constructed from publicly available data and estimates of national energy use patterns. Approximately 11,000 trillion British Thermal Units (trBTUs) of electricity and fuels were used throughout the United States residential sector in lighting, electronics, air conditioning, space heating, water heating, washing appliances, cooking appliances, refrigerators, and other appliances. The residential sector is powered mainly by electricity and natural gas. Other fuels used include petroleum products (fuel oil, liquefied petroleum gas and kerosene), biomass (wood), and on-premises solar, wind, and geothermal energy.more » The flow patterns represent a comprehensive systems view of energy used within the residential sector.« less

  9. Development of a computer code for calculating the steady super/hypersonic inviscid flow around real configurations. Volume 1: Computational technique

    NASA Technical Reports Server (NTRS)

    Marconi, F.; Salas, M.; Yaeger, L.

    1976-01-01

    A numerical procedure has been developed to compute the inviscid super/hypersonic flow field about complex vehicle geometries accurately and efficiently. A second order accurate finite difference scheme is used to integrate the three dimensional Euler equations in regions of continuous flow, while all shock waves are computed as discontinuities via the Rankine Hugoniot jump conditions. Conformal mappings are used to develop a computational grid. The effects of blunt nose entropy layers are computed in detail. Real gas effects for equilibrium air are included using curve fits of Mollier charts. Typical calculated results for shuttle orbiter, hypersonic transport, and supersonic aircraft configurations are included to demonstrate the usefulness of this tool.

  10. Development of a computer code for calculating the steady super/hypersonic inviscid flow around real configurations. Volume 2: Code description

    NASA Technical Reports Server (NTRS)

    Marconi, F.; Yaeger, L.

    1976-01-01

    A numerical procedure was developed to compute the inviscid super/hypersonic flow field about complex vehicle geometries accurately and efficiently. A second-order accurate finite difference scheme is used to integrate the three-dimensional Euler equations in regions of continuous flow, while all shock waves are computed as discontinuities via the Rankine-Hugoniot jump conditions. Conformal mappings are used to develop a computational grid. The effects of blunt nose entropy layers are computed in detail. Real gas effects for equilibrium air are included using curve fits of Mollier charts. Typical calculated results for shuttle orbiter, hypersonic transport, and supersonic aircraft configurations are included to demonstrate the usefulness of this tool.

  11. A Computer Code for Swirling Turbulent Axisymmetric Recirculating Flows in Practical Isothermal Combustor Geometries

    NASA Technical Reports Server (NTRS)

    Lilley, D. G.; Rhode, D. L.

    1982-01-01

    A primitive pressure-velocity variable finite difference computer code was developed to predict swirling recirculating inert turbulent flows in axisymmetric combustors in general, and for application to a specific idealized combustion chamber with sudden or gradual expansion. The technique involves a staggered grid system for axial and radial velocities, a line relaxation procedure for efficient solution of the equations, a two-equation k-epsilon turbulence model, a stairstep boundary representation of the expansion flow, and realistic accommodation of swirl effects. A user's manual, dealing with the computational problem, showing how the mathematical basis and computational scheme may be translated into a computer program is presented. A flow chart, FORTRAN IV listing, notes about various subroutines and a user's guide are supplied as an aid to prospective users of the code.

  12. Diagnostic criteria for mass lesions differentiating in electrical impedance mammography

    NASA Astrophysics Data System (ADS)

    A, Karpov; M, Korotkova

    2013-04-01

    The purpose of this research was to determine the diagnostic criteria for differentiating volumetric lesions in the mammary gland in electrical impedance mammography. The research was carried out utilizing the electrical impedance computer mammograph llMEIK v.5.6gg®, which enables to acquire images of 3-D conductivity distribution layers within mamma's tissues up to 5 cm depth. The weighted reciprocal projection method was employed to reconstruct the 3-D electric conductivity distribution of the examined organ. The results of 3,710 electrical impedance examinations were analyzed. The analysis of a volumetric lesion included assessment of its shape, contour, internal electrical structure and changes of the surrounding tissues. Moreover, mammary gland status was evaluated with the help of comparative and age-related electrical conductivity curves. The diagnostic chart is provided. Each criterion is measured in points. Using the numerical score for evaluation of mass and non-volumetric lesions within the mammary gland in electrical impedance mammography allowed comparing this information to BI-RADS categories developed by American College of Radiology experts. The article is illustrated with electrical impedance mammograms and tables.

  13. Rarefied flow diagnostics using pulsed high-current electron beams

    NASA Technical Reports Server (NTRS)

    Wojcik, Radoslaw M.; Schilling, John H.; Erwin, Daniel A.

    1990-01-01

    The use of high-current short-pulse electron beams in low-density gas flow diagnostics is introduced. Efficient beam propagation is demonstrated for pressure up to 300 microns. The beams, generated by low-pressure pseudospark discharges in helium, provide extremely high fluorescence levels, allowing time-resolved visualization in high-background environments. The fluorescence signal frequency is species-dependent, allowing instantaneous visualization of mixing flowfields.

  14. Determination of wind from NIMBUS 6 satellite sounding data

    NASA Technical Reports Server (NTRS)

    Carle, W. E.; Scoggins, J. R.

    1981-01-01

    Objective methods of computing upper level and surface wind fields from NIMBUS 6 satellite sounding data are developed. These methods are evaluated by comparing satellite derived and rawinsonde wind fields on gridded constant pressure charts in four geographical regions. Satellite-derived and hourly observed surface wind fields are compared. Results indicate that the best satellite-derived wind on constant pressure charts is a geostrophic wind derived from highly smoothed fields of geopotential height. Satellite-derived winds computed in this manner and rawinsonde winds show similar circulation patterns except in areas of small height gradients. Magnitudes of the standard deviation of the differences between satellite derived and rawinsonde wind speeds range from approximately 3 to 12 m/sec on constant pressure charts and peak at the jet stream level. Fields of satellite-derived surface wind computed with the logarithmic wind law agree well with fields of observed surface wind in most regions. Magnitudes of the standard deviation of the differences in surface wind speed range from approximately 2 to 4 m/sec, and satellite derived surface winds are able to depict flow across a cold front and around a low pressure center.

  15. Angina Relief by Ranolazine Identifies False-Negative SPECT Myocardial Perfusion Scans in Patients with Coronary Disease Demonstrated by Coronary Angiography.

    PubMed

    Murray, Gary L

    2014-09-01

    Normal myocardial perfusion imaging (MPI) reduces intermediate- or high-risk pretest probability patients to low- or intermediate-risk posttest probability, respectively, for coronary disease (CD). Since ranolazine (RAN) relieves only angina, anginal patients with normal MPI whose angina is relieved by RAN present a significant dilemma. The purpose of this retrospective chart review was to confirm the impression that coronary angiography (CA) is indicated in patients whose class 3 to 4 angina is relieved by RAN, but have normal myocardial single-photon emission computed tomography (SPECT) MPIs. Charts of patients with stable class 3 to 4 angina (typical and atypical) and normal MPIs (left ventricular ejection fraction [LVEF] ≥50% and segmental score = 0) were reviewed. CA was done on all the patients with complete angina relief taking RAN, as well as nonresponders whose anginal etiology could not be explained. Stenoses were considered flow-restrictive when more than 70% diameter stenosis is observed by quantitative CA, or, when 50 to 70%, fractional flow reserve (FFR) measured ≤0.80. RAN relieved angina in 36 of 54 (67%) patients. Of the known cases, 25 of these 36 (69%) had 43 stenoses ≥50% (mean = 66%): 15 (60%) had 1 vessel disease; 9 (36%) had multivessel disease; 18 (72%) had left anterior descending (LAD) disease; 1 (4%) had left main disease. Twenty one of 43 (49%) stenosis were > 70%; 22 (51%) stenoses were 50 to 70% and required FFR measurement. Twenty nine of 43 stenoses (67%) were considered flow-restrictive in 18 of these 25 (72%) patients. Eight RAN nonresponders with no explanation for angina had no CD at CA. RAN angina relief is invaluable in identifying falsely negative SPECT MPI, and 50% of these patients have flow-restrictive stenoses.

  16. Making large amounts of meteorological plots easily accessible to users

    NASA Astrophysics Data System (ADS)

    Lamy-Thepaut, Sylvie; Siemen, Stephan; Sahin, Cihan; Raoult, Baudouin

    2015-04-01

    The European Centre for Medium-Range Weather Forecasts (ECMWF) is an international organisation providing its member organisations with forecasts in the medium time range of 3 to 15 days, and some longer-range forecasts for up to a year ahead, with varying degrees of detail. As part of its mission, ECMWF generates an increasing number of forecast data products for its users. To support the work of forecasters and researchers and to let them make best use of ECMWF forecasts, the Centre also provides tools and interfaces to visualise their products. This allows users to make use of and explore forecasts without having to transfer large amounts of raw data. This is especially true for products based on ECMWF's 50 member ensemble forecast, where some specific processing and visualisation are applied to extract information. Every day, thousands of raw data are being pushed to the ECMWF's interactive web charts application called ecCharts, and thousands of products are processed and pushed to ECMWF's institutional web site ecCharts provides a highly interactive application to display and manipulate recent numerical forecasts to forecasters in national weather services and ECMWF's commercial customers. With ecCharts forecasters are able to explore ECMWF's medium-range forecasts in far greater detail than has previously been possible on the web, and this as soon as the forecast becomes available. All ecCharts's products are also available through a machine-to-machine web map service based on the OGC Web Map Service (WMS) standard. ECMWF institutional web site provides access to a large number of graphical products. It was entirely redesigned last year. It now shares the same infrastructure as ECMWF's ecCharts, and can benefit of some ecCharts functionalities, for example the dashboard. The dashboard initially developed for ecCharts allows users to organise their own collection of products depending on their work flow, and is being further developed. In its first implementation, It presents the user's products in a single interface with fast access to the original product, and possibilities of synchronous animations between them. But its functionalities are being extended to give users the freedom to collect not only ecCharts's 2D maps and graphs, but also other ECMWF Web products such as monthly and seasonal products, scores, and observation monitoring. The dashboard will play a key role to help the user to interpret the large amount of information that ECMWF is providing. This talk will present examples of how the new user interface can organise complex meteorological maps and graphs and show the new possibilities users have gained by using the web as a medium.

  17. Virtual Resting Pd/Pa From Coronary Angiography and Blood Flow Modelling: Diagnostic Performance Against Fractional Flow Reserve.

    PubMed

    Papafaklis, Michail I; Muramatsu, Takashi; Ishibashi, Yuki; Bourantas, Christos V; Fotiadis, Dimitrios I; Brilakis, Emmanouil S; Garcia-Garcia, Héctor M; Escaned, Javier; Serruys, Patrick W; Michalis, Lampros K

    2018-03-01

    Fractional flow reserve (FFR) has been established as a useful diagnostic tool. The distal coronary pressure to aortic pressure (Pd/Pa) ratio at rest is a simpler physiologic index but also requires the use of the pressure wire, whereas recently proposed virtual functional indices derived from coronary imaging require complex blood flow modelling and/or are time-consuming. Our aim was to test the diagnostic performance of virtual resting Pd/Pa using routine angiographic images and a simple flow model. Three-dimensional quantitative coronary angiography (3D-QCA) was performed in 139 vessels (120 patients) with intermediate lesions assessed by FFR. The resting Pd/Pa for each lesion was assessed by computational fluid dynamics. The discriminatory power of virtual resting Pd/Pa against FFR (reference: ≤0.80) was high (area under the receiver operator characteristic curve [AUC]: 90.5% [95% CI: 85.4-95.6%]). Diagnostic accuracy, sensitivity and specificity for the optimal virtual resting Pd/Pa cut-off (≤0.94) were 84.9%, 90.4% and 81.6%, respectively. Virtual resting Pd/Pa demonstrated superior performance (p<0.001) versus 3D-QCA %area stenosis (AUC: 77.5% [95% CI: 69.8-85.3%]). There was a good correlation between virtual resting Pd/Pa and FFR (r=0.69, p<0.001). Virtual resting Pd/Pa using routine angiographic data and a simple flow model provides fast functional assessment of coronary lesions without requiring the pressure-wire and hyperaemia induction. The high diagnostic performance of virtual resting Pd/Pa for predicting FFR shows promise for using this simple/fast virtual index in clinical practice. Copyright © 2017 Australian and New Zealand Society of Cardiac and Thoracic Surgeons (ANZSCTS) and the Cardiac Society of Australia and New Zealand (CSANZ). Published by Elsevier B.V. All rights reserved.

  18. Thyroid lymphoma: diagnostic pitfalls on pre-operative ago-biopsy.

    PubMed

    Antonino, Antonio; Rosato, Andrea; Barbato, Filomena; De Dominicis, Gianfranco; De Palma, Maurizio

    2013-01-01

    Thyroid cancer has the highest prevalence of all endocrine malignancies. Malignancy can be of thyroid or non-thyroid origin. Sarcomas and primary thyroid lymphomas (PTL) are rare and surgery is treatment of choice in the former but not in latter. To describe thyroid lymphomas histological types of thyroid cancer found in a reference center. Medical chart review from admitted patients diagnosed with thyroid cancer in the period from january 2007 to june 2012. Demographic, diagnostic, therapeutic and histopathological information were collected. 1604 records of patients admitted with thyroid disease were reviewed. Among 307 thyroid cancer, the cases diagnosed with rare tumors were: 10 cases of anaplastic carcinoma (3.5%), followed by 4 cases of medullary carcinoma (1.3%), 1 cases of teratoma (0.03%), 2 cases of lymphoma (0.06%). The most frequent clinical presentation was a palpable thyroid nodule. All patients with lymphoma died. Thyroid lymphomas are uncommon and tend to worse outcomes.

  19. The association between self-reported anxiety symptoms and suicidality.

    PubMed

    Diefenbach, Gretchen J; Woolley, Stephen B; Goethe, John W

    2009-02-01

    This cross-sectional study assessed the association between self-reported anxiety symptoms and self-reported suicidality among a mixed diagnostic sample of psychiatric outpatients. Data were obtained from chart review of 2,778 outpatients who completed a routine diagnostic clinical interview and a standardized self-report of psychiatric symptoms on admission. Bivariate analyses indicated that those with >or= moderate anxiety symptoms were over three times as likely to report >or= moderate difficulty with suicidality. Self-reported anxiety symptoms were associated with a 2-fold increased likelihood of reporting suicidality after controlling for confounding (demographics, depressive symptoms, and diagnoses). These data are consistent with a growing literature demonstrating an association between anxiety symptoms and suicidality, and suggest that this association is not accounted for by coexisting mood symptoms or diagnoses. A single item, self-report may be a useful screening tool for symptoms that are pertinent to assessment of suicide risk.

  20. Interventions to Enhance Breast Cancer Screening, Diagnosis, and Treatment among Racial and Ethnic Minority Women

    PubMed Central

    Masi, Christopher M.; Blackman, Dionne J.; Peek, Monica E.

    2009-01-01

    The authors conduct a systematic review of the literature to identify interventions designed to enhance breast cancer screening, diagnosis, and treatment among minority women. Most trials in this area have focused on breast cancer screening, while relatively few have addressed diagnostic testing or breast cancer treatment. Among patient-targeted screening interventions, those that are culturally tailored or addressed financial or logistical barriers are generally more effective than reminder-based interventions, especially among women with fewer financial resources and those without previous mammography. Chart-based reminders increase physician adherence to mammography guidelines but are less effective at increasing clinical breast examination. Several trials demonstrate that case management is an effective strategy for expediting diagnostic testing after screening abnormalities have been found. Additional support for these and other proven health care organization-based interventions appears justified and may be necessary to eliminate racial and ethnic breast cancer disparities. PMID:17881627

  1. Integrated Analytical Evaluation and Optimization of Model Parameters against Preprocessed Measurement Data

    DTIC Science & Technology

    1989-06-23

    Iterations .......................... 86 3.2 Comparison between MACH and POLAR ......................... 90 3.3 Flow Chart for VSTS Algorithm...The most recent changes are: a) development of the VSTS (velocity space topology search) algorithm for calculating particle densities b) extension...with simple analytic models. The largest modification of the MACH code was the implementation of the VSTS procedure, which constituted a complete

  2. Numerical Implementation of Indicators and Statistical Control Tools in Monitoring and Evaluating CACEI-ISO Indicators of Study Program in Industrial Process by Systematization

    ERIC Educational Resources Information Center

    Ayala, Gabriela Cota; Real, Francia Angélica Karlos; Ivan, Ramirez Alvarado Edqar

    2016-01-01

    The research was conducted to determine if the study program of the career of industrial processes Technological University of Chihuahua, 1 year after that it was certified by CACEI, continues achieving the established indicators and ISO 9001: 2008, implementing quality tools, monitoring of essential indicators are determined, flow charts are…

  3. Real-Time Signal Processing Systems

    DTIC Science & Technology

    1992-10-29

    Programmer’s Model 50 15. Synchronization 67 16. Parameter Passage to Routines VIA Stacks 68 17. Typical VPH Activity Flow Chart 70 18. CPH...computing facilities to take advantage of cost effective solutions. A proliferation of different microprocessors and development systems spread among the... activities are completed, the roles of the VPH memory banks are reversed. This function-swapping is the primary reason, for the efficiency and high

  4. Las Matematicas: Lenguaje Universal. Nivel 1: Numeros y Numeracion (Mathematics: A Universal Language. Level 1: Numbers and Numeration).

    ERIC Educational Resources Information Center

    Dissemination and Assessment Center for Bilingual Education, Austin, TX.

    This is one of a series of student booklets designed for use in a bilingual mathematics program in grades 6-8. The general format is to present each page in both Spanish and English. The mathematical topics in this booklet include graphing on a number line, place value, using exponents, flow charts, and Roman numerals. (MK)

  5. Design of Training Systems, Phase II Report, Volume III; Model Program Descriptions and Operating Procedures. TAEG Report No. 12-2.

    ERIC Educational Resources Information Center

    Naval Training Equipment Center, Orlando, FL. Training Analysis and Evaluation Group.

    The Design of Training Systems (DOTS) project was initiated by the Department of Defense (DOD) to develop tools for the effective management of military training organizations. Volume 3 contains the model and data base program descriptions and operating procedures designed for phase 2 of the project. Flow charts and program listings for the…

  6. Host computer software specifications for a zero-g payload manhandling simulator

    NASA Technical Reports Server (NTRS)

    Wilson, S. W.

    1986-01-01

    The HP PASCAL source code was developed for the Mission Planning and Analysis Division (MPAD) of NASA/JSC, and takes the place of detailed flow charts defining the host computer software specifications for MANHANDLE, a digital/graphical simulator that can be used to analyze the dynamics of onorbit (zero-g) payload manhandling operations. Input and output data for representative test cases are contained.

  7. Subsurface-water flow and solute transport: federal glossary of selected terms

    USGS Publications Warehouse

    Isensee, Alan R.; Johnson, Lynn; Thornhill, Jerry; Nicholson, Thomas J.; Meyer, Gerald; Vecchioli, John; Laney, Robert

    1989-01-01

    The definitions and conversion charts are from two principal sources provided herein. The first is the 11Glossary11 compiled by A. I. Johnson in the 1981 report by the American Society of Testing and Materials titled Permeability and Groundwater Contaminant Transport. The second is Manu a 1 40, 11Ground-water Management, 11 produced by the American Society of Civil Engineers in 1985.

  8. RF multicoupler design techniques to minimize problems of corona, multipaction, and stability

    NASA Technical Reports Server (NTRS)

    Hurley, H. S.; Kozakoff, D. J.

    1971-01-01

    A mathematical expression was derived describing multipacting and corona effects in a coaxial cavity. Both mechanical and electrical design techniques were investigated to minimize the susceptibility of coaxial cavity to corona and multipacting-type breakdown. To assist in the design of a multicoupler free from corona and multipactor breakdown, a flow chart obtained from the derived mathematical expression is included.

  9. A real-time digital computer program for the simulation of a single rotor helicopter

    NASA Technical Reports Server (NTRS)

    Houck, J. A.; Gibson, L. H.; Steinmetz, G. G.

    1974-01-01

    A computer program was developed for the study of a single-rotor helicopter on the Langley Research Center real-time digital simulation system. Descriptions of helicopter equations and data, program subroutines (including flow charts and listings), real-time simulation system routines, and program operation are included. Program usage is illustrated by standard check cases and a representative flight case.

  10. Evaluation of a Technology for Teaching Complex Social Skills to Young Adults with Visual and Cognitive Impairments.

    ERIC Educational Resources Information Center

    Gumpel, Thomas P.; Nativ-Ari-Am, Hagit

    2001-01-01

    Two multiple baseline designs were used to evaluate a two-stage model for training four young adults with visual and cognitive impairments to grocery shop. A task-analytical flow chart of the behavioral skills involved in grocery shopping was used to increase completed skill steps and the number of correct items purchased. (Contains references.)…

  11. Documentation of a ground hydrology parameterization for use in the GISS atmospheric general circulation model

    NASA Technical Reports Server (NTRS)

    Lin, J. D.; Aleano, J.; Bock, P.

    1978-01-01

    The moisture transport processes related to the earth's surface relevant to the ground circulation model GCM are presented. The GHM parametrizations considered are: (1) ground wetness and soil parameters; (2) precipitation; (3) evapotranspiration; (4) surface storage of snow and ice; and (5) runout. The computational aspects of the GHM using computer programs and flow charts are described.

  12. Nanoporous Glass Integrated in Volumetric Bar-Chart Chip for Point-of-Care Diagnostics of Non-Small Cell Lung Cancer.

    PubMed

    Li, Ying; Xuan, Jie; Song, Yujun; Qi, Wenjin; He, Bangshun; Wang, Ping; Qin, Lidong

    2016-01-26

    Point-of-care (POC) testing has the potential to enable rapid, low-cost, and large-scale screening. POC detection of a multiplexed biomarker panel can facilitate the early diagnosis of non-small cell lung cancer (NSCLC) and, thus, may allow for more timely surgical intervention for life-saving treatment. Herein, we report the nanoporous glass (NPG) integrated volumetric bar-chart chip (V-Chip) for POC detection of the three NSCLC biomarkers CEA, CYFRA 21-1, and SCCA, by the naked eye. The 3D nanostructures in the NPG membrane efficiently increase the number of binding sites for antibodies and decrease the diffusion distance between antibody and antigen, enabling the low detection limit and rapid analysis time of the NPG-V-Chip. We utilized the NPG-V-Chip to test the NSCLC biomarker panel and found that the limit of detection can reach 50 pg/mL (10-fold improvement over the original V-Chip), and the total assay time can be decreased from 4 to 0.5 h. We then detected CEA in 21 serum samples from patients with common cancers, and the on-chip results showed good correlation with the clinical results. We further assayed 10 lung cancer samples using the device and confirmed the results obtained using conventional ELISA methods. In summary, the NPG-V-Chip platform has the ability of multiplex, low detection limit, low cost, lack of need for accessory equipment, and rapid analysis time, which may render the V-Chip a useful platform for quantitative POC detection in resource-limited settings and personalized diagnostics.

  13. [Etiology and diagnostic methods in vocal cord paralysis].

    PubMed

    Jørgensen, Gita; Clausen, Eva Wiinstedt; Mantoni, Margit Y; Misciattelli, Lorenzo; Balle, Viggo

    2003-02-10

    The etiology of vocal cord paralysis (VCP) is varied. There is lack of consensus regarding the choice of investigations to be used in the evaluation of VCP. The aim of this study was to establish the etiology, assess the diagnostic methods used in the evaluation, and outline an algorithm for future evaluation of unilateral vocal cord paralysis (UVCP). Charts of all patients (n = 94) with the diagnostic code of VCP were reviewed, and reexaminations were performed of patients in whom no etiology was found after the initial symptoms. The etiology of UVCP was neoplasm in 34%, surgical trauma in 12%, and miscellaneous causes in 54%. The etiology of bilateral vocal cord paralysis (BVCP) was neoplasm in 24%, surgical trauma in 24%, and miscellaneous causes in 52%. The reexaminations did not reveal any cancer diseases in the patients concerned. The most effective diagnostic method was CT-scanning while the least effective was thyroid scanning. Because cancer is a common cause of VCP a thorough evaluation is necessary. For UVCP we recommend history and physical examination, X-ray of the chest, ultrasonography of the neck, and CT-scanning of the superior mediastinum. If these prove negative, panendoscopy should be performed. Workup of patients with idiopathic VCP should include examination, X-ray of the chest at 6-month intervals, and annual CT-scanning for two years.

  14. Diagnostic and Therapeutic Knowledge and Practices in the Management of Congenital Syphilis by Pediatricians in Public Maternity Hospitals in Brazil.

    PubMed

    Dos Santos, Raquel Rodrigues; Niquini, Roberta Pereira; Bastos, Francisco Inácio; Domingues, Rosa Maria Soares Madeira

    2017-01-01

    The study aimed to assess conformity with Brazil's standard protocol for diagnostic and therapeutic practices in the management of congenital syphilis by pediatricians in public maternity hospitals. A cross-sectional study was conducted in 2015 with 41 pediatricians working in all the public maternity hospitals in Teresina, the capital of Piauí State, Northeast Brazil, through self-completed questionnaires. The study assessed the conformity of knowledge and practices according to the Brazilian Ministry of Health protocols. The study has made evident low access to training courses (54%) and insufficient knowledge of the case definition of congenital syphilis (42%) and rapid tests for syphilis (39%). Flaws were observed in the diagnostic workup and treatment of newborns. Requesting VDRL (88%) and correct treatment of neurosyphilis (88%) were the practices that showed the highest conformity with standard protocols. Low conformity with protocols leads to missed opportunities for identifying and adequately treating congenital syphilis. Based on the barriers identified in the study, better access to diagnostic and treatment protocols, improved recording on prenatal cards and hospital patient charts, availability of tests and medicines, and educational work with pregnant women should be urgently implemented, aiming to reverse the currently inadequate management of congenital syphilis and to curb its spread.

  15. Prospects for Nonlinear Laser Diagnostics in the Jet Noise Laboratory

    NASA Technical Reports Server (NTRS)

    Herring, Gregory C.; Hart, Roger C.; Fletcher, mark T.; Balla, R. Jeffrey; Henderson, Brenda S.

    2007-01-01

    Two experiments were conducted to test whether optical methods, which rely on laser beam coherence, would be viable for off-body flow measurement in high-density, compressible-flow wind tunnels. These tests measured the effects of large, unsteady density gradients on laser diagnostics like laser-induced thermal acoustics (LITA). The first test was performed in the Low Speed Aeroacoustics Wind Tunnel (LSAWT) of NASA Langley Research Center's Jet Noise Laboratory (JNL). This flow facility consists of a dual-stream jet engine simulator (with electric heat and propane burners) exhausting into a simulated flight stream, reaching Mach numbers up to 0.32. A laser beam transited the LSAWT flow field and was imaged with a high-speed gated camera to measure beam steering and transverse mode distortion. A second, independent test was performed on a smaller laboratory jet (Mach number < 1.2 and mass flow rate < 0.1 kg/sec). In this test, time-averaged LITA velocimetry and thermometry were performed at the jet exit plane, where the effect of unsteady density gradients is observed on the LITA signal. Both experiments show that LITA (and other diagnostics relying on beam overlap or coherence) faces significant hurdles in the high-density, compressible, and turbulent flow environments similar to those of the JNL.

  16. Empirical flow parameters : a tool for hydraulic model validity

    USGS Publications Warehouse

    Asquith, William H.; Burley, Thomas E.; Cleveland, Theodore G.

    2013-01-01

    The objectives of this project were (1) To determine and present from existing data in Texas, relations between observed stream flow, topographic slope, mean section velocity, and other hydraulic factors, to produce charts such as Figure 1 and to produce empirical distributions of the various flow parameters to provide a methodology to "check if model results are way off!"; (2) To produce a statistical regional tool to estimate mean velocity or other selected parameters for storm flows or other conditional discharges at ungauged locations (most bridge crossings) in Texas to provide a secondary way to compare such values to a conventional hydraulic modeling approach. (3.) To present ancillary values such as Froude number, stream power, Rosgen channel classification, sinuosity, and other selected characteristics (readily determinable from existing data) to provide additional information to engineers concerned with the hydraulic-soil-foundation component of transportation infrastructure.

  17. Analytical Derivation and Experimental Evaluation of Short-Bearing Approximation for Full Journal Bearing

    NASA Technical Reports Server (NTRS)

    Dubois, George B; Ocvirk, Fred W

    1953-01-01

    An approximate analytical solution including the effect of end leakage from the oil film of short plain bearings is presented because of the importance of endwise flow in sleeve bearings of the short lengths commonly used. The analytical approximation is supported by experimental data, resulting in charts which facilitate analysis of short plain bearings. The analytical approximation includes the endwise flow and that part of the circumferential flow which is related to surface velocity and film thickness but neglects the effect of film pressure on the circumferential flow. In practical use, this approximation applies best to bearings having a length-diameter ratio up to 1, and the effects of elastic deflection, inlet oil pressure, and changes of clearance with temperature minimize the relative importance of the neglected term. The analytical approximation was found to be an extension of a little-known pressure-distribution function originally proposed by Michell and Cardullo.

  18. With simple gasoline stripping devices, a problem of gas transportation by pipeline is resolved (in Spanish)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Couto, J.A.

    1975-06-01

    Liquid hydrocarbons contained in Argentina's Pico Truncade natural gas caused a number of serious pipeline transmission and gas processing problems. Gas del Estado has installed a series of efficient liquid removal devices at the producing fields. A flow chart of the gasoline stripping process is illustrated, as are 2 types of heat exchangers. This process of gasoline stripping (gas condensate recovery) integrates various operations which normally are performed independently: separation of the poor condensate in the gas, stabilization of the same, and incorporation of the light components (products of the stabilization) in the main gas flow.

  19. A comparison of multiprocessor scheduling methods for iterative data flow architectures

    NASA Technical Reports Server (NTRS)

    Storch, Matthew

    1993-01-01

    A comparative study is made between the Algorithm to Architecture Mapping Model (ATAMM) and three other related multiprocessing models from the published literature. The primary focus of all four models is the non-preemptive scheduling of large-grain iterative data flow graphs as required in real-time systems, control applications, signal processing, and pipelined computations. Important characteristics of the models such as injection control, dynamic assignment, multiple node instantiations, static optimum unfolding, range-chart guided scheduling, and mathematical optimization are identified. The models from the literature are compared with the ATAMM for performance, scheduling methods, memory requirements, and complexity of scheduling and design procedures.

  20. Clinical and psychological features of children and adolescents diagnosed with avoidant/restrictive food intake disorder in a pediatric tertiary care eating disorder program: a descriptive study.

    PubMed

    Cooney, Megan; Lieberman, Melissa; Guimond, Tim; Katzman, Debra K

    2018-01-01

    Avoidant/Restrictive Food Intake Disorder (ARFID) is an eating disorder first described in the Diagnostic and Statistical Manual of Mental Disorders, 5th edition (DSM-5) [American Psychiatric Association, Diagnostic and statistical manual of mental disorders, 2013]. Patients with ARFID do not fear gaining weight or have body image distortions. ARFID involves a persistent disturbance in feeding and eating that results in an inability to meet nutritional and/or energy needs with one of the following: weight loss or failure to achieve appropriate weight gain, nutritional deficiency, dependence on enteral feeding or nutritional supplements and significant interference with psychosocial functioning. To date, studies on patients with ARFID have retrospectively applied the DSM-5 diagnostic criteria for ARFID to reclassify patients diagnosed with DSM-IV eating disorders. A descriptive retrospective chart review was completed on patients less than 18-years diagnosed with ARFID after a comprehensive eating disorder assessment between May 2013 and March 2016. The data collected included demographics, anthropometrics, historical information, clinical features, co-morbid diagnoses, need for inpatient hospitalization and psychometric measures. Three hundred and sixty-nine patients were assessed for an eating disorder between May 2013 and March 2016. Of these, 31 (8.4%) received a DSM-5 diagnosis of ARFID. A full chart review was performed on 28 (90.3%) patients. Weight loss or failure to achieve appropriate weight gain was the reason for diagnosis in 96.4% (27/28). All of our patients had 2 or more physical symptoms at the time of diagnosis and 16 (57.1%) had a co-morbid psychiatric disorder. Twenty (71.4%) reported a specific trigger for their eating disturbance. Admission for inpatient hospitalization occurred in 57.1% (16/28) of patients. Thirteen (46.4%) patients had been previously assessed by another specialist for their eating disturbance. None of the patients had elevated scores on commonly used psychometric tests used to assess eating disorders. This is the first study to retrospectively determine the incidence of ARFID in children and adolescents using the DSM-5 diagnostic criteria at assessment. The clinical presentation of patients with ARFID is complex with multiple physical symptoms and comorbid psychiatric disorders. Commonly used pediatric eating disorder psychometric measures are not specific for making a diagnosis of ARFID, and may not be sensitive as assessment tools.

  1. X-ray diagnostics of hohlraum plasma flow

    NASA Astrophysics Data System (ADS)

    Back, C. A.; Glenzer, S. H.; Landen, O. L.; MacGowan, B. J.; Shepard, T. D.

    1997-01-01

    In this study we use spectroscopy and x-ray imaging to investigate the macroscopic plasma flow in mm-sized laser-produced hohlraum plasmas. By using multiple diagnostics to triangulate the emission on a single experiment, we can pinpoint the position of dopants placed inside the hohlraum. X-ray emission from the foil has been used in the past to measure electron temperature. Here we analyze the spatial movement of dopant plasmas for comparison to hydrodynamic calculations.

  2. Modifications to the streamtube curvature program. Volume 1: Program modifications and user's manual. [user manuals (computer programs) for transonic flow of nacelles and intake systems of turbofan engines

    NASA Technical Reports Server (NTRS)

    Ferguson, D. R.; Keith, J. S.

    1975-01-01

    The improvements which have been incorporated in the Streamtube Curvature Program to enhance both its computational and diagnostic capabilities are described. Detailed descriptions are given of the revisions incorporated to more reliably handle the jet stream-external flow interaction at trailing edges. Also presented are the augmented boundary layer procedures and a variety of other program changes relating to program diagnostics and extended solution capabilities. An updated User's Manual, that includes information on the computer program operation, usage, and logical structure, is presented. User documentation includes an outline of the general logical flow of the program and detailed instructions for program usage and operation. From the standpoint of the programmer, the overlay structure is described. The input data, output formats, and diagnostic printouts are covered in detail and illustrated with three typical test cases.

  3. [Foreign body aspiration in children].

    PubMed

    Cohen, Shlomo; Goldberg, Shmuel; Springer, Chaim; Avital, Avraham; Picard, Elie

    2015-03-01

    Foreign body (FB) aspiration occurs mainly in children under 3 years of age and is one of the most frequent causes of accidental death under 12 months of age. The increased risk of FB aspiration in children is due to the different structure of the pharynx and the upper airways compared to adults. In addition, children have an immature swallowing mechanism and they most commonly aspirate food stuffs. FB aspiration is usually a sudden and dramatic event when the child feels that he is suffocating or choking. After the acute event, the clinical presentation widely ranges from severe respiratory distress to the most minimal symptoms. Bronchoscopy is the best diagnostic and therapeutic modality for FB inhalation. Prevention and rapid diagnosis can be lifesaving. In 2010, the American Academy of Pediatrics published a position paper on prevention of FB aspiration. The association calls for more proactive preventative measures to protect children from FB aspiration and to prevent mortality and morbidity. These include: 1. Raising awareness of parents and caregivers to supervise children and create a safe environment for them. 2. Promoting legislation and enforcing regulations that will prevent dangerous products being sold for children. 3. Changing the design of products, especially food products and toys, that will reduce the risks of choking. In this overview we will show the principles of diagnosis of FB aspiration and a flow chart including when flexible or rigid bronchoscopy is required.

  4. The decentralisation of the sexually transmitted diseases service and its integration into primary health care.

    PubMed

    Latif, A S; Mbengeranwa, O L; Marowa, E; Paraiwa, E; Gutu, S

    1986-10-01

    As part of National Health Policy, the City Health Department in Harare, Zimbabwe decentralized sexually transmitted diseases (STD) services and integrated it into primary health care. A central referral STD clinic was created to concentrate expertise. Simplified treatment protocols were distributed to primary care clinics, and nurses in these clinics received an intensive 2-week training course at the central clinic. This was part of a larger plan to provide comprehensive health care in easily accessible settings. The Harare City Health Department has 14 primary care clinics and 9 polyclinics staffed mainly by nursing personnel. The training course taught curative treatment of STDs and prevention by patient education and locating sexual contacts. Participants were expected to be able to utilize physical and laboratory diagnostic techniques accurately to identify common STDs, and to order appropriate treatment. The program emphasized "bedside" teaching with continuous exposure to clinical problems and discussion of those problems. The textbook used included management guidelines in the form of flow charts adapted from World Health Organization guidelines. Over 16 weeks, 49 trainees attended the course. Trainees were mainly female, while patients are mainly male. Trainees performed well, gaining self confidence and ability to manage STDs. The main problems encountered were overwork of staff in clinics when 1 lest for the program, and reluctance of male patients to be examined by female trainees.

  5. Recognizing dangerous snakes in the United States and Canada: a novel 3-step identification method.

    PubMed

    Cardwell, Michael D

    2011-12-01

    The rapid and accurate recognition of dangerously venomous snakes following bites is crucial to making appropriate decisions regarding first aid, evacuation, and treatment. Past recommendations for identification of dangerous North American pit vipers have often required subjective determinations of head shape or relied on traits shared with some nondangerous species (elliptical pupils and undivided subcaudal scales). Heat-sensitive facial pits are diagnostic but require close examination of the dangerous head, and cephalic traits are useless when working with a decapitated carcass. Exclusive of cephalic traits, pit vipers north of Mexico can be recognized by the combination of keeled middorsal scales and undivided subcaudal scales. The order of colored rings is usually suggested to identify coral snakes in the United States, yet extension of the colored rings across the ventral scales must be added as an essential identifying factor to ensure elimination of all harmless look-alikes. A novel 3-step flow chart is presented that allows dangerous snakes in the United States and Canada to be recognized quickly and dependably without relying on cephalic traits. This process cannot be used in other countries, however, due to greater variability of these characteristics in snakes from other parts of the world. Finally, close examination of potentially venomous snakes is extraordinarily dangerous and steps to safeguard those making such observations are discussed. Copyright © 2011 Wilderness Medical Society. Published by Elsevier Inc. All rights reserved.

  6. Spectrum of mucocutaneous, ocular and facial features and delineation of novel presentations in 62 classical Ehlers-Danlos syndrome patients.

    PubMed

    Colombi, M; Dordoni, C; Venturini, M; Ciaccio, C; Morlino, S; Chiarelli, N; Zanca, A; Calzavara-Pinton, P; Zoppi, N; Castori, M; Ritelli, M

    2017-12-01

    Classical Ehlers-Danlos syndrome (cEDS) is characterized by marked cutaneous involvement, according to the Villefranche nosology and its 2017 revision. However, the diagnostic flow-chart that prompts molecular testing is still based on experts' opinion rather than systematic published data. Here we report on 62 molecularly characterized cEDS patients with focus on skin, mucosal, facial, and articular manifestations. The major and minor Villefranche criteria, additional 11 mucocutaneous signs and 15 facial dysmorphic traits were ascertained and feature rates compared by sex and age. In our cohort, we did not observe any mandatory clinical sign. Skin hyperextensibility plus atrophic scars was the most frequent combination, whereas generalized joint hypermobility according to the Beighton score decreased with age. Skin was more commonly hyperextensible on elbows, neck, and knees. The sites more frequently affected by abnormal atrophic scarring were knees, face (especially forehead), pretibial area, and elbows. Facial dysmorphism commonly affected midface/orbital areas with epicanthal folds and infraorbital creases more commonly observed in young patients. Our findings suggest that the combination of ≥1 eye dysmorphism and facial/forehead scars may support the diagnosis in children. Minor acquired traits, such as molluscoid pseudotumors, subcutaneous spheroids, and signs of premature skin aging are equally useful in adults. © 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  7. Initial Ada components evaluation

    NASA Technical Reports Server (NTRS)

    Moebes, Travis

    1989-01-01

    The SAIC has the responsibility for independent test and validation of the SSE. They have been using a mathematical functions library package implemented in Ada to test the SSE IV and V process. The library package consists of elementary mathematical functions and is both machine and accuracy independent. The SSE Ada components evaluation includes code complexity metrics based on Halstead's software science metrics and McCabe's measure of cyclomatic complexity. Halstead's metrics are based on the number of operators and operands on a logical unit of code and are compiled from the number of distinct operators, distinct operands, and total number of occurrences of operators and operands. These metrics give an indication of the physical size of a program in terms of operators and operands and are used diagnostically to point to potential problems. McCabe's Cyclomatic Complexity Metrics (CCM) are compiled from flow charts transformed to equivalent directed graphs. The CCM is a measure of the total number of linearly independent paths through the code's control structure. These metrics were computed for the Ada mathematical functions library using Software Automated Verification and Validation (SAVVAS), the SSE IV and V tool. A table with selected results was shown, indicating that most of these routines are of good quality. Thresholds for the Halstead measures indicate poor quality if the length metric exceeds 260 or difficulty is greater than 190. The McCabe CCM indicated a high quality of software products.

  8. Contemporary management and surveillance strategy after shunt or endoscopic third ventriculostomy procedures for hydrocephalus.

    PubMed

    Janjua, M Burhan; Hoffman, Caitlin E; Souweidane, Mark M

    2017-11-01

    The management of hydrocephalus can be challenging even in expert hands. Due to acute presentation, recurrence, accompanying complications, the need for urgent diagnosis; a robust management plan is an absolute necessity. We devised a novel time efficient surveillance strategy during emergency, and clinic follow up settings which has never been described in the literature. We searched all articles embracing management/surveillance protocol on pediatric hydrocephalus utilizing the terms "hydrocephalus follow up" or "surveillance protocol after hydrocephalus treatment". The authors present their own strategy based on vast experience in the hydrocephalus management at a single institution. The need for the diagnostic laboratory testing, age and presentation based radiological imaging, significance of neuro-opthalmological exam, and when to consider the emergent exploration have been discussed in detail. Moreover, a definitive triaging strategy has been described with the help of flow chart diagrams for clinicians, and the neurosurgeons in practice. The triage starts from detail history, physical exam, necessary labs, radiological imaging depending on the presentation, and the age of the child. A quick head CT scan helps after shunt surgery while, a FAST sequence MRI scan (fsMRI) is important in post ETV patients. The need for neuro-opthalmological exam, and the shunt series stays vital in asymptomatic patients during regular follow up. Copyright © 2017 Elsevier Ltd. All rights reserved.

  9. Identifying Coherent Structures in a 3-Stream Supersonic Jet Flow using Time-Resolved Schlieren Imaging

    NASA Astrophysics Data System (ADS)

    Tenney, Andrew; Coleman, Thomas; Berry, Matthew; Magstadt, Andy; Gogineni, Sivaram; Kiel, Barry

    2015-11-01

    Shock cells and large scale structures present in a three-stream non-axisymmetric jet are studied both qualitatively and quantitatively. Large Eddy Simulation is utilized first to gain an understanding of the underlying physics of the flow and direct the focus of the physical experiment. The flow in the experiment is visualized using long exposure Schlieren photography, with time resolved Schlieren photography also a possibility. Velocity derivative diagnostics are calculated from the grey-scale Schlieren images are analyzed using continuous wavelet transforms. Pressure signals are also captured in the near-field of the jet to correlate with the velocity derivative diagnostics and assist in unraveling this complex flow. We acknowledge the support of AFRL through an SBIR grant.

  10. Developments in the simulation of compressible inviscid and viscous flow on supercomputers

    NASA Technical Reports Server (NTRS)

    Steger, J. L.; Buning, P. G.

    1985-01-01

    In anticipation of future supercomputers, finite difference codes are rapidly being extended to simulate three-dimensional compressible flow about complex configurations. Some of these developments are reviewed. The importance of computational flow visualization and diagnostic methods to three-dimensional flow simulation is also briefly discussed.

  11. (18)F-FDG uptake predicts diagnostic yield of transbronchial biopsy in peripheral lung cancer.

    PubMed

    Umeda, Yukihiro; Demura, Yoshiki; Anzai, Masaki; Matsuoka, Hiroki; Araya, Tomoyuki; Nishitsuji, Masaru; Nishi, Koichi; Tsuchida, Tatsuro; Sumida, Yasuyuki; Morikawa, Miwa; Ameshima, Shingo; Ishizaki, Takeshi; Kasahara, Kazuo; Ishizuka, Tamotsu

    2014-07-01

    Recent advances in endobronchial ultrasonography with a guide sheath (EBUS-GS) have enabled better visualization of distal airways, while virtual bronchoscopic navigation (VBN) has been shown useful as a guide to navigate the bronchoscope. However, indications for utilizing VBN and EBUS-GS are not always clear. To clarify indications for a bronchoscopic examination using VBN and EBUS-GS, we evaluated factors that predict the diagnostic yield of a transbronchial biopsy (TBB) procedure for peripheral lung cancer (PLC) lesions. We retrospectively reviewed the charts of 194 patients with 201 PLC lesions (≤3cm mean diameter), and analyzed the association of diagnostic yield of TBB with [(18)F]-fluoro-2-deoxy-d-glucose ((18)F-FDG) positron emission tomography and chest computed tomography (CT) findings. The diagnostic yield of TBB using VBN and EBUS-GS was 66.7%. High maximum standardized uptake value (SUVmax), positive bronchus sign, and ground-glass opacity component shown on CT were all significant predictors of diagnostic yield, while multivariate analysis showed only high (18)F-FDG uptake (SUVmax ≥2.8) and positive bronchus sign as significant predictors. Diagnostic yield was higher for PLC lesions with high (18)F-FDG uptake (SUVmax ≥2.8) and positive bronchus sign (84.6%) than for those with SUVmax <2.8 and negative bronchus sign (33.3%). High (18)F-FDG uptake was also correlated with tumor invasiveness. High (18)F-FDG uptake predicted the diagnostic yield of TBB using VBN and EBUS-GS for PLC lesions. (18)F-FDG uptake and bronchus sign may indicate for the accurate application of bronchoscopy with those modalities for diagnosing PLC. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

  12. Variation in Results Release and Patient Portal Access to Diagnostic Test Results at an Academic Medical Center

    PubMed Central

    Krasowski, Matthew D.; Grieme, Caleb V.; Cassady, Brian; Dreyer, Nicholas R.; Wanat, Karolyn A.; Hightower, Maia; Nepple, Kenneth G.

    2017-01-01

    Background: Electronic health records (EHRs) are commonplace in industrialized countries. Many hospitals are granting their patients access to their medical information through online patient portals. In this report, we describe a retrospective analysis of patient access to diagnostic test results released through the patient portal (MyChart; Epic, Inc.) at a state academic medical center. Methods: We analyzed 6 months of data for anatomic pathology, clinical laboratory, and radiology test results to evaluate variations in results release (automated vs. manual) and subsequent patient access to the institutional patient portal. During this period, diagnostic test results were released for all patient encounters including inpatient units, outpatient clinics, and the emergency department. Results: Manual results release by providers before automated release time occurred most commonly in the outpatient setting. The highest rates of access of diagnostic test results occurred for outpatients (about 30% overall view rate), females (two times or more compared to males in nearly every age bracket), and 20–45-year-old. Access rates of diagnostic tests in the emergency department or inpatient units were <10% across all populations. Access of diagnostic test results was very low for 12–17-year-old, likely influenced by institutional policies limiting parental proxy access within this pediatric age range. Approximately 20% of outpatient laboratory results were viewed by patients within 8 h of release from the EHR to the patient portal and 10% within 2 h of release. Conclusions: Patient accessing of diagnostic test results were generally higher for females, outpatients, and 20–45-year-old. Approximately, 20% of outpatient results were viewed quickly by patients after release to the EHR. PMID:29226008

  13. Variation in Results Release and Patient Portal Access to Diagnostic Test Results at an Academic Medical Center.

    PubMed

    Krasowski, Matthew D; Grieme, Caleb V; Cassady, Brian; Dreyer, Nicholas R; Wanat, Karolyn A; Hightower, Maia; Nepple, Kenneth G

    2017-01-01

    Electronic health records (EHRs) are commonplace in industrialized countries. Many hospitals are granting their patients access to their medical information through online patient portals. In this report, we describe a retrospective analysis of patient access to diagnostic test results released through the patient portal (MyChart; Epic, Inc.) at a state academic medical center. We analyzed 6 months of data for anatomic pathology, clinical laboratory, and radiology test results to evaluate variations in results release (automated vs. manual) and subsequent patient access to the institutional patient portal. During this period, diagnostic test results were released for all patient encounters including inpatient units, outpatient clinics, and the emergency department. Manual results release by providers before automated release time occurred most commonly in the outpatient setting. The highest rates of access of diagnostic test results occurred for outpatients (about 30% overall view rate), females (two times or more compared to males in nearly every age bracket), and 20-45-year-old. Access rates of diagnostic tests in the emergency department or inpatient units were <10% across all populations. Access of diagnostic test results was very low for 12-17-year-old, likely influenced by institutional policies limiting parental proxy access within this pediatric age range. Approximately 20% of outpatient laboratory results were viewed by patients within 8 h of release from the EHR to the patient portal and 10% within 2 h of release. Patient accessing of diagnostic test results were generally higher for females, outpatients, and 20-45-year-old. Approximately, 20% of outpatient results were viewed quickly by patients after release to the EHR.

  14. Dually diagnosed: a retrospective study of the process of diagnosing autism spectrum disorders in children who are deaf and hard of hearing.

    PubMed

    Szarkowski, Amy; Flynn, Suzanne; Clark, Terrell

    2014-11-01

    Utilizing a retrospective chart review of 30 children who have been dually diagnosed with hearing loss and autism spectrum disorders (ASDs), this study explores the process of arriving at the diagnosis of ASD in this population. Factors of interest include the age of ASD diagnosis in children who are deaf and hard of hearing, the types of professionals involved in making the diagnosis, and the measures used for assessment. Complications in the diagnostic process are highlighted. Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

  15. Stefan blowing effects on MHD bioconvection flow of a nanofluid in the presence of gyrotactic microorganisms with active and passive nanoparticles flux

    NASA Astrophysics Data System (ADS)

    Giri, Shib Sankar; Das, Kalidas; Kundu, Prabir Kumar

    2017-02-01

    The present paper investigates the effect of Stefan blowing on the hydro-magnetic bioconvection of a water-based nanofluid flow containing gyrotactic microorganisms through a permeable surface. Also we studied both actively and passively the controlled flux of nanoparticles and the effect of a surface slip at the wall. We adopt a similarity approach to reduce the leading partial differential equations into ordinary differential equations along with two separate boundary conditions (active and passive) and solve the resulting equations numerically by employing the RK-4 method through the shooting technique to perform the flow analysis. Discussions on the effect of emerging flow parameter on the flow characteristic are made properly through graphs and charts. We observed that the effects of the traditional Lewis number and suction/blowing parameter on temperature distribution and microorganism concentration are converse to each other. A fair result comparison of the present paper with formerly obtained results is given.

  16. Manufacturing Methods and Technology Project Summary Reports

    DTIC Science & Technology

    1982-06-01

    Effect Cathode SUMMARY Many of the problems associated with the processes shown in the process flow chart. Figure 2, were solved. The stress that...presence of this tape provides stress points in the encapsulant and can cause it to crack under thermal cycling, creates the possibility of...observed at the inner bore ^P diameter, confirming stresses in excess of the material yield strength at the highest speeds. Based upon these

  17. An on-line system for hand-printed input

    NASA Technical Reports Server (NTRS)

    Williams, T. G.; Bebb, J.

    1971-01-01

    The capability of graphic input/output systems is described. Topics considered are a character recognizer and dictionary building program, an initial flow chart element input program, and a system entitled The Assistant Mathematician, which uses ordinary mathematics to specify numeric computation. All three parts are necessary to allow a user to carry on a mathematical dialogue with the computer in the language and notation of his discipline or problem domain.

  18. Logic Models in Out-of-School Time Programs: What Are They and Why Are They Important? Research-to-Results Brief. Publication #2007-01

    ERIC Educational Resources Information Center

    Hamilton, Jenny; Bronte-Tinkew, Jacinta

    2007-01-01

    A logic model, also called a conceptual model and theory-of-change model, is a visual representation of how a program is expected to "work." It relates resources, activities, and the intended changes or impacts that a program is expected to create. Typically, logic models are diagrams or flow charts with illustrations, text, and arrows that…

  19. Seeing the Enemy: Army Air Force Aerial Reconnaissance Support to U.S. Army Operations in the Mediterranean in World War 2

    DTIC Science & Technology

    2009-06-12

    Mission Debrief Report ................................157 Figure 41. Flow Chart of Film from Collection to Division...reconnaissance increased speed, but the limited analysis sacrificed accuracy and detail, and caused intelligence personnel and commanders dilemmas...targets or larger areas for general familiarization or map-making. This detail had a price: timeliness. Early in the war, film development and print

  20. Documentation of the Fourth Order Band Model

    NASA Technical Reports Server (NTRS)

    Kalnay-Rivas, E.; Hoitsma, D.

    1979-01-01

    A general circulation model is presented which uses quadratically conservative, fourth order horizontal space differences on an unstaggered grid and second order vertical space differences with a forward-backward or a smooth leap frog time scheme to solve the primitive equations of motion. The dynamic equations for motion, finite difference equations, a discussion of the structure and flow chart of the program code, a program listing, and three relevent papers are given.

  1. Essentials of clinical immunology

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Chapel, M.A.; Haeney, M.

    1988-01-01

    The authors demonstrate that clinical immunology is a subject which is useful for the diagnosis and management of a great number and variety of human diseases. The book makes use of illustrative case histories and flow charts to demonstrate the usefulness of clinical immunology in the diagnosis and management of a great number and variety of human diseases. The authors discuss the relevance of new DNA technology and the role of bone marrow transplantation.

  2. Evaluation of engineering foods for Controlled Ecological Life Support Systems (CELSS)

    NASA Technical Reports Server (NTRS)

    Karel, M.

    1982-01-01

    The feasibility of developing acceptable and reliable engineered foods for use in controlled ecological support systems (CELSS) was evaluated. Food resupply and regeneration are calculated, flow charts of food processes in a multipurpose food pilot plant are presented, and equipment for a multipurpose food pilot plant and potential simplification of processes are discussed. Food-waste treatment and water usage in food processing and preparation are also considered.

  3. Synthetic-Type Control Charts for Time-Between-Events Monitoring

    PubMed Central

    Yen, Fang Yen; Chong, Khoo Michael Boon; Ha, Lee Ming

    2013-01-01

    This paper proposes three synthetic-type control charts to monitor the mean time-between-events of a homogenous Poisson process. The first proposed chart combines an Erlang (cumulative time between events, Tr) chart and a conforming run length (CRL) chart, denoted as Synth-Tr chart. The second proposed chart combines an exponential (or T) chart and a group conforming run length (GCRL) chart, denoted as GR-T chart. The third proposed chart combines an Erlang chart and a GCRL chart, denoted as GR-Tr chart. By using a Markov chain approach, the zero- and steady-state average number of observations to signal (ANOS) of the proposed charts are obtained, in order to evaluate the performance of the three charts. The optimal design of the proposed charts is shown in this paper. The proposed charts are superior to the existing T chart, Tr chart, and Synth-T chart. As compared to the EWMA-T chart, the GR-T chart performs better in detecting large shifts, in terms of the zero- and steady-state performances. The zero-state Synth-T4 and GR-Tr (r = 3 or 4) charts outperform the EWMA-T chart for all shifts, whereas the Synth-Tr (r = 2 or 3) and GR-T 2 charts perform better for moderate to large shifts. For the steady-state process, the Synth-Tr and GR-Tr charts are more efficient than the EWMA-T chart in detecting small to moderate shifts. PMID:23755231

  4. Operations management tools to be applied for textile

    NASA Astrophysics Data System (ADS)

    Maralcan, A.; Ilhan, I.

    2017-10-01

    In this paper, basic concepts of process analysis such as flow time, inventory, bottleneck, labour cost and utilization are illustrated first. The effect of bottleneck on the results of a business are especially emphasized. In the next section, tools on productivity measurement; KPI (Key Performance Indicators) Tree, OEE (Overall Equipment Effectiveness) and Takt Time are introduced and exemplified. KPI tree is a diagram on which we can visualize all the variables of an operation which are driving financial results through cost and profit. OEE is a tool to measure a potential extra capacity of an equipment or an employee. Takt time is a tool to determine the process flow rate according to the customer demand. KPI tree is studied through the whole process while OEE is exemplified for a stenter frame machine which is the most important machine (and usually the bottleneck) and the most expensive investment in a finishing plant. Takt time is exemplified for the quality control department. Finally quality tools, six sigma, control charts and jidoka are introduced. Six sigma is a tool to measure process capability and by the way probability of a defect. Control chart is a powerful tool to monitor the process. The idea of jidoka (detect, stop and alert) is about alerting the people that there is a problem in the process.

  5. Validation of structural analysis methods using the in-house liner cyclic rigs

    NASA Technical Reports Server (NTRS)

    Thompson, R. L.

    1982-01-01

    Test conditions and variables to be considered in each of the test rigs and test configurations, and also used in the validation of the structural predictive theories and tools, include: thermal and mechanical load histories (simulating an engine mission cycle; different boundary conditions; specimens and components of different dimensions and geometries; different materials; various cooling schemes and cooling hole configurations; several advanced burner liner structural design concepts; and the simulation of hot streaks. Based on these test conditions and test variables, the test matrices for each rig and configurations can be established to verify the predictive tools over as wide a range of test conditions as possible using the simplest possible tests. A flow chart for the thermal/structural analysis of a burner liner and how the analysis relates to the tests is shown schematically. The chart shows that several nonlinear constitutive theories are to be evaluated.

  6. Spatio-temporal alignment of multiple sensors

    NASA Astrophysics Data System (ADS)

    Zhang, Tinghua; Ni, Guoqiang; Fan, Guihua; Sun, Huayan; Yang, Biao

    2018-01-01

    Aiming to achieve the spatio-temporal alignment of multi sensor on the same platform for space target observation, a joint spatio-temporal alignment method is proposed. To calibrate the parameters and measure the attitude of cameras, an astronomical calibration method is proposed based on star chart simulation and collinear invariant features of quadrilateral diagonal between the observed star chart. In order to satisfy a temporal correspondence and spatial alignment similarity simultaneously, the method based on the astronomical calibration and attitude measurement in this paper formulates the video alignment to fold the spatial and temporal alignment into a joint alignment framework. The advantage of this method is reinforced by exploiting the similarities and prior knowledge of velocity vector field between adjacent frames, which is calculated by the SIFT Flow algorithm. The proposed method provides the highest spatio-temporal alignment accuracy compared to the state-of-the-art methods on sequences recorded from multi sensor at different times.

  7. A feasability study of color flow doppler vectorization for automated blood flow monitoring.

    PubMed

    Schorer, R; Badoual, A; Bastide, B; Vandebrouck, A; Licker, M; Sage, D

    2017-12-01

    An ongoing issue in vascular medicine is the measure of the blood flow. Catheterization remains the gold standard measurement method, although non-invasive techniques are an area of intense research. We hereby present a computational method for real-time measurement of the blood flow from color flow Doppler data, with a focus on simplicity and monitoring instead of diagnostics. We then analyze the performance of a proof-of-principle software implementation. We imagined a geometrical model geared towards blood flow computation from a color flow Doppler signal, and we developed a software implementation requiring only a standard diagnostic ultrasound device. Detection performance was evaluated by computing flow and its determinants (flow speed, vessel area, and ultrasound beam angle of incidence) on purposely designed synthetic and phantom-based arterial flow simulations. Flow was appropriately detected in all cases. Errors on synthetic images ranged from nonexistent to substantial depending on experimental conditions. Mean errors on measurements from our phantom flow simulation ranged from 1.2 to 40.2% for angle estimation, and from 3.2 to 25.3% for real-time flow estimation. This study is a proof of concept showing that accurate measurement can be done from automated color flow Doppler signal extraction, providing the industry the opportunity for further optimization using raw ultrasound data.

  8. Use of electronic data and existing screening tools to identify clinically significant obstructive sleep apnea.

    PubMed

    Severson, Carl A; Pendharkar, Sachin R; Ronksley, Paul E; Tsai, Willis H

    2015-01-01

    To assess the ability of electronic health data and existing screening tools to identify clinically significant obstructive sleep apnea (OSA), as defined by symptomatic or severe OSA. The present retrospective cohort study of 1041 patients referred for sleep diagnostic testing was undertaken at a tertiary sleep centre in Calgary, Alberta. A diagnosis of clinically significant OSA or an alternative sleep diagnosis was assigned to each patient through blinded independent chart review by two sleep physicians. Predictive variables were identified from online questionnaire data, and diagnostic algorithms were developed. The performance of electronically derived algorithms for identifying patients with clinically significant OSA was determined. Diagnostic performance of these algorithms was compared with versions of the STOP-Bang questionnaire and adjusted neck circumference score (ANC) derived from electronic data. Electronic questionnaire data were highly sensitive (>95%) at identifying clinically significant OSA, but not specific. Sleep diagnostic testing-determined respiratory disturbance index was very specific (specificity ≥95%) for clinically relevant disease, but not sensitive (<35%). Derived algorithms had similar accuracy to the STOP-Bang or ANC, but required fewer questions and calculations. These data suggest that a two-step process using a small number of clinical variables (maximizing sensitivity) and objective diagnostic testing (maximizing specificity) is required to identify clinically significant OSA. When used in an online setting, simple algorithms can identify clinically relevant OSA with similar performance to existing decision rules such as the STOP-Bang or ANC.

  9. Feasibility of streamlining an interactive Bayesian-based diagnostic support tool designed for clinical practice

    NASA Astrophysics Data System (ADS)

    Chen, Po-Hao; Botzolakis, Emmanuel; Mohan, Suyash; Bryan, R. N.; Cook, Tessa

    2016-03-01

    In radiology, diagnostic errors occur either through the failure of detection or incorrect interpretation. Errors are estimated to occur in 30-35% of all exams and contribute to 40-54% of medical malpractice litigations. In this work, we focus on reducing incorrect interpretation of known imaging features. Existing literature categorizes cognitive bias leading a radiologist to an incorrect diagnosis despite having correctly recognized the abnormal imaging features: anchoring bias, framing effect, availability bias, and premature closure. Computational methods make a unique contribution, as they do not exhibit the same cognitive biases as a human. Bayesian networks formalize the diagnostic process. They modify pre-test diagnostic probabilities using clinical and imaging features, arriving at a post-test probability for each possible diagnosis. To translate Bayesian networks to clinical practice, we implemented an entirely web-based open-source software tool. In this tool, the radiologist first selects a network of choice (e.g. basal ganglia). Then, large, clearly labeled buttons displaying salient imaging features are displayed on the screen serving both as a checklist and for input. As the radiologist inputs the value of an extracted imaging feature, the conditional probabilities of each possible diagnosis are updated. The software presents its level of diagnostic discrimination using a Pareto distribution chart, updated with each additional imaging feature. Active collaboration with the clinical radiologist is a feasible approach to software design and leads to design decisions closely coupling the complex mathematics of conditional probability in Bayesian networks with practice.

  10. A differentially expressed set of microRNAs in cerebro-spinal fluid (CSF) can diagnose CNS malignancies

    PubMed Central

    Drusco, Alessandra; Bottoni, Arianna; Laganà, Alessandro; Acunzo, Mario; Fassan, Matteo; Cascione, Luciano; Antenucci, Anna; Kumchala, Prasanthi; Vicentini, Caterina; Gardiman, Marina P.; Alder, Hansjuerg; Carosi, Mariantonia A.; Ammirati, Mario; Gherardi, Stefano; Luscrì, Marilena; Carapella, Carmine; Zanesi, Nicola; Croce, Carlo M.

    2015-01-01

    Central Nervous System malignancies often require stereotactic biopsy or biopsy for differential diagnosis, and for tumor staging and grading. Furthermore, stereotactic biopsy can be non-diagnostic or underestimate grading. Hence, there is a compelling need of new diagnostic biomarkers to avoid such invasive procedures. Several biological markers have been proposed, but they can only identify specific prognostic subtype of Central Nervous System tumors, and none of them has found a standardized clinical application. The aim of the study was to identify a Cerebro-Spinal Fluid microRNA signature that could differentiate among Central Nervous System malignancies. CSF total RNA of 34 neoplastic and of 14 non-diseased patients was processed by NanoString. Comparison among groups (Normal, Benign, Glioblastoma, Medulloblastoma, Metastasis and Lymphoma) lead to the identification of a microRNA profile that was further confirmed by RT-PCR and in situ hybridization. Hsa-miR-451, -711, 935, -223 and -125b were significantly differentially expressed among the above mentioned groups, allowing us to draw an hypothetical diagnostic chart for Central Nervous System malignancies. This is the first study to employ the NanoString technique for Cerebro-Spinal Fluid microRNA profiling. In this article, we demonstrated that Cerebro-Spinal Fluid microRNA profiling mirrors Central Nervous System physiologic or pathologic conditions. Although more cases need to be tested, we identified a diagnostic Cerebro-Spinal Fluid microRNA signature with good perspectives for future diagnostic clinical applications. PMID:26246487

  11. Causes of recurrent pneumonia in children in a general hospital.

    PubMed

    Hoving, M F Paulien; Brand, Paul L P

    2013-03-01

    Because the few previous studies on underlying causes of recurrent pneumonia in children have come from tertiary care referral centres where selection bias may be important, the aim of this study was to examine underlying causes of recurrent pneumonia in children in a general hospital. We performed a retrospective chart review in a general hospital of 62 children with recurrent pneumonia over a 7.5 years period. In 19 patients (30.6%), no cause was identified, commonly because favourable natural history obviated the need for a full and invasive diagnostic work-up. Other underlying causes included recurrent aspiration in 16 patients (25.7%), lung disease (airway stenosis, bronchiectasis, middle lobe syndrome or tracheooesophageal fistula) in 10 patients (16.1%) and immune deficiency in 10 patients (16.1%). In contrast to previous studies, asthma was never diagnosed as an underlying cause, but diagnostic confusion between asthma (or recurrent upper respiratory tract infections) and recurrent pneumonia was common. The cause of recurrent pneumonia in children remains elusive in almost a third of patients, partly because the favourable natural history consistent with immune system maturation eliminates the need for further diagnostic procedures. Asthma is more likely a differential diagnostic consideration than an underlying cause of recurrent pneumonia in children. A standardised diagnostic guideline is needed to improve knowledge on causes of recurrent pneumonia in children. © 2013 The Authors. Journal of Paediatrics and Child Health © 2013 Paediatrics and Child Health Division (Royal Australasian College of Physicians).

  12. A differentially expressed set of microRNAs in cerebro-spinal fluid (CSF) can diagnose CNS malignancies.

    PubMed

    Drusco, Alessandra; Bottoni, Arianna; Laganà, Alessandro; Acunzo, Mario; Fassan, Matteo; Cascione, Luciano; Antenucci, Anna; Kumchala, Prasanthi; Vicentini, Caterina; Gardiman, Marina P; Alder, Hansjuerg; Carosi, Mariantonia A; Ammirati, Mario; Gherardi, Stefano; Luscrì, Marilena; Carapella, Carmine; Zanesi, Nicola; Croce, Carlo M

    2015-08-28

    Central Nervous System malignancies often require stereotactic biopsy or biopsy for differential diagnosis, and for tumor staging and grading. Furthermore, stereotactic biopsy can be non-diagnostic or underestimate grading. Hence, there is a compelling need of new diagnostic biomarkers to avoid such invasive procedures. Several biological markers have been proposed, but they can only identify specific prognostic subtype of Central Nervous System tumors, and none of them has found a standardized clinical application.The aim of the study was to identify a Cerebro-Spinal Fluid microRNA signature that could differentiate among Central Nervous System malignancies.CSF total RNA of 34 neoplastic and of 14 non-diseased patients was processed by NanoString. Comparison among groups (Normal, Benign, Glioblastoma, Medulloblastoma, Metastasis and Lymphoma) lead to the identification of a microRNA profile that was further confirmed by RT-PCR and in situ hybridization.Hsa-miR-451, -711, 935, -223 and -125b were significantly differentially expressed among the above mentioned groups, allowing us to draw an hypothetical diagnostic chart for Central Nervous System malignancies.This is the first study to employ the NanoString technique for Cerebro-Spinal Fluid microRNA profiling. In this article, we demonstrated that Cerebro-Spinal Fluid microRNA profiling mirrors Central Nervous System physiologic or pathologic conditions. Although more cases need to be tested, we identified a diagnostic Cerebro-Spinal Fluid microRNA signature with good perspectives for future diagnostic clinical applications.

  13. Communication gaps in nursing home transfers to the ED: impact on turnaround time, disposition, and diagnostic testing.

    PubMed

    Nelson, Drew; Washton, Danae; Jeanmonod, Rebecca

    2013-04-01

    This study aims to determine the source of communication gaps in history of present illness (HPI), medical history, and advanced directives in nursing home (NH) patients transferred to the emergency department (ED). We also attempt to determine if these gaps create differences in patient turnaround time (TAT), disposition decision, or diagnostic testing. A convenience sample of patients transferred from NHs to a level 1 community trauma center was enrolled by the physicians caring for them. The physicians assessed the adequacy and source of the history for each patient. The patient's chart was then retrospectively reviewed to determine disposition, ED TAT, and diagnostic tests ordered. One hundred patients were enrolled. Physicians found that NH paperwork contained adequate HPI 35% of the time. Patients could provide their own HPI 28% of the time. In 32% of patients, adequate HPI could not be obtained from the patient, NH paperwork, or NH personnel. Comparing patients in whom adequate HPI was available (n = 68) to those in whom HPI was not available (n = 32), there was no difference in TAT (146 vs 173 minutes, P = .22), admissions (60% vs 66%, P = .66), or diagnostic testing (P = .89-1.0). Emergency department physicians often do not have adequate HPI in patients transferred from NHs. The absence of adequate information does not affect patient TAT, disposition decision, or ED diagnostic testing. Copyright © 2013 Elsevier Inc. All rights reserved.

  14. Laser-plasma interaction experiments and diagnostics at NRL (Naval Research Laboratory). Memorandum report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ripin, B.H.; Grun, J.; Herbst, M.J.

    Laser plasma interaction experiments have now advanced to the point where very quantitative measurements are required to elucidate the physic issues important for laser fusion and other applications. Detailed time-resolved knowledge of the plasma density, temperature, velocity gradients, spatial structure, heat flow characteristics, radiation emission, etc, are needed over tremendou ranges of plasma density and temperature. Moreover, the time scales are very short, aggrevating the difficulty of the measurements further. Nonetheless, such substantial progress has been made in diagnostic development during the past few years that we are now able to do well diagnosed experiments. In this paper the authorsmore » review recent diagnostic developments for laser-plasma interactions, outline their regimes of applicability, and show examples of their utility. In addition to diagnostics for the high densities and temperature characteristic of laser fusion physics studies, diagnostics designed to study the two-stream interactions of laser created plasma flowing through an ambient low density plasma will be described.« less

  15. SPECT Myocardial Blood Flow Quantitation Concludes Equivocal Myocardial Perfusion SPECT Studies to Increase Diagnostic Benefits.

    PubMed

    Chen, Lung-Ching; Lin, Chih-Yuan; Chen, Ing-Jou; Ku, Chi-Tai; Chen, Yen-Kung; Hsu, Bailing

    2016-01-01

    Recently, myocardial blood flow quantitation with dynamic SPECT/CT has been reported to enhance the detection of coronary artery disease in human. This advance has created important clinical applications to coronary artery disease diagnosis and management for areas where myocardial perfusion PET tracers are not available. We present 2 clinical cases that undergone a combined test of 1-day rest/dipyridamole-stress dynamic SPECT and ECG-gated myocardial perfusion SPECT scans using an integrated imaging protocol and demonstrate that flow parameters are capable to conclude equivocal myocardial perfusion SPECT studies, therefore increasing diagnostic benefits to add value in making clinical decisions.

  16. 21 CFR 876.1800 - Urine flow or volume measuring system.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 8 2012-04-01 2012-04-01 false Urine flow or volume measuring system. 876.1800... (CONTINUED) MEDICAL DEVICES GASTROENTEROLOGY-UROLOGY DEVICES Diagnostic Devices § 876.1800 Urine flow or volume measuring system. (a) Identification. A urine flow or volume measuring system is a device that...

  17. 21 CFR 876.1800 - Urine flow or volume measuring system.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 8 2014-04-01 2014-04-01 false Urine flow or volume measuring system. 876.1800... (CONTINUED) MEDICAL DEVICES GASTROENTEROLOGY-UROLOGY DEVICES Diagnostic Devices § 876.1800 Urine flow or volume measuring system. (a) Identification. A urine flow or volume measuring system is a device that...

  18. 21 CFR 876.1800 - Urine flow or volume measuring system.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 8 2013-04-01 2013-04-01 false Urine flow or volume measuring system. 876.1800... (CONTINUED) MEDICAL DEVICES GASTROENTEROLOGY-UROLOGY DEVICES Diagnostic Devices § 876.1800 Urine flow or volume measuring system. (a) Identification. A urine flow or volume measuring system is a device that...

  19. 21 CFR 876.1800 - Urine flow or volume measuring system.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 8 2011-04-01 2011-04-01 false Urine flow or volume measuring system. 876.1800... (CONTINUED) MEDICAL DEVICES GASTROENTEROLOGY-UROLOGY DEVICES Diagnostic Devices § 876.1800 Urine flow or volume measuring system. (a) Identification. A urine flow or volume measuring system is a device that...

  20. Critical evaluation of reverse engineering tool Imagix 4D!

    PubMed

    Yadav, Rashmi; Patel, Ravindra; Kothari, Abhay

    2016-01-01

    The comprehension of legacy codes is difficult to understand. Various commercial reengineering tools are available that have unique working styles, and are equipped with their inherent capabilities and shortcomings. The focus of the available tools is in visualizing static behavior not the dynamic one. Therefore, it is difficult for people who work in software product maintenance, code understanding reengineering/reverse engineering. Consequently, the need for a comprehensive reengineering/reverse engineering tool arises. We found the usage of Imagix 4D to be good as it generates the maximum pictorial representations in the form of flow charts, flow graphs, class diagrams, metrics and, to a partial extent, dynamic visualizations. We evaluated Imagix 4D with the help of a case study involving a few samples of source code. The behavior of the tool was analyzed on multiple small codes and a large code gcc C parser. Large code evaluation was performed to uncover dead code, unstructured code, and the effect of not including required files at preprocessing level. The utility of Imagix 4D to prepare decision density and complexity metrics for a large code was found to be useful in getting to know how much reengineering is required. At the outset, Imagix 4D offered limitations in dynamic visualizations, flow chart separation (large code) and parsing loops. The outcome of evaluation will eventually help in upgrading Imagix 4D and posed a need of full featured tools in the area of software reengineering/reverse engineering. It will also help the research community, especially those who are interested in the realm of software reengineering tool building.

  1. Fractional flow reserve-guided management in stable coronary disease and acute myocardial infarction: recent developments

    PubMed Central

    Berry, Colin; Corcoran, David; Hennigan, Barry; Watkins, Stuart; Layland, Jamie; Oldroyd, Keith G.

    2015-01-01

    Coronary artery disease (CAD) is a leading global cause of morbidity and mortality, and improvements in the diagnosis and treatment of CAD can reduce the health and economic burden of this condition. Fractional flow reserve (FFR) is an evidence-based diagnostic test of the physiological significance of a coronary artery stenosis. Fractional flow reserve is a pressure-derived index of the maximal achievable myocardial blood flow in the presence of an epicardial coronary stenosis as a ratio to maximum achievable flow if that artery were normal. When compared with standard angiography-guided management, FFR disclosure is impactful on the decision for revascularization and clinical outcomes. In this article, we review recent developments with FFR in patients with stable CAD and recent myocardial infarction. Specifically, we review novel developments in our understanding of CAD pathophysiology, diagnostic applications, prognostic studies, clinical trials, and clinical guidelines. PMID:26038588

  2. Diagnostic overshadowing in a population of children with neurological disabilities: A cross sectional descriptive study on acquired ADHD.

    PubMed

    Hendriksen, J G M; Peijnenborgh, J C A W; Aldenkamp, A P; Vles, J S H

    2015-09-01

    Diagnostic overshadowing refers to the underdiagnosis of comorbid conditions in children with known neurological diagnoses. To demonstrate diagnostic overshadowing we determined the prevalence of attention deficit-hyperactivity disorders (ADHD) in a cohort of children with a wide range of neurological disabilities. The study cohort consisted of 685 children (mean age 10.3 years, SD: 3.1; 425 boys and 260 girls) who visited a tertiary outpatient multidisciplinary clinic for neurological learning disabilities. Patients with ADHD were identified by retrospective chart review using DSM-IV criteria. The prevalence of ADHD in this cohort was 38.8% (266 children); of these children only 28.2% (75 children) were diagnosed with ADHD before referral. ADHD is a common problem in children with neurological disabilities and may be underdiagnosed due to overshadowing of somatic, physical or syndromal features of the disability. In our heterogeneous population ADHD was overshadowed in 71.8% of the cases. This finding may have important implications for diagnosis and treatment of mental health needs in children with neurological disabilities. Copyright © 2015 European Paediatric Neurology Society. Published by Elsevier Ltd. All rights reserved.

  3. Aerophagia in children: characterization of a functional gastrointestinal disorder.

    PubMed

    Chitkara, D K; Bredenoord, A J; Bredenood, A J; Wang, M; Rucker, M J; Talley, N J

    2005-08-01

    The purpose of this study was to describe presenting symptoms, diagnostic testing, treatments and outcomes in a group of children with a diagnosis of aerophagia. A computerized diagnostic index was used to identify all children between the age of 1 and 17 years diagnosed with aerophagia at a tertiary care medical centre between 1975 and 2003. Individual medical charts were abstracted for information on the demographics, clinical features, co-morbid diagnoses, diagnostic work up and treatment of children with aerophagia. Information on presenting symptoms was also collected for a group of children who were retrospectively classified as having functional dyspepsia for comparison (n = 40). Forty-five children had a diagnosis of aerophagia. The mean duration of symptoms in children with aerophagia was 16 +/- 5 months. The most common gastrointestinal symptoms were abdominal pain, distention and frequent belching. Children with functional dyspepsia had a higher prevalence of nausea, vomiting, abdominal pain and unintentional weight loss compared to children with aerophagia (all P < 0.05). In conclusion, aerophagia is a disorder that is diagnosed in neurologically normal males and females, who can experience prolonged symptoms. Although many children with aerophagia present with upper gastrointestinal symptoms, the disorder appears to be distinct from functional dyspepsia.

  4. A Novel Field-Deployable Point-of-Care Diagnostic Test for Cutaneous Leishmaniasis

    DTIC Science & Technology

    2017-10-01

    AWARD NUMBER: W81XWH-14-2-0195 TITLE: A Novel Field-Deployable Point-of-Care Diagnostic Test for Cutaneous Leishmaniasis PRINCIPAL INVESTIGATOR...Field-Deployable Point-of-Care Diagnostic Test for Cutaneous Leishmaniasis 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S...Month % completion Aim 1: To use simulated field conditions to optimize and produce the established RPA lateral flow diagnostic test for POC

  5. The Role of Radiology in the Diagnostic Process: Information, Communication, and Teamwork.

    PubMed

    Larson, David B; Langlotz, Curtis P

    2017-11-01

    The diagnostic radiology process represents a partnership between clinical and radiology teams. As such, breakdowns in interpersonal interactions and communication can result in patient harm. We explore the role of radiology in the diagnostic process, focusing on key concepts of information and communication, as well as key interpersonal interactions of teamwork, collaboration, and collegiality, all based on trust. We propose 10 principles to facilitate effective information flow in the diagnostic process.

  6. Modeling Combustion in Supersonic Flows

    NASA Technical Reports Server (NTRS)

    Drummond, J. Philip; Danehy, Paul M.; Bivolaru, Daniel; Gaffney, Richard L.; Tedder, Sarah A.; Cutler, Andrew D.

    2007-01-01

    This paper discusses the progress of work to model high-speed supersonic reacting flow. The purpose of the work is to improve the state of the art of CFD capabilities for predicting the flow in high-speed propulsion systems, particularly combustor flow-paths. The program has several components including the development of advanced algorithms and models for simulating engine flowpaths as well as a fundamental experimental and diagnostic development effort to support the formulation and validation of the mathematical models. The paper will provide details of current work on experiments that will provide data for the modeling efforts along with with the associated nonintrusive diagnostics used to collect the data from the experimental flowfield. Simulation of a recent experiment to partially validate the accuracy of a combustion code is also described.

  7. Diagnosing collisions of magnetized, high energy density plasma flows using a combination of collective Thomson scattering, Faraday rotation, and interferometry (invited)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Swadling, G. F., E-mail: swadling@imperial.ac.uk; Lebedev, S. V.; Hall, G. N.

    2014-11-15

    A suite of laser based diagnostics is used to study interactions of magnetised, supersonic, radiatively cooled plasma flows produced using the Magpie pulse power generator (1.4 MA, 240 ns rise time). Collective optical Thomson scattering measures the time-resolved local flow velocity and temperature across 7–14 spatial positions. The scattering spectrum is recorded from multiple directions, allowing more accurate reconstruction of the flow velocity vectors. The areal electron density is measured using 2D interferometry; optimisation and analysis are discussed. The Faraday rotation diagnostic, operating at 1053 nm, measures the magnetic field distribution in the plasma. Measurements obtained simultaneously by these diagnosticsmore » are used to constrain analysis, increasing the accuracy of interpretation.« less

  8. FDVIBSPC16: Sheath Flow SERS for Chemical Profiling in Urine

    PubMed Central

    Riordan, Colleen M.; Jacobs, Kevin T.; Negri, Pierre; Schultz, Zachary D.

    2016-01-01

    The molecular specificity and sensitivity of surface enhanced Raman scattering (SERS) makes it an attractive method for biomedical diagnostics. Here we present results demonstrating the utility and complications for SERS characterization in urine. The chemical fingerprint characteristic of Raman spectra suggests use as a label free diagnostic; however, the complex composition of biological fluids presents a tremendous challenge. In particular, the limited number of surface sites and competing absorption tend to mask the presence of analytes in solution, particularly when the solution contains multiple analytes. To address these problems and characterize biological fluids we have demonstrated a sheath-flow interface for SERS detection. This sheath-flow SERS interface uses hydrodynamic focusing to confine analyte molecules eluting out of a column onto a planar SERS substrate where the molecules are detected by their intrinsic SERS signal. In this report we compare direct detection of benzoylecgonine in urine using DSERS with chemical profiling by capillary zone electrophoresis and sheath-flow SERS detection. The SERS spectrum from the observed migration peaks can identify benzoylecgonine and other distinct spectra are also observed, suggesting improved chemical diagnostics in urine. With over 2000 reported compounds in urine, identification of each of the detected species is an enormous task. Nonetheless, these samples provide a benchmark to establish the potential clinical utility of sheath-flow SERS detection. PMID:27034996

  9. In-situ diagnostic tools for hydrogen transfer leak characterization in PEM fuel cell stacks part II: Operational applications

    NASA Astrophysics Data System (ADS)

    Niroumand, Amir M.; Homayouni, Hooman; DeVaal, Jake; Golnaraghi, Farid; Kjeang, Erik

    2016-08-01

    This paper describes a diagnostic tool for in-situ characterization of the rate and distribution of hydrogen transfer leaks in Polymer Electrolyte Membrane (PEM) fuel cell stacks. The method is based on reducing the air flow rate from a high to low value at a fixed current, while maintaining an anode overpressure. At high air flow rates, the reduction in air flow results in lower oxygen concentration in the cathode and therefore reduction in cell voltages. Once the air flow rate in each cell reaches a low value at which the cell oxygen-starves, the voltage of the corresponding cell drops to zero. However, oxygen starvation results from two processes: 1) the electrochemical oxygen reduction reaction which produces current; and 2) the chemical reaction between oxygen and the crossed over hydrogen. In this work, a diagnostic technique has been developed that accounts for the effect of the electrochemical reaction on cell voltage to identify the hydrogen leak rate and number of leaky cells in a fuel cell stack. This technique is suitable for leak characterization during fuel cell operation, as it only requires stack air flow and voltage measurements, which are readily available in an operational fuel cell system.

  10. Recent Developments in X-Ray Diagnostics for Cryogenic and Optically Dense Coaxial Rocket Sprays

    NASA Technical Reports Server (NTRS)

    Radke, Christopher D.; Kastengren, Alan L.; Meyer, Terrence R.

    2017-01-01

    The mixing and atomization of propellants is often characterized by optically dense flow fields and complex breakup dynamics. In the development of propulsion systems, the complexity of relevant physics and the range of spatio-temporal scales often makes computational simulation impractical for full scale injector elements; consequently, continued research into improved systems for experimental flow diagnostics is ongoing. One area of non-invasive flow diagnostics which has seen widespread growth is using synchrotron based x-ray diagostics. Over the past 3 years, a series of water and cryogenic based experiments were performed at the Advanced Photon Source, Argonne National Lab, on a NASA in-house designed swirl co-axial rocket injector, designed for operation using liquid oxygen and liquid methane in support of Project Morpheus. A range of techniques, such as x-ray fluorescence and time-averaged radiography were performed providing qualitative and quantitative mass and phase distributions, and were complemented by investigations using time-resolved radiography and white beam imaging, which provided information on breakup and mixing dynamics. Results of these investigations are presented, and conclusions regarding the viability of x-ray based diagnostics are discussed.

  11. Development of an EMC3-EIRENE Synthetic Imaging Diagnostic

    NASA Astrophysics Data System (ADS)

    Meyer, William; Allen, Steve; Samuell, Cameron; Lore, Jeremy

    2017-10-01

    2D and 3D flow measurements are critical for validating numerical codes such as EMC3-EIRENE. Toroidal symmetry assumptions preclude tomographic reconstruction of 3D flows from single camera views. In addition, the resolution of the grids utilized in numerical code models can easily surpass the resolution of physical camera diagnostic geometries. For these reasons we have developed a Synthetic Imaging Diagnostic capability for forward projection comparisons of EMC3-EIRENE model solutions with the line integrated images from the Doppler Coherence Imaging diagnostic on DIII-D. The forward projection matrix is 2.8 Mpixel by 6.4 Mcells for the non-axisymmetric case we present. For flow comparisons, both simple line integral, and field aligned component matrices must be calculated. The calculation of these matrices is a massive embarrassingly parallel problem and performed with a custom dispatcher that allows processing platforms to join mid-problem as they become available, or drop out if resources are needed for higher priority tasks. The matrices are handled using standard sparse matrix techniques. Prepared by LLNL under Contract DE-AC52-07NA27344. This material is based upon work supported by the U.S. DOE, Office of Science, Office of Fusion Energy Sciences. LLNL-ABS-734800.

  12. Malaria and other febrile diseases among travellers: the experience of a reference centre located outside the Brazilian Amazon Region.

    PubMed

    Dotrário, Andréa Beltrami; Menon, Lucas José Bazzo; Bollela, Valdes Roberto; Martinez, Roberto; de Almeida E Araújo, Daniel Cardoso; da Fonseca, Benedito Antônio Lopes; Santana, Rodrigo de C

    2016-05-26

    Malaria is endemic in countries located in tropical and sub-tropical regions. The increasing flow of domestic and international travellers has made malaria a relevant health problem even in non-endemic regions. Malaria has been described as the main diagnosis among travellers presenting febrile diseases after returning from tropical countries. In Brazil, malaria transmission occurs mainly in the Amazon region. Outside this area, malaria transmission is of low magnitude. This cross-sectional study aimed to describe the experience in the diagnosis of malaria in a reference centre located outside the Brazilian Amazon Region, emphasizing the differences in clinical and laboratory markers between cases of malaria and those of other febrile diseases (OFD). Medical charts from adult patients (≥18 years) who underwent a thick smear test (TST) for malaria, between January 2001 and December 2014, were retrospectively reviewed. A total of 458 cases referred to perform the TST were included. Malaria was diagnosed in 193 (42 %) episodes. The remaining 265 episodes (58 %) were grouped as OFD. The majority of malaria episodes were acquired in the Brazilian Amazon Region. The median time between the onset of symptoms and the TST was 7 days. Only 53 (11.5 %) episodes were tested within the first 48 h after symptom onset. Comparing malaria with OFD, jaundice, nausea, vomiting, and reports of fever were more prevalent in the malaria group. Low platelet count and elevated bilirubin levels were also related to the diagnosis of malaria. The results indicate that outside the endemic area travellers presenting febrile disease suspected of being malaria underwent diagnostic test after considerable delay. The reporting of fever combined with a recent visit to an endemic area should promptly evoke the hypothesis of malaria. In these cases, specific diagnostic tests for malaria should be a priority. For cases that jump this step, the presence of elevated bilirubin or thrombocytopaenia should also indicate a diagnosis of malaria.

  13. Vitrectomy for the diagnosis and management of uveitis of unknown cause.

    PubMed

    Margolis, Ron; Brasil, Oswaldo F M; Lowder, Careen Y; Singh, Rishi P; Kaiser, Peter K; Smith, Scott D; Perez, Victor L; Sonnie, Christine; Sears, Jonathan E

    2007-10-01

    To determine the diagnostic yield of tests commonly used for vitreous fluid analysis in eyes with suspected intraocular infection or malignancy. Noncomparative interventional case series. Forty-four consecutive patients (45 eyes) treated from 1998 through 2006 with posterior segment inflammation who underwent pars plana vitrectomy for diagnostic purposes. Vitreous specimens obtained via pars plana vitrectomy were analyzed by microbiologic culture, cytologic analysis, and flow cytometry. Diagnostic yield and sensitivity of each test performed on vitreous specimens and visual outcomes of eyes that underwent diagnostic vitrectomy (DVx). Preoperative diagnoses were infection in 15 eyes and malignancy in 30 eyes. Overall, vitreous analysis identified a specific cause in 9 (20%) of 45 eyes. The overall sensitivity of DVx was 63.6%. The sensitivities of individual tests were: culture, 50%; cytologic analysis, 66.7%; and flow cytometry, 83.3%. The yields of diagnostic tests were: culture, 5.7%; cytologic analysis, 14.3%; and flow cytometry, 20.6%. Final diagnoses were infection in 6 eyes, malignancy in 9 eyes, and idiopathic in 30 eyes. Mean visual acuity improved significantly in the first 6 months after DVx. Visual acuity improved in 60% of eyes, with 37.8% of eyes improving by 3 lines or more. Analysis of vitreous fluid by widely available tests is useful in identifying intraocular infection or malignancy. Most patients experienced a substantial improvement in vision.

  14. Accuracy of Referring Provider and Endoscopist Impressions of Colonoscopy Indication.

    PubMed

    Naveed, Mariam; Clary, Meredith; Ahn, Chul; Kubiliun, Nisa; Agrawal, Deepak; Cryer, Byron; Murphy, Caitlin; Singal, Amit G

    2017-07-01

    Background: Referring provider and endoscopist impressions of colonoscopy indication are used for clinical care, reimbursement, and quality reporting decisions; however, the accuracy of these impressions is unknown. This study assessed the sensitivity, specificity, positive and negative predictive value, and overall accuracy of methods to classify colonoscopy indication, including referring provider impression, endoscopist impression, and administrative algorithm compared with gold standard chart review. Methods: We randomly sampled 400 patients undergoing a colonoscopy at a Veterans Affairs health system between January 2010 and December 2010. Referring provider and endoscopist impressions of colonoscopy indication were compared with gold-standard chart review. Indications were classified into 4 mutually exclusive categories: diagnostic, surveillance, high-risk screening, or average-risk screening. Results: Of 400 colonoscopies, 26% were performed for average-risk screening, 7% for high-risk screening, 26% for surveillance, and 41% for diagnostic indications. Accuracy of referring provider and endoscopist impressions of colonoscopy indication were 87% and 84%, respectively, which were significantly higher than that of the administrative algorithm (45%; P <.001 for both). There was substantial agreement between endoscopist and referring provider impressions (κ=0.76). All 3 methods showed high sensitivity (>90%) for determining screening (vs nonscreening) indication, but specificity of the administrative algorithm was lower (40.3%) compared with referring provider (93.7%) and endoscopist (84.0%) impressions. Accuracy of endoscopist, but not referring provider, impression was lower in patients with a family history of colon cancer than in those without (65% vs 84%; P =.001). Conclusions: Referring provider and endoscopist impressions of colonoscopy indication are both accurate and may be useful data to incorporate into algorithms classifying colonoscopy indication. Copyright © 2017 by the National Comprehensive Cancer Network.

  15. Cochineal dye-induced immediate allergy: Review of Japanese cases and proposed new diagnostic chart.

    PubMed

    Takeo, Naoko; Nakamura, Masashi; Nakayama, Satoshi; Okamoto, Osamu; Sugimoto, Naoki; Sugiura, Shinichi; Sato, Nayu; Harada, Susumu; Yamaguchi, Masao; Mitsui, Naoya; Kubota, Yumiko; Suzuki, Kayoko; Terada, Makoto; Nagai, Akiyo; Sowa-Osako, Junko; Hatano, Yutaka; Akiyama, Hiroshi; Yagami, Akiko; Fujiwara, Sakuhei; Matsunaga, Kayoko

    2018-04-25

    Cochineal dye is used worldwide as a red coloring in foods, drinks, cosmetics, quasi-drugs, and drugs. The main component of the red color is carminic acid (CA). Carmine is an aluminum- or calcium-chelated product of CA. CA and carmine usually contain contaminating proteins, including a 38-kDa protein thought to be the primary allergen. Severe allergic reactions manifest as anaphylaxis. The aim of this study was to review all Japanese reported cases and propose useful diagnostic chart. All reported Japanese cases of cochineal dye-induced immediate allergy were reviewed, and newly registered cases were examined by skin prick test (SPT) with cochineal extract (CE) and measurement of CE and carmine-specific serum IgE test. Two-dimensional (2D) western blotting using patient serum was conducted to identify the antigen. Twenty-two Japanese cases have been reported. SPT and the level of specific IgE test indicated that six cases should be newly registered as cochineal dye allergy. All cases were adult females, and all cases except three involved anaphylaxis; 13 cases involved past history of local symptoms associated with cosmetics use. Japanese strawberry juice and fish-meat sausage, and European processed foods (especially macarons made in France) and drinks were recent major sources of allergen. 2D western blotting showed that patient IgE reacted to the 38-kDa protein and other proteins. Serum from healthy controls also weakly reacted with these proteins. SPT with CE and determination of the level of CE and carmine-specific IgE test are useful methods for the diagnosis of cochineal dye allergy. Copyright © 2018 Japanese Society of Allergology. Production and hosting by Elsevier B.V. All rights reserved.

  16. Laser Light Scattering Diagnostic for Measurement of Flow Velocity in Vicinity of Propagating Shock Waves

    NASA Technical Reports Server (NTRS)

    Seasholtz, Richard G.; Buggele, Alvin E.

    2002-01-01

    A laser light scattering diagnostic for measurement of dynamic flow velocity at a point is described. The instrument is being developed for use in the study of propagating shock waves and detonation waves in pulse detonation engines under development at the NASA Glenn Research Center (GRC). The approach uses a Fabry-Perot interferometer to measure the Doppler shift of laser light scattered from small (submicron) particles in the flow. The high-speed detection system required to resolve the transient response as a shock wave crosses the probe volume uses fast response photodetectors, and a PC based data acquisition system. Preliminary results of measurements made in the GRC Mach 4, 10 by 25 cm supersonic wind tunnel are presented. Spontaneous condensation of water vapor in the flow is used as seed. The tunnel is supplied with continuous air flow at up to 45 psia and the flow is exhausted into the GRC laboratory-wide altitude exhaust system at pressures down to 0.3 psia.

  17. Space Laboratory on a Table Top: A Next Generative ECLSS design and diagnostic tool

    NASA Technical Reports Server (NTRS)

    Ramachandran, N.

    2005-01-01

    This paper describes the development plan for a comprehensive research and diagnostic tool for aspects of advanced life support systems in space-based laboratories. Specifically it aims to build a high fidelity tabletop model that can be used for the purpose of risk mitigation, failure mode analysis, contamination tracking, and testing reliability. We envision a comprehensive approach involving experimental work coupled with numerical simulation to develop this diagnostic tool. It envisions a 10% scale transparent model of a space platform such as the International Space Station that operates with water or a specific matched index of refraction liquid as the working fluid. This allows the scaling of a 10 ft x 10 ft x 10 ft room with air flow to 1 ft x 1 ft x 1 ft tabletop model with water/liquid flow. Dynamic similitude for this length scale dictates model velocities to be 67% of full-scale and thereby the time scale of the model to represent 15% of the full- scale system; meaning identical processes in the model are completed in 15% of the full- scale-time. The use of an index matching fluid (fluid that matches the refractive index of cast acrylic, the model material) allows making the entire model (with complex internal geometry) transparent and hence conducive to non-intrusive optical diagnostics. So using such a system one can test environment control parameters such as core flows (axial flows), cross flows (from registers and diffusers), potential problem areas such as flow short circuits, inadequate oxygen content, build up of other gases beyond desirable levels, test mixing processes within the system at local nodes or compartments and assess the overall system performance. The system allows quantitative measurements of contaminants introduced in the system and allows testing and optimizing the tracking process and removal of contaminants. The envisaged system will be modular and hence flexible for quick configuration change and subsequent testing. The data and inferences from the tests will allow for improvements in the development and design of next generation life support systems and configurations. Preliminary experimental and modeling work in this area will be presented. This involves testing of a single inlet-exit model with detailed 3-D flow visualization and quantitative diagnostics and computational modeling of the system.

  18. Malpractice and medical liability. European Guidelines on Methods of Ascertainment and Criteria of Evaluation.

    PubMed

    Ferrara, Santo Davide; Baccino, Eric; Bajanowski, Thomas; Boscolo-Berto, Rafael; Castellano, Maria; De Angel, Ricardo; Pauliukevičius, Alvydas; Ricci, Pietrantonio; Vanezis, Peter; Vieira, Duarte Nuno; Viel, Guido; Villanueva, Enrique

    2013-05-01

    The manuscript presents the European Guidelines on medico-legal Methods of Ascertainment and Criteria of Evaluation in cases of suspected subjective "Medical Responsibility and/or Liability" developed by an international working group under the patronage of the European Academy of Legal Medicine. It includes a step-by-step illustrated explanation of approved Flow Charts, articulated in 18 sequential steps and comprehensive of both Methods of Ascertainment and Evaluation Criteria.

  19. Numerical and Experimental Investigation of Confined Turbulent Multiple Transverse Jets (Briefing Charts)

    DTIC Science & Technology

    2014-07-29

    14.3. The momentum and scalar mixing is investigated through the solution of the Reynolds-Averaged Navier Stokes (RANS) equations. The mean scalar...demonstrated symmetry , only a one-half section of the geometry is considered. All numerical simulations capture salient flow structures such as the counter...distribution unlimited Symmetry Plane Walls Diluents’ Inlet Vy = 100 m/s Previous Numerical Work at AFRL: Air-to-Air Experimental Configuration

  20. Simulators' validation study: Problem solution logic

    NASA Technical Reports Server (NTRS)

    Schoultz, M. B.

    1974-01-01

    A study was conducted to validate the ground based simulators used for aircraft environment in ride-quality research. The logic to the approach for solving this problem is developed. The overall problem solution flow chart is presented. The factors which could influence the human response to the environment on board the aircraft are analyzed. The mathematical models used in the study are explained. The steps which were followed in conducting the validation tests are outlined.

  1. Detailed description of the HP-9825A HFRMP trajectory processor (TRAJ)

    NASA Technical Reports Server (NTRS)

    Kindall, S. M.; Wilson, S. W.

    1979-01-01

    The computer code for the trajectory processor of the HP-9825A High Fidelity Relative Motion Program is described in detail. The processor is a 12-degrees-of-freedom trajectory integrator which can be used to generate digital and graphical data describing the relative motion of the Space Shuttle Orbiter and a free-flying cylindrical payload. Coding standards and flow charts are given and the computational logic is discussed.

  2. Spectrum Efficiency Through Dynamic Spectrum Access Techniques (Briefing Charts)

    DTIC Science & Technology

    2014-06-01

    Telemetry Data Sources IP BASED TELEMETRY STATION Flow control • Volume- based • Credit- based • Rate- based Signaling using custom protocols or standards...Responsible for all T&E infrastructure assessment within the Major Range and Test Facility Base (MRTFB) DoD Directive 3200.11 • Administer three...Memorandum Unleashing of the Wireless Broadband Revolution THE WHY: Based on the view that “we are now beginning the next transformation in

  3. Orion Launch Abort Vehicle Separation Analysis Using OVERFLOW

    NASA Technical Reports Server (NTRS)

    Booth, Tom

    2010-01-01

    This slide presentation reviews the use of OVERFLOW, a flow solver, to analyze the effect of separation for a launch abort vehicle (i.e., Orion capsule) if required. Included in the presentation are views of the geometry, and the Overset grids, listing of the assumptions, the general run strategy, inputs into the Overflow solver, the required computational resources, the results of the convergence study. Charts and graphics are presented to show the results.

  4. User's manual for three-dimensional analysis of propeller flow fields

    NASA Technical Reports Server (NTRS)

    Chaussee, D. S.; Kutler, P.

    1983-01-01

    A detailed operating manual is presented for the prop-fan computer code (in addition to supporting programs) recently developed by Kutler, Chaussee, Sorenson, and Pulliam while at the NASA'S Ames Research Center. This code solves the inviscid Euler equations using an implicit numerical procedure developed by Beam and Warming of Ames. A description of the underlying theory, numerical techniques, and boundary conditions with equations, formulas, and methods for the mesh generation program (MGP), three dimensional prop-fan flow field program (3DPFP), and data reduction program (DRP) is provided, together with complete operating instructions. In addition, a programmer's manual is also provided to assist the user interested in modifying the codes. Included in the programmer's manual for each program is a description of the input and output variables, flow charts, program listings, sample input and output data, and operating hints.

  5. Shear flow control of cold and heated rectangular jets by mechanical tabs. Volume 2: Tabulated data

    NASA Technical Reports Server (NTRS)

    Brown, W. H.; Ahuja, K. K.

    1989-01-01

    The effects of mechanical protrusions on the jet mixing characteristics of rectangular nozzles for heated and unheated subsonic and supersonic jet plumes were studied. The characteristics of a rectangular nozzle of aspect ratio 4 without the mechanical protrusions were first investigated. Intrusive probes were used to make the flow measurements. Possible errors introduced by intrusive probes in making shear flow measurements were also examined. Several scaled sizes of mechanical tabs were then tested, configured around the perimeter of the rectangular jet. Both the number and the location of the tabs were varied. From this, the best configuration was selected. This volume contains tabulated data for each of the data runs cited in Volume 1. Baseline characteristics, mixing modifications (subsonic and supersonic, heated and unheated) and miscellaneous charts are included.

  6. Three-phase bone scintigraphy for diagnosis of Charcot neuropathic osteoarthropathy in the diabetic foot - does quantitative data improve diagnostic value?

    PubMed

    Fosbøl, M; Reving, S; Petersen, E H; Rossing, P; Lajer, M; Zerahn, B

    2017-01-01

    To investigate whether inclusion of quantitative data on blood flow distribution compared with visual qualitative evaluation improve the reliability and diagnostic performance of 99 m Tc-hydroxymethylene diphosphate three-phase bone scintigraphy (TPBS) in patients suspected for charcot neuropathic osteoarthropathy (CNO) of the foot. A retrospective cohort study of TPBS performed on 148 patients with suspected acute CNO referred from a single specialized diabetes care centre. The quantitative blood flow distribution was calculated based on the method described by Deutsch et al. All scintigraphies were re-evaluated by independent, blinded observers twice with and without quantitative data on blood flow distribution at ankle and focus level, respectively. The diagnostic validity of TPBS was determined by subsequent review of clinical data and radiological examinations. A total of 90 patients (61%) had confirmed diagnosis of CNO. The sensitivity, specificity and accuracy of three-phase bone scintigraphy without/with quantitative data were 89%/88%, 58%/62% and 77%/78%, respectively. The intra-observer agreement improved significantly by adding quantitative data in the evaluation (Kappa value 0·79/0·94). The interobserver agreement was not significantly improved. Adding quantitative data on blood flow distribution in the interpretation of TBPS improves intra-observer variation, whereas no difference in interobserver variation was observed. The sensitivity of TPBS in the diagnosis of CNO is high, but holds limited specificity. Diagnostic performance does not improve using quantitative data in the evaluation. This may be due to the reference intervals applied in the study or the absence of a proper gold standard diagnostic procedure for comparison. © 2015 Scandinavian Society of Clinical Physiology and Nuclear Medicine. Published by John Wiley & Sons Ltd.

  7. Added diagnostic value of magnetoencephalography (MEG) in patients suspected for epilepsy, where previous, extensive EEG workup was unrevealing.

    PubMed

    Duez, Lene; Beniczky, Sándor; Tankisi, Hatice; Hansen, Peter Orm; Sidenius, Per; Sabers, Anne; Fuglsang-Frederiksen, Anders

    2016-10-01

    To elucidate the possible additional diagnostic yield of MEG in the workup of patients with suspected epilepsy, where repeated EEGs, including sleep-recordings failed to identify abnormalities. Fifty-two consecutive patients with clinical suspicion of epilepsy and at least three normal EEGs, including sleep-EEG, were prospectively analyzed. The reference standard was inferred from the diagnosis obtained from the medical charts, after at least one-year follow-up. MEG (306-channel, whole-head) and simultaneous EEG (MEG-EEG) was recorded for one hour. The added sensitivity of MEG was calculated from the cases where abnormalities were seen in MEG but not EEG. Twenty-two patients had the diagnosis epilepsy according to the reference standard. MEG-EEG detected abnormalities, and supported the diagnosis in nine of the 22 patients with the diagnosis epilepsy at one-year follow-up. Sensitivity of MEG-EEG was 41%. The added sensitivity of MEG was 18%. MEG-EEG was normal in 28 of the 30 patients categorized as 'not epilepsy' at one year follow-up, yielding a specificity of 93%. MEG provides additional diagnostic information in patients suspected for epilepsy, where repeated EEG recordings fail to demonstrate abnormality. MEG should be included in the diagnostic workup of patients where the conventional, widely available methods are unrevealing. Copyright © 2016 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights reserved.

  8. Recognition of psychiatric disorders in musculoskeletal and cardiovascular rehabilitation patients.

    PubMed

    Härter, Martin; Woll, Sonja; Reuter, Katrin; Wunsch, Alexandra; Bengel, Jürgen

    2004-07-01

    To investigate the detection rate of psychiatric disorders in rehabilitation inpatients with musculoskeletal and cardiovascular diseases (CVDs). Cross-sectional survey; analysis of medical charts and discharge reports, combined with standardized diagnostic interviews. Four orthopedic and 6 cardiovascular rehabilitation hospitals in southwest Germany. More than 1700 inpatients with different musculoskeletal disorders and CVDs participated in the survey. On the basis of their General Health Questionnaire score, 205 patients with musculoskeletal diseases and 164 patients with CVDs were selected randomly for standardized interviews. Discharge reports of interviewed patients were analyzed. Not applicable. Clinical interview (Composite International Diagnostic Interview [CIDI]) to obtain diagnoses of psychiatric disorders as defined by the Diagnostic and Statistical Manual of Mental Disorders, 4th edition (DSM-IV). Assessment of psychosocial burden and diagnoses of mental disorders, as well as admission to psychologic treatments, based on discharge reports of the attending physicians. The detection rate (sensitivity) of mental disorders was 48% in the orthopedic rehabilitation patients and 32% in the cardiovascular patients. Specificity was 80% in musculoskeletal patients and 87% in cardiovascular patients. Differential diagnostic competencies were lacking, and only half of the physicians' diagnoses corresponded to the CIDI diagnoses. The results showed a need for current DSM-IV or International Classification of Diseases, 10th edition, psychodiagnostics in medical rehabilitation to detect mental disorders in patients in the rehabilitation process at an earlier stage and to refer patients with comorbid mental disorders to adequate treatment.

  9. The NASA Langley Research Center 0.3-meter transonic cryogenic tunnel T-P/Re-M controller manual

    NASA Technical Reports Server (NTRS)

    Balakrishna, S.; Kilgore, W. Allen

    1989-01-01

    A new microcomputer based controller for the 0.3-m Transonic Cryogenic Tunnel (TCT) has been commissioned in 1988 and has reliably operated for more than a year. The tunnel stagnation pressure, gas stagnation temperature, tunnel wall structural temperature and flow Mach number are precisely controlled by the new controller in a stable manner. The tunnel control hardware, software, and the flow chart to assist in calibration of the sensors, actuators, and the controller real time functions are described. The software installation details are also presented. The report serves as the maintenance and trouble shooting manual for the 0.3-m TCT controller.

  10. Theory of low frequency noise transmission through turbines

    NASA Technical Reports Server (NTRS)

    Matta, R. K.; Mani, R.

    1979-01-01

    Improvements of the existing theory of low frequency noise transmission through turbines and development of a working prediction tool are described. The existing actuator-disk model and a new finite-chord model were utilized in an analytical study. The interactive effect of adjacent blade rows, higher order spinning modes, blade-passage shocks, and duct area variations were considered separately. The improved theory was validated using the data acquired in an earlier NASA program. Computer programs incorporating the improved theory were produced for transmission loss prediction purposes. The programs were exercised parametrically and charts constructed to define approximately the low frequency noise transfer through turbines. The loss through the exhaust nozzle and flow(s) was also considered.

  11. Bringing explicit insight into cognitive psychology features during clinical reasoning seminars: a prospective, controlled study.

    PubMed

    Nendaz, Mathieu R; Gut, Anne M; Louis-Simonet, Martine; Perrier, Arnaud; Vu, Nu V

    2011-04-01

    Facets of reasoning competence influenced by an explicit insight into cognitive psychology features during clinical reasoning seminars have not been specifically explored. This prospective, controlled study, conducted at the University of Geneva Faculty of Medicine, Switzerland, assessed the impact on sixth-year medical students' patient work-up of case-based reasoning seminars, bringing them explicit insight into cognitive aspects of their reasoning. Volunteer students registered for our three-month Internal Medicine elective were assigned to one of two training conditions: standard (control) or modified (intervention) case-based reasoning seminars. These seminars start with the patient's presenting complaint and the students must ask the tutor for additional clinical information to progress through case resolution. For this intervention, the tutors made each step explicit to students and encouraged self-reflection on their reasoning processes. At the end of their elective, students' performances were assessed through encounters with two standardized patients and chart write-ups. Twenty-nine students participated, providing a total of 58 encounters. The overall differences in accuracy of the final diagnosis given to the patient at the end of the encounter (control 63% vs intervention 74%, p = 0.53) and of the final diagnosis mentioned in the patient chart (61% vs 70%, p = 0.58) were not statistically significant. The students in the intervention group significantly more often listed the correct diagnosis among the differential diagnoses in their charts (75% vs 97%, p = 0.02). This case-based clinical reasoning seminar intervention, designed to bring students insight into cognitive features of their reasoning, improved aspects of diagnostic competence.

  12. Characteristics of patients with spondyloarthritis followed in rheumatology units in Spain. emAR II study.

    PubMed

    Casals-Sánchez, José Luis; García De Yébenes Prous, María Jesús; Descalzo Gallego, Miguel Ángel; Barrio Olmos, Juan Manuel; Carmona Ortells, Loreto; Hernández García, Cesar

    2012-01-01

    To describe the main demographic and clinical features of patients with spondyloarthropaties in Spain. Review of randomized clinical charts of patients with spondyloarthropaties with at least one visit to the rheumatologist in the previous two years. Information was collected on demographic and clinical data (duration of illness, diagnostic category, disease activity, extrarticular manifestations, comorbidity and work disability). 1,168 patients were included in the study. Their median age was 49.2 years (39.7-60.5), 68.0% were males, and median time of disease was 105.1 month (48.4-192.5). The diagnoses and clinical data such as the BASDAI were reported only in 34,0% of the patients. The most widely used measure of metrology, the Schober test, was missing in 37.7% of the clinical charts. The patients included had the following diagnoses: Ankylosing spondylitis (n = 629, 55.2%), Psoriatic arthritis (n= 253, 22.2%), Undifferentiated spondyloarthritis (n = 184, 16.1%), Arthritis associated to Inflammatory bowel disease (n= 50, 4.4%), and Reactive arthritis (n= 16, 1.4%). The most common extraarticular manifestations were psoriasis (20.8%), anterior uveitis (19.4%), and enthesitis (16.9%). Some kind of work disability was reported in 8.3% of the patients. Demographic and clinical characteristics of patients with spondyloarthropaties in Spain do not differ as a whole from other published studies, except for Undifferentiated Spondyloarthritis, which was more likely in our patients than in other studies. The quality of the records of activity in the clinical charts could be improved. Copyright © 2011 Elsevier España, S.L. All rights reserved.

  13. Validation of International Classification of Diseases coding for bone metastases in electronic health records using technology-enabled abstraction.

    PubMed

    Liede, Alexander; Hernandez, Rohini K; Roth, Maayan; Calkins, Geoffrey; Larrabee, Katherine; Nicacio, Leo

    2015-01-01

    The accuracy of bone metastases diagnostic coding based on International Classification of Diseases, ninth revision (ICD-9) is unknown for most large databases used for epidemiologic research in the US. Electronic health records (EHR) are the preferred source of data, but often clinically relevant data occur only as unstructured free text. We examined the validity of bone metastases ICD-9 coding in structured EHR and administrative claims relative to the complete (structured and unstructured) patient chart obtained through technology-enabled chart abstraction. Female patients with breast cancer with ≥1 visit after November 2010 were identified from three community oncology practices in the US. We calculated sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of bone metastases ICD-9 code 198.5. The technology-enabled abstraction displays portions of the chart to clinically trained abstractors for targeted review, thereby maximizing efficiency. We evaluated effects of misclassification of patients developing skeletal complications or treated with bone-targeting agents (BTAs), and timing of BTA. Among 8,796 patients with breast cancer, 524 had confirmed bone metastases using chart abstraction. Sensitivity was 0.67 (95% confidence interval [CI] =0.63-0.71) based on structured EHR, and specificity was high at 0.98 (95% CI =0.98-0.99) with corresponding PPV of 0.71 (95% CI =0.67-0.75) and NPV of 0.98 (95% CI =0.98-0.98). From claims, sensitivity was 0.78 (95% CI =0.74-0.81), and specificity was 0.98 (95% CI =0.98-0.98) with PPV of 0.72 (95% CI =0.68-0.76) and NPV of 0.99 (95% CI =0.98-0.99). Structured data and claims missed 17% of bone metastases (89 of 524). False negatives were associated with measurable overestimation of the proportion treated with BTA or with a skeletal complication. Median date of diagnosis was delayed in structured data (32 days) and claims (43 days) compared with technology-assisted EHR. Technology-enabled chart abstraction of unstructured EHR greatly improves data quality, minimizing false negatives when identifying patients with bone metastases that may lead to inaccurate conclusions that can affect delivery of care.

  14. 21 CFR 870.1240 - Flow-directed catheter.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 8 2011-04-01 2011-04-01 false Flow-directed catheter. 870.1240 Section 870.1240 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES CARDIOVASCULAR DEVICES Cardiovascular Diagnostic Devices § 870.1240 Flow-directed catheter...

  15. 21 CFR 870.1240 - Flow-directed catheter.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Flow-directed catheter. 870.1240 Section 870.1240 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES CARDIOVASCULAR DEVICES Cardiovascular Diagnostic Devices § 870.1240 Flow-directed catheter...

  16. Nanostructured tracers for laser-based diagnostics in high-speed flows

    NASA Astrophysics Data System (ADS)

    Ghaemi, S.; Schmidt-Ott, A.; Scarano, F.

    2010-10-01

    The potential application of aggregates of nanoparticles for high-speed flow diagnostics is investigated. Aluminum nanoparticles around 10 nm in diameter are produced by spark discharge in argon gas. Through rapid coagulation and oxidation, aggregates of small effective density are formed. They are characterized by microscopy and their aerodynamics and optical properties are theoretically evaluated. The performance of the aggregates is experimentally investigated across an oblique shock wave in a supersonic wind tunnel of 3 × 3 cm2 cross-section at Mach 2. Particle image velocimetry is used to quantify the time response of the aggregates. The investigations are also carried out on compact titanium agglomerates to provide a base for comparison. The results yield a relaxation time of 0.27 µs for the nanostructured aluminum aggregates, which is an order of magnitude reduction with respect to the compact titanium nanoparticles. This work demonstrates the applicability of nanostructured aggregates for laser-based diagnostics in supersonic and hypersonic flows.

  17. Rayleigh Scattering Diagnostic for Simultaneous Measurements of Dynamic Density and Velocity

    NASA Technical Reports Server (NTRS)

    Seasholtz, Richard G.; Panda, J.

    2000-01-01

    A flow diagnostic technique based on the molecular Rayleigh scattering of laser light is used to obtain dynamic density and velocity data in turbulent flows. The technique is based on analyzing the Rayleigh scattered light with a Fabry-Perot interferometer and recording information about the interference pattern with a multiple anode photomultiplier tube (PMT). An artificial neural network is used to process the signals from the PMT to recover the velocity time history, which is then used to calculate the velocity power spectrum. The technique is illustrated using simulated data. The results of an experiment to measure the velocity power spectrum in a low speed (100 rn/sec) flow are also presented.

  18. Virtual reality aided visualization of fluid flow simulations with application in medical education and diagnostics.

    PubMed

    Djukic, Tijana; Mandic, Vesna; Filipovic, Nenad

    2013-12-01

    Medical education, training and preoperative diagnostics can be drastically improved with advanced technologies, such as virtual reality. The method proposed in this paper enables medical doctors and students to visualize and manipulate three-dimensional models created from CT or MRI scans, and also to analyze the results of fluid flow simulations. Simulation of fluid flow using the finite element method is performed, in order to compute the shear stress on the artery walls. The simulation of motion through the artery is also enabled. The virtual reality system proposed here could shorten the length of training programs and make the education process more effective. © 2013 Published by Elsevier Ltd.

  19. Numerical Investigation of a Novel Microscale Swirling Jet Reactor for Medical Sensor Applications

    NASA Astrophysics Data System (ADS)

    Ogus, G.; Baelmans, M.; Lammertyn, J.; Vanierschot, M.

    2018-03-01

    A microscale swirler and corresponding reactor for a recent detection and analysis tool for healthcare applications, Fiber optic-surface plasmon resonance (FO-SPR), is presented in this study. The sensor is a 400 μm diameter needle that works as a detector for certain particles. Currently, the detection process relies on diffusion of particles towards the sensor and hence diagnostic time is rather long. The aim of this study is to decrease that diagnostic time by introducing convective mixing in the reactor by means of a swirling inlet flow. This will increase the particle deposition on the FO-SPR sensor and hence an increase in detection rate, as this rate strongly depends on the aimed particle concentration near the sensor. As the flow rates are rather low and the length scales are small, the flow in such reactors is laminar. In this study, robustly controllable mixing features of a swirling jet flow is used to increase the particle concentration near the sensor. A numerical analysis (CFD) is performed to characterize the flow and a detailed analysis of flow structures depending on the flow rate are reported.

  20. Presentation of a quality management program in off-pump coronary bypass surgery.

    PubMed

    Bougioukakis, Petros; Kluegl, Stefan J; Babin-Ebell, Joerg; Tagarakis, Giorgios I; Mandewirth, Martin; Zacher, Michael; Diegeler, Anno

    2014-01-01

    To increase the number of off-pump coronary procedures at our institution, a new surgical team was formed. The first 3 years of "learning period" were accompanied by a quality management program aimed to control and adjust the surgical process and to ensure the safety and quality of the procedure. All patients were operated on by the same surgeon between January 2004 and December 2006; all procedures were performed under the following quality management protocol. First, a flow chart regulated surgical and anesthetic details. Second, an online file, named "disturbance file," was used to report work flow interruption, disturbance, and intraoperative events, that is, myocardial ischemia, hypotension, conversion to cardiopulmonary bypass, and any violation of the protocol. Each event was coded with 1 point and added to a score (the higher the score is, the greater the disturbance). Outcome parameters known as major events-major cardiac and cerebral events: mortality within 30 days/myocardial infarction confirmed by electrocardiogram or significantly high levels of total creatine kinase-myocardial muscle creatine kinase/reintervention within 30 days/stroke--and new-onset dialysis were also measured. Success was defined as freedom from any of those events and depicted in a cumulative sum control (CUSUM) chart. Outcome data and CUSUM were correlated with the intraoperative Disturbance Index. In total, 490 off-pump coronary bypass operations were performed by the named surgeon during the study period. The 30-day mortality was reduced from 4.0% to 1.9%. Disturbance Index score of greater than 1 declined from 41.6% to 23.3%. All major cardiac and cerebral events declined. The CUSUM chart showed two critical periods during the learning period, which made an adjustment of the protocol necessary. Quality management control is efficient in improving the postoperative results of a surgical procedure. A learning period is of cardinal importance for any new team wishing to engage in a novel surgical technique.

  1. Population-based prevalence of smoking in psychiatric inpatients: a focus on acute suicide risk and major diagnostic groups.

    PubMed

    Lineberry, Timothy W; Allen, Josiah D; Nash, Jessica; Galardy, Christine W

    2009-01-01

    The aim of the study was to define the extent of current and lifetime smoking by diagnostic groups and suicide risk as reason for admission in a geographically defined psychiatric inpatient cohort. The study used a population-based retrospective chart review. Smoking status and discharge diagnoses for Olmsted County, Minnesota, inpatients aged 18 to 65 admitted for psychiatric hospitalization in 2004 and 2005 were abstracted from the electronic medical record. Diagnostic groups were compared to each other using chi(2) tests and Fisher exact test to analyze smoking status within the inpatient sample with significance defined as P

  2. A cluster randomized trial evaluating the efficacy of patient navigation in improving quality of diagnostic care for patients with breast or colorectal cancer abnormalities.

    PubMed

    Wells, Kristen J; Lee, Ji-Hyun; Calcano, Ercilia R; Meade, Cathy D; Rivera, Marlene; Fulp, William J; Roetzheim, Richard G

    2012-10-01

    This study examines efficacy of a lay patient navigation (PN) program aimed to reduce time between a cancer abnormality and definitive diagnosis among racially/ethnically diverse and medically underserved populations of Tampa Bay, Florida. Using a cluster randomized design, the study consisted of 11 clinics (six navigated; five control). Patients were navigated from time of a breast or colorectal abnormality to diagnostic resolution, and to completion of cancer treatment. Using a generalized mixed-effects model to assess intervention effects, we examined: (i) length of time between abnormality and definitive diagnosis, and (ii) receipt of definitive diagnosis within the 6-month minimum follow-up period. A total of 1,267 patients participated (588 navigated; 679 control). We also included data from an additional 309 chart abstractions (139 navigated arm; 170 control arm) that assessed outcomes at baseline. PN did not have a significant effect on time to diagnostic resolution in multivariable analysis that adjusted for race-ethnicity, language, insurance status, marital status, and cancer site (P = 0.16). Although more navigated patients achieved diagnostic resolution by 180 days, results were not statistically significant (74.5% navigated vs. 68.5% control, P = 0.07). PN did not impact the overall time to completion of diagnostic care or the number of patients who reached diagnostic resolution of a cancer abnormality. Further evaluation of PN programs applied to other patient populations across the cancer continuum is necessary to gain a better perspective on its effectiveness. PN programs may not impact timely resolution of an abnormality suspicious of breast or colorectal cancer. 2012 AACR

  3. Lee-side flow over delta wings at supersonic speeds

    NASA Technical Reports Server (NTRS)

    Miller, D. S.; Wood, R. M.

    1985-01-01

    An experimental investigation of the lee-side flow on sharp leading-edge delta wings at supersonic speeds has been conducted. Pressure data were obtained at Mach numbers from 1.5 to 2.8, and three types of flow-visualization data (oil-flow, tuft, and vapor-screen) were obtained at Mach numbers from 1.7 to 2.8 for wing leading-edge sweep angles from 52.5 deg to 75 deg. From the flow-visualization data, the lee-side flows were classified into seven distinct types and a chart was developed that defines the flow mechanism as a function of the conditions normal to the wing leading edge, specifically, angle of attack and Mach number. Pressure data obtained experimentally and by a semiempirical prediction method were employed to investigate the effects of angle of attack, leading-edge sweep, and Mach number on vortex strength and vortex position. In general, the predicted and measured values of vortex-induced normal force and vortex position obtained from experimental data have the same trends with angle of attack, Mach number, and leading-edge sweep; however, the vortex-induced normal force is underpredicted by 15 to 30 percent, and the vortex spanwise location is overpredicted by approximately 15 percent.

  4. Comparison of reading speed with 3 different log-scaled reading charts.

    PubMed

    Buari, Noor Halilah; Chen, Ai-Hong; Musa, Nuraini

    2014-01-01

    A reading chart that resembles real reading conditions is important to evaluate the quality of life in terms of reading performance. The purpose of this study was to compare the reading speed of UiTM Malay related words (UiTM-Mrw) reading chart with MNread Acuity Chart and Colenbrander Reading Chart. Fifty subjects with normal sight were randomly recruited through randomized sampling in this study (mean age=22.98±1.65 years). Subjects were asked to read three different near charts aloud and as quickly as possible at random sequence. The charts were the UiTM-Mrw Reading Chart, MNread Acuity Chart and Colenbrander Reading Chart, respectively. The time taken to read each chart was recorded and any errors while reading were noted. Reading performance was quantified in terms of reading speed as words per minute (wpm). The mean reading speed for UiTM-Mrw Reading Chart, MNread Acuity Chart and Colenbrander Reading Chart was 200±30wpm, 196±28wpm and 194±31wpm, respectively. Comparison of reading speed between UiTM-Mrw Reading Chart and MNread Acuity Chart showed no significant difference (t=-0.73, p=0.72). The same happened with the reading speed between UiTM-Mrw Reading Chart and Colenbrander Reading Chart (t=-0.97, p=0.55). Bland and Altman plot showed good agreement between reading speed of UiTM-Mrw Reading Chart with MNread Acuity Chart with the Colenbrander Reading Chart. UiTM-Mrw Reading Chart in Malay language is highly comparable with standardized charts and can be used for evaluating reading speed. Copyright © 2013 Spanish General Council of Optometry. Published by Elsevier Espana. All rights reserved.

  5. Comparison of reading speed with 3 different log-scaled reading charts

    PubMed Central

    Buari, Noor Halilah; Chen, Ai-Hong; Musa, Nuraini

    2014-01-01

    Background A reading chart that resembles real reading conditions is important to evaluate the quality of life in terms of reading performance. The purpose of this study was to compare the reading speed of UiTM Malay related words (UiTM-Mrw) reading chart with MNread Acuity Chart and Colenbrander Reading Chart. Materials and methods Fifty subjects with normal sight were randomly recruited through randomized sampling in this study (mean age = 22.98 ± 1.65 years). Subjects were asked to read three different near charts aloud and as quickly as possible at random sequence. The charts were the UiTM-Mrw Reading Chart, MNread Acuity Chart and Colenbrander Reading Chart, respectively. The time taken to read each chart was recorded and any errors while reading were noted. Reading performance was quantified in terms of reading speed as words per minute (wpm). Results The mean reading speed for UiTM-Mrw Reading Chart, MNread Acuity Chart and Colenbrander Reading Chart was 200 ± 30 wpm, 196 ± 28 wpm and 194 ± 31 wpm, respectively. Comparison of reading speed between UiTM-Mrw Reading Chart and MNread Acuity Chart showed no significant difference (t = −0.73, p = 0.72). The same happened with the reading speed between UiTM-Mrw Reading Chart and Colenbrander Reading Chart (t = −0.97, p = 0.55). Bland and Altman plot showed good agreement between reading speed of UiTM-Mrw Reading Chart with MNread Acuity Chart with the Colenbrander Reading Chart. Conclusion UiTM-Mrw Reading Chart in Malay language is highly comparable with standardized charts and can be used for evaluating reading speed. PMID:25323642

  6. Regional Cerebral Blood Flow In Dementia: Receiver-Operating-Characteristic Analysis

    NASA Astrophysics Data System (ADS)

    Zemcov, Alexander; Barclay, Laurie; Sansone, Joseph; Blass, John P.; Metz, Charles E.

    1985-06-01

    The coupling of mentation to regional cerebral blood flow (rCBF) has prompted the application of the Xe-133 inhalation method of measuring rCBF in the differential diagnosis of the two most common dementing diseases, Alzheimer's disease and multi-infarct dementia (MID). In this study receiver-operating-characteristic (ROC) curve analysis was used to assess the effectiveness of a 32 detector Xe-133 inhalation system in discriminating between patients with Alzheimer's disease and normal controls, MID patients and normal controls and between patients with Alzheimer's disease and MID. The populations were clinically evaluated as 1) normal (age 63.1 + 13.1, n=23), 2) Alzheimer's disease (age 72.7 + 7.0, n=82), 3) MID (age 76.4 + 7.6, n=27): The mean flow values for all detectors were lowest for the Alzheimer's disease group, larger for the MID group and largest for the normal controls. The dynamic relationship between the correct identifications (true posi-tives) versus incorrect identifications (false positives) per detector for any 2 pairs of clinical groups varies as the cutoff value of flow is changed over the range of experimental blood flow values. Therefore a quantitative characterization of the "decision" or ROC curve (TP vs FP) for each detector and for each pair of clinical groups provides a measure of the overall diagnostic efficacy of the detector. Detectors directed approximately toward the speech, auditory and association cortices were most effective in disciminatinq between each of the dementia groups and the controls. Frontal detectors were diagnostically inefficient. The Xe-133 inhalation system provided virtually no diagnostic power in discriminating between the two forms of dementia, however. Therefore this imaging technology is most useful when assessing the general diagnostic state of dementia (Alz-heimer's disease and MID) from normal cognitive function.

  7. Fuel Spray Diagnostics

    NASA Technical Reports Server (NTRS)

    Humenik, F. M.; Bosque, M. A.

    1983-01-01

    Fundamental experimental data base for turbulent flow mixing models is provided and better prediction of the more complex turbulent chemical reacting flows. Analytical application to combustor design is provided and a better fundamental understanding of the combustion process.

  8. Progress on a Rayleigh Scattering Mass Flux Measurement Technique

    NASA Technical Reports Server (NTRS)

    Mielke-Fagan, Amy F.; Clem, Michelle M.; Elam, Kristie A.; Hirt, Stefanie M.

    2010-01-01

    A Rayleigh scattering diagnostic has been developed to provide mass flux measurements in wind tunnel flows. Spectroscopic molecular Rayleigh scattering is an established flow diagnostic tool that has the ability to provide simultaneous density and velocity measurements in gaseous flows. Rayleigh scattered light from a focused 10 Watt continuous-wave laser beam is collected and fiber-optically transmitted to a solid Fabry-Perot etalon for spectral analysis. The circular interference pattern that contains the spectral information that is needed to determine the flow properties is imaged onto a CCD detector. Baseline measurements of density and velocity in the test section of the 15 cm x 15 cm Supersonic Wind Tunnel at NASA Glenn Research Center are presented as well as velocity measurements within a supersonic combustion ramjet engine isolator model installed in the tunnel test section.

  9. Battery operated preconcentration-assisted lateral flow assay.

    PubMed

    Kim, Cheonjung; Yoo, Yong Kyoung; Han, Sung Il; Lee, Junwoo; Lee, Dohwan; Lee, Kyungjae; Hwang, Kyo Seon; Lee, Kyu Hyoung; Chung, Seok; Lee, Jeong Hoon

    2017-07-11

    Paper-based analytical devices (e.g. lateral flow assays) are highly advantageous as portable diagnostic systems owing to their low costs and ease of use. Because of their low sensitivity and detection limits for biomolecules, these devices have several limitations in applications for real-field diagnosis. Here, we demonstrate a paper-based preconcentration enhanced lateral flow assay using a commercial β-hCG-based test. Utilizing a simple 9 V battery operation with a low power consumption of approximately 81 μW, we acquire a 25-fold preconcentration factor, demonstrating a clear sensitivity enhancement in the colorimetric lateral flow assay; consequently, clear colors are observed in a rapid kit test line, which cannot be monitored without preconcentration. This device can also facilitate a semi-quantitative platform using the saturation value and/or color intensity in both paper-based colorimetric assays and smartphone-based diagnostics.

  10. Ethical and clinical dilemmas in patients with head and neck tumors visiting a field hospital in the Philippines.

    PubMed

    Marom, Tal; Segal, David; Erlich, Tomer; Tsumi, Erez; Merin, Ofer; Lin, Guy

    2014-01-01

    To describe clinical and ethical dilemmas in patients presenting with head and neck (H&N) tumors to a field hospital in the "subacute" period following a typhoon. We retrospectively reviewed charts of H&N patients presenting to an integrated Israeli-Filipino medical facility, which was operated more than 11 days. Of the 1,844 adult patients examined, 85 (5 percent) presented with H&N tumors. Of those, 70 (82 percent) were females, with a mean age of 43 ± 15 years. Thyroid neoplasms were the most common tumors (68, 80 percent). Despite limited resources, we contributed to the workup and treatment of several patients. To better illustrate our dilemmas, we present four key patients, in whom we favored diagnostic/therapeutic interventions in two, and opted to defer any intervention in two. In a relief mission, despite the lack of clinical and pathological staging and questionable continuity of care, surgical interventions can be considered for therapeutic, palliative, and diagnostic purposes.

  11. CT Dose Optimization in Pediatric Radiology: A Multiyear Effort to Preserve the Benefits of Imaging While Reducing the Risks.

    PubMed

    Greenwood, Taylor J; Lopez-Costa, Rodrigo I; Rhoades, Patrick D; Ramírez-Giraldo, Juan C; Starr, Matthew; Street, Mandie; Duncan, James; McKinstry, Robert C

    2015-01-01

    The marked increase in radiation exposure from medical imaging, especially in children, has caused considerable alarm and spurred efforts to preserve the benefits but reduce the risks of imaging. Applying the principles of the Image Gently campaign, data-driven process and quality improvement techniques such as process mapping and flowcharting, cause-and-effect diagrams, Pareto analysis, statistical process control (control charts), failure mode and effects analysis, "lean" or Six Sigma methodology, and closed feedback loops led to a multiyear program that has reduced overall computed tomographic (CT) examination volume by more than fourfold and concurrently decreased radiation exposure per CT study without compromising diagnostic utility. This systematic approach involving education, streamlining access to magnetic resonance imaging and ultrasonography, auditing with comparison with benchmarks, applying modern CT technology, and revising CT protocols has led to a more than twofold reduction in CT radiation exposure between 2005 and 2012 for patients at the authors' institution while maintaining diagnostic utility. (©)RSNA, 2015.

  12. The business case for pediatric asthma quality improvement in low-income populations: examining a provider-based pay-for-reporting intervention.

    PubMed

    Reiter, Kristin L; Lemos, Kristin Andrews; Williams, Charlotte E; Esposito, Dominick; Greene, Sandra B

    2015-06-01

    To measure the return on investment (ROI) for a pediatric asthma pay-for-reporting intervention initiated by a Medicaid managed care plan in New York State. Practice-level, randomized prospective evaluation. Twenty-five primary care practices providing care to children enrolled in the Monroe Plan for Medical Care (the Monroe Plan). Practices were randomized to either treatment (13 practices, 11 participated) or control (12 practices). For each of its eligible members assigned to a treatment group practice, the Monroe plan paid a low monthly incentive fee to the practice. To receive the incentive, treatment group practices were required to conduct, and report to the Monroe Plan, the results of chart audits on eligible members. Chart audits were conducted by practices every 6 months. After each chart audit, the Monroe Plan provided performance feedback to each practice comparing its adherence to asthma care guidelines with averages from all other treatment group practices. Control practices continued with usual care. Intervention implementation and operating costs and per member, per month claims costs. ROI was measured by net present value (discounted cash flow analysis). The ROI to the Monroe Plan was negative, primarily due to high intervention costs and lack of reductions in spending on emergency department and hospital utilization for children in treatment relative to control practices. A pay-for-reporting, chart audit intervention is unlikely to achieve the meaningful reductions in utilization of high-cost services that would be necessary to produce a financial ROI in 2.5 years. © The Author 2015. Published by Oxford University Press in association with the International Society for Quality in Health Care; all rights reserved.

  13. Thermal Nonequilibrium in Hypersonic Separated Flow

    DTIC Science & Technology

    2014-12-22

    flow duration and steadiness. 15. SUBJECT TERMS Hypersonic Flowfield Measurements, Laser Diagnostics of Gas Flow, Laser Induced...extent than the NS computation. While it would be convenient to believe that the more physically realistic flow modeling of the DSMC gas - surface...index and absorption coefficient. Each of the curves was produced assuming a 0.5 % concentration of lithium at the Condition A nozzle exit conditions

  14. Changing climatic and anthropogenic influences on the Bermejo wetland, through archival documents - Mendoza, Argentina, 16th-20th centuries

    NASA Astrophysics Data System (ADS)

    Prieto, M. R.; Rojas, F.

    2011-11-01

    The wrong management of watering in the highest zones of the Mendoza northern oasis, the topography of the terrain and the deficient drainage, together with neotectonics phenomena, but mostly a dramatic and progressive increase of the Rio Mendoza flow volume originated the expansion of the wetlands area at the NE of the city of Mendoza at the turn of the 18th century, while in previous centuries it had retracted to a minimum. The area grew until reaching the dimension of large wetlands in the lowest oasis zones, resulting from a larger runoff and soil saturation by the rise of the phreatic layers. This situation remained throughout the 19th century, affecting the extension and use of the available land for human activity. The purpose of this study was to research this process that culminated in 1930 with the partial desiccation of the area. We have given particular importance to the influence of the climatic fluctuations in the Cordillera de los Andes and to the consequent variations of the Rio Mendoza flow volume in this process. For the analysis we used snowfall series at the cordillera and flow volume of the Rio Mendoza, built by Prieto (2009) with documental data. We analyzed which were the mediate and immediate consequences of the growth and later desiccation of the wetlands over the environment and its present repercussion on the ecosystem (salinization, poor soil drainage, soil alkalinization, sedimentation). In addition, we have also worked over georeferenced historic charts that partially reflect the behavior of the Cienaga del Bermejo during the 18th, 19th and 20th centuries. This behavior characterized by "growth pulses" and retraction moments is reflected in the analyzed charts, where those moments of major growth coincide with cycles of bigger snowstorms and larger flow volume in the Rio Mendoza.

  15. The misdiagnosis of bipolar disorder as a psychotic disorder: some of its causes and their influence on therapy.

    PubMed

    Meyer, Friederike; Meyer, Thomas D

    2009-01-01

    Looking at chart records bipolar disorder is often misdiagnosed as a psychotic disorder but no study has ever systematically looked into the reasons. One reason for misdiagnoses could be that clinicians use heuristics like the prototype approach in routine practice instead of strictly adhering to the diagnostic criteria. Using an experimental approach we investigated if the use of heuristics can explain when a diagnosis of psychotic disorder is given instead of bipolar disorder. We systematically varied information about the presence or absence of specific symptoms, i.e. hallucinations and decreased need for sleep during a manic episode. Experimentally varied case vignettes were randomly sent to psychiatrists in Southern Germany. The four versions of the case vignette all described the same person in a manic state and differed only in two aspects: the presence or absence of auditory hallucinations and of decreased need for sleep. The psychiatrists were asked to make a diagnosis, to rate their confidence in their diagnosis, and to recommend treatments. Almost half of the 142 psychiatrists (45%) did not diagnose bipolar disorder. Mentioning hallucinations decreased the likelihood of diagnosing bipolar disorder. The information about decreased need for sleep only affected the diagnosis significantly, if schizoaffective disorder was considered a bipolar disorder. Our results suggest that clinicians indeed use heuristics when making diagnostic decisions instead of strictly adhering to diagnostic criteria. More research is needed to better understand diagnostic decision making, especially under real life settings, and this might also be of interest when revising diagnostic manuals such as DSM.

  16. What Can We Learn About Karst Aquifer Heterogeneity From Pumping Tests

    NASA Astrophysics Data System (ADS)

    Marechal, J. C.; Dewandel, B.; Ladouche, B.; Fleury, P.

    2016-12-01

    Due to the complexity and duality of flows, well-test interpretation into karst systems constitutes a challenging task for hydrogeologists. This is especially true when the pumping well intersects karst heterogeneities such as the conduit network. The method of diagnostic plots, widely used in oil industry, can be applied to karst hydrogeology. In this paper, the classical response of a well-test into a karst conduit is described on a log-log drawdown derivative curve. It allows identifying successive flow regimes corresponding to the contribution of various karst aquifer subsystems (fractured matrix, karst conduit, main karst drainage network) to the pumped well. In heterogeneous karst systems, the log-log diagnostic plot of drawdown and its derivative in the pumping well can help identifying departures in flow-geometry from the classical homogeneous radial case. Classically, the diagnostic plot can be divided into several portions with: (a) early data used for identifying the karst conduit storage; (b) intermediate data for identifying the type of aquifer model that should be used (e.g. double porosity, anisotropy...); and (c) late data for identifying the possible boundaries. This is illustrated on three examples from Mediterranean karsts in southern France. A one-month duratio pumping test on a well intersecting the main karst drainage network of the Cent-Fonts karst system shows (i) a preliminary contribution of the karst conduit storage capacity followed by (ii) linear flows into the fractured matrix. A pumping test on a well intersecting a small karst conduit of the Corbières karst system shows the existence of (i) bi-linear flow within both the karst conduit and the fractured matrix at early times, followed by (ii) radial flows within the fractured matrix and (iii) finally the contribution of a major karst cavity. A two-months duration pumping test on a deep confined karst aquifer under low permeability rocks into the Gardanne basin shows the existence of no-flow boundary conditions due to the basin extension. The use of diagnostic plots allows identifying the various flow regimes during pumping tests, corresponding to the response of the individual karst aquifer subsystems. This is helpful for improving the understanding of the structure of the karst aquifer and flow exchanges between subsystems.

  17. Performance Analysis of the United States Marine Corps War Reserve Materiel Program Process Flow

    DTIC Science & Technology

    2016-12-01

    or Less)............41 Figure 21. Tornado Diagram of Expected Delays Using 2016 Inputs ........................42 x Figure 22. Fishbone Diagram of...variability. Using Crystal Ball we produced a Tornado Diagram (similar to a Pareto Chart) in order to tell us where to focus our efforts. The results of...the Tornado Diagram are shown in Figure 21. Figure 21. Tornado Diagram of Expected Delays Using 2016 Inputs Using the results shown in the Tornado

  18. Build Your Own Inventory System. Annual Cost: $100.00 (Approximate). Fixed Assets, Materials and Supplies. The Practical Elements for a Computerized, Continuing Inventory System in Schools and Use in Determining a Measure for Instructional Cost.

    ERIC Educational Resources Information Center

    Payne, Arnold, Comp.

    This publication presents performance flow charts and other accompanying forms that are elements of an economical computerized continuing inventory system. The system described here is intended to serve school systems as an adequate fixed asset system and to provide a computerized inventory model that offers support for costs of future educational…

  19. Chemically Modified Microelectrode Arrays. New Kinds of Electronic Devices.

    DTIC Science & Technology

    1987-08-05

    switching. Figure 1 shows a typical process for the fabrication of a microelectrode array consisting of eight, individually addressable Au (or Pt...S4r... -n - 2 ORGANIC CLEAN MRC SPUTTERING PHOTOLITHOGRAPHY _Suttred SI.N, & DRY ETCH _LorVO S1. 1.2 pm Figure 1. Flow chart for fabrication of...microelectrochemical devices, including polypyrrole, 14 poly(N-methylpyrrole), 14b poly(3-methylthiophene), 1 5 and polyaniline .15b,16 These materials can all be made by

  20. Study of quiet turbofan STOL aircraft for short-haul transportation. Volume 4: Markets

    NASA Technical Reports Server (NTRS)

    1973-01-01

    A marketing study to determine the acceptance and utilization of a STOL aircraft short-haul air transportation system was conducted. The relationship between STOL characteristics and the economic and social viability of STOL as a short-haul reliever system was examined. A study flow chart was prepared to show the city pair and traffic split analysis. The national demand for STOL aircraft, as well as the foreign and military markets, were analyzed.

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