Exsanguinated blood volume estimation using fractal analysis of digital images.

PubMed

Sant, Sonia P; Fairgrieve, Scott I

2012-05-01

The estimation of bloodstain volume using fractal analysis of digital images of passive blood stains is presented. Binary digital photos of bloodstains of known volumes (ranging from 1 to 7 mL), dispersed in a defined area, were subjected to image analysis using FracLac V. 2.0 for ImageJ. The box-counting method was used to generate a fractal dimension for each trial. A positive correlation between the generated fractal number and the volume of blood was found (R(2) = 0.99). Regression equations were produced to estimate the volume of blood in blind trials. An error rate ranging from 78% for 1 mL to 7% for 6 mL demonstrated that as the volume increases so does the accuracy of the volume estimation. This method used in the preliminary study proved that bloodstain patterns may be deconstructed into mathematical parameters, thus removing the subjective element inherent in other methods of volume estimation. © 2012 American Academy of Forensic Sciences.

Numerical Flight Mechanics Analysis Of The SHEFEX I Ascent And Re-Entry Phases

NASA Astrophysics Data System (ADS)

Bartolome Calvo, Javier; Eggers, Thino

2011-08-01

The SHarp Edge Flight EXperiment (SHEFEX) I provides a huge amount of scientific data to validate numerical tools in hypersonic flows. These data allow the direct comparison of flight measurements with the current numerical tools available at DLR. Therefore, this paper is devoted to apply a recently developed direct coupling between aerodynamics and flight dynamics to the SHEFEX I flight. In a first step, mission analyses are carried out using the trajectory optimization program REENT 6D coupled to missile DATCOM. In a second step, the direct coupling between the trajectory program and the DLR TAU code, in which the unsteady Euler equations including rigid body motion are solved, is applied to analyze some interesting parts of ascent and re-entry phases of the flight experiment. The agreement of the numerical predictions with the obtained flight data is satisfactory assuming a variable fin deflection angle.

Quantification of gastric emptying and duodenogastric reflux stroke volumes using three-dimensional guided digital color Doppler imaging.

PubMed

Hausken, T; Li, X N; Goldman, B; Leotta, D; Ødegaard, S; Martin, R W

2001-07-01

To develop a non-invasive method for evaluating gastric emptying and duodenogastric reflux stroke volumes using three-dimensional (3D) guided digital color Doppler imaging. The technique involved color Doppler digital images of transpyloric flow in which the 3D position and orientation of the images were known by using a magnetic location system. In vitro, the system was found to slightly underestimate the reference flow (by average 8.8%). In vivo (five volunteers), stroke volume of gastric emptying episodes lasted on average only 0.69 s with a volume on average of 4.3 ml (range 1.1-7.4 ml), and duodenogastric reflux episodes on average 1.4 s with a volume of 8.3 ml (range 1.3-14.1 ml). With the appropriate instrument settings, orientation determined color Doppler can be used for stroke volume quantification of gastric emptying and duodenogastric reflux episodes.

Measurement of limb volume: laser scanning versus volume displacement.

PubMed

McKinnon, John Gregory; Wong, Vanessa; Temple, Walley J; Galbraith, Callum; Ferry, Paul; Clynch, George S; Clynch, Colin

2007-10-01

Determining the prevalence and treatment success of surgical lymphedema requires accurate and reproducible measurement. A new method of measurement of limb volume is described. A series of inanimate objects of known and unknown volume was measured using digital laser scanning and water displacement. A similar comparison was made with 10 human volunteers. Digital scanning was evaluated by comparison to the established method of water displacement, then to itself to determine reproducibility of measurement. (1) Objects of known volume: Laser scanning accurately measured the calculated volume but water displacement became less accurate as the size of the object increased. (2) Objects of unknown volume: As average volume increased, there was an increasing bias of underestimation of volume by the water displacement method. The coefficient of reproducibility of water displacement was 83.44 ml. In contrast, the reproducibility of the digital scanning method was 19.0 ml. (3) Human data: The mean difference between water displacement volume and laser scanning volume was 151.7 ml (SD +/- 189.5). The coefficient of reproducibility of water displacement was 450.8 ml whereas for laser scanning it was 174 ml. Laser scanning is an innovative method of measuring tissue volume that combines precision and reproducibility and may have clinical utility for measuring lymphedema. 2007 Wiley-Liss, Inc

Theoretical design and analysis of multivolume digital assays with wide dynamic range validated experimentally with microfluidic digital PCR.

PubMed

Kreutz, Jason E; Munson, Todd; Huynh, Toan; Shen, Feng; Du, Wenbin; Ismagilov, Rustem F

2011-11-01

This paper presents a protocol using theoretical methods and free software to design and analyze multivolume digital PCR (MV digital PCR) devices; the theory and software are also applicable to design and analysis of dilution series in digital PCR. MV digital PCR minimizes the total number of wells required for "digital" (single molecule) measurements while maintaining high dynamic range and high resolution. In some examples, multivolume designs with fewer than 200 total wells are predicted to provide dynamic range with 5-fold resolution similar to that of single-volume designs requiring 12,000 wells. Mathematical techniques were utilized and expanded to maximize the information obtained from each experiment and to quantify performance of devices and were experimentally validated using the SlipChip platform. MV digital PCR was demonstrated to perform reliably, and results from wells of different volumes agreed with one another. No artifacts due to different surface-to-volume ratios were observed, and single molecule amplification in volumes ranging from 1 to 125 nL was self-consistent. The device presented here was designed to meet the testing requirements for measuring clinically relevant levels of HIV viral load at the point-of-care (in plasma, <500 molecules/mL to >1,000,000 molecules/mL), and the predicted resolution and dynamic range was experimentally validated using a control sequence of DNA. This approach simplifies digital PCR experiments, saves space, and thus enables multiplexing using separate areas for each sample on one chip, and facilitates the development of new high-performance diagnostic tools for resource-limited applications. The theory and software presented here are general and are applicable to designing and analyzing other digital analytical platforms including digital immunoassays and digital bacterial analysis. It is not limited to SlipChip and could also be useful for the design of systems on platforms including valve-based and droplet-based platforms. In a separate publication by Shen et al. (J. Am. Chem. Soc., 2011, DOI: 10.1021/ja2060116), this approach is used to design and test digital RT-PCR devices for quantifying RNA.

Flight Dynamic Simulation of Fighter In the Asymmetric External Store Release Process

NASA Astrophysics Data System (ADS)

Safi’i, Imam; Arifianto, Ony; Nurohman, Chandra

2018-04-01

In the fighter design, it is important to evaluate and analyze the flight dynamic of the aircraft earlier in the development process. One of the case is the dynamics of external store release process. A simulation tool can be used to analyze the fighter/external store system’s dynamics in the preliminary design stage. This paper reports the flight dynamics of Jet Fighter Experiment (JF-1 E) in asymmetric Advance Medium Range Air to Air Missile (AMRAAM) release process through simulations. The JF-1 E and AIM 120 AMRAAAM models are built by using Advanced Aircraft Analysis (AAA) and Missile Datcom software. By using these softwares, the aerodynamic stability and control derivatives can be obtained and used to model the dynamic characteristic of the fighter and the external store. The dynamic system is modeled by using MATLAB/Simulink software. By using this software, both the fighter/external store integration and the external store release process is simulated, and the dynamic of the system can be analyzed.

Developing a workstation-based, real-time simulation for rapid handling qualities evaluations during design

NASA Technical Reports Server (NTRS)

Anderson, Frederick; Biezad, Daniel J.

1994-01-01

This paper describes the Rapid Aircraft DynamIcs AssessmeNt (RADIAN) project - an integration of the Aircraft SYNThesis (ACSTNT) design code with the USAD DATCOM code that estimates stability derivatives. Both of these codes are available to universities. These programs are then linked to flight simulation and flight controller synthesis tools and resulting design is evaluated on a graphics workstation. The entire process reduces the preliminary design time by an order of magnitude and provides an initial handling qualities evaluation of the design coupled to a control law. The integrated design process is applicable to both conventional aircraft taken from current textbooks and to unconventional designs emphasizing agility and propulsive control of attitude. The interactive and concurrent nature of the design process has been well received by industry and by design engineers at NASA. The process is being implemented into the design curriculum and is being used by students who view it as a significant advance over prior methods.

Mass Digitization of Books

ERIC Educational Resources Information Center

Coyle, Karen

2006-01-01

Mass digitization of the bound volumes that we generally call "books" has begun, and, thanks to the interest in Google and all that it does, it is getting widespread media attention. The Open Content Alliance (OCA), a library initiative formed after Google announced its library book digitization project, has brought library digitization projects…

Digital holographic tomography based on spectral interferometry.

PubMed

Yu, Lingfeng; Chen, Zhongping

2007-10-15

A digital holographic tomography system has been developed with the use of an inexpensive broadband light source and a fiber-based spectral interferometer. Multiple synthesized holograms (or object wave fields) of different wavelengths are obtained by transversely scanning a probe beam. The acquisition speed is improved compared with conventional wavelength-scanning digital holographic systems. The optical field of a volume around the object location is calculated by numerical diffraction from each synthesized hologram, and all such field volumes are numerically superposed to create the three-dimensional tomographic image. Experiments were performed to demonstrate the idea.

Techtalk: Cloud Computing and Developmental Education

ERIC Educational Resources Information Center

Holschuh, Douglas R.; Caverly, David C.

2010-01-01

Techtalk in Volume 33 has been addressing the digital divide in technology, first through the use of mobile phones and then through the development of digital literacies with digital storytelling. This third and final column in the series looks at bridging both the hardware/software divide and the digital literacies divide through the educational…

The NASA digital VGH program. Exploration of methods and final results. Volume 1: Development of methods

NASA Technical Reports Server (NTRS)

Crabill, Norman L.

1989-01-01

Two hundred hours of Lockheed L 1011 digital flight data recorder data taken in 1973 were used to develop methods and procedures for obtaining statistical data useful for updating airliner airworthiness design criteria. Five thousand hours of additional data taken in 1978 to 1982 are reported in volumes 2, 3, 4 and 5.

Writing and Digital Media

ERIC Educational Resources Information Center

van Waes, Luuk, Ed.; Leijten, Marielle, Ed.; Neuwirth, Chris, Ed.

2006-01-01

Digital media has become an increasingly powerful force in modern society. This volume brings together outstanding European, American and Australian research in "writing and digital media" and explores its cognitive, social and cultural implications. In addition to presenting programs of original research by internationally known…

The relationships between breast volume, breast dense volume and volumetric breast density with body mass index, body fat mass and ethnicity

NASA Astrophysics Data System (ADS)

Zakariyah, N.; Pathy, N. B.; Taib, N. A. M.; Rahmat, K.; Judy, C. W.; Fadzil, F.; Lau, S.; Ng, K. H.

2016-03-01

It has been shown that breast density and obesity are related to breast cancer risk. The aim of this study is to investigate the relationships of breast volume, breast dense volume and volumetric breast density (VBD) with body mass index (BMI) and body fat mass (BFM) for the three ethnic groups (Chinese, Malay and Indian) in Malaysia. We collected raw digital mammograms from 2450 women acquired on three digital mammography systems. The mammograms were analysed using Volpara software to obtain breast volume, breast dense volume and VBD. Body weight, BMI and BFM of the women were measured using a body composition analyser. Multivariable logistic regression was used to determine the independent predictors of increased overall breast volume, breast dense volume and VBD. Indians have highest breast volume and breast dense volume followed by Malays and Chinese. While Chinese are highest in VBD, followed by Malay and Indian. Multivariable analysis showed that increasing BMI and BFM were independent predictors of increased overall breast volume and dense volume. Moreover, BMI and BFM were independently and inversely related to VBD.

Quantitative breast density analysis using tomosynthesis and comparison with MRI and digital mammography.

PubMed

Moon, Woo Kyung; Chang, Jie-Fan; Lo, Chung-Ming; Chang, Jung Min; Lee, Su Hyun; Shin, Sung Ui; Huang, Chiun-Sheng; Chang, Ruey-Feng

2018-02-01

Breast density at mammography has been used as markers of breast cancer risk. However, newly introduced tomosynthesis and computer-aided quantitative method could provide more reliable breast density evaluation. In the experiment, 98 tomosynthesis image volumes were obtained from 98 women. For each case, an automatic skin removal was used and followed by a fuzzy c-mean (FCM) classifier which separated the fibroglandular tissues from other tissues in breast area. Finally, percent of breast density and breast volume were calculated and the results were compared with MRI. In addition, the percent of breast density and breast area of digital mammography calculated using the software Cumulus (University of Toronto, Toronto, ON, Canada.) were also compared with 3-D modalities. Percent of breast density and breast volume, which were computed from tomosynthesis, MRI and digital mammography were 17.37% ± 4.39% and 607.12 cm 3  ± 323.01 cm 3 , 20.3% ± 8.6% and 537.59 cm 3  ± 287.74 cm 3 , and 12.03% ± 4.08%, respectively. There were significant correlations on breast density as well as volume between tomosynthesis and MRI (R = 0.482 and R = 0.805), tomosynthesis and breast density with breast area of digital mammography (R = 0.789 and R = 0.877), and MRI and breast density with breast area of digital mammography (R = 0.482 and R = 0.857) (all P values < .001). Breast density and breast volume evaluated from tomosynthesis, MRI and breast density and breast area of digital mammographic images have significant correlations and indicate that tomosynthesis could provide useful 3-D information on breast density through proposed method. Copyright © 2017 Elsevier B.V. All rights reserved.

Use of Digital Volume Correlation to Measure Deformation of Shale Using Natural Markers

NASA Astrophysics Data System (ADS)

Dewers, T. A.; Quintana, E.; Ingraham, M. D.; Jacques, C. L.

2016-12-01

We apply digital volume correlation (DVC) to interpreting deformation as influenced by shale heterogeneity. An extension of digital image correlation, DVC uses 3D images (CT Scans) of a sample before, during and after loading to determine deformation in terms of a 3D strain map. The technology tracks the deformation of high and low density regions within the sample to determine full field 3D strains within the sample. High pyrite shales (Woodford and Marcellus in this study) are being used as the high density pyrite serves as an excellent point to track in the volume correlation. Preliminary results indicate that this technology is promising for measuring true volume strains, strain localization, and strain portioning by microlithofacies within specimens during testing. Sandia National Laboratories is a multi-program laboratory managed and operated by Sandia Corporation, a wholly owned subsidiary of Lockheed Martin Corporation, for the U.S. Department of Energy's National Nuclear Security Administration under contract DE-AC04-94AL85000.

Does the usage of digital chest drainage systems reduce pleural inflammation and volume of pleural effusion following oncologic pulmonary resection?-A prospective randomized trial.

PubMed

De Waele, Michèle; Agzarian, John; Hanna, Waël C; Schieman, Colin; Finley, Christian J; Macri, Joseph; Schneider, Laura; Schnurr, Terri; Farrokhyar, Forough; Radford, Katherine; Nair, Parameswaran; Shargall, Yaron

2017-06-01

Prolonged air leak and high-volume pleural drainage are the most common causes for delays in chest tube removal following lung resection. While digital pleural drainage systems have been successfully used in the management of post-operative air leak, their effect on pleural drainage and inflammation has not been studied before. We hypothesized that digital drainage systems (as compared to traditional analog continuous suction), using intermittent balanced suction, are associated with decreased pleural inflammation and postoperative drainage volumes, thus leading to earlier chest tube removal. One hundred and three [103] patients were enrolled and randomized to either analog (n=50) or digital (n=53) drainage systems following oncologic lung resection. Chest tubes were removed according to standardized, pre-defined protocol. Inflammatory mediators [interleukin-1B (IL-1B), 6, 8, tumour necrosis factor-alpha (TNF-α)] in pleural fluid and serum were measured and analysed. The primary outcome of interest was the difference in total volume of postoperative fluid drainage. Secondary outcome measures included duration of chest tube in-situ, prolonged air-leak incidence, length of hospital stay and the correlation between pleural effusion formation, degree of inflammation and type of drainage system used. There was no significant difference in total amount of fluid drained or length of hospital stay between the two groups. A trend for shorter chest tube duration was found with the digital system when compared to the analog (P=0.055). Comparison of inflammatory mediator levels revealed no significant differences between digital and analog drainage systems. The incidence of prolonged post-operative air leak was significantly higher when using the analog system (9 versus 2 patients; P=0.025). Lobectomy was associated with longer chest tube duration (P=0.001) and increased fluid drainage when compared to sub-lobar resection (P<0.001), regardless of drainage system. Use of post-lung resection digital drainage does not appear to decrease pleural fluid formation, but is associated with decreased prolonged air leaks. Total pleural effusion volumes did not differ with the type of drainage system used. These findings support previously established benefits of the digital system in decreasing prolonged air leaks, but the advantages do not appear to extend to decreased pleural fluid formation.

Rapid, low-cost photogrammetry to monitor volcanic eruptions: an example from Mount St. Helens, Washington, USA

USGS Publications Warehouse

Diefenbach, Angela K.; Crider, Juliet G.; Schilling, Steve P.; Dzurisin, Daniel

2012-01-01

We describe a low-cost application of digital photogrammetry using commercially available photogrammetric software and oblique photographs taken with an off-the-shelf digital camera to create sequential digital elevation models (DEMs) of a lava dome that grew during the 2004–2008 eruption of Mount St. Helens (MSH) volcano. Renewed activity at MSH provided an opportunity to devise and test this method, because it could be validated against other observations of this well-monitored volcano. The datasets consist of oblique aerial photographs (snapshots) taken from a helicopter using a digital single-lens reflex camera. Twelve sets of overlapping digital images of the dome taken during 2004–2007 were used to produce DEMs and to calculate lava dome volumes and extrusion rates. Analyses of the digital images were carried out using photogrammetric software to produce three-dimensional coordinates of points identified in multiple photos. The evolving morphology of the dome was modeled by comparing successive DEMs. Results were validated by comparison to volume measurements derived from traditional vertical photogrammetric surveys by the US Geological Survey Cascades Volcano Observatory. Our technique was significantly less expensive and required less time than traditional vertical photogrammetric techniques; yet, it consistently yielded volume estimates within 5% of the traditional method. This technique provides an inexpensive, rapid assessment tool for tracking lava dome growth or other topographic changes at restless volcanoes.

CD-ROM publication of the Mars digital cartographic data base

NASA Technical Reports Server (NTRS)

Batson, R. M.; Eliason, E. M.; Soderblom, L. A.; Edwards, Kathleen; Wu, Sherman S. C.

1991-01-01

The recently completed Mars mosaicked digital image model (MDIM) and the soon-to-be-completed Mars digital terrain model (DTM) are being transcribed to optical disks to simplify distribution to planetary investigators. These models, completed in FY 1991, provide a cartographic base to which all existing Mars data can be registered. The digital image map of Mars is a cartographic extension of a set of compact disk read-only memory (CD-ROM) volumes containing individual Viking Orbiter images now being released. The data in these volumes are pristine in the sense that they were processed only to the extent required to view them as images. They contain the artifacts and the radiometric, geometric, and photometric characteristics of the raw data transmitted by the spacecraft. This new set of volumes, on the other hand, contains cartographic compilations made by processing the raw images to reduce radiometric and geometric distortions and to form geodetically controlled MDIM's. It also contains digitized versions of an airbrushed map of Mars as well as a listing of all feature names approved by the International Astronomical Union. In addition, special geodetic and photogrammetric processing has been performed to derive rasters of topographic data, or DTM's. The latter have a format similar to that of MDIM, except that elevation values are used in the array instead of image brightness values. The set consists of seven volumes: (1) Vastitas Borealis Region of Mars; (2) Xanthe Terra of Mars; (3) Amazonis Planitia Region of Mars; (4) Elysium Planitia Region of Mars; (5) Arabia Terra of Mars; (6) Planum Australe Region of Mars; and (7) a digital topographic map of Mars.

Digital Communications Terminal High Order Programming Language Study (DCT HOL Study). Volume I.

DTIC Science & Technology

1980-11-26

3-3 PASCAL/M Digital Marketing ......... 3-3 PASCAL/MT MT MicroSystems .................... 3-3 PASCAL/Z Ithaca IntersysteMs...II Avocet Systems, Inc. 3.6 PASCAL - ISO PASCAL Whitesmith, Ltd. - PASCAL 64000 lbwlett-Packard - PASCAL/H Digital Marketing - PASCAL/MT MT

Mapping debris-flow hazard in Honolulu using a DEM

USGS Publications Warehouse

Ellen, Stephen D.; Mark, Robert K.; ,

1993-01-01

A method for mapping hazard posed by debris flows has been developed and applied to an area near Honolulu, Hawaii. The method uses studies of past debris flows to characterize sites of initiation, volume at initiation, and volume-change behavior during flow. Digital simulations of debris flows based on these characteristics are then routed through a digital elevation model (DEM) to estimate degree of hazard over the area.

High-resolution Episcopic Microscopy (HREM) - Simple and Robust Protocols for Processing and Visualizing Organic Materials

PubMed Central

Geyer, Stefan H.; Maurer-Gesek, Barbara; Reissig, Lukas F.; Weninger, Wolfgang J.

2017-01-01

We provide simple protocols for generating digital volume data with the high-resolution episcopic microscopy (HREM) method. HREM is capable of imaging organic materials with volumes up to 5 x 5 x 7 mm3 in typical numeric resolutions between 1 x 1 x 1 and 5 x 5 x 5 µm3. Specimens are embedded in methacrylate resin and sectioned on a microtome. After each section an image of the block surface is captured with a digital video camera that sits on the phototube connected to the compound microscope head. The optical axis passes through a green fluorescent protein (GFP) filter cube and is aligned with a position, at which the bock holder arm comes to rest after each section. In this way, a series of inherently aligned digital images, displaying subsequent block surfaces are produced. Loading such an image series in three-dimensional (3D) visualization software facilitates the immediate conversion to digital volume data, which permit virtual sectioning in various orthogonal and oblique planes and the creation of volume and surface rendered computer models. We present three simple, tissue specific protocols for processing various groups of organic specimens, including mouse, chick, quail, frog and zebra fish embryos, human biopsy material, uncoated paper and skin replacement material. PMID:28715372

High-resolution Episcopic Microscopy (HREM) - Simple and Robust Protocols for Processing and Visualizing Organic Materials.

PubMed

Geyer, Stefan H; Maurer-Gesek, Barbara; Reissig, Lukas F; Weninger, Wolfgang J

2017-07-07

We provide simple protocols for generating digital volume data with the high-resolution episcopic microscopy (HREM) method. HREM is capable of imaging organic materials with volumes up to 5 x 5 x 7 mm 3 in typical numeric resolutions between 1 x 1 x 1 and 5 x 5 x 5 µm 3 . Specimens are embedded in methacrylate resin and sectioned on a microtome. After each section an image of the block surface is captured with a digital video camera that sits on the phototube connected to the compound microscope head. The optical axis passes through a green fluorescent protein (GFP) filter cube and is aligned with a position, at which the bock holder arm comes to rest after each section. In this way, a series of inherently aligned digital images, displaying subsequent block surfaces are produced. Loading such an image series in three-dimensional (3D) visualization software facilitates the immediate conversion to digital volume data, which permit virtual sectioning in various orthogonal and oblique planes and the creation of volume and surface rendered computer models. We present three simple, tissue specific protocols for processing various groups of organic specimens, including mouse, chick, quail, frog and zebra fish embryos, human biopsy material, uncoated paper and skin replacement material.

Digital LAMP in a sample self-digitization (SD) chip

PubMed Central

Herrick, Alison M.; Dimov, Ivan K.; Lee, Luke P.; Chiu, Daniel T.

2012-01-01

This paper describes the realization of digital loop-mediated DNA amplification (dLAMP) in a sample self-digitization (SD) chip. Digital DNA amplification has become an attractive technique to quantify absolute concentrations of DNA in a sample. While digital polymerase chain reaction is still the most widespread implementation, its use in resource—limited settings is impeded by the need for thermal cycling and robust temperature control. In such situations, isothermal protocols that can amplify DNA or RNA without thermal cycling are of great interest. Here, we showed the successful amplification of single DNA molecules in a stationary droplet array using isothermal digital loop-mediated DNA amplification. Unlike most (if not all) existing methods for sample discretization, our design allows for automated, loss-less digitization of sample volumes on-chip. We demonstrated accurate quantification of relative and absolute DNA concentrations with sample volumes of less than 2 μl. We assessed the homogeneity of droplet size during sample self-digitization in our device, and verified that the size variation was small enough such that straightforward counting of LAMP-active droplets sufficed for data analysis. We anticipate that the simplicity and robustness of our SD chip make it attractive as an inexpensive and easy-to-operate device for DNA amplification, for example in point-of-care settings. PMID:22399016

A computer system for analysis and transmission of spirometry waveforms using volume sampling.

PubMed

Ostler, D V; Gardner, R M; Crapo, R O

1984-06-01

A microprocessor-controlled data gathering system for telemetry and analysis of spirometry waveforms was implemented using a completely digital design. Spirometry waveforms were obtained from an optical shaft encoder attached to a rolling seal spirometer. Time intervals between 10-ml volume changes (volume sampling) were stored. The digital design eliminated problems of analog signal sampling. The system measured flows up to 12 liters/sec with 5% accuracy and volumes up to 10 liters with 1% accuracy. Transmission of 10 waveforms took about 3 min. Error detection assured that no data were lost or distorted during transmission. A pulmonary physician at the central hospital reviewed the volume-time and flow-volume waveforms and interpretations generated by the central computer before forwarding the results and consulting with the rural physician. This system is suitable for use in a major hospital, rural hospital, or small clinic because of the system's simplicity and small size.

Tracking a Head-Mounted Display in a Room-Sized Environment with Head-Mounted Cameras

DTIC Science & Technology

1990-04-01

poor resolution and a very limited working volume [Wan90]. 4 OPTOTRAK [Nor88] uses one camera with two dual-axis CCD infrared position sensors. Each...Nor88] Northern Digital. Trade literature on Optotrak - Northern Digital’s Three Dimensional Optical Motion Tracking and Analysis System. Northern Digital

Straight A's: Public Education Policy and Progress. Volume 12, Number 16

ERIC Educational Resources Information Center

Amos, Jason, Ed.

2012-01-01

"Straight A's: Public Education Policy and Progress" is a biweekly newsletter that focuses on education news and events both in Washington, DC and around the country. The following articles are included in this issue: (1) Digital Learning Meets Digital Democracy: Alliance for Excellent Education Accepting Public Feedback on New Digital Learning…

Estimation des masses, des centres de gravite ainsi que des moments d'inertie de l'avion cessna citation X

NASA Astrophysics Data System (ADS)

Chahbani, Samia

The masses, centers of gravity and moments of inertia are the main parameters in the three phases of the design of the aircraft. They are of extreme importance in the studies of the stability and proper functioning of the aircraft by modeling and simulation methods. Unfortunately, these data are not always available given the confidentiality of aerospace field. A question arises naturally: How to estimate the mass, center of gravity and moments of inertia of an aircraft based on only its geometry? In this context in which this thesis is realized, the masses are estimated by Raymer`s methods. The aircraft described in procedures based on mechanical techniques engineers are used for determining the centers of gravity. The DATCOM is applied for obtaining moments of inertia. Finally, the results obtained are validated by using the flight simulator at the LARCASE corresponding to Cessna Citation X. we conclude with a representation of an analytical model that sum up the different step to follow up for estimating masses, centers of gravity and moments of inertia for any commercial aircraft.

Digital tissue and what it may reveal about the brain.

PubMed

Morgan, Josh L; Lichtman, Jeff W

2017-10-30

Imaging as a means of scientific data storage has evolved rapidly over the past century from hand drawings, to photography, to digital images. Only recently can sufficiently large datasets be acquired, stored, and processed such that tissue digitization can actually reveal more than direct observation of tissue. One field where this transformation is occurring is connectomics: the mapping of neural connections in large volumes of digitized brain tissue.

Low-Cost Photogrammetric Technique Used to Measure Dome Growth at Mount St. Helens Volcano, 2007-2007

NASA Astrophysics Data System (ADS)

Diefenbach, A. K.; Crider, J. G.; Schilling, S. P.; Dzurisin, D.

2007-12-01

We describe a low-cost application of digital photogrammetry using commercial grade software, an off-the-shelf digital camera, a laptop computer and oblique photographs to reconstruct volcanic dome morphology during the on-going eruption at Mount St. Helens, Washington. Renewed activity at Mount St. Helens provides a rare opportunity to devise and test new methods for better understanding and predicting volcanic events, because the new method can be validated against other observations on this well-instrumented volcano. Uncalibrated, oblique aerial photographs (snap shots) taken from a helicopter are the raw data. Twelve sets of overlapping digital images of the dome taken during 2004-2007 were used to produce digital elevation models (DEMs) from which dome height, eruption volume and extrusion rate can be derived. Analyses of the digital images were carried out using PhotoModeler software, which produces three dimensional coordinates of points identified in multiple photos. The steps involved include: (1) calibrating the digital camera using this software package, (2) establishing control points derived from existing DEMs, (3) identifying tie points located in each photo of any given model date, and (4) identifying points in pairs of photos to build a three dimensional model of the evolving dome at each photo date. Text files of three-dimensional points encompassing the dome at each date were imported into ArcGIS and three-dimensional models (triangulated irregular network or TINs) were generated. TINs were then converted to 2 m raster DEMs. The evolving morphology of the growing dome was modeled by comparison of successive DEMs. The volume of extruded lava visible in each DEM was calculated using the 1986 pre-eruption crater floor topography as a basal surface. Results were validated by comparing volume measurements derived from traditional aerophotogrammetric surveys run by the USGS Cascades Volcano Observatory. Our new "quick and cheap" technique yields estimates of eruptive volume consistently within 5% of the volumes estimated with traditional surveys. The end result of this project is a new technique that provides an inexpensive, rapid assessment tool for tracking lava dome growth or other topographic changes at restless volcanoes.

3D volumetric modeling of grapevine biomass using Tripod LiDAR

USGS Publications Warehouse

Keightley, K.E.; Bawden, G.W.

2010-01-01

Tripod mounted laser scanning provides the means to generate high-resolution volumetric measures of vegetation structure and perennial woody tissue for the calculation of standing biomass in agronomic and natural ecosystems. Other than costly destructive harvest methods, no technique exists to rapidly and accurately measure above-ground perennial tissue for woody plants such as Vitis vinifera (common grape vine). Data collected from grapevine trunks and cordons were used to study the accuracy of wood volume derived from laser scanning as compared with volume derived from analog measurements. A set of 10 laser scan datasets were collected for each of 36 vines from which volume was calculated using combinations of two, three, four, six and 10 scans. Likewise, analog volume measurements were made by submerging the vine trunks and cordons in water and capturing the displaced water. A regression analysis examined the relationship between digital and non-digital techniques among the 36 vines and found that the standard error drops rapidly as additional scans are added to the volume calculation process and stabilizes at the four-view geometry with an average Pearson's product moment correlation coefficient of 0.93. Estimates of digital volumes are systematically greater than those of analog volumes and can be explained by the manner in which each technique interacts with the vine tissue. This laser scanning technique yields a highly linear relationship between vine volume and tissue mass revealing a new, rapid and non-destructive method to remotely measure standing biomass. This application shows promise for use in other ecosystems such as orchards and forests. ?? 2010 Elsevier B.V.

Improving and Assessing Student Hands-On Laboratory Skills through Digital Badging

ERIC Educational Resources Information Center

Hensiek, Sarah; DeKorver, Brittland K.; Harwood, Cynthia J.; Fish, Jason; O'Shea, Kevin; Towns, Marcy

2016-01-01

Building on previous success with a digital pipet badge, an evidence-centered design approach was used to develop new digital badges for measuring the volume of liquids with a buret and making a solution in a volumetric flask. These badges were implemented and assessed in two general chemistry courses. To earn the badges, students created videos…

English Teaching and New Literacies Pedagogy: Interpreting and Authoring Digital Multimedia Narratives. New Literacies and Digital Epistemologies. Volume 61

ERIC Educational Resources Information Center

Unsworth, Len, Ed.; Thomas, Angela, Ed.

2014-01-01

"English Teaching and New Literacies Pedagogy: Interpreting and Authoring Digital Multimedia Narratives" is about the fusion of media and narrative, and explores theoretical and practical dimensions of young people's engagement with contemporary forms of text. It showcases a range of critical interpretative approaches for integrating…

Real-time volume rendering of digital medical images on an iOS device

NASA Astrophysics Data System (ADS)

Noon, Christian; Holub, Joseph; Winer, Eliot

2013-03-01

Performing high quality 3D visualizations on mobile devices, while tantalizingly close in many areas, is still a quite difficult task. This is especially true for 3D volume rendering of digital medical images. Allowing this would empower medical personnel a powerful tool to diagnose and treat patients and train the next generation of physicians. This research focuses on performing real time volume rendering of digital medical images on iOS devices using custom developed GPU shaders for orthogonal texture slicing. An interactive volume renderer was designed and developed with several new features including dynamic modification of render resolutions, an incremental render loop, a shader-based clipping algorithm to support OpenGL ES 2.0, and an internal backface culling algorithm for properly sorting rendered geometry with alpha blending. The application was developed using several application programming interfaces (APIs) such as OpenSceneGraph (OSG) as the primary graphics renderer coupled with iOS Cocoa Touch for user interaction, and DCMTK for DICOM I/O. The developed application rendered volume datasets over 450 slices up to 50-60 frames per second, depending on the specific model of the iOS device. All rendering is done locally on the device so no Internet connection is required.

YF-12 cooperative airframe/propulsion control system program, volume 1

NASA Technical Reports Server (NTRS)

Anderson, D. L.; Connolly, G. F.; Mauro, F. M.; Reukauf, P. J.; Marks, R. (Editor)

1980-01-01

Several YF-12C airplane analog control systems were converted to a digital system. Included were the air data computer, autopilot, inlet control system, and autothrottle systems. This conversion was performed to allow assessment of digital technology applications to supersonic cruise aircraft. The digital system was composed of a digital computer and specialized interface unit. A large scale mathematical simulation of the airplane was used for integration testing and software checkout.

From Hahnemann's hand to your computer screen: building a digital homeopathy collection

PubMed Central

Mix, Lisa A; Cameron, Kathleen

2011-01-01

The University of California, San Francisco (UCSF), Library holds the unique manuscript of the sixth edition of Samuel Hahnemann's Organon der Heilkunst, the primary text of homeopathy. The manuscript volume is Hahnemann's own copy of the fifth edition of the Organon with his notes for the sixth edition, handwritten throughout the volume. There is a high level of interest in the Organon manuscript, particularly among homeopaths. This led to the decision to present a digital surrogate on the web to make it accessible to a wider audience. Digitizing Hahnemann's manuscript and determining the best method of presentation on the web posed several challenges. Lessons learned in the course of this project will inform future digital projects. This article discusses the historical significance of the sixth edition of Hahnemann's Organon, its context in UCSF's homeopathy collections, and the specifics of developing the online homeopathy collection. PMID:21243055

3D-information fusion from very high resolution satellite sensors

NASA Astrophysics Data System (ADS)

Krauss, T.; d'Angelo, P.; Kuschk, G.; Tian, J.; Partovi, T.

2015-04-01

In this paper we show the pre-processing and potential for environmental applications of very high resolution (VHR) satellite stereo imagery like these from WorldView-2 or Pl'eiades with ground sampling distances (GSD) of half a metre to a metre. To process such data first a dense digital surface model (DSM) has to be generated. Afterwards from this a digital terrain model (DTM) representing the ground and a so called normalized digital elevation model (nDEM) representing off-ground objects are derived. Combining these elevation based data with a spectral classification allows detection and extraction of objects from the satellite scenes. Beside the object extraction also the DSM and DTM can directly be used for simulation and monitoring of environmental issues. Examples are the simulation of floodings, building-volume and people estimation, simulation of noise from roads, wave-propagation for cellphones, wind and light for estimating renewable energy sources, 3D change detection, earthquake preparedness and crisis relief, urban development and sprawl of informal settlements and much more. Also outside of urban areas volume information brings literally a new dimension to earth oberservation tasks like the volume estimations of forests and illegal logging, volume of (illegal) open pit mining activities, estimation of flooding or tsunami risks, dike planning, etc. In this paper we present the preprocessing from the original level-1 satellite data to digital surface models (DSMs), corresponding VHR ortho images and derived digital terrain models (DTMs). From these components we present how a monitoring and decision fusion based 3D change detection can be realized by using different acquisitions. The results are analyzed and assessed to derive quality parameters for the presented method. Finally the usability of 3D information fusion from VHR satellite imagery is discussed and evaluated.

A flexible, open, decentralized system for digital pathology networks.

PubMed

Schuler, Robert; Smith, David E; Kumaraguruparan, Gowri; Chervenak, Ann; Lewis, Anne D; Hyde, Dallas M; Kesselman, Carl

2012-01-01

High-resolution digital imaging is enabling digital archiving and sharing of digitized microscopy slides and new methods for digital pathology. Collaborative research centers, outsourced medical services, and multi-site organizations stand to benefit from sharing pathology data in a digital pathology network. Yet significant technological challenges remain due to the large size and volume of digitized whole slide images. While information systems do exist for managing local pathology laboratories, they tend to be oriented toward narrow clinical use cases or offer closed ecosystems around proprietary formats. Few solutions exist for networking digital pathology operations. Here we present a system architecture and implementation of a digital pathology network and share results from a production system that federates major research centers.

A Flexible, Open, Decentralized System for Digital Pathology Networks

PubMed Central

SMITH, David E.; KUMARAGURUPARAN, Gowri; CHERVENAK, Ann; LEWIS, Anne D.; HYDE, Dallas M.; KESSELMAN, Carl

2014-01-01

High-resolution digital imaging is enabling digital archiving and sharing of digitized microscopy slides and new methods for digital pathology. Collaborative research centers, outsourced medical services, and multi-site organizations stand to benefit from sharing pathology data in a digital pathology network. Yet significant technological challenges remain due to the large size and volume of digitized whole slide images. While information systems do exist for managing local pathology laboratories, they tend to be oriented toward narrow clinical use cases or offer closed ecosystems around proprietary formats. Few solutions exist for networking digital pathology operations. Here we present a system architecture and implementation of a digital pathology network and share results from a production system that federates major research centers. PMID:22941985

The validity of ultrasound estimation of muscle volumes.

PubMed

Infantolino, Benjamin W; Gales, Daniel J; Winter, Samantha L; Challis, John H

2007-08-01

The purpose of this study was to validate ultrasound muscle volume estimation in vivo. To examine validity, vastus lateralis ultrasound images were collected from cadavers before muscle dissection; after dissection, the volumes were determined by hydrostatic weighing. Seven thighs from cadaver specimens were scanned using a 7.5-MHz ultrasound probe (SSD-1000, Aloka, Japan). The perimeter of the vastus lateralis was identified in the ultrasound images and manually digitized. Volumes were then estimated using the Cavalieri principle, by measuring the image areas of sets of parallel two-dimensional slices through the muscles. The muscles were then dissected from the cadavers, and muscle volume was determined via hydrostatic weighing. There was no statistically significant difference between the ultrasound estimation of muscle volume and that estimated using hydrostatic weighing (p > 0.05). The mean percentage error between the two volume estimates was 0.4% +/- 6.9. Three operators all performed four digitizations of all images from one randomly selected muscle; there was no statistical difference between operators or trials and the intraclass correlation was high (>0.8). The results of this study indicate that ultrasound is an accurate method for estimating muscle volumes in vivo.

Northeast Artificial Intelligence Consortium (NAIC) Review of Technical Tasks. Volume 2, Part 1.

DTIC Science & Technology

1987-07-01

34- . 6.2 Transformation Invariant Attributes for S Digitized Object Outlines ................................. 469 6.3 Design of an Inference Engine for an...Attributes for Digital Object Outlines ...................................... 597 7 SPEECH UNDERSTANDING RESEARCH ( Rochester Institute of Technology...versatile maintenance expert system ES) for trouble-shooting--’ digital circuits. +" Some diagnosis systems, such as MYCLN [19] for medical diagnosis and CRIB

Imaging and computational considerations for image computed permeability: Operating envelope of Digital Rock Physics

NASA Astrophysics Data System (ADS)

Saxena, Nishank; Hows, Amie; Hofmann, Ronny; Alpak, Faruk O.; Freeman, Justin; Hunter, Sander; Appel, Matthias

2018-06-01

This study defines the optimal operating envelope of the Digital Rock technology from the perspective of imaging and numerical simulations of transport properties. Imaging larger volumes of rocks for Digital Rock Physics (DRP) analysis improves the chances of achieving a Representative Elementary Volume (REV) at which flow-based simulations (1) do not vary with change in rock volume, and (2) is insensitive to the choice of boundary conditions. However, this often comes at the expense of image resolution. This trade-off exists due to the finiteness of current state-of-the-art imaging detectors. Imaging and analyzing digital rocks that sample the REV and still sufficiently resolve pore throats is critical to ensure simulation quality and robustness of rock property trends for further analysis. We find that at least 10 voxels are needed to sufficiently resolve pore throats for single phase fluid flow simulations. If this condition is not met, additional analyses and corrections may allow for meaningful comparisons between simulation results and laboratory measurements of permeability, but some cases may fall outside the current technical feasibility of DRP. On the other hand, we find that the ratio of field of view and effective grain size provides a reliable measure of the REV for siliciclastic rocks. If this ratio is greater than 5, the coefficient of variation for single-phase permeability simulations drops below 15%. These imaging considerations are crucial when comparing digitally computed rock flow properties with those measured in the laboratory. We find that the current imaging methods are sufficient to achieve both REV (with respect to numerical boundary conditions) and required image resolution to perform digital core analysis for coarse to fine-grained sandstones.

Evaluation of usefulness of Skylab EREP S-190 and S-192 imagery in multistage forest surveys

NASA Technical Reports Server (NTRS)

Langley, P. G. (Principal Investigator)

1973-01-01

The author has identified the following significant results. A unique digital timber volume estimation system with digital data for two ERTS-1 MSS bands was tested. The system was tested on a 64-square mile area in Northern California's Trinity Alps. The outcome of a systematic experiment in which possible combinations of the two bands (MSS 5 and 7) were tried, showed than an estimated gain in precision of 50% can be obtained in a multistage sampling design. Especially the difference between the two bands proved to be of major importance for the estimation of biomass in the form of timber volume. Identical tests as the one performed will be conducted with various S-192 bands when the digital data become available.

Information management advanced development. Volume 3: Digital data bus breadboard

NASA Technical Reports Server (NTRS)

Gerber, C. R.

1972-01-01

The design, development, and evaluation of the digital data bus breadboard for the modular space station are discussed. Subjects presented are: (1) requirements summary, (2) parametric data for bus design, (3) redundancy concepts, and (4) data bus breadboard performance and interface requirements.

Image data processing system requirements study. Volume 1: Analysis. [for Earth Resources Survey Program

NASA Technical Reports Server (NTRS)

Honikman, T.; Mcmahon, E.; Miller, E.; Pietrzak, L.; Yorsz, W.

1973-01-01

Digital image processing, image recorders, high-density digital data recorders, and data system element processing for use in an Earth Resources Survey image data processing system are studied. Loading to various ERS systems is also estimated by simulation.

Ground-Level Digital Terrain Model (DTM) Construction from Tandem-X InSAR Data and Worldview Stereo-Photogrammetric Images

NASA Technical Reports Server (NTRS)

Lee, Seung-Kuk; Fatoyinbo, Temilola; Lagomasino, David; Osmanoglu, Batuhan; Feliciano, Emanuelle

2016-01-01

The ground-level digital elevation model (DEM) or digital terrain model (DTM) information are invaluable for environmental modeling, such as water dynamics in forests, canopy height, forest biomass, carbon estimation, etc. We propose to extract the DTM over forested areas from the combination of interferometric complex coherence from single-pass TanDEM-X (TDX) data at HH polarization and Digital Surface Model (DSM) derived from high-resolution WorldView (WV) image pair by means of random volume over ground (RVoG) model. The RVoG model is a widely and successfully used model for polarimetric SAR interferometry (Pol-InSAR) technique for vertical forest structure parameter retrieval [1][2][3][4]. The ground-level DEM have been obtained by complex volume decorrelation in the RVoG model with the DSM using stereo-photogrammetric technique. Finally, the airborne lidar data were used to validate the ground-level DEM and forest canopy height results.

Naval Postgraduate School Research. Volume 9, Number 1, February 1999

DTIC Science & Technology

1999-02-01

before the digitization, since these add noise and nonlinear distortion to the signal. After digitization by the digital antenna, the data stream can be...instructions, searching existing data sources, gathering and maintaining the data needed, and completing and reviewing the collection of information...like pulse compression. (Gener- ally, few experiments have measured the jitter of the lasers.) From the data , we note that the pulse width require

Digital Systems Validation Handbook. Volume 2. Chapter 18. Avionic Data Bus Integration Technology

DTIC Science & Technology

1993-11-01

interaction between a digital data bus and an avionic system. Very Large Scale Integration (VLSI) ICs and multiversion software, which make up digital...1984, the Sperry Corporation developed a fault tolerant system which employed multiversion programming, voting, and monitoring for error detection and...formulate all the significant behavior of a system. MULTIVERSION PROGRAMMING. N-version programming. N-VERSION PROGRAMMING. The independent coding of a

Signal-to-noise ratio estimation in digital computer simulation of lowpass and bandpass systems with applications to analog and digital communications, volume 3

NASA Technical Reports Server (NTRS)

Tranter, W. H.; Turner, M. D.

1977-01-01

Techniques are developed to estimate power gain, delay, signal-to-noise ratio, and mean square error in digital computer simulations of lowpass and bandpass systems. The techniques are applied to analog and digital communications. The signal-to-noise ratio estimates are shown to be maximum likelihood estimates in additive white Gaussian noise. The methods are seen to be especially useful for digital communication systems where the mapping from the signal-to-noise ratio to the error probability can be obtained. Simulation results show the techniques developed to be accurate and quite versatile in evaluating the performance of many systems through digital computer simulation.

Combined Synchrotron X-ray Diffraction and Digital Image Correlation Technique for Measurement of Austenite Transformation with Strain in TRIP-assisted Steels

DOE Office of Scientific and Technical Information (OSTI.GOV)

Poling, Whitney A.; Savic, Vesna; Hector, Louis G.

2016-04-05

The strain-induced, diffusionless shear transformation of retained austenite to martensite during straining of transformation induced plasticity (TRIP) assisted steels increases strain hardening and delays necking and fracture leading to exceptional ductility and strength, which are attractive for automotive applications. A novel technique that provides the retained austenite volume fraction variation with strain in TRIP-assisted steels with improved precision is presented. Digital images of the gauge section of tensile specimens were first recorded up to selected plastic strains with a stereo digital image correlation (DIC) system. The austenite volume fraction was measured by synchrotron X-ray diffraction from small squares cut frommore » the gage section. Strain fields in the squares were then computed by localizing the strain measurement to the corresponding region of a given square during DIC post-processing of the images recorded during tensile testing. Results obtained for a QP980 steel are used to study the influence of initial volume fraction of austenite and the austenite transformation with strain on tensile mechanical behavior.« less

Digital Correction of Motion Artifacts in Microscopy Image Sequences Collected from Living Animals Using Rigid and Non-Rigid Registration

PubMed Central

Lorenz, Kevin S.; Salama, Paul; Dunn, Kenneth W.; Delp, Edward J.

2013-01-01

Digital image analysis is a fundamental component of quantitative microscopy. However, intravital microscopy presents many challenges for digital image analysis. In general, microscopy volumes are inherently anisotropic, suffer from decreasing contrast with tissue depth, lack object edge detail, and characteristically have low signal levels. Intravital microscopy introduces the additional problem of motion artifacts, resulting from respiratory motion and heartbeat from specimens imaged in vivo. This paper describes an image registration technique for use with sequences of intravital microscopy images collected in time-series or in 3D volumes. Our registration method involves both rigid and non-rigid components. The rigid registration component corrects global image translations, while the non-rigid component manipulates a uniform grid of control points defined by B-splines. Each control point is optimized by minimizing a cost function consisting of two parts: a term to define image similarity, and a term to ensure deformation grid smoothness. Experimental results indicate that this approach is promising based on the analysis of several image volumes collected from the kidney, lung, and salivary gland of living rodents. PMID:22092443

Integrating Data across Digital Activities

ERIC Educational Resources Information Center

DiCerbo, Kristen

2016-01-01

The volume of data that can be captured and stored from students' everyday interactions with digital environments allows for the creation of models of student knowledge, skills, and attributes unobtrusively. However, models and techniques for transforming these data into information that is useful for educators have not been established. This…

Digitalisierung - Management Zwischen 0 und 1

NASA Astrophysics Data System (ADS)

Friedrich, Stefan; Rachholz, Josef

2017-09-01

Digitization as a process of expressing actions and values by codes 0 and 1 has already has become part of our lives. Digitization enables enterprises to improve production, sales and to increase volume of production. However, no standard digitization strategy has been yet developed. Even in the digitized business process management system, the most important position remains to a human being. The improvement of software products, their availability and the education system in the area of introduction and use of information technology is thus a striking feature in development of managing (but also other) current processes.

Analysis of the Effects of Streamwise Lift Distribution on Sonic Boom Signature

NASA Technical Reports Server (NTRS)

Yoo, Paul

2013-01-01

Investigation of sonic boom has been one of the major areas of study in aeronautics due to the benefits a low-boom aircraft has in both civilian and military applications. This work conducts a numerical analysis of the effects of streamwise lift distribution on the shock coalescence characteristics. A simple wing-canard-stabilator body model is used in the numerical simulation. The streamwise lift distribution is varied by fixing the canard at a deflection angle while trimming the aircraft with the wing and the stabilator at the desired lift coefficient. The lift and the pitching moment coefficients are computed using the Missile DATCOM v. 707. The flow field around the wing-canard- stabilator body model is resolved using the OVERFLOW-2 flow solver. Overset/ chimera grid topology is used to simplify the grid generation of various configurations representing different streamwise lift distributions. The numerical simulations are performed without viscosity unless it is required for numerical stability. All configurations are simulated at Mach 1.4, angle-of-attack of 1.50, lift coefficient of 0.05, and pitching moment coefficient of approximately 0. Four streamwise lift distribution configurations were tested.

Storage media for computers in radiology.

PubMed

Dandu, Ravi Varma

2008-11-01

The introduction and wide acceptance of digital technology in medical imaging has resulted in an exponential increase in the amount of data produced by the radiology department. There is an insatiable need for storage space to archive this ever-growing volume of image data. Healthcare facilities should plan the type and size of the storage media that they needed, based not just on the volume of data but also on considerations such as the speed and ease of access, redundancy, security, costs, as well as the longevity of the archival technology. This article reviews the various digital storage media and compares their merits and demerits.

Guidance, Navigation and Control Digital Emulation Technology Laboratory. Volume 1. Part 3. Task 1: Digital Emulation Technology Laboratory

DTIC Science & Technology

1991-09-27

ISTT IEXIT IGO MAGV TGII ROLLERI YAWER LA !10 TRMTGO TGE 1 TGE2ALI IBURNI ACQD UVs MVS CMMD VCMD IFTAB TFTAB ACSLEV DTOFFV IVTAB TB URNM TI MONVI TVTAB...Volume 1, Part 3 C b inertdfatal loup ndxjust compu ed . Missile states must not CI C transition has occurred since the last C C integration step . The...SUBROUTINE RESP2R ( DT,WD,ZD,CILL,CIL,CI., COLL ,COL,CO) C C SUBROUTINE NAME : RESP2R C C AUTHOR(S) :D. F. SMITH C C FUNCTION Given a second

Civic Engagement through Digital Citizenship: Engaging Youth in Active, Participatory Citizenship through Digital Media. The Progress of Education Reform. Volume 13, Number 1

ERIC Educational Resources Information Center

Baumann, Paul

2012-01-01

Participatory digital media--broadly defined as media such as the Internet, social network sites and cell phones that allow users to interact--are ubiquitous among today's youth. Among teens ages 12-17, 95% have access to the Internet; 70% go online daily; 80% use social networking sites such as Facebook and Twitter; and 77% have cell phones. Many…

FIAMODEL: Users Guide Version 3.0.

Treesearch

Scott A. Pugh; David D. Reed; Kurt S. Pregitzer; Patrick D. Miles

2002-01-01

FIAMODEL is a geographic information system (GIS program used to summarize Forest Inventory and Analysis (FIA, USDA Forest Service) data such as volume. The model runs in ArcView and allows users to select FIA plots with heads-up-digitizing, overlays of digital map layers, or queries based on specific plot attributes.

The Last Book: The Delivery of Future Content.

ERIC Educational Resources Information Center

Lim, Edward

This paper discusses the future of the printed book. The first section considers factors contributing to predictions of its eventual demise and replacement by electronic versions, the increasing volume of digitized material, superior characteristics of digital publications, and the development of technologies that will allow the e-book to become…

Three-dimensional photography for the evaluation of facial profiles in obstructive sleep apnoea.

PubMed

Lin, Shih-Wei; Sutherland, Kate; Liao, Yu-Fang; Cistulli, Peter A; Chuang, Li-Pang; Chou, Yu-Ting; Chang, Chih-Hao; Lee, Chung-Shu; Li, Li-Fu; Chen, Ning-Hung

2018-06-01

Craniofacial structure is an important determinant of obstructive sleep apnoea (OSA) syndrome risk. Three-dimensional stereo-photogrammetry (3dMD) is a novel technique which allows quantification of the craniofacial profile. This study compares the facial images of OSA patients captured by 3dMD to three-dimensional computed tomography (3-D CT) and two-dimensional (2-D) digital photogrammetry. Measurements were correlated with indices of OSA severity. Thirty-eight patients diagnosed with OSA were included, and digital photogrammetry, 3dMD and 3-D CT were performed. Distances, areas, angles and volumes from the images captured by three methods were analysed. Almost all measurements captured by 3dMD showed strong agreement with 3-D CT measurements. Results from 2-D digital photogrammetry showed poor agreement with 3-D CT. Mandibular width, neck perimeter size and maxillary volume measurements correlated well with the severity of OSA using all three imaging methods. Mandibular length, facial width, binocular width, neck width, cranial base triangle area, cranial base area 1 and middle cranial fossa volume correlated well with OSA severity using 3dMD and 3-D CT, but not with 2-D digital photogrammetry. 3dMD provided accurate craniofacial measurements of OSA patients, which were highly concordant with those obtained by CT, while avoiding the radiation associated with CT. © 2018 Asian Pacific Society of Respirology.

3D tumor measurement in cone-beam CT breast imaging

NASA Astrophysics Data System (ADS)

Chen, Zikuan; Ning, Ruola

2004-05-01

Cone-beam CT breast imaging provides a digital volume representation of a breast. With a digital breast volume, the immediate task is to extract the breast tissue information, especially for suspicious tumors, preferably in an automatic manner or with minimal user interaction. This paper reports a program for three-dimensional breast tissue analysis. It consists of volumetric segmentation (by globally thresholding), subsegmentation (connection-based separation), and volumetric component measurement (volume, surface, shape, and other geometrical specifications). A combination scheme of multi-thresholding and binary volume morphology is proposed to fast determine the surface gradients, which may be interpreted as the surface evolution (outward growth or inward shrinkage) for a tumor volume. This scheme is also used to optimize the volumetric segmentation. With a binary volume, we decompose the foreground into components according to spatial connectedness. Since this decomposition procedure is performed after volumetric segmentation, it is called subsegmentation. The subsegmentation brings the convenience for component visualization and measurement, in the whole support space, without interference from others. Upon the tumor component identification, we measure the following specifications: volume, surface area, roundness, elongation, aspect, star-shapedness, and location (centroid). A 3D morphological operation is used to extract the cluster shell and, by delineating the corresponding volume from the grayscale volume, to measure the shell stiffness. This 3D tissue measurement is demonstrated with a tumor-borne breast specimen (a surgical part).

One way Doppler Extractor. Volume 2: Digital VCO technique

NASA Technical Reports Server (NTRS)

Nossen, E. J.; Starner, E. R.

1974-01-01

A feasibility analysis and trade-offs for a one-way Doppler extractor using digital VCO techniques is presented. The method of Doppler measurement involves the use of a digital phase lock loop; once this loop is locked to the incoming signal, the precise frequency and hence the Doppler component can be determined directly from the contents of the digital control register. The only serious error source is due to internally generated noise. Techniques are presented for minimizing this error source and achieving an accuracy of 0.01 Hz in a one second averaging period. A number of digitally controlled oscillators were analyzed from a performance and complexity point of view. The most promising technique uses an arithmetic synthesizer as a digital waveform generator.

A preliminary comparison of Landsat Thematic Mapper and SPOT-1 HRV multispectral data for estimating coniferous forest volume

NASA Technical Reports Server (NTRS)

Ripple, W. J.; Wang, S.; Isaacson, D. L.; Paine, D. P.

1991-01-01

Digital Landsat Thematic Mapper (TM) and SPOT high-resolution visible (HRV) images of coniferous forest canopies were compared in their relationship to forest wood volume using correlation and regression analyses. Significant inverse relationships were found between softwood volume and the spectral bands from both sensors (P less than 0.01). The highest correlations were between the log of softwood volume and the near-infrared bands.

The Value Versus Volume Yield Problem for Live-Sawn Hardwood Sawlogs

Treesearch

Philip H. Steele; Francis G. Wagner; Lalit Kumar; Philip A. Araman

1993-01-01

The potential conflict between value and volume maximization in sawing hardwood sawlogs by the live sawing method was analyzed. Twenty-four digitally described red oak sawlogs were sawn at the log orientation of highest value yield. Five opening face sawlines were iteratively placed in the sawlog a 1/4-inch intervals and lumber grades, volumes, and values from...

Mapping soil deformation around plant roots using in vivo 4D X-ray Computed Tomography and Digital Volume Correlation.

PubMed

Keyes, S D; Gillard, F; Soper, N; Mavrogordato, M N; Sinclair, I; Roose, T

2016-06-14

The mechanical impedance of soils inhibits the growth of plant roots, often being the most significant physical limitation to root system development. Non-invasive imaging techniques have recently been used to investigate the development of root system architecture over time, but the relationship with soil deformation is usually neglected. Correlative mapping approaches parameterised using 2D and 3D image data have recently gained prominence for quantifying physical deformation in composite materials including fibre-reinforced polymers and trabecular bone. Digital Image Correlation (DIC) and Digital Volume Correlation (DVC) are computational techniques which use the inherent material texture of surfaces and volumes, captured using imaging techniques, to map full-field deformation components in samples during physical loading. Here we develop an experimental assay and methodology for four-dimensional, in vivo X-ray Computed Tomography (XCT) and apply a Digital Volume Correlation (DVC) approach to the data to quantify deformation. The method is validated for a field-derived soil under conditions of uniaxial compression, and a calibration study is used to quantify thresholds of displacement and strain measurement. The validated and calibrated approach is then demonstrated for an in vivo test case in which an extending maize root in field-derived soil was imaged hourly using XCT over a growth period of 19h. This allowed full-field soil deformation data and 3D root tip dynamics to be quantified in parallel for the first time. This fusion of methods paves the way for comparative studies of contrasting soils and plant genotypes, improving our understanding of the fundamental mechanical processes which influence root system development. Copyright © 2016 Elsevier Ltd. All rights reserved.

DMSP Special Sensor Microwave/Imager Calibration/Validation. Volume 1

DTIC Science & Technology

1990-01-01

each channel samples the hot load on every scan and commands a gain change up when the hot load is below 7/16th of the analog to digital converter range...OLS imagery. A threshold blanking technique was used to convert the manual analyses into synthetic digital images containing the cloud truth...should include OLS digital thermal infrared into the analysis. While this will be of use only in clear, relatively dry atmospheric conditions, the

Digital Analytics in Professional Work and Learning

ERIC Educational Resources Information Center

Edwards, Richard; Fenwick, Tara

2016-01-01

In a wide range of fields, professional practice is being transformed by the increasing influence of digital analytics: the massive volumes of big data, and software algorithms that are collecting, comparing and calculating that data to make predictions and even decisions. Researchers in a number of social sciences have been calling attention to…

Games for Learning: Vast Wasteland or a Digital Promise?

ERIC Educational Resources Information Center

Levine, Michael H.; Vaala, Sarah E.

2013-01-01

Research about emerging best practices in the learning sciences points to the potential of deploying digital games as one possible solution to the twin challenges of weak student engagement and the need for more robust achievement in literacy, science, technology, and math. This chapter reviews key cross-cutting themes in this special volume,…

Re-Using Today's Metadata for Tomorrow's Research: Five Practical Examples for Enhancing Access to Digital Collections

ERIC Educational Resources Information Center

Tzoc, Elias

2011-01-01

According to the "Framework of Guidance for Building Good Digital Collections," a good collection is broadly available and avoids unnecessary impediments to use. Two challenges, however, are the constant change in users' expectations and the increasing volume of information in local repositories. Therefore, as academic and research…

Pursuing Digital Literacy in Compulsory Education. New Literacies and Digital Epistemologies. Volume 43

ERIC Educational Resources Information Center

Stergioulas, Lampros K., Ed.; Drenoyianni, Helen, Ed.

2011-01-01

Over the last two decades, advances in information and communication technologies (ICTs) have contributed to the ideological construct of an emerging "knowledge society"--one which places a high value on knowledge and education and promises a better future for humanity. However, the severe economic--and by extension, social and…

Digital 3D Microstructure Analysis of Concrete using X-Ray Micro Computed Tomography SkyScan 1173: A Preliminary Study

NASA Astrophysics Data System (ADS)

Latief, F. D. E.; Mohammad, I. H.; Rarasati, A. D.

2017-11-01

Digital imaging of a concrete sample using high resolution tomographic imaging by means of X-Ray Micro Computed Tomography (μ-CT) has been conducted to assess the characteristic of the sample’s structure. A standard procedure of image acquisition, reconstruction, image processing of the method using a particular scanning device i.e., the Bruker SkyScan 1173 High Energy Micro-CT are elaborated. A qualitative and a quantitative analysis were briefly performed on the sample to deliver some basic ideas of the capability of the system and the bundled software package. Calculation of total VOI volume, object volume, percent of object volume, total VOI surface, object surface, object surface/volume ratio, object surface density, structure thickness, structure separation, total porosity were conducted and analysed. This paper should serve as a brief description of how the device can produce the preferred image quality as well as the ability of the bundled software packages to help in performing qualitative and quantitative analysis.

Laser-based volumetric flow visualization by digital color imaging of a spectrally coded volume.

PubMed

McGregor, T J; Spence, D J; Coutts, D W

2008-01-01

We present the framework for volumetric laser-based flow visualization instrumentation using a spectrally coded volume to achieve three-component three-dimensional particle velocimetry. By delivering light from a frequency doubled Nd:YAG laser with an optical fiber, we exploit stimulated Raman scattering within the fiber to generate a continuum spanning the visible spectrum from 500 to 850 nm. We shape and disperse the continuum light to illuminate a measurement volume of 20 x 10 x 4 mm(3), in which light sheets of differing spectral properties overlap to form an unambiguous color variation along the depth direction. Using a digital color camera we obtain images of particle fields in this volume. We extract the full spatial distribution of particles with depth inferred from particle color. This paper provides a proof of principle of this instrument, examining the spatial distribution of a static field and a spray field of water droplets ejected by the nozzle of an airbrush.

Automatic Intensity-based 3D-to-2D Registration of CT Volume and Dual-energy Digital Radiography for the Detection of Cardiac Calcification

PubMed Central

Chen, Xiang; Gilkeson, Robert; Fei, Baowei

2013-01-01

We are investigating three-dimensional (3D) to two-dimensional (2D) registration methods for computed tomography (CT) and dual-energy digital radiography (DR) for the detection of coronary artery calcification. CT is an established tool for the diagnosis of coronary artery diseases (CADs). Dual-energy digital radiography could be a cost-effective alternative for screening coronary artery calcification. In order to utilize CT as the “gold standard” to evaluate the ability of DR images for the detection and localization of calcium, we developed an automatic intensity-based 3D-to-2D registration method for 3D CT volumes and 2D DR images. To generate digital rendering radiographs (DRR) from the CT volumes, we developed three projection methods, i.e. Gaussian-weighted projection, threshold-based projection, and average-based projection. We tested normalized cross correlation (NCC) and normalized mutual information (NMI) as similarity measurement. We used the Downhill Simplex method as the search strategy. Simulated projection images from CT were fused with the corresponding DR images to evaluate the localization of cardiac calcification. The registration method was evaluated by digital phantoms, physical phantoms, and clinical data sets. The results from the digital phantoms show that the success rate is 100% with mean errors of less 0.8 mm and 0.2 degree for both NCC and NMI. The registration accuracy of the physical phantoms is 0.34 ± 0.27 mm. Color overlay and 3D visualization of the clinical data show that the two images are registered well. This is consistent with the improvement of the NMI values from 0.20 ± 0.03 to 0.25 ± 0.03 after registration. The automatic 3D-to-2D registration method is accurate and robust and may provide a useful tool to evaluate the dual-energy DR images for the detection of coronary artery calcification. PMID:24386527

Automatic Intensity-based 3D-to-2D Registration of CT Volume and Dual-energy Digital Radiography for the Detection of Cardiac Calcification.

PubMed

Chen, Xiang; Gilkeson, Robert; Fei, Baowei

2007-03-03

We are investigating three-dimensional (3D) to two-dimensional (2D) registration methods for computed tomography (CT) and dual-energy digital radiography (DR) for the detection of coronary artery calcification. CT is an established tool for the diagnosis of coronary artery diseases (CADs). Dual-energy digital radiography could be a cost-effective alternative for screening coronary artery calcification. In order to utilize CT as the "gold standard" to evaluate the ability of DR images for the detection and localization of calcium, we developed an automatic intensity-based 3D-to-2D registration method for 3D CT volumes and 2D DR images. To generate digital rendering radiographs (DRR) from the CT volumes, we developed three projection methods, i.e. Gaussian-weighted projection, threshold-based projection, and average-based projection. We tested normalized cross correlation (NCC) and normalized mutual information (NMI) as similarity measurement. We used the Downhill Simplex method as the search strategy. Simulated projection images from CT were fused with the corresponding DR images to evaluate the localization of cardiac calcification. The registration method was evaluated by digital phantoms, physical phantoms, and clinical data sets. The results from the digital phantoms show that the success rate is 100% with mean errors of less 0.8 mm and 0.2 degree for both NCC and NMI. The registration accuracy of the physical phantoms is 0.34 ± 0.27 mm. Color overlay and 3D visualization of the clinical data show that the two images are registered well. This is consistent with the improvement of the NMI values from 0.20 ± 0.03 to 0.25 ± 0.03 after registration. The automatic 3D-to-2D registration method is accurate and robust and may provide a useful tool to evaluate the dual-energy DR images for the detection of coronary artery calcification.

Automatic intensity-based 3D-to-2D registration of CT volume and dual-energy digital radiography for the detection of cardiac calcification

NASA Astrophysics Data System (ADS)

Chen, Xiang; Gilkeson, Robert; Fei, Baowei

2007-03-01

We are investigating three-dimensional (3D) to two-dimensional (2D) registration methods for computed tomography (CT) and dual-energy digital radiography (DR) for the detection of coronary artery calcification. CT is an established tool for the diagnosis of coronary artery diseases (CADs). Dual-energy digital radiography could be a cost-effective alternative for screening coronary artery calcification. In order to utilize CT as the "gold standard" to evaluate the ability of DR images for the detection and localization of calcium, we developed an automatic intensity-based 3D-to-2D registration method for 3D CT volumes and 2D DR images. To generate digital rendering radiographs (DRR) from the CT volumes, we developed three projection methods, i.e. Gaussian-weighted projection, threshold-based projection, and average-based projection. We tested normalized cross correlation (NCC) and normalized mutual information (NMI) as similarity measurement. We used the Downhill Simplex method as the search strategy. Simulated projection images from CT were fused with the corresponding DR images to evaluate the localization of cardiac calcification. The registration method was evaluated by digital phantoms, physical phantoms, and clinical data sets. The results from the digital phantoms show that the success rate is 100% with mean errors of less 0.8 mm and 0.2 degree for both NCC and NMI. The registration accuracy of the physical phantoms is 0.34 +/- 0.27 mm. Color overlay and 3D visualization of the clinical data show that the two images are registered well. This is consistent with the improvement of the NMI values from 0.20 +/- 0.03 to 0.25 +/- 0.03 after registration. The automatic 3D-to-2D registration method is accurate and robust and may provide a useful tool to evaluate the dual-energy DR images for the detection of coronary artery calcification.

[Application possibilities and initial experience with digital volume tomography in hand and wrist imaging].

PubMed

Goerke, Sebastian M; Neubauer, J; Zajonc, H; Thiele, J R; Kotter, E; Langer, M; Stark, G B; Lampert, F M

2015-02-01

During the last decade, DVT (digital volume tomography) imaging has become a widely used standard technique in head and neck imaging. Lower radiation exposure compared to conventional computed tomography (MDCT) has been described. Recently, DVT has been developed as an extremity scanner and as such represents a new imaging technique for hand surgery. We here describe the first 24 months experience with this new imaging modality in hand and wrist imaging by presenting representative cases and by describing the technical background. Furthermore, the method's advantages and disadvantages are discussed with reference to the given literature. © Georg Thieme Verlag KG Stuttgart · New York.

Storage media for computers in radiology

PubMed Central

Dandu, Ravi Varma

2008-01-01

The introduction and wide acceptance of digital technology in medical imaging has resulted in an exponential increase in the amount of data produced by the radiology department. There is an insatiable need for storage space to archive this ever-growing volume of image data. Healthcare facilities should plan the type and size of the storage media that they needed, based not just on the volume of data but also on considerations such as the speed and ease of access, redundancy, security, costs, as well as the longevity of the archival technology. This article reviews the various digital storage media and compares their merits and demerits. PMID:19774182

Implementation and extension of the impulse transfer function method for future application to the space shuttle project. Volume 2: Program description and user's guide

NASA Technical Reports Server (NTRS)

Patterson, G.

1973-01-01

The data processing procedures and the computer programs were developed to predict structural responses using the Impulse Transfer Function (ITF) method. There are three major steps in the process: (1) analog-to-digital (A-D) conversion of the test data to produce Phase I digital tapes (2) processing of the Phase I digital tapes to extract ITF's and storing them in a permanent data bank, and (3) predicting structural responses to a set of applied loads. The analog to digital conversion is performed by a standard package which will be described later in terms of the contents of the resulting Phase I digital tape. Two separate computer programs have been developed to perform the digital processing.

A flight investigation of simulated data-link communications during single-pilot IFR flight. Volume 1: Experimental design and initial test

NASA Technical Reports Server (NTRS)

Parker, J. F., Jr.; Duffy, J. W.; Christensen, D. G.

1981-01-01

A Flight Data Console simulation of a digital communication link to replace the current voice communication system used in air traffic control (ATC) was developed. The study determined how a digital communications system reduces cockpit workload, improve, flight proficiency, and is acceptable to general aviation pilots. It is shown that instrument flight, including approach and landing, can be accomplished by using a digital data link system for ATC communication.

Harvard Education Letter, 2002.

ERIC Educational Resources Information Center

Gordon, David T., Editor

2002-01-01

This document is comprised of the 6 issues in volume 18 of the Harvard Education Letter, a bimonthly newsletter addressing current issues in elementary and secondary education. Articles in this volume include the following: (1) January/February--"Curriculum Access in the Digital Age" (David T. Gordon) and "Using Charters To Improve…

Fully digital data processing during cardiovascular implantable electronic device follow-up in a high-volume tertiary center.

PubMed

Staudacher, Ingo; Nalpathamkalam, Asha Roy; Uhlmann, Lorenz; Illg, Claudius; Seehausen, Sebastian; Akhavanpoor, Mohammadreza; Buchauer, Anke; Geis, Nicolas; Lugenbiel, Patrick; Schweizer, Patrick A; Xynogalos, Panagiotis; Zylla, Maura M; Scholz, Eberhard; Zitron, Edgar; Katus, Hugo A; Thomas, Dierk

2017-10-11

Increasing numbers of patients with cardiovascular implantable electronic devices (CIEDs) and limited follow-up capacities highlight unmet challenges in clinical electrophysiology. Integrated software (MediConnect ® ) enabling fully digital processing of device interrogation data has been commercially developed to facilitate follow-up visits. We sought to assess feasibility of fully digital data processing (FDDP) during ambulatory device follow-up in a high-volume tertiary hospital to provide guidance for future users of FDDP software. A total of 391 patients (mean age, 70 years) presenting to the outpatient department for routine device follow-up were analyzed (pacemaker, 44%; implantable cardioverter defibrillator, 39%; cardiac resynchronization therapy device, 16%). Quality of data transfer and follow-up duration were compared between digital (n = 265) and manual processing of device data (n = 126). Digital data import was successful, complete and correct in 82% of cases when early software versions were used. When using the most recent software version the rate of successful digital data import increased to 100%. Software-based import of interrogation data was complete and without failure in 97% of cases. The mean duration of a follow-up visit did not differ between the two groups (digital 18.7 min vs. manual data transfer 18.2 min). FDDP software was successfully implemented into the ambulatory follow-up of patients with implanted pacemakers and defibrillators. Digital data import into electronic patient management software was feasible and supported the physician's workflow. The total duration of follow-up visits comprising technical device interrogation and clinical actions was not affected in the present tertiary center outpatient cohort.

Data collection system. Volume 1, Overview and operators manual; Volume 2, Maintenance manual; Appendices

DOE Office of Scientific and Technical Information (OSTI.GOV)

Caudell, R.B.; Bauder, M.E.; Boyer, W.B.

1993-09-01

Sandia National Laboratories (SNL) Instrumentation Development Department was tasked by the Defense Nuclear Agency (DNA) to record data on Tektronix RTD720 Digitizers on the HUNTERS TROPHY field test conducted at the Nevada Test Site (NTS) on September 18, 1992. This report contains a overview and description of the computer hardware and software that was used to acquire, reduce, and display the data. The document is divided into two volumes: an overview and operators manual (Volume 1) and a maintenance manual (Volume 2).

Self-digitization microfluidic chip for absolute quantification of mRNA in single cells.

PubMed

Thompson, Alison M; Gansen, Alexander; Paguirigan, Amy L; Kreutz, Jason E; Radich, Jerald P; Chiu, Daniel T

2014-12-16

Quantification of mRNA in single cells provides direct insight into how intercellular heterogeneity plays a role in disease progression and outcomes. Quantitative polymerase chain reaction (qPCR), the current gold standard for evaluating gene expression, is insufficient for providing absolute measurement of single-cell mRNA transcript abundance. Challenges include difficulties in handling small sample volumes and the high variability in measurements. Microfluidic digital PCR provides far better sensitivity for minute quantities of genetic material, but the typical format of this assay does not allow for counting of the absolute number of mRNA transcripts samples taken from single cells. Furthermore, a large fraction of the sample is often lost during sample handling in microfluidic digital PCR. Here, we report the absolute quantification of single-cell mRNA transcripts by digital, one-step reverse transcription PCR in a simple microfluidic array device called the self-digitization (SD) chip. By performing the reverse transcription step in digitized volumes, we find that the assay exhibits a linear signal across a wide range of total RNA concentrations and agrees well with standard curve qPCR. The SD chip is found to digitize a high percentage (86.7%) of the sample for single-cell experiments. Moreover, quantification of transferrin receptor mRNA in single cells agrees well with single-molecule fluorescence in situ hybridization experiments. The SD platform for absolute quantification of single-cell mRNA can be optimized for other genes and may be useful as an independent control method for the validation of mRNA quantification techniques.

Classroom Technology: Where Schools Stand. Technology Counts, 2017. Education Week. Volume 36, Issue 35

ERIC Educational Resources Information Center

Bushweller, Kevin C., Ed.

2017-01-01

This report, the 20th edition of "Technology Counts," examines how schools are tackling tech training for teachers, "passive" vs. "active" use of digital tools, and online learning needs. Contents include: (1) Tracking 20 Years of Change in Ed Tech (Kevin C. Bushweller); (2) Poor Students Face Digital Divide in How…

Children's Virtual Play Worlds Culture, Learning, and Participation. New Literacies and Digital Epistemologies. Volume 58

ERIC Educational Resources Information Center

Burke, Anne, Ed.; Marsh, Jackie, Ed.

2013-01-01

As children's digital lives become more relevant to schools and educators, the question of play and learning is being revisited in new and interesting ways. "Children's Virtual Play Worlds: Culture, Learning, and Participation" provides a more reasoned account of children's play engagements in virtual worlds through a number of scholarly…

Digital Advances Reshaping K-12 Testing. Technology Counts, 2014. Education Week. Volume 33 Number 25

ERIC Educational Resources Information Center

Edwards, Virginia B., Ed.

2014-01-01

Figuring out how to use digital tools to transform testing requires a willingness to invest in new technologies and the patience to experiment with novel approaches, a commitment to ongoing professional development and reliable technical support, and an openness to learn from mistakes. Whatever bumpy ride this technological journey takes, experts…

A Comparative Study of the Precision of Carstens and Northern Digital Instruments Electromagnetic Articulographs

ERIC Educational Resources Information Center

Savariaux, Christophe; Badin, Pierre; Samson, Adeline; Gerber, Silvain

2017-01-01

Purpose: This study compares the precision of the electromagnetic articulographs used in speech research: Northern Digital Instruments' Wave and Carstens' AG200, AG500, and AG501 systems. Method: The fluctuation of distances between 3 pairs of sensors attached to a manually rotated device that can position them inside the measurement volumes was…

Information Processing Techniques Program. Volume II. Communications- Adaptive Internetting

DTIC Science & Technology

1977-09-30

LABORATORY INFORMATION PROCESSING TECHNIQUES PROGRAM VOLUME II: COMMUNICATIONS-ADAPTIVE INTERNETTING I SEMIANNUAL TECHNICAL SUMMARY REPORT TO THE...MASSACHUSETTS ABSTRACT This repori describes work performed on the Communications-Adaptive Internetting program sponsored by the Information ... information processing techniques network speech terminal communicatlons-adaptive internetting 04 links digital voice communications time-varying

The Specific Volumes and Viscosities of the Ni-Zr Liquid Alloys and their Correlation with the Glass Formability of the Alloys

NASA Technical Reports Server (NTRS)

Ohsaka, K.; Chung, S. K.; Rhim, W. K.

1997-01-01

The specific volumes and viscosities of the Ni-Zr liquid alloys as a function of temperature are determined by employing a digitizing technique and numeric analysis methods applied to the optical images of the electrostatically levitated liquid alloys.

A DDC Bibliography on Computers in Information Sciences. Volume II. Information Sciences Series.

ERIC Educational Resources Information Center

Defense Documentation Center, Alexandria, VA.

The unclassified and unlimited bibliography compiles references dealing specifically with the role of computers in information sciences. The volume contains 239 annotated references grouped under three major headings: Artificial and Programming Languages, Computer Processing of Analog Data, and Computer Processing of Digital Data. The references…

Comparison of traditional nondestructive analysis of RERTR fuel plates with digital radiographic techniques

DOE Office of Scientific and Technical Information (OSTI.GOV)

Davidsmeier, T.; Koehl, R.; Lanham, R.

2008-07-15

The current design and fabrication process for RERTR fuel plates utilizes film radiography during the nondestructive testing and characterization. Digital radiographic methods offer a potential increases in efficiency and accuracy. The traditional and digital radiographic methods are described and demonstrated on a fuel plate constructed with and average of 51% by volume fuel using the dispersion method. Fuel loading data from each method is analyzed and compared to a third baseline method to assess accuracy. The new digital method is shown to be more accurate, save hours of work, and provide additional information not easily available in the traditional method.more » Additional possible improvements suggested by the new digital method are also raised. (author)« less

NMCS Information Processing System 360 Formatted File System (NIPS 360 FFS). Users Manual. Volume 1. Introduction to File Concepts

DTIC Science & Technology

1978-09-01

input source language (other than ?S). Used in double form, negates an FFT spcification for a subroutine. / (Slash) Used to separate numeric digits (V-l...1) represents the digits 1-999 and also digits followed by a letter, e.g., LINE1OA ’. Th, E311owing name prefiKes are not allowed: PSSQ, VSEr, VSZ...b ZERO OUT 6 LA 6,12 (6) ADD 12 TO 6 PUT IN REG b 4’MOVF INPUT DATE rC WORK APEA, REFORMAT DD AND YY 0C)NVERr TWO DIGIT MONTH TO SYMBOLIC THREE

Volume Holographic Storage of Digital Data Implemented in Photorefractive Media

NASA Astrophysics Data System (ADS)

Heanue, John Frederick

A holographic data storage system is fundamentally different from conventional storage devices. Information is recorded in a volume, rather than on a two-dimensional surface. Data is transferred in parallel, on a page-by -page basis, rather than serially. These properties, combined with a limited need for mechanical motion, lead to the potential for a storage system with high capacity, fast transfer rate, and short access time. The majority of previous volume holographic storage experiments have involved direct storage and retrieval of pictorial information. Success in the development of a practical holographic storage device requires an understanding of the performance capabilities of a digital system. This thesis presents a number of contributions toward this goal. A description of light diffraction from volume gratings is given. The results are used as the basis for a theoretical and numerical analysis of interpage crosstalk in both angular and wavelength multiplexed holographic storage. An analysis of photorefractive grating formation in photovoltaic media such as lithium niobate is presented along with steady-state expressions for the space-charge field in thermal fixing. Thermal fixing by room temperature recording followed by ion compensation at elevated temperatures is compared to simultaneous recording and compensation at high temperature. In particular, the tradeoff between diffraction efficiency and incomplete Bragg matching is evaluated. An experimental investigation of orthogonal phase code multiplexing is described. Two unique capabilities, the ability to perform arithmetic operations on stored data pages optically, rather than electronically, and encrypted data storage, are demonstrated. A comparison of digital signal representations, or channel codes, is carried out. The codes are compared in terms of bit-error rate performance at constant capacity. A well-known one-dimensional digital detection technique, maximum likelihood sequence estimation, is extended for use in a two-dimensional page format memory. The effectiveness of the technique in a system corrupted by intersymbol interference is investigated both experimentally and through numerical simulations. The experimental implementation of a fully-automated multiple page digital holographic storage system is described. Finally, projections of the performance limits of holographic data storage are made taking into account typical noise sources.

A flexible and accurate digital volume correlation method applicable to high-resolution volumetric images

NASA Astrophysics Data System (ADS)

Pan, Bing; Wang, Bo

2017-10-01

Digital volume correlation (DVC) is a powerful technique for quantifying interior deformation within solid opaque materials and biological tissues. In the last two decades, great efforts have been made to improve the accuracy and efficiency of the DVC algorithm. However, there is still a lack of a flexible, robust and accurate version that can be efficiently implemented in personal computers with limited RAM. This paper proposes an advanced DVC method that can realize accurate full-field internal deformation measurement applicable to high-resolution volume images with up to billions of voxels. Specifically, a novel layer-wise reliability-guided displacement tracking strategy combined with dynamic data management is presented to guide the DVC computation from slice to slice. The displacements at specified calculation points in each layer are computed using the advanced 3D inverse-compositional Gauss-Newton algorithm with the complete initial guess of the deformation vector accurately predicted from the computed calculation points. Since only limited slices of interest in the reference and deformed volume images rather than the whole volume images are required, the DVC calculation can thus be efficiently implemented on personal computers. The flexibility, accuracy and efficiency of the presented DVC approach are demonstrated by analyzing computer-simulated and experimentally obtained high-resolution volume images.

Digital image analysis of testicular and prostatic ultrasonographic echogencity and heterogeneity in dogs and the relation to semen quality.

PubMed

Moxon, Rachel; Bright, Lucy; Pritchard, Beth; Bowen, I Mark; de Souza, Mírley Barbosa; da Silva, Lúcia Daniel Machado; England, Gary C W

2015-09-01

A semi-automated ultrasonographic method was developed to measure echogenicity and heterogeneity of the testes and prostate gland and relationships of these measures with semen quality were assessed in 43 fertile dogs. The relationship between animal age and body weight upon the volume of the testes, epididymal tail volume and prostate volume were also established. Mean testicular echogenicity was negatively correlated with the percentage of morphologically normal live spermatozoa (more echogenic testes were associated with fewer normal sperm) but not with any other semen quality measure. Mean testicular heterogeneity was positively correlated with the total spermatozoal output (more heterogenous testes, being those with anechoic parenchyma and prominent echogenic stippling, were associated with greater sperm output) but not with any other semen quality measure. There was no relationship between either mean prostatic echogenicity or mean prostatic heterogeneity and any semen quality measure. There was no relationship between age and any testicular or prostatic parameter; however bodyweight was significantly correlated with total testicular volume, total epididymal tail volume and total prostatic volume. Testicular and prostatic ultrasonographic echogenicity and heterogeneity can be objectively assessed using digital image analysis and testicular echogenicity and heterogeneity may be useful adjunct measurements in a breeding soundness examination. Copyright © 2015 Elsevier B.V. All rights reserved.

The production of digital and printed resources from multiple modalities using visualization and three-dimensional printing techniques.

PubMed

Shui, Wuyang; Zhou, Mingquan; Chen, Shi; Pan, Zhouxian; Deng, Qingqiong; Yao, Yong; Pan, Hui; He, Taiping; Wang, Xingce

2017-01-01

Virtual digital resources and printed models have become indispensable tools for medical training and surgical planning. Nevertheless, printed models of soft tissue organs are still challenging to reproduce. This study adopts open source packages and a low-cost desktop 3D printer to convert multiple modalities of medical images to digital resources (volume rendering images and digital models) and lifelike printed models, which are useful to enhance our understanding of the geometric structure and complex spatial nature of anatomical organs. Neuroimaging technologies such as CT, CTA, MRI, and TOF-MRA collect serial medical images. The procedures for producing digital resources can be divided into volume rendering and medical image reconstruction. To verify the accuracy of reconstruction, this study presents qualitative and quantitative assessments. Subsequently, digital models are archived as stereolithography format files and imported to the bundled software of the 3D printer. The printed models are produced using polylactide filament materials. We have successfully converted multiple modalities of medical images to digital resources and printed models for both hard organs (cranial base and tooth) and soft tissue organs (brain, blood vessels of the brain, the heart chambers and vessel lumen, and pituitary tumor). Multiple digital resources and printed models were provided to illustrate the anatomical relationship between organs and complicated surrounding structures. Three-dimensional printing (3DP) is a powerful tool to produce lifelike and tangible models. We present an available and cost-effective method for producing both digital resources and printed models. The choice of modality in medical images and the processing approach is important when reproducing soft tissue organs models. The accuracy of the printed model is determined by the quality of organ models and 3DP. With the ongoing improvement of printing techniques and the variety of materials available, 3DP will become an indispensable tool in medical training and surgical planning.

The NASA digital VGH program: Exploration of methods and final results. Volume 2: L 1011 data 1978-1979: 1619 hours

NASA Technical Reports Server (NTRS)

Crabill, Norman L.

1989-01-01

Data obtained from the digital flight data recorder system of a L 1011 aircraft in 914 flights and 1619 hours of airline revenue operations are presented. Data on conditions with flap deployment and autopilot use are given. In addition, acceleration statistics are presented from 23 hours on nonrevenue flights.

Laboratory Instrumentation Design Research for Scalable Next Generation Epitaxy: Non-Equilibrium Wide Application Epitaxial Patterning by Intelligent Control (NEW-EPIC). Volume 1. 3D Composition/Doping Control via Micromiror Patterned Deep UV Photodesorption: Revolutionary in situ Characterization/Control

DTIC Science & Technology

2009-02-19

magnesium dopant concentration. A digital micromirror device is introduced to pattern incident UV radiation during InGaN growth, demonstrating that the...magnesium dopant concentration. A digital micromirror device is introduced to pattern incident UV radiation during InGaN growth, demonstrating that the...successful compositional patterning of InGaN using in situ digital micromirror device (DMD) patterning of ultraviolet (UV

NASA/BLM APT, phase 2. Volume 2: Technology demonstration. [Arizona

NASA Technical Reports Server (NTRS)

1981-01-01

Techniques described include: (1) steps in the preprocessing of LANDSAT data; (2) the training of a classifier; (3) maximum likelihood classification and precision; (4) geometric correction; (5) class description; (6) digitizing; (7) digital terrain data; (8) an overview of sample design; (9) allocation and selection of primary sample units; (10) interpretation of secondary sample units; (11) data collection ground plots; (12) data reductions; (13) analysis for productivity estimation and map verification; (14) cost analysis; and (150) LANDSAT digital products. The evaluation of the pre-inventory planning for P.J. is included.

Development of optimized techniques and requirements for computer enhancement of structural weld radiographs. Volume 1: Technical report

NASA Technical Reports Server (NTRS)

Adams, J. R.; Hawley, S. W.; Peterson, G. R.; Salinger, S. S.; Workman, R. A.

1971-01-01

A hardware and software specification covering requirements for the computer enhancement of structural weld radiographs was considered. Three scanning systems were used to digitize more than 15 weld radiographs. The performance of these systems was evaluated by determining modulation transfer functions and noise characteristics. Enhancement techniques were developed and applied to the digitized radiographs. The scanning parameters of spot size and spacing and film density were studied to optimize the information content of the digital representation of the image.

Holographic Compact Disk Read-Only Memories

NASA Technical Reports Server (NTRS)

Liu, Tsuen-Hsi

1996-01-01

Compact disk read-only memories (CD-ROMs) of proposed type store digital data in volume holograms instead of in surface differentially reflective elements. Holographic CD-ROM consist largely of parts similar to those used in conventional CD-ROMs. However, achieves 10 or more times data-storage capacity and throughput by use of wavelength-multiplexing/volume-hologram scheme.

A diffusion tensor imaging tractography algorithm based on Navier-Stokes fluid mechanics.

PubMed

Hageman, Nathan S; Toga, Arthur W; Narr, Katherine L; Shattuck, David W

2009-03-01

We introduce a fluid mechanics based tractography method for estimating the most likely connection paths between points in diffusion tensor imaging (DTI) volumes. We customize the Navier-Stokes equations to include information from the diffusion tensor and simulate an artificial fluid flow through the DTI image volume. We then estimate the most likely connection paths between points in the DTI volume using a metric derived from the fluid velocity vector field. We validate our algorithm using digital DTI phantoms based on a helical shape. Our method segmented the structure of the phantom with less distortion than was produced using implementations of heat-based partial differential equation (PDE) and streamline based methods. In addition, our method was able to successfully segment divergent and crossing fiber geometries, closely following the ideal path through a digital helical phantom in the presence of multiple crossing tracts. To assess the performance of our algorithm on anatomical data, we applied our method to DTI volumes from normal human subjects. Our method produced paths that were consistent with both known anatomy and directionally encoded color images of the DTI dataset.

A Diffusion Tensor Imaging Tractography Algorithm Based on Navier-Stokes Fluid Mechanics

PubMed Central

Hageman, Nathan S.; Toga, Arthur W.; Narr, Katherine; Shattuck, David W.

2009-01-01

We introduce a fluid mechanics based tractography method for estimating the most likely connection paths between points in diffusion tensor imaging (DTI) volumes. We customize the Navier-Stokes equations to include information from the diffusion tensor and simulate an artificial fluid flow through the DTI image volume. We then estimate the most likely connection paths between points in the DTI volume using a metric derived from the fluid velocity vector field. We validate our algorithm using digital DTI phantoms based on a helical shape. Our method segmented the structure of the phantom with less distortion than was produced using implementations of heat-based partial differential equation (PDE) and streamline based methods. In addition, our method was able to successfully segment divergent and crossing fiber geometries, closely following the ideal path through a digital helical phantom in the presence of multiple crossing tracts. To assess the performance of our algorithm on anatomical data, we applied our method to DTI volumes from normal human subjects. Our method produced paths that were consistent with both known anatomy and directionally encoded color (DEC) images of the DTI dataset. PMID:19244007

Comparison of pre/post-operative CT image volumes to preoperative digitization of partial hepatectomies: a feasibility study in surgical validation

NASA Astrophysics Data System (ADS)

Dumpuri, Prashanth; Clements, Logan W.; Li, Rui; Waite, Jonathan M.; Stefansic, James D.; Geller, David A.; Miga, Michael I.; Dawant, Benoit M.

2009-02-01

Preoperative planning combined with image-guidance has shown promise towards increasing the accuracy of liver resection procedures. The purpose of this study was to validate one such preoperative planning tool for four patients undergoing hepatic resection. Preoperative computed tomography (CT) images acquired before surgery were used to identify tumor margins and to plan the surgical approach for resection of these tumors. Surgery was then performed with intraoperative digitization data acquire by an FDA approved image-guided liver surgery system (Pathfinder Therapeutics, Inc., Nashville, TN). Within 5-7 days after surgery, post-operative CT image volumes were acquired. Registration of data within a common coordinate reference was achieved and preoperative plans were compared to the postoperative volumes. Semi-quantitative comparisons are presented in this work and preliminary results indicate that significant liver regeneration/hypertrophy in the postoperative CT images may be present post-operatively. This could challenge pre/post operative CT volume change comparisons as a means to evaluate the accuracy of preoperative surgical plans.

Computer program system for dynamic simulation and stability analysis of passive and actively controlled spacecraft. Volume 1. Theory

NASA Technical Reports Server (NTRS)

Bodley, C. S.; Devers, D. A.; Park, C. A.

1975-01-01

A theoretical development and associated digital computer program system is presented. The dynamic system (spacecraft) is modeled as an assembly of rigid and/or flexible bodies not necessarily in a topological tree configuration. The computer program system may be used to investigate total system dynamic characteristics including interaction effects between rigid and/or flexible bodies, control systems, and a wide range of environmental loadings. Additionally, the program system may be used for design of attitude control systems and for evaluation of total dynamic system performance including time domain response and frequency domain stability analyses. Volume 1 presents the theoretical developments including a description of the physical system, the equations of dynamic equilibrium, discussion of kinematics and system topology, a complete treatment of momentum wheel coupling, and a discussion of gravity gradient and environmental effects. Volume 2, is a program users' guide and includes a description of the overall digital program code, individual subroutines and a description of required program input and generated program output. Volume 3 presents the results of selected demonstration problems that illustrate all program system capabilities.

Comparison of Computational Approaches for Rapid Aerodynamic Assessment of Small UAVs

NASA Technical Reports Server (NTRS)

Shafer, Theresa C.; Lynch, C. Eric; Viken, Sally A.; Favaregh, Noah; Zeune, Cale; Williams, Nathan; Dansie, Jonathan

2014-01-01

Computational Fluid Dynamic (CFD) methods were used to determine the basic aerodynamic, performance, and stability and control characteristics of the unmanned air vehicle (UAV), Kahu. Accurate and timely prediction of the aerodynamic characteristics of small UAVs is an essential part of military system acquisition and air-worthiness evaluations. The forces and moments of the UAV were predicted using a variety of analytical methods for a range of configurations and conditions. The methods included Navier Stokes (N-S) flow solvers (USM3D, Kestrel and Cobalt) that take days to set up and hours to converge on a single solution; potential flow methods (PMARC, LSAERO, and XFLR5) that take hours to set up and minutes to compute; empirical methods (Datcom) that involve table lookups and produce a solution quickly; and handbook calculations. A preliminary aerodynamic database can be developed very efficiently by using a combination of computational tools. The database can be generated with low-order and empirical methods in linear regions, then replacing or adjusting the data as predictions from higher order methods are obtained. A comparison of results from all the data sources as well as experimental data obtained from a wind-tunnel test will be shown and the methods will be evaluated on their utility during each portion of the flight envelope.

Control surface hinge moment prediction using computational fluid dynamics

NASA Astrophysics Data System (ADS)

Simpson, Christopher David

The following research determines the feasibility of predicting control surface hinge moments using various computational methods. A detailed analysis is conducted using a 2D GA(W)-1 airfoil with a 20% plain flap. Simple hinge moment prediction methods are tested, including empirical Datcom relations and XFOIL. Steady-state and time-accurate turbulent, viscous, Navier-Stokes solutions are computed using Fun3D. Hinge moment coefficients are computed. Mesh construction techniques are discussed. An adjoint-based mesh adaptation case is also evaluated. An NACA 0012 45-degree swept horizontal stabilizer with a 25% elevator is also evaluated using Fun3D. Results are compared with experimental wind-tunnel data obtained from references. Finally, the costs of various solution methods are estimated. Results indicate that while a steady-state Navier-Stokes solution can accurately predict control surface hinge moments for small angles of attack and deflection angles, a time-accurate solution is necessary to accurately predict hinge moments in the presence of flow separation. The ability to capture the unsteady vortex shedding behavior present in moderate to large control surface deflections is found to be critical to hinge moment prediction accuracy. Adjoint-based mesh adaptation is shown to give hinge moment predictions similar to a globally-refined mesh for a steady-state 2D simulation.

Whole-slide imaging in pathology: the potential impact on PACS

NASA Astrophysics Data System (ADS)

Horii, Steven C.

2007-03-01

Pathology, the medical specialty charged with the evaluation of macroscopic and microscopic aspects of disease, is increasingly turning to digital imaging. While the conventional tissue blocks and glass slides form an "archive" that pathology departments must maintain, digital images acquired from microscopes or digital slide scanners are increasingly used for telepathology, consultation, and intra-facility communication. Since many healthcare facilities are moving to "enterprise PACS" with departments in addition to radiology using the infrastructure of such systems, some understanding of the potential of whole-slide digital images is important. Network and storage designers, in particular, are very likely to be impacted if a significant number of such images are to be moved on, or stored (even temporarily) in, enterprise PACS. As an example, a typical commercial whole-slide imaging system typically generates 15 gigabytes per slide scanned (per focal plane). Many of these whole-slide scanners have a throughput of 1000 slides per day. If that full capacity is used and all the resulting digital data is moved to the enterprise PACS, it amounts to 15 terabytes per day; the amount of data a large radiology department might generate in a year or two. This paper will review both the clinical scenarios of whole-slide imaging as well as the resulting data volumes. The author will emphasize the potential PACS infrastructure impact of such huge data volumes.

WHOI and SIO (I): Next Steps toward Multi-Institution Archiving of Shipboard and Deep Submergence Vehicle Data

NASA Astrophysics Data System (ADS)

Detrick, R. S.; Clark, D.; Gaylord, A.; Goldsmith, R.; Helly, J.; Lemmond, P.; Lerner, S.; Maffei, A.; Miller, S. P.; Norton, C.; Walden, B.

2005-12-01

The Scripps Institution of Oceanography (SIO) and the Woods Hole Oceanographic Institution (WHOI) have joined forces with the San Diego Supercomputer Center to build a testbed for multi-institutional archiving of shipboard and deep submergence vehicle data. Support has been provided by the Digital Archiving and Preservation program funded by NSF/CISE and the Library of Congress. In addition to the more than 92,000 objects stored in the SIOExplorer Digital Library, the testbed will provide access to data, photographs, video images and documents from WHOI ships, Alvin submersible and Jason ROV dives, and deep-towed vehicle surveys. An interactive digital library interface will allow combinations of distributed collections to be browsed, metadata inspected, and objects displayed or selected for download. The digital library architecture, and the search and display tools of the SIOExplorer project, are being combined with WHOI tools, such as the Alvin Framegrabber and the Jason Virtual Control Van, that have been designed using WHOI's GeoBrowser to handle the vast volumes of digital video and camera data generated by Alvin, Jason and other deep submergence vehicles. Notions of scalability will be tested, as data volumes range from 3 CDs per cruise to 200 DVDs per cruise. Much of the scalability of this proposal comes from an ability to attach digital library data and metadata acquisition processes to diverse sensor systems. We are able to run an entire digital library from a laptop computer as well as from supercomputer-center-size resources. It can be used, in the field, laboratory or classroom, covering data from acquisition-to-archive using a single coherent methodology. The design is an open architecture, supporting applications through well-defined external interfaces maintained as an open-source effort for community inclusion and enhancement.

Analysis of potential debris flow source areas on Mount Shasta, California, by using airborne and satellite remote sensing data

USGS Publications Warehouse

Crowley, J.K.; Hubbard, B.E.; Mars, J.C.

2003-01-01

Remote sensing data from NASA's Airborne Visible/Infrared Imaging Spectrometer (AVIRIS) and the first spaceborne imaging spectrometer, Hyperion, show hydrothermally altered rocks mainly composed of natroalunite, kaolinite, cristobalite, and gypsum on both the Mount Shasta and Shastina cones. Field observations indicate that much of the visible altered rock consists of talus material derived from fractured rock zones within and adjacent to dacitic domes and nearby lava flows. Digital elevation data were utilized to distinguish steeply sloping altered bedrock from more gently sloping talus materials. Volume modeling based on the imagery and digital elevation data indicate that Mount Shasta drainage systems contain moderate volumes of altered rock, a result that is consistent with Mount Shasta's Holocene record of mostly small to moderate debris flows. Similar modeling for selected areas at Mount Rainier and Mount Adams, Washington, indicates larger altered rock volumes consistent with the occurrence of much larger Holocene debris flows at those volcanoes. The availability of digital elevation and spectral data from spaceborne sensors, such as Hyperion and the Advanced Spaceborne Thermal Emission and Reflectance Radiometer (ASTER), greatly expands opportunities for studying potential debris flow source characteristics at stratovolcanoes around the world. ?? 2003 Elsevier Inc. All rights reserved.

An application of digital image processing techniques to the characterization of liquid petroleum gas (LPG) spray

NASA Astrophysics Data System (ADS)

Qi, Y. L.; Xu, B. Y.; Cai, S. L.

2006-12-01

To control fuel injection, optimize combustion and reduce emissions for LPG (liquefied petroleum gas) engines, it is necessary and important to understand the characteristics of LPG sprays. The present work investigates the geometry of LPG sprays, including spray tip penetration, spray angle, projected spray area and spray volume, by using schlieren photography and digital image processing techniques. Two types of single nozzle injectors were studied, with the same nozzle diameter, but one with and one without a double-hole flow-split head. A code developed to analyse the results directly from the digitized images is shown to be more accurate and efficient than manual measurement and analysis. Test results show that a higher injection pressure produces a longer spray tip penetration, a larger projected spray area and spray volume, but a smaller spray cone angle. The injector with the double-hole split-head nozzle produces better atomization and shorter tip penetration at medium and late injection times, but longer tip penetration in the early stage.

Digital stereo-holographic microscopy for studying three-dimensional particle dynamics

NASA Astrophysics Data System (ADS)

Byeon, Hyeokjun; Go, Taesik; Lee, Sang Joon

2018-06-01

A digital stereo-holographic microscopy (DsHM) with two viewing angles is proposed to measure 3D information of microscale particles. This approach includes two volumetric recordings and numerical reconstruction, and it involves the combination of separately reconstructed holograms. The 3D positional information of a particle was determined by searching the center of the overlapped reconstructed volume. After confirming the proposed technique using static spherical particles, the 3D information of moving particles suspended in a Hagen-Poiseiulle flow was successfully obtained. Moreover, the 3D information of nonspherical particles, including ellipsoidal particles and red blood cells, were measured using the proposed technique. In addition to 3D positional information, the orientation and shape of the test samples were obtained from the plane images by slicing the overlapped volume perpendicular to the directions of the image recordings. This DsHM technique will be useful in analyzing the 3D dynamic behavior of various nonspherical particles, which cannot be measured by conventional digital holographic microscopy.

Understanding Digital Note-Taking Practice for Visualization.

PubMed

Willett, Wesley; Goffin, Pascal; Isenberg, Petra

2015-05-13

We present results and design implications from a study of digital note-taking practice to examine how visualization can support revisitation, reflection, and collaboration around notes. As digital notebooks become common forms of external memory, keeping track of volumes of content is increasingly difficult. Information visualization tools can help give note-takers an overview of their content and allow them to explore diverse sets of notes, find and organize related content, and compare their notes with their collaborators. To ground the design of such tools, we conducted a detailed mixed-methods study of digital note-taking practice. We identify a variety of different editing, organization, and sharing methods used by digital note-takers, many of which result in notes becoming "lost in the pile''. These findings form the basis for our design considerations that examine how visualization can support the revisitation, organization, and sharing of digital notes.

Fundamentals handbook of electrical and computer engineering. Volume 1 Circuits fields and electronics

NASA Astrophysics Data System (ADS)

Chang, S. S. L.

State of the art technology in circuits, fields, and electronics is discussed. The principles and applications of these technologies to industry, digital processing, microwave semiconductors, and computer-aided design are explained. Important concepts and methodologies in mathematics and physics are reviewed, and basic engineering sciences and associated design methods are dealt with, including: circuit theory and the design of magnetic circuits and active filter synthesis; digital signal processing, including FIR and IIR digital filter design; transmission lines, electromagnetic wave propagation and surface acoustic wave devices. Also considered are: electronics technologies, including power electronics, microwave semiconductors, GaAs devices, and magnetic bubble memories; digital circuits and logic design.

A preliminary comparison of Landsat Thematic Mapper and SPOT-1 HRV multispectral data for estimating coniferous forest volume

NASA Technical Reports Server (NTRS)

Ripple, William J.; Wang, S.; Isaacson, Dennis L.; Paine, D. P.

1995-01-01

Digital Landsat Thematic Mapper (TM) and Satellite Probatoire d'Observation de la Terre (SPOT) High Resolution Visible (HRV) images of coniferous forest canopies were compared in their relationship to forest wood volume using correlation and regression analyses. Significant inverse relationships were found between softwood volume and the spectral bands from both sensors (P less than 0.01). The highest correlations were between the log of softwood volume and the near-infrared bands (HRV band 3, r = -0.89; TM band 4, r = -0.83).

Learning the Digital Way: Evaluating Progress, Tackling Challenges. Technology Counts, 2015. Education Week. Volume 34, Number 35

ERIC Educational Resources Information Center

Edwards, Virginia B., Ed.

2015-01-01

Lofty ed-tech visions are always tempered by reality. Unexpected problems that arose during a launch of a 1-to-1 computing program and ambitious digital curriculum initiative in Los Angeles led to the dialing back of the effort. Financial, legal, and managerial repercussions continue to swirl in the wake. These problems should not prevent schools…

Formal Methods for Privacy

DTIC Science & Technology

2009-09-01

Review, 39:962, 1964. [8] D. Chaum . Secret ballot receipts: True voter-verifiable elections. IEEE J. Security and Privacy, pages 38–47, 2004. [9...TCC 2005), pages 363–385, 2005. [10] David Clark, Sebastian Hunt, and Pasquale Malacaria. A static analysis for quantifying in- formation flow in a... David Buckingham, editor, MacArthur Foundation Series on Digital Learning– Youth, Identity, Digital Media Volume, Cambridge, MA, 2007. MIT Press. 11

Coupled Physical and Digital Cadaver Dissection Followed by a Visual Test Protocol Provides Insights into the Nature of Anatomical Knowledge and Its Evaluation

ERIC Educational Resources Information Center

Hisley, Kenneth C.; Anderson, Larry D.; Smith, Stacy E.; Kavic, Stephen M.; Tracy, J. Kathleen

2008-01-01

This research effort compared and contrasted two conceptually different methods for the exploration of human anatomy in the first-year dissection laboratory by accomplished students: "physical" dissection using an embalmed cadaver and "digital" dissection using three-dimensional volume modeling of whole-body CT and MRI image sets acquired using…

Guidance, Navigation and Control Digital Emulation Technology Laboratory. Volume 1. Part 1. Task 1: Digital Emulation Technology Laboratory

DTIC Science & Technology

1991-09-27

complex floating-point functions in a fraction of the time used by the best supercomputers on the market today. These co-processing boards "piggy-back...by the VNIX-based DECLARE program. Ve’ ctLptieu du te, tedi the new verion with main programs that noi, include onlN the variablc required wkith each

KM3NeT Digital Optical Module electronics

NASA Astrophysics Data System (ADS)

Real, Diego

2016-04-01

The KM3NeT collaboration is currently building of a neutrino telescope with a volume of several cubic kilometres at the bottom of the Mediterranean Sea. The telescope consists of a matrix of Digital Optical Modules that will detect the Cherenkov light originated by the interaction of the neutrinos in the proximity of the detector. This contribution describes the main components of the read-out electronics of the Digital Optical Module: the Power Board, which delivers all the power supply required by the Digital Optical Molule electronics; the Central Logic Board, the main core of the read-out system, hosting 31 Time to Digital Converters with 1 ns resolution and the White Rabbit protocol embedded in the Central Logic Board Field Programmable Gate Array; the Octopus boards, that transfer the Low Voltage Digital Signals from the PMT bases to the Central Logic Board and finally the PMT bases, in charge of converting the analogue signal produced in the 31 3" PMTs into a Low Voltage Digital Signal.

Temporal analysis of floodwater volumes in New Orleans after Hurricane Katrina: Chapter 3H in Science and the storms-the USGS response to the hurricanes of 2005

USGS Publications Warehouse

Smith, Jodie; Rowland, James

2007-01-01

Satellite images from multiple sensors and dates were analyzed to measure the extent of flooding caused by Hurricane Katrina in the New Orleans, La., area. The flood polygons were combined with a high-resolution digital elevation model to estimate water depths and volumes in designated areas. The multiple satellite acquisitions enabled monitoring of the floodwater volume and extent through time.

An exploration of the accuracy of an invasive method for measuring the volume of specimens of Amoeba proteus.

PubMed

Whalen, T A; Demarco, A J

1999-10-01

A method is described for measuring the volume of individual specimens of Amoeba proteus which utilizes an easily constructed compressor to flatten the specimen to a known thickness. The microscopic image of the flattened specimen is captured on tape, digitized and analysed with the NIH Image software. The results from one specimen are given to illustrate the sources and magnitude of errors affecting these volume measurements.

Use of a turbine in a breath-by-breath computer-based respiratory measurement system.

PubMed

Venkateswaran, R S; Gallagher, R R

1997-01-01

The Computer-Based Respiratory Measurement System (CBRMS) is capable of analyzing individual breaths to monitor the kinetics of oxygen uptake, carbon dioxide production, tidal volumes, pulmonary ventilation, and other respiratory parameters during rest, exercise, and recovery. Respiratory gas volumes are measured by a calibrated turbine transducer while the respiratory gas concentrations are measured by a calibrated, fast-responding medical gas analyzer. To improve accuracy of the results, the inspiratory volumes and gas concentrations are measured and not assumed to be equal to expiratory volumes or ambient concentrations respectively. The respiratory gas volumes and concentration signals are digitized and stored in arrays. The gas volumes are converted to flow signals by software differentiation. These digitized data arrays are stored as files in a personal computer. Time alignment of the flow and gas concentration signals is performed at each breath for maximum accuracy in analysis. For system verification, data were obtained under resting conditions and under constant load exercises at 50 W, 100 W, and 150 W. These workloads were performed by a healthy, male subject on a bicycle ergometer. A strong correlation existed between the CBRMS steady-state results and the standard end-expirate bag collection technique. Thus, there is reason to believe that the CBRMS is capable of calculating respiratory transient responses accurately, a significant contribution to an understanding of total respiratory system function.

Engineering Drawing Practices - Volume I of II: Aerospace and Ground Support Equipment

NASA Technical Reports Server (NTRS)

Schwindt, Paul A.

2015-01-01

This manual establishes the essential requirements and reference documents for the preparation and revision of digital product definition data sets prepared for or by NASA at KSC. This volume is only applicable to KSC in-house programs/projects. These requirements do not apply to the preparation of illustrations, artwork, or figures in technical publications.

Automatic transfer function generation for volume rendering of high-resolution x-ray 3D digital mammography images

NASA Astrophysics Data System (ADS)

Alyassin, Abdal M.

2002-05-01

3D Digital mammography (3DDM) is a new technology that provides high resolution X-ray breast tomographic data. Like any other tomographic medical imaging modalities, viewing a stack of tomographic images may require time especially if the images are of large matrix size. In addition, it may cause difficulty to conceptually construct 3D breast structures. Therefore, there is a need to readily visualize the data in 3D. However, one of the issues that hinder the usage of volume rendering (VR) is finding an automatic way to generate transfer functions that efficiently map the important diagnostic information in the data. We have developed a method that randomly samples the volume. Based on the mean and the standard deviation of these samples, the technique determines the lower limit and upper limit of a piecewise linear ramp transfer function. We have volume rendered several 3DDM data using this technique and compared visually the outcome with the result from a conventional automatic technique. The transfer function generated through the proposed technique provided superior VR images over the conventional technique. Furthermore, the improvement in the reproducibility of the transfer function correlated with the number of samples taken from the volume at the expense of the processing time.

Modeling light

NASA Astrophysics Data System (ADS)

Dawson, P.; Gage, J.; Takatsuka, M.; Goyette, S.

2009-02-01

To compete with other digital images, holograms must go beyond the current range of source-image types, such as sequences of photographs, laser scans, and 3D computer graphics (CG) scenes made with software designed for other applications. This project develops a set of innovative techniques for creating 3D digital content specifically for digital holograms, with virtual tools which enable the direct hand-crafting of subjects, mark by mark, analogous to Michelangelo's practice in drawing, painting and sculpture. The haptic device, the Phantom Premium 1.5 is used to draw against three-dimensional laser- scan templates of Michelangelo's sculpture placed within the holographic viewing volume.

Optimal investments in digital communication systems in primary exchange area

NASA Astrophysics Data System (ADS)

Garcia, R.; Hornung, R.

1980-11-01

Integer linear optimization theory, following Gomory's method, was applied to the model planning of telecommunication networks in which all future investments are made in digital systems only. The integer decision variables are the number of digital systems set up on cable or radiorelay links that can be installed. The objective function is the total cost of the extension of the existing line capacity to meet the demand between primary and local exchanges. Traffic volume constraints and flow conservation in transit nodes complete the model. Results indicating computing time and method efficiency are illustrated by an example.

Development of a high-resolution automatic digital (urine/electrolytes) flow volume and rate measurement system of miniature size

NASA Technical Reports Server (NTRS)

Liu, F. F.

1975-01-01

To aid in the quantitative analysis of man's physiological rhythms, a flowmeter to measure circadian patterns of electrolyte excretion during various environmental stresses was developed. One initial flowmeter was designed and fabricated, the sensor of which is the approximate size of a wristwatch. The detector section includes a special type of dielectric integrating type sensor which automatically controls, activates, and deactivates the flow sensor data output by determining the presence or absence of fluid flow in the system, including operation under zero-G conditions. The detector also provides qualitative data on the composition of the fluid. A compact electronic system was developed to indicate flow rate as well as total volume per release or the cumulative volume of several releases in digital/analog forms suitable for readout or telemetry. A suitable data readout instrument is also provided. Calibration and statistical analyses of the performance functions required of the flowmeter were also conducted.

European Scientific Notes. Volume 36, Number 7,

DTIC Science & Technology

1982-07-31

services digital net- works, lierarhicel processing, of structural information in artificial intelligence. and human-machine interaction and digital...reduction in the rate of in those days were connected by "fossae" or growth and even the initiation of erosion along artificial channels. Thus littoral...fisher- Comacchio (see map) in the eighth century. men who would like to increase it. Additional The present Po delta is artificial in that conflicts

Digital image processing for the earth resources technology satellite data.

NASA Technical Reports Server (NTRS)

Will, P. M.; Bakis, R.; Wesley, M. A.

1972-01-01

This paper discusses the problems of digital processing of the large volumes of multispectral image data that are expected to be received from the ERTS program. Correction of geometric and radiometric distortions are discussed and a byte oriented implementation is proposed. CPU timing estimates are given for a System/360 Model 67, and show that a processing throughput of 1000 image sets per week is feasible.

A digital model for planning water management at Benton Lake National Wildlife Refuge, west-central Montana

USGS Publications Warehouse

Nimick, David A.; McCarthy, Peter M.; Fields, Vanessa

2011-01-01

Benton Lake National Wildlife Refuge is an important area for waterfowl production and migratory stopover in west-central Montana. Eight wetland units covering about 5,600 acres are the essential features of the refuge. Water availability for the wetland units can be uncertain owing to the large natural variations in precipitation and runoff and the high cost of pumping supplemental water. The U.S. Geological Survey, in cooperation with the U.S. Fish and Wildlife Service, has developed a digital model for planning water management. The model can simulate strategies for water transfers among the eight wetland units and account for variability in runoff and pumped water. This report describes this digital model, which uses a water-accounting spreadsheet to track inputs and outputs to each of the wetland units of Benton Lake National Wildlife Refuge. Inputs to the model include (1) monthly values for precipitation, pumped water, runoff, and evaporation; (2) water-level/capacity data for each wetland unit; and (3) the pan-evaporation coefficient. Outputs include monthly water volume and flooded surface area for each unit for as many as 5 consecutive years. The digital model was calibrated by comparing simulated and historical measured water volumes for specific test years.

Cancer information seeking in the digital age: effects of Angelina Jolie's prophylactic mastectomy announcement.

PubMed

Noar, Seth M; Althouse, Benjamin M; Ayers, John W; Francis, Diane B; Ribisl, Kurt M

2015-01-01

. This study used digital surveillance to examine the impact of Angelina Jolie's prophylactic mastectomy announcement on cancer information seeking. . We analyzed 4 categories of breast cancer-related Internet search queries from 2010 to 2013 in the United States. . Compared with the preceding 6 weeks, general information queries were 112% (95% confidence interval [CI], 79-146) higher the day of the announcement and remained 35% (95% CI, 22-49) higher over the week after the editorial. Risk assessment queries were 165% (95% CI, 110-222) higher the day of the announcement and 52% (95% CI, 31-75) higher across the week. Genetics and treatment queries showed little volume before the announcement but increased 2154% (95% CI, 1550-7076) and 9900% (95% CI, 3196-1,064,000) the day of, respectively, and remained higher across the week (812% [95% CI, 402-3913] and 2625% [95% CI, 551-317,000]). All query categories returned to normal volumes by the beginning of the second week. . Jolie's unique announcement spurred significant information seeking about breast cancer genetic testing and treatment procedures, although the surge in queries returned to preannouncement levels after 1 week. Future research should apply digital methods to advance our understanding of cancer information seeking in the digital age. © The Author(s) 2014.

The digital traces of bubbles: feedback cycles between socio-economic signals in the Bitcoin economy.

PubMed

Garcia, David; Tessone, Claudio J; Mavrodiev, Pavlin; Perony, Nicolas

2014-10-06

What is the role of social interactions in the creation of price bubbles? Answering this question requires obtaining collective behavioural traces generated by the activity of a large number of actors. Digital currencies offer a unique possibility to measure socio-economic signals from such digital traces. Here, we focus on Bitcoin, the most popular cryptocurrency. Bitcoin has experienced periods of rapid increase in exchange rates (price) followed by sharp decline; we hypothesize that these fluctuations are largely driven by the interplay between different social phenomena. We thus quantify four socio-economic signals about Bitcoin from large datasets: price on online exchanges, volume of word-of-mouth communication in online social media, volume of information search and user base growth. By using vector autoregression, we identify two positive feedback loops that lead to price bubbles in the absence of exogenous stimuli: one driven by word of mouth, and the other by new Bitcoin adopters. We also observe that spikes in information search, presumably linked to external events, precede drastic price declines. Understanding the interplay between the socio-economic signals we measured can lead to applications beyond cryptocurrencies to other phenomena that leave digital footprints, such as online social network usage. © 2014 The Author(s) Published by the Royal Society. All rights reserved.

The digital traces of bubbles: feedback cycles between socio-economic signals in the Bitcoin economy

PubMed Central

Garcia, David; Tessone, Claudio J.; Mavrodiev, Pavlin; Perony, Nicolas

2014-01-01

What is the role of social interactions in the creation of price bubbles? Answering this question requires obtaining collective behavioural traces generated by the activity of a large number of actors. Digital currencies offer a unique possibility to measure socio-economic signals from such digital traces. Here, we focus on Bitcoin, the most popular cryptocurrency. Bitcoin has experienced periods of rapid increase in exchange rates (price) followed by sharp decline; we hypothesize that these fluctuations are largely driven by the interplay between different social phenomena. We thus quantify four socio-economic signals about Bitcoin from large datasets: price on online exchanges, volume of word-of-mouth communication in online social media, volume of information search and user base growth. By using vector autoregression, we identify two positive feedback loops that lead to price bubbles in the absence of exogenous stimuli: one driven by word of mouth, and the other by new Bitcoin adopters. We also observe that spikes in information search, presumably linked to external events, precede drastic price declines. Understanding the interplay between the socio-economic signals we measured can lead to applications beyond cryptocurrencies to other phenomena that leave digital footprints, such as online social network usage. PMID:25100315

A Medical Image Backup Architecture Based on a NoSQL Database and Cloud Computing Services.

PubMed

Santos Simões de Almeida, Luan Henrique; Costa Oliveira, Marcelo

2015-01-01

The use of digital systems for storing medical images generates a huge volume of data. Digital images are commonly stored and managed on a Picture Archiving and Communication System (PACS), under the DICOM standard. However, PACS is limited because it is strongly dependent on the server's physical space. Alternatively, Cloud Computing arises as an extensive, low cost, and reconfigurable resource. However, medical images contain patient information that can not be made available in a public cloud. Therefore, a mechanism to anonymize these images is needed. This poster presents a solution for this issue by taking digital images from PACS, converting the information contained in each image file to a NoSQL database, and using cloud computing to store digital images.

Effect of data compression on diagnostic accuracy in digital hand and chest radiography

NASA Astrophysics Data System (ADS)

Sayre, James W.; Aberle, Denise R.; Boechat, Maria I.; Hall, Theodore R.; Huang, H. K.; Ho, Bruce K. T.; Kashfian, Payam; Rahbar, Guita

1992-05-01

Image compression is essential to handle a large volume of digital images including CT, MR, CR, and digitized films in a digital radiology operation. The full-frame bit allocation using the cosine transform technique developed during the last few years has been proven to be an excellent irreversible image compression method. This paper describes the effect of using the hardware compression module on diagnostic accuracy in hand radiographs with subperiosteal resorption and chest radiographs with interstitial disease. Receiver operating characteristic analysis using 71 hand radiographs and 52 chest radiographs with five observers each demonstrates that there is no statistical significant difference in diagnostic accuracy between the original films and the compressed images with a compression ratio as high as 20:1.

Examining live cell cultures during apoptosis by digital holographic phase imaging and Raman spectroscopy

NASA Astrophysics Data System (ADS)

Khmaladze, Alexander

2017-11-01

Cellular apoptosis is a unique, organized series of events, leading to programmed cell death. In this work, we present a combined digital holography/Raman spectroscopy technique to study live cell cultures during apoptosis. Digital holographic microscopy measurements of live cell cultures yield information about cell shape and volume, changes to which are indicative of alterations in cell cycle and initiation of cell death mechanisms. Raman spectroscopic measurements provide complementary information about cells, such as protein, lipid and nucleic acid content, and the spectral signatures associated with structural changes in molecules. Our work indicates that the chemical changes in proteins, which were detected by Raman measurements, preceded morphological changes, which were seen with digital holographic microscopy.

PROMIS series. Volume 8: Midlatitude ground magnetograms

NASA Technical Reports Server (NTRS)

Fairfield, D. H.; Russell, C. T.

1990-01-01

This is the eighth in a series of volumes pertaining to the Polar Region Outer Magnetosphere International Study (PROMIS). This volume contains 24 hour stack plots of 1-minute average, H and D component, ground magnetograms for the period March 10 through June 16, 1986. Nine midlatitude ground stations were selected from the UCLA magnetogram data base that was constructed from all available digitized magnetogram stations. The primary purpose of this publication is to allow users to define universal times and onset longitudes of magnetospheric substorms.

Radiation dose and image quality of X-ray volume imaging systems: cone-beam computed tomography, digital subtraction angiography and digital fluoroscopy.

PubMed

Paul, Jijo; Jacobi, Volkmar; Farhang, Mohammad; Bazrafshan, Babak; Vogl, Thomas J; Mbalisike, Emmanuel C

2013-06-01

Radiation dose and image quality estimation of three X-ray volume imaging (XVI) systems. A total of 126 patients were examined using three XVI systems (groups 1-3) and their data were retrospectively analysed from 2007 to 2012. Each group consisted of 42 patients and each patient was examined using cone-beam computed tomography (CBCT), digital subtraction angiography (DSA) and digital fluoroscopy (DF). Dose parameters such as dose-area product (DAP), skin entry dose (SED) and image quality parameters such as Hounsfield unit (HU), noise, signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) were estimated and compared using appropriate statistical tests. Mean DAP and SED were lower in recent XVI than its previous counterparts in CBCT, DSA and DF. HU of all measured locations was non-significant between the groups except the hepatic artery. Noise showed significant difference among groups (P < 0.05). Regarding CNR and SNR, the recent XVI showed a higher and significant difference compared to its previous versions. Qualitatively, CBCT showed significance between versions unlike the DSA and DF which showed non-significance. A reduction of radiation dose was obtained for the recent-generation XVI system in CBCT, DSA and DF. Image noise was significantly lower; SNR and CNR were higher than in previous versions. The technological advancements and the reduction in the number of frames led to a significant dose reduction and improved image quality with the recent-generation XVI system. • X-ray volume imaging (XVI) systems are increasingly used for interventional radiological procedures. • More modern XVI systems use lower radiation doses compared with earlier counterparts. • Furthermore more modern XVI systems provide higher image quality. • Technological advances reduce radiation dose and improve image quality.

A Digital Preclinical PET/MRI Insert and Initial Results.

PubMed

Weissler, Bjoern; Gebhardt, Pierre; Dueppenbecker, Peter M; Wehner, Jakob; Schug, David; Lerche, Christoph W; Goldschmidt, Benjamin; Salomon, Andre; Verel, Iris; Heijman, Edwin; Perkuhn, Michael; Heberling, Dirk; Botnar, Rene M; Kiessling, Fabian; Schulz, Volkmar

2015-11-01

Combining Positron Emission Tomography (PET) with Magnetic Resonance Imaging (MRI) results in a promising hybrid molecular imaging modality as it unifies the high sensitivity of PET for molecular and cellular processes with the functional and anatomical information from MRI. Digital Silicon Photomultipliers (dSiPMs) are the digital evolution in scintillation light detector technology and promise high PET SNR. DSiPMs from Philips Digital Photon Counting (PDPC) were used to develop a preclinical PET/RF gantry with 1-mm scintillation crystal pitch as an insert for clinical MRI scanners. With three exchangeable RF coils, the hybrid field of view has a maximum size of 160 mm × 96.6 mm (transaxial × axial). 0.1 ppm volume-root-mean-square B 0-homogeneity is kept within a spherical diameter of 96 mm (automatic volume shimming). Depending on the coil, MRI SNR is decreased by 13% or 5% by the PET system. PET count rates, energy resolution of 12.6% FWHM, and spatial resolution of 0.73 mm (3) (isometric volume resolution at isocenter) are not affected by applied MRI sequences. PET time resolution of 565 ps (FWHM) degraded by 6 ps during an EPI sequence. Timing-optimized settings yielded 260 ps time resolution. PET and MR images of a hot-rod phantom show no visible differences when the other modality was in operation and both resolve 0.8-mm rods. Versatility of the insert is shown by successfully combining multi-nuclei MRI ((1)H/(19)F) with simultaneously measured PET ((18)F-FDG). A longitudinal study of a tumor-bearing mouse verifies the operability, stability, and in vivo capabilities of the system. Cardiac- and respiratory-gated PET/MRI motion-capturing (CINE) images of the mouse heart demonstrate the advantage of simultaneous acquisition for temporal and spatial image registration.

Reading Out Single-Molecule Digital RNA and DNA Isothermal Amplification in Nanoliter Volumes with Unmodified Camera Phones

PubMed Central

2016-01-01

Digital single-molecule technologies are expanding diagnostic capabilities, enabling the ultrasensitive quantification of targets, such as viral load in HIV and hepatitis C infections, by directly counting single molecules. Replacing fluorescent readout with a robust visual readout that can be captured by any unmodified cell phone camera will facilitate the global distribution of diagnostic tests, including in limited-resource settings where the need is greatest. This paper describes a methodology for developing a visual readout system for digital single-molecule amplification of RNA and DNA by (i) selecting colorimetric amplification-indicator dyes that are compatible with the spectral sensitivity of standard mobile phones, and (ii) identifying an optimal ratiometric image-process for a selected dye to achieve a readout that is robust to lighting conditions and camera hardware and provides unambiguous quantitative results, even for colorblind users. We also include an analysis of the limitations of this methodology, and provide a microfluidic approach that can be applied to expand dynamic range and improve reaction performance, allowing ultrasensitive, quantitative measurements at volumes as low as 5 nL. We validate this methodology using SlipChip-based digital single-molecule isothermal amplification with λDNA as a model and hepatitis C viral RNA as a clinically relevant target. The innovative combination of isothermal amplification chemistry in the presence of a judiciously chosen indicator dye and ratiometric image processing with SlipChip technology allowed the sequence-specific visual readout of single nucleic acid molecules in nanoliter volumes with an unmodified cell phone camera. When paired with devices that integrate sample preparation and nucleic acid amplification, this hardware-agnostic approach will increase the affordability and the distribution of quantitative diagnostic and environmental tests. PMID:26900709

Numerical investigation of the effect of particle concentration on particle measurement by digital holography

NASA Astrophysics Data System (ADS)

Zhao, Huafeng; Zhou, Binwu; Wu, Xuecheng; Wu, Yingchun; Gao, Xiang; Gréhan, Gérard; Cen, Kefa

2014-04-01

Digital holography plays a key role in particle field measurement, and appears to be a strong contender as the next-generation technology for diagnostics of 3D particle field. However, various recording parameters, such as the recording distance, the particle size, the wavelength, the size of the CCD chip, the pixel size and the particle concentration, will affect the results of the reconstruction, and may even determine the success or failure of a measurement. This paper presents a numerical investigation on the effect of particle concentration, the volume depth to evaluate the capability of digital holographic microscopy. Standard particles holograms with all known recording parameters are numerically generated by using a common procedure based on Lorenz-Mie scattering theory. Reconstruction of those holograms are then performed by a wavelet-transform based method. Results show that the reconstruction efficiency decreases quickly until particle concentration reaches 50×104 (mm-3), and decreases linearly with the increase of particle concentration from 50 × 104 (mm-3) to 860 × 104 (mm-3) in the same volume. The first half of the line waves larger than the second half. It also indicates that the increase of concentration leads the rise in average diameter error and z position error of particles. Besides, the volume depth also plays a key role in reconstruction.

Full-field digital mammography image data storage reduction using a crop tool.

PubMed

Kang, Bong Joo; Kim, Sung Hun; An, Yeong Yi; Choi, Byung Gil

2015-05-01

The storage requirements for full-field digital mammography (FFDM) in a picture archiving and communication system are significant, so methods to reduce the data set size are needed. A FFDM crop tool for this purpose was designed, implemented, and tested. A total of 1,651 screening mammography cases with bilateral FFDMs were included in this study. The images were cropped using a DICOM editor while maintaining image quality. The cases were evaluated according to the breast volume (1/4, 2/4, 3/4, and 4/4) in the craniocaudal view. The image sizes between the cropped image group and the uncropped image group were compared. The overall image quality and reader's preference were independently evaluated by the consensus of two radiologists. Digital storage requirements for sets of four uncropped to cropped FFDM images were reduced by 3.8 to 82.9 %. The mean reduction rates according to the 1/4-4/4 breast volumes were 74.7, 61.1, 38, and 24 %, indicating that the lower the breast volume, the smaller the size of the cropped data set. The total image data set size was reduced from 87 to 36.7 GB, or a 57.7 % reduction. The overall image quality and the reader's preference for the cropped images were higher than those of the uncropped images. FFDM mammography data storage requirements can be significantly reduced using a crop tool.

[Diagnostic possibilities of digital volume tomography].

PubMed

Lemkamp, Michael; Filippi, Andreas; Berndt, Dorothea; Lambrecht, J Thomas

2006-01-01

Cone beam computed tomography allows high quality 3D images of cranio-facial structures. Although detail resolution is increased, x-ray exposition is reduced compared to classic computer tomography. The volume is analysed in three orthogonal plains, which can be rotated independently without quality loss. Cone beam computed tomography seems to be a less expensive and less x-ray exposing alternative to classic computer tomography.

Adult Basic Education in the Age of New Literacies. New Literacies and Digital Epistemologies. Volume 42

ERIC Educational Resources Information Center

Jacobson, Erik

2012-01-01

The volume addresses the ways that the field of adult basic education has already been impacted by changes in technology and what needs to happen for learners and teachers to take full advantage of newly developing resources. The analysis is organized around three main themes: Learning, Teaching, and Organizing. Each section reviews relevant…

Epidemiology of digital amputation and replantation in Taiwan: A population-based study.

PubMed

Chang, Dun-Hao; Ye, Shih-Yu; Chien, Li-Chien; Ma, Hsu

2015-10-01

Publications on digital amputation and replantation have been mostly derived from case series in high-volume hand surgery practices, and epidemiological studies are few. This study used a population-based dataset to illustrate the incidence of digital amputation, patient and hospital characteristics, and their relationships with replantation. A claim for reimbursement dataset (2008) was provided as a research database by the Bureau of National Health Insurance, Taiwan. Patients with ICD-9-CM coded as digital amputation (885 and 886) were included. These were cross-referenced with procedure codes for replantation procedures (84.21 and 84.22). We defined the patients who underwent thumb replantation (84.21) and thumb amputation (84.01) during a single hospitalization as replantation failure. Patient and hospital characteristics were studied with statistical analysis. In total, 2358 patients with digital amputation were admitted (1859 male, 499 female), mean age 39.2 ± 15.5 years. The incidence was 10.2/100,000 person-years. The highest incidence was 14.7/100,000 person-years in the age group 45-54 years. Machinery and powered hand tools caused 68.8% of digital amputations. Thumb amputation [odds ratio (OR): 1.35, p = 0.01], private hospital (OR: 1.40, p = 0.01), medical center (OR: 2.38, p < 0.001), regional hospital (OR: 2.41, p < 0.001) and hospitals with an annual volume >20 digital amputations (OR: 4.23, p < 0.001) were associated with higher attempt rates for replantation. Elderly patients (age >65 years) had higher risk of thumb replantation failure (OR: 32.30, p = 0.045), while hospitals with >20 annual replantations had lower risk (OR: 0.11, p = 0.02). Our study of the National Health Insurance database characterized the epidemiology of digital amputation patients undergoing replantation and the facilities in Taiwan where these procedures are performed. The hospitals treating more digital amputation patients had higher attempt rates and lower thumb failure rates. Copyright © 2015. Published by Elsevier Taiwan.

Computer Sciences and Data Systems, volume 2

NASA Technical Reports Server (NTRS)

1987-01-01

Topics addressed include: data storage; information network architecture; VHSIC technology; fiber optics; laser applications; distributed processing; spaceborne optical disk controller; massively parallel processors; and advanced digital SAR processors.

Stereotaxic 18F-FDG PET and MRI templates with three-dimensional digital atlas for statistical parametric mapping analysis of tree shrew brain.

PubMed

Huang, Qi; Nie, Binbin; Ma, Chen; Wang, Jing; Zhang, Tianhao; Duan, Shaofeng; Wu, Shang; Liang, Shengxiang; Li, Panlong; Liu, Hua; Sun, Hua; Zhou, Jiangning; Xu, Lin; Shan, Baoci

2018-01-01

Tree shrews are proposed as an alternative animal model to nonhuman primates due to their close affinity to primates. Neuroimaging techniques are widely used to study brain functions and structures of humans and animals. However, tree shrews are rarely applied in neuroimaging field partly due to the lack of available species specific analysis methods. In this study, 10 PET/CT and 10 MRI images of tree shrew brain were used to construct PET and MRI templates; based on histological atlas we reconstructed a three-dimensional digital atlas with 628 structures delineated; then the digital atlas and templates were aligned into a stereotaxic space. Finally, we integrated the digital atlas and templates into a toolbox for tree shrew brain spatial normalization, statistical analysis and results localization. We validated the feasibility of the toolbox by simulated data with lesions in laterodorsal thalamic nucleus (LD). The lesion volumes of simulated PET and MRI images were (12.97±3.91)mm 3 and (7.04±0.84)mm 3 . Statistical results at p<0.005 showed the lesion volumes of PET and MRI were 13.18mm 3 and 8.06mm 3 in LD. To our knowledge, we report the first PET template and digital atlas of tree shrew brain. Compared to the existing MRI templates, our MRI template was aligned into stereotaxic space. And the toolbox is the first software dedicated for tree shrew brain analysis. The templates and digital atlas of tree shrew brain, as well as the toolbox, facilitate the use of tree shrews in neuroimaging field. Copyright © 2017 Elsevier B.V. All rights reserved.

Design of a fault tolerant airborne digital computer. Volume 2: Computational requirements and technology

NASA Technical Reports Server (NTRS)

Ratner, R. S.; Shapiro, E. B.; Zeidler, H. M.; Wahlstrom, S. E.; Clark, C. B.; Goldberg, J.

1973-01-01

This final report summarizes the work on the design of a fault tolerant digital computer for aircraft. Volume 2 is composed of two parts. Part 1 is concerned with the computational requirements associated with an advanced commercial aircraft. Part 2 reviews the technology that will be available for the implementation of the computer in the 1975-1985 period. With regard to the computation task 26 computations have been categorized according to computational load, memory requirements, criticality, permitted down-time, and the need to save data in order to effect a roll-back. The technology part stresses the impact of large scale integration (LSI) on the realization of logic and memory. Also considered was module interconnection possibilities so as to minimize fault propagation.

Optical computing and neural networks; Proceedings of the Meeting, National Chiao Tung Univ., Hsinchu, Taiwan, Dec. 16, 17, 1992

NASA Technical Reports Server (NTRS)

Hsu, Ken-Yuh (Editor); Liu, Hua-Kuang (Editor)

1992-01-01

The present conference discusses optical neural networks, photorefractive nonlinear optics, optical pattern recognition, digital and analog processors, and holography and its applications. Attention is given to bifurcating optical information processing, neural structures in digital halftoning, an exemplar-based optical neural net classifier for color pattern recognition, volume storage in photorefractive disks, and microlaser-based compact optical neuroprocessors. Also treated are the optical implementation of a feature-enhanced optical interpattern-associative neural network model and its optical implementation, an optical pattern binary dual-rail logic gate module, a theoretical analysis for holographic associative memories, joint transform correlators, image addition and subtraction via the Talbot effect, and optical wavelet-matched filters. (No individual items are abstracted in this volume)

Adaptation of reference volumes for correlation-based digital holographic particle tracking

NASA Astrophysics Data System (ADS)

Hesseling, Christina; Peinke, Joachim; Gülker, Gerd

2018-04-01

Numerically reconstructed reference volumes tailored to particle images are used for particle position detection by means of three-dimensional correlation. After a first tracking of these positions, the experimentally recorded particle images are retrieved as a posteriori knowledge about the particle images in the system. This knowledge is used for a further refinement of the detected positions. A transparent description of the individual algorithm steps including the results retrieved with experimental data complete the paper. The work employs extraordinarily small particles, smaller than the pixel pitch of the camera sensor. It is the first approach known to the authors that combines numerical knowledge about particle images and particle images retrieved from the experimental system to an iterative particle tracking approach for digital holographic particle tracking velocimetry.

Optical computing and neural networks; Proceedings of the Meeting, National Chiao Tung Univ., Hsinchu, Taiwan, Dec. 16, 17, 1992

NASA Astrophysics Data System (ADS)

Hsu, Ken-Yuh; Liu, Hua-Kuang

The present conference discusses optical neural networks, photorefractive nonlinear optics, optical pattern recognition, digital and analog processors, and holography and its applications. Attention is given to bifurcating optical information processing, neural structures in digital halftoning, an exemplar-based optical neural net classifier for color pattern recognition, volume storage in photorefractive disks, and microlaser-based compact optical neuroprocessors. Also treated are the optical implementation of a feature-enhanced optical interpattern-associative neural network model and its optical implementation, an optical pattern binary dual-rail logic gate module, a theoretical analysis for holographic associative memories, joint transform correlators, image addition and subtraction via the Talbot effect, and optical wavelet-matched filters. (No individual items are abstracted in this volume)

Determining physiological cross-sectional area of extensor carpi radialis longus and brevis as a whole and by regions using 3D computer muscle models created from digitized fiber bundle data.

PubMed

Ravichandiran, Kajeandra; Ravichandiran, Mayoorendra; Oliver, Michele L; Singh, Karan S; McKee, Nancy H; Agur, Anne M R

2009-09-01

Architectural parameters and physiological cross-sectional area (PCSA) are important determinants of muscle function. Extensor carpi radialis longus (ECRL) and brevis (ECRB) are used in muscle transfers; however, their regional architectural differences have not been investigated. The aim of this study is to develop computational algorithms to quantify and compare architectural parameters (fiber bundle length, pennation angle, and volume) and PCSA of ECRL and ECRB. Fiber bundles distributed throughout the volume of ECRL (75+/-20) and ECRB (110+/-30) were digitized in eight formalin embalmed cadaveric specimens. The digitized data was reconstructed in Autodesk Maya with computational algorithms implemented in Python. The mean PCSA and fiber bundle length were significantly different between ECRL and ECRB (p < or = 0.05). Superficial ECRL had significantly longer fiber bundle length than the deep region, whereas the PCSA of superficial ECRB was significantly larger than the deep region. The regional quantification of architectural parameters and PCSA provides a framework for the exploration of partial tendon transfers of ECRL and ECRB.

Design of a fault tolerant airborne digital computer. Volume 1: Architecture

NASA Technical Reports Server (NTRS)

Wensley, J. H.; Levitt, K. N.; Green, M. W.; Goldberg, J.; Neumann, P. G.

1973-01-01

This volume is concerned with the architecture of a fault tolerant digital computer for an advanced commercial aircraft. All of the computations of the aircraft, including those presently carried out by analogue techniques, are to be carried out in this digital computer. Among the important qualities of the computer are the following: (1) The capacity is to be matched to the aircraft environment. (2) The reliability is to be selectively matched to the criticality and deadline requirements of each of the computations. (3) The system is to be readily expandable. contractible, and (4) The design is to appropriate to post 1975 technology. Three candidate architectures are discussed and assessed in terms of the above qualities. Of the three candidates, a newly conceived architecture, Software Implemented Fault Tolerance (SIFT), provides the best match to the above qualities. In addition SIFT is particularly simple and believable. The other candidates, Bus Checker System (BUCS), also newly conceived in this project, and the Hopkins multiprocessor are potentially more efficient than SIFT in the use of redundancy, but otherwise are not as attractive.

Interband cascade laser-based ppbv-level mid-infrared methane detection using two digital lock-in amplifier schemes

NASA Astrophysics Data System (ADS)

Song, Fang; Zheng, Chuantao; Yu, Di; Zhou, Yanwen; Yan, Wanhong; Ye, Weilin; Zhang, Yu; Wang, Yiding; Tittel, Frank K.

2018-03-01

A parts-per-billion in volume (ppbv) level mid-infrared methane (CH4) sensor system was demonstrated using second-harmonic wavelength modulation spectroscopy (2 f-WMS). A 3291 nm interband cascade laser (ICL) and a multi-pass gas cell (MPGC) with a 16 m optical path length were adopted in the reported sensor system. Two digital lock-in amplifier (DLIA) schemes, a digital signal processor (DSP)-based DLIA and a LabVIEW-based DLIA, were used for harmonic signal extraction. A limit of detection (LoD) of 13.07 ppbv with an averaging time of 2 s was achieved using the DSP-based DLIA and a LoD of 5.84 ppbv was obtained using the LabVIEW-based DLIA with the same averaging time. A rise time of 0→2 parts-per-million in volume (ppmv) and fall time of 2→0 ppmv were observed. Outdoor atmospheric CH4 concentration measurements were carried out to evaluate the sensor performance using the two DLIA schemes.

Learning To Bridge the Digital Divide: Schooling for Tomorrow. Education and Skills. [National Center on Adult Literacy (NCAL)/Organization for Economic Cooperation and Development (OECD) Roundtable (5th, Philadelphia, Pennsylvania, December 8-10, 1999)].

ERIC Educational Resources Information Center

Jame, Edwyn; Istance, David

This publication builds on the papers and discussions of the Fifth National Center on Adult Literacy (NCAL)/Organization for Economic Cooperation and Development (OECD) Roundtable. The volume presents an analysis of the "learning digital divide" in different countries--developed and developing--and the policies and innovations designed…

CTC Sentinel. Volume 7, Issue 10, October 2014

DTIC Science & Technology

2014-10-01

currencies l ike e-gold, Bitcoin , Peercoin, and Dodgecoin provide complex yet eff icient mechanisms for the transfer of funds, as well as the...that terrorists are considering and, in l imited instances, using digital currencies such as Bitcoin to f inance activit ies. 1 While...to its novelty and partly due to its complexity, the evolving world of digital or crypto currencies like BitCoin and their impact on AML/CFT has

Correlation between carotid bifurcation calcium burden on non-enhanced CT and percentage stenosis, as confirmed by digital subtraction angiography

PubMed Central

Sarikaya, B; Lohman, B; Mckinney, A M; Gadani, S; Irfan, M; Lucato, L

2012-01-01

Objectives Previous evidence supports a direct relationship between the calcium burden (volume) on post-contrast CT with the percent internal carotid artery (ICA) stenosis at the carotid bifurcation. We sought to further investigate this relationship by comparing non-enhanced CT (NECT) and digital subtraction angiography (DSA). Methods 50 patients (aged 41–82 years) were retrospectively identified who had undergone cervical NECT and DSA. A 64-multidetector array CT (MDCT) scanner was utilised and the images reviewed using preset window widths/levels (30/300) optimised to calcium, with the volumes measured via three-dimensional reconstructive software. Stenosis measurements were performed on DSA and luminal diameter stenoses >40% were considered “significant”. Volume thresholds of 0.01, 0.03, 0.06, 0.09 and 0.12 cm3 were utilised and Pearson'S correlation coefficient (r) was calculated to correlate the calcium volume with percent stenosis. Results Of 100 carotid bifurcations, 88 were available and of these 7 were significantly stenotic. The NECT calcium volume moderately correlated with percent stenosis on DSA r=0.53 (p<0.01). A moderate–strong correlation was found between the square root of calcium volume on NECT with percent stenosis on DSA (r=0.60, p<0.01). Via a receiver operating characteristic curve, 0.06 cm3 was determined to be the best threshold (sensitivity 100%, specificity 90.1%, negative predictive value 100% and positive predictive value 46.7%) for detecting significant stenoses. Conclusion This preliminary investigation confirms a correlation between carotid bifurcation calcium volume and percent ICA stenosis and is promising for the optimal threshold for stenosis detection. Future studies could utilise calcium volumes to create a “score” that could predict high grade stenosis. PMID:21896662

Volumetric evolution of Surtsey, Iceland, from topographic maps and scanning airborne laser altimetry

USGS Publications Warehouse

Garvin, J.B.; Williams, R.S.; Frawley, J.J.; Krabill, W.B.

2000-01-01

The volumetric evolution of Surtsey has been estimated on the basis of digital elevation models derived from NASA scanning airborne laser altimeter surveys (20 July 1998), as well as digitized 1:5,000-scale topographic maps produced by the National Land Survey of Iceland and by Norrman. Subaerial volumes have been computed from co-registered digital elevation models (DEM's) from 6 July 1968, 11 July 1975, 16 July 1993, and 20 July 1998 (scanning airborne laser altimetry), as well as true surface area (above mean sea level). Our analysis suggests that the subaerial volume of Surtsey has been reduced from nearly 0.100 km3 on 6 July 1968 to 0.075 km3 on 20 July 1998. Linear regression analysis of the temporal evolution of Surtsey's subaerial volume indicates that most of its subaerial surface will be at or below mean sea-level by approximately 2100. This assumes a conservative estimate of continuation of the current pace of marine erosion and mass-wasting on the island, including the indurated core of the conduits of the Surtur I and Surtur II eruptive vents. If the conduits are relatively resistant to marine erosion they will become sea stacks after the rest of the island has become a submarine shoal, and some portions of the island could survive for centuries. The 20 July 1998 scanning laser altimeter surveys further indicate rapid enlargement of erosional canyons in the northeastern portion of the partial tephra ring associated with Surtur I. Continued airborne and eventually spaceborne topographic surveys of Surtsey are planned to refine the inter-annual change of its subaerial volume.

The Fulldome Curriculum for the Spitz SciDome Digital Planetarium: Volume 2

NASA Astrophysics Data System (ADS)

Bradstreet, David H.; Sanders, S. J.; Huggins, S.

2014-01-01

The Spitz Fulldome Curriculum (FDC) for the SciDome digital planetarium ushered in a new and innovative way to present astronomical pedagogy via its use of the unique teaching attributes of the digital planetarium. In the case of the FDC, which uses the ubiquitous Starry Night planetarium software as its driving engine, these engaging and novel teaching techniques have also been made usable to desktop computers and flat-screen video projectors for classroom use. Volume 2 of the FDC introduces exciting new classes and mini-lessons to further enlighten and invigorate students as they struggle with often difficult three dimensional astronomical concepts. Additionally, other topics with related astronomical ties have been created to integrate history into planetarium presentations. One of the strongest advantages of the SciDome is its use of Starry Night as its astronomical engine. With it students can create their own astronomical configurations in the computer lab or at home, using the PC or Mac version. They can then simply load their creations onto the SciDome planetarium system and display them for their classmates on the dome. This poster will discuss and illustrate some of the new content that has been developed for Volume 2. Topics covered in Volume 2 include eclipses, plotting planet locations on a curtate orbit chart by observing their positions in the sky, time and timekeeping (including sidereal day, hour angles, sidereal time, LAST, LMST, time zones and the International Date Line), teaching to the Boy Scout Merit Badge requirements, plotting scale analemmas on the surface of planets and interpreting them, precession, astronomical events in revolutionary Boston, the Lincoln Almanac Trial, eclipsing binaries, lunar librations, a trip through the universe, watching the speed of light move in real time, stellar sizes and the Milky Way.

Games for learning: vast wasteland or a digital promise?

PubMed

Levine, Michael H; Vaala, Sarah E

2013-01-01

Research about emerging best practices in the learning sciences points to the potential of deploying digital games as one possible solution to the twin challenges of weak student engagement and the need for more robust achievement in literacy, science, technology, and math. This chapter reviews key cross-cutting themes in this special volume, drawing perspective from the context of the current United States program and policy reform. The authors conclude that digital games have some unique potential to address pressing educational challenges, but that new mechanisms for advancing purposeful research and development must be adopted by both policymakers and industry leaders. Copyright © 2013 Wiley Periodicals, Inc., A Wiley Company.

[INVITED] Laser-induced forward transfer: A high resolution additive manufacturing technology

NASA Astrophysics Data System (ADS)

Delaporte, Philippe; Alloncle, Anne-Patricia

2016-04-01

Among the additive manufacturing techniques, laser-induced forward transfer addresses the challenges of printing thin films in solid phase or small volume droplets in liquid phase with very high resolution. This paper reviews the physics of this process and explores the pros and cons of this technology versus other digital printing technologies. The main field of applications are printed electronics, organic electronics and tissue engineering, and the most promising short terms ones concern digital laser printing of sensors and conductive tracks. Future directions and emerging areas of interest are discussed such as printing solid from a liquid phase and 3D digital nanomanufacturing.

NASA/BLM Applications Pilot Test (APT), phase 2. Volume 1: Executive summary. [vegetation mapping and production estimation in northwestern Arizona

NASA Technical Reports Server (NTRS)

1981-01-01

Data from LANDSAT, low altitude color aerial photography, and ground visits were combined and used to produce vegetation cover maps and to estimate productivity of range, woodland, and forest resources in northwestern Arizona. A planning session, two workshops, and four status reviews were held to assist technology transfer from NASA. Computer aided digital classification of LANDSAT data was selected as a major source of input data. An overview is presented of the data processing, data collection, productivity estimation, and map verification techniques used. Cost analysis and digital LANDSAT digital products are also considered.

The Implications of Virtual Machine Introspection for Digital Forensics on Nonquiescent Virtual Machines

DTIC Science & Technology

2011-06-01

metacity [ 2788] gnome-panel [ 2790] nautilus [ 2794] bonobo -activati [ 2797] gnome-vfs-daemo [ 2799] eggcups [ 2800] gnome-volume-ma [ 2809] bt...xrdb [ 2784] metacity [ 2788] gnome-panel [ 2790] nautilus [ 2794] bonobo -activati [ 2797] gnome-vfs-daemo [ 2799] eggcups [ 2800] gnome-volume...gnome-keyring-d [ 2764] gnome-settings- [ 2780] xrdb [ 2784] metacity [ 2788] gnome-panel [ 2790] nautilus [ 2794] bonobo -activati [ 2797] gnome

A highly addressable static droplet array enabling digital control of a single droplet at pico-volume resolution.

PubMed

Jeong, Heon-Ho; Lee, Byungjin; Jin, Si Hyung; Jeong, Seong-Geun; Lee, Chang-Soo

2016-04-26

Droplet-based microfluidics enabling exquisite liquid-handling has been developed for diagnosis, drug discovery and quantitative biology. Compartmentalization of samples into a large number of tiny droplets is a great approach to perform multiplex assays and to improve reliability and accuracy using a limited volume of samples. Despite significant advances in microfluidic technology, individual droplet handling in pico-volume resolution is still a challenge in obtaining more efficient and varying multiplex assays. We present a highly addressable static droplet array (SDA) enabling individual digital manipulation of a single droplet using a microvalve system. In a conventional single-layer microvalve system, the number of microvalves required is dictated by the number of operation objects; thus, individual trap-and-release on a large-scale 2D array format is highly challenging. By integrating double-layer microvalves, we achieve a "balloon" valve that preserves the pressure-on state under released pressure; this valve can allow the selective releasing and trapping of 7200 multiplexed pico-droplets using only 1 μL of sample without volume loss. This selectivity and addressability completely arranged only single-cell encapsulated droplets from a mixture of droplet compositions via repetitive selective trapping and releasing. Thus, it will be useful for efficient handling of miniscule volumes of rare or clinical samples in multiplex or combinatory assays, and the selective collection of samples.

Social signals and algorithmic trading of Bitcoin.

PubMed

Garcia, David; Schweitzer, Frank

2015-09-01

The availability of data on digital traces is growing to unprecedented sizes, but inferring actionable knowledge from large-scale data is far from being trivial. This is especially important for computational finance, where digital traces of human behaviour offer a great potential to drive trading strategies. We contribute to this by providing a consistent approach that integrates various datasources in the design of algorithmic traders. This allows us to derive insights into the principles behind the profitability of our trading strategies. We illustrate our approach through the analysis of Bitcoin, a cryptocurrency known for its large price fluctuations. In our analysis, we include economic signals of volume and price of exchange for USD, adoption of the Bitcoin technology and transaction volume of Bitcoin. We add social signals related to information search, word of mouth volume, emotional valence and opinion polarization as expressed in tweets related to Bitcoin for more than 3 years. Our analysis reveals that increases in opinion polarization and exchange volume precede rising Bitcoin prices, and that emotional valence precedes opinion polarization and rising exchange volumes. We apply these insights to design algorithmic trading strategies for Bitcoin, reaching very high profits in less than a year. We verify this high profitability with robust statistical methods that take into account risk and trading costs, confirming the long-standing hypothesis that trading-based social media sentiment has the potential to yield positive returns on investment.

Social signals and algorithmic trading of Bitcoin

PubMed Central

Garcia, David; Schweitzer, Frank

2015-01-01

The availability of data on digital traces is growing to unprecedented sizes, but inferring actionable knowledge from large-scale data is far from being trivial. This is especially important for computational finance, where digital traces of human behaviour offer a great potential to drive trading strategies. We contribute to this by providing a consistent approach that integrates various datasources in the design of algorithmic traders. This allows us to derive insights into the principles behind the profitability of our trading strategies. We illustrate our approach through the analysis of Bitcoin, a cryptocurrency known for its large price fluctuations. In our analysis, we include economic signals of volume and price of exchange for USD, adoption of the Bitcoin technology and transaction volume of Bitcoin. We add social signals related to information search, word of mouth volume, emotional valence and opinion polarization as expressed in tweets related to Bitcoin for more than 3 years. Our analysis reveals that increases in opinion polarization and exchange volume precede rising Bitcoin prices, and that emotional valence precedes opinion polarization and rising exchange volumes. We apply these insights to design algorithmic trading strategies for Bitcoin, reaching very high profits in less than a year. We verify this high profitability with robust statistical methods that take into account risk and trading costs, confirming the long-standing hypothesis that trading-based social media sentiment has the potential to yield positive returns on investment. PMID:26473051

Empirical model for the volume-change behavior of debris flows

USGS Publications Warehouse

Cannon, S.H.; ,

1993-01-01

The potential travel down hillsides; movement stops where the volume-change behavior of flows as they travel down hillsides ; movement stops where the volume of actively flowing debris becomes negligible. The average change in volume over distance for 26 recent debris flows in the Honolulu area was assumed to be a function of the slope over which the debris flow traveled, the degree of flow confinement by the channel, and an assigned value for the type of vegetation through which the debris flow traveled. Analysis of the data yielded a relation that can be incorporated into digital elevation models to characterize debris-flow travel on Oahu.

Left ventricular pressure and volume data acquisition and analysis using LabVIEW.

PubMed

Cassidy, S C; Teitel, D F

1997-03-01

To automate analysis of left ventricular pressure-volume data, we used LabVIEW to create applications that digitize and display data recorded from conductance and manometric catheters. Applications separate data into cardiac cycles, calculate parallel conductance, and calculate indices of left ventricular function, including end-systolic elastance, preload-recruitable stroke work, stroke volume, ejection fraction, stroke work, maximum and minimum derivative of ventricular pressure, heart rate, indices of relaxation, peak filling rate, and ventricular chamber stiffness. Pressure-volume loops can be graphically displayed. These analyses are exported to a text-file. These applications have simplified and automated the process of evaluating ventricular function.

Digital Rock Physics Aplications: Visualisation Complex Pore and Porosity-Permeability Estimations of the Porous Sandstone Reservoir

NASA Astrophysics Data System (ADS)

Handoyo; Fatkhan; Del, Fourier

2018-03-01

Reservoir rock containing oil and gas generally has high porosity and permeability. High porosity is expected to accommodate hydrocarbon fluid in large quantities and high permeability is associated with the rock’s ability to let hydrocarbon fluid flow optimally. Porosity and permeability measurement of a rock sample is usually performed in the laboratory. We estimate the porosity and permeability of sandstones digitally by using digital images from μCT-Scan. Advantages of the method are non-destructive and can be applied for small rock pieces also easily to construct the model. The porosity values are calculated by comparing the digital image of the pore volume to the total volume of the sandstones; while the permeability values are calculated using the Lattice Boltzmann calculations utilizing the nature of the law of conservation of mass and conservation of momentum of a particle. To determine variations of the porosity and permeability, the main sandstone samples with a dimension of 300 × 300 × 300 pixels are made into eight sub-cubes with a size of 150 × 150 × 150 pixels. Results of digital image modeling fluid flow velocity are visualized as normal velocity (streamline). Variations in value sandstone porosity vary between 0.30 to 0.38 and permeability variations in the range of 4000 mD to 6200 mD. The results of calculations show that the sandstone sample in this research is highly porous and permeable. The method combined with rock physics can be powerful tools for determining rock properties from small rock fragments.

MAGIC Computer Simulation. Volume 1: User Manual

DTIC Science & Technology

1970-07-01

vulnerability and MAGIC programs. A three-digit code is assigned to each component of the target, such as armor, gun tube; and a two-digit code is assigned to...A review of the subject Magic Computer Simulation User and Analyst Manuals has been conducted based upon a request received from the US Army...1970 4. TITLE AND SUBTITLE MAGIC Computer Simulation 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT

From the sample preparation to the volume rendering images of small animals: A step by step example of a procedure to carry out the micro-CT study of the leafhopper insect Homalodisca vitripennis (Hemiptera: Cicadellidae)

USDA-ARS?s Scientific Manuscript database

Advances in micro-CT, digital computed tomography (CT) scan uses X-rays to make detailed pictures of structures inside of the body. Combining micro-CT with Digital Video Library systems, and linking this to Big Data, will change the way researchers, entomologist, and the public search and use anato...

Spatiotemporal Visualization of Time-Series Satellite-Derived CO2 Flux Data Using Volume Rendering and Gpu-Based Interpolation on a Cloud-Driven Digital Earth

NASA Astrophysics Data System (ADS)

Wu, S.; Yan, Y.; Du, Z.; Zhang, F.; Liu, R.

2017-10-01

The ocean carbon cycle has a significant influence on global climate, and is commonly evaluated using time-series satellite-derived CO2 flux data. Location-aware and globe-based visualization is an important technique for analyzing and presenting the evolution of climate change. To achieve realistic simulation of the spatiotemporal dynamics of ocean carbon, a cloud-driven digital earth platform is developed to support the interactive analysis and display of multi-geospatial data, and an original visualization method based on our digital earth is proposed to demonstrate the spatiotemporal variations of carbon sinks and sources using time-series satellite data. Specifically, a volume rendering technique using half-angle slicing and particle system is implemented to dynamically display the released or absorbed CO2 gas. To enable location-aware visualization within the virtual globe, we present a 3D particlemapping algorithm to render particle-slicing textures onto geospace. In addition, a GPU-based interpolation framework using CUDA during real-time rendering is designed to obtain smooth effects in both spatial and temporal dimensions. To demonstrate the capabilities of the proposed method, a series of satellite data is applied to simulate the air-sea carbon cycle in the China Sea. The results show that the suggested strategies provide realistic simulation effects and acceptable interactive performance on the digital earth.

The study on changes of rectum area in proton prostate cancer therapy

NASA Astrophysics Data System (ADS)

Kim, S. Y.; Lee, H. K.; Shin, H. W.; Kim, S. C.; Cho, J. H.

2015-10-01

The purpose of this study is to determine the changes in the rectum area during treatment and to identify the rectum area within the given field of view in order to reproduce the same pose as that presented during therapy planning to properly deliver the planned dose to the prostate. We obtained digitally reconstructed radiographs after planning treatment for 30 patients out of all patients who had been subjected to proton prostate cancer therapy from August 2012 to November 2014 at this hospital. We then obtained an image using a digital imaging positioning system (DIPS) on the first day of treatment. When planning the digitally reconstructed radiograph treatment, we determined the change in size of the rectum between the actual treatment and treatment planning by measuring the cross section of the rectum and the cross section on the image from the DIPS. The results indicated that the rectum area in the digitally reconstructed radiograph taken during treatment planning and the rectum area obtained from the DIPS image during treatment were different. As a consequence, when region targeted for proton treatment of prostate cancer does not maintain a constant volume, the position of the prostate does not receive an adequate dose due to such changes. Therefore, the results of this study will be useful to determine the corresponding volume during a prostate treatment plan.

Automatic cell identification and visualization using digital holographic microscopy with head mounted augmented reality devices.

PubMed

O'Connor, Timothy; Rawat, Siddharth; Markman, Adam; Javidi, Bahram

2018-03-01

We propose a compact imaging system that integrates an augmented reality head mounted device with digital holographic microscopy for automated cell identification and visualization. A shearing interferometer is used to produce holograms of biological cells, which are recorded using customized smart glasses containing an external camera. After image acquisition, segmentation is performed to isolate regions of interest containing biological cells in the field-of-view, followed by digital reconstruction of the cells, which is used to generate a three-dimensional (3D) pseudocolor optical path length profile. Morphological features are extracted from the cell's optical path length map, including mean optical path length, coefficient of variation, optical volume, projected area, projected area to optical volume ratio, cell skewness, and cell kurtosis. Classification is performed using the random forest classifier, support vector machines, and K-nearest neighbor, and the results are compared. Finally, the augmented reality device displays the cell's pseudocolor 3D rendering of its optical path length profile, extracted features, and the identified cell's type or class. The proposed system could allow a healthcare worker to quickly visualize cells using augmented reality smart glasses and extract the relevant information for rapid diagnosis. To the best of our knowledge, this is the first report on the integration of digital holographic microscopy with augmented reality devices for automated cell identification and visualization.

Quality assurance in the EORTC 22033-26033/CE5 phase III randomized trial for low grade glioma: the digital individual case review.

PubMed

Fairchild, Alysa; Weber, Damien C; Bar-Deroma, Raquel; Gulyban, Akos; Fenton, Paul A; Stupp, Roger; Baumert, Brigitta G

2012-06-01

The phase III EORTC 22033-26033/NCIC CE5 intergroup trial compares 50.4 Gy radiotherapy with up-front temozolomide in previously untreated low-grade glioma. We describe the digital EORTC individual case review (ICR) performed to evaluate protocol radiotherapy (RT) compliance. Fifty-eight institutions were asked to submit 1-2 randomly selected cases. Digital ICR datasets were uploaded to the EORTC server and accessed by three central reviewers. Twenty-seven parameters were analysed including volume delineation, treatment planning, organ at risk (OAR) dosimetry and verification. Consensus reviews were collated and summary statistics calculated. Fifty-seven of seventy-two requested datasets from forty-eight institutions were technically usable. 31/57 received a major deviation for at least one section. Relocation accuracy was according to protocol in 45. Just over 30% had acceptable target volumes. OAR contours were missing in an average of 25% of cases. Up to one-third of those present were incorrectly drawn while dosimetry was largely protocol compliant. Beam energy was acceptable in 97% and 48 patients had per protocol beam arrangements. Digital RT plan submission and review within the EORTC 22033-26033 ICR provide a solid foundation for future quality assurance procedures. Strict evaluation resulted in overall grades of minor and major deviation for 37% and 32%, respectively. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

Thermal error analysis and compensation for digital image/volume correlation

NASA Astrophysics Data System (ADS)

Pan, Bing

2018-02-01

Digital image/volume correlation (DIC/DVC) rely on the digital images acquired by digital cameras and x-ray CT scanners to extract the motion and deformation of test samples. Regrettably, these imaging devices are unstable optical systems, whose imaging geometry may undergo unavoidable slight and continual changes due to self-heating effect or ambient temperature variations. Changes in imaging geometry lead to both shift and expansion in the recorded 2D or 3D images, and finally manifest as systematic displacement and strain errors in DIC/DVC measurements. Since measurement accuracy is always the most important requirement in various experimental mechanics applications, these thermal-induced errors (referred to as thermal errors) should be given serious consideration in order to achieve high accuracy, reproducible DIC/DVC measurements. In this work, theoretical analyses are first given to understand the origin of thermal errors. Then real experiments are conducted to quantify thermal errors. Three solutions are suggested to mitigate or correct thermal errors. Among these solutions, a reference sample compensation approach is highly recommended because of its easy implementation, high accuracy and in-situ error correction capability. Most of the work has appeared in our previously published papers, thus its originality is not claimed. Instead, this paper aims to give a comprehensive overview and more insights of our work on thermal error analysis and compensation for DIC/DVC measurements.

Industrial applications study. Volume V. Bibliography of relevant literature. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Brown, Harry L.; Hamel, Bernard B.; Karamchetty, Som

1976-12-01

This five-volume report represents an initial Phase O evaluation of waste heat recovery and utilization potential in the manufacturing portion of the industrial sector. The scope of this initial phase was limited to the two-digit SIC level and addressed the feasibility of obtaining in-depth energy information in the industrial sector. Within this phase, a successful methodology and approaches for data gathering and assessment are established. Using these approaches, energy use and waste heat profiles were developed at the 2-digit level; with this data, waste heat utilization technologies were evaluated. The first section of the bibliography lists extensive citations for allmore » industries. The next section is composed of an extensive literature search with abstracts for industrial energy conservation. EPA publications on specific industries and general references conclude the publication. (MCW)« less

Three-dimensional digital holographic aperture synthesis for rapid and highly-accurate large-volume metrology

NASA Astrophysics Data System (ADS)

Crouch, Stephen; Kaylor, Brant M.; Barber, Zeb W.; Reibel, Randy R.

2015-09-01

Currently large volume, high accuracy three-dimensional (3D) metrology is dominated by laser trackers, which typically utilize a laser scanner and cooperative reflector to estimate points on a given surface. The dependency upon the placement of cooperative targets dramatically inhibits the speed at which metrology can be conducted. To increase speed, laser scanners or structured illumination systems can be used directly on the surface of interest. Both approaches are restricted in their axial and lateral resolution at longer stand-off distances due to the diffraction limit of the optics used. Holographic aperture ladar (HAL) and synthetic aperture ladar (SAL) can enhance the lateral resolution of an imaging system by synthesizing much larger apertures by digitally combining measurements from multiple smaller apertures. Both of these approaches only produce two-dimensional imagery and are therefore not suitable for large volume 3D metrology. We combined the SAL and HAL approaches to create a swept frequency digital holographic 3D imaging system that provides rapid measurement speed for surface coverage with unprecedented axial and lateral resolution at longer standoff ranges. The technique yields a "data cube" of Fourier domain data, which can be processed with a 3D Fourier transform to reveal a 3D estimate of the surface. In this paper, we provide the theoretical background for the technique and show experimental results based on an ultra-wideband frequency modulated continuous wave (FMCW) chirped heterodyne ranging system showing ~100 micron lateral and axial precisions at >2 m standoff distances.

Apparatus Tests Peeling Of Bonded Rubbery Material

NASA Technical Reports Server (NTRS)

Crook, Russell A.; Graham, Robert

1996-01-01

Instrumented hydraulic constrained blister-peel apparatus obtains data on degree of bonding between specimen of rubbery material and rigid plate. Growth of blister tracked by video camera, digital clock, pressure transducer, and piston-displacement sensor. Cylinder pressure controlled by hydraulic actuator system. Linear variable-differential transformer (LVDT) and float provide second, independent measure of change in blister volume used as more precise volume feedback in low-growth-rate test.

A method for volume determination of the orbit and its contents by high resolution axial tomography and quantitative digital image analysis.

PubMed Central

Cooper, W C

1985-01-01

The various congenital and acquired conditions which alter orbital volume are reviewed. Previous investigative work to determine orbital capacity is summarized. Since these studies were confined to postmortem evaluations, the need for a technique to measure orbital volume in the living state is presented. A method for volume determination of the orbit and its contents by high-resolution axial tomography and quantitative digital image analysis is reported. This procedure has proven to be accurate (the discrepancy between direct and computed measurements ranged from 0.2% to 4%) and reproducible (greater than 98%). The application of this method to representative clinical problems is presented and discussed. The establishment of a diagnostic system versatile enough to expand the usefulness of computerized axial tomography and polytomography should add a new dimension to ophthalmic investigation and treatment. Images FIGURE 8 FIGURE 9 FIGURE 10 A FIGURE 10 B FIGURE 11 A FIGURE 11 B FIGURE 12 FIGURE 13 FIGURE 14 FIGURE 15 FIGURE 16 FIGURE 17 FIGURE 18 FIGURE 19 FIGURE 20 FIGURE 21 FIGURE 22 FIGURE 23 FIGURE 24 FIGURE 25 FIGURE 26 A FIGURE 26 B FIGURE 27 FIGURE 28 FIGURE 29 FIGURE 30 FIGURE 31 FIGURE 32 PMID:3938582

Uncertainty modelling and analysis of volume calculations based on a regular grid digital elevation model (DEM)

NASA Astrophysics Data System (ADS)

Li, Chang; Wang, Qing; Shi, Wenzhong; Zhao, Sisi

2018-05-01

The accuracy of earthwork calculations that compute terrain volume is critical to digital terrain analysis (DTA). The uncertainties in volume calculations (VCs) based on a DEM are primarily related to three factors: 1) model error (ME), which is caused by an adopted algorithm for a VC model, 2) discrete error (DE), which is usually caused by DEM resolution and terrain complexity, and 3) propagation error (PE), which is caused by the variables' error. Based on these factors, the uncertainty modelling and analysis of VCs based on a regular grid DEM are investigated in this paper. Especially, how to quantify the uncertainty of VCs is proposed by a confidence interval based on truncation error (TE). In the experiments, the trapezoidal double rule (TDR) and Simpson's double rule (SDR) were used to calculate volume, where the TE is the major ME, and six simulated regular grid DEMs with different terrain complexity and resolution (i.e. DE) were generated by a Gauss synthetic surface to easily obtain the theoretical true value and eliminate the interference of data errors. For PE, Monte-Carlo simulation techniques and spatial autocorrelation were used to represent DEM uncertainty. This study can enrich uncertainty modelling and analysis-related theories of geographic information science.

Estimating Mixed Broadleaves Forest Stand Volume Using Dsm Extracted from Digital Aerial Images

NASA Astrophysics Data System (ADS)

Sohrabi, H.

2012-07-01

In mixed old growth broadleaves of Hyrcanian forests, it is difficult to estimate stand volume at plot level by remotely sensed data while LiDar data is absent. In this paper, a new approach has been proposed and tested for estimating stand forest volume. The approach is based on this idea that forest volume can be estimated by variation of trees height at plots. In the other word, the more the height variation in plot, the more the stand volume would be expected. For testing this idea, 120 circular 0.1 ha sample plots with systematic random design has been collected in Tonekaon forest located in Hyrcanian zone. Digital surface model (DSM) measure the height values of the first surface on the ground including terrain features, trees, building etc, which provides a topographic model of the earth's surface. The DSMs have been extracted automatically from aerial UltraCamD images so that ground pixel size for extracted DSM varied from 1 to 10 m size by 1m span. DSMs were checked manually for probable errors. Corresponded to ground samples, standard deviation and range of DSM pixels have been calculated. For modeling, non-linear regression method was used. The results showed that standard deviation of plot pixels with 5 m resolution was the most appropriate data for modeling. Relative bias and RMSE of estimation was 5.8 and 49.8 percent, respectively. Comparing to other approaches for estimating stand volume based on passive remote sensing data in mixed broadleaves forests, these results are more encouraging. One big problem in this method occurs when trees canopy cover is totally closed. In this situation, the standard deviation of height is low while stand volume is high. In future studies, applying forest stratification could be studied.

Use of MRI for volume estimation of tibialis posterior and plantar intrinsic foot muscles in healthy and chronic plantar fasciitis limbs.

PubMed

Chang, Ryan; Kent-Braun, Jane A; Hamill, Joseph

2012-06-01

Due to complexity of the plantar intrinsic foot muscles, little is known about their muscle architecture in vivo. Chronic plantar fasciitis may be accompanied by muscle atrophy of plantar intrinsic foot muscles and tibialis posterior compromising the dynamic support of the foot prolonging the injury. Magnetic resonance images of the foot may be digitized to quantify muscle architecture. The first purpose of this study was to estimate in vivo the volume and distribution of healthy plantar intrinsic foot muscles. The second purpose was to determine whether chronic plantar fasciitis is accompanied by atrophy of plantar intrinsic foot muscles and tibialis posterior. Magnetic resonance images were taken bilaterally in eight subjects with unilateral plantar fasciitis. Muscle perimeters were digitally outlined and muscle signal intensity thresholds were determined for each image for volume computation. The mean volume of contractile tissue in healthy plantar intrinsic foot muscles was 113.3 cm(3). Forefoot volumes of plantar fasciitis plantar intrinsic foot muscles were 5.2% smaller than healthy feet (P=0.03, ES=0.26), but rearfoot (P=0.26, ES=0.08) and total foot volumes (P=0.07) were similar. No differences were observed in tibialis posterior size. While the total volume of plantar intrinsic foot muscles was similar in healthy and plantar fasciitis feet, atrophy of the forefoot plantar intrinsic foot muscles may contribute to plantar fasciitis by destabilizing the medial longitudinal arch. These results suggest that magnetic resonance imaging measures may be useful in understanding the etiology and rehabilitation of chronic plantar fasciitis. Copyright © 2011 Elsevier Ltd. All rights reserved.

An accuracy aware low power wireless EEG unit with information content based adaptive data compression.

PubMed

Tolbert, Jeremy R; Kabali, Pratik; Brar, Simeranjit; Mukhopadhyay, Saibal

2009-01-01

We present a digital system for adaptive data compression for low power wireless transmission of Electroencephalography (EEG) data. The proposed system acts as a base-band processor between the EEG analog-to-digital front-end and RF transceiver. It performs a real-time accuracy energy trade-off for multi-channel EEG signal transmission by controlling the volume of transmitted data. We propose a multi-core digital signal processor for on-chip processing of EEG signals, to detect signal information of each channel and perform real-time adaptive compression. Our analysis shows that the proposed approach can provide significant savings in transmitter power with minimal impact on the overall signal accuracy.

Comparative data compression techniques and multi-compression results

NASA Astrophysics Data System (ADS)

Hasan, M. R.; Ibrahimy, M. I.; Motakabber, S. M. A.; Ferdaus, M. M.; Khan, M. N. H.

2013-12-01

Data compression is very necessary in business data processing, because of the cost savings that it offers and the large volume of data manipulated in many business applications. It is a method or system for transmitting a digital image (i.e., an array of pixels) from a digital data source to a digital data receiver. More the size of the data be smaller, it provides better transmission speed and saves time. In this communication, we always want to transmit data efficiently and noise freely. This paper will provide some compression techniques for lossless text type data compression and comparative result of multiple and single compression, that will help to find out better compression output and to develop compression algorithms.

Single stock dynamics on high-frequency data: from a compressed coding perspective.

PubMed

Fushing, Hsieh; Chen, Shu-Chun; Hwang, Chii-Ruey

2014-01-01

High-frequency return, trading volume and transaction number are digitally coded via a nonparametric computing algorithm, called hierarchical factor segmentation (HFS), and then are coupled together to reveal a single stock dynamics without global state-space structural assumptions. The base-8 digital coding sequence, which is capable of revealing contrasting aggregation against sparsity of extreme events, is further compressed into a shortened sequence of state transitions. This compressed digital code sequence vividly demonstrates that the aggregation of large absolute returns is the primary driving force for stimulating both the aggregations of large trading volumes and transaction numbers. The state of system-wise synchrony is manifested with very frequent recurrence in the stock dynamics. And this data-driven dynamic mechanism is seen to correspondingly vary as the global market transiting in and out of contraction-expansion cycles. These results not only elaborate the stock dynamics of interest to a fuller extent, but also contradict some classical theories in finance. Overall this version of stock dynamics is potentially more coherent and realistic, especially when the current financial market is increasingly powered by high-frequency trading via computer algorithms, rather than by individual investors.

Single Stock Dynamics on High-Frequency Data: From a Compressed Coding Perspective

PubMed Central

Fushing, Hsieh; Chen, Shu-Chun; Hwang, Chii-Ruey

2014-01-01

High-frequency return, trading volume and transaction number are digitally coded via a nonparametric computing algorithm, called hierarchical factor segmentation (HFS), and then are coupled together to reveal a single stock dynamics without global state-space structural assumptions. The base-8 digital coding sequence, which is capable of revealing contrasting aggregation against sparsity of extreme events, is further compressed into a shortened sequence of state transitions. This compressed digital code sequence vividly demonstrates that the aggregation of large absolute returns is the primary driving force for stimulating both the aggregations of large trading volumes and transaction numbers. The state of system-wise synchrony is manifested with very frequent recurrence in the stock dynamics. And this data-driven dynamic mechanism is seen to correspondingly vary as the global market transiting in and out of contraction-expansion cycles. These results not only elaborate the stock dynamics of interest to a fuller extent, but also contradict some classical theories in finance. Overall this version of stock dynamics is potentially more coherent and realistic, especially when the current financial market is increasingly powered by high-frequency trading via computer algorithms, rather than by individual investors. PMID:24586235

Planar digital nanoliter dispensing system based on thermocapillary actuation.

PubMed

Darhuber, Anton A; Valentino, Joseph P; Troian, Sandra M

2010-04-21

We provide guidelines for the design and operation of a planar digital nanodispensing system based on thermocapillary actuation. Thin metallic microheaters embedded within a chemically patterned glass substrate are electronically activated to generate and control 2D surface temperature distributions which either arrest or trigger liquid flow and droplet formation on demand. This flow control is a consequence of the variation of a liquid's surface tension with temperature, which is used to draw liquid toward cooler regions of the supporting substrate. A liquid sample consisting of several microliters is placed on a flat rectangular supply cell defined by chemical patterning. Thermocapillary switches are then activated to extract a slender fluid filament from the cell and to divide the filament into an array of droplets whose position and volume are digitally controlled. Experimental results for the power required to extract a filament and to divide it into two or more droplets as a function of geometric and operating parameters are in excellent agreement with hydrodynamic simulations. The capability to dispense ultralow volumes onto a 2D substrate extends the functionality of microfluidic devices based on thermocapillary actuation previously shown effective in routing and mixing nanoliter liquid samples on glass or silicon substrates.

Spatial resolution and measurement uncertainty of strains in bone and bone-cement interface using digital volume correlation.

PubMed

Zhu, Ming-Liang; Zhang, Qing-Hang; Lupton, Colin; Tong, Jie

2016-04-01

The measurement uncertainty of strains has been assessed in a bone analogue (sawbone), bovine trabecular bone and bone-cement interface specimens under zero load using the Digital Volume Correlation (DVC) method. The effects of sub-volume size, sample constraint and preload on the measured strain uncertainty have been examined. There is generally a trade-off between the measurement uncertainty and the spatial resolution. Suitable sub-volume sizes have been be selected based on a compromise between the measurement uncertainty and the spatial resolution of the cases considered. A ratio of sub-volume size to a microstructure characteristic (Tb.Sp) was introduced to reflect a suitable spatial resolution, and the measurement uncertainty associated was assessed. Specifically, ratios between 1.6 and 4 appear to give rise to standard deviations in the measured strains between 166 and 620 με in all the cases considered, which would seem to suffice for strain analysis in pre as well as post yield loading regimes. A microscale finite element (μFE) model was built from the CT images of the sawbone, and the results from the μFE model and a continuum FE model were compared with those from the DVC. The strain results were found to differ significantly between the two methods at tissue level, consistent in trend with the results found in human bones, indicating mainly a limitation of the current DVC method in mapping strains at this level. Copyright © 2015 Elsevier Ltd. All rights reserved.

Surface area and volume determination of subgingival calculus using laser fluorescence.

PubMed

Shakibaie, Fardad; Walsh, Laurence J

2014-03-01

Visible red (655 nm) laser fluorescence (LF) devices are currently used for identifying deposits of subgingival calculus on the root surfaces of teeth during dental examination and treatment; however, it is not known how the fluorescence readings produced by commercially available LF systems correlate to the nature of the deposits. This laboratory study explored the correlation between LF digital readings and the surface area and volume of subgingival calculus deposits on teeth. A collection of 30 extracted human posterior teeth with various levels of subgingival deposits of calculus across 240 sites were used in a clinical simulation, with silicone impression material used to replicate periodontal soft tissues. The teeth were scored by two examiners by using three commercial LF systems (DIAGNOdent, DIAGNOdent Pen and KEY3). The silicone was removed, and the teeth were removed for photography at × 20 magnification under white or ultraviolet light. The surface area, thickness, and volume were calculated, and both linear least squares regression and nonlinear (Spearman's rank method) correlation coefficients were determined. Visible red LF digital readings showed better correlation to calculus volume than to surface area. Overall, the best performance was found for the KEY3 system (Spearman coefficient 0.59), compared to the Classic DIAGNOdent (0.56) and the DIAGNOdent Pen (0.49). These results indicate that while visible red LF systems vary somewhat in performance, their LF readings provide a useful estimation of the volume of subgingival calculus deposits present on teeth.

Computerized Dead-Space Volume Measurement of Face Masks Applied to Simulated Faces.

PubMed

Amirav, Israel; Luder, Anthony S; Halamish, Asaf; Marzuk, Chatib; Daitzchman, Marcelo; Newhouse, Michael T

2015-09-01

The dead-space volume (VD) of face masks for metered-dose inhaler treatments is particularly important in infants and young children with asthma, who have relatively low tidal volumes. Data about VD have been traditionally obtained from water displacement measurements, in which masks are held against a flat surface. Because, in real life, masks are placed against the face, VD is likely to differ considerably between masks depending upon their contour and fit. The aim of this study was to develop an accurate and reliable way to measure VD electronically and to apply this technique by comparing the electronic VD of commonly available face masks. Average digital faces were obtained from 3-dimensional images of 270 infants and children. Commonly used face masks (small and medium) from various manufacturers (Monaghan Medical, Pari Respiratory Equipment, Philips Respironics, and InspiRx) were scanned and digitized by means of computed tomography. Each mask was electronically applied to its respective digital face, and the VD enclosed (mL) was computerized and precisely measured. VD varied between 22.6 mL (SootherMask, InspiRx) and 43.1 mL (Vortex, Pari) for small masks and between 41.7 mL (SootherMask) and 71.5 mL (AeroChamber, Monaghan Medical) for medium masks. These values were significantly lower and less variable than measurements obtained by water displacement. Computerized techniques provide an innovative and relatively simple way of accurately measuring the VD of face masks applied to digital faces. As determined by computerized measurement using average-size virtual faces, the InspiRx masks had a significantly smaller VD for both small and medium masks compared with the other masks. This is of considerable importance with respect to aerosol dose and delivery time, particularly in young children. (ClinicalTrials.gov registration NCT01274299.). Copyright © 2015 by Daedalus Enterprises.

Improved Visualization of Intracranial Vessels with Intraoperative Coregistration of Rotational Digital Subtraction Angiography and Intraoperative 3D Ultrasound

PubMed Central

Podlesek, Dino; Meyer, Tobias; Morgenstern, Ute; Schackert, Gabriele; Kirsch, Matthias

2015-01-01

Introduction Ultrasound can visualize and update the vessel status in real time during cerebral vascular surgery. We studied the depiction of parent vessels and aneurysms with a high-resolution 3D intraoperative ultrasound imaging system during aneurysm clipping using rotational digital subtraction angiography as a reference. Methods We analyzed 3D intraoperative ultrasound in 39 patients with cerebral aneurysms to visualize the aneurysm intraoperatively and the nearby vascular tree before and after clipping. Simultaneous coregistration of preoperative subtraction angiography data with 3D intraoperative ultrasound was performed to verify the anatomical assignment. Results Intraoperative ultrasound detected 35 of 43 aneurysms (81%) in 39 patients. Thirty-nine intraoperative ultrasound measurements were matched with rotational digital subtraction angiography and were successfully reconstructed during the procedure. In 7 patients, the aneurysm was partially visualized by 3D-ioUS or was not in field of view. Post-clipping intraoperative ultrasound was obtained in 26 and successfully reconstructed in 18 patients (69%) despite clip related artefacts. The overlap between 3D-ioUS aneurysm volume and preoperative rDSA aneurysm volume resulted in a mean accuracy of 0.71 (Dice coefficient). Conclusions Intraoperative coregistration of 3D intraoperative ultrasound data with preoperative rotational digital subtraction angiography is possible with high accuracy. It allows the immediate visualization of vessels beyond the microscopic field, as well as parallel assessment of blood velocity, aneurysm and vascular tree configuration. Although spatial resolution is lower than for standard angiography, the method provides an excellent vascular overview, advantageous interpretation of 3D-ioUS and immediate intraoperative feedback of the vascular status. A prerequisite for understanding vascular intraoperative ultrasound is image quality and a successful match with preoperative rotational digital subtraction angiography. PMID:25803318

Screening Mammography and Digital Breast Tomosynthesis: Utilization Updates.

PubMed

Boroumand, Gilda; Teberian, Ida; Parker, Laurence; Rao, Vijay M; Levin, David C

2018-05-01

There have been many recent developments in breast imaging, including the 2009 revision of the U.S. Preventive Services Task Force's breast cancer screening guidelines and the approval of digital breast tomosynthesis (DBT) for clinical use in 2011. The objective of this study is to evaluate screening mammography utilization trends among the Medicare population from 2005 to 2015 and examine the volume of DBT studies performed in 2015, the first year for which procedural billing codes for DBT are available. We reviewed national Medicare Part B Physician/Supplier Procedure Summary master files from 2005 to 2015, to determine the annual utilization rate of screening mammography on the basis of procedure codes used for film-screen and digital screening mammography. We also used the Physician/Supplier Procedure Summary master files to determine the volume of screening and diagnostic DBT studies performed in 2015. The utilization rate of screening mammography per 1000 women in the Medicare fee-for-service population increased gradually every year, from 311.5 examinations in 2005 to a peak of 322.9 examinations in 2009, representing a compound annual growth rate of 0.9%. In 2010, the utilization rate abruptly decreased by 4.3% to 309.2 examinations, and it has not since recovered to pre-2010 levels. In 2015, 18.9% of screening and 16.2% of diagnostic digital mammography examinations included DBT as an add-on procedure. In contrast to the annual increase in screening mammography utilization from 2005 to 2009, an abrupt sustained decline in screening occurred beginning in 2010, coinciding with the release of U.S. Preventive Services Task Force recommendations. DBT utilization was somewhat limited in 2015, occurring in conjunction with less than 20% of digital mammography examinations.

Improved visualization of intracranial vessels with intraoperative coregistration of rotational digital subtraction angiography and intraoperative 3D ultrasound.

PubMed

Podlesek, Dino; Meyer, Tobias; Morgenstern, Ute; Schackert, Gabriele; Kirsch, Matthias

2015-01-01

Ultrasound can visualize and update the vessel status in real time during cerebral vascular surgery. We studied the depiction of parent vessels and aneurysms with a high-resolution 3D intraoperative ultrasound imaging system during aneurysm clipping using rotational digital subtraction angiography as a reference. We analyzed 3D intraoperative ultrasound in 39 patients with cerebral aneurysms to visualize the aneurysm intraoperatively and the nearby vascular tree before and after clipping. Simultaneous coregistration of preoperative subtraction angiography data with 3D intraoperative ultrasound was performed to verify the anatomical assignment. Intraoperative ultrasound detected 35 of 43 aneurysms (81%) in 39 patients. Thirty-nine intraoperative ultrasound measurements were matched with rotational digital subtraction angiography and were successfully reconstructed during the procedure. In 7 patients, the aneurysm was partially visualized by 3D-ioUS or was not in field of view. Post-clipping intraoperative ultrasound was obtained in 26 and successfully reconstructed in 18 patients (69%) despite clip related artefacts. The overlap between 3D-ioUS aneurysm volume and preoperative rDSA aneurysm volume resulted in a mean accuracy of 0.71 (Dice coefficient). Intraoperative coregistration of 3D intraoperative ultrasound data with preoperative rotational digital subtraction angiography is possible with high accuracy. It allows the immediate visualization of vessels beyond the microscopic field, as well as parallel assessment of blood velocity, aneurysm and vascular tree configuration. Although spatial resolution is lower than for standard angiography, the method provides an excellent vascular overview, advantageous interpretation of 3D-ioUS and immediate intraoperative feedback of the vascular status. A prerequisite for understanding vascular intraoperative ultrasound is image quality and a successful match with preoperative rotational digital subtraction angiography.

Information management advanced development. Volume 1: Summary

NASA Technical Reports Server (NTRS)

Gerber, C. R.

1972-01-01

The information management systems designed for the modular space station are discussed. Subjects presented are: (1) communications terminal breadboard configuration, (2) digital data bus breadboard configuration, (3) data processing assembly definition, and (4) computer program (software) assembly definition.

Data volume reduction for imaging radar polarimetry

NASA Technical Reports Server (NTRS)

Zebker, Howard A. (Inventor); Held, Daniel N. (Inventor); Vanzyl, Jakob J. (Inventor); Dubois, Pascale C. (Inventor); Norikane, Lynne (Inventor)

1988-01-01

Two alternative methods are presented for digital reduction of synthetic aperture multipolarized radar data using scattering matrices, or using Stokes matrices, of four consecutive along-track pixels to produce averaged data for generating a synthetic polarization image.

Data volume reduction for imaging radar polarimetry

NASA Technical Reports Server (NTRS)

Zebker, Howard A. (Inventor); Held, Daniel N. (Inventor); van Zul, Jakob J. (Inventor); Dubois, Pascale C. (Inventor); Norikane, Lynne (Inventor)

1989-01-01

Two alternative methods are disclosed for digital reduction of synthetic aperture multipolarized radar data using scattering matrices, or using Stokes matrices, of four consecutive along-track pixels to produce averaged data for generating a synthetic polarization image.

MRI for transformation of preserved organs and their pathologies into digital formats for medical education and creation of a virtual pathology museum. A pilot study.

PubMed

Venkatesh, S K; Wang, G; Seet, J E; Teo, L L S; Chong, V F H

2013-03-01

To evaluate the feasibility of magnetic resonance imaging (MRI) for the transformation of preserved organs and their disease entities into digital formats for medical education and creation of a virtual museum. MRI of selected 114 pathology specimen jars representing different organs and their diseases was performed using a 3 T MRI machine with two or more MRI sequences including three-dimensional (3D) T1-weighted (T1W), 3D-T2W, 3D-FLAIR (fluid attenuated inversion recovery), fat-water separation (DIXON), and gradient-recalled echo (GRE) sequences. Qualitative assessment of MRI for depiction of disease and internal anatomy was performed. Volume rendering was performed on commercially available workstations. The digital images, 3D models, and photographs of specimens were archived into a workstation serving as a virtual pathology museum. MRI was successfully performed on all specimens. The 3D-T1W and 3D-T2W sequences demonstrated the best contrast between normal and pathological tissues. The digital material is a useful aid for understanding disease by giving insights into internal structural changes not apparent on visual inspection alone. Volume rendering produced vivid 3D models with better contrast between normal tissue and diseased tissue compared to real specimens or their photographs in some cases. The digital library provides good illustration material for radiological-pathological correlation by enhancing pathological anatomy and information on nature and signal characteristics of tissues. In some specimens, the MRI appearance may be different from corresponding organ and disease in vivo due to dead tissue and changes induced by prolonged contact with preservative fluid. MRI of pathology specimens is feasible and provides excellent images for education and creating a virtual pathology museum that can serve as permanent record of digital material for self-directed learning, improving teaching aids, and radiological-pathological correlation. Copyright © 2012 The Royal College of Radiologists. Published by Elsevier Ltd. All rights reserved.

Sloan Digital Sky Survey III photometric quasar clustering: Probing the initial conditions of the Universe

DOE PAGES

Ho, Shirley; Agarwal, Nishant; Myers, Adam D.; ...

2015-05-22

Here, the Sloan Digital Sky Survey has surveyed 14,555 square degrees of the sky, and delivered over a trillion pixels of imaging data. We present the large-scale clustering of 1.6 million quasars between z=0.5 and z=2.5 that have been classified from this imaging, representing the highest density of quasars ever studied for clustering measurements. This data set spans 0~ 11,00 square degrees and probes a volume of 80 h –3 Gpc 3. In principle, such a large volume and medium density of tracers should facilitate high-precision cosmological constraints. We measure the angular clustering of photometrically classified quasars using an optimalmore » quadratic estimator in four redshift slices with an accuracy of ~ 25% over a bin width of δ l ~ 10–15 on scales corresponding to matter-radiation equality and larger (0ℓ ~ 2–3).« less

Functional specialisation of pelvic limb anatomy in horses (Equus caballus)

PubMed Central

Payne, RC; Hutchinson, JR; Robilliard, JJ; Smith, NC; Wilson, AM

2005-01-01

We provide quantitative anatomical data on the muscle–tendon units of the equine pelvic limb. Specifically, we recorded muscle mass, fascicle length, pennation angle, tendon mass and tendon rest length. Physiological cross sectional area was then determined and maximum isometric force estimated. There was proximal-to-distal reduction in muscle volume and fascicle length. Proximal limb tendons were few and, where present, were relatively short. By contrast, distal limb tendons were numerous and long in comparison to mean muscle fascicle length, increasing potential for elastic energy storage. When compared with published data on thoracic limb muscles, proximal pelvic limb muscles were larger in volume and had shorter fascicles. Distal limb muscle architecture was similar in thoracic and pelvic limbs with the exception of flexor digitorum lateralis (lateral head of the deep digital flexor), the architecture of which was similar to that of the pelvic and thoracic limb superficial digital flexors, suggesting a functional similarity. PMID:15960766

PuMA: the Porous Microstructure Analysis software

NASA Astrophysics Data System (ADS)

Ferguson, Joseph C.; Panerai, Francesco; Borner, Arnaud; Mansour, Nagi N.

2018-01-01

The Porous Microstructure Analysis (PuMA) software has been developed in order to compute effective material properties and perform material response simulations on digitized microstructures of porous media. PuMA is able to import digital three-dimensional images obtained from X-ray microtomography or to generate artificial microstructures. PuMA also provides a module for interactive 3D visualizations. Version 2.1 includes modules to compute porosity, volume fractions, and surface area. Two finite difference Laplace solvers have been implemented to compute the continuum tortuosity factor, effective thermal conductivity, and effective electrical conductivity. A random method has been developed to compute tortuosity factors from the continuum to rarefied regimes. Representative elementary volume analysis can be performed on each property. The software also includes a time-dependent, particle-based model for the oxidation of fibrous materials. PuMA was developed for Linux operating systems and is available as a NASA software under a US & Foreign release.

The field becomes the laboratory? The impact of the contextual digital footprint on the discipline of E/HF.

PubMed

Sharples, Sarah; Houghton, Robert J

2017-02-01

The increasing prevalence of affordable digital sensors, ubiquitous networking and computation puts us at what is only the start of a new era in terms of the volume, coverage and granularity of data that we can access about individuals and workplaces. This paper examines the consequences of harnessing this data deluge for the practice of E/HF. Focusing on what we term the 'contextual digital footprint', the trail of data we produce through interactions with many different digital systems over the course of even a single day, we describe three example scenarios (drawn from health care, distributed work and transportation) and examine how access to data directly drawn in considerable volume from the field will potentially change our application of design and evaluation methods. We conclude with a discussion of issues relevant to ethical and professional practice within this new environment including the increased challenges of respecting anonymity, working with n = all data-sets and the central role of ergonomists in promulgating positive uses of data while retaining a systems-based humanistic approach to work design. Practitioner summary: The paper envisions the impact of new and emerging sources of data about people and workplaces upon future practice in E/HF. We identify practical consequences for ergonomics practice, highlight new areas of professional competence likely to be required and flag both the risks and benefits of adopting a more data-driven approach.

TouchTerrain: A simple web-tool for creating 3D-printable topographic models

NASA Astrophysics Data System (ADS)

Hasiuk, Franciszek J.; Harding, Chris; Renner, Alex Raymond; Winer, Eliot

2017-12-01

An open-source web-application, TouchTerrain, was developed to simplify the production of 3D-printable terrain models. Direct Digital Manufacturing (DDM) using 3D Printers can change how geoscientists, students, and stakeholders interact with 3D data, with the potential to improve geoscience communication and environmental literacy. No other manufacturing technology can convert digital data into tangible objects quickly at relatively low cost; however, the expertise necessary to produce a 3D-printed terrain model can be a substantial burden: knowledge of geographical information systems, computer aided design (CAD) software, and 3D printers may all be required. Furthermore, printing models larger than the build volume of a 3D printer can pose further technical hurdles. The TouchTerrain web-application simplifies DDM for elevation data by generating digital 3D models customized for a specific 3D printer's capabilities. The only required user input is the selection of a region-of-interest using the provided web-application with a Google Maps-style interface. Publically available digital elevation data is processed via the Google Earth Engine API. To allow the manufacture of 3D terrain models larger than a 3D printer's build volume the selected area can be split into multiple tiles without third-party software. This application significantly reduces the time and effort required for a non-expert like an educator to obtain 3D terrain models for use in class. The web application is deployed at http://touchterrain.geol.iastate.edu/.

The thermoregulatory function of the human hand: How do palm and digit proportions affect heat loss?

PubMed

Payne, Stephanie; Macintosh, Alison; Stock, Jay

2018-03-30

The current study assessed whether ecogeographical patterns seen in hand proportions correlate with heat loss directly. Using a brief severe cold immersion experiment on the hand, the influence of hand and digit dimensions on heat loss was evaluated. A sample of 113 living individuals were tested. Two-dimensional and three-dimensional scanning techniques were used to assess hand and digit dimensions. Thermal imaging analysis was used to quantify heat loss during a 3-min ice-water immersion of the hands. When body size was accounted for, hand width and digit length relative to total hand length were significant predictors of heat loss from the hand. The current study provides empirical evidence to support the link between thermodynamic principles relating to surface area-to-volume ratio, and ecogeographical patterns associated with temperature. © 2018 Wiley Periodicals, Inc.

Virtual Field Reconnaissance to enable multi-site collaboration in geoscience fieldwork in Chile.

NASA Astrophysics Data System (ADS)

Hughes, Leanne; Bateson, Luke; Ford, Jonathan; Napier, Bruce; Creixell, Christian; Contreras, Juan-Pablo; Vallette, Jane

2017-04-01

The unique challenges of geological mapping in remote terrains can make cross-organisation collaboration challenging. Cooperation between the British and Chilean Geological Surveys and the Chilean national mining company used the BGS digital Mapping Workflow and virtual field reconnaissance software (GeoVisionary) to undertake geological mapping in a complex area of Andean Geology. The international team undertook a pre-field evaluation using GeoVisionary to integrate massive volumes of data and interpret high resolution satellite imagery, terrain models and existing geological information to capture, manipulate and understand geological features and re-interpret existing maps. This digital interpretation was then taken into the field and verified using the BGS digital data capture system (SIGMA.mobile). This allowed the production of final geological interpretation and creation of a geological map. This presentation describes the digital mapping workflow used in Chile and highlights the key advantages of increased efficiency and communication to colleagues, stakeholders and funding bodies.

ICC '86; Proceedings of the International Conference on Communications, Toronto, Canada, June 22-25, 1986, Conference Record. Volumes 1, 2, & 3

NASA Astrophysics Data System (ADS)

Papers are presented on ISDN, mobile radio systems and techniques for digital connectivity, centralized and distributed algorithms in computer networks, communications networks, quality assurance and impact on cost, adaptive filters in communications, the spread spectrum, signal processing, video communication techniques, and digital satellite services. Topics discussed include performance evaluation issues for integrated protocols, packet network operations, the computer network theory and multiple-access, microwave single sideband systems, switching architectures, fiber optic systems, wireless local communications, modulation, coding, and synchronization, remote switching, software quality, transmission, and expert systems in network operations. Consideration is given to wide area networks, image and speech processing, office communications application protocols, multimedia systems, customer-controlled network operations, digital radio systems, channel modeling and signal processing in digital communications, earth station/on-board modems, computer communications system performance evaluation, source encoding, compression, and quantization, and adaptive communications systems.

3D measurements of live cells via digital holographic microscopy and terahertz spectroscopy

NASA Astrophysics Data System (ADS)

Park, Jun Yong; Oser, Dorian; Iapozzuto, Peter; Norbury, Sean; Mahajan, Supriya; Khmaladze, Alexander; Sharikova, Anna

2016-03-01

This is a study of the central nervous system (CNS) cells, including brain micro vascular endothelial cells (BMV) that constitute the blood brain barrier, and C6 glial cells that are the predominant cell in the brain. The cells are exposed to various chemicals by non-invasive, label-free methods. Digital holographic microscopy (DHM) is a technique that records an interference pattern between an object and reference waves, so that the computationally reconstructed holographic image contains both amplitude and phase information, and 3D images are obtained. The measurement of cell cultures by digital holographic microscopy yields information about cell death mechanisms, since these processes are correlated with individual cell volume. Our in-house DHM combines a visible (red) laser source with a conventional microscope base, and LabVIEW-run data processing. Terahertz spectral signatures are associated with structural changes in molecules and provide complementary information about cells. Both CNS cells BMV and C6 cells are treated with the drug "Methamphetamine" (METH), which induces apoptosis in neuronal cells and exhibits decrease in cell volume, a characteristic of cells undergoing apoptosis (induced cell death). METH can cause CNS cell death by cross-talk between mitochondria-, endoplasmic reticulum-, and receptor-mediated apoptotic events, all of which results in drug induced changes in neuroplasticity and significant neuropathology. Doxorubicin (DOX), a popular anticancer drug, is used as a control. We observe that METH treatment resulted in more pronounced cell volume shrinkage in both the BMV and C6 cells, as compared to DOX-induced cell apoptosis.

Microstructural consequences of blast lung injury characterised with digital volume correlation

NASA Astrophysics Data System (ADS)

Arora, Hari; Nila, Alex; Vitharana, Kalpani; Sherwood, Joseph M.; Nguyen, Thuy-Tien N.; Karunaratne, Angelo; Mohammed, Idris K.; Bodey, Andrew J.; Hellyer, Peter J.; Overby, Darryl R.; Schroter, Robert C.; Hollis, Dave

2017-12-01

This study focuses on microstructural changes that occur within the mammalian lung when subject to blast and how these changes influence strain distributions within the tissue. Shock tube experiments were performed to generate the blast injured specimens (cadaveric Sprague-Dawley rats). Blast overpressures of 100 kPa and 180 kPa were studied. Synchrotron tomography imaging was used to capture volumetric image data of lungs. Specimens were ventilated using a custom-built system to study multiple inflation pressures during each tomography scan. This data enabled the first digital volume correlation (DVC) measurements in lung tissue to be performed. Quantitative analysis was performed to describe the damaged architecture of the lung. No clear changes in the microstructure of the tissue morphology were observed due to controlled low to moderate level blast exposure. However, significant focal sites of injury were observed using DVC, which allowed detection of bias and concentration in the patterns of strain level. Morphological analysis corroborated the findings, illustrating that the focal damage caused by a blast can give rise to diffuse influence across the tissue. It is important to characterise the non-instantly fatal doses of blast, given the transient nature of blast lung in the clinical setting. This research has highlighted the need for better understanding of focal injury and its zone of influence (alveolar inter-dependency and neighbouring tissue burden as a result of focal injury). Digital volume correlation techniques show great promise as a tool to advance this endeavour, providing a new perspective on lung mechanics post-blast.

Driver performance measurement and analysis system (DPMAS). Volume 1, Description and operations manual

DOT National Transportation Integrated Search

1976-08-01

A prototype driver performance measurement and analysis system (DPMAS) has been developed for the National Highway Traffic Safety Administration (NHTSA). This system includes a completely instrumented 1974 Chevrolet Impala capable of digitally record...

A study of data coding technology developments in the 1980-1985 time frame, volume 2

NASA Technical Reports Server (NTRS)

Ingels, F. M.; Shahsavari, M. M.

1978-01-01

The source parameters of digitized analog data are discussed. Different data compression schemes are outlined and analysis of their implementation are presented. Finally, bandwidth compression techniques are given for video signals.

Evaluation of smart video for transit event detection : final report.

DOT National Transportation Integrated Search

2009-06-01

Transit agencies are increasingly using video cameras to fight crime and terrorism. As the volume of video data increases, the existing digital video surveillance systems provide the infrastructure only to capture, store and distribute video, while l...

Quantification of Fibrosis and Osteosclerosis in Myeloproliferative Neoplasms: A Computer-Assisted Image Study

PubMed Central

Teman, Carolin J.; Wilson, Andrew R.; Perkins, Sherrie L.; Hickman, Kimberly; Prchal, Josef T.; Salama, Mohamed E.

2010-01-01

Evaluation of bone marrow fibrosis and osteosclerosis in myeloproliferative neoplasms (MPN) is subject to interobserver inconsistency. Performance data for currently utilized fibrosis grading systems are lacking, and classification scales for osteosclerosis do not exist. Digital imaging can serve as a quantification method for fibrosis and osteosclerosis. We used digital imaging techniques for trabecular area assessment and reticulin-fiber quantification. Patients with all Philadelphia negative MPN subtypes had higher trabecular volume than controls (p ≤0.0015). Results suggest that the degree of osteosclerosis helps differentiate primary myelofibrosis from other MPN. Numerical quantification of fibrosis highly correlated with subjective scores, and interobserver correlation was satisfactory. Digital imaging provides accurate quantification for osteosclerosis and fibrosis. PMID:20122729

Digital Photonic Production of Micro Structures in Glass by In-Volume Selective Laser-Induced Etching using a High Speed Micro Scanner

NASA Astrophysics Data System (ADS)

Gottmann, Jens; Hermans, Martin; Ortmann, Jürgen

Digital photonic production of 3D microfluidic devices and assembled micro mechanics inside fused silica glass is carried out using ISLE directly from digital CAD data. To exploit the potential productivity of new high average power fs-lasers >150 W a modular high speed scanning system has been developed. Acousto-optical beam deflection, galvo-scanners and translation stages are controlled by CAM software. Using a lens with 10 mm focal length a focus radius of 1 μm is scanned with a velocity of 12 m/s on 400 μm track radius enabling the up-scaling of the ISLE- process using fs-laser radiation with up to 30 W.

Change in residual limb size over time in the NU-FlexSIV socket: A case study.

PubMed

Fatone, Stefania; Yohay, Jessica; Caldwell, Ryan

2018-05-01

This case study represented a unique opportunity wherein a long-time user of sub-ischial sockets had kept nearly every socket he wore for a decade. This individual let us borrow these sockets so we could digitize them and indirectly assess change in residual limb size over time by calculating changes in socket volume and circumferences over time. Case Description and Methods: Over a decade, the subject maintained a relatively stable body weight of 84-88 kg and received nine sub-ischial sockets. The internal surface of each socket was scanned using a mechanical digitizer and volume and circumferences calculated. Findings and Outcomes: Socket volume increased 31.3%, from a low of 2659.2 cm 3 for the oldest socket to a high of 3490.6 cm 3 for the most recent socket. Proximal circumferences increased more than distal circumferences with a 15.9% total increase proximally versus 8.9% total increase distally. The results suggest that this individual's residual limb increased in size over time despite the compressive effect of the socket and liner. In addition, the increase in circumference was greater proximally than distally, which is where the remaining muscle bellies are located. Clinical relevance This case study provides insight into the long-term effect of the sub-ischial socket on residual limb volume given compression of the soft tissues by the socket system.

Population of 224 realistic human subject-based computational breast phantoms

DOE Office of Scientific and Technical Information (OSTI.GOV)

Erickson, David W.; Wells, Jered R., E-mail: jered.wells@duke.edu; Sturgeon, Gregory M.

Purpose: To create a database of highly realistic and anatomically variable 3D virtual breast phantoms based on dedicated breast computed tomography (bCT) data. Methods: A tissue classification and segmentation algorithm was used to create realistic and detailed 3D computational breast phantoms based on 230 + dedicated bCT datasets from normal human subjects. The breast volume was identified using a coarse three-class fuzzy C-means segmentation algorithm which accounted for and removed motion blur at the breast periphery. Noise in the bCT data was reduced through application of a postreconstruction 3D bilateral filter. A 3D adipose nonuniformity (bias field) correction was thenmore » applied followed by glandular segmentation using a 3D bias-corrected fuzzy C-means algorithm. Multiple tissue classes were defined including skin, adipose, and several fractional glandular densities. Following segmentation, a skin mask was produced which preserved the interdigitated skin, adipose, and glandular boundaries of the skin interior. Finally, surface modeling was used to produce digital phantoms with methods complementary to the XCAT suite of digital human phantoms. Results: After rejecting some datasets due to artifacts, 224 virtual breast phantoms were created which emulate the complex breast parenchyma of actual human subjects. The volume breast density (with skin) ranged from 5.5% to 66.3% with a mean value of 25.3% ± 13.2%. Breast volumes ranged from 25.0 to 2099.6 ml with a mean value of 716.3 ± 386.5 ml. Three breast phantoms were selected for imaging with digital compression (using finite element modeling) and simple ray-tracing, and the results show promise in their potential to produce realistic simulated mammograms. Conclusions: This work provides a new population of 224 breast phantoms based on in vivo bCT data for imaging research. Compared to previous studies based on only a few prototype cases, this dataset provides a rich source of new cases spanning a wide range of breast types, volumes, densities, and parenchymal patterns.« less

Population of 224 realistic human subject-based computational breast phantoms

PubMed Central

Erickson, David W.; Wells, Jered R.; Sturgeon, Gregory M.; Dobbins, James T.; Segars, W. Paul; Lo, Joseph Y.

2016-01-01

Purpose: To create a database of highly realistic and anatomically variable 3D virtual breast phantoms based on dedicated breast computed tomography (bCT) data. Methods: A tissue classification and segmentation algorithm was used to create realistic and detailed 3D computational breast phantoms based on 230 + dedicated bCT datasets from normal human subjects. The breast volume was identified using a coarse three-class fuzzy C-means segmentation algorithm which accounted for and removed motion blur at the breast periphery. Noise in the bCT data was reduced through application of a postreconstruction 3D bilateral filter. A 3D adipose nonuniformity (bias field) correction was then applied followed by glandular segmentation using a 3D bias-corrected fuzzy C-means algorithm. Multiple tissue classes were defined including skin, adipose, and several fractional glandular densities. Following segmentation, a skin mask was produced which preserved the interdigitated skin, adipose, and glandular boundaries of the skin interior. Finally, surface modeling was used to produce digital phantoms with methods complementary to the XCAT suite of digital human phantoms. Results: After rejecting some datasets due to artifacts, 224 virtual breast phantoms were created which emulate the complex breast parenchyma of actual human subjects. The volume breast density (with skin) ranged from 5.5% to 66.3% with a mean value of 25.3% ± 13.2%. Breast volumes ranged from 25.0 to 2099.6 ml with a mean value of 716.3 ± 386.5 ml. Three breast phantoms were selected for imaging with digital compression (using finite element modeling) and simple ray-tracing, and the results show promise in their potential to produce realistic simulated mammograms. Conclusions: This work provides a new population of 224 breast phantoms based on in vivo bCT data for imaging research. Compared to previous studies based on only a few prototype cases, this dataset provides a rich source of new cases spanning a wide range of breast types, volumes, densities, and parenchymal patterns. PMID:26745896

All-electronic droplet generation on-chip with real-time feedback control for EWOD digital microfluidics.

PubMed

Gong, Jian; Kim, Chang-Jin C J

2008-06-01

Electrowetting-on-dielectric (EWOD) actuation enables digital (or droplet) microfluidics where small packets of liquids are manipulated on a two-dimensional surface. Due to its mechanical simplicity and low energy consumption, EWOD holds particular promise for portable systems. To improve volume precision of the droplets, which is desired for quantitative applications such as biochemical assays, existing practices would require near-perfect device fabrication and operation conditions unless the droplets are generated under feedback control by an extra pump setup off of the chip. In this paper, we develop an all-electronic (i.e., no ancillary pumping) real-time feedback control of on-chip droplet generation. A fast voltage modulation, capacitance sensing, and discrete-time PID feedback controller are integrated on the operating electronic board. A significant improvement is obtained in the droplet volume uniformity, compared with an open loop control as well as the previous feedback control employing an external pump. Furthermore, this new capability empowers users to prescribe the droplet volume even below the previously considered minimum, allowing, for example, 1 : x (x < 1) mixing, in comparison to the previously considered n : m mixing (i.e., n and m unit droplets).

Fit of lithium disilicate crowns fabricated from conventional and digital impressions assessed with micro-CT.

PubMed

Kim, Jae-Hyun; Jeong, Ji-Hye; Lee, Jin-Han; Cho, Hye-Won

2016-10-01

Although the number of lithium disilicate crowns fabricated with computer-aided design and computer-aided manufacturing (CAD-CAM) technology has increased, the accuracy of the prostheses produced by using digital pathways remains unknown. The purpose of this in vitro study was to compare marginal and internal discrepancies of lithium disilicate crowns fabricated from digital and conventional impressions. A typodont mandibular first molar was prepared for a lithium disilicate crown, and 20 duplicate dies were fabricated by milling poly(methyl methacrylate) resin blocks from laboratory scans. Four groups of 5 lithium disilicate crowns each were created by using a CS3500 (Carestream Dental) intraoral digital impression; Trios (3shape) intraoral digital impression; Ceramill Map400 (Amann Girrbach) extraoral digital impression; and a heat-press technique as a control group. All of the IPS e.max CAD (Ivoclar Vivadent AG) crowns were produced using a 5-axis milling engine (Ceramill Motion2). The lithium disilicate crowns were cemented with zinc phosphate cement under finger pressure. Marginal and internal discrepancies were measured using micro-computed tomography (SkyScan1172). One-way ANOVAs with the Tukey honest significant differences test were used for statistical analysis of the data (α=.05). The mean marginal discrepancies of CS3500 lithium disilicate crowns were 129.6 μm, 200.9 μm for Ceramill Map400, and 207.8 μm 176.1 μm for the heat-press technique; and the internal discrepancy volumes for CS3500 were 25.3 mm 3 , 40.7 mm 3 for Trios, 29.1 mm 3 for Ceramill Map400, and 29.1 and 31.4 mm 3 for the heat-press technique. The CS3500 group showed a significantly better marginal discrepancy than the other 3 groups and a smaller internal discrepancy volume than the Trios group (P<.05). Significant differences were found between IPS e.max CAD crowns produced using 2 intraoral digital impressions, whereas no differences were found between IPS e.max CAD crowns produced from an extraoral digital impression and IPS e.max Press crowns produced using a heat-press technique. Copyright © 2016 Editorial Council for the Journal of Prosthetic Dentistry. Published by Elsevier Inc. All rights reserved.

Digital Assays Part I: Partitioning Statistics and Digital PCR.

PubMed

Basu, Amar S

2017-08-01

A digital assay is one in which the sample is partitioned into many small containers such that each partition contains a discrete number of biological entities (0, 1, 2, 3, …). A powerful technique in the biologist's toolkit, digital assays bring a new level of precision in quantifying nucleic acids, measuring proteins and their enzymatic activity, and probing single-cell genotypes and phenotypes. Part I of this review begins with the benefits and Poisson statistics of partitioning, including sources of error. The remainder focuses on digital PCR (dPCR) for quantification of nucleic acids. We discuss five commercial instruments that partition samples into physically isolated chambers (cdPCR) or droplet emulsions (ddPCR). We compare the strengths of dPCR (absolute quantitation, precision, and ability to detect rare or mutant targets) with those of its predecessor, quantitative real-time PCR (dynamic range, larger sample volumes, and throughput). Lastly, we describe several promising applications of dPCR, including copy number variation, quantitation of circulating tumor DNA and viral load, RNA/miRNA quantitation with reverse transcription dPCR, and library preparation for next-generation sequencing. This review is intended to give a broad perspective to scientists interested in adopting digital assays into their workflows. Part II focuses on digital protein and cell assays.

Maximizing the Impact of Digital Media Campaigns to Promote Smoking Cessation: A Case Study of the California Tobacco Control Program and the California Smokers' Helpline.

PubMed

Lee, Youn Ok; Momin, Behnoosh; Hansen, Heather; Duke, Jennifer; Harms, Kristin; McCartney, Amanda; Neri, Antonio; Kahende, Jennifer; Zhang, Lei; Stewart, Sherri L

2014-01-01

Digital media are often used to encourage smoking cessation by increasing quitline call volume through direct promotion to smokers or indirect promotion to smoker proxies. The documentation of a program's experiences utilizing digital media is necessary to develop both the knowledge base and a set of best practices. This case study highlights the use of digital media in a proxy-targeted campaign to promote the California Smokers' Helpline to health care professionals from October 2009 to September 2012. We describe the iterative development of the campaign's digital media activities and report campaign summaries of web metrics (website visits, webinar registrations, downloads of online materials, online orders for promotional materials) and media buy (gross impressions) tracking data. The campaign generated more than 2.7 million gross impressions from digital media sources over 3 years. Online orders for promotional materials increased almost 40% over the course of the campaign. A clearly defined campaign strategy ensured that there was a systematic approach in developing and implementing campaign activities and ensuring that lessons learned from previous years were incorporated. Discussion includes lessons learned and recommendations for future improvements reported by campaign staff to inform similar efforts using digital media.

Maximizing the Impact of Digital Media Campaigns to Promote Smoking Cessation: A Case Study of the California Tobacco Control Program and the California Smokers’ Helpline

PubMed Central

Lee, Youn Ok; Momin, Behnoosh; Hansen, Heather; Duke, Jennifer; Harms, Kristin; McCartney, Amanda; Neri, Antonio; Kahende, Jennifer; Zhang, Lei; Stewart, Sherri L.

2017-01-01

Digital media are often used to encourage smoking cessation by increasing quitline call volume through direct promotion to smokers or indirect promotion to smoker proxies. The documentation of a program’s experiences utilizing digital media is necessary to develop both the knowledge base and a set of best practices. This case study highlights the use of digital media in a proxy-targeted campaign to promote the California Smokers’ Helpline to health care professionals from October 2009 to September 2012. We describe the iterative development of the campaign’s digital media activities and report campaign summaries of web metrics (website visits, webinar registrations, downloads of online materials, online orders for promotional materials) and media buy (gross impressions) tracking data. The campaign generated more than 2.7 million gross impressions from digital media sources over 3 years. Online orders for promotional materials increased almost 40% over the course of the campaign. A clearly defined campaign strategy ensured that there was a systematic approach in developing and implementing campaign activities and ensuring that lessons learned from previous years were incorporated. Discussion includes lessons learned and recommendations for future improvements reported by campaign staff to inform similar efforts using digital media. PMID:28239304

Numerical analysis of stiffened shells of revolution. Volume 4: Engineer's program manual for STARS-2S shell theory automated for rotational structures - 2 (statics) digital computer program

NASA Technical Reports Server (NTRS)

Svalbonas, V.; Ogilvie, P.

1973-01-01

The engineering programming information for the digital computer program for analyzing shell structures is presented. The program is designed to permit small changes such as altering the geometry or a table size to fit the specific requirements. Each major subroutine is discussed and the following subjects are included: (1) subroutine description, (2) pertinent engineering symbols and the FORTRAN coded counterparts, (3) subroutine flow chart, and (4) subroutine FORTRAN listing.

CMOS image sensor with organic photoconductive layer having narrow absorption band and proposal of stack type solid-state image sensors

NASA Astrophysics Data System (ADS)

Takada, Shunji; Ihama, Mikio; Inuiya, Masafumi

2006-02-01

Digital still cameras overtook film cameras in Japanese market in 2000 in terms of sales volume owing to their versatile functions. However, the image-capturing capabilities such as sensitivity and latitude of color films are still superior to those of digital image sensors. In this paper, we attribute the cause for the high performance of color films to their multi-layered structure, and propose the solid-state image sensors with stacked organic photoconductive layers having narrow absorption bands on CMOS read-out circuits.

A study of digital holographic filters generation. Phase 2: Digital data communication system, volume 1

NASA Technical Reports Server (NTRS)

Ingels, F. M.; Mo, C. D.

1978-01-01

An empirical study of the performance of the Viterbi decoders in bursty channels was carried out and an improved algebraic decoder for nonsystematic codes was developed. The hybrid algorithm was simulated for the (2,1), k = 7 code on a computer using 20 channels having various error statistics, ranging from pure random error to pure bursty channels. The hybrid system outperformed both the algebraic and the Viterbi decoders in every case, except the 1% random error channel where the Viterbi decoder had one bit less decoding error.

The analysis of delays in simulator digital computing systems. Volume 1: Formulation of an analysis approach using a central example simulator model

NASA Technical Reports Server (NTRS)

Heffley, R. K.; Jewell, W. F.; Whitbeck, R. F.; Schulman, T. M.

1980-01-01

The effects of spurious delays in real time digital computing systems are examined. Various sources of spurious delays are defined and analyzed using an extant simulator system as an example. A specific analysis procedure is set forth and four cases are viewed in terms of their time and frequency domain characteristics. Numerical solutions are obtained for three single rate one- and two-computer examples, and the analysis problem is formulated for a two-rate, two-computer example.

Removal of instrument signature from Mariner 9 television images of Mars

NASA Technical Reports Server (NTRS)

Green, W. B.; Jepsen, P. L.; Kreznar, J. E.; Ruiz, R. M.; Schwartz, A. A.; Seidman, J. B.

1975-01-01

The Mariner 9 spacecraft was inserted into orbit around Mars in November 1971. The two vidicon camera systems returned over 7300 digital images during orbital operations. The high volume of returned data and the scientific objectives of the Television Experiment made development of automated digital techniques for the removal of camera system-induced distortions from each returned image necessary. This paper describes the algorithms used to remove geometric and photometric distortions from the returned imagery. Enhancement processing of the final photographic products is also described.

Digital Cellular Solid Pressure Vessels: A Novel Approach for Human Habitation in Space

NASA Technical Reports Server (NTRS)

Cellucci, Daniel; Jenett, Benjamin; Cheung, Kenneth C.

2017-01-01

It is widely assumed that human exploration beyond Earth's orbit will require vehicles capable of providing long duration habitats that simulate an Earth-like environment - consistent artificial gravity, breathable atmosphere, and sufficient living space- while requiring the minimum possible launch mass. This paper examines how the qualities of digital cellular solids - high-performance, repairability, reconfigurability, tunable mechanical response - allow the accomplishment of long-duration habitat objectives at a fraction of the mass required for traditional structural technologies. To illustrate the impact digital cellular solids could make as a replacement to conventional habitat subsystems, we compare recent proposed deep space habitat structural systems with a digital cellular solids pressure vessel design that consists of a carbon fiber reinforced polymer (CFRP) digital cellular solid cylindrical framework that is lined with an ultra-high molecular weight polyethylene (UHMWPE) skin. We use the analytical treatment of a linear specific modulus scaling cellular solid to find the minimum mass pressure vessel for a structure and find that, for equivalent habitable volume and appropriate safety factors, the use of digital cellular solids provides clear methods for producing structures that are not only repairable and reconfigurable, but also higher performance than their conventionally manufactured counterparts.

Single-channel voice-response-system program documentation volume I : system description

DOT National Transportation Integrated Search

1977-01-01

This report documents the design and implementation of a Voice Response System (VRS) using Adaptive Differential Pulse Code Modulation (ADPCM) voice coding. Implemented on a Digital Equipment Corporation PDP-11/20,R this VRS system supports a single ...

North Atlantic (NAT) aided inertial navigation system simulation volume I. : technical results

DOT National Transportation Integrated Search

1973-07-01

Current air traffic operations over the North ATlantic (NAT) and the application of hybrid navigation systems to obtain more accurate performance on these NAT routes are reviewed. A digital computer simulation program (NATNAV - North ATlantic NAVigat...

Forest inventory using multistage sampling with probability proportional to size. [Brazil

NASA Technical Reports Server (NTRS)

Parada, N. D. J. (Principal Investigator); Lee, D. C. L.; Hernandezfilho, P.; Shimabukuro, Y. E.; Deassis, O. R.; Demedeiros, J. S.

1984-01-01

A multistage sampling technique, with probability proportional to size, for forest volume inventory using remote sensing data is developed and evaluated. The study area is located in the Southeastern Brazil. The LANDSAT 4 digital data of the study area are used in the first stage for automatic classification of reforested areas. Four classes of pine and eucalypt with different tree volumes are classified utilizing a maximum likelihood classification algorithm. Color infrared aerial photographs are utilized in the second stage of sampling. In the third state (ground level) the time volume of each class is determined. The total time volume of each class is expanded through a statistical procedure taking into account all the three stages of sampling. This procedure results in an accurate time volume estimate with a smaller number of aerial photographs and reduced time in field work.

Further development of the dynamic gas temperature measurement system. Volume 2: Computer program user's manual

NASA Technical Reports Server (NTRS)

Stocks, Dana R.

1986-01-01

The Dynamic Gas Temperature Measurement System compensation software accepts digitized data from two different diameter thermocouples and computes a compensated frequency response spectrum for one of the thermocouples. Detailed discussions of the physical system, analytical model, and computer software are presented in this volume and in Volume 1 of this report under Task 3. Computer program software restrictions and test cases are also presented. Compensated and uncompensated data may be presented in either the time or frequency domain. Time domain data are presented as instantaneous temperature vs time. Frequency domain data may be presented in several forms such as power spectral density vs frequency.

Morphometric analysis of Russian Plain's small lakes on the base of accurate digital bathymetric models

NASA Astrophysics Data System (ADS)

Naumenko, Mikhail; Guzivaty, Vadim; Sapelko, Tatiana

2016-04-01

Lake morphometry refers to physical factors (shape, size, structure, etc) that determine the lake depression. Morphology has a great influence on lake ecological characteristics especially on water thermal conditions and mixing depth. Depth analyses, including sediment measurement at various depths, volumes of strata and shoreline characteristics are often critical to the investigation of biological, chemical and physical properties of fresh waters as well as theoretical retention time. Management techniques such as loading capacity for effluents and selective removal of undesirable components of the biota are also dependent on detailed knowledge of the morphometry and flow characteristics. During the recent years a lake bathymetric surveys were carried out by using echo sounder with a high bottom depth resolution and GPS coordinate determination. Few digital bathymetric models have been created with 10*10 m spatial grid for some small lakes of Russian Plain which the areas not exceed 1-2 sq. km. The statistical characteristics of the depth and slopes distribution of these lakes calculated on an equidistant grid. It will provide the level-surface-volume variations of small lakes and reservoirs, calculated through combination of various satellite images. We discuss the methodological aspects of creating of morphometric models of depths and slopes of small lakes as well as the advantages of digital models over traditional methods.

Land Survey from Unmaned Aerial Veichle

NASA Astrophysics Data System (ADS)

Peterman, V.; Mesarič, M.

2012-07-01

In this paper we present, how we use a quadrocopter unmanned aerial vehicle with a camera attached to it, to do low altitude photogrammetric land survey. We use the quadrocopter to take highly overlapping photos of the area of interest. A "structure from motion" algorithm is implemented to get parameters of camera orientations and to generate a sparse point cloud representation of objects in photos. Than a patch based multi view stereo algorithm is applied to generate a dense point cloud. Ground control points are used to georeference the data. Further processing is applied to generate digital orthophoto maps, digital surface models, digital terrain models and assess volumes of various types of material. Practical examples of land survey from a UAV are presented in the paper. We explain how we used our system to monitor the reconstruction of commercial building, then how our UAV was used to assess the volume of coal supply for Ljubljana heating plant. Further example shows the usefulness of low altitude photogrammetry for documentation of archaeological excavations. In the final example we present how we used our UAV to prepare an underlay map for natural gas pipeline's route planning. In the final analysis we conclude that low altitude photogrammetry can help bridge the gap between laser scanning and classic tachymetric survey, since it offers advantages of both techniques.

Digitally programmable microfluidic automaton for multiscale combinatorial mixing and sample processing†

PubMed Central

Jensen, Erik C.; Stockton, Amanda M.; Chiesl, Thomas N.; Kim, Jungkyu; Bera, Abhisek; Mathies, Richard A.

2013-01-01

A digitally programmable microfluidic Automaton consisting of a 2-dimensional array of pneumatically actuated microvalves is programmed to perform new multiscale mixing and sample processing operations. Large (µL-scale) volume processing operations are enabled by precise metering of multiple reagents within individual nL-scale valves followed by serial repetitive transfer to programmed locations in the array. A novel process exploiting new combining valve concepts is developed for continuous rapid and complete mixing of reagents in less than 800 ms. Mixing, transfer, storage, and rinsing operations are implemented combinatorially to achieve complex assay automation protocols. The practical utility of this technology is demonstrated by performing automated serial dilution for quantitative analysis as well as the first demonstration of on-chip fluorescent derivatization of biomarker targets (carboxylic acids) for microchip capillary electrophoresis on the Mars Organic Analyzer. A language is developed to describe how unit operations are combined to form a microfluidic program. Finally, this technology is used to develop a novel microfluidic 6-sample processor for combinatorial mixing of large sets (>26 unique combinations) of reagents. The digitally programmable microfluidic Automaton is a versatile programmable sample processor for a wide range of process volumes, for multiple samples, and for different types of analyses. PMID:23172232

3-D Digitization of Stereoscopic Jet-in-Crossflow Vortex Structure Images via Augmented Reality

NASA Astrophysics Data System (ADS)

Sigurdson, Lorenz; Strand, Christopher; Watson, Graeme; Nault, Joshua; Tucker, Ryan

2006-11-01

Stereoscopic images of smoke-laden vortex flows have proven useful for understanding the topology of the embedded 3-D vortex structures. Images from two cameras allow a perception of the 3-D structure via the use of red/blue eye glasses. The human brain has an astonishing capacity to calculate and present to the observer the complex turbulent smoke volume. We have developed a technique whereby a virtual cursor is introduced to the perception, which creates an ``augmented reality.'' The perceived position of this cursor in the 3-D field can be precisely controlled by the observer. It can be brought near a characteristic vortex structure in order to digitally estimate the spatial coordinates of that feature. A calibration procedure accounts for camera positioning. Vortex tubes can be traced and recorded for later or real time supersposition of tube skeleton models. These models can be readily digitally obtained for display in graphics systems to allow complete exploration from any location or perspective. A unique feature of this technology is the use of the human brain to naturally perform the difficult computation of the shape of the translucent smoke volume. Examples are given of application to low velocity ratio and Reynolds number elevated jets-in-crossflow.

Digital recovery, modification, and analysis of Tetra Tech seismic horizon mapping, National Petroleum Reserve Alaska (NPRA), northern Alaska

USGS Publications Warehouse

Saltus, R.W.; Kulander, Christopher S.; Potter, Christopher J.

2002-01-01

We have digitized, modified, and analyzed seismic interpretation maps of 12 subsurface stratigraphic horizons spanning portions of the National Petroleum Reserve in Alaska (NPRA). These original maps were prepared by Tetra Tech, Inc., based on about 15,000 miles of seismic data collected from 1974 to 1981. We have also digitized interpreted faults and seismic velocities from Tetra Tech maps. The seismic surfaces were digitized as two-way travel time horizons and converted to depth using Tetra Tech seismic velocities. The depth surfaces were then modified by long-wavelength corrections based on recent USGS seismic re-interpretation along regional seismic lines. We have developed and executed an algorithm to identify and calculate statistics on the area, volume, height, and depth of closed structures based on these seismic horizons. These closure statistics are tabulated and have been used as input to oil and gas assessment calculations for the region. Directories accompanying this report contain basic digitized data, processed data, maps, tabulations of closure statistics, and software relating to this project.

1994 ASPRS/ACSM annual convention exposition. Volume 2

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1994-01-01

This report is Volume II of presented papers at the joint 1994 convention of the American Society for Photgrammetry and Remote Sensing and American Congress on Surveying and Mapping. Topic areas covered include the following: Data Base/GPS Issues; Survey Management Issues; Surveying computations; Surveying education; Digital mapping; global change, EOS and NALC issues; GPS issues; Battelle Research in Remote Sensing and in GIS; Advanced Image Processing;GIS Issues; Surveying and Geodesy Issues; water resource issues; Advanced applications of remote sensing; Landsat Pathfinder I.

A slice of π: An exploratory neuroimaging study of digit encoding and retrieval in a superior memorist

PubMed Central

Raz, Amir; Packard, Mark G.; Alexander, Gerianne M.; Buhle, Jason T.; Zhu, Hongtu; Yu, Shan; Peterson, Bradley S.

2015-01-01

Subject PI demonstrated superior memory using a variant of a Method of Loci (MOL) technique to recite the first digits of the mathematical constant π to more than 216 decimal places. We report preliminary behavioral, functional magnetic resonance imaging (fMRI), and brain volumetric data from PI. fMRI data collected while PI recited the first 540 digits of π (i.e., during retrieval) revealed increased activity in medial frontal gyrus and dorsolateral prefrontal cortex. Encoding of a novel string of 100 random digits activated motor association areas, midline frontal regions, and visual association areas. Volumetric analyses indicated an increased volume of the right subgenual cingulate, a brain region implicated in emotion, mentalizing, and autonomic arousal. Wechsler Abbreviated Scale of Intelligence (WASI) testing indicated that PI is of average intelligence, and performance on mirror tracing, rotor pursuit, and the Silverman and Eals Location Memory Task revealed normal procedural and implicit memory. PI’s performance on the Wechsler Memory Scale (WMS-III) revealed average general memory abilities (50th percentile), but superior working memory abilities (99th percentile). Surprisingly, PI’s visual memory (WMS-III) for neutral faces and common events was remarkably poor (3rd percentile). PI’s self-report indicates that imagining affective situations and high emotional content is critical for successful recall. We speculate that PI’s reduced memory for neutral/non-emotional faces and common events, and the observed increase in volume of the right subgenual cingulate, may be related to extensive practice with memorizing highly emotional material. PMID:19585350

A slice of pi : an exploratory neuroimaging study of digit encoding and retrieval in a superior memorist.

PubMed

Raz, Amir; Packard, Mark G; Alexander, Gerianne M; Buhle, Jason T; Zhu, Hongtu; Yu, Shan; Peterson, Bradley S

2009-10-01

Subject PI demonstrated superior memory using a variant of a Method of Loci (MOL) technique to recite the first digits of the mathematical constant pi to more than 2(16) decimal places. We report preliminary behavioral, functional magnetic resonance imaging (fMRI), and brain volumetric data from PI. fMRI data collected while PI recited the first 540 digits of pi (i.e., during retrieval) revealed increased activity in medial frontal gyrus and dorsolateral prefrontal cortex. Encoding of a novel string of 100 random digits activated motor association areas, midline frontal regions, and visual association areas. Volumetric analyses indicated an increased volume of the right subgenual cingulate, a brain region implicated in emotion, mentalizing, and autonomic arousal. Wechsler Abbreviated Scale of Intelligence (WASI) testing indicated that PI is of average intelligence, and performance on mirror tracing, rotor pursuit, and the Silverman and Eals Location Memory Task revealed normal procedural and implicit memory. PI's performance on the Wechsler Memory Scale (WMS-III) revealed average general memory abilities (50th percentile), but superior working memory abilities (99th percentile). Surprisingly, PI's visual memory (WMS-III) for neutral faces and common events was remarkably poor (3rd percentile). PI's self-report indicates that imagining affective situations and high emotional content is critical for successful recall. We speculate that PI's reduced memory for neutral/non-emotional faces and common events, and the observed increase in volume of the right subgenual cingulate, may be related to extensive practice with memorizing highly emotional material.

Applications in Data-Intensive Computing

DOE Office of Scientific and Technical Information (OSTI.GOV)

Shah, Anuj R.; Adkins, Joshua N.; Baxter, Douglas J.

2010-04-01

This book chapter, to be published in Advances in Computers, Volume 78, in 2010 describes applications of data intensive computing (DIC). This is an invited chapter resulting from a previous publication on DIC. This work summarizes efforts coming out of the PNNL's Data Intensive Computing Initiative. Advances in technology have empowered individuals with the ability to generate digital content with mouse clicks and voice commands. Digital pictures, emails, text messages, home videos, audio, and webpages are common examples of digital content that are generated on a regular basis. Data intensive computing facilitates human understanding of complex problems. Data-intensive applications providemore » timely and meaningful analytical results in response to exponentially growing data complexity and associated analysis requirements through the development of new classes of software, algorithms, and hardware.« less

Application of Remote Sensing Data to Improve the Water and Soil Resource Management of Rwanda

NASA Astrophysics Data System (ADS)

Csorba, Ádám; Bukombe, Benjamin; Naramabuye, Francois Xavier; Szegi, Tamás; Vekerdy, Zoltán; Michéli, Erika

2017-04-01

The Rwandan agriculture strongly relies in the dry seasons on the water stored in artificial reservoirs of various sizes for irrigation purposes. Furthermore, the success of irrigation depends on a wide range of soil properties which directly affect the moisture regime of the growing medium. By integrating remote sensing and auxiliary data the objectives of our study are to monitor the water level fluctuation in the reservoirs, estimate the volume of water available for irrigation and to combine this information with soil property maps to support the decision making for sustainable irrigation water management in a study area in Southern Rwanda. For water level and volume estimation a series of Sentinel-1 (product type: GRD, acquisition mode: IW, polarizations HH and VH) data were obtained covering the study area and spanning over a period of two years. To map the extent of water bodies the Radar-Based Water Body Mapping module of the Water Observation and Information System (WOIS) was used. High-resolution optical data (Sentinel-2) were used for validation in cloud-free periods. To estimate the volume changes in the reservoirs, we combined the information derived from the water body mapping procedure and digital elevation models. For sustainable irrigation water management, digital soil property maps were developed by the application of wide range of environmental covariates related to soil forming factors. To develop covariates which represent the land use a time series analysis of the 2 years of Sentinel-1 data was performed. As auxiliary soil data, the ISRIC-WISE harmonized soil profile database was used. The developed digital soil mapping approach is integrated into a new WOIS workflow.

Performance of dense digital surface models based on image matching in the estimation of plot-level forest variables

NASA Astrophysics Data System (ADS)

Nurminen, Kimmo; Karjalainen, Mika; Yu, Xiaowei; Hyyppä, Juha; Honkavaara, Eija

2013-09-01

Recent research results have shown that the performance of digital surface model extraction using novel high-quality photogrammetric images and image matching is a highly competitive alternative to laser scanning. In this article, we proceed to compare the performance of these two methods in the estimation of plot-level forest variables. Dense point clouds extracted from aerial frame images were used to estimate the plot-level forest variables needed in a forest inventory covering 89 plots. We analyzed images with 60% and 80% forward overlaps and used test plots with off-nadir angles of between 0° and 20°. When compared to reference ground measurements, the airborne laser scanning (ALS) data proved to be the most accurate: it yielded root mean square error (RMSE) values of 6.55% for mean height, 11.42% for mean diameter, and 20.72% for volume. When we applied a forward overlap of 80%, the corresponding results from aerial images were 6.77% for mean height, 12.00% for mean diameter, and 22.62% for volume. A forward overlap of 60% resulted in slightly deteriorated RMSE values of 7.55% for mean height, 12.20% for mean diameter, and 22.77% for volume. According to our results, the use of higher forward overlap produced only slightly better results in the estimation of these forest variables. Additionally, we found that the estimation accuracy was not significantly impacted by the increase in the off-nadir angle. Our results confirmed that digital aerial photographs were about as accurate as ALS in forest resources estimation as long as a terrain model was available.

Estimation of regional material yield from coastal landslides based on historical digital terrain modelling

USGS Publications Warehouse

Hapke, C.J.

2005-01-01

High-resolution historical (1942) and recent (1994) digital terrain models were derived from aerial photographs along the Big Sur coastline in central California to measure the long-term volume of material that enters the nearshore environment. During the 52-year measurement time period, an average of 21 000 ?? 3100 m3 km-1 a-1 of material was eroded from nine study sections distributed along the coast, with a low yield of 1000 ?? 240 m3 km-1 a-1 and a high of 46 700 ?? 7300 m3 km-1 a-1. The results compare well with known volumes from several deep-seated landslides in the area and suggest that the processes by which material is delivered to the coast are episodic in nature. In addition, a number of parameters are investigated to determine what influences the substantial variation in yield along the coast. It is found that the magnitude of regional coastal landslide sediment yield is primarily related to the physical strength of the slope-forming material. Coastal Highway 1 runs along the lower portion of the slope along this stretch of coastline, and winter storms frequently damage the highway. The California Department of Transportation is responsible for maintaining this scenic highway while minimizing the impacts to the coastal ecosystems that are part of the Monterey Bay National Marine Sanctuary. This study provides environmental managers with critical background data on the volumes of material that historically enter the nearshore from landslides, as well as demonstrating the application of deriving historical digital terrain data to model landscape evolution. Published in 2005 by John Wiley & Sons, Ltd.

Multi-level computational methods for interdisciplinary research in the HathiTrust Digital Library

PubMed Central

Allen, Colin; Börner, Katy; Light, Robert; McAlister, Simon; Ravenscroft, Andrew; Rose, Robert; Rose, Doori; Otsuka, Jun; Bourget, David; Lawrence, John; Reed, Chris

2017-01-01

We show how faceted search using a combination of traditional classification systems and mixed-membership topic models can go beyond keyword search to inform resource discovery, hypothesis formulation, and argument extraction for interdisciplinary research. Our test domain is the history and philosophy of scientific work on animal mind and cognition. The methods can be generalized to other research areas and ultimately support a system for semi-automatic identification of argument structures. We provide a case study for the application of the methods to the problem of identifying and extracting arguments about anthropomorphism during a critical period in the development of comparative psychology. We show how a combination of classification systems and mixed-membership models trained over large digital libraries can inform resource discovery in this domain. Through a novel approach of “drill-down” topic modeling—simultaneously reducing both the size of the corpus and the unit of analysis—we are able to reduce a large collection of fulltext volumes to a much smaller set of pages within six focal volumes containing arguments of interest to historians and philosophers of comparative psychology. The volumes identified in this way did not appear among the first ten results of the keyword search in the HathiTrust digital library and the pages bear the kind of “close reading” needed to generate original interpretations that is the heart of scholarly work in the humanities. Zooming back out, we provide a way to place the books onto a map of science originally constructed from very different data and for different purposes. The multilevel approach advances understanding of the intellectual and societal contexts in which writings are interpreted. PMID:28922416

Multi-level computational methods for interdisciplinary research in the HathiTrust Digital Library.

PubMed

Murdock, Jaimie; Allen, Colin; Börner, Katy; Light, Robert; McAlister, Simon; Ravenscroft, Andrew; Rose, Robert; Rose, Doori; Otsuka, Jun; Bourget, David; Lawrence, John; Reed, Chris

2017-01-01

We show how faceted search using a combination of traditional classification systems and mixed-membership topic models can go beyond keyword search to inform resource discovery, hypothesis formulation, and argument extraction for interdisciplinary research. Our test domain is the history and philosophy of scientific work on animal mind and cognition. The methods can be generalized to other research areas and ultimately support a system for semi-automatic identification of argument structures. We provide a case study for the application of the methods to the problem of identifying and extracting arguments about anthropomorphism during a critical period in the development of comparative psychology. We show how a combination of classification systems and mixed-membership models trained over large digital libraries can inform resource discovery in this domain. Through a novel approach of "drill-down" topic modeling-simultaneously reducing both the size of the corpus and the unit of analysis-we are able to reduce a large collection of fulltext volumes to a much smaller set of pages within six focal volumes containing arguments of interest to historians and philosophers of comparative psychology. The volumes identified in this way did not appear among the first ten results of the keyword search in the HathiTrust digital library and the pages bear the kind of "close reading" needed to generate original interpretations that is the heart of scholarly work in the humanities. Zooming back out, we provide a way to place the books onto a map of science originally constructed from very different data and for different purposes. The multilevel approach advances understanding of the intellectual and societal contexts in which writings are interpreted.

Multistage variable probability forest volume inventory. [Defiance Unit of the Navajo Nation in Arizona and Colorado

NASA Technical Reports Server (NTRS)

Anderson, J. E. (Principal Investigator)

1979-01-01

The net board foot volume (Scribner log rule) of the standing Ponderosa pine timber on the Defiance Unit of the Navajo Nation's forested land was estimated using a multistage forest volume inventory scheme with variable sample selection probabilities. The inventory designed to accomplish this task required that both LANDSAT MSS digital data and aircraft acquired data be used to locate one acre ground splits, which were subsequently visited by ground teams conducting detailed tree measurements using an optical dendrometer. The dendrometer measurements were then punched on computer input cards and were entered in a computer program developed by the U.S. Forest Service. The resulting individual tree volume estimates were then expanded through the use of a statistically defined equation to produce the volume estimate for the entire area which includes 192,026 acres and is approximately a 44% the total forested area of the Navajo Nation.

Benefit-Cost Analysis of Integrated Paratransit Systems : Volume 5. The Impacts of Technological Innovation.

DOT National Transportation Integrated Search

1979-09-01

A number of new technologies have been implemented with or proposed for paratransit systems. As part of the overall IP benefit cost study, the potential impact of two such technologies, digital communications and computer dispatching, have been analy...

Trends in Transforming Scholarly Communication and Their Implications.

ERIC Educational Resources Information Center

Liu, Ziming

2003-01-01

Explores trends in transforming scholarly publishing and possible implications for electronic publishing and digital libraries. Topics include changes in collaborative research; changes in volume of information production; and age of cited documents and how older documents are used in today's network environment. (Author/LRW)

Application of Laser Scanning Confocal Microscopy to Heat and Mass Transport Modeling in Porous Microstructures

NASA Technical Reports Server (NTRS)

Marshall, Jochen; Milos, Frank; Fredrich, Joanne; Rasky, Daniel J. (Technical Monitor)

1997-01-01

Laser Scanning Confocal Microscopy (LSCM) has been used to obtain digital images of the complicated 3-D (three-dimensional) microstructures of rigid, fibrous thermal protection system (TPS) materials. These orthotropic materials are comprised of refractory ceramic fibers with diameters in the range of 1 to 10 microns and have open porosities of 0.8 or more. Algorithms are being constructed to extract quantitative microstructural information from the digital data so that it may be applied to specific heat and mass transport modeling efforts; such information includes, for example, the solid and pore volume fractions, the internal surface area per volume, fiber diameter distributions, and fiber orientation distributions. This type of information is difficult to obtain in general, yet it is directly relevant to many computational efforts which seek to model macroscopic thermophysical phenomena in terms of microscopic mechanisms or interactions. Two such computational efforts for fibrous TPS materials are: i) the calculation of radiative transport properties; ii) the modeling of gas permeabilities.

Reconstruction and Simulation of Neocortical Microcircuitry.

PubMed

Markram, Henry; Muller, Eilif; Ramaswamy, Srikanth; Reimann, Michael W; Abdellah, Marwan; Sanchez, Carlos Aguado; Ailamaki, Anastasia; Alonso-Nanclares, Lidia; Antille, Nicolas; Arsever, Selim; Kahou, Guy Antoine Atenekeng; Berger, Thomas K; Bilgili, Ahmet; Buncic, Nenad; Chalimourda, Athanassia; Chindemi, Giuseppe; Courcol, Jean-Denis; Delalondre, Fabien; Delattre, Vincent; Druckmann, Shaul; Dumusc, Raphael; Dynes, James; Eilemann, Stefan; Gal, Eyal; Gevaert, Michael Emiel; Ghobril, Jean-Pierre; Gidon, Albert; Graham, Joe W; Gupta, Anirudh; Haenel, Valentin; Hay, Etay; Heinis, Thomas; Hernando, Juan B; Hines, Michael; Kanari, Lida; Keller, Daniel; Kenyon, John; Khazen, Georges; Kim, Yihwa; King, James G; Kisvarday, Zoltan; Kumbhar, Pramod; Lasserre, Sébastien; Le Bé, Jean-Vincent; Magalhães, Bruno R C; Merchán-Pérez, Angel; Meystre, Julie; Morrice, Benjamin Roy; Muller, Jeffrey; Muñoz-Céspedes, Alberto; Muralidhar, Shruti; Muthurasa, Keerthan; Nachbaur, Daniel; Newton, Taylor H; Nolte, Max; Ovcharenko, Aleksandr; Palacios, Juan; Pastor, Luis; Perin, Rodrigo; Ranjan, Rajnish; Riachi, Imad; Rodríguez, José-Rodrigo; Riquelme, Juan Luis; Rössert, Christian; Sfyrakis, Konstantinos; Shi, Ying; Shillcock, Julian C; Silberberg, Gilad; Silva, Ricardo; Tauheed, Farhan; Telefont, Martin; Toledo-Rodriguez, Maria; Tränkler, Thomas; Van Geit, Werner; Díaz, Jafet Villafranca; Walker, Richard; Wang, Yun; Zaninetta, Stefano M; DeFelipe, Javier; Hill, Sean L; Segev, Idan; Schürmann, Felix

2015-10-08

We present a first-draft digital reconstruction of the microcircuitry of somatosensory cortex of juvenile rat. The reconstruction uses cellular and synaptic organizing principles to algorithmically reconstruct detailed anatomy and physiology from sparse experimental data. An objective anatomical method defines a neocortical volume of 0.29 ± 0.01 mm(3) containing ~31,000 neurons, and patch-clamp studies identify 55 layer-specific morphological and 207 morpho-electrical neuron subtypes. When digitally reconstructed neurons are positioned in the volume and synapse formation is restricted to biological bouton densities and numbers of synapses per connection, their overlapping arbors form ~8 million connections with ~37 million synapses. Simulations reproduce an array of in vitro and in vivo experiments without parameter tuning. Additionally, we find a spectrum of network states with a sharp transition from synchronous to asynchronous activity, modulated by physiological mechanisms. The spectrum of network states, dynamically reconfigured around this transition, supports diverse information processing strategies. VIDEO ABSTRACT. Copyright © 2015 Elsevier Inc. All rights reserved.

Direct Comparison of a Tablet Computer and a Personal Digital Assistant for Point-of-Care Documentation in Eye Care

PubMed Central

Silvey, Garry M.; Macri, Jennifer M.; Lee, Paul P.; Lobach, David F.

2005-01-01

New mobile computing devices including personal digital assistants (PDAs) and tablet computers have emerged to facilitate data collection at the point of care. Unfortunately, little research has been reported regarding which device is optimal for a given care setting. In this study we created and compared functionally identical applications on a Palm operating system-based PDA and a Windows-based tablet computer for point-of-care documentation of clinical observations by eye care professionals when caring for patients with diabetes. Eye-care professionals compared the devices through focus group sessions and through validated usability surveys. We found that the application on the tablet computer was preferred over the PDA for documenting the complex data related to eye care. Our findings suggest that the selection of a mobile computing platform depends on the amount and complexity of the data to be entered; the tablet computer functions better for high volume, complex data entry, and the PDA, for low volume, simple data entry. PMID:16779128

Ultrasensitive Detection of Shigella Species in Blood and Stool.

PubMed

Luo, Jieling; Wang, Jiapeng; Mathew, Anup S; Yau, Siu-Tung

2016-02-16

A modified immunosensing system with voltage-controlled signal amplification was used to detect Shigella in stool and blood matrixes at the single-digit CFU level. Inactivated Shigella was spiked in these matrixes and detected directly. The detection was completed in 78 min. Detection limits of 21 CFU/mL and 18 CFU/mL were achieved in stool and blood, respectively, corresponding to 2-7 CFUs immobilized on the detecting electrode. The outcome of the detection of extremely low bacterium concentration, i.e., below 100 CFU/mL, blood samples show a random nature. An analysis of the detection probabilities indicates the correlation between the sample volume and the success of detection and suggests that sample volume is critical for ultrasensitive detection of bacteria. The calculated detection limit is qualitatively in agreement with the empirically determined detection limit. The demonstrated ultrasensitive detection of Shigella on the single-digit CFU level suggests the feasibility of the direct detection of the bacterium in the samples without performing a culture.

Forecast Modelling via Variations in Binary Image-Encoded Information Exploited by Deep Learning Neural Networks.

PubMed

Liu, Da; Xu, Ming; Niu, Dongxiao; Wang, Shoukai; Liang, Sai

2016-01-01

Traditional forecasting models fit a function approximation from dependent invariables to independent variables. However, they usually get into trouble when date are presented in various formats, such as text, voice and image. This study proposes a novel image-encoded forecasting method that input and output binary digital two-dimensional (2D) images are transformed from decimal data. Omitting any data analysis or cleansing steps for simplicity, all raw variables were selected and converted to binary digital images as the input of a deep learning model, convolutional neural network (CNN). Using shared weights, pooling and multiple-layer back-propagation techniques, the CNN was adopted to locate the nexus among variations in local binary digital images. Due to the computing capability that was originally developed for binary digital bitmap manipulation, this model has significant potential for forecasting with vast volume of data. The model was validated by a power loads predicting dataset from the Global Energy Forecasting Competition 2012.

A proposed magnetic digital temperature transducer, volume 1

NASA Technical Reports Server (NTRS)

Collier, T. E.; Tchernev, D. I.; Hartwig, W. H.

1972-01-01

A study has been made of the feasibility of using the discontinuous permeability versus temperature characteristics of some magnetic materials for a digital temperature transducer and a thermally controlled ON-OFF switch. Simple logic converts the number of output pulse to a digital word recognizable by the system. Efforts have been concentrated on materials with Curie temperatures between 0 and 100 C. One compound has the composition Mn(5-x)Fe(x)Ge3 where the amount of iron determines the transition temperature. The other compound is Ni-Zn ferrite and has the compositon Ni(1-x)Zn(x)Fe(1.95)O4 where the nickel: zinc ratio determines the transition temperature. A detailed report of materials prepared is presented. Toroidal inductors of the material have been constructed and the change in inductance with temperature measured. In view of these initial measurements, it is felt that a transducer utilizing the permeability versus temperature characteristics of these materials has promise as a reliable and sensitive solid state digital temperature transducer.

Forecast Modelling via Variations in Binary Image-Encoded Information Exploited by Deep Learning Neural Networks

PubMed Central

Xu, Ming; Niu, Dongxiao; Wang, Shoukai; Liang, Sai

2016-01-01

Traditional forecasting models fit a function approximation from dependent invariables to independent variables. However, they usually get into trouble when date are presented in various formats, such as text, voice and image. This study proposes a novel image-encoded forecasting method that input and output binary digital two-dimensional (2D) images are transformed from decimal data. Omitting any data analysis or cleansing steps for simplicity, all raw variables were selected and converted to binary digital images as the input of a deep learning model, convolutional neural network (CNN). Using shared weights, pooling and multiple-layer back-propagation techniques, the CNN was adopted to locate the nexus among variations in local binary digital images. Due to the computing capability that was originally developed for binary digital bitmap manipulation, this model has significant potential for forecasting with vast volume of data. The model was validated by a power loads predicting dataset from the Global Energy Forecasting Competition 2012. PMID:27281032

The challenges and opportunities in medical education for digital 'natives' and 'immigrants' in Scotland and abroad.

PubMed

de Wet, Carl; Yelland, Michael

2015-11-01

Although the digital revolution only started towards the end of the twentieth century, it has already dramatically shifted our world away from traditional industries and ushered in a new age of information. Virtually every aspect of our modern lives has either been transformed or challenged, including medical education. This article describes three of the important factors that are causing seismic changes in medical education in Scotland and abroad. The first is the new generation of 'digital natives' that are arriving in medical schools. In response, faculty members have had to become 'digital immigrants' and adapt their pedagogies. Second, the rise of social media has allowed the creation of virtual learning environments and communities that augment but also compete with traditional brick-and-mortar institutions. Finally, an ever-increasing range of e-learning resources promise freely accessible and up-to-date evidence, but their sheer volume and lack of standardisation will require careful curation. © The Author(s) 2015.

Automated complete slide digitization: a medium for simultaneous viewing by multiple pathologists.

PubMed

Leong, F J; McGee, J O

2001-11-01

Developments in telepathology robotic systems have evolved the concept of a 'virtual microscope' handling 'digital slides'. Slide digitization is a method of archiving salient histological features in numerical (digital) form. The value and potential of this have begun to be recognized by several international centres. Automated complete slide digitization has application at all levels of clinical practice and will benefit undergraduate, postgraduate, and continuing education. Unfortunately, as the volume of potential data on a histological slide represents a significant problem in terms of digitization, storage, and subsequent manipulation, the reality of virtual microscopy to date has comprised limited views at inadequate resolution. This paper outlines a system refined in the authors' laboratory, which employs a combination of enhanced hardware, image capture, and processing techniques designed for telepathology. The system is able to scan an entire slide at high magnification and create a library of such slides that may exist on an internet server or be distributed on removable media (such as CD-ROM or DVD). A digital slide allows image data manipulation at a level not possible with conventional light microscopy. Combinations of multiple users, multiple magnifications, annotations, and addition of ancillary textual and visual data are now possible. This demonstrates that with increased sophistication, the applications of telepathology technology need not be confined to second opinion, but can be extended on a wider front. Copyright 2001 John Wiley & Sons, Ltd.

All-Digital Baseband 65nm PLL/FPLL Clock Multiplier using 10-cell Library

NASA Technical Reports Server (NTRS)

Shuler, Robert L., Jr.; Wu, Qiong; Liu, Rui; Chen, Li

2014-01-01

PLLs for clock generation are essential for modern circuits, to generate specialized frequencies for many interfaces and high frequencies for chip internal operation. These circuits depend on analog circuits and careful tailoring for each new process, and making them fault tolerant is an incompletely solved problem. Until now, all digital PLLs have been restricted to sampled data DSP techniques and not available for the highest frequency baseband applications. This paper presents the design and preliminary evaluation of an all-digital baseband technique built entirely with an easily portable 10-cell digital library. The library is also described, as it aids in research and low volume design porting to new processes. The advantages of the digital approach are the wide variety of techniques available to give varying degrees of fault tolerance, and the simplicity of porting the design to new processes, even to exotic processes that may not have analog capability. The only tuning parameter is digital gate delay. An all-digital approach presents unique problems and standard analog loop stability design criteria cannot be directly used. Because of the quantization of frequency, there is effectively infinite gain for very small loop error feedback. The numerically controlled oscillator (NCO) based on a tapped delay line cannot be reliably updated while a pulse is active in the delay line, and ordinarily does not have enough frequency resolution for a low-jitter output.

ALL-Digital Baseband 65nm PLL/FPLL Clock Multiplier Using 10-Cell Library

NASA Technical Reports Server (NTRS)

Schuler, Robert L., Jr.; Wu, Qiong; Liu, Rui; Chen, Li; Madala, Shridhar

2014-01-01

PLLs for clock generation are essential for modern circuits, to generate specialized frequencies for many interfaces and high frequencies for chip internal operation. These circuits depend on analog circuits and careful tailoring for each new process, and making them fault tolerant is an incompletely solved problem. Until now, all digital PLLs have been restricted to sampled data DSP techniques and not available for the highest frequency baseband applications. This paper presents the design and preliminary evaluation of an all-digital baseband technique built entirely with an easily portable 10-cell digital library. The library is also described, as it aids in research and low volume design porting to new processes. The advantages of the digital approach are the wide variety of techniques available to give varying degrees of fault tolerance, and the simplicity of porting the design to new processes, even to exotic processes that may not have analog capability. The only tuning parameter is digital gate delay. An all-digital approach presents unique problems and standard analog loop stability design criteria cannot be directly used. Because of the quantization of frequency, there is effectively infinite gain for very small loop error feedback. The numerically controlled oscillator (NCO) based on a tapped delay line cannot be reliably updated while a pulse is active in the delay line, and ordinarily does not have enough frequency resolution for a low-jitter output.

Effect of orbital bony decompression for Graves' orbitopathy on the volume of extraocular muscles.

PubMed

Alsuhaibani, Adel H; Carter, Keith D; Policeni, Bruno; Nerad, Jeffrey A

2011-09-01

To evaluate the change in the rectus muscle volume following orbital bony wall decompression for Graves' orbitopathy. We used a computer program (syngo Volume Evaluation) to measure the rectus muscles from the digital preoperative and postoperative orbital CT. Of the 25 patients (20 women and five men; mean age 46 (range 18-64) years) enrolled in the study. A significant increase (mean 0.23 ml (16.5%) of preoperative volume; p=0.005) in the volume of the medial rectus muscle (MRM) was detected postoperatively, whereas no significant changes were found in the volume of the other rectus muscles and between eyes that underwent surgery in the active and inactive phases of the disease. A significant negative association was observed between the time of postoperative CT scans and the change in the MRM volume (p=0.0004) (a mean increase of 68% of preoperative MRM volume for those measured between 3 and 9 months, and a mean decrease in the volume of 50% for those measured between 41 and 50 months). The change in the volume of the MRM may partly explain the variability in the proptosis reduction following orbital decompression.

Marginal Fit of Lithium Disilicate Crowns Fabricated Using Conventional and Digital Methodology: A Three-Dimensional Analysis.

PubMed

Mostafa, Nezrine Z; Ruse, N Dorin; Ford, Nancy L; Carvalho, Ricardo M; Wyatt, Chris C L

2018-02-01

To compare the marginal fit of lithium disilicate (LD) crowns fabricated with digital impression and manufacturing (DD), digital impression and traditional pressed manufacturing (DP), and traditional impression and manufacturing (TP). Tooth #15 was prepared for all-ceramic crowns on an ivorine typodont. There were 45 LD crowns fabricated using three techniques: DD, DP, and TP. Microcomputed tomography (micro-CT) was used to assess the 2D and 3D marginal fit of crowns in all three groups. The 2D vertical marginal gap (MG) measurements were done at 20 systematically selected points/crown, while the 3D measurements represented the 3D volume of the gap measured circumferentially at the crown margin. Frequencies of different marginal discrepancies were also recorded, including overextension (OE), underextension (UE), and marginal chipping. Crowns with vertical MG > 120 μm at more than five points were considered unacceptable and were rejected. The results were analyzed by one-way ANOVA with Scheffe post hoc test (α = 0.05). DD crowns demonstrated significantly smaller mean vertical MG (33.3 ± 19.99 μm) compared to DP (54.08 ± 32.34 μm) and TP (51.88 ± 35.34 μm) crowns. Similarly, MG volume was significantly lower in the DD group (3.32 ± 0.58 mm 3 ) compared to TP group (4.16 ± 0.59 mm 3 ). The mean MG volume for the DP group (3.55 ± 0.78 mm 3 ) was not significantly different from the other groups. The occurrence of underextension error was higher in DP (6.25%) and TP (5.4%) than in DD (0.33%) group, while overextension was more frequent in DD (37.67%) than in TP (28.85%) and DP (18.75%) groups. Overall, 4 out of 45 crowns fabricated were deemed unacceptable based on the vertical MG measurements (three in TP group and one in DP group; all crowns in DD group were deemed acceptable). The results suggested that digital impression and CAD/CAM technology is a suitable, better alternative to traditional impression and manufacturing. © 2017 by the American College of Prosthodontists.

Searching the Internet for psychiatric disorders among Arab and Jewish Israelis: insights from a comprehensive infodemiological survey.

PubMed

Adawi, Mohammad; Amital, Howard; Mahamid, Mahmud; Amital, Daniela; Bisharat, Bishara; Mahroum, Naim; Sharif, Kassem; Guy, Adi; Adawi, Amin; Mahagna, Hussein; Abu Much, Arsalan; Watad, Samaa; Bragazzi, Nicola Luigi; Watad, Abdulla

2018-01-01

Israel represents a complex and pluralistic society comprising two major ethno-national groups, Israeli Jews and Israeli Arabs, which differ in terms of religious and cultural values as well as social constructs. According to the so-called "diversification hypothesis", within the framework of e-health and in the era of new information and communication technologies, seeking online health information could be a channel to increase health literacy, especially among disadvantaged groups. However, little is known concerning digital seeking behavior and, in particular, digital mental health literacy. This study was conducted in order to fill in this gap. Concerning raw figures, unadjusted for confounding variables (time, population size, Internet penetration index, disease rate), "depression" searched in Hebrew was characterized by 1.5 times higher search volumes, slightly declining throughout time, whereas relative search volumes (RSVs) related to "depression" searched in Arabic tended to increase over the years. Similar patterns could be detected for "phobia" (in Hebrew 1.4-fold higher than in Arabic) and for "anxiety" (with the searches performed in Hebrew 2.3 times higher than in Arabic). "Suicide" in Hebrew was searched 2.0-fold more than in Arabic (interestingly for both languages search volumes exhibited seasonal cyclic patterns). Eating disorders were searched more in Hebrew: 8.0-times more for "bulimia", whilst "anorexia" was searched in Hebrew only. When adjusting for confounding variables, association between digital seeking behavior and ethnicity remained statistically significant ( p -value < 0.0001) for all psychiatric disorders considered in the current investigation, except for "bulimia" ( p  = 0.989). More in details, Israeli Arabs searched for mental health disorders less than Jews, apart from "depression". Arab and Jewish Israelis, besides differing in terms of language, religion, social and cultural values, have different patterns of usage of healthcare services and provisions, as well as e-healthcare services concerning mental health. Policy- and decision-makers should be aware of this and make their best efforts to promote digital health literacy among the Arab population in Israel.

Searching the Internet for psychiatric disorders among Arab and Jewish Israelis: insights from a comprehensive infodemiological survey

PubMed Central

Adawi, Mohammad; Amital, Howard; Mahamid, Mahmud; Amital, Daniela; Bisharat, Bishara; Mahroum, Naim; Sharif, Kassem; Guy, Adi; Adawi, Amin; Mahagna, Hussein; Abu Much, Arsalan; Watad, Samaa; Watad, Abdulla

2018-01-01

Israel represents a complex and pluralistic society comprising two major ethno-national groups, Israeli Jews and Israeli Arabs, which differ in terms of religious and cultural values as well as social constructs. According to the so-called “diversification hypothesis”, within the framework of e-health and in the era of new information and communication technologies, seeking online health information could be a channel to increase health literacy, especially among disadvantaged groups. However, little is known concerning digital seeking behavior and, in particular, digital mental health literacy. This study was conducted in order to fill in this gap. Concerning raw figures, unadjusted for confounding variables (time, population size, Internet penetration index, disease rate), “depression” searched in Hebrew was characterized by 1.5 times higher search volumes, slightly declining throughout time, whereas relative search volumes (RSVs) related to “depression” searched in Arabic tended to increase over the years. Similar patterns could be detected for “phobia” (in Hebrew 1.4-fold higher than in Arabic) and for “anxiety” (with the searches performed in Hebrew 2.3 times higher than in Arabic). “Suicide” in Hebrew was searched 2.0-fold more than in Arabic (interestingly for both languages search volumes exhibited seasonal cyclic patterns). Eating disorders were searched more in Hebrew: 8.0-times more for “bulimia”, whilst “anorexia” was searched in Hebrew only. When adjusting for confounding variables, association between digital seeking behavior and ethnicity remained statistically significant (p-value < 0.0001) for all psychiatric disorders considered in the current investigation, except for “bulimia” (p = 0.989). More in details, Israeli Arabs searched for mental health disorders less than Jews, apart from “depression”. Arab and Jewish Israelis, besides differing in terms of language, religion, social and cultural values, have different patterns of usage of healthcare services and provisions, as well as e-healthcare services concerning mental health. Policy- and decision-makers should be aware of this and make their best efforts to promote digital health literacy among the Arab population in Israel. PMID:29576974

Telemedicine and its transformation of emergency care: a case study of one of the largest US integrated healthcare delivery systems.

PubMed

Sharma, Rahul; Fleischut, Peter; Barchi, Daniel

2017-12-01

Innovative methods for delivering healthcare via the use of technology are rapidly growing. Despite the passage of the Affordable Care Act, emergency department visits have continued to rise nationally. Healthcare systems must devise solutions to face these increasing volumes and also deliver high quality care. In response to the changing healthcare landscape, New York Presbyterian Hospital has implemented a comprehensive enterprise wide digital health portfolio which includes the first mobile stroke treatment unit on the east coast and the first emergency department-based digital emergency care program in New York City.

Partially filled electrodes for digital microfluidic devices

NASA Astrophysics Data System (ADS)

Pyne, D. G.; Salman, W. M.; Abdelgawad, M.; Sun, Y.

2013-07-01

As digital microfluidics technology evolves, the need for integrating additional elements (e.g., sensing/detection and heating elements) on the electrode increases. Consequently, electrode area for droplet actuation is reduced to create space for accommodating these additional elements, which undesirably affects force generation. Electrodes cannot simply be scaled larger to compensate for this loss of force, as this would also increase droplet volume and thereby compromise the advantages thought in miniaturization. Here, we present a study evaluating, numerically with preliminary experimental verification, different partially filled electrode designs and suggesting designs that combine high actuation forces with a large reduction in electrode area.

NIR light propagation in a digital head model for traumatic brain injury (TBI)

PubMed Central

Francis, Robert; Khan, Bilal; Alexandrakis, George; Florence, James; MacFarlane, Duncan

2015-01-01

Near infrared spectroscopy (NIRS) is capable of detecting and monitoring acute changes in cerebral blood volume and oxygenation associated with traumatic brain injury (TBI). Wavelength selection, source-detector separation, optode density, and detector sensitivity are key design parameters that determine the imaging depth, chromophore separability, and, ultimately, clinical usefulness of a NIRS instrument. We present simulation results of NIR light propagation in a digital head model as it relates to the ability to detect intracranial hematomas and monitor the peri-hematomal tissue viability. These results inform NIRS instrument design specific to TBI diagnosis and monitoring. PMID:26417498

FOCIS: A forest classification and inventory system using LANDSAT and digital terrain data

NASA Technical Reports Server (NTRS)

Strahler, A. H.; Franklin, J.; Woodcook, C. E.; Logan, T. L.

1981-01-01

Accurate, cost-effective stratification of forest vegetation and timber inventory is the primary goal of a Forest Classification and Inventory System (FOCIS). Conventional timber stratification using photointerpretation can be time-consuming, costly, and inconsistent from analyst to analyst. FOCIS was designed to overcome these problems by using machine processing techniques to extract and process tonal, textural, and terrain information from registered LANDSAT multispectral and digital terrain data. Comparison of samples from timber strata identified by conventional procedures showed that both have about the same potential to reduce the variance of timber volume estimates over simple random sampling.

Projection-based motion estimation for cardiac functional analysis with high temporal resolution: a proof-of-concept study with digital phantom experiment

NASA Astrophysics Data System (ADS)

Suzuki, Yuki; Fung, George S. K.; Shen, Zeyang; Otake, Yoshito; Lee, Okkyun; Ciuffo, Luisa; Ashikaga, Hiroshi; Sato, Yoshinobu; Taguchi, Katsuyuki

2017-03-01

Cardiac motion (or functional) analysis has shown promise not only for non-invasive diagnosis of cardiovascular diseases but also for prediction of cardiac future events. Current imaging modalities has limitations that could degrade the accuracy of the analysis indices. In this paper, we present a projection-based motion estimation method for x-ray CT that estimates cardiac motion with high spatio-temporal resolution using projection data and a reference 3D volume image. The experiment using a synthesized digital phantom showed promising results for motion analysis.

High-efficiency holograms fixed in lithium niobate after recording using a digital fringe stabilization system.

PubMed

Arizmendi, Luis; Ambite, Emilio J

2012-02-20

We used a digital feedback control loop system to produce reproducible fixed volume transmission holograms of high diffraction efficiency. Different strategies were investigated to obtain holograms of good quality and the highest refractive index modulation depth. Using this control system, we were able to record holograms with stationary fringes. Additionally to using the stationary fringe recording, a double recording-fixing schedule resulted in being the most appropriate one to produce reproducible holograms of better characteristics. This strategy is discussed and compared with other already established ones. © 2012 Optical Society of America

A Hydraulic Blowdown Servo System For Launch Vehicle

NASA Astrophysics Data System (ADS)

Chen, Anping; Deng, Tao

2016-07-01

This paper introduced a hydraulic blowdown servo system developed for a solid launch vehicle of the family of Chinese Long March Vehicles. It's the thrust vector control (TVC) system for the first stage. This system is a cold gas blowdown hydraulic servo system and consist of gas vessel, hydraulic reservoir, servo actuator, digital control unit (DCU), electric explosion valve, and pressure regulator etc. A brief description of the main assemblies and characteristics follows. a) Gas vessel is a resin/carbon fiber composite over wrapped pressure vessel with a titanium liner, The volume of the vessel is about 30 liters. b) Hydraulic reservoir is a titanium alloy piston type reservoir with a magnetostrictive sensor as the fluid level indicator. The volume of the reservoir is about 30 liters. c) Servo actuator is a equal area linear piston actuator with a 2-stage low null leakage servo valve and a linear variable differential transducer (LVDT) feedback the piston position, Its stall force is about 120kN. d) Digital control unit (DCU) is a compact digital controller based on digital signal processor (DSP), and deployed dual redundant 1553B digital busses to communicate with the on board computer. e) Electric explosion valve is a normally closed valve to confine the high pressure helium gas. f) Pressure regulator is a spring-loaded poppet pressure valve, and regulates the gas pressure from about 60MPa to about 24MPa. g) The whole system is mounted in the aft skirt of the vehicle. h) This system delivers approximately 40kW hydraulic power, by contrast, the total mass is less than 190kg. the power mass ratio is about 0.21. Have finished the development and the system test. Bench and motor static firing tests verified that all of the performances have met the design requirements. This servo system is complaint to use of the solid launch vehicle.

The use of optical waveguides in head up display (HUD) applications

NASA Astrophysics Data System (ADS)

Homan, Malcolm

2013-06-01

The application of optical waveguides to Head Up Displays (HUD) is an enabling technology which solves the critical issues of volume reduction (including cockpit intrusion) and mass reduction in an affordable product which retains the high performance optical capabilities associated with today's generation of digital display based HUDs. Improved operability and pilot comfort is achieved regardless of the installation by virtue of the intrinsic properties of optical waveguides and this has enabled BAE Systems Electronic Systems to develop two distinct product streams for glareshield and overhead HUD installations respectively. This paper addresses the design drivers behind the development of the next generation of Head Up Displays and their compatibility with evolving cockpit architectures and structures. The implementation of large scale optical waveguide combiners capable of matching and exceeding the display performances normally only associated with current digital display sourced HUDs has enabled BAE Systems Electronic Systems to solve the volume and installation challenges of the latest military and civil cockpits with it's LiteHUD® technology. Glareshield mounted waveguide based HUDs are compatible with the trend towards the addition of Large Area Displays (LAD) in place of the traditional multiple Head Down Displays (HDD) within military fast jet cockpits. They use an "indirect view" variant of the display which allows the amalgamation of high resolution digital display devices with the inherently small volume and low mass of the waveguide optics. This is then viewed using the more traditional technology of a conventional HUD combiner. This successful combination of technologies has resulted in the LPHUD product which is specifically designed by BAE Systems Electronic Systems to provide an ultra-low profile HUD which can be installed behind a LAD; still providing the level of performance that is at least equivalent to that of a conventional large volume glareshield mounted HUD. In many current Business Jet and Air Transport cockpits overhead mounted HUDs employ a conventional optical combiner to relay the display from a separate projector to the pilot's eyes. In BAE Systems' Electronic Systems QHUDTM configuration this combiner is replaced by the waveguide and the bulky, intrusive overhead projector completely eliminated. The result is a significant reduction in equipment volume and mass and a much greater head clearance combined with a substantially larger Head Motion Box. This latter feature is a fundamental outturn of waveguide optical solutions which removes the restrictions on pilot eye positioning associated with current conventional systems. LiteHUD®, developed by BAE Systems, Electronic Systems achieves equivalent optical performance to in-service HUDs for less cost, mass and volume.

The use of self-organising maps for anomalous behaviour detection in a digital investigation.

PubMed

Fei, B K L; Eloff, J H P; Olivier, M S; Venter, H S

2006-10-16

The dramatic increase in crime relating to the Internet and computers has caused a growing need for digital forensics. Digital forensic tools have been developed to assist investigators in conducting a proper investigation into digital crimes. In general, the bulk of the digital forensic tools available on the market permit investigators to analyse data that has been gathered from a computer system. However, current state-of-the-art digital forensic tools simply cannot handle large volumes of data in an efficient manner. With the advent of the Internet, many employees have been given access to new and more interesting possibilities via their desktop. Consequently, excessive Internet usage for non-job purposes and even blatant misuse of the Internet have become a problem in many organisations. Since storage media are steadily growing in size, the process of analysing multiple computer systems during a digital investigation can easily consume an enormous amount of time. Identifying a single suspicious computer from a set of candidates can therefore reduce human processing time and monetary costs involved in gathering evidence. The focus of this paper is to demonstrate how, in a digital investigation, digital forensic tools and the self-organising map (SOM)--an unsupervised neural network model--can aid investigators to determine anomalous behaviours (or activities) among employees (or computer systems) in a far more efficient manner. By analysing the different SOMs (one for each computer system), anomalous behaviours are identified and investigators are assisted to conduct the analysis more efficiently. The paper will demonstrate how the easy visualisation of the SOM enhances the ability of the investigators to interpret and explore the data generated by digital forensic tools so as to determine anomalous behaviours.

High-volume optical vortex multiplexing and de-multiplexing for free-space optical communication.

PubMed

Wang, Zhongxi; Zhang, N; Yuan, X-C

2011-01-17

We report an approach to the increase of signal channels in free-space optical communication based on composed optical vortices (OVs). In the encoding process, conventional algorithm employed for the generation of collinearly superimposed OVs is combined with a genetic algorithm to achieve high-volume OV multiplexing. At the receiver end, a novel Dammann vortex grating is used to analyze the multihelix beams with a large number of OVs. We experimentally demonstrate a digitized system which is capable of transmitting and receiving 16 OV channels simultaneously. This system is expected to be compatible with a high-speed OV multiplexing technique, with potentials to extremely high-volume information density in OV communication.

Development of computerized stocktaking system in mine surveying for ore mineral volume calculation in covered storehouses

NASA Astrophysics Data System (ADS)

Valdman, V. V.; Gridnev, S. O.

2017-10-01

The article examines into the vital issues of measuring and calculating the raw stock volumes in covered storehouses at mining and processing plants. The authors bring out two state-of-the-art high-technology solutions: 1 - to use the ground-based laser scanning system (the method is reasonably accurate and dependable, but costly and time consuming; it also requires the stoppage of works in the storehouse); 2 - to use the fundamentally new computerized stocktaking system in mine surveying for the ore mineral volume calculation, based on the profile digital images. These images are obtained via vertical projection of the laser plane onto the surface of the stored raw materials.

Spatial distribution of erosion and deposition during a glacier surge: Brúarjökull, Iceland

NASA Astrophysics Data System (ADS)

Korsgaard, Niels J.; Schomacker, Anders; Benediktsson, Ívar Örn; Larsen, Nicolaj K.; Ingólfsson, Ólafur; Kjær, Kurt H.

2015-12-01

Time-series of digital elevation models (DEMs) of the forefield of the Brúarjökull surge-type glacier in Iceland were used to quantify the volume of material that was mobilized by the 1963-1964 surge. The DEMs were produced by stereophotogrammetry on aerial photographs from before the surge (1961) and after (1988 and 2003). The analysis was performed on two DEMs of Difference (DoDs), i.e., a 1961-2003 DoD documenting the impact of the surge and a 1988-2003 DoD documenting the post-surge modification of the juvenile surging glacier landsystem. Combined with a digital geomorphological map, the DoDs allow us to quantify the impact of the surge on a landsystem scale down to individual landforms. A total of 34.2 ± 11.3 × 106 m3 of material was mobilized in the 30.7-km2 study area as a result of the most recent surge event. Of these, 17.4 ± 6.6 × 106 m3 of the material were eroded and 16.8 ± 4.7 × 106 m3 were deposited. More than half of the deposited volume was ice-cored landforms. This study demonstrates that although the total mobilized mass volume is high, the net volume gain of ice and sediment deposited as landforms in the forefield caused by the surge is low. Furthermore, deposition of new dead-ice from the 1963-1964 surge constitutes as much as 64% of the volume gain in the forefield. The 1988-2003 DoD is used to quantify the melt-out of this dead-ice and other paraglacial modification of the recently deglaciated forefield of Brúarjökull.

A simple formula for predicting claw volume of cattle.

PubMed

Scott, T D; Naylor, J M; Greenough, P R

1999-11-01

The object of this study was to develop a simple method for accurately calculating the volume of bovine claws under field conditions. The digits of 30 slaughterhouse beef cattle were examined and the following four linear measurements taken from each pair of claws: (1) the length of the dorsal surface of the claw (Toe); (2) the length of the coronary band (CorBand); (3) the length of the bearing surface (Base); and (4) the height of the claw at the abaxial groove (AbaxGr). Measurements of claw volume using a simple hydrometer were highly repeatable (r(2)= 0.999) and could be calculated from linear measurements using the formula:Claw Volume (cm(3)) = (17.192 x Base) + (7.467 x AbaxGr) + 45.270 x (CorBand) - 798.5This formula was found to be accurate (r(2)= 0.88) when compared to volume data derived from a hydrometer displacement procedure. The front claws occupied 54% of the total volume compared to 46% for the hind claws. Copyright 1999 Harcourt Publishers Ltd.

Calculation of Lung Cancer Volume of Target Based on Thorax Computed Tomography Images using Active Contour Segmentation Method for Treatment Planning System

NASA Astrophysics Data System (ADS)

Patra Yosandha, Fiet; Adi, Kusworo; Edi Widodo, Catur

2017-06-01

In this research, calculation process of the lung cancer volume of target based on computed tomography (CT) thorax images was done. Volume of the target calculation was done in purpose to treatment planning system in radiotherapy. The calculation of the target volume consists of gross tumor volume (GTV), clinical target volume (CTV), planning target volume (PTV) and organs at risk (OAR). The calculation of the target volume was done by adding the target area on each slices and then multiply the result with the slice thickness. Calculations of area using of digital image processing techniques with active contour segmentation method. This segmentation for contouring to obtain the target volume. The calculation of volume produced on each of the targets is 577.2 cm3 for GTV, 769.9 cm3 for CTV, 877.8 cm3 for PTV, 618.7 cm3 for OAR 1, 1,162 cm3 for OAR 2 right, and 1,597 cm3 for OAR 2 left. These values indicate that the image processing techniques developed can be implemented to calculate the lung cancer target volume based on CT thorax images. This research expected to help doctors and medical physicists in determining and contouring the target volume quickly and precisely.

IRIT at TREC 2012 Contextual Suggestion Track

DTIC Science & Technology

2012-11-01

the 2nd International Conference on Software and Data Technologies, volume 3, pages 166–171. INSTICC Press, 2007. [HM09] Gilles Hubert and Josiane...geographic information retrieval systems: Evaluation framework and case study. Int. J. Digit. Libr ., pages 91–109, 2010. [PSC+12] Damien Palacio, Christian

Air Force Tech Order Management System (AFTOMS). Automation Plan-Final Report. Version 1.0

DOT National Transportation Integrated Search

1988-02-01

Computer aided Acquisition and Logistics Support (CALS) is a Department of Defense (DoD) program designed to improve weapon systems support through digital automation. In June 1985, the joint industry/DoD Task Force on CALS issued a five volume repor...

Air Traffic Control Experimentation and Evaluation with the NASA ATS-6 Satellite : Volume 4. Data Reduction and Analysis Software.

DOT National Transportation Integrated Search

1976-09-01

Software used for the reduction and analysis of the multipath prober, modem evaluation (voice, digital data, and ranging), and antenna evaluation data acquired during the ATS-6 field test program is described. Multipath algorithms include reformattin...

A Tight Squeeze

ERIC Educational Resources Information Center

Ramaswami, Rama

2008-01-01

The Storage Networking Industry Association (SNIA) does not mince words when describing the looming data storage problem. In its 2007 report, "Solving the Coming Archive Crisis--the 100-Year Dilemma," the trade group asserts that the volume of disparate digital information sources being kept online for long-term preservation is overwhelming and…

The combined effect of mammographic texture and density on breast cancer risk: a cohort study.

PubMed

Wanders, Johanna O P; van Gils, Carla H; Karssemeijer, Nico; Holland, Katharina; Kallenberg, Michiel; Peeters, Petra H M; Nielsen, Mads; Lillholm, Martin

2018-05-02

Texture patterns have been shown to improve breast cancer risk segregation in addition to area-based mammographic density. The additional value of texture pattern scores on top of volumetric mammographic density measures in a large screening cohort has never been studied. Volumetric mammographic density and texture pattern scores were assessed automatically for the first available digital mammography (DM) screening examination of 51,400 women (50-75 years of age) participating in the Dutch biennial breast cancer screening program between 2003 and 2011. The texture assessment method was developed in a previous study and validated in the current study. Breast cancer information was obtained from the screening registration system and through linkage with the Netherlands Cancer Registry. All screen-detected breast cancers diagnosed at the first available digital screening examination were excluded. During a median follow-up period of 4.2 (interquartile range (IQR) 2.0-6.2) years, 301 women were diagnosed with breast cancer. The associations between texture pattern scores, volumetric breast density measures and breast cancer risk were determined using Cox proportional hazard analyses. Discriminatory performance was assessed using c-indices. The median age of the women at the time of the first available digital mammography examination was 56 years (IQR 51-63). Texture pattern scores were positively associated with breast cancer risk (hazard ratio (HR) 3.16 (95% CI 2.16-4.62) (p value for trend <0.001), for quartile (Q) 4 compared to Q1). The c-index of texture was 0.61 (95% CI 0.57-0.64). Dense volume and percentage dense volume showed positive associations with breast cancer risk (HR 1.85 (95% CI 1.32-2.59) (p value for trend <0.001) and HR 2.17 (95% CI 1.51-3.12) (p value for trend <0.001), respectively, for Q4 compared to Q1). When adding texture measures to models with dense volume or percentage dense volume, c-indices increased from 0.56 (95% CI 0.53-0.59) to 0.62 (95% CI 0.58-0.65) (p < 0.001) and from 0.58 (95% CI 0.54-0.61) to 0.60 (95% CI 0.57-0.63) (p = 0.054), respectively. Deep-learning-based texture pattern scores, measured automatically on digital mammograms, are associated with breast cancer risk, independently of volumetric mammographic density, and augment the capacity to discriminate between future breast cancer and non-breast cancer cases.

Nuclear Science Symposium, 23rd, Scintillation and Semiconductor Counter Symposium, 15th, and Nuclear Power Systems Symposium, 8th, New Orleans, La., October 20-22, 1976, Proceedings

NASA Technical Reports Server (NTRS)

Wagner, L. J.

1977-01-01

The volume includes papers on semiconductor radiation detectors of various types, components of radiation detection and dosimetric systems, digital and microprocessor equipment in nuclear industry and science, and a wide variety of applications of nuclear radiation detectors. Semiconductor detectors of X-rays, gamma radiation, heavy ions, neutrons, and other nuclear particles, plastic scintillator arrays, drift chambers, spark wire chambers, and radiation dosimeter systems are reported on. Digital and analog conversion systems, digital data and control systems, microprocessors, and their uses in scientific research and nuclear power plants are discussed. Large-area imaging and biomedical nucleonic instrumentation, nuclear power plant safeguards, reactor instrumentation, nuclear power plant instrumentation, space instrumentation, and environmental instrumentation are dealt with. Individual items are announced in this issue.

Measuring opto-thermal parameters of basalt fibers using digital holographic microscopy.

PubMed

Yassien, Khaled M; Agour, Mostafa

2017-02-01

A method for studying the effect of temperature on the optical properties of basalt fiber is presented. It is based on recording a set of phase-shifted digital holograms for the sample under the test. The holograms are obtained utilizing a system based on Mach-Zehnder interferometer, where the fiber sample inserted in an immersion liquid is placed within a temperature controlled chamber. From the recorded digital holograms the optical path differences which are used to calculate the refractive indices are determined. The accuracy in the measurement of refractive indices is in the range of 4 × 10 -4 . The influence of temperature on the dispersion parameters, polarizability per unit volume and dielectric susceptibility are also obtained. Moreover, the values of dispersion and oscillation energies and Cauchy's constants are provided at different temperatures. © 2016 Wiley Periodicals, Inc.

Further development and testing of the metabolic gas analyzer

NASA Technical Reports Server (NTRS)

1973-01-01

Continued development of a metabolic monitor utilizing a mass spectrometer and digital computer to perform measurements and data reduction, is reported. The device prints-out breath-by-breath values for 02 consumption, C02 production, minute volume and tidal volume. The flow is measured by introduction of a tracer gas to the expired gas stream. Design modifications to reduce pressure drop in the flow splitter to one inch of water at 600 liters/min flow and to extend the range of linear flow measurement to 1000 liters/min are discussed.

Computer program to perform cost and weight analysis of transport aircraft. Volume 2: Technical volume

NASA Technical Reports Server (NTRS)

1973-01-01

An improved method for estimating aircraft weight and cost using a unique and fundamental approach was developed. The results of this study were integrated into a comprehensive digital computer program, which is intended for use at the preliminary design stage of aircraft development. The program provides a means of computing absolute values for weight and cost, and enables the user to perform trade studies with a sensitivity to detail design and overall structural arrangement. Both batch and interactive graphics modes of program operation are available.

Surface structural damage study in cortical bone due to medical drilling.

PubMed

Tavera R, Cesar G; De la Torre-I, Manuel H; Flores-M, Jorge M; Hernandez M, Ma Del Socorro; Mendoza-Santoyo, Fernando; Briones-R, Manuel de J; Sanchez-P, Jorge

2017-05-01

A bone's fracture could be produced by an excessive, repetitive, or sudden load. A regular medical practice to heal it is to fix it in two possible ways: external immobilization, using a ferule, or an internal fixation, using a prosthetic device commonly attached to the bone by means of surgical screws. The bone's volume loss due to this drilling modifies its structure either in the presence or absence of a fracture. To observe the bone's surface behavior caused by the drilling effects, a digital holographic interferometer is used to analyze the displacement surface's variations in nonfractured post-mortem porcine femoral bones. Several nondrilled post-mortem bones are compressed and compared to a set of post-mortem bones with a different number of cortical drillings. During each compression test, a series of digital interferometric holograms were recorded using a high-speed CMOS camera. The results are presented as pseudo 3D mesh displacement maps for comparisons in the physiological range of load (30 and 50 lbs) and beyond (100, 200, and 400 lbs). The high resolution of the optical phase gives a better understanding about the bone's microstructural modifications. Finally, a relationship between compression load and bone volume loss due to the drilling was observed. The results prove that digital holographic interferometry is a viable technique to study the conditions that avoid the surgical screw from loosening in medical procedures of this kind.

[Infoxication in health. Health information overload on the Internet and the risk of important information becoming invisible].

PubMed

D Agostino, Marcelo; Mejía, Felipe Medina; Martí, Myrna; Novillo-Ortiz, David; Hazrum, Flavio; de Cosío, Federico G

2018-02-19

The objectives of this study were to: 1) raise awareness of the volume of quality health information on the Internet; 2) explore perceptions of information professionals with regard to the use of qualified sources for health decision-making; and 3) make recommendations that facilitate strengthening health worker capacities and institutional competencies related to digital literacy. A non-experimental, descriptive cross-sectional study was conducted with a non-probability sample of 32 information professionals from nine countries. Internet information was compiled on the volume of content in Internet tools, social networks, and health information sources. Searches in English and Spanish were carried out using the keywords Ebola, Zika, dengue, chikungunya, safe food, health equity, safe sex, and obesity. Finally, information was obtained on opportunities for formal education on the subjects of digital literacy, information management, and other related topics. Selecting only four diseases with a high impact on public health in May 2016 and averaging minimum review time for each information product, it would take more than 50 years without sleeping to consult everything that is published online about dengue, Zika, Ebola, and chikungunya. We conclude that public health would benefit from: health institutions implementing formal knowledge management strategies; academic health sciences institutions incorporating formal digital literacy programs; and having health workers who are professionally responsible and functional in the information society.

Comparison of computed radiography and conventional radiography in detection of small volume pneumoperitoneum.

PubMed

Marolf, Angela; Blaik, Margaret; Ackerman, Norman; Watson, Elizabeth; Gibson, Nicole; Thompson, Margret

2008-01-01

The role of digital imaging is increasing as these systems are becoming more affordable and accessible. Advantages of computed radiography compared with conventional film/screen combinations include improved contrast resolution and postprocessing capabilities. Computed radiography's spatial resolution is inferior to conventional radiography; however, this limitation is considered clinically insignificant. This study prospectively compared digital imaging and conventional radiography in detecting small volume pneumoperitoneum. Twenty cadaver dogs (15-30 kg) were injected with 0.25, 0.25, and 0.5 ml for 1 ml total of air intra-abdominally, and radiographed sequentially using computed and conventional radiographic technologies. Three radiologists independently evaluated the images, and receiver operating curve (ROC) analysis compared the two imaging modalities. There was no statistical difference between computed and conventional radiography in detecting free abdominal air, but overall computed radiography was relatively more sensitive based on ROC analysis. Computed radiographic images consistently and significantly demonstrated a minimal amount of 0.5 ml of free air based on ROC analysis. However, no minimal air amount was consistently or significantly detected with conventional film. Readers were more likely to detect free air on lateral computed images than the other projections, with no significant increased sensitivity between film/screen projections. Further studies are indicated to determine the differences or lack thereof between various digital imaging systems and conventional film/screen systems.

Digital holographic microscopy combined with optical tweezers

NASA Astrophysics Data System (ADS)

Cardenas, Nelson; Yu, Lingfeng; Mohanty, Samarendra K.

2011-02-01

While optical tweezers have been widely used for the manipulation and organization of microscopic objects in three dimensions, observing the manipulated objects along axial direction has been quite challenging. In order to visualize organization and orientation of objects along axial direction, we report development of a Digital holographic microscopy combined with optical tweezers. Digital holography is achieved by use of a modified Mach-Zehnder interferometer with digital recording of interference pattern of the reference and sample laser beams by use of a single CCD camera. In this method, quantitative phase information is retrieved dynamically with high temporal resolution, only limited by frame rate of the CCD. Digital focusing, phase-unwrapping as well as online analysis and display of the quantitative phase images was performed on a software developed on LabView platform. Since phase changes observed in DHOT is very sensitive to optical thickness of trapped volume, estimation of number of particles trapped in the axial direction as well as orientation of non-spherical objects could be achieved with high precision. Since in diseases such as malaria and diabetics, change in refractive index of red blood cells occurs, this system can be employed to map such disease-specific changes in biological samples upon immobilization with optical tweezers.

Application of computerized exercise ECG digitization. Interpretation in large clinical trials.

PubMed

Caralis, D G; Shaw, L; Bilgere, B; Younis, L; Stocke, K; Wiens, R D; Chaitman, B R

1992-04-01

The authors report on a semiautomated program that incorporates both visual identification of fiducial points and digital determination of the ST-segment at 60 ms and 80 ms from the J point, ST slope, changes in R wave, and baseline drift. The off-line program can enhance the accuracy of detecting electrocardiographic (ECG) changes, as well as reproducibility of the exercise and postexercise ECG, as a marker of myocardial ischemia. The analysis program is written in Microsoft QuickBASIC 2.0 for an IBM personal computer interfaced to a Summagraphics mm1201 microgrid II digitizer. The program consists of the following components: (1) alphanumeric data entry, (2) ECG wave form digitization, (2) calculation of test results, (4) physician overread, and (5) editor function for remeasurements. This computerized exercise ECG digitization-interpretation program is accurate and reproducible for the quantitative assessment of ST changes and requires minimal time allotment for physician overread. The program is suitable for analysis and interpretation of large volumes of exercise tests in multicenter clinical trials and is currently utilized in the TIMI II, TIMI III, and BARI studies sponsored by the National Institutes of Health.

User centered design of the digital book: why looking backward can help us move forward

NASA Astrophysics Data System (ADS)

Wallis, Jillian C.

2006-02-01

What is emerging from the digital book revolution is a state of technology that has brought new affordances to the book, such as search, hyperlinking, personalization, dynamic content, 24/7 access, automated indexing and summarizing, aggregated content, and new modes of reading and access. These could solve some of the issues users have with the static content of traditional bound volumes, but the technology so far has staunchly ignored the tried and true technologies of books, such as infinite resolution, high contrast, low glare, haptic navigation, typographic niceties, and the rights of first sale to borrow, lend, or resell a work. By exploring a survey of literature, reviews, and user tests, I intend to address the point of how the current concept of the digital book is an inappropriate tool for the user and the task of reading, and as a result not been enthusiastically embraced by the market. The collected evidence indicates that it is impossible to forget our past in our quest for the future, and that technology can help us to unite the disparate realities of analog and digital to create a truly digital book.

Three dimensional digital reconstruction of the jaw adductor musculature of the extinct marsupial giant Diprotodon optatum

PubMed Central

2014-01-01

The morphology and arrangement of the jaw adductor muscles in vertebrates reflects masticatory style and feeding processes, diet and ecology. However, gross muscle anatomy is rarely preserved in fossils and is, therefore, heavily dependent on reconstructions. An undeformed skull of the extinct marsupial, Diprotodon optatum, recovered from Pleistocene sediments at Bacchus Marsh in Victoria, represents the most complete and best preserved specimen of the species offering a unique opportunity to investigate functional anatomy. Computed tomography (CT) scans and digital reconstructions make it possible to visualise internal cranial anatomy and predict location and morphology of soft tissues, including muscles. This study resulted in a 3D digital reconstruction of the jaw adductor musculature of Diprotodon, revealing that the arrangement of muscles is similar to that of kangaroos and that the muscle actions were predominantly vertical. 3D digital muscle reconstructions provide considerable advantages over 2D reconstructions for the visualisation of the spatial arrangement of the individual muscles and the measurement of muscle properties (length, force vectors and volume). Such digital models can further be used to estimate muscle loads and attachment sites for biomechanical analyses. PMID:25165628

SCAR Radiologic Technologist Survey: analysis of technologist workforce and staffing.

PubMed

Reiner, Bruce; Siegel, Eliot; Carrino, John A; McElveny, Ceela

2002-09-01

One of the greatest dilemmas facing medical imaging departments today is the worsening personnel crisis in the radiologic technologist (RT) workforce. As the volume and complexity of medical imaging studies continues to increase, an unprecedented imbalance exists between RT supply and demand. A number of etiologic factors have been postulated to contribute to this RT shortage including decreasing morale, perceived inadequacies in compensation, decreasing number of training programs, and limitations in the career ladder. Previous studies have cited improved technologist productivity as imaging departments successfully transition from film-based to filmless operation. This study was undertaken to address the impact of digital technologies (information systems, PACS, digital radiography) on technologist productivity, in an attempt to determine whether these technologies can be used to positively affect the existing RT workforce imbalance. A total of 112 facilities participated in this nationwide study, with representation of imaging providers that paralleled the demographic profile of the marketplace as a whole. Survey results indicate the existing RT staffing shortage is greatest within academic and rural-based hospitals and is most severe in the area of general radiography, which accounts for 65-70% of imaging department volumes. For general radiography alone, respondents report an average shortage of 2 RT full-time equivalents (FTE's) per institution, when comparing the number of budgeted RT FTE's versus the actual number of RT FTE's. Preliminary results indicate that at this time, RT staffing shortages are not affected by the presence or absence of digital information technologies. Additional research is planned through a five-year longitudinal data collection, to better delineate the complex relationship that exists between implementation of digital technologies and RT staffing.

Current and future industrial energy service characterizations. Volume III. Energy data on 15 selected states' manufacturing subsector

DOE Office of Scientific and Technical Information (OSTI.GOV)

Krawiec, F.; Thomas, T.; Jackson, F.

1980-11-01

An examination is made of the current and future energy demands, and uses, and cost to characterize typical applications and resulting services in the US and industrial sectors of 15 selected states. Volume III presents tables containing data on selected states' manufacturing subsector energy consumption, functional uses, and cost in 1974 and 1976. Alabama, California, Illinois, Indiana, Louisiana, Michigan, Missouri, New Jersey, New York, Ohio, Oregon, Pennsylvania, Texas, West Virginia, and Wisconsin were chosen as having the greatest potential for replacing conventional fuel with solar energy. Basic data on the quantities, cost, and types of fuel and electric energy purchasedmore » by industr for heat and power were obtained from the 1974 and 1976 Annual Survey of Manufacturers. The specific indutrial energy servic cracteristics developed for each selected state include. 1974 and 1976 manufacturing subsector fuels and electricity consumption by 2-, 3-, and 4-digit SIC and primary fuel (quantity and relative share); 1974 and 1976 manufacturing subsector fuel consumption by 2-, 3-, and 4-digit SIC and primary fuel (quantity and relative share); 1974 and 1976 manufacturing subsector average cost of purchsed fuels and electricity per million Btu by 2-, 3-, and 4-digit SIC and primary fuel (in 1976 dollars); 1974 and 1976 manufacturing subsector fuels and electric energy intensity by 2-, 3-, and 4-digit SIC and primary fuel (in 1976 dollars); manufacturing subsector average annual growth rates of (1) fuels and electricity consumption, (2) fuels and electric energy intensity, and (3) average cost of purchased fuels and electricity (1974 to 1976). Data are compiled on purchased fuels, distillate fuel oil, residual ful oil, coal, coal, and breeze, and natural gas. (MCW)« less

Effects of Peripapillary Scleral Stiffening on the Deformation of the Lamina Cribrosa

PubMed Central

Coudrillier, Baptiste; Campbell, Ian C.; Read, A. Thomas; Geraldes, Diogo M.; Vo, Nghia T.; Feola, Andrew; Mulvihill, John; Albon, Julie; Abel, Richard L.; Ethier, C. Ross

2016-01-01

Purpose Scleral stiffening has been proposed as a treatment for glaucoma to protect the lamina cribrosa (LC) from excessive intraocular pressure–induced deformation. Here we experimentally evaluated the effects of moderate stiffening of the peripapillary sclera on the deformation of the LC. Methods An annular sponge, saturated with 1.25% glutaraldehyde, was applied to the external surface of the peripapillary sclera for 5 minutes to stiffen the sclera. Tissue deformation was quantified in two groups of porcine eyes, using digital image correlation (DIC) or computed tomography imaging and digital volume correlation (DVC). In group A (n = 14), eyes were subjected to inflation testing before and after scleral stiffening. Digital image correlation was used to measure scleral deformation and quantify the magnitude of scleral stiffening. In group B (n = 5), the optic nerve head region was imaged using synchrotron radiation phase-contrast microcomputed tomography (PC μCT) at an isotropic spatial resolution of 3.2 μm. Digital volume correlation was used to compute the full-field three-dimensional deformation within the LC and evaluate the effects of peripapillary scleral cross-linking on LC biomechanics. Results On average, scleral treatment with glutaraldehyde caused a 34 ± 14% stiffening of the peripapillary sclera measured at 17 mm Hg and a 47 ± 12% decrease in the maximum tensile strain in the LC measured at 15 mm Hg. The reduction in LC strains was not due to cross-linking of the LC. Conclusions Peripapillary scleral stiffening is effective at reducing the magnitude of biomechanical strains within the LC. Its potential and future utilization in glaucoma axonal neuroprotection requires further investigation. PMID:27183053

Space data management at the NSSDC (National Space Sciences Data Center): Applications for data compression

NASA Technical Reports Server (NTRS)

Green, James L.

1989-01-01

The National Space Science Data Center (NSSDC), established in 1966, is the largest archive for processed data from NASA's space and Earth science missions. The NSSDC manages over 120,000 data tapes with over 4,000 data sets. The size of the digital archive is approximately 6,000 gigabytes with all of this data in its original uncompressed form. By 1995 the NSSDC digital archive is expected to more than quadruple in size reaching over 28,000 gigabytes. The NSSDC digital archive is expected to more than quadruple in size reaching over 28,000 gigabytes. The NSSDC is beginning several thrusts allowing it to better serve the scientific community and keep up with managing the ever increasing volumes of data. These thrusts involve managing larger and larger amounts of information and data online, employing mass storage techniques, and the use of low rate communications networks to move requested data to remote sites in the United States, Europe and Canada. The success of these thrusts, combined with the tremendous volume of data expected to be archived at the NSSDC, clearly indicates that innovative storage and data management solutions must be sought and implemented. Although not presently used, data compression techniques may be a very important tool for managing a large fraction or all of the NSSDC archive in the future. Some future applications would consist of compressing online data in order to have more data readily available, compress requested data that must be moved over low rate ground networks, and compress all the digital data in the NSSDC archive for a cost effective backup that would be used only in the event of a disaster.

Integrated chemical/biochemical sample collection, pre-concentration, and analysis on a digital microfluidic lab-on-a-chip platform

NASA Astrophysics Data System (ADS)

Fair, Richard B.; Khlystov, A.; Srinivasan, Vijay; Pamula, Vamsee K.; Weaver, Kathryn N.

2004-12-01

An ideal on-site chemical/biochemical analysis system must be inexpensive, sensitive, fully automated and integrated, reliable, and compatible with a broad range of samples. The advent of digital microfluidic lab-on-a-chip (LoC) technology offers such a detection system due to the advantages in portability, reduction of the volumes of the sample and reagents, faster analysis times, increased automation, low power consumption, compatibility with mass manufacturing, and high throughput. We describe progress towards integrating sample collection onto a digital microfluidic LoC that is a component of a cascade impactor device. The sample collection is performed by impacting airborne particles directly onto the surface of the chip. After the collection phase, the surface of the chip is washed with a micro-droplet of solvent. The droplet will be digitally directed across the impaction surface, dissolving sample constituents. Because of the very small droplet volume used for extraction of the sample from a wide colection area, the resulting solution is realatively concentrated and the analytes can be detected after a very short sampling time (1 min) due to such pre-concentration. After the washing phase, the droplet is mixed with specific reagents that produce colored reaction products. The concentration of the analyte is quantitatively determined by measuring absorption at target wavelengths using a simple light emitting diode and photodiode setup. Specific applications include automatic measurements of major inorganic ions in aerosols, such as sulfate, nitrate and ammonium, with a time resolution of 1 min and a detection limit of 30 nm/m3. We have already demonstrated the detection and quantification of nitroaromatic explosives without integrating the sample collection. Other applications being developed include airborne bioagent detection.

A modified ATI technique for nowcasting convective rain volumes over areas. [area-time integrals

NASA Technical Reports Server (NTRS)

Makarau, Amos; Johnson, L. Ronald; Doneaud, Andre A.

1988-01-01

This paper explores the applicability of the area-time-integral (ATI) technique for the estimation of the growth portion only of a convective storm (while the rain volume is computed using the entire life history of the event) and for nowcasting the total rain volume of a convective system at the stage of its maximum development. For these purposes, the ATIs were computed from the digital radar data (for 1981-1982) from the North Dakota Cloud Modification Project, using the maximum echo area (ATIA) no less than 25 dBz, the maximum reflectivity, and the maximum echo height as the end of the growth portion of the convective event. Linear regression analysis demonstrated that correlations between total rain volume or the maximum rain volume versus ATIA were the strongest. The uncertainties obtained were comparable to the uncertainties which typically occur in rain volume estimates obtained from radar data employing Z-R conversion followed by space and time integration. This demonstrates that the total rain volume of a storm can be nowcasted at its maximum stage of development.

Microfluidic devices for the controlled manipulation of small volumes

DOEpatents

Ramsey, Michael J; Jacobson, Stephen C

2012-09-18

A method for conducting a broad range of biochemical analyses or manipulations on a series of nano- to subnanoliter reaction volumes and an apparatus for carrying out the same are disclosed. The invention is implemented on a fluidic microchip to provide high serial throughput. In particular, the disclosed device is a microfabricated channel device that can manipulate nanoliter or subnanoliter reaction volumes in a controlled manner to produce results at rates of 1 to 10 Hz per channel. The reaction volumes are manipulated in serial fashion analogous to a digital shift register. The invention has application to such problems as screening molecular or cellular targets using single beads from split-synthesis combinatorial libraries, screening single cells for RNA or protein expression, genetic diagnostic screening at the single cell level, or performing single cell signal transduction studies.

Chiral crossover transition in a finite volume

NASA Astrophysics Data System (ADS)

Shi, Chao; Jia, Wenbao; Sun, An; Zhang, Liping; Zong, Hongshi

2018-02-01

Finite volume effects on the chiral crossover transition of strong interactions at finite temperature are studied by solving the quark gap equation within a cubic volume of finite size L. With the anti-periodic boundary condition, our calculation shows the chiral quark condensate, which characterizes the strength of dynamical chiral symmetry breaking, decreases as L decreases below 2.5 fm. We further study the finite volume effects on the pseudo-transition temperature {T}{{c}} of the crossover, showing a significant decrease in {T}{{c}} as L decreases below 3 fm. Supported by National Natural Science Foundation of China (11475085, 11535005, 11690030, 51405027), the Fundamental Research Funds for the Central Universities (020414380074), China Postdoctoral Science Foundation (2016M591808) and Open Research Foundation of State Key Lab. of Digital Manufacturing Equipment & Technology in Huazhong University of Science & Technology (DMETKF2015015)

Microfluidic devices for the controlled manipulation of small volumes

DOEpatents

Ramsey, J Michael [Knoxville, TN; Jacobson, Stephen C [Knoxville, TN

2007-07-03

A method for conducting a broad range of biochemical analyses or manipulations on a series of nano- to subnanoliter reaction volumes and an apparatus for carrying out the same are disclosed. The invention is implemented on a fluidic microchip to provide high serial throughput. In particular, the disclosed device is a microfabricated channel device that can manipulate nanoliter or subnanoliter reaction volumes in a controlled manner to produce results at rates of 1 to 10 Hz per channel. The reaction volumes are manipulated in serial fashion analogous to a digital shift register. The invention has application to such problems as screening molecular or cellular targets using single beads from split-synthesis combinatorial libraries, screening single cells for RNA or protein expression, genetic diagnostic screening at the single cell level, or performing single cell signal transduction studies.

Vectored Thrust Digital Flight Control for Crew Escape. Volume 2.

DTIC Science & Technology

1985-12-01

no. 24. Lecrique, J., A. Rault, M. Tessier and J.L. Testud (1978), - "Multivariable Regulation of a Thermal Power Plant Steam Generator," presented...and Extended Kalman Observers," presented at the Conf. Decision and Control, San Diego, CA. Testud , J.L. (1977), Commande Numerique Multivariable du

Saliency-aware food image segmentation for personal dietary assessment using a wearable computer

USDA-ARS?s Scientific Manuscript database

Image-based dietary assessment has recently received much attention in the community of obesity research. In this assessment, foods in digital pictures are specified, and their portion sizes (volumes) are estimated. Although manual processing is currently the most utilized method, image processing h...

Personalisation of Generic Library Search Results Using Student Enrolment Information

ERIC Educational Resources Information Center

Alaofi, Marwah; Rumantir, Grace

2015-01-01

This research explores the application of implicit personalisation techniques in information retrieval in the context of education. Motivated by the large and ever-growing volume of resources in digital libraries, coupled with students' limited experience in searching for these resources, particularly in translating their information needs into…

Hammersmith cardiology workshop series. Volume 2

DOE Office of Scientific and Technical Information (OSTI.GOV)

Maseri, A.

1985-01-01

This book contains over 30 selections. Some of the titles are: Digital Subtraction Angiography: The Optimal Radiologic Technique for Cardiac Diagnosis; NMR Imaging of the Heart; Radioisotopes in the Evaluation of Right and Left Ventricular Function; Role of Membrane Abnormalities in the Pathogenesis of Heart Disease; and Influence of Arrhythmias on Cardiac Function.

Air Traffic Control Experimentation and Evaluation with the NASA ATS-6 Satellite : Volume 6. Modem Evaluation Test

DOT National Transportation Integrated Search

1976-09-01

Results of performance evaluation of voice, digital data and ranging modems in the aeronautical satellite environment are given. Approximately 80 hours of modem performance data were acquired on board an FAA KC-135 jet aircraft operating over the Nor...

Electronic Computer and Switching Systems Specialist (AFSC 30554).

ERIC Educational Resources Information Center

Air Univ., Gunter AFS, Ala. Extension Course Inst.

This course is intended to train Air Force personnel to become electronic computer and switching systems specialists. One part of the course consists of a three-volume career development course. Topics are maintenance orientation (15 hours), electronic principles and digital techniques (87 hours), and systems maintenance (51 hours). Each volume…

Multimodal Composing in Classrooms: Learning and Teaching for the Digital World

ERIC Educational Resources Information Center

Miller, Suzanne M., Ed.; McVee, Mary B., Ed.

2012-01-01

Taking a close look at multimodal composing as an essential new literacy in schools, this volume draws from contextualized case studies across educational contexts to provide detailed portraits of teachers and students at work in classrooms. Authors elaborate key issues in transforming classrooms with student multimodal composing, including…

PTC Mid Year Seminar. Collection of Presentations (Yokohama, Japan, June 3-4, 1997).

ERIC Educational Resources Information Center

Ando, Takatoshi

This proceedings volume from the Pacific Telecommunications Council Mid-Year Seminar includes the following presentations: "Platform and Equipment for Access Network" (Yukou Mochida); "Integrated Services Television: Digital Age TV with a Built-in Home Server" (Tatsuhito Nagaya); "Future of the Internet: Future of…

Making Materials Science and Engineering Data More Valuable Research Products (Postprint)

DTIC Science & Technology

2014-09-12

uncertainties in the publishing market - place.b Also, there is a possibility that some for-profit publishers could try to restrict access to digital...Kaufman JG, Glatzman JS (eds) Computerization and networking of materials databases: Second Volume, ASTM STP 1106. American Society for Testing and

Corner Office: Google's Dan Clancy

ERIC Educational Resources Information Center

Albanese, Andrew Richard; Oder, Norman

2009-01-01

This article presents an interview with Dan Clancy, engineering director for Google Book Search. In this interview, Clancy talks about the pending Google Book Search settlement, involving millions of volumes digitized from libraries, which drew a lawsuit from the Association of American Publishers and the Authors Guild. He also discusses pricing,…

Relation between digital peripheral arterial tonometry and brachial artery ultrasound measures of vascular function in patients with coronary artery disease and in healthy volunteers.

PubMed

Lee, Craig R; Bass, Almasa; Ellis, Kyle; Tran, Bryant; Steele, Savanna; Caughey, Melissa; Stouffer, George A; Hinderliter, Alan L

2012-03-01

Digital peripheral arterial tonometry (PAT) is an emerging, noninvasive method to assess vascular function. The physiology underlying this phenotype, however, remains unclear. Therefore, we evaluated the relation between digital PAT and established brachial artery ultrasound measures of vascular function under basal conditions and after reactive hyperemia. Using a cross-sectional study design, digital PAT and brachial artery ultrasonography with pulsed wave Doppler were simultaneously completed at baseline and after reactive hyperemia in both those with established coronary artery disease (n = 99) and healthy volunteers with low cardiovascular disease risk (n = 40). Under basal conditions, the digital pulse volume amplitude demonstrated a significant positive correlation with the brachial artery velocity-time integral that was independent of the arterial diameter, in both the healthy volunteer (r(s) = 0.64, p <0.001) and coronary artery disease (r(s) = 0.63, p <0.001) cohorts. Similar positive relations were observed with the baseline brachial artery blood flow velocity and blood flow. In contrast, no relation between the reactive hyperemia-evoked digital PAT ratio and either brachial artery flow-mediated dilation or shear stress was observed in either cohort (p = NS). In conclusion, these findings demonstrate that the digital PAT measures of vascular function more closely reflect basal blood flow in the brachial artery than reactive hyperemia-induced changes in the arterial diameter or flow velocity, and the presence of vascular disease does not modify the physiology underlying the digital PAT phenotype. Copyright © 2012 Elsevier Inc. All rights reserved.

1-Million droplet array with wide-field fluorescence imaging for digital PCR.

PubMed

Hatch, Andrew C; Fisher, Jeffrey S; Tovar, Armando R; Hsieh, Albert T; Lin, Robert; Pentoney, Stephen L; Yang, David L; Lee, Abraham P

2011-11-21

Digital droplet reactors are useful as chemical and biological containers to discretize reagents into picolitre or nanolitre volumes for analysis of single cells, organisms, or molecules. However, most DNA based assays require processing of samples on the order of tens of microlitres and contain as few as one to as many as millions of fragments to be detected. Presented in this work is a droplet microfluidic platform and fluorescence imaging setup designed to better meet the needs of the high-throughput and high-dynamic-range by integrating multiple high-throughput droplet processing schemes on the chip. The design is capable of generating over 1-million, monodisperse, 50 picolitre droplets in 2-7 minutes that then self-assemble into high density 3-dimensional sphere packing configurations in a large viewing chamber for visualization and analysis. This device then undergoes on-chip polymerase chain reaction (PCR) amplification and fluorescence detection to digitally quantify the sample's nucleic acid contents. Wide-field fluorescence images are captured using a low cost 21-megapixel digital camera and macro-lens with an 8-12 cm(2) field-of-view at 1× to 0.85× magnification, respectively. We demonstrate both end-point and real-time imaging ability to perform on-chip quantitative digital PCR analysis of the entire droplet array. Compared to previous work, this highly integrated design yields a 100-fold increase in the number of on-chip digitized reactors with simultaneous fluorescence imaging for digital PCR based assays.

A digital rat atlas of sectional anatomy

NASA Astrophysics Data System (ADS)

Yu, Li; Liu, Qian; Bai, Xueling; Liao, Yinping; Luo, Qingming; Gong, Hui

2006-09-01

This paper describes a digital rat alias of sectional anatomy made by milling. Two healthy Sprague-Dawley (SD) rat weighing 160-180 g were used for the generation of this atlas. The rats were depilated completely, then euthanized by Co II. One was via vascular perfusion, the other was directly frozen at -85 °C over 24 hour. After that, the frozen specimens were transferred into iron molds for embedding. A 3% gelatin solution colored blue was used to fill the molds and then frozen at -85 °C for one or two days. The frozen specimen-blocks were subsequently sectioned on the cryosection-milling machine in a plane oriented approximately transverse to the long axis of the body. The surface of specimen-blocks were imaged by a scanner and digitalized into 4,600 x2,580 x 24 bit array through a computer. Finally 9,475 sectional images (arterial vessel were not perfused) and 1,646 sectional images (arterial vessel were perfused) were captured, which made the volume of the digital atlas up to 369.35 Gbyte. This digital rat atlas is aimed at the whole rat and the rat arterial vessels are also presented. We have reconstructed this atlas. The information from the two-dimensional (2-D) images of serial sections and three-dimensional (3-D) surface model all shows that the digital rat atlas we constructed is high quality. This work lays the foundation for a deeper study of digital rat.

Digital diffractive optics: Have diffractive optics entered mainstream industry yet?

NASA Astrophysics Data System (ADS)

Kress, Bernard; Hejmadi, Vic

2010-05-01

When a new technology is integrated into industry commodity products and consumer electronic devices, and sold worldwide in retail stores, it is usually understood that this technology has then entered the realm of mainstream technology and therefore mainstream industry. Such a leap however does not come cheap, as it has a double edge sword effect: first it becomes democratized and thus massively developed by numerous companies for various applications, but also it becomes a commodity, and thus gets under tremendous pressure to cut down its production and integration costs while not sacrificing to performance. We will show, based on numerous examples extracted from recent industry history, that the field of Diffractive Optics is about to undergo such a major transformation. Such a move has many impacts on all facets of digital diffractive optics technology, from the optical design houses to the micro-optics foundries (for both mastering and volume replication), to the final product integrators or contract manufacturers. The main causes of such a transformation are, as they have been for many other technologies in industry, successive technological bubbles which have carried and lifted up diffractive optics technology within the last decades. These various technological bubbles have been triggered either by real industry needs or by virtual investment hype. Both of these causes will be discussed in the paper. The adjective ""digital"" in "digital diffractive optics" does not refer only, as it is done in digital electronics, to the digital functionality of the element (digital signal processing), but rather to the digital way they are designed (by a digital computer) and fabricated (as wafer level optics using digital masking techniques). However, we can still trace a very strong similarity between the emergence of micro-electronics from analog electronics half a century ago, and the emergence of digital optics from conventional optics today.

An application specific integrated circuit based multi-anode microchannel array readout system

NASA Technical Reports Server (NTRS)

Smeins, Larry G.; Stechman, John M.; Cole, Edward H.

1991-01-01

Size reduction of two new multi-anode microchannel array (MAMA) readout systems is described. The systems are based on two analog and one digital application specific integrated circuits (ASICs). The new readout systems reduce volume over previous discrete designs by 80 percent while improving electrical performance on virtually every significant parameter. Emphasis is made on the packaging used to achieve the volume reduction. Surface mount technology (SMT) is combined with modular construction for the analog portion of the readout. SMT reliability concerns and the board area impact of MIL SPEC SMT components is addressed. Package selection for the analog ASIC is discussed. Future sytems will require even denser packaging and the volume reduction progression is shown.

Method and apparatus for analyzing the internal chemistry and compositional variations of materials and devices

DOEpatents

Kazmerski, Lawrence L.

1989-01-01

A method and apparatus is disclosed for obtaining and mapping chemical compositional data for solid devices. It includes a SIMS mass analyzer or similar system capable of being rastered over a surface of the solid to sample the material at a pattern of selected points, as the surface is being eroded away by sputtering or a similar process. The data for each point sampled in a volume of the solid is digitally processed and indexed by element or molecule type, exact spacial location within the volume, and the concentration levels of the detected element or molecule types. This data can then be recalled and displayed for any desired planar view in the volume.

Method and apparatus for analyzing the internal chemistry and compositional variations of materials and devices

DOEpatents

Kazmerski, L.L.

1985-04-30

A method and apparatus is disclosed for obtaining and mapping chemical compositional data for solid devices. It includes a SIMS mass analyzer or similar system capable of being rastered over a surface of the solid to sample the material at a pattern of selected points, as the surface is being eroded away by sputtering or a similar process. The data for each point sampled in a volume of the solid is digitally processed and indexed by element or molecule type, exact spacial location within the volume, and the concentration levels of the detected element or molecule types. This data can then be recalled and displayed for any desired planar view in the volume.

Three-dimensional microscopic tomographic imagings of the cataract in a human lens in vivo

NASA Astrophysics Data System (ADS)

Masters, Barry R.

1998-10-01

The problem of three-dimensional visualization of a human lens in vivo has been solved by a technique of volume rendering a transformed series of 60 rotated Scheimpflug (a dual slit reflected light microscope) digital images. The data set was obtained by rotating the Scheimpflug camera about the optic axis of the lens in 3 degree increments. The transformed set of optical sections were first aligned to correct for small eye movements, and then rendered into a volume reconstruction with volume rendering computer graphics techniques. To help visualize the distribution of lens opacities (cataracts) in the living, human lens the intensity of light scattering was pseudocolor coded and the cataract opacities were displayed as a movie.

Numerical analysis of stiffened shells of revolution. Volume 2: Users' manual for STAR-02S - shell theory automated for rotational structures - 2 (statics), digital computer program

NASA Technical Reports Server (NTRS)

Svalbonas, V.

1973-01-01

A procedure for the structural analysis of stiffened shells of revolution is presented. A digital computer program based on the Love-Reissner first order shell theory was developed. The computer program can analyze orthotropic thin shells of revolution, subjected to unsymmetric distributed loading or concentrated line loads, as well as thermal strains. The geometrical shapes of the shells which may be analyzed are described. The shell wall cross section can be a sheet, sandwich, or reinforced sheet or sandwich. General stiffness input options are also available.

Optical and digital pattern recognition; Proceedings of the Meeting, Los Angeles, CA, Jan. 13-15, 1987

NASA Technical Reports Server (NTRS)

Liu, Hua-Kuang (Editor); Schenker, Paul (Editor)

1987-01-01

The papers presented in this volume provide an overview of current research in both optical and digital pattern recognition, with a theme of identifying overlapping research problems and methodologies. Topics discussed include image analysis and low-level vision, optical system design, object analysis and recognition, real-time hybrid architectures and algorithms, high-level image understanding, and optical matched filter design. Papers are presented on synthetic estimation filters for a control system; white-light correlator character recognition; optical AI architectures for intelligent sensors; interpreting aerial photographs by segmentation and search; and optical information processing using a new photopolymer.

Numerical nonlinear inelastic analysis of stiffened shells of revolution. Volume 3: Engineer's program manual for STARS-2P digital computer program

NASA Technical Reports Server (NTRS)

Svalbonas, V.; Levine, H.; Ogilvie, P.

1975-01-01

Engineering programming information is presented for the STARS-2P (shell theory automated for rotational structures-2P (plasticity)) digital computer program, and FORTRAN 4 was used in writing the various subroutines. The execution of this program requires the use of thirteen temporary storage units. The program was initially written and debugged on the IBM 370-165 computer and converted to the UNIVAC 1108 computer, where it utilizes approximately 60,000 words of core. Only basic FORTRAN library routines are required by the program: sine, cosine, absolute value, and square root.

Digital Fresnel reflection holography for high-resolution 3D near-wall flow measurement.

PubMed

Kumar, S Santosh; Hong, Jiarong

2018-05-14

We propose a novel backscatter holographic imaging system, as a compact and effective tool for 3D near-wall flow diagnostics at high resolutions, utilizing light reflected at the solid-liquid interface as a reference beam. The technique is fully calibrated, and is demonstrated in a densely seeded channel to achieve a spatial resolution of near-wall flows equivalent to or exceeding prior digital inline holographic measurements using local tracer seeding technique. Additionally, we examined the effects of seeding concentration and laser coherence on the measurement resolution and sample volume resolved, demonstrating the potential to manipulate sample domain by tuning the laser coherence profile.

IQARIS : a tool for the intelligent querying, analysis, and retrieval from information systems.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hummel, J. R.; Silver, R. B.

Information glut is one of the primary characteristics of the electronic age. Managing such large volumes of information (e.g., keeping track of the types, where they are, their relationships, who controls them, etc.) can be done efficiently with an intelligent, user-oriented information management system. The purpose of this paper is to describe a concept for managing information resources based on an intelligent information technology system developed by the Argonne National Laboratory for managing digital libraries. The Argonne system, Intelligent Query (IQ), enables users to query digital libraries and view the holdings that match the query from different perspectives.

A Novel Pretreatment-Free Duplex Chamber Digital PCR Detection System for the Absolute Quantitation of GMO Samples.

PubMed

Zhu, Pengyu; Wang, Chenguang; Huang, Kunlun; Luo, Yunbo; Xu, Wentao

2016-03-18

Digital polymerase chain reaction (PCR) has developed rapidly since it was first reported in the 1990s. However, pretreatments are often required during preparation for digital PCR, which can increase operation error. The single-plex amplification of both the target and reference genes may cause uncertainties due to the different reaction volumes and the matrix effect. In the current study, a quantitative detection system based on the pretreatment-free duplex chamber digital PCR was developed. The dynamic range, limit of quantitation (LOQ), sensitivity and specificity were evaluated taking the GA21 event as the experimental object. Moreover, to determine the factors that may influence the stability of the duplex system, we evaluated whether the pretreatments, the primary and secondary structures of the probes and the SNP effect influence the detection. The results showed that the LOQ was 0.5% and the sensitivity was 0.1%. We also found that genome digestion and single nucleotide polymorphism (SNP) sites affect the detection results, whereas the unspecific hybridization within different probes had little side effect. This indicated that the detection system was suited for both chamber-based and droplet-based digital PCR. In conclusion, we have provided a simple and flexible way of achieving absolute quantitation for genetically modified organism (GMO) genome samples using commercial digital PCR detection systems.

A Novel Pretreatment-Free Duplex Chamber Digital PCR Detection System for the Absolute Quantitation of GMO Samples

PubMed Central

Zhu, Pengyu; Wang, Chenguang; Huang, Kunlun; Luo, Yunbo; Xu, Wentao

2016-01-01

Digital polymerase chain reaction (PCR) has developed rapidly since it was first reported in the 1990s. However, pretreatments are often required during preparation for digital PCR, which can increase operation error. The single-plex amplification of both the target and reference genes may cause uncertainties due to the different reaction volumes and the matrix effect. In the current study, a quantitative detection system based on the pretreatment-free duplex chamber digital PCR was developed. The dynamic range, limit of quantitation (LOQ), sensitivity and specificity were evaluated taking the GA21 event as the experimental object. Moreover, to determine the factors that may influence the stability of the duplex system, we evaluated whether the pretreatments, the primary and secondary structures of the probes and the SNP effect influence the detection. The results showed that the LOQ was 0.5% and the sensitivity was 0.1%. We also found that genome digestion and single nucleotide polymorphism (SNP) sites affect the detection results, whereas the unspecific hybridization within different probes had little side effect. This indicated that the detection system was suited for both chamber-based and droplet-based digital PCR. In conclusion, we have provided a simple and flexible way of achieving absolute quantitation for genetically modified organism (GMO) genome samples using commercial digital PCR detection systems. PMID:26999129

The instrument control unit of SPICA SAFARI: a macro-unit to host all the digital control functionalities of the spectrometer

NASA Astrophysics Data System (ADS)

Di Giorgio, Anna Maria; Biondi, David; Saggin, Bortolino; Shatalina, Irina; Viterbini, Maurizio; Giusi, Giovanni; Liu, Scige J.; Cerulli-Irelli, Paquale; Van Loon, Dennis; Cara, Christophe

2012-09-01

We present the preliminary design of the Instrument Control Unit (ICU) of the SpicA FAR infrared Instrument (SAFARI), an imaging Fourier Transform Spectrometer (FTS) designed to give continuous wavelength coverage in both photometric and spectroscopic modes from around 34 to 210 µm. Due to the stringent requirements in terms of mass and volume, the overall SAFARI warm electronics will be composed by only two main units: Detector Control Unit and ICU. ICU is therefore a macro-unit incorporating the four digital sub-units dedicated to the control of the overall instrument functionalities: the Cooler Control Unit, the Mechanism Control Unit, the Digital processing Unit and the Power Supply Unit. Both the mechanical solution adopted to host the four sub-units and the internal electrical architecture are presented as well as the adopted redundancy approach.

Digital data base of lakes on the North Slope, Alaska

USGS Publications Warehouse

Walker, Kim-Marie; York, James; Murphy, Dennis; Sloan, C.E.

1986-01-01

The National Mapping Division and Water Resources Division of the U.S. Geological Survey have produced a digital data base of approximately 23,330 lakes on the North Slope of Alaska. The inventoried region consists of the area north of the 69th parallel and is composed of sixteen 1° x 3° quadrangles. The data base includes (1) locations of lake centers in latitude and longitude, (2) a unique number for each lake within a quadrangle, and (3) acreage for water classes (deep, shallow or turbid, and ice) within each lake and lake total. The digital data base is an easily accessible storage and retrieval system that will allow for rapid identification of a particular lake or region of lakes and its characteristics. The data base is designed to accommodate field study data such as lake depth, water quality, volume of water, ice thickness, and other pertinent information.

Proposal for internet-based Digital Dental Chart for personal dental identification in forensics.

PubMed

Hanaoka, Yoichi; Ueno, Asao; Tsuzuki, Tamiyuki; Kajiwara, Masahiro; Minaguchi, Kiyoshi; Sato, Yoshinobu

2007-05-03

A dental chart is very useful as a standard source of evidence in the personal identification of bodies. However, the kind of dental chart available will often vary as a number of types of odontogram have been developed where the visual representation of dental conditions has relied on hand-drawn representation. We propose the Digital Dental Chart (DDC) as a new style of dental chart, especially for open investigations aimed at establishing the identity of unknown bodies. Each DDC is constructed using actual oral digital images and dental data, and is easy to upload onto an Internet website. The DDC is a more useful forensic resource than the standard types of dental chart in current use as it has several advantages, among which are its ability to carry a large volume of information and reproduce dental conditions clearly and in detail on a cost-effective basis.

GLOBECOM '89 - IEEE Global Telecommunications Conference and Exhibition, Dallas, TX, Nov. 27-30, 1989, Conference Record. Volumes 1, 2, & 3

NASA Astrophysics Data System (ADS)

The present conference discusses topics in multiwavelength network technology and its applications, advanced digital radio systems in their propagation environment, mobile radio communications, switching programmability, advancements in computer communications, integrated-network management and security, HDTV and image processing in communications, basic exchange communications radio advancements in digital switching, intelligent network evolution, speech coding for telecommunications, and multiple access communications. Also discussed are network designs for quality assurance, recent progress in coherent optical systems, digital radio applications, advanced communications technologies for mobile users, communication software for switching systems, AI and expert systems in network management, intelligent multiplexing nodes, video and image coding, network protocols and performance, system methods in quality and reliability, the design and simulation of lightwave systems, local radio networks, mobile satellite communications systems, fiber networks restoration, packet video networks, human interfaces for future networks, and lightwave networking.

Fundamental Concepts of Digital Image Processing

DOE R&D Accomplishments Database

Twogood, R. E.

1983-03-01

The field of a digital-image processing has experienced dramatic growth and increasingly widespread applicability in recent years. Fortunately, advances in computer technology have kept pace with the rapid growth in volume of image data in these and other applications. Digital image processing has become economical in many fields of research and in industrial and military applications. While each application has requirements unique from the others, all are concerned with faster, cheaper, more accurate, and more extensive computation. The trend is toward real-time and interactive operations, where the user of the system obtains preliminary results within a short enough time that the next decision can be made by the human processor without loss of concentration on the task at hand. An example of this is the obtaining of two-dimensional (2-D) computer-aided tomography (CAT) images. A medical decision might be made while the patient is still under observation rather than days later.

Rotationally Adaptive Flight Test Surface

NASA Technical Reports Server (NTRS)

Barrett, Ron

1999-01-01

Research on a new design of flutter exciter vane using adaptive materials was conducted. This novel design is based on all-moving aerodynamic surface technology and consists of a structurally stiff main spar, a series of piezoelectric actuator elements and an aerodynamic shell which is pivoted around the main spar. The work was built upon the current missile-type all-moving surface designs and change them so they are better suited for flutter excitation through the transonic flight regime. The first portion of research will be centered on aerodynamic and structural modeling of the system. USAF DatCom and vortex lattice codes was used to capture the fundamental aerodynamics of the vane. Finite element codes and laminated plate theory and virtual work analyses will be used to structurally model the aerodynamic vane and wing tip. Following the basic modeling, a flutter test vane was designed. Each component within the structure was designed to meet the design loads. After the design loads are met, then the deflections will be maximized and the internal structure will be laid out. In addition to the structure, a basic electrical control network will be designed which will be capable of driving a scaled exciter vane. The third and final stage of main investigation involved the fabrication of a 1/4 scale vane. This scaled vane was used to verify kinematics and structural mechanics theories on all-moving actuation. Following assembly, a series of bench tests was conducted to determine frequency response, electrical characteristics, mechanical and kinematic properties. Test results indicate peak-to-peak deflections of 1.1 deg with a corner frequency of just over 130 Hz.

Improvement of a Pneumatic Control Valve with Self-Holding Function

NASA Astrophysics Data System (ADS)

Dohta, Shujiro; Akagi, Tetsuya; Kobayashi, Wataru; Shimooka, So; Masago, Yusuke

2017-10-01

The purpose of this study is to develop a small-sized, lightweight and low-cost control valve with low energy consumption and to apply it to the assistive system. We have developed some control valves; a tiny on/off valve using a vibration motor, and an on/off valve with self-holding function. We have also proposed and tested the digital servo valve with self-holding function using permanent magnets and a small-sized servo motor. In this paper, in order to improve the valve, an analytical model of the digital servo valve is proposed. And the simulated results by using the analytical model and identified parameters were compared with the experimental results. Then, the improved digital servo valve was designed based on the calculated results and tested. As a result, we realized the digital servo valve that can control the flow rate more precisely while maintaining its volume and weight compared with the previous valve. As an application of the improved valve, a position control system of rubber artificial muscle was built and the position control was performed successfully.

Geographic information system (GIS)-based maps of Appalachian basin oil and gas fields: Chapter C.2 in Coal and petroleum resources in the Appalachian basin: distribution, geologic framework, and geochemical character

USGS Publications Warehouse

Ryder, Robert T.; Kinney, Scott A.; Suitt, Stephen E.; Merrill, Matthew D.; Trippi, Michael H.; Ruppert, Leslie F.; Ryder, Robert T.

2014-01-01

In 2006 and 2007, the greenline Appalachian basin field maps were digitized under the supervision of Scott Kinney and converted to geographic information system (GIS) files for chapter I.1 (this volume). By converting these oil and gas field maps to a digital format and maintaining the field names where noted, they are now available for a variety of oil and gas and possibly carbon-dioxide sequestration projects. Having historical names assigned to known digitized conventional fields provides a convenient classification scheme into which cumulative production and ultimate field-size databases can be organized. Moreover, as exploratory and development drilling expands across the basin, many previously named fields that were originally treated as conventional fields have evolved into large, commonly unnamed continuous-type accumulations. These new digital maps will facilitate a comparison between EUR values from recently drilled, unnamed parts of continuous accumulations and EUR values from named fields discovered early during the exploration cycle of continuous accumulations.

Digital Biomass Accumulation Using High-Throughput Plant Phenotype Data Analysis.

PubMed

Rahaman, Md Matiur; Ahsan, Md Asif; Gillani, Zeeshan; Chen, Ming

2017-09-01

Biomass is an important phenotypic trait in functional ecology and growth analysis. The typical methods for measuring biomass are destructive, and they require numerous individuals to be cultivated for repeated measurements. With the advent of image-based high-throughput plant phenotyping facilities, non-destructive biomass measuring methods have attempted to overcome this problem. Thus, the estimation of plant biomass of individual plants from their digital images is becoming more important. In this paper, we propose an approach to biomass estimation based on image derived phenotypic traits. Several image-based biomass studies state that the estimation of plant biomass is only a linear function of the projected plant area in images. However, we modeled the plant volume as a function of plant area, plant compactness, and plant age to generalize the linear biomass model. The obtained results confirm the proposed model and can explain most of the observed variance during image-derived biomass estimation. Moreover, a small difference was observed between actual and estimated digital biomass, which indicates that our proposed approach can be used to estimate digital biomass accurately.

A Pipeline for 3D Digital Optical Phenotyping Plant Root System Architecture

NASA Astrophysics Data System (ADS)

Davis, T. W.; Shaw, N. M.; Schneider, D. J.; Shaff, J. E.; Larson, B. G.; Craft, E. J.; Liu, Z.; Kochian, L. V.; Piñeros, M. A.

2017-12-01

This work presents a new pipeline for digital optical phenotyping the root system architecture of agricultural crops. The pipeline begins with a 3D root-system imaging apparatus for hydroponically grown crop lines of interest. The apparatus acts as a self-containing dark room, which includes an imaging tank, motorized rotating bearing and digital camera. The pipeline continues with the Plant Root Imaging and Data Acquisition (PRIDA) software, which is responsible for image capturing and storage. Once root images have been captured, image post-processing is performed using the Plant Root Imaging Analysis (PRIA) command-line tool, which extracts root pixels from color images. Following the pre-processing binarization of digital root images, 3D trait characterization is performed using the next-generation RootReader3D software. RootReader3D measures global root system architecture traits, such as total root system volume and length, total number of roots, and maximum rooting depth and width. While designed to work together, the four stages of the phenotyping pipeline are modular and stand-alone, which provides flexibility and adaptability for various research endeavors.

Cardiac chamber volumes by echocardiography using a new mathematical method: A promising technique for zero-G use

NASA Technical Reports Server (NTRS)

Buckey, J. C.; Beattie, J. M.; Gaffney, F. A.; Nixon, J. V.; Blomqvist, C. G.

1984-01-01

Accurate, reproducible, and non-invasive means for ventricular volume determination are needed for evaluating cardiovascular function zero-gravity. Current echocardiographic methods, particularly for the right ventricle, suffer from a large standard error. A new mathematical approach, recently described by Watanabe et al., was tested on 1 normal formalin-fixed human hearts suspended in a mineral oil bath. Volumes are estimated from multiple two-dimensional echocardiographic views recorded from a single point at sequential angles. The product of sectional cavity area and center of mass for each view summed over the range of angles (using a trapezoidal rule) gives volume. Multiple (8-14) short axis right ventricle and left ventricle views at 5.0 deg intervals were videotaped. The images were digitized by two independent observers (leading-edge to leading-edge technique) and analyzed using a graphics tablet and microcomputer. Actual volumes were determined by filling the chambers with water. These data were compared to the mean of the two echo measurements.

Accurate, consistent, and fast droplet splitting and dispensing in electrowetting on dielectric digital microfluidics

NASA Astrophysics Data System (ADS)

Nikapitiya, N. Y. Jagath B.; Nahar, Mun Mun; Moon, Hyejin

2017-12-01

This letter reports two novel electrode design considerations to satisfy two very important aspects of EWOD operation—(1) Highly consistent volume of generated droplets and (2) Highly improved accuracy in the generated droplet volume. Considering the design principles investigated two novel designs were proposed; L-junction electrode design to offer high throughput droplet generation and Y-junction electrode design to split a droplet very fast while maintaining equal volume of each part. Devices of novel designs were fabricated and tested, and the results are compared with those of conventional approach. It is demonstrated that inaccuracy and inconsistency of droplet volume dispensed in the device with novel electrode designs are as low as 0.17 and 0.10%, respectively, while those of conventional approach are 25 and 0.76%, respectively. The dispensing frequency is enhanced from 4 to 9 Hz by using the novel design.

A Mechanics-Based Framework Leading to Improved Diagnosis and Treatment of Hydrocephalus

NASA Astrophysics Data System (ADS)

Cohen, Benjamin; Soren, Vedels; Wagshul, Mark; Egnor, Michael; Voorhees, Abram; Wei, Timothy

2007-11-01

Hydrocephalus is defined as an accumulation of cerebrospinal fluid (CSF) in the cranium, at the expense of brain tissue. The result is a disruption of the normal pressure and/or flow dynamics of the intracranial blood and CSF. We seek to introduce integral control volume analysis to the study of hydrocephalus. The goal is to provide a first principles framework to integrate a broad spectrum of sometimes disparate investigations into a highly complex, multidisciplinary problem. The general technique for the implementation of control volumes to hydrocephalus will be presented. This includes factors faced in choosing control volumes and making the required measurements to evaluate mass and momentum conservation. In addition, the use of our Digital Particle Image Velocimetry (DPIV) processing program has been extended to measure the displacement of the ventricles' walls from Magnetic Resonance (MR) images. This is done to determine the volume change of the intracranial fluid spaces.

Harnessing the Power of Education Research Databases with the Pearl-Harvesting Methodological Framework for Information Retrieval

ERIC Educational Resources Information Center

Sandieson, Robert W.; Kirkpatrick, Lori C.; Sandieson, Rachel M.; Zimmerman, Walter

2010-01-01

Digital technologies enable the storage of vast amounts of information, accessible with remarkable ease. However, along with this facility comes the challenge to find pertinent information from the volumes of nonrelevant information. The present article describes the pearl-harvesting methodological framework for information retrieval. Pearl…

New Perspectives on Teaching and Working with Languages in the Digital Era

ERIC Educational Resources Information Center

Pareja-Lora, Antonio, Ed.; Calle-Martínez, Cristina, Ed.; Rodríguez-Arancón, Pilar, Ed.

2016-01-01

This volume offers a comprehensive, up-to-date, empirical and methodological view over the new scenarios and environments for language teaching and learning recently emerged (e.g. blended learning, e-learning, ubiquitous learning, social learning, autonomous learning or lifelong learning), and also over some of the new approaches to language…

Numerical nonlinear inelastic analysis of stiffened shells of revolution. Volume 4: Satellite-1P program for STARS-2P digital computer program

NASA Technical Reports Server (NTRS)

Svalbonas, V.; Ogilvie, P.

1975-01-01

A special data debugging package called SAT-1P created for the STARS-2P computer program is described. The program was written exclusively in FORTRAN 4 for the IBM 370-165 computer, and then converted to the UNIVAC 1108.

PRESTO Digital Computer Code User’s Guide. Volume I. System Overview. Revision A.

DTIC Science & Technology

1980-10-31

Two, Three, Five or Six should address a request to: Headquarters Defense Nuclear Agency Attention: RAEE Washington, D.C. 20305 Similarly, readers...Agency Harry Diamond Laboratories ATTN: RAAE Department of the Army ATTN: NATA ATTN: 21500 ATTN: RAEE ATTN: Chief Div 10000 4 cy ATTN: TITL ATTN

Curriculum Review. Volume 44, Number 8

ERIC Educational Resources Information Center

Curriculum Review, 2005

2005-01-01

Each month, "Curriculum Review" offers teachers mutual support, the sharing of ideas, and words of encouragement to help them face challenges in the classroom. The April 2005 issue of "Curriculum Review" contains the following articles: (1) "We Hear from Readers"; (2) "What They're Saying"; (3) "Google Plans to Digitize Big Library Collections";…

30 CFR 550.297 - What information must a CID contain?

Code of Federal Regulations, 2014 CFR

2014-07-01

... drilled before your CID submittal that define the extent of the reservoirs. You must notify BOEM of any well that is drilled to total depth during the CID evaluation period and you may be required to update..., caliper curves) curves in an acceptable digital format; (4) Sidewall core/whole core and pressure-volume...

30 CFR 550.297 - What information must a CID contain?

Code of Federal Regulations, 2013 CFR

2013-07-01

... drilled before your CID submittal that define the extent of the reservoirs. You must notify BOEM of any well that is drilled to total depth during the CID evaluation period and you may be required to update..., caliper curves) curves in an acceptable digital format; (4) Sidewall core/whole core and pressure-volume...

30 CFR 550.297 - What information must a CID contain?

Code of Federal Regulations, 2012 CFR

2012-07-01

... drilled before your CID submittal that define the extent of the reservoirs. You must notify BOEM of any well that is drilled to total depth during the CID evaluation period and you may be required to update..., caliper curves) curves in an acceptable digital format; (4) Sidewall core/whole core and pressure-volume...

Medical Surveillance Monthly Report. Volume 19, Number 5

DTIC Science & Technology

2012-05-01

genital herpes ” (ICD-9-CM 054.1 with any fi ft h digit) in any diagnostic position. Incidence rates of MHD were com- pared between three groups of active...cervi- cal cancers and 80 percent of genital warts, was licensed in the United States.2 Consis- tent with the Centers for Disease Control and

Night Attack Workload Steering Group. Volume 3. Simulation and Human Factors Subgroup

DTIC Science & Technology

1982-06-01

information intepretation . The second is the use of pictorial formats or computer generated displays that combine many present-day displays into a small number...base exists in any form (digital, film , or model) which supports the wide area, long track, low level requirements levied by night attack training

Images in Language: Metaphors and Metamorphoses. Visual Learning. Volume 1

ERIC Educational Resources Information Center

Benedek, Andras, Ed.; Nyiri, Kristof, Ed.

2011-01-01

Learning and teaching are faced with radically new challenges in today's rapidly changing world and its deeply transformed communicational environment. We are living in an era of images. Contemporary visual technology--film, video, interactive digital media--is promoting but also demanding a new approach to education: the age of visual learning…

Corpus Callosum Morphometrics in Young Children with Autism Spectrum Disorder

ERIC Educational Resources Information Center

Boger-Megiddo, Inbal; Shaw, Dennis W. W.; Friedman, Seth D.; Sparks, Bobbi F.; Artru, Alan A.; Giedd, Jay N.; Dawson, Geraldine; Dager, Stephen R.

2006-01-01

This study assessed digital corpus callosum cross sectional areas in 3-4 year olds with autism spectrum disorder (ASD) compared to typically developing (TD) and developmentally delayed (DD) children. Though not different in absolute size compared to TD, ASD callosums were disproportionately small adjusted for increased ASD cerebral volume. ASD…

Chronicle of Higher Education. Volume 51, Number 27, March 11, 2005

ERIC Educational Resources Information Center

Chronicle of Higher Education, 2005

2005-01-01

"Chronicle of Higher Education" presents an abundant source of news and information for college and university faculty members and administrators. This March 11, 2005 issue of "Chronicle of Higher Education" includes the following articles: (1) "Don't Get Goggle-Eyed Over Google's Plan to Digitize" (Herring, Mark Y.);…

Micro-computed tomography of pupal metamorphosis in the solitary bee Megachile rotundata

USDA-ARS?s Scientific Manuscript database

Insect metamorphosis involves a complex change in form and function, but most of these changes are internal and treated as a black box. In this study, we examined development of the solitary bee, Megachile rotundata, using micro-computed tomography (µCT) and digital volume analysis. We describe deve...

A novel method for electronic measurement and recording of surgical drain output.

PubMed

van Duren, Bernard Hendrik; van Boxel, Gijsbert Isaac

2017-04-01

Surgical drains are used to collect and measure fluids (e.g. serous fluid, lymph, blood, etc.). The volume of fluid in the container is measured using graded markings on the container and then recorded manually on a "drain chart" allowing for manual rate calculations. This method is dependant on regularly checking the volume of the drain and recording the value accurately; unfortunately, this is often not feasible due to staffing levels and time constraints. This results in inaccurate "drain charts" making clinical decisions based on these figures unreliable. Often the lack of confidence in these measurements leads to delayed drain removal with consequent increased infection risks and potential delayed discharge. Accurate digital measurement of drain content would have a significant impact on clinical care. This paper describes a digital technology to measure volume, making use of a positive terminal at the lowest point of the vessel and negative (sensor) terminals placed at accurate intervals along an axis of the vessel. A proof-of-concept prototype was developed using commercially available electronic components to test the feasibility of a technology for electronic measurement and recording of surgical drain content. In a simulated environment, the proposed technology was shown to be effective and accurate. The proposed electronic drain has a number of advantages over currently used devices in saving time and easing pressure on nursing staff, reduce disturbance of patients, and allows for preset alarms.

Towards large-scale mapping of urban three-dimensional structure using Landsat imagery and global elevation datasets

NASA Astrophysics Data System (ADS)

Wang, P.; Huang, C.

2017-12-01

The three-dimensional (3D) structure of buildings and infrastructures is fundamental to understanding and modelling of the impacts and challenges of urbanization in terms of energy use, carbon emissions, and earthquake vulnerabilities. However, spatially detailed maps of urban 3D structure have been scarce, particularly in fast-changing developing countries. We present here a novel methodology to map the volume of buildings and infrastructures at 30 meter resolution using a synergy of Landsat imagery and openly available global digital surface models (DSMs), including the Shuttle Radar Topography Mission (SRTM), ASTER Global Digital Elevation Map (GDEM), ALOS World 3D - 30m (AW3D30), and the recently released global DSM from the TanDEM-X mission. Our method builds on the concept of object-based height profile to extract height metrics from the DSMs and use a machine learning algorithm to predict height and volume from the height metrics. We have tested this algorithm in the entire England and assessed our result using Lidar measurements in 25 England cities. Our initial assessments achieved a RMSE of 1.4 m (R2 = 0.72) for building height and a RMSE of 1208.7 m3 (R2 = 0.69) for building volume, demonstrating the potential of large-scale applications and fully automated mapping of urban structure.

X-ray microtomography analysis of soil structure deformation caused by centrifugation

NASA Astrophysics Data System (ADS)

Schlüter, Steffen; Leuther, Frederic; Vogler, Steffen; Vogel, Hans-Jörg

2016-04-01

Centrifugation provides a fast method to measure soil water retention curves over a wide moisture range. However, deformation of soil structure may occur at high angular velocities in the centrifuge. The objective of this study was to capture these changes in soil structure with X-ray microtomography and to measure local deformations via digital volume correlation. Two samples were investigated that differ in texture and rock content. A detailed analysis of the pore space reveals an interplay between shrinkage due to drying and soil compaction due to compression. Macroporosity increases at moderate angular velocity because of crack formation due to moisture release. At higher angular velocities, corresponding to capillary pressure of <-100kPa, macroporosity decreases again because of structure deformation due to compression. While volume changes due to swelling clay minerals are immanent to any drying process, the compaction of soil is a specific drawback of the centrifugation method. A new protocol for digital volume correlation was developed to analyze the spatial heterogeneity of deformation. In both samples the displacement of soil constituents is highest in the top part of the sample and exhibits high lateral variability explained by the spatial distribution of macropores in the sample. Centrifugation should therefore only be applied after the completion of all other hydraulic or thermal experiments, or any other analysis that depends on the integrity of soil structure.

X-ray microtomography analysis of soil structure deformation caused by centrifugation

NASA Astrophysics Data System (ADS)

Schlüter, S.; Leuther, F.; Vogler, S.; Vogel, H.-J.

2016-01-01

Centrifugation provides a fast method to measure soil water retention curves over a wide moisture range. However, deformation of soil structure may occur at high angular velocities in the centrifuge. The objective of this study was to capture these changes in soil structure with X-ray microtomography and to measure local deformations via digital volume correlation. Two samples were investigated that differ in texture and rock content. A detailed analysis of the pore space reveals an interplay between shrinkage due to drying and soil compaction due to compression. Macroporosity increases at moderate angular velocity because of crack formation due to moisture release. At higher angular velocities, corresponding to capillary pressure of ψ < -100 kPa, macroporosity decreases again because of structure deformation due to compression. While volume changes due to swelling clay minerals are immanent in any drying process, the compaction of soil is a specific drawback of the centrifugation method. A new protocol for digital volume correlation was developed to analyze the spatial heterogeneity of deformation. In both samples the displacement of soil constituents is highest in the top part of the sample and exhibits high lateral variability explained by the spatial distribution of macropores in the sample. Centrifugation should therefore only be applied after the completion of all other hydraulic or thermal experiments, or any other analysis that depends on the integrity of soil structure.

Self-digitization chip for single-cell genotyping of cancer-related mutations

PubMed Central

Monroe, Luke D.; Kreutz, Jason E.; Schneider, Thomas; Fujimoto, Bryant S.; Chiu, Daniel T.; Radich, Jerald P.; Paguirigan, Amy L.

2018-01-01

Cancer is a heterogeneous disease, and patient-level genetic assessments can guide therapy choice and impact prognosis. However, little is known about the impact of genetic variability within a tumor, intratumoral heterogeneity (ITH), on disease progression or outcome. Current approaches using bulk tumor specimens can suggest the presence of ITH, but only single-cell genetic methods have the resolution to describe the underlying clonal structures themselves. Current techniques tend to be labor and resource intensive and challenging to characterize with respect to sources of biological and technical variability. We have developed a platform using a microfluidic self-digitization chip to partition cells in stationary volumes for cell imaging and allele-specific PCR. Genotyping data from only confirmed single-cell volumes is obtained and subject to a variety of relevant quality control assessments such as allele dropout, false positive, and false negative rates. We demonstrate single-cell genotyping of the NPM1 type A mutation, an important prognostic indicator in acute myeloid leukemia, on single cells of the cell line OCI-AML3, describing a more complex zygosity distribution than would be predicted via bulk analysis. PMID:29718986

Denoised ordered subset statistically penalized algebraic reconstruction technique (DOS-SPART) in digital breast tomosynthesis

NASA Astrophysics Data System (ADS)

Garrett, John; Li, Yinsheng; Li, Ke; Chen, Guang-Hong

2017-03-01

Digital breast tomosynthesis (DBT) is a three dimensional (3D) breast imaging modality in which projections are acquired over a limited angular span around the compressed breast and reconstructed into image slices parallel to the detector. DBT has been shown to help alleviate the breast tissue overlapping issues of two dimensional (2D) mammography. Since the overlapping tissues may simulate cancer masses or obscure true cancers, this improvement is critically important for improved breast cancer screening and diagnosis. In this work, a model-based image reconstruction method is presented to show that spatial resolution in DBT volumes can be maintained while dose is reduced using the presented method when compared to that of a state-of-the-art commercial reconstruction technique. Spatial resolution was measured in phantom images and subjectively in a clinical dataset. Noise characteristics were explored in a cadaver study. In both the quantitative and subjective results the image sharpness was maintained and overall image quality was maintained at reduced doses when the model-based iterative reconstruction was used to reconstruct the volumes.

Accurate B-spline-based 3-D interpolation scheme for digital volume correlation

NASA Astrophysics Data System (ADS)

Ren, Maodong; Liang, Jin; Wei, Bin

2016-12-01

An accurate and efficient 3-D interpolation scheme, based on sampling theorem and Fourier transform technique, is proposed to reduce the sub-voxel matching error caused by intensity interpolation bias in digital volume correlation. First, the influence factors of the interpolation bias are investigated theoretically using the transfer function of an interpolation filter (henceforth filter) in the Fourier domain. A law that the positional error of a filter can be expressed as a function of fractional position and wave number is found. Then, considering the above factors, an optimized B-spline-based recursive filter, combining B-spline transforms and least squares optimization method, is designed to virtually eliminate the interpolation bias in the process of sub-voxel matching. Besides, given each volumetric image containing different wave number ranges, a Gaussian weighting function is constructed to emphasize or suppress certain of wave number ranges based on the Fourier spectrum analysis. Finally, a novel software is developed and series of validation experiments were carried out to verify the proposed scheme. Experimental results show that the proposed scheme can reduce the interpolation bias to an acceptable level.

ELUCID - Exploring the Local Universe with ReConstructed Initial Density Field III: Constrained Simulation in the SDSS Volume

NASA Astrophysics Data System (ADS)

Wang, Huiyuan; Mo, H. J.; Yang, Xiaohu; Zhang, Youcai; Shi, JingJing; Jing, Y. P.; Liu, Chengze; Li, Shijie; Kang, Xi; Gao, Yang

2016-11-01

A method we developed recently for the reconstruction of the initial density field in the nearby universe is applied to the Sloan Digital Sky Survey Data Release 7. A high-resolution N-body constrained simulation (CS) of the reconstructed initial conditions, with 30723 particles evolved in a 500 {h}-1 {Mpc} box, is carried out and analyzed in terms of the statistical properties of the final density field and its relation with the distribution of Sloan Digital Sky Survey galaxies. We find that the statistical properties of the cosmic web and the halo populations are accurately reproduced in the CS. The galaxy density field is strongly correlated with the CS density field, with a bias that depends on both galaxy luminosity and color. Our further investigations show that the CS provides robust quantities describing the environments within which the observed galaxies and galaxy systems reside. Cosmic variance is greatly reduced in the CS so that the statistical uncertainties can be controlled effectively, even for samples of small volumes.

Self-digitization chip for single-cell genotyping of cancer-related mutations.

PubMed

Thompson, Alison M; Smith, Jordan L; Monroe, Luke D; Kreutz, Jason E; Schneider, Thomas; Fujimoto, Bryant S; Chiu, Daniel T; Radich, Jerald P; Paguirigan, Amy L

2018-01-01

Cancer is a heterogeneous disease, and patient-level genetic assessments can guide therapy choice and impact prognosis. However, little is known about the impact of genetic variability within a tumor, intratumoral heterogeneity (ITH), on disease progression or outcome. Current approaches using bulk tumor specimens can suggest the presence of ITH, but only single-cell genetic methods have the resolution to describe the underlying clonal structures themselves. Current techniques tend to be labor and resource intensive and challenging to characterize with respect to sources of biological and technical variability. We have developed a platform using a microfluidic self-digitization chip to partition cells in stationary volumes for cell imaging and allele-specific PCR. Genotyping data from only confirmed single-cell volumes is obtained and subject to a variety of relevant quality control assessments such as allele dropout, false positive, and false negative rates. We demonstrate single-cell genotyping of the NPM1 type A mutation, an important prognostic indicator in acute myeloid leukemia, on single cells of the cell line OCI-AML3, describing a more complex zygosity distribution than would be predicted via bulk analysis.

Color and Vector Flow Imaging in Parallel Ultrasound With Sub-Nyquist Sampling.

PubMed

Madiena, Craig; Faurie, Julia; Poree, Jonathan; Garcia, Damien; Garcia, Damien; Madiena, Craig; Faurie, Julia; Poree, Jonathan

2018-05-01

RF acquisition with a high-performance multichannel ultrasound system generates massive data sets in short periods of time, especially in "ultrafast" ultrasound when digital receive beamforming is required. Sampling at a rate four times the carrier frequency is the standard procedure since this rule complies with the Nyquist-Shannon sampling theorem and simplifies quadrature sampling. Bandpass sampling (or undersampling) outputs a bandpass signal at a rate lower than the maximal frequency without harmful aliasing. Advantages over Nyquist sampling are reduced storage volumes and data workflow, and simplified digital signal processing tasks. We used RF undersampling in color flow imaging (CFI) and vector flow imaging (VFI) to decrease data volume significantly (factor of 3 to 13 in our configurations). CFI and VFI with Nyquist and sub-Nyquist samplings were compared in vitro and in vivo. The estimate errors due to undersampling were small or marginal, which illustrates that Doppler and vector Doppler images can be correctly computed with a drastically reduced amount of RF samples. Undersampling can be a method of choice in CFI and VFI to avoid information overload and reduce data transfer and storage.

Dependence of the clustering properties of galaxies on stellar velocity dispersion in the Main galaxy sample of SDSS DR10

NASA Astrophysics Data System (ADS)

Deng, Xin-Fa; Song, Jun; Chen, Yi-Qing; Jiang, Peng; Ding, Ying-Ping

2014-08-01

Using two volume-limited Main galaxy samples of the Sloan Digital Sky Survey Data Release 10 (SDSS DR10), we investigate the dependence of the clustering properties of galaxies on stellar velocity dispersion by cluster analysis. It is found that in the luminous volume-limited Main galaxy sample, except at r=1.2, richer and larger systems can be more easily formed in the large stellar velocity dispersion subsample, while in the faint volume-limited Main galaxy sample, at r≥0.9, an opposite trend is observed. According to statistical analyses of the multiplicity functions, we conclude in two volume-limited Main galaxy samples: small stellar velocity dispersion galaxies preferentially form isolated galaxies, close pairs and small group, while large stellar velocity dispersion galaxies preferentially inhabit the dense groups and clusters. However, we note the difference between two volume-limited Main galaxy samples: in the faint volume-limited Main galaxy sample, at r≥0.9, the small stellar velocity dispersion subsample has a higher proportion of galaxies in superclusters ( n≥200) than the large stellar velocity dispersion subsample.

Volume error analysis for lung nodules attached to pulmonary vessels in an anthropomorphic thoracic phantom

NASA Astrophysics Data System (ADS)

Kinnard, Lisa M.; Gavrielides, Marios A.; Myers, Kyle J.; Zeng, Rongping; Peregoy, Jennifer; Pritchard, William; Karanian, John W.; Petrick, Nicholas

2008-03-01

High-resolution CT, three-dimensional (3D) methods for nodule volumetry have been introduced, with the hope that such methods will be more accurate and consistent than currently used planar measures of size. However, the error associated with volume estimation methods still needs to be quantified. Volume estimation error is multi-faceted in the sense that it is impacted by characteristics of the patient, the software tool and the CT system. The overall goal of this research is to quantify the various sources of measurement error and, when possible, minimize their effects. In the current study, we estimated nodule volume from ten repeat scans of an anthropomorphic phantom containing two synthetic spherical lung nodules (diameters: 5 and 10 mm; density: -630 HU), using a 16-slice Philips CT with 20, 50, 100 and 200 mAs exposures and 0.8 and 3.0 mm slice thicknesses. True volume was estimated from an average of diameter measurements, made using digital calipers. We report variance and bias results for volume measurements as a function of slice thickness, nodule diameter, and X-ray exposure.

Semiautomatic regional segmentation to measure orbital fat volumes in thyroid-associated ophthalmopathy. A validation study.

PubMed

Comerci, M; Elefante, A; Strianese, D; Senese, R; Bonavolontà, P; Alfano, B; Bonavolontà, B; Brunetti, A

2013-08-01

This study was designed to validate a novel semi-automated segmentation method to measure regional intra-orbital fat tissue volume in Graves' ophthalmopathy. Twenty-four orbits from 12 patients with Graves' ophthalmopathy, 24 orbits from 12 controls, ten orbits from five MRI study simulations and two orbits from a digital model were used. Following manual region of interest definition of the orbital volumes performed by two operators with different levels of expertise, an automated procedure calculated intra-orbital fat tissue volumes (global and regional, with automated definition of four quadrants). In patients with Graves' disease, clinical activity score and degree of exophthalmos were measured and correlated with intra-orbital fat volumes. Operator performance was evaluated and statistical analysis of the measurements was performed. Accurate intra-orbital fat volume measurements were obtained with coefficients of variation below 5%. The mean operator difference in total fat volume measurements was 0.56%. Patients had significantly higher intra-orbital fat volumes than controls (p<0.001 using Student's t test). Fat volumes and clinical score were significantly correlated (p<0.001). The semi-automated method described here can provide accurate, reproducible intra-orbital fat measurements with low inter-operator variation and good correlation with clinical data.

Clear-cornea cataract surgery: pupil size and shape changes, along with anterior chamber volume and depth changes. A Scheimpflug imaging study.

PubMed

Kanellopoulos, Anastasios John; Asimellis, George

2014-01-01

To investigate, by high-precision digital analysis of data provided by Scheimpflug imaging, changes in pupil size and shape and anterior chamber (AC) parameters following cataract surgery. The study group (86 eyes, patient age 70.58±10.33 years) was subjected to cataract removal surgery with in-the-bag intraocular lens implantation (pseudophakic). A control group of 75 healthy eyes (patient age 51.14±16.27 years) was employed for comparison. Scheimpflug imaging (preoperatively and 3 months postoperatively) was employed to investigate central corneal thickness, AC depth, and AC volume. In addition, by digitally analyzing the black-and-white dotted line pupil edge marking in the Scheimpflug "large maps," the horizontal and vertical pupil diameters were individually measured and the pupil eccentricity was calculated. The correlations between AC depth and pupil shape parameters versus patient age, as well as the postoperative AC and pupil size and shape changes, were investigated. Compared to preoperative measurements, AC depth and AC volume of the pseudophakic eyes increased by 0.99±0.46 mm (39%; P<0.001) and 43.57±24.59 mm(3) (36%; P<0.001), respectively. Pupil size analysis showed that the horizontal pupil diameter was reduced by -0.27±0.22 mm (-9.7%; P=0.001) and the vertical pupil diameter was reduced by -0.32±0.24 mm (-11%; P<0.001). Pupil eccentricity was reduced by -39.56%; P<0.001. Cataract extraction surgery appears to affect pupil size and shape, possibly in correlation to AC depth increase. This novel investigation based on digital analysis of Scheimpflug imaging data suggests that the cataract postoperative photopic pupil is reduced and more circular. These changes appear to be more significant with increasing patient age.

Health care using high-bandwidth communication to overcome distance and time barriers for the Department of Defense

NASA Astrophysics Data System (ADS)

Mun, Seong K.; Freedman, Matthew T.; Gelish, Anthony; de Treville, Robert E.; Sheehy, Monet R.; Hansen, Mark; Hill, Mac; Zacharia, Elisabeth; Sullivan, Michael J.; Sebera, C. Wayne

1993-01-01

Image management and communications (IMAC) network, also known as picture archiving and communication system (PACS) consists of (1) digital image acquisition, (2) image review station (3) image storage device(s), image reading workstation, and (4) communication capability. When these subsystems are integrated over a high speed communication technology, possibilities are numerous in improving the timeliness and quality of diagnostic services within a hospital or at remote clinical sites. Teleradiology system uses basically the same hardware configuration together with a long distance communication capability. Functional characteristics of components are highlighted. Many medical imaging systems are already in digital form. These digital images constitute approximately 30% of the total volume of images produced in a radiology department. The remaining 70% of images include conventional x-ray films of the chest, skeleton, abdomen, and GI tract. Unless one develops a method of handling these conventional film images, global improvement in productivity in image management and radiology service throughout a hospital cannot be achieved. Currently, there are two method of producing digital information representing these conventional analog images for IMAC: film digitizers that scan the conventional films, and computed radiography (CR) that captures x-ray images using storage phosphor plate that is subsequently scanned by a laser beam.

Streamlining Metadata and Data Management for Evolving Digital Libraries

NASA Astrophysics Data System (ADS)

Clark, D.; Miller, S. P.; Peckman, U.; Smith, J.; Aerni, S.; Helly, J.; Sutton, D.; Chase, A.

2003-12-01

What began two years ago as an effort to stabilize the Scripps Institution of Oceanography (SIO) data archives from more than 700 cruises going back 50 years, has now become the operational fully-searchable "SIOExplorer" digital library, complete with thousands of historic photographs, images, maps, full text documents, binary data files, and 3D visualization experiences, totaling nearly 2 terabytes of digital content. Coping with data diversity and complexity has proven to be more challenging than dealing with large volumes of digital data. SIOExplorer has been built with scalability in mind, so that the addition of new data types and entire new collections may be accomplished with ease. It is a federated system, currently interoperating with three independent data-publishing authorities, each responsible for their own quality control, metadata specifications, and content selection. The IT architecture implemented at the San Diego Supercomputer Center (SDSC) streamlines the integration of additional projects in other disciplines with a suite of metadata management and collection building tools for "arbitrary digital objects." Metadata are automatically harvested from data files into domain-specific metadata blocks, and mapped into various specification standards as needed. Metadata can be browsed and objects can be viewed onscreen or downloaded for further analysis, with automatic proprietary-hold request management.

Networking of three dimensional sonography volume data.

PubMed

Kratochwil, A; Lee, A; Schoisswohl, A

2000-09-01

Three-dimensioned (3D) sonography enables the examiner to store, instead of copies from single B-scan planes, a volume consisting of 300 scan planes. The volume is displayed on a monitor in form of three orthogonal planes--longitudinal, axial and coronal. Translation and rotation facilitates anatomical orientation and provides any arbitrary plane within the volume to generate organ optimized scan planes. Different algorithms allow the extraction of different information such as surface, or bone structures by maximum mode, or fluid filled structures, such as vessels by the minimum mode. The volume may contain as well color information of vessels. The digitized information is stored on a magnetic optical disc. This allows virtual scanning in absence of the patient under the same conditions as the volume was primarily stored. The volume size is dependent on different, examiner-controlled settings. A volume may need a storage capacity between 2 and 16 MB of 8-bit gray level information. As such huge data sets are unsuitable for network transfer, data compression is of paramount interest. 100 stored volumes were submitted to JPEG, MPEG, and biorthogonal wavelet compression. The original and compressed volumes were randomly shown on two monitors. In case of noticeable image degradation, information on the location of the original and compressed volume and the ratio of compression was read. Numerical values for proving compression fidelity as pixel error calculation and computation of square root error have been unsuitable for evaluating image degradation. The best results in recognizing image degradation were achieved by image experts. The experts disagreed on the ratio where image degradation became visible in only 4% of the volumes. Wavelet compression ratios of 20:1 or 30:1 could be performed without discernible information reduction. The effect of volume compression is reflected both in the reduction of transfer time and in storage capacity. Transmission time for a volume of 6 MB using a normal telephone with a data flow of 56 kB/s was reduced from 14 min to 28 s at a compression rate of 30:1. Compression reduced storage requirements from 6 MB uncompressed to 200 kB at a compression rate of 30:1. This successful compression opens new possibilities of intra- and extra-hospital and global information for 3D sonography. The key to this communication is not only volume compression, but also the fact that the 3D examination can be simulated on any PC by the developed 3D software. PACS teleradiology using digitized radiographs transmitted over standard telephone lines. Systems in combination with the management systems of HIS and RIS are available for archiving, retrieval of images and reports and for local and global communication. This form of tele-medicine will have an impact on cost reduction in hospitals, reduction of transport costs. On this fundament worldwide education and multi-center studies becomes possible.

Automated 3D detection and classification of Giardia lamblia cysts using digital holographic microscopy with partially coherent source

NASA Astrophysics Data System (ADS)

El Mallahi, A.; Detavernier, A.; Yourassowsky, C.; Dubois, F.

2012-06-01

Over the past century, monitoring of Giardia lamblia became a matter of concern for all drinking water suppliers worldwide. Indeed, this parasitic flagellated protozoan is responsible for giardiasis, a widespread diarrhoeal disease (200 million symptomatic individuals) that can lead immunocompromised individuals to death. The major difficulty raised by Giardia lamblia's cyst, its vegetative transmission form, is its ability to survive for long periods in harsh environments, including the chlorine concentrations and treatment duration used traditionally in water disinfection. Currently, there is a need for a reliable, inexpensive, and easy-to-use sensor for the identification and quantification of cysts in the incoming water. For this purpose, we investigated the use of a digital holographic microscope working with partially coherent spatial illumination that reduces the coherent noise. Digital holography allows one to numerically investigate a volume by refocusing the different plane of depth of a hologram. In this paper, we perform an automated 3D analysis that computes the complex amplitude of each hologram, detects all the particles present in the whole volume given by one hologram and refocuses them if there are out of focus using a refocusing criterion based on the integrated complex amplitude modulus and we obtain the (x,y,z) coordinates of each particle. Then the segmentation of the particles is processed and a set of morphological and textures features characteristic to Giardia lamblia cysts is computed in order to classify each particles in the right classes.

Data management in NOAA

NASA Technical Reports Server (NTRS)

Callicott, William M.

1993-01-01

The NOAA archives contain 150 terabytes of data in digital form, most of which are the high volume GOES satellite image data. There are 630 data bases containing 2,350 environmental variables. There are 375 million film records and 90 million paper records in addition to the digital data base. The current data accession rate is 10 percent per year and the number of users are increasing at a 10 percent annual rate. NOAA publishes 5,000 publications and distributes over one million copies to almost 41,000 paying customers. Each year, over six million records are key entered from manuscript documents and about 13,000 computer tapes and 40,000 satellite hardcopy images are entered into the archive. Early digital data were stored on punched cards and open reel computer tapes. In the late seventies, an advanced helical scan technology (AMPEX TBM) was implemented. Now, punched cards have disappeared, the TBM system was abandoned, most data stored on open reel tapes have been migrated to 3480 cartridges, many specialized data sets were distributed on CD ROM's, special archives are being copied to 12 inch optical WORM disks, 5 1/4 inch magneto-optical disks were employed for workstation applications, and 8 mm EXABYTE tapes are planned for major data collection programs. The rapid expansion of new data sets, some of which constitute large volumes of data, coupled with the need for vastly improved access mechanisms, portability, and improved longevity are factors which will influence NOAA's future systems approaches for data management.

Taking digital imaging to the next level: challenges and opportunities.

PubMed

Hobbs, W Cecyl

2004-01-01

New medical imaging technology, such as multi-detector computed tomography (CT) scanners and positron emission tomography (PET) scanners, are creating new possibilities for non-invasive diagnosis that are leading providers to invest heavily in these new technologies. The volume of data produced by such technology is so large that it cannot be "read" using traditional film-based methods, and once in digital form, it creates a massive data integration and archiving challenge. Despite the benefits of digital imaging and archiving, there are several key challenges that healthcare organizations should consider in planning, selecting, and implementing the information technology (IT) infrastructure to support digital imaging. Decisions about storage and image distribution are essentially questions of "where" and "how fast." When planning the digital archiving infrastructure, organizations should think about where they want to store and distribute their images. This is similar to decisions that organizations have to make in regard to physical film storage and distribution, except the portability of images is even greater in a digital environment. The principle of "network effects" seems like a simple concept, yet the effect is not always considered when implementing a technology plan. To fully realize the benefits of digital imaging, the radiology department must integrate the archiving solutions throughout the department and, ultimately, with applications across other departments and enterprises. Medical institutions can derive a number of benefits from implementing digital imaging and archiving solutions like PACS. Hospitals and imaging centers can use the transition from film-based imaging as a foundational opportunity to reduce costs, increase competitive advantage, attract talent, and improve service to patients. The key factors in achieving these goals include attention to the means of data storage, distribution and protection.

Comparison of hand and semiautomatic tracing methods for creating maxillofacial artificial organs using sequences of computed tomography (CT) and cone beam computed tomography (CBCT) images.

PubMed

Szabo, Bence T; Aksoy, Seçil; Repassy, Gabor; Csomo, Krisztian; Dobo-Nagy, Csaba; Orhan, Kaan

2017-06-09

The aim of this study was to compare the paranasal sinus volumes obtained by manual and semiautomatic imaging software programs using both CT and CBCT imaging. 121 computed tomography (CT) and 119 cone beam computed tomography (CBCT) examinations were selected from the databases of the authors' institutes. The Digital Imaging and Communications in Medicine (DICOM) images were imported into 3-dimensonal imaging software, in which hand mode and semiautomatic tracing methods were used to measure the volumes of both maxillary sinuses and the sphenoid sinus. The determined volumetric means were compared to previously published averages. Isometric CBCT-based volume determination results were closer to the real volume conditions, whereas the non-isometric CT-based volume measurements defined coherently lower volumes. By comparing the 2 volume measurement modes, the values gained from hand mode were closer to the literature data. Furthermore, CBCT-based image measurement results corresponded to the known averages. Our results suggest that CBCT images provide reliable volumetric information that can be depended on for artificial organ construction, and which may aid the guidance of the operator prior to or during the intervention.

Contrast administration and techniques of digital subtraction angiography performance.

PubMed

Saddekni, S; Sos, T A; Srur, M; Cohn, D J

1985-06-01

Optimal IV-DSA performance depends equally on the digital system, the patient, and the radiologist. Through enhancement and subtraction, the digital system increases contrast sensitivity, thus compensating for the relatively low spatial resolution and for the loss in contrast (density) that results from dilution of the contrast medium by injecting it on the venous side. The degree of this dilution is governed by the patient's cardiac output and the size of the central blood volume. The lower the cardiac output and the larger the central blood volume, the less opacification (more dilution) and longer transit time (more likelihood for artifacts) will result. The role of the radiologist is to optimize the available conditions. He can prevent measures that decrease cardiac output (Valsalva maneuver) or he can take measures to decrease the degree of dilution by choosing optimal contrast administration methods, such as injecting in the right atrium at a high rate and thus allowing more latitude to decrease the total volume per injection and to increase the number of injections per examination. The radiologist also attempts to combat all the sources of noninformation or misinformation resulting from voluntary or involuntary patient motion, which degrades subtraction. By observing studies in real time, the radiologist may recognize motion during the injection, and by increasing the number of exposures, he may have a late mask to save the study. On immediate review of an injection, he may recognize the need to increase the volume per injection to obtain better opacification or, conversely, to reduce the volume if it is apparent that it could be done without compromise to the study and yet allow more injections to be performed, or he may recognize a finding that requires more than the usual routine views and may obtain a better one. IV-DSA can be performed with peripheral injections of contrast medium if the area of interest is limited and superior opacification is not essential, especially if a larger image intensifier (12- to 16-inch field) is available. However, whether peripheral injections are the least invasive, depends on whether one thinks that 200 to 240 ml of Renografin-76 for four views in an outpatient is invasive or not. The notion that IV-DSA can be performed by a nurse who places the IV needle or angiocatheter, a technician who shoots the pictures, and a computer that will do the rest, while the radiologist is peripherally involved and to hope for consistently good studies, is far from realistic.(ABSTRACT TRUNCATED AT 400 WORDS)

A Rapid Segmentation-Insensitive "Digital Biopsy" Method for Radiomic Feature Extraction: Method and Pilot Study Using CT Images of Non-Small Cell Lung Cancer.

PubMed

Echegaray, Sebastian; Nair, Viswam; Kadoch, Michael; Leung, Ann; Rubin, Daniel; Gevaert, Olivier; Napel, Sandy

2016-12-01

Quantitative imaging approaches compute features within images' regions of interest. Segmentation is rarely completely automatic, requiring time-consuming editing by experts. We propose a new paradigm, called "digital biopsy," that allows for the collection of intensity- and texture-based features from these regions at least 1 order of magnitude faster than the current manual or semiautomated methods. A radiologist reviewed automated segmentations of lung nodules from 100 preoperative volume computed tomography scans of patients with non-small cell lung cancer, and manually adjusted the nodule boundaries in each section, to be used as a reference standard, requiring up to 45 minutes per nodule. We also asked a different expert to generate a digital biopsy for each patient using a paintbrush tool to paint a contiguous region of each tumor over multiple cross-sections, a procedure that required an average of <3 minutes per nodule. We simulated additional digital biopsies using morphological procedures. Finally, we compared the features extracted from these digital biopsies with our reference standard using intraclass correlation coefficient (ICC) to characterize robustness. Comparing the reference standard segmentations to our digital biopsies, we found that 84/94 features had an ICC >0.7; comparing erosions and dilations, using a sphere of 1.5-mm radius, of our digital biopsies to the reference standard segmentations resulted in 41/94 and 53/94 features, respectively, with ICCs >0.7. We conclude that many intensity- and texture-based features remain consistent between the reference standard and our method while substantially reducing the amount of operator time required.

Digital mapping techniques '00, workshop proceedings - May 17-20, 2000, Lexington, Kentucky

USGS Publications Warehouse

Soller, David R.

2000-01-01

Introduction: The Digital Mapping Techniques '00 (DMT'00) workshop was attended by 99 technical experts from 42 agencies, universities, and private companies, including representatives from 28 state geological surveys (see Appendix A). This workshop was similar in nature to the first three meetings, held in June, 1997, in Lawrence, Kansas (Soller, 1997), in May, 1998, in Champaign, Illinois (Soller, 1998a), and in May, 1999, in Madison, Wisconsin (Soller, 1999). This year's meeting was hosted by the Kentucky Geological Survey, from May 17 to 20, 2000, on the University of Kentucky campus in Lexington. As in the previous meetings, the objective was to foster informal discussion and exchange of technical information. When, based on discussions at the workshop, an attendee adopts or modifies a newly learned technique, the workshop clearly has met that objective. Evidence of learning and cooperation among participating agencies continued to be a highlight of the DMT workshops (see example in Soller, 1998b, and various papers in this volume). The meeting's general goal was to help move the state geological surveys and the USGS toward development of more cost-effective, flexible, and useful systems for digital mapping and geographic information systems (GIS) analysis. Through oral and poster presentations and special discussion sessions, emphasis was given to: 1) methods for creating and publishing map products (here, 'publishing' includes Web-based release); 2) continued development of the National Geologic Map Database; 3) progress toward building a standard geologic map data model; 4) field data-collection systems; and 5) map citation and authorship guidelines. Four representatives of the GIS hardware and software vendor community were invited to participate. The four annual DMT workshops were coordinated by the AASG/USGS Data Capture Working Group, which was formed in August, 1996, to support the Association of American State Geologists and the USGS in their effort to build a National Geologic Map Database (see Soller and Berg, this volume, and http://ncgmp.usgs.gov/ngmdbproject/standards/datacapt/). The Working Group was formed because increased production efficiencies, standardization, and quality of digital map products were needed to help the Database, and the State and Federal geological surveys, provide more high-quality digital maps to the public.

Field test comparison of an autocorrelation technique for determining grain size using a digital 'beachball' camera versus traditional methods

USGS Publications Warehouse

Barnard, P.L.; Rubin, D.M.; Harney, J.; Mustain, N.

2007-01-01

This extensive field test of an autocorrelation technique for determining grain size from digital images was conducted using a digital bed-sediment camera, or 'beachball' camera. Using 205 sediment samples and >1200 images from a variety of beaches on the west coast of the US, grain size ranging from sand to granules was measured from field samples using both the autocorrelation technique developed by Rubin [Rubin, D.M., 2004. A simple autocorrelation algorithm for determining grain size from digital images of sediment. Journal of Sedimentary Research, 74(1): 160-165.] and traditional methods (i.e. settling tube analysis, sieving, and point counts). To test the accuracy of the digital-image grain size algorithm, we compared results with manual point counts of an extensive image data set in the Santa Barbara littoral cell. Grain sizes calculated using the autocorrelation algorithm were highly correlated with the point counts of the same images (r2 = 0.93; n = 79) and had an error of only 1%. Comparisons of calculated grain sizes and grain sizes measured from grab samples demonstrated that the autocorrelation technique works well on high-energy dissipative beaches with well-sorted sediment such as in the Pacific Northwest (r2 ??? 0.92; n = 115). On less dissipative, more poorly sorted beaches such as Ocean Beach in San Francisco, results were not as good (r2 ??? 0.70; n = 67; within 3% accuracy). Because the algorithm works well compared with point counts of the same image, the poorer correlation with grab samples must be a result of actual spatial and vertical variability of sediment in the field; closer agreement between grain size in the images and grain size of grab samples can be achieved by increasing the sampling volume of the images (taking more images, distributed over a volume comparable to that of a grab sample). In all field tests the autocorrelation method was able to predict the mean and median grain size with ???96% accuracy, which is more than adequate for the majority of sedimentological applications, especially considering that the autocorrelation technique is estimated to be at least 100 times faster than traditional methods.

Method for digital measurement of phase-frequency characteristics for a fixed-length ultrasonic spectrometer

NASA Astrophysics Data System (ADS)

Astashev, M. E.; Belosludtsev, K. N.; Kharakoz, D. P.

2014-05-01

One of the most accurate methods for measuring the compressibility of liquids is resonance measurement of sound velocity in a fixed-length interferometer. This method combines high sensitivity, accuracy, and small sample volume of the test liquid. The measuring principle is to study the resonance properties of a composite resonator that contains a test liquid sample. Ealier, the phase-locked loop (PLL) scheme was used for this. In this paper, we propose an alternative measurement scheme based on digital analysis of harmonic signals, describe the implementation of this scheme using commercially available data acquisition modules, and give examples of test measurements with accuracy evaluations of the results.

Numerical evaluation of the limit of concentration of colloidal samples for their study with digital lensless holographic microscopy.

PubMed

Restrepo, John F; Garcia-Sucerquia, Jorge

2013-01-01

The number of colloidal particles per unit of volume that can be imaged correctly with digital lensless holographic microscopy (DLHM) is determined numerically. Typical in-line DLHM holograms with controlled concentration are modeled and reconstructed numerically. By quantifying the ratio of the retrieved particles from the reconstructed hologram to the number of the seeding particles in the modeled intensity, the limit of concentration of the colloidal suspensions up to which DLHM can operate successfully is found numerically. A new shadow density parameter for spherical illumination is defined. The limit of performance of DLHM is determined from a graph of the shadow density versus the efficiency of the microscope.

A Database Management System Application for the Graduate Programs Office of the School of Systems and Logistics. Volume 2. Technical Reference Manual

DTIC Science & Technology

1988-09-01

CIT C 15 Name of local city. InCSrATE C 2 Name of local state as tw letter abbreviatiom. SIC ZIP C 10 Loa ZIP code. Five or nine digits . InC_ PHKtE C 15...record: 10 Database Dictimary for C: \\ BASE\\PAS1E.MF Field Nane Type Width Decimal Coments PMSCODE C 2 Third and fourth digits of PAS code. ON C 3...Version: 3.01 Date: 09/01/88 Time: 21:34 Report Libary : C: ASE\\GPO.RP1 Date: 08/28/88 Time: 11:32 PRMNT OFTICNS CflRL-PRINrM Nmber of copies: 1 Starting

The digital evolution of occupy wall street.

PubMed

Conover, Michael D; Ferrara, Emilio; Menczer, Filippo; Flammini, Alessandro

2013-01-01

We examine the temporal evolution of digital communication activity relating to the American anti-capitalist movement Occupy Wall Street. Using a high-volume sample from the microblogging site Twitter, we investigate changes in Occupy participant engagement, interests, and social connectivity over a fifteen month period starting three months prior to the movement's first protest action. The results of this analysis indicate that, on Twitter, the Occupy movement tended to elicit participation from a set of highly interconnected users with pre-existing interests in domestic politics and foreign social movements. These users, while highly vocal in the months immediately following the birth of the movement, appear to have lost interest in Occupy related communication over the remainder of the study period.

DIGIMEN, optical mass memory investigations, volume 2

NASA Technical Reports Server (NTRS)

1977-01-01

The DIGIMEM phase of the Optical Mass Memory Investigation Program addressed problems related to the analysis, design, and implementation of a direct digital optical recorder/reproducer. Effort was placed on developing an operational archival mass storage system to support one or more key NASA missions. The primary activity of the DIGIMEM program phase was the design, fabrication, and test and evaluation of a breadboard digital optical recorder/reproducer. Starting with technology and subsystem perfected during the HOLOMEM program phase, a fully operational optical spot recording breadboard that met or exceeded all program goals was evaluated. A thorough evaluation of several high resolution electrophotographic recording films was performed and a preliminary data base management/end user requirements survey was completed.

A digital computer program for the dynamic interaction simulation of controls and structure (DISCOS), volume 1

NASA Technical Reports Server (NTRS)

Bodley, C. S.; Devers, A. D.; Park, A. C.; Frisch, H. P.

1978-01-01

A theoretical development and associated digital computer program system for the dynamic simulation and stability analysis of passive and actively controlled spacecraft are presented. The dynamic system (spacecraft) is modeled as an assembly of rigid and/or flexible bodies not necessarily in a topological tree configuration. The computer program system is used to investigate total system dynamic characteristics, including interaction effects between rigid and/or flexible bodies, control systems, and a wide range of environmental loadings. In addition, the program system is used for designing attitude control systems and for evaluating total dynamic system performance, including time domain response and frequency domain stability analyses.

The Reliability of a Novel Mobile 3-dimensional Wound Measurement Device.

PubMed

Anghel, Ersilia L; Kumar, Anagha; Bigham, Thomas E; Maselli, Kathryn M; Steinberg, John S; Evans, Karen K; Kim, Paul J; Attinger, Christopher E

2016-11-01

Objective assessment of wound dimensions is essential for tracking progression and determining treatment effectiveness. A reliability study was designed to establish intrarater and interrater reliability of a novel mobile 3-dimensional wound measurement (3DWM) device. Forty-five wounds were assessed by 2 raters using a 3DWM device to obtain length, width, area, depth, and volume measurements. Wounds were also measured manually, using a disposable ruler and digital planimetry. The intraclass correlation coefficient (ICC) was used to establish intrarater and interrater reliability. High levels of intrarater and interrater agreement were observed for area, length, and width; ICC = 0.998, 0.977, 0.955 and 0.999, 0.997, 0.995, respectively. Moderate levels of intrarater (ICC = 0.888) and interrater (ICC = 0.696) agreement were observed for volume. Lastly, depth yielded an intrarater ICC of 0.360 and an interrater ICC of 0.649. Measures from the 3DWM device were highly correlated with those obtained from scaled photography for length, width, and area (ρ = 0.997, 0.988, 0.997, P < 0.001). The 3DWM device yielded correlations of ρ = 0.990, 0.987, 0.996 with P < 0.001 for length, width, and area when compared to manual measurements. The 3DWM device was found to be highly reliable for measuring wound areas for a range of wound sizes and types as compared to manual measurement and digital planimetry. The depth and therefore volume measurement using the 3DWM device was found to have a lower ICC, but volume ICC alone was moderate. Overall, this device offers a mobile option for objective wound measurement in the clinical setting.

VIPAR, a quantitative approach to 3D histopathology applied to lymphatic malformations

PubMed Central

Hägerling, René; Drees, Dominik; Scherzinger, Aaron; Dierkes, Cathrin; Martin-Almedina, Silvia; Butz, Stefan; Gordon, Kristiana; Schäfers, Michael; Hinrichs, Klaus; Vestweber, Dietmar; Goerge, Tobias; Mansour, Sahar; Mortimer, Peter S.

2017-01-01

BACKGROUND. Lack of investigatory and diagnostic tools has been a major contributing factor to the failure to mechanistically understand lymphedema and other lymphatic disorders in order to develop effective drug and surgical therapies. One difficulty has been understanding the true changes in lymph vessel pathology from standard 2D tissue sections. METHODS. VIPAR (volume information-based histopathological analysis by 3D reconstruction and data extraction), a light-sheet microscopy–based approach for the analysis of tissue biopsies, is based on digital reconstruction and visualization of microscopic image stacks. VIPAR allows semiautomated segmentation of the vasculature and subsequent nonbiased extraction of characteristic vessel shape and connectivity parameters. We applied VIPAR to analyze biopsies from healthy lymphedematous and lymphangiomatous skin. RESULTS. Digital 3D reconstruction provided a directly visually interpretable, comprehensive representation of the lymphatic and blood vessels in the analyzed tissue volumes. The most conspicuous features were disrupted lymphatic vessels in lymphedematous skin and a hyperplasia (4.36-fold lymphatic vessel volume increase) in the lymphangiomatous skin. Both abnormalities were detected by the connectivity analysis based on extracted vessel shape and structure data. The quantitative evaluation of extracted data revealed a significant reduction of lymphatic segment length (51.3% and 54.2%) and straightness (89.2% and 83.7%) for lymphedematous and lymphangiomatous skin, respectively. Blood vessel length was significantly increased in the lymphangiomatous sample (239.3%). CONCLUSION. VIPAR is a volume-based tissue reconstruction data extraction and analysis approach that successfully distinguished healthy from lymphedematous and lymphangiomatous skin. Its application is not limited to the vascular systems or skin. FUNDING. Max Planck Society, DFG (SFB 656), and Cells-in-Motion Cluster of Excellence EXC 1003. PMID:28814672

VIPAR, a quantitative approach to 3D histopathology applied to lymphatic malformations.

PubMed

Hägerling, René; Drees, Dominik; Scherzinger, Aaron; Dierkes, Cathrin; Martin-Almedina, Silvia; Butz, Stefan; Gordon, Kristiana; Schäfers, Michael; Hinrichs, Klaus; Ostergaard, Pia; Vestweber, Dietmar; Goerge, Tobias; Mansour, Sahar; Jiang, Xiaoyi; Mortimer, Peter S; Kiefer, Friedemann

2017-08-17

Lack of investigatory and diagnostic tools has been a major contributing factor to the failure to mechanistically understand lymphedema and other lymphatic disorders in order to develop effective drug and surgical therapies. One difficulty has been understanding the true changes in lymph vessel pathology from standard 2D tissue sections. VIPAR (volume information-based histopathological analysis by 3D reconstruction and data extraction), a light-sheet microscopy-based approach for the analysis of tissue biopsies, is based on digital reconstruction and visualization of microscopic image stacks. VIPAR allows semiautomated segmentation of the vasculature and subsequent nonbiased extraction of characteristic vessel shape and connectivity parameters. We applied VIPAR to analyze biopsies from healthy lymphedematous and lymphangiomatous skin. Digital 3D reconstruction provided a directly visually interpretable, comprehensive representation of the lymphatic and blood vessels in the analyzed tissue volumes. The most conspicuous features were disrupted lymphatic vessels in lymphedematous skin and a hyperplasia (4.36-fold lymphatic vessel volume increase) in the lymphangiomatous skin. Both abnormalities were detected by the connectivity analysis based on extracted vessel shape and structure data. The quantitative evaluation of extracted data revealed a significant reduction of lymphatic segment length (51.3% and 54.2%) and straightness (89.2% and 83.7%) for lymphedematous and lymphangiomatous skin, respectively. Blood vessel length was significantly increased in the lymphangiomatous sample (239.3%). VIPAR is a volume-based tissue reconstruction data extraction and analysis approach that successfully distinguished healthy from lymphedematous and lymphangiomatous skin. Its application is not limited to the vascular systems or skin. Max Planck Society, DFG (SFB 656), and Cells-in-Motion Cluster of Excellence EXC 1003.

Topology Analysis of the Sloan Digital Sky Survey. I. Scale and Luminosity Dependence

NASA Astrophysics Data System (ADS)

Park, Changbom; Choi, Yun-Young; Vogeley, Michael S.; Gott, J. Richard, III; Kim, Juhan; Hikage, Chiaki; Matsubara, Takahiko; Park, Myeong-Gu; Suto, Yasushi; Weinberg, David H.; SDSS Collaboration

2005-11-01

We measure the topology of volume-limited galaxy samples selected from a parent sample of 314,050 galaxies in the Sloan Digital Sky Survey (SDSS), which is now complete enough to describe the fully three-dimensional topology and its dependence on galaxy properties. We compare the observed genus statistic G(νf) to predictions for a Gaussian random field and to the genus measured for mock surveys constructed from new large-volume simulations of the ΛCDM cosmology. In this analysis we carefully examine the dependence of the observed genus statistic on the Gaussian smoothing scale RG from 3.5 to 11 h-1 Mpc and on the luminosity of galaxies over the range -22.50

The Utilization of Remotely Sensed Data to Analyze the Estimated Volume of Pyroclastic Deposits and Morphological Changes Caused by the 2010-2015 Eruption of Sinabung Volcano, North Sumatra, Indonesia

NASA Astrophysics Data System (ADS)

Yulianto, Fajar; Suwarsono; Sofan, Parwati

2016-08-01

In this research, remotely sensed data has been used to estimate the volume of pyroclastic deposits and analyze morphological changes that have resulted from the eruption of Sinabung volcano. Topographic information was obtained from these data and used for rapid mapping to assist in the emergency response. Topographic information and change analyses (pre- and syn- eruption) were conducted using digital elevation models (DEMs) for the period 2010-2015. Advanced spaceborne thermal emission and reflection radiometer (ASTER) global digital elevation model (GDEM) data from 2009 were used to generate the initial DEMs for the condition prior to the eruption of 2010. Satellite pour l'observation de la terre 6 (SPOT 6) stereo images acquired on 21 June 2015 and were used to make a DEM for that time. The results show that the estimated total volume of lava and pyroclastic deposits, produced during the period 2010 to mid-2015 is approximately 2.8 × 108 m3. This estimated volume of pyroclastic deposits can be used to predict the magnitude of future secondary lahar hazards, which are also related to the capacity of rivers in the area. Morphological changes are illustrated using cross-sectional analysis of the deposits, which are currently deposited to the east, southeast and south of the volcano. Such analyses can also help in forecasting the direction of the future flow hazards. The remote sensing and analysis methods used at Sinabung can also be applied at other volcanoes and to assess the threats of other types of hazards such as landslides and land subsidence.

Comparison of standard- and low-tube voltage 320-detector row volume CT angiography in detection of intracranial aneurysms with digital subtraction angiography as gold standard.

PubMed

Sun, Gang; Ding, Juan; Lu, Yang; Li, Min; Li, Li; Li, Guo-ying; Zhang, Xu-ping

2012-03-01

The aim of this study was to prospectively assess the effect of low-tube voltage (80 kVp) 320-detector row volume computed tomographic (CT) angiography (L-VCTA) in the detection of intracranial aneurysms, with three-dimensional (3D) spin digital subtraction angiography (DSA) as the gold standard. Forty-eight patients with clinically suspected subarachnoid hemorrhages were divided into two groups. One group underwent L-VCTA and DSA, while the other group underwent conventional-tube voltage (120 kVp) volume CT angiography (C-VCTA) and DSA. Vascular enhancement, image quality, detection accuracy of aneurysms, and radiation dose were compared between the two groups. For objective image quality, the L-VCTA group had higher mean vessel attenuation, correlated with higher image noise and lower signal-to-noise ratio, than the C-VCTA group. For subjective image quality, there were no significant differences between the two groups regarding scores for arterial enhancement, depiction of small arterial detail, interference of venous structures, and overall image quality scores. The mean effective dose for the L-VCTA group was significantly lower than for the C-VCTA group (0.56 ± 0.25 vs 1.84 ± 0.002 mSv), with a reduction of radiation dose of 69.73%. With 3D DSA as the reference standard, the sensitivity, specificity, and accuracy in the L-VCTA and C-VCTA groups were 94.12%, 100%, 94.4% and 100%, 100%, and 100%, respectively. In both groups, there were significant correlations for maximum aneurysm diameter measurements between volume CT angiography and 3D DSA; no statistical difference in the mean maximum diameter of each aneurysm was measured between volume CT angiography and 3D DSA. L-VCTA is helpful in detecting intracranial aneurysms, with results similar to those of 3D DSA, but at a lower radiation dose than C-VCTA. Copyright © 2012 AUR. Published by Elsevier Inc. All rights reserved.

Learning in Video Game Affinity Spaces. New Literacies and Digital Epistemologies. Volume 51

ERIC Educational Resources Information Center

Hayes, Elisabeth R., Ed.; Duncan, Sean C., Ed.

2012-01-01

As video games have become an important economic and cultural force, scholars are increasingly trying to better understand the ways that engagement with games may drive learning, literacy, and social participation in the twenty-first century. In this book, the authors consider games and just as importantly, the social interactions around games,…

A Computer Code for Dynamic Stress Analysis of Media-Structure Problems with Nonlinearities (SAMSON). Volume III. User’s Manual.

DTIC Science & Technology

NONLINEAR SYSTEMS, LINEAR SYSTEMS, SUBROUTINES , SOIL MECHANICS, INTERFACES, DYNAMICS, LOADS(FORCES), FORCE(MECHANICS), DAMPING, ACCELERATION, ELASTIC...PROPERTIES, PLASTIC PROPERTIES, CRACKS , REINFORCING MATERIALS , COMPOSITE MATERIALS , FAILURE(MECHANICS), MECHANICAL PROPERTIES, INSTRUCTION MANUALS, DIGITAL COMPUTERS...STRESSES, *COMPUTER PROGRAMS), (*STRUCTURES, STRESSES), (*DATA PROCESSING, STRUCTURAL PROPERTIES), SOILS , STRAIN(MECHANICS), MATHEMATICAL MODELS

North Jetty Performance and Entrance Navigation Channel Maintenance, Grays Harbor, Washington. Volume 2. Appendices

DTIC Science & Technology

2004-06-01

Rectified Infrared Aerial Photos Image112-4 flown on 9/9/01. F22 Appendix F Shoreline and Bathymetry Data Map registration and digitizing...Division 108( WW2 ), 163-179. Soulsby, R. L., and Whitehouse, R. J. S. W. (1997). “Threshold of sediment motion in coastal environments,” Proceeings

Scaling Solutions to Higher Education's Biggest Challenges: An NMC Horizon Project Strategic Brief. Volume 3.2

ERIC Educational Resources Information Center

Hall Giesinger, C.; Adams Becker, S.; Davis, A.; Shedd, L.

2016-01-01

Higher education is ripe for innovation. While emerging technological developments such as digital courseware and mobiles apps have made it easier than ever for people to engage with learning resources, significant issues of access and equity persist among students from low-income, minority, single-parent families, and other disadvantaged groups.…

A Research Program in Computer Technology. Volume 1

DTIC Science & Technology

1981-08-01

rigidity, sensor networks 10. command and control, digital voice communication, graphic input device for terminal, multimedia communications, portable...satellite channel in the internetwork environment; Distributed Sensor Networks - formulation of algorithms and communication protocols to support the...operation of geographically distributed sensors ; Personal Communicator - work intended to result in a demonstration-level portable terminal to test and

Fission meter

DOEpatents

Rowland, Mark S [Alamo, CA; Snyderman, Neal J [Berkeley, CA

2012-04-10

A neutron detector system for discriminating fissile material from non-fissile material wherein a digital data acquisition unit collects data at high rate, and in real-time processes large volumes of data directly into information that a first responder can use to discriminate materials. The system comprises counting neutrons from the unknown source and detecting excess grouped neutrons to identify fission in the unknown source.

Textile Messages: Dispatches from the World of E-Textiles and Education. New Literacies and Digital Epistemologies. Volume 62

ERIC Educational Resources Information Center

Buechley, Leah, Ed.; Peppler, Kylie, Ed.; Eisenberg, Michael, Ed.; Yasmin, Kafai, Ed.

2013-01-01

"Textile Messages" focuses on the emerging field of electronic textiles, or e-textiles--computers that can be soft, colorful, approachable, and beautiful. E-textiles are articles of clothing, home furnishings, or architectures that include embedded computational and electronic elements. This book introduces a collection of tools that…

Exploring the Digital Library: A Guide for Online Teaching and Learning

ERIC Educational Resources Information Center

Johnson, Kay; Magusin, Elaine

2005-01-01

This book, which is a volume in The Jossey-Bass Online Teaching and Learning series, addresses the key issue of library services for faculty and their students in the online learning environment. Written by librarians at Athabasca University, a leading institution in distance education, this book shows how faculty can effectively use digital…

Test Methods for Telemetry Systems and Subsystems. Volume 5: Test Methods for Digital Recorder/Reproducer Systems and Recorder Memory Modules

DTIC Science & Technology

2016-09-26

serial communications program ( Hyper terminal) Configure METS for PCM 1 Mbps and MIL-STD-1553 10-Hz rate 4 Configure the host software to...Verify recorder stopped 44 Issue . LOOP . Verify recorder goes into record and play in read after write mode 45 Issue .STOP, Verify recorder

System Interconnections. A Survey of Technical Requirements for Broadband Cable Teleservices; Volume Five.

ERIC Educational Resources Information Center

McManamon, Peter M.

Several aspects of system interconnections are treated in this report. The interconnection of existing and future cable television (CATV) systems for two-way transfer of audio/video and digital data signals is surveyed. The concept of interconnection is explored relative to existing and proposed CATV systems and broadband teleservice networks,…

Yearbook of the National Society for the Study of Education. Volume 106, Issue 2

ERIC Educational Resources Information Center

Smolin, Louanne; Lawless, Kimberly; Dede, Chris; Jones, Steve; Johnson-Yale, Camille; Perez, Francisco Seoane; Schuler, Jessica; Pellegrino, James W.; Goldman, Susan R.; Bertenthal, Meryl; Lawless, Kimberly; Vrasidas, Charalambos; Glass, Gene V.; Haertel, Geneva D.; Means, Barbara; Penuel, William; Goldmann, Hilary; Warschauer, Mark; Tettegah, Sharon; Whang, Eun Won; Collins, Nakia; Taylor, Kona; Vasquez, Olga A.; Burbules, Nicholas C.

2007-01-01

There is little dispute that technology has transformed people's everyday lives. People shop online, download news in their iPods, communicate via text and video, take digital photos, and conduct all manner of personal and professional business via the Internet. While these technologies have afforded new opportunities to improve efficiency,…

Requirements for Information Professionals in a Digital Environment: Some Thoughts

ERIC Educational Resources Information Center

Ataman, Bekir Kemal

2009-01-01

Purpose: The purpose of this paper is to point out the increasing need to provide information professionals with a sound grounding in the technological aspects of their profession. Design/methodology/approach: The paper sets out by describing the sudden increase in volumes of information that confront our society, and then looks at how the younger…

Handbook of Research on Technology Tools for Real-World Skill Development (2 Volumes)

ERIC Educational Resources Information Center

Rosen, Yigel, Ed.; Ferrara, Steve, Ed.; Mosharraf, Maryam, Ed.

2016-01-01

Education is expanding to include a stronger focus on the practical application of classroom lessons in an effort to prepare the next generation of scholars for a changing world economy centered on collaborative and problem-solving skills for the digital age. "The Handbook of Research on Technology Tools for Real-World Skill Development"…

Predictive Mapping of Forest Attributes on the Fishlake National Forest

Treesearch

Tracey S. Frescino; Gretchen G. Moisen

2005-01-01

Forest land managers increasingly need maps of forest characteristics to aid in planning and management. A set of 30-m resolution maps was prepared for the Fishlake National Forest by modeling FIA plot variables as nonparametric functions of ancillary digital data. The set includes maps of volume, biomass, growth, stand age, size, crown cover, and various aspen...

Sketching up the Digital Duck

ERIC Educational Resources Information Center

Shafer, Kathryn G.; Severt, Gina; Olson, Zachary A.

2011-01-01

The fun thing about teaching measurement topics is allowing students to create three-dimensional objects from cardboard or paper and then to use them to calculate volume and surface area. The project described in this article is one that author Shafer has used for many years at the high school and college levels to reinforce the concepts of volume…

UrbanCrowns: an assessment and monitoring tool for urban trees

Treesearch

Matthew F. Winn; Philip A. Araman; Sang-Mook Lee

2011-01-01

UrbanCrowns is a Windows®-based computer program used to assess the crown characteristics of urban trees. The software analyzes side-view digital photographs of trees to compute several crown metrics, including crown height, crown diameter, live crown ratio, crown volume, crown density, and crown transparency. Potential uses of the UrbanCrowns program include...

Discriminant musculo-skeletal leg characteristics between sprint and endurance elite Caucasian runners.

PubMed

Bex, T; Iannaccone, F; Stautemas, J; Baguet, A; De Beule, M; Verhegghe, B; Aerts, P; De Clercq, D; Derave, W

2017-03-01

Excellence in either sprinting or endurance running requires specific musculo-skeletal characteristics of the legs. This study aims to investigate the morphology of the leg of sprinters and endurance runners of Caucasian ethnicity. Eight male sprinters and 11 male endurance runners volunteered to participate in this cross-sectional study. They underwent magnetic resonance imaging and after data collection, digital reconstruction was done to calculate muscle volumes and bone lengths. Sprinters have a higher total upper leg volume compared to endurance runners (7340 vs 6265 cm 3 ). Specifically, the rectus femoris, vastus lateralis, and hamstrings showed significantly higher muscle volumes in the sprint group. For the lower leg, only a higher muscle volume was found in the gastrocnemius lateralis for the sprinters. No differences were found in muscle volume distribution, center of mass in the different muscles, or relative bone lengths. There was a significant positive correlation between ratio hamstrings/quadriceps volume and best running performance in the sprint group. Sprinters and endurance runners of Caucasian ethnicity showed the greatest distinctions in muscle volumes, rather than in muscle distributions or skeletal measures. Sprinters show higher volumes in mainly the proximal and lateral leg muscles than endurance runners. © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Digital PCR Modeling for Maximal Sensitivity, Dynamic Range and Measurement Precision

PubMed Central

Majumdar, Nivedita; Wessel, Thomas; Marks, Jeffrey

2015-01-01

The great promise of digital PCR is the potential for unparalleled precision enabling accurate measurements for genetic quantification. A challenge associated with digital PCR experiments, when testing unknown samples, is to perform experiments at dilutions allowing the detection of one or more targets of interest at a desired level of precision. While theory states that optimal precision (Po) is achieved by targeting ~1.59 mean copies per partition (λ), and that dynamic range (R) includes the space spanning one positive (λL) to one negative (λU) result from the total number of partitions (n), these results are tempered for the practitioner seeking to construct digital PCR experiments in the laboratory. A mathematical framework is presented elucidating the relationships between precision, dynamic range, number of partitions, interrogated volume, and sensitivity in digital PCR. The impact that false reaction calls and volumetric variation have on sensitivity and precision is next considered. The resultant effects on sensitivity and precision are established via Monte Carlo simulations reflecting the real-world likelihood of encountering such scenarios in the laboratory. The simulations provide insight to the practitioner on how to adapt experimental loading concentrations to counteract any one of these conditions. The framework is augmented with a method of extending the dynamic range of digital PCR, with and without increasing n, via the use of dilutions. An example experiment demonstrating the capabilities of the framework is presented enabling detection across 3.33 logs of starting copy concentration. PMID:25806524

A panning DLT procedure for three-dimensional videography.

PubMed

Yu, B; Koh, T J; Hay, J G

1993-06-01

The direct linear transformation (DLT) method [Abdel-Aziz and Karara, APS Symposium on Photogrammetry. American Society of Photogrammetry, Falls Church, VA (1971)] is widely used in biomechanics to obtain three-dimensional space coordinates from film and video records. This method has some major shortcomings when used to analyze events which take place over large areas. To overcome these shortcomings, a three-dimensional data collection method based on the DLT method, and making use of panning cameras, was developed. Several small single control volumes were combined to construct a large total control volume. For each single control volume, a regression equation (calibration equation) is developed to express each of the 11 DLT parameters as a function of camera orientation, so that the DLT parameters can then be estimated from arbitrary camera orientations. Once the DLT parameters are known for at least two cameras, and the associated two-dimensional film or video coordinates of the event are obtained, the desired three-dimensional space coordinates can be computed. In a laboratory test, five single control volumes (in a total control volume of 24.40 x 2.44 x 2.44 m3) were used to test the effect of the position of the single control volume on the accuracy of the computed three dimensional space coordinates. Linear and quadratic calibration equations were used to test the effect of the order of the equation on the accuracy of the computed three dimensional space coordinates. For four of the five single control volumes tested, the mean resultant errors associated with the use of the linear calibration equation were significantly larger than those associated with the use of the quadratic calibration equation. The position of the single control volume had no significant effect on the mean resultant errors in computed three dimensional coordinates when the quadratic calibration equation was used. Under the same data collection conditions, the mean resultant errors in the computed three dimensional coordinates associated with the panning and stationary DLT methods were 17 and 22 mm, respectively. The major advantages of the panning DLT method lie in the large image sizes obtained and in the ease with which the data can be collected. The method also has potential for use in a wide variety of contexts. The major shortcoming of the method is the large amount of digitizing necessary to calibrate the total control volume. Adaptations of the method to reduce the amount of digitizing required are being explored.

Digital versus conventional implant impressions for edentulous patients: accuracy outcomes.

PubMed

Papaspyridakos, Panos; Gallucci, German O; Chen, Chun-Jung; Hanssen, Stijn; Naert, Ignace; Vandenberghe, Bart

2016-04-01

To compare the accuracy of digital and conventional impression techniques for completely edentulous patients and to determine the effect of different variables on the accuracy outcomes. A stone cast of an edentulous mandible with five implants was fabricated to serve as master cast (control) for both implant- and abutment-level impressions. Digital impressions (n = 10) were taken with an intraoral optical scanner (TRIOS, 3shape, Denmark) after connecting polymer scan bodies. For the conventional polyether impressions of the master cast, a splinted and a non-splinted technique were used for implant-level and abutment-level impressions (4 cast groups, n = 10 each). Master casts and conventional impression casts were digitized with an extraoral high-resolution scanner (IScan D103i, Imetric, Courgenay, Switzerland) to obtain digital volumes. Standard tessellation language (STL) datasets from the five groups of digital and conventional impressions were superimposed with the STL dataset from the master cast to assess the 3D (global) deviations. To compare the master cast with digital and conventional impressions at the implant level, analysis of variance (ANOVA) and Scheffe's post hoc test was used, while Wilcoxon's rank-sum test was used for testing the difference between abutment-level conventional impressions. Significant 3D deviations (P < 0.001) were found between Group II (non-splinted, implant level) and control. No significant differences were found between Groups I (splinted, implant level), III (digital, implant level), IV (splinted, abutment level), and V (non-splinted, abutment level) compared with the control. Implant angulation up to 15° did not affect the 3D accuracy of implant impressions (P > 0.001). Digital implant impressions are as accurate as conventional implant impressions. The splinted, implant-level impression technique is more accurate than the non-splinted one for completely edentulous patients, whereas there was no difference in the accuracy at the abutment level. The implant angulation up to 15° did not affect the accuracy of implant impressions. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Site Environmental Report for 2009, Volume 2

DOE Office of Scientific and Technical Information (OSTI.GOV)

Xu, Suying

2010-08-19

Volume II of the Site Environmental Report for 2009 is provided by Ernest Orlando Lawrence Berkeley National Laboratory as a supplemental appendix to Volume I, which contains the body of the report. Volume II contains the environmental monitoring and sampling data used to generate summary results of routine and nonroutine sampling at the Laboratory, except for groundwater sampling data, which may be found in the reports referred to in Chapter 4 of Volume I. The results from sample collections are more comprehensive in Volume II than in Volume I: for completeness, all results from sample collections that began or endedmore » in calendar year (CY) 2009 are included in this volume. However, the samples representing CY 2008 data have not been used in the summary results that are reported in Volume I. (For example, although ambient air samples collected on January 6, 2009, are presented in Volume II, they represent December 2008 data and are not included in Table 4-2 in Volume I.) When appropriate, sampling results are reported in both conventional and International System (SI) units. For some results, the rounding procedure used in data reporting may result in apparent differences between the numbers reported in SI and conventional units. (For example, stack air tritium results reported as < 1.5 Bq/m3 are shown variously as < 39 and < 41 pCi/m3. Both of these results are rounded correctly to two significant digits.)« less

A review of Education and Social Media using conflict and functionalist theories

NASA Astrophysics Data System (ADS)

Cian, Heidi; Amann, Holly

2017-09-01

Education and Social Media: Toward a Digital Future (2016), edited by Christine Greenhow, Julia Sonnevend, and Colin Agur, is a compilation of essays by leading contributors to the digital and social media movement in education. The chapters within this volume provide a granular look at the current landscape of how digital media is utilized across educational levels, fields of study, and geographic areas. The book is divided into three sections discussing the emerging use of social media in education, challenges in its implementation, and potential directions as tech-based education continues to evolve. In this review, we situate the ideas presented in Education and Social Media in the functionalist and conflict theories of educational perspective to further illuminate the potential of digital learning in supporting increased access to education for marginalized student populations. We discuss how these competing views are both given voice in Education and Social Media, prompting the reader to critically reflect on advantages and dangers presented by increased use of technological platforms in educational settings. Topics discussed include online universities, peer-developed curriculum, and differential use of technology based on school socioeconomic demographics. We also suggest areas that have emerged in need of further discussion since the book's publication.

Point spread function based classification of regions for linear digital tomosynthesis

NASA Astrophysics Data System (ADS)

Israni, Kenny; Avinash, Gopal; Li, Baojun

2007-03-01

In digital tomosynthesis, one of the limitations is the presence of out-of-plane blur due to the limited angle acquisition. The point spread function (PSF) characterizes blur in the imaging volume, and is shift-variant in tomosynthesis. The purpose of this research is to classify the tomosynthesis imaging volume into four different categories based on PSF-driven focus criteria. We considered linear tomosynthesis geometry and simple back projection algorithm for reconstruction. The three-dimensional PSF at every pixel in the imaging volume was determined. Intensity profiles were computed for every pixel by integrating the PSF-weighted intensities contained within the line segment defined by the PSF, at each slice. Classification rules based on these intensity profiles were used to categorize image regions. At background and low-frequency pixels, the derived intensity profiles were flat curves with relatively low and high maximum intensities respectively. At in-focus pixels, the maximum intensity of the profiles coincided with the PSF-weighted intensity of the pixel. At out-of-focus pixels, the PSF-weighted intensity of the pixel was always less than the maximum intensity of the profile. We validated our method using human observer classified regions as gold standard. Based on the computed and manual classifications, the mean sensitivity and specificity of the algorithm were 77+/-8.44% and 91+/-4.13% respectively (t=-0.64, p=0.56, DF=4). Such a classification algorithm may assist in mitigating out-of-focus blur from tomosynthesis image slices.

Do CAD/CAM dentures really release less monomer than conventional dentures?

PubMed

Steinmassl, Patricia-Anca; Wiedemair, Verena; Huck, Christian; Klaunzer, Florian; Steinmassl, Otto; Grunert, Ingrid; Dumfahrt, Herbert

2017-06-01

Computer-aided design (CAD)/computer-aided manufacturing (CAM) dentures are assumed to have more favourable material properties than conventionally fabricated dentures, among them a lower methacrylate monomer release. The aim of this study was to test this hypothesis. CAD/CAM dentures were generated from ten different master casts by using four different CAD/CAM systems. Conventional, heat-polymerised dentures served as control group. Denture weight and volume were measured; the density was calculated, and the denture surface area was assessed digitally. The monomer release after 7 days of water storage was measured by high-performance liquid chromatography. Whole You Nexteeth and Wieland Digital Dentures had significantly lower mean volume and weight than conventional dentures. Baltic Denture System and Whole You Nexteeth had a significantly increased density. Baltic Denture System had a significantly smaller surface area. None of the CAD/CAM dentures released significantly less monomer than the control group. All tested dentures released very low amounts of methacrylate monomer, but not significantly less than conventional dentures. A statistically significant difference might nevertheless exist in comparison to other, less recommendable denture base materials, such as the frequently used autopolymerising resins. CAD/CAM denture fabrication has numerous advantages. It enables the fabrication of dentures with lower resin volume and lower denture weight. Both could increase the patient comfort. Dentures with higher density might exhibit more favourable mechanical properties. The hypothesis that CAD/CAM dentures release less monomer than conventional dentures could, however, not be verified.

Memory Network For Distributed Data Processors

NASA Technical Reports Server (NTRS)

Bolen, David; Jensen, Dean; Millard, ED; Robinson, Dave; Scanlon, George

1992-01-01

Universal Memory Network (UMN) is modular, digital data-communication system enabling computers with differing bus architectures to share 32-bit-wide data between locations up to 3 km apart with less than one millisecond of latency. Makes it possible to design sophisticated real-time and near-real-time data-processing systems without data-transfer "bottlenecks". This enterprise network permits transmission of volume of data equivalent to an encyclopedia each second. Facilities benefiting from Universal Memory Network include telemetry stations, simulation facilities, power-plants, and large laboratories or any facility sharing very large volumes of data. Main hub of UMN is reflection center including smaller hubs called Shared Memory Interfaces.

Investigation, development and application of optimal output feedback theory. Volume 2: Development of an optimal, limited state feedback outer-loop digital flight control system for 3-D terminal area operation

NASA Technical Reports Server (NTRS)

Broussard, J. R.; Halyo, N.

1984-01-01

This report contains the development of a digital outer-loop three dimensional radio navigation (3-D RNAV) flight control system for a small commercial jet transport. The outer-loop control system is designed using optimal stochastic limited state feedback techniques. Options investigated using the optimal limited state feedback approach include integrated versus hierarchical control loop designs, 20 samples per second versus 5 samples per second outer-loop operation and alternative Type 1 integration command errors. Command generator tracking techniques used in the digital control design enable the jet transport to automatically track arbitrary curved flight paths generated by waypoints. The performance of the design is demonstrated using detailed nonlinear aircraft simulations in the terminal area, frequency domain multi-input sigma plots, frequency domain single-input Bode plots and closed-loop poles. The response of the system to a severe wind shear during a landing approach is also presented.

High-Throughput Method for Automated Colony and Cell Counting by Digital Image Analysis Based on Edge Detection

PubMed Central

Choudhry, Priya

2016-01-01

Counting cells and colonies is an integral part of high-throughput screens and quantitative cellular assays. Due to its subjective and time-intensive nature, manual counting has hindered the adoption of cellular assays such as tumor spheroid formation in high-throughput screens. The objective of this study was to develop an automated method for quick and reliable counting of cells and colonies from digital images. For this purpose, I developed an ImageJ macro Cell Colony Edge and a CellProfiler Pipeline Cell Colony Counting, and compared them to other open-source digital methods and manual counts. The ImageJ macro Cell Colony Edge is valuable in counting cells and colonies, and measuring their area, volume, morphology, and intensity. In this study, I demonstrate that Cell Colony Edge is superior to other open-source methods, in speed, accuracy and applicability to diverse cellular assays. It can fulfill the need to automate colony/cell counting in high-throughput screens, colony forming assays, and cellular assays. PMID:26848849

Technology Interventions to Manage Food Intake: Where Are We Now?

PubMed

Allman-Farinelli, Margaret; Gemming, Luke

2017-09-23

This review describes the state-of-the-art for dietary assessment using smartphone apps and digital technology and provides an update on the efficacy of technology-mediated interventions for dietary change. Technology has progressed from apps requiring entry of foods consumed, to digital imaging to provide food intake data. However, these methods rely on patients being active in data collection. The automated estimation of the volume and composition of every meal consumed globally is years away. The use of text messaging, apps, social media, and combinations of these for interventions is growing and proving effective for type 2 diabetes mellitus (T2DM). Effectiveness of text messaging for obesity management is improving and multicomponent interventions show promise. A stand-alone app is less likely to produce positive outcomes and social media is relatively unexplored. A concentrated effort will be needed to progress digital dietary assessment. Researcher-designed technology programs are producing positive outcomes for T2DM but further research is needed in the area of weight management.

Definition of the key target volume in radiosurgical management of arteriovenous malformations: a new dynamic concept based on angiographic circulation time.

PubMed

Valle, Ramiro Del; Zenteno, Marco; Jaramillo, José; Lee, Angel; De Anda, Salvador

2008-12-01

The cumulative experience worldwide indicates complete radiosurgical obliteration rates of brain arteriovenous malformations (AVMs) ranging from 35 to 90%. The purpose of this study was to propose a strategy to increase the obliteration rate for AVMs through the dynamic definition of the key target volume (KTV). A prospective series of patients harboring an AVM was assessed using digital subtraction angiography in which a digital counter was used to measure the several stages of the frame-by-frame circulation time. All the patients were analyzed using dynamic measurement planning to define the KTV, corresponding to the volume of the shunt with the least vascular resistance and the earliest venous drainage. All patients underwent catheter-based angiography, a subgroup was additionally assessed by means of a superselective catheterization, and among these a further subgroup received embolization. The shunts were also categorized according to their angioarchitectural type: fistulous, plexiform, or mixed. The authors applied the radiosurgery-based grading system (RBGS) as well to find a correlation with the obliteration rate. This series includes 44 patients treated by radiosurgery; global angiography was performed for all patients, including dynamic measurement planning. Eighty-four percent of them underwent superselective catheterization, and 50% of the total population underwent embolization. In the embolized arm of the study, the pretreatment volume was up to 120 ml. In patients with a single treatment, the mean volume was 8.5 ml, and the median volume was 6.95 +/- 4.56 ml (mean +/- standard deviation), with a KTV of up to 15 ml. For prospectively staged radiosurgery, the mean KTV was 28 ml. The marginal radiation dose was 18-22 Gy, with a mean of dose 20 Gy. The mean RBGS score was 1.70. The overall obliteration rate was 91%, including the repeated radiosurgery group (4 patients), in which 100% showed complete obliteration. The overall permanent deficit was 2 of 44 patients, 1 in each group. Dynamic definition of the KTV might increase the obliteration rate, even in complex AVMs, allowing the treatment of smaller volumes off the recruitment vessels (pseudonidus). By using this technique, the authors avoided double-blind treatment, where the neurosurgeon does not know precisely which type of lesion he or she is irradiating and the interventionalist does not know why and what he or she is embolizing.

Recent technology and usage of plastic lenses in image taking objectives

NASA Astrophysics Data System (ADS)

Yamaguchi, Susumu; Sato, Hiroshi; Mori, Nobuyoshi; Kiriki, Toshihiko

2005-09-01

Recently, plastic lenses produced by injection molding are widely used in image taking objectives for digital cameras, camcorders, and mobile phone cameras, because of their suitability for volume production and ease of obtaining an advantage of aspherical surfaces. For digital camera and camcorder objectives, it is desirable that there is no image point variation with the temperature change in spite of employing several plastic lenses. At the same time, due to the shrinking pixel size of solid-state image sensor, there is now a requirement to assemble lenses with high accuracy. In order to satisfy these requirements, we have developed 16 times compact zoom objective for camcorder and 3 times class folded zoom objectives for digital camera, incorporating cemented plastic doublet consisting of a positive lens and a negative lens. Over the last few years, production volumes of camera-equipped mobile phones have increased substantially. Therefore, for mobile phone cameras, the consideration of productivity is more important than ever. For this application, we have developed a 1.3-mega pixels compact camera module with macro function utilizing the advantage of a plastic lens that can be given mechanically functional shape to outer flange part. Its objective consists of three plastic lenses and all critical dimensions related to optical performance can be determined by high precise optical elements. Therefore this camera module is manufactured without optical adjustment in automatic assembling line, and achieves both high productivity and high performance. Reported here are the constructions and the technical topics of image taking objectives described above.

A wave superposition method formulated in digital acoustic space

NASA Astrophysics Data System (ADS)

Hwang, Yong-Sin

In this thesis, a new formulation of the Wave Superposition method is proposed wherein the conventional mesh approach is replaced by a simple 3-D digital work space that easily accommodates shape optimization for minimizing or maximizing radiation efficiency. As sound quality is in demand in almost all product designs and also because of fierce competition between product manufacturers, faster and accurate computational method for shape optimization is always desired. Because the conventional Wave Superposition method relies solely on mesh geometry, it cannot accommodate fast shape changes in the design stage of a consumer product or machinery, where many iterations of shape changes are required. Since the use of a mesh hinders easy shape changes, a new approach for representing geometry is introduced by constructing a uniform lattice in a 3-D digital work space. A voxel (a portmanteau, a new word made from combining the sound and meaning, of the words, volumetric and pixel) is essentially a volume element defined by the uniform lattice, and does not require separate connectivity information as a mesh element does. In the presented method, geometry is represented with voxels that can easily adapt to shape changes, therefore it is more suitable for shape optimization. The new method was validated by computing radiated sound power of structures of simple and complex geometries and complex mode shapes. It was shown that matching volume velocity is a key component to an accurate analysis. A sensitivity study showed that it required at least 6 elements per acoustic wavelength, and a complexity study showed a minimal reduction in computational time.

Concordance of Commercial Data Sources for Neighborhood-Effects Studies

PubMed Central

Schootman, Mario

2010-01-01

Growing evidence supports a relationship between neighborhood-level characteristics and important health outcomes. One source of neighborhood data includes commercial databases integrated with geographic information systems to measure availability of certain types of businesses or destinations that may have either favorable or adverse effects on health outcomes; however, the quality of these data sources is generally unknown. This study assessed the concordance of two commercial databases for ascertaining the presence, locations, and characteristics of businesses. Businesses in the St. Louis, Missouri area were selected based on their four-digit Standard Industrial Classification (SIC) codes and classified into 14 business categories. Business listings in the two commercial databases were matched by standardized business name within specified distances. Concordance and coverage measures were calculated using capture–recapture methods for all businesses and by business type, with further stratification by census-tract-level population density, percent below poverty, and racial composition. For matched listings, distance between listings and agreement in four-digit SIC code, sales volume, and employee size were calculated. Overall, the percent agreement was 32% between the databases. Concordance and coverage estimates were lowest for health-care facilities and leisure/entertainment businesses; highest for popular walking destinations, eating places, and alcohol/tobacco establishments; and varied somewhat by population density. The mean distance (SD) between matched listings was 108.2 (179.0) m with varying levels of agreement in four-digit SIC (percent agreement = 84.6%), employee size (weighted kappa = 0.63), and sales volume (weighted kappa = 0.04). Researchers should cautiously interpret findings when using these commercial databases to yield measures of the neighborhood environment. PMID:20480397

No Shelf Required: E-Books in Libraries

ERIC Educational Resources Information Center

Polanka, Sue, Ed.

2010-01-01

E-books have been around for more than 10 years but are still a relatively new phenomenon to many librarians and publishers. With the introduction of e-book readers, the e-book has become mainstream, with recent triple-digit annual increases in sales. But what place do they have in the library? In this volume, Sue Polanka brings together a variety…

Information Sciences Assessment for Asia and Australasia

DTIC Science & Technology

2009-10-16

entertainment and home services - Machine Translation for international cooperation - NLU + Affective Computing for education - Intelligent Optimization for...into an emotion. ETTS, embedded Mandarin, music retrieval. Also, research in areas of computer graphics, digital media processing  Intelligent...many from outside China, 40% in phase 2 Sales volume in 2007 130 * 100 million RMB SAP (1st), CITI, AIG, EDS, Capgemini, ILOG, Infosys, HCL, Sony

Blogging as Change: Transforming Science and Math Education through New Media Literacies. New Literacies and Digital Epistemologies. Volume 41

ERIC Educational Resources Information Center

Luehmann, April, Ed.; Borasi, Raffaella, Ed.

2011-01-01

New literacies have many functions in schools and learning, but science and mathematics education are among the contexts where their full potential has yet to be explored. This book both illustrates and critically analyzes the practice of blogging and its possibilities for fostering different ways of communicating, interacting, learning, and…

A two-step nearest neighbors algorithm using satellite imagery for predicting forest structure within species composition classes

Treesearch

Ronald E. McRoberts

2009-01-01

Nearest neighbors techniques have been shown to be useful for predicting multiple forest attributes from forest inventory and Landsat satellite image data. However, in regions lacking good digital land cover information, nearest neighbors selected to predict continuous variables such as tree volume must be selected without regard to relevant categorical variables such...

Ground-based digital imagery for tree stem analysis

Treesearch

Neil Clark; Daniel L. Schmoldt; Randolph H. Wynne; Matthew F. Winn; Philip A. Araman

2000-01-01

In the USA, a subset of permanent forest sample plots within each geographic region are intensively measured to obtain estimates of tree volume and products. The detailed field measurements required for this type of sampling are both time consuming and error prone. We are attempting to reduce both of these factors with the aid of a commercially-available solid-state...

Digital adaptive controllers for VTOL vehicles. Volume 2: Software documentation

NASA Technical Reports Server (NTRS)

Hartmann, G. L.; Stein, G.; Pratt, S. G.

1979-01-01

The VTOL approach and landing test (VALT) adaptive software is documented. Two self-adaptive algorithms, one based on an implicit model reference design and the other on an explicit parameter estimation technique were evaluated. The organization of the software, user options, and a nominal set of input data are presented along with a flow chart and program listing of each algorithm.

The Work of Play: Meaning-Making in Videogames. New Literacies and Digital Epistemologies. Volume 48

ERIC Educational Resources Information Center

Hung, Aaron Chia Yuan

2011-01-01

Some educational researchers claim that videogames can energize learning in both traditional and non-traditional contexts; cultivate skills more useful to a changing economy; and present information in ways more appealing to students. The notion of "serious games" dates back as early as the 1950s, but so far has failed to make a significant…

Advanced Avionic Systems for Multimission Applications. Volume I.

DTIC Science & Technology

1982-10-01

technical report are theoretical and in no way reflect Air Fortp-nwnpid qnftwRrp png ramc 19. KEY WORDS (Continue on reveree aide It neceeary and Identify...addressed (1) the Development & Evaluation of Advanced Digital Avionics System Architectures and (2) the Development of a Single Processor Synchronous...29 4.3.2 Memory Technologies . . . . . . . . . . . . . . . . . 30 4.3.3 BIU Technology . . . . . . . . . . . . . . . . . . . 33

Central fabrication: Carved positive assessment

PubMed Central

Sanders, Joan E; Severance, Michael R; Myers, Timothy R; Ciol, Marcia A

2015-01-01

In this research we investigated the degree of error during the carving phase of central fabrication of prosthetic sockets for people with limb amputation. Three different model shapes were ordered from each of ten central fabrication companies. Using an accurate custom mechanical digitizer and alignment algorithm, we digitized the models and then compared the model shapes with the electronic file shapes. Results showed that 24 of the 30 models had volumes larger than the electronic file shapes while 24 had volumes that were smaller. 29 of the 30 models were oversized at the proximal aspect of the tibial tuberosity and undersized at the patellar tendon and popliteal areas. This error would result in a socket that had less tibial tubercle relief than intended in addition to a larger anterior-posterior dimension than desired. Comparison of the model shapes with socket shapes assessed for nine of the companies in a previous study showed that for five of the companies the sockets were relatively undersized over the tibial crest and fibular head. The results indicate that the socket the prosthetist receives will not always fit as planned, and that errors in the carving process are a source of the discrepancies. PMID:21515893

Atlas of Relations Between Climatic Parameters and Distributions of Important Trees and Shrubs in North America - Alaska Species and Ecoregions

USGS Publications Warehouse

Thompson, Robert S.; Anderson, Katherine H.; Strickland, Laura E.; Shafer, Sarah L.; Pelltier, Richard T.; Bartlein, Patrick J.

2006-01-01

Climate is the primary factor in controlling the continental-scale distribution of plant species, although the relations between climatic parameters and species' ranges is only now beginning to be quantified. Preceding volumes of this atlas explored the continental-scale relations between climatic parameters and the distributions of woody plant species across all of the continent of North America. This volume presents similar information for important woody species, groups of species, and ecoregions in more detail for the State of Alaska. For these analyses, we constructed a 25-kilometer equal-area grid of modern climatic and bioclimatic parameters for North America from instrumental weather records. We obtained a digital representation of the geographic distribution of each species or ecoregion, either from a published source or by digitizing the published distributions ourselves. The presence or absence of each species or ecoregion was then determined for each point on the 25-kilometer grid, thus providing a basis for comparison of the climatic data with the geographic distribution of each species or ecoregion. The relations between climate and these distributions are presented in graphical and tabular form.

From the surface to volume: concepts for the next generation of optical-holographic data-storage materials.

PubMed

Bruder, Friedrich-Karl; Hagen, Rainer; Rölle, Thomas; Weiser, Marc-Stephan; Fäcke, Thomas

2011-05-09

Optical data storage has had a major impact on daily life since its introduction to the market in 1982. Compact discs (CDs), digital versatile discs (DVDs), and Blu-ray discs (BDs) are universal data-storage formats with the advantage that the reading and writing of the digital data does not require contact and is therefore wear-free. These formats allow convenient and fast data access, high transfer rates, and electricity-free data storage with low overall archiving costs. The driving force for development in this area is the constant need for increased data-storage capacity and transfer rate. The use of holographic principles for optical data storage is an elegant way to increase the storage capacity and the transfer rate, because by this technique the data can be stored in the volume of the storage material and, moreover, it can be optically processed in parallel. This Review describes the fundamental requirements for holographic data-storage materials and compares the general concepts for the materials used. An overview of the performance of current read-write devices shows how far holographic data storage has already been developed. Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Volume server: A scalable high speed and high capacity magnetic tape archive architecture with concurrent multi-host access

NASA Technical Reports Server (NTRS)

Rybczynski, Fred

1993-01-01

A major challenge facing data processing centers today is data management. This includes the storage of large volumes of data and access to it. Current media storage for large data volumes is typically off line and frequently off site in warehouses. Access to data archived in this fashion can be subject to long delays, errors in media selection and retrieval, and even loss of data through misplacement or damage to the media. Similarly, designers responsible for architecting systems capable of continuous high-speed recording of large volumes of digital data are faced with the challenge of identifying technologies and configurations that meet their requirements. Past approaches have tended to evaluate the combination of the fastest tape recorders with the highest capacity tape media and then to compromise technology selection as a consequence of cost. This paper discusses an architecture that addresses both of these challenges and proposes a cost effective solution based on robots, high speed helical scan tape drives, and large-capacity media.

Microfluidic devices for the controlled manipulation of small volumes

DOEpatents

Ramsey, J Michael [Knoxville, TN; Jacobson, Stephen C [Knoxville, TN

2003-02-25

A method for conducting a broad range of biochemical analyses or manipulations on a series of nano- to subnanoliter reaction volumes and an apparatus for carrying out the same are disclosed. The method and apparatus are implemented on a fluidic microchip to provide high serial throughput. The method and device of the invention also lend themselves to multiple parallel analyses and manipulation to provide greater throughput for the generation of biochemical information. In particular, the disclosed device is a microfabricated channel device that can manipulate nanoliter or subnanoliter biochemical reaction volumes in a controlled manner to produce results at rates of 1 to 10 Hz per channel. The individual reaction volumes are manipulated in serial fashion analogous to a digital shift register. The method and apparatus according to this invention have application to such problems as screening molecular or cellular targets using single beads from split-synthesis combinatorial libraries, screening single cells for RNA or protein expression, genetic diagnostic screening at the single cell level, or performing single cell signal transduction studies.

Microsatellite Digital Magnetometer SMILE - Present State and Future Trends

NASA Astrophysics Data System (ADS)

Belyayev, Serhiy; Ivchenko, Nickolay

2010-05-01

The fluxgate magnetometers (FGM) are probably the most widespread instruments used onboard spacecrafts for both scientific and service purposes. The recent trend to decrease the weight and size of the spacecrafts requires creating as small as possible but enough sensitive FGM. A joint Swedish-Ukrainian team made the development of such a magnetometer and as the result the Small Magnetometer In Low mass Experiment (SMILE) - a digital fluxgate microsatellite magnetometer - was created [1]. Majority of electronic units of this FGM were combined in a digital integrated circuit - a Field Programmable Gate Array (FPGA). The FPGA provides full processing (determined by a digital correlation algorithm) of amplified and digitized fluxgate sensor output signals and provides both FGM output data and feedback signals. Such digital design makes the instrument very flexible, reduces power consumption and opens possibilities for customization of the operation modes. It allows miniaturizing the electronic unit and, together with the smallest in the world low noise three-component fluxgate sensor with the side dimension of 20 mm and weight about 20 grams only, the small but enough sensitive space qualified FGM is created. SMILE magnetometer was successfully flown onboard the NASA Cascades-2 sounding rocket, and is to fly in the LAPLander package onboard the ESA REXUS-8 student sounding rocket [2]. Unfortunately, such a design of electronic circuit does not allow us to realize all possibilities of the miniature sensor. The separate tests of the sensor with highest-class analog electronics showed that its noise level may be reduced to as low value as 10…15 picoTesla at 1 Hz. Also the use of volume compensation in the sensor provides high geometrical stability of the axes and improved performance compared to component compensated sensors. The measured parameters appear to be comparable or even better than these of best stationary FGM and, if realized in small enough volume and weight, such a sensitive but small FGM could be a good candidate for planned Lunar missions where the weight is the major restriction factor. This stimulated further research in the direction of the analysis and elimination of noise sources of digital design, as well as of the optimization of FGM electronic circuit structure. The description of the obtained results of the electronic unit upgrade and recent FGM model tests are given and future improvement directions are discussed. These works are partially supported by NSAU contract No. 1499. References: 1. Åke Forslund, Serhiy Belyayev, Nickolay Ivchenko, Göran Olsson, Terry Edberg and Andriy Marusenkov, Miniaturized digital fluxgate magnetometer for small spacecraft applications 2008 Meas. Sci. Technol. 19 2. T. Sundberg, N. Ivchenko, D. Borglund, P. Ahlen, M. Gustavsson, C. Jonsson, J. Juhlen, O. Neunet, J. Sandstrom, E. Sund, M. Wartelski, C. Westlund, L. Xin, Small Recoverable Payload for Deployable Sounding Rocket Experiments. ESA Special Publication SP671

Quantifying Glacier Volume Change Using UAV-Derived Imagery and Structure from Motion Photogrammetry

NASA Astrophysics Data System (ADS)

Decker, C. R.; La Frenierre, J.

2017-12-01

Glaciers in the Tropical Andes, like those worldwide, are experiencing rapid ice volume loss due to climate change. Tropical areas are of significant interest in glacier studies because they are especially sensitive to climate change. Quantifying the rate of ice volume loss is important given their sensitivity to climate change and the importance of glacier meltwater for downstream human use. Past studies have found shrinking ice surfaces areas, but finding the actual rate of volume loss gives more information about how glaciers are reacting to climate change as well as the direct hydrological effects of ice volume loss. In this study we determined the rate of ice volume loss for a debris covered section of the Reschreiter Glacier and a portion of the clean ice tongue of the Hans Meyer Glacier on Volcán Chimborazo in Ecuador. Traditional geodetic approaches of measuring ice volume change, including the use of satellite-derived digital elevation models and airborne LIDAR, are difficult in this case due to the small size of Chimborazo's glaciers, frequently cloudy conditions, and limited local resources. Instead, we obtained imagery with an Unmanned Aerial Vehicle (UAV) and processed this imagery using Structure from Motion photogrammetry. Our results are used to evaluate the role of elevation and debris cover as Chimborazo's glaciers respond to climate change.

3D Pathology Volumetric Technique: A Method for Calculating Breast Tumour Volume from Whole-Mount Serial Section Images

PubMed Central

Clarke, G. M.; Murray, M.; Holloway, C. M. B.; Liu, K.; Zubovits, J. T.; Yaffe, M. J.

2012-01-01

Tumour size, most commonly measured by maximum linear extent, remains a strong predictor of survival in breast cancer. Tumour volume, proportional to the number of tumour cells, may be a more accurate surrogate for size. We describe a novel “3D pathology volumetric technique” for lumpectomies and compare it with 2D measurements. Volume renderings and total tumour volume are computed from digitized whole-mount serial sections using custom software tools. Results are presented for two lumpectomy specimens selected for tumour features which may challenge accurate measurement of tumour burden with conventional, sampling-based pathology: (1) an infiltrative pattern admixed with normal breast elements; (2) a localized invasive mass separated from the in situ component by benign tissue. Spatial relationships between key features (tumour foci, close or involved margins) are clearly visualized in volume renderings. Invasive tumour burden can be underestimated using conventional pathology, compared to the volumetric technique (infiltrative pattern: 30% underestimation; localized mass: 3% underestimation for invasive tumour, 44% for in situ component). Tumour volume approximated from 2D measurements (i.e., maximum linear extent), assuming elliptical geometry, was seen to overestimate volume compared to the 3D volumetric calculation (by a factor of 7x for the infiltrative pattern; 1.5x for the localized invasive mass). PMID:23320179

Digital image archiving: challenges and choices.

PubMed

Dumery, Barbara

2002-01-01

In the last five years, imaging exam volume has grown rapidly. In addition to increased image acquisition, there is more patient information per study. RIS-PACS integration and information-rich DICOM headers now provide us with more patient information relative to each study. The volume of archived digital images is increasing and will continue to rise at a steeper incline than film-based storage of the past. Many filmless facilities have been caught off guard by this increase, which has been stimulated by many factors. The most significant factor is investment in new digital and DICOM-compliant modalities. A huge volume driver is the increase in images per study from multi-slice technology. Storage requirements also are affected by disaster recovery initiatives and state retention mandates. This burgeoning rate of imaging data volume presents many challenges: cost of ownership, data accessibility, storage media obsolescence, database considerations, physical limitations, reliability and redundancy. There are two basic approaches to archiving--single tier and multi-tier. Each has benefits. With a single-tier approach, all the data is stored on a single media that can be accessed very quickly. A redundant copy of the data is then stored onto another less expensive media. This is usually a removable media. In this approach, the on-line storage is increased incrementally as volume grows. In a multi-tier approach, storage levels are set up based on access speed and cost. In other words, all images are stored at the deepest archiving level, which is also the least expensive. Images are stored on or moved back to the intermediate and on-line levels if they will need to be accessed more quickly. It can be difficult to decide what the best approach is for your organization. The options include RAIDs (redundant array of independent disks), direct attached RAID storage (DAS), network storage using RAIDs (NAS and SAN), removable media such as different types of tape, compact disks (CDs and DVDs) and magneto-optical disks (MODs). As you evaluate the various options for storage, it is important to consider both performance and cost. For most imaging enterprises, a single-tier archiving approach is the best solution. With the cost of hard drives declining, NAS is a very feasible solution today. It is highly reliable, offers immediate access to all exams, and easily scales as imaging volume grows. Best of all, media obsolescence challenges need not be of concern. For back-up storage, removable media can be implemented, with a smaller investment needed as it will only be used for a redundant copy of the data. There is no need to keep it online and available. If further system redundancy is desired, multiple servers should be considered. The multi-tier approach still has its merits for smaller enterprises, but with a detailed long-term cost of ownership analysis, NAS will probably still come out on top as the solution of choice for many imaging facilities.

Characterization of fluid flow by digital correlation of scattered light

NASA Technical Reports Server (NTRS)

Gilbert, John A.; Matthys, Donald R.

1989-01-01

The objective is to produce a physical system suitable for a space environment that can measure fluid velocities in a three-dimensional volume by the development of a particle correlation velocimetry technique. Experimental studies were conducted on a field test cell to demonstrate the suitability and accuracy of digital correlation techniques for measuring two-dimensional fluid flows. This objective was satisfied by: (1) the design of an appropriate illumination and detection system for making velocity measurements within a test cell; (2) the design and construction of a test cell; (3) the preliminary evaluations on fluid and seeding requirements; and (4) the performance of controlled tests using a multiple exposure correlation technique. This presentation is represented by viewgraphs with very little text.

The Digital Evolution of Occupy Wall Street

PubMed Central

Conover, Michael D.; Ferrara, Emilio; Menczer, Filippo; Flammini, Alessandro

2013-01-01

We examine the temporal evolution of digital communication activity relating to the American anti-capitalist movement Occupy Wall Street. Using a high-volume sample from the microblogging site Twitter, we investigate changes in Occupy participant engagement, interests, and social connectivity over a fifteen month period starting three months prior to the movement's first protest action. The results of this analysis indicate that, on Twitter, the Occupy movement tended to elicit participation from a set of highly interconnected users with pre-existing interests in domestic politics and foreign social movements. These users, while highly vocal in the months immediately following the birth of the movement, appear to have lost interest in Occupy related communication over the remainder of the study period. PMID:23734215

Coniferous forest classification and inventory using Landsat and digital terrain data

NASA Technical Reports Server (NTRS)

Franklin, J.; Logan, T. L.; Woodcock, C. E.; Strahler, A. H.

1986-01-01

Machine-processing techniques were used in a Forest Classification and Inventory System (FOCIS) procedure to extract and process tonal, textural, and terrain information from registered Landsat multispectral and digital terrain data. Using FOCIS as a basis for stratified sampling, the softwood timber volumes of the Klamath National Forest and Eldorado National Forest were estimated within standard errors of 4.8 and 4.0 percent, respectively. The accuracy of these large-area inventories is comparable to the accuracy yielded by use of conventional timber inventory methods, but, because of automation, the FOCIS inventories are more rapid (9-12 months compared to 2-3 years for conventional manual photointerpretation, map compilation and drafting, field sampling, and data processing) and are less costly.

Infective endocarditis detection through SPECT/CT images digital processing

NASA Astrophysics Data System (ADS)

Moreno, Albino; Valdés, Raquel; Jiménez, Luis; Vallejo, Enrique; Hernández, Salvador; Soto, Gabriel

2014-03-01

Infective endocarditis (IE) is a difficult-to-diagnose pathology, since its manifestation in patients is highly variable. In this work, it was proposed a semiautomatic algorithm based on SPECT images digital processing for the detection of IE using a CT images volume as a spatial reference. The heart/lung rate was calculated using the SPECT images information. There were no statistically significant differences between the heart/lung rates values of a group of patients diagnosed with IE (2.62+/-0.47) and a group of healthy or control subjects (2.84+/-0.68). However, it is necessary to increase the study sample of both the individuals diagnosed with IE and the control group subjects, as well as to improve the images quality.

Digital processing of mesoscale analysis and space sensor data

NASA Technical Reports Server (NTRS)

Hickey, J. S.; Karitani, S.

1985-01-01

The mesoscale analysis and space sensor (MASS) data management and analysis system on the research computer system is presented. The MASS data base management and analysis system was implemented on the research computer system which provides a wide range of capabilities for processing and displaying large volumes of conventional and satellite derived meteorological data. The research computer system consists of three primary computers (HP-1000F, Harris/6, and Perkin-Elmer 3250), each of which performs a specific function according to its unique capabilities. The overall tasks performed concerning the software, data base management and display capabilities of the research computer system in terms of providing a very effective interactive research tool for the digital processing of mesoscale analysis and space sensor data is described.

Near-to-eye electroholography via guided-wave acousto-optics for augmented reality

NASA Astrophysics Data System (ADS)

Jolly, Sundeep; Savidis, Nickolaos; Datta, Bianca; Smalley, Daniel; Bove, V. Michael

2017-03-01

Near-to-eye holographic displays act to directly project wavefronts into a viewer's eye in order to recreate 3-D scenes for augmented or virtual reality applications. Recently, several solutions for near-to-eye electroholography have been proposed based on digital spatial light modulators in conjunction with supporting optics, such as holographic waveguides for light delivery; however, such schemes are limited by the inherent low space-bandwidth product available with current digital SLMs. In this paper, we depict a fully monolithic, integrated optical platform for transparent near-to-eye holographic display requiring no supporting optics. Our solution employs a guided-wave acousto-optic spatial light modulator implemented in lithium niobate in conjunction with an integrated Bragg-regime reflection volume hologram.

High-capacity high-speed recording

NASA Astrophysics Data System (ADS)

Jamberdino, A. A.

1981-06-01

Continuing advances in wideband communications and information handling are leading to extremely large volume digital data systems for which conventional data storage techniques are becoming inadequate. The paper presents an assessment of alternative recording technologies for the extremely wideband, high capacity storage and retrieval systems currently under development. Attention is given to longitudinal and rotary head high density magnetic recording, laser holography in human readable/machine readable devices and a wideband recorder, digital optical disks, and spot recording in microfiche formats. The electro-optical technologies considered are noted to be capable of providing data bandwidths up to 1000 megabits/sec and total data storage capacities in the 10 to the 11th to 10 to the 12th bit range, an order of magnitude improvement over conventional technologies.

Development of a digital microfluidic platform for point of care testing

PubMed Central

Sista, Ramakrishna; Hua, Zhishan; Thwar, Prasanna; Sudarsan, Arjun; Srinivasan, Vijay; Eckhardt, Allen; Pollack, Michael; Pamula, Vamsee

2009-01-01

Point of care testing is playing an increasingly important role in improving the clinical outcome in health care management. The salient features of a point of care device are quick results, integrated sample preparation and processing, small sample volumes, portability, multifunctionality and low cost. In this paper, we demonstrate some of these salient features utilizing an electrowetting-based Digital Microfluidic platform. We demonstrate the performance of magnetic bead-based immunoassays (cardiac troponin I) on a digital microfluidic cartridge in less than 8 minutes using whole blood samples. Using the same microfluidic cartridge, a 40-cycle real-time polymerase chain reaction was performed within 12 minutes by shuttling a droplet between two thermal zones. We further demonstrate, on the same cartridge, the capability to perform sample preparation for bacterial and fungal infectious disease pathogens (methicillin-resistance Staphylococcus aureus and Candida albicans) and for human genomic DNA using magnetic beads. In addition to rapid results and integrated sample preparation, electrowetting-based digital microfluidic instruments are highly portable because fluid pumping is performed electronically. All the digital microfluidic chips presented here were fabricated on printed circuit boards utilizing mass production techniques that keep the cost of the chip low. Due to the modularity and scalability afforded by digital microfluidics, multifunctional testing capability, such as combinations within and between immunoassays, DNA amplification, and enzymatic assays, can be brought to the point of care at a relatively low cost because a single chip can be configured in software for different assays required along the path of care. PMID:19023472

Using irreversible compression in digital radiology: a preliminary study of the opinions of radiologists

NASA Astrophysics Data System (ADS)

Seeram, Euclid

2006-03-01

The large volumes of digital images produced by digital imaging modalities in Radiology have provided the motivation for the development of picture archiving and communication systems (PACS) in an effort to provide an organized mechanism for digital image management. The development of more sophisticated methods of digital image acquisition (Multislice CT and Digital Mammography, for example), as well as the implementation and performance of PACS and Teleradiology systems in a health care environment, have created challenges in the area of image compression with respect to storing and transmitting digital images. Image compression can be reversible (lossless) or irreversible (lossy). While in the former, there is no loss of information, the latter presents concerns since there is a loss of information. This loss of information from diagnostic medical images is of primary concern not only to radiologists, but also to patients and their physicians. In 1997, Goldberg pointed out that "there is growing evidence that lossy compression can be applied without significantly affecting the diagnostic content of images... there is growing consensus in the radiologic community that some forms of lossy compression are acceptable". The purpose of this study was to explore the opinions of expert radiologists, and related professional organizations on the use of irreversible compression in routine practice The opinions of notable radiologists in the US and Canada are varied indicating no consensus of opinion on the use of irreversible compression in primary diagnosis, however, they are generally positive on the notion of the image storage and transmission advantages. Almost all radiologists are concerned with the litigation potential of an incorrect diagnosis based on irreversible compressed images. The survey of several radiology professional and related organizations reveals that no professional practice standards exist for the use of irreversible compression. Currently, the only standard for image compression is stated in the ACR's Technical Standards for Teleradiology and Digital Image Management.

Software Assurance Curriculum Project Volume 1: Master of Software Assurance Reference Curriculum

DTIC Science & Technology

2010-08-01

activity by providing a check on the relevance and currency of the process used to develop the MSwA2010 curriculum content. Figure 2 is an expansion of...random oracle model, symmetric crypto primitives, modes of operations, asymmetric crypto primitives (Chapter 5) [16] Detailed design...encryption, public key encryption, digital signatures, message authentication codes, crypto protocols, cryptanalysis, and further detailed crypto

Envisioning New Technologies in Teacher Practice: Moving Forward, Circling Back Using a Teacher Action Research Approach. New Literacies and Digital Epistemologies. Volume 47

ERIC Educational Resources Information Center

Strong-Wilson, Teresa, Ed.

2012-01-01

How do classroom teachers envision new technologies within their practice? In the conversation on incorporating new technologies into classrooms, teachers are often sidelined. "Envisioning New Technologies in Teacher Practice" looks at the complex ways in which teachers move forward to embrace change as well as how they circle back, continually…

A Traditional Educational Practice Adapted for the Digital Age

ERIC Educational Resources Information Center

Nix, Elizabeth; Etheridge, Brian; Walsh, Paul

2014-01-01

This article describes the development of The King Years, a weekly seminar taught at the University of Baltimore (UB) by Taylor Branch, the scholar who won the Pulitzer Prize for the first volume of his trilogy on the Civil Rights era. The King Years represents a foot in the water for a campus seeking a slow yet innovative entry into the world of…

Design study for multi-channel tape recorder system, volume 1

NASA Technical Reports Server (NTRS)

1972-01-01

The means of storing multispectral, high resolution sensor data on an Earth observing satellite are studied. It is concluded that this is best done digitally on a multi-track, longitudinal, magnetic tape recorder. The machine proposed will store 8 X 10 to the 10th power bits of data on 1040 m of 51 mm-wide magnetic tape mounted on two co-planar reels.

Pedagogy in the Age of Media Control: Language Deception and Digital Democracy. Minding the Media: Critical Issues for Learning and Teaching. Volume 3

ERIC Educational Resources Information Center

Rosa, Joao J.; Rosa, Ricardo D.

2011-01-01

Supported by critical theoretical frameworks, this book is a purposeful engagement with bodies of knowledge rooted in popular culture, yet routinely excluded from "common sense" visions of curriculum. Aimed at teachers as well as teacher-educators, the book examines areas such as Disney, African American stand-up comedy, intersections of…

The 30/20 GHz fixed communications systems service demand assessment. Volume 2: Main report

NASA Technical Reports Server (NTRS)

Gamble, R. B.; Seltzer, H. R.; Speter, K. M.; Westheimer, M.

1979-01-01

A forecast of demand for telecommunications services through the year 2000 is presented with particular reference to demand for satellite communications. Estimates of demand are provided for voice, video, and data services and for various subcategories of these services. The results are converted to a common digital measure in terms of terabits per year and aggregated to obtain total demand projections.

A Visual Language for Situational Awareness

DTIC Science & Technology

2016-12-01

listening. The arrival of the information age has delivered the ability to transfer larger volumes of data at far greater rates. Wireless digital... wireless infrastructure for use in large-scale events where domestic power and private wireless networks are overloaded or unavailable. States should...lacking by responders using ANSI INCITS 415 symbols sets.226 When combined with the power of a wireless network, a situational awareness metalanguage is

A Study on the Effects of Variable Surface Area to Volume Ratio on Closed Bomb Burn Rates

DTIC Science & Technology

1985-10-01

chrarge amnplif ier. Data acquisition was madie onl a Nic -olet Explorer Ill digital oscilloscope, followed by dlata reduction on aI PUP 11/34 coimpiterA...of Tech Jet PropulsLon Laboratory 2 Thiokol Corporation ATTN: L. D. StrandElkton Division 4800 Oak Grove Drive ATL’N: R. Biddle PsdnC 10 Tec~h Lib

[Development of a continuous blood pressure monitoring and recording system].

PubMed

Zhang, Yang; Li, Yong; Gao, Shumei; Song, Yilin

2012-09-01

A small experimental system is constructed with working principle of continuous blood pressure monitoring based on the volume compensation method. The preliminary experimental results show that the system can collect blood pressure signals at the radial artery effectively. The digital PID algorithm can track the variation of blood pressure. And the accuracy of continuous blood pressure detecting achieve the level of same kind of product.

Botulinum Toxin Type A Injections in the Psoas Muscle of Children with Cerebral Palsy: Muscle Atrophy after Motor End Plate-Targeted Injections

ERIC Educational Resources Information Center

Van Campenhout, Anja; Verhaegen, Ann; Pans, Steven; Molenaers, Guy

2013-01-01

MEP targeting during BoNT-A injections has been demonstrated to improve outcome. Two injection techniques of the psoas muscle--proximal MEP targeting versus a widely used more distal injection technique--are compared using muscle volume assessment by digital MRI segmentation as outcome measure. Method: 7 spastic diplegic children received…

A simple bubble-flowmeter with quasicontinuous registration.

PubMed

Ludt, H; Herrmann, H D

1976-07-22

The construction of a simple bubble-flow-meter is described. The instrument has the following features: 1. automatic bubble injection, 2. precise measurement of the bubble passage time by a digital counter, 3. quasicontinuous registration of the flow rate, 4. alternative run with clear fluid (water) and coloured fluid (blood), 5. low volume, 6. closed measuring system for measurements in low and high pressure systems.

The Shock and Vibration Digest, Volume 17, Number 12

DTIC Science & Technology

1985-12-01

of the con- engineering guidelines is presented. Includ - tinuous analog signals represented digitally ed are details related to general test tailor...into current technology in more S. than 150 topic areas. Review articles include technical information from articles, reports, and unpublished...Turbulence was actually produce the noise. One is the once thought to be a random and chaotic traditional view that the turbulence is .. motion of

Strategic Studies Quarterly. Volume 9, Number 2. Summer 2015

DTIC Science & Technology

2015-01-01

disrupting financial markets. Among other indicators, China’s already deployed and future Type 094 Jin -ciass nuclear ballistic missile submarines (SSBN...on agility instead of brute force re- inforces traditional Chinese military thinking. Since Sun Tzu, the acme of skill has been winning without... mechanical (both political and technical) nature of digital developments. Given this, the nature of system constraints under a dif- ferent future

Detection And Mapping (DAM) package. Volume 4B: Software System Manual, part 2

NASA Technical Reports Server (NTRS)

Schlosser, E. H.

1980-01-01

Computer programs, graphic devices, and an integrated set of manual procedures designed for efficient production of precisely registered and formatted maps from digital data are presented. The software can be used on any Univac 1100 series computer. The software includes pre-defined spectral limits for use in classifying and mapping surface water for LANDSAT-1, LANDSAT-2, and LANDSAT-3.

MX Siting Investigation. Water Resources Program, Technical Summary Report. Volume II.

DTIC Science & Technology

1981-11-30

Selected digital computer techniques for groundwater resource evaluation, Illinois State Water Survey, Bulletin No. 55. Robinson, B. P., Thordarson , W., and...34, American Geophysical Union Transactions, v. 16. Thordarson , W., and Robinson, B. P., 1971, Wells and springs in California and Nevada within 100... Thordarson , W., 1975, Hydrogeologic and hydro- chemical framework, south-central Great Basin, Nevada- * California, with special reference to the Nevada

Use of 3-D digital subtraction rotational angiography during cardiac catheterization of infants and adults with congenital heart diseases.

PubMed

Surendran, Sushitha; Waller, B Rush; Elijovich, Lucas; Agrawal, Vijaykumar; Kuhls-Gilcrist, Andrew; Johnson, Jason; Fagan, Thomas; Sathanandam, Shyam K

2017-10-01

To compare image quality, radiation and contrast doses required to obtain 3D-Digital subtraction rotational angiography (3D-DSRA) with 3D-Digital rotational angiography (3D-DRA) in infants (children ≤ 2 years of age) and adults with congenital heart diseases (ACHD). 3D-DRA can be performed with radiation doses comparable to bi-plane cine-angiography. However, 3D-DRA in infants requires a large contrast volume. The resolution of 3D-DRA performed in ACHD patients is limited by their soft tissue density. We hypothesized that the use of 3D-DSRA could help alleviate these concerns. Radiation (DAP) and contrast doses required to obtain 3D-DSRA was compared with 3D-DRA in 15 age-, size-, and intervention-matched infants and 15 ACHD patients. The diagnostic quality and utility of these two modalities were scored by 4 qualified independent observers. Both in infants and adults, the median contrast volume for 3D-DSRA was lower than 3D-DRA (0.98 vs. 1.81 mL/kg; P < 0.001 and 0.92 vs. 1.4 mL/kg; P < 0.001, respectively) with an increased DAP (median: 188 vs. 128 cGy cm 2 ; P = 0.068 and 659 vs. 427 cGy cm 2 ; P = 0.045, respectively). The diagnostic quality and utility scores for rotational-angiography, and 3D-reconstruction were superior for 3D-DSRA (score = 94 vs. 80%, P = 0.03 and 90 vs.79%, P = 0.01, respectively) and equivalent for multi-planar-reformation and 3D-roadmapping in ACHD patients compared with 3D-DRA. All scores for both modalities were equivalent for infants. 3D-DSRA can be acquired using lower contrast volume with a mildly higher radiation dose than 3D-DRA in infants and ACHD patients. The diagnostic quality and utility scores for 3D-DSRA were higher in ACHD patients and equivalent for infants compared with 3D-DRA. © 2017 Wiley Periodicals, Inc.

What is the best way to contour lung tumors on PET scans? Multiobserver validation of a gradient-based method using a NSCLC digital PET phantom.

PubMed

Werner-Wasik, Maria; Nelson, Arden D; Choi, Walter; Arai, Yoshio; Faulhaber, Peter F; Kang, Patrick; Almeida, Fabio D; Xiao, Ying; Ohri, Nitin; Brockway, Kristin D; Piper, Jonathan W; Nelson, Aaron S

2012-03-01

To evaluate the accuracy and consistency of a gradient-based positron emission tomography (PET) segmentation method, GRADIENT, compared with manual (MANUAL) and constant threshold (THRESHOLD) methods. Contouring accuracy was evaluated with sphere phantoms and clinically realistic Monte Carlo PET phantoms of the thorax. The sphere phantoms were 10-37 mm in diameter and were acquired at five institutions emulating clinical conditions. One institution also acquired a sphere phantom with multiple source-to-background ratios of 2:1, 5:1, 10:1, 20:1, and 70:1. One observer segmented (contoured) each sphere with GRADIENT and THRESHOLD from 25% to 50% at 5% increments. Subsequently, seven physicians segmented 31 lesions (7-264 mL) from 25 digital thorax phantoms using GRADIENT, THRESHOLD, and MANUAL. For spheres <20 mm in diameter, GRADIENT was the most accurate with a mean absolute % error in diameter of 8.15% (10.2% SD) compared with 49.2% (51.1% SD) for 45% THRESHOLD (p < 0.005). For larger spheres, the methods were statistically equivalent. For varying source-to-background ratios, GRADIENT was the most accurate for spheres >20 mm (p < 0.065) and <20 mm (p < 0.015). For digital thorax phantoms, GRADIENT was the most accurate (p < 0.01), with a mean absolute % error in volume of 10.99% (11.9% SD), followed by 25% THRESHOLD at 17.5% (29.4% SD), and MANUAL at 19.5% (17.2% SD). GRADIENT had the least systematic bias, with a mean % error in volume of -0.05% (16.2% SD) compared with 25% THRESHOLD at -2.1% (34.2% SD) and MANUAL at -16.3% (20.2% SD; p value <0.01). Interobserver variability was reduced using GRADIENT compared with both 25% THRESHOLD and MANUAL (p value <0.01, Levene's test). GRADIENT was the most accurate and consistent technique for target volume contouring. GRADIENT was also the most robust for varying imaging conditions. GRADIENT has the potential to play an important role for tumor delineation in radiation therapy planning and response assessment. Copyright © 2012. Published by Elsevier Inc.

Evaluation of an Electrostatic Dust Removal System with Potential Application in Next-Step Fusion Devices

NASA Technical Reports Server (NTRS)

Friesen, F. Q. L.; John, B.; Skinner, C. H.; Roquemore, A. L.; Calle, C. I.

2011-01-01

The ability to manage inventories of carbon, tritium, and high-Z elements in fusion plasmas depends on means for effective dust removal. A dust conveyor, based on a moving electrostatic potential well, was tested with particles of tungsten, carbon, glass and sand. A digital microscope imaged a representative portion of the conveyor, and dust particle size and volume distributions were derived before and after operation. About 10 cu mm volume of carbon and tungsten particles were moved in under 5 seconds. The highest driving amplitude tested of 3 kV was the most effective. The optimal driving frequency was 210 Hz (maximum tested) for tungsten particles, decreasing to below 60 Hz for the larger sand particles. Measurements of particle size and volume distributions after 10 and 100 cycles show the breaking apart of agglomerated carbon, and the change in particle distribution over short timescales 1 s).

Correlation Characterization of Particles in Volume Based on Peak-to-Basement Ratio

PubMed Central

Vovk, Tatiana A.; Petrov, Nikolay V.

2017-01-01

We propose a new express method of the correlation characterization of the particles suspended in the volume of optically transparent medium. It utilizes inline digital holography technique for obtaining two images of the adjacent layers from the investigated volume with subsequent matching of the cross-correlation function peak-to-basement ratio calculated for these images. After preliminary calibration via numerical simulation, the proposed method allows one to quickly distinguish parameters of the particle distribution and evaluate their concentration. The experimental verification was carried out for the two types of physical suspensions. Our method can be applied in environmental and biological research, which includes analyzing tools in flow cytometry devices, express characterization of particles and biological cells in air and water media, and various technical tasks, e.g. the study of scattering objects or rapid determination of cutting tool conditions in mechanisms. PMID:28252020

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ranjanomennahary, P.; Ghalila, S. Sevestre; Malouche, D

Purpose: Hip fracture is a serious health problem and textural methods are being developed to assess bone quality. The authors aimed to perform textural analysis at femur on high-resolution digital radiographs compared to three-dimensional (3D) microarchitecture comparatively to bone mineral density. Methods: Sixteen cadaveric femurs were imaged with an x-ray device using a C-MOS sensor. One 17 mm square region of interest (ROI) was selected in the femoral head (FH) and one in the great trochanter (GT). Two-dimensional (2D) textural features from the co-occurrence matrices were extracted. Site-matched measurements of bone mineral density were performed. Inside each ROI, a 16more » mm diameter core was extracted. Apparent density (D{sub app}) and bone volume proportion (BV/TV{sub Arch}) were measured from a defatted bone core using Archimedes' principle. Microcomputed tomography images of the entire length of the core were obtained (Skyscan 1072) at 19.8 {mu}m of resolution and usual 3D morphometric parameters were computed on the binary volume after calibration from BV/TV{sub Arch}. Then, bone surface/bone volume, trabecular thickness, trabecular separation, and trabecular number were obtained by direct methods without model assumption and the structure model index was calculated. Results: In univariate analysis, the correlation coefficients between 2D textural features and 3D morphological parameters reached 0.83 at the FH and 0.79 at the GT. In multivariate canonical correlation analysis, coefficients of the first component reached 0.95 at the FH and 0.88 at the GT. Conclusions: Digital radiographs, widely available and economically viable, are an alternative method for evaluating bone microarchitectural structure.« less

Enabling Real-Time Volume Rendering of Functional Magnetic Resonance Imaging on an iOS Device.

PubMed

Holub, Joseph; Winer, Eliot

2017-12-01

Powerful non-invasive imaging technologies like computed tomography (CT), ultrasound, and magnetic resonance imaging (MRI) are used daily by medical professionals to diagnose and treat patients. While 2D slice viewers have long been the standard, many tools allowing 3D representations of digital medical data are now available. The newest imaging advancement, functional MRI (fMRI) technology, has changed medical imaging from viewing static to dynamic physiology (4D) over time, particularly to study brain activity. Add this to the rapid adoption of mobile devices for everyday work and the need to visualize fMRI data on tablets or smartphones arises. However, there are few mobile tools available to visualize 3D MRI data, let alone 4D fMRI data. Building volume rendering tools on mobile devices to visualize 3D and 4D medical data is challenging given the limited computational power of the devices. This paper describes research that explored the feasibility of performing real-time 3D and 4D volume raycasting on a tablet device. The prototype application was tested on a 9.7" iPad Pro using two different fMRI datasets of brain activity. The results show that mobile raycasting is able to achieve between 20 and 40 frames per second for traditional 3D datasets, depending on the sampling interval, and up to 9 frames per second for 4D data. While the prototype application did not always achieve true real-time interaction, these results clearly demonstrated that visualizing 3D and 4D digital medical data is feasible with a properly constructed software framework.

Image-based modeling of tumor shrinkage in head and neck radiation therapy1

PubMed Central

Chao, Ming; Xie, Yaoqin; Moros, Eduardo G.; Le, Quynh-Thu; Xing, Lei

2010-01-01

Purpose: Understanding the kinetics of tumor growth∕shrinkage represents a critical step in quantitative assessment of therapeutics and realization of adaptive radiation therapy. This article presents a novel framework for image-based modeling of tumor change and demonstrates its performance with synthetic images and clinical cases. Methods: Due to significant tumor tissue content changes, similarity-based models are not suitable for describing the process of tumor volume changes. Under the hypothesis that tissue features in a tumor volume or at the boundary region are partially preserved, the kinetic change was modeled in two steps: (1) Autodetection of homologous tissue features shared by two input images using the scale invariance feature transformation (SIFT) method; and (2) establishment of a voxel-to-voxel correspondence between the images for the remaining spatial points by interpolation. The correctness of the tissue feature correspondence was assured by a bidirectional association procedure, where SIFT features were mapped from template to target images and reversely. A series of digital phantom experiments and five head and neck clinical cases were used to assess the performance of the proposed technique. Results: The proposed technique can faithfully identify the known changes introduced when constructing the digital phantoms. The subsequent feature-guided thin plate spline calculation reproduced the “ground truth” with accuracy better than 1.5 mm. For the clinical cases, the new algorithm worked reliably for a volume change as large as 30%. Conclusions: An image-based tumor kinetic algorithm was developed to model the tumor response to radiation therapy. The technique provides a practical framework for future application in adaptive radiation therapy. PMID:20527569

Megarectum in constipation

PubMed Central

van der Plas, R N; Benninga, M; Staalman, C; Akkermans, L; Redekop, W; Taminiau, J; Buller, H

2000-01-01

BACKGROUND—Faecal impaction is frequently observed in children with chronic constipation. The term megarectum is often used to describe this finding.
AIM—To evaluate rectal functioning and rectal measures in constipated children with a filled rectum, in order to define the terms faecal impaction, enlarged rectum, and megarectum.
METHODS—All children underwent radiological investigation, colonic transit time study, anorectal manometry, and rectal volume and rectal wall compliance measurements. Patients with faecal impaction were compared with controls, who had an empty rectum on digital rectal examination.
RESULTS—A total of 31 patients and six controls were included in the study. The mean duration of complaints was 4.2 years and all had faecal incontinence. The colonic transit times in the patients showed a distinct delay in the rectosigmoid segment. Anorectal manometry was not significantly different between patients and controls. The rectal width in patients was 0.68 and in controls 0.52 with an upper limit of 0.61. The pressure-volume curve in patients showed significant less relaxation at a distension of 50 ml. The slope of the curve (corresponding with rectal wall compliance) was comparable for patients and controls.
CONCLUSIONS—We suggest that faecal impaction is a filled rectum found on digital rectal examination; an enlarged rectum is defined by a rectopelvic ratio greater than 0.61; and megarectum is defined in those with significant abnormalities found with anorectal manometry, pressure-volume curves, or rectal compliance investigation. A diminished relaxation of the rectum on rectal distension could be the first sign of megarectum in children with chronic constipation.

 PMID:10869000

Metrology to quantify wear and creep of polyethylene tibial knee inserts.

PubMed

Muratoglu, Orhun K; Perinchief, Rebecca S; Bragdon, Charles R; O'Connor, Daniel O; Konrad, Reto; Harris, William H

2003-05-01

Assessment of damage on articular surfaces of ultrahigh molecular weight polyethylene tibial knee inserts primarily has been limited to qualitative methods, such as visual observation and classification of features such as pitting, delamination, and subsurface cracking. Semiquantitative methods also have been proposed to determine the linear penetration and volume of the scar that forms on articular surfaces of tibial knee inserts. The current authors report a new metrologic method that uses a coordinate measuring machine to quantify the dimensions of this scar. The articular surface of the insert is digitized with the coordinate measuring machine before and after regular intervals of testing on a knee simulator. The volume and linear penetration of the scar are calculated by mathematically taking the difference between the digitized surface maps of the worn and unworn articular surfaces. Three conventional polyethylene tibial knee inserts of a posterior cruciate-sparing design were subjected to five million cycles of normal gait on a displacement-driven knee wear simulator in bovine serum. A metrologic method was used to calculate creep and wear contributions to the scar formation on each tibial plateau. Weight loss of the inserts was determined gravimetrically with the appropriate correction for fluid absorption. The total average wear volume was 43 +/- 9 and 41 +/- 4 mm3 measured by the metrologic and gravimetric methods, respectively. The wear rate averaged 8.3 +/- 0.9 and 8.5 +/- 1.6 mm3 per million cycles measured by the metrologic and gravimetric methods, respectively. These comparisons reflected strong agreement between the metrologic and gravimetric methods.

Acetate templating on digital images is more accurate than computer-based templating for total hip arthroplasty.

PubMed

Petretta, Robert; Strelzow, Jason; Ohly, Nicholas E; Misur, Peter; Masri, Bassam A

2015-12-01

Templating is an important aspect of preoperative planning for total hip arthroplasty and can help determine the size and positioning of the prosthesis. Historically, templating has been performed using acetate templates over printed radiographs. As a result of the increasing use of digital imaging, surgeons now either obtain additional printed radiographs solely for templating purposes or use specialized digital templating software, both of which carry additional cost. The purposes of this study was to compare acetate templating of digitally calibrated images on an LCD monitor to digital templating in terms of (1) accuracy; (2) reproducibility; and (3) time efficiency. Acetate onlay templating was performed directly over digital radiographs on an LCD monitor and was compared with digital templating. Five separate observers participated in this study templating on 52 total hip arthroplasties. For the acetate templating, the digital images were magnified to the scaled reference on the templates provided by the manufacturer (ratio 1.2:1) before templating using a 25-mm marker as a reference. Both the acetate and digital templating results were then compared with the actual implanted components to determine accuracy. Interobserver and intraobserver variability was determined by an intraclass correlation coefficient. Observers recorded time to complete templating from the time of complete upload of patients' imaging onto the system to completion of templating. Both acetate and digital templates demonstrated moderate accuracy in predicting within one size of the eventual implanted acetabular cup (77% [199 of 260]; 70% [181 of 260], respectively; p = 0.050; 95% confidence interval [CI], 0.058-0.32), whereas acetate templating was better at predicting the femoral stem compared to digital templating (75% [195 of 260]; 60% [155 of 260], respectively; p < 0.001; 95% CI, 0.084-0.32). Acetate templating showed moderate to substantial interobserver agreement (cup intraclass correlation coefficient [ICC] = 0.55; 95% CI, 0.14-0.86; femoral ICC = 0.75; 95% CI, 0.39-0.95) and both methods showed almost perfect intraobserver agreement in reproducibility (acetate cup ICC = 0.82; 95% CI, 0.66-0.97; acetate femoral ICC = 0.86; 95% CI, 0.74-0.97; digital cup ICC = 0.82; 95% CI, 0.68-0.97; digital femoral ICC = 0.88; 95% CI, 0.77-1.0). Acetate templating could be performed more quickly (acetate mean 119 seconds; range, 37-220 seconds versus 154 seconds; range, 73-343 seconds; p < 0.001). Acetate onlay templating on digitally calibrated images can be a reliable substitute for digital templating using specialized software. It is quicker to perform and much less expensive. Hospitals and practices need not purchase expensive software, particularly at lower volume centers. Level III, diagnostic study.

Advanced Detector and Waveform Digitizer for Water Vapor DIAL Systems

NASA Technical Reports Server (NTRS)

Refaat, Tamer F.; Luck, William S., Jr.; DeYoung, Russell J.

1998-01-01

Measurement of atmospheric water vapor has become a major requirement for understanding moist-air processes. Differential absorption lidar (DIAL) is a technique best suited for the measurement of atmospheric water vapor. NASA Langley Research Center is continually developing improved DIAL systems. One aspect of current development is focused on the enhancement of a DIAL receiver by applying state-of-the-art technology in building a new compact detection system that will be placed directly on the DIAL receiver telescope. The newly developed detection system has the capability of being digitally interfaced with a simple personal computer, using a discrete input/output interface. This has the potential of transmitting digital data over relatively long distances instead of analog signals, which greatly reduces measurement noise. In this paper, we discuss some results from the new compact water vapor DIAL detection system which includes a silicon based avalanche photodiode (APD) detector, a 14-bit, 10-MHz waveform digitizer, a microcontroller and other auxiliary electronics. All of which are contained on a small printed-circuit-board. This will significantly reduce the weight and volume over the current CAMAC system and eventually will be used in a water vapor DIAL system on an unpiloted atmospheric vehicle (UAV) aircraft, or alternatively on an orbiting spacecraft.

Dose assessment of digital tomosynthesis in pediatric imaging

NASA Astrophysics Data System (ADS)

Gislason, Amber; Elbakri, Idris A.; Reed, Martin

2009-02-01

We investigated the potential for digital tomosynthesis (DT) to reduce pediatric x-ray dose while maintaining image quality. We utilized the DT feature (VolumeRadTM) on the GE DefiniumTM 8000 flat panel system installed in the Winnipeg Children's Hospital. Facial bones, cervical spine, thoracic spine, and knee of children aged 5, 10, and 15 years were represented by acrylic phantoms for DT dose measurements. Effective dose was estimated for DT and for corresponding digital radiography (DR) and computed tomography (CT) patient image sets. Anthropomorphic phantoms of selected body parts were imaged by DR, DT, and CT. Pediatric radiologists rated visualization of selected anatomic features in these images. Dose and image quality comparisons between DR, DT, and CT determined the usefulness of tomosynthesis for pediatric imaging. CT effective dose was highest; total DR effective dose was not always lowest - depending how many projections were in the DR image set. For the cervical spine, DT dose was close to and occasionally lower than DR dose. Expert radiologists rated visibility of the central facial complex in a skull phantom as better than DR and comparable to CT. Digital tomosynthesis has a significantly lower dose than CT. This study has demonstrated DT shows promise to replace CT for some facial bones and spinal diagnoses. Other clinical applications will be evaluated in the future.

A review of Education and Social Media using functionalist and conflict theories of educational purposes

NASA Astrophysics Data System (ADS)

Cian, Heidi; Amann, Holly

2017-11-01

Education and Social Media: Toward a Digital Future (2016), edited by Christine Greenhow, Julia Sonnevend, and Colin Agur, is a compilation of essays by leading contributors to the digital and social media movement in education. The chapters within this volume provide a granular look at the current landscape of how digital media is utilized across educational levels, fields of study, and geographic areas. The book is divided into three sections discussing the emerging use of social media in education, challenges in its implementation, and potential directions as tech-based education continues to evolve. In this review, we situate the ideas presented in Education and Social Media in the functionalist and conflict theories of educational perspective to further illuminate the potential of digital learning in supporting increased access to education for marginalized student populations. We discuss how these competing views are both given voice in Education and Social Media, prompting the reader to critically reflect on advantages and dangers presented by increased use of technological platforms in educational settings. Topics discussed include online universities, peer-developed curriculum, and differential use of technology based on school socioeconomic demographics. We also suggest areas that have emerged in need of further discussion since the book's publication.

Digital Object Identifiers (DOI's) usage and adoption in U.S Geological Survey (USGS)

NASA Astrophysics Data System (ADS)

Frame, M. T.; Palanisamy, G.

2013-12-01

Addressing grand environmental science challenges requires unprecedented access to easily understood data that cross the breadth of temporal, spatial, and thematic scales. From a scientist's perspective, the big challenges lie in discovering the relevant data, dealing with extreme data heterogeneity, large data volumes, and converting data to information and knowledge. Historical linkages between derived products, i.e. Publications, and associated datasets has not existed in the earth science community. The USGS Core Science Analytics and Synthesis, in collaboration with DOE's Oak Ridge National Laboratory (ORNL) Mercury Consortium (funded by NASA, USGS and DOE), established a Digital Object Identifier (DOI) service for USGS data, metadata, and other media. This service is offered in partnership through the University of California Digital Library EZID service. USGS scientists, data managers, and other professionals can generate globally unique, persistent and resolvable identifiers for any kind of digital objects. Additional efforts to assign DOIs to historical data and publications have also been underway. These DOI identifiers are being used to cite data in journal articles, web-accessible datasets, and other media for distribution, integration, and in support of improved data management practices. The session will discuss the current DOI efforts within USGS, including a discussion on adoption, challenges, and future efforts necessary to improve access, reuse, sharing, and discoverability of USGS data and information.

Creating an anthropomorphic digital MR phantom—an extensible tool for comparing and evaluating quantitative imaging algorithms

NASA Astrophysics Data System (ADS)

Bosca, Ryan J.; Jackson, Edward F.

2016-01-01

Assessing and mitigating the various sources of bias and variance associated with image quantification algorithms is essential to the use of such algorithms in clinical research and practice. Assessment is usually accomplished with grid-based digital reference objects (DRO) or, more recently, digital anthropomorphic phantoms based on normal human anatomy. Publicly available digital anthropomorphic phantoms can provide a basis for generating realistic model-based DROs that incorporate the heterogeneity commonly found in pathology. Using a publicly available vascular input function (VIF) and digital anthropomorphic phantom of a normal human brain, a methodology was developed to generate a DRO based on the general kinetic model (GKM) that represented realistic and heterogeneously enhancing pathology. GKM parameters were estimated from a deidentified clinical dynamic contrast-enhanced (DCE) MRI exam. This clinical imaging volume was co-registered with a discrete tissue model, and model parameters estimated from clinical images were used to synthesize a DCE-MRI exam that consisted of normal brain tissues and a heterogeneously enhancing brain tumor. An example application of spatial smoothing was used to illustrate potential applications in assessing quantitative imaging algorithms. A voxel-wise Bland-Altman analysis demonstrated negligible differences between the parameters estimated with and without spatial smoothing (using a small radius Gaussian kernel). In this work, we reported an extensible methodology for generating model-based anthropomorphic DROs containing normal and pathological tissue that can be used to assess quantitative imaging algorithms.

Digital quantification of DNA via isothermal amplification on a self-driven microfluidic chip featuring hydrophilic film-coated polydimethylsiloxane.

PubMed

Ma, Yu-Dong; Chang, Wen-Hsin; Luo, Kang; Wang, Chih-Hung; Liu, Shih-Yuan; Yen, Wen-Hsiang; Lee, Gwo-Bin

2018-01-15

Loop-mediated isothermal amplification (LAMP) is a DNA amplification approach characterized by high sensitivity and specificity. In "digital LAMP", small quantities of both template DNA and reagents are encapsulated within a droplet or microwell, allowing for analysis of precious nucleic acid samples in shorter amounts of time relative to traditional DNA amplification protocols (e.g., PCR) with an improved limit of detection. In this study, an integrated, self-driven microfluidic chip was designed to carry out digital LAMP. The entire quantification process could be automatically performed on this chip via capillary forces enabled through microwells comprised of polydimethylsiloxane (PDMS) surfaces coated with a hydrophilic film; no external pumps were required. Moreover, digitized droplets could be separated from each other by normally-closed microvalves. The contact angle of the hydrophilic film-coated PDMS surface was only 14.3°. This is the first time that a rapid (30min) and simple method has been used to create hydrophilic PDMS surfaces that allow for digital LAMP to be performed in a self-driven microfluidic device. As a proof of concept, amplification of a gene specific to a vancomycin-resistant Enterococcus strain was performed on the developed microfluidic chip within 30min, and the limit of detection was only 11 copies with a volume of 30μL. This device may therefore become a promising tool for clinical diagnosis and point-of-care applications. Copyright © 2017 Elsevier B.V. All rights reserved.