Sample records for dies final project

  1. Identification and Characterization of Soluble Factors Involved in Delayed Effects of Low Dose Radiation. Final report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Baulch, Janet

    2013-09-11

    This is a 'glue grant' that was part of a DOE Low Dose project entitled 'Identification and Characterization of Soluble Factors Involved in Delayed Effects of Low Dose Radiation'. This collaborative program has involved Drs. David L. Springer from Pacific Northwest National Laboratory (PNNL), John H. Miller from Washington State University, Tri-cities (WSU) and William F. Morgan then from the University of Maryland, Baltimore (UMB). In July 2008, Dr. Morgan moved to PNNL and Dr. Janet E. Baulch became PI for this project at University of Maryland. In November of 2008, a one year extension with no new funds wasmore » requested to complete the proteomic analyses. The project stemmed from studies in the Morgan laboratory demonstrating that genomically unstable cells secret a soluble factor or factors into the culture medium, that cause cytogenetic aberrations and apoptosis in normal parental GM10115 cells. The purpose of this project was to identify the death inducing effect (DIE) factor or factors, estimate their relative abundance, identify the cell signaling pathways involved and finally recapitulate DIE in normal cells by exogenous manipulation of putative DIE factors in culture medium. As reported in detail in the previous progress report, analysis of culture medium from the parental cell line, and stable and unstable clones demonstrated inconsistent proteomic profiles as relate to candidate DIE factors. While the proposed proteomic analyses did not provide information that would allow DIE factors to be identified, the analyses provided another important set of observations. Proteomic analysis suggested that proteins associated with the cellular response to oxidative stress and mitochondrial function were elevated in the medium from unstable clones in a manner consistent with mitochondrial dysfunction. These findings correlate with previous studies of these clones that demonstrated functional differences between the mitochondria of stable and unstable clones. These mitochondrial abnormalities in the unstable clones contributes to oxidative stress.« less

  2. Resident reflections on end-of-life education: a mixed-methods study of the 3 Wishes Project

    PubMed Central

    Centofanti, J; Swinton, M; Dionne, J; Barefah, A; Boyle, A; Woods, A; Shears, M; Heels-Ansdell, D; Cook, D

    2016-01-01

    Objective The objectives of this study were to describe residents' experiences with end-of-life (EOL) education during a rotation in the intensive care unit (ICU), and to understand the possible influence of the 3 Wishes Project. Design We enrolled dying patients, their families and 1–3 of their clinicians in the 3 Wishes Project, eliciting and honouring a set of 3 wishes to bring peace to the final days of a critically ill patient's life, and ease the grieving process for families. We conducted semistructured interviews with 33 residents who had cared for 50 dying patients to understand their experiences with the project. Interviews were recorded, transcribed verbatim, then analysed using a qualitative descriptive approach. Setting 21-bed medical surgical ICU in a tertiary care, university-affiliated hospital. Results 33 residents participated from internal medicine (24, 72.7%), anaesthesia (8, 24.2%) and laboratory medicine (1, 3.0%) programmes in postgraduate years 1–3. 3 categories and associated themes emerged. (1) EOL care is a challenging component of training in that (a) death in the ICU can invoke helplessness, (b) EOL education is inadequate, (c) personal connections with dying patients is difficult in the ICU and (d) EOL skills are valued by residents. (2) The project reframes the dying process for residents by (a) humanising this aspect of practice, (b) identifying that family engagement is central to the dying process, (c) increasing emotional responsiveness and (d) showing that care shifts, not stops. (3) The project offers experiential education by (a) intentional role modelling, (b) facilitating EOL dialogue, (c) empowering residents to care in a tangible way and (d) encouraging reflection. Conclusions For residents, the 3 Wishes Project integrated many forms of active learning for residents. Practice-based rather than classroom-based programmes may engage trainees to develop EOL skills transferable to other settings. PMID:27033962

  3. Resident reflections on end-of-life education: a mixed-methods study of the 3 Wishes Project.

    PubMed

    Centofanti, J; Swinton, M; Dionne, J; Barefah, A; Boyle, A; Woods, A; Shears, M; Heels-Ansdell, D; Cook, D

    2016-03-31

    The objectives of this study were to describe residents' experiences with end-of-life (EOL) education during a rotation in the intensive care unit (ICU), and to understand the possible influence of the 3 Wishes Project. We enrolled dying patients, their families and 1-3 of their clinicians in the 3 Wishes Project, eliciting and honouring a set of 3 wishes to bring peace to the final days of a critically ill patient's life, and ease the grieving process for families. We conducted semistructured interviews with 33 residents who had cared for 50 dying patients to understand their experiences with the project. Interviews were recorded, transcribed verbatim, then analysed using a qualitative descriptive approach. 21-bed medical surgical ICU in a tertiary care, university-affiliated hospital. 33 residents participated from internal medicine (24, 72.7%), anaesthesia (8, 24.2%) and laboratory medicine (1, 3.0%) programmes in postgraduate years 1-3. 3 categories and associated themes emerged. (1) EOL care is a challenging component of training in that (a) death in the ICU can invoke helplessness, (b) EOL education is inadequate, (c) personal connections with dying patients is difficult in the ICU and (d) EOL skills are valued by residents. (2) The project reframes the dying process for residents by (a) humanising this aspect of practice, (b) identifying that family engagement is central to the dying process, (c) increasing emotional responsiveness and (d) showing that care shifts, not stops. (3) The project offers experiential education by (a) intentional role modelling, (b) facilitating EOL dialogue, (c) empowering residents to care in a tangible way and (d) encouraging reflection. For residents, the 3 Wishes Project integrated many forms of active learning for residents. Practice-based rather than classroom-based programmes may engage trainees to develop EOL skills transferable to other settings. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

  4. Personalizing death in the intensive care unit: the 3 Wishes Project: a mixed-methods study.

    PubMed

    Cook, Deborah; Swinton, Marilyn; Toledo, Feli; Clarke, France; Rose, Trudy; Hand-Breckenridge, Tracey; Boyle, Anne; Woods, Anne; Zytaruk, Nicole; Heels-Ansdell, Diane; Sheppard, Robert

    2015-08-18

    Dying in the complex, efficiency-driven environment of the intensive care unit can be dehumanizing for the patient and have profound, long-lasting consequences for all persons attendant to that death. To bring peace to the final days of a patient's life and to ease the grieving process. Mixed-methods study. 21-bed medical-surgical intensive care unit. Dying patients and their families and clinicians. To honor each patient, a set of wishes was generated by patients, family members, or clinicians. The wishes were implemented before or after death by patients, families, clinicians (6 of whom were project team members), or the project team. Quantitative data included demographic characteristics, processes of care, and scores on the Quality of End-of-Life Care-10 instrument. Semistructured interviews of family members and clinicians were transcribed verbatim, and qualitative description was used to analyze them. Participants included 40 decedents, at least 1 family member per patient, and 3 clinicians per patient. The 159 wishes were implemented and classified into 5 categories: humanizing the environment, tributes, family reconnections, observances, and "paying it forward." Scores on the Quality of End-of-Life Care-10 instrument were high. The central theme from 160 interviews of 170 persons was how the 3 Wishes Project personalized the dying process. For patients, eliciting and customizing the wishes honored them by celebrating their lives and dignifying their deaths. For families, it created positive memories and individualized end-of-life care for their loved ones. For clinicians, it promoted interprofessional care and humanism in practice. Impaired consciousness limited understanding of patients' viewpoints. The 3 Wishes Project facilitated personalization of the dying process through explicit integration of palliative and spiritual care into critical care practice. Hamilton Academy of Health Science Research Organization, Canadian Intensive Care Foundation.

  5. Werner Jaeger's "Paideia" and His 'Third Humanism'

    ERIC Educational Resources Information Center

    Horn, Christoph

    2018-01-01

    Werner Jaeger (1888-1961) was at his time the most brilliant and the most influential German classicist. His most important project was a tripartite study that he finally published under the title of "Paideia. Die Formung des griechischen Menschen" (1933-1947). "Paideia" was much more than a detailed scholarly book on pedagogy…

  6. Systems Integration, Analysis and Modeling Support to the HEDS Technology/Commercialization Initiative (HTCI)

    NASA Technical Reports Server (NTRS)

    Feingold, Harvey; ONeil, Dan (Technical Monitor)

    2002-01-01

    In response to a recommendation from OMB, NASA's Fiscal Year 2001 budget included a new program within the HEDS (Human Exploration and Development of Space) Enterprise called HEDS Technology/ Commercialization Initiative (HTCI). HTCI had three overarching goals: to support REDS analysis and planning for safe, affordable and effective future programs and projects that advance human exploration, scientific discovery, and the commercial development of space; to pursue research, development, and validation of breakthrough technologies and highly innovative systems concepts; and to advance die creation of strong partnerships within NASA, with U.S. industry and universities, and internationally. As part of its contracted effort, SAIC was to write a report contribution, describing die results of its task activities, to a final HTCI report prepared by MSFC. Unfortunately, government cancellation of the HTCI program in the summer of 2001 curtailed all efforts on the program including die Final HTCI report. In the absence of that report, SAIC has issued this final report in an attempt to document some of the technical material it produced. The report contains SAIC presentations for both HTCI workshops; a set of roadmap charts for the Systems Analysis, Integration and Modeling; and charts showing the evolution of the current TITAN modeling architecture.

  7. Complex deformation routes for direct recycling aluminium alloy scrap via industrial hot extrusion

    NASA Astrophysics Data System (ADS)

    Paraskevas, Dimos; Kellens, Karel; Kampen, Carlos; Mohammadi, Amirahmad; Duflou, Joost R.

    2018-05-01

    This paper presents the final results of an industrial project, aiming for direct hot extrusion of wrought aluminium alloy scrap at an industrial scale. Two types of complex deformation/extrusion routes were tested for the production of the same profile, starting from AA6060 scrap in form of machining chips. More specifically scrap-based billets were extruded through: a 2-porthole and a 4-porthole die-set, modified for enhanced scrap consolidation and grain refinement. For comparison reasons, cast billets of the same alloy were extruded through the modified 2-porthole die set. The tensile testing results as well as microstructural investigations show that the 4-porthole extrusion route further improves scrap consolidation compared to the 2-porthole die output. The successful implementation of solid state recycling, directly at industrial level, indicates the technological readiness level of this research.

  8. Lights! Camera! Action Projects! Engaging Psychopharmacology Students in Service-based Action Projects Focusing on Student Alcohol Abuse

    PubMed Central

    Kennedy, Susan

    2016-01-01

    Alcohol abuse continues to be an issue of major concern for the health and well-being of college students. Estimates are that over 80% of college students are involved in the campus “alcohol culture.” Annually, close to 2000 students die in the United States due to alcohol-related accidents, with another 600,000 sustaining injury due to alcohol-related incidents (NIAAA, 2013). Students enrolled in a Psychopharmacology course engaged in action projects (community outreach) focused on alcohol abuse on our campus. Research has indicated that these types of projects can increase student engagement in course material and foster important skills, including working with peers and developing involvement in one’s community. This paper describes the structure and requirements of five student outreach projects and the final projects designed by the students, summarizes the grading and assessment of the projects, and discusses the rewards and challenges of incorporating such projects into a course. PMID:27385923

  9. Lights! Camera! Action Projects! Engaging Psychopharmacology Students in Service-based Action Projects Focusing on Student Alcohol Abuse.

    PubMed

    Kennedy, Susan

    2016-01-01

    Alcohol abuse continues to be an issue of major concern for the health and well-being of college students. Estimates are that over 80% of college students are involved in the campus "alcohol culture." Annually, close to 2000 students die in the United States due to alcohol-related accidents, with another 600,000 sustaining injury due to alcohol-related incidents (NIAAA, 2013). Students enrolled in a Psychopharmacology course engaged in action projects (community outreach) focused on alcohol abuse on our campus. Research has indicated that these types of projects can increase student engagement in course material and foster important skills, including working with peers and developing involvement in one's community. This paper describes the structure and requirements of five student outreach projects and the final projects designed by the students, summarizes the grading and assessment of the projects, and discusses the rewards and challenges of incorporating such projects into a course.

  10. Using artificial neural networks to model aluminium based sheet forming processes and tools details

    NASA Astrophysics Data System (ADS)

    Mekras, N.

    2017-09-01

    In this paper, a methodology and a software system will be presented concerning the use of Artificial Neural Networks (ANNs) for modeling aluminium based sheet forming processes. ANNs models’ creation is based on the training of the ANNs using experimental, trial and historical data records of processes’ inputs and outputs. ANNs models are useful in cases that processes’ mathematical models are not accurate enough, are not well defined or are missing e.g. in cases of complex product shapes, new material alloys, new process requirements, micro-scale products, etc. Usually, after the design and modeling of the forming tools (die, punch, etc.) and before mass production, a set of trials takes place at the shop floor for finalizing processes and tools details concerning e.g. tools’ minimum radii, die/punch clearance, press speed, process temperature, etc. and in relation with the material type, the sheet thickness and the quality achieved from the trials. Using data from the shop floor trials and forming theory data, ANNs models can be trained and created, and can be used to estimate processes and tools final details, hence supporting efficient set-up of processes and tools before mass production starts. The proposed ANNs methodology and the respective software system are implemented within the EU H2020 project LoCoMaTech for the aluminium-based sheet forming process HFQ (solution Heat treatment, cold die Forming and Quenching).

  11. Development of an Innovative Laser-Assisted Coating Process for Extending Lifetime of Metal Casting Dies. Final Report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Madhav Rao Gonvindaraju

    1999-10-18

    Die casting dies used in the metal casting industry fail due to thermal fatigue cracking accompanied by the presence of residual tensile stresses, corrosion, erosion and wear of die surfaces. This phase 1 SBIR Final Report summarize Karta Technologies research involving the development of an innovative laser coating technology for metal casting dies. The process involves depositing complex protective coatings of nanocrystalline powders of TiC followed by a laser shot peening. The results indicate a significant improvement in corrosion and erosion resistance in molten aluminum for H13 die casting die steels. The laser-coated samples also showed improved surface finish, amore » homogeneous and uniform coating mircrostructure. The technology developed in this research can have a significant impact on the casting industry by saving the material costs involved in replacing dies, reducing downtime and improving the quality.« less

  12. Assessing the Quality of Death and Dying in an Integrated Health Care System in Rural Pennsylvania.

    PubMed

    Darer, Jonathan D; Clarke, Deseraé N; Sees, Amanda C; Berger, Andrea L; Kirchner, H Lester; Stametz, Rebecca A; Davis, Daniel

    2015-09-01

    With growing emphasis on improving the value of health care, there is increased scrutiny of quality outcomes and high health expenditures during the final months of life. The purpose of this project is to answer 1) how do next of kin (NOK) perceive the quality of their loved ones' dying and death; 2) are there patient and NOK characteristics that predict lower quality; and 3) are there structural aspects of care associated with lower quality? A mailed survey was administered to a stratified random sample of NOK of Geisinger Health System patients who had died in the past year. The Quality of Death and Dying, the General Anxiety Disorder seven-item scale, the Patient Health Questionnaire eight-item depression scale, and selected questions from the Toolkit of Instruments to Measure End of Life Care were used. There were 672 respondents. Significant predictors of Quality of Death and Dying score were number of doctors involved in care (P = 0.0415), location of death (P < 0.0001), frequency of receiving confusing or contradictory information (P < 0.0001), illness progression (P = 0.0343), Patient Health Questionnaire-2 score (P = 0.0148), and General Anxiety Disorder seven-item scale score (P < 0.0070). Several findings suggest that factors such as NOK depression and anxiety, prolonged illness, dying in the hospital, receipt of conflicting information, and confusion around the doctor in charge are associated with lower quality of the dying and death experience for NOK. Further investigation is warranted to facilitate high-quality measurement and the use of measurement results to improve care. Copyright © 2015 American Academy of Hospice and Palliative Medicine. Published by Elsevier Inc. All rights reserved.

  13. Optimization of Composition and Heat Treating of Die Steels for Extended Lifetime

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    David Schwam; John F. Wallace; Quanyou Zhou

    2002-01-30

    An ''average'' die casting die costs fifty thousand dollars. A die used in making die cast aluminum engine blocks can cost well over one million dollars. These costs provide a strong incentive for extension of die life. While vacuum quenched Premium Grade H13 dies have become the most widely used in the United States, tool makers and die casters are constantly searching for new steels and heat treating procedures to extend die life. This project was undertaken to investigate the effects of composition and heat treating on die life and optimize these parameters.

  14. A Generalized Escape System Simulation (GESS) Computer Program. Volume 2. GESS Programmer’s Manual. Version II.

    DTIC Science & Technology

    1984-04-01

    Directorate (Code 6032) V NAVAL AIR DEVELOPMENT CENTER Warminster, PA 18974 and I David A. Fender KETRON. INC. Warminster, PA 18974 DTlC APRIL 1984 ELECTE FINAL...A. D’Aulerio N62269-81-Z-0206 David A. Fender Task No. 630-1944 9. PERFORMING ORGANIZATION NAME AND ADDRESS 10. PROGRAM ELEMEN1T PROJECT, TASKAREA A...0102LF01401UNCLASSIFIED SECURITY CLAWFICATION OF TNIS PAGE (011t1 Die pewed) UNCLASSIFIED SECURITY CLASSIFICATION OF THIS PAGE w JIMu D#& Ent:ed) 9. Continued Louis A

  15. A Retrospective Medical Records Review of Risk Factors for the Development of Respiratory Tract Secretions (Death Rattle) in the Dying Patient.

    PubMed

    Kolb, Hildegard; Snowden, Austyn; Stevens, Elaine; Atherton, Iain

    2018-05-09

    Identification of risk factors predicting the development of death rattle. Respiratory tract secretions, often called death rattle, are among the most common symptoms in dying patients around the world. It is unknown whether death rattle causes distress in patients, but it has been globally reported that distress levels can be high in family members. Although there is a poor evidence base, treatment with antimuscarinic medication is standard practice worldwide and prompt intervention is recognised as crucial for effectiveness. The identification of risk factors for the development of death rattle would allow for targeted interventions. A case ̶ control study was designed to retrospectively review two hundred consecutive medical records of mainly cancer patients who died in a hospice inpatient setting between 2009 - 2011. Fifteen potential risk factors including the original factors weight, smoking, final opioid dose and final Midazolam dose were investigated. Binary logistic regression to identify risk factors for death rattle development. Univariate analysis showed death rattle was significantly associated with final Midazolam doses and final opioid doses, length of dying phase and anticholinergic drug load in the pre-terminal phase. In the final logistic regression model only Midazolam was statistically significant and only at final doses of 20 mg/24hrs or over (OR 3.81 CI 1.41-10.34). Dying patients with a requirement for a high dose of Midazolam have an increased likelihood of developing death rattle. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.

  16. 38 CFR 11.128 - Veteran dies without having filed application for final settlement.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Application for Payment of Adjusted Service Certificate Under the World War Adjusted Compensation Act, As... 38 Pensions, Bonuses, and Veterans' Relief 1 2013-07-01 2013-07-01 false Veteran dies without having filed application for final settlement. 11.128 Section 11.128 Pensions, Bonuses, and Veterans...

  17. 38 CFR 11.128 - Veteran dies without having filed application for final settlement.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Application for Payment of Adjusted Service Certificate Under the World War Adjusted Compensation Act, As... 38 Pensions, Bonuses, and Veterans' Relief 1 2011-07-01 2011-07-01 false Veteran dies without having filed application for final settlement. 11.128 Section 11.128 Pensions, Bonuses, and Veterans...

  18. 38 CFR 11.128 - Veteran dies without having filed application for final settlement.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Application for Payment of Adjusted Service Certificate Under the World War Adjusted Compensation Act, As... 38 Pensions, Bonuses, and Veterans' Relief 1 2014-07-01 2014-07-01 false Veteran dies without having filed application for final settlement. 11.128 Section 11.128 Pensions, Bonuses, and Veterans...

  19. 38 CFR 11.128 - Veteran dies without having filed application for final settlement.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Application for Payment of Adjusted Service Certificate Under the World War Adjusted Compensation Act, As... 38 Pensions, Bonuses, and Veterans' Relief 1 2010-07-01 2010-07-01 false Veteran dies without having filed application for final settlement. 11.128 Section 11.128 Pensions, Bonuses, and Veterans...

  20. 38 CFR 11.128 - Veteran dies without having filed application for final settlement.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Application for Payment of Adjusted Service Certificate Under the World War Adjusted Compensation Act, As... 38 Pensions, Bonuses, and Veterans' Relief 1 2012-07-01 2012-07-01 false Veteran dies without having filed application for final settlement. 11.128 Section 11.128 Pensions, Bonuses, and Veterans...

  1. Differential Die-Away Instrument: Report on Fuel Assembly Mock-up Measurements with Neutron Generator

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Goodsell, Alison Victoria; Swinhoe, Martyn Thomas; Henzl, Vladimir

    2014-09-18

    Fresh fuel experiments for the differential die-away (DDA) project were performed using a DT neutron generator, a 15x15 PWR fuel assembly, and nine 3He detectors in a water tank inside of a shielded cell at Los Alamos National Laboratory (LANL). Eight different fuel enrichments were created using low enriched (LEU) and depleted uranium (DU) dioxide fuel rods. A list-mode data acquisition system recorded the time-dependent signal and analysis of the DDA signal die-away time was performed. The die-away time depended on the amount of fissile material in the fuel assembly and the position of the detector. These experiments were performedmore » in support of the spent nuclear fuel Next Generation Safeguards Initiative DDA project. Lessons learned from the fresh fuel DDA instrument experiments and simulations will provide useful information to the spent fuel project.« less

  2. Projecting health-care expenditure for Switzerland: further evidence against the 'red-herring' hypothesis.

    PubMed

    Colombier, Carsten; Weber, Werner

    2011-01-01

    This paper contributes to the debate about the impact of population ageing on health-care (HC) expenditure. Some health economists claim that the commonly presumed impact of population ageing is a 'red herring'. Based on empirical studies, these authors conclude that proximity to death and not age per se matters. In projecting HC expenditure for Switzerland, the present study provides evidence that proximity to death is of marginal importance. These projections suggest that population ageing is still the most important age-related cost-driver. Moreover, morbidity outweighs mortality as a factor of HC expenditure. But most vital are non-demographic drivers such as medical progress. Thus, from the point of view of cost-benefit analysis one should even ignore costs of dying when projecting HC expenditure. Moreover, regressions might overestimate proximity to death due to systematic biases. Finally, ever-increasing HC expenditure can be slowed down by appropriate policy measures. Copyright © 2010 John Wiley & Sons, Ltd.

  3. Dying comfortably in very old age with or without dementia in different care settings - a representative "older old" population study.

    PubMed

    Fleming, Jane; Calloway, Rowan; Perrels, Anouk; Farquhar, Morag; Barclay, Stephen; Brayne, Carol

    2017-10-05

    Comfort is frequently ranked important for a good death. Although rising numbers of people are dying in very old age, many with dementia, little is known about symptom control for "older old" people or whether care in different settings enables them to die comfortably. This study aims to examine, in a population-representative sample, associations between factors potentially related to reported comfort during very old people's final illness: physical and cognitive disability, place of care and transitions in their final illness, and place of death. Retrospective analyses linked three data sources for n = 180 deceased study participants (68% women) aged 79-107 in a representative population-based UK study, the Cambridge City over-75s Cohort (CC75C): i) prospective in-vivo dementia diagnoses and cognitive assessments, ii) certified place of death records, iii) data from interviews with relatives/close carers including symptoms and "How comfortable was he/she in his/her final illness?" In the last year of life 83% were disabled in basic activities, 37% had moderate/severe dementia and 45% minimal/mild dementia or cognitive impairment. Regardless of dementia/cognitive status, three-quarters died following a final illness lasting a week or longer. 37%, 44%, 13% and 7% of the deceased were described as having been "very comfortable", "comfortable", "fairly comfortable" or "uncomfortable" respectively during their final illness, but reported symptoms were common: distress, pain, depression and delirium or confusion each affected 40-50%. For only 10% were no symptoms reported. There were ≥4-fold increased odds of dying comfortably associated with being in a care home during the final illness, dying in a care home, and with staying in place (dying at what death certificates record as "usual address"), whether home or care home, compared with hospital, but no significant association with disability or dementia/cognitive status, regardless of adjustment. These findings are consistent with reports that care homes can provide care akin to hospice for the very old and support an approach of supporting residents to stay in their care home or own home if possible. Findings on reported high prevalence of multiple symptoms can inform policy and training to improve older old people's end-of-life care in all settings.

  4. Die Starter: A New System to Manage Early Feasibility in Sheet Metal Forming

    NASA Astrophysics Data System (ADS)

    Narainen, Rodrigue; Porzner, Harald

    2016-08-01

    Die Starter, a new system developed by ESI Group, allows the user to drastically reduce the number of iterations during the early tool process feasibility. This innovative system automatically designs the first quick die face, generating binder and addendum surfaces (NURBS surfaces) by taking account the full die process. Die Starter also improves the initial die face based on feasibility criteria (avoiding splits, wrinkles) by automatically generating the geometrical modifications of the binder and addendum and the bead restraining forces with minimal material usage. This paper presents a description of the new system and the methodology of Die Starter. Some industrial examples are presented from the part geometry to final die face including automatic developed flanges, part on binder and inner binder.

  5. Simulation-Driven Design Approach for Design and Optimization of Blankholder

    NASA Astrophysics Data System (ADS)

    Sravan, Tatipala; Suddapalli, Nikshep R.; Johan, Pilthammar; Mats, Sigvant; Christian, Johansson

    2017-09-01

    Reliable design of stamping dies is desired for efficient and safe production. The design of stamping dies are today mostly based on casting feasibility, although it can also be based on criteria for fatigue, stiffness, safety, economy. Current work presents an approach that is built on Simulation Driven Design, enabling Design Optimization to address this issue. A structural finite element model of a stamping die, used to produce doors for Volvo V70/S80 car models, is studied. This die had developed cracks during its usage. To understand the behaviour of stress distribution in the stamping die, structural analysis of the die is conducted and critical regions with high stresses are identified. The results from structural FE-models are compared with analytical calculations pertaining to fatigue properties of the material. To arrive at an optimum design with increased stiffness and lifetime, topology and free-shape optimization are performed. In the optimization routine, identified critical regions of the die are set as design variables. Other optimization variables are set to maintain manufacturability of the resultant stamping die. Thereafter a CAD model is built based on geometrical results from topology and free-shape optimizations. Then the CAD model is subjected to structural analysis to visualize the new stress distribution. This process is iterated until a satisfactory result is obtained. The final results show reduction in stress levels by 70% with a more homogeneous distribution. Even though mass of the die is increased by 17 %, overall, a stiffer die with better lifetime is obtained. Finally, by reflecting on the entire process, a coordinated approach to handle such situations efficiently is presented.

  6. Design and Analysis of a Forging Die for Manufacturing of Multiple Connecting Rods

    NASA Astrophysics Data System (ADS)

    Megharaj, C. E.; Nagaraj, P. M.; Jeelan Pasha, K.

    2016-09-01

    This paper demonstrates to utilize the hammer capacity by modifying the die design such that forging hammer can manufacture more than one connecting rod in a given forging cycle time. To modify the die design study is carried out to understand the parameters that are required for forging die design. By considering these parameters, forging die is designed using design modelling tool solid edge. This new design now can produce two connecting rods in same capacity hammer. The new design is required to validate by verifying complete filing of metal in die cavities without any defects in it. To verify this, analysis tool DEFORM 3D is used in this project. Before start of validation process it is require to convert 3D generated models in to. STL file format to import the models into the analysis tool DEFORM 3D. After importing these designs they are analysed for material flow into the cavities and energy required to produce two connecting rods in new forging die design. It is found that the forging die design is proper without any defects and also energy graph shows that the forging energy required to produce two connecting rods is within the limit of that hammer capacity. Implementation of this project increases the production of connecting rods by 200% in less than previous cycle time.

  7. Death and help expected from nurses when dying.

    PubMed

    Shih, Fu-Jin; Gau, Meei-Ling; Lin, Yaw-Sheng; Pong, Suang-Jing; Lin, Hung-Ru

    2006-07-01

    This project was undertaken to ascertain the perceptions of a group of Taiwan's fourth-year bachelor of science in nursing (BSN) students regarding death and help expected from nurses during the dying process. Within the Chinese culture, death is one of the most important life issues. However, in many Chinese societies it is difficult for people to reveal their deepest feelings to their significant others or loved ones. It was in this context that this project was developed because little is known about how Taiwan's nursing students perceive death and the dying process. Using an open-ended, self-report questionnaire, 110 senior BSN students recorded their thoughts on: (1) their fears before physical death; (2) afterlife destinations; and (3) the help they would expect from nurses when dying. The data were analyzed using a three-layer qualitative thematic analysis. The students' reported needs during the dying process were directed towards three main goals: (1) help in reaching the 'triple targets of individual life'; (2) help in facilitating in-depth support so that both the dying person and significant others can experience a blessed farewell; and (3) help in reaching a destination in the afterlife. The results support the belief of dying as a transition occurring when life weans itself from the mortal world and prepares for an afterlife.

  8. A free gingival impression for achieving optimal interdental papilla height: a case report.

    PubMed

    Nozawa, Takeshi; Kitami, Norikazu; Tsurumaki, Shunzo; Enomoto, Hiroaki; Ito, Koichi

    2011-02-01

    Failure to tend to inadequate crown contours in the crown trial can cause long-term disharmony of the free gingival form. This case report describes a novel technique for free gingival impression from a final provisional restoration to a zirconia crown. Two die casts were manufactured from a silicone impression. The first die cast was for the zirconia crown; the second die cast was for the final provisional restoration and the provisionalized transfer coping. A free gingival impression was taken using a provisionalized transfer coping, and a soft gingival model was manufactured. The proximal contact position was managed using the predicted convex curve of the interdental papillae. One year after zirconia crown placement, no inflammation was observed around the pyramidal interdental papillae, and symmetric interdental papilla heights were evident. A free gingival impression using a two die-cast technique appears to be useful for achieving optimal interdental papilla height.

  9. Energy Saving Melting and Revert Reduction Technology: Improved Die Casting Process to Preserve the Life of the Inserts

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    David Schwam, PI; Xuejun Zhu, Sr. Research Associate

    2012-09-30

    The goal of this project was to study the combined effects of die design, proper internal cooling and efficient die lubricants on die life. The project targeted improvements in die casting insert life by: Optomized Die Design for Reduced Surface Temperature: The life of die casting dies is significantly shorter when the die is exposed to elevated temperature for significant periods of time. Any die operated under conditions leading to surface temperature in excess of 1050oF undergoes structural changes that reduce its strength. Optimized die design can improve die life significantly. This improvement can be accomplished by means of coolingmore » lines, baffles and bubblers in the die. A key objective of the project was to establish criteria for the minimal distance of the cooling lines from the surface. This effort was supported with alloys and machining by BohlerUddeholm, Dunn Steel, HH Stark and Rex Buckeye. In plant testing and evaluation was conducted as in-kind cost share at St. Clair Die Casting. The Uddeholm Dievar steel evaluated in this program showed superior resistance to thermal fatigue resistance. Based on the experimental evidence, cooling lines could be placed as close as 0.5" from the surface. Die Life Extension by Optimized Die Lubrication: The life of die casting dies is affected by additions made to its surface with the proper lubricants. These lubricants will protect the surface from the considerable temperature peaks that occur when the molten melt enters the die. Dies will reach a significantly higher temperature without this lubricant being applied. The amount and type of the lubricant are critical variables in the die casting process. However, these lubricants must not corrode the die surface. This effort was supported with alloys and machining by BohlerUddeholm, Dunn Steel, HH Stark and Rex Buckeye. In plant testing and evaluation was conducted as in-kind cost share at St. Clair Die Casting. Chem- Trend participated in the program with die lubricants and technical support. Experiments conducted with these lubricants demonstrated good protection of the substrate steel. Graphite and boron nitride used as benchmarks are capable of completely eliminating soldering and washout. However, because of cost and environmental considerations these materials are not widely used in industry. The best water-based die lubricants evaluated in this program were capable of providing similar protection from soldering and washout. In addition to improved part quality and higher production rates, improving die casting processes to preserve the life of the inserts will result in energy savings and a reduction in environmental wastes. Improving die life by means of optimized cooling line placement, baffles and bubblers in the die will allow for reduced die temperatures during processing, saving energy associated with production. The utilization of optimized die lubricants will also reduce heat requirements in addition to reducing waste associated with soldering and washout. This new technology was predicted to result in an average energy savings of 1.1 trillion BTU's/year over a 10 year period. Current (2012) annual energy saving estimates, based on commercial introduction in 2010, a market penetration of 70% by 2020 is 1.26 trillion BTU's/year. Along with these energy savings, reduction of scrap and improvement in casting yield will result in a reduction of the environmental emissions associated with the melting and pouring of the metal which will be saved as a result of this technology. The average annual estimate of CO2 reduction per year through 2020 is 0.025 Million Metric Tons of Carbon Equivalent (MM TCE).« less

  10. Wrinkle-Free Hydroforming of Wire Mesh

    NASA Technical Reports Server (NTRS)

    Fadness, J.

    1986-01-01

    Plastic films lubricate workpiece so it deforms smoothly. Thin layers of plastic below top die and above bottom die ensure wire screen slides as shaped by hydroforming. Plastic layers are 0.0043 in. (0.11 m) thick. Preformed to contours of dies and final workpiece. New method of hydroforming fine-wire-mesh heat-shield screens eliminates wrinkles and marks. Prevents screen from being damaged and pores from becoming blocked.

  11. Microstructures and properties of aluminum die casting alloys

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    M. M. Makhlouf; D. Apelian; L. Wang

    1998-10-01

    This document provides descriptions of the microstructure of different aluminum die casting alloys and to relate the various microstructures to the alloy chemistry. It relates the microstructures of the alloys to their main engineering properties such as ultimate tensile strength, yield strength, elongation, fatigue life, impact resistance, wear resistance, hardness, thermal conductivity and electrical conductivity. Finally, it serves as a reference source for aluminum die casting alloys.

  12. High-Strength Aluminum Casting Alloy for High-Temperature Applications (MSFC Center Director's Discretionary Fund Final Project No. 97-10)

    NASA Technical Reports Server (NTRS)

    Lee, J. A.

    1998-01-01

    A new aluminum-silicon alloy has been successfully developed at Marshall Space Flight Center that has a significant improvement in tensile strength at elevated temperatures (550 to 700 F). For instance, the new alloy shows in average tensile strength of at least 90 percent higher than the current 390 aluminum piston alloy tested at 500 F. Compared to conventional aluminum alloys, automotive engines using the new piston alloy will have improved gas mileage, and may produce less air pollution in order to meet the future U.S. automotive legislative requirements for low hydrocarbon emissions. The projected cost for this alloy is less than $0.95/lb, and it readily allows the automotive components to be cast at a high production volume with a low, fully accounted cost. It is economically produced by pouring molten metal directly into conventional permanent steel molds or die casting.

  13. Numerical simulation and experiment on effect of ultrasonic in polymer extrusion processing

    NASA Astrophysics Data System (ADS)

    Wan, Yue; Fu, ZhiHong; Wei, LingJiao; Zang, Gongzheng; Zhang, Lei

    2018-01-01

    The influence of ultrasonic wave on the flow field parameters and the precision of extruded products are studied. Firstly, the effect of vibration power on the average velocity of the outlet, the average viscosity of the die section, the average shear rate and the inlet pressure of the die section were studied by using the Polyflow software. Secondly, the effects of ultrasonic strength on the die temperature and the drop of die pressure were studied experimentally by different head temperature and different screw speed. Finally, the relationship between die pressure and extrusion flow rate under different ultrasonic power were studied through experiments.

  14. The roles of hydraulic and carbon stress in a widespread climate-induced forest die-off

    PubMed Central

    Anderegg, William R. L.; Berry, Joseph A.; Smith, Duncan D.; Sperry, John S.; Anderegg, Leander D. L.; Field, Christopher B.

    2012-01-01

    Forest ecosystems store approximately 45% of the carbon found in terrestrial ecosystems, but they are sensitive to climate-induced dieback. Forest die-off constitutes a large uncertainty in projections of climate impacts on terrestrial ecosystems, climate–ecosystem interactions, and carbon-cycle feedbacks. Current understanding of the physiological mechanisms mediating climate-induced forest mortality limits the ability to model or project these threshold events. We report here a direct and in situ study of the mechanisms underlying recent widespread and climate-induced trembling aspen (Populus tremuloides) forest mortality in western North America. We find substantial evidence of hydraulic failure of roots and branches linked to landscape patterns of canopy and root mortality in this species. On the contrary, we find no evidence that drought stress led to depletion of carbohydrate reserves. Our results illuminate proximate mechanisms underpinning recent aspen forest mortality and provide guidance for understanding and projecting forest die-offs under climate change. PMID:22167807

  15. Energy-Saving Melting and Revert Reduction Technology (E-SMARRT): Use of Laser Engineered Net Shaping for Rapid Manufacturing of Dies with Protective Coatings and Improved Thermal Management

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Brevick, Jerald R.

    2014-06-13

    In the high pressure die casting process, molten metal is introduced into a die cavity at high pressure and velocity, enabling castings of thin wall section and complex geometry to be obtained. Traditional die materials have been hot work die steels, commonly H13. Manufacture of the dies involves machining the desired geometry from monolithic blocks of annealed tool steel, heat treating to desired hardness and toughness, and final machining, grinding and polishing. The die is fabricated with internal water cooling passages created by drilling. These materials and fabrication methods have been used for many years, however, there are limitations. Toolmore » steels have relatively low thermal conductivity, and as a result, it takes time to remove the heat from the tool steel via the drilled internal water cooling passages. Furthermore, the low thermal conductivity generates large thermal gradients at the die cavity surfaces, which ultimately leads to thermal fatigue cracking on the surfaces of the die steel. The high die surface temperatures also promote the metallurgical bonding of the aluminum casting alloy to the surface of the die steel (soldering). In terms of process efficiency, these tooling limitations reduce the number of die castings that can be made per unit time by increasing cycle time required for cooling, and increasing downtime and cost to replace tooling which has failed either by soldering or by thermal fatigue cracking (heat checking). The objective of this research was to evaluate the feasibility of designing, fabricating, and testing high pressure die casting tooling having properties equivalent to H13 on the surface in contact with molten casting alloy - for high temperature and high velocity molten metal erosion resistance – but with the ability to conduct heat rapidly to interior water cooling passages. A layered bimetallic tool design was selected, and the design evaluated for thermal and mechanical performance via finite element analysis. H13 was retained as the exterior layer of the tooling, while commercially pure copper was chosen for the interior structure of the tooling. The tooling was fabricated by traditional machining of the copper substrate, and H13 powder was deposited on the copper via the Laser Engineered Net Shape (LENSTM) process. The H13 deposition layer was then final machined by traditional methods. Two tooling components were designed and fabricated; a thermal fatigue test specimen, and a core for a commercial aluminum high pressure die casting tool. The bimetallic thermal fatigue specimen demonstrated promising performance during testing, and the test results were used to improve the design and LENS TM deposition methods for subsequent manufacture of the commercial core. Results of the thermal finite element analysis for the thermal fatigue test specimen indicate that it has the ability to lose heat to the internal water cooling passages, and to external spray cooling, significantly faster than a monolithic H13 thermal fatigue sample. The commercial core is currently in the final stages of fabrication, and will be evaluated in an actual production environment at Shiloh Die casting. In this research, the feasibility of designing and fabricating copper/H13 bimetallic die casting tooling via LENS TM processing, for the purpose of improving die casting process efficiency, is demonstrated.« less

  16. Economic impact analysis of an end-of-life programme for nursing home residents.

    PubMed

    Teo, W-S Kelvin; Raj, Anusha Govinda; Tan, Woan Shin; Ng, Charis Wei Ling; Heng, Bee Hoon; Leong, Ian Yi-Onn

    2014-05-01

    Due to limited end-of-life discussions and the absence of palliative care, hospitalisations are frequent at the end of life among nursing home residents in Singapore, resulting in high health-care costs. Our objective was to evaluate the economic impact of Project Care at the End-of-Life for Residents in homes for the Elderly (CARE) programme on nursing home residents compared to usual end-of-life care. DESIGN AND SETTINGS/PARTICIPANTS: Project CARE was introduced in seven nursing homes to provide advance care planning and palliative care for residents identified to be at risk of dying within 1 year. The cases consisted of nursing home residents enrolled in the Project CARE programme for at least 3 months. A historical group of nursing home residents not in any end-of-life care programme was chosen as the matched controls. Cost differences between the two groups were analysed over the last 3 months and final month of life. The final sample comprised 48 Project CARE cases and 197 controls. Compared to the controls, the cases were older with more comorbidities and higher nursing needs. After risk adjustment, Project CARE cases demonstrated per-resident cost savings of SGD$7129 (confidence interval: SGD$4544-SGD$9714) over the last 3 months of life and SGD$3703 (confidence interval: SGD$1848-SGD$5557) over the last month of life (US$1 = SGD$1.3). This study demonstrated substantial savings associated with an end-of-life programme. With a significant proportion of the population in Singapore requiring nursing home care in the near future, these results could assist policymakers and health-care providers in decision-making on allocation of health-care resources.

  17. Assisted Dying in Canada.

    PubMed

    Schuklenk, Udo

    This paper makes an affirmative ethical case in favour of the decriminalization of assisted dying in Canada. It then proceeds to defending the affirmative case against various slippery-slope arguments that are typically deployed by opponents of assisted dying. Finally, a recent case of questionable professional conduct by anti-euthanasia campaigners cum academics is flagged as a warning to all of us not to permit the quality of the professional debate to deteriorate unacceptably, despite the personal emotional investments involved on all sides of the debate.

  18. Heat damage-free laser-microjet cutting achieves highest die fracture strength

    NASA Astrophysics Data System (ADS)

    Perrottet, Delphine; Housh, Roy; Richerzhagen, Bernold; Manley, John

    2005-04-01

    Unlike conventional laser-based technologies, the water jet guided laser does not generate heat damage and contamination is also very low. The negligible heat-affected zone is one reason why die fracture strength is higher than with sawing. This paper first presents the water jet guided laser technology and then explains how it differs from conventional dry laser cutting. Finally, it presents the results obtained by three recent studies conducted to determine die fracture strength after Laser-Microjet cutting.

  19. Investigation of a Hybrid Wafer Scale Integration Technique that Mounts Discrete Integrated Circuit Die in a Silicon Substrate.

    DTIC Science & Technology

    1988-03-01

    Polyimides as Planarizing and Insulative Coatings 2-21 III. Experimental Procedure, Equipment, and Materials 3-1 Wet Orientation Dependent Etching Study 3...1 Die Bond Adhesives Study .3-7 Fabrication of Samples for Electrical Testing 3-21 Evaluation of the Final Samples 3-45 IV. Experimental Results and...Discussion .. 4-1 We :ientation Dependent Etching Study Results 4-1 Die Attach Adhesives Study Results 4-21 Fabrication of Samples for Electrical

  20. Influence of die geometry and material selection on the behavior of protective die covers in closed-die forging

    NASA Astrophysics Data System (ADS)

    Yu, Yingyan; Rosenstock, Dirk; Wolfgarten, Martin; Hirt, Gerhard

    2016-10-01

    Due to the fact that tooling costs make up to 30% of total costs of the final forged part, the tool life is always one main research topic in closed-die forging [1]. To improve the wear resistance of forging dies, many methods like nitriding and deposition of ceramic layers have been used. However, all these methods will lose its effect after a certain time, then tool repair or exchange is needed, which requires additional time and costs. A new method, which applies an inexpensive and changeable sheet metal on the forging die to protect it from abrasive wear, was firstly proposed in [2]. According to the first investigation, the die cover is effective for decreasing thermal and mechanical loads, but there are still several challenges to overcome in this concept, like wrinkling and thinning of the die cover. Therefore, an experimental study using different geometries and die cover materials is presented within this work. The results indicate the existence of feasible application cases of this concept, since conditions are found under which a die cover made of 22MnB5 still keeps its original shape even after 7 forging cycles.

  1. Development of Integrated Die Casting Process for Large Thin-Wall Magnesium Applications

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Carter, Jon T.; Wang, Gerry; Luo, Alan

    The purpose of this project was to develop a process and product which would utilize magnesium die casting and result in energy savings when compared to the baseline steel product. The specific product chosen was a side door inner panel for a mid-size car. The scope of the project included: re-design of major structural parts of the door, design and build of the tooling required to make the parts, making of parts, assembly of doors, and testing (both physical and simulation) of doors. Additional work was done on alloy development, vacuum die casting, and overcasting, all in order to improvemore » the performance of the doors and reduce cost. The project achieved the following objectives: 1. Demonstrated ability to design a large thin-wall magnesium die casting. 2. Demonstrated ability to manufacture a large thin-wall magnesium die casting in AM60 alloy. 3. Tested via simulations and/or physical tests the mechanical behavior and corrosion behavior of magnesium die castings and/or lightweight experimental automotive side doors which incorporate a large, thin-wall, powder coated, magnesium die casting. Under some load cases, the results revealed cracking of the casting, which can be addressed with re-design and better material models for CAE analysis. No corrosion of the magnesium panel was observed. 4. Using life cycle analysis models, compared the energy consumption and global warming potential of the lightweight door with those of a conventional steel door, both during manufacture and in service. Compared to a steel door, the lightweight door requires more energy to manufacture but less energy during operation (i.e., fuel consumption when driving vehicle). Similarly, compared to a steel door, the lightweight door has higher global warming potential (GWP) during manufacture, but lower GWP during operation. 5. Compared the conventional magnesium die casting process with the “super-vacuum” die casting process. Results achieved with cast tensile bars suggest some improvement in tensile properties with vacuum casting. Plant trials with large castings revealed cavity fill issues attributed to cooling and partial solidification of metal in the shot sleeve while waiting for vacuum to be established in the die cavity. 6. Developed age-hardenable Mg-based alloys as potential alternatives to the AM60 and AZ91 alloys typically used in automotive applications. Mg-7%Al-based alloys having Sn or Sn+Si additions exhibited significant age hardening, but more work is needed to demonstrate significant improvement in tensile properties. Corrosion behavior of these alloys is between those of AM60 and AZ91 alloys. 7. Evaluated the die casting of magnesium directly onto either steel or aluminum tubes as a potential process to make large lightweight subassemblies. Samples were free of gross defects, but additional work is needed to increase the interfacial shear strength. Overall, the project demonstrated that an automotive door-in-white design incorporating a die cast magnesium inner panel and a stamped aluminum outer panel can achieve approximately 50% mass reduction compared to the stamped steel baseline door-in-white. This leads to reduced energy consumption when driving the vehicle, which should more than offset the increased embedded energy of manufacture associated with the lighter metals. However, additional design work would be needed in order to meet the mechanical performance required of a door. Development of high-strength, high-ductility magnesium alloy castings would help make this technology more attractive for potential use in the side doors on automobiles. Also, increased use of recycled magnesium and aluminum would reduce the embedded energy and greenhouse gas emissions associated with the manufacture of this type of lightweight door. Commercialization planning of the type of lightweight door technology addressed in this project would be contingent upon the doors meeting all technical performance requirements of the car maker. The specific lightweight door developed in this project didn’t meet some of those requirements, but a preliminary business case study was conducted anyhow. This study considered the ratio of cost increase to mass decrease when the lightweight door is compared to a baseline steel door. The ratio was found to be in an acceptable range for some vehicle programs, especially if the number of such vehicles to be produced is equal to or slightly less than the estimated 250,000-shot life of the die set. This would allow for the investment in the dies to be spread across many parts and thereby help minimize the cost increase.« less

  2. CAD system of design and engineering provision of die forming of compressor blades for aircraft engines

    NASA Astrophysics Data System (ADS)

    Khaimovich, I. N.

    2017-10-01

    The articles provides the calculation algorithms for blank design and die forming fitting to produce the compressor blades for aircraft engines. The design system proposed in the article allows generating drafts of trimming and reducing dies automatically, leading to significant reduction of work preparation time. The detailed analysis of the blade structural elements features was carried out, the taken limitations and technological solutions allowed forming generalized algorithms of forming parting stamp face over the entire circuit of the engraving for different configurations of die forgings. The author worked out the algorithms and programs to calculate three dimensional point locations describing the configuration of die cavity. As a result the author obtained the generic mathematical model of final die block in the form of three-dimensional array of base points. This model is the base for creation of engineering documentation of technological equipment and means of its control.

  3. Highlighting the History of French Radio Astronomy. 7: The Genesis of the Institute of Astronomy at Millimeter Wavelengths (IRAM)

    NASA Astrophysics Data System (ADS)

    Encrenaz, Pierre; Gómez González, Jesús; Lequeux, James; Orchiston, Wayne

    2011-07-01

    Radio astronomy in France and in Germany started around 1950. France was then building interferometers and Germany large single dishes, so it was not unexpected that their first projects involving millimetre radio astronomy were respectively with an interferometer and a single dish. In this paper, we explain in detail how these two projects finally merged in 1979 with the formation of the Institute of Radio Astronomy at Millimetre Wavelengths (IRAM), after a long process with many ups and downs. We also describe how Spain started radio astronomy by joining IRAM. Presently, IRAM is the most powerful facility worldwide for millimetre radio astronomy. We wish to dedicate our paper to the memory of Émile-Jacques Blum (1923-2009), who played a major role in the construction of IRAM but died before he could participate in the writing of this paper. An interview made one month before his death was very useful in the preparation of this paper.

  4. Drama in Education and Self-Directed Learning for Adults

    ERIC Educational Resources Information Center

    Karavoltsou, Athina A.; O'Sullivan, Carmel

    2011-01-01

    Drama in Education (DIE), as an artistic and educational experience, is sufficiently evidenced in the literature as a dialogical, liberating practice of education. This article discusses a practitioner research project in a second chance adult education school in Greece, where the use of a DIE teaching and learning approach was explored in an…

  5. The new analysis method of PWQ in the DRAM pattern

    NASA Astrophysics Data System (ADS)

    Han, Daehan; Chang, Jinman; Kim, Taeheon; Lee, Kyusun; Kim, Yonghyeon; Kang, Jinyoung; Hong, Aeran; Choi, Bumjin; Lee, Joosung; Kim, Hyoung Jun; Lee, Kweonjae; Hong, Hyoungsun; Jin, Gyoyoung

    2016-03-01

    In a sub 2Xnm node process, the feedback of pattern weak points is more and more significant. Therefore, it is very important to extract the systemic defect in Double Patterning Technology(DPT), however, it is impossible to predict exact systemic defect at the recent photo simulation tool.[1] Therefore, the method of Process Window Qualification (PWQ) is very serious and essential these days. Conventional PWQ methods are die to die image comparison by using an e-beam or bright field machine. Results are evaluated by the person, who reviews the images, in some cases. However, conventional die to die comparison method has critical problem. If reference die and comparison die have same problem, such as both of dies have pattern problems, the issue patterns are not detected by current defect detecting approach. Aside from the inspection accuracy, reviewing the wafer requires much effort and time to justify the genuine issue patterns. Therefore, our company adopts die to data based matching PWQ method that is using NGR machine. The main features of the NGR are as follows. First, die to data based matching, second High speed, finally massive data were used for evaluation of pattern inspection.[2] Even though our die to data based matching PWQ method measures the mass data, our margin decision process is based on image shape. Therefore, it has some significant problems. First, because of the long analysis time, the developing period of new device is increased. Moreover, because of the limitation of resources, it may not examine the full chip area. Consequently, the result of PWQ weak points cannot represent the all the possible defects. Finally, since the PWQ margin is not decided by the mathematical value, to make the solid definition of killing defect is impossible. To overcome these problems, we introduce a statistical values base process window qualification method that increases the accuracy of process margin and reduces the review time. Therefore, it is possible to see the genuine margin of the critical pattern issue which we cannot see on our conventional PWQ inspection; hence we can enhance the accuracy of PWQ margin.

  6. Is the level of education associated with transitions between care settings in older adults near the end of life? A nationwide, retrospective cohort study.

    PubMed

    Kelfve, Susanne; Wastesson, Jonas; Fors, Stefan; Johnell, Kristina; Morin, Lucas

    2018-02-01

    End-of-life transitions between care settings can be burdensome for older adults and their relatives. To analyze the association between the level of education of older adults and their likelihood to experience care transitions during the final months before death. Nationwide, retrospective cohort study using register data. Older adults (⩾65 years) who died in Sweden in 2013 ( n = 75,722). Place of death was the primary outcome. Institutionalization and multiple hospital admissions during the final months of life were defined as secondary outcomes. The decedents' level of education (primary, secondary, or tertiary education) was considered as the main exposure. Multivariable analyses were stratified by living arrangement and adjusted for sex, age at time of death, illness trajectory, and number of chronic diseases. Among community-dwellers, older adults with tertiary education were more likely to die in hospitals than those with primary education (55.6% vs 49.9%; odds ratio (OR) = 1.21, 95% confidence interval (CI) = 1.14-1.28), but less likely to be institutionalized during the final month before death (OR = 0.83, 95% CI = 0.76-0.91). Decedents with higher education had greater odds of remaining hospitalized continuously during their final 2 weeks of life (OR = 1.12, 95% CI = 1.02-1.22). Among older adults living in nursing homes, we found no association between the decedents' level of education and their likelihood to be hospitalized or to die in hospitals. Compared with those who completed only primary education, individuals with higher educational attainment were more likely to live at home until the end of life, but also more likely to be hospitalized and die in hospitals.

  7. Sputtered protective coatings for die casting dies

    NASA Technical Reports Server (NTRS)

    Mirtich, M. J.; Nieh, C.-Y.; Wallace, J. F.

    1981-01-01

    Three experimental research designs investigating candidate materials and processes involved in protective die surface coating procedures by sputter deposition, using ion beam technologies, are discussed. Various pre-test results show that none of the coatings remained completely intact for 15,000 test cycles. The longest lifetime was observed for coatings such as tungsten, platinum, and molybdenum which reduced thermal fatigue, but exhibited oxidation and suppressed crack initiation only as long as the coating did not fracture. Final test results confirmed earlier findings and coatings with Pt and W proved to be the candidate materials to be used on a die surface to increase die life. In the W-coated specimens, which remained intact on the surface after thermal fatigue testing, no oxidation was found under the coating, although a few cracks formed on the surface where the coating broke down. Further research is planned.

  8. WA3 Room for death - international museum - visitors' preferences regarding the end of their life.

    PubMed

    Lindqvist, Olav; Tishelman, Carol

    2015-04-01

    Just as pain medications aim to relieve physical suffering, supportive surrounding for death and dying may facilitate well-being and comfort. However, little has been written of the experience of or preferences for settings for death and dying. We investigate preferences for and reflections about settings for end-of-life (EoL) in an international sample of museum visitors. Data derive from a project teaming artists and craftspeople together to create prototypes of space for difficult conversations in EoL settings. These prototypes were presented in a museum exhibition, "Room for Death", in Stockholm in 2012. As project consultants, we contributed a question to the public viewing the exhibition: "How would you like it to be around you when you are dying?" and analysed responses with a phenomenographic approach. Five-hundred twelve responses were obtained from visitors from 46 countries. Responses were categorised in the following inductively- derived categories of types of deaths: The "Familiar", "Larger-than life", "Lone", "Mediated" "Calm and peaceful", "Sensuous", "'Green'", and "Distanced" death. Responses could relate to one category or be composites uniting different categories in individual combinations. These data provide insight into different facets of contemporary reflections about death and dying. Despite the selective sample, the findings give reason to consider how underlying assumptions and care provision in established forms for EoL care may differ from people's preferences. This project can be seen as an example of innovative endeavours to promote public awareness of issues related to death and dying, within the framework of health-promoting palliative care. © 2015, Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

  9. Project THEORIA: New Media for Values Education.

    ERIC Educational Resources Information Center

    Covey, Preston

    1989-01-01

    Describes Project THEORIA, which was developed at Carnegie Mellon University to design interactive simulation environments for testing hypotheses and theories of the arts and human morals. Three projects in various stages of design and development are described: (1) "A Right to Die?; (2) "Art or Forgery?"; and (3) "Birth or…

  10. The rights of the dying child and the duties of healthcare providers: the "Trieste Charter".

    PubMed

    Benini, Franca; Vecchi, Roberta; Lazzarin, Pierina; Jankovic, Momcilo; Orsi, Luciano; Manfredini, Luca; Drigo, Paola; Sellaroli, Valentina; Gangemi, Michele; Spizzichino, Marco; Orzalesi, Marcello

    2017-01-21

    The death of a child is a devastating and tragic event for all those involved. This charter aims to help healthcare workers and people assisting terminally ill children to recognize some important rights of the child, with some related suggestions. We consider it important to have a trace of this process, based on the skillfulness of long-lasting experts. In September 2012, a group of professionals working with children affected by incurable illness in Italy launched a project to formulate the charter. Trieste is the city where the group of professionals first met to start the project. The first step was a detailed literature search on the topic, the second step was an extensive discussion among the professionals (writing committee) to prepare a first draft; later (third step) the draft was revised by 38 experts in different areas, including patient and family representatives, and lastly (fourth step) the final version of the charter was prepared. We developed a document containing 10 rights and corresponding duties that could be applied to any clinical situation or circumstances and used as a guide by professionals and families caring for children in the terminal stages of an illness. The Trieste Charter proposes fundamental rights for children who are approaching the end of their lives. The charter will have achieved its purpose when every person caring for a dying child is capable of staying near the child until the last moments of his or her life, prepared to accept his or her death, ensuring both respect and dignity.

  11. Dimensional control of die castings

    NASA Astrophysics Data System (ADS)

    Karve, Aniruddha Ajit

    The demand for net shape die castings, which require little or no machining, is steadily increasing. Stringent customer requirements are forcing die casters to deliver high quality castings in increasingly short lead times. Dimensional conformance to customer specifications is an inherent part of die casting quality. The dimensional attributes of a die casting are essentially dependent upon many factors--the quality of the die and the degree of control over the process variables being the two major sources of dimensional error in die castings. This study focused on investigating the nature and the causes of dimensional error in die castings. The two major components of dimensional error i.e., dimensional variability and die allowance were studied. The major effort of this study was to qualitatively and quantitatively study the effects of casting geometry and process variables on die casting dimensional variability and die allowance. This was accomplished by detailed dimensional data collection at production die casting sites. Robust feature characterization schemes were developed to describe complex casting geometry in quantitative terms. Empirical modeling was utilized to quantify the effects of the casting variables on dimensional variability and die allowance for die casting features. A number of casting geometry and process variables were found to affect dimensional variability in die castings. The dimensional variability was evaluated by comparisons with current published dimensional tolerance standards. The casting geometry was found to play a significant role in influencing the die allowance of the features measured. The predictive models developed for dimensional variability and die allowance were evaluated to test their effectiveness. Finally, the relative impact of all the components of dimensional error in die castings was put into perspective, and general guidelines for effective dimensional control in the die casting plant were laid out. The results of this study will contribute to enhancement of dimensional quality and lead time compression in the die casting industry, thus making it competitive with other net shape manufacturing processes.

  12. A study on die wear model of warm and hot forgings

    NASA Astrophysics Data System (ADS)

    Kang, J. H.; Park, I. W.; Jae, J. S.; Kang, S. S.

    1998-05-01

    Factors influencing service lives of tools in warm and hot forging processes are wear, mechanical fatigue, plastic deformation and thermal fatigue, etc. Wear is the predominant factor for tool failure among these. To predict tool life by wear, Archard's model where hardness is considered as constant or function of temperature is generally applied. Usually hardness of die is a function of not only temperature but operating time of die. To consider softening of die by repeated operation it is necessary to express hardness of die by a function of temperature and time. In this study wear coefficients were measured for various temperatures and heat treatment for H13 tool steel. Also by experiment of reheating of die, die softening curves were obtained. From experimental results, relationships between tempering parameters and hardness were established to investigate effects of hardness decrease by the effect of temperatures and time. Finally modified Archard's wear model in which hardness is considered to be a function of main tempering curve was proposed. And finite element analyses were conducted by adopting suggested wear model. By comparisons of simulations and real profiles of worn die, proposed wear model was verified.

  13. Development and evaluation of die materials for use in the growth of silicon ribbons by the inverted ribbon growth process, task 2. LSSA project

    NASA Technical Reports Server (NTRS)

    Duffy, M. T.; Berkman, S.; Moss, H. S.; Cullen, G. W.

    1978-01-01

    The results of emission spectroscopic analysis indicate that molten silicon can remain in contact with hot-pressed Si3N4 (99.2 percent theoretical density) for prolonged periods without attaining the impurity content level of the nitride. Although MgO was used as binder, Mg was not found present in the silicon sessile drop in quantities much above the level initially present in the silicon source material. Preliminary experiments with EFG-type dies coated with CVD Si3N4 or CVD SiOxNy indicate that capillary rise does not occur readily in these dies. The same was found to be true of hot-pressed and reaction-sintered Si3N4 obtained commercially. However, when dies were formed by depositing CVD layers on shaped silicon slabs, a column of molten silicon was maintained in each CVD die while being heated in contact with a crucible of molten silicon. Preliminary wetting of dies appears necessary for EFG growth. Several ribbon growth experiments were performed from V-shaped dies.

  14. Making Contact: The NAMES Project in Comparison to the Vietnam Memorial.

    ERIC Educational Resources Information Center

    Jensen, Marvin D.

    Several principles of gestalt therapy are applied in an analysis of the similarities between the Vietnam Veterans Memorial and The NAMES Project Quilt. The NAMES Project Quilt memorializes people who have died of Acquired Immune Deficiency Syndrome (AIDS). The creators of the two memorials engaged in the initial searches for "whole"…

  15. Precision technique for trimming dies using a magnification device.

    PubMed

    Beck, D B

    1980-05-01

    This article described a technique for trimming a die under magnification. However, the microscope is also useful for checking (1) margins of wax patterns for completeness, (2) the internal surfaces of castings for imperfections, bubbles, or retained investment particles which could prevent proper seating of the castings on the dies, (3) for cracks or contamination in dental porcelain as well as porcelain flash on margins; and (4) precision attachment operation after casting or soldering procedures. Attention to detail in these laboratory procedures greatly improves the final fit of dental castings and saves subsequent chairside adjustments and remakes.

  16. Care seeking for fatal illness episodes in Neonates: a population-based study in rural Bangladesh

    PubMed Central

    2011-01-01

    Background Poor neonatal health is a major contributor to under-five mortality in developing countries. A major constraint to effective neonatal survival programme has been the lack of population level data in developing countries. This study investigated the consultation patterns of caregivers during neonatal fatal illness episodes in the rural Matlab sub-district of eastern Bangladesh. Methods Neonatal deaths were identified through a population-based demographic surveillance system in Matlab ICDDR,B maternal and child health (MCH) project area and an adjoining government service area. Trained project staff administered a structured questionnaire on care seeking to mothers at home who had experienced a neonatal death. Univariate, bivariate and binary multivariate logistic regressions were performed to describe care seeking during the fatal illness episode. Results Of the 365 deaths recorded during 2003 and 2004, 84% died in the early (0-7 days) neonatal period, with the remaining deaths occurring over the subsequent 8 to 28 days. The first resort of care by parents was a qualified doctor or paramedic in 37% of cases, followed by traditional and unqualified health care providers in 25%, while 38% sought no care. Thus, almost two thirds (63%) of neonates who died received only traditional and unqualified care or no care at all during their final illness episode. About 22% sought care from more than one provider, including 6% from 3 or more providers. Such plurality in care seeking was more likely among male infants, in the late neonatal period, and in the MCH project area. Conclusions The high proportion of neonatal deaths that had received traditional care or no medical care in a rural area of Bangladesh highlights the need to develop community awareness about prompt medical care seeking for neonatal illnesses and to improve access to effective health care. Integration of traditional care providers into mainstream health programs should also be considered. PMID:21999253

  17. A Low Power SOC Architecture for the V2.0+EDR Bluetooth Using a Unified Verification Platform

    NASA Astrophysics Data System (ADS)

    Kim, Jeonghun; Kim, Suki; Baek, Kwang-Hyun

    This paper presents a low-power System on Chip (SOC) architecture for the v2.0+EDR (Enhanced Data Rate) Bluetooth and its applications. Our design includes a link controller, modem, RF transceiver, Sub-Band Codec (SBC), Expanded Instruction Set Computer (ESIC) processor, and peripherals. To decrease power consumption of the proposed SOC, we reduce data transfer using a dual-port memory, including a power management unit, and a clock gated approach. We also address some of issues and benefits of reusable and unified environment on a centralized data structure and SOC verification platform. This includes flexibility in meeting the final requirements using technology-independent tools wherever possible in various processes and for projects. The other aims of this work are to minimize design efforts by avoiding the same work done twice by different people and to reuse the similar environment and platform for different projects. This chip occupies a die size of 30mm2 in 0.18µm CMOS, and the worst-case current of the total chip is 54mA.

  18. TUNGSTEN BASE ALLOYS

    DOEpatents

    Schell, D.H.; Sheinberg, H.

    1959-12-15

    A high-density quaternary tungsten-base alloy having high mechanical strength and good machinability composed of about 2 wt.% Ni, 3 wt.% Cu, 5 wt.% Pb, and 90wt.% W is described. This alloy can be formed by the powder metallurgy technique of hot pressing in a graphite die without causing a reaction between charge and the die and without formation of a carbide case on the final compact, thereby enabling re-use of the graphite die. The alloy is formable at hot- pressing temperatures of from about 1200 to about 1350 deg C. In addition, there is little component shrinkage, thereby eliminating the necessity of subsequent extensive surface machining.

  19. [Dying with cancer: Hollywood lessons].

    PubMed

    Niemeyer, Fernanda; Kruse, Maria Henriqueta Luce

    2013-12-01

    The study attempts to understand how dying from cancer is portrayed by five movies produced in Hollywood between 1993 and 2006. Based on the cultural studies and their post-structuralism version and supported by the notions of discourse and subjectivity, as proposed by philosopher Michel Foucault, we suggest one of the possible readings of the movie picture corpus. We assess how the movie picture discourse acts as a cultural pedagogy that produces ways of seeing dying with cancer: immortalizing the healthy body image, silencing death, taking care of the dead body and, finally, accepting death. Our proposal is intended to stimulate reflections that may contribute to care and education in nursing.

  20. Development and Demonstration of Adanced Tooling Alloys for Molds and Dies

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kevin M. McHugh; Enrique J. Lavernia

    2006-01-01

    This report summarizes research results in the project Development and Demonstration of Advanced Tooling Alloys for Molds and Dies. Molds, dies and related tooling are used to manufacture most of the plastic and metal products we use every day. Conventional fabrication of molds and dies involves a multiplicity of machining, benching and heat treatment unit operations. This approach is very expensive and time consuming. Rapid Solidifcation Process (RSP) Tooling is a spray-forming technology tailored for producing molds and dies. The appraoch combines rapid solidifcation processing and net-shape materials processing in a single step. An atomized spray of a tool-forming alloy,more » typically a tool steel, is deposited onto an easy-to-form tool pattern to replicate the pattern's shape and surface features. By so doing, the approach eliminates many machining operations in conventional mold making, significantly reducing cost, lead time and energy. Moreover, rapid solidification creates unique microstructural features by suppressing carbide precipitation and growth, and creating metastable phases. This can result in unique material properties following heat treatment. Spray-formed and aged tool steel dies have exhibited extended life compared to conventional dies in many forming operations such as forging, extrusion and die casting. RSP Tooling technolocy was commercialized with the formation of RSP Tooling, LLC in Solon, Oh.« less

  1. [Dying and death in societal transformation].

    PubMed

    Heller, Andreas; Wegleitner, Klaus

    2017-01-01

    Dying and death in modern societies are subject to profound social, professional and cultural-religious changes. Secularization and a stronger differentiation of societies have led to a change in the way humans handle the dying process. Normatively ritualized collective behaviour has been replaced by an individual, subjectivized approach. In late modern societies there are many different views of what "successful" or "good" dying means.In the article this change is described by the following seven theses: 1. We live longer and we die longer. 2. We no longer die suddenly and unexpectedly but slowly and foreseeably. 3. Even though our biological life on earth has become longer, our life has been shortened by the loss of eternity. 4. We no longer die on the stage of ritualized relationships with our family and neighbours but behind the curtains of organizations. 5. We live and die in a society of organizations and have to get organized for the final phase of our life. 6. Living and dying are no large, state-owned enterprises but small, private enterprises. 7. The hospice movement as well as palliative medicine have created public awareness, made dying a matter of discussion and offered a new set of options.In late modernism end-of-life care requires new approaches based on individual and shared responsibility as well as cooperation between professional institutions and community-based voluntary care.A change towards community care is visible. Thus "dying" is a topic in the discussion about the future of public health and societal solidarity.

  2. Room for Death--International museum-visitors' preferences regarding the end of their life.

    PubMed

    Lindqvist, Olav; Tishelman, Carol

    2015-08-01

    Just as pain medications aim to relieve physical suffering, supportive surrounding for death and dying may facilitate well-being and comfort. However, little has been written of the experience of or preferences for the surroundings in which death and dying take place. In this study, we aim to complement our research from perspectives of patients, family members and staff, with perspectives from an international sample of the general public. Data derives from a project teaming artists and craftspeople together to create prototypes of space for difficult conversations in end-of-life (EoL) settings. These prototypes were presented in a museum exhibition, "Room for Death", in Stockholm in 2012. As project consultants, palliative care researchers contributed a question to the public viewing the exhibition, to explore their reflections: "How would you like it to be around you when you are dying?" Five-hundred and twelve responses were obtained from visitors from 46 countries. While preliminary analysis pointed to many similarities in responses across countries, continued analysis with a phenomenographic approach allowed us to distinguish different foci related to how preferences for surroundings for EoL were conceptualized. Responses were categorized in the following inductively-derived categories: The familiar death, The 'larger-than life' death, The lone death, The mediated death, The calm and peaceful death, The sensuous death, The 'green' death, and The distanced death. The responses could relate to a single category or be composites uniting different categories in individual combinations, and provide insight into different facets of contemporary reflections about death and dying. Despite the selective sample, these data give reason to consider how underlying assumptions and care provision in established forms for end-of-life care may differ from people's preferences. This project can be seen as an example of innovative endeavors to promote public awareness of issues related to death and dying, within the framework of health-promoting palliative care. Copyright © 2015 Elsevier Ltd. All rights reserved.

  3. Vital signs: melanoma incidence and mortality trends and projections - United States, 1982-2030.

    PubMed

    Guy, Gery P; Thomas, Cheryll C; Thompson, Trevor; Watson, Meg; Massetti, Greta M; Richardson, Lisa C

    2015-06-05

    Melanoma incidence rates have continued to increase in the United States, and risk behaviors remain high. Melanoma is responsible for the most skin cancer deaths, with about 9,000 persons dying from it each year. CDC analyzed current (2011) melanoma incidence and mortality data, and projected melanoma incidence, mortality, and the cost of treating newly diagnosed melanomas through 2030. Finally, CDC estimated the potential melanoma cases and costs averted through 2030 if a comprehensive skin cancer prevention program was implemented in the United States. In 2011, the melanoma incidence rate was 19.7 per 100,000, and the death rate was 2.7 per 100,000. Incidence rates are projected to increase for white males and females through 2019. Death rates are projected to remain stable. The annual cost of treating newly diagnosed melanomas was estimated to increase from $457 million in 2011 to $1.6 billion in 2030. Implementation of a comprehensive skin cancer prevention program was estimated to avert 230,000 melanoma cases and $2.7 billion in initial year treatment costs from 2020 through 2030. If additional prevention efforts are not undertaken, the number of melanoma cases is projected to increase over the next 15 years, with accompanying increases in health care costs. Much of this morbidity, mortality, and health care cost can be prevented. Substantial reductions in melanoma incidence, mortality, and cost can be achieved if evidence-based comprehensive interventions that reduce ultraviolet (UV) radiation exposure and increase sun protection are fully implemented and sustained.

  4. 77 FR 42694 - Helena National Forest, Montana, Telegraph Vegetation Project

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-20

    ... slashing generally small diameter trees followed by prescribed burning within the Jericho Mountain... dead and dying trees, promoting desirable regeneration, reducing fuels and the risk of wildfire, and... for Action Wide-scale tree mortality has occurred throughout the project area due to the mountain pine...

  5. Rapid tooling for functional prototyping of metal mold processes. CRADA final report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zacharia, T.; Ludtka, G.M.; Bjerke, M.A.

    1997-12-01

    The overall scope of this endeavor was to develop an integrated computer system, running on a network of heterogeneous computers, that would allow the rapid development of tool designs, and then use process models to determine whether the initial tooling would have characteristics which produce the prototype parts. The major thrust of this program for ORNL was the definition of the requirements for the development of the integrated die design system with the functional purpose to link part design, tool design, and component fabrication through a seamless software environment. The principal product would be a system control program that wouldmore » coordinate the various application programs and implement the data transfer so that any networked workstation would be useable. The overall system control architecture was to be required to easily facilitate any changes, upgrades, or replacements of the model from either the manufacturing end or the design criteria standpoint. The initial design of such a program is described in the section labeled ``Control Program Design``. A critical aspect of this research was the design of the system flow chart showing the exact system components and the data to be transferred. All of the major system components would have been configured to ensure data file compatibility and transferability across the Internet. The intent was to use commercially available packages to model the various manufacturing processes for creating the die and die inserts in addition to modeling the processes for which these parts were to be used. In order to meet all of these requirements, investigative research was conducted to determine the system flow features and software components within the various organizations contributing to this project. This research is summarized.« less

  6. Mille modis morimur: We die in a thousand ways.

    PubMed

    Banfalvi, Gaspar

    2017-02-01

    Dying cells subjected to apoptotic programs are engulfed by neighboring cells or by professional phagocytes, without inflammation or immunological reactions in the tissue where apoptosis takes place. Apoptotic cells release danger-associated project signals to their neighbours, through different molecular patterns, stimulate antigen production and immune responses. Microenvironmental effects with several functional consequences indicate that cell death is a complex process and may take place in several ways. This idea is expressed by the title of the Special Issue and by the title of the guest editorial "Mille modis morimur" meaning that not only multicellular organisms, but also single cells may die in a thousand ways. This idea is demonstrated by the papers serving as examples for cell death. Apoptosis was induced by clary sage oil in Candida cells. Heavy metal (Gd) induced cell motility and apoptosis was found in mammalian cells. RNA oxidation enhanced the reversion frequency of apoptosis in yeast mutants. The frequency of apoptotic micronucleus formation increased in a concentration-dependent manner by methotrexate. The antioxidant coenzyme Q10 protected renal proximal tubule cells against nicotine-induced apoptosis. The synergy of 2-deoxy-D-glucose combined with berberine induced lysosome/autophagy. The mitochondrial apoptotic pathway could be regulated by glucocorticoid receptor in collaboration with Bcl-2 family proteins in developing T cells. Cylindrospermopsin induced biochemical changes led to apoptosis in plants. Mechanisms of stress seriously impacted the risk of apoptosis. Transcriptional control of apoptotic cell clearance was achieved by macrophage nuclear receptors. Finally, the clinical aspects of apoptosis-induced lymphopenia were reviewed in sepsis and other severe injuries. These examples not only support the view of many ways of cell death, but predict further potential ways to induce or reduce the risk of cell death.

  7. Optimization of Surface Roughness and Wall Thickness in Dieless Incremental Forming Of Aluminum Sheet Using Taguchi

    NASA Astrophysics Data System (ADS)

    Hamedon, Zamzuri; Kuang, Shea Cheng; Jaafar, Hasnulhadi; Azhari, Azmir

    2018-03-01

    Incremental sheet forming is a versatile sheet metal forming process where a sheet metal is formed into its final shape by a series of localized deformation without a specialised die. However, it still has many shortcomings that need to be overcome such as geometric accuracy, surface roughness, formability, forming speed, and so on. This project focus on minimising the surface roughness of aluminium sheet and improving its thickness uniformity in incremental sheet forming via optimisation of wall angle, feed rate, and step size. Besides, the effect of wall angle, feed rate, and step size to the surface roughness and thickness uniformity of aluminium sheet was investigated in this project. From the results, it was observed that surface roughness and thickness uniformity were inversely varied due to the formation of surface waviness. Increase in feed rate and decrease in step size will produce a lower surface roughness, while uniform thickness reduction was obtained by reducing the wall angle and step size. By using Taguchi analysis, the optimum parameters for minimum surface roughness and uniform thickness reduction of aluminium sheet were determined. The finding of this project helps to reduce the time in optimising the surface roughness and thickness uniformity in incremental sheet forming.

  8. Development and Evaluation of Die Materials for Use in the Growth of Silicon Ribbons by the Inverted Ribbon Growth Process. Task 2: LSSA Project

    NASA Technical Reports Server (NTRS)

    Duffy, M. T.; Berkman, S.; Moss, H. I.; Cullen, G. W.

    1978-01-01

    Several ribbon growth experiments were performed from V-shaped dies coated with CVD Si3N4. The most significant result was the ability to perform five consecutive growth runs from the same die without mechanical degradation of the die through temperature cycling. The die was made from vitreous carbon coated with CVD Si3N4. Silicon oxynitride, Si2N2O, was examined with respect to thermal stability in contact with molten silicon. The results of X-ray analysis indicate that this material is converted to both alpha - and beta-Si3N4 in the presence of molten silicon. Experiments on the stability of CVD SiOxNy shoe that this material can be maintained in contact with molten silicon (sessile drop test) for greater than 30 h at 1450 C without total decompositon. These layers are converted mainly to beta-Si3N4.

  9. Evaluating the Tensile Properties of Aluminum Foundry Alloys through Reference Castings-A Review.

    PubMed

    Anilchandra, A R; Arnberg, Lars; Bonollo, Franco; Fiorese, Elena; Timelli, Giulio

    2017-08-30

    The tensile properties of an alloy can be exploited if detrimental defects and imperfections of the casting are minimized and the microstructural characteristics are optimized through several strategies that involve die design, process management and metal treatments. This paper presents an analysis and comparison of the salient characteristics of the reference dies proposed in the literature, both in the field of pressure and gravity die-casting. The specimens produced with these reference dies, called separately poured specimens, are effective tools for the evaluation and comparison of the tensile and physical behaviors of Al-Si casting alloys. Some of the findings of the present paper have been recently developed in the frame of the European StaCast project whose results are complemented here with some more recent outcomes and a comprehensive analysis and discussion.

  10. Evaluating the Tensile Properties of Aluminum Foundry Alloys through Reference Castings—A Review

    PubMed Central

    Anilchandra, A.R.; Arnberg, Lars; Bonollo, Franco; Fiorese, Elena

    2017-01-01

    The tensile properties of an alloy can be exploited if detrimental defects and imperfections of the casting are minimized and the microstructural characteristics are optimized through several strategies that involve die design, process management and metal treatments. This paper presents an analysis and comparison of the salient characteristics of the reference dies proposed in the literature, both in the field of pressure and gravity die-casting. The specimens produced with these reference dies, called separately poured specimens, are effective tools for the evaluation and comparison of the tensile and physical behaviors of Al-Si casting alloys. Some of the findings of the present paper have been recently developed in the frame of the European StaCast project whose results are complemented here with some more recent outcomes and a comprehensive analysis and discussion. PMID:28867796

  11. Dying with motor neurone disease, what can we learn from family caregivers?

    PubMed Central

    Ray, Robin A.; Brown, Janice; Street, Annette F.

    2012-01-01

    Abstract Background  Increasingly, people with neurodegenerative illness are cared for at home until close to death. Yet, discussing the reality of dying remains a social taboo. Objective  To examine the ways, family caregivers of people living with motor neurone disease (MND) experienced the dying of their relative and to identify how health practitioners can better prepare families for end‐of‐life care. Design  Secondary analysis was undertaken on data sets generated from two longitudinal qualitative studies employing similar data collection and analysis methods. Combining data sets increased participant numbers in a low incidence disease group. Setting and participants  Primary studies were undertaken with family caregivers in England and Australia. Interview and observational data were collected mostly in home. Participants who discussed dying and death formed the sample for secondary analysis. Results  Combined data revealed four major themes: planning for end of life, unexpected dying, dignity in the dying body and positive end to MND. Despite short survival predictions, discussions among family members about dying were often sporadic and linked to loss of hope. Effective planning for death assisted caregivers to manage the final degenerative processes of dying. When plans were not effectively communicated or enacted, capacity to preserve personhood was reduced. Discussion and Conclusion  Returning death and dying to social discourse will raise the level of community awareness and normalize conversations about end‐of‐life care. Strategies for on‐going, effective communication that facilitates advance care planning among patients, their families and practitioners are essential to improve dying and death for people with MND and their family caregivers. PMID:22512686

  12. An investigation on die crack detection using Temperature Sensitive Parameter for high speed LED mass production

    NASA Astrophysics Data System (ADS)

    Annaniah, Luruthudass; Devarajan, Mutharasu; San, Teoh Kok

    To ensure the highest quality & long-term reliability of LED components it is necessary to examine LED dice that have sustained mechanical damage during the manufacturing process. This paper has demonstrated that detection of die crack in mass manufactured LEDs can be achieved by measuring Temperature Sensitive Parameters (TSPs) during final testing. A newly-designed apparatus and microcontroller was used for this investigation in order to achieve the millisecond switching time needed for detecting thermal transient effects and at the same time meet the expected speed for mass manufacturing. Evaluations conducted at lab scale shows that thermal transient behaviour of cracked die is significantly different than that of an undamaged die. Having an established test limits to differentiate cracked dice, large volume tests in a production environment were used to confirm the effectiveness of this test method. Failure Bin Analysis (FBA) of this high volume experiment confirmed that all the cracked die LEDs were detected and the undamaged LEDs passed this test without over-rejection. The work verifies that tests based on TSP are effective in identifying die cracks and it is believed that the method could be extended to other types of rejects that have thermal transient signatures such as die delamination.

  13. Resource use during the last 6 months of life among COPD patients: a population level study.

    PubMed

    Faes, Kristof; Cohen, Joachim; Annemans, Lieven

    2018-06-11

    Chronic obstructive pulmonary disease (COPD) patients often have several comorbidities, such as cardiovascular diseases (CVD) or lung cancer (LC), which might influence resource use in the final months of life. However, no previous studies documented resource use in end-of-life COPD patients at a population level, thereby differentiating whether COPD patients die of their COPD, CVD or LC. To describe end-of-life resource use in people diagnosed with COPD and compare this resource use between those dying of COPD, CVD and LC. We performed a full-population retrospective analysis of all Belgian decedents. Those who died of COPD were selected based on the primary cause of death. Those who died with COPD but with CVD or LC as primary cause of death were identified based on a validated algorithm expanded with COPD as intermediate or associated. Resource use among 13.086 patients dying of or with COPD was studied. Those who died of COPD received less opioids, sedatives and morphine; used less palliative care services; and received more invasive and non-invasive ventilation as compared to the other 2 groups. Those who died of LC had more specialist contacts, hospital admissions and medical imaging as compared to those who died of COPD or CVD. Those who died of CVD used less palliative care services when compared to those who died of LC and had a comparable use of hospital, ICU, home care, opioids, sedatives and morphine as those who died of COPD. The presence of lung cancer and cardiovascular diseases influences resource use in COPD patients at life's end. We recommend that future research on end-of-life care in COPD systematically accounts for specific comorbidities. Copyright © 2018 American Academy of Hospice and Palliative Medicine. Published by Elsevier Inc. All rights reserved.

  14. Meteor Beliefs Project: Meteoric imagery in SF, Part II - H. P. Lovecraft's The Colour Out Of Space

    NASA Astrophysics Data System (ADS)

    McBeath, Alastair; Gheorghe, Andrei Dorian

    2005-12-01

    A brief biography of American horror-fiction writer H. P. Lovecraft (1890-1937) precedes details from his story `The Colour Out Of Space', concerning a deadly life-form brought to Earth in a meteorite. This allows a comparison with details from the 1965 film derived from this tale, `Die, Monster, Die!', featuring the great horror actor Boris Karloff in one of his last, best roles.

  15. 38 CFR 11.116 - Death of veteran before final settlement.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 1 2014-07-01 2014-07-01 false Death of veteran before... Death of veteran before final settlement. If the veteran dies after making application under the... death occurs after the application is filed but before payment is received under this Act, or if the...

  16. 38 CFR 11.116 - Death of veteran before final settlement.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 1 2013-07-01 2013-07-01 false Death of veteran before... Death of veteran before final settlement. If the veteran dies after making application under the... death occurs after the application is filed but before payment is received under this Act, or if the...

  17. 38 CFR 11.116 - Death of veteran before final settlement.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 1 2012-07-01 2012-07-01 false Death of veteran before... Death of veteran before final settlement. If the veteran dies after making application under the... death occurs after the application is filed but before payment is received under this Act, or if the...

  18. Improving the automated optimization of profile extrusion dies by applying appropriate optimization areas and strategies

    NASA Astrophysics Data System (ADS)

    Hopmann, Ch.; Windeck, C.; Kurth, K.; Behr, M.; Siegbert, R.; Elgeti, S.

    2014-05-01

    The rheological design of profile extrusion dies is one of the most challenging tasks in die design. As no analytical solution is available, the quality and the development time for a new design highly depend on the empirical knowledge of the die manufacturer. Usually, prior to start production several time-consuming, iterative running-in trials need to be performed to check the profile accuracy and the die geometry is reworked. An alternative are numerical flow simulations. These simulations enable to calculate the melt flow through a die so that the quality of the flow distribution can be analyzed. The objective of a current research project is to improve the automated optimization of profile extrusion dies. Special emphasis is put on choosing a convenient starting geometry and parameterization, which enable for possible deformations. In this work, three commonly used design features are examined with regard to their influence on the optimization results. Based on the results, a strategy is derived to select the most relevant areas of the flow channels for the optimization. For these characteristic areas recommendations are given concerning an efficient parameterization setup that still enables adequate deformations of the flow channel geometry. Exemplarily, this approach is applied to a L-shaped profile with different wall thicknesses. The die is optimized automatically and simulation results are qualitatively compared with experimental results. Furthermore, the strategy is applied to a complex extrusion die of a floor skirting profile to prove the universal adaptability.

  19. Wear Improvement of Tools in the Cold Forging Process for Long Hex Flange Nuts.

    PubMed

    Hsia, Shao-Yi; Shih, Po-Yueh

    2015-09-25

    Cold forging has played a critical role in fasteners and has been widely used in automotive production, manufacturing, aviation and 3C (Computer, Communication, and Consumer electronics). Despite its extensive use in fastener forming and die design, operator experience and trial and error make it subjective and unreliable owing to the difficulty of controlling the development schedule. This study used finite element analysis to establish and simulate wear in automotive repair fastener manufacturing dies based on actual process conditions. The places on a die that wore most quickly were forecast, with the stress levels obtained being substituted into the Archard equation to calculate die wear. A 19.87% improvement in wear optimization occurred by applying the Taguchi quality method to the new design. Additionally, a comparison of actual manufacturing data to simulations revealed a nut forging size error within 2%, thereby demonstrating the accuracy of this theoretical analysis. Finally, SEM micrographs of the worn surfaces on the upper punch indicate that the primary wear mechanism on the cold forging die for long hex flange nuts was adhesive wear. The results can simplify the development schedule, reduce the number of trials and further enhance production quality and die life.

  20. Wear Improvement of Tools in the Cold Forging Process for Long Hex Flange Nuts

    PubMed Central

    Hsia, Shao-Yi; Shih, Po-Yueh

    2015-01-01

    Cold forging has played a critical role in fasteners and has been widely used in automotive production, manufacturing, aviation and 3C (Computer, Communication, and Consumer electronics). Despite its extensive use in fastener forming and die design, operator experience and trial and error make it subjective and unreliable owing to the difficulty of controlling the development schedule. This study used finite element analysis to establish and simulate wear in automotive repair fastener manufacturing dies based on actual process conditions. The places on a die that wore most quickly were forecast, with the stress levels obtained being substituted into the Archard equation to calculate die wear. A 19.87% improvement in wear optimization occurred by applying the Taguchi quality method to the new design. Additionally, a comparison of actual manufacturing data to simulations revealed a nut forging size error within 2%, thereby demonstrating the accuracy of this theoretical analysis. Finally, SEM micrographs of the worn surfaces on the upper punch indicate that the primary wear mechanism on the cold forging die for long hex flange nuts was adhesive wear. The results can simplify the development schedule, reduce the number of trials and further enhance production quality and die life. PMID:28793589

  1. Wirkungen biogener Amine auf die Erregungs-Sekretions-Kopplung in der Speicheldrüse von Periplaneta americana (L.)

    NASA Astrophysics Data System (ADS)

    Rietdorf, Katja

    2003-07-01

    In der vorliegenden Arbeit habe ich wichtige Teilmechanismen der Erregungs-Sekretionskopplung in der Speicheldrüse der Schabe Periplaneta americana (L.) untersucht. Die Speicheldrüse ist von dopaminergen und serotonergen Fasern innerviert (Baumann et al., 2002). Beide Transmitter stimulieren eine unterschiedliche Reaktion der Drüse: Dopamin (DA) stimuliert die P-Zellen der Acini und die Ausführgangzellen, während Serotonin (5-HT) die P- und C-Zellen der Acini stimuliert, nicht jedoch die Ausführgangzellen. Der Endspeichel ist nach einer DA-Stimulierung proteinfrei. Dagegen enthält er nach einer 5-HT-Stimulierung Proteine, die von den C-Zellen sezerniert werden (Just & Walz, 1996). Im ersten Teil meiner Arbeit habe ich mittels Kapillarelektrophoretischer Analyse (CE-Analyse) die Elektrolytkonzentrationen im Endspeichel untersucht sowie die Raten der Flüssigkeitssekretion gemessen. Damit wollte ich klären, welche Transporter an der Sekretion des Primärspeichels und an dessen Modifikation beteiligt sind. Ausserdem wollte ich die Rolle der transportaktiven Epithelzellen der Ausführgänge für die Modifikation des Primärspeichels untersuchen. Dafür habe ich einen Vergleich der Elektrolytkonzentrationen im DA- und 5-HT-stimulierten Endspeichel durchgeführt. Der Elektrolytgehalt des DA- und 5-HT-stimulierten Endspeichels unterscheidet sich nicht signifikant voneinander. Er ist nach beiden Stimulierungen hypoosmotisch zum verwendeten Ringer. Die Ausführgangzellen werden durch DA stimuliert und modifizieren den Primärspeichel durch eine netto-Ionenreabsorption. Meine Versuche zeigen jedoch, dass auch die während einer 5-HT-Stimulierung der Drüse unstimulierten Ausführgangzellen den Primärspeichel modifizieren. In einer nachfolgenden Versuchsreihe habe ich den Einfluss von Ouabain, einem Hemmstoff der Na+-K+-ATPase, und Bumetanid, einem Hemmstoff des NKCC, auf die Raten der Flüssigkeitssekretion sowie den Elektrolytgehalt des Endspeichels untersucht. Ich habe gefunden, dass die Aktivität der Na+-K+-ATPase wichtig für die Modifikation des DA-stimulierten Primärspeichels ist. Im Gegensatz dazu ist sie für die Modifikation des 5-HT-stimulierten Primärspeichels nicht von Bedeutung. Bezüglich der Flüssigkeitssekretion habe ich keinen Einfluss der Na+-K+-ATPase-Aktivität auf die DA-stimulierten Sekretionsraten gefunden, dagegen ist die 5-HT-stimulierte Sekretionsrate in Anwesenheit von Ouabain gesteigert. Die Aktivität des NKCC ist für beide sekretorische Prozesse, die Ionen- und die Flüssigkeitssekretion, wichtig. Eine Hemmung des NKCC bewirkt eine signifikante Verringerung der Raten der Flüssigkeitssekretion nach DA- und 5-HT-Stimulierung sowie in beiden Fällen einen signifikanten Abfall der Ionenkonzentrationen im Endspeichel. Im zweiten Teil meiner Arbeit habe ich versucht, Änderungen der intrazellulären Ionenkonzentrationen in den Acinuszellen während einer DA- oder 5-HT-Stimulierung zu messen. Diese Experimente sollten mit der Methode des "ratiometric imaging" durchgeführt werden. Messungen mit dem Ca2+-sensitiven Fluoreszenzfarbstoff Fura-2 zeigten keinen globalen Anstieg in der intrazellulären Ca2+-Konzentration der P-Zellen. Aufgrund von Problemen mit einer schlechten Beladung der Zellen, einer starken und sich während der Stimulierung ändernden Autofluoreszenz der Zellen sowie Änderungen im Zellvolumen wurden keine Messungen mit Na+- und K+-sensitiven Fluoreszenzfarbstoffen durchgeführt. Im dritten Teil dieser Arbeit habe ich die intrazellulären Signalwege untersucht, die zwischen einer 5-HT-Stimulierung der Drüse und der Proteinsekretion vermitteln. Dazu wurde der Proteingehalt im Endspeichel biochemisch mittels eines modifizierten Bradford Assay gemessen. Eine erstellte Dosis-Wirkungskurve zeigt, dass die Rate der Proteinsekretion von der zur Stimulierung verwendeten 5-HT-Konzentration abhängt. In einer Serie von Experimenten habe ich die intrazellulären Konzentrationen von Ca2+, cAMP und / oder cGMP erhöht und anschließend den Proteingehalt im Endspeichel gemessen. Ein Anstieg der intrazellulären Ca2+-Konzentration aktiviert nur eine geringe Rate der Proteinsekretion. Dagegen kann die Steigerung der intrazellulären cAMP-Konzentration eine stärkere Proteinsekretion aktivieren, die sich nicht signifikant von der nach 5-HT-Stimulierung unterscheidet. Die cAMP-stimulierte Proteinsekretion kann durch gleichzeitige Erhöhung der intrazellulären Ca2+-Konzentration weiter gesteigert werden. Dagegen aktivierte eine Erhöhung der intrazellulären cGMP-Konzentration die Proteinsekretion nicht. Aufgrund dieser Ergebnisse postuliere ich die Existenz eines die Adenylatcyclase aktivierenden 5-HT-Rezeptors in der Basolateralmembran der C-Zellen. The aim of this PhD-work was to investigate major mechanisms of excitation-secretion coupling in the salivary gland of the cockroach Periplaneta americana (L.). This salivary gland is innervated by dopaminergic and serotonergic fibres (Baumann et al., 2002). The two transmitters stimulate different processes in the gland: Dopamine (DA) stimulates the p-cells of the acini and the salivary duct cells, whereas 5-HT (serotonin) activates the p- and the c-cells of the acini, but not the salivary duct cells. Final saliva is completely protein-free after dopamine stimulation. It contains proteins, which are secreted by the c-cells of the acini, after a 5-HT-stimulation (Just & Walz, 1996). In the first part of my work I measured the electrolytic composition of the final saliva by capillary electrophoretic analysis and measured the rates of fluid secretion, in order to answer the following questions: 1.) Which transporters affect the production of primary saliva and its modification? 2.) What is the function of the transport-active salivary duct cells for the modification of the primary saliva? Electrolytic composition of the DA- and 5-HT-stimulated final saliva is not significantly different from each other, and is hypoosmotic to the Ringer used. Salivary duct cells are stimulated by DA and modify the primary saliva by a netto ion-reabsorption. My experiments also show that the duct cells, which are unstimulated during a 5-HT-stimulation of the gland, modify the primary saliva. In the next series of experiments I investigated the effects of ouabain, an inhibitor of the Na+-K+-ATPase, and bumetanide, an inhibitor of the NKCC on the rates of fluid secretion and the electrolytic composition of the final saliva. I found, that the activity of the Na+-K+-ATPase is important for the modification of DA-stimulated primary saliva during its flow through the stimulated duct system. In contrast, it is not important for modification of the 5-HT-stimulated primary saliva. Inhibition of the Na+-K+-ATPase does not affect rates of DA-stimulated fluid secretion, but it increases the rates of 5-HT-stimulated fluid secretion. Activity of the NKCC is important for both secretory processes: the ion and the fluid secretion. Inhibition of the NKCC results in a significant drop in the rates of fluid secretion after DA- and 5-HT-stimulation, as well as a drop in electrolytic concentrations in the saliva. In the second part of my work, I tried to measure changes in the intracellular ionic concentrations (Ca2+, Na+, and K+) within the acinar cells during a DA- or 5-HT-stimulation. The experiments should be performed by ratiometric imaging. Measurements with the Ca2+-sensitive dye Fura-2 did not show any global increase in the intracellular Ca2+-concentration in the p-cells of the acini. Problems concerning a bad loading of the cells, a strong autofluorescence which changed during the time course of the stimulation, as well as changes in the cell volume were the reason, that no measurements using Na+- or K+-sensitive dyes were performed. In the third part of my work I investigated the intracellular signalling pathways, which activate protein secretion after 5-HT-stimulation of the gland. A modified Bradford Assay was used for measuring the protein content in the final saliva. In a dose-response curve I showed that rates of protein secretion are dependent on the 5-HT-concentrations used to stimulate the glands. In another set of experiments I increased the intracellular concentrations of Ca2+, cAMP and / or cGMP, and measured the protein content in the final saliva. An increase in the intracellular Ca2+-concentration activates only a low rate of protein secretion. After an increase in the intracellular cAMP-concentration a much higher rate of protein secretion can be activated, which is not significantly different from the 5-HT stimulated rate of protein secretion. The cAMP-stimulated protein secretion can be further increased by a simultaneous rise in the intracellular Ca2+-concentration. In contrast, cGMP does not activate protein secretion. Therefore I propose the expression of an adenylyl cyclase activating 5-HT-receptor in the basolateral membrane of the protein secreting c-cells.

  2. Continuous equal channel angular pressing

    DOEpatents

    Zhu, Yuntian T.; Lowe, Terry C.; Valiev, Ruslan Z.; Raab, Georgy J.

    2006-12-26

    An apparatus that continuously processes a metal workpiece without substantially altering its cross section includes a wheel member having an endless circumferential groove, and a stationary constraint die that surrounds the wheel member, covers most of the length of the groove, and forms a passageway with the groove. The passageway has a rectangular shaped cross section. An abutment member projects from the die into the groove and blocks one end of the passageway. The wheel member rotates relative to the die in the direction toward the abutment member. An output channel in the die adjacent the abutment member has substantially the same cross section as the passageway. A metal workpiece is fed through an input channel into the passageway and carried in the groove by frictional drag in the direction towards the abutment member, and is extruded through the output channel without any substantial change in cross section.

  3. Mediation: a response to aid-in-dying and the Supreme Court decision.

    PubMed

    Saulo, M; Wagener, R J; Rothschild, I S

    1998-01-01

    The recent U.S. Supreme Court decision concerning aid-in-dying has drawn attention to the complexity of end-of-life care. The authors summarize the recent Supreme Court's decision and the problems surrounding this complex issue. A case study is provided to demonstrate how mediation facilitates collaborative problem solving. Finally, the authors demonstrate how nurse leaders can apply this three-stage process and its attendant principles to facilitate ethical decision making in end-of-life care.

  4. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Soer, Wouter

    LED luminaires have seen dramatic changes in cost breakdown over the past few years. The LED component cost, which until recently was the dominant portion of luminaire cost, has fallen to a level of the same order as the other luminaire components, such as the driver, housing, optics etc. With the current state of the technology, further luminaire performance improvement and cost reduction is realized most effectively by optimization of the whole system, rather than a single component. This project focuses on improving the integration between LEDs and drivers. Lumileds has developed a light engine platform based on low-cost high-powermore » LEDs and driver topologies optimized for integration with these LEDs on a single substrate. The integration of driver and LEDs enables an estimated luminaire cost reduction of about 25% for targeted applications, mostly due to significant reductions in driver and housing cost. The high-power LEDs are based on Lumileds’ patterned sapphire substrate flip-chip (PSS-FC) technology, affording reduced die fabrication and packaging cost compared to existing technology. Two general versions of PSS-FC die were developed in order to create the desired voltage and flux increments for driver integration: (i) small single-junction die (0.5 mm 2), optimal for distributed lighting applications, and (ii) larger multi-junction die (2 mm 2 and 4 mm 2) for high-power directional applications. Two driver topologies were developed: a tapped linear driver topology and a single-stage switch-mode topology, taking advantage of the flexible voltage configurations of the new PSS-FC die and the simplification opportunities enabled by integration of LEDs and driver on the same board. A prototype light engine was developed for an outdoor “core module” application based on the multi-junction PSS-FC die and the single-stage switch-mode driver. The light engine meets the project efficacy target of 128 lm/W at a luminous flux greater than 4100 lm, a correlated color temperature (CCT) of 4000K and a color rendering index (CRI) greater than 70.« less

  5. Poor Outcomes in a Cohort of HIV-Infected Adolescents Undergoing Treatment for Multidrug-Resistant Tuberculosis in Mumbai, India

    PubMed Central

    Isaakidis, Petros; Paryani, Roma; Khan, Samsuddin; Mansoor, Homa; Manglani, Mamta; Valiyakath, Asmaa; Saranchuk, Peter; Furin, Jennifer

    2013-01-01

    Background Little is known about the treatment of multidrug-resistant tuberculosis (MDR-TB) in HIV-co-infected adolescents. This study aimed to present the intermediate outcomes of HIV-infected adolescents aged 10–19 years receiving second-line anti-TB treatment in a Médecins Sans Frontières (MSF) project in Mumbai, India. Methods A retrospective review of medical records of 11 adolescents enrolled between July 2007 and January 2013 was undertaken. Patients were initiated on either empirical or individualized second-line ambulatory anti-TB treatment under direct observation. Results The median age was 16 (IQR 14–18) years and 54% were female. Five (46%) adolescents had pulmonary TB (PTB), two (18%) extrapulmonary disease (EPTB) and four (36%) had both. Median CD4 count at the time of MDR-TB diagnosis was 162.7 cells/µl (IQR: 84.8–250.5). By January 2013, eight patients had final and 3 had interim outcomes. Favourable results were seen in four (36.5%) patients: one was cured and three were still on treatment with negative culture results. Seven patients (64%) had poor outcomes: four (36.5%) died and three (27%) defaulted. Three of the patients who died never started on antiretroviral and/or TB treatment and one died 16 days after treatment initiation. Two of the defaulted died soon after default. All patients (100%) on-treatment experienced adverse events (AEs): two required permanent discontinuation of the culprit drug and two were hospitalized due to AEs. No patient required permanent discontinuation of the entire second-line TB or antiretroviral regimens. Conclusions Early mortality and mortality after default were the most common reasons for poor outcomes in this study. Early mortality suggests the need for rapid diagnosis and prompt treatment initiation, and adolescents might benefit from active contact-tracing and immediate referral. Default occurred at different times, suggesting the need for continuous, intensified and individualized psychosocial support for co-infected adolescents. Operational research among co-infected adolescents will be especially important in designing effective interventions for this vulnerable group. PMID:23894358

  6. Poor outcomes in a cohort of HIV-infected adolescents undergoing treatment for multidrug-resistant tuberculosis in Mumbai, India.

    PubMed

    Isaakidis, Petros; Paryani, Roma; Khan, Samsuddin; Mansoor, Homa; Manglani, Mamta; Valiyakath, Asmaa; Saranchuk, Peter; Furin, Jennifer

    2013-01-01

    Little is known about the treatment of multidrug-resistant tuberculosis (MDR-TB) in HIV-co-infected adolescents. This study aimed to present the intermediate outcomes of HIV-infected adolescents aged 10-19 years receiving second-line anti-TB treatment in a Médecins Sans Frontières (MSF) project in Mumbai, India. A retrospective review of medical records of 11 adolescents enrolled between July 2007 and January 2013 was undertaken. Patients were initiated on either empirical or individualized second-line ambulatory anti-TB treatment under direct observation. The median age was 16 (IQR 14-18) years and 54% were female. Five (46%) adolescents had pulmonary TB (PTB), two (18%) extrapulmonary disease (EPTB) and four (36%) had both. Median CD4 count at the time of MDR-TB diagnosis was 162.7 cells/µl (IQR: 84.8-250.5). By January 2013, eight patients had final and 3 had interim outcomes. Favourable results were seen in four (36.5%) patients: one was cured and three were still on treatment with negative culture results. Seven patients (64%) had poor outcomes: four (36.5%) died and three (27%) defaulted. Three of the patients who died never started on antiretroviral and/or TB treatment and one died 16 days after treatment initiation. Two of the defaulted died soon after default. All patients (100%) on-treatment experienced adverse events (AEs): two required permanent discontinuation of the culprit drug and two were hospitalized due to AEs. No patient required permanent discontinuation of the entire second-line TB or antiretroviral regimens. Early mortality and mortality after default were the most common reasons for poor outcomes in this study. Early mortality suggests the need for rapid diagnosis and prompt treatment initiation, and adolescents might benefit from active contact-tracing and immediate referral. Default occurred at different times, suggesting the need for continuous, intensified and individualized psychosocial support for co-infected adolescents. Operational research among co-infected adolescents will be especially important in designing effective interventions for this vulnerable group.

  7. Regional vegetation die-off in response to global-change-type drought

    USGS Publications Warehouse

    Breshears, D.D.; Cobb, N.S.; Rich, P.M.; Price, K.P.; Allen, Craig D.; Balice, R.G.; Romme, W.H.; Kastens, J.H.; Floyd, M. Lisa; Belnap, J.; Anderson, J.J.; Myers, O.B.; Meyer, Clifton W.

    2005-01-01

    Future drought is projected to occur under warmer temperature conditions as climate change progresses, referred to here as global-change-type drought, yet quantitative assessments of the triggers and potential extent of drought-induced vegetation die-off remain pivotal uncertainties in assessing climate-change impacts. Of particular concern is regional-scale mortality of overstory trees, which rapidly alters ecosystem type, associated ecosystem properties, and land surface conditions for decades. Here, we quantify regional-scale vegetation die-off across southwestern North American woodlands in 2002-2003 in response to drought and associated bark beetle infestations. At an intensively studied site within the region, we quantified that after 15 months of depleted soil water content, >90% of the dominant, overstory tree species (Pinus edulis, a piñon) died. The die-off was reflected in changes in a remotely sensed index of vegetation greenness (Normalized Difference Vegetation Index), not only at the intensively studied site but also across the region, extending over 12,000 km2 or more; aerial and field surveys confirmed the general extent of the die-off. Notably, the recent drought was warmer than the previous subcontinental drought of the 1950s. The limited, available observations suggest that die-off from the recent drought was more extensive than that from the previous drought, extending into wetter sites within the tree species' distribution. Our results quantify a trigger leading to rapid, drought-induced die-off of overstory woody plants at subcontinental scale and highlight the potential for such die-off to be more severe and extensive for future global-change-type drought under warmer conditions.

  8. Regional vegetation die-off in response to global-change-type drought

    PubMed Central

    Breshears, David D.; Cobb, Neil S.; Rich, Paul M.; Price, Kevin P.; Allen, Craig D.; Balice, Randy G.; Romme, William H.; Kastens, Jude H.; Floyd, M. Lisa; Belnap, Jayne; Anderson, Jesse J.; Myers, Orrin B.; Meyer, Clifton W.

    2005-01-01

    Future drought is projected to occur under warmer temperature conditions as climate change progresses, referred to here as global-change-type drought, yet quantitative assessments of the triggers and potential extent of drought-induced vegetation die-off remain pivotal uncertainties in assessing climate-change impacts. Of particular concern is regional-scale mortality of overstory trees, which rapidly alters ecosystem type, associated ecosystem properties, and land surface conditions for decades. Here, we quantify regional-scale vegetation die-off across southwestern North American woodlands in 2002-2003 in response to drought and associated bark beetle infestations. At an intensively studied site within the region, we quantified that after 15 months of depleted soil water content, >90% of the dominant, overstory tree species (Pinus edulis, a piñon) died. The die-off was reflected in changes in a remotely sensed index of vegetation greenness (Normalized Difference Vegetation Index), not only at the intensively studied site but also across the region, extending over 12,000 km2 or more; aerial and field surveys confirmed the general extent of the die-off. Notably, the recent drought was warmer than the previous subcontinental drought of the 1950s. The limited, available observations suggest that die-off from the recent drought was more extensive than that from the previous drought, extending into wetter sites within the tree species' distribution. Our results quantify a trigger leading to rapid, drought-induced die-off of overstory woody plants at subcontinental scale and highlight the potential for such die-off to be more severe and extensive for future global-change-type drought under warmer conditions. PMID:16217022

  9. Enery Efficient Press and Sinter of Titanium Powder for Low-Cost Components in Vehicle Applications

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Thomas Zwitter; Phillip Nash; Xiaoyan Xu

    2011-03-31

    This is the final technical report for the Department of Energy NETL project NT01931 Energy Efficient Press and Sinter of Titanium Powder for Low-Cost Components in Vehicle Applications. Titanium has been identified as one of the key materials with the required strength that can reduce the weight of automotive components and thereby reduce fuel consumption. Working with newly developed sources of titanium powder, Webster-Hoff will develop the processing technology to manufacture low cost vehicle components using the single press/single sinter techniques developed for iron based powder metallurgy today. Working with an automotive or truck manufacturer, Webster-Hoff will demonstrate the feasibilitymore » of manufacturing a press and sinter titanium component for a vehicle application. The project objective is two-fold, to develop the technology for manufacturing press and sinter titanium components, and to demonstrate the feasibility of producing a titanium component for a vehicle application. The lowest cost method for converting metal powder into a net shape part is the Powder Metallurgy Press and Sinter Process. The method involves compaction of the metal powder in a tool (usually a die and punches, upper and lower) at a high pressure (up to 60 TSI or 827 MPa) to form a green compact with the net shape of the final component. The powder in the green compact is held together by the compression bonds between the powder particles. The sinter process then converts the green compact to a metallurgically bonded net shape part through the process of solid state diffusion. The goal of this project is to expand the understanding and application of press and sinter technology to Titanium Powder applications, developing techniques to manufacture net shape Titanium components via the press and sinter process. In addition, working with a vehicle manufacturer, demonstrate the feasibility of producing a titanium component for a vehicle. This is not a research program, but rather a project to develop a process for press and sinter of net shape Titanium components. All of these project objectives have been successfully completed.« less

  10. John Kay's Civil War: A Multimedia Internet Project for Middle School Social Studies.

    ERIC Educational Resources Information Center

    Olwell, Russell B.

    1999-01-01

    Uses letters of John Kay, a Union Army soldier, to initiate a technology-based project that illustrates reasons for fighting in the Civil War, the daily life of a soldier, and the tragedies families endured. Explains that students learn that history is filled with real people who lived and died for their beliefs. (CMK)

  11. Results from a new die-to-database reticle inspection platform

    NASA Astrophysics Data System (ADS)

    Broadbent, William; Xiong, Yalin; Giusti, Michael; Walsh, Robert; Dayal, Aditya

    2007-03-01

    A new die-to-database high-resolution reticle defect inspection system has been developed for the 45nm logic node and extendable to the 32nm node (also the comparable memory nodes). These nodes will use predominantly 193nm immersion lithography although EUV may also be used. According to recent surveys, the predominant reticle types for the 45nm node are 6% simple tri-tone and COG. Other advanced reticle types may also be used for these nodes including: dark field alternating, Mask Enhancer, complex tri-tone, high transmission, CPL, EUV, etc. Finally, aggressive model based OPC will typically be used which will include many small structures such as jogs, serifs, and SRAF (sub-resolution assist features) with accompanying very small gaps between adjacent structures. The current generation of inspection systems is inadequate to meet these requirements. The architecture and performance of a new die-to-database inspection system is described. This new system is designed to inspect the aforementioned reticle types in die-to-database and die-to-die modes. Recent results from internal testing of the prototype systems are shown. The results include standard programmed defect test reticles and advanced 45nm and 32nm node reticles from industry sources. The results show high sensitivity and low false detections being achieved.

  12. An investigation on fatality of drivers in vehicle-fixed object accidents on expressways in China: Using multinomial logistic regression model.

    PubMed

    Peng, Yong; Peng, Shuangling; Wang, Xinghua; Tan, Shiyang

    2018-06-01

    This study aims to identify the effects of characteristics of vehicle, roadway, driver, and environment on fatality of drivers in vehicle-fixed object accidents on expressways in Changsha-Zhuzhou-Xiangtan district of Hunan province in China by developing multinomial logistic regression models. For this purpose, 121 vehicle-fixed object accidents from 2011-2017 are included in the modeling process. First, descriptive statistical analysis is made to understand the main characteristics of the vehicle-fixed object crashes. Then, 19 explanatory variables are selected, and correlation analysis of each two variables is conducted to choose the variables to be concluded. Finally, five multinomial logistic regression models including different independent variables are compared, and the model with best fitting and prediction capability is chosen as the final model. The results showed that the turning direction in avoiding fixed objects raised the possibility that drivers would die. About 64% of drivers died in the accident were found being ejected out of the car, of which 50% did not use a seatbelt before the fatal accidents. Drivers are likely to die when they encounter bad weather on the expressway. Drivers with less than 10 years of driving experience are more likely to die in these accidents. Fatigue or distracted driving is also a significant factor in fatality of drivers. Findings from this research provide an insight into reducing fatality of drivers in vehicle-fixed object accidents.

  13. UO2 fuel pellets fabrication via Spark Plasma Sintering using non-standard molybdenum die

    NASA Astrophysics Data System (ADS)

    Papynov, E. K.; Shichalin, O. O.; Mironenko, A. Yu; Tananaev, I. G.; Avramenko, V. A.; Sergienko, V. I.

    2018-02-01

    The article investigates spark plasma sintering (SPS) of commercial uranium dioxide (UO2) powder of ceramic origin into highly dense fuel pellets using non-standard die instead of usual graphite die. An alternative and formerly unknown method has been suggested to fabricate UO2 fuel pellets by SPS for excluding of typical problems related to undesirable carbon diffusion. Influence of SPS parameters on chemical composition and quality of UO2 pellets has been studied. Also main advantages and drawbacks have been revealed for SPS consolidation of UO2 in non-standard molybdenum die. The method is very promising due to high quality of the final product (density 97.5-98.4% from theoretical, absence of carbon traces, mean grain size below 3 μm) and mild sintering conditions (temperature 1100 ºC, pressure 141.5 MPa, sintering time 25 min). The results are interesting for development and probable application of SPS in large-scale production of nuclear ceramic fuel.

  14. OA39 Digging a hole… planting a seed… water it and watch it start to grow, grow, grow.

    PubMed

    Lloyd, Rebecca; McLoughlin, Kathleen; McGloughlin, Carmelia; Macken, Caroline; Richardson, Marie; Rhatigan, Jim

    2015-04-01

    Milford Care Centre's Compassionate Communities Project uses a seed grant scheme to engage with communities around illness, dying, death and bereavement. The scheme, now in it's 3(rd) cycle strives to inspire and support the work of local groups, organisations and individuals who wish to mark in some tangible way their response to the universal realities of death, dying, loss and care as lived and experienced by those living within their communities. A key requirement for the receipt of a grant is that the level of funding must be matched either in cash or in kind. This presentation will report on the projects supported, describing the short and medium term impact they have had on the local community. A short film will showcase the projects. Qualitative interviews were conducted with all grant recipients to determine the impact of the seed grant at a community level. Seed grants were used in a variety of ways, for example: Supporting a community group to develop a reflection space Supporting a youth project to explore what death, dying, loss and care means to service users through the creative arts. Supporting a library to develop a bereavement information 'resource'. Supporting local groups to run a community event aimed at increasing awareness and knowledge about 'healthy' ways of coping with loss and grief. Supporting those seeking practical ways of providing support to other living with illness and loss. The seed grant scheme offers a low cost, high impact approach to working with communities. © 2015, Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

  15. Measuring attitudes towards the dying process: A systematic review of tools.

    PubMed

    Groebe, Bernadette; Strupp, Julia; Eisenmann, Yvonne; Schmidt, Holger; Schlomann, Anna; Rietz, Christian; Voltz, Raymond

    2018-04-01

    At the end of life, anxious attitudes concerning the dying process are common in patients in Palliative Care. Measurement tools can identify vulnerabilities, resources and the need for subsequent treatment to relieve suffering and support well-being. To systematically review available tools measuring attitudes towards dying, their operationalization, the method of measurement and the methodological quality including generalizability to different contexts. Systematic review according to the PRISMA Statement. Methodological quality of tools assessed by standardized review criteria. MEDLINE, PsycINFO, PsyndexTests and the Health and Psychosocial Instruments were searched from their inception to April 2017. A total of 94 identified studies reported the development and/or validation of 44 tools. Of these, 37 were questionnaires and 7 alternative measurement methods (e.g. projective measures). In 34 of 37 questionnaires, the emotional evaluation (e.g. anxiety) towards dying is measured. Dying is operationalized in general items ( n = 20), in several specific aspects of dying ( n = 34) and as dying of others ( n = 14). Methodological quality of tools was reported inconsistently. Nine tools reported good internal consistency. Of 37 tools, 4 were validated in a clinical sample (e.g. terminal cancer; Huntington disease), indicating questionable generalizability to clinical contexts for most tools. Many tools exist to measure attitudes towards the dying process using different endpoints. This overview can serve as decision framework on which tool to apply in which contexts. For clinical application, only few tools were available. Further validation of existing tools and potential alternative methods in various populations is needed.

  16. Archaeometric study on minting dies produced under papal rule in Ferrara

    NASA Astrophysics Data System (ADS)

    Monticelli, Cecilia; Balbo, Andrea; Vaccaro, Carmela; Gulinelli, Maria Teresa; Garagnani, Gian Luca

    2013-12-01

    In the Civic Museum of Palazzo Schifanoia in Ferrara, a collection of 1104 coin striking tools is stored. Among these, eight steel dies produced from the 2nd decade of the seventeenth to the half of the eighteenth century, representative of the whole period of activity of the papal mint in Ferrara, have been chosen and studied. In that period, while important innovations in the coin minting technique were introduced in Europe, Ferrara declined from the rank of ducal mint to that of peripheral minting center of the highly centralized Papal States. The dies have been characterized by metallographic, chemical, and microhardness investigations. The results suggest that the dies were obtained by a manual smithing technique consisting in hammer hot forging. The die quality improved with time. In fact, in the period 1619-1622, a hardening treatment for the engraved die end consisting in a simple local carburization coexisted with a more efficient production method, based on the application of a proper final heat treatment. This treatment induced a graded microstructure from the engraved end, with a hard martensitic or bainitic structure, to the opposite end, with a tough ferritic/pearlitic structure. From 1675 onward, the latter production method was applied on all the studied dies. The chemical analysis of the alloys suggest that they were likely obtained from iron ores with a common provenance, while the analysis of the slag inclusions suggests the adoption of a direct method of ironmaking throughout the activity period of the mint.

  17. Tobacco and the Movies

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Glantz, Stanton

    The principal aim of this roadmap is to place the US and Fermilab in the best position to host the International Linear Collider (ILC). The strategy must be resilient against the many vicissitudes that will attend the development of such a large project. Pier Oddone will explore the tension between the needed concentration of effort to move a project as large as the ILC forward and the need to maintain the breadth of our field. America's leading health organizations agree. Smoking on screen is the #1 recruiter of new adolescent smokers in the United States - 390,000 kids a year,more » of whom 120,000 will die from tobacco-caused diseases. That's more Americans than die from drunk driving, criminal violence, illicit drugs, and HIV/AIDS combined. Why does Hollywood still promote smoking? Is it corrupt? Or stupid?« less

  18. Death and caring for dying patients: exploring first-year nursing students' descriptive experiences.

    PubMed

    Ek, Kristina; Westin, Lars; Prahl, Charlotte; Osterlind, Jane; Strang, Susann; Bergh, Ingrid; Hammarlund, Kina

    2014-10-01

    To describe first-year nursing students' experiences of witnessing death and providing end-of-life care. This study is part of a larger longitudinal project. Interviews (n=17) were conducted with nursing students at the end of their first year of education. To analyse the interviews (lived-experience descriptions), a thematic analysis, 'a search for meaning' ( Van Manen, 1997 ) was applied. The results are presented within the framework of four separate themes: (1) The thought of death is more frightening than the actual experience, (2) Daring to approach the dying patient and offering something of oneself, (3) The experience of not sufficing in the face of death and (4) Being confronted with one's own feelings. Nursing students require continuous support and opportunity to reflect and discuss their experiences about caring for dying patients and confronting death throughout the entirety of their education. In addition, teachers and clinical supervisors need to give support using reflective practice to help students to develop confidence in their capacity for caring for dying patients.

  19. Differences in place of death between lung cancer and COPD patients: a 14-country study using death certificate data.

    PubMed

    Cohen, Joachim; Beernaert, Kim; Van den Block, Lieve; Morin, Lucas; Hunt, Katherine; Miccinesi, Guido; Cardenas-Turanzas, Marylou; Onwuteaka-Philipsen, Bregje; MacLeod, Rod; Ruiz-Ramos, Miguel; Wilson, Donna M; Loucka, Martin; Csikos, Agnes; Rhee, Yong-Joo; Teno, Joan; Ko, Winne; Deliens, Luc; Houttekier, Dirk

    2017-03-03

    Chronic obstructive pulmonary disease and lung cancer are leading causes of death with comparable symptoms at the end of life. Cross-national comparisons of place of death, as an important outcome of terminal care, between people dying from chronic obstructive pulmonary disease and lung cancer have not been studied before. We collected population death certificate data from 14 countries (year: 2008), covering place of death, underlying cause of death, and demographic information. We included patients dying from lung cancer or chronic obstructive pulmonary disease and used descriptive statistics and multivariable logistic regressions to describe patterns in place of death. Of 5,568,827 deaths, 5.8% were from lung cancer and 4.4% from chronic obstructive pulmonary disease. Among lung cancer decedents, home deaths ranged from 12.5% in South Korea to 57.1% in Mexico, while hospital deaths ranged from 27.5% in New Zealand to 77.4% in France. In chronic obstructive pulmonary disease patients, the proportion dying at home ranged from 10.4% in Canada to 55.4% in Mexico, while hospital deaths ranged from 41.8% in Mexico to 78.9% in South Korea. Controlling for age, sex, and marital status, patients with chronic obstructive pulmonary disease were significantly less likely die at home rather than in hospital in nine countries. Our study found in almost all countries that those dying from chronic obstructive pulmonary disease as compared with those from lung cancer are less likely to die at home and at a palliative care institution and more likely to die in a hospital or a nursing home. This might be due to less predictable disease trajectories and prognosis of death in chronic obstructive pulmonary disease. IMPROVING END-OF-LIFE CARE: Structured palliative care similar to that offered to cancer sufferers should be in place for patients with chronic lung disease. Joachim Cohen at Vrije University in Brussels and co-workers examined international death certificate data collected from 14 countries to determine place of death for patients with lung cancer and chronic obstructive pulmonary disease (COPD). While patients with COPD suffer similar symptoms to lung cancer in their final days, few COPD patients receive palliative care or achieve the common wish of dying at home. This may be partly due to the inherent unpredictability of final-stage COPD compared with lung cancer. Cohen's team found that, with the exception of Italy, Spain, and Mexico, patients with COPD were significantly more likely to die in hospital than at home. They highlight the need for improved COPD palliative care provision.

  20. The Effects of Die Relief Agent on the Retention of Full Coverage Castings,

    DTIC Science & Technology

    1981-02-19

    autopolymerizing resin. A diamond rotary instrument and a high speed dental handpiece using air- water coolant were employed to prepare the crown of each tooth...777 109 502 ARMY INST OF DENTAL RESEARCH WASHINGTON DC F/6 6/5 THE EFFECTS OF DIE RELIEF AGENT ON THE RETENTION OF FULL COYERA--ETC(U) FES 81 S 6...Kuffler" 4W Eugene F.Huget, COL, (Ret.) .9. PERFORMING ORGANIZATION NAME AND ADDRESS 10. PROGRAM ELEMENT. PROJECT, TASK U.S. Army Institute of Dental

  1. Energy Saving Melting and Revert Reduction Technology: Melting Efficiency in Die Casting Operations

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    David Schwam

    2012-12-15

    This project addressed multiple aspects of the aluminum melting and handling in die casting operations, with the objective of increasing the energy efficiency while improving the quality of the molten metal. The efficiency of melting has always played an important role in the profitability of aluminum die casting operations. Consequently, die casters need to make careful choices in selecting and operating melting equipment and procedures. The capital cost of new melting equipment with higher efficiency can sometimes be recovered relatively fast when it replaces old melting equipment with lower efficiency. Upgrades designed to improve energy efficiency of existing equipment maymore » be well justified. Energy efficiency is however not the only factor in optimizing melting operations. Melt losses and metal quality are also very important. Selection of melting equipment has to take into consideration the specific conditions at the die casting shop such as availability of floor space, average quantity of metal used as well as the ability to supply more metal during peaks in demand. In all these cases, it is essential to make informed decisions based on the best available data.« less

  2. Hydraulic and carbohydrate changes in experimental drought-induced mortality of saplings in two conifer species.

    PubMed

    Anderegg, William R L; Anderegg, Leander D L

    2013-03-01

    Global patterns of drought-induced forest die-off indicate that many forests may be sensitive to climate-driven mortality, but the lack of understanding of how trees and saplings die during drought hinders the projections of die-off, demographic bottlenecks and ecosystem trajectories. In this study, we performed a severe controlled drought experiment on saplings of Pinus edulis Engelm. and Juniperus osteosperma (Torr.) Little, two species that both experienced die-off in a recent 'climate change-type' drought. We examined the roles of carbohydrate and hydraulic changes in multiple tissues as the saplings died. We found that saplings of both species exhibited large degrees of loss of hydraulic conductivity prior to death. Neither species exhibited significant changes in carbohydrate concentrations in any tissue during the relatively short and severe imposed drought. Native hydraulic conductivity successfully predicted the degree of canopy mortality in both species, highlighting the importance of drought characteristics and tree attributes in influencing physiological pathways to mortality. The relationships elucidated here, as well as the differences between our results and previous findings in adult trees, can help inform mortality mechanisms in climate-vegetation models, especially for young trees, and to understand species response to severe drought across ontogeny.

  3. 20 CFR 410.650 - Dismissal for cause.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ..., Finality of Decisions, and Representation of Parties § 410.650 Dismissal for cause. The presiding officer... provided in § 410.669. (d) Death of party. Where the party who filed the hearing request dies and there is...

  4. Springback Compensation Process for High Strength Steel Automotive Parts

    NASA Astrophysics Data System (ADS)

    Onhon, M. Fatih

    2016-08-01

    This paper is about an advanced stamping simulation methodology used in automotive industry to shorten total die manufacturing times in a new vehicle project by means of benefiting leading edge virtual try-out technology.

  5. Hot-melt co-extrusion: requirements, challenges and opportunities for pharmaceutical applications.

    PubMed

    Vynckier, An-Katrien; Dierickx, Lien; Voorspoels, Jody; Gonnissen, Yves; Remon, Jean Paul; Vervaet, Chris

    2014-02-01

    Co-extrusion implies the simultaneous hot-melt extrusion of two or more materials through the same die, creating a multi-layered extrudate. It is an innovative continuous production technology that offers numerous advantages over traditional pharmaceutical processing techniques. This review provides an overview of the co-extrusion equipment, material requirements and medical and pharmaceutical applications. The co-extrusion equipment needed for pharmaceutical production has been summarized. Because the geometrical design of the die dictates the shape of the final product, different die types have been discussed. As one of the major challenges at the moment is shaping the final product in a continuous way, an overview of downstream solutions for processing co-extrudates into drug products is provided. Layer adhesion, extrusion temperature and viscosity matching are pointed out as most important requirements for material selection. Examples of medical and pharmaceutical applications are presented and some recent findings considering the production of oral drug delivery systems have been summarized. Co-extrusion provides great potential for the continuous production of fixed-dose combination products which are gaining importance in pharmaceutical industry. There are still some barriers to the implementation of co-extrusion in the pharmaceutical industry. The optimization of downstream processing remains a point of attention. © 2013 Royal Pharmaceutical Society.

  6. Simulation of 7050 Wrought Aluminum Alloy Wheel Die Forging and its Defects Analysis based on DEFORM

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Huang Shiquan; Yi Youping; Zhang Yuxun

    2010-06-15

    Defects such as folding, intercrystalline cracking and flow lines outcrop are very likely to occur in the forging of aluminum alloy. Moreover, it is difficult to achieve the optimal set of process parameters just by trial and error within an industrial environment. In producing 7050 wrought aluminum alloy wheel, a rigid-plastic finite element method (FEM) analysis has been performed to optimize die forging process. Processing parameters were analyzed, focusing on the effects of punch speed, friction factor and temperature. Meanwhile, mechanism as well as the evolution with respect to the defects of the wrought wheel was studied in details. Frommore » an analysis of the results, isothermal die forging was proposed for producing 7050 aluminum alloy wheel with good mechanical properties. Finally, verification experiment was carried out on hydropress.« less

  7. Experiences and Expressions of Spirituality at the End of Life in the Intensive Care Unit.

    PubMed

    Swinton, Marilyn; Giacomini, Mita; Toledo, Feli; Rose, Trudy; Hand-Breckenridge, Tracy; Boyle, Anne; Woods, Anne; Clarke, France; Shears, Melissa; Sheppard, Robert; Cook, Deborah

    2017-01-15

    The austere setting of the intensive care unit (ICU) can suppress expressions of spirituality. To describe how family members and clinicians experience and express spirituality during the dying process in a 21-bed medical-surgical ICU. Reflecting the care of 70 dying patients, we conducted 208 semistructured qualitative interviews with 76 family members and 150 clinicians participating in the Three Wishes Project. Interviews were recorded and transcribed verbatim. Data were analyzed by three investigators using qualitative interpretive description. Participants characterize dying as a spiritual event. Spirituality is an integral part of the life narrative of the patient before, during, and after death. Experiences and expressions of spirituality for patients, families, and clinicians during end-of-life care in the ICU are supported by eliciting and implementing wishes in several ways. Eliciting wishes stimulates conversations for people of diverse spiritual orientations to respond to death in personally meaningful ways that facilitate continuity and closure, and ease emotional trauma. Soliciting wishes identifies positive aspirations, which provide comfort in the face of death. The act of soliciting wishes brings clinician humanity to the fore. Wishing makes individual spiritual preferences and practices more accessible. Wishes may be grounded in spiritual goals, such as peace, comfort, connections, and tributes; they may seek a spiritually enhanced environment or represent specific spiritual interventions. Family members and clinicians consider spirituality an important dimension of end-of-life care. The Three Wishes Project invites and supports the expression of myriad forms of spirituality during the dying process in the ICU.

  8. Being a hospice volunteer influenced medical students' comfort with dying and death: a pilot study.

    PubMed

    Stecho, Will; Khalaf, Roy; Prendergast, Patrick; Geerlinks, Ashley; Lingard, Lorelei; Schulz, Valerie

    2012-01-01

    Being comfortable with death and communicating with patients near the end of life are important attributes in palliative care. We developed a hospice volunteer program to teach these attitudes and skills to preclinical medical students. Using a mixed-methods approach, validated surveys measured participants' and non-participants fear of death and communication apprehension regarding dying. Journals and focus groups examined participants' subjective experiences as their patient relationships evolved. Survey scores were significantly lower for participant hospice volunteers, indicating lower levels of death anxiety and communication apprehension regarding dying. An explanatory framework, using journals and focus groups, captured participants' sense of development over time into three categories: challenges, learning, and growth. This pilot project provides insight into the medical students' experiential learning as they participate in our hospice volunteer program.

  9. The Cedar Project: mortality among young Indigenous people who use drugs in British Columbia

    PubMed Central

    Jongbloed, Kate; Pearce, Margo E.; Pooyak, Sherri; Zamar, David; Thomas, Vicky; Demerais, Lou; Christian, Wayne M.; Henderson, Earl; Sharma, Richa; Blair, Alden H.; Yoshida, Eric M.; Schechter, Martin T.; Spittal, Patricia M.

    2017-01-01

    BACKGROUND: Young Indigenous people, particularly those involved in the child welfare system, those entrenched in substance use and those living with HIV or hepatitis C, are dying prematurely. We report mortality rates among young Indigenous people who use drugs in British Columbia and explore predictors of mortality over time. METHODS: We analyzed data collected every 6 months between 2003 and 2014 by the Cedar Project, a prospective cohort study involving young Indigenous people who use illicit drugs in Vancouver and Prince George, BC. We calculated age-standardized mortality ratios using Indigenous and Canadian reference populations. We identified predictors of mortality using time-dependent Cox proportional hazard regression. RESULTS: Among 610 participants, 40 died between 2003 and 2014, yielding a mortality rate of 670 per 100 000 person-years. Young Indigenous people who used drugs were 12.9 (95% confidence interval [CI] 9.2–17.5) times more likely to die than all Canadians the same age and were 7.8 (95% CI 5.6–10.6) times more likely to die than Indigenous people with Status in BC. Young women and those using drugs by injection were most affected. The leading causes of death were overdose (n = 15 [38%]), illness (n = 11 [28%]) and suicide (n = 5 [12%]). Predictors of mortality included having hepatitis C at baseline (adjusted hazard ratio [HR] 2.76, 95% CI 1.47–5.16), previous attempted suicide (adjusted HR 1.88, 95% CI 1.01–3.50) and recent overdose (adjusted HR 2.85, 95% CI 1.00–8.09). INTERPRETATION: Young Indigenous people using drugs in BC are dying at an alarming rate, particularly young women and those using injection drugs. These deaths likely reflect complex intersections of historical and present-day injustices, substance use and barriers to care. PMID:29109208

  10. Results from prototype die-to-database reticle inspection system

    NASA Astrophysics Data System (ADS)

    Mu, Bo; Dayal, Aditya; Broadbent, Bill; Lim, Phillip; Goonesekera, Arosha; Chen, Chunlin; Yeung, Kevin; Pinto, Becky

    2009-03-01

    A prototype die-to-database high-resolution reticle defect inspection system has been developed for 32nm and below logic reticles, and 4X Half Pitch (HP) production and 3X HP development memory reticles. These nodes will use predominantly 193nm immersion lithography (with some layers double patterned), although EUV may also be used. Many different reticle types may be used for these generations including: binary (COG, EAPSM), simple tritone, complex tritone, high transmission, dark field alternating (APSM), mask enhancer, CPL, and EUV. Finally, aggressive model based OPC is typically used, which includes many small structures such as jogs, serifs, and SRAF (sub-resolution assist features), accompanied by very small gaps between adjacent structures. The architecture and performance of the prototype inspection system is described. This system is designed to inspect the aforementioned reticle types in die-todatabase mode. Die-to-database inspection results are shown on standard programmed defect test reticles, as well as advanced 32nm logic, and 4X HP and 3X HP memory reticles from industry sources. Direct comparisons with currentgeneration inspection systems show measurable sensitivity improvement and a reduction in false detections.

  11. Ascaris lumbricoides egg die-off in an experimental excreta storage system and public health implication in Vietnam.

    PubMed

    Vu-Van, Tu; Pham-Duc, Phuc; Winkler, Mirko S; Zurbrügg, Christian; Zinsstag, Jakob; Le Thi Thanh, Huong; Bich, Tran Huu; Nguyen-Viet, Hung

    2017-02-01

    We studied the influence of different additive materials (lime, and rice husk) and aeration conditions on Ascaris lumbricoides egg die-off in 24 vaults of an experimental excreta storage unit. Excreta samples were collected once every two weeks over a 181-day period. Temperature, pH, and moisture content were recorded. A. lumbricoides eggs were quantitatively analyzed by the Romanenko method, which identified and counted live and dead eggs. From the first sampling (0 storage day) to the final sampling (181 storage days) the average percentage of viable A. lumbricoides eggs decreased gradually from 76.72 ± 11.23% (mean ± SD) to 8.26 ± 5.20%. The storage time and the high pH value significantly increased the die-off of helminth eggs. Over 181 storage days, all vaults option effectively reduced A. lumbricoides eggs die-off. The best vault option, with aeration and 10% lime per total weight, met the WHO standard for excreta treatment on the 111th storage day.

  12. Fabrication process analysis and experimental verification for aluminum bipolar plates in fuel cells by vacuum die-casting

    NASA Astrophysics Data System (ADS)

    Jin, Chul Kyu; Kang, Chung Gil

    2011-10-01

    There are various methods for the fabrication of bipolar plates, but these are still limited to machining and stamping processes. High-pressure die casting (HPDC) is an ideal process for the manufacture of bipolar plates This study aims to investigate the formability of bipolar plates for polymer electrolyte membrane fuel cells (PEMFCs) fabricated by vacuum HPDC of an Al-Mg alloy (ALDC6). The cavity of the mold consisted of a thin-walled plate (200 mm × 200 mm × 0.8 mm) with a layer of serpentine channel (50 mm × 50 mm). The location and direction of the channel in the final mold design was determined by computational simulation (MAGMA soft). In addition, simulation results for different conditions of plunger stroke control were compared to those from actual die-casting experiments. Under a vacuum pressure of 35 kPa and for injection speeds of 0.3 and 2.5 m s-1 in the low and high speed regions, respectively, the samples had few casting defects. In addition, the hardness was higher and porosity in microstructure was less than those of the samples made under other injection speed conditions. In case of thin-walled plates, vacuum die casting is beneficial in terms of formability compared to conventional die casting.

  13. Modeling and Analysis of Deformation for Spiral Bevel Gear in Die Quenching Based on the Hardenability Variation

    NASA Astrophysics Data System (ADS)

    Zhang, Yingtao; Wang, Gang; Shi, Wankai; Yang, Lin; Li, Zhichao

    2017-07-01

    Spiral bevel gears are widely used to transmit energy between intersecting axes. The strength and fatigue life of the gears are improved by carburizing and quenching. A die quenching process is used to control the deformation of the gear. The deformation is determined by the variations in the hardenability for a certain die quenching process. The relationship between hardenability, phase transformation and deformation needs to be studied to minimize deformation during the adjustment of the die quenching process parameters. In this paper, material properties for 22CrMoH steel are determined by the results of Jominy tests, dilatometry experiments and static mechanical property tests. The material models were built based on testing results under the consideration of hardenability variation. An finite element analysis model was developed to couple the phase transformation and deformation history of the complete carburizing and die quenching process for the spiral bevel gears. The final microstructures in the gear were bainite for low hardenability steel and a mixture of bainite and ferrite for high hardenability steel. The largest buckling deformation at the gear bottom surface is 0.375 mm at the outer circle for the low hardenability gear and 0.091 mm at the inner circle for the high hardenability gear.

  14. Bridge deck cracking and composite action analyses : final report, March 2010.

    DOT National Transportation Integrated Search

    2010-03-01

    According to the American Society of Civil Engineers Report Card (ASCE, 2005), United States infrastructure received a grade point average of "D"(i.e., poor rating) in 2005. Moreover, the National Bridge Inventory (Federal Highway Administration, 200...

  15. Competency-Based Transfer Pilot Project--Final Report. Executive Summary [and] Competency-Based Transfer Pilot Project: Final Report on House Bill 1909

    ERIC Educational Resources Information Center

    Washington Higher Education Coordinating Board, 2006

    2006-01-01

    This publication contains the following: (1) Competency-Based Transfer Pilot Project--Final Report. Executive Summary (January 2006); and (2) Competency-Based Transfer Pilot Project: Final Report on House Bill 1909 (January 2005). In 2003, the legislature and governor enacted House Bill 1909 to create a pilot project on competency-based transfer…

  16. 5 CFR 470.311 - Final project approval.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... MANAGEMENT RESEARCH PROGRAMS AND DEMONSTRATIONS PROJECTS Regulatory Requirements Pertaining to Demonstration Projects § 470.311 Final project approval. (a) The Office of Personnel Management will consider all timely...) The Office of Personnel Management shall provide a copy of the final version of the project plan to...

  17. Robot-based additive manufacturing for flexible die-modelling in incremental sheet forming

    NASA Astrophysics Data System (ADS)

    Rieger, Michael; Störkle, Denis Daniel; Thyssen, Lars; Kuhlenkötter, Bernd

    2017-10-01

    The paper describes the application concept of additive manufactured dies to support the robot-based incremental sheet metal forming process (`Roboforming') for the production of sheet metal components in small batch sizes. Compared to the dieless kinematic-based generation of a shape by means of two cooperating industrial robots, the supporting robot models a die on the back of the metal sheet by using the robot-based fused layer manufacturing process (FLM). This tool chain is software-defined and preserves the high geometrical form flexibility of Roboforming while flexibly generating support structures adapted to the final part's geometry. Test series serve to confirm the feasibility of the concept by investigating the process challenges of the adhesion to the sheet surface and the general stability as well as the influence on the geometric accuracy compared to the well-known forming strategies.

  18. Blanking and piercing theory, applications and recent experimental results

    NASA Astrophysics Data System (ADS)

    Zaid, Adnan l. O.

    2014-06-01

    Blanking and piercing are manufacturing processes by which certain geometrical shapes are sheared off a sheet metal. If the sheared off part is the one required, the processes referred to as blanking and if the remaining part in the sheet is the one required, the process is referred to as piercing. In this paper, the theory and practice of these processes are reviewed and discussed The main parameters affecting these processes are presented and discussed. These include: the radial clearance percentage, punch and die geometrical parameters, for example punch and die profile radii. The abovementioned parameters on the force and energy required to effect blanking together with their effect on the quality of the products are also presented and discussed. Recent experimental results together with photomacrographs and photomicrographs are also included and discussed. Finally, the effect of punch and die wear on the quality of the blanks is alsogiven and discussed.

  19. A Battle of Words: "Dignity" and "Peace" in the Writings of Elisabeth Kübler-Ross.

    PubMed

    Burnier, Daniel

    2017-04-01

    This article analyzes the writings of Elisabeth Kübler-Ross through the discursive lens of the phrase "dying with dignity." For her, the phrase meant allowing someone to die comfortably his/her own death. This phrase has to be understood in relationship with the final "stage of acceptance" of her model. Describing this key part of her well-known scientific output, she often used, in the early 1970s, the phrase "dying in peace and dignity." An evaluation of the evidence suggests that because the concept of dignity was co-opted by the pro-euthanasia movement during this decade, the language of dignity was little by little abandoned by her. In later years, only "peace" survived from her favorite expression. Although this concept of peace remains present to the end in all Kübler-Ross writings, the pro-euthanasia movement has also started to speak the language of peace.

  20. Gaining consensus on family carer needs when caring for someone dying at home to develop the Carers' Alert Thermometer (CAT): a modified Delphi study.

    PubMed

    Knighting, Katherine; O'Brien, Mary R; Roe, Brenda; Gandy, Rob; Lloyd-Williams, Mari; Nolan, Mike; Jack, Barbara A

    2016-01-01

    To report a multi-phase modified Delphi study conducted with carers and professionals to identify the priority areas for inclusion in an alert screening tool for carers providing support to someone dying at home. Internationally, there is a growing emphasis on increasing choice for patients who wish to die at home which relies heavily on care provided by the unpaid family carers. Family carers can have high levels of unmet needs comprising their psychological and physical health and their ability to provide effective care and support. Development of an alert tool to identify carers' needs in everyday practice required identification and consensus of the priority areas of need for inclusion. Multi-phase modified Delphi study and instrument development. Qualitative and quantitative data collection took place between 2011-2013 with 111 carers and 93 professionals to identify carers' needs and gain consensus on the priority areas for inclusion in the alert tool. An expert panel stage and final evidence review post-Delphi were used. The Delphi panels had high levels of agreement and consensus. Ten areas of carer need across two themes of 'the current caring situation' and 'the carer's own health and well-being' were prioritized for inclusion in the alert tool. An optional end-of-life planning question was included following the final stages. The results provide evidence of carers' needs to be assessed, areas for consideration in the education of those who support carers and someone dying at home and targeting of services, while demonstrating the usefulness and adaptability of the Delphi method. © 2015 The Authors. Journal of Advanced Nursing Published by John Wiley & Sons Ltd.

  1. Cancer-related symptoms most concerning to parents during the last week and last day of their child's life.

    PubMed

    Pritchard, Michele; Burghen, Elizabeth; Srivastava, Deo Kumar; Okuma, James; Anderson, Lisa; Powell, Brent; Furman, Wayne L; Hinds, Pamela S

    2008-05-01

    Studies of symptoms in children dying a cancer-related death typically rely on medical chart reviews or parental responses to symptom checklists. However, the mere presence of a symptom does not necessarily correspond with the distress it can cause the child's parents. The purpose of this study was to identify the cancer-related symptoms that most concerned parents during the last days of their child's life and the strategies parents identified as helpful with their child's care. Sixty-five parents of 52 children who had died a cancer-related death within the previous 6 to 10 months participated in telephone interviews. Eligibility criteria included being the parent or guardian of a child aged 0 to 21 years who had died within the previous 6 to 10 months after being treated at a pediatric cancer center, having been with their child during the last week of the child's life, speaking English, being willing to participate, and having access to a telephone. Eighteen symptoms of concern were identified as occurring during their child's final week and final day of life. The most frequently reported symptoms at both times included changes in behavior, changes in appearance, pain, weakness and fatigue, and breathing changes. The proportion of reported symptoms did not differ according to patient gender, disease, or location of death (intensive care, elsewhere in the hospital, or home). The most helpful strategies used by health care professionals to assist the child or parents included giving pain and anxiety medications, spending time with the child or family, providing competent care, and giving advice. This knowledge can guide professionals in preparing parents for the symptoms that a child imminently dying of cancer is likely to experience and in providing care that will be helpful to parents.

  2. Evolutions of Advanced Stamping CAE — Technology Adventures and Business Impact on Automotive Dies and Stamping

    NASA Astrophysics Data System (ADS)

    Wang, Chuantao (C. T.)

    2005-08-01

    In the past decade, sheet metal forming and die development has been transformed to a science-based and technology-driven engineering and manufacturing enterprise from a tryout-based craft. Stamping CAE, especially the sheet metal forming simulation, as one of the core components in digital die making and digital stamping, has played a key role in this historical transition. The stamping simulation technology and its industrial applications have greatly impacted automotive sheet metal product design, die developments, die construction and tryout, and production stamping. The stamping CAE community has successfully resolved the traditional formability problems such as splits and wrinkles. The evolution of the stamping CAE technology and business demands opens even greater opportunities and challenges to stamping CAE community in the areas of (1) continuously improving simulation accuracy, drastically reducing simulation time-in-system, and improving operationalability (friendliness), (2) resolving those historically difficult-to-resolve problems such as dimensional quality problems (springback and twist) and surface quality problems (distortion and skid/impact lines), (3) resolving total manufacturability problems in line die operations including blanking, draw/redraw, trim/piercing, and flanging, and (4) overcoming new problems in forming new sheet materials with new forming techniques. In this article, the author first provides an overview of the stamping CAE technology adventures and achievements, and industrial applications in the past decade. Then the author presents a summary of increasing manufacturability needs from the formability to total quality and total manufacturability of sheet metal stampings. Finally, the paper outlines the new needs and trends for continuous improvements and innovations to meet increasing challenges in line die formability and quality requirements in automotive stamping.

  3. Quality of dying and death with cancer in Israel.

    PubMed

    Braun, Michal; Hasson-Ohayon, Ilanit; Hales, Sarah; Zimmermann, Camilla; Rydall, Anne; Peretz, Tamar; Rodin, Gary

    2014-07-01

    The quality of dying and death refers to the evaluation of the final days of life and the moment of death with respect to how it is prepared for, faced and experienced by those with a terminal illness. It includes experience in multiple domains: physical, psychological, social, spiritual or existential, the nature of health care, life closure and death preparation, and the circumstances of death. To explore the quality of dying and death in cancer patients in Israel and its relationship to place of death and socio-demographic characteristics of the primary caregivers and the deceased. Retrospective assessment of the quality of dying and death, based on caregiver responses to the Quality of Dying and Death (QODD) questionnaire (overall score ranges from 0 to 100; higher scores reflect better dying and death experiences) 8 to 10 months after the death. Ninety-five caregivers of Jewish cancer patients, most of whom were female spouses or children of the deceased. Mean QODD score was 57.2 (standard deviation [SD]=15), which is in the low-moderate range. Place of death, gender and age of the caregiver, and age of the deceased, were associated with QODD score. This retrospective study in Israel demonstrated that the overall quality of dying and death was regarded as poor by almost half of the caregivers. These findings may reflect the relative lack of specialized palliative care and advance care planning in Israel at the time of this study, which took place between 2006 and 2009. Further research and enhancement of palliative care resources may be needed in Israel and several encouraging recent developments (e.g. staff training and legislation) suggest that such changes are now underway.

  4. Impact of Simulation Technology on Die and Stamping Business

    NASA Astrophysics Data System (ADS)

    Stevens, Mark W.

    2005-08-01

    Over the last ten years, we have seen an explosion in the use of simulation-based techniques to improve the engineering, construction, and operation of GM production tools. The impact has been as profound as the overall switch to CAD/CAM from the old manual design and construction methods. The changeover to N/C machining from duplicating milling machines brought advances in accuracy and speed to our construction activity. It also brought significant reductions in fitting sculptured surfaces. Changing over to CAD design brought similar advances in accuracy, and today's use of solid modeling has enhanced that accuracy gain while finally leading to the reduction in lead time and cost through the development of parametric techniques. Elimination of paper drawings for die design, along with the process of blueprinting and distribution, provided the savings required to install high capacity computer servers, high-speed data transmission lines and integrated networks. These historic changes in the application of CAE technology in manufacturing engineering paved the way for the implementation of simulation to all aspects of our business. The benefits are being realized now, and the future holds even greater promise as the simulation techniques mature and expand. Every new line of dies is verified prior to casting for interference free operation. Sheet metal forming simulation validates the material flow, eliminating the high costs of physical experimentation dependent on trial and error methods of the past. Integrated forming simulation and die structural analysis and optimization has led to a reduction in die size and weight on the order of 30% or more. The latest techniques in factory simulation enable analysis of automated press lines, including all stamping operations with corresponding automation. This leads to manufacturing lines capable of running at higher levels of throughput, with actual results providing the capability of two or more additional strokes per minute. As we spread these simulation techniques to the balance of our business, from blank de-stacking to the racking of parts, we anticipate continued reduction in lead-time and engineering expense while improving quality and start-up execution. The author will provide an overview of technology and business evolution of the math-based process that brought an historical transition and revitalization to the die and stamping industry in the past decade. Finally, the author will give an outlook for future business needs and technology development directions.

  5. Temperature sensitivity of drought-induced tree mortality portends increased regional die-off under global-change-type drought

    PubMed Central

    Adams, Henry D.; Guardiola-Claramonte, Maite; Barron-Gafford, Greg A.; Villegas, Juan Camilo; Breshears, David D.; Zou, Chris B.; Troch, Peter A.; Huxman, Travis E.

    2009-01-01

    Large-scale biogeographical shifts in vegetation are predicted in response to the altered precipitation and temperature regimes associated with global climate change. Vegetation shifts have profound ecological impacts and are an important climate-ecosystem feedback through their alteration of carbon, water, and energy exchanges of the land surface. Of particular concern is the potential for warmer temperatures to compound the effects of increasingly severe droughts by triggering widespread vegetation shifts via woody plant mortality. The sensitivity of tree mortality to temperature is dependent on which of 2 non-mutually-exclusive mechanisms predominates—temperature-sensitive carbon starvation in response to a period of protracted water stress or temperature-insensitive sudden hydraulic failure under extreme water stress (cavitation). Here we show that experimentally induced warmer temperatures (≈4 °C) shortened the time to drought-induced mortality in Pinus edulis (piñon shortened pine) trees by nearly a third, with temperature-dependent differences in cumulative respiration costs implicating carbon starvation as the primary mechanism of mortality. Extrapolating this temperature effect to the historic frequency of water deficit in the southwestern United States predicts a 5-fold increase in the frequency of regional-scale tree die-off events for this species due to temperature alone. Projected increases in drought frequency due to changes in precipitation and increases in stress from biotic agents (e.g., bark beetles) would further exacerbate mortality. Our results demonstrate the mechanism by which warmer temperatures have exacerbated recent regional die-off events and background mortality rates. Because of pervasive projected increases in temperature, our results portend widespread increases in the extent and frequency of vegetation die-off. PMID:19365070

  6. At-home palliative sedation for end-of-life cancer patients.

    PubMed

    Alonso-Babarro, Alberto; Varela-Cerdeira, Maria; Torres-Vigil, Isabel; Rodríguez-Barrientos, Ricardo; Bruera, Eduardo

    2010-07-01

    Using a decision-making and treatment checklist developed to facilitate the at-home palliative sedation process, we assessed the incidence and efficacy of palliative sedation for end-of-life cancer patients with intractable symptoms who died at home. We retrospectively reviewed the medical records of 370 patients who were followed by a palliative home care team. Twenty-nine of 245 patients (12%) who died at home had received palliative sedation. The mean age of the patients who received palliative sedation was 58 +/- 17 years, and the mean age of the patients who did not receive palliative sedation was 69 +/- 15 years (p = 0.002). No other differences were detected between patients who did or did not receive palliative sedation. The most common indications for palliative sedation were delirium (62%) and dyspnea (14%). Twenty-seven patients (93%) received midazolam for palliative sedation (final mean dose of 74 mg), and two (7%) received levomepromazine (final mean dose of 125 mg). The mean time between palliative sedation initiation and time of death was 2.6 days. In 13 of the cases (45%), the palliative sedation decision was made with the patient and his or her family members, and in another 13 patients (45%), the palliative sedation decision was made only with the patient's family members. We concluded that palliative sedation may be used safely and efficaciously to treat dying cancer patients with refractory symptoms at home.

  7. Titanium dental copings prepared by a powder metallurgy method: a preliminary report.

    PubMed

    Eriksson, Mikael; Andersson, Matts; Carlström, Elis

    2004-01-01

    The purpose of this study was to determine if the Procera pressed-powder method can be used to fabricate titanium copings. Commercially pure titanium powder was used to prepare the copings. The powder was pressed onto an enlarged tooth preparation die of aluminum using cold isostatic pressing. The outer shape of the coping was formed using a Procera milling machine, and the copings were vacuum sintered. Titanium copings could be prepared using this method. The density of the sintered copings reached 97% to 99%+ of theoretic density, and the copings showed ductile behavior after sintering. Enlarging the tooth preparation die to compensate for the sintering shrinkage could optimize the final size of the copings. Ductile and dense titanium dental copings can be produced with powder-metal processing using cold isostatic pressing, followed by milling and sintering to final shape. The forming technique has, if properly optimized, a potential of becoming a more cost-efficient production method than spark erosion.

  8. Big Biology: Supersizing Science During the Emergence of the 21st Century

    PubMed Central

    Vermeulen, Niki

    2017-01-01

    Ist Biologie das jüngste Mitglied in der Familie von Big Science? Die vermehrte Zusammenarbeit in der biologischen Forschung wurde in der Folge des Human Genome Project zwar zum Gegenstand hitziger Diskussionen, aber Debatten und Reflexionen blieben meist im Polemischen verhaftet und zeigten eine begrenzte Wertschätzung für die Vielfalt und Erklärungskraft des Konzepts von Big Science. Zur gleichen Zeit haben Wissenschafts- und Technikforscher/innen in ihren Beschreibungen des Wandels der Forschungslandschaft die Verwendung des Begriffs Big Science gemieden. Dieser interdisziplinäre Artikel kombiniert eine begriffliche Analyse des Konzepts von Big Science mit unterschiedlichen Daten und Ideen aus einer Multimethodenuntersuchung mehrerer großer Forschungsprojekte in der Biologie. Ziel ist es, ein empirisch fundiertes, nuanciertes und analytisch nützliches Verständnis von Big Biology zu entwickeln und die normativen Debatten mit ihren einfachen Dichotomien und rhetorischen Positionen hinter sich zu lassen. Zwar kann das Konzept von Big Science als eine Mode in der Wissenschaftspolitik gesehen werden – inzwischen vielleicht sogar als ein altmodisches Konzept –, doch lautet meine innovative Argumentation, dass dessen analytische Verwendung unsere Aufmerksamkeit auf die Ausweitung der Zusammenarbeit in den Biowissenschaften lenkt. Die Analyse von Big Biology zeigt Unterschiede zu Big Physics und anderen Formen von Big Science, namentlich in den Mustern der Forschungsorganisation, der verwendeten Technologien und der gesellschaftlichen Zusammenhänge, in denen sie tätig ist. So können Reflexionen über Big Science, Big Biology und ihre Beziehungen zur Wissensproduktion die jüngsten Behauptungen über grundlegende Veränderungen in der Life Science-Forschung in einen historischen Kontext stellen. PMID:27215209

  9. Programmed cell death as a defence against infection

    PubMed Central

    Jorgensen, Ine; Rayamajhi, Manira; Miao, Edward A.

    2017-01-01

    Eukaryotic cells can die from physical trauma, resulting in necrosis. Alternately, they can die via programmed cell death upon stimulation of specific signalling pathways. Here we discuss the utility of four cell death pathways in innate immune defence against bacterial and viral infection: apoptosis, necroptosis, pyroptosis and NETosis. We describe the interactions that interweave different programmed cell death pathways, which create complex signalling networks that cross-guard each other in the evolutionary arms race with pathogens. Finally, we describe how the resulting cell corpses — apoptotic bodies, pore-induced intracellular traps (PITs) and neutrophil extracellular traps (NETs) — promote clearance of infection. PMID:28138137

  10. Cast Metals Coalition Technology Transfer and Program Management Final Report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gwyn, Mike

    2009-03-31

    The Cast Metals Coalition (CMC) partnership program was funded to ensure that the results of the Department of Energy's (DOE) metalcasting research and development (R&D) projects are successfully deployed into industry. Specifically, the CMC program coordinated the transfer and deployment of energy saving technologies and process improvements developed under separately funded DOE programs and projects into industry. The transition of these technologies and process improvements is a critical step in the path to realizing actual energy savings. At full deployment, DOE funded metalcasting R&D results are projected to save 55% of the energy used by the industry in 1998. Thismore » closely aligns with DOE's current goal of driving a 25% reduction in industrial energy intensity by 2017. In addition to benefiting DOE, these energy savings provide metalcasters with a significant economic advantage. Deployment of already completed R&D project results and those still underway is estimated to return over 500% of the original DOE and industry investment. Energy savings estimates through December 2008 from the Energy-Saving Melting and Revert Reduction Technology (E-SMARRT) portfolio of projects alone are 12 x 1012 BTUs, with a projection of over 50 x 1012 BTUs ten years after program completion. These energy savings and process improvements have been made possible through the unique collaborative structure of the CMC partnership. The CMC team consists of DOE's Office of Industrial Technology, the three leading metalcasting technical societies in the U.S: the American Foundry Society; the North American Die Casting Association; and the Steel Founders Society of America; and the Advanced Technology Institute (ATI), a recognized leader in distributed technology management. CMC provides collaborative leadership to a complex industry composed of approximately 2,100 companies, 80% of which employ less than 100 people, and only 4% of which employ more than 250 people. Without collaboration, new technologies enabling energy efficiencies and environment-friendly improvements are slow to develop, and have trouble obtaining a broad application. The CMC team was able to effectively and efficiently transfer the results of DOE's metalcasting R&D projects to industry by utilizing and delivering the numerous communication vehicles identified in the proposal. The three metalcasting technical associations achieved significant technology transition results under this program. In addition to reaching over 23,000 people per year through Modern Casting and 28,000 through Engineered Casting Solutions, AFS had 84 national publications and reached over 1,200 people annually through Cast Metals Institute (CMI) education courses. NADCA's education department reached over 1,000 people each year through their courses, in addition to reaching over 6,000 people annually through Die Casting Engineer, and publishing 58 papers. The SFSA also published 99 research papers and reached over 1,000 people annually through their member newsletters. In addition to these communication vehicles, the CMC team conducted numerous technical committee meetings, project reviews, and onsite visits. All of these efforts to distribute the latest metalcasting technologies contributed to the successful deployment of DOE's R&D projects into industry. The DOE/CMC partnership demonstrated significant success in the identification and review of relevant and easy-to-implement metalcasting energy-saving processes and technologies so that the results are quickly implemented and become general practice. The results achieved in this program demonstrate that sustained technology transfer efforts are a critical step in the deployment of R&D projects to industry.« less

  11. 5 CFR 470.311 - Final project approval.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 470.311 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PERSONNEL... Projects § 470.311 Final project approval. (a) The Office of Personnel Management will consider all timely...) The Office of Personnel Management shall provide a copy of the final version of the project plan to...

  12. Industrial Technology Modernization Program. Project 28. Automation of Receiving, Receiving Inspection and Stores

    DTIC Science & Technology

    1987-06-15

    001 GENERAL DYNAMICS 00 FORT WORTH DIVISION INDUSTRIAL TECHNOLOGY MODERNIZATION PROGRAM Phase 2 Final Project Repc t JUNG 0 ?7 PROJECT 28 AUTOMATION...DYNAMICS FORT WORTH DIVISION INDUSTRIAL TECHNOLOGY MODERNIZATION PROGRAM Phase 2 Final Project Report PROJECT 28 AUTOMATION OF RECEIVING, RECEIVING...13 6 PROJECT ASSUMPTIONS 20 7 PRELIMINARY/FINAL DESIGN AND FINDINGS 21 8 SYSTEM/EQUIPMENT/MACHINING SPECIFICATIONS 37 9 VENDOR/ INDUSTRY ANALYSIS

  13. Experiences with and attitudes toward death and dying among homeless persons.

    PubMed

    Song, John; Ratner, Edward R; Bartels, Dianne M; Alderton, Lucy; Hudson, Brenda; Ahluwalia, Jasjit S

    2007-04-01

    Homeless persons face many barriers to health care, have few resources, and experience high death rates. They live lives of disenfranchisement and neglect. Few studies have explored their experiences and attitudes toward death and dying. Unfortunately, studies done in other populations may not apply to homeless persons. Exploring these experiences and attitudes may provide insight into life, health care, and end-of-life (EOL) concerns of this population. To explore the experiences and attitudes toward death and dying among homeless persons. Qualitative study utilizing focus groups. Fifty-three homeless persons recruited from homeless service agencies. In-depth interviews, which were audiotaped and transcribed. We present seven themes, some of which are previously unreported. Homeless persons described many significant experiences with death and dying, and many participants suffered losses while very young. These encounters influenced participants' attitudes toward risks and risky behavior: e.g., for some, these experiences provided justification for high-risk behaviors and influenced their behaviors while living on the streets. For others, they may be associated with their homelessness. Finally, these experiences informed their attitudes toward death and dying as well as EOL care; homeless persons believe that care will be poor at the EOL. Findings from this study have implications for addressing social services, health promotion, prevention, and EOL care for homeless persons, as well as for others who are poor and disenfranchised.

  14. Experiences With and Attitudes Toward Death and Dying Among Homeless Persons

    PubMed Central

    Ratner, Edward R; Bartels, Dianne M.; Alderton, Lucy; Hudson, Brenda; Ahluwalia, Jasjit S.

    2007-01-01

    Background Homeless persons face many barriers to health care, have few resources, and experience high death rates. They live lives of disenfranchisement and neglect. Few studies have explored their experiences and attitudes toward death and dying. Unfortunately, studies done in other populations may not apply to homeless persons. Exploring these experiences and attitudes may provide insight into life, health care, and end-of-life (EOL) concerns of this population. Objective To explore the experiences and attitudes toward death and dying among homeless persons. Design Qualitative study utilizing focus groups. Participants Fifty-three homeless persons recruited from homeless service agencies. Measurements In-depth interviews, which were audiotaped and transcribed. Results We present seven themes, some of which are previously unreported. Homeless persons described many significant experiences with death and dying, and many participants suffered losses while very young. These encounters influenced participants’ attitudes toward risks and risky behavior: e.g., for some, these experiences provided justification for high-risk behaviors and influenced their behaviors while living on the streets. For others, they may be associated with their homelessness. Finally, these experiences informed their attitudes toward death and dying as well as EOL care; homeless persons believe that care will be poor at the EOL. Conclusions Findings from this study have implications for addressing social services, health promotion, prevention, and EOL care for homeless persons, as well as for others who are poor and disenfranchised. PMID:17372788

  15. Continental-scale consequences of tree die-offs in North America: identifying where forest loss matters most

    NASA Astrophysics Data System (ADS)

    Swann, Abigail L. S.; Laguë, Marysa M.; Garcia, Elizabeth S.; Field, Jason P.; Breshears, David D.; Moore, David J. P.; Saleska, Scott R.; Stark, Scott C.; Villegas, Juan Camilo; Law, Darin J.; Minor, David M.

    2018-05-01

    Regional-scale tree die-off events driven by drought and warming and associated pests and pathogens have occurred recently on all forested continents and are projected to increase in frequency and extent with future warming. Within areas where tree mortality has occurred, ecological, hydrological and meteorological consequences are increasingly being documented. However, the potential for tree die-off to impact vegetation processes and related carbon dynamics in areas remote to where die-off occurs has rarely been systematically evaluated, particularly for multiple distinct regions within a given continent. Such remote impacts can occur when climate effects of local vegetation change are propagated by atmospheric circulation—the phenomena of ‘ecoclimate teleconnections’. We simulated tree die-off events in the 13 most densely forested US regions (selected from the 20 US National Ecological Observatory Network [NEON] domains) and found that tree die-off even for smaller regions has potential to affect climate and hence Gross Primary Productivity (GPP) in disparate regions (NEON domains), either positively or negatively. Some regions exhibited strong teleconnections to several others, and some regions were relatively sensitive to tree loss regardless of what other region the tree loss occurred in. For the US as a whole, loss of trees in the Pacific Southwest—an area undergoing rapid tree die-off—had the largest negative impact on remote US GPP whereas loss of trees in the Mid-Atlantic had the largest positive impact. This research lays a foundation for hypotheses that identify how the effects of tree die-off (or other types of tree loss such as deforestation) can ricochet across regions by revealing hot-spots of forcing and response. Such modes of connectivity have direct applicability for improving models of climate change impacts and for developing more informed and coordinated carbon accounting across regions.

  16. In-Hospital Resource Use and Medical Costs in the Last Year of Life by Mode of Death (From the HF-ACTION Randomized Controlled Trial)

    PubMed Central

    Reed, Shelby D.; Li, Yanhong; Dunlap, Mark E.; Kraus, William E.; Samsa, Gregory P.; Schulman, Kevin A.; Zile, Michael R.; Whellan, David J.

    2012-01-01

    Patterns of medical resource use near the end of life may differ across modes of death. We characterized patterns of inpatient resource use and direct costs for patients with HF who died of sudden cardiac death (SCD), HF, other cardiovascular causes, or noncardiovascular causes during the last year of life. Data were from a randomized trial exercise training in patients with HF. Mode of death was adjudicated by an end point committee. We used generalized estimating equations to compare hospitalizations, inpatient days, and inpatient costs incurred during the final year of life among patients who died of different causes, adjusting for clinical and treatment characteristics. Of 2331 patients enrolled in the trial, 231 died after at least 1 year of follow-up with an adjudicated mode of death, including 72 of SCD, 80 of HF, 34 of other cardiovascular causes, and 45 of noncardiovascular causes. Patients who died of SCD were younger, had less severe HF, and incurred fewer hospitalizations, fewer inpatient days, and lower inpatient costs than patients who died of other causes. After adjustment for patient characteristics, inpatient resource use varied by 2 to 4 times across modes of death, suggesting that cost-effectiveness analyses of interventions that reduce mortality from SCD compared with other causes should incorporate mode-specific end-of-life costs. In conclusion, resource use and associated medical costs in the last year of life differed markedly among patients with HF who experienced SCD and patients who died of other causes. PMID:22762718

  17. Let him not be alone: perspectives of older British South Asian minority ethnic patients on dying in acute hospitals.

    PubMed

    Venkatasalu, Munikumar Ramasamy

    2017-09-02

    To investigate older British South Asians' views on dying at acute hospitals. Older people, including those from ethnic minorities prefer 'home as a haven' for their last days of life; however, they are more likely to die in hospital. Constructive grounded theory was used as a methodological approach that informed data collection to data analysis. Open meetings with 11 local South Asian community organisations enabled the researchers to recruit a total of 55 older South Asians in this study. Data were collected using gender-based focus groups (n=5) and in-depth, semi-structured interviews (n=29). Transcripts were analysed using Nvivo 9. Three key themes were identified: 'mistrust', 'let him not be alone' and 'family as a protective shield'. The theme 'mistrust' is explored through examination of beliefs, attitudes and expectations about 'hospital' as a place in the care of the dying. The theme of 'let him not be alone' draws the family's preferences and concerns in relation to leaving their older dying relative alone in the hospital. The final theme of 'family as a protective shield' describes the element of family care as a protective shield for their older one to have peaceful end-of-life care moments in the hospital. Allowing older relatives to die in hospital seems to evoke feelings of missed filial responsibilities and guilt among family carers among older ethnic minorities. The presence of cultural paranoia and mistrust often led minorities to experience sub-standard end-of-life care in acute hospitals.

  18. Prevalence of drugs and alcohol in fatal civil aviation accidents between 1994 and 1998 : final report.

    DOT National Transportation Integrated Search

    2000-06-01

    The use of drugs and alcohol in aviation is closely monitored by the FAA Office of Aviation Medicine's (OAMs) Civil Aeromedical Institute (CAMI) through the toxicological analysis of specimens from pilots who have died in aviation accidents. This ...

  19. Use of the Palmaz stent in the treatment of severe tracheomalacia.

    PubMed

    Geller, Kenneth A; Wells, Winfield J; Koempel, Jeffrey A; St John, Maie A R

    2004-08-01

    To present our experience with the use of the Palmaz stent in treating cases of severe, life-threatening tracheomalacia, and to report our experience with the use of tracheal stents in patients who have concomitant tracheotomies, we performed a retrospective study in a tertiary-care children's hospital. Nine patients with multiple congenital anomalies including severe tracheomalacia required placement of a Palmaz stent to prolong life. The congenital anomalies included congenital heart disease, congenital lung disease, meningomyelocele, laryngotracheoesophageal cleft, and tracheoesophageal fistula. Three of the patients had concomitant tracheotomies. Each patient had placement of one or more Palmaz stents in the trachea and/or bronchus. Four patients died, and 5 patients are still alive. Three of the 4 patients who died had concomitant tracheotomies and died of complications associated with significant tracheal hemorrhage. The fourth died of pulmonary complications following repeated episodes of pneumonia. None of the 5 patients who are still alive had a concomitant tracheotomy. The Palmaz stent is a useful tool for treating life-threatening tracheomalacia as a final resort in this difficult patient population; however, the use of these stents may lead to subsequent hemorrhage and death, especially in patients with tracheotomies, so their use must be carefully considered.

  20. Increasing Prediction the Original Final Year Project of Student Using Genetic Algorithm

    NASA Astrophysics Data System (ADS)

    Saragih, Rijois Iboy Erwin; Turnip, Mardi; Sitanggang, Delima; Aritonang, Mendarissan; Harianja, Eva

    2018-04-01

    Final year project is very important forgraduation study of a student. Unfortunately, many students are not seriouslydidtheir final projects. Many of studentsask for someone to do it for them. In this paper, an application of genetic algorithms to predict the original final year project of a studentis proposed. In the simulation, the data of the final project for the last 5 years is collected. The genetic algorithm has several operators namely population, selection, crossover, and mutation. The result suggest that genetic algorithm can do better prediction than other comparable model. Experimental results of predicting showed that 70% was more accurate than the previous researched.

  1. CSP Manufacturing Challenges and Assembly Reliability

    NASA Technical Reports Server (NTRS)

    Ghaffarian, Reza

    2000-01-01

    Although the expression of CSP is widely used by industry from suppliers to users, its implied definition had evolved as the technology has matured. There are "expert definition"- package that is up to 1.5 time die- or "interim definition". CSPs are miniature new packages that industry is starting to implement and there are many unresolved technical issues associated with their implementation. For example, in early 1997, packages with 1 mm pitch and lower were the dominant CSPs, whereas in early 1998 packages with 0.8 mm and lower became the norm for CSPs. Other changes included the use of flip chip die rather than wire bond in CSP. Nonetheless the emerging CSPs are competing with bare die assemblies and are becoming the package of choice for size reduction applications. These packages provide the benefits of small size and performance of the bare die or flip chip, with the advantage of standard die packages. The JPL-led MicrotypeBGA Consortium of enterprises representing government agencies and private companies have jointed together to pool in-kind resources for developing the quality and reliability of chip scale packages (CSPs) for a variety of projects. This talk will cover specifically the experience of our consortium on technology implementation challenges, including design and build of both standard and microvia boards, assembly of two types of test vehicles, and the most current environmental thermal cycling test results.

  2. Automation Study for Longhorn Army Ammunition Plant Hand Held Signal Flight Assembly, Rocket Barrel Assembly, 40 MM Signal, Final Packaging/Pack-Out, and Star Finishing

    DTIC Science & Technology

    1990-03-01

    J.B. Webb Jonesboro , AR Farmington, MI Crimping Press Joraco Drake Corp. Smithfield, RI Phoenix, AZ Die Cutter Roll Cut Peerless Machinery Co. Harbour...be taken are detailed for each assembly procedure. The report provides overall system integration requirements. The layouts of the two manufacturing...buildings are detailed. Several component changes to the Hand Held Signals are proposed. None of these will affect the operation of the-final product

  3. Tree die-off in response to global change-type drought: Mortality insights from a decade of plant water potential measurements

    USGS Publications Warehouse

    Breshears, D.D.; Myers, O.B.; Meyer, Clifton W.; Barnes, F.J.; Zou, C.B.; Allen, Craig D.; McDowell, N.G.; Pockman, W. T.

    2009-01-01

    Global climate change is projected to produce warmer, longer, and more frequent droughts, referred to here as “global change-type droughts”, which have the potential to trigger widespread tree die-off. However, drought-induced tree mortality cannot be predicted with confidence, because long-term field observations of plant water stress prior to, and culminating in, mortality are rare, precluding the development and testing of mechanisms. Here, we document plant water stress in two widely distributed, co-occurring species, piñon pine (Pinus edulis) and juniper (Juniperus monosperma), over more than a decade, leading up to regional-scale die-off of piñon pine trees in response to global change-related drought. Piñon leaf water potentials remained substantially below their zero carbon assimilation point for at least 10 months prior to dying, in contrast to those of juniper, which rarely dropped below their zero-assimilation point. These data suggest that piñon mortality was driven by protracted water stress, leading to carbon starvation and associated increases in susceptibility to other disturbances (eg bark beetles), a finding that should help to improve predictions of mortality during drought.

  4. The contribution of a MOOC to community discussions around death and dying.

    PubMed

    Tieman, Jennifer; Miller-Lewis, Lauren; Rawlings, Deb; Parker, Deborah; Sanderson, Christine

    2018-02-20

    Advances in medicine have helped many to live longer lives and to be able to meet health challenges. However death rates are anticipated to increase given the ageing population and chronic disease progression. Being able to talk about death is seen to be important in normalising death as part of life and supporting preparedness for death. Massive Open Online Courses (MOOCs) provide opportunities for the community to engage in collaborative learning. A 5 week MOOC was developed covering four main topics (language and humour, representations of death, medicalisation of dying, and digital dying) aiming: To enable participants to openly and supportively discuss and learn about issues around living, death and dying, To explore the normally unheard opinions and views of Australians around death and dying, and To determine what effect online learning and discussions offered through the MOOC had on participants' feelings and attitudes towards death and dying. Data was captured on engagement rates in the various MOOC activities. Death Attitudes were measured by five items representing the MOOC's learning objectives and completed at enrolment and conclusion. MOOC Satisfaction was measured with six items at the end of the MOOC. Descriptive statistics were produced for each variable and Chi-Square Tests of Independence assessed the extent of the relationship between categorical variables. Socio-demographic variables were examined as predictors of the outcome variables of MOOC engagement, MOOC satisfaction, and death attitudes. Ethical approval was received from Flinders University Social and Behavioural Research Ethics Committee (Project No. 7247). One thousand one hundred fifty six people enrolled in the Dying2Learn MOOC with 895 participating in some way. Enrolees were primarily female (92.1%). Age ranged from 16 to 84 (mean = 49.5, SD = 12.3). MOOC satisfaction scores were high. Responses to the experience of participating in the MOOC were very positive, with mean scores ranging from 4.3 to 4.6 (aligning with agreement and strong agreement to statements on the value of participating). Death Attitudes were positive at commencement but increased significantly following participation. The Dying2Learn MOOC provided an environment that enabled open and supportive discussion around death and dying and influenced attitudinal change.

  5. 9 CFR 113.452 - Erysipelothrix Rhusiopathiae Antibody.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... die from erysipelas within 7 days post-challenge, the test is invalid. All dead mice shall be examined... found unsatisfactory by a prescribed test shall not be released. (a) Each serial shall meet the applicable general requirements provided in § 113.450. (b) Potency test. Bulk or final container samples of...

  6. Development of western spruce budworm on Douglas-fir callus tissue.

    Treesearch

    Roy C. Beckwith; Barry Goldfarb

    1991-01-01

    The success of feeding and development of western spruce budworm (Choristoneura occidentalis Freeman) on callus tissue of Douglas-fir (Pseudotsuga menziesii (Mirb.) Franco) was determined. Fewer insects died when fed pure callus tissue than when fed on standard diet or callus incorporated into the standard diet. The final...

  7. 76 FR 7500 - Indian Trust Management Reform-Implementation of Statutory Changes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-10

    ... changes also affect the purchase of small fractional interests at probate by restricting who may purchase without consent and what interests may be purchased without consent. DATES: This interim final rule is.... Purchase at Probate B. Permanent Improvements 1. Rule of Descent When Decedent Died Intestate 2...

  8. Process waste assessment: Petroleum jelly removal from semiconductor die using trichloroethylene

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Curtin, D.P.

    The process analyzed involves non-production, laboratory environment use of trichloroethylene for the cleaning of semiconductor devices. The option selection centered on the replacement of the trichloroethylene with a non-hazardous material. This process waste assessment was performed as part of a pilot project.

  9. 76 FR 12096 - McCloud-Pit Project; Notice of Availability of the Final Environmental Impact Statement for the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-04

    ... Project; Notice of Availability of the Final Environmental Impact Statement for the Mccloud-Pit... Pit Rivers in Shasta County, California and has prepared a final environmental impact statement (EIS... and the alternatives for relicensing the McCloud-Pit Project. The final EIS documents the views of...

  10. 49 CFR 268.21 - Down-selection of one or more Maglev projects for further study and selection of one project for...

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... further study and selection of one project for final design, engineering, and construction funding. 268.21... and selection of one project for final design, engineering, and construction funding. (a) Upon... analyses necessary prior to initiation of construction. Final design and engineering work will also be...

  11. 49 CFR 268.21 - Down-selection of one or more Maglev projects for further study and selection of one project for...

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... further study and selection of one project for final design, engineering, and construction funding. 268.21... and selection of one project for final design, engineering, and construction funding. (a) Upon... analyses necessary prior to initiation of construction. Final design and engineering work will also be...

  12. 49 CFR 268.21 - Down-selection of one or more Maglev projects for further study and selection of one project for...

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... further study and selection of one project for final design, engineering, and construction funding. 268.21... and selection of one project for final design, engineering, and construction funding. (a) Upon... analyses necessary prior to initiation of construction. Final design and engineering work will also be...

  13. 49 CFR 268.21 - Down-selection of one or more Maglev projects for further study and selection of one project for...

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... further study and selection of one project for final design, engineering, and construction funding. 268.21... and selection of one project for final design, engineering, and construction funding. (a) Upon... analyses necessary prior to initiation of construction. Final design and engineering work will also be...

  14. 49 CFR 268.21 - Down-selection of one or more Maglev projects for further study and selection of one project for...

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... further study and selection of one project for final design, engineering, and construction funding. 268.21... and selection of one project for final design, engineering, and construction funding. (a) Upon... analyses necessary prior to initiation of construction. Final design and engineering work will also be...

  15. Implementation of Polyurea Applications for Wastewater System Corrosion-Mitigation Projects: Final Report on Project F15-AR04

    DTIC Science & Technology

    2017-07-24

    Corrosion-Mitigation Projects Final Report on Project F15-AR04 Co ns tr uc tio n En gi ne er in g R es ea rc h La bo ra to ry Clint A. Wilson...2017 Implementation of Polyurea Applications for Wastewater System Corrosion-Mitigation Projects Final Report on Project F15-AR04 Clint A...Secretary of Defense Washington, DC 20301-3090 Under Project F15-AR04, “Polyurea Coating for Rehabilitation of Concrete and Metal Infrastructure

  16. REBL: design progress toward 16 nm half-pitch maskless projection electron beam lithography

    NASA Astrophysics Data System (ADS)

    McCord, Mark A.; Petric, Paul; Ummethala, Upendra; Carroll, Allen; Kojima, Shinichi; Grella, Luca; Shriyan, Sameet; Rettner, Charles T.; Bevis, Chris F.

    2012-03-01

    REBL (Reflective Electron Beam Lithography) is a novel concept for high speed maskless projection electron beam lithography. Originally targeting 45 nm HP (half pitch) under a DARPA funded contract, we are now working on optimizing the optics and architecture for the commercial silicon integrated circuit fabrication market at the equivalent of 16 nm HP. The shift to smaller features requires innovation in most major subsystems of the tool, including optics, stage, and metrology. We also require better simulation and understanding of the exposure process. In order to meet blur requirements for 16 nm lithography, we are both shrinking the pixel size and reducing the beam current. Throughput will be maintained by increasing the number of columns as well as other design optimizations. In consequence, the maximum stage speed required to meet wafer throughput targets at 16 nm will be much less than originally planned for at 45 nm. As a result, we are changing the stage architecture from a rotary design to a linear design that can still meet the throughput requirements but with more conventional technology that entails less technical risk. The linear concept also allows for simplifications in the datapath, primarily from being able to reuse pattern data across dies and columns. Finally, we are now able to demonstrate working dynamic pattern generator (DPG) chips, CMOS chips with microfabricated lenslets on top to prevent crosstalk between pixels.

  17. Recent developments in the reform of English law on assisted suicide.

    PubMed

    Shaw, Julia J A

    2009-12-01

    Assisted suicide remains a deeply contested issue in the U.K. Recently three Assisted Dying for the Terminally Ill Bills were introduced in a three year period, all of which failed. Despite the provision of clear and precise safeguards, at each reading the House of Lords fixed largely on the traditional slippery slope and sanctity of life positions; a disproportionate reliance on theological determinism in particular prevented informed rational debate. People are living longer often with chronic, incurable diseases and palliative care is frequently of poor quality or even unavailable in the U.K. and it is unacceptable that individuals 'suffering unbearably' in their final days have no available domestic alternative. Yet the courts have consistently declined to prosecute in cases where friends and relatives have accompanied terminally ill persons abroad to die, against the provisions of the 1961 Suicide Act s2(1). This article critically assesses recent developments in English law on assisted dying and considers the implications for a more inclusive and reasoned debate in the future.

  18. Characterization of DP600 Steel Subject to Electrohydraulic Forming

    NASA Astrophysics Data System (ADS)

    McCallum, Brent

    Electrohydraulic forming (EHF) is a manufacturing technique that transforms electrical energy into work. In EHF, a shockwave is produced as a result of a high-voltage electrical discharge between two electrodes in a water chamber, which travels through water toward the sheet and forms it into the final shape at high velocity. Strain rates can reach 10 4 s-1 in EHF. DP600 dual phase steel was formed in the Nakazima test in quasi-static (QS) condition, and EHF, performed without a mating die (free forming) and using a 34° conical die (die forming). The sheets were etched with a grid prior to testing to determine strains across each specimen. Analysis of voids was carried out to investigate the micro-mechanisms of failure in DP600 steel formed in these three processes. Nakazima specimens exhibited uniform strain behaviour up to 0.65 effective strain; EHFF up to 0.45 effective strain; and EHDF up to 0.7 effective strain.

  19. Design of an electron projection system with slider lenses and multiple beams

    NASA Astrophysics Data System (ADS)

    Moonen, Daniel; Leunissen, Peter L. H. A.; de Jager, Patrick W.; Kruit, Pieter; Bleeker, Arno J.; Van der Mast, Karel D.

    2002-07-01

    The commercial applicability of electron beam projection lithography systems may be limited at high resolution because of low throughput. The main limitations to the throughput are: (i) Beam current. The Coulomb interaction between electrons result in an image blue. Therefore less beam current can be allowed at higher resolution, impacting the illuminate time of the wafer. (ii) Exposure field size. Early attempts to improve throughput with 'full chip' electron beam projection systems failed, because the system suffered from large off-axis aberrations of the electron optics, which severely restricted the useful field size. This has impact on the overhead time. A new type of projection optics will be proposed in this paper to overcome both limits. A slider lens is proposed that allows an effective field that is much larger than schemes proposed by SCALPEL and PREVAIL. The full width of the die can be exposed without mechanical scanning by sliding the beam through the slit-like bore of the lens. Locally, at the beam position, a 'round'-lens field is created with a combination of a rectangular magnetic field and quadruples that are positioned inside the lens. A die can now be exposed during a single mechanical scan as in state-of-the-art light optical tools. The total beam current can be improved without impact on the Coulomb interaction blur by combining several beams in a single lithography system if these beams do not interfere with each other. Several optical layouts have been proposed that combined up to 5 beams in a projection system consisting of a doublet of slider lenses. This type of projection optics has a potential throughput of 50 WPH at 45 nm with a resist sensitivity of 6 (mu) C/cm2.

  20. Early estimate of motor vehicle traffic fatalities in 2009 : a brief statistical summary

    DOT National Transportation Integrated Search

    2010-03-01

    statistical projection of traffic fatalities in 2009 shows that an estimated 33,963 people died in motor vehicle traffic crashes. This represents a decline of about 8.9 percent as compared to the 37,261 fatalities that occurred in 2008, as shown in T...

  1. Development of a web-based tool for projecting costs of managing emerald ash borer in municipal forests

    Treesearch

    Clifford S. Sadof

    2009-01-01

    City managers faced with the invasion of emerald ash borer into their urban forests need to plan for the invasion in order to obtain the resources they need to protect the public from harm caused by dying ash trees. Currently, city...

  2. Final-Year Projects as a Major Element in the IE Curriculum

    ERIC Educational Resources Information Center

    Vitner, G.; Rozenes, S.

    2009-01-01

    This paper presents a multi-perspective view of the final-year project of an industrial engineering and management (IEM) department. The final year project is a major element of a 4-year curriculum within any engineering discipline. Such a project gives the student an opportunity to use and implement methods, techniques and tools that he or she…

  3. Saving Material with Systematic Process Designs

    NASA Astrophysics Data System (ADS)

    Kerausch, M.

    2011-08-01

    Global competition is forcing the stamping industry to further increase quality, to shorten time-to-market and to reduce total cost. Continuous balancing between these classical time-cost-quality targets throughout the product development cycle is required to ensure future economical success. In today's industrial practice, die layout standards are typically assumed to implicitly ensure the balancing of company specific time-cost-quality targets. Although die layout standards are a very successful approach, there are two methodical disadvantages. First, the capabilities for tool design have to be continuously adapted to technological innovations; e.g. to take advantage of the full forming capability of new materials. Secondly, the great variety of die design aspects have to be reduced to a generic rule or guideline; e.g. binder shape, draw-in conditions or the use of drawbeads. Therefore, it is important to not overlook cost or quality opportunities when applying die design standards. This paper describes a systematic workflow with focus on minimizing material consumption. The starting point of the investigation is a full process plan for a typical structural part. All requirements are definedaccording to a predefined set of die design standards with industrial relevance are fulfilled. In a first step binder and addendum geometry is systematically checked for material saving potentials. In a second step, blank shape and draw-in are adjusted to meet thinning, wrinkling and springback targets for a minimum blank solution. Finally the identified die layout is validated with respect to production robustness versus splits, wrinkles and springback. For all three steps the applied methodology is based on finite element simulation combined with a stochastical variation of input variables. With the proposed workflow a well-balanced (time-cost-quality) production process assuring minimal material consumption can be achieved.

  4. Novel EUV mask black border and its impact on wafer imaging

    NASA Astrophysics Data System (ADS)

    Kodera, Yutaka; Fukugami, Norihito; Komizo, Toru; Watanabe, Genta; Ito, Shin; Yoshida, Itaru; Maruyama, Shingo; Kotani, Jun; Konishi, Toshio; Haraguchi, Takashi

    2016-03-01

    EUV lithography is the most promising technology for semiconductor device manufacturing of the 10nm node and beyond. The EUV mask is a key element in the lithographic scanner optical path. The image border is a pattern free dark area around the die on the photomask serving as transition area between the parts of the mask that is shielded from the exposure light by the Reticle Masking (REMA) blades and the die. When printing a die at dense spacing on an EUV scanner, the EUV light reflection from the image border overlaps edges of neighboring dies, affecting CD and contrast in this area. To reduce this effect an etched multilayer type black border was developed, and it was demonstrated that CD impact at the edge of a die is strongly reduced with this type of the black border (BB). However, wafer printing result still showed some CD change influenced by the black border reflection. It was proven that the CD shift was caused by DUV Out of Band (OOB) light which is emitted from EUV light source. New types of a multilayer etched BB were evaluated and showed a good potential for DUV light suppression. In this study, a novel black border called Hybrid Black Border has been developed which allows to eliminate EUV and DUV OOB light reflection. Direct measurements of OOB light from HBB and Normal BB are performed on NXE:3300B ASML EUV scanner; it is shown that HBB OOB reflection is 3x lower than that of Normal BB. Finally, we state that HBB is a promising technology allowing for CD control at die edges.

  5. Prognostic Value of Thyroid Hormone Levels in Patients Evaluated for Liver Transplantation

    PubMed Central

    Van Thiel, David H.; Udani, Mahendra; Schade, Robert R.; Sanghvi, Agit; Starzl, Thomas E.

    2010-01-01

    The thyroid hormones T4, T3, rT3 and TSH were assayed in 134 adult patients evaluated and accepted as potential liver transplant candidates at the University of Pittsburgh from March, 1981 to December, 1983. The subsequent course of these patients was evaluated with respect to the levels of these hormones obtained at the time of acceptance for transplantation. T4 levels were increased significantly while their T3 levels were reduced (both p < 0.01) in those who survived and were discharged home as compared to either those who died waiting to be transplanted or died following the procedure. As a result, the ratio of T3/T4 was reduced markedly (p < 0.01) in those who were transplanted and survived as compared to those not transplanted or dying following transplantation. Importantly, the rT3 levels clearly separated (p < 0.01) those who would die prior to transplantation from those who would survive to be transplanted. Finally, the ratio rT3/T3 even more clearly separates those who will die prior to transplantation (p < 0.01) from the other two groups. These data suggest that thyroid hormone levels, particularly rT3 levels, might be useful in setting priorities for which patients referred for a transplantation evaluation should be accepted into the program and in determining who among accepted patients should be operated upon in preference to others also accepted and waiting to be transplanted. PMID:2993148

  6. 76 FR 38134 - Final Priorities; Disability and Rehabilitation Research Projects and Centers Program-Disability...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-29

    ...-identified research designs to generate reliable and valid findings. Changes: None. Final Priorities Priority... DEPARTMENT OF EDUCATION Final Priorities; Disability and Rehabilitation Research Projects and Centers Program--Disability Rehabilitation Research Projects, etc. AGENCY: Office of Special Education and...

  7. Determination of total plutonium content in spent nuclear fuel assemblies with the differential die-away self-interrogation instrument

    NASA Astrophysics Data System (ADS)

    Kaplan, Alexis C.; Henzl, Vladimir; Menlove, Howard O.; Swinhoe, Martyn T.; Belian, Anthony P.; Flaska, Marek; Pozzi, Sara A.

    2014-11-01

    As a part of the Next Generation Safeguards Initiative Spent Fuel project, we simulate the response of the Differential Die-away Self-Interrogation (DDSI) instrument to determine total elemental plutonium content in an assayed spent nuclear fuel assembly (SFA). We apply recently developed concepts that relate total plutonium mass with SFA multiplication and passive neutron count rate. In this work, the multiplication of the SFA is determined from the die-away time in the early time domain of the Rossi-Alpha distributions measured directly by the DDSI instrument. We utilize MCNP to test the method against 44 pressurized water reactor SFAs from a simulated spent fuel library with a wide dynamic range of characteristic parameters such as initial enrichment, burnup, and cooling time. Under ideal conditions, discounting possible errors of a real world measurement, a root mean square agreement between true and determined total Pu mass of 2.1% is achieved.

  8. Religious affiliation at time of death - Global estimates and projections.

    PubMed

    Skirbekk, Vegard; Todd, Megan; Stonawski, Marcin

    2018-03-01

    Religious affiliation influences societal practices regarding death and dying, including palliative care, religiously acceptable health service procedures, funeral rites and beliefs about an afterlife. We aimed to estimate and project religious affiliation at the time of death globally, as this information has been lacking. We compiled data on demographic information and religious affiliation from more than 2500 surveys, registers and censuses covering 198 nations/territories. We present estimates of religious affiliation at the time of death as of 2010, projections up to and including 2060, taking into account trends in mortality, religious conversion, intergenerational transmission of religion, differential fertility, and gross migration flows, by age and sex. We find that Christianity continues to be the most common religion at death, although its share will fall from 37% to 31% of global deaths between 2010 and 2060. The share of individuals identifying as Muslim at the time of death increases from 21% to 24%. The share of religiously unaffiliated will peak at 17% in 2035 followed by a slight decline thereafter. In specific regions, such as Europe, the unaffiliated share will continue to rises from 14% to 21% throughout the period. Religious affiliation at the time of death is changing globally, with distinct regional patterns. This could affect spatial variation in healthcare and social customs relating to death and dying.

  9. Inter-organisation communication for end of life care.

    PubMed

    Thomas, Paul

    2009-01-01

    Background Poor communication between in-hours and out-of-hours (OoH) general practitioners (GPs) causes unwanted admissions to hospital of patients who want to die at home Setting A GP OoH service in West London (London Central and West Unscheduled Care Service) used by 159 general practices from four primary care trusts Question What helps to avoid hospital admission of patients who want to die at home when a crisis occurs in the OoH period? Methods Whole system participatory action research, with four stages: 1. engage stakeholders; 2. understand the initial situation; 3. re-design the system; 4. action for change Results The following help to avoid undesirable hospital admission of a dying person who has a crisis in the OoH period: 1. a register of vulnerable adults; 2. records at home; 3. key worker(s); 4. home interventions; 5. day-time practitioner communication; 6. a development and governance group; 7. speedy discharge from hospital; 8. decision support for OoH GPs. Discussion This project revealed a useful set of policies to help avoid unnecessary OoH admission to hospital, especially improved communication between day-time GPs and OoH GPs. The approach combined whole system participatory action research with systems modelling and this helped the issues to be revealed quickly and cheaply. Furthermore, including leaders from partner organisations at each stage of the inquiry has encouraged shared purpose and produced champions to move forward the project recommendations. Some changes have already happened.

  10. Reading "Terebithia" in Southern Virginia

    ERIC Educational Resources Information Center

    Baker, Dori Grinenko

    2008-01-01

    The author discusses reading "The Bridge to Terebithia" to a third-grade class prior to release of the film version. Reading of the final chapter followed by two days the April 16, 2007 shootings at Virginia Tech University, just seventy miles from the classroom. Although none of the college students from the author's town died, everyone…

  11. The compression of wood/thermoplastic fiber mats during consolidation

    Treesearch

    Karl R. Englund; Michael P. Wolcott; John C. Hermanson

    2004-01-01

    Secondary processing of non-woven wood and wood/thermoplastic fiber mats is generally performed using compression molding, where heated platens or dies form the final product. Although the study and use of wood-fiber composites is widespread, few research efforts have explicitly described the fundamentals of mat consolidation. In contrast, the wood composite literature...

  12. Large-scale drought-induced vegetation die-off: expanding the ecohydrological emphasis more explicitly on atmospheric demand. (Invited)

    NASA Astrophysics Data System (ADS)

    Breshears, D. D.; Adams, H. D.; Eamus, D.; McDowell, N. G.; Law, D. J.; Will, R. E.; Williams, P.; Zou, C.

    2013-12-01

    Ecohydrology focuses on the interactions of water availability, ecosystem productivity, and biogeochemical cycles via ecological-hydrological connections. These connections can be particularly pronounced and socially relevant when there are large-scale rapid changes in vegetation. One such key change, vegetation mortality, can be triggered by drought and is projected to become more frequent and/or extensive in the future under changing climate. Recent research on drought-induced vegetation die-off has focused primarily on direct drought effects, such as soil moisture deficit, and, to a much lesser degree, the potential for warmer temperatures to exacerbate stress and accelerate mortality. However, temperature is tightly interrelated with atmospheric demand (vapor pressure deficit, VPD) but the latter has rarely been considered explicitly relative to die-off events. Here we highlight the importance of VPD in addition to soil moisture deficit and warmer temperature as an important driver of future die-off. Recent examples highlighting the importance of VPD include mortality patterns corresponding to VPD drivers, a strong dependence of forest growth on VPD, patterns of observed mortality along an environmental gradient, an experimentally-determined climate envelope for mortality, and a suite of modeling simulations segregating the drought effects of VPD from those of temperature. The vast bulk of evidence suggests that atmospheric demand needs to be considered in addition to temperature and soil moisture deficit in predicting risk of future vegetation die-off and associated ecohydrological transformations.

  13. Causes and circumstances of death in pulmonary arterial hypertension.

    PubMed

    Tonelli, Adriano R; Arelli, Vineesha; Minai, Omar A; Newman, Jennie; Bair, Nancy; Heresi, Gustavo A; Dweik, Raed A

    2013-08-01

    The causes and circumstances surrounding death are understudied in patients with pulmonary arterial hypertension (PAH). We sought to determine the specific reasons and characteristics surrounding the death of patients with PAH. All deaths of patients with pulmonary hypertension (PH) followed in the Cleveland Clinic Pulmonary Vascular Program were prospectively reviewed by the PH team. A total of 84 patients with PAH (age 58 ± 14 yr; 73% females) who died between June 2008 and May 2012 were included. PH was determined to be the direct cause of death (right heart failure or sudden death) in 37 (44%) patients; PH contributed to but did not directly cause death in 37 (44%) patients; and the death was not related to PH in the remaining cases (n = 7; 8.3%). In three (3.6%) patients the final cause of death could not be adequately assessed. Most patients died in a healthcare environment and most received PH-specific therapies. In our cohort, 50% of all patients with PAH and 75.7% of those who died of right heart failure received parenteral prostanoid therapy. Less than half of patients had advanced healthcare directives. Most patients with PAH in our cohort died of their disease; however, right ventricular failure or sudden death was the sole cause of death in less than half of patients.

  14. Characterizing the Elastic Behaviour of a Press Table through Topology Optimization

    NASA Astrophysics Data System (ADS)

    Pilthammar, J.; Sigvant, M.; Hansson, M.; Pálsson, E.; Rutgersson, W.

    2017-09-01

    Sheet metal forming in the car industry is a highly competitive area. The use of digital techniques and numerical methods are therefore of high interest for reduced costs and lead times. One method for reducing the try-out phase is virtual rework of die surfaces. The virtual rework is based on Finite Element (FE) simulations and can reduce and support manual rework. The elastic behaviour of dies and presses must be represented in a reliable way in FE-models to be able to perform virtual rework. CAD-models exists for nearly all dies today, but not for press lines. A full geometrical representation of presses will also yield very large FE- models. This paper will discuss and demonstrate a strategy for measuring and characterizing a press table for inclusion in FE-models. The measurements of the elastic press deformations is carried out with force transducers and an ARAMIS 3D optical measurement system. The press table is then inverse modelled by topology optimization using the recorded results as boundary conditions. Finally, the press table is coupled with a FE-model of a die to demonstrate its influence on the deformations. This indicates the importance of having a reliable representation of the press deformations during virtual rework.

  15. Mechanical Engineering Senior Design Project Final Presentations | College

    Science.gov Websites

    Mechanical Engineering Senior Design Project Final Presentations December 7, 2015 Mechanical Engineering On Wednesday, Dec. 9th, the mechanical engineering senior design project final presentations will be made in and Steven Keller Objective: Design a temperature controlled unit that would cool and maintain a

  16. 76 FR 56973 - Office of National Marine Sanctuaries Final Policy and Permit Guidance for Submarine Cable Projects

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-15

    ... National Marine Sanctuaries Final Policy and Permit Guidance for Submarine Cable Projects AGENCY: Office of National Marine Sanctuaries (ONMS), National Oceanic and Atmospheric Administration (NOAA), Department of... Marine Sanctuaries (ONMS) has developed final policy and permitting guidance for submarine cable projects...

  17. Description of the supporting factors of final project in Mathematics and Natural Sciences Faculty of Syiah Kuala University with multiple correspondence analysis

    NASA Astrophysics Data System (ADS)

    Rusyana, Asep; Nurhasanah; Maulizasari

    2018-05-01

    Syiah Kuala University (Unsyiah) is hoped to have graduates who are qualified for working or creating a field of work. A final project course implementation process must be effective. This research uses data from the evaluation conducted by Mathematics and Natural Sciences Faculty (FMIPA) of Unsyiah. Some of the factors that support the completion of the final project are duration, guidance, the final project seminars, facility, public impact, and quality. This research aims to know the factors that have a relationship with the completion of the final project and identify similarities among variables. The factors that support the completion of the final project at every study program in FMIPA are (1) duration, (2) guidance and (3) facilities. These factors are examined for the correlations by chi-square test. After that, the variables are analyzed with multiple correspondence analysis. Based on the plot of correspondence, the activities of the guidance and facilities in Informatics Study Program are included in the fair category, while the guidance and facilities in the Chemistry are included in the best category. Besides that, students in Physics can finish the final project with the fastest completion duration, while students in Pharmacy finish for the longest time.

  18. Effects of capture-related injury on postcapture movement of white-tailed deer.

    PubMed

    Dechen Quinn, Amy C; Williams, David M; Porter, William F; Fitzgerald, Scott D; Hynes, Kevin

    2014-04-01

    Capture-related injuries or deaths of wildlife study subjects pose concerns to researchers, from considerations for animal welfare to inflated project costs and biased data. Capture myopathy (CM) is an injury that can affect an animal's survival ≤ 30 days postrelease, but is often difficult to detect without close monitoring and immediate necropsy. We evaluated the influence of capture and handling on postcapture movement in an attempt to characterize movement rates of animals suffering from CM. We captured and global positioning system-collared 95 white-tailed deer (Odocoileus virginianus) in central and northern New York during 2006-2008. Six juveniles died within 30 days postrelease, and necropsy reports indicated that two suffered CM (2%). We compared postcapture movement rates for juveniles that survived >30 days with those that died ≤ 30 days postcapture. Survivor movement rates (43.74 m/hr, SD = 3.53, n = 28) were significantly higher than rates for deer that died within 30 days (17.70 m/hr, SD = 1.57, n = 6) (P<0.01). Additionally, movement rates of juveniles that died of CM (15.1 m/hr) were 5.1 m/hr lower than those for juveniles that died of other causes ≤ 30 days postcapture (20.2 m/hr), but we were unable to evaluate this statistically because of insufficient sample size. We found no difference in vital rates (temperature, heart rate, respiration rate) during handling between survivors and juveniles that died within 30 days postcapture but observed that survivors were in better body condition at capture. These results suggest that deer likely to die within the 30-day CM window can be identified soon after capture, provided that intensive movement data are collected. Further, even if necropsy reports are unavailable, these animals should be censored from analysis because their behavior is not representative of movements of surviving animals.

  19. The potential therapeutic value for bereaved relatives participating in research: An exploratory study.

    PubMed

    Germain, Alison; Mayland, Catriona R; Jack, Barbara A

    2016-10-01

    Conducting research with the bereaved presents an immediate ethical challenge, as they are undoubtedly a vulnerable group, associated with high levels of distress and susceptible to both physical and mental health issues. A comprehensive understanding of the potential therapeutic benefits for bereaved relatives participating in palliative care research is limited, and therefore the ethics of engaging this group remain questionable. This paper describes a secondary analysis of qualitative data collected in the Care of the Dying Evaluation (CODE) project, examining the experiences of patients who died at home. It explores the motivations and potential benefits for bereaved relatives participating in research with reference to the recently developed concepts in bereavement theory. Cognitive interviews were conducted with 15 bereaved relatives and secondary analysis using a content analysis framework was employed to classify the data. The results center around six recurring concepts identified as adaptive in current bereavement theory: an opportunity to share the narrative accounts of the final hours of their relative's life; a search for sense and meaning in loss; an ongoing bond/attachment with the deceased; altruistic motivations; oscillation between loss and restorative orientations; and a sense of resilience. Overall, the participants found that taking part in the research was valuable and that it could be described as offering therapeutic benefits. The need for bereaved relatives to take part in research studies should be encouraged, as they provide an accurate proxy for the patient's experience of end-of-life care while also providing a valuable account of their own perspective as family member and carer. In addition, we highlight the need for ethics committees to be aware of the potential benefits for bereaved relatives participating in research of this kind.

  20. 36 CFR 64.14 - Project inspections.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 36 Parks, Forests, and Public Property 1 2010-07-01 2010-07-01 false Project inspections. 64.14... Project inspections. All State and local projects will receive a final inspection by the Bureau. Final... as deemed necessary by the Bureau. Preapproval inspections will also be conducted prior to project...

  1. 36 CFR 64.14 - Project inspections.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 36 Parks, Forests, and Public Property 1 2014-07-01 2014-07-01 false Project inspections. 64.14... Project inspections. All State and local projects will receive a final inspection by the Bureau. Final... as deemed necessary by the Bureau. Preapproval inspections will also be conducted prior to project...

  2. 36 CFR 64.14 - Project inspections.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 36 Parks, Forests, and Public Property 1 2011-07-01 2011-07-01 false Project inspections. 64.14... Project inspections. All State and local projects will receive a final inspection by the Bureau. Final... as deemed necessary by the Bureau. Preapproval inspections will also be conducted prior to project...

  3. 36 CFR 64.14 - Project inspections.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 36 Parks, Forests, and Public Property 1 2012-07-01 2012-07-01 false Project inspections. 64.14... Project inspections. All State and local projects will receive a final inspection by the Bureau. Final... as deemed necessary by the Bureau. Preapproval inspections will also be conducted prior to project...

  4. Program Evaluation - Automotive Lightweighting Materials Program Research and Development Projects Assessment of Benefits - Case Studies No. 2

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Das, S.

    This report is the second of a series of studies to evaluate research and development (R&D) projects funded by the Automotive Lightweighting Materials (ALM) Program of the Office of Advanced Automotive Technologies (OAAT) of the U.S. Department of Energy (DOE). The objectives of the program evaluation are to assess short-run outputs and long-run outcomes that may be attributable to the ALM R&D projects. The ALM program focuses on the development and validation of advanced technologies that significantly reduce automotive vehicle body and chassis weight without compromising other attributes such as safety, performance, recyclability, and cost. Funded projects range from fundamentalmore » materials science research to applied research in production environments. Collaborators on these projects include national laboratories, universities, and private sector firms, such as leading automobile manufacturers and their suppliers. Three ALM R&D projects were chosen for this evaluation: Design and Product Optimization for Cast Light Metals, Durability of Lightweight Composite Structures, and Rapid Tooling for Functional Prototyping of Metal Mold Processes. These projects were chosen because they have already been completed. The first project resulted in development of a comprehensive cast light metal property database, an automotive application design guide, computerized predictive models, process monitoring sensors, and quality assurance methods. The second project, the durability of lightweight composite structures, produced durability-based design criteria documents, predictive models for creep deformation, and minimum test requirements and suggested test methods for establishing durability properties and characteristics of random glass-fiber composites for automotive structural composites. The durability project supported Focal Project II, a validation activity that demonstrates ALM program goals and reduces the lead time for bringing new technology into the marketplace. Focal projects concentrate on specific classes of materials and nonproprietary components and are done jointly by DOE and the Automotive Composites Consortium of U.S. Council for Automotive Research (USCAR). The third project developed a rapid tooling process that reduces tooling time, originally some 48-52 weeks, to less than 12 weeks by means of rapid generation of die-casting die inserts and development of generic holding blocks, suitable for use with large casting applications. This project was conducted by the United States Automotive Materials Partnership, another USCAR consortium.« less

  5. Novel EUV mask black border suppressing EUV and DUV OoB light reflection

    NASA Astrophysics Data System (ADS)

    Ito, Shin; Kodera, Yutaka; Fukugami, Norihito; Komizo, Toru; Maruyama, Shingo; Watanabe, Genta; Yoshida, Itaru; Kotani, Jun; Konishi, Toshio; Haraguchi, Takashi

    2016-05-01

    EUV lithography is the most promising technology for semiconductor device manufacturing of the 10nm node and beyond. The image border is a pattern free dark area around the die on the photomask serving as transition area between the parts of the mask that is shielded from the exposure light by the Reticle Masking (REMA) blades and the die. When printing a die at dense spacing on an EUV scanner, the reflection from the image border overlaps edges of neighboring dies, affecting CD and contrast in this area. This is related to the fact that EUV absorber stack reflects 1-3% of actinic EUV light. To reduce this effect several types of image border with reduced EUV reflectance (<0.05%) have been proposed; such an image border is referred to as a black border. In particular, an etched multilayer type black border was developed; it was demonstrated that CD impact at the edge of a die is strongly reduced with this type of the black border (BB). However, wafer printing result still showed some CD change in the die influenced by the black border reflection. It was proven that the CD shift was caused by DUV Out of Band (OOB) light from the EUV light source. New types of a multilayer etched BB were evaluated and showed a good potential for DUV light suppression. In this study, a novel BB called `Hybrid Black Border' (HBB) has been developed to eliminate EUV and DUV OOB light reflection by applying optical design technique and special micro-fabrication technique. A new test mask with HBB is fabricated without any degradation of mask quality according to the result of CD performance in the main pattern, defectivity and cleaning durability. The imaging performance for N10 imaging structures is demonstrated on NXE:3300B in collaboration with ASML. This result is compared to the imaging results obtained for a mask with the earlier developed BB, and HBB has achieved ~3x improvement; less than 0.2 nm CD changes are observed in the corners of the die. A CD uniformity budget including impact of OOB light in the die edge area is evaluated which shows that the OOB impact from HBB becomes comparable with other CDU contributors in this area. Finally, we state that HBB is a promising technology allowing for CD control at die edges.

  6. Final Project Report for Award ER65581

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Stoy, Paul C.

    2017-07-13

    The attached final project report describes contributions of Montana State University (MSU) to the project "Bridging land-surface fluxes and aerosol concentrations to triggering convective rainfall" (PI: Fuentes).

  7. Georgia Deaf-Blind Pilot Project: Project EPIC. Final Report. Optional Pilot Projects for Children with Deaf-Blindness.

    ERIC Educational Resources Information Center

    Georgia State Dept. of Education, Atlanta.

    This final report describes activities and accomplishments of Project EPIC (Effective Partner Interaction in the Community), a 3-year federally supported project in Georgia to facilitate the establishment and implementation of effective educational practices with students having deaf-blindness. The project was designed to expand students' present…

  8. Picking a Hill to Die On: Discreet Activism, Leadership and Social Justice in Education

    ERIC Educational Resources Information Center

    Ryan, James; Tuters, Stephanie

    2017-01-01

    Purpose: The purpose of this paper is to describe a study that explores the discreet activist strategies of educational leaders who promote social justice. Design/methodology/approach: Part of a larger project, this study employed qualitative methods. In particular, researchers interviewed 26 leaders--principals, vice principals, department heads,…

  9. Early estimate of motor vehicle traffic fatalities for the first quarter (January-March) of 2009 : a brief statistical summary

    DOT National Transportation Integrated Search

    2009-06-01

    A statistical projection of traffic fatalities for the first quarter of 2009 shows that an estimated 7,689 people died in motor vehicle traffic crashes. This represents a decline of about 9 percent as compared to the 8,451 fatalities that occurred in...

  10. Circling "the Scourge"

    ERIC Educational Resources Information Center

    Keller, Bess

    2005-01-01

    In Kenya alone, where the infection rate is estimated to have reached 13 percent of the population, 27,000 teachers will die and more than 2 million children will lose one or both parents to AIDS in the next five years. The Kenyan project uses "study circles," in which teachers learn together about HIV, script new sexual behaviors for…

  11. The Right to Live and Die. Canadian Critical Issues Series.

    ERIC Educational Resources Information Center

    Eisenberg, John; Bourne, Paula

    One of a series adapted from the Canadian Public Issues Project, this book is designed to stimulate discussion and reflection about controversial issues through case studies. The book is based on high school units originally drawn from cases in newspapers, journals, books, legal documents, and government reports. Conflicts from issues arising over…

  12. Early estimate of motor vehicle traffic fatalities for the first half (January-June) of 2010 : a brief statistical summary

    DOT National Transportation Integrated Search

    2010-09-01

    A statistical projection of traffic fatalities for the first half of : 2010 shows that an estimated 14,996 people died in motor : vehicle traffic crashes. This represents a decline of about 9.2 : percent as compared to the 16,509 fatalities that occu...

  13. BJORN HAAVARD WIIK: The man and his accelerator projects

    NASA Astrophysics Data System (ADS)

    Johnsen, Kjell

    2001-04-01

    Björn Haavard Wiik died in an accident on 26th February, 1999. The high-energy community lost an outstanding scientist, DESY lost a highly appreciated and widely respected director, a closely knit family lost a husband, a father and a son and many of us lost an extraordinary friend...

  14. Biological assessment for the transfer of the DP land tract

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Keller, D.C.

    1996-10-01

    The Department of Energy (DOE) is proposing to transfer to the County of Los Alamos up to 10-ha (25-ac) of federal land located in Technical Area-21 to be developed for commercial uses. Previous studies for the proposed land transfer area indicate that potential habitat for four threatened, endangered, and sensitive species occurs in or adjacent to the proposed land transfer area. These include the northern goshawk (federal species of concern), Mexican spotted owl (federal threatened), the spotted bat (federal species of concern, state threatened), die peregrine falcon (federal endangered, state endangered), and the. In order to determine the possible influencesmore » of the land transfer on these organisms, information from species-specific surveys was collected. These surveys were used to confirm the presence of these species or to infer their absence in or near the project area. It was concluded that none of die above mentioned species occur in the project area. Stretches of the stream channel within Los Alamos Canyon have been identified as palustrine and riverine, temporarily flooded wetlands. The proposed land transfer should not affect these wetlands.« less

  15. The European mesothelioma epidemic.

    PubMed

    Peto, J; Decarli, A; La Vecchia, C; Levi, F; Negri, E

    1999-02-01

    Projections for the period 1995-2029 suggest that the number of men dying from mesothelioma in Western Europe each year will almost double over the next 20 years, from 5000 in 1998 to about 9000 around 2018, and then decline, with a total of about a quarter of a million deaths over the next 35 years. The highest risk will be suffered by men born around 1945-50, of whom about 1 in 150 will die of mesothelioma. Asbestos use in Western Europe remained high until 1980, and substantial quantities are still used in several European countries. These projections are based on the fit of a simple age and birth cohort model to male pleural cancer mortality from 1970 to 1989 for six countries (Britain, France, Germany, Italy, The Netherlands and Switzerland) which together account for three-quarters of the population of Western Europe. The model was tested by comparing observed and predicted numbers of deaths for the period 1990-94. The ratio of mesothelioma to recorded pleural cancer mortality has been 1.6:1 in Britain but was assumed to be 1:1 in other countries.

  16. 77 FR 67662 - Notice of Availability of the Desert Harvest Solar Project Final Environmental Impact Statement...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-13

    ... decommission a solar photovoltaic electricity generating facility with a proposed output of 150 megawatts and a... CACA 49491] Notice of Availability of the Desert Harvest Solar Project Final Environmental Impact...) Plan Amendment and Final Environmental Impact Statement (EIS) for the Desert Harvest Solar Project and...

  17. Rural Textile Workers Literacy Enhancement Project. Final Performance Report.

    ERIC Educational Resources Information Center

    Enterprise State Junior Coll., AL.

    This document consists of the final report and sample curricula from the Rural Textile Workers Literacy Enhancement Project. The final report details how the project was initiated in April 1993 to help employees of five textile and apparel manufacturing companies in southeastern Alabama improve their literacy and numeracy skills. A second…

  18. 77 FR 30514 - Native Hawaiian Career and Technical Education Program; Final Waiver and Extension of Project Period

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-23

    ... DEPARTMENT OF EDUCATION Native Hawaiian Career and Technical Education Program; Final Waiver and.... ACTION: Notice. Overview Information Final Waiver and Extension of Project Period for the Native Hawaiian.... SUMMARY: For 36-month projects funded in fiscal year (FY) 2009 under the Native Hawaiian Career and...

  19. Large Area Silicon Sheet by EFG

    NASA Technical Reports Server (NTRS)

    Wald, F. V.

    1979-01-01

    Displaced die concepts were explored along with some initial work on buckle characterization. Convective impurity redistribution was further studied. Growth from single cartridges was continued to create a quality baseline to allow comparison of the results with those in the upcoming multiple run and to choose the most appropriate die design. Fabrication and assembly work on the actual five ribbon furnace continued. Progress was made toward the development of the video optical system for edge position and meniscus height control. In preparation for a detailed program, designed to explore the buckling problem, ribbon guidance in the machine was improved. Buckle free, full width ribbon was grown under stable conditions without a cold shoe, an achievement essential to finally arrive at quantitative correlations between growth conditions and buckle formation.

  20. Rapid variability, dying pulse trains and black holes

    NASA Technical Reports Server (NTRS)

    Stoeger, W. R.

    1980-01-01

    After reviewing the general model and arguments by which rapid temporal variability and quasi-periodicities are considered indicative of a compact source's possible black hole character, the paper presents a scenario for 'dying pulse trains'. These originate inside the inner edge of accretion disks encircling black holes from accreting flares or other self-luminous entities executing their final few revolutions before reaching the event horizon. Confirmed detection of such phenomena with time scales in the range 0.01 (M/solar mass) to 0.5 (M/solar mass)ms, where M is the mass of the compact source, would provide much better support for its black hole candidacy. Variability on time-scales larger than this by itself places few constraints on the nature of the compact object.

  1. Hawaii Demonstration Project to Avert Unintended Teenage Pregnancy: 1978-1982. Final Report. Executive Summary.

    ERIC Educational Resources Information Center

    Levitt-Merin, Marta; Sutter, Sharon Kingdon

    This final report provides a descriptive overview of three approaches which the Hawaii Demonstration Project initiated to reduce unintended teenage pregnancies. Project evaluation findings are summarized; both qualitative and quantitative data are presented for a comprehensive picture of the project and its input. Project limitations and successes…

  2. 78 FR 57264 - Final Waiver and Extension of the Project Period for the Technical Assistance Coordination Center

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-18

    ...: 84.326Z.] Final Waiver and Extension of the Project Period for the Technical Assistance Coordination... project period. SUMMARY: The Secretary waives the requirements in the Education Department General Administrative Regulations that generally prohibit project periods exceeding five years and extensions of project...

  3. NCAP projection displays

    NASA Astrophysics Data System (ADS)

    Havens, John R.; Ishioka, J.; Jones, Philip J.; Lau, Aldrich; Tomita, Akira; Asano, A.; Konuma, Nobuhiro; Sato, Kazuhiko; Takemoto, Iwao

    1997-05-01

    Projectors based on polymer-eNCAPsulated liquid crystals can provide bright displays suitable for use in conference rooms with normal lighting. Contrast is generated by light scattering among the droplets, rather than by light absorption with crossed polarizers. We have demonstrated a full-color, compact projector showing 1200 ANSI lumens with 200 watts of lamp power - a light efficiency of 6 lumens/watt. This projector is based on low-voltage NCAP material, highly reflective CMOS die, and matched illumination and projection optics. We will review each of these areas and discuss the integrated system performance.

  4. Elucidation of Inflammation Processes Exacerbating Neuronal Cell Damage to the Retina and Brain Visual Centers as Quest for Therapeutic Drug Targets in Rat Model of Blast Overpressure Wave Exposure

    DTIC Science & Technology

    2016-10-01

    Righting Reflex of rats following double blast exposure. 0 4 8 12 16 20 R ig ht in g Re fle x (m in ut es ) PLACEBO FISH OIL Total Lived Died...experiments. Funding Support: Geneva Foundation contractor – WRAIR Name: Joseph B. Long, Ph.D. Project Role: Co-Investigator – WRAIR Researcher...Funding Support: Clinical Research Management contractor Name: Andrew B. Batuure Project Role: Technician - WRAIR Researcher Identifier (e.g. ORCID

  5. Facing Finality: Cognitive and Cultural Studies on Death and Dying "Arabic Culture"

    ERIC Educational Resources Information Center

    Al-Meshhedany, Amna A. Hasan; Al-Sammerai, Nabiha S. Mehdi

    2010-01-01

    Semantics is a study of human beings cultural background, has from its beginning as a field of study been concerned with the study of humans understanding of culture. Understanding the meaning of "death" has been of great importance to many of the central theoretical developments in this field, especially as it imposes on studies of…

  6. How the Arabellion Affects the Strength of Egypt as a Nation State

    DTIC Science & Technology

    2014-12-12

    entzündet und letztlich die ganze arabische Welt verändert hat.” [His act was the spark that ignited the fire and that finally changed the whole Arab...preliminary conclusion highlights two major patterns that run like a common thread through the recent history of Egypt. A Rule Based on the Division of

  7. Recent Developments in Polymeric Charge Transfer Complexes

    DTIC Science & Technology

    1994-03-01

    systems using dies on nematic phases of polymers involhing p- the Langmuir Blodgett procedure to obtain multi- chiloranil as the acceptor molecule [8...excluded. These applications are: compatibilization of polymer blends, liquid crystalline supramolecular organization, new develoments in...polymner blends, liquid crystalline supra- technological developments. Finally, I will cover in nmlecular organization, ne,’, developments in photo- some

  8. "We're All Gonna' Die": Using Human Interest in Disasters to Promote Student Interest and Research in Introductory Science Classes for Non-Science Majors.

    NASA Astrophysics Data System (ADS)

    Prueher, L.

    2008-12-01

    Humans are fascinated by disasters. Volcanic eruptions, earthquakes, and other natural disasters capture the public interest and provide educators a venue in which to present scientific information and dispel common misconceptions. Presenting scientific information via the vehicle of a disaster can attract even the most science-phobic student, capturing their interest in a way that more traditional methods of presentation cannot or do not. People are inundated with scientific data through the popular media yet little is done to provide non-scientists with the information needed to distinguish between fact and fiction. Docudramas such as, "Supervolcano", blur the boundary between reality and fiction. Human interest in disasters can be used as an educational tool to foster scientific literacy among non-science majors. "We're All Gonna' Die", is an inquiry-based research project used in introductory geology classes at Arapahoe Community College and the University of Northern Colorado. Most students taking this class have no college science background. The project introduces students to geological and environmental hazards. Students choose a city of interest, analyze the potential geologic and environmental hazards in the area, and determine what can be done to minimize potential damage and fatalities. Students are more interested in a topic and delve deeper into the subject matter when researching a project of their own choosing. Students have incorporated demonstrations, skits, student-made videos, games, current geologic events, and research results into their projects. Perhaps as important, the students have fun, become excited about their project and topic, and disseminate the information to family and friends.

  9. End-of-life care of children with diffuse intrinsic pontine glioma.

    PubMed

    Hasan, Fyeza; Weingarten, Kevin; Rapoport, Adam; Bouffet, Eric; Bartels, Ute

    2018-05-01

    The end-of-life management of children with diffuse intrinsic pontine glioma (DIPG) is challenging. Families cope with debilitating symptoms and make complex decisions regarding their child's care. However, there is little evidence guiding palliative care provision for these children. Our objective was to describe the dying trajectory of children with DIPG, their symptoms, the care they require and the end-of-life decisions made for them. This retrospective cohort study analyzed the end-of-life care of 41 consecutive patients with DIPG who died between January 2001 and June 2010. All patients died of disease progression, experiencing a significant symptom burden prior to death. Despite this, the majority of patient days at the end of life were spent at home. However, 60% of patients were hospitalized at least once in their final 3 months, often close to the time of death. A wide range of healthcare professionals were involved, providing a range of medicinal/non-medicinal interventions. Chemotherapy was given to 30% of patients in their final month. Thirty of 33 families approached (91%) agreed to a "Do not resuscitate" order. A small subset of families opted for intensive treatment towards the end of life including cardiopulmonary resuscitation, intensive care admission and mechanical ventilation. Children with DIPG have complex needs and require intensive multidisciplinary support. This paper describes the end-of-life choices made for these children and discusses how these choices influence our institutional model for palliative care. We believe this approach will be useful to clinicians caring for similar patients.

  10. Materials to Prepare Hospice Families for Dying in the Home

    PubMed Central

    Kirchhoff, Karin T.; Finster, Mark P.; Cleary, James F.

    2008-01-01

    Abstract Many changes occur in the final hours of life. Family members of those dying at home need to be prepared for these changes, both to understand what is happening and to provide care. The objectives of this study were to describe (1) the written materials used by hospices to prepare families for dying in the home setting and (2) the content of such materials. Questionnaires were sent to 400 randomly selected hospices, of which 170 responded (45.3%) sending their written materials. The most frequently used publications were Gone from My Sight (n = 118 or 69.4%), Final Gifts (n = 44 or 25.9%) and Caregiving (n = 14 or 8.2%). Half (56.5%) of the hospices used other publications and a majority (n = 87 or 51.2%) used multiple publications. Materials were given to the families by nurses (78.2%) or social workers (67.6%). More than 90% of the hospices had materials that addressed the following signs of impending death: decreased fluid intake, decreased food intake, breathing pattern changes, cold extremities, mottling, increased sleeping, changes at the moment of death, audible secretions, urinary output changes, disorientation, incontinence, overall decline and restlessness. Seven signs were addressed less than 30% of the time; pain (28.2%), dyspnea (19.4%), bed-bound state (18.2%), skin changes (18.2%), vital sign changes (17.1%), surge of energy (11.8%) and mandibular breathing (5.9%). Hospice staff should know the content of the materials offered by their agency so they can verbally address the gaps between the written materials and family needs. PMID:18788956

  11. Materials to prepare hospice families for dying in the home.

    PubMed

    Kehl, Karen A; Kirchhoff, Karin T; Finster, Mark P; Cleary, James F

    2008-09-01

    Many changes occur in the final hours of life. Family members of those dying at home need to be prepared for these changes, both to understand what is happening and to provide care. The objectives of this study were to describe (1) the written materials used by hospices to prepare families for dying in the home setting and (2) the content of such materials. Questionnaires were sent to 400 randomly selected hospices, of which 170 responded (45.3%) sending their written materials. The most frequently used publications were Gone from My Sight (n = 118 or 69.4%), Final Gifts (n = 44 or 25.9%) and Caregiving (n = 14 or 8.2%). Half (56.5%) of the hospices used other publications and a majority (n = 87 or 51.2%) used multiple publications. Materials were given to the families by nurses (78.2%) or social workers (67.6%). More than 90% of the hospices had materials that addressed the following signs of impending death: decreased fluid intake, decreased food intake, breathing pattern changes, cold extremities, mottling, increased sleeping, changes at the moment of death, audible secretions, urinary output changes, disorientation, incontinence, overall decline and restlessness. Seven signs were addressed less than 30% of the time; pain (28.2%), dyspnea (19.4%), bed-bound state (18.2%), skin changes (18.2%), vital sign changes (17.1%), surge of energy (11.8%) and mandibular breathing (5.9%). Hospice staff should know the content of the materials offered by their agency so they can verbally address the gaps between the written materials and family needs.

  12. Nabisco Foods Division--"New Indy" Workplace Literacy Project. Final Performance Report.

    ERIC Educational Resources Information Center

    Ivy Tech State Coll., Indianapolis, IN.

    This document contains a final report, evaluation, and curriculum materials from a project conducted at the RJR Nabisco plant in Indianapolis to upgrade the literacy and numeracy skills of the workers to facilitate technological changes to production lines. As the final report explains, although the goal of the project was to recruit and test 150…

  13. Final Design Report for the RH LLW Disposal Facility (RDF) Project

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Austad, Stephanie Lee

    2015-09-01

    The RH LLW Disposal Facility (RDF) Project was designed by AREVA Federal Services (AFS) and the design process was managed by Battelle Energy Alliance (BEA) for the Department of Energy (DOE). The final design report for the RH LLW Disposal Facility Project is a compilation of the documents and deliverables included in the facility final design.

  14. Final Design Report for the RH LLW Disposal Facility (RDF) Project

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Austad, S. L.

    2015-05-01

    The RH LLW Disposal Facility (RDF) Project was designed by AREVA Federal Services (AFS) and the design process was managed by Battelle Energy Alliance (BEA) for the Department of Energy (DOE). The final design report for the RH LLW Disposal Facility Project is a compilation of the documents and deliverables included in the facility final design.

  15. Using Insider Research in MEd Final Projects to Bridge the Theory/Practice Gap

    ERIC Educational Resources Information Center

    Arar, Khalid

    2018-01-01

    This paper aims to identify key issues involved in MEd final project supervision and to highlight the potential of supervision from an academic institution to change educational reality through the postgraduate student-teachers' work-based final project as insider researchers in Israeli schools. It draws on analysis of case-study data from two…

  16. Field results from a new die-to-database reticle inspection platform

    NASA Astrophysics Data System (ADS)

    Broadbent, William; Yokoyama, Ichiro; Yu, Paul; Seki, Kazunori; Nomura, Ryohei; Schmalfuss, Heiko; Heumann, Jan; Sier, Jean-Paul

    2007-05-01

    A new die-to-database high-resolution reticle defect inspection platform, TeraScanHR, has been developed for advanced production use with the 45nm logic node, and extendable for development use with the 32nm node (also the comparable memory nodes). These nodes will use predominantly ArF immersion lithography although EUV may also be used. According to recent surveys, the predominant reticle types for the 45nm node are 6% simple tri-tone and COG. Other advanced reticle types may also be used for these nodes including: dark field alternating, Mask Enhancer, complex tri-tone, high transmission, CPL, etc. Finally, aggressive model based OPC will typically be used which will include many small structures such as jogs, serifs, and SRAF (sub-resolution assist features) with accompanying very small gaps between adjacent structures. The current generation of inspection systems is inadequate to meet these requirements. The architecture and performance of the new TeraScanHR reticle inspection platform is described. This new platform is designed to inspect the aforementioned reticle types in die-to-database and die-to-die modes using both transmitted and reflected illumination. Recent results from field testing at two of the three beta sites are shown (Toppan Printing in Japan and the Advanced Mask Technology Center in Germany). The results include applicable programmed defect test reticles and advanced 45nm product reticles (also comparable memory reticles). The results show high sensitivity and low false detections being achieved. The platform can also be configured for the current 65nm, 90nm, and 130nm nodes.

  17. Discussing end-of-life issues with terminally ill cancer patients and their carers: a qualitative study.

    PubMed

    Clayton, Josephine M; Butow, Phyllis N; Arnold, Robert M; Tattersall, Martin H N

    2005-08-01

    Discussing end-of-life issues is of key importance to terminally ill cancer patients and their families, and a challenging topic for both health professionals and patients/carers. There is a lack of research evidence in the literature to guide clinical practice. The objective of this study was to explore the optimal content and phrasing of information when discussing the dying process and end-of-life issues with terminally ill cancer patients and their carers. We conducted focus groups and individual interviews with 19 palliative care patients and 24 carers from three palliative care services in Sydney, and 22 palliative care health professionals from around Australia. The focus groups and individual interviews were audiotaped and fully transcribed. Further focus groups and/or individual interviews were conducted until no additional topics were raised. Participants' narratives were analysed using qualitative methodology. Distinct content areas emerged for discussing end-of-life issues: treatment decisions at the end-of-life; potential future symptoms; preferences for place of death; the process of dying; what needs to be done immediately after death; and existential issues. When discussing the process of dying participants recommended: exploring the persons' fears about dying and dispelling myths; describing the final days and the likely unconscious period; and the reduced need for food and fluids. Many participants identified the dilemma regarding whether to discuss potential complications around the time of death. This paper provides strategies, words and phrases which may inform discussions about the process of dying and end-of-life issues. Further research is needed to determine the generalizability of these findings.

  18. Hypoxia treatment reverses neurodegenerative disease in a mouse model of Leigh syndrome

    PubMed Central

    Ferrari, Michele; Jain, Isha H.; Goldberger, Olga; Rezoagli, Emanuele; Thoonen, Robrecht; Cheng, Kai-Hung; Sosnovik, David E.; Scherrer-Crosbie, Marielle; Mootha, Vamsi K.; Zapol, Warren M.

    2017-01-01

    The most common pediatric mitochondrial disease is Leigh syndrome, an episodic, subacute neurodegeneration that can lead to death within the first few years of life, for which there are no proven general therapies. Mice lacking the complex I subunit, Ndufs4, develop a fatal progressive encephalopathy resembling Leigh syndrome and die at ≈60 d of age. We previously reported that continuously breathing normobaric 11% O2 from an early age prevents neurological disease and dramatically improves survival in these mice. Here, we report three advances. First, we report updated survival curves and organ pathology in Ndufs4 KO mice exposed to hypoxia or hyperoxia. Whereas normoxia-treated KO mice die from neurodegeneration at about 60 d, hypoxia-treated mice eventually die at about 270 d, likely from cardiac disease, and hyperoxia-treated mice die within days from acute pulmonary edema. Second, we report that more conservative hypoxia regimens, such as continuous normobaric 17% O2 or intermittent hypoxia, are ineffective in preventing neuropathology. Finally, we show that breathing normobaric 11% O2 in mice with late-stage encephalopathy reverses their established neurological disease, evidenced by improved behavior, circulating disease biomarkers, and survival rates. Importantly, the pathognomonic MRI brain lesions and neurohistopathologic findings are reversed after 4 wk of hypoxia. Upon return to normoxia, Ndufs4 KO mice die within days. Future work is required to determine if hypoxia can be used to prevent and reverse neurodegeneration in other animal models, and to determine if it can be provided in a safe and practical manner to allow in-hospital human therapeutic trials. PMID:28483998

  19. Learning About Dying and Living: An Applied Approach to End-of-Life Communication.

    PubMed

    Pagano, Michael P

    2016-08-01

    The purpose of this article is to expand on prior research in end-of-life communication and death and dying communication apprehension, by developing a unique course that utilizes a hospice setting and an applied, service-learning approach. Therefore, this essay describes and discusses both students' and my experiences over a 7-year period from 2008 through 2014. The courses taught during this time frame provided an opportunity to analyze students' responses, experiences, and discoveries across semesters/years and cocultures. This unique, 3-credit, 14-week, service-learning, end-of-life communication course was developed to provide an opportunity for students to learn the theories related to this field of study and to apply that knowledge through volunteer experiences via interactions with dying patients and their families. The 7 years of author's notes, plus the 91 students' electronically submitted three reflection essays each (273 total documents) across four courses/years, served as the data for this study. According to the students, verbally in class discussions and in numerous writing assignments, this course helped lower their death and dying communication apprehension and increased their willingness to interact with hospice patients and their families. Furthermore, the students' final research papers clearly demonstrated how utilizing a service-learning approach allowed them to apply classroom learnings and interactions with dying patients and their families at the hospice, to their analyses of end-of-life communication theories and behaviors. The results of these classes suggest that other, difficult topic courses (e.g., domestic violence, addiction, etc.) might benefit from a similar pedagogical approach.

  20. Hypoxia treatment reverses neurodegenerative disease in a mouse model of Leigh syndrome.

    PubMed

    Ferrari, Michele; Jain, Isha H; Goldberger, Olga; Rezoagli, Emanuele; Thoonen, Robrecht; Cheng, Kai-Hung; Sosnovik, David E; Scherrer-Crosbie, Marielle; Mootha, Vamsi K; Zapol, Warren M

    2017-05-23

    The most common pediatric mitochondrial disease is Leigh syndrome, an episodic, subacute neurodegeneration that can lead to death within the first few years of life, for which there are no proven general therapies. Mice lacking the complex I subunit, Ndufs4, develop a fatal progressive encephalopathy resembling Leigh syndrome and die at ≈60 d of age. We previously reported that continuously breathing normobaric 11% O 2 from an early age prevents neurological disease and dramatically improves survival in these mice. Here, we report three advances. First, we report updated survival curves and organ pathology in Ndufs4 KO mice exposed to hypoxia or hyperoxia. Whereas normoxia-treated KO mice die from neurodegeneration at about 60 d, hypoxia-treated mice eventually die at about 270 d, likely from cardiac disease, and hyperoxia-treated mice die within days from acute pulmonary edema. Second, we report that more conservative hypoxia regimens, such as continuous normobaric 17% O 2 or intermittent hypoxia, are ineffective in preventing neuropathology. Finally, we show that breathing normobaric 11% O 2 in mice with late-stage encephalopathy reverses their established neurological disease, evidenced by improved behavior, circulating disease biomarkers, and survival rates. Importantly, the pathognomonic MRI brain lesions and neurohistopathologic findings are reversed after 4 wk of hypoxia. Upon return to normoxia, Ndufs4 KO mice die within days. Future work is required to determine if hypoxia can be used to prevent and reverse neurodegeneration in other animal models, and to determine if it can be provided in a safe and practical manner to allow in-hospital human therapeutic trials.

  1. 15 CFR 2301.24 - Final Federal payment.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... reasonable costs incurred in completing the planning or construction project are less than the total project..., however, the actual costs incurred in completing the project are more than the estimated total project costs, in no case will the final Federal funds paid exceed the grant award. ...

  2. Project LIFE, 1963-1975. Final Report.

    ERIC Educational Resources Information Center

    Pfau, Glenn S.

    Presented is the final report on Project Life (Language Improvement to Facilitate Education), a 12-year (1963-75) project which developed filmstrips and supplementary materials for teaching language to deaf children. General overview and historical review sections include information on project goals and objectives, administration agencies and…

  3. Development of a simulation tool to analyze the orientation of LCPs during extrusion process

    NASA Astrophysics Data System (ADS)

    Ahmadzadegan, Arash

    In this thesis, different aspects of the rheology and directionality of the liquid crystalline polymers (LCPs) are investigated. The rheology of LCPs are modeled with different rheological models in different die geometries. The final goal in modeling the rheology and directionality of LCPs is to have a better understanding of their rheology during extrusion processing methods inside extrusion dies and eventually produce more isotropic films of LCPs. An attempt to design a die geometry that produces more isotropic films was made and it was shown that it is possible to use the inertia of the polymer to generate a more isotropic velocity profile at the lip of the die. This isotropic velocity profile can lead to alignment of directors along the streamlines and produce an isotropic film of LCP. It is shown that the rheological properties of the LCP should be altered to have a very low viscosity for this type of die to work. To be able to investigate the effect of processing on directionality of LCPs, it is essential to develop a method to simulate the directionality based on processing conditions. As a result, a user defined function (UDF) code was added to ANSYSRTM ~FLUENTRTM~ to simulate the directionality of LCPs. The rheology of the LCP is modeled using power-law fluid model and the consistency index (K) and power-law index (n) were estimated based on the experimental measurements done with capillary rheometry. Three main phenomena that affect the directionality namely effects of Franks elastic energy, the effect of shear and the effect of movement of crystals with the bulk of polymer are investigated. The results of this simulation are close to physical phenomena seen in real LCPs. To quantify the directionality of the LCPs, the order parameter of the domain were calculated and compared for different flow and fluid conditions. All polymers including LCPs are viscoelastic fluids in molten state. To understand the rheology of LCPs, a die-swell experiment was carried out using LCP material and Polypropylene (PP). For this experiment a capillary die with two different land-lengths was designed and built. The die-swell of the materials were measured optically according to ISO standards and the dependence of the die swell for materials on rheological properties is investigated. To simulate the viscoelasticity of LCPs numerically, ANSYSRTM ~POLYFLOWRTM~ was used. ANSYSRTM ~POLYFLOWRTM~ has several viscoelastic models and is designed to simulate extrusion processes. The geometry of the capillary die designed for the experiments was modeled in ANSYSRTM ~POLYFLOWRTM~ and the results were compared with the experimental results obtained for LCP and PP. It is shown that the morphology of the polymer should be considered into account to have a correct simulation of die swell.

  4. Yakima Fisheries Project : Final Environmental Impact Statement.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    United States. Bonneville Power Administration; Washington; Confederated Tribes and Bands of the Yakama Nation, Washington.

    1996-01-01

    BPA proposes to fund several fishery-related activities in the Yakima River Basin. These activities, known as the Yakima Fisheries Project (YFP), would be jointly managed by the State of Washington and the Yakima Indian Nation. The YFP is included in the Northwest Power Planning Council`s (Council`s) fish and wildlife program. The Council selected the Yakima River system for attention because fisheries resources are severely reduced from historical levels and because there is a significant potential for enhancement of these resources. BPA`s proposed action is to fund (1) information gathering on the implementation of supplementation techniques and on feasibility of reintroducingmore » coho salmon in an environment where native populations have become extinct; (2) research activities based on continuous assessment, feedback and improvement of research design and activities ({open_quotes}adaptive management{close_quotes}); and (3) die construction, operation, and maintenance of facilities for supplementing populations of upper Yakima spring chinook salmon. Examined in addition to No Action are two alternatives for action: (1) supplementation of depressed natural populations of upper Yakima spring chinook and (2) that same supplementation plus a study to determine the feasibility of reestablishing naturally spawning population and a significant fall fishery for coho in the Yakima Basin. Alternative 2 is the preferred action. A central hatchery would be built for either alternative, as well as three sites with six raceways each for acclimation and release of spring chinook smolts. Major issues examined in the Revised Draft EIS include potential impacts of the project on genetic and ecological resources of existing fish populations, on water quality and quantity, on threatened and endangered species listed under the Endangered Species Act, and on the recreational fishery.« less

  5. The dying child and surviving family members.

    PubMed

    Shrier, D K

    1980-12-01

    This overview of death and dying focuses on the dying child and surviving family members. Children's concepts of death at different developmental stages are reviewed. These range from an inability to distinguish death from other forms of separation prior to age 3, through partial concepts of death until, by age 10 to 15 years, children are able to conceptualize death as universal, inevitable and final. The importance of adults assisting in the child's growing comprehension of death is stressed. The stages of grief and mourning, as outlined by Kubler-Ross, are reviewed from the perspective of the child and family: denial, anger, bargaining, depression and acceptance. Recognition is given to the variations in coping styles among different family members. The special circumstances related to the death of an infant and the impact of the death of a child on the surviving siblings are discussed. Specific helpful interventions to assist families in coping with mourning are described. The death of a child remains one of the most painful and difficult events for a family and its physician to accept.

  6. Georgia Deaf-Blind Project. Final Report, 1992-1995. State and Multi-State Projects for Children with Deaf-Blindness.

    ERIC Educational Resources Information Center

    Georgia State Dept. of Education, Atlanta.

    This final report describes activities and accomplishments of the Georgia Deaf-Blind Project, a 3-year federally supported project encompassing 159 counties and providing technical assistance to 237 infants, children, and youth with deaf-blindness along with their families and their service providers. Project accomplishments included: (1) more…

  7. 76 FR 10938 - Notice of Final Federal Agency Actions on Sunrise Project, I-205 to Rock Creek Junction...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-28

    ... on Sunrise Project, I-205 to Rock Creek Junction: Clackamas County, OR AGENCY: Federal Highway.... 139(l)(1). The actions relate to a proposed highway project, Sunrise Project, I-205 to Rock Creek... Project, I-205 to Rock Creek Junction Final Environmental Impact Statement, Record of Decision and other...

  8. Increased levels of dioxin-like substances in adipose tissue in patients with deep infiltrating endometriosis.

    PubMed

    Martínez-Zamora, M A; Mattioli, L; Parera, J; Abad, E; Coloma, J L; van Babel, B; Galceran, M T; Balasch, J; Carmona, F

    2015-05-01

    Are the levels of biologically active and the most toxic dioxin-like substances in adipose tissue of patients with deep infiltrating endometriosis (DIE) higher than in a control group without endometriosis? DIE patients have higher levels of dioxins and polychlorinated biphenyls (PCBs) in adipose tissue compared with controls without endometriosis. Some studies have investigated the levels of dioxin-like substances, in serum samples, in patients with endometriosis, with inconsistent results. Case-control study including two groups of patients. The study group (DIE group) consisted of 30 patients undergoing laparoscopic surgery because of DIE. In all patients, an extensive preoperative work-up was performed including clinical exploration, magnetic resonance imaging (MRI) and transvaginal sonography. All patients with DIE underwent a confirmatory histological study for DIE after surgery. The non-endometriosis control group (control group), included the next consecutive patient undergoing laparoscopic surgery in our center due to adnexal benign gynecological disease (ovarian or tubal procedures other than endometriosis) after each DIE patient, and who did not present any type of endometriosis. During the surgical procedure 1-2 g of adipose tissue from the omentum were obtained. Dioxin-like substances were analyzed in adipose tissue in DIE patients and controls without endometriosis. The total toxic equivalence and concentrations of both dioxins and PCBs were significantly higher in patients with DIE in comparison with the control group (P < 0.05), mainly due to the significantly higher values of the two most toxic dioxins (2,3,7,8-tetrachlorodibenzo-p-dioxin [2,3,7,8-TCDD] and 1,2,3,7,8-pentachlorodibenzo-p-dioxin [1,2,3,7,8-PeCDD]) (P < 0.01 for each compound). The levels of furan 2,3,4,7,8-PeCDF were statistically higher in the DIE group compared with controls. Only four congeners of PCBs had toxic equivalence values and concentrations that were statistically higher in patients with DIE, but these included the most toxic and carcinogenic PCB-126 (PCB-114 P < 0.05; PCB-156 P < 0.05; PCB-189 P = 0.04; PCB-126 P < 0.01). Since few patients were recruited, the study is only exploratory. Our results need to be confirmed in larger and more heterogeneous population studies since environmental and even genetic factors involved in determining dioxins and PCBs widely vary in different countries. Furthermore, the strict eligibility criteria used may preclude generalization of the results to other populations and the surgery-based sampling frame may induce a selection bias. Finally, adipose tissue was obtained only from the omentum, and not from other adipose tissue of the body. Our results suggest a potential role of dioxin-like substances in the pathogenesis of DIE. Further studies are warranted to confirm our findings. None. Not applicable. © The Author 2015. Published by Oxford University Press on behalf of the European Society of Human Reproduction and Embryology. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  9. 76 FR 19744 - Final Tropic to Hatch 138 kV Transmission Line Project Environmental Impact Statement and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-08

    ... DEPARTMENT OF AGRICULTURE Forest Service Final Tropic to Hatch 138 kV Transmission Line Project..., has prepared a Final Environmental Impact Statement (FEIS) for the Tropic to Hatch 138 kV Transmission.... ADDRESSES: Copies of the Tropic to Hatch 138 kV Transmission Line Project FEIS/PMPA for the Grand Staircase...

  10. Almost certain escape from black holes in final state projection models.

    PubMed

    Lloyd, Seth

    2006-02-17

    Recent models of the black-hole final state suggest that quantum information can escape from a black hole by a process akin to teleportation. These models rely on a controversial process called final-state projection. This Letter discusses the self-consistency of the final-state projection hypothesis and investigates escape from black holes for arbitrary final states and for generic interactions between matter and Hawking radiation. Quantum information escapes with fidelity approximately = (8/3pi)2: only half a bit of quantum information is lost on average, independent of the number of bits that escape from the hole.

  11. 76 FR 67178 - Wells Hydroelectric Project; Notice of Availability of the Final Environmental Impact Statement...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-31

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Project No. 2149-152] Wells Hydroelectric Project; Notice of Availability of the Final Environmental Impact Statement for the Wells... application for license for the Wells Hydroelectric Project (FERC No. 2149), located on the Columbia River in...

  12. 75 FR 7029 - Notice of Availability of the Final Environmental Assessment for Solar Roof Project

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-16

    ... Assessment for Solar Roof Project AGENCY: United States Geological Survey. ACTION: Notice of availability... Final Environmental Assessment for the Solar Roof Project and by this notice is announcing its... Individuals wishing to receive copies of the Environmental Assessment for the Solar Roof Project should...

  13. Special Education Evaluation Project for University Affiliated Facilities. Final Report.

    ERIC Educational Resources Information Center

    Burrello, Leonard C.; And Others

    The final report of the Special Education Evaluation Project for 16 University Affiliated Facilities (UAF) centers provides a chronological review of the project which focused on the training of persons to work with mentally retarded or other handicapped individuals. Outlined are project objectives including the development of descriptors useful…

  14. Space Shuttle Projects

    NASA Image and Video Library

    1988-06-21

    The predominant themes are: a new beginning (sunrise), a safe mission (stylized launch and plume), the building upon the traditional strengths of NASA (the red vector which symbolizes aeronautics on the original NASA insignia), and a remembrance of their seven colleagues who died aboard Challenger (the seven-starred Big Dipper). The patch was designed by artist Stephen R. Hustvedt of Annapolis, MD.

  15. Contributing factors for drought in United States forest ecosystems under projected future climates and their uncertainty

    Treesearch

    Charlie Luce; James M. Vose; Neil Pederson; John Campbell; Connie Millar; Patrick Kormos; Ross Woods

    2016-01-01

    Observations of increasing global forest die-off related to drought are leading to more questions about potential increases in drought occurrence, severity, and ecological consequence in the future. Dry soils and warm temperatures interact to affect trees during drought; so understanding shifting risks requires some understanding of changes in both temperature...

  16. Monitoring the Health of Sugar Maple, "Acer Saccharum"

    ERIC Educational Resources Information Center

    Carlson, Martha

    2013-01-01

    The sugar maple, "Acer saccharum," is projected to decline and die in 88 to 100 percent of its current range in the United States. An iconic symbol of the northeastern temperate forest and a dominant species in this forest, the sugar maple is identified as the most sensitive tree in its ecosystem to rising temperatures and a warming…

  17. Research Update: Outdoor Education Fatalities in Australia

    ERIC Educational Resources Information Center

    Brookes, Andrew

    2007-01-01

    This paper is part of an on-going project to examine outdoor education related deaths in Australia since 1960. It records eleven incidents not included in previous papers in this series. A total of 14 students or staff died in the incidents. The paper reviews the incidents and identifies what further lessons can be learned about fatality…

  18. Mortality from Sudden Unexpected Death in Epilepsy (SUDEP) in a Cohort of Adults with Intellectual Disability

    ERIC Educational Resources Information Center

    Kiani, R.; Tyrer, F.; Jesu, A.; Bhaumik, S.; Gangavati, S.; Walker, G.; Kazmi, S.; Barrett, M.

    2014-01-01

    Background: People with intellectual disability (ID) and epilepsy are more likely to die prematurely than the general population. A significant number of deaths in people with epilepsy may be potentially preventable through better seizure control, regular monitoring and raising awareness among patients and carers. The aim of this project was to…

  19. In Memoriam

    NASA Astrophysics Data System (ADS)

    Howard Myers died in September 2000, at age 72. He had been a member (Planetology) since 1971.Richard E. Ewing has been elected to the Board of Directors for the National Space Biomedical Research Institute, a consortium of research institutions that focuses on research for human exploration of space. Projects concentrate on space health issues such as bone loss, sleep disturbances, nutrition, and radiation exposure.

  20. Tree Owner's Manual for the Northeastern Midwestern United States

    Treesearch

    Jill Johnson; Gary Johnson; Maureen McDonough; Lisa Burban; Janette Monear

    2008-01-01

    One common issue facing our urban forests is the fact that trees are dying prematurely. Many are planted improperly, setting them up for failure. Many do not receive regular maintenance. And few are adequately protected during construction projects. To help remedy this issue, the Forest Service has created this Tree Owner's Manual. Just like the owner...

  1. Exploring the Experiences of People with Intellectual Disabilities when Service Users Die

    ERIC Educational Resources Information Center

    Ryan, Karen; Guerin, Suzanne; Dodd, Philip; McEvoy, John

    2011-01-01

    Research is lacking on the effect of the deaths of fellow service users on people with intellectual disabilities. This qualitative study formed part of a project which aimed to describe the provision of palliative care to people with intellectual disabilities in Ireland and to assess the population's palliative care needs. We report on findings…

  2. Xylobios: patterns, roles and determinants of saproxylic diversity in Belgian deciduous forests

    Treesearch

    Philippe Fayt; Etienne Branquart; Marc Dufrene; Jean-Marc Henin; Christophe Pontegnie; Veerle Versteirt

    2003-01-01

    The XYLOBIOS project aims to study patterns, roles and determinants of saproxylic diversity (i.e., species richness and abundance of organisms which are dependent upon the dead or dying wood of moribund or dead trees, or upon the presence of other saproxylics) found in Belgian beech Fagus sylvatica and oak Quercus spp. forests. The...

  3. The strokes that killed Churchill, Roosevelt, and Stalin.

    PubMed

    Ali, Rohaid; Connolly, Ian D; Li, Amy; Choudhri, Omar A; Pendharkar, Arjun V; Steinberg, Gary K

    2016-07-01

    From February 4 to 11, 1945, President Franklin D. Roosevelt of the United States, Soviet Union Premier Joseph Stalin, and British Prime Minister Winston Churchill met near Yalta in Crimea to discuss how post-World War II (WWII) Europe should be organized. Within 2 decades of this conference, all 3 men had died. President Roosevelt died 2 months after the Yalta Conference due to a hemorrhagic stroke. Premier Stalin died 8 years later, also due to a hemorrhagic stroke. Finally, Prime Minister Churchill died 20 years after the conference because of complications due to stroke. At the time of Yalta, these 3 men were the leaders of the most powerful countries in the world. The subsequent deterioration of their health and eventual death had varying degrees of historical significance. Churchill's illness forced him to resign as British prime minister, and the events that unfolded immediately after his resignation included Britain's mismanagement of the Egyptian Suez Crisis and also a period of mistrust with the United States. Furthermore, Roosevelt was still president and Stalin was still premier at their times of passing, so their deaths carried huge political ramifications not only for their respective countries but also for international relations. The early death of Roosevelt, in particular, may have exacerbated post-WWII miscommunication between America and the Soviet Union-miscommunication that may have helped precipitate the Cold War.

  4. Providing high-quality care at the end of life: the role of education and guidance.

    PubMed

    Dobson, Jill

    2017-11-09

    Palliative care in the UK has been ranked as the best in the world. So where did palliative care go so wrong that a 168-page document is required to inform staff how to care for dying patients if it has been going so well for so long? Those nearing the end of their life deserve to be given optimum care, attention, compassion and consideration, but this is not always the case. The Liverpool Care Pathway was a tool originally devised to help health professionals provide high-quality end-of-life care to people in the final phase of life. This tool, when used in the correct way, could provide the 'gold standard' of end-of-life care for patients. However, a national review found that rather than a tick-box exercise, care of the dying should be centred around individualised care planning for the dying patient, as highlighted in the publication of the guidance: One Chance to Get It Right. Care of the dying is a complex skill that requires nurses to provide some of the most challenging care, and for which many nurses have received little or no training. The implementation of this guidance into practice will require thoughtful change management, abandoning an old way of working in order to ensure excellence and high-quality care for patients nearing the end of life.

  5. Robust optimization of the billet for isothermal local loading transitional region of a Ti-alloy rib-web component based on dual-response surface method

    NASA Astrophysics Data System (ADS)

    Wei, Ke; Fan, Xiaoguang; Zhan, Mei; Meng, Miao

    2018-03-01

    Billet optimization can greatly improve the forming quality of the transitional region in the isothermal local loading forming (ILLF) of large-scale Ti-alloy ribweb components. However, the final quality of the transitional region may be deteriorated by uncontrollable factors, such as the manufacturing tolerance of the preforming billet, fluctuation of the stroke length, and friction factor. Thus, a dual-response surface method (RSM)-based robust optimization of the billet was proposed to address the uncontrollable factors in transitional region of the ILLF. Given that the die underfilling and folding defect are two key factors that influence the forming quality of the transitional region, minimizing the mean and standard deviation of the die underfilling rate and avoiding folding defect were defined as the objective function and constraint condition in robust optimization. Then, the cross array design was constructed, a dual-RSM model was established for the mean and standard deviation of the die underfilling rate by considering the size parameters of the billet and uncontrollable factors. Subsequently, an optimum solution was derived to achieve the robust optimization of the billet. A case study on robust optimization was conducted. Good results were attained for improving the die filling and avoiding folding defect, suggesting that the robust optimization of the billet in the transitional region of the ILLF was efficient and reliable.

  6. The ethics of hastening death during terminal weaning.

    PubMed

    Walton, Laura; Bell, Dominic

    2013-12-01

    Withdrawal of life-sustaining medical treatment (LSMT) is under scrutiny as next-of-kin challenge medical decision-making in the courts and established end-of-life pathways are withdrawn in the face of public criticism. With persistent lobbying for medically assisted dying as the other side of the coin, and professional advice that doctors distance themselves from this activity, the fine line between defensible palliative care and hastening a death needs to be unambiguously defined, particularly with additional confounders such as transplantation initiatives. The medical literature in this domain is dominated by ethical debate on euthanasia and medically assisted dying rather than defensibility within intensive care at the point of withdrawal of LSMT. The process and, therefore, the timing of dying is open to manipulation by intensivists, families, other hospital physicians, courts of law and extraneous influences such as organ donation. Intensivists faced with these challenging processes need to consider some key principles to help them navigate the management of dying. They need to demonstrate transparency in order to engender trust, be responsive to the dynamically evolving needs of patient and family, avoid ambiguity, show consistency and predictability and, finally, they need to conform with society's expectations and professional standards to achieve defensibility for their actions. Adherence to these principles is likely to minimize conflict, maximize patient benefit, maintain public confidence and avoid professional jeopardy.

  7. Project to Incorporate Anthropological Concepts of Human Diversity in Secondary School Social Studies Curricula (Project Anthropology). Final Report, 2/1/80 to 1/31/82.

    ERIC Educational Resources Information Center

    Giannangelo, Duane M.; And Others

    Learning modules emphasizing the anthropological aspects of human and race relations to supplement social studies textbooks used in grades 7-12 were developed. The final report describes pre-project activities, module development, and project evaluation and accomplishments. Pre-project activities included media publicity, reviewing social studies…

  8. KSC-2014-3638

    NASA Image and Video Library

    2014-08-29

    CAPE CANAVERAL, Fla. -- A wreath honoring former NASA astronaut Steven R. Nagel is displayed beside his photo at the Space Shuttle Atlantis exhibit at the Kennedy Space Center Visitor Complex in Florida. Nagel died Aug. 21 after a long illness. He was 67 years old. Nagel served as a mission specialist on his first space shuttle flight, STS-51G, in 1985. He was pilot on his second shuttle flight, STS-61A, also in 1985. He commanded his final two flights, STS-37 and STS-55, in 1991 and 1993, respectively. He logged a total of 723 hours in space. To learn more about Nagel's career, visit http://www.nasa.gov/press/2014/august/former-nasa-astronaut-steven-nagel-veteran-of-four-shuttle-flights-dies-at-67/. Photo credit: NASA/Dimitri Gerondidakis

  9. KSC-2014-3643

    NASA Image and Video Library

    2014-08-29

    CAPE CANAVERAL, Fla. – Former NASA astronaut Jon McBride speaks at a wreath-laying ceremony honoring former NASA astronaut Steven R. Nagel at the Space Shuttle Atlantis exhibit at the Kennedy Space Center Visitor Complex in Florida. Nagel died Aug. 21 after a long illness. He was 67 years old. Nagel served as a mission specialist on his first space shuttle flight, STS-51G, in 1985. He was pilot on his second shuttle flight, STS-61A, also in 1985. He commanded his final two flights, STS-37 and STS-55, in 1991 and 1993, respectively. He logged a total of 723 hours in space. To learn more about Nagel's career, visit http://www.nasa.gov/press/2014/august/former-nasa-astronaut-steven-nagel-veteran-of-four-shuttle-flights-dies-at-67/. Photo credit: NASA/Dimitri Gerondidakis

  10. KSC-2014-3639

    NASA Image and Video Library

    2014-08-29

    CAPE CANAVERAL, Fla. -- A wreath honoring former NASA astronaut Steven R. Nagel is displayed beside his photo at the Space Shuttle Atlantis exhibit at the Kennedy Space Center Visitor Complex in Florida. Nagel died Aug. 21 after a long illness. He was 67 years old. Nagel served as a mission specialist on his first space shuttle flight, STS-51G, in 1985. He was pilot on his second shuttle flight, STS-61A, also in 1985. He commanded his final two flights, STS-37 and STS-55, in 1991 and 1993, respectively. He logged a total of 723 hours in space. To learn more about Nagel's career, visit http://www.nasa.gov/press/2014/august/former-nasa-astronaut-steven-nagel-veteran-of-four-shuttle-flights-dies-at-67/. Photo credit: NASA/Dimitri Gerondidakis

  11. 77 FR 5566 - Notice of Availability of the Final EIS for the HB In-Situ Solution Mine Project, Eddy County...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-03

    ...] Notice of Availability of the Final EIS for the HB In-Situ Solution Mine Project, Eddy County, New Mexico... Statement (Final EIS) for the HB In-Situ Solution Mine Project, and by this notice is announcing its... the Federal Register. ADDRESSES: Copies of the HB In-Situ Solution Mining EIS are available for public...

  12. Vocational Evaluation and Work Adjustment Bulletin; Vol. 8, Special Edition: Vocational Evaluation Project Final Report Part 1.

    ERIC Educational Resources Information Center

    Vocational Evaluation and Work Adjustment Association, Washington, DC.

    The first of three parts of the Vocational Evaluation Project final report contains an editorial, two task force reports, and brief summaries of the seven task force reports which comprise the final report. The editorial summarizes the project's purpose, its activities for the three years of its existence, and its results, and describes the task…

  13. 38 CFR 3.1605 - Death while traveling under prior authorization or while hospitalized by the Department of...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... War I, World War II, or Korean service, but who when medically examined were not finally accepted for... 38 Pensions, Bonuses, and Veterans' Relief 1 2012-07-01 2012-07-01 false Death while traveling... purpose of: (1) Examination; or (2) Treatment; or (3) Care dies enroute, burial, funeral, plot, interment...

  14. 38 CFR 3.1605 - Death while traveling under prior authorization or while hospitalized by the Department of...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... War I, World War II, or Korean service, but who when medically examined were not finally accepted for... 38 Pensions, Bonuses, and Veterans' Relief 1 2010-07-01 2010-07-01 false Death while traveling... purpose of: (1) Examination; or (2) Treatment; or (3) Care dies enroute, burial, funeral, plot, interment...

  15. 38 CFR 3.1605 - Death while traveling under prior authorization or while hospitalized by the Department of...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... War I, World War II, or Korean service, but who when medically examined were not finally accepted for... 38 Pensions, Bonuses, and Veterans' Relief 1 2013-07-01 2013-07-01 false Death while traveling... purpose of: (1) Examination; or (2) Treatment; or (3) Care dies enroute, burial, funeral, plot, interment...

  16. 38 CFR 3.1605 - Death while traveling under prior authorization or while hospitalized by the Department of...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... War I, World War II, or Korean service, but who when medically examined were not finally accepted for... 38 Pensions, Bonuses, and Veterans' Relief 1 2011-07-01 2011-07-01 false Death while traveling... purpose of: (1) Examination; or (2) Treatment; or (3) Care dies enroute, burial, funeral, plot, interment...

  17. 38 CFR 3.1605 - Death while traveling under prior authorization or while hospitalized by the Department of...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... War I, World War II, or Korean service, but who when medically examined were not finally accepted for... 38 Pensions, Bonuses, and Veterans' Relief 1 2014-07-01 2014-07-01 false Death while traveling... purpose of: (1) Examination; or (2) Treatment; or (3) Care dies enroute, burial, funeral, plot, interment...

  18. The Gonzo Scientist. Slaying monsters for science.

    PubMed

    Bohannon, John

    2008-06-20

    Slaying Monsters for Science John Bohannon The first scientific conference held in Azeroth, the online universe of the role-playing game World of Warcraft, went off virtually without a hitch. Although the participants all died during the final day's social event - a massive raid on an enemy fort - they agree that this event is a glimpse at the future of scientific exchange.

  19. New focus on forests

    Treesearch

    Katherine Unger; Divya Abhat.; Constance Millar; Greg [featured scientists] McPherson

    2010-01-01

    It would appear that forests are finally having their day—and not a moment too soon. Around the world, trees are dying at an alarming rate, besieged by illegal logging, agricultural conversion, wildfire, and drought. According to the United Nations Food and Agriculture Organization, 13 million  hectares of the world’s forests are now lost to deforestation every year....

  20. 78 FR 76280 - Polyethylene Retail Carrier Bags From the People's Republic of China: Affirmative Preliminary...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-17

    ... length, and which appears ready to undergo the final step in the production process, i.e., to use a die... March 3, 2014. Notification of the International Trade Commission Pursuant to section 781(e) of the Act... Components Produced in the Foreign Country Is a Significant Portion of the Total Value of the Merchandise E...

  1. A Celebration of Life: Memories of an Arab-American in Cleveland. ADC Issues, Issue #7.

    ERIC Educational Resources Information Center

    Macron, Mary

    This document discusses the life celebrations of Arab American immigrants to Cleveland from the late 1870s. Assembled from what is largely an oral tradition of family history, the booklet describes the home life, weddings, and final partings when elderly relatives returned to the homeland or died in the United States. The economic situation and…

  2. Recently published papers: dying Swans and other stories.

    PubMed

    Rose, Hannah; Venn, Richard

    2006-01-01

    The use of pulmonary artery catheters is under debate yet again. We look at two recent trials evaluating their impact on mortality. Our suspicions regarding obesity are proven and we also look at a simple, cost effective method of reducing ventilator-associated pneumonia. Finally, an intervention to improve the poor outcome associated with out-of hospital cardiac arrests is evaluated.

  3. Optimum Design of Forging Process Parameters and Preform Shape under Uncertainties

    NASA Astrophysics Data System (ADS)

    Repalle, Jalaja; Grandhi, Ramana V.

    2004-06-01

    Forging is a highly complex non-linear process that is vulnerable to various uncertainties, such as variations in billet geometry, die temperature, material properties, workpiece and forging equipment positional errors and process parameters. A combination of these uncertainties could induce heavy manufacturing losses through premature die failure, final part geometric distortion and production risk. Identifying the sources of uncertainties, quantifying and controlling them will reduce risk in the manufacturing environment, which will minimize the overall cost of production. In this paper, various uncertainties that affect forging tool life and preform design are identified, and their cumulative effect on the forging process is evaluated. Since the forging process simulation is computationally intensive, the response surface approach is used to reduce time by establishing a relationship between the system performance and the critical process design parameters. Variability in system performance due to randomness in the parameters is computed by applying Monte Carlo Simulations (MCS) on generated Response Surface Models (RSM). Finally, a Robust Methodology is developed to optimize forging process parameters and preform shape. The developed method is demonstrated by applying it to an axisymmetric H-cross section disk forging to improve the product quality and robustness.

  4. Modelling the Cast Component Weight in Hot Chamber Die Casting using Combined Taguchi and Buckingham's π Approach

    NASA Astrophysics Data System (ADS)

    Singh, Rupinder

    2018-02-01

    Hot chamber (HC) die casting process is one of the most widely used commercial processes for the casting of low temperature metals and alloys. This process gives near-net shape product with high dimensional accuracy. However in actual field environment the best settings of input parameters is often conflicting as the shape and size of the casting changes and one have to trade off among various output parameters like hardness, dimensional accuracy, casting defects, microstructure etc. So for online inspection of the cast components properties (without affecting the production line) the weight measurement has been established as one of the cost effective method (as the difference in weight of sound and unsound casting reflects the possible casting defects) in field environment. In the present work at first stage the effect of three input process parameters (namely: pressure at 2nd phase in HC die casting; metal pouring temperature and die opening time) has been studied for optimizing the cast component weight `W' as output parameter in form of macro model based upon Taguchi L9 OA. After this Buckingham's π approach has been applied on Taguchi based macro model for the development of micro model. This study highlights the Taguchi-Buckingham based combined approach as a case study (for conversion of macro model into micro model) by identification of optimum levels of input parameters (based on Taguchi approach) and development of mathematical model (based on Buckingham's π approach). Finally developed mathematical model can be used for predicting W in HC die casting process with more flexibility. The results of study highlights second degree polynomial equation for predicting cast component weight in HC die casting and suggest that pressure at 2nd stage is one of the most contributing factors for controlling the casting defect/weight of casting.

  5. Perinatal suicide in Ontario, Canada: a 15-year population-based study.

    PubMed

    Grigoriadis, Sophie; Wilton, Andrew S; Kurdyak, Paul A; Rhodes, Anne E; VonderPorten, Emily H; Levitt, Anthony; Cheung, Amy; Vigod, Simone N

    2017-08-28

    Death by suicide during the perinatal period has been understudied in Canada. We examined the epidemiology of and health service use related to suicides during pregnancy and the first postpartum year. In this retrospective, population-based cohort study, we linked health administrative databases with coroner death records (1994-2008) for Ontario, Canada. We compared sociodemographic characteristics, clinical features and health service use in the 30 days and 1 year before death between women who died by suicide perinatally, women who died by suicide outside of the perinatal period and living perinatal women. The perinatal suicide rate was 2.58 per 100 000 live births, with suicide accounting for 51 (5.3%) of 966 perinatal deaths. Most suicides occurred during the final quarter of the first postpartum year, with highest rates in rural and remote regions. Perinatal women were more likely to die from hanging (33.3% [17/51]) or jumping or falling (19.6% [10/51]) than women who died by suicide non-perinatally ( p = 0.04). Only 39.2% (20/51) had mental health contact within the 30 days before death, similar to the rate among those who died by suicide non-perinatally (47.7% [762/1597]; odds ratio [OR] 0.71, 95% confidence interval [CI] 0.40-1.25). Compared with living perinatal women matched by pregnancy or postpartum status at date of suicide, perinatal women who died by suicide had similar likelihood of non-mental health primary care and obstetric care before the index date but had a lower likelihood of pediatric contact (64.5% [20/31] v. 88.4% [137/155] at 30 days; OR 0.24, 95% CI 0.10-0.58). The perinatal suicide rate for Ontario during the period 1994-2008 was comparable to international estimates and represents a substantial component of Canadian perinatal mortality. Given that deaths by suicide occur throughout the perinatal period, all health care providers must be collectively vigilant in assessing risk. © 2017 Canadian Medical Association or its licensors.

  6. Looking for the Self: Phenomenology, Neurophysiology and Philosophical Significance of Drug-induced Ego Dissolution.

    PubMed

    Millière, Raphaël

    2017-01-01

    There is converging evidence that high doses of hallucinogenic drugs can produce significant alterations of self-experience, described as the dissolution of the sense of self and the loss of boundaries between self and world. This article discusses the relevance of this phenomenon, known as "drug-induced ego dissolution (DIED)", for cognitive neuroscience, psychology and philosophy of mind. Data from self-report questionnaires suggest that three neuropharmacological classes of drugs can induce ego dissolution: classical psychedelics, dissociative anesthetics and agonists of the kappa opioid receptor (KOR). While these substances act on different neurotransmitter receptors, they all produce strong subjective effects that can be compared to the symptoms of acute psychosis, including ego dissolution. It has been suggested that neuroimaging of DIED can indirectly shed light on the neural correlates of the self. While this line of inquiry is promising, its results must be interpreted with caution. First, neural correlates of ego dissolution might reveal the necessary neurophysiological conditions for the maintenance of the sense of self, but it is more doubtful that this method can reveal its minimally sufficient conditions. Second, it is necessary to define the relevant notion of self at play in the phenomenon of DIED. This article suggests that DIED consists in the disruption of subpersonal processes underlying the "minimal" or "embodied" self, i.e., the basic experience of being a self rooted in multimodal integration of self-related stimuli. This hypothesis is consistent with Bayesian models of phenomenal selfhood, according to which the subjective structure of conscious experience ultimately results from the optimization of predictions in perception and action. Finally, it is argued that DIED is also of particular interest for philosophy of mind. On the one hand, it challenges theories according to which consciousness always involves self-awareness. On the other hand, it suggests that ordinary conscious experience might involve a minimal kind of self-awareness rooted in multisensory processing, which is what appears to fade away during DIED.

  7. 2+2+2 Dissemination Project Final Report.

    ERIC Educational Resources Information Center

    Sloane, Diana; And Others

    An overview is provided in this three-part final report of a project designed to disseminate information to assist California high schools, Regional Occupation Programs, and colleges in developing and strengthening 2+2+2 programs. Part I reviews the following project objectives: (1) hire a project coordinator and technical assistant; (2) develop a…

  8. 78 FR 45268 - Notice of Availability of the San Diego Gas & Electric Ocotillo Sol Solar Project Final...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-26

    ... decommission the Ocotillo Sol Solar Project, a solar photovoltaic (PV) power plant facility, on approximately... Applicant's Proposed Project to construct, operate, maintain, and decommission a 100-acre solar PV facility...] Notice of Availability of the San Diego Gas & Electric Ocotillo Sol Solar Project Final Environmental...

  9. SELF (Supports for Early Learning Foundations): A Non-Directed Model Demonstration Project. Final Report.

    ERIC Educational Resources Information Center

    Harrison, Holly

    This final report describes achievements and activities of Project SELF (Supports for Early Learning Foundations), a federally funded project in New Mexico which developed, evaluated, and replicated an innovative model that provides strategies for early interventionists and families to support early learning foundations. The project identified…

  10. Pacific Basin Deaf-Blind Project. State & Multi State Projects for Children with Deaf-Blindness. Final Report, 1992-1995.

    ERIC Educational Resources Information Center

    Kelly, Dotty; Guerrero, Vincent Leon

    This final report describes activities and accomplishments of the Pacific Basin Deaf-Blind Project, a 3-year federally funded project to provide technical assistance to public and private agencies, institutions, and organizations providing early intervention, educational, transitional, vocational, early identification, and related services to…

  11. THe Case Method of Instruction (CMI) Project. Final Report.

    ERIC Educational Resources Information Center

    McWilliam, P. J.; And Others

    This final report describes the Case Method of Instruction (CMI) Project, a project to develop, field test, and disseminate training materials to facilitate the use of the Case Method of Instruction by inservice and preservice instructors in developmental disabilities. CMI project activities focused on developing a collection of case stories and…

  12. Evaluation of the Rural Math Excel Partnership Project Final Report

    ERIC Educational Resources Information Center

    Nagle, Katherine; Pratt-Williams, Jaunelle; Schmidt, Rebecca; Swantek, Cara; Lyulchenko, Marianna; McGhee, Raymond

    2016-01-01

    This is the final external evaluation report prepared by SRI International for the Rural Math Excel Partnership (RMEP) project, an investing in innovation (i3) development project funded by the U.S. Department of Education. Operated by Virginia Advanced Study Strategies, Inc. (VASS), the RMEP project included six rural school districts (LEAs) in…

  13. The Amherst Project. Final Report.

    ERIC Educational Resources Information Center

    Hampshire Coll., Amherst, MA.

    This final report submitted by the Committee on the Study of History at Hampshire College describes the Amherst Project, a research and development project devoted to fostering the newer inquiry approaches in the study of United States history. The project's main focus has been on secondary schools, but has also encompassed junior high and adult…

  14. 75 FR 36151 - Notice of Final Federal Agency Actions on Proposed Highway in California; Notice of Statute of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-24

    ... were taken, are described in the Final Environmental Assessment (FEA) for the project, approved via... FHWA project records. The FEA, FONSI, and other project records are available by contacting Caltrans at...

  15. LYNX community advocacy & service engagement (CASE) project final report.

    DOT National Transportation Integrated Search

    2009-05-14

    This report is a final assessment of the Community Advocacy & Service Engagement (CASE) project, a LYNX-FTA research project designed : to study transit education and public engagement methods in Central Florida. In the Orlando area, as in other part...

  16. Illinois Clean Coal Institute 2005 annual report. Final technical report for the period September 1st, 2004, through August 31, 2005 on projects funded by the Illinois Department of Commerce and Economic Opportunity

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    NONE

    2005-11-08

    This final technical report contains the abstracts and executive summaries of projects funded through the Illinois Clean Coal Institute solicitation entitled 'Request for proposals No. 04-1(ICCI/RFP04-1)'. Support of these projects is by the Office of Coal Development and Department of Commerce and Economic Opportunity. The projects fall into the following categories: advanced coal mining technologies; coal preparation and coal production business practice; management of coal combustion byproducts; commercialization and technology transfer. Final project extensions are also recorded.

  17. Case study of lean manufacturing application in a die casting manufacturing company

    NASA Astrophysics Data System (ADS)

    Ching, Ng Tan; Hoe, Clarence Chan Kok; Hong, Tang Sai; Ghobakhloo, Morteza; Pin, Chen Kah

    2015-05-01

    The case study of lean manufacturing aims to study the application of lean manufacturing in a die casting manufacturing company located in Pulau Penang, Malaysia. This case study describes mainly about the important concepts and applications of lean manufacturing which could gradually help the company in increasing the profit by studying and analyzing their current manufacturing process and company culture. Many approaches of lean manufacturing are studied in this project which includes: 5S housekeeping, Kaizen, and Takt Time. Besides, the lean tools mentioned, quality tool such as the House of Quality is being used as an analysis tool to continuously improve the product quality. In short, the existing lean culture in the company is studied and analyzed, with recommendations written at the end of this paper.

  18. Language used by health care professionals to describe dying at an acute care hospital.

    PubMed

    Wentlandt, Kirsten; Toupin, Philippe; Novosedlik, Natalia; Le, Lisa W; Zimmermann, Camilla; Kaya, Ebru

    2018-05-21

    To understand the language used to describe the deterioration and death of patients in an acute academic tertiary care centre, and to identify whether patient diagnoses or palliative care(PC) involvement was associated with clearer descriptions of this process. We conducted a retrospective chart review of the final admission of 150 patients who died on an inpatient internal medicine unit. Conventional and summative content analysis was performed of the language used to describe, either directly or indirectly, that the patient's death was imminent. Of the 150 deaths, the median age was 79.5(range22-101), 58% were male, and 69% spoke English. A total of 45% of deaths were from cancer, and 66% occurred with prior PC team involvement. There was no documentation of the dying process in 18(12%) of charts. In the remainder, clinicians' documentation of imminent death fell into three categories: 1 identification of the current state using specific labels, e.g. 'dying'(24.7%), or 'end of life'(15.3%), or less specific language, 'unwell' or 'doing poorly'(6.0%); 2 predicting the future state using specific or more vague predictions: e.g.'hours to days'(7.3%) or 'poor or guarded prognosis'(26.0%); 3 using care provided to the patient to imply patient status: e.g. palliative care(49.3%) or comfort care(28.7%). PC involvement, but not a malignant diagnosis, was associated with more frequent use of specific language to describe the current(p=0.004) or future state(p=0.02). Death and dying in hospital is inadequately documented and is often described using unclear and vague language. PC involvement is associated with clearer language to describe this process. Copyright © 2018. Published by Elsevier Inc.

  19. Premortem interventions in dying children to optimise organ donation: an ethical analysis.

    PubMed

    Brierley, Joe; Shaw, David

    2016-07-01

    A range of interventions in dying patients can improve both the possibility of successful organ donation and the likely long-term success of transplantation. The ethical and legal issues surrounding such interventions, which most frequently occur in the context of donation after circulatory determination of death, are complex, controversial and many remain unresolved. This is true with adults, but even more so with children, where the issue of organ donation and premortem interventions to facilitate it, are highly sensitive. Essentially, such interventions are being undertaken in dying children who cannot medically benefit from them, though arguments have been advanced that becoming a donor might be in a child's extended best interest. However, certain interventions carry a potential risk, although small, of direct harm and of course overall objections to child donation after circulatory determination of death per se are still expressed in the literature. But, unlike the case in critically ill adults, those giving permission for such interventions are normally able to fully participate in decision-making, and indeed to consent, to both donation and premortem interventions. We review the issue of the use of premortem interventions in dying children to facilitate organ donation, including decision-making and ethical justification. Individual interventions are then considered, including an ethical analyse of their use. Finally, we recommend an approach using a combination of welfare checklist strategy, coupled with the establishment of an agreed zone of parental discretion about individual interventions which might be used in dying children to increase the possibility of successful organ donation. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

  20. Hypoxia treatment reverses neurodegenerative disease in a mouse model of Leigh syndrome

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ferrari, Michele; Jain, Isha H.; Goldberger, Olga

    The most common pediatric mitochondrial disease is Leigh syn-drome, an episodic, subacute neurodegeneration that can lead to death within the first few years of life, for which there are no proven general therapies. Mice lacking the complex I subunit, Ndufs4, develop a fatal progressive encephalopathy resembling Leigh syndrome and die at ≈60 d of age. We previously reported that contin-uously breathing normobaric 11% O 2 from an early age prevents neurological disease and dramatically improves survival in these mice. Here, we report three advances. First, we report updated sur-vival curves and organ pathology in Ndufs4 KO mice exposed to hypoxiamore » or hyperoxia. Whereas normoxia-treated KO mice die from neurodegeneration at about 60 d, hypoxia-treated mice eventually die at about 270 d, likely from cardiac disease, and hyperoxia-treated mice die within days from acute pulmonary edema. Second, we report that more conservative hypoxia regimens, such as contin-uous normobaric 17% O 2 or intermittent hypoxia, are ineffective in preventing neuropathology. Finally, we show that breathing normobaric 11% O 2 in mice with late-stage encephalopathy re-verses their established neurological disease, evidenced by im-proved behavior, circulating disease biomarkers, and survival rates. Importantly, the pathognomonic MRI brain lesions and neurohistopathologic findings are reversed after 4 wk of hyp-oxia. Upon return to normoxia, Ndufs4 KO mice die within days. Future work is required to determine if hypoxia can be used to prevent and reverse neurodegeneration in other animal models, and to determine if it can be provided in a safe and practical manner to allow in-hospital human therapeutic trials.« less

  1. Hypoxia treatment reverses neurodegenerative disease in a mouse model of Leigh syndrome

    DOE PAGES

    Ferrari, Michele; Jain, Isha H.; Goldberger, Olga; ...

    2017-05-08

    The most common pediatric mitochondrial disease is Leigh syn-drome, an episodic, subacute neurodegeneration that can lead to death within the first few years of life, for which there are no proven general therapies. Mice lacking the complex I subunit, Ndufs4, develop a fatal progressive encephalopathy resembling Leigh syndrome and die at ≈60 d of age. We previously reported that contin-uously breathing normobaric 11% O 2 from an early age prevents neurological disease and dramatically improves survival in these mice. Here, we report three advances. First, we report updated sur-vival curves and organ pathology in Ndufs4 KO mice exposed to hypoxiamore » or hyperoxia. Whereas normoxia-treated KO mice die from neurodegeneration at about 60 d, hypoxia-treated mice eventually die at about 270 d, likely from cardiac disease, and hyperoxia-treated mice die within days from acute pulmonary edema. Second, we report that more conservative hypoxia regimens, such as contin-uous normobaric 17% O 2 or intermittent hypoxia, are ineffective in preventing neuropathology. Finally, we show that breathing normobaric 11% O 2 in mice with late-stage encephalopathy re-verses their established neurological disease, evidenced by im-proved behavior, circulating disease biomarkers, and survival rates. Importantly, the pathognomonic MRI brain lesions and neurohistopathologic findings are reversed after 4 wk of hyp-oxia. Upon return to normoxia, Ndufs4 KO mice die within days. Future work is required to determine if hypoxia can be used to prevent and reverse neurodegeneration in other animal models, and to determine if it can be provided in a safe and practical manner to allow in-hospital human therapeutic trials.« less

  2. 76 FR 65746 - Notice of Availability of Joint Final Environmental Impact Statement/Final Environmental Impact...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-24

    ... Boulevard. The project will consist of up to 128 wind turbines (1.5 to 3.0 MW each) with a generating... Statement/Final Environmental Impact Report for the Tule Wind Project, California, and Notice of Intent To... Final Environmental Impact Report (EIR) as a joint environmental analysis document for Tule Wind, LLC's...

  3. A Model System for the Design and Maintenance of Related Instruction Curriculum for Approved U.S. Department of Labor Apprenticeship Programs; Phase III. Final Report and Final Evaluation Report.

    ERIC Educational Resources Information Center

    Lane Community Coll., Eugene, OR.

    A final report and final evaluation report of Phase III are provided for a project to establish a national clearinghouse for apprenticeship-related instructional materials. The final report provides a summary and a narrative account of these project activities: identification of materials; identification of apprenticeship curriculum needs;…

  4. Experimental projects in graduate theoretical physics courses

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Rosner, J.L.

    1996-10-01

    Some beginning graduate courses in physics at the University of Chicago have been taught with final projects in addition to or in place of written final examinations. Although these courses and many of the projects are theoretical, experimental projects have been encouraged, with some success. A few examples are discussed. {copyright} {ital 1996 American Association of Physics Teachers.}

  5. The Indiana Deafblind Services Project: Services for Children with Deafblindness Program. Final Performance Report.

    ERIC Educational Resources Information Center

    Indiana State Univ., Terre Haute. Blumberg Center for Interdisciplinary Studies in Special Education.

    This final report describes activities and accomplishments of the Indiana Deaf-Blind Services Project, a 4-year federally funded project to enhance and further develop coordinated direct services to children and youth, birth through 2 and ages 18 through 21. The project also was designed to provide technical assistance to public and private…

  6. Illinois State Project: Services for Children with Deaf-Blindness Program. Final Performance Report.

    ERIC Educational Resources Information Center

    Dorsey, Christine

    This final report describes activities and accomplishments of the Illinois state project on services for children with deaf-blindness, a 3-year federally supported project to address the needs of children (ages birth to 21) who are deaf-blind. Project activities included inservice training and technical assistance, development of a comprehensive…

  7. Color management of porcelain veneers: influence of dentin and resin cement colors.

    PubMed

    Dozic, Alma; Tsagkari, Maria; Khashayar, Ghazal; Aboushelib, Moustafa

    2010-01-01

    Porcelain veneers have become an interesting treatment option to correct the shape and color of anterior teeth. Because of their limited thickness and high translucency, achieving a good color match is influenced by several variables. The aim of this work was to investigate the influence of natural dentin and resin cement colors on final color match of porcelain veneers. A preselected shade tab (A1) was chosen as the target color for a maxillary central incisor, and its color parameters (L*a*b*) were measured using a digital spectrophotometer (SpectroShade, MHT). Nine natural dentin colors (Natural Die Material, Ivoclar Vivadent) representing a wide range of tooth colors were used to prepare resin replicas of the maxillary central incisor with a standard preparation for porcelain veneers. The prepared porcelain veneers (IPS Empress Esthetic, A1, 0.6 mm thick, Ivoclar Vivadent) were cemented on the resin dies (nine groups of natural dentin colors) using seven shades of resin cement (Variolink Veneers, Ivoclar Vivadent). The L*a*b* values of the cemented veneers were measured, and DE values were calculated against the preselected target color (A1). DE greater than 3.3 was considered as a significant color mismatch detectable by the human eye. The seven shades of resin cement had no significant influence on the final color of the veneers, as the measured DE values were almost identical for every test group. On the other hand, the color of natural dentin was a significant factor that influenced final color match. None of the 63 tested combinations (nine natural dentin colors and seven resin cement colors) produced an acceptable color match. Thin porcelain veneers cannot mask underlying tooth color even when different shades of resin cement are used. Incorporation of opaque porcelain (high chroma) may improve final color match.

  8. In Living Memory: The Dying Art of Learning Poetry and a Case for Revival

    ERIC Educational Resources Information Center

    Pullinger, Debbie

    2012-01-01

    This article considers the practice of learning poems and the value of poetry in the memory, and emerges from the Cambridge Poetry Teaching Project, a small-scale research study co-ordinated through the Faculty of Education at the University of Cambridge. Drawing on the subset of findings in relation to learning and memory, the essay locates the…

  9. Predictors of CVD among breast cancer survivors in an integrated health system | Division of Cancer Prevention

    Cancer.gov

    PROJECT SUMMARY / ABSTRACT Breast cancer survivors are at high risk of developing and dying from cardiovascular disease (CVD) following breast cancer diagnosis, but subpopulations at increased risk and targets for intervention have not been well- characterized. A growing body of literature links CVD with specific cardiotoxic cancer treatments. CVD risk among breast cancer

  10. The role of ungulate herbivory and management on ecosystem patterns and processes: future direction of the Starkey project.

    Treesearch

    Martin Vavra; Michael J. Wisdom; John G. Kie; John G. Cook; Robert A. Riggs

    2004-01-01

    In the national forests of the Blue Mountains, a high percentage of commercial tree species, such as Douglas fir (Pseudotsuga menziessi) and true firs (Abies spp.), have died as a result of overcrowding on drier sites, drought and insects (Johnson et al. 1995, Quigley and Arbelbide 1997). These conditions are typical of...

  11. The European mesothelioma epidemic

    PubMed Central

    Peto, J; Decarli, A; Vecchia, C La; Levi, F; Negri, E

    1999-01-01

    Projections for the period 1995–2029 suggest that the number of men dying from mesothelioma in Western Europe each year will almost double over the next 20 years, from 5000 in 1998 to about 9000 around 2018, and then decline, with a total of about a quarter of a million deaths over the next 35 years. The highest risk will be suffered by men born around 1945–50, of whom about 1 in 150 will die of mesothelioma. Asbestos use in Western Europe remained high until 1980, and substantial quantities are still used in several European countries. These projections are based on the fit of a simple age and birth cohort model to male pleural cancer mortality from 1970 to 1989 for six countries (Britain, France, Germany, Italy, The Netherlands and Switzerland) which together account for three-quarters of the population of Western Europe. The model was tested by comparing observed and predicted numbers of deaths for the period 1990–94. The ratio of mesothelioma to recorded pleural cancer mortality has been 1.6:1 in Britain but was assumed to be 1:1 in other countries. © 1999 Cancer Research Campaign PMID:10027347

  12. Energy Saving Melting and Revert Reduction Technology (E-SMARRT): Mechanical Performance of Dies

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    R. Allen Miller, Principal Investigator; Kabiri-Bamoradian, Contributors: Khalil; Delgado-Garza, Abelardo

    2011-09-13

    As a net shape process, die casting is intrinsically efficient and improvements in energy efficiency are strongly dependent on design and process improvements that reduce scrap rates so that more of the total consumed energy goes into acceptable, usable castings. A casting that is distorted and fails to meet specified dimensional requirements is typically remelted but this still results in a decrease in process yield, lost productivity, and increased energy consumption. This work focuses on developing, and expanding the use of, computer modeling methods that can be used to improve the dimensional accuracy of die castings and produce die designsmore » and machine/die setups that reduce rejection rates due to dimensional issues. A major factor contributing to the dimensional inaccuracy of the casting is the elastic deformations of the die cavity caused by the thermo mechanical loads the dies are subjected to during normal operation. Although thermal and die cavity filling simulation are widely used in the industry, structural modeling of the die, particularly for managing part distortion, is not yet widely practiced. This may be due in part to the need to have a thorough understanding of the physical phenomenon involved in die distortion and the mathematical theory employed in the numerical models to efficiently model the die distortion phenomenon. Therefore, two of the goals of this work are to assist in efforts to expand the use of structural modeling and related technologies in the die casting industry by 1) providing a detailed modeling guideline and tutorial for those interested in developing the necessary skills and capability and 2) by developing simple meta-models that capture the results and experience gained from several years of die distortion research and can be used to predict key distortion phenomena of relevance to a die caster with a minimum of background and without the need for simulations. These objectives were met. A detailed modeling tutorial was provided to NADCA for distribution to the industry. Power law based meta-models for predicting machine tie bar loading and for predicting maximum parting surface separation were successfully developed and tested against simulation results for a wide range of machines and experimental data. The models proved to be remarkably accurate, certainly well within the requirements for practical application. In addition to making die structural modeling more accessible, the work advanced the state-of-the-art by developing improved modeling of cavity pressure effects, which is typically modeled as a hydrostatic boundary condition, and performing a systematic analysis of the influence of ejector die design variables on die deflection and parting plane separation. This cavity pressure modeling objective met with less than complete success due to the limits of current finite element based fluid structure interaction analysis methods, but an improved representation of the casting/die interface was accomplished using a combination of solid and shell elements in the finite element model. This approximation enabled good prediction of final part distortion verified with a comprehensive evaluation of the dimensions of test castings produced with a design experiment. An extra deliverable of the experimental work was development of high temperature mechanical properties for the A380 die casting alloy. The ejector side design objective was met and the results were incorporated into the metamodels described above. This new technology was predicted to result in an average energy savings of 2.03 trillion BTU's/year over a 10 year period. Current (2011) annual energy saving estimates over a ten year period, based on commercial introduction in 2009, a market penetration of 70% by 2014 is 4.26 trillion BTU's/year by 2019. Along with these energy savings, reduction of scrap and improvement in casting yield will result in a reduction of the environmental emissions associated with the melting and pouring of the metal which will be saved as a result of this technology. The average annual estimate of CO2 reduction per year through 2020 is 0.085 Million Metric Tons of Carbon Equivalent (MM TCE).« less

  13. The Polish Genetic Database of Victims of Totalitarianisms.

    PubMed

    Ossowski, A; Kuś, M; Kupiec, T; Bykowska, M; Zielińska, G; Jasiński, M E; March, A L

    2016-01-01

    This paper describes the creation of the Polish Genetic Database of Victims of Totalitarianism and the first research conducted under this project. On September 28th 2012, the Pomeranian Medical University in Szczecin and the Institute of National Remembrance-Commission for Prosecution of Crimes against the Polish Nation agreed to support the creation of the Polish Genetic Database of Victims of Totalitarianism (PBGOT, www.pbgot.pl). The purpose was to employ state-of-the-art methods of forensic genetics to identify the remains of unidentified victims of Communist and Nazi totalitarian regimes. The database was designed to serve as a central repository of genetic information of the victim's DNA and that of the victim's nearest living relatives, with the goal of making a positive identification of the victim. Along the way, PGBOT encountered several challenges. First, extracting useable DNA samples from the remains of individuals who had been buried for over half a century required forensic geneticists to create special procedures and protocols. Second, obtaining genetic reference material and historical information from the victim's closest relatives was both problematic and urgent. The victim's nearest living relatives were part of a dying generation, and the opportunity to obtain the best genetic and historical information about the victims would soon die with them. For this undertaking, PGBOT assembled a team of historians, archaeologists, forensic anthropologists, and forensic geneticists from several European research institutions. The field work was divided into five broad categories: (1) exhumation of victim remains and storing their biological material for later genetic testing; (2) researching archives and historical data for a more complete profile of those killed or missing and the families that lost them; (3) locating the victim's nearest relatives to obtain genetic reference samples (swabs), (4) entering the genetic data from both victims and family members into a common database; (5) making a conclusive, final identification of the victim. PGBOT's first project was to identify victims of the Communist regime buried in hidden mass graves in the Powązki Military Cemetery in Warsaw. Throughout 2012 and 2013, PGBOT carried out archaeological exhumations in the Powązki Military Cemetery that resulted in the recovery of the skeletal remains of 194 victims in several mass graves. Of the 194 sets of remains, more than 50 victims have been successfully matched and identified through genetic evidence. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

  14. Minnesota Deaf-Blind Technical Assistance Project. Final Report.

    ERIC Educational Resources Information Center

    Kloos, Eric

    This final report describes activities and accomplishments of the 3-year federally supported Minnesota Deaf-Blind Technical Assistance Project. The project provided training and technical assistance, information sharing, and support services to families of children with deaf-blindness. Activities and accomplishments included: collaboration with…

  15. 78 FR 60021 - Proposed Collection: Comment Request for Regulation Project

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-30

    ... DEPARTMENT OF THE TREASURY Internal Revenue Service [REG-120616-03(TD 9346 Final Regulations and Removal of Temporary Regulations)] Proposed Collection: Comment Request for Regulation Project AGENCY.... Regulation Project Number: REG-120616-03 (T.D. 9346 Final Regulations and Removal of Temporary Regulations...

  16. 49 CFR 256.7 - Financial assistance.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... passenger terminal, under subsection 4(i)(2) of the Act, may be expended for the following project costs incurred after the date of final project approval: (1) Acquisition or long-term lease of real property or... project implementation; (2) Final architectural and engineering construction documentation, including all...

  17. X-43A Final Flight Observations

    NASA Technical Reports Server (NTRS)

    Grindle, Laurie

    2011-01-01

    The presentation will provide an overview of the final flight of the NASA X-43A project. The project consisted of three flights, two planned for Mach 7 and one for Mach 10. The first flight, conducted on June 2, 2001, was unsuccessful and resulted in a nine-month mishap investigation. A two-year return to flight effort ensued and concluded when the second Mach 7 flight was successfully conducted on March 27, 2004. The third and final flight, which occurred on November 16, 2004, was the first Mach 10 flight demonstration of an airframe-integrated, scramjet-powered, hypersonic vehicle. As such, the final flight presented first time technical challenges in addition to final flight project closeout concerns. The goals and objectives for the third flight as well as those for the project will be presented. The configuration of the Hyper-X stack including the X-43A, Hyper-X launch vehicle, and Hyper-X research vehicle adapter wil also be presented. Mission differences, vehicle modifications and lessons learned from the first and second flights as they applied to the third flight will also be discussed. Although X-43A flight 3 was always planned to be the final flight of the X-43A project, the X-43 program had two other vehicles and corresponding flight phases in X-43C and X-43B. Those other projects never manifested under the X-43 banner and X-43A flight 3 also became the final flight of X-43 program.

  18. The second Tuesday. We talk about feeling sorry for yourself.

    PubMed

    Albom, M

    1999-01-01

    The following is an excerpt from Tuesdays with Morrie, a best-selling book by Mitch Albom about his relationship with a former professor and mentor. Albom rediscovered Morrie Schwartz in the last months of the older man's life. Knowing he was dying, Morrie visited with Mitch in his study every Tuesday. Their rekindled relationship turned into one final class: lessons in how to live.

  19. Mark XIV Torpedo Case Study

    DTIC Science & Technology

    2011-02-26

    Bureau of Ordnance in the meantime had corresponded with Albert Einstein at Princeton University on a variety of issues including torpedo detonation... Einstein was paid $25/day as a consultant and quickly understood the problem. The contact exploder’s firing pin located in the very front warhead...were finally identified and corrected. In all seriousness, God only knows how many submariners died as a result of those defective torpedoes, which

  20. A Dying Child in the Family: The Child's and Sibling's Perspective. Selected Papers, Number 60.

    ERIC Educational Resources Information Center

    Said, John

    Children and adolescents have different understandings of death. For the baby, death is equated with separation. For toddlers, grief occurs when they realize the person is not returning. The preschool child who tends to live in the present with no clear concept of past or future will not understand the finality. Around ages 4 and 5, death is often…

  1. ROHHAD Syndrome: The Girl who Forgets to Breathe.

    PubMed

    Sanklecha, Mukesh; Sundaresan, Suba; Udani, Vrajesh

    2016-04-01

    ROHHAD syndrome is an exceedingly rare cause of central hypoventilation. A 7-year-old girl with ROHHAD syndrome who had central hypoventilation, rapid weight gain, multiple cardiac arrests and hyperprolactinemia. She required prolonged and repeated ventilation, and finally died due to complications of ventilation. ROHHAD Syndrome should be suspected in any child who presents with obesity, behavioral changes or autonomic instability following a neural crest tumor.

  2. A view of death and dying among the Chinese and Japanese.

    PubMed

    Char, D F; Tom, K S; Young, G C; Murakami, T; Ames, R

    1996-12-01

    The practices of medicine around the world have been fused into that of faith and religion. In serving our patients' need to accept death, physicians must also be sensitive to this underlying basic human concern as they prepare for this final journey. The Chinese and Japanese, reflecting their belief in Buddhism, perceive death as a natural part and an extension of life itself.

  3. 76 FR 52274 - Expansion of State Home Care for Parents of a Child Who Died While Serving in the Armed Forces

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-22

    ... programs or the rights and obligations of recipients thereof; or (4) raise novel legal or policy issues... impact on a substantial number of small entities as they are defined in the Regulatory Flexibility Act. The State homes referenced in this final rule are State government entities under the control of State...

  4. Staff Helping Attain Relevant Education (Project SHARE): Final Evaluation Report, 1992-93. OREA Report.

    ERIC Educational Resources Information Center

    Ranadive, Jyoti

    Project SHARE (Staff Helping Attain Relevant Education), a project funded by Title VII of the Elementary and Secondary Education Act, was in its third and final year of operation in 1992-93, in eight primary schools in the Bronx, Brooklyn, and Manhattan (New York). The project served 141 limited English proficient students from low-income families…

  5. New Jersey Technical Assistance Project (N.J. TAP): "Educational Resources and Support Services on Behalf of Children with Multiple Sensory Impairment." Final Report.

    ERIC Educational Resources Information Center

    New Jersey State Dept. of Education, Trenton.

    This final report describes activities and accomplishments of the New Jersey Technical Assistance Project, a project to improve educational resources and support services for students with multiple sensory impairment (deaf-blindness). Activities and accomplishments are presented in a tabular format for each project goal and objective. The project…

  6. [Organization of palliative medicine in the clinic and ambulatory care].

    PubMed

    Jonen-Thielemann, I

    1998-01-01

    To describe the idea of palliative medicine and its forms of organization in the inpatient and outpatient sectors, and in particular to describe the projects for palliative medicine at the University of Cologne, specifying costs and the 1996 statistics of the palliative care unit. Palliative medicine comprises the alleviative treatment, nursing and accompaniment of the incurably ill in the far advanced stage of disease, including the physical, mental, psychic, spiritual and social domains. The underlying concept is "to live until you die" and dying in dignity at the natural end of life. Facilities for palliative medicine in the hospital: palliative care unit, palliative care sector, palliative care consultation service; forms of organization in the outpatient sector: home care service, domiciliary palliative care service and outpatient hospice; independent facilities: hospices-inpatient and part-inpatient. Costs of palliative treatment in the projects of the University of Cologne: palliative care unit: 457.33 DM for one patient per day, 12,092.20 DM average costs per patient admission in 1996 (n = 186); home care service: 200.00 DM flat rate per patient per day; inpatient hospice in Cologne-Heimersdorf: 300.00 DM for one patient per day (home care service and hospice entail additional costs for medical treatment, medication and nursing accessories). Palliative medicine is expensive; only a few patients have the benefit of this; relatives may suppose to be relieved of the burden of their responsibilities; however: the severely ill and dying patients of the hospital experience the best possible care at home or in a "family atmosphere"; gain in experience of palliative medicine and multiplier function, research; awaking our society to thoughts of their own hour of death and what comes after it.

  7. WA4 Volunteering in partnership: a public health approach to delivering compassionate care to those at end of life and the frail elderly.

    PubMed

    Wilson, Gail

    2015-04-01

    Young people are often denied volunteering experiences with vulnerable dying people as this is considered to be 'too distressing'. This project challenged this paternalistic attitude and trained young people to volunteer in the hospice, and other organisations to enhance the delivery of compassionate care. To promote dignity in care, for older people, people with dementia, those at end of life and those with learning disabilities. To reduce social isolation and the stigma associated with dying and being old. To create new volunteering opportunities for young people to raise their awareness of the needs of the dying and the frail elderly. Develop a model of best practice - that could be replicated in other parts of the country. A health promotion approach was used combining education and a community development, partnership approach. Results 120 Volunteers delivered over 3,650 hrs of volunteering activities, supporting individuals to engage in social activities. The project broke myths about having 16-18 year olds volunteering. The relationship between the hospice and the local community has strengthened and the employability skills for the young people taking part have increased. 16% of those who responded to an exit survey had gained full time employment, 9% had gained university places. The personalisation of care for the frail elderly and those at end of life has increased by the use of volunteers. Young volunteers need mentoring. Staff needs support to feel confident to utilise the volunteers and let go of myths about risks. © 2015, Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

  8. Recurrent Die-Offs of Adult Coho Salmon Returning to Spawn in Puget Sound Lowland Urban Streams

    PubMed Central

    Scholz, Nathaniel L.; Myers, Mark S.; McCarthy, Sarah G.; Labenia, Jana S.; McIntyre, Jenifer K.; Ylitalo, Gina M.; Rhodes, Linda D.; Laetz, Cathy A.; Stehr, Carla M.; French, Barbara L.; McMillan, Bill; Wilson, Dean; Reed, Laura; Lynch, Katherine D.; Damm, Steve; Davis, Jay W.; Collier, Tracy K.

    2011-01-01

    Several Seattle-area streams in Puget Sound were the focus of habitat restoration projects in the 1990s. Post-project effectiveness monitoring surveys revealed anomalous behaviors among adult coho salmon returning to spawn in restored reaches. These included erratic surface swimming, gaping, fin splaying, and loss of orientation and equilibrium. Affected fish died within hours, and female carcasses generally showed high rates (>90%) of egg retention. Beginning in the fall of 2002, systematic spawner surveys were conducted to 1) assess the severity of the adult die-offs, 2) compare spawner mortality in urban vs. non-urban streams, and 3) identify water quality and spawner condition factors that might be associated with the recurrent fish kills. The forensic investigation focused on conventional water quality parameters (e.g., dissolved oxygen, temperature, ammonia), fish condition, pathogen exposure and disease status, and exposures to metals, polycyclic aromatic hydrocarbons, and current use pesticides. Daily surveys of a representative urban stream (Longfellow Creek) from 2002–2009 revealed premature spawner mortality rates that ranged from 60–100% of each fall run. The comparable rate in a non-urban stream was <1% (Fortson Creek, surveyed in 2002). Conventional water quality, pesticide exposure, disease, and spawner condition showed no relationship to the syndrome. Coho salmon did show evidence of exposure to metals and petroleum hydrocarbons, both of which commonly originate from motor vehicles in urban landscapes. The weight of evidence suggests that freshwater-transitional coho are particularly vulnerable to an as-yet unidentified toxic contaminant (or contaminant mixture) in urban runoff. Stormwater may therefore place important constraints on efforts to conserve and recover coho populations in urban and urbanizing watersheds throughout the western United States. PMID:22194802

  9. Narrative medicine and death in the ICU: word clouds as a visual legacy.

    PubMed

    Vanstone, Meredith; Toledo, Feli; Clarke, France; Boyle, Anne; Giacomini, Mita; Swinton, Marilyn; Saunders, Lois; Shears, Melissa; Zytaruk, Nicole; Woods, Anne; Rose, Trudy; Hand-Breckenridge, Tracey; Heels-Ansdell, Diane; Anderson-White, Shelley; Sheppard, Robert; Cook, Deborah

    2016-11-24

    The Word Cloud is a frequent wish in the 3 Wishes Project developed to nurture peace and ease the grieving process for dying critically ill patients. The objective was to examine whether Word Clouds can act as a heuristic approach to encourage a narrative orientation to medicine. Narrative medicine is an approach which can strengthen relationships, compassion and resilience. Word Clouds were created for 42 dying patients, and we interviewed 37 family members and 73 clinicians about their impact. We conducted a directed qualitative content analysis, using the 3 stages of narrative medicine (attention, representation, affiliation) to examine the narrative medicine potential of Word Clouds. The elicitation of stories for the Word Cloud promotes narrative attention to the patient as a whole person. The distillation of these stories into a list of words and the prioritisation of those words for arrangement in the collage encourages a representation that did not enforce a beginning, middle or end to the story of the patient's life. Strong affiliative connections were achieved through the honouring of patients, caring for families and sharing of memories encouraged through the creation, sharing and discussion of Word Clouds. In the 3 Wishes Project, Word Clouds are 1 way that families and clinicians honour a dying patient. Engaging in the process of making a Word Cloud can promote a narrative orientation to medicine, forging connections, making meaning through reminiscence and leaving a legacy of a loved one. Documenting and displaying words to remember someone in death reaffirms their life. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

  10. 76 FR 19772 - Environmental Impacts Statements; Notice of Availability

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-08

    ... Barker 208-735-2072. EIS No. 20110101, Final EIS, USFS, CO, Big Moose Vegetation Management Project... Salvage Project, Proposal to Treat Timer Harvest, Prescribe Fire, and Mechanical Thinning, Uinta-Wasatch... No. 20110107, Final EIS, FHWA, IL, Illinois 336 Corridor Project, (Federal Aid Primary Route 315...

  11. 77 FR 14416 - Notice of Availability of a Final Environmental Impact Statement and Final Environmental Impact...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-09

    ... wind turbine generators; a substation; administration, operations and maintenance facilities... Action (the ``Refined Project''). Under the Refined Project configuration, only 112 wind turbines... Report for the Pattern Energy Group's Ocotillo Express Wind Energy Project and Proposed California Desert...

  12. 78 FR 35886 - Applications for New Awards; National Institute on Disability and Rehabilitation Research...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-14

    ... Disability and Rehabilitation Research (NIDRR)--Disability and Rehabilitation Research Projects and Centers... notice of final priorities for the Disability and Rehabilitation Research Projects and Centers Program... included in the notice of final priorities for the Disability and Rehabilitation Research Projects and...

  13. 77 FR 76067 - Notice of Availability of a Proposed Land Use Plan Amendment and Final Environmental Impact...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-26

    ... Statement for the Proposed McCoy Solar Energy Project, CA AGENCY: Bureau of Land Management, Interior... amendment and final environmental impact statement (EIS) for the McCoy Solar Energy Project (project)--a photovoltaic solar electricity generation [[Page 76068

  14. KSC-2014-3642

    NASA Image and Video Library

    2014-08-29

    CAPE CANAVERAL, Fla. – Former NASA astronaut Kenneth Cameron speaks at a wreath-laying ceremony honoring former NASA astronaut Steven R. Nagel at the Space Shuttle Atlantis exhibit at the Kennedy Space Center Visitor Complex in Florida. Former NASA astronaut Jon McBride looks on, at right. Nagel died Aug. 21 after a long illness. He was 67 years old. Nagel served as a mission specialist on his first space shuttle flight, STS-51G, in 1985. He was pilot on his second shuttle flight, STS-61A, also in 1985. He commanded his final two flights, STS-37 and STS-55, in 1991 and 1993, respectively. He logged a total of 723 hours in space. To learn more about Nagel's career, visit http://www.nasa.gov/press/2014/august/former-nasa-astronaut-steven-nagel-veteran-of-four-shuttle-flights-dies-at-67/. Photo credit: NASA/Dimitri Gerondidakis

  15. KSC-2014-3641

    NASA Image and Video Library

    2014-08-29

    CAPE CANAVERAL, Fla. -- Kennedy Space Center Director Bob Cabana speaks at a wreath-laying ceremony honoring former NASA astronaut Steven R. Nagel at the Space Shuttle Atlantis exhibit at the Kennedy Space Center Visitor Complex in Florida. Former NASA astronaut Jon McBride looks on, at right. Nagel died Aug. 21 after a long illness. He was 67 years old. Nagel served as a mission specialist on his first space shuttle flight, STS-51G, in 1985. He was pilot on his second shuttle flight, STS-61A, also in 1985. He commanded his final two flights, STS-37 and STS-55, in 1991 and 1993, respectively. He logged a total of 723 hours in space. To learn more about Nagel's career, visit http://www.nasa.gov/press/2014/august/former-nasa-astronaut-steven-nagel-veteran-of-four-shuttle-flights-dies-at-67/. Photo credit: NASA/Dimitri Gerondidakis

  16. End-of-Life Medical Costs of Medicaid Cancer Patients.

    PubMed

    Tangka, Florence K L; Subramanian, Sujha; Sabatino, Susan A; Howard, David H; Haber, Susan; Hoover, Sonja; Richardson, Lisa C

    2015-06-01

    To quantify end-of-life (EOL) medical costs for adult Medicaid beneficiaries diagnosed with cancer. We linked Medicaid administrative data with 2000-2003 cancer registry data to identify 3,512 adult Medicaid beneficiaries who died after a cancer diagnosis and matched them to a cohort of beneficiaries without cancer who died during the same period. We used multivariable regression analysis to estimate incremental per-person EOL cost after controlling for beneficiaries' age, race/ethnicity, sex, cancer site, and state of residence. End-of-life costs during the final 4 months of life were about $10,000 higher for Medicaid cancer patients than for those without cancer. Medicaid cancer patients are more intensive users of inpatient and ambulatory services than are Medicaid patients without cancer. Medicaid cancer patients who die soon after diagnosis have higher costs of care and use inpatient services more intensely than do Medicaid patients without cancer. Medicaid cancer patients incur substantially higher EOL costs than noncancer patients. This increased cost may reflect the cost of palliative care. Future studies should assess the types and timing of services provided to Medicaid cancer patients at the EOL. © Health Research and Educational Trust.

  17. End-of-Life Medical Costs of Medicaid Cancer Patients

    PubMed Central

    Tangka, Florence KL; Subramanian, Sujha; Sabatino, Susan A; Howard, David H; Haber, Susan; Hoover, Sonja; Richardson, Lisa C

    2015-01-01

    Objectives To quantify end-of-life (EOL) medical costs for adult Medicaid beneficiaries diagnosed with cancer. Data Sources We linked Medicaid administrative data with 2000–2003 cancer registry data to identify 3,512 adult Medicaid beneficiaries who died after a cancer diagnosis and matched them to a cohort of beneficiaries without cancer who died during the same period. Study Design We used multivariable regression analysis to estimate incremental per-person EOL cost after controlling for beneficiaries' age, race/ethnicity, sex, cancer site, and state of residence. Principal Findings End-of-life costs during the final 4 months of life were about $10,000 higher for Medicaid cancer patients than for those without cancer. Medicaid cancer patients are more intensive users of inpatient and ambulatory services than are Medicaid patients without cancer. Medicaid cancer patients who die soon after diagnosis have higher costs of care and use inpatient services more intensely than do Medicaid patients without cancer. Conclusions Medicaid cancer patients incur substantially higher EOL costs than noncancer patients. This increased cost may reflect the cost of palliative care. Future studies should assess the types and timing of services provided to Medicaid cancer patients at the EOL. PMID:25424134

  18. A methodology to investigate the intrinsic effect of the pulsed electric current during the spark plasma sintering of electrically conductive powders

    PubMed Central

    Locci, Antonio Mario; Cincotti, Alberto; Todde, Sara; Orrù, Roberto; Cao, Giacomo

    2010-01-01

    A novel methodology is proposed for investigating the effect of the pulsed electric current during the spark plasma sintering (SPS) of electrically conductive powders without potential misinterpretation of experimental results. First, ensemble configurations (geometry, size and material of the powder sample, die, plunger and spacers) are identified where the electric current is forced to flow only through either the sample or the die, so that the sample is heated either through the Joule effect or by thermal conduction, respectively. These ensemble configurations are selected using a recently proposed mathematical model of an SPS apparatus, which, once suitably modified, makes it possible to carry out detailed electrical and thermal analysis. Next, SPS experiments are conducted using the ensemble configurations theoretically identified. Using aluminum powders as a case study, we find that the temporal profiles of sample shrinkage, which indicate densification behavior, as well as the final density of the sample are clearly different when the electric current flows only through the sample or through the die containing it, whereas the temperature cycle and mechanical load are the same in both cases. PMID:27877354

  19. A comparison between three different pit and fissure sealants with regard to marginal integrity.

    PubMed

    Fernandes, Kristlee Sabrin; Chalakkal, Paul; de Ataide, Ida de Noronha; Pavaskar, Rajdeep; Fernandes, Precylia Philo; Soni, Harleen

    2012-04-01

    THE AIM OF THIS STUDY IS TO COMPARE THE OCCURRENCE OF ENAMEL FRACTURES, SEALANT FRACTURES AND MARGINAL FISSURES AFTER PLACEMENT OF THREE SEALANTS: Helioseal F, Conseal F and Clinpro. Thirty individuals between 13 and 15 years of age, diagnosed with pit and fissure caries by visual and DIAGNOdent examination, were chosen for sealant placement on their mandibular molars. The sealants were placed at random, after which, impressions were made with polyvinyl siloxane and casts were fabricated. Dies were prepared, each of which were sputter coated with gold in order to be examined under a scanning electron microscope. The following morphologies were analyzed from dies from each of the sealant groups: Continuous margins, sealant fractures, marginal fissures and enamel fractures. After six months, they were recalled for impression making. Dies were prepared and microscopically analyzed as mentioned. Based on the time of evaluation, there were two groups: Initial group (soon after placement) and final group (after six months). Statistical analysis was done using the paired 't' test and One-way analysis of variance (ANOVA). Clinpro had the greatest fracture resistance, followed by Conseal F and Helioseal F. The occurrence of marginal fissure was found to be least with Clinpro.

  20. A negative genetic interaction map in isogenic cancer cell lines reveals cancer cell vulnerabilities

    PubMed Central

    Vizeacoumar, Franco J; Arnold, Roland; Vizeacoumar, Frederick S; Chandrashekhar, Megha; Buzina, Alla; Young, Jordan T F; Kwan, Julian H M; Sayad, Azin; Mero, Patricia; Lawo, Steffen; Tanaka, Hiromasa; Brown, Kevin R; Baryshnikova, Anastasia; Mak, Anthony B; Fedyshyn, Yaroslav; Wang, Yadong; Brito, Glauber C; Kasimer, Dahlia; Makhnevych, Taras; Ketela, Troy; Datti, Alessandro; Babu, Mohan; Emili, Andrew; Pelletier, Laurence; Wrana, Jeff; Wainberg, Zev; Kim, Philip M; Rottapel, Robert; O'Brien, Catherine A; Andrews, Brenda; Boone, Charles; Moffat, Jason

    2013-01-01

    Improved efforts are necessary to define the functional product of cancer mutations currently being revealed through large-scale sequencing efforts. Using genome-scale pooled shRNA screening technology, we mapped negative genetic interactions across a set of isogenic cancer cell lines and confirmed hundreds of these interactions in orthogonal co-culture competition assays to generate a high-confidence genetic interaction network of differentially essential or differential essentiality (DiE) genes. The network uncovered examples of conserved genetic interactions, densely connected functional modules derived from comparative genomics with model systems data, functions for uncharacterized genes in the human genome and targetable vulnerabilities. Finally, we demonstrate a general applicability of DiE gene signatures in determining genetic dependencies of other non-isogenic cancer cell lines. For example, the PTEN−/− DiE genes reveal a signature that can preferentially classify PTEN-dependent genotypes across a series of non-isogenic cell lines derived from the breast, pancreas and ovarian cancers. Our reference network suggests that many cancer vulnerabilities remain to be discovered through systematic derivation of a network of differentially essential genes in an isogenic cancer cell model. PMID:24104479

  1. [Deferred consent for inclusion of patients unable to give their consent in studies in the field of emergency medicine].

    PubMed

    Kompanje, E J O; Jansen, T C; Le Noble, J L M L; de Geus, H R; Bakker, J

    2008-09-20

    Respect for individual autonomy, expressed in the concept of informed consent, is a basic principle in research with humans. Many patients in intensive care are unable to give consent because of mental incapacity, and this can be further complicated in emergency research, in which the treatment or experiment needs to be initiated without delay. In those situations consent can be deferred. Randomization is done without prior consent, followed by patients' or relatives' consent at a later stage. Butwhat should one do with the data if the patient dies at an early stage after randomization before consent could be obtained? Should the data be used or not? Should the relatives be asked for consent for using the data? The Dutch Central Committee on Research involving Human Subjects (CCMO) states that asking for consent after the patient has died makes no sense, because with the death of the patient the research has ended. Relatives do not have the authority to give consent for the use of medical data after the patient has died. Data can be used anonymously in the final analysis of the trial. We propose a flowchart for this procedure.

  2. Care at the Very End-of-Life: Dying Cancer Patients and Their Chosen Family’s Needs

    PubMed Central

    Clark, Katherine

    2017-01-01

    The majority of cancer deaths in countries such as Australia are predictable and most likely to occur in hospital. Despite this, hospitals remain challenged by providing the best care for this fragile cohort, often believing that care with palliative intent at the very end-of-life is not the best approach to care. Given the importance that dying patients place on excellent symptom control, failing to provide good end-of-life care is likely to be contrary to the wishes of the imminently dying patient and their family. This becomes even more significant when the impact of care on the bereavement outcomes of families is considered. Given the rising numbers of predicable hospital deaths, an urgent need to address this exists, requiring health professionals to be cognisant of specific care domains already identified as significant for both patients and those closest to them in knowledge, care and affection. This non-systematic review’s aims are to summarise the symptoms most feared by people imminently facing death which is defined as the terminal phase of life, where death is imminent and likely to occur within hours to days, or very occasionally, weeks. Further, this paper will explore the incidence and management of problems that may affect the dying person which are most feared by their family. The final section of this work includes a brief discussion of the most significant issues that require attention. PMID:28125017

  3. Feedback on end-of-life care in dementia: the study protocol of the FOLlow-up project.

    PubMed

    Boogaard, Jannie A; van Soest-Poortvliet, Mirjam C; Anema, Johannes R; Achterberg, Wilco P; Hertogh, Cees M P M; de Vet, Henrica C W; van der Steen, Jenny T

    2013-08-07

    End-of-life care in dementia in nursing homes is often found to be suboptimal. The Feedback on End-of-Life care in dementia (FOLlow-up) project tests the effectiveness of audit- and feedback to improve the quality of end-of-life care in dementia. Nursing homes systematically invite the family after death of a resident with dementia to provide feedback using the End-of-Life in Dementia (EOLD) - instruments. Two audit- and feedback strategies are designed and tested in a three-armed Randomized Controlled Trial (RCT): a generic feedback strategy using cumulative EOLD-scores of a group of patients and a patient specific feedback strategy using EOLD-scores on a patient level. A total of 18 nursing homes, three groups of six homes matched on size, geographic location, religious affiliation and availability of a palliative care unit were randomly assigned to an intervention group or the control group. The effect on quality of care and quality of dying and the barriers and facilitators of audit- and feedback in the nursing home setting are evaluated using mixed-method analyses. The FOLlow-up project is the first study to assess and compare the effect of two audit- and feedback strategies to improve quality of care and quality of dying in dementia. The results contribute to the development of practice guidelines for nursing homes to monitor and improve care outcomes in the realm of end-of-life care in dementia. The Netherlands National Trial Register (NTR). NTR3942.

  4. Final PSD Permit Extension Letter - Energy Answers Arecibo, LLC/Energy Answers Arecibo Puerto Rico Renewable Energy Project, PR

    EPA Pesticide Factsheets

    This page contains the Final PSD Permit Extension Letter for Energy Answers Arecibo Puerto Rico Renewable Energy Project, issued on April 10, 2017 and the EPA Public Announcement for Final PSD Permit Extension for Energy Answers Arecibo, PR.

  5. Use of robotics for nondestructive inspection of steel highway bridges and structures : final report.

    DOT National Transportation Integrated Search

    2005-01-01

    This report presents the results of a project to finalize and apply a crawling robotic system for the remote visual inspection of high-mast light poles. The first part of the project focused on finalizing the prototype crawler robot hardware and cont...

  6. Project Developmental Continuity Evaluation: Final Report. Appendices to Volume I.

    ERIC Educational Resources Information Center

    Bond, James T.; And Others

    This document provides the appendices for volume 1 of the final evaluation report of Project Developmental Continuity (PDC), a Head Start demonstration project initiated in 1974 to develop program models which enhance children's social competence by fostering developmental continuity from preschool through the early elementary grades.…

  7. Services for Children with Deaf-Blindness in Louisiana. Final Performance Report.

    ERIC Educational Resources Information Center

    Teddlie, Charles

    This final report describes activities and accomplishments of the Services for Children with Deaf-Blindness project, a 1-year federally supported project in Louisiana to improve identification and curriculum for these children by providing technical assistance and training to parents, school systems, and agency personnel. Project activities…

  8. Services for Children with Deaf-Blindness Pilot Project. Final Report.

    ERIC Educational Resources Information Center

    Stremel, Kathleen

    This final report describes a pilot project, "Quality Service Provision for Infants and Young Children with Deaf-Blindness: A Mechanism for State Intervention Teams," developed and implemented at the University of Southern Mississippi. The project developed a model of an intervention team that provides intensive training and technical…

  9. Interagency Planning and Support Project. Final Report.

    ERIC Educational Resources Information Center

    Salisbury, Christine

    This final report describes the activities and outcomes of a federally funded project designed to develop, implement, and evaluate a systemically oriented process model for improving the coordination of education and human services for young children with identified disabilities and their families at the local level. The project developed and used…

  10. The Early Childhood Interactive Technology Literacy Curriculum Project: A Final Report.

    ERIC Educational Resources Information Center

    Hutinger, Patricia; Robinsosn, Linda; Schneider, Carol; Johanson, Joyce

    This final report describes the activities and outcomes of the Interactive Technology Literacy Curriculum (ITLC) project. This federally funded 5-year model demonstration project was designed to advance the availability, quality, use and effectiveness of computer technology in addressing the acquisition of emergent literacy among young children…

  11. Project LEEDS: Leadership Education To Empower Disabled Students. Final Report.

    ERIC Educational Resources Information Center

    Aune, Betty; And Others

    This final report describes the activities of Project LEEDS (Leadership Education to Empower Disabled Students), a federally supported project designed to create student/staff teams from colleges and universities to encourage undergraduate/graduate students with disabilities to become leaders, through development of self-identity and identity with…

  12. High/Scope Outreach Project. Final Report. October 1, 1983-September 30, 1984.

    ERIC Educational Resources Information Center

    High/Scope Educational Research Foundation, Ypsilanti, MI.

    The final report reviews accomplishments of an outreach project designed to provide technical assistance and training to early childhood programs for handicapped children. The project features the Cognitively Oriented Preschool Curriculum, a developmental approach based on Piagetian theory and explained to build on the child's accomplishments. A…

  13. A Model Program for Hearing-Handicapped Infants Providing Medical, Academic, and Psychological Services (HI-MAPS). Final Report, July 1979-June 1982.

    ERIC Educational Resources Information Center

    Stein, Laszlo; Pien, Diana

    The document contains the final report of the HI-MAPS project, designed to develop a model program that would meet the medical, academic, and psychological needs of young hearing handicapped children, birth to 3 years, and their families in Chicago. An introductory section reviews project rationale, project philosophy, and overall project goals.…

  14. Career Awareness Program for Bilingual Haitian and Hispanic Students (Project CAP). Final Evaluation Report, 1993-94. OER Report.

    ERIC Educational Resources Information Center

    Roman, Elliott M.

    In 1993-94 the Career Awareness Program for Bilingual Haitian and Hispanic Students (Project CAP) was in its fifth and final year as an Elementary and Secondary Education Act Title VII project. Project CAP operated at two high schools in Brooklyn (New York), serving 136 Haitians at one and an undetermined number of Spanish-speaking and Haitian…

  15. How We Developed a Multidisciplinary Screening Project for People with Down's Syndrome Given the Increased Prevalence of Early Onset Dementia

    ERIC Educational Resources Information Center

    Jervis, Nicola; Prinsloo, Linda

    2008-01-01

    There has been much research that has identified an increased prevalence of Dementia in adults with Down's syndrome when compared with the general population. Neuropathological changes associated with Alzheimer's dementia in the brain have been found in most people with Down's syndrome who die over the age of 35 years. Given the limitations of…

  16. Performance and Reliability of Bonded Interfaces for High-Temperature Packaging. Annual Report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    DeVoto, Douglas

    2016-04-01

    Current generation automotive power electronics packages utilize silicon devices and lead-free solder alloys. To meet stringent technical targets for 2020 and beyond (for cost, power density, specific power, efficiency and reliability), wide-bandgap devices are being considered since they offer advantages such as operation at higher frequencies, voltages, and temperatures. Traditional power electronics packages must be redesigned to utilize the full potential of wide-bandgap devices, and the die- and substrate-attach layers are key areas where new material development and validation is required. Present solder alloys do not meet the performance requirements for these new package designs while also meeting cost andmore » hazardous substance restrictions. Sintered silver (Ag) promises to meet the needs for die- and substrate-attach interfaces but synthesis optimization and reliability evaluation must be completed. Sintered Ag material was proposed as an alternative solution in power electronics packages almost 20 years back. However, synthesis pressure requirements up 40 MPa caused a higher complexity in the production process and more stringent flatness specifications for the substrates. Recently, several manufacturers have developed sintered Ag materials that require lower (3-5 MPa) or even no bonding pressures. Degradation mechanisms for these sintered Ag materials are not well known and need to be addressed. We are addressing these aspects to some extent in this project. We are developing generalized (i.e., independent of geometry) stress intensity factor versus cycles-to-failure relations for sintered Ag. Because sintered Ag is a relatively new material for automotive power electronics, the industry currently does not have a good understanding of recommended synthesis parameters or expected reliability under prescribed conditions. It is an important deliverable of this project to transfer findings to industry to eliminate barriers to using sintered Ag as a viable and commercialized die- and substrate-attach material. Only a few manufacturers produce sintered Ag pastes and may consider some processing conditions as proprietary. It is the goal of this project to openly explore and define best practices in order to impact the maximum number of power electronics module manufacturers and suppliers.« less

  17. Scattering of electromagnetic plane wave from a perfect electric conducting strip placed at interface of topological insulator-chiral medium

    NASA Astrophysics Data System (ADS)

    Shoukat, Sobia; Naqvi, Qaisar A.

    2016-12-01

    In this manuscript, scattering from a perfect electric conducting strip located at planar interface of topological insulator (TI)-chiral medium is investigated using the Kobayashi Potential method. Longitudinal components of electric and magnetic vector potential in terms of unknown weighting function are considered. Use of related set of boundary conditions yields two algebraic equations and four dual integral equations (DIEs). Integrand of two DIEs are expanded in terms of the characteristic functions with expansion coefficients which must satisfy, simultaneously, the discontinuous property of the Weber-Schafheitlin integrals, required edge and boundary conditions. The resulting expressions are then combined with algebraic equations to express the weighting function in terms of expansion coefficients, these expansion coefficients are then substituted in remaining DIEs. The projection is applied using the Jacobi polynomials. This treatment yields matrix equation for expansion coefficients which is solved numerically. These unknown expansion coefficients are used to find the scattered field. The far zone scattering width is investigated with respect to different parameters of the geometry, i.e, chirality of chiral medium, angle of incidence, size of the strip. Significant effects of different parameters including TI parameter on the scattering width are noted.

  18. A summary of special coatings projects conducted in support of the Die Casting Program

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Selle, J.E.

    1988-09-12

    The usefulness of various kinds of coatings to the die casting program has been studied. This work includes heat transfer and fluid flow calculations, as well as experimental work, to examine the feasibility and characteristics of various types of coatings. Calculations include the effect of surface roughness on fluid flow, conductance as a function of coating thickness, conductivity as a function of coating porosity, and solidification and possible remelting of microspheres of metal. In each case, the model is described and the results are presented. Experimental work involved evaluating the relative insulating value of various coatings and an analysis ofmore » commercial flame-sprayed coatings, low-density coatings, and release coatings. In each case, description of the experimental arrangement is given and the results are described. 5 refs., 28 figs., 6 tabs.« less

  19. Development and evaluation of die and container materials. Low cost silicon solar array project

    NASA Technical Reports Server (NTRS)

    Wills, R. R.; Niesx, D. E.

    1979-01-01

    Specific compositions of high purity silicon aluminum oxynitride (Sialon) and silicon beryllium oxynitride (Sibeon) solid solutions were shown to be promising refractory materials for handling and manipulating solar grade silicon into silicon ribbon. Evaulation of the interaction of these materials in contact with molten silicon indicated that solid solutions based upon beta-Si3N4 were more stable than those based on Si2N2O. Sibeon was more resistant to molten silicon attack than Sialon. Both materials should preferably be used in an inert atmosphere rather than under vacuum conditions because removal of oxygen from the silicon melt occurs as SiO enhances the dissolution of aluminum and beryllium. The wetting angles of these materials were low enough for these materials to be considered as both die and container materials.

  20. Mud crab susceptibility to disease from white spot syndrome virus is species-dependent.

    PubMed

    Somboonna, Naraporn; Mangkalanan, Seksan; Udompetcharaporn, Attasit; Krittanai, Chartchai; Sritunyalucksana, Kallaya; Flegel, Tw

    2010-11-20

    Based on a report for one species (Scylla serrata), it is widely believed that mud crabs are relatively resistant to disease caused by white spot syndrome virus (WSSV). We tested this hypothesis by determining the degree of susceptibility in two species of mud crabs, Scylla olivacea and Scylla paramamosain, both of which were identified by mitochondrial 16 S ribosomal gene analysis. We compared single-dose and serial-dose WSSV challenges on S. olivacea and S. paramamosain. In a preliminary test using S. olivacea alone, a dose of 1 × 106 WSSV copies/g gave 100% mortality within 7 days. In a subsequent test, 17 S. olivacea and 13 S. paramamosain were divided into test and control groups for challenge with WSSV at 5 incremental, biweekly doses starting from 1 × 104 and ending at 5 × 106 copies/g. For 11 S. olivacea challenged, 3 specimens died at doses between 1 × 105 and 5 × 105 copies/g and none died for 2 weeks after the subsequent dose (1 × 106 copies/g) that was lethal within 7 days in the preliminary test. However, after the final challenge on day 56 (5 × 106 copies/g), the remaining 7 of 11 S. olivacea (63.64%) died within 2 weeks. There was no mortality in the buffer-injected control crabs. For 9 S. paramamosain challenged in the same way, 5 (55.56%) died after challenge doses between 1 × 104 and 5 × 105 copies/g, and none died for 2 weeks after the challenge dose of 1 × 106 copies/g. After the final challenge (5 × 106 copies/g) on day 56, no S. paramamosain died during 2 weeks after the challenge, and 2 of 9 WSSV-infected S. paramamosain (22.22%) remained alive together with the control crabs until the end of the test on day 106. Viral loads in these survivors were low when compared to those in the moribund crabs. S. olivacea and S. paramamosain show wide variation in response to challenge with WSSV. S. olivacea and S. paramamosain are susceptible to white spot disease, and S. olivacea is more susceptible than S. paramamosain. Based on our single-challenge and serial challenge results, and on previous published work showing that S. serrata is relatively unaffected by WSSV infection, we propose that susceptibility to white spot disease in the genus Scylla is species-dependent and may also be dose-history dependent. In practical terms for shrimp farmers, it means that S. olivacea and S. paramamosain may pose less threat as WSSV carriers than S. serrata. For crab farmers, our results suggest that rearing of S. serrata would be a better choice than S. paramamosain or S. olivacea in terms of avoiding losses from seasonal outbreaks of white spot disease.

  1. Tech Prep II: Implementation Final Report.

    ERIC Educational Resources Information Center

    Brown, Jane A.

    This document contains the final progress report on a tech prep implementation project and the Work Force Challenge 2000 Report developed during the project. The final report lists these major accomplishments: approximately 1,500 educators in grades K-12 were provided information concerning future global issues in the work force and the effects in…

  2. The risk of death by age, sex, and smoking status in the United States: putting health risks in context.

    PubMed

    Woloshin, Steven; Schwartz, Lisa M; Welch, H Gilbert

    2008-06-18

    To make sense of the disease risks they face, people need basic facts about the magnitude of a particular risk and how one risk compares with other risks. Unfortunately, this fundamental information is not readily available to patients or physicians. We created simple one-page charts that present the 10-year chance of dying from various causes according to age, sex, and smoking status. We used the National Center for Health Statistics Multiple Cause of Death Public Use File for 2004 and data from the 2004 US Census to calculate age- and sex-specific death rates for various causes of death. We then combined data on smoking prevalence (from the National Health Interview Survey) and the relative risks of death from various causes for smokers vs never smokers (from the American Cancer Society's Cancer Prevention Study-II) to determine age-, sex-, and smoking-specific death rates. Finally, we accumulated these risks for various starting ages in a series of 10-year life tables. The charts present the 10-year risks of dying from heart disease; stroke; lung, colon, breast, cervical, ovarian, and prostate cancer; pneumonia; influenza; AIDS; chronic obstructive pulmonary disease; accidents; and all causes. At all ages, the 10-year risk of death from all causes combined is higher for men than women. The effect of smoking on the chance of dying is similar to the effect of adding 5 to 10 years of age: for example, a 55-year-old man who smokes has about the same 10-year risk of death from all causes as a 65-year-old man who never smoked (ie, 178 vs 176 of 1000 men, respectively). For men who never smoked, heart disease death represents the single largest cause of death from age 50 on and the chance of dying from heart disease exceeds the chances of dying from lung, colon, and prostate cancers combined at every age. For men who currently smoke, the chance of dying from lung cancer is of the same order of magnitude as the chance dying from heart disease and after age 50 it is about 10 times greater than the chance of dying from prostate or colon cancer. For women who have never smoked, the magnitudes of the 10-year risks of death from breast cancer and heart disease are similar until age 60; from this age on, heart disease represents the single largest cause of death. For women who currently smoke, the chance of dying from heart disease or lung cancer exceeds the chance of dying from breast cancer from age 40 on (and does so by at least a factor of 5 after age 55). The availability of simple charts with consistent data presentations of important causes of death may facilitate discussion about disease risk between physicians and their patients and help highlight the dangers of smoking.

  3. The Risk of Death by Age, Sex, and Smoking Status in the United States: Putting Health Risks in Context

    PubMed Central

    Woloshin, Steven; Welch, H. Gilbert

    2008-01-01

    Background To make sense of the disease risks they face, people need basic facts about the magnitude of a particular risk and how one risk compares with other risks. Unfortunately, this fundamental information is not readily available to patients or physicians. We created simple one-page charts that present the 10-year chance of dying from various causes according to age, sex, and smoking status. Methods We used the National Center for Health Statistics Multiple Cause of Death Public Use File for 2004 and data from the 2004 US Census to calculate age- and sex-specific death rates for various causes of death. We then combined data on smoking prevalence (from the National Health Interview Survey) and the relative risks of death from various causes for smokers vs never smokers (from the American Cancer Society’s Cancer Prevention Study-II) to determine age-, sex-, and smoking-specific death rates. Finally, we accumulated these risks for various starting ages in a series of 10-year life tables. The charts present the 10-year risks of dying from heart disease; stroke; lung, colon, breast, cervical, ovarian, and prostate cancer; pneumonia; influenza; AIDS; chronic obstructive pulmonary disease; accidents; and all causes. Results At all ages, the 10-year risk of death from all causes combined is higher for men than women. The effect of smoking on the chance of dying is similar to the effect of adding 5 to 10 years of age: for example, a 55-year-old man who smokes has about the same 10-year risk of death from all causes as a 65-year-old man who never smoked (ie, 178 vs 176 of 1000 men, respectively). For men who never smoked, heart disease death represents the single largest cause of death from age 50 on and the chance of dying from heart disease exceeds the chances of dying from lung, colon, and prostate cancers combined at every age. For men who currently smoke, the chance of dying from lung cancer is of the same order of magnitude as the chance dying from heart disease and after age 50 it is about 10 times greater than the chance of dying from prostate or colon cancer. For women who have never smoked, the magnitudes of the 10-year risks of death from breast cancer and heart disease are similar until age 60; from this age on, heart disease represents the single largest cause of death. For women who currently smoke, the chance of dying from heart disease or lung cancer exceeds the chance of dying from breast cancer from age 40 on (and does so by at least a factor of 5 after age 55). Conclusion The availability of simple charts with consistent data presentations of important causes of death may facilitate discussion about disease risk between physicians and their patients and help highlight the dangers of smoking. PMID:18544745

  4. Instructional Systems Development Model for Interactive Videodisc. Final Report.

    ERIC Educational Resources Information Center

    Campbell, J. Olin; And Others

    This third and final report on a 3-year project, which developed authoring and production procedures for interactive videodisc based on the Interservice Procedures for Instructional Systems Development (IPISD), reviews the current state of the art, provides an overview of the project, and describes two videodiscs made for the project and the…

  5. Information Technology Team Projects in Higher Education: An International Viewpoint

    ERIC Educational Resources Information Center

    Lynch, Kathy; Heinze, Aleksej; Scott, Elsje

    2007-01-01

    It is common to find final or near final year undergraduate Information Technology students undertaking a substantial development project; a project where the students have the opportunity to be fully involved in the analysis, design, and development of an information technology service or product. This involvement has been catalyzed and prepared…

  6. Project Developmental Continuity Evaluation: Final Report. Volume II: The Process of Program Implementation in PDC.

    ERIC Educational Resources Information Center

    Wacker, Sally; And Others

    The second of two volumes, this document continues the final evaluation report of Project Developmental Continuity (PDC), a Head Start demonstration project initiated in 1974 to develop program models which enhance children's social competence by fostering developmental continuity from preschool through the early elementary grades. In particular,…

  7. Faculty College. Final Project Report, July 1, 1976 through June 30, 1978.

    ERIC Educational Resources Information Center

    Wisconsin Univ., Oshkosh.

    The final report of a faculty development project, sponsored by the Fund for the Improvement of Postsecondary Education, is presented. Project objectives were to: augment the existing Faculty College programming with special focus sessions, featuring national leaders who would treat issues in one of the developing areas of the institution; bring…

  8. Project Target: Criterion-Referenced Physical Fitness Standards for Adolescents with Disabilities. Final Report.

    ERIC Educational Resources Information Center

    Winnick, Joseph P.; Short, Francis X.

    This final report discusses the outcomes of a project designed to extend the nation's current emphasis on health-related, criterion-referenced fitness testing and programming to children and adolescents with disabilities. It summarizes project activities leading up to the Brockport Physical Fitness Test and related measures. Activities included:…

  9. 75 FR 21342 - Notice of Availability of the Final Environmental Impact Statement for the Mona to Oquirrh...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-23

    ... Corridor Project, Utah, and the Proposed Pony Express Resource Management Plan Amendment AGENCY: Bureau of...)/Proposed Resource Management Plan Amendment (RMPA) for the Mona to Oquirrh Transmission Corridor Project... Final EIS/Proposed RMPA for the Mona to Oquirrh Transmission Corridor Project have been sent to affected...

  10. Selection and Validation of Model Early Childhood Projects: Final Report.

    ERIC Educational Resources Information Center

    Stock, John R.; And Others

    Presented is the final report of a research program to select and describe outstanding Handicapped Children's Early Education Program (HCEEP) projects. Projects were analyzed in terms of 14 components of an HCEEP program (such as screening, programing, and inservice training). A detailed discussion of model selection and validation is appendixed.)…

  11. Science and Engineering Technician Curriculum Development Project. Final Report.

    ERIC Educational Resources Information Center

    Mowery, Donald R.; Wolf, Lawrence J.

    Project SET (Science and Engineering for Technicians) developed a series of study guides designed to teach generic science and engineering skills to students interested in becoming technicians. An entire 2-year curriculum is encompassed by these guides, geared for 2-year college students. Described in this final report are the project's rationale,…

  12. The Trine Project Final Report.

    ERIC Educational Resources Information Center

    Gunderson, Jon R.; And Others

    The final report describes the Trine Project which addressed three needs in the education of handicapped children: the need for an alternate writing system, the need for communication, and the need for access to general purpose computers used in the schools. The project had three major objectives: (1) to design a low-cost portable writing and…

  13. CBSS Outreach Project: Computer-Based Study Strategies for Students with Learning Disabilities. Final Report.

    ERIC Educational Resources Information Center

    Anderson-Inman, Lynne; Ditson, Mary

    This final report describes activities and accomplishments of the four-year Computer-Based Study Strategies (CBSS) Outreach Project at the University of Oregon. This project disseminated information about using computer-based study strategies as an intervention for students with learning disabilities and provided teachers in participating outreach…

  14. The Choctaw Home-Centered Family Education Demonstration Project. Final Report.

    ERIC Educational Resources Information Center

    Quigley, Patrick A.; And Others

    The final report of the four-year (1972-1976) Choctaw Family Education Project identifies the major goal, "to demonstrate a workable early childhood model for rural reservation groups," and consists of an executive summary, a comprehensive report, and a personalized report. Objectives of the project, carried out in 6 Choctaw reservation…

  15. Cooperative Program Improvement; An Experiment in ABE In-Service Training. Doolittle Family Education Center Experimental In-Service Training Project. Final Report.

    ERIC Educational Resources Information Center

    Griffith, William S.; And Others

    This document, consisting of seven chapters and 12 appendixes, is a full final report of the Doolittle Family Education Center Experimental In-Service Training Project. Chapter II consists of the history and plan of the project including an explanation of the framework of the model that was used to conceptualize the project. Chapter III is a…

  16. Choosing Optional Infused Career Education for Students in High School Bilingual Programs (Project CHOICE). Final Evaluation Report 1992-93. OREA Report.

    ERIC Educational Resources Information Center

    Cantalupo, Denise

    Project CHOICE was an Elementary and Secondary Education Act Title VII-funded project in its fifth and final year of operation at Fort Hamilton High School in Brooklyn and Springfield Gardens High School in Queens (both in New York City). In 1992-93 the project served 364 students of limited English proficiency. Participants received instruction…

  17. Special Education Teacher Computer Literacy Training. Project STEEL. A Special Project To Develop and Implement a Computer-Based Special Teacher Education and Evaluation Laboratory. Volume II. Final Report.

    ERIC Educational Resources Information Center

    Frick, Theodore W.; And Others

    The document is part of the final report on Project STEEL (Special Teacher Education and Evaluation Laboratory) intended to extend the utilization of technology in the training of preservice special education teachers. This volume focuses on the second of four project objectives, the development of a special education teacher computer literacy…

  18. Interactive Peer Coaching/Mentoring Project for Preparing Teachers of Students with Severe Behavioral Disorders Final Report. Volume 1: Project Narrative and Briefing Papers [and] Volume 2: Appendices.

    ERIC Educational Resources Information Center

    North Dakota Center for Persons with Disabilities, Minot.

    This final report discusses the activities and outcomes of the Interactive Peer Coaching/Mentoring (IPCM) Project, a program designed to prepare teachers of students with severe behavioral disorders (SED) residing in a rural, remote area in North Dakota. The IPCM project was conducted from July 1997 through July 2000 and developed an…

  19. Temporal changes in blood variables during final maturation and senescence in male sockeye salmon Oncorhynchus nerka: reduced osmoregulatory ability can predict mortality.

    PubMed

    Jeffries, K M; Hinch, S G; Donaldson, M R; Gale, M K; Burt, J M; Thompson, L A; Farrell, A P; Patterson, D A; Miller, K M

    2011-08-01

    This study is the first to characterize temporal changes in blood chemistry of individuals from one population of male sockeye salmon Oncorhynchus nerka during the final 6 weeks of sexual maturation and senescence in the freshwater stage of their spawning migration. Fish that died before the start of their historic mean spawning period (c. 5 November) were characterized by a 20-40% decrease in plasma osmolality, chloride and sodium, probably representing a complete loss of osmoregulatory ability. As fish became moribund, they were further characterized by elevated levels of plasma cortisol, lactate and potassium. Regressions between time to death and plasma chloride (8 October: P < 0·001; 15 October: P < 0·001) indicate that plasma chloride was a strong predictor of longevity in O. nerka. That major plasma ion levels started to decline 2-10 days (mean of 6 days) before fish became moribund, and before other stress, metabolic or reproductive hormone variables started to change, suggests that a dysfunctional osmoregulatory system may initiate rapid senescence and influence other physiological changes (i.e. elevated stress and collapsed reproductive hormones) which occur as O. nerka die on spawning grounds. © 2011 The Authors. Journal of Fish Biology © 2011 The Fisheries Society of the British Isles.

  20. Acute cardiovascular toxicity of sterilizers, PHMG, and PGH: severe inflammation in human cells and heart failure in zebrafish.

    PubMed

    Kim, Jae-Yong; Kim, Hak Hyeon; Cho, Kyung-Hyun

    2013-06-01

    In 2011, dozens of children and pregnant women in Korea died by exposure to sterilizer for household humidifier, such as Oxy(®) and Cefu(®). Until now, however, it remains unknown how the sterilizer affect the human health to cause the acute deaths. To find its toxicity for organ, we investigated the putative toxicity of the sterilizer in the cardiovascular system. The sterilizers, polyhexamethylene guanidine phosphate (PHMG, Cefu(®)), and oligo-[2-(2-ethoxy)-ethoxyethyl)-guanidinium-chloride (PGH, Oxy(®)) were treated to human lipoproteins, macrophages, and dermal fibroblast cells. The PGH and PHMG at normal dosages caused severe atherogenic process in human macrophages, cytotoxic effect, and aging in human dermal cell. Zebrafish embryos, which were exposed to the sterilizer, showed early death with acute inflammation and attenuated developmental speed. All zebrafish exposed to the working concentration of PHMG (final 0.3 %) and PGH (final 10 mM) died within 70 min and displayed acute increases in serum triacylglycerol level and fatty liver induction. The dead zebrafish showed severe accumulation of fibrous collagen in the bulbous artery of the heart with elevation of reactive oxygen species. In conclusion, the sterilizers showed acute toxic effect in blood circulation system, causing by severe inflammation, atherogenesis, and aging, with embryo toxicity.

  1. Tree-ring δ13C and δ18O, leaf δ13C and wood and leaf N status demonstrate tree growth strategies and predict susceptibility to disturbance

    PubMed Central

    Billings, S.A.; Boone, A.S.; Stephen, F.M.

    2016-01-01

    Understanding how tree growth strategies may influence tree susceptibility to disturbance is an important goal, especially given projected increases in diverse ecological disturbances this century. We use growth responses of tree rings to climate, relationships between tree-ring stable isotopic signatures of carbon (δ13C) and oxygen (δ18O), wood nitrogen concentration [N], and contemporary leaf [N] and δ13C values to assess potential historic drivers of tree photosynthesis in dying and apparently healthy co-occurring northern red oak (Quercus rubra L. (Fagaceae)) during a region-wide oak decline event in Arkansas, USA. Bole growth of both healthy and dying trees responded negatively to drought severity (Palmer Drought Severity Index) and temperature; healthy trees exhibited a positive, but small, response to growing season precipitation. Contrary to expectations, tree-ring δ13C did not increase with drought severity. A significantly positive relationship between tree-ring δ13C and δ18O was evident in dying trees (P < 0.05) but not in healthy trees. Healthy trees’ wood exhibited lower [N] than that of dying trees throughout most of their lives (P < 0.05), and we observed a significant, positive relationship (P < 0.05) in healthy trees between contemporary leaf δ13C and leaf N (by mass), but not in dying trees. Our work provides evidence that for plants in which strong relationships between δ13C and δ18O are not evident, δ13C may be governed by plant N status. The data further imply that historic photosynthesis in healthy trees was linked to N status and, perhaps, C sink strength to a greater extent than in dying trees, in which tree-ring stable isotopes suggest that historic photosynthesis was governed primarily by stomatal regulation. This, in turn, suggests that assessing the relative dominance of photosynthetic capacity vs stomatal regulation as drivers of trees’ C accrual may be a feasible means of predicting tree responses to some disturbance events. Our work demonstrates that a dual isotope, tree-ring approach can be integrated with tree N status to begin to unravel a fundamental question in forest ecology: why do some trees die during a disturbance, while other conspecifics with apparently similar access to resources remain healthy? PMID:26960389

  2. Misstaging in nephroblastoma. Causes and consequences. A report of the Sixth Nephroblastoma Trial and Study of the International Society of Paediatric Oncology.

    PubMed

    de Kraker, J; Delemarre, J F; Lilien, M R; Tournade, M F

    1999-06-01

    In the Wilms tumour trials and studies of the International Society of Paediatric Oncology (SIOP), the postoperative treatment is based on the extension (stage) and the histological type. Incorrect staging results in under- or overtreatment. The authors studied the causes and consequences of misstaging in SIOP 6. In this study, the final stage was defined by a central panel of pathologists after review of the surgical and histopathological forms and study of representative microscopical sections. In 46 out of 509 trial patients there was a discrepancy between the final stage and the stage determined at the participating centres: 33 patients were understaged of whom 27 survived more than 5 years (18% died) and 13 patients were overstaged of whom 11 survived more than 5 years (15.3% died). All children with tumour extension into the renal pelvis and treated as stage I instead of stage II survived without evidence of disease. Therefore, it was decided to treat these children in the next study as a stage I. In 17 cases the treatment was based on the surgical stage before the pathological stage was known or the treatment was given according to the stage determined by the local pathologist without waiting for the panel review. The numbers are too small to conclude on the consequences of overtreatment on late effects. For all clinicians the main and most important conclusion of this study is: wait for the final pathology report before initiating postoperative therapy.

  3. Looking for the Self: Phenomenology, Neurophysiology and Philosophical Significance of Drug-induced Ego Dissolution

    PubMed Central

    Millière, Raphaël

    2017-01-01

    There is converging evidence that high doses of hallucinogenic drugs can produce significant alterations of self-experience, described as the dissolution of the sense of self and the loss of boundaries between self and world. This article discusses the relevance of this phenomenon, known as “drug-induced ego dissolution (DIED)”, for cognitive neuroscience, psychology and philosophy of mind. Data from self-report questionnaires suggest that three neuropharmacological classes of drugs can induce ego dissolution: classical psychedelics, dissociative anesthetics and agonists of the kappa opioid receptor (KOR). While these substances act on different neurotransmitter receptors, they all produce strong subjective effects that can be compared to the symptoms of acute psychosis, including ego dissolution. It has been suggested that neuroimaging of DIED can indirectly shed light on the neural correlates of the self. While this line of inquiry is promising, its results must be interpreted with caution. First, neural correlates of ego dissolution might reveal the necessary neurophysiological conditions for the maintenance of the sense of self, but it is more doubtful that this method can reveal its minimally sufficient conditions. Second, it is necessary to define the relevant notion of self at play in the phenomenon of DIED. This article suggests that DIED consists in the disruption of subpersonal processes underlying the “minimal” or “embodied” self, i.e., the basic experience of being a self rooted in multimodal integration of self-related stimuli. This hypothesis is consistent with Bayesian models of phenomenal selfhood, according to which the subjective structure of conscious experience ultimately results from the optimization of predictions in perception and action. Finally, it is argued that DIED is also of particular interest for philosophy of mind. On the one hand, it challenges theories according to which consciousness always involves self-awareness. On the other hand, it suggests that ordinary conscious experience might involve a minimal kind of self-awareness rooted in multisensory processing, which is what appears to fade away during DIED. PMID:28588463

  4. Early and late signs that precede dying among older persons in nursing homes: the multidisciplinary team's perspective.

    PubMed

    Åvik Persson, Helene; Sandgren, Anna; Fürst, Carl-Johan; Ahlström, Gerd; Behm, Lina

    2018-06-04

    Nursing home residents in Sweden are old, frail and usually have multiple morbidities which often make dying a prolonged suffering. It has been found that older persons at nursing homes receive far less palliative care than younger persons, partly because it is difficult to identify when the final stage of life begins. The identification may help the staff to enable the older person and their families to participate in planning the care in accordance with their own preferences and values. With this in mind the aim was to explore the experiences of early and late signs preceding dying in older persons in nursing homes from the multidisciplinary team's perspective. The focus group method was used to interview 20 health-care professionals on the basis of semi-structured questions. Four focus groups were conducted at four nursing homes in two counties in southern Sweden. The groups included different professionals such as assistant nurses, registered nurses, occupational therapists, physiotherapists, social workers and unit managers. The analysis was conducted according to the focus group method developed by Kruger and Casey. The analysis revealed one major theme, from unawareness to obviousness, which illustrates that the participants experienced dying as a happening, not a process, and found it difficult to identify early signs. Even though it was a new way of thinking, several suggestions of early signs were presented. The main category "Going into a bubble" illustrates early signs, which meant that the older person showed signs of wanting to withdraw from the outside world. The main category "The body begins to shut down" illustrates late signs, which meant that the older person showed signs that indicate that the body starts to prepare for death. This study conveys new knowledge concerning the multidisciplinary team's collective experience of early and late signs that precede dying. This knowledge can increase the understanding of when a palliative care approach needs to be in place at nursing homes. The use of a palliative care approach in care planning requires consensus in the perception of the dying process of frail older persons.

  5. The Midlands Consortium Star Schools Project: Final Report, Final Evaluation Report, Final Evaluation Report Appendices.

    ERIC Educational Resources Information Center

    Midlands Consortium.

    The reports presented in this document describe the results of the first 2 years of the Midlands Consortium Star Schools Project (MCSSP) (October 1, 1988-December 31, 1990). The first report summarizes the major accomplishments of the MCSSP, including: (1) the installation of communications satellites at schools in Alabama, Kansas, Mississippi,…

  6. 75 FR 19168 - Federal Acquisition Regulation; FAR Case 2009-005, Use of Project Labor Agreements for Federal...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-13

    ... located on Indian reservations. Response: GSA, DoD, and NASA have clarified in the final rule that project... Administration (GSA), and National Aeronautics and Space Administration (NASA). ACTION: Final rule. SUMMARY: GSA, DOD, and NASA are issuing a final rule amending the Federal Acquisition Regulation (FAR) to implement...

  7. KSC-2014-3640

    NASA Image and Video Library

    2014-08-29

    CAPE CANAVERAL, Fla. -- From left, Kennedy Space Center Director Bob Cabana, Kenneth Cameron, and Jon McBride, all former NASA astronauts, pause for reflection after placing a wreath honoring former NASA astronaut Steven R. Nagel at the Space Shuttle Atlantis exhibit at the Kennedy Space Center Visitor Complex in Florida. Nagel died Aug. 21 after a long illness. He was 67 years old. Nagel served as a mission specialist on his first space shuttle flight, STS-51G, in 1985. He was pilot on his second shuttle flight, STS-61A, also in 1985. He commanded his final two flights, STS-37 and STS-55, in 1991 and 1993, respectively. He logged a total of 723 hours in space. To learn more about Nagel's career, visit http://www.nasa.gov/press/2014/august/former-nasa-astronaut-steven-nagel-veteran-of-four-shuttle-flights-dies-at-67/. Photo credit: NASA/Dimitri Gerondidakis

  8. Development of a Secondary School Physics Program: Harvard Project Physics. Volume 2, More Appendices. Final Report.

    ERIC Educational Resources Information Center

    Holton, Gerald; And Others

    As appendices to the final report on Project Physics (SE 015 500), this volume includes parts of the original documents concerning the project development. Articles published in the "Physics Teacher" are included in reprint form. Evaluation and research papers along with related materials issued in other publications are grouped into…

  9. Building a Network of Services: 1963-1971. Final Report: Greater Cleveland Mental Retardation Development Project.

    ERIC Educational Resources Information Center

    Buckman, Rilma Oxley

    The final report documents the Greater Cleveland Mental Retardation Development Project, a 5-year demonstration project concerned with solving such problems as how a community can provide all the services and programs needed by the retarded and their families, ensure successful and appropriate employment, and staff and finance such programs.…

  10. Classrooms beyond School Walls for Grades K-12. Mamaroneck Career Education Project. Final Report.

    ERIC Educational Resources Information Center

    Mamaroneck Union Free School District 1, NY.

    This document contains two reports on the Classrooms beyond Walls Career Education Project conducted by the Mamaroneck Union Free School District and the Sound Consortium for grades K-12 in the 1975-76 school year. The final report summarizes the project's major objectives (increasing self-awareness and decision-making skills, training teachers in…

  11. Two Different Approaches to Teaching Final-Year Projects for Mechanical Engineers and Biotechnologists at Ngee Ann Polytechnic--Case Studies Approach.

    ERIC Educational Resources Information Center

    Walsh, Kath; Rebaczonok-Padulo, Michael

    1993-01-01

    Ngee Ann Polytechnic, a leading postsecondary technical institution in Singapore, offers English for academic and occupational purposes to prepare students for writing their final year projects. This article discusses the approaches used in Mechanical Engineering and Biotechnology projects. A sample exercise is appended. (Contains two references.)…

  12. 75 FR 69433 - Public Utility District No. 1 of Snohomish County, WA; Notice of Availability of Final...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-12

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Project No. 2157-188] Public Utility District No. 1 of Snohomish County, WA; Notice of Availability of Final Environmental Assessment November 4... Hydroelectric Project (FERC Project No. 2157-188), located on the Sultan River 20 miles east of the city of...

  13. Final report: Compiled MPI. Cost-Effective Exascale Application Development

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gropp, William Douglas

    2015-12-21

    This is the final report on Compiled MPI: Cost-Effective Exascale Application Development, and summarizes the results under this project. The project investigated runtime enviroments that improve the performance of MPI (Message-Passing Interface) programs; work at Illinois in the last period of this project looked at optimizing data access optimizations expressed with MPI datatypes.

  14. 75 FR 63503 - Notice of Availability of Final Environmental Impact Statement for the Solar Millennium, Amargosa...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-15

    ... for the Solar Millennium, Amargosa Farm Road Solar Power Project, Nye County, NV AGENCY: Bureau of... Amargosa Farm Road Solar Power Project, Nye County, Nevada, and by this notice is announcing its availability. DATES: The BLM will not issue a final decision on the Amargosa Farm Road Solar Power Project for...

  15. Through Shared Windows: Outreach Project for Infants, Toddlers, and Children with Developmental Disabilities. Final Report.

    ERIC Educational Resources Information Center

    Harrison, Holly

    This final report describes activities and accomplishments of the Through Shared Windows (TSW) Outreach Project, a 4-year project at the University of New Mexico designed to improve services to young children with disabilities and their families. Three major outcomes were accomplished. First, a Web site was developed that focuses on observational…

  16. 75 FR 51479 - Notice of Availability of the Final Environmental Impact Statement for the Chevron Energy...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-20

    ... (EIS) for the Chevron Energy Solutions/Solar Millennium (CESSM), LLC's Blythe Solar Power Plant (BSPP... project and amend the CDCA Plan to prohibit solar energy projects on the project site. The BLM will take..., LVRWB09B2600] Notice of Availability of the Final Environmental Impact Statement for the Chevron Energy...

  17. Partnering with Environmental Agencies and Communities to Pilot Use of the Environmental Justice Screening Method (EJSM) Cumulative Impacts Tool

    EPA Science Inventory

    Summary: This is the final report of a 24-month research project. This project was awarded as a $75,000.00 cooperative agreement to Occidental College. The project began on 1 September 2012, following final approval of the funding request package by the EPA Grants Office (US E...

  18. 40. From Final Construction Report on the Haleakala Road ProjectNR7, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    40. From Final Construction Report on the Haleakala Road Project--NR-7, Hawaii National Park, Island of Maui, Territory of Hawaii, T.H. GENERAL VIEW OT THE PROJECT SHOWING CONSPICUOUS SCARS. THE BEFORE PHOTO OF A BEFORE AND AFTER SET. AFTER PHOTO IS HI-52-41. - Haleakala National Park Roads, Pukalani, Maui County, HI

  19. The Elder Abuse Prevention Project, Phase Two, Three and Four. Final Report.

    ERIC Educational Resources Information Center

    Regina Univ. (Saskatchewan). Univ. Extension. Seniors Education Centre.

    This document presents the final report from an educational and community development program designed to raise awareness about the abuse and neglect of the elderly. The Elder Abuse Prevention Project is briefly described in terms of project goals, objectives, the model used, the target groups served, and the evaluation processes employed. It is…

  20. Health for All. Project WHERE (World Health Education Resources Exchange). Field Tested and Revised. Teenage Health Teaching Modules.

    ERIC Educational Resources Information Center

    American Association for World Health, Washington, DC.

    Every two seconds somewhere in the world a child dies from a preventable disease. Millions lack access to safe drinking water. Smoking, alcoholism, and drug abuse are on the increase in developing nations. In the United States, experts estimate that one out of every ten people, a majority of them women and children, go to bed hungry, and the…

  1. RESEARCH FOR MANAGING URBAN WATERSHED MICROBIAL CONTAMINATION (PROJECT 1: MANAGING URBAN WATERSHED PATHOGEN CONTAMINATION: 2. EFFECT OF LAND USE AND SEASON ON MICROORGANISM CONCENTRATION ON URBAN STORMWATER RUNOFF; 3. MICROORGANISM DIE-OFF RATES UNDER VARIOUS CONDITIONS.

    EPA Science Inventory

    The Water Supply and Water Resources Division (WSWRD) developed a document entitled Managing Urban Watershed Pathogen Contamination (EPA 600/R-03/111). This document provides information to support specific steps of the total maximum daily load (TMDL) process for meeting water q...

  2. Zachary-Fort Lauderdale pipeline construction and conversion project: final supplement to final environmental impact statement. Docket No. CP74-192

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    None

    This Final Supplement to the Final Environmental Impact Statement (Final Supplement) evaluates the economic, engineering, and environmental aspects of newly developed alternatives to an abandonment/conversion project proposed by Florida Gas Transmission Company (Florida Gas). It also updates the staff's previous FEIS and studies revisions to the original proposal. Wherever possible, the staff has adopted portions of its previous FEIS in lieu of reprinting portions of that analysis which require no change. 60 references, 8 figures, 35 tables.

  3. 38. From Final Construction Report on the Haleakala Road ProjectNR7, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    38. From Final Construction Report on the Haleakala Road Project--NR-7, Hawaii National Park, Island of Maui, Territory of Hawaii. BRIDGE AT STATION 85+. - Haleakala National Park Roads, Pukalani, Maui County, HI

  4. On the design of learning outcomes for the undergraduate engineer's final year project

    NASA Astrophysics Data System (ADS)

    Thambyah, Ashvin

    2011-03-01

    The course for the final year project for engineering students, because of its strongly research-based, open-ended format, tends to not have well defined learning outcomes, which are also not aligned with any accepted pedagogical philosophy or learning technology. To address this problem, the revised Bloom's taxonomy table of Anderson and Krathwohl (2001) is utilised, as suggested previously by Lee and Lai (2007), to design new learning outcomes for the final year project course in engineering education. Based on the expectations of the engineering graduate, and integrating these graduate expectations into the six cognitive processes and four knowledge dimensions of the taxonomy table, 24 learning outcomes have been designed. It is proposed that these 24 learning outcomes be utilised as a suitable working template to inspire more critical evaluation of what is expected to be learnt by engineering students undertaking final year research or capstone projects.

  5. Qualification and Reliability for MEMS and IC Packages

    NASA Technical Reports Server (NTRS)

    Ghaffarian, Reza

    2004-01-01

    Advanced IC electronic packages are moving toward miniaturization from two key different approaches, front and back-end processes, each with their own challenges. Successful use of more of the back-end process front-end, e.g. microelectromechanical systems (MEMS) Wafer Level Package (WLP), enable reducing size and cost. Use of direct flip chip die is the most efficient approach if and when the issues of know good die and board/assembly are resolved. Wafer level package solve the issue of known good die by enabling package test, but it has its own limitation, e.g., the I/O limitation, additional cost, and reliability. From the back-end approach, system-in-a-package (SIAP/SIP) development is a response to an increasing demand for package and die integration of different functions into one unit to reduce size and cost and improve functionality. MEMS add another challenging dimension to electronic packaging since they include moving mechanical elements. Conventional qualification and reliability need to be modified and expanded in most cases in order to detect new unknown failures. This paper will review four standards that already released or being developed that specifically address the issues on qualification and reliability of assembled packages. Exposures to thermal cycles, monotonic bend test, mechanical shock and drop are covered in these specifications. Finally, mechanical and thermal cycle qualification data generated for MEMS accelerometer will be presented. The MEMS was an element of an inertial measurement unit (IMU) qualified for NASA Mars Exploration Rovers (MERs), Spirit and Opportunity that successfully is currently roaring the Martian surface

  6. Does the availability of hospital beds affect utilization patterns? The case of end-of-life care.

    PubMed

    Wilson, D M; Truman, C D

    2001-11-01

    Hospital downsizing in Canada during the 1990s raised public concern over the availability of hospital care, in addition to heightening administrative interest in improving or maximizing hospital utilization. One ongoing concern about hospital utilization is that a disproportionately large share of hospital resources is used by terminally ill and dying people. A research study using 1992/1993-1996/1997 in-patient abstracts data for the province of Alberta, Canada, was undertaken to explore and describe hospital utilization by dying in-patients. This investigation found only 48.2% of all deaths in Alberta over the five years studied involved hospital in-patients. An 18.5% reduction in the number of in-patient deaths and an 83.3% reduction in length of final stay occurred when 50% of acute care beds were closed, which was followed by an increase when beds began reopening--in terms of both the number of in-patient deaths (4.8%) and the average length of stay (2.6%). The ratio of men to women, the average age of dying in-patients, and the intensity of hospital care changed relatively little over those five years. Most in-patients were admitted for nursing care; in 51.3% of all cases, no diagnostic or therapeutic procedures were performed prior to death. These findings indicate hospital bed availability influences admission to hospital and length of stay, but not treatment decisions affecting seriously ill and dying patients. In addition, reduced length of stay appears to have been a widespread response to hospital downsizing, with this change substantially preserving individual access to hospitals.

  7. Is it recorded in the notes? Documentation of end-of-life care and preferred place to die discussions in the final weeks of life

    PubMed Central

    2011-01-01

    Background Over the past ten years there has been an increasing focus on the need for improving the experience of end of life care. A number of policy initiatives have been introduced to develop approaches to discussing and documenting individual preferences for end of life care, in particular preferred place to die. Methods The aim was to investigate practice in relation to discussing and documenting end of life care and preferred place to die in the last 4 weeks of life with patients and their families. The study utilised an audit of 65 case notes, alongside four group interviews with a mix of health care professionals involved in palliative care provision. Results While there was evidence that discussions relating to end of life care and preferred place to die had taken place in around half of the audited case notes, there appeared to be a lack of a systematic approach to the recording of discussions with patients or carers about these kind of issues. Health care staff subsequently highlighted that initiating discussions about end of life care and preferences in relation to place of death was challenging and that the recording and tracking of such preferences was problematic. Conclusions Further work is required to establish how information may be adequately recorded, revised and transferred across services to ensure that patients' preferences in relation to end of life care and place of death are, as far as possible, achieved. PMID:22053810

  8. A qualitative analysis of the neutron population in fresh and spent fuel assemblies during simulated interrogation using the differential die-away technique

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Tobin, Stephen J.; Lundkvist, Niklas; Goodsell, Alison V.

    In this study, Monte Carlo simulations were performed for the differential die-away (DDA) technique to analyse the time-dependent behaviour of the neutron population in fresh and spent nuclear fuel assemblies as part of the Next Generation Safeguards Initiative Spent Fuel (NGSI-SF) Project. Simulations were performed to investigate both a possibly portable as well as a permanent DDA instrument. Taking advantage of a custom made modification to the MCNPX code, the variation in the neutron population, simultaneously in time and space, was examined. The motivation for this research was to improve the design of the DDA instrument, as it is bemore » ing considered for possible deployment at the Central Storage of Spent Nuclear Fuel and Encapsulation Plant in Sweden (Clab), as well as to assist in the interpretation of the both simulated and measured signals.« less

  9. A Numerical Study on the Streams of Star Debris after Tidal Disruption

    NASA Astrophysics Data System (ADS)

    Camacho Olachea, Priscila; Ramirez-Ruiz, Enrico; Law-Smith, Jamie

    2017-01-01

    Lurking at the centers of most galaxies are gigantic star and gas devouring monsters. These monsters are supermassive black holes (SMBHs), some of which are larger than our solar system and ten billion times as massive as our own Sun. The vast majority of stars in the universe live for tens of billions of years, eventually dying from old age as the nuclearreactions that power them become progressively less effective. But for every ten thousand stars that die peacefully, one star will be brutally torn apart by the extreme tidal forces present as it passes near a SMBH. My recent work has been to develop computational tools necessary to study the fates of stars disrupted by SMBHs. In this research project I presentthe results of my numerical study aimed at understanding the streams of star debris that result after disruption.

  10. ResQFoam for the Treatment of Non-Compressible Hemorrhage on the Front Line.

    PubMed

    Chang, Julius C; Holloway, Brian C; Zamisch, Monica; Hepburn, Matthew J; Ling, Geoffrey S F

    2015-09-01

    Noncompressible torso hemorrhage is the leading cause of potentially survivable death on the battlefield. While medical advances have decreased the rate of "died of wounds" to less than 5%, significant treatment limitations in pre-hospital care remain. To address this persistent capability gap, the Defense Advanced Research Projects Agency launched the Wound Stasis System program in 2010. Under that program, Arsenal Medical, in collaboration with Massachusetts General Hospital and Harvard Medical School, developed a novel, self-expanding polyurethane foam that rapidly treats major abdominal bleeding due to trauma, for use at the point of care. This foam treatment is envisioned as an emergency "bridge to surgery" for warfighters who would otherwise die in the field. This commentary presents this emerging technology with the objective to bring to the community's attention a potentially promising device for the treatment of noncompressible abdominal hemorrhage. Reprint & Copyright © 2015 Association of Military Surgeons of the U.S.

  11. A qualitative analysis of the neutron population in fresh and spent fuel assemblies during simulated interrogation using the differential die-away technique

    DOE PAGES

    Tobin, Stephen J.; Lundkvist, Niklas; Goodsell, Alison V.; ...

    2015-12-01

    In this study, Monte Carlo simulations were performed for the differential die-away (DDA) technique to analyse the time-dependent behaviour of the neutron population in fresh and spent nuclear fuel assemblies as part of the Next Generation Safeguards Initiative Spent Fuel (NGSI-SF) Project. Simulations were performed to investigate both a possibly portable as well as a permanent DDA instrument. Taking advantage of a custom made modification to the MCNPX code, the variation in the neutron population, simultaneously in time and space, was examined. The motivation for this research was to improve the design of the DDA instrument, as it is bemore » ing considered for possible deployment at the Central Storage of Spent Nuclear Fuel and Encapsulation Plant in Sweden (Clab), as well as to assist in the interpretation of the both simulated and measured signals.« less

  12. Identifying care actions to conserve dignity in end-of-life care.

    PubMed

    Brown, Hilary; Johnston, Bridget; Ostlund, Ulrika

    2011-05-01

    Community nurses have a central role in the provision of palliative and end-of-life care; helping people to die with dignity is an important component of this care. To conserve dignity, care should comprise a broad range of actions addressing the distress that might impact on the patient's sense of dignity. These care actions need to be defined. This study aims to suggest care actions that conserve dignity at the end of life based on evidence from local experience and community nursing practice. Data were collected by focus group interviews and analysed by framework analysis using the Chochinov model of dignity as a predefined framework. Suggestions on care actions were given in relation to all themes. As part of a multi-phase project developing and testing a dignity care pathway, this study might help community nurses to conserve dying patients' dignity.

  13. Computer Aided Drafting Curriculum for Vocational Drafting. A Competency Based Unit of Instruction. Final Report.

    ERIC Educational Resources Information Center

    Peck, Greg

    This document contains (1) the final report of a project to develop a computer-aided drafting (CAD) curriculum and (2) a competency-based unit of instruction for use with the CADAPPLE system. The final report states the problem and project objective, presents conclusions and recommendations, and includes survey instruments. The unit is designed…

  14. Blood culture positive Nocardia asteroides infection: a case report.

    PubMed

    Höpler, Wolfgang; Laferl, Hermann; Szell, Marton; Pongratz, Peter; Brandl, Irmgard; Tucek, Gerhard; Wenisch, Christoph

    2013-01-01

    We report a case of nocardiosis in a patient with several risk factors for this rare infection. Radiologically, the patient's multiple lung abscesses were misinterpreted as pulmonary metastases. Diagnosis was finally reached by the growth of Nocardia asteroides in two different blood culture sets. Nocardia bacteraemia is a rare clinical event. Despite initiation of an effective antibiotic therapy, the patient died. Autopsy revealed disseminated nocardial abscesses in the lungs, the kidneys and the brain.

  15. Fatal invasive trichosporonosis due to Trichosporon loubieri in a patient with T-lymphoblastic lymphoma.

    PubMed

    Gabriel, F; Noel, T; Accoceberry, I

    2011-04-01

    This study describes the third known human case of an invasive infection caused by Trichosporon loubieri. The 21-year-old patient was suffering from a third relapse of T-lymphoblastic lymphoma and had been in pancytopenia for three months when she developed a blood trichosporonosis. The patient died 10 days later, despite intravenous voriconazole therapy. Final unequivocal identification of the strain was done using molecular biology tools.

  16. Fiscal Year (FY) 2017 Activities for the Spent Fuel Nondestructive Assay Project

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Trellue, Holly Renee; Trahan, Alexis Chanel; McMath, Garrett Earl

    The main focus of research in the NA-241 spent fuel nondestructive assay (NDA) project in FY17 has been completing the fabrication and testing of two prototype instruments for upcoming spent fuel measurements at the Clab interim storage facility in Sweden. One is a passive instrument: Differential Die-away Self Interrogation-Passive Neutron Albedo Reactivity (DDSI), and one is an active instrument: Differential Die-Away-Californium Interrogation with Prompt Neutron (DDA). DDSI was fabricated and tested with fresh fuel at Los Alamos National Laboratory in FY15 and FY16, then shipped to Sweden at the beginning of FY17. Research was performed in FY17 to simplify resultsmore » from the data acquisition system, which is complex because signals from 56 different 3He detectors must be processed using list mode data. The DDA instrument was fabricated at the end of FY16. New high count rate electronics better suited for a spent fuel environment (i.e., KM-200 preamplifiers) were built specifically for this instrument in FY17, and new Tygon tubing to house electrical cables was purchased and installed. Fresh fuel tests using the DDA instrument with numerous configurations of fuel rods containing depleted uranium (DU), low enriched uranium (LEU), and LEU with burnable poisons (Gd) were successfully performed and compared to simulations.1 Additionally, members of the spent fuel NDA project team travelled to Sweden for a “spent fuel characterization and decay heat” workshop involving simulations of spent fuel and analysis of uncertainties in decay heat calculations.« less

  17. A Process Evaluation of Project Developmental Continuity: Final Report of the PDC Feasibility Study, 1974-1977.

    ERIC Educational Resources Information Center

    Love, John M.; And Others

    This is the final report of the 3-year feasibility phase of a projected 7-year longitudinal evaluation of Project Developmental Continuity (PDC), a Head Start demonstration program aimed at providing educational and developmental continuity between children's Head Start and primary school experiences. Chapter I gives an overview of the PDC program…

  18. Project Continuity: A Handicapped Children's Early Education Project. Final Report, October 1, 1986 to September 30, 1989.

    ERIC Educational Resources Information Center

    Jackson, Barbara; Quinn, Judy

    The final report describes Project Continuity, a federally funded effort to provide continuity of care for handicapped infants with chronic illness or complex medical needs while in the acute care setting and to facilitate transition of the infant into the home environment. Goals were accomplished within the context of a family-centered…

  19. 75 FR 57286 - Notice of Availability of the Final Environmental Impact Statement for the NextLight Renewable...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-20

    ... Statement for the NextLight Renewable Power, LLC, Silver State Solar Project, Clark County, NV AGENCY... Statement (EIS) for the Silver State Solar Project, Clark County, Nevada, and by this notice is announcing its availability. DATES: The BLM will not issue a final decision on the Silver State Solar Project for...

  20. Professional Development Capacity Building in Pennsylvania's Regional Staff Development Program: The "WorkNet" Project. Final Report [and] WorkNet Workplace Literacy Trainer's Guide.

    ERIC Educational Resources Information Center

    Carman, Priscilla S.

    These two documents are products of a project to improve the capability of the Pennsylvania Regional Staff Development Centers to provide current, research-based workplace literacy training and technical assistance to adult basic and literacy education programs. The final report describes these project activities: development of training materials…

  1. Broward County Library, Final Performance Report for Library Services and Construction Act (LSCA) Title VI, Library Literacy Program.

    ERIC Educational Resources Information Center

    Hansen, Janet

    This final performance report for the Broward County Library New Reader Services Coordinator literacy project begins with a section that provides quantitative data. The next section compares actual accomplishments to the project objectives for 1992-93, including the hiring of a new reader as coordinator for the project and the establishment of…

  2. Technical Assistance in Evaluating Career Education Projects. Final Report. Volume II: Final Career Education Evaluation Report.

    ERIC Educational Resources Information Center

    Stenner, A. Jackson; And Others

    This document contains the second of five volumes reporting the activities and results of a career education evaluation project conducted to accomplish the following two objectives: (1) to improve the quality of evaluations by career education projects funded by the United States Office of Career Education (OCE) through the provision of technical…

  3. Harmony in Career Learning and Scholastic System (Project HI-CLASS). Final Evaluation Report 1992-93. OREA Report.

    ERIC Educational Resources Information Center

    Duque, Diana L.

    Harmony in Career Learning and Scholastic System (Project HI-CLASS) was a Transitional Bilingual Education Title VII-funded program in its fifth and final year in 1992-93. The project offered instructional and support services to 641 students of limited English proficiency (LEP) at three sites, all of which had many immigrant students, in…

  4. Studies in Bilingual Evaluation, Work Unit I: Bilingual Prediction Project. Final Report.

    ERIC Educational Resources Information Center

    de Porcel, Antonio; And Others

    The final report of the Bilingual Prediction Project presents a review of the project from its inception in 1975 through completion in 1979. The main goal was to predict a student's academic ability in English. A prediction index was constructed in two stages. The first stage was a description of the target population and their school setting, as…

  5. Conflict Management in Schools: Sowing Seeds for a Safer Society. Final Report of the School Conflict Management Demonstration Project 1990-1993.

    ERIC Educational Resources Information Center

    Wheeler, Terrence; And Others

    In August 1990, the Ohio Commission on Dispute Resolution and Conflict Management initiated a three-year School Conflict Management Demonstration Project. This publication is the final report on the Project. Twenty schools, which reflected the state's diversity, were selected to help assess the impact of the conflict management programs. The…

  6. The CDCC's Project No. 7: "The Education and Cultural Development of Migrants." Final Report of the Project Group.

    ERIC Educational Resources Information Center

    Council for Cultural Cooperation, Strasbourg (France).

    The final report of a project group representing the 18 member countries of the Council of Europe Council for Cultural Co-operation investigates education and cultural development of migrants. The report discusses methodology and reasons for selecting an intercultural approach to migrant education in terms of interculturalism's basic elements:…

  7. "Perhaps I will die young." Fears and worries regarding disease and death among Danish adolescents and young adults with cancer. A mixed method study.

    PubMed

    Hølge-Hazelton, Bibi; Timm, Helle U; Graugaard, Christian; Boisen, Kirsten A; Sperling, Cecilie Dyg

    2016-11-01

    A cross-sectional national study was initiated in order to evaluate healthcare services and survivorship from the perspective of Danish adolescents and young adults (AYAs) with cancer. The purpose of the paper was to examine (Q1) to what extend Danish AYAs experienced fears and worries about dying; (Q2) with whom, if anyone, they had shared those worries; and finally, (Q3) how fears and worries influenced their daily life. The emphasis will be on Q3. A 151-item questionnaire (including two closed- and one open-ended questions about fears of death and dying) was distributed among all 15-29-year-old Danes registered with a cancer diagnosis from 2009 to 2013. A total study population of 822 persons participated. Data was analyzed using a mixed design of descriptive statistics and qualitative content analysis. Q1: Almost 80 % of AYAs with cancer expressed some worries about death; hereof, more than half of them expressed quite a bit or very much. The analysis showed significant gender differences, whereas age and duration of disease did not have any significant impact on such thoughts. Q2: One third had not talked to anybody about his or her worries. Q3: The analysis resulted in three overall categories: fear of disease and death having little or no influence (n = 100), fear influencing in various ways (n = 215), and fear of disease and death having a substantial influence (n = 75). The majority of AYAs had experienced fears and worries about dying, but one third of them had not talked to anybody about those thoughts. It is an important clinical point that young age does not preclude fears and worries about dying in AYAs with cancer.

  8. Design of Channel Type Indirect Blank Holder for Prevention of Wrinkling and Fracture in Hot Stamping Process

    NASA Astrophysics Data System (ADS)

    Choi, Hong-seok; Ha, Se-yoon; Cha, Seung-hoon; kang, Chung-gil; Kim, Byung-min

    2011-08-01

    The hot stamping process has been used in the automotive industry to reduce the weight of the body-in-white and to increase passenger safety via improved crashworthiness. In this study, a new form die with a simple structure that can prevent defects such as wrinkle and fracture is proposed for the manufacture of hot stamped components. The wrinkling at the flange cannot be eliminated when using a conventional form die. It is known that the initiation of wrinkling is influenced by many factors such as the mechanical properties of the sheet material, geometry of the sheet and tool, and other process parameters, including the blank holding force (BHF) and the contact conditions. In this research, channel type indirect blank holder (CIBH) is introduced to replace general blank holder for manufacturing the hot stamped center pillar. First, we investigate the tension force acting on the blank according to the channel shapes. We determine the appropriate range by comparing the tension force with the upper and lower BHFs in a conventional stamping process. We then use FE-analysis to study the influence of the slope angle and corner radius of the channel on the formability. Finally, the center pillar is manufactured using the form die with the selected channel.

  9. Effects of sintering time and temperature to the characteristics of FeCrAl powder compacts formed at elevated temperature

    NASA Astrophysics Data System (ADS)

    Rahman, M. M.; Rahman, H. Y.; Awang, M. A. A.; Sopyan, I.

    2018-01-01

    This paper presents the outcomes of an experimental investigation on the effect of sintering schedule, i.e., holding time and temperature to the final properties of FeCrAl powder compacts prepared through uniaxial die compaction process at above room temperature. The feedstock was prepared by mechanically mixing iron powder ASC 100.29 with chromium (22 wt%) and aluminium (11 wt%) for 30 min at room temperature. A cylindrical shape die was filled with the powder mass and heated for one hour for uniform heating of the die assembly together with the powder mass. Once the temperature reached to the setup temperature, i.e., 150°C, the powder mass was formed by applying an axial pressure of 425 MPa simultaneously from upward and downward directions. The as-pressed green compacts were then cooled to room temperature and subsequently sintered in argon gas fired furnace at a rate of 5°C/min for three different holding times, i.e., 30, 60, and 90 min at three different sintering temperatures, i.e., 800, 900, and 1000°C. The sintered samples were characterized for their density, electrical resistivity, bending strength, and microstructure. The results revealed that the sample sintered at 1000°C for 90 min achieved the better characteristics.

  10. Describing the social environment of elderly persons at the time of death.

    PubMed

    Werner, Perla; Miron, Ehud; Beeri, Michal Schnaider; Davidson, Michael; Noy, Shlomo

    2005-04-01

    To describe the social environment of elderly persons at the time of their death and its correlates. Telephone interviews with the next-of-kin of deceased elderly persons. Potential participants were the next-of-kin of all Jewish elderly individuals who died during the course of one year in a major city in the northern part of Israel. The final sample included 139 participants (58% response rate; 70% cooperation rate). Information was collected regarding the decedents' social environment three days before their death and at the time of death. Eight types of informal sources of support and four sources of formal support were examined. The correlates examined included the decedents' demographic, health, social, and death characteristics. The majority of the decedents died while surrounded by at least one family member. Having a larger social network was associated with a larger number of persons present at the time of death. Being informed about the impending death was associated with a larger number of persons from the formal and informal networks present at the time of death. The common fear of dying alone and isolated was not confirmed by this study. Increased efforts should be invested in helping professionals to deal with the difficulties inherent to the process of diagnosing an upcoming death.

  11. Caring for the dying patient in the ICU--the past, the present and the future.

    PubMed

    Fridh, Isabell

    2014-12-01

    The aim of this paper is to present the state of the science concerning issues in end-of-life (EOL) care which have an impact on intensive care nurses possibilities to provide nursing care for dying patients and their families. The perspective of families is also illuminated and finally ethical challenges in the present and for the future are discussed. The literature review revealed that the problem areas nurses report concerning EOL care have been the same over three decades. Most problems are related to inter-disciplinary collaboration and communication with the medical profession about the transition from cure to comfort care. Nurses need enhanced communication skills in their role as the patient's advocate. Education in EOL care and a supportive environment are prerequisites for providing EOL care. Losing a loved one in the ICU is a stressful experience for close relatives and nursing care has a profound impact on families' memories of the EOL care given to their loved ones. It is therefore important that ICU nurses are aware of families' needs when a loved one is dying and that follow-up services are appreciated by bereaved family members. Ethical challenges are related to changed sedation practices, organ donation, globalisation and cultural sensitivity. Copyright © 2014 Elsevier Ltd. All rights reserved.

  12. 78 FR 11267 - Notice of Final Federal Agency Actions on Proposed Highway in California

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-15

    ... the Final Environmental Assessment (FEA) for the project, approved on 2/8/13, in the FHWA Finding of.... The FEA, FONSI, and other project records are available by contacting Caltrans at the addresses...

  13. 78 FR 23631 - Notice of Final Federal Agency Actions on Proposed Highway in California

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-19

    ... in the Final Environmental Assessment (FEA) for the project, approved on 12/19/12, in the FHWA... records. The FEA, FONSI, and other project records are available by contacting Caltrans at the addresses...

  14. 76 FR 16653 - Notice of Final Federal Agency Actions on Proposed Highway in California

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-24

    ... described in the Final Environmental Assessment (FEA) for the project, approved via issuance of a Finding of... records. The FEA, FONSI, and other project records are available by contacting Caltrans at the addresses...

  15. Snow removal performance metrics : final report.

    DOT National Transportation Integrated Search

    2017-05-01

    This document is the final report for the Clear Roads project entitled Snow Removal Performance Metrics. The project team was led by researchers at Washington State University on behalf of Clear Roads, an ongoing pooled fund research effort focused o...

  16. Final report on the maintenance asset management project : phase II.

    DOT National Transportation Integrated Search

    2013-07-01

    Iowa Department of Transportation (IA DOT) is finalizing research to streamline field inventory/inspection of culverts by Maintenance and Construction staff while maximizing the use of tablet technologies. The project began in 2011 to develop some ne...

  17. Mapping evaporative water loss in desert passerines reveals an expanding threat of lethal dehydration.

    PubMed

    Albright, Thomas P; Mutiibwa, Denis; Gerson, Alexander R; Smith, Eric Krabbe; Talbot, William A; O'Neill, Jacqueline J; McKechnie, Andrew E; Wolf, Blair O

    2017-02-28

    Extreme high environmental temperatures produce a variety of consequences for wildlife, including mass die-offs. Heat waves are increasing in frequency, intensity, and extent, and are projected to increase further under climate change. However, the spatial and temporal dynamics of die-off risk are poorly understood. Here, we examine the effects of heat waves on evaporative water loss (EWL) and survival in five desert passerine birds across the southwestern United States using a combination of physiological data, mechanistically informed models, and hourly geospatial temperature data. We ask how rates of EWL vary with temperature across species; how frequently, over what areas, and how rapidly lethal dehydration occurs; how EWL and die-off risk vary with body mass; and how die-off risk is affected by climate warming. We find that smaller-bodied passerines are subject to higher rates of mass-specific EWL than larger-bodied counterparts and thus encounter potentially lethal conditions much more frequently, over shorter daily intervals, and over larger geographic areas. Warming by 4 °C greatly expands the extent, frequency, and intensity of dehydration risk, and introduces new threats for larger passerine birds, particularly those with limited geographic ranges. Our models reveal that increasing air temperatures and heat wave occurrence will potentially have important impacts on the water balance, daily activity, and geographic distribution of arid-zone birds. Impacts may be exacerbated by chronic effects and interactions with other environmental changes. This work underscores the importance of acute risks of high temperatures, particularly for small-bodied species, and suggests conservation of thermal refugia and water sources.

  18. Mapping evaporative water loss in desert passerines reveals an expanding threat of lethal dehydration

    PubMed Central

    Mutiibwa, Denis; Gerson, Alexander. R.; Smith, Eric Krabbe; Talbot, William A.; O’Neill, Jacqueline J.; McKechnie, Andrew E.; Wolf, Blair O.

    2017-01-01

    Extreme high environmental temperatures produce a variety of consequences for wildlife, including mass die-offs. Heat waves are increasing in frequency, intensity, and extent, and are projected to increase further under climate change. However, the spatial and temporal dynamics of die-off risk are poorly understood. Here, we examine the effects of heat waves on evaporative water loss (EWL) and survival in five desert passerine birds across the southwestern United States using a combination of physiological data, mechanistically informed models, and hourly geospatial temperature data. We ask how rates of EWL vary with temperature across species; how frequently, over what areas, and how rapidly lethal dehydration occurs; how EWL and die-off risk vary with body mass; and how die-off risk is affected by climate warming. We find that smaller-bodied passerines are subject to higher rates of mass-specific EWL than larger-bodied counterparts and thus encounter potentially lethal conditions much more frequently, over shorter daily intervals, and over larger geographic areas. Warming by 4 °C greatly expands the extent, frequency, and intensity of dehydration risk, and introduces new threats for larger passerine birds, particularly those with limited geographic ranges. Our models reveal that increasing air temperatures and heat wave occurrence will potentially have important impacts on the water balance, daily activity, and geographic distribution of arid-zone birds. Impacts may be exacerbated by chronic effects and interactions with other environmental changes. This work underscores the importance of acute risks of high temperatures, particularly for small-bodied species, and suggests conservation of thermal refugia and water sources. PMID:28193891

  19. Farewell to Diversity? New State Zones of Health Care Service in China’s Far West

    PubMed Central

    Klotzbücher, Sascha; Lässig, Peter; Jiangmei, Qin; Dongsheng, Rui; Weigelin-Schwiedrzik, Susanne

    2014-01-01

    Using James Scott’s (2009) theoretical framework of the interaction between the state and peripheral people, we argue that the welfare state should be regarded as a pull-factor in the context of the state’s endeavours to project its power to distant peoples in assigned state zones. Our discussion is based on interviews in Xinyuan County in the Western part of the Xinjiang Uyghur Autonomous Region, China. Presenting current policies and alternative policy options discussed at the local level for providing primary health care in rural China, we argue that decisions made in the implementation process did not respond to the special health needs of mobile pastoralists in the high plains, but were part of the central state logic of homogenising settlement efforts and health care. Der theoretische Ansatz von James Scott zu Expansion von staatlicher Ordnung auf periphere Randgebiete wird auf den Aufbau von Wohlfahrts- und Gesundheitspolitik des modernen Staates angewendet und weiterentwickelt. Anhand mehrjähriger Feldstudien zwischen 2005 und 2009 zur Gesundheitsversorgungsstruktur im Kreis Xinyuan der Autonomen Uighurischen Region Xinjiang in der Volksrepublik China werden zuerst die nationalen Restrukturierungsmaßnahmen vorgestellt und Lösungen für eine bessere Versorgung der halbnomadisierenden kasachischen Hirtenfamilien diskutiert. Lokal entwickelte und an die nomadischen Lebensformen angepasste mobile Lösungen zur Gesundheitsfürsorge konnten nicht implementiert werden. Die Anstrengungen der staatlichen Akteure sind als Versuch zu sehen, bisher marginalisierte Gruppen aus den peripheren Gebirgsregionen und über die Integration in eine staatliche Gesundheitsversorgung in den Tälern anzusiedeln. PMID:25729121

  20. Updated Global Patterns of Drought and Heat-Induced Forest Die-off, and Ecohydrological Feedbacks

    NASA Astrophysics Data System (ADS)

    Allen, C. D.

    2011-12-01

    Ongoing climate changes - particularly increases in mean temperatures as well as frequencies, durations, and severities of extreme drought and heat - can amplify tree physiological stress and thereby drive increases in both background tree mortality rates and episodes of rapid, broad-scale forest die-off. Updates are presented to a recent global synthesis of documented tree mortality episodes attributed to drought and/or heat, further expanding the documented spatial distribution and demonstrating the vulnerability of all major forest types from tropical moist forests and savannas to temperate and boreal forests. Given that anthropogenic climate change is projected to drive substantial increases in both mean temperatures and the frequency/duration/severity of extreme drought and heat in many regions, recent episodes of broad-scale drought-induced forest mortality may reflect increasing global risks of forest die-off, even in environments not normally considered water-limited. Since vegetation cover patterns are closely and interactively linked with ecosystem water fluxes, episodes of massive forest die-off can be expected to significantly affect ecohydrological patterns and processes, ranging from runoff and erosion to evaporation and transpiration, often with nonlinear threshold responses expected. Diverse examples of such feedbacks between climate-induced forest mortality and ecohydrology are presented, ranging from detailed observations of linked changes in vegetation, runoff, and erosion in response to forest mortality in the southwestern US to Western Australia and Amazonian rainforest water cycling. Current research efforts to address the large knowledge gaps that at present hinder our ability to predict climate-induced forest mortality and associated ecohydrological responses are discussed.

  1. The final size of a SARS epidemic model without quarantine

    NASA Astrophysics Data System (ADS)

    Hsu, Sze-Bi; Roeger, Lih-Ing W.

    2007-09-01

    In this article, we present the continuing work on a SARS model without quarantine by Hsu and Hsieh [Sze-Bi Hsu, Ying-Hen Hsieh, Modeling intervention measures and severity-dependent public response during severe acute respiratory syndrome outbreak, SIAM J. Appl. Math. 66 (2006) 627-647]. An "acting basic reproductive number" [psi] is used to predict the final size of the susceptible population. We find the relation among the final susceptible population size S[infinity], the initial susceptible population S0, and [psi]. If [psi]>1, the disease will prevail and the final size of the susceptible, S[infinity], becomes zero; therefore, everyone in the population will be infected eventually. If [psi]<1, the disease dies out, and then S[infinity]>0 which means part of the population will never be infected. Also, when S[infinity]>0, S[infinity] is increasing with respect to the initial susceptible population S0, and decreasing with respect to the acting basic reproductive number [psi].

  2. Development of a Thin-Wall Magnesium side door Inner Panel for Automobiles

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Jekl, J.; Auld, J.; Sweet, C.

    Cast magnesium side door inner panels can provide a good combination of weight, functional, manufacturing and economical requirements. However, several challenges exist including casting technology for thin-wall part design, multi-material incompatibility and relatively low strength vs steel. A project has been initiated, supported by the US Department of Energy, to design and develop a lightweight frame-under-glass door having a thin-wall, full die-cast, magnesium inner panel. This development project is the first of its kind within North America. Phase I of the project is now complete and the 2.0mm magnesium design, through casting process enablers, has met or exceeded all stiffnessmore » requirements, with significant mass reduction and part consolidation. In addition, a corrosion mitigation strategy has been established using industry-accepted galvanic isolation methods and coating technologies.« less

  3. Final Technical Report: Intensive Quenching Technology for Heat Treating and Forging Industries

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Aronov, Michael A.

    2005-12-21

    Intensive quenching (IQ) process is an alternative way of hardening (quenching) steel parts through the use of highly agitated water and then still air. It was developed by IQ Technologies, Inc. (IQT) of Akron, Ohio. While conventional quenching is usually performed in environmentally unfriendly oil or water/polymer solutions, the IQ process uses highly agitated environmentally friendly water or low concentration water/mineral salt solutions. The IQ method is characterized by extremely high cooling rates of steel parts. In contrast to conventional quenching, where parts cool down to the quenchant temperature and usually have tensile or neutral residual surface stresses at themore » end of quenching. The IQ process is interrupted when the part core is still hot and when there are maximum compressive stresses deep into the parts, thereby providing hard, ductile, better wear resistant parts. The project goal was to advance the patented IQ process from feasibility to commercialization in the heat-treating and forging industries to reduce significantly energy consumption and environmental impact, to increase productivity and to enhance economic competitiveness of these industries as well as Steel, Metal Casting and Mining industries. To introduce successfully the IQ technology in the U.S. metal working industry, the project team has completed the following work over the course of this project: A total of 33 manufacturers of steel products provided steel parts for IQ trails. IQT conducted IQ demonstrations for 34 different steel parts. Our customers tested intensively quenched parts in actual field conditions to evaluate the product service life and performance improvement. The data obtained from the field showed the following: Service life (number of holes punched) of cold-work punches (provided by EHT customer and made of S5 shock-resisting steel) was improved by two to eight times. Aluminum extrusion dies provided by GAM and made of hot work H-13 steel outperformed the standard dies by at least 50%. Dies provided by an AST customer, made of plain carbon 1045 steel and used for pellet manufacturing outperformed the standard dies by more than 100%. Concrete crusher liner wear plates provided by an EHT customer and made of 1045 steel, had the same surface hardness as the plates made of more expensive, pre-hardened high alloy HARDOX-500 material supplied by a Swedish company and used currently by the EHT customer. The 1045 material intensively quenched wear plates are currently in the field. Concrete block molding machine wear plates provided by an IQT customer and made of 8620 steel were processed at the AST production IQ system using a 40% reduced carburization cycle. An effective case depth in the intensively quenched wear plates was the same as in the standard, oil quenched parts. Base keys provided by an EHT customer and made of 8620 steel were processed using a 40% reduced carburization cycle. The intensively quenched parts showed the same performance as standard parts. IQT introduced the IQ process in heat treat practices of three commercial heat-treating shops: Akron Steel Treating Co., Summit Heat Treating Co. and Euclid Heat Treating Co. CWRU conducted a material characterization study for a variety of steels to develop a database to support changing/modification of recognized standards for quenching steel parts. IQT conducted a series of IQ workshops, published seven technical papers and participated in ASM Heat Treating Society conference and exposition and in Furnace North America Show. IQT designed and built a fully automated new IQ system installed at the Center for Intensive Quenching. This system includes the following major components: a stand-alone 1,900-gallon IQ water system, a 24'' x 24'' atmosphere pit furnace, and an automated load transfer mechanism. IQT established a ''Center for Intensive Quenching'' at the AST facilities. The 4,000 square feet Center includes the following equipment: High-velocity single part quenching IQ unit developed and built previously under EMTEC CT-65 project. The unit is equipped with a neutral salt bath furnace and a high-temperature, electric-fired, atmosphere, box furnace. New 1,900 gallon IQ system with a 24'' x 24'' atmosphere pit furnace and a load transfer mechanism. Shaker hearth furnace equipped with an IQ water tank and with a chiller to maintain the required water temperature. Potential Savings for USA Heat Treating Industry IQ Process Benefit/Annual Benefit for USA Heat Treating Industry Full elimination or 30% reduction of the carburization cycle Savings of 1,800 billion Btu of energy Cost reduction by $600,000,000 Reduction of CO2 emissions by 148,000 ton Part weight reduction by 5% Savings in material cost of $70,000,000 Savings of 300 billion Btu of energy« less

  4. Water Resources Research Grant Program Project Descriptions: Fiscal Year 1988

    USGS Publications Warehouse

    Lew, Melvin; McCoy, Beverly M.

    1989-01-01

    This report contains information on the 38 new projects funded by the U.S. Geological Survey's Water Resources Research Grant Program in fiscal year 1988 and on 11 projects completed during the year. For the new projects, the report gives the grant number, project title, performing organization, principal investigator(s), project duration, and a project description that includes: (1) identification of water-related problems and problem-solution approach, (2) contribution to problem solution, (3) objectives, and (4) approach. The 38 projects include 14 in the area of ground-water quality problems, 10 in the science and technology of water-quality management, 4 in climate variability and the hydrologic cycle, 7 in institutional change in water-resources management, and 3 in miscellaneous water-resources management problems. For the 11 completed projects, the report gives the grant number, project title, performing organization, principal investigator(s), starting date, date of receipt of final report, and an abstract of the final report. Each project description provides the information needed to obtain a copy of the final report. The report also contains tables showing (1) proposals received according to area of research interest, (2) grant awards and funding according to area of research interest, (3) proposals received according to type of submitting organization, and (4) awards and funding according to type of organization.

  5. Telephone Flat Geothermal Development Project Environmental Impact Statement Environmental Impact Report. Final: Comments and Responses to Comments

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    None

    This document is the Comments and Responses to Comments volume of the Final Environmental Impact Statement and Environmental Impact Report prepared for the proposed Telephone Flat Geothermal Development Project (Final EIS/EIR). This volume of the Final EIS/EIR provides copies of the written comments received on the Draft EIS/EIR and the leady agency responses to those comments in conformance with the requirements of the National Environmental Policy Act (NEPA) and the California Environmental Quality Act (CEQA).

  6. Iowa Hill Pumped Storage Project Investigations - Final Technical Report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hanson, David

    2016-07-01

    This Final Technical Report is a summary of the activities and outcome of the Department of Energy (DOE) Assistance Agreement DE-EE0005414 with the Sacramento Municipal Utility District (SMUD). The Assistance Agreement was created in 2012 to support investigations into the Iowa Hill Pumped-storage Project (Project), a new development that would add an additional 400 MW of capacity to SMUD’s existing 688MW Upper American River Hydroelectric Project (UARP) in the Sierra Nevada mountains east of Sacramento, California.

  7. 76 FR 62495 - Notice of Final Federal Agency Actions on a Local Arterial in California

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-07

    ... described in the Final Environmental Assessment (FEA) and Finding of No Significant Impact (FONSI) for the project, both approved on September 1, 2011, and in other documents in Caltrans' project records. The FEA...

  8. Palmdale Energy Project; Final Decision; Prevention of Significant Deterioration (PSD) Permit

    EPA Pesticide Factsheets

    EPA Region 9 is issuing a final decision to grant conditional approval, in accordance with the Clean Air Act, for the construction of a natural gas-fired combined cycle power plant known as the Palmdale Energy Project.

  9. 35. From Final Construction Report on the Haleakala Road ProjectNR7, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    35. From Final Construction Report on the Haleakala Road Project--NR-7, Hawaii National Park, Island of Maui, Territory of Hawaii. LOOKING BACK FROM STATION 335 AT RETURN CURVE. - Haleakala National Park Roads, Pukalani, Maui County, HI

  10. 36. From Final Construction Report on the Haleakala Road ProjectNR7, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    36. From Final Construction Report on the Haleakala Road Project--NR-7, Hawaii National Park, Island of Maui, Territory of Hawaii. TYPICAL RUBBLE MASONRY HEADWALL AND BOX CULVERT. - Haleakala National Park Roads, Pukalani, Maui County, HI

  11. Vocational Evaluation and Work Adjustment Bulletin; Vol. 8, Special Edition: Vocational Evaluation Project Final Report Part 2.

    ERIC Educational Resources Information Center

    Vocational Evaluation and Work Adjustment Association, Washington, DC.

    Part 2 of the three-part Vocational Evaluation Project final report contains brief summaries of the seven task force report which comprise the final report and two such task force reports. The report of task force 5, Standards for Vocational Evaluation, describes the task force's effort to study the standards for accreditation presently used by…

  12. JPL-20170825-CASSINf-0001-Cassini Nears the End of Its Mission Video File

    NASA Image and Video Library

    2017-08-25

    On Sept. 15, 2017, NASA's Cassini spacecraft will end it mission by diving into the atomosphere of Saturn. Animation: one of Cassini's final passes between Saturn and its rings, Cassini's final 22 orbits, final plunge. Footage: construction of Cassini at JPL. Interview excerpts from Linda Spilker, Cassini Project Scientist; Earl Maize, Cassini Project Manager; Julie Webster, Cassini Spacecraft Operations Manager.

  13. Family food practices: relationships, materiality and the everyday at the end of life.

    PubMed

    Ellis, Julie

    2018-02-01

    This article draws on data from a research project that combined participant observation with in-depth interviews to explore family relationships and experiences of everyday life during life-threatening illness. In it I suggest that death has often been theorised in ways that make its 'mundane' practices less discernible. As a means to foreground the everyday, and to demonstrate its importance to the study of dying, this article explores the (re)negotiation of food and eating in families facing the end of life. Three themes that emerged from the study's broader focus on family life are discussed: 'food talk' and making sense of illness; food, family and identity; and food 'fights'. Together the findings illustrate the material, social and symbolic ways in which food acts relationally in the context of dying, extending conceptual work on materiality in death studies in novel directions. The article also contributes new empirical insights to a limited sociological literature on food, families and terminal illness, building on work that theorises the entanglements of materiality, food, bodies and care. The article concludes by highlighting the analytical value of everyday materialities such as food practices for future research on dying as a relational experience. © 2018 The Author. Sociology of Health & Illness published by John Wiley & Sons Ltd on behalf of Foundation for SHIL.

  14. The dynamics of carbon stored in xylem sapwood to drought-induced hydraulic stress in mature trees

    PubMed Central

    Yoshimura, Kenichi; Saiki, Shin-Taro; Yazaki, Kenichi; Ogasa, Mayumi Y.; Shirai, Makoto; Nakano, Takashi; Yoshimura, Jin; Ishida, Atsushi

    2016-01-01

    Climate-induced forest die-off is widespread in multiple biomes, strongly affecting the species composition, function and primary production in forest ecosystems. Hydraulic failure and carbon starvation in xylem sapwood are major hypotheses to explain drought-induced tree mortality. Because it is difficult to obtain enough field observations on drought-induced mortality in adult trees, the current understanding of the physiological mechanisms for tree die-offs is still controversial. However, the simultaneous examination of water and carbon uses throughout dehydration and rehydration processes in adult trees will contribute to clarify the roles of hydraulic failure and carbon starvation in tree wilting. Here we show the processes of the percent loss of hydraulic conductivity (PLC) and the content of nonstructural carbohydrates (NSCs) of distal branches in woody plants with contrasting water use strategy. Starch was converted to soluble sugar during PLC progression under drought, and the hydraulic conductivity recovered following water supply. The conversion of NSCs is strongly associated with PLC variations during dehydration and rehydration processes, indicating that stored carbon contributes to tree survival under drought; further carbon starvation can advance hydraulic failure. We predict that even slow-progressing drought degrades forest ecosystems via carbon starvation, causing more frequent catastrophic forest die-offs than the present projection. PMID:27079677

  15. The dynamics of carbon stored in xylem sapwood to drought-induced hydraulic stress in mature trees

    NASA Astrophysics Data System (ADS)

    Yoshimura, Kenichi; Saiki, Shin-Taro; Yazaki, Kenichi; Ogasa, Mayumi Y.; Shirai, Makoto; Nakano, Takashi; Yoshimura, Jin; Ishida, Atsushi

    2016-04-01

    Climate-induced forest die-off is widespread in multiple biomes, strongly affecting the species composition, function and primary production in forest ecosystems. Hydraulic failure and carbon starvation in xylem sapwood are major hypotheses to explain drought-induced tree mortality. Because it is difficult to obtain enough field observations on drought-induced mortality in adult trees, the current understanding of the physiological mechanisms for tree die-offs is still controversial. However, the simultaneous examination of water and carbon uses throughout dehydration and rehydration processes in adult trees will contribute to clarify the roles of hydraulic failure and carbon starvation in tree wilting. Here we show the processes of the percent loss of hydraulic conductivity (PLC) and the content of nonstructural carbohydrates (NSCs) of distal branches in woody plants with contrasting water use strategy. Starch was converted to soluble sugar during PLC progression under drought, and the hydraulic conductivity recovered following water supply. The conversion of NSCs is strongly associated with PLC variations during dehydration and rehydration processes, indicating that stored carbon contributes to tree survival under drought; further carbon starvation can advance hydraulic failure. We predict that even slow-progressing drought degrades forest ecosystems via carbon starvation, causing more frequent catastrophic forest die-offs than the present projection.

  16. Assisting Newcomers through Employment and Support Services: An Evaluation of the New Americans Centers Demonstration Project in Arkansas and Iowa. Final Report

    ERIC Educational Resources Information Center

    Koralek, Robin; Johnson, Heidi; Ratcliffe, Caroline; Vericker, Tracy

    2010-01-01

    This report presents the final results for the evaluation of the New Americans Centers (NACs) demonstration project in Arkansas and Iowa. It focuses on program operations and plans for program sustainability, while highlighting services provided through the demonstration projects in Arkansas and Iowa. It also documents outcomes for New Iowan…

  17. Access for All: Collaboration for Comprehensive Child Care for Deaf and Hearing Preschoolers and Their Families. Project Access. Final Report.

    ERIC Educational Resources Information Center

    Solit, Gail A.

    This final report presents activities and accomplishments of a three-year outreach project to link programs and agencies serving deaf and hard of hearing children and their families with child care programs in their communities. Each year project staff provided training in establishing integrated early childhood programming and child care for at…

  18. Thai-Alberta Co-Operative Assessment Project Concerning Thirty-Two Rural Secondary Schools in the Third National Economic and Social Plan, Thailand (1972-1976). Final Report.

    ERIC Educational Resources Information Center

    Chareonchai, Ruang; And Others

    This extensive assessment project report focuses on the Rural Secondary Schools (RSS) Project in Thailand. The background, design, rationale and objectives of the assessment are described, as are the eight phases of the study: reconnaissance; proposals; basic planning and pre-testing; data collection; analysis; academic review; final report; and…

  19. DeKalb County Public Library, Final Performance Report for Library Services and Construction Act (LSCA) Title VI, Library Literacy Program.

    ERIC Educational Resources Information Center

    Des Enfants, Sherry

    This DeKalb County Public Library family literacy project final performance report begins with a section that provides quantitative data on the project. The next section compares actual accomplishments to the following project objectives for fiscal year 1993: (1) to update eight existing literacy collections in branch libraries by the addition of…

  20. Expanding the Circle: South Dakota Deaf-Blind Project. Final Report, 10-1-98 through 9-30-99.

    ERIC Educational Resources Information Center

    South Dakota State Dept. of Education and Cultural Affairs, Pierre.

    This final report describes activities and accomplishments of the South Dakota Deaf-Blind Project, a 4-year federally funded project designed to raise awareness of the need for early identification of children who are deaf-blind and reside on Native American reservation lands. To this end, the states of Montana, Minnesota, North Dakota, Nebraska,…

  1. How the Contents of a Bachelor's Degree Final Project of Engineering Evolve towards Innovative Scientific Knowledge: Keys to Success

    ERIC Educational Resources Information Center

    Núñez, Cristina; Guinea, Ana; Callau, Sara; Bengoa, Christophe; Basco, Josep; Gavaldà, Jordi

    2017-01-01

    The Bachelor's Degree Final Project (BDFP) of our school aims to develop a real constructive project, enhance cooperative teamwork and increase productivity of students. We present a real case study, related with engineering and scientific innovation results obtained by BDFP, which has led to an innovative scientific study presented at the 7th…

  2. The Employment Retention and Advancement Project: How Effective Are Different Approaches Aiming to Increase Employment Retention and Advancement? Final Impacts for Twelve Models. Executive Summary

    ERIC Educational Resources Information Center

    Hendra, Richard; Dillman, Keri-Nicole; Hamilton, Gayle; Lundquist, Erika; Martinson, Karin; Wavelet, Melissa

    2010-01-01

    This report summarizes the final impact results for the national Employment Retention and Advancement (ERA) project. This project tested, using a random assignment design, the effectiveness of numerous programs intended to promote steady work and career advancement. All the programs targeted current and former welfare recipients and other low-wage…

  3. Methodology for Recreation Data Acquisition and Evaluation for Ethnic Minority Visitors to Corps of Engineers Projects

    DTIC Science & Technology

    1999-12-01

    this population segment. But Native Americans are twice as likely to die in motor vehicle accidents. Teen births are common among Chapter 2...These include tuberculosis, disability, and teen pregnancy. Households: Married couples make up a smaller share of Native Ameri- can households... teens by elder Native Americans through the use of traditional Indian recreational activities (e.g., powwows) appears to be an essential component of

  4. Manufacturing Methods and Technology Project Summary Reports.

    DTIC Science & Technology

    1980-12-01

    deposition of chrome-copper (Cr- Cu ), dry-film photoresist application, photolithographic masking, spray etching, die bonding, ultrasonic...4) cold roll forging. Of these, the cold roll forging process is the most widely used for the pro- duction of steel and low alloy blades. It provides... sprayed Mo- Al -Ni both provide relatively good wear resistance, see Figure 1. The powder -flame sprayed aluminum bronze did not perform as well. 147 -S t. I

  5. Space Junk Norms: US Advantages in Creating a Debris Reducing Outer Space Norm

    DTIC Science & Technology

    2011-05-01

    and White Knight ,” http://www.scaled.com/projects/tierone/ (accessed 25 March 2011). 26 Mike Moore argues that the nearest global competitor to the...formation of norms. 27 For an explanation of the US 2008 ASAT test, see Jamie McIntyre...the Space Age. Baltimore: Johns Hopkins University Press, 1997. McIntyre, Jamie , Suzanne Malveaux and Miles O’Brien. “Navy Missile Hits Dying Spy

  6. The Image Understanding Architecture Project

    DTIC Science & Technology

    1988-04-01

    The error resulted in the frame being reduced in size and incorrectly bonded . The problem has been corrected and3 the design has been re-submitted...Promotional literature, Beaverton, OR, 1985. Nii, 1986] Nil, H.P., The Blackboard Model of Problem Solving and the Evolution of Blackboard...microns. This resulted in a reduction in pad sizes to two thirds of the minimum required for safe bonding . All chips had many wire bonds on the die

  7. Status of the MeLoDIE experiment, an advanced device for the study of the irradiation creep of LWR cladding with full online capabilities

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Guimbal, P.; Huotilainen, S.; Taehtinen, S.

    2015-07-01

    As a prototype of future instrumented material experiments in the Jules Horowitz Reactor (JHR), the MELODIE project was launched in 2009 by the CEA in collaboration with VTT. Being designed as a biaxial creep experiment with online capability, MELODIE is able to apply an online-controlled biaxial loading on a LWR clad sample up to 120 MPa and to perform an online measurement of its biaxial deformation. An important experimental challenge was to perform reliably accurate measurements under the high nuclear heat load of in-core locations while keeping within their tight space. For that purpose, specific sensors were co-designed with andmore » built by IFE Halden. Manufacturing of the MELODIE components was completed one year ago. The complexity of its in-pile section and of the pressurization system requested a step-by-step tuning of the setup. The toughest part of this process dealt with the Diameter gauge which required a partial redesign to take into account unexpected and unwanted electromagnetic interactions with the hosting device. Final cold performance tests of the on-board instrumentation will be presented. The MELODIE device is now ready and irradiation should start in OSIRIS reactor this spring. (authors)« less

  8. Seeking an ethical and legal way of procuring transplantable organs from the dying without further attempts to redefine human death

    PubMed Central

    Evans, David Wainwright

    2007-01-01

    Because complex organs taken from unequivocally dead people are not suitable for transplantation, human death has been redefined so that it can be certified at some earlier stage in the dying process and thereby make viable organs available without legal problems. Redefinitions based on concepts of "brain death" have underpinned transplant practice for many years although those concepts have never found universal philosophical acceptance. Neither is there consensus about the clinical tests which have been held sufficient to diagnose the irreversible cessation of all brain function – or as much of it as is deemed relevant – while the body remains alive. For these reasons, the certification of death for transplant purposes on "brain death" grounds is increasingly questioned and there has been pressure to return to its diagnosis on the basis of cardiac arrest and the consequent cessation of blood circulation throughout the body. While superficially a welcome return to the traditional and universally accepted understanding of human death, examination of the protocols using such criteria for the diagnosis of death prior to organ removal reveals a materially different scenario in which the circulatory arrest is not certainly final and purely nominal periods of arrest are required before surgery begins. Recognizing the probably unresolvable conflict between allowing enough time to pass after truly final circulatory arrest for a safe diagnosis of death and its minimization for the sake of the wanted organs, Verheijde and colleagues follow others in calling for the abandonment of the "dead donor rule" and the enactment of legislation to permit the removal of organs from the dying, without pretence that they are dead before that surgery. While it may be doubted whether such a "paradigm change" in the ethics of organ procurement would be accepted by society, their call for its consideration as a fully and fairly informed basis for organ donation is to be applauded. PMID:17603889

  9. Insights into the factors associated with achieving the preference of home death in terminal cancer: A national population-based study.

    PubMed

    Bannon, Finian; Cairnduff, Victoria; Fitzpatrick, Deirdre; Blaney, Janine; Gomes, Barbara; Gavin, Anna; Donnelly, Conan

    2017-11-23

    Most terminally ill cancer patients prefer to die at home, yet only a minority are able to achieve this. Our aim was to investigate the factors associated with cancer patients achieving their preference to die at home. This study took the form of a mortality followback, population-based, observational survey of the relatives of deceased cancer patients in Northern Ireland. Individuals who registered the death of a friend or relative (aged ≥ 18 years) between 1 December 2011 and 31 May 2012, where the primary cause of death was cancer (ICD10: C00-D48), who were invited to take part. Preferred and actual place of death, and patient, service, and clinical data were collected using the QUALYCARE postal questionnaire. Multivariable logistic regression was employed to investigate the factors associated with achieving a home death when preferred. Some 467 of 1,493 invited informants completed the survey. The 362 (77.5%) who expressed a preference for dying at home and spent time at home in their final 3 months were included in our analysis. Of these, 53.4% achieved their preference of a home death. Factors positively associated with achieving a home death were: living in an affluent area, receipt of good and satisfactory district nurse care, discussing place of death with health professionals, and the caregiver's preference for a home death. Being older than 80 years of age, being a Presbyterian, and being unconscious most of the time during their final week were negatively associated with achieving a home death. Communication, care satisfaction, and caregiver preferences were all associated with home death. Our findings will help inform the design of future interventions aimed at increasing the proportion of patients achieving their preferred place of death at home, for example, by targeting interventions toward older patients and those from the most deprived communities.

  10. Incidence of Suicide Among Persons Who Had a Parent Who Died During Their Childhood: A Population-Based Cohort Study.

    PubMed

    Guldin, Mai-Britt; Li, Jiong; Pedersen, Henrik Søndergaard; Obel, Carsten; Agerbo, Esben; Gissler, Mika; Cnattingius, Sven; Olsen, Jørn; Vestergaard, Mogens

    2015-12-01

    Parental death from suicide is associated with increased risk of suicide in the bereaved child, but little is known about the long-term risks of suicide after parental death from other causes. A better understanding of this association may improve suicide prevention efforts. To examine the long-term risks of suicide after parental death and how the risk trajectories differed by cause of parental death while accounting for major potential confounding variables. A population-based matched cohort study was performed using information from nationwide registers (data from 1968 to 2008) in 3 Scandinavian countries (for a total of 7,302,033 persons). We identified 189,094 children (2.6%) who had a parent who died before the child reached 18 years of age (ie, the bereaved cohort). Each bereaved child was matched by sex and age to 10 children who did not have a parent who died before they reached 18 years of age (for a total of 1,890,940 children) (ie, the reference cohort). Both cohorts were followed for up to 40 years. Poisson regression was used to calculate the incidence rate ratio (IRR), while accounting for age at parental death, sex, time since bereavement, maternal/paternal death, birth order, family history of psychiatric illness, and socioeconomic status. Data analyses were finalized June 24, 2015. The main exposure was death of a parent within the first 18 years of life. Incidence of suicide among persons who had a parent who died during their childhood. During follow-up, 265 bereaved persons (0.14%) and 1342 nonbereaved persons (0.07%) died of suicide (IRR = 2.02 [95% CI, 1.75-2.34]); IRR = 3.44 (95% CI, 2.61-4.52) for children who had a parent who died of suicide, and IRR = 1.76 (95% CI, 1.49-2.09) for children who had a parent who died of other causes. The IRR tended to be higher for children who had a parent who died before they reached 6 years of age, and the IRR remained high for at least 25 years. During 25 years of follow-up, the absolute risk of suicide was 4 in 1000 persons for boys who experienced parental death and 2 in 1000 persons for girls who experienced parental death. Parental death in childhood is, irrespective of cause, associated with an increased long-term risk of suicide. The consequences of parental death in childhood are far-reaching, and suicide risk trajectories may be influenced by early-life conditions. Future public health efforts should consider helping highly distressed children to cope with bereavement.

  11. Radiation Hardened Telerobotic Dismantling System Development Final Report CRADA No. TC-1340-96

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Smith, C.; Lightman, A.

    This project was a collaborative effort between the University of California, LLNL and RedZone Robotics, Inc. for the development of radiation-hardened telerobotic dismantling systems for use in applications such as nuclear facility remediation, nuclear accident response, and Chemobyltype remediation. The project supported the design, development, fabrication and testing of a Ukrainian robotic systems. The project was completed on time and within budget. All deliverables were completed. The final project deliverables were consistent with the plans developed in the original project with the exception that the fabricated systems remained in Ukraine.

  12. Final Technical Report- Virginia Solar Pathways Project

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bond, Katharine; Cosby, Sarah

    This Report provides a technical review of the final results of a funding award to Virginia Electric and Power Company (Dominion Energy Virginia (DEV) or the Company) for a project under the U.S. Department of Energy’s Solar Energy Technologies Office. The three-year project was formally known as the Virginia Solar Pathways Project (VSPP or the Project). The purpose of the VSPP was to develop a collaborative utility-administered solar strategy (Solar Strategy) for DEV’s service territory in the Commonwealth that could serve as a replicable model for other states with similar policy environments.

  13. Optimization of Squeeze Casting for Aluminum Alloy Parts

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    David Schwam; John F. Wallace; Qingming Chang

    2002-07-30

    This study was initiated with the installation of a new production size UBE 350 Ton VSC Squeeze Casting system in the Metal Casting Laboratory at Case Western University. A Lindberg 75k W electrical melting furnace was installed alongside. The challenge of installation and operation of such industrial-size equipment in an academic environment was met successfully. Subsequently, a Sterling oil die heater and a Visi-Track shot monitoring system were added. A significant number of inserts were designed and fabricated over the span of the project, primarily for squeeze casting different configurations of test bars and plates. A spiral ''ribbon insert'' formore » evaluation of molten metal fluidity was also fabricated. These inserts were used to generate a broad range of processing conditions and determine their effect on the quality of the squeeze cast parts. This investigation has studied the influence of the various casting variables on the quality of indirect squeeze castings primarily of aluminum alloys. The variables studied include gating design, fill time and fill patter, metal pressure and die temperature variations. The quality of the die casting was assessed by an analysis of both their surface condition and internal soundness. The primary metal tested was an aluminum 356 alloy. In addition to determining the effect of these casting variables on casting quality as measured by a flat plate die of various thickness, a number of test bar inserts with different gating designs have been inserted in the squeeze casting machine. The mechanical properties of these test bars produced under different squeeze casting conditions were measured and reported. The investigation of the resulting properties also included an analysis of the microstructure of the squeeze castings and the effect of the various structural constituents on the resulting properties. The main conclusions from this investigation are as follows: The ingate size and shape are very important since it must remain open until the casting is solidified and pressure is maintained on the solidifying casting. Fanned gates, particularly on the smaller section castings avoid jetting effects at the ingate end. The fan type ingate helps accomplish a rapid fill without high velocities. The molten metal has to fill the cavity before localized solidification occurs. This is best accomplished with a larger ingate to attain rapid filling without excessive velocity or jetting that occurs at high metal velocities. Straight gates are prone to case jetting of the metal stream even a low velocities. Fanned gates allow use of higher fill velocity without excessive jetting. A higher metal pressure provides a more complete fill of the die including improved compensation for solidification shrinkage. With the proper filling pattern, ingates, overflows and die temperature for a given die, very good tensile properties can be attained in squeeze casting. In general, the smaller squeeze castings require higher die temperatures. Computer models using the UES Procast and MagmaSoft finite element software can, after suitable adjustments, predict the flow pattern in the die cavity.« less

  14. Water Resources Research Grant Program project descriptions, fiscal year 1987

    USGS Publications Warehouse

    ,

    1987-01-01

    This report contains information on the 34 new projects funded by the United States Geological Survey 's Water Resources Research Grant Program in fiscal year 1987 and on 3 projects completed during the year. For the new projects, the report gives the grant number, project title, performing organization, principal investigator(s), and a project description that includes: (1) identification of water related problems and problem-solution approach (2) contribution to problem solution, (3) objectives, and (4) approach. The 34 projects include 12 in the area of groundwater quality problems, 12 in the science and technology of water quality management, 1 in climate variability and the hydrologic cycle, 4 in institutional change in water resources management, and 5 in surface water management. For the three completed projects, the report furnishes the grant number; project title; performing organization; principal investor(s); starting data; data of receipt of final report; and an abstract of the final report. Each project description provides the information needed to obtain a copy of the final report. The report contains tables showing: (1) proposals received according to area of research interest, (2) grant awards and funding according to area of research interest, (3) proposals received according to type of submitting organization, and (4) awards and funding according to type of organization. (Author 's abstract)

  15. Khattab (1969-2002)

    DTIC Science & Technology

    2015-02-01

    excellence. He was born in Saudi Arabia and took up jihad first in Afghanistan, then in Tajikistan and Dagestan, and finally in Chechnya , where he devoted...most of his political and militant energy and where he died. In the mid-1990s, he became the leader of the Arab Ansar in Chechnya , and he had his...Tajiks, Afghans and Uzbeks, who joined his group in Chechnya to fight against the Russians. He was keen to understand the culture of the places in

  16. Application Specific Electronic Module Program (ASEM), Final Technical Report.

    DTIC Science & Technology

    1994-12-14

    relatively high temperatures , may induce a metal break or other continuity problems. Secondly, the improved electrical environment at the module level vs...wafer probe can permit higher speed tests to be applied, isolating marginal die. Thirdly, high reliability screens, such as temperature cycling, bum-in...The high temperature aging is done at 150’ C for 500 hours. The thermal cycle treatments are from 0- 100 0 C and 3 cycles per hour are done. The

  17. Transport Experiments on Topological Insulators

    DTIC Science & Technology

    2016-08-16

    neutral currents as well. In insulating magnets, the heat current below 2 K is largely carried by spin waves or magnons (phonons die out rapidly below 2 K...Ong’s group recently showed that  leads to prominent effects on neutral currents as well. In insulating magnets, the heat current below 2 K is...UU UU UU 16-08-2016 15-Sep-2011 14-Oct-2014 Final Report: Transport Experiments on Topological Insulators The views, opinions and/or findings contained

  18. Patterns of Change in User-Generated Social Media Behavior among Service Members Who Die by Suicide

    DTIC Science & Technology

    2016-05-01

    communications about physiological indicators of autonomic arousal (e.g., pain, insomnia) occur independent of internal psychological states. Finally, in the...privacy settings to determine if observed change patterns are generalizable to the larger community of social media users, as opposed to the subgroup who...suicidal intent in the time leading up to their deaths (Busch, Fawcett, & Jacobs, 2003; Coombs et al., 1992; Hall, Platt, & Hall, 1999; Kovacs, Beck

  19. Immune-mediated hemolytic anemia: understanding the nemesis.

    PubMed

    McCullough, Sheila

    2003-11-01

    IMHA is one of the most common causes of anemia in small animals. Although treatment may be rewarding, many patients do not respond adequately to glucocorticoids alone and require additional immunosuppressive therapy. Some patients may succumb to acute severe anemia and die within the first few weeks of treatment; even if they survive, relapses may occur. IMHA is the nemesis; as our understanding of this disease increases and treatment options expand, it is hoped that survival rates will finally improve.

  20. Effects of forming temperature and sintering rate to the final properties of FeCuAl powder compacts formed through uniaxial die compaction process

    NASA Astrophysics Data System (ADS)

    Rahman, M. M.; Ismail, M. A.; Sopyan, I.; Rahman, H. Y.

    2018-01-01

    This paper presents the outcomes of an experimental investigation on the effects of forming temperature and sintering schedule to the final characteristics of FeCuAl powder mass formed at different temperature and sintered at different schedule. A lab-scale uni-axial die compaction rig was designed and fabricated which enabled the compaction of powder mass at room temperature as well as elevated temperature. Iron (Fe) powder ASC 100.29 was mechanically mixed with other elemental powders, namely copper (Cu), and aluminum (Al) for 60 minutes and compacted at three different temperature, i.e., 30°C, 150°C, and 200°C by applying 425 MPa of simultaneous downward and upward axial loading to generate green compacts. The as-pressed samples were inspected visually and the defect-free green compacts were subsequently sintered in an argon gas fired furnace at 800°C for 60 min at three different heating/cooling rates, i.e., 5, 10, and 15°C/min, respectively. The sintered samples were then characterised for their physical, electrical, and mechanical properties. The microstructures of the sintered samples were also analysed. The results revealed that a forming temperature of 150°C and a sintering rate of 10°C/min could produce a product with better characteristics.

  1. Effects of Process Parameters on Copper Powder Compaction Process Using Multi-Particle Finite Element Method

    NASA Astrophysics Data System (ADS)

    Güner, F.; Sofuoğlu, H.

    2018-01-01

    Powder metallurgy (PM) has been widely used in several industries; especially automotive and aerospace industries and powder metallurgy products grow up every year. The mechanical properties of the final product that is obtained by cold compaction and sintering in powder metallurgy are closely related to the final relative density of the process. The distribution of the relative density in the die is affected by parameters such as compaction velocity, friction coefficient and temperature. Moreover, most of the numerical studies utilizing finite element approaches treat the examined environment as a continuous media with uniformly homogeneous porosity whereas Multi-Particle Finite Element Method (MPFEM) treats every particles as an individual body. In MPFEM, each of the particles can be defined as an elastic- plastic deformable body, so the interactions of the particles with each other and the die wall can be investigated. In this study, each particle was modelled and analyzed as individual deformable body with 3D tetrahedral elements by using MPFEM approach. This study, therefore, was performed to investigate the effects of different temperatures and compaction velocities on stress distribution and deformations of copper powders of 200 µm-diameter in compaction process. Furthermore, 3-D MPFEM model utilized von Mises material model and constant coefficient of friction of μ=0.05. In addition to MPFEM approach, continuum modelling approach was also performed for comparison purposes.

  2. Advance care planning and end-of-life care in a network of rural Western Australian hospitals.

    PubMed

    Auret, Kirsten; Sinclair, Craig; Averill, Barbara; Evans, Sharon

    2015-08-01

    To provide a current perspective on end-of-life (EOL) care in regional Western Australia, with a particular focus on the final admission prior to death and the presence of documented advance care planning (ACP). Retrospective medical notes audit. One regional hospital (including colocated hospice) and four small rural hospitals in the Great Southern region of Western Australia. Ninety recently deceased patients, who died in hospitals in the region. Fifty consecutive patients from the regional hospital and 10 consecutive patients from each of the four rural hospitals were included in the audit. A retrospective medical notes audit was undertaken. A 94-item audit tool assessed patient demographics, primary diagnosis, family support, status on admission and presence of documented ACP. Detailed items described the clinical care delivered during the final admission, including communication with family, referral to palliative care, transfers, medical investigations, medical treatments and use of EOL care pathways. Fifty-two per cent were women; median age was 82 years old. Forty per cent died of malignancy. Median length of stay was 7 days. Thirty-nine per cent had formal or informal ACP documented. Rural hospitals performed comparably with the regional hospital on all measures. This study provides benchmarking information that can assist other rural hospitals and suggests ongoing work on optimal methods of measuring quality in EOL care. © 2015 National Rural Health Alliance Inc.

  3. Watchful waiting and active surveillance approach in patients with low risk localized prostatic cancer: an experience of out-patients clinic with 12-year follow-up.

    PubMed

    Kravchick, Sergey; Peled, Ronit; Cytron, Shmuel

    2011-12-01

    In this study we evaluated the safety of expectant approach in the patients with low risk prostate cancer in the reality of community based out-patients clinics. 48 men were enrolled into the study. The inclusion criteria were age ranged from 60 to 75 years and the Epstein criteria for low risk prostate cancer. Patients were managed expectantly while curative treatment was offered when indicated. Initial and final Charlson comorbidity index (CCI) and BMI were assessed for all men. Patients' median follow-up was 81.1 ± 29.1 years. During this study 41.7% of the patients chose active forms of treatment. Cancer was found in 20.8% (n-10) of our patients. Two first sessions of re-biopsy diagnosed 92% of T1c upgrading. Six men with CCI ≥2 died from concomitant disease and no one died from PCa. Significant correlation was found between BMI and final CCI ≥2 (p-0.001). Expectant approach can be considered as self alternative to active treatment model in selected group of patients with well differentiated PCa, however 20.8% of these patients are still at risk of having aggressive form of cancer. Expectant approach is particular beneficial for the patients with CCI 1-2 and high BMI.

  4. Chrysler Upset Protrusion Joining Techniques for Joining Dissimilar Metals

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Logan, Stephen

    The project goal was to develop and demonstrate a robust, cost effective, and versatile joining technique, known as Upset Protrusion Joining (UPJ), for joining challenging dissimilar metal com-binations, especially those where one of the metals is a die cast magnesium (Mg) component. Since two of the key obstacles preventing more widespread use of light metals (especially in high volume automotive applications) are 1) a lack of robust joining techniques and 2) susceptibility to galvanic corrosion, and since the majority of the joint combinations evaluated in this project include die cast Mg (the lightest structural metal) as one of the twomore » materials being joined, and since die casting is the most common and cost effective process for producing Mg components, then successful project completion provides a key enabler to high volume application of lightweight materials, thus potentially leading to reduced costs, and encouraging implementation of lightweight multi-material vehicles for significant reductions in energy consumption and reduced greenhouse gas emissions. Eco-nomic benefits to end-use consumers are achieved primarily via the reduction in fuel consumption. Unlike currently available commercial processes, the UPJ process relies on a very robust mechanical joint rather than intermetallic bonding, so the more cathodic material can be coated prior to joining, thus creating a robust isolation against galvanic attack on the more anodic material. Additionally, since the UPJ protrusion is going through a hole that can be pre-drilled or pre-punched prior to coating, the UPJ process is less likely to damage the coating when the joint is being made. Further-more, since there is no additional cathodic material (such as a steel fastener) used to create the joint, there is no joining induced galvanic activity beyond that of the two parent materials. In accordance with its originally proposed plan, this project has successfully developed process variants of UPJ to enable joining of Mg die castings to aluminum (Al) and steel sheet components of various thicknesses, strengths and coating configurations. While most development focused on the simpler round boss version of the process, an additional phase of the work focused on devel-opment of an oval boss version to support applications with narrow flanges, while yet another vari-ant of the process, known as Upset Cast Riveting (UCR), was developed and evaluated for joining mixed metals that may not necessarily include Mg or Al die cast components. Although each varia-tion posed unique challenges described later in the report, all variations were successfully produced and evaluated, and each could be further developed for specific types of commercial applications. In this project, UPJ performed favorably against the benchmark self-pierce riveting (SPR) process in Mg AM60B to Al 6013 combinations although significant corrosion challenges were observed in both processes, especially for the bare Mg to bare Al configurations. Additional challenges were observed in joining Mg to steel with the UPJ process (SPR was not evaluated for this combination as it was not considered viable). To pass FCA’s specified corrosion tests with Mg/steel combina-tions, new steel treatments were evaluated, as well as adhesives and sealed edges. These showed significant improvement. In general, UPJ performed very well in Mg to Al 6016 combinations, even in corrosion evaluation of the bare Mg to bare Al configuration (again, SPR was not evaluated for this material combination as the 1.1 mm thick Al6016 sheet thickness was considered too thin for the SPR process). The improvement in corrosion performance of the Mg to Al 6016 combina-tion over the Mg to Al 6013 combination was thought to be a result of the lower copper content in the Al 6016 alloy. Oval boss joints showed substantial improvement in all joint strength criteria compared to 8.0-mm diameter round boss joints but were not evaluated for corrosion performance. The improved joint strength is likely a result of larger shear area. Cosmetic corrosion performance of all test assemblies (UPJ, UCR and SPR) was a challenge due to exposed edges and crevices al-lowing undercutting of the coatings. In real world component applications, the exposed edges, so prevalent on the joining test coupons, would be less prevalent and easier to protect.« less

  5. Use of Medications of Questionable Benefit During the Last Year of Life of Older Adults With Dementia.

    PubMed

    Morin, Lucas; Vetrano, Davide L; Grande, Giulia; Fratiglioni, Laura; Fastbom, Johan; Johnell, Kristina

    2017-06-01

    To investigate the prevalence and factors associated with the use of medications of questionable benefit throughout the final year of life of older adults who died with dementia. Register-based, longitudinal cohort study. Entire Sweden. All older adults (≥75 years) who died with dementia between 2007 and 2013 (n = 120,067). Exposure to medications of questionable benefit was calculated for each of the last 12 months before death, based on longitudinal data from the Swedish Prescribed Drug Register. The proportion of older adults with dementia who received at least 1 medication of questionable benefit decreased from 38.6% 12 months before death to 34.7% during the final month before death (P < .001 for trend). Among older adults with dementia who used at least 1 medication of questionable benefit 12 months before death, 74.8% remained exposed until their last month of life. Living in an institution was independently associated with a 15% reduction of the likelihood to receive ≥1 medication of questionable benefit during the last month before death (odds ratio 0.85, 95% confidence interval 0.88-0.83). Antidementia drugs accounted for one-fifth of the total number of medications of questionable benefit. Lipid-lowering agents were used by 8.3% of individuals during their final month of life (10.2% of community-dwellers and 6.6% of institutionalized people, P < .001). Clinicians caring for older adults with advanced dementia should be provided with reliable tools to help them reduce the burden of medications of questionable benefit near the end of life. Copyright © 2017 AMDA – The Society for Post-Acute and Long-Term Care Medicine. Published by Elsevier Inc. All rights reserved.

  6. Hazardous thunderstorm intensification over Lake Victoria

    PubMed Central

    Thiery, Wim; Davin, Edouard L.; Seneviratne, Sonia I.; Bedka, Kristopher; Lhermitte, Stef; van Lipzig, Nicole P. M.

    2016-01-01

    Weather extremes have harmful impacts on communities around Lake Victoria, where thousands of fishermen die every year because of intense night-time thunderstorms. Yet how these thunderstorms will evolve in a future warmer climate is still unknown. Here we show that Lake Victoria is projected to be a hotspot of future extreme precipitation intensification by using new satellite-based observations, a high-resolution climate projection for the African Great Lakes and coarser-scale ensemble projections. Land precipitation on the previous day exerts a control on night-time occurrence of extremes on the lake by enhancing atmospheric convergence (74%) and moisture availability (26%). The future increase in extremes over Lake Victoria is about twice as large relative to surrounding land under a high-emission scenario, as only over-lake moisture advection is high enough to sustain Clausius–Clapeyron scaling. Our results highlight a major hazard associated with climate change over East Africa and underline the need for high-resolution projections to assess local climate change. PMID:27658848

  7. 'Advancement of KHPS to DOE TRL 7/8' Project - Final Technical Report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Adonizio, Mary Ann; Corren, Dean; Smith, Ron

    Final Report describing activities performed under the 'Advancement of the KHPS to DOE TRL 7/8' project, including the development of critical component test protocols, testing and analysis of the Gen5 KHPS main shaft seal, and continuing compliance work on approved operational environmental monitoring plans in anticipation of KHPS turbine installation at Verdant Power's Roosevelt Island Tidal Energy (RITE) Project site in New York, NY.

  8. Jobs and Self-Sufficiency: Goals of the Project, "Technical Support Services to the Developmentally Disabled, Region III." Final Report, October 1976 to September 1979.

    ERIC Educational Resources Information Center

    Mallik, Kalisankar; Shaver, Elaine M.

    The final report of a 3 year project to improve the quality of life of mentally retarded, cerebral palsied, and epileptic persons in Region III is presented. The first section details the efforts of the project staff in providing competitive employment opportunities or sheltered employment for 40 severely disabled persons. Equipment modification…

  9. The Institute for Sustained Performance, Energy, and Resilience, University of North Carolina, Final Technical Report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Fowler, Robert

    This is the final report for the UNC component of the SciDAD Institute for Sustained Performance, Energy, and Resilience. In this report, we describe activities on the SUPER project at RENCI at the University of North Carolina at Chapel Hill. While we focus particularly on UNC, we touch on project-wide activities as well as, on interactions with, and impacts on, other projects.

  10. 75 FR 19670 - Notice of Availability of the Record of Decision for the I-65 to US 31W Access Improvement Final...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-15

    ...)] Notice of Availability of the Record of Decision for the I-65 to US 31W Access Improvement Final... implement the I-65 to US 31W Access Improvement project in Warren County, Kentucky. The Division... US 31W Access Improvement project can be viewed and downloaded from the project Web site at http...

  11. National Community Solar Platform

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Rupert, Bart

    This project was created to provide a National Community Solar Platform (NCSP) portal known as Community Solar Hub, that is available to any entity or individual who wants to develop community solar. This has been done by providing a comprehensive portal to make CEC’s solutions, and other proven community solar solutions, externally available for everyone to access – making the process easy through proven platforms to protect subscribers, developers and utilities. The successful completion of this project provides these tools via a web platform and integration APIs, a wide spectrum of community solar projects included in the platform, multiple groupsmore » of customers (utilities, EPCs, and advocates) using the platform to develop community solar, and open access to anyone interested in community solar. CEC’s Incubator project includes web-based informational resources, integrated systems for project information and billing systems, and engagement with customers and users by community solar experts. The combined effort externalizes much of Clean Energy Collective’s industry-leading expertise, allowing third parties to develop community solar without duplicating expensive start-up efforts. The availability of this platform creates community solar projects that are cheaper to build and cheaper to participate in, furthering the goals of DOE’s SunShot Initiative. Final SF 425 Final SF 428 Final DOE F 2050.11 Final Report Narrative« less

  12. S.R. 0202, Section 404, intelligent transportation systems (ITS) deployment : final report

    DOT National Transportation Integrated Search

    2005-06-01

    This document serves as FHWAs Final Report for the SR 0202, Section 404 ITS project. At the time of its deployment, this project represented the largest ITS deployment to date in the Philadelphia metropolitan area and the Commonwealth of Pennsylva...

  13. Arizona Deafblind Project, 1995-1999. Final Report.

    ERIC Educational Resources Information Center

    Arizona State School for the Deaf and Blind, Tucson.

    This final report describes accomplishments of the four-year federally funded Arizona Deafblind Project which attempted to: (1) identify all deafblind children in Arizona; (2) deliver technical assistance to families; (3) deliver technical assistance to service providers; and (4) enhance community oversight, coordination, and collaboration with…

  14. Horticulture Therapy Curriculum Development. Final Report.

    ERIC Educational Resources Information Center

    Taylor, Sally; And Others

    This final report includes two major components: a narrative describing a project at Edmonds Community College, Washington, to develop a horticultural therapy curriculum and descriptions of six courses developed or revised during the project. The narrative reports the development of a supplementary interdisciplinary certification program to train…

  15. Reducing school bus/light-vehicle conflicts through connected vehicle communications : final report.

    DOT National Transportation Integrated Search

    2016-09-15

    This project aimed to develop and test a concept for improving the safety of school bus transportation using connected vehicle technology. The project consisted of three key steps that led to a final road study: 1) conducting focus groups with light ...

  16. 78 FR 34897 - Final Priorities; National Institute on Disability and Rehabilitation Research-Disability and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-11

    ....133E-8.] Final Priorities; National Institute on Disability and Rehabilitation Research--Disability and Rehabilitation Research Projects and Centers Program--Rehabilitation Engineering Research Centers AGENCY: Office... under the Disability and Rehabilitation Research Projects and Centers Program administered by the...

  17. Advanced Air Transportation Technologies Project, Final Document Collection

    NASA Technical Reports Server (NTRS)

    Mogford, Richard H.; Wold, Sheryl (Editor)

    2008-01-01

    This CD ROM contains a compilation of the final documents of the Advanced Air Transportation Technologies (AAIT) project, which was an eight-year (1996 to 2004), $400M project managed by the Airspace Systems Program office, which was part of the Aeronautics Research Mission Directorate at NASA Headquarters. AAIT focused on developing advanced automation tools and air traffic management concepts that would help improve the efficiency of the National Airspace System, while maintaining or enhancing safety. The documents contained in the CD are final reports on AAIT tasks that serve to document the project's accomplishments over its eight-year term. Documents include information on: Advanced Air Transportation Technologies, Autonomous Operations Planner, Collaborative Arrival Planner, Distributed Air/Ground Traffic Management Concept Elements 5, 6, & 11, Direct-To, Direct-To Technology Transfer, Expedite Departure Path, En Route Data Exchange, Final Approach Spacing Tool - (Active and Passive), Multi-Center Traffic Management Advisor, Multi Center Traffic Management Advisor Technology Transfer, Surface Movement Advisor, Surface Management System, Surface Management System Technology Transfer and Traffic Flow Management Research & Development.

  18. Life expectancy and health care expenditures: a new calculation for Germany using the costs of dying.

    PubMed

    Breyer, Friedrich; Felder, Stefan

    2006-01-01

    Some people believe that the impact of population ageing on future health care expenditures will be quite moderate due to the high costs of dying. If not age per se but proximity to death determines the bulk of expenditures, a shift in the mortality risk to higher ages will not affect lifetime health care expenditures as death occurs only once in every life. We attempt to take this effect into account when we calculate the demographic impact on health care expenditures in Germany. From a Swiss data set, we derive age-expenditure profiles for both genders, separately for persons in their last 4 years of life and for survivors, which we apply to the projections of the age structure and mortality rates for the German population between 2002 and 2050 as published by the Statistische Bundesamt. In the extreme case, we assume that morbidity is compressed at the end of life in such a way that a 60-year old in 2050 is as healthy as a 56-year old today if his life expectancy is 4 years higher. We calculate that at constant prices, per-capita health expenditures of Social Health Insurance would rise from 2596 Euro in 2002 to between 2959 Euro and 3102 Euro in 2050 when only the age structure of the population changes and everything else remains constant at the present level, and to between 5232 Euro and 5485 Euro with a technology-driven exogenous cost increase of 1% per annum. A "naïve" projection based only on the age distribution of health care expenditures, but not distinguishing between survivors and decedents, yields values of 3217 Euro and 5688 Euro for 2050, respectively. Thus, the error of excluding the "costs of dying" effect is small compared with the error of underestimating the financial consequences of expanding medical technology.

  19. WA50 We can't do it alone: hospices and schools working together to educate and support children around death, dying and bereavement.

    PubMed

    Paul, Sally; Quinn, Helen

    2015-04-01

    Educating and supporting children around death, dying and bereavement, in schools, frequently relies on the individual interest and expertise of staff (Rowling 2003). Moves to develop such work of ten results in one off projects led by external agencies. Support and education is therefore ad hoc and unequitable. A research study was undertaken between a hospice and school to develop practice in this area from a health promotion perspective. This presentation discusses the design and implementation of two practice innovations arising from this process. The innovations aimed to introduce and educate children on issues related to loss and change, whilst simultaneously ensure that school staff have the skills and confidence to support individual experiences within the school setting. This was from a harm education and early intervention standpoint. Collaborative inquiry, within an action research methodology, was used to advance the innovations. This involved school and hospice staff working together to design and facilitate the activities. A programme of activities for children aged 5 to 11 (the resilience project) was designed and integrated throughout the curriculum. This is currently being piloted. A bereavement training programme was designed and facilitated to all school staff. Evaluations reported an increase in confidence around supporting bereavement issues. The process highlighted that combing the skills and expertise of hospice and school staff was essential in developing sustainable activities, appropriate to the setting. The role of the hospice in engaging with communities to collaboratively develop education and support around death, dying and bereavement was emphasised. Rowling, L. Grief in school communities: effective support strategies. Buckingham and Philadelphia: Open University Press, 2003. © 2015, Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

  20. Kokua Mau: a statewide effort to improve end-of-life care.

    PubMed

    Braun, Kathryn L; Zir, Ana; Crocker, Joanna; Seely, Marilyn R

    2005-04-01

    Many Americans die in pain, without hospice, and without regard to advance directives, suggesting a need to improve end-of-life (EOL) awareness and services. This paper describes Kokua Mau, a community-state partnership to improve EOL in Hawaii funded by The Robert Wood Johnson Foundation (RWJF). Coalition activities were guided by innovation-diffusion theory, targeting "innovators" and "change agents" within communities and organizations willing to learn about and facilitate improvements to EOL care. Evaluation of a community-wide intervention to improve EOL care. Honolulu, Hawaii. We tracked dissemination of campaign messages by counting numbers of coalition members (including innovators and change agents to carry on the work), individuals reached through awareness and educational offerings, and new EOL projects initiated during and after the initial 3-year RWJF funding. To measure change, we counted the number of legislative policies that were modified by the coalition as well as indicators of hospice utilization, advance directive (AD) completion, support for physician-assisted death, and place of death. In the first 3 years of the project: coalition membership grew to 350 members; EOL care curricula were developed and offered to various target audiences; 17,000 individuals attended educational events; policy changes were facilitated; decreases were seen in proportions of residents supporting physician-assisted suicide; and increases were seen in advance directive completion rates and hospice utilization. Most importantly, after the grant period, coalition members went on to develop and implement new programs to improve care to the dying. Although it will take several years to effect comprehensive and sustained changes in the way death is perceived and the dying process is facilitated, findings suggest that programs based on innovation-diffusion theory can increase EOL awareness and help develop the change agents and role models needed to affect community-wide change over the long term.

  1. Earth Observations by the Expedition 19 crew

    NASA Image and Video Library

    2009-05-07

    ISS019-E-014918 (7 May 2009) --- Saint Helena Island is featured in this image photographed by an Expedition 19 crewmember on the International Space Station. This isolated island, located in the South Atlantic Ocean approximately 1860 kilometers to the west of the African coastline, is perhaps best known as the final resting place of Napoleon Bonaparte I of France. Bonaparte was exiled to the island following his defeat at the Battle of Waterloo in 1815; he died on the island six years later in 1821. Today, the island is a British Overseas Territory, with access provided thirty times a year by a single ship, the RMS St. Helena. The rugged topography evident in this photograph is the result of erosion of the volcanic rocks that make up the island into sharp peaks and deep ravines. A climatic gradient related to elevation is also evident ? the higher, wetter central portion of the island is covered with green vegetation, whereas the lower coastal areas are drier and hotter with little vegetation cover. Human presence on the island has also caused dramatic changes to the original flora and fauna of the island. Only approximately 10 percent of the forest cover observed by the first explorers now remains in a semi-natural state, and that is concentrated in the interior highlands. Saint Helena Island was also visited by Charles Darwin during his scientific voyages in the 19th century. He visited the island in 1836 aboard HMS Beagle, recording observations of the flora, fauna, and geology that would inform his theory of evolution. This image was acquired by crew members onboard the International Space Station as part of an ongoing project (the HMS Beagle Project) to document current biodiversity in areas visited by Charles Darwin.

  2. Impact of process conditions on the density and durability of wheat, oat, canola, and barley straw briquettes

    DOE PAGES

    Tumuluru, J. S.; Tabil, L. G.; Song, Y.; ...

    2014-10-01

    The present study is to understand the impact of process conditions on the quality attributes of wheat oat, barley, and canola straw briquettes. Analysis of variance indicated that briquette moisture content and initial density immediately after compaction and final density after 2 weeks of storage are strong functions of feedstock moisture content and compression pressure, whereas durability rating is influenced by die temperature and feedstock moisture content. Briquettes produced at a low feedstock moisture content of 9 % (w.b.) yielded maximum densities >700 kg/m3 for wheat, oat, canola, and barley straws. Lower feedstock moisture content of <10 % (w.b.) andmore » higher die temperatures >110 °C and compression pressure >10 MPa minimized the briquette moisture content and maximized densities and durability rating based on surface plots observations. Optimal process conditions indicated that a low feedstock moisture content of about 9 % (w.b.), high die temperature of 120–130 °C, medium-to-large hammer mill screen sizes of about 24 to 31.75 mm, and low to high compression pressures of 7.5 to 12.5 MPa minimized briquette moisture content to <8 % (w.b.) and maximized density to >700 kg/m3. Durability rating >90 % is achievable at higher die temperatures of >123 °C, lower to medium feedstock moisture contents of 9 to 12 % (w.b.), low to high compression pressures of 7.5 to 12.5 MPa, and large hammer mill screen size of 31.75 mm, except for canola where a lower compression pressure of 7.5 to 8.5 MPa and a smaller hammer mill screen size of 19 mm for oat maximized the durability rating values.« less

  3. Recovery Act-SmartGrid regional demonstration transmission and distribution (T&D) Infrastructure

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hedges, Edward T.

    This document represents the Final Technical Report for the Kansas City Power & Light Company (KCP&L) Green Impact Zone SmartGrid Demonstration Project (SGDP). The KCP&L project is partially funded by Department of Energy (DOE) Regional Smart Grid Demonstration Project cooperative agreement DE-OE0000221 in the Transmission and Distribution Infrastructure application area. This Final Technical Report summarizes the KCP&L SGDP as of April 30, 2015 and includes summaries of the project design, implementation, operations, and analysis performed as of that date.

  4. 77 FR 40601 - Final Priority: Disability and Rehabilitation Research Projects and Centers Program; Disability...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-10

    ... analyses of data, producing observational findings, and creating other sources of research-based... provide a rationale for the stage of research being proposed and the research methods associated with the... DEPARTMENT OF EDUCATION Final Priority: Disability and Rehabilitation Research Projects and...

  5. LSCA Final Reports: Second Series.

    ERIC Educational Resources Information Center

    Clark, Collin, Ed.

    This document includes final summary reports from recent federally funded Library Services and Construction Act (LSCA) demonstration projects in California. While some projects reported at length and others provided the bare facts, reports are excerpted but published as received, without editing beyond a uniform first page. The Summary Report Form…

  6. LSCA Final Reports: Third Series.

    ERIC Educational Resources Information Center

    Clark, Collin, Ed.

    This document includes final summary reports from 16 recent federally funded Library Services and Construction Act (LSCA) projects in California. This volume covers generally the period 1984-85, and reports are presented in six subject areas: programs for children, information and referral projects, institutional services, literacy, local history,…

  7. 37. From Final Construction Report on the Haleakala Road ProjectNR7, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    37. From Final Construction Report on the Haleakala Road Project--NR-7, Hawaii National Park, Island of Maui, Territory of Hawaii. HAND-LAID ROCK BERM ON RETURN CURVE TO PREVENT SCOUR AND SEEPAGE THROUGH FILLS. - Haleakala National Park Roads, Pukalani, Maui County, HI

  8. Wyoming Deaf/Blind Grant. Final Report.

    ERIC Educational Resources Information Center

    Whitson, Joanne B.

    This final report describes activities and accomplishments of the Wyoming Deaf-Blind Grant, a 3-year federally supported project to identify children who have deaf-blindness and to provide technical assistance in the development of educational services for these children. Major accomplishments of the project included: identification of more…

  9. Software Engineering Research/Developer Collaborations in 2005

    NASA Technical Reports Server (NTRS)

    Pressburger, Tom

    2006-01-01

    In CY 2005, three collaborations between software engineering technology providers and NASA software development personnel deployed three software engineering technologies on NASA development projects (a different technology on each project). The main purposes were to benefit the projects, infuse the technologies if beneficial into NASA, and give feedback to the technology providers to improve the technologies. Each collaboration project produced a final report. Section 2 of this report summarizes each project, drawing from the final reports and communications with the software developers and technology providers. Section 3 indicates paths to further infusion of the technologies into NASA practice. Section 4 summarizes some technology transfer lessons learned. Also included is an acronym list.

  10. Who Do We Deploy for Psychological Operations: A Function Profile for TPT Members

    DTIC Science & Technology

    2008-01-01

    doet onderzoek om de ontwikkeling v’an PSYOPS in Nederland te ondersteunen. Een eerste stap, in het goed voorbereiden en uitvoeren van PSYOPS is het...bezit. De focus van het huidige project ligt op de selectiemethode van mensen die PSYOPS functies gaan vervullen. Naast Nederland zijn er ook andere NAVO...deze interviews kwam naar voren dat verschillende landen kampen met dezelfde problemen als Nederland wat betreft de selectie van het PSYOPS personeel

  11. Cultural Resources Survey of the Western Sections of the Larose to Golden Meadow Hurricane Protection Project, Lafourche Parish, Louisiana.

    DTIC Science & Technology

    1986-09-18

    plain, where plant and animal communities are highly sensitive to changes in elevation and salinity , changing shorelines and stream patterns can...material accumulates, shallow bodies of water and intertidal mudflats are created. Along the seaward edge, brackish and saline marshes develop. The...old lobe allow the salinity of inland swamps to increase, causing them to die out. The natural levees of the abandoned distributaries, in the absence

  12. The National Center for Collaboration in Medical Modeling and Simulation

    DTIC Science & Technology

    2006-11-01

    familiarize fractures that occur during fainting spells of patients left students with many procedural details, unattended."," An improperly performed...placed in the (Scerbo, 2005). First, the Visible Human project carotid artery to reduce the possibility of an embolism sponsored by the National Library...telling him that his kidneys were going to lose their ability to function because he was " fat ." He then informed the patient that he was "going to die

  13. Job Oriented Training: Onderwijskundige Grondslag en Onderbouwing (Job Oriented Training: Foundation and Empirical Support)

    DTIC Science & Technology

    2008-07-01

    die binmen defensie tot aanzien van de effecten van JOT onderwijs met het nieuwe leren terug te dan toe in gebruik waren bij het theorie - voeren is op...problemen in de uitvoerings- onderwijs; toepassing van JOT impliceerde Grondslag praktijk van datzeltde regulier onderwijs. dat er geen theorie meer...het rechte eind Opdrachtnummer Datum PROGRAMMA PROJECT juli 2008 Program mabegeleider Projectbegeleider Auteur (s) IkolP.M.. Bonen,dr. A.H. van der

  14. Choosing care homes as the least preferred place to die: a cross-national survey of public preferences in seven European countries.

    PubMed

    Calanzani, Natalia; Moens, Katrien; Cohen, Joachim; Higginson, Irene J; Harding, Richard; Deliens, Luc; Toscani, Franco; Ferreira, Pedro L; Bausewein, Claudia; Daveson, Barbara A; Gysels, Marjolein; Ceulemans, Lucas; Gomes, Barbara

    2014-10-23

    Care homes are increasingly becoming places where people spend the final stages of their lives and eventually die. This trend is expected to continue due to population ageing, yet little is known about public preferences regarding this setting. As part of a larger study examining preferences and priorities for end of life care, we investigated the extent to which care homes are chosen as the least preferred place of death, and the factors associated with this negative preference. We conducted a cross-sectional telephone survey among 9,344 adults from random private households in England, Flanders, Germany, Italy, the Netherlands, Portugal and Spain. We asked participants where they would least prefer to die in a situation of serious illness with less than one year to live. Multivariate binary logistic regressions were used to identify factors associated with choosing care homes as the least preferred place of death in each country. Care homes were the most frequently mentioned least preferred place of death in the Netherlands (41.5%), Italy and Spain (both 36.7%) and the second most frequent in England (28.0%), Portugal (25.8%), Germany (23.7%) and Flanders (18.9%). Only two factors had a similar and significant effect on the least preferred place of death in more than one country. In Germany and the Netherlands those doing housework were less likely to choose care homes as their least preferred place (AOR 0.72; 95% CI:0.54-0.96 and AOR 0.68; 95% CI:0.52-0.90 respectively), while those born in the country where the survey took place were more likely to choose care homes (AOR 1.77; 95% CI:1.05-2.99 and AOR 1.74; 95% CI:1.03-2.95 respectively). Experiences of serious illness, death and dying were not associated with the preference. Our results suggest it might be difficult to promote care homes as a good place to die. This is an urgent research area in order to meet needs and preferences of a growing number of older people with chronic, debilitating conditions across Europe. From a research perspective and in order to allow people to be cared for and die where they wish, our findings highlight the need to build more in depth evidence on reasons underlying this negative preference.

  15. Promoting Effective Transition for Severely Handicapped Youth from School to Work through Training, Intervention, Support and Advocacy. Year 3 and Final Evaluation Report: Project COMPETE, October 1, 1984-September 30, 1987.

    ERIC Educational Resources Information Center

    Gittman, Elizabeth

    The final report describes the objectives and accomplishments of Project COMPETE, a 3-year project in New York State whose purpose was to develop secondary and transitional postsecondary programming for training youth with severe disabilities in skills necessary to achieve a successful transition from school to vocational opportunities in their…

  16. Pilot for Alaska Students with Deaf-Blindness: Inclusion in Regular Classrooms (PALS). Final Performance Report, October 1, 1992 to September 30, 1995.

    ERIC Educational Resources Information Center

    Brown, DiAnn; Maiuri, Fran

    This final report describes a pilot 3-year project in Alaska to include children with deaf-blindness in regular classrooms. The project established and supported two pilot sites for inclusion of students with deaf-blindness, one urban and one rural. As a result of the project, three out of four pilot site students moved from self-contained special…

  17. 78 FR 40545 - Notice of Final Federal Agency Action on Proposed Highway in Georgia the Interstate 75 (I-75...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-05

    .... 139(l)(1). The I-75 Express Lanes Project will design a managed lane system along I-75 from the SR 155..., permits and approvals for the project. DATES: By this notice, the FHWA is advising the public of the final... action on the highway project will be barred unless the claim is filed on or before December 2, 2013. If...

  18. WA22 "it's hard to watch people die for a living": embedding the palliative approach into the organisational culture of long term care homes using participatory action research.

    PubMed

    Kelley, Mary Lou; Kaasalainen, Sharon; McKee, Marg; Marcella, Jill; Gaudet, Alesha; McAnulty, Jessica

    2015-04-01

    Long term care homes (LTC) in Canada have become a major location of death with 20% or more residents dying each year. Given the increasing age and frailty of residents, this is soon expected to increase to 40%. LTC has struggled to incorporate care of the dying into their day to day practice and culture because death is often absent from formalised policy and protocols. This workshop will share resources created during a 5 year participatory action research project in Ontario, Canada that aimed to improve the quality of life of people who were dying in long term care homes. Through staff participation and empowerment, a process of organisational capacity development was undertaken. An extensive needs assessment was followed by creating an interprofessional palliative care resource team within each home. This team assessed the assets and gaps in their home and guided development of education, policy and clinical practices to address needs. Community partners with expertise in palliative care were engaged to support staff. A framework for palliative care in LTC integrates the palliative approach into the residents' journey from admission to death. Resources for organisational change were developed and organised into a toolkit that is unique to the LTC setting and context, and can be accessed at www.palliativealliance.ca The Quality Palliative Care in Long term Care Toolkit is the first of its kind in Canada. The toolkit can guide LTC management and staff through a process of culture change to incorporate a palliative approach to care. © 2015, Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

  19. 77 FR 5505 - Eagle Crest Energy Company; Notice of Availability of the Final Environmental Impact Statement...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-03

    ... Energy Projects has reviewed the application for license for the Eagle Mountain Pumped Storage... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Project No. 13123-002--California] Eagle Crest Energy Company; Notice of Availability of the Final Environmental Impact Statement for the...

  20. Final Evaluation for the Neighborhood Educational Cultural Centerette.

    ERIC Educational Resources Information Center

    Frost, Patricia

    Contained in this report is the final evaluation for the Neighborhood Educational Cultural Centerette Project. Objectives of the research project were to: (1) investigate, experiment with, create, and evaluate methods of instruction curriculum, and materials; analyze pupil learning styles and teacher-teaching styles; and to provide staff growth…

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